Proton magnetic resonance spectroscopy shows lower intramyocellular lipid accumulation in middle-aged subjects predisposed to familial longevity.

Science.gov (United States)

Wijsman, C A; van Opstal, A M; Kan, H E; Maier, A B; Westendorp, R G J; Slagboom, P E; Webb, A G; Mooijaart, S P; van Heemst, D

2012-02-01

Families predisposed to longevity show enhanced glucose tolerance and skeletal muscle insulin sensitivity compared with controls, independent of body composition and physical activity. Intramyocellular lipid (IMCL) accumulation in skeletal muscle has been associated with insulin resistance. Here, we assessed whether subjects enriched for familial longevity have lower IMCL levels. We determined IMCL levels in 48 subjects from the Leiden Longevity Study, comprising 24 offspring of nonagenarian siblings and 24 partners thereof as control subjects. IMCL levels were assessed noninvasively using short echo time proton magnetic resonance spectroscopy ((1)H-MRS) of the tibialis anterior muscle with a 7 Tesla human MR scanner. IMCL levels were calculated relative to the total creatine (tCr) CH3 signal. Physical activity was assessed using the International Physical Activity Questionnaire (IPAQ). After correction for age, sex, BMI, and physical activity, offspring of long-lived nonagenarian siblings tended to show lower IMCL levels compared with controls (IMCL/tCr: 3.1 ± 0.5 vs. 4.5 ± 0.5, respectively, P = 0.051). In a pairwise comparison, this difference reached statistical significance (P = 0.038). We conclude that offspring of nonagenarian siblings predisposed to longevity show lower IMCL levels compared with environmentally matched control subjects. Future research should focus on assessing what mechanisms may explain the lower IMCL levels in familial longevity.

Glycemic markers and relation with arterial stiffness in Caucasian subjects of the MARK study.

Directory of Open Access Journals (Sweden)

Leticia Gomez-Sanchez

Full Text Available Effect of prediabetes and normal glucose on arterial stiffness remains controversial. The primary aim of this study was to investigate the relationship of fasting plasma glucose (FPG, postprandial glucose (PG and glycosylated haemoglobin (HbA1c with brachial-ankle pulse wave velocity (baPWV and cardio-ankle vascular index (CAVI in Caucasian adults. The secondary aim was to analyse this relationship by glycaemic status.Cross-sectional study. Setting: Primary care. Participants: 2,233 subjects, 35-74 years. Measures: FPG (mg/dL and HbA1c (% of all subjects were measured using standard automated enzymatic methods. PG (mg/dL was self-measured at home two hours after meals (breakfast, lunch and dinner for one day using an Accu-chek ® glucometer. CAVI was measured using a VaSera VS-1500® device (Fukuda Denshi, and baPWV was calculated using a validated equation.CAVI and baPWV values were significantly higher in subjects with diabetes mellitus than in glucose normal and prediabetes groups (p<0.001. FPG, PG and HbA1c were positively associated with CAVI and baPWV. The β regression coefficient for: HbA1c was 0.112 (CI 95% 0.068 to 0.155 with CAVI, 0.266 (CI 95% 0.172 to 0.359 with baPWV; for PG was 0.006 (CI 95% 0.004 to 0.009 and for FPG was 0.005 (CI 95% 0.002 to 0.008 with baPWV; and for PG was 0.002 (CI 95% 0.001 to 0.003 and 0.003 (CI 95% 0.002 to 0.004 with CAVI (p<0.01 in all cases. When analysing by hyperglycaemic status, FPG, PG and HbA1c were positively associated with CAVI and baPWV in subjects with type 2 diabetes mellitus.FPG, PG and HbA1c show a positive association with CAVI and baPWV, in Caucasian adults with intermediate cardiovascular risk factors. When analysing by hyperglycaemic status, the association is only maintained in subjects with type 2 diabetes mellitus.Clinical Trials.gov Identifier: NCT01428934. Registered 2 September 2011. Retrospectively registered. Last updated September 8, 2016.

75 FR 22727 - Defense Federal Acquisition Regulation Supplement; Government-Assigned Serial Number Marking...

Science.gov (United States)

2010-04-30

... 252.211-7003, Item Identification and Valuation, and that require the contractor to mark major end... existing DoD property management, logistics, and maintenance systems. This regulatory action was subject to... operational necessity. The latest version of MIL-STD-130, Marking of U.S. Military Property, shall be used for...

Enamel-based mark performance for marking Chinese mystery snail Bellamya chinensis

Science.gov (United States)

Wong, Alec; Allen, Craig R.; Hart, Noelle M.; Haak, Danielle M.; Pope, Kevin L.; Smeenk, Nicholas A.; Stephen, Bruce J.; Uden, Daniel R.

2013-01-01

The exoskeleton of gastropods provides a convenient surface for carrying marks, and i the interest of improving future marking methods our laboratory assessed the performance of an enamel paint. The endurance of the paint was also compared to other marking methods assessed in the past. We marked the shells of 30 adult Chinese mystery snails Bellamya chinensis and held them in an aquarium for 181 days. We observed no complete degradation of any enamel-paint mark during the 181 days. The enamel-paint mark was superior to a nai;-polish mark, which lasted a median of 100 days. Enamel-paint marks also have a lower rate of loss (0.00 month-1 181 days) than plastic bee tags (0.01 month-1, 57 days), gouache paint (0.07 month-1, 18.5 days), or car body paint from studies found in scientific literature. Legibility of enamel-paint marks had a median lifetime of 102 days. The use of enamel paint on the shells of gastropods is a viable option for studies lasting up to 6 months. Furthermore, visits to capture-mark-recapture site 1 year after application of enamel-paint marks on B. chinesnis shells produced several individuals on which the enamel paint was still visible, although further testing is required to clarify durability over longer periods.

Statistical methods for the forensic analysis of striated tool marks

Energy Technology Data Exchange (ETDEWEB)

Hoeksema, Amy Beth [Iowa State Univ., Ames, IA (United States)

2013-01-01

In forensics, fingerprints can be used to uniquely identify suspects in a crime. Similarly, a tool mark left at a crime scene can be used to identify the tool that was used. However, the current practice of identifying matching tool marks involves visual inspection of marks by forensic experts which can be a very subjective process. As a result, declared matches are often successfully challenged in court, so law enforcement agencies are particularly interested in encouraging research in more objective approaches. Our analysis is based on comparisons of profilometry data, essentially depth contours of a tool mark surface taken along a linear path. In current practice, for stronger support of a match or non-match, multiple marks are made in the lab under the same conditions by the suspect tool. We propose the use of a likelihood ratio test to analyze the difference between a sample of comparisons of lab tool marks to a field tool mark, against a sample of comparisons of two lab tool marks. Chumbley et al. (2010) point out that the angle of incidence between the tool and the marked surface can have a substantial impact on the tool mark and on the effectiveness of both manual and algorithmic matching procedures. To better address this problem, we describe how the analysis can be enhanced to model the effect of tool angle and allow for angle estimation for a tool mark left at a crime scene. With sufficient development, such methods may lead to more defensible forensic analyses.

Bench-marking effects in the blaming of professionals for incidents of aggression and assault.

Science.gov (United States)

Carifio, J; Lanza, M

1994-01-01

This study compared all possible orders of responding to three vignettes describing incidents between a male patient and a female nurse in which the nurse is mildly assaulted, severely assaulted, or verbally abused by the patient (the control condition). Subjects were 32 female senior-year nursing students and 28 practicing nurses. It was found that response levels to a given vignette could predict a respondent's response to the other vignettes. Also, a significant "bench-marking" effect was found: if a subject responded to the mild assault vignette first, the subject's overall response pattern best fit the general nonlinear assignment-of-blame pattern observed, but if the subject responded to the severe assault or control vignette first, this vignette set a bench mark for responding from which the subject's subsequent responses did not deviate greatly, which slightly distorted the subject's V-shaped nonlinear response pattern.

Older people experiencing homelessness show marked impairment on tests of frontal lobe function.

Science.gov (United States)

Rogoz, Astrid; Burke, David

2016-03-01

Reported rates of mild and moderate cognitive impairment in older people experiencing homelessness range from 5-80%. The objective of this study was to determine the prevalence and characteristics of cognitive impairment in older people experiencing homelessness in the inner city of Sydney, Australia. Men and women experiencing homelessness aged 45 years and over in the inner city were screened for cognitive impairment. Participants who scored 26 or below on the mini-mental state examination and/or were impaired on any one of the clock-drawing test, the verbal fluency test and the trail-making test, part B were then assessed with a semi-structured interview, including the 21-item Depression Anxiety Stress Scale and the 12-item General Health Questionnaire. Screening of 144 men and 27 women aged between 45 years and 93 years identified cognitive impairment in 78%. Subsequently, high rates of mental and physical illness were identified, and 75% of subjects who were cognitively impaired performed poorly on frontal lobe tests. The trail-making test, part B was the most sensitive measure of frontal function. This study demonstrated that a large majority of older people experiencing homelessness, in the inner city of a high-income country, showed impairment on tests of frontal lobe function, a finding that could have significant implications for any medical or psychosocial intervention. Copyright © 2015 John Wiley & Sons, Ltd.

Coupled Imaging with [18F]FBB and [18F]FDG in AD Subjects Show a Selective Association Between Amyloid Burden and Cortical Dysfunction in the Brain.

Science.gov (United States)

Chiaravalloti, Agostino; Castellano, Anna Elisa; Ricci, Maria; Barbagallo, Gaetano; Sannino, Pasqualina; Ursini, Francesco; Karalis, Georgios; Schillaci, Orazio

2018-02-05

The present study was aimed to investigate the relationships between dysfunction of cortical glucose metabolism as detectable by means of 2-deoxy-2-[ 18 F]fluoro -D-glucose ([ 18 F]FDG) positron emission tomography/x-ray computed tomography (PET/CT) and amyloid burden as detectable by means of 4-{(E)-2-[4-(2-{2-[2-[ 18 F]fluoroethoxy]ethoxy}ethoxy)phenyl]vinyl}-N-methylaniline (florbetaben; [ 18 F]FBB) in a group of patients affected by Alzheimer's disease (AD). We examined 38 patients newly diagnosed with AD according to the NINCDS-ADRDA criteria. All the subjects underwent a PET/CT scan using both [ 18 F]FDG and [ 18 F]FBB with an average interval of 1 month. We used statistical parametric mapping (SPM8) implemented in Matlab R2012b and WFU pickatlas for the definition of a region of interest (ROI) mask including the whole cortex. These data were then normalized on the counts of the cerebellum and then used for a regression analysis on [ 18 F]FDG scans in SPM. Furthermore, 58 control subjects were used as control group for [ 18 F]FDG PET/CT scans. SPM analysis in AD patients showed a significant negative correlation between [ 18 F] FBB and [ 18 F] FDG uptake in temporal and parietal lobes bilaterally. Of note, these areas in AD patients displayed a marked glucose hypometabolism compared to control group. Combined imaging with [ 18 F]FBB and [ 18 FFDG shows that amyloid burden in the brain is related to cortical dysfunction of temporal and parietal lobes in AD.

Evaluation of portable retroreflectometer for use on pavement marking materials.

Science.gov (United States)

1981-01-01

The subjective rating of the night visibility of pavement marking materials is difficult as it can be influenced by many variables. In an attempt to provide an improved method of determining the night visibility of these materials, a portable retrore...

Giant pandas failed to show mirror self-recognition.

Science.gov (United States)

Ma, Xiaozan; Jin, Yuan; Luo, Bo; Zhang, Guiquan; Wei, Rongping; Liu, Dingzhen

2015-05-01

Mirror self-recognition (MSR), i.e., the ability to recognize oneself in a mirror, is considered a potential index of self-recognition and the foundation of individual development. A wealth of literature on MSR is available for social animals, such as chimpanzees, Asian elephants and dolphins, yet little is known about MSR in solitary mammalian species. We aimed to evaluate whether the giant panda can recognize itself in the mirror, and whether this capacity varies with age. Thirty-four captive giant pandas (F:M = 18:16; juveniles, sub-adults and adults) were subjected to four mirror tests: covered mirror tests, open mirror tests, water mark control tests, and mark tests. The results showed that, though adult, sub-adult and juvenile pandas exposed to mirrors spent similar amounts of time in social mirror-directed behaviors (χ(2) = 0.719, P = 0.698), none of them used the mirror to touch the mark on their head, a self-directed behavior suggesting MSR. Individuals of all age groups initially displayed attacking, threatening, foot scraping and backwards walking behaviors when exposed to their self-images in the mirror. Our data indicate that, regardless of age, the giant pandas did not recognize their self-image in the mirror, but instead considered the image to be a conspecific. Our results add to the available information on mirror self-recognition in large mammals, provide new information on a solitary species, and will be useful for enclosure design and captive animal management.

COMPUTER HARDWARE MARKING

CERN Multimedia

Groupe de protection des biens

2000-01-01

As part of the campaign to protect CERN property and for insurance reasons, all computer hardware belonging to the Organization must be marked with the words 'PROPRIETE CERN'.IT Division has recently introduced a new marking system that is both economical and easy to use. From now on all desktop hardware (PCs, Macintoshes, printers) issued by IT Division with a value equal to or exceeding 500 CHF will be marked using this new system.For equipment that is already installed but not yet marked, including UNIX workstations and X terminals, IT Division's Desktop Support Service offers the following services free of charge:Equipment-marking wherever the Service is called out to perform other work (please submit all work requests to the IT Helpdesk on 78888 or helpdesk@cern.ch; for unavoidable operational reasons, the Desktop Support Service will only respond to marking requests when these coincide with requests for other work such as repairs, system upgrades, etc.);Training of personnel designated by Division Leade...

Factors affecting scent-marking behaviour in Eurasion beaver (Castor fiber)

NARCIS (Netherlands)

Rosell, F.; Nolet, B.A.

1997-01-01

We tested the hypothesis that a main function of territory marking in Eurasian beaver (Castor fiber) is defense of the territory. The results showed that: (1) beaver colonies with close neighbors scent-mark more often than isolated ones; (2) the number of scent markings increased significantly with

Factors influencing survival and mark retention in postmetamorphic boreal chorus frogs

Science.gov (United States)

Swanson, Jennifer E; Bailey, Larissa L.; Muths, Erin L.; Funk, W. Chris

2013-01-01

The ability to track individual animals is crucial in many field studies and often requires applying marks to captured individuals. Toe clipping has historically been a standard marking method for wild amphibian populations, but more recent marking methods include visual implant elastomer and photo identification. Unfortunately, few studies have investigated the influence and effectiveness of marking methods for recently metamorphosed individuals and as a result little is known about this life-history phase for most amphibians. Our focus was to explore survival probabilities, mark retention, and mark migration in postmetamorphic Boreal Chorus Frogs (Psuedacris maculata) in a laboratory setting. One hundred forty-seven individuals were assigned randomly to two treatment groups or a control group. Frogs in the first treatment group were marked with visual implant elastomer, while frogs in the second treatment group were toe clipped. Growth and mortality were recorded for one year and resulting data were analyzed using known-fate models in Program MARK. Model selection results suggested that survival probabilities of frogs varied with time and showed some variation among marking treatments. We found that frogs with multiple toes clipped on the same foot had lower survival probabilities than individuals in other treatments, but individuals can be marked by clipping a single toe on two different feet without any mark loss or negative survival effects. Individuals treated with visual implant elastomer had a mark migration rate of 4% and mark loss rate of 6%, and also showed very little negative survival impacts relative to control individuals.

The use of computerized tomography in patients showing tardive dyskinesia

International Nuclear Information System (INIS)

Themelis, I.

1983-01-01

29 patients showing moderate to markedly pronounced tardive dyskinesia (TD) and a further 29 control patients (C) under a similar long-term medication with neuroleptics that had been so chosen as to match the age and sex distributions of the former group were subjected to computered tomography, neurological examination and psychological testing. The results did not point to any correlations between the structural changes and duration of treatment and the clinical signs or symptoms of extrapyramidal disorder. This was taken as further evidence in support of the theory that the initial damage in tardive dyskinesia mainly is at the level of the basal ganglia. (orig./MG) [de

Prosodic Focus Marking in Bai.

NARCIS (Netherlands)

Liu, Zenghui; Chen, A.; Van de Velde, Hans

2014-01-01

This study investigates prosodic marking of focus in Bai, a Sino-Tibetan language spoken in the Southwest of China, by adopting a semi-spontaneous experimental approach. Our data show that Bai speakers increase the duration of the focused constituent and reduce the duration of the post-focus

Mark Tompkins Canaccord

OpenAIRE

Mark Tompkins Canaccord

2018-01-01

Mark Tompkins Canaccord is a senior technologist for ecosystem and water resources management in SEC SAID Oakland, California office. In his career which lasts over fifteen years Mark has worked on project involving lake restorations, clean water engineering, ecological engineering and management, hydrology, hydraulics, sediment transport and other projects for environmental planning all over the country. Mark Tompkins Canaccord tries to blend his skills of planning and engineering with s...

Reconfiguring trade mark law

DEFF Research Database (Denmark)

Elsmore, Matthew James

2013-01-01

-border setting, with a particular focus on small business and consumers. The article's overall message is to call for a rethink of received wisdom suggesting that trade marks are effective trade-enabling devices. The case is made for reassessing how we think about European trade mark law.......First, this article argues that trade mark law should be approached in a supplementary way, called reconfiguration. Second, the article investigates such a reconfiguration of trade mark law by exploring the interplay of trade marks and service transactions in the Single Market, in the cross...

Identifying persistent and characteristic features in firearm tool marks on cartridge cases

Science.gov (United States)

Ott, Daniel; Soons, Johannes; Thompson, Robert; Song, John

2017-12-01

Recent concerns about subjectivity in forensic firearm identification have motivated the development of algorithms to compare firearm tool marks that are imparted on ammunition and to generate quantitative measures of similarity. In this paper, we describe an algorithm that identifies impressed tool marks on a cartridge case that are both consistent between firings and contribute strongly to a surface similarity metric. The result is a representation of the tool mark topography that emphasizes both significant and persistent features across firings. This characteristic surface map is useful for understanding the variability and persistence of the tool marks created by a firearm and can provide improved discrimination between the comparison scores of samples fired from the same firearm and the scores of samples fired from different firearms. The algorithm also provides a convenient method for visualizing areas of similarity that may be useful in providing quantitative support for visual comparisons by trained examiners.

BWR Mark I pressure suppression study: bench mark experiments

International Nuclear Information System (INIS)

Lai, W.; McCauley, E.W.

1977-01-01

Computer simulations representative of the wetwell of Mark I BWR's have predicted pressures and related phenomena. However, calculational predictions for purposes of engineering decision will be possible only if the code can be verified, i.e., shown to compute in accord with measured values. Described in the report is a set of single downcomer spherical flask bench mark experiments designed to produce quantitative data to validate various air-water dynamic computations; the experiments were performed since relevant bench mark data were not available from outside sources. Secondary purposes of the study were to provide a test bed for the instrumentation and post-experiment data processing techniques to be used in the Laboratory's reactor safety research program and to provide additional masurements for the air-water scaling study

Elemental marking of arthropod pests in agricultural systems: single and multigenerational marking

Science.gov (United States)

Jane Leslie Hayes

1991-01-01

Use of elemental markers to study movement of arthropod pests of field crops is reviewed. Trace elements, rubidium (Rb) and cesium (Cs), have provided a nondisruptive method of marking natural adult populations via developmental stage consumption of treated host plants. Multigenerational marking occurs with the transfer of elemental markers from marked adults to...

Detection and recognition of road markings in panoramic images

Science.gov (United States)

Li, Cheng; Creusen, Ivo; Hazelhoff, Lykele; de With, Peter H. N.

2015-03-01

Detection of road lane markings is attractive for practical applications such as advanced driver assistance systems and road maintenance. This paper proposes a system to detect and recognize road lane markings in panoramic images. The system can be divided into four stages. First, an inverse perspective mapping is applied to the original panoramic image to generate a top-view road view, in which the potential road markings are segmented based on their intensity difference compared to the surrounding pixels. Second, a feature vector of each potential road marking segment is extracted by calculating the Euclidean distance between the center and the boundary at regular angular steps. Third, the shape of each segment is classified using a Support Vector Machine (SVM). Finally, by modeling the lane markings, previous falsely detected segments can be rejected based on their orientation and position relative to the lane markings. Our experiments show that the system is promising and is capable of recognizing 93%, 95% and 91% of striped line segments, blocks and arrows respectively, as well as 94% of the lane markings.

Differential Signature of the Centrosomal MARK4 Isoforms in Glioma

Directory of Open Access Journals (Sweden)

Ivana Magnani

2011-01-01

Full Text Available Background: MAP/microtubule affinity-regulating kinase 4 (MARK4 is a serine-threonine kinase expressed in two spliced isoforms, MARK4L and MARK4S, of which MARK4L is a candidate for a role in neoplastic transformation. Methods: We performed mutation analysis to identify sequence alterations possibly affecting MARK4 expression. We then investigated the MARK4L and MARK4S expression profile in 21 glioma cell lines and 36 tissues of different malignancy grades, glioblastoma-derived cancer stem cells (GBM CSCs and mouse neural stem cells (NSCs by real-time PCR, immunoblotting and immunohistochemistry. We also analyzed the sub-cellular localisation of MARK4 isoforms in glioma and normal cell lines by immunofluorescence. Results: Mutation analysis rules out sequence variations as the cause of the altered MARK4 expression in glioma. Expression profiling confirms that MARK4L is the predominant isoform, whereas MARK4S levels are significantly decreased in comparison and show an inverse correlation with tumour grade. A high MARK4L/MARK4S ratio also characterizes undifferentiated cells, such as GBM CSCs and NSCs. Accordingly, only MARK4L is expressed in brain neurogenic regions. Moreover, while both MARK4 isoforms are localised to the centrosome and midbody in glioma and normal cells, the L isoform exhibits an additional nucleolar localisation in tumour cells. Conclusions: The observed switch towards MARK4L suggests that the balance between the MARK4 isoforms is carefully guarded during neural differentiation but may be subverted in gliomagenesis. Moreover, the MARK4L nucleolar localisation in tumour cells features this MARK4 isoform as a nucleolus-associated tumour marker.

Mark retention of calcein in Cisco and Bloater

Science.gov (United States)

Chalupnicki, Marc A.; Mackey, Gregg; Nash, Kendra; Chiavelli, Richard; Johnson, James H.; Kehler, Thomas; Ringler, Neil H.

2016-01-01

Since 2012, a multi-agency initiative to restore these native forage species has been under way. Evaluating the restoration success of Cisco Coregonus artedi and Bloater C. hoyi in Lake Ontario waters requires methods to identify stocked fish. However, juvenile Cisco and Bloater are fragile; thus, mass marking techniques that reduce the handling of individual fish are required and have not previously been evaluated. In 2014–2015 we evaluated the usefulness of calcein (SE-MARK) as a marker on bony structures, including the otolith. Juvenile Bloater and Cisco (14, 100, 128 d old) were immersed in a calcein bath at 5,000 mg/L of water for 4 min to apply the chemical marker. Observations of the marking retention were evaluated 8 d following the treatment. All fish immersed in calcein had strong brilliant marks (rating scale 3) on all bony structures including scales, fin rays, jaw bones, and vertebrate. The otolith was the only hard structure that did not show a brilliant marking due to the opaque nature of the structure. Our results suggest that calcein produces a strong discernable mark on hard bony structures of Cisco and Bloater; however, long-term retention needs further study.

Electrofishing mark-recapture and depletion methodologies evoke behavioral and physiological changes in cutthroat trout

Science.gov (United States)

Mesa, M. G.; Schreck, C.B.

1989-01-01

We examined the behavioral and physiological responses of wild and hatchery-reared cutthroat trout Oncorhynchus clarki subjected to a single electroshock, electroshock plus marking, and multiple electroshocks in natural and artificial streams. In a natural stream, cutthroat trout released after capture by electrofishing and marking showed distinct behavioral changes: fish immediately sought cover, remained relatively inactive, did not feed, and were easily approached by a diver. An average of 3–4 h was required for 50% of the fish to return to a seemingly normal mode of behavior, although responses varied widely among collection sites. Using the depletion method, we observed little change in normal behavior offish remaining in the stream section (i.e., uncaptured fish) after successive passes with electrofishing gear. In an artificial stream, hatchery-reared and wild cutthroat trout immediately decreased their rates of feeding and aggression after they were electroshocked and marked. Hatchery fish generally recovered in 2–3 h; wild fish required at least 24 h to recover. Analysis of feeding and aggression data by hierarchical rank revealed no distinct recovery trends among hatchery fish of different ranks; among wild cutthroat trout, however, socially dominant fish seemed to recover faster than intermediate and subordinate fish. Physiological indicators of stress (plasma cortisol and blood lactic acid) increased significantly in cutthroat trout subjected to electroshock plus marking or single or multiple electroshocks. As judged by the magnitude of the greatest change in cortisol and lactate, multiple electroshocks elicited the most severe stress response; however, plasma concentrations of both substances had returned to unstressed control levels by 6 h after treatment. It was evident that electrofishing and the procedures involved with estimating fish population size elicited a general stress response that was manifested not only physiologically but also

Infrared technique for decoding of invisible laser markings

Science.gov (United States)

Haferkamp, Heinz; Jaeschke, Peter; Stein, Johannes; Goede, Martin

2002-03-01

Counterfeiting and product piracy continues to be an important issue not only for the Western industry, but also for the society in general. Due to the drastic increase in product imitation and the request for plagiarism protection as well as for reducing thefts there is a high interest in new protection methods providing new security features. The method presented here consists of security markings which are included below paint layers. These markings are invisible for the human eye due to the non-transparency of the upper layers in the visible spectral range. However, the markings can be detected by an infrared technique taking advantage on the partial transparency of the upper paint layers in the IR-region. Metal sheets are marked using laser radiation. The beam of a Nd:YAG-laser provides a modification of the surface structure, resulting in dark markings due to the annealing effect. After coating of the laser-marked material, the markings are invisible for the bare eye. In order to read out the invisible information below the coating, an infrared reflection technique is used. The samples are illuminated with halogen lamps or infrared radiators. Many coating materials (i. e. paints) show a certain transparency in the mid-infrared region, especially between 3 - 5 micrometers . The reflected radiation is detected using an IR-camera with a sensitivity range from 3.4 - 5 micrometers . Due to the different reflection properties between the markings and their surrounding, the information can be detected.

Manikin-Based Size-Resolved Penetrations of CE-marked Filtering Facepiece Respirators.

Czech Academy of Sciences Publication Activity Database

Serfozo, N.; Ondráček, Jakub; Otáhal, P.; Lazaridis, M.; Ždímal, Vladimír

2017-01-01

Roč. 14, č. 12 (2017), s. 965-974 ISSN 1545-9624 EU Projects: European Commission(XE) 315760 - HEXACOMM Institutional support: RVO:67985858 Keywords : size-resolved penetration * manikin-based study * CE-marked respirator Subject RIV: CF - Physical ; Theoretical Chemistry OBOR OECD: Physical chemistry Impact factor: 1.200, year: 2016

The value of bone scintigram in elderly subjects

International Nuclear Information System (INIS)

Tanno, Munehiko; Yamada, Hideo; Hayashida, Koichi; Endoh, Kazuo; Nagashima, Junichi; Yamagata, Atsushi; Nishino, Hideo; Chiba, Kazuo

1986-01-01

To evaluate increased bone uptake of radionuclides at lumbar vertebra in elderly subjects, comparative study of bone scintigram with CT findings and autopsy finding of bone were performed. Incidence of abnormal increased bone uptake were 59 % in neoplastic disease group, while 50 % in benign disease group, respectively. Bone uptake of radionuclides to thoracic and lumbar vertebrae revealed marked high incidence even in both group. 13 out of 25 cases which revealed bone uptake at lumbar vertebrae in malignant disease group showed metastatic bone lesions and the rest of these cases did not show no apparent macroscopic metastatic bone lesions. In comparative study with CT findings of 18 cases most cases revealed osteosclerotic and osteoperotic changes of bone and fracture on CT imaging at the sites where bone uptake of radionuclides were observed. Thus, these evidence support that ageing process of bone must be considered as important factors to evaluate bone scintigram imaging in elderly subjects. (author)

Microbial analysis of bite marks by sequence comparison of streptococcal DNA.

Directory of Open Access Journals (Sweden)

Darnell M Kennedy

Full Text Available Bite mark injuries often feature in violent crimes. Conventional morphometric methods for the forensic analysis of bite marks involve elements of subjective interpretation that threaten the credibility of this field. Human DNA recovered from bite marks has the highest evidentiary value, however recovery can be compromised by salivary components. This study assessed the feasibility of matching bacterial DNA sequences amplified from experimental bite marks to those obtained from the teeth responsible, with the aim of evaluating the capability of three genomic regions of streptococcal DNA to discriminate between participant samples. Bite mark and teeth swabs were collected from 16 participants. Bacterial DNA was extracted to provide the template for PCR primers specific for streptococcal 16S ribosomal RNA (16S rRNA gene, 16S-23S intergenic spacer (ITS and RNA polymerase beta subunit (rpoB. High throughput sequencing (GS FLX 454, followed by stringent quality filtering, generated reads from bite marks for comparison to those generated from teeth samples. For all three regions, the greatest overlaps of identical reads were between bite mark samples and the corresponding teeth samples. The average proportions of reads identical between bite mark and corresponding teeth samples were 0.31, 0.41 and 0.31, and for non-corresponding samples were 0.11, 0.20 and 0.016, for 16S rRNA, ITS and rpoB, respectively. The probabilities of correctly distinguishing matching and non-matching teeth samples were 0.92 for ITS, 0.99 for 16S rRNA and 1.0 for rpoB. These findings strongly support the tenet that bacterial DNA amplified from bite marks and teeth can provide corroborating information in the identification of assailants.

Subjective versus objective assessment of breast reconstruction.

Science.gov (United States)

Henseler, Helga; Smith, Joanna; Bowman, Adrian; Khambay, Balvinder S; Ju, Xiangyang; Ayoub, Ashraf; Ray, Arup K

2013-05-01

To date breast assessment has been conducted mainly subjectively. However lately validated objective three-dimensional (3D) imaging was developed. The study aimed to assess breast reconstruction subjectively and objectively and conduct a comparison. In forty-four patients after immediate unilateral breast reconstruction with solely the extended latissimus dorsi flap the breast was captured by validated 3D imaging method and standardized 2D photography. Breast symmetry was subjectively evaluated by six experts who applied the Harris score giving a mark of 1-4 for a poor to excellent result. An error study was conducted by examination of the intra and inter-observer agreement and agreement on controls. By Procrustes analysis an objective asymmetry score was obtained and compared to the subjective assessment. The subjective assessment showed that the inter-observer agreement was good or substantial (p-value: value: fair (p-values: 0.159, 0.134, 0.099) to substantial (p-value: 0.005) intra-observer agreement. The objective assessment revealed that the reconstructed breast showed a significantly smaller volume compared to the opposite side and that the average asymmetry score was 0.052, ranging from 0.019 to 0.136. When comparing the subjective and objective method the relationship between the two scores was highly significant. Subjective breast assessment lacked accuracy and reproducibility. This was the first error study of subjective breast assessment versus an objective validated 3D imaging method based on true 3D parameters. The substantial agreement between established subjective breast assessment and new validated objective method supported the value of the later and we expect its future role to expand. Copyright © 2013 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

Bite marks in mink—Induced experimentally and as reflection of aggressive encounters between mink

DEFF Research Database (Denmark)

Hansen, Steffen W; Møller, Steen Henrik; Damgaard, Birthe Marie

2014-01-01

of the brown colour type (N = 140) and the white colour type (N = 60). Twentybrown and 20 white mink (housed in pairs since weaning) were housed individually at theage of 16 weeks. Every second week (at the age of 20, 22, 24, 25 and 28 weeks), four brownand four white mink were subjected to pressure......: (1) experimentally applied pressure on the skin can be recog-nized as bite marks in brown mink at pelting, (2) bite marks are easier to detect on brownmink than on white coloured mink (P ...tFor many years, bite marks have been used as an indicator for aggression in mink productionsystems. However, the validity of bite marks as indicator of aggression has recently beenquestioned. We therefore tested the following hypotheses: (1) experimentally applied pressure to, or penetration of...

Lujan Mark-4

Energy Technology Data Exchange (ETDEWEB)

Mocko, Michael Jeffrey [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Zavorka, Lukas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Koehler, Paul E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2017-11-13

This is a review of Mark-IV target neutronics design. It involved the major redesign of the upper tier, offering harder neutron spectra for upper-tier FPs; a redesign of the high-resolution (HR) moderator; and a preservation of the rest of Mark-III features.

Minimal Marking: A Success Story

Science.gov (United States)

McNeilly, Anne

2014-01-01

The minimal-marking project conducted in Ryerson's School of Journalism throughout 2012 and early 2013 resulted in significantly higher grammar scores in two first-year classes of minimally marked university students when compared to two traditionally marked classes. The "minimal-marking" concept (Haswell, 1983), which requires…

Mark Stock | NREL

Science.gov (United States)

Stock Mark Stock Scientific Visualization Specialist Mark.Stock@nrel.gov | 303-275-4174 Dr. Stock , virtual reality, parallel computing, and manipulation of large spatial data sets. As an artist, he creates . Stock built the SUNLIGHT artwork that is installed on the Webb Building in downtown Denver. In addition

The shape of early persistent slip markings in fatigued 316L steel

Czech Academy of Sciences Publication Activity Database

Polák, Jaroslav; Kuběna, Ivo; Man, Jiří

2013-01-01

Roč. 564, MARCH (2013), s. 8-12 ISSN 0921-5093 R&D Projects: GA ČR GAP108/10/2371 Institutional support: RVO:68081723 Keywords : Persistent slip marking * Extrusion * Intrusion * fatigue * crack Subject RIV: JL - Materials Fatigue, Friction Mechanics Impact factor: 2.409, year: 2013

Prayer Marks in Immigrants from Bangladesh with Diabetes Who Live in Greece.

Science.gov (United States)

Papadakis, G; Zampelis, T; Michalopoulou, M; Konstantopoulos, K; Rosenberg, T; Chatzipanagiotou, S

2016-02-01

Prayer marks (PMs) are commonly occurring dermatologic changes in muslims who pray and develop over a long period of time as a consequence of repeated and extended pressure. PMs need careful examination especially for patients with diabetes, who are more vulnerable due to predisposing factors such as venous insufficiency and peripheral neuropathy. A total of 166 patients with diabetes (150 males, 16 females) and 65 normal subjects from Bangladesh were examined for the appearance of PMs. Twenty-eight patients (16.9 %) and one normal subject (1.5 %) had PMs. The marks were not itchy or painful and they were observed on the dorsal aspect of the left foot, which was attributed to a more typical prayer position that placed pressure on the left foot. PMs are not a rare clinical entity among muslim patients with diabetes and most clinicians should be aware of it as it can be the predominant cause of an ulcer.

Gender-marked age stereotypes in english proverbs and sayings

OpenAIRE

Галапчук-Тарнавська, Олена Михайлівна; Halapchuk-Tarnavska, Olena M.

2014-01-01

Gender stereotypes are characteristic features of male/female gender group behavior that are expected by a society.Gender stereotypes in the Ukrainian language are viewed as ethnic stereotypes and perform the function of accumulating and systemizing the social, cultural and historical experiences of the Ukrainian people.Gender-marked age stereotypes are widely accepted believes held about certain age that are perceived as being appropriate for women and men.Family roles are also subject to ch...

Evaluation of TRIGA Mark II reactor in Turkey

International Nuclear Information System (INIS)

Bilge, Ali Nezihi

1990-01-01

There are two research reactors in Turkey and one of them is the university Triga Mark II reactor which was in service since 1979 both for education and industrial application purposes. The main aim of this paper is to evaluate the spectrum of the services carried by Turkish Triga Mark II reactor. In this work, statistical distribution of the graduate works and applications, by using Triga Mark II reactor is examined and evaluated. In addition to this, technical and scientific uses of this above mentioned reactor are also investigated. It was already showed that the uses and benefits of this reactor can not be limited. If the sufficient work and service is given, NDT and industrial applications can also be carried economically. (orig.)

Mechanisms for Limiting Trade Mark Rights to Further Competition and Free Speech

DEFF Research Database (Denmark)

Ramsey, Lisa P; Schovsbo, Jens Hemmingsen

2013-01-01

This article evaluates the different mechanisms that nations use to limit trade mark rights to promote competition, free speech, and other public interests. It shows how EU and US trade mark laws seem to be converging towards a similar model which includes both (1) specific statutory defenses...... of these mechanisms for limiting trade mark rights to better protect the public interest in trade mark disputes. Finally, a proposal for reform is suggested. It consists of three parts: (1) domestic legislatures should revise their trade mark statutes to add more mandatory and specific limitations on trade mark...... to trade mark violations and (2) trade mark doctrines which give courts flexibility to permit unauthorized uses of marks that further the legitimate interests of the accused infringer and the public. Such a development should be welcomed and the article urges other nations to consider adopting one or both...

Regulation of glucose homeostasis by KSR1 and MARK2.

Directory of Open Access Journals (Sweden)

Paula J Klutho

Full Text Available Protein scaffolds control the intensity and duration of signaling and dictate the specificity of signaling through MAP kinase pathways. KSR1 is a molecular scaffold of the Raf/MEK/ERK MAP kinase cascade that regulates the intensity and duration of ERK activation. Relative to wild-type mice, ksr1⁻/⁻ mice are modestly glucose intolerant, but show a normal response to exogenous insulin. However, ksr1⁻/⁻ mice also demonstrate a three-fold increase in serum insulin levels in response to a glucose challenge, suggesting a role for KSR1 in insulin secretion. The kinase MARK2 is closely related to C-TAK1, a known regulator of KSR1. Mice lacking MARK2 have an increased rate of glucose disposal in response to exogenous insulin, increased glucose tolerance, and are resistant to diet-induced obesity. mark2⁻/⁻ksr1⁻/⁻ (DKO mice were compared to wild type, mark2⁻/⁻, and ksr1⁻/⁻ mice for their ability to regulate glucose homeostasis. Here we show that disruption of KSR1 in mark2⁻/⁻ mice reverses the increased sensitivity to exogenous insulin resulting from MARK2 deletion. DKO mice respond to exogenous insulin similarly to wild type and ksr1⁻/⁻ mice. These data suggest a model whereby MARK2 negatively regulates insulin sensitivity in peripheral tissue through inhibition of KSR1. Consistent with this model, we found that MARK2 binds and phosphorylates KSR1 on Ser392. Phosphorylation of Ser392 is a critical regulator of KSR1 stability, subcellular location, and ERK activation. These data reveal an unexpected role for the molecular scaffold KSR1 in insulin-regulated glucose metabolism.

Mice with cancer-induced bone pain show a marked decline in day/night activity.

Science.gov (United States)

Majuta, Lisa A; Guedon, Jean-Marc G; Mitchell, Stefanie A T; Kuskowski, Michael A; Mantyh, Patrick W

2017-09-01

Cancer-induced bone pain (CIBP) is the most common type of pain with cancer. In humans, this pain can be difficult to control and highly disabling. A major problem with CIBP in humans is that it increases on weight-bearing and/or movement of a tumor-bearing bone limiting the activity and functional status of the patient. Currently, there is less data concerning whether similar negative changes in activity occur in rodent models of CIBP. To determine whether there are marked changes in activity in a rodent model of CIBP and compare this to changes in skin hypersensitivity. Osteosarcoma cells were injected and confined to 1 femur of the adult male mouse. Every 7 days, spontaneous horizontal and vertical activities were assessed over a 20-hour day and night period using automated activity boxes. Mechanical hypersensitivity of the hind paw skin was assessed using von Frey testing. As the tumor cells grew within the femur, there was a significant decline in horizontal and vertical activity during the times of the day/night when the mice are normally most active. Mice also developed significant hypersensitivity in the skin of the hind paw in the tumor-bearing limb. Even when the tumor is confined to a single load-bearing bone, CIBP drives a significant loss of activity, which increases with disease progression. Understanding the mechanisms that drive this reduction in activity may allow the development of therapies that allow CIBP patients to better maintain their activity and functional status.

Scent marking in a territorial African antelope: I. The maintenance of borders between male oribi.

Science.gov (United States)

Brashares; Arcese

1999-01-01

Scent marking is ubiquitous among the dwarf antelope and gazelles of Africa, but its function has been the subject of debate. This study examined preorbital gland scent marking in the oribi, Ourebia ourebi, a territorial African antelope. Several hypotheses for the function of scent marking by territorial antelope were tested with observational data. Of these, the hypotheses that scent marking is driven by intrasexual competition between neighbouring males, and that marks serve as an honest advertisement of a male's ability to defend his territory from rivals, were supported best. Thirty-three territorial male oribi on 23 territories marked most at borders shared with other territorial males, and territorial males marked more often at borders shared with multimale groups than at borders shared with a single male. This suggests that males perceived neighbouring male groups as a greater threat to territory ownership than neighbouring males that defended their territories without the aid of adult subordinates. Marking rate was unrelated to territory size or the number of females on adjacent territories, but males with many male neighbours marked at higher rates than those with fewer male neighbours. These results suggest that the presence of male neighbours has a greater effect on the scent marking behaviour of territorial antelope than has been considered previously. Copyright 1999 The Association for the Study of Animal Behaviour.

Monopoly, Pareto and Ramsey mark-ups

NARCIS (Netherlands)

Ten Raa, T.

2009-01-01

Monopoly prices are too high. It is a price level problem, in the sense that the relative mark-ups have Ramsey optimal proportions, at least for independent constant elasticity demands. I show that this feature of monopoly prices breaks down the moment one demand is replaced by the textbook linear

Transcription factors, coregulators, and epigenetic marks are linearly correlated and highly redundant.

Directory of Open Access Journals (Sweden)

Tobias Ahsendorf

Full Text Available The DNA microstates that regulate transcription include sequence-specific transcription factors (TFs, coregulatory complexes, nucleosomes, histone modifications, DNA methylation, and parts of the three-dimensional architecture of genomes, which could create an enormous combinatorial complexity across the genome. However, many proteins and epigenetic marks are known to colocalize, suggesting that the information content encoded in these marks can be compressed. It has so far proved difficult to understand this compression in a systematic and quantitative manner. Here, we show that simple linear models can reliably predict the data generated by the ENCODE and Roadmap Epigenomics consortia. Further, we demonstrate that a small number of marks can predict all other marks with high average correlation across the genome, systematically revealing the substantial information compression that is present in different cell lines. We find that the linear models for activating marks are typically cell line-independent, while those for silencing marks are predominantly cell line-specific. Of particular note, a nuclear receptor corepressor, transducin beta-like 1 X-linked receptor 1 (TBLR1, was highly predictive of other marks in two hematopoietic cell lines. The methodology presented here shows how the potentially vast complexity of TFs, coregulators, and epigenetic marks at eukaryotic genes is highly redundant and that the information present can be compressed onto a much smaller subset of marks. These findings could be used to efficiently characterize cell lines and tissues based on a small number of diagnostic marks and suggest how the DNA microstates, which regulate the expression of individual genes, can be specified.

Experimental research on the effectiveness and adaptability of speed reduction markings in downhill sections on urban roads: a driving simulation study.

Science.gov (United States)

Ding, Han; Zhao, Xiaohua; Rong, Jian; Ma, Jianming

2015-02-01

The objective of this paper is to test the effectiveness and adaptability of speed reduction markings (SRMs) in downhill sections on urban roads with distinct roadway grades. Empirical data including vehicle speed and acceleration were collected in a driving simulator. Subjective questionnaires were conducted, and two indexes - the relative speed difference and standard deviation of acceleration - were developed to evaluate the effectiveness and adaptability of SRMs. Meanwhile, the effectiveness of driving simulator related to different road alignments and types of SRMs has been validated through a field test. Results of subjective questionnaires showed that the majority of subjects had no feelings of nervousness, but they were affected by SRMs while driving through downhill sections in all four scenarios (i.e., downhill sections with vertical grades of 3, 2, 1.5 and 1%). In terms of vehicle speed and acceleration, the results of the analysis of variance (ANOVA) and the contrast analysis (S-N-K method) indicated that SRMs were significantly effective when roadway grades of downgrade sections were 1.5, 2 and 3%, while transverse speed reduction markings (TSRMs) had significantly worse adaptability (P<0.05). Therefore, this research recommends that TSRMs could be placed in downhill sections with roadway grades of 1.5 or 2%; longitudinal speed reduction markings (LSRMs) could be placed in downhill sections with a roadway grade of 3%. Whether SRMs are placed in downhill sections with a roadway grade of 1% would depend on other factors such as financial issues and crash records, which are not considered in this paper. Copyright © 2014 Elsevier Ltd. All rights reserved.

Size-Resolved Penetration of Filtering Materials from CE-Marked Filtering Facepiece Respirators.

Czech Academy of Sciences Publication Activity Database

Serfozo, N.; Ondráček, Jakub; Zíková, Naděžda; Lazaridis, M.; Ždímal, Vladimír

2017-01-01

Roč. 17, č. 5 (2017), s. 1305-1315 ISSN 1680-8584 EU Projects: European Commission(XE) 315760 - HEXACOMM Institutional support: RVO:67985858 Keywords : size-resolved penetration * CE-marked respirator * monodisperse ammonium sulfate Subject RIV: DI - Air Pollution ; Quality OBOR OECD: Environmental sciences (social aspects to be 5.7) Impact factor: 2.606, year: 2016

Cold thyroid nodules show a marked increase in proliferation markers.

Science.gov (United States)

Krohn, Knut; Stricker, Ingo; Emmrich, Peter; Paschke, Ralf

2003-06-01

Thyroid follicular adenomas and adenomatous thyroid nodules are a frequent finding in geographical areas with iodine deficiency. They occur as hypofunctioning (scintigraphically cold) or hyperfunctioning (scintigraphically hot) nodules. Their predominant clonal origin suggests that they result from clonal expansion of a single cell, which is very likely the result of a prolonged increase in proliferation compared with non-affected surrounding cells. To test whether increased cell proliferation is detectable in cold thyroid nodules, we studied paraffin-embedded tissue from 40 cold thyroid nodules and their surrounding normal thyroid tissue for the occurrence of the proliferating cell nuclear antigen (PCNA) and Ki-67 (MIB-1 antibody) epitopes as markers for cell proliferation. All 40 thyroid nodules were histologically well characterized and have been studied for molecular characteristics before. The labeling index (number of labeled cells versus total cell number) for nodular and surrounding tissue was calculated. In 33 cold thyroid nodules a significant (p thyroid nodules a significant (p thyroid epithelial cell proliferation is a uniform feature common to most cold nodules. However, the increase of proliferation markers shows a heterogeneity that is not correlated with histopathologic, molecular, or clinical characteristics.

Ultrafast lasers for precise and corrosion free marking on chirurgical steels

Science.gov (United States)

Neugebauer, Christoph; Aalderink, Dennis; Maurer, Erich; Faisst, Birgit; Budnicki, Aleksander

2017-02-01

The unique properties of ultrashort laser pulses and the decrease of invest pave the way to numerous novel applications. Even in the very price sensitive field of laser marking, ultrashort laser can compete due to a new cost structure and remarkable properties of the marking results. In this study we concentrated on industrial marking of medical equipment by using IR ultrashort lasers and compared the results with common marking laser systems. We demonstrate the benefits of ultrashort lasers marking on chirurgical devices, observing the influence of pulse energy, pulse duration, scanning velocity in respect to the visibility, corrosion resistance and long term durability under clinical conditions. Nowadays many parts and products are marked for the purpose of identification and traceability. One kind of laser marking is the well known annealing of stainless steel by nanosecond marking lasers. When annealing occurs a colored oxide layer grows due to the local heating of the material surface. Compared to the raw material, the annealed marking shows increased corrosion sensitivity. Regarding the traceability, the poor durability of the ns marking resulting in contrast reduction and the corrosion susceptibility are a huge problem. Therefore three different laser sources with ns-psfs pulse duration were observed. The focus rests on the realization of parameter studies (various lasers) and their effect on the corrosion and passivation behavior. Furthermore analysis of the oxide layers by use of EDX and XRD were performed to obtain further information on the composition and structure of the markings.

Quantum Query Complexity for Searching Multiple Marked States from an Unsorted Database

International Nuclear Information System (INIS)

Shang Bin

2007-01-01

An important and usual sort of search problems is to find all marked states from an unsorted database with a large number of states. Grover's original quantum search algorithm is for finding single marked state with uncertainty, and it has been generalized to the case of multiple marked states, as well as been modified to find single marked state with certainty. However, the query complexity for finding all multiple marked states has not been addressed. We use a generalized Long's algorithm with high precision to solve such a problem. We calculate the approximate query complexity, which increases with the number of marked states and with the precision that we demand. In the end we introduce an algorithm for the problem on a 'duality computer' and show its advantage over other algorithms.

46 CFR 185.602 - Hull markings.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Hull markings. 185.602 Section 185.602 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) OPERATIONS Markings Required § 185.602 Hull markings. (a) Each vessel must be marked as required by part 67...

DRAWING FOR TRAFFIC MARKING USING BIDIRECTIONAL GRADIENT-BASED DETECTION WITH MMS LIDAR INTENSITY

Directory of Open Access Journals (Sweden)

G. Takahashi

2016-06-01

Full Text Available Recently, the development of autonomous cars is accelerating on the integration of highly advanced artificial intelligence, which increases demand for a digital map with high accuracy. In particular, traffic markings are required to be precisely digitized since automatic driving utilizes them for position detection. To draw traffic markings, we benefit from Mobile Mapping Systems (MMS equipped with high-density Laser imaging Detection and Ranging (LiDAR scanners, which produces large amount of data efficiently with XYZ coordination along with reflectance intensity. Digitizing this data, on the other hand, conventionally has been dependent on human operation, which thus suffers from human errors, subjectivity errors, and low reproductivity. We have tackled this problem by means of automatic extraction of traffic marking, which partially accomplished to draw several traffic markings (G. Takahashi et al., 2014. The key idea of the method was extracting lines using the Hough transform strategically focused on changes in local reflection intensity along scan lines. However, it failed to extract traffic markings properly in a densely marked area, especially when local changing points are close each other. In this paper, we propose a bidirectional gradient-based detection method where local changing points are labelled with plus or minus group. Given that each label corresponds to the boundary between traffic markings and background, we can identify traffic markings explicitly, meaning traffic lines are differentiated correctly by the proposed method. As such, our automated method, a highly accurate and non-human-operator-dependent method using bidirectional gradient-based algorithm, can successfully extract traffic lines composed of complex shapes such as a cross walk, resulting in minimizing cost and obtaining highly accurate results.

Drawing for Traffic Marking Using Bidirectional Gradient-Based Detection with MMS LIDAR Intensity

Science.gov (United States)

Takahashi, G.; Takeda, H.; Nakamura, K.

2016-06-01

Recently, the development of autonomous cars is accelerating on the integration of highly advanced artificial intelligence, which increases demand for a digital map with high accuracy. In particular, traffic markings are required to be precisely digitized since automatic driving utilizes them for position detection. To draw traffic markings, we benefit from Mobile Mapping Systems (MMS) equipped with high-density Laser imaging Detection and Ranging (LiDAR) scanners, which produces large amount of data efficiently with XYZ coordination along with reflectance intensity. Digitizing this data, on the other hand, conventionally has been dependent on human operation, which thus suffers from human errors, subjectivity errors, and low reproductivity. We have tackled this problem by means of automatic extraction of traffic marking, which partially accomplished to draw several traffic markings (G. Takahashi et al., 2014). The key idea of the method was extracting lines using the Hough transform strategically focused on changes in local reflection intensity along scan lines. However, it failed to extract traffic markings properly in a densely marked area, especially when local changing points are close each other. In this paper, we propose a bidirectional gradient-based detection method where local changing points are labelled with plus or minus group. Given that each label corresponds to the boundary between traffic markings and background, we can identify traffic markings explicitly, meaning traffic lines are differentiated correctly by the proposed method. As such, our automated method, a highly accurate and non-human-operator-dependent method using bidirectional gradient-based algorithm, can successfully extract traffic lines composed of complex shapes such as a cross walk, resulting in minimizing cost and obtaining highly accurate results.

Subjectivity, individuality and singularity in children: a socially constituted subject

Directory of Open Access Journals (Sweden)

Alessandra Del Ré

2012-11-01

Full Text Available Considering the hypothesis that Bakhtin and his Circle‟s reflections can help us think about issues involving the field of Language Acquisition, in addition to the fact that there are only a few works developed within this perspective in Brazil, in this article, we intend to discuss the notions of “subject”, “subjectivity”,“individuality” and “singularity”, drawing on Bakhtin‟s theory. Thus, in order to make this discussion clearer, we bring data from the speech of young children, from 1.8 to 3 years old, who were filmed in natural contexts interacting with their parents and relatives. From these data, we could verify, among other things, that children, as individuals who constitute themselves as subjects in and throughlanguage, bring marks to their discourse, revealing their subjectivity (through lexical, morphological, syntactic or genre choices.

