WorldWideScience

Sample records for subject matter standards

  1. Teaching Evolution: Do State Standards Matter?

    Science.gov (United States)

    Moore, Randy

    2002-01-01

    Explores the relationship of state standards for the teaching of evolution to the actual teaching of that subject. Compares a grading of states for their performance and discusses the question of whether state standards matter. (MM)

  2. Changes in Dictionary Subject Matter

    DEFF Research Database (Denmark)

    Nielsen, Sandro

    2003-01-01

    The general content of the three editions of the Duden dictionary has undergone few changes. The most substantial changes are the addition of syllabification and the deletion of antonomy in respect of lemmata in the second and third editions. The concept of dictionary subject matter is questioned...

  3. Foodservice. Subject Matter Update 1986-87.

    Science.gov (United States)

    Oregon State Dept. of Education, Salem. Div. of Vocational Education.

    This publication recognizes the constantly changing requirements of the food service industry and varying conditions for employment opportunities. It addresses the goal of relevance in education by enabling the educator to make timely adjustments in the subject matter of the food service curriculum. There are six sections in this publication, each…

  4. 45 CFR 703.3 - Scope of subject matter.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Scope of subject matter. 703.3 Section 703.3... AND FUNCTIONS OF STATE ADVISORY COMMITTEES § 703.3 Scope of subject matter. The scope of the subject matter to be dealt with by Advisory Committees shall be those subjects of inquiry or study with which the...

  5. Dark matter interaction between massive standard particles

    OpenAIRE

    Renard, Fernand M

    2018-01-01

    We propose further tests of the assumption that the mass of the heavy standard particles ($Z,W,t,...$) arises from a special coupling with dark matter. We look for effects of new interactions due to dark matter exchanges between heavy particles in several $e^+e^-$ and hadronic collision processes.

  6. 49 CFR 1108.3 - Matters subject to arbitration.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Matters subject to arbitration. 1108.3 Section... BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE ARBITRATION OF CERTAIN DISPUTES SUBJECT TO THE STATUTORY JURISDICTION OF THE SURFACE TRANSPORTATION BOARD § 1108.3 Matters subject to arbitration. (a) Any...

  7. Single-subject grey matter graphs in Alzheimer's disease.

    Science.gov (United States)

    Tijms, Betty M; Möller, Christiane; Vrenken, Hugo; Wink, Alle Meije; de Haan, Willem; van der Flier, Wiesje M; Stam, Cornelis J; Scheltens, Philip; Barkhof, Frederik

    2013-01-01

    Coordinated patterns of cortical morphology have been described as structural graphs and previous research has demonstrated that properties of such graphs are altered in Alzheimer's disease (AD). However, it remains unknown how these alterations are related to cognitive deficits in individuals, as such graphs are restricted to group-level analysis. In the present study we investigated this question in single-subject grey matter networks. This new method extracts large-scale structural graphs where nodes represent small cortical regions that are connected by edges when they show statistical similarity. Using this method, unweighted and undirected networks were extracted from T1 weighted structural magnetic resonance imaging scans of 38 AD patients (19 female, average age 72±4 years) and 38 controls (19 females, average age 72±4 years). Group comparisons of standard graph properties were performed after correcting for grey matter volumetric measurements and were correlated to scores of general cognitive functioning. AD networks were characterised by a more random topology as indicated by a decreased small world coefficient (p = 3.53×10(-5)), decreased normalized clustering coefficient (p = 7.25×10(-6)) and decreased normalized path length (p = 1.91×10(-7)). Reduced normalized path length explained significantly (p = 0.004) more variance in measurements of general cognitive decline (32%) in comparison to volumetric measurements (9%). Altered path length of the parahippocampal gyrus, hippocampus, fusiform gyrus and precuneus showed the strongest relationship with cognitive decline. The present results suggest that single-subject grey matter graphs provide a concise quantification of cortical structure that has clinical value, which might be of particular importance for disease prognosis. These findings contribute to a better understanding of structural alterations and cognitive dysfunction in AD.

  8. Conditioning audience patronage using subject matters in ...

    African Journals Online (AJOL)

    Films are subject-based and when producers set out to communicate their viewpoints, some do it flamboyantly while others take the subtle path. Unlike live theatre before it, the possibility of a virile spiral regarding the themes treated in movies can be as much repugnant as they can be fascinating. In this case, the audience ...

  9. 40 CFR 60.732 - Standards for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standards for particulate matter. 60... Dryers in Mineral Industries § 60.732 Standards for particulate matter. Each owner or operator of any... particulate matter in excess of 0.092 gram per dry standard cubic meter (g/dscm) for calciners and for...

  10. 40 CFR 60.382 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.382... Processing Plants § 60.382 Standard for particulate matter. (a) On and after the date on which the... stack emissions that: (1) Contain particulate matter in excess of 0.05 grams per dry standard cubic...

  11. Cortex Parcellation Associated Whole White Matter Parcellation in Individual Subjects

    Directory of Open Access Journals (Sweden)

    Patrick Schiffler

    2017-07-01

    Full Text Available The investigation of specific white matter areas is a growing field in neurological research and is typically achieved through the use of atlases. However, the definition of anatomically based regions remains challenging for the white matter and thus hinders region-specific analysis in individual subjects. In this article, we focus on creating a whole white matter parcellation method for individual subjects where these areas can be associated to cortex regions. This is done by combining cortex parcellation and fiber tracking data. By tracking fibers out of each cortex region and labeling the fibers according to their origin, we populate a candidate image. We then derive the white matter parcellation by classifying each white matter voxel according to the distribution of labels in the corresponding voxel from the candidate image. The parcellation of the white matter with the presented method is highly reliable and is not as dependent on registration as with white matter atlases. This method allows for the parcellation of the whole white matter into individual cortex region associated areas and, therefore, associates white matter alterations to cortex regions. In addition, we compare the results from the presented method to existing atlases. The areas generated by the presented method are not as sharply defined as the areas in most existing atlases; however, they are computed directly in the DWI space of the subject and, therefore, do not suffer from distortion caused by registration. The presented approach might be a promising tool for clinical and basic research to investigate modalities or system specific micro structural alterations of white matter areas in a quantitative manner.

  12. 40 CFR 60.292 - Standards for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standards for particulate matter. 60... Manufacturing Plants § 60.292 Standards for particulate matter. (a) On and after the date on which the..., particulate matter at emission rates exceeding those specified in table CC-1, Column 2 and Column 3...

  13. 40 CFR 60.532 - Standards for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standards for particulate matter. 60... Wood Heaters § 60.532 Standards for particulate matter. Unless exempted under § 60.530, each affected... comply with the following particulate matter emission limits as determined by the test methods and...

  14. 40 CFR 60.472 - Standards for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standards for particulate matter. 60... Processing and Asphalt Roofing Manufacture § 60.472 Standards for particulate matter. (a) On and after the...) Particulate matter in excess of: (i) 0.04 kg/Mg (0.08 lb/ton) of asphalt shingle or mineral-surfaced roll...

  15. 40 CFR 60.422 - Standards for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standards for particulate matter. 60... Manufacture § 60.422 Standards for particulate matter. On or after the date on which the performance test... sulfate dryer, particulate matter at an emission rate exceeding 0.15 kilogram of particulate per megagram...

  16. 40 CFR 60.272a - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60... Standard for particulate matter. (a) On and after the date of which the performance test required to be... control device and contain particulate matter in excess of 12 mg/dscm (0.0052 gr/dscf); (2) Exit from a...

  17. 40 CFR 60.262 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.262... Production Facilities § 60.262 Standard for particulate matter. (a) On and after the date on which the... furnace any gases which: (1) Exit from a control device and contain particulate matter in excess of 0.45...

  18. 40 CFR 60.172 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.172... Smelters § 60.172 Standard for particulate matter. (a) On and after the date on which the performance test... contain particulate matter in excess of 50 mg/dscm (0.022 gr/dscf). ...

  19. 40 CFR 60.122 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.122... Smelters § 60.122 Standard for particulate matter. (a) On and after the date on which the performance test... furnace any gases which: (1) Contain particulate matter in excess of 50 mg/dscm (0.022 gr/dscf). (2...

  20. 40 CFR 60.92 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.92... Facilities § 60.92 Standard for particulate matter. (a) On and after the date on which the performance test... which: (1) Contain particulate matter in excess of 90 mg/dscm (0.04 gr/dscf). (2) Exhibit 20 percent...

  1. 40 CFR 60.142 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.142....142 Standard for particulate matter. (a) Except as provided under paragraph (b) of this section, on... the atmosphere from any affected facility any gases which: (1) Contain particulate matter in excess of...

  2. 40 CFR 60.182 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.182... Smelters § 60.182 Standard for particulate matter. (a) On and after the date on which the performance test... furnace, or sintering machine discharge end any gases which contain particulate matter in excess of 50 mg...

  3. 40 CFR 60.302 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.302... § 60.302 Standard for particulate matter. (a) On and after the 60th day of achieving the maximum... a grain dryer any process emission which: (1) Contains particulate matter in excess of 0.023 g/dscm...

  4. 40 CFR 60.132 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.132... and Bronze Production Plants § 60.132 Standard for particulate matter. (a) On and after the date on... reverberatory furnace any gases which: (1) Contain particulate matter in excess of 50 mg/dscm (0.022 gr/dscf...

  5. 40 CFR 60.272 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.272... Standard for particulate matter. (a) On and after the date on which the performance test required to be... control device and contain particulate matter in excess of 12 mg/dscm (0.0052 gr/dscf). (2) Exit from a...

  6. 40 CFR 60.402 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.402... Plants § 60.402 Standard for particulate matter. (a) On and after the date on which the performance test... which: (i) Contain particulate matter in excess of 0.030 kilogram per megagram of phosphate rock feed (0...

  7. 40 CFR 60.342 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.342... Manufacturing Plants § 60.342 Standard for particulate matter. (a) On and after the date on which the... gases which: (1) Contain particulate matter in excess of 0.30 kilogram per megagram (0.60 lb/ton) of...

  8. 40 CFR 60.162 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.162... Smelters § 60.162 Standard for particulate matter. (a) On and after the date on which the performance test... particulate matter in excess of 50 mg/dscm (0.022 gr/dscf). ...

  9. 40 CFR 60.282 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.282... § 60.282 Standard for particulate matter. (a) On and after the date on which the performance test...: (i) Contain particulate matter in excess of 0.10 g/dscm (0.044 gr/dscf) corrected to 8 percent oxygen...

  10. 40 CFR 60.52 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.52... § 60.52 Standard for particulate matter. (a) On and after the date on which the initial performance... atmosphere from any affected facility any gases which contain particulate matter in excess of 0.18 g/dscm (0...

  11. 40 CFR 60.682 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standard of Performance for Wool Fiberglass Insulation Manufacturing Plants § 60.682 Standard for particulate matter. On and after the date on which the...

  12. 22 CFR 61.6 - Consultation with subject matter specialists.

    Science.gov (United States)

    2010-04-01

    ... FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.6 Consultation with subject matter specialists. (a) The... assisting the Department in its determination of whether materials for which export certification or import... determine eligibility of material for certification or authentication based in part on the opinions obtained...

  13. students' perception of teacher's knowledge of subject matter and ...

    African Journals Online (AJOL)

    ALEXANDER E. TIMOTHY

    The study used the ex post facto design to find out the influence of student's perception of teacher's knowledge of the subject matter on the Senior Secondary Three (SS 3) students' performance in reading comprehension. Questionnaires reading comprehension test were used in eliciting data. The data were subsequently ...

  14. Does tutor subject-matter expertise influence student achievement in ...

    African Journals Online (AJOL)

    Objective. To establish whether or not tutor subject-matter expertise influences student achievement in content-based examinations in the problem-based learning (PBL) curriculum at the University of Transkei (UNITRA) Medical School. Design. A retrospective study of MB ChB III student achievement in end-of-block ...

  15. Teachers mathematical communication profile in explaining subject matter

    Science.gov (United States)

    Umami, Rohmatul; Budayasa, I. Ketut; Suwarsono, St.

    2017-12-01

    This study aimed to see a teachers mathematical communication profile in explaining a subject matter. It is a qualitative research. A high-school junior teacher (i.e., a teacher with 1- to 5-year experience) teaching mathematics at X-Social Class was selected as the subject of this study. The data was collected by observing the teachers mathematical communication in explaining a given material (i.e., the rule of sine) in class and an in-depth interview would be organized respectively. The result showed that the junior teacher explained the subject matter in systematic, complete, fluent, and centered manner. In this case, she began with reminding students on the previous material related to the current material to be learned, informing the current learning objectives, and finally delivering the subject matter. To support her explanation, the teacher also provided some related information, led the students attention into the given material by asking them particular related questions, and did not use any confusing terms. However, the study found that some of high-school teachers still used less appropriate language in explaining materials.

  16. 40 CFR 60.62 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.62... Plants § 60.62 Standard for particulate matter. (a) On and after the date on which the performance test... particulate matter in excess of 0.15 kg per metric ton of feed (dry basis) to the kiln (0.30 lb per ton). (2...

  17. 40 CFR 60.152 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for particulate matter. 60.152... Plants § 60.152 Standard for particulate matter. (a) On and after the date on which the performance test...: (1) Particulate matter at a rate in excess of 0.65 g/kg dry sludge input (1.30 lb/ton dry sludge...

  18. Engaging Students with Subject Matter Experts and Science Content Through Classroom Connection Webinars

    Science.gov (United States)

    Graff, P. V.; Rampe, E.; Stefanov, W. L.; Vanderbloemen, L.; Higgins, M.

    2015-01-01

    Connecting students and teachers in classrooms with science, technology, engineering, and mathematics (STEM) experts provides an invaluable opportunity. Subject matter experts can share exciting science and science-related events as well as help to "translate" science being conducted by professionals. The Expedition Earth and Beyond (EEAB) Program, facilitated by the Astromaterials Research and Exploration Science (ARES) Division at the NASA Johnson Space Center, has been providing virtual access to subject matter experts through classroom connection webinars for the last five years. Each year, the reach of these events has grown considerably, especially over the last nine months. These virtual connections not only help engage students with role models, but are also designed to help teachers address concepts and content standards they are required to teach. These events also enable scientists and subject matter experts to help "translate" current science in an engaging and understandable manner while actively involving classrooms in the journey of science and exploration.

  19. 106-17 Telemetry Standards Front Matter

    Science.gov (United States)

    2017-07-01

    prepared this document to foster the compatibility of telemetry transmitting, receiving, and signal processing equipment at the member ranges under the...Frequency Division Multiplexing Telemetry Standards CHAPTER 4: Pulse Code Modulation Standards CHAPTER 5: Digitized Audio Telemetry Standard CHAPTER 6...Recorder & Reproducer Command and Control CHAPTER 7: Packet Telemetry Downlink CHAPTER 8: Digital Data Bus Acquisition Formatting Standard CHAPTER

  20. Dark matter, constrained minimal supersymmetric standard model, and lattice QCD.

    Science.gov (United States)

    Giedt, Joel; Thomas, Anthony W; Young, Ross D

    2009-11-13

    Recent lattice measurements have given accurate estimates of the quark condensates in the proton. We use these results to significantly improve the dark matter predictions in benchmark models within the constrained minimal supersymmetric standard model. The predicted spin-independent cross sections are at least an order of magnitude smaller than previously suggested and our results have significant consequences for dark matter searches.

  1. Smart Start II: Why Standards Matter.

    Science.gov (United States)

    Barth, Patte; Mitchell, Ruth

    This book explores how standards are bringing about changes in elementary schools and conveys what standards-based education in elementary schools looks and feels like. Chapter 1 tells the story of Andrew as an emblem of the common fate of children in an educational system that did not know its purpose. Chapter 2 sketches the history and…

  2. Learning, knowledge building, and subject matter knowledge in school science

    Science.gov (United States)

    van Aalst, Jan Cornelis Wouterus

    Following a theoretical analysis of constructivist approaches to collaborative learning, a curriculum development model, the Learning to Knowledge Building Model, is proposed. Two empirical studies of student work with Computer Supported Intentional Learning Environment (CSILE) are then presented; these lend support to the model and explicate in detail the nature and extent of the knowledge developed by elementary school students. The first study is a content analysis of a database developed by a combined Grade 5/6 class as part of a unit on heat and matter, conducted after the children completed their work; the analysis assumes the point of view of a subject matter specialist in the field of the students' inquiry. The second study was conducted while the students' investigation was in progress, and takes the point of view of curriculum coverage; it involved a teacher who used a different model of database use, as well as different subject matter. The proposed LKB model is based on a distinction Bereiter and Scardamalia (1996a) have made between learning and knowledge building (i.e., progressive collaborative problem solving); its aim is to support the design and planning of curriculum units and classroom practices in which knowledge building is central. An important feature of the model is the attention given to ensuring that students learn to evaluate their knowledge and to ask the questions that can advance shared knowledge. Among the findings of the first study are: (a) students who wrote more notes that explicated their commonsense knowledge early in the unit, by means of mixed framework notes, tended to write more notes of high scientific merit later; (b) some of the students in this category tried out their ideas in diverse problem contexts; and (c) they tended to dominate the discussions they started. The second study provides additional insight into the role of the teacher, and the potential role of subject matter specialists, in knowledge building; it

  3. A "post-psychological" curiosity of subjectivities and standards

    DEFF Research Database (Denmark)

    Nissen, Morten; Staunæs, Dorthe; Bank, Mads

    2016-01-01

    a division between standardizing sciences and off-standard qualitative research. Yet, a “postpsychological curiosity” suggests a reflexive stance, admitting to complicity in the “intra-actions” of standards and subjectivity, in theoretical psychology as in practices such as management, counseling, or self...

  4. Landscape History and Theory: from Subject Matter to Analytical Tool

    Directory of Open Access Journals (Sweden)

    Jan Birksted

    2003-10-01

    Full Text Available This essay explores how landscape history can engage methodologically with the adjacent disciplines of art history and visual/cultural studies. Central to the methodological problem is the mapping of the beholder - spatially, temporally and phenomenologically. In this mapping process, landscape history is transformed from subject matter to analytical tool. As a result, landscape history no longer simply imports and applies ideas from other disciplines but develops its own methodologies to engage and influence them. Landscape history, like art history, thereby takes on a creative cultural presence. Through that process, landscape architecture and garden design regains the cultural power now carried by the arts and museum studies, and has an effect on the innovative capabilities of contemporary landscape design.

  5. Journeys Beyond the Standard Model: Supersymmetry and Dark Matter

    Science.gov (United States)

    Goodman, Jessica L.

    This thesis attempts to address two outstanding issues in the Standard Model of particle physics. The first of these two has to do with the lack of a viable dark matter candidate in the Standard Model. Many recent experimental results hint at the possibility of a light dark matter particle. If it is light enough, one may consider producing these particles at colliders. Parts of this thesis considers effective theories of dark matter as a way to develop a language to compare collider searches for dark matter to direct and indirect detection experiments. The second of these two issues explores the more aesthetic problem of the gauge hierarchy through construction of supersymmetry breaking models. In the first set of models, we construct UV completions of O'Raifeartaigh-like models which spontaneously break R symmetry. In the final chapter, we construct a R symmetric GMSB model in which we use Seiberg dynamics to generate supersoft Dirac gaugino masses.

  6. The interrelationship between subject matter and school gardens

    DEFF Research Database (Denmark)

    Christensen, Jacob Højgaard; Wistoft, Karen

    2018-01-01

    This article maps out existing research regarding the effectiveness of integrated teaching in school gardens, i.e. including the math, languages and science subjects with their related objectives and curricula in school garden teaching and vice versa. The article is based on a literature review...... a standard garden curriculum is essential to planning, carrying out and evaluating effective school garden teaching in math, languages and science. Experiential learning and hands-on activities are teaching methods that immediately come to mind because they make the subject content less abstract, activate...... that concludes that school gardens have a predominantly positive influence on students’ learning outcome. However, there are a few school garden programmes that have the same or even a less beneficial influence on students’ learning outcome than traditional teaching. Thus, school gardens do not have...

  7. 40 CFR 60.102 - Standard for particulate matter.

    Science.gov (United States)

    2010-07-01

    ... Refineries § 60.102 Standard for particulate matter. Each owner or operator of any fluid catalytic cracking... which the fluid catalytic cracking unit catalyst regenerator will be operated, or 180 days after initial... discharge or cause the discharge into the atmosphere from any fluid catalytic cracking unit catalyst...

  8. On indexes and subject matter of “global competitiveness”

    Directory of Open Access Journals (Sweden)

    A. V. Korotkov

    2017-01-01

    Full Text Available The aim of the research is to analyze the subject matter of a country’s competitiveness and to characterize statistical indexes of competitiveness known in the international practice from the perspective of a more elaborated theory of market competition. This aim follows from the identified problems. First, there are no generally accepted interpretation and joint understanding of competition and competitiveness at country level. Even the international organizations giving estimations of global competitiveness disagree on definitions of competitiveness. Secondly, there is no relation to the theory of market competition in the available source materials on competitiveness of the country without original methodology. Thirdly, well-known statistical indexes of global competitiveness do not have enough theoretical justification and differ in sets of factors. All this highlights the incompleteness of the methodology and methodological support of studying competitiveness at country level.Materials and methods. The research is based on the methodology of statistics, economic theory and marketing. The authors followed the basic principle of statistical methodology – requirement of continuous combination of qualitative and quantitative analysis, when the research begins and ends with qualitative analysis. A most important section of statistical methodology is widely used – construction of statistical indexes. In the course of the analysis, a method of statistical classifications is applied. A significant role in the present research is given to the method of generalizing and analogue method, realizing that related terms should mean similar and almost similar contents. Modeling of competition and competitiveness is widely used in the present research, which made it possible to develop a logical model of competition following from the competition theory.Results. Based on the definitions’ survey the analysis of the subject matter of global

  9. Subjectivity and Objectivity: A Matter of Life and Death?

    Directory of Open Access Journals (Sweden)

    Gertrudis Van de Vijver

    2008-10-01

    Full Text Available In this paper, it is argued that the question ldquo;What is life?rdquo; time and again emergesmdash;and within the confines of an objectivistic/subjectivistic frame of thought has to emergemdash;as a symptom, a non-deciphered, cryptic message that insists on being interpreted. br /Our hypothesis is that the failure to measure up the living to the standards of objectification has been taken too frequently from an objectivistic angle, leading to a simple postponement of an objective treatment of the living, and meanwhile confining it to the domain of the subjective, the relative and the metaphorical. As a consequence, the truly important question of the co-constitutive relation between objectivity and subjectivity is thereby evaded. A critical, transcendental account can be relevant in this regard, not only because of the fact that objectivity and subjectivity are seen as co-constitutive, but also because it addresses the question of the embeddedness of objectivity and subjectivity from within the living dynamics.br /This hypothesis will be articulated on the basis of Erwin Schrouml;dingerrsquo;s famous little book on ldquo;What is life?rdquo;, in dialogue with Robert Rosenrsquo;s critical reading of it. It appears that Schrouml;dinger considered the living as a genuine challenge for classical objectification procedures. However, it is doubtful whether this brought him to a critical reading of objectivity or to the acknowledgment of a constitutive role of subjectivity in relation to objectivity. We argue that his viewpoint has the merit ofnbsp; expressing the difficulty of the living within the field of the physical sciences, but does not really transcend the objectivism/subjectivism opposition. At this point, Rosenrsquo;s relational account takes up the challenge more radically by acknowledging the need for a new epistemology and a new metaphysics in relation to living systems, and by attributing a place to classical objectivity from within this

  10. Dark Matter and Color Octets Beyond the Standard Model

    Energy Technology Data Exchange (ETDEWEB)

    Krnjaic, Gordan Zdenko [Johns Hopkins Univ., Baltimore, MD (United States)

    2012-07-01

    Although the Standard Model (SM) of particles and interactions has survived forty years of experimental tests, it does not provide a complete description of nature. From cosmological and astrophysical observations, it is now clear that the majority of matter in the universe is not baryonic and interacts very weakly (if at all) via non-gravitational forces. The SM does not provide a dark matter candidate, so new particles must be introduced. Furthermore, recent Tevatron results suggest that SM predictions for benchmark collider observables are in tension with experimental observations. In this thesis, we will propose extensions to the SM that address each of these issues.

  11. Scalar dark matter in scale invariant standard model

    Energy Technology Data Exchange (ETDEWEB)

    Ghorbani, Karim [Physics Department, Faculty of Sciences,Arak University, Arak 38156-8-8349 (Iran, Islamic Republic of); Ghorbani, Hossein [Institute for Research in Fundamental Sciences (IPM),School of Particles and Accelerators, P.O. Box 19395-5531, Tehran (Iran, Islamic Republic of)

    2016-04-05

    We investigate single and two-component scalar dark matter scenarios in classically scale invariant standard model which is free of the hierarchy problem in the Higgs sector. We show that despite the very restricted space of parameters imposed by the scale invariance symmetry, both single and two-component scalar dark matter models overcome the direct and indirect constraints provided by the Planck/WMAP observational data and the LUX/Xenon100 experiment. We comment also on the radiative mass corrections of the classically massless scalon that plays a crucial role in our study.

  12. Elementary particles, dark matter candidate and new extended standard model

    Science.gov (United States)

    Hwang, Jaekwang

    2017-01-01

    Elementary particle decays and reactions are discussed in terms of the three-dimensional quantized space model beyond the standard model. Three generations of the leptons and quarks correspond to the lepton charges. Three heavy leptons and three heavy quarks are introduced. And the bastons (new particles) are proposed as the possible candidate of the dark matters. Dark matter force, weak force and strong force are explained consistently. Possible rest masses of the new particles are, tentatively, proposed for the experimental searches. For more details, see the conference paper at https://www.researchgate.net/publication/308723916.

  13. "Frustrated" or "Surprised?" An Examination of the Perspectives of Spanish Teacher Candidates regarding the Praxis II Subject-Matter Tests

    Science.gov (United States)

    Moser, Kelly

    2012-01-01

    Researchers (Sandarg & Schomber, 2009; Wilkerson, Schomber, & Sandarg, 2004) have urged the profession to develop a new subject-matter licensure test to reflect the best practices in the foreign language classroom. In October 2010, the Praxis II: World Language Test joined the Praxis Series. Given that this standards-driven test differs…

  14. Cerebral white matter lesions and subjective cognitive dysfunction - The Rotterdam Scan Study

    NARCIS (Netherlands)

    de Groot, J.C.; de Leeuw, FE; Oudkerk, M; Hofman, A; Jolles, J; Breteler, MMB

    2001-01-01

    Objective: To determine the relationship between cerebral white matter lesions (WML) and subjective cognitive dysfunction. Background: Subjective cognitive dysfunction is present when a person perceives failures of cognitive function. When annoying enough, these failures will be expressed as

  15. 48 CFR 52.227-10 - Filing of Patent Applications-Classified Subject Matter.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Filing of Patent... Text of Provisions and Clauses 52.227-10 Filing of Patent Applications—Classified Subject Matter. As prescribed at 27.203-2, insert the following clause: Filing of Patent Applications—Classified Subject Matter...

  16. Beyond "Either-Or" Thinking: John Dewey and Confucius on Subject Matter and the Learner

    Science.gov (United States)

    Tan, Charlene

    2016-01-01

    This article compares the educational thought of John Dewey and Confucius on the nature of and relationship between subject matter and the learner. There is a common perception in the existing literature and discourse that Dewey advocates child- or learner-centred education whereas Confucius privileges subject matter via textual transmission.…

  17. Florida Master Teacher Program: Testing Teacher Subject Matter Knowledge.

    Science.gov (United States)

    Lavely, Carolyn; And Others

    1986-01-01

    The efforts of the Florida Institute for Instructional Research and Practice in designing, developing, and analyzing the subject area knowledge tests of the Florida Master Teacher Program are described. A total of 13 subject area examinations was developed in 1984-85, and 5 additional tests were developed the following year. For each subject area…

  18. GP teachers' subject matter knowledge in the context of a tutorial: the preparation and delivery compared.

    Science.gov (United States)

    Cantillon, Peter; de Grave, Willem

    2012-05-01

    Clinical teachers use several different types of knowledge in the act of teaching. These include content knowledge (subject matter), knowledge of how to teach (pedagogy) and knowledge of learners (context). Most attention in faculty development has been on how to teach rather than what is taught. The quality of a teacher's subject matter knowledge is likely to be a critical determinant of how well a subject is presented, communicated and learned. We therefore set out to examine teachers' subject matter knowledge in the context of a general practice tutorial on grade 1 hypertension. This study is part of a larger study that employed a mixed method approach (concept mapping, phenomenological interviews and video-stimulated recall) to examine differences between clinical educators in subject matter knowledge, pedagogical knowledge and knowledge of the learning environment in the context of general practice education. This paper presents the concept map data findings from the larger study as well as the parts of the phenomenological interviews that relate to subject matter knowledge and beliefs. We found that there were marked differences in the quality and elaborative structure of GP teachers' knowledge in the concept maps completed prior to the tutorials. These differences were also predictive of differences in the content presented to learners in tutorials. Teachers' beliefs about subject matter were also likely to have affected what they chose to teach about and how they presented it. Subject matter knowledge varies considerably between GP teachers in the context of a common and relatively simple tutorial. Differences in the quality of subject matter knowledge matter because they have a profound effect on what is learned and how it is learned. Faculty development for clinical educators needs to pay heed to the quality of subject matter knowledge in addition to its more common pedagogical focus.

  19. 78 FR 3085 - National Ambient Air Quality Standards for Particulate Matter

    Science.gov (United States)

    2013-01-15

    ... Air Quality Standards for Particulate Matter; Final Rule #0;#0;Federal Register / Vol. 78 , No. 10..., 51, 52, 53 and 58 RIN 2060-AO47 National Ambient Air Quality Standards for Particulate Matter AGENCY... criteria and the national ambient air quality standards (NAAQS) for particulate matter (PM), the EPA is...

  20. New extended standard model, dark matters and relativity theory

    Science.gov (United States)

    Hwang, Jae-Kwang

    2016-03-01

    Three-dimensional quantized space model is newly introduced as the extended standard model. Four three-dimensional quantized spaces with total 12 dimensions are used to explain the universes including ours. Electric (EC), lepton (LC) and color (CC) charges are defined to be the charges of the x1x2x3, x4x5x6 and x7x8x9 warped spaces, respectively. Then, the lepton is the xi(EC) - xj(LC) correlated state which makes 3x3 = 9 leptons and the quark is the xi(EC) - xj(LC) - xk(CC) correlated state which makes 3x3x3 = 27 quarks. The new three bastons with the xi(EC) state are proposed as the dark matters seen in the x1x2x3 space, too. The matter universe question, three generations of the leptons and quarks, dark matter and dark energy, hadronization, the big bang, quantum entanglement, quantum mechanics and general relativity are briefly discussed in terms of this new model. The details can be found in the article titled as ``journey into the universe; three-dimensional quantized spaces, elementary particles and quantum mechanics at https://www.researchgate.net/profile/J_Hwang2''.

  1. Generating a non-English subjectivity lexicon: relations that matter

    NARCIS (Netherlands)

    Jijkoun, V.; Hofmann, K.

    2009-01-01

    We describe a method for creating a non-English subjectivity lexicon based on an English lexicon, an online translation service and a general purpose thesaurus: Wordnet. We use a PageRank-like algorithm to bootstrap from the translation of the English lexicon and rank the words in the thesaurus by

  2. Preservice History Teachers' Perceptions of Subject Matter Competency

    Science.gov (United States)

    Yildirim, Tercan; Yazici, Fatih

    2017-01-01

    Teachers should be able to understand conceptual constructs, viewpoints, and principles related to their field and organize teaching process accordingly. This is valid also for history teachers. They are expected to comprehend the basic conceptions related to subject areas and reflect them on classroom practices. The association between subject…

  3. Didactic Matters in Teaching Subjects of Economics at the College

    Directory of Open Access Journals (Sweden)

    Rita Strazdienė

    2011-04-01

    Full Text Available It has been stated in Lithuania‘s National School Concept that the primary goal of the education of Lithuania is to secure the best possible comprehensive development of physical, psychological and spiritual human powers, to create conditions for the unfolding of the personal individuality. The subject of my teaching is economic theory. We face economic questions every day and in all areas of life. Therefore, my purpose is to acquaint college students, who do not study economics, with economic basics, to develop economic thinking and literacy. Greatest attention is paid to describe economic concepts and to use them in practice. Economics can not be learned through observing, one must work, analyse, solve practical exercises, search for correct answers. The purpose of the article is to assess the students‘ approach to the relevance of the subjects of economics. It is sought to identify the possibilities of applying new methods for teaching economic subjects and of selecting a teaching method in accordance with the students‘ level of preparation. The assessment of the research carried out enables to conclude that teaching economics forms students‘ capacities of a wide range, stimulates their self-expression, prepares young people to work in market conditions. The following methods of the research have been employed: pedagogic observation, questionnaire (survey, analysis of scientific literature and generalization.

  4. The subject genitive in the standard Serbian language

    Directory of Open Access Journals (Sweden)

    Antonić Ivana

    2005-01-01

    Full Text Available The paper presents a review of syntactic-semantic structures with the so-called subject genitive, it describes and in a specific way compares all syntactic-semantic models with this type of genitive and discusses the necessary syntactic-semantic conditions which influence its appearance with the comment on the necessary pragmatic conditions where it is relevant. In comparison with the interpretations existing so far, this category is somewhat extended, and the appearance of genitive in specific models mentioned by other authors, too - is explicitly classified into this category, which has not been the case before. Subject genitive, as an exponent of the grammatical subject in the deep predication (full verbal lexeme [condensed by the deverbal noun] or copulative with the adjective as a semantic core [condensed by the deadjectival noun], or the predication of the reduced relative clause in the function of the restrictive identifier of the basic noun of the type nomina loci and nomina collectiva or as a denotator of the semantic subject, in both cases with the meaning of agent - the direct performer of the activity or an intermediary, but also a pseudo-agent, e.g. the indicator of a characteristic, of existence, objects instrument, of the entity created in the process of the verb activity possessor, causer, indicator of a state or feeling, disponent (temporary possessor - is realized equally in nominal and verbal structures, and in a particular instance also in the occasional variant of the sentence with one type of modal particles (evo, eto, eno, gle in a specific pragmatic situation. In the Standard Serbian Language the subject genitive is the element of the secondary syntactic-semantic structures - generated from the basic deep, prototypical, structures (all models except the model with the personal and the model with the medial predication, or the element of the basic syntactic-semantic structures but so-called converse structures (the model

  5. 37 CFR 1.110 - Inventorship and date of invention of the subject matter of individual claims.

    Science.gov (United States)

    2010-07-01

    ... invention of the subject matter of individual claims. 1.110 Section 1.110 Patents, Trademarks, and... invention of the subject matter of individual claims. When more than one inventor is named in an application... claim in the application or patent. Where appropriate, the invention dates of the subject matter of each...

  6. The COBE normalization for standard cold dark matter

    Science.gov (United States)

    Bunn, Emory F.; Scott, Douglas; White, Martin

    1995-01-01

    The Cosmic Background Explorer Satellite (COBE) detection of microwave anisotropies provides the best way of fixing the amplitude of cosmological fluctuations on the largest scales. This normalization is usually given for an n = 1 spectrum, including only the anisotropy caused by the Sachs-Wolfe effect. This is certainly not a good approximation for a model containing any reasonable amount of baryonic matter. In fact, even tilted Sachs-Wolfe spectra are not a good fit to models like cold dark matter (CDM). Here, we normalize standard CDM (sCDM) to the two-year COBE data and quote the best amplitude in terms of the conventionally used measures of power. We also give normalizations for some specific variants of this standard model, and we indicate how the normalization depends on the assumed values on n, Omega(sub B) and H(sub 0). For sCDM we find the mean value of Q = 19.9 +/- 1.5 micro-K, corresponding to sigma(sub 8) = 1.34 +/- 0.10, with the normalization at large scales being B = (8.16 +/- 1.04) x 10(exp 5)(Mpc/h)(exp 4), and other numbers given in the table. The measured rms temperature fluctuation smoothed on 10 deg is a little low relative to this normalization. This is mainly due to the low quadrupole in the data: when the quadrupole is removed, the measured value of sigma(10 deg) is quite consistent with the best-fitting the mean value of Q. The use of the mean value of Q should be preferred over sigma(10 deg), when its value can be determined for a particular theory, since it makes full use of the data.

  7. Experiential Learning of Electronics Subject Matter in Middle School Robotics Courses

    Science.gov (United States)

    Rihtaršic, David; Avsec, Stanislav; Kocijancic, Slavko

    2016-01-01

    The purpose of this paper is to investigate whether the experiential learning of electronics subject matter is effective in the middle school open learning of robotics. Electronics is often ignored in robotics courses. Since robotics courses are typically comprised of computer-related subjects, and mechanical and electrical engineering, these…

  8. One Health in food safety and security education: Subject matter outline for a curricular framework

    Directory of Open Access Journals (Sweden)

    John A. Angelos

    2017-06-01

    Full Text Available Educating students in the range of subjects encompassing food safety and security as approached from a One Health perspective requires consideration of a variety of different disciplines and the interrelationships among disciplines. The Western Institute for Food Safety and Security developed a subject matter outline to accompany a previously published One Health in food safety and security curricular framework. The subject matter covered in this outline encompasses a variety of topics and disciplines related to food safety and security including effects of food production on the environment. This subject matter outline should help guide curriculum development and education in One Health in food safety and security and provides useful information for educators, researchers, students, and public policy-makers facing the inherent challenges of maintaining and/or developing safe and secure food supplies without destroying Earth's natural resources.

  9. Trends in the journal of nematology, 1969-2009: authors, States, nematodes, and subject matter.

    Science.gov (United States)

    McSorley, R

    2011-06-01

    Issues of the Journal of Nematology from 1969-2009 were examined to determine trends in authorship and subject matter. Data were collected on authors, affiliations, locations, funding, nematodes, and nematological subject matter, and then compared among the 4 decades involved. Some of the more prominent changes noted included: a decrease (P Journal of Nematology in the 1990s and 2000s from a peak in the 1980s; an increase (P Journal of Nematology from 1969-2009. The greatest changes in subject matter were increases in papers on biological control and resistance in the 1990s and 2000s compared to the 1970s and 1980s. Additional trends and subjects are discussed, and data are provided comparing differences among the 4 decades for various aspects of nematology.

  10. One Health in food safety and security education: Subject matter outline for a curricular framework.

    Science.gov (United States)

    Angelos, John A; Arens, Amanda L; Johnson, Heather A; Cadriel, Jessica L; Osburn, Bennie I

    2017-06-01

    Educating students in the range of subjects encompassing food safety and security as approached from a One Health perspective requires consideration of a variety of different disciplines and the interrelationships among disciplines. The Western Institute for Food Safety and Security developed a subject matter outline to accompany a previously published One Health in food safety and security curricular framework. The subject matter covered in this outline encompasses a variety of topics and disciplines related to food safety and security including effects of food production on the environment. This subject matter outline should help guide curriculum development and education in One Health in food safety and security and provides useful information for educators, researchers, students, and public policy-makers facing the inherent challenges of maintaining and/or developing safe and secure food supplies without destroying Earth's natural resources.

  11. Fiberprint: A subject fingerprint based on sparse code pooling for white matter fiber analysis.

    Science.gov (United States)

    Kumar, Kuldeep; Desrosiers, Christian; Siddiqi, Kaleem; Colliot, Olivier; Toews, Matthew

    2017-09-01

    White matter characterization studies use the information provided by diffusion magnetic resonance imaging (dMRI) to draw cross-population inferences. However, the structure, function, and white matter geometry vary across individuals. Here, we propose a subject fingerprint, called Fiberprint, to quantify the individual uniqueness in white matter geometry using fiber trajectories. We learn a sparse coding representation for fiber trajectories by mapping them to a common space defined by a dictionary. A subject fingerprint is then generated by applying a pooling function for each bundle, thus providing a vector of bundle-wise features describing a particular subject's white matter geometry. These features encode unique properties of fiber trajectories, such as their density along prominent bundles. An analysis of data from 861 Human Connectome Project subjects reveals that a fingerprint based on approximately 3000 fiber trajectories can uniquely identify exemplars from the same individual. We also use fingerprints for twin/sibling identification, our observations consistent with the twin data studies of white matter integrity. Our results demonstrate that the proposed Fiberprint can effectively capture the variability in white matter fiber geometry across individuals, using a compact feature vector (dimension of 50), making this framework particularly attractive for handling large datasets. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. 77 FR 38760 - National Ambient Air Quality Standards for Particulate Matter; Correction

    Science.gov (United States)

    2012-06-29

    ... AGENCY 40 CFR Parts 50, 51, 52, 53, and 58 RIN 2060-AO47 National Ambient Air Quality Standards for... revise the national ambient air quality standards (NAAQS) for particulate matter (PM). This action...: Questions concerning the ``National Ambient Air Quality Standards for Particulate Matter'' proposed rule...

  13. Trends in the Journal of Nematology, 1969-2009: Authors, States, Nematodes, and Subject Matter

    OpenAIRE

    McSorley, R.

    2011-01-01

    Issues of the Journal of Nematology from 1969-2009 were examined to determine trends in authorship and subject matter. Data were collected on authors, affiliations, locations, funding, nematodes, and nematological subject matter, and then compared among the 4 decades involved. Some of the more prominent changes noted included: a decrease (P < 0.05) in the number of papers published in the Journal of Nematology in the 1990s and 2000s from a peak in the 1980s; an increase (P < 0.05) in number o...

  14. Non-standard interactions and neutrinos from dark matter annihilation in the Sun

    OpenAIRE

    Demidov, S. V.

    2017-01-01

    We perform an analysis of the influence of non-standard neutrino interactions (NSI) on neutrino signal from dark matter annihilations in the Sun. Taking experimentally allowed benchmark values for the matter NSI parameters we show that the evolution of such neutrinos with energies at GeV scale can be considerably modified. We simulate propagation of neutrinos from the Sun to the Earth for realistic dark matter annihilation channels and find that the matter NSI can results in at least 30% corr...

  15. 77 FR 39205 - Public Hearings for Proposed Rules-National Ambient Air Quality Standards for Particulate Matter

    Science.gov (United States)

    2012-07-02

    ... titled, ``National Ambient Air Quality Standards for Particulate Matter,'' that is scheduled to be... and secondary national ambient air quality standards (NAAQS) for particulate matter (PM) to provide... below under SUPPLEMENTARY INFORMATION. Questions concerning the ``National Ambient Air Quality Standards...

  16. Using Learning Analytics to Enhance Student Learning in Online Courses Based on Quality Matters Standards

    Science.gov (United States)

    Martin, Florence; Ndoye, Abdou; Wilkins, Patricia

    2016-01-01

    Quality Matters is recognized as a rigorous set of standards that guide the designer or instructor to design quality online courses. We explore how Quality Matters standards guide the identification and analysis of learning analytics data to monitor and improve online learning. Descriptive data were collected for frequency of use, time spent, and…

  17. The Effects of CLIL Education on the Subject Matter (Mathematics) and the Target Language (English)

    Science.gov (United States)

    Ouazizi, Khalid

    2016-01-01

    This paper investigates the effects of Content and Language Integrated Learning, CLIL for short, on both the attainment of the subject matter, mathematics in our case, hence the content aspect of CLIL. The second axes of research focuses on the effect of CLIL on the learners' proficiency vis-à-vis the language of instruction, epitomized here by…

  18. On the Importance of Subject Matter in Mathematics Education: A Conversation with Erich Christian Wittmann

    Science.gov (United States)

    Akinwunmi, Kathrin; Höveler, Karina; Schnell, Susanne

    2014-01-01

    Erich Christian Wittmann is one of the primary founders of mathematics education research as an autonomous field of work and research in Germany. The interview presented here reflects on his role in promoting mathematics education as a design science. The interview addresses the following topics: (1) The importance of subject matter in…

  19. The Structure of Subject Matter Content and Its Instructional Design Implications

    Science.gov (United States)

    Reigeluth, Charles M.; And Others

    1978-01-01

    Four types of fundamental structures are briefly described and illustrated: the learning hierarchy, the procedural hierarchy, the taxonomy, and the model. Then a theoretical framework is presented for classifying types of subject matter content, and some implications of these content classifications are discussed. (VT)

  20. Pre-Service Geography Teachers' Confidence in Geographical Subject Matter Knowledge and Teaching Geographical Skills

    Science.gov (United States)

    Harte, Wendy; Reitano, Paul

    2015-01-01

    This research tracked the confidence of 16 undergraduate and postgraduate pre-service geography teachers as they completed a single semester, senior phase geography curriculum course. The study focused specifically on the pre-service teachers' confidence in geographical subject matter knowledge and their confidence in teaching geographical skills.…

  1. The Designer-by-Assignment in Practice: Instructional Design Thinking of Subject Matter Experts

    Science.gov (United States)

    Pesce, Sandra V.

    2012-01-01

    Designers-by-assignment, or subject matter experts (SMEs) who are pressed into training service, have become common in the workplace. A review of more than 24 studies on expert and novice instructional designers, however, revealed that little is known about how designers-by-assignment think about design and make design decisions in the field. A…

  2. The Dialectical Nature of Writing and Its Implications for Learning Subject Matter Courses.

    Science.gov (United States)

    Males, Terry

    1997-01-01

    Looks at writing as a dialectical affair--"dialectic" refers both to the dialogical nature of writing and the opportunity it opens up for the writer in coming to a new understanding of the subject matter. Uses H. Gadamer's philosophical hermeneutics as a starting point for developing writing as a dialectical process. (PA)

  3. Reclaiming the Subject Matter as a Guide to Mutual Understanding: Effectiveness and Ethics in Interpersonal Interaction.

    Science.gov (United States)

    Deetz, Stanley

    1990-01-01

    Presents H. G. Gadamer's ontology of understanding as a developmental foundation for interpersonal system ethics. Conceptualizes interaction in terms of demand that the subject matter places on openly formed mutual understanding. Shows unethical interactions as practices which prohibit this development. Provides examples of processes by which…

  4. Insight on AV-45 binding in white and grey matter from histogram analysis: a study on early Alzheimer's disease patients and healthy subjects

    Energy Technology Data Exchange (ETDEWEB)

    Nemmi, Federico; Saint-Aubert, Laure; Peran, Patrice [Inserm, Imagerie Cerebrale et Handicaps Neurologiques UMR 825, Centre Hospitalier Universitaire de Toulouse (France); Universite de Toulouse, UPS, Imagerie Cerebrale et Handicaps Neurologiques UMR 825, Centre Hospitalier Universitaire de Toulouse, Toulouse (France); Adel, Djilali; Salabert, Anne-Sophie; Payoux, Pierre [Inserm, Imagerie Cerebrale et Handicaps Neurologiques UMR 825, Centre Hospitalier Universitaire de Toulouse (France); Universite de Toulouse, UPS, Imagerie Cerebrale et Handicaps Neurologiques UMR 825, Centre Hospitalier Universitaire de Toulouse, Toulouse (France); Centre Hospitalier Universitaire de Toulouse, Service de Medecine Nucleaire, Pole Imagerie, Toulouse (France); Pariente, Jeremie [Inserm, Imagerie Cerebrale et Handicaps Neurologiques UMR 825, Centre Hospitalier Universitaire de Toulouse (France); Universite de Toulouse, UPS, Imagerie Cerebrale et Handicaps Neurologiques UMR 825, Centre Hospitalier Universitaire de Toulouse, Toulouse (France); Centre Hospitalier Universitaire de Toulouse, Service de Neurologie, Pole Neurosciences, Toulouse (France); Barbeau, Emmanuel J. [Centre Hospitalier Universitaire de Toulouse, Service de Neurologie, Pole Neurosciences, Toulouse (France); Universite de Toulouse, UPS, Centre de Recherche Cerveau et Cognition, CNRS, CerCo, Toulouse (France)

    2014-07-15

    AV-45 amyloid biomarker is known to show uptake in white matter in patients with Alzheimer's disease (AD), but also in the healthy population. This binding, thought to be of a non-specific lipophilic nature, has not yet been investigated. The aim of this study was to determine the differential pattern of AV-45 binding in white matter in healthy and pathological populations. We recruited 24 patients presenting with AD at an early stage and 17 matched, healthy subjects. We used an optimized positron emission tomography-magnetic resonance imaging (PET-MRI) registration method and an approach based on an intensity histogram using several indices. We compared the results of the intensity histogram analyses with a more canonical approach based on target-to-cerebellum Standard Uptake Value (SUVr) in white and grey matter using MANOVA and discriminant analyses. A cluster analysis on white and grey matter histograms was also performed. White matter histogram analysis revealed significant differences between AD and healthy subjects, which were not revealed by SUVr analysis. However, white matter histograms were not decisive to discriminate groups, and indices based on grey matter only showed better discriminative power than SUVr. The cluster analysis divided our sample into two clusters, showing different uptakes in grey, but also in white matter. These results demonstrate that AV-45 binding in white matter conveys subtle information not detectable using the SUVr approach. Although it is not more efficient than standard SUVr in discriminating AD patients from healthy subjects, this information could reveal white matter modifications. (orig.)

  5. What Do Subject Matter Experts Have to Say about Participating in Education and Outreach?

    Science.gov (United States)

    Manning, Colleen; NASA's Universe of Learning Team

    2018-01-01

    NASA’s Universe of Learning partners wish to actively engage with Subject Matter Experts (scientists and engineers) throughout the design, development, and delivery of products, programs, and professional development. In order to ensure these engagement efforts aligned with the needs of Subject Matter Experts, the external evaluators conducted an online survey. The subject pool included the scientists and engineers employed at the partner organizations as well as other scientists and engineers affiliated with NASA’s Astrophysics missions and research programs. This presentation will describe scientists’/engineers’ interest in various types of education/outreach, their availability to participate in education/outreach, factors that would encourage their participation in education/outreach, and the preparation and support they have for participation in education/outreach.

  6. John Dewey on theory of learning and inquiry: The scientific method and subject matter

    Science.gov (United States)

    Chen, Po-Nien

    This study examines the educational debate between Dewey and some of his critics on the merits of learning the scientific method. Four of Dewey's critics---Hutchins, Hirsch, Hirst, and Scheffler criticize Dewey for over-emphasizing the importance of the scientific method and under-emphasizing the importance of subject matter in education. This dissertation argues that these critics misunderstand Dewey's use of the scientific method and its importance in education. It argues that Dewey conceives of the scientific method in two different ways: first as an attitude and second as a tool. It also argues that, by failing to understand this critical distinction, these critics misunderstand the role of the scientific method in education. The dissertation concludes by showing that, educationally, Dewey's ideas of the scientific method have different meanings in different context. It analyzes the scientific method as empirical method, critical thinking, cooperative learning, and creative thinking, and shows the place of subject matter in each of them.

  7. White Matter Hyperintensity Associations with Cerebral Blood Flow in Elderly Subjects Stratified by Cerebrovascular Risk.

    Science.gov (United States)

    Bahrani, Ahmed A; Powell, David K; Yu, Guoquiang; Johnson, Eleanor S; Jicha, Gregory A; Smith, Charles D

    2017-04-01

    This study aims to add clarity to the relationship between deep and periventricular brain white matter hyperintensities (WMHs), cerebral blood flow (CBF), and cerebrovascular risk in older persons. Deep white matter hyperintensity (dWMH) and periventricular white matter hyperintensity (pWMH) and regional gray matter (GM) and white matter (WM) blood flow from arterial spin labeling were quantified from magnetic resonance imaging scans of 26 cognitively normal elderly subjects stratified by cerebrovascular disease (CVD) risk. Fluid-attenuated inversion recovery images were acquired using a high-resolution 3-dimensional (3-D) sequence that reduced partial volume effects seen with slice-based techniques. dWMHs but not pWMHs were increased in patients at high risk of CVD; pWMHs but not dWMHs were associated with decreased regional cortical (GM) blood flow. We also found that blood flow in WM is decreased in regions of both pWMH and dWMH, with a greater degree of decrease in pWMH areas. WMHs are usefully divided into dWMH and pWMH regions because they demonstrate differential effects. 3-D regional WMH volume is a potentially valuable marker for CVD based on associations with cortical CBF and WM CBF. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  8. Problems Faced By Elementary School Second Grade English Subject Matter Teachers

    Directory of Open Access Journals (Sweden)

    Belgin Bal Incebacak

    2017-11-01

    Full Text Available The objective of thisstudy isto determine the problems experienced by subject matter teachers while instructing English lessons in the second grade of elementary school. What are the problemsfaced by English subject matter teachers when they instruct in 2nd grade lessons? In this research the descriptive modeling, which is one of the qualitative research methods, was employed. In accordance with this objective, we worked with 8 subject matter teachers from 5 different schoolsinAtakum and Ilkadim districtslocated in downtown Samsun, through easily accessible case sampling. The semi-structured “English Course Interview Form’’was applied to the teachers. In the study, descriptive survey model was employed, since it was aimed to reveal the current status of qualitative research methods.According to the results obtained from the research, the content was configured and presented under 5 themes. They were categorized as: 1. the problems experienced in classroom management, 2. the problems in physical and cognitive readiness, 3. the problems experienced in the learning and teacher process, 4. the problems seen in counseling, 5. the problems experienced in assessment and evaluation. In conclusion, the teachers stated that they had problems with managing the classroom, especially with the second grade students, whom are younger than others. It is observed that the change for teaching English at a younger age has been appropriate. Our teachersstated that they required in-service training so as to adapt to this aforementioned change.

