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Sample records for students aged 13-15

  1. Prevalence of and susceptibility to cigarette smoking among female students aged 13 to 15 years in Vietnam, 2007.

    Science.gov (United States)

    Minh, Hoang Van; Hai, Phan Thi; Giang, Kim Bao; Kinh, Ly Ngoc

    2010-01-01

    Recent reports show a sharp increase in smoking rates among girls. We describe prevalence of cigarette smoking and susceptibility to cigarette smoking among female students aged 13 to 15 years in Vietnam and examine the associated factors. We used data from female secondary school students aged 13 to 15 years (grades 8-10) from the 2007 Global Youth Tobacco Survey that was conducted in 9 provinces in Vietnam. We used multivariate logistic regression analysis to determine associations between independent variables with smoking status and susceptibility to smoking. Prevalence of cigarette smoking among girls was 1.2% (95% confidence interval [CI], 0.9-1.5), and 1.5% (95% CI, 1.2-1.9) of girls were susceptible to smoking. Having friends who smoke was the strongest predictor of both smoking status and susceptibility to smoking. Attendance at school classes that described the harmful effects of smoking had significant effects in reducing cigarette smoking. Girls who were exposed to billboard cigarette advertising were more likely to be susceptible to smoking than were those who had not seen advertisements. Our findings highlight the need for pursuing school-based intervention programs in Vietnam and for countering tobacco advertising and marketing practices that target young women.

  2. Current Tobacco Smoking and Desire to Quit Smoking Among Students Aged 13-15 Years - Global Youth Tobacco Survey, 61 Countries, 2012-2015.

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    Arrazola, René A; Ahluwalia, Indu B; Pun, Eugene; Garcia de Quevedo, Isabel; Babb, Stephen; Armour, Brian S

    2017-05-26

    Tobacco use is the world's leading cause of preventable morbidity and mortality, resulting in nearly 6 million deaths each year (1). Smoked tobacco products, such as cigarettes and cigars, are the most common form of tobacco consumed worldwide (2), and most tobacco smokers begin smoking during adolescence (3). The health benefits of quitting are greater for persons who stop smoking at earlier ages; however, quitting smoking at any age has health benefits (4). CDC used the Global Youth Tobacco Survey (GYTS) data from 61 countries across the six World Health Organization (WHO) regions from 2012 to 2015 to examine the prevalence of current tobacco smoking and desire to quit smoking among students aged 13-15 years. Across all 61 countries, the median current tobacco smoking prevalence among students aged 13-15 years was 10.7% (range = 1.7%, Sri Lanka to 35.0%, Timor-Leste). By sex, the median current tobacco smoking prevalence was 14.6% among males (range = 2.9%, Tajikistan to 61.4%, Timor-Leste) and 7.5% among females (range = 1.6%, Tajikistan to 29.0%, Bulgaria). In the majority of countries assessed, the proportion of current tobacco smokers who desired to quit smoking exceeded 50%. These findings could be used by country level tobacco control programs to inform strategies to prevent and reduce youth tobacco use (1,4).

  3. Current Cigarette Smoking, Access, and Purchases from Retail Outlets Among Students Aged 13-15 Years - Global Youth Tobacco Survey, 45 Countries, 2013 and 2014.

    Science.gov (United States)

    D'Angelo, Denise; Ahluwalia, Indu B; Pun, Eugene; Yin, Shaoman; Palipudi, Krishna; Mbulo, Lazarous

    2016-09-02

    Tobacco use is a leading preventable cause of morbidity and mortality, with nearly 6 million deaths caused by tobacco use worldwide every year (1). Cigarette smoking is the most common form of tobacco use in most countries, and the majority of adult smokers initiate smoking before age 18 years (2,3). Limiting access to cigarettes among youths is an effective strategy to curb the tobacco epidemic by preventing smoking initiation and reducing the number of new smokers (3,4). CDC used the Global Youth Tobacco Survey (GYTS) data from 45 countries to examine the prevalence of current cigarette smoking, purchase of cigarettes from retail outlets, and type of cigarette purchases made among school students aged 13-15 years. The results are presented by the six World Health Organization (WHO) regions: African Region (AFR); Eastern Mediterranean Region (EMR); European Region (EUR); Region of the Americas (AMR); South-East Asian Region (SEAR); and Western Pacific Region (WPR). Across all 45 countries, the median overall current cigarette smoking prevalence among students aged 13-15 years was 6.8% (range = 1.7% [Kazakhstan]-28.9% [Timor-Leste]); the median prevalence among boys was 9.7% (2.0% [Kazakhstan]-53.5% [Timor-Leste]), and among girls was 3.5% (0.0% [Bangladesh]-26.3% [Italy]). The proportion of current cigarette smokers aged 13-15 years who reported purchasing cigarettes from a retail outlet such as a store, street vendor, or kiosk during the past 30 days ranged from 14.9% [Latvia] to 95.1% [Montenegro], and in approximately half the countries, exceeded 50%. In the majority of countries assessed in AFR and SEAR, approximately 40% of cigarette smokers aged 13-15 years reported purchasing individual cigarettes. Approximately half of smokers in all but one country assessed in EUR reported purchasing cigarettes in packs. These findings could be used by countries to inform tobacco control strategies in the retail environment to reduce and prevent marketing and sales of

  4. Exposure to Tobacco Advertising and Promotion among School Children Aged 13-15 in Vietnam - an Overview from GYTS 2014.

    Science.gov (United States)

    Long, Tran Khanh; Son, Phung Xuan; Giang, Kim Bao; Hai, Phan Thi; Huyen, Doan Thi Thu; Khue, Luong Ngoc; Nga, Pham Thi Quynh; Lam, Nguyen Tuan; Minh, Hoang Van; Huong, Le Thi Thanh

    2016-01-01

    Evidence shows that tobacco advertising and promotion activities may increase tobacco consumption and usage, especially in youth. Despite the regulation on prohibiting advertisement of any tobacco product, tobacco advertisement and promotion activities are still common in Vietnam. This article presents current exposure to tobacco advertising and promotion (TAP) among school children aged 13 to 15 years in Vietnam in 2014 and potential influencing factors. Data from the Global Youth Tobacco Survey 2014 in Vietnam covering 3,430 school aged children were used. Both descriptive and analytical statistics were carried out with Stata 13 statistical software. Binary logistic regression was applied to explain the exposure to TAP among youth and examine relationships with individual factors. A significance level of padvertising or promotion. Wearing or otherwise using products related to tobacco was the most exposure TAP type reported by students (22.3%). The internet (22.1), points of sales (19.2) and social events (11.5) were three places that students aged 13-15 frequently were exposed to TAP. Binary logistic results showed that gender (female vs male) (OR = 0.61, 95%CI: 0.52 - 0.71), susceptibility to smoking (OR = 2.12, 95%CI: 1.53 - 2.92), closest friends' smoked (OR = 1.43, 95%CI: 1.2 - 1.7) and parents smoking status (OR = 2.83, 95%CI: 1.6 - 5.01) were significantly associated with TAP exposure among school-aged children. The research findings should contribute to effective implementation of measures for preventing and controlling tobacco use among students aged 13-15 in Viet Nam.

  5. Cigarette Smoking among Adolescents aged 13-15 in Viet Nam and Correlates of Current Cigarette Smoking: Results from GYTS 2014 Data.

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    Huong, Le Thi; Vu, Nga Thi Thu; Dung, Nguyen Ngoc; Xuan, Le Thi Thanh; Giang, Kim Bao; Hai, Phan Thi; Huyen, Doan Thu; Khue, Luong Ngoc; Lam, Nguyen Tuan; Minh, Hoang Van; Nga, Pham Thi Quynh

    2016-01-01

    The aim of this paper is to report the rate of current and ever cigarette smoking and explore correlates of current cigarette smoking among adolescents aged 13-15 in Viet Nam. This analysis was derived from GYTS survey, which comprised of 3,430 adolescents aged 13-15, conducted in 2014 in 13 cities and provinces of Viet Nam. We calculated the weighted rates of current and ever cigarette smoking and reported patterns of smoking behavior. We also performed logistic regression to explore correlates of current cigarette smoking behavior. The weighted rate of ever cigarette smoking was 9.5% (95% confidence interval (CI): 8.5 %-10.5%), in which the weighted rate among males (15.4%; 95% CI: 13.6%-17.0%) was higher than that among females (4.2%; 95% CI: 3.3%-5.1%). The weighted rate of current cigarette smoking was relatively low at 2.5% (95%CI: 2.0%- 3.0%) with higher weighted rate among males (4.9%; 95% CI: 3.8%-5.9%) compared to the corresponding figure among females (0.2%; 95% CI: 0.0 %-0.5%). Current cigarette smoking was significantly higher among males than females, in students aged 15 versus 13 years old, and in students who had several or all close friends smoking and students with daily observation of smoking at school. For greater smoking reduction outcomes, we recommend that tobacco interventions for adolescents should consider targeting more male students at older ages, establish stricter adherence to school-based banning of cigarette smoking, engage both smoking and nonsmoking adolescents and empower adolescents to resist peer smoking influence as well as changing their norms or beliefs towards smoking benefits.

  6. Effects of individual characteristics and school environment on cigarette smoking among students ages 13-15: A multilevel analysis of the 2007 Global Youth Tobacco Survey (GYTS) data from Vietnam.

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    Van Minh, Hoang; Hai, Phan Thi; Giang, Kim Bao; Nga, Pham Quynh; Khanh, Pham Huyen; Lam, Nguyen Tuan; Kinh, Ly Ngoc

    2011-01-01

    This paper aims to estimate the prevalence of cigarette smoking among students in Vietnam ages 13-15 and examines its relationship with compositional and contextual factors. The data used in this paper were obtained from the 2007 Global Youth Tobacco Survey conducted in nine provinces in Vietnam. A multilevel logistic regression model was applied to analyse the association between the current incidence of cigarette smoking and factors on both the individual and school level. The prevalence of cigarette smoking among students was 3.3% overall. The prevalence of smoking among male students (5.9%) was higher than that among females (1.2%). Parental smoking was a significant risk factor for smoking among the students. Having a friend who smoked was the strongest predictor of smoking status among the study subjects. We have demonstrated that school-level factors appeared to impact the prevalence of cigarette smoking among students ages 13-15. This paper highlights the importance of utilising an extensive range of actions to prevent students from using tobacco in Vietnam. These actions should include providing specific curricula for students that address both individual characteristics and the school environment. Further, prevention programmes should also target both parental- and peer-smoking issues.

  7. Suicidal ideation and associated factors among students aged 13-15 years in Association of Southeast Asian Nations (ASEAN) member states, 2007-2013.

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    Peltzer, Karl; Pengpid, Supa

    2017-09-01

    The aim of this study was to assess suicidal ideation and associated factors in school-going adolescents in the Association of Southeast Asian Nations (ASEAN) member states. The analysis included 30,284 school children aged 13-15 years from seven ASEAN countries that participated in the cross-sectional global school-based student health survey (GSHS) between 2007 and 2013. The overall prevalence of suicidal ideation in the past 12 months across seven ASEAN countries was 12.3%, significantly higher in girls (15.1%) than boys (9.3%). Among seven ASEAN countries with the highest prevalence of suicidal ideation was in the Philippines (17.0%) and Vietnam (16.9%) and the lowest in Myanmar (1.1%) and Indonesia (4.2%). In multivariable logistic regression analysis, female gender, older age (14 or 15 years), living in a lower middle income country, having no friends, loneliness, bullying victimisation, having been in a physical fight in the past 12 months, lack of parental or guardian support, tobacco use and having a history of ever got drunk were associated with suicidal ideation. Different rates of suicidal ideation were observed in ASEAN member states. Several risk factors for suicidal ideation were identified which can help guide preventive efforts.

  8. Leisure Time Physical Inactivity and Sedentary Behaviour and Lifestyle Correlates among Students Aged 1315 in the Association of Southeast Asian Nations (ASEAN) Member States, 2007–2013

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    Karl Peltzer; Supa Pengpid

    2016-01-01

    The aim of this study was to examine the relationship between self-reported leisure time physical inactivity frequency and sedentary behaviour and lifestyle correlates among school children in the Association of Southeast Asian Nations (ASEAN) region. The analysis included 30,284 school children aged 13?15 years from seven ASEAN countries that participated in the Global School-based Student Health Survey (GSHS) between 2007 and 2013. The measure asked about overall physical activity, walking ...

  9. Selected atherosclerosis risk factors in youth aged 1315 years 

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    Agnieszka Michalska

    2012-09-01

    Full Text Available Introduction:The high frequency of cases of circulatory system conditions in Europe and other countries around the world requires scientific research to define risk factors of early atherosclerotic changes. The aim of the present study was to define which students are at danger of developing atherosclerosis by means of measuring cholesterol and triglyceride levels in blood as well as defining the correlation between atherosclerosis risk factors and arterial blood pressure, physical fitness and efficiency of the subjects.Material/Methods:The research covered 167 students of Public Junior High School ¹1 in Biala Podlaska aged 1315 years. Accutrend GCT was employed to define the levels of total cholesterol and triglycerides in the screen test. Those students who were found to have increased values of biochemical parameters of capillary blood were subjected to additional blood tests aiming to define complete lipid profile of venous blood. The blood pressure in subjects was tested three times. The Moderate-to-Vigorous Physical Activity (MVPA test, suggested by American authors, was employed to define physical activity in subjects. EUROFIT was employed to define physical efficiency.Results:Among the 167 subjects there were found 42 students (25.1�20whose lipid level in capillary blood proved to be increased. Full lipid profile tests proved that 16 students (9.6�20had increased blood lipid levels; those subjects constituted the risk group. Subjects in the risk group were characterized by lower levels of physical activity and physical efficiency compared to subjects with normal blood lipid level. Moreover, the frequency of hypertension was greater in risk group subjects compared to subjects with normal blood lipid levels.Inferences:Students diagnosed with atherosclerosis risk factors require observation and early prophylactics by adopting habits of healthy physical activity.

  10. Effects of Swimming Training on Stress Levels of the Students Aged 11-13

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    Köroglu, Mihraç; Yigiter, Korkmaz

    2016-01-01

    The purpose of this research was to determine the effects of the swimming training program on stress levels of the students ages 11-13. To this end, 60 students from Private Sahin School in the Sakarya city participated in the study voluntarily. 60 students were divided into two groups and each group was included 30 students. Stress Level Scale II…

  11. Prevalence of Sports Injuries Among 13- to 15-Year-Old Students in 25 Low- and Middle-Income Countries.

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    Street, Erica J; Jacobsen, Kathryn H

    2017-04-01

    The goal of this study was to compare the sex-specific prevalence rate of serious sports injuries in the past year among students ages 13-15 years from 25 low- and middle-income countries (LMICs) globally. Data from 46,922 nationally-representative students who participated in the Global School-based Student Health Survey (GSHS) were analyzed using complex samples analysis. The GSHS defines injuries as serious when they cause at least one full day of missed school or usual activities or require clinical treatment. Students reporting more than one serious injury in the past year are asked about the single most serious injury. The proportion of students reporting at least one serious injury in the past year ranged from 15-71 % (median 44 %) among boys and 8-70 % (median 30 %) among girls. The proportion of most-serious injuries in the past year that were sports-related ranged from 25-60 % among injured boys (median 35 %) and 12-56 % among injured girls (median 24 %). The most common types of sports-related injuries were broken bones and dislocated joints, reported by 13-62 % (median 28 %) of boys with sports injuries and 10-86 % (median 25 %) of girls with sports injuries. Although the annual injury rates among early adolescents vary widely between countries, the GSHS shows that sports injuries are common globally among both male and female middle school students. Understanding global trends in the health risks for various population groups, such as adolescents, allows community health partnerships to proactively address health needs in the communities they serve.

  12. Prevalence, demographic and psychosocial correlates for school truancy among students aged 13-15 in the Association of Southeast Asian Nations (ASEAN) member states.

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    Pengpid, Supa; Peltzer, Karl

    2017-11-01

    Truancy among adolescents may negatively affect the achievement of academic goals. The aim of the study was to investigate the prevalence and correlates of school truancy in the Association of Southeast Asian Nations (ASEAN) member states. The analysis included 28 419 school children aged 13-15 years from seven ASEAN member states that participated in the Global School-based Student Health Survey (GSHS) between 2007 and 2013. The overall prevalence of past 30 day truancy across six ASEAN countries (excluding Brunei) was 24.8%; ranging from below 20% in Myanmar, Thailand, and Vietnam to more than 30% in Brunei Darussalam, Indonesia, and the Philippines. In multivariable logistic regression analysis, socio-demographic factors (older age, being male, the experience of hunger), externalising behaviour (tobacco use, alcohol use, having been in a physical fight, being bullied, having sustained an injury), and lack of protective social-familial factors (lack of peer support and lack of parental or guardian support) were found to be associated with truancy. High rates of truancy were found in ASEAN member states calling for interventions aimed to reduce truancy considering identified associated factors.

  13. Linking data to tobacco control program action among students aged 13-15 in Association of Southeast Asian Nations (ASEAN) member states, 2000-2006.

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    Sirichotiratana, N; Sovann, S; Aditama, T Y; Krishnan, M; Kyaing, N N; Miguel-Baquilod, M; Hai, P T; Sinha, D N; Warren, C W; Jones, N R

    2008-12-01

    The Association of Southeast Asian Nations (ASEAN) has made tobacco use prevention a primary health issue. All ASEAN countries except Indonesia have ratified the World Health Organization Framework Convention on Tobacco Control (WHO FCTC), the world's first public health treaty on tobacco control. Global Youth Tobacco Survey (GYTS) data were collected from representative samples of students in school grades associated with ages 13-15 in Cambodia, Indonesia, Laos (Vientiane), Malaysia, Myanmar, Philippines, Singapore, Thailand and Vietnam (Hanoi). Current cigarette smoking ranged from less than 5% (Vietnam and Cambodia) to 20.2% in Malaysia. Current use of tobacco products other than cigarettes was less than 10% in all countries. Boys were significantly more likely than girls to smoke cigarettes or use other tobacco products. Exposure to second-hand smoke in public places was greater than 50%, direct pro-tobacco advertising exposure was greater than 75% and over 10% of students were exposed to indirect advertising. Over 60% of students who currently smoked cigarettes wanted to stop, but 80% who tried to quit in the year prior to the survey failed. Efforts to reduce the current and projected harm caused by tobacco use in the ASEAN countries are urgently needed. ASEAN countries need to expand their national comprehensive tobacco prevention and control programs and enforce those laws already passed. Without this effort little reduction can be expected in the burden of chronic diseases and tobacco-related mortality.

  14. The Effect of Gender on Sprint Performance of 10-13 Aged Middle School Students

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    Serhat Turan

    2016-04-01

    Full Text Available The aim of the study was to investigate the effect of gender on the 30 m sprint performance of middle school students (10-13 ages. The study included 25 male and 25 female total 50 middle school students. The mean age of female students was found as 12,36 ± 0,48 (year, the mean body weight as 42,03 ± 3,63 (kg, and the mean height as 151,11 ±5,61 (cm, and the mean age of male students was found as 12,28 ± 0,45 (year, the mean height as 152,28 ± 5,04 (cm, and the mean body weight as 43,35 ± 1,88 (kg. The mean sprint performance of female students was calculated as 6,33 ± 0,53 seconds, and the mean sprint performance of the male students was 6,17 ± 0,47 seconds. As a result the effect of gender on sprint performance was found to be insignificant between the groups (p>0,05.

  15. Prevalence and risk factors of anxiety status among students aged 13-26 years

    OpenAIRE

    Jin, Yuelong; He, Lianping; Kang, Yaowen; Chen, Yan; Lu, Wei; Ren, Xiaohua; Song, Xiuli; Wang, Linghong; Nie, Zhonghua; Guo, Daoxia; Yao, Yingshui

    2014-01-01

    Previous study revealed that 8%-12% adolescents suffered from various types of anxiety disorders, and which had interfered with adolescent daily life function and affected adolescent social function. The aim of this study was to evaluate anxiety status and its related factors among students aged 13-26 years from Wuhu, China. This was a cross-sectional observational study. A sample of school students who come from a university, four high schools and four middle schools in Wuhu city were recrui...

  16. Sexual behavior, depressive feelings, and suicidality among Estonian school children aged 13 to 15 years.

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    Heidmets, L; Samm, A; Sisask, M; Kõlves, K; Aasvee, K; Värnik, A

    2010-01-01

    The present paper is based on a WHO Collaborative Cross-National Study "Health Behavior in School-Aged Children (HBSC)." It aimed at describing and analyzing how the sexual behaviors of 13- to 15-year-old Estonian school children were associated with self-reported depressive feelings and suicidality. Distinctive behavioral traits in relation to age of first sexual intercourse were also investigated. Self-reported questionnaires from school children (n = 3,055) were analyzed. In total, 15.2% of school children reported being nonvirgin. Among 13-year-olds, 2.9% of girls and 6.8% of boys were nonvirgins. Approximately 25% of the 15-year-old girls and boys were nonvirgins. The likelihood of depressive feelings and suicidal ideation increased significantly in both genders with loss of virginity. Boys who had lost their virginity at 13 years or younger were 4.2 times more likely to have suicidal thoughts; comparable girls were 7.8 times more likely to have suicidal thoughts. Compared to virgins, youths who had lost their virginity reported poor self-assessed health and more risk behaviors in themselves and their peers. Experiences of sexual intercourse increased the odds ratios for depressive feelings and suicidality. The earlier sexual intercourse was initiated, the greater were the odds of lower mental well-being. Risk behaviors emerged as a complex phenomenon requiring complex prevention.

  17. Students (ages 6, 10, and 15 years in six countries knowledge of animals

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    Patricia Patrick

    2013-04-01

    Full Text Available This article considers the knowledge students (ages 6, 10, and 15 years have of animals from a cross-cultural perspective. Students from six countries (Brazil, England, Finland, Iceland, Portugal, and the United States of America were asked to free-list as many animals as possible and state where they had seen or learned about the animals. The results were analyzed and they indicate that 1 Students are aware of animals. 2 Students are more aware of mammals as examples of animals. 3 There is a globally shared folk biological knowledge of animals. 4 Students learn about animals during sociocultural interactions. The educational implications are discussed.

  18. Phenomena of Inter-age Manipulations in Interaction "Teacher-Student"

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    Miklyaeva A.V.,

    2017-01-01

    Full Text Available Thearticlepresentsthe results of studies of the phenomenon empirical inter-age manipulation in the pedagogical interaction. Inter-age manipulation is considered a form of manipulation carried out on the basis of an appeal to the participants in the interaction age roles. Based on the results of a survey 109 teenagers 13-15 years, using a questionnaire, color test of relations and projective drawing shows that inter-age manipulation is a common way to impact on the students, elected teacher. Teachers are the subjects of inter-age manipulation more often than students. It was revealed that the effectiveness of inter-age manipulation in pedagogical interaction increases if it is meaningful is consistent with the normative content of age roles, as well as «inter-age distance" between the teacher and the students. The greatest effectiveness of have inter-age manipulation undertaken for older teachers, and manipulation "from below" from young teachers

  19. Proficiency Assessment of Male Volleyball Teams of the 13-15-Year Age Group at Estonian Championships

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    Stamm, Meelis; Stamm, Raini; Koskel, Sade

    2008-01-01

    Study aim: Assessment of feasibility of using own computer software "Game" at competitions. Material and methods: The data were collected during Estonian championships in 2006 for male volleyball teams of the 13-15-years age group (n = 8). In all games, the performance of both teams was recorded in parallel with two computers. A total of…

  20. Victimization, Suicidal Ideation, and Alcohol Use From Age 13 to 15 Years: Support for the Self-Medication Model.

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    Marschall-Lévesque, Shawn; Castellanos-Ryan, Natalie; Parent, Sophie; Renaud, Johanne; Vitaro, Frank; Boivin, Michel; Tremblay, Richard E; Séguin, Jean R

    2017-04-01

    Recent years have seen increased coverage of adolescent victimization and suicide. Both adolescent peer victimization and substance use have been associated with suicidal ideation, with evidence suggesting that all three factors are interrelated. There are at least four models which can explain the associations between these factors (i.e., self-medication, secondary mental disorder, bidirectional, and common factor). However, none of them is being empirically supported as the dominant model because few longitudinal studies have explored the association between these factors. The present study compared longitudinal paths of all four models simultaneously using a cross-lagged model. This was done using self-reported measures of peer victimization, suicidal ideation, and alcohol use at age 13, 14, and 15 years in a longitudinal sample of 238 adolescents. All three variables were moderately stable across time. Significant cross-lagged associations were found, showing that frequent peer victimization at age 13 years was associated with higher odds of having suicidal ideation at age 14 years (odds ratio, 1.82; p suicidal ideation at age 14 years was significantly associated with higher alcohol use frequency at age 15 years (β = .13; p suicidal ideation and alcohol use over 1 year, supporting the self-medication model. Clarifying the empirical basis of these underlying models could allow for earlier prevention strategies, by targeting the risk factor that appears the earliest in the model. Copyright © 2016 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  1. Dental health-related behaviour in Scottish schoolchildren aged 11, 13 and 15 from Edinburgh city

    DEFF Research Database (Denmark)

    Currie, C; Schou, L; McQueen, D V

    1989-01-01

    The two most important individually-mediated factors for the control of dental decay and periodontal diseases are frequency of sugar consumption commonly in the form of sweets, and toothbrushing. Most dental health education efforts have therefore been concentrating on informing and motivating...... and social background. Data was collected from 4,890 children aged 11, 13 and 15 years from independent and state schools in Lothian. Subjects completed a questionnaire, anonymously, in class....

  2. [Indicators of general, cerebral, and regional hemodynamics in myopic schoolchildren aged 13-15 years].

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    Iastrebtseva, T A; Chuprov, A D; Plotnikova, Iu A

    2002-01-01

    110 schoolchildren aged 13-15 years were examined. 24 of them had pseudomyopia and 6 patients myopia of various forms. A control group consisted of 38 children. Central hemodynamics was estimated by average dynamic pressure, cerebral hemodynamics--by rheoencephalography, regional hemodynamics--by dopplerography of the internal carotid and suprapubic arteries. It was found that with myopia progression, the average dynamic pressure positively comes down with reduction of reographic waves amplitude in rheogram. The blood flow rate in internal carotid and suprapubic arteries has no substantial impact on myopia course. Predisposition to arterial hypotension is a risk factor for myopia development and progression.

  3. [Body mass, self-esteem and life satisfaction in adolescents aged 13-15 years].

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    Tabak, Izabela; Mazur, Joanna; Oblacińska, Anna; Jodkowska, Maria

    2007-01-01

    The aim of the study was to analyse the relationships between objective body mass index and subjective body image, life satisfaction and self-esteem of adolescents. the study was carried in 5 regions in Poland, on the sample of over 8,000 pupils aged 13-15 yrs, from randomly chosen 112 lower secondary schools. School nurses measured the height and weight of pupils, calculated the BMI and qualified overweight pupils (BMI> or =85 percentile) to the obese group (n = 953). Matching gender and age, from the rest of pupils, they found the non-obese group with BMI between 15 and 75 percentile (n = 953). Pupils from both groups participated in a questionnaire study containing the Rosenberg Self-Esteem Scale, Cantril ladder and Stunkard Body Figure Perception Questionnaire. Hierarchic regression analyses and structural equation models were calculated. in the obese group the percentage of pupils satisfied with their life was lower (76% vs 82%, pself-esteem higher than in the non-obese (37% vs 23%, plife satisfaction and self-esteem was subjective body image, and not the objective body mass index. Objective body mass (BMI) determined the body image and relationship between BMI and life satisfaction or self-esteem of adolescents was only indirect. change of subjective body image in obese adolescents is a chance for improving their quality of life and in consequence undertaking effective struggle with obesity.

  4. Leisure Time Physical Inactivity and Sedentary Behaviour and Lifestyle Correlates among Students Aged 13-15 in the Association of Southeast Asian Nations (ASEAN) Member States, 2007-2013.

    Science.gov (United States)

    Peltzer, Karl; Pengpid, Supa

    2016-02-15

    The aim of this study was to examine the relationship between self-reported leisure time physical inactivity frequency and sedentary behaviour and lifestyle correlates among school children in the Association of Southeast Asian Nations (ASEAN) region. The analysis included 30,284 school children aged 13-15 years from seven ASEAN countries that participated in the Global School-based Student Health Survey (GSHS) between 2007 and 2013. The measure asked about overall physical activity, walking or biking to school, and on time spent sitting. Overall, the prevalence of physical inactivity was 80.4%, ranging from 74.8% in Myanmar to 90.7% in Cambodia and sedentary behaviour 33.0%, ranging from 10.5% in Cambodia and Myanmar to 42.7% in Malaysia. In multivariate logistic regression, not walking or biking to school, not attending physical education classes, inadequate vegetable consumption and lack of protective factors (peer and parental or guardian support) were associated with physical inactivity, and older age (14 and 15 years old), coming from an upper middle income country, being overweight or obese, attending physical education classes, alcohol use, loneliness, peer support and lack of parental or guardian supervision were associated with sedentary behaviour. In boys, lower socioeconomic status (in the form of having experienced hunger) and coming from a low income or lower middle income country were additionally associated with physical inactivity, and in girls, higher socioeconomic status, not walking or biking to school and being bullied were additionally associated with sedentary behaviour. In conclusion, a very high prevalence of leisure physical inactivity and sedentary behaviour among school going adolescents in ASEAN was found and several factors identified that may inform physical activity promotion programmes in school-going adolescents in ASEAN.

  5. Students' unchanging smoking habits in urban and rural areas in the last 15 years.

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    Akca, Gulfer; Guner, Sukru Nail; Akca, Unal; Kilic, Mehtap; Sancak, Recep; Ozturk, Fadil

    2016-04-01

    Smoking is the main preventable public health problem particularly for youth worldwide. The aim of the present study was to determine the prevalence of smoking habits among students at secondary and high schools, and to compare the findings with those of a study conducted 15 years ago in the same area. In this cross-sectional study 6212 students (51.2% female; 48.8% male) were selected randomly from rural and urban areas in Samsun. All students completed a face-to-face questionnaire. The overall prevalence of smoking was 13.0% (male students, 18.1%; female students, 8.2%). The mean starting age of smoking was 14.1 ± 1.5 years. Prevalence of smoking was 15.7% in urban areas and 8.1% in rural areas. The most important factors for starting smoking were social group and families. Compared with a study conducted 15 years previously in the same area for male students, smoking prevalence was increased in rural, but decreased in urban areas. Smoking prevalence in students in Samsun was similar to that in a study conducted 15 years previously. It is important to use anti-smoking campaigns directly targeted at teenager and they should be fully informed of the harmful effects of smoking. © 2015 Japan Pediatric Society.

  6. Assessing Outgroup Prejudice among 13-15-Year-Old Students Attending Catholic and Protestant Secondary Schools in Northern Ireland: An Empirical Enquiry

    Science.gov (United States)

    Francis, Leslie J.; Village, Andrew

    2015-01-01

    Northern Ireland has been and remains a religiously divided community. This study sets out to examine outgroup prejudice among a sample of 1799 13-15-year-old students attending Catholic or Protestant schools and employs both bivariate analyses and hierarchical modelling to chart the associations between outgroup prejudice and personal factors…

  7. Leisure Time Physical Inactivity and Sedentary Behaviour and Lifestyle Correlates among Students Aged 1315 in the Association of Southeast Asian Nations (ASEAN) Member States, 2007–2013

    Science.gov (United States)

    Peltzer, Karl; Pengpid, Supa

    2016-01-01

    The aim of this study was to examine the relationship between self-reported leisure time physical inactivity frequency and sedentary behaviour and lifestyle correlates among school children in the Association of Southeast Asian Nations (ASEAN) region. The analysis included 30,284 school children aged 1315 years from seven ASEAN countries that participated in the Global School-based Student Health Survey (GSHS) between 2007 and 2013. The measure asked about overall physical activity, walking or biking to school, and on time spent sitting. Overall, the prevalence of physical inactivity was 80.4%, ranging from 74.8% in Myanmar to 90.7% in Cambodia and sedentary behaviour 33.0%, ranging from 10.5% in Cambodia and Myanmar to 42.7% in Malaysia. In multivariate logistic regression, not walking or biking to school, not attending physical education classes, inadequate vegetable consumption and lack of protective factors (peer and parental or guardian support) were associated with physical inactivity, and older age (14 and 15 years old), coming from an upper middle income country, being overweight or obese, attending physical education classes, alcohol use, loneliness, peer support and lack of parental or guardian supervision were associated with sedentary behaviour. In boys, lower socioeconomic status (in the form of having experienced hunger) and coming from a low income or lower middle income country were additionally associated with physical inactivity, and in girls, higher socioeconomic status, not walking or biking to school and being bullied were additionally associated with sedentary behaviour. In conclusion, a very high prevalence of leisure physical inactivity and sedentary behaviour among school going adolescents in ASEAN was found and several factors identified that may inform physical activity promotion programmes in school-going adolescents in ASEAN. PMID:26891312

  8. Leisure Time Physical Inactivity and Sedentary Behaviour and Lifestyle Correlates among Students Aged 1315 in the Association of Southeast Asian Nations (ASEAN Member States, 2007–2013

    Directory of Open Access Journals (Sweden)

    Karl Peltzer

    2016-02-01

    Full Text Available The aim of this study was to examine the relationship between self-reported leisure time physical inactivity frequency and sedentary behaviour and lifestyle correlates among school children in the Association of Southeast Asian Nations (ASEAN region. The analysis included 30,284 school children aged 1315 years from seven ASEAN countries that participated in the Global School-based Student Health Survey (GSHS between 2007 and 2013. The measure asked about overall physical activity, walking or biking to school, and on time spent sitting. Overall, the prevalence of physical inactivity was 80.4%, ranging from 74.8% in Myanmar to 90.7% in Cambodia and sedentary behaviour 33.0%, ranging from 10.5% in Cambodia and Myanmar to 42.7% in Malaysia. In multivariate logistic regression, not walking or biking to school, not attending physical education classes, inadequate vegetable consumption and lack of protective factors (peer and parental or guardian support were associated with physical inactivity, and older age (14 and 15 years old, coming from an upper middle income country, being overweight or obese, attending physical education classes, alcohol use, loneliness, peer support and lack of parental or guardian supervision were associated with sedentary behaviour. In boys, lower socioeconomic status (in the form of having experienced hunger and coming from a low income or lower middle income country were additionally associated with physical inactivity, and in girls, higher socioeconomic status, not walking or biking to school and being bullied were additionally associated with sedentary behaviour. In conclusion, a very high prevalence of leisure physical inactivity and sedentary behaviour among school going adolescents in ASEAN was found and several factors identified that may inform physical activity promotion programmes in school-going adolescents in ASEAN.

  9. 40 CFR 13.15 - Taxpayer information.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Taxpayer information. 13.15 Section 13.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL CLAIMS COLLECTION STANDARDS Collection § 13.15 Taxpayer information. (a) The Administrator may obtain a debtor's current mailing address...

  10. 47 CFR 15.13 - Incidental radiators.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Incidental radiators. 15.13 Section 15.13 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL RADIO FREQUENCY DEVICES General § 15.13 Incidental radiators. Manufacturers of these devices shall employ good engineering practices to minimize the risk of...

  11. Bullying victimization among 13 til 15 year old school children

    DEFF Research Database (Denmark)

    Due, Pernille; Holstein, Bjørn Evald

    2008-01-01

    AIM: to examine the prevalence of bullying victimization in 66 countries and territories from five continents based on data from two large international surveys: the 2001/2 Health Behavior in School-aged Children survey (HBSC) and the Global School-based Students Health Survey (GSHS). The surveys...... provide nationally representative, cross-sectional information on 13-15-year-old school children (N = 218,104). OUTCOME MEASURES: Bullying victimization, once or more within the past 2 months (HBSC)/30 days (GSHS). RESULTS: On average, 32.1% of the children were bullied at school at least once within...... the past 2 months in countries involved in the HBSC study and 37.4% of children were bullied at least one day within the past 30 days in countries involved in the GSHS study. In both surveys, a large variation in prevalence was found across countries. The lowest prevalence in the GSHS survey was observed...

  12. Correlation between breakfast tryptophan content and morning-evening in Japanese infants and students aged 0-15 yrs.

    Science.gov (United States)

    Harada, Tetsuo; Hirotani, Masaaki; Maeda, Mari; Nomura, Hiromi; Takeuchi, Hitomi

    2007-03-01

    Tryptophan can be metabolized via 5-hydroxytryptamine=serotonin to melatonin by a series of 4 enzymes in pineal body. Lack of serotonin in body fluid in the brain during daytime can lead to several psychiatric disorders, while shortage of plasma-melatonin at night can be related to sleep disorders. The Morning-Evening (M-E) questionnaire and the original questionnaire including questions on sleep habits, mental symptoms, and contents of meals were administered to 1055 infants aged 0-6 yrs, 751 students attending an elementary school, and 473 students attending junior high school in Kochi City (33 degrees N). The index of tryptophan taken at breakfast (Trp-Index) was calculated as tryptophan amount per one meal based on the tryptophan included in each 100 g of the foods and a standard amount of food per one meal. A significant positive-correlation between M-E scores and Trp-Index was not shown by relatively older students, aged 9-15 yrs (Pearson's test, r=0.044-0.123, p=0.071-0.505), whereas a significant positive correlation was shown by infants and young elementary school students aged 0-8 yrs (r=0.180, 0.258, phigh quality of sleep, and indirectly good mental health, presumably, through the metabolism of tryptophan to serotonin in daytime and further to melatonin at night.

  13. Knowledge, attitude and behavioral determinants of tobacco use among 13-15 year old school children.

    Science.gov (United States)

    Raina, Romshi; Krishna, Madhusudan; Murali, R; Shamala, A; Yalamalli, Maanasi; Kumar, A Vinod

    2015-01-01

    The epidemic of tobacco use is one of the greatest threats to global health today. Tobacco attributable deaths in India currently range from 800,000 to 900,000 per year. Adolescents are among the most vulnerable group to start tobacco use. Information on tobacco use among the youth is necessary to establish control measures against it. To assess the knowledge, attitude, and behavioral determinants of tobacco use among high school students (age13-15 years) in Bangalore. A cross-sectional study was conducted over a period of 3 weeks in the month of September 2012. A structured, pretested questionnaire was administered randomly to 500 high school students in Bangalore to assess the knowledge, attitude, and behavioral determinants of tobacco use. Majority of the study population [94.4% (472/500)] believed that smoking is definitely harmful to our health. Also, 39.0% of the participants of age 13 years believed that smoking does not help in socializing and 92.2% of study subjects had negative attitude toward starting the habit. Most of them (83.9%) had a negative perception about smokers that they lack confidence. However, less than 1% of the study population had a habit of smoking at this young age. Awareness of the harmful effects of smoking was high among the study population. The study provides insight into the factors to consider while planning adolescent anti-smoking programs in this and similar settings.

  14. 15 CFR 806.13 - Miscellaneous.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Miscellaneous. 806.13 Section 806.13 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF ECONOMIC ANALYSIS, DEPARTMENT OF COMMERCE DIRECT INVESTMENT SURVEYS § 806.13 Miscellaneous. (a) Accounting...

  15. 43 CFR 15.13 - Report of accidents.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Report of accidents. 15.13 Section 15.13 Public Lands: Interior Office of the Secretary of the Interior KEY LARGO CORAL REEF PRESERVE § 15.13 Report of accidents. Accidents involving injury to life or property shall be reported as soon as possible...

  16. 6 CFR 13.15 - Ex parte contacts.

    Science.gov (United States)

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Ex parte contacts. 13.15 Section 13.15 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.15 Ex parte contacts. No party or Person (except employees of the ALJ's office) will communicate in any way...

  17. Fast food and obesity: a spatial analysis in a large United Kingdom population of children aged 13-15.

    Science.gov (United States)

    Fraser, Lorna K; Clarke, Graham P; Cade, Janet E; Edwards, Kimberly L

    2012-05-01

    The childhood obesity epidemic is a current public health priority in many countries, and the consumption of fast food has been associated with obesity. This study aims to assess the relationship between fast-food consumption and obesity as well as the relationship between fast-food outlet access and consumption in a cohort of United Kingdom teenagers. A weighted accessibility score of the number of fast-food outlets within a 1-km network buffer of the participant's residence at age 13 years was calculated. Geographically weighted regression was used to assess the relationships between fast-food consumption at age 13 years and weight status at ages 13 and 15 years, and separately between fast-food accessibility and consumption. Data were collected from 2004 to 2008. The consumption of fast food was associated with a higher BMI SD score (β=0.08, 95% CI=0.03, 0.14); higher body fat percentage (β=2.06, 95% CI=1.33, 2.79); and increased odds of being obese (OR=1.23, 95% CI=1.02, 1.49). All these relationships were stationary and did not vary over space in the study area. The relationship between the accessibility of outlets and consumption did vary over space, with some areas (more rural areas) showing that increased accessibility was associated with consumption, whereas in some urban areas increased accessibility was associated with lack of consumption. There is continued need for nutritional education regarding fast food, but public health interventions that place restrictions on the location of fast-food outlets may not uniformly decrease consumption. Copyright © 2012 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  18. [Validity and reproducibility of an Internet-based questionnaire (Web-CAAFE) to evaluate the food consumption of students aged 7 to 15 years].

    Science.gov (United States)

    Jesus, Gilmar Mercês de; Assis, Maria Alice Altenburg de; Kupek, Emil

    2017-06-05

    The study evaluated the validity and reproducibility of the food consumption section of the questionnaire Food Intake and Physical Activity of School Children (Web-CAAFE), an Internet-based software for the qualitative measurement of food consumption by recalling the previous day. A total of 390 students in grades 2 to 5 (7 to 15 years) of a semi-integral public school participated in the study. The validity was tested by comparing the report in the Web-CAAFE and the direct observation of food consumed in the school in the previous day. The reproducibility was evaluated in a sub-sample of 92 schoolchildren, by comparing repeated reports in the Web-CAAFE on the same day. Probabilities of accuracy in the Web-CAAFE report in relation to the observation (matches, omissions and intrusions and respective 95% confidence intervals) among seven food groups were estimated through multinomial logistic regression. The average for the match rate was 81.4% (variation: 62% sweets and 98% beans); for the omission rate was 16.2% (variation between 2.1% dairy products and 28.5% sweets); for the intrusion rate was 7.1% (variation between 1.3% beans and 13.8% cereals). Sweets, cereals and processed foods, snack foods and fried foods simultaneously exhibited higher rates of omission and intrusion. Students 10 years of age or older had lower probabilities of intruding food items. There were no significant variations in the accuracy of the report between repeated measures. The Web-CAAFE was a valid and reliable instrument for the evaluation of food consumption, when applied to students in grades 2 to 5 of public schools.

  19. 15 CFR 303.13 - Appeals.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Appeals. 303.13 Section 303.13 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) INTERNATIONAL... and two copies with the U.S. Department of Commerce, Import Administration, International Trade...

  20. 44 CFR 15.13 - Dogs and other animals.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Dogs and other animals. 15.13 Section 15.13 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF... EMERGENCY TRAINING CENTER § 15.13 Dogs and other animals. Dogs and other animals, except seeing-eye dogs...

  1. 46 CFR 12.15-13 - Deck engine mechanic.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Deck engine mechanic. 12.15-13 Section 12.15-13 Shipping... ENDORSEMENTS Qualified Member of the Engine Department § 12.15-13 Deck engine mechanic. (a) An applicant for an endorsement as deck engine mechanic shall be a person holding an MMC or MMD endorsed as junior engineer. The...

  2. Unbiased ascertainment of a patient with a 47,XY, +pseudic (15)t(15;15)(q13;q13) karyotype by amniocentesis

    Energy Technology Data Exchange (ETDEWEB)

    Spector, E.; Prochazka, G.; Hamilton, S. [Univ. of Colorado School of Medicine, Denver (United States)] [and others

    1994-09-01

    A 47,XY,+mar male karyotype was found in all metaphases on an amniocentesis from a 36-year-old woman (G1,P0). The marker was G group size. Chromosome studies on the parents were normal. C-banding, NOR staining and FISH demonstrated that the marker was dicentric, bisatellited, derived from No. 15 and contained 2 copies of the chromosomal region flanked by the Prader-Willi/Angelman A and B probes. The final karyotype was: 47,XY,+pseudic(15)t(15;15)(q13;q13), making the fetus tetrasomic for the genes in the duplicated region. DNA marker studies for No. 15 (performed in the laboratory of Dr. David Ledbetter) revealed that the fetus had inherited on No. 15 from each parent and that the marker was derived from both maternal No. 15 chromosomes. The parents chose to continue the pregnancy. The baby was born at 38 weeks gestation, was mildly edematous and had Apgar scores of 4, 7, and 8 at 1, 5, and 10 min, respectively. The marker was confirmed to be present in placenta and the baby`s blood. Examination at 6 weeks showed appropriate growth and development. Data from published cases predict that this baby will be mentally retarded and may have seizures because he is tetrasomic for 15pter-q13, but will not have Prader-Willi or Angelman syndromes since he has biparental inheritance of his normal No. 15s. However, the published cases may represent a biased sample as most were identified in mentally retarded individuals, not by prenatal diagnosis. This infant`s development will continue to be followed closely.

  3. Attitudes to HPV Vaccination among Parents of Children Aged 10 to 13 Years.

    Science.gov (United States)

    Seven, Memnun; Güvenç, Gülten; Şahin, Eda; Akyüz, Aygül

    2015-10-01

    This study aimed to determine the willingness of parents to allow their sons and/or daughters aged 10-13 years to be vaccinated for human papillomavirus (HPV). This was a descriptive study conducted in an elementary school to recruit students' parents into the study. The sample consisted of 368 (69.1%) parents of children aged 10-13 years who were willing to participate in the study as a couple. Questionnaire-based data were collected from the couples. Prior information regarding HPV and vaccination and the opinions of parents of children aged 10-13 about HPV vaccination for their daughter or son. Only 26.9% of mothers and 25.0% of fathers claimed to be aware of HPV, and only 24.5% of mothers and 21.2% of fathers claimed to be aware of its vaccine. If the vaccine were available in Turkey, 21.6% of mothers and 22.4% of fathers would be willing to vaccinate their sons; although the vaccine for girls is available in Turkey, only 14.4% of mothers and 15.5% of fathers were willing to vaccinate their daughters. Few participants reported knowing about the HPV vaccine, while far fewer intended to vaccinate their daughters and sons against the infection. Both males and females should be informed about HPV and its vaccine, and initiatives to increase both awareness and the information of health care professionals should be encouraged. Copyright © 2015 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

  4. The Impact of Age on Using Language Learning Strategies

    Science.gov (United States)

    Sepasdar, Mansoreh; Soori, Afshin

    2014-01-01

    Since age plays an important role in learning a second or foreign language, the present study investigated how different students in different age groups used language learning strategies. The participants of this study were 94 Iranian EFL students from four educational levels and different age groups as, primary (10-12), guidance (13-15), high…

  5. 15 CFR 15.13 - Demand for testimony or production of documents: Department policy.

    Science.gov (United States)

    2010-01-01

    ...; (d) To avoid spending the time and money of the United States for private purposes; (e) To preserve... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Demand for testimony or production of documents: Department policy. 15.13 Section 15.13 Commerce and Foreign Trade Office of the Secretary of...

  6. Diet-tissue stable isotope (Δ(13)C and Δ(15)N) discrimination factors for multiple tissues from terrestrial reptiles.

    Science.gov (United States)

    Steinitz, Ronnie; Lemm, Jeffrey M; Pasachnik, Stesha A; Kurle, Carolyn M

    2016-01-15

    Stable isotope analysis is a powerful tool for reconstructing trophic interactions to better understand drivers of community ecology. Taxon-specific stable isotope discrimination factors contribute to the best use of this tool. We determined the first Δ(13)C and Δ(15)N values for Rock Iguanas (Cyclura spp.) to better understand isotopic fractionation and estimate wild reptile foraging ecology. The Δ(13)C and Δ(15)N values between diet and skin, blood, and scat were determined from juvenile and adult iguanas held for 1 year on a known diet. We measured relationships between iguana discrimination factors and size/age and quantified effects of lipid extraction and acid treatment on stable isotope values from iguana tissues. Isotopic and elemental compositions were determined by Dumas combustion using an elemental analyzer coupled to an isotope ratio mass spectrometer using standards of known composition. The Δ(13)C and Δ(15)N values ranged from -2.5 to +6.5‰ and +2.2 to +7.5‰, respectively, with some differences among tissues and between juveniles and adults. The Δ(13)C values from blood and skin differed among species, but not the Δ(15)N values. The Δ(13)C values from blood and skin and Δ(15)N values from blood were positively correlated with size/age. The Δ(13)C values from scat were negatively correlated with size (not age). Treatment with HCl (scat) and lipid extraction (skin) did not affect the isotope values. These results should aid in the understanding of processes driving stable carbon and nitrogen isotope discrimination factors in reptiles. We provide estimates of Δ(13)C and Δ(15)N values and linear relationships between iguana size/age and discrimination factors for the best interpretation of wild reptile foraging ecology. Copyright © 2015 John Wiley & Sons, Ltd.

  7. 15 CFR 785.13 - Procedural stipulations.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Procedural stipulations. 785.13 Section 785.13 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL PROTOCOL REGULATIONS ENFORCEMENT § 785...

  8. 15 CFR 90.13 - Offer of hearing.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Offer of hearing. 90.13 Section 90.13 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE PROCEDURE FOR CHALLENGING CERTAIN POPULATION AND INCOME ESTIMATES § 90.13 Offer of...

  9. 13 CFR 315.15 - Conflicts of interest.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Conflicts of interest. 315.15 Section 315.15 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF COMMERCE TRADE ADJUSTMENT ASSISTANCE FOR FIRMS Protective Provisions § 315.15 Conflicts of interest. EDA will...

  10. Preparation of 15N-13C-fulminic acid

    International Nuclear Information System (INIS)

    Wilmes, R.; Winnewisser, M.

    1993-01-01

    The precursor for the title compound was prepared in a three-step synthesis. The 13 C-label was incorporated in the first step employing 2- 13 C-ethyl acetate and the 15 N-label in the last step, using 15 N-sodium nitrite. Upon pyrolysis the precursor forms three fragments, one of them being the title compound. (Author)

  11. Reading for 11-13-Year-Old Students in the Digital Age: New Zealand Case Studies

    Science.gov (United States)

    Fletcher, Jo; Nicholas, Karen

    2018-01-01

    ABSTRACT In New Zealand schools, the focus continues to be on improving the reading achievement of all students situated across a range of socio-economic groups. This is particularly so for our young adolescent students, where research investigations have indicated some concerning trends which influence reading development for this age group. This…

  12. 15 CFR 325.13 - Nonadmissibility in evidence.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Nonadmissibility in evidence. 325.13 Section 325.13 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE MISCELLANEOUS REGULATIONS EXPORT TRADE CERTIFICATES...

  13. Differences in motor skills of pupils aged 13 measured in 1970 and 1995

    Directory of Open Access Journals (Sweden)

    Stojanović Darko

    2013-01-01

    Full Text Available Body fat percentage is higher in relation to muscle in reduced physical activity, which significantly affects the level of motorabilities of students. The results of previously conducted research in the area of motor skills quickly become obsolete. During school age tracking students growth and development enables us to assess the regularity of the developmental period. By measuring the motor dimensions we come to some data about their development. If we want to get to the question of whether there is a change in the development of motor skills, it is necessary to compare their development with the development of students the same age measured more than twenty years. The aim of this study was to determine the difference of motor abilities of the pupils aged 13 years measured in 1970 and 1995 year. Measurement of motor skills are performed according to the methodology that was applied by Kurelić et al. (1975. Determination of differences was done by Difference test from the statistical package Statistica 8.0 for Windows, compared to the availabledata of means and standard deviations of respondents. The results of this research indicate that students which are measured in 1970 had better motor skills compared to students of the same age measured in 1995, except in test foot taping (MTAN.

  14. 15 CFR 14.13 - Debarment and suspension.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Debarment and suspension. 14.13 Section 14.13 Commerce and Foreign Trade Office of the Secretary of Commerce UNIFORM ADMINISTRATIVE... shall comply with the nonprocurement debarment and suspension common rule implementing E.O.s 12549 and...

  15. 15 CFR 2008.13 - Systematic review guidelines.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Systematic review guidelines. 2008.13 Section 2008.13 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS TO IMPLEMENT E.O. 12065; OFFICE OF THE UNITED STATES TRADE...

  16. Body dissatisfaction and self-esteem in female students aged 9-15: the effects of age, family income, body mass index levels and dance practice.

    Science.gov (United States)

    Monteiro, Lilian A; Novaes, Jefferson S; Santos, Mara L; Fernandes, Helder M

    2014-09-29

    This study aimed to analyze the effects of age, family income, body mass index and dance practice on levels of body dissatisfaction and self-esteem in female students. The sample consisted of 283 female subjects attending a public school with a mean age of 11.51±1.60 years and a mean body mass index of 18.72 kg/m2 (SD=3.32). The instruments used were the Body Dissatisfaction Scale for Adolescents and the Rosenberg Self-Esteem Scale, both of which showed good internal consistency (0.77 and 0.81, respectively). The tests were applied (two-factor ANOVA) to compare the students practicing and those not practicing dance; the differences in the levels of body dissatisfaction (p=0.104) and self-esteem (p=0.09) were considered significant. The results demonstrated that age negatively correlated with body dissatisfaction (r=-0.19; pbody mass index levels were associated with greater body dissatisfaction (r=0.15, p=0.016) and lower levels of self-esteem (r=-0.17, pbody dissatisfaction (F=4.79; p=0.030; η(2)=0.02), but there was no significant difference in self-esteem (F=1.88; p=0.172; η(2)=0.02). It can be concluded that female children and adolescents practicing dance have higher self-esteem, and are more satisfied with their body weight and their appearance. Moreover, results showed that self-esteem and body dissatisfaction were influenced by the body mass index levels only in the non-practitioners group.

  17. Manejo de novilhas prenhes aos 13/15 meses de idade em sistemas a pasto Pregnant heifers management at 13/15 months of age in grazing systems

    Directory of Open Access Journals (Sweden)

    Alcides Pilau

    2008-07-01

    de vaca.This experiment was carried out to evaluate the development of 32 primiparous beef heifers Aberdeen Angus and Angus crossbred raised and mating from 13 to the 15 months of age. The experiment had beginning in the pregnancy diagnosis of using ultra-sound technique, realized at 28 days after the ending of the reproductive period. The initial average weight and body condition (BC was 288 kg LW and 3.2 points, respectively. In this occasion, the beef heifers were uniformly distributed by genetic group, LW and conception order in two grazing systems. Grazing systems were: PMI - pregnant beef heifers maintained in the initial pregnancy period on pearl millet pasture (Pennisetum americanum, L.; PNA - pregnant heifers maintained in the initial pregnancy period on natural pasture. Grazed period was 67 days in pearl millet pasture. At end of the treatments the beef heifers were maintained as a unique group: on natural pasture at pre calving period, on annual ryegrass (Lolium multiflorum, Lam pasture at post calving period and on natural pasture at second reproductive period. In the initial pregnancy phase, the average daily gain (ADG of 0.899 kg and body condition gain (BCG, 0.34 points of the PMI heifers were higher then the ADG of 0.377 kg and BC lost of -0.15 for PNA heifers. The PMI beef heifers had post calving live weight (PCW and post calving body condition of 301 kg and 2.9 points, respectively, higher values than of PNA beef heifers, 267 kg and 2.7 points. Calving, dystocia, birth and weaning rates were not different between the feeding treatment. The PMI beef heifers were 31 kg heaviest and with more 0.30 point of BC at initial second reproductive period. The pregnancy rate (PR and estimations of calving productive efficiency (CPEE and weaning productive efficiency at 100 days of age (WPEE were not different between feeding treatments. Mean PR was 77%. Mean CPEE was 30.3 and WPEE 28.1 kg of weaning calf/100 kg of cow.

  18. Human parechovirus genotypes -10, -13 and -15 in Pakistani children with acute dehydrating gastroenteritis.

    Directory of Open Access Journals (Sweden)

    Muhammad Masroor Alam

    Full Text Available Human parechoviruses are known to cause asymptomatic to severe clinical illness predominantly respiratory and gastroenetric infections. Despite their global prevalence, epidemiological studies have not been performed in Pakistan. In this study, we retrospectively analyzed 110 fecal specimen and found 26 (24% positive for viral RNA with HPeV-10 (n = 3, 23%, HPeV-13 (n = 4, 31% and HPeV-15 (n = 6, 46% genotypes. Clinical features of patients with different HPeV genotypes were compared. All HPeV positive children were aged ≤4 years (mean 13.92 months. The male-to-female ratio was 1: 1.17 (46.2 vs 53.8% with significant association (p = .031 to HPeV infectivity. HPeV-10 and -13 were found during summer while HPeV-15 was only detected during late winter season. Disease symptoms were more severe in children infected with HPeV-10 and -13 as compared to HPeV-15. Fever and vomiting were observed in 100% cases of HPeV-10 and -13 while only 17% patients of HPeV-15 had these complaints. Phylogenetic analyses showed that HPeV-10, -13 and -15 strains found in this study have 9-13%, 16.8% and 21.8% nucleotide divergence respectively from the prototype strains and were clustered to distinct genetic lineages. This is the first report of HPeV-15 infection in humans although first identified in rhesus macaques. The arginine-glycine-aspartic acid (RGD motif present at the C-terminal of VP1 responsible for the viral attachment to cellular integrins was not found in all of these strains. In conclusion, these findings enhance our knowledge related to the epidemiology and genetic diversity of the HPeV in Pakistan and support the need for continued laboratory based surveillance programs especially in infants and neonatal clinical settings. Further, the parechovirus pathogenesis, cross-species transmission and disease reservoirs must be ascertained to adopt better prevention measures.

  19. Impact of an Aging Simulation Game on Pharmacy Students' Empathy for Older Adults.

    Science.gov (United States)

    Chen, Aleda M H; Kiersma, Mary E; Yehle, Karen S; Plake, Kimberly S

    2015-06-25

    To evaluate changes in empathy and perceptions as well as game experiences among student pharmacists participating in an aging simulation game. First-year student pharmacists participated in an aging simulation game. Changes were measured pre/post-activity using the Kiersma-Chen Empathy Scale (KCES) and Jefferson Scale of Empathy--Health Professions Scale (JSE-HPS) for empathy and the Aging Simulation Experience Survey (ASES) for perceptions of older adults' experiences and game experiences. Wilcoxon signed rank tests were used to determine changes. One hundred fifty-six student pharmacists completed the instruments. Empathy using the KCES and JSE-HPS improved significantly. Of the 13 items in the ASES, 9 significantly improved. Simulation games may help students overcome challenges demonstrating empathy and positive attitudes toward elderly patients.

  20. Body Dissatisfaction and Self-Esteem in Female Students Aged 9-15: the Effects of Age, Family Income, Body Mass Index Levels and Dance Practice

    Directory of Open Access Journals (Sweden)

    Monteiro Lilian A.

    2014-12-01

    Full Text Available This study aimed to analyze the effects of age, family income, body mass index and dance practice on levels of body dissatisfaction and self-esteem in female students. The sample consisted of 283 female subjects attending a public school with a mean age of 11.51±1.60 years and a mean body mass index of 18.72 kg/m2 (SD=3.32. The instruments used were the Body Dissatisfaction Scale for Adolescents and the Rosenberg Self-Esteem Scale, both of which showed good internal consistency (0.77 and 0.81, respectively. The tests were applied (two-factor ANOVA to compare the students practicing and those not practicing dance; the differences in the levels of body dissatisfaction (p=0.104 and self-esteem (p=0.09 were considered significant. The results demonstrated that age negatively correlated with body dissatisfaction (r=-0.19; p<0.01 and that higher body mass index levels were associated with greater body dissatisfaction (r=0.15, p=0.016 and lower levels of self-esteem (r=-0.17, p<0.01 only in non-practitioners. The practice of dance had a significant effect on levels of body dissatisfaction (F=4.79; p=0.030; η2=0.02, but there was no significant difference in self-esteem (F=1.88; p=0.172; η2=0.02. It can be concluded that female children and adolescents practicing dance have higher self-esteem, and are more satisfied with their body weight and their appearance. Moreover, results showed that self-esteem and body dissatisfaction were influenced by the body mass index levels only in the nonpractitioners group.

  1. Biosynthesis of quinolizidine alkaloids. Incorporation of [1-amino-15N, 1-13C] cadaverine into lupanine, 13-hydroxylupanine, and angustifoline

    International Nuclear Information System (INIS)

    Rana, J.; Robins, D.J.

    1985-01-01

    The labelling patterns in (+)-lupanine, (+)-13-hydroxylupanine, and (+)-angustifoline derived biosynthetically from [1-amino- 15 N,1- 13 C]-1,5-diaminopentane (cadaverine) have been established by 13 C n.m.r. spectroscopy. Three cadaverine units are incorporated to about the same extent into each of these three alkaloids. The presence of two doublets due to 13 C- 15 N coupling in the 13 C brace 1 H brace n.m.r. spectra associated with C-2 and C-15 of lupanine and 13-hydroxylupanine, and one 13 C- 15 N doublet at C-2 of angustifoline, indicate that two of the cadaverine units are converted into the outer rings of the tetracyclic quinolizidine alkaloids in a specific fashion. (author)

  2. Application of unsymmetrical indirect covariance NMR methods to the computation of the (13)C (15)N HSQC-IMPEACH and (13)C (15)N HMBC-IMPEACH correlation spectra.

    Science.gov (United States)

    Martin, Gary E; Hilton, Bruce D; Irish, Patrick A; Blinov, Kirill A; Williams, Antony J

    2007-10-01

    Utilization of long-range (1)H--(15)N heteronuclear chemical shift correlation has continually grown in importance since the first applications were reported in 1995. More recently, indirect covariance NMR methods have been introduced followed by the development of unsymmetrical indirect covariance processing methods. The latter technique has been shown to allow the calculation of hyphenated 2D NMR data matrices from more readily acquired nonhyphenated 2D NMR spectra. We recently reported the use of unsymmetrical indirect covariance processing to combine (1)H--(13)C GHSQC and (1)H--(15)N GHMBC long-range spectra to yield a (13)C--(15)N HSQC-HMBC chemical shift correlation spectrum that could not be acquired in a reasonable period of time without resorting to (15)N-labeled molecules. We now report the unsymmetrical indirect covariance processing of (1)H--(13)C GHMBC and (1)H--(15)N IMPEACH spectra to afford a (13)C--(15)N HMBC-IMPEACH spectrum that has the potential to span as many as six to eight bonds. Correlations for carbon resonances long-range coupled to a protonated carbon in the (1)H--(13)C HMBC spectrum are transferred via the long-range (1)H--(15)N coupling pathway in the (1)H--(15)N IMPEACH spectrum to afford a much broader range of correlation possibilities in the (13)C--(15)N HMBC-IMPEACH correlation spectrum. The indole alkaloid vincamine is used as a model compound to illustrate the application of the method. (c) 2007 John Wiley & Sons, Ltd.

  3. 13 CFR 115.15 - Underwriting and servicing standards.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Underwriting and servicing standards. 115.15 Section 115.15 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SURETY BOND... underwriting and the Surety's principles and practices on unguaranteed bonds. The Principal must satisfy the...

  4. Prader-Willi Syndrome due to an Unbalanced de novo Translocation t(15;19)(q12;p13.3).

    Science.gov (United States)

    Dang, Vy; Surampalli, Abhilasha; Manzardo, Ann M; Youn, Stephanie; Butler, Merlin G; Gold, June-Anne; Kimonis, Virginia E

    2016-01-01

    Prader-Willi syndrome (PWS) is a complex, multisystem genetic disorder characterized by endocrine, neurologic, and behavioral abnormalities. We report the first case of an unbalanced de novo reciprocal translocation of chromosomes 15 and 19, 45,XY,-15,der(19)t(15;19)(q12;p13.3), resulting in monosomy for the PWS critical chromosome region. Our patient had several typical features of PWS including infantile hypotonia, a poor suck and feeding difficulties, tantrums, skin picking, compulsions, small hands and feet, and food seeking, but not hypopigmentation, a micropenis, cryptorchidism or obesity as common findings seen in PWS at the time of examination at 6 years of age. He had seizures noted from 1 to 3 years of age and marked cognitive delay. High-resolution SNP microarray analysis identified an atypical PWS type I deletion in chromosome 15 involving the proximal breakpoint BP1. The deletion extended beyond the GABRB3 gene but was proximal to the usual distal breakpoint (BP3) within the 15q11q13 region, and GABRA5, GABRG3, and OCA2 genes were intact. No deletion of band 19p13.3 was detected; therefore, the patient was not at an increased risk of tumors from the Peutz-Jeghers syndrome associated with a deletion of the STK11 gene. © 2016 S. Karger AG, Basel.

  5. 40 CFR 112.13-112.15 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... POLLUTION PREVENTION Requirements for Animal Fats and Oils and Greases, and Fish and Marine Mammal Oils; and for Vegetable Oils, including Oils from Seeds, Nuts, Fruits, and Kernels. §§ 112.13-112.15 [Reserved] ...

  6. Parent-Reported Bullying and Child Weight Gain between Ages 6 and 15.

    Science.gov (United States)

    Sutin, Angelina R; Robinson, Eric; Daly, Michael; Terracciano, Antonio

    2016-12-01

    Childhood bullying has long-term negative mental and physical health correlates, including weight gain and symptoms of depression. The purpose of this research is to examine whether bullying in the first year of school is associated with greater weight gain by early adolescence and whether adolescent depressive symptoms mediate this association. Data were drawn from the Longitudinal Study of Australian Children. Children (N = 3929) were measured every 2 years; BMI and waist circumference were available from ages 4 to 15. Parents reported on bullying at age 6. Children reported on their depressive symptoms at ages 12-13. Participants who weighed in the obese category at age 4 had an over 50% increased risk of being bullied in school at age 6. Being bullied at age 6 was associated with excess weight gain between ages 6 and 15, defined as either BMI or waist circumference. Depressive symptoms at age 12 partially explained the association between bullying and increases in adiposity. None of the associations varied by gender. Similar to other forms of peer victimization, bullying early in school is associated with greater weight gain through early adolescence; depressive symptom is one mechanism that contributes to this association.

  7. Synthesis of (+-)-[1,1'-15N2, 2'-13C]-trans-3'-methylnicotine

    International Nuclear Information System (INIS)

    Sirimanne, S.R.; Maggio, V.L.; Patterson, D.G. Jr.

    1992-01-01

    The synthesis of (±)- [1,1'- 15 N 2 , 2'- 13 C]-trans-3'-methylnicotine is reported. 15 N-3-Bromopyridine obtained from bromination of pyridine was formylated with nBuLi/[carbonyl- 13 C]-methyl formate. The resulting 15 n-Pyridine-3-[ 13 C-carbonyl]-carboxaldehyde was reacted with 15 N-methylamine and then the resulting Schiff's base was condensed with succinic anhydride to give (±)- [1,1'- 15 N 2 , 5'- 13 C]-trans-4'-carboxycotinine. Reduction with lithium aluminum hydride and mesylation followed by reduction with Zn/NaI gave (±)-[1,1'- 15 N 2 , 2'- 13 C]-trans-3'-methylnicotine. (Author)

  8. The Relationship between Bible Reading and Attitude toward Substance Use among 13-15 Year Olds

    Science.gov (United States)

    Francis, Leslie J.

    2002-01-01

    The relationship between Bible reading and attitude toward drug use is examined among a sample of 25,888 teenagers, 13-15 year olds, throughout England and Wales. Information about sex, age, personality, belief in God, and church attendance was also considered. The conclusion is that Bible reading makes a small but significant contribution to…

  9. 40 CFR 721.6505 - Polymers of C13C15 oxoalcohol ethoxolates.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Polymers of C13C15 oxoalcohol... Specific Chemical Substances § 721.6505 Polymers of C13C15 oxoalcohol ethoxolates. (a) Chemical substance... polymers of C13C15 oxoalcohol ethoxolates (PMNs P-96-950/951) are subject to reporting under this section...

  10. Going for (Nano)Gold: A University Open Day Experiment for Year 13 Students

    Science.gov (United States)

    Baker, Christopher; Patel, Bhavik Ani; Cragg, Alexander S.; Cragg, Peter J.

    2013-01-01

    Open day activities rarely give applicants a real sense of the practical and intellectual work that goes on in university chemistry departments. We devised an experiment for year 13 (age 17-18) students based on the size-dependent colours of gold nanoparticles and linked this to current research in diagnostic medicine. The experience was designed…

  11. 15q13.3 microdeletions increase risk of idiopathic generalized epilepsy

    DEFF Research Database (Denmark)

    Helbig, Ingo; Mefford, Heather C; Sharp, Andrew J

    2009-01-01

    We identified 15q13.3 microdeletions encompassing the CHRNA7 gene in 12 of 1,223 individuals with idiopathic generalized epilepsy (IGE), which were not detected in 3,699 controls (joint P = 5.32 x 10(-8)). Most deletion carriers showed common IGE syndromes without other features previously...... associated with 15q13.3 microdeletions, such as intellectual disability, autism or schizophrenia. Our results indicate that 15q13.3 microdeletions constitute the most prevalent risk factor for common epilepsies identified to date....

  12. Synthesis of [1,3 - 15 N2] uracil

    International Nuclear Information System (INIS)

    Chiriac, M.; Axente, D.

    2001-01-01

    The synthesis of 15 N labelled uracil, using CO( 15 NH 2 ) 2 as starting material, is presented. The experimental procedure is an adaptation of the synthesis methods for the corresponding unlabelled compounds. Urea- 15 N 2 used as starting material was obtained from H 15 NO 3 (99 at.% 15 N) produced at National Institute for Research and Development of Isotopic and Molecular Technologies, Cluj-Napoca.The uracil structure was determined using the mass spectrometry method and the isotopic labelling was determined by the same method on the molecular compound. The synthesis scheme of (1,3- 15 N 2 ) uracil is presented. (authors)

  13. Fe-15Ni-13Cr austenitic stainless steels for fission and fusion reactor applications. II. Effects of minor elements on precipitate phase stability during thermal aging

    International Nuclear Information System (INIS)

    Lee, E.H.; Mansur, L.K.

    2000-01-01

    The precipitate phase stability in Fe-15Ni-13Cr base austenitic alloys was investigated as a function of minor alloying additions after thermally aging at 600 deg. C and 675 deg. C for times ranging from 24 h to one year. Seven major precipitate phases were found in aged specimens, including M 23 C 6 , Laves, Eta (η), TiO, NbC, MC, and M 2 P. The types and amounts of precipitate phases varied with alloying element additions, aging temperature, and aging time. By analyzing the composition of each individual particle, it was possible to determine the essential constituent elements for each phase. From this information, a strategy to promote or suppress certain precipitate phases was developed. Among the seven phases, the most desirable precipitate phases were considered to be MC and M 2 P, because these particles form on a fine scale with a high number density and, therefore, can serve as effective gas atom trap sites under irradiation

  14. Anthropometric characteristics and motor abilities in 13-15 year old female volleyball players

    OpenAIRE

    Nešić, Goran; Majstorović, Nikola; Sikimić, Milan; Marković, Srđan; Ilić, Dejan; Grbić, Vladimir; Osmankač, Nedžad; Savić, Zoran

    2014-01-01

    The goal of this research was to determine whether there is a difference in the manifestation of measured anthropometric characteristics and tested motor abilities of female volleyball players that are 13-15 years old. The sample of participants consists of 62 female volleyball players divided into three groups according to their age. The sample of variables has two sub-samples: 18 variables belonging to anthropometric space and 14 variables belonging to the space of motor skills. A variance ...

  15. Adult anthropometric measures and socio-demographic factors influencing age at menarche of university students in malaysia.