Mark Kostabi soovib muuta inimesi õnnelikumaks / Kalev Mark Kostabi

Index Scriptorium Estoniae

Kostabi, Kalev Mark, 1960-

2008-01-01

Kalev Mark Kostabi oma sisekujunduslikest eelistustest, ameeriklaste ja itaallaste kodude sisekujunduse erinevustest, kunstist kui ruumikujunduse ühest osast, oma New Yorgi ja Rooma korterite kujundusest

Linguistic constraints on children's overt marking of BE by dialect and age.

Science.gov (United States)

Roy, Joseph; Oetting, Janna B; Moland, Christy Wynn

2013-06-01

Overt marking of BE in nonmainstream adult dialects of English is influenced by a number of linguistic constraints, including the structure's person, number, tense, contractibility, and grammatical function. In the current study, the authors examined the effects of these constraints on overt marking of BE in children as a function of their nonmainstream English dialect and age. The data were language samples from 62 children, ages 4-6 years; 24 children spoke African American English (AAE), and 38 spoke Southern White English (SWE). Analyses included analysis of variance and logistic regression. Rates of overt marking varied by the children's dialect but not their age. Although the person, number, tense, and grammatical function of BE influenced the children's rates of marking, the nature and magnitude of the influence differed by the children's dialect. For AAE-speaking children, contractibility also influenced their marking of BE. Consistent with the adult literature, the current study showed that AAE- and SWE-speaking children marked BE in ways that differed from each other and from what has been documented for child speakers of Mainstream American English. These findings show stability in the use of BE in AAE and SWE that spans different generations and different dialect communities.

Surface laser marking optimization using an experimental design approach

Science.gov (United States)

Brihmat-Hamadi, F.; Amara, E. H.; Lavisse, L.; Jouvard, J. M.; Cicala, E.; Kellou, H.

2017-04-01

Laser surface marking is performed on a titanium substrate using a pulsed frequency doubled Nd:YAG laser ( λ= 532 nm, τ pulse=5 ns) to process the substrate surface under normal atmospheric conditions. The aim of the work is to investigate, following experimental and statistical approaches, the correlation between the process parameters and the response variables (output), using a Design of Experiment method (DOE): Taguchi methodology and a response surface methodology (RSM). A design is first created using MINTAB program, and then the laser marking process is performed according to the planned design. The response variables; surface roughness and surface reflectance were measured for each sample, and incorporated into the design matrix. The results are then analyzed and the RSM model is developed and verified for predicting the process output for the given set of process parameters values. The analysis shows that the laser beam scanning speed is the most influential operating factor followed by the laser pumping intensity during marking, while the other factors show complex influences on the objective functions.

27 CFR 28.193 - Export marks.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.193... Drawback Filing of Notice and Removal § 28.193 Export marks. In addition to the marks and brands required... chapter, the exporter shall mark the word “Export” on the Government side of each case or Government head...

27 CFR 28.103 - Export marks.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.103... Manufacturing Bonded Warehouse § 28.103 Export marks. (a) General. In addition to the marks and brands required... provisions of part 19 of this chapter, the proprietor shall mark the word “Export” on the Government side of...

27 CFR 28.144 - Export marks.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.144... § 28.144 Export marks. (a) General Requirement. In addition to the marks and brands required to be... brewer shall mark the word “Export” on each container or case of beer, or the words “Beer concentrate for...

27 CFR 28.154 - Export marks.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.154..., for Exportation or Transfer to a Foreign-Trade Zone § 28.154 Export marks. In addition to the marks... provisions of part 19 of this chapter, the proprietor shall mark the word “Export” on the Government side of...

1L Mark-IV Target Design Review

Energy Technology Data Exchange (ETDEWEB)

Koehler, Paul E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2017-11-16

This presentation includes General Design Considerations; Current (Mark-III) Lower Tier; Mark-III Upper Tier; Performance Metrics; General Improvements for Material Science; General Improvements for Nuclear Science; Improving FOM for Nuclear Science; General Design Considerations Summary; Design Optimization Studies; Expected Mark-IV Performance: Material Science; Expected Mark-IV Performance: Nuclear Science (Disk); Mark IV Enables Much Wider Range of Nuclear-Science FOM Gains than Mark III; Mark-IV Performance Summary; Rod or Disk? Center or Real FOV?; and Project Cost and Schedule.

High contrast laser marking of alumina

International Nuclear Information System (INIS)

Penide, J.; Quintero, F.; Riveiro, A.; Fernández, A.; Val, J. del; Comesaña, R.; Lusquiños, F.; Pou, J.

2015-01-01

Highlights: • Laser marking of alumina using near infrared (NIR) lasers was experimentally analyzed. • Color change produced by NIR lasers is due to thermally induced oxygen vacancies. • Laser marking results obtained using NIR lasers and green laser are compared. • High contrast marks on alumina were achieved. - Abstract: Alumina serves as raw material for a broad range of advanced ceramic products. These elements should usually be identified by some characters or symbols printed directly on them. In this sense, laser marking is an efficient, reliable and widely implemented process in industry. However, laser marking of alumina still leads to poor results since the process is not able to produce a dark mark, yielding bad contrast. In this paper, we present an experimental study on the process of marking alumina by three different lasers working in two wavelengths: 1064 nm (Near-infrared) and 532 nm (visible, green radiation). A colorimetric analysis has been carried out in order to compare the resulting marks and its contrast. The most suitable laser operating conditions were also defined and are reported here. Moreover, the physical process of marking by NIR lasers is discussed in detail. Field Emission Scanning Electron Microscopy, High Resolution Transmission Electron Microscopy and X-ray Photoelectron Spectroscopy were also employed to analyze the results. Finally, we propose an explanation for the differences of the coloration induced under different atmospheres and laser parameters. We concluded that the atmosphere is the key parameter, being the inert one the best choice to produce the darkest marks

Changing Context of Trade Mark Protection in India: A Review of the Trade Marks Act, 1999

OpenAIRE

Pathak, Akhileshwar

2004-01-01

With liberalisation and globalisation of the Indian economy, it has become possible for anyone to get into production and services in most of the sectors. This has led to rampant misuse and appropriation of trade marks. In an insulated economy, with monopoly markets, law protecting trade marks had a limited role. In the changed context, however, trade mark law will be a field of much interest for academics and practitioners. Towards this, the paper explores the formation of trade mark law in ...

Combined pump and marking tests for determining protection zones

Energy Technology Data Exchange (ETDEWEB)

Hoetzl, H.; Brauns, J.

1982-02-01

Under difficult conditions the determination of the protection area II on the basis of Mear pump tests becomes uncertain. The report shows how in such cases the results of supplementary marking tests can establish a more accurate finding. The execution of combined pump and marking tests enables us to check data gained on a theoretical basis and possibly alter these. This method is described in an example, in which certain hydrogeological conditions and rival interests of ground water protection prevail on the one side and utilization of land on the other side. A general tendency exists to take the utmost protective measure in safeguarding ground water, however in cases of collision of interests the boundary of the protective area should be optimized. Supplementary marking tests can be of great significance.

Experimental applications for the MARK-1 and MARK-1A pulsed ionizing radiation detection systems. Volume 3

International Nuclear Information System (INIS)

Harker, Y.D.; Lawrence, R.S.; Yoon, W.Y.; Lones, J.L.

1993-12-01

This report is the third volume in a three volume set describing the MARK series of pulsed ionizing radiation detection systems. This volume describes the MARK-1A detection system, compares it with the MARK-1 system, and describes the experimental testing of the detection systems. Volume 1 of this set presents the technical specifications for the MARK-1 detection system. Volume 2 is an operations manual specifically for the MARK-1 system, but it generally applies to the MARK-1A system as well. These detection systems operate remotely and detect photon radiation from a single or a multiple pulsed source. They contain multiple detector (eight in the MARK-1 and ten in the MARK-1A) for determination of does and incident photon effective energy. The multiple detector arrangement, having different detector sizes and shield thicknesses, provides the capability of determining the effective photon energy of the radiation spectrum. Dose measurements using these units are consistent with TLD measurements. The detection range is from 3 nanorads to 90 microrads per source burst; the response is linear over that range. Three units were built and are ready for field deployment

Mirror-mark tests performed on jackdaws reveal potential methodological problems in the use of stickers in avian mark-test studies.

Directory of Open Access Journals (Sweden)

Manuel Soler

Full Text Available Some animals are capable of recognizing themselves in a mirror, which is considered to be demonstrated by passing the mark test. Mirror self-recognition capacity has been found in just a few mammals having very large brains and only in one bird, the magpie (Pica pica. The results obtained in magpies have enormous biological and cognitive implications because the fact that magpies were able to pass the mark test meant that this species is at the same cognitive level with great apes, that mirror self-recognition has evolved independently in the magpie and great apes (which diverged 300 million years ago, and that the neocortex (which is not present in the bird's brains is not a prerequisite for mirror self-recognition as previously believed. Here, we have replicated the experimental design used on magpies to determine whether jackdaws (Corvus monedula are also capable of mirror self-recognition by passing the mark test. We found that our nine jackdaws showed a very high interest towards the mirror and exhibited self-contingent behavior as soon as mirrors were introduced. However, jackdaws were not able to pass the mark test: both sticker-directed actions and sticker removal were performed with a similar frequency in both the cardboard (control and the mirror conditions. We conclude that our jackdaws' behaviour raises non-trivial questions about the methodology used in the avian mark test. Our study suggests that the use of self-adhesive stickers on sensitive throat feathers may open the way to artefactual results because birds might perceive the stickers tactilely.

Evalution of the diet of a carabid predator using fluorescent marking of prey

Czech Academy of Sciences Publication Activity Database

Okrouhlík, Jan; Foltan, Pavel

2015-01-01

Roč. 112, č. 3 (2015), s. 477-485 ISSN 1210-5759 Grant - others:GA ČR(CZ) GA526/09/1249 Institutional support: RVO:60077344 Keywords : food web * prey marking * fluorescent dye Subject RIV: EH - Ecology, Behaviour Impact factor: 0.975, year: 2014 http://www.eje.cz/pdfs/eje/2015/03/11.pdf

Augmented marked graphs

CERN Document Server

Cheung, King Sing

2014-01-01

Petri nets are a formal and theoretically rich model for the modelling and analysis of systems. A subclass of Petri nets, augmented marked graphs possess a structure that is especially desirable for the modelling and analysis of systems with concurrent processes and shared resources.This monograph consists of three parts: Part I provides the conceptual background for readers who have no prior knowledge on Petri nets; Part II elaborates the theory of augmented marked graphs; finally, Part III discusses the application to system integration. The book is suitable as a first self-contained volume

Court presentation of bite mark evidence.

Science.gov (United States)

Drinnan, A J; Melton, M J

1985-12-01

The uniqueness of an individual's bite mark is generally accepted. The use of bite mark analysis to identify or exclude those suspected of crimes is now a well established activity in forensic dentistry. Although the techniques for evaluating bite mark evidence are extremely sophisticated, it is important that the courtroom presentation of such evidence should be as simple as possible and be directed towards those who must judge it. Dentists likely to be involved in the courtroom presentation of bite mark evidence should: be certain that their local law enforcement personnel are frequently updated on the techniques to be used for producing the optimum evidence needed to evaluate bite marks; become acquainted with the current techniques of evaluating bite mark evidence and understand their difficulties and pitfalls; meet with the lawyers (prosecution or defence) before a courtroom appearance, briefing them on the significance of the particular findings; prepare clear and easily understandable visual aids to present to the court the techniques used in the analysis and the bases for the conclusion reached; and offer conclusions derived from the bite mark investigation.

Beyond δ : Tailoring marked statistics to reveal modified gravity

Science.gov (United States)

Valogiannis, Georgios; Bean, Rachel

2018-01-01

Models that seek to explain cosmic acceleration through modifications to general relativity (GR) evade stringent Solar System constraints through a restoring, screening mechanism. Down-weighting the high-density, screened regions in favor of the low density, unscreened ones offers the potential to enhance the amount of information carried in such modified gravity models. In this work, we assess the performance of a new "marked" transformation and perform a systematic comparison with the clipping and logarithmic transformations, in the context of Λ CDM and the symmetron and f (R ) modified gravity models. Performance is measured in terms of the fractional boost in the Fisher information and the signal-to-noise ratio (SNR) for these models relative to the statistics derived from the standard density distribution. We find that all three statistics provide improved Fisher boosts over the basic density statistics. The model parameters for the marked and clipped transformation that best enhance signals and the Fisher boosts are determined. We also show that the mark is useful both as a Fourier and real-space transformation; a marked correlation function also enhances the SNR relative to the standard correlation function, and can on mildly nonlinear scales show a significant difference between the Λ CDM and the modified gravity models. Our results demonstrate how a series of simple analytical transformations could dramatically increase the predicted information extracted on deviations from GR, from large-scale surveys, and give the prospect for a much more feasible potential detection.

The efficacy of mass-marking channel catfish fingerlings by immersion in oxytetracycline

Science.gov (United States)

Stewart, David R.

2011-01-01

Oxytetracycline (OTC) has been extensively used for marking a variety of fish species, but has never been successfully used to mark channel catfish Ictalurus punctatus. Channel catfish fingerlings (~ 25 mm TL) obtained from the Oklahoma Department of Wildlife Conservation at Byron Fish Hatchery were kept in Living Streams (791 to 1,018 L) equipped with recirculation units. Marking trials consisted of immersing channel catfish in one of three concentrations (250, 450, and 700 mg/L) OTC hydrochloride [HCl] for 6 hours. Samples of channel catfish were obtained from each group at 1-week and 4-week postimmersion. Lapilli otoliths and pectoral spines were removed to assess mark presence with an epi-fluorescent compound microscope. After one week, no marks were detected on pectoral spines for all treatments, mark detection on otoliths depended on concentration, but never exceeded 43% (700 mg/L). After four weeks, all otoliths and pectoral spines were determined marked for 700 mg/L OTC, 20% for fish immersed in 450 mg/L OTC, and 0% were marked after four weeks at the 250 mg/L OTC. Results show, channel catfish fingerlings can be successfully marked with immersion in OTC at 700 mg/L for at least 6 hours.

A Trust-Based Adaptive Probability Marking and Storage Traceback Scheme for WSNs

Science.gov (United States)

Liu, Anfeng; Liu, Xiao; Long, Jun

2016-01-01

Security is a pivotal issue for wireless sensor networks (WSNs), which are emerging as a promising platform that enables a wide range of military, scientific, industrial and commercial applications. Traceback, a key cyber-forensics technology, can play an important role in tracing and locating a malicious source to guarantee cybersecurity. In this work a trust-based adaptive probability marking and storage (TAPMS) traceback scheme is proposed to enhance security for WSNs. In a TAPMS scheme, the marking probability is adaptively adjusted according to the security requirements of the network and can substantially reduce the number of marking tuples and improve network lifetime. More importantly, a high trust node is selected to store marking tuples, which can avoid the problem of marking information being lost. Experimental results show that the total number of marking tuples can be reduced in a TAPMS scheme, thus improving network lifetime. At the same time, since the marking tuples are stored in high trust nodes, storage reliability can be guaranteed, and the traceback time can be reduced by more than 80%. PMID:27043566

Nuclear particle track-etched anti-bogus mark

International Nuclear Information System (INIS)

He Xiangming; Yan Yushun; Zhang Quanrong

2003-01-01

Nuclear particle track-etched anti-bogus mark is a new type of forgery-proof product after engraving gravure printing, thermocolour, fluorescence, laser hologram and metal concealed anti-bogus mark. The mark is manufactured by intricate high technology and the state strictly controlled sensitive nuclear facilities to ensure the mark not to be copied. The pattern of the mark is specially characterized by permeability of liquid to be discriminated from forgery. The genuine mark can be distinguished from sham one by transparent liquid (e.g. water), colorful pen and chemical reagent. The mark has passed the official examination of health safety. It is no danger of nuclear irradiation. (author)

Literature study on the state-of-the-art for the marking of deep geological repositories for radioactive wastes

International Nuclear Information System (INIS)

Buser, M.

2010-05-01

This comprehensive report for the Swiss Federal Office of Energy (SFOE) summarises the results of a literature study on the marking of repositories for radioactive wastes. Knowledge gained and ideas discussed in Switzerland on the subject are collated and discussed. Various associated topics such as safety, risk and marking technologies are examined. 28 topics in six thematic blocks are presented and discussed. Not only marking concepts are discussed, but also questions on human and society-related factors, traditionalising information transfer and susceptibility to wrong interpretation are examined. The author is of the opinion that no reusable materials be used either in the repositories themselves or for their marking in order to help prevent future generations coming into contact with the dangerous wastes

High efficiency metal marking with CO2 laser and glass marking with excimer laser

DEFF Research Database (Denmark)

Bastue, Jens; Olsen, Flemmming Ove

1997-01-01

with a thoroughly tested ray-tracing model is presented and compared with experimental results. Special emphasis is put on two different applications namely marking in metal with TEA-CO2 laser and marking in glass with excimer laser. The results are evaluated on the basis of the achievable energy enhancement......Today, mask based laser materials processing and especially marking is widely used. However, the energy efficiency in such processes is very low [1].This paper gives a review of the results, that may be obtained using the energy enhancing technique [1]. Results of simulations performed...

Electronic Repositories of Marked Student Work and their Contributions to Formative Evaluation

Directory of Open Access Journals (Sweden)

Eva Heinrich

2004-07-01

Full Text Available The educational literature shows that formative assessment is highly conducive to learning. The tasks given to students in formative assessment generally require open-ended responses that can be given, for example, in essay-type format and that are assessed by a human marker. An essential component is the formative feedback provided by the marker that needs to assist the student in recognising knowledge gaps and in formulating steps to close these gaps. The concepts of ‘electronic repositories of marked student work’ introduced in this article suggests an approach to support learning from formative assessment. At the core of this concept lies the realisation that the artefacts submitted by students and assessed by markers are a valuable resource. This resource should not just be used by the submitting students but should be made accessible to future students studying the same concepts. These students can learn from the artefacts and the formative feedback attached to these artefacts. Self- and peer-assessment, important concepts closely linked to formative assessment, can be integrated with the repositories to develop the students’ subject knowledge, to enhance their critical thinking skills and to familiarise them with assessment procedures. This article develops the concepts of electronic repositories of marked student work. Special emphasis is put on reviewing the educational literature on formative assessment and on binding the concepts introduced into the literature findings.

Assessment of severe accident prevention and mitigation features: BWR, Mark II containment design

International Nuclear Information System (INIS)

Lehner, J.R.; Hsu, C.J.; Eltawila, F.; Perkins, K.R.; Luckas, W.J.; Fitzpatrick, R.G.; Pratt, W.T.

1988-07-01

Plant features and operator actions, which have been found to be important in either preventing or mitigating severe accidents in BWRs with Mark II containments (BWR Mark II's) have been identified. These features and actions were developed from insights derived from reviews of in-depth risk assessments performed specifically for the Limerick and Shoreham plants and from other relevant studies. Accident sequences that dominate the core-damage frequency and those accident sequences that are of potentially high consequence were identified. Vulnerabilities of the BWR Mark II to severe-accident containment loads were also noted. In addition, those features of a BWR Mark II, which are important for preventing core damage and are available for mitigating fission-product release to the environment were also identified. This report is issued to provide focus to an analyst examining an individual plant. This report calls attention to plant features and operator actions and provides a list of deterministic attributes for assessing those features and actions found to be helpful in reducing the overall risk for Mark II plants. Thus, the guidance is offered as a resource in examining the subject plant to determine if the same, or similar, plant features and operator actions will be of value in reducing overall plant risk. This report is intended to serve solely as guidance

Plasma and serum lipidomics of healthy white adults shows characteristic profiles by subjects' gender and age.

Directory of Open Access Journals (Sweden)

Masaki Ishikawa

Full Text Available Blood is a commonly used biofluid for biomarker discovery. Although blood lipid metabolites are considered to be potential biomarker candidates, their fundamental properties are not well characterized. We aimed to (1 investigate the matrix type (serum vs. plasma that may be preferable for lipid biomarker exploration, (2 elucidate age- and gender-associated differences in lipid metabolite levels, and (3 examine the stability of lipid metabolites in matrix samples subjected to repeated freeze-thaw cycles. Using liquid chromatography-mass spectrometry, we performed lipidomic analyses for fasting plasma and serum samples for four groups (15 subjects/group of young and elderly (25-34 and 55-64 years old, respectively males and females and for an additional aliquot of samples from young males, which were subjected to repeated freeze-thaw cycles. Lysophosphatidylcholine and diacylglycerol levels were higher in serum than in plasma samples, suggesting that the clotting process influences serum lipid metabolite levels. Gender-associated differences highlighted that the levels of many sphingomyelin species were significantly higher in females than in males, irrespective of age and matrix (plasma and serum. Age-associated differences were more prominent in females than in males, and in both matrices, levels of many triacylglycerols were significantly higher in elderly females than in young females. Plasma and serum levels of most lipid metabolites were reduced by freeze-thawing. Our results indicate that plasma is an optimal matrix for exploring lipid biomarkers because it represents the original properties of an individual's blood sample. In addition, the levels of some blood lipid species of healthy adults showed gender- and age-associated differences; thus, this should be considered during biomarker exploration and its application in diagnostics. Our fundamental findings on sample selection and handling procedures for measuring blood lipid metabolites

MARK/Par1 Kinase Is Activated Downstream of NMDA Receptors through a PKA-Dependent Mechanism.

Directory of Open Access Journals (Sweden)

Laura P Bernard

Full Text Available The Par1 kinases, also known as microtubule affinity-regulating kinases (MARKs, are important for the establishment of cell polarity from worms to mammals. Dysregulation of these kinases has been implicated in autism, Alzheimer's disease and cancer. Despite their important function in health and disease, it has been unclear how the activity of MARK/Par1 is regulated by signals from cell surface receptors. Here we show that MARK/Par1 is activated downstream of NMDA receptors in primary hippocampal neurons. Further, we show that this activation is dependent on protein kinase A (PKA, through the phosphorylation of Ser431 of Par4/LKB1, the major upstream kinase of MARK/Par1. Together, our data reveal a novel mechanism by which MARK/Par1 is activated at the neuronal synapse.

27 CFR 19.605 - Additional marks on portable containers.

Science.gov (United States)

2010-04-01

... “Tax-Free.” (b) The proprietor may show other information such as brand or trade name; caution notices... plant control data. However, marks or attachments shall not conceal, obscure, interfere with or conflict...

A Collar for Marking Big Game Animals

Science.gov (United States)

Robert L. Phillips

1970-01-01

A Simple, inexpensive collar made of Armor-tite (a vinyl-coated nylon fabric) was designed for marking white-tailed deer (Odocoileus virginianus) and moose (Alces alces). Field tests showed that the material is easily seen and extrememly durable. It may be suitable for use on other large mammals. The collar can be quickly fitted to individual animals under field...

Protecting the turf: The effect of territorial marking on others' creativity.

Science.gov (United States)

Brown, Graham; Baer, Markus

2015-11-01

Territorial marking allows people to communicate that a territory has been claimed. Across 2 studies, we examine the impact of territorial marking of one's ideas on others' invited creativity when asked to provide feedback. Integrating research on territoriality and self-construal, we examine the effect of control-oriented marking on invited creativity (Study 1), and the extent to which an independent versus interdependent self-construal moderates this effect (Study 2). Results of Study 1 demonstrate that the use of control-oriented marking to communicate a territorial claim over one's ideas inhibits invited creativity, and this effect is mediated by intrinsic motivation. Also consistent with our hypotheses, the results of Study 2 show that self-construal moderates the effect of control-oriented marking on others' intrinsic motivation and creativity. Marking diminishes invited creativity among people with an independent self-construal but serves to enhance the creativity of those with an interdependent self-construal. Consistent with Study 1, intrinsic motivation mediates this moderated effect. Our results highlight the important but heretofore understudied role of territoriality in affecting others' creativity as well as the role of independent versus interdependent self-construal in shaping this effect. (c) 2015 APA, all rights reserved).

Laser marking as a result of applying reverse engineering

Science.gov (United States)

Mihalache, Andrei; Nagîţ, Gheorghe; Rîpanu, Marius Ionuţ; Slǎtineanu, Laurenţiu; Dodun, Oana; Coteaţǎ, Margareta

2018-05-01

The elaboration of a modern manufacturing technology needs a certain quantum of information concerning the part to be obtained. When it is necessary to elaborate the technology for an existing object, such an information could be ensured by using the principles specific to the reverse engineering. Essentially, in the case of this method, the analysis of the surfaces and of other characteristics of the part must offer enough information for the elaboration of the part manufacturing technology. On the other hand, it is known that the laser marking is a processing method able to ensure the transfer of various inscriptions or drawings on a part. Sometimes, the laser marking could be based on the analysis of an existing object, whose image could be used to generate the same object or an improved object. There are many groups of factors able to affect the results of applying the laser marking process. A theoretical analysis was proposed to show that the heights of triangles obtained by means of a CNC marking equipment depend on the width of the line generated by the laser spot on the workpiece surface. An experimental research was thought and materialized to highlight the influence exerted by the line with and the angle of lines intersections on the accuracy of the marking process. By mathematical processing of the experimental results, empirical mathematical models were determined. The power type model and the graphical representation elaborated on the base of this model offered an image concerning the influences exerted by the considered input factors on the marking process accuracy.

Marked QTc prolongation and Torsades de Pointes in patients with chronic inflammatory arthritis

Directory of Open Access Journals (Sweden)

Pietro Enea Lazzerini

2016-09-01

Full Text Available Mounting evidence indicates that in chronic inflammatory arthritis (CIA, QTc prolongation is frequent and correlates with systemic inflammatory activation. Notably, basic studies demonstrated that inflammatory cytokines induce profound changes in potassium and calcium channels resulting in a prolonging effect on cardiomyocyte action potential duration (APD, thus on the QT interval on the electrocardiogram. Moreover, it has been demonstrated that in RA patients the risk of SCD is significantly increased when compared to non-RA subjects. Conversely, to date no data are available about Torsades de Pointes (TdP prevalence in CIA, and the few case reported considered CIA only an incidental concomitant disease, not contributing factor to TdP development.We report three patients with active CIA developing marked QTc prolongation, in two cases complicated with TdP degenerating to cardiac arrest. In these patients, a blood sample was obtained within 24h from TdP/marked QTc prolongation occurrence and levels of IL-6, TNF-alpha and IL-1 were evaluated. In all three cases, IL-6 was markedly elevated, ~10 to 100 times more than reference values. Moreover, one patient also showed high circulating levels of TNF-alpha and IL-1. In conclusion, active CIA may represent a currently overlooked QT-prolonging risk factor, potentially contributing in the presence of other classical risk factors to TdP occurrence. In particular, a relevant role may be played by elevated circulating IL-6 levels via direct electrophysiological effects on the heart. This observation should be carefully kept in mind, particularly when recognizable risk factors are already present and/or the addition of QT-prolonging drugs is required.

Reproducibility of Computer-Aided Detection Marks in Digital Mammography

International Nuclear Information System (INIS)

Kim, Seung Ja; Moon, Woo Kyung; Cho, Nariya; Kim, Sun Mi; Im, Jung Gi; Cha, Joo Hee

2007-01-01

To evaluate the performance and reproducibility of a computeraided detection (CAD) system in mediolateral oblique (MLO) digital mammograms taken serially, without release of breast compression. A CAD system was applied preoperatively to the fulfilled digital mammograms of two MLO views taken without release of breast compression in 82 patients (age range: 33 83 years; mean age: 49 years) with previously diagnosed breast cancers. The total number of visible lesion components in 82 patients was 101: 66 masses and 35 microcalcifications. We analyzed the sensitivity and reproducibility of the CAD marks. The sensitivity of the CAD system for first MLO views was 71% (47/66) for masses and 80% (28/35) for microcalcifications. The sensitivity of the CAD system for second MLO views was 68% (45/66) for masses and 17% (6/35) for microcalcifications. In 84 ipsilateral serial MLO image sets (two patients had bilateral cancers), identical images, regardless of the existence of CAD marks, were obtained for 35% (29/84) and identical images with CAD marks were obtained for 29% (23/78). Identical images, regardless of the existence of CAD marks, for contralateral MLO images were 65% (52/80) and identical images with CAD marks were obtained for 28% (11/39). The reproducibility of CAD marks for the true positive masses in serial MLO views was 84% (42/50) and that for the true positive microcalcifications was 0% (0/34). The CAD system in digital mammograms showed a high sensitivity for detecting masses and microcalcifications. However, reproducibility of microcalcification marks was very low in MLO views taken serially without release of breast compression. Minute positional change and patient movement can alter the images and result in a significant effect on the algorithm utilized by the CAD for detecting microcalcifications

Marked elevation in plasma trimethylamine-N-oxide (TMAO in patients with mitochondrial disorders treated with oral l-carnitine

Directory of Open Access Journals (Sweden)

H.D. Vallance

2018-06-01

Full Text Available Oral supplementation with l-carnitine is a common therapeutic modality for mitochondrial disorders despite limited evidence of efficacy. Recently, a number of studies have demonstrated that a gut microbiota-dependent metabolite of l-carnitine, trimethylamine oxide (TMAO, is an independent and dose-dependent risk factor for cardiovascular disease (CVD. Given the limited data demonstrating efficacy with oral l-carnitine therapy and the newly raised questions of potential harm, we assessed plasma TMAO levels in patients with mitochondrial disease with and without oral l-carnitine supplementation. Nine subjects were recruited and completed the study. Eight out of 9 subjects at baseline had plasma TMAO concentrations <97.5th percentile (<15.5 μM. One subject with stage 3 renal disease, had marked elevation in plasma TMAO (pre 33.98 μm versus post 101.6 μm. Following at least 3 months of l-carnitine supplementation (1000 mg per day, plasma TMAO levels were markedly increased in 7out of 9 subjects; overall, plasma TMAO significantly increased 11.8-fold (p < 0.001 from a baseline median level of 3.54 μm (interquartile range (IQR 2.55–8.72 to 43.26 (IQR 23.99–56.04 post supplementation. The results of this study demonstrate that chronic oral l-carnitine supplementation markedly increases plasma TMAO levels in subjects with mitochondrial disorders. Further studies to evaluate both the efficacy and long term safety of oral l-carnitine supplementation for the treatment of mitochondrial disorders are warranted. Keywords: l-carnitine, Trimethylamine N-oxide, Mitochondrial disorders

46 CFR 160.176-23 - Marking.

Science.gov (United States)

2010-10-01

... of the vessel. (2) The type of vessel. (3) Specific purpose or limitation approved by the Coast Guard...: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Inflatable Lifejackets § 160.176-23 Marking. (a) General. Each inflatable lifejacket must be marked with the information required by this section. Each marking must be...

On-road Bicycle Pavement Markings

Data.gov (United States)

Allegheny County / City of Pittsburgh / Western PA Regional Data Center — A mile by mile breakdown of the on-street bicycle pavement markings installed within the City of Pittsburgh. These include bike lanes, shared lane markings...

Marks of Metal Copenhell

DEFF Research Database (Denmark)

2015-01-01

Planchebaseret udendørs udstilling på musikfestivalen Copenhell 18-20/6 2015. En mindre udgave af udstillingen Marks of Metal - Logodesign og visualitet i heavy metal. Udarbejdet i samarbejde med Mediemuseet.......Planchebaseret udendørs udstilling på musikfestivalen Copenhell 18-20/6 2015. En mindre udgave af udstillingen Marks of Metal - Logodesign og visualitet i heavy metal. Udarbejdet i samarbejde med Mediemuseet....

Circulatory Markings at Double-Lane Traffic Roundabout.

NARCIS (Netherlands)

Bie, Jing; Lo, Hong K.; Wong, S.C.

2008-01-01

This paper compares two types of circulatory markings at a double-lane traffic roundabout: the concentric marking scheme and the Alberta marking scheme. The effects of these two marking schemes on drivers' lane choice behavior, delay, and safety, are compared based on data collected from before and

7 CFR 160.32 - Marking containers.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Marking containers. 160.32 Section 160.32 Agriculture... STANDARDS FOR NAVAL STORES Analysis, Inspection, and Grading on Request § 160.32 Marking containers. The interested person shall provide any labor necessary for marking the containers, after the contents have been...

46 CFR 122.602 - Hull markings.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Hull markings. 122.602 Section 122.602 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150....602 Hull markings. (a) Each vessel must be marked as required by part 67, subpart I, of this chapter...

Stretch Marks

Science.gov (United States)

... completely without the help of a dermatologist or plastic surgeon. These doctors may use one of many types of treatments — from actual surgery to techniques like microdermabrasion and laser treatment — to reduce the appearance of stretch marks. These techniques are ...

Complex exon-intron marking by histone modifications is not determined solely by nucleosome distribution.

Directory of Open Access Journals (Sweden)

Pawandeep Dhami

2010-08-01

Full Text Available It has recently been shown that nucleosome distribution, histone modifications and RNA polymerase II (Pol II occupancy show preferential association with exons ("exon-intron marking", linking chromatin structure and function to co-transcriptional splicing in a variety of eukaryotes. Previous ChIP-sequencing studies suggested that these marking patterns reflect the nucleosomal landscape. By analyzing ChIP-chip datasets across the human genome in three cell types, we have found that this marking system is far more complex than previously observed. We show here that a range of histone modifications and Pol II are preferentially associated with exons. However, there is noticeable cell-type specificity in the degree of exon marking by histone modifications and, surprisingly, this is also reflected in some histone modifications patterns showing biases towards introns. Exon-intron marking is laid down in the absence of transcription on silent genes, with some marking biases changing or becoming reversed for genes expressed at different levels. Furthermore, the relationship of this marking system with splicing is not simple, with only some histone modifications reflecting exon usage/inclusion, while others mirror patterns of exon exclusion. By examining nucleosomal distributions in all three cell types, we demonstrate that these histone modification patterns cannot solely be accounted for by differences in nucleosome levels between exons and introns. In addition, because of inherent differences between ChIP-chip array and ChIP-sequencing approaches, these platforms report different nucleosome distribution patterns across the human genome. Our findings confound existing views and point to active cellular mechanisms which dynamically regulate histone modification levels and account for exon-intron marking. We believe that these histone modification patterns provide links between chromatin accessibility, Pol II movement and co-transcriptional splicing.

High contrast laser marking of alumina

Science.gov (United States)

Penide, J.; Quintero, F.; Riveiro, A.; Fernández, A.; del Val, J.; Comesaña, R.; Lusquiños, F.; Pou, J.

2015-05-01

Alumina serves as raw material for a broad range of advanced ceramic products. These elements should usually be identified by some characters or symbols printed directly on them. In this sense, laser marking is an efficient, reliable and widely implemented process in industry. However, laser marking of alumina still leads to poor results since the process is not able to produce a dark mark, yielding bad contrast. In this paper, we present an experimental study on the process of marking alumina by three different lasers working in two wavelengths: 1064 nm (Near-infrared) and 532 nm (visible, green radiation). A colorimetric analysis has been carried out in order to compare the resulting marks and its contrast. The most suitable laser operating conditions were also defined and are reported here. Moreover, the physical process of marking by NIR lasers is discussed in detail. Field Emission Scanning Electron Microscopy, High Resolution Transmission Electron Microscopy and X-ray Photoelectron Spectroscopy were also employed to analyze the results. Finally, we propose an explanation for the differences of the coloration induced under different atmospheres and laser parameters. We concluded that the atmosphere is the key parameter, being the inert one the best choice to produce the darkest marks.

27 CFR 28.123 - Export marks.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.123..., or Transportation to a Manufacturing Bonded Warehouse § 28.123 Export marks. (a) General. In addition... filled under the provisions of part 24 of this chapter, the proprietor shall mark the word “Export” on...

Experimental investigations on fiber laser color marking of steels

Energy Technology Data Exchange (ETDEWEB)

Amara, E.H., E-mail: amara@cdta.dz; Haïd, F.; Noukaz, A.

2015-10-01

Highlights: • We develop an experimental approach with the aim to bring a contribution to the comprehension of the occurring phenomena during laser color marking of steels. • We have used a home-made marking device composed of a pulsed fiber laser and galvanometric mirrors. • Both commercial and elaborated in laboratory steels have been used as samples. • The experiments have been performed for different laser beam operating parameters, under normal atmospheric conditions. • The treated samples were analyzed either by optical and scanning electronic microscopy, as well as by energy dispersion spectroscopy. - Abstract: We develop an experimental approach with the aim to bring a contribution to the comprehension of the occurring phenomena during laser color marking of steels. A home-made marking device using a pulsed fiber laser has been used to treat steel samples under different laser beam operating parameters, for different compositions of the processed steel, and at normal atmospheric conditions. The treated samples were analyzed either by optical and scanning electronic microscopy, as well as by energy dispersion spectroscopy. The results show the influence of the operating parameters on the obtained colors.

Experimental investigations on fiber laser color marking of steels

International Nuclear Information System (INIS)

Amara, E.H.; Haïd, F.; Noukaz, A.

2015-01-01

Highlights: • We develop an experimental approach with the aim to bring a contribution to the comprehension of the occurring phenomena during laser color marking of steels. • We have used a home-made marking device composed of a pulsed fiber laser and galvanometric mirrors. • Both commercial and elaborated in laboratory steels have been used as samples. • The experiments have been performed for different laser beam operating parameters, under normal atmospheric conditions. • The treated samples were analyzed either by optical and scanning electronic microscopy, as well as by energy dispersion spectroscopy. - Abstract: We develop an experimental approach with the aim to bring a contribution to the comprehension of the occurring phenomena during laser color marking of steels. A home-made marking device using a pulsed fiber laser has been used to treat steel samples under different laser beam operating parameters, for different compositions of the processed steel, and at normal atmospheric conditions. The treated samples were analyzed either by optical and scanning electronic microscopy, as well as by energy dispersion spectroscopy. The results show the influence of the operating parameters on the obtained colors

27 CFR 28.223 - Export marks.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.223... Export marks. In addition to the marks and brands required to be placed on kegs, barrels, cases, crates... “Export” on each container or case before removal for export, for use on vessels or aircraft, or for...

Handheld single photon emission computed tomography (handheld SPECT) navigated video-assisted thoracoscopic surgery of computer tomography-guided radioactively marked pulmonary lesions.

Science.gov (United States)

Müller, Joachim; Putora, Paul Martin; Schneider, Tino; Zeisel, Christoph; Brutsche, Martin; Baty, Florent; Markus, Alexander; Kick, Jochen

2016-09-01

Radioactive marking can be a valuable extension to minimally invasive surgery. The technique has been clinically applied in procedures involving sentinel lymph nodes, parathyroidectomy as well as interventions in thoracic surgery. Improvements in equipment and techniques allow one to improve the limits. Pulmonary nodules are frequently surgically removed for diagnostic or therapeutic reasons; here video-assisted thoracoscopic surgery (VATS) is the preferred technique. VATS might be impossible with nodules that are small or located deep in the lung. In this study, we examined the clinical application and safety of employing the newly developed handheld single photon emission tomography (handheld SPECT) device in combination with CT-guided radioactive marking of pulmonary nodules. In this pilot study, 10 subjects requiring surgical resection of a pulmonary nodule were included. The technique involved CT-guided marking of the target nodule with a 20-G needle, with subsequent injection of 25-30 MBq (effective: 7-14 MBq) Tc-99m MAA (Macro Albumin Aggregate). Quality control was made with conventional SPECT-CT to confirm the correct localization and exclude possible complications related to the puncture procedure. VATS was subsequently carried out using the handheld SPECT to localize the radioactivity intraoperatively and therefore the target nodule. A 3D virtual image was superimposed on the intraoperative visual image for surgical guidance. In 9 of the 10 subjects, the radioactive application was successfully placed directly in or in the immediate vicinity of the target nodule. The average size of the involved nodules was 9 mm (range 4-15). All successfully marked nodules were subsequently completely excised (R0) using VATS. The procedure was well tolerated. An asymptomatic clinically insignificant pneumothorax occurred in 5 subjects. Two subjects were found to have non-significant discrete haemorrhage in the infiltration canal of the needle. In a single subject, the

Definition of distance for nonlinear time series analysis of marked point process data

Energy Technology Data Exchange (ETDEWEB)

Iwayama, Koji, E-mail: koji@sat.t.u-tokyo.ac.jp [Research Institute for Food and Agriculture, Ryukoku Univeristy, 1-5 Yokotani, Seta Oe-cho, Otsu-Shi, Shiga 520-2194 (Japan); Hirata, Yoshito; Aihara, Kazuyuki [Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505 (Japan)

2017-01-30

Marked point process data are time series of discrete events accompanied with some values, such as economic trades, earthquakes, and lightnings. A distance for marked point process data allows us to apply nonlinear time series analysis to such data. We propose a distance for marked point process data which can be calculated much faster than the existing distance when the number of marks is small. Furthermore, under some assumptions, the Kullback–Leibler divergences between posterior distributions for neighbors defined by this distance are small. We performed some numerical simulations showing that analysis based on the proposed distance is effective. - Highlights: • A new distance for marked point process data is proposed. • The distance can be computed fast enough for a small number of marks. • The method to optimize parameter values of the distance is also proposed. • Numerical simulations indicate that the analysis based on the distance is effective.

46 CFR 78.50-5 - Hull markings.

Science.gov (United States)

2010-10-01

... 46 Shipping 3 2010-10-01 2010-10-01 false Hull markings. 78.50-5 Section 78.50-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PASSENGER VESSELS OPERATIONS Markings on Vessels § 78.50-5 Hull markings. Vessels shall be marked as required by parts 67 and 69 of this chapter. [CGD 72...

46 CFR 196.40-5 - Hull markings.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Hull markings. 196.40-5 Section 196.40-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS OPERATIONS Markings on Vessels § 196.40-5 Hull markings. Vessels shall be marked as required by parts 67 and 69 of this chapter...

46 CFR 97.40-5 - Hull markings.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Hull markings. 97.40-5 Section 97.40-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CARGO AND MISCELLANEOUS VESSELS OPERATIONS Markings on Vessels § 97.40-5 Hull markings. Vessels shall be marked as required by parts 67 and 69 of this...

Identifying the null subject: evidence from event-related brain potentials.

Science.gov (United States)

Demestre, J; Meltzer, S; García-Albea, J E; Vigil, A

1999-05-01

Event-related brain potentials (ERPs) were recorded during spoken language comprehension to study the on-line effects of gender agreement violations in controlled infinitival complements. Spanish sentences were constructed in which the complement clause contained a predicate adjective marked for syntactic gender. By manipulating the gender of the antecedent (i.e., the controller) of the implicit subject while holding constant the gender of the adjective, pairs of grammatical and ungrammatical sentences were created. The detection of such a gender agreement violation would indicate that the parser had established the coreference relation between the null subject and its antecedent. The results showed a complex biphasic ERP (i.e., an early negativity with prominence at anterior and central sites, followed by a centroparietal positivity) in the violating condition as compared to the non-violating conditions. The brain reacts to NP-adjective gender agreement violations within a few hundred milliseconds of their occurrence. The data imply that the parser has properly coindexed the null subject of an infinitive clause with its antecedent.

Monopoly, Pareto and Ramsey mark-ups

OpenAIRE

Ten Raa, T.

2009-01-01

Monopoly prices are too high. It is a price level problem, in the sense that the relative mark-ups have Ramsey optimal proportions, at least for independent constant elasticity demands. I show that this feature of monopoly prices breaks down the moment one demand is replaced by the textbook linear demand or, even within the constant elasticity framework, dependence is introduced. The analysis provides a single Generalized Inverse Elasticity Rule for the problems of monopoly, Pareto and Ramsey.

Structural Packaging in the Input to Language Learning: Contributions of Prosodic and Morphological Marking of Phrases to the Acquisition of Language.

Science.gov (United States)

Morgan, James L.; And Others

1987-01-01

The role of cues in language acquisition was examined in three experiments. When the cue marked the phrase structure of sentences, adult subjects successfully learned syntax. When input was identical but lacked that cue, subjects failed to learn significant portions of syntax. (Author/GDC)

Determination of the characteristics of a Schottky barrier formed by latent finger mark corrosion of brass

International Nuclear Information System (INIS)

Bond, J W

2009-01-01

The ideality factor (η) and barrier height (φ B ) for a metal-copper(I) oxide rectifying contact formed by the latent finger mark corrosion of α phase brass have been determined from forward bias I/V characteristics in the range 0.4 V ≤ V ≤ 0.55 V. Rectifying contacts formed from the finger mark deposits of different people gave η = 1.5-1.6 ± 0.1 and φ B = 0.49-0.52 ± 0.04 V. A Mott-Schottky plot of capacitance-voltage measurements in reverse bias gave the built in potential ψ bi = 0.4 ± 0.1 V, the gradient of the plot confirming the conductivity of the finger mark corrosion as p type. X-ray photoelectron spectroscopy spectra of the corrosion showed that Cu(I), Cu(II) and Zn(II) can co-exist on the surface, the Cu(I) : Cu(II) and Zn : Cu ratios determining whether a rectifying contact is formed. Initial findings suggest that when the concentration of Cu(I) dominates the Cu(I) : Cu(II) ratio (approximately 6 : 1), or when Cu(II) is absent, a rectifying contact can be formed subject to the Zn : Cu ratio being approximately 1 : 3. As the surface concentration of zinc increases, the rectifying contact is degraded until the concentration of zinc approaches that of copper when no evidence of a Schottky barrier is observed and the contact appears ohmic.

Mark II magnetic detector for SPEAR

International Nuclear Information System (INIS)

Larsen, R.R.

1975-01-01

The Mark II Detector, presently in the design stage, is a SLAC/LBL detector project to replace the Mark I now in operation at SPEAR. While similar in concept to the Mark I it will have improved momentum resolution, shower detection, solid angle coverage for both triggering and tracking and a magnet design providing easier access to those particles transmitted through the aluminum coil

Mark Napier / Mark Napier ; interv. Tilman Baumgärtel

Index Scriptorium Estoniae

Napier, Mark

2006-01-01

Ameerika kunstnikust Mark Napierist (sünd. 1961) ja tema loomingust, 2001. a. tehtud meiliintervjuu kunstnikuga. Võrguteosest "The Digital Landfill" (1998), koos Andy Deckiga loodud tööst "GrafficJam" (1999), töödest "Shredder" (1998), "Feed", "Riot", "P-Soup" (2000), võrgukunstist ja muust

A Novel Marking Reader for Progressive Addition Lenses Based on Gabor Holography.

Science.gov (United States)

Perucho, Beatriz; Picazo-Bueno, José Angel; Micó, Vicente

2016-05-01

Progressive addition lenses (PALs) are marked with permanent engraved marks (PEMs) at standardized locations. Permanent engraved marks are very useful through the manufacturing and mounting processes, act as locator marks to re-ink the removable marks, and contain useful information about the PAL. However, PEMs are often faint and weak, obscured by scratches, partially occluded, and difficult to recognize on tinted lenses or with antireflection or scratch-resistant coatings. The aim of this article is to present a new generation of portable marking reader based on an extremely simplified concept for visualization and identification of PEMs in PALs. Permanent engraved marks on different PALs are visualized using classical Gabor holography as underlying principle. Gabor holography allows phase sample visualization with adjustable magnification and can be implemented in either classical or digital versions. Here, visual Gabor holography is used to provide a magnified defocused image of the PEMs onto a translucent visualization screen where the PEM is clearly identified. Different types of PALs (conventional, personalized, old and scratched, sunglasses, etc.) have been tested to visualize PEMs with the proposed marking reader. The PEMs are visible in every case, and variable magnification factor can be achieved simply moving up and down the PAL in the instrument. In addition, a second illumination wavelength is also tested, showing the applicability of this novel marking reader for different illuminations. A new concept of marking reader ophthalmic instrument has been presented and validated in the laboratory. The configuration involves only a commercial-grade laser diode and a visualization screen for PEM identification. The instrument is portable, economic, and easy to use, and it can be used for identifying patient's current PAL model and for marking removable PALs again or finding test points regardless of the age of the PAL, its scratches, tints, or coatings.

Radioactive marking of proteins in cultured mouse embryos

International Nuclear Information System (INIS)

Nowak, J.

1984-01-01

The purpose of this work was to build an in vitro test system, with which on the one hand postimplantation embryos of the mouse could be cultured without morphological of physiological damage and on the other hand their protein could be as highly marked as possible. With this radioactively marked proteins were to be won, which are optimally suited for a high separation by two-dimensional electrophoresis. In addition incubation and preparation methods were found for the ages of day 10, 11 and 12 of the embryonic development. With the use of 3 H-marked amino acids in the culture medium it was determined that embryos without embryonic membranes, so-called N-embryos, built in more radioactivity into their proteins than the embryos with embryonic membranes, the so-called DAO-embryos or the DO-embryos. On the contrary, the embryos with intact blood circulation (DO-embryos) showed an even distribution of radioactive marker in their bodies. Since an even distribution of the marker in the embryo is a necessary prerequisite for a representative presentation of the proteins by 2DE, the DO-preparation was considered the best suited method. In order to increase the amount of radioactivity incorporated into the proteins of the DO-embryos, the concentration of the used isotope or the incubation length could be increased. A combination of both proved to be the best method. A 14 C-marked amino acid mixture of 20 μCi/corresponds to 20 μl instead of the usual 150 μCi 3 H-marked amino acids in a culture medium proved to be equally suitable. Notable changes which would have indicated a damaging affect of the used radioactivity or the in vitro culturing were not observed. The achieved methodical conditions were used for the presentation of the embryo proteins by two-dimensional electrophoresis and fluorography. (orig./MG) [de

Responses of female rock lizards to multiple scent marks of males: effects of male age, male density and scent over-marking.

Science.gov (United States)

Martín, José; López, Pilar

2013-03-01

Scent-marked substrates may inform conspecifics on the characteristics of territorial males. Scent-marks of male Carpetan rock lizards (Iberolacerta cyreni) affect space use of females, which by selecting an area may increase the probability of mating with the male that has scent-marked that area. However, males do not hold exclusive territories, and scent-marks of different individual males are often together. This may provide complex information from multiple sources on the social structure. Here, we examined female preference in response to scent marks of various males and combinations in a laboratory experiment. Females preferred areas scent-marked by territorial old males against those scent-marked by young satellite-sneaker males. This reflected the known preference of females for mating with old males. In a second experiment, females preferred areas scent-marked by two males to areas of similar size marked by a single male. This may increase the probability of obtaining multiple copulations with different males, which may favour sperm competition and cryptic female choice, or may be a way to avoid infertile males. Finally, when we experimentally over-marked the scent-marks of an old male with scent-marks of a young male, females did not avoid, nor prefer, the over-marked area, suggesting that the quality of the old male may override the presence of a satellite male. We suggest that, irrespective of the causes underlying why a female selects a scent-marked area, this strategy may affect her reproductive success, which may have the same evolutionary consequences that "direct" mate choice decisions of other animals. Copyright © 2013 Elsevier B.V. All rights reserved.

Percentage Retail Mark-Ups

OpenAIRE

Thomas von Ungern-Sternberg

1999-01-01

A common assumption in the literature on the double marginalization problem is that the retailer can set his mark-up only in the second stage of the game after the producer has moved. To the extent that the sequence of moves is designed to reflect the relative bargaining power of the two parties it is just as plausible to let the retailer move first. Furthermore, retailers frequently calculate their selling prices by adding a percentage mark-up to their wholesale prices. This allows a retaile...

Laser marking method and device

International Nuclear Information System (INIS)

Okazaki, Yuki; Aoki, Nobutada; Mukai, Narihiko; Sano, Yuji; Yamamoto, Seiji.

1997-01-01

An object is disposed in laser beam permeating liquid or gaseous medium. Laser beams such as CW laser or pulse laser oscillated from a laser device are emitted to the object to apply laser markings with less degradation of identification and excellent corrosion resistance on the surface of the object simply and easily. Upon applying the laser markings, a liquid or gas as a laser beam permeating medium is blown onto the surface of the object, or the liquid or gas in the vicinity of the object is sucked, the laser beam-irradiated portion on the surface can be cooled positively. Accordingly, the laser marking can be formed on the surface of the object with less heat affection to the object. In addition, if the content of a nitrogen gas in the laser beam permeating liquid medium is reduced by degassing to lower than a predetermined value, or the laser beam permeating gaseous medium is formed by an inert gas, a laser marking having high corrosion resistance and reliability can be formed on the surface of the objective member. (N.H.)

Trail marking by caterpillars of the silverspot butterfly Dione juno huascuma.

Science.gov (United States)

Pescador-Rubio, Alfonso; Stanford-Camargo, Sergio G; Páez-Gerardo, Luis E; Ramírez-Reyes, Alberto J; Ibarra-Jiménez, René A; Fitzgerald, Terrence D

2011-01-01

A pheromone is implicated in the trail marking behavior of caterpillars of the nymphalid silverspot butterfly, Dione juno huascuma (Reakirt) (Lepidoptera: Heliconiinae) that feed gregariously on Passiflora (Malpighiales: Passifloraceae) vines in Mexico. Although they mark pathways leading from one feeding site to another with silk, this study shows that the silk was neither adequate nor necessary to elicit trail following behavior. Caterpillars marked trails with a long-lived pheromone that was deposited when they brushed the ventral surfaces of the tips of their abdomens along branch pathways. The caterpillars distinguished between pathways deposited by different numbers of siblings and between trails of different ages. Caterpillars also preferentially followed the trails of conspecifics over those of another nymphalid, Nymphalis antiopa L., the mourning cloak butterfly.

Mark 4A project training evaluation

Science.gov (United States)

Stephenson, S. N.

1985-01-01

A participant evaluation of a Deep Space Network (DSN) is described. The Mark IVA project is an implementation to upgrade the tracking and data acquisition systems of the dSN. Approximately six hundred DSN operations and engineering maintenance personnel were surveyed. The survey obtained a convenience sample including trained people within the population in order to learn what training had taken place and to what effect. The survey questionnaire used modifications of standard rating scales to evaluate over one hundred items in four training dimensions. The scope of the evaluation included Mark IVA vendor training, a systems familiarization training seminar, engineering training classes, a on-the-job training. Measures of central tendency were made from participant rating responses. Chi square tests of statistical significance were performed on the data. The evaluation results indicated that the effects of different Mark INA training methods could be measured according to certain ratings of technical training effectiveness, and that the Mark IVA technical training has exhibited positive effects on the abilities of DSN personnel to operate and maintain new Mark IVA equipment systems.

Mark 4A project training evaluation

Science.gov (United States)

Stephenson, S. N.

1985-11-01

A participant evaluation of a Deep Space Network (DSN) is described. The Mark IVA project is an implementation to upgrade the tracking and data acquisition systems of the dSN. Approximately six hundred DSN operations and engineering maintenance personnel were surveyed. The survey obtained a convenience sample including trained people within the population in order to learn what training had taken place and to what effect. The survey questionnaire used modifications of standard rating scales to evaluate over one hundred items in four training dimensions. The scope of the evaluation included Mark IVA vendor training, a systems familiarization training seminar, engineering training classes, a on-the-job training. Measures of central tendency were made from participant rating responses. Chi square tests of statistical significance were performed on the data. The evaluation results indicated that the effects of different Mark INA training methods could be measured according to certain ratings of technical training effectiveness, and that the Mark IVA technical training has exhibited positive effects on the abilities of DSN personnel to operate and maintain new Mark IVA equipment systems.

Automatic Extraction of Road Markings from Mobile Laser-Point Cloud Using Intensity Data

Science.gov (United States)

Yao, L.; Chen, Q.; Qin, C.; Wu, H.; Zhang, S.

2018-04-01

With the development of intelligent transportation, road's high precision information data has been widely applied in many fields. This paper proposes a concise and practical way to extract road marking information from point cloud data collected by mobile mapping system (MMS). The method contains three steps. Firstly, road surface is segmented through edge detection from scan lines. Then the intensity image is generated by inverse distance weighted (IDW) interpolation and the road marking is extracted by using adaptive threshold segmentation based on integral image without intensity calibration. Moreover, the noise is reduced by removing a small number of plaque pixels from binary image. Finally, point cloud mapped from binary image is clustered into marking objects according to Euclidean distance, and using a series of algorithms including template matching and feature attribute filtering for the classification of linear markings, arrow markings and guidelines. Through processing the point cloud data collected by RIEGL VUX-1 in case area, the results show that the F-score of marking extraction is 0.83, and the average classification rate is 0.9.

Cavernous hemangioma presenting marked hyperostosis

International Nuclear Information System (INIS)

Kobata, Hitoshi; Miyake, Hiroji; Kitamura, Junji; Kajikawa, Hiroshi; Ohta, Tomio

1988-01-01

The authors report here a case of hemangioma of the left parietal bone which presented headache and papilledema. This patient is a 37-year-old female who had, prior to admission, complained of increasing headache for one year and blurred vision for three months. She had no history of head injury. Local physical examinations revealed a slight bulging in her left parietal region which was insensitive to palpation and not adherent to the overlying scalp. Neurological examinations revealed bilateral papilledema and an incongruous bitemporal upper quadrant defect in the visual field. All the other neurological and laboratory data were normal. A plain skull roentogenogram showed a 9 x 9 cm osteolytic and characteristic honeycomb lesion in the parietal region. Systemic bone survey revealed a similar lesion in the right tibia which was not histologically examined. A marked accumulation of isotopes was detected on the bone scintigrams at both lesions. Selective external carotid angiograms demonstrated a tumor stain fed by the superficial temporal, occipital, and middle meningial arteries. CT scans of the brain and skull clearly showed a local thickening of and structural changes in the skull bone and also a mass effect on the brain and lateral ventricle. The lesioned bone was removed en bloc and replaced by an artificial bone. It was highly vascular, but not adherent to the overlying dura. The post-operative course was uneventful, and the headache and papilledema disappeared. Hemangioma of the skull presenting marked hyperostosis, as reported above, seems to be rare. In addition, in this case, skeletal angioma without any clinical manifestation was detected. Clinical and radiological pictures of the hemangioma of the skull and other bones were briefly discussed. (author)

Mark 4A DSN receiver-exciter and transmitter subsystems

Science.gov (United States)

Wick, M. R.

1986-01-01

The present configuration of the Mark 4A DSN Receiver-Exciter and Transmitter Subsystems is described. Functional requirements and key characteristics are given to show the differences in the capabilities required by the Networks Consolidation task for combined High Earth Orbiter and Deep Space Network tracking support.

Cooperative Shark Mark Recapture Database (MRDBS)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The Shark Mark Recapture Database is a Cooperative Research Program database system used to keep multispecies mark-recapture information in a common format for...

MarkIT büroo = Offices of MarkIT

Index Scriptorium Estoniae

2010-01-01

Tallinnas Pärnu mnt. 102C asuvas büroohoones paikneva MarkIT büroo sisekujundusest. Sisearhitektid Kard Männil (SAB Miu Miu Miu) ja Loreida Hein (Studio La), nende tähtsamate tööde loetelu. Valge büroomööbel on sisearhitektide projekteeritud. Graafika on sisearhitektid ise joonistanud

User’s guide for MapMark4GUI—A graphical user interface for the MapMark4 R package

Science.gov (United States)

Shapiro, Jason

2018-05-29

MapMark4GUI is an R graphical user interface (GUI) developed by the U.S. Geological Survey to support user implementation of the MapMark4 R statistical software package. MapMark4 was developed by the U.S. Geological Survey to implement probability calculations for simulating undiscovered mineral resources in quantitative mineral resource assessments. The GUI provides an easy-to-use tool to input data, run simulations, and format output results for the MapMark4 package. The GUI is written and accessed in the R statistical programming language. This user’s guide includes instructions on installing and running MapMark4GUI and descriptions of the statistical output processes, output files, and test data files.

Minimal Marking: A Success Story

Directory of Open Access Journals (Sweden)

Anne McNeilly

2014-11-01

Full Text Available The minimal-marking project conducted in Ryerson’s School of Journalism throughout 2012 and early 2013 resulted in significantly higher grammar scores in two first-year classes of minimally marked university students when compared to two traditionally marked classes. The “minimal-marking” concept (Haswell, 1983, which requires dramatically more student engagement, resulted in more successful learning outcomes for surface-level knowledge acquisition than the more traditional approach of “teacher-corrects-all.” Results suggest it would be effective, not just for grammar, punctuation, and word usage, the objective here, but for any material that requires rote-memory learning, such as the Associated Press or Canadian Press style rules used by news publications across North America.

Male and female meadow voles Microtus pennsylvanicus respond differently to scent marks from the top- middle-, and bottom-scent donors of an over-mark

Directory of Open Access Journals (Sweden)

Michael H. FERKIN, Nicholas J. HOBBS, Benjamin D. FERKIN, Adam C.FERKIN, Daniel A. FERKIN

2011-08-01

Full Text Available Previous studies have shown that individuals responded preferentially to the mark of the top-scent donor relative to that of the bottom-scent donor of an over-mark. However, terrestrial mammals are likely to encounter over-marks consisting of the scent marks of more than two same-sex conspecifics in the intersections of runways, near the nests of sexually receptive female conspecifics, and inside and along the borders of the territories of conspecifics. We determined how meadow voles, Microtus pennsylvanicus, respond to the marks of the top-, middle-, and bottom-scent donors of an over-mark. We tested the hypothesis that voles exposed to an over-mark will respond preferentially to the scent marks that were deposited more recently, the scent marks that were on top or near the top of the over-mark, compared to the scent marks that were deposited earlier or near the bottom of the over-mark. Voles spent more time investigating the mark of the top-scent donor than that of the either the middle- or bottom-scent donor. However, males but not female voles spent more time investigating the middle-scent mark than the bottom-scent mark. We also tested the hypothesis that voles evaluate and respond to over-marks differently from single scent marks. Voles spent more time investigating the marks of the top-, middle-, and bottom-scent donors compared to scent marks that were not part of the over-mark. Voles can distinguish among the overlapping scent marks of three scent donors and sex differences exist in the values they appear to attach to each of these scent marks [Current Zoology 57 (4: 441–448, 2011].

Radio Show on Books and Libraries as a Means of Promoting the Public Library: Marking the 200th Edition of the Show Tvoja,

Directory of Open Access Journals (Sweden)

Peter Pavletič

2014-04-01

Full Text Available ABSTRACTSince 2004, the Ciril Kosmač Library of Tolmin has been continuously preparing a radio show on books and libraries on the local radio station Alpski val. The show has been used as an advertising platform or as a means of primary library promotion. The radio show is regarded as one of the tools of what is termed market communication, and it is intended to provide broad public information on the services of a public library, to promote the library’s activities and holdings and to foster a reading culture. The aim of the show is to stimulate the potential user interest in visiting and using the services of a public library, to expand the circle of users and consequently raise the number of visits and library loans. The title of the show, its audio image, target audience, metapromotion and substantive concept are all key to planning the radio show on books and libraries. The radio show is an example of an effective tool that helps to establish the library’s ties with the local community. This example of best practices shows that it is worth pursuing this activity in Slovenia’s public libraries and highlighting it on their websites.

Evaluation of copper for divider subassembly in MCO Mark IA and Mark IV scrap fuel baskets

International Nuclear Information System (INIS)

Graves, C.E.

1997-01-01

The K Basin Spent Nuclear Fuel (SNF) Project Multi-Canister Overpack (MCO) subprojection eludes the design and fabrication of a canister that will be used to confine, contain, and maintain fuel in a critically safe array to enable its removal from the K Basins, vacuum drying, transport, staging, hot conditioning, and interim storage (Goldinann 1997). Each MCO consists of a shell, shield plug, fuel baskets (Mark IA or Mark IV), and other incidental equipment. The Mark IA intact and scrap fuel baskets are a safety class item for criticality control and components necessary for criticality control will be constructed from 304L stainless steel. It is proposed that a copper divider subassembly be used in both Mark IA and Mark IV scrap baskets to increase the safety basis margin during cold vacuum drying. The use of copper would increase the heat conducted away from hot areas in the baskets out to the wall of the MCO by both radiative and conductive heat transfer means. Thus copper subassembly will likely be a safety significant component of the scrap fuel baskets. This report examines the structural, cost and corrosion consequences associated with using a copper subassembly in the stainless steel MCO scrap fuel baskets

Utilization of Slovenian TRIGA Mark II reactor

International Nuclear Information System (INIS)

Snoj, L.; Smodis, B.

2010-01-01

TRIGA Mark II research reactor at the Jozef Stefan Institute [JSI] is extensively used for various applications, such as: irradiation of various samples, training and education, verification and validation of nuclear data and computer codes, testing and development of experimental equipment used for core physics tests at a nuclear power plant. The paper briefly describes the aforementioned activities and shows that even such small reactors are still indispensable in nuclear science and technology. (author)

An 11-digit identification system for individual Nile crocodiles using natural markings

Directory of Open Access Journals (Sweden)

Hindrik Bouwman

2016-05-01

Full Text Available Research and conservation of wild crocodiles and husbandry of captive crocodiles requires the reliable identification of individuals. We present a method using the individual colour markings on the first 10 single-crest scutes on the tails of Nile crocodiles (Crocodylus niloticus. The scutes are scored by number for colour, with a prefix for left or right providing a binary 11-digit identification number (identification numbers [IDs]; e.g. 12232232242 and 22333233232 per crocodile. A survey of 359 captive Nile crocodiles showed no duplication. However, 42% had asymmetrical scute markings requiring a binary approach. There does not seem to be a change in patterns with age, except that the number of missing scutes increased. A small trial showed that this method can be applied in the field, although more work is needed to determine observer bias and establish parameters for observability in the field. It is unlikely that both left and right IDs would be obtainable for each individual, but other distinctive markings such as scute shape and damage can be used to register the two IDs to one individual. Having two independent IDs for each crocodile provides the possibility of two independent population estimates for equal effort without having to link left and right IDs to individuals. Our proposed method would be useful in conservation, individual tracking and husbandry. Conservation implications: A non-invasive marking and recapture method for Nile crocodile is presented whereby the first 10 single-crest scutes are scored for colour, allowing conservation practitioners to count and monitor crocodile populations and individuals. This method provides two equal-effort estimations of population size, as left and right hand sides are scored independently. Keywords: Crocodylus niloticus; identification; mark - recapture; mark - resight

Negative Marking and the Student Physician–-A Descriptive Study of Nigerian Medical Schools

Directory of Open Access Journals (Sweden)

Ikenna Kingsley Ndu

2016-01-01

Full Text Available Background There is considerable debate about the two most commonly used scoring methods, namely, the formula scoring (popularly referred to as negative marking method in our environment and number right scoring methods. Although the negative marking scoring system attempts to discourage students from guessing in order to increase test reliability and validity, there is the view that it is an excessive and unfair penalty that also increases anxiety. Feedback from students is part of the education process; thus, this study assessed the perception of medical students about negative marking method for multiple choice question (MCQ examination formats and also the effect of gender and risk-taking behavior on scores obtained with this assessment method. Methods This was a prospective multicenter survey carried out among fifth year medical students in Enugu State University and the University of Nigeria. A structured questionnaire was administered to 175 medical students from the two schools, while a class test was administered to medical students from Enugu State University. Qualitative statistical methods including frequencies, percentages, and chi square were used to analyze categorical variables. Quantitative statistics using analysis of variance was used to analyze continuous variables. Results Inquiry into assessment format revealed that most of the respondents preferred MCQs (65.9%. One hundred and thirty students (74.3% had an unfavorable perception of negative marking. Thirty-nine students (22.3% agreed that negative marking reduces the tendency to guess and increases the validity of MCQs examination format in testing knowledge content of a subject compared to 108 (61.3% who disagreed with this assertion (χ 2 = 23.0, df = 1, P = 0.000. The median score of the students who were not graded with negative marking was significantly higher than the score of the students graded with negative marking ( P = 0.001. There was no statistically

Effect of artificial sunlight on the retention of external calcein marks on lake trout

Science.gov (United States)

Honeyfield, D.C.; Kehler, T.; Fletcher, J.W.; Mohler, J.W.

2008-01-01

When choosing a fish marking technique to address fishery related questions, it is important to consider factors that affect mark retention. Calcein, a chemical marking agent, is under investigation for potential use on fish. Two laboratory trials were conducted with calcein-marked lake trout Salvelinus namaycush to determine the effect of artificial sunlight on calcein mark intensity. In trial 1, fish exposed to 18,000 lx for 7 d lost 90% or more of the calcein mark intensity (relative to the colorimetric key, mg/L) on the head, body, ventral region, and pectoral fins relative to mark intensity in fish that were maintained in darkness. In trial 2, light intensity was reduced 2.5-3.0-fold. After 7 d of light exposure, calcein mark intensity on the head was reduced by 40-45% relative to mark intensity in fish that were held in darkness; by day 14, calcein mark intensity on the head was reduced by 55-60% relative to that of dark-treated fish. No further decline was observed in light-exposed fish, and head mark intensity values did not differ among days 14, 21, and 28 for this treatment group. Of the four areas evaluated, the head and pectoral fin were more easily read using a colorimetric key than the lateral or ventral regions of the fish. The concentration of calcein spotted on filter paper to devise the colorimetric key ranged from 1 to 100 mg/L. A difference of approximately 7 mg/L in apparent calcein mark intensity means for the head region could be detected using the colorimetric key. These trials showed that calcein mark intensity on lake trout declined when fish were exposed to artificial sunlight, and the use of a colorimetric key improved the objectivity of calcein mark intensity assessment.

Malignant Pleural Mesothelioma with Marked Lymphatic Involvement: A Report of Two Autopsy Cases

Directory of Open Access Journals (Sweden)

Reiko Ideguchi

2017-01-01

Full Text Available We herein report two cases of malignant pleural mesothelioma with marked lymphangiosis. The patients included a 68-year-old man and a 67-year-old man who both had a history of exposure to asbestos. Computed tomography (CT on admission showed pleural effusion with pleural thickening. In both cases, a histopathological examination of the pleura confirmed the diagnosis of epithelioid malignant mesothelioma. They received chemotherapy, but the treatment was only palliative. The chest CT assessments during admission revealed marked pleural effusion and mediastinal lymphadenopathy. CT also showed a consolidative mass with bronchovascular bundle and septal thickening in the lungs suggesting pulmonary parenchymal involvement and the lymphangitic spread of the tumor. These CT findings mimicked lung cancer with pleuritis and lymphangitic carcinomatosis. Autopsy was performed in both cases. Macroscopically, the tumor cells infiltrated the lung with the marked lymphatic spread of the tumor. Microscopy also revealed that the tumor had invaded the pulmonary parenchyma with the marked lymphatic spread of the tumor. Although this growth pattern is unusual, malignant pleural mesothelioma should be considered as the differential diagnosis, especially in patients with pleural lesions.

Glass marking with diode-pumped Nd:YLF laser; Handotai reiki Nd:YLF laser ni yoru glass marking

Energy Technology Data Exchange (ETDEWEB)

Sakai, F.; Hayashi, K. [Sumitomo Heavy Industries, Ltd., Tokyo (Japan)

1996-08-20

The compact marking system based on a beam scanning system in which the fourth harmonic (FHG: 262 nm in wavelength) of a diode-pumped Nd:YLF (Nd:LiYf4) laser is used for the source of ultraviolet light is described. The result of application to the glass marking that caused a problem due to the generation of cracks is also explained. The machining characteristics significantly vary depending on the type of glass. During actual marking, sample processing must be beforehand carried out to optimize the processing conditions after confirming that there is no problem in practical use. For marking on the glass used for liquid-crystal board, it is valid to improve the density of a dot and increase the number of shots per dot for obtaining high visibility. However, cracks may occur in the clearance of each dot because of the thermal effect. Therefore, the processing conditions must be optimized according to the glass type and crack generation state. The generation of cracks can be suppressed by setting the processing conditions to the optimum level. As a result, satisfactory marking is obtained. 8 refs., 6 figs.

Civilsamfundets ABC: M for Marked

DEFF Research Database (Denmark)

Lund, Anker Brink; Meyer, Gitte

2016-01-01

Bogstaveligt talt: Hvad er civilsamfundet? Anker Brink Lund og Gitte Meyer fra CBS Center for Civil Society Studies gennemgår civilsamfundet bogstav for bogstav. Vi er nået til M for Marked.......Bogstaveligt talt: Hvad er civilsamfundet? Anker Brink Lund og Gitte Meyer fra CBS Center for Civil Society Studies gennemgår civilsamfundet bogstav for bogstav. Vi er nået til M for Marked....

19 CFR 134.43 - Methods of marking specific articles.

Science.gov (United States)

2010-04-01

... 19 Customs Duties 1 2010-04-01 2010-04-01 false Methods of marking specific articles. 134.43...; DEPARTMENT OF THE TREASURY COUNTRY OF ORIGIN MARKING Method and Location of Marking Imported Articles § 134.43 Methods of marking specific articles. (a) Marking previously required by certain provisions of the...

Lessons learned : pavement marking warranty contract.

Science.gov (United States)

2013-12-01

In 2012, UDOT implemented a performance-based warranty on a portion of an I-15 pavement marking : project. The awarded contract requested a contractor warranty on the implemented markings for a total : duration of six years. This is the first time th...

Dihydralazine induces marked cerebral vasodilation in man

DEFF Research Database (Denmark)

Schroeder, T; Sillesen, H

1987-01-01

of dihydralazine was of the same order of magnitude as the effect of 5% CO2 inhalation. These results in normal subjects should be extrapolated to diseased persons only with extreme caution. Still, the very marked and long lasting vasodilation observed suggests that dihydralazine, from a theoretical point of view.......v. xenon-133 technique in seven young, normotensive volunteers before and 15, 60 and 180 min after 6.25 mg i.v. dihydralazine, corresponding approximately to 0.1 mg kg-1 body weight. For comparison the CBF reactivity to inhalation of 5% CO2 in air was investigated. Dihydralazine increased CBF throughout...... the period of study, in median 16, 27 and 23% at the three periods of measurements, respectively. The arterial blood pressure remained unchanged, whereas heart rate increased significantly. During CO2 inhalation, CBF increased on average 29%. Thus, the cerebral vasodilation exerted by a small i.v. dose...

Minnesota Local Agency Pavement Marking : Mining Existing Data

Science.gov (United States)

2017-11-01

Pavement marking is important for safety. Maximizing pavement marking performance in terms of increased retroreflectivity, within limited budget constraints, allows agencies to make better decisions toward providing more effective pavement marking pe...

Mark Twain: inocente ou pecador? = Mark Twain: innocent or sinner?

Directory of Open Access Journals (Sweden)

Heloisa Helou Doca

2009-01-01

Full Text Available A leitura cuidadosa do texto do “Tratado de Paris”, em 1900, leva Mark Twain a concluir que a intenção política norte-americana era, claramente, a de subjugação. Declara-se, abertamente, antiimperialista, nesse momento, apesar das inúmeras críticasrecebidas por antagonistas políticos que defendiam o establishment dos Estados Unidos. Após viajar para a Europa e Oriente, em 1867, como correspondente do jornal Daily Alta Califórnia, Mark Twain publica, em 1869, seu relato de viagem, The Innocents Abroad or TheNew Pilgrim’s Progress. Nosso estudo demonstra que o autor, apesar das diversas máscaras usadas em seus relatos, narra histórias, culturas e tradições, tanto da Europa quanto do Oriente, já com os olhos bem abertos pelo viés antiimperialista. Faz uso da paródia, sátira, ironia e humor para dessacralizar impérios, monarcas e a Igreja que subjugavam os mais fracos, iluminando, desde então, os estudos sobre culturas. Nosso estudo, outrossim, faz uma reflexão sobre cultura, tradição e o olhar do viajante, justificando o “olhar inocente” do narrador em seu relato.After carefully reading the Treaty of Paris in 1900, Mark Twain concluded that the goal of U.S. policy was clearly one ofsubjugation. He openly declared himself an anti-imperialist at that time, in spite of the numerous criticisms he received from political opponents who supported the United States status quo. After traveling to Europe and the East in 1867 as a correspondent for The DailyAlta California newspaper, Mark Twain published his travel report, The Innocents Abroad or The New Pilgrim’s Progress in 1869. Our study demonstrates that the author, in spite of using different guises in his reports, narrated histories, cultures and traditions – from both Europe and the East – with a viewpoint already imbued by his anti-imperialistic ideals. Twain made use of parody, satire, irony and humor within his texts in order to desecrate empires,monarchs and

Do employers prefer Mark over Mohammed?

NARCIS (Netherlands)

Iris Andriessen; Eline Nievers; Laila Faulk; Jaco Dagevos

2010-01-01

Original title: Liever Mark dan Mohammed? Does Mohammed have less chance of succeeding on the Dutch labour market than Mark, even though they both have the same qualifications and work experience? And are employers less friendly towards Sonaya than Paula? This study investigates the

Exploiting automatically generated databases of traffic signs and road markings for contextual co-occurrence analysis

Science.gov (United States)

Hazelhoff, Lykele; Creusen, Ivo M.; Woudsma, Thomas; de With, Peter H. N.

2015-11-01

Combined databases of road markings and traffic signs provide a complete and full description of the present traffic legislation and instructions. Such databases contribute to efficient signage maintenance, improve navigation, and benefit autonomous driving vehicles. A system is presented for the automated creation of such combined databases, which additionally investigates the benefit of this combination for automated contextual placement analysis. This analysis involves verification of the co-occurrence of traffic signs and road markings to retrieve a list of potentially incorrectly signaled (and thus potentially unsafe) road situations. This co-occurrence verification is specifically explored for both pedestrian crossings and yield situations. Evaluations on 420 km of road have shown that individual detection of traffic signs and road markings denoting these road situations can be performed with accuracies of 98% and 85%, respectively. Combining both approaches shows that over 95% of the pedestrian crossings and give-way situations can be identified. An exploration toward additional co-occurrence analysis of signs and markings shows that inconsistently signaled situations can successfully be extracted, such that specific safety actions can be directed toward cases lacking signs or markings, while most consistently signaled situations can be omitted from this analysis.

[Werkgartner's muzzle imprint mark--a literature study].

Science.gov (United States)

Geserick, Gunther; Vendura, Klaus; Wirth, Ingo

2009-01-01

Since Werkgartner described and correctly interpreted the muzzle imprint mark around the gunshot entrance wound in 1922, this finding has been generally accepted as a sign of a contact shot. In further studies, it could finally be clarified that the muzzle imprint mark is caused by the expansive power of the powder gases with pressure on and abrasion of the skin at the muzzle (weapon imprint). Its shape depends on the firearm, the ammunition and the anatomical conditions, but does not require a bullet. Examinations under a magnifying glass microscope and histological investigations can complete the macroscopic findings. Occasionally, the muzzle imprint mark requires a certain "drying period" in order to become clearly visible. In rare cases, muzzle imprint marks also form on textiles perforated by the projectile. Characteristically shaped muzzled imprint marks can provide clues to the type of the firearm and its position at the time of discharge.

19 CFR 11.9 - Special marking on certain articles.

Science.gov (United States)

2010-04-01

... 19 Customs Duties 1 2010-04-01 2010-04-01 false Special marking on certain articles. 11.9 Section... OF THE TREASURY PACKING AND STAMPING; MARKING Marking § 11.9 Special marking on certain articles. (a... of additional U.S. Note 4, Chapter 91. If any article so required to be marked is found not to be...

Increased delta power and discrepancies in objective and subjective sleep measurements in borderline personality disorder.

Science.gov (United States)

Philipsen, Alexandra; Feige, Bernd; Al-Shajlawi, Anam; Schmahl, Christian; Bohus, Martin; Richter, Harald; Voderholzer, Ulrich; Lieb, Klaus; Riemann, Dieter

2005-09-01

Previous studies have shown depression-like sleep abnormalities in borderline personality disorder (BPD). However, findings in BPD are not unequivocal for REM dysregulation, as well as for a decrement of slow wave sleep and sleep continuity disturbances. Earlier findings in sleep EEG abnormalities in BPD may have been confounded by concomitant depressive symptoms. Twenty unmedicated female BPD patients without current comorbid major depression and 20 sex- and age-matched control subjects entered the study. Conventional polysomnographic parameters and for the first time sleep EEG spectral power analysis was performed on two sleep laboratory nights. Subjective sleep parameters were collected by sleep questionnaires in order to assess the relationship between objective and subjective sleep measurements. BPD patients showed a tendency for shortened REM latency and significantly decreased NonREM sleep (stage 2). Spectral EEG analysis showed increased delta power in total NREM sleep as well as in REM sleep in BPD patients. Subjective ratings documented drastically impaired sleep quality in BPD patients for the two weeks before the study and during the two laboratory nights. Not-depressed BPD patients only showed tendencies for depression-like REM sleep abnormalities. Surprisingly, BPD patients displayed higher levels of delta power in the sleep EEG in NREM sleep than healthy control subjects. There was a marked discrepancy between objective and subjective sleep measurements, which indicates an altered perception of sleep in BPD. The underlying psychological and neurobiological mechanisms of these alterations are still unclear and need to be clarified in future studies including interventions on a pharmacological and cognitive-behavioral level.

Replication stress interferes with histone recycling and predeposition marking of new histones

DEFF Research Database (Denmark)

Jasencakova, Zuzana; Scharf, Annette N D; Ask, Katrine

2010-01-01

To restore chromatin on new DNA during replication, recycling of histones evicted ahead of the fork is combined with new histone deposition. The Asf1 histone chaperone, which buffers excess histones under stress, is a key player in this process. Yet how histones handled by human Asf1 are modified...... remains unclear. Here we identify marks on histones H3-H4 bound to Asf1 and changes induced upon replication stress. In S phase, distinct cytosolic and nuclear Asf1b complexes show ubiquitous H4K5K12diAc and heterogeneous H3 marks, including K9me1, K14ac, K18ac, and K56ac. Upon acute replication arrest......, the predeposition mark H3K9me1 and modifications typical of chromatin accumulate in Asf1 complexes. In parallel, ssDNA is generated at replication sites, consistent with evicted histones being trapped with Asf1. During recovery, histones stored with Asf1 are rapidly used as replication resumes. This shows...

How Prosody Marks Shifts in Footing in Classroom Discourse

Science.gov (United States)

Skidmore, David; Murakami, Kyoko

2010-01-01

Prosody refers to features of speech such as intonation, volume and pace. In this paper, we examine teacher-student dialogue in an English lesson at a secondary school in England, using Conversation Analysis notation to mark features of prosody. We also make connections with Goffman's theoretical concept of footing. We show that, within an episode…

49 CFR 178.338-18 - Marking.

Science.gov (United States)

2010-10-01

... pounds. (7) Maximum design density of lading (Max. Lading density), in pounds per gallon. (8) Material... cryogenic liquid, in hours, and the name of that cryogenic liquid (MRHT __ hrs, name of cryogenic liquid). Marked rated holding marking for additional cryogenic liquids may be displayed on or adjacent to the...

7 CFR 956.162 - Container markings.

Science.gov (United States)

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Container markings. 956.162 Section 956.162... WALLA VALLEY OF SOUTHEAST WASHINGTON AND NORTHEAST OREGON Rules and Regulations § 956.162 Container markings. Effective April 15, 1997, no handler shall ship any container of Walla Walla Sweet Onions except...

Metallographic examinations of the wear-marks on fuel pins of the KNK II/2 fuel assembly NY-308

International Nuclear Information System (INIS)

Patzer, G.

1987-12-01

On the fuel pins and pin spacers of the fuel assembly NY-308 of the second core of KNK II pronounced wear marks had been found in the area of the contact points. In order to determine the exact form of the marks, metallographic investigations were performed on two test pieces of fuel pins in the Hot Cells of the KfK Karlsruhe. It was found that the wear marks did show the already observed stratified structure. Next to the unchanged cladding area there is a peripheral zone with modified grain structure, followed by a layer of moved material and finally there is a flake-like zone of accumulated cladding material at the lower end of the wear marks. Longitudinal cuts do not show grain deformations, which could indicate axial friction forces between pin and spacer. The wear marks are rapidly dropping to their maximum depth at the ends and the depth shows a relatively uniform pattern between both. The findings are confirming the picture, that a stirring movement of the fuel pins took place, which caused adhesive wear [de

Marks on the petroleum fiscality

International Nuclear Information System (INIS)

2007-02-01

This document offers some marks on the petroleum fiscality in France: the taxes as the 'accises' and the 'TVA', the part of the taxes in the sale price at the service station, the comparison with other countries of Europe, the tax revenues and the Government budget. It provides also marks on the fuels prices formation (margins), the world petroleum markets (supply and demand) and the part of the petroleum companies on the petroleum market. (A.L.B.)

14 CFR 1203.501 - Applying derivative classification markings.

Science.gov (United States)

2010-01-01

... INFORMATION SECURITY PROGRAM Derivative Classification § 1203.501 Applying derivative classification markings. Persons who apply derivative classification markings shall: (a) Observe and respect original... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Applying derivative classification markings...

Aluminum-Oxide Temperatures on the Mark VB, VE, VR, 15, and Mark 25 Assemblies

International Nuclear Information System (INIS)

Aleman, S.E.

2001-01-01

The task was to compute the maximum aluminum-oxide and oxide-coolant temperatures of assemblies cladded in 99+ percent aluminum. The assemblies considered were the Mark VB, VE, V5, 15 and 25. These assemblies consist of nested slug columns with individual uranium slugs cladded in aluminum cans. The CREDIT code was modified to calculate the oxide film thickness and the aluminum-oxide temperature at each axial increment. This information in this report will be used to evaluate the potential for cladding corrosion of the Mark 25 assembly

The scent marking behaviour of the brown hyaena Hyaena brunnea

African Journals Online (AJOL)

1977). Here urine marking is seen to be used as a signal showing that, although there might be a food odour at a particular place, the food has been eaten. In addition to this intra-group function pasting may also serve to pass information between ...

Effect of levamisole and methisoprinol on in vitro lymphocyte reactivity in chronically irradiated subjects and patients affected by neoplasias

Energy Technology Data Exchange (ETDEWEB)

Campo, M.; Chiavaro, I.; Canfarotta, C.; Stivala, F.; Berrardini, A.

1982-01-01

The data of this experiment show that Levamisole moderately stimulates T-lymphocyte proliferation and efficiency in vitro and methisoprinol markedly does so when both drugs act in combination with PHA in subjects with severely impaired cell-mediated responsiveness, whereas they do not exert any effect on lymphocytes in normal subjects. B-lymphocyte in vitro responsiveness does not appear to be affected by the immunomodulators, except for some cases of cancer of the stomach wherein B-lymphocyte responsiveness is stimulated in vitro by Levamisole and more evidently by Methisoprinol. These data support the use of Methisoprinol or Levamisole in therapy, and further investigations regarding the mechanisms whereby they might act and the dose-effect relationship which might show to be important for the type of desired immunomodulation would appear appropriate.

Effect of levamisole and methisoprinol on in vitro lymphocyte reactivity in chronically irradiated subjects and patients affected by neoplasias

International Nuclear Information System (INIS)

Campo, M.; Chiavaro, I.; Canfarotta, C.; Stivala, F.; Berrardini, A.

1982-01-01

The data of this experiment show that Levamisole moderately stimulates T-lymphocyte proliferation and efficiency in vitro and methisoprinol markedly does so when both drugs act in combination with PHA in subjects with severely impaired cell-mediated responsiveness, whereas they do not exert any effect on lymphocytes in normal subjects. B-lymphocyte in vitro responsiveness does not appear to be affected by the immunomodulators, except for some cases of cancer of the stomach wherein B-lymphocyte responsiveness is stimulated in vitro by Levamisole and more evidently by Methisoprinol. These data support the use of Methisoprinol or Levamisole in therapy, and further investigations regarding the mechanisms whereby they might act and the dose-effect relationship which might show to be important for the type of desired immunomodulation would appear appropriate

Amphibian DNA shows marked genetic structure and tracks pleistocene climate change in northeastern Brazil.

Science.gov (United States)

Carnaval, Ana Carolina; Bates, John M

2007-12-01

The glacial refugia paradigm has been broadly applied to patterns of species dynamics and population diversification. However, recent geological studies have demonstrated striking Pleistocene climate changes in currently semiarid northeastern Brazil at time intervals much more frequent than the climatic oscillations associated with glacial and interglacial periods. These geomorphic data documented recurrent pulses of wet regimes in the past 210,000 years that correlate with climate anomalies affecting multiple continents. While analyzing DNA sequences of two mitochondrial genes (cytochrome b and NADH-dehydrogenase subunit 2) and one nuclear marker (cellular-myelocytomatosis proto-oncogene) in the forest-associated frogs Proceratophrys boiei and Ischnocnema gr. ramagii, we found evidence of biological responses consistent with these pluvial maxima events. Sampled areas included old, naturally isolated forest enclaves within the semiarid Caatinga, as well as recent man-made fragments of humid coastal Atlantic forest. Results show that mtDNA lineages in enclave populations are monophyletic or nearly so, whereas nonenclave populations are polyphyletic and more diverse. The studied taxa show evidence of demographic expansions at times that match phases of pluvial maxima inferred from geological data. Divergence times between several populations fall within comparatively drier intervals suggested by geomorphology. Mitochondrial and nuclear data show local populations to be genetically structured, with some high levels of differentiation that suggest the need of further taxonomic work.

46 CFR 108.645 - Markings on lifesaving appliances.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Markings on lifesaving appliances. 108.645 Section 108.645 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Equipment Markings and Instructions § 108.645 Markings on lifesaving appliances. (a...

25 CFR 141.16 - Price marking.

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Price marking. 141.16 Section 141.16 Indians BUREAU OF... AND ZUNI RESERVATIONS General Business Practices § 141.16 Price marking. The price of each article... visible to the customer and that affords the customer a reasonable opportunity to learn the price of the...

46 CFR 199.176 - Markings on lifesaving appliances.

Science.gov (United States)

2010-10-01

... ARRANGEMENTS LIFESAVING SYSTEMS FOR CERTAIN INSPECTED VESSELS Requirements for All Vessels § 199.176 Markings on lifesaving appliances. (a) Lifeboats and rescue boats. Each lifeboat and rescue boat must be plainly marked as follows: (1) Each side of each lifeboat and rescue boat bow must be marked in block...

Types of adaptation of the system of enterprise economic security to the impact of subjects of tax regulation

Directory of Open Access Journals (Sweden)

Pohorelov Yurii S.

2014-01-01

Full Text Available The article offers the authors’ approach to identification of types of adaptation of the system of enterprise economic security to negative influence of subjects of tax regulation. It determines composition of these subjects and, separately, regulation subjects that form fundamental grounds of the tax sphere and subjects of effective influence, which directly interact with entrepreneurial structures and realise tax regulation of their activity in practice. As regards direct adaptation of the system of enterprise economic security, the article offers to mark out its individual types with respect to the set goal, essence of changes in the system of economic security, degree of its manageability and nature of accumulated changes. Moreover, the article offers a list of catalysts and inhibitors of adaptation of the system of enterprise economic security to impact of subjects of tax regulation. It also marks out adaptation parameters of the system of enterprise economic security to the impact of subjects of tax regulation and provides their gradations.

Macrophage inflammatory protein-1α shows predictive value as a risk marker for subjects and sites vulnerable to bone loss in a longitudinal model of aggressive periodontitis.

Science.gov (United States)

Fine, Daniel H; Markowitz, Kenneth; Fairlie, Karen; Tischio-Bereski, Debbie; Ferrandiz, Javier; Godboley, Dipti; Furgang, David; Gunsolley, John; Best, Al

2014-01-01

Improved diagnostics remains a fundamental goal of biomedical research. This study was designed to assess cytokine biomarkers that could predict bone loss (BL) in localized aggressive periodontitis. 2,058 adolescents were screened. Two groups of 50 periodontally healthy adolescents were enrolled in the longitudinal study. One group had Aggregatibacter actinomycetemcomitans (Aa), the putative pathogen, while the matched cohort did not. Cytokine levels were assessed in saliva and gingival crevicular fluid (GCF). Participants were sampled, examined, and radiographed every 6 months for 2-3 years. Disease was defined as radiographic evidence of BL. Saliva and GCF was collected at each visit, frozen, and then tested retrospectively after detection of BL. Sixteen subjects with Aa developed BL. Saliva from Aa-positive and Aa-negative healthy subjects was compared to subjects who developed BL. GCF was collected from 16 subjects with BL and from another 38 subjects who remained healthy. GCF from BL sites in the 16 subjects was compared to healthy sites in these same subjects and to healthy sites in subjects who remained healthy. Results showed that cytokines in saliva associated with acute inflammation were elevated in subjects who developed BL (i.e., MIP-1α MIP-1β IL-α, IL-1β and IL-8; p<0.01). MIP-1α was elevated 13-fold, 6 months prior to BL. When MIP-1α levels were set at 40 pg/ml, 98% of healthy sites were below that level (Specificity); whereas, 93% of sites with BL were higher (Sensitivity), with comparable Predictive Values of 98%; p<0.0001; 95% C.I. = 42.5-52.7). MIP-1α consistently showed elevated levels as a biomarker for BL in both saliva and GCF, 6 months prior to BL. MIP-1α continues to demonstrate its strong candidacy as a diagnostic biomarker for both subject and site vulnerability to BL.

PREOPERATIVE ENDOSCOPIC MARKING OF UNPALPABLE COLONIC TUMORS

Directory of Open Access Journals (Sweden)

A. L. Goncharov

2013-01-01

Full Text Available The identification of small colon lesions is one of the major problems in laparoscopic colonic resection.Research objective: to develop a technique of visualization of small tumors of a colon by preoperative endoscopic marking of a tumor.Materials and methods. In one day prior to operation to the patient after bowel preparation the colonoscopy is carried out. In the planned point near tumor on antimesentery edge the submucous infiltration of marking solution (Micky Sharpz blue tattoo pigment, UK is made. The volume of entered solution of 1–3 ml. In only 5 months of use of a technique preoperative marking to 14 patients with small (the size of 1–3 cm malignant tumors of the left colon is performed.Results. The tattoo mark was well visualized by during operation at 13 of 14 patients. In all cases we recorded no complications. Time of operation with preoperative marking averaged 108 min, that is significantly less in comparison with average time of operation with an intra-operative colonoscopy – 155 min (р < 0.001.Conclusions. The first experience of preoperative endoscopic marking of non palpable small tumors of a colon is encouraging. Performance of a technique wasn't accompanied by complications and allowed to reduce significantly time of operation and to simplify conditions of performance of operation.

49 CFR 1520.13 - Marking SSI.

Science.gov (United States)

2010-10-01

... SECURITY INFORMATION § 1520.13 Marking SSI. (a) Marking of paper records. In the case of paper records... back cover, including a binder cover or folder, if the document has a front and back cover; (2) Any.... 552 and 49 CFR parts 15 and 1520. (d) Other types of records. In the case of non-paper records that...

9 CFR 316.13 - Marking of outside containers.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Marking of outside containers. 316.13... INSPECTION AND CERTIFICATION MARKING PRODUCTS AND THEIR CONTAINERS § 316.13 Marking of outside containers. (a... domestic commerce is moved from an official establishment, the outside container shall bear an official...

Microscopic saw mark analysis: an empirical approach.

Science.gov (United States)

Love, Jennifer C; Derrick, Sharon M; Wiersema, Jason M; Peters, Charles

2015-01-01

Microscopic saw mark analysis is a well published and generally accepted qualitative analytical method. However, little research has focused on identifying and mitigating potential sources of error associated with the method. The presented study proposes the use of classification trees and random forest classifiers as an optimal, statistically sound approach to mitigate the potential for error of variability and outcome error in microscopic saw mark analysis. The statistical model was applied to 58 experimental saw marks created with four types of saws. The saw marks were made in fresh human femurs obtained through anatomical gift and were analyzed using a Keyence digital microscope. The statistical approach weighed the variables based on discriminatory value and produced decision trees with an associated outcome error rate of 8.62-17.82%. © 2014 American Academy of Forensic Sciences.

Streamflow characteristics at hydrologic bench-mark stations

Science.gov (United States)

Lawrence, C.L.

1987-01-01

The Hydrologic Bench-Mark Network was established in the 1960's. Its objectives were to document the hydrologic characteristics of representative undeveloped watersheds nationwide and to provide a comparative base for studying the effects of man on the hydrologic environment. The network, which consists of 57 streamflow gaging stations and one lake-stage station in 39 States, is planned for permanent operation. This interim report describes streamflow characteristics at each bench-mark site and identifies time trends in annual streamflow that have occurred during the data-collection period. The streamflow characteristics presented for each streamflow station are (1) flood and low-flow frequencies, (2) flow duration, (3) annual mean flow, and (4) the serial correlation coefficient for annual mean discharge. In addition, Kendall's tau is computed as an indicator of time trend in annual discharges. The period of record for most stations was 13 to 17 years, although several stations had longer periods of record. The longest period was 65 years for Merced River near Yosemite, Calif. Records of flow at 6 of 57 streamflow sites in the network showed a statistically significant change in annual mean discharge over the period of record, based on computations of Kendall's tau. The values of Kendall's tau ranged from -0.533 to 0.648. An examination of climatological records showed that changes in precipitation were most likely the cause for the change in annual mean discharge.

Genotoxic effect of radio marked lymphocytes using Tc-99m complexes

International Nuclear Information System (INIS)

Pedraza L, M.; Ferro F, G.; Mendiola C, M.T.; Morales R, P.

1997-01-01

The genotoxic effect of radio marked lymphocytes was evaluated using 99m -Tc-HMPAO and 99m -Tc- gentisic acid complexes. With the results of this work it is pretended to contribute to the knowledge of genetic and structural damages that provokes the radiation in the marked lymphocytes. The d, 1-HMPAO was synthesized in laboratory with a yielding of 30 %. The radiochemical purity of the complexes was greater than 85%. Mouse lymphocytes obtained of sanguineous volumes 2 ml were used. The radio marked efficiency of cells was 19.6 ± 6.4% and 25.6 ± 5.8% for 99m Tc-HMPAO and 99m Tc gentisic acid respectively. The genotoxic effect was evaluated using the technique of Unicellular Electrophoresis in Micro gel (Comet assay). The results showed that both 99m Tc complexes produce genotoxicity due to their capacity to penetrate cells, therefore the Auger and M internal conversion electrons place all their energy obtaining doses of Gray order. (Author)

Diffraction-based overlay measurement on dedicated mark using rigorous modeling method

Science.gov (United States)

Lu, Hailiang; Wang, Fan; Zhang, Qingyun; Chen, Yonghui; Zhou, Chang

2012-03-01

Diffraction Based Overlay (DBO) is widely evaluated by numerous authors, results show DBO can provide better performance than Imaging Based Overlay (IBO). However, DBO has its own problems. As well known, Modeling based DBO (mDBO) faces challenges of low measurement sensitivity and crosstalk between various structure parameters, which may result in poor accuracy and precision. Meanwhile, main obstacle encountered by empirical DBO (eDBO) is that a few pads must be employed to gain sufficient information on overlay-induced diffraction signature variations, which consumes more wafer space and costs more measuring time. Also, eDBO may suffer from mark profile asymmetry caused by processes. In this paper, we propose an alternative DBO technology that employs a dedicated overlay mark and takes a rigorous modeling approach. This technology needs only two or three pads for each direction, which is economic and time saving. While overlay measurement error induced by mark profile asymmetry being reduced, this technology is expected to be as accurate and precise as scatterometry technologies.

Bite marks on skin and clay: A comparative analysis

Directory of Open Access Journals (Sweden)

R.K. Gorea

2014-12-01

Full Text Available Bite marks are always unique because teeth are distinctive. Bite marks are often observed at the crime scene in sexual and in physical assault cases on the skin of the victims and sometimes on edible leftovers in burglary cases. This piece of evidence is often ignored, but if properly harvested and investigated, bite marks may prove useful in apprehending and successfully prosecuting the criminals. Due to the importance of bite marks, we conducted a progressive randomised experimental study conducted on volunteers. A total of 188 bite marks on clay were studied. Based on these findings, 93.34% of the volunteers could be identified from the bite marks on the clay. In addition, 201 impressions on skin were studied, and out of these cases, 41.01% of the same volunteers could be identified based on the bite mark impressions on the skin.

The subjective experience of psychiatric hospitalization : a case study approach / Mark Edward de la Rey

OpenAIRE

De la Rey, Mark Edward

2006-01-01

The aim of the research was to explore the subjective experience of patients admitted to a psychiatric hospital. Sub-aims were to explore how these experiences relate to self management, stress and psychological well-being. This study was motivated by research literature that documents a wide variety of negative experiences by patients. A recent psychiatric patient survey conducted in England and Wales (Mind, 2004) found that more than 50% of respondents indicated that hospital...

Determining predator identity from attack marks left in model caterpillars: guidelines for best practice

Czech Academy of Sciences Publication Activity Database

Low, P. A.; Sam, Kateřina; McArthur, C.; Posa, M. R. C.; Hochuli, D. F.

2014-01-01

Roč. 152, č. 2 (2014), s. 120-126 ISSN 0013-8703 R&D Projects: GA ČR GA206/09/0115; GA ČR GD206/08/H044 Grant - others:University of Sydney Animal Ethics(AU) L04/6-2012/3/5792 Institutional support: RVO:60077344 Keywords : artificial prey * attack marks * insect herbivores Subject RIV: EH - Ecology, Behaviour Impact factor: 1.616, year: 2014 http://onlinelibrary.wiley.com/doi/10.1111/eea.12207/pdf

Estimating population parameters of longsnout seahorses, Hippocampus reidi (Teleostei: Syngnathidae through mark-recapture

Directory of Open Access Journals (Sweden)

Alexandre C. Siqueira

2017-12-01

Full Text Available ABSTRACT Estimating population parameters is essential for understanding the ecology of species, which ultimately helps to assess their conservation status. The seahorse Hippocampus reidi is directly exposed to anthropogenic threats along the Brazilian coast, but the species still figures as Data Deficient (DD at IUCN’s Red List. To provide better information on the ecology of this species, we studied how population parameters vary over time in a natural subtropical environment. By combing mark-recapture models for open and closed populations, we estimated abundance, survival rate, emigration probability, and capture probability. We marked 111 individuals, which showed a 1:1 sex ratio, and an average size of 10.5 cm. The population showed high survival rate, low temporary emigration probability and variable capture probability and abundance. Our models considering relevant biological criteria illuminate the relatively poorly known population ecology and life history of seahorses. It is our hope that this study inspires the use of mark-recapture methods in other populations of H. reidi in a collective effort to properly assess their conservation status.

Gender Ideology in The Diary Of Adam And Eve by Mark Twain

Directory of Open Access Journals (Sweden)

Paramita Ayuningtyas

2011-04-01

Full Text Available This article aims to show that behind the new version of Genesis by Mark Twain in his novel The Diary of Adam and Eve, there are some patriarchal principles that appear in it. It can be seen from the characterizations of Adam and Eve. By using some concepts from feminism and also focusing on the context of the novel, the analysis shows that patriarchal stereotypes about gender are applied in constructing the characters of Adam and Eve. Not only the content, but the form of the diary is also analyzed with the same method, and the same result is found. Therefore, it can be concluded that in spite of his progressiveness, Mark Twain still held patriarchal values in re-interpreting the tale of human creation.   

49 CFR 172.317 - KEEP AWAY FROM HEAT handling mark.

Science.gov (United States)

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false KEEP AWAY FROM HEAT handling mark. 172.317 Section... REQUIREMENTS, AND SECURITY PLANS Marking § 172.317 KEEP AWAY FROM HEAT handling mark. (a) General. For... of Division 5.2 must be marked with the KEEP AWAY FROM HEAT handling mark specified in this section...

Mark Raidpere portreefotod Kielis

Index Scriptorium Estoniae

1999-01-01

Kieli Linnagaleriis avatud 2. Ars Baltica fototriennaalil 'Can You Hear Me?' esindab Eestit Mark Raidpere seeriaga 'Portreed 1998'. Näituse Eesti-poolne kuraator Anu Liivak, kataloogiteksti kirjutas Anders Härm. Tuntumaid osalejaid triennaalil Wolfgang Tillmans

Mark 1 Test Facility

Data.gov (United States)

Federal Laboratory Consortium — The Mark I Test Facility is a state-of-the-art space environment simulation test chamber for full-scale space systems testing. A $1.5M dollar upgrade in fiscal year...

Mark Raidpere näitused Pariisis ja Napolis / Mark Raidpere ; interv. Harry Liivrand

Index Scriptorium Estoniae

Raidpere, Mark

2008-01-01

Mark Raidpere videod "Vekovka", "Dedication / Pühendus", "Majestoso Mystico" näitusel Pariisis Michel Reini galeriis. Osaleb koos saksa fotograafi Sven Johnega näitusel Napolis. Kreekas Thessalonikis valminud filmist "1:1:1"

SUBJECTIVITY: SOCIAL REPRESENTATION OF THE FAMILY

Directory of Open Access Journals (Sweden)

Lourdete Rejane Ferro Zago

2013-09-01

Full Text Available The family, first family group of human beings, is the collective dimension of human existence and becomes responsible for the formation of the first social identity, as well as the constitution of subjectivity. Subjectivity is the inner world of each and every human being. This inner world is made up of emotions, feelings and thoughts. It is through this inner world that the individual relates to the social world, appointed by the outside world. This relationship follows the individual characteristics that mark the individual as unique, originated in shaping the individual, when they built the knowledge and beliefs. social representation as a form of knowledge, socially elaborated, shared with a practical purpose, contributing to the construction of a common reality to a social group. Is thus built up the social representation of the family.

Macrophage inflammatory protein-1α shows predictive value as a risk marker for subjects and sites vulnerable to bone loss in a longitudinal model of aggressive periodontitis.

Directory of Open Access Journals (Sweden)

Daniel H Fine

Full Text Available Improved diagnostics remains a fundamental goal of biomedical research. This study was designed to assess cytokine biomarkers that could predict bone loss (BL in localized aggressive periodontitis. 2,058 adolescents were screened. Two groups of 50 periodontally healthy adolescents were enrolled in the longitudinal study. One group had Aggregatibacter actinomycetemcomitans (Aa, the putative pathogen, while the matched cohort did not. Cytokine levels were assessed in saliva and gingival crevicular fluid (GCF. Participants were sampled, examined, and radiographed every 6 months for 2-3 years. Disease was defined as radiographic evidence of BL. Saliva and GCF was collected at each visit, frozen, and then tested retrospectively after detection of BL. Sixteen subjects with Aa developed BL. Saliva from Aa-positive and Aa-negative healthy subjects was compared to subjects who developed BL. GCF was collected from 16 subjects with BL and from another 38 subjects who remained healthy. GCF from BL sites in the 16 subjects was compared to healthy sites in these same subjects and to healthy sites in subjects who remained healthy. Results showed that cytokines in saliva associated with acute inflammation were elevated in subjects who developed BL (i.e., MIP-1α MIP-1β IL-α, IL-1β and IL-8; p<0.01. MIP-1α was elevated 13-fold, 6 months prior to BL. When MIP-1α levels were set at 40 pg/ml, 98% of healthy sites were below that level (Specificity; whereas, 93% of sites with BL were higher (Sensitivity, with comparable Predictive Values of 98%; p<0.0001; 95% C.I. = 42.5-52.7. MIP-1α consistently showed elevated levels as a biomarker for BL in both saliva and GCF, 6 months prior to BL. MIP-1α continues to demonstrate its strong candidacy as a diagnostic biomarker for both subject and site vulnerability to BL.

Association analysis of KIT, MITF, and PAX3 variants with white markings in Spanish horses.

Science.gov (United States)

Negro, S; Imsland, F; Valera, M; Molina, A; Solé, M; Andersson, L

2017-06-01

Several variants in the KIT, PAX3 and MITF genes have previously been associated with white markings in horses. In this study, we examined eight variants of these genes in 70 Menorca Purebred horses (PRMe, only black solid-coloured horses) and 70 Spanish Purebred horses (PRE, different coat colour patterns) that were scored for the extent of white markings. A maximum-likelihood chi-square test, logistic regression model and ridge regression analyses showed that a missense mutation (p.Arg682His) in KIT was associated with white facial markings (P horses. The relative contribution of this variant to white markings in PRMe horses was estimated at 47.6% (head) and 43.4% (total score). In PRE horses, this variant was also associated with hindlimb scores (P T intronic variant located 29.9 kb downstream from the transcription start site of the MITF gene was associated with less white markings on forelimbs (P horses, with a relative contribution of 63.9%, whereas in PRE horses this variant was associated with white facial markings (P horses, providing breeders with an opportunity to use genetic testing to aid in breeding for their desired level of white markings. © 2017 Stichting International Foundation for Animal Genetics.

Association of a trait-like bias towards the perception of negative subjective life events with risk of developing premenstrual symptoms.

Science.gov (United States)

Gonda, Xenia; Fountoulakis, Konstantinos N; Csukly, Gabor; Telek, Tamas; Pap, Dorottya; Rihmer, Zoltan; Bagdy, Gyorgy

2010-04-16

Premenstrual symptoms affect the majority of healthy women. Premenstrual symptomatology has earlier been linked to stress and a state-like alteration in the perception of life events in the late-luteal phase of the menstrual cycle. We hypothesised that there is also a trait-like negative bias in the perception of life events evident throughout the whole cycle which is associated with the likelihood to manifest more marked symptoms in the late-luteal phase of the cycle. 88 healthy women completed the PRISM calendar for three consecutive cycles and the Objective and Subjective Event Checklist during the follicular phase of the first cycle. Association between PRISM score change from the follicular through the late-luteal phase and life event variables was investigated by Generalized Linear Model Analysis (GENMOD). The PRISM score change showed a significant negative association with the ratio of positive subjective life events and a significant positive association with the ratio of negative subjective life events. There were no significant results in case of the objective life events. Our results indicate that women manifesting a more marked increase of symptoms from the late follicular through the late-luteal phase of the menstrual cycle are more likely to notice negative subjective life events and less likely to notice positive subjective life events. This suggest a trait-like negative bias in the perception of life events present throughout the whole reproductive cycle which may play an important role in the emergence of premenstrual symptoms. Copyright 2010 Elsevier Inc. All rights reserved.

Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hot Spots

Science.gov (United States)

Wu, Zhen; Fallahi, Mohammad; Ouizem, Souad; Liu, Qin; Li, Weimin; Costi, Roberta; Roush, William R.; Bois, Philippe R. J.

2016-01-01

ABSTRACT Meiotic recombination initiates following the formation of DNA double-strand breaks (DSBs) by the Spo11 endonuclease early in prophase I, at discrete regions in the genome coined “hot spots.” In mammals, meiotic DSB site selection is directed in part by sequence-specific binding of PRDM9, a polymorphic histone H3 (H3K4Me3) methyltransferase. However, other chromatin features needed for meiotic hot spot specification are largely unknown. Here we show that the recombinogenic cores of active hot spots in mice harbor several histone H3 and H4 acetylation and methylation marks that are typical of open, active chromatin. Further, deposition of these open chromatin-associated histone marks is dynamic and is manifest at spermatogonia and/or pre-leptotene-stage cells, which facilitates PRDM9 binding and access for Spo11 to direct the formation of DSBs, which are initiated at the leptotene stage. Importantly, manipulating histone acetylase and deacetylase activities established that histone acetylation marks are necessary for both hot spot activity and crossover resolution. We conclude that there are functional roles for histone acetylation marks at mammalian meiotic recombination hot spots. PMID:27821479

Z0 physics from the Mark II at the SLC [SLAC Linear Collider

International Nuclear Information System (INIS)

Abrams, G.S.

1989-06-01

The MARK II detector has started to take data at the new SLAC Linear Collider. The novel aspects of the accelerator and of the MARK II are briefly described. Displays of event pictures from some of the early-on data are presented to illustrate the quality of the data. A first presentation of the results of an energy scan near the Z 0 mass that is currently in progress shows the expected resonant enhancement near 91 GeV. 2 refs., 23 figs., 1 tab

EcoMark 2.0

DEFF Research Database (Denmark)

Guo, Chenjuan; Yang, Bin; Andersen, Ove

2015-01-01

Eco-routing is a simple yet effective approach to substantially reducing the environmental impact, e.g., fuel consumption and greenhouse gas (GHG) emissions, of vehicular transportation. Eco-routing relies on the ability to reliably quantify the environmental impact of vehicles as they travel...... in a spatial network. The procedure of quantifying such vehicular impact for road segments of a spatial network is called eco-weight assignment. EcoMark 2.0 proposes a general framework for eco-weight assignment to enable eco-routing. It studies the abilities of six instantaneous and five aggregated models......, and experiments for assessing the utility of the impact models in assigning eco-weights. The application of EcoMark 2.0 indicates that the instantaneous model EMIT and the aggregated model SIDRA-Running are suitable for assigning eco-weights under varying circumstances. In contrast, other instantaneous models...

Interview with Mark Watson

Directory of Open Access Journals (Sweden)

Katy Shaw

2016-04-01

Full Text Available Mark Watson is a British comedian and novelist. His five novels to date – 'Bullet Points' (2004, 'A Light-Hearted Look At Murder' (2007, 'Eleven' (2010, 'The Knot' (2012 and 'Hotel Alpha' (2014 – explore human relationships and communities in contemporary society. His latest novel Hotel Alpha tells the story of an extraordinary hotel in London and two mysterious disappearances that raise questions no one seems willing to answer. External to the novel, readers can also discover more about the hotel and its inhabitants in one hundred extra stories that expand the world of the novel and can be found at http://www.hotelalphastories.com. In conversation here with Dr Katy Shaw, Mark offers some reflections on his writing process, the field of contemporary literature, and the vitality of the novel form in the twenty-first century.

Recognition in context: Implications for trade mark law.

Science.gov (United States)

Humphreys, Michael S; McFarlane, Kimberley A; Burt, Jennifer S; Kelly, Sarah J; Weatherall, Kimberlee G; Burrell, Robert G

2017-10-01

Context effects in recognition have played a major role in evaluating theories of recognition. Understanding how context impacts recognition is also important for making sound trade mark law. Consumers attempting to discriminate between the brand they are looking for and a look-alike product often have to differentiate products which share a great deal of common context: positioning on the supermarket shelf, the type of store, aspects of the packaging, or brand claims. Trade mark and related laws aim to protect brands and reduce consumer confusion, but courts assessing allegations of trade mark infringement often lack careful empirical evidence concerning the impact of brand and context similarity, and, in the absence of such evidence, make assumptions about how consumers respond to brands that downplay the importance of context and focus on the similarity of registered marks. The experiments reported in this paper aimed to test certain common assumptions in trade mark law, providing evidence that shared context can cause mistakes even where brand similarity is low.

Wavefront holoscopy: application of digital in-line holography for the inspection of engraved marks in progressive addition lenses.

Science.gov (United States)

Perucho, Beatriz; Micó, Vicente

2014-01-01

Progressive addition lenses (PALs) are engraved with permanent marks at standardized locations in order to guarantee correct centering and alignment throughout the manufacturing and mounting processes. Out of the production line, engraved marks provide useful information about the PAL as well as act as locator marks to re-ink again the removable marks. Even though those marks should be visible by simple visual inspection with the naked eye, engraving marks are often faint and weak, obscured by scratches, and partially occluded and difficult to recognize on tinted or antireflection-coated lenses. Here, we present an extremely simple optical device (named as wavefront holoscope) for visualization and characterization of permanent marks in PAL based on digital in-line holography. Essentially, a point source of coherent light illuminates the engraved mark placed just before a CCD camera that records a classical Gabor in-line hologram. The recorded hologram is then digitally processed to provide a set of high-contrast images of the engraved marks. Experimental results are presented showing the applicability of the proposed method as a new ophthalmic instrument for visualization and characterization of engraved marks in PALs.

Naturalization, reciprocity and marks of marital violence: male defendants' perceptions

Directory of Open Access Journals (Sweden)

Gilvânia Patrícia do Nascimento Paixão

Full Text Available ABSTRACT Objective: to analyze male criminals' perception about marital violence. Method: An exploratory, descriptive, qualitative study undertaken with 23 men who were criminally prosecuted for marital violence. A multimethod data collection was conducted, with individual interview and focal group techniques combined, between May and December 2015. The data collected were initially categorized using the NVIVO® 11 software program, and then organized using the Collective Subject Discourse method. Results: the collective discourses reveal that, in the male's perception, conjugal violence is inherent in a marital relationships: it is a private, reciprocal problem that leaves body marks. Conclusion: gender dissymmetry as a social construct is evidenced, signaling the need to create spaces for reflection and re-signification of men and women, from a gender perspective.

Unequal Probability Marking Approach to Enhance Security of Traceback Scheme in Tree-Based WSNs.

Science.gov (United States)

Huang, Changqin; Ma, Ming; Liu, Xiao; Liu, Anfeng; Zuo, Zhengbang

2017-06-17

Fog (from core to edge) computing is a newly emerging computing platform, which utilizes a large number of network devices at the edge of a network to provide ubiquitous computing, thus having great development potential. However, the issue of security poses an important challenge for fog computing. In particular, the Internet of Things (IoT) that constitutes the fog computing platform is crucial for preserving the security of a huge number of wireless sensors, which are vulnerable to attack. In this paper, a new unequal probability marking approach is proposed to enhance the security performance of logging and migration traceback (LM) schemes in tree-based wireless sensor networks (WSNs). The main contribution of this paper is to overcome the deficiency of the LM scheme that has a higher network lifetime and large storage space. In the unequal probability marking logging and migration (UPLM) scheme of this paper, different marking probabilities are adopted for different nodes according to their distances to the sink. A large marking probability is assigned to nodes in remote areas (areas at a long distance from the sink), while a small marking probability is applied to nodes in nearby area (areas at a short distance from the sink). This reduces the consumption of storage and energy in addition to enhancing the security performance, lifetime, and storage capacity. Marking information will be migrated to nodes at a longer distance from the sink for increasing the amount of stored marking information, thus enhancing the security performance in the process of migration. The experimental simulation shows that for general tree-based WSNs, the UPLM scheme proposed in this paper can store 1.12-1.28 times the amount of stored marking information that the equal probability marking approach achieves, and has 1.15-1.26 times the storage utilization efficiency compared with other schemes.

Trade Mark Cluttering: An Exploratory Report Commissioned by UKIPO

OpenAIRE

von Graevenitz, Georg; Greenhalgh, Christine; Helmers, Christian; Schautschick, Philipp

2012-01-01

This report explores the problem of “cluttering” of trade mark registers. The report consists of two parts: the first presents a conceptual discussion of “cluttering” of trade mark registers. The second part provides an exploratory empirical analysis of trade mark applications at the UK Intellectual Property Office (UKIPO) and the European trade mark office (OHIM). This part contains results of a descriptive and an econometric analysis. According to our definition, cluttering arises where fir...

Carbon Dioxide Washout Testing Using Various Inlet Vent Configurations in the Mark-III Space Suit

Science.gov (United States)

Korona, F. Adam; Norcross, Jason; Conger, Bruce; Navarro, Moses

2014-01-01

Requirements for using a space suit during ground testing include providing adequate carbon dioxide (CO2) washout for the suited subject. Acute CO2 exposure can lead to symptoms including headache, dyspnea, lethargy, and eventually unconsciousness or even death. Symptoms depend on several factors including inspired partial pressure of CO2 (ppCO2), duration of exposure, metabolic rate of the subject, and physiological differences between subjects. Computational Fluid Dynamics (CFD) analysis has predicted that the configuration of the suit inlet vent has a significant effect on oronasal CO2 concentrations. The main objective of this test was to characterize inspired oronasal ppCO2 for a variety of inlet vent configurations in the Mark-III suit across a range of workload and flow rates. Data and trends observed during testing along with refined CFD models will be used to help design an inlet vent configuration for the Z-2 space suit. The testing methodology used in this test builds upon past CO2 washout testing performed on the Z-1 suit, Rear Entry I-Suit, and the Enhanced Mobility Advanced Crew Escape Suit. Three subjects performed two test sessions each in the Mark-III suit to allow for comparison between tests. Six different helmet inlet vent configurations were evaluated during each test session. Suit pressure was maintained at 4.3 psid. Suited test subjects walked on a treadmill to generate metabolic workloads of approximately 2000 and 3000 BTU/hr. Supply airflow rates of 6 and 4 actual cubic feet per minute were tested at each workload. Subjects wore an oronasal mask with an open port in front of the mouth and were allowed to breathe freely. Oronasal ppCO2 was monitored real-time via gas analyzers with sampling tubes connected to the oronasal mask. Metabolic rate was calculated from the CO2 production measured by an additional gas analyzer at the air outlet from the suit. Real-time metabolic rate measurements were used to adjust the treadmill workload to meet

32 CFR 2400.16 - Derivative classification markings.

Science.gov (United States)

2010-07-01

... SECURITY PROGRAM Derivative Classification § 2400.16 Derivative classification markings. (a) Documents... 32 National Defense 6 2010-07-01 2010-07-01 false Derivative classification markings. 2400.16..., as described in § 2400.12 of this part, the information may not be used as a basis for derivative...

Multiplexing clonality: combining RGB marking and genetic barcoding

Science.gov (United States)

Cornils, Kerstin; Thielecke, Lars; Hüser, Svenja; Forgber, Michael; Thomaschewski, Michael; Kleist, Nadja; Hussein, Kais; Riecken, Kristoffer; Volz, Tassilo; Gerdes, Sebastian; Glauche, Ingmar; Dahl, Andreas; Dandri, Maura; Roeder, Ingo; Fehse, Boris

2014-01-01

RGB marking and DNA barcoding are two cutting-edge technologies in the field of clonal cell marking. To combine the virtues of both approaches, we equipped LeGO vectors encoding red, green or blue fluorescent proteins with complex DNA barcodes carrying color-specific signatures. For these vectors, we generated highly complex plasmid libraries that were used for the production of barcoded lentiviral vector particles. In proof-of-principle experiments, we used barcoded vectors for RGB marking of cell lines and primary murine hepatocytes. We applied single-cell polymerase chain reaction to decipher barcode signatures of individual RGB-marked cells expressing defined color hues. This enabled us to prove clonal identity of cells with one and the same RGB color. Also, we made use of barcoded vectors to investigate clonal development of leukemia induced by ectopic oncogene expression in murine hematopoietic cells. In conclusion, by combining RGB marking and DNA barcoding, we have established a novel technique for the unambiguous genetic marking of individual cells in the context of normal regeneration as well as malignant outgrowth. Moreover, the introduction of color-specific signatures in barcodes will facilitate studies on the impact of different variables (e.g. vector type, transgenes, culture conditions) in the context of competitive repopulation studies. PMID:24476916

Marking for Structure using Boolean Feedback | Louw | Journal for ...

African Journals Online (AJOL)

This paper presents evidence that marking student texts with well considered checklists is more effective than marking by hand. An experiment conducted on first-year students illustrated that the checklists developed to mark introductions, conclusions and paragraphs yielded better revision results than handwritten ...

Tooth-marked small theropod bone: an extremely rare trace

DEFF Research Database (Denmark)

Jacobsen, Aase Roland

2001-01-01

Tooth-marked dinosaur bones provide insight into feeding behaviours and biting strategies of theropod dinosaurs. The majority of theropod tooth marks reported to date have been found on herbivorous dinosaur bones, although some tyrannosaurid bones with tooth marks have also been reported. In 1988...

A case of marked short-neck with fusion of cervical vertebrae in a Holstein cow

International Nuclear Information System (INIS)

Ogawa, J.; Ando, T.; Otsuka, H.; Paku, T.; Yoshioka, I.; Saruyama, Y.; Yamada, H.; Iso, H.; Oyamada, T.; Watanabe, D.

2007-01-01

An 11-month old Holstein cow with congenitally shortened neck was subjected to clinical, radiographic and myelographic examination, and also autopsy and histopathological examination. Skeletal preparations of the cervical region were made to investigate the abnormality of the vertebrae. The cow was growing normally, and no critical neurological signs were observed. Radiographic examination showed marked kyphosis of the cervical spine, and fusion of posterior cervical vertebrae was suspected. Myelographic examination showed curvature of the spinal cord, but no narrowing at any part. Atrophy, hyaline degeneration, and hydropic degeneration of muscle fibers were seen in the dorsal part of the cervical region in the histopathological examination, but there was no abnormality in the cervical spinal cord. Deformation, fusion, and hypoplasia of the cervical vertebrae and posterior thoracic vertebrae were observed. It is suggested that in the organ system-wise classification of congenital abnormalities, this may be classified as a case of defective vertebrae with the coexisting congenital anomalies of kyphosis, scoliosis and vertebral fusion. The cause of this defect was not clear, but the observed vertebral fusion and hypoplasia indicated defective development of the vertebral segment during the early fetal stage

7 CFR 920.303 - Container marking regulations.

Science.gov (United States)

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Container marking regulations. 920.303 Section 920.303... Miscellaneous Provisions § 920.303 Container marking regulations. No handler shall ship any kiwifruit except in accordance with the following terms and conditions: (a) Each package or container of kiwifruit shall bear on...

Computer animations of color markings reveal the function of visual threat signals in Neolamprologus pulcher.

Science.gov (United States)

Balzarini, Valentina; Taborsky, Michael; Villa, Fabienne; Frommen, Joachim G

2017-02-01

Visual signals, including changes in coloration and color patterns, are frequently used by animals to convey information. During contests, body coloration and its changes can be used to assess an opponent's state or motivation. Communication of aggressive propensity is particularly important in group-living animals with a stable dominance hierarchy, as the outcome of aggressive interactions determines the social rank of group members. Neolamprologus pulcher is a cooperatively breeding cichlid showing frequent within-group aggression. Both sexes exhibit two vertical black stripes on the operculum that vary naturally in shape and darkness. During frontal threat displays these patterns are actively exposed to the opponent, suggesting a signaling function. To investigate the role of operculum stripes during contests we manipulated their darkness in computer animated pictures of the fish. We recorded the responses in behavior and stripe darkness of test subjects to which these animated pictures were presented. Individuals with initially darker stripes were more aggressive against the animations and showed more operculum threat displays. Operculum stripes of test subjects became darker after exposure to an animation exhibiting a pale operculum than after exposure to a dark operculum animation, highlighting the role of the darkness of this color pattern in opponent assessment. We conclude that (i) the black stripes on the operculum of N. pulcher are a reliable signal of aggression and dominance, (ii) these markings play an important role in opponent assessment, and (iii) 2D computer animations are well suited to elicit biologically meaningful short-term aggressive responses in this widely used model system of social evolution.

27 CFR 19.612 - Authorized abbreviations to identify marks.

Science.gov (United States)

2010-04-01

... T Tax Determined TD Wine Spirits Addition WSA (Sec. 201, Pub. L. 85-859, 72 Stat. 1360, as amended... TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Containers and Marks... to identify certain marks: Mark Abbreviation Completely Denatured Alcohol CDA Distilled Spirits...

The national hydrologic bench-mark network

Science.gov (United States)

Cobb, Ernest D.; Biesecker, J.E.

1971-01-01

The United States is undergoing a dramatic growth of population and demands on its natural resources. The effects are widespread and often produce significant alterations of the environment. The hydrologic bench-mark network was established to provide data on stream basins which are little affected by these changes. The network is made up of selected stream basins which are not expected to be significantly altered by man. Data obtained from these basins can be used to document natural changes in hydrologic characteristics with time, to provide a better understanding of the hydrologic structure of natural basins, and to provide a comparative base for studying the effects of man on the hydrologic environment. There are 57 bench-mark basins in 37 States. These basins are in areas having a wide variety of climate and topography. The bench-mark basins and the types of data collected in the basins are described.

46 CFR 160.077-31 - PFD Marking.

Science.gov (United States)

2010-10-01

... Marking. (a) General. Each hybrid PFD must be marked with the applicable information required by this... text of special purpose or limitation and vessel(s) or vessel type(s), noted on approval certificate... and be presented in the exact order shown: Type [II, III, or V, as applicable] PFD [See paragraph (k...

9 CFR 590.418 - Supervision of marking and packaging.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Supervision of marking and packaging...) Identifying and Marking Product § 590.418 Supervision of marking and packaging. (a) Evidence of label approval... has on file evidence that such official identification or packaging material bearing such official...

Lane marking detection based on waveform analysis and CNN

Science.gov (United States)

Ye, Yang Yang; Chen, Hou Jin; Hao, Xiao Li

2017-06-01

Lane markings detection is a very important part of the ADAS to avoid traffic accidents. In order to obtain accurate lane markings, in this work, a novel and efficient algorithm is proposed, which analyses the waveform generated from the road image after inverse perspective mapping (IPM). The algorithm includes two main stages: the first stage uses an image preprocessing including a CNN to reduce the background and enhance the lane markings. The second stage obtains the waveform of the road image and analyzes the waveform to get lanes. The contribution of this work is that we introduce local and global features of the waveform to detect the lane markings. The results indicate the proposed method is robust in detecting and fitting the lane markings.

UID...Leaving Its Mark on the Universe

Science.gov (United States)

Schramm, Harry F., Jr.

2008-01-01

Since 1975 bar codes on products at the retail counter have been accepted as the standard for entering product identity for price determination. Since the beginning of the 21 st century, the Data Matrix symbol has become accepted as the bar code format that is marked directly on a part, assembly or product that is durable enough to identify that item for its lifetime. NASA began the studies for direct part marking Data Matrix symbols on parts during the Return to Flight activities after the Challenger Accident. Over the 20 year period that has elapsed since Challenger, a mountain of studies, analyses and focused problem solutions developed by and for NASA have brought about world changing results. NASA Technical Standard 6002 and NASA Handbook 6003 for Direct Part Marking Data Matrix Symbols on Aerospace Parts have formed the basis for most other standards on part marking internationally. NASA and its commercial partners have developed numerous products and methods that addressed the difficulties of collecting part identification in aerospace operations. These products enabled the marking of Data Matrix symbols in virtually every situation and the reading of symbols at great distances, severe angles, under paint and in the dark without a light. Even unmarkable delicate parts now have a process to apply a chemical mixture, recently trademarked as Nanocodes, that can be converted to Data Matrix information through software. The accompanying intellectual property is protected by ten patents, several of which are licensed. Direct marking Data Matrix on NASA parts dramatically decreases data entry errors and the number of parts that go through their life cycle unmarked, two major threats to sound configuration management and flight safety. NASA is said to only have people and stuff with information connecting them. Data Matrix is one of the most significant improvements since Challenger to the safety and reliability of that connection.

UID....Now That's Gonna Leave A Mark

Science.gov (United States)

Schramm, Harry F., Jr.

2008-01-01

Since 1975 bar codes on products at the retail counter have been accepted as the standard for entering product identity for price determination. Since the beginning of the 21 st century, the Data Matrix symbol has become accepted as the bar code format that is marked directly on a part, assembly or product that is durable enough to identify that item for its lifetime. NASA began the studies for direct part marking Data Matrix symbols on parts during the Return to Flight activities after the Challenger Accident. Over the 20 year period that has elapsed since Challenger, a mountain of studies, analyses and focused problem solutions developed by and for NASA have brought about world changing results. NASA Technical Standard 6002 and NASA Handbook 6003 for Direct Part Marking Data Matrix Symbols on Aerospace Parts have formed the basis for most other standards on part marking internationally. NASA and its commercial partners have developed numerous products and methods that addressed the difficulties of collecting part identification in aerospace operations. These products enabled the marking of Data Matrix symbols in virtually every situation and the reading of symbols at great distances, severe angles, under paint and in the dark without a light. Even unmarkable delicate parts now have a process to apply a chemical mixture, recently trademarked as Nanocodes, that can be converted to Data Matrix information through software. The accompanying intellectual property is protected by ten patents, several of which are licensed. Direct marking Data Matrix on NASA parts dramatically decreases data entry errors and the number of parts that go through their life cycle unmarked, two major threats to sound configuration management and flight safety. NASA is said to only have people and stuff with information connecting them. Data Matrix is one of the most significant improvements since Challenger to the safety and reliability of that connection.

Otolith marking of juvenile shortnose gar by immersion in oxytetracycline

Science.gov (United States)

Snow, Richard A.; Long, James M.

2017-01-01

Oxytetracycline (OTC) has been used to mark a variety of fish species at multiple developmental stages; however, there is little information on batch-marking Lepisosteidae. Juvenile Shortnose Gar Lepisosteus platostomus (53 ± 3 mm TL) were seined from an Oklahoma State University research pond and transported to the Oklahoma Fishery Research Lab. Juvenile Shortnose Gar were exposed to a range of OTC concentrations—0, 500, 600, and 700 mg/L—for 4, 5, or 6 h. Lapillus and sagitta otoliths were examined 14 d postexposure for mark presence and evaluation using fluorescent microscopy. Overall, 93.3% of otoliths exposed to OTC exhibited a mark. Concentration of OTC affected the mean mark quality, whereas duration and otolith type examined did not. However, as concentration increased, so did mortality, suggesting a balance is needed to achieve marking goals. Based on our findings, batch marking of Shortnose Gar can be successful at OTC concentrations from 500 to 700 mg/L for 4–6 h, although mark quality may vary and mortality rates increase at the higher concentrations and longer durations.

Estimating sample size for landscape-scale mark-recapture studies of North American migratory tree bats

Science.gov (United States)

Ellison, Laura E.; Lukacs, Paul M.

2014-01-01

Concern for migratory tree-roosting bats in North America has grown because of possible population declines from wind energy development. This concern has driven interest in estimating population-level changes. Mark-recapture methodology is one possible analytical framework for assessing bat population changes, but sample size requirements to produce reliable estimates have not been estimated. To illustrate the sample sizes necessary for a mark-recapture-based monitoring program we conducted power analyses using a statistical model that allows reencounters of live and dead marked individuals. We ran 1,000 simulations for each of five broad sample size categories in a Burnham joint model, and then compared the proportion of simulations in which 95% confidence intervals overlapped between and among years for a 4-year study. Additionally, we conducted sensitivity analyses of sample size to various capture probabilities and recovery probabilities. More than 50,000 individuals per year would need to be captured and released to accurately determine 10% and 15% declines in annual survival. To detect more dramatic declines of 33% or 50% survival over four years, then sample sizes of 25,000 or 10,000 per year, respectively, would be sufficient. Sensitivity analyses reveal that increasing recovery of dead marked individuals may be more valuable than increasing capture probability of marked individuals. Because of the extraordinary effort that would be required, we advise caution should such a mark-recapture effort be initiated because of the difficulty in attaining reliable estimates. We make recommendations for what techniques show the most promise for mark-recapture studies of bats because some techniques violate the assumptions of mark-recapture methodology when used to mark bats.

Radio-marking and in vivo imagery of oligonucleotides

International Nuclear Information System (INIS)

Kuehnast, Bertrand

2000-01-01

This research thesis is part of activities aimed at the development of new molecules like oligonucleotides. Its first objective was the development and validation of a marking method with fluorine-18 of oligonucleotides for their in-vivo pharmacological assessment with positron emission tomography (PET). Further investigations addressed the use of iodine-125 for oligonucleotide marking purpose. This radio-marking, and in vivo and ex vivo imagery techniques are described, and their potential is highlighted for the pharmacological assessment of different oligonucleotides

The amblyopic eye in subjects with anisometropia show increased saccadic latency in the delayed saccade task

Directory of Open Access Journals (Sweden)

Maciej ePerdziak

2014-10-01

Full Text Available The term amblyopia is used to describe reduced visual function in one eye (or both eyes, though not so often which cannot be fully improved by refractive correction and explained by the organic cause observed during regular eye examination. This developmental disorder of spatial vision affects about 2-5% of the population and is associated with abnormal visual experience (e.g. anisometropia, strabismus during infancy or early childhood. Several studies have shown prolongation of saccadic latency time in amblyopic eye. In our opinion, study of saccadic latency in the context of central vision deficits assessment, should be based on central retina stimulation. For this reason, we proposed saccade delayed task. It requires inhibitory processing for maintaining fixation on the central target until it disappears – what constitutes the GO signal for saccade. The experiment consisted of 100 trials for each eye and was performed under two viewing conditions: monocular amblyopic / non-dominant eye and monocular dominant eye. We examined saccadic latency in 16 subjects (mean age 30±11 years with anisometropic amblyopia (two subjects had also microtropia and in 17 control subjects (mean age 28±8 years. Participants were instructed to look at central (fixation target and when it disappears, to make the saccade toward the periphery (10 deg as fast as possible, either left or the right target. The study results have proved the significant difference in saccadic latency between the amblyopic (mean 262±48 ms and dominant (mean 237±45 ms eye, in anisometropic group. In the control group, the saccadic latency for dominant (mean 226±32ms and non-dominant (mean 230±29 ms eye was not significantly different.By the use of LATER (Linear Approach to the Threshold with Ergodic Rate decision model we interpret our findings as a decrease in accumulation of visual information acquired by means of central (affected retina in subjects with anisometropic amblyopia.

an extended pancreatic normal subjects and ~in pancreatItIs In ...

African Journals Online (AJOL)

function . . patIents. N. H. GILlNSKY, A. S. MEE, I. N. MARKS. Summary. Exocrine pancreatic response was evaluated in patients with varying degrees of pancreatic damage and in control subjects by ... hormones, the Lundh meal and an oral pancreatic function test .... is any different from that of the cells in me normal gland.

Field manual for identifying and preserving high-water mark data

Science.gov (United States)

Feaster, Toby D.; Koenig, Todd A.

2017-09-26

This field manual provides general guidance for identifying and collecting high-water marks and is meant to be used by field personnel as a quick reference. The field manual describes purposes for collecting and documenting high-water marks along with the most common types of high-water marks. The manual provides a list of suggested field equipment, describes rules of thumb and best practices for finding high-water marks, and describes the importance of evaluating each high-water mark and assigning a numeric uncertainty value as part of the flagging process. The manual also includes an appendix of photographs of a variety of high-water marks obtained from various U.S. Geological Survey field investigations along with general comments about the logic for the assigned uncertainty values.

Survival and reproduction of radio-marked adult spotted owls.

Science.gov (United States)

C.C. Foster; E.D. Forsman; E.C. Meslow; G.S. Miller; J.A. Reid; F.F. Wagner; A.B. Carey; J.B. Lint

1992-01-01

We compared survival, reproduction, and body mass of radio-marked and non radio-marked spotted owls (Strix occidentalis) to determine if backpack radios influenced reproduction or survival. In most study areas and years, there were no differences (P > 0.05) in survival of males and females or in survival of radio-marked versus banded owls. There...

THE CONTEMPORARY PORTUGUESE CHARACTER IN THE UNIVERSE OF A MULTILINGUAL SUBJECT WITH FRAGILE X SYNDROME

Directory of Open Access Journals (Sweden)

Isabela Barbosa do Rêgo Barros

2016-06-01

Full Text Available Associated often in autism by virtue of the similarity of symptoms (SCHWARTZMAN et al., 1995; DIAMENT; CYPEL, 1996, Fragile X Syndrome (FXS is characterized mainly by cognitive impairment accompanied by behavioral changes and sensorimotor, learning disability, physical impairment and language. This is marked by delay in its acquisition, omissions, substitutions and phonetic distortion, echolalia, holophrase, short sentences, pauses and hesitations, interjections and frequent monologues. This article aims to discuss the contemporary character of the Portuguese language and the identification process in the language in a multilingual context as key to the appropriation of a language by a subject diagnosed with FXS. We base our discussions on Enunciation theory of Emile Benveniste (2005, 2006 and studies of Silva (2009 which analyzes for a stated perspective regarding the language, language and subject. We realized that the Portuguese language was used on specific occasions, marking unique productions in Portuguese, classical German and German dialect Schwäbisch as effects of the operations of subject, indicating that education and ownership of a language is established in an identification relationship to the subject that makes use of it.

Bench-marking beam-beam simulations using coherent quadrupole effects

International Nuclear Information System (INIS)

Krishnagopal, S.; Chin, Y.H.

1992-06-01

Computer simulations are used extensively in the study of the beam-beam interaction. The proliferation of such codes raises the important question of their reliability, and motivates the development of a dependable set of bench-marks. We argue that rather than detailed quantitative comparisons, the ability of different codes to predict the same qualitative physics should be used as a criterion for such bench-marks. We use the striking phenomenon of coherent quadrupole oscillations as one such bench-mark, and demonstrate that our codes do indeed observe this behaviour. We also suggest some other tests that could be used as bench-marks

Bench-marking beam-beam simulations using coherent quadrupole effects

International Nuclear Information System (INIS)

Krishnagopal, S.; Chin, Y.H.

1992-01-01

Computer simulations are used extensively in the study of the beam-beam interaction. The proliferation of such codes raises the important question of their reliability, and motivates the development of a dependable set of bench-marks. We argue that rather than detailed quantitative comparisons, the ability of different codes to predict the same qualitative physics should be used as a criterion for such bench-marks. We use the striking phenomenon of coherent quadrupole oscillations as one such bench-mark, and demonstrate that our codes do indeed observe this behavior. We also suggest some other tests that could be used as bench-marks

The Information Literacy of Survey Mark Hunting: A Dialogue

Directory of Open Access Journals (Sweden)

Jennifer Galas

2016-11-01

Full Text Available In Brief: This article makes connections between the ACRL Framework for Information Literacy for Higher Education and the activity of survey mark hunting. After a brief review of the literature related to geographic information systems (GIS, information literacy, and gamification of learning, the authors enter into a dialogue in which they discover and describe the various ways information literacy is both required by and developed through the recreational activity of survey mark hunting. Through their dialogue they found that the activity of survey mark hunting relies on the construction of both information and its authority in ways contextualized within the communities that participate; that survey mark hunting is a conversation that builds on the past, where lived experience counts as evidence; and, that survey mark hunting is both a metaphor and embodied enactment of information literacy.

Searching via walking: How to find a marked clique of a complete graph using quantum walks

International Nuclear Information System (INIS)

Hillery, Mark; Reitzner, Daniel; Buzek, Vladimir

2010-01-01

We show how a quantum walk can be used to find a marked edge or a marked complete subgraph of a complete graph. We employ a version of a quantum walk, the scattering walk, which lends itself to experimental implementation. The edges are marked by adding elements to them that impart a specific phase shift to the particle as it enters or leaves the edge. If the complete graph has N vertices and the subgraph has K vertices, the particle becomes localized on the subgraph in O(N/K) steps. This leads to a quantum search that is quadratically faster than a corresponding classical search. We show how to implement the quantum walk using a quantum circuit and a quantum oracle, which allows us to specify the resources needed for a quantitative comparison of the efficiency of classical and quantum searches--the number of oracle calls.

Recognition of Damaged Arrow-Road Markings by Visible Light Camera Sensor Based on Convolutional Neural Network

Directory of Open Access Journals (Sweden)

Husan Vokhidov

2016-12-01

Full Text Available Automobile driver information as displayed on marked road signs indicates the state of the road, traffic conditions, proximity to schools, etc. These signs are important to insure the safety of the driver and pedestrians. They are also important input to the automated advanced driver assistance system (ADAS, installed in many automobiles. Over time, the arrow-road markings may be eroded or otherwise damaged by automobile contact, making it difficult for the driver to correctly identify the marking. Failure to properly identify an arrow-road marker creates a dangerous situation that may result in traffic accidents or pedestrian injury. Very little research exists that studies the problem of automated identification of damaged arrow-road marking painted on the road. In this study, we propose a method that uses a convolutional neural network (CNN to recognize six types of arrow-road markings, possibly damaged, by visible light camera sensor. Experimental results with six databases of Road marking dataset, KITTI dataset, Málaga dataset 2009, Málaga urban dataset, Naver street view dataset, and Road/Lane detection evaluation 2013 dataset, show that our method outperforms conventional methods.

Recognition of Damaged Arrow-Road Markings by Visible Light Camera Sensor Based on Convolutional Neural Network.

Science.gov (United States)

Vokhidov, Husan; Hong, Hyung Gil; Kang, Jin Kyu; Hoang, Toan Minh; Park, Kang Ryoung

2016-12-16

Automobile driver information as displayed on marked road signs indicates the state of the road, traffic conditions, proximity to schools, etc. These signs are important to insure the safety of the driver and pedestrians. They are also important input to the automated advanced driver assistance system (ADAS), installed in many automobiles. Over time, the arrow-road markings may be eroded or otherwise damaged by automobile contact, making it difficult for the driver to correctly identify the marking. Failure to properly identify an arrow-road marker creates a dangerous situation that may result in traffic accidents or pedestrian injury. Very little research exists that studies the problem of automated identification of damaged arrow-road marking painted on the road. In this study, we propose a method that uses a convolutional neural network (CNN) to recognize six types of arrow-road markings, possibly damaged, by visible light camera sensor. Experimental results with six databases of Road marking dataset, KITTI dataset, Málaga dataset 2009, Málaga urban dataset, Naver street view dataset, and Road/Lane detection evaluation 2013 dataset, show that our method outperforms conventional methods.

Recognition of Damaged Arrow-Road Markings by Visible Light Camera Sensor Based on Convolutional Neural Network

Science.gov (United States)

Vokhidov, Husan; Hong, Hyung Gil; Kang, Jin Kyu; Hoang, Toan Minh; Park, Kang Ryoung

2016-01-01

Automobile driver information as displayed on marked road signs indicates the state of the road, traffic conditions, proximity to schools, etc. These signs are important to insure the safety of the driver and pedestrians. They are also important input to the automated advanced driver assistance system (ADAS), installed in many automobiles. Over time, the arrow-road markings may be eroded or otherwise damaged by automobile contact, making it difficult for the driver to correctly identify the marking. Failure to properly identify an arrow-road marker creates a dangerous situation that may result in traffic accidents or pedestrian injury. Very little research exists that studies the problem of automated identification of damaged arrow-road marking painted on the road. In this study, we propose a method that uses a convolutional neural network (CNN) to recognize six types of arrow-road markings, possibly damaged, by visible light camera sensor. Experimental results with six databases of Road marking dataset, KITTI dataset, Málaga dataset 2009, Málaga urban dataset, Naver street view dataset, and Road/Lane detection evaluation 2013 dataset, show that our method outperforms conventional methods. PMID:27999301

Mark Antony’s Homoeroticism in Cicero’s second Philippic

Directory of Open Access Journals (Sweden)

Bruna Fernanda Abreu

2017-06-01

Full Text Available Considering the concept of homosexuality in the ancient Rome, we attempt to analise how Cicero expose the Mark Antony’s “homosexuality” in his second Philippic. This speech is characterized by political and, mainly, personal accusations from Cicero to Mark Antony, and the Mark Antony’s passivity in his intercourses can be considered a topos of this invective speech.

NOMINAL MARKING SYSTEM OF BAHASA MANGGARAI AND ITS INTERRELATION TO NAMING SYSTEM OF ENTITIES: A CULTURAL LINGUISTIC STUDY

Directory of Open Access Journals (Sweden)

Kletus Erom

2012-11-01

Full Text Available This study analyzes the cultural imagery of the Manggaraian SpeechCommunities (MSC in “Nominal Marking System (NMS of Bahasa Manggaraiand Its Interrelation with Naming Systems of Entity (NSE: A CulturalLinguistic Study”. The result of the analysis is useful for both the academic worldand the life of the society, especially the MSC.The study conducted in Manggarai Regency, Flores, East Nusa TenggaraProvince, is qualitative. The data were obtained through observation, elicitation,interview, documentation study, listening, and note taking. For this reason, a numberof questions were prepared in a written form. The data obtained were analyzedthrough steps of selection, listing, translation, and interpretation of the formallinguistic meaning and cultural imagery of the MSC. The result of the data analysisis informally reported and verbally described.To analyze the data, the Cultural Linguistic Theory was applied andsupported by the structural and the dynamic theories. To know the chance and toinspire the study, a number of previous studies were reviewed. To easily understand,direct, and limit the discussion of the study, a number of basic concepts weredefined.Syntactically and semantically, there are four kinds of nominal markers(NMs of BM. NMs in the forms of personal pronouns (PP: hau ‘you SG’, hia/hi‘he/she’, meu ‘you-PLUR’, and ise ‘they’ mark proper nouns (PN as theSubject/Agent or Object/Patient in a clause bearing the meaning of subject or objectposition of a clause and not common nouns (CN. NMs in the forms of de/ di/ disemark the noun (CN/pronoun or PN as the possessor of the possessed noun in aclause bearing the meaning of possession. NMs in the forms of le/ li/ lise mark thenoun (CN/pronoun or PN as the agent diathesis of an action targeted to a noun asthe patient diathesis in a clause bearing the meaning of addition or the target/localityof an action. And NMs in the forms of ge/ gi/ gise mark the noun (CN/pronoun or

Simulating forensic casework scenarios in experimental studies: The generation of footwear marks in blood.

Science.gov (United States)

McElhone, Rachel L; Meakin, Georgina E; French, James C; Alexander, Tracy; Morgan, Ruth M

2016-07-01

A study was designed to investigate the effects of external variables, including blood type, flooring surface, footwear tread depth and blood dryness, on the appearance of blood-based footwear marks, with particular reference to simulating a specific casework scenario. Results showed that footwear marks left in human blood tended to be of greater quality than those in equine blood, highlighting a potential issue in applying data generated with equine blood to human bloodstains in casework. Footwear tread effects were also dependent on blood type, but the type of flooring surface did not affect the appearance of the mark. Under some conditions, as the blood dried, the amount of detail retained from footwear contact decreased. These results provide the beginnings of an empirical evidence base to allow a more accurate interpretation of blood-based footwear marks in forensic casework. When applied to a disputed bloodstain in a specific case, these results also demonstrate the importance of such experiments in narrowing the range of explanations possible in the interpretation of forensic evidence. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Preoperative Site Marking: Are We Adhering to Good Surgical Practice?

Science.gov (United States)

Bathla, Sonia; Chadwick, Michael; Nevins, Edward J; Seward, Joanna

2017-06-29

Wrong-site surgery is a never event and a serious, preventable patient safety incident. Within the United Kingdom, national guidance has been issued to minimize the risk of such events. The mandate includes preoperative marking of all surgical patients. This study aimed to quantify regional variation in practice within general surgery and opinions of the surgeons, to help guide the formulation and implementation of a regional general surgery preoperative marking protocol. A SurveyMonkey questionnaire was designed and distributed to 120 surgeons within the Mersey region, United Kingdom. This included all surgical trainees in Mersey (47 registrars, 56 core trainees), 15 consultants, and 2 surgical care practitioners. This sought to ascertain their routine practice and how they would choose to mark for 12 index procedures in general surgery, if mandated to do so. A total of 72 responses (60%) were obtained to the SurveyMonkey questionnaire. Only 26 (36.1%) said that they routinely marked all of their patients preoperatively. The operating surgeon marked the patient in 69% of responses, with the remainder delegating this task. Markings were visible after draping in only 55.6% of marked cases. Based on our findings, surgeons may not be adhering to "Good Surgical Practice"; practice is widely variable and surgeons are largely opposed and resistant to marking patients unless laterality is involved. We suggest that all surgeons need to be actively engaged in the design of local marking protocols to gain support, change practice, and reduce errors.

Modeling misidentification errors in capture-recapture studies using photographic identification of evolving marks

Science.gov (United States)

Yoshizaki, J.; Pollock, K.H.; Brownie, C.; Webster, R.A.

2009-01-01

Misidentification of animals is potentially important when naturally existing features (natural tags) are used to identify individual animals in a capture-recapture study. Photographic identification (photoID) typically uses photographic images of animals' naturally existing features as tags (photographic tags) and is subject to two main causes of identification errors: those related to quality of photographs (non-evolving natural tags) and those related to changes in natural marks (evolving natural tags). The conventional methods for analysis of capture-recapture data do not account for identification errors, and to do so requires a detailed understanding of the misidentification mechanism. Focusing on the situation where errors are due to evolving natural tags, we propose a misidentification mechanism and outline a framework for modeling the effect of misidentification in closed population studies. We introduce methods for estimating population size based on this model. Using a simulation study, we show that conventional estimators can seriously overestimate population size when errors due to misidentification are ignored, and that, in comparison, our new estimators have better properties except in cases with low capture probabilities (<0.2) or low misidentification rates (<2.5%). ?? 2009 by the Ecological Society of America.

Virtual tool mark generation for efficient striation analysis in forensic science

Energy Technology Data Exchange (ETDEWEB)

Ekstrand, Laura [Iowa State Univ., Ames, IA (United States)

2012-01-01

In 2009, a National Academy of Sciences report called for investigation into the scienti c basis behind tool mark comparisons (National Academy of Sciences, 2009). Answering this call, Chumbley et al. (2010) attempted to prove or disprove the hypothesis that tool marks are unique to a single tool. They developed a statistical algorithm that could, in most cases, discern matching and non-matching tool marks made at di erent angles by sequentially numbered screwdriver tips. Moreover, in the cases where the algorithm misinterpreted a pair of marks, an experienced forensics examiner could discern the correct outcome. While this research served to con rm the basic assumptions behind tool mark analysis, it also suggested that statistical analysis software could help to reduce the examiner's workload. This led to a new tool mark analysis approach, introduced in this thesis, that relies on 3D scans of screwdriver tip and marked plate surfaces at the micrometer scale from an optical microscope. These scans are carefully cleaned to remove noise from the data acquisition process and assigned a coordinate system that mathematically de nes angles and twists in a natural way. The marking process is then simulated by using a 3D graphics software package to impart rotations to the tip and take the projection of the tip's geometry in the direction of tool travel. The edge of this projection, retrieved from the 3D graphics software, becomes a virtual tool mark. Using this method, virtual marks are made at increments of 5 and compared to a scan of the evidence mark. The previously developed statistical package from Chumbley et al. (2010) performs the comparison, comparing the similarity of the geometry of both marks to the similarity that would occur due to random chance. The resulting statistical measure of the likelihood of the match informs the examiner of the angle of the best matching virtual mark, allowing the examiner to focus his/her mark analysis on a smaller range of angles

Selection of gender marked morphemes in speech production

NARCIS (Netherlands)

Schriefers, H.J.; Jescheniak, J.D.; Hantsch, A.

2005-01-01

N.O. Schiller and A. Caramazza (2003) and A. Costa, D. Kovacic, E. Fedorenko, and A. Caramazza (2003) have argued that the processing of freestanding gender-marked morphemes (e.g., determiners) and bound gender-marked morphemes (e.g., adjective suffixes) during syntactic encoding in speech

A method for studying knife tool marks on bone.

Science.gov (United States)

Shaw, Kai-Ping; Chung, Ju-Hui; Chung, Fang-Chun; Tseng, Bo-Yuan; Pan, Chih-Hsin; Yang, Kai-Ting; Yang, Chun-Pang

2011-07-01

The characteristics of knife tool marks retained on hard tissues can be used to outline the shape and angle of a knife. The purpose of this study was to describe such marks on bone tissues that had been chopped with knives. A chopping stage with a gravity accelerator and a fixed bone platform was designed to reconstruct the chopping action. A digital microscope was also used to measure the knife angle (θ) and retained V-shape tool mark angle (ψ) in a pig skull. The κ value (elasticity coefficient; θ/ψ) was derived and recorded after the knife angle (θ) and the accompanied velocity were compared with the proportional impulsive force of the knife and ψ on the bone. The constant impulsive force revealed a correlation between the V-shape tool mark angle (ψ) and the elasticity coefficient (κ). These results describe the tool marks--crucial in the medicolegal investigation--of a knife on hard tissues. © 2011 American Academy of Forensic Sciences.

Marking system for scintillation camera and computer, and its clinical application

Energy Technology Data Exchange (ETDEWEB)

Narabayashi, I [Kinki Univ., Higashi-Osaka, Osaka (Japan); Ito, K; Yoshida, S; Yamaguchi, H; Kahata, S

1976-03-01

In routine clinical studies, we have noted that in some cases anatomical marks have been transferred to scintigrams through the scintillation camera. It was thought that radioactive point sources could be used as anatomical marks. However, this method resulted in an ill-defined area of brightness. The marking equipment for the scintillation camera used in this study consisted of a linear potentiometer and a sine-cosine potentiometer. We designed a marking method for a data processing system using the marking equipment for a scintillation camera. The data processing system of a scintillation camera is composed of EDR-4000 (8K core memories), MT recorder, CRT display, and graphic display unit and it is connected by on-line to the scintillation camera. A marking program was made in order to record marking addresses on a processed image. Using this soft program and graphpen of the graphic display unit, we transferred marks to processed image by points and lines. Subtraction scintigraphy using /sup 198/Au-colloid and /sup 75/Se-selenomethionine was performed on cases of pancreas carcinoma. After marking addresses were recorded on a processed image by this marking method, the signals from the scintillation camera were fed into the input controller. Then these signals with marking points were transferred from the computer to the MT recorder. Subtraction scintigraphy by this system made it possible to examine each picture with /sup 198/Au-colloid of /sup 75/Se-selenomethionine at different times.

Using road markings as a continuous cue for speed choice.

Science.gov (United States)

Charlton, Samuel G; Starkey, Nicola J; Malhotra, Neha

2018-08-01

The potential for using road markings to indicate speed limits was investigated in a driving simulator over the course of two sessions. Two types of experimental road markings, an "Attentional" set designed to provide visually distinct cues to indicate speed limits of 60, 80 and 100 km/h, and a "Perceptual" set designed to also affect drivers' perception of speed, were compared to a standard undifferentiated set of markings. Participants (n = 20 per group) were assigned to one of four experimental groups (Attentional-Explicit, Attentional-Implicit, Perceptual-Explicit, Perceptual-Implicit) or a Control group (n = 22; standard road markings). The Explicit groups were instructed about the meaning of the road markings while those in the Implicit and Control groups did not receive any explanation. Participants drove five 10 km simulated roads containing three speed zones (60, 80 and 100 km/h) during the first session. The participants returned to the laboratory approximately 3 days later to drive five more trials including roads they had not seen before, a trial that included a secondary task, and a trial where speed signs were removed and only markings were present. The findings indicated that both types of road markings improved drivers' compliance with speed limits compared to the control group, but that explicit instruction as to the meaning of the markings was needed to realise their full benefit. Although previous research has indicated the benefit of road markings used as warnings to indicate speed reductions in advance of horizontal or vertical curves, the findings of the present experiment also suggest that systematically associating road markings with specific speed limits may be a useful way to improve speed limit compliance and increase speed homogeneity. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

Efficient computation of the inverse of gametic relationship matrix for a marked QTL

Directory of Open Access Journals (Sweden)

Iwaisaki Hiroaki

2006-04-01

Full Text Available Abstract Best linear unbiased prediction of genetic merits for a marked quantitative trait locus (QTL using mixed model methodology includes the inverse of conditional gametic relationship matrix (G-1 for a marked QTL. When accounting for inbreeding, the conditional gametic relationships between two parents of individuals for a marked QTL are necessary to build G-1 directly. Up to now, the tabular method and its adaptations have been used to compute these relationships. In the present paper, an indirect method was implemented at the gametic level to compute these few relationships. Simulation results showed that the indirect method can perform faster with significantly less storage requirements than adaptation of the tabular method. The efficiency of the indirect method was mainly due to the use of the sparseness of G-1. The indirect method can also be applied to construct an approximate G-1 for populations with incomplete marker data, providing approximate probabilities of descent for QTL alleles for individuals with incomplete marker data.

Variable features on Mars. VII - Dark filamentary markings on Mars

Science.gov (United States)

Veverka, J.

1976-01-01

The paper discusses the location, variability, and possible nature of well-developed patterns of dark filamentary markings in the Mariner 9 photographic records. Although not common on Mars, the markings are concentrated in at least two areas: Depressio Hellespontica and Cerberus/Trivium Charontis. In certain localities, strong winds are required to bring these markings into prominence. The dark filamentary markings seem to be true albedo features controlled by local topography, it being unlikely that they are free linear dunes. The distinctive criss-cross pattern seen in many of the pictures suggests that jointing provides the controlling topographic grid. At this stage it cannot be inferred whether the markings are erosional or depositional in character.

The Mark II Vertex Drift Chamber

International Nuclear Information System (INIS)

Alexander, J.P.; Baggs, R.; Fujino, D.

1989-03-01

We have completed constructing and begun operating the Mark II Drift Chamber Vertex Detector. The chamber, based on a modified jet cell design, achieves 30 μm spatial resolution and 2 gas mixtures. Special emphasis has been placed on controlling systematic errors including the use of novel construction techniques which permit accurate wire placement. Chamber performance has been studied with cosmic ray tracks collected with the chamber located both inside and outside the Mark II. Results on spatial resolution, average pulse shape, and some properties of CO 2 mixtures are presented. 10 refs., 12 figs., 1 tab

Acceptance and stress effects of aircraft obstruction markings of wind turbines

International Nuclear Information System (INIS)

Pohl, Johannes; Hübner, Gundula; Mohs, Anja

2012-01-01

A dominant resistance factor against wind power projects seems to be their visual impact on the landscape. In addition stress effects from aircraft obstruction markings are an emerging topic related to acceptance. As the height of wind turbines increases, so does the number of mandatory obstruction markings. Recently, obstruction markings have caused a growing number of complaints from residents. Whether obstruction markings indeed cause stress or even substantial annoyance remains an open question. To analyse the stress impact of obstruction markings, we used environmental and stress psychology methodologies. Residents (N=420) with direct sight of turbines at 13 wind farms participated in a questionnaire survey. Evidence of substantial annoyance caused by obstruction markings was not found. However, residents exposed to xenon lights reported more intense and multifaceted stress responses than exposed to LED or colour markings on blades. Moreover, xenon lights negatively affected the general acceptance of wind energy. Additionally, synchronised navigation lights were found to be less annoying than non-synchronised lights under certain weather conditions. Markings with light intensity adjustment proved to be advantageous. To reduce stress and increase social acceptance of wind power, xenon lights should be abandoned, navigation lights synchronised, and light intensity adjustment applied. - Research highlights: ► Wind turbine obstruction markings influence the social acceptance of wind energy. ► Residents exposed to xenon lights reported more intense stress responses than exposed to LED or colour markings. ► Synchronised lights were found to be less annoying under certain weather conditions. ► Markings with light intensity adjustment proved to be advantageous. ► Evidence of substantial annoyance caused by obstruction markings was not found.

Administering and Detecting Protein Marks on Arthropods for Dispersal Research.

Science.gov (United States)

Hagler, James R; Machtley, Scott A

2016-01-28

Monitoring arthropod movement is often required to better understand associated population dynamics, dispersal patterns, host plant preferences, and other ecological interactions. Arthropods are usually tracked in nature by tagging them with a unique mark and then re-collecting them over time and space to determine their dispersal capabilities. In addition to actual physical tags, such as colored dust or paint, various types of proteins have proven very effective for marking arthropods for ecological research. Proteins can be administered internally and/or externally. The proteins can then be detected on recaptured arthropods with a protein-specific enzyme-linked immunosorbent assay (ELISA). Here we describe protocols for externally and internally tagging arthropods with protein. Two simple experimental examples are demonstrated: (1) an internal protein mark introduced to an insect by providing a protein-enriched diet and (2) an external protein mark topically applied to an insect using a medical nebulizer. We then relate a step-by-step guide of the sandwich and indirect ELISA methods used to detect protein marks on the insects. In this demonstration, various aspects of the acquisition and detection of protein markers on arthropods for mark-release-recapture, mark-capture, and self-mark-capture types of research are discussed, along with the various ways that the immunomarking procedure has been adapted to suit a wide variety of research objectives.

Preoperative stoma site marking in the general surgery population.

Science.gov (United States)

Zimnicki, Katherine M

2013-01-01

Preoperative teaching and stoma site marking are supported by research and professional organizations as interventions that can reduce the incidence of problematic stomas and improve patient outcomes. This study investigated the translation of this research into practice in the acute care surgery population. A retrospective chart review using convenience sampling was conducted at a large urban hospital in the Midwestern United States. Thirty patients underwent a surgical procedure that resulted in the creation of a fecal ostomy over a 5-month period. Descriptive statistical analysis examined the reason for surgery, preoperative length of stay (LOS), the percentage of patients who received preoperative teaching and stoma marking and the relationship between preoperative LOS and the use of preoperative teaching and stoma marking. Twenty-one of 30 patients were admitted to hospital 24 hours or more before surgery. No participants were admitted urgently. Three (14%) of those admitted for more than 24 hours received preoperative marking or teaching. There was no significant relationship between preoperative LOS and preoperative teaching and stoma marking. The opportunity exists to promote successful adaptation in this surgical population through the implementation of the evidence-based interventions of preoperative teaching and stoma marking. Additional study is needed to determine barriers to their use as well as to develop effective implementation strategies.

Banner Marks of Ottoman Perıod at Giresun Museum

Directory of Open Access Journals (Sweden)

Gazanfer İLTAR

2015-12-01

Full Text Available The eleven banner marks among those that were brought together in 1926 to establish a museum at Tokat Gök Medrese (the Celestial Madrasa was sent to Giresun Museum in 1995 in order to be displayed together with other two thousand archaeological and ethnographic pieces. On the banner of one of these marks that was produced with brass hammering technique was written the date “1118/1706-1707”, which is indicated on its inventory record. Such marks that were decorated by using thuluth writing and vegetative motifs were made in the forms of round, drop, palmet and tulip. Generally, there exists a hilly part in the forms of palmet and drop on most of these marks which consist a handle and a body part. Additionally, there appear writings as “Allah, Muhammed, the words of Tawheed, Allah-Muhammed-Ali” on these marks. Today, the marks some of which are exhibited on the display cases and some of which are stored in museums are important in the sense of obtaining information about the art of metalworking in the period these marks were produced.

Identification markings for gemstones

International Nuclear Information System (INIS)

Dreschhoff, G.A.M.; Zeller, E.J.

1980-01-01

A method is described of providing permanent identification markings to gemstones such as diamond crystals by irradiating the cooled gemstone with protons in the desired pattern. The proton bombardment results in a reaction limited to a defined plane and converting the bombarded area of the plane into a different crystal lattice from that of the preirradiated stone. (author)

46 CFR 169.755 - Draft marks and draft indicating systems.

Science.gov (United States)

2010-10-01

... Section 169.755 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Vessel Control, Miscellaneous Systems, and Equipment Markings § 169.755 Draft marks and... projections of the marks onto a vertical plane are of uniform height equal to the vertical spacing between...

Survival and its predictors from age 75 to 85 in men and women belonging to cohorts with marked survival differences to age 75

DEFF Research Database (Denmark)

Heikkinen, E; Kauppinen, M; Schroll, M

2016-01-01

focusing on different domains of health, functional capacity, and physical and social activities. RESULTS: The proportion of survivors to age 75 was markedly smaller among the Finnish men and women than Danish or Swedish subjects. In the local population no marked differences in survival from age 75 to 85...... among three local Nordic populations using survival data on national cohorts as background information. METHODS: The data were derived from national registers and from samples of 75-year old living in Denmark, Sweden, and Finland. The subjects were invited to take part in interviews and examinations...... were observed between the groups of men, while women survived longer than men and longer in Göteborg than in Glostrup or Jyväskylä. Univariate models revealed 12 predictors of survival. In the multivariate models, the significant predictors among men related to physical fitness, whereas among women...

9 CFR 592.320 - Products that may bear the inspection mark.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Products that may bear the inspection... Marking Products § 592.320 Products that may bear the inspection mark. Products that are permitted to bear... products eligible to bear the inspection mark and may contain other edible ingredients. The official mark...

27 CFR 20.33 - Time of destruction of marks and brands.

Science.gov (United States)

2010-04-01

... marks and brands. 20.33 Section 20.33 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND... Administrative Provisions Marks and Brands § 20.33 Time of destruction of marks and brands. (a) Any person who... alcohol or specially denatured rum shall immediately destroy or obliterate the marks, brands, and labels...

Stress "Deafness" Reveals Absence of Lexical Marking of Stress or Tone in the Adult Grammar.

Directory of Open Access Journals (Sweden)

Hamed Rahmani

Full Text Available A Sequence Recall Task with disyllabic stimuli contrasting either for the location of prosodic prominence or for the medial consonant was administered to 150 subjects equally divided over five language groups. Scores showed a significant interaction between type of contrast and language group, such that groups did not differ on their performance on the consonant contrast, while two language groups, Dutch and Japanese, significantly outperformed the three other language groups (French, Indonesian and Persian on the prosodic contrast. Since only Dutch and Japanese words have unpredictable stress or accent locations, the results are interpreted to mean that stress "deafness" is a property of speakers of languages without lexical stress or tone markings, as opposed to the presence of stress or accent contrasts in phrasal (post-lexical constructions. Moreover, the degree of transparency between the locations of stress/tone and word boundaries did not appear to affect our results, despite earlier claims that this should have an effect. This finding is of significance for speech processing, language acquisition and phonological theory.

Ülar Mark: loome uut ja iga loomisega lammutame midagi / Ülar Mark ; intervjueerinud Mikk Salu

Index Scriptorium Estoniae

Mark, Ülar, 1968-

2010-01-01

Eesti Arhitektuurikeskuse juhatuse esimees, arhitekt Ülar Mark Tallinna arhitektuurist ja linna arengust, demokraatlikust linnaruumist. Pikemalt Solarise keskusest, vabadussambast, väikepoodide asemele suurte kaubanduskeskuste tulekust

Modelled seasonal influenza mortality shows marked differences in risk by age, sex, ethnicity and socioeconomic position in New Zealand.

Science.gov (United States)

Khieu, Trang Q T; Pierse, Nevil; Telfar-Barnard, Lucy Frances; Zhang, Jane; Huang, Q Sue; Baker, Michael G

2017-09-01

Influenza is responsible for a large number of deaths which can only be estimated using modelling methods. Such methods have rarely been applied to describe the major socio-demographic characteristics of this disease burden. We used quasi Poisson regression models with weekly counts of deaths and isolates of influenza A, B and respiratory syncytial virus for the period 1994 to 2008. The estimated average mortality rate was 13.5 per 100,000 people which was 1.8% of all deaths in New Zealand. Influenza mortality differed markedly by age, sex, ethnicity and socioeconomic position. Relatively vulnerable groups were males aged 65-79 years (Rate ratio (RR) = 1.9, 95% CI: 1.9, 1.9 compared with females), Māori (RR = 3.6, 95% CI: 3.6, 3.7 compared with European/Others aged 65-79 years), Pacific (RR = 2.4, 95% CI: 2.4, 2.4 compared with European/Others aged 65-79 years) and those living in the most deprived areas (RR = 1.8, 95% CI: 1.3, 2.4) for New Zealand Deprivation (NZDep) 9&10 (the most deprived) compared with NZDep 1&2 (the least deprived). These results support targeting influenza vaccination and other interventions to the most vulnerable groups, in particular Māori and Pacific people and men aged 65-79 years and those living in the most deprived areas. Copyright © 2017 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

Caffeine markedly sensitizes human mesothelioma cell lines to pemetrexed

Science.gov (United States)

Min, Sang Hee; Goldman, I. David; Zhao, Rongbao

2013-01-01

Pemetrexed is a new generation antifolate approved for the treatment of mesothelioma and non-small cell lung cancer. Caffeine is known to augment radiation or chemotherapeutic drug-induced cell killing. The current study addresses the impact of caffeine on the activity of pemetrexed in mesothelioma cell lines. Caffeine enhanced pemetrexed activity in all four mesothelioma cell lines tested (H2052, H2373, H28 and MSTO-211H). Caffeine sensitized H2052 cells in a dose- and schedule-dependent manner, and was associated with a markedly decreased clonogenic survival. Caffeine sensitization occurred only in cells subjected to pulse, but not continuous, exposure to pemetrexed. Similar pemetrexed sensitization was also observed with the clinically better tolerated caffeine analog, theobromine. Pemetrexed sensitization by caffeine was associated with an increase in pemetrexed-induced phosphorylation of ataxia-telangiectasia-mutated (ATM) and Chk1. These data indicate that caffeine and its analog, theobromine, may be a useful approach to enhance pemetrexed-based chemotherapy. PMID:17594092

7 CFR 319.37-10 - Marking and identity.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Marking and identity. 319.37-10 Section 319.37-10 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION..., and Other Plant Products 1,2 § 319.37-10 Marking and identity. (a) Any restricted article for...

Mediating effect of Facebook addiction on the relationship between subjective vitality and subjective happiness.

Science.gov (United States)

Uysal, Recep; Satici, Seydi Ahmet; Akin, Ahmet

2013-12-01

This study examined the mediating effects of Facebook addiction on the relationship between subjective vitality and subjective happiness. 297 university students (157 women, 140 men; M age = 20.1 yr., SD = 1.3) were administered the Facebook Addiction Scale, the Subjective Vitality Scale, and the Subjective Happiness Scale. Hierarchical regression analysis showed that Facebook addiction partially mediated the relationship between subjective vitality and subjective happiness.

Energy efficient sensor nodes placement using Territorial Predator Scent Marking Algorithm (TPSMA)

International Nuclear Information System (INIS)

Abidin, H Z; Din, N M

2013-01-01

The positions of sensor nodes in a Wireless Sensor Network (WSN) must be able to provide maximum coverage with a longer lifetime. This paper proposed a sensor node placement technique that utilizes a new biologically inspired optimization technique that imitates the behavior of territorial predators in marking their territories with their odors known as Territorial Predator Scent Marking Algorithm (TPSMA). The TPSMA deployed in this paper uses the maximum coverage ratio as the objective function. The performance of the proposed technique is then compared with other schemes in terms of uniformity and average energy consumption. Simulation results show that the WSN deployed with the proposed sensor node placement scheme consumes lower energy compared to the other two schemes and is expected to provide longer lifetime.

46 CFR 167.55-1 - Draft marks and draft indicating systems.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Draft marks and draft indicating systems. 167.55-1... NAUTICAL SCHOOL SHIPS Special Markings Required § 167.55-1 Draft marks and draft indicating systems. (a... aft to the location of the draft marks, due to a raked stem or cut away skeg, the draft must be...

Tense Marking in the English Narrative Retells of Dual Language Preschoolers.

Science.gov (United States)

Gusewski, Svenja; Rojas, Raúl

2017-07-26

This longitudinal study investigated the emergence of English tense marking in young (Spanish-English) dual language learners (DLLs) over 4 consecutive academic semesters, addressing the need for longitudinal data on typical acquisition trajectories of English in DLL preschoolers. Language sample analysis was conducted on 139 English narrative retells elicited from 39 preschool-age (Spanish-English) DLLs (range = 39-65 months). Growth curve models captured within- and between-individual change in tense-marking accuracy over time. Tense-marking accuracy was indexed by the finite verb morphology composite and by 2 specifically developed adaptations. Individual tense markers were systematically described in terms of overall accuracy and specific error patterns. Tense-marking accuracy exhibited significant growth over time for each composite. Initially, irregular past-tense accuracy was higher than regular past-tense accuracy; over time, however, regular past-tense marking outpaced accuracy on irregular verbs. These findings suggest that young DLLs can achieve high tense-marking accuracy assuming 2 years of immersive exposure to English. Monitoring the growth in tense-marking accuracy over time and considering productive tense-marking errors as partially correct more precisely captured the emergence of English tense marking in this population with highly variable expressive language skills. https://doi.org/10.23641/asha.5176942.

Multi-Disciplinary Peer-Mark Moderation of Group Work

Science.gov (United States)

Willmot, Peter; Pond, Keith

2012-01-01

Self and peer assessment offers benefits for enhancing student learning. Peer moderation provides a convenient solution for awarding individual marks in group assignments. This paper provides a significant review of peer-mark moderation, and describes an award winning, web-based tool that was developed in the UK and is now spreading across the…

Flow-induced vibration phenomenon in a Mark III TRIGA reactor

Energy Technology Data Exchange (ETDEWEB)

Lee, C K; Whittemore, W L; Kim, B S; Lee, J B; Blevins, R D; Burton, T E [Korea Atomic Energy Research Institute, Seoul (Korea, Republic of); General Atomic Company, San Diego, CA (United States)

1976-07-01

The Mark III TRIGA reactor with hexagonal fuel spacing is capable of operating at 2.0 MW. The Mark III at San Diego operated without core cooling problems or vibration at power levels up to 2.0 MW. All Mark III reactors have operated trouble-free up to 1.0 MW. The Mark III TRIGA in Korea was installed in 1972 and operated many months without trouble at 2.0 MW. During this period core changes including addition of new fuel were made. Eighteen months after startup, a coolant flow-induced vibration was observed for the first time at a power of 1.5 MW. A lengthy series of tests showed that it was not possible to establish a core configuration that permitted vibration-free operation for power levels in the range 1.5 - 2.0 MW. Observations during the tests confirmed that standing waves in the reactor tank water coupled the source within the core to the shield structure and surrounding building. Analysis of the data indicates strongly that the source of the vibration is the creation and collapse of bubbles with the core acting as a resonator. A substantially increased flow of coolant through the upper grid plate is expected to eliminate the vibration phenomenon and permit trouble-free operation at power up to 2.0 MW. In an attempt to seek a remedy, both GAC and KAERI have independently developed designs for upper grid plates. KAERI has constructed and installed an interim version of the standard grid plate which was calculated to provide 25% more coolant flow and mounted high so as to provide less restriction to flow around the upper fittings of the fuel elements. A substantial reduction in vibration was observed. No vibration was observed at any power up to 2.0 MW with cooling water at or below 20 C. A slight vibration at 1.8 MW occurred for higher cooling temperatures. The GAC grid plate design provides not only for increasing the flow area but also for streamlining the flow surfaces on the grid plate and possibly also on the top fittings of the fuel elements. It is

Flow-induced vibration phenomenon in a Mark III TRIGA reactor

International Nuclear Information System (INIS)

Lee, C.K.; Whittemore, W.L.; Kim, B.S.; Lee, J.B.; Blevins, R.D.; Burton, T.E.

1976-01-01

The Mark III TRIGA reactor with hexagonal fuel spacing is capable of operating at 2.0 MW. The Mark III at San Diego operated without core cooling problems or vibration at power levels up to 2.0 MW. All Mark III reactors have operated trouble-free up to 1.0 MW. The Mark III TRIGA in Korea was installed in 1972 and operated many months without trouble at 2.0 MW. During this period core changes including addition of new fuel were made. Eighteen months after startup, a coolant flow-induced vibration was observed for the first time at a power of 1.5 MW. A lengthy series of tests showed that it was not possible to establish a core configuration that permitted vibration-free operation for power levels in the range 1.5 - 2.0 MW. Observations during the tests confirmed that standing waves in the reactor tank water coupled the source within the core to the shield structure and surrounding building. Analysis of the data indicates strongly that the source of the vibration is the creation and collapse of bubbles with the core acting as a resonator. A substantially increased flow of coolant through the upper grid plate is expected to eliminate the vibration phenomenon and permit trouble-free operation at power up to 2.0 MW. In an attempt to seek a remedy, both GAC and KAERI have independently developed designs for upper grid plates. KAERI has constructed and installed an interim version of the standard grid plate which was calculated to provide 25% more coolant flow and mounted high so as to provide less restriction to flow around the upper fittings of the fuel elements. A substantial reduction in vibration was observed. No vibration was observed at any power up to 2.0 MW with cooling water at or below 20 C. A slight vibration at 1.8 MW occurred for higher cooling temperatures. The GAC grid plate design provides not only for increasing the flow area but also for streamlining the flow surfaces on the grid plate and possibly also on the top fittings of the fuel elements. It is

49 CFR 174.59 - Marking and placarding of rail cars.

Science.gov (United States)

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Marking and placarding of rail cars. 174.59... RAIL General Handling and Loading Requirements § 174.59 Marking and placarding of rail cars. No person may transport a rail car carrying hazardous materials unless it is marked and placarded as required by...

HYDROLOGIC AND FEATURE-BASED SURFACE ANALYSIS FOR TOOL MARK INVESTIGATION ON ARCHAEOLOGICAL FINDS

Directory of Open Access Journals (Sweden)

K. Kovács

2012-07-01

Full Text Available The improvement of detailed surface documentation methods provides unique tool mark-study opportunities in the field of archaeological researches. One of these data collection techniques is short-range laser scanning, which creates a digital copy of the object’s morphological characteristics from high-resolution datasets. The aim of our work was the accurate documentation of a Bronze Age sluice box from Mitterberg, Austria with a spatial resolution of 0.2 mm. Furthermore, the investigation of the entirely preserved tool marks on the surface of this archaeological find was also accomplished by these datasets. The methodology of this tool mark-study can be summarized in the following way: At first, a local hydrologic analysis has been applied to separate the various patterns of tools on the finds’ surface. As a result, the XYZ coordinates of the special points, which represent the edge lines of the sliding tool marks, were calculated by buffer operations in a GIS environment. During the second part of the workflow, these edge points were utilized to manually clip the triangle meshes of these patterns in reverse engineering software. Finally, circle features were generated and analysed to determine the different sections along these sliding tool marks. In conclusion, the movement of the hand tool could be reproduced by the spatial analysis of the created features, since the horizontal and vertical position of the defined circle centre points indicated the various phases of the movements. This research shows an exact workflow to determine the fine morphological structures on the surface of the archaeological find.

Scent marking behavior as an odorant communication in mice

Science.gov (United States)

Arakawa, Hiroyuki; Blanchard, D. Caroline; Arakawa, Keiko; Dunlap, Christopher; Blanchard, Robert J.

2008-01-01

In rodents, where chemical signals play a particularly important role in determining intraspecies interactions including social dominance and intersexual relationships, various studies have shown that behavior is sensitive to conspecific odor cues. Mice use urinary scent marks for communication with individual conspecifics in many social contexts. Urinary scent involves genetic information about individuals such as species, sex, and individual identity as well as metabolic information such as social dominance, and reproductive and health status, which are mediated by chemical proteins in scent marks including the major histocompatibility complex and the major urinary proteins. The odor of the predator which can be considered to be a threatening signal for the prey also modulate mouse behavior in which scent marking is suppressed in response to the cat odor exposure in mice. These odorant chemicals are detected and recognized through two olfactory bulbs, the role of which in detection of chemosignals with biological relevant appears to be differential, but partly overlapped. Mice deposit scent marks toward conspecifics to maintain their social relationships, and inhibit scent marking in a context where natural predator, cat odor is contained. This suppression of scent marking is long-lasting (for at least 7 days) and context-dependent, while the odorant signaling to conspecifics tends to appear frequently (over 24 hrs but less than 7 days intervals) depending on the familiarity of each signal-recipient. It has been discussed that scent marking is a communicative behavior associated with territoriality toward conspecifics, indicating that the social signaling within species are sensitive to predator odor cues in terms of vulnerability to predation risk. PMID:18565582

27 CFR 26.106 - Marking containers of beer.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Marking containers of beer... Liquors and Articles in Puerto Rico Beer § 26.106 Marking containers of beer. Containers of beer of Puerto... brewer; the serial number, capacity, and size of the container; the kind of beer; and the serial number...

27 CFR 26.97 - Marking containers of wine.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Marking containers of wine... Liquors and Articles in Puerto Rico Wine § 26.97 Marking containers of wine. Containers of wine of Puerto... winemaker, the serial number of the container, the kind and taxable grade of the wine, the gallon content...

Aksel Mark: kõik algaski Otsal / Enn Nõu

Index Scriptorium Estoniae

Nõu, Enn, 1933-

2012-01-01

Arvustus: Mark Beijer, Mai. Landkänning : Brevväxling mellan Anu och Aksel Mark under deras första år som flyktingar från Estland 1944-45. Stockholm : Bokverksta´n Förlag, 2008; Allt började på Otsa : minnen från min barndom och skoláren. Stockholm : Beijer Bok & Skog, 2011

Object marking in Swahili: Definiteness, specificity, or both ...

African Journals Online (AJOL)

This article examines the role of object marking in relation to definiteness and specificity in Swahili. Object marking in general has attracted the attention of many scholars in the field of Bantu linguistics due to the complex nature of object markers (OMs) and varying functions they fulfil in Bantu. Opinions differ on the role of ...

Fel d 1-derived synthetic peptide immuno-regulatory epitopes show a long-term treatment effect in cat allergic subjects.

Science.gov (United States)

Couroux, P; Patel, D; Armstrong, K; Larché, M; Hafner, R P

2015-05-01

Cat-PAD, the first in a new class of synthetic peptide immuno-regulatory epitopes (SPIREs), was shown to significantly improve rhinoconjunctivitis symptoms in subjects with cat allergy up to 1 year after the start of a short course of treatment. To evaluate the long-term effects of Cat-PAD on rhinoconjunctivitis symptoms following standardized allergen challenge 2 years after treatment. In a randomized, double-blind, placebo-controlled, parallel group study, subjects were exposed to cat allergen in an environmental exposure chamber (EEC) before and after treatment with two regimens of Cat-PAD (either eight doses of 3 nmol or four doses of 6 nmol) given intradermally over a 3-month period. In this follow-up study, changes from baseline in rhinoconjunctivitis symptoms were reassessed 2 years after the start of treatment. The primary endpoint showed a mean reduction in total rhinoconjunctivitis symptom scores of 3.85 units in the 4 × 6 nmol Cat-PAD group compared to placebo 2 years after the start of treatment (P = 0.13), and this difference was statistically significant in the secondary endpoint at the end of day 4 when the cumulative allergen challenge was greatest (P = 0.02). Consistent reductions in nasal symptoms of between 2 and 3 units were observed for 4 × 6 nmol Cat-PAD compared to placebo between the 2 and 3 h time points on days 1-4 of EEC challenge at 2 years (P Cat-PAD. This study is the first to provide evidence of a long-term therapeutic effect with this new class of SPIREs. © 2015 The Authors. Clinical & Experimental Allergy Published by John Wiley & Sons Ltd.

Mark Leonard : EL ei peakski olema suurvõim / Mark Leonard ; interv. Erkki Bahovski

Index Scriptorium Estoniae

Leonard, Mark

2008-01-01

Intervjuu Euroopa Välissuhete Nõukogu tegevdirektoriga, kes vastab küsimustele, mis puudutavad USA ja Euroopa suhteid, Euroopa Liidu välispoliitikat, Venemaa ja Euroopa Liidu suhteid pärast Gruusia konflikti. Ta peab murettekitavaks, et Venemaa üritab takistada euroopalike väärtuste levitamist oma naaberriikides. Vt. samas: Mark Leonard. Ilmunud ka Sirp : Diplomaatia 14. nov. nr. 11 lk. 13-14

Transgenerational isotopic marking of carp Cyprinus carpio, L. using a 86Sr /84Sr double spike

Science.gov (United States)

Zitek, Andreas; Cervicek, Magdalena; Irrgeher, Johanna; Horsky, Monika; Kletzl, Manfred; Weismann, Thomas; Prohaska, Thomas

2013-04-01

Transgenerational isotopic marking has been recognized recently as an effective tool for mass marking and tracking of individual fish to their original source. Compared to other conventional marking techniques, transgenerational marking offers several advantages. Most importantly, it is possible to mark all offspring of one individual female without the necessity of handling eggs or larval fish. Furthermore it is possible to vary the concentrations of individual isotopes to obtain specific marks for individual female fish. An enriched isotopic spike solution is usually applied to gravid female spawners by injection into the body cavity for transgenerational marking. The isotope is then incorporated into the central otolith region of the offspring which is known to be built up by maternally derived material. Within this study transgenerational marking of a typical cyprinid fish species, Cyprinus carpio, L., was tested using a 86Sr /84Sr double spike. Buffered solutions with different isotopic composition and concentrations were administered to 4 female individuals by intraperitoneal injection 5 days before spawning, while one female was injected a blank solution. After spawning, otoliths (Lapilli) from juvenile fish were sampled at the age of about 5 months at fish sizes between 3 and 4 cm and analyzed for their isotopic composition by LA-ICPMS applying cross sectional line scans. Central otolith regions of the progeny showed a shift in the natural isotope ratios for the administered isotopes. Deconvolution of the blank corrected measurement data of the Sr isotopes was done to trace back the original spike ratio. The different spike ratios could be well distinguished reflecting the original composition of the spike solution. This study proved that it is possible to create batch-specific unique transgenerational marks in otolith cores by varying the concentrations of two naturally occurring Sr isotopes. This method has high potential to reduce the marking effort for

TRANSITION METAL OXIDES AS MATERIALS FOR ADDITIVE LASER MARKING ON STAINLESS STEEL

Directory of Open Access Journals (Sweden)

Mihail Stoyanov Mihalev

2017-09-01

Full Text Available The product information plays an important role in the improvement of the manufacturing, allowing the tracking of the part through the full life cycle. Laser marking is one of the most versatile techniques for this purpose. In this paper, a modification of the powder bed selective laser melting for additive laser marking of stainless steel parts is presented. This modification is based on the use of only one transition metal oxide chemically bonded to the stainless steel substrate, without using any additional materials and cleaning substances. The resulting additive coatings, produced from initial MoO3 and WO3 powders, show strong adhesion, high hardness, long durability and a high optical contrast. For estimation of the chemical and structural properties, the Raman and X-Ray Diffraction (XRD spectroscopy have been implemented. A computer model of the process of the laser melting and re-solidification has been developed as well. A comparative analysis of the properties of both (MoO3 and WO3 additive coatings has been performed. An attempt for a qualitative explanation of the thermo-chemical phenomena during the marking process has been undertaken.

Pedestrian-driver communication and decision strategies at marked crossings.

Science.gov (United States)

Sucha, Matus; Dostal, Daniel; Risser, Ralf

2017-05-01

The aim of this work is to describe pedestrian-driver encounters, communication, and decision strategies at marked but unsignalised crossings in urban areas in the Czech Republic and the ways in which the parties involved experience and handle these encounters. A mixed-methods design was used, consisting of focus groups with pedestrians and drivers regarding their subjective views of the situations, on-site observations, camera recordings, speed measurements, the measurement of car and pedestrian densities, and brief on-site interviews with pedestrians. In close correspondence with the literature, our study revealed that the most relevant predictors of pedestrians' and drivers' behaviour at crossings were the densities of car traffic and pedestrian flows and car speed. The factors which influenced pedestrians' wait/go behaviour were: car speed, the distance of the car from the crossing, traffic density, whether there were cars approaching from both directions, various signs given by the driver (eye contact, waving a hand, flashing their lights), and the presence of other pedestrians. The factors influencing drivers' yield/go behaviour were: speed, traffic density, the number of pedestrians waiting to cross, and pedestrians being distracted. A great proportion of drivers (36%) failed to yield to pedestrians at marked crossings. The probability of conflict situations increased with cars travelling at a higher speed, higher traffic density, and pedestrians being distracted by a different activity while crossing. The findings of this study can add to the existing literature by helping to provide an understanding of the perception of encounter situations by the parties involved and the motives lying behind certain aspects of behaviour associated with these encounters. This seems necessary in order to develop suggestions for improvements. For instance, the infrastructure near pedestrian crossings should be designed in such a way as to take proper account of pedestrians

Amoralist rationalism? A response to Joel Marks: commentary on "Animal abolitionism meets moral abolitionism: cutting the Gordian knot of applied ethics" by Joel Marks.

Science.gov (United States)

Lederman, Zohar

2014-06-01

In a recent article, Joel Marks presents the amoralist argument against vivisection, or animal laboratory experimentation. He argues that ethical theories that seek to uncover some universal morality are in fact useless and unnecessary for ethical deliberations meant to determine what constitutes an appropriate action in a specific circumstance. I agree with Marks' conclusion. I too believe that vivisection is indefensible, both from a scientific and philosophical perspective. I also believe that we should become vegan (unfortunately, like the two philosophers mentioned by Marks, I too am still struggling to reduce my meat and dairy consumption). However, I am in the dark as to Marks' vision of normative deliberations in the spirit of amoralism and desirism.

Oxygen binding to nitric oxide marked hemoglobin

International Nuclear Information System (INIS)

Louro, S.R.W.; Ribeiro, P.C.; Bemski, G.

1979-04-01

Electron spin resonance spectra of organic phosphate free human hemoglobin marked with nitric oxide at the sixth coordination position of one of the four hemes allow to observe the transition from the tense (T) to the relaxed (R) conformation, as a function of parcial oxygen pressure. The spectra are composites of contributions from α sub(T), α sub(R) and β chains spectra, showing the presence of only two conformations: T and R. In the absence of organic phosphates NO binds to α and β chains with the same probability, but in the presence of phosphates NO combines preferentially with α chains. The dissociation of NO proceeds at least an order of magnitude faster in T than in R configuration. (author) [pt

Focal and optional ergative marking in Warrwa (Kimberley, Western Australia)

DEFF Research Database (Denmark)

McGregor, William

2006-01-01

Warrwa is a morphologically ergative language with three ergative markers, -na, -ma, and-nma. Intriguingly, while -ma is almost in complementary distribution with both -na and -nma, the latter pair are in "free variation'', and either can replace the other anywhere. When it is used, however, -nma...... accords prominence to an Agent (i.e. transitive subject), singling it out asboth unexpected and highly agentive; accordingly it can be considered to be a focal ergative marker.By contrast, -na is an ordinary ergative marker, with no pragmatic components to its meaning; the situation for -ma is uncertain....... The story is complicated further by the fact that ergative markers are occasionally omitted from Agent NPs. This ‘"optional'' ergative marking is not random: it defocusses the Agent, indicating that it is both expected and low in agentivity. Much of the paper is taken up by presentation of evidence for...

Revised Mark 22 coolant temperature coefficients

International Nuclear Information System (INIS)

Graves, W.E.

1987-01-01

Coolant temperature coefficients for the Mark 22 charge published previously are non-conservative because of the neglect of a significant mechanism which has a positive contribution to reactivity. Even after correcting for this effect, dynamic tests made on a Mark VIB charge in the early 60's suggest the results are still non-conservative. This memorandum takes both of these sources of information into account in making a best estimate of the prompt (coolant plus metal) temperature coefficient. Although no safety issues arise from this work (the overall temperature coefficient still strongly contributes to reactor stability), it is obviously desirable to use best estimates for prompt coefficients in limits and other calculations

22 CFR 226.91 - Marking.

Science.gov (United States)

2010-04-01

... Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ADMINISTRATION OF ASSISTANCE AWARDS TO U.S. NON-GOVERNMENTAL ORGANIZATIONS Miscellaneous § 226.91 Marking. (a) USAID policy is that all programs, projects, activities... support of the American people through the United States Agency for International Development (USAID). The...

Problems with ink skin markings for radiation field setups

International Nuclear Information System (INIS)

Endoh, Masaru; Saeki, Mituaki; Ishida, Yusei

1982-01-01

Ink skin markings are used in radiation therapy to aid in reproduction of treatment field setups or to indelibly outline field markings or tumors. We reported two cases of indelible ink skin for radiation field septa with minimal discomfort and dermatitis have been experienced for 6 months and above since end of radiotherapy. These indelible ink skin markings look like tattoo that will be big problems in the case of young female. We improved these problems by using of 10 percent silver nitrate instead of habitual skin ink. (author)

Maaväline lind Mark Raidpere / Fagira D. Morti

Index Scriptorium Estoniae

Fagira D. Morti, pseud., 1974-

2009-01-01

Soome Vabariigi president Tarja Halonen andis 28. veebruaril 2009. aastal Kumu Kunstimuuseumis videokunstnik Mark Raidperele üle Ars Fennica kunstipreemia. Meenutusi kunstniku EHI-s õppimise ajast, esimese näituse "Ilo" avamisest Vaal galeriis. Mark Raidpere loomingu mõistmisest

THE MARK I BUSINESS SYSTEM SIMULATION MODEL

Science.gov (United States)

of a large-scale business simulation model as a vehicle for doing research in management controls. The major results of the program were the...development of the Mark I business simulation model and the Simulation Package (SIMPAC). SIMPAC is a method and set of programs facilitating the construction...of large simulation models. The object of this document is to describe the Mark I Corporation model, state why parts of the business were modeled as they were, and indicate the research applications of the model. (Author)

The Things of Caesar: Mark-ing the Plural (Mk 12:13–17

Directory of Open Access Journals (Sweden)

Warren Carter

2014-09-01

Full Text Available This article observes the rarely-discussed phenomenon that the Marcan paying-the-tax scene refers to tax in the singular, whilst the concluding saying uses the plural ‘the things of Caesar and of God’. The article accounts for this phenomenon by means of developing traditions. The section under the heading ‘Mark’s scene and saying about taxes (12:13–17’ counters the common claim that scene and saying originated as a unit from the historical Jesus. It proposes that whilst the saying may have originated with Jesus, the scene as we have it did not. The section under the heading ‘Social memory, orality, and a multi-referential saying?’ suggests some contexts that the saying about the things of Caesar addressed pre-Mark. And under the section ‘Trauma and Mark’s scene’ it is argued that Mark created a unit comprising scene and saying to negotiate the ‘ trauma’ of the 66–70 war. The unit evaluates freshly-asserted Roman power as idolatrous and blasphemous whilst simultaneously authorising the continued involvement of Jesus-believers in imperial society.

Semi-automatic parking slot marking recognition for intelligent parking assist systems

Directory of Open Access Journals (Sweden)

Ho Gi Jung

2014-01-01

Full Text Available This paper proposes a semi-automatic parking slot marking-based target position designation method for parking assist systems in cases where the parking slot markings are of a rectangular type, and its efficient implementation for real-time operation. After the driver observes a rearview image captured by a rearward camera installed at the rear of the vehicle through a touchscreen-based human machine interface, a target parking position is designated by touching the inside of a parking slot. To ensure the proposed method operates in real-time in an embedded environment, access of the bird's-eye view image is made efficient: image-wise batch transformation is replaced with pixel-wise instantaneous transformation. The proposed method showed a 95.5% recognition rate in 378 test cases with 63 test images. Additionally, experiments confirmed that the pixel-wise instantaneous transformation reduced execution time by 92%.

Use of rhodamine B to mark the body and seminal fluid of male Aedes aegypti for mark-release-recapture experiments and estimating efficacy of sterile male releases.

Science.gov (United States)

Johnson, Brian J; Mitchell, Sara N; Paton, Christopher J; Stevenson, Jessica; Staunton, Kyran M; Snoad, Nigel; Beebe, Nigel; White, Bradley J; Ritchie, Scott A

2017-09-01

Recent interest in male-based sterile insect technique (SIT) and incompatible insect technique (IIT) to control Aedes aegypti and Aedes albopictus populations has revealed the need for an economical, rapid diagnostic tool for determining dispersion and mating success of sterilized males in the wild. Previous reports from other insects indicated rhodamine B, a thiol-reactive fluorescent dye, administered via sugar-feeding can be used to stain the body tissue and seminal fluid of insects. Here, we report on the adaptation of this technique for male Ae. aegypti to allow for rapid assessment of competitiveness (mating success) during field releases. Marking was achieved by feeding males on 0.1, 0.2, 0.4 or 0.8% rhodamine B (w/v) in 50% honey solutions during free flight. All concentrations produced >95% transfer to females and successful body marking after 4 days of feeding, with 0.4 and 0.8% solutions producing the longest-lasting body marking. Importantly, rhodamine B marking had no effect on male mating competitiveness and proof-of-principle field releases demonstrated successful transfer of marked seminal fluid to females under field conditions and recapture of marked males. These results reveal rhodamine B to be a potentially useful evaluation method for male-based SIT/IIT control strategies as well as a viable body marking technique for male-based mark-release-recapture experiments without the negative side-effects of traditional marking methods. As a standalone method for use in mating competitiveness assays, rhodamine B marking is less expensive than PCR (e.g. paternity analysis) and stable isotope semen labelling methods and less time-consuming than female fertility assays used to assess competitiveness of sterilised males.

Use of rhodamine B to mark the body and seminal fluid of male Aedes aegypti for mark-release-recapture experiments and estimating efficacy of sterile male releases.

Directory of Open Access Journals (Sweden)

Brian J Johnson

2017-09-01

Full Text Available Recent interest in male-based sterile insect technique (SIT and incompatible insect technique (IIT to control Aedes aegypti and Aedes albopictus populations has revealed the need for an economical, rapid diagnostic tool for determining dispersion and mating success of sterilized males in the wild. Previous reports from other insects indicated rhodamine B, a thiol-reactive fluorescent dye, administered via sugar-feeding can be used to stain the body tissue and seminal fluid of insects. Here, we report on the adaptation of this technique for male Ae. aegypti to allow for rapid assessment of competitiveness (mating success during field releases.Marking was achieved by feeding males on 0.1, 0.2, 0.4 or 0.8% rhodamine B (w/v in 50% honey solutions during free flight. All concentrations produced >95% transfer to females and successful body marking after 4 days of feeding, with 0.4 and 0.8% solutions producing the longest-lasting body marking. Importantly, rhodamine B marking had no effect on male mating competitiveness and proof-of-principle field releases demonstrated successful transfer of marked seminal fluid to females under field conditions and recapture of marked males.These results reveal rhodamine B to be a potentially useful evaluation method for male-based SIT/IIT control strategies as well as a viable body marking technique for male-based mark-release-recapture experiments without the negative side-effects of traditional marking methods. As a standalone method for use in mating competitiveness assays, rhodamine B marking is less expensive than PCR (e.g. paternity analysis and stable isotope semen labelling methods and less time-consuming than female fertility assays used to assess competitiveness of sterilised males.

Full-Scale Mark II CRT Program data report, 1

International Nuclear Information System (INIS)

Namatame, Ken; Kukita, Yutaka; Yamamoto, Nobuo; Shiba, Masayoshi

1979-12-01

The Full-Scale Mark II CRT (Containment Response Test) Program was initiated in April 1976 to provide a full-scale data basis for the evaluation of the pressure suppression pool hydrodynamic loads associated with a hypothetical LOCA in a BWR Mark II Containment. The test facility, completed in March 1979, is 1/18 in volume of a typical 1100 MWe Mark II, and has a wetwell which is a full-scale replica of one 20 0 -sector of that of the reference Mark II. The present report documents experimental data from TEST 0002, a medium size (100 mm) water blowdown test, performed by Hitachi Ltd. for JAERI as the second of the four shakedown tests. Test data is provided for the vessel depressurization, the pressure and temperature responses in the test containment, and especially for the chugging phenomena associated with low flux steam condensation in the pool. (author)

49 CFR 180.213 - Requalification markings.

Science.gov (United States)

2010-10-01

... eddy current examination combined with a visual inspection, the marking is as illustrated in paragraph..., securely affixed in a manner prescribed by the cylinder manufacturer, near the original manufacturer's...

Parts Quality Management: Direct Part Marking via Data Matrix Symbols for Mission Assurance

Science.gov (United States)

Moss, Chantrice

2013-01-01

A United States Government Accountability Office (GAO) review of twelve NASA programs found widespread parts quality problems contributing to significant cost overruns, schedule delays, and reduced system reliability. Direct part-marking with Data Matrix symbols could significantly improve the quality of inventory control and parts lifecycle management. This paper examines the feasibility of using 15 marking technologies for use in future NASA programs. A structural analysis is based on marked material type, operational environment (e.g., ground, suborbital, orbital), durability of marks, ease of operation, reliability, and affordability. A cost-benefits analysis considers marking technology (data plates, label printing, direct part marking) and marking types (two-dimensional machine-readable, human-readable). Previous NASA parts marking efforts and historical cost data are accounted for, including in-house vs. outsourced marking. Some marking methods are still under development. While this paper focuses on NASA programs, results may be applicable to a variety of industrial environments.

Parts Quality Management: Direct Part Marking of Data Matrix Symbol for Mission Assurance

Science.gov (United States)

Moss, Chantrice; Chakrabarti, Suman; Scott, David W.

2013-01-01

A United States Government Accountability Office (GAO) review of twelve NASA programs found widespread parts quality problems contributing to significant cost overruns, schedule delays, and reduced system reliability. Direct part marking with Data Matrix symbols could significantly improve the quality of inventory control and parts lifecycle management. This paper examines the feasibility of using direct part marking technologies for use in future NASA programs. A structural analysis is based on marked material type, operational environment (e.g., ground, suborbital, Low Earth Orbit), durability of marks, ease of operation, reliability, and affordability. A cost-benefits analysis considers marking technology (label printing, data plates, and direct part marking) and marking types (two-dimensional machine-readable, human-readable). Previous NASA parts marking efforts and historical cost data are accounted for, including inhouse vs. outsourced marking. Some marking methods are still under development. While this paper focuses on NASA programs, results may be applicable to a variety of industrial environments.

Liver enzymes in diabetic and non diabetic subjects with clinically diagnosed hepatitis

Directory of Open Access Journals (Sweden)

Bidhan Chandra Sarkar

2011-07-01

Full Text Available The occurrence of liver disease and raised liver enzymes is common in diabetic patients and the increasing level of enzymes indicates the severity of hepatic injury. Very few studies have addressed this issue in Bangladesh though Bangladeshi population is very much susceptible to diabetes. This study investigated a total of 1400 diabetic patients and 100 non diabetic individuals to compare the level of liver enzymes between diabetic and non-diabetic subjects. The comparisons were made among subjects who were referred to the department of Gastro-hepato-pancreatic diseases (GHPD of BIRDEM with the clinical diagnosis of chronic hepatitis and other gastro-intestinal disorders. The investigations included alanine aminotransferase (ALT, aspartate aminotransferase (AST, alkaline phosphatase (ALP and bilirubin levels. The subjects were categorized with and without hepatitis based on these investigations. The biochemical markers (ALT, AST, ALP, bilirubin did not differ significantly between non-diabetic male and female subjects. Neither the differences were significant between diabetic males and females though the diabetic patients had higher level of markers. In contrast, when compared between diabetic and non-diabetic subjects there were striking differences in either sex. Compared with the non-diabetic the diabetic subjects had significantly higher level of ALT (48.3 vs. 277.0, AST (42.0 vs. 213.0 and ALP (148 vs. 302 in males (p<0.005 for all. Similarly, these values were found significantly higher in diabetic females than their non-diabetic counterparts (p<0.01. For bilirubin, it was also found significant in males (p<0.001. The study revealed that the liver enzymes were found elevated in both diabetic and non-diabetic subjects who were referred with clinically diagnosed hepatitis. The enzymes were found markedly elevated among the diabetic than non diabetic patients, which indicate hepatic injury was more marked among the diabetic patients. Further

Microstructure of gross chill-mark defect in a glass-ceramic preform

International Nuclear Information System (INIS)

Spears, R.K.

1980-01-01

The microstructure of a vacuum tube glass-ceramic preform containing gross chill-marks on the top and bottom surfaces as well as on the sides was analyzed. The preform was ceramed in a graphite mold and examined using SEM. The glass-ceramic had an extremely dense and fine crystalline structure except where the chill-marks were located. In those areas of matrix glass following the chill-mark plane were evident. It is concluded that gross chill-marks will affect the microstructure by disrupting the chemistry or nucleating characteristics in such a way that a chill-mark regon would appear to be depleted of crystallites. Although the crystallites in this region are larger, the quantity is lower than in the base glass-ceramic. The affected area caused by the chill-mark left a band of matrix glass approximately 100 μ wide. It is believed that planar defects of this size will degrade the mechanical and permeation properties of the glass-ceramic

9 CFR 592.340 - Supervision of marking and packaging.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Supervision of marking and packaging... § 592.340 Supervision of marking and packaging. (a) Evidence of label approval. Inspection program... evidence that such official identification or packaging material bearing such official identification has...

76 FR 11432 - Coding of Design Marks in Registrations

Science.gov (United States)

2011-03-02

...] Coding of Design Marks in Registrations AGENCY: United States Patent and Trademark Office, Commerce... practice of coding newly registered trademarks that include a design element with design mark codes based... notice and request for comments at 75 FR 81587, proposing to discontinue a secondary system of coding...

Bite Mark Analysis in Foodstuffs and Inanimate Objects and the Underlying Proofs for Validity and Judicial Acceptance.

Science.gov (United States)

Rivera-Mendoza, Fernando; Martín-de-Las-Heras, Stella; Navarro-Cáceres, Pablo; Fonseca, Gabriel M

2018-03-01

Even though one of the first bite mark cases was Doyle v. State in 1954 (a bitten cheese case), the research has focused on bite marks inflicted in human skin. As published Papers, Case Reports, or Technical Notes can constitute precedents which are relied upon in making the legal arguments and a considerable amount of case law exists in this area, we present a systematic review on bite mark analysis in foodstuffs and inanimate objects and their underlying proofs for validity and judicial acceptance according to Daubert rulings. Results showed that there is vulnerability in these procedures, and it is essential to demand for focus scrutiny on the known error rates when such evidence is presented in trials. These kinds of bite marks are well documented; however, there has been little research in this field knowing that the protocols of analysis and comparison are the responsibility of the forensic odontologists. © 2017 American Academy of Forensic Sciences.

Reproductive function of monkeys subjected to chronic irradiation

International Nuclear Information System (INIS)

Artem'eva, N.S.; Kosichenko, L.P.; Andreeva, A.V.; Zvereva, G.A.

1976-01-01

Marked functional disorders have been detected in reproductive glands of eight female monkeys (as compared to twelve control animals) subjected to protracted (up to eight years) irradiation (cumulative doses 826-3282 R). Irradiated monkeys exhibited a drastically decreased reproductive capacity, early menopause and sterility. Irradiation of preadolescent animals inhibited, in most cases, the puberty processes and disturbed sex cycles. Structural disorders in sex glands, inhibition of the processes of maturation and ovulation of folloculi, death of the mass of germ cells, atypical vegetations of the integmentary epithelium, sclerosing and cystic degeneration of the glandular tissue have been revealed

Risk Aversion in Game Shows

DEFF Research Database (Denmark)

Andersen, Steffen; Harrison, Glenn W.; Lau, Morten I.

2008-01-01

We review the use of behavior from television game shows to infer risk attitudes. These shows provide evidence when contestants are making decisions over very large stakes, and in a replicated, structured way. Inferences are generally confounded by the subjective assessment of skill in some games......, and the dynamic nature of the task in most games. We consider the game shows Card Sharks, Jeopardy!, Lingo, and finally Deal Or No Deal. We provide a detailed case study of the analyses of Deal Or No Deal, since it is suitable for inference about risk attitudes and has attracted considerable attention....

Marked point process for modelling seismic activity (case study in Sumatra and Java)

Science.gov (United States)

Pratiwi, Hasih; Sulistya Rini, Lia; Wayan Mangku, I.

2018-05-01

Earthquake is a natural phenomenon that is random, irregular in space and time. Until now the forecast of earthquake occurrence at a location is still difficult to be estimated so that the development of earthquake forecast methodology is still carried out both from seismology aspect and stochastic aspect. To explain the random nature phenomena, both in space and time, a point process approach can be used. There are two types of point processes: temporal point process and spatial point process. The temporal point process relates to events observed over time as a sequence of time, whereas the spatial point process describes the location of objects in two or three dimensional spaces. The points on the point process can be labelled with additional information called marks. A marked point process can be considered as a pair (x, m) where x is the point of location and m is the mark attached to the point of that location. This study aims to model marked point process indexed by time on earthquake data in Sumatra Island and Java Island. This model can be used to analyse seismic activity through its intensity function by considering the history process up to time before t. Based on data obtained from U.S. Geological Survey from 1973 to 2017 with magnitude threshold 5, we obtained maximum likelihood estimate for parameters of the intensity function. The estimation of model parameters shows that the seismic activity in Sumatra Island is greater than Java Island.

9 CFR 316.12 - Marking of equine carcasses and parts thereof.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Marking of equine carcasses and parts... equine carcasses and parts thereof. (a) All inspected and passed equine carcasses and parts thereof... marking products in this part. (b) All equine carcasses and meat and other parts thereof shall be marked...

Mark Twain, Fenimore Cooper, and Batman.

Science.gov (United States)

Crick, Robert Alan

1992-01-01

Describes how Mark Twain's essay "Fenimore Cooper's Literary Offenses" helped students to get interested in writing and inspired them to write a similar essay critiquing the movie "Batman." Provides excerpts from students' essays. (PRA)

Linguistic gender marking and its international business ramifications

OpenAIRE

Estefania Santacreu-Vasut; Oded Shenkar; Amir Shoham

2014-01-01

We analyze the impact of language-based gender distinctions within languages’ grammatical structures on women’s corporate presence. Using four different data sets, we find that countries where the dominant language marks gender more intensely have significantly lower female participation on boards of directors and in senior management, as well as smaller female-led corporate teams. We also find that the gender marking of the language used in the headquarters’ home country impacts female prese...

Automatic Extraction of Road Markings from Mobile Laser Scanning Data

Science.gov (United States)

Ma, H.; Pei, Z.; Wei, Z.; Zhong, R.

2017-09-01

Road markings as critical feature in high-defination maps, which are Advanced Driver Assistance System (ADAS) and self-driving technology required, have important functions in providing guidance and information to moving cars. Mobile laser scanning (MLS) system is an effective way to obtain the 3D information of the road surface, including road markings, at highway speeds and at less than traditional survey costs. This paper presents a novel method to automatically extract road markings from MLS point clouds. Ground points are first filtered from raw input point clouds using neighborhood elevation consistency method. The basic assumption of the method is that the road surface is smooth. Points with small elevation-difference between neighborhood are considered to be ground points. Then ground points are partitioned into a set of profiles according to trajectory data. The intensity histogram of points in each profile is generated to find intensity jumps in certain threshold which inversely to laser distance. The separated points are used as seed points to region grow based on intensity so as to obtain road mark of integrity. We use the point cloud template-matching method to refine the road marking candidates via removing the noise clusters with low correlation coefficient. During experiment with a MLS point set of about 2 kilometres in a city center, our method provides a promising solution to the road markings extraction from MLS data.

Nõmme maja "Kergus" : Kerese tn., Tallinn / Ülar Mark, Kalle Komissarov

Index Scriptorium Estoniae

Mark, Ülar

1999-01-01

Kahekorruselise, tänavapoolse pika umbse seinaga eramu projekteeris Arhitektuuribüroo Mark & Tamm, arhitekt Ülar Mark, kaasautor Kalle Komissarov. Konstruktiivne osa: Randväli & Karema Inseneribüroo. Projekt 1997, hoone valmis 1999. Eramu tähenduse ümbermõtestamisest. 13 illustratsiooni: korruste plaanid, välisvaated, sisevaade.Mark & Tamm (arhitektibüroo)

27 CFR 26.207 - Destruction of marks and brands.

Science.gov (United States)

2010-04-01

... brands. 26.207 Section 26.207 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... Products Coming Into the United States From the Virgin Islands § 26.207 Destruction of marks and brands. The marks, brands, and serial numbers required by this part to be placed on barrels, casks, or similar...

27 CFR 26.41 - Destruction of marks and brands.

Science.gov (United States)

2010-04-01

... brands. 26.41 Section 26.41 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... Products Coming Into the United States From Puerto Rico § 26.41 Destruction of marks and brands. The marks, brands, and serial numbers required by this part to be placed on barrels, casks, or similar containers...

15 CFR 16.10 - The Department of Commerce Mark.

Science.gov (United States)

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false The Department of Commerce Mark. 16.10 Section 16.10 Commerce and Foreign Trade Office of the Secretary of Commerce PROCEDURES FOR A VOLUNTARY CONSUMER PRODUCT INFORMATION LABELING PROGRAM § 16.10 The Department of Commerce Mark. The Department of...

27 CFR 22.33 - Time of destruction of marks and brands.

Science.gov (United States)

2010-04-01

... marks and brands. 22.33 Section 22.33 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND... Provisions Destruction of Marks and Brands § 22.33 Time of destruction of marks and brands. (a) Any person..., brand, and labels required by this chapter to be placed on packages of tax-free alcohol. (b) A person...

H3S10ph broadly marks early-replicating domains in interphase ESCs and shows reciprocal antagonism with H3K9me2.

Science.gov (United States)

Chen, Carol C L; Goyal, Preeti; Karimi, Mohammad M; Abildgaard, Marie H; Kimura, Hiroshi; Lorincz, Matthew C

2018-01-01

Phosphorylation of histone H3 at serine 10 (H3S10ph) by Aurora kinases plays an important role in mitosis; however, H3S10ph also marks regulatory regions of inducible genes in interphase mammalian cells, implicating mitosis-independent functions. Using the fluorescent ubiquitin-mediated cell cycle indicator (FUCCI), we found that 30% of the genome in interphase mouse embryonic stem cells (ESCs) is marked with H3S10ph. H3S10ph broadly demarcates gene-rich regions in G1 and is positively correlated with domains of early DNA replication timing (RT) but negatively correlated with H3K9me2 and lamin-associated domains (LADs). Consistent with mitosis-independent kinase activity, this pattern was preserved in ESCs treated with Hesperadin, a potent inhibitor of Aurora B/C kinases. Disruption of H3S10ph by expression of nonphosphorylatable H3.3S10A results in ectopic spreading of H3K9me2 into adjacent euchromatic regions, mimicking the phenotype observed in Drosophila JIL-1 kinase mutants . Conversely, interphase H3S10ph domains expand in Ehmt1 (also known as Glp ) null ESCs, revealing that H3S10ph deposition is restricted by H3K9me2. Strikingly, spreading of H3S10ph at RT transition regions (TTRs) is accompanied by aberrant transcription initiation of genes co-oriented with the replication fork in Ehmt1 -/- and Ehmt2 -/- ESCs, indicating that establishment of repressive chromatin on the leading strand following DNA synthesis may depend upon these lysine methyltransferases. H3S10ph is also anti-correlated with H3K9me2 in interphase murine embryonic fibroblasts (MEFs) and is restricted to intragenic regions of actively transcribing genes by EHMT2. Taken together, these observations reveal that H3S10ph may play a general role in restricting the spreading of repressive chromatin in interphase mammalian cells. © 2018 Chen et al.; Published by Cold Spring Harbor Laboratory Press.

Marking behavior of the giant anteater Myrmecophaga tridactyla (Mammalia: Myrmecophagidae in Southern Brazil

Directory of Open Access Journals (Sweden)

Fernanda G. Braga

2010-02-01

Full Text Available This research presents novel data on tree marking by the giant anteater, a large Neotropical mammal threatened in the state of Paraná and other areas of Brazil, and nearly threatened worldwide. Field work was carried out in the municipality of Jaguariaíva, Paraná (Southern Brazil with the goal of evaluating the pine marking behavior of the giant anteater and ascertaining whether wildfires interfere with it. Anteater marks were searched for on the trunks of pine trees in stands as well as pine trees dispersed throughout the landscape. For each pine tree, the following features were recorded: height, diameter breast height (DBH, height of first branch, presence/absence of scratch marks, geographical location, substrate, and matrix. The total number of scratches, scratch directions, scratch length, and height of top mark were also recorded. The scratches were defined as horizontal or vertical. Tree scratching was directly observed in three instances. Ninety-one trees were measured in the study area. The differences between marked and non-marked pines were significant for DBH and height of first branch. All scratches were found on pines dispersed throughout the landscape. Trees with horizontal and vertical marks were significantly different in terms of DBH, first branch height, and top mark height. After a wildfire that affected part of the study area, 54% of the previously marked trees were marked anew. We suggest that the marking behavior is used for communication between conspecifics with overlapping home ranges, possibly during the mating season. Additionally, we advance the hypothesis that pine marking behavior becomes more frequent with increased population stress due to anthropic interference.

Determination of bench-mark elevations at Bethel Island and vicinity, Contra Costa and San Joaquin counties, California, 1987

Science.gov (United States)

Blodgett, J.C.; Ikehara, M.E.; McCaffrey, William F.

1988-01-01

Elevations of 49 bench marks in the southwestern part of the Sacramento-San Joaquin River Delta were determined during October and November 1987. A total of 58 miles of level lines were run in the vicinity of Bethel Island and the community of Discovery Bay. The datum of these surveys is based on a National Geodetic Survey bench mark T934 situated on bedrock 10.5 mi east of Mount Diablo and near Marsh Creek Reservoir. The accuracy of these levels, based on National Geodetic Survey standards, was of first, second, and third order, depending on the various segments surveyed. Several bench marks were noted as possibly being stable, but most show evidence of instability. (USGS)

An industry-scale mass marking technique for tracing farmed fish escapees.

Directory of Open Access Journals (Sweden)

Fletcher Warren-Myers

Full Text Available Farmed fish escape and enter the environment with subsequent effects on wild populations. Reducing escapes requires the ability to trace individuals back to the point of escape, so that escape causes can be identified and technical standards improved. Here, we tested if stable isotope otolith fingerprint marks delivered during routine vaccination could be an accurate, feasible and cost effective marking method, suitable for industrial-scale application. We tested seven stable isotopes, (134Ba, (135Ba, (136Ba, (137Ba, (86Sr, (87Sr and (26Mg, on farmed Atlantic salmon reared in freshwater, in experimental conditions designed to reflect commercial practice. Marking was 100% successful with individual Ba isotopes at concentrations as low as 0.001 µg. g-1 fish and for Sr isotopes at 1 µg. g-1 fish. Our results suggest that 63 unique fingerprint marks can be made at low cost using Ba (0.0002 - 0.02 $US per mark and Sr (0.46 - 0.82 $US per mark isotopes. Stable isotope fingerprinting during vaccination is feasible for commercial application if applied at a company level within the world's largest salmon producing nations. Introducing a mass marking scheme would enable tracing of escapees back to point of origin, which could drive greater compliance, better farm design and improved management practices to reduce escapes.

Clinical Effects of Fenfluramine in Ten Autistic Subjects. Brief Report.

Science.gov (United States)

Klykylo, William M.; And Others

1985-01-01

Use of the drug Fenfluramine, which reduces blood serotonin levels and possible problem behaviors, was evaluated. Nine of 10 Ss showed reduced serotonin; none showed significant differences on intelligence tests; and at least two Ss showed marked behavioral changes in less echolalia, perseveration, and motoric disturbance and more increases in…

46 CFR 160.054-6 - Marking.

Science.gov (United States)

2010-10-01

... “To Close, Press Together Full Length”. The marking may be applied to the container by the silk screen process, using a suitable ink or paint, or may be applied by other means shown to be acceptable. (b...

Mark's story as oral traditional literature: Rethinking the transmission ...

African Journals Online (AJOL)

The interpretation of Mark's gospel is inextricably linked to a conception of the gospel's genesis. By basing his argument on an aspect of the 'oral formulaic theory' the author of this paper argues that Mark's gospel can be seen as an example of oral traditional composition. The primary asset of this perspective is that it ...

The Mark, the Thing, and the Object: On What Commands Repetition in Freud and Lacan.

Science.gov (United States)

Van de Vijver, Gertrudis; Bazan, Ariane; Detandt, Sandrine

2017-01-01

In Logique du Fantasme , Lacan argues that the compulsion to repeat does not obey the same discharge logic as homeostatic processes. Repetition installs a realm that is categorically different from the one related to homeostatic pleasure seeking, a properly subjective one, one in which the mark "stands for," "takes the place of," what we have ventured to call "an event," and what only in the movement of return, in what Lacan calls a "thinking of repetition," confirms and ever reconfirms this point of no return, which is also a qualitative cut and a structural loss. The kind of "standing for" Lacan intends here with the concept of repetition is certainly not something like an image or a faithful description. No, what Lacan wishes to stress is that this mark is situated at another level, at another place, it is " entstellt ," and as such, it is punctually impinging upon the bodily dynamics without rendering the event, without having an external meta-point of view, but cutting across registers according to a logics that is not the homeostatic memory logics. This paper elaborates on this distinction on the basis of a confrontation with what Freud says about the pleasure principle and its beyond in Beyond the Pleasure Principle , and also takes inspiration from Freud's Project for a Scientific Psychology. We argue that Lacan's theory of enjoyment takes up and generalizes what Freud was after in Beyond the Pleasure Principle with the Wiederholungszwang , and pushes Freud's thoughts to a more articulated point: to the point where a subject is considered to speak only when it has allowed the other, through discourse, to have impacted and cut into his bodily pleasure dynamics.

AUTOMATIC EXTRACTION OF ROAD MARKINGS FROM MOBILE LASER SCANNING DATA

Directory of Open Access Journals (Sweden)

H. Ma

2017-09-01

Full Text Available Road markings as critical feature in high-defination maps, which are Advanced Driver Assistance System (ADAS and self-driving technology required, have important functions in providing guidance and information to moving cars. Mobile laser scanning (MLS system is an effective way to obtain the 3D information of the road surface, including road markings, at highway speeds and at less than traditional survey costs. This paper presents a novel method to automatically extract road markings from MLS point clouds. Ground points are first filtered from raw input point clouds using neighborhood elevation consistency method. The basic assumption of the method is that the road surface is smooth. Points with small elevation-difference between neighborhood are considered to be ground points. Then ground points are partitioned into a set of profiles according to trajectory data. The intensity histogram of points in each profile is generated to find intensity jumps in certain threshold which inversely to laser distance. The separated points are used as seed points to region grow based on intensity so as to obtain road mark of integrity. We use the point cloud template-matching method to refine the road marking candidates via removing the noise clusters with low correlation coefficient. During experiment with a MLS point set of about 2 kilometres in a city center, our method provides a promising solution to the road markings extraction from MLS data.

3D road marking reconstruction from street-level calibrated stereo pairs

Science.gov (United States)

Soheilian, Bahman; Paparoditis, Nicolas; Boldo, Didier

This paper presents an automatic approach to road marking reconstruction using stereo pairs acquired by a mobile mapping system in a dense urban area. Two types of road markings were studied: zebra crossings (crosswalks) and dashed lines. These two types of road markings consist of strips having known shape and size. These geometric specifications are used to constrain the recognition of strips. In both cases (i.e. zebra crossings and dashed lines), the reconstruction method consists of three main steps. The first step extracts edge points from the left and right images of a stereo pair and computes 3D linked edges using a matching process. The second step comprises a filtering process that uses the known geometric specifications of road marking objects. The goal is to preserve linked edges that can plausibly belong to road markings and to filter others out. The final step uses the remaining linked edges to fit a theoretical model to the data. The method developed has been used for processing a large number of images. Road markings are successfully and precisely reconstructed in dense urban areas under real traffic conditions.

Study of gunshot residues from Sintox® ammunition containing marking substances

Directory of Open Access Journals (Sweden)

Júlia Polovková

2015-12-01

Full Text Available Two types of factory marked Sintox® ammunition were investigated from the composition of gunshot residue particles (GSR and occurrence of marking substance points of view. The experiments were carried out with two cartridges of caliber 9 mm Luger (9 × 19 Parabellum of two producers (Ruag Ammotec, Switzerland and Men, Germany. The first cartridge (type Action 4, Ruag Ammotec contains gadolinium as a marking element, while the other cartridge (type PEP II, Men is marked with gallium in gunpowder. Scanning electron microscopy equipped with EDAX analyzer (SEM/EDX was used to detect and analyze the GSR particles in samples collected from the cartridges, barrels and shooter’s hands. Besides those, particles from the hit clothes placed at different shooting distances were collected and analyzed. The spreading of GSR cloud from the gun was observed using the high-speed camera. Results obtained clearly revealed that the way of ammunition production/construction and type of marking of ammunition can significantly influence the presence and detection reliability of marking elements in GSR. The detectability is affected also by the shooting distance.

Behavioural and magnetoencephalographic evidence for the interaction between semantic and episodic memory in healthy elderly subjects.

Science.gov (United States)

La Corte, Valentina; Dalla Barba, Gianfranco; Lemaréchal, Jean-Didier; Garnero, Line; George, Nathalie

2012-10-01

The relationship between episodic and semantic memory systems has long been debated. Some authors argue that episodic memory is contingent on semantic memory (Tulving 1984), while others postulate that both systems are independent since they can be selectively damaged (Squire 1987). The interaction between these memory systems is particularly important in the elderly, since the dissociation of episodic and semantic memory defects characterize different aging-related pathologies. Here, we investigated the interaction between semantic knowledge and episodic memory processes associated with faces in elderly subjects using an experimental paradigm where the semantic encoding of famous and unknown faces was compared to their episodic recognition. Results showed that the level of semantic awareness of items affected the recognition of those items in the episodic memory task. Event-related magnetic fields confirmed this interaction between episodic and semantic memory: ERFs related to the old/new effect during the episodic task were markedly different for famous and unknown faces. The old/new effect for famous faces involved sustained activities maximal over right temporal sensors, showing a spatio-temporal pattern partly similar to that found for famous versus unknown faces during the semantic task. By contrast, an old/new effect for unknown faces was observed on left parieto-occipital sensors. These findings suggest that the episodic memory for famous faces activated the retrieval of stored semantic information, whereas it was based on items' perceptual features for unknown faces. Overall, our results show that semantic information interfered markedly with episodic memory processes and suggested that the neural substrates of these two memory systems overlap.

14 CFR 221.200 - Content and explanation of abbreviations, reference marks and symbols.

Science.gov (United States)

2010-01-01

..., reference marks and symbols. 221.200 Section 221.200 Aeronautics and Space OFFICE OF THE SECRETARY... § 221.200 Content and explanation of abbreviations, reference marks and symbols. (a) Content. The format..., reference marks and symbols. Abbreviations, reference marks and symbols which are used in the tariff shall...

Haptic subjective vertical shows context dependence: task and vision play a role during dynamic tilt stimulation.

Science.gov (United States)

Wright, William Geoffrey; Glasauer, Stefan

2003-10-01

Perceiving one's vertical is an integral part of efficiently functioning in an environment physically polarized along that dimension. How one determines the direction of gravity is not a task left only to inertial sensors, such as the vestibular organs, rather as numerous studies have shown, this task is influenced visually and somatosensorily. In addition, there is evidence that higher order cognitive effects such as expectancies and context are critical in perception of the vertical. One's ability to integrate these various inputs during normal activity is not generally questioned, one's doubts being satisfied by observing a waiter navigating a crowded restaurant with a tray balanced on one hand, neither tripping or dropping an entree. But how these various sources are integrated is still debated. Most research focuses on subjective vertical perception used visual matching/alignment tasks, verbal reports, or saccadic eye movements as a dependent measure. Although a motor task involving a joystick or indicator to be aligned with gravity without visual feedback is used much less frequently, there is good evidence that individuals easily orient limbs to an external gravity-aligned coordinate axis while being statically tilted. By exposure to a dynamic situation, the central nervous system should be no more challenged by the task of determining the subjective vertical than during static conditions, because our spatial orientation systems were likely selected for just that. In addition, the sensitive calibration between visual and other sensory input also must have been key to its selection. This sensory interaction can be tested by changing the relation between the various sources. With the advent of virtual reality technology, a complex and "natural" visual stimulus is achievable and is easily manipulable. How one tests perception of verticality is also a pertinent question when researching spatial orientation systems. The system's performance may be better

The theological significance of the Isaiah citation in Mark 4:12 ...

African Journals Online (AJOL)

The well-known passage Mark 4:1–34 is no stranger to New Testament scientific scrutiny, not to even mention the hotly debated phrases in Mark 4:10–12. To avoid repetition, the aim with this article is to determine the extent of the impact the Isaiah 6:9–10 citation in Mark 4:12 might have had on the interpretation and ...

The Stingless Bee Melipona solani Deposits a Signature Mixture and Methyl Oleate to Mark Valuable Food Sources.

Science.gov (United States)

Alavez-Rosas, David; Malo, Edi A; Guzmán, Miguel A; Sánchez-Guillén, Daniel; Villanueva-Gutiérrez, Rogel; Cruz-López, Leopoldo

2017-10-01

Stingless bees foraging for food improve recruitment by depositing chemical cues on valuable food sites or pheromone marks on vegetation. Using gas chromatography/mass spectrometry and bioassays, we showed that Melipona solani foragers leave a mixture composed mostly of long chain hydrocarbons from their abdominal cuticle plus methyl oleate from the labial gland as a scent mark on rich food sites. The composition of hydrocarbons was highly variable among individuals and varied in proportions, depending on the body part. A wide ratio of compounds present in different body parts of the bees elicited electroantennogram responses from foragers and these responses were dose dependent. Generally, in bioassays, these bees prefer to visit previously visited feeders and feeders marked with extracts from any body part of conspecifics. The mean number of visits to a feeder was enhanced when synthetic methyl oleate was added. We propose that this could be a case of multi-source odor marking, in which hydrocarbons, found in large abundance, act as a signature mixture with attraction enhanced through deposition of methyl oleate, which may indicate a rich food source.

Better marking means cheaper pruning.

Science.gov (United States)

Kenneth R. Eversole

1953-01-01

Careful selection of trees to be pruned can make the difference between profit and loss on the pruning investment, especially in stands where no thinning is contemplated. Expert marking is required to make sure that the pruned trees will grow rapidly. The most important variable influencing the cost of clear wood produced by pruning is growth rate. For example, at 3...

Full-scale mark II CRT program data report, (5)

International Nuclear Information System (INIS)

Kukita, Yutaka; Namatame, Ken; Yamamoto, Nobuo; Takeshita, Isao; Shiba, Masayoshi

1980-03-01

The Full-Scale Mark II CRT (Containment Response Test) Program was initiated in 1977 to provide a data base for evaluation of the LOCA hydrodynamic loads for the Mark II pressure suppression system. The test facility is 1/18 in volume and has a wetwell which is a fullscale replica of one 20 0 -sector of that of a reference Mark II. This report documents test data obtained from TEST 2101, which is a medium size (74 mm) water break test performed on April 27, 1979. TEST 2101 was designed to roughly approximate an intermediate break accident in which so-called chugging phenomenon associated with low-flux steam condensation is anticipated to continue for a longer duration than in a large break accident. (author)

Mark I containment, short term program. Safety evaluation report

International Nuclear Information System (INIS)

1977-12-01

Presented is a Safety Evaluation Report (SER) prepared by the Office of Nuclear Reactor Regulation addressing the Short Term Program (STP) reassessment of the containment systems of operating Boiler Water Reactor (BWR) facilities with the Mark I containment system design. The information presented in this SER establishes the basis for the NRC staff's conclusion that licensed Mark I BWR facilities can continue to operate safely, without undue risk to the health and safety of the public, during an interim period of approximately two years while a methodical, comprehensive Long Term Program (LTP) is conducted. This SER also provides one of the basic foundations for the NRC staff review of the Mark I containment systems for facilities not yet licensed for operation

Ceremony marking Einstein Year

CERN Multimedia

2005-01-01

Sunday 13th November at 10:00amat Geneva's St. Peter's Cathedral To mark Einstein Year and the importance of the intercultural dialogue of which it forms a part, a religious service will take place on Sunday 13 November at 10 a.m. in St. Peter's Cathedral, to which CERN members and colleagues are warmly welcomed. Pastor Henry Babel, senior minister at the Cathedral, will speak on the theme: 'God in Einstein's Universe'. Diether Blechschmidt will convey a message on behalf of the scientific community.

The interplay of attention economics and computer-aided detection marks in screening mammography

Science.gov (United States)

Schwartz, Tayler M.; Sridharan, Radhika; Wei, Wei; Lukyanchenko, Olga; Geiser, William; Whitman, Gary J.; Haygood, Tamara Miner

2016-03-01

Introduction: According to attention economists, overabundant information leads to decreased attention for individual pieces of information. Computer-aided detection (CAD) alerts radiologists to findings potentially associated with breast cancer but is notorious for creating an abundance of false-positive marks. We suspected that increased CAD marks do not lengthen mammogram interpretation time, as radiologists will selectively disregard these marks when present in larger numbers. We explore the relevance of attention economics in mammography by examining how the number of CAD marks affects interpretation time. Methods: We performed a retrospective review of bilateral digital screening mammograms obtained between January 1, 2011 and February 28, 2014, using only weekend interpretations to decrease distractions and the likelihood of trainee participation. We stratified data according to reader and used ANOVA to assess the relationship between number of CAD marks and interpretation time. Results: Ten radiologists, with median experience after residency of 12.5 years (range 6 to 24,) interpreted 1849 mammograms. When accounting for number of images, Breast Imaging Reporting and Data System category, and breast density, increasing numbers of CAD marks was correlated with longer interpretation time only for the three radiologists with the fewest years of experience (median 7 years.) Conclusion: For the 7 most experienced readers, increasing CAD marks did not lengthen interpretation time. We surmise that as CAD marks increase, the attention given to individual marks decreases. Experienced radiologists may rapidly dismiss larger numbers of CAD marks as false-positive, having learned that devoting extra attention to such marks does not improve clinical detection.

Bench mark spectra for high-energy neutron dosimetry

International Nuclear Information System (INIS)

Dierckx, R.

1986-01-01

To monitor radiation damage experiments, activation detectors are commonly used. The precision of the results obtained by the multiple foil analysis is largely increased by the intercalibration in bench-mark spectra. This technique is already used in dosimetry measurements for fission reactors. To produce neutron spectra similar to fusion reactor and high-energy high-intensity neutron sources (d-Li or spallation), accelerators can be used. Some possible solutions as p-Be and d-D 2 O neutron sources, useful as bench-mark spectra are described. (author)

Geologic bench marks by terrestrial photography

Science.gov (United States)

Malde, Harold E.

1973-01-01

A photograph made with a level camera, if taken at a known height above a permanent mark on the ground, can be later repeated with exactness for measurement of changes in terrain. Such a photograph is one of several means for establishing a geologic bench mark and is especially useful for monitoring the subtle qualities of a landscape that are otherwise hard to map and describe, including the effects of man's use. Moreover, the geometry of such a photograph provides the same angular measurements between objects as can be made with a transit. A measurement of distance on a single photograph, however, requires control points. These can be surveyed at any convenient time, not necessarily when the initial photograph is made. Distances can also be determined by simple stereophotography from a base line of suitable length.

The neural basis of mark making: a functional MRI study of drawing.

Directory of Open Access Journals (Sweden)

Ye Yuan

Full Text Available Compared to most other forms of visually-guided motor activity, drawing is unique in that it "leaves a trail behind" in the form of the emanating image. We took advantage of an MRI-compatible drawing tablet in order to examine both the motor production and perceptual emanation of images. Subjects participated in a series of mark making tasks in which they were cued to draw geometric patterns on the tablet's surface. The critical comparison was between when visual feedback was displayed (image generation versus when it was not (no image generation. This contrast revealed an occipito-parietal stream involved in motion-based perception of the emerging image, including areas V5/MT+, LO, V3A, and the posterior part of the intraparietal sulcus. Interestingly, when subjects passively viewed animations of visual patterns emerging on the projected surface, all of the sensorimotor network involved in drawing was strongly activated, with the exception of the primary motor cortex. These results argue that the origin of the human capacity to draw and write involves not only motor skills for tool use but also motor-sensory links between drawing movements and the visual images that emanate from them in real time.

The Neural Basis of Mark Making: A Functional MRI Study of Drawing

Science.gov (United States)

Yuan, Ye; Brown, Steven

2014-01-01

Compared to most other forms of visually-guided motor activity, drawing is unique in that it “leaves a trail behind” in the form of the emanating image. We took advantage of an MRI-compatible drawing tablet in order to examine both the motor production and perceptual emanation of images. Subjects participated in a series of mark making tasks in which they were cued to draw geometric patterns on the tablet's surface. The critical comparison was between when visual feedback was displayed (image generation) versus when it was not (no image generation). This contrast revealed an occipito-parietal stream involved in motion-based perception of the emerging image, including areas V5/MT+, LO, V3A, and the posterior part of the intraparietal sulcus. Interestingly, when subjects passively viewed animations of visual patterns emerging on the projected surface, all of the sensorimotor network involved in drawing was strongly activated, with the exception of the primary motor cortex. These results argue that the origin of the human capacity to draw and write involves not only motor skills for tool use but also motor-sensory links between drawing movements and the visual images that emanate from them in real time. PMID:25271440

Scent-marking by coyotes, Canis latrans: the influence of social and ecological factors

Science.gov (United States)

Gese; Ruff

1997-11-01

We observed 49 coyotes, Canis latransfrom five resident packs for 2456 h and five transient coyotes for 51 h from January 1991 to June 1993 in the Lamar River Valley, Yellowstone National Park, Wyoming, U.S.A. During these observations we recorded 3042 urinations, 451 defecations, 446 ground scratches and 743 double-marks. The rate of scent-marking (via urination) was influenced by the social organization (resident versus transient) to which the coyote belonged, the social class (alpha, beta or pup) of the animal and the time of the year. Transient coyotes scent-marked at a lower rate than did members of a resident pack. Within the resident packs, alpha coyotes scent-marked at a higher rate than beta coyotes (adults and yearlings subordinant to alphas, but dominant over pups) and pups. Alpha coyotes increased their rate of marking during the breeding season; beta and pup coyotes performed scent-marks at a relatively constant rate throughout the year. There was no influence of social class or time of year on the rate of defecation. The rate of double-marking was highest among alpha coyotes with a peak during the breeding season. Alpha coyotes ground-scratched at a higher rate than did beta and pup coyotes. Alpha and beta coyotes scent-marked more than expected along the periphery of the territory compared to the interior; pups marked in the interior and edge in proportion to expected frequencies. Double-marking and ground-scratching were higher than expected along the periphery of the territory. The distribution of defecations was not different from expected along the edge versus the interior of the territory. Pack size did not influence the rate of scent-marking performed by individuals in the pack or by the alpha pair. We concluded that alpha coyotes were the primary members of the resident pack involved in scent-marking. The large coyote packs and the high rate of marking by the alpha pairs were parallel to the scent-marking behaviour displayed by wolves, C

Blocking oxytocin receptors inhibits vaginal marking to male odors in female Syrian hamsters.

Science.gov (United States)

Martinez, Luis A; Albers, H Elliott; Petrulis, Aras

2010-12-02

In Syrian hamsters (Mesocricetus auratus), precopulatory behaviors such as vaginal scent marking are essential for attracting a suitable mate. Vaginal marking is dependent on forebrain areas implicated in the neural regulation of reproductive behaviors in rodents, including the medial preoptic/anterior hypothalamus (MPOA-AH). Within MPOA-AH, the neuropeptide oxytocin (OT) acts to facilitate copulation (lordosis), as well as ultrasonic vocalizations towards males. It is not known, however, if OT in this area also facilitates vaginal marking. In the present study, a specific oxytocin receptor antagonist (OTA) was injected into MPOA-AH of intact female Syrian hamsters to determine if oxytocin receptor-dependent signaling is critical for the normal expression of vaginal marking elicited by male, female, and clean odors. OTA injections significantly inhibited vaginal marking in response to male odors compared with vehicle injections. There was no effect of OTA on marking in response to either female or clean odors. When injected into the bed nucleus of the stria terminalis (BNST), a nearby region to MPOA-AH, OTA was equally effective in decreasing marking. Finally, the effects of OTA appear to be specific to vaginal marking, as OTA injections in MPOA-AH or BNST did not alter general locomotor activity, flank marking, or social odor investigation. Considered together, these results suggest that OT in MPOA-AH and/or BNST normally facilitates male odor-induced vaginal marking, providing further evidence that OT generally supports prosocial interactions among conspecifics. Copyright © 2010 Elsevier Inc. All rights reserved.

Obesity is marked by distinct functional connectivity in brain networks involved in food reward and salience.

Science.gov (United States)

Wijngaarden, M A; Veer, I M; Rombouts, S A R B; van Buchem, M A; Willems van Dijk, K; Pijl, H; van der Grond, J

2015-01-01

We hypothesized that brain circuits involved in reward and salience respond differently to fasting in obese versus lean individuals. We compared functional connectivity networks related to food reward and saliency after an overnight fast (baseline) and after a prolonged fast of 48 h in lean versus obese subjects. We included 13 obese (2 males, 11 females, BMI 35.4 ± 1.2 kg/m(2), age 31 ± 3 years) and 11 lean subjects (2 males, 9 females, BMI 23.2 ± 0.5 kg/m(2), age 28 ± 3 years). Resting-state functional magnetic resonance imaging scans were made after an overnight fast (baseline) and after a prolonged 48 h fast. Functional connectivity of the amygdala, hypothalamus and posterior cingulate cortex (default-mode) networks was assessed using seed-based correlations. At baseline, we found a stronger connectivity between hypothalamus and left insula in the obese subjects. This effect diminished upon the prolonged fast. After prolonged fasting, connectivity of the hypothalamus with the dorsal anterior cingulate cortex (dACC) increased in lean subjects and decreased in obese subjects. Amygdala connectivity with the ventromedial prefrontal cortex was stronger in lean subjects at baseline, which did not change upon the prolonged fast. No differences in posterior cingulate cortex connectivity were observed. In conclusion, obesity is marked by alterations in functional connectivity networks involved in food reward and salience. Prolonged fasting differentially affected hypothalamic connections with the dACC and the insula between obese and lean subjects. Our data support the idea that food reward and nutrient deprivation are differently perceived and/or processed in obesity. Copyright © 2015 Elsevier B.V. All rights reserved.

Subjects with hip osteoarthritis show distinctive patterns of trunk movements during gait-a body-fixed-sensor based analysis

NARCIS (Netherlands)

Reininga, Inge H. F.; Stevens, Martin; Wagenmakers, Robert; Bulstra, Sjoerd K.; Groothoff, Johan W.; Zijlstra, Wiebren

2012-01-01

Background: Compensatory trunk movements during gait, such as a Duchenne limp, are observed frequently in subjects with osteoarthritis of the hip, yet angular trunk movements are seldom included in clinical gait assessments. Hence, the objective of this study was to quantify compensatory trunk

Do clinicians use more question marks?

NARCIS (Netherlands)

Zijlmans, Maeike; Otte, Willem M; Van't Klooster, Maryse A; van Diessen, Eric; Leijten, Frans Ss; Sander, Josemir W

2015-01-01

OBJECTIVE: To quantify the use of question marks in titles of published studies. DESIGN AND SETTING: Literature review. PARTICIPANTS: All Pubmed publications between 1 January 2013 and 31 December 2013 with an available abstract. Papers were classified as being clinical when the search terms clin*,

An acid phosphatase in the plasma membranes of human astrocytoma showing marked specificity toward phosphotyrosine protein.

Science.gov (United States)

Leis, J F; Kaplan, N O

1982-11-01

The plasma membrane from the human tumor astrocytoma contains an active acid phosphatase activity based on hydrolysis of p-nitrophenyl phosphate. Other acid phosphatase substrates--beta-glycerophosphate, O-phosphorylcholine, and 5'-AMP--are not hydrolyzed significantly. The phosphatase activity is tartrate insensitive and is stimulated by Triton X-100 and EDTA. Of the three known phosphoamino acids, only free O-phosphotyrosine is hydrolyzed by the membrane phosphatase activity. Other acid phosphatases tested from potato, wheat germ, milk, and bovine prostate did not show this degree of specificity. The plasma membrane activity also dephosphorylated phosphotyrosine histone at a much greater rate than did the other acid phosphatases. pH profiles for free O-phosphotyrosine and phosphotyrosine histone showed a shift toward physiological pH, indicating possible physiological significance. Phosphotyrosine histone dephosphorylation activity was nearly 10 times greater than that seen for phosphoserine histone dephosphorylation, and Km values were much lower for phosphotyrosine histone dephosphorylation (0.5 microM vs. 10 microM). Fluoride and zinc significantly inhibited phosphoserine histone dephosphorylation. Vanadate, on the other hand, was a potent inhibitor of phosphotyrosine histone dephosphorylation (50% inhibition at 0.5 microM) but not of phosphoserine histone. ATP stimulated phosphotyrosine histone dephosphorylation (160-250%) but inhibited phosphoserine histone dephosphorylation (95%). These results suggest the existence of a highly specific phosphotyrosine protein phosphatase activity associated with the plasma membrane of human astrocytoma.

Regionaalpoliitika ja arhitektuur / Ülar Mark

Index Scriptorium Estoniae

Mark, Ülar

1999-01-01

Kagu-Eesti Regionaalarengu Programmi raames Eesti Kunstiakadeemia arhitektuurikateedri IV kursuse eriala valikaines 1998/99 tehtud tööst "HyperMobiilne Reaalsus & Kagu Eesti" (juhendajad Ralf Tamm, Ülar Mark). Ühises töös osalesid Tartu Ülikooli geograafiatudengid (juhendaja Rein Ahas). 4 illustratsiooni

Marking behavior of Andean bears in an Ecuadorian cloud forest

NARCIS (Netherlands)

Filipczyková, Eva; Heitkonig, Ignas; Castellanos, Armando; Hantson, Wouter; Steyaert, Sam M.J.G.

2017-01-01

Very little is known about marking behavior of the endangered Andean bear (Tremarctos ornatus). Here, we present a first detailed description of Andean bear marking behavior obtained using camera traps. From November 2012 to April 2013, we inspected 16 bear trails in the Napo province of eastern

50 CFR 648.84 - Gear-marking requirements and gear restrictions.

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Gear-marking requirements and gear... Management Measures for the NE Multispecies and Monkfish Fisheries § 648.84 Gear-marking requirements and gear restrictions. (a) Bottom-tending fixed gear, including, but not limited to, gillnets and longlines...

7 CFR 906.340 - Container, pack, and container marking regulations.

Science.gov (United States)

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Container, pack, and container marking regulations... AGRICULTURE ORANGES AND GRAPEFRUIT GROWN IN LOWER RIO GRANDE VALLEY IN TEXAS Container and Pack Requirements § 906.340 Container, pack, and container marking regulations. (a) No handler shall handle any variety of...

9 CFR 381.204 - Marking of poultry products offered for entry; official import inspection marks and devices.

Science.gov (United States)

2010-01-01

... Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Marking of poultry products offered...

IP Traceback through modified Probabilistic Packet Marking algorithm using Chinese Remainder Theorem

Directory of Open Access Journals (Sweden)

Y. Bhavani

2015-06-01

Full Text Available Probabilistic Packet Marking algorithm suggests a methodology to identify all the participated routers of the attack path by probabilistically marking the packets. In this approach, these marked packets contain partial information regarding the routers of the attack path. At receiver, to get the complete information of every router, it requires more number of marked packets and hence more combinations and more false positives. To overcome this drawback we have presented a novel idea in finding the exact IP address of the routers in the attack path by applying Chinese Remainder Theorem. The result of our implementation reveals that our idea requires less number of marked packets and takes no time in constructing the attack path. The same idea is true even in the case of multiple attackers.

Thyroxine and triiodothyronine kinetics in aging subjects

International Nuclear Information System (INIS)

Degrossi, O.J.; Carneiro, L.; Scornavachi, J.C.; Cima, M.E.; Mollerach, F.E.; Almeida, C.A.; Casas, O.I. de; Diez, F.

1980-06-01

Age modifications on serum levels of thyrotropin hormone (TSH) thyroxine (T4) and Triiodothyronine (T3), as well the kinetics of T4 and T3 were studied. T4 serum values were found to be in the normal range. T3 rates showed a significant decrease as TSH showed a slight increase, which was only significantin patients over 70 year-old. Metabolic T4 turnover allowed to observe a slower T4 disappearance rate with dialy degradation values of 35,4 μg/day/m 2 +-14,1 (S.D.)as compared with those of the control subjects (49,0+-14,6): Distribution space was in the normal range. On the contrary, for T3 a sharp decrease in distribution space (31,1% body weight+-3,5; controls 58,8%+-7,6), a slight lengthening in disappearance rate and a marked shortening of the clearance (17,32 l/d+-6,20; controls 33,72+-8.55), of T3 extrathyroid pool (14,5 μg+-1,8; controls 45,7+-4.7) and of the daily degradation rate (4,3 μg/d/m 2 +-1,7; controls: 15,3+-2,6) were observed. These results conveys to considere a diminished thyroid hormones production and of an also diminished peripheric conversion of T4 to T3. It should be delucidated if there is a real inadequate thyroid hormones suply to the tissues or if there is only an adaptation, to lower demands due to a diminished functional mass [es

Learning to mark: a qualitative study of the experiences and concerns of medical markers

Directory of Open Access Journals (Sweden)

Cannings-John Rebecca

2006-04-01

Full Text Available Abstract Background Although there is published research on the methods markers use in marking various types of assessment, there is relatively little information on the processes markers use in approaching a marking exercise. This qualitative paper describes the preparation and experiences of general practice (GP teachers who undertake marking a written assessment in an undergraduate medical course. Methods Semi-structured interviews were conducted with seven of the 16 GP tutors on an undergraduate course. The purposive sample comprised two new markers, two who had marked for a couple of years and three experienced markers. Each respondent was interviewed twice, once following a formative assessment of a written case study, and again after a summative assessment. All interviews were audio-taped and analysed for emerging themes. A respondent validation exercise was conducted with all 16 GP tutors. Results Markers had internal concerns about their ability to mark fairly and made considerable efforts to calibrate their marking. They needed guidance and coaching when marking for the first time and adopted a variety of marking styles, reaching a decision through a number of routes. Dealing with pass/fail borderline scripts and the consequences of the mark on the student were particular concerns. Even experienced markers felt the need to calibrate their marks both internally and externally Conclusion Previous experience of marking appears to improve markers' confidence and is a factor in determining the role which markers adopt. Confidence can be improved by giving clear instructions, along with examples of marking. The authors propose that one method of providing this support and coaching could be by a process of peer review of a selection of papers prior to the main marking. New markers in particular would benefit from further guidance, however they are influenced by others early on in their marking career and course organisers should be mindful of

Stable isotope tracer marking of individual boll weevils

International Nuclear Information System (INIS)

James, W.D.; Showler, A.T.; Armstrong, J.S.; Westbrook, J.K.

2006-01-01

Stable isotope markers have been used to study animal nutrition for several decades and more recently to study the foraging and cultural habits of imported fire ants. In this work, we have extended that effort to evaluate the potential for marking boll weevils, Anthonomus grandis grandis Boheman (Coleoptera: Curculionidae), with the rare earth element samarium to aid in studies of insect invasion and pest eradication protocols. Neutron activation analysis (NAA) was performed on the marked boll weevils as well as plant material from the cotton squares on which the insects were fed. Samarium levels in non-dosed insects average about 20 ng/g or about 100 pg total element per insect. Our computed average determination limit was 36 pg samarium/weevil. The determination limit for cotton plant squares and leaves averaged 3.5 ng/g and 8.2 ng/g, respectively. These initial results indicate the NAA method is capable of identifying individual marked insects which have assimilated 1 ng of samarium, a ten-fold increase in content over average blank values. (author)

26 CFR 1.1296-1 - Mark to market election for marketable stock.

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Mark to market election for marketable stock. 1....1296-1 Mark to market election for marketable stock. (a) Definitions—(1) Eligible RIC. An eligible RIC... included in gross income by the company pursuant to such mark to market election with respect to such stock...

37 CFR 2.72 - Amendments to description or drawing of the mark.

Science.gov (United States)

2010-07-01

... drawing of the mark. 2.72 Section 2.72 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND....72 Amendments to description or drawing of the mark. (a) In an application based on use in commerce under section 1(a) of the Act, the applicant may amend the description or drawing of the mark only if...

Oxidative stress and inflammation in renal patients and healthy subjects.

Directory of Open Access Journals (Sweden)

Diana M Lee

Full Text Available The first goal of this study was to measure the oxidative stress (OS and relate it to lipoprotein variables in 35 renal patients before dialysis (CKD, 37 on hemodialysis (HD and 63 healthy subjects. The method for OS was based on the ratio of cholesteryl esters (CE containing C18/C16 fatty acids (R2 measured by gas chromatography (GC which is a simple, direct, rapid and reliable procedure. The second goal was to investigate and identify a triacylglycerol peak on GC, referred to as TG48 (48 represents the sum of the three fatty acids carbon chain lengths which was markedly increased in renal patients compared to healthy controls. We measured TG48 in patients and controls. Mass spectrometry (MS and MS twice in tandem were used to analyze the fatty acid composition of TG48. MS showed that TG48 was abundant in saturated fatty acids (SFAs that were known for their pro-inflammatory property. TG48 was significantly and inversely correlated with OS. Renal patients were characterized by higher OS and inflammation than healthy subjects. Inflammation correlated strongly with TG, VLDL-cholesterol, apolipoprotein (apo C-III and apoC-III bound to apoB-containing lipoproteins, but not with either total cholesterol or LDL-cholesterol.In conclusion, we have discovered a new inflammatory factor, TG48. It is characterized with TG rich in saturated fatty acids. Renal patients have increased TG48 than healthy controls.

The Mark, the Thing, and the Object: On What Commands Repetition in Freud and Lacan

Directory of Open Access Journals (Sweden)

Gertrudis Van de Vijver

2017-12-01

Full Text Available In Logique du Fantasme, Lacan argues that the compulsion to repeat does not obey the same discharge logic as homeostatic processes. Repetition installs a realm that is categorically different from the one related to homeostatic pleasure seeking, a properly subjective one, one in which the mark “stands for,” “takes the place of,” what we have ventured to call “an event,” and what only in the movement of return, in what Lacan calls a “thinking of repetition,” confirms and ever reconfirms this point of no return, which is also a qualitative cut and a structural loss. The kind of “standing for” Lacan intends here with the concept of repetition is certainly not something like an image or a faithful description. No, what Lacan wishes to stress is that this mark is situated at another level, at another place, it is “entstellt,” and as such, it is punctually impinging upon the bodily dynamics without rendering the event, without having an external meta-point of view, but cutting across registers according to a logics that is not the homeostatic memory logics. This paper elaborates on this distinction on the basis of a confrontation with what Freud says about the pleasure principle and its beyond in Beyond the Pleasure Principle, and also takes inspiration from Freud’s Project for a Scientific Psychology. We argue that Lacan’s theory of enjoyment takes up and generalizes what Freud was after in Beyond the Pleasure Principle with the Wiederholungszwang, and pushes Freud’s thoughts to a more articulated point: to the point where a subject is considered to speak only when it has allowed the other, through discourse, to have impacted and cut into his bodily pleasure dynamics.

Survival of radio-marked mallard ducklings in northeastern California

Science.gov (United States)

Mauser, D.M.; Jarvis, R.L.; Gilmer, D.S.

1994-01-01

Estimates of duckling survival are necessary to accurately assess recruitment of mallards (Anas platyrhynchos), yet few reliable estimates exist. During 1988-90, we estimated survival rates for 127 radio-marked mallard ducklings from 64 broods on Lower Klamath National Wildlife Refuge, California. In 1988, we restricted the survival estimate to the first 10 days post-hatch (S = 0.18, SE = 0.07). Survival from hatching to 50 days was 0.37 (SE = 0.09) in 1989 and 0.34 (SE = 0.07) in 1990. Total brood loss differed among years (P < 0.05); 81.2% in 1988 (n = 16), 36.8% in 1989 (n = 19), and 37.5% in 1990 (n = 24). Ninety-three percent of mortality occurred during the first 10 days of life. We detected no differences in the proportion of radio-marked ducklings fledged from early-hatched versus late-hatched nests (P = 0.74). During 1989-90, 16 females appeared to lose their entire brood; however, 3 radio-marked ducklings from 2 of these broods were fledged by other brood hens. Of 29 radio-marked ducklings that reached 44 days of life, 6 (20.7%) joined other broods. Habitat enhancement is the key to improving duckling survival because the large number of predator species that consume ducklings makes predator control difficult.

[Evaluation of the lifetime of nail markings during polio vaccinations in Chad].

Science.gov (United States)

Quoc Cuong, Huong; Schlumberger, Martin; Garba Tchang, Salomon; Ould Cheikh, Dah; Savès, Marianne; Mallah, Barah; Demtilo Attilo, Jacques; Ngangro Mosurel, Ndeikoundam; Gamatié, Youssouf

2010-01-01

SID (Supplemental Immunization Days) is a special strategy intended to accelerate eradication of poliomyelitis in countries where it is still endemic (India, Afghanistan, and Pakistan in Asia, and Nigeria in Africa). This strategy is also applied in Nigeria's neighbours (Cameroon, Chad, Niger and Benin). Since the poliomyelitis virus was imported from Nigeria in 2001, Chad has reported cases of poliomyelitis every year. After 30 SIDs in Chad and the inaccurate or false attribution of side-effects to polio vaccines, some groups persistently refuse polio vaccination. To ascertain the true coverage of SID, the Ministry of Health and several partners (WHO, UNICEF and Rotary) conduct external coverage evaluations, to identify the under-vaccinated areas where population may be refusing immunization. The nails of the children receiving vaccinations are marked with indelible ink and those markings are the best indicator of the area's actual SID coverage. When coverage investigators arrive and propose vaccination to all children not immunized during SID, mothers who wish to refuse vaccination may claim that the children's markings disappeared after a few days, due to bathing. WHO experts have found that markings applied to their own nails with the WHO-recommended markers persist a few weeks, but others suggested that the markings may disappear much faster among children living in a traditional tropical environment. Until now, the lifetime of these markings has not been tested among children in Africa. To determine the lifetime of the fingernail markings after SID and factors that influence this lifetime in children young than 5 years old in Chad. This prospective cohort study of 200 children (aged 0 to 59 months) took place from March to May 2009 in Milezi, a health zone north of Ndjamena, the capital of Chad, in central Africa. These children received nail markings on their left little finger with an indelible marker pen provided by WHO. The finger was monitored for 35

15 CFR 1150.3 - Approved markings.

Science.gov (United States)

2010-01-01

... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Approved markings. 1150.3 Section 1150.3 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued... permanently affixed to the exterior surface of the barrel, covering the circumference of the barrel from the...

Pattern of neural responses to verbal fluency shows diagnostic specificity for schizophrenia and bipolar disorder

Directory of Open Access Journals (Sweden)

Walshe Muriel

2011-01-01

Full Text Available Abstract Background Impairments in executive function and language processing are characteristic of both schizophrenia and bipolar disorder. Their functional neuroanatomy demonstrate features that are shared as well as specific to each disorder. Determining the distinct pattern of neural responses in schizophrenia and bipolar disorder may provide biomarkers for their diagnoses. Methods 104 participants underwent functional magnetic resonance imaging (fMRI scans while performing a phonological verbal fluency task. Subjects were 32 patients with schizophrenia in remission, 32 patients with bipolar disorder in an euthymic state, and 40 healthy volunteers. Neural responses to verbal fluency were examined in each group, and the diagnostic potential of the pattern of the neural responses was assessed with machine learning analysis. Results During the verbal fluency task, both patient groups showed increased activation in the anterior cingulate, left dorsolateral prefrontal cortex and right putamen as compared to healthy controls, as well as reduced deactivation of precuneus and posterior cingulate. The magnitude of activation was greatest in patients with schizophrenia, followed by patients with bipolar disorder and then healthy individuals. Additional recruitment in the right inferior frontal and right dorsolateral prefrontal cortices was observed in schizophrenia relative to both bipolar disorder and healthy subjects. The pattern of neural responses correctly identified individual patients with schizophrenia with an accuracy of 92%, and those with bipolar disorder with an accuracy of 79% in which mis-classification was typically of bipolar subjects as healthy controls. Conclusions In summary, both schizophrenia and bipolar disorder are associated with altered function in prefrontal, striatal and default mode networks, but the magnitude of this dysfunction is particularly marked in schizophrenia. The pattern of response to verbal fluency is highly

Implementing New Methods of Laser Marking of Items in the Nuclear Material Control and Accountability System at SSC RF-IPPE: An Automated Laser Marking System

International Nuclear Information System (INIS)

Regoushevsky, V.I.; Tambovtsev, S.D.; Dvukhsherstnov, V.G.; Efimenko, V.F.; Ilyantsev, A.I.; Russ, G.P. III

2009-01-01

For over ten years SSC RF-IPPE, together with the US DOE National Laboratories, has been working on implementing automated control and accountability methods for nuclear materials and other items. Initial efforts to use adhesive bar codes or ones printed (painted) onto metal revealed that these methods were inconvenient and lacked durability under operational conditions. For NM disk applications in critical stands, there is the additional requirement that labels not affect the neutron characteristics of the critical assembly. This is particularly true for the many stainless-steel clad disks containing highly enriched uranium (HEU) and plutonium that are used at SSC RF-IPPE for modeling nuclear power reactors. In search of an alternate method for labeling these disks, we tested several technological options, including laser marking and two-dimensional codes. As a result, the method of laser coloring was chosen in combination with Data Matrix ECC200 symbology. To implement laser marking procedures for the HEU disks and meet all the nuclear material (NM) handling standards and rules, IPPE staff, with U.S. technical and financial support, implemented an automated laser marking system; there are also specially developed procedures for NM movements during laser marking. For the laser marking station, a Zenith 10F system by Telesis Technologies (10 watt Ytterbium Fiber Laser and Merlin software) is used. The presentation includes a flowchart for the automated system and a list of specially developed procedures with comments. Among other things, approaches are discussed for human-factor considerations. To date, markings have been applied to numerous steel-clad HEU disks, and the work continues. In the future this method is expected to be applied to other MC and A items.

Ecosecent:: Essence, Subject and Structure

Directory of Open Access Journals (Sweden)

Kozachenko Hanna V.

2014-02-01

Full Text Available The article shows that due to multi-laterality the knowledge about security is distributed by various branches, one of which is ecosestate, within which conditions of secure functioning of socio-economic systems and methods of their provision are studied. It shows the essence of ecosecent as a component of the “state – region (branch – subject of economic activity” ecosestate vertical – a set of knowledge about economic security of subjects of economic activity. It considers reasons that cause establishment of ecosecent: practical needs and a necessity to reconsider basic concepts of the essence, limits and factors of economy. It formulates the subject of ecosecent. It considers the status of the “economic security of the subject of economic activity” notion as its state, described with a set of parameters or characteristic features as characteristics of the subject of economic activity as a condition of its activity and as a set of actions that allow ensuring or preservation of the state of security, in other words, protection of the subject of economic activity. It presents general approaches to structuring of ecosecent by activity, functional and branch features.

[Marked hemosiderosis in myelodysplastic syndrome].

Science.gov (United States)

Klinz, C

1999-01-29

A 68-year-old man was admitted because of symptoms of lumbar pain. He was known to have chronic anemia with ring sideroblasts and diabetes melitus and to be in heart failure. Three months before he had been given 7 units of red cell concentrate. On admission the outstanding features were brown discoloration of the skin, absent body hair, tachycardia, hepatomegaly and small testicles. He had a normocytic anemia, hyperglycemia and raised transaminases, hypogonadism and vitamin D3 deficiency. The serum levels of iron, transferrin saturation and feritin were markedly elevated. Liver iron content/g dried liver was 4.2 g (by biomagnetometer). Radiology of the lumbar vertebrae showed osteoporosis and sonography confirmed hepatomegaly. The known myelodysplastic syndrome (MDS) had fed to secondary hemosiderosis with heart failure, liver involvement, diabetes mellitus, hypogonadism and osteoporosis. Symptomatic treatment was unsuccessfully complemented by desferoxamine (up to 4 g/12 h) to release iron. But very good iron excretion was then achieved with deferiprone (3 x 1 g/d). The patient later died of the sequelae of hemosiderosis. Even when they have not required transfusions, patients with long-standing MDS should be examined regularly for the possible development of secondary hemosiderosis so that iron-chelating agents can be administered as needed.

Skype'i kaasasutajad investeerivad MarkIT-isse

Index Scriptorium Estoniae

2007-01-01

Nelja eestlasest Skype'i kaasasutaja loodud Ambient Sound Investments (ASI) investeerib 2 miljonit eurot, et aidata kaasa MarkIT e-hankekeskkonna arendamisele ning ettevõtte laienemisele viide Kesk- ja Ida-Euroopa riiki

Trade Mark Coexistence Agreements: What is all the (lack of) fuss about?

DEFF Research Database (Denmark)

Elsmore, Matthew J.

2008-01-01

time and space is allocated to trade mark coexistence agreements. Despite a shortage of authoritative rulings, it is not immediately clear why, especially as they may be having a profound impact on the use of product markers. Coexistence agreements commonly exist between parties with at least similar...... trade marks who decide to formally coexist, often in the wake of legal skirmishes. In the busy European market, where Community-wide protection is available, an up-front contract may be an attractive way to avoid trade mark conflict. When these contracts work, trade mark law is effectively pre...

Selection on Coding and Regulatory Variation Maintains Individuality in Major Urinary Protein Scent Marks in Wild Mice.

Directory of Open Access Journals (Sweden)

Michael J Sheehan

2016-03-01

Full Text Available Recognition of individuals by scent is widespread across animal taxa. Though animals can often discriminate chemical blends based on many compounds, recent work shows that specific protein pheromones are necessary and sufficient for individual recognition via scent marks in mice. The genetic nature of individuality in scent marks (e.g. coding versus regulatory variation and the evolutionary processes that maintain diversity are poorly understood. The individual signatures in scent marks of house mice are the protein products of a group of highly similar paralogs in the major urinary protein (Mup gene family. Using the offspring of wild-caught mice, we examine individuality in the major urinary protein (MUP scent marks at the DNA, RNA and protein levels. We show that individuality arises through a combination of variation at amino acid coding sites and differential transcription of central Mup genes across individuals, and we identify eSNPs in promoters. There is no evidence of post-transcriptional processes influencing phenotypic diversity as transcripts accurately predict the relative abundance of proteins in urine samples. The match between transcripts and urine samples taken six months earlier also emphasizes that the proportional relationships across central MUP isoforms in urine is stable. Balancing selection maintains coding variants at moderate frequencies, though pheromone diversity appears limited by interactions with vomeronasal receptors. We find that differential transcription of the central Mup paralogs within and between individuals significantly increases the individuality of pheromone blends. Balancing selection on gene regulation allows for increased individuality via combinatorial diversity in a limited number of pheromones.

EcoMark: Evaluating Models of Vehicular Environmental Impact

DEFF Research Database (Denmark)

Guo, Chenjuan; Ma, Mike; Yang, Bin

2012-01-01

The reduction of greenhouse gas (GHG) emissions from transporta- tion is essential for achieving politically agreed upon emissions re- duction targets that aim to combat global climate change. So-called eco-routing and eco-driving are able to substantially reduce GHG emissions caused by vehicular...... the vehicle travels in. We develop an evaluation framework, called EcoMark, for such environmental impact models. In addition, we survey all eleven state-of-the-art impact models known to us. To gain insight into the capabilities of the models and to understand the effectiveness of the EcoMark, we apply...

Using Marking Criteria to Improve Learning: An Evaluation of Student Perceptions

Directory of Open Access Journals (Sweden)

Swapna Koshy

2009-02-01

Full Text Available This paper is an exploratory study on the use of Marking Criteria in the offshore campus of an Australian University in the Middle East. The purpose of the study is to analyse student attitudes to the use of Marking Criteria with a view to maximizing its use. Most educators agree that assessment plays a key role in education and the use of Marking Criteria helps to streamline assessment. The study notes that most students were aware of the benefits of reviewing criteria before they worked on an assessment but few actually used it. The paper offers ways to help students internalise criteria to make learning effective. It also proposes the use of Marking Criteria as a tool that aids teachers in giving feedback in large classes.

Dispersal of butterflies in a New Guinea rainforest: using mark-recapture methods in a large, homogeneous habitat

Czech Academy of Sciences Publication Activity Database

Vlašánek, Petr; Sam, L.; Novotný, Vojtěch

2013-01-01

Roč. 38, č. 6 (2013), s. 560-569 ISSN 0307-6946 R&D Projects: GA ČR GA206/09/0115; GA ČR GAP505/10/0673; GA MŠk(CZ) LH11008 Grant - others:National Science Foundation(US) DEB-0841885; GA JU(CZ) 121/2010/P; GA JU(CZ) 136/2010/P; European Social Fund(CZ) CZ.1.07/2.3.00/20.0064 Institutional support: RVO:60077344 Keywords : Lepidoptera * lowland rainforest * mark-release-recapture Subject RIV: EH - Ecology, Behaviour Impact factor: 1.967, year: 2013 http://onlinelibrary.wiley.com/doi/10.1111/een.12051/pdf

Diverse and participative learning methodologies: a remedial teaching intervention for low marks dental students in Chile.

Science.gov (United States)

Alcota, Marcela; Muñoz, Andrea; González, Fermín E

2011-10-01

The purpose of this educational intervention was to diagnose the learning style of a group of low marks (i.e., grades) dental students in Chile and improve their academic achievement by means of remedial teaching. The intervention group was composed of ten students in endodontics and eleven in pedodontics with low marks. These two groups were mutually exclusive. The Kolb test of learning styles was applied to the low mark students group and to the rest of the class (n=72). Diverse methodologies were applied to the low marks students, such as seminars, case-based learning and problem-based learning, directed study, plenary discussions and debate, integration and questions, and web-based learning in an effort to cover all learning styles. Students' perceptions of the educational intervention were assessed by means of a questionnaire. The learning styles of the low marks group were mainly divergent (52.4 percent) and convergent (19 percent). Accommodators and assimilators were 14.3 percent each. The rest of the class showed a very distinct frequencies distribution: divergent 18 percent, convergent 20 percent, accommodators 28 percent, and assimilators 34 percent. After the educational intervention, the mean of the scores obtained by the intervention group in formal evaluations was higher than the average scores obtained before the intervention for both courses. Students' perceptions of the activities were that they were effective for their learning process (76 percent) and that the teaching methodologies were useful mainly to clarify concepts and contents from both courses (82 percent). We can conclude that the use of diverse and participative teaching methodologies in a remedial teaching intervention, to cover all the different learning styles of the students, contributes to improve their marks in formal evaluations.

49 CFR 172.301 - General marking requirements for non-bulk packagings.

Science.gov (United States)

2010-10-01

... Liquefied petroleum gas (LPG) unless it is legibly marked NON-ODORIZED or NOT ODORIZED in letters not less... empty packagings, see § 173.29 of this subchapter.) (f) NON-ODORIZED marking on cylinders containing LPG...

The cerebral functional location in normal subjects with Chinese classical national music auditory stimulus

International Nuclear Information System (INIS)

Sun Da; Xu Wei; Zhan Hongwei; Liu Hongbiao

2004-01-01

thalamic (in 1 case). Conclusion: During listening the Chinese classical national music and paying special attention to the imagination of music the auditory association cortex in the right and left superior temporal and midtemporal were activated. The inferior frontal and/or medial frontal lobes were activated too. And the activity was markedly higher in frontal than in temporal. According to the literatures, almost invariably, in any task which requires analysis of auditory information the posterior part of the inferior frontal gyms is activated. In the left hemisphere this region is often called Broca's area. The inferior frontal lobe, frontal eye field and superolateral prefrontal cortex are also related to mood and judgment. So it is not wonder that the frontal lobes showed as higher activity in these subjects. (authors)

27 CFR 28.216 - Export marks.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export marks. 28.216 Section 28.216 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS EXPORTATION OF ALCOHOL Exportation of Wine With Benefit of Drawback § 28.216...

StirMark Benchmark: audio watermarking attacks based on lossy compression

Science.gov (United States)

Steinebach, Martin; Lang, Andreas; Dittmann, Jana

2002-04-01

StirMark Benchmark is a well-known evaluation tool for watermarking robustness. Additional attacks are added to it continuously. To enable application based evaluation, in our paper we address attacks against audio watermarks based on lossy audio compression algorithms to be included in the test environment. We discuss the effect of different lossy compression algorithms like MPEG-2 audio Layer 3, Ogg or VQF on a selection of audio test data. Our focus is on changes regarding the basic characteristics of the audio data like spectrum or average power and on removal of embedded watermarks. Furthermore we compare results of different watermarking algorithms and show that lossy compression is still a challenge for most of them. There are two strategies for adding evaluation of robustness against lossy compression to StirMark Benchmark: (a) use of existing free compression algorithms (b) implementation of a generic lossy compression simulation. We discuss how such a model can be implemented based on the results of our tests. This method is less complex, as no real psycho acoustic model has to be applied. Our model can be used for audio watermarking evaluation of numerous application fields. As an example, we describe its importance for e-commerce applications with watermarking security.

Human papillomavirus genotypes and phylogenetic analysis of HPV-16 variants in HIV-1 infected subjects in Italy.

Science.gov (United States)

Tanzi, Elisabetta; Amendola, Antonella; Bianchi, Silvia; Fasolo, M Michela; Beretta, Rosangela; Pariani, Elena; Zappa, Alessandra; Frati, Elena; Orlando, Giovanna

2009-05-29

A cross-sectional study was carried out to improve the state of evidence regarding the spectrum of HPV types and HPV-16 LCR variants circulating among men and women infected with HIV-1 in Italy. This study, conducted in 518 HIV-positive subjects (346 males and 172 females), showed a high prevalence of HPV anal infections (88.7%) in men and of cervical infections (65.1%) in women. A wide spectrum of HPV genotypes has been observed, as both single and multiple infections. Low-risk HPV types 6, 11 and 61 were frequently detected. HPV-16 was the prevalent high-risk type. Fourteen different HPV-16 LCR variants were found. Ten belonged to the European lineage (78.7% were detected in Italian subjects and 21.3% in foreign-born, all homo/bisexual men), two to the Asiatic lineage and two to the African-2 lineage. This study underlines the great genotypic heterogeneity characterizing anal and cervical HPV infections and the marked polymorphism of the predominant HPV-16 in this high-risk population in Italy.

Isotopic marking and tracers

International Nuclear Information System (INIS)

Morel, F.

1997-01-01

The use of radioactive isotopes as tracers in biology has been developed thanks to the economic generation of the required isotopes in accelerators and nuclear reactors, and to the multiple applications of tracers in the life domain; the most usual isotopes employed in biology are carbon, hydrogen, phosphorus and sulfur isotopes, because these elements are present in most of organic molecules. Most of the life science knowledge appears to be dependent to the extensive use of nuclear tools and radioactive tracers; the example of the utilization of radioactive phosphorus marked ATP to study the multiple reactions with proteins, nucleic acids, etc., is given

Mechanistic spatio-temporal point process models for marked point processes, with a view to forest stand data

DEFF Research Database (Denmark)

Møller, Jesper; Ghorbani, Mohammad; Rubak, Ege Holger

We show how a spatial point process, where to each point there is associated a random quantitative mark, can be identified with a spatio-temporal point process specified by a conditional intensity function. For instance, the points can be tree locations, the marks can express the size of trees......, and the conditional intensity function can describe the distribution of a tree (i.e., its location and size) conditionally on the larger trees. This enable us to construct parametric statistical models which are easily interpretable and where likelihood-based inference is tractable. In particular, we consider maximum...

Trade reforms, mark-ups and bargaining power of workers: the case ...

African Journals Online (AJOL)

Ethiopian Journal of Economics ... workers between 1996 and 2007, a model of mark-up with labor bargaining power was estimated using random effects and LDPDM. ... Keywords: Trade reform, mark-up, bargaining power, rent, trade unions ...

The Symmetry in the Selected Plantar Pressure Distribution Parameters of the Elderly Subject With Lower Limb Discrepancy (LLD

Directory of Open Access Journals (Sweden)

Raghad Memar

2012-10-01

Full Text Available Objectives: lower leg discrepancy is a common problem which causes the changes in the plantar pressure distribution pattern during gait. Therefore, the purpose of this study was to study the symmetry in the various plantar pressure distribution parameters in the elderly subject with leg discrepancy. Methods & Materials: Twenty-one elderly from Esfehan with leg discrepancy (1.5 to 3 cm participated in this study. Plantar pressure distribution and other related parameters were measured in the five discrete steps for each limb by “emed 2” platforms. Three successful steps from five were selected and averaged, and the plantar areas were divided into 11 marks. For each mark peak force (BW%, peak pressure (Kpa, contact area, contact time, pressure time integral and force time integral were calculated. Descriptive statistics (mean and SD to report the plantar pressure pattern, dependent sample t- test for comparison pressure data between long and short limb (P≤0.05 and symmetry index (SI% for the symmetrical status in the selected plantar pressure data of the elderly subject with LLD were used. Results: The consequence of dependent t-test showed that regardless of contact area in the forefoot region and 3th, 4th and 5th toes, there were no significant differences between long and short limb. Symmetry index (SI% also revealed that the contact time in the short limbs heel was less than long limb and peak force and peak pressure in the short limb was less in mid foot region and was greater in forefoot region than long limb. Conclusion: Given The Result Of This Study Showed That In The Short Limb, Initial Contact Time And Weight Acceptance Was Reduced, Which Cause The Increase Of The Pressure In The Forefoot And Also Which Causes The Increase Of Stress Fracture Risk In The Metatarsal Region. Therefore, It Is Suggested That LLD Subject Use Orthotic Or Shoes That Can Increase Their Heel Height And Balancing The Contact Time In The Short Limb To Resolve

Mark II containment lead plant program load evaluation and acceptance criteria

International Nuclear Information System (INIS)

1978-10-01

The report, prepared by the Office of Nuclear Reactor Regulation, addresses the portion of the Mark II owner's program that provides a generic methodology for establishing design basis LOCA and safety relief valve loads for the lead Mark II facilities (Zimmer, Shoreham, and LaSalle), i.e., the lead plant program. The report includes an evaluation of the Mark II owner's load methodology, a description of load methodologies that we find acceptable for use in the individual plant unique assessments, and the basis for the stated conclusions

Marking pike fry otoliths with alizarin complexone and strontium : an evaluation of methods

DEFF Research Database (Denmark)

Skov, Christian; Grønkjær, P.; Nielsen, C.

2001-01-01

Laboratory experiments demonstrated that both alizarin complexone and strontium are useful in mass marking of pike Esox lucius fry otoliths. Visual detection of alizarin complexone marks was considered more reliable than the quantitative analysis of strontium for differentiating marked and unmarked...

Capitalist Discourse, Subjectivity and Lacanian Psychoanalysis

Science.gov (United States)

Vanheule, Stijn

2016-01-01

This paper studies how subjectivity in capitalist culture can be characterized. Building on Lacan's later seminars XVI, XVII, XVIII, and XIX, the author first outlines Lacan's general discourse theory, which includes four characteristic discourses: the discourse of the master, the discourse of the university, the discourse of the hysteric and the discourse of the analyst. Next, the author explores the subjectivity and the mode of dealing with jouissance and semblance, which is entailed in a fifth type of discourse, the capitalist discourse, discussed by Lacan (1972). Indeed, like the other discourses that Lacan discerns, the discourse of the capitalist can be thought of as a mode of dealing with the sexual non-rapport. It is argued that in the case of neurosis the discourse of the capitalist functions as an attempt to ignore the sexual non-rapport and the dimension of the unconscious. Psychosis, by contrast, is marked by an a priori exclusion from discourse. In that case, consumerist ways of relating to the other might offer a semblance, and thus the possibility of inventing a mode of relating to the other. Two clinical vignettes are presented to illustrate this perspective: one concerning the neurotic structure and one concerning the psychotic structure. PMID:28018280

Automated road marking recognition system

Science.gov (United States)

Ziyatdinov, R. R.; Shigabiev, R. R.; Talipov, D. N.

2017-09-01

Development of the automated road marking recognition systems in existing and future vehicles control systems is an urgent task. One way to implement such systems is the use of neural networks. To test the possibility of using neural network software has been developed with the use of a single-layer perceptron. The resulting system based on neural network has successfully coped with the task both when driving in the daytime and at night.

Strength analysis and optimization of writing mechanism of steel billet marking machine

Directory of Open Access Journals (Sweden)

Fu Min

2017-01-01

Full Text Available According to steel billet marking theory of plasma arc nicking, the paper designs a dual laser ranging marking machine against online marking of special steel billet and realizes multi-character marking of the end face of hot steel billet. Writing mechanism bases on the rectangular coordinates marking form, Z axis adopts cantilever structure. It completes the overall marking task utilizing the synergy of KK module in X axis, Y axis and Z axis. It makes modal analysis on the writing mechanism model established by Pro/Enginner utilizing ANSYS Workbench at the position of X1Y1Z1, and obtains the first six order modal frequency and analyzes the vibration in the writing process. Moreover, the paper analyzes the static structure of the cantilever of writing mechanism, computes its maximum stress and total deformation. To make the writing mechanism reach the target of light weight, the paper optimizes Z-axis cantilever of writing mechanism. According to the analysis, it is known that the optimized Z-axis cantilever of the writing mechanism still meets the strength and rigidity requirement and total mass declines approximately 30%.

Full-scale mark II CRT program facility description report

International Nuclear Information System (INIS)

Namatame, Ken; Kukita, Yutaka; Ito, Hideo; Yamamoto, Nobuo; Shiba, Masayoshi

1980-03-01

Started in fiscal year 1977, the Full-Scale Mark II CRT (Containment Response Test) Program is proceeding for the period of five years. The primary objective of the CRT Program is to provide a data base for evaluation of the pressure suppression pool hydrodynamic loads associated with a postulated loss-of-coolant accident in the BWR Mark II containment system. The test facility was designed and constructed from fiscal year 1977 to 1978, and completed in March 1979. It is 1/18 in volume and has a wetwell which is a full-scale replica of one 20 0 -sector of that of a reference Mark II. This report describes design concepts, dimensions and constructions of the test facility, as well as specifications, locations and installation schemes of the measuring equipments. Results of soil structure inspection, vacuum breaker test and shaker test of the containment shell are given in the appendices. (author)

Evaluation of the single radiosensitivity in patients subjected to medical exposure that show severe skin reactions; Evaluacion de la radiosensibilidad individual en pacientes sometidos a exposiciones medicas que manifiestan reacciones cutaneas severas

Energy Technology Data Exchange (ETDEWEB)

Di Giorgio, M; Vallerga, M B [Laboratorio de Dosimetria Biologica, Autoridad Regulatoria Nuclear, Av. Del Libertador 8250 (C1429BNP), Buenos Aires (Argentina); Portas, M [Hospital de Quemados del Gobierno de la Ciudad de Buenos Aires (Argentina); Perez, M R [Laboratorio de Radiopatologia, Autoridad Regulatoria Nuclear, Buenos Aires (Argentina)

2006-07-01

The Burnt Hospital of the Buenos Aires City Government (HQGCBA) it is a hospital of reference of the Net of Medical Responses in Radiological Emergencies of the Argentine Republic. In the mark of an agreement among the HQGCBA and the Authority Regulatory Nuclear (ARN), it is in execution a study protocol for the one boarding diagnoses and therapeutic of radioinduced cutaneous leisure. They exist individual variations that can condition the response to the ionizing radiations (IR), so much in accidental exposures as having programmed (radiotherapy, radiology interventionist). In this context, the individual radiosensitivity is evaluated in the patients signed up in this protocol that presented sharp or late cutaneous reactions, with grades of severity 3-4 (approaches EORTC/RTOG). The capacity of repair of the DNA was evaluated in outlying blood lymphocytes irradiated in vitro (2 Gy, gamma of Co-60) by means of the micronucleus techniques and comet essay in alkaline conditions. In this work two cases in those that is applied this study protocol, the therapeutic answer and its correlate with the discoveries of the radiosensitivity tests is presented. Case 1: patient of feminine sex, subjected to external radiotherapy by a breast infiltrating ductal carcinoma; developed sharp cutaneous radiotoxicity grade 3 (confluent humid epithelitis) that motivate the interruption of the treatment. Case 2: patient of masculine sex, subjected to a coronary angioplasty (interventionist radiology); developed late cutaneous radiotoxicity grade 4 (ulceration in dorsal region). Both patients were treated with topical trolamine associated to systemic administration of pentoxiphiline and antioxidants. The therapeutic answer is evaluated by means of clinical pursuit, photographic serial register and complementary exams (thermography and ultrasonography of high frequency). In the case 1 the answer was very favorable, with precocious local improvement and complete remission of symptoms and

First results from Mark III at SPEAR

International Nuclear Information System (INIS)

Einsweiler, K.F.

The paper presents data on meson decays obtained using the MARK III detector operating at SPEAR. Results on hadronic decays; decays of the etasub(e); and results on radiative decays; are all described. (U.K.)

The Four Marks of Holistic Kinesiology

Science.gov (United States)

Twietmeyer, Gregg

2012-01-01

What, to borrow a theological phrase, are the marks of a truly holistic kinesiology department? "In Kinesis and the Nature of the Human Person" (2010), I examined the theoretical impact of Aristotle's definition of "kinesis" and Polanyi's theory of "tacit knowledge" on kinesiology. The intention here, however, is practical rather than theoretical.…

Electrophysiology of subject-verb agreement mediated by speakers' gender.

Science.gov (United States)

Hanulíková, Adriana; Carreiras, Manuel

2015-01-01

An important property of speech is that it explicitly conveys features of a speaker's identity such as age or gender. This event-related potential (ERP) study examined the effects of social information provided by a speaker's gender, i.e., the conceptual representation of gender, on subject-verb agreement. Despite numerous studies on agreement, little is known about syntactic computations generated by speaker characteristics extracted from the acoustic signal. Slovak is well suited to investigate this issue because it is a morphologically rich language in which agreement involves features for number, case, and gender. Grammaticality of a sentence can be evaluated by checking a speaker's gender as conveyed by his/her voice. We examined how conceptual information about speaker gender, which is not syntactic but rather social and pragmatic in nature, is interpreted for the computation of agreement patterns. ERP responses to verbs disagreeing with the speaker's gender (e.g., a sentence including a masculine verbal inflection spoken by a female person 'the neighbors were upset because I (∗)stoleMASC plums') elicited a larger early posterior negativity compared to correct sentences. When the agreement was purely syntactic and did not depend on the speaker's gender, a disagreement between a formally marked subject and the verb inflection (e.g., the womanFEM (∗)stoleMASC plums) resulted in a larger P600 preceded by a larger anterior negativity compared to the control sentences. This result is in line with proposals according to which the recruitment of non-syntactic information such as the gender of the speaker results in N400-like effects, while formally marked syntactic features lead to structural integration as reflected in a LAN/P600 complex.

Eosinophilic myocarditis due to Churg-Strauss syndrome with markedly elevated eosinophil cationic protein.

Science.gov (United States)

Hara, Tomoya; Yamaguchi, Koji; Iwase, Takashi; Kadota, Muneyuki; Bando, Mika; Ogasawara, Kozue; Bando, Sachiko; Ise, Takayuki; Niki, Toshiyuki; Ueda, Yuka; Tomita, Noriko; Taketani, Yoshio; Yamada, Hirotsugu; Soeki, Takeshi; Wakatsuki, Tetsuzo; Sata, Masataka

2013-01-01

A 67-year-old woman with asthma visited our hospital with increasing dyspnea and new-onset paresthesia and purpura in her legs. Physical examination showed a wheeze, pretibial edema, and surrounding purpura. Chest X-rays showed cardiac decompensation and an electrocardiogram revealed a new ST-T change. Laboratory data showed leukocytosis, hypereosinophilia (10,450/μL), troponin T(+), elevated BNP, and markedly elevated eosinophil cationic protein (ECP) (> 150 ng/mL). Echocardiography revealed diffuse left ventricular hypokinesis (ejection fraction 30%) with increased wall thickness. Coronary angiography was normal. Cardiac magnetic resonance imaging implied diffuse myocardial edema and subendocardial late gadolinium enhancement. Skin biopsy of purpura showed superfi cial perivascular dermatitis with remarkable eosinophilic infiltrations. No evidence of drug allergies, parasitic infection, or myeloproliferative disorder was detected. Based on these findings, a diagnosis of eosinophilic myocarditis due to Churg-Strauss syndrome was considered. She was administered prednisolone at a dose of 1 mg/kg, cyclophosphamide, and diuretics. Several markers of eosinophilic myocarditis and heart failure gradually improved, including ECP. She was discharged 30 days later with no cardiac event. Eosinophilic myocarditis is characterized by predominantly eosinophilic infi ltration. Eosinophilic granule proteins, such as ECP and major basic protein, play important roles in the pathogenesis of eosinophilic myocarditis. We experienced a rare case of eosinophilic myocarditis due to Churg-Strauss syndrome. Markedly elevated ECP played an important role in the early diagnosis and subsequent reduction in ECP served as a marker of monitoring. In an asthmatic patient with dyspnea, hypereosinophilia, and vasculitis, Churg-Strauss syndrome with eosinophilic myocarditis should be considered.

User's guide : pavement marking management system database.

Science.gov (United States)

2011-12-01

Pavement markings play a critical role in maintaining a safe and efficient driving environment for road users, especially during nighttime conditions. The Texas Department of Transportation (TxDOT) spends millions of dollars each year for installatio...

Restoration of abraded and covered marks engraved in steel using active infrared thermography

DEFF Research Database (Denmark)

Quattrocchi, A.; Piccolo, Sebastiano; Montanini, R.

2016-01-01

Alphanumeric marking is a common technique employed in industrial applications for identification of products. However, the realised mark can undergo deterioration, either by extensive use or voluntary deletion (e.g. removal of identification numbers of weapons or vehicles). For recovery of the l......Alphanumeric marking is a common technique employed in industrial applications for identification of products. However, the realised mark can undergo deterioration, either by extensive use or voluntary deletion (e.g. removal of identification numbers of weapons or vehicles). For recovery...

Teaching Mark through a postcolonial optic

African Journals Online (AJOL)

2015-07-16

Jul 16, 2015 ... question, eliciting answers that range from Mark as in direct and open ... or armed response, especially in a context where such actions were unrealistic. (whether ..... identity; social memory; to name a few) of power. It implies ... an elite-driven enterprise in the simplistic sense of the word, although the elite's ...

49 CFR 15.13 - Marking SSI.

Science.gov (United States)

2010-10-01

... SSI. (a) Marking of paper records. In the case of paper records containing SSI, a covered person must... limitation statement on the bottom, of— (1) The outside of any front and back cover, including a binder cover... types of records. In the case of non-paper records that contain SSI, including motion picture films...

Primary Science Quality Mark--2016 Update

Science.gov (United States)

Turner, Jane

2016-01-01

Back in May 2011, an article in "Primary Science" described how the idea for a quality mark for primary science was developed from an initial conversation at an Association for Science Education annual conference (Turner, Marshall and Elsmore, 2011). Its intention then, as now, was to support and champion good practice and raise the…

Meet EPA Chemist Mark Strynar, Ph.D.

Science.gov (United States)

Dr. Mark Strynar is a physical scientist in EPA's Office of Research and Development. His research interests include developing methods to measure and analyze the movement of PFCs and other xenobiotic compounds in biological and environmental media

Technical specifications manual for the MARK-1 pulsed ionizing radiation detection system

International Nuclear Information System (INIS)

Lawrence, R.S.; Harker, Y.D.; Jones, J.L.; Hoggan, J.M.

1993-03-01

The MARK-1 detection system was developed by the Idaho National Engineering Laboratory for the US Department of Energy Office of Arms Control and Nonproliferation. The completely portable system was designed for the detection and analysis of intense photon emissions from pulsed ionizing radiation sources. This manual presents the technical design specifications for the MARK-1 detection system and was written primarily to assist the support or service technician in the service, calibration, and repair of the system. The manual presents the general detection system theory, the MARK-1 component design specifications, the acquisition and control software, the data processing sequence, and the system calibration procedure. A second manual entitled: Volume 2: Operations Manual for the MARK-1 Pulsed Ionizing Radiation Detection System (USDOE Report WINCO-1108, September 1992) provides a general operational description of the MARK-1 detection system. The Operations Manual was written primarily to assist the field operator in system operations and analysis of the data

Optical diameters of stars measured with the Mt. Wilson Mark III interferometer

International Nuclear Information System (INIS)

Simon, R.S.; Mozurkewich, D.; Johnston, K.J.; Gaume, R.; Hutter, D.J.; Bowers, P.F.; Colavita, M.M.; Shao, M.

1990-01-01

Reliable stellar angular diameters can now be determined using the Mark III Optical Interferometer located on Mt. Wilson, California. The Mark III is a Michelson Interferometer capable of measuring the interferometric fringe visibility for stars using interferometer baselines varying from 3 to 31.5 meters in length. Angular diameters measured with the Mark III Optical Interferometer are presented for 12 stars at wavelengths of 450 and 800 nm. 10 refs

Multiple data sources improve DNA-based mark-recapture population estimates of grizzly bears.

Science.gov (United States)

Boulanger, John; Kendall, Katherine C; Stetz, Jeffrey B; Roon, David A; Waits, Lisette P; Paetkau, David

2008-04-01

A fundamental challenge to estimating population size with mark-recapture methods is heterogeneous capture probabilities and subsequent bias of population estimates. Confronting this problem usually requires substantial sampling effort that can be difficult to achieve for some species, such as carnivores. We developed a methodology that uses two data sources to deal with heterogeneity and applied this to DNA mark-recapture data from grizzly bears (Ursus arctos). We improved population estimates by incorporating additional DNA "captures" of grizzly bears obtained by collecting hair from unbaited bear rub trees concurrently with baited, grid-based, hair snag sampling. We consider a Lincoln-Petersen estimator with hair snag captures as the initial session and rub tree captures as the recapture session and develop an estimator in program MARK that treats hair snag and rub tree samples as successive sessions. Using empirical data from a large-scale project in the greater Glacier National Park, Montana, USA, area and simulation modeling we evaluate these methods and compare the results to hair-snag-only estimates. Empirical results indicate that, compared with hair-snag-only data, the joint hair-snag-rub-tree methods produce similar but more precise estimates if capture and recapture rates are reasonably high for both methods. Simulation results suggest that estimators are potentially affected by correlation of capture probabilities between sample types in the presence of heterogeneity. Overall, closed population Huggins-Pledger estimators showed the highest precision and were most robust to sparse data, heterogeneity, and capture probability correlation among sampling types. Results also indicate that these estimators can be used when a segment of the population has zero capture probability for one of the methods. We propose that this general methodology may be useful for other species in which mark-recapture data are available from multiple sources.

XML schemas and mark-up practices of taxonomic literature.

Science.gov (United States)

Penev, Lyubomir; Lyal, Christopher Hc; Weitzman, Anna; Morse, David R; King, David; Sautter, Guido; Georgiev, Teodor; Morris, Robert A; Catapano, Terry; Agosti, Donat

2011-01-01

We review the three most widely used XML schemas used to mark-up taxonomic texts, TaxonX, TaxPub and taXMLit. These are described from the viewpoint of their development history, current status, implementation, and use cases. The concept of "taxon treatment" from the viewpoint of taxonomy mark-up into XML is discussed. TaxonX and taXMLit are primarily designed for legacy literature, the former being more lightweight and with a focus on recovery of taxon treatments, the latter providing a much more detailed set of tags to facilitate data extraction and analysis. TaxPub is an extension of the National Library of Medicine Document Type Definition (NLM DTD) for taxonomy focussed on layout and recovery and, as such, is best suited for mark-up of new publications and their archiving in PubMedCentral. All three schemas have their advantages and shortcomings and can be used for different purposes.

Unusual idiopathic normal pressure hydrocephalus patient with marked asymmetric and upper body parkinsonism

Directory of Open Access Journals (Sweden)

Kyunghun Kang

2016-01-01

Full Text Available Asymmetry of parkinsonian symptoms is strong evidence toward the diagnosis of Parkinson's disease (PD. Lower body parkinsonism is characteristic in idiopathic normal pressure hydrocephalus (INPH. We report an unusual INPH patient with marked asymmetric and upper body parkinsonism. An 83-year-old man presented with gait impairment and asymmetric clumsiness of movement. According to the Unified Parkinson's Disease Rating Scale (UPDRS, the motor subscore was 12 in the left limb and 8 in the right. The score was 14 for both the upper and lower body. After the cerebrospinal fluid tap test (CSFTT, he showed marked improvement in the upper body score. A loss of asymmetry of parkinsonian signs, with greater improvement in the left limb, was presented. Fluorinated N-3-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl-nortropane (F-18 FP-CIT positron emission tomography (PET imaging was normal. In the differential diagnosis of elderly patients presenting with parkinsonism compatible with PD, we might need to consider a diagnosis of INPH.

Mutations in HNF1A Result in Marked Alterations of Plasma Glycan Profile

Science.gov (United States)

Thanabalasingham, Gaya; Huffman, Jennifer E.; Kattla, Jayesh J.; Novokmet, Mislav; Rudan, Igor; Gloyn, Anna L.; Hayward, Caroline; Adamczyk, Barbara; Reynolds, Rebecca M.; Muzinic, Ana; Hassanali, Neelam; Pucic, Maja; Bennett, Amanda J.; Essafi, Abdelkader; Polasek, Ozren; Mughal, Saima A.; Redzic, Irma; Primorac, Dragan; Zgaga, Lina; Kolcic, Ivana; Hansen, Torben; Gasperikova, Daniela; Tjora, Erling; Strachan, Mark W.J.; Nielsen, Trine; Stanik, Juraj; Klimes, Iwar; Pedersen, Oluf B.; Njølstad, Pål R.; Wild, Sarah H.; Gyllensten, Ulf; Gornik, Olga; Wilson, James F.; Hastie, Nicholas D.; Campbell, Harry; McCarthy, Mark I.; Rudd, Pauline M.; Owen, Katharine R.; Lauc, Gordan; Wright, Alan F.

2013-01-01

A recent genome-wide association study identified hepatocyte nuclear factor 1-α (HNF1A) as a key regulator of fucosylation. We hypothesized that loss-of-function HNF1A mutations causal for maturity-onset diabetes of the young (MODY) would display altered fucosylation of N-linked glycans on plasma proteins and that glycan biomarkers could improve the efficiency of a diagnosis of HNF1A-MODY. In a pilot comparison of 33 subjects with HNF1A-MODY and 41 subjects with type 2 diabetes, 15 of 29 glycan measurements differed between the two groups. The DG9-glycan index, which is the ratio of fucosylated to nonfucosylated triantennary glycans, provided optimum discrimination in the pilot study and was examined further among additional subjects with HNF1A-MODY (n = 188), glucokinase (GCK)-MODY (n = 118), hepatocyte nuclear factor 4-α (HNF4A)-MODY (n = 40), type 1 diabetes (n = 98), type 2 diabetes (n = 167), and nondiabetic controls (n = 98). The DG9-glycan index was markedly lower in HNF1A-MODY than in controls or other diabetes subtypes, offered good discrimination between HNF1A-MODY and both type 1 and type 2 diabetes (C statistic ≥0.90), and enabled us to detect three previously undetected HNF1A mutations in patients with diabetes. In conclusion, glycan profiles are altered substantially in HNF1A-MODY, and the DG9-glycan index has potential clinical value as a diagnostic biomarker of HNF1A dysfunction. PMID:23274891

Optical study on the dependence of breast tissue composition and structure on subject anamnesis

Science.gov (United States)

Taroni, Paola; Quarto, Giovanna; Pifferi, Antonio; Abbate, Francesca; Balestreri, Nicola; Menna, Simona; Cassano, Enrico; Cubeddu, Rinaldo

2015-07-01

Time domain multi-wavelength (635 to 1060 nm) optical mammography was performed on 200 subjects to estimate their average breast tissue composition in terms of oxy- and deoxy-hemoglobin, water, lipid and collagen, and structural information, as provided by scattering parameters (amplitude and power). Significant (and often marked) dependence of tissue composition and structure on age, menopausal status, body mass index, and use of oral contraceptives was demonstrated.

[Tattooing and its significance in Switzerland. A representative study of 2177 20-year-old Swiss subjects].

Science.gov (United States)

Haefeli, W E

1990-03-03

To investigate the incidence, significance and symbolism of tattooing in Switzerland, a representative group of 2177 young males (all liable for military service, age 19-21 years) were examined in 1988. All tattoos were sketched, the location was recorded and the individual meaning was discussed with the bearer. 135 subjects (6.2%) had 1-9 tattoos per person, showing 155 different marks. Only 13% of all tattoos were professional, moderate to large in size and most often located in the area of the upper arm and the shoulder. 87% of tattoos were self-inflicted or placed by a friend and the left side was therefore preferred (66%). In general, these were small to moderate in size, simple in design, and usually located on the forearm and the hand. The dominant significance of all tattoos was related to mental attitude (29%) and love affairs (14%). 13% were pictorial. Some were related to drug abuse, criminality of gangs, or contained magic symbolism or personal data such as zodiac signs and initials (about 4% each). Only 20% had no conventional or private meaning or involved concealed symbolism. For further understanding of the individuals' social history, it should be noted that some tattoos were characterized by minor differences of meaning, such as the "man-in-4-walls" mark (= prison), the "fuck-the-police" mark, the leaf of cannabis sativa or different cross motifs. Even greater consistency related to tattoos located in the web space between the thumb and the forefinger or on the back of the fingers. The location in itself may therefore provide additional personal information on individual circumstances at the time of tattooing.

Interview with Professor Mark Wilcox.

Science.gov (United States)

Wilcox, Mark

2016-08-01

Mark Wilcox speaks to Georgia Patey, Commissioning Editor: Professor Mark Wilcox is a Consultant Microbiologist and Head of Microbiology at the Leeds Teaching Hospitals (Leeds, UK), the Professor of Medical Microbiology at the University of Leeds (Leeds, UK), and is the Lead on Clostridium difficile and the Head of the UK C. difficile Reference Laboratory for Public Health England (PHE). He was the Director of Infection Prevention (4 years), Infection Control Doctor (8 years) and Clinical Director of Pathology (6 years) at the Leeds Teaching Hospitals. He is Chair of PHE's Rapid Review Panel (reviews utility of infection prevention and control products for National Health Service), Deputy Chair of the UK Department of Health's Antimicrobial Resistance and Healthcare Associated Infection Committee and a member of PHE's HCAI/AR Programme Board. He is a member of UK/European/US working groups on C. difficile infection. He has provided clinical advice as part of the FDA/EMA submissions for the approval of multiple novel antimicrobial agents. He heads a healthcare-associated infection research team at University of Leeds, comprising approximately 30 doctors, scientists and nurses; projects include multiple aspects of C. difficile infection, diagnostics, antimicrobial resistance and the clinical development of new antimicrobial agents. He has authored more than 400 publications, and is the coeditor of Antimicrobial Chemotherapy (5th/6th/7th Editions, 15 December 2007).

Marked exacerbation of orthostatic intolerance after long- vs. short-duration spaceflight in veteran astronauts

Science.gov (United States)

Meck, J. V.; Reyes, C. J.; Perez, S. A.; Goldberger, A. L.; Ziegler, M. G.

2001-01-01

OBJECTIVE: The incidence of postflight orthostatic intolerance after short-duration spaceflight is about 20%. However, the incidence after long-duration spaceflight was unknown. The purpose of this study was to test the hypothesis that orthostatic intolerance is more severe after long-duration than after short-duration flight. METHODS: We performed tilt tests on six astronauts before and after long-duration (129-190 days) spaceflights and compared these data with data obtained during stand tests before and after previous short-duration missions. RESULTS: Five of the six astronauts studied became presyncopal during tilt testing after long-duration flights. Only one had become presyncopal during stand testing after short-duration flights. We also compared the long-duration flight tilt test data to tilt test data from 20 different astronauts who flew on the short-duration Shuttle missions that delivered and recovered the astronauts to and from the Mir Space Station. Five of these 20 astronauts became presyncopal on landing day. Heart rate responses to tilt were no different between astronauts on long-duration flights and astronauts on short-duration flights, but long-duration subjects had lower stroke volumes and cardiac outputs than short-duration presyncopal subjects, suggesting a possible decrease in cardiac contractile function. One subject had subnormal norepinephrine release with upright posture after the long flight but not after the short flight. Plasma volume losses were not greater after long flights. CONCLUSION: Long-duration spaceflight markedly increases orthostatic intolerance, probably with multiple contributing factors.

Nekroloog turundusele / Mark Earls ; interv. Margo Kokerov

Index Scriptorium Estoniae

Earls, Mark

2003-01-01

Turunduskommunikatsioonifirma Ogilvy & Mather suunajuht Mark Earls leiab, et kuna turg on üle ujutatud võrdselt heade toodetega ja tarbija teab, et tegelikult pole oluline, millise toote ta valib, muutub turundusrevolutsiooni keskne idee - tarbijavajaduste kindlakstegemine ja rahuldamine - tähtsusetuks.

49 CFR 192.63 - Marking of materials.

Science.gov (United States)

2010-10-01

... Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Materials § 192.63 Marking of materials. (a) Except as...

27 CFR 20.178 - Marks and brands on containers of specially denatured spirits.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Marks and brands on... Dealers § 20.178 Marks and brands on containers of specially denatured spirits. (a) Required marks. Each... officer, or (2) Consist of a brand name, or consist of caution notices, or consist of other material...

75 FR 59102 - Defense Federal Acquisition Regulation Supplement; Government-Assigned Serial Number Marking...

Science.gov (United States)

2010-09-27

... version of MIL-STD-130, Marking of U.S. Military Property, shall be used for the marking of human-readable... Valuation; and (2) Require the contractor to mark major end items under the terms and conditions of the... revising the introductory text to read as follows: 252.211-7003 Item identification and valuation. As...

Bad faith trade mark applications in China : a threat to foreign investment?

OpenAIRE

Elftorp, Kristian

2012-01-01

In a report provided by the European Chamber of Commerce in China, the problem with bad faith trade mark applications was highlighted. The report concluded that the current application of the law, combined with the procedural background constitutes an incentive rather than a deterrent for bad faith trade mark applications in China. The issue originates in Chinese defrauders conducting research among foreign companies with the intent of un- lawfully registering their trade marks in China. Sinc...

Kuosheng Mark III containment analyses using GOTHIC

Energy Technology Data Exchange (ETDEWEB)

Lin, Ansheng, E-mail: samuellin1999@iner.gov.tw; Chen, Yen-Shu; Yuann, Yng-Ruey

2013-10-15

Highlights: • The Kuosheng Mark III containment model is established using GOTHIC. • Containment pressure and temperature responses due to LOCA are presented. • The calculated results are all below the design values and compared with the FSAR results. • The calculated results can be served as an analysis reference for an SPU project in the future. -- Abstract: Kuosheng nuclear power plant in Taiwan is a twin-unit BWR/6 plant, and both units utilize the Mark III containment. Currently, the plant is performing a stretch power uprate (SPU) project to increase the core thermal power to 103.7% OLTP (original licensed thermal power). However, the containment response in the Kuosheng Final Safety Analysis Report (FSAR) was completed more than twenty-five years ago. The purpose of this study is to establish a Kuosheng Mark III containment model using the containment program GOTHIC. The containment pressure and temperature responses under the design-basis accidents, which are the main steam line break (MSLB) and the recirculation line break (RCLB) accidents, are investigated. Short-term and long-term analyses are presented in this study. The short-term analysis is to calculate the drywell peak pressure and temperature which happen in the early stage of the LOCAs. The long-term analysis is to calculate the peak pressure and temperature of the reactor building space. In the short-term analysis, the calculated peak drywell to wetwell differential pressure is 140.6 kPa for the MSLB, which is below than the design value of 189.6 kPa. The calculated peak drywell temperature is 158 °C, which is still below the design value of 165.6 °C. In addition, in the long-term analysis, the calculated peak containment pressure is 47 kPa G, which is below the design value of 103.4 kPa G. The calculated peak values of containment temperatures are 74.7 °C, which is lower than the design value of 93.3 °C. Therefore, the Kuosheng Mark III containment can maintain the integrity after

The specification and global reprogramming of histone epigenetic marks during gamete formation and early embryo development in C. elegans.

Directory of Open Access Journals (Sweden)

Mark Samson

2014-10-01

Full Text Available In addition to the DNA contributed by sperm and oocytes, embryos receive parent-specific epigenetic information that can include histone variants, histone post-translational modifications (PTMs, and DNA methylation. However, a global view of how such marks are erased or retained during gamete formation and reprogrammed after fertilization is lacking. To focus on features conveyed by histones, we conducted a large-scale proteomic identification of histone variants and PTMs in sperm and mixed-stage embryo chromatin from C. elegans, a species that lacks conserved DNA methylation pathways. The fate of these histone marks was then tracked using immunostaining. Proteomic analysis found that sperm harbor ∼2.4 fold lower levels of histone PTMs than embryos and revealed differences in classes of PTMs between sperm and embryos. Sperm chromatin repackaging involves the incorporation of the sperm-specific histone H2A variant HTAS-1, a widespread erasure of histone acetylation, and the retention of histone methylation at sites that mark the transcriptional history of chromatin domains during spermatogenesis. After fertilization, we show HTAS-1 and 6 histone PTM marks distinguish sperm and oocyte chromatin in the new embryo and characterize distinct paternal and maternal histone remodeling events during the oocyte-to-embryo transition. These include the exchange of histone H2A that is marked by ubiquitination, retention of HTAS-1, removal of the H2A variant HTZ-1, and differential reprogramming of histone PTMs. This work identifies novel and conserved features of paternal chromatin that are specified during spermatogenesis and processed in the embryo. Furthermore, our results show that different species, even those with diverged DNA packaging and imprinting strategies, use conserved histone modification and removal mechanisms to reprogram epigenetic information.

Comparison of the reference mark azimuth determination methods

Directory of Open Access Journals (Sweden)

Danijel Šugar

2013-03-01

Full Text Available The knowledge of the azimuth of the reference mark is of crucial importance in the determination of the declination which is defined as the ellipsoidal (geodetic azimuth of the geomagnetic meridian. The accuracy of the azimuth determination has direct impact on the accuracy of the declination. The orientation of the Declination-Inclination Magnetometer is usually carried out by sighting the reference mark in two telescope faces in order to improve the reliability of the observations and eliminate some instrumental errors. In this paper, different coordinate as well as azimuth determination methods using GNSS (Global Navigation Satellite System observation techniques within VPPS (High-Precision Positioning Service and GPPS (Geodetic-Precision Positioning Service services of the CROPOS (CROatian POsitioning System system were explained. The azimuth determination by the observation of the Polaris was exposed and it was subsequently compared with the observation of the Sun using hour-angle and zenith-distance method. The procedure of the calculation of the geodetic azimuth from the astronomic azimuth was explained. The azimuth results obtained by different methods were compared and the recommendations on the minimal distance between repeat station and azimuth mark were given. The results shown in this paper were based on the observations taken on the POKU_SV repeat station.

Fingerprint Analysis with Marked Point Processes

DEFF Research Database (Denmark)

Forbes, Peter G. M.; Lauritzen, Steffen; Møller, Jesper

We present a framework for fingerprint matching based on marked point process models. An efficient Monte Carlo algorithm is developed to calculate the marginal likelihood ratio for the hypothesis that two observed prints originate from the same finger against the hypothesis that they originate from...... different fingers. Our model achieves good performance on an NIST-FBI fingerprint database of 258 matched fingerprint pairs....

38 CFR 3.2130 - Will VA accept a signature by mark or thumbprint?

Science.gov (United States)

2010-07-01

... signature by mark or thumbprint? 3.2130 Section 3.2130 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF... of This Title General § 3.2130 Will VA accept a signature by mark or thumbprint? VA will accept signatures by mark or thumbprint if: (a) They are witnessed by two people who sign their names and give their...

19 CFR 134.47 - Souvenirs and articles marked with trademarks or trade names.

Science.gov (United States)

2010-04-01

... 19 Customs Duties 1 2010-04-01 2010-04-01 false Souvenirs and articles marked with trademarks or... Imported Articles § 134.47 Souvenirs and articles marked with trademarks or trade names. When as part of a trademark or trade name or as part of a souvenir marking, the name of a location in the United States or...

Identification marking by means of laser peening

Science.gov (United States)

Hackel, Lloyd A.; Dane, C. Brent; Harris, Fritz

2002-01-01

The invention is a method and apparatus for marking components by inducing a shock wave on the surface that results in an indented (strained) layer and a residual compressive stress in the surface layer. One embodiment of the laser peenmarking system rapidly imprints, with single laser pulses, a complete identification code or three-dimensional pattern and leaves the surface in a state of deep residual compressive stress. A state of compressive stress in parts made of metal or other materials is highly desirable to make them resistant to fatigue failure and stress corrosion cracking. This process employs a laser peening system and beam spatial modulation hardware or imaging technology that can be setup to impress full three dimensional patterns into metal surfaces at the pulse rate of the laser, a rate that is at least an order of magnitude faster than competing marking technologies.

A less field-intensive robust design for estimating demographic parameters with Mark-resight data

Science.gov (United States)

McClintock, B.T.; White, Gary C.

2009-01-01

The robust design has become popular among animal ecologists as a means for estimating population abundance and related demographic parameters with mark-recapture data. However, two drawbacks of traditional mark-recapture are financial cost and repeated disturbance to animals. Mark-resight methodology may in many circumstances be a less expensive and less invasive alternative to mark-recapture, but the models developed to date for these data have overwhelmingly concentrated only on the estimation of abundance. Here we introduce a mark-resight model analogous to that used in mark-recapture for the simultaneous estimation of abundance, apparent survival, and transition probabilities between observable and unobservable states. The model may be implemented using standard statistical computing software, but it has also been incorporated into the freeware package Program MARK. We illustrate the use of our model with mainland New Zealand Robin (Petroica australis) data collected to ascertain whether this methodology may be a reliable alternative for monitoring endangered populations of a closely related species inhabiting the Chatham Islands. We found this method to be a viable alternative to traditional mark-recapture when cost or disturbance to species is of particular concern in long-term population monitoring programs. ?? 2009 by the Ecological Society of America.

Markedly Lower Glutamic Acid Decarboxylase 67 Protein Levels in a Subset of Boutons in Schizophrenia.

Science.gov (United States)

Rocco, Brad R; Lewis, David A; Fish, Kenneth N

2016-06-15

Convergent findings indicate that cortical gamma-aminobutyric acid (GABA)ergic circuitry is altered in schizophrenia. Postmortem studies have consistently found lower levels of glutamic acid decarboxylase 67 (GAD67) messenger RNA (mRNA) in the prefrontal cortex (PFC) of subjects with schizophrenia. At the cellular level, the density of GABA neurons with detectable levels of GAD67 mRNA is ~30% lower across cortical layers. Knowing how this transcript deficit translates to GAD67 protein levels in axonal boutons is important for understanding the impact it might have on GABA synthesis. In addition, because reductions in GAD67 expression before, but not after, the maturation of GABAergic boutons results in a lower density of GABAergic boutons in mouse cortical cultures, knowing if GABAergic bouton density is altered in schizophrenia would provide insight into the timing of the GAD67 deficit. PFC tissue sections from 20 matched pairs of schizophrenia and comparison subjects were immunolabeled for the vesicular GABA transporter (vGAT) and GAD67. vGAT+ bouton density did not differ between subject groups, consistent with findings that vGAT mRNA levels are unaltered in the illness and confirming that the number of cortical GABAergic boutons is not lower in schizophrenia. In contrast, in schizophrenia subjects, the proportion of vGAT+ boutons with detectable GAD67 levels (vGAT+/GAD67+ boutons) was 16% lower and mean GAD67 levels were 14% lower in the remaining vGAT+/GAD67+ boutons. Our findings suggest that GABA production is markedly reduced in a subset of boutons in the PFC of schizophrenia subjects and that this reduction likely occurs after the maturation of GABAergic boutons. Copyright © 2016 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

Identification of the Nile crocodile Crocodylus niloticus by the use of natural tail marks

Directory of Open Access Journals (Sweden)

D.G.J. Swanepoel

1996-08-01

Full Text Available The tail marks of 190 Nile crocodiles Crocodylus niloticus were documented and processed into codes. The size of the crocodiles varied from 45 cm to 4.6 m in total length. Wherever possible, both sides of the tails were observed and the marks documented. In all remaining instances only one side could be identified. A total of 267 sides were identified. The natural marks on nine segments of a specific portion of the tail was recorded and compared as codes. For this comparison two methods were employed. Differences of 95.1 and 100 was found with the respective methods. This is an indication that every crocodile has a unique pattern of natural marks on its tail. The marks can therefore be used to allocate a code to an individual crocodile that partially eliminates the necessity of artificial marking methods.

Identification of the Nile crocodile Crocodylus niloticus by the use of natural tail marks

Directory of Open Access Journals (Sweden)

D.G.J. Swanepoel

1996-01-01

Full Text Available The tail marks of 190 Nile crocodiles Crocodylus niloticus were documented and processed into codes. The size of the crocodiles varied from 45 cm to 4.6 m in total length. Wherever possible, both sides of the tails were observed and the marks documented. In all remaining instances only one side could be identified. A total of 267 sides were identified. The natural marks on nine segments of a specific portion of the tail was recorded and compared as codes. For this comparison two methods were employed. Differences of 95.1 and 100 was found with the respective methods. This is an indication that every crocodile has a unique pattern of natural marks on its tail. The marks can therefore be used to allocate a code to an individual crocodile that partially eliminates the necessity of artificial marking methods.

7 CFR 56.37 - Lot marking of officially identified shell eggs.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Lot marking of officially identified shell eggs. 56.37... AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) VOLUNTARY GRADING OF SHELL EGGS Grading of Shell Eggs Identifying and Marking Products § 56.37...

Recent results for Mark III

International Nuclear Information System (INIS)

Brient, J.C.

1987-12-01

This paper presents recent results from the Mark III detector at SPEAR, in the open charm sector. The first topic discussed is the reanalysis of the direct measurement of the D hadronic branching fractions, where a detailed study has been made of the Cabibbo suppressed and multi-π 0 's D decays backgrounds in the double tag sample. Next, the Dalitz plot analysis of the D decays to Kππ is presented, leading to the relative fractions of three-body versus pseudoscalarvector decays. 7 refs., 5 figs

The Five Marks of the Mental

Science.gov (United States)

Pernu, Tuomas K.

2017-01-01

The mental realm seems different to the physical realm; the mental is thought to be dependent on, yet distinct from the physical. But how, exactly, are the two realms supposed to be different, and what, exactly, creates the seemingly insurmountable juxtaposition between the mental and the physical? This review identifies and discusses five marks of the mental, features that set characteristically mental phenomena apart from the characteristically physical phenomena. These five marks (intentionality, consciousness, free will, teleology, and normativity) are not presented as a set of features that define mentality. Rather, each of them is something we seem to associate with phenomena we consider mental, and each of them seems to be in tension with the physical view of reality in its own particular way. It is thus suggested how there is no single mind-body problem, but a set of distinct but interconnected problems. Each of these separate problems is analyzed, and their differences, similarities and connections are identified. This provides a useful basis for future theoretical work on psychology and philosophy of mind, that until now has too often suffered from unclarities, inadequacies, and conflations. PMID:28736537

Electrophysiology of subject-verb agreement mediated by speakers’ gender

Directory of Open Access Journals (Sweden)

Adriana eHanulíková

2015-09-01

Full Text Available An important property of speech is that it explicitly conveys features of a speaker's identity such as age or gender. This event-related potential (ERP study examined the effects of social information provided by a speaker’s gender, i.e. the conceptual representation of gender, on subject-verb agreement. Despite numerous studies on agreement, little is known about syntactic computations generated by speaker characteristics extracted from the acoustic signal. Slovak is well suited to investigate this issue because it is a morphologically rich language in which agreement involves features for number, case, and gender. Grammaticality of a sentence can be evaluated by checking a speaker’s gender as conveyed by his/her voice. We examined how conceptual information about speaker gender, which is not syntactic but rather social and pragmatic in nature, is interpreted for the computation of agreement patterns. ERP responses to verbs disagreeing with the speaker's gender (e.g., a sentence including a masculine verbal inflection spoken by a female person 'the neighbours were upset because I *stoleMASC plums’ elicited a larger early posterior negativity compared to correct sentences. When the agreement was purely syntactic and did not depend on the speaker’s gender, a disagreement between a formally-marked subject and the verb inflection (e.g., the womanFEM *stoleMASC plums resulted in a larger P600 preceded by a larger anterior negativity compared to the control sentences. This result is in line with proposals according to which the recruitment of non-syntactic information such as the gender of the speaker results in N400-like effects, while formally-marked syntactic features lead to structural integration as reflected in a LAN/P600 complex.

Marketing support of putting on the own trade marks in the retail sector

Directory of Open Access Journals (Sweden)

Firsova S.

2013-02-01

Full Text Available The article summarizes the practical experience of putting own trade mark by the domestic enterprise on the food market of Ukraine. The author has investigated the marketing strategy of putting on the own trade mark and evaluated its results for the enterprise, formed and implemented to the practice the measures for evaluating the attractiveness of company’s own trade mark.

Computer-Aided Detection in Digital Mammography: False-Positive Marks and Their Reproducibility in Negative Mammograms

International Nuclear Information System (INIS)

Kim, Seung Ja; Moon, Woo Kyung; Cho, Nariya; Chang, Jung Min; Seong, Min Hyun

2009-01-01

Background: There are relatively few studies reporting the frequency of false-positive computer-aided detection (CAD) marks and their reproducibility in normal cases. Purpose: To evaluate retrospectively the false-positive mark rate of a CAD system and the reproducibility of false-positive marks in two sets of negative digital mammograms. Material and Methods: Two sets of negative digital mammograms were obtained in 360 women (mean age 57 years, range 30-76 years) with an approximate interval of 1 year (mean time 343.7 days), and a CAD system was applied. False-positive CAD marks and the reproducibility were determined. Results: Of the 360 patients, 252 (70.0%) and 240 (66.7%) patients had 1-7 CAD marks on the initial and second mammograms, respectively. The false-positive CAD mark rate was 1.5 (1.1 for masses and 0.4 for calcifications) and 1.4 (1.0 for masses and 0.4 for calcifications) per examination in the initial and second mammograms, respectively. The reproducibility of the false-positive CAD marks was 12.0% for both mass (81/680) and microcalcification (33/278) marks. Conclusion: False-positive CAD marks were seen in approximately 70% of normal cases. However, the reproducibility was very low. Radiologists must be familiar with the findings of false-positive CAD marks, since they are very common and can increase the recall rate in screening

9 CFR 310.6 - Carcasses and parts passed for cooking; marking.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Carcasses and parts passed for cooking... INSPECTION AND CERTIFICATION POST-MORTEM INSPECTION § 310.6 Carcasses and parts passed for cooking; marking. Carcasses and parts passed for cooking shall be marked conspicuously on the surface tissues thereof by a...

Viktor Misiano kureerib Mark Raidperet ning Jaan Toomikut

Index Scriptorium Estoniae

2007-01-01

27.05-26.08.2007 esitatakse Itaalia kunstikeskuses Pratos näitusel "Progressive Nostalgia" Jaan Toomiku videot "Merikajakas" (2004) ja Mark Raidpere videot "Andrei/Andris" (2006). Loetletud osalejad teistest maadest

[Comparison of bite marks and teeth features using 2D and 3D methods].

Science.gov (United States)

Lorkiewicz-Muszyńska, Dorota; Glapiński, Mariusz; Zaba, Czesław; Łabecka, Marzena

2011-01-01

The nature of bite marks is complex. They are found at the scene of crime on different materials and surfaces - not only on human body and corpse, but also on food products and material objects. Human bites on skin are sometimes difficult to interpret and to analyze because of the specific character of skin--elastic and distortable--and because different areas of human body have different surfaces and curvatures. A bite mark left at the scene of crime can be a highly helpful way to lead investigators to criminals. The study was performed to establish: 1) whether bite marks exhibit variations in the accuracy of impressions on different materials, 2) whether it is possible to use the 3D method in the process of identifying an individual based on the comparison of bite marks revealed at the scene, and 3D scans of dental casts, 3) whether application of the 3D method allows for elimination of secondary photographic distortion of bite marks. The authors carried out experiments on simulated cases. Five volunteers bit various materials with different surfaces. Experimental bite marks were collected with emphasis on differentiations of materials. Subsequently, dental impressions were taken from five volunteers in order to prepare five sets of dental casts (the maxilla and mandible. The biting edges of teeth were impressed in wax to create an imprint. The samples of dental casts, corresponding wax bite impressions and bite marks from different materials were scanned with 2D and 3D scanners and photographs were taken. All of these were examined in detail and then compared using different methods (2D and 3D). 1) Bite marks exhibit variations in accuracy of impression on different materials. The most legible reproduction of bite marks was seen on cheese. 2) In comparison of bite marks, the 3D method and 3D scans of dental casts are highly accurate. 3) The 3D method helps to eliminate secondary photographic distortion of bite marks.

Comparison of postoperative surgical site infection after preoperative marking done with non-sterile stationary grade markers versus sterile surgical markers

International Nuclear Information System (INIS)

Mir, Z.A.

2015-01-01

Objectives: To compare the frequencies of post- operative surgical site infection after preoperative marking done with non-sterile stationary. grade markers versus sterile surgical markers in the same patient. Design: Randomized control trial. Place and Duration of Study: The department of Plastic surgery, Mayo hospital, Lahore from August 2013 to August 2014. Methods: This study was conducted after taking approval from the departmental ethical committee. Forty consecutive patients were included. A sterile surgical marker was used to mark one incision site while an alcohol based stationary grade marker was used to mark another incision site on the same patient. A standard preoperative, intraoperative and postoperative protocol was followed. Cultures were performed on swabs taken from the incision sites and surgical site infection was assessed for 30 days. Results: The study included 40 patients; 17 males and 23 females. The mean age of subjects was 25.32 ± 19.69 years with the minimum age being 2 years and the maximum being 63 years. No growth was seen in cultures taken from all the incision sites after skin preparation in the non sterile stationary grade marker group as well as the sterile surgical grade marker group. Also no surgical site infection appeared during the 30 day postoperative observation period in the non sterile stationary grade marker group as well as the sterile surgical grade marker group. (author)

Distinguishing epigenetic marks of developmental and imprinting regulation

Directory of Open Access Journals (Sweden)

McEwen Kirsten R

2010-01-01

Full Text Available Abstract Background The field of epigenetics is developing rapidly, however we are only beginning to comprehend the complexity of its influence on gene regulation. Using genomic imprinting as a model we examine epigenetic profiles associated with different forms of gene regulation. Imprinting refers to the expression of a gene from only one of the chromosome homologues in a parental-origin-specific manner. This is dependent on heritable germline epigenetic control at a cis-acting imprinting control region that influences local epigenetic states. Epigenetic modifications associated with imprinting regulation can be compared to those associated with the more canonical developmental regulation, important for processes such as differentiation and tissue specificity. Here we test the hypothesis that these two mechanisms are associated with different histone modification enrichment patterns. Results Using high-throughput data extraction with subsequent analysis, we have found that particular histone modifications are more likely to be associated with either imprinting repression or developmental repression of imprinted genes. H3K9me3 and H4K20me3 are together enriched at imprinted genes with differentially methylated promoters and do not show a correlation with developmental regulation. H3K27me3 and H3K4me3, however, are more often associated with developmental regulation. We find that imprinted genes are subject to developmental regulation through bivalency with H3K4me3 and H3K27me3 enrichment on the same allele. Furthermore, a specific tri-mark signature comprising H3K4me3, H3K9me3 and H4K20me3 has been identified at all imprinting control regions. Conclusion A large amount of data is produced from whole-genome expression and epigenetic profiling studies of cellular material. We have shown that such publicly available data can be mined and analysed in order to generate novel findings for categories of genes or regulatory elements. Comparing two

Do olfactory behaviour and marking responses of Konik polski stallions to faeces from conspecifics of either sex differ?

Science.gov (United States)

Jezierski, Tadeusz; Jaworski, Zbigniew; Sobczyńska, Magdalena; Ensminger, John; Górecka-Bruzda, Aleksandra

2017-09-27

The aim of the study was to assess whether adult stallions differentiate their olfactory and marking behaviour towards the excreta of their potential male rivals and mares. Four Konik polski stallions were individually exposed simultaneously to their own and each others' faeces as well as faeces of mares in oestrus vs. dioestrus. Five series of 30min observation sessions were conducted in a round pen each on two consecutive days from March to July, totaling in 5h observation per stallion. Stallions sniffed and displayed flehmen reaction towards mares' faeces significantly longer (P<0.01) than towards stallions' faeces. No significant differences were found in marking by defecations upon stallions' vs. mares' faeces. The stallions urinated exclusively on mares' faeces. Sniffing, flehmen, defecations and urinations performed towards faeces of mares in oestrus vs. dioestrus did not differ significantly. The results showed that stallions differentiate their olfactory behaviour towards excreta of conspecifics of different sex but perhaps not towards faeces of females in different reproductive status. This for the first time establishes that stallions exhibit different marking behaviour upon stallions' vs. mares' faeces. It is hypothesized that marking of other stallions' faeces by defecation may advertise presence of the stallion, whereas marking of mares' faeces by urination may serve to mask the presence of a mare to prevent potential rivals from locating the mare in an area where mares' faeces are found. Copyright © 2017 Elsevier B.V. All rights reserved.

Influences of Phonological Context on Tense Marking in Spanish–English Dual Language Learners

Science.gov (United States)

Barlow, Jessica A.; Potapova, Irina; Pruitt-Lord, Sonja

2017-01-01

Purpose The emergence of tense-morpheme marking during language acquisition is highly variable, which confounds the use of tense marking as a diagnostic indicator of language impairment in linguistically diverse populations. In this study, we seek to better understand tense-marking patterns in young bilingual children by comparing phonological influences on marking of 2 word-final tense morphemes. Method In spontaneous connected speech samples from 10 Spanish–English dual language learners aged 56–66 months (M = 61.7, SD = 3.4), we examined marking rates of past tense -ed and third person singular -s morphemes in different environments, using multiple measures of phonological context. Results Both morphemes were found to exhibit notably contrastive marking patterns in some contexts. Each was most sensitive to a different combination of phonological influences in the verb stem and the following word. Conclusions These findings extend existing evidence from monolingual speakers for the influence of word-final phonological context on morpheme production to a bilingual population. Further, novel findings not yet attested in previous research support an expanded consideration of phonological context in clinical decision making and future research related to word-final morphology. PMID:28750415

Globaalne palavik ja Nord Stream / Mark Soosaar

Index Scriptorium Estoniae

Soosaar, Mark, 1946-

2009-01-01

Riigikogu keskkonnakomisjoni liikme Mark Soosaare sõnul peaks Eesti Taani eeskujul jõudma parlamentaarse otsuseni loobuda tuumajaamaehitusest, vähendada tuleks märgatavalt Eesti metsade raiumist. Vene-Saksa gaasitarneleppe vastu töötamise asemel tuleks otsida ühisosa nii Venemaa kui teiste Läänemeremaadega

77 FR 6815 - Agency Information Collection Activities: Country of Origin Marking Requirements for Containers...

Science.gov (United States)

2012-02-09

... Activities: Country of Origin Marking Requirements for Containers or Holders AGENCY: U.S. Customs and Border... information collection requirement concerning Country of Origin Marking Requirements for Containers or Holders...: Title: Country of Origin Marking Requirements for Containers or Holders. OMB Number: 1651-0057. Form...

SINGLE TREE DETECTION FROM AIRBORNE LASER SCANNING DATA USING A MARKED POINT PROCESS BASED METHOD

Directory of Open Access Journals (Sweden)

J. Zhang

2013-05-01

Full Text Available Tree detection and reconstruction is of great interest in large-scale city modelling. In this paper, we present a marked point process model to detect single trees from airborne laser scanning (ALS data. We consider single trees in ALS recovered canopy height model (CHM as a realization of point process of circles. Unlike traditional marked point process, we sample the model in a constraint configuration space by making use of image process techniques. A Gibbs energy is defined on the model, containing a data term which judge the fitness of the model with respect to the data, and prior term which incorporate the prior knowledge of object layouts. We search the optimal configuration through a steepest gradient descent algorithm. The presented hybrid framework was test on three forest plots and experiments show the effectiveness of the proposed method.

Pheochromocytoma with Markedly Abnormal Liver Function Tests and Severe Leukocytosis

Directory of Open Access Journals (Sweden)

Chai Ryoung Eun

2014-03-01

Full Text Available Pheochromocytoma is a rare neuroendocrine tumor arising from the medulla of the adrenal glands, which causes an overproduction of catecholamines. The common symptoms are headache, palpitations, and sweating; however, various other clinical manifestations might also be present. Accurate diagnosis of pheochromocytoma is important because surgical treatment is usually successful, and associated clinical problems are reversible if treated early. A 49-year-old man with a history of uncontrolled hypertension and diabetes mellitus presented with chest pain, fever, and sweating. His liver function tests and white blood cell counts were markedly increased and his echocardiography results suggested stress-induced cardiomyopathy. His abdominal computed tomography showed a 5×5-cm-sized tumor in the left adrenal gland, and laboratory tests confirmed catecholamine overproduction. After surgical resection of the left adrenal gland, his liver function tests and white blood cell counts normalized, and echocardiography showed normal cardiac function. Moreover, his previous antihypertensive regimen was deescalated, and his previously uncontrolled blood glucose levels normalized without medication.

The implement of plastic oval tags for mark-recapture in juvenile ...

African Journals Online (AJOL)

Jane

2011-10-10

Oct 10, 2011 ... 1College of Fisheries, Ocean University of China, Qingdao, 266003, PR China. 2Fishery College, Zhejiang Ocean University, .... 1; pH, 7.7 to 8.1; photoperiod, 12 L/12 D). Water was changed at a daily rate of ..... John, 2003; Robert et al., 2007). Thus, mark retention may not be a problem in marking flounder.

The interblink interval in normal and dry eye subjects

Directory of Open Access Journals (Sweden)

Johnston PR

2013-02-01

Full Text Available Patrick R Johnston,1 John Rodriguez,1 Keith J Lane,1 George Ousler,1 Mark B Abelson1,21Ora, Inc, Andover, MA, USA; 2Schepens Eye Research Institute and Harvard Medical School, Boston, MA, USAPurpose: Our aim was to extend the concept of blink patterns from average interblink interval (IBI to other aspects of the distribution of IBI. We hypothesized that this more comprehensive approach would better discriminate between normal and dry eye subjects.Methods: Blinks were captured over 10 minutes for ten normal and ten dry eye subjects while viewing a standardized televised documentary. Fifty-five blinks were analyzed for each of the 20 subjects. Means, standard deviations, and autocorrelation coefficients were calculated utilizing a single random effects model fit to all data points and a diagnostic model was subsequently fit to predict probability of a subject having dry eye based on these parameters.Results: Mean IBI was 5.97 seconds for normal versus 2.56 seconds for dry eye subjects (ratio: 2.33, P = 0.004. IBI variability was 1.56 times higher in normal subjects (P < 0.001, and the autocorrelation was 1.79 times higher in normal subjects (P = 0.044. With regard to the diagnostic power of these measures, mean IBI was the best dry eye versus normal classifier using receiver operating characteristics (0.85 area under curve (AUC, followed by the standard deviation (0.75 AUC, and lastly, the autocorrelation (0.63 AUC. All three predictors combined had an AUC of 0.89. Based on this analysis, cutoffs of ≤3.05 seconds for median IBI, and ≤0.73 for the coefficient of variation were chosen to classify dry eye subjects.Conclusion: (1 IBI was significantly shorter for dry eye patients performing a visual task compared to normals; (2 there was a greater variability of interblink intervals in normal subjects; and (3 these parameters were useful as diagnostic predictors of dry eye disease. The results of this pilot study merit investigation of IBI

Attentional Capture to a Singleton Distractor Degrades Visual Marking in Visual Search

Directory of Open Access Journals (Sweden)

Kenji Yamauchi

2017-05-01

Full Text Available Visual search is easier after observing some distractors in advance; it is as if the previewed distractors were excluded from the search. This effect is referred to as the preview benefit, and a memory template that visually marks the old locations of the distractors is thought to help in prioritizing the locations of newly presented items. One remaining question is whether the presence of a conspicuous item during the sequential shift of attention within the new items reduces this preview benefit. To address this issue, we combined the above preview search and a conventional visual search paradigm using a singleton distractor and examined whether the search performance was affected by the presence of the singleton. The results showed that the slope of reaction time as a function of set size became steeper in the presence of a singleton, indicating that the singleton distractor reduced the preview benefit. Furthermore, this degradation effect was positively correlated with the degree of conventional attentional capture to a singleton measured in a separate experiment with simultaneous search. These findings suggest that the mechanism of visual marking shares common attentional resources with the search process.

27 CFR 26.206 - Marking packages and cases.

Science.gov (United States)

2010-04-01

... Coming Into the United States From the Virgin Islands § 26.206 Marking packages and cases. The distiller... distiller, rectifier, or bottler shall plainly print, stamp, or stencil with durable coloring material, in...

ULTOR(Registered TradeMark) Passive Pose and Position Engine For Spacecraft Relative Navigation

Science.gov (United States)

Hannah, S. Joel

2008-01-01

The ULTOR(Registered TradeMark) Passive Pose and Position Engine (P3E) technology, developed by Advanced Optical Systems, Inc (AOS), uses real-time image correlation to provide relative position and pose data for spacecraft guidance, navigation, and control. Potential data sources include a wide variety of sensors, including visible and infrared cameras. ULTOR(Registered TradeMark) P3E has been demonstrated on a number of host processing platforms. NASA is integrating ULTOR(Registerd TradeMark) P3E into its Relative Navigation System (RNS), which is being developed for the upcoming Hubble Space Telescope (HST) Servicing Mission 4 (SM4). During SM4 ULTOR(Registered TradeMark) P3E will perform realtime pose and position measurements during both the approach and departure phases of the mission. This paper describes the RNS implementation of ULTOR(Registered TradeMark) P3E, and presents results from NASA's hardware-in-the-loop simulation testing against the HST mockup.

Colorectal transport during defecation in subjects with supraconal spinal cord injury

DEFF Research Database (Denmark)

Rasmussen, Mikkel Mylius; Krogh, Klaus; Clemmensen, Dorte

2013-01-01

Hospital, Denmark. Methods: Colorectal contents were marked by oral intake of 111In-coated resin pellets. Movement of stools at defecation was assessed by comparing scintigrams performed before and just after defecation. Results from 15 subjects with SCI (14 males, median age¼47 years (range: 22–74 years...... at defecation was associated with the St Mark’s fecal incontinence score (P¼0.02) but not with the Cleveland constipation score (P¼0.17), the neurogenic bowel dysfunction score (P¼0.12) or GITT (P¼0.99). Conclusion: Supraconal SCI results in significantly reduced emptying of stools at defecation...

A marked point process approach for identifying neural correlates of tics in Tourette Syndrome.

Science.gov (United States)

Loza, Carlos A; Shute, Jonathan B; Principe, Jose C; Okun, Michael S; Gunduz, Aysegul

2017-07-01

We propose a novel interpretation of local field potentials (LFP) based on a marked point process (MPP) framework that models relevant neuromodulations as shifted weighted versions of prototypical temporal patterns. Particularly, the MPP samples are categorized according to the well known oscillatory rhythms of the brain in an effort to elucidate spectrally specific behavioral correlates. The result is a transient model for LFP. We exploit data-driven techniques to fully estimate the model parameters with the added feature of exceptional temporal resolution of the resulting events. We utilize the learned features in the alpha and beta bands to assess correlations to tic events in patients with Tourette Syndrome (TS). The final results show stronger coupling between LFP recorded from the centromedian-paraficicular complex of the thalamus and the tic marks, in comparison to electrocorticogram (ECoG) recordings from the hand area of the primary motor cortex (M1) in terms of the area under the curve (AUC) of the receiver operating characteristic (ROC) curve.

Clinical and Metabolic Characterization of Lean Caucasian Subjects With Non-alcoholic Fatty Liver.

Science.gov (United States)

Feldman, Alexandra; Eder, Sebastian K; Felder, Thomas K; Kedenko, Lyudmyla; Paulweber, Bernhard; Stadlmayr, Andreas; Huber-Schönauer, Ursula; Niederseer, David; Stickel, Felix; Auer, Simon; Haschke-Becher, Elisabeth; Patsch, Wolfgang; Datz, Christian; Aigner, Elmar

2017-01-01

Non-alcoholic fatty liver disease (NAFLD) is closely linked to obesity; however, 5-8% of lean subjects also have evidence of NAFLD. We aimed to investigate clinical, genetic, metabolic and lifestyle characteristics in lean Caucasian subjects with NAFLD. Data from 187 subjects allocated to one of the three groups according to body mass index (BMI) and hepatic steatosis on ultrasound were obtained: lean healthy (BMI≤25 kg/m 2 , no steatosis, N=71), lean NAFLD (BMI≤25 kg/m 2 , steatosis, N=55), obese NAFLD (BMI≥30 kg/m 2 , steatosis; N=61). All subjects received a detailed clinical and laboratory examination including oral glucose tolerance test. The serum metabolome was assessed using the Metabolomics AbsoluteIDQ p180 kit (BIOCRATES Life Sciences). Genotyping for single-nucleotide polymorphisms (SNPs) associated with NAFLD was performed. Lean NAFLD subjects had fasting insulin concentrations similar to lean healthy subjects but had markedly impaired glucose tolerance. Lean NAFLD subjects had a higher rate of the mutant PNPLA3 CG/GG variant compared to lean controls (P=0.007). Serum adiponectin concentrations were decreased in both NAFLD groups compared to controls (Pphosphatidylcholines (PCaa C36:3; false discovery rate (FDR)-corrected P-value<0.001) as well as lysine, tyrosine, and valine (FDR<0.001). Lean subjects with evidence of NAFLD have clinically relevant impaired glucose tolerance, low adiponectin concentrations and a distinct metabolite profile with an increased rate of PNPLA3 risk allele carriage.

Age-associated increase in heterochromatic marks in murine and primate tissues.

Science.gov (United States)

Kreiling, Jill A; Tamamori-Adachi, Mimi; Sexton, Alec N; Jeyapalan, Jessie C; Munoz-Najar, Ursula; Peterson, Abigail L; Manivannan, Jayameenakshi; Rogers, Elizabeth S; Pchelintsev, Nikolay A; Adams, Peter D; Sedivy, John M

2011-04-01

Chromatin is highly dynamic and subject to extensive remodeling under many physiologic conditions. Changes in chromatin that occur during the aging process are poorly documented and understood in higher organisms, such as mammals. We developed an immunofluorescence assay to quantitatively detect, at the single cell level, changes in the nuclear content of chromatin-associated proteins. We found increased levels of the heterochromatin-associated proteins histone macro H2A (mH2A) and heterochromatin protein 1 beta (HP1β) in human fibroblasts during replicative senescence in culture, and for the first time, an age-associated increase in these heterochromatin marks in several tissues of mice and primates. Mouse lung was characterized by monophasic mH2A expression histograms at both ages, and an increase in mean staining intensity at old age. In the mouse liver, we observed increased age-associated localization of mH2A to regions of pericentromeric heterochromatin. In the skeletal muscle, we found two populations of cells with either low or high mH2A levels. This pattern of expression was similar in mouse and baboon, and showed a clear increase in the proportion of nuclei with high mH2A levels in older animals. The frequencies of cells displaying evidence of increased heterochromatinization are too high to be readily accounted for by replicative or oncogene-induced cellular senescence, and are prominently found in terminally differentiated, postmitotic tissues that are not conventionally thought to be susceptible to senescence. Our findings distinguish specific chromatin states in individual cells of mammalian tissues, and provide a foundation to investigate further the progressive epigenetic changes that occur during aging. © 2010 The Authors. Aging Cell © 2010 Blackwell Publishing Ltd/Anatomical Society of Great Britain and Ireland.

Estimates of Particulate Mass for an MCO Containing Mark 1A Fuel

International Nuclear Information System (INIS)

WYMAN, H.A.

1999-01-01

High, best estimate, and low values are given for particulate inventories within an MCO basket containing freshly cleaned Mark 1A fuel. The findings are compared with the estimates of particulate inventories for an MCO basket containing freshly cleaned Mark IV fuel

Evaluation of the single radiosensitivity in patients subjected to medical exposure that show severe skin reactions; Evaluacion de la radiosensibilidad individual en pacientes sometidos a exposiciones medicas que manifiestan reacciones cutaneas severas

Energy Technology Data Exchange (ETDEWEB)

Di Giorgio, M.; Vallerga, M.B. [Laboratorio de Dosimetria Biologica, Autoridad Regulatoria Nuclear, Av. Del Libertador 8250 (C1429BNP), Buenos Aires (Argentina); Portas, M. [Hospital de Quemados del Gobierno de la Ciudad de Buenos Aires (Argentina); Perez, M.R. [Laboratorio de Radiopatologia, Autoridad Regulatoria Nuclear, Buenos Aires (Argentina)]. e-mail: mdigiorg@cae.arn.gov.ar

2006-07-01

The Burnt Hospital of the Buenos Aires City Government (HQGCBA) it is a hospital of reference of the Net of Medical Responses in Radiological Emergencies of the Argentine Republic. In the mark of an agreement among the HQGCBA and the Authority Regulatory Nuclear (ARN), it is in execution a study protocol for the one boarding diagnoses and therapeutic of radioinduced cutaneous leisure. They exist individual variations that can condition the response to the ionizing radiations (IR), so much in accidental exposures as having programmed (radiotherapy, radiology interventionist). In this context, the individual radiosensitivity is evaluated in the patients signed up in this protocol that presented sharp or late cutaneous reactions, with grades of severity 3-4 (approaches EORTC/RTOG). The capacity of repair of the DNA was evaluated in outlying blood lymphocytes irradiated in vitro (2 Gy, gamma of Co-60) by means of the micronucleus techniques and comet essay in alkaline conditions. In this work two cases in those that is applied this study protocol, the therapeutic answer and its correlate with the discoveries of the radiosensitivity tests is presented. Case 1: patient of feminine sex, subjected to external radiotherapy by a breast infiltrating ductal carcinoma; developed sharp cutaneous radiotoxicity grade 3 (confluent humid epithelitis) that motivate the interruption of the treatment. Case 2: patient of masculine sex, subjected to a coronary angioplasty (interventionist radiology); developed late cutaneous radiotoxicity grade 4 (ulceration in dorsal region). Both patients were treated with topical trolamine associated to systemic administration of pentoxiphiline and antioxidants. The therapeutic answer is evaluated by means of clinical pursuit, photographic serial register and complementary exams (thermography and ultrasonography of high frequency). In the case 1 the answer was very favorable, with precocious local improvement and complete remission of symptoms and

7 CFR 340.7 - Marking and identity.

Science.gov (United States)

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Marking and identity. 340.7 Section 340.7 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE... identity. (a) Any regulated article to be imported other than by mail, shall, at the time of importation...

Marks & Spencer loob ELis maksupretsedenti / Sirje Rank

Index Scriptorium Estoniae

Rank, Sirje, 1966-

2005-01-01

Ilmunud ka: Delovõje Vedomosti 13. apr. lk. 6. Briti rõivakett Marks & Spencer kaebas, et Briti maksuseadused, mis ei lubanud emafirma Suurbritannias maksustavast tulust maha kanda Saksamaal, Prantsusmaal ja Belgias asunud tütarfirmade suuri kahjumeid üheksakümnendate aastate lõpus, on vastuolus EL-i ühisturu seadustega

The production of the Gospel of Mark: An essay on intertextuality ...

African Journals Online (AJOL)

For more than a century the emphasis has been on the growth and not on the making of the Gospel of Mark. This essay focuses on the latter. Firstly, attention is paid to the current views on the origins of the material in order to illustrate the implications of the traditional focus. Secondly, the production of the Gospel of Mark is ...

High prevalence of impaired glucose homeostasis and myopathy in asymptomatic and oligosymptomatic 3243A>G mitochondrial DNA mutation-positive subjects

DEFF Research Database (Denmark)

Frederiksen, A.L.; Jeppesen, T.D.; Vissing, J.

2009-01-01

combinations. Consequently, it is difficult to predict the "phenotypic risk profile" of 3243A>G mutation-positive subjects. The 3243A>G mutation coexists in cells with wild-type mtDNA, a phenomenon called heteroplasmy. The marked variability in mutation loads in different tissues is the main explanation...

Glomerular hypertrophy in subjects with low nephron number: contributions of sex, body size and race.

Science.gov (United States)

Puelles, Victor G; Douglas-Denton, Rebecca N; Zimanyi, Monika A; Armitage, James A; Hughson, Michael D; Kerr, Peter G; Bertram, John F

2014-09-01

We have shown that low nephron number (Nglom) is a strong determinant of individual glomerular volume (IGV) in male Americans. However, whether the same pattern is present in female Americans remains unclear. The contributions of body surface area (BSA) and race to IGV in the context of Nglom also require further evaluation. Kidneys without overt renal disease were collected at autopsy in Mississippi, USA. The extremes of female Nglom were used to define high and low Nglom for both sexes. Nglom and IGV were estimated by design-based stereology. A total of 24 African and Caucasian American females (n = 12 per race; 6 per Nglom extreme) were included. These subjects were subsequently matched to 24 comparable males by age and Nglom and to 18 additional males by age, Nglom and BSA. IGV average and variance were very similar in female African and Caucasian Americans with high and low Nglom. Males with low Nglom from both races showed greater IGV average and variance than comparable females matched by age and Nglom. These differences in IGV between sexes were not observed in Caucasian Americans with low Nglom that were matched by age, Nglom and BSA. In contrast, glomeruli from African Americans were larger than those from Caucasian Americans, especially in subjects with high Nglom. While female Americans with low Nglom did not show glomerular hypertrophy, comparable males with low Nglom showed marked glomerular hypertrophy that was closely associated with high BSA. Glomerular size in African Americans may be confounded by multiple additional factors. © The Author 2014. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

51. Veneetsia kunstibiennaalil esindab Eestit kunstnik Mark Raidpere...

Index Scriptorium Estoniae

2005-01-01

Mark Raidpere ekspositsiooni "Varjupaik" on koostanud Hanno Soans. 12. VI-6. XI avatud biennaalil on kaks peakuraatorit ja kaks teemanäitust: Maria de Corrali kureeritud "Kunsti kogemus" ja Rosa Martinezi kureeritud "Alati pisut eespool"

46 CFR 160.021-5 - Labeling and marking.

Science.gov (United States)

2010-10-01

...: Stand with back to wind and point away from body when igniting or flare is burning. Service Life....__). Manufactured by (Name and address of manufacturer). U.S. Coast Guard Approval No.__ (b) Marking of expiration...

Marks on the petroleum fiscality; Reperes sur la fiscalite petroliere

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-02-15

This document offers some marks on the petroleum fiscality in France: the taxes as the 'accises' and the 'TVA', the part of the taxes in the sale price at the service station, the comparison with other countries of Europe, the tax revenues and the Government budget. It provides also marks on the fuels prices formation (margins), the world petroleum markets (supply and demand) and the part of the petroleum companies on the petroleum market. (A.L.B.)

Eliciting Subjective Probabilities with Binary Lotteries

DEFF Research Database (Denmark)

Harrison, Glenn W.; Martínez-Correa, Jimmy; Swarthout, J. Todd

objective probabilities. Drawing a sample from the same subject population, we find evidence that the binary lottery procedure induces linear utility in a subjective probability elicitation task using the Quadratic Scoring Rule. We also show that the binary lottery procedure can induce direct revelation...

Casting traceability with direct part marking using reconfigurable pin-type tooling based on paraffin–graphite actuators

DEFF Research Database (Denmark)

Vedel-Smith, Nikolaj Kjelgaard; Lenau, Torben Anker

2012-01-01

Green sand moulding machines for cast iron foundries are presently unable to uniquely identify individual castings. An insert tool concept is developed and tested via incremental mock-up development. The tool is part of the pattern plate and changes shape between each moulding, thus giving each...... mould a unique ID by embossing a Data Matrix symbol into the sand. In the process of producing the mould, each casting can be given a unique (DPM), enabling part tracking throughout the casting's life cycle. Sand embossing is achieved with paraffin-actuated reconfigurable pin-type tooling under...... simulated processing conditions. The marker geometry limitations have been tested using static symbol patterns, both for sand embossing and actual casting marking. The marked castings have successfully been identified with decoding software. The study shows that the function of each element...

48 CFR 252.227-7037 - Validation of restrictive markings on technical data.

Science.gov (United States)

2010-10-01

.... However, this clause neither creates nor implies privity of contract between the Government and... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.227-7037 Validation of restrictive markings on... following clause: Validation of Restrictive Markings on Technical Data (SEP 1999) (a) Definitions. The terms...

A geometric stochastic approach based on marked point processes for road mark detection from high resolution aerial images

Science.gov (United States)

Tournaire, O.; Paparoditis, N.

Road detection has been a topic of great interest in the photogrammetric and remote sensing communities since the end of the 70s. Many approaches dealing with various sensor resolutions, the nature of the scene or the wished accuracy of the extracted objects have been presented. This topic remains challenging today as the need for accurate and up-to-date data is becoming more and more important. Based on this context, we will study in this paper the road network from a particular point of view, focusing on road marks, and in particular dashed lines. Indeed, they are very useful clues, for evidence of a road, but also for tasks of a higher level. For instance, they can be used to enhance quality and to improve road databases. It is also possible to delineate the different circulation lanes, their width and functionality (speed limit, special lanes for buses or bicycles...). In this paper, we propose a new robust and accurate top-down approach for dashed line detection based on stochastic geometry. Our approach is automatic in the sense that no intervention from a human operator is necessary to initialise the algorithm or to track errors during the process. The core of our approach relies on defining geometric, radiometric and relational models for dashed lines objects. The model also has to deal with the interactions between the different objects making up a line, meaning that it introduces external knowledge taken from specifications. Our strategy is based on a stochastic method, and in particular marked point processes. Our goal is to find the objects configuration minimising an energy function made-up of a data attachment term measuring the consistency of the image with respect to the objects and a regularising term managing the relationship between neighbouring objects. To sample the energy function, we use Green algorithm's; coupled with a simulated annealing to find its minimum. Results from aerial images at various resolutions are presented showing that our

Colour marking of transparent materials by laser-induced plasma-assisted ablation (LIPAA)

International Nuclear Information System (INIS)

Hanada, Yasutaka; Sugioka, Koji; Miyamoto, Iwao; Midorikawa, Katsumi

2007-01-01

We demonstrate colour marking of a transparent material using laser-induced plasma-assisted ablation (LIPAA) system. After the LIPAA process, metal thin film is deposited on the surface of the ablated groove. This feature is applied to RGB (red, green and blue) colour marking by using specific metal targets. The metal targets, for instance, are Pb 3 O 4 for red, Cr 2 O 3 for green and [Cu(C 32 H 15 ClN 8 )] for blue colour marking. Additionally, adhesion of the metal thin film deposited on the processed groove by various experimental conditions is investigated

RAPID INSPECTION OF PAVEMENT MARKINGS USING MOBILE LIDAR POINT CLOUDS

Directory of Open Access Journals (Sweden)

H. Zhang

2016-06-01

Full Text Available This study aims at building a robust semi-automated pavement marking extraction workflow based on the use of mobile LiDAR point clouds. The proposed workflow consists of three components: preprocessing, extraction, and classification. In preprocessing, the mobile LiDAR point clouds are converted into the radiometrically corrected intensity imagery of the road surface. Then the pavement markings are automatically extracted with the intensity using a set of algorithms, including Otsu’s thresholding, neighbor-counting filtering, and region growing. Finally, the extracted pavement markings are classified with the geometric parameters using a manually defined decision tree. Case studies are conducted using the mobile LiDAR dataset acquired in Xiamen (Fujian, China with different road environments by the RIEGL VMX-450 system. The results demonstrated that the proposed workflow and our software tool can achieve 93% in completeness, 95% in correctness, and 94% in F-score when using Xiamen dataset.

FDA, CE mark or something else?-Thinking fast and slow.

Science.gov (United States)

Mishra, Sundeep

There is a robust debate going on among the Medical Device stake-holders whether FDA is better or CE mark or something else. Currently process of obtaining an FDA approval is bogged down by ever-increasing unpredictability, inconsistency, prolonged time, and huge expense but CE mark has its own problems. Historically, the Japanese review process has tended to be the slowest among the big three but recently with the introduction of accelerated review process there has been a significant progress. While the goal of an innovator/manufacturer is to develop, manufacture and market a medical device that addresses an unmet clinical need, the requisite regulatory approval process can be very confusing. Not only there is a whole lot of jargon tossed around by regulatory affair professionals: "substantial equivalence," "PMDA," "CE mark," "Notified body," "510K" and "PMA" but the actual approval process can also be very tardy, inconsistent and expensive. Copyright © 2016 Cardiological Society of India. Published by Elsevier B.V. All rights reserved.

46 CFR 160.037-5 - Labeling and marking.

Science.gov (United States)

2010-10-01

.... Caution: Stand with back to wind and point away from body when igniting or signal is burning. Service Life.... __). Manufactured by (Name and address of manufacturer). U.S. Coast Guard Approval No. __. (b) Marking of expiration...

Neuro-diffuse algorithm for neutronic power identification of TRIGA Mark III reactor; Algoritmo neuro-difuso para la identificacion de la potencia neutronica del reactor Triga Mark III

Energy Technology Data Exchange (ETDEWEB)

Rojas R, E.; Benitez R, J. S. [Instituto Tecnologico de Toluca, Division de Estudios de Posgrado e Investigacion, Av. Tecnologico s/n, Ex-Rancho La Virgen, 50140 Metepec, Estado de Mexico (Mexico); Segovia de los Rios, J. A.; Rivero G, T. [ININ, Gerencia de Ciencias Aplicadas, Carretera Mexico-Toluca s/n, 52750 Ocoyoacac, Estado de Mexico (Mexico)], e-mail: jorge.benitez@inin.gob.mx

2009-10-15

In this work are presented the results of design and implementation of an algorithm based on diffuse logic systems and neural networks like method of neutronic power identification of TRIGA Mark III reactor. This algorithm uses the punctual kinetics equation as data generator of training, a cost function and a learning stage based on the descending gradient algorithm allow to optimize the parameters of membership functions of a diffuse system. Also, a series of criteria like part of the initial conditions of training algorithm are established. These criteria according to the carried out simulations show a quick convergence of neutronic power estimated from the first iterations. (Author)

9 CFR 310.5 - Condemned carcasses and parts to be so marked; tanking; separation.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Condemned carcasses and parts to be so marked; tanking; separation. 310.5 Section 310.5 Animals and Animal Products FOOD SAFETY AND INSPECTION... marked shall be placed immediately in trucks or receptacles which shall be kept plainly marked “U.S...

Analysis of ancient Indian silver punch-marked coins by external PIXE

International Nuclear Information System (INIS)

Rautray, Tapash R.; Nayak, Suman S.; Tripathy, Bipin B.; Das, Saubhagyalaxmi; Das, Manas R.; Das, Satya R.; Chattopadhyay, Pranab K.

2011-01-01

Seven silver punch-marked coins were analysed using external particle induced X-ray emission technique. The main group of elements like Ag, Cu, Au, Pb and Fe were estimated along with a number of trace/minor elements such as K, Ca, Ti, V, Cr, Mn, Co, Ni and Rb in the analysed silver coins. Gold was found in all the coins and varied between 0.7% and 6.2% indicating the better economic condition of that civilisation. - Highlights: → The silver punch-marked coins, in the current study, were in use in India between 6th century BC to 6th century AD and have been analysed by in-air PIXE. → These sets of coins have immense archaeological importance because of their very rare availability. → These coins are distinguished from other coins because of the presence of gold as major element. → While the British period coins were fabricated using modern technologies, the punch-marked coins were shaped manually with developed metal technology. → The analysis of punch-marked coins using external PIXE beam has been done for the first time, which is unique of its kind.

histone H3 predominantly mark the pericentromeric chromatin

Indian Academy of Sciences (India)

SANTOSH KUMAR SHARMA

packaging of eukaryotic DNA in nucleoprotein complex known as .... The plant material used in the present study has ... materials (root tips/flower buds) were fixed in PHEMES ..... fications that mark active chromatin, while there are no data.

Characterization of the TRIGA Mark II reactor full-power steady state

Energy Technology Data Exchange (ETDEWEB)

Cammi, Antonio, E-mail: antonio.cammi@polimi.it [Politecnico di Milano – Department of Energy, CeSNEF (Enrico Fermi Center for Nuclear Studies), via La Masa 34, 20156 Milano (Italy); Zanetti, Matteo [Politecnico di Milano – Department of Energy, CeSNEF (Enrico Fermi Center for Nuclear Studies), via La Masa 34, 20156 Milano (Italy); Chiesa, Davide; Clemenza, Massimiliano; Pozzi, Stefano; Previtali, Ezio; Sisti, Monica [University of Milano-Bicocca, Physics Department “G. Occhialini” and INFN Section, Piazza dell’Ateneo Nuovo, 20126 Milan (Italy); Magrotti, Giovanni; Prata, Michele; Salvini, Andrea [University of Pavia, Applied Nuclear Energy Laboratory (L.E.N.A.), Via Gaspare Aselli 41, 27100 Pavia (Italy)

2016-04-15

Highlights: • Full-power steady state characterization of the TRIGA Mark II reactor. • Monte Carlo and Multiphysics simulation of the TRIGA Mark II reactor. • Sub-cooled boiling effects in the TRIGA Mark II reactor. • Thermal feedback effects in the TRIGA Mark II reactor. • Experimental data based validation. - Abstract: In this paper, the characterization of the full-power steady state of the TRIGA Mark II nuclear reactor at the University of Pavia is achieved by coupling the Monte Carlo (MC) simulation for neutronics with the “Multiphysics” model for thermal-hydraulics. Neutronic analyses have been carried out with a MCNP5 based MC model of the entire reactor system, already validated in fresh fuel and zero-power configurations (in which thermal effects are negligible) and using all available experimental data as a benchmark. In order to describe the full-power reactor configuration, the temperature distribution in the core must be established. To evaluate this, a thermal-hydraulic model has been developed, using the power distribution results from the MC simulation as input. The thermal-hydraulic model is focused on the core active region and takes into account sub-cooled boiling effects present at full reactor power. The obtained temperature distribution is then entered into the MC model and a benchmark analysis is carried out to validate the model in fresh fuel and full-power configurations. An acceptable correspondence between experimental data and simulation results concerning full-power reactor criticality proves the reliability of the adopted methodology of analysis, both from the perspective of neutronics and thermal-hydraulics.

The Mark III vertex chamber

International Nuclear Information System (INIS)

Adler, J.; Bolton, T.; Bunnell, K.

1987-07-01

The design and construction of the new Mark III vertex chamber is described. Initial tests with cosmic rays prove the ability of track reconstruction and yield triplet resolutions below 50 μm at 3 atm using argon/ethane (50:50). Also performed are studies using a prototype of a pressurized wire vertex chamber with 8 mm diameter straw geometry. Spatial resolution of 35mm was obtained using dimethyl ether (DME) at 1 atm and 30 μm using argon/ethane (50/50 mixture) at 4 atm. Preliminary studies indicate the DME to adversely affect such materials as aluminized Mylar and Delrin

Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors

Energy Technology Data Exchange (ETDEWEB)

Katz, Jason D.; Haidle, Andrew; Childers, Kaleen K.; Zabierek, Anna A.; Jewell, James P.; Hou, Yongquan; Altman, Michael D.; Szewczak, Alexander; Chen, Dapeng; Harsch, Andreas; Hayashi, Mansuo; Warren, Lee; Hutton, Michael; Nuthall, Hugh; Su, Hua-Poo; Munshi, Sanjeev; Stanton, Matt G.; Davies, Ian W.; Munoz, Ben; Northrup, Alan (Merck)

2017-01-01

The initial structure activity relationships around an isoindoline uHTS hit will be described. Information gleaned from ligand co-crystal structures allowed for rapid refinements in both MARK potency and kinase selectivity. These efforts allowed for the identification of a compound with properties suitable for use as an in vitro tool compound for validation studies on MARK as a viable target for Alzheimer’s disease.

Subjective difficulties in young people related to extensive loud music listening

Directory of Open Access Journals (Sweden)

Budimčić Milenko

2010-01-01

Full Text Available Introduction. For human ear, noise represents every undesirable and valueless sound. In disco clubs, as in some other places with loud music mostly attended by young people, the level of noise sometimes attains over 100 dB. As reported by numerous studies, a high noise level could induce subjective difficulties (ear buzzing, audition loss, vertigo and palpitations, anxiety, high blood pressure, decreased concentration, lowered memory storing. Objective. Assessment of subjective difficulties occurring in young people when staying in places with a high noise level (cafes, disco clubs, rock concerts, which can produce health problems, due to loud music, in association with demographic data, addictions and personal life style data. One of the goals is to find factors leading to subjective difficulties, which would be objectively studied in the second stage of the research and marked as early predictors of possible health problems. Methods. The study was conducted among 780 students of the Higher Healthcare School of Professional Studied in Belgrade. We used a questionnaire with 20 questions, divided into four categories: demographic data, case-history data, subjective problems and addictions of the subjects. In the statistical data processing we used the methods of descriptive and exploratory analysis, chi-square tests, correlation tests and Mantel-Haenszel odds ratio. Results. After listening loud music, 54.0% of examined subjects felt ear buzzing, and 4.6% had hearing damage. The habit of visiting places with loud music, mostly once a week in duration of 2-3 hours per visit had 80.4% of subjects. The presence of subjective complaints after listening of loud music was in association with loud music listening and disco clubs visits. The major reasons of the present subjective difficulties could be predicated by listening of loud music and club visits (r=0.918 and r=0.857. A relative risk for subjective difficulties presentation was 1.599. Conclusion