  9. A combined study of source, detector and matter non-standard neutrino interactions at DUNE

    Energy Technology Data Exchange (ETDEWEB)

    Blennow, Mattias [Department of Theoretical Physics, School of Engineering Sciences,KTH Royal Institute of Technology, AlbaNova University Center,106 91 Stockholm (Sweden); Choubey, Sandhya [Department of Theoretical Physics, School of Engineering Sciences,KTH Royal Institute of Technology, AlbaNova University Center,106 91 Stockholm (Sweden); Harish-Chandra Research Institute,Chhatnag Road, Jhunsi, Allahabad 211 019 (India); Ohlsson, Tommy [Department of Theoretical Physics, School of Engineering Sciences,KTH Royal Institute of Technology, AlbaNova University Center,106 91 Stockholm (Sweden); Pramanik, Dipyaman [Harish-Chandra Research Institute,Chhatnag Road, Jhunsi, Allahabad 211 019 (India); Raut, Sushant K. [Department of Theoretical Physics, School of Engineering Sciences,KTH Royal Institute of Technology, AlbaNova University Center,106 91 Stockholm (Sweden)

    2016-08-12

    We simultaneously investigate source, detector and matter non-standard neutrino interactions at the proposed DUNE experiment. Our analysis is performed using a Markov Chain Monte Carlo exploring the full parameter space. We find that the sensitivity of DUNE to the standard oscillation parameters is worsened due to the presence of non-standard neutrino interactions. In particular, there are degenerate solutions in the leptonic mixing angle θ{sub 23} and the Dirac CP-violating phase δ. We also compute the expected sensitivities at DUNE to the non-standard interaction parameters. We find that the sensitivities to the matter non-standard interaction parameters are substantially stronger than the current bounds (up to a factor of about 15). Furthermore, we discuss correlations between the source/detector and matter non-standard interaction parameters and find a degenerate solution in θ{sub 23}. Finally, we explore the effect of statistics on our results.

  10. 40 CFR 80.200 - What gasoline is subject to the sulfur standards and requirements?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false What gasoline is subject to the sulfur... (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Gasoline Sulfur Standards § 80.200 What gasoline is subject to the sulfur standards and requirements? For the purpose of...

  11. 47 CFR 76.905 - Standards for identification of cable systems subject to effective competition.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Standards for identification of cable systems... Regulation § 76.905 Standards for identification of cable systems subject to effective competition. (a) Only the rates of cable systems that are not subject to effective competition may be regulated. (b) A cable...

  12. Reconstructing cosmological matter perturbations using standard candles and rulers

    Energy Technology Data Exchange (ETDEWEB)

    Alam, Ujjaini [Los Alamos National Laboratory; Sahni, Varun [IUCAA, PUNE; Starobinsky, Alexei A [LANDAU INST, MOSCOW

    2008-01-01

    For a large class of dark energy (DE) models, for which the effective gravitational constant is a constant and there is no direct exchange of energy between DE and dark matter (DM), knowledge of the expansion history suffices to reconstruct the growth factor of linearized density perturbations in the non-relativistic matter component on scales much smaller than the Hubble distance. In this paper, we develop a non-parametric method for extracting information about the perturbative growth factor from data pertaining to the luminosity or angular size distances. A comparison of the reconstructed density contrast with observations of large-scale structure and gravitational lensing can help distinguish DE models such as the cosmological constant and quintessence from models based on modified gravity theories as well as models in which DE and DM are either unified or interact directly. We show that for current supernovae (SNe) data, the linear growth factor at z = 0.3 can be constrained to 5% and the linear growth rate to 6%. With future SNe data, such as expected from the Joint Dark Energy Mission, we may be able to constrain the growth factor to 2%-3% and the growth rate to 3%-4% at z = 0.3 with this unbiased, model-independent reconstruction method. For future baryon acoustic oscillation data which would deliver measurements of both the angular diameter distance and the Hubble parameter, it should be possible to constrain the growth factor at z = 2.5%-9%. These constraints grow tighter with the errors on the data sets. With a large quantity of data expected in the next few years, this method can emerge as a competitive tool for distinguishing between different models of dark energy.

  13. Methods to model particulate matter clarification of unit operations subject to unsteady loadings.

    Science.gov (United States)

    Spelman, David; Sansalone, John J

    2017-05-15

    Stormwater, and also wastewater unit operations (UOs) to a much lower extent, are subject to unsteady hydrodynamic and particulate matter (PM) fluxes. Simulating fully transient clarification of hetero-disperse PM requires much greater computational expense compared to steady simulations. An alternative to fully unsteady methods are stepwise steady (SS) methods which use stepwise steady flow transport and fate to approximate unsteady PM clarification of a UO during transient hydraulic loadings such as rainfall-runoff. The rationale is reduced computational effort for computational fluid dynamics (CFD) compared to simulating continuous unsteadiness of such events. An implicit solution stepwise steady (IS3) method is one approach which builds upon previous SS methods. The IS3 method computes steady flows that are representative of unsteady PM transport throughout an unsteady loading. This method departs from some previous SS methods that assume PM fate can be simulated with an instantaneous clarifier (basin) influent flowrate coupled with a PM input. In this study, various SS methods were tested for basins of varying size and residence time to examine PM fate. Differences between SS methods were a function of turnover fraction indicating the role of unsteady flowrates on PM transport for larger basins of longer residence times. The breakpoint turnover fraction was between two and three. The IS3 method best approximated unsteady behavior of larger basins. These methods identified limitations when utilizing standard event-based loading analysis for larger basins. For basins with a turnover fraction less than two, the majority of effluent PM did not originate from the event-based flow; originating from previous event loadings or existing storage. Inter- and multiple event processes and interactions, that are dependent on this inflow turnover fraction, are not accounted for by single event-based inflow models. Results suggest the use of long-term continuous modeling

  14. Extracting the properties of dark matter particles in minimal extensions of the standard model

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Maira Dutra Vasconcelos dos; Santos, Antonio Carlos Oliveira; Silva, Paulo Sergio Rodrigues da; Pires, Carlos Antonio de Sousa; Siqueira, Clarissa [Universidade Federal da Paraiba (UFPB), Joao Pessoa, PB (Brazil); Queiroz, Farinaldo da Silva [University of California (United States)

    2013-07-01

    Full text: Nature has provided a striking evidence for physics beyond the Standard Model, namely dark matter. Observations coming from a variety of sources point to the existence of a non-baryonic matter that accounts for roughly 27% of the total abundance of the universe and is composed of neutral, massive, stable and weakly interacting particles. Once the Standard Model has no candidate that fulfills all these properties we must extend it. There are many interesting proposals in the literature that have a good dark matter candidate. Essentially, all of them invoke an extended scalar or gauge sector. Here we aim to extract information about the underlying beyond Standard Model theory able to address the dark matter and many other theoretical puzzles through minimal extensions of the standard model. The minimality perspective it is a worthwhile approach because we can focus on the dark side of many particle physics models. We will carry on our investigation in a pedagogic way Firstly, we will add a neutral fermion, which is our dark matter candidate, and one neutral scalar, both being singlet under the Standard Model gauge group. In this model we compute the abundance of our dark matter candidate and the scattering cross sections off nuclei in order to face our results with the current direct detection experiments data. Secondly, we add a charged scalar field, which is predicted in many standard model extensions, to the first model and investigate the role of this scalar in our results. Lastly, we add a Z' boson to the latter model, and study how our results are affected, with the purpose of, further on, exploring the complementarity between direct detection and collider physics regarding the search of this boson. Thus, we will be able to extract precise information about the beyond Standard Model theory and the properties of the dark matter particles. (author)

  15. 75 FR 65594 - Approval and Promulgation of Air Quality Implementation Plans; Ohio; Particulate Matter Standards

    Science.gov (United States)

    2010-10-26

    ... have been necessary to attain and maintain the 2006 National Ambient Air Quality Standards for PM in... AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; Ohio; Particulate Matter Standards AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is...

  16. Notes on the Particulate Matter Standards in the European Union and the Netherlands

    Directory of Open Access Journals (Sweden)

    Hugo Priemus

    2009-03-01

    Full Text Available The distribution of Particulate Matter in the atmosphere, resulting from emissions produced by cars, trucks, ships, industrial estates and agricultural complexes, is a topical public health problem that has increased in recent decades due to environmental factors in advanced economies in particular. This contribution relates the health impact caused by concentrations of Particulate Matter (PM in ambient air to the PM standards, the size of the particles and spatial planning. Diverging impacts of PM standards in legal regulation are discussed. The authors present a review of the development of legal PM standards in the European Union, with a specific reference to The Netherlands.

  17. OntoBrowser: a collaborative tool for curation of ontologies by subject matter experts.

    Science.gov (United States)

    Ravagli, Carlo; Pognan, Francois; Marc, Philippe

    2017-01-01

    The lack of controlled terminology and ontology usage leads to incomplete search results and poor interoperability between databases. One of the major underlying challenges of data integration is curating data to adhere to controlled terminologies and/or ontologies. Finding subject matter experts with the time and skills required to perform data curation is often problematic. In addition, existing tools are not designed for continuous data integration and collaborative curation. This results in time-consuming curation workflows that often become unsustainable. The primary objective of OntoBrowser is to provide an easy-to-use online collaborative solution for subject matter experts to map reported terms to preferred ontology (or code list) terms and facilitate ontology evolution. Additional features include web service access to data, visualization of ontologies in hierarchical/graph format and a peer review/approval workflow with alerting. The source code is freely available under the Apache v2.0 license. Source code and installation instructions are available at http://opensource.nibr.com This software is designed to run on a Java EE application server and store data in a relational database. philippe.marc@novartis.com. © The Author 2016. Published by Oxford University Press.

  18. Habitual sleep durations and subjective sleep quality predict white matter differences in the human brain

    Directory of Open Access Journals (Sweden)

    Sakh Khalsa

    2017-06-01

    Full Text Available Self-imposed short sleep durations are increasingly commonplace in society, and have considerable health and performance implications for individuals. Reduced sleep duration over multiple nights has similar behavioural effects to those observed following acute total sleep deprivation, suggesting that lack of sleep affects brain function cumulatively. A link between habitual sleep patterns and functional connectivity has previously been observed, and the effect of sleep duration on the brain's intrinsic functional architecture may provide a link between sleep status and cognition. However, it is currently not known whether differences in habitual sleep patterns across individuals are related to changes in the brain's white matter, which underlies structural connectivity. In the present study we use diffusion–weighted imaging and a group comparison application of tract based spatial statistics (TBSS to investigate changes to fractional anisotropy (FA and mean diffusivity (MD in relation to sleep duration and quality, hypothesising that white matter metrics would be positively associated with sleep duration and quality. Diffusion weighted imaging data was acquired from a final cohort of 33 (23–29 years, 10 female, mean 25.4 years participants. Sleep patterns were assessed for a 14 day period using wrist actigraphs and sleep diaries, and subjective sleep quality with the Pittsburgh Sleep Quality Index (PSQI. Median splits based on total sleep time and PSQI were used to create groups of shorter/longer and poorer/better sleepers, whose imaging data was compared using TBSS followed by post-hoc correlation analysis in regions identified as significantly different between the groups. There were significant positive correlations between sleep duration and FA in the left orbito-frontal region and the right superior corona radiata, and significant negative correlations between sleep duration and MD in right orbito-frontal white matter and the right

  19. Asymmetric dark matter from spontaneous cogenesis in the supersymmetric standard model

    Energy Technology Data Exchange (ETDEWEB)

    Kamada, Kohei [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Yamaguchi, Masahide [Tokyo Institute of Technology (Japan). Dept. of Physics

    2012-01-15

    The observational relation between the density of baryon and dark matter in the Universe, {omega}{sub DM}/{omega}{sub B}{approx_equal}5, is one of the most difficult problems to solve in modern cosmology. We discuss a scenario that explains this relation by combining the asymmetric dark matter scenario and the spontaneous baryogenesis associated with the flat direction in the supersymmetric standard model. A part of baryon asymmetry is transferred to charge asymmetry D that dark matter carries, if a symmetry violating interaction that works at high temperature breaks not only B-L but also D symmetries simultaneously. In this case, the present number density of baryon and dark matter can be same order if the symmetric part of dark matter annihilates sufficiently. Moreover, the baryon number density can be enhanced as compared to that of dark matter if another B-L violating interaction is still in thermal equilibrium after the spontaneous genesis of dark matter, which accommodates a TeV scale asymmetric dark matter model. (orig.)

  20. Bias Corrections for Standardized Effect Size Estimates Used with Single-Subject Experimental Designs

    Science.gov (United States)

    Ugille, Maaike; Moeyaert, Mariola; Beretvas, S. Natasha; Ferron, John M.; Van den Noortgate, Wim

    2014-01-01

    A multilevel meta-analysis can combine the results of several single-subject experimental design studies. However, the estimated effects are biased if the effect sizes are standardized and the number of measurement occasions is small. In this study, the authors investigated 4 approaches to correct for this bias. First, the standardized effect…

  1. The Effects of Verbal Rewards and Punishment on Subject-Matter Growth of Culturally Disadvantaged First Grade Children.

    Science.gov (United States)

    Honeycutt, Joan K.; Soar, Robert S.

    The purpose of this study was to extend a relationship between teacher verbal rewarding and punishing behavior and subject matter growth previously obtained with middle-class postprimary children, with a different population; namely, first-grade, lower-class children. The subjects were 366 children and 20 teachers from first-grade classes…

  2. Knot numbers used as labels for identifying subject matter of a khipu

    Directory of Open Access Journals (Sweden)

    Alberto Saez-Rodriguez

    2013-03-01

    Full Text Available This investigation presents a new way to look at the numerical khipu, a knotted-string recording device from Pachacamac (Peru, and the types of information it contains. In addition to celestial coordinates, khipu knots apparently pertain to an early form of double-entry accounting. This study hypothesizes that the khipu sample has the recording capacity needed to register double-entry-like accounts. After the identification of its subject matter, the khipu sample was studied in an attempt to ascertain whether the knot values could represent instructions from the Inca state administration to a local accounting center. The results indicate that the numerical information in the pairing quadrants (determined by the distribution of S- and Z-knots should be read from top to bottom along the full length of the string and can then provide certain complementary details regarding the projected corn stocks of the Inca stat

  3. Subject matter knowledge, classroom management, and instructional practices in middle school science classrooms

    Science.gov (United States)

    Lee, Okhee

    This study examined the interrelationships among three major components of classroom teaching: subject matter content knowledge, classroom management, and instructional practices. The study involved two middle school science classes of different achievement levels taught by the same female teacher. The teacher held an undergraduate degree with a major in social studies and a minor in mathematics and science from an elementary teacher education program. The findings indicated that the teacher's limited knowledge of science content and her strict classroom order resulted in heavy dependence on the textbook and students' individual activities (e.g., seatwork) and avoidance of whole-class activities (e.g., discussion) similarly in both classes. Implications for educational practices and further research are discussed.

  4. 78 FR 19128 - Approval and Promulgation of Air Quality Implementation Plans; Ohio; Particulate Matter Standards

    Science.gov (United States)

    2013-03-29

    ... AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; Ohio; Particulate Matter Standards AGENCY: Environmental Protection Agency (EPA). ACTION: Direct final rule. SUMMARY: EPA...-2450. 4. Mail: Pamela Blakely, Chief, Control Strategies Section, Air Programs Branch (AR-18J), U.S...

  5. 78 FR 19164 - Approval and Promulgation of Air Quality Implementation Plans; Ohio; Particulate Matter Standards

    Science.gov (United States)

    2013-03-29

    ... AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; Ohio; Particulate Matter Standards AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is... Section, Air Programs Branch (AR-18J), U.S. Environmental Protection Agency, 77 West Jackson Boulevard...

  6. Adiabatic density perturbations and matter generation from the minimal supersymmetric standard model.

    Science.gov (United States)

    Enqvist, Kari; Kasuya, Shinta; Mazumdar, Anupam

    2003-03-07

    We propose that the inflaton is coupled to ordinary matter only gravitationally and that it decays into a completely hidden sector. In this scenario both baryonic and dark matter originate from the decay of a flat direction of the minimal supersymmetric standard model, which is shown to generate the desired adiabatic perturbation spectrum via the curvaton mechanism. The requirement that the energy density along the flat direction dominates over the inflaton decay products fixes the flat direction almost uniquely. The present residual energy density in the hidden sector is typically shown to be small.

  7. Secluded and putative flipped dark matter and Stueckelberg extensions of the standard model

    Science.gov (United States)

    Fortes, E. C. F. S.; Pleitez, V.; Stecker, F. W.

    2018-02-01

    We consider here three dark matter models with the gauge symmetry of the standard model plus an additional local U(1)D factor. One model is truly secluded and the other two models begin flipped, but end up secluded. All of these models include one dark fermion and one vector boson that gains mass via the Stueckelberg mechanism. We show that the would be flipped models provide an example dark matter composed of "almost least interacting particles" (ALIPs). Such particles are therefore compatible with the constraints obtained from both laboratory measurements and astrophysical observations.

  8. Grey-Matter Metabolism in Relation with White-Matter Lesions in Older Hypertensive Patients with Subjective Memory Complaints: A Pilot Voxel-Based Analysis Study.

    Science.gov (United States)

    Verger, Antoine; Hossu, Gabriela; Kearney-Schwartz, Anna; Bracard, Serge; Roch, Veronique; Van der Gucht, Axel; Fay, Renaud; Benetos, Athanase; Marie, Pierre-Yves; Joly, Laure

    2016-01-01

    This study aimed at assessing the changes in brain metabolism related to white-matter magnetic resonance (MR) hyperintensities of presumed vascular origin, with a voxel-based quantitative analysis of (18F)-fluorodesoxyglucose positron emission tomography (FDG-PET) imaging. Sixty older hypertensive patients with subjective memory complaints (75 ± 5 years, 34 women) were prospectively referred to FDG-PET and MRI brain imaging. The Statistical Parametric Mapping software was used to assess the correlation between brain distribution of FDG and white-matter hyperintensities assessed by the Fazekas score on MRI images. The Fazekas score was inversely related to FDG uptake, independently of age and gender, within 14 Brodmann areas located mainly in the frontal lobe but also in certain limbic, insular and temporal areas. This relationship was also found to be largely independent of the volume of grey matter expressed in percentage of cranial volume, an index of atrophy. White-matter MR hyperintensities of presumed vascular origin are cross-sectionally associated with a lower grey-matter metabolism, mainly but not only within frontal areas and independently of age, gender and grey-matter atrophy. © 2016 S. Karger AG, Basel.

  9. 'The body does matter': Women as embodied social subjects in Angela Carter's Nights at the Circus

    Directory of Open Access Journals (Sweden)

    Milosavljević Tatjana B.

    2017-01-01

    Full Text Available Postmodernism posed a crucial ontological challenge to reality, questioning what constitutes the real world, simultaneously interrogating the horizon of representation of this unstable reality in fiction. Feminism on the other hand equipped us with critical tools for interpreting the reality of being in the world in a gendered body, as well as with a conceptual apparatus for interpreting the manifold institutional and private oppressions of women's bodies that play out in women's daily lives and in the discourses that shape them, literary discourse being one of them. This paper argues that Angela Carter's 1984 novel Nights at the Circus, which is widely held as a postfeminist text due to its narrative commitment to transcending gender binaries, essentially uses the strategies of postmodern storytelling and characterization in order to explore women's embodied potentialities of agency i.e. their construction of subjectivity through body. We will argue that the hybrid magic realist narrative constructs Fevvers' body as a titillating postmodern performance, ontologically illusive and elusive, yet it grounds that same body in various socially effected predicaments and experiences that serve to show that even in the midst of a play of signifiers, in Patricia Waugh's words, 'the body does matter, at least to what has been the dominant perspective within British female fiction' (Waugh, 2006, p. 196. In other words, it may be argued that Carter's novel is invested in traditional second-wave feminist politics to the extent that it shows that a woman's body is an indispensable medium of being in the world with material consequences that bear on the formation of her subjectivity and possibility of agency, and through which she acts out her relationships to others and is acted upon.

  10. NASA's Universe of Learning: The Integral Role of Research Astronomers and Other Subject Matter Experts

    Science.gov (United States)

    Lee, Janice; Universe of Learning Team

    2018-01-01

    Astronomy seeks to understand the workings of the Universe on its largest scales, and to answer fundamental questions about the story of our origins. The science of astronomy thus naturally lends itself to informal education and public outreach activities, as it broadly captures the human imagination. There are at least three overall goals for investment of resources in Astronomy E/PO: to interest students in pursuing STEM education and careers; to develop Astronomy as context for teaching more basic physical and computer science in service of US National Education Goals; to help motivate continued public support of federally funded Astronomy research and technology development. Providing a full spectrum of opportunities for the public to learn about recent Astronomy discoveries is key to achieving these societal goals. Thus, the E/PO professional community must have an understanding of recent scientific/technological results, and engage with the researchers who are creating new knowledge to explicate that knowledge to the public. It stands to reason that researchers (or “subject matter experts, SMEs”) must be involved in and remain connected to the E/PO endeavor. In this talk, I will describe how research astronomers and other SMEs play an integral role in a full range of informal education programming developed by the NASA Universe of Learning collaboration, and opportunities to get involved.

  11. Cognitive Control and White Matter Callosal Microstructure in Methamphetamine Dependent Subjects: A DTI Study

    Science.gov (United States)

    Salo, Ruth; Nordahl, Thomas E; Buonocore, Michael H; Natsuaki, Yutaka; Waters, Christy; Moore, Charles D; Galloway, Gantt P; Leamon, Martin H

    2009-01-01

    Background Methamphetamine (MA) abuse causes damage to structures within the human cerebrum, with particular susceptibility to white matter (WM). Abnormalities have been reported in anterior regions with less evidence of changes in posterior regions. MA abusers have also shown deficits on attention tests that measure response conflict and cognitive control. Methods We examined cognitive control using a computerized measure of the Stroop selective attention task and indices of WM microstructure obtained from diffusion tensor imaging (DTI) in the callosal genu and splenium of 37 currently abstinent MA abusers and 17 non-substance abusing controls. Measurements of Fractional Anisotropy (FA), apparent diffusion coefficient (ADC) of callosal fibers and diffusion tensor eigenvalues were obtained in all subjects. Results The MA abusers exhibited greater Stroop reaction time interference (i.e., reduced cognitive control) [p=.04] compared to controls. After correcting for multiple comparisons, FA within the genu correlated significantly with measures of cognitive control in the MA abusers [p=.04, bonferroni corrected] but not in controls [p=.26]. Group differences in genu, but not splenium, FA were trend significant [p=.09]. Conclusions MA abuse appears to alter anterior callosal WM microstructure with less evidence of change within posterior callosal WM microstructure. DTI indices within the genu, but not splenium, correlated with measures of cognitive control in chronic MA abusers. PMID:18814867

  12. Evaluating Standards-Based Assessment Rubrics in a Postgraduate Public Health Subject

    Science.gov (United States)

    Kite, James; Phongsavan, Philayrath

    2017-01-01

    Standards-based assessment rubrics are recognised as an important tool for ensuring clear criteria in higher education. Most of the available evidence on rubrics comes from studies with face-to-face undergraduate students. Our study evaluated the introduction of rubrics into a postgraduate subject that included both online and face-to-face…

  13. Planck scale boundary conditions in the standard model with singlet scalar dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Haba, Naoyuki [Graduate School of Science and Engineering, Shimane University, Matsue, Shimane 690-8504 (Japan); Kaneta, Kunio [Kavli IPMU (WPI), The University of Tokyo, Kashiwa, Chiba 277-8568 (Japan); Takahashi, Ryo [Graduate School of Science and Engineering, Shimane University, Matsue, Shimane 690-8504 (Japan)

    2014-04-04

    We investigate Planck scale boundary conditions on the Higgs sector of the standard model with a gauge singlet scalar dark matter. We will find that vanishing self-coupling and Veltman condition at the Planck scale are realized with the 126 GeV Higgs mass and top pole mass, 172 GeV≲M{sub t}≲173.5 GeV, where a correct abundance of scalar dark matter is obtained with mass of 300 GeV≲m{sub S}≲1 TeV. It means that the Higgs potential is flat at the Planck scale, and this situation can not be realized in the standard model with the top pole mass.

  14. Subjectivity

    Directory of Open Access Journals (Sweden)

    Jesús Vega Encabo

    2015-11-01

    Full Text Available In this paper, I claim that subjectivity is a way of being that is constituted through a set of practices in which the self is subject to the dangers of fictionalizing and plotting her life and self-image. I examine some ways of becoming subject through narratives and through theatrical performance before others. Through these practices, a real and active subjectivity is revealed, capable of self-knowledge and self-transformation. 

  15. What Subject Matter Knowledge Do Second-Level Teachers Need to Know to Teach Trigonometry? An Exploration and Case Study

    Science.gov (United States)

    Walsh, Richard; Fitzmaurice, Olivia; O'Donoghue, John

    2017-01-01

    This study reports on the level of trigonometry Subject Matter Knowledge (SMK) of third and final-year pre-service second-level mathematics teachers () at an Irish third-level institution. The aim of the study was to determine if this sample of prospective teachers has an appropriate level of SMK to teach second-level trigonometric concepts. The…

  16. A Methodology for Investigating the Interactions of Individual Differences and Subject Matter Characteristics with Instructional Methods. ; Report 67.

    Science.gov (United States)

    Reigeluth, Charles M.

    This paper presents a general model for conceptualizing and testing the interactions of individual differences and subject-matter characteristics with instructional methods. The model postulates certain ways of classifying the variables of interest in such investigations and of conceptualizing the cause-and-effect relationships among those classes…

  17. Which One Is Better? Jigsaw II versus Jigsaw IV on the Subject of the Building Blocks of Matter and Atom

    Science.gov (United States)

    Turkmen, Hakan; Buyukaltay, Didem

    2015-01-01

    In this study, the effect of using Jigsaw II and Jigsaw IV techniques on the subject of "Atoms-The Basic Unit of Matter" in science course of 6th grade on academic achievement was examined. Pre-test post-test control group research was used in the study. Study population is all secondary schools in Turgutlu district of Manisa province…

  18. Reflective Pedagogy: The Integration of Methodology and Subject-Matter Content in a Graduate-Level Course

    Science.gov (United States)

    Jakeman, Rick C.; Henderson, Markesha M.; Howard, Lionel C.

    2017-01-01

    This article presents a critical reflection on how we, instructors of a graduate-level course in higher education administration, sought to integrate theoretical and subject-matter content and research methodology. Our reflection, guided by autoethnography and teacher reflection, challenged both our assumptions about curriculum design and our…

  19. The Knowledge Base of Subject Matter Experts in Teaching: A Case Study of a Professional Scientist as a Beginning Teacher

    Science.gov (United States)

    Diezmann, Carmel M.; Watters, James J.

    2015-01-01

    One method of addressing the shortage of science and mathematics teachers is to train scientists and other science-related professionals to become teachers. Advocates argue that as discipline experts these career changers can relate the subject matter knowledge to various contexts and applications in teaching. In this paper, through interviews and…

  20. Shared Knowledge among Graphic Designers, Instructional Designers and Subject Matter Experts in Designing Multimedia-Based Instructional Media

    Science.gov (United States)

    Razak, Rafiza Abdul

    2013-01-01

    The research identified and explored the shared knowledge among the instructional multimedia design and development experts comprising of subject matter expert, graphic designer and instructional designer. The knowledge shared by the team was categorized into three groups of multimedia design principles encompasses of basic principles, authoring…

  1. The Impact of Self-Perceived Subject Matter Knowledge on Pedagogical Decisions in EFL Grammar Teaching Practices

    Science.gov (United States)

    Sanchez, Hugo Santiago

    2014-01-01

    Recent developments in language teacher cognition research highlight the need to explore subject matter knowledge in relation to classroom practice. This study examines the impact of two foreign language teachers' knowledge about grammar upon their pedagogical decisions. The primary database consisted of classroom observations and post-lesson…

  2. The Effect of Applying Elements of Instructional Design on Teaching Material for the Subject of Classification of Matter

    Science.gov (United States)

    Ozdilek, Zehra; Ozkan, Muhlis

    2009-01-01

    The aim of this study was to examine the effect of instructional materials for the subject of classification of matter as solids, liquids and gases that were developed using a holistic instructional design model on student achievement. In the study a pre-test/post-test with control group experimental design was used. The study was conducted in the…

  3. Recurrence rate and subjective symptoms after standardized (Hamburg protocol) phototherapeutic keratectomy on recurrent corneal erosions.

    Science.gov (United States)

    Mehlan, J; Steinberg, J; Traber, L; Katz, T; Linke, S J

    2016-10-01

    To evaluate the objective and subjective outcome after phototherapeutic keratectomy (PTK) on recurrent corneal erosions (Hamburg protocol). For the standardized PTK according to Hamburg protocol a manual abrasio corneae performed with 20 % alcohol is followed by an excimer ablation depth of ≥15 μm (group1 15 μm; group 2 > 15 μm ablation depth) and 7 mm optical zone. All patients (N = 48) were invited for follow-up examinations and the evaluation of changes concerning subjective symptoms. A significantly reduced subjective impairment of night vision, significantly less pain and less foreign body sensations (for all p Hamburg Schema) is a safe and effective procedure to reduce subjective symptoms and improve discomfort in recurrent corneal erosion.

  4. Air Quality Standards for Particulate Matter (PM) at high altitude cities.

    Science.gov (United States)

    Bravo Alvarez, H; Sosa Echeverria, R; Sanchez Alvarez, P; Krupa, S

    2013-02-01

    The Air Quality Standards for Particulate Matter (PM) at high altitude urban areas in different countries, must consider the pressure and temperature due to the effect that these parameters have on the breath volume. This paper shows the importance to correct Air Quality Standards for PM considering pressure and temperature at different altitudes. Specific factors were suggested to convert the information concerning PM, from local to standard conditions, and adjust the Air Quality Standards for different high altitudes cities. The correction factors ranged from: 1.03 for Santiago de Chile to 1.47 for El Alto Bolivia. Other cities in this study include: Mexico City, México; La Paz, Bolivia; Bogota, Cali and Medellin, Colombia; Quito, Ecuador and Cuzco, Peru. If these corrections are not considered, the atmospheric concentrations will be underestimated. Copyright © 2012 Elsevier Ltd. All rights reserved.

  5. Resting state cortical electroencephalographic rhythms are related to gray matter volume in subjects with mild cognitive impairment and Alzheimer's disease.

    Science.gov (United States)

    Babiloni, Claudio; Carducci, Filippo; Lizio, Roberta; Vecchio, Fabrizio; Baglieri, Annalisa; Bernardini, Silvia; Cavedo, Enrica; Bozzao, Alessandro; Buttinelli, Carla; Esposito, Fabrizio; Giubilei, Franco; Guizzaro, Antonio; Marino, Silvia; Montella, Patrizia; Quattrocchi, Carlo C; Redolfi, Alberto; Soricelli, Andrea; Tedeschi, Gioacchino; Ferri, Raffaele; Rossi-Fedele, Giancarlo; Ursini, Francesca; Scrascia, Federica; Vernieri, Fabrizio; Pedersen, Torleif Jan; Hardemark, Hans-Goran; Rossini, Paolo M; Frisoni, Giovanni B

    2013-06-01

    Cortical gray matter volume and resting state cortical electroencephalographic rhythms are typically abnormal in subjects with amnesic mild cognitive impairment (MCI) and Alzheimer's disease (AD). Here we tested the hypothesis that in amnesic MCI and AD subjects, abnormalities of EEG rhythms are a functional reflection of cortical atrophy across the disease. Eyes-closed resting state EEG data were recorded in 57 healthy elderly (Nold), 102 amnesic MCI, and 108 AD patients. Cortical gray matter volume was indexed by magnetic resonance imaging recorded in the MCI and AD subjects according to Alzheimer's disease neuroimaging initiative project (http://www.adni-info.org/). EEG rhythms of interest were delta (2-4 Hz), theta (4-8 Hz), alpha1 (8-10.5 Hz), alpha2 (10.5-13 Hz), beta1 (13-20 Hz), beta2 (20-30 Hz), and gamma (30-40 Hz). These rhythms were indexed by LORETA. Compared with the Nold, the MCI showed a decrease in amplitude of alpha 1 sources. With respect to the Nold and MCI, the AD showed an amplitude increase of delta sources, along with a strong amplitude reduction of alpha 1 sources. In the MCI and AD subjects as a whole group, the lower the cortical gray matter volume, the higher the delta sources, the lower the alpha 1 sources. The better the score to cognitive tests the higher the gray matter volume, the lower the pathological delta sources, and the higher the alpha sources. These results suggest that in amnesic MCI and AD subjects, abnormalities of resting state cortical EEG rhythms are not epiphenomena but are strictly related to neurodegeneration (atrophy of cortical gray matter) and cognition. Copyright © 2011 Wiley Periodicals, Inc.

  6. Rhetorical meta-language to promote the development of students' writing skills and subject matter understanding

    Science.gov (United States)

    Pelger, Susanne; Sigrell, Anders

    2016-01-01

    students' understanding of their subject matter.

  7. Girl Scouts and Subject Matter Experts: What’s the Connection?

    Science.gov (United States)

    Harman, Pamela; Girls Scouts of Northern California, Girl Scouts USA, Astronomical Society of the Pacifica, Univeristy of Arizona, and ARIES Scientific.

    2018-01-01

    Reaching for the Stars: NASA Science for Girl Scouts (Girl Scout Stars) fosters interaction between Girl Scouts and NASA Subject Matter Experts (SMEs), disseminates NASA STEM education-related resources, and engages Girl Scouts in NASA science and programs through space science badges and summer camps.A space science badge is in development for each of the six levels of Girl Scouts: Daisies, Grades K – 1; Brownies, Grades 2 -3; Juniors, Grades 4 -5; Cadettes, Grades 6 -8; Seniors, Grades 9 -10; and Ambassadors, Grades 11 -12. Indirectly, SMEs will reach tens of thousands of girls through the badges. SETI Institute SMEs Institute and SME Co-Is located at ARIES Scientific, Astronomical Society of the Pacific, University of Arizona, and Girl Scouts of Northern California developed and modified astronomy activities for the Girl Scouts USA badge writers to finesse into the Girl Scout formats. Revisions are reviewed by SMEs for accuracy. Each badge includes a step option that encourages girls to connect with SMEs, and recommendations for volunteers.A total of 127 girls from 31 states and the District of Columbia attendedTotal Eclipse Destination Camps at three locations. SMEs led activities and tours, inspiring girls to consider STEM careers. University of Arizona (U of A) SMEs lead Astronomy Camp for Volunteers, enabling volunteers to lead and inspire Girl Scouts in their respective Girl Scout Councils. A Destination Camp for Girl Scouts was also held at U of A. Girls experience authentic astronomy, learning how to collect and analyze data.Eleven teams comprised of two Girl Scouts, a volunteer or Council Staff, and an amateur astronomer attended Astronomy Club Camp, held at NASA GSFC. SMEs delivered science content. The girls will lead the formation of astronomy clubs in their councils, and will train their successors. SMEs will present and coach the clubs during monthly webinars.This presentation will highlight success and discuss lessons learned that are applicable

  8. Subjective Video Quality Assessment in H.264/AVC Video Coding Standard

    Directory of Open Access Journals (Sweden)

    Z. Miličević

    2012-11-01

    Full Text Available This paper seeks to provide an approach for subjective video quality assessment in the H.264/AVC standard. For this purpose a special software program for the subjective assessment of quality of all the tested video sequences is developed. It was developed in accordance with recommendation ITU-T P.910, since it is suitable for the testing of multimedia applications. The obtained results show that in the proposed selective intra prediction and optimized inter prediction algorithm there is a small difference in picture quality (signal-to-noise ratio between decoded original and modified video sequences.

  9. Being in a romantic relationship is associated with reduced gray matter density in striatum and increased subjective happiness

    Directory of Open Access Journals (Sweden)

    Hiroaki Kawamichi

    2016-11-01

    Full Text Available Romantic relationship, a widespread feature of human society, is one of the most influential factors in daily life. Although stimuli related to romantic love or being in a romantic relationship commonly result in enhancement of activation or functional connectivity of the reward system, including the striatum, the structure underlying romantic relationship-related regions remain unclear. Because individual experiences can alter gray matter within the adult human brain, we hypothesized that romantic relationship is associated with structural differences in the striatum related to the positive subjective experience of being in a romantic relationship. Because intimate romantic relationships contribute to perceived subjective happiness, this subjective enhancement of happiness might be accompanied by the experience of positive events related to being in a romantic relationship. To test this hypothesis and elucidate the structure involved, we compared subjective happiness, an indirect measure of the existence of positive experiences caused by being in a romantic relationship, of participants with or without romantic partners (N = 68. Furthermore, we also conducted a voxel-based morphometry (VBM study of the effects of being in a romantic relationship (N = 113. Being in a romantic relationship was associated with greater subjective happiness and reduced gray matter density within the right dorsal striatum. These results suggest that being in a romantic relationship enhances perceived subjective happiness via positive experiences. Furthermore, the observed reduction in gray matter density in the right dorsal striatum may reflect an increase in saliency of social reward within a romantic relationship. Thus, being in a romantic relationship is associated with positive experiences and a reduction of gray matter density in the right dorsal striatum, representing a modulation of social reward.

  10. Being in a Romantic Relationship Is Associated with Reduced Gray Matter Density in Striatum and Increased Subjective Happiness.

    Science.gov (United States)

    Kawamichi, Hiroaki; Sugawara, Sho K; Hamano, Yuki H; Makita, Kai; Matsunaga, Masahiro; Tanabe, Hiroki C; Ogino, Yuichi; Saito, Shigeru; Sadato, Norihiro

    2016-01-01

    Romantic relationship, a widespread feature of human society, is one of the most influential factors in daily life. Although stimuli related to romantic love or being in a romantic relationship commonly result in enhancement of activation or functional connectivity of the reward system, including the striatum, the structure underlying romantic relationship-related regions remain unclear. Because individual experiences can alter gray matter within the adult human brain, we hypothesized that romantic relationship is associated with structural differences in the striatum related to the positive subjective experience of being in a romantic relationship. Because intimate romantic relationships contribute to perceived subjective happiness, this subjective enhancement of happiness might be accompanied by the experience of positive events related to being in a romantic relationship. To test this hypothesis and elucidate the structure involved, we compared subjective happiness, an indirect measure of the existence of positive experiences caused by being in a romantic relationship, of participants with or without romantic partners (N = 68). Furthermore, we also conducted a voxel-based morphometry study of the effects of being in a romantic relationship (N = 113). Being in a romantic relationship was associated with greater subjective happiness and reduced gray matter density within the right dorsal striatum. These results suggest that being in a romantic relationship enhances perceived subjective happiness via positive experiences. Furthermore, the observed reduction in gray matter density in the right dorsal striatum may reflect an increase in saliency of social reward within a romantic relationship. Thus, being in a romantic relationship is associated with positive experiences and a reduction of gray matter density in the right dorsal striatum, representing a modulation of social reward.

  11. Standardization of Connor-Davidson Resilience Scale in Iranian subjects with Cerebrovascular Accident

    Directory of Open Access Journals (Sweden)

    Seyed Alireza Derakhshanrad1

    2014-12-01

    Full Text Available Background: Resilience is a personal trait that can influence the stroke subjects’ attitudes toward future opportunities and facilitate the transitional process and adaptation in them. Assessment of this trait in stroke subjects with a standardized tool would promote the rehabilitation protocols and occupational therapy interventions. Therefore, the objective of this study was to standardize the Connor-Davidson Resilience Scale (CD-RISC for Persian Iranian people who have had strokes. Methods: A descriptive observational study was adopted in order to standardize the CD-RISC in stroke population. The population was comprised of 34 female and 29 male subjects with a mean age of 51.4±10.6 years and the history of ischemic or hemorrhagic cerebrovascular accidents. Subjects were recruited based on inclusion criteria within the period of two months between May and July of 2014. Descriptive statistics were calculated along with the Cronbach’s alpha to determine reliability. Standard multiple regression analyses searched for any correlation between variables and resilience. Results: Statistical parameters revealed a mean of 58.4±15.5 for CD-RISC raw scores. Percentile ranks were also calculated from raw data. Cronbach’s alpha of 0.892 revealed that the CD-RISC had high reliability for the population of this study. Multiple regression analyses showed that the functional status was the only variable that uniquely predicted subjects’ resilience (ß=0.41; P<0.01. Conclusion: The findings of this research confirmed applicability of CDRISC in Iranian people who have had strokes. The standardized CD-RISC was determined to be suitable for use in the clinic and for utilization in research studies in Iranian people status post-stroke.

  12. Direct detection of singlet dark matter in classically scale-invariant standard model

    Directory of Open Access Journals (Sweden)

    Kazuhiro Endo

    2015-10-01

    Full Text Available Classical scale invariance is one of the possible solutions to explain the origin of the electroweak scale. The simplest extension is the classically scale-invariant standard model augmented by a multiplet of gauge singlet real scalar. In the previous study it was shown that the properties of the Higgs potential deviate substantially, which can be observed in the International Linear Collider. On the other hand, since the multiplet does not acquire vacuum expectation value, the singlet components are stable and can be dark matter. In this letter we study the detectability of the real singlet scalar bosons in the experiment of the direct detection of dark matter. It is shown that a part of this model has already been excluded and the rest of the parameter space is within the reach of the future experiment.

  13. New constraints on dark matter effective theories from standard model loops.

    Science.gov (United States)

    Crivellin, Andreas; D'Eramo, Francesco; Procura, Massimiliano

    2014-05-16

    We consider an effective field theory for a gauge singlet Dirac dark matter particle interacting with the standard model fields via effective operators suppressed by the scale Λ ≳ 1 TeV. We perform a systematic analysis of the leading loop contributions to spin-independent Dirac dark matter-nucleon scattering using renormalization group evolution between Λ and the low-energy scale probed by direct detection experiments. We find that electroweak interactions induce operator mixings such that operators that are naively velocity suppressed and spin dependent can actually contribute to spin-independent scattering. This allows us to put novel constraints on Wilson coefficients that were so far poorly bounded by direct detection. Constraints from current searches are already significantly stronger than LHC bounds, and will improve in the near future. Interestingly, the loop contribution we find is isospin violating even if the underlying theory is isospin conserving.

  14. Planetary Exploration Education: As Seen From the Point of View of Subject Matter Experts

    Science.gov (United States)

    Milazzo, M. P.; Anderson, R. B.; Gaither, T. A.; Vaughan, R. G.

    2016-12-01

    Planetary Learning that Advances the Nexus of Engineering, Technology, and Science (PLANETS) was selected as one of 27 new projects to support the NASA Science Mission Directorate's Science Education Cooperative Agreement Notice. Our goal is to develop and disseminate out-of-school time (OST) curricular and related educator professional development modules that integrate planetary science, technology, and engineering. We are a partnership between planetary science Subject Matter Experts (SMEs), curriculum developers, science and engineering teacher professional development experts and OST teacher networks. The PLANETS team includes the Center for Science Teaching and Learning (CSTL) at Northern Arizona University (NAU); the U.S. Geological Survey (USGS) Astrogeology Science Center (Astrogeology), and the Boston Museum of Science (MOS). Here, we present the work and approach by the SMEs at Astrogeology. As part of this overarching project, we will create a model for improved integration of SMEs, curriculum developers, professional development experts, and educators. For the 2016 and 2017 Fiscal Years, our focus is on creating science material for two OST modules designed for middle school students. We will begin development of a third module for elementary school students in the latter part of FY2017. The first module focuses on water conservation and treatment as applied on Earth, the International Space Station, and at a fictional Mars base. This unit involves the science and engineering of finding accessible water, evaluating it for quality, treating it for impurities (i.e., dissolved and suspended), initial use, a cycle of greywater treatment and re-use, and final treatment of blackwater. The second module involves the science and engineering of remote sensing as it is related to Earth and planetary exploration. This includes discussion and activities related to the electromagnetic spectrum, spectroscopy and various remote sensing systems and techniques. In

  15. 40 CFR Appendix K to Part 50 - Interpretation of the National Ambient Air Quality Standards for Particulate Matter

    Science.gov (United States)

    2010-07-01

    ... Air Quality Standards for Particulate Matter K Appendix K to Part 50 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS NATIONAL PRIMARY AND SECONDARY AMBIENT AIR QUALITY STANDARDS Pt. 50, App. K Appendix K to Part 50—Interpretation of the National Ambient Air Quality Standards...

  16. Relevant Information and Informed Consent in Research: In Defense of the Subjective Standard of Disclosure.

    Science.gov (United States)

    Dranseika, Vilius; Piasecki, Jan; Waligora, Marcin

    2017-02-01

    In this article, we seek to contribute to the debate on the requirement of disclosure in the context of informed consent for research. We defend the subjective standard of disclosure and describe ways to implement this standard in research practice. We claim that the researcher should make an effort to find out what kinds of information are likely to be relevant for those consenting to research. This invites researchers to take empirical survey information seriously, attempt to understand the cultural context, talk to patients to be better able to understand what can be potentially different concerns and interests prevalent in the target population. The subjective standard of disclosure should be seen as a moral ideal that perhaps can never be perfectly implemented but still can and should be used as a normative ideal guiding research practice. In the light of these discussions, we call for more empirical research on what considerations are likely to be perceived as relevant by potential research participants recruited from different socio-economic and cultural groups.

  17. Right-handed neutrino dark matter in a U(1) extension of the Standard Model

    Science.gov (United States)

    Cox, Peter; Han, Chengcheng; Yanagida, Tsutomu T.

    2018-01-01

    We consider minimal U(1) extensions of the Standard Model in which one of the right-handed neutrinos is charged under the new gauge symmetry and plays the role of dark matter. In particular, we perform a detailed phenomenological study for the case of a U(1)(B‑L)3 flavoured B‑L symmetry. If perturbativity is required up to high-scales, we find an upper bound on the dark matter mass of mχlesssim2 TeV, significantly stronger than that obtained in simplified models. Furthermore, if the U(1)(B‑L)3 breaking scalar has significant mixing with the SM Higgs, there are already strong constraints from direct detection. On the other hand, there remains significant viable parameter space in the case of small mixing, which may be probed in the future via LHC Z' searches and indirect detection. We also comment on more general anomaly-free symmetries consistent with a TeV-scale RH neutrino dark matter candidate, and show that if two heavy RH neutrinos for leptogenesis are also required, one is naturally led to a single-parameter class of U(1) symmetries.

  18. Integrating Multicultural Subject Matters into Teaching Strategies of Elementary School Teachers (The U.S. State of Kansas

    Directory of Open Access Journals (Sweden)

    Stanka Lunder Verlič

    2014-12-01

    Full Text Available The following academic article is based on a PhD thesis that is currently being completed, titled Education and Qualifications of Elementary School Teachers in the U.S. State of Kansas and Slovenia for teaching in classes with immigrant children. The research study titled Integrating Multicultural Subject Matters into Teaching Strategies of Elementary School Teachers (The U.S. State of Kansas, conducted in 2007 based on a sample of 89 elementary school teachers in the U.S. State of Kansas, represents one aspect of assessing the adequacy of undergraduate education regarding multicultural subject matters for elementary school teachers in Slovenia and the U.S. (State of Kansas as well as the qualifications of elementary school teachers of both countries for working with immigrant children. Despite the long-standing tradition of multicultural education in western countries, the research results for Kansas elementary school teachers showed a presence of significant discrepancies between the actual and optimal integration of multicultural subject matters. These results indicate that future undergraduate study programs will have to invest more time in developing multicultural skills and providing practical experiences for working in a diverse environment.

  19. Beanblock® (standardized dry extract of Phaseolus vulgaris) in mildly overweight subjects: a pilot study.

    Science.gov (United States)

    Luzzi, R; Belcaro, G; Hu, S; Dugall, M; Hosoi, M; Ippolito, E; Corsi, M; Gizzi, G

    2014-10-01

    This study evaluates the efficacy of Beanblock®, a standardized extract of Phaseolus vulgaris L., on weight control in healthy overweight subjects on a weight management plan that combined lifestyle and dietary advice. Sixty overweight (BMI 25-30 kg/m2) healthy subjects were enroled. All subjects were instructed to follow a weight management plan, accompanied by dietary advice. Thirty subjects used Beanblock® for at least 12 weeks (50 mg tablets, two times daily). The remaining 30 subjects did not receive any supplementation (management-only). The main endpoints were changes in body weight and waist circumference, with plasmatic oxidative stress, satiey and appetite being also evaluated. At week 12, the supplementation with Beanblock® was associated with a reduction in body weight (from 82.8 ± 9.1 kg to 78.8 ± 8.9 kg; p < 0.0001) and a decrease of waist circumference from 94.4 ± 10.3 cm to 88.2 ± 10.0 cm (p < 0.0001). Conversely, only marginal changes were observed in the control group. Oxidative stress was also significantly decreased with Beanblock® (from 380.4 ± 14.8 to 340.7 ± 14.8 Carr Units; p < 0.0001). Satiety and appetite improved in the supplement group. No side effects were observed and compliance was optimal. Beanblock®, in association with a health management plan, was useful for weight control in mildly overweight healthy subjects.

  20. Can the relic density of self-interacting dark matter be due to annihilations into Standard Model particles?

    Energy Technology Data Exchange (ETDEWEB)

    Chu, Xiaoyong [International Centre for Theoretical Physics, ICTP,Strada Costiera 11, Trieste, 34014 (Italy); Garcia-Cely, Camilo; Hambye, Thomas [Service de Physique Théorique, Université Libre de Bruxelles,Boulevard du Triomphe, CP225, Brussels, 1050 (Belgium)

    2016-11-08

    Motivated by the hypothesis that dark matter self-interactions provide a solution to the small-scale structure formation problems, we investigate the possibilities that the relic density of a self-interacting dark matter candidate can proceed from the thermal freeze-out of annihilations into Standard Model particles. We find that scalar and Majorana dark matter in the mass range of 10–500 MeV, coupled to a slightly heavier massive gauge boson, are the only possible candidates in agreement with multiple current experimental constraints. Here dark matter annihilations take place at a much slower rate than the self-interactions simply because the interaction connecting the Standard Model and the dark matter sectors is small. We also discuss prospects of establishing or excluding these two scenarios in future experiments.

  1. Subject Matter Expert Evaluation of Multi-Flight Common Route Advisories

    Science.gov (United States)

    Bilimoria, Karl D.; Hayashi, Miwa; Sheth, Kapil

    2017-01-01

    manager finds the advisory to be operationally appropriate, he or she would coordinate with the Area Supervisor(s) of the sectors that currently control the flights in the advisory. When the traffic manager accepts the MFCR advisory via the user interface, the corresponding flight plan amendments would be sent to the displays of the appropriate sector controllers, using the Airborne Re-Routing (ABRR) capability which is scheduled for nationwide operation in 2017. The sector controllers would then offer this time-saving route modification to the pilots of the affected flights via datalink (or voice), and implement the corresponding flight plan amendment if the pilots accept it. MFCR is implemented as an application in the software environment of the Future Air traffic management Concepts Evaluation Tool (FACET). This paper focuses on an initial subject matter expert (SME) evaluation of MFCR. The evaluation covers MFCRs operational concept, algorithm, and user interface.

  2. 49 CFR Appendix A to Part 541 - Light Duty Truck Lines Subject to the Requirements of This Standard

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Light Duty Truck Lines Subject to the Requirements of This Standard A Appendix A to Part 541 Transportation Other Regulations Relating to Transportation... VEHICLE THEFT PREVENTION STANDARD Pt. 541, App. A Appendix A to Part 541—Light Duty Truck Lines Subject to...

  3. Subjective Video Quality Assessment of H.265 Compression Standard for Full HD Resolution

    Directory of Open Access Journals (Sweden)

    Miroslav Uhrina

    2015-01-01

    Full Text Available Recently increasing interest in multimedia services leads to requirements for quality assessment, especially in the video domain. There are many factors that influence the video quality. Compression technology and transmission link imperfection can be considered as the main ones. This paper deals with the assessment of the impact of H.265/HEVC compression standard on the video quality using subjective metrics. The evaluation is done for two types of sequences with Full HD resolution depending on content. The paper is divided as follows. In the first part of the article, a short characteristic of the H.265/HEVC compression standard is written. In the second part, the subjective video quality methods used in our experiments are described. The last part of this article deals with the measurements and experimental results. They showed that quality of sequences coded between 5 and 7 Mbps is for observers sufficient, so there is no need for providers to use higher bitrates in streaming than this threshold. These results are part of a new model that is still being created and will be used for predicting the video quality in networks based on IP.

  4. Reducing the Standard Deviation in Multiple-Assay Experiments Where the Variation Matters but the Absolute Value Does Not

    Science.gov (United States)

    Echenique-Robba, Pablo; Nelo-Bazán, María Alejandra; Carrodeguas, José A.

    2013-01-01

    When the value of a quantity for a number of systems (cells, molecules, people, chunks of metal, DNA vectors, so on) is measured and the aim is to replicate the whole set again for different trials or assays, despite the efforts for a near-equal design, scientists might often obtain quite different measurements. As a consequence, some systems’ averages present standard deviations that are too large to render statistically significant results. This work presents a novel correction method of a very low mathematical and numerical complexity that can reduce the standard deviation of such results and increase their statistical significance. Two conditions are to be met: the inter-system variations of matter while its absolute value does not, and a similar tendency in the values of must be present in the different assays (or in other words, the results corresponding to different assays must present a high linear correlation). We demonstrate the improvements this method offers with a cell biology experiment, but it can definitely be applied to any problem that conforms to the described structure and requirements and in any quantitative scientific field that deals with data subject to uncertainty. PMID:24205158

  5. Perturbative extension of the standard model with a 125 GeV Higgs and Magnetic Dark Matter

    DEFF Research Database (Denmark)

    Dissauer, Karin; Frandsen, Mads Toudal; Hapola, Tuomas

    2012-01-01

    We introduce a perturbative extension of the standard model featuring a new dark matter sector together with a 125 GeV Higgs. The new sector consists of a vector-like heavy electron E, a complex scalar electron S and a standard model singlet Dirac fermion \\chi. The interactions among the dark...

  6. Common Core State Standards for English Language Arts & Literacy in History/Social Studies, Science, and Technical Subjects

    Science.gov (United States)

    Common Core State Standards Initiative, 2010

    2010-01-01

    The Common Core State Standards for English Language Arts & Literacy in History/Social Studies, Science, and Technical Subjects ("the Standards") are the culmination of an extended, broad-based effort to fulfill the charge issued by the states to create the next generation of K-12 standards in order to help ensure that all students…

  7. Bromatological composition and dry matter digestibility of millet cultivars subjected to nitrogen doses

    Directory of Open Access Journals (Sweden)

    W.H.D. Buso

    2014-06-01

    Full Text Available The bromatological composition and in vitro dry matter digestibility of millet cultivars were assessed for different nitrogen doses and two sowing seasons in the Ceres municipality of Goiás state, Brazil. The treatments consisted of three millet cultivars (ADR-7010, ADR-500 and BRS-1501, four nitrogen (N doses (0, 50, 100 and 200kg ha-1 of N and two sowing seasons. Three replicates and a randomised block design with a 3 x 4 x 2 factorial scheme were used. Two cuttings were performed in each season when plants reached an average height of 0.70 cm. No significant interactions were observed between or among cultivars for N doses and dry matter (DM, crude protein (CP, neutral detergent fibre (NDF and acid detergent fibre (ADF contents. The DM, CP, NDF and ADF contents were significantly different between N doses. The DM and CP contents increased as the N dose increased to 100kg ha-1. The maximum DM and CP contents were 11.14 and 22.53%, respectively. The NDF and ADF contents were higher in the control treatment (60.11 and 30.01%, respectively. In addition, the lowest ADF and NDF concentrations occurred at an N dose of 50kg ha-1 (56.33 and 30.23%, respectively. The DM contents were higher for the February sowing, with an average of 10.59%. The highest CP and ADF contents were found for the December sowing (22.46 and 31.58%, respectively. No significant differences were found for millet cultivars, N doses or sowing seasons. A significant interaction was found between sowing season and millet cultivar. The BRS-1501 cultivar had a higher in vitro dry matter digestibility in the December/2010 sowing (73.88%.

  8. New Constraints on Dark Matter Effective Theories from Standard Model Loops

    CERN Document Server

    Crivellin, Andreas; Procura, Massimiliano

    2014-01-01

    We consider an effective field theory for a gauge singlet Dirac dark matter (DM) particle interacting with the Standard Model (SM) fields via effective operators suppressed by the scale $\\Lambda \\gtrsim 1$ TeV. We perform a systematic analysis of the leading loop contributions to spin-independent (SI) DM--nucleon scattering using renormalization group evolution between $\\Lambda$ and the low-energy scale probed by direct detection experiments. We find that electroweak interactions induce operator mixings such that operators that are naively velocity-suppressed and spin-dependent can actually contribute to SI scattering. This allows us to put novel constraints on Wilson coefficients that were so far poorly bounded by direct detection. Constraints from current searches are comparable to LHC bounds, and will significantly improve in the near future. Interestingly, the loop contribution we find is maximally isospin violating even if the underlying theory is isospin conserving.

  9. Individualized Gaussian process-based prediction and detection of local and global gray matter abnormalities in elderly subjects.

    Science.gov (United States)

    Ziegler, G; Ridgway, G R; Dahnke, R; Gaser, C

    2014-08-15

    Structural imaging based on MRI is an integral component of the clinical assessment of patients with potential dementia. We here propose an individualized Gaussian process-based inference scheme for clinical decision support in healthy and pathological aging elderly subjects using MRI. The approach aims at quantitative and transparent support for clinicians who aim to detect structural abnormalities in patients at risk of Alzheimer's disease or other types of dementia. Firstly, we introduce a generative model incorporating our knowledge about normative decline of local and global gray matter volume across the brain in elderly. By supposing smooth structural trajectories the models account for the general course of age-related structural decline as well as late-life accelerated loss. Considering healthy subjects' demography and global brain parameters as informative about normal brain aging variability affords individualized predictions in single cases. Using Gaussian process models as a normative reference, we predict new subjects' brain scans and quantify the local gray matter abnormalities in terms of Normative Probability Maps (NPM) and global z-scores. By integrating the observed expectation error and the predictive uncertainty, the local maps and global scores exploit the advantages of Bayesian inference for clinical decisions and provide a valuable extension of diagnostic information about pathological aging. We validate the approach in simulated data and real MRI data. We train the GP framework using 1238 healthy subjects with ages 18-94 years, and predict in 415 independent test subjects diagnosed as healthy controls, Mild Cognitive Impairment and Alzheimer's disease. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

  10. A common NTRK2 variant is associated with emotional arousal and brain white-matter integrity in healthy young subjects

    Science.gov (United States)

    Spalek, K; Coynel, D; Freytag, V; Hartmann, F; Heck, A; Milnik, A; de Quervain, D; Papassotiropoulos, A

    2016-01-01

    Dysregulation of emotional arousal is observed in many psychiatric diseases such as schizophrenia, mood and anxiety disorders. The neurotrophic tyrosine kinase receptor type 2 gene (NTRK2) has been associated with these disorders. Here we investigated the relation between genetic variability of NTRK2 and emotional arousal in healthy young subjects in two independent samples (n1=1171; n2=707). In addition, diffusion tensor imaging (DTI) data in a subgroup of 342 participants were used to identify NTRK2-related white-matter structure differences. After correction for multiple testing, we identified a NTRK2 single nucleotide polymorphism associated with emotional arousal in both samples (n1: Pnominal=0.0003, Pcorrected=0.048; n2: Pnominal=0.0141, Pcorrected=0.036). DTI revealed significant, whole-brain corrected correlations between emotional arousal and brain white-matter mean diffusivity (MD), as well as significant, whole-brain corrected NTRK2 genotype-related differences in MD (PFWE<0.05). Our study demonstrates that genetic variability of NTRK2, a susceptibility gene for psychiatric disorders, is related to emotional arousal and—independently—to brain white-matter properties in healthy individuals. PMID:26978740

  11. A common NTRK2 variant is associated with emotional arousal and brain white-matter integrity in healthy young subjects.

    Science.gov (United States)

    Spalek, K; Coynel, D; Freytag, V; Hartmann, F; Heck, A; Milnik, A; de Quervain, D; Papassotiropoulos, A

    2016-03-15

    Dysregulation of emotional arousal is observed in many psychiatric diseases such as schizophrenia, mood and anxiety disorders. The neurotrophic tyrosine kinase receptor type 2 gene (NTRK2) has been associated with these disorders. Here we investigated the relation between genetic variability of NTRK2 and emotional arousal in healthy young subjects in two independent samples (n1=1171; n2=707). In addition, diffusion tensor imaging (DTI) data in a subgroup of 342 participants were used to identify NTRK2-related white-matter structure differences. After correction for multiple testing, we identified a NTRK2 single nucleotide polymorphism associated with emotional arousal in both samples (n1: Pnominal=0.0003, Pcorrected=0.048; n2: Pnominal=0.0141, Pcorrected=0.036). DTI revealed significant, whole-brain corrected correlations between emotional arousal and brain white-matter mean diffusivity (MD), as well as significant, whole-brain corrected NTRK2 genotype-related differences in MD (PFWEemotional arousal and-independently-to brain white-matter properties in healthy individuals.

  12. Relationship between mathematics teacher subject matter knowledge, pedagogical content knowledge and professional development needs

    Science.gov (United States)

    Tajudin, Nor'ain Mohd; Chinnappan, Mohan; Saad, Noor Shah

    2017-05-01

    Two key variables emerged from the literature review is that Specific Matter Knowledge [SMK] and Pedagogical Content Knowledge [PCK] can influence the mathematics teachers' Professional Development [PD] needs. However, the key variables of SMK and PCK that were being investigated were not defined clearly. Empirical evidence that support relationship between SMK and PD and PCK and PD were not verified. In addition, how does PCK mediate SMK and PD is not clear and somewhat lacking. Therefore, the purpose of this paper was to examine the relationship between primary mathematics teacher's SMK, PCK and PD needs. Results of path analysis with SmartPLS indicated that the direct effect of SMK on PD was mediated via PCK. This data provide support for the claim that PD programs for future teachers of primary mathematics should be driven by a more nuanced understanding of the link between SMK and PCK.

  13. The Role of Reading Comprehension in Large-Scale Subject-Matter Assessments

    Science.gov (United States)

    Zhang, Ting

    2013-01-01

    This study was designed with the overall goal of understanding how difficulties in reading comprehension are associated with early adolescents' performance in large-scale assessments in subject domains including science and civic-related social studies. The current study extended previous research by taking a cognition-centered approach based on…

  14. Subjective Evaluations of Alcohol-Related Consequences among College Students: Experience with Consequences Matters

    Science.gov (United States)

    Leavens, Eleanor L.; Leffingwell, Thad R.; Miller, Mary Beth; Brett, Emma I.; Lombardi, Nathaniel

    2017-01-01

    Objective: Research suggests college students rate some alcohol-related consequences less negatively than others, yet it is unclear how or when these differences in perception develop. The current study compared college students' subjective evaluations of alcohol-related consequences that they had and had not experienced in order to test the…

  15. Implications of right-handed neutrinos in B -L extended standard model with scalar dark matter

    Science.gov (United States)

    Bandyopadhyay, Priyotosh; Chun, Eung Jin; Mandal, Rusa

    2018-01-01

    We investigate the standard model (SM) with a U (1 )B-L gauge extension where a B -L charged scalar is a viable dark matter (DM) candidate. The dominant annihilation process, for the DM particle is through the B -L symmetry breaking scalar to a right-handed neutrino pair. We exploit the effect of decay and inverse decay of the right-handed neutrino in thermal relic abundance of the DM. Depending on the values of the decay rate, the DM relic density can be significantly different from what is obtained in the standard calculation assuming the right-handed neutrino is in thermal equilibrium and there appear different regions of the parameter space satisfying the observed DM relic density. For a DM mass less than O (TeV ) , the direct detection experiments impose a competitive bound on the mass of the U (1 )B-L gauge boson Z' with the collider experiments. Utilizing the nonobservation of the displaced vertices arising from the right-handed neutrino decays, the bound on the mass of Z' has been obtained at present and higher luminosities at the LHC with 14 TeV center of mass energy where an integrated luminosity of 100 fb-1 is sufficient to probe mZ'˜5.5 TeV .

  16. Academic Literacies and Adolescent Learners: English for Subject-Matter Secondary Classrooms

    Science.gov (United States)

    Enright, Kerry Anne

    2010-01-01

    Comprehensive high schools are extremely complex sites for the teaching and learning of academic literacies. However, current policy mandates emphasizing standards and accountability mask this complexity. Legislation such as No Child Left Behind in the United States and similar initiatives in other countries narrow the curriculum through their…

  17. Naturalness and dark matter in the supersymmetric B -L extension of the standard model

    Science.gov (United States)

    Delle Rose, Luigi; Khalil, Shaaban; King, Simon J. D.; Marzo, Carlo; Moretti, Stefano; Un, Cem S.

    2017-09-01

    We study the naturalness properties of the B -L supersymmetric standard model (BLSSM) with type-I seesaw and compare them to those of the minimal supersymmetric standard model (MSSM) at both low (i.e., Large Hadron Collider) energies and high (i.e., unification) scales. By adopting standard measures of naturalness, we assess that, in the presence of full unification of the additional gauge couplings and scalar/fermionic masses of the BLSSM, such a scenario reveals a somewhat higher degree of fine-tuning (FT) than the MSSM, when the latter is computed at the unification scale and all available theoretical and experimental constraints, but the dark matter (DM) ones, are taken into account. Yet, such a difference, driven primarily by the collider limits requiring a high mass for the gauge boson associated to the breaking of the additional U (1 )B -L gauge group of the BLSSM in addition to the S U (3 )C×S U (2 )L×U (1 )Y of the MSSM, should be regarded as a modest price to pay for the former in relation to the latter, if one notices that the nonminimal scenario offers a significant volume of parameter space where numerous DM solutions of different compositions can be found to the relic density constraints, unlike the case of the minimal structure, wherein only one type of solution is accessible over an ever diminishing parameter space. In fact, this different level of tension within the two SUSY models in complying with current data is well revealed when the FT measure is recomputed in terms of the low-energy spectra of the two models, over their allowed regions of parameter space now in the presence of all DM bounds, as it is shown that the tendency is now opposite, with the BLSSM appearing more natural than the MSSM.

  18. Relative activity of cerebral subcortical gray matter in varying states of attention and awareness in normal subjects and patient studies

    Energy Technology Data Exchange (ETDEWEB)

    Cooper, M.; Chen, C.T.; Levy, J.; Wagner, N.; Spire, J.P.; Jacobsen, J.; Meltzer, H.; Metz, J.; Beck, R.N.

    1985-05-01

    An important aspect of the study of brain function involves measurement of the relationships; between activities in the subcortical gray matter of the caudate and of the thalamus; and between these structures and functional cortical areas. The authors have studied these relationships in 22 subjects under different conditions of activation, sleep and sensory deprivation using a PET VI system and F-18-2DG to determine regional cerebral metabolism. Subject activating conditions were maintained throughout the period of equilibration of F-18-2DG and E.E.G.'s were monitored. Multiple tomographic slices of 1-2 million counts were obtained simultaneously with slice separation of 14mm and each plane parallel to the cantho-meatal line. In activated and non-activated awake conditions for normal subjects, left and right thalmus-to-caudate ratios were similar and greater than unity. This relationship was maintained in non-REM sleep, but was reversed and divergent in REM sleep and sensory deprivation; this was also evident in 3/4 narcoleptics awake and asleep in non-REM and REM and 2/3 schizophrenics and affective disorder, subjects. This approach appears to have potential for characterizating normal and disordered regional cerebral function.

  19. Concentration dynamics and biodegradability of dissolved organic matter in wetland soils subjected to experimental warming.

    Science.gov (United States)

    Wang, Hang; Holden, Joseph; Zhang, Zhijian; Li, Meng; Li, Xia

    2014-02-01

    Dissolved organic matter (DOM) is the most bioavailable soil organic pool. Understanding how DOM responds to elevated temperature is important for forecasting soil carbon (C) dynamics under climate warming. Here a 4.5-year field microcosm experiment was carried out to examine temporal DOM concentration dynamics in soil pore-water from six different subtropical wetlands. Results are compared between control (ambient temperature) and warmed (+5°C) treatments. UV-visible and fluorescence spectroscopy was performed to reveal DOM structural complexity at the end of the warming incubation. Elevated temperature resulted in initially (1 to 2.5 years) high pore-water DOM concentrations in warmed samples. These effects gradually diminished over longer time periods. Of the spectral indices, specific UV absorbance at 280 nm and humification index were significantly higher, while the signal intensity ratio of the fulvic-like to humic-like fluorescence peak was lower in warmed samples, compared to the control. Fluorescence regional integration analysis further suggested that warming enhanced the contribution of humic-like substances to DOM composition for all tested wetlands. These spectral fingerprints implied a declined fraction of readily available substrates in DOM allocated to microbial utilization in response to 4.5 years of warming. As a negative feedback, decreased DOM biodegradability may have the potential to counteract initial DOM increases and alleviate C loss in water-saturated wetland soils. © 2013.

  20. Early kinetic decoupling of dark matter: When the standard way of calculating the thermal relic density fails

    Science.gov (United States)

    Binder, Tobias; Bringmann, Torsten; Gustafsson, Michael; Hryczuk, Andrzej

    2017-12-01

    Calculating the abundance of thermally produced dark matter particles has become a standard procedure, with sophisticated methods guaranteeing a precision that matches the percent-level accuracy in the observational determination of the dark matter density. Here, we point out that one of the main assumptions in the commonly adopted formalism, namely local thermal equilibrium during the freeze-out of annihilating dark matter particles, does not have to be satisfied in general. We present two methods for how to deal with such situations, in which the kinetic decoupling of dark matter happens so early that it interferes with the chemical decoupling process: (i) an approximate treatment in terms of a coupled system of differential equations for the leading momentum moments of the dark matter distribution, and (ii) a full numerical solution of the Boltzmann equation in phase space. For illustration, we apply these methods to the case of scalar singlet dark matter. We explicitly show that even in this simple model the prediction for the dark matter abundance can be affected by up to 1 order of magnitude compared to the traditional treatment.

  1. Organizational Context Matters: A Research Toolkit for Conducting Standardized Case Studies of Integrated Care Initiatives

    Directory of Open Access Journals (Sweden)

    Jenna M. Evans

    2017-06-01

    Full Text Available Introduction: The variable success of integrated care initiatives has led experts to recommend tailoring design and implementation to the organizational context. Yet, organizational contexts are rarely described, understood, or measured with sufficient depth and breadth in empirical studies or in practice. We thus lack knowledge of when and specifically how organizational contexts matter. To facilitate the accumulation of evidence, we developed a research toolkit for conducting case studies using standardized measures of the (inter-organizational context for integrating care.  Theory and Methods: We used a multi-method approach to develop the research toolkit: (1 development and validation of the Context and Capabilities for Integrating Care (CCIC Framework, (2 identification, assessment, and selection of survey instruments, (3 development of document review methods, (4 development of interview guide resources, and (5 pilot testing of the document review guidelines, consolidated survey, and interview guide.  Results: The toolkit provides a framework and measurement tools that examine 18 organizational and inter-organizational factors that affect the implementation and success of integrated care initiatives.  Discussion and Conclusion: The toolkit can be used to characterize and compare organizational contexts across cases and enable comparison of results across studies. This information can enhance our understanding of the influence of organizational contexts, support the transfer of best practices, and help explain why some integrated care initiatives succeed and some fail.

  2. How to foster student-student learning of science? The student, the teacher and the subject matter

    Science.gov (United States)

    Bianchini, Julie A.

    2011-12-01

    In this response to Konstantinos Alexakos, Jayson K. Jones, and Victor H. Rodriguez's study, I discuss ways attending to student membership in groups can both inform research on equity and diversity in science education and improve the teaching of science to all students. My comments are organized into three sections: how underrepresented students' experiences in science classrooms are shaped by their peers; how science teachers can help students listen to and learn from one another; and how the subject matter can invite or discourage student participation in science. More specifically, I underscore the need for teachers and students to listen to one another to promote student learning of science. I also highlight the importance of science education researchers and science teachers viewing students both as individuals and as members of multiple groups; women of color, for example, should be understood as similar to and different from each other, from European American women and from ethnic minorities in general.

  3. Viable dark matter via radiative symmetry breaking in a scalar singlet Higgs portal extension of the standard model.

    Science.gov (United States)

    Steele, T G; Wang, Zhi-Wei; Contreras, D; Mann, R B

    2014-05-02

    We consider the generation of dark matter mass via radiative electroweak symmetry breaking in an extension of the conformal standard model containing a singlet scalar field with a Higgs portal interaction. Generating the mass from a sequential process of radiative electroweak symmetry breaking followed by a conventional Higgs mechanism can account for less than 35% of the cosmological dark matter abundance for dark matter mass M(s)>80 GeV. However, in a dynamical approach where both Higgs and scalar singlet masses are generated via radiative electroweak symmetry breaking, we obtain much higher levels of dark matter abundance. At one-loop level we find abundances of 10%-100% with 106 GeVdark matter mass. The dynamical approach also predicts a small scalar-singlet self-coupling, providing a natural explanation for the astrophysical observations that place upper bounds on dark matter self-interaction. The predictions in all three approaches are within the M(s)>80 GeV detection region of the next generation XENON experiment.

  4. Elevated leukocyte count in asymptomatic subjects is associated with a higher risk for cerebral white matter lesions.

    Science.gov (United States)

    Kim, Chi Kyung; Lee, Seung-Hoon; Kim, Beom Joon; Ryu, Wi-Sun; Choi, Seung Ho; Oh, Byung-Hee; Yoon, Byung-Woo

    2011-04-01

    Cerebral white matter lesions (WMLs) are radiologic markers of small vessel disease in brain, and inflammatory processes were related to WMLs. We propose to determine if elevated leukocyte count was associated with a higher risk of WMLs. 1586 asymptomatic subjects who visited our hospital for a routine health check-up were enrolled. Leukocyte counts were measured and the presence of moderate to severe WMLs was determined by brain MRI. Thirty (1.9%) had moderate to severe WMLs, and a significant greater proportion (4.1%) of subjects in the highest leukocyte count quartile had moderate to severe WMLs. After adjusting by C-reactive protein, aspirin use and cardiovascular risk factors, the highest quartile of leukocyte count (≥6.7×10⁹/L) was significantly associated with moderate to severe WMLs compared with the lowest quartile [adjusted odds ratio, 4.03; 95% confidence interval, 1.05-15.5]. The authors report for the first time that an elevated leukocyte count is independently associated with moderate to severe WMLs. Copyright © 2010. Published by Elsevier B.V.

  5. Right-handed neutrino dark matter in the classically conformal U(1 ) ' extended standard model

    Science.gov (United States)

    Oda, Satsuki; Okada, Nobuchika; Takahashi, Dai-suke

    2017-11-01

    We consider the dark matter (DM) scenario in the context of the classically conformal U(1 ) ' extended standard model (SM), with three right-handed neutrinos (RHNs) and the U(1 ) ' Higgs field. The model is free from all of the U(1 ) ' gauge and gravitational anomalies in the presence of the three RHNs. We introduce a Z2 parity in the model, under which an odd parity is assigned to one RHN, while all of the other particles are assigned to be Z2 even, and hence the Z2-odd RHN serves as a DM candidate. In this model, the U(1 ) ' gauge symmetry is radiatively broken through the Coleman-Weinberg mechanism, by which the electroweak symmetry breaking is triggered. There are three free parameters in our model—the U(1 ) ' charge of the SM Higgs doublet (xH ), the new U(1 ) ' gauge coupling (gX ), and the U(1 ) ' gauge boson (Z') mass (mZ')—which are severely constrained in order to solve the electroweak vacuum instability problem, and satisfy the LHC Run-2 bounds from the search for the Z' boson resonance. In addition to these constraints, we investigate the RHN DM physics. Because of the nature of classical conformality, we find that a RHN DM pair mainly annihilates into the SM particles through Z' boson exchange. This is the so-called Z'-portal DM scenario. Combining the electroweak vacuum stability condition, the LHC Run-2 bounds, and the cosmological constraint from the observed DM relic density, we find that all constraints work together to narrow the allowed parameter regions and, in particular, exclude mZ'≲3.5 TeV . For the obtained allowed regions, we calculate the spin-independent cross section of the RHN DM with nucleons. We find that the resultant cross section is well below the current experimental upper bounds.

  6. CTEPP STANDARD OPERATING PROCEDURE FOR DAY CARE CENTER SAMPLE SUBJECTS RECRUITMENT (SOP-1.11)

    Science.gov (United States)

    The CTEPP subject recruitment procedures for the daycare center component are described in the SOP. There are two stages in this phase of CTEPP subject recruitment. The objective of the first stage is to enroll daycare centers for the study. Six target counties in each state ar...

  7. NPY mRNA Expression in the Prefrontal Cortex: Selective Reduction in the Superficial White Matter of Subjects with Schizoaffective Disorder

    Science.gov (United States)

    Morris, Harvey M.; Stopczynski, Rachelle E.; Lewis, David A.

    2009-01-01

    Background Alterations in the inhibitory circuitry of the dorsolateral prefrontal cortex (DLPFC) in schizophrenia include reduced expression of the messenger RNA (mRNA) for somatostatin (SST), a neuropeptide present in a subpopulation of γ-aminobutyric acid (GABA) neurons. Neuropeptide Y (NPY) is expressed in a subset of SST-containing interneurons and lower levels of NPY mRNA have also been reported in schizophrenia spectrum disorders. However, whether the alterations in these two transcripts identify the same, particularly vulnerable, subset of GABA neurons has not been examined. Methods We used in situ hybridization to quantify NPY mRNA levels in DLPFC gray and white matter from 23 pairs of subjects with schizophrenia or schizoaffective disorder and matched normal control subjects; results were compared to those from a previous study of SST mRNA expression in the same subjects. Results In contrast to SST mRNA, NPY mRNA levels were not significantly lower in the gray matter of subjects with schizophrenia or schizoaffective disorder. However, NPY, but not SST, mRNA expression was significantly lower in the superficial white matter of subjects with schizoaffective disorder. Conclusion These findings suggest that the alterations in SST-containing interneurons in schizophrenia and schizoaffective disorder are selective for the subset that do not express NPY mRNA, and that lower NPY mRNA expression in the superficial white matter may distinguish subjects with schizoaffective disorder from those with schizophrenia. PMID:19804960

  8. 75 FR 65567 - Approval and Promulgation of Air Quality Implementation Plans; Ohio; Particulate Matter Standards

    Science.gov (United States)

    2010-10-26

    ... have been necessary to attain and maintain the 2006 National Ambient Air Quality Standards (NAAQS) for.... B. OAC 3745-17-02--Ambient Air Quality Standards The ambient air quality standards for PM in Rule 2... air quality standards were made as strict as Federal standards and the incorporation by reference...

  9. The Subject's Matter

    DEFF Research Database (Denmark)

    in the significance of the body in our mental life. The sixteen specially commissioned essays in this book reflect the advances in these fields. The book is divided into three parts, each part covering a topic central to an explanation of bodily self-awareness: representation of the body; the sense of bodily......The body may be the object we know the best. It is the only object from which we constantly receive a flow of information through sight and touch; and it is the only object we can experience from the inside, through our proprioceptive, vestibular, and visceral senses. Yet there have been very few...... books that have attempted to consolidate our understanding of the body as it figures in our experience and self-awareness. This volume offers an interdisciplinary and comprehensive treatment of bodily self-awareness, the first book to do so since the landmark 1995 collection The Body and the Self...

  10. Common Core State Standards for Literacy in History/Social Studies, Science, and Technical Subjects for English Language Learners

    Science.gov (United States)

    de Oliveira, Luciana C., Ed.

    2016-01-01

    This volume in the Common Core State Standards (CCSS) for English Language Learners series was designed to deepen teacher's knowledge and provides instructional approaches and practices for supporting grades 6-12 ELLs as they meet the ambitious expectations of the CCSS for Literacy in History/Social Studies, Science, and Technical Subjects. This…

  11. The Three-Level Synthesis of Standardized Single-Subject Experimental Data: A Monte Carlo Simulation Study.

    Science.gov (United States)

    Moeyaert, Mariola; Ugille, Maaike; Ferron, John M; Beretvas, S Natasha; Van den Noortgate, Wim

    2013-09-01

    Previous research indicates that three-level modeling is a valid statistical method to make inferences from unstandardized data from a set of single-subject experimental studies, especially when a homogeneous set of at least 30 studies are included ( Moeyaert, Ugille, Ferron, Beretvas, & Van den Noortgate, 2013a ). When single-subject data from multiple studies are combined, however, it often occurs that the dependent variable is measured on a different scale, requiring standardization of the data before combining them over studies. One approach is to divide the dependent variable by the residual standard deviation. In this study we use Monte Carlo methods to evaluate this approach. We examine how well the fixed effects (e.g., immediate treatment effect and treatment effect on the time trend) and the variance components (the between- and within-subject variance) are estimated under a number of realistic conditions. The three-level synthesis of standardized single-subject data is found appropriate for the estimation of the treatment effects, especially when many studies (30 or more) and many measurement occasions within subjects (20 or more) are included and when the studies are rather homogeneous (with small between-study variance). The estimates of the variance components are less accurate.

  12. DNA as patentable subject matter and a narrow framework for addressing the perceived problems caused by gene patents.

    Science.gov (United States)

    Schilling, Stephen H

    2011-12-01

    Concerns about the alleged harmful effects of gene patents--including hindered research and innovation and impeded patient access to high-quality genetic diagnostic tests--have resulted in overreactions from the public and throughout the legal profession. These overreactions are exemplified by Association for Molecular Pathology v. U.S. Patent and Trademark Office, a 2010 case in the Southern District of New York that held that isolated DNA is unpatentable subject matter under 35 U.S.C. § 101. The problem with these responses is that they fail to adequately consider the role that gene patents and patents on similar biomolecules play in facilitating investment in the costly and risky developmental processes required to transform the underlying inventions into marketable products. Accordingly, a more precisely refined solution is advisable. This Note proposes a narrowly tailored set of solutions to address the concerns about gene patents without destroying the incentives for companies to create and commercialize inventions derived from these and similar patents.

  13. Developing Pedagogical Content Knowledge for Teaching a New Topic: More Than Teaching Experience and Subject Matter Knowledge

    Science.gov (United States)

    Chan, Kennedy Kam Ho; Yung, Benny Hin Wai

    2017-03-01

    Teaching experience has been identified as an important factor in pedagogical content knowledge (PCK) development. However, little is known about how experienced teachers may draw on their previous experience to facilitate their PCK development. This study examined how two experienced high school biology teachers approached the teaching of a newly introduced topic in the curriculum, polymerase chain reaction and their PCK development from the pre-lesson planning phase through the interactive phase to the post-lesson reflection phase. Multiple data sources included classroom observations, field notes, semi-structured interviews and classroom artefacts. It was found that the teachers' previous experience informed their planning for teaching the new topic, but in qualitatively different ways. This, in turn, had a bearing on their new PCK development. Subject matter knowledge (SMK) can not only facilitate but may also hinder this development. Our findings identify two types of experienced teachers: those who can capitalise on their previous teaching experiences and SMK to develop new PCK and those who do not. The critical difference is whether in the lesson planning stage, the teacher shows the disposition to draw on a generalised mental framework that enables the teacher to capitalise on his existing SMK to develop new PCK. Helping teachers to acquire this disposition should be a focus for teacher training in light of continuous curriculum changes.

  14. The effect of productive classroom talk and metacommunication on young children's oral communicative competence and subject matter knowledge: An intervention study in early childhood education

    NARCIS (Netherlands)

    van der Veen, C.; de Mey, J.R.P.B.; van Kruistum, C.J.; van Oers, B.

    The aim of the present study was to investigate the effect of productive classroom talk and metacommunication on the development of young children's oral communicative competence and subject matter knowledge. This study can be characterized as a quasi-experimental study with a

  15. A Case Study of Beginning Science Teachers' Subject Matter (SMK) and Pedagogical Content Knowledge (PCK) of Teaching Chemical Reaction in Turkey

    Science.gov (United States)

    Usak, Muhammet; Ozden, Mustafa; Eilks, Ingo

    2011-01-01

    This paper describes a case study focusing on the subject matter knowledge, pedagogical content knowledge, and beliefs about science teaching of student teachers in Turkey at the start of their university education. The topic of interest was that of teaching chemical reactions in secondary chemistry education. A written test was developed which…

  16. Exploring the Relationship between Secondary Science Teachers' Subject Matter Knowledge and Knowledge of Student Conceptions While Teaching Evolution by Natural Selection

    Science.gov (United States)

    Lucero, Margaret M.; Petrosino, Anthony J.; Delgado, Cesar

    2017-01-01

    The fundamental scientific concept of evolution occurring by natural selection is home to many deeply held alternative conceptions and considered difficult to teach. Science teachers' subject matter knowledge (SMK) and the pedagogical content knowledge (PCK) component of knowledge of students' conceptions (KOSC) can be valuable resources for…

  17. Is Practical Subject Matter Knowledge Still Important? Examining the Siedentopian Perspective on the Role of Content Knowledge in Physical Education Teacher Education

    Science.gov (United States)

    Herold, Frank; Waring, Michael

    2017-01-01

    Background: The role that content knowledge, an important component of practical subject matter knowledge, plays for pre-service teachers (PSTs) in physical education teacher education (PETE) remains contested and unclear. Whilst some researchers emphasise the facilitative nature of such knowledge, others criticise that too much focus on content…

  18. Does Variation in the Extent of Generalized Trust, Individual Education and Extensiveness of Social Security Policies Matter for Maximization of Subjective Well-Being?

    Science.gov (United States)

    Valeeva, Rania F.

    2016-01-01

    In this paper, I examine whether generalized trust and education, as well as social security policies of welfare state institutions matter for cross-national differences in subjective well-being (SWB), because knowledge on this issue is still lacking. For this purpose I integrated the insights of two sociological theories: Social Function…

  19. The Examination of Secondary Education Chemistry Curricula Published between 1957-2007 in Terms of the Dimensions of Rationale, Goals, and Subject-Matter

    Science.gov (United States)

    Pekdag, Bulent; Erol, Hilal

    2013-01-01

    Fifteen secondary education chemistry curricula published from 1957 until 2007 were examined based on the dimensions of rationale, goals, and subject matter. An examination of documents in the scope of qualitative research was carried out in the study. The goals included in the examined chemistry curricula were analyzed according to the cognitive,…

  20. Personality profiles between obese and control subjects assessed with five standardized personality scales.

    Science.gov (United States)

    López-Pantoja, José L; Cabranes, José A; Sanchez-Quintero, Sabrina; Velao, Manuel; Sanz, Montserrat; Torres-Pardo, Beatriz; Ancín, Inés; Cabrerizo, Lucio; Rubio, Miguel A; Lopez-Ibor, Juan J; Barabash, Ana

    2012-01-01

    Psychopathology may exert influence on developing and maintaining obesity. Studies of personality traits or psychopathology of personality in obesity are scarce and contradictory. The aim of this study was to compare personality profiles between obese and normal-weight subjects and to determine the most useful tool to detect differences, considering that psychological assessment and psychotherapeutical support should be included within the overall management of these patients.* We examined 55 obese subjects (mean BMI=43kg/ m2) and 66 controls (mean BMI =21.7kg/m2). We used the personality assessment tools: MCMI-II, TCI-R, EPQ-A, BIS-111 and SSS. Factorial multivariate analysis of variance was applied; with factors BMI, Gender and Age as a covariate. Significant differences between groups were more marked in the clinical syndrome scales of MCMI-II, particularly in Major-Depression, Thought-Disorder, Anxiety, Somatoform and Alcohol-Dependence. Among obese, women scored higher than men in all scales but not significantly. We have found significant differences in normal personality dimensions between both groups in TCI-R. Obese showed higher scores in Harm Avoidance, and lower in Novelty Seeking, Persistence and Self-transcendence. The remaining tests have not been useful for differentiating personality traits between both groups. Obese subjects showed different personality profiles than control subjects. The most useful scales for determining these differences might be those designed to assess pathological personality such as MCMI-II. Less important would be those intended to measure normal personality traits, such as TCI-R and EPQ-A.

  1. Technical comments on EPA`s proposed revisions to the National Ambient Air Quality Standard for particulate matter

    Energy Technology Data Exchange (ETDEWEB)

    Lipfert, F.W.

    1997-03-01

    The US Environmental Protection Agency (EPA) has proposed new ambient air quality standards specifically for fine particulate matter, regulating concentrations of particles with median aerodynamic diameters less than 2.5 {mu}m (PM{sub 2.5}). Two new standards have been proposed: a maximum 24-hr concentration that is intended to protect against acute health effects, and an annual concentration limit that is intended to protect against longer-term health effects. EPA has also proposed a slight relaxation of the 24-hr standard for inhalable particles (PM{sub 10}), by allowing additional exceedances each year. Fine particles are currently being indirectly controlled by means of regulations for PM{sub 10} and TSP, under the Clean Air Act of 1970 and subsequent amendments. Although routine monitoring of PM{sub 2.5} is rare and data are sparse, the available data indicate that ambient concentrations have been declining at about 6% per year under existing regulations.

  2. Implications of direct dark matter constraints for minimal supersymmetric standard model Higgs boson searches at the Tevatron.

    Science.gov (United States)

    Carena, Marcela; Hooper, Dan; Skands, Peter

    2006-08-04

    In regions of large tanbeta and small mAlpha, searches for heavy neutral minimal supersymmetric standard model (MSSM) Higgs bosons at the Tevatron are promising. At the same time, rates in direct dark matter experiments, such as CDMS, are enhanced in the case of large tanbeta and small mAlpha. As a result, there is a natural interplay between the heavy, neutral Higgs searches at the Tevatron and the region of parameter space explored by CDMS. We show that if the lightest neutralino makes up the dark matter of our universe, current limits from CDMS strongly constrain the prospects of heavy, neutral MSSM Higgs discovery at the Tevatron unless |mu| greater or approximately 400 GeV. The limits of CDMS projected for 2007 will increase this constraint to |mu| greater or approximately 800 GeV. If CDMS does observe neutralinos in the near future, however, it will make the discovery of Higgs bosons at the Tevatron far more likely.

  3. CosmoQuest: Supporting Subject Matter Experts in Broadening the Impacts of their Work beyond their Institutional Walls.

    Science.gov (United States)

    Noel-Storr, J.; Buxner, S.; Grier, J.; Gay, P.

    2016-12-01

    CosmoQuest is a virtual research facility, which, like its physical counterparts, provides tools for scientists to acquire reduced data products (thanks to our cadre of citizen scientists working to analyze images and produce results online), and also to participate in education and outreach activities either directly through CosmoQuest activities (such as CosmoAcademy and the Educators' Zone) or with the support of CosmoQuest. Here, we present our strategies to inspire, engage and support Subject Matter Experts (SMEs - Scientists, Engineers, Technologists and Mathematicians) in activities outside of their institutions, and beyond college classroom teaching. We provide support for SMEs who are interested in increasing the impacts of their science knowledge and expertise by interacting with people online, or in other venues outside of their normal work environment. This includes a broad spectrum of opportunities for those interested in hosting webinars; running short courses for the public; using Facebook, Twitter or other social media to communicate science; or other diverse activities such as supporting an open house, science fair, or star party. As noted by Katheryn Woods-Townsend and colleagues, "...face-to-face interactions with scientists allowed students to view scientists as approachable and normal people, and to begin to understand the range of scientific areas and careers that exist. Scientists viewed the scientist-student interactions as a vehicle for science communication" (2015). As CosmoQuest fosters these relationships, it We present a framework for SMEs which combine opportunities for continuing professional development (virtually and in person at conferences) with ongoing online support, creating a dynamic professional learning network. The goal of this is to deepen SME capacity-knowledge, attitudes and behaviors-both encouraging and empowering them to connect to broader audiences in new ways.

  4. Beyond standard quality of life measures: the subjective experiences of living with inflammatory bowel disease.

    Science.gov (United States)

    Wolfe, Barat J; Sirois, Fuschia M

    2008-08-01

    In order to facilitate our understanding of health-related quality of life (HRQoL) for inflammatory bowel disease (IBD) patients, it is critical to explore their subjective experiences with the disease. Research has suggested that current modes of assessing HRQoL (i.e., generic and disease-specific measures) may not fully represent all dimensions of patients' HRQoL. The purpose of this study was to examine IBD patients' subjective experiences of the daily impact of IBD, and categorize dimensions of their HRQoL affected by IBD, as identified by the patients themselves. Two hundred and eighty-two patients with IBD provided answers to the qualitative question "How has IBD affected your daily activities?" A content analysis using NVivo 2.0 was conducted on the participants' responses to this question to reveal dimensions of their HRQoL. The analysis yielded six dimensions and several subdimensions of HRQoL, including physical (systemic functioning, daily functioning, energy/vitality, pain), emotional, social, cognitive (functioning, attending to disease), self-regulation (taking control, loss of control, and neutral), and practical functioning. These results reflect previous findings, but also reveal several dimensions of HRQoL not included in current measures of HRQoL for IBD patients (i.e., cognitive, self-regulation, and practical). The implications of these findings for future measurement of HRQoL and research with IBD patients are discussed.

  5. [Design of standard voice sample text for subjective auditory perceptual evaluation of voice disorders].

    Science.gov (United States)

    Li, Jin-rang; Sun, Yan-yan; Xu, Wen

    2010-09-01

    To design a speech voice sample text with all phonemes in Mandarin for subjective auditory perceptual evaluation of voice disorders. The principles for design of a speech voice sample text are: The short text should include the 21 initials and 39 finals, this may cover all the phonemes in Mandarin. Also, the short text should have some meanings. A short text was made out. It had 155 Chinese words, and included 21 initials and 38 finals (the final, ê, was not included because it was rarely used in Mandarin). Also, the text covered 17 light tones and one "Erhua". The constituent ratios of the initials and finals presented in this short text were statistically similar as those in Mandarin according to the method of similarity of the sample and population (r = 0.742, P text were statistically not similar as those in Mandarin (r = 0.731, P > 0.05). A speech voice sample text with all phonemes in Mandarin was made out. The constituent ratios of the initials and finals presented in this short text are similar as those in Mandarin. Its value for subjective auditory perceptual evaluation of voice disorders need further study.

  6. Imprints of non-standard dark energy and dark matter models on the 21cm intensity map power spectrum

    Science.gov (United States)

    Carucci, Isabella P.; Corasaniti, Pier-Stefano; Viel, Matteo

    2017-12-01

    We study the imprint of non-standard dark energy (DE) and dark matter (DM) models on the 21cm intensity map power spectra from high-redshift neutral hydrogen (HI) gas. To this purpose we use halo catalogs from N-body simulations of dynamical DE models and DM scenarios which are as successful as the standard Cold Dark Matter model with Cosmological Constant (ΛCDM) at interpreting available cosmological observations. We limit our analysis to halo catalogs at redshift z=1 and 2.3 which are common to all simulations. For each catalog we model the HI distribution by using a simple prescription to associate the HI gas mass to N-body halos. We find that the DE models leave a distinct signature on the HI spectra across a wide range of scales, which correlates with differences in the halo mass function and the onset of the non-linear regime of clustering. In the case of the non-standard DM model significant differences of the HI spectra with respect to the ΛCDM model only arise from the suppressed abundance of low mass halos. These cosmological model dependent features also appear in the 21cm spectra. In particular, we find that future SKA measurements can distinguish the imprints of DE and DM models at high statistical significance.

  7. Location of lacunar infarcts correlates with cognition in a sample of non-disabled subjects with age-related white-matter changes: the LADIS study

    DEFF Research Database (Denmark)

    Benisty, S; Gouw, A A; Porcher, R

    2009-01-01

    in the following areas: lobar white matter, putamen/pallidum, thalamus, caudate nucleus, internal/external capsule, infratentorial areas. An analysis of covariance was performed after adjustment for possible confounders. RESULTS: Among 633 subjects, 47% had at least one lacune (31% at least one within basal...... a significant negative association between the presence of lacunes in putamen/pallidum and the memory compound Z score (beta = -0.13; p = 0.038). By contrast, no significant negative association was found between cognitive parameters and the presence of lacunes in internal capsule, lobar white matter...

  8. Attitudes towards Study Effort Response to Higher Grading Standards: Do Gender and Personality Distinctions Matter?

    Science.gov (United States)

    Fallan, Lars; Opstad, Leiv

    2012-01-01

    The purpose of this paper is to explore how gender and personality preferences affect student attitudes towards effort response to higher grading standards. Data collected from 150 economics and business students at a Scandinavian business school reveals that higher grading standards enhance effort and time devoted to learning to a higher degree…

  9. 78 FR 21850 - Federal Motor Vehicle Safety Standards; Matters Incorporated by Reference

    Science.gov (United States)

    2013-04-12

    ... National Highway Traffic Safety Administration 49 CFR Part 571 RIN 2127-AL25 Federal Motor Vehicle Safety... references to the many standards and practices that are incorporated by reference into the Federal motor... motor vehicle safety standards (FMVSSs) in 49 CFR Part 571 (Part 571).\\1\\ Although this part already...

  10. 45 CFR 73.735-1304 - Referral of matters arising under the standards of this part.

    Science.gov (United States)

    2010-10-01

    ... under the standards of this part. (a) The Department Ethics Counselor may refer to the Inspector General... Department Ethics Counselor may refer to the Office of Government Ethics, or the Inspector General may refer to the Department of Justice, suspected violations of the criminal laws regarding employee standards...

  11. Reporting ethical matters in the Journal of Physiology: standards and advice.

    Science.gov (United States)

    Drummond, Gordon B

    2009-02-15

    Reporting of ethical matters in The Journal is very important. To advise and assist authors, particularly those who may be less familiar with the legislation in the UK, this article sets out the basic principles and methods that should be used and provides many key web sources of information. It addresses the structure of regulations, and introduces the concept of research governance. The UK law is summarized. Advice is given on the format and description of experiments, and common problems addressed. Aspects of human studies are addressed. Ethical considerations of publication such as authorship and originality, and problems such as plagiarism and fabrication are described. Updates will be published regularly.

  12. Environmental effectiveness of GAEC cross-compliance standard 2.2 "Maintaining the level of soil organic matter through crop rotation" and economic evaluation of the competitiveness gap for farmers

    Directory of Open Access Journals (Sweden)

    Lamberto Borrelli

    2015-11-01

    Full Text Available Within the Project MO.NA.CO was evaluated the Environmental effectiveness of GAEC cross-compliance standard 2.2 “Maintaining the level of soil organic matter through crop rotation” and economic evaluation of the competitiveness gap for farmers who support or not the cross-compliance regime. The monitoring was performed in nine experimental farms of the Council for Agricultural Research and Economics (CREA distributed throughout Italy and with different soil and climatic conditions. Were also evaluated the soil organic matter and some yield parameters, in a cereal monocropping (treatment counterfactual and a two-year rotation cereal-legume or forage (treatment factual. The two-years application of the standard “crop rotations” has produced contrasting results with regards to the storage of soil organic matter through crop rotation and these were not sufficient to demonstrate a statistically significant effect of treatment in any of the farms considered in monitoring, only in those farms subjected to more years of monitoring was recorded only a slight effect of the standard as a trend. The variations of organic matter in soils in response to changes in the culture technique or in the management of the soil may have long lag times and two years of time are not sufficient to demonstrate the dynamics of SOM associated with the treatment, also in consideration of the large inter annual variability recorded in different monitored sites.

  13. 2006 Particulate Matter (PM) National Ambient Air Quality Standards (NAAQS) Infrastructure Actions

    Science.gov (United States)

    Read about the EPA's infrastructure actions for the 2006 PM NAAQS. These actions are regarding states' failure to submit SIPs addressing various parts of the standards. Here you can read the federal register notices,and fact sheets

  14. An investigation into the validity of cervical spine motion palpation using subjects with congenital block vertebrae as a 'gold standard'

    Directory of Open Access Journals (Sweden)

    Peterson Cynthia K

    2004-06-01

    Full Text Available Abstract Background Although the effectiveness of manipulative therapy for treating back and neck pain has been demonstrated, the validity of many of the procedures used to detect joint dysfunction has not been confirmed. Practitioners of manual medicine frequently employ motion palpation as a diagnostic tool, despite conflicting evidence regarding its utility and reliability. The introduction of various spinal models with artificially introduced 'fixations' as an attempt to introduce a 'gold standard' has met with frustration and frequent mechanical failure. Because direct comparison against a 'gold standard' allows the validity, specificity and sensitivity of a test to be calculated, the identification of a realistic 'gold standard' against which motion palpation can be evaluated is essential. The objective of this study was to introduce a new, realistic, 'gold standard', the congenital block vertebra (CBV to assess the validity of motion palpation in detecting a true fixation. Methods Twenty fourth year chiropractic students examined the cervical spines of three subjects with single level congenital block vertebrae, using two commonly employed motion palpation tests. The examiners, who were blinded to the presence of congenital block vertebrae, were asked to identify the most hypomobile segment(s. The congenital block segments included two subjects with fusion at the C2–3 level and one with fusion at C5-6. Exclusion criteria included subjects who were frankly symptomatic, had moderate or severe degenerative changes in their cervical spines, or displayed signs of cervical instability. Spinal levels were marked on the subject's skin overlying the facet joints from C1 to C7 bilaterally and the motion segments were then marked alphabetically with 'A' corresponding to C1-2. Kappa coefficients (K were calculated to determine the validity of motion palpation to detect the congenitally fused segments as the 'most hypomobile' segments. Sensitivity

  15. Maintaining standards of aesthetic practice in trainees subject to NHS restrictions.

    Science.gov (United States)

    Paterson, P; Allison, K

    2006-01-01

    The Specialist Advisory Committee (SAC) in plastic surgery within the United Kingdom (UK) recommends a modular training programme to include aesthetic surgery. The intercollegiate board examinations test candidates on all aspects of aesthetic practice yet there is no formal, national aesthetic training in the UK. Closure of National Health Service (NHS) private patient facilities has reduced training opportunity [Nicolle FV. Sir Harold Gillies Memorial Lecture; Aesthetic plastic surgery and the future plastic surgeon. Br J Plast Surg 1998;51:419-24.] Calmanisation [Hospital doctors: training for the future. The Report of the Working Group on Specialist Medical Training (The Calman Report). London: HMSO; 1993.], the European Working Time Directive (EWTD) [; Phillips H, Fleet Z, Bowman K. The European Working time Directive-interim report and guidance from The Royal College of Surgeons of England working party chaired by Mr Hugh Phillips; 2003 []; Chesser S, Bowman K, Phillips H. The European Working Time Directive and the training of surgeons. BMJ Careers Focus 2002;s69-7.], and more importantly the implementation of "local" aesthetic guidelines have placed further pressures on training. Reductions of NHS case mix will ultimately lead to a reduction in trainee experience. With increasing regulatory pressure from the Commission for Healthcare Improvement, standards of aesthetic practice can only be maintained by increasing private/independent sector involvement. At present a disparity exists between the demand and provision of aesthetic surgery training in the UK. Aesthetic surgery forms part of the training curriculum for plastic surgery and as such remains a training issue. A review of aesthetic surgery training is needed in the UK through consultation with trainers and trainee representatives.

  16. Perfection of methods of training to the technics of throws and catching of gymnastic subject matters at a stage of special base preparation.

    Directory of Open Access Journals (Sweden)

    Andreeva N.O.

    2011-08-01

    Full Text Available The analysis of performances gymnasts at competitions of a different level shows, that the system of training in rhythmic gymnastics at a stage of special-purpose base preparation requires entering of the corrective amendments which have been directed on perfection of its forms and procedures. One of such innovations may be use in training process of innovative methods of perfection of work on gymnastic subject matters. In article initial theoretical positions and ways of perfection of process of training to throws and catching of a ball and other subject matters as basic means of progress at gymnasts impellent qualities and the skills necessary for achievement of high results in competitive activity are considered.

  17. 77 FR 38889 - National Ambient Air Quality Standards for Particulate Matter

    Science.gov (United States)

    2012-06-29

    ... the data handling procedures consistent with the proposed primary and secondary standards for PM 2.5... proposes to make revisions to the primary and secondary NAAQS for PM to provide requisite protection of... Primary Annual PM 2.5 NAAQS in Nonattainment Areas D. Implementing the Primary and Secondary PM 10 NAAQS E...

  18. Sustainability in Science Education? How the Next Generation Science Standards Approach Sustainability, and Why It Matters

    Science.gov (United States)

    Feinstein, Noah Weeth; Kirchgasler, Kathryn L.

    2015-01-01

    In this essay, we explore how sustainability is embodied in the Next Generation Science Standards (NGSS), analyzing how the NGSS explicitly define and implicitly characterize sustainability. We identify three themes (universalism, scientism, and technocentrism) that are common in scientific discourse around sustainability and show how they appear…

  19. Standardization of a computerized method for calculating autonomic function test responses in healthy subjects and patients with diabetes mellitus

    Directory of Open Access Journals (Sweden)

    C. Neumann

    1997-02-01

    Full Text Available The objectives of the present study were 1 to compare results obtained by the traditional manual method of measuring heart rate (HR and heart rate response (HRR to the Valsalva maneuver, standing and deep breathing, with those obtained using a computerized data analysis system attached to a standard electrocardiograph machine; 2 to standardize the responses of healthy subjects to cardiovascular tests, and 3 to evaluate the response to these tests in a group of patients with diabetes mellitus (DM. In all subjects (97 healthy and 143 with DM we evaluated HRR to deep breathing, HRR to standing, HRR to the Valsalva maneuver, and blood pressure response (BPR to standing up and to a sustained handgrip. Since there was a strong positive correlation between the results obtained with the computerized method and the traditional method, we conclude that the new method can replace the traditional manual method for evaluating cardiovascular responses with the advantages of speed and objectivity. HRR and BPR of men and women did not differ. A correlation between age and HRR was observed for standing (r = -0.48, P<0.001 and deep breathing (r = -0.41, P<0.002. Abnormal BPR to standing was usually observed only in diabetic patients with definite and severe degrees of autonomic neuropathy.

  20. The effect of match standard and referee experience on the objective and subjective match workload of English Premier League referees.

    Science.gov (United States)

    Weston, M; Bird, S; Helsen, W; Nevill, A; Castagna, C

    2006-06-01

    The aim of the present study was to examine the effect of match standard and referee experience on the objective and subjective workload of referees during English Premier League and Football League soccer matches. We also examined the relationship between heart rate (HR) and ratings of perceived exertion (RPE) for assessing match intensity in soccer referees. Heart rate responses were recorded using short-range telemetry and RPE scores were collected using a 10-point scale. Analysis revealed a significant relationship between mean match HR and match RPE scores (r=0.485, pFootball League 81.5+/-2.2%HRmax, pFootball League 6.9+/-0.8, pReferee experience had no effect on match HR and RPE responses to Premier League and Football League matches. The results of the present study demonstrate the validity of using HR and RPE as a measure of global match intensity in soccer referees. Referee experience had no effect on the referees' objective and subjective match workload assessments, whereas match intensity was correlated to competition standard. These findings have implications for fitness preparation and evaluation in soccer referees. When progressing to a higher level of competition, referees should ensure that appropriate levels of fitness are developed in order to enable them to cope with an increase in physical match demands.

  1. Improving LMA predictions with non-standard interactions: neutrino decay in solar matter?

    CERN Document Server

    Das, C R

    2010-01-01

    It has been known for some time that the well established LMA solution to the observed solar neutrino deficit fails to predict a flat energy spectrum for SuperKamiokande as opposed to what the data indicates. It also leads to a Chlorine rate which appears to be too high as compared to the data. We investigate the possible solution to these inconsistencies with non standard neutrino interactions, assuming that they come as extra contributions to the $\

  2. Conformal complex singlet extension of the Standard Model: scenario for dark matter and a second Higgs boson

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Zhi-Wei; Steele, T.G. [Department of Physics and Engineering Physics, University of Saskatchewan,116 Science Place, Saskatoon, SK, S7N 5E2 (Canada); Hanif, T. [Department of Theoretical Physics, University of Dhaka,Dhaka-1000 (Bangladesh); Mann, R.B. [Department of Physics, University of Waterloo,Waterloo, ON, N2L 3G1 (Canada)

    2016-08-09

    We consider a conformal complex singlet extension of the Standard Model with a Higgs portal interaction. The global U(1) symmetry of the complex singlet can be either broken or unbroken and we study each scenario. In the unbroken case, the global U(1) symmetry protects the complex singlet from decaying, leading to an ideal cold dark matter candidate with approximately 100 GeV mass along with a significant proportion of thermal relic dark matter abundance. In the broken case, we have developed a renormalization-scale optimization technique to significantly narrow the parameter space and in some situations, provide unique predictions for all the model’s couplings and masses. We have found there exists a second Higgs boson with a mass of approximately 550 GeV that mixes with the known 125 GeV Higgs with a large mixing angle sin θ≈0.47 consistent with current experimental limits. The imaginary part of the complex singlet in the broken case could provide axion dark matter for a wide range of models. Upon including interactions of the complex scalar with an additional vector-like fermion, we explore the possibility of a diphoton excess in both the unbroken and the broken cases. In the unbroken case, the model can provide a natural explanation for diphoton excess if extra terms are introduced providing extra contributions to the singlet mass. In the broken case, we find a set of coupling solutions that yield a second Higgs boson of mass 720 GeV and an 830 GeV extra vector-like fermion F, which is able to address the 750 GeV LHC diphoton excess. We also provide criteria to determine the symmetry breaking pattern in both the Higgs and hidden sectors.

  3. Development of two fine particulate matter standard reference materials (<4 μm and <10 μm) for the determination of organic and inorganic constituents.

    Science.gov (United States)

    Schantz, Michele M; Cleveland, Danielle; Heckert, N Alan; Kucklick, John R; Leigh, Stefan D; Long, Stephen E; Lynch, Jennifer M; Murphy, Karen E; Olfaz, Rabia; Pintar, Adam L; Porter, Barbara J; Rabb, Savelas A; Vander Pol, Stacy S; Wise, Stephen A; Zeisler, Rolf

    2016-06-01

    Two new Standard Reference Materials (SRMs), SRM 2786 Fine Particulate Matter (Particulate Matter (particulate matter (PM). These materials have been characterized for the mass fractions of selected polycyclic aromatic hydrocarbons (PAHs), nitrated PAHs, brominated diphenyl ether (BDE) congeners, hexabromocyclododecane (HBCD) isomers, sugars, polychlorinated dibenzo-p-dioxin (PCDD) and dibenzofuran (PCDF) congeners, and inorganic constituents, as well as particle-size characteristics. These materials are the first Certified Reference Materials available to support measurements of both organic and inorganic constituents in fine PM. In addition, values for PAHs are available for RM 8785 Air Particulate Matter on Filter Media. As such, these SRMs will be useful as quality control samples for ensuring compatibility of results among PM monitoring studies and will fill a void to assess the accuracy of analytical methods used in these studies. Graphical Abstract Removal of PM from filter for the preparation of SRM 2786 Fine Particulate Matter.

  4. Being in a romantic relationship is associated with reduced gray matter density in striatum and increased subjective happiness

    OpenAIRE

    Hiroaki Kawamichi; Sugawara, Sho K.; Hamano, Yuki H.; Kai Makita; Masahiro Matsunaga; Tanabe, Hiroki C.; Yuichi Ogino; Shigeru Saito; Norihiro Sadato

    2016-01-01

    Romantic relationship, a widespread feature of human society, is one of the most influential factors in daily life. Although stimuli related to romantic love or being in a romantic relationship commonly result in enhancement of activation or functional connectivity of the reward system, including the striatum, the structure underlying romantic relationship-related regions remain unclear. Because individual experiences can alter gray matter within the adult human brain, we hypothesized that ro...

  5. Being in a Romantic Relationship Is Associated with Reduced Gray Matter Density in Striatum and Increased Subjective Happiness

    OpenAIRE

    Kawamichi, Hiroaki; Sugawara, Sho K.; Hamano, Yuki H.; Makita, Kai; Matsunaga, Masahiro; Tanabe, Hiroki C.; Ogino, Yuichi; Saito, Shigeru; Sadato, Norihiro

    2016-01-01

    Romantic relationship, a widespread feature of human society, is one of the most influential factors in daily life. Although stimuli related to romantic love or being in a romantic relationship commonly result in enhancement of activation or functional connectivity of the reward system, including the striatum, the structure underlying romantic relationship-related regions remain unclear. Because individual experiences can alter gray matter within the adult human brain, we hypothesized that ro...

  6. From Standard Application Packages to Enterprise Systems - A Matter of Opportunities

    Science.gov (United States)

    Nilsson, Anders G.

    The purpose of this chapter is to make clearer the meaning behind the concepts of “standard application package” and “enterprise system.” There is today a confusion in our IS field about the connection between the two concepts and how they have appeared historically? The main idea is to contrast them against each other and in this sense to study which opportunities organizations and companies can achieve with these two different IT environments. This transparency will give business and IT people a better understanding for managing investments in information systems more professionally. The research approach is characterized as “consumable research” (Robey, and Markus, Information Resources Management Journal, 11(1): 7-15, 1998) based on theoretical knowledge integrated with business practice from the IS field. Our background is through working with practical methods for customer involvement (purchasing, implementation, maintenance) as well as performing vendor studies of the software application industry.

  7. Varieties of integrative scholarship: why rules of evidence, criteria, and standards matter.

    Science.gov (United States)

    McGaghie, William C

    2015-03-01

    Integrative scholarship involves the aggregation of data and evidence in a way that allows the research community to comprehend and value the connections and perspectives that unite isolated facts and research studies. Integrative scholarship summarizes data, enlightens and informs readers broadly, and sets the stage for subsequent research. This article describes five approaches to integrative scholarship--narrative, systematic, scoping, critical-realist, open peer commentary--and argues that each approach uses different methods and rules of evidence to combine data and report their meaning. Different forms of integrative scholarship use methods, criteria, and standards that are matched to the integrative approach and data being evaluated. There is no one best strategy to conduct or judge integrative scholarship. Researchers who perform integrative scholarship should openly express the values that underlie their work.

  8. Curriculum guidelines, standards and skills in spanish language. from untamed industrial objectivity to student’s harmless subjectivity

    Directory of Open Access Journals (Sweden)

    Franklin Yessid Arias Bedoya

    2015-07-01

    Full Text Available Competency Based Education is a curricular approach that, in addition to the controversy it arises, establishes practices and specific thoughts in schools: its origin from behavioral theories and their connection to the economic field disclose formation objectives that highlight the need of thinking about teaching practices and institutional curricula. These goals linked to projects such as work-oriented education and the propaedeutic cycles reveal the implicit intentions in the education system, where students’ specific characteristics yield to national economic imperatives. This reflection paper seeks to explore and define the ‘conceptual gap’ between an education based on the ideals of trade logic, and one directed to the aesthetic and socio-political formation of the subject, on the basis of legal documents as the Curricular Guidelines, Skill Standards for Spanish Language, Law 39 of 1903, General Law of Education and texts by various educational theorists such as Paulo Freire and Gimeno Sacristan.

  9. Standardization of reflectance measurements in dispersed organic matter: results of an exercise to improve interlaboratory agreement

    Science.gov (United States)

    Hackley, Paul C.; Araujo, Carla Viviane; Borrego, Angeles G.; Bouzinos, Antonis; Cardott, Brian; Cook, Alan C.; Eble, Cortland; Flores, Deolinda; Gentzis, Thomas; Gonçalves, Paula Alexandra; Filho, João Graciano Mendonça; Hámor-Vidó, Mária; Jelonek, Iwona; Kommeren, Kees; Knowles, Wayne; Kus, Jolanta; Mastalerz, Maria; Menezes, Taíssa Rêgo; Newman, Jane; Pawlewicz, Mark; Pickel, Walter; Potter, Judith; Ranasinghe, Paddy; Read, Harold; Reyes, Julito; Rodriguez, Genaro De La Rosa; de Souza, Igor Viegas Alves Fernandes; Suarez-Ruiz, Isabel; Sýkorová, Ivana; Valentine, Brett J.

    2015-01-01

    Vitrinite reflectance generally is considered the most robust thermal maturity parameter available for application to hydrocarbon exploration and petroleum system evaluation. However, until 2011 there was no standardized methodology available to provide guidelines for vitrinite reflectance measurements in shale. Efforts to correct this deficiency resulted in publication of ASTM D7708: Standard test method for microscopical determination of the reflectance of vitrinite dispersed in sedimentary rocks. In 2012-2013, an interlaboratory exercise was conducted to establish precision limits for the D7708 measurement technique. Six samples, representing a wide variety of shale, were tested in duplicate by 28 analysts in 22 laboratories from 14 countries. Samples ranged from immature to overmature (0.31-1.53% Ro), from organic-lean to organic-rich (1-22 wt.% total organic carbon), and contained Type I (lacustrine), Type II (marine), and Type III (terrestrial) kerogens. Repeatability limits (maximum difference between valid repetitive results from same operator, same conditions) ranged from 0.03-0.11% absolute reflectance, whereas reproducibility limits (maximum difference between valid results obtained on same test material by different operators, different laboratories) ranged from 0.12-0.54% absolute reflectance. Repeatability and reproducibility limits degraded consistently with increasing maturity and decreasing organic content. However, samples with terrestrial kerogens (Type III) fell off this trend, showing improved levels of reproducibility due to higher vitrinite content and improved ease of identification. Operators did not consistently meet the reporting requirements of the test method, indicating that a common reporting template is required to improve data quality. The most difficult problem encountered was the petrographic distinction of solid bitumens and low-reflecting inert macerals from vitrinite when vitrinite occurred with reflectance ranges overlapping

  10. Effect of dimethyl fumarate on gray and white matter pathology in subjects with relapsing multiple sclerosis: a longitudinal study.

    Science.gov (United States)

    Zivadinov, R; Hagemeier, J; Bergsland, N; Tavazzi, E; Weinstock-Guttman, B

    2018-03-01

    Dimethyl fumarate (DMF) is an oral treatment for relapsing-remitting multiple sclerosis (MS) with anti-inflammatory and possible neuroprotective properties. Its effect on white matter and gray matter pathology is still not fully understood. The aim of the study was to characterize the effect of DMF on normal-appearing white matter (NAWM) and thalamic pathology longitudinally. In this observational, longitudinal, 24-month magnetic resonance imaging study, 75 patients with relapsing-remitting MS treated with DMF and 40 age- and sex-matched healthy individuals were enrolled. Regional diffusion tensor imaging metrics and tract-based spatial statistics analyses were used to assess differences between groups. Mean diffusivity, axial diffusivity, radial diffusivity and fractional anisotropy were measured in the thalamus and NAWM. Baseline differences and changes over time were evaluated within and between study groups. At baseline, patients with MS showed significantly increased diffusivity and decreased fractional anisotropy in the thalamus (P < 0.001 for mean diffusivity, axial diffusivity and radial diffusivity) and NAWM (all P < 0.016) compared with healthy individuals. No significant within-group difference was found in diffusion tensor imaging measures over 24 months in either group. Healthy individuals showed a significantly greater rate of increased diffusivity parameters in the thalamus and NAWM compared with patients with MS, over 24 months (P < 0.05). The lack of changes in diffusion tensor imaging metrics in patients with MS over 24 months possibly indicates a neuroprotective role of DMF. These findings provide additional evidence of the beneficial effect of DMF on MS-related pathology. © 2018 EAN.

  11. Effective Field Theory of Majorana Dark Matter

    OpenAIRE

    Han, Huayong; WU, HONGYAN; Zheng, Sibo

    2017-01-01

    Thermal Majorana dark matter is explored from the viewpoint of effective field theory. Completely analytic result for dark matter annihilation into standard model background is derived in order to account relic density. The parameter space subject to the latest LUX, PandaX-II and Xenon-1T limits is shown in a model-independent way. For illustration, applications to singlet-doublet and neutralino dark matter are work out.

  12. Corpus callosum atrophy is associated with mental slowing and executive deficits in subjects with age-related white matter hyperintensities: the LADIS Study

    DEFF Research Database (Denmark)

    Jokinen, Hanna; Ryberg, Charlotte; Kalska, Hely

    2007-01-01

    , attention and executive functions in subjects with age-related white matter hyperintensities (WMH). METHODS: In the Leukoaraiosis and Disability Study, 567 subjects with age-related WMH were examined with a detailed neuropsychological assessment and quantitative magnetic resonance imaging. The relationships...... processing--namely, trail making A and Stroop test parts I and II. Anterior, but not posterior, corpus callosum atrophy was associated with deficits of attention and executive functions as reflected by the symbol digit modalities and digit cancellation tests, as well as by the subtraction scores in the trail...... is related to the frontal-lobe-mediated executive functions and attention, whereas overall corpus callosum atrophy is associated with the slowing of processing speed. Udgivelsesdato: 2007-May...

  13. It matters how old you feel: Antecedents and performance consequences of average relative subjective age in organizations.

    Science.gov (United States)

    Kunze, Florian; Raes, Anneloes M L; Bruch, Heike

    2015-09-01

    This article extends the conceptual knowledge of average relative subjective age in organizations by exploring organizational-level antecedents and consequences of employees, on average, feeling younger than their chronological age. We draw from the theories of selection-optimization-compensation and socioemotional selectivity to build a theoretical framework for relative subjective age in organizations. We hypothesize that companies in which employees, on average, perceive themselves to be younger than they actually are have a higher average individual goal accomplishment and, in turn, experience higher company performance. We further hypothesize that employees' average experience of high work-related meaning relates to a lower subjective age in organizations. In addition, we assess the role of environmental dynamism and age-inclusive human resource management as moderators in this theoretical model. Through empirically testing this model in a multisource dataset, including 107 companies with 15,164 participating employees, we received support for the hypothesized relationships. Our results contribute to current debates in the scientific literature on age and have important practical implications in light of the demographic changes faced by many companies. This research indicates to both researchers and practitioners that it is not employees' chronological age but their subjective age, a factor that can be influenced, which drives organizational performance outcomes. (c) 2015 APA, all rights reserved).

  14. Subjective Reactions to Non-standard Pronunciations in Great Russian and American English: A Comparison of Two Matched-Guise Studies.

    Science.gov (United States)

    Andrews, David R.

    1994-01-01

    Tests the subjective reactions of standard Russian speakers and American English speakers to regional pronunciation. Homogeneously-grouped subjects listened to a series of recorded voices and rated each speaker for various attributes on a numerical scale. These attributes included competence, personal integrity, and social attractiveness. (CK)

  15. Validation by numerical simulation of the behaviour of protective structures of machinery cabins subjected to standardized shocks

    Science.gov (United States)

    Dumitrache, P.; Goanţă, A. M.

    2017-08-01

    The ability of the cabins to insure the operator protection in the case of the shock loading that appears at the roll-over of the machine or when the cab is struck by the falling objects, it’s one of the most important performance criterions that it must comply by the machines and the mobile equipments. The experimental method provides the most accurate information on the behaviour of protective structures, but generates high costs due to experimental installations and structures which may be compromised during the experiments. In these circumstances, numerical simulation of the actual problem (mechanical shock applied to a strength structure) is a perfectly viable alternative, given that the hardware and software current performances provides the necessary support to obtain results with an acceptable level of accuracy. In this context, the paper proposes using FEA platforms for virtual testing of the actual strength structures of the cabins using their finite element models based on 3D models generated in CAD environments. In addition to the economic advantage above mentioned, although the results obtained by simulation using the finite element method are affected by a number of simplifying assumptions, the adequate modelling of the phenomenon can be a successful support in the design process of structures to meet safety performance criteria imposed by current standards. In the first section of the paper is presented the general context of the security performance requirements imposed by current standards on the cabins strength structures. The following section of the paper is dedicated to the peculiarities of finite element modelling in problems that impose simulation of the behaviour of structures subjected to shock loading. The final section of the paper is dedicated to a case study and to the future objectives.

  16. Single-subject gray matter graph properties and their relationship with cognitive impairment in early- and late-onset Alzheimer's disease.

    Science.gov (United States)

    Tijms, Betty M; Yeung, Hiu M; Sikkes, Sietske A M; Möller, Christiane; Smits, Lieke L; Stam, Cornelis J; Scheltens, Philip; van der Flier, Wiesje M; Barkhof, Frederik

    2014-06-01

    Abstract We investigated the relationships between gray matter graph properties and cognitive impairment in a sample of 215 patients with Alzheimer's disease (AD) and also whether age of disease onset modifies such relationships. We expected that more severe cognitive impairment in AD would be related to more random graph topologies. Single-subject gray matter graphs were constructed from T1-weighted magnetic resonance imaging scans. The following global and local graph properties were calculated: betweenness centrality, normalized clustering coefficient γ, and normalized path length λ. Local clustering, path length, and betweenness centrality measures were determined for 90 anatomically defined areas. Regression models with as interaction term age of onset (i.e., early onset when patients were ≤65 years old and late onset when they were >65 years old at the time of diagnosis)×graph property were used to assess the relationships between cognitive functioning in five domains (memory, language, visuospatial, attention, and executive). Worse cognitive impairment was associated with more random graphs, as indicated by low γ, λ, and betweenness centrality values. Three interaction effects for age of onset×global graph property were found: Low γ and λ values more strongly related to memory impairment in early-onset patients; low beta values were significantly related to impaired visuospatial functioning in late-onset patients. For the local graph properties, language impairment showed the strongest relationship with decreased clustering coefficient in the left superior temporal gyrus across the entire sample. Our study shows that single-subject gray matter graph properties are associated with individual differences in cognitive impairment.

  17. Computer-Based Instruction: Effect of Cognitive Style, Instructional Format, and Subject-Matter Content on Learning

    Science.gov (United States)

    1990-04-01

    for this study. The test consists of 10 pairs of words (see Appendix B), ranked from easy to hard, selected from the Weschler Paired Associate Learning...facts and opinions on a current affairs topic. The decision-making task involved a maze problem. Subjects were tested immediately after training, 2...Screening Measures for Cognitive Style ........................ 5 The 4-Mat Test ......................................... 5 The Lateral Preference Test

  18. Investigation of Psychophysiological and Subjective Effects of Long Working Hours – Do Age and Hearing Impairment Matter?

    Directory of Open Access Journals (Sweden)

    Verena Wagner-Hartl

    2018-01-01

    Full Text Available Following current prognosis, demographic development raises expectations of an aging of the working population. Therefore, keeping employees healthy and strengthening their ability to work, becomes more and more important. When employees become older, dealing with age-related impairments of sensory functions, such as hearing impairment, is a central issue. Recent evidence suggests that negative effects that are associated with reduced hearing can have a strong impact at work. Especially under exhausting working situations such as working overtime hours, age and hearing impairment might influence employees’ well-being. Until now, neither the problem of aged workers and long working hours, nor the problem of hearing impairment and prolonged working time has been addressed explicitly. Therefore, a laboratory study was examined to answer the research question: Do age and hearing impairment have an impact on psychophysiological and subjective effects of long working hours. In total, 51 white-collar workers, aged between 24 and 63 years, participated in the laboratory study. The results show no significant effects for age and hearing impairment on the intensity of subjective consequences (perceived recovery and fatigue, subjective emotional well-being and physical symptoms of long working hours. However, the psychophysiological response (the saliva cortisol level to long working hours differs significantly between hearing impaired and normal hearing employees. Interestingly, the results suggest that from a psychophysiological point of view long working hours were more demanding for normal hearing employees.

  19. Review of the Secondary National Ambient Air Quality Standard for Nitrogen Oxides, Sulfur Oxides and Particulate Matter: Risk and Exposure Assessment Planning Document

    Science.gov (United States)

    The U.S. Environmental Protection Agency (EPA) is conducting a review of the air quality criteria and the secondary (welfare-based) national ambient air quality standards (NAAQS) for nitrogen oxides (NOx), sulfur oxides (SOx), and particulate matter (PM). The major phases of the ...

  20. Directory of Book Trade and Related Organizations. Books Trade Associations, United States and Canada; International and Foreign Book Trade Associations; National Information Standards Organization (NISO) Standards; Calendar, 2003-2012; Acronyms; Index of Organizations; Subject Index.

    Science.gov (United States)

    Bowker Annual Library and Book Trade Almanac, 2003

    2003-01-01

    Includes two lists: one of book trade associations in the United States and Canada, and one of international and foreign book trade associations. Concludes with National Information Standards Organization (NISO) standards; calendar, 2003-2012; acronyms; index of organizations; and subject index. (LRW)

  1. Psychomotor performance in relation to acute oral administration of Delta9-tetrahydrocannabinol and standardized cannabis extract in healthy human subjects.

    Science.gov (United States)

    Roser, Patrik; Gallinat, Jürgen; Weinberg, Gordon; Juckel, Georg; Gorynia, Inge; Stadelmann, Andreas M

    2009-08-01

    Abnormalities in psychomotor performance are a consistent finding in schizophrenic patients as well as in chronic cannabis users. The high levels of central cannabinoid (CB(1)) receptors in the basal ganglia, the cerebral cortex and the cerebellum indicate their implication in the regulation of motor activity. Based on the close relationship between cannabis use, the endogenous cannabinoid system and motor disturbances found in schizophrenia, we expected that administration of cannabinoids may change pattern of psychomotor activity like in schizophrenic patients. This prospective, double-blind, placebo-controlled cross-over study investigated the acute effects of cannabinoids on psychomotor performance in 24 healthy right-handed volunteers (age 27.9 +/- 2.9 years, 12 male) by comparing Delta(9)-tetrahydrocannabinol (Delta(9)-THC) and standardized cannabis extract containing Delta(9)-THC and cannabidiol. Psychomotor performance was assessed by using a finger tapping test series. Cannabis extract, but not Delta(9)-THC, revealed a significant reduction of right-hand tapping frequencies that was also found in schizophrenia. As to the pure Delta(9)-THC condition, left-hand tapping frequencies were correlated with the plasma concentrations of the Delta(9)-THC metabolite 11-OH-THC. These effects are thought to be related to cannabinoid actions on CB(1) receptors in the basal ganglia, the cerebral cortex and the cerebellum. Our data further demonstrate that acute CB(1) receptor activation under the cannabis extract condition may also affect intermanual coordination (IMC) as an index of interhemispheric transfer. AIR-Scale scores as a measure of subjective perception of intoxication were dose-dependently related to IMC which was shown by an inverted U-curve. This result may be due to functional changes involving GABAergic and glutamatergic neurotransmission within the corpus callosum.

  2. Z'-portal right-handed neutrino dark matter in the minimal U(1 ) X extended Standard Model

    Science.gov (United States)

    Okada, Nobuchika; Okada, Satomi

    2017-02-01

    We consider a concise dark matter (DM) scenario in the context of a nonexotic U(1) extension of the Standard Model (SM), where a new U(1 ) X gauge symmetry is introduced along with three generations of right-handed neutrinos (RHNs) and a SM gauge singlet Higgs field. The model is a generalization of the minimal gauged U (1 )B -L (baryon number minus lepton number) extension of the SM, in which the extra U(1 ) X gauge symmetry is expressed as a linear combination of the SM U(1 ) Y and U (1 )B -L gauge symmetries. We introduce a Z2-parity and assign an odd-parity only for one RHN among all particles, so that this Z2-odd RHN plays the role of DM. The so-called minimal seesaw mechanism is implemented in this model with only two Z2-even RHNs. In this context, we investigate the physics of RHN DM, focusing on the case where this DM particle communicates with the SM particles through the U(1 ) X gauge boson (Z' boson). This "Z'-portal RHN DM" scenario is controlled by only three free parameters: the U(1 ) X gauge coupling (αX), the Z' boson mass (mZ'), and the U(1 ) X charge of the SM Higgs doublet (xH). We consider various phenomenological constraints to identify a phenomenologically viable parameter space. The most important constraints are the observed DM relic abundance and the latest LHC Run-2 results on the search for a narrow resonance with the dilepton final state. We find that these are complementary with each other and narrow the allowed parameter region, leading to the lower mass bound of mZ'≳2.7 TeV .

  3. Using National Ambient Air Quality Standards for fine particulate matter to assess regional wildland fire smoke and air quality management.

    Science.gov (United States)

    Schweizer, Don; Cisneros, Ricardo; Traina, Samuel; Ghezzehei, Teamrat A; Shaw, Glenn

    2017-10-01

    Wildland fire is an important ecological process in the California Sierra Nevada. Personal accounts from pre-20th century describe a much smokier environment than present day. The policy of suppression beginning in the early 20th century and climate change are contributing to increased megafires. We use a single particulate monitoring site at the wildland urban interface to explore impacts from prescribed, managed, and full suppression wildland fires from 2006 to 2015 producing a contextual assessment of smoke impacts over time at the landscape level. Prescribed fire had little effect on local fine particulate matter (PM2.5) air quality with readings typical of similar non-fire times; hourly and daily good to moderate Air Quality Index (AQI) for PM2.5, maximum hourly concentrations 21-103 μg m-3, and mean concentrations between 7.7 and 13.2 μg m-3. Hourly and daily AQI was typically good or moderate during managed fires with 3 h and one day reaching unhealthy while the site remained below National Ambient Air Quality Standards (NAAQS), with maximum hourly concentrations 27-244 μg m-3, and mean concentrations 6.7-11.7 μg m-3. The large high intensity fire in this area created the highest short term impacts (AQI unhealthy for 4 h and very unhealthy for 1 h), 11 unhealthy for sensitive days, and produced the only annual value (43.9 μg m-3) over the NAAQS 98th percentile for PM2.5 (35 μg m-3). Pinehurst remained below the federal standards for PM2.5 when wildland fire in the local area was managed to 7800 ha (8-22% of the historic burn area). Considering air quality impacts from smoke using the NAAQS at a landscape level over time can give land and air managers a metric for broader evaluation of smoke impacts particularly when assessing ecologically beneficial fire. Allowing managers to control the amount and timing of individual wildland fire emissions can help lessen large smoke impacts to public health from a megafire. Published by Elsevier Ltd.

  4. Predictive Utility of Marketed Volumetric Software Tools in Subjects at Risk for Alzheimer Disease: Do Regions Outside the Hippocampus Matter?

    Science.gov (United States)

    Tanpitukpongse, T P; Mazurowski, M A; Ikhena, J; Petrella, J R

    2017-03-01

    Alzheimer disease is a prevalent neurodegenerative disease. Computer assessment of brain atrophy patterns can help predict conversion to Alzheimer disease. Our aim was to assess the prognostic efficacy of individual-versus-combined regional volumetrics in 2 commercially available brain volumetric software packages for predicting conversion of patients with mild cognitive impairment to Alzheimer disease. Data were obtained through the Alzheimer's Disease Neuroimaging Initiative. One hundred ninety-two subjects (mean age, 74.8 years; 39% female) diagnosed with mild cognitive impairment at baseline were studied. All had T1-weighted MR imaging sequences at baseline and 3-year clinical follow-up. Analysis was performed with NeuroQuant and Neuroreader. Receiver operating characteristic curves assessing the prognostic efficacy of each software package were generated by using a univariable approach using individual regional brain volumes and 2 multivariable approaches (multiple regression and random forest), combining multiple volumes. On univariable analysis of 11 NeuroQuant and 11 Neuroreader regional volumes, hippocampal volume had the highest area under the curve for both software packages (0.69, NeuroQuant; 0.68, Neuroreader) and was not significantly different ( P > .05) between packages. Multivariable analysis did not increase the area under the curve for either package (0.63, logistic regression; 0.60, random forest NeuroQuant; 0.65, logistic regression; 0.62, random forest Neuroreader). Of the multiple regional volume measures available in FDA-cleared brain volumetric software packages, hippocampal volume remains the best single predictor of conversion of mild cognitive impairment to Alzheimer disease at 3-year follow-up. Combining volumetrics did not add additional prognostic efficacy. Therefore, future prognostic studies in mild cognitive impairment, combining such tools with demographic and other biomarker measures, are justified in using hippocampal volume as

  5. Standardization of definitions, notions of educational activity and relations between the object and the subject educational services according to the international standards

    Directory of Open Access Journals (Sweden)

    Олена Василівна Матвійчук-Юдіна

    2015-06-01

    Full Text Available This article involves basic problems of interpretation invariance of concepts regarding improving the quality of education in institutions of higher education in Ukraine. It gives an example of essential determinations, according to the international standards ISO 9001-10. It shows and describes the correlation between optimization of regulatory policy and international standards in order to improve the strategy of higher education development in Ukraine

  6. Reliability of the standard goniometry and diagrammatic recording of finger joint angles: a comparative study with healthy subjects and non-professional raters

    OpenAIRE

    Mačionis, Valdas

    2013-01-01

    Abstract Background Diagrammatic recording of finger joint angles by using two criss-crossed paper strips can be a quick substitute to the standard goniometry. As a preliminary step toward clinical validation of the diagrammatic technique, the current study employed healthy subjects and non-professional raters to explore whether reliability estimates of the diagrammatic goniometry are comparable with those of the standard procedure. Methods The study included two procedurally different parts,...

  7. Crucial requirement for standardization during the development of novel recombinant BCG vaccines: Does the corresponding substrain background matter?

    Science.gov (United States)

    Antas, P R Z

    2016-12-01

    The Bacillus Calmette-Guerin (BCG) vaccine is not a single organism, but consists of substrains that vary in genotypes and phenotypes. Actually, BCG is the common name given to a family of vaccines created in 1921 by the in vitro attenuation of a virulent Mycobacterium bovis in France. Even nearly a century of use, the BCG vaccine lingers generating confusion and debate due to its diversity and failure to protect against tuberculosis (TB). That is probably owing to the enduring lack of standardization during production, distribution and administration procedures. Since the 1940s, substantial sequence modifications among the BCG substrains have been described. To increase the level of complexity, even though that the prolific generation of recombinant BCG vaccines has been promising, the relationships between those candidates used in current clinical trials and their parental substrains are either unsatisfactorily connected or have been never fully delineated. Consequently, the use of the most protective BCG substrain as the background or platform in the development of all recombinant BCG vaccine candidates has not been standardized. In order to schematize and to clarify the subject regarding substrains commonly used to generate those novel vaccines, a sequential emergence of the parental BCG vaccine substrains and their matching recombinant ones, if any, was built. Hence, for a total of 24 BCG substrains currently in circulation worldwide, 9 have been used to sustain one or more genetic modifications, resulting in around 21 novel recombinant BCG vaccines. Although this is a remarkable success, only 2 out of the 21 recombinant BCG substrains harbor a background representative of the most immunogenic group. Systematizing the novel BCG vaccines and their parental strains may facilitate our understanding of protection provided by BCG immunizations.

  8. Standardized laryngeal videostroboscopic rating : Differences between untrained and trained male and female subjects, and effects of varying sound intensity, fundamental frequency, and age

    NARCIS (Netherlands)

    Sulter, AM; Schutte, HK; Miller, DG

    To determine the influence of the factors gender, vocal training, sound intensity, pitch, and aging on vocal function, videolaryngostroboscopic images of 214 subjects, subdivided according to gender and status of vocal training, were evaluated by three judges with standardized rating scales,

  9. When a gold standard isn't so golden: Lack of prediction of subjective sleep quality from sleep polysomnography.

    Science.gov (United States)

    Kaplan, Katherine A; Hirshman, Jason; Hernandez, Beatriz; Stefanick, Marcia L; Hoffman, Andrew R; Redline, Susan; Ancoli-Israel, Sonia; Stone, Katie; Friedman, Leah; Zeitzer, Jamie M

    2017-02-01

    Reports of subjective sleep quality are frequently collected in research and clinical practice. It is unclear, however, how well polysomnographic measures of sleep correlate with subjective reports of prior-night sleep quality in elderly men and women. Furthermore, the relative importance of various polysomnographic, demographic and clinical characteristics in predicting subjective sleep quality is not known. We sought to determine the correlates of subjective sleep quality in older adults using more recently developed machine learning algorithms that are suitable for selecting and ranking important variables. Community-dwelling older men (n=1024) and women (n=459), a subset of those participating in the Osteoporotic Fractures in Men study and the Study of Osteoporotic Fractures study, respectively, completed a single night of at-home polysomnographic recording of sleep followed by a set of morning questions concerning the prior night's sleep quality. Questionnaires concerning demographics and psychological characteristics were also collected prior to the overnight recording and entered into multivariable models. Two machine learning algorithms, lasso penalized regression and random forests, determined variable selection and the ordering of variable importance separately for men and women. Thirty-eight sleep, demographic and clinical correlates of sleep quality were considered. Together, these multivariable models explained only 11-17% of the variance in predicting subjective sleep quality. Objective sleep efficiency emerged as the strongest correlate of subjective sleep quality across all models, and across both sexes. Greater total sleep time and sleep stage transitions were also significant objective correlates of subjective sleep quality. The amount of slow wave sleep obtained was not determined to be important. Overall, the commonly obtained measures of polysomnographically-defined sleep contributed little to subjective ratings of prior-night sleep quality

  10. Dark matter in galaxies

    OpenAIRE

    Zasov, A. V.; Saburova, A. S.; Khoperskov, A. V.; Khoperskov, S. A.

    2017-01-01

    Dark matter in galaxies, its abundance, and its distribution remain a subject of long-standing discussion, especially in view of the fact that neither dark matter particles nor dark matter bodies have yet been found. Experts' opinions range from a very large number of completely dark galaxies exist to nonbaryonic dark matter does not exist at all in any significant amounts. We discuss astronomical evidence for the existence of dark matter and its connection with visible matter and examine att...

  11. Is Large-Scale-Structure formation a new probe of the Dark Matter interactions with Standard Model particles?

    CERN Multimedia

    CERN. Geneva

    2014-01-01

    In the last few decades, there have been extensive efforts made to discover dark matter particles through a significant experimental program based on direct and indirect detection techniques. However so far these searches remain unsuccessful, thus questioning our ability to elucidate one of the biggest challenges of modern Cosmology. In this talk I will review some of the key aspects of these techniques and present a new strategy to characterise the dark matter interactions with the visible sector without having to rely on critical assumptions.

  12. From the ideal market to the ideal clinic: constructing a normative standard of fairness for human subjects research.

    Science.gov (United States)

    Phillips, Trisha

    2011-02-01

    Preventing exploitation in human subjects research requires a benchmark of fairness against which to judge the distribution of the benefits and burdens of a trial. This paper proposes the ideal market and its fair market price as a criterion of fairness. The ideal market approach is not new to discussions about exploitation, so this paper reviews Wertheimer's inchoate presentation of the ideal market as a principle of fairness, attempt of Emanuel and colleagues to apply the ideal market to human subjects research, and Ballantyne's criticisms of both the ideal market and the resulting benchmark of fairness. It argues that the criticism of this particular benchmark is on point, but the rejection of the ideal market is mistaken. After presenting a complete account of the ideal market, this paper proposes a new method for applying the ideal market to human subjects research and illustrates the proposal by considering a sample case.

  13. A standardized method for the determination of the intrinsic carbon and nitrogen mineralization capacity of natural organic matter sources

    NARCIS (Netherlands)

    Grigatti, M.; Perez, M.D.; Blok, W.J.; Ciavatta, C.; Veeken, A.

    2007-01-01

    A new method was developed for the simultaneous determination of the intrinsic carbon and nitrogen mineralization capacity of organic matter (OM) sources by means of an aerobic incubation in suspension. The proposed method is based on determination of the oxygen consumption, monitored indirectly via

  14. THE NATURE OF DAMPED Ly{alpha} SYSTEMS AND THEIR HOSTS IN THE STANDARD COLD DARK MATTER UNIVERSE

    Energy Technology Data Exchange (ETDEWEB)

    Cen Renyue, E-mail: cen@astro.princeton.edu [Department of Astrophysical Sciences, Princeton University Observatory, Princeton, NJ 08544 (United States)

    2012-04-01

    Using adaptive mesh refinement cosmological hydrodynamic simulations with a physically motivated supernova feedback prescription, we show that the standard cold dark matter model can account for extant observed properties of damped Ly{alpha} systems (DLAs). With detailed examination of DLAs identified for each redshift snapshot through ray tracing through the simulation volumes containing thousands of galaxies, we find the following: (1) While DLA hosts roughly trace the overall population of galaxies at all redshifts, they are always gas-rich and have tendencies of being slightly smaller and bluer. (2) The history of DLA evolution is cosmological in nature and reflects primarily the evolution of the underlying cosmic density, galaxy size, and galaxy interactions. With higher density and more interactions at high redshift the size of DLAs is a larger fraction of their virial radius. (3) The variety of DLAs at high redshift is richer with a large contribution coming from galactic aqueducts, created through close galaxy interactions. The portion of gaseous disks of galaxies where most stars reside makes a relatively small contribution to DLA incidence at z = 3-4. (4) The majority of DLAs arise in halos of mass M{sub h} = 10{sup 10}-10{sup 12} M{sub Sun} at z = 1.6-4, as these galaxies dominate the overall population of galaxies then. At z = 3-4, 20%-30% of DLA hosts are Lyman break galaxies (LBGs), 10%-20% are due to galaxies more massive than LBGs, and 50%-70% are from smaller galaxies. (5) Galactic winds play an indispensable role in shaping the kinematic properties of DLAs. Specifically, the high velocity width DLAs are a mixture of those arising in high-mass, high velocity dispersion halos and those arising in smaller mass systems where cold gas clouds are entrained to high velocities by galactic winds. (6) In agreement with observations, we see a weak but noticeable evolution in DLA metallicity. The metallicity distribution centers at [Z/H] = -1.5 to -1 and

  15. Train, teach; taught? How the content of specific science subject matter knowledge sessions impacts on trainee teachers’ classroom practice and children’s learning

    Directory of Open Access Journals (Sweden)

    Vanessa Kind

    2008-11-01

    Full Text Available The impact science sessions for trainee science teachers have on 11-14 year olds’ learning of science was assessed using questionnaires and a “Video-Interview (trainee –Interview (pupils” (V-I-I technique devised for this study. V-I-I involved: video-recording trainee-taught lessons; and two interviews – with a pupil group to probe learning occurring in the lesson and with the trainee.Eighty UK-based trainees taking a one-year postgraduate teacher education course completed the questionnaire probing perceptions about university- and school-based training sessions designed to develop science subject matter knowledge (SMK and pedagogical content knowledge (PCK. Six trainees participated in V-I-I.Most trainees saw all sessions as SMK-based, regardless of teacher educators’ intended purposes. Lesson videos revealed ”describing” activities, task completion and good behaviour as main focii. Explanation of key science ideas and use of materials and /ideas from training sessions were largely absent. Trainee interviews revealed contrasts: most perceived a lesson as “successful” when children completed tasks quietly. Other trainees realised their understanding impacted on pupils’ learning science concepts. Pupil interviews showed positive attitudes towards science and learning difficult ideas, but little specific learning of topics taught.

  16. A tale of three blind men on the proper subject matter of clinical science and practice: commentary on Plaud's behaviorism vs. Ilardi and Feldman's cognitive neuroscience.

    Science.gov (United States)

    Forsyth, J P; Kelly, M M

    2001-09-01

    Plaud (J Clin Psychol 57, 1089-1102, 1109-1111, 1119-1120) and Ilardi and Feldman (J Clin Psychol 57, 1067-1088, 1103-1107, 1113-1117, 1121-1124) argue for two very different approaches to clinical science and practice (i.e., behavior analysis and cognitive neuroscience, respectively). We comment on the assets and liabilities of both perspectives as presented and attempt to achieve some semblance of balance between the three protagonists embroiled in this current debate. The vision of clinical science we articulate is more ecumenical and evolutionary, rather than paradigmatic and revolutionary. As we see it, the problem clinical psychology faces is much larger than the authors let on; namely, how best to make clinical science meaningful and relevant to practitioners, consumers, the general public, and the behavioral health-care community. Clinical psychology's immediate internal problem is not pluralism with regard to subject matter, worldview, methodology, or school of thought, but pluralism in clinical psychologists' adherence to a scientific epistemology as the only legitimate form of clinical psychology. On this latter point, we still have a very long way to go. Copyright 2001 John Wiley & Sons, Inc.

  17. Reliability of the standard goniometry and diagrammatic recording of finger joint angles: a comparative study with healthy subjects and non-professional raters.

    Science.gov (United States)

    Macionis, Valdas

    2013-01-09

    Diagrammatic recording of finger joint angles by using two criss-crossed paper strips can be a quick substitute to the standard goniometry. As a preliminary step toward clinical validation of the diagrammatic technique, the current study employed healthy subjects and non-professional raters to explore whether reliability estimates of the diagrammatic goniometry are comparable with those of the standard procedure. The study included two procedurally different parts, which were replicated by assigning 24 medical students to act interchangeably as 12 subjects and 12 raters. A larger component of the study was designed to compare goniometers side-by-side in measurement of finger joint angles varying from subject to subject. In the rest of the study, the instruments were compared by parallel evaluations of joint angles similar for all subjects in a situation of simulated change of joint range of motion over time. The subjects used special guides to position the joints of their left ring finger at varying angles of flexion and extension. The obtained diagrams of joint angles were converted to numerical values by computerized measurements. The statistical approaches included calculation of appropriate intraclass correlation coefficients, standard errors of measurements, proportions of measurement differences of 5 or less degrees, and significant differences between paired observations. Reliability estimates were similar for both goniometers. Intra-rater and inter-rater intraclass correlation coefficients ranged from 0.69 to 0.93. The corresponding standard errors of measurements ranged from 2.4 to 4.9 degrees. Repeated measurements of a considerable number of raters fell within clinically non-meaningful 5 degrees of each other in proportions comparable with a criterion value of 0.95. Data collected with both instruments could be similarly interpreted in a simulated situation of change of joint range of motion over time. The paper goniometer and the standard goniometer can

  18. Reliability of the standard goniometry and diagrammatic recording of finger joint angles: a comparative study with healthy subjects and non-professional raters

    Directory of Open Access Journals (Sweden)

    Macionis Valdas

    2013-01-01

    Full Text Available Abstract Background Diagrammatic recording of finger joint angles by using two criss-crossed paper strips can be a quick substitute to the standard goniometry. As a preliminary step toward clinical validation of the diagrammatic technique, the current study employed healthy subjects and non-professional raters to explore whether reliability estimates of the diagrammatic goniometry are comparable with those of the standard procedure. Methods The study included two procedurally different parts, which were replicated by assigning 24 medical students to act interchangeably as 12 subjects and 12 raters. A larger component of the study was designed to compare goniometers side-by-side in measurement of finger joint angles varying from subject to subject. In the rest of the study, the instruments were compared by parallel evaluations of joint angles similar for all subjects in a situation of simulated change of joint range of motion over time. The subjects used special guides to position the joints of their left ring finger at varying angles of flexion and extension. The obtained diagrams of joint angles were converted to numerical values by computerized measurements. The statistical approaches included calculation of appropriate intraclass correlation coefficients, standard errors of measurements, proportions of measurement differences of 5 or less degrees, and significant differences between paired observations. Results Reliability estimates were similar for both goniometers. Intra-rater and inter-rater intraclass correlation coefficients ranged from 0.69 to 0.93. The corresponding standard errors of measurements ranged from 2.4 to 4.9 degrees. Repeated measurements of a considerable number of raters fell within clinically non-meaningful 5 degrees of each other in proportions comparable with a criterion value of 0.95. Data collected with both instruments could be similarly interpreted in a simulated situation of change of joint range of motion over

  19. Low-dose ticagrelor yields an antiplatelet efficacy similar to that of standard-dose ticagrelor in healthy subjects: an open-label randomized controlled trial

    OpenAIRE

    Pan Li; Ying Gu; Yawei Yang; Lizhi Chen; Junmei Liu; Lihong Gao; Yongwen Qin; Quancai Cai; Xianxian Zhao; Zhuo Wang; Liping Ma

    2016-01-01

    Ticagrelor has a greater antiplatelet efficacy than clopidogrel but may be accompanied by an increased risk of bleeding. This study evaluated the antiplatelet effect and pharmacokinetic profile of low-dose ticagrelor in healthy Chinese volunteers. Thirty healthy subjects were randomized to receive standard-dose ticagrelor (180-mg loading dose, 90-mg twice daily [bid] [n?=?10]), low-dose ticagrelor (90-mg loading dose, 45-mg bid [n?=?10]), or clopidogrel (600-mg loading dose, 75-mg once daily ...

  20. The disintegration behaviour of capsules in fed subjects: a comparison of hypromellose (carrageenan) capsules and standard gelatin capsules.

    Science.gov (United States)

    Jones, B E; Basit, A W; Tuleu, C

    2012-03-15

    Two-piece hard shell capsules made from hypromellose (or hydroxypropyl methylcellulose, HPMC) containing carrageenan as a gelling agent have been proposed as an alternative to conventional gelatin capsules for oral drug delivery. We have previously compared the disintegration of hypromellose(carrageenan) (Quali-V(®)) and gelatin capsules (Qualicaps) in fasted human subjects using the technique of gamma scintigraphy. This second study used the same technique with both fasted and fed human subjects. Size 0 capsules were filled with powder plugs made from lactose and did not contain croscarmellose as in the original study. The capsules were separately radiolabelled with indium-111 and technetium-99m. Both capsules were administered simultaneously with 180ml water to eight healthy male subjects following an overnight fast. Each volunteer was positioned in front of the gamma camera and sequential 60s images were acquired in a continuous manner for 30min. The mean (±S.D.) disintegration time in the fasted state for the hypromellose(carrageenan) capsules was 8±2min and for gelatin 7±3min. These results were not statistically different from the data in the original study and show that the removal of the croscarmellose had no effect on the results. The mean (±S.D.) disintegration time in the fed state for the hypromellose(carrageenan) capsules was 16±5min and for the gelatin capsules was 12±4min. There was no statistical difference between the hypromellose(carrageenan) and gelatin capsules in either the fed or fasted state. Copyright © 2012 Elsevier B.V. All rights reserved.

  1. Tests and prospects of new physics at very high energy. Beyond the standard basic principles, and beyond conventional matter and space-time. On the possible origin of Quantum Mechanics.

    Directory of Open Access Journals (Sweden)

    Gonzalez-Mestres Luis

    2015-01-01

    crucial open subjects, together with vacuum structure and the interaction between vacuum and standard matter.

  2. Simulated Prism Therapy in Virtual Reality produces larger after-effects than standard prism exposure in normal healthy subject - Implications for Neglect Therapy

    DEFF Research Database (Denmark)

    Wilms, Inge Linda

    2018-01-01

    BACKGROUND: Virtual reality is an important area of exploration within computer-based cognitive rehabilitation of visual neglect. Virtual reality will allow for closer monitoring of patient behaviour during prism adaptation therapy and perhaps change the way we induce prismatic after......-effects. OBJECTIVE: This study compares the effect of two different prism simulation conditions in virtual reality to a standard exposure to prism goggles after one session of Prism Adaptation Therapy in healthy subjects. METHOD: 20 healthy subjects were subjected to one session of prism adaptation therapy under...... three prism conditions: 2 different types of simulated prism techniques in virtual reality and a control session using a set of prism goggles. RESULTS: The study shows that the simulated prism conditions in virtual reality with HTC Vive produced prismatic after-effects larger in size than the after...

  3. Ambient air concentrations exceeded health-based standards for fine particulate matter and benzene during the Deepwater Horizon oil spill.

    Science.gov (United States)

    Nance, Earthea; King, Denae; Wright, Beverly; Bullard, Robert D

    2016-02-01

    The Deepwater Horizon oil spill is considered one of the largest marine oil spills in the history of the United States. Air emissions associated with the oil spill caused concern among residents of Southeast Louisiana. The purpose of this study was to assess ambient concentrations of benzene (n=3,887) and fine particulate matter (n=102,682) during the oil spill and to evaluate potential exposure disparities in the region. Benzene and fine particulate matter (PM2.5) concentrations in the targeted parishes were generally higher following the oil spill, as expected. Benzene concentrations reached 2 to 19 times higher than background, and daily exceedances of PM2.5 were 10 to 45 times higher than background. Both benzene and PM2.5 concentrations were considered high enough to exceed public health criteria, with measurable exposure disparities in the coastal areas closer to the spill and clean-up activities. These findings raise questions about public disclosure of environmental health risks associated with the oil spill. The findings also provide a science-based rationale for establishing health-based action levels in future disasters. Benzene and particulate matter monitoring during the Deepwater Horizon oil spill revealed that ambient air quality was a likely threat to public health and that residents in coastal Louisiana experienced significantly greater exposures than urban residents. Threshold air pollution levels established for the oil spill apparently were not used as a basis for informing the public about these potential health impacts. Also, despite carrying out the most comprehensive air monitoring ever conducted in the region, none of the agencies involved provided integrated analysis of the data or conclusive statements about public health risk. Better information about real-time risk is needed in future environmental disasters.

  4. Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast

    DEFF Research Database (Denmark)

    Nilsson, Anne C; Ostman, Elin M; Holst, Jens Juul

    2008-01-01

    tolerance and related variables after a subsequent standardized breakfast in healthy subjects (n = 15). At breakfast, blood was sampled for 3 h for analysis of blood glucose, serum insulin, serum FFA, serum triacylglycerides, plasma glucagon, plasma gastric-inhibitory peptide, plasma glucagon-like peptide-1...... (GLP-1), serum interleukin (IL)-6, serum IL-8, and plasma adiponectin. Satiety was subjectively rated after breakfast and the gastric emptying rate (GER) was determined using paracetamol as a marker. Breath hydrogen was measured as an indicator of colonic fermentation. Evening meals with barley kernel......-kernel bread compared with WWB. Breath hydrogen correlated positively with satiety (r = 0.27; P metabolic risk variables at breakfast...

  5. The Role of Teachers' Pedagogical and Subject-Matter Knowledge in Planning and Enacting Science-Inquiry Instruction, and in Assessing Students' Science-Inquiry Learning

    Science.gov (United States)

    Birlean, Camelia

    This study explored the relation between pedagogical knowledge and subject-matter knowledge, in the context of inquiry-driven science instruction, and their relation to instructors' performance in the instructional process. This multiple case study focused on three distinct categories of teachers--Novice in Inquiry and in Science, Novice in Inquiry and Expert in Science, and Expert in Inquiry and in Science--and examined the commonalities and differences among them by exploring the cognitive processes these teachers used when planning and enacting an inquiry instructional situation, as well as when assessing students' learning resulting from this specific instructional event. Inquiry instruction varied across cases from largely structured to largely open. The Novice-Novice's science instruction, predominantly traditional in the approach, differed greatly from that of the Expert-Expert and of the Novice-Expert. The latter two emphasized--to various extents structured, guided, and open--inquiry strategy as part of their ongoing instruction. The open inquiry was an approach embraced solely by the Expert-Expert teacher throughout the Advanced Science Research instruction, emphasizing the creative aspect of problem generation. Edward teacher also distinguished himself from the other two participants in his view of planning and terminology used to describe it, both of which emphasized the dynamic and flexible feature of this instructional process. The Expert-Expert identified occasional planning, planning of specific skills and content critical to students' learning process during their independent inquiry. The observed teaching performance of the three participants partly reflected their planning; the alignment was least frequent for the Novice-Novice. The assessment of inquiry-based projects varied greatly across participants. Each teacher participant evaluated a set of three inquiry-based science projects that differed in their quality, and this variation increased

  6. Low-dose ticagrelor yields an antiplatelet efficacy similar to that of standard-dose ticagrelor in healthy subjects: an open-label randomized controlled trial.

    Science.gov (United States)

    Li, Pan; Gu, Ying; Yang, Yawei; Chen, Lizhi; Liu, Junmei; Gao, Lihong; Qin, Yongwen; Cai, Quancai; Zhao, Xianxian; Wang, Zhuo; Ma, Liping

    2016-08-24

    Ticagrelor has a greater antiplatelet efficacy than clopidogrel but may be accompanied by an increased risk of bleeding. This study evaluated the antiplatelet effect and pharmacokinetic profile of low-dose ticagrelor in healthy Chinese volunteers. Thirty healthy subjects were randomized to receive standard-dose ticagrelor (180-mg loading dose, 90-mg twice daily [bid] [n = 10]), low-dose ticagrelor (90-mg loading dose, 45-mg bid [n = 10]), or clopidogrel (600-mg loading dose, 75-mg once daily [n = 10]). Platelet reactivity was assessed by using the VerifyNow P2Y12 assay at baseline and 0.5, 1, 2, 4, 8, 24, 48, and 72 hours post-dosing. The ticagrelor and AR-C124910XX concentrations were measured for pharmacokinetic analysis. The percentage inhibition of P2Y12 reaction units was higher in the low-dose and standard-dose ticagrelor group than in the clopidogrel group at 0.5, 1, 2, 4, 8, and 48 hours post-dosing (P ticagrelor doses at any time-point (P > 0.05). The plasma ticagrelor and ARC124910XX concentrations were approximately 2-fold higher with standard-dose versus low-dose ticagrelor. No serious adverse events were reported. In conclusion, low-dose ticagrelor achieved faster and higher inhibition of platelet functions in healthy Chinese subjects than did clopidogrel, with an antiplatelet efficacy similar to that of standard-dose ticagrelor.

  7. Total sleep time in Muslim football players is reduced during Ramadan: a pilot study on the standardized assessment of subjective sleep-wake patterns in athletes.

    Science.gov (United States)

    Herrera, Christopher P

    2012-01-01

    Ramadan is a period in which Muslims fast during daylight hours and is associated with disturbances in sleep-wake behaviour and adverse effects on physical and mental health in normal volunteers. Studies using athletes are rare and remain equivocal as to whether Ramadan influences sleep-wake patterns. Notably, the standardized assessment of subjective sleep quality and daytime sleepiness in athletes has not been established. This study employed the Arabic version of the Pittsburgh Sleep Quality Index, Insomnia Severity Index, and Epworth Sleepiness Scale in nine football players aged 20-35 years (mean ± s: 26 ± 4) one week before and during the last week of Ramadan. Compliance rates with self-administration were high (71%) and the results demonstrated a robust decline in total sleep time (before Ramadan: 6.6 ± 2 h; at the end of Ramadan: 5.3 ± 1 h; P effect size 0.81). Compared with previous research, the study questionnaires offer improved methodology, including less time constraints plus standardization in scoring. Thus, this study demonstrates a framework for greater reproducibility and reliability in the assessment of subjective sleep-wake patterns in athletes before and during Ramadan.

  8. High Pressure Size Exclusion Chromatography (HPSEC) Determination of Dissolved Organic Matter Molecular Weight Revisited: Accounting for Changes in Stationary Phases, Analytical Standards, and Isolation Methods.

    Science.gov (United States)

    McAdams, Brandon C; Aiken, George R; McKnight, Diane M; Arnold, William A; Chin, Yu-Ping

    2018-01-16

    We reassessed the molecular weight of dissolved organic matter (DOM) determined by high pressure size exclusion chromatography (HPSEC) using measurements made with different columns and various generations of polystyrenesulfonate (PSS) molecular weight standards. Molecular weight measurements made with a newer generation HPSEC column and PSS standards from more recent lots are roughly 200 to 400 Da lower than initial measurements made in the early 1990s. These updated numbers match DOM molecular weights measured by colligative methods and fall within a range of values calculated from hydroxyl radical kinetics. These changes suggest improved accuracy of HPSEC molecular weight measurements that we attribute to improved accuracy of PSS standards and changes in the column packing. We also isolated DOM from wetlands in the Prairie Pothole Region (PPR) using XAD-8, a cation exchange resin, and PPL, a styrene-divinylbenzene media, and observed little difference in molecular weight and specific UV absorbance at 280 nm (SUVA 280 ) between the two solid phase extraction resins, suggesting they capture similar DOM moieties. PPR DOM also showed lower SUVA 280 at similar weights compared to DOM isolates from a global range of environments, which we attribute to oxidized sulfur in PPR DOM that would increase molecular weight without affecting SUVA 280 .

  9. Thermal desorption GC-MS as a tool to provide PAH certified standard reference material on particulate matter quartz filters.

    Science.gov (United States)

    Grandesso, Emanuela; Pérez Ballesta, Pascual; Kowalewski, Konrad

    2013-02-15

    Reference materials for particulate matter (PM) on filter media are not available for the quantification of polycyclic aromatic hydrocarbons (PAHs) in ambient air. This is due to the difficulty of obtaining reference material that has a homogeneous distribution on a filter surface that is large enough for characterization and distribution. High volume sample filters from different locations and seasons were considered to validate the feasibility of the use of quartz filters as reference material for PAH concentrations. A rapid thermal desorption (TD) technique coupled with gas chromatography/mass spectroscopy was applied to characterise the material for the content of fifteen different PAHs. TD technique allowed for rapid and accurate analysis of small sections of filter (5mm diameter), leaving enough material for the production of twenty sub-filter cuts (42 mm diameter) that could be used for distribution and control. Stability and homogeneity tests required for material certification were performed as indicated by the ISO guide 34:2009 and ISO 35:2006. The contribution of the heterogeneous distribution of PAHs on the filter surface resulted generally lower than 10% and higher for more volatile PAHs. One year of storage at -18°C indicated no significant variation in PAH concentrations. Nevertheless, a methodology for shipping and storing of the filter material at ambient temperature in especially designed plastic envelopes, was also shown to allow for stabile concentrations within twenty days. The method accuracy was confirmed by the analysis of NIST SRM 1649a (urban dust) and PAH concentrations were validated against the reference values obtained from an inter-laboratory exercise. In the case of benzo[a]pyrene for masses quantified between 100 pg and 10 ng the TD method provided expanded uncertainties of circa 10%, while the inter-laboratory reference value uncertainties ranged between 15 and 20%. The evaluation of these results supports the use of the presented

  10. Solid-state 13C nuclear magnetic resonance spectroscopic characterization of soil organic matter fractions in a forest ecosystem subjected to prescribed burning and thinning

    Science.gov (United States)

    Prescribed burning and thinning are gaining popularity as low-cost forest protection measures. Such field management practices could alter the chemical properties of soil organic matter (SOM), especially humic substances. In this work, we collected surface soil samples from the Bankhead National For...

  11. Gray and white matter changes in subjective cognitive impairment, amnestic mild cognitive impairment and Alzheimer's disease: a voxel-based analysis study.

    Directory of Open Access Journals (Sweden)

    Kuniaki Kiuchi

    Full Text Available Subjective cognitive impairment may be a very early at-risk period of the continuum of dementia. However, it is difficult to discriminate at-risk states from normal aging. Thus, detection of the early pathological changes in the subjective cognitive impairment period is needed. To elucidate these changes, we employed diffusion tensor imaging and volumetry analysis, and compared subjective cognitive impairment with normal, mild cognitive impairment and Alzheimer's disease. The subjects in this study were 39 Alzheimer's disease, 43 mild cognitive impairment, 28 subjective cognitive impairment and 41 normal controls. There were no statistically significant differences between the normal control and subjective cognitive impairment groups in all measures. Alzheimer's disease and mild cognitive impairment had the same extent of brain atrophy and diffusion changes. These results are consistent with the hypothetical model of the dynamic biomarkers of Alzheimer's disease.

  12. Low episodic memory performance in cognitively normal elderly subjects is associated with increased posterior cingulate gray matter N-acetylaspartate: a1H MRSI study at 7 Tesla.

    Science.gov (United States)

    Schreiner, Simon J; Kirchner, Thomas; Wyss, Michael; Van Bergen, Jiri M G; Quevenco, Frances C; Steininger, Stefanie C; Griffith, Erica Y; Meier, Irene; Michels, Lars; Gietl, Anton F; Leh, Sandra E; Brickman, Adam M; Hock, Christoph; Nitsch, Roger M; Pruessmann, Klaas P; Henning, Anke; Unschuld, Paul G

    2016-12-01

    Low episodic memory performance characterizes elderly subjects at increased risk for Alzheimer's disease (AD) and may reflect neuronal dysfunction within the posterior cingulate cortex and precuneus (PCP) region. To investigate a potential association between cerebral neurometabolism and low episodic memory in the absence of cognitive impairment, tissue-specific magnetic resonance spectroscopic imaging at ultrahigh field strength of 7 Tesla was used to investigate the PCP region in a healthy elderly study population (n = 30, age 70 ± 5.7 years, Mini-Mental State Examination 29.4 ± 4.1). The Verbal Learning and Memory Test (VLMT) was administered as part of a neuropsychological battery for assessment of episodic memory performance. Significant differences between PCP gray and white matter could be observed for glutamate-glutamine (p = 0.001), choline (p = 0.01), and myo-inositol (p = 0.02). Low Verbal Learning and Memory Test performance was associated with high N-acetylaspartate in PCP gray matter (p = 0.01) but not in PCP white matter. Our data suggest that subtle decreases in episodic memory performance in the elderly may be associated with increased levels of N-acetylaspartate as a reflection of increased mitochondrial energy capacity in PCP gray matter. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast.

    Science.gov (United States)

    Nilsson, Anne C; Ostman, Elin M; Holst, Jens J; Björck, Inger M E

    2008-04-01

    Low-glycemic index (GI) foods and foods rich in whole grain are associated with reduced risk of type 2 diabetes and cardiovascular disease. We studied the effect of cereal-based bread evening meals (50 g available starch), varying in GI and content of indigestible carbohydrates, on glucose tolerance and related variables after a subsequent standardized breakfast in healthy subjects (n = 15). At breakfast, blood was sampled for 3 h for analysis of blood glucose, serum insulin, serum FFA, serum triacylglycerides, plasma glucagon, plasma gastric-inhibitory peptide, plasma glucagon-like peptide-1 (GLP-1), serum interleukin (IL)-6, serum IL-8, and plasma adiponectin. Satiety was subjectively rated after breakfast and the gastric emptying rate (GER) was determined using paracetamol as a marker. Breath hydrogen was measured as an indicator of colonic fermentation. Evening meals with barley kernel based bread (ordinary, high-amylose- or beta-glucan-rich genotypes) or an evening meal with white wheat flour bread (WWB) enriched with a mixture of barley fiber and resistant starch improved glucose tolerance at the subsequent breakfast compared with unsupplemented WWB (P carbohydrates of the evening meal may affect glycemic excursions and related metabolic risk variables at breakfast through a mechanism involving colonic fermentation. The results provide evidence for a link between gut microbial metabolism and key factors associated with insulin resistance.

  14. New light on a dark subject: On the use of fluorescence data to deduce redox states of natural organic matter (NOM)

    Science.gov (United States)

    Macalady, Donald L.; Walton-Day, Katherine

    2009-01-01

    This paper reports the use of excitation-emission matrix fluorescence spectroscopy (EEMS), parallel factor statistical analysis (PARAFAC), and oxidation-reduction experiments to examine the effect of redox conditions on PARAFAC model results for aqueous samples rich in natural organic matter. Fifty-four aqueous samples from 11 different geographic locations and two plant extracts were analyzed untreated and after chemical treatments or irradiation were used in attempts to change the redox status of the natural organic matter. The EEMS spectra were generated and modeled using a PARAFAC package developed by Cory and McKnight (2005). The PARAFAC model output was examined for consistency with previously reported relations and with changes expected to occur upon experimental oxidation and reduction of aqueous samples. Results indicate the implied fraction of total sample fluorescence attributed to quinone-like moieties was consistent (0.64 to 0.78) and greater than that observed by Cory and McKnight (2005). The fraction of the quinone-like moieties that was reduced (the reducing index, RI) showed relatively little variation (0.46 to 0.71) despite attempts to alter the redox status of the natural organic matter. The RI changed little after reducing samples using zinc metal, oxidizing at high pH with air, or irradiating with a Xenon lamp. Our results, however, are consistent with the correlations between the fluorescence indices (FI) of samples and the ratio of PARAFAC fitting parameters suggested by Cory and McKnight (2005), though we used samples with a much narrower range of FI values.

  15. Improved efficiency of extraction of polycyclic aromatic hydrocarbons (PAHs) from the National Institute of Standards and Technology (NIST) Standard Reference Material Diesel Particulate Matter (SRM 2975) using accelerated solvent extraction.

    Science.gov (United States)

    Masala, Silvia; Ahmed, Trifa; Bergvall, Christoffer; Westerholm, Roger

    2011-12-01

    The efficiency of extraction of polycyclic aromatic hydrocarbons (PAHs) with molecular masses of 252, 276, 278, 300, and 302 Da from standard reference material diesel particulate matter (SRM 2975) has been investigated using accelerated solvent extraction (ASE) with dichloromethane, toluene, methanol, and mixtures of toluene and methanol. Extraction of SRM 2975 using toluene/methanol (9:1, v/v) at maximum instrumental settings (200 °C, 20.7 MPa, and five extraction cycles) with 30-min extraction times resulted in the following elevations of the measured concentration when compared with the certified and reference concentrations reported by the National Institute of Standards and Technology (NIST): benzo[b]fluoranthene, 46%; benzo[k]fluoranthene, 137%; benzo[e]pyrene, 103%; benzo[a]pyrene, 1,570%; perylene, 37%; indeno[1,2,3-cd]pyrene, 41%; benzo[ghi]perylene, 163%; and coronene, 361%. The concentrations of the following PAHs were comparable to the reference values assigned by NIST: indeno[1,2,3-cd]fluoranthene, dibenz[a,h]anthracene, and picene. The measured concentration of dibenzo[a,e]-pyrene was lower than the information value reported by the NIST. The measured concentrations of other highly carcinogenic PAHs (dibenzo[a,l]pyrene, dibenzo[a,i]pyrene, and dibenzo[a,h]pyrene) in SRM 2975 are also reported. Comparison of measurements using the optimized ASE method and using similar conditions to those applied by the NIST for the assignment of PAH concentrations in SRM 2975 indicated that the higher values obtained in the present study were associated with more complete extraction of PAHs from the diesel particulate material. Re-extraction of the particulate samples demonstrated that the deuterated internal standards were more readily recovered than the native PAHs, which may explain the lower values reported by the NIST. The analytical results obtained in the study demonstrated that the efficient extraction of PAHs from SRM 2975 is a critical requirement for the

  16. Age, Cumulative Trauma and Stressful Life Events, and Post-Traumatic Stress Symptoms among Older Adults in Prison: Do Subjective Impressions Matter?

    Science.gov (United States)

    Maschi, Tina; Morgen, Keith; Zgoba, Kristen; Courtney, Deborah; Ristow, Jennifer

    2011-01-01

    Background: The aging prison population in the United States presents a significant public health challenge with high rates of trauma and mental health issues that the correctional system alone is ill-prepared to address. The purpose of this study was to examine the relationship of age, objective, and subjective measures of trauma and stressful…

  17. Using Academic Journals to Help Students Learn Subject Matter Content, Develop and Practice Critical Reasoning Skills, and Reflect on Personal Values in Food Science and Human Nutrition Classes

    Science.gov (United States)

    Iwaoka, Wayne T.; Crosetti, Lea M.

    2008-01-01

    It has been reported that students learn best when they use a wide variety of techniques to understand the information of the discipline, be it visual, auditory, discussion with others, metacognition, hands-on activities, or writing about the subject. We report in this article the use of academic journals not only as an aid for students to learn…

  18. A Structural Equation Model Analyzing the Relationship of Student Achievement Motivations and Personality Factors in a Range of Academic Subject-Matter Areas

    Science.gov (United States)

    Tempelaar, Dirk T.; Gijselaers, Wim H.; Schim van der Loeff, Sybrand; Nijhuis, Jan F. H.

    2007-01-01

    The question of subject-specificity of achievement motivations is important, both for educational psychology, as well as for educational policy. This study contributes to the investigation of the heterogeneity in achievement motivations in the context of the expectancy-value model. Whereas existing research deals with middle and high school…

  19. White matter organization in relation to upper limb motor control in healthy subjects: exploring the added value of diffusion kurtosis imaging.

    Science.gov (United States)

    Gooijers, J; Leemans, A; Van Cauter, S; Sunaert, S; Swinnen, S P; Caeyenberghs, K

    2014-09-01

    Diffusion tensor imaging (DTI) characterizes white matter (WM) microstructure. In many brain regions, however, the assumption that the diffusion probability distribution is Gaussian may be invalid, even at low b values. Recently, diffusion kurtosis imaging (DKI) was suggested to more accurately estimate this distribution. We explored the added value of DKI in studying the relation between WM microstructure and upper limb coordination in healthy controls (N = 24). Performance on a complex bimanual tracking task was studied with respect to the conventional DTI measures (DKI or DTI derived) and kurtosis metrics of WM tracts/regions carrying efferent (motor) output from the brain, corpus callosum (CC) substructures and whole brain WM. For both estimation models, motor performance was associated with fractional anisotropy (FA) of the CC-genu, CC-body, the anterior limb of the internal capsule, and whole brain WM (r s range 0.42-0.63). Although DKI revealed higher mean, radial and axial diffusivity and lower FA than DTI (p motor performance was associated with increased mean and radial kurtosis and kurtosis anisotropy (r s range 0.43-0.55). In conclusion, DKI provided additional information, but did not show increased sensitivity to detect relations between WM microstructure and bimanual performance in healthy controls.

  20. Dark matter an introduction

    CERN Document Server

    Majumdar, Debasish

    2015-01-01

    Dark Matter: An Introduction tackles the rather recent but fast-growing subject of astroparticle physics, encompassing three main areas of fundamental physics: cosmology, particle physics, and astrophysics. Accordingly, the book discusses symmetries, conservation laws, relativity, and cosmological parameters and measurements, as well as the astrophysical behaviors of galaxies and galaxy clusters that indicate the presence of dark matter and the possible nature of dark matter distribution.

  1. Macro Dark Matter

    CERN Document Server

    Jacobs, David M; Lynn, Bryan W.

    2015-01-01

    Dark matter is a vital component of the current best model of our universe, $\\Lambda$CDM. There are leading candidates for what the dark matter could be (e.g. weakly-interacting massive particles, or axions), but no compelling observational or experimental evidence exists to support these particular candidates, nor any beyond-the-Standard-Model physics that might produce such candidates. This suggests that other dark matter candidates, including ones that might arise in the Standard Model, should receive increased attention. Here we consider a general class of dark matter candidates with characteristic masses and interaction cross-sections characterized in units of grams and cm$^2$, respectively -- we therefore dub these macroscopic objects as Macros. Such dark matter candidates could potentially be assembled out of Standard Model particles (quarks and leptons) in the early universe. A combination of earth-based, astrophysical, and cosmological observations constrain a portion of the Macro parameter space; ho...

  2. Respiratory effects of particulate matter air pollution: studies on diesel exhaust, road tunnel, subway and wood smoke exposure in human subjects

    Energy Technology Data Exchange (ETDEWEB)

    Sehlstedt, Maria

    2011-07-01

    Background: Ambient air pollution is associated with adverse health effects, but the sources and components, which cause these effects is still incompletely understood. The aim of this thesis was to investigate the pulmonary effects of a variety of common air pollutants, including diesel exhaust, biomass smoke, and road tunnel and subway station environments. Healthy non-smoking volunteers were exposed in random order to the specific air pollutants and air/control, during intermittent exercise, followed by bronchoscopy. Methods and results: In study I, exposures were performed with diesel exhaust (DE) generated at transient engine load and air for 1 hour with bronchoscopy at 6 hours post-exposure. Immunohistochemical analyses of bronchial mucosal biopsies showed that DE exposure significantly increased the endothelial adhesion molecule expression of p-selectin and VCAM-1, together with increased bronchoalveolar lavage (BAL) eosinophils. In study II, the subjects were exposed for 1 hour to DE generated during idling with bronchoscopy at 6 hours. The bronchial mucosal biopsies showed significant increases in neutrophils, mast cells and lymphocytes together with bronchial wash neutrophils. Additionally, DE exposure significantly increased the nuclear translocation of the aryl hydrocarbon receptor (AhR) and phosphorylated c-jun in the bronchial epithelium. In contrast, the phase II enzyme NAD(P)H-quinone oxidoreductase 1 (NQO1) decreased after DE. In study III, the 2-hour exposures took place in a road tunnel with bronchoscopy 14 hours later. The road tunnel exposure significantly increased the total numbers of lymphocytes and alveolar macrophages in BAL, whereas NK cell and CD56+/T cell numbers significantly decreased. Additionally, the nuclear expression of phosphorylated c-jun in the bronchial epithelium was significantly increased after road tunnel exposure. In study IV, the subjects were exposed to metal-rich particulate aerosol for 2 hours at a subway station

  3. The National Shipbuilding Program. Preliminary Impact Analysis of Proposed Revisions of National Ambient Air Quality Standard for Ozone and Particulate Matter

    National Research Council Canada - National Science Library

    1997-01-01

    ...) and particulate matter (PM). The analysis was performed to provide information to the U.S. ship building and ship repair industry, so that companies in that industry could determine whether to submit comments on these EPA proposals...

  4. Progressing towards more quantitative analytical pyrolysis of soil organic matter using molecular beam mass spectroscopy of whole soils and added standards

    Energy Technology Data Exchange (ETDEWEB)

    Haddix, Michelle L.; Magrini-Bair, Kim; Evans, Robert J.; Conant, Richard T.; Wallenstein, Matthew D.; Morris, Sherri J.; Calderón, Francisco; Paul, Eldor A.

    2016-12-01

    Soil organic matter (SOM) is extremely complex. It is composed of hundreds of different organic substances and it has been difficult to quantify these diverse substances in a dynamic-ecosystem functioning standpoint. Analytical pyrolysis has been used to compare chemical differences between soils, but its ability to measure the absolute amount of a specific compound in the soil is still in question. Our objective was to assess whether utilizing pyrolysis-molecular beam mass spectroscopy (py-MBMS) to define the signature of known reference compounds (adenine, indole, palmitic acid, etc.) and biological samples (chitin, fungi, cellulose, etc.) separately and when added to whole soils it was possible to make py-MBMS more quantitative. Reference compounds, spanning a wide variety of compound categories, and biological samples, expected to be present in SOM, were added to three soils from Colorado, Ohio, and Massachusetts that have varying total C, % clay, and clay type. Py-MBMS, a rapid analysis technique originally developed to analyze complex biomolecules, flash pyrolyzes soil organic matter to form products that are often considered characteristic of the original molecular structure. Samples were pyrolyzed at 550 degrees C by py-MBMS. All samples were weighed and %C and %N determined both before and after pyrolysis to evaluate mass loss, C loss, and N loss for the samples.An average relationship of r2 = 0.76 (P = 0.005) was found for the amount of cellulose added to soil at 25, 50, and 100% of soil C relative to the ion intensity of select mass/charge of the compound.There was a relationship of r2 = 0.93 (P < 0.001) for the amount of indole added to soil at 25, 50, and 100% of soil C and the ion intensity of the associated mass variables (mass/charge). Comparing spectra of pure compounds with the spectra of the compounds added to soil and isolated clay showed that interference could occur based on soil type and compound with the Massachusetts soil with high C (55

  5. Do CS-US pairings actually matter? A within-subject comparison of instructed fear conditioning with and without actual CS-US pairings.

    Directory of Open Access Journals (Sweden)

    An K Raes

    Full Text Available Previous research showed that instructions about CS-US pairings can lead to fear of the CS even when the pairings are never presented. In the present study, we examined whether the experience of CS-US pairings adds to the effect of instructions by comparing instructed conditioning with and without actual CS-US pairings in a within-subject design. Thirty-two participants saw three fractals as CSs (CS(+1, CS(+2, CS(- and received electric shocks as USs. Before the start of a so-called training phase, participants were instructed that both CS(+1 and CS(+2 would be followed by the US, but only CS(+1 was actually paired with the US. The absence of the US after CS(+2 was explained in such a way that participants would not doubt the instructions about the CS(+2-US relation. After the training phase, a test phase was carried out. In this phase, participants expected the US after both CS(+s but none of the CS(+s was actually paired with the US. During test, self-reported fear was initially higher for CS(+1 than for CS(+2, which indicates that the experience of actual CS-US pairings adds to instructions about these pairings. On the other hand, the CS(+s elicited similar skin conductance responses and US expectancies. Theoretical and clinical implications are discussed.

  6. Common Core State Standards for English Language Arts & Literacy in History/Social Studies, Science, and Technical Subjects. Appendix B: Text Exemplars and Sample Performance Tasks

    Science.gov (United States)

    Common Core State Standards Initiative, 2010

    2010-01-01

    The text samples presented in this document primarily serve to exemplify the level of complexity and quality that the Standards require all students in a given grade band to engage with. Additionally, they are suggestive of the breadth of texts that students should encounter in the text types required by the Standards. The choices should serve as…

  7. Common Core State Standards for English Language Arts & Literacy in History/Social Studies, Science, and Technical Subjects. Appendix C: Samples of Student Writing

    Science.gov (United States)

    Common Core State Standards Initiative, 2010

    2010-01-01

    This document presents writing samples that have been annotated to illustrate the criteria required to meet the Common Core State Standards for particular types of writing--argument, informative/explanatory text, and narrative--in a given grade. Each of the samples exhibits at least the level of quality required to meet the Writing standards for…

  8. Benefits of multi-modal fusion analysis on a large-scale dataset: life-span patterns of inter-subject variability in cortical morphometry and white matter microstructure.

    Science.gov (United States)

    Groves, Adrian R; Smith, Stephen M; Fjell, Anders M; Tamnes, Christian K; Walhovd, Kristine B; Douaud, Gwenaëlle; Woolrich, Mark W; Westlye, Lars T

    2012-10-15

    Neuroimaging studies have become increasingly multimodal in recent years, with researchers typically acquiring several different types of MRI data and processing them along separate pipelines that provide a set of complementary windows into each subject's brain. However, few attempts have been made to integrate the various modalities in the same analysis. Linked ICA is a robust data fusion model that takes multi-modal data and characterizes inter-subject variability in terms of a set of multi-modal components. This paper examines the types of components found when running Linked ICA on a large magnetic resonance imaging (MRI) morphometric and diffusion tensor imaging (DTI) data set comprising 484 healthy subjects ranging from 8 to 85 years of age. We find several strong global features related to age, sex, and intracranial volume; in particular, one component predicts age to a high accuracy (r=0.95). Most of the remaining components describe spatially localized modes of variability in white or gray matter, with many components including both tissue types. The multimodal components tend to be located in anatomically-related brain areas, suggesting a morphological and possibly functional relationship. The local components show relationships between surface-based cortical thickness and arealization, voxel-based morphometry (VBM), and between three different DTI measures. Further, we report components related to artifacts (e.g. scanner software upgrades) which would be expected in a dataset of this size. Most of the 100 extracted components showed interpretable spatial patterns and were found to be reliable using split-half validation. This work provides novel information about normal inter-subject variability in brain structure, and demonstrates the potential of Linked ICA as a feature-extracting data fusion approach across modalities. This exploratory approach automatically generates models to explain structure in the data, and may prove especially powerful for large

  9. Does the Standard-Setter's Opinion Matter? An Analysis of the Impact of the IASB Letter's Disclosure on the Stock Returns of European Banks with Greek Bond Exposure

    National Research Council Canada - National Science Library

    Cristina Zardo Calvi; Fernando Caio Galdi

    2014-01-01

      This study investigates whether there is evidence that the letter issued and disclosed to the market by the international accounting standard-setter the International Accounting Standards Board (IASB...

  10. The Problem of Subject Access to Visual Materials

    Directory of Open Access Journals (Sweden)

    Heather P. Jespersen

    2004-09-01

    Full Text Available This article discusses the problem of giving subject access to works of art. We survey both concept-based and content-based access by computers and by indexers/catalogers respectively, as well as issues of interoperability, database and indexer consistency, and cataloging standards. The authors, both of whom are trained art historians, question attempts to mystify fine art subject matter by the creation of clever library science systems that are executed by the naive. Only when trained art historians and knowledgeable catalogers are finally responsible for providing subject access to works of art, will true interoperability and consistency happen.

  11. The effect of the 4MAT learning model on the achievement and motivation of 7th grade students on the subject of particulate nature of matter and an examination of student opinions on the model

    Science.gov (United States)

    Aktas, İdris; Bılgın, İbrahim

    2015-01-01

    Background:Many researchers agree that students, especially primary students, have learning difficulties on the 'Particulate Nature of Matter' unit. One reason for this difficulty is not considering individual differences for teaching science. In 4MAT model learning, environment is arranged according to individual differences. Purpose:The purpose of this study is to examine (1) the effects of the 4MAT learning model on the7th grade students' academic achievement and motivation on the 'Particulate Nature of Matter' unit and (2) identify student opinions on the 4MAT model. Sample:The sample consists of 235 students (115 experimental, 120 control) in Turkey. Design and methods:Experimental groups were instructed with the 4MAT model while control groups were instructed with a traditional method. Achievement Test (AchToM) and Motivation Scale (MotScl) were administered to students as pre- and post-tests. Moreover, the opinions of students in the experimental groups on the 4MAT model were ascertained through open-ended questions after the application. Results:According to independent t-test results, statistical difference in favour of the experimental groups was detected between the post-AchToM (ES = 1.43; p motivation and participation in the lesson, lessons are more amusing and enjoyable, and the self-confidence of the students increases. Besides these positive opinions, however, a few students stated that the method took too much time, they were not motivated and it did not help them in understanding the subject. Conclusions:The 4MAT model is more effective than traditional method in terms of increasing achievement and motivation. The model takes all learners into account. Thus, the teacher or educator should use the 4MAT model to ensure all students' learning in their classroom.

  12. Tamoxifen effects on subjective and psychosexual well-being, in a randomised breast cancer study comparing high-dose and standard-dose chemotherapy

    NARCIS (Netherlands)

    Mourits, MJ; Bockermann, [No Value; de Vries, EG; van der Zee, AG; ten Hoor, KA; van der Graaf, WT; Sluiter, WJ; Willemse, PH

    2002-01-01

    To evaluate the impact of tamoxifen on subjective and psychosexual well-being in breast cancer patients in relation to type of prior chemotherapy and menopausal status. Longitudinal interview study in breast cancer patients during and after adjuvant tamoxifen use. Menopausal status was defined by

  13. Robustness of parameter and standard error estimates against ignoring a contextual effect of a subject level covariate in cluster randomized trials

    NARCIS (Netherlands)

    Korendijk, E.J.H.; Hox, J.; Moerbeek, M.

    2011-01-01

    In experimental research, it is not uncommon to assign clusters to conditions.When analysing the data of such cluster-randomized trials, a multilevel analysis should be applied in order to take into account the dependency of firstlevel units (i.e., subjects) within a second-level unit (i.e., a

  14. Two Higgs doublet dark matter portal

    Science.gov (United States)

    Bell, Nicole F.; Busoni, Giorgio; Sanderson, Isaac W.

    2018-01-01

    We study a fermionic dark matter model in which the interaction of the dark and visible sectors is mediated by Higgs portal type couplings. Specifically, we consider the mixing of a dark sector scalar with the scalars of a Two Higgs Doublet Model extension of the Standard Model. Given that scalar exchange will result in a spin-independent dark matter-nucleon scattering cross section, such a model is potentially subject to stringent direct detection constraints. Moreover, the addition of new charged scalars introduce non-trivial flavour constraints. Nonetheless, this model allows more freedom than a standard Higgs portal scenario involving a single Higgs doublet, and much of the interesting parameter space is not well approximated by a Simplified Model with a single scalar mediator. We perform a detailed parameter scan to determine the mass and coupling parameters which satisfy direct detection, flavour, precision electroweak, stability, and perturbativity constraints, while still producing the correct relic density through thermal freezeout.

  15. Cosmetology. Subject Matters, Volume 3, No. 3.

    Science.gov (United States)

    Reese, Susan

    2001-01-01

    "The Beauty of Cosmetology" discusses the employment outlook for cosmetologists. "High School Cosmetology with Great Style" describes the academic and career cosmetology curriculum at Great Oaks Institute of Technology and Career Development (Ohio). "More than Skin Deep" explores the job shadowing program at the American Academy of Hair Design.…

  16. Digital Literacy and Subject Matter Learning

    DEFF Research Database (Denmark)

    Levinsen, Karin; Sørensen, Birgitte Holm

    2015-01-01

    It is generally agreed that learners need to acquire digital literacy in order to be able to act as citizens, employees and entrepreneurs in an increasingly digitalized environment. It is also generally agreed that the educational system has to be responsible for educating towards digital literacy....... However, there is no shared conception of the scope and meaning of digital literacy. The overall picture shows two main approaches: The first aims at digital literacy in the sense of Buildung (general education) while the second addresses a wide range of specific skills and competences: From basic...... computer skills over multimodal analysis to social conventions for behavior in online environments. Consequently designs for teaching and learning that aim at learners acquiring digital literacy and the related learning objectives appear as weak defined. According to the Danish Ministry of Education Shared...

  17. Language and Composition: Does the Subject Matter?

    Science.gov (United States)

    Alexis, Gerhard T.

    1968-01-01

    Attempts to combine language and composition in the freshman English course at Gustavus Adolphus College (St. Peter, Minnesota) should interest all teachers of English. One project utilized a single key word for several assignments. Students were asked to (1) think through the meaning of the word for a week and write definitions and associations,…

  18. Meeting the Challenge: Teaching Sensitive Subject Matter

    Science.gov (United States)

    Crosby, Dorian B.

    2012-01-01

    When teaching diversity courses that discuss sensitive issues, such as racial, gender, sexuality, religious, and ethnic discrimination, it is possible to encounter student resistance, which can subsequently prevent students from comprehending the content. While teaching an introductory course on African American history in a Black Studies…

  19. Student Center Activities Aligned to the Common Core State Standards in English Language Arts and Literacy in History/Social Studies, Science, and Technical Subjects K-5

    Science.gov (United States)

    Verhagen, Connie

    2012-01-01

    This publication helps educators create differentiated reading instruction experiences for their students by showing the relationship between two distinct resources: Student Center Activities (SCAs) and the Common Core State Standards (CCSSs). Reading specialists, reading coaches, and teachers will find this document useful in lesson planning, as…

  20. Gray Matter Concentration Abnormality in Brains of Narcolepsy Patients

    Energy Technology Data Exchange (ETDEWEB)

    Joo, Eun Yeon; Tae, Woo Suk; Kim, Sung Tae; Hong, Seung Bong [Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2009-12-15

    To investigate gray matter concentration changes in the brains of narcoleptic patients. Twenty-nine narcoleptic patient with cataplexy and 29 age and sex-matched normal subjects (mean age, 31 years old) underwent volumetric MRIs. The MRIs were spatially normalized to a standard T1 template and subdivided into gray matter, white matter, and cerebrospinal fluid (CSF). These segmented images were then smoothed using a 12-mm full width at half maximum (FWHM) isotropic Gaussian kernel. An optimized voxel-based morphometry protocol was used to analyze brain tissue concentrations using SPM2 (statistical parametric mapping). A one-way analysis of variance was applied to the concentration analysis of gray matter images. Narcoleptics with cataplexy showed reduced gray matter concentration in bilateral thalami, left gyrus rectus, bilateral frontopolar gyri, bilateral short insular gyri, bilateral superior frontal gyri, and right superior temporal and left inferior temporal gyri compared to normal subjects (uncorrected p < 0.001). Furthermore, small volume correction revealed gray matter concentration reduction in bilateral nuclei accumbens, hypothalami, and thalami (false discovery rate corrected p < 0.05). Gray matter concentration reductions were observed in brain regions related to excessive daytime sleepiness, cognition, attention, and memory in narcoleptics with cataplexy

  1. Optimizing preprocessing and analysis pipelines for single-subject fMRI. I. Standard temporal motion and physiological noise correction methods.

    Science.gov (United States)

    Churchill, Nathan W; Oder, Anita; Abdi, Hervé; Tam, Fred; Lee, Wayne; Thomas, Christopher; Ween, Jon E; Graham, Simon J; Strother, Stephen C

    2012-03-01

    Subject-specific artifacts caused by head motion and physiological noise are major confounds in BOLD fMRI analyses. However, there is little consensus on the optimal choice of data preprocessing steps to minimize these effects. To evaluate the effects of various preprocessing strategies, we present a framework which comprises a combination of (1) nonparametric testing including reproducibility and prediction metrics of the data-driven NPAIRS framework (Strother et al. [2002]: NeuroImage 15:747-771), and (2) intersubject comparison of SPM effects, using DISTATIS (a three-way version of metric multidimensional scaling (Abdi et al. [2009]: NeuroImage 45:89-95). It is shown that the quality of brain activation maps may be significantly limited by sub-optimal choices of data preprocessing steps (or "pipeline") in a clinical task-design, an fMRI adaptation of the widely used Trail-Making Test. The relative importance of motion correction, physiological noise correction, motion parameter regression, and temporal detrending were examined for fMRI data acquired in young, healthy adults. Analysis performance and the quality of activation maps were evaluated based on Penalized Discriminant Analysis (PDA). The relative importance of different preprocessing steps was assessed by (1) a nonparametric Friedman rank test for fixed sets of preprocessing steps, applied to all subjects; and (2) evaluating pipelines chosen specifically for each subject. Results demonstrate that preprocessing choices have significant, but subject-dependant effects, and that individually-optimized pipelines may significantly improve the reproducibility of fMRI results over fixed pipelines. This was demonstrated by the detection of a significant interaction with motion parameter regression and physiological noise correction, even though the range of subject head motion was small across the group (≪ 1 voxel). Optimizing pipelines on an individual-subject basis also revealed brain activation patterns

  2. When Matter Matters

    CERN Document Server

    Easson, Damien A.; Vikman, Alexander

    2013-07-10

    We study a recently proposed scenario for the early universe: Subluminal Galilean Genesis. We prove that without any other matter present in the spatially flat Friedmann universe, the perturbations of the Galileon scalar field propagate with a speed at most equal to the speed of light. This proof applies to all cosmological solutions -- to the whole phase space. However, in a more realistic situation, when one includes any matter which is not directly coupled to the Galileon, there always exists a region of phase space where these perturbations propagate superluminally, indeed with arbitrarily high speed. We illustrate our analytic proof with numerical computations. We discuss the implications of this result for the possible UV completion of the model.

  3. DEVELOPING ‘STANDARD NOVEL ‘VAD’ TECHNIQUE’ AND ‘NOISE FREE SIGNALS’ FOR SPEECH AUDITORY BRAINSTEM RESPONSES FOR HUMAN SUBJECTS

    OpenAIRE

    Ranganadh Narayanam

    2016-01-01

    In this research as a first step we have concentrated on collecting non-intra cortical EEG data of Brainstem Speech Evoked Potentials from human subjects in an Audiology Lab in University of Ottawa. The problems we have considered are the most advanced and most essential problems of interest in Auditory Neural Signal Processing area in the world: The first problem is the Voice Activity Detection (VAD) in Speech Auditory Brainstem Responses (ABR); The second problem is to identify the best De-...

  4. High variability of the subjective visual vertical test of vertical perception, in some people with neck pain - Should this be a standard measure of cervical proprioception?

    Science.gov (United States)

    Treleaven, Julia; Takasaki, Hiroshi

    2015-02-01

    Subjective visual vertical (SVV) assesses visual dependence for spacial orientation, via vertical perception testing. Using the computerized rod-and-frame test (CRFT), SVV is thought to be an important measure of cervical proprioception and might be greater in those with whiplash associated disorder (WAD), but to date research findings are inconsistent. The aim of this study was to investigate the most sensitive SVV error measurement to detect group differences between no neck pain control, idiopathic neck pain (INP) and WAD subjects. Cross sectional study. Neck Disability Index (NDI), Dizziness Handicap Inventory short form (DHIsf) and the average constant error (CE), absolute error (AE), root mean square error (RMSE), and variable error (VE) of the SVV were obtained from 142 subjects (48 asymptomatic, 36 INP, 42 WAD). The INP group had significantly (p proprioception in neck pain and more research is required before the SVV can be considered an important measure and utilized clinically. Crown Copyright © 2014. Published by Elsevier Ltd. All rights reserved.

  5. 76 FR 38396 - Notice of Availability of Proposed Data Collection Standards for Race, Ethnicity, Primary...

    Science.gov (United States)

    2011-06-30

    ... INFORMATION: Introduction DHHS reports, dating back to the landmark 1985 Secretary's Task Force on Black and... that any DHHS data standards be in compliance with standards created by the Office of Management and..., and the expertise of subject matter experts who have leadership roles with collecting and analyzing...

  6. Common Core State Standards for English Language Arts & Literacy in History/Social Studies, Science, and Technical Subjects. Appendix A: Research Supporting Key Elements of the Standards, Glossary of Key Terms

    Science.gov (United States)

    Common Core State Standards Initiative, 2010

    2010-01-01

    One of the key requirements of the Common Core State Standards for Reading is that all students must be able to comprehend texts of steadily increasing complexity as they progress through school. By the time they complete the core, students must be able to read and comprehend independently and proficiently the kinds of complex texts commonly found…

  7. Solid Matter

    CERN Document Server

    Angelo, Joseph A

    2011-01-01

    Supported by a generous quantity of full-color illustrations and interesting sidebars, Solid Matter introduces the basic characteristics and properties of solid matter. It briefly describes the cosmic connection of the elements, leading readers through several key events in human pre-history that resulted in more advanced uses of matter in the solid state. Chapters include:. -Solid Matter: An Initial Perspective. -Physical Behavior of Matter. -The Gravity of Matter. -Fundamentals of Materials Science. -Rocks and Minerals. -Metals. -Building Materials. -Carbon Earth's Most Versatile Element. -S

  8. The brain subcortical white matter and aging: A quantitative fractional anisotropy analysis

    Directory of Open Access Journals (Sweden)

    Eliasz Engelhardt

    Full Text Available Abstract To study the integrity of hemispheric subcortical white matter by comparing normal young and elderly subjects using quantitative fractional anisotropy (DTI-FA. Methods: Subjects of two different age groups (young=12, elderly=12 were included. MR - GE Signa Horizon - 1.5T scans were performed. Cases with Fazekas scores £3 were assessed on FLAIR sequence. Standard parameters for DTI-FA were used. ROIs were placed at various sites of the subcortical white matter, and the genu and splenium of the midline corpus callosum. Analysis was performed using Functool. Statistics for anterior and posterior white matter, as well as the genu and splenium were compared between the groups. The study was approved by the Ethics Committee of IPUB-UFRJ and informed consent obtained. Results: DTI-FA showed lower anisotropy values in the anterior region (subcortical white matter and genu, but not in the posterior region (subcortical white matter and splenium, in elderly normal subjects compared to young subjects. Conclusion: The results may represent loss of integrity of anterior (frontal white matter fibers in the elderly subjects. These fibers constitute important intra- and inter-hemispheric tracts, components of neural networks that provide cognitive, behavioral, motor and sensory integration. The loss of integrity of the anterior segments of the studied fiber systems with ageing, represents a disconnection process that may underlie clinical manifestations found in elderly subjects such as executive dysfunction.

  9. Common standards in facial esthetics: craniofacial analysis of most attractive black and white subjects according to People magazine during previous 10 years.

    Science.gov (United States)

    Iglesias-Linares, Alejandro; Yáñez-Vico, Rosa-María; Moreno-Manteca, Blanca; Moreno-Fernández, Ana María; Mendoza-Mendoza, Asunción; Solano-Reina, Enrique

    2011-06-01

    The aim of the present case-control study was to determine--using the 10 most recent annual listings of the most beautiful black and white people--whether any common, measurable esthetic parameter could be extracted from both groups. A total of 80 women (40 white and 40 black), who had been included in the list of People magazine's 100 most beautiful people during the previous 10 years, were selected. Lateral photographs of all 80 subjects were obtained from Internet databases, oriented, and sized. A modified photogrammetric analysis was performed on the lateral view of each subject to obtain the angle and proportion measurements. Differences between the 2 groups were compared with 95% significance using the Student t test for independent samples. Facial similarities in the 2 ethnic groups were observed for the angle of the inferior facial third, labiomental angle, angle of facial convexity, and cervicomental angle. These results point to a similar conformation of the lower part of the face in relation to the neck that was shared by both groups of beautiful women. Additionally, both groups showed similar results for the lower lip projection. Likewise, similar proportional measurements were found for the upper lip proportion, notwithstanding differences in protrusion. Modern society is changing the classic concept of facial beauty because of globalization and the prevalence of multiethnic communities in the developed world. Independently of ethnic origin, beautiful women tend to have similar facial features that are a mixture of both black and white features. Copyright © 2011 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  10. Speech Matters

    DEFF Research Database (Denmark)

    Hasse Jørgensen, Stina

    2011-01-01

    About Speech Matters - Katarina Gregos, the Greek curator's exhibition at the Danish Pavillion, the Venice Biannual 2011.......About Speech Matters - Katarina Gregos, the Greek curator's exhibition at the Danish Pavillion, the Venice Biannual 2011....

  11. Stellar dynamics in the strong-lensing central galaxy of Abell 1201: a low stellar mass-to-light ratio, a large central compact mass and a standard dark matter halo

    Science.gov (United States)

    Smith, Russell J.; Lucey, John R.; Edge, Alastair C.

    2017-10-01

    We analyse the stellar kinematics of the z = 0.169 brightest cluster galaxy in Abell 1201, using integral field observations acquired with the Multi-Unit Spectroscopic Explorer on the Very Large Telescope. This galaxy has a gravitationally lensed arc located at unusually small radius (˜5 kpc), allowing us to constrain the mass distribution using lensing and stellar dynamical information over the same radial range. We measure a velocity dispersion profile which is nearly flat at σ ≈ 285 km s-1 in the inner ˜5 kpc, and then rises steadily to σ ≈ 360 km s-1 at ˜30 kpc. We analyse the kinematics using axisymmetric Jeans models, finding that the data require both a significant dark matter halo (to fit the rising outer profile) and a compact central component, with mass Mcen ≈ 2.5 × 1010 M⊙ (to fit the flat σ in the inner regions). The latter component could represent a supermassive black hole, in which case it would be among the largest known to date. Alternatively Mcen could describe excess mass associated with a gradient in the stellar mass-to-light ratio. Imposing a standard Navarro-Frenk-White (NFW) dark matter density profile, we recover a stellar mass-to-light ratio ϒ, which is consistent with a Milky Way-like initial mass function (IMF). By anchoring the models using the lensing mass constraint, we break the degeneracy between ϒ and the inner slope γ of the dark matter profile, finding γ = 1.0 ± 0.1, consistent with the NFW form. We show that our results are quite sensitive to the treatment of the central mass in the models. Neglecting Mcen biases the results towards both a heavier-than-Salpeter IMF and a shallower-than-NFW dark matter slope (γ ≈ 0.5).

  12. Dark Matter

    Indian Academy of Sciences (India)

    matter and that it must be of some exotic type. Before we discuss the evidences for dark matter in clusters of galaxies, let us point out that it is not just spiral galaxies which are thought to contain dark matter, although the evidences from them are the strongest. Other types of galaxies, like elliptical galaxies, are often seen to ...

  13. Standard errors and confidence intervals in within-subjects designs: generalizing Loftus and Masson (1994) and avoiding the biases of alternative accounts.

    Science.gov (United States)

    Franz, Volker H; Loftus, Geoffrey R

    2012-06-01

    Repeated measures designs are common in experimental psychology. Because of the correlational structure in these designs, the calculation and interpretation of confidence intervals is nontrivial. One solution was provided by Loftus and Masson (Psychonomic Bulletin & Review 1:476-490, 1994). This solution, although widely adopted, has the limitation of implying same-size confidence intervals for all factor levels, and therefore does not allow for the assessment of variance homogeneity assumptions (i.e., the circularity assumption, which is crucial for the repeated measures ANOVA). This limitation and the method's perceived complexity have sometimes led scientists to use a simplified variant, based on a per-subject normalization of the data (Bakeman & McArthur, Behavior Research Methods, Instruments, & Computers 28:584-589, 1996; Cousineau, Tutorials in Quantitative Methods for Psychology 1:42-45, 2005; Morey, Tutorials in Quantitative Methods for Psychology 4:61-64, 2008; Morrison & Weaver, Behavior Research Methods, Instruments, & Computers 27:52-56, 1995). We show that this normalization method leads to biased results and is uninformative with regard to circularity. Instead, we provide a simple, intuitive generalization of the Loftus and Masson method that allows for assessment of the circularity assumption.

  14. Estimation of spatial-temporal gait parameters in level walking based on a single accelerometer: validation on normal subjects by standard gait analysis.

    Science.gov (United States)

    Bugané, F; Benedetti, M G; Casadio, G; Attala, S; Biagi, F; Manca, M; Leardini, A

    2012-10-01

    This paper investigates the ability of a single wireless inertial sensing device stuck on the lower trunk to provide spatial-temporal parameters during level walking. The 3-axial acceleration signals were filtered and the timing of the main gait events identified. Twenty-two healthy subjects were analyzed with this system for validation, and the estimated parameters were compared with those obtained with state-of-the-art gait analysis, i.e. stereophotogrammetry and dynamometry. For each side, from four to six gait cycles were measured with the device, of which two were validated by gait analysis. The new acquisition system is easy to use and does not interfere with regular walking. No statistically significant differences were found between the acceleration-based measurements and the corresponding ones from gait analysis for most of the spatial-temporal parameters, i.e. stride length, stride duration, cadence and speed, etc.; significant differences were found for the gait cycle phases, i.e. single and double support duration, etc. The system therefore shows promise also for a future routine clinical use. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  15. Particle Size-Selective Assessment of Protection of European Standard FFP Respirators and Surgical Masks against Particles-Tested with Human Subjects

    Directory of Open Access Journals (Sweden)

    Shu-An Lee

    2016-01-01

    Full Text Available This study was conducted to investigate the protection of disposable filtering half-facepiece respirators of different grades against particles between 0.093 and 1.61 μm. A personal sampling system was used to particle size-selectively assess the protection of respirators. The results show that about 10.9% of FFP2 respirators and 28.2% of FFP3 respirators demonstrate assigned protection factors (APFs below 10 and 20, which are the levels assigned for these respirators by the British Standard. On average, the protection factors of FFP respirators were 11.5 to 15.9 times greater than those of surgical masks. The minimum protection factors (PFs were observed for particles between 0.263 and 0.384 μm. No significant difference in PF results was found among FFP respirator categories and particle size. A strong association between fit factors and protection factors was found. The study indicates that FFP respirators may not achieve the expected protection level and the APFs may need to be revised for these classes of respirators.

  16. Particle Size-Selective Assessment of Protection of European Standard FFP Respirators and Surgical Masks against Particles-Tested with Human Subjects.

    Science.gov (United States)

    Lee, Shu-An; Hwang, Dong-Chir; Li, He-Yi; Tsai, Chieh-Fu; Chen, Chun-Wan; Chen, Jen-Kun

    2016-01-01

    This study was conducted to investigate the protection of disposable filtering half-facepiece respirators of different grades against particles between 0.093 and 1.61  μm. A personal sampling system was used to particle size-selectively assess the protection of respirators. The results show that about 10.9% of FFP2 respirators and 28.2% of FFP3 respirators demonstrate assigned protection factors (APFs) below 10 and 20, which are the levels assigned for these respirators by the British Standard. On average, the protection factors of FFP respirators were 11.5 to 15.9 times greater than those of surgical masks. The minimum protection factors (PFs) were observed for particles between 0.263 and 0.384  μm. No significant difference in PF results was found among FFP respirator categories and particle size. A strong association between fit factors and protection factors was found. The study indicates that FFP respirators may not achieve the expected protection level and the APFs may need to be revised for these classes of respirators.

  17. Comparison of mobility and user satisfaction between a microprocessor knee and a standard prosthetic knee: a summary of seven single-subject trials.

    Science.gov (United States)

    Howard, Charla L; Wallace, Chris; Perry, Bonnie; Stokic, Dobrivoje S

    2018-03-01

    Insufficient evidence of the benefits provided by costlier microprocessor knees (MPKs) over nonmicroprocessor knees (NMPKs) often causes concern when considering MPK prescription. Thus, more studies are needed to demonstrate differences between MPKs and NMPKs and define sensitive outcomes to guide MPK prescription. The aim of this study was to evaluate the impact of switching from NMPK to MPK on measures of mobility and preference. Seven long-term NMPK users (all men, ages 50-84, 3-64 years postamputation) participated in this study, which use a single-subject design (ABA or BAB; A=NMPK, B=MPK). Mobility was assessed with the Amputee Mobility Predictor, Berg Balance Scale (BBS), L-Test, 6-Min Walk Test (6MWT) with Physiological Cost Index, and self-selected normal and very fast gait speeds. The preference between NMPK and MPK was evaluated by the Prosthesis Evaluation Questionnaire (PEQ) and the visual analog scale. Mobility improved with the MPK in six of seven participants, which was most often captured with BBS (median: +6 points) and 6MWT (median: +63 m). These improvements typically exceeded minimal clinically important difference or minimal detectable change thresholds. Most participants scored the MPK higher on the PEQ (median: +20 points) and six of seven expressed a global preference toward MPK. In the BAB group, the Amputee Mobility Predictor and BBS correlated with perception of change on several PEQ domains (Ρ≥0.59). In conclusion, MPKs may provide better outcomes and user satisfaction, particularly in those with lower mobility function. BBS and 6MWT were found to be the most sensitive measures to capture changes in mobility while using MPK for several weeks.

  18. The Subjectivity of Participation

    DEFF Research Database (Denmark)

    Nissen, Morten

    What is a 'we' – a collective – and how can we use such communal self-knowledge to help people? This book is about collectivity, participation, and subjectivity – and about the social theories that may help us understand these matters. It also seeks to learn from the innovative practices and ideas...... practices. Through this dialogue, it develops an original trans-disciplinary critical theory and practice of collective subjectivity for which the ongoing construction and overcoming of common sense, or ideology, is central. It also points to ways of relating discourse with agency, and fertilizing insights...... from interactionism and ideology theories in a cultural-historical framework....

  19. Inflatable Dark Matter.

    Science.gov (United States)

    Davoudiasl, Hooman; Hooper, Dan; McDermott, Samuel D

    2016-01-22

    We describe a general scenario, dubbed "inflatable dark matter," in which the density of dark matter particles can be reduced through a short period of late-time inflation in the early Universe. The overproduction of dark matter that is predicted within many, otherwise, well-motivated models of new physics can be elegantly remedied within this context. Thermal relics that would, otherwise, be disfavored can easily be accommodated within this class of scenarios, including dark matter candidates that are very heavy or very light. Furthermore, the nonthermal abundance of grand unified theory or Planck scale axions can be brought to acceptable levels without invoking anthropic tuning of initial conditions. A period of late-time inflation could have occurred over a wide range of scales from ∼MeV to the weak scale or above, and could have been triggered by physics within a hidden sector, with small but not necessarily negligible couplings to the standard model.

  20. Dark matter searches with CMS

    CERN Document Server

    Jeitler, Manfred

    2016-01-01

    The existence of dark matter, indicated by astronomical observations, is one of the main proofs of physics beyond the standard model. Despite its abundance, dark matter has not been directly observed yet. This talk presents several searches for dark matter production in proton-proton collisions at 7, 8, and 13 TeV at the LHC, performed by the CMS collaboration. They are interpreted in terms of simplified models with different structures and mediators, as well as generic effective theory terms.

  1. Natural minimal dark matter

    CERN Document Server

    Fabbrichesi, Marco

    2016-01-01

    We show how the Higgs boson mass is protected from the potentially large corrections due to the introduction of minimal dark matter if the new physics sector is made supersymmetric. The fermionic dark matter candidate (a 5-plet of $SU(2)_L$) is accompanied by a scalar state. The weak gauge sector is made supersymmetric and the Higgs boson is embedded in a supersymmetric multiplet. The remaining standard model states are non-supersymmetric. Non vanishing corrections to the Higgs boson mass only appear at three-loop level and the model is natural for dark matter masses up to 15 TeV--a value larger than the one required by the cosmological relic density. The construction presented stands as an example of a general approach to naturalness that solves the little hierarchy problem which arises when new physics is added beyond the standard model at an energy scale around 10 TeV.

  2. A voxel-based morphometric magnetic resonance imaging study of the brain detects age-related gray matter volume changes in healthy subjects of 21–45 years old

    Science.gov (United States)

    El-Beltagi, Ahmed; Cherian, Jigi; Gejo, Grace; Al-Jazzaf, Abrar; Ismail, Mohammad

    2015-01-01

    Previous and more recent work of analyzing structural changes in the brain suggest that certain brain regions such as the frontal lobe are among the brain regions profoundly affected by the aging process across males and females. Also, a unified model of structural changes in a normally aging brain is still lacking. The present study investigated age-related structural brain changes in gray matter from young to early middle-age adulthood for males and females. Magnetic resonance images of 215 normal and healthy participants between the ages of 21–45 years were acquired. Changes in gray matter were assessed using voxel-based morphometry and gray matter volumetric analysis. The results showed significant decrease in gray matter volume between the youngest and oldest groups in the following brain regions: frontal, temporal, and parietal lobes. Grey matter loss in the frontal lobe was among the most widespread of all brain regions across the comparison groups that showed significant age-related changes in grey matter for both males and females. This work provides a unique pattern of age-related decline of normal and healthy adult males and females that can aid in the future development of a unified model of normal brain aging. PMID:26306927

  3. A voxel-based morphometric magnetic resonance imaging study of the brain detects age-related gray matter volume changes in healthy subjects of 21-45 years old.

    Science.gov (United States)

    Bourisly, Ali K; El-Beltagi, Ahmed; Cherian, Jigi; Gejo, Grace; Al-Jazzaf, Abrar; Ismail, Mohammad

    2015-10-01

    Previous and more recent work of analyzing structural changes in the brain suggest that certain brain regions such as the frontal lobe are among the brain regions profoundly affected by the aging process across males and females. Also, a unified model of structural changes in a normally aging brain is still lacking. The present study investigated age-related structural brain changes in gray matter from young to early middle-age adulthood for males and females. Magnetic resonance images of 215 normal and healthy participants between the ages of 21-45 years were acquired. Changes in gray matter were assessed using voxel-based morphometry and gray matter volumetric analysis. The results showed significant decrease in gray matter volume between the youngest and oldest groups in the following brain regions: frontal, temporal, and parietal lobes. Grey matter loss in the frontal lobe was among the most widespread of all brain regions across the comparison groups that showed significant age-related changes in grey matter for both males and females. This work provides a unique pattern of age-related decline of normal and healthy adult males and females that can aid in the future development of a unified model of normal brain aging. © The Author(s) 2015.

  4. Template Composite Dark Matter

    DEFF Research Database (Denmark)

    Drach, Vincent; Hietanen, Ari; Pica, Claudio

    2015-01-01

    We present a non perturbative study of SU(2) gauge theory with two fundamental Dirac flavours. We discuss how the model can be used as a template for composite Dark Matter (DM). We estimate one particular interaction of the DM candidate with the Standard Model : the interaction through photon...

  5. with dark matter

    Indian Academy of Sciences (India)

    2012-11-16

    Nov 16, 2012 ... to have a dramatic impact on neutrino physics, dark matter and all fermion masses and mixings. Keywords. Radiative see-saw; fermion masses; grand unification. PACS Nos 12.10.Dm; 12.60.Jv; 14.60.Pq. 1. Introduction. In SO(10) grand unified theory which contains all standard fermions of one generation.

  6. Indirect searches for dark matter

    Indian Academy of Sciences (India)

    The current status of indirect searches for dark matter has been reviewed in a schematic way here. The main relevant experimental results of the recent years have been listed and the excitements and disappointments that their phenomenological interpretations in terms of almost-standard annihilating dark matter have ...

  7. Industry Matters

    DEFF Research Database (Denmark)

    Tran, Angie Ngoc; Jeppesen, Søren

    2018-01-01

    regulation and greater industry pressure with regard to quality and safety of products than to labour standards in both sectors. Most factories in the TGF sector assembled products for global supply chains and were under pressure by industry norms, while most companies in the FBP sector produced......This chapter draws on a study investigating what corporate social responsibility (CSR) means to Vietnam’s small- and medium-size enterprise (SME) owner/managers and workers, using Scott’s three-pillar (norms, regulation, cognition) institutional framework. The findings are based on factory visits...... for the domestic market and were subjected to greater state regulation. Moreover, contributing critical perspectives to Scott’s framework, we found an overlap between the normative and the regulatory, and between the cognitive and the industry norms, which reveals how institutional and cultural pressures...

  8. Enhancing Teacher Preparation and Improving Faculty Teaching Skills: Lessons Learned from Implementing ``Science That Matters'' a Standards Based Interdisciplinary Science Course Sequence

    Science.gov (United States)

    Potter, Robert; Meisels, Gerry

    2005-06-01

    In a highly collaborative process we developed an introductory science course sequence to improve science literacy especially among future elementary and middle school education majors. The materials and course features were designed using the results of research on teaching and learning to provide a rigorous, relevant and engaging, standard based science experience. More than ten years of combined planning, development, implementation and assessment of this college science course sequence for nonmajors/future teachers has provided significant insights and success in achieving our goal. This paper describes the history and iterative nature of our ongoing improvements, changes in faculty instructional practice, strategies used to overcome student resistance, significant student learning outcomes, support structures for faculty, and the essential and informative role of assessment in improving the outcomes. Our experience with diverse institutions, students and faculty provides the basis for the lessons we have learned and should be of help to others involved in advancing science education.

  9. Relative bioavailability of tizanidine 4-mg capsule and tablet formulations after a standardized high-fat meal: a single-dose, randomized, open-label, crossover study in healthy subjects.

    Science.gov (United States)

    Henney, Herbert R; Shah, Jaymin

    2007-04-01

    An immediate-release, multiparticulate capsule formulation of tizanidine has been developed to modify tizanidine pharmacokinetic characteristics in an attempt to decrease adverse events (AEs) while maintaining effectiveness in the management of spasticity. This study was designed to compare the pharmacokinetic properties and tolerability of a single dose (4 mg) of an immediate-release, multiparticulate tizanidine capsule versus a commercially available tablet (reference) administered after a standardized high-fat meal. This single-dose, randomized, open-label, 2-way crossover study in healthy, nonsmoking adult subjects was conducted at MDS Pharma Services, Belfast, United Kingdom. Subjects were randomly assigned to receive the capsule-tablet or tablet-capsule treatment. The 2 treatment periods were separated by a 6-day washout period. All treatments were administered after a standardized high-fat meal. To determine plasma tizanidine pharmacokinetic properties, blood samples were collected over 24 hours after administration. The predetermined bioequivalence range for the test drug (capsule) was 80% to 125% of the reference drug (tablet). Drug tolerability was assessed using routine physical examination, including vital-sign measurements; laboratory analysis (hematology, biochemistry, and urinalysis); 12-lead electrocardiography; direct observation; spontaneous reporting; and non specific questioning. This study included 18 subjects (12 men, 6 women; mean [SD] age, 26 [7] years). The mean height and body weight of the subjects were 176 (8) cm and 70.1 (9.6) kg, respectively. The peak exposure, as measured by mean natural logarithm-transformed C(max) values, was significantly lower with the capsule compared with the tablet (2.7 vs 4.0 ng/mL; P definition of bioequivalence when given after a high-fat meal. All AEs were transient and mild in intensity, with asthenia being the most common event with the capsule and tablet formulations, occurring in 5 (28%) and 8 (44

  10. Expanding subjectivities

    DEFF Research Database (Denmark)

    Lundgaard Andersen, Linda; Soldz, Stephen

    2012-01-01

    A major theme in recent psychoanalytic thinking concerns the use of therapist subjectivity, especially “countertransference,” in understanding patients. This thinking converges with and expands developments in qualitative research regarding the use of researcher subjectivity as a tool to understa...

  11. Dark Matter

    Indian Academy of Sciences (India)

    In Part 11 of this article we learnt that there are compelling evidences from dynamics of spiral galaxies, like our own, that there must be non-luminous matter in them. In this second part we will see that even clusters of galaxies must harbour dark matter. As if this was not enough, it turns out that if our knowledge of the ...

  12. Describing Matter

    Science.gov (United States)

    Adams, Krista; Feagin, Shannon

    2017-01-01

    This article presents a lesson that was designed to explore the scientific descriptions of matter through both the intensive and extensive properties that students successfully added to their vocabulary. Students' examples demonstrated that there were places where their reasoning about matter faltered as related to how the material is the same…

  13. Condensed matter physics

    CERN Document Server

    Isihara, A

    2007-01-01

    More than a graduate text and advanced research guide on condensed matter physics, this volume is useful to plasma physicists and polymer chemists, and their students. It emphasizes applications of statistical mechanics to a variety of systems in condensed matter physics rather than theoretical derivations of the principles of statistical mechanics and techniques. Isihara addresses a dozen different subjects in separate chapters, each designed to be directly accessible and used independently of previous chapters. Topics include simple liquids, electron systems and correlations, two-dimensional

  14. Kaluza-Klein dark matter

    CERN Document Server

    Cheng, H C; Matchev, K T; Cheng, Hsin-Chia; Feng, Jonathan L; Matchev, Konstantin T.

    2002-01-01

    We propose that cold dark matter is made of Kaluza-Klein particles and explore avenues for its detection. The lightest Kaluza-Klein state is an excellent dark matter candidate if standard model particles propagate in extra dimensions and Kaluza-Klein parity is conserved. We consider Kaluza-Klein gauge bosons. In sharp contrast to the case of supersymmetric dark matter, these annihilate to hard positrons, neutrinos and photons with unsuppressed rates. Direct detection signals are also promising. These conclusions are generic to bosonic dark matter candidates.

  15. Dark matter search in CMS

    OpenAIRE

    Vartak, Adish

    2017-01-01

    The dark matter search program at the LHC covers a wide range of final states and targets a variety of possible interactions between dark matter and standard model particles. A summary of the dark matter searches performed at the CMS experiment, using proton-proton collision data collected at a center of energy of 13 TeV, is presented.Searches performed in various final states are described, and results interpreted in terms of several dark matter models are presented. These results are also c...

  16. Subject (of documents)

    DEFF Research Database (Denmark)

    Hjørland, Birger

    2017-01-01

    such as concepts, aboutness, topic, isness and ofness are also briefly presented. The conclusion is that the most fruitful way of defining “subject” (of a document) is the documents informative or epistemological potentials, that is, the documents potentials of informing users and advance the development......This article presents and discuss the concept “subject” or subject matter (of documents) as it has been examined in library and information science (LIS) for more than 100 years. Different theoretical positions are outlined and it is found that the most important distinction is between document......-oriented views versus request-oriented views. The document-oriented view conceive subject as something inherent in documents, whereas the request-oriented view (or the policy based view) understand subject as an attribution made to documents in order to facilitate certain uses of them. Related concepts...

  17. Quantitative planar and volumetric cardiac measurements using 64 MDCT and 3T MRI versus standard 2D and M-mode echocardiography: Does anesthetic protocol matter?

    Science.gov (United States)

    Drees, Randi; Johnson, Rebecca A; Stepien, Rebecca L; Rio, Alejandro Munoz Del; Saunders, Jimmy H; François, Christopher J

    2016-01-01

    Cross-sectional imaging of the heart utilizing computed tomography (CT) and magnetic resonance imaging (MRI) has been shown to be superior for the evaluation of cardiac morphology and systolic function in humans compared to echocardiography. The purpose of this prospective study was to test the effects of two different anesthetic protocols on cardiac measurements in 10 healthy beagle dogs using 64-multidetector row computed tomographic angiography (64-MDCTA), 3T magnetic resonance (MRI) and standard awake echocardiography. Both anesthetic protocols used propofol for induction and isoflourane for anesthetic maintenance. In addition, protocol A used midazolam/fentanyl and protocol B used dexmedetomedine as premedication and constant rate infusion during the procedure. Significant elevations in systolic and mean blood pressure were present when using protocol B. There was overall good agreement between the variables of cardiac size and systolic function generated from the MDCTA and MRI exams and no significant difference was found when comparing the variables acquired using either anesthetic protocol within each modality. Systolic function variables generated using 64-MDCTA and 3T MRI were only able to predict the left ventricular end diastolic volume as measured during awake echocardiogram when using protocol B and 64-MDCTA. For all other systolic function variables, prediction of awake echocardiographic results was not possible (P = 1). Planar variables acquired using MDCTA or MRI did not allow prediction of the corresponding measurements generated using echocardiography in the awake patients (P=1). Future studies are needed to validate this approach in a more varied population and clinically affected dogs. PMID:26082285

  18. (Terminology standardization)

    Energy Technology Data Exchange (ETDEWEB)

    Strehlow, R.A.

    1990-10-19

    Terminological requirements in information management was but one of the principal themes of the 2nd Congress on Terminology and Knowledge Engineering. The traveler represented the American Society for Testing and Materials' Committee on Terminology, of which he is the Chair. The traveler's invited workshop emphasized terminology standardization requirements in databases of material properties as well as practical terminology standardizing methods. The congress included six workshops in addition to approximately 82 lectures and papers from terminologists, artificial intelligence practitioners, and subject specialists from 18 countries. There were approximately 292 registrants from 33 countries who participated in the congress. The congress topics were broad. Examples were the increasing use of International Standards Organization (ISO) Standards in legislated systems such as the USSR Automated Data Bank of Standardized Terminology, the enhanced Physics Training Program based on terminology standardization in Physics in the Chinese province of Inner Mongolia, and the technical concept dictionary being developed at the Japan Electronic Dictionary Research Institute, which is considered to be the key to advanced artificial intelligence applications. The more usual roles of terminology work in the areas of machine translation. indexing protocols, knowledge theory, and data transfer in several subject specialties were also addressed, along with numerous special language terminology areas.

  19. Gaseous Matter

    CERN Document Server

    Angelo, Joseph A

    2011-01-01

    aseous Matter focuses on the many important discoveries that led to the scientific interpretation of matter in the gaseous state. This new, full-color resource describes the basic characteristics and properties of several important gases, including air, hydrogen, helium, oxygen, and nitrogen. The nature and scope of the science of fluids is discussed in great detail, highlighting the most important scientific principles upon which the field is based. Chapters include:. Gaseous Matter An Initial Perspective. Physical Characteristics of Gases. The Rise of the Science of Gases. Kinetic Theory of

  20. The Relationship between Dry Matter Increase of Seed and Shoot during the Seed-Filling Period in Three Kinds of Soybeans with Different Growth Habits Subjected to Shading and Thinning

    National Research Council Canada - National Science Library

    Kakiuchi, Jin; Kobata, Tohru

    2006-01-01

    The ratio of dry-matter increase in seed (S) to that in shoot (W), referred to as RS/W, during the seed-filling period may reflect the balance between the assimilate supply and the sink capacity of harvest organs...

  1. Dirac matter

    CERN Document Server

    Rivasseau, Vincent; Fuchs, Jean-Nöel

    2017-01-01

    This fifteenth volume of the Poincare Seminar Series, Dirac Matter, describes the surprising resurgence, as a low-energy effective theory of conducting electrons in many condensed matter systems, including graphene and topological insulators, of the famous equation originally invented by P.A.M. Dirac for relativistic quantum mechanics. In five highly pedagogical articles, as befits their origin in lectures to a broad scientific audience, this book explains why Dirac matters. Highlights include the detailed "Graphene and Relativistic Quantum Physics", written by the experimental pioneer, Philip Kim, and devoted to graphene, a form of carbon crystallized in a two-dimensional hexagonal lattice, from its discovery in 2004-2005 by the future Nobel prize winners Kostya Novoselov and Andre Geim to the so-called relativistic quantum Hall effect; the review entitled "Dirac Fermions in Condensed Matter and Beyond", written by two prominent theoreticians, Mark Goerbig and Gilles Montambaux, who consider many other mater...

  2. Antimatter Matters

    CERN Multimedia

    CERN

    2016-01-01

    This video is a teaser-introduction to the Antimatter Matters exhibtion at the Royal Society's Summer Science exhibition July 4-10 2016. The exhibition is jointly organised and hosted by UK members of the ALPHA and LHCb collaborations.

  3. Exploring the mirror matter interpretation of the DAMA experiment: Has the dark matter problem been solved?

    OpenAIRE

    Foot, R.

    2004-01-01

    The self consistency between the impressive DAMA annual modulation signal and the differential energy spectrum is an important test for dark matter candidates.Mirror matter-type dark matter passes this test while other dark matter candidates, including standard (spin-independent) WIMPs and mini-electric charged particle dark matter, do not do so well.We argue that the unique properties of mirror matter-type dark matter seem to be just those required to fully explain the data, suggesting that ...

  4. WISPy cold dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Arias, Paola [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Pontificia Univ. Catolica de Chile, Santiago (Chile). Facultad de Fisica; Cadamuro, Davide; Redondo, Javier [Max-Planck-Institut fuer Physik, Muenchen (Germany); Goodsell, Mark [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); European Organization for Nuclear Research (CERN), Geneva (Switzerland); Jaeckel, Joerg [Durham Univ. (United Kingdom). Inst. for Particle Physics Phenomenology; Ringwald, Andreas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2012-01-15

    Very weakly interacting slim particles (WISPs), such as axion-like particles (ALPs) or hidden photons (HPs), may be non-thermally produced via the misalignment mechanism in the early universe and survive as a cold dark matter population until today. We find that, both for ALPs and HPs whose dominant interactions with the standard model arise from couplings to photons, a huge region in the parameter spaces spanned by photon coupling and ALP or HP mass can give rise to the observed cold dark matter. Remarkably, a large region of this parameter space coincides with that predicted in well motivated models of fundamental physics. A wide range of experimental searches - exploiting haloscopes (direct dark matter searches exploiting microwave cavities), helioscopes (searches for solar ALPs or HPs), or light-shining-through-a-wall techniques - can probe large parts of this parameter space in the foreseeable future. (orig.)

  5. Dark matter from unification

    DEFF Research Database (Denmark)

    Kainulainen, Kimmo; Tuominen, Kimmo; Virkajärvi, Jussi Tuomas

    2013-01-01

    We consider a minimal extension of the Standard Model (SM), which leads to unification of the SM coupling constants, breaks electroweak symmetry dynamically by a new strongly coupled sector and leads to novel dark matter candidates. In this model, the coupling constant unification requires...... eigenstates of this sector and determine the resulting relic density. The results are constrained by available data from colliders and direct and indirect dark matter experiments. We find the model viable and outline briefly future research directions....... the existence of electroweak triplet and doublet fermions singlet under QCD and new strong dynamics underlying the Higgs sector. Among these new matter fields and a new right handed neutrino, we consider the mass and mixing patterns of the neutral states. We argue for a symmetry stabilizing the lightest mass...

  6. WISPy Cold Dark Matter

    CERN Document Server

    Arias, Paola; Goodsell, Mark; Jaeckel, Joerg; Redondo, Javier; Ringwald, Andreas

    2012-01-01

    Very weakly interacting slim particles (WISPs), such as axion-like particles (ALPs) or hidden photons (HPs), may be non-thermally produced via the misalignment mechanism in the early universe and survive as a cold dark matter population until today. We find that, both for ALPs and HPs whose dominant interactions with the standard model arise from couplings to photons, a huge region in the parameter spaces spanned by photon coupling and ALP or HP mass can give rise to the observed cold dark matter. Remarkably, a large region of this parameter space coincides with that predicted in well motivated models of fundamental physics. A wide range of experimental searches -- exploiting haloscopes (direct dark matter searches exploiting microwave cavities), helioscopes (searches for solar ALPs or HPs), or light-shining-through-a-wall techniques -- can probe large parts of this parameter space in the foreseeable future.

  7. Matter and memory

    CERN Document Server

    Bergson, Henri

    1991-01-01

    Since the end of the last century," Walter Benjamin wrote, "philosophy has made a series of attempts to lay hold of the 'true' experience as opposed to the kind that manifests itself in the standardized, denatured life of the civilized masses. It is customary to classify these efforts under the heading of a philosophy of life. Towering above this literature is Henri Bergson's early monumental work, Matter and Memory."Along with Husserl's Ideas and Heidegger's Being and Time, Bergson's work represents one of the great twentieth-century investigations into perception and memory, movement and time, matter and mind. Arguably Bergson's most significant book, Matter and Memory is essential to an understanding of his philosophy and its legacy.This new edition includes an annotated bibliography prepared by Bruno Paradis.Henri Bergson (1859-1941) was awarded the Nobel Prize in 1927. His works include Time and Free Will, An Introduction to Metaphysics, Creative Evolution, and The Creative Mind.

  8. Dark matter searches

    Science.gov (United States)

    Bettini, Alessandro

    These lectures begin with a brief survey of the astrophysical and cosmological evidence for dark matter. We then consider the three principal theoretically motivated types of dark matter, sterile neutrinos, axions and SUSY WIMPs. In chapter 4 we discuss the motivations for the so-called neutrino minimal standard model, nuMSM, an extension of the SM with three sterile neutrinos with masses similar to the charged fermions. In chapter 5 we briefly recall the strong CP problem of the SM and the solution proposed by Peccei and Quinn leading to the prediction of axions and of their characteristics. We then discuss the experimental status and perspectives. In chapter 6 we assume that the reader to be acquainted with the theoretical motivations for SUSY and move directly to the direct search for dark matter and the description of the principal detector techniques: scintillators, noble fluids and bolometers. We conclude with an outlook on the future perspectives.

  9. SUBJECT INDEX

    Indian Academy of Sciences (India)

    Subject Index. Variation of surface electric field during geomagnetic disturbed period at Maitri, Antarctica. 1721. Geomorphology. A simple depression-filling method for raster and irregular elevation datasets. 1653. Decision Support System integrated with Geographic. Information System to target restoration actions in water-.

  10. A voxel-based morphometric magnetic resonance imaging study of the brain detects age-related gray matter volume changes in healthy subjects of 21–45 years old

    OpenAIRE

    Bourisly, Ali K; El-Beltagi, Ahmed; Cherian, Jigi; Gejo, Grace; Al-Jazzaf, Abrar; Ismail, Mohammad

    2015-01-01

    Previous and more recent work of analyzing structural changes in the brain suggest that certain brain regions such as the frontal lobe are among the brain regions profoundly affected by the aging process across males and females. Also, a unified model of structural changes in a normally aging brain is still lacking. The present study investigated age-related structural brain changes in gray matter from young to early middle-age adulthood for males and females. Magnetic resonance images of 215...

  11. Asymmetric condensed dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Aguirre, Anthony; Diez-Tejedor, Alberto, E-mail: aguirre@scipp.ucsc.edu, E-mail: alberto.diez@fisica.ugto.mx [Santa Cruz Institute for Particle Physics and Department of Physics, University of California, Santa Cruz, CA, 95064 (United States)

    2016-04-01

    We explore the viability of a boson dark matter candidate with an asymmetry between the number densities of particles and antiparticles. A simple thermal field theory analysis confirms that, under certain general conditions, this component would develop a Bose-Einstein condensate in the early universe that, for appropriate model parameters, could survive the ensuing cosmological evolution until now. The condensation of a dark matter component in equilibrium with the thermal plasma is a relativistic process, hence the amount of matter dictated by the charge asymmetry is complemented by a hot relic density frozen out at the time of decoupling. Contrary to the case of ordinary WIMPs, dark matter particles in a condensate must be lighter than a few tens of eV so that the density from thermal relics is not too large. Big-Bang nucleosynthesis constrains the temperature of decoupling to the scale of the QCD phase transition or above. This requires large dark matter-to-photon ratios and very weak interactions with standard model particles.

  12. 7 CFR 29.6015 - Foreign matter.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Foreign matter. 29.6015 Section 29.6015 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... INSPECTION Standards Definitions § 29.6015 Foreign matter. Any extraneous substance or material such as...

  13. Exposures to fine particulate matter (PM2.5) and ozone above USA standards are associated with auditory brainstem dysmorphology and abnormal auditory brainstem evoked potentials in healthy young dogs.

    Science.gov (United States)

    Calderón-Garcidueñas, Lilian; González-González, Luis O; Kulesza, Randy J; Fech, Tatiana M; Pérez-Guillé, Gabriela; Luna, Miguel Angel Jiménez-Bravo; Soriano-Rosales, Rosa Eugenia; Solorio, Edelmira; Miramontes-Higuera, José de Jesús; Gómez-Maqueo Chew, Aline; Bernal-Morúa, Alexia F; Mukherjee, Partha S; Torres-Jardón, Ricardo; Mills, Paul C; Wilson, Wayne J; Pérez-Guillé, Beatriz; D'Angiulli, Amedeo

    2017-10-01

    Delayed central conduction times in the auditory brainstem have been observed in Mexico City (MC) healthy children exposed to fine particulate matter (PM 2.5 ) and ozone (O 3 ) above the current United States Environmental Protection Agency (US-EPA) standards. MC children have α synuclein brainstem accumulation and medial superior olivary complex (MSO) dysmorphology. The present study used a dog model to investigate the potential effects of air pollution on the function and morphology of the auditory brainstem. Twenty-four dogs living in clean air v MC, average age 37.1 ± 26.3 months, underwent brainstem auditory evoked potential (BAEP) measurements. Eight dogs (4 MC, 4 Controls) were analysed for auditory brainstem morphology and histopathology. MC dogs showed ventral cochlear nuclei hypotrophy and MSO dysmorphology with a significant decrease in cell body size, decreased neuronal packing density with regions in the nucleus devoid of neurons and marked gliosis. MC dogs showed significant delayed BAEP absolute wave I, III and V latencies compared to controls. MC dogs show auditory nuclei dysmorphology and BAEPs consistent with an alteration of the generator sites of the auditory brainstem response waveform. This study puts forward the usefulness of BAEPs to study auditory brainstem neurodegenerative changes associated with air pollution in dogs. Recognition of the role of non-invasive BAEPs in urban dogs is warranted to elucidate novel neurodegenerative pathways link to air pollution and a promising early diagnostic strategy for Alzheimer's Disease. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Children's Differentiation between Beliefs about Matters of Fact and Matters of Opinion

    Science.gov (United States)

    Banerjee, Robin; Yuill, Nicola; Larson, Christina; Easton, Kate; Robinson, Elizabeth; Rowley, Martin

    2007-01-01

    Two experiments investigated children's implicit and explicit differentiation between beliefs about matters of fact and matters of opinion. In Experiment 1, 8- to 9-year-olds' (n = 88) explicit understanding of the subjectivity of opinions was found to be limited, but their conformity to others' judgments on a matter of opinion was considerably…

  15. Short-term test-retest-reliability of conditioned pain modulation using the cold-heat-pain method in healthy subjects and its correlation to parameters of standardized quantitative sensory testing.

    Science.gov (United States)

    Gehling, Julia; Mainka, Tina; Vollert, Jan; Pogatzki-Zahn, Esther M; Maier, Christoph; Enax-Krumova, Elena K

    2016-08-05

    Conditioned Pain Modulation (CPM) is often used to assess human descending pain inhibition. Nine different studies on the test-retest-reliability of different CPM paradigms have been published, but none of them has investigated the commonly used heat-cold-pain method. The results vary widely and therefore, reliability measures cannot be extrapolated from one CPM paradigm to another. Aim of the present study was to analyse the test-retest-reliability of the common heat-cold-pain method and its correlation to pain thresholds. We tested the short-term test-retest-reliability within 40 ± 19.9 h using a cold-water immersion (10 °C, left hand) as conditioning stimulus (CS) and heat pain (43-49 °C, pain intensity 60 ± 5 on the 101-point numeric rating scale, right forearm) as test stimulus (TS) in 25 healthy right-handed subjects (12females, 31.6 ± 14.1 years). The TS was applied 30s before (TSbefore), during (TSduring) and after (TSafter) the 60s CS. The difference between the pain ratings for TSbefore and TSduring represents the early CPM-effect, between TSbefore and TSafter the late CPM-effect. Quantitative sensory testing (QST, DFNS protocol) was performed on both sessions before the CPM assessment. paired t-tests, Intraclass correlation coefficient (ICC), standard error of measurement (SEM), smallest real difference (SRD), Pearson's correlation, Bland-Altman analysis, significance level p test-retest-reliability of the early CPM-effect using the heat-cold-pain method in healthy subjects achieved satisfying results in terms of the ICC. The SRD of the early CPM effect showed that an individual change of > 20 NRS can be attributed to a real change rather than chance. The late CPM-effect was weaker and not reliable.

  16. Unified origin for baryonic visible matter and antibaryonic dark matter.

    Science.gov (United States)

    Davoudiasl, Hooman; Morrissey, David E; Sigurdson, Kris; Tulin, Sean

    2010-11-19

    We present a novel mechanism for generating both the baryon and dark matter densities of the Universe. A new Dirac fermion X carrying a conserved baryon number charge couples to the standard model quarks as well as a GeV-scale hidden sector. CP-violating decays of X, produced nonthermally in low-temperature reheating, sequester antibaryon number in the hidden sector, thereby leaving a baryon excess in the visible sector. The antibaryonic hidden states are stable dark matter. A spectacular signature of this mechanism is the baryon-destroying inelastic scattering of dark matter that can annihilate baryons at appreciable rates relevant for nucleon decay searches.

  17. Bootstrapping white matter segmentation, Eve++

    Science.gov (United States)

    Plassard, Andrew; Hinton, Kendra E.; Venkatraman, Vijay; Gonzalez, Christopher; Resnick, Susan M.; Landman, Bennett A.

    2015-03-01

    Multi-atlas labeling has come in wide spread use for whole brain labeling on magnetic resonance imaging. Recent challenges have shown that leading techniques are near (or at) human expert reproducibility for cortical gray matter labels. However, these approaches tend to treat white matter as essentially homogeneous (as white matter exhibits isointense signal on structural MRI). The state-of-the-art for white matter atlas is the single-subject Johns Hopkins Eve atlas. Numerous approaches have attempted to use tractography and/or orientation information to identify homologous white matter structures across subjects. Despite success with large tracts, these approaches have been plagued by difficulties in with subtle differences in course, low signal to noise, and complex structural relationships for smaller tracts. Here, we investigate use of atlas-based labeling to propagate the Eve atlas to unlabeled datasets. We evaluate single atlas labeling and multi-atlas labeling using synthetic atlases derived from the single manually labeled atlas. On 5 representative tracts for 10 subjects, we demonstrate that (1) single atlas labeling generally provides segmentations within 2mm mean surface distance, (2) morphologically constraining DTI labels within structural MRI white matter reduces variability, and (3) multi-atlas labeling did not improve accuracy. These efforts present a preliminary indication that single atlas labels with correction is reasonable, but caution should be applied. To purse multi-atlas labeling and more fully characterize overall performance, more labeled datasets would be necessary.

  18. Dark Matter

    Indian Academy of Sciences (India)

    The study of gas clouds orbiting in the outer regions of spiral galaxies has revealed that their gravitational at- traction is much larger than the stars alone can provide. Over the last twenty years, astronomers have been forced to postulate the presence of large quantities of 'dark matter' to explain their observations. They are ...

  19. Molecule Matters

    Indian Academy of Sciences (India)

    Fluorescence usually originates from the lowest excited electronic state (singlet) irrespective of the excitation and hence, the fluorescence spectrum of a molecule is characterized by a single band. However, what makes DMABN a very special molecule is that it exhibits dual fluorescence (i.e. emission of. Molecule Matters.

  20. Molecule Matters

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 14; Issue 4. Molecule Matters – van der Waals Molecules - History and Some Perspectives on Intermolecular Forces. E Arunan. Feature Article Volume 14 Issue 4 April 2009 pp 346-356 ...

  1. Molecule Matters

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 11; Issue 9. Molecule Matters - A Chromium Compound with a Quintuple Bond. K C Kumara Swamy. Feature Article Volume 11 Issue 9 September 2006 pp 72-75. Fulltext. Click here to view fulltext PDF. Permanent link:

  2. Science Matters

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 2. Science Matters A Book for Curious Minds. Rohini Godbole. Book Review Volume 2 Issue 2 February 1997 pp 94-95. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/002/02/0094-0095 ...

  3. Molecule Matters

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 13; Issue 5. Molecule Matters - N-Heterocyclic Carbenes - The Stable Form of R2 C: Anil J Elias. Feature Article Volume 13 Issue 5 May 2008 pp 456-467. Fulltext. Click here to view fulltext PDF. Permanent link:

  4. Molecule Matters

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 11; Issue 11. Molecule Matters - Carbon Dioxide: Molecular States and Beyond. T P Radhakrishnan. Feature Article Volume 11 Issue 11 November 2006 pp 88-92. Fulltext. Click here to view fulltext PDF. Permanent link:

  5. A History of Dark Matter

    Energy Technology Data Exchange (ETDEWEB)

    Bertone, Gianfranco [U. Amsterdam, GRAPPA; Hooper, Dan [Fermilab

    2016-05-16

    Although dark matter is a central element of modern cosmology, the history of how it became accepted as part of the dominant paradigm is often ignored or condensed into a brief anecdotical account focused around the work of a few pioneering scientists. The aim of this review is to provide the reader with a broader historical perspective on the observational discoveries and the theoretical arguments that led the scientific community to adopt dark matter as an essential part of the standard cosmological model.

  6. Constraining Dark Matter with ATLAS

    CERN Document Server

    Czodrowski, Patrick; The ATLAS collaboration

    2017-01-01

    The presence of a non-baryonic dark matter component in the Universe is inferred from the observation of its gravitational interaction. If dark matter interacts weakly with the Standard Model it would be produced at the LHC, escaping the detector and leaving a large missing transverse momentum as their signature. The ATLAS detector has developed a broad and systematic search program for dark matter production in LHC collisions. The results of these searches on the first 13 TeV data, their interpretation, and the design and possible evolution of the search program will be presented.

  7. A randomized, double-blind, placebo-, and positive-controlled clinical pilot study to evaluate the efficacy and tolerability of standardized aqueous extracts of Terminalia chebula and Terminalia bellerica in subjects with hyperuricemia

    Directory of Open Access Journals (Sweden)

    Usharani P

    2016-06-01

    Full Text Available Pingali Usharani,1 Chandrasekhar Nutalapati,1 Venkata Kishan Pokuri,1 Chiranjeevi Uday Kumar,1 Gangadhar Taduri,21Department of Clinical Pharmacology and Therapeutics, 2Department of Nephrology, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad, India Objectives: To evaluate the efficacy and tolerability of standardized aqueous extracts of Terminalia chebula and Terminalia bellerica versus febuxostat and placebo on reduction in serum uric acid levels in subjects with hyperuricemia. Materials and methods: A total of 110 eligible subjects with hyperuricemia were enrolled and randomized to either of the five treatment groups – T. chebula 500 mg twice a day (BID, T. bellerica 250 mg BID, T. bellerica 500 mg BID, placebo BID, and febuxostat 40 mg once daily plus an identical placebo – for a duration of 24 weeks. Serum uric acid levels were measured at baseline and at the end of 4, 8, 12, 16, 20, and 24 weeks. Statistical analysis was done using GraphPad Prism Software 4. Results and interpretation: All active treatment groups showed a reduction in serum uric acid levels compared to baseline and placebo. Significant reduction in mean serum uric acid levels started as early as 4 weeks following treatment, compared to baseline, with T. bellerica (500 and 250 mg, febuxostat (P<0.001, and T. chebula 500 mg (P<0.01; an increase in serum uric acid levels was seen with placebo (P<0.05. The serum uric acid levels became steady after 16 weeks of treatment and remained the same until the end of 24 weeks. The reduction of serum uric acid levels in the T. bellerica 500 mg group was nearly twice that of the T. chebula 500 mg group as well as T. bellerica 250 mg group at all time points. T. bellerica 500 mg reduced serum uric acid levels from 8.07±0.87 to 5.78±0.25 compared to febuxostat, which reduced serum uric acid levels from 8.53±0.97 to 4.28±0.67 (P<0.001 at the end of 24 weeks. The efficacy of T. bellerica appeared to be dose dependent

  8. New Federal Air Quality Standards.

    Science.gov (United States)

    Stopinski, O. W.

    The report discusses the current procedures for establishing air quality standards, the bases for standards, and, finally, proposed and final National Primary and Secondary Ambient Air Quality Standards for sulfur dioxide, particulate matter, carbon monoxide, nonmethane hydrocarbons, photochemical oxidants, and nitrogen dioxide. (Author/RH)

  9. Gray matter and white matter abnormalities in online game addiction

    Energy Technology Data Exchange (ETDEWEB)

    Weng, Chuan-Bo, E-mail: send007@163.com [Department of Neurosurgery, Anhui Provincial Hospital Affiliated to Anhui Medical University, 17 Lujiang Road, Hefei, Ahui Province 230001 (China); School of Neurosurgery, Anhui Medical University, 81 Meishang Road, Hefei, Anhui Province 230032 (China); Qian, Ruo-Bing, E-mail: rehomail@163.com [Department of Neurosurgery, Anhui Provincial Hospital Affiliated to Anhui Medical University, 17 Lujiang Road, Hefei, Ahui Province 230001 (China); Anhui Provincial Institute of Stereotactic Neurosurgery, 9 Lujiang Road, Hefei, Ahui Province 230001 (China); Fu, Xian-Ming, E-mail: 506537677@qq.com [Department of Neurosurgery, Anhui Provincial Hospital Affiliated to Anhui Medical University, 17 Lujiang Road, Hefei, Ahui Province 230001 (China); Anhui Provincial Institute of Stereotactic Neurosurgery, 9 Lujiang Road, Hefei, Ahui Province 230001 (China); Lin, Bin, E-mail: 274722758@qq.com [School of Neurosurgery, Anhui Medical University, 81 Meishang Road, Hefei, Anhui Province 230032 (China); Han, Xiao-Peng, E-mail: hanxiaopeng@163.com [Department of Psychology, Anhui Provincial Hospital Affiliated to Anhui Medical University, 17 Lujiang Road, Hefei, Ahui Province 230001 (China); Niu, Chao-Shi, E-mail: niuchaoshi@163.com [Department of Neurosurgery, Anhui Provincial Hospital Affiliated to Anhui Medical University, 17 Lujiang Road, Hefei, Ahui Province 230001 (China); Anhui Provincial Institute of Stereotactic Neurosurgery, 9 Lujiang Road, Hefei, Ahui Province 230001 (China); Wang, Ye-Han, E-mail: wangyehan@163.com [Department of Neurosurgery, Anhui Provincial Hospital Affiliated to Anhui Medical University, 17 Lujiang Road, Hefei, Ahui Province 230001 (China); Anhui Provincial Institute of Stereotactic Neurosurgery, 9 Lujiang Road, Hefei, Ahui Province 230001 (China)

    2013-08-15

    Online game addiction (OGA) has attracted greater attention as a serious public mental health issue. However, there are only a few brain magnetic resonance imaging studies on brain structure about OGA. In the current study, we used voxel-based morphometry (VBM) analysis and tract-based spatial statistics (TBSS) to investigate the microstructural changes in OGA and assessed the relationship between these morphology changes and the Young's Internet Addiction Scale (YIAS) scores within the OGA group. Compared with healthy subjects, OGA individuals showed significant gray matter atrophy in the right orbitofrontal cortex, bilateral insula, and right supplementary motor area. According to TBSS analysis, OGA subjects had significantly reduced FA in the right genu of corpus callosum, bilateral frontal lobe white matter, and right external capsule. Gray matter volumes (GMV) of the right orbitofrontal cortex, bilateral insula and FA values of the right external capsule were significantly positively correlated with the YIAS scores in the OGA subjects. Our findings suggested that microstructure abnormalities of gray and white matter were present in OGA subjects. This finding may provide more insights into the understanding of the underlying neural mechanisms of OGA.

  10. Gray matter and white matter abnormalities in online game addiction.

    Science.gov (United States)

    Weng, Chuan-Bo; Qian, Ruo-Bing; Fu, Xian-Ming; Lin, Bin; Han, Xiao-Peng; Niu, Chao-Shi; Wang, Ye-Han

    2013-08-01

    Online game addiction (OGA) has attracted greater attention as a serious public mental health issue. However, there are only a few brain magnetic resonance imaging studies on brain structure about OGA. In the current study, we used voxel-based morphometry (VBM) analysis and tract-based spatial statistics (TBSS) to investigate the microstructural changes in OGA and assessed the relationship between these morphology changes and the Young's Internet Addiction Scale (YIAS) scores within the OGA group. Compared with healthy subjects, OGA individuals showed significant gray matter atrophy in the right orbitofrontal cortex, bilateral insula, and right supplementary motor area. According to TBSS analysis, OGA subjects had significantly reduced FA in the right genu of corpus callosum, bilateral frontal lobe white matter, and right external capsule. Gray matter volumes (GMV) of the right orbitofrontal cortex, bilateral insula and FA values of the right external capsule were significantly positively correlated with the YIAS scores in the OGA subjects. Our findings suggested that microstructure abnormalities of gray and white matter were present in OGA subjects. This finding may provide more insights into the understanding of the underlying neural mechanisms of OGA. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  11. Thermal Dark Matter Below a MeV

    OpenAIRE

    Berlin, Asher; Blinov, Nikita

    2018-01-01

    We consider a class of models in which thermal dark matter is lighter than a MeV. If dark matter thermalizes with the standard model below the temperature of neutrino-photon decoupling, equilibration and freeze-out cool and heat the standard model bath comparably, alleviating constraints from measurements of the effective number of neutrino species. We demonstrate this mechanism in a model consisting of fermionic dark matter coupled to a light scalar mediator. Thermal dark matter can be as li...

  12. Self-Destructing Dark Matter

    Energy Technology Data Exchange (ETDEWEB)

    Grossman, Yuval [Cornell U., LEPP; Harnik, Roni [Fermilab; Telem, Ofri [Cornell U., LEPP; Zhang, Yue [Northwestern U.

    2017-12-01

    We present Self-Destructing Dark Matter (SDDM), a new class of dark matter models which are detectable in large neutrino detectors. In this class of models, a component of dark matter can transition from a long-lived state to a short-lived one by scattering off of a nucleus or an electron in the Earth. The short-lived state then decays to Standard Model particles, generating a dark matter signal with a visible energy of order the dark matter mass rather than just its recoil. This leads to striking signals in large detectors with high energy thresholds. We present a few examples of models which exhibit self destruction, all inspired by bound state dynamics in the Standard Model. The models under consideration exhibit a rich phenomenology, possibly featuring events with one, two, or even three lepton pairs, each with a fixed invariant mass and a fixed energy, as well as non-trivial directional distributions. This motivates dedicated searches for dark matter in large underground detectors such as Super-K, Borexino, SNO+, and DUNE.

  13. Mixed Inert scalar triplet dark matter, radiative neutrino masses and leptogenesis

    Directory of Open Access Journals (Sweden)

    Wen-Bin Lu

    2017-11-01

    Full Text Available The neutral component of an inert scalar multiplet with hypercharge can provide a stable dark matter particle when its real and imaginary parts have a splitting mass spectrum. Otherwise, a tree-level dark-matter-nucleon scattering mediated by the Z boson will be much above the experimental limit. In this paper we focus on a mixed inert scalar triplet dark matter scenario where a complex scalar triplet with hypercharge can mix with another real scalar triplet without hypercharge through their renormalizable coupling to the standard model Higgs doublet. We consider three specified cases that carry most of the relevant features of the full parameter space: (i the neutral component of the real triplet dominates the dark matter particle, (ii the neutral component of the complex triplet dominates the dark matter particle; and (iii the neutral components of the real and complex triplets equally constitute the dark matter particle. Subject to the dark matter relic abundance and direct detection constraint, we perform a systematic study on the allowed parameter space with particular emphasis on the interplay among triplet-doublet terms and gauge interactions. In the presence of these mixed inert scalar triplets, some heavy Dirac fermions composed of inert fermion doublets can be utilized to generate a tiny Majorana neutrino mass term at one-loop level and realize a successful leptogenesis for explaining the cosmic baryon asymmetry.

  14. The Cosmology of Composite Inelastic Dark Matter

    Energy Technology Data Exchange (ETDEWEB)

    Spier Moreira Alves, Daniele; Behbahani, Siavosh R.; /SLAC /Stanford U., ITP; Schuster, Philip; Wacker, Jay G.; /SLAC

    2011-08-19

    Composite dark matter is a natural setting for implementing inelastic dark matter - the O(100 keV) mass splitting arises from spin-spin interactions of constituent fermions. In models where the constituents are charged under an axial U(1) gauge symmetry that also couples to the Standard Model quarks, dark matter scatters inelastically off Standard Model nuclei and can explain the DAMA/LIBRA annual modulation signal. This article describes the early Universe cosmology of a minimal implementation of a composite inelastic dark matter model where the dark matter is a meson composed of a light and a heavy quark. The synthesis of the constituent quarks into dark hadrons results in several qualitatively different configurations of the resulting dark matter composition depending on the relative mass scales in the system.

  15. Play Matters

    DEFF Research Database (Denmark)

    Sicart (Vila), Miguel Angel

    ? In Play Matters, Miguel Sicart argues that to play is to be in the world; playing is a form of understanding what surrounds us and a way of engaging with others. Play goes beyond games; it is a mode of being human. We play games, but we also play with toys, on playgrounds, with technologies and design......, but not necessarily fun. Play can be dangerous, addictive, and destructive. Along the way, Sicart considers playfulness, the capacity to use play outside the context of play; toys, the materialization of play--instruments but also play pals; playgrounds, play spaces that enable all kinds of play; beauty...

  16. Active matter

    Science.gov (United States)

    Ramaswamy, Sriram

    2017-05-01

    The study of systems with sustained energy uptake and dissipation at the scale of the constituent particles is an area of central interest in nonequilibrium statistical physics. Identifying such systems as a distinct category—Active matter—unifies our understanding of autonomous collective movement in the living world and in some surprising inanimate imitations. In this article I present the active matter framework, briefly recall some early work, review our recent results on single-particle and collective behaviour, including experiments on active granular monolayers, and discuss new directions for the future.

  17. Software Development Standard Processes (SDSP)

    Science.gov (United States)

    Lavin, Milton L.; Wang, James J.; Morillo, Ronald; Mayer, John T.; Jamshidian, Barzia; Shimizu, Kenneth J.; Wilkinson, Belinda M.; Hihn, Jairus M.; Borgen, Rosana B.; Meyer, Kenneth N.; hide

    2011-01-01

    A JPL-created set of standard processes is to be used throughout the lifecycle of software development. These SDSPs cover a range of activities, from management and engineering activities, to assurance and support activities. These processes must be applied to software tasks per a prescribed set of procedures. JPL s Software Quality Improvement Project is currently working at the behest of the JPL Software Process Owner to ensure that all applicable software tasks follow these procedures. The SDSPs are captured as a set of 22 standards in JPL s software process domain. They were developed in-house at JPL by a number of Subject Matter Experts (SMEs) residing primarily within the Engineering and Science Directorate, but also from the Business Operations Directorate and Safety and Mission Success Directorate. These practices include not only currently performed best practices, but also JPL-desired future practices in key thrust areas like software architecting and software reuse analysis. Additionally, these SDSPs conform to many standards and requirements to which JPL projects are beholden.

  18. Standards not that standard.

    Science.gov (United States)

    Vilanova, Cristina; Tanner, Kristie; Dorado-Morales, Pedro; Villaescusa, Paula; Chugani, Divya; Frías, Alba; Segredo, Ernesto; Molero, Xavier; Fritschi, Marco; Morales, Lucas; Ramón, Daniel; Peña, Carlos; Peretó, Juli; Porcar, Manuel

    2015-01-01

    There is a general assent on the key role of standards in Synthetic Biology. In two consecutive letters to this journal, suggestions on the assembly methods for the Registry of standard biological parts have been described. We fully agree with those authors on the need of a more flexible building strategy and we highlight in the present work two major functional challenges standardization efforts have to deal with: the need of both universal and orthogonal behaviors. We provide experimental data that clearly indicate that such engineering requirements should not be taken for granted in Synthetic Biology.

  19. Dark Matter Jets at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Bai, Yang; /SLAC; Rajaraman, Arvind; /UC, Irvine

    2012-03-28

    We argue that dark matter particles which have strong interactions with the Standard Model particles are not excluded by current astrophysical constraints. These dark matter particles have unique signatures at colliders; instead of missing energy, the dark matter particles produce jets. We propose a new search strategy for such strongly interacting particles by looking for a signal of two trackless jets. We show that suitable cuts can plausibly allow us to find these signals at the LHC even in early data.

  20. Dark Matter Annihilation at the Galactic Center

    Energy Technology Data Exchange (ETDEWEB)

    Linden, Timothy Ryan [Univ. of California, Santa Cruz, CA (United States)

    2013-06-01

    Observations by the WMAP and PLANCK satellites have provided extraordinarily accurate observations on the densities of baryonic matter, dark matter, and dark energy in the universe. These observations indicate that our universe is composed of approximately ve times as much dark matter as baryonic matter. However, e orts to detect a particle responsible for the energy density of dark matter have been unsuccessful. Theoretical models have indicated that a leading candidate for the dark matter is the lightest supersymmetric particle, which may be stable due to a conserved R-parity. This dark matter particle would still be capable of interacting with baryons via weak-force interactions in the early universe, a process which was found to naturally explain the observed relic abundance of dark matter today. These residual annihilations can persist, albeit at a much lower rate, in the present universe, providing a detectable signal from dark matter annihilation events which occur throughout the universe. Simulations calculating the distribution of dark matter in our galaxy almost universally predict the galactic center of the Milky Way Galaxy (GC) to provide the brightest signal from dark matter annihilation due to its relative proximity and large simulated dark matter density. Recent advances in telescope technology have allowed for the rst multiwavelength analysis of the GC, with suitable e ective exposure, angular resolution, and energy resolution in order to detect dark matter particles with properties similar to those predicted by the WIMP miracle. In this work, I describe ongoing e orts which have successfully detected an excess in -ray emission from the region immediately surrounding the GC, which is di cult to describe in terms of standard di use emission predicted in the GC region. While the jury is still out on any dark matter interpretation of this excess, I describe several related observations which may indicate a dark matter origin. Finally, I discuss the

  1. Dark Matter, the MCSSM and lattice QCD

    Energy Technology Data Exchange (ETDEWEB)

    Joel Giedt, Anthony Thomas, Ross Young

    2009-11-01

    Recent lattice measurements have given accurate estimates of the quark condensates in the proton. We use these results to significantly improve the dark matter predictions in benchmark models within the constrained minimal supersymmetric standard model. The predicted spin-independent cross sections are at least an order of magnitude smaller than previously suggested and our results have significant consequences for dark matter searches.

  2. Update on scalar singlet dark matter

    NARCIS (Netherlands)

    Cline, J.M.; Scott, P.; Kainulainen, K.; Weniger, C.

    2013-01-01

    One of the simplest models of dark matter is where a scalar singlet field S comprises some or all of the dark matter and interacts with the standard model through an vertical bar H vertical bar S-2(2) coupling to the Higgs boson. We update the present limits on the model from LHC searches for

  3. 7 CFR 29.1020 - Foreign matter.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Foreign matter. 29.1020 Section 29.1020 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 92) § 29.1020 Foreign matter. Any extraneous substance or material such as straw, strings, rubber...

  4. 7 CFR 29.2270 - Foreign matter.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Foreign matter. 29.2270 Section 29.2270 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Foreign matter. Any extraneous substance or material such as stalks, suckers, straw, strings, rubber bands...

  5. 7 CFR 30.21 - Foreign matter.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Foreign matter. 30.21 Section 30.21 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Foreign matter. Any substance or material extraneous to tobacco leaves, such as dirt, sand, stalks...

  6. 7 CFR 29.3023 - Foreign matter.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Foreign matter. 29.3023 Section 29.3023 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Foreign matter. Any extraneous substance or material such as stalks, suckers, straw, strings, rubber bands...

  7. 7 CFR 29.3518 - Foreign matter.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Foreign matter. 29.3518 Section 29.3518 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 95) § 29.3518 Foreign matter. Any extraneous substance or material such as stalks, suckers, straw...

  8. 7 CFR 29.2520 - Foreign matter.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Foreign matter. 29.2520 Section 29.2520 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing...-Cured Tobacco (u.s. Types 22, 23, and Foreign Type 96) § 29.2520 Foreign matter. Any extraneous...

  9. Human endogenous retrovirus K(HML-2) Gag- and Env-specific T-cell responses are infrequently detected in HIV-1-infected subjects using standard peptide matrix-based screening

    NARCIS (Netherlands)

    R.B. Jones (R. Brad); V.M. John (Vivek); D.V. Hunter (Diana); E. Martin (Eric); S. Mujib (Shariq); V. Mihajlovic (Vesna); P.C. Burgers (Peter); T.M. Luider (Theo); G. Gyenes (Gabor); N.C. Sheppard (Neil); D. SenGupta (Devi); R. Tandon (Ravi); F.-Y. Yue (Feng-Yun); W.S. Benko (William); C. Kovacs (Carrie); R. Nixon; M.A. Ostrowski (Mario)

    2012-01-01

    textabstractT-cell responses to human endogenous retrovirus (HERV) K(HML-2) Gag and Env were mapped in HIV-1-infected subjects using 15mer peptides. Small peptide pools and high concentrations were used to maximize sensitivity. In the 23 subjects studied, only three bona fide HERV-K(HML-2)-specific

  10. Mimicking Dark Matter

    OpenAIRE

    Bel, Lluís

    2017-01-01

    I show that a very simple model in the context of Newtonian physics promoted to a first approximation of general relativity can mimic Dark matter and explain most of its intriguing properties. Namely: i) Dark matter is a halo associated to ordinary matter; ii) Dark matter does not interact with ordinary matter nor with itself; iii) Its influence grows with the size of the aggregate of ordinary matter that is considered, and iv) Dark matter influences the propagation of light.

  11. Play Matters

    DEFF Research Database (Denmark)

    Sicart (Vila), Miguel Angel

    What do we think about when we think about play? A pastime? Games? Childish activities? The opposite of work? Think again: If we are happy and well rested, we may approach even our daily tasks in a playful way, taking the attitude of play without the activity of play. So what, then, is play......, but not necessarily fun. Play can be dangerous, addictive, and destructive. Along the way, Sicart considers playfulness, the capacity to use play outside the context of play; toys, the materialization of play--instruments but also play pals; playgrounds, play spaces that enable all kinds of play; beauty......? In Play Matters, Miguel Sicart argues that to play is to be in the world; playing is a form of understanding what surrounds us and a way of engaging with others. Play goes beyond games; it is a mode of being human. We play games, but we also play with toys, on playgrounds, with technologies and design...

  12. Maxwell Matters

    CERN Document Server

    Eisenberg, Bob

    2016-01-01

    Charges are everywhere because most atoms are charged. Chemical bonds are formed by electrons with their charge. Charges move and interact according to Maxwell's equations in space and in atoms where the equations of electrodynamics are embedded in Schroedinger's equation as the potential. Maxwell's equations are universal, valid inside atoms and between stars from times much shorter than those of atomic motion (0.1 femtoseconds) to years (32 mega-seconds). Maxwell's equations enforce the conservation of current. Analysis shows that the electric field can take on whatever value is needed to ensure conservation of current. The properties of matter rearrange themselves to satisfy Maxwell's equations and conservation of current. Conservation of current is as universal as Maxwell's equations themselves. Yet equations of electrodynamics find little place in the literature of material physics, chemistry, or biochemistry. Kinetic models of chemistry and Markov treatments of atomic motion are ordinary differential eq...

  13. Play Matters

    DEFF Research Database (Denmark)

    Sicart (Vila), Miguel Angel

    What do we think about when we think about play? A pastime? Games? Childish activities? The opposite of work? Think again: If we are happy and well rested, we may approach even our daily tasks in a playful way, taking the attitude of play without the activity of play. So what, then, is play......? In Play Matters, Miguel Sicart argues that to play is to be in the world; playing is a form of understanding what surrounds us and a way of engaging with others. Play goes beyond games; it is a mode of being human. We play games, but we also play with toys, on playgrounds, with technologies and design......, but not necessarily fun. Play can be dangerous, addictive, and destructive. Along the way, Sicart considers playfulness, the capacity to use play outside the context of play; toys, the materialization of play--instruments but also play pals; playgrounds, play spaces that enable all kinds of play; beauty...

  14. Halal Matters

    DEFF Research Database (Denmark)

    In today’s globalized world, halal (meaning ‘permissible’ or ‘lawful’) is about more than food. Politics, power and ethics all play a role in the halal industry in setting new standards for production, trade, consumption and regulation. The question of how modern halal markets are constituted...... is increasingly important and complex. Written from a unique interdisciplinary global perspective, this book demonstrates that as the market for halal products and services is expanding and standardizing, it is also fraught with political, social and economic contestation and difference. The discussion...

  15. Supersymmetric Dark Matter Candidates

    CERN Document Server

    Ellis, John

    2010-01-01

    After reviewing the theoretical, phenomenological and experimental motivations for supersymmetric extensions of the Standard Model, we recall that supersymmetric relics from the Big Bang are expected in models that conserve R parity. We then discuss possible supersymmetric dark matter candidates, focusing on the lightest neutralino and the gravitino. In the latter case, the next-to-lightest supersymmetric particle is expected to be long-lived, and possible candidates include spartners of the tau lepton, top quark and neutrino. We then discuss the roles of the renormalization-group equations and electroweak symmetry breaking in delimiting the supersymmetric parameter space. We discuss in particular the constrained minimal extension of the Standard Model (CMSSM), in which the supersymmetry-breaking parameters are assumed to be universal at the grand unification scale, presenting predictions from a frequentist analysis of its parameter space. We also discuss astrophysical and cosmological constraints on gravitin...

  16. Size matter!

    DEFF Research Database (Denmark)

    Hansen, Pelle Guldborg; Jespersen, Andreas Maaløe; Skov, Laurits Rhoden

    2015-01-01

    trash bags according to size of plates and weighed in bulk. Results Those eating from smaller plates (n=145) left significantly less food to waste (aver. 14,8g) than participants eating from standard plates (n=75) (aver. 20g) amounting to a reduction of 25,8%. Conclusions Our field experiment tests...

  17. Radiative accidental matter

    Energy Technology Data Exchange (ETDEWEB)

    Sierra, D. Aristizabal [IFPA, Dép. AGO, Université de Liège,Bât B5, Sart Tilman B-4000 Liège 1 (Belgium); Universidad Técnica Federico Santa María - Departamento de Física,Casilla 110-V, Avda. España 1680, Valparaíso (Chile); Simoes, C.; Wegman, D. [IFPA, Dép. AGO, Université de Liège,Bât B5, Sart Tilman B-4000 Liège 1 (Belgium)

    2016-07-25

    Accidental matter models are scenarios where the beyond-the-standard model physics preserves all the standard model accidental and approximate symmetries up to a cutoff scale related with lepton number violation. We study such scenarios assuming that the new physics plays an active role in neutrino mass generation, and show that this unavoidably leads to radiatively induced neutrino masses. We systematically classify all possible models and determine their viability by studying electroweak precision data, big bang nucleosynthesis and electroweak perturbativity, finding that the latter places the most stringent constraints on the mass spectra. These results allow the identification of minimal radiative accidental matter models for which perturbativity is lost at high scales. We calculate radiative charged-lepton flavor violating processes in these setups, and show that μ→eγ has a rate well within MEG sensitivity provided the lepton-number violating scale is at or below 5×10{sup 5} GeV, a value (naturally) assured by the radiative suppression mechanism. Sizeable τ→μγ branching fractions within SuperKEKB sensitivity are possible for lower lepton-number breaking scales. We thus point out that these scenarios can be tested not only in direct searches but also in lepton flavor-violating experiments.

  18. Interaction of radiation with matter

    CERN Document Server

    Nikjoo, Hooshang; Emfietzoglou, Dimitris

    2012-01-01

    Written for students approaching the subject for the first time, this text provides a solid grounding in the physics of the interactions of photons and particles with matter, which is the basis of radiological physics and radiation dosimetry. The authors first present the relevant atomic physics and then describe the interactions, emphasizing practical applications in health/medical physics and radiation biology. They cover such important topics as microdosimetry, interaction of photons with matter, electron energy loss, and dielectric response. Each chapter includes exercises and a summary.

  19. Multicomponent Dark Matter in Radiative Seesaw Models

    OpenAIRE

    Aoki, Mayumi; Kaneko, Daiki; Kubo, Jisuke

    2017-01-01

    We discuss radiative seesaw models, in which an exact $Z_2\\times Z_2'$ symmetry is imposed. Due to the exact $Z_2\\times Z_2'$ symmetry, neutrino masses are generated at a two-loop level and at least two extra stable electrically neutral particles are predicted. We consider two models: one has a multi-component dark matter system and the other one has a dark radiation in addition to a dark matter. In the multi-component dark matter system, non-standard dark matter annihilation processes exist....

  20. Dark Matter Coannihilation with a Lighter Species

    Science.gov (United States)

    Berlin, Asher

    2017-09-01

    We propose a new thermal freeze-out mechanism for ultraheavy dark matter. Dark matter coannihilates with a lighter unstable species that is nearby in mass, leading to an annihilation rate that is exponentially enhanced relative to standard weakly interactive massive particles. This scenario destabilizes any potential dark matter candidate. In order to remain consistent with astrophysical observations, our proposal necessitates very long-lived states, motivating striking phenomenology associated with the late decays of ultraheavy dark matter, potentially as massive as the scale of grand unified theories, MGUT˜1016 GeV .

  1. Dark Matter Coannihilation with a Lighter Species.

    Science.gov (United States)

    Berlin, Asher

    2017-09-22

    We propose a new thermal freeze-out mechanism for ultraheavy dark matter. Dark matter coannihilates with a lighter unstable species that is nearby in mass, leading to an annihilation rate that is exponentially enhanced relative to standard weakly interactive massive particles. This scenario destabilizes any potential dark matter candidate. In order to remain consistent with astrophysical observations, our proposal necessitates very long-lived states, motivating striking phenomenology associated with the late decays of ultraheavy dark matter, potentially as massive as the scale of grand unified theories, M_{GUT}∼10^{16}  GeV.

  2. Culture Matters

    Directory of Open Access Journals (Sweden)

    Gillian Warner-Søderholm

    2012-12-01

    Full Text Available Whether managers are concerned with financial issues, marketing, or human resource management (HRM, cultural values and practices do matter. The purpose of this article is to understand Norwegian managers’ cultural values within the cross-cultural landscape of her neighbors in the “Scandinavian cluster.” Clearly, subtle but disturbing differences may surface even when representatives from similar cultures work together. As a follow on from the GLOBE project, data based on the GLOBE instrument were collected on culture and communication values in Norway from 710 Norwegian middle managers for this present study. Although the Scandinavian cultures appear ostensibly similar, the results illustrate that research can reveal subtle but important cultural differences in nations that are similar yet dissimilar. All three Scandinavian societies appear intrinsically egalitarian; they appear to value low Power Distance, directness, and consensus in decision making and to promote Gender Egalitarianism. Nevertheless, there are significant differences in the degrees of commitment to these values by each individual Scandinavian partner. These differences need to be understood and appreciated to avoid misunderstandings.

  3. Dark Matter Searches at ATLAS

    CERN Multimedia

    CERN. Geneva

    2016-01-01

    The astrophysical evidence of dark matter provides some of the most compelling clues to the nature of physics beyond the Standard Model. From these clues, ATLAS has developed a broad and systematic search program for dark matter production in LHC collisions. These searches are now entering their prime, with the LHC now colliding protons at the increased 13 TeV centre-of-mass energy and set to deliver much larger datasets than ever before. The results of these searches on the first 13 TeV data, their interpretation, and the design and possible evolution of the search program will be presented.

  4. Correlation between white matter damage and gray matter lesions in multiple sclerosis patients.

    Science.gov (United States)

    Han, Xue-Mei; Tian, Hong-Ji; Han, Zheng; Zhang, Ce; Liu, Ying; Gu, Jie-Bing; Bakshi, Rohit; Cao, Xia

    2017-05-01

    We observed the characteristics of white matter fibers and gray matter in multiple sclerosis patients, to identify changes in diffusion tensor imaging fractional anisotropy values following white matter fiber injury. We analyzed the correlation between fractional anisotropy values and changes in whole-brain gray matter volume. The participants included 20 patients with relapsing-remitting multiple sclerosis and 20 healthy volunteers as controls. All subjects underwent head magnetic resonance imaging and diffusion tensor imaging. Our results revealed that fractional anisotropy values decreased and gray matter volumes were reduced in the genu and splenium of corpus callosum, left anterior thalamic radiation, hippocampus, uncinate fasciculus, right corticospinal tract, bilateral cingulate gyri, and inferior longitudinal fasciculus in multiple sclerosis patients. Gray matter volumes were significantly different between the two groups in the right frontal lobe (superior frontal, middle frontal, precentral, and orbital gyri), right parietal lobe (postcentral and inferior parietal gyri), right temporal lobe (caudate nucleus), right occipital lobe (middle occipital gyrus), right insula, right parahippocampal gyrus, and left cingulate gyrus. The voxel sizes of atrophic gray matter positively correlated with fractional anisotropy values in white matter association fibers in the patient group. These findings suggest that white matter fiber bundles are extensively injured in multiple sclerosis patients. The main areas of gray matter atrophy in multiple sclerosis are the frontal lobe, parietal lobe, caudate nucleus, parahippocampal gyrus, and cingulate gyrus. Gray matter atrophy is strongly associated with white matter injury in multiple sclerosis patients, particularly with injury to association fibers.

  5. Constraining properties of dark matter particles using astrophysical data

    NARCIS (Netherlands)

    Iakubovskyi, Dmytro

    2013-01-01

    A microscopic origin of dark matter phenomenon is the most plausible hypothesis to explain the mystery of dark matter. The dark matter particle hypothesis necessarily implies an extension of the Standard Model. In this thesis, we undertook a systematic model-independent program of studying the

  6. Taming astrophysical bias in direct dark matter searches

    NARCIS (Netherlands)

    Pato, M.; Strigari, L.E.; Trotta, R.; Bertone, G.

    2013-01-01

    We explore systematic biases in the identification of dark matter in future direct detection experiments and compare the reconstructed dark matter properties when assuming a self-consistent dark matter distribution function and the standard Maxwellian velocity distribution. We find that the

  7. 40 CFR 52.2584 - Control strategy; Particulate matter.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Control strategy; Particulate matter... Control strategy; Particulate matter. (a) Part D—Disapproval—USEPA disapproves Regulation NR 154.11(7)(b... control strategy to attain and maintain the standards for particulate matter, because it does not contain...

  8. Simulating Gravity: Dark Matter and Gravitational Lensing in the Classroom

    Science.gov (United States)

    Ford, Jes; Stang, Jared; Anderson, Catherine

    2015-01-01

    Dark matter makes up most of the matter in the universe but very little of a standard introductory physics curriculum. Here we present our construction and use of a spandex sheet-style gravity simulator to qualitatively demonstrate two aspects of modern physics related to dark matter. First, we describe an activity in which students explore the…

  9. Natural Implementation of Neutralino Dark Matter

    CERN Document Server

    King, S F

    2006-01-01

    The prediction of neutralino dark matter is generally regarded as one of the successes of the Minimal Supersymmetric Standard Model (MSSM). However the successful regions of parameter space allowed by WMAP and collider constraints are quite restricted. We discuss fine-tuning with respect to both dark matter and Electroweak Symmetry Breaking (EWSB) and explore regions of MSSM parameter space with non-universal gaugino and third family scalar masses in which neutralino dark matter may be implemented naturally. In particular allowing non-universal gauginos opens up the bulk region that allows Bino annihilation via t-channel slepton exchange, leading to ``supernatural dark matter'' corresponding to no fine-tuning at all with respect to dark matter. By contrast we find that the recently proposed ``well tempered neutralino'' regions involve substantial fine-tuning of MSSM parameters in order to satisfy the dark matter constraints, although the fine tuning may be ameliorated if several annihilation channels act simu...

  10. Tissue-Based MRI Intensity Standardization: Application to Multicentric Datasets

    Directory of Open Access Journals (Sweden)

    Nicolas Robitaille

    2012-01-01

    Full Text Available Intensity standardization in MRI aims at correcting scanner-dependent intensity variations. Existing simple and robust techniques aim at matching the input image histogram onto a standard, while we think that standardization should aim at matching spatially corresponding tissue intensities. In this study, we present a novel automatic technique, called STI for STandardization of Intensities, which not only shares the simplicity and robustness of histogram-matching techniques, but also incorporates tissue spatial intensity information. STI uses joint intensity histograms to determine intensity correspondence in each tissue between the input and standard images. We compared STI to an existing histogram-matching technique on two multicentric datasets, Pilot E-ADNI and ADNI, by measuring the intensity error with respect to the standard image after performing nonlinear registration. The Pilot E-ADNI dataset consisted in 3 subjects each scanned in 7 different sites. The ADNI dataset consisted in 795 subjects scanned in more than 50 different sites. STI was superior to the histogram-matching technique, showing significantly better intensity matching for the brain white matter with respect to the standard image.

  11. Introduction. Cosmology meets condensed matter.

    Science.gov (United States)

    Kibble, T W B; Pickett, G R

    2008-08-28

    At first sight, low-temperature condensed-matter physics and early Universe cosmology seem worlds apart. Yet, in the last few years a remarkable synergy has developed between the two. It has emerged that, in terms of their mathematical description, there are surprisingly close parallels between them. This interplay has been the subject of a very successful European Science Foundation (ESF) programme entitled COSLAB ('Cosmology in the Laboratory') that ran from 2001 to 2006, itself built on an earlier ESF network called TOPDEF ('Topological Defects: Non-equilibrium Field Theory in Particle Physics, Condensed Matter and Cosmology'). The articles presented in this issue of Philosophical Transactions A are based on talks given at the Royal Society Discussion Meeting 'Cosmology meets condensed matter', held on 28 and 29 January 2008. Many of the speakers had participated earlier in the COSLAB programme, but the strength of the field is illustrated by the presence also of quite a few new participants.

  12. Physics Beyond the Standard Model

    CERN Document Server

    Ellis, John

    2009-01-01

    The Standard Model is in good shape, apart possibly from g_\\mu - 2 and some niggling doubts about the electroweak data. Something like a Higgs boson is required to provide particle masses, but theorists are actively considering alternatives. The problems of flavour, unification and quantum gravity will require physics beyond the Standard Model, and astrophysics and cosmology also provide reasons to expect physics beyond the Standard Model, in particular to provide the dark matter and explain the origin of the matter in the Universe. Personally, I find supersymmetry to be the most attractive option for new physics at the TeV scale. The LHC should establish the origin of particle masses has good prospects for discovering dark matter, and might also cast light on unification and even quantum gravity. Important roles may also be played by lower-energy experiments, astrophysics and cosmology in the searches for new physics beyond the Standard Model.

  13. Looks Matter

    DEFF Research Database (Denmark)

    Kjærgaard, Rikke Schmidt; Wong, Bang

    2012-01-01

    We’ve all done it—spent hours getting a figure just right for a paper, presenta- tion, or grant application. We use tried and true compositions, standard depic- tions, and intuitive colors and then think to ourselves, this is how you do it. Or is it? A new guide by Felice C. Frankel and Angela H........ DePace, Visual Strategies, eases the process of data presentation and enhances its effectiveness. If you seek inspiration and practical advice on how to craft more useful scientific graphics, this guide might be what you are looking for....

  14. Revisiting Professional Teacher Standards

    Science.gov (United States)

    Watson, Amanda

    2016-01-01

    The Australian Society for Music Education's (ASME) involvement in the development of professional standards for music educators was a significant and active research time in the history of the Society. As ASME celebrates its golden jubilee, it is appropriate to revisit that history and consider the future prospects of subject-specific standards.…

  15. Dark matter in the universe

    CERN Document Server

    Seigar, Marc S

    2015-01-01

    The study of dark matter, in both astrophysics and particle physics, has emerged as one of the most active and exciting topics of research in recent years. This book reviews the history behind the discovery of missing mass (or unseen mass) in the universe, and ties this into the proposed extensions to the Standard Model of Particle Physics (such as Supersymmetry), which were being proposed within the same time frame. This book is written as an introduction to these problems at the forefront of astrophysics and particle physics, with the goal of conveying the physics of dark matter to beginning undergraduate majors in scientific fields. The book goes on to describe existing and upcoming experiments and techniques, which will be used to detect dark matter either directly or indirectly.

  16. Dark Matter in 3D

    Energy Technology Data Exchange (ETDEWEB)

    Alves, Daniele S.M.; Hedri, Sonia El; Wacker, Jay G.

    2012-04-01

    We discuss the relevance of directional detection experiments in the post-discovery era and propose a method to extract the local dark matter phase space distribution from directional data. The first feature of this method is a parameterization of the dark matter distribution function in terms of integrals of motion, which can be analytically extended to infer properties of the global distribution if certain equilibrium conditions hold. The second feature of our method is a decomposition of the distribution function in moments of a model independent basis, with minimal reliance on the ansatz for its functional form. We illustrate our method using the Via Lactea II N-body simulation as well as an analytical model for the dark matter halo. We conclude that O(1000) events are necessary to measure deviations from the Standard Halo Model and constrain or measure the presence of anisotropies.

  17. Dark Matter searches at ATLAS

    CERN Document Server

    Cortes-Gonzalez, Arely; The ATLAS collaboration

    2016-01-01

    If Dark Matter interacts weakly with the Standard Model it can be produced at the LHC. It can be identified via initial state radiation (ISR) of the incoming partons, leaving a signature in the detector of the ISR particle (jet, photon, Z or W) recoiling off of the invisible Dark Matter particles, resulting in a large momentum imbalance. Many signatures of large missing transverse momentum recoiling against jets, photons, heavy-flavor quarks, weak gauge bosons or Higgs bosons provide an interesting channel for Dark Matter searches. These LHC searches complement those from (in)direct detection experiments. Results of these searches with the ATLAS experiment, in both effective field theory and simplified models with pair WIMP production are discussed. Both 8TeV and 13TeV pp collision data has been used in these results.

  18. Cold dark matter heats up.

    Science.gov (United States)

    Pontzen, Andrew; Governato, Fabio

    2014-02-13

    A principal discovery in modern cosmology is that standard model particles comprise only 5 per cent of the mass-energy budget of the Universe. In the ΛCDM paradigm, the remaining 95 per cent consists of dark energy (Λ) and cold dark matter. ΛCDM is being challenged by its apparent inability to explain the low-density 'cores' of dark matter measured at the centre of galaxies, where centrally concentrated high-density 'cusps' were predicted. But before drawing conclusions, it is necessary to include the effect of gas and stars, historically seen as passive components of galaxies. We now understand that these can inject heat energy into the cold dark matter through a coupling based on rapid gravitational potential fluctuations, explaining the observed low central densities.

  19. Sirius Matters

    CERN Document Server

    Brosch, Noah

    2008-01-01

    Since very early times Sirius was a point of attraction in the night sky. It served to synchronize calendars in antiquity and was the subject of many myths and legends, including some modern ones. It was perceived as a red star for more than 400 years, but such reports were relegated to the Mediterranean region. Astronomically, Sirius is a very bright star. This, and its present close distance to us, argues in favor of it being the target of detailed studies of stellar structure and evolution. Its binary nature, with a companion that is one of the more massive white dwarfs, is an additional reason for such studies. This book collects the published information on Sirius in an attempt to derive a coherent picture of how this system came to look as it does.

  20. Interplay of LHC and dark matter searches in the MSSM

    Directory of Open Access Journals (Sweden)

    Alexandre Arbey

    2015-12-01

    Full Text Available The Minimal Supersymmetric extension of the Standard Model (MSSM provides suitable candidates for cold dark matter. We discuss here the constraints from dark matter direct detection and cosmological dark matter density, as well as LHC data from Higgs, SUSY and monojet searches, and flavour physics data, in the context of the phenomenological MSSM (pMSSM with neutralino dark matter. We show that the complementarity of the different sectors is essential to probe the pMSSM parameter space.

  1. Searches for Dark Matter with in Events with Hadronic Activity

    CERN Document Server

    The ATLAS collaboration

    2017-01-01

    The astrophysical evidence of dark matter provides some of the most compelling clues to the nature of physics beyond the Standard Model. From these clues, ATLAS has developed a broad and systematic search program for dark matter production in LHC collisions. In the framework of Simplified models the searches are divided into invisible and visible channels, corresponding to dark matter searches, with a missing energy signature, and dark matter mediator searches, looking for bump in invariant mass distributions.

  2. Direct couplings of mimetic dark matter and their cosmological effects

    OpenAIRE

    Shen, Liuyuan; Mou, Yicen; Zheng, Yunlong; Li, Mingzhe

    2017-01-01

    The original mimetic model was proposed to take the role of dark matter. In this paper we consider possible direct interactions of the mimetic dark matter with other matter in the universe, especially the standard model particles such as baryons and photons. By imposing shift symmetry, the mimetic dark matter field can only have derivative couplings. We discuss the possibilities of generating baryon number asymmetry and cosmic birefringence in the universe based on the derivative couplings of...

  3. Language matters: an introduction.

    Science.gov (United States)

    Leap, William L; Provencher, Denis M

    2011-01-01

    That language and sexuality are closely connected is one of the enduring themes in human sexuality research. The articles in this special issue of the Journal of Homosexuality explore some of these language-centered insights as they apply to same-sex related desires, identities, and practices and to other dimensions of non-normative sexual experiences. The articles address language use over a range of geographic and social locations. The linguistic practices discussed are diverse, including the language associated with Santería, comments viewers make about gay pornography, homophobic discourse, coming out stories, stories where declarations of sexual identity are tacitly withheld, sexual messages in Black hip hop culture, assessments of urban AIDS ministries, and policies that limit transgender subjects' access to urban space. Taken together, these articles demonstrate that language matters in the everyday experience of sexual sameness and they model some of the approaches that are now being explored in language and sexuality studies.

  4. Flooded Dark Matter and S level rise

    Energy Technology Data Exchange (ETDEWEB)

    Randall, Lisa; Scholtz, Jakub [Department of Physics, Harvard University,Cambridge, MA 02138 (United States); Unwin, James [Department of Physics, University of Illinois at Chicago,Chicago, IL 60607 (United States)

    2016-03-03

    Most dark matter models set the dark matter relic density by some interaction with Standard Model particles. Such models generally assume the existence of Standard Model particles early on, with the dark matter relic density a later consequence of those interactions. Perhaps a more compelling assumption is that dark matter is not part of the Standard Model sector and a population of dark matter too is generated at the end of inflation. This democratic assumption about initial conditions does not necessarily provide a natural value for the dark matter relic density, and furthermore superficially leads to too much entropy in the dark sector relative to ordinary matter. We address the latter issue by the late decay of heavy particles produced at early times, thereby associating the dark matter relic density with the lifetime of a long-lived state. This paper investigates what it would take for this scenario to be compatible with observations in what we call Flooded Dark Matter (FDM) models and discusses several interesting consequences. One is that dark matter can be very light and furthermore, light dark matter is in some sense the most natural scenario in FDM as it is compatible with larger couplings of the decaying particle. A related consequence is that the decay of the field with the smallest coupling and hence the longest lifetime dominates the entropy and possibly the matter content of the Universe, a principle we refer to as “Maximum Baroqueness”. We also demonstrate that the dark sector should be colder than the ordinary sector, relaxing the most stringent free-streaming constraints on light dark matter candidates. We will discuss the potential implications for the core-cusp problem in a follow-up paper. The FDM framework will furthermore have interesting baryogenesis implications. One possibility is that dark matter is like the baryon asymmetry and both are simultaneously diluted by a late entropy dump. Alternatively, FDM is compatible with an elegant

  5. Matter-antimatter asymmetry

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    The Conference is devoted to a multidisciplinary study of matter-antimatter asymmetry and, in particular, from the point of view of particle physics, astrophysics and cosmology. A number of topics, such as the practical applications of antimatter in medical imaging, of particular interest to non-specialists, will also be briefly covered. More than thirty years after the discovery of CP violation in the kaon system, precision experiments with kaons at CERN and Fermilab have demonstrated the existence of direct CP violation, opening a window on a hitherto poorly explored part of particle physics. On the one hand, two experiments devoted mainly to CP violation in B mesons, BABAR and Belle, are beginning to test CP violation in the Standard Model in a decisive way. On the other hand, balloon experiments and the space-based AMS project are circumscribing precise limits on the cosmological abundance of antimatter. Finally, the fundamental problem of cosmological matter-antimatter asymmetry at a Grand Unification scale or at the Electroweak phase transition has been the object of intense theoretical activity in recent years. This document gathers most of the slides that have been presented in the plenary and parallel sessions.

  6. Z-portal dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Arcadi, Giorgio [Laboratoire de Physique Théorique Université Paris-Sud, F-91405 Orsay (France); Institute for Theoretical Physics, Georg-August University Göttingen, Friedrich-Hund-Platz 1, Göttingen, D-37077 (Germany); Mambrini, Yann [Laboratoire de Physique Théorique Université Paris-Sud, F-91405 Orsay (France); Richard, Francois [Laboratoire de l’Accélérateur Linéaire, IN2P3/CNRS and Université Paris-Sud 11 Centre Scientifique d’Orsay, B. P. 34, F-91898 Orsay Cedex (France)

    2015-03-11

    We propose to generalize the extensions of the Standard Model where the Z boson serves as a mediator between the Standard Model sector and the dark sector χ. We show that, like in the Higgs portal case, the combined constraints from the recent direct searches restrict severely the nature of the coupling of the dark matter to the Z boson and set a limit m{sub χ}≳200 GeV (except in a very narrow region around the Z-pole region). Using complementarity between spin dependent, spin independent and FERMI limits, we predict the nature of this coupling, more specifically the axial/vectorial ratio that respects a thermal dark matter coupled through a Z-portal while not being excluded by the current observations. We also show that the next generation of experiments of the type LZ or XENON1T will test Z-portal scenario for dark matter mass up to 2 TeV. The condition of a thermal dark matter naturally predicts the spin-dependent scattering cross section on the neutron to be σ{sub χn}{sup SD}≃10{sup −40} cm{sup 2}, which then becomes a clear prediction of the model and a signature testable in the near future experiments.

  7. Dark Matter searches at ATLAS

    CERN Document Server

    Schramm, S; The ATLAS collaboration

    2014-01-01

    Numerous independent astrophysical experiments have observed and measured the influence of the phenomenon named Dark Matter, but its nature is still unknown. If the assumption that Dark Matter is a particle which has a weak coupling to the Standard Model is valid, then collider searches have the ability to search for the production of this new Weakly Interacting Massive Particle (WIMP). Any Dark Matter particles produced in collisions would escape the detector without being observed. Signatures which include an initial-state radiated particle balancing a large amount of Missing Transverse Momentum, known as mono-X topologies, provide a generic means of conducting Dark Matter searches. ATLAS has conducted several mono-X searches, including recoiling jets, photons, W/Z bosons which decay hadronically, and Z bosons which decay leptonically. Searches were carried out with centre of mass energies of both 7 and 8 TeV, and with up to 20/fb of data. No evidence for physics beyond the Standard Model is observed, and t...

  8. Flavored dark matter beyond Minimal Flavor Violation

    CERN Document Server

    Agrawal, Prateek; Gemmler, Katrin

    2014-10-13

    We study the interplay of flavor and dark matter phenomenology for models of flavored dark matter interacting with quarks. We allow an arbitrary flavor structure in the coupling of dark matter with quarks. This coupling is assumed to be the only new source of violation of the Standard Model flavor symmetry extended by a $U(3)_\\chi$ associated with the dark matter. We call this ansatz Dark Minimal Flavor Violation (DMFV) and highlight its various implications, including an unbroken discrete symmetry that can stabilize the dark matter. As an illustration we study a Dirac fermionic dark matter $\\chi$ which transforms as triplet under $U(3)_\\chi$, and is a singlet under the Standard Model. The dark matter couples to right-handed down-type quarks via a colored scalar mediator $\\phi$ with a coupling $\\lambda$. We identify a number of "flavor-safe" scenarios for the structure of $\\lambda$ which are beyond Minimal Flavor Violation. For dark matter and collider phenomenology we focus on the well-motivated case of $b$-...

  9. Media matters.

    Science.gov (United States)

    Martinez, L M

    1995-01-01

    The impact of the mass media on woman's status was addressed at two 1995 conferences: the Fourth World Conference on Women, held in Beijing, China, and the Congress of the World Association for Christian Communication, held in Puebla, Mexico. The globalization process facilitated by the mass media has served to increase the power of patriarchy, with no advantages to the cause of women's rights. Coverage of popular movements has been suppressed out of deference to male-controlled governments. Coverage of the Beijing Conference highlighted celebrities and personal stories, to the exclusion of the economic and political issues under debate. Television has commodified women, reinforcing their oppression. On the other hand, the alternative media, which tend to be decentralized, democratic, low-cost, and low in technology, are presenting women as subjects rather than objects and deconstructing gender stereotypes. Of concern, however, is the tendency of computer technology to widen the gap between social classes and developed and developing countries. Women must use information networks to disseminate information on women's rights and strengthen the links between women throughout the world.

  10. An introduction to the standard model of particle physics for the non-specialist

    CERN Document Server

    Marsh, Gerald E

    2018-01-01

    This book takes the reader from some elementary ideas about groups to the essence of the Standard Model of particle physics along a relatively straight and intuitive path. Groups alone are first used to arrive at a classical analog of the Dirac equation. Using elementary quantum mechanics, this analog can be turned into the actual Dirac equation, which governs the motion of the quarks and leptons of the Standard Model. After an introduction to the gauge principle, the groups introduced in the beginning of the book are used to give an introduction to the Standard Model. The idea is to give an Olympian view of this evolution, one that is often missing when absorbing the detailed subject matter of the Standard Model as presented in an historical approach to the subject.

  11. Cortical gray matter changes in primary blepharospasm: a voxel-based morphometry study.

    Science.gov (United States)

    Martino, Davide; Di Giorgio, Annabella; D'Ambrosio, Enrico; Popolizio, Teresa; Macerollo, Antonella; Livrea, Paolo; Bertolino, Alessandro; Defazio, Giovanni

    2011-08-15

    Previous voxel-based morphometry studies of patients with primary blepharospasm documented gray matter volumetric differences of the striatum, cerebellum, thalamus, and parietal lobe areas. However, these results were inconsistent across studies, which recruited relatively small samples and did not always provide detailed clinical information on patients with blepharospasm. The objective of this study was to analyze whole-brain gray matter volume in a larger sample of patients with blepharospasm and to expand on previous works by evaluating whether clinical features of blepharospasm correlate to whole-brain gray matter changes. Voxel-based morphometry was performed on 25 patients with primary adult-onset blepharospasm and 24 healthy subjects (controls) matched for age, sex, and handedness. Clinical data were collected through a standardized interview. Severity of blepharospasm was measured using the Jankovic Rating Scale. Patients with blepharospasm had greater gray matter volume than controls in the right middle frontal gyrus, whereas patients with blepharospasm had smaller gray matter volume than controls in the left postcentral gyrus and left superior temporal gyrus. Spearman correlation analysis with Bonferroni correction failed to show significant correlations between gray matter volume and the explored clinical variables, comprising age at onset, disease duration, blepharospasm severity, presence of an effective geste antagoniste, and dose and duration of botulinum toxin treatment. Patients with blepharospasm exhibited gray matter volume differences exclusively in cortical regions highly relevant to sensory processing and cognitive modulation of motor behavior. Gray matter changes in the primary sensory cortex may represent a common trait of primary dystonias, including blepharospasm. Copyright © 2011 Movement Disorder Society.

  12. Auditors’ Assessments of Materiality Between Professional Judgment and Subjectivity

    Directory of Open Access Journals (Sweden)

    Saher Aqel

    2011-08-01

    Full Text Available Abstract: Materiality has been and continues to be a topic of importance for auditors. It is considered as a significant factor in the planning of the audit procedures, performing the planned audit procedures, evaluating the results of the audit procedures and issuing an audit report. Recently, there has been a renewed interest in the concept of materiality motivated by concerns at the Sarbanes-Oxley Act, Securities and Exchange Commission and International Auditing and Assurance Standards Board issuance of proposed standards on materiality. The objective of this paper is to discuss and analyze comprehensively the concept of audit materiality including how materiality threshold is determined by auditors. Auditing standards settings bodies pointed out that auditor’s determination of materiality threshold is a matter of professional judjment. As a judgmental concept, however, materiality is susceptible to subjectivity. Furthermore, the absence of audting standards on how materiality is determined has highlighted the significance of this issue and indicated that guidance for materiality professional judgments must come from other non-authoritative sources such as empirical researches. A number of new and important areas of materiality are in need of further investigation.

  13. ADAPTIVE OUTPUT CONTROL: SUBJECT MATTER, APPLICATION TASKS AND SOLUTIONS

    Directory of Open Access Journals (Sweden)

    Alexey A. Bobtsov

    2013-01-01

    Full Text Available The problem of adaptive output control for parametric and functionally uncertain plants is considered. Application examples illustrating the practical use of the discussed theory are given along with the mathematical formulation of the problem. A brief review of adaptive output control methods, by both linear and non-linear systems, is presented and an extensive bibliography, in which the reader will find a detailed description of the specific algorithms and their properties, is represented. A new approach to the output control problem - a method of consecutive compensator - is considered in detail.

  14. K-Means Subject Matter Expert Refined Topic Model Methodology

    Science.gov (United States)

    2017-01-01

    implementations for Case 4 only. The accuracy results for all of the SMERT/KSMERT implantations are similar due to the user employing domain knowledge to...truck. 5 The supplier welded and misdimensioned the titanium offsite. 6 The inspector drilled plastic and overheated it at station2. 7 It was...drilled and overheated. 8 It was drilled and overheated. 9 The engineer and the manager at station3 and on the truck. 10 The welded titanium was

  15. Applying Subject Matter Expertise (SME) Elicitation Techniques to TRAC Studies

    Science.gov (United States)

    2014-09-30

    in different ways. In the first case, CPR Analisys , we use the measures as way to derive effectiveness and uncertainty. In the second approach...means by which to overcome these capability gaps through the implementation of solutions, e.g., changes to doctrine, organizational structure , training...controlled through good elicitation practices, especially good question structuring , which we discuss in section C. (2) Modeling bias. This type of bias

  16. Writing for professional publication. Part 2: Subject matter.

    Science.gov (United States)

    Fowler, John

    Motivation is the first step in writing for professional publication: the next question is, what should you write about? Whatever your area of practice or level of experience, your writing will be suitable for one of the wealth of journals covering all aspects of healthcare and nursing. In this second part of a series of articles, John Fowler, an experienced nursing lecturer and author, presents some tips and suggestions to inspire you as you take your first steps on the road to writing for professional publication.

  17. Classification of educational subject matter: the case of Home ...

    African Journals Online (AJOL)

    Although it represents an individual view, this article was submitted to the Department of Education by the Cape Higher Education Consortium (CHEC) as an outcome of the review of the field of Home Economics in the Western Cape region. By presenting some history, it argues that the category of Home Economics is no ...

  18. RAn Enlarged Conception of the Subject Matter of Logic

    Directory of Open Access Journals (Sweden)

    John T. Kearns

    2004-01-01

    Full Text Available Una concepción ampliada del objeto de estudio de la lógica: El ensayo es una introducción a la lógica ilocucionaria, es decir a la lógica de los actos de habla. El autor propone una aproximación distinta a este campo de investigación con respecto al que han propuesto John Searle y Daniel Vanderveken. Ellos conciben la lógica ilocucionaria como un suplemento o un apéndice a la lógica estándar, la lógica de los enunciados, y se concentran en el estudio de leyes y principios muy generales que caracterizan todo tipo de actos ilocucionarios. Kearns, en cambio, concibe la lógica ilocucionaria como una disciplina muy comprensiva, con muchos subsistemas, que cobija a la lógica estándar como parte suya. El escrito describe brevemente el uso de los operadores ilocucionarios (de aseveración, de negación, de suposición de verdad o falsedad, explica la manera como se expande la concepción semántica en términos de condiciones de verdad para incluir los compromisos racionales del hablante y presenta un sistema de deducción para esta lógica. Como un ejemplo de lo que esta lógica puede hacer se ofrece una solución a la paradoja de Moore contenida en la aseveración “Está lloviendo, pero no lo creo”

  19. Occupational Listings Arranged by Cluster and Subject Matter Areas.

    Science.gov (United States)

    Schwarz, Otto

    Approximately 850 occupations are listed under 27 occupational clusters. The Dictionary of Occupational Title (DOT) number is specified for occupations in the clusters of business training and distributive education, chemistry, general shop and industrial arts, home economics, foreign language, music, social studies, art, agriculture, physics, and…

  20. Instructional Design: Impact of Subject Matter and Cognitive Styles.

    Science.gov (United States)

    1987-02-01

    processing, and the integration/synthesis of component parts. The haptic individual uses " bodily " perceptions, and is kinesthetically oriented. An...microcomputers, and the introduction of artificial intelligence techniques into training has permitted more effective use of computer-based instruction...instruction, the advent of more powerful and inexpensive microcomputers, and the introduction of artificial intelligence techniques into training, has permitted

  1. Does tutor subject-matter expertise influence student achievement in ...

    African Journals Online (AJOL)

    The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader). If you would like more information about how to print, save, and work with PDFs, Highwire Press provides a helpful Frequently Asked Questions about PDFs.

  2. Subjective matters: from image quality to image psychology

    Science.gov (United States)

    Fedorovskaya, Elena A.; De Ridder, Huib

    2013-03-01

    From the advent of digital imaging through several decades of studies, the human vision research community systematically focused on perceived image quality and digital artifacts due to resolution, compression, gamma, dynamic range, capture and reproduction noise, blur, etc., to help overcome existing technological challenges and shortcomings. Technological advances made digital images and digital multimedia nearly flawless in quality, and ubiquitous and pervasive in usage, provide us with the exciting but at the same time demanding possibility to turn to the domain of human experience including higher psychological functions, such as cognition, emotion, awareness, social interaction, consciousness and Self. In this paper we will outline the evolution of human centered multidisciplinary studies related to imaging and propose steps and potential foci of future research.

  3. The role of subject-matter analysis in science didactics

    DEFF Research Database (Denmark)

    Chaiklin, Seth

    to problems within science education. STEM education research can be reduced (roughly) to four major problem areas: curriculum, empirical evaluation of existing practices and conditions, didactics, and professional development, where each of these categories can be concretised further according to grade...... paper is primarily on the didactics category, and slightly on the professional development category. The purpose of this paper is to outline three significant points that have been developed within the cultural-historical tradition that have consequences for these two categories: (a) the relation...

  4. Blending critical thinking skills with the teaching of subject matter ...

    African Journals Online (AJOL)

    The study draws on Piaget and Vygotsky's theory of (social) constructivism to advance approaches and practices that teachers can employ to promote critical thinking in learners. We develop a lesson plan that incorporates critical thinking skills and show how teachers can correct egocentric and sociocentric tendencies that ...

  5. Exposing asymmetric gray matter vulnerability in amyotrophic lateral sclerosis

    Directory of Open Access Journals (Sweden)

    Matthew S. Devine

    2015-01-01

    Full Text Available Limb weakness in amyotrophic lateral sclerosis (ALS is typically asymmetric. Previous studies have identified an effect of limb dominance on onset and spread of weakness, however relative atrophy of dominant and non-dominant brain regions has not been investigated. Our objective was to use voxel-based morphometry (VBM to explore gray matter (GM asymmetry in ALS, in the context of limb dominance. 30 ALS subjects were matched with 17 healthy controls. All subjects were right-handed. Each underwent a structural MRI sequence, from which GM segmentations were generated. Patterns of GM atrophy were assessed in ALS subjects with first weakness in a right-sided limb (n = 15 or left-sided limb (n = 15. Within each group, a voxelwise comparison was also performed between native and mirror GM images, to identify regions of hemispheric GM asymmetry. Subjects with ALS showed disproportionate atrophy of the dominant (left motor cortex hand area, irrespective of the side of first limb weakness (p < 0.01. Asymmetric atrophy of the left somatosensory cortex and temporal gyri was only observed in ALS subjects with right-sided onset of limb weakness. Our VBM protocol, contrasting native and mirror images, was able to more sensitively detect asymmetric GM pathology in a small cohort, compared with standard methods. These findings indicate particular vulnerability of dominant upper limb representation in ALS, supporting previous clinical studies, and with implications for cortical organisation and selective vulnerability.

  6. Exposing asymmetric gray matter vulnerability in amyotrophic lateral sclerosis.

    Science.gov (United States)

    Devine, Matthew S; Pannek, Kerstin; Coulthard, Alan; McCombe, Pamela A; Rose, Stephen E; Henderson, Robert D

    2015-01-01

    Limb weakness in amyotrophic lateral sclerosis (ALS) is typically asymmetric. Previous studies have identified an effect of limb dominance on onset and spread of weakness, however relative atrophy of dominant and non-dominant brain regions has not been investigated. Our objective was to use voxel-based morphometry (VBM) to explore gray matter (GM) asymmetry in ALS, in the context of limb dominance. 30 ALS subjects were matched with 17 healthy controls. All subjects were right-handed. Each underwent a structural MRI sequence, from which GM segmentations were generated. Patterns of GM atrophy were assessed in ALS subjects with first weakness in a right-sided limb (n = 15) or left-sided limb (n = 15). Within each group, a voxelwise comparison was also performed between native and mirror GM images, to identify regions of hemispheric GM asymmetry. Subjects with ALS showed disproportionate atrophy of the dominant (left) motor cortex hand area, irrespective of the side of first limb weakness (p < 0.01). Asymmetric atrophy of the left somatosensory cortex and temporal gyri was only observed in ALS subjects with right-sided onset of limb weakness. Our VBM protocol, contrasting native and mirror images, was able to more sensitively detect asymmetric GM pathology in a small cohort, compared with standard methods. These findings indicate particular vulnerability of dominant upper limb representation in ALS, supporting previous clinical studies, and with implications for cortical organisation and selective vulnerability.

  7. The white matter query language: a novel approach for describing human white matter anatomy.

    Science.gov (United States)

    Wassermann, Demian; Makris, Nikos; Rathi, Yogesh; Shenton, Martha; Kikinis, Ron; Kubicki, Marek; Westin, Carl-Fredrik

    2016-12-01

    We have developed a novel method to describe human white matter anatomy using an approach that is both intuitive and simple to use, and which automatically extracts white matter tracts from diffusion MRI volumes. Further, our method simplifies the quantification and statistical analysis of white matter tracts on large diffusion MRI databases. This work reflects the careful syntactical definition of major white matter fiber tracts in the human brain based on a neuroanatomist's expert knowledge. The framework is based on a novel query language with a near-to-English textual syntax. This query language makes it possible to construct a dictionary of anatomical definitions that describe white matter tracts. The definitions include adjacent gray and white matter regions, and rules for spatial relations. This novel method makes it possible to automatically label white matter anatomy across subjects. After describing this method, we provide an example of its implementation where we encode anatomical knowledge in human white matter for ten association and 15 projection tracts per hemisphere, along with seven commissural tracts. Importantly, this novel method is comparable in accuracy to manual labeling. Finally, we present results applying this method to create a white matter atlas from 77 healthy subjects, and we use this atlas in a small proof-of-concept study to detect changes in association tracts that characterize schizophrenia.

  8. Dipolar dark matter with massive bigravity

    Energy Technology Data Exchange (ETDEWEB)

    Blanchet, Luc [GRECO Institut d’Astrophysique de Paris - UMR 7095 du CNRS,Université Pierre & Marie Curie,98" b" i" s boulevard Arago, 75014 Paris (France); Heisenberg, Lavinia [Nordita, KTH Royal Institute of Technology and Stockholm University,Roslagstullsbacken 23, 10691 Stockholm (Sweden); Department of Physics & The Oskar Klein Centre, AlbaNova University Centre,Roslagstullsbacken 21, 10691 Stockholm (Sweden)

    2015-12-14

    Massive gravity theories have been developed as viable IR modifications of gravity motivated by dark energy and the problem of the cosmological constant. On the other hand, modified gravity and modified dark matter theories were developed with the aim of solving the problems of standard cold dark matter at galactic scales. Here we propose to adapt the framework of ghost-free massive bigravity theories to reformulate the problem of dark matter at galactic scales. We investigate a promising alternative to dark matter called dipolar dark matter (DDM) in which two different species of dark matter are separately coupled to the two metrics of bigravity and are linked together by an internal vector field. We show that this model successfully reproduces the phenomenology of dark matter at galactic scales (i.e. MOND) as a result of a mechanism of gravitational polarisation. The model is safe in the gravitational sector, but because of the particular couplings of the matter fields and vector field to the metrics, a ghost in the decoupling limit is present in the dark matter sector. However, it might be possible to push the mass of the ghost beyond the strong coupling scale by an appropriate choice of the parameters of the model. Crucial questions to address in future work are the exact mass of the ghost, and the cosmological implications of the model.

  9. 42 CFR 1008.15 - Facts subject to advisory opinions.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Facts subject to advisory opinions. 1008.15 Section... Requesting Party § 1008.15 Facts subject to advisory opinions. (a) The OIG will consider requests from a requesting party for advisory opinions regarding the application of specific facts to the subject matters set...

  10. Astrophysical Probes of Dark Matter Interactions

    Science.gov (United States)

    Reece, Matthew

    The majority of matter in the universe is dark matter, made up of some particle beyond those in the Standard Model of particle physics. So far we have very little information about what dark matter is and how it interacts, except through gravity. Constraints from halo shapes and the Bullet Cluster give upper bounds on the self-interaction strength of dark matter, but these bounds are very weak: roughly the same size as nuclear physics cross sections, which are very large by the standards of particle physics. Given how little we know about dark matter, it is important to search for it in as broad a context as possible. Existing direct and indirect detection analyses are typically motivated by simple particle physics models like WIMP dark matter. This research will aim to widen the scope of searches for dark matter by considering a more complete range of particle physics models, working out their implications for astrophysical data, and interpreting existing data in terms of these new models. New models of dark matter can affect searches in a variety of ways. Signals may show up in conventional indirect detection searches, e.g. in gamma rays detected by Fermi-LAT or in antiprotons detected by AMS-02. The new particle physics content of the models could be reflected in surprising spectral shapes or other features of such signals, or in gamma rays with a different profile on the sky than expected in typical models. The PI has worked, for example, on a model in which signals may arise from a dark disk, which is just one of many possibilities. Signals of new dark matter models might also arise in more subtle ways. Structure in the dark sector could influence the development of structure in the visible sector, indirectly. For instance, a dark matter disk or other dark structures could alter the orbits of stars in the galaxy and may be detectable through detailed studies of the kinematics of stellar populations. Dark accretion disks could exist around astrophysical objects

  11. Sterile neutrino, hidden dark matter and their cosmological signatures

    Science.gov (United States)

    Das, Subinoy

    2012-12-01

    Though thermal dark matter has been the central idea behind the dark matter candidates, it is highly possible that dark matter of the universe is non-thermal in origin or it might be in thermal contact with some hidden or dark sector but not with standard model. Here we explore the cosmological bounds as well as the signatures on two types of non-thermal dark matter candidates. First we discuss a hidden dark matter with almost no interaction (or very feeble) with standard model particles so that it is not in thermal contact with visible sector but we assume it is thermalized with in a hidden sector due to some interaction. While encompassing the standard cold WIMP scenario, we do not require the freeze-out process to be non-relativistic. Rather, freeze-out may also occur when dark matter particles are semi-relativistic or relativistic. Especially we focus on the warm dark matter scenario in this set up and find the constraints on the warm dark matter mass, cross-section and hidden to visible sector temperature ratio which accounts for the observed dark-matter density, satisfies the Tremaine-Gunn bound on dark-matter phase space density and has a free-streaming length consistent with cosmological constraints on the matter power spectrum. Our method can also be applied to keV sterile neutrino dark matter which is not thermalized with standard model but is thermalized with in a dark sector. The second part of this proceeding focuses on an exotic dark matter candidate which arises from the existence of eV mass sterile neutrino through a late phase transition. Due to existence of a strong scalar force the light sterile states get trapped into stable degenerate micro nuggets. We find that its signature in matter power spectra is close to a warm dark matter candidate.

  12. Direct and Indirect Dark Matter Detection in Gauge Theories

    Energy Technology Data Exchange (ETDEWEB)

    Queiroz, Farinaldo [Federal Univ. of Paraba (Brazil)

    2013-01-01

    The Dark matter (DM) problem constitutes a key question at the interface among Particle Physics, Astrophysics and Cosmology. The observational data which have been accumulated in the last years point to an existence of non baryonic amount of DM. Since the Standard Model (SM) does not provide any candidate for such non-baryonic DM, the evidence of DM is a major indication for new physics beyond the SM. We will study in this work one of the most popular DM candidates, the so called WIMPs (Weakly Interacting Massive Particles) from a direct and indirect detection perspective. In order to approach the direct and indirect dection of DM in the context of Particle Physics in a more pedagogic way, we will begin our discussion talking about a minimal extension of the SM. Later we will work on the subject in a 3-3-1 model. Next, we will study the role of WIMPs in the Big Bang Nucleosynthesis. Lastly, we will look for indirect DM signals in the center of our galaxy using the NASA Satellite, called Fermi-LAT. Through a comprehensive analysis of the data events observed by Fermi-LAT and some background models, we will constrain the dark matter annihilation cross section for several annihilation channels and dark matter halo profiles.

  13. International Energy: Subject Thesaurus

    Energy Technology Data Exchange (ETDEWEB)

    Raridon, M.H. (ed.)

    1990-01-01

    The International Energy Subject Thesaurus contains the standard vocabulary to indexing terms (descriptors) developed and structured to build and maintain energy information databases. Involved in this cooperative task are (1) the technical staff of the USDOE Office of Scientific and Technical Information (OSTI) in cooperation with the member countries of the Energy Technology Data Exchange (ETDE) and (2) the International Nuclear Information System (INIS) staff representing the more than ninety countries and organizations recording and indexing information for the international nuclear information community. ETDE member countries are also members of the International Nuclear Information System (INIS). Nuclear information indexed and recorded for INIS by these ETDE member countries is also included in the ETDE Energy Data Base, and indexing terminology is therefore cooperatively standardized for use in both information systems. This structured vocabulary reflects the scope of international energy research, development, and technological programs and encompasses terminology derived not only from the basic sciences but also from the areas of energy resources, conservation, safety, environmental impact, and regulation.

  14. Automated Bayesian segmentation of microvascular white-matter lesions in the ACCORD-MIND study.

    Science.gov (United States)

    Herskovits, E H; Bryan, R N; Yang, F

    2008-01-01

    Automatic brain-lesion segmentation has the potential to greatly expand the analysis of the relationships between brain function and lesion locations in large-scale epidemiologic studies, such as the ACCORD-MIND study. In this manuscript we describe the design and evaluation of a Bayesian lesion-segmentation method, with the expectation that our approach would segment white-matter brain lesions in MR images without user intervention. Each ACCORD-MIND subject has T1-weighted, T2-weighted, spin-density-weighted, and FLAIR sequences. The training portion of our algorithm first registers training images to a standard coordinate space; then, it collects statistics that capture signal-intensity information, and residual spatial variability of normal structures and lesions. The classification portion of our algorithm then uses these statistics to segment lesions in images from new subjects, without the need for user intervention. We evaluated this algorithm using 42 subjects with primarily white-matter lesions from the ACCORD-MIND project. Our experiments demonstrated high classification accuracy, using an expert neuroradiologist as a standard. A Bayesian lesion-segmentation algorithm that collects multi-channel signal-intensity and spatial information from MR images of the brain shows potential for accurately segmenting brain lesions in images obtained from subjects not used in training.

  15. An introduction to particle dark matter

    CERN Document Server

    Profumo, Stefano

    2017-01-01

    What is the dark matter that fills the Universe and binds together galaxies? How was it produced? What are its interactions and particle properties?The paradigm of dark matter is one of the key developments at the interface of cosmology and elementary particle physics. It is also one of the foundations of the standard cosmological model. This book presents the state of the art in building and testing particle models for dark matter. Each chapter gives an analysis of questions, research directions, and methods within the field. More than 200 problems are included to challenge and stimulate the reader's knowledge and provide guidance in the practical implementation of the numerous 'tools of the trade' presented. Appendices summarize the basics of cosmology and particle physics needed for any quantitative understanding of particle models for dark matter.This interdisciplinary textbook is essential reading for anyone interested in the microscopic nature of dark matter as it manifests itself in particle physics ex...

  16. Scalar dark matter with type II seesaw

    Directory of Open Access Journals (Sweden)

    Arnab Dasgupta

    2014-12-01

    Full Text Available We study the possibility of generating tiny neutrino mass through a combination of type I and type II seesaw mechanism within the framework of an abelian extension of standard model. The model also provides a naturally stable dark matter candidate in terms of the lightest neutral component of a scalar doublet. We compute the relic abundance of such a dark matter candidate and also point out how the strength of type II seesaw term can affect the relic abundance of dark matter. Such a model which connects neutrino mass and dark matter abundance has the potential of being verified or ruled out in the ongoing neutrino, dark matter, as well as accelerator experiments.

  17. Cosmological Singlet Diagnostics of Neutrinophilic Dark Matter

    OpenAIRE

    Balducci, Ottavia; Hofmann, Stefan; Kassiteridis, Alexis

    2017-01-01

    The standard model (SM) of particle physics is extended by adding a fundemantal dark sector containing a dark matter singlet, which is coupled to the visible sector via a gauge invariant Yukawa portal and a sterile neutrino bridge. The cases of weakly interacting dark matter particles and feebly interacting ones are both considered. Even after the Yukawa portal is closed, the sterile neutrino bridge keeps the communication between the dark and visible sectors open, allowing for a prolonged co...

  18. Computational Science-based Research on Dark Matter at KISTI

    Science.gov (United States)

    Cho, Kihyeon

    2017-06-01

    The Standard Model of particle physics was established after discovery of the Higgs boson. However, little is known about dark matter, which has mass and constitutes approximately five times the number of standard model particles in space. The cross-section of dark matter is much smaller than that of the existing Standard Model, and the range of the predicted mass is wide, from a few eV to several PeV. Therefore, massive amounts of astronomical, accelerator, and simulation data are required to study dark matter, and efficient processing of these data is vital. Computational science, which can combine experiments, theory, and simulation, is thus necessary for dark matter research. A computational science and deep learning-based dark matter research platform is suggested for enhanced coverage and sharing of data. Such an approach can efficiently add to our existing knowledge on the mystery of dark matter.

  19. The structural neural substrate of subjective happiness.

    Science.gov (United States)

    Sato, Wataru; Kochiyama, Takanori; Uono, Shota; Kubota, Yasutaka; Sawada, Reiko; Yoshimura, Sayaka; Toichi, Motomi

    2015-11-20

    Happiness is a subjective experience that is an ultimate goal for humans. Psychological studies have shown that subjective happiness can be measured reliably and consists of emotional and cognitive components. However, the neural substrates of subjective happiness remain unclear. To investigate this issue, we used structural magnetic resonance imaging and questionnaires that assessed subjective happiness, the intensity of positive and negative emotional experiences, and purpose in life. We found a positive relationship between the subjective happiness score and gray matter volume in the right precuneus. Moreover, the same region showed an association with the combined positive and negative emotional intensity and purpose in life scores. Our findings suggest that the precuneus mediates subjective happiness by integrating the emotional and cognitive components of happiness.

  20. The structural neural substrate of subjective happiness

    Science.gov (United States)

    Sato, Wataru; Kochiyama, Takanori; Uono, Shota; Kubota, Yasutaka; Sawada, Reiko; Yoshimura, Sayaka; Toichi, Motomi

    2015-01-01

    Happiness is a subjective experience that is an ultimate goal for humans. Psychological studies have shown that subjective happiness can be measured reliably and consists of emotional and cognitive components. However, the neural substrates of subjective happiness remain unclear. To investigate this issue, we used structural magnetic resonance imaging and questionnaires that assessed subjective happiness, the intensity of positive and negative emotional experiences, and purpose in life. We found a positive relationship between the subjective happiness score and gray matter volume in the right precuneus. Moreover, the same region showed an association with the combined positive and negative emotional intensity and purpose in life scores. Our findings suggest that the precuneus mediates subjective happiness by integrating the emotional and cognitive components of happiness. PMID:26586449

  1. Searches for Dark Matter at the LHC

    CERN Document Server

    Sciolla, Gabriella; The ATLAS collaboration

    2016-01-01

    Dark Matter can be produced in large amounts in pp collisions at the Large Hadron Collider (LHC) assuming it interacts non-gravitationally with Standard Model particles. While Dark Matter escapes direct detection at the LHC, it leaves a distinct signature of significant missing transverse momentum. In this talk, recent results from the ATLAS and CMS detectors will be presented, based on events with large missing transverse momentum accompanied by a variety of other objects such as jets, photons, heavy-flavor quarks, weak gauge bosons, or Higgs bosons. These measurements are complementary to those obtained in direct and indirect Dark Matter detection experiments.

  2. Dark Matter searches with the ATLAS Detector

    CERN Document Server

    Ippolito, Valerio; The ATLAS collaboration

    2017-01-01

    The presence of a non-baryonic Dark Matter component in the Universe is inferred from the observation of its gravitational interaction. If Dark Matter interacts weakly with the Standard Model particles it may be produced at the Large Hadron Collider (LHC), escaping detection and leaving large missing transverse momentum as its signature. New results from the Dark Matter search programme of the ATLAS experiment are presented, based on LHC proton-proton collision data collected at a center-of-mass energy of 13 TeV.

  3. Dark Matter Searches with the ATLAS detector

    CERN Document Server

    Elliot, Alison; The ATLAS collaboration

    2017-01-01

    The presence of a non-baryonic dark matter component in the Universe is inferred from the observation of its gravitational interaction. If dark matter interacts weakly with the Standard Model it would be produced at the LHC, escaping the detector and leaving a large missing transverse momentum as its signature. The ATLAS detector has developed a broad and systematic search program for dark matter production in LHC collisions. The results of these searches on the first 13 TeV data, their interpretation, and the design and possible evolution of the search program will be presented.

  4. Dark Matter Searches with the ATLAS Detector

    CERN Document Server

    Elliot, Alison; The ATLAS collaboration

    2017-01-01

    The presence of a non-baryonic dark matter component in the Universe is inferred from the observation of its gravitational interaction. If dark matter interacts weakly with the Standard Model it would be produced at the LHC, escaping the detector and leaving a large missing transverse momentum as their signature.  The ATLAS detector has developed a broad and systematic search program for dark matter production in LHC collisions. The results of these searches on the first 13 TeV data, their interpretation, and the design and possible evolution of the search program will be presented.

  5. Dark matter searches with the ATLAS detector

    CERN Document Server

    Whalen, Kathleen; The ATLAS collaboration

    2017-01-01

    The presence of a non-baryonic dark matter component in the Universe is inferred from the observation of its gravitational interaction. If dark matter interacts weakly with the Standard Model it would be produced at the LHC, escaping the detector and leaving a large missing transverse momentum as its signature. The ATLAS detector has developed a broad and systematic search program for dark matter production in LHC collisions. The results of these searches using the first 13 TeV data, their interpretation, and the design and possible evolution of the search program will be presented.

  6. Dark Matter searches with the ATLAS Detector

    CERN Document Server

    Ippolito, Valerio; The ATLAS collaboration

    2017-01-01

    The presence of a non-baryonic dark matter component in the Universe is inferred from the observation of its gravitational interaction. If dark matter interacts weakly with the Standard Model it would be produced at the LHC, escaping the detector and leaving a large missing transverse momentum as their signature. The ATLAS detector has developed a broad and systematic search program for dark matter production in LHC collisions. The results of these searches on the first 13 TeV data, their interpretation, and the design and possible evolution of the search program will be presented.

  7. Hidden photons in connection to dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Andreas, Sarah; Ringwald, Andreas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Goodsell, Mark D. [CPhT, Ecole Polytechnique, Palaiseau (France)

    2013-06-15

    Light extra U(1) gauge bosons, so called hidden photons, which reside in a hidden sector have attracted much attention since they are a well motivated feature of many scenarios beyond the Standard Model and furthermore could mediate the interaction with hidden sector dark matter.We review limits on hidden photons from past electron beam dump experiments including two new limits from such experiments at KEK and Orsay. In addition, we study the possibility of having dark matter in the hidden sector. A simple toy model and different supersymmetric realisations are shown to provide viable dark matter candidates in the hidden sector that are in agreement with recent direct detection limits.

  8. Dark Matter Searches with the ATLAS detector

    Directory of Open Access Journals (Sweden)

    Elliot Alison

    2017-01-01

    Full Text Available The presence of a non-baryonic dark matter component in the Universe is inferred from the observation of its gravitational interaction. If dark matter interacts weakly with the Standard Model it would be produced at the LHC, escaping the detector and leaving a large missing transverse momentum as its signature. The ATLAS detector has developed a broad and systematic search program for dark matter production in LHC collisions. The results of these searches on the first 13 TeV data, their interpretation, and the design and possible evolution of the search program will be presented.

  9. Evidence for Functional Networks within the Human Brain's White Matter.

    Science.gov (United States)

    Peer, Michael; Nitzan, Mor; Bick, Atira S; Levin, Netta; Arzy, Shahar

    2017-07-05

    Investigation of the functional macro-scale organization of the human cortex is fundamental in modern neuroscience. Although numerous studies have identified networks of interacting functional modules in the gray-matter, limited research was directed to the functional organization of the white-matter. Recent studies have demonstrated that the white-matter exhibits blood oxygen level-dependent signal fluctuations similar to those of the gray-matter. Here we used these signal fluctuations to investigate whether the white-matter is organized as functional networks by applying a clustering analysis on resting-state functional MRI (RSfMRI) data from white-matter voxels, in 176 subjects (of both sexes). This analysis indicated the existence of 12 symmetrical white-matter functional networks, corresponding to combinations of white-matter tracts identified by diffusion tensor imaging. Six of the networks included interhemispheric commissural bridges traversing the corpus callosum. Signals in white-matter networks correlated with signals from functional gray-matter networks, providing missing knowledge on how these distributed networks communicate across large distances. These findings were replicated in an independent subject group and were corroborated by seed-based analysis in small groups and individual subjects. The identified white-matter functional atlases and analysis codes are available at http://mind.huji.ac.il/white-matter.aspx Our results demonstrate that the white-matter manifests an intrinsic functional organization as interacting networks of functional modules, similarly to the gray-matter, which can be investigated using RSfMRI. The discovery of functional networks within the white-matter may open new avenues of research in cognitive neuroscience and clinical neuropsychiatry.SIGNIFICANCE STATEMENT In recent years, functional MRI (fMRI) has revolutionized all fields of neuroscience, enabling identifications of functional modules and networks in the human

  10. White matter injury detection in neonatal MRI

    Science.gov (United States)

    Cheng, Irene; Hajari, Nasim; Firouzmanesh, Amirhossein; Shen, Rui; Miller, Steven; Poskitt, Ken; Basu, Anup

    2013-02-01

    Early detection of white matter injury in premature newborns can facilitate timely clinical treatments reducing the potential risk of later developmental deficits. It was reported that there were more than 5% premature newborns in British Columbia, Canada, among which 5-10% exhibited major motor deficits and 25-50% exhibited significant developmental and visual deficits. With the advancement of computer assisted detection systems, it is possible to automatically identify white matter injuries, which are found inside the grey matter region of the brain. Atlas registration has been suggested in the literature to distinguish grey matter from the soft tissues inside the skull. However, our subjects are premature newborns delivered at 24 to 32 weeks of gestation. During this period, the grey matter undergoes rapid changes and differs significantly from one to another. Besides, not all detected white spots represent injuries. Additional neighborhood information and expert input are required for verification. In this paper, we propose a white matter feature identification system for premature newborns, which is composed of several steps: (1) Candidate white matter segmentation; (2) Feature extraction from candidates; (3) Validation with data obtained at a later stage on the children; and (4) Feature confirmation for automated detection. The main challenge of this work lies in segmenting white matter injuries from noisy and low resolution data. Our approach integrates image fusion and contrast enhancement together with a fuzzy segmentation technique to achieve promising results. Other applications, such as brain tumor and intra-ventricular haemorrhage detection can also benefit from our approach.

  11. What does cosmology tell us about particle physics beyond the Standard Model?

    Science.gov (United States)

    Komatsu, Eiichiro

    2012-07-01

    Cosmology demands particle physics beyond the Standard Model: we need to explain the nature of dark matter and dark energy, and the physics of cosmic inflation. Cosmology also provides the tightest upper bound on the sum of neutrino masses, and it seems only a matter of time before we measure the absolute mass of neutrinos, unveiling the neutrino mass hierarchy. It also provides a measurement of the number of relativistic species at the photon decoupling epoch (at which the temperature of the universe is 3000 K). Astronomy and Astrophysics Decadal Survey conducted by USA's National Academy of Sciences has identified these four topics (dark matter, dark energy, inflation and neutrinos) as the most important subjects to study in cosmology over the next decade. In this contribution, we review the current status on these topics, in light of the recent cosmological constraints.

  12. ['Gold standard', not 'golden standard'

    NARCIS (Netherlands)

    Claassen, J.A.H.R.

    2005-01-01

    In medical literature, both 'gold standard' and 'golden standard' are employed to describe a reference test used for comparison with a novel method. The term 'gold standard' in its current sense in medical research was coined by Rudd in 1979, in reference to the monetary gold standard. In the same

  13. Vanishing White Matter Disease

    Science.gov (United States)

    ... In Memory Of Obituaries Contact Us Donate Vanishing White Matter Disease What is Vanishing White Matter Disease? ... of the genetic basis of VWM was a great step forward. First of all, it allows genetic ...

  14. Particulate Matter (PM) Pollution

    Science.gov (United States)

    ... Environmental Protection Agency Search Search Particulate Matter (PM) Pollution Contact Us Share Most PM particles form in ... and cause serious health effects. Particulate Matter (PM) Pollution PM Basics What is PM, and how does ...

  15. Mind Over Matter: Cocaine

    Science.gov (United States)

    ... Term(s): Teachers / NIDA Teaching Guide / Mind Over Matter Teaching Guide and Series / Cocaine Mind Over Matter: Cocaine Print Order Free Publication in: English Spanish Download PDF 806.08 KB Cocaine is ...

  16. Mind Over Matter: Methamphetamine

    Science.gov (United States)

    ... Term(s): Teachers / NIDA Teaching Guide / Mind Over Matter Teaching Guide and Series / Methamphetamine Mind Over Matter: Methamphetamine (Meth) Print Order Free Publication in: English Spanish Download PDF 739.54 KB Methamphetamine comes ...

  17. BARYONIC DARK MATTER ?

    OpenAIRE

    Rees, M J

    1986-01-01

    In the first two of these lectures, I present the evidence for baryonic dark matter and describe possible forms that it may take. The final lecture discusses formation of baryonic dark matter, and sets the cosmological context.

  18. The effect and safety of highly standardized Ginger (Zingiber officinale) and Echinacea (Echinacea angustifolia) extract supplementation on inflammation and chronic pain in NSAIDs poor responders. A pilot study in subjects with knee arthrosis.

    Science.gov (United States)

    Rondanelli, Mariangela; Riva, Antonella; Morazzoni, Paolo; Allegrini, Pietro; Faliva, Milena Anna; Naso, Maurizio; Miccono, Alessandra; Peroni, Gabriella; Degli Agosti, Irene; Perna, Simone

    2017-06-01

    The study aimed to evaluate the effect of Zingiber officinale and Echinacea angustifolia extract supplementation (25 mg of ginger and 5 mg of Echinacea) for 30 days on inflammation and chronic pain in knee osteoarthritis (OA). Consecutive nonsteroidal anti-inflammatory-drugs (NSAIDs) poor responders with chronic inflammation and pain due to knee arthrosis were assessed (15 subjects, age: 67.2 ± 7.9, body mass index: 30.6 ± 7.1, men/women:2/13). The primary endpoint was to determine pain improvement from baseline to Day 30 by Tegner Lysholm Knee Scoring. The secondary endpoints were the assessment of Visual Analog Scale for Pain, health-related quality of life, by the ShortForm36 (SF-36), anthropometric parameters, hydration. After supplementation, a significant improvement of 12.27 points was observed for Lysholm scale score (p < 0.05), SF-36 (p < 0.05), and a decrease in -0.52 cm in knee circumference (left) (p < 0.01). This pilot study provides feasibility and safety data for the use of highly standardised ginger and Echinacea extract supplementation in people with knee OA.

  19. Dark Matter Effective Theory

    DEFF Research Database (Denmark)

    Del Nobile, Eugenio; Sannino, Francesco

    2012-01-01

    We organize the effective (self)interaction terms for complex scalar dark matter candidates which are either an isosinglet, isodoublet or an isotriplet with respect to the weak interactions. The classification has been performed ordering the operators in inverse powers of the dark matter cutoff...... scale. We assume Lorentz invariance, color and charge neutrality. We also introduce potentially interesting dark matter induced flavor-changing operators. Our general framework allows for model independent investigations of dark matter properties....

  20. Dence Cold Matter

    Directory of Open Access Journals (Sweden)

    Stavinskiy Alexey

    2014-04-01

    Full Text Available Possible way to create dense cold baryonic matter in the laboratory is discussed. The density of this matter is comparable or even larger than the density of neutron star core. The properties of this matter can be controlled by trigger conditions. Experimental program for the study of properties of dense cold matter for light and heavy ion collisions at initial energy range √sNN~2-3GeV is proposed..

  1. Sensibility and Subjectivity: Levinas’ Traumatic Subject

    Directory of Open Access Journals (Sweden)

    Rashmika Pandya

    2011-02-01

    Full Text Available The importance of Levinas’ notions of sensibility and subjectivity are evident in the revision of phenomenological method by current phenomenologists such as Jean-Luc Marion and Michel Henry. The criticisms of key tenants of classical phenomenology, intentionality and reduction, are of a particular note. However, there are problems with Levinas’ characterization of subjectivity as essentially sensible. In “Totality and Infinity” and “Otherwise than Being”, Levinas criticizes and recasts a traditional notion of subjectivity, particularly the notion of the subject as the first and foremost rational subject. The subject in Levinas’ works is characterized more by its sensibility and affectedness than by its capacity to reason or affect its world. Levinas ties rationality to economy and suggests an alternative notion of reason that leads to his analysis of the ethical relation as the face-to-face encounter. The ‘origin’ of the social relation is located not in our capacity to know but rather in a sensibility that is diametrically opposed to the reason understood as economy. I argue that the opposition in Levinas’ thought between reason and sensibility is problematic and essentially leads to a self-conflicted subject. In fact, it would seem that violence characterizes the subject’s self-relation and, thus, is also inscribed at the base of the social relation. Rather than overcoming a problematic tendency to dualistic thought in philosophy Levinas merely reverses traditional hierarchies of reason/emotion, subject/object and self/other. 

  2. Status and Value of International Standards for Nuclear Criticality Safety

    Energy Technology Data Exchange (ETDEWEB)

    Hopper, Calvin Mitchell [ORNL

    2011-01-01

    This presentation provides an update to the author's standards report provided at the ICNC-2007 meeting. It includes a discussion about the difference between, and the value of participating in, the development of international 'consensus' standards as opposed to nonconsensus standards. Standards are developed for a myriad of reasons. Generally, standards represent an agreed upon, repeatable way of doing something as defined by an individual or group of people. They come in various types. Examples include personal, family, business, industrial, commercial, and regulatory such as military, community, state, federal, and international standards. Typically, national and international 'consensus' standards are developed by individuals and organizations of diverse backgrounds representing the subject matter users and developers of a service or product and other interested parties or organizations. Within the International Organization for Standardization (ISO), Technical Committee 85 (TC85) on nuclear energy, Subcommittee 5 (SC5) on nuclear fuel technology, there is a Working Group 8 (WG8) on standardization of calculations, procedures, and practices related to criticality safety. WG8 has developed, and is developing, ISO standards within the category of nuclear criticality safety of fissionable materials outside of reactors (i.e., nonreactor fissionable material nuclear fuel cycle facilities). Since the presentation of the ICNC-2007 report, WG8 has issued three new finalized international standards and is developing two more new standards. Nearly all elements of the published WG8 ISO standards have been incorporated into IAEA nonconsensus guides and standards. The progression of consensus standards development among international partners in a collegial environment establishes a synergy of different concepts that broadens the perspectives of the members. This breadth of perspectives benefits the working group members in their considerations of

  3. Reflections and contributions from the Council of Rectors of Private Universities (Consejo De Rectores De Universidades Privadas – CRUP for the revision of standards and professional activities subject to the degrees incorporated to the regime from Art 4

    Directory of Open Access Journals (Sweden)

    . Documento de Trabajo CRUP

    2013-05-01

    Full Text Available Considering the consensus on the need to revise the interpretation that the Council of Universities has made on Article 43 of the Higher Education Law, the experience gained over the years of its application and having introduced in the agenda of the committees of such Council the specific topic to start the treatment within the Academic Affairs Committee, we shall contribute to the debate with some reflections made within the Council of Rectors of Private Universities. The method will be predominantly exegetical, trying to unravel the true meaning of the law and its correlation with the concrete experience, which seems to have been taken away from there and therefore generates the need for its revision. The distance between the meaning and scope of the standard and the criteria and practices adopted for its implementation, is manifested in the following situations: • Increased number of careers seeking the inclusion in the regime of article 43. • Expansion of activities restricted exclusively to professional degrees. • Consultation mechanisms that demonstrate conflicts of interest. • Invasion of activities reserved for exclusivity. • Conflicts between professions incorporated into article 43. • Secondary motivations for the incorporation to the regime of article 43. • Overestimation of professions for their incorporation into the regime of art. 43. 

  4. Dark Matter Searches and Prospects at the ATLAS Experiment

    CERN Document Server

    Taylor, Wendy; The ATLAS collaboration

    2017-01-01

    Despite the recent discovery of the Higgs boson contributing to the success of the Standard Model, the large excess of dark matter in the Universe remains one of the outstanding questions in science. This excess cannot be explained by Standard Model particles. A compelling hypothesis is that dark matter comprises particles that can be produced at the LHC, called Weakly Interacting Massive Particles (WIMPs). This talk presents a number of ATLAS searches for WIMP dark matter, outlining the main theoretical benchmarks and issues in terms of complementarity with direct and indirect detection experiments, and presents the prospects for dark matter searches at future LHC runs.

  5. States of Matter

    Indian Academy of Sciences (India)

    states of matter in school. Are these the only states of matter? What distinguishes different ... can be classified based on color, or electrical properties, or whether they are organic or inorganic, or conductors .... school textbooks continue to preach that there are three states of matter. Thus, I have reduced my problem from ...

  6. Matter and Energy

    CERN Document Server

    Karam, P Andrew

    2011-01-01

    In Matter and Energy, readers will learn about the many forms of energy, the wide variety of particles in nature, and Albert Einstein's world-changing realization of how matter can be changed into pure energy. The book also examines the recent discoveries of dark matter and dark energy and the future of the universe.

  7. Nonthermal Supermassive Dark Matter

    Science.gov (United States)

    Chung, Daniel J. H.; Kolb, Edward W.; Riotto, Antonio

    1999-01-01

    We discuss several cosmological production mechanisms for nonthermal supermassive dark matter and argue that dark matter may he elementary particles of mass much greater than the weak scale. Searches for dark matter should ma be limited to weakly interacting particles with mass of the order of the weak scale, but should extend into the supermassive range as well.

  8. Direct couplings of mimetic dark matter and their cosmological effects

    Science.gov (United States)

    Shen, Liuyuan; Mou, Yicen; Zheng, Yunlong; Li, Mingzhe

    2018-01-01

    The original mimetic model was proposed to take the role of dark matter. In this paper we consider possible direct interactions of mimetic dark matter with other matter in the universe, especially standard model particles such as baryons and photons. By imposing shift symmetry, the mimetic dark matter field can only have derivative couplings. We discuss the possibilities of generating baryon number asymmetry and cosmic birefringence in the universe based on the derivative couplings of mimetic dark matter to baryons and photons. Supported by NSFC (11422543, 11653002)

  9. Heavy spin-2 Dark Matter

    Energy Technology Data Exchange (ETDEWEB)

    Babichev, Eugeny [Laboratoire de Physique Théorique, CNRS, Univ. Paris-Sud, Université Paris-Saclay,91405 Orsay (France); UPMC-CNRS, UMR7095, Institut d’Astrophysique de Paris, GReCO,98bis boulevard Arago, F-75014 Paris (France); Marzola, Luca; Raidal, Martti [National Institute of Chemical Physics and Biophysics,Rävala 10, 10143 Tallinn (Estonia); Laboratory of Theoretical Physics, Institute of Physics, University of Tartu,Ravila 14c, 50411 Tartu (Estonia); Schmidt-May, Angnis [Institut für Theoretische Physik, Eidgenössische Technische Hochschule Zürich,Wolfgang-Pauli-Strasse 27, 8093 Zürich (Switzerland); Urban, Federico; Veermäe, Hardi [National Institute of Chemical Physics and Biophysics,Rävala 10, 10143 Tallinn (Estonia); Strauss, Mikael von [UPMC-CNRS, UMR7095, Institut d’Astrophysique de Paris, GReCO,98bis boulevard Arago, F-75014 Paris (France)

    2016-09-12

    We provide further details on a recent proposal addressing the nature of the dark sectors in cosmology and demonstrate that all current observations related to Dark Matter can be explained by the presence of a heavy spin-2 particle. Massive spin-2 fields and their gravitational interactions are uniquely described by ghost-free bimetric theory, which is a minimal and natural extension of General Relativity. In this setup, the largeness of the physical Planck mass is naturally related to extremely weak couplings of the heavy spin-2 field to baryonic matter and therefore explains the absence of signals in experiments dedicated to Dark Matter searches. It also ensures the phenomenological viability of our model as we confirm by comparing it with cosmological and local tests of gravity. At the same time, the spin-2 field possesses standard gravitational interactions and it decays universally into all Standard Model fields but not into massless gravitons. Matching the measured DM abundance together with the requirement of stability constrains the spin-2 mass to be in the 1 to 100 TeV range.

  10. Standards and (self)implosion

    DEFF Research Database (Denmark)

    Brøgger, Katja; Staunæs, Dorthe

    2016-01-01

    Standards is an interesting phenomenon in discussions on emotional circulation and subjectivities. Because standards do travel. And they are usually on a mission: to standardize policies or products and consequently also those who are administered by them or consume them. Literature on the spread...

  11. Distinguishing medication-free subjects with unipolar disorder from subjects with bipolar disorder : state matters

    NARCIS (Netherlands)

    Rive, Maria M.; Redlich, Ronny; Schmaal, Lianne; Marquand, Andre F.; Dannlowski, Udo; Grotegerd, Dominik; Veltman, Dick J.; Schene, Aart H.; Ruhe, Henricus G.

    2016-01-01

    Objectives: Recent studies have indicated that pattern recognition techniques of functional magnetic resonance imaging (fMRI) data for individual classification may be valuable for distinguishing between major depressive disorder (MDD) and bipolar disorder (BD). Importantly, medication may have

  12. Distinguishing medication-free subjects with unipolar disorder from subjects with bipolar disorder: state matters

    NARCIS (Netherlands)

    Rive, M.M.; Redlich, R.; Schmaal, L.; Marquand, A.F.; Dannlowski, U.; Grotegerd, D.; Veltman, D.J.; Schene, A.H.; Ruhe, H.G.

    2016-01-01

    OBJECTIVES: Recent studies have indicated that pattern recognition techniques of functional magnetic resonance imaging (fMRI) data for individual classification may be valuable for distinguishing between major depressive disorder (MDD) and bipolar disorder (BD). Importantly, medication may have

  13. Conformal Gravity: Dark Matter and Dark Energy

    Directory of Open Access Journals (Sweden)

    Robert K. Nesbet

    2013-01-01

    Full Text Available This short review examines recent progress in understanding dark matter, dark energy, and galactic halos using theory that departs minimally from standard particle physics and cosmology. Strict conformal symmetry (local Weyl scaling covariance, postulated for all elementary massless fields, retains standard fermion and gauge boson theory but modifies Einstein–Hilbert general relativity and the Higgs scalar field model, with no new physical fields. Subgalactic phenomenology is retained. Without invoking dark matter, conformal gravity and a conformal Higgs model fit empirical data on galactic rotational velocities, galactic halos, and Hubble expansion including dark energy.

  14. Accounting standards

    NARCIS (Netherlands)

    Stellinga, B.; Mügge, D.

    2014-01-01

    The European and global regulation of accounting standards have witnessed remarkable changes over the past twenty years. In the early 1990s, EU accounting practices were fragmented along national lines and US accounting standards were the de facto global standards. Since 2005, all EU listed

  15. Impeded Dark Matter

    Energy Technology Data Exchange (ETDEWEB)

    Kopp, Joachim; Liu, Jia [PRISMA Cluster of Excellence & Mainz Institute for Theoretical Physics,Johannes Gutenberg University,Staudingerweg 7, 55099 Mainz (Germany); Slatyer, Tracy R. [Center for Theoretical Physics, Massachusetts Institute of Technology,Cambridge, MA 02139 (United States); Wang, Xiao-Ping [PRISMA Cluster of Excellence & Mainz Institute for Theoretical Physics,Johannes Gutenberg University,Staudingerweg 7, 55099 Mainz (Germany); Xue, Wei [Center for Theoretical Physics, Massachusetts Institute of Technology,Cambridge, MA 02139 (United States)

    2016-12-12

    We consider dark matter models in which the mass splitting between the dark matter particles and their annihilation products is tiny. Compared to the previously proposed Forbidden Dark Matter scenario, the mass splittings we consider are much smaller, and are allowed to be either positive or negative. To emphasize this modification, we dub our scenario “Impeded Dark Matter”. We demonstrate that Impeded Dark Matter can be easily realized without requiring tuning of model parameters. For negative mass splitting, we demonstrate that the annihilation cross-section for Impeded Dark Matter depends linearly on the dark matter velocity or may even be kinematically forbidden, making this scenario almost insensitive to constraints from the cosmic microwave background and from observations of dwarf galaxies. Accordingly, it may be possible for Impeded Dark Matter to yield observable signals in clusters or the Galactic center, with no corresponding signal in dwarfs. For positive mass splitting, we show that the annihilation cross-section is suppressed by the small mass splitting, which helps light dark matter to survive increasingly stringent constraints from indirect searches. As specific realizations for Impeded Dark Matter, we introduce a model of vector dark matter from a hidden SU(2) sector, and a composite dark matter scenario based on a QCD-like dark sector.

  16. Collapsed Dark Matter Structures

    Science.gov (United States)

    Buckley, Matthew R.; DiFranzo, Anthony

    2018-02-01

    The distributions of dark matter and baryons in the Universe are known to be very different: The dark matter resides in extended halos, while a significant fraction of the baryons have radiated away much of their initial energy and fallen deep into the potential wells. This difference in morphology leads to the widely held conclusion that dark matter cannot cool and collapse on any scale. We revisit this assumption and show that a simple model where dark matter is charged under a "dark electromagnetism" can allow dark matter to form gravitationally collapsed objects with characteristic mass scales much smaller than that of a Milky-Way-type galaxy. Though the majority of the dark matter in spiral galaxies would remain in the halo, such a model opens the possibility that galaxies and their associated dark matter play host to a significant number of collapsed substructures. The observational signatures of such structures are not well explored but potentially interesting.

  17. Collapsed Dark Matter Structures.

    Science.gov (United States)

    Buckley, Matthew R; DiFranzo, Anthony

    2018-02-02

    The distributions of dark matter and baryons in the Universe are known to be very different: The dark matter resides in extended halos, while a significant fraction of the baryons have radiated away much of their initial energy and fallen deep into the potential wells. This difference in morphology leads to the widely held conclusion that dark matter cannot cool and collapse on any scale. We revisit this assumption and show that a simple model where dark matter is charged under a "dark electromagnetism" can allow dark matter to form gravitationally collapsed objects with characteristic mass scales much smaller than that of a Milky-Way-type galaxy. Though the majority of the dark matter in spiral galaxies would remain in the halo, such a model opens the possibility that galaxies and their associated dark matter play host to a significant number of collapsed substructures. The observational signatures of such structures are not well explored but potentially interesting.

  18. How dark matter came to matter

    Science.gov (United States)

    de Swart, J. G.; Bertone, G.; van Dongen, J.

    2017-03-01

    The history of the dark matter problem can be traced back to at least the 1930s, but it was not until the early 1970s that the issue of 'missing matter' was widely recognized as problematic. In the latter period, previously separate issues involving missing mass were brought together in a single anomaly. We argue that reference to a straightforward accumulation of evidence alone is inadequate to comprehend this episode. Rather, the rise of cosmological research, the accompanying renewed interest in the theory of relativity and changes in the manpower division of astronomy in the 1960s are key to understanding how dark matter came to matter. At the same time, this story may also enlighten us on the methodological dimensions of past practices of physics and cosmology.

  19. 商業方法軟體專利之標的適格性研究 ― 以比較法之研究為中心 The Patentable Subject Matter of Business Method Patents: An Analysis from a Perspective on Comparative Law

    Directory of Open Access Journals (Sweden)

    吉玉成 Yuh-Cherng Jyi

    2004-06-01

    Full Text Available 本文於第2 部分先就商業方法軟體依軟體系統之架構予以定義,以觀察其特殊性,並作為發明專利標的適格分析之基礎。第3 部分則概述商業方法軟體之施以專利保護,對產業與專利審查實務所造成之影響。第4 部分係探討商業方法軟體是否得為發明專利之標的,而依次簡介美國法之規定與實務見解、日本特許法之規定與特許廳之態度、歐洲專利公約與專利局之立場,並由我國專利法之規定,論述絕大多數之商業方法軟體專利,其發明專利之標的適格性乃有欠缺;另就我國智慧財產局所公布之「電腦軟體相關發明專利審查基準」加以探討,及提出個人淺見,並就智慧財產局已核准商業方法軟體專利之實例,予以個案分析。第5 部分則提出個人對商業方法軟體專利之淺見及對我國未來專利保護方向之芻議,以為結 論。 This thesis first in Chapter II defines and identifies business method software under modern computer software architecture so as to form the foundation on which the patentable subject matter of business method software can be further analyzed. In Chapter III follows an overview of how patenting business method software impacts on industry and patent examination practice. Chapter IV analyzes whether business method software qualifies as patentable subject matter from a perspective on comparative legal research in American laws, Japanese laws and the European Patent Convention, and explicates that most of the business method patents granted are unqualified under the interpretation of current ROC Patent Law; this Chapter also reviews the “Examination Guidelines for Computer- Related Software Inventions” promulgated by the Intellectual Property Office from a different perspective and illustrates thereof with a business method patent granted by the Intellectual Property Office. Chapter V concludes this

  20. Dark matter and LHC: Complementarities and limitations arXiv

    CERN Document Server

    Robbins, G.; Arbey, A.; Boudaud, M.

    It is well known that dark matter density measurements, indirect and direct detection experiments, importantly complement the LHC in setting strong constraints on new physics scenarios. Yet, dark matter searches are subject to limitations which need to be considered for realistic analyses. For illustration, we explore the parameter space of the phenomenological MSSM and discuss the interplay of the constraints from dark matter searches and the LHC, and analyse the impact of the astrophysical uncertainties in some detail.

  1. Dark Forces and Light Dark Matter

    Energy Technology Data Exchange (ETDEWEB)

    Hooper, Dan [Fermi National Accelerator Laboratory (FNAL), Batavia, IL (United States); Weiner, Neal [New York Univ., NY (United States); Xue, Wei [Rue University (Canada)

    2012-09-01

    We consider a simple class of models in which the dark matter, X, is coupled to a new gauge boson, phi, with a relatively low mass (m_phi \\sim 100 MeV-3 GeV). Neither the dark matter nor the new gauge boson have tree-level couplings to the Standard Model. The dark matter in this model annihilates to phi pairs, and for a coupling of g_X \\sim 0.06 (m_X/10 GeV)^1/2 yields a thermal relic abundance consistent with the cosmological density of dark matter. The phi's produced in such annihilations decay through a small degree of kinetic mixing with the photon to combinations of Standard Model leptons and mesons. For dark matter with a mass of \\sim10 GeV, the shape of the resulting gamma-ray spectrum provides a good fit to that observed from the Galactic Center, and can also provide the very hard electron spectrum required to account for the observed synchrotron emission from the Milky Way's radio filaments. For kinetic mixing near the level naively expected from loop-suppressed operators (epsilon \\sim 10^{-4}), the dark matter is predicted to scatter elastically with protons with a cross section consistent with that required to accommodate the signals reported by DAMA/LIBRA, CoGeNT and CRESST-II.

  2. Motives matter: a cultural historical approach to IT mediated subject matter teaching

    DEFF Research Database (Denmark)

    Stenild, Kåre; Iversen, Ole Sejer

    2011-01-01

    The contributors to this collection employ the analytic resources of cultural-historical theory to examine the relationship between childhood and children's development under different societal conditions. In particular they attend to relationships between development, emotions, motives and ident......The contributors to this collection employ the analytic resources of cultural-historical theory to examine the relationship between childhood and children's development under different societal conditions. In particular they attend to relationships between development, emotions, motives...

  3. Matters of Life and Longing

    DEFF Research Database (Denmark)

    Dalsgaard, Anne Line

    of the ways that phenomenology can be used as a tool of critical social analysis. The book focuses on lived experience and subjective meaning within a life-world dominated by poverty and violence. Through a focus on the basic human need for recognition Dalsgaard describes women’s desire to be valuable...... from simplistic dichotomies of mind/body, history/biography in an effort to grasp human experience in its complexity. “Matters of Life and Longing” is a lucid and accessible work which will be of interest to a wide and varied audience with interest in Latin America, reproductive health, gender studies...

  4. Nuclear Energy Standards. KWIC index

    Energy Technology Data Exchange (ETDEWEB)

    1984-01-01

    The KWIC Index is an alphabetical listing that provides rapid identification of NE standards based upon the specific subject areas. This index facilitates identification of a NE standard by major or key words located in the center of the alphabetical index listing. Alphanumerical designations for specific NE standards are shown in the right-hand column. Standards referenced in this listing include those that are active, inactive, or discontinued.

  5. Dirac Neutrino Dark Matter

    CERN Document Server

    Bélanger, Genevieve; Servant, Géraldine

    2008-01-01

    We investigate the possibility that dark matter is made of heavy Dirac neutrinos with mass in the range [O(1) GeV- a few TeV] and with suppressed but non-zero coupling to the Standard Model Z as well as a coupling to an additional Z' gauge boson. The first part of this paper provides a model-independent analysis for the relic density and direct detection in terms of four main parameters: the mass, the couplings to the Z, to the Z' and to the Higgs. These WIMP candidates arise naturally as Kaluza-Klein states in extra-dimensional models with extended electroweak gauge group SU(2)_L* SU(2)_R * U(1). They can be stable because of Kaluza-Klein parity or of other discrete symmetries related to baryon number for instance, or even, in the low mass and low coupling limits, just because of a phase-space-suppressed decay width. An interesting aspect of warped models is that the extra Z' typically couples only to the third generation, thus avoiding the usual experimental constraints. In the second part of the paper, we ...

  6. New bound on low reheating temperature for dark matter in models with early matter domination

    Science.gov (United States)

    Choi, Ki-Young; Takahashi, Tomo

    2017-08-01

    We investigate a new bound on the low reheating temperature in a scenario where the Universe experiences early matter domination before reheating after which the standard big bang cosmology begins. In many models of dark matter (DM), the small scale fluctuations of DM grow during the early matter-domination era and seed the formation of the ultracompact minihalos (UCMHs). Using the constraints on the number of UCMHs from gamma-ray observations, we find a lower bound on the reheating temperature between O (10 )-O (100 ) MeV for WIMP dark matter depending on the nature of DM. A similar bound could be obtained for non-WIMP dark matter by observing UCMHs gravitationally such as pulsar timing, microlensing and so on, in some future observations.

  7. Inferring Beliefs as Subjectively Imprecise Probabilities

    DEFF Research Database (Denmark)

    Andersen, Steffen; Fountain, John; Harrison, Glenn W.

    2012-01-01

    . The experimental task consists of a series of standard lottery choices in which the subject is assumed to use conventional risk attitudes to select one lottery or the other and then a series of betting choices in which the subject is presented with a range of bookies offering odds on the outcome of some event...

  8. Silage quality, dry matter intake and digestibility by West African ...

    African Journals Online (AJOL)

    Grass mixtures were subjected to silage for 42 days. Quality and chemical composition of the silage was assessed. Silage was also fed to WAD sheep to determine the dry matter intake (DMI) and dry matter digestibility (DMD). Crude protein for 4WGG was 17.5% higher than that of 12WGG. Silage colour was normal except ...

  9. Understanding Physical Educators' Perceptions of Mattering Questionnaire--Physical Education

    Science.gov (United States)

    Richards, K. Andrew R.; Gaudreault, Karen Lux; Woods, Amelia Mays

    2017-01-01

    Previous research has illustrated that physical educators feel their subject is valued less than others in the context of schools. However, to date, no instruments have been developed to measure physical education teachers' perceptions of mattering. This study sought to propose and validate the Perceived Mattering Questionnaire--Physical Education…

  10. Higgs portal dark matter at the LHC

    Science.gov (United States)

    Westhoff, Susanne

    2017-11-01

    The hypothesis of dark matter interacting with the standard model uniquely via the Higgs portal is severely challenged by experiments. However, if dark matter is a fermion, the Higgs-portal interaction implies the presence of mediators, which can change the phenomenology significantly. This contribution discusses the impact of weakly-interacting mediators on the dark-matter relic abundance, direct detection, and collider searches. At the LHC, a typical signature of Higgs-portal fermion dark matter features soft leptons and missing energy, similarly to gaugino production in models with supersymmetry. We suggest to re-interpret existing gaugino searches in the context of Higgs-portal models and to extend future searches to the broader class of dark sectors with weakly-interacting fermions.

  11. Higgs Portal Inflation with Fermionic Dark Matter

    Directory of Open Access Journals (Sweden)

    Aravind Aditya

    2018-01-01

    Full Text Available We discuss the inflationary model presented in [1], involving a gauge singlet scalar field and fermionic dark matter added to the standard model. Either the Higgs or the singlet scalar could play the role of the inflaton, and slow roll is realized through its non-minimal coupling to gravity. The effective scalar potential is stabilized by the mixing between the scalars as well as the coupling with the fermionic field. Mixing of the two scalars also provides a portal to dark matter. Constraints on the model come from perturbativity and stability, collider searches and dark matter constraints and impose a constraining relationship on the masses of dark matter and scalar fields. Inflationary predictions are generically consistent with current Planck data.

  12. Higgs Portal Inflation with Fermionic Dark Matter

    Science.gov (United States)

    Aravind, Aditya; Xiao, Minglei; Yu, Jiang-Hao

    2018-01-01

    We discuss the inflationary model presented in [1], involving a gauge singlet scalar field and fermionic dark matter added to the standard model. Either the Higgs or the singlet scalar could play the role of the inflaton, and slow roll is realized through its non-minimal coupling to gravity. The effective scalar potential is stabilized by the mixing between the scalars as well as the coupling with the fermionic field. Mixing of the two scalars also provides a portal to dark matter. Constraints on the model come from perturbativity and stability, collider searches and dark matter constraints and impose a constraining relationship on the masses of dark matter and scalar fields. Inflationary predictions are generically consistent with current Planck data.

  13. Communications standards

    CERN Document Server

    Stokes, A V

    1986-01-01

    Communications Standards deals with the standardization of computer communication networks. This book examines the types of local area networks (LANs) that have been developed and looks at some of the relevant protocols in more detail. The work of Project 802 is briefly discussed, along with a protocol which has developed from one of the LAN standards and is now a de facto standard in one particular area, namely the Manufacturing Automation Protocol (MAP). Factors that affect the usage of networks, such as network management and security, are also considered. This book is divided into three se

  14. Multi-Component Dark Matter: the vector and fermion case

    OpenAIRE

    Ahmed, Aqeel; Duch, Mateusz; Grzadkowski, Bohdan; Iglicki, Michal

    2017-01-01

    A generic 2-3 component dark matter setup has been discussed. Dark matter candidates have been stabilized by a discrete $Z_2 \\!\\times\\! Z_2^\\prime$ symmetry. It turns out that non-trivial and interesting implications of multi-component dark sector emerge if standard annihilation channels are suppressed. In that case semi-annihilations, conversions and decays are crucial for the evolution of the dark matter abundance and its present value. The generic observations have been illustrated within ...

  15. Standard Model

    CERN Document Server

    Dominguez, Daniel

    2015-01-01

    All matter around us is made of elementary particles, the building blocks of matter. These particles occur in two basic types called quarks and leptons. Each group consists of six particles, which are related in pairs, or “generations”. The lightest and most stable particles make up the first generation, whereas the heavier and less stable particles belong to the second and third generations. All stable matter in the universe is made from particles that belong to the first generation; any heavier particles quickly decay to the next most stable level. The six quarks are paired in the three generations – the “up quark” and the “down quark” form the first generation, followed by the “charm quark” and “strange quark”, then the “top quark” and “bottom (or beauty) quark”. Quarks also come in three different “colours” and only mix in such ways as to form colourless objects. The six leptons are similarly arranged in three generations – the “electron” and the “electron neutrin...

  16. An International Centre for Standards Documentation: Proposals for Standardization of UDC Usage and the Mechanized Documentation of Information on Standards.

    Science.gov (United States)

    Wellisch, Hans

    At present, there are several obstacles to efficient information retrieval regarding the world's standards. There is no uniformity in subject classification, although most standards are classified by the Universal Decimal Classification (UDC); there are no international indexes to the subjects covered; foreign standards and superseded standards…

  17. Neutrino interactions in neutron matter

    Science.gov (United States)

    Cipollone, Andrea

    2012-12-01

    Neutrino flow is the dominant mechanism of energy transfer in the latest stages of supernovae explosions and in compact stars. The Standard Model of particle physics and accelerator data, provide a satisfactory description of neutrino physics in vacuum up to TeV scale. Nevertheless modeling the dynamics of neutrino interaction in the nuclear environment involves severe difficulties. This thesis in mainly aimed at obtaining the weak response of infinite matter, using both the Correlated Basis Function theory and Landau Theory of Fermi liquid to take into account properly nucleon-nucleon hard core potential and long range correlation (quasi-particle, collective modes, ecc.)

  18. Dark matter searches in ATLAS

    CERN Document Server

    Diehl, Edward; The ATLAS collaboration

    2016-01-01

    Dark matter particles may be produced at the LHC in combination with other particles, typically from initial state radiation. We present results from the ATLAS experiment from searches for phenomena with jets, photons, heavy quarks, electroweak gauge bosons, or Higgs bosons recoiling against large missing transverse momentum. The measurements are interpreted using several theoretical frameworks including simplified models with pair production of Weakly Interacting Massive Particles, effective field theories, and other beyond the Standard Model scenarios. Constraints from dijet searches are compared with results from the “Mono-X” searches to provide a combined interpretation in the context of simplified models.

  19. Codecaying Dark Matter.

    Science.gov (United States)

    Dror, Jeff Asaf; Kuflik, Eric; Ng, Wee Hao

    2016-11-18

    We propose a new mechanism for thermal dark matter freeze-out, called codecaying dark matter. Multicomponent dark sectors with degenerate particles and out-of-equilibrium decays can codecay to obtain the observed relic density. The dark matter density is exponentially depleted through the decay of nearly degenerate particles rather than from Boltzmann suppression. The relic abundance is set by the dark matter annihilation cross section, which is predicted to be boosted, and the decay rate of the dark sector particles. The mechanism is viable in a broad range of dark matter parameter space, with a robust prediction of an enhanced indirect detection signal. Finally, we present a simple model that realizes codecaying dark matter.

  20. Elementary Goldstone Higgs Boson and Dark Matter

    DEFF Research Database (Denmark)

    Alanne, Tommi; Gertov, Helene; Sannino, Francesco

    2015-01-01

    We investigate a perturbative extension of the Standard Model featuring elementary pseudo-Goldstone Higgs and dark matter particles. These are two of the five Goldstone bosons parametrising the SU(4)/Sp(4) coset space. They acquire masses, and therefore become pseudo-Goldstone bosons, due...... of the theory, the quantum corrections are precisely calculable. The remaining pseudo-Goldstone boson is identified with the dark matter candidate because it is neutral with respect to the Standard Model and stable. By a direct comparison with the Large Hadron Collider experiments, the model is found...... to be phenomenologically viable. Furthermore the dark matter particle leads to the observed thermal relic density while respecting the most stringent current experimental constraints....