    Science.gov (United States)

    Hossain, Md Golam; Wee, Ai-Sze; Ashaie, Maeirah; Kamarul, T

    2013-09-01

    Early onset of menarche has been shown to be associated with breast cancer and ischaemic heart disease. Studies on age at menarche of the Malaysian population are poorly documented. This study aimed to determine the influence of anthropometric and socio-demographic factors on the age at menarche of university students in Malaysia. Data were obtained in 2010-11 from 961 students between the ages of 18 and 25 years from the University of Malaya using stratified sampling, and multiple regression analysis was applied. Sixty-three per cent of students reached menarche at the age of 12 or 13 years, with the mean and median of age at menarche being 12.45 ± 1.17 and 12.01 years, respectively. Menarcheal age was positively associated with height (pObese and overweight students reached menarche earlier than students who were underweight or of normal weight (p<0.01). The variations in age at menarche among the Malaysian ethnic groups were statistically insignificant. The results suggest that heavier and first-born students from small families are more likely to attain menarche earlier than their counterparts.

  16. Liaison amid problem behavior and traumatic dental injury among children aged 12-15 years in Bhopal

    Directory of Open Access Journals (Sweden)

    Naveen S Yadav

    2015-01-01

    Full Text Available Introduction: Liaison amid problem behavior and traumatic dental injury among children aged 13-15 years are consequential due to multifactorial dental, orofacial skeletal, psycosocial behavior pattern. The probable etiology is been equated overjet; inadequate lip coverage is the major etiological factors accountable for traumatic dental injuries. Aims: The aim was to assess the relationship of problem behavior, type of lip coverage, and the size of overjet with the traumatic dental injury among children aged 12-15 years. Materials and Methods: A cross-sectional study was conducted among 200 children aged 12-15 years in Bhopal, India. Data were collected through clinical examinations in children and interviews with parents. Traumatic injuries were recorded according to Garcia-Goday′s classification. The informant - rated version of the strengths and difficulties questionnaire was used to identify problems behavior. Results: About 16.4% subjects had more than 5 mm overjet, and 20.4% subjects had inadequate lip coverage. The largest number of injuries were presented by 15-year-old children (43.90% followed by 14 and 13 years old children. The traumatic dental injury showed 6.8% association with problem behavior, age, sex, type of lip coverage, and the size of overjet. Conclusion: Problem behavior along with the type of lip coverage and the size of overjet plays a role in the occurrence of traumatic dental injury.

  17. Prader-Willi syndrome due to an unbalanced de novo translocation [t(15;19)(q12;p13.3)

    Science.gov (United States)

    Dang, Vy; Surampalli, Abhilasha; Manzardo, Ann M; Youn, Stephanie; Butler, Merlin G; Gold, June-Anne; Kimonis, Virginia

    2018-01-01

    Background and Aims Prader-Willi syndrome (PWS) is a complex, multisystem genetic disorder characterized by endocrine, neurologic and behavioral abnormalities. We report the first case of an unbalanced de-novo reciprocal translocation of chromosome 15 and 19: 45,XY,-15, der (19)t(15;19)(q12;p13.3) resulting in monosomy for the PWS chromosome critical region. We performed high resolution SNP microarray to characterize the breakpoints. Case report Our patient had several typical features for PWS including infantile hypotonia, a poor suck and feeding difficulties, tantrums, skin picking, compulsions, small hands and feet and food seeking but not hypopigmentation, a micropenis, cryptorchidism or obesity as common findings seen in PWS at the time of examination at 6 years of age. He had seizures noted from 1 to 3 years of age and marked cognitive delay. Results High resolution SNP microarray analysis identified an atypical PWS Type I deletion of chromosome 15 involving proximal breakpoint BP1. The deletion extended beyond the GABRB3 gene but was proximal to the usual distal breakpoint (BP3) within the 15q11-q13 region and GABRA5, GABRG3 and OCA2 genes were intact. Conclusion We report a case with atypical features for PWS associated with an unbalanced de-novo reciprocal translocation resulting in monosomy for the 15q11.1–15q12 with intact GABRA5, GABRG3 and OCA2 genes. No deletion of 19p13.3 band was detected therefore the patient was not at an increased risk of tumors from Peutz-Jeghers syndrome associated with a deletion of the STK11 gene. PMID:27894106

  18. A cross-country comparison of the prevalence of exposure to tobacco advertisements among adolescents aged 13-15 years in 20 low and middle income countries.

    Science.gov (United States)

    Agaku, Israel T; Adisa, Akinyele O; Akinyamoju, Akindayo O; Agboola, Samuel O

    2013-01-01

    This study assessed the prevalence and influence of exposure to pro-tobacco advertisements among adolescents in 20 low and middle income countries (LMICs). The 2007-2008 Global Youth Tobacco Survey was analyzed for students aged 13-15 years in 20 LMICs. Overall and sex-specific prevalence of exposure to tobacco advertisements in several media, as well as the prevalence of smoking susceptibility (i.e., the lack of a firm commitment among never smokers not to smoke in the future or if offered a cigarette by a friend) were assessed. The variability of the point estimates was assessed using 95% confidence intervals (CI). Logistic regression was used to assess the effect of exposure to multiple (i.e., ≥2) pro-tobacco advertisements on current smoking, adjusting for age and sex (P advertisement sources ranged as follows: movies/videos (78.4% in Lesotho to 97.8% in Belize); television programs (48.7% in Togo to 91.7% in the Philippines); newspapers/magazines (29.5% in Togo to 89.7% in the Philippines); and outdoor community events (30.6% in Rwanda to 79.4% in the Philippines). The overall proportion of never smokers who were susceptible to cigarette smoking ranged from 3.7% in Sri Lanka to 70.1% in Kyrgyzstan. Exposure to ≥2 sources of pro-tobacco advertisements was associated with significantly increased odds of cigarette smoking among adolescents in several countries including South Africa (adjusted odds ratio, aOR = 4.11; 95% CI:2.26-7.47), Togo (aOR = 3.77; 95% CI:1.27-11.21), the Former Yugoslav Republic of Macedonia (aOR = 1.42; 95% CI:1.01-1.99), Republic of Moldova (aOR = 1.53; 95% CI:1.11-2.12), Belize (aOR = 13.95; 95% CI:1.91-102.02), Panama (aOR = 5.14; 95% CI: 2.37-11.14) and Mongolia (aOR = 1.52; 95% CI:1.19-1.94). Prevalence of exposure to various pro-tobacco advertisements was high among adolescents in the LMICs surveyed. Enhanced and sustained national efforts are needed to reduce exposure to all forms of tobacco advertising and promotional activities.

  19. Breast Feeding, Sex and Body Composition as Correlates of Stunting Among Kenyan Children at 6 and 15 Months of Age

    International Nuclear Information System (INIS)

    Konyole, Silvenus; Omollo, Selina; Skau, Jutta; Michaelsen, Kim; Roos, Nanna; Friis, Henrik; Kinyuru, John; Owuor, Bethuel; Estambale, Benson; Owino, Victor

    2014-01-01

    Full text: Introduction and objective: Stunting is prevalent in young children in low-income countries, and has detrimental effects on psychomotor development and later working capacity. The objective of this study was to assess the association of body composition (fat-free mass and fat mass), breastfeeding and sex with stunting in Kenyan children aged 6 and 15 months Subjects and Method: As part of a nutrition trial conducted in Western Kenya, 449 six months old infants were recruited if MUAC≥11.5 cm. At six and 15 months of age, weight, recumbent length, skinfolds and mid-upper arm circumference (MUAC) were measured. Deuterium oxide dilution method was used to determine body fat and fat-free-mass. A predose saliva sample was taken prior to a dose to the infant of 0.5 g deuterium oxide per kg of body weight. Postdose saliva samples were taken after 2 and 3 hours, respectively. Deuterium enrichment was measured using Fourier Transformed Infrared Spectrophotometer. Linear regression was used to assess the association of sex, breastfeeding, fat-free mass index (FFMI), fat mass index (FMI) and body mass index (BMI) as correlates of stunting Results: At 6 months, males had FMI being 14.03 kg/m2 (95% CI 13.80; 14.26) compared to females at 13.67(95% CI 13.40; 13.94). At 15 months males had an FMI of 14.74(95% CI 14.48; 14.99) while females had 14.41(95% CI 14.18; 14.64). At age 6 and 15 months, females had a lower -0.45 (95% CI -2.37; 1.46) kg/m2 and -0.36 (95% CI -0.59;-0.13) kg/m2 FFMI compared to girls, respectively. Stunting was not associated with body composition at neither 6 nor 15 months. Those who stopped breastfeeding before 15 months (11.1%) had a 0.01(95% CI 0.002; 0.02) kg/m2 lower FFMI when they reached 15 months. Conclusion: Longer duration of breastfeeding was associated with higher FFMI in early infancy in resource poor settings .Stunting was associated with lower FMI at the age of 6 months but not at 15 months. Wasting was associated with a deficit

  20. Interleukin-13 and age-related macular degeneration

    Directory of Open Access Journals (Sweden)

    Bo Fu

    2017-04-01

    Full Text Available AIM: To identify the effects of interleukin (IL-13 on retinal pigment epithelial (RPE cells and the IL-13 level in aqueous humor of age-related macular degeneration (AMD patients. METHODS: IL-13 levels in aqueous humor specimens from AMD patients were detected with enzyme-linked immunosorbent assay (ELISA. ARPE-19 cells were treated with 10 ng/mL IL-13 for 12, 24, and 48h. The cell proliferaton was evaluated by the MTS method. The mRNA and protein levels of α-SMA and ZO-1 were evaluated with quantitative real-time polymerase chain reaction (qRT-PCR and Western blot respectively. The expression of tumor necrosis factor-α (TNF-α, transforming growth factor-β (TGF-β and vascular endothelial growth factor (VEGF were assessed by ELISA. RESULTS: IL-13 levels in the aqueous humor of patients with AMD were significantly higher than those in the control (167.33±17.64 vs 27.12±5.65 pg/mL; P<0.01. In vitro, IL-13 of high concentrations (10, 15, and 20 ng/mL inhibited ARPE-19 cell proliferation. α-SMA mRNA in ARPE-19 cell were increased (1.017±0.112 vs 1.476±0.168; P<0.001 and ZO-1 decreased (1.051±0.136 vs 0.702±0.069; P<0.001 after treated with 10 ng/mL IL-13 for 48h. The protein expression of α-SMA and ZO-1 also showed the same tendency (α-SMA: P=0.038; ZO-1: P=0.008. IL-13 significantly reduced the level of TNF-α (44.70±1.67 vs 31.79±3.53 pg/mL; P=0.005 at 48h, but the level of TGF-β2 was significantly increased from 34.44±2.92 to 57.61±6.31 pg/mL at 24h (P=0.004 and from 61.26±1.11 to 86.91±3.59 pg/mL at 48h (P<0.001. While expressions of VEGF didn’t change after IL-13 treatment. CONCLUSION: IL-13 in vitro inhibit ARPE-19 cell proliferation and expression in the aqueous may be associated with AMD.

  1. 15 CFR 740.13 - Technology and software-unrestricted (TSU).

    Science.gov (United States)

    2010-01-01

    ... time the Internet location is changed, but you are not required to notify them of updates or... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Technology and software-unrestricted (TSU). 740.13 Section 740.13 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign...

  2. Prevalence of Unique Pediatric Pathologies Encountered by Paramedic Students Across Age Groups.

    Science.gov (United States)

    Ernest, Eric V; Brazelton, Tom B; Carhart, Elliot D; Studnek, Jonathan R; Tritt, Patricia L; Philip, Genghis A; Burnett, Aaron M

    2016-08-01

    Introduction Traditionally, Emergency Medical Services (EMS) educators have divided the pediatric population into age groups to assist in targeting their clinical and didactic curriculum. Currently, the accrediting body for paramedic training programs requires student exposure to pediatric patients based entirely on age without specifying exposure to specific pathologies within each age stratification. Identifying which pathologies are most common within the different pediatric age groups would allow educators to design curriculum targeting the most prevalent pathologies in each age group and incorporating the physiologic and psychological developmental milestones commonly seen at that age. Hypothesis It was hypothesized that there are unique clusterings of pathologies, represented by paramedic student primary impressions, that are found in different age groups which can be used to target provider education. This is a retrospective review of prospectively collected data documented by paramedic students in the Fisdap (Field Internship Student Data Acquisition Project; Saint Paul, Minnesota USA) database over a one-year period. For the purposes of this study, pediatric patients were defined arbitrarily as those between the ages of 0-16 years. All paramedic student primary impressions recorded in Fisdap for patients aged 0-16 years were abstracted. Primary impression by age was calculated and graphed. The frequency of primary impression was then assessed for significance of trend by age with an alpha ≤.05 considered significant. The following primary impressions showed clinically and statistically significant variability in prevalence among different pediatric age groups: respiratory distress, medical-other, abdominal pain, seizure, overdose/poisoning, behavioral, and cardiac. In patients less than 13 years old, respiratory and other-medical were the most common two primary impressions and both decreased with age. In patients 5-16 years old, the prevalence of

  3. Neutronic evaluation of annular fuel rods to assemblies 13 x 13, 14 x 14 and 15 x 15

    International Nuclear Information System (INIS)

    Silva, Raphael H.M.; Ramos, Mario C.; Velasquez, Carlos E.; Silva, Clarysson A.M. da; Pereira, Cláubia; Costa, Antonella L.

    2017-01-01

    Research and development in nuclear reactor field has been proposed a new concept of fuel rod such as annular shape. The design of the annular fuel rods allows the coolant flow through the inner and outer side of it. Such project was proposed as an alternative to the traditional fuel rods used in LWR reactors. This new geometry allows an increase in power density in the reactor core with greater heat transfer from the fuel to the coolant which reduces the temperature in central region of the rod, in which a better configuration and dimension of fuel elements are aimed due to improvement of cooling in possible replacement of PWR traditional rods for annular rods. The aim of this work is to evaluate the neutronic parameters of fuel element with annular fuel rods where three configurations were studied: 13 x 13, 14 x 14 and 15 x 15. The goal is compare the neutronic between the advanced and the standard fuel assembly 16 x 16. In these studies, the external dimension and the moderator to fuel volume ratio (V M /V F ) of standard 16 x 16 is the same in all annular fuels assemblies. The MCNPX 2.6.0 (Monte Carlo N-Particle eXtended – version 2.6.0) code was used in all simulations. After all procedures, the annular fuel assemblies 13 have obtained greater neutronics parameters and were selected to more neutronics simulations. (author)

  4. Neutronic evaluation of annular fuel rods to assemblies 13 x 13, 14 x 14 and 15 x 15

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Raphael H.M.; Ramos, Mario C.; Velasquez, Carlos E.; Silva, Clarysson A.M. da; Pereira, Cláubia; Costa, Antonella L., E-mail: rapha.galo@hotmail.com, E-mail: marc5663@gmail.com, E-mail: carlosvelcab@hotmail.com, E-mail: clarysson@nuclear.ufmg.br, E-mail: claubia@nuclear.ufmg.br, E-mail: antonella@nuclear.ufmg.br [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Departamento de Engenharia Nuclear

    2017-07-01

    Research and development in nuclear reactor field has been proposed a new concept of fuel rod such as annular shape. The design of the annular fuel rods allows the coolant flow through the inner and outer side of it. Such project was proposed as an alternative to the traditional fuel rods used in LWR reactors. This new geometry allows an increase in power density in the reactor core with greater heat transfer from the fuel to the coolant which reduces the temperature in central region of the rod, in which a better configuration and dimension of fuel elements are aimed due to improvement of cooling in possible replacement of PWR traditional rods for annular rods. The aim of this work is to evaluate the neutronic parameters of fuel element with annular fuel rods where three configurations were studied: 13 x 13, 14 x 14 and 15 x 15. The goal is compare the neutronic between the advanced and the standard fuel assembly 16 x 16. In these studies, the external dimension and the moderator to fuel volume ratio (V{sub M}/V{sub F}) of standard 16 x 16 is the same in all annular fuels assemblies. The MCNPX 2.6.0 (Monte Carlo N-Particle eXtended – version 2.6.0) code was used in all simulations. After all procedures, the annular fuel assemblies 13 have obtained greater neutronics parameters and were selected to more neutronics simulations. (author)

  5. Cytomegalovirus Infection Triggers the Secretion of the PPARγ Agonists 15-Hydroxyeicosatetraenoic Acid (15-HETE and 13-Hydroxyoctadecadienoic Acid (13-HODE in Human Cytotrophoblasts and Placental Cultures.

    Directory of Open Access Journals (Sweden)

    Kaoutar Leghmar

    Full Text Available Congenital infection by human cytomegalovirus (HCMV is a leading cause of congenital abnormalities of the central nervous system. Placenta infection by HCMV allows for viral spread to fetus and may result in intrauterine growth restriction, preeclampsia-like symptoms, or miscarriages. We previously reported that HCMV activates peroxisome proliferator-activated receptor gamma (PPARγ for its own replication in cytotrophoblasts. Here, we investigated the molecular bases of PPARγ activation in infected cytotrophoblasts.We show that onboarded cPLA2 carried by HCMV particles is required for effective PPARγ activation in infected HIPEC cytotrophoblasts, and for the resulting inhibition of cell migration. Natural PPARγ agonists are generated by PLA2 driven oxidization of linoleic and arachidonic acids. Therefore, using HPLC coupled with mass spectrometry, we disclosed that cellular and secreted levels of 13-hydroxyoctadecadienoic acid (13-HODE and 15-hydroxyeicosatetraenoic acid (15-HETE were significantly increased in and from HIPEC cytotrophoblasts at soon as 6 hours post infection. 13-HODE treatment of uninfected HIPEC recapitulated the effect of infection (PPARγ activation, migration impairment. We found that infection of histocultures of normal, first-term, human placental explants resulted in significantly increased levels of secreted 15-HETE and 13-HODE.Our findings reveal that 15-HETE and 13-HODE could be new pathogenic effectors of HCMV congenital infection They provide a new insight about the pathogenesis of congenital infection by HCMV.

  6. A Quantitative Electrophysiological Biomarker of Duplication 15q11.2-q13.1 Syndrome.

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    Joel Frohlich

    Full Text Available Duplications of 15q11.2-q13.1 (Dup15q syndrome are highly penetrant for autism spectrum disorder (ASD. A distinct electrophysiological (EEG pattern characterized by excessive activity in the beta band has been noted in clinical reports. We asked whether EEG power in the beta band, as well as in other frequency bands, distinguished children with Dup15q syndrome from those with non-syndromic ASD and then examined the clinical correlates of this electrophysiological biomarker in Dup15q syndrome.In the first study, we recorded spontaneous EEG from children with Dup15q syndrome (n = 11, age-and-IQ-matched children with ASD (n = 10 and age-matched typically developing (TD children (n = 9 and computed relative power in 6 frequency bands for 9 regions of interest (ROIs. Group comparisons were made using a repeated measures analysis of variance. In the second study, we recorded spontaneous EEG from a larger cohort of individuals with Dup15q syndrome (n = 27 across two sites and examined age, epilepsy, and duplication type as predictors of beta power using simple linear regressions.In the first study, spontaneous beta1 (12-20 Hz and beta2 (20-30 Hz power were significantly higher in Dup15q syndrome compared with both comparison groups, while delta (1-4 Hz was significantly lower than both comparison groups. Effect sizes in all three frequency bands were large (|d| > 1. In the second study, we found that beta2 power was significantly related to epilepsy diagnosis in Dup15q syndrome.Here, we have identified an electrophysiological biomarker of Dup15q syndrome that may facilitate clinical stratification, treatment monitoring, and measurement of target engagement for future clinical trials. Future work will investigate the genetic and neural underpinnings of this electrophysiological signature as well as the functional consequences of excessive beta oscillations in Dup15q syndrome.

  7. Bullying victimization among 13 to 15-year-old school children: results from two comparative studies in 66 countries and regions

    DEFF Research Database (Denmark)

    Due, Pernille; Holstein, Bjørn Evald

    2008-01-01

    AIM: to examine the prevalence of bullying victimization in 66 countries and territories from five continents based on data from two large international surveys: the 2001/2 Health Behavior in School-aged Children survey (HBSC) and the Global School-based Students Health Survey (GSHS). The surveys...... provide nationally representative, cross-sectional information on 13-15-year-old school children (N = 218,104). OUTCOME MEASURES: Bullying victimization, once or more within the past 2 months (HBSC)/30 days (GSHS). RESULTS: On average, 32.1% of the children were bullied at school at least once within...... the past 2 months in countries involved in the HBSC study and 37.4% of children were bullied at least one day within the past 30 days in countries involved in the GSHS study. In both surveys, a large variation in prevalence was found across countries. The lowest prevalence in the GSHS survey was observed...

  8. Synthesis and E.I.M.S. fragmentation analysis of [1,3-{sup 15} N{sub 2}] xanthine and [1,3-{sup 15} N{sub 2}] caffeine

    Energy Technology Data Exchange (ETDEWEB)

    Kenani, A. [Tunis Univ. (Tunisia). Faculte de Medecine; Bernier, J.-L. [Laboratoire de Chimie Organique Physique (France); Henichart, J.-P. [UCB-Pharma (Belgium)

    1995-02-01

    HPLC and mass spectrometry can be used to isolate and identify all metabolites of caffeine in plasma of patients. The synthesis of [1,3-{sup 15}N{sub 2}] xanthine and [1,3-{sup 15}N{sub 2}] caffeine are of interest in the elucidation of mass spectrometry fragmentation pathways and unambiguous determination of metabolites, especially uric acid which exists as a natural constituent of human plasma. (Author).

  9. DEVELOPMENT VARIABILITY OF LONGITUDINAL SPINE FEATURES IN CHILDREN AGING 7-15 YEARS OLD

    Directory of Open Access Journals (Sweden)

    Katarzyna Kochan

    2010-06-01

    Full Text Available Introduction. Increased body growth is connected with higher sensitivity to environmental influence and may be a cause of instability of body posture. This happens when trunk and lower limbs growth is more intense. Because body posture disorders are most often diagnosed in children and school adolescents, the sample chosen were subjects between 7 and 15 years old. Material and methods. The data was gathered in 2002 in the town of Polkowice. Examination concerned 2706 boys and girls aged 7 to 15 years old. The measurement included basic somatic features and for the body posture photogrammetric method was used. Results. It was indicated that the relative trunk length in both sexes was decreasing in early school period but in the three oldest groups of age there was a significant increase. The height of kyphosis was increasing significantly in both sexes with age. Most intensive growth of this parameter was observed between 12 and 13 years old subjects. In both sexes there could be seen significant increase of kyphosis depth between 12 and 14 years old and also the decrease of lumbar lordosis between 12 and 13 years old subjects. Conclusion. Significant increase of thoracical spine relative height and lumbar lordosis depth in adolescents in both sexes can be one of the causes of weakening spine stability and affect correct body posture development.

  10. A cross-country comparison of the prevalence of exposure to tobacco advertisements among adolescents aged 1315 years in 20 low and middle income countries

    Science.gov (United States)

    2013-01-01

    Background This study assessed the prevalence and influence of exposure to pro-tobacco advertisements among adolescents in 20 low and middle income countries (LMICs). Methods The 2007–2008 Global Youth Tobacco Survey was analyzed for students aged 1315 years in 20 LMICs. Overall and sex-specific prevalence of exposure to tobacco advertisements in several media, as well as the prevalence of smoking susceptibility (i.e., the lack of a firm commitment among never smokers not to smoke in the future or if offered a cigarette by a friend) were assessed. The variability of the point estimates was assessed using 95% confidence intervals (CI). Logistic regression was used to assess the effect of exposure to multiple (i.e., ≥2) pro-tobacco advertisements on current smoking, adjusting for age and sex (P advertisement sources ranged as follows: movies/videos (78.4% in Lesotho to 97.8% in Belize); television programs (48.7% in Togo to 91.7% in the Philippines); newspapers/magazines (29.5% in Togo to 89.7% in the Philippines); and outdoor community events (30.6% in Rwanda to 79.4% in the Philippines). The overall proportion of never smokers who were susceptible to cigarette smoking ranged from 3.7% in Sri Lanka to 70.1% in Kyrgyzstan. Exposure to ≥2 sources of pro-tobacco advertisements was associated with significantly increased odds of cigarette smoking among adolescents in several countries including South Africa (adjusted odds ratio, aOR = 4.11; 95% CI:2.26-7.47), Togo (aOR = 3.77; 95% CI:1.27-11.21), the Former Yugoslav Republic of Macedonia (aOR = 1.42; 95% CI:1.01-1.99), Republic of Moldova (aOR = 1.53; 95% CI:1.11-2.12), Belize (aOR = 13.95; 95% CI:1.91-102.02), Panama (aOR = 5.14; 95% CI: 2.37-11.14) and Mongolia (aOR = 1.52; 95% CI:1.19-1.94). Conclusion Prevalence of exposure to various pro-tobacco advertisements was high among adolescents in the LMICs surveyed. Enhanced and sustained national efforts are needed to reduce exposure to all forms of tobacco

  11. 15q13.3 homozygous knockout mouse model display epilepsy-, autism- and schizophrenia-related phenotypes

    DEFF Research Database (Denmark)

    Forsingdal, A; Fejgin, Kim; Nielsen, Viggo

    2016-01-01

    The 15q13.3 microdeletion syndrome is caused by a 1.5-MB hemizygous microdeletion located on 15q13.3 affecting seven genes: FAN1; MTMR10; TRPM1; miR-211; KLF13; OTUD7A; and CHRNA7. The 15q13.3 microdeletion increases the risk of intellectual disability, epilepsy, autism spectrum disorder...

  12. Generation 1.5--a different kind of millennial student.

    Science.gov (United States)

    Davidson, Emily J

    2011-01-01

    Much attention has been paid to so-called "millennial students" in recent years, particularly regarding their relationship to technology, learning, and communication. Less notice has been taken of another kind of millennial student increasingly represented in our classrooms --those who were born in another country, but received a significant amount of their schooling here. Often referred to as Generation 1.5 because they have language characteristics in common with first- and second-generation immigrants, these bilingual students are a valuable resource for the physician assistant (PA) profession. However, just as teaching native-born millennial students may require some adjustment of instructional methods, Generation 1.5 students will require PA educators to pay closer attention to some aspects of teaching and learning. This article will discuss some of the particular challenges that Generation 1.5 students face and will argue that these challenges can be met in ways that are likely to help other nontraditional students as well.

  13. Prevalence of obesity among students aged 6 to 12 in China: a meta-analysis

    Directory of Open Access Journals (Sweden)

    Yue Tian

    2015-12-01

    Full Text Available Background: In recent years, obesity has become a major public health problem worldwide. It has been estimated that 8% of children are obese. This study evaluates the overall prevalence of obesity in primary students in recent years. Methods: Publications from 2011 and 2015 on the obesity prevalence among primary school students aged 6 to 12 in China were retrieved from the databases PubMed and Wanfang Data. Obesity was defined using the International Obesity Task Force standard body mass index cutoff points established for children. MetaAnalyst 3.13 software was used to calculate the total prevalence of obesity among primary school students in recent years. Results: After evaluation of the quality of the articles, 14 papers were finally included in our study. The pooled prevalence of obesity in students aged 6 to 12 is 10.2% (95% CI: 7.1–14.6%. Conclusion: Our results indicate that obesity is prevalent in students aged 6 to 12 in China. We believe that appropriate measures should be taken to control this situation.

  14. Health-related physical fitness and weight status in 13- to 15-year-old Latino adolescents. A pooled analysis.

    Science.gov (United States)

    García-Hermoso, Antonio; Correa-Bautista, Jorge E; Olloquequi, Jordi; Ramírez-Vélez, Robinson

    2018-05-05

    The aim of this study was to investigate the relation between health-related physical fitness and weight status in 13- to 15-year-old Latino adolescents. The final sample consisted of 73,561 adolescents aged 13-15 years (35,175 girls) from Chile (n=48,771) and Colombia (n=24,790). Cardiorespiratory and musculoskeletal fitness were measured using 20-m shuttle run (relative peak oxygen uptake - VO 2peak ) and standing broad jump test (lower body explosive strength), respectively. The International Obesity Task Force definition was used to define weight status (i.e., underweight, normal weight, overweight, and obese). The present study found an inverted J-shape relationship between body mass index, cardiorespiratory fitness, and musculoskeletal fitness in both genders and all age groups (pfitness (based on new international criterion-referenced standards) profile when compared with their normal weight peers, except in girls aged 14 (p=0.268) and 15 years (p=0.280). The present results indicate low cardiorespiratory fitness and musculoskeletal fitness levels in underweight, overweight, and obese adolescents when compared with their normal weight peers. The findings appear to suggest that exercise programs should to decrease fat mass in overweight/obese adolescents and increase muscle mass in underweight adolescents. Copyright © 2018 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

  15. Tracking drinking behaviour from age 15-19 years

    DEFF Research Database (Denmark)

    Andersen, Anette; Due, Pernille; Holstein, Bjørn E

    2003-01-01

    beverages at age 15 increased the risk of drinking alcohol weekly at the age of 19 [odds ratio (OR)-values from 1.11 to 3.53]. Drunkenness among the 15-year-old boys and the use of spirits of the 15-year-old girls showed the strongest predictive relationship with excessive consumption at age 19 [OR = 2...... phenomenon. It was a behaviour that tracked into young adulthood, leaving the adolescents at increased risk of being long-term, large-scale consumers....

  16. [Morphometrical analyze of the middle cerebral artery system at the 13-15 weeks fetuses].

    Science.gov (United States)

    Macovei, Georgeta Nataşa; Varlam, H; St Antohe, D

    2002-01-01

    Tele-encephalization process is accompanied by the appearance and progressive complication of the middle cerebral artery system. The aim of our study is to analyze the morphometrical parameters of the middle cerebral artery branches in the beginning of the edification of its system. We used 162 cerebral hemispheres from 88 fetuses aged of 13-15 weeks. Middle cerebral artery system was injected with a gelatin-China ink mixture and images recorded by means of a Zeiss surgical microscope. Parameters evaluation (length, proximal and distal diameters, external surface, volume, angles of bifurcation) was realized with KS-300 program. At this early age middle cerebral artery system has only 4-5 generations of branches usually resulting from acute angle bifurcations.

  17. Ageing processes and soil microbial community effects on the biodegradation of soil 13C-2,4-D nonextractable residues

    International Nuclear Information System (INIS)

    Lerch, T.Z.; Dignac, M.-F.; Nunan, N.; Barriuso, E.; Mariotti, A.

    2009-01-01

    The biodegradation of nonextractable residues (NER) of pesticides in soil is still poorly understood. The aim of this study was to evaluate the influence of NER ageing and fresh soil addition on the microbial communities responsible for their mineralisation. Soil containing either 15 or 90-day-old NER of 13 C-2,4-D (NER15 and NER90, respectively) was incubated for 90 days with or without fresh soil. The addition of fresh soil had no effect on the mineralisation of NER90 or of SOM, but increased the extent and rate of NER15 mineralisation. The analyses of 13 C-enriched FAME (fatty acids methyl esters) profiles showed that the fresh soil amendment only influenced the amount and structure of microbial populations responsible for the biodegradation of NER15. By coupling biological and chemical analyses, we gained some insight into the nature and the biodegradability of pesticide NER. - Ageing processes influence the NER mineralisation rate and the microbial population involved.

  18. Negative ageing stereotypes in students and faculty members from three health science schools.

    Science.gov (United States)

    León, Soraya; Correa-Beltrán, Gloria; Giacaman, Rodrigo A

    2015-06-01

    To explore the ageing stereotypes held by health students and faculty members in three health science schools in Chile. This cross-sectional study surveyed 284 students and faculty members from the dental, physical therapy and speech therapy schools of the University of Talca, Chile. A validated 15-question questionnaire about negative stereotypes was used (CENVE). The questions were divided into three categories: (i) health, (ii) social factors and motivation and (iii) character and personality. The scores for each category were grouped into the following categories: (i) positive, (ii) neutral and (iii) negative. Negative stereotypes were compared across genders, socio-economic status levels, classes, positions (student or faculty member) and schools. The majority of the participants held neutral stereotypes towards ageing, followed by positive perceptions. No differences were detected between the genders, schools or classes. While most of the students had neutral perceptions about ageing, the faculty's perceptions were rather positive (p = 0.0182). In addition, people of lower-middle socio-economic status held more positive stereotypes about ageing than the participants of high and middle status (p = 0.0496). Stereotypes about ageing held by health-related students and faculty members appear to be rather neutral. The stereotypes seem to be better among students with some clinical experience, students of lower socio-economic status and faculty members. © 2013 John Wiley & Sons A/S and The Gerodontology Society. Published by John Wiley & Sons Ltd.

  19. Effect of different transplanting leaf age on rice yield, nitrogen utilization efficiency and fate of 15N-fertilizer

    International Nuclear Information System (INIS)

    Fan Hongzhu; Lu Shihua; Zeng Xiangzhong

    2010-01-01

    Field experiments were conducted to study rice yield, N uptake and fate by using 15 N-urea at transplanting leaf age of 2-, 4-and 6-leaf, respectively. The results showed that rice yield significantly decreased with delay of transplanting leaf age, and 15 N-fertilizer uptake by grain and straw of rice, nitrogen utilization and residue also decreased, but loss of 15 N-fertilizer increased. Under different transplanting leaf age, N absorption by rice mainly came from the soil. Almost 1/3 of total N was supplied by fertilizer, and 2/3 came from soil. The efficiency of fertilizer was 20.8% ∼ 25.7%, 15 N-fertilizer residue ratio was 17.9% ∼ 32.2%, and 15 N-fertilizer loss was 42.1% ∼ 61.3%. 15 N-fertilizer residue mainly distributed in 0 ∼ 20 cm top soil under different treatments. The results indicated that transplanting young leaf age could increase rice yield and nitrogen utilization efficiency, and decrease loss of nitrogen fertilizer and pollution level on environment. (authors)

  20. Trends in Second-Hand Tobacco Smoke Exposure Levels at Home among Viet Nam School Children Aged 13-15 and Associated Factors.

    Science.gov (United States)

    Lam, Nguyen Tuan; Nga, Pham Thi Quynh; Minh, Hoang Van; Giang, Kim Bao; Hai, Phan Thi; Huyen, Doan Thu; Linh, Nguyen Thuy; Van, Duong Khanh; Khue, Luong Ngoc

    2016-01-01

    Second-hand tobacco smoke (SHS) exposure at home, especially among children, is a serious issue in Viet Nam. During the past decade, much effort has been taken for tobacco control in the country, including various prgorammes aiming to reduce SHS exposure among adults and children. This article analysed trends and factors associated with SHS exposure at home among school children aged 13-15 in Viet Nam, using the Global Youth Tobacco Surveys conducted in 2007 and 2014. Descriptive and inferential statistical methods with logistic regression were applied. Overall, there was a significant reduction in the level of exposure, from 58.5% (95%CI: 57.6-59.3) in 2007 to 47.1% (95%CI: 45.4-48.8) in 2014. Of the associated factors, having one or both parents smoking was significantly associated with the highest odds of SHS exposure at home (OR=5.0; 95%CI: 4.2-6.1). Conversely, having a mother with a college or higher education level was found to be a protective factor (OR=0.5; 95%CI: 0.3-0.8).

  1. LEGO-based Robotics in Higher Education: 15 Years of Student Creativity

    Directory of Open Access Journals (Sweden)

    Ethan Danahy

    2014-02-01

    Full Text Available Our goal in this article is to reflect on the role LEGO robotics has played in college engineering education over the last 15 years, starting with the introduction of the RCX in 1998 and ending with the introduction of the EV3 in 2013. By combining a modular computer programming language with a modular building platform, LEGO Education has allowed students (of all ages to become active leaders in their own education as they build everything from animals for a robotic zoo to robots that play children's games. Most importantly, it allows all students to develop different solutions to the same problem to provide a learning community. We look first at how the recent developments in the learning sciences can help in promoting student learning in robotics. We then share four case studies of successful college-level implementations that build on these developments.

  2. Text-Message Abbreviations and Language Skills in High School and University Students

    Science.gov (United States)

    De Jonge, Sarah; Kemp, Nenagh

    2012-01-01

    This study investigated the use of text-message abbreviations (textisms) in Australian adolescents and young adults, and relations between textism use and literacy abilities. Fifty-two high school students aged 13-15 years, and 53 undergraduates aged 18-24 years, all users of predictive texting, translated conventional English sentences into…

  3. Maine DOT Research Peer Exchange : June 13-15, 2017

    Science.gov (United States)

    2017-10-13

    On June 13 15, 2017 the Maine Department of Transportation hosted a research peer exchange to promote the research program within the department, provide a mechanism for sharing research management ideas amongst the team members, identify opportun...

  4. Swiss Adolescents' Career Aspirations: Influence of Context, Age, and Career Adaptability

    Science.gov (United States)

    Hirschi, Andreas

    2010-01-01

    This study investigated the content, realism, stability, and coherence of the career aspirations of 262 students in seventh grade in Switzerland (ages 13-15 years). The content analysis revealed that 82% of the participants named at least one realistic career aspiration, and aspirations showed clear resemblance to existing opportunities in the…

  5. An Educational Way of Dealing with Tunneling, Motivation to Novelties, and Creative Mindies in 13-16 Years of Age.

    Science.gov (United States)

    Laasonen, Raimo J.

    The objective of this study was to inquire if tunneling of mind, motivation to novelties, and creative mindies in 4 age groups (13, 14, 15, and 16, years of age) have dynamic relationships. A creative mindy is a new organized mind shape not previously occurring. The subjects were 93 pupils of a secondary comprehensive school. Questionnaires were…

  6. Optimization Technique With Sensitivity Analysis On Menu Scheduling For Boarding School Student Aged 13-18 Using “Sufahani-Ismail Algorithm”

    Science.gov (United States)

    Sudin, Azila M.; Sufahani, Suliadi

    2018-04-01

    Boarding school student aged 13-18 need to eat nutritious meals which contains proper calories, vitality and nutrients for appropriate development with a specific end goal to repair and upkeep the body tissues. Furthermore, it averts undesired diseases and contamination. Serving healthier food is a noteworthy stride towards accomplishing that goal. However, arranging a nutritious and balance menu manually is convoluted, wasteful and tedious. Therefore, the aim of this study is to develop a mathematical model with an optimization technique for menu scheduling that fulfill the whole supplement prerequisite for boarding school student, reduce processing time, minimize the budget and furthermore serve assortment type of food each day. It additionally gives the flexibility for the cook to choose any food to be considered in the beginning of the process and change any favored menu even after the ideal arrangement and optimal solution has been obtained. This is called sensitivity analysis. A recalculation procedure will be performed in light of the ideal arrangement and seven days menu was produced. The data was gathered from the Malaysian Ministry of Education and schools authorities. Menu arranging is a known optimization problem. Therefore Binary Programming alongside optimization technique and “Sufahani-Ismail Algorithm” were utilized to take care of this issue. In future, this model can be implemented to other menu problem, for example, for sports, endless disease patients, militaries, colleges, healing facilities and nursing homes.

  7. Is Article 13 of “ Educational Directive for Gifted and Talented Students in Universities” a valid rule?

    Directory of Open Access Journals (Sweden)

    Oveisgharan Sh

    2003-07-01

    Full Text Available Background: Iranian talented university students who take semester averages below 17 for at most two times can't use facilities provided for Gifted and Talented students in Universities through Ministry of Health (MOH directive regarding gifted and talented student. Purpose: To examine the validity of article 13 of this directive. Methods: Renzulli's three ring concept of giftedness was chosen as giftedness definition. Obtaining Grade Point Averages equal or more than 15 was regarded as "above average ability". A questionnaire, based on “Scales for Rating the Behavioural Characteristics of Superior Students” was designed for "creativity" and "task commitment" evaluation. Score 3.00 or more in "creativity" and "task commitment" evaluation was regarded to be sufficient to keep the student in the program. Students who were admitted in Isfahan University of Medical Sciences during 1997-1999 and recognized as gifted initially by MOH were included in our study. Results: 147 students were included in this study, of which 50% were female. From the study group, 20 student reports, done by 39 students were evaluated. Of these 39 students, 31 would have been left out based on article. Out of 31 students, 18 met all three criteria of Renzulli's definition. Conclusion: There may be gifted student who are denied the opportunity of using the facilities provided for gifted student based on enforcement of article 13 of IGCT directive. Further study to devise better measure for identification of gifted student seems to be warranted. Keywords: GIFTED, IDENTIFICATION, ISFAHAN UNIVERSITY OF MEDICAL SCIENCES

  8. Less Interested after Lessons? Report on a Small-Scale Research Study into 12- to 13-Year-Old Students' Attitudes to Earth Science

    Science.gov (United States)

    Hetherington, Lindsay

    2010-01-01

    Results of a small-scale research study conducted with year 8 (ages 12-13) students suggest that although these students have generally positive attitudes towards earth science, girls tend to be less interested in it than boys. Interest in earth science was found to separate into two dominant factors, labelled "scientific" and…

  9. Violência e atividade sexual desprotegida em adolescentes menores de 15 anos Violence and unsafe sexual activity of adolescents under 15 years of age

    Directory of Open Access Journals (Sweden)

    Sérgio Araujo Martins Teixeira

    2010-01-01

    Full Text Available OBJETIVO: Identificar fatores associados à atividade sexual desprotegida em adolescentes femininas menores de 15 anos. MÉTODOS: Estudo observacional de corte transversal com adolescentes femininas menores de 15 anos e sexualmente ativas, atendidas em um ambulatório público de ginecologia. Os instrumentos de coleta de dados foram: entrevista semiestruturada para dados pessoais e de sexualidade, e exame clínico-laboratorial para diagnóstico de doenças sexualmente transmissíveis. Os dados foram analisados por meio de testes de frequência, de associação de variáveis com p OBJECTIVE: To identify factors associated with unprotected sexual activity in female adolescents younger than 15 years. METHODS: Observational cross-sectional trial with female teenagers less than 15 years-old and sexually active, attended at a public gynecology clinic. Instruments for data collection were: semi-structured interviews for personal data and about sexuality as well as clinical examination and laboratory tests for diagnosis of sexually transmitted diseases. Data were analyzed by testing of frequency, association of variables with p <0.05 and multiple correspondence analysis. RESULTS: One hundred adolescents between 11 and 14 years of age sexually active were interviewed and examined, 71% declared themselves black, one-third were behind in school, 80% began sexual activity before 13 years of age , 58% reported having been victims of violence in the intrafamily environment and 13% had suffered sexual abuse, 77% did not use condoms regularly and 22% had STDs. Unprotected sexual activity occurred more frequently with the first sexual intercourse before 13 years of age, commercial sexual exploitaion, multiple sexual partners, intrafamily violence and school delay, in addition to be black, to unexpected pregnancy and have STDs. CONCLUSION: The multiple violence suffered by teenagers, including structural, intrafamily and sexual, contribute to increase their

  10. A 13-hour laboratory school study of lisdexamfetamine dimesylate in school-aged children with attention-deficit/hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Childress Ann C

    2009-06-01

    Full Text Available Abstract Background Lisdexamfetamine dimesylate (LDX is indicated for the treatment of attention-deficit/hyperactivity disorder (ADHD in children 6 to 12 years of age and in adults. In a previous laboratory school study, LDX demonstrated efficacy 2 hours postdose with duration of efficacy through 12 hours. The current study further characterizes the time course of effect of LDX. Methods Children aged 6 to 12 years with ADHD were enrolled in a laboratory school study. The multicenter study consisted of open-label, dose-optimization of LDX (30, 50, 70 mg/d, 4 weeks followed by a randomized, placebo-controlled, 2-way crossover phase (1 week each. Efficacy measures included the SKAMP (deportment [primary] and attention [secondary] and PERMP (attempted/correct scales (secondary measured at predose and at 1.5, 2.5, 5, 7.5, 10, 12, and 13 hours postdose. Safety measures included treatment-emergent adverse events (AEs, physical examination, vital signs, and ECGs. Results A total of 117 subjects were randomized and 111 completed the study. Compared with placebo, LDX demonstrated significantly greater efficacy at each postdose time point (1.5 hours to 13.0 hours, as measured by SKAMP deportment and attention scales and PERMP (P Conclusion In school-aged children (6 to 12 years with ADHD, efficacy of LDX was maintained from the first time point (1.5 hours up to the last time point assessed (13.0 hours. LDX was generally well tolerated, resulting in typical stimulant AEs. Trial registration Official Title: A Phase IIIb, Randomized, Double-Blind, Multi-Center, Placebo-Controlled, Dose-Optimization, Cross-Over, Analog Classroom Study to Assess the Time of Onset of Vyvanse (Lisdexamfetamine Dimesylate in Pediatric Subjects Aged 6–12 With Attention-Deficit/Hyperactivity Disorder. ClinicalTrials.gov Identifier: NCT00500149 http://clinicaltrials.gov/ct2/show/NCT00500149

  11. 1H, 13C and 13N chemical shifts and 1H-15N and 13C-15N heteronuclear spin-spin coupling constants n the NMR spectra of 5-substituted furfural oximes

    International Nuclear Information System (INIS)

    Popelis, Yu.Yu.; Liepin'sh, E.E.; Lukevits, E.Ya.

    1986-01-01

    The 1 H, 13 C, and 15 N NMR spectra of 15 N-enriched 5-substituted furfural oximes were investigated. It was shown that the chemical shifts of the ring atoms and the oxime group correlate satisfactorily with the F and R substituent constants, whereas their sensitivity to the effect of the substituents is lower than in monosubstituted furan derivatives. The constants of spin-spin coupling between the ring protons and the oxime group were determined. An analysis of the 1 H- 1 H spin-spin coupling constants (SSCC) on the basis of their stereospecificity indicates that the E isomers have primarily an s-trans conformation in polar dimethyl sulfoxide, whereas the Z isomers, on the other hand, have an s-cis conformation. The signs of the direct and geminal 13 C- 15 N SSCC were determined for 5-trimethylsilylfurfural oxime

  12. Relative Age Effect in Physical Fitness Among Elementary and Junior High School Students.

    Science.gov (United States)

    Nakata, Hiroki; Akido, Miki; Naruse, Kumi; Fujiwara, Motoko

    2017-10-01

    The present study investigated characteristics of the relative age effect (RAE) among a general sample of Japanese elementary and junior high school students. Japan applies a unique annual age-grouping by birthdates between April 1 and March 31 of the following year for sport and education. Anthropometric and physical fitness data were obtained from 3,610 Japanese students, including height, weight, the 50-m sprint, standing long jump, grip strength, bent-leg sit-ups, sit and reach, side steps, 20-m shuttle run, and ball throw. We examined RAE-related differences in these data using a one-way analysis of variance by comparing students with birthdates in the first (April-September) versus second (October-March of the following year) semesters. We observed a significant RAE for boys aged 7 to 15 years on both anthropometric and fitness data, but a significant RAE for girls was only evident for physical fitness tests among elementary school and not junior high school students. Thus, a significant RAE in anthropometry and physical fitness was evident in a general sample of school children, and there were RAE gender differences among adolescents.

  13. Tobacco use and second-hand smoke exposure in young adolescents aged 12-15 years: data from 68 low-income and middle-income countries.

    Science.gov (United States)

    Xi, Bo; Liang, Yajun; Liu, Yunxia; Yan, Yinkun; Zhao, Min; Ma, Chuanwei; Bovet, Pascal

    2016-11-01

    Tobacco use is an important risk factor for non-communicable diseases worldwide. However, the global extent and prevalence of tobacco use in adolescents is poorly described. Using previously collected survey data, we aimed to assess tobacco use and second-hand smoke exposure in young adolescents aged 12-15 years in 68 low-income and middle-income countries. We used data from the Global School-based Student Health Survey (2006-13) and the China Global Tobacco Youth Survey (2013), which are school-based surveys of young adolescents aged 12-15 years that assess health behaviours using a standardised, anonymous, self-reported questionnaire. We calculated the prevalence of current tobacco use and exposure to second-hand smoke in young adolescents from 68 low-income and middle-income countries that collected these data in the surveys. We used a multilevel model to estimate the association between parental tobacco use, second-hand smoke, and adolescent tobacco use, adjusting for sex, age, school, school class, country's purchasing power parity, smoking initiation age, national prevalence of tobacco use among adults, year the WHO FCTC was ratified for each country, proxy of socioeconomic status, and survey year. The mean prevalence of current tobacco use was 13·6%, ranging from 2·8% in Tajikistan to 44·7% in Samoa. In most countries, the prevalence of tobacco use was higher for boys than girls, and higher for adolescents aged 14-15 years than for those aged 12-13 years. The overall prevalence of second-hand smoke exposure was 55·9%, ranging from 16·4% in Tajikistan to 85·4% in Indonesia. Parental tobacco use (as reported by the young adolescents), especially maternal use, was associated with tobacco use in young adolescents (odds ratio 2·06, 95% CI 1·93-2·19, for maternal and 1·29, 1·23-1·35 for paternal use). Second-hand smoke exposure was also a risk factor for young adolescents' tobacco use (2·56, 2·43-2·69). However, the prevalence of tobacco use was not

  14. 15 CFR 10.13 - Withdrawal of a published standard.

    Science.gov (United States)

    2010-01-01

    ...) Before withdrawing a standard published under these procedures, the Director will review the relative... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Withdrawal of a published standard. 10... DEVELOPMENT OF VOLUNTARY PRODUCT STANDARDS § 10.13 Withdrawal of a published standard. (a) Standards published...

  15. The Effects of Swedish Knife Model on Students' Understanding of the Digestive System

    Science.gov (United States)

    Cerrah Ozsevgec, Lale; Artun, Huseyin; Unal, Melike

    2012-01-01

    This study was designed to examine the effect of Swedish Knife Model on students' understanding of digestive system. A simple experimental design (pretest-treatment-posttest) was used in the study and internal comparison of the results of the one group was made. The sample consisted of 40 7th grade Turkish students whose ages range from 13 to 15.…

  16. Reproducibility of a web-based FFQ for 13- to 15-year-old Danish adolescents

    DEFF Research Database (Denmark)

    Bjerregaard, Anne A.; Tetens, Inge; Olsen, Sjurdur F.

    2016-01-01

    the DNBC. Adolescents aged 13 to 15 years old (n 48, 60 % girls) completed the FFQ twice 4 weeks apart. The proportion of adolescents consistently classified into the same tertile according to amount of food intake ranged from 45 % (fish) to 77 % (vegetables), whereas classification into opposite tertiles......FFQ are widely used in large-scale studies to assess dietary intake. To aid interpretation of diet-disease associations assessment of validity must be performed. Reproducibility is one aspect of validity focusing on the stability of repeated assessment with the same method which may also reveal...... ranged from 0 % (fruit, oils and dressing) to 15 % (beverages). Overall, no significant differences were observed in intake of food groups or nutrients between the two completions of the FFQ. Mean crude Spearman correlation for all food groups was 0·56 and mean intra-class correlation for all food groups...

  17. (13)C-(15)N correlation via unsymmetrical indirect covariance NMR: application to vinblastine.

    Science.gov (United States)

    Martin, Gary E; Hilton, Bruce D; Blinov, Kirill A; Williams, Antony J

    2007-12-01

    Unsymmetrical indirect covariance processing methods allow the derivation of hyphenated 2D NMR data from the component 2D spectra, potentially circumventing the acquisition of the much lower sensitivity hyphenated 2D NMR experimental data. Calculation of HSQC-COSY and HSQC-NOESY spectra from GHSQC, COSY, and NOESY spectra, respectively, has been reported. The use of unsymmetrical indirect covariance processing has also been applied to the combination of (1)H- (13)C GHSQC and (1)H- (15)N long-range correlation data (GHMBC, IMPEACH, or CIGAR-HMBC). The application of unsymmetrical indirect covariance processing to spectra of vinblastine is now reported, specifically the algorithmic extraction of (13)C- (15)N correlations via the unsymmetrical indirect covariance processing of the combination of (1)H- (13)C GHSQC and long-range (1)H- (15)N GHMBC to produce the equivalent of a (13)C- (15)N HSQC-HMBC correlation spectrum. The elimination of artifact responses with aromatic solvent-induced shifts (ASIS) is shown in addition to a method of forecasting potential artifact responses through the indirect covariance processing of the GHSQC spectrum used in the unsymmetrical indirect covariance processing.

  18. Legal-Age Students' Provision of Alcohol to Underage College Students: An Exploratory Study

    Science.gov (United States)

    Brown, Richard L.; Matousek, Therese A.; Radue, Mary B.

    2009-01-01

    Objective: The authors investigated the magnitude and cultural context of legal-age university students' provision of alcohol to underage students and how such alcohol provision might be deterred. Participants: 130 legal-age students at a midwestern university in the United States were randomly selected. Methods: The authors assessed 16 focus…

  19. Immigrant Status, Gender, and School Burnout in Finnish Lower Secondary School Students: A Longitudinal Study

    Science.gov (United States)

    Salmela-Aro, Katariina; Read, Sanna; Minkkinen, Jaana; Kinnunen, Jaana M.; Rimpelä, Arja

    2018-01-01

    The aim of this longitudinal study among 9223 students from grade 7 and grade 9 (age 13-14 and 15-16) was to assess whether immigrant status and gender are associated with the level and change (slope) in school burnout among lower secondary school students in the Helsinki metropolitan area. Ninety-seven percent of the variation in school burnout…

  20. [Active and passive smoking--attitudes and opinion of the students].

    Science.gov (United States)

    Kostić-Bibić, Nada; Dragas, Zorica V; Vukmirović, Vesna; Pinter, Snezana

    2006-10-01

    The concern is present worldwide as the tobacco use and smoking is becoming more and more common in young generation. Spread of tobacco use epidemics is a global problem with serious consequences to social, economic and ecological life a well as on health. To collect information about tobacco use in students aged 13-15 years in school in Subotica, their knowledge and standing about smoking as well as level of advertisement and availability of purchasing tobacco and tobacco products. It should include the level of passive smoking, i.e. exposure to tobacco smoke and health education in curriculum. Application of statistical study involving 327 students aged 13-15 years in 4 elementary and 2 high schools in Subotica, in October 2003. "Global youth tobacco survey" was the statistical study that was used after required permits had been granted. A total of 41.5% of students tried cigarette smoking, more girls (43.4%) than boys (38.6%; p > 0.05); 52.6% of first grade of high school students, 37.6% of eighth grade and 33.9% seventh grade students (X2 = 9.081; DF = 2; p media, and cigarettes are available easily. The level of passive smoking was also very high: 24.8% of parents were smokers, i.e. fathers accounted for 23.2%, and mothers accounted for 17% of cases. 28.7% of teachers smoked in school building. Educational and health programs in the schools are not satisfactory. The research shows that the use of tobacco products in student population is serious. It seems necessary to make an effective program which will control the use of tobacco products in early age of student population.

  1. Age at menarche in Polish University students born before, during and after World War II: Economic effects.

    Science.gov (United States)

    Liczbińska, Grażyna; Czapla, Zbigniew; Piontek, Janusz; Malina, Robert M

    2018-02-01

    Although the relationships between economic conditions and biological variables over the past two centuries in Poland are reasonably well-documented, the influence of economic and political disruptions, including nutritional privation, during the years immediately before, during and shortly after World War II (WWII) has received less attention. This paper considers the association between age at menarche and body size of university students born before, during and after WWII and father's level of education, a commonly used indicator of family economic status in Poland. Subjects were 518 university students surveyed between 1955 and 1972, birth years 1931 through 1951. The sample was divided into three birth cohorts: before (n=237), during (n=247) and after (n=34) WWII. Age at menarche was compared among birth cohorts, and by weight status and father's level of education. Age at menarche increased slightly but significantly among women born during WWII (14.4 yrs) compared to those born before (14.2 yrs) and after (13.9 yrs) the war. Controlling for year of birth and age of the student, age at menarche was significantly earlier in overweight (13.42±0.35 yrs) than in normal weight (14.33±0.06 yrs) and thin (14.54±0.21 yrs) women. Adjusted mean ages at menarche in small samples of overweight women did not differ by father's level of education, and were earlier than corresponding ages of thin and normal weight women. Adjusted mean ages at menarche did not differ between thin and normal weight women with fathers having primary or no education, but were slightly later in thin than in normal weight women with fathers having a vocational, secondary or higher education. Although age at menarche was associated with father's level of education, young adult weight status was a somewhat more important correlate. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. School and work status, drug-free workplace protections, and prescription drug misuse among Americans ages 15-25.

    Science.gov (United States)

    Miller, Ted; Novak, Scott P; Galvin, Deborah M; Spicer, Rebecca S; Cluff, Laurie; Kasat, Sandeep

    2015-03-01

    We assessed the prevalence and characteristics of prescription drug misuse among youth ages 15-25 to examine differences by student and employment status, and associations with workplace antidrug policies and programs. Multivariate logistic regressions analyzed associations in weighted data on the 20,457 young adults in the combined 2004-2008 National Surveys on Drug Use and Health. Demographic controls included sex, race, community size, and age group. After we accounted for demographic controls, at ages 15-25, students were less likely than nonstudents to misuse prescription drugs. Segmenting student from nonstudent groups, working consistently was associated with a further reduction in misuse for those ages 18-25. When we controlled for demographics and substance use history, both Employee Assistance Program (EAP) services and awareness that one's employer had a drug-free workplace policy were associated with significantly lower misuse of prescription drugs (OR = 0.85 for each program, 95% CI [0.73, 1.00] and [0.72, 1.00]). Associations of workplace antidrug policies and programs with marijuana use and with Diagnostic and Statistical Manual for Mental Disorders, Fourth Edition, criteria for alcohol abuse and dependence contrasted sharply with these patterns. All four aspects were significantly associated with lower marijuana use. None was associated with problem drinking. Protective effects of drug-free workplace policy and EAPs persist after other substance use was controlled for. Comparing the effects of workplace programs on illicit drug use and problem drinking versus prescription misuse suggests that those protective associations do not result from selection bias. Thus, drug-free workplace policies and EAPs appear to help protect younger workers against prescription misuse. If workplace substance use disorder programs focused prevention messages and interventions on prescription drug misuse, their impact on misuse might increase.

  3. Prevalence of periodontitis among the adolescents aged 15-18 years in Mangalore City: An epidemiological and microbiological study

    Directory of Open Access Journals (Sweden)

    K Pallavi Nanaiah

    2013-01-01

    Full Text Available Background: Periodontitis is a group of inflammatory diseases affecting the supporting tissues of the tooth. Both aggressive periodontitis (AP and chronic periodontitis (CP have a multifactorial etiology, with dental plaque as the initiating factor. However, the initiation and progression of periodontitis are influenced by other factors including microbiologic, social and behavioral and systemic and genetic factors. The prevalence of periodontal diseases varies in different regions of the world according to the definition of periodontitis and the study population, and there are indications that they may be more prevalent in developing than in developed countries. Materials and Methods: A cross-sectional study was conducted among the adolescents of 15-18 years of age in Mangalore City. One thousand one hundred students aged 15-18 years were selected for the study from the schools and colleges in Mangalore City using a convenient sampling method. The prevalence of AP and CP were assessed in the study using a community periodontal index. Students who were diagnosed clinically and radiographically were subjected to microbiological examination to confirm AP. Results: A high prevalence of gingivitis and periodontitis was found in students belonging to the lower socioeconomic status group compared with the higher socioeconomic groups, which were associated with poor oral hygiene habits. The prevalence of AP was found to be 0.36% and that of CP was found to be 1.5%. Conclusion: Oral diseases have a significant impact on the social and psychological aspects of an individual′s life. Exposure to risk factors, such as age, low socio-economic status, poor education, low dental care utilization, poor oral hygiene levels, smoking, psychosocial stress and genetic factors are significantly associated with an increased risk of periodontitis among adolescents. Although genetic factors play a major role in periodontitis, the treatment outcome will still be

  4. The Perceived Impact of Playing Music while Studying: Age and Cultural Differences

    Science.gov (United States)

    Kotsopoulou, Anastasia; Hallam, Susan

    2010-01-01

    Rating scale questionnaires were administered to 600 students in three age groups, 12-13, 15-16 and 20-21 from Japan, the UK, Greece and the USA. The questionnaires explored the extent of playing music while studying, the kinds of tasks when music was played, the perceived effects of music on studying, the characteristics and types of music played…

  5. Physical activity level of school children of age 10-13 years

    OpenAIRE

    Ronghe, Dr. Rashmi N; Gotmare, Dr. Neha A; Kawishwar, Dr. Shraddha

    2016-01-01

    Aim: To assess physical activity level of school children of age 10-13 years.Objectives: To assess and grade physical activity level in children of age 10-13 years using Physical Activity Questionnaire for Children (PAQ-C) classified into: Light Physical activity; Moderate Physical activity; Moderate to vigorous Physical activity and High Physical activity.Methodology: This is Questionnaire based survey study which was conducted on 100 school going children of 10-13 years who were present on ...

  6. Oncolysis of malignant human melanoma tumors by Coxsackieviruses A13, A15 and A18

    Directory of Open Access Journals (Sweden)

    Barry Richard D

    2011-01-01

    Full Text Available Abstract Many RNA viruses are displaying great promise in the field of oncolytic virotherapy. Previously, we reported that the picornavirus Coxsackievirus A21 (CVA21 possessed potent oncolytic activity against cultured malignant melanoma cells and melanoma xenografts in mice. In the present study, we demonstrate that three additional Group A Coxsackieviruses; Coxsackievirus A13 (CVA13, Coxsackievirus A15 (CVA15 and Coxsackievirus A18 (CVA18, also have similar oncolytic activity against malignant melanoma. Each of the viruses grew quickly to high titers in cancer cells expressing ICAM-1 and intratumoral injection of preformed subcutaneous SK-Mel-28 xenografts in mice with CVA13, CVA15 and CVA18 resulted in significant tumor volume reduction. As preexisting immunity could potentially hinder oncolytic virotherapy, sera from stage IV melanoma patients and normal controls were tested for levels of protective antibody against the panel of oncolytic Coxsackieviruses. Serum neutralization assays revealed that 3 of 21 subjects possessed low levels of anti-CVA21 antibodies, while protective antibodies for CVA13, CVA15 and CVA18 were not detected in any sample. Serum from individuals who were seropositive for CVA21 failed to exhibit cross-neutralization of CVA13, CVA15 and CVA18. From these studies it can be concluded that the administration of CVA13, CVA15 or CVA18 could be employed as a potential multivalent oncolytic therapy against malignant melanoma.

  7. Risk assessment of medically assisted reproduction and advanced maternal ages in the development of Prader-Willi syndrome due to UPD(15)mat.

    Science.gov (United States)

    Matsubara, K; Murakami, N; Fukami, M; Kagami, M; Nagai, T; Ogata, T

    2016-05-01

    Recent studies have suggested that disomic oocyte-mediated uniparental disomy 15 (UPD(15)mat) is increased in patients with Prader-Willi syndrome (PWS) born after medically assisted reproduction (MAR). However, it remains unknown whether the increase is primarily due to MAR procedure itself or advanced maternal childbearing ages as a predisposing factor for the disomic oocyte production. To examine this matter, we studied 122 naturally conceived PWS patients (PWS-NC group) and 13 MAR-conceived patients (PWS-MAR group). The relative frequency of disomic oocyte-mediated UPD(15)mat was significantly higher in PWS-MAR group than in PWS-NC group (7/13 vs 20/122, p = 0.0045), and the maternal childbearing ages were significantly higher in PWS-MAR group than in PWS-NC group [median (range), 38 (26-45) vs 30 (19-42), p = 0.0015]. However, the logistic regression analysis revealed no significant association between the occurrence of disomic oocyte-mediated UPD(15)mat and MAR, after adjusting for childbearing age (p = 0.25). Consistent with this, while the frequency of assisted reproductive technology (ART)-conceived livebirths was higher in the PWS patients than in the Japanese general population (6.4% vs 1.1%, p = 0.00018), the distribution of childbearing ages was significantly skewed to the increased ages in the PWS patients (p < 2.2 × 10(-16) ). These results argue against a positive association of MAR procedure itself with the development of UPD(15)mat. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  8. High rates of de novo 15q11q13 inversions in human spermatozoa

    Directory of Open Access Journals (Sweden)

    Molina Òscar

    2012-02-01

    Full Text Available Abstract Low-Copy Repeats predispose the 15q11-q13 region to non-allelic homologous recombination. We have already demonstrated that a significant percentage of Prader-Willi syndrome (PWS fathers have an increased susceptibility to generate 15q11q13 deletions in spermatozoa, suggesting the participation of intrachromatid exchanges. This work has been focused on assessing the incidence of de novo 15q11q13 inversions in spermatozoa of control donors and PWS fathers in order to determine the basal rates of inversions and to confirm the intrachromatid mechanism as the main cause of 15q11q13 anomalies. Semen samples from 10 control donors and 16 PWS fathers were processed and analyzed by triple-color FISH. Three differentially labeled BAC-clones were used: one proximal and two distal of the 15q11-q13 region. Signal associations allowed the discrimination between normal and inverted haplotypes, which were confirmed by laser-scanning confocal microscopy. Two types of inversions were detected which correspond to the segments involved in Class I and II PWS deletions. No significant differences were observed in the mean frequencies of inversions between controls and PWS fathers (3.59% ± 0.46 and 9.51% ± 0.87 vs 3.06% ± 0.33 and 10.07% ± 0.74. Individual comparisons showed significant increases of inversions in four PWS fathers (P Results suggest that the incidence of heterozygous inversion carriers in the general population could reach significant values. This situation could have important implications, as they have been described as predisposing haplotypes for genomic disorders. As a whole, results confirm the high instability of the 15q11-q13 region, which is prone to different types of de novo reorganizations by intrachromatid NAHR.

  9. 1H, 15N and 13C NMR Assignments of Mouse Methionine Sulfoxide Reductase B2

    Science.gov (United States)

    Breivik, Åshild S.; Aachmann, Finn L.; Sal, Lena S.; Kim, Hwa-Young; Del Conte, Rebecca; Gladyshev, Vadim N.; Dikiy, Alexander

    2011-01-01

    A recombinant mouse methionine-r-sulfoxide reductase 2 (MsrB2ΔS) isotopically labeled with 15N and 15N/13C was generated. We report here the 1H, 15N and 13C NMR assignments of the reduced form of this protein. PMID:19636904

  10. [A survey of HIV, HBV and HCV infections in children aged 1-13 years in Yi ethnic area, Sichuan province].

    Science.gov (United States)

    Yang, Y; Zhou, Y B; Cheng, W T; Pan, X; Song, X X; Jiang, Q W

    2017-09-10

    Objective: To investigate the prevalence of HIV, HBV and HCV infections in children aged 1-13 years in Yi ethnic area in Sichuan province. Methods: A cross-sectional study was conducted in the form of field survey in four townships selected from Yi ethnic area of Sichuan during 2014-2015. Participants were children aged 1-13 years by sample size of 900 and were screened for HIV antibody, HBV surface antigen and HCV antibody, and laboratory comfirmation was conducted. The area, age, gender and ethnic group specific infection rates were compared by using Fisher's exact test, and multiple comparisons were corrected by using Bonferroni correction. Results: A total of 677 children aged 1-13 years were surveyed. The infection rates of HIV, HBV and HCV were 1.03 % (7/677, 95 %CI : 0.42 % -1.12 % ), 6.65 % (45/677, 95 %CI : 4.89 % -8.79 % ) and 0.15 % (1/677, 95 %CI : 0 % -0.82 % ), respectively. The infection rates of HIV differed among townships ( P =0.000), the infection rate was higher in township D than in township B, the difference was significant ( P HBV and HCV infections were not significant among different townships, age, gender and ethnic groups. The difference in HBV viral load between age group 5-9 years and age groups 10-13 years was not significant ( U =115.000, P =0.967). Conclusions: The burden of HIV and HBV infections in children aged 1-13 years was heavy in rural area of Yi ethnic area in Sichuan. Therefore, it is necessary to take effective measures to block the vertical transmission of HIV and HBV as well as to increase the coverage of HBV vaccination.

  11. Preferential Generation of 15-HETE-PE Induced by IL-13 Regulates Goblet Cell Differentiation in Human Airway Epithelial Cells.

    Science.gov (United States)

    Zhao, Jinming; Minami, Yoshinori; Etling, Emily; Coleman, John M; Lauder, Sarah N; Tyrrell, Victoria; Aldrovandi, Maceler; O'Donnell, Valerie; Claesson, Hans-Erik; Kagan, Valerian; Wenzel, Sally

    2017-12-01

    Type 2-associated goblet cell hyperplasia and mucus hypersecretion are well known features of asthma. 15-Lipoxygenase-1 (15LO1) is induced by the type 2 cytokine IL-13 in human airway epithelial cells (HAECs) in vitro and is increased in fresh asthmatic HAECs ex vivo. 15LO1 generates a variety of products, including 15-hydroxyeicosatetraenoic acid (15-HETE), 15-HETE-phosphatidylethanolamine (15-HETE-PE), and 13-hydroxyoctadecadienoic acid (13-HODE). In this study, we investigated the 15LO1 metabolite profile at baseline and after IL-13 treatment, as well as its influence on goblet cell differentiation in HAECs. Primary HAECs obtained from bronchial brushings of asthmatic and healthy subjects were cultured under air-liquid interface culture supplemented with arachidonic acid and linoleic acid (10 μM each) and exposed to IL-13 for 7 days. Short interfering RNA transfection and 15LO1 inhibition were applied to suppress 15LO1 expression and activity. IL-13 stimulation induced expression of 15LO1 and preferentially generated 15-HETE-PE in vitro, both of which persisted after removal of IL-13. 15LO1 inhibition (by short interfering RNA and chemical inhibitor) decreased IL-13-induced forkhead box protein A3 (FOXA3) expression and enhanced FOXA2 expression. These changes were associated with reductions in both mucin 5AC and periostin. Exogenous 15-HETE-PE stimulation (alone) recapitulated IL-13-induced FOXA3, mucin 5AC, and periostin expression. The results of this study confirm the central importance of 15LO1 and its primary product, 15-HETE-PE, for epithelial cell remodeling in HAECs.

  12. Experiments and strategies for the assignment of fully13 C/15N-labelled polypeptides by solid state NMR

    International Nuclear Information System (INIS)

    Straus, Suzana K.; Bremi, Tobias; Ernst, Richard R.

    1998-01-01

    High-resolution heteronuclear NMR correlation experiments and strategies are proposed for the assignment of fully 13 C/ 15 N-labelled polypeptides in the solid state. By the combination of intra-residue and inter-residue 13 C- 15 N correlation experiments with 13 C- 13 C spin-diffusion studies, it becomes feasible to partially assign backbone and side-chain resonances in solid proteins. The performance of sequences using 15 N instead of 13 C detection is evaluated regarding sensitivity and resolution for a labelled dipeptide (L-Val-L-Phe). The techniques are used for a partial assignment of the 15 N and 13 C resonances in human ubiquitin

  13. Prader-Willi syndrome and atypical submicroscopic 15q11-q13 deletions with or without imprinting defects.

    Science.gov (United States)

    Hassan, Maaz; Butler, Merlin G

    2016-11-01

    We report a 20 year follow up on a Caucasian female, now 26 years of age, with Prader-Willi syndrome (PWS) harboring an atypical 15q11-q13 submicroscopic deletion of 100-200 kb in size first detected in 1996 involving the imprinting center, SNRPN gene and surrounding region. PWS is a rare complex disorder caused by the loss of paternally expressed genes in the 15q11-q13 region. With high resolution chromosomal microarray and methylation - specific MLPA analysis, we updated the genetic findings on our patient and found a 209,819bp deletion including the SNURF-SNRPN gene complex which includes the imprinting center and the SNORD116 region. We compared with four other similarly reported individuals in the literature with atypical submicroscopic deletions within this region but without imprinting center involvement to better characterize the specific genetic lesions causing PWS clinical findings. Clinically, our patient met the diagnostic criteria of PWS including infantile hypotonia, a poor suck with feeding difficulties, global developmental delays and later food foraging, childhood obesity, small hands and skin picking. Small atypical deletions of comparable sizes were seen in the 15q11-q13 region in all five cases and similar behavioral/physical characteristics were found despite an imprinting defect in our patient. These results further support an overlapping critical deletion region involving the non-coding snoRNA SNORD116 in common in the five individuals playing a key role in contributing to the PWS phenotype. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  14. Asthma Mortality Among Persons Aged 15-64 Years, by Industry and Occupation - United States, 1999-2016.

    Science.gov (United States)

    Patel, Opal; Syamlal, Girija; Wood, John; Dodd, Katelynn E; Mazurek, Jacek M

    2018-01-19

    In 2015, an estimated 18.4 million U.S. adults had current asthma, and 3,396 adult asthma deaths were reported (1). An estimated 11%-21% of asthma deaths might be attributable to occupational exposures (2). To describe asthma mortality among persons aged 15-64 years,* CDC analyzed multiple cause-of-death data † for 1999-2016 and industry and occupation information collected from 26 states § for the years 1999, 2003, 2004, and 2007-2012. Proportionate mortality ratios (PMRs) ¶ for asthma among persons aged 15-64 years were calculated. During 1999-2016, a total of 14,296 (42.9%) asthma deaths occurred among males and 19,011 (57.1%) occurred among females. Based on an estimate that 11%-21% of asthma deaths might be related to occupational exposures, during this 18-year period, 1,573-3,002 asthma deaths in males and 2,091-3,992 deaths in females might have resulted from occupational exposures. Some of these deaths might have been averted by instituting measures to prevent potential workplace exposures. The annual age-adjusted asthma death rate** per 1 million persons aged 15-64 years declined from 13.59 in 1999 to 9.34 in 2016 (pindustries and occupations underscores the importance of optimal asthma management and identification and prevention of potential workplace exposures.

  15. Mixed Age Grouping for Gifted Students.

    Science.gov (United States)

    Bouchard, Lorraine L.

    1991-01-01

    The application of mixed-age grouping at Rainard School (Houston, Texas), a private school for gifted students, is described. Discussed are advantages (such as encouraging cooperation instead of competition), the optimum age spread, the differentiated and individualized curriculum, parent reactions, teacher reactions, and difficulties. (DB)

  16. Prevalence of mental disorders in 6-16-year-old students in Sichuan province, China.

    Science.gov (United States)

    Qu, Yuan; Jiang, Hongyun; Zhang, Ni; Wang, Dahai; Guo, Lanting

    2015-05-13

    To investigate the point prevalence of mental disorders in school students, multistage cluster stratified random sampling and two-phase survey methods were used to identify 40 primary and middle schools. The students were screened using the Chinese version of the Child Behavior Checklist and diagnosed using the Mini International Neuropsychiatric Interview. The prevalence of behavioral problems was 19.13%. The prevalence of behavioral problems significantly differed by sex, age, city of residence, and caretaker. The six-month prevalence of any mental disorder was 15.24% (95% CI: 15.49%-16.97%). Psychiatric disorders were more prevalent in boys (17.33%) relative to girls (13.11%; p mental disorders significantly differed by community and caretaker, and 36.46% of students exhibited comorbidity. Results demonstrated important mental health issues, with a high incidence of comorbidities, in this population. Students' mental health requires increased attention, particularly in poverty-stricken areas and left-behind children and adolescents.

  17. Liaison amid problem behavior and traumatic dental injury among children aged 12-15 years in Bhopal

    OpenAIRE

    Naveen S Yadav; Vrinda Saxena; Manish Jain; Kapil Paiwal

    2015-01-01

    Introduction: Liaison amid problem behavior and traumatic dental injury among children aged 13-15 years are consequential due to multifactorial dental, orofacial skeletal, psycosocial behavior pattern. The probable etiology is been equated overjet; inadequate lip coverage is the major etiological factors accountable for traumatic dental injuries. Aims: The aim was to assess the relationship of problem behavior, type of lip coverage, and the size of overjet with the traumatic dental injury amo...

  18. Oral cleanliness of 12-13-year-old and 15-year-old school children of Sunsari District, Nepal

    Directory of Open Access Journals (Sweden)

    Yee R

    2006-09-01

    Full Text Available The aim of the study was to evaluate the oral cleanliness of school children in the District of Sunsari, Nepal. A multi-stage random sampling oral epidemiological survey was conducted in private and government, urban, rural town and rural village schools in 15 illakas of Sunsari District, Eastern Nepal. A total of 600, 12-13-year-old and 600 15-year-old school children were examined by trained examiners using the simplified oral hygiene index (OHI-S. The average age-group, debris and calculus index scores were combined to obtain the simplified oral hygiene index (OHI-S. The mean OHI-S scores were compared and evaluated using the parametric t-test for two independent samples. The mean OHI-S for urban 12-13-year-old school children was 0.98 compared to 1.34 for school children of rural towns and 1.44 for school children of rural villages and these differences in mean OHI-S were statistically significant ( P < 0.005. In the 15-year-old age group, urban school children had a mean OHI-S score of 1.00 compared to 1.37 for rural towns and 1.43 for rural villages. The variance in the mean OHI-S scores were statistically significant ( P < 0.005. The overall level of cleanliness in the school children surveyed was good. Children of urban schools had the lowest scores followed by school children from rural towns and then rural villages. When the mean OHI-S scores were compared with the DMFT scores, there was an inverse relationship between oral cleanliness and dental caries. Frequency of sugar consumption and the availability and affordability of fluoridated toothpaste may be important factors in the development of dental caries than oral cleanliness.

  19. Use of social media is associated with short sleep duration in a dose-response manner in students aged 11 to 20 years.

    Science.gov (United States)

    Sampasa-Kanyinga, Hugues; Hamilton, Hayley A; Chaput, Jean-Philippe

    2018-04-01

    This study examined the association between social media and sleep duration among Canadian students aged 11-20. Data from 5242 students were obtained from the 2015 Ontario Student Drug Use and Health Survey, a province-wide, school-based survey that has been conducted every two years since 1977. We measured the respondents' sleep duration against the recommended ranges of 9-11 h per night at 11-13 years of age, 8-10 h at 14-17 and 7-9 h per night for those aged 18 years or more. Overall, 36.4% of students met or exceeded the recommended sleep duration and 63.6% slept less than recommended, with 73.4% of students reporting that they used social media for at least one hour per day. After adjusting for various covariates, the use of social media was associated with greater odds of short sleep duration in a dose-response manner (p for linear trend fashion among Canadian students aged 11-20. ©2018 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  20. Copy number variants in attention-deficit hyperactive disorder: identification of the 15q13 deletion and its functional role.

    Science.gov (United States)

    Valbonesi, Stefano; Magri, Chiara; Traversa, Michele; Faraone, Stephen V; Cattaneo, Annamaria; Milanesi, Elena; Valenti, Vera; Gennarelli, Massimo; Scassellati, Catia

    2015-04-01

    Evidence has supported a role for rare copy number variants in the etiology of attention-deficit hyperactivity disorder (ADHD), in particular, the region 15q13, which is also a hot spot for several neuropsychiatric disorders. This region spans several genes, but their role and the biological implications remain unclear. We carried out, for the first time, an analysis of the 15q13 region in an Italian cohort of 117 ADHD patients and 77 controls using the MLPA method, confirmed by a genome single-nucleotide polymorphism array. In addition, we probed for downstream effects of the 15q13 deletions on gene expression by carrying out a transcriptomic analysis in blood. We found 15q13 deletions in two ADHD patients and identified 129 genes as significantly dysregulated in the blood of the two ADHD patients carrying 15q13 deletions compared with ADHD patients without 15q13 deletions. As expected, genes in the deleted region (KLF13, MTMR10) were downregulated in the two patients with deletions. Moreover, a pathway analysis identified apoptosis, oxidation reduction, and immune response as the mechanisms that were altered most significantly in the ADHD patients with 15q13 deletions. Interestingly, we showed that deletions in KLF13 and CHRNA7 influenced the expression of genes belonging to the same immune/inflammatory and oxidative stress signaling pathways. Our findings are consistent with the presence of 15q13 deletions in Italian ADHD patients. More interestingly, we show that pathways related to immune/inflammatory response and oxidative stress signaling are affected by the deletion of KFL13 and CHRNA7. Because the phenotypic effects of 15q13 are pleiotropic, our findings suggest that there are shared biologic pathways among multiple neuropsychiatric conditions.

  1. Prevalence of Dental Caries in 5 – 6 Years and 12 – 13 Years Age Group of School Children of Kathmandu Valley

    Directory of Open Access Journals (Sweden)

    B Subedi

    2011-12-01

    Full Text Available Introduction: Dental caries is one of the most common conditions affecting the general health of children. The present study was carried out among school children of Kathmandu valley to determine the prevalence of dental caries in two age groups. Methods: The study was conducted from December 2007 to May 2008. The age of the school children of the study was divided into two group: 5 - 6 years and 12 - 13 years. A stratifi ed cluster sampling with proportional allocation was used while grouping the subjects. The dental status examination was done with the help of trained dentists. Decayed, missed and fi lled teeth index and decayed, missed and fi lled surfaces index (dmft for primary dentition and DMFT for permanent dentition were used as the standard tools for the determination of prevalence. Results: A total of 638 students (325 of age group 12 - 13 years and 313 of age group 5 - 6 years from 30 different schools of the Kathmandu valley were included in the study. The caries status was found higher in the age group of 5 - 6 years than in the 12 - 13 years and it was found to be statistically signifi cant (p < 0.001. The dmfs and caries percentage of the age group 5 - 6 years and the DMFS and caries percent of the 12 - 13 years was found to be 3.79, 69 % and 1.6, 53.23 % respectively. The dmft/dmfs value was found to be signifi cant according to the districts in the 5 - 6 years age group whereas the DMFS was found statistically signifi cant among the sexes of the 12 - 13 years age group. Conclusions: The caries percentage was found to be above the recommended level of the World Health Organization. However, the DMFS and DMFT values were within the WHO level. Keywords: Children, dental caries, DMF index.

  2. Smoking Prevalance in Women Aged Over 15 in Mardin City Center

    Directory of Open Access Journals (Sweden)

    Gunay Saka

    2008-04-01

    Full Text Available AIM/BACKGROUND: The purpose of this study is to determine prevalence of smoking and factors associated with it, in women aged over 15 years in Mardin city center. METHODS: This was a cross sectional study. The study population were 21 890 women aged over 15 years living in the area of five primary health centers (PHC in city center of Mardin. Minimum sample size was calculated 759 by using Epi Info2000. Health school students interviewed with women face to face by using questionnaire in April –May 2005. We randomly selected 12 streets from each PCH. From each street first 25 woman were included to the study. Because of data failure, 29 women’s questionnaires excluded and totally 1471 women composed the main source of our study data. Data were recorded and analysed by computer. Percentage and khi square test were used for statistical analyses. RESULTS: Smoking prevalence rate and giving up smoking rates were 22,9% and 3.9% respectively. Smoking prevalence was the highest in 25-34 age group (31.8% and the lowest in 55 years and over age group (10% (p<0.01. In terms of education the highest prevalence of smoking was among university graduates (34.3% while the lowest prevalence was among non-educated group (16.0% (p<0.01. Smoking prevalence was 30.4% in divorced women, 24.4% in married and 22.4 in unmarried group (p<0.05. Prevalence of smoking in working women (40.2% was higher than in non working group (21.7% (p<0.01. CONCLUSION: Smoking prevalence was high in women in Mardin and it was significant public health concern. The risky groups were young, higher educated, divorced and working woman. Detailed research must plan in these groups. Smoking cessation programs should target the population subgroups of women at highest risk of smoking. [TAF Prev Med Bull 2008; 7(2.000: 141-146

  3. Smoking Prevalance in Women Aged Over 15 in Mardin City Center

    Directory of Open Access Journals (Sweden)

    Vasfiye Deger

    2008-04-01

    Full Text Available AIM/BACKGROUND: The purpose of this study is to determine prevalence of smoking and factors associated with it, in women aged over 15 years in Mardin city center. METHODS: This was a cross sectional study. The study population were 21 890 women aged over 15 years living in the area of five primary health centers (PHC in city center of Mardin. Minimum sample size was calculated 759 by using Epi Info2000. Health school students interviewed with women face to face by using questionnaire in April –May 2005. We randomly selected 12 streets from each PCH. From each street first 25 woman were included to the study. Because of data failure, 29 women’s questionnaires excluded and totally 1471 women composed the main source of our study data. Data were recorded and analysed by computer. Percentage and khi square test were used for statistical analyses. RESULTS: Smoking prevalence rate and giving up smoking rates were 22,9% and 3.9% respectively. Smoking prevalence was the highest in 25-34 age group (31.8% and the lowest in 55 years and over age group (10% (p<0.01. In terms of education the highest prevalence of smoking was among university graduates (34.3% while the lowest prevalence was among non-educated group (16.0% (p<0.01. Smoking prevalence was 30.4% in divorced women, 24.4% in married and 22.4 in unmarried group (p<0.05. Prevalence of smoking in working women (40.2% was higher than in non working group (21.7% (p<0.01. CONCLUSION: Smoking prevalence was high in women in Mardin and it was significant public health concern. The risky groups were young, higher educated, divorced and working woman. Detailed research must plan in these groups. Smoking cessation programs should target the population subgroups of women at highest risk of smoking. [TAF Prev Med Bull. 2008; 7(2: 141-146

  4. Cardiopulmonary Resuscitation Training in Schools: A Comparison of Trainee Satisfaction among Different Age Groups.

    Science.gov (United States)

    Hori, Shingo; Suzuki, Masaru; Yamazaki, Motoyasu; Aikawa, Naoki; Yamazaki, Hajime

    2016-09-25

    Cardiopulmonary resuscitation (CPR) has recently been added to the school curriculum worldwide and is currently taught to students between the ages of 10 and 16 years. The effect of the age of trainees on their satisfaction with CPR training has yet been elucidated. The aim of this study was to compare the satisfaction of trainees of different ages who participated in CPR training in schools in Japan. In total, 392 primary school students (10-11 years old), 1798 junior high school students (12-13 years old), and 4162 high schools students (15-16 years old) underwent the same 3-h course of CPR training, according to the guidelines of 2000 for Emergency Cardiovascular Care and CPR. The course was evaluated by a questionnaire completed by the participants. Primary school students responded most positively to all questions, including those reflecting enjoyment and the confidence of participants to apply CPR (Jonckheere-Terpstra test: P CPR training was strongly related to their age. Primary school students enjoyed CPR training more and were more confident in their ability to perform CPR than junior high and high school students were. Therefore, children aged 10-11 years may be the most appropriate candidates for the introduction of CPR training in schools.

  5. A Survey of Psychological, Motivational, Family and Perceptions of Physics Education Factors that Explain 15-Year-Old Students' Aspirations to Study Physics in Post-Compulsory English Schools

    Science.gov (United States)

    Mujtaba, Tamjid; Reiss, Michael J.

    2014-01-01

    This paper investigates the factors that influence 15-year-old students' intentions to study physics post-16, when it is no longer compulsory. The analysis is based on the year 10 (age, 15 years) responses of 5,034 students from 137 England schools as learners of physics during the academic year 2008-2009. Factor analyses uncovered a range of…

  6. Computed tomography and magnetic resonance imaging of mild head injury - is it appropriate to classify patients with glasgow coma scale score of 13 to 15 as 'mild injury'?

    International Nuclear Information System (INIS)

    Uchino, Y.; Saeki, N.; Yamaura, A.; Okimura, Y.; Tanaka, M.

    2001-01-01

    Objective. The purpose of this study is to examine the relation between Glasgow coma scale (GCS) score and findings on computed tomography (CT) and magnetic resonance (MR) imaging of patients with mild head injury presenting GCS Scores between 13 and 15. Methods. Data were collected from all consecutive patients with mild head injury who were referred to our hospital between July 1 and October 31, 1999. All patients were recommended to undergo CT and MR imaging examinations. Patients younger than 14 years of age were excluded. Results. Ninety patients were recruited into this study. CT scans were obtained in 88 patients and MR imaging were obtained in 65 patients. Of those 90 patients, 2 patients scored 13 points, 5 scored 14 points and 83 (92.2 %) 15 points. Patients with GCS score of 13 points demonstrated parenchymal lesions an both CT and MR imaging. Those with 14 points revealed absence of parenchymal abnormality an CT, but presence of parenchymal lesions an MR imaging. Patients in advanced age (chi square test, p < 0.0001), and those with amnesia (p = 0005, not significant), although scoring 15 points, revealed a tendency to abnormal intracranial lesions on CT scans. Conclusion. It is doubtful whether patients with GCS score 13 should be included in the mild head injury category, due to obvious brain damage on CT scans. MR imaging should be performed on patients with GCS score 14, since the parenchymal lesions are not clearly demonstrated an CT scans. Even if patients scored GCS 15, patients which amnesia or of advanced age should undergo CT scans at minimum, and MR imaging when available. (author)

  7. Two new organic reference materials for δ13C and δ15N measurements and a new value for the δ13C of NBS 22 oil

    Science.gov (United States)

    Qi, Haiping; Coplen, Tyler B.; Geilmann, Heike; Brand, Willi A.; Böhlke, J.K.

    2003-01-01

    Analytical grade L-glutamic acid is chemically stable and has a C/N mole ratio of 5, which is close to that of many of natural biological materials, such as blood and animal tissue. Two L-glutamic acid reference materials with substantially different 13C and 15N abundances have been prepared for use as organic reference materials for C and N isotopic measurements. USGS40 is analytical grade L-glutamic acid and has a δ13C value of −26.24‰ relative to VPDB and a δ15N value of −4.52‰ relative to N2 in air. USGS41 was prepared by dissolving analytical grade L-glutamic acid with L-glutamic acid enriched in 13C and 15N. USGS41 has a δ13C value of +37.76‰ and a δ15N value of +47.57‰. The δ13C and δ15N values of both materials were measured against the international reference materials NBS 19 calcium carbonate (δ13C = +1.95‰), L-SVEC lithium carbonate (δ13C = −46.48‰), IAEA-N-1 ammonium sulfate (δ15N = 0.43‰), and USGS32 potassium nitrate (δ15N = 180‰) by on-line combustion continuous-flow and off-line dual-inlet isotope-ratio mass spectrometry. Both USGS40 and USGS41 are isotopically homogeneous; reproducibility of δ13C is better than 0.13‰, and that of δ15N is better than 0.13‰ in 100-μg amounts. These two isotopic reference materials can be used for (i) calibrating local laboratory reference materials, and (ii) quantifying drift with time, mass-dependent fractionations, and isotope-ratio-scale contraction in the isotopic analysis of various biological materials. Isotopic results presented in this paper yield a δ13C value for NBS 22 oil of −29.91‰, in contrast to the commonly accepted value of −29.78‰ for which off-line blank corrections probably have not been quantified satisfactorily.

  8. Vital signs: births to teens aged 15-17 years--United States, 1991-2012.

    Science.gov (United States)

    Cox, Shanna; Pazol, Karen; Warner, Lee; Romero, Lisa; Spitz, Alison; Gavin, Lorrie; Barfield, Wanda

    2014-04-11

    Teens who give birth at age 15-17 years are at increased risk for adverse medical and social outcomes of teen pregnancy. To examine trends in the rate and proportion of births to teens aged 15-19 years that were to teens aged 15-17 years, CDC analyzed 1991-2012 National Vital Statistics System data. National Survey of Family Growth (NSFG) data from 2006-2010 were used to examine sexual experience, contraceptive use, and receipt of prevention opportunities among female teens aged 15-17 years. During 1991-2012, the rate of births per 1,000 teens declined from 17.9 to 5.4 for teens aged 15 years, 36.9 to 12.9 for those aged 16 years, and 60.6 to 23.7 for those aged 17 years. In 2012, the birth rate per 1,000 teens aged 15-17 years was higher for Hispanics (25.5), non-Hispanic blacks (21.9), and American Indians/Alaska Natives (17.0) compared with non-Hispanic whites (8.4) and Asians/Pacific Islanders (4.1). The rate also varied by state, ranging from 6.2 per 1,000 teens aged 15-17 years in New Hampshire to 29.0 in the District of Columbia. In 2012, there were 86,423 births to teens aged 15-17 years, accounting for 28% of all births to teens aged 15-19 years. This percentage declined from 36% in 1991 to 28% in 2012 (pteens aged 15-17 years received formal sex education on birth control or how to say no to sex, 24% had not spoken with parents about either topic; among sexually experienced female teens, 83% reported no formal sex education before first sex. Among currently sexually active female teens (those who had sex within 3 months of the survey) aged 15-17 years, 58% used clinical birth control services in the past 12 months, and 92% used contraception at last sex; however, only 1% used the most effective reversible contraceptive methods. Births to teens aged 15-17 years have declined but still account for approximately one quarter of births to teens aged 15-19 years. These data highlight opportunities to increase younger teens exposure to interventions that delay

  9. Synthesis of (+-)-(1,1'- sup 15 N sub 2 , 2'- sup 13 C)-trans-3'-methylnicotine

    Energy Technology Data Exchange (ETDEWEB)

    Sirimanne, S.R.; Maggio, V.L.; Patterson, D.G. Jr. (Department of Health and Human Services, Atlanta, GA (United States))

    1992-03-01

    The synthesis of ({+-})- (1,1'-{sup 15}N{sub 2}, 2'-{sup 13}C)-trans-3'-methylnicotine is reported. {sup 15}N-3-Bromopyridine obtained from bromination of pyridine was formylated with nBuLi/(carbonyl-{sup 13}C)-methyl formate. The resulting {sup 15}n-Pyridine-3-({sup 13}C-carbonyl)-carboxaldehyde was reacted with {sup 15}N-methylamine and then the resulting Schiff's base was condensed with succinic anhydride to give ({+-})- (1,1'-{sup 15}N{sub 2}, 5'-{sup 13}C)-trans-4'-carboxycotinine. Reduction with lithium aluminum hydride and mesylation followed by reduction with Zn/NaI gave ({+-})-(1,1'-{sup 15}N{sub 2}, 2'-{sup 13}C)-trans-3'-methylnicotine. (Author).

  10. CARD15 single nucleotide polymorphisms 8, 12 and 13 are not increased in ethnic Danes with sarcoidosis

    DEFF Research Database (Denmark)

    Milman, Nils; Nielsen, Ole Haagen; Hviid, Thomas Vauvert F

    2007-01-01

    and SNP13, respectively, were performed by capillary electrophoresis single-strand confirmation polymorphism in 53 patients with histologically verified sarcoidosis and in 103 healthy controls. RESULTS: The frequencies of CARD15 mutations in sarcoidosis patients were: SNP8, 4/106 chromosomes (3.8%); SNP12...... with Crohn's disease. OBJECTIVES: To evaluate whether ethnic Danes with sarcoidosis have an increased frequency of CARD15 mutations compared to healthy control subjects. METHODS: Genotyping for CARD15 mutations R702W, G908R, and L1007fsinsC, also designated single nucleotide polymorphism (SNP) SNP8, SNP12......, 2/106 chromosomes (1.9%); SNP13, 2/106 chromosomes (1.9%); SNP8+SNP12+SNP13, 8/106 chromosomes (7.6%). All 8 patients were heterozygous. The frequencies in controls were: SNP8, 9/206 chromosomes (4.4%); SNP12, 2/206 chromosomes (1.0%); SNP13, 4/206 chromosomes (1.9%); SNP8+SNP12+SNP13, 15...

  11. Producing the Young Biocitizen: Secondary School Students' Negotiation of Learning in Physical Education

    Science.gov (United States)

    Petherick, LeAnne

    2013-01-01

    Given that the health of the nation is often interpreted in and through the health of the nation's youth, the threat of the "childhood obesity epidemic" garners much attention and it is hardly surprising that physical education has been recruited in the "war on [childhood] obesity". This paper explores how students aged 13-15

  12. 11p15 duplication and 13q34 deletion with Beckwith-Wiedemann syndrome and factor VII deficiency.

    Science.gov (United States)

    Jurkiewicz, Dorota; Kugaudo, Monika; Tańska, Anna; Wawrzkiewicz-Witkowska, Angelika; Tomaszewska, Agnieszka; Kucharczyk, Marzena; Cieślikowska, Agata; Ciara, Elżbieta; Krajewska-Walasek, Małgorzata

    2015-06-01

    Here we report a patient with 11p15.4p15.5 duplication and 13q34 deletion presenting with Beckwith-Wiedemann syndrome (BWS) and moderate deficiency of factor VII (FVII). The duplication was initially diagnosed on methylation-sensitive multiplex ligation-dependent probe amplification. Array comparative genome hybridization confirmed its presence and indicated a 13q34 distal deletion. The patient's clinical symptoms, including developmental delay and facial dysmorphism, were typical of BWS with paternal 11p15 trisomy. Partial 13q monosomy in this patient is associated with moderate deficiency of FVII and may also overlap with a few symptoms of paternal 11p15 trisomy such as developmental delay and some facial features. To our knowledge this is the first report of 11p15.4p15.5 duplication associated with deletion of 13q34 and FVII deficiency. Moreover, this report emphasizes the importance of detailed clinical as well as molecular examinations in patients with BWS features and developmental delay. © 2015 Japan Pediatric Society.

  13. Determinants of Tobacco Use among Students Aged 13-15 Years in Nepal and Sri Lanka: Results from the Global Youth Tobacco Survey, 2007

    Science.gov (United States)

    Kabir, M. A.; Goh, Kim-Leng

    2014-01-01

    Objectives: This study aimed to investigate tobacco use behaviours and their correlates among secondary school students in Nepal and Sri Lanka together with cross-country comparisons. Design: Cross-sectional survey. Methods and Settings: The data were obtained from the Global Youth Tobacco Survey (GYTS), 2007. Current tobacco use was considered as…

  14. Evaluation of some physical fitness characteristics in 11-13 years old

    Directory of Open Access Journals (Sweden)

    Ileana Monica Popovici

    2017-01-01

    Full Text Available Abstract Many studies indicate that a physical fitness characteristic is an important marker for healthy body and healthy mind. The major purpose of this study is to explore the levels of physical fitness of the students between 11 and 13 years of age. The participants of this study are 251 volunteer students including 95 boys and 156 girls between the ages 11 and 13 who participated at physical education lessons two times a week. The students were assessed for six anthropometric characteristics and five physical tests. Mean, standard deviation, and multiple comparisons were used for statistical analyses to find out differences between sexes with ANOVA, and Bonferoni Tests for differences between ages. Anthropometric measurements were reported as body mass index, height, weight, arm span, waist and hip and physical fitness traits such as agility, balance and strength. The findings suggest some differences between female and male students and between ages; male participants obtained higher results as means compared to female participants. Keywords: anthropometrics, agility, balances, strength, students

  15. Drug use in college students: a 13-year trend

    Directory of Open Access Journals (Sweden)

    Gabriela Arantes Wagner

    2012-06-01

    Full Text Available OBJECTIVE: To analyze drug use trends among college students in 1996, 2001 and 2009. METHODS: A cross-sectional epidemiological study with a multistage stratified cluster sample with 9,974 college students was conducted in the city of São Paulo, southeastern Brazil. An anonymous self-administered questionnaire was used to collect information on drug use assessed in lifetime, the preceding 12 months and the preceding 30 days. The Bonferroni correction was used for multiple comparisons of drug use rates between surveys. RESULTS: There were changes in the lifetime use of tobacco and some other drugs (hallucinogens [6.1% to 8.8%], amphetamines [4.6% to 8.7%], and tranquilizers [5.7% to 8.2%] from 1996 to 2009. Differences in the use of other drugs over the 12 months preceding the survey were also seen: reduced use of inhalants [9.0% to 4.8%] and increased use of amphetamines [2.4% to 4.8%]. There was a reduction in alcohol [72.9% to 62.1%], tobacco [21.3% to 17.2%] and marijuana [15.0% to 11.5%] use and an increase in amphetamine use [1.9% to 3.3%] in the preceeding 30 days. CONCLUSIONS: Over the 13-year study period, there was an increase in lifetime use of tobacco, hallucinogens, amphetamines, and tranquilizers. There was an increase in amphetamine use and a reduction in alcohol use during the preceding 12 months. There was an increase in amphetamine use during the preceding 30 days.

  16. Interleukin-13-induced MUC5AC is regulated by 15-lipoxygenase 1 pathway in human bronchial epithelial cells.

    Science.gov (United States)

    Zhao, Jinming; Maskrey, Ben; Balzar, Silvana; Chibana, Kazuyuki; Mustovich, Anthony; Hu, Haizhen; Trudeau, John B; O'Donnell, Valerie; Wenzel, Sally E

    2009-05-01

    15-Lipoxygenase-1 (15LO1) and MUC5AC are highly expressed in asthmatic epithelial cells. IL-13 is known to induce 15LO1 and MUC5AC in human airway epithelial cells in vitro. Whether 15LO1 and/or its product 15-HETE modulate MUC5AC expression is unknown. To determine the expression of 15LO1 in freshly harvested epithelial cells from subjects with asthma and normal control subjects and to determine whether IL-13-induced 15LO1 expression and activation regulate MUC5AC expression in human bronchial epithelial cells in vitro. Human airway epithelial cells from subjects with asthma and normal subjects were evaluated ex vivo for 15LO1 and MUC5AC expression. The impact of 15LO1 on MUC5AC expression in vitro was analyzed by inhibiting 15LO1 through pharmacologic (PD146176) and siRNA approaches in human bronchial epithelial cells cultured under air-liquid interface. We analyzed 15 hydroxyeicosatetraenoic acid (15-HETE) by liquid chromatography/UV/mass spectrometry. MUC5AC and 15LO1 were analyzed by real-time RT-PCR, immunofluoresence, and Western blot. Epithelial 15LO1 expression increased with asthma severity (P < 0.0001). 15LO1 significantly correlated with MUC5AC ex vivo and in vitro. IL-13 increased 15LO1 expression and stimulated formation of two molecular species of 15-HETE esterified to phosphotidylethanolamine (15-HETE-PE). Inhibition of 15LO1 suppressed 15-HETE-PE and decreased MUC5AC expression in the presence of IL-13 stimulation. The addition of exogenous 15-HETE partially restored MUC5AC expression. Epithelial 15LO1 expression increases with increasing asthma severity. IL-13 induction of 15-HETE-PE enhances MUC5AC expression in human airway epithelial cells. High levels of 15LO1 activity could contribute to the increases of MUC5AC observed in asthma.

  17. Large old trees influence patterns of delta13C and delta15N in forests.

    Science.gov (United States)

    Weber, Pascale; Bol, Roland; Dixon, Liz; Bardgett, Richard D

    2008-06-01

    Large old trees are the dominant primary producers of native pine forest, but their influence on spatial patterns of soil properties and potential feedback to tree regeneration in their neighbourhood is poorly understood. We measured stable isotopes of carbon (delta(13)C) and nitrogen (delta(15)N) in soil and litter taken from three zones of influence (inner, middle and outer zone) around the trunk of freestanding old Scots pine (Pinus sylvestris L.) trees, to determine the trees' influence on below-ground properties. We also measured delta(15)N and delta(13)C in wood cores extracted from the old trees and from regenerating trees growing within their three zones of influence. We found a significant and positive gradient in soil delta(15)N from the inner zone, nearest to the tree centre, to the outer zone beyond the tree crown. This was probably caused by the higher input of (15)N-depleted litter below the tree crown. In contrast, the soil delta(13)C did not change along the gradient of tree influence. Distance-related trends, although weak, were visible in the wood delta(15)N and delta(13)C of regenerating trees. Moreover, the wood delta(15)N of small trees showed a weak negative relationship with soil N content in the relevant zone of influence. Our results indicate that large old trees control below-ground conditions in their immediate surroundings, and that stable isotopes might act as markers for the spatial and temporal extent of these below-ground effects. John Wiley & Sons, Ltd

  18. Intergenerational Programs May Be Especially Engaging for Aged Care Residents With Cognitive Impairment: Findings From the Avondale Intergenerational Design Challenge.

    Science.gov (United States)

    Baker, Jess Rose; Webster, Lindl; Lynn, Nigel; Rogers, Julie; Belcher, Jessica

    2017-06-01

    Intergenerational programs are an authentic way to engage elders in meaningful activity and report benefits to both elders and youth. The Avondale Intergenerational Design Challenge (AVID) randomly assigned small teams of technology students aged 13 to 15 years (total N = 59) to 1 of 24 aged care residents with a range of cognitive impairment. Students met with the resident 4 times over 15 weeks and ultimately crafted a personalized item for them. Students showed no change in self-reported attitudes to elders, empathy, or self-esteem post-AVID or at 3-month follow-up, compared to a 3-month within-subject control period pre-AVID. Compared to usual lifestyle activities, residents showed significant improvements in self-reported positive affect and negative affect after student visits and were observed to be significantly more engaged during visits, especially residents with greater cognitive impairment. The personal and guided nature of intergenerational programs may be especially effective in engaging elders with cognitive impairment in meaningful activity.

  19. Prevalence of waterpipe tobacco smoking among population aged 15 years or older, Vietnam, 2010.

    Science.gov (United States)

    Xuan, Le Thi Thanh; Van Minh, Hoang; Giang, Kim Bao; Nga, Pham Thi Quynh; Hai, Phan Thi; Minh, Nguyen Thac; Hsia, Jason

    2013-04-18

    The prevalence of waterpipe tobacco smoking is increasing globally and is associated with adverse outcomes requiring tobacco control interventions. We estimated the prevalence of waterpipe tobacco use among adult populations in Vietnam in 2010 and examined its association with sociodemographic factors. We used data from the Global Adult Tobacco Survey (GATS) conducted in Vietnam in 2010. GATS surveyed a national representative sample of adults aged 15 years or older from 11,142 households by using a 2-phase sampling design analogous to a 3-stage stratified cluster sampling. Descriptive statistical analyses and multivariate logistic regression modeling were conducted. A total of 6.4% of Vietnamese aged 15 years or older (representing about 4.1 million adult waterpipe smokers) reported current waterpipe tobacco smoking. The prevalence of waterpipe tobacco smoking was significantly higher among men than women (13% vs 0.1%). Area of residence (rural or urban), age group, asset-based wealth quintile, and geographic region of residence were significantly associated with waterpipe tobacco smoking among men. The significant correlates of current waterpipe tobacco smoking among men were lower education levels, being middle-aged (45-54 years), lower asset-based wealth levels, living in rural areas, not living in the South East and the Mekong River Delta geographic regions, and the belief that smoking does not causes diseases. Rural dwellers who are poor should be targeted in tobacco control programs. Further studies are needed that examine perceptions of the adverse health effects and the cultural factors of waterpipe tobacco smoking.

  20. Fertility of men and women aged 15-44 years in the United States: National Survey of Family Growth, 2006-2010.

    Science.gov (United States)

    Martinez, Gladys; Daniels, Kimberly; Chandra, Anjani

    2012-04-12

    This report presents national estimates of the fertility of men and women aged 15-44 years in the United States in 2006-2010 based on the National Survey of Family Growth (NSFG). Data are compared with similar measures for 2002. Descriptive tables of numbers, percentages, and means are presented and discussed. Data were collected through in-person interviews of a nationally representative sample of the household population aged 15-44 years in the United States between July 2006 and June 2010. The 2006-2010 NSFG sample is comprised of 22,682 respondents including 10,403 men and 12,279 women. The overall response rate for the 2006-2010 NSFG was 77%, 75% for men and 78% for women. Many of the fertility measures among men and women aged 15-44 based on the 2006-2010 NSFG were generally similar to those reported based on the 2002 NSFG. The mean age at first child's birth for women was 23 and the mean age at first child's birth for men was 25. One-half of first births to women were in their 20s and two-thirds of first births were fathered by men who were in their 20s. On average, women aged 15-44 have 1.3 children as of the time of the interview. By age 40, 85% of women had had a birth, and 76% of men had fathered a child. In 2006-2010, 22% of first births to women occurred within cohabiting unions, up from 12% in 2002. These measures differed by Hispanic origin and race and other demographic characteristics.

  1. Temperament and body weight from ages 4 to 15 years.

    Science.gov (United States)

    Sutin, A R; Kerr, J A; Terracciano, A

    2017-07-01

    In adulthood, conscientiousness and neuroticism are correlates of body weight and weight gain. The present research examines whether the childhood antecedents of these traits, persistence and negative reactivity, respectively, are associated with weight gain across childhood. We likewise examine sociability as a predictor of childhood weight gain and whether these three traits are associated with weight concerns and weight-management strategies in adolescence. Participants (N=4153) were drawn from the Longitudinal Study of Australian Children, an ongoing, population-based study of child and family health and well-being. At the baseline assessment, caregivers reported on their child's temperament. At every assessment from ages 4-5 to 14-15 years, study children were weighed and measured by trained staff; there were up to six biennial assessments of body mass index and waist circumference. At ages 14-15 years, study children (n=2975) also self-reported on their weight concerns and weight-management strategies. Study children rated lower in persistence or higher in negative reactivity in early childhood gained more weight between the ages of 4 and 15 years. Sociability was associated with weight gain among girls but not among boys. Lower persistence and higher negative reactivity at ages 4-5 years were also associated with greater weight concerns, restrained eating and use of unhealthy weight-management strategies at ages 14-15 years. Childhood traits related to conscientiousness and neuroticism are associated with objective weight gain across childhood and with concerns and strategies to manage weight in adolescence. These results are consistent with a lifespan perspective that indicates that trait psychological functioning contributes to health-related markers from childhood through old age.

  2. [Acceptance of a total smoking ban in schools: students' attitudes].

    Science.gov (United States)

    Morgenstern, M; Wiborg, G; Hanewinkel, R

    2008-06-01

    The purpose of this study was to measure students' attitudes towards a total smoking ban in schools and towards impositions in cases of violation. Cross-sectional survey of 1 738 students of 12 public schools in Schleswig-Holstein (grades 7-13, age 11-20 years). Data were collected by means of written questionnaires administered during class time. The following variables were assessed: attitude towards smoking ban, attitude towards impositions, age, sex, citizenship, perceived school climate, current smoking, lifetime smoking; for smokers, and additionally, the "Heaviness of Smoking Index". 76.5% of all students agreed with a total smoking ban, 66.4% agreed with the punishment of violations. Higher acceptance rates were found among girls, young students (11-15 years of age), for never-smokers, and for students who feel comfortable at school. Acceptance of the smoking ban is closely related to current smoking status: 93% of the non-smoking students, but only 14% of the daily smoking students agreed with the regulations. Refusal of the ban increased with increasing physical dependence. The intensification of the smoking ban in public schools meets approval by the majority of students. Smoking students should be more strongly involved in the implementation process, e.g., by supplemental cessation programmes.

  3. Familial and sporadic 15q13.3 microdeletions in idiopathic generalized epilepsy: precedent for disorders with complex inheritance

    DEFF Research Database (Denmark)

    Dibbens, Leanne M; Mullen, Saul; Helbig, Ingo

    2009-01-01

    Microdeletion at chromosomal position 15q13.3 has been described in intellectual disability, autism spectrum disorders, schizophrenia and recently in idiopathic generalized epilepsy (IGE). Using independent IGE cohorts, we first aimed to confirm the association of 15q13.3 deletions and IGE. We...... then set out to determine the relative occurrence of sporadic and familial cases and to examine the likelihood of having seizures for individuals with the microdeletion in familial cases. The 15q13.3 microdeletion was identified in 7 of 539 (1.3%) unrelated cases of IGE using quantitative PCR or SNP arrays...... and confirmed by array comparative genomic hybridization analysis using probes specific to the 15q13.3 region. The inheritance of this lesion was tracked using family studies. Of the seven microdeletions identified in probands, three were de novo, two were transmitted from an unaffected parent and in two cases...

  4. Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice.

    Science.gov (United States)

    Zhang, Wenliang; Zhong, Wei; Sun, Qian; Sun, Xinguo; Zhou, Zhanxiang

    2017-08-21

    Chronic alcohol feeding causes lipid accumulation and apoptosis in the liver. This study investigated the role of bioactive lipid metabolites in alcohol-induced liver damage and tested the potential of targeting arachidonate 15-lipoxygenase (ALOX15) in treating alcoholic liver disease (ALD). Results showed that chronic alcohol exposure induced hepatocyte apoptosis in association with increased hepatic 13-HODE. Exposure of 13-HODE to Hepa-1c1c7 cells induced oxidative stress, ER stress and apoptosis. 13-HODE also perturbed proteins related to lipid metabolism. HODE-generating ALOX15 was up-regulated by chronic alcohol exposure. Linoleic acid, but not ethanol or acetaldehyde, induced ALOX15 expression in Hepa-1c1c7 cells. ALOX15 knockout prevented alcohol-induced liver damage via attenuation of oxidative stress, ER stress, lipid metabolic disorder, and cell death signaling. ALOX15 inhibitor (PD146176) treatment also significantly alleviated alcohol-induced oxidative stress, lipid accumulation and liver damage. These results demonstrated that activation of ALOX15/13-HODE circuit critically mediates the pathogenesis of ALD. This study suggests that ALOX15 is a potential molecular target for treatment of ALD.

  5. Prevalence of Mental Disorders in 6–16-Year-Old Students in Sichuan Province, China

    Directory of Open Access Journals (Sweden)

    Yuan Qu

    2015-05-01

    Full Text Available To investigate the point prevalence of mental disorders in school students, multistage cluster stratified random sampling and two-phase survey methods were used to identify 40 primary and middle schools. The students were screened using the Chinese version of the Child Behavior Checklist and diagnosed using the Mini International Neuropsychiatric Interview. The prevalence of behavioral problems was 19.13%. The prevalence of behavioral problems significantly differed by sex, age, city of residence, and caretaker. The six-month prevalence of any mental disorder was 15.24% (95% CI: 15.49%–16.97%. Psychiatric disorders were more prevalent in boys (17.33% relative to girls (13.11%; p < 0.01. The prevalence of mental disorders significantly differed by community and caretaker, and 36.46% of students exhibited comorbidity. Results demonstrated important mental health issues, with a high incidence of comorbidities, in this population. Students’ mental health requires increased attention, particularly in poverty-stricken areas and left-behind children and adolescents.

  6. AJESMS_ Vol 8 2010 August 15 2011

    African Journals Online (AJOL)

    Prof. Mereku

    2010-08-15

    Aug 15, 2010 ... perception of, and attitude to, HIV/AIDS prevention among ... Counselling, Cross River University of Technology, Calabar. 13 ... population of 12,846 senior secondary school students in the eighteen (18) local government.

  7. Suplementação energética pré-acasalamento aos 13/15 meses de idade para novilhas de corte: desenvolvimento e desempenho reprodutivo Pre-mating energetic supplementation at 13/15 months of age for beef heifers: development and reproductive performance

    Directory of Open Access Journals (Sweden)

    Alcides Pilau

    2009-12-01

    dias pré-acasalamento proporciona maior taxa de prenhez em novilhas de corte aos 13/15 meses de idade.The effect was assessed of pre-mating supplementary feeding on the reproductive performance of 13-15 month old beef heifers. Eighty-nine heifers were used with a mean age of 12 months and mean body weight (BW of 242 kg from three herds Aberdeen Angus heifers from the Santa Cecilia and Capitao Rodrigo ranches and crossbred Aberdeen Angus heifers in a feeding system of only grazing pasture or supplemented heifers on pasture with milled corn grain. The supplement was offered daily at the proportion of 0.7% of the BW for 29 days on Oats (Avena strigosa Schreb and annual Ryegrass (Lolium multiflorum Lam cultivated pastures and 19 days on natural pasture. The grazing was continuous with variable stocking rate. The variables analyzed were: body weight, body condition, average daily live weight gain, body condition gain, percentage of pubescent heifers, pregnancy rate and conception order. There was no feeding systems ×herd interaction. During the pre-mating, the supplemented heifers had greater ADG, 0.800 kg, compared to those without supplementation, 0.658 kg. During the mating period, the heifers lost weight, mean of -0.104 kg/day. The variables body weight and body condition did not differ at the beginning of the mating period mean of 277 kg and 3.6 points, respectively. The supplemented heifers showed higher percentage of pubescent heifers (78% and higher pregnancy rate (47%. There was herd ×period interaction for body weight. The body weight variation was quadratic for the three herds. Crossbred heifers always had greater body weight compared to the Santa Cecília Angus heifers. Capitão Rodrigo Angus heifers had higher higher percentage of pubescent heifers (80% and PR (48%. Energy supplementation during 48 days pre-mating promoted higher pregnancy rate in 13 to 15 month old beef heifers.

  8. Fate of [15N]glycine in peat as determined by 13C and 15N CP-MAS NMR spectroscopy

    International Nuclear Information System (INIS)

    Benzing-Purdie, L.M.; Cheshire, M.V.; Williams, B.L.; Sparling, G.P.; Ratcliffe, C.I.; Ripmeester, J.A.

    1986-01-01

    Peat samples, nonsterile, sterilized by γ irradiation or autoclaving, were incubated with [ 15 N]glycine for a period of 6 months. The 13 C NMR data showed the established trend of increased humification with decreasing particle size and that autoclaving had significantly disturbed the humification-particle size distribution. The 15 N CP-MAS NMR spectra showed the presence of [ 15 N]glycine in all fractions after incubation. 15 NH 4 + , a result of either biological or chemical deamination, was one of the main products in the nonsterile peat series. The 15 N spectra also showed resonances corresponding to amine, secondary amide, and pyrrole-type nitrogen and the presence of glycine derivatives and melanoidins. The results presented give the first spectroscopic evidence of the possible involvement of the Maillard reaction in the humification process

  9. Knowledge and Attitude Towards Tobacco Smoking among 13-15 Year-Old School Children in Viet Nam - Findings from GYTS 2014.

    Science.gov (United States)

    Huong, Nguyen Thanh; Kien, Nguyen Trung; Giang, Kim Bao; Minh, Hoang Van; Hai, Phan Thi; Huyen, Doan Thu; Khue, Luong Ngoc; Linh, Nguyen Thuy; Lam, Nguyen Tuan; Nga, Pham Thi Quynh

    2016-01-01

    Studies have shown that smoking is a learnt behavior, often initiated during adolescence. This paper aims to describe tobacco-related knowledge, attitude and associations among school adolescents aged 13-15 with exposure to anti-smoking information. Using data from the Global Youth Tobacco Survey (GYTS) in Viet Nam, 2014, knowledge was measured through 4 questions about tobacco use, and attitude was assessed through 3 questions on personal, social and environmental aspects. Students giving most anti-tobacco responses to all questions were considered as having correct knowledge or appropriate attitude or both. Access to anti-smoking information was determined by exposure to any media messages on tobacco control during the past 30 days and teaching in school about the danger of tobacco use during the past 12 months. A substantial percentage of students thought that being near others who smoke might be harmful to them and smoking is harmful to health (89.4% and 89.6% respectively). However, only 46.4% reported that it is definitely difficult to quit smoking and 66.9% thought that smoking for only 1 or 2 years, once stopped, is harmful to health. Slightly more than half of the respondents reported appropriate attitude that young smokers have fewer friends than others and smoking makes them less attractive and less comfortable at social events. Noticing anti-smoking messages in the media together with having lessons in school about the dangers of tobacco substantially increased the likelihood of having correct knowledge, appropriate attitude and both. Despite relatively high awareness about smoking harms, effective educational communication is still highly needed to improve the level of comprehensive knowledge and an appropriate attitude regarding tobacco use.

  10. Further evidence of accelerated aging in bipolar disorder: Focus on GDF-15

    Directory of Open Access Journals (Sweden)

    Yang Fang

    2018-03-01

    Full Text Available Bipolar disorder (BD is a mood disorder associated with cardiovascular and metabolic diseases and premature aging. Growth differentiation factor 15 (GDF-15 has emerged as a biomarker for cardiovascular risk and aging. Our aim was to compare plasma levels of GDF-15 between BD patients and controls, and to evaluate whether they were associated with clinical parameters.

  11. [Drinking and drug abuse among gymnasium students in Szczecin].

    Science.gov (United States)

    Musiał, Barbara; Czaja-Bulsa, Grazyna; Szechter-Grycewicz, Aneta; Brodzińska, Beata; Marasz, Agata

    2012-01-01

    The aim of this work was to determine the extent and causes of drinking and drug abuse by the youth. A questionnaire was administered to 918 students aged 13-16 years from five gymnasia in Stettin. The results were analyzed statistically. In the group of 918 students, 76% were alcohol drinkers and 15% abused psychoactive substances. Among causes of drinking and drug abuse were family and personal problems, impressing colleagues, fashion, advertisements, and stress. Alcohol drinking and drug abuse are not only a response to personal and family problems, but also the result of role models accepted by gymnasium students. Lack of control and support within the family are factors liberating alcohol consumption and drug abuse among the youth.

  12. ‘Lightning talks’ from the CERN openlab summer students | 15 and 18 August 2016

    CERN Multimedia

    Andrew Purcell

    2016-01-01

    On Monday 15 and Thursday 18 August, this year’s CERN openlab summer students will present their work in dedicated public ‘lighting talk’ sessions.    In 5-minute presentations, each CERN openlab summer student will introduce their project, explain the technical challenges and describe the results of what they have been working on for the past few weeks. This year, the CERN openlab Summer Student Programme is hosting 39 students representing 21 different nationalities for nine weeks.  The lightning talks will take place in the IT Amphitheatre (31/3-004) from 15:00 to 18:00 on Monday 15 August and Thursday 18 August. For more information, please visit the CERN openlab website and the Indico pages 15/08/2016 and 18/08/2016.

  13. Isothermal aging effects on PMR-15 resin

    Science.gov (United States)

    Bowles, Kenneth J.; Jayne, Douglas; Leonhardt, Todd A.

    1993-01-01

    Specimens of PMR-15 polyimide neat resin were aged in air at temperatures of 288, 316, and 343 C. Weight losses and dimensional changes were monitored during the course of the exposure time. Physical changes were also observed by optical and electron microscopy. It was found that polyimide polymer degradation occurred within a thin surface layer that developed and grew during thermal aging. The cores of the polymer specimens were protected from oxidative degradation, and they were relatively unchanged by the thermal treatment. Surface cracking was observed at 343 C and was probably due to an interaction between voids and stresses that developed in the surface layer.

  14. Comparison of onset age and pattern of male adolescent smoking in two different socioeconomic districts of Tehran, Iran

    OpenAIRE

    Fatemeh Rezaei; Saharnaz Nedjat; Banafsheh Golestan; Reza Majdzadeh

    2011-01-01

    Objectives: One of the main strategies to prevent smoking is delaying onset of smoking in adolescents. Thus, identifying the age of smoking and smoking pattern in adolescents gives important knowledge for planning the intervention programs on smoking. Methods: Students aged 13-15 years old living in the Northern and the Southern Tehran were selected through two separate snowball samplings. In each area six smokers were considered as the seeds and were asked to introduce a smoker friend. The s...

  15. Interleukin-13–induced MUC5AC Is Regulated by 15-Lipoxygenase 1 Pathway in Human Bronchial Epithelial Cells

    Science.gov (United States)

    Zhao, Jinming; Maskrey, Ben; Balzar, Silvana; Chibana, Kazuyuki; Mustovich, Anthony; Hu, Haizhen; Trudeau, John B.; O'Donnell, Valerie; Wenzel, Sally E.

    2009-01-01

    Rationale: 15-Lipoxygenase-1 (15LO1) and MUC5AC are highly expressed in asthmatic epithelial cells. IL-13 is known to induce 15LO1 and MUC5AC in human airway epithelial cells in vitro. Whether 15LO1 and/or its product 15-HETE modulate MUC5AC expression is unknown. Objectives: To determine the expression of 15LO1 in freshly harvested epithelial cells from subjects with asthma and normal control subjects and to determine whether IL-13–induced 15LO1 expression and activation regulate MUC5AC expression in human bronchial epithelial cells in vitro. Methods: Human airway epithelial cells from subjects with asthma and normal subjects were evaluated ex vivo for 15LO1 and MUC5AC expression. The impact of 15LO1 on MUC5AC expression in vitro was analyzed by inhibiting 15LO1 through pharmacologic (PD146176) and siRNA approaches in human bronchial epithelial cells cultured under air–liquid interface. We analyzed 15 hydroxyeicosatetraenoic acid (15-HETE) by liquid chromatography/UV/mass spectrometry. MUC5AC and 15LO1 were analyzed by real-time RT-PCR, immunofluoresence, and Western blot. Measurements and Main Results: Epithelial 15LO1 expression increased with asthma severity (P < 0.0001). 15LO1 significantly correlated with MUC5AC ex vivo and in vitro. IL-13 increased 15LO1 expression and stimulated formation of two molecular species of 15-HETE esterified to phosphotidylethanolamine (15-HETE-PE). Inhibition of 15LO1 suppressed 15-HETE-PE and decreased MUC5AC expression in the presence of IL-13 stimulation. The addition of exogenous 15-HETE partially restored MUC5AC expression. Conclusions: Epithelial 15LO1 expression increases with increasing asthma severity. IL-13 induction of 15-HETE-PE enhances MUC5AC expression in human airway epithelial cells. High levels of 15LO1 activity could contribute to the increases of MUC5AC observed in asthma. PMID:19218191

  16. Age patterns of smoking initiation among Kuwait university male students.

    Science.gov (United States)

    Sugathan, T N; Moody, P M; Bustan, M A; Elgerges, N S

    1998-12-01

    The present study is a detailed evaluation of age at smoking initiation among university male students in Kuwait based on a random sample of 664 students selected from all students during 1993. The Acturial Life Table analysis revealed that almost one tenth of the students initiated cigarette smoking between ages 16 and 17 with the rate of initiation increasing rapidly thereafter and reaching 30% by age 20 and almost 50% by the time they celebrate their 24th birthday. The most important environmental risk factor positively associated for smoking initiation was observed to be the history of smoking among siblings with a relative risk of 1.4. Compared to students of medicine and engineering, the students of other faculties revealed a higher risk in smoking initiation with an RR = 1.77 for sciences and commerce and 1.61 for other faculties (arts, law, education and Islamic studies). The analysis revealed a rising generation trend in cigarette smoking. There is a need for reduction of this trend among young adults in Kuwait and throughout other countries in the region.

  17. Attitudes of early adolescent age students towards physical education

    Directory of Open Access Journals (Sweden)

    Lazarević Dušanka

    2015-01-01

    Full Text Available Studies have shown that a positive attitude towards physical education (PE is in connection with students' engagement in PE classes and with the development of an active lifestyle. The objective of this study was to examine attitudes of early adolescent age students towards physical education, as well as to examine whether such attitudes vary with regard to gender, grade they attend and students' engagement in sport and physical exercises in extracurricular activities. The research was conducted on the sample of 531 students from 6th to 8th grade. The instrument Student's Attitudes toward Physical Education - SATPE was used to measure student's attitude towards PE. A special questionnaire was used to collect data on gender, grade and engagement in sport and physical exercising outside school. The results have shown that students have positive attitudes of moderate intensity towards physical education. MANOVA has shown that male students have more positive attitudes than female students, as well as that positivity of attitudes declines with age. Likewise, it was shown that students with more positive attitudes towards PE are more often engaged in physical exercises outside school. The connection between the attitude towards PE and involvement in organized sport was not confirmed. The paper presents suggestions for further research of students' attitude towards PE and its connection with physical activity of students.

  18. Changes of stable isotopes carbon-13 and nitrogen-15 in different tissues of cattle

    International Nuclear Information System (INIS)

    Sun Fengmei; Yu Hongxia; Wu Wei; Yang Shuming

    2009-01-01

    Stable isotope analysis is a potential tool for tracing food origin. The stable carbon and nitrogen isotope composition in different tissues of two varieties of cattle under the same culture condition were investigated. δ 13 C and δ 15 N values of different defatted muscle and crude fat, cattle tail hair, blood, liver and feed were determined by isotope ratio mass spectrometry, and statistical analysis was carried out. The results showed that stable isotopes of carbon and nitrogen composition was not affected by cattle variety; the δ 13 C values between different defatted muscle, blood, liver and cattle hair were not significantly different, but δ 15 N value in the liver was much higher than other muscle and the δ 13 C values didn't show difference among all the crude fat samples. So these results indicated that isotope fractionation in the various tissue was discrepant. (authors)

  19. Professor Age and Gender Affect Student Perceptions and Grades

    Science.gov (United States)

    Joye, Shauna W.; Wilson, Janie H.

    2015-01-01

    Student evaluations provide rich information about teaching performance, but a number of factors beyond teacher effectiveness influence student evaluations. In this study we examined the effects of professor gender and perceived age on ratings of effectiveness and rapport as well as academic performance. We also asked students to rate professor…

  20. Hypertriglyceridemic Waist Phenotype in Adolescents Aged 15 to 18 Years

    Directory of Open Access Journals (Sweden)

    Caridad Hernández Gutiérrez

    2015-09-01

    Full Text Available Background: presence of the hypertriglyceridemic waist phenotype is a predictor of cardiometabolic deterioration, increased type 2 diabetes mellitus and coronary heart disease. Objective: to determine the hypertriglyceridemic waist phenotype in adolescents aged 15 to 18 years from the Area III of Cienfuegos. Method: a case series study was conducted in a universe of 198 adolescents aged 15 to 18 years who attended a consultation created for this study at the Octavio de la Concepción y de la Pedraja University Polyclinic in Cienfuegos municipality from March to December 2013. Each patient completed a questionnaire including the following variables: age, sex, personal medical history, family medical history, weight, height, body mass index, presence of acanthosis nigricans, triglycerides and perimeter. Results: frequency of the phenotype was determined in 15.1 % of the participants with a slight predominance of the 18 age group (16.3 % and female sex (8.6 %. Twenty-one point six percent of the adolescents with a family history of obesity and 21.7 % of those with first-degree diabetic relatives presented the phenotype, being hypertriglyceridemia the most significant condition. Conclusions: a relationship between a family history of diabetes mellitus, obesity, body mass index above the 90th percentile value and presence of the phenotype was established.

  1. Effect of body size and body mass on δ 13 C and δ 15 N in coastal fishes and cephalopods

    Science.gov (United States)

    Vinagre, C.; Máguas, C.; Cabral, H. N.; Costa, M. J.

    2011-11-01

    Carbon and nitrogen isotopes have been widely used in the investigation of trophic relations, energy pathways, trophic levels and migrations, under the assumption that δ 13C is independent of body size and that variation in δ 15N occurs exclusively due to ontogenetic changes in diet and not body size increase per se. However, several studies have shown that these assumptions are uncertain. Data from food-webs containing an important number of species lack theoretical support on these assumptions because very few species have been tested for δ 13C and δ 15N variation in captivity. However, if sampling comprises a wide range of body sizes from various species, the variation of δ 13C and δ 15N with body size can be investigated. While correlation between body size and δ 13C and δ 15N can be due to ontogenetic diet shifts, stability in such values throughout the size spectrum can be considered an indication that δ 13C and δ 15N in muscle tissues of such species is independent of body size within that size range, and thus the basic assumptions can be applied in the interpretation of such food webs. The present study investigated the variation in muscle δ 13C and δ 15N with body size and body mass of coastal fishes and cephalopods. It was concluded that muscle δ 13C and δ 15N did not vary with body size or mass for all bony fishes with only one exception, the dragonet Callionymus lyra. Muscle δ 13C and δ 15N also did not vary with body size or mass in cartilaginous fishes and cephalopods, meaning that body size/mass per se have no effect on δ 13C or δ 15N, for most species analysed and within the size ranges sampled. The assumption that δ 13C is independent of body size and that variation in δ 15N is not affected by body size increase per se was upheld for most organisms and can be applied to the coastal food web studied taking into account that C. lyra is an exception.

  2. Cognitive Functions in Elite and Sub-Elite Youth Soccer Players Aged 13 to 17 Years.

    Directory of Open Access Journals (Sweden)

    Barbara C H Huijgen

    Full Text Available Soccer players are required to anticipate and react continuously in a changing, relatively unpredictable situation in the field. Cognitive functions might be important to be successful in soccer. The current study investigated the relationship between cognitive functions and performance level in elite and sub-elite youth soccer players aged 13-17 years. A total of 47 elite youth soccer players (mean age 15.5 years, SD = 0.9 and 41 sub-elite youth soccer players (mean age 15.2 years, SD = 1.2 performed tasks for "higher-level" cognitive functions measuring working memory (i.e., Visual Memory Span, inhibitory control (i.e., Stop-Signal Task, cognitive flexibility (i.e., Trail Making Test, and metacognition (i.e., Delis-Kaplan Executive Function System Design Fluency Test. "Lower-level" cognitive processes, i.e., reaction time and visuo-perceptual abilities, were also measured with the previous tasks. ANOVA's showed that elite players outscored sub-elite players at the "higher-level" cognitive tasks only, especially on metacognition (p .05. In conclusion, elite youth soccer players have better inhibitory control, cognitive flexibility, and especially metacognition than their sub-elite counterparts. However, when training hours are taken into account, differences between elite and sub-elite youth soccer players remain apparent on inhibitory control and cognitive flexibility in contrast to metacognition. This highlights the need for longitudinal studies to further investigate the importance of "higher-level" cognitive functions for talent identification, talent development and performance in soccer.

  3. Cognitive Functions in Elite and Sub-Elite Youth Soccer Players Aged 13 to 17 Years

    Science.gov (United States)

    Huijgen, Barbara C. H.; Leemhuis, Sander; Kok, Niels M.; Verburgh, Lot; Oosterlaan, Jaap; Elferink-Gemser, Marije T.; Visscher, Chris

    2015-01-01

    Soccer players are required to anticipate and react continuously in a changing, relatively unpredictable situation in the field. Cognitive functions might be important to be successful in soccer. The current study investigated the relationship between cognitive functions and performance level in elite and sub-elite youth soccer players aged 13–17 years. A total of 47 elite youth soccer players (mean age 15.5 years, SD = 0.9) and 41 sub-elite youth soccer players (mean age 15.2 years, SD = 1.2) performed tasks for “higher-level” cognitive functions measuring working memory (i.e., Visual Memory Span), inhibitory control (i.e., Stop-Signal Task), cognitive flexibility (i.e., Trail Making Test), and metacognition (i.e., Delis-Kaplan Executive Function System Design Fluency Test). “Lower-level” cognitive processes, i.e., reaction time and visuo-perceptual abilities, were also measured with the previous tasks. ANOVA’s showed that elite players outscored sub-elite players at the “higher-level” cognitive tasks only, especially on metacognition (p .05). In conclusion, elite youth soccer players have better inhibitory control, cognitive flexibility, and especially metacognition than their sub-elite counterparts. However, when training hours are taken into account, differences between elite and sub-elite youth soccer players remain apparent on inhibitory control and cognitive flexibility in contrast to metacognition. This highlights the need for longitudinal studies to further investigate the importance of “higher-level” cognitive functions for talent identification, talent development and performance in soccer. PMID:26657073

  4. Genetic Polymorphisms of 15 STR Loci within Turkish Student Population Living in Sarajevo, Bosnia and Herzegovina

    OpenAIRE

    Dogan, Serkan; Kovačević, Lejla; Marjanović, Damir

    2013-01-01

    Allele frequencies of 15 STRs included in the PowerPlex 16 System (D3S1358, TH01, D21S11, D18S51, Penta E, D5S818, D13S317, D7S820, D16S539, CSF1PO, Penta D, VWA, D8S1179, TPOX and FGA) were calculated from the referent sample of 100 unrelated individuals of both sexes from Turkish student population living in Sarajevo, Bosnia and Herzegovina. Buccal swab, as a source of DNA, was collected from the volunteers from whom the informed consent form was obtained. DNA extraction was performed using...

  5. Applications of stable isotopes of 2H, 13C and 15N to clinical problems

    International Nuclear Information System (INIS)

    Klein, P.D.; Szczepanik, P.A.; Hachey, D.L.

    1974-01-01

    The function of the Argonne Program is to provide synthetic, analytical instrumental capability in a core facility for the clinical investigator who needs to use 2 H, 13 C, or 15 N labelled compounds for metabolic or clinical research on pregnant women, newborn infants, young children, or for mass screening. To carry out such application development, there were six stages which were recurrent steps in every application. Five fundamental strategies should be adopted to establish the use of stable isotopes in clinical work. The instrument required for measurements was a combined gas chromatograph-mass spectrometer, and its use was schematically illustrated. Some of the successful experiences with compounds labelled by stable isotopes, such as deuterium labelled chenodeoxycholic acid, and respective 13 C and 15 N-labelled glycine were described. Deutrium labelled bile acid enabled easy and safe determination of the size of the bile acid pool and the replacement rate, providing clearer diagnoses for cholestatic liver disease and gallstones. 13 C and 15 N labelled compounds were used in clinical studies, of children with genetic disorders of amino acid metabolism, i.e., non ketotic hyperflycinemia, B 12 -responsive methyl malonic acidemia, and Lesch-Nyhan syndrome. 15 N-labelled glycine was also studied in a child with Lesch-Nyhan syndrome. (Mukohata, S.)

  6. Postural reactions of girls and boys aged 12–15 years evaluated using the Romberg test

    Directory of Open Access Journals (Sweden)

    Jacek Wilczyński

    2016-07-01

    Full Text Available Introduction : The complex system controlling human posture includes a gaze stabilisation system, which comprises the control of direction and visual acuity during head and body movements, and a posture stabilisation system, keeping the body in balance at rest and in movement. Aim of the research: To analyse the postural reaction of SOX and SOY using the Romberg test with eyes open (EO and closed (CE in girls and boys aged 12–15 years. Material and methods : The study included 503 students of Primary School No. 13 and School No. 4 in Starachowice. Postural reactions were tested on a Cosmogamma platform by Emildue R50300. Postural reactions were analysed, and mean sway X (MSX and mean sway Y (MSY were calculated. Results: Analysis of variance showed significant differences of MSX only between girls and boys (p < 0.036. MSX was significantly lower in girls in both tests with EO and CE. Although there was no apparent significant difference of MSX between the Romberg test with EO and CE, a slight progression was observed in the test with CE. Analysis of variance of MSY with a single classification showed a significant effect of study options (p < 0.048, a significant interaction of gender and options of the study (p < 0.048, and a significant interaction of age and options of the study (p < 0.026. Analysis of variance of MSY showed a significant progression of MSY in the test with CE. Conclusions : Our research showed that balance with CE does not worsen, so it can be assumed that children have limited skills of using vision to maintain balance because there is a lack of appropriate coordination between vision and motor abilities, which in children are in development.

  7. LPHYS'13: 22nd International Laser Physics Workshop (Prague, 15-19 July 2013)

    Science.gov (United States)

    Yevseyev, Alexander V.

    2013-04-01

    The 22nd annual International Laser Physics Workshop (LPHYS'13) will be held from 15-19 July 2013 in the city of Prague, Czech Republic, at the Hotel Krystal and Czech Technical University hosted this year by the Institute of Physics ASCR and Czech Technical University in Prague. LPHYS'13 continues a series of workshops that took place in Dubna, 1992; Dubna/Volga river tour, 1993; New York, 1994; Moscow/Volga river tour (jointly with NATO SILAP Workshop), 1995; Moscow, 1996; Prague, 1997; Berlin, 1998; Budapest, 1999; Bordeaux, 2000; Moscow, 2001; Bratislava, 2002; Hamburg, 2003; Trieste, 2004; Kyoto, 2005; Lausanne, 2006; León, 2007; Trondheim, 2008; Barcelona, 2009; Foz do Iguaçu, 2010; Sarajevo, 2011; and Calgary, 2012. The total number of participants this year is expected to be about 400. In the past, annual participation was typically from over 30 countries. 2013 Chairmen: Miroslav Jelinek (Czech Republic) and Pavel P Pashinin (Russia) LPHYS'13 will offer eight scientific section seminars and one general symposium: Seminar 1 Modern Trends in Laser Physics Seminar 2 Strong Field & Attosecond Physics Seminar 3 Biophotonics Seminar 4 Physics of Lasers Seminar 5 Nonlinear Optics & Spectroscopy Seminar 6 Physics of Cold Trapped Atoms Seminar 7 Quantum Information Science Seminar 8 Fiber Optics Symposium Extreme Light Technologies, Science and Applications Abstract of your presentation A one-page abstract should contain: title; list of all co-authors (the name of the speaker underlined); affiliations; correspondence addresses including phone numbers, fax numbers, e-mail addresses; and the text of the abstract. Abstracts should be sent to the following co-chairs of the scientific seminars and the symposium: Kirill A Prokhorov (Seminar 1) E-mail: cyrpro@gpi.ru Mikhail V Fedorov (Seminar 2) E-mail: fedorov@ran.gpi.ru Sergey A Gonchukov (Seminar 3) E-mail: gonchukov@mephi.ru Ivan A Shcherbakov (Seminar 4) E-mail: gbufetova@lsk.gpi.ru Vladimir A Makarov (Seminar 5) E

  8. 15N and 13C abundances in marine environments with emphasis on biogeochemical structure of food networks

    International Nuclear Information System (INIS)

    Wada, E.

    1987-01-01

    Distributions of δ 15 N and δ 13 C for biogenic substances in the Antarctic Ocean and in the Otsuchi River estuary in Japan were investigated to construct isotope biogeochemical framework for assessing marine ecosystems. The isotopic compositions of phytoplankton were particularly low in the Antarctic Ocean. High nitrate and CO 2 concentrations in the surface sea waters, and the low light intensity seem to enhance the kinetic isotope fractionations that preferred the depletion of 15 N and 13 C in the algal body. A clear-cut linear relationship between animal δ 15 N and its trophic level was obtained in the Antarctic system. In the estuary, the variation of isotope ratios were principally governed by the mixing of land-derived organic matter, marine phytoplankton, and seagrasses. A food-chain effect of 15 N enrichment was also confirmed. An isotopically ordered structure was presented for a marine estuarine ecosystem. The isotopic abundances in a food network vary mainly because of the variation in 15 N and 13 C contents of primary producers grown under different environmental conditions and because of the enrichment of 15 N along food chains. (author)

  9. Species specific and environment induced variation of δ13C and δ15N in alpine plants

    Directory of Open Access Journals (Sweden)

    Yang eYang

    2015-06-01

    Full Text Available Stable carbon and nitrogen isotope signals in plant tissues integrate plant-environment interactions over long periods. In this study, we hypothesized that humid alpine life conditions are narrowing the scope for significant deviations from common carbon, water and nitrogen relations as captured by stable isotope signals. We explored the variation in δ13C and δ15N in 32 plant species from tissue type to ecosystem scale across a suite of locations at c. 2500 m elevation in the Swiss Alps. Foliar δ13C and δ15N varied among species by about 3-4 ‰ and 7-8 ‰ respectively. However, there was no overall difference in means of δ13C and δ15N for species sampled in different plant communities or when bulk plant dry matter harvests of different plant communities were compared. δ13C was found to be highly species specific, so that the ranking among species was mostly maintained across 11 habitats. However, δ15N varied significantly from place to place in all species (a range of 2.7 ‰ except in Fabaceae (Trifolium alpinum and Juncaceae (Luzula lutea. There was also a substantial variation among individuals of the same species collected next to each other. No difference was found in foliar δ15N of non-legumes, which were either collected next to or away from the most common legume, T. alpinum. δ15N data place Cyperaceae and Juncaceae, just like Fabaceae, in a low discrimination category, well separated from other families. Soil δ15N was higher than in plants and increased with soil depth. The results indicate a high functional diversity in alpine plants that is similar to that reported for low elevation plants. We conclude that the surprisingly high variation in δ13C and δ15N signals in the studied high elevation plants is largely species specific (genetic and insensitive to obvious environmental cues.

  10. Biosynthetic preparation of L-[13C]- and [15N]glutamate by Brevibacterium flavum

    International Nuclear Information System (INIS)

    Walker, T.E.; London, R.E.

    1987-01-01

    The biosynthesis of isotopically labeled L-glutamic acid by the microorganism Brevibacterium flavum was studied with a variety of carbon-13-enriched precursors. The purpose of this study was twofold: (i) to develop techniques for the efficient preparation of labeled L-glutamate with a variety of useful labeling patterns which can be used for other metabolic studies, and (ii) to better understand the metabolic events leading to label scrambling in these strains. B. flavum, which is used commercially for the production of monosodium glutamate, has the capability of utilizing glucose or acetate as a sole carbon source, and important criterion from the standpoint of developing labeling strategies. Unfortunately, singly labeled glucose precursors lead to excessive isotopic dilution which reduces their usefulness. Studies with [3- 13 C]pyruvate indicate that this problem can in principle be overcome by using labeled three-carbon precursors; however, conditions could not be found which would lead to an acceptable yield of isotopically labeled L-glutamate. In contrast, [1- 13 C]- or [2- 13 C]acetate provides relatively inexpensive, readily available precursors for the production of selectively labeled, high enriched L-glutamate. The preparation of L-[ 15 N]glutamate from [ 15 N]ammonium sulfate was carried out and is a very effective labeling strategy. Analysis of the isotopic distribution in labeled glutamate provides details about the metabolic pathways in these interesting organisms

  11. Stigmatised Learners: Mature-Age Students Negotiating University Culture

    Science.gov (United States)

    Mallman, Mark; Lee, Helen

    2016-01-01

    Research on the socially-situated nature of learning shows how practices and identities are affected by participation in communities, but very little is known about how mature-age students experience the relational dynamics of university. Based on data from a qualitative study of first-year students, we consider written accounts by older learners…

  12. [Suicidal behavior prevention for children under age 13: A systematic review].

    Science.gov (United States)

    Baux-Cazal, L; Gokalsing, E; Amadeo, S; Messiah, A

    2017-05-01

    Our objective was to review international literature on suicidal behavior prevention for children under age 13. We gathered all relevant articles on suicide prevention for children under 13. We researched all publications in the French and English languages in PubMed (MEDLINE), PsychINFO and SUDOC databases published until February 2014, with the keywords "child", "child preschool", "prevention and control", "suicide", and "suicide attempted". Publications were included if they described suicidal behavior prevention programs (suicide prevention programs, attempted-suicide prevention programs, suicidal ideation screening programs), and if the studies concerned children under age 13. We also included references cited in the articles if they were not already present in our searches but met inclusion criteria. Studies were excluded if they analyzed populations of children and adolescents without sub-analysis for children under age 13. A total of 350 potentially relevant articles were identified, 33 of which met the inclusion criteria, including 4 retrieved from articles' bibliography. Preventive measures against suicidal behavior for children under 13 exist and include: social programs, maltreatment prevention, curriculum-based suicide prevention programs, suicide screening in schools, gatekeepers, reduction of access of lethal means of suicide, suicide screening by primary care, and post-suicide intervention programs. Overall, the evidence was limited by methodological concerns, particularly a lack of RCTs. However, positive effects were found: school-based suicide prevention programs and gatekeepers increased knowledge about suicide and how to seek help, post-suicide programs helped to reduce psychological distress in the short term. One study showed a decreased risk of attempted-suicide after entry into the child welfare system. There are promising interventions but there is not enough scientific evidence to support any efficient preventive measure against

  13. Cigarette smoking and cigarette marketing exposure among students in selected African countries: Findings from the Global Youth Tobacco Survey.

    Science.gov (United States)

    Zhao, Luhua; Palipudi, Krishna M; Ramanandraibe, Nivo; Asma, Samira

    2016-10-01

    To investigate cigarette smoking prevalence and exposure to various forms of cigarette marketing among students in 10 African countries. We used data collected during 2009-2011 from the Global Youth Tobacco Survey (GYTS), a school-based cross-sectional survey of students aged 13-15years, to measure the prevalence of cigarette smoking and exposure to cigarette marketing; comparisons to estimates from 2005 to 2006 were conducted for five countries where data were available. Current cigarette smoking ranged from 3.4% to 13.6% among students aged 13-15 in the 10 countries studied, although use of tobacco products other than cigarettes was more prevalent in all countries except in Cote D'Ivoire. Cigarette smoking was higher among boys than girls in seven out of the 10 countries. Among the five countries with two rounds of surveys, a significant decrease in cigarette smoking prevalence was observed in Mauritania and Niger; these two countries also experienced a decline in three measures of cigarette marketing exposure. It is also possible that smoking prevalence might have risen faster among girls than boys. Cigarette smoking among youth was noticeable in 10 African countries evaluated, with the prevalence over 10% in Cote D'Ivoire, Mauritania, and South Africa. Cigarette marketing exposure varied by the types of marketing; traditional venues such as TV, outdoor billboards, newspapers, and magazines were still prominent. Published by Elsevier Inc.

  14. 15 CFR 13.8 - Opportunity to comment on proposed Federal financial assistance and direct Federal development.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Opportunity to comment on proposed Federal financial assistance and direct Federal development. 13.8 Section 13.8 Commerce and Foreign Trade Office of the Secretary of Commerce INTERGOVERNMENTAL REVIEW OF DEPARTMENT OF COMMERCE PROGRAMS AND ACTIVITIES § 13.8 Opportunity to comment on...

  15. Design of a school-based randomized trial to reduce smoking among 13 to 15-year olds, the X:IT study.

    Science.gov (United States)

    Andersen, Anette; Bast, Lotus Sofie; Ringgaard, Lene Winther; Wohllebe, Louise; Jensen, Poul Dengsøe; Svendsen, Maria; Dalum, Peter; Due, Pernille

    2014-05-28

    Adolescent smoking is still highly prevalent in Denmark. One in four 13-year olds indicates that they have tried to smoke, and one in four 15-year olds answer that they smoke regularly. Smoking is more prevalent in socioeconomically disadvantaged populations in Denmark as well as in most Western countries. Previous school-based programs to prevent smoking have shown contrasting results internationally. In Denmark, previous programs have shown limited or no effect. This indicates a need for developing a well-designed, comprehensive, and multi-component intervention aimed at Danish schools with careful implementation and thorough evaluation.This paper describes X:IT, a study including 1) the development of a 3-year school-based multi-component intervention and 2) the randomized trial investigating the effect of the intervention. The study aims at reducing the prevalence of smoking among 13 to 15-year olds by 25%. The X:IT study is based on the Theory of Triadic Influences. The theory organizes factors influencing adolescent smoking into three streams: cultural environment, social situation, and personal factors. We added a fourth stream, the community aspects. The X:IT program comprises three main components: 1) smoke-free school premises, 2) parental involvement including smoke-free dialogues and smoke-free contracts between students and parents, and 3) a curricular component. The study encompasses process- and effect-evaluations as well as health economic analyses. Ninety-four schools in 17 municipalities were randomly allocated to the intervention (51 schools) or control (43 schools) group. At baseline in September 2010, 4,468 year 7 students were eligible of which 4,167 answered the baseline questionnaire (response rate = 93.3%). The X:IT study is a large, randomized controlled trial evaluating the effect of an intervention, based on components proven to be efficient in other Nordic settings. The X:IT study directs students, their parents, and smoking

  16. Comparison of nutritional status of rural and urban school students receiving midday meals in schools of Bengaluru, India: a cross sectional study.

    Science.gov (United States)

    Shalini, C N; Murthy, N S; Shalini, S; Dinesh, R; Shivaraj, N S; Suryanarayana, S P

    2014-01-01

    The objective of the study was to assess the impact of the mid day meal program by assessing the nutritional status of school students aged 5-15 years receiving midday meals in rural schools and compare them with those in urban schools in Bengaluru, India. This cross sectional study involved a sample of 4378 students from government and aided schools. Weight and height were measured and compared with ''means'' and ''percentiles'' of expected standards as endorsed by the Indian Association of Pediatrics. Regression coefficients were also estimated to assess the rate of growth. In all age groups and in both sexes, the observed mean weight and height were below the expected standards. The study findings showed that 13.8% and 13.1% of the studied students were underweight and stunted, respectively (below the third percentile for weight and height for age). A higher proportion of rural students were below the third percentile for both weight and height compared with urban students (weight: 16.3% and 11.5%; height: 17.0% and 10.0%; P nutrition in children and indirectly impact school performance, attendance and literacy.

  17. 15 CFR 20.1 - The purpose of DOC's age discrimination regulations.

    Science.gov (United States)

    2010-01-01

    ... NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General § 20... basis of age in programs or activities receiving Federal financial assistance. The Act and the general... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false The purpose of DOC's age...

  18. 15 CFR 20.4 - Rules against age discrimination.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Rules against age discrimination. 20.4 Section 20.4 Commerce and Foreign Trade Office of the Secretary of Commerce NONDISCRIMINATION ON THE BASIS..., be excluded from participation in, be denied the benefits of, or be subjected to discrimination under...

  19. Overweight, body image and bullying--an epidemiological study of 11- to 15-years olds

    DEFF Research Database (Denmark)

    Brixval, Carina S; Rayce, Signe L B; Rasmussen, Mette

    2012-01-01

    : The regression analyses showed that overweight and obese students were more exposed to bullying than their normal weight peers. Among boys, odds ratios (ORs) for exposure to bullying were 1.75 (1.18-2.61) in overweight and 1.98 (0.79-4.95) in obese boys compared with normal weight. Among girls, the corresponding...... contribution to the international cross-sectional research project Health Behaviour in School-aged Children (HBSC) 2002 was used. Data were assessed from questionnaires and 4781 students aged 11-, 13- and 15-years old were included in the analyses. Logistic regression was used for the analyses. RESULTS...... ORs were 1.89 (1.25-2.85) in overweight and 2.74 (0.96-7.82) in obese girls. The mediation analyses showed that body image fully mediated the associations between weight status and exposure to bullying in both boys and girls. CONCLUSIONS: This study shows that overweight and obese boys and girls...

  20. Social background, bullying, and physical inactivity: National study of 11- to 15-year-olds.

    Science.gov (United States)

    Henriksen, P W; Rayce, S B; Melkevik, O; Due, P; Holstein, B E

    2016-10-01

    More children from lower social backgrounds are physically inactive than those from higher ones. We studied whether bullying was a mediating factor between lower social background and physical inactivity. We also examined the combined effect of low social class and exposure to bullying on physical inactivity. The Danish sample of the Health Behaviour in School-aged Children (HBSC) study 2006 included 6269 schoolchildren in three age groups: 11-, 13-, and 15-year-olds from a random sample of 80 schools. The students answered the internationally standardized HBSC questionnaire. The applied definition leaves 4.0% in the category physically inactive. The sex and age-adjusted OR (95% CI) for physical inactivity was 2.10 (1.39-3.18) among students with low social class and unclassifiable 3.53 (2.26-5.53). Exposure to bullying was associated with physical inactivity, sex and age-adjusted OR = 2.39 (1.67-3.41). Exposure to bullying did not explain the association between social class and physical inactivity. The association between social class and physical inactivity was more pronounced among participants also exposed to bullying. In conclusion, there was a significantly increased odds ratio for physical inactivity among students from lower social classes and for students exposed to bullying. There was a combined effect of low social class and bullying on physical inactivity. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  1. Coupling fallout 210Pb and stables isotopes (δ13C, δ15N) for catchment urbanization reconstruction in southeastern coastal zone of Brazil

    International Nuclear Information System (INIS)

    Cerda, Mauricio; Macario, Kita Damasio; Roberto Meigikos dos Anjos; Universidade Federal Fluminense; Lamego, Fernando; Universidade Federal Fluminense

    2016-01-01

    Eutrophication history was reconstructed by bulk organic and inorganic proxies (C, N, P) and isotope (δ 13 C and δ 15 N) analysis constrained by geochronological model derived from fallout 210 Pb in Brazilian coastal lagoon. The sedimentary record spanning the last four decades showed impact of urbanization starting from 1970s. These changes were marked by increase of TN, TP, IP fluxes that were significantly correlated with population growth. Significant covariation of C:N, MDP and δ 15 N along age-depth profiles provided linkage with sedimentation rates, serving as an independent time marker for geochronology and validating use of 210 Pb dating model based on constant initial concentration. (author)

  2. Socio-motivational moderators-two sides of the same coin? Testing the potential buffering role of socio-motivational relationships on achievement drive and test anxiety among German and Canadian secondary school students.

    Science.gov (United States)

    Hoferichter, Frances; Raufelder, Diana; Eid, Michael

    2015-01-01

    The current cross-national study investigates the potential buffering role of socio-motivational relationships for the association of achievement drive (AD) and test anxiety (TX) in secondary school students from Canada and Germany. One thousand and eighty-eight students (54% girls, M age = 13.71, SD = 0.53, age span 12-15 years) from the state of Brandenburg and 389 students from Quebéc (55.9% girls, M age = 13.43, SD = 0.82, age span 12-16 years) were asked about their socio-motivational relationships with their teachers and peers, their drive for achievement, and TX. Multigroup latent moderated structural equations were conducted to test for the moderator role of socio-motivational relationships that would buffer feelings of TX related to the drive for achievement. The analyses revealed the two-sided role socio-motivational relationships can have for students with different levels of AD; intensifying or mitigating feelings of TX. Thereby, the results of this study extend the buffering hypothesis by Cohen and Wills (1985). Cross-national differences between Canada and Germany were found concerning the studied moderators on the association of AD and TX: While for German students teacher-student relationships acted as moderator, for Canadian students student-student relationships and teachers acting as positive motivators displayed a moderator role.

  3. Variation in hair δ13C and δ15N values in long-tailed macaques (Macaca fascicularis) from Singapore

    Science.gov (United States)

    Schillaci, Michael A.; Castellini, J. Margaret; Stricker, Craig A.; Jones-Engel, Lisa; Lee, Benjamin P.Y.-H.

    2014-01-01

    Much of the primatology literature on stable isotope ratios of carbon (δ13C) and nitrogen (δ15N) has focused on African and New World species, with comparatively little research published on Asian primates. Here we present hair δ13C and δ15N isotope values for a sample of 33 long-tailed macaques from Singapore. We evaluate the suggestion by a previous researcher that forest degradation and biodiversity loss in Singapore have led to a decline in macaque trophic level. The results of our analysis indicated significant spatial variability in δ13C but not δ15N. The range of variation in δ13C was consistent with a diet based on C3 resources, with one group exhibiting low values consistent with a closed canopy environment. Relative to other macaque species from Europe and Asia, the macaques from Singapore exhibited a low mean δ13C value but mid-range mean δ15N value. Previous research suggesting a decline in macaque trophic level is not supported by the results of our study.

  4. http://dx.doi.org/10.4314/og.v13i 1.15

    African Journals Online (AJOL)

    Dean SPGS NAU

    http://dx.doi.org/10.4314/og.v13i 1.15. Abstract. In Nigeria, there are three main religions recognised by the people;. Christianity, Islam and the Indigenous religion. These religions have differences that have brought about unrest as the tolerance level has got to a point of polarity. The various unrests have led to national.

  5. 7 CFR 15f.13 - What is the function of the ALJ and who may communicate with him?

    Science.gov (United States)

    2010-01-01

    ... communicate with him? 15f.13 Section 15f.13 Agriculture Office of the Secretary of Agriculture ADJUDICATIONS... What is the function of the ALJ and who may communicate with him? (a) What are the powers of the ALJ... time between the assignment of a hearing to him or her and the issuance of a proposed determination...

  6. Changing negative stereotypes regarding aging in undergraduate nursing students.

    Science.gov (United States)

    Sarabia-Cobo, C M; Castanedo Pfeiffer, C

    2015-09-01

    The aim of this study was to explore the modification of stereotypes and myths regarding aging among third-year nursing students before and after undergoing an Aging Nursing course. A within-subject repeated-measures descriptive study was conducted. The Negative Stereotypes Questionnaire about Aging (CENVE) was used. The overall prevalence of negative stereotypes was 62.0% pre-intervention (P1) and 12.3% post-intervention (P2) measured; these values were 63.5% (P1) and 9.2% (P2) for the health factor, 43.1% (P1) and 4.9% (P2) for the motivation and social factors and 58.3% (P1) and 3.8% (P2) for the character-personality factor. Paired Student's t tests confirmed that the differences were statistically significant. There was a high prevalence of negative stereotypes toward aging among the nursing students, even though they had conducted clinical practice and were in their third year. The course was demonstrated to be effective in modifying these stereotypes. The proper training of future professionals markedly contributes the dispensation of proper care and the eradication of ageism, which remains prevalent in the healthcare system. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. A new approach to age-period-cohort analysis using partial least squares regression: the trend in blood pressure in the Glasgow Alumni cohort.

    Directory of Open Access Journals (Sweden)

    Yu-Kang Tu

    2011-04-01

    Full Text Available Due to a problem of identification, how to estimate the distinct effects of age, time period and cohort has been a controversial issue in the analysis of trends in health outcomes in epidemiology. In this study, we propose a novel approach, partial least squares (PLS analysis, to separate the effects of age, period, and cohort. Our example for illustration is taken from the Glasgow Alumni cohort. A total of 15,322 students (11,755 men and 3,567 women received medical screening at the Glasgow University between 1948 and 1968. The aim is to investigate the secular trends in blood pressure over 1925 and 1950 while taking into account the year of examination and age at examination. We excluded students born before 1925 or aged over 25 years at examination and those with missing values in confounders from the analyses, resulting in 12,546 and 12,516 students for analysis of systolic and diastolic blood pressure, respectively. PLS analysis shows that both systolic and diastolic blood pressure increased with students' age, and students born later had on average lower blood pressure (SBP: -0.17 mmHg/per year [95% confidence intervals: -0.19 to -0.15] for men and -0.25 [-0.28 to -0.22] for women; DBP: -0.14 [-0.15 to -0.13] for men; -0.09 [-0.11 to -0.07] for women. PLS also shows a decreasing trend in blood pressure over the examination period. As identification is not a problem for PLS, it provides a flexible modelling strategy for age-period-cohort analysis. More emphasis is then required to clarify the substantive and conceptual issues surrounding the definitions and interpretations of age, period and cohort effects.

  8. Facebook Age Display and Alcohol Use among College Students

    Science.gov (United States)

    Wilner, Molly; Kerr, Bradley; Moreno, Megan

    2018-01-01

    Background: This study aimed to investigate the relationship between Facebook age presentation, Facebook alcohol displays, and alcohol related risk factors among college students. Methods: Students from two universities in the United States enrolled and accepted a researcher's Facebook friend request. Participant's Facebook profiles were evaluated…

  9. 41 CFR 302-15.13 - What are the income tax consequences when my agency pays for my property management services?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What are the income tax consequences when my agency pays for my property management services? 302-15.13 Section 302-15.13 Public....13 What are the income tax consequences when my agency pays for my property management services? When...

  10. Levels of 16O near 13 MeV excitation from 15N+p reactions

    International Nuclear Information System (INIS)

    Bray, K.H.; Frawley, A.D.; Ophel, T.R.; Barker, F.C.

    1977-02-01

    Angular distributions, a O 0 excitation function and Doppler-broadened γ-ray profiles for the reaction 15 N(p,α 1 γ), and angular distributions for the 15 N(p,αsub(o)) reaction, have been measured for proton energies from about 900 to 1250 keV. These data, together with analysing powers from the 15 N(p,αsub(o)) reaction with polarized protons, have been satisfactorily fitted by means of R-matrix theory, in terms of the known levels of 16 O in the 13 MeV region together with background contributions. (Author)

  11. [Sexual intercourse debut and associated factors in Mexican students aged 14-19 years in public schools].

    Science.gov (United States)

    Rivera-Rivera, Leonor; Leyva-López, Ahidée; García-Guerra, Armando; de Castro, Filipa; González-Hernández, Dolores; de Los Santos, Lilia Margarita

    2016-01-01

    To estimate the mean age of sexual intercourse debut (SID) and associated family and individual factors in 14-19-year-olds of both sexes in the 32 states of Mexico in 2007. A cross-sectional study was conducted of a representative sample of 9,893 students aged between 14 and 19 years old. The data were collected through a self-administered, anonymous and voluntary questionnaire. Logistic regression models were used to estimate odds ratios (OR) with 95% confidence intervals (95%CI) by category: no SID, SID at 10-15 years and SID at 16-19 years. The national mean age of SID was 16 years, being 15 years for boys (95%CI: 15.88-16.11) and 16 years for girls (95%CI: 15.26-15.42). Factors associated with SID in boys were disadvantaged socioeconomic level (OR=0.66; 95%CI: 0.46-0.94), living with parents (OR=0.65; 95%CI: 0.56-0.75), less offensive communication between parents and boys/girls (OR=0.66; 95%CI: 0.57-0.77), and high social self-esteem (OR=1.68; 95%CI: 1.35-1.77). Factors associated with SID in girls were traditional gender beliefs (OR=0.49; 95%CI: 0.32-0.74), high depressive symptoms (OR=1.88; 95%CI: 1.19-2.99), and high family self-esteem (OR= 0.50; 95%CI: 0.38-0.65). In Mexico, SID occurred early in boys. In addition, the findings of this study show that in Mexico, the age of SID and associated factors differ in boys and girls. The age of SID is strongly influenced by gender and cultural beliefs. Copyright © 2015 SESPAS. Published by Elsevier Espana. All rights reserved.

  12. Afforestation impacts microbial biomass and its natural {sup 13}C and {sup 15}N abundance in soil aggregates in central China

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Junjun; Zhang, Qian; Yang, Fan; Lei, Yao; Zhang, Quanfa; Cheng, Xiaoli, E-mail: xlcheng@fudan.edu.cn

    2016-10-15

    We investigated soil microbial biomass and its natural abundance of δ{sup 13}C and δ{sup 15}N in aggregates (> 2000 μm, 250–2000 μm, 53–250 μm and < 53 μm) of afforested (implementing woodland and shrubland plantations) soils, adjacent croplands and open area (i.e., control) in the Danjiangkou Reservoir area of central China. The afforested soils averaged higher microbial biomass carbon (MBC) and nitrogen (MBN) levels in all aggregates than in open area and cropland, with higher microbial biomass in micro-aggregates (< 250 μm) than in macro-aggregates (> 2000 μm). The δ{sup 13}C of soil microbial biomass was more enriched in woodland soils than in other land use types, while δ{sup 15}N of soil microbial biomass was more enriched compared with that of organic soil in all land use types. The δ{sup 13}C and δ{sup 15}N of microbial biomass were positively correlated with the δ{sup 13}C and δ{sup 15}N of organic soil across aggregates and land use types, whereas the {sup 13}C and {sup 15}N enrichment of microbial biomass exhibited linear decreases with the corresponding C:N ratio of organic soil. Our results suggest that shifts in the natural {sup 13}C and {sup 15}N abundance of microbial biomass reflect changes in the stabilization and turnover of soil organic matter (SOM) and thereby imply that afforestation can greatly impact SOM accumulation over the long-term. - Highlights: • Afforested soils averaged higher microbial biomass in all aggregates than cropland. • Microbial biomass was higher in micro-aggregates than in macro-aggregates. • δ{sup 13}C and δ{sup 15}N of microbe positively correlated with δ{sup 13}C and δ{sup 15}N of organic soil. • {sup 13}C and {sup 15}N enrichment of microbe was negatively related to with soil C:N ratio.

  13. Recurrent microdeletions at 15q11.2 and 16p13.11 predispose to idiopathic generalized epilepsies

    DEFF Research Database (Denmark)

    de Kovel, Carolien G F; Trucks, Holger; Helbig, Ingo

    2010-01-01

    could be examined in 14 families. While 10 microdeletions were inherited (seven maternal and three paternal transmissions), four microdeletions occurred de novo at 15q13.3 (n = 1), 16p13.11 (n = 2) and 22q11.2 (n = 1). Eight of the transmitting parents were clinically unaffected, suggesting...... syndromes. The candidate microdeletions were assessed by high-density single nucleotide polymorphism arrays in 1234 patients with idiopathic generalized epilepsy from North-western Europe and 3022 controls from the German population. Microdeletions were validated by quantitative polymerase chain reaction.......2 (odds ratio = 4.9; 95% confidence interval 1.8-13.2; P = 4.2 x 10(-4)) and 16p13.11 (odds ratio = 7.4; 95% confidence interval 1.3-74.7; P = 0.009). Including nine patients with idiopathic generalized epilepsy in this cohort with known 15q13.3 microdeletions (IGE/control: 9/0), parental transmission...

  14. Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders.

    Directory of Open Access Journals (Sweden)

    Anthony R Isles

    2016-05-01

    Full Text Available Duplications at 15q11.2-q13.3 overlapping the Prader-Willi/Angelman syndrome (PWS/AS region have been associated with developmental delay (DD, autism spectrum disorder (ASD and schizophrenia (SZ. Due to presence of imprinted genes within the region, the parental origin of these duplications may be key to the pathogenicity. Duplications of maternal origin are associated with disease, whereas the pathogenicity of paternal ones is unclear. To clarify the role of maternal and paternal duplications, we conducted the largest and most detailed study to date of parental origin of 15q11.2-q13.3 interstitial duplications in DD, ASD and SZ cohorts. We show, for the first time, that paternal duplications lead to an increased risk of developing DD/ASD/multiple congenital anomalies (MCA, but do not appear to increase risk for SZ. The importance of the epigenetic status of 15q11.2-q13.3 duplications was further underlined by analysis of a number of families, in which the duplication was paternally derived in the mother, who was unaffected, whereas her offspring, who inherited a maternally derived duplication, suffered from psychotic illness. Interestingly, the most consistent clinical characteristics of SZ patients with 15q11.2-q13.3 duplications were learning or developmental problems, found in 76% of carriers. Despite their lower pathogenicity, paternal duplications are less frequent in the general population with a general population prevalence of 0.0033% compared to 0.0069% for maternal duplications. This may be due to lower fecundity of male carriers and differential survival of embryos, something echoed in the findings that both types of duplications are de novo in just over 50% of cases. Isodicentric chromosome 15 (idic15 or interstitial triplications were not observed in SZ patients or in controls. Overall, this study refines the distinct roles of maternal and paternal interstitial duplications at 15q11.2-q13.3, underlining the critical importance of

  15. Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders

    Science.gov (United States)

    Isles, Anthony R.; Ingason, Andrés; Lowther, Chelsea; Gawlick, Micha; Stöber, Gerald; Potter, Harry; Georgieva, Lyudmila; Pizzo, Lucilla; Ozaki, Norio; Kushima, Itaru; Ikeda, Masashi; Iwata, Nakao; Levinson, Douglas F.; Gejman, Pablo V.; Shi, Jianxin; Sanders, Alan R.; Duan, Jubao; Sisodiya, Sanjay; Costain, Gregory; Degenhardt, Franziska; Giegling, Ina; Rujescu, Dan; Hreidarsson, Stefan J.; Saemundsen, Evald; Ahn, Joo Wook; Ogilvie, Caroline; Stefansson, Hreinn; Stefansson, Kari; O’Donovan, Michael C.; Owen, Michael J.; Bassett, Anne; Kirov, George

    2016-01-01

    Duplications at 15q11.2-q13.3 overlapping the Prader-Willi/Angelman syndrome (PWS/AS) region have been associated with developmental delay (DD), autism spectrum disorder (ASD) and schizophrenia (SZ). Due to presence of imprinted genes within the region, the parental origin of these duplications may be key to the pathogenicity. Duplications of maternal origin are associated with disease, whereas the pathogenicity of paternal ones is unclear. To clarify the role of maternal and paternal duplications, we conducted the largest and most detailed study to date of parental origin of 15q11.2-q13.3 interstitial duplications in DD, ASD and SZ cohorts. We show, for the first time, that paternal duplications lead to an increased risk of developing DD/ASD/multiple congenital anomalies (MCA), but do not appear to increase risk for SZ. The importance of the epigenetic status of 15q11.2-q13.3 duplications was further underlined by analysis of a number of families, in which the duplication was paternally derived in the mother, who was unaffected, whereas her offspring, who inherited a maternally derived duplication, suffered from psychotic illness. Interestingly, the most consistent clinical characteristics of SZ patients with 15q11.2-q13.3 duplications were learning or developmental problems, found in 76% of carriers. Despite their lower pathogenicity, paternal duplications are less frequent in the general population with a general population prevalence of 0.0033% compared to 0.0069% for maternal duplications. This may be due to lower fecundity of male carriers and differential survival of embryos, something echoed in the findings that both types of duplications are de novo in just over 50% of cases. Isodicentric chromosome 15 (idic15) or interstitial triplications were not observed in SZ patients or in controls. Overall, this study refines the distinct roles of maternal and paternal interstitial duplications at 15q11.2-q13.3, underlining the critical importance of maternally

  16. Social inequalities in changes in health-related behaviour among Slovak adolescents aged between 15 and 19: A longitudinal study

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    Sleskova Maria

    2008-02-01

    Full Text Available Abstract Background Lower socioeconomic position is generally associated with higher rates of smoking and alcohol consumption and lower levels of physical activity. Health-related behaviour is usually established during late childhood and adolescence. The aim of this study is to explore changes in health-related behaviour in a cohort of adolescents aged between 15 and 19, overall and by socioeconomic position. Methods The sample consisted of 844 first-year students (42.8% males, baseline in 1998 – mean age 14.9, follow-up in 2002 – mean age 18.8 from 31 secondary schools located in Kosice, Slovakia. This study focuses on changes in adolescents' smoking, alcohol use, experience with marijuana and lack of physical exercise with regard to their socioeconomic position. Four indicators of socioeconomic position were used – adolescents' current education level and employment status, and the highest education level and highest occupational status of their parents. We first made cross tabulations of HRB with these four indicators, using McNemar's test to assess differences. Next, we used logistic regression to assess adjusted associations, using likelihood ratio tests to assess statistical significance. Results Statistically significant increases were found in all health-related behaviours. Among males, the most obvious socioeconomic gradient was found in smoking, both at age 15 and at 19. Variations in socioeconomic differences in health-related behaviour were more apparent among females. Although at age 15, almost no socioeconomic differences in health-related behaviour were found, at age 19 differences were found for almost all socioeconomic indicators. Among males, only traditional socioeconomic gradients were found (the lower the socioeconomic position, the higher the prevalence of potentially harmful health-related behaviour, while among females reverse socioeconomic gradients were also found. Conclusion We confirmed an increase in unhealthy

  17. Leaf allocation patterns and 13C and 15N natural abundances of tropical lianas (Passiflora sp.) as dependent on external climbing support.

    Science.gov (United States)

    Werth, Martin; Spiegel, Ann-Kathrin; Kazda, Marian

    2013-01-01

    The transformation from self-supporting lianas to host-supported climbing lianas is related to re-allocation of biomass and nutrients among plant organs. Therefore, first, variations in leaf mass per area (LMA), leaf carbon and nitrogen allocation and (13)C and (15)N natural abundances were analysed among three tropical Passiflora species (P. edulis, P. ligularis, and P. tripartita) in a greenhouse study. Second, the influence of a climbing support was considered for each species and parameter. P. ligularis leaves were most enriched in (13)C in both treatments when compared with the other two species. This enrichment was caused by a high LMA, which is related to a high internal resistance to CO(2) diffusion. For P. edulis and P. tripartita, δ(13)C was additionally increasing with nitrogen content per area. Generally, there were no differences when considering carbon and nitrogen allocation to leaves of host-supported and self-supporting lianas. The only hints towards increased investment into leaves after the transition from self-supporting to host-supported stages could be seen by a trend to increased leaf areas and masses. δ(13)C values of supported P. edulis or P. tripartita plants were significantly increasing faster than those of non-supported plants once the interactions of leaf mass or nitrogen content per area were accounted for. Hence, the offer of a climbing support had only a minor impact on δ(13)C or δ(15)N values in vitro, but this could be different with increasing age of lianas in vivo.

  18. Teaching Problem Solving Skills to Elementary Age Students with Autism

    Science.gov (United States)

    Cote, Debra L.; Jones, Vita L.; Barnett, Crystal; Pavelek, Karin; Nguyen, Hoang; Sparks, Shannon L.

    2014-01-01

    Students with disabilities need problem-solving skills to promote their success in solving the problems of daily life. The research into problem-solving instruction has been limited for students with autism. Using a problem-solving intervention and the Self Determined Learning Model of Instruction, three elementary age students with autism were…

  19. Loss of heterozygosity at 11p13 and 11p15 in Wilms tumor: a study of 22 cases from India.

    Science.gov (United States)

    Sigamani, Elanthenral; Wari, Mohammad Nahidul; Iyer, Venkateswaran K; Agarwala, Sandeep; Sharma, Arundhati; Bakhshi, Sameer; Dinda, Amit

    2013-03-01

    11p13 and 11p15 loss of heterozygosity (LOH) in Wilms tumor (WT), the commonest molecular pathogenetic event in WT, shows variation in different parts of the world. The present study looked for the presence of 11p13 and 11p15 LOH as well as nephrogenic rests in WT occurring in India. Twenty-two cases of WT were subjected to thorough pathological examination for presence of nephrogenic rests. Fresh frozen tissue was evaluated for LOH at 11p13 and 11p15, using PCR for microsatellite markers. Among twenty-two consecutive cases of WT, 20 were unilateral and 2 were bilateral. 6/22 showed LOH at 11p13 (27.7 %) and 1/22 showed LOH at 11p15 (4.54 %). 2/22 cases showed presence of nephrogenic rests. One of the cases with LOH at 11p13 had intralobar nephrogenic rest in the adjacent kidney. One specimen had perilobar nephrogenic rest in the adjacent kidney but did not show LOH for either 11p13 or 11p15 in the tumor. LOH at 11p13 is seen in 27.27 % of WT in India, which is similar to reports in the English language literature. LOH at 11p15 was seen in 4.54 % of WT, which is lower than that reported from Western subjects.

  20. Depressive Symptoms among Fourth Form Students in St. Kitts and Nevis High Schools

    Directory of Open Access Journals (Sweden)

    Gillian A. Lowe

    2009-01-01

    Full Text Available There has been limited research on depressive symptoms among high school students in St. Kitts and Nevis. This project examines levels of depressive symptoms among fourth form (grade 10 students attending all high schools in St. Kitts and Nevis. Students enrolled in the fourth form during the 2006/2007 academic year in all high schools were administered the Beck Depression Inventory II (BDI-II. A near census of the students was conducted (n = 744 students; 50.4% females, 47.6% males, and 2% no gender reported; age 13–19 years, mean = 15.5 ± 0.8 years. Six in every ten students (62.1% reported some symptoms of depression, with 14.8% reporting moderate to severe and 9.7% reporting severe symptoms of depression. Females reported significantly higher BDI-II scores (t(727 = 7.11, p < 0.01 with 70% of females reporting some level of depressive symptoms compared with 52% of their male counterparts (X2(1 = 24.6, p < 0.05. Additionally, 34% of females were in the moderate to severe or severe range of depressive symptoms, while 15% of males were in the same range. Students who were older than expected for their grade (i.e., 17 years or older reported significantly higher BDI-II scores (F(2,740 = 2.88, p < 0.05 than students who were younger or at the expected age (i.e., 14–16 years. Students whose mothers had a high school or postsecondary education reported significantly lower levels of depressive symptoms than students whose mothers had less than a high school education (F(3, 637, = 4.23, p < 0.05. Symptoms of depression among fourth form students in St. Kitts and Nevis are a prevalent problem that is influenced by students’ age, gender, and social class as indicated by maternal education.

  1. Suicide mortality trends in young people aged 15 to 19 years in Lithuania.

    Science.gov (United States)

    Strukcinskiene, B; Andersson, R; Janson, S

    2011-11-01

    This paper considers the suicide mortality trends from 1990-2009 in young people aged 15 to 19 years in Lithuania. Suicide and injury mortality data, plus mortality data from all causes, were used to compare the trend lines. Suicide mortality rate in young people aged 15-19 years and in all population showed a rising trend from 1990, and then a decreasing trend from 2002 year. This trend was significant exclusively in boys. When comparing suicide deaths as a percentage of injury deaths and of all deaths in the age group 15-19 years, rising trends for boys were evident, whilst in girls, there was no evidence of change. In Lithuania, from early 1990s, the frequency of suicide increased amongst adults and young people aged 15-19 years. After 2002, a decrease in deaths by suicide was observed both for the whole population and for young people aged 15-19 years. The rise and fall was obvious for boys. The reasons for different trends may have been influenced by the political and socioeconomic instability in the 1990-2002 period, and the socioeconomic stability, together with active preventive measures, from 2002. Although the consumption of modern Selective serotonin reuptake inhibitors (SSRIs) increased during the same time, suicide mortality was again high during the economic crisis in 2008-2009. © 2011 The Author(s)/Acta Paediatrica © 2011 Foundation Acta Paediatrica.

  2. Age dynamic of physical condition changes in pre-school age girls, schoolgirls and students, living in conditions of Eastern Siberia

    Directory of Open Access Journals (Sweden)

    V.Y. Lebedinskiy

    2017-12-01

    Full Text Available Purpose: to analyze dynamic of physical condition, considering sex (females and age of the tested, living in region with unfavorable ecology. Material: we studied pre school age girls (n=1580, age 4-7 years. In the research we did not include children with chronic diseases, who were under observation. We tested schoolgirls (n=3211, age 7-17 years and girl students (n=5827, age 17-21 years, 1-4 years of study. Girl students were divided into five age groups: from 17 to 21 years. All participants lived in conditions of Eastern Siberia (Irkutsk. This region is characterized by unfavorable ecology and climate geographic characteristics. Results: in dynamic of physical condition of pre-school girls, schoolgirls and students we marked out three substantial periods of it characteristics' changes. Age 7-8 years is critical (transition from 1st to 2nd stage. The least values of these characteristics are found in older (after 17-18 years ages. In students we observed relative stabilization of these indicators. Conclusions: the received results shall be considered in building physical education training process in pre-school educational establishments, secondary comprehensive schools and higher educational establishments.

  3. THE PREVALENCE OF SMOKING AMONG THE STUDENTS OF MERAM APPRENTICESHIP SCHOOL

    Directory of Open Access Journals (Sweden)

    Ruhusen KUTLU

    2006-12-01

    Full Text Available The purpose of this study is to describe the prevalence of smoking among the students of Meram Apprenticeship School and to analyze the affecting factors. This descriptive and cross-sectional study was carried out among 192 students who educated at Meram Apprenticeship School during 2004-2005 academic years. Of 192 students whom participated in this study, 95.8 % ( n= 184 were male, and 4.2 % (n= 8 were female, minimum age was 15, maximum age was 20 (median value= 17 years. When the smoking status was evaluated, 50.5 % (n= 97 were ever-smokers, 7.3 % (n= 14 were ex-smokers, 42.2 % (n=81 were never smokers. The lowest age at starting smoking was 7 years, the highest age was 18 years and the median value was 13 years. When the reasons to start smoking were analysed, 41 students of 97 current smokers stated that they had started smoking because of affecting of social environment and friend groups (40.6 %, n=41, affectation and enthusiasm (27.7 %, n=28, stress and anxiety (21.8 % n=22. According to Fagerstrom criterion, 43 students (42.2 % were assessed very low addictive level, 23 students (n=22.5% were high addictive level. Our results showed that the prevalence of smoking among the students of Meram Apprenticeship School was an important matter. [TAF Prev Med Bull 2006; 5(6.000: 424-433

  4. Vital Signs: Births to Teens Aged 15–17 Years — United States, 1991–2012

    Science.gov (United States)

    Cox, Shanna; Pazol, Karen; Warner, Lee; Romero, Lisa; Spitz, Alison; Gavin, Lorrie; Barfield, Wanda

    2014-01-01

    Background Teens who give birth at age 15–17 years are at increased risk for adverse medical and social outcomes of teen pregnancy. Methods To examine trends in the rate and proportion of births to teens aged 15–19 years that were to teens aged 15–17 years, CDC analyzed 1991–2012 National Vital Statistics System data. National Survey of Family Growth (NSFG) data from 2006–2010 were used to examine sexual experience, contraceptive use, and receipt of prevention opportunities among female teens aged 15–17 years. Results During 1991–2012, the rate of births per 1,000 teens declined from 17.9 to 5.4 for teens aged 15 years, 36.9 to 12.9 for those aged 16 years, and 60.6 to 23.7 for those aged 17 years. In 2012, the birth rate per 1,000 teens aged 15–17 years was higher for Hispanics (25.5), non-Hispanic blacks (21.9), and American Indians/Alaska Natives (17.0) compared with non-Hispanic whites (8.4) and Asians/Pacific Islanders (4.1). The rate also varied by state, ranging from 6.2 per 1,000 teens aged 15–17 years in New Hampshire to 29.0 in the District of Columbia. In 2012, there were 86,423 births to teens aged 15–17 years, accounting for 28% of all births to teens aged 15–19 years. This percentage declined from 36% in 1991 to 28% in 2012 (pteens aged 15–17 years received formal sex education on birth control or how to say no to sex, 24% had not spoken with parents about either topic; among sexually experienced female teens, 83% reported no formal sex education before first sex. Among currently sexually active female teens (those who had sex within 3 months of the survey) aged 15–17 years, 58% used clinical birth control services in the past 12 months, and 92% used contraception at last sex; however, only 1% used the most effective reversible contraceptive methods. Conclusions Births to teens aged 15–17 years have declined but still account for approximately one quarter of births to teens aged 15–19 years. Implications for public health

  5. Depression and suicidal ideation among Canadians aged 15 to 24.

    Science.gov (United States)

    Findlay, Leanne

    2017-01-18

    Among Canadians aged 15 to 24, the rate of depression is higher than at any other age, and suicide is the second leading cause of death. The current study provides detailed information about depression and suicidal ideation among young Canadians, including their use of mental health support. Data from the 2012 Canadian Community Health Survey-Mental Health (CCHS-MH) were used to describe rates and experiences of depression and suicidal ideation among Canadians aged 15 to 24, including psychosocial characteristics of those who had depression or reported suicidal thoughts. Characteristics associated with seeking professional support were also examined. About 11% of Canadians aged 15 to 24 had experienced depression in their lifetime; 7%, in the past year. Approximately 14% reported having had suicidal thoughts in their lifetime; 6%, in the past year. Lifetime depression and suicidal thoughts were moderately correlated (r = .34, p ⟨ .001). Individuals with lifetime depression had more than four times the odds of seeking professional support in the previous year, compared with those who did not have lifetime depression; those with lifetime suicidal thoughts had more than three times the odds of seeking professional support, compared with those who did not have lifetime suicidal thoughts. Psychosocial factors such as negative social interactions and lower perceived ability to deal with stress were associated with depression and suicidal thoughts, although these associations differed for males and females. The findings suggest that many young Canadians have depression and/or suicidal thoughts. Their odds of seeking professional support are significantly high.

  6. Changes in consumption of added sugars from age 13 to 30 years: a systematic review and meta-analysis of longitudinal studies.

    Science.gov (United States)

    Winpenny, E M; Penney, T L; Corder, K; White, M; van Sluijs, E M F

    2017-11-01

    Added sugar intake during adolescence has been associated with weight gain and cardiometabolic risk factors. Moreover, dietary habits may persist into adulthood, increasing chronic disease risk in later life. This systematic review investigated changes in intake of added sugars between the ages of 13 and 30 years. Literature databases were searched for longitudinal studies of diet during adolescence or early adulthood. Retrieved articles were screened for studies including multiple measures of intake of sugars or sugary foods from cohort participants between the ages of 13 and 30. Data were analysed using random-effects meta-analysis, by the three main nutrient and food group categories identified (PROSPERO: CRD42015030126). Twenty-four papers reported longitudinal data on intake of added sugar or sucrose (n = 6), sugar-sweetened beverages (SSBs) (n = 20) and/or confectionery (n = 9). Meta-analysis showed a non-significant per year of age decrease in added sugar or sucrose intake (-0.15% total energy intake (95%CI -0.41; 0.12)), a decrease in confectionery consumption (-0.20 servings/week (95%CI -0.41; -0.001)) and a non-significant decrease in SSB consumption (-0.15 servings/week (95%CI -0.32; 0.02)). Taken together, the overall decrease in added sugar intake observed from adolescence to early adulthood may suggest opportunities for intervention to further improve dietary choices within this age range. © 2017 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of World Obesity Federation.

  7. [Knowledge of Human Papillomavirus Infection and the Possibilities for Prevention among 13- to 21-Year-Old Students from Fulda, Hessen].

    Science.gov (United States)

    Stumm, C; Hahn, D; Heberlein, I; Doherr, F; Hofmann, W

    2017-05-01

    Study Aim: The aim of this investigation was to assess awareness and knowledge of HPV and HPV vaccination in a sample of female and male students from Fulda. Further vaccination uptake was investigated. Methods: In 2011 a regional cross-sectional survey of 13- to 21-year-old students (n=1 515) was conducted by using a standardised questionnaire. Results: Overall, the awareness and knowledge of human papillomavirus (HPV) was poor. 29% of the sample had heard of HPV. Multivariate analyses demonstrate that females as well as Christians knew HPV better than males and Muslims. Mean HPV knowledge score was 7.8 of 21 (SD=3.3). None of the tested sociodemographic variables was a predictor for better HPV knowledge. 77% of the sample was aware of the HPV vaccination. Females, persons without migration background as well as persons with middle or higher education knew HPV vaccination better than males, persons with migration background and lower educational level. Mean HPV vaccination knowledge score of the female students was 2.9 of 5 (SD=1.3). Older female students had a better level of knowledge than younger ones. 30% of the females had received at least one dose. Higher age, no migration background and middle or higher education status were tested as significant predictors of vaccine uptake. Conclusion: School lessons and consultations would be appropriate places to transfer knowledge in order to prevent health inequalities caused by social determinants. © Georg Thieme Verlag KG Stuttgart · New York.

  8. Peer victimization and subjective health among students reporting disability or chronic illness in 11 Western countries

    DEFF Research Database (Denmark)

    Sentenac, Mariane; Gavin, Aoife; Nic Gabhainn, Saoirse

    2013-01-01

    BACKGROUND: To compare the strength of the association between peer victimization at school and subjective health according to the disability or chronic illness (D/CI) status of students across countries. METHODS: This study used data from 55 030 students aged 11, 13 and 15 years from 11 countries...... reporting D/CI were more likely to report being victims of bullying. Victims of bullying reported more negative subjective health outcomes regardless of their D/CI status. Although inclusive education is currently a major topic of educational policies in most countries, additional efforts should be made...

  9. Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss Variants.

    Science.gov (United States)

    Krenciute, Giedre; Prinzing, Brooke L; Yi, Zhongzhen; Wu, Meng-Fen; Liu, Hao; Dotti, Gianpietro; Balyasnikova, Irina V; Gottschalk, Stephen

    2017-07-01

    Glioblastoma (GBM) is the most aggressive primary brain tumor in adults and is virtually incurable with conventional therapies. Immunotherapy with T cells expressing GBM-specific chimeric antigen receptors (CAR) is an attractive approach to improve outcomes. Although CAR T cells targeting GBM antigens, such as IL13 receptor subunit α2 (IL13Rα2), HER2, and EGFR variant III (EGFRvIII), have had antitumor activity in preclinical models, early-phase clinical testing has demonstrated limited antiglioma activity. Transgenic expression of IL15 is an appealing strategy to enhance CAR T-cell effector function. We tested this approach in our IL13Rα2-positive glioma model in which limited IL13Rα2-CAR T-cell persistence results in recurrence of antigen-positive gliomas. T cells were genetically modified with retroviral vectors encoding IL13Rα2-CARs or IL15 (IL13Rα2-CAR.IL15 T cells). IL13Rα2-CAR.IL15 T cells recognized glioma cells in an antigen-dependent fashion, had greater proliferative capacity, and produced more cytokines after repeated stimulations in comparison with IL13Rα2-CAR T cells. No autonomous IL13Rα2-CAR.IL15 T-cell proliferation was observed; however, IL15 expression increased IL13Rα2-CAR T-cell viability in the absence of exogenous cytokines or antigen. In vivo , IL13Rα2-CAR.IL15 T cells persisted longer and had greater antiglioma activity than IL13Rα2-CAR T cells, resulting in a survival advantage. Gliomas recurring after 40 days after T-cell injection had downregulated IL13Rα2 expression, indicating that antigen loss variants occur in the setting of improved T-cell persistence. Thus, CAR T cells for GBM should not only be genetically modified to improve their proliferation and persistence, but also to target multiple antigens. Summary: Glioblastoma responds imperfectly to immunotherapy. Transgenic expression of IL15 in T cells expressing CARs improved their proliferative capacity, persistence, and cytokine production. The emergence of antigen

  10. Correlates of Peer Violence Among 13- to 15-Year-Olds in Gampaha District Schools in Sri Lanka

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    Monika Priyadarshani Wijeratne

    2014-09-01

    Full Text Available Violence among adolescents in schools is a relatively new research area in South Asian countries. Limited knowledge about factors associated with peer violence hinders the design of prevention programs. This study was carried out to assess correlates of peer violence among 13- to 15-year-old adolescents in Gampaha district schools in Sri Lanka. A cross-sectional study was carried out to identify “violent” and “non-violent” adolescents. Study and control populations were identified based on their participatory roles in violence, and an unmatched case–control (1 case: 1 control analysis was carried out to assess correlates of peer violence. Bronfenbrenner’s ecological model was used, and correlates were determined for both physical and relational (verbal and non-verbal violence. Correlates of both physical and relational peer violence were male sex, being 13 years of age, mental health difficulties, dating relationships, school absenteeism, witnessing physical fights among neighbors, and crime-dense residence. Factors associated with peer violence operate at several levels: individual, family/peer relationships, community, and societal. Most of these factors are modifiable and can be targeted by prevention programs.

  11. Cognitive Functions in Elite and Sub-Elite Youth Soccer Players Aged 13 to 17 Years.

    Science.gov (United States)

    Huijgen, Barbara C H; Leemhuis, Sander; Kok, Niels M; Verburgh, Lot; Oosterlaan, Jaap; Elferink-Gemser, Marije T; Visscher, Chris

    2015-01-01

    Soccer players are required to anticipate and react continuously in a changing, relatively unpredictable situation in the field. Cognitive functions might be important to be successful in soccer. The current study investigated the relationship between cognitive functions and performance level in elite and sub-elite youth soccer players aged 13-17 years. A total of 47 elite youth soccer players (mean age 15.5 years, SD = 0.9) and 41 sub-elite youth soccer players (mean age 15.2 years, SD = 1.2) performed tasks for "higher-level" cognitive functions measuring working memory (i.e., Visual Memory Span), inhibitory control (i.e., Stop-Signal Task), cognitive flexibility (i.e., Trail Making Test), and metacognition (i.e., Delis-Kaplan Executive Function System Design Fluency Test). "Lower-level" cognitive processes, i.e., reaction time and visuo-perceptual abilities, were also measured with the previous tasks. ANOVA's showed that elite players outscored sub-elite players at the "higher-level" cognitive tasks only, especially on metacognition (p soccer players on inhibitory control (p = .001), and cognitive flexibility (p = .042), but not on metacognition (p = .27). No differences were found concerning working memory nor the "lower-level" cognitive processes (p > .05). In conclusion, elite youth soccer players have better inhibitory control, cognitive flexibility, and especially metacognition than their sub-elite counterparts. However, when training hours are taken into account, differences between elite and sub-elite youth soccer players remain apparent on inhibitory control and cognitive flexibility in contrast to metacognition. This highlights the need for longitudinal studies to further investigate the importance of "higher-level" cognitive functions for talent identification, talent development and performance in soccer.

  12. The Evaluation of Burnout Levels of Sports Sciences Faculty Students

    Science.gov (United States)

    Kocaeksi, Serdar

    2016-01-01

    The aim of this research is to evaluate the burnout levels of sports sciences faculty students in terms of some other variables. 46 Female (Age, M: 20.88 ± 1.86) and 107 male (Age, M: 22.15 ± 2.15) in total 153 students participated in this research. Maslach Burnout Inventory-Student Form (MBI-SF) was used for data collection. Descriptive…

  13. Nutritional knowledge and habits of adolescents aged 9 to 13 years in Sharjah, United Arab Emirates: a crosssectional study.

    Science.gov (United States)

    Al-Yateem, Nabeel; Rossiter, Rachel

    2017-10-30

    Good nutritional knowledge and behaviour among adolescents is important to avoid health problems that can continue into adulthood. This cross-sectional study aimed to provide baseline data on nutritional knowledge and eating habits of adolescents in Sharjah. Data were collected from 300 adolescents aged 9-13 years attending 4 private schools using a validated self-administered questionnaire. Most students (86%) had poor nutritional knowledge, especially in key areas: nutritional terms, what constitutes healthy snacks and foods, daily nutritional requirements and components of food (e.g. fibre, fat, sugar). Only 34% of the students had healthy eating behaviour: 33% had eaten none or 1 vegetable only in the previous week, 25% had eaten unhealthy snacks 3 or more times, 19% had eaten frequently or daily at fast food outlets, and 36% had skipped breakfast frequently or daily. Culturally-specific, school-based educational interventions are warranted to build sound nutritional knowledge among adolescents and motivate the diet and behaviour changes needed to promote health throughout the lifespan.

  14. Synthesis and biosynthesis of 13C, 15N labeled deoxynucleosides useful for biomolecular structural determinations

    International Nuclear Information System (INIS)

    Ashburn, D.A.; Garcia, K.; Hanners, J.L.; Silks, L.A. III; Unkefer, C.J.

    1994-01-01

    Currently, there is a great emphasis on elucidating the structure, function, and dynamics of DNA. Much of the research involved in this study utilizes nuclear magnetic resonance (NMR) spectroscopy. Effective use of NMR spectroscopy (more than 10,000 mw) in this arena requires stable isotope enrichment. Herein, the authors present strategies for the site-specific isotopic labeling of the purine bases adenosine and guanosine and the biosynthesis of [U- 13 C, 15 N] DNA from methylotrophic bacteria. With commercially available 6-chloropurine, an effective 2-step route leads to [6- 15 N]-2'-deoxadenosine (dA). The resulting [6- 15 N]-dA is used in a series of reactions to synthesize [2- 13 C, 1,2'- 15 N 2 ]-2'-deoxyguanosine or any combination thereof. An improved biosynthesis of labeled DNA has been accomplished using Methylobacterium extorquens AS1. Each liter of growth medium contains 4g of methanol to yield 1 gram of lyophilized cells. As much as 200 mg of RNA per liter of culture has been obtained. The authors are currently developing large scale isolation protocols. General synthetic pathways to oligomeric DNA are presented

  15. Synthesis and biosynthesis of 13C-, 15N-labeled deoxynucleosides useful for biomolecular structural determinations

    International Nuclear Information System (INIS)

    Ashburn, D.A.; Garcia, K.; Hanners, J.L.; Silks, L.A. III; Unkefer, C.J.

    1994-01-01

    Currently, there is a great emphasis on elucidating the structure, function, and dynamics of DNA. Much of the research involved in this study uses nuclear magnetic resonance (NMR) spectroscopy. Effective use of NMR spectroscopy for DNA molecules with mw > 10,000 requires stable isotope enrichment. We present strategies for site-specific isotopic labeling of the purine bases adenosine and guanosine and the biosynthesis of (U- 13 C, 15 N) DNA from methylotropic bacteria. With commercially available 6-chloropurine, an effective two-step route leads to 2'-deoxy-(amino- 15 N)adenosine (dA). The resulting d(amino- 15 N)A is used in a series of reactions to synthesize 2'-deoxy-(2- 13 C,1,amino- 15 N 2 )guanosine or any combination thereof. An improved biosynthesis of labeled DNA has been accomplished using Methylobacterium extorquens AS1. Each liter of growth medium contains 4 g of methanol to yield 1 g of lyophilized cells. As much as 200 mg of RNA per liter of culture has been obtained. We are currently developing large-scale isolation protocols. General synthetic pathways to oligomeric DNA will be presented

  16. Isolated Learners: Young Mature-Age Students, University Culture, and Desire for Academic Sociality

    Science.gov (United States)

    Mallman, Mark; Lee, Helen

    2017-01-01

    The differentiated experiences of "young" mature-age students are under-researched and often unacknowledged in higher education literature and university policy. This article contends that, due to their age (early 20s to early 30s), many younger mature-age students feel "out of the loop" and "alienated" from…

  17. Executive Functions as Predictors of School Performance and Social Relationships: Primary and Secondary School Students.

    Science.gov (United States)

    Zorza, Juan Pablo; Marino, Julián; Acosta Mesas, Alberto

    2016-05-12

    This study examined the relationship between executive functions (EFs) and school performance in primary and secondary school students aged 8 to 13 years (N = 146, M = 10.4, 45.8% girls). EFs were evaluated using the Trail Making Test (TMT), Verbal Fluency (VF), and the Stroop Test. Students' GPAs and teachers' assessment of academic skills were used to measure school performance. To evaluate the students' social behavior, participants were asked to rate all their classmates' prosocial behavior and nominate three students with whom they preferred to do school activities; teachers also provided evaluations of students' social skills. EF measures explained 41% (p = .003, f 2 = .694) of variability in school performance and 29% (p = .005, f 2 = .401) of variance in social behavior in primary school students. The predictive power of EFs was found to be lower for secondary school students, although the TMT showed significant prediction and explained 13% (p = .004, f 2 = .149) of variance in school performance and 15% (p = .008, f 2 = .176) in peer ratings of prosocial behavior. This paper discusses the relevance of EFs in the school environment and their different predictive power in primary and secondary school students.

  18. [Current situation of sleeping duration in Chinese Han students in 2010].

    Science.gov (United States)

    Song, Yi; Zhang, Bing; Hu, Peijin; Ma, Jun

    2014-07-01

    To analyze the characteristics of sleep duration in Chinese primary and middle school students. The data was collected from 30 provinces (Autonomous regions, Municipalities) in 165 363 Han Primary school students above 4 grade, the junior and senior high school students who participated in 2010 National Physical Fitness and Health Surveillance by using stratified random cluster sampling method, and the questionnaire of sleep duration, insufficient sleep and commuting way from school was conducted at the same time.χ² test and χ² linear-by-linear test were used to analyze the difference between the different groups, and logistic regression was used to analyze the factors of insufficient sleep. Nationwide in 2010, 39.09% (64 646/165 363) of students reported they had more than 8 hours sleep duration per day, the prevalence was lower among urban (37.06% (30 767/83 027)) than rural (41.15% (33 879/82 336)) students (χ² = 290.53, P sleep duration per day in 9-12 years group, 13-15 years group and 16-18 years group was 70.24% (43 934/62 549), 31.31% (16 166/51 652) and 8.89% (546/51 162), respectively, and decreased with the age increasing (χ² linear-by-linear = 50 617.75, P sleep was 93.64% (154 838/165 363) in total students, the prevalence was higher among urban (94.94% (78 829/83 027)) than rural students (92.32% (76 009/82 336)) (χ² = 479.14, P sleep in 9-12 years group, 13-15 years group and 16-18 years group was 96.42% (60 310/62 549), 92.76% (47 912/51 562) and 91.11% (46 616/51 162), respectively. A multivariate logistic regression analysis (OR (95% CI)) revealed that the insufficient sleep was significantly associated with being urban (1.58 (1.51-1.65)), being girls (1.39 (1.34-1.45)), being 9-12 years group (2.77 (2.62-2.93)), living in the middle (1.19 (1.13-1.25)) or western (1.08 (1.03-1.13)) of China, and commuting from school by bicycle (1.21 (1.14-1.28)), bus/car (1.09 (1.03-1.15)), or in a boarding school (1.17 (1.10-1.24)). The sleep duration

  19. Synthesis of specifically 15N- and 13C-labeled antitumor (2-Haloethyl)nitrosoureas. The study of their conformations in solution by nitrogen-15 and carbon-13 nuclear magnetic resonance and evidence for stereoelectronic control in their aqueous decomposition

    International Nuclear Information System (INIS)

    Lown, J.W.; Chauhan, S.M.S.

    1981-01-01

    The synthesis of certain specifically 15 N, 13 C, and 2 H isotope labeled 1-(2-chloroethyl)-3-alkyl-1-nitrosoureas (CENUs) is described. Spectroscopic examination of CENUs and their isotope-labeled counterparts by 1 H, 15 N, and 13 C NMR and infrared spectra indicates that they adopt preferred conformations in nonpolar aprotic solvents in which the NO group is aligned toward the 2-chloroethyl group. The result is in accord with the conformation of MeCCNU in the crystalline state derived from X-ray diffraction. The chemical shifts and coupling constants in the CENUs change with both solvent polarity and basicity. In aqueous phosphate buffer there is evidence for the formation of a tetrahedral intermediate, the conformation of which alters according to the reaction conditions and ultimately controls the formation of the aqueous decomposition products of CENUs. This is revealed most clearly by 13 C NMR of carbonyl- 13 C- and nitroso- 15 N-labeled BCNU and CCNU where two distinct 15 N-coupled 13 C doublets with different chemical shifts are observed. The rate of conformational change is comparable with the rate of decomposition of CENUs (via the second conformer) and may therefore represent the critical initial step of the latter process in vivo. The intermediacy of the postulated tetrahedral intermediates for CENUs is supported by observed 18 O exchange into the carbonyl group in 18 O-enriched water. Consideration of the conformations of the intermediates and of the alignment of the heteroatom lone pairs provides a satisfactory interpretation of the reactions of CENUs in aqueous solution as well as their pH dependence in terms of strict steroelectronic control and accounts for the formation of the observed products

  20. Progress in 15N and 13C separation by isotopic exchange

    International Nuclear Information System (INIS)

    Axente, D.

    2004-01-01

    An experimental study of 15 N separation by isotopic exchange in NO, NO 2 - HNO 3 system under pressure is presented. The pressure increase in 15 N separation plant improved the isotopic transport between the two phases circulated in counter-current in the packed column according to a better kinetics of isotopic exchange at higher pressures. The operation of 15 N separation plant at a pressure of 1.8 atm (absolute) will permit doubling of 10 M nitric acid flow rate and of 15 N production of a given column. The improved performance at a higher pressure is significant for large scale 15 N production, which would be utilized for uranium nitride fuels for FBRs. Enrichment of 13 C by chemical exchange between CO 2 and amine carbamate in nonaqueous solvent has been modelled. For process optimization the steady state separation and the height equivalent to a theoretical plate (HETP) have been determined for different experimental conditions and simulated for higher pressures than atmospheric one. At lower temperature (5 deg C) as the pressure increases the quantity of CO 2 dissolved in amine solution increases. For process analysis at higher pressures and lower temperatures, the two steps model has been considered. At 0.9 MPa pressure and 5 deg C the reaction rate is higher than at 25 deg C and atmospheric pressure, the value of HETP being lower with more than 100% than at 25 deg C. (author)

  1. A Mouse Model that Recapitulates Cardinal Features of the 15q13.3 Microdeletion Syndrome Including Schizophrenia- and Epilepsy-Related Alterations

    DEFF Research Database (Denmark)

    Fejgin, Kim; Nielsen, Jacob; Birknow, Michelle R.

    2014-01-01

    to develop myoclonic and absence-like seizures but decreased propensity for clonic and tonic seizures. Furthermore, they had impaired long-term spatial reference memory and a decreased theta frequency in hippocampus and prefrontal cortex. Electroencephalogram characterization revealed auditory processing......Background: Genome-wide scans have uncovered rare copy number variants conferring high risk of psychiatric disorders. The 15q13.3 microdeletion is associated with a considerably increased risk of idiopathic generalized epilepsy, intellectual disability, and schizophrenia. Methods: A 15q13.......3 microdeletion mouse model (Df[h15q13]/) was generated by hemizygous deletion of the orthologous region and characterized with focus on schizophrenia- and epilepsy-relevant parameters. Results: Df(h15q13)/ mice showed marked changes in neuronal excitability in acute seizure assays, with increased propensity...

  2. Analysis of nitrate absorption and transport in non-nodulated and nodulated soybean plants with 13NO3- and 15NO3-

    International Nuclear Information System (INIS)

    Sato, Takashi; Ohtake, Norikuni; Ohyama, Takuji

    1999-01-01

    Nodulating (T202) and non-nodulating (T201) soybean isolines were hydroponically cultivated, then nitrate labeled with 13 N or 15 N, was added to the culture solution in order to investigate the nitrate absorption and transport in soybean. The accumulation pattern of the absorbed 13 N in the first trifoliate was observed by positron emitting tracer imaging system (PETIS) as well as bioimaging analyzer system (BAS). The 15 N abundance of each part was determined by emission spectrometry. Real time changes in two dimensional image of the radioactivity could be monitored by PETIS, besides the distribution 13 N in whole plant could be observed by BAS. However quantitative data were hardly obtained by the 13 N analysis. Stable isotope 15 N is more reliable in the quantitative analysis in each part. Combing the data obtained by 15 N and 13 N tracer experiments, the absorption and translocation of N in plant should be more clearly figured out. (author)

  3. Male Eating Disorder Symptom Patterns and Health Correlates From 13 to 26 Years of Age

    Science.gov (United States)

    Calzo, Jerel P.; Horton, Nicholas J.; Sonneville, Kendrin R.; Swanson, Sonja; Crosby, Ross D.; Micali, Nadia; Eddy, Kamryn T.; Field, Alison E.

    2016-01-01

    Objective Research on the manifestations and health correlates of eating disorder symptoms among males is lacking. This study identified patterns of appearance concerns and eating disorder behaviors from adolescence through young adulthood and their health correlates. Method Participants were 7,067 males from the prospective Growing Up Today Study. Surveys from 1999–2007 (spanning ages 13–26 years) provided repeated measures data on: muscularity and leanness concerns; eating disorder behaviors (purging, overeating, binge eating, use of muscle-building products); and health correlates (obesity, non-marijuana drug use, binge drinking, and depressive symptoms). Results Latent class analyses of observations at ages 1315, 16–18, 19–22, and 23–26 identified one large Asymptomatic class and four symptomatic patterns: Body Image Disturbance (high appearance concerns, low eating disorder behaviors; 1.0%–6.0% per age period); Binge Eating/Purging (binge eating and purging, use of muscle-building products, low appearance concerns; 0.1%–2.5%); Mostly Asymptomatic (low levels of muscularity concern, product use, and overeating; 3.5%–5.0%); and Muscularity Concerns (high muscularity concerns and use of products; 0.6%–1.0%). The Body Image Disturbance class was associated with high estimated prevalence of depressive symptoms. Males in the Binge Eating/Purging and Muscularity Concerns classes had high prevalence of binge drinking and drug use. Despite exhibiting modestly greater appearance concerns and eating disorder behaviors than the Asymptomatic class, being in the Mostly Asymptomatic class was prospectively associated with adverse health outcomes. Conclusion Results underscore the importance of measuring concerns about leanness, muscularity, and use of muscle-building products when assessing eating disorder presentations among males in research and clinical settings. PMID:27453083

  4. Antecedents of Suicide among Youth Aged 11-15: A Multistate Mixed Methods Analysis.

    Science.gov (United States)

    Holland, Kristin M; Vivolo-Kantor, Alana M; Logan, Joseph E; Leemis, Ruth W

    2017-07-01

    Suicide is the second leading cause of death for youth aged 11 to 15, taking over 5,500 lives from 2003 to 2014. Suicide among this age group is linked to risk factors such as mental health problems, family history of suicidal behavior, biological factors, family problems, and peer victimization and bullying. However, few studies have examined the frequency with which such problems occur among youth suicide decedents or the context in which decedents experience these risk factors and the complex interplay of risk that results in a decedent's decision to take his/her own life. Data from a random sample of 482 youth (ages 11-15) suicide cases captured in the National Violent Death Reporting System from 2003 to 2014 were analyzed. The sample had fewer girls than boys (31 vs. 69 %) and comprised primarily White youth (79 %), but also African Americans (13 %), Asians (4 %), and youth of other races (4 %). Narrative data from coroner/medical examiner and law enforcement investigative reports were coded and analyzed to identify common behavioral patterns that preceded suicide. Emergent themes were quantified and examined using content and constant comparative analysis. Themes regarding antecedents across multiple levels of the social ecology emerged. Relationship problems, particularly with parents, were the most common suicide antecedent. Also, a pattern demonstrating a consistent progression toward suicidal behavior emerged from the data. Narratives indicated that youth were commonly exposed to one or more problems, often resulting in feelings of loneliness and burdensomeness, which progressed toward thoughts and sometimes plans for or attempts at suicide. Continued exposure to negative experiences and thoughts/plans about suicide, and/or self-injurious acts resulted in an acquired capacity to self-harm, eventually leading to suicide. These findings provide support for theories of suicidal behavior and highlight the importance of multi-level, comprehensive

  5. EATING HABITS: A study with adolescents aged 10 to 15, from Gaspar Bartholomay Elementary School in Santa Cruz do Sul

    Directory of Open Access Journals (Sweden)

    Bruna Fernada Soder

    2012-11-01

    Full Text Available Eating habits in adolescence, may suffer several changes as they can vary from one day to another. The objective of this study is to determine the eating habits of adolescents aged 10 to 15 years old. The study comprised 81 students aged between 10 and 15 years, 48 male and 33 female students, from Gaspar Bartholomay Elementary School. The research was carried out through a descriptive exploratory study, addressing the eating habits and weight control, and focusing on the frequency of food consumption per week. The tool for the study was a questionnaire on health and well-being - children and adolescents - eating habits and weight control. According to the results obtained in this study, the consumption of fried foods, pizza, lasagna and treats,were consumed less frequently, being considered among adolescents as a good eating habit, since foods such as these will cause obesity if consumed more frequently and in large quantities. In relation to the consumption of salads and vegetables males (40.5% have the habit of eating more that kind of food, when compared to the females(38.2%. For both genders, adults become more or less prone to obesitywith a more regular consumption of this type of food. Thus, we can see that the teenagers in their diet, prioritize foods they like to eat, and seldom choose foods which are healthier, without worrying about becoming obese adolescents or even in the future, obese adults with poor eating habits.

  6. RESEARCH OF THE METABOLIC AGE AND BODY MASS INDEX FOR FEMALE STUDENTS

    Directory of Open Access Journals (Sweden)

    Galina Petrova Dyakova

    2011-09-01

    Full Text Available Metabolic age - this feature takes into account, the basic metabolism and all the basic physical parameters and the determining of age, which corresponds to this type of metabolism. The aim of the research is to establish a metabolic age and the index of the body mass (Body Mass Index for students. Anthropometric measurement was applied. The analyzer was used for the composition of body weight (body composition analyzer, BC-420MA “Tanita” for determining the metabolic age and body mass index. The conducted monitoring of the metabolic age reveals opportunities to improve students' motivation for healthy lifestyle.

  7. Summer Students

    CERN Multimedia

    2005-01-01

    SUMMER STUDENT LECTURE PROGRAMME Main Auditorium, bldg. 500 DATE TIME LECTURER TITLE Wednesday 6 July 09:15 - 10:00 F. CERUTTI (CERN) Presentation of the Summer Student Programme D. Heagerty (CERN) Computer rules O. ULLALAND (CERN) Workshops presentation 10:15 - 11:00 D. SCHLATTER (CERN) Introduction to CERN 11:15 Film on CERN Thursday 7 July 09:15 - 11:00 L. Di Lella (CERN) Introduction to Particle Physics (1-2/4) 11:15 - 12:00 P. Chomaz (GANIL / CERN) Introduction to Nuclear Physics (1/3) 12:00 Discussion Session 14:00 - 14:45 M. Lindroos (CERN) ISOLDE Facility 15:00 M. Lindroos (CERN) ISOLDE Visit Friday 8 July 09:15 - 10:00 L. Di Lella (CERN) Introduction to Particle Physics (3/4) 10:15 - 11:00 P. Chomaz (GANIL / CERN) Introduction to Nuclear Physics (2/3) 11:15 - 12:00 G. ROLANDI (CERN) How an experiment is designed (1/2) 12:00 Discussion Session Monday 11 July 09:15 - 10:00 L. Di Lella (CERN) Introduction to Particle Physi...

  8. Encountering aged care: a mixed methods investigation of medical students' clinical placement experiences.

    Science.gov (United States)

    Annear, Michael J; Lea, Emma; Lo, Amanda; Tierney, Laura; Robinson, Andrew

    2016-02-04

    Residential aged care is an increasingly important health setting due to population ageing and the increase in age-related conditions, such as dementia. However, medical education has limited engagement with this fast-growing sector and undergraduate training remains primarily focussed on acute presentations in hospital settings. Additionally, concerns have been raised about the adequacy of dementia-related content in undergraduate medical curricula, while research has found mixed attitudes among students towards the care of older people. This study explores how medical students engage with the learning experiences accessible in clinical placements in residential aged care facilities (RACFs), particularly exposure to multiple comorbidity, cognitive impairment, and palliative care. Fifth-year medical students (N = 61) completed five-day clinical placements at two Australian aged care facilities in 2013 and 2014. The placements were supported by an iterative yet structured program and academic teaching staff to ensure appropriate educational experiences and oversight. Mixed methods data were collected before and after the clinical placement. Quantitative data included surveys of dementia knowledge and questions about attitudes to the aged care sector and working with older adults. Qualitative data were collected from focus group discussions concerning medical student expectations, learning opportunities, and challenges to engagement. Pre-placement surveys identified good dementia knowledge, but poor attitudes towards aged care and older adults. Negative placement experiences were associated with a struggle to discern case complexity and a perception of an aged care placement as an opportunity cost associated with reduced hospital training time. Irrespective of negative sentiment, post-placement survey data showed significant improvements in attitudes to working with older people and dementia knowledge. Positive student experiences were explained by in

  9. 15-Deoxy-Δ{sup 12,14}-prostaglandin J{sub 2} inhibits IL-13 production in T cells via an NF-κB-dependent mechanism

    Energy Technology Data Exchange (ETDEWEB)

    Doyle, Marie-Christine; Tremblay, Sarah [Département de Biologie, Faculté des Sciences, Université de Sherbrooke, Sherbrooke (QC), Canada J1K 2R1 (Canada); Dumais, Nancy, E-mail: nancy.dumais@usherbrooke.ca [Département de Biologie, Faculté des Sciences, Université de Sherbrooke, Sherbrooke (QC), Canada J1K 2R1 (Canada)

    2013-02-15

    Highlights: ► 15d-PGJ{sub 2} decreased IL-13 mRNA transcription and secretion in activated T cells. ► IL-13 inhibition by 15d-PGJ{sub 2} is independent of PPAR-γ. ► The nuclear factor-κB mediates the 15d-PGJ{sub 2}-dependent down regulation of IL-13. -- Abstract: Interleukin (IL)-13 is a cytokine produced by activated CD4{sup +} T cells that plays a critical role in promoting allergic responses and tumor cell growth. The 15-deoxy-Δ{sup 12,14}-prostaglandin J{sub 2} (15d-PGJ{sub 2}) is a natural ligand for the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-γ), a known regulator of anti-inflammatory activities. We determined the effects of 15d-PGJ{sub 2} on IL-13 expression in the Jurkat E6.1 T-cell line and in peripheral blood mononuclear cells. Semi-quantitative reverse transcription-polymerase chain reaction and enzyme-linked immunosorbent assay revealed that treatment of activated T cells with 15d-PGJ{sub 2} significantly decreased IL-13 mRNA transcription and secretion, respectively. This inhibition by 15d-PGJ{sub 2} was independent of PPAR-γ since treatment with GW9662, an irreversible antagonist of the nuclear receptor, produced no effect. Our data also revealed the involvement of nuclear factor-κB in mediating 15d-PGJ{sub 2}-dependent down regulation of IL-13 expression. Collectively, these results demonstrate the potential of 15d-PGJ{sub 2} in attenuating expression and production of IL-13 in activated T cells.

  10. Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice

    OpenAIRE

    Zhang, Wenliang; Zhong, Wei; Sun, Qian; Sun, Xinguo; Zhou, Zhanxiang

    2017-01-01

    Chronic alcohol feeding causes lipid accumulation and apoptosis in the liver. This study investigated the role of bioactive lipid metabolites in alcohol-induced liver damage and tested the potential of targeting arachidonate 15-lipoxygenase (ALOX15) in treating alcoholic liver disease (ALD). Results showed that chronic alcohol exposure induced hepatocyte apoptosis in association with increased hepatic 13-HODE. Exposure of 13-HODE to Hepa-1c1c7 cells induced oxidative stress, ER stress and apo...

  11. Affordable uniform isotope labeling with 2H, 13C and 15N in insect cells

    International Nuclear Information System (INIS)

    Sitarska, Agnieszka; Skora, Lukasz; Klopp, Julia; Roest, Susan; Fernández, César; Shrestha, Binesh; Gossert, Alvar D.

    2015-01-01

    For a wide range of proteins of high interest, the major obstacle for NMR studies is the lack of an affordable eukaryotic expression system for isotope labeling. Here, a simple and affordable protocol is presented to produce uniform labeled proteins in the most prevalent eukaryotic expression system for structural biology, namely Spodoptera frugiperda insect cells. Incorporation levels of 80 % can be achieved for 15 N and 13 C with yields comparable to expression in full media. For 2 H, 15 N and 2 H, 13 C, 15 N labeling, incorporation is only slightly lower with 75 and 73 %, respectively, and yields are typically twofold reduced. The media were optimized for isotope incorporation, reproducibility, simplicity and cost. High isotope incorporation levels for all labeling patterns are achieved by using labeled algal amino acid extracts and exploiting well-known biochemical pathways. The final formulation consists of just five commercially available components, at costs 12-fold lower than labeling media from vendors. The approach was applied to several cytosolic and secreted target proteins

  12. The Halitosis Parameter Change After Using Siwak (Salvadora Persica At 11-13 Year Old Students in Tapak Sunan Boarding School

    Directory of Open Access Journals (Sweden)

    Arum Wijayanti

    2012-12-01

    Full Text Available Introduction: Siwak (Salvadora persica, an oral cleansing tool which came from ancient Arab has Islamic cultural values. Many researches concluded that siwak contains antibacterial agent which has function to kill bacteria causing oral malodor (halitosis. Objective: The purpose of this study was to analyze halitosis parameters change which consisted of Volatile Sulfur Compounds (VSC, Bleeding on Probing (BOP and tongue coating after using siwak at 11-13 year old students in Tapak Sunan Boarding School. Materials and methods: This study used experimental research method and 25 students in the age group of 11-13 year old became subjects of this study. Halitosis parameters measurements were taken before and after using 10 days siwak usage and through dental health education. OralChroma and organoleptic score were used to measure the VSC. Probing on six sites of gingival sulculs of each tooth was used to measured BOP. Classification of tounge coating was performed by observing the presence of white coating on the tongue surface. Statistical analysis was performed using Paired-t Test with p<0.05 as the level of significance. Results: Approximately 75% reduction of total VSC concentration was observed after siwak usage. Number of subjects with score 1 in organoleptic assessment for halitosis was also increased by 36%. Followed by reduction of BOP and tongue coating score by 57.7% and 26% respectively. Statistical analysis of those parameters showed significant differences before and after siwak usage. Conclusion: Siwak usage sucessfully decreased all halitosis parameters of the 11-13 years old students in Tapak Sunan Boarding School.DOI: 10.14693/jdi.v17i2.45

  13. The Interplay of Students' School Engagement, School Self-Concept and Motivational Relations during Adolescence.

    Science.gov (United States)

    Bakadorova, Olga; Raufelder, Diana

    2017-01-01

    Existing literature evidences the association between adolescents' school self-concept and engagement, both concepts being related to students' perception of teachers and peers as motivators. However, few longitudinal studies explore the interplay of these factors. The present study aims to close this gap, applying latent cross-lagged panel design to two-wave data from German adolescent students [1088 8th grade students at T1 ( M age = 13.7, SD = 0.53; 53.9% girls) and 845 9th grade students at T2 ( M age = 14.86; SD = 0.57; 55% girls) from the initial sample]. Besides direct effects, three cross-lagged over-time paths were found to be significant: students' perception of peers as positive motivators (PPMs) at the beginning of 8th grade (T1) positively predicts their behavioral school engagement at the end of 9th grade (T2), as well as emotional school engagement at the beginning of 8th grade positively predicts students' perception of PPMs 1.5 years later. Furthermore, behavioral school engagement at T1 functions as a predictor of a student's school self-concept at T2.

  14. Age determination of 15 old to intermediate-age small Magellanic cloud star clusters

    International Nuclear Information System (INIS)

    Parisi, M. C.; Clariá, J. J.; Piatti, A. E.; Geisler, D.; Leiton, R.; Carraro, G.; Costa, E.; Grocholski, A. J.; Sarajedini, A.

    2014-01-01

    We present color-magnitude diagrams in the V and I bands for 15 star clusters in the Small Magellanic Cloud (SMC) based on data taken with the Very Large Telescope (VLT, Chile). We selected these clusters from our previous work, wherein we derived cluster radial velocities and metallicities from calcium II infrared triplet (CaT) spectra also taken with the VLT. We discovered that the ages of six of our clusters have been appreciably underestimated by previous studies, which used comparatively small telescopes, graphically illustrating the need for large apertures to obtain reliable ages of old and intermediate-age SMC star clusters. In particular, three of these clusters, L4, L6, and L110, turn out to be among the oldest SMC clusters known, with ages of 7.9 ± 1.1, 8.7 ± 1.2, and 7.6 ± 1.0 Gyr, respectively, helping to fill a possible 'SMC cluster age gap'. Using the current ages and metallicities from Parisi et al., we analyze the age distribution, age gradient, and age-metallicity relation (AMR) of a sample of SMC clusters measured homogeneously. There is a suggestion of bimodality in the age distribution but it does not show a constant slope for the first 4 Gyr, and we find no evidence for an age gradient. Due to the improved ages of our cluster sample, we find that our AMR is now better represented in the intermediate/old period than we had derived in Parisi et al., where we simply took ages available in the literature. Additionally, clusters younger than ∼4 Gyr now show better agreement with the bursting model of Pagel and Tautvaišienė, but we confirm that this model is not a good representation of the AMR during the intermediate/old period. A more complicated model is needed to explain the SMC chemical evolution in that period.

  15. Trends in overweight prevalence among 11-, 13- and 15-year-olds in 25 countries in Europe, Canada and USA from 2002 to 2010

    DEFF Research Database (Denmark)

    Ahluwalia, Namanjeet; Dalmasso, Paola; Rasmussen, Mette

    2015-01-01

    BACKGROUND: The purpose of this study was to assess recent changes in the prevalence of overweight (including obesity) among 11-, 13- and 15-year-olds in 33 countries from 2002 to 2010. METHODS: Data from 25 countries from three consecutive survey cycles (2002, 2006 and 2010) that had at least 80...... and highlight the need to understand cross-national differences by examining macro-level indicators. Such research should feed into developing sound translations and practices to prevent and reduce overweight in youth.......% response rate for self-reported height, weight and age were analysed using logistic regression analysis. RESULTS: Overweight prevalence increased among boys in 13 countries and among girls in 12 countries; in 10 countries, predominantly in Eastern Europe, an increase was observed for both boys and girls...

  16. Chemienzymatic synthesis of Uridine. Nucleotides labeled with [15N] and [13C

    DEFF Research Database (Denmark)

    Gilles, Anne-Marie; Cristea, Ioan; Palibroda, Nicolae

    1995-01-01

    +necessary for the oxidation of glucose 6-phosphate and 6-phosphogluconate was recycled by glutamate dehydrogenase and excess of ammonia and a-oxoglutarate. Despite the number and complexity of the enzymatic steps, the synthesis of [15N,13C]UTP is straightforward with an overall yield exceeding 60%. This method, extended...... and diversified to the synthesis of all natural ribonucleotides, is a more economical alternative for obtaining nucleic acids for structural analysis by heteronuclear NMR spectroscopy....

  17. Evaluation of Some Physical Fitness Characteristics in 11-13 Years Old

    Science.gov (United States)

    Popovici, Ileana Monica; Popescu, Lucian; Radu, Liliana-Elisabeta

    2017-01-01

    Many studies indicate that a physical fitness characteristic is an important marker for healthy body and healthy mind. The major purpose of this study is to explore the levels of physical fitness of the students between 11 and 13 years of age. The participants of this study are 251 volunteer students including 95 boys and 156 girls between the…

  18. Alteration of /sup 15/N//sup 14/N and /sup 13/C//sup 12/C ratios of plant matter during the initial stages of diagenesis: studies utilizing archaeological specimens from Peru

    Energy Technology Data Exchange (ETDEWEB)

    DeNiro, M J [California Univ., Los Angeles (USA). Dept. of Earth and Space Sciences; Hastorf, C A [California Univ., Los Angeles (USA). Dept. of Anthropology

    1985-01-01

    The stable carbon and nitrogen isotope ratios of plants extracted from Peruvian archaeological sites, ranging in age from 400 to 4000 years B.P., have been measured. The delta/sup 13/C and delta/sup 15/N values of prehistoric plants that were carbonized prior to deposition are similar to those of modern plants which have the same carbon dioxide fixation or nitrogen assimilation mechanisms. In contrast, the delta/sup 15/N values of prehistoric plants that were not carbonized are generally 10 to 20 per mille and as much as 35 per mille more positive than those of their modern counterparts. The delta/sup 13/C and delta/sup 15/N values of different parts of prehistoric uncarbonized plants differ by as much as 8 per mille and 21 per mille respectively, whereas the same parts of modern plants have delta/sup 13/C or delta/sup 15/N values that lie within 2 per mille of one another. SEM analysis eliminated the possibility that diagenetic alteration of the isotope ratios of the prehistoric uncarbonized plants was caused by the adsorption of particulate soil matter. The results are discussed.

  19. Medical and Psychology Students' Knowledge and Attitudes regarding Aging and Sexuality

    Science.gov (United States)

    Snyder, Rachel J.; Zweig, Richard A.

    2010-01-01

    The current study surveys medical and doctoral psychology students (N = 100) from an urban northeastern university regarding knowledge and attitudes toward elderly sexuality and aging using the Facts on Aging Quiz, the Aging Sexuality Knowledge and Attitudes Scale, and measures of interest in gerontology, academic/clinical exposure to aging and…

  20. Tetrasomy 15q11-q13 Diagnosed by FISH in a Patient with Autistic Disorder

    Directory of Open Access Journals (Sweden)

    Karim Ouldim

    2007-01-01

    Full Text Available We report the case of a Moroccan boy with mental retardation, hyperactivity, epilepsy, developmental problems and behavioural disorders. Cytogenetic analysis showed the presence of a supernumerary marker chromosome. Molecular cytogenetics allowed us to determine the marker as an inverted duplication of chromosome 15. It is the first case of a Moroccan patient with tetrasomy 15q in which fluorescence in situ hybridization (FISH enabled us to specify the diagnosis. Interestingly, this patient has an infantile autism with cytogenetic abnormalities on chromosomal region 15q11-q13 as reported in patients with Autistic Disorder.

  1. Espiritu Santo, Vanuatu Stable Isotope (delta 18O, delta 13C) Data for 1806 to 1979

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Site: Espiritu Santo Island, Vanuatu, 15S, 167E. 173 year record of d18O and d13C. Variable names: QSR Age, QSR 13C, QSR 18O, GRL Age, GRL Qtrly 13C, GRL Qtrly 18O,...

  2. [1-13C]Glucose entry in neuronal and astrocytic intermediary metabolism of aged rats. A study of the effects of nicergoline treatment by 13C NMR spectroscopy.

    Science.gov (United States)

    Miccheli, Alfredo; Puccetti, Caterina; Capuani, Giorgio; Di Cocco, Maria Enrica; Giardino, Luciana; Calzà, Laura; Battaglia, Angelo; Battistin, Leontino; Conti, Filippo

    2003-03-14

    Age-related changes in glucose utilization through the TCA cycle were studied using [1-13C]glucose and 13C, 1H NMR spectroscopy on rat brain extracts. Significant increases in lactate levels, as well as in creatine/phosphocreatine ratios (Cr/PCr), and a decrease in N-acetyl-aspartate (NAA) and aspartate levels were observed in aged rat brains as compared to adult animals following glucose administration. The total amount of 13C from [1-13C]glucose incorporated in glutamate, glutamine, aspartate and GABA was significantly decreased in control aged rat brains as compared to adult brains. The results showed a decrease in oxidative glucose utilization of control aged rat brains. The long-term nicergoline treatment increased NAA and glutamate levels, and decreased the lactate levels as well as the Cr/PCr ratios in aged rat brains as compared to adult rats. The total amount of 13C incorporated in glutamate, glutamine, aspartate, NAA and GABA was increased by nicergoline treatment, showing an improvement in oxidative glucose metabolism in aged brains. A significant increase in pyruvate carboxylase/pyruvate dehydrogenase activity (PC/PDH) in the synthesis of glutamate in nicergoline-treated aged rats is consistent with an increase in the transport of glutamine from glia to neurons for conversion into glutamate. In adult rat brains, no effect of nicergoline on glutamate PC/PDH activity was observed, although an increase in PC/PDH activity in glutamine was, suggesting that nicergoline affects the glutamate/glutamine cycle between neurons and glia in different ways depending on the age of animals. These results provide new insights into the effects of nicergoline on the CNS.

  3. Adherence to the Mediterranean Diet and Factors Affecting Obesity in High School Students

    Directory of Open Access Journals (Sweden)

    Aysun Yüksel

    2017-12-01

    Full Text Available The prevalence overweight and obese among children and adolescents increases gradually in the world and became an epidemic in both developing and developed countries. Overweight and obesity in the adolescent period are the main risk factors contributing to the development of cardiovascular diseases in the adulthood period. This study was planned to reveal the prevalence of obesity and association of healthy lifestyle behaviors with obesity in adolescents. Methods: This research was carried out 859 students studying at Istanbul Hezarfen High School between the dates 1 February to 31 March 2017. The general dietary habits and night eating statuses were determined using the Mediterranean Diet Quality Index (KIDMED and Night Eating Questionnaire (NEQ and anthropometric parameters such as height and body weight were measured. Results: The mean age of the students was 15.9 ± 1.3 years. Of the students, 19.2% had overweight, 13.7% had obese BMI values. In this study, 32.4% of all students had low and 13% of them had optimal nutritional quality. The difference between two genders was statistically significant (p<0.05. The Night Eating Syndrome was not present in 78.9% of all students whereas it was detected in 21.1% of them. Conclusions: In our study, there was no statistically significant relationship between obesity, adherence to Mediterranean Diet and Night Eating Syndrome.

  4. Probiotic and anti-inflammatory potential of Lactobacillus rhamnosus 4B15 and Lactobacillus gasseri 4M13 isolated from infant feces.

    Science.gov (United States)

    Oh, Nam Su; Joung, Jae Yeon; Lee, Ji Young; Kim, Younghoon

    2018-01-01

    A total of 22 Lactobacillus strains, which were isolated from infant feces were evaluated for their probiotic potential along with resistance to low pH and bile salts. Eight isolates (L. reuteri 3M02 and 3M03, L. gasseri 4M13, 4R22, 5R01, 5R02, and 5R13, and L. rhamnosus 4B15) with high tolerance to acid and bile salts, and ability to adhere to the intestine were screened from 22 strains. Further, functional properties of 8 Lactobacillus strains, such as anti-oxidation, inhibition of α-glucosidase activity, cholesterol-lowering, and anti-inflammation were evaluated. The properties were strain-specific. Particularly, two strains of L. rhamnosus, 4B15 (4B15) and L. gasseri 4M13 (4M13) showed considerably higher anti-oxidation, inhibition of α-glucosidase activity, and cholesterol-lowering, and greater inhibition of nitric oxide production than other strains. Moreover, the two selected strains substantially inhibited the release of inflammatory mediators such as TNF-α, IL-6, IL-1β, and IL-10 stimulated the treatment of RAW 264.7 macrophages with LPS. In addition, whole genome sequencing and comparative genomic analysis of 4B15 and 4M13 indicated them as novel genomic strains. These results suggested that 4B15 and 4M13 showed the highest probiotic potential and have an impact on immune health by modulating pro-inflammatory cytokines.

  5. Probiotic and anti-inflammatory potential of Lactobacillus rhamnosus 4B15 and Lactobacillus gasseri 4M13 isolated from infant feces.

    Directory of Open Access Journals (Sweden)

    Nam Su Oh

    Full Text Available A total of 22 Lactobacillus strains, which were isolated from infant feces were evaluated for their probiotic potential along with resistance to low pH and bile salts. Eight isolates (L. reuteri 3M02 and 3M03, L. gasseri 4M13, 4R22, 5R01, 5R02, and 5R13, and L. rhamnosus 4B15 with high tolerance to acid and bile salts, and ability to adhere to the intestine were screened from 22 strains. Further, functional properties of 8 Lactobacillus strains, such as anti-oxidation, inhibition of α-glucosidase activity, cholesterol-lowering, and anti-inflammation were evaluated. The properties were strain-specific. Particularly, two strains of L. rhamnosus, 4B15 (4B15 and L. gasseri 4M13 (4M13 showed considerably higher anti-oxidation, inhibition of α-glucosidase activity, and cholesterol-lowering, and greater inhibition of nitric oxide production than other strains. Moreover, the two selected strains substantially inhibited the release of inflammatory mediators such as TNF-α, IL-6, IL-1β, and IL-10 stimulated the treatment of RAW 264.7 macrophages with LPS. In addition, whole genome sequencing and comparative genomic analysis of 4B15 and 4M13 indicated them as novel genomic strains. These results suggested that 4B15 and 4M13 showed the highest probiotic potential and have an impact on immune health by modulating pro-inflammatory cytokines.

  6. Comparison of 15N- and 13C-determined parameters of mobility in melittin

    International Nuclear Information System (INIS)

    Zhu Lingyang; Prendergast, Franklyn G.; Kemple, Marvin D.

    1998-01-01

    Backbone and tryptophan side-chain mobilities in the 26-residue, cytolytic peptide melittin (MLT) were investigated by 15 N and 13 C NMR. Specifically, inverse-detected 15 N T 1 and steady-state NOE measurements were made at 30 and 51 MHz on MLT at 22 deg. C enriched with 15 N at six amide positions and in the Trp 19 side chain. Both the disordered MLT monomer (1.2 mM peptide at pH 3.6 in neat water) and α-helical MLT tetramer (4.0 mM peptide at pH 5.2 in 150 mM phosphate buffer) were examined. The relaxation data were analyzed in terms of the Lipari and Szabo model-free formalism with three parameters: τ m , the correlation time for the overall rotation; S 2 , a site-specific order parameter which is a measure of the amplitude of the internal motion; and τ e , a local, effective correlation time of the internal motion. A comparison was made of motional parameters from the 15 N measurements and from 13 C measurements on MLT, the latter having been made here and previously [Kemple et al. (1997) Biochemistry, 36, 1678-1688]. τ m and τ e values were consistent from data on the two nuclei. In the MLT monomer, S 2 values for the backbone N-H and Cα-H vectors in the same residue were similar in value but in the tetramer the N-H order parameters were about 0.2 units larger than the Cα-H order parameters. The Trp side-chain N-H and C-H order parameters, and τ e values were generally similar in both the monomer and tetramer. Implications of these results regarding the dynamics of MLT are examined

  7. A Comparative Study of Undergraduates' Attitudes Toward Aging in Taiwan and the United States Through Student Drawings.

    Science.gov (United States)

    Liou, Chih-Ling

    2017-09-01

    The purpose of this study is to compare similarities and differences in the attitudes toward aging among college students from Taiwan and the United States; 128 Taiwanese students and 124 U.S. students participated in this study. The findings indicate that the majority of students from both countries viewed aging as consisting primarily of physical changes. The differences are the U.S. students' drawings showing physical decline along with hospitals, nursing homes, or death, whereas Taiwanese students presenting physical decline as getting wrinkles, wearing glasses, or needing aid devices. U.S. students associated aging with grandparents-grandchildren relationships, whereas more Taiwanese students thought aging related to spousal relationships. This study adds to the existing literature that demonstrates the strong influence of different cultures on students' attitudes toward aging. Further, knowledge derived from this study can be used in gerontology courses for both students and professors to lessen or correct ageist stereotypes over time.

  8. 13C- and 15N-labelled non-biogenic compounds used as stable isotope drugs for human liver function tests

    International Nuclear Information System (INIS)

    Krumbiegel, P.

    1989-01-01

    As a result of liver diseases, the elimination of certain drugs is retarded. After labelling a suitable drug with 13 C, the 13 CO 2 elimination rate serves as a liver function parameter. Current contributions to the 13 CO 2 breath test method are reviewed and related to the 14 CO 2 breath test proposals. In spite of several advantages of 13 C-labelled agents, some dissatisfaction has remained with the tests, especially at using them with infants. It is the necessity of face masks and the uncertainty to consider endogeneous CO 2 contributions diluting the exhaled 13 CO 2 . The problems are avoided if the other molecule site of the drug is labelled which is known to be eliminated via urine. With 15 N as a tracer, a suitable urine test using [ 15 N]-methacetin as agent has been proposed and put into practice. (author)

  9. Students' Changing Attitudes and Aspirations Towards Physics During Secondary School

    Science.gov (United States)

    Sheldrake, Richard; Mujtaba, Tamjid; Reiss, Michael J.

    2017-11-01

    Many countries desire more students to study science subjects, although relatively few students decide to study non-compulsory physics at upper-secondary school and at university. To gain insight into students' intentions to study non-compulsory physics, a longitudinal sample (covering 2258 students across 88 secondary schools in England) was surveyed in year 8 (age 12/13) and again in year 10 (age 14/15). Predictive modelling highlighted that perceived advice, perceived utility of physics, interest in physics, self-concept beliefs (students' subjective beliefs of their current abilities and performance) and home support specifically orientated to physics were key predictors of students' intentions. Latent-transition analysis via Markov models revealed clusters of students, given these factors at years 8 and 10. Students' intentions varied across the clusters, and at year 10 even varied when accounting for the students' underlying attitudes and beliefs, highlighting that considering clusters offered additional explanatory power and insight. Regardless of whether three-cluster, four-cluster, or five-cluster models were considered, the majority of students remained in the same cluster over time; for those who transitioned clusters, more students changed clusters reflecting an increase in attitudes than changed clusters reflecting a decrease. Students in the cluster with the most positive attitudes were most likely to remain within that cluster, while students in clusters with less positive attitudes were more likely to change clusters. Overall, the cluster profiles highlighted that students' attitudes and beliefs may be more closely related than previously assumed, but that changes in their attitudes and beliefs were indeed possible.

  10. Differences in Chemical Engineering Student-Faculty Interactions by Student Age and Experience at a Large, Public, Research University

    Science.gov (United States)

    Ciston, Shannon; Sehgal, Sanya; Mikel, Tressa; Carnasciali, Maria-Isabel

    2018-01-01

    Adult undergraduate students aged 25+ in engineering disciplines are an important demographic bringing a wealth of life experience to the classroom. This study uses qualitative data drawn from semi-structured interviews with two groups of undergraduate chemical engineering students at a large, public research university: adult students with…

  11. A rare balanced nonrobertsonian translocation involving acrocentric chromosomes: Chromosome abnormality of t(13;15(p11.2;q22.1

    Directory of Open Access Journals (Sweden)

    Dalvi Rupa

    2016-01-01

    Full Text Available BACKGROUND: Balanced non-robertsonian translocation (RT, involving acrocentric chromosomes, is a rare event and only a few cases are reported. Most of the RTs are balanced involving acrocentric chromosomes with the breakpoints (q10;q10. MATERIALS AND METHODS: Chromosome analysis was performed as per standard procedure – Giemsa-trypsin banding with 500 band resolution was analyzed for chromosome identification. RESULTS: In the present study, we report a rare balanced non-RTs involving chromosomes 13 and 15 with cytogenetic finding of 46, XX, t(13;15(p11.2;q22.1. CONCLUSION: To the best of our knowledge, this is the first such report of an unusual non-RT of t(13:15 with (p11.2;q22.1 break points.

  12. Developmental continuity of oppositional defiant disorder subdimensions at ages 8, 10, and 13 years and their distinct psychiatric outcomes at age 16 years.

    Science.gov (United States)

    Whelan, Yvonne M; Stringaris, Argyris; Maughan, Barbara; Barker, Edward D

    2013-09-01

    To test the developmental continuity, interrelationships, and predictive associations of the oppositional defiant disorder (ODD) subdimensions of irritable, headstrong, and hurtful. Data were collected from 6,328 mother-child pairs participating in the Avon Longitudinal Study of Parents and Children (United Kingdom). Developmental continuity for each subdimension was strong and interrelationships indicated that headstrong was associated mainly with irritable, whereas irritable did not cross associate with other ODD subdimensions; and hurtful was associated with lower levels of headstrong. With regard to associations at age 16 years, irritable at age 13 years was associated with depression, whereas headstrong at 13 was associated with delinquency and callous attitude; at age 13, hurtful failed to associate with any of the 3 age 16 outcomes. The results suggest that the ODD headstrong and irritable subdimensions are developmentally distinct, with small cross-over (i.e., headstrong to irritable), and are associated with unique outcomes. Hurtful does not appear to be associated with future maladjustment in children. Copyright © 2013 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.

  13. Assessment of Cognitive Outcome Measures in Teenagers with 15q13.3 Microdeletion Syndrome

    Science.gov (United States)

    Crutcher, Emeline; Ali, May; Harrison, John; Sovago, Judit; Gomez-Mancilla, Baltazar; Schaaf, Christian P.

    2016-01-01

    15q13.3 microdeletion syndrome causes a spectrum of cognitive disorders, including intellectual disability and autism. We aimed to determine if any or all of three cognitive testing systems (the KiTAP, CogState, and Stanford-Binet) are suitable for assessment of cognitive function in affected individuals. These three tests were administered to ten…

  14. A Survey on Mental Health Status of Adult Population Aged 15 and above in the Province of Sistan and Bluchestan, Iran.

    Science.gov (United States)

    Noorbala, Ahmad Ali; Bagheri Yazdi, Seyed Abbas; Faghihzadeh, Soghrat; Kamali, Koorosh; Faghihzadeh, Elham; Hajebi, Ahmad; Akhondzadeh, Shahin; Shakiba, Mansour; Sargazi, Fatemah; Shahriari, Shirin

    2017-11-01

    This research aims to determine the mental health status of population aged 15 and over in the province of Sistan and Baluchestan in 2015. The statistical population of this cross-sectional field survey consisted of residents of urban and rural areas of Sistan and Baluchestan province in Iran. An estimated sample size of 1200 people was chosen using systematic random cluster sampling. The access was provided by the contribution of Geographical Post Office of Zahedan, Zabol, and Saravan cities. The General Health Questionnaire-28 (GHQ-28) was used as the screening tool for mental disorders. Data analysis in the current study was carried out using the SPSS-18 software. Using GHQ traditional scoring method, the results showed that 15.1% of individuals (17.2% of females and 13% of males) were suspected of mental disorders. The prevalence of suspected cases of mental disorders was 19% in urban and 13.5% in rural areas. It also showed that somatization and anxiety symptoms were more prevalent than social dysfunction and depression symptoms, and were more common in women than men. The results of this research also showed that the prevalence of suspected cases of mental disorders increased with aging. Such disorders were more common in females, age group of 65 and above, people living in urban areas, divorced and widowed, illiterate and retired individuals compared with the other groups. The results of this study showed that about a sixth of the people in the province were suspected to have mental disorders. Therefore, it is mandatory for the provincial public health authorities to take the needed steps to ensure that necessary requirements encompassing prevention and promotion of mental health are implemented.

  15. A Comparison of body mass index and daily step numbers of secondary school and high school students according to age and gender

    Directory of Open Access Journals (Sweden)

    Özcan Saygın

    2017-12-01

    Full Text Available Aim: The purpose of this study is to compare the body mass index and daily steps number of secondary and high school students in Mugla region according to age and gender. Material and Methods: A total of 1851 volunteer students (682 secondary school students and 1169 high school students participated in this study. Physical activity level was determined by measuring daily step numbers of students with a pedometer. Body mass index (kg/m2 was calculated by utilizing from height and weight measurements in order to find body composition. Acquired data was recorded in SPSS (18.0 program. In order to find a difference in body composition and physical activity level between gender, Independent t-test was applied. One-way Anova was applied in order to find the differences among ages. Tukey HSD Analysis was used to find from which age the difference stemmed from. Frequencies and percentages values were calculated to assess the number of daily steps and body mass index standards, and chi-square analysis was used to find differences according to sex. Results: As a result of the statistical analyse; statistically significant difference was found in the physical activity level of secondary school students, it was also found both high school student’s body composition and physical activity levels of high school students according to gender (p<0.05. While the body mass index values of both male and female students tend to increase with age, the physical activity level of both students tends to decrease with age. Statistically, a significant difference was found when the daily step count standards were compared by sex (X2=23.999 p=0.000. It was found that 65.91% (n=698 of the female students and 49.87% (n=395 of the male students were below the normal values of the daily step counts. Statistically, a significant difference was found when the body mass index standards were compared by sex (X2=15.702, p=0.000. It was seen that 16.90% of female students (n=179

  16. Recovery rates of infants with cryptorchidism before 15 months of age

    Directory of Open Access Journals (Sweden)

    2014-01-01

    Full Text Available Background and objectives: Cryptorchidism or undescended testicle, with a prevalence of 33 percent in preterm and 3-5 percent in term infants, is the most common congenital abnormality in newborn boys. The present study aimed to assess the recovery rate and urinary tract infection among infants with cryptorchidism during the first 15 months of their life.         Methods: This cross-sectional descriptive study was conducted on 47 infants with cryptorchidism in Zahedan city (Iran in 2012. The infants’ birth weight, preterm/term birth, delivery method, and affected testicle along with maternal age, history of urinary tract infection during pregnancy, and number of pregnancies were collected. Information about the infants’ urinary tract infection and recovery from cryptorchidism was collected through observations and trimonthly phone calls until the 15th month after birth. Percentage and mean were used for data analysis. Results: Of the 47 studied infants, 63.82 percent were premature, 59.57 percent had right-side cryptorchidism, and 80.60 percent developed urinary tract infection at least once. The highest incidence of urinary tract infection (29.8 percent was seen at the age of three months old. The majority of infants (91.5 percent recovered during the course of the study and the recovery rate at the fifth, 10th, and 15th months were 31.9 percent, 38.3 percent and 21.3 percent,respectively. Conclusion: This study revealed the high prevalence of urinary tract infection among infants with cryptorchidism. It also showed that most infants with cryptorchidism recover within 15 months of age.

  17. Antecedents of Suicide among Youth Aged 11–15: A Multistate Mixed Methods Analysis

    Science.gov (United States)

    Vivolo-Kantor, Alana M.; Logan, Joseph E.; Leemis, Ruth W.

    2018-01-01

    Suicide is the second leading cause of death for youth aged 11 to 15, taking over 5,500 lives from 2003 to 2014. Suicide among this age group is linked to risk factors such as mental health problems, family history of suicidal behavior, biological factors, family problems, and peer victimization and bullying. However, few studies have examined the frequency with which such problems occur among youth suicide decedents or the context in which decedents experience these risk factors and the complex interplay of risk that results in a decedent’s decision to take his/her own life. Data from a random sample of 482 youth (ages 11–15) suicide cases captured in the National Violent Death Reporting System from 2003 to 2014 were analyzed. The sample had fewer girls than boys (31 vs. 69 %) and comprised primarily White youth (79 %), but also African Americans (13 %), Asians (4 %), and youth of other races (4 %). Narrative data from coroner/medical examiner and law enforcement investigative reports were coded and analyzed to identify common behavioral patterns that preceded suicide. Emergent themes were quantified and examined using content and constant comparative analysis. Themes regarding antecedents across multiple levels of the social ecology emerged. Relationship problems, particularly with parents, were the most common suicide antecedent. Also, a pattern demonstrating a consistent progression toward suicidal behavior emerged from the data. Narratives indicated that youth were commonly exposed to one or more problems, often resulting in feelings of loneliness and burdensomeness, which progressed toward thoughts and sometimes plans for or attempts at suicide. Continued exposure to negative experiences and thoughts/plans about suicide, and/or self-injurious acts resulted in an acquired capacity to self-harm, eventually leading to suicide. These findings provide support for theories of suicidal behavior and highlight the importance of multi-level, comprehensive

  18. Tracking spatial distribution of human-derived wastewater from Davis Station, East Antarctica, using δ15N and δ13C stable isotopes

    International Nuclear Information System (INIS)

    Corbett, Patricia A.; King, Catherine K.; Mondon, Julie A.

    2015-01-01

    Highlights: • Elevated δ15N and δ13C observed in fish tissue up to 4 km from the Davis Station wastewater outfall. • δ15N decreased stepwise with concentrations decreasing with distance from the discharge point. • The trend observed for δ13C almost mirrored δ15N. • Current wastewater treatment practices are insufficient to avoid uptake of contaminants in fish. - Abstract: Stable isotope ratios, δ15N and δ13C were effectively used to determine the geographical dispersion of human derived sewage from Davis Station, East Antarctica, using Antarctic rock cod (Trematomus bernacchii). Fish within 0–4 km downstream of the outfall exhibited higher δ15N and δ13C values relative to reference sites. Nitrogen in particular showed a stepped decrease in δ15N with increasing distance from the discharge point by 1–2‰. Stable isotopes were better able to detect the extent of wastewater contamination than other techniques including faecal coliform and sterol measures. Uptake and assimilation of δ15N and δ13C up to 4 km from the outfall adds to growing evidence indicating the current level of wastewater treatment at Davis Station is not sufficient to avoid impact to the surrounding environment. Isotopic assimilation in T. bernacchii is a viable biomarker for investigation of initial sewage exposure and longer term monitoring in the future

  19. Musculoskeletal disorders among first-year Ghanaian students in a ...

    African Journals Online (AJOL)

    Keywords: Musculoskeletal disorders, nursing students, functional impairment. ... female sex6,7,14,17, lack of regular exer- cise13,18 and psychosocial stress and mental pressure6,15 .... students in China and Malaysia respectively. There is.

  20. 15 CFR 50.5 - Fee structure for age search and citizenship information.

    Science.gov (United States)

    2010-01-01

    ... THE CENSUS § 50.5 Fee structure for age search and citizenship information. Type of service Fee... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Fee structure for age search and citizenship information. 50.5 Section 50.5 Commerce and Foreign Trade Regulations Relating to Commerce and...

  1. The prevalence of obesity in chilhood 6-15 years of age in denizli

    OpenAIRE

    Semiz, Serap; Özdemir, Özmert M.a.; Özdemir, Ayşegül Sözeri

    2008-01-01

    In the last 20 years the increasing frequency of obesity is observed worldwide. It is understood thatobesity among children and adolescents can persist into adulthood. Therefore, these subjects shouldbe diagnosed earlier and should be treated as indicated. For this purpose we planned to investigate theprevalence of obesity in children 6-15 years old in Denizli.Eight hundred and fifty children between 6-15 years of age (389 girls, 461 boys, mean age 10.7±2.3years) in Denizli were enrolled in t...

  2. Influence of having breakfast on cognitive performance and mood in 13- to 20-year-old high school students: results of a crossover trial.

    Science.gov (United States)

    Widenhorn-Müller, Katharina; Hille, Katrin; Klenk, Jochen; Weiland, Ulrike

    2008-08-01

    The goal was to determine whether breakfast had effects on the cognitive performance and mood of high school students. A crossover trial was performed in boarding schools, involving 104 students between 13 and 20 years of age. The participants were randomly assigned to 2 equal-size groups on the morning of the first testing day. One half of the total sample received a standardized breakfast, whereas the other half received no breakfast. Seven days later, the treatment order was reversed. Measurements of cognitive function included standardized tests of attention and concentration, as well as tests of verbal and spatial memory. In addition, mood was rated with a self-administered questionnaire covering the dimensions of positive and negative affect, information uptake, arousal, and alertness. Statistical analysis consisted of repeated-measures analysis of variance. Breakfast had no effect on sustained attention among high school students. Visuospatial memory was improved in male students. Self-reported alertness improved significantly in the entire study population. Male students reported feeling more positive after consuming breakfast, compared with the fasting condition. This crossover trial demonstrated positive short-term effects of breakfast on cognitive functioning and self-reported alertness in high school students.

  3. Risk factors for unintentional poisoning in children aged 1-3 years in NSW Australia: a case-control study.

    Science.gov (United States)

    Schmertmann, Marcia; Williamson, Ann; Black, Deborah; Wilson, Leigh

    2013-05-24

    Unintentional poisoning in young children is an important public health issue. Age pattern studies have demonstrated that children aged 1-3 years have the highest levels of poisoning risk among children aged 0-4 years, yet little research has been conducted regarding risk factors specific to this three-year age group and the methodologies employed varied greatly. The purpose of the current study is to investigate a broad range of potential risk factors for unintentional poisoning in children aged 1-3 years using appropriate methodologies. Four groups of children, one case group (children who had experienced a poisoning event) and three control groups (children who had been 'injured', 'sick' or who were 'healthy'), and their mothers (mother-child dyads) were enrolled into a case-control study. All mother-child dyads participated in a 1.5-hour child developmental screening and observation, with mothers responding to a series of questionnaires at home. Data were analysed as three case-control pairs with multivariate analyses used to control for age and sex differences between child cases and controls. Five risk factors were included in the final multivariate models for one or more case-control pairs. All three models found that children whose mothers used more positive control in their interactions during a structured task had higher odds of poisoning. Two models showed that maternal psychiatric distress increased poisoning risk (poisoning-injury and poisoning-healthy). Individual models identified the following variables as risk factors: less proximal maternal supervision during risk taking activities (poisoning-injury), medicinal substances stored in more accessible locations in bathrooms (poisoning-sick) and lower total parenting stress (poisoning-healthy). The findings of this study indicate that the nature of the caregiver-child relationship and caregiver attributes play an important role in influencing poisoning risk. Further research is warranted to explore the

  4. Summary of NREL's FY13-FY15 Photovoltaic Subprogram

    Energy Technology Data Exchange (ETDEWEB)

    2017-03-31

    In this report, you will find summaries of the completed FY13-FY15 Photovoltaic projects that were funded within NREL. The summaries describe the initial motivation for the project; significant achievements, including publications, intellectual property, and collaborations; and remaining challenges. Among the NREL projects, you will find research of almost every major PV technology - from the next generation of silicon PV to relatively new organic PVs - as well as projects advancing PV module durability and characterization. Each of these projects was designed to support SunShot's goals, putting the United States one step closer to widespread use of low-cost, clean electricity.

  5. Proceedings of the National Silviculture Workshop: Density of Stocking Control; Eugene, Oregon; October 13-15, 1976

    Science.gov (United States)

    Jack H. Usher; Daniel B. Jones; A. R. Stage; Benjamin A. Roach; Gilbert B. Schubert; Darrell W. Crawford; Gilbert H. Schubert; Walter Fox; Edward A. Smith; Richard E. Lowrey Sofes; Richard F. Watt

    1976-01-01

    The 1976 National Silviculture Workshop was held in Eugene, Oregon, on October 13-15, 1976. The objectives were to discuss second growth management of individual stands, with particular emphasis on the control of stand density.

  6. Correlation between the synthetic origin of methamphetamine samples and their 15N and 13C stable isotope ratios

    International Nuclear Information System (INIS)

    Billault, Isabelle; Courant, Frederique; Pasquereau, Leo; Derrien, Solene; Robins, Richard J.; Naulet, Norbert

    2007-01-01

    The active ingredient of ecstasy, N-methyl-3,4-methyldioxyphenylisopropylamine (MDMA) can be manufactured by a number of easy routes from simple precursors. We have synthesised 45 samples of MDMA following the five most common routes using N-precursors from 12 different origins and three different precursors for the aromatic moiety. The 13 C and 15 N contents of both the precursors and the MDMA samples derived therefrom were measured by isotope ratio mass spectrometry coupled to an elemental analyser (EA-IRMS). We show that within-pathway correlation between the 15 N content of the precursor and that of the derived MDMA can be strong but that no general pattern of correlation can be defined. Rather, it is evident that the δ 15 N values of MDMA are strongly influenced by a combination of the δ 15 N values of the source of nitrogen used, the route by which the MDMA is synthesised, and the experimental conditions employed. Multivariate analysis (PCA) based on the δ 15 N values of the synthetic MDMA and of the δ 15 N and δ 13 C values of the N-precursors leads to good discrimination between the majority of the reaction conditions tested

  7. Stable isotope analysis (δ (13)C and δ (15)N) of soil nematodes from four feeding groups.

    Science.gov (United States)

    Melody, Carol; Griffiths, Bryan; Dyckmans, Jens; Schmidt, Olaf

    2016-01-01

    Soil nematode feeding groups are a long-established trophic categorisation largely based on morphology and are used in ecological indices to monitor and analyse the biological state of soils. Stable isotope ratio analysis ((13)C/(12)C and (15)N/(14)N, expressed as δ (13)C and δ (15)N) has provided verification of, and novel insights into, the feeding ecology of soil animals such as earthworms and mites. However, isotopic studies of soil nematodes have been limited to date as conventional stable isotope ratio analysis needs impractically large numbers of nematodes (up to 1,000) to achieve required minimum sample weights (typically >100 µg C and N). Here, micro-sample near-conventional elemental analysis-isotopic ratio mass spectrometry (μEA-IRMS) of C and N using microgram samples (typically 20 µg dry weight), was employed to compare the trophic position of selected soil nematode taxa from four feeding groups: predators (Anatonchus and Mononchus), bacterial feeders (Plectus and Rhabditis), omnivores (Aporcelaimidae and Qudsianematidae) and plant feeder (Rotylenchus). Free-living nematodes were collected from conventionally and organically managed arable soils. As few as 15 nematodes, for omnivores and predators, were sufficient to reach the 20 µg dry weight target. There was no significant difference in δ (15)N (p = 0.290) or δ (13)C (p = 0.706) between conventional and organic agronomic treatments but, within treatments, there was a significant difference in N and C stable isotope ratios between the plant feeder, Rotylenchus (δ (15)N = 1.08 to 3.22 mUr‰, δ (13)C = -29.58 to -27.87 mUr) and all other groups. There was an average difference of 9.62 mUr in δ (15)N between the plant feeder and the predator group (δ (15)N = 9.89 to 12.79 mUr, δ (13)C = -27.04 to -25.51 mUr). Isotopic niche widths were calculated as Bayesian derived standard ellipse areas and were smallest for the plant feeder (1.37 mUr(2)) and the predators (1.73 mUr(2)), but largest for

  8. Stable isotope analysis (δ13C and δ15N of soil nematodes from four feeding groups

    Directory of Open Access Journals (Sweden)

    Carol Melody

    2016-09-01

    Full Text Available Soil nematode feeding groups are a long-established trophic categorisation largely based on morphology and are used in ecological indices to monitor and analyse the biological state of soils. Stable isotope ratio analysis (13C/12C and 15N/14N, expressed as δ13C and δ15N has provided verification of, and novel insights into, the feeding ecology of soil animals such as earthworms and mites. However, isotopic studies of soil nematodes have been limited to date as conventional stable isotope ratio analysis needs impractically large numbers of nematodes (up to 1,000 to achieve required minimum sample weights (typically >100 µg C and N. Here, micro-sample near-conventional elemental analysis–isotopic ratio mass spectrometry (μEA–IRMS of C and N using microgram samples (typically 20 µg dry weight, was employed to compare the trophic position of selected soil nematode taxa from four feeding groups: predators (Anatonchus and Mononchus, bacterial feeders (Plectus and Rhabditis, omnivores (Aporcelaimidae and Qudsianematidae and plant feeder (Rotylenchus. Free-living nematodes were collected from conventionally and organically managed arable soils. As few as 15 nematodes, for omnivores and predators, were sufficient to reach the 20 µg dry weight target. There was no significant difference in δ15N (p = 0.290 or δ13C (p = 0.706 between conventional and organic agronomic treatments but, within treatments, there was a significant difference in N and C stable isotope ratios between the plant feeder, Rotylenchus (δ15N = 1.08 to 3.22 mUr‰, δ13C = –29.58 to –27.87 mUr and all other groups. There was an average difference of 9.62 mUr in δ15N between the plant feeder and the predator group (δ15N = 9.89 to 12.79 mUr, δ13C = –27.04 to –25.51 mUr. Isotopic niche widths were calculated as Bayesian derived standard ellipse areas and were smallest for the plant feeder (1.37 mUr2 and the predators (1.73 mUr2, but largest for omnivores (3.83 mUr2

  9. Academic Achievement, Employment, Age and Gender and Students' Experience of Alternative School

    Science.gov (United States)

    Poyrazli, Senel; Ferrer-Wreder, Laura; Meister, Denise G.; Forthun, Larry; Coatsworth, J. Doug; Grahame, Kamini Maraj

    2008-01-01

    The purpose of this cross-sectional study was to explore associations between academic achievement, employment, gender, and age in relation to students' sense of school membership and perception of adults in school. The sample consisted of 102 secondary, alternative school students. Results indicated that students with a more positive perception…

  10. Physical Activity in U.S. Youth Aged 12-15 Years, 2012

    Science.gov (United States)

    ... Order from the National Technical Information Service NCHS Physical Activity in U.S. Youth Aged 12–15 Years, 2012 ... percentage of youth engaged in moderate-to-vigorous physical activity for at least 60 minutes each day? About ...

  11. Factors Associated with the Persistence of Bullying Victimization From 10th grade to 13th Grade: A Longitudinal Study.

    Science.gov (United States)

    Lien, Lars; Welander-Vatn, Audun

    2013-01-01

    Bullying among adolescents represents a major public health challenge. The aim of this study was to map the stability of bullying victimization across the transitional phase from lower to upper secondary school, and to describe the sociodemographic, academic and health-related characteristics of those bullied during the transition. 3674 Norwegian adolescents were followed longitudinally from the age of 15/16 until the age of 18/19, answering questionnaires about health, academic achievements, life events, lifestyle and sociodemography. The 337 participants reporting exposure to bullying victimization at age 15/16 were the target group, as we made comparisons between those reporting victimization only at the age of 15/16 (n=289) with the participants for whom the bullying had continued into later adolescence (n = 48). 14% of those victimized at age 15/16, reported continuation of bullying victimization into upper secondary school. These adolescents were significantly more likely to report having divorced parents, low parental educational level, poor self-perceived economy, muscle and skeletal pain, symptoms of mental distress, lower school marks in Norwegian and higher body-mass index (BMI) when group differences at age 18/19 were assessed through basic inferential statistical tests. However, the multivariate logistic regression analyses only revealed statistically significantly increased adjusted odds ratios for the variables mental distress and school-marks in Norwegian. The persistence of exposure to bullying from 10th grade to 13th grade is associated with mental health complaints and poor school performance. Preventive measures to take care of students being continuously bullied should be in place in secondary schools.

  12. Application of 13C and 15N stable isotope probing to characterize RDX degrading microbial communities under different electron-accepting conditions

    International Nuclear Information System (INIS)

    Cho, Kun-Ching; Lee, Do Gyun; Fuller, Mark E.; Hatzinger, Paul B.; Condee, Charles W.; Chu, Kung-Hui

    2015-01-01

    Highlights: • SIP characterized RDX-degrading communities under different e-accepting conditions. • Dominant RDX degradation pathways differed under different e-accepting conditions. • More complete detoxification of RDX occurred under methanogenic and sulfate-reducing conditions than under manganese(IV) and iron(III)-reducing conditions. - Abstract: This study identified microorganisms capable of using the explosive hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) or its metabolites as carbon and/or nitrogen sources under different electron-accepting conditions using 13 C and 15 N stable isotope probing (SIP). Mesocosms were constructed using groundwater and aquifer solids from an RDX-contaminated aquifer. The mesocosms received succinate as a carbon source and one of four electron acceptors (nitrate, manganese(IV), iron(III), or sulfate) or no additional electron acceptor (to stimulate methanogenesis). When RDX degradation was observed, subsamples from each mesocosm were removed and amended with 13 C 3 - or ring- 15 N 3 -, nitro- 15 N 3 -, or fully-labeled 15 N 6 -RDX, followed by additional incubation and isolation of labeled nucleic acids. A total of fifteen 16S rRNA sequences, clustering in α- and γ-Proteobacteria, Clostridia, and Actinobacteria, were detected in the 13 C-DNA fractions. A total of twenty seven sequences were derived from different 15 N-DNA fractions, with the sequences clustered in α- and γ-Proteobacteria, and Clostridia. Interestingly, sequences identified as Desulfosporosinus sp. (in the Clostridia) were not only observed to incorporate the labeled 13 C or 15 N from labeled RDX, but also were detected under each of the different electron-accepting conditions. The data suggest that 13 C- and 15 N-SIP can be used to characterize microbial communities involved in RDX biodegradation, and that the dominant pathway of RDX biodegradation may differ under different electron-accepting conditions

  13. Preschool Gender-Typed Play Behavior at Age 3.5 Years Predicts Physical Aggression at Age 13 Years.

    Science.gov (United States)

    Kung, Karson T F; Li, Gu; Golding, Jean; Hines, Melissa

    2018-05-01

    Gender differences in play behavior and physical aggression have been consistently reported. Theoretical perspectives concerning evolutionary, social, and social-cognitive mechanisms suggest that male-typical play behavior during childhood increases subsequent physical aggression. The evidence supporting these connections is limited, however. The present study investigated the association between gender-typed play behavior in early childhood and physical aggression in early adolescence using a sample drawn from a longitudinal, population study, the Avon Longitudinal Study of Parents and Children. Based on gender-typed play behavior as measured by the Pre-School Activities Inventory at age 3.5 years, samples of masculine (64 boys, 60 girls), feminine (80 boys, 66 girls), and randomly selected control children (55 boys, 67 girls) were recruited at age 13 years and administered the Reinisch Aggression Inventory. After controlling for a range of sociodemographic variables, maternal characteristics, and behavioral problems, including hyperactivity and conduct problems at age 3.5, significant group differences in physical aggression at age 13 were found among children classified as masculine, control, and feminine at age 3.5. Masculine children exhibited significantly more physical aggression than control children or feminine children, and control children exhibited significantly more physical aggression than feminine children. The association between gender-typed play behavior and physical aggression was not moderated by sex. These results suggest that the degree of childhood gender-typed play behavior independently predicts the degree of physical aggression at adolescence in boys and in girls.

  14. Proposition of decision limits for serum lipids in Brazilian children aged one to 13 years.

    Science.gov (United States)

    Slhessarenko, Natasha; Fontes, Cor J F; Slhessarenko, Maria Eduarda; Azevedo, Raymundo S; Andriolo, Adagmar

    2018-03-09

    To determine decision limits for total cholesterol, LDL-cholesterol, non-HDL cholesterol, HDL-cholesterol, and triglycerides in healthy children and adolescents from Cuiabá, Brazil. This was a cross-sectional study of 1866 healthy children and adolescents randomly selected from daycare centers and public schools in Cuiabá. The desirable levels of serum lipids were defined using the classic criteria, i.e., total cholesterol, LDL-cholesterol, non-HDL cholesterol, and triglycerides levels below the P75 percentile, and HDL-c above the P10 percentile. For CT, P75 was: 160mg/dL for the age range of 1 to <3 years, 170mg/dL for ≥3 to <9 years, and 176mg/dL for ≥9 to <13 years. For non-HDL cholesterol, it was 122mg/dL for the age range of 1 to <13 years. For LDL-c, it was 104mg/dL at the age range of 1 to <9 years and 106mg/dL from ≥9 to <13 years. For TG, it was 127mg/dL from 1 to <2 years; 98mg/dL from ≥2 to <6 years; and 92mg/dL from ≥6 to <13 years. As for HDL-cholesterol, P10 was 24mg/dL, 28mg/dL, 32mg/dL, and 36mg/dL, for the age ranges of 1 to <2 years, ≥2 to <3 years, ≥3 to <4 years, and ≥4 to <13 years, respectively. The decision limits for the serum lipid levels defined in this study differed from those observed in the current Brazilian and North-American guidelines, especially because it differentiates between the age ranges. Using these decision limits in clinical practice will certainly contribute to improve the diagnostic accuracy for dyslipidemia in this population group. Copyright © 2018 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

  15. Nitrogen Fertilizer and Straw Applications Affect Uptake of 13C,15N-Glycine by Soil Microorganisms in Wheat Growth Stages.

    Directory of Open Access Journals (Sweden)

    Lijie Yang

    Full Text Available This study investigated the influence of nitrogen (N fertilizer and straw on intact amino acid N uptake by soil microorganisms and the relationship between amino acid turnover and soil properties during the wheat growing season. A wheat pot experiment was carried out with three treatments: control (CK, N fertilizer (NF and N fertilizer plus rice straw (NS. We used stable isotope compound-specific analysis to determine the uptake of 13C,15N-glycine by soil microorganisms. In the NF treatment, microbial 13C,15N-glycine uptake was lower compared with CK, suggesting that inorganic N was the preferred N source for soil microorganisms. However, The application of straw with N fertilizer (in NS treatment increased microbial 13C,15N-glycine uptake even with the same amount of N fertilizer application. In this treatment, enzyme activities, soil microbial biomass C and microbial biomass N increased simultaneously because more C was available. Soil mineral N and plant N contents all decreased substantially. The increased uptake of intact 13C,15N-glycine in the NS treatment can be attributed to direct assimilation by soil microorganisms to satisfy the demand for N when inorganic N was consumed.

  16. Implementation of the Social Decision-Making Skills Curriculum on Primary Students (Grades 1-3) in Lebanon

    Science.gov (United States)

    El Hassan, Karma; Mouganie, Zeina

    2014-01-01

    This study investigated the effect of the Social Decision-Making Skills Curriculum (SDSC) on the emotional intelligence and the prosocial behaviors of primary students in Grades 1-3, in a private school in Lebanon. Students were trained in social problem-solving and social decision-making skills through the implementation of the SDSC. Participants…

  17. Smoking Prevalence and Related Factors Among Secondary and High School Students in Tokat Province

    Directory of Open Access Journals (Sweden)

    Gizem Emekdar

    2017-03-01

    Full Text Available Smoking Prevalence and Related Factors Among Secondary and High School Students in Tokat Province Objective: The tobacco epidemic is one of the biggest public health threats in the world. The majority of smokers in the adolescent group has started smoking at early ages. Smoking prevalence among adolescents are reported to be approximately 10%. This study was aimed to determine the prevalence of smoking and related factors among secondary and high school students in Tokat province. Method: Population of this cross-sectional study consists of secondary and high school students in Tokat. Sample size was calculated as 1072 by using proportional stratified cluster sampling method according to type of school, gender and age. The study has been completed with 1069 students (secondary school: 557, high school: 512. Sociodemographic characteristics and the smoking habits of students were determined through questionaries. The students who smoking at least one cigarette in a day were accepted as smokers. Results: 50.9% of secondary school students were male, mean age was 12.1±1.3, 74.5% lived in city, prevalence of smoking was 10.8% (male:17.3%, female:4% and it was higher for students with <70 (16.3% average school grades than those with ≥70 (6.8% (p<0.05. 52.3% of high school students were female, mean age was 16.2±1.3, 80.7% lived in city, prevalence of smoking was 18% (male:29.9%, female:7.1% and it was higher for students which have secondary or above maternal education level (23.8% than those students which have lower maternal education level (15.7%; higher in those whom parents live seperate or have died (42.3% than those whom parents live together (16.7%; higher in those that have average school grades <70 (23.8% than those with ≥70 (11.3% (p<0.05. Place of residence, income level and profession of parents were not significant effect on smoking prevalence. The most common cause of start smoking was curiosity (42.4%. Conclusions: Nearly one in

  18. Auto-inducing media for uniform isotope labeling of proteins with 15N, 13C and 2H

    International Nuclear Information System (INIS)

    Guthertz, Nicolas; Klopp, Julia; Winterhalter, Aurélie; Fernández, César; Gossert, Alvar D.

    2015-01-01

    Auto-inducing media for protein expression offer many advantages like robust reproducibility, high yields of soluble protein and much reduced workload. Here, an auto-inducing medium for uniform isotope labelling of proteins with 15 N, 13 C and/or 2 H in E. coli is presented. So far, auto-inducing media have not found widespread application in the NMR field, because of the prohibitively high cost of labeled lactose, which is an essential ingredient of such media. Here, we propose using lactose that is only selectively labeled on the glucose moiety. It can be synthesized from inexpensive and readily available substrates: labeled glucose and unlabeled activated galactose. With this approach, uniformly isotope labeled proteins were expressed in unattended auto-inducing cultures with incorporation of 13 C, 15 N of 96.6 % and 2 H, 15 N of 98.8 %. With the present protocol, the NMR community could profit from the many advantages that auto-inducing media offer

  19. Secular trends in menarcheal age in India-evidence from the Indian human development survey.

    Directory of Open Access Journals (Sweden)

    Praveen Kumar Pathak

    Full Text Available Evidence from a number of countries in Europe and North America point towards the secular declining trend in menarcheal age with considerable spatial variations over the past two centuries. Similar trends were reported in several developing countries from Asia, Africa and Latin America. However, data corroborating any secular trend in the menarcheal age of the Indian population remained sparse and inadequately verified.We examined secular trends, regional heterogeneity and association of socioeconomic, anthropometric and contextual factors with menarcheal age among ever-married women (15-49 years in India. Using the pseudo cohort data approach, we fit multiple linear regression models to estimate secular trends in menarcheal age of 91394 ever-married women using the Indian Human Development Survey.The mean age at menarche among Indian women was 13.76 years (95 % CI: 13.75, 13.77 in 2005. It declined by three months from 13.83 years (95% CI: 13.81, 13.85 among women born prior to 1955-1964, to nearly 13.62 years (95% CI: 13.58, 13.67 among women born during late 1985-1989. However, these aggregate national figures mask extensive spatial heterogeneity as mean age at menarche varied from 15.0 years in Himachal Pradesh during 1955-1964 (95% CI: 14.89-15.11 to about 12.1 years in Assam (95% CI: 11.63-12.56 during 1985-1989.The regression analysis established a reduction of nearly one month per decade, suggesting a secular decline in age at menarche among Indian women. Notably, the menarcheal age was significantly associated with the area of residence, geographic region, linguistic groups, educational attainment, wealth status, caste and religious affiliations among Indian women.

  20. Cyclotron production of molecules labelled with short-lived radioisotopes β+ emitters (15O, 13N, 11C) and their clinical uses

    International Nuclear Information System (INIS)

    Bougharouat, B.

    1981-01-01

    Clinical use of three short-lived radioisotopes: 15 O, 13 N and 11 C is studied on two complementary aspects. A production and purification system is realized; detection instruments in medical use are studied. The production of labelled molecules with the three radiotracers 15 O, 13 N, 11 C from the target bombardment with charged and accelerated particles was studied [fr

  1. Nursing Students' Attitudes Toward the Aged as a Function of Death Anxiety.

    Science.gov (United States)

    Blackie, Norman K.

    A 139-item questionnaire was constructed to account for additional variance in the attitudes and behaviors of student nurses toward the aged. This study was conducted to examine the effects of death anxiety on the attitudes and behaviors of student nurses toward old persons. To this end, 150 student nurses were surveyed. Eight scales were…

  2. Spectrum of Physics Comprehension

    Science.gov (United States)

    Blasiak, W.; Godlewska, M.; Rosiek, R.; Wcislo, D.

    2012-01-01

    The paper presents the results of research on the relationship between self-assessed comprehension of physics lectures and final grades of junior high school students (aged 13-15), high school students (aged 16-18) and physics students at the Pedagogical University of Cracow, Poland (aged 21). Students' declared level of comprehension was measured…

  3. 13C, 15N Resonance Assignment of Parts of the HET-s Prion Protein in its Amyloid Form

    International Nuclear Information System (INIS)

    Siemer, Ansgar B.; Ritter, Christiane; Steinmetz, Michel O.; Ernst, Matthias; Riek, Roland; Meier, Beat H.

    2006-01-01

    The partial 15 N and 13 C solid-state NMR resonance assignment of the HET-s prion protein fragment 218-289 in its amyloid form is presented. It is based on experiments measured at MAS frequencies in the range of 20-40 kHz using exclusively adiabatic polarization-transfer schemes. The resonance assignment within each residue is based on two-dimensional 13 C-- 13 C correlation spectra utilizing the DREAM mixing scheme. The sequential linking of the assigned residues used a set of two- and three-dimensional 15 N-- 13 C correlation experiments. Almost all cross peaks visible in the spectra are assigned, but only resonances from 43 of the 78 amino-acid residues could be detected. The missing residues are thought to be highly disordered and/or highly dynamic giving rise to broad resonance lines that escaped detection in the experiments applied. The line widths of the observed resonances are narrow and comparable to line widths observed in micro-crystalline samples. The 43 assigned residues are located in two fragments of about 20 residues

  4. Secular trends in age at menarche among Chinese girls from 24 ethnic minorities, 1985 to 2010.

    Science.gov (United States)

    Song, Yi; Ma, Jun; Agardh, Anette; Lau, Patrick W C; Hu, Peijin; Zhang, Bing

    2015-01-01

    Declining age at menarche has been observed in many countries. In China, a decrease of 4.5 months per decade in the average age at menarche among the majority Han girls has recently been reported. However, the trends in age at menarche among ethnic minority girls over the past 25 years remain unknown. To compare the differences in median age at menarche among girls aged 9-18 years across 24 ethnic minorities in 2010 and to estimate the trends in age at menarche in different ethnic minorities from 1985 to 2010. We used data from six cross-sectional Chinese National Surveys on Students' Constitution and Health (1985, 1991, 1995, 2000, 2005, and 2010). The median age at menarche was estimated by using probit analysis. In 2010, the ethnic minorities with the earliest age at menarche were the Koreans (11.79 years), Mongolians (12.44 years), and Zhuang (12.52 years). The three ethnic minorities with the latest age at menarche were the Sala (14.32 years), Yi (13.74 years), and Uighurs (13.67 years). From 1985 to 2010, the age at menarche declined in all 24 minority groups. The Lisu, Kazakh, and Korean minorities showed the largest reductions in age at menarche by 1.79 (pminorities showed the smallest reductions, with age at menarche declining by only 0.06 (p>0.05), 0.15 (p>0.05), and 0.15 (p>0.05) years, respectively, in the same period. A large variation in age at menarche was observed among different ethnic minorities, with the earliest age at menarche found among Korean girls. A reduction in the average age at menarche appeared among most of the ethnic minorities over time, and the largest decrease was observed in Lisu, Kazakh, and Korean girls. Thus, health education should focus on targeting the specific needs of each ethnic minority group.

  5. Synthesis and biosynthesis of {sup 13}C-, {sup 15}N-labeled deoxynucleosides useful for biomolecular structural determinations

    Energy Technology Data Exchange (ETDEWEB)

    Ashburn, D.A.; Garcia, K.; Hanners, J.L.; Silks, L.A. III; Unkefer, C.J. [Los Alamos National Laboratory, NM (United States)

    1994-12-01

    Currently, there is a great emphasis on elucidating the structure, function, and dynamics of DNA. Much of the research involved in this study uses nuclear magnetic resonance (NMR) spectroscopy. Effective use of NMR spectroscopy for DNA molecules with mw > 10,000 requires stable isotope enrichment. We present strategies for site-specific isotopic labeling of the purine bases adenosine and guanosine and the biosynthesis of (U-{sup 13}C, {sup 15}N) DNA from methylotropic bacteria. With commercially available 6-chloropurine, an effective two-step route leads to 2{prime}-deoxy-(amino-{sup 15}N)adenosine (dA). The resulting d(amino-{sup 15}N)A is used in a series of reactions to synthesize 2{prime}-deoxy-(2-{sup 13}C,1,amino-{sup 15}N{sub 2})guanosine or any combination thereof. An improved biosynthesis of labeled DNA has been accomplished using Methylobacterium extorquens AS1. Each liter of growth medium contains 4 g of methanol to yield 1 g of lyophilized cells. As much as 200 mg of RNA per liter of culture has been obtained. We are currently developing large-scale isolation protocols. General synthetic pathways to oligomeric DNA will be presented.

  6. 9-Hydroxyprostaglandin dehydrogenase in rat kidney cortex converts prostaglandin I2 into 15-keto-13,14-dihydro 6-ketoprostaglandin E1.

    Science.gov (United States)

    Pace-Asciak, C R; Domazet, Z

    1984-11-14

    15-Keto-13,14-dihydro 6-ketoprostaglandin E1 was positively identified by gas chromatography-mass spectrometry with negative-ion chemical ionisation detection from samples of rat kidney high-speed supernatant incubated with prostaglandin I2 in the presence of NAD+. A decreased formation of this product was observed when NAD+ was substituted with NADP+ and none was observed in the absence of nucleotide or substrate prostaglandin I2. Experiments with [9 beta-3H]prostaglandin I2 showed a time- and concentration-dependent loss of tritium which appeared as tritiated water, typical of reaction of [9 beta-3H]prostaglandin substrates with the enzyme, 9-hydroxyprostaglandin dehydrogenase. Time-course measurements of the appearance of tritiated water showed similar rates with 6-keto[9 beta-3H]prostaglandin F1 alpha and 15-keto-13,14-dihydro 6-keto[9 beta-3H]prostaglandin F1 alpha as substrates. These experiments suggest that the transformation of prostaglandin I2 and 6-ketoprostaglandin F1 alpha into the 15-keto-13,14-dihydro 6-ketoprostaglandin E1 catabolite occurs in this in vitro preparation via the corresponding 15-keto-13,14-dihydro catabolite of 6-ketoprostaglandin F1 alpha.

  7. Search for copy number variants in chromosomes 15q11-q13 and 22q11.2 in obsessive compulsive disorder

    Directory of Open Access Journals (Sweden)

    Grabe Hans

    2010-06-01

    Full Text Available Abstract Background Obsessive-compulsive disorder (OCD is a clinically and etiologically heterogeneous syndrome. The high frequency of obsessive-compulsive symptoms reported in subjects with the 22q11.2 deletion syndrome (DiGeorge/velocardiofacial syndrome or Prader-Willi syndrome (15q11-13 deletion of the paternally derived chromosome, suggests that gene dosage effects in these chromosomal regions could increase risk for OCD. Therefore, the aim of this study was to search for microrearrangements in these two regions in OCD patients. Methods We screened the 15q11-13 and 22q11.2 chromosomal regions for genomic imbalances in 236 patients with OCD using multiplex ligation-dependent probe amplification (MLPA. Results No deletions or duplications involving 15q11-13 or 22q11.2 were identified in our patients. Conclusions Our results suggest that deletions/duplications of chromosomes 15q11-13 and 22q11.2 are rare in OCD. Despite the negative findings in these two regions, the search for copy number variants in OCD using genome-wide array-based methods is a highly promising approach to identify genes of etiologic importance in the development of OCD.

  8. Peer victimization and subjective health among students reporting disability or chronic illness in 11 Western countries.

    Science.gov (United States)

    Sentenac, Mariane; Gavin, Aoife; Gabhainn, Saoirse Nic; Molcho, Michal; Due, Pernille; Ravens-Sieberer, Ulrike; Matos, Margarida Gaspar de; Malkowska-Szkutnik, Agnieszka; Gobina, Inese; Vollebergh, Wilma; Arnaud, Catherine; Godeau, Emmanuelle

    2013-06-01

    To compare the strength of the association between peer victimization at school and subjective health according to the disability or chronic illness (D/CI) status of students across countries. This study used data from 55 030 students aged 11, 13 and 15 years from 11 countries participating in the 2005-06 Health Behaviour in School-aged Children survey. Self-completed questionnaires were administered in classrooms. Multivariate models of logistic regression (controlled for confounding factors and countries) were used to investigate differences in the association between peer victimization and poor subjective health according to the D/CI status. Overall, 13.5% of the students reported having been bullied at least two or three times a month. The percentage of victims was significantly higher among those reporting D/CI than among others in all countries studied. Victims of bullying were more likely to report poor self-rated health, low life satisfaction and multiple health complaints. However, there were no differences in the associations between peer victimization and subjective health indicators according to the D/CI status. In all countries studied, students reporting D/CI were more likely to report being victims of bullying. Victims of bullying reported more negative subjective health outcomes regardless of their D/CI status. Although inclusive education is currently a major topic of educational policies in most countries, additional efforts should be made to improve the quality of the integration of students with D/CI.

  9. 17 CFR 240.15c1-3 - Misrepresentation by brokers, dealers and municipal securities dealers as to registration.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Misrepresentation by brokers...-The-Counter Markets § 240.15c1-3 Misrepresentation by brokers, dealers and municipal securities..., as used in section 15(c)(1) of the Act, is hereby defined to include any representation by a broker...

  10. REPETITIVE STRENGTH AMONG STUDENTS OF AGE 14

    Directory of Open Access Journals (Sweden)

    Besim Halilaj

    2014-06-01

    Full Text Available The study involved 82 male students of the primary school “Qamil Ilazi” in Kaçanik-Kosovo.Four movement tests, which test the repetitive strength, were conducted: 1. Pull-up, 2. Sit-Up, 3. Back extension, 4. Push-up.The main goal of this study was to verify the actual motor status, respectively the component of the repetitive strength among students of age 14 of masculine gender. In addition to verifying the actual motor status, another objective was to verify the relationship between the variables employed.Basic statistical parameters show a distribution which is not significantly different from the normal distribution, yielded highly correlative values among the repetitive strength tests. Space factorization resulted in extracting two latent squares defined as repetitive strength of arms factor, and repetitive strength of body factor.

  11. Objectively measured physical activity predicts hip and spine bone mineral content in children and adolescents ages 5 - 15 years: Iowa Bone Development Study

    Directory of Open Access Journals (Sweden)

    Kathleen F Janz

    2014-07-01

    Full Text Available This study examined the association between physical activity (PA and bone mineral content (BMC; g from middle childhood to middle adolescence and compared the impact of vigorous-intensity PA (VPA over moderate- to vigorous-intensity PA (MVPA. Participants from the Iowa Bone Development Study were examined at ages 5, 8, 11, 13, and 15 yr (n=369, 449, 452, 410, 307, respectively. MVPA and VPA (min/day were measured using ActiGraph accelerometers. Anthropometry was used to measure body size and somatic maturity. Spine BMC and hip BMC were measured via dual-energy x-ray absorptiometry. Sex-specific multi-level linear models were fit for spine BMC and hip BMC, adjusted for weight (kg, height (cm, linear age (yr, non-linear age (yr2, and maturity (pre peak height velocity vs. at/post peak height velocity. The interaction effects of PA×maturity and PA×age were tested. We also examined differences in spine BMC and hip BMC between the least (10th percentile and most (90th percentile active participants at each examination period. Results indicated that PA added to prediction of BMC throughout the 10-year follow-up, except MVPA did not predict spine BMC in females. Maturity and age did not modify the PA effect for males nor females. At age 5, the males at the 90th percentile for VPA had 8.5% more hip BMC than males in the 10th percentile for VPA. At age 15, this difference was 2.0%. Females at age 5 in the 90th percentile for VPA had 6.1% more hip BMC than those in the 10th percentile for VPA. The age 15 difference was 1.8%. VPA was associated with BMC at weight-bearing skeletal sites from childhood to adolescence, and the effect was not modified by maturity or age. Our findings indicate the importance of early and sustained interventions that focus on VPA. Approaches focused on MVPA may be inadequate for optimal bone health, particularly for females.

  12. A Case of Acute Myeloid Leukemia with a Previously Unreported Translocation (14; 15 (q32; q13

    Directory of Open Access Journals (Sweden)

    Mohamad Khawandanah

    2014-01-01

    Full Text Available Background. We hereby describe what we believe to be the first reported case of t (14; 15 (q32; q13 associated with acute myeloid leukemia (AML. Methods. PubMed, Embase, and OVID search engines were used to review the related literature and similar published cases. Case. A47-year-old female presented in December 2011 with AML (acute myelomonocytic leukemia with normal cytogenetics; molecular testing revealed FLT-3 internal tandem duplication (ITD mutation, while no mutations involving FLT3 D385/I836, NPM1 exon 12, or KIT exons 8 and 17 were detected. She was induced with 7 + 3 (cytarabine + idarubicin and achieved complete remission after a second induction with high-dose cytarabine (HiDAC followed by uneventful consolidation. She presented 19 months after diagnosis with relapsed disease. Of note, at relapse cytogenetic analysis revealed t (14; 15 (q32; q13, while FLT-3 analysis showed a codon D835 mutation (no ITD mutation was detected. She proved refractory to the initial clofarabine-based regimen, so FLAG-idarubicin then was used. She continued to have persistent disease, and she was discharged on best supportive care. Conclusion. Based on this single case of AML with t (14; 15 (q32; q13, this newly reported translocation may be associated with refractory disease.

  13. Age of smoking initiation, tobacco habits and risk perception among primary, middle and high school students in Southern Italy

    Directory of Open Access Journals (Sweden)

    Margherita Ferrante

    2010-09-01

    Full Text Available

    Aim: The aim of this study was to find out at what age children start smoking, as well as their tobacco habits and risk perceptions according to the different school-age groups.

    Methods: A cross-sectional survey was carried out in 2007; it involved around 1700 students of the Catania province, in Southern Italy. The students filled in a structured tobacco questionnaire. They did it anonymously in the classrooms. Main outcome measures were initiation of smoking, smoking habits, number of cigarettes smoked per day and risk perception.

    Results: From the first year of the primary school to the last year of the high school the proportion of daily smokers increased from 0.0% to 11.8% for girls and from 0.8% to 12.7% for boys. For both genders the initiation of smoking habits occurred mainly at age 10 to 13. Finally, girls had a better risk perception.

    Conclusions: Studying young people’s tobacco habits over time gives an understanding of when preventive measures have to be implemented. In order to influence smoking attitudes, these preventive interventions must be put in place before children start experimenting tobacco.

  14. Occlusal caries risk assessment using Cariogram analysis in student aged 11-12 years

    Directory of Open Access Journals (Sweden)

    Riana Wardani

    2017-03-01

    Full Text Available ABSTRACT   Introduction: Basic Health Research 2013 showed Dental Caries Index in school age student in West Java was lower than the expected target, with occlusal surface as most affected part. The purpose of this study was to determine the risk status of dental caries in school age student by using cariogram analysis. Methods: Observational research. Study was conducted on 30 student aged 11-12 years with caries high risk on occlusal surfaces. Purposive sampling was taken from students of SDN Cikawari and SDN Mekarjaya Bandung Regency with high DMF-S index. Inclusion criteria: male and female, aged 11-12 years, good systemic health, SDN Mekarjaya and SDN Cikawari Bandung Regency students. Exclusion criteria: suffering from systemic disorder, currently in long-term antibiotic therapy, orthodontic appliance usage. Case history, eating habits and intake of fluoride, caries experience, salivary volume and buffering capacity of each sample was examined using cariogram examination method. Results: The cariogram analysis showed 43% chance of caries avoidance. Diet control was 23.3%, includes two factors: sugary foods and eating frequency. Bacteria control was 11.9% by evaluating both bacterial factors (the amount of plaque and the bacteria Streptococcus mutans. Vulnerability control was 14.4%, including caries prevention by the continuation of fluorine program and other conditions control that affect salivary secretions. Conclusion: Based on cariogram analysis found that all samples who had occlusal surfaces caries were at a high risk category, but still having moderate potential of avoiding new caries occurrence by controlling risk factors. Keywords: Cariogram analysis, Occlusal caries, Aged 11-12 years

  15. [Alcohol use and health-risk behaviours among academic students in Podkarpackie].

    Science.gov (United States)

    Zadarko-Domaradzka, Maria; Zadarko, Emilian; Barabasz, Zbigniew; Sobolewski, Marek

    2013-01-01

    Alcohol over-use is one of the risk behaviour and has harmful effects on health. In the whole European Region ever forth death among 15-29 years old people is caused by alcohol over. use. The aim of the paper is to present the degree of alcohol consumption propagation among academic stu. dents in Podkarpackie, as well as estimate the occurrence of hazardous drinking. Anonymous questionnaire survey was conducted among academic students in 2010. Chi-square test was used for statistical analysis. There is statistical difference regarding alcohol use between women and men. Men report to drink more and more frequent. Regular alcohol use was declared by 11.9% of men and 2.3% of women. Hazardous drinking was reported by 20.7% students. Age does not statistically differ the occurrence of hazardous drinking. However, it is interesting that although among the group of 19 years old, every seventh student reports hazardous drinking, among the other groups it was reported by every fifth student. More students from urban areas (24%), than from rural areas (18%) report hazardous drinking. Students living in dormitory almost twice more frequent are at the risk of hazardous drinking (29%), than those living with parents (17%). Among female students hazardous drinking was reported by the following faculties: touristic and recreation (24%), law(13%), medical (14%) and mathematic-environmental (15%). Among men students hazardous drinking was highly reported by law and administration faculty students (33%). Among hazardous drinking students as many as 45% regularly smoke cigarettes.

  16. Traceability of animal meals in Japanese quail eggs using the technique of 13C e 15N* stable isotopes

    Directory of Open Access Journals (Sweden)

    C Mori

    2013-03-01

    Full Text Available The objective of this study was to trace the inclusion of bovine meat and bone meal (BMBM in the diet of Japanese quails by analyzing eggs and egg fractions (yolk and albumen by the technique of carbon-13 (13C and nitrogen-15 (15N stable isotopes. In the trial, 120 Japanese quails were distributed in six treatments with four replicates of five birds each. The following treatments were applied: feed based on corn and soybean meal, containing graded BMBM inclusions (0, 1, 2, 3, 4 or 5%. After 42 days, 20 eggs per treatment were randomly collected for three consecutive days. Ten eggs were used for yolk and albumen sample collection, and ten for total egg sample collection. It was possible to detect the dietary inclusion of 1% BMBM in the egg and its fractions. Therefore, the technique of isotopes 13C and 15N is able of tracing since 1% inclusion level of BMBM in the diet of Japanese quails in eggs and their fractions.

  17. Socio-motivational moderators—two sides of the same coin? Testing the potential buffering role of socio-motivational relationships on achievement drive and test anxiety among German and Canadian secondary school students

    Science.gov (United States)

    Hoferichter, Frances; Raufelder, Diana; Eid, Michael

    2015-01-01

    The current cross-national study investigates the potential buffering role of socio-motivational relationships for the association of achievement drive (AD) and test anxiety (TX) in secondary school students from Canada and Germany. One thousand and eighty-eight students (54% girls, Mage = 13.71, SD = 0.53, age span 12–15 years) from the state of Brandenburg and 389 students from Quebéc (55.9% girls, Mage = 13.43, SD = 0.82, age span 12–16 years) were asked about their socio-motivational relationships with their teachers and peers, their drive for achievement, and TX. Multigroup latent moderated structural equations were conducted to test for the moderator role of socio-motivational relationships that would buffer feelings of TX related to the drive for achievement. The analyses revealed the two-sided role socio-motivational relationships can have for students with different levels of AD; intensifying or mitigating feelings of TX. Thereby, the results of this study extend the buffering hypothesis by Cohen and Wills (1985). Cross-national differences between Canada and Germany were found concerning the studied moderators on the association of AD and TX: While for German students teacher–student relationships acted as moderator, for Canadian students student–student relationships and teachers acting as positive motivators displayed a moderator role. PMID:26583000

  18. Volume-dependent hemodynamic effects of blood collection in canine donors - evaluation of 13% and 15% of total blood volume depletion

    Directory of Open Access Journals (Sweden)

    RUI R.F. FERREIRA

    2015-03-01

    Full Text Available Background: There is no consensus regarding the blood volume that could be safely donated by dogs, ranging from 11 to 25% of its total blood volume (TBV. No previous studies evaluated sedated donors.Aim: To evaluate the hemodynamic effects of blood collection from sedated and non-sedated dogs and to understand if such effects were volume-dependent.Materials and Methods: Fifty three donations of 13% of TBV and 20 donations of 15% TBV were performed in dogs sedated with diazepam and ketamine. Additionally, a total of 30 collections of 13% TBV and 20 collections of 15% TBV were performed in non-sedated dogs. Non-invasive arterial blood pressures and pulse rates were registered before and 15 min after donation. Results: Post-donation pulse rates increased significantly in both sedated groups, with higher differences in the 15% TBV collections. Systolic arterial pressures decreased significantly in these groups, while diastolic pressures increased significantly in 13% TBV donations. Non-sedated groups revealed a slight, but significant, SBP decrease. No clinical signs related to donations were registered.Conclusion: These results suggest that the collection of 15% TBV in sedated donors induces hemodynamic variations that may compromise the harmlessness of the procedure, while it seems to be a safe procedure in non-sedated dogs.

  19. Aptidão física relacionada ao desempenho motor em escolares de sete a 15 anos Physical fitness related to motor performance in scholars aged seven to 15 years

    Directory of Open Access Journals (Sweden)

    Samuel Carvalho Dumith

    2010-03-01

    Full Text Available Os benefícios do desenvolvimento da aptidão física sobre a saúde estão bem evidenciados na literatura científica. O objetivo do presente estudo foi descrever a aptidão física relacionada ao desempenho motor de crianças e adolescentes e examinar as diferenças de acordo com sexo, idade, tipo de escola (pública ou privada e região geográfica da escola (urbana ou rural. Uma bateria de cinco testes motores foi aplicada a 526 alunos entre sete e 15 anos do ensino fundamental de Rio Grande, RS: salto em distância parado, arremesso de "medicine-ball", barra modificada, corrida de 20 metros e quadrado. Os resultados apontam que o desempenho em todos os testes foi superior para os rapazes e aumentou diretamente com a faixa etária. Estes foram os principais preditores da aptidão física dentre as variáveis examinadas. O tipo de escola só teve influência sobre o desempenho no teste de arremesso de "medicine-ball", em que alunos da rede privada obtiveram valores médios maiores. Escolares da zona urbana atingiram um melhor desempenho em todos os testes, exceto no teste de barra modificada (sem diferença por região geográfica. A realização de pesquisas com o mesmo enfoque em outras regiões do Brasil permitirá explorar a consistência destes achados e compreender possíveis diferenças.There is strong evidence regarding the benefits of physical fitness development upon health. The aim of this study was to describe the physical fitness related to motor performance in children and adolescents, and to examine if there are differences according to sex, age, type of school (public or private and geographic region (urban or rural. A battery comprising of five motor tests were administered to 526 students aged seven to 15 years from elementary schools of Rio Grande, Brazil: stationary long jump, medicine-ball throw, modified pull-up, 20-meter run and 4-meter shuttle-run. The results indicate that the performance in all tests were higher

  20. Determinants of Personality Traits of School-Age Children : Evidence from Japanese Students at Age 12

    OpenAIRE

    Hojo, Masakazu

    2017-01-01

    It has been widely recognized among economists that non-cognitive ability, such as self-control, self-esteem, and personality traits, has a great power in predicting social and economic success. Using survey data from students at age 12 and their parents living in Japan, this paper explores the determinants of personality traits of school-age children. Personality traits are measured by students’ answers for questions concerning daily and school life, and we constructed five measures of perso...

  1. Clinical Features of Human Metapneumovirus Infection in Ambulatory Children Aged 5-13 Years.

    Science.gov (United States)

    Howard, Leigh M; Edwards, Kathryn M; Zhu, Yuwei; Griffin, Marie R; Weinberg, Geoffrey A; Szilagyi, Peter G; Staat, Mary A; Payne, Daniel C; Williams, John V

    2018-05-15

    We detected human metapneumovirus (HMPV) in 54 (5%) of 1055 children aged 5 to 13 years with acute respiratory illness (ARI) identified by outpatient and emergency department surveillance between November and May 2003-2009. Its clinical features were similar to those of HMPV-negative ARI, except a diagnosis of pneumonia was more likely (13% vs 4%, respectively; P = .005) and a diagnosis of pharyngitis (7% vs 24%, respectively; P = .005) was less likely in patients with HMPV- positive ARI than those with HMPV-negative ARI.

  2. 12/15 Lipoxygenase regulation of colorectal tumorigenesis is determined by the relative tumor levels of its metabolite 12-HETE and 13-HODE in animal models.

    Science.gov (United States)

    Chang, Jian; Jiang, Li; Wang, Yinqiu; Yao, Bing; Yang, Shilin; Zhang, Bixiang; Zhang, Ming-Zhi

    2015-02-20

    Colorectal cancer (CRC) continues to be a major cause of morbidity and mortality. The arachidonic acid (AA) pathway and linoleic acid (LA) pathway have been implicated as important contributors to CRC development and growth. Human 15-lipoxygenase 1 (15-LOX-1) converts LA to anti-tumor 13-S-hydroxyoctadecadienoic acid (13-HODE)and 15-LOX-2 converts AA to 15-hydroxyeicosatetraenoic acid (15-HETE). In addition, human 12-LOX metabolizes AA to pro-tumor 12-HETE. In rodents, the function of 12-LOX and 15-LOX-1 and 15-LOX-2 is carried out by a single enzyme, 12/15-LOX. As a result, conflicting conclusions concerning the role of 12-LOX and 15-LOX have been obtained in animal studies. In the present studies, we determined that PD146176, a selective 15-LOX-1 inhibitor, markedly suppressed 13-HODE generation in human colon cancer HCA-7 cells and HCA-7 tumors, in association with increased tumor growth. In contrast, PD146176 treatment led to decreases in 12-HETE generation in mouse colon cancer MC38 cells and MC38 tumors, in association with tumor inhibition. Surprisingly, deletion of host 12/15-LOX alone led to increased MC38 tumor growth, in association with decreased tumor 13-HODE levels, possibly due to inhibition of 12/15-LOX activity in stroma. Therefore, the effect of 12/15-LOX on colorectal tumorigenesis in mouse models could be affected by tumor cell type (human or mouse), relative 12/15 LOX activity in tumor cells and stroma as well as the relative tumor 13-HODE and 12-HETE levels.

  3. Organic vs. conventional grassland management: do (15)N and (13)C isotopic signatures of hay and soil samples differ?

    Science.gov (United States)

    Klaus, Valentin H; Hölzel, Norbert; Prati, Daniel; Schmitt, Barbara; Schöning, Ingo; Schrumpf, Marion; Fischer, Markus; Kleinebecker, Till

    2013-01-01

    Distinguishing organic and conventional products is a major issue of food security and authenticity. Previous studies successfully used stable isotopes to separate organic and conventional products, but up to now, this approach was not tested for organic grassland hay and soil. Moreover, isotopic abundances could be a powerful tool to elucidate differences in ecosystem functioning and driving mechanisms of element cycling in organic and conventional management systems. Here, we studied the δ(15)N and δ(13)C isotopic composition of soil and hay samples of 21 organic and 34 conventional grasslands in two German regions. We also used Δδ(15)N (δ(15)N plant - δ(15)N soil) to characterize nitrogen dynamics. In order to detect temporal trends, isotopic abundances in organic grasslands were related to the time since certification. Furthermore, discriminant analysis was used to test whether the respective management type can be deduced from observed isotopic abundances. Isotopic analyses revealed no significant differences in δ(13)C in hay and δ(15)N in both soil and hay between management types, but showed that δ(13)C abundances were significantly lower in soil of organic compared to conventional grasslands. Δδ(15)N values implied that management types did not substantially differ in nitrogen cycling. Only δ(13)C in soil and hay showed significant negative relationships with the time since certification. Thus, our result suggest that organic grasslands suffered less from drought stress compared to conventional grasslands most likely due to a benefit of higher plant species richness, as previously shown by manipulative biodiversity experiments. Finally, it was possible to correctly classify about two third of the samples according to their management using isotopic abundances in soil and hay. However, as more than half of the organic samples were incorrectly classified, we infer that more research is needed to improve this approach before it can be efficiently

  4. Organic vs. Conventional Grassland Management: Do 15N and 13C Isotopic Signatures of Hay and Soil Samples Differ?

    Science.gov (United States)

    Klaus, Valentin H.; Hölzel, Norbert; Prati, Daniel; Schmitt, Barbara; Schöning, Ingo; Schrumpf, Marion; Fischer, Markus; Kleinebecker, Till

    2013-01-01

    Distinguishing organic and conventional products is a major issue of food security and authenticity. Previous studies successfully used stable isotopes to separate organic and conventional products, but up to now, this approach was not tested for organic grassland hay and soil. Moreover, isotopic abundances could be a powerful tool to elucidate differences in ecosystem functioning and driving mechanisms of element cycling in organic and conventional management systems. Here, we studied the δ15N and δ13C isotopic composition of soil and hay samples of 21 organic and 34 conventional grasslands in two German regions. We also used Δδ15N (δ15N plant - δ15N soil) to characterize nitrogen dynamics. In order to detect temporal trends, isotopic abundances in organic grasslands were related to the time since certification. Furthermore, discriminant analysis was used to test whether the respective management type can be deduced from observed isotopic abundances. Isotopic analyses revealed no significant differences in δ13C in hay and δ15N in both soil and hay between management types, but showed that δ13C abundances were significantly lower in soil of organic compared to conventional grasslands. Δδ15N values implied that management types did not substantially differ in nitrogen cycling. Only δ13C in soil and hay showed significant negative relationships with the time since certification. Thus, our result suggest that organic grasslands suffered less from drought stress compared to conventional grasslands most likely due to a benefit of higher plant species richness, as previously shown by manipulative biodiversity experiments. Finally, it was possible to correctly classify about two third of the samples according to their management using isotopic abundances in soil and hay. However, as more than half of the organic samples were incorrectly classified, we infer that more research is needed to improve this approach before it can be efficiently used in practice

  5. Uptake and impact of vaccinating school age children against influenza during a season with circulation of drifted influenza A and B strains, England, 2014/15.

    Science.gov (United States)

    Pebody, Richard G; Green, Helen K; Andrews, Nick; Boddington, Nicola L; Zhao, Hongxin; Yonova, Ivelina; Ellis, Joanna; Steinberger, Sophia; Donati, Matthew; Elliot, Alex J; Hughes, Helen E; Pathirannehelage, Sameera; Mullett, David; Smith, Gillian E; de Lusignan, Simon; Zambon, Maria

    2015-01-01

    The 2014/15 influenza season was the second season of roll-out of a live attenuated influenza vaccine (LAIV) programme for healthy children in England. During this season, besides offering LAIV to all two to four year olds, several areas piloted vaccination of primary (4-11 years) and secondary (11-13 years) age children. Influenza A(H3N2) circulated, with strains genetically and antigenically distinct from the 2014/15 A(H3N2) vaccine strain, followed by a drifted B strain. We assessed the overall and indirect impact of vaccinating school age children, comparing cumulative disease incidence in targeted and non-targeted age groups in vaccine pilot to non-pilot areas. Uptake levels were 56.8% and 49.8% in primary and secondary school pilot areas respectively. In primary school age pilot areas, cumulative primary care influenza-like consultation, emergency department respiratory attendance, respiratory swab positivity, hospitalisation and excess respiratory mortality were consistently lower in targeted and non-targeted age groups, though less for adults and more severe end-points, compared with non-pilot areas. There was no significant reduction for excess all-cause mortality. Little impact was seen in secondary school age pilot only areas compared with non-pilot areas. Vaccination of healthy primary school age children resulted in population-level impact despite circulation of drifted A and B influenza strains.

  6. Students from UMass/Lowell Win $15,000 EPA Grant for Innovative Technology Project

    Science.gov (United States)

    A student research team from the University of Massachusetts in Lowell has been awarded $15,000 from the US Environmental Protection Agency to research a technology that would turn seafood shells and waste into fertilizer.

  7. Studies of the intermediary metabolism in cultured cells of the insect Spodoptera frugiperda using 13C- or 15N-labelled tracers

    Directory of Open Access Journals (Sweden)

    Bacher Adelbert

    2005-11-01

    Full Text Available Abstract Background Insect cells can serve as host systems for the recombinant expression of eukaryotic proteins. Using this platform, the controlled expression of 15N/13C labelled proteins requires the analysis of incorporation paths and rates of isotope-labelled precursors present in the medium into amino acids. For this purpose, Spodoptera frugiperda cells were grown in a complex medium containing [U-13C6]glucose. In a second experiment, cultures of S. frugiperda were grown in the presence of 15N-phenylalanine. Results Quantitative NMR analysis showed incorporation of the proffered [U-13C6]glucose into the ribose moiety of ribonucleosides (40 – 45% and into the amino acids, alanine (41%, glutamic acid/glutamine (C-4 and C-5, 30% and aspartate/asparagine (15%. Other amino acids and the purine ring of nucleosides were not formed from exogenous glucose in significant amounts (> 5%. Prior to the incorporation into protein the proffered 15N-phenylalanine lost about 70% of its label by transamination and the labelled compound was not converted into tyrosine to a significant extent. Conclusion Growth of S. frugiperda cells in the presence of [U-13C6]glucose is conducive to the fractional labelling of ribonucleosides, alanine, glutamic acid/glutamine and aspartic acid/asparagine. The isotopolog compositions of the ribonucleosides and of alanine indicate considerable recycling of carbohydrate intermediates in the reductive branch of the pentose phosphate pathway. The incorporation of 15N-labelled amino acids may be hampered by loss of the 15N-label by transamination.

  8. Investigating Student Use of Technology for Engaged Citizenship in A Global Age

    Directory of Open Access Journals (Sweden)

    Brad M. Maguth

    2012-05-01

    Full Text Available This study undertook a five month qualitative investigation into technology use amongst twelve high school social studies students in two different sites in the Midwestern United States. This study examined students’ use of technology and its relationship to three dimensions of citizenship in a global age: understand global events, issues, and perspectives, participate in global networks to communicate and collaborate with global audiences, and advocate on global problems and issues to think and act globally. Collecting data through semi-structured student interviews, online-threaded discussions and document analysis, I triangulated findings, and employed a qualitative approach. The study finds a relationship between student participants’ use of technology and their serving as engaged citizenship in a global age. In using technology, students accessed international news and information, joined global networks to communicate and collaborate with global audiences, and produced digital content for international audiences.

  9. Retrospective characterization of ontogenetic shifts in killer whale diets via δ13C and δ15N analysis of teeth

    Science.gov (United States)

    Newsome, Seth D.; Etnier, Michael A.; Monson, Daniel H.; Fogel, Marilyn L.

    2009-01-01

    Metabolically inert, accretionary structures such as the dentin growth layers in teeth provide a life history record of individual diet with near-annual resolution. We constructed ontogenetic δ13C and δ15N profiles by analyzing tooth dentin growth layers from 13 individual killer whales Orcinus orca collected in the eastern northeast Pacific Ocean between 1961 and 2003. The individuals sampled were 6 to 52 yr old, representing 2 ecotypes—resident and transient—collected across ~25° of latitude. The average isotopic values of transient individuals (n = 10) are consistent with a reliance on mammalian prey, while the average isotopic values of residents (n = 3) are consistent with piscivory. Regardless of ecotype, most individuals show a decrease in δ15N values of ~2.5‰ through the first 3 yr of life, roughly equivalent to a decrease of one trophic level. We interpret this as evidence of gradual weaning, after which, ontogenetic shifts in isotopic values are highly variable. A few individuals (n = 2) maintained relatively stable δ15N and δ13C values throughout the remainder of their lives, whereas δ15N values of most (n = 11) increased by ~1.5‰, suggestive of an ontogenetic increase in trophic level. Significant differences in mean δ13C and δ15N values among transients collected off California suggest that individuality in prey preferences may be prevalent within this ecotype. Our approach provides retrospective individual life history and dietary information that cannot be obtained through traditional field observations of free-ranging and elusive species such as killer whales, including unique historic ecological information that pre-dates modern studies. By providing insights into individual diet composition, stable isotope analysis of teeth and/or bones may be the only means of evaluating a number of hypothesized historical dietary shifts in killer whales of the northeast Pacific Ocean

  10. 15 CFR 19.13 - How will Commerce entities use administrative wage garnishment to collect a Commerce debt from a...

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false How will Commerce entities use administrative wage garnishment to collect a Commerce debt from a debtor's wages? 19.13 Section 19.13 Commerce and Foreign Trade Office of the Secretary of Commerce COMMERCE DEBT COLLECTION Procedures To Collect...

  11. Education of Social Skills among Senior High School Age Students in Physical Education Classes

    Science.gov (United States)

    Akelaitis, Arturas V.; Malinauskas, Romualdas K.

    2016-01-01

    Research aim was to reveal peculiarities of the education of social skills among senior high school age students in physical education classes. We hypothesized that after the end of the educational experiment the senior high school age students will have more developed social skills in physical education classes. Participants in the study were 51…

  12. The influence of fish cage culture on δ{sup 13}C and δ{sup 15}N of filter-feeding Bivalvia (Mollusca)

    Energy Technology Data Exchange (ETDEWEB)

    Benedito, E.; Takeda, A.M., E-mail: eva@nupelia.uem.br [Universidade Estadual de Maringa (UEM), PR (Brazil). Nucleo de Pesquisas em Limnologia, Ictiologia e Aquicultura; Figueroa, L. [Universidade Estadual de Maringa (UEM), PR (Brazil). Pos-Graduacao em Ecologia de Ambientes Aquaticos Continentais; Manetta, GI. [Universidade Estadual de Maringa (UEM), PR (Brazil). Pos-Graduacao em Biologia Comparada

    2013-11-15

    The objective of this study was to evaluate the effect of Oreochromis niloticus cage culture promoted variations in the δ{sup 13}C and δ{sup 15}N in Corbicula fluminea (Mollusca; Bivalvia) and in the sediment of an aquatic food web. Samples were taken before and after net cage installation in the Rosana Reservoir (Paranapanema River, PR-SP). Samples of specimens of the bivalve filter C. fluminea and samples of sediment were collected using a modified Petersen grab. All samples were dried in an oven (60 °C) for 72 hours, macerated to obtain homogenous fine powders and sent for carbon (δ{sup 13}C) and nitrogen (δ{sup 15}N) isotopic value analysis in a mass spectrometer. There were significant differences in the δ{sup 13}C and δ{sup 15}N values of the invertebrate C. fluminea between the beginning and the end of the experiment. There were no differences between the δ{sup 13}C and δ{sup 15}N values of sediment. These results indicate that the installation of fish cage culture promoted impacts in the isotopic composition of the aquatic food web organisms, which could exert influence over the native species and the ecosystem. (author)

  13. Evaluating the Superpave Option in Unified Facilities Guide Specification 32-12-15.13, Hot Mix Asphalt Airfield Paving

    Science.gov (United States)

    2014-06-01

    M249 5.47 2.291 2.381 3.8 12.8 70.6 5,132 18 M250 5.47 2.283 2.381 4.1 13.2 68.7 5,678 19 M251 5.47 2.287 2.381 4.0 13.0 69.4 5,534 16 M252 5.47...71 143.0 M250 5.47 1179.60 664.10 1180.7 0 516.60 2.28 2.38 4.12 13.15 68.70 142.48 M251 5.47 1158.4 652.3 1158.9 506.6 2.287 2.381 4.0 13.0 69

  14. Retinal nerve fiber layer thickness measured by optical coherence tomography in Chinese teenagers aged from 13 years old to 18 years old

    Directory of Open Access Journals (Sweden)

    Yu-Ming Zhang

    2014-04-01

    Full Text Available AIM: To establish a reference range of retinal nerve fiber layer(RNFLthickness by optical coherence tomography(OCTin Chinese teenagers aged from 13 to 18 years old, and investigate its relationship with age, eye side, gender, and ethnic group.METHODS: A total of 402 eyes from 201 normal Chinese aged from 13 to 18 years old were recruited for this study. Optic disk with 3.4mm diameter circle in different global average, quadrant and part-time bit retinal nerve fiber layer thickness(RNFLTwas measured by RNFL thickness average analysis program. Their RNFLT at different part-time bit, quadrant and global average RNFLT around the disc were measured by OCT with 3.4mm diameter circle, using the RNFL thickness average analysis program. The data was analyzed with SPSS statistical 19.0. The influences of several factors(such as age, eye side, gender, and ethnic groupon RNFLT were also analyzed.RESULTS: The global average RNFLT at 13, 14, 15, 16, 17, 18 years old was 108.32±9.42μm, 109.23±9.67μm, 110.36±11.14μm, 111.27±10.21μm, 109.23±9.67μm, 112.11±8.83μm respectively. RNFLT of right eyes was 109.82±8.93μm and of left eyes was 110.33±9.89μm. All of the male's average RNFLT was 110.14±10.02μm, and all of the female's average RNFLT was 109.96±11.22μm. The average RNFLT of Han nationality was 110.22±9.31μm and of non-Han nationality was 109.87±8.65μm. The average RNFLT of all was 110.02±9.87μm, the RNFLT at the superior, nasal, inferior and temporal quadrant was 146.56 ±18.88μm, 76.49±13.28μm, 136.64±16.29μm, 82.01±12.55μm respectively. There was no significant difference in gender, eye side, and ethnic group(all PCONCLUSION: This study has established a normal standard reference of RNFLT and its related indexes by OCT in Chinese teenagers aged 13-18 years old. Gender, age, eye side, and ethnic group have no effect on their RNFLT, which has significant difference with adult's data. And for the diagnosis and follow-up of

  15. Maternally Derived Microduplications at 15q11-q13: Implication of Imprinted Genes in Psychotic Illness

    DEFF Research Database (Denmark)

    Ingason, Andrés; Kirov, George; Giegling, Ina

    2011-01-01

    or schizoaffective disorder and 41,370 comparison subjects without known psychiatric illness for copy number variants at 15q11-q13 and determined the parental origin of duplications using methylation-sensitive Southern hybridization analysis. Results: Duplications were found in four case patients and five comparison...

  16. Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders.

    Directory of Open Access Journals (Sweden)

    Jerzy Wegiel

    Full Text Available It has been shown that amyloid ß (Aβ, a product of proteolytic cleavage of the amyloid β precursor protein (APP, accumulates in neuronal cytoplasm in non-affected individuals in a cell type-specific amount.In the present study, we found that the percentage of amyloid-positive neurons increases in subjects diagnosed with idiopathic autism and subjects diagnosed with duplication 15q11.2-q13 (dup15 and autism spectrum disorder (ASD. In spite of interindividual differences within each examined group, levels of intraneuronal Aβ load were significantly greater in the dup(15 autism group than in either the control or the idiopathic autism group in 11 of 12 examined regions (p<0.0001 for all comparisons; Kruskall-Wallis test. In eight regions, intraneuronal Aβ load differed significantly between idiopathic autism and control groups (p<0.0001. The intraneuronal Aβ was mainly N-terminally truncated. Increased intraneuronal accumulation of Aβ(17-40/42 in children and adults suggests a life-long enhancement of APP processing with α-secretase in autistic subjects. Aβ accumulation in neuronal endosomes, autophagic vacuoles, Lamp1-positive lysosomes and lipofuscin, as revealed by confocal microscopy, indicates that products of enhanced α-secretase processing accumulate in organelles involved in proteolysis and storage of metabolic remnants. Diffuse plaques containing Aβ(1-40/42 detected in three subjects with ASD, 39 to 52 years of age, suggest that there is an age-associated risk of alterations of APP processing with an intraneuronal accumulation of a short form of Aβ and an extracellular deposition of full-length Aβ in nonfibrillar plaques.The higher prevalence of excessive Aβ accumulation in neurons in individuals with early onset of intractable seizures, and with a high risk of sudden unexpected death in epilepsy in autistic subjects with dup(15 compared to subjects with idiopathic ASD, supports the concept of mechanistic and functional links

  17. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Françoise Benz

    2002-01-01

    Main Auditorium, bldg. 500   DATE TIME LECTURER TITLE Monday 5 August 09:15-10:00 F. GIANOTTI LHC Physics (1/3) 10:15-12:00 T. NAKADA CP Violation (3&4/4) Tuesday 6 August 09:15-10:00 F. GIANOTTI LHC Physics (2/3) 10:15-11:00 R. JACOBSEN From Raw Data to Physics Results (1/3) 11:15-12:00 R. JACOBSEN / T. NAKADA Discussion Session Wednesday 7 August 09:15-10:00 F. GIANOTTI LHC Physics (3/3) 10:15-11:00 R. JACOBSEN From Raw Data to Physics Results (2/3) 11:15-12:00 J. LESGOURDES Cosmology (1/4) 14:00-16:00 C. BENVENUTI Basic Science, Society, and Technological Innovation (Council Chamber, bldg. 503) Thursday 8 August 09:15-10:00 J. LESGOURDES Cosmology (2/4) 10:15-11:00 R. JACOBSEN From Raw Data to Physics Results (3/3) 11:15-12:00 J. CARR / J. LESGOURDES Discussion Session Friday 9 August 09:15-11:00 J. LESGOURDES Cosmology (3&4/4) 11:15-12:00 C. JARLSKOG Historic Lecture 14:00-16:00 Course Review Monday 12 August 09:15-12:00 Students Sessi...

  18. Group-13 and group-15 doping of germanane

    Directory of Open Access Journals (Sweden)

    Nicholas D. Cultrara

    2017-08-01

    Full Text Available Germanane, a hydrogen-terminated graphane analogue of germanium has generated interest as a potential 2D electronic material. However, the incorporation and retention of extrinsic dopant atoms in the lattice, to tune the electronic properties, remains a significant challenge. Here, we show that the group-13 element Ga and the group-15 element As, can be successfully doped into a precursor CaGe2 phase, and remain intact in the lattice after the topotactic deintercalation, using HCl, to form GeH. After deintercalation, a maximum of 1.1% As and 2.3% Ga can be substituted into the germanium lattice. Electronic transport properties of single flakes show that incorporation of dopants leads to a reduction of resistance of more than three orders of magnitude in H2O-containing atmosphere after As doping. After doping with Ga, the reduction is more than six orders of magnitude, but with significant hysteretic behavior, indicative of water-activation of dopants on the surface. Only Ga-doped germanane remains activated under vacuum, and also exhibits minimal hysteretic behavior while the sheet resistance is reduced by more than four orders of magnitude. These Ga- and As-doped germanane materials start to oxidize after one to four days in ambient atmosphere. Overall, this work demonstrates that extrinsic doping with Ga is a viable pathway towards accessing stable electronic behavior in graphane analogues of germanium.

  19. Photoluminescence quenching by OH in Er- and Pr-doped glasses for 1.5 and 1.3 μm optical amplifiers

    Science.gov (United States)

    Faber, Anne J.; Simons, Dennis R.; Yan, Yingchao; de Waal, Henk

    1994-09-01

    In this paper we report on the effect of hydroxyl (OH) groups on the photoluminescence in the near IR (1.5 and 1.3 micrometers ) in rare earth (Er, Pr)-doped glasses. The 1.5 micrometers emission of Er-doped phosphate glasses was studied, before and after a special heat treatment. The luminescent lifetime of the 1.5 micrometers emission increases substantially, typically from 3 ms up to 7.2 ms for a 2 mole% Er2O3-doped phosphate glass, due to the controlled heat treatment. The increase in lifetime is ascribed to a decrease in OH- concentration, which is confirmed by IR-absorption spectroscopy. The quenching by OH is described by a simplified quenching model, which predicts the 1.5 micrometers emission lifetime as a function of Er- concentration with the OH-concentration as parameter. It appears that the larger part of the OH groups is coupled to Er ions and thus acts as quenching center. Photoluminescence quenching by OH groups is also reported for the 1.3 micrometers emission of Pr in GeS2-glasses: In pure OH-free GeS2 glass the 1.3 micrometers emission lifetime is as high as 350 microsecond(s) , for a 400 ppm dopant level. In GeS2 glasses containing only small amounts of OH (approximately 100 ppm), this lifetime is less than 200 microsecond(s) . Both examples demonstrate that for the fabrication of efficient glass optical amplifiers at the telecommunication windows 1.3 and 1.5 micrometers , the OH-impurity level of the host glass must be kept as low as possible.

  20. Ab initio/GIAO-CCSD(T) (13)C NMR study of the rearrangement and dynamic aspects of rapidly equilibrating tertiary carbocations, C6H13(+) and C7H15(+).

    Science.gov (United States)

    Olah, George A; Prakash, G K Surya; Rasul, Golam

    2016-01-05

    The rearrangement pathways of the equilibrating tertiary carbocations, 2,3-dimethyl-2-butyl cation (C6H13(+), 1), 2,3,3-trimethyl-2-butyl cation (C7H15(+), 5) and 2,3-dimethyl-2-pentyl cation (C7H15(+), 8 and 9) were investigated using the ab initio/GIAO-CCSD(T) (13)C NMR method. Comparing the calculated and experimental (13)C NMR chemical shifts of a series of carbocations indicates that excellent prediction of δ(13)C could be achieved through scaling. In the case of symmetrical equilibrating cations (1 and 5) the Wagner-Meerwein 1,2-hydride and 1,2-methide shifts, respectively, produce the same structure. This indicates that the overall (13)C NMR chemical shifts are conserved and independent of temperature. However, in the case of unsymmetrical equilibrating cations (8 and 9) the Wagner-Meerwein shift produces different tertiary structures, which have slightly different thermodynamic stabilities and, thus, different spectra. At the MP4(SDTQ)/cc-pVTZ//MP2/cc-pVTZ + ZPE level structure 8 is only 90 calories/mol more stable than structure 9. Based on computed (13)C NMR chemical shift calculations, mole fractions of these isomers were determined by assuming the observed chemical shifts are due to the weighted average of the chemical shifts of the static ions. © 2015 Wiley Periodicals, Inc.

  1. The prevalence of Non-suicidal Self-Injury (NSSI) among high school students in relation to age and sex.

    Science.gov (United States)

    Kądziela-Olech, Halina; Zak, Gabriel; Kalinowska, Barbara; Wągrocka, Anna; Perestret, Grzegorz; Bielawski, Michał

    2015-01-01

    The undertaken research aimed at determining the frequency of deliberate self-injurious behaviour (D-SIB) among the students of secondary schools and also the analysis of the frequency of repeated Non-Suicidal Self-Injury (NSSI) occurrences in accordance with DSM-5 criteria in reference to the age and sex in the studied population. The data was collected via survey method according to the questionnaire prepared in compliance with the criteria DSM-5 and Self-Harm Inventory. The study included randomly selected students: 1193 boys and 1027 girls in Bialystok aged 12 and 19 (average age ± SD:16.8 ± 1.65). Statistical analysis of the data was carried out using the application Statistica 10.0 PL, StatSoft. These results indicate that D-SIB and NSSI affect both sexes. In the studied group 8.3 % of students engage in deliberate self-injurious behaviour. The percentage of NSSI was 4.8% (6.3% in the group of boys, 3.2 % among girls; p(Chi2)=0.01). Self-cutting was most common among 15-year-old pupils ((D-SIB:14.75%; NNSI:8.1%). The majority of respondents (82% of girls and 74% of boys) revealed that as a result of self-injury behaviour they experience relief. Conducting further research in the area of NSSI seems to be crucial due to chronicity and prevalence as well as the fact that numerous repeated self-injuries bringing relief or causing positive state of mind might indicate a mechanism similar to an addiction syndrome in adolescence.

  2. Tobacco use among students in Bihar (India).

    Science.gov (United States)

    Sinha, Dhirendra N; Gupta, Prakash C; Pednekar, Mangesh

    2004-01-01

    Determination of the prevalence and attitudes toward tobacco use was assessed among 13-15 years school students in Bihar (India). Schools having grade 8-10 in Bihar. A two stage cluster sample design was used. SUDAAN and the C-sample procedure in Epi-Info was used for statistical analysis. Of the 2636 respondents, 71.8% (76.5% boys, 57.2% girls) were ever tobacco users; of them 48.9% had used tobacco before 10 years of age. Current use was reported by 58.9% (Boys 61.4%, Girls 51.2%); smokeless tobacco by 55.6% (Boys 57.6%, Girls 49.2%); and smoking by 19.4% (23.0% boys, 7.8% girls). Nearly one third (29%) students were exposed to ETS inside their homes and nearly half (48%) outside their homes. Almost all students reported watching cigarette and gutka advertisements in almost all kinds of media and events. Tobacco use by parents and friends, knowledge on harmful effects of chewing tobacco, smoking and environmental smoke, and attitudes on tobacco use by others were strongly associated with student tobacco use. Current tobacco use was reported significantly more by students who received pocket money/or were earning than by students who did not receive any pocket money/or did not earn (p value for trend <0.0001). Over half of current users (56%) bought their tobacco products from stores; of these, over 3/4th (77.2%) of them despite their age, had no difficulty in procuring these products. Teaching in schools regarding harmful effects of tobacco use was non-existent (3%). This urgently requires a comprehensive prevention program in schools and the community especially targeted towards girls.

  3. Needle-Age Related Variability in Nitrogen, Mobile Carbohydrates, and δ13C within Pinus koraiensis Tree Crowns

    Science.gov (United States)

    Yan, Cai-Feng; Han, Shi-Jie; Zhou, Yu-Mei; Wang, Cun-Guo; Dai, Guan-Hua; Xiao, Wen-Fa; Li, Mai-He

    2012-01-01

    For both ecologists and physiologists, foliar physioecology as a function of spatially and temporally variable environmental factors such as sunlight exposure within a tree crown is important for understanding whole tree physiology and for predicting ecosystem carbon balance and productivity. Hence, we studied concentrations of nitrogen (N), non-structural carbohydrates (NSC = soluble sugars + starch), and δ13C in different-aged needles within Pinus koraiensis tree crowns, to understand the needle age- and crown position-related physiology, in order to test the hypothesis that concentrations of N, NSC, and δ13C are needle-age and crown position dependent (more light, more photosynthesis affecting N, NSC, and δ13C), and to develop an accurate sampling strategy. The present study indicated that the 1-yr-old needles had significantly higher concentration levels of mobile carbohydrates (both on a mass and an area basis) and Narea (on an area basis), as well as NSC-N ratios, but significantly lower levels of Nmass (on a mass basis) concentration and specific leaf area (SLA), compared to the current-year needles. Azimuthal (south-facing vs. north-facing crown side) effects were found to be significant on starch [both on a mass (STmass) and an area basis (STarea)], δ13C values, and Narea, with higher levels in needles on the S-facing crown side than the N-facing crown side. Needle Nmass concentrations significantly decreased but needle STmass, STarea, and δ13C values significantly increased with increasing vertical crown levels. Our results suggest that the sun-exposed crown position related to photosynthetic activity and water availability affects starch accumulation and carbon isotope discrimination. Needle age associated with physiological activity plays an important role in determining carbon and nitrogen physiology. The present study indicates that across-scale sampling needs to carefully select tissue samples with equal age from a comparable crown position

  4. Curiosity killed the cat: no evidence of an association between cat ownership and psychotic symptoms at ages 13 and 18 years in a UK general population cohort.

    Science.gov (United States)

    Solmi, F; Hayes, J F; Lewis, G; Kirkbride, J B

    2017-07-01

    Congenital or early life infection with Toxoplasma gondii has been implicated in schizophrenia aetiology. Childhood cat ownership has been hypothesized as an intermediary marker of T. gondii infection and, by proxy, as a risk factor for later psychosis. Evidence supporting this hypothesis is, however, limited. We used birth cohort data from the Avon Longitudinal Study of Parents and Children (ALSPAC) to investigate whether cat ownership in pregnancy and childhood (ages 4 and 10 years) was associated with psychotic experiences (PEs) in early (age 13, N = 6705) and late (age 18, N = 4676) adolescence, rated from semi-structured interviews. We used logistic regression to examine associations between cat ownership and PEs, adjusting for several sociodemographic and socioeconomic factors, household characteristics and dog ownership. Missing data were handled via multiple imputation. Cat ownership during pregnancy was not associated with PEs at age 13 years [adjusted odds ratio (OR) 1.15, 95% confidence interval (CI) 0.97-1.35] or 18 years (OR 1.08, 95% CI 0.86-1.35). Initial univariable evidence that cat ownership at ages 4 and 10 years was associated with PEs at age 13 years did not persist after multivariable adjustment (4 years: OR 1.18, 95% CI 0.94-1.48; 10 years: OR 1.12, 95% CI 0.92-1.36). There was no evidence that childhood cat ownership was associated with PEs at age 18 years. While pregnant women should continue to avoid handling soiled cat litter, given possible T. gondii exposure, our study strongly indicates that cat ownership in pregnancy or early childhood does not confer an increased risk of later adolescent PEs.

  5. Predictors of influenza vaccination in the U.S. among children 9-13years of age.

    Science.gov (United States)

    Imburgia, Teresa M; Hendrix, Kristin S; Donahue, Kelly L; Sturm, Lynne A; Zimet, Gregory D

    2017-04-25

    U.S. estimates of seasonal influenza (flu) vaccine uptake in 2014-2015 were 62% for 5-12year olds, dropping to 47% for 13-17year olds. The Healthy People 2020 goal for these age groups is 80%. It is important to understand factors associated with influenza vaccination, especially for those ages where rates begin to decline. The objective of this study was to identify factors associated with influenza vaccination acceptance in 9-13year old children. An online U.S. survey of mothers of children aged 9-13 assessed children's influenza vaccine uptake in the previous season, healthcare utilization, sociodemographics, and vaccine attitudes. Multivariable logistic regression identified independent predictors of influenza vaccine status. There were 2363 respondents (Mean age=38years old). Referent children were 57% female and 66% non-minority race/ethnicity with a mean age of 10.6years. By maternal report, 59% of children had received an influenza vaccine in the previous season. Predictors of influenza vaccine uptake included a recommendation or strong recommendation from a health care provider, seeing a health care provider in the past year, positive attitudes regarding the influenza vaccine, and being a minority race. Child gender, age, insurance coverage, and whether the child had a regular healthcare provider were not associated with influenza vaccine uptake (p=n.s.). This sample reported overall rates of influenza vaccine uptake similar to national surveillance data, but still lower than national goals. Provider recommendations along with health attitudes and seeing a health care provider were associated with vaccine uptake. Promising interventions may include more directive physician messaging for influenza vaccine uptake in youth, encouraging more regular well-child visits during the adolescent years, and promoting influenza vaccination at alternative sites. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Differences and similarities in sexual and contraceptive knowledge, attitudes, and behavior among Latino male adolescent students in California, United States and Lima, Peru

    Directory of Open Access Journals (Sweden)

    Chirinos Jesús L.

    2001-01-01

    Full Text Available To identify the differences and similarities in sexual and contraceptive knowledge, attitudes, and behavior among Latino male adolescent students living in California and Lima. Self-administered, anonymous surveys were completed by Latino male students aged 12-19 participating in California, and by male adolescent students in four high schools in Lima. Both surveys contained similar questions allowing for comparisons regarding sexual activity and contraceptive behavior. The mean age of male students were 16 and 15 years, respectively. More California males reported having engaged in sexual intercourse (69% vs 43%. The sexual debut was 13 years in both samples. More students in California were aware of their risk of pregnancy at first sexual intercourse than in Lima (82% vs 50%. One-third of the California males reported communicating with their partner about sex and contraception to be "easy" as compared to 53% of males in Lima. More students in California reported knowing a place to obtain contraceptives if they need them (85% vs 63%, having ever gotten someone pregnant (29% vs 7%, and having fathered a child (67% vs 16%.

  7. Students-exhibits interaction at a science center

    Science.gov (United States)

    Botelho, Agostinho; Morais, Ana M.

    2006-12-01

    In this study we investigate students' learning during their interaction with two exhibits at a science center. Specifically, we analyze both students' procedures when interacting with exhibits and their understanding of the scientific concepts presented therein. Bernstein's theory of pedagogic discourse (1990, 2000) provided the sociological foundation to assess the exhibit-student interaction and allowed analysis of the influence of the characteristics of students, exhibits, and interactions on students' learning. Eight students (ages 12ndash;13 years of age) with distinct sociological characteristics participated in the study. Several findings emerged from the results. First, the characteristics of the students, exhibits, and interactions appeared to influence student learning. Second, to most students, what they did interactively (procedures) seems not to have had any direct consequence on what they learned (concept understanding). Third, the data analysis suggest an important role for designers and teachers in overcoming the limitations of exhibit-student interaction.

  8. Effect of short-term research training programs on medical students' attitudes toward aging.

    Science.gov (United States)

    Jeste, Dilip V; Avanzino, Julie; Depp, Colin A; Gawronska, Maja; Tu, Xin; Sewell, Daniel D; Huege, Steven F

    2018-01-01

    Strategies to build a larger workforce of physicians dedicated to research on aging are needed. One method to address this shortage of physician scientists in geriatrics is short-term training in aging research for early-stage medical students. The authors examined the effects of two summer research training programs, funded by the National Institutes of Health, on medical students' attitudes toward aging, using the Carolina Opinions on Care of Older Adults (COCOA). The programs combined mentored research, didactics, and some clinical exposure. In a sample of 134 participants, COCOA scores improved significantly after completion of the research training program. There was a significant interaction of gender, such that female students had higher baseline scores than males, but this gender difference in COCOA scores was attenuated following the program. Four of the six COCOA subscales showed significant improvement from baseline: early interest in geriatrics, empathy/compassion, attitudes toward geriatrics careers, and ageism.

  9. Attitude toward Christianity and paranormal belief among 13- to 16-yr.-old students.

    Science.gov (United States)

    Williams, Emyr; Francis, Leslie J; Robbins, Mandy

    2006-08-01

    A small but statistically significant positive correlation (r = .17) was found in a sample of 279 13- to 16-yr.-old students in Wales between scores on the Francis Scale of Attitude toward Christianity and on a new Index of Paranormal Belief. These data suggest that there is little common variance between attitude toward Christianity and belief in the paranormal.

  10. Comparing the Prevalence of Handedness between Normal and Congenitally Deaf Students in Age Intervals of 12 to 18 Years in Tehran

    Directory of Open Access Journals (Sweden)

    Zahra Jafari

    2007-04-01

    Full Text Available Objective: Handedness is the most prominent behavioral asymmetry in human. The term of hand preference points to prefer hand or functional asymmetry in manual tasks. The items were considered in this study were: the comparison of handedness between normal and congenitally deaf students the effects of age, sex, and pressure on using right hand for unimanual tasks on handedness the frequency of left-handers among student’s families, the influence of hand preference on English language capabilities, and the point of view of people rather to left-handers have been investigated. Materials & Methods: This cross-sectional comparative study was conducted on 760 students including 380 normal students and 380 deaf students with congenital severe or profound sensory-neural hearing loss from 12 to 18 years of age by that were selected purposefully, completing Edinburg handedness inventory in Tehran. The students didn’t have any confirmed diseases or neurological disorders, except hearing loss in deaf student. Data were gathered through the completion of the Edinburg Handedness Inventory by the students. The student’s aural records and also the confirmation of the audiologist in the deaf schools were considered in order to determine the kind and degree of hearing loss. Results: The prevalence of left-handedness among normal (9.7% and deaf (10.3% students were near to each other, and there was no significant difference between them (P=0.901, z=-1.24. The prevalence of left-handedness was higher in boys rather than girls, but there was no significant influence of sex and age on results (P>0.05. The family and/or teacher pressure for using right hand was 16.0% in normal students and 5.0% in deaf students, and they didn’t report any strict pressure or severity regard this mater. The frequency of left-handers was higher among family of normal students (22.6% than deaf students (13.2%, and the difference between them was significant statistically (P=0

  11. A Self-Instructional Course in Student Financial Aid Administration. Module 13: Verification. Second Edition.

    Science.gov (United States)

    Washington Consulting Group, Inc., Washington, DC.

    Module 13 of the 17-module self-instructional course on student financial aid administration (designed for novice financial aid administrators and other institutional personnel) focuses on the verification procedure for checking the accuracy of applicant data used in making financial aid awards. The full course provides an introduction to the…

  12. 12/15 lipoxygenase regulation of colorectal tumorigenesis is determined by the relative tumor levels of its metabolite 12-HETE and 13-HODE in animal models

    OpenAIRE

    Chang, Jian; Jiang, Li; Wang, Yinqiu; Yao, Bing; Yang, Shilin; Zhang, Bixiang; Zhang, Ming-Zhi

    2014-01-01

    Colorectal cancer (CRC) continues to be a major cause of morbidity and mortality. The arachidonic acid (AA) pathway and linoleic acid (LA) pathway have been implicated as important contributors to CRC development and growth. Human 15-lipoxygenase 1 (15-LOX-1) converts LA to anti-tumor 13-S-hydroxyoctadecadienoic acid (13-HODE)and 15-LOX-2 converts AA to 15-hydroxyeicosatetraenoic acid (15-HETE). In addition, human 12-LOX metabolizes AA to pro-tumor 12-HETE. In rodents, the function of 12-LOX ...

  13. Cyberstalking and College-Age Students: A Bibliometric Analysis across Scholarly Databases

    Science.gov (United States)

    Piotrowski, Chris; Lathrop, Peter J.

    2012-01-01

    Research on the topic of cyberbullying has proliferated over the past decade, particularly on its impact on school-aged children (see Piotrowski, 2011). However, there is limited research on the incidence and impact of cyberstalking, a related type of cyber-abuse, on college-age students. Thus, it would be of interest to examine the extent of…

  14. Comparison of nutritional status of rural and urban school students receiving midday meals in schools of Bengaluru, India: A cross sectional study

    Directory of Open Access Journals (Sweden)

    C N Shalini

    2014-01-01

    Full Text Available Background: The objective of the study was to assess the impact of the mid day meal program by assessing the nutritional status of school students aged 5-15 years receiving midday meals in rural schools and compare them with those in urban schools in Bengaluru, India. Materials and Methods: This cross sectional study involved a sample of 4378 students from government and aided schools. Weight and height were measured and compared with ′′means′′ and ′′percentiles′′ of expected standards as endorsed by the Indian Association of Pediatrics. Regression coefficients were also estimated to assess the rate of growth. Results: In all age groups and in both sexes, the observed mean weight and height were below the expected standards. The study findings showed that 13.8% and 13.1% of the studied students were underweight and stunted, respectively (below the third percentile for weight and height for age. A higher proportion of rural students were below the third percentile for both weight and height compared with urban students (weight: 16.3% and 11.5%; height: 17.0% and 10.0%; P < 0.05 for both weight and height. Only 2.4% and 3.1% were above 97 th percentile for weight and height. The rate of growth of height for weight showed a declining trend with increasing age in all the groups. Discussion: The authors believe that the magnitude of the burden of undernourished students as seen in this study would have been much greater in the absence of the midday meal program. Conclusion: Greater involvement of the private sector to assist the government would help augment nutrition in children and indirectly impact school performance, attendance and literacy.

  15. Age of M92 and M15

    International Nuclear Information System (INIS)

    Sandage, A.

    1983-01-01

    Comparison of VandenBerg's isochrones for globular clusters with the photometry of many main-sequence stars in M92 and M15 gives an age of T = 18 +- 2 x 10 9 years for both clusters, using a vertical fit to the turn-off luminosity, together with distance modulii found from the period-color-luminosity relation of their RR Lyrae stars. Comparison of the systematics of the composite CM diagram for clusters of different metallicity with that predicted from VandenBerg's isochrones, all for T = 18 x 10 9 years, shows good agreement. Justification of the adopted zero-point value of M/sub v/ (RR,M92) = +0.63 is made by comparing the main sequences of M92, M3, and M5 with that defined by 11 field subdwarfs whose metallicities lie between [Fe/H] of -2.2 and -1.2 for which adequate astrometric distances exist

  16. Socio-motivational moderators – Two sides of the same coin?Testing the potential buffering role of socio-motivational relationships on achievement drive and test anxiety among German and Canadian secondary school students

    Directory of Open Access Journals (Sweden)

    Frances eHoferichter

    2015-10-01

    Full Text Available The current cross-national study investigates the potential buffering role of socio-motivational relationships for the association of achievement drive and test anxiety in secondary school students from Canada and Germany. One thousand eighty-eight students (54% girls, Mage = 13.71, SD = .53, age span 12–15 years from the state of Brandenburg and 389 students from Quebéc (55.9% girls, Mage = 13.43, SD = .82, age span 12–16 years were asked about their socio-motivational relationships with their teachers and peers, their drive for achievement, and test anxiety. Multigroup latent moderated structural equations (MGLMS were conducted to test for the moderator role of socio-motivational relationships that would buffer feelings of test anxiety related to the drive for achievement. The analyses revealed the two-sided role socio-motivational relationships can have for students with different levels of achievement drive; intensifying or mitigating feelings of test anxiety. Thereby, the results of this study extend the buffering hypothesis by Cohen and Wills (1985. Cross-national differences between Canada and Germany were found concerning the studied moderators on the association of achievement drive and test anxiety: While for German students teacher-student relationships acted as moderator, for Canadian students student-student relationships and teachers acting as positive motivators displayed a moderator role.

  17. Experiencing aging or demystifying myths? - impact of different "geriatrics and gerontology" teaching strategies in first year medical students.

    Science.gov (United States)

    Lucchetti, Alessandra Lamas Granero; Lucchetti, Giancarlo; de Oliveira, Isabella Noceli; Moreira-Almeida, Alexander; da Silva Ezequiel, Oscarina

    2017-02-08

    With the aging of the population comes a greater need for geriatric and gerontology teaching. However, there is currently a dearth of investigations on the impact of different educational methodologies for teaching in this area early in medical courses. The present study aims to determine the impact of two educational strategies on the topic "Geriatrics and Gerontology" ("experiencing aging" and "myths of aging") as compared to a control group (no intervention) on the attitudes, empathy and knowledge of first year medical students. An intervention-based study in education was conducted at the beginning of the first year of a medical course. Students submitted to educational strategies were compared against students with no intervention. The two strategies were: "Experiencing Aging" - also known as the "aging game" (simulation of the disabilities and physiological changes of aging), and "Myths of Aging" - a knowledge discussion based on a "quiz show", questioning common myths about aging. All students were assessed on their attitudes towards older persons (Maxwell-Sullivan, UCLA attitudes), empathy (Maxwell-Sullivan), knowledge on facts and positive view about aging (Palmore), and cognitive knowledge. Data were analysed using Student's t, Chi-squared or ANOVA tests. A total of 230 students were assessed. The "experiencing aging" intervention was associated with improvement in empathy but worsening of attitude. The "myths of aging" intervention was associated with an improved attitude overall and positive view about aging but with no change in empathy towards older persons. Educational strategies can influence the attitudes and empathy of students, leading to different outcomes. These data highlight the importance of assessing the outcomes of educational strategies in medical teaching to ascertain in what manner (how), situations (when) and settings (where) these activities should be introduced.

  18. Validity Evidence for a Chinese Version of the Online Self-Regulated Learning Questionnaire with Average Students and Mathematically Talented Students

    Science.gov (United States)

    Fung, Joyce J. Y.; Yuen, Mantak; Yuen, Allan H. K.

    2018-01-01

    A Chinese version of the Online Self-Regulated Learning Questionnaire (OLSQ) was administered to 412 Hong Kong students of average ability and 374 students talented in mathematics (Grades 4-9, age 9-15 years). Data indicated that the Chinese OLSQ provides valid and reliable scores when used with these students.

  19. Thalassaemia screening among students in a secondary school in Ampang, Malaysia.

    Science.gov (United States)

    Jameela, S; Sabirah, S O Sharifah; Babam, J; Phan, C L; Visalachy, P; Chang, K M; Salwana, M A; Zuraidah, A; Subramanian, Y; Rahimah, A

    2011-12-01

    Thalassaemia is a common disorder in Malaysia. It is estimated that 4.5% of the population are carriers for beta- or alpha- thalassaemias. We set out to screen Form 4 students aged between 15 and 16 years old in a national school, for thalassaemia in March 2008. Written consent was obtained from 310 students. The carrier rate for the common thalassaemia syndromes was 6.8% (2.9% for beta-thalassaemia, 2.6% for HbE and 1.3% for two-gene deletion for alpha-thalassaemia). Carriers for beta-thalassaemia and two-gene deletion for alpha-thalassaemia were more common in the Chinese (4.3% and 1.4% respectively) while heterozygous HbE was more common in the Malays (3.8%). The laboratory cost of screening one student was RM 45 and the total number of man-hours spent in this screening activity was 600. This screening exercise showed that thalassaemia carriers are common among the Chinese and Malays and it is feasible to carry out a screening programme for secondary school students.

  20. The relationship of gross upper and lower limb motor competence to measures of health and fitness in adolescents aged 13-14 years.

    Science.gov (United States)

    Weedon, Benjamin David; Liu, Francesca; Mahmoud, Wala; Metz, Renske; Beunder, Kyle; Delextrat, Anne; Morris, Martyn G; Esser, Patrick; Collett, Johnny; Meaney, Andy; Howells, Ken; Dawes, Helen

    2018-01-01

    Motor competence (MC) is an important factor in the development of health and fitness in adolescence. This cross-sectional study aims to explore the distribution of MC across school students aged 13-14 years old and the extent of the relationship of MC to measures of health and fitness across genders. A total of 718 participants were tested from three different schools in the UK, 311 girls and 407 boys (aged 13-14 years), pairwise deletion for correlation variables reduced this to 555 (245 girls, 310 boys). Assessments consisted of body mass index, aerobic capacity, anaerobic power, and upper limb and lower limb MC. The distribution of MC and the strength of the relationships between MC and health/fitness measures were explored. Girls performed lower for MC and health/fitness measures compared with boys. Both measures of MC showed a normal distribution and a significant linear relationship of MC to all health and fitness measures for boys, girls and combined genders. A stronger relationship was reported for upper limb MC and aerobic capacity when compared with lower limb MC and aerobic capacity in boys (t=-2.21, degrees of freedom=307, P=0.03, 95% CI -0.253 to -0.011). Normally distributed measures of upper and lower limb MC are linearly related to health and fitness measures in adolescents in a UK sample. NCT02517333.

  1. Do Parents’ Exercise Habits Predict 13–18-Year-Old Adolescents’ Involvement in Sport?

    Directory of Open Access Journals (Sweden)

    Saulius Sukys, Daiva Majauskienė, Vida J. Cesnaitiene, Diana Karanauskiene

    2014-09-01

    Full Text Available This study examined links between parents’ exercise habits and adolescents’ participation in sports activities, considering the aspects of gender and age. It was hypothesized that regular exercise by both parents would be related to children’s involvement in sport regardless of their gender and age. Moreover, it was hypothesized that children’s sports activities would be more strongly related to their father’s exercise activities. The study also examined the links between parents’ exercise habits and children’s motivation for sports. It was hypothesized that competition motives would be more important for children whose parents exercised regularly. The research sample included 2335 students from the seventh (n = 857, ninth (n = 960 and eleventh (n = 518 grades of various Lithuanian schools. The study used a questionnaire survey method, which revealed the links between parents’ exercise habits and their children’s participation in sport. Assessment of data for girls and boys showed that daughters’ participation in sport could be predicted by both their fathers’ and mothers’ exercise habits, but sons’ sports activities could be predicted only by the regular physical activities of their fathers. The assessment of children’s sporting activities according to age revealed links between parental exercising and the engagement of older (15–16 years old, but not younger adolescents (13–14 years old. Analysis of sports motivation showed that competition motives were more important for boys than for girls. Fitness, well-being and appearance motives were more important for older adolescents (15–18 years old, while competition motives were more important for younger adolescents (13–14 years old. Research revealed the relationship between children’s sport motives and fathers’ exercise habits, while examination of mothers’ exercise revealed no difference.

  2. Contribution of diet to δ15N, δ13C, and Δ14C values in the Pacific rat (Rattus exulans)

    International Nuclear Information System (INIS)

    Beavan, N.R.

    2001-01-01

    This thesis is the outcome of a research project undertaken to determine how diet can affect the reliability of rat bone (especially that of Rattus exulans) for accurate radiocarbon analysis. It addresses questions about the reliability of R. exulans bone for radiocarbon dating with respect to the survival of bone in archaeological and natural burial sites, laboratory processing methods, and the extent to which diet influences radiocarbon ages of bone. I have shown that R. exulans bone can return reliable radiocarbon dates, based on bone survival and the efficacy of chemical treatment to remove burial contamination. In three dietary investigations, stable isotope (δ 13 C and δ 15 N) and radiocarbon ( 14 C) analyses of modern populations and archaeological specimens also indicated that Rattus exulans and other omnivorous species can have radiocarbon values influenced by a diet linked to 14 C - depleted reservoirs. Moreover, depleted carbon reservoir effects are localised and variable in their magnitude. Work on modern populations also provided an improved means of isotopic analysis in an ecological study, where bomb-generated radiocarbon (Δ 14 C) signatures in the natural environment were used as for other 'tracer' studies, in conjunction with stable isotopes (δ 13 C and δ 15 N). Results indicated that the changing atmospheric 14 C signal fixed into the biota in a given year by photosynthesis is transferred from plants through trophic levels to end-members, including rats. The additional isotopic 'clue' about diet given by radiocarbon analysis offered a better understanding of the variation in diets of R. exulans in different habitats. Variation in the isotopic signal among individuals supported other observations that diets of scavenging rats are opportunistic and associated with faunal availability in different habitats. To better understand diet-induced radiocarbon variations, I also examined the carbon contribution to bone protein from essential amino acids

  3. A Survey on Mental Health Status of Adult Population Aged 15 and above in the Province of Golestan, Iran.

    Science.gov (United States)

    Noorbala, Ahmad Ali; Bagheri Yazdi, Seyed Abbas; Faghihzadeh, Soghrat; Kamali, Koorosh; Faghihzadeh, Elham; Hajebi, Ahmad; Akhondzadeh, Shahin; Shakiba, Alia; Hashemi Nasab, Seyedeh Maryam

    2017-11-01

    This research aims to determine the mental health status of population aged 15 and over in the province of Golestan in 2015. The statistical population of this cross-sectional field survey consisted of residents of urban and rural areas of Golestan province in Iran. An estimated sample size of 1200 people was chosen using systematic random cluster sampling. The access was provided by the contribution of Geographical Post Office of Gorgan, Gonbad-e-Qabus, and Aqqala cities. The General Health Questionnaire-28 (GHQ-28) was used as the screening tool for mental disorders. The analysis of data in the current study was carried out using the SPSS-18 computer software. Using GHQ traditional scoring method, the results showed that 12.8% of the subjects showed to be at risk of mental disorders (13.3% of females and 12.3% of males). Urban areas (13%) were more at risk of mental disorders compared with rural residents (12.3%). Anxiety and somatization symptoms were more frequent than depression and social dysfunction among respondents. The obtained data revealed that the prevalence of mental disorders increased with age. The results also indicated that mental disorders were more common in certain subgroups, in particular women, those aged 65 years and above, the divorced and widowed, illiterate and retired adults. Our findings suggest that one eighth of the participants were at risk of developing mental disorders. Although the prevalence of these disorders has decreased from 39.1% to 12.8% between 1999 and 2015, it is still of great importance to further promote mental health policies and advocate psychological welfare of those suffering from mental disorders along with their re-empowerment.

  4. Factors associated with HIV/AIDS sexual risk among young women aged 15-24 years in Nigeria

    Directory of Open Access Journals (Sweden)

    Chinekwu A. Obidoa

    2012-03-01

    Full Text Available The growing rate of sexual risk-taking among young people contributes significantly to the spread of the HIV/AIDS epidemic in Nigeria. This study, explores the influence of socio-demographic, HIV/AIDS awareness and female empowerment on the sexual risk behaviors of unmarried Nigerian women aged 15-24. The data presented in this paper was drawn from the 2003 Nigeria National Demographic and Health Survey. The sample consisted of unmarried women aged 15-24 in the dataset. Data was collected through a structured and interviewer administered questionnaire. Multivariate logistic regression models were used to identify the most important predictors of sexual risk behaviors. Sexual risk-taking is relatively high among unmarried young women. Among those who are sexually active, 80% indicated that they did not use a condom during their first sexual encounter. Regression analysis revealed that younger age, lower HIV/AIDS prevention and transmission knowledge, lower knowledge of where to obtain condoms, lower material standard of living and greater intimate partner violence were significantly associated with sexual risk-taking in this population. Findings revealed that the sexual behavior of unmarried Nigerian women aged 15-24 is influenced by a complex matrix of factors. Identifying specific processes and contexts that promote the concentration of risk among sub-sections of young unmarried women aged 15-24 years in Nigeria should be a research and intervention priority.

  5. Comparison of the accuracy of the London atlas and Smith method in dental age estimation in 5-15.99-year-old Iranians using the panoramic view.

    Science.gov (United States)

    Ghafari, Roshanak; Ghodousi, Arash; Poordavar, Esmaeil

    2018-03-07

    Tooth development is widely used for age estimation and staging physical maturity. It is of great importance in dental age estimation in forensic dentistry, orthodontic treatment planning, and pediatric endocrinology. This study aimed to compare the accuracy of two age estimation methods, i.e., the London Atlas and Smith's method, using the panoramic view of developing teeth. In this descriptive-analytic study, panoramic radiographs of 339 healthy individuals, including 145 boys and 194 girls, were assessed. The participants aged between 5.00 and 15.99 years. Dental age of the subjects was determined by the London Atlas of Human Tooth Development and Eruption and Smith's method. The collected information was entered in the SPSS software (Ver.18). Differences and correlations between chronological and dental age were assessed by paired t tests and Pearson's correlation analysis. In all analyzes, the significance level was considered less than 0.05. The mean chronological age of the subjects was 10.13 ± 2.92 years. The mean ages estimated by the London Atlas and Smith's method were 10.29 ± 2.91 and 9.89 ± 2.84 years, respectively. Paired t test showed that the differences between the mean chronological age and mean estimated ages using the London Atlas and Smith's method were not significant (P = 0.15 and 0.16, respectively). Our findings showed that both methods had high accuracy for age estimation, but the London Atlas is easier to use.

  6. Helping Students Cope in an Age of Terrorism: Strategies for School Counselors

    Science.gov (United States)

    Chibbaro, Julia S.; Jackson, C. Marie

    2006-01-01

    School counselors experience unique challenges as they struggle to provide students with coping skills geared to the outside world including acts of terrorism. School-aged students in the United States are one of the most vulnerable populations in the event of a terrorist act. This article offers a review of the current and most relevant…

  7. Going up in Dreams and Esteem: Cross-Age Mentoring to Promote Leadership Skills in High School-Age Gifted Students

    Science.gov (United States)

    Besnoy, Kevin D.; McDaniel, Sara C.

    2016-01-01

    Mentoring programs are an effective way to offer gifted students authentic learning opportunities. Although there are many mentoring models, the fundamental relationship between mentor and mentee has remained consistent throughout the ages. One mentoring model that has recently grown in popularity is the cross-age mentoring model. In this model,…

  8. Methods for sequential resonance assignment in solid, uniformly 13C, 15N labelled peptides: Quantification and application to antamanide

    International Nuclear Information System (INIS)

    Detken, Andreas; Hardy, Edme H.; Ernst, Matthias; Kainosho, Masatsune; Kawakami, Toru; Aimoto, Saburo; Meier, Beat H.

    2001-01-01

    The application of adiabatic polarization-transfer experiments to resonance assignment in solid, uniformly 13 C- 15 N-labelled polypeptides is demonstrated for the cyclic decapeptide antamanide. A homonuclear correlation experiment employing the DREAM sequence for adiabatic dipolar transfer yields a complete assignment of the C α and aliphatic side-chain 13 C resonances to amino acid types. The same information can be obtained from a TOBSY experiment using the recently introduced P9 1 12 TOBSY sequence, which employs the J couplings as a transfer mechanism. A comparison of the two methods is presented. Except for some aromatic phenylalanine resonances, a complete sequence-specific assignment of the 13 C and 15 N resonances in antamanide is achieved by a series of selective or broadband adiabatic triple-resonance experiments. Heteronuclear transfer by adiabatic-passage Hartmann-Hahn cross polarization is combined with adiabatic homonuclear transfer by the DREAM and rotational-resonance tickling sequences into two- and three-dimensional experiments. The performance of these experiments is evaluated quantitatively

  9. Benchmark fragment-based 1H, 13C, 15N and 17O chemical shift predictions in molecular crystals†

    Science.gov (United States)

    Hartman, Joshua D.; Kudla, Ryan A.; Day, Graeme M.; Mueller, Leonard J.; Beran, Gregory J. O.

    2016-01-01

    The performance of fragment-based ab initio 1H, 13C, 15N and 17O chemical shift predictions is assessed against experimental NMR chemical shift data in four benchmark sets of molecular crystals. Employing a variety of commonly used density functionals (PBE0, B3LYP, TPSSh, OPBE, PBE, TPSS), we explore the relative performance of cluster, two-body fragment, and combined cluster/fragment models. The hybrid density functionals (PBE0, B3LYP and TPSSh) generally out-perform their generalized gradient approximation (GGA)-based counterparts. 1H, 13C, 15N, and 17O isotropic chemical shifts can be predicted with root-mean-square errors of 0.3, 1.5, 4.2, and 9.8 ppm, respectively, using a computationally inexpensive electrostatically embedded two-body PBE0 fragment model. Oxygen chemical shieldings prove particularly sensitive to local many-body effects, and using a combined cluster/fragment model instead of the simple two-body fragment model decreases the root-mean-square errors to 7.6 ppm. These fragment-based model errors compare favorably with GIPAW PBE ones of 0.4, 2.2, 5.4, and 7.2 ppm for the same 1H, 13C, 15N, and 17O test sets. Using these benchmark calculations, a set of recommended linear regression parameters for mapping between calculated chemical shieldings and observed chemical shifts are provided and their robustness assessed using statistical cross-validation. We demonstrate the utility of these approaches and the reported scaling parameters on applications to 9-tertbutyl anthracene, several histidine co-crystals, benzoic acid and the C-nitrosoarene SnCl2(CH3)2(NODMA)2. PMID:27431490

  10. Benchmark fragment-based (1)H, (13)C, (15)N and (17)O chemical shift predictions in molecular crystals.

    Science.gov (United States)

    Hartman, Joshua D; Kudla, Ryan A; Day, Graeme M; Mueller, Leonard J; Beran, Gregory J O

    2016-08-21

    The performance of fragment-based ab initio(1)H, (13)C, (15)N and (17)O chemical shift predictions is assessed against experimental NMR chemical shift data in four benchmark sets of molecular crystals. Employing a variety of commonly used density functionals (PBE0, B3LYP, TPSSh, OPBE, PBE, TPSS), we explore the relative performance of cluster, two-body fragment, and combined cluster/fragment models. The hybrid density functionals (PBE0, B3LYP and TPSSh) generally out-perform their generalized gradient approximation (GGA)-based counterparts. (1)H, (13)C, (15)N, and (17)O isotropic chemical shifts can be predicted with root-mean-square errors of 0.3, 1.5, 4.2, and 9.8 ppm, respectively, using a computationally inexpensive electrostatically embedded two-body PBE0 fragment model. Oxygen chemical shieldings prove particularly sensitive to local many-body effects, and using a combined cluster/fragment model instead of the simple two-body fragment model decreases the root-mean-square errors to 7.6 ppm. These fragment-based model errors compare favorably with GIPAW PBE ones of 0.4, 2.2, 5.4, and 7.2 ppm for the same (1)H, (13)C, (15)N, and (17)O test sets. Using these benchmark calculations, a set of recommended linear regression parameters for mapping between calculated chemical shieldings and observed chemical shifts are provided and their robustness assessed using statistical cross-validation. We demonstrate the utility of these approaches and the reported scaling parameters on applications to 9-tert-butyl anthracene, several histidine co-crystals, benzoic acid and the C-nitrosoarene SnCl2(CH3)2(NODMA)2.

  11. Affordable uniform isotope labeling with {sup 2}H, {sup 13}C and {sup 15}N in insect cells

    Energy Technology Data Exchange (ETDEWEB)

    Sitarska, Agnieszka; Skora, Lukasz; Klopp, Julia; Roest, Susan; Fernández, César; Shrestha, Binesh; Gossert, Alvar D., E-mail: alvar.gossert@novartis.com [Novartis Institutes for BioMedical Research (Switzerland)

    2015-06-15

    For a wide range of proteins of high interest, the major obstacle for NMR studies is the lack of an affordable eukaryotic expression system for isotope labeling. Here, a simple and affordable protocol is presented to produce uniform labeled proteins in the most prevalent eukaryotic expression system for structural biology, namely Spodoptera frugiperda insect cells. Incorporation levels of 80 % can be achieved for {sup 15}N and {sup 13}C with yields comparable to expression in full media. For {sup 2}H,{sup 15}N and {sup 2}H,{sup 13}C,{sup 15}N labeling, incorporation is only slightly lower with 75 and 73 %, respectively, and yields are typically twofold reduced. The media were optimized for isotope incorporation, reproducibility, simplicity and cost. High isotope incorporation levels for all labeling patterns are achieved by using labeled algal amino acid extracts and exploiting well-known biochemical pathways. The final formulation consists of just five commercially available components, at costs 12-fold lower than labeling media from vendors. The approach was applied to several cytosolic and secreted target proteins.

  12. A new organic reference material, l-glutamic acid, USGS41a, for δ(13) C and δ(15) N measurements - a replacement for USGS41.

    Science.gov (United States)

    Qi, Haiping; Coplen, Tyler B; Mroczkowski, Stanley J; Brand, Willi A; Brandes, Lauren; Geilmann, Heike; Schimmelmann, Arndt

    2016-04-15

    The widely used l-glutamic acid isotopic reference material USGS41, enriched in both (13) C and (15) N, is nearly exhausted. A new material, USGS41a, has been prepared as a replacement for USGS41. USGS41a was prepared by dissolving analytical grade l-glutamic acid enriched in (13) C and (15) N together with l-glutamic acid of normal isotopic composition. The δ(13) C and δ(15) N values of USGS41a were directly or indirectly normalized with the international reference materials NBS 19 calcium carbonate (δ(13) CVPDB = +1.95 mUr, where milliurey = 0.001 = 1 ‰), LSVEC lithium carbonate (δ(13) CVPDB = -46.6 mUr), and IAEA-N-1 ammonium sulfate (δ(15) NAir = +0.43 mUr) and USGS32 potassium nitrate (δ(15) N = +180 mUr exactly) by on-line combustion, continuous-flow isotope-ratio mass spectrometry, and off-line dual-inlet isotope-ratio mass spectrometry. USGS41a is isotopically homogeneous; the reproducibility of δ(13) C and δ(15) N is better than 0.07 mUr and 0.09 mUr, respectively, in 200-μg amounts. It has a δ(13) C value of +36.55 mUr relative to VPDB and a δ(15) N value of +47.55 mUr relative to N2 in air. USGS41 was found to be hydroscopic, probably due to the presence of pyroglutamic acid. Experimental results indicate that the chemical purity of USGS41a is substantially better than that of USGS41. The new isotopic reference material USGS41a can be used with USGS40 (having a δ(13) CVPDB value of -26.39 mUr and a δ(15) NAir value of -4.52 mUr) for (i) analyzing local laboratory isotopic reference materials, and (ii) quantifying drift with time, mass-dependent isotopic fractionation, and isotope-ratio-scale contraction for isotopic analysis of biological and organic materials. Published in 2016. This article is a U.S. Government work and is in the public domain in the USA. Published in 2016. This article is a U.S. Government work and is in the public domain in the USA.

  13. Students' Autobiographical Memory of Participation in Multiple Sport Education Seasons

    Science.gov (United States)

    Sinelnikov, Oleg A.; Hastie, Peter A.

    2010-01-01

    This study examines the recollections of the Sport Education experiences of a cohort of students (15 boys and 19 girls) who had participated in seasons of basketball, soccer and badminton across grades six through eight (average age at data collection = 15.6 years). Using autobiographic memory theory techniques, the students completed surveys and…

  14. Victims of Cyberbullying in the Region of Murcia: A Quantitative Study with High School Students

    Directory of Open Access Journals (Sweden)

    Victor González Calatayud

    2018-01-01

    Full Text Available The fact that technologies have become a normal part of our lives has meant that bullying and other problems have shifted towards the virtual, hence complicating possible solutions. While before peer harassment occurred mainly at school, today Information and Communications Technology (ICT means that children now have no place to “hide” from this problem. This and other features, like anonymity, have led many people to believe that this problem is more serious than traditional bullying. The purpose of this research was to determine the incidence of this phenomenon and its impact on students in compulsory secondary education in the Region of Murcia, specifically the prevalence of victimization and differences in relation to gender, age and academic year. One of the main results is that 49.3% of students have suffered from one or more cyberbullying behaviours. Greater victimization of females was observed in fourth of ESO and at higher ages (age ranges: 11-13; 14-15; 16-18. These results show the reality of secondary schools and the need to establish effective measures to solve this problem.

  15. Patterns of δ13C and δ15N in wolverine Gulo gulo tissues from the Brooks Range, Alaska

    Directory of Open Access Journals (Sweden)

    Fredrik DALERUM

    2009-06-01

    Full Text Available Knowledge of carnivore diets is essential to understand how carnivore populations respond demographically to variations in prey abundance. Analysis of stable isotopes is a useful complement to traditional methods of analyzing carnivore diets. We used data on d13C and d15N in wolverine tissues to investigate patterns of seasonal and annual diet variation in a wolverine Gulo gulo population in the western Brooks Range, Alaska, USA. The stable isotope ratios in wolverine tissues generally reflected that of terrestrial carnivores, corroborating previous diet studies on wolverines. We also found variation in d13C and d15N both between muscle samples collected over several years and between tissues with different assimilation rates, even after correcting for isotopic fractionation. This suggests both annual and seasonal diet variation. Our results indicate that data on d13C and d15N holds promise for qualitative assessments of wolverine diet changes over time. Such temporal variation may be important indicators of ecological responses to environmental perturbations, and we suggest that more refined studies of stable isotopes may be an important tool when studying temporal change in diets of wolverines and similar carnivores [Current Zoology 55(3: 188–192, 2009].

  16. Beverage Consumption Patterns at Age 13 to 17 Years Are Associated with Weight, Height, and Body Mass Index at Age 17 Years.

    Science.gov (United States)

    Marshall, Teresa A; Van Buren, John M; Warren, John J; Cavanaugh, Joseph E; Levy, Steven M

    2017-05-01

    Sugar-sweetened beverages (SSBs) have been associated with obesity in children and adults; however, associations between beverage patterns and obesity are not understood. Our aim was to describe beverage patterns during adolescence and associations between adolescent beverage patterns and anthropometric measures at age 17 years. We conducted a cross-sectional analyses of longitudinally collected data. Data from participants in the longitudinal Iowa Fluoride Study having at least one beverage questionnaire completed between ages 13.0 and 14.0 years, having a second questionnaire completed between 16.0 and 17.0 years, and attending clinic examination for weight and height measurements at age 17 years (n=369) were included. Beverages were collapsed into four categories (ie, 100% juice, milk, water and other sugar-free beverages, and SSBs) for the purpose of clustering. Five beverage clusters were identified from standardized age 13 to 17 years mean daily beverage intakes and named by the authors for the dominant beverage: juice, milk, water/sugar-free beverages, neutral, and SSB. Weight, height, and body mass index (BMI; calculated as kg/m 2 ) at age 17 years were analyzed. We used Ward's method for clustering of beverage variables, one-way analysis of variance and χ 2 tests for bivariable associations, and γ-regression for associations of weight or BMI (outcomes) with beverage clusters and demographic variables. Linear regression was used for associations of height (outcome) with beverage clusters and demographic variables. Participants with family incomes beverage cluster membership. For example, on average, male and female members of the neutral cluster were 4.5 cm (P=0.010) and 4.2 cm (P=0.034) shorter, respectively, than members of the milk cluster. For members of the juice cluster, mean BMI was lower than for members of the milk cluster (by 2.4 units), water/sugar-free beverage cluster (3.5 units), neutral cluster (2.2 units), and SSB cluster (3.2 units) (all

  17. The maternal age-related first trimester risks for trisomy 21, 18 and 13 based on Danish first trimester data from 2005 to 2014

    DEFF Research Database (Denmark)

    Hartwig, Tanja Schlaikjær; Sørensen, Steen; Jørgensen, Finn Stener

    2016-01-01

    OBJECTIVES: Most currently used age-related risks of T21, T18 and T13 are based on estimates of the live-birth prevalence, and describe an exponential increase of risk by increased maternal age. We investigated the first trimester prevalence of T21, T18 and T13 in a large population of Danish women......) / slope)) was found to best describe the age-related risk of T21, T18 and T13. CONCLUSION: We found that the age-related risks are better described by sigmoidal functions, contrary to the widely assumed exponential functions. Our results indicate a lower age-related a priori risk of T21, T18 and T13...

  18. Prototropic tautomerism of 5-nitrobenzimidazole derivatives in {sup 1}H, {sup 13}C and {sup 15}N NMR spectra; Tautomeria prototropowa pochodnych 5-nitrobenzimidazolu w widmach {sup 1}H, {sup 13}C, {sup 15}N NMR

    Energy Technology Data Exchange (ETDEWEB)

    Wiench, J W; Bocian, W; Stefaniak, L [Inst. Chemii Organicznej, Polska Akademia Nauk, Warsaw (Poland)

    1994-12-31

    NMR spectra of 5-nitrobenzimidazole derivatives in DMSO solution show the fast exchange of protons. The line broadening in {sup 1}H,{sup 13}C and {sup 15}N spectra have been observed. The interpretation of the spectra has been done basing on chemical shifts values and couplings between nuclei in the investigated derivatives. 3 refs, 2 figs, 3 tabs.

  19. Gingival recession in school kids aged 10-15 years in Udaipur, India

    Directory of Open Access Journals (Sweden)

    Mathur Anmol

    2009-01-01

    Full Text Available Aim : The study aimed to determine the incidence of gingival recession in the mandibular central incisor region among school children aged 10-15 years in Udaipur (India. Materials and Methods : A sample of 1800 males and female kids were examined in a mobile dental unit. World Health Organisation (WHO rules and standards were followed. Result : Gingival recession, when compared, with respect to age, mean clinical crown length, anterior crowding and frenal involvement was significant (p less than 0.00 with respect to affected teeth.

  20. Sleep behaviors in traditional-age college students: A state of the science review with implications for practice.

    Science.gov (United States)

    Owens, Heather; Christian, Becky; Polivka, Barbara

    2017-11-01

    The purpose of this systematic review was to examine influences affecting sleep behavior in traditional-age college students and to advocate for improved sleep behavior assessments. A literature search of CINAHL, MEDLINE, and PubMed databases was performed using the search terms "college students" and "sleep" in the title that were published in English from 1978 to 2016. The circadian clock is reset in traditional-age college students leading to delayed sleep times. Newly realized autonomy and increased use of technology also prevent traditional-age college students from obtaining sufficient sleep. Insufficient sleep experienced by these students has been linked to insulin resistance, hypertension, diabetes, weight gain, and stress. Sleep insufficiency increases the risk for pedestrian, motor vehicle, and domestic and occupational injuries. Insufficient sleep may result in poor academic performance influencing subsequent health outcomes. Evidence supports the need for nurse practitioners and other healthcare providers to incorporate systematic sleep behavior assessments to improve health outcomes among traditional-age college students. ©2017 American Association of Nurse Practitioners.

  1. Association between Sleep Duration and Overweight/Obesity at Age 7–18 in Shenyang, China in 2010 and 2014

    Directory of Open Access Journals (Sweden)

    Qi Sun

    2018-04-01

    Full Text Available This study was designed to examine the association between sleep duration and being overweight/obese in primary, middle, and high school students. This was a multiple cross-sectional study using data from the 2010 and 2014 National Survey on Students’ Constitution and Health (CNSSCH. A total of 23,602 students aged 7–18 years were enrolled in this study. The prevalence of being overweight and obese—stratified by age, gender, and sleep duration—in 2010 and 2014 were compared. Sleep duration was categorized as <7 h, ≥7 to 8 h, ≥8 to 9 h, and ≥9 h. Overweight and obesity were defined according to the cut-point criteria in China. Multivariable logistic regression results in 2010 and 2014 revealed that students sleeping <7 h and aged 7–12 years had an increased risk of becoming overweight/obese. In 2010, the adjusted prevalence ratios of overweight for 7–12-year-old students sleeping <9 h was 1.196 (95%CI: 1.004–1.424 and 1315-year-old students sleeping <8 h was 1.265 (95%CI: 1.023–1.565. In 2014, the adjusted prevalence ratios of overweight and obesity for 7–12-year-old students sleeping <9 h were 1.295 (95%CI: 1.091–1.537 and 1.231 (95%CI: 1.045–1.449; 16–18-year-old students sleeping <7 h were 1.530 (95%CI: 1.239–1.888 and 1.585 (95%CI: 1.270–2.081. Our study revealed that different levels of sleep curtailment increased the risk of becoming overweight/obesity in different age groups of students.

  2. Stress and Coping Strategies of Students in a Medical Faculty in Malaysia

    Science.gov (United States)

    Al-Dubai, Sami Abdo Radman; Al-Naggar, Redhwan Ahmed; Alshagga, Mustafa Ahmed; Rampal, Krishna Gopal

    2011-01-01

    Background: Stress may affect students’ health and their academic performance. Coping strategies are specific efforts that individuals employ to manage stress. This study aimed to assess the perception of stress among medical students and their coping strategies. Methods: A cross-sectional study was conducted among 376 medical and medical sciences undergraduates in Management and Science University in Malaysia. Stress was assessed by a global rating of stress. Sources of stress were assessed using a 17-item questionnaire. The validated Brief COPE inventory was used to assess coping strategies. Results: The majority of respondents were females (64.4%), aged 21 years or older (63.0%), and were Malays (68.9%). Forty-six percent felt stress. The most common stressor was worries of the future (71.0%), followed by financial difficulties (68.6%). Significant predictors of stress were smoking (OR = 2.9, 95% CI 1.3–6.8, P = 0.009), worries of the future (OR = 2.1, 95% CI 1.3–3.4, P = 0.005), self-blame (OR = 1.3, 95% CI 1.1–1.5, P = 0.001), lack of emotional support (OR = 0.8, 95% CI 0.7–0.9, P = 0.017), and lack of acceptance (OR = 0.8, 95% CI 0.6–0.9, P = 0.010). Students used active coping, religious coping reframing, planning, and acceptance to cope with stress. Conclusion: Stressors reported by the students were mainly financial and academic issues. Students adopted active coping strategies rather than avoidance. Students should receive consultation on how to manage and cope with stress. PMID:22135602

  3. Transmission electron microscopy of Ti-12Mo-13Nb Alloy aged after heat forging

    International Nuclear Information System (INIS)

    Oliveira, Nathalia Rodrigues; Baldan, Renato; Gabriel, Sinara Borborema

    2014-01-01

    Metastable β-Ti alloys possess mechanical properties, in particular a elastic modulus that depends not only on its composition but also the applied thermomechanical treatments. These alloys require high mechanical strength and a low Young’s modulus to avoid stress shielding. Preliminary studies on the development of Ti- 13Nb-12Mo alloy showed than the better properties were obtained at aged at 500 ° C / 24 h after cold forging , whose microstructure consisted of bimodal α phase in the β matrix. In this work, Ti-12Mo-13Nb alloy was heat forged and aged at 500 deg C for 24h and the microstructure was analyzed by employing X-ray diffraction and transmission electron microscopy. According to the results, while the cold forging resulted in bimodal α phase in the β matrix, hot forging resulted in a fine and homogeneous α phase in the β matrix. (author)

  4. Violence behavior and factors associated among students of Central-West Brazil.

    Science.gov (United States)

    Castro, Marta de Lima; Cunha, Sergio Souza da; Souza, Delma P Oliveira de

    2011-12-01

    To estimate the prevalence of violence among adolescents and young adults and to identify associated factors. Cross-sectional study carried out in 2008 with systematic random sampling of 699 elementary and high school students enrolled in urban state schools of Barra do Garças, Central-Western Brazil. A self-administered questionnaire was applied in the classrooms without the presence of the teacher. The outcome "violent behavior" was defined as (1) use of firearm or sharp instrument, and/or (2) aggression against oneself and/or others, and/or (3) suicide attempt. The analyzed independent variables were age, gender, socioeconomic status, use of alcohol, use of psychoactive drugs, sexual activity, and relationship between parents. Univariate analysis was conducted, as well as multiple regression adjusted for effect of clustering. Violence prevalence was of 18.6%, varying with age: 10.1% in the group aged 10 and 11 years; 20.2% for those aged 12-19 years; and 4.5% in the group aged 20-21 years. The factors associated with violent behavior were use of alcohol (RP = 2.51, 95%CI 1.22;5.15), use of psychoactive drugs (RP = 2.10, 95%CI 1.61;2.75), male gender (RP = 1.63, 95%CI 1.13;2.35) and unsatisfactory relationship between parents (RP = 1.64, 95%CI 1.25;2.15). Results indicate high prevalence of violence among adolescents in the age group 12-19 years, mainly among users of alcohol and drugs, of the male sex, from families whose parents do not have satisfactory relationships. Although without statistical significance in the final regression model, school result discrepancy and socioeconomic level should be considered in educational actions for prevention of violence behavior among students.

  5. {sup 13}C, {sup 15}N Resonance Assignment of Parts of the HET-s Prion Protein in its Amyloid Form

    Energy Technology Data Exchange (ETDEWEB)

    Siemer, Ansgar B. [Physical Chemistry (Switzerland); Ritter, Christiane [Salk Institute, Structural Biology Laboratory (United States); Steinmetz, Michel O. [Paul Scherrer Institut, Biomolecular Research, Structural Biology (Switzerland); Ernst, Matthias [Physical Chemistry (Switzerland); Riek, Roland [Salk Institute, Structural Biology Laboratory (United States); Meier, Beat H. [Physical Chemistry (Switzerland)

    2006-02-15

    The partial {sup 15}N and {sup 13}C solid-state NMR resonance assignment of the HET-s prion protein fragment 218-289 in its amyloid form is presented. It is based on experiments measured at MAS frequencies in the range of 20-40 kHz using exclusively adiabatic polarization-transfer schemes. The resonance assignment within each residue is based on two-dimensional {sup 13}C--{sup 13}C correlation spectra utilizing the DREAM mixing scheme. The sequential linking of the assigned residues used a set of two- and three-dimensional {sup 15}N--{sup 13}C correlation experiments. Almost all cross peaks visible in the spectra are assigned, but only resonances from 43 of the 78 amino-acid residues could be detected. The missing residues are thought to be highly disordered and/or highly dynamic giving rise to broad resonance lines that escaped detection in the experiments applied. The line widths of the observed resonances are narrow and comparable to line widths observed in micro-crystalline samples. The 43 assigned residues are located in two fragments of about 20 residues.

  6. Interferometric imaging of Titan's HC$_3$N, H$^{13}$CCCN and HCCC$^{15}$N

    OpenAIRE

    Cordiner, M. A.; Nixon, C. A.; Charnley, S. B.; Teanby, N. A.; Molter, E. M.; Kisiel, Z.; Vuitton, V.

    2018-01-01

    We present the first maps of cyanoacetylene isotopologues in Titan's atmosphere, including H$^{13}$CCCN and HCCC$^{15}$N, detected in the 0.9 mm band using the Atacama Large Millimeter/submillimeter array (ALMA) around the time of Titan's (southern winter) solstice in May 2017. The first high-resolution map of HC$_3$N in its $v_7=1$ vibrationally excited state is also presented, revealing a unique snapshot of the global HC$_3$N distribution, free from the strong optical depth effects that adv...

  7. Spisevaner og sundhedsadfaerd blandt 11-15 årige

    DEFF Research Database (Denmark)

    Due, P; Holstein, B E; Ito, H

    1991-01-01

    A total of 1,671 school children aged 11, 13 and 15 years answered a questionnaire on diet, other health behaviour, social background, social network, health and life satisfaction. The proportions who ate fruit, vegetables, and rye bread every day were 77%, 64% and 94%. Moreover, 78% had fibre...... the healthy diet components but an increasing consumption of unhealthy components with increasing age. Among girls we found a decreasing consumption of both healthy and unhealthy components with increasing age. Healthy diet was associated with high social class, good health, positive life satisfaction...

  8. Trace metals analysis of hair samples from students in metropolitan area high school

    International Nuclear Information System (INIS)

    Chiu, S.F.; Wang, P.C.; Kao, P.F.; Chung Shan Medical University, Taichung, Taiwan; Lin, J.B.; Chung Shan Medical University, Taichung, Taiwan; Lin, D.B.; Chen, C.Y.

    2011-01-01

    Hair samples from junior high school students in metropolitan areas of Taichung, Taiwan were tested for a total of 13 elements, Al, Ag, Br, Cl, Cr, Fe, K, La, Mn, Na, Sc, Se, and Zn by instrumental neutron activation analysis (INAA) to establish seasonal variations, gender and environmental exposures. The seasonal variations of hairs in 39 healthy students (18 males and 21 females; age 13.3 ± 0.4 years; height, 158.0 ± 4.1 cm; weight, 53.4 ± 5.7 kg) were collected at 1.5-month intervals for 1 year starting from late August, 2008. The concentrations of the above elements varied from 10 3 to 10 -2 μg g -1 at different sampling times. A quantified index of agreement (AT) was introduced to help classify the elements. A smaller AT indicated highly consistent quantities of specific metals in the hair while a larger AT indicated increased fluctuation, i.e., less agreement. The different ATs in various hair samples were discussed. The concentrations of these elements are compared with the data in the literature. (author)

  9. Trisomy 15 with loss of the paternal 15 as a cause of Prader-Willi syndrome due to maternal disomy

    Energy Technology Data Exchange (ETDEWEB)

    Cassidy, S.B.; Lai, Li-Wen; Erickson, R.P. (Univ. of Arizona College of Medicine, Tucson, AZ (United States)); Magnuson, L.; Thomas, E.; Herrmann, J. (Great Lakes Genetics, Milwaukee, AZ (United States)); Gendron, R. (Great Lakes Genetics, Kingsport, TN (United States))

    1992-10-01

    Uniparental disomy has recently been recognized to cause human disorders, including Prader-Willi syndrome (PWS). The authors describe a particularly instructive case which raises important issues concerning the mechanisms producing uniparental disomy and whose evaluation provides evidence that trisomy may precede uniparental disomy in a fetus. Chorionic villus sampling performed for advanced maternal age revealed trisomy 15 in all direct and cultured cells, though the fetus appeared normal. Chromosome analysis of amniocytes obtained at 15 wk was normal in over 100 cells studied. The child was hypotonic at birth, and high-resolution banding failed to reveal the deletion of 15q11-13, a deletion which is found in 50%-70% of patients with PWS. Over time, typical features of PWS developed. Molecular genetic analysis using probes for chromosome 15 revealed maternal disomy. Maternal nondisjunction with fertilization of a disomic egg by a normal sperm, followed by loss of the paternal 15, is a likely cause of confined placental mosaicism and uniparental disomy in this case of PWS, and advanced maternal age may be a predisposing factor. 38 refs., 3 figs., 2 tabs.

  10. 45 CFR 91.13 - Exceptions to the rules against age discrimination: Normal operation or statutory objective of...

    Science.gov (United States)

    2010-10-01

    ... objective of any program or activity. A recipient is permitted to take an action, otherwise prohibited by...: Normal operation or statutory objective of any program or activity. 91.13 Section 91.13 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION NONDISCRIMINATION ON THE BASIS OF AGE IN...

  11. The prevalence of type 1 diabetes mellitus among 15-34-year-aged Lithuanian inhabitants during 1991-2010.

    Science.gov (United States)

    Ostrauskas, Rytas

    2015-04-01

    To summarize the data on the prevalence of type 1 diabetes mellitus among 15-34-year-aged Lithuania inhabitants (1991-2010). New prevalent cases consist of growing-up patients with diabetes onset in childhood, i.e., up to 14 years, new onset 15-34-year-aged type 1 diabetic patients Lithuanian inhabitants, and immigrants. The data on type 1 diabetes was collected with the help of general practitioners and regional endocrinologists in Lithuania. On 31 December 1991, there were 1202 adolescent and adult 15-34-year-aged patients with type 1 diabetes mellitus or 103.59 per 100,000 inhabitants of the same age group (95% Poisson CI 97.90-109.62), and at the end of 2010 - 1533 or 187.80 (178.63-197.44), respectively in Lithuania. During 19-year period the mean increase of type 1 diabetic patients was 1.25±1.94% per year or 1.47±2.74 per 100,000 inhabitants per mean year of the study period (for males 1.42±2.14% or 1.69±3.05/100,000 and for females 1.05±1.99%, or 1.24±2.92/100,000). Regression-based linear trends showed that the prevalence of type 1 diabetes mellitus in 15-34-year-age group had a tendency to increase among males (r=0.953; p1) and females (r=0.970; p1). The age adjusted prevalence frequencies for males and females in 1991 were correspondingly 102.81/100,000 and 104.55/100,000, and in 2010 - 193.75 and 182.01. The prevalence of type 1 diabetes mellitus among 15-34-year-age males and females had a tendency to increase during 1991-2010. Copyright © 2014 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.

  12. Substance Use among Medical Students in Kathmandu Valley

    Directory of Open Access Journals (Sweden)

    P Khanal

    2010-12-01

    Full Text Available Introduction: Substance use including tobacco and alcohol is the most important cause of preventable morbidity, disability, and premature mortality. The study aims to specify the prevalence and the pattern of use of different substance. Methods: A cross sectional study was performed amongst first year and final year students in four medical colleges in Kathmandu using self administered anonymous questionnaire.Data collectedfrom 446 students were analyzed. Results: Prevalence of substance use was found to be 60.3% among the medical students. Alcohol (57.6% was the substance most prevalently used followed by tobacco (27.58% and cannabis (12.8%. Mean age of first exposure was 17.94 (Confidence interval: 17.91-17.97. There was significant difference in the useof tobacco and cannabis amongst final year students than first year students. Male and female differed significantly in use of every substance except for benzodiazepine. Medical college, college and school were place of first exposure in 17.26%, 15.92% and 13.23% of the cases respectively. Family history was associated with substance use in medical students and was statistically significant (P<0.0001.Experimentation was the major reason for the use of most of the substances. Conclusions: Substance use is prevalent in male medical students of both first and final year. Hence steps should be initiated early in school, college and medical college to prevent substance use. Keywords: alcohol, medical students, substance use, tobacco.

  13. Birth order modifies the effect of IL13 gene polymorphisms on serum IgE at age 10 and skin prick test at ages 4, 10 and 18: a prospective birth cohort study

    Science.gov (United States)

    2010-01-01

    Background Susceptibility to atopy originates from effects of the environment on genes. Birth order has been identified as a risk factor for atopy and evidence for some candidate genes has been accumulated; however no study has yet assessed a birth order-gene interaction. Objective To investigate the interaction of IL13 polymorphisms with birth order on allergic sensitization at ages 4, 10 and 18 years. Methods Mother-infant dyads were recruited antenatally and followed prospectively to age 18 years. Questionnaire data (at birth, age 4, 10, 18); skin prick test (SPT) at ages 4, 10, 18; total serum IgE and specific inhalant screen at age 10; and genotyping for IL13 were collected. Three SNPs were selected from IL13: rs20541 (exon 4, nonsynonymous SNP), rs1800925 (promoter region) and rs2066960 (intron 1). Analysis included multivariable log-linear regression analyses using repeated measurements to estimate prevalence ratios (PRs). Results Of the 1456 participants, birth order information was available for 83.2% (1212/1456); SPT was performed on 67.4% at age 4, 71.2% at age 10 and 58.0% at age 18. The prevalence of atopy (sensitization to one or more food or aeroallergens) increased from 19.7% at age 4, to 26.7% at 10 and 41.1% at age 18. Repeated measurement analysis indicated interaction between rs20541 and birth order on SPT. The stratified analyses demonstrated that the effect of IL13 on SPT was restricted only to first-born children (p = 0.007; adjusted PR = 1.35; 95%CI = 1.09, 1.69). Similar findings were noted for firstborns regarding elevated total serum IgE at age 10 (p = 0.007; PR = 1.73; 1.16, 2.57) and specific inhalant screen (p = 0.034; PR = 1.48; 1.03, 2.13). Conclusions This is the first study to show an interaction between birth order and IL13 polymorphisms on allergic sensitization. Future functional genetic research need to determine whether or not birth order is related to altered expression and methylation of the IL13 gene. PMID:20403202

  14. Birth order modifies the effect of IL13 gene polymorphisms on serum IgE at age 10 and skin prick test at ages 4, 10 and 18: a prospective birth cohort study

    Directory of Open Access Journals (Sweden)

    Ogbuanu Ikechukwu U

    2010-04-01

    Full Text Available Abstract Background Susceptibility to atopy originates from effects of the environment on genes. Birth order has been identified as a risk factor for atopy and evidence for some candidate genes has been accumulated; however no study has yet assessed a birth order-gene interaction. Objective To investigate the interaction of IL13 polymorphisms with birth order on allergic sensitization at ages 4, 10 and 18 years. Methods Mother-infant dyads were recruited antenatally and followed prospectively to age 18 years. Questionnaire data (at birth, age 4, 10, 18; skin prick test (SPT at ages 4, 10, 18; total serum IgE and specific inhalant screen at age 10; and genotyping for IL13 were collected. Three SNPs were selected from IL13: rs20541 (exon 4, nonsynonymous SNP, rs1800925 (promoter region and rs2066960 (intron 1. Analysis included multivariable log-linear regression analyses using repeated measurements to estimate prevalence ratios (PRs. Results Of the 1456 participants, birth order information was available for 83.2% (1212/1456; SPT was performed on 67.4% at age 4, 71.2% at age 10 and 58.0% at age 18. The prevalence of atopy (sensitization to one or more food or aeroallergens increased from 19.7% at age 4, to 26.7% at 10 and 41.1% at age 18. Repeated measurement analysis indicated interaction between rs20541 and birth order on SPT. The stratified analyses demonstrated that the effect of IL13 on SPT was restricted only to first-born children (p = 0.007; adjusted PR = 1.35; 95%CI = 1.09, 1.69. Similar findings were noted for firstborns regarding elevated total serum IgE at age 10 (p = 0.007; PR = 1.73; 1.16, 2.57 and specific inhalant screen (p = 0.034; PR = 1.48; 1.03, 2.13. Conclusions This is the first study to show an interaction between birth order and IL13 polymorphisms on allergic sensitization. Future functional genetic research need to determine whether or not birth order is related to altered expression and methylation of the IL13 gene.

  15. Correlation between the synthetic origin of methamphetamine samples and their {sup 15}N and {sup 13}C stable isotope ratios

    Energy Technology Data Exchange (ETDEWEB)

    Billault, Isabelle [Laboratoire d' Analyse Isotopique et Electrochimique de Metabolismes, CNRS UMR6006, University of Nantes, BP 92208, 44322 Nantes (France)]. E-mail: Isabelle.Billault@univ-nantes.fr; Courant, Frederique [Laboratoire d' Analyse Isotopique et Electrochimique de Metabolismes, CNRS UMR6006, University of Nantes, BP 92208, 44322 Nantes (France); Pasquereau, Leo [Laboratoire d' Analyse Isotopique et Electrochimique de Metabolismes, CNRS UMR6006, University of Nantes, BP 92208, 44322 Nantes (France); Derrien, Solene [Laboratoire d' Analyse Isotopique et Electrochimique de Metabolismes, CNRS UMR6006, University of Nantes, BP 92208, 44322 Nantes (France); Robins, Richard J. [Laboratoire d' Analyse Isotopique et Electrochimique de Metabolismes, CNRS UMR6006, University of Nantes, BP 92208, 44322 Nantes (France); Naulet, Norbert [Laboratoire d' Analyse Isotopique et Electrochimique de Metabolismes, CNRS UMR6006, University of Nantes, BP 92208, 44322 Nantes (France)

    2007-06-12

    The active ingredient of ecstasy, N-methyl-3,4-methyldioxyphenylisopropylamine (MDMA) can be manufactured by a number of easy routes from simple precursors. We have synthesised 45 samples of MDMA following the five most common routes using N-precursors from 12 different origins and three different precursors for the aromatic moiety. The {sup 13}C and {sup 15}N contents of both the precursors and the MDMA samples derived therefrom were measured by isotope ratio mass spectrometry coupled to an elemental analyser (EA-IRMS). We show that within-pathway correlation between the {sup 15}N content of the precursor and that of the derived MDMA can be strong but that no general pattern of correlation can be defined. Rather, it is evident that the {delta} {sup 15}N values of MDMA are strongly influenced by a combination of the {delta} {sup 15}N values of the source of nitrogen used, the route by which the MDMA is synthesised, and the experimental conditions employed. Multivariate analysis (PCA) based on the {delta} {sup 15}N values of the synthetic MDMA and of the {delta} {sup 15}N and {delta} {sup 13}C values of the N-precursors leads to good discrimination between the majority of the reaction conditions tested.

  16. Soft tissue thickness values for black and coloured South African children aged 6-13 years.

    Science.gov (United States)

    Briers, N; Briers, T M; Becker, P J; Steyn, M

    2015-07-01

    In children, craniofacial changes due to facial growth complicate facial approximations and require specific knowledge of soft tissue thicknesses (STT). The lack of South African juvenile STT standards of particular age groups, sex and ancestry is problematic. According to forensic artists in the South African Police Service the use of African-American values to reconstruct faces of Black South African children yields poor results. In order to perform a facial approximation that presents a true reflection of the child in question, information regarding differences in facial soft tissue at different ages, sexes and ancestry groups is needed. The aims of this study were to provide data on STT of South African Black and Coloured children and to assess differences in STT with respect to age, sex and ancestry. STT was measured using cephalograms of South African children (n=388), aged 6-13 years. After digitizing the images, STT measurements were taken at ten mid-facial landmarks from each image using the iTEM measuring program. STT comparisons between groups per age, sex and ancestry were statistically analyzed. The results showed that STT differences at lower face landmarks are more pronounced in age groups per ancestry as opposed to differences per age and sex. Generally, an increase in STT was seen between 6-10 year old groups and 11-13 year old groups, regardless of ancestry and sex, at the midphiltrum, labiale inferius, pogonion, and beneath chin landmarks. This research created a reference dataset for STT of South African children of Black and Coloured ancestry per age and sex that will be useful for facial reconstruction/approximation of juvenile remains. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  17. [Interprofessional multistation practical training in the auditorium : Implementation of the national competence-based catalog of learning objectives for undergraduate medical education in the cross-sectorial area medicine of aging and the aged at the TU Dresden].

    Science.gov (United States)

    Sauer, Maik; Görnig, Matthias; Voigt, Karen; Schübel, Jeaninne; Bergmann, Antje

    2017-12-05

    The German national competence-based catalogue of learning objectives for undergraduate medical education (NKLM) newly introduced in 2015, provides a variety of learning objectives, competences, as well as practical skills for the cross-sectorial area 7 "Medication of Aging and the Aged" (QB7). Against this background an interdisciplinary teaching concept to mediate all required teaching contents should be developed. Can an interdisciplinary multistation practical course in the auditorium, in which different tasks and skills are trained at each station meet the requirements of the NKLM? Evaluation by questionnaire and rating of answers on a 6-stage Likert scale. Analysis of the qualitative and quantitative evaluation results of 235 participating students and 13 lecturers in 2016. The interdisciplinary multistation practical course in the auditorium is fully compliant with the NKLM. All theoretical and practical contents and competences could be depicted. The subjective learning effect was assessed by students as good (mean = 2.66; SD = 0.94; N = 230). The available teaching time was rated as being too short in qualitative statements. The lecturers attested a high degree of interest by the students (mean = 2.15; SD = 0.86; N = 13), but criticized that the noise level was too loud. Compact, hands-on and interdisciplinary teaching concepts in the QB7 help to make the best use of human and spatial resources and convey all theoretical and practical teaching contents and competences from the NKLM; however, the planning, organization and implementation are very time-consuming.

  18. Hazardous Health Behaviour among Medical Students: a Study from Turkey.

    Science.gov (United States)

    Nacar, Melis; Cetinkaya, Fevziye; Baykan, Zeynep; Yilmazel, Gulay; Elmali, Ferhan

    2015-01-01

    Hazardous health behaviour in young people is an important factor that affects the individual risk for non-communicable diseases and other disorders later in life. This study aimed to determine the hazardous health behaviour of first and last class medical students of Erciyes University. This descriptive study was carried out with 240 medical students from the first and 130 students from the last (sixth) class. Data were obtained by questionnaire between March-April 2012. In total, 339 students were included with a response rate of 91.6%. Socio-demographic characteristics, school success, self-reported economic difficulties, health perceptions, hazardous health behaviour related to chronic disease, tobacco, alcohol, substance use, body weight, height, traffic, violence and nutrition were assessed in line with the literature. Of the participants; 64.0% were from first and 36.0% were from the last class. Mean ages for the first and last classes were 19.4 ± 1.5 and 24.0 ± 1.5 years, respectively. In the current study, males exhibited more hazardous behaviour than females. Sime 19.8% of the students in the study group used alcohol, 35.4% used a waterpipe, and 24.8% used tobacco at least once. These rates increased in both genders in the last class and the increase in males was significant. Some 3.8% of the students in the current study used pleasure-inducing illegal substances at least once. All the students participating in the current study were single, the number of males reported not using condoms (8.6%) was 4.56 times higher compared to females. Some 64.0% of the students did not perform physical activity lasting at least 30 minutes for five times a week, 13.0% did not sleep for mean 7-8 hours daily, males having a 2.9 times higher risk. More than 1/3 of the students did not consume cooked vegetable dishes and 1/4 did not consume fresh fruits and salads, the rates were higher among males. In the current study, hazardous health behaviour was prevalent among

  19. What Makes a Student Non-Traditional? A Comparison of Students over and under Age 25 in Online, Accelerated Psychology Courses

    Science.gov (United States)

    Tilley, Brian P.

    2014-01-01

    The growing proportion of non-traditional students, very commonly defined as students over the age of 25 (though other features vary from study to study) necessitates more studies with this increasingly relevant group participating. Recently, the growth of non-traditional universities such as those offering predominantly online, accelerated…

  20. A Longitudinal Analysis of Students' Autobiographical Memories of Participation in Multiple Sport Education Seasons

    Science.gov (United States)

    Wahl-Alexander, Zachary; Sinelnikov, Oleg; Curtner-Smith, Matthew

    2017-01-01

    The purpose of this study was to examine middle school students' recollections of their participation in a significant number of Sport Education seasons over a period of five years. Thirty-one (18 boys and 13 girls) eighth-grade students (average age at data collection = 13 years) who had all participated in at least 17 Sport Education seasons…

  1. Recommendations from the ESO-Karolinska Stroke Update Conference, Stockholm 1315 November 2016

    DEFF Research Database (Denmark)

    2017-01-01

    -Karolinska Stroke Update Meeting was held in Stockholm on 1315 November 2016. There were 10 scientific sessions discussed in the meeting and each session produced a consensus statement (Full version with background, issues, conclusions and references are published as web-material and at http...... and statistical reviews (at least one randomised controlled trial plus one statistical review). Grade B Evidence: Support from randomised controlled trials and statistical reviews (one randomised controlled trial or one statistical review). Grade C Evidence: No reasonable support from randomised controlled trials...

  2. Kinematics and age of 15 stars-photometric solar analogs

    Science.gov (United States)

    Galeev, A. I.; Shimansky, V. V.

    2008-03-01

    The radial and space velocities are inferred for 15 stars that are photometric analogs of the Sun. The space velocity components (U, V, W) of most of these stars lie within the 10-60 km/s interval. The star HD 225239, which in our previous papers we classified as a subgiant, has a space velocity exceeding 100 km/s, and belongs to the thick disk. The inferred fundamental parameters of the atmospheres of solar analogs are combined with published evolutionary tracks to estimate the masses and ages of the stars studied. The kinematics of photometric analogs is compared to the data for a large group of solar-type stars.

  3. Aerobic Capacity and Anaerobic Power Levels of the University Students

    Science.gov (United States)

    Taskin, Cengiz

    2016-01-01

    The aim of study was to analyze aerobic capacity and anaerobic power levels of the university students. Total forty university students who is department physical education and department business (age means; 21.15±1.46 years for male and age means; 20.55±1.79 years for female in department physical education), volunteered to participate in this…

  4. A new organic reference material, L-glutamic acid, USGS41a, for δ13C and δ15N measurements − a replacement for USGS41

    Science.gov (United States)

    Qi, Haiping; Coplen, Tyler B.; Mroczkowski, Stanley J.; Brand, Willi A.; Brandes, Lauren; Geilmann, Heike; Schimmelmann, Arndt

    2016-01-01

    RationaleThe widely used l-glutamic acid isotopic reference material USGS41, enriched in both 13C and 15N, is nearly exhausted. A new material, USGS41a, has been prepared as a replacement for USGS41.MethodsUSGS41a was prepared by dissolving analytical grade l-glutamic acid enriched in 13C and 15N together with l-glutamic acid of normal isotopic composition. The δ13C and δ15N values of USGS41a were directly or indirectly normalized with the international reference materials NBS 19 calcium carbonate (δ13CVPDB = +1.95 mUr, where milliurey = 0.001 = 1 ‰), LSVEC lithium carbonate (δ13CVPDB = −46.6 mUr), and IAEA-N-1 ammonium sulfate (δ15NAir = +0.43 mUr) and USGS32 potassium nitrate (δ15N = +180 mUr exactly) by on-line combustion, continuous-flow isotope-ratio mass spectrometry, and off-line dual-inlet isotope-ratio mass spectrometry.ResultsUSGS41a is isotopically homogeneous; the reproducibility of δ13C and δ15N is better than 0.07 mUr and 0.09 mUr, respectively, in 200-μg amounts. It has a δ13C value of +36.55 mUr relative to VPDB and a δ15N value of +47.55 mUr relative to N2 in air. USGS41 was found to be hydroscopic, probably due to the presence of pyroglutamic acid. Experimental results indicate that the chemical purity of USGS41a is substantially better than that of USGS41.ConclusionsThe new isotopic reference material USGS41a can be used with USGS40 (having a δ13CVPDB value of −26.39 mUr and a δ15NAir value of −4.52 mUr) for (i) analyzing local laboratory isotopic reference materials, and (ii) quantifying drift with time, mass-dependent isotopic fractionation, and isotope-ratio-scale contraction for isotopic analysis of biological and organic materials. Published in 2016. This article is a U.S. Government work and is in the public domain in the USA.

  5. Reasons for Discontinuing Study: The Case of Mature Age Female Students with Children.

    Science.gov (United States)

    Scott, Catherine; And Others

    1996-01-01

    A study of 118 adult women students, with children, in 3 Australian universities found 3 major factors in withdrawal: socioeconomic class (lack of family support for mother's study, lack of money, domestic responsibilities, lack of needed skills); nontraditional major (economics, business, law); and age (younger students because of family or…

  6. Summer Students

    CERN Multimedia

    2005-01-01

    SUMMER STUDENT LECTURE PROGRAMME Main Auditorium, bldg. 500 DATE TIME LECTURER TITLE Monday 1 August 09:15 - 10:00 P. WELLS The Higgs Saga at LEP 10:15 - 11:00 E. KIRITSIS Beyond the Standard Model (1/4) 11:15 - 12:00 G. COWAN Introduction to Statistics (1/3) 12:00 Discussion Session Tuesday 2 August 09:15 - 11:00 E. KIRITSIS Beyond the Standard Model (2-3/4) 11:15 - 12:00 G. COWAN Introduction to Statistics (2/3) 12:00 Discussion Session Wednesday 3 August 09:15 - 10:00 G. COWAN Introduction to Statistics (3/3) 10:15 - 11:00 E. KIRITSIS Beyond the Standard Model (4/4) 11:15 - 12:00 K. JAKOBS Physics at Hadronic Colliders (1/4) 12:00 Discussion Session Thursday 4 August 09:15 - 11:00 K. JAKOBS Physics at Hadronic Colliders (2-3/4) 11:15 - 12:00 A. WEINSTEIN Gravitation Waves 12:00 Discussion Session 16:30 - 18:00 Poster Session Friday 5 August 09:15 - 11:00 A. Höcker CP Violation (1-2/4) 11:15 - 12:00 K. JA...

  7. Summer Students

    CERN Multimedia

    2005-01-01

    SUMMER STUDENT LECTURE PROGRAMME Main Auditorium, bldg. 500 DATE TIME LECTURER TITLE Monday 11 July 09:15 - 10:00 L. Di Lella (CERN) Introduction to Particle Physics (4/4) 10:15 - 11:00 P. Chomaz (GANIL / CERN) Introduction to Nuclear Physics (3/3) 11:15 - 12:00 G. ROLANDI (CERN) How an experiment is designed (2/2) 12:00 Discussion Session Tuesday 12 July  09:15 - 11:00 O. BrÜning (CERN) Accelerators (1-2/5) 11:15 - 12:00 O. ULLALAND (CERN) Detectors (1/5) 12:00 Discussion Session Wednesday 13 July 09:15 - 10:00 O. BrÜning (CERN) Accelerators (3/5) 10:15 - 11:00 R. LANDUA (CERN) Antimatter in the Lab (1/2) 11:15 - 12:00 O. ULLALAND (CERN) Detectors (2/5) 12:00 Discussion Session Thursday 14 July 09:15 - 10:00 O. ULLALAND (CERN) Detectors (3/5) 10:15 - 11:00 G. ROLANDI (CERN) Antimatter in the Lab (2/2) 11:15 - 12:00 O. BrÜning (CERN) Accelerators (4/5) 12:00 Discussion Session Friday 1...

  8. Prevalence of Depression among Undergraduate Students: Gender and Age Differences

    Directory of Open Access Journals (Sweden)

    Leila Ghaedi

    2014-06-01

    Full Text Available Depressive disorders are the most typical disease affecting many different factors of humanity. University students may be at increased risk of depression owing to the pressure and stress they encounter. Therefore, the purpose of this study is comparing the level of depression among male and female athletes and non-athletes undergraduate student of private university in Esfahan, Iran. The participants in this research are composed of 400 male and female athletes as well as no-athletes Iranian undergraduate students. The Beck depression test (BDI was employed to measure the degree of depression. T-test was used to evaluate the distinction between athletes and non-athletes at P≤0.05. The ANOVA was conducted to examine whether there was a relationship between level of depression among non-athletes and athletes. The result showed that the prevalence rate of depression among non-athlete male undergraduate students is significantly higher than that of athlete male students. The results also presented that level of depression among female students is much more frequent compared to males. This can be due to the fatigue and lack of energy that are more frequent among female in comparison to the male students. Physical activity was negatively related to the level of depression by severity among male and female undergraduate students. However, there is no distinct relationship between physical activity and level of depression according to the age of athlete and nonathlete male and female undergraduate students. This study has essential implications for clinical psychology due to the relationship between physical activity and prevalence of depression.

  9. 1H, 13C and 15N chemical shift assignments of the thioredoxin from the obligate anaerobe Desulfovibrio vulgaris Hildenborough.

    Science.gov (United States)

    Garcin, Edwige B; Bornet, Olivier; Pieulle, Laetitia; Guerlesquin, Françoise; Sebban-Kreuzer, Corinne

    2011-10-01

    Thioredoxins are ubiquitous key antioxidant enzymes which play an essential role in cell defense against oxidative stress. They maintain the redox homeostasis owing to the regulation of thiol-disulfide exchange. In the present paper, we report the full resonance assignments of (1)H, (13)C and (15)N atoms for the reduced and oxidized forms of Desulfovibrio vulgaris Hildenborough thioredoxin 1 (Trx1). 2D and 3D heteronuclear NMR experiments were performed using uniformly (15)N-, (13)C-labelled Trx1. Chemical shifts of 97% of the backbone and 90% of the side chain atoms were obtained for the oxidized and reduced form (BMRB deposits with accession number 17299 and 17300, respectively).

  10. Student Ideas About Cosmological Concepts: Age, Expansion, and the Big Bang

    Science.gov (United States)

    Trouille, Laura; Coble, K.; Camarillo, C.; Bailey, J.; Nickerson, M.; Cochran, G.; Hayes, V.; McLin, K.; Cominsky, L.

    2012-05-01

    Students enter introductory astronomy classes with ideas about the universe that are often misaligned with accepted scientific beliefs. In this presentation we will describe the results from a multi-semester study of urban minority students’ ideas in an introductory astronomy course. We use in-depth student interviews, homework assignments, lab responses, and exams to identify pre-instructional ideas. We also examine the resilience of alternate conceptions to modification through instruction. In this presentation we focus on students’ ideas with regards to the Big Bang, the age of the Universe, and the expansion of the Universe over time. We find that a significant fraction of students enter our astronomy courses with alternate conceptions, including that the Big Bang refers to an explosion from a small, single point in space, that there is no evidence for the Big Bang, that there is a center to our Universe, that the Universe expands into pre-existing matter, and that the Universe has either a much smaller or much larger age than its accepted age. Some of these alternate conceptions are relatively easy to overcome through active learning (for example, whether there is a center to the Universe), while others are more resistant to change (for example, whether the Universe expands into pre-existing matter). Also see our presentations on student ideas of structure and distances (Camarillo et al.) as well as the overview of our methodology (Coble et al.). This work was supported by NASA ROSES E/PO Grant #NNX1OAC89G, as well as by the Illinois Space Grant Consortium and National Science Foundation CCLI Grant #0632563 at Chicago State University and the Fermi E/PO program at Sonoma State University.

  11. Clinical-scale investigation of stable isotopes in human blood: delta13C and delta15N from 406 patients at the Johns Hopkins Medical Institutions.

    Science.gov (United States)

    Kraft, Rebecca A; Jahren, A Hope; Saudek, Christopher D

    2008-11-01

    Objective chemical biomarkers are needed in clinical studies of diet-related diseases to supplement subjective self-reporting methods. We report on several critical experiments for the development of clinically legitimate dietary stable isotope biomarkers within human blood. Our examination of human blood revealed the following: (1) Within blood clot and serum from anonymous individuals (201 males, 205 females) we observed: mean serum delta13C = -19.1 +/- 0.8 per thousand (standard deviation, SD); clot, -19.3 +/- 0.8 per thousand (SD); range = -15.8 per thousand to -23.4 per thousand. Highly statistically significant differences are observed between clot and serum, males and females for both clot and serum. For 15N (n = 206), mean serum = +8.8 +/- 0.5 per thousand (SD); clot +7.4 +/- 0.4 per thousand (SD); range = +6.3 per thousand to +10.5 per thousand. Blood serum is enriched in 15N relative to blood clot by +1.4 per thousand on average, which may reflect differing protein amino acid content. Serum nitrogen is statistically significantly different for males and females, however, clot shows no statistical difference. (2) Relative to clot, capillary blood is marginally different for 13C, but not 15N. Clot 13C is not significantly different from serum; however, it is depleted in 15N by 1.5 per thousand relative to serum. (3) We assessed the effect of blood additives (sodium fluoride and polymerized acrylamide resin) and laboratory process (autoclaving, freeze drying) commonly used to preserve or prepare venous blood. On average, no alteration in delta13C or delta15N is detected compared with unadulterated blood from the same individual. (4) Storage of blood with and without the additives described above for a period of up to 115 days exhibits statistically significant differences for 13C and 15N for sodium fluoride. However, storage for unadulterated blood and blood preserved with polymerized acrylamide resin does not change the delta13C or delta15N isotopic

  12. Sex Survey about university students of UPF (from 20 to 27 years old

    Directory of Open Access Journals (Sweden)

    Carmen Maté

    2013-08-01

    Full Text Available The purpose of the present survey was to assess the level of sexual knowledge, attitudes and practice of university students, adult young people from 20 to 27 years old and to identify if there was any significant difference in terms of age and sexual activity with other surveys. The survey was undertaken in which data were collected from 838 students who attended the third and four course of their graduate in Humanities. Differences between answers by sex were tested using Pearson’s χ2 test. The study established that behaviour, knowledge, attitudes and practice of the universitary students vary by sex in some regards. The fi rst sexual relationships is around they have 15,4 years old and no statistically significant difference was found between sex. The average of the starter interesting about sex is around 13,5 years old and a statistically signifi cant difference was found between sex, the average of boys is 12,7 years old and girls 13,7. People who were sexually active are satisfi ed and show is so important to their wellbeing. Majority use contraceptive methods in the last relationship and the same percentage use the condom in order to avoid sexually transmitted diseases. The study confirmed that there are 21% the students don’t use any method to avoid sexually transmitted diseases. Our conclusion is both, the knowledge and attitudes of students necessarily required appropriate sex education in the secondary school.

  13. ISOTOPES, PLANTS, AND RESERVOIR EFFECTS : CASE STUDY FROM THE CASPIAN STEPPE BRONZE AGE

    NARCIS (Netherlands)

    Shishlina, N.; Zazovskaya, E.; van der Plicht, J.; Sevastyanov, V.; Boaretto, E.; Rebollo Franco, N.R.

    2012-01-01

    Bronze Age human and animal bone collagen from several steppe Bronze Age cultures (i.e. Early Catacomb, East and West Manych Catacomb, and Lola cultures) shows large variations in delta C-13 and delta N-15 values. In general, we observed that the older the sample, the lower the delta C-13 and delta

  14. Predicting the Motivation in College-Aged Learning Disabled Students Based on the Academic Motivation Scale

    Science.gov (United States)

    Luna, Alberto D.

    2013-01-01

    Given the paucity of research on factors associated with motivation in learning disabled college students, the present study investigated the motivation levels in college students with learning disabilities. The Academic Motivation Scale (AMS) has been validated cross-nationally and across all educational age groups of students having various…

  15. Summer Students

    CERN Multimedia

    2005-01-01

    SUMMER STUDENT LECTURE PROGRAMME Main Auditorium, bldg. 500 DATE TIME LECTURER TITLE Monday 18 July 09:15 - 11:00 G. ROSS Fundamental concepts in Particle Physics (1-2/6) 11:15 - 12:00 N. PALANQUE-DELABROUILLE Astroparticle Physics (1/3) 12:00 Discussion Session Tuesday 19 July 09:15 - 10:00 G. ROSS Fundamental concepts in Particle Physics (3/6) 10:15 - 12:00 N. PALANQUE-DELABROUILLE Astroparticle Physics (2-3/3) 12:00 Discussion Session Wednesday 20 July 09:15 - 10:00 G. ROSS Fundamental concepts in Particle Physics (4/6) 10:15 - 11:00 F. RADEMAKERS ROOT 11:15 - 12:00 L. ROSSI Super-conducting magnet technology for particle accelerators and detectors 12:00 Discussion Session Thursday 21 July 09:15 - 10:00 G. ROSS Fundamental concepts in Particle Physics (5/6) 10:15 - 12:00 C. DE LA TAILLE Introduction to Electronics (1-2/3) 12:00 Discussion Session Friday 22 July 09:15 - 10:00 C. DE LA TAILLE Introduction to Electronics (3/3) 10:15 -...

  16. The Structure of Working Memory from 4 to 15 Years of Age

    Science.gov (United States)

    Gathercole, Susan E.; Pickering, Susan J.; Ambridge, Benjamin; Wearing, Hannah

    2004-01-01

    The structure of working memory and its development across the childhood years were investigated in children 4-15 years of age. The children were given multiple assessments of each component of the A. D. Baddeley and G. Hitch (1974) working memory model. Broadly similar linear functions characterized performance on all measures as a function of…

  17. Indicators of prescribing quality in drug utilisation research : report of a European meeting (DURQUIM, 13-15 May 2004)

    NARCIS (Netherlands)

    Hoven, JL; Haaijer-Ruskamp, FM; Vander Stichele, RH

    An invitational expert meeting on indicators of prescribing quality was held on 13-15 May 2004, bringing together-from 19 European countries, the US, Canada, and Australia-40 researchers specialized in the development and application of indicators. The meeting was organized by the European Drug

  18. Sexual behavior of school-aged adolescents in the city of Goiânia, Goiás.

    Science.gov (United States)

    Sasaki, Reinaldo Satoru Azevedo; de Souza, Márcia Maria; Leles, Cláudio Rodrigues; Malta, Deborah Carvalho; Sardinha, Luciana Monteiro Vasconcelos; Freire, Maria do Carmo Matias

    2014-01-01

    To investigate the characteristics of sexual behavior in school-aged adolescents and possible differences regarding sex and type of school. Cross-sectional study using data from the National Adolescent School-based Health Survey (PeNSE) 2009, carried out by the Brazilian Ministry of Health, in partnership with the Brazilian Institute of Geography and Statistics (IBGE). The sample consisted of 3,099 9th graders living in Goiânia, State of Goiás, Brazil, mostly aged between 13 to 15 years old, who answered a self-applicable questionnaire on risk and protective health factors. The Rao-Scott test was used in the statistical analysis, considering the complex sample design. The prevalence of sexual intercourse was of 26.5% (95%CI 23.8 - 29.4) at least once in life and of 18.5% (95%CI 16.5 - 20.8) in the last year. Both behaviors were more frequent among male students and among those attending public schools. Most of the respondents had their first intercourse at the age of 13 or younger, with up to 3 partners. They had also used a pregnancy prevention method in the last intercourse, and received guidance on prevention at school. The age of the first intercourse was earlier and the number of partners was higher among male students. More females and those attending public schools reported having received information on pregnancy prevention. Guidance on STD/AIDS was also more frequent in public schools. Results showed a need for health education measures involving education and health professionals, as well as parents, to reduce the discrepancies found regarding sex and type of school.

  19. 15-Lipoxygenase metabolites of α-linolenic acid, [13-(S)-HPOTrE and 13-(S)-HOTrE], mediate anti-inflammatory effects by inactivating NLRP3 inflammasome

    Science.gov (United States)

    Kumar, Naresh; Gupta, Geetika; Anilkumar, Kotha; Fatima, Naireen; Karnati, Roy; Reddy, Gorla Venkateswara; Giri, Priyanka Voori; Reddanna, Pallu

    2016-01-01

    The ratio of ω-6 to ω-3 polyunsaturated fatty acids (PUFAs) appears to be critical in the regulation of various pathophysiological processes and to maintain cellular homeostasis. While a high proportion of dietary intake of ω-6 PUFAs is associated with various inflammatory disorders, higher intake of ω-3 PUFAs is known to offer protection. It is now well established that beneficial effects of ω-3 PUFAs are mediated in part by their oxygenated metabolites mainly via the lipoxygenase (LOX) and cyclooxygenase (COX) pathways. However, the down-stream signaling pathways that are involved in these anti-inflammatory effects of ω-3 PUFAs have not been elucidated. The present study evaluates the effects of 15-LOX metabolites of α-linolenic acid (ALA, ω-3 PUFA) on lipopolysaccharide (LPS) induced inflammation in RAW 264.7 cells and peritoneal macrophages. Further, the effect of these metabolites on the survival of BALB/c mice in LPS mediated septic shock and also polymicrobial sepsis in Cecal Ligation and Puncture (CLP) mouse model was studied. These studies reveal the anti-inflammatory effects of 13-(S)-hydroperoxyoctadecatrienoic acid [13-(S)-HPOTrE] and 13-(S)-hydroxyoctadecatrienoic acid [13-(S)-HOTrE] by inactivating NLRP3 inflammasome complex through the PPAR-γ pathway. Additionally, both metabolites also deactivated autophagy and induced apoptosis. In mediating all these effects 13-(S)-HPOTrE was more potent than 13-(S)-HOTrE. PMID:27535180

  20. Tetrasomy 15q11-q13 identified by fluorescence in situ hybridization in a patient with autistic disorder Identificação de tetrassomia 15q11-q13 por hibridação in situ fluorescente em uma paciente com distúrbio autístico

    Directory of Open Access Journals (Sweden)

    Ana Elizabete Silva

    2002-06-01

    Full Text Available We report a female child with tetrasomy of the 15q11-q13 chromosomal region, and autistic disorder associated with mental retardation, developmental problems and behavioral disorders. Combining classical and molecular cytogenetic approaches by fluorescence in situ hybridization technique, the karyotype was demonstrated as 47,XX,+mar.ish der(15(D15Z1++,D15S11++,GABRB3++,PML-. Duplication of the 15q proximal segment represents the most consistent chromosomal abnormality reported in association with autism. The contribution of the GABA receptor subunit genes, and other genes mapped to this region, to the clinical symptoms of the disease is discussed.Relatamos uma criança do sexo feminino com tetrassomia da região cromossômica 15q11-q13 e distúrbio autístico associado com retardo mental, problemas de desenvolvimento e distúrbios comportamentais. A combinação de metodologias da citogenética clássica e molecular pela técnica de hibridação in situ fluorescente, demonstrou o cariótipo como 47,XX,+mar.ish der(15 (D15Z1++,D15S11++,GABRB3++,PML. Duplicação do segmento 15q proximal representa a mais consistente anomalia cromossômica relatada em associação com autismo. A contribuição dos genes das subunidades do recepetor GABA, assim como outros genes mapeados nessa região, para os sintomas clínicos da doença é discutida.

  1. Determination of δ13C, δ15N, or δ34S by isotope-ratio-monitoring mass spectrometry using an elemental analyzer

    Science.gov (United States)

    Johnson, Craig A.; Stricker, Craig A.; Gulbransen, Cayce A.; Emmons, Matthew P.

    2018-02-14

    This report describes procedures used in the Geology, Geophysics, and Geochemistry Science Center of the U.S. Geological Survey in Denver, Colorado, to determine the stable-isotope ratios 13C/12C, 15N/14N, and 34S/32S in solid materials. The procedures use elemental analyzers connected directly to gas-source isotope-ratio mass spectrometers. A different elemental–analyzer–mass-spectrometer system is used for 13C/12C and 15N/14N than is used for 34S/32S to accommodate differences in reagents, catalysts, and instrument settings.

  2. Relationship between dental caries and metabolic syndrome among 13 998 middle-aged urban Chinese.

    Science.gov (United States)

    Cao, Xia; Wang, Dongliang; Zhou, Jiansong; Yuan, Hong; Chen, Zhiheng

    2017-04-01

    The association between dental caries and metabolic syndrome (MetS) is inconsistent. The aim of the present study was to assess the relationship between dental caries and MetS and its components in a middle-aged Chinese population. A cross-sectional analysis was performed of 13 998 participants aged 45-65 years undergoing a health check during 2013-14. An index variable of decayed, missing, and filled teeth (DMFT) was calculated. Logistic regression was used to estimate odds ratios (ORs) and 95 % confidence intervals (CIs) after adjustment for sex, age, education level, dietary habits, alcohol use, smoking, physical activity, and periodontitis. Of the 13 998 participants, 6164 had dental caries and 7834 did not; 3571 had MetS, whereas 10 427 did not. Participants with severe caries showed a higher prevalence of MetS, abdominal obesity, elevated blood pressure, dyslipidemia, and hyperglycemia than those with mild or no caries (all P dental caries and those with two or more DMFT were 1.12 (95 % CI 1.14-1.74) and 1.09 (95 % CI, 0.89-1.21), respectively (P trend  caries were associated with MetS among subjects with hyperglycemia (OR 1.14 [95%CI, 0.98-1.34]; P caries and abdominal obesity, hypertriglyceridemia, low high-density lipoprotein cholesterol, and elevated blood pressure (adjusted ORs [95 % CIs] 0.98 [0.82-1.16], 1.01 [0.85-1.19], 0.84 [0.70-1.00], and 0.96 [0.86-1.13], respectively; all P > 0.05). Dental caries were associated with MetS among middle-aged Chinese in the present study. © 2016 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd.

  3. Oral Hygiene and Handwashing Practices among Middle School Students in 15 Latin American and Caribbean Countries.

    Science.gov (United States)

    McKittrick, T R; Jacobsen, K H

    2015-06-01

    To examine the relationship between infrequent toothbrushing and infrequent handwashing among middle school students from 15 Latin American and Caribbean countries (Antigua and Barbuda, Argentina, British Virgin Islands, Cayman Islands, Costa Rica, Grenada, Guatemala, Guyana, Peru, Saint Kitts and Nevis, Saint Lucia, Saint Vincent and Grenadines, Suriname, Trinidad and Tobago, and Uruguay). A secondary analysis was done of nationally-representative data from 33 174 middle school students who participated in the Global School-based Student Health Survey (GSHS) between 2006 and 2011. In all 15 countries, the association between rarely brushing or cleaning teeth and rarely handwashing after using the toilet was significant for both boys and girls. The pooled odds ratio for this association was 6.7 (5.8, 7.7). Healthcare providers who notice signs of poor dental hygiene or infrequent bathing in adolescents should consider providing comprehensive hygiene education to their patients, since infrequent oral and body hygiene behaviours tend to co-exist and both are threats to health.

  4. Disease duration and age influence CARD15 expression in Crohn’s disease

    Directory of Open Access Journals (Sweden)

    Elżbieta Poniewierka

    2016-01-01

    Full Text Available One of the susceptibility genes in Crohn’s disease (CD is CARD15. Our study examined the relationship between peripheral CARD15 expression and phenotype and duration of CD, treatment methods and inflammatory indices. Sixty patients with CD and 30 healthy volunteers as controls were enrolled in the study. Total RNA was isolated from peripheral blood mononuclear cells (PBMCs with E.Z.N.A. Total RNA Kit (Omega Bio-tek then quantitative real-time PCR was performed on the ABI Prism 7900 HT Real-Time PCR System. CARD15 gene expression in PBMCs in CD was significantly higher than in the control group. The highest level of gene expression was found in CD patients in the fourth decade of life. The mRNA level of the CARD15 gene was higher in patients with disease duration between 12 and 60 months. A positive correlation was found between erythrocyte sedimentation rate (ESR and gene expression level. Gene expression increased with increasing level of C-reactive protein and ESR, but it was not statistically significant. CARD15 expression significantly decreased in CD patients treated with anti-TNFα agents compared to azathioprine or steroid treatment groups. Expression of the CARD15 gene in Crohn›s disease is higher than in healthy individuals. Disease duration and age of patients seem to be the most important factors influencing CARD15 expression.

  5. Effect of ageing on the microstructural stability of cold-worked titanium-modified 15Cr-15Ni-2.5Mo austenitic stainless steel

    International Nuclear Information System (INIS)

    Venkadesan, S.; Bhaduri, A.K.; Rodriguez, P.; Padmanabhan, K.A.

    1992-01-01

    A titanium-modified 15Cr-15Ni-2.5Mo austenitic stainless steel conforming to ASTM A 771 (UNS S 38660), commercially called Alloy D9, is being indigenously developed for application as material for the fuel clad and the hexagonal wrapper for fuel subassemblies of the Prototype Fast Breeder Reactor. As this material would be used in the cold-worked condition and would be subjected to prolonged exposure to elevated service temperatures, the effect of ageing on the microstructural stability was studied as a function of the amount of cold work. The material was given 2.5-30% prior cold work and then aged at temperatures in the range 923 to 1173 K for times ranging from 0.25 to 1000 h. Hardness measurements made before and after ageing were correlated with the Larson-Miller parameter to determine the highest stable prior cold-work level. Optical microscopy was used to study the microstructural changes. The influence of prolonged exposure for two and three years at the operating temperatures of clad and wrapper, on the elevated temperature tensile properties of a 20% prior cold-worked Alloy D9 was also studied through accelerated ageing treatments based on the present parametric approach. (orig.)

  6. Auto-inducing media for uniform isotope labeling of proteins with {sup 15}N, {sup 13}C and {sup 2}H

    Energy Technology Data Exchange (ETDEWEB)

    Guthertz, Nicolas [Institute of Cancer Research, Division of Structural Biology (United Kingdom); Klopp, Julia; Winterhalter, Aurélie; Fernández, César; Gossert, Alvar D., E-mail: alvar.gossert@novartis.com [Novartis Institutes for BioMedical Research (Switzerland)

    2015-06-15

    Auto-inducing media for protein expression offer many advantages like robust reproducibility, high yields of soluble protein and much reduced workload. Here, an auto-inducing medium for uniform isotope labelling of proteins with {sup 15}N, {sup 13}C and/or {sup 2}H in E. coli is presented. So far, auto-inducing media have not found widespread application in the NMR field, because of the prohibitively high cost of labeled lactose, which is an essential ingredient of such media. Here, we propose using lactose that is only selectively labeled on the glucose moiety. It can be synthesized from inexpensive and readily available substrates: labeled glucose and unlabeled activated galactose. With this approach, uniformly isotope labeled proteins were expressed in unattended auto-inducing cultures with incorporation of {sup 13}C, {sup 15}N of 96.6 % and {sup 2}H, {sup 15}N of 98.8 %. With the present protocol, the NMR community could profit from the many advantages that auto-inducing media offer.

  7. Impact of an Aging Simulation Game on Pharmacy Students’ Empathy for Older Adults

    Science.gov (United States)

    Kiersma, Mary E.; Yehle, Karen S.; Plake, Kimberly S.

    2015-01-01

    Objective. To evaluate changes in empathy and perceptions as well as game experiences among student pharmacists participating in an aging simulation game. Methods. First-year student pharmacists participated in an aging simulation game. Changes were measured pre/post-activity using the Kiersma-Chen Empathy Scale (KCES) and Jefferson Scale of Empathy – Health Professions Scale (JSE-HPS) for empathy and the Aging Simulation Experience Survey (ASES) for perceptions of older adults’ experiences and game experiences. Wilcoxon signed rank tests were used to determine changes. Results. One hundred fifty-six student pharmacists completed the instruments. Empathy using the KCES and JSE-HPS improved significantly. Of the 13 items in the ASES, 9 significantly improved. Conclusion. Simulation games may help students overcome challenges demonstrating empathy and positive attitudes toward elderly patients. PMID:26396274

  8. Influence of age, sex, and race on college students' exercise motivation of physical activity.

    Science.gov (United States)

    Egli, Trevor; Bland, Helen W; Melton, Bridget F; Czech, Daniel R

    2011-01-01

    The authors examined differences in exercise motivation between age, sex, and race for college students. Students from 156 sections of physical activity classes at a midsize university were recruited (n = 2,199; 1,081 men, 1,118 women) in 2005-2006 and volunteered to complete the Exercise Motivation Inventory. Quantitative, cross-sectional descriptive research design was employed. Significant differences were found in 3 of 14 exercise motivational subscales by age (affiliation, health pressures, and ill health avoidance) (p motivated by intrinsic factors (strength, competition, and challenge) (p motivations (p motivations in college-aged population by demographics were documented. Understanding these differences is important for college health professionals for programming strategies and promoting physical activity.

  9. Effects of climate on deer bone δ15N and δ13C: Lack of precipitation effects on δ15N for animals consuming low amounts of C 4 plants

    Science.gov (United States)

    Cormie, A. B.; Schwarcz, H. P.

    1996-11-01

    We have examined the relationship of bone collagen δ15N and δ13C to climatic variables, humidity, temperature, and amount of precipitation using fifty-nine specimens of North American white-tailed deer ( Odocoileus virginianus) from forty-six different locations. In previous studies of African mammals there was a significant correlation between bone collagen δ15N and local amount of precipitation. Results presented here similarly show an increase in δ15N with decreasing amount of precipitation but only for 25% of the animals, namely those consuming more than 10% C 4 plants. These animals also exhibited a significant correlation between δ13C and temperature which mirrors previous observations for grasses suggesting that these deer consume grasses during times of population and nutrient stress. In contrast, even in dry areas containing high proportions of C 4 grasses, the majority of the deer had consumed low amounts of C 4 plants and these deer did not have δ15N which correlate with amount of precipitation. Only when deer deviated from their normal feeding pattern by consuming C 4 plants or grasses did their δ15N correlate with amount of rainfall. For these animals, consumption of C 4 plants or grasses may signal conditions of water and nutrient stress. An increase in δ15N of bone collagen may result from combined effects from excretion of concentrated urine (to conserve water) and increased internal recycling of nitrogen (to conserve nitrogen).

  10. Is 8:30 a.m. Still Too Early to Start School? A 10:00 a.m. School Start Time Improves Health and Performance of Students Aged 13–16

    Directory of Open Access Journals (Sweden)

    Paul Kelley

    2017-12-01

    Full Text Available While many studies have shown the benefits of later school starts, including better student attendance, higher test scores, and improved sleep duration, few have used starting times later than 9:00 a.m. Here we report on the implementation and impact of a 10 a.m. school start time for 13 to 16-year-old students. A 4-year observational study using a before-after-before (A-B-A design was carried out in an English state-funded high school. School start times were changed from 8:50 a.m. in study year 0, to 10 a.m. in years 1–2, and then back to 8:50 a.m. in year 3. Measures of student health (absence due to illness and academic performance (national examination results were used for all students. Implementing a 10 a.m. start saw a decrease in student illness after 2 years of over 50% (p < 0.0005 and effect size: Cohen's d = 1.07, and reverting to an 8:50 a.m. start reversed this improvement, leading to an increase of 30% in student illness (p < 0.0005 and Cohen's d = 0.47. The 10:00 a.m. start was associated with a 12% increase in the value-added number of students making good academic progress (in standard national examinations that was significant (<0.0005 and equivalent to 20% of the national benchmark. These results show that changing to a 10:00 a.m. high school start time can greatly reduce illness and improve academic performance. Implementing school start times later than 8:30 a.m., which may address the circadian delay in adolescents' sleep rhythms more effectively for evening chronotypes, appears to have few costs and substantial benefits.

  11. Students' Age Difference of Confidence in Using Technology for Learning in Higher Education

    Science.gov (United States)

    Yau, Hon Keung; Cheng, Alison Lai Fong

    2012-01-01

    Some past studies find that older students have more confidence in using technology for learning than younger students but some other studies find the opposite result. However, it is found that there are a few researches studying on the age difference in the perception of using technology for learning in Hong Kong. Therefore, the aim of the study…

  12. Drinking, cannabis use and driving among Ontario students.

    Science.gov (United States)

    Adlaf, Edward M; Mann, Robert E; Paglia, Angela

    2003-03-04

    Little is known about the risk of injury among adolescents who drive after the use of alcohol or cannabis or ride in cars driven by drunk drivers. We examined data from self-administered interviews with 1846 students in grades 7 to 13 who participated in the 2001 Ontario Student Drug Use Survey about their experiences related to alcohol, cannabis and driving during the 12 months preceding the survey. In all, 31.9% of the students reported being a passenger in a car driven by a drunk driver; of the students in grades 10 to 13 who had a driver's licence, 15.1% reported driving within an hour after consuming 2 or more drinks, and 19.7% reported driving within an hour after using cannabis. Our study shows that a sizeable proportion of adolescents are exposed to alcohol- and drug-related driving risks.

  13. Relationship between sleep and mood states among student-athlete ...

    African Journals Online (AJOL)

    This study aims to examine the relationship between sleep and mood states on student-athlete. The respondent consists of 89 student-athletes from MajlisSukanNegeri, Perak. There were 53 male respondent (59.3%) and 36 female respondent (40.4%). These respondent were range from age 13 to 21 years old are chosen ...

  14. Culture and diet among Chinese American children aged 9–13 years: A qualitative study

    Science.gov (United States)

    This study examined Chinese American children's behaviors, food preferences, and cultural influences on their diet. Qualitative individual interviews were conducted with twenty-five Chinese American children aged 9-13 years in community centers and Chinese schools in Houston, TX using constructs fro...

  15. The Relative Age Effect and Its Influence on Academic Performance.

    Science.gov (United States)

    Navarro, Juan-José; García-Rubio, Javier; Olivares, Pedro R

    2015-01-01

    The policy of school organisation for grouping students in the same academic year is based on date of birth. The differences in the experiences and maturation of older students involve a relatively better performance in academic settings, which is known as the relative age effect (RAE). This effect is more important the younger the student is. The goal of this study is to identify the connections of influence that RAE, socioeconomic status (SES), and type of institution have on academic performance in a school population of eighth graders. The study is based on a population-based, representative sample of 15,234 8th graders (50.4% female; average age = 13.61 years) in the 2011 National System of Quality Assessment in Education Survey (SIMCE) from Chile. The SIMCE for global academic performance consists of 4 tests: reading, mathematics, social studies, and science. All tests consist of multiple-choice and closed questions. In addition, in order to have the information of general academic performance, an extra variable expressing the average score of each student was created. Also, the SIMCE includes additional variables for the evaluation process such as SES or type of school. Students were assigned to one of five age groups in terms of date of birth (G1, G2, G3, G4, and G5), in which students belonging to G1 are the oldest and students belonging to G5 are the youngest. The results achieved in the structural equation modelling indicate a good global fit. Individual relationships show significant effects of the three variables observed on academic performance, although SES received the highest values. The influence of RAE took place both in the full sample and sub-samples composed according to the SES and academic performance, showing higher values for students with lower scores. Although the influence of RAE decreases when SES is controlled, its effect is still significant and contributes to additionally explain the performance. The RAE remains, even with residual

  16. The Relative Age Effect and Its Influence on Academic Performance.

    Directory of Open Access Journals (Sweden)

    Juan-José Navarro

    Full Text Available The policy of school organisation for grouping students in the same academic year is based on date of birth. The differences in the experiences and maturation of older students involve a relatively better performance in academic settings, which is known as the relative age effect (RAE. This effect is more important the younger the student is. The goal of this study is to identify the connections of influence that RAE, socioeconomic status (SES, and type of institution have on academic performance in a school population of eighth graders.The study is based on a population-based, representative sample of 15,234 8th graders (50.4% female; average age = 13.61 years in the 2011 National System of Quality Assessment in Education Survey (SIMCE from Chile. The SIMCE for global academic performance consists of 4 tests: reading, mathematics, social studies, and science. All tests consist of multiple-choice and closed questions. In addition, in order to have the information of general academic performance, an extra variable expressing the average score of each student was created. Also, the SIMCE includes additional variables for the evaluation process such as SES or type of school. Students were assigned to one of five age groups in terms of date of birth (G1, G2, G3, G4, and G5, in which students belonging to G1 are the oldest and students belonging to G5 are the youngest.The results achieved in the structural equation modelling indicate a good global fit. Individual relationships show significant effects of the three variables observed on academic performance, although SES received the highest values. The influence of RAE took place both in the full sample and sub-samples composed according to the SES and academic performance, showing higher values for students with lower scores. Although the influence of RAE decreases when SES is controlled, its effect is still significant and contributes to additionally explain the performance.The RAE remains, even

  17. Il Concetto di Infinito nell'Intuizione Matematica (Concept of Infinity in Mathematical Intuition).

    Science.gov (United States)

    Ferrari, E.; And Others

    1995-01-01

    Investigated the acquisition and maturation of the infinity concept in mathematics of students ages 13-15. Found the infinity concept is learned by students only when provided with appropriate guidance. (Author/MKR)

  18. "I Ain't Changing Anything": A Case-Study of Successful Generation 1.5 Immigrant College Students' Writing

    Science.gov (United States)

    Riazantseva, Anastasia

    2012-01-01

    The purpose of this case-study was to understand the relationship between success in college and L2 academic writing of three Generation 1.5 Russian-speaking middle-class college students and to describe the factors that could have contributed to the levels of academic literacy that these students developed. The following research questions were…

  19. Do Parents’ Exercise Habits Predict 13–18-Year-Old Adolescents’ Involvement in Sport?

    Science.gov (United States)

    Sukys, Saulius; Majauskienė, Daiva; Cesnaitiene, Vida J.; Karanauskiene, Diana

    2014-01-01

    This study examined links between parents’ exercise habits and adolescents’ participation in sports activities, considering the aspects of gender and age. It was hypothesized that regular exercise by both parents would be related to children’s involvement in sport regardless of their gender and age. Moreover, it was hypothesized that children’s sports activities would be more strongly related to their father’s exercise activities. The study also examined the links between parents’ exercise habits and children’s motivation for sports. It was hypothesized that competition motives would be more important for children whose parents exercised regularly. The research sample included 2335 students from the seventh (n = 857), ninth (n = 960) and eleventh (n = 518) grades of various Lithuanian schools. The study used a questionnaire survey method, which revealed the links between parents’ exercise habits and their children’s participation in sport. Assessment of data for girls and boys showed that daughters’ participation in sport could be predicted by both their fathers’ and mothers’ exercise habits, but sons’ sports activities could be predicted only by the regular physical activities of their fathers. The assessment of children’s sporting activities according to age revealed links between parental exercising and the engagement of older (15–16 years old), but not younger adolescents (13–14 years old). Analysis of sports motivation showed that competition motives were more important for boys than for girls. Fitness, well-being and appearance motives were more important for older adolescents (15–18 years old), while competition motives were more important for younger adolescents (13–14 years old). Research revealed the relationship between children’s sport motives and fathers’ exercise habits, while examination of mothers’ exercise revealed no difference. Key points Parental exercising significantly predicts adolescents

  20. Diet-tissue stable isotope (Δ13C and Δ15N) discrimination factors for multiple tissues from terrestrial reptiles

    OpenAIRE

    Steinitz, R; Lemm, JM; Pasachnik, SA; Kurle, CM

    2016-01-01

    Copyright © 2015 John Wiley & Sons, Ltd. Rationale Stable isotope analysis is a powerful tool for reconstructing trophic interactions to better understand drivers of community ecology. Taxon-specific stable isotope discrimination factors contribute to the best use of this tool. We determined the first Δ 13 C and Δ 15 N values for Rock Iguanas (Cyclura spp.) to better understand isotopic fractionation and estimate wild reptile foraging ecology. Methods The Δ 13 C and Δ 15 N values between di...

  1. North Atlantic ecosystem shifts revealed by cod otolith δ15N and δ13C chronologies

    DEFF Research Database (Denmark)

    Pedersen, Jens Brøgger; Nielsen, Jens Munk; Steingrund, Petur

    . To study the link between environmental changes and ecosystem trophic structure we developed δ15N and δ13C chronologies by analyzing the organic matrix of cod otoliths from the Faroe Shelf cod population (1950-2010) and the Nuuk Fjord cod population (1927-2009). Significant correlations between δ15N & δ13C...... of organic matrix of otolith core material (Nuuk Fjord) and annual growth increments in Ocean Quahog (A. Islandica) shells will be included.......Changes in climate and exploitation have caused large fluctuations in the productivity of many North Atlantic cod populations and the collapse of many cod fisheries. These fluctuations are most likely due to a combined effect of physical processes and changes in ecosystem trophic structure...

  2. The fate of 13C15N labelled glycine in permafrost and surface soil at simulated thaw in mesocosms from high arctic and subarctic ecosystems

    DEFF Research Database (Denmark)

    Ravn, Nynne Marie Rand; Elberling, Bo; Michelsen, Anders

    2017-01-01

    Background and aim: Nutrient distribution and carbon fluxes upon spring thaw are compared in mesocosms from high arctic and subarctic ecosystems dominated by Cassiope tetragona or Salix hastata/Salix arctica, in order to evaluate the possibility of plant and microbial utilization of an organic...... compound in thawing permafrost and surface soil. Methods: Double labeled glycine (13C15N) was added to soil columns with vegetation and to permafrost. During thaw conditions ecosystem respiration 13C was measured and 13C and 15N distribution in the ecosystem pools was quantified one day and one month after...... glycine addition. Results: Near-surface soil microbes were more efficient in the uptake of intact glycine immediately upon thaw than plants. After one month plants had gained more 15N whereas microbes seemed to lose 15N originating from glycine. We observed a time lag in glycine degradation upon...

  3. [Effect of parental feeding behavior on eating behavior of children aged 1-3 years].

    Science.gov (United States)

    Liu, Hong-Hua; Chen, Jin-Jin

    2014-06-01

    To investigate the relationship between the eating behavior of children aged 1-3 years and parental feeding behavior and the effect of family status on feeding behavior. With stratified random sampling, 2 324 children aged 1-3 years were selected from Shanghai. Questionnaires were filled out by their parents or feeders to investigate the basic family information, parental feeding behavior, the eating behavior of children, and the basic information on children. The eating behavior of children was positively correlated with eating environment (r=0.223) and parental monitoring behavior (r=0.245) but negatively correlated with parental compulsive behavior (r=-0.264) (Pparental compulsive behavior (r=-0.569) but positively correlated with parental monitoring behavior (r=0.615) and eating environment (r=0.621). The emotional undereating of children was positively correlated with parental emotional feeding (r=0.259) and parental compulsive behavior (r=0.279). Parental monitoring behavior showed significant differences between different families (PParental feeding behavior is closely related to the eating behavior of children. Parental feeding behavior may vary across different family status.

  4. Complementary constraints from carbon (13C) and nitrogen (15N) isotopes on the glacial ocean's soft-tissue biological pump

    Science.gov (United States)

    Schmittner, A.; Somes, C. J.

    2016-06-01

    A three-dimensional, process-based model of the ocean's carbon and nitrogen cycles, including 13C and 15N isotopes, is used to explore effects of idealized changes in the soft-tissue biological pump. Results are presented from one preindustrial control run (piCtrl) and six simulations of the Last Glacial Maximum (LGM) with increasing values of the spatially constant maximum phytoplankton growth rate μmax, which accelerates biological nutrient utilization mimicking iron fertilization. The default LGM simulation, without increasing μmax and with a shallower and weaker Atlantic Meridional Overturning Circulation and increased sea ice cover, leads to 280 Pg more respired organic carbon (Corg) storage in the deep ocean with respect to piCtrl. Dissolved oxygen concentrations in the colder glacial thermocline increase, which reduces water column denitrification and, with delay, nitrogen fixation, thus increasing the ocean's fixed nitrogen inventory and decreasing δ15NNO3 almost everywhere. This simulation already fits sediment reconstructions of carbon and nitrogen isotopes relatively well, but it overestimates deep ocean δ13CDIC and underestimates δ15NNO3 at high latitudes. Increasing μmax enhances Corg and lowers deep ocean δ13CDIC, improving the agreement with sediment data. In the model's Antarctic and North Pacific Oceans modest increases in μmax result in higher δ15NNO3 due to enhanced local nutrient utilization, improving the agreement with reconstructions there. Models with moderately increased μmax fit both isotope data best, whereas large increases in nutrient utilization are inconsistent with nitrogen isotopes although they still fit the carbon isotopes reasonably well. The best fitting models reproduce major features of the glacial δ13CDIC, δ15N, and oxygen reconstructions while simulating increased Corg by 510-670 Pg compared with the preindustrial ocean. These results are consistent with the idea that the soft-tissue pump was more efficient

  5. Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders

    DEFF Research Database (Denmark)

    Isles, Anthony R; Ingason, Andrés; Lowther, Chelsea

    2016-01-01

    Duplications at 15q11.2-q13.3 overlapping the Prader-Willi/Angelman syndrome (PWS/AS) region have been associated with developmental delay (DD), autism spectrum disorder (ASD) and schizophrenia (SZ). Due to presence of imprinted genes within the region, the parental origin of these duplications m...

  6. Alcohol, tobacco and cannabis use: Do students with mild-intellectual disability mimic students in the general population?

    Science.gov (United States)

    Pacoricona Alfaro, Dibia Liz; Ehlinger, Virginie; Spilka, Stanislas; Ross, Jim; Sentenac, Mariane; Godeau, Emmanuelle

    2017-04-01

    Education policies encourage inclusion of students with mild-intellectual disability (mild-ID) in community/school life. However, such policies potentially increase exposure to substance use. This article examines tobacco, alcohol and cannabis use among French students enrolled in special units for students with disabilities (ULIS) at mainstream junior high schools compared to those of general population of the equivalent age; and explores factors associated with substance use among ULIS students, known to present mostly mild-ID. In 2014, a questionnaire adapted from the international HBSC/WHO study was administered to 700 ULIS students (mean-age 14.2). Comparative data were gathered from 7023 junior high-school students (mean-age 13.6) in the general population. Among students <14 years-old, tobacco and alcohol use rates were similar between ULIS and general population. For students ≥14, alcohol use remained comparable, while tobacco and cannabis use were higher in general population. Among ULIS students, low perceived health/life satisfaction, divorced/separated parents and high perceived academic demands were associated with tobacco use. Bullying, not liking school very much and attending schools outside a deprived area were associated with alcohol use. Having had sexual intercourse and not perceiving one's health as excellent were associated with cannabis use. Having dated was associated with using all three substances. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. NH3-SCR on Cu, Fe and Cu + Fe exchanged beta and SSZ-13 catalysts: Hydrothermal aging and propylene poisoning effects

    International Nuclear Information System (INIS)

    Wang, Aiyong; Wang, Yilin; Walter, Eric D.; Washton, Nancy M.

    2017-01-01

    Cu, Fe and Cu + Fe ion exchanged Beta and SSZ-13 catalysts were prepared by solution ion exchange using commercial NH 4 /Beta, and NH 4 /SSZ-13 that was prepared in-house. To study hydrothermal aging effects, Beta supported catalysts were aged hydrothermally at 700 °C and SSZ-13 supported catalysts were aged at 750 °C. In order to reveal the effects of Fe addition in the co-exchanged catalysts, these catalysts were characterized by means of powder X-ray diffraction (XRD), N 2 adsorption-desorption, electron paramagnetic resonance (EPR), 27 Al-nuclear magnetic resonance ( 27 Al-NMR) and propylene coking followed with temperature programmed reaction (TPR), and further tested with standard NH 3 -SCR with and without the presence of propylene. Collectively, the catalyst characterizations and reaction testing indicated minor beneficial effects of Fe addition in Cu,Fe/Beta, where NH 3 -SCR activity, N 2 selectivity and hydrothermal stability were all slightly improved. In contrast, Fe addition did not show apparent beneficial effects in low-temperature SCR for the Cu,Fe/SSZ-13 case. In conclusion, at elevated reaction temperatures, however, the presence of Fe indeed considerably improved NO conversion and N 2 selectivity for the hydrothermally aged Cu,Fe/SSZ-13 catalyst in the presence of propylene.

  8. Vitamin supplementation and related nutritional status in Thai children, aged 1-5 years.

    Science.gov (United States)

    Ratanachu-ek, Suntaree

    2014-06-01

    To evaluate the prevalence of vitamin supplementation in Thai children aged 1-5 years at Queen Sirikit National Institute of Child Health (QSNICH), parental knowledge of vitamins, practices, and related factors such as nutritional status in vitamin supplementation. A cross-sectional study was performed at the Well Child Clinic, QSNICH, from 1-31 May 2005. Five hundred parents of young children, aged 1-5 years were interviewed by using the questionnaire to obtain information regarding knowledge and practices of vitamin supplementation. Weight and length/height were measured and nutritional status was assessed using the Thai growth reference. The relationships among vitamin supplement, nutritional status, and other related factors were analyzed using Chi-square test. The p-value vitamin supplementation was 76%, including vitamin C 62%, multi-vitamin (MTV) 35%, and cod-liver oil 20%. Regarding parental knowledge of vitamins, 57% of them knew the health benefits but 74% did not know the toxic effects of vitamins. The reasons for vitamin supplementation were poor feeding 63%, under-weight 23% and unhealthy status 14%. Vitamins were obtained from over-the-counter 59%, health services 40%, and friends 1%. Vitamin supplementation was significantly higher in children over 2 years of age, whose parents knew the benefits of vitamins, and in those children with malnutrition. The prevalence of vitamin supplementation was high in malnourished children, over 2 years of age whose parents had knowledge about benefits of vitamins. Parents should be warned about the dangers of high dose of vitamin consumption.

  9. Structure of Student Time Management Scale (STMS)

    Science.gov (United States)

    Balamurugan, M.

    2013-01-01

    With the aim of constructing a Student Time Management Scale (STMS), the initial version was administered and data were collected from 523 standard eleventh students. (Mean age = 15.64). The data obtained were subjected to Reliability and Factor analysis using PASW Statistical software version 18. From 42 items 14 were dropped, resulting in the…

  10. Protective Effect of Human Leukocyte Antigen (HLA Allele DRB1*13:02 on Age-Related Brain Gray Matter Volume Reduction in Healthy Women

    Directory of Open Access Journals (Sweden)

    Lisa M. James

    2018-03-01

    Full Text Available Background: Reduction of brain volume (brain atrophy during healthy brain aging is well documented and dependent on genetic, lifestyle and environmental factors. Here we investigated the possible dependence of brain gray matter volume reduction in the absence of the Human Leukocyte Antigen (HLA allele DRB1*13:02 which prevents brain atrophy in Gulf War Illness (James et al., 2017. Methods: Seventy-one cognitively healthy women (32–69 years old underwent a structural Magnetic Resonance Imaging (sMRI scan to measure the volumes of total gray matter, cerebrocortical gray matter, and subcortical gray matter. Participants were assigned to two groups, depending on whether they lacked the DRB1*13:02 allele (No DRB1*13:02 group, N = 60 or carried the DRB1*13:02 allele (N = 11. We assessed the change of brain gray matter volume with age in each group by performing a linear regression where the brain volume (adjusted for total intracranial volume was the dependent variable and age was the independent variable. Findings: In the No DRB1*13:02 group, the volumes of total gray matter, cerebrocortical gray matter, and subcortical gray matter were reduced highly significantly. In contrast, none of these volumes showed a statistically significant reduction with age in the DRB1*13:02 group. Interpretation: These findings document the protective effect of DRB1*13:02 on age-dependent reduction of brain gray matter in healthy individuals. Since the role of this allele is to connect to matching epitopes of external antigens for the subsequent production of antibodies and elimination of the offending antigen, we hypothesize that its protective effect may be due to the successful elimination of such antigens to which we are exposed during the lifespan, antigens that otherwise would persist causing gradual brain atrophy. In addition, we consider a possible beneficial role of DRB1*13:02 attributed to its binding to cathepsin S, a known harmful substance in brain

  11. A Survey on Mental Health Status of Adult Population Aged 15 and above in the Province of Kohghilouyeh and Bouyerahmad, Iran.

    Science.gov (United States)

    Noorbala, Ahmad Ali; Bagheri Yazdi, Seyed Abbas; Faghihzadeh, Soghrat; Kamali, Koorosh; Faghihzadeh, Elham; Hajebi, Ahmad; Akhondzadeh, Shahin; Hormozpour, Mehdi; Aranpour, Hamdad

    2017-11-01

    This research aims to determine the mental health status of population aged 15 and over in the province of Kohghilouyeh and Bouyerahmad in 2015. The statistical population of this cross-sectional field survey consisted of residents of urban and rural areas of Kohghilouyeh and Bouyerahmad in Iran. An estimated sample size of 1200 people was chosen using systematic random cluster sampling. The access was provided by the contribution of Geographical Post Office of Yasuj, Dogonbadan, and Dehdasht cities. The General Health Questionnaire-28 (GHQ-28) was used as a screening tool for mental disorders. Data analysis in the current study was carried out using the SPSS-18 software. Using GHQ traditional scoring method, the results showed that 16.9% of the subjects showed to be at risk of mental disorders (20.1% of females and 13.4% of males). Urban areas (18.3%) were more at risk of mental disorders compared with rural residents (13.9%). Anxiety and somatization symptoms were more frequent than depression and social dysfunction among respondents. The obtained data revealed that the prevalence of mental disorders increased with age. The results also indicated that mental disorders were more common in certain subgroups; in particular women, those aged 65 years and above, the divorced and widowed, illiterate and retired adults. Our findings suggest that one sixth of the participants are at risk of developing mental disorders. Although the prevalence of these disorders has decreased from 26.2% to 16.9% between 1999 and 2015, it is still of great importance to further promote mental health policies and advocate psychological welfare of those suffering from mental disorders along with their re-empowerment.

  12. Residents with mild cognitive decline and family members report health students 'enhance capacity of care' and bring 'a new breath of life' in two aged care facilities in Tasmania.

    Science.gov (United States)

    Elliott, Kate-Ellen J; Annear, Michael J; Bell, Erica J; Palmer, Andrew J; Robinson, Andrew L

    2015-12-01

    Care provided by student doctors and nurses is well received by patients in hospital and primary care settings. Whether the same is true for aged care residents of nursing homes with mild cognitive decline and their family members is unknown. To investigate the perspectives of aged care residents with mild cognitive decline and their family members on interdisciplinary student placements in two residential aged care facilities (RACF) in Tasmania. A mixed methods design was employed with both qualitative and quantitative data collected. All participants were interviewed and completed a questionnaire on residents' quality of life, during or after a period of student placements in each facility (October-November, 2012). Qualitative data were coded for themes following a grounded theory approach, and quantitative data were analysed using SPSS. Twenty-one participants (13 residents and 8 family members) were recruited. Four themes were identified from the qualitative data and included (i) increased social interaction and facility vibrancy; (ii) community service and personal development, (iii) vulnerability and sensitivity (learning to care) and (iv) increased capacity and the confidence of enhanced care. Residents' quality of life was reported to be mostly good in the presence of the students, despite their high care needs. Residents with mild cognitive decline and their family members perceive a wide array of benefits of student provided care in RACFs including increased social interaction. Future quantitative research should focus on whether changes in care occur for residents as a result of student involvement. © 2014 The Authors Health Expectations Published by John Wiley & Sons Ltd.

  13. Curiosity killed the cat: No evidence of an association between cat ownership and psychotic symptoms at age 13 and 18 years in a UK general population cohort

    Science.gov (United States)

    Solmi, F.; Hayes, J.F; Lewis, G.; Kirkbride, J.B

    2018-01-01

    Background Congenital or early life infection with Toxoplasma Gondii has been implicated in schizophrenia aetiology. Childhood cat ownership has been hypothesised as an intermediary marker of T. Gondii infection and, by proxy, as a risk factor for later psychosis. Evidence supporting this hypothesis is, however, limited. Method We used birth cohort data from the Avon Longitudinal Study of Parents and Children (ALSPAC) to investigate whether cat ownership in pregnancy and childhood (4, 10 years old) was associated with psychotic experiences (PEs) in early (age 13; N=6,705) and late (age 18; N=4,676) adolescence, rated from semi-structured interviews. We used logistic regression to examine associations between cat ownership and PEs, adjusting for several sociodemographic and socioeconomic factors, household characteristics and dog ownership. Missing data were handled via multiple imputation. Results Cat ownership during pregnancy was not associated with PEs at age 13 (adjusted odds ratio [OR]: 1.15, 95% confidence interval [CI]: 0.97-1.35) or 18 years (OR: 1.08, 95%CI: 0.86-1.35). Initial univariable evidence that cat ownership at 4 and 10 years was associated with PEs at age 13 years did not persist after multivariable adjustment (4 years OR: 1.18, 95%CI: 0.94-1.48; 10 years OR 1.12, 95%CI: 0.92; 1.36). There was no evidence that childhood cat ownership was associated with PEs at 18 years old. Conclusions While pregnant women should continue to avoid handling soiled cat litter, given possible T Gondii exposure, our study strongly indicates that cat ownership in pregnancy or early childhood does not confer an increased risk of later adolescent PEs. PMID:28222824

  14. Core drilling of drillholes ONK-KR13, ONK-KR14 and ONK-KR15 in ONKALO at Olkiluoto 2010 - 2011

    International Nuclear Information System (INIS)

    Toropainen, V.

    2011-08-01

    As a part of the confirming site investigations at Olkiluoto, Suomen Malmi Oy (Smoy) core drilled three drillholes ONK-KR13 (120.45 m), ONK-KR14 (75.27 m) and ONK-KR15 (79.96 m) in ONKALO, at Olkiluoto in June 2010 - March 2011. The diameter of the drillholes is 75.7 mm. Sodium fluorescein was used as a label agent in the drilling water, and the drillholes were washed and flushed after the drilling. The deviations of the drillholes were measured with the deviation measuring instruments EMS and Gyro. The core samples were logged according to Posiva's normal procedure for drillholes. The main rock types are veined and diatexitic gneisses and pegmatitic granite. The average natural fracture frequencies and RQDs of the core samples are 1.6 pcs/m and 97.0 % (ONK-KR13), 0.5 pcs/m and 99.3 % (ONK-KR14) and 1.6 pcs/m and 97.3 % (ONK-KR15). In drillhole ONK-KR13 one, and in drillhole ONK-KR15 three fractured zones were intersected. There was no fractured zones in drillhole ONK-KR14. Rock mechanical tests were performed to core samples. The average uniaxial compressive strength was 143.2 MPa, the average Young's Modulus was 57.3 GPa and the average Poisson's ratio was 0.25. (orig.)

  15. The relationship of gross upper and lower limb motor competence to measures of health and fitness in adolescents aged 13–14 years

    Science.gov (United States)

    Liu, Francesca; Mahmoud, Wala; Metz, Renske; Beunder, Kyle; Delextrat, Anne; Morris, Martyn G; Esser, Patrick; Collett, Johnny; Meaney, Andy; Howells, Ken; Dawes, Helen

    2018-01-01

    Introduction Motor competence (MC) is an important factor in the development of health and fitness in adolescence. Aims This cross-sectional study aims to explore the distribution of MC across school students aged 13–14 years old and the extent of the relationship of MC to measures of health and fitness across genders. Methods A total of 718 participants were tested from three different schools in the UK, 311 girls and 407 boys (aged 13–14 years), pairwise deletion for correlation variables reduced this to 555 (245 girls, 310 boys). Assessments consisted of body mass index, aerobic capacity, anaerobic power, and upper limb and lower limb MC. The distribution of MC and the strength of the relationships between MC and health/fitness measures were explored. Results Girls performed lower for MC and health/fitness measures compared with boys. Both measures of MC showed a normal distribution and a significant linear relationship of MC to all health and fitness measures for boys, girls and combined genders. A stronger relationship was reported for upper limb MC and aerobic capacity when compared with lower limb MC and aerobic capacity in boys (t=−2.21, degrees of freedom=307, P=0.03, 95% CI −0.253 to –0.011). Conclusion Normally distributed measures of upper and lower limb MC are linearly related to health and fitness measures in adolescents in a UK sample. Trial registration number NCT02517333. PMID:29629179

  16. Dental anxiety among university students and its correlation with their field of study.

    Science.gov (United States)

    Al-Omari, Wael Mousa; Al-Omiri, Mahmoud Khalid

    2009-01-01

    This study was designed to investigate the subjective ratings of dental anxiety levels among university students enrolled at Jordan University of Science and Technology. In addition, the present study aimed to explore the sources of dental anxiety and the impact of gender on the perceived dental anxiety and the correlation between field of study and dental anxiety level. The Modified Corah Dental Anxiety Scale was used to measure dental anxiety among the study population. Six hundred subjects were recruited into the study from Jordanian undergraduate students from the faculties of Medicine, Engineering, and Dentistry. Five hundred and thirty five complete questionnaires were returned, which accounts for a response rate of 89.2%. The totals of the mean anxiety scores were the following: Medical students, 13.58%; Engineering students, 13.27% and dental students, 11.22%. About 32% of the study population has scored 15 or more. Dental students had the lowest percentage of those who scored 15 or more. Surprisingly, the medical students were responsible for the highest percentage of those who scored 15 or above. Although women demonstrated statistically higher total dental anxiety scores than men (p= 0.03), the difference between both genders was small and could be clinically insignificant. The students were anxious mostly about tooth drilling and local anesthetic injection. Lack of adequate dental health education may result in a high level of dental anxiety among non-dental university students in Jordan. Further studies are required to identify the correlates of dental anxiety among university students.

  17. Effects of arbuscular mycorrhizal fungi on gas exchange and stable isotope ratio of δ13C, δ15N of leymus chinensis plant

    International Nuclear Information System (INIS)

    Shi Weiqi; Wang Guoan; Li Xiaolin

    2008-01-01

    Leymus chinensis, one of dominant species in Inner Mongolia grassland, was selected to evaluate the effects of arbuscular mycorrhizal fungi (AMF) on plant gas change parameters and stable isotope ratio in pot culture. The plant was inoculated with two mycorrhizal fungi, Glomus intraradices and Glomus claroidum, and the uninoculated plant was used as the control check. On the 45th , 60th , 75th days after sowing, gas exchange parameters and stable isotope ratio were measured. The results showed that AM infection promoted phosphoms content, stomatal conductance and photosynthetic rate of Leymus chinensis, reduced host δ 15 N, however, it did not influence host intrinsic water using efficiency and δ 13 C. It was the growth time that significantly affected the gas exchange and stable isotope ratio of δ 13 C and δ 15 N. And the interaction of inoculation and growth time also influenced on the net photosynthetic rate, δ 13 C and δ 15 N of the host. Stomatal conductance and photosynthetic rate were always changed the same direction by arbuscular mycorrhizal fungi causing no significant difference between mycorrhizal and non-mycorrhizal plant. AMF absorbed nitrogen and accumulated δ 15 N, thus, it transformed less 15 N into the host, and as a result, the mycorrhizal plant had lower δ 15 N. Therefore, the results gave a new way and reference to know of the grass balance of carbon gain and water cost and the nitrogen cycle in grassland. (authors)

  18. [Secular trends of height among Chinese students aged 17 in 18 ethnic minorities from 1985 to 2010].

    Science.gov (United States)

    Song, Yi; Hu, Pei-jin; Zhang, Bing; Ma, Jun

    2015-06-18

    To analyze the secular trends of height among Chinese students aged 17 in different ethnic minorities from 1985 to 2010. A total of 18 Chinese ethnic minorities' students, including Mongolian, Hui, Uygur, Zhuang, Korean, Tibetan, Miao, Buyi, Dong, Bai, Tujia, Hani, Dai, Lisu, Wa, Nakhi, Tu and Qiang as subjects were sampled from the 1985, 1995, 2000, 2005 and 2010 Chinese National Surveys on Students' Constitution and Health. The heights of 17 years old people by gender in various ethnic minorities were analyzed and compared. From 1985 to 2010, the increments of adult heights increased significantly in many ethnic minorities' boys. In 2010, the average height of boys aged 17 years in each minority group was higher than 162 cm and was higher than 170 cm among boys from Hui, Mongolian and Korean groups. The ethnics with height growth rates of more than 2 cm per decade in boys were Hui (2.64 cm/decade) and Dong (2.05 cm/decade) and the ethnics with height growth rates of more than 1 cm per decade were Korean (1.99 cm/decade), Tibetan (1.90 cm/decade), Hani (1.80 cm/decade) and the other 9 minority groups. The average height of girls aged 17 years in each minority group was higher than 150 cm in 2010. The heights showed an upward trend in 15 minority groups, but with different degrees. The ethnics with height growth rates of more than 1 cm per decade were Hui (1.56 cm/decade) and Korean (1.29 cm/decade). The increments that were significant between 1985 and 2010 were Hui (3.89 cm), Korean (3.23 cm), Dong (2.35 cm) and the other 6 minority groups (Pminority groups during the past 25 years, but there was an obvious disequilibrium among various ethnic minorities. We should pay more attention to the minority groups with poor growth and give them more help. Meanwhile, we should also pay attention to the negative effects of the secular growth trend on those minority groups with fast increasing adult height.

  19. Problematic internet use among high school students: Prevalence, associated factors and gender differences.

    Science.gov (United States)

    Vigna-Taglianti, Federica; Brambilla, Romeo; Priotto, Bruna; Angelino, Remo; Cuomo, GianLuca; Diecidue, Roberto

    2017-11-01

    This study aimed to measure the prevalence of Problematic Internet Use (PIU) among high school students and to identify factors associated with PIU underlining gender differences. The students filled a self-administered, anonymous questionnaire collecting information on demographic characteristics and patterns of Internet use. Multiple logistic regression analysis was performed to identify factors associated with PIU in the overall sample and by gender. Twenty-five schools and 2022 students participated in the survey. Prevalence of PIU was 14.2% among males and 10.1% among females. Males 15-year-olds and females 14-year-olds had the highest PIU prevalence that progressively lowered with age among females. Only 13.5% of pupils declared parents controlled their Internet use. The sensation of feeling lonely, the frequency of use, the number of hours of connection, and visiting pornographic websites were associated with the risk of PIU in both genders. Attending vocational schools, the activities of chatting and file downloading, and the location of use at Internet point among males, and younger age among females were associated with PIU, whilst information searching was protective among females. PIU could become a public health problem in the next years. The physical and mental health consequences should be studied. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Summer Students

    CERN Multimedia

    2005-01-01

    SUMMER STUDENT LECTURE PROGRAMME Main Auditorium, bldg. 500 DATE TIME LECTURER TITLE Monday 25 July 09:15 - 11:00 A. PICH The Standard Model (2-3/8) 11:15 - 12:00 J. STACHEL Quark Gluon Plasma Physics (1/3) 12:00 Discussion Session Tuesday 26 July 09:15 - 10:00 A. PICH The Standard Model (4/8) 10:15 - 12:00 J. STACHEL Quark Gluon Plasma Physics (2-3/3) 12:00 Discussion Session Wednesday 27 July 09:15 - 11:00 A. PICH The Standard Model (5-6/8) 11:15 - 12:00 J-P. DELAHAYE The CLIC Concept and Technology for an e+e-Collider at the Energy Frontier 11:15 - 12:00 Discussion Session Thursday 28 July 09:15 - 10:00 A. PICH The Standard Model (7/8) 10:15 - 11:00 P. SPHICAS Data Acquisition Systems (1/2) 11:15 - 12:00 R. JACOBSEN From Raw data to Physics Results (1/2) 12:00 Discussion Session Friday 29 July 09:15 - 10:00 A. PICH The Standard Model (8/8) 10:15 - 11:00 P. SPHICAS Data Acquisition Systems (2/2) 11:15 - 12:00 R. JACOBSEN Fr...

  1. Attitudes of Veterinary Teaching Staff and Exposure of Veterinary Students to Early-Age Desexing, with Review of Current Early-Age Desexing Literature.

    Science.gov (United States)

    Jupe, Alannah; Rand, Jacquie; Morton, John; Fleming, Sophie

    2017-12-25

    Approximately 50% of cats admitted to Australian shelters are kittens, and 26% of dogs are puppies, and, particularly for cats, euthanasia rates are often high. Cats can be pregnant by 4 months of age, yet the traditional desexing age is 5-6 months, and studies in Australasia and Nth America reveal that only a minority of veterinarians routinely perform early age desexing (EAD) of cats or dogs, suggesting they are not graduating with these skills. This study aimed to describe the attitudes of veterinary teaching staff in Australian and New Zealand universities towards EAD, and to determine if these changed from 2008 to 2015. It also aimed to identify students' practical exposure to EAD. Most (64%) of the 25 participants in 2015 did not advocate EAD in their teaching and, in their personal opinion, only 32% advocated it for cats. Concerns related to EAD cited by staff included anesthetic risk, orthopedic problems, hypoglycemia, and, in female dogs, urinary incontinence. Those who advocated EAD cited benefits of population control, ease of surgery and behavioral benefits. Only three of the eight universities provided a majority of students with an opportunity to gain exposure to EAD procedures before graduation, and in two of these, most students had an opportunity to perform EAD. In conclusion, most veterinary students in Australia and New Zealand are not graduating with the knowledge or skills to perform EAD, and have little opportunity while at university to gain practical exposure. Welfare agencies could partner with universities to enable students to experience EAD.

  2. Maternally derived microduplications at 15q11-q13: implication of imprinted genes in psychotic illness

    NARCIS (Netherlands)

    Ingason, A.; Kirov, G.; Giegling, I.; Hansen, T.; Isles, A.R.; Jakobsen, K.D.; Kristinsson, K.T.; Roux, L. le; Gustafsson, O.; Craddock, N.; Moller, H.J.; McQuillin, A.; Muglia, P.; Cichon, S.; Rietschel, M.; Ophoff, R.A.; Djurovic, S.; Andreassen, O.A.; Pietilainen, O.P.H.; Peltonen, L.; Dempster, E.; Collier, D.A.; St Clair, D.; Rasmussen, H.B.; Glenthoj, B.Y.; Kiemeney, L.A.L.M.; Franke, B.; Tosato, S.; Bonetto, C.; Saemundsen, E.; Hreidarsson, S.J.; Nothen, Markus; Gurling, H.; O'Donovan, M.C.; Owen, M.J.; Sigurdsson, E.; Petursson, H.; Stefansson, H.; Rujescu, D.; Stefansson, K.; Werge, T.

    2011-01-01

    OBJECTIVE: Rare copy number variants have been implicated in different neurodevelopmental disorders, with the same copy number variants often increasing risk of more than one of these phenotypes. In a discovery sample of 22 schizophrenia patients with an early onset of illness (10-15 years of age),

  3. MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13

    OpenAIRE

    Sankaran, Vijay G.; Menne, Tobias F.; Šćepanović, Danilo; Vergilio, Jo-Anne; Ji, Peng; Kim, Jinkuk; Thiru, Prathapan; Orkin, Stuart H.; Lander, Eric S.; Lodish, Harvey F.

    2011-01-01

    Many human aneuploidy syndromes have unique phenotypic consequences, but in most instances it is unclear whether these phenotypes are attributable to alterations in the dosage of specific genes. In human trisomy 13, there is delayed switching and persistence of fetal hemoglobin (HbF) and elevation of embryonic hemoglobin in newborns. Using partial trisomy cases, we mapped this trait to chromosomal band 13q14; by examining the genes in this region, two microRNAs, miR-15a and -16-1, appear as t...

  4. Confidentiality Concerns and Sexual and Reproductive Health Care Among Adolescents and Young Adults Aged 15-25.

    Science.gov (United States)

    Copen, Casey E; Dittus, Patricia J; Leichliter, Jami S

    2016-12-01

    Data from the National Survey of Family Growth •About 7% of persons aged 15-25 would not seek sexual or reproductive health care because of concerns that their parents might find out about it. •For females aged 15-17 and 18-25, those who had confidentiality concerns were less likely to receive sexual and reproductive health services in the past year compared with those without these concerns. •Less than one-half of teenagers aged 15-17 (38.1%) spent some time alone in the past year during a visit with a doctor or other health care provider without a parent, relative, or guardian in the room. •Teenagers aged 15-17 who spent some time alone during a visit with a health care provider were more likely to have received sexual or reproductive health services in the past year compared with those who had not. Confidentiality concerns can impact adolescent and young adults' access to sexual and reproductive health services (1-4). Young people who are covered by their parents' private health insurance may be deterred from obtaining these services due to concerns that their parents might find out about it (2). Similarly, confidentiality concerns may arise because youth seeking such services may not have time alone during a visit with a health care provider (4). This report describes two measures related to confidentiality concerns and sexual and reproductive health care. All material appearing in this report is in the public domain and may be reproduced or copied without permission; citation as to source, however, is appreciated.

  5. Age peculiarities of the structure of senior pupils' and students' initiativity

    Directory of Open Access Journals (Sweden)

    V V Alekseyeva

    2009-03-01

    Full Text Available The results of this research of age peculiarities of senior pupils' and students' initiativity based on multimeasureble-functional model of personal structure of their qualities, which gives an opportunity to study, the display of individual peculiarities of initiativity are considered in this article.

  6. The relative isotopic abundance (δ13C, δ15N) during composting of agricultural wastes in relation to compost quality and feedstock.

    Science.gov (United States)

    Inácio, Caio T; Magalhães, Alberto M T; Souza, Paulo O; Chalk, Phillip M; Urquiaga, Segundo

    2018-05-01

    Variations in the relative isotopic abundance of C and N (δ 13 C and δ 15 N) were measured during the composting of different agricultural wastes using bench-scale bioreactors. Different mixtures of agricultural wastes (horse bedding manure + legume residues; dairy manure + jatropha mill cake; dairy manure + sugarcane residues; dairy manure alone) were used for aerobic-thermophilic composting. No significant differences were found between the δ 13 C values of the feedstock and the final compost, except for dairy manure + sugarcane residues (from initial ratio of -13.6 ± 0.2 ‰ to final ratio of -14.4 ± 0.2 ‰). δ 15 N values increased significantly in composts of horse bedding manure + legumes residues (from initial ratio of +5.9 ± 0.1 ‰ to final ratio of +8.2 ± 0.5 ‰) and dairy manure + jatropha mill cake (from initial ratio of +9.5 ± 0.2 ‰ to final ratio of +12.8 ± 0.7 ‰) and was related to the total N loss (mass balance). δ 13 C can be used to differentiate composts from different feedstock (e.g. C 3 or C 4 sources). The quantitative relationship between N loss and δ 15 N variation should be determined.

  7. Dental attendance, perceptions of cost and self-care of school year 12 and 13 students: A focus on Southland, New Zealand.

    Science.gov (United States)

    Murray, Colleen; Densie, Ian Kenneth; Morgan, Christian

    2015-12-01

    Adolescents and emerging adults can provide dentists with many challenges. Little information is available on their perceptions of dental costs once they turn 18 and dentistry is no longer State-funded. The aim of this study was to explore the use of dental care by Southland students in years 12 and 13, their perceptions of the cost of four common dental procedures, self-related oral health and dental self-care habits, time off school related to dental problems, and knowledge and views regarding fluoride. After ethical approval, a 26-question survey was conducted of all Southland students in years 12 and 13. Data were statistically analysed in SPSS version 20 with the alpha value set at 0.05. The participation rate was 49.6%. Regular attendance for examinations was reported by 77.5% with non-attendance mainly related to attitudes around lack of importance or necessity. Reported dental attendance varied according to gender, ethnicity and decile rating of school attended. Although some were accurate in their estimations of dental costs, the standard deviation for all procedures was large. The majority thought that costs put people off going to the dentist. While 74.8% brushed their teeth at least twice daily, only 26.6% flossed regularly. Knowledge regarding fluoride was lacking. It may be advantageous to include education regarding costs of dental care with patients of this age. This may motivate them to improve their self-care and ensure that their oral health is of a high standard before their dental needs are no longer State-funded.

  8. Udviklingen i energisk fysisk aktivitet og fysisk inaktivitet blandt 11-15-årige 1988-2002

    DEFF Research Database (Denmark)

    Holstein, Bjørn E; Henriksen, Pia Elena; Krølner, Rikke

    2007-01-01

    INTRODUCTION: The increasing prevalence of overweight and obesity among children and adolescents suggests a need to study the development in main predictors of obesity, like eating habits and physical activity. The objective was to describe self-reported vigorous physical activity versus physical...... inactivity among children and adolescents over a period of 14 years, 1988-2002. MATERIAL AND METHODS: The study population was the Health Behaviour in School-aged Children (HBSC) study among nationally representative samples of 11, 13 and 15 year old students in 1988, 1991, 1994, 1998, and 2002. The data...... of children and adolescents do not comply with the national recommendations that children should be physically active at least 60 minutes per day. The physical activity level decreased from 1988 to 2002. There is a need for extraordinary efforts to increase physical activity among children and adolescents...

  9. ENGAGEMENT AND BURNOUT AMONG NURSING AND PSYCHOLOGY STUDENTS IN SLOVAKIA

    OpenAIRE

    Zuzana Škodová; Ľubica Bánovčinová; Petra Lajčiaková

    2017-01-01

    Aim: The aim of the study was to examine the differences in engagement and burnout syndrome in students of nursing/midwifery and psychology in Slovakia. Design: A cross-sectional design was used. Methods: 171 university students on a baccalaureate program participated in the research (90.9% females; age 20.6 ± 1.3; 80 psychology students, 91 nursing/midwifery students). The School Burnout Inventory (SBI) and Utrecht Work Engagement Scale (UWES) were employed as measurement methods. Results: A...

  10. Longitudinal retention of anatomical knowledge in second-year medical students.

    Science.gov (United States)

    Doomernik, Denise E; van Goor, Harry; Kooloos, Jan G M; Ten Broek, Richard P

    2017-06-01

    The Radboud University Medical Center has a problem-based, learner-oriented, horizontally, and vertically integrated medical curriculum. Anatomists and clinicians have noticed students' decreasing anatomical knowledge and the disability to apply knowledge in diagnostic reasoning and problem solving. In a longitudinal cohort, the retention of anatomical knowledge gained during the first year of medical school among second-year medical students was assessed. In May 2011, 346 medical students applied for the second-year gastro-intestinal (GI) tract course. The students were asked to participate in a reexamination of a selection of anatomical questions of an examination from October 2009. The examination consisted of a clinical anatomy case scenario and two computed tomography (CT) images of thorax and abdomen in an extended matching format. A total of 165 students were included for analysis. In 2011, students scored significantly lower for the anatomy examination compared to 2009 with a decline in overall examination score of 14.7% (±11.7%). Decrease in knowledge was higher in the radiological questions, compared to the clinical anatomy cases 17.5% (±13.6%) vs. 7.9% (±10.0%), respectively, d = 5.17. In both years, male students scored slightly better compared to female students, and decline of knowledge seems somewhat lower in male students (13.1% (±11.1%) vs. 15.5% (±12.0%), respectively), d = -0.21. Anatomical knowledge in the problem-oriented horizontal and vertical integrated medical curriculum, declined by approximately 15% 1.5 year after the initial anatomy course. The loss of knowledge in the present study is relative small compared to previous studies. Anat Sci Educ 10: 242-248. © 2016 American Association of Anatomists. © 2016 American Association of Anatomists.

  11. Adolescent Suicide Rates Between 1990 and 2009: Analysis of Age Group 15-19 Years Worldwide.

    Science.gov (United States)

    Kõlves, Kairi; De Leo, Diego

    2016-01-01

    The aim of the current analysis is to analyze suicide rates in adolescents aged 15-19 years in decades between 1990 and 2009 worldwide. Suicide data were obtained from the World Health Organization Mortality Database and population data from the World Bank Data set. In total, 81 countries or territories, having data at least for 5 years in 1990-1999 and in 2000-2009, were included in the analysis. Additional analysis for regional trends with 57 countries was performed. Over the decades considered, analysis showed a declining trend in the overall suicide rate for males from 10.30 to 9.51 per 100,000 (p = .076), and for females from 4.39 to 4.18 (p = .472). The average suicide rate showed a significant decline for both genders in Europe, dropping from 13.13 to 10.93 (p = .001) in males and from 3.88 to 3.34 in females (p = .038). There was a significant increase in South American countries for males, from 7.36 to 11.47 (p = .016), and a close to significant rise for females, from 5.59 to 7.98 (p = .053). Although other world regions did not show significant trends, there were several significant changes at country level. Reasons behind the decrease in Western countries could potentially be related to the overall improvements in global health; the possible contribution of suicide prevention activities remains unclear. Increases in several South American countries might be related to economic recession and its impact on adolescents from diverse cultural backgrounds, and partly also to improvements in mortality registration. Copyright © 2016 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  12. The Relationship of Korean Students' Age and Years of English-as-a-Foreign-Language Exposure with English-Reading Ability: A Cross-Age Study

    Science.gov (United States)

    Fitzgerald, Jill; Stenner, A. Jackson; Sanford-Moore, Eleanor E.; Koons, Heather; Bowen, Kimberly; Kim, Kee Hyung

    2015-01-01

    The purpose of the present cross-age study with South Korean students was to investigate the relationship of age and years of English-as-a-foreign-language (EFL) exposure with English-reading ability. The main research question was, "Do individuals' age and number of years of English exposure interact in relation to English-reading…

  13. Exploring Language Awareness through Students' Engagement in Language Play

    Science.gov (United States)

    Ahn, So-Yeon

    2016-01-01

    The present study explores Korean students' demonstration of language awareness through their engagement in language play. Grounded in the understanding of the relationship between language play and an "engagement with language" (EWL) perspective, this ethnographic and discourse analytic study investigates how Korean students aged 11-15

  14. Isotopic signatures (13C/12C; 15N/14N) of blue penguin burrow soil invertebrates : carbon sources and trophic relationships

    International Nuclear Information System (INIS)

    Hawke, D.J.; Clark, J.M.

    2010-01-01

    Seabird burrows provide a soil environment for processing discards such as feathers and guano, hence constituting a primary interface between the sea and the land. This study involved collection and culturing of soil invertebrates from three blue penguin (Eudyptula minor) burrows, and examined their 13 C/ 12 C and 15 N/ 14 N isotopic composition in relation to potential burrow resources (terrestrial plant litter, burrow soil, guano, blue penguin feathers). Two taxa (cerylonid beetles and small tineid moth larvae) had a depleted 13 C/ 12 C indicative of a level of dependence on C from terrestrial soil. Tineid moth larvae (Monopis crocicapitella and (or) M. ethelella) substantially increased their 13 C/ 12 C enrichment during development, implying increasing dependence on marine C. Remaining taxa, both decomposers and predators, had 13 C/ 12 C intermediate between guano and feathers. Larval and emergent fleas had the most enriched 13 C/ 12 C , indicative of a greater dependence on feather C and the likelihood of co-processing with guano. Pseudoscorpions and histerid beetles had overlapping isotopic enrichments implying competition for prey, but were spatially separated in burrow soil. With their highly enriched 15 N/ 14 N and marine 13 C/ 12 C, larvae and protonymphs of the histiostomatid mite Myianoetus antipodus stood alone. Blue penguin burrows therefore support a diverse invertebrate fauna that incorporates terrestrial soil as well as varying proportions of the various blue penguin discards. (author). 45 refs., 1 fig., 1 tab.

  15. Junior High School Students' Ideas about the Shape and Size of the Atom

    Science.gov (United States)

    Cokelez, Aytekin

    2012-01-01

    The concept of the atom is one of the building blocks of science education. Although the concept is a foundation for students' subsequent learning experiences, it is difficult for students to comprehend because of common misconceptions and its abstractness. The purpose of this study is to examine junior high school students' (ages 12-13) ideas…

  16. Relational Aggression in Preschool Students: An Exploration of the Variables of Sex, Age, and Siblings

    Directory of Open Access Journals (Sweden)

    Karen A. Morine

    2011-01-01

    Full Text Available In this study, researchers wished to ascertain whether there were age (three- and four-year old, sibling (with or without older siblings, and sex (male and female differences in the use of relational aggression in preschool students as rated by peers and teachers. In order to answer this research question, two 2 × 2 × 2 factorial ANOVA procedures with the relational aggression composite score as the dependent variable on the PSBS-P and PSBS-T were used for peer and teacher assessment, respectively, of relational aggression. Results revealed that in the peer ratings of preschool students' relationally aggressive behavior, there was an disordinal age by sibling interaction, in which four-year-old children with siblings were significantly more likely to be rated by their peers as using relational aggression than three-year-old children without siblings. In the teacher ratings of preschool students' relationally aggressive behavior, a main effect for age was observed. Teachers rated four-year old children as evidencing significantly higher levels of relational aggression as compared to three-year-olds. No sex differences were observed in the use of relational aggression either at age three or age four in this sample. Implications for these findings are presented.

  17. THE RELATIONSHIP BETWEEN MOTOR COMPETENCE AND PHYSICAL FITNESS IS WEAKER IN THE 15-16 YR. ADOLESCENT AGE GROUP THAN IN YOUNGER AGE GROUPS (4-5 YR. AND 11-12 YR.).

    Science.gov (United States)

    Haga, Monika; Gísladóttír, Thórdís; Sigmundsson, Hermundur

    2015-12-01

    Developing motor competence and physical fitness can affect the maintenance of a sufficient level of physical activity in children and adolescents. This study assesses the relationship between motor competence and physical fitness from childhood through early adolescence. A cross-sectional sample of 194 participants from 4 to 16 years old were divided into three groups; 4-6 yr. (n=42, M age=5.2, SD 0.6), 11-12 yr. (n=58, M age=12.4, SD=0.3), and 15-16 yr. (n=94, M age=15.9, SD=0.4). To assess motor competence, each child completed the Movement Assessment Battery for Children (MABC). To measure physical fitness, three tasks (strength, speed, and endurance) were selected from the Test of Physical Fitness (TPF). To analyze the significance of the difference between the correlation coefficient in the three age groups (samples) (4-6, 11-12, and 15-16 yr.), Fischer r-to-z transformation was used. The correlation (Pearson's) between motor competence and physical fitness in the age groups was statistically higher for the youngest age groups (4-6 and 11-12 yr.) and the adolescent group (age 15-16). The differences between the two youngest age groups were not statistically significant. The results demonstrate that the correlation between motor competence and physical fitness decreases with age.

  18. Use of Facebook: A Case Study of Singapore Students' Experience

    Science.gov (United States)

    Hew, Khe Foon; Cheung, Wing Sum

    2012-01-01

    Facebook has become one of the most popular social network sites among many students. However, current research on Facebook use has focused mainly on Anglo-American students. Relatively little is known about Facebook use in Singapore. Data were collected from 83 students (ages ranged from 15 to 23). This study uses a naturalistic case study…

  19. Hydrology and water quality in 13 watersheds in Gwinnett County, Georgia, 2001–15

    Science.gov (United States)

    Aulenbach, Brent T.; Joiner, John K.; Painter, Jaime A.

    2017-02-23

    The U.S. Geological Survey (USGS), in cooperation with Gwinnett County Department of Water Resources, established a Long-Term Trend Monitoring (LTTM) program in 1996. The LTTM program is a comprehensive, long-term, water-quantity and water-quality monitoring program designed to document and analyze the hydrologic and water-quality conditions of selected watersheds in Gwinnett County, Georgia. Water-quality monitoring initially began in six watersheds and currently [2016] includes 13 watersheds.As part of the LTTM program, streamflow, precipitation, water temperature, specific conductance, and turbidity were measured every 15 minutes for water years 2001–15 at 12 of the 13 watershed monitoring stations and for water years 2010–15 at the other watershed. In addition, discrete water-quality samples were collected seasonally from May through October (summer) and November through April (winter), including one base-flow and three stormflow event composite samples, during the study period. Samples were analyzed for nutrients (nitrogen and phosphorus), total organic carbon, trace elements (total lead and total zinc), total dissolved solids, and total suspended sediment (total suspended solids and suspended-sediment concentrations). The sampling scheme was designed to identify variations in water quality both hydrologically and seasonally.The 13 watersheds were characterized for basin slope, population density, land use for 2012, and the percentage of impervious area from 2000 to 2014. Several droughts occurred during the study period—water years 2002, 2007–08, and 2011–12. Watersheds with the highest percentage of impervious areas had the highest runoff ratios, which is the portion of precipitation that occurs as runoff. Watershed base-flow indexes, the ratio of base-flow runoff to total runoff, were inversely correlated with watershed impervious area.Flood-frequency estimates were computed for 13 streamgages in the study area that have 10 or more years of annual

  20. Selective detection of carbon-13, nitrogen-15, and deuterium labeled metabolites by capillary gas chromatography-chemical reaction interface/mass spectrometry

    International Nuclear Information System (INIS)

    Chace, D.H.; Abramson, F.P.

    1989-01-01

    We have applied a new chemical reaction interface/mass spectrometer technique (CRIMS) to the selective detection of 13C-, 15N-, and 2H-labeled phenytoin and its metabolites in urine following separation by capillary gas chromatography. The microwave-powered chemical reaction interface converts materials from their original forms into small molecules whose mass spectra serve to identify and quantify the nuclides that make up each analyte. The presence of each element is followed by monitoring the isotopic variants of CO2, NO, or H2 that are produced by the chemical reaction interface. Chromatograms showing only enriched 13C and 15N were produced by subtracting the abundance of naturally occurring isotopes from the observed M + 1 signal. A selective chromatogram of 2H (D) was obtained by measuring HD at m/z 3.0219 with a resolution of 2000. Metabolites representing less than 1.5% of the total labeled compounds could be identified in the chromatogram. Detection limits from urine of 380 pg/mL of a 15N-labeled metabolite, 7 ng/mL of a 13C-labeled metabolite, and 16 ng/mL of a deuterium labeled metabolite were determined at a signal to noise ratio of 2. Depending on the isotope examined, a linear dynamic range of 250-1000 was observed using CRIMS. To identify many of these labeled peaks (metabolites), the chromatographic analysis was repeated with the chemical reaction interface turned off and mass spectra obtained at the retention times found in the CRIMS experiment. CRIMS is a new analytical method that appears to be particularly useful for metabolism studies

  1. Construction of a DNA library representing 15q11-13 by subtraction of two flow sorted marker chromosome-specific libraries

    Energy Technology Data Exchange (ETDEWEB)

    Blennow, E.; Werelius, B.; Nordenskjoeld, M. [Karolinska Hospital, Stockholm (Sweden)] [and others

    1994-09-01

    Constitutional extra {open_quotes}marker chromosomes{close_quotes} are found in {approx}0.5/1000 of newborns. Of these, 50% are inverted duplications of the pericentromeric region of chromosome 15, including two variants; (1) inv dup(15)(pter{yields}q11:q11{yields}pter) and (2) inv dup(15) (pter{yields}q12-13::q12-13{yields}pter). Variant (1) is found in phenotypically normal individuals, whereas variant (2) will produce a typical clinical picture including mental retardation, autism, hyperactivity and discrete dysmorphic features. Fluorescence in situ hybridization (FISH) using single copy probes from the Prader-Willi region confirms these observations as well as chromosome painting using a flow-sorted marker chromosome-specific library from a variant (1) marker, hybridized to the chromosomes of a patient with a variant (2) marker chromosome. Followingly, a flow-sorted biotinylated variant (1) library was subtracted from a non-labeled variant (2) library using magnetic beads and subsequent amplification by degenerate oligonucleotide-primed PCR (DOP-PCR). The successful result was demonstrated by using the amplified material for chromosome painting on chromosome slides from variant (1) and variant (2) patients. We have constructed a library from 15q11-13. This region contains genes producing a specific abnormal phenotype when found in a tri- or tetrasomic state. The region also contains the genes responsible for the Prader-Willi and Angelman syndromes when the paternal/maternal copy is missing, respectively. It is therefore a region where parental imprinting plays an important role. The isolated library may be used to isolate single copy clones which will allow further investigations of this region.

  2. Investigating of Memory - Colours of Intellectually Disabled Children and Virtual Game Addict Students

    Science.gov (United States)

    Sik Lányi, Cecília

    We describe an investigation of memory colours. For this investigation Flash test software was developed. 75 observers used this test software in 4 groups: average elementary school children (aged: 8-9 years), intellectually disabled children (age: 9-15), virtual game addict university students (average age: 20) and university students who play with VR games rarely or never (average age: 20). In this pilot test we investigated the difference of memory colours of these 4 groups.

  3. The Predictive Role of Teaching Styles on Omani Students' Mathematics Motivation

    Science.gov (United States)

    Aldhafri, Said; Alrajhi, Marwa

    2014-01-01

    The current study explored the effects of two teaching styles, authoritative and authoritarian, on students' mathematics motivation. The two motivational constructs examined were intrinsic and extrinsic motivation. Data were collected from 425 Omani 8th grade students (males = 202/females = 223, mean age = 13.44, SD = 0.79). Through two…

  4. Influence of Age, Sex, and Race on College Students' Exercise Motivation of Physical Activity

    Science.gov (United States)

    Egli, Trevor; Bland, Helen W.; Melton, Bridget F.; Czech, Daniel R.

    2011-01-01

    Objective: The authors examined differences in exercise motivation between age, sex, and race for college students. Participants: Students from 156 sections of physical activity classes at a midsize university were recruited (n = 2,199; 1,081 men, 1,118 women) in 2005-2006 and volunteered to complete the Exercise Motivation Inventory. Methods:…

  5. Health promoting interactive technology: Finnish, Norwegian, Russian and Swedish students' reflections.

    Science.gov (United States)

    Kostenius, Catrine; Hertting, Krister

    2016-09-01

    The aim of this study was to elucidate Finnish, Norwegian, Russian and Swedish students' reflections and ideas on how interactive technology can be used to promote health in school. The data were collected in the northern part of these four countries, and 630 students aged 13-15 filled out the World Health Organization's 'Health Behavior in School-Aged Children' self-completion questionnaire with one additional open question, which is analyzed in this article (n = 419). The phenomenological analysis resulted in four themes: A sense of control, Balancing enjoyable options, Sharing with others and Learning made easier. The students point out that interactive technology promotes empowerment and independence, reduces stress and makes learning easier. They argue for a healthy balance of Internet use for it to be health promoting. According to the students, good relationships increase well-being; and interactive technology can offer a way to socialize, provide a tool for meeting and making new friends, help when not feeling well and give support when encouraging classmates. We argue, based on the findings of the present study and previous research, that students need a combination of freedom and meaningful relationships with adults who have an empowered child perspective, to fully take advantage of the empowering effects of interactive technology. We suggest, as implications for practice, that teachers, school leaders and health care professionals find ways to act as partners using an appreciative process, asking questions on what works well, to make interactive technology an enabling technology to increase health literacy, thus improving health and well-being in students. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  6. Healthy Aging Actions to Advance the National Prevention Strategy: Healthy He