WorldWideScience

Sample records for spokane nl ii-2

  1. NL Kids online

    OpenAIRE

    Jos de Haan

    2010-01-01

    In Nederland, maar ook elders, verkennen jongeren intensief de mogelijkheden van internet. Deze verkenning begint overal op steeds jongere leeftijd. Jongeren krijgen te maken met zowel de positieve als de negatieve kanten van internet. Dit rapport bestudeert de aangeboden kansen en risico's van online activiteiten en komt met aanbevelingen hoe we positief gebruik kunnen stimuleren en de risico's beperken. NL Kids online is gebaseerd op de belangrijkste rapporten van het EU Kids online project...

  2. Spokane Tribal Hatchery, 2002 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Peone, Tim L. (Spokane Tribe of Indians, Willpinit, WA)

    2003-03-01

    The Spokane Tribal Hatchery (Galbraith Springs) project originated from the Northwest Power Planning Council (NPPC) 1987 Columbia Basin Fish and Wildlife Program. The goal of this project is to aid in the restoration and enhancement of the Lake Roosevelt and Banks Lake fisheries adversely affected by the construction and operation of Grand Coulee Dam. The objective is to produce kokanee salmon and rainbow trout for release into Lake Roosevelt for maintaining a viable fishery. The goal and objective of this project adheres to the NPPC Resident Fish Substitution Policy and specifically to the biological objectives addressed in the NPPC Columbia River Basin Fish and Wildlife Program to mitigate for hydropower related fish losses in the blocked area above Chief Joseph/Grand Coulee Dams.

  3. Spokane Tribal Hatchery, 2003 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Peone, Tim L. (Spokane Tribe of Indians, Wellpinit, WA)

    2004-05-01

    Due to the construction and operation of Grand Coulee Dam (1939), anadromous salmon have been eradicated and resident fish populations permanently altered in the upper Columbia River region. Federal and private hydropower dam operations throughout the Columbia River system severely limits indigenous fish populations in the upper Columbia. Artificial production has been determined appropriate for supporting a harvestable fishery for kokanee salmon (Oncorhynchus nerka) and rainbow trout (Oncorhynchus mykiss) in Lake Roosevelt and Banks Lake (Grand Coulee Dam impoundments). A collaborative multi-agency artificial production program for the Lake Roosevelt and Banks Lake fisheries exists consisting of the Spokane Tribal Hatchery, Sherman Creek Hatchery, Ford Trout Hatchery and the Lake Roosevelt Kokanee and Rainbow Trout Net Pen Rearing Projects. These projects operate complementary of one another to target an annual release of 1 million yearling kokanee and 500,000 yearling rainbow trout for Lake Roosevelt and 1.4 million kokanee fry/fingerlings for Banks Lake. Combined fish stocking by the hatcheries and net pen rearing projects in 2003 included: 899,168 kokanee yearlings released into Lake Roosevelt; 1,087,331 kokanee fry/fingerlings released into Banks Lake, 44,000 rainbow trout fingerlings and; 580,880 rainbow trout yearlings released into Lake Roosevelt. Stock composition of 2003 releases consisted of Lake Whatcom kokanee, 50:50 diploid-triploid Spokane Trout Hatchery (McCloud River) rainbow trout and Phalon Lake red-band rainbow trout. All kokanee were marked with either thermal, oxytetracyline or fin clips prior to release. Preliminary 2003 Lake Roosevelt fisheries investigations indicate hatchery/net pen stocking significantly contributed to harvestable rainbow trout and kokanee salmon fisheries. An increase in kokanee harvest was primarily owing to new release strategies. Walleye predation, early maturity and entrainment through Grand Coulee Dam continues to

  4. Spokane Tribal Hatchery, 2005 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Peone, Tim L. (Spokane Tribe of Indians, Wellpinit, WA)

    2006-03-01

    Due to the construction and operation of Grand Coulee Dam (1939), anadromous salmon have been eradicated and resident fish populations permanently altered in the upper Columbia River region. Federal and private hydropower dam operations throughout the Columbia River system severely limits indigenous fish populations in the upper Columbia. Artificial production has been determined appropriate for supporting harvestable fisheries for kokanee salmon (Oncorhynchus nerka) and rainbow trout (Oncorhynchus mykiss) in Lake Roosevelt and Banks Lake (Grand Coulee Dam impoundments). The Spokane Tribe, Washington Department of Fish and Wildlife, Colville Confederated Tribes and Lake Roosevelt Development Association/Lake Roosevelt Volunteer Net Pen Project are cooperating in a comprehensive artificial production program to produce kokanee salmon (Oncorhynchus nerka) and rainbow trout (Oncorhynchus mykiss) for annual releases into the project area. The program consists of the Spokane Tribal Hatchery, Sherman Creek Hatchery, Ford Trout Hatchery and Lake Roosevelt Rainbow Trout Net Pen Rearing Projects. The Lake Roosevelt and Banks Lake Fisheries Evaluation Program monitor and evaluates release strategies and production methods for the aforementioned projects. Between 1985 and 2005 the projects have collectively produced up to 800,000 rainbow trout and 4 million kokanee salmon for release into Lake Roosevelt and 1.4 million kokanee fry for Banks Lake annually. In 2005, the annual release goal included 3.3 million kokanee fry, 475,000 kokanee yearlings and 500,000 rainbow trout yearlings. Fish produced by this project in 2005 to meet collective fish production and release goals included: 3,446,438 kokanee fingerlings, 347,730 rainbow trout fingerlings and 525,721 kokanee yearlings. Kokanee yearlings were adipose fin clipped before release. Stock composition consisted of Meadow Creek and Lake Whatcom kokanee, diploid-triploid Spokane Trout Hatchery (McCloud River) rainbow trout and

  5. Spokane Tribal Hatchery, 2004 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Peone, Tim L. (Spokane Tribe of Indians, Wellpinit, WA)

    2005-03-01

    Due to the construction and operation of Grand Coulee Dam (1939), anadromous salmon have been eradicated and resident fish populations permanently altered in the upper Columbia River region. Federal and private hydropower dam operations throughout the Columbia River system severely limits indigenous fish populations in the upper Columbia. Artificial production has been determined appropriate for supporting a harvestable fishery for kokanee salmon (Oncorhynchus nerka) and rainbow trout (Oncorhynchus mykiss) in Lake Roosevelt and Banks Lake (Grand Coulee Dam impoundments). A collaborative multi-agency artificial production program for the Lake Roosevelt and Banks Lake fisheries exists consisting of the Spokane Tribal Hatchery, Sherman Creek Hatchery, Ford Trout Hatchery and the Lake Roosevelt Kokanee and Rainbow Trout Net Pen Rearing Projects. These projects operate complementary of one another to target an annual release of 1 million yearling kokanee and 500,000 yearling rainbow trout for Lake Roosevelt and 1.4 million kokanee fry/fingerlings for Banks Lake. Fish produced by this project in 2004 to meet collective fish production and release goals included: 1,655,722 kokanee fingerlings, 537,783 rainbow trout fingerlings and 507,660 kokanee yearlings. Kokanee yearlings were adipose fin clipped before release. Stock composition consisted of Lake Whatcom kokanee, 50:50 diploid-triploid Spokane Trout Hatchery (McCloud River) rainbow trout and Phalon Lake red-band rainbow trout. All kokanee were marked with either thermal, oxytetracyline or fin clips prior to release. Preliminary 2004 Lake Roosevelt fisheries investigations indicate hatchery/net pen stocking significantly contributed to harvestable rainbow trout and kokanee salmon fisheries. An increase in kokanee harvest was primarily owing to new release strategies. Walleye predation, early maturity and entrainment through Grand Coulee Dam continues to have a negative impact on adult kokanee returns and limits the

  6. The NAL-NL2 prescription procedure

    Directory of Open Access Journals (Sweden)

    G. Keidser

    2011-03-01

    Full Text Available NAL-NL2 is the second generation of prescription procedures from The National Acoustic Laboratories (NAL for fitting wide dynamic range compression (WDRC instruments. Like its predecessor NALNL1 (Dillon, 1999, NAL-NL2 aims at making speech intelligible and overall loudness comfortable. This aim is mainly driven by a belief that these factors are most important for hearing aid users, but is also driven by the fact that less information is available about how to adjust gain to optimise other parameters that affect prescription such as localisation, tonal quality, detection of environmental sounds, and naturalness. In both formulas, the objective is achieved by combining a speech intelligibility model and a loudness model in an adaptive computer- controlled optimisation process. Adjustments have further been made to the theoretical component of NAL-NL2 that are directed by empirical data collected during the past decade with NAL-NL1. In this paper, the data underlying NAL-NL2 and the derivation procedure are presented, and the main differences from NAL-NL1 are outlined.

  7. Behoeftepeiling onder de doelgroep van themapagina's Gezond Werk : Loketgezondleven.nl en Nisb.nl

    NARCIS (Netherlands)

    Wesselman M; van Dijk SA; CGL; vz

    2012-01-01

    Er is onderzoek uitgevoerd naar de informatiebehoefte van de doelgroep van twee websites rond Gezond Werk: Loketgezondleven.nl/settings/werk en Nisb.nl/werk. Het RIVM Centrum Gezond Leven (CGL) en het Nederlands Instituut voor Sport en Bewegen (NISB) voerden gezamenlijk dit onderzoek uit. Hiermee

  8. Ontwerprapport 2005 kiesBeter.nl

    NARCIS (Netherlands)

    Loon AJM van; PCAl Droomers; E Keesman; H Janssen; JAM Lijdsman; HB Mulder; Veen AA van der; Vrijsen WJJ; VTV

    2005-01-01

    Since September 2004 RIVM's Centre for Public Health Forecasting (VTV) in the Netherlands has been working on the development of an Internet portal for the general public called kiesBeter.nl ('Make a better choice'). Via this portal, consumers will have access to integrated information on health,

  9. Ground-Water Flow Model for the Spokane Valley-Rathdrum Prairie Aquifer, Spokane County, Washington, and Bonner and Kootenai Counties, Idaho

    Science.gov (United States)

    Hsieh, Paul A.; Barber, Michael E.; Contor, Bryce A.; Hossain, Md. Akram; Johnson, Gary S.; Jones, Joseph L.; Wylie, Allan H.

    2007-01-01

    This report presents a computer model of ground-water flow in the Spokane Valley-Rathdrum Prairie (SVRP) aquifer in Spokane County, Washington, and Bonner and Kootenai Counties, Idaho. The aquifer is the sole source of drinking water for more than 500,000 residents in the area. In response to the concerns about the impacts of increased ground-water withdrawals resulting from recent and projected urban growth, a comprehensive study was initiated by the Idaho Department of Water Resources, the Washington Department of Ecology, and the U.S. Geological Survey to improve the understanding of ground-water flow in the aquifer and of the interaction between ground water and surface water. The ground-water flow model presented in this report is one component of this comprehensive study. The primary purpose of the model is to serve as a tool for analyzing aquifer inflows and outflows, simulating the effects of future changes in ground-water withdrawals from the aquifer, and evaluating aquifer management strategies. The scale of the model and the level of detail are intended for analysis of aquifer-wide water-supply issues. The SVRP aquifer model was developed by the Modeling Team formed within the comprehensive study. The Modeling Team consisted of staff and personnel working under contract with the Idaho Department of Water Resources, personnel working under contract with the Washington Department of Ecology, and staff of the U.S. Geological Survey. To arrive at a final model that has the endorsement of all team members, decisions on modeling approach, methodology, assumptions, and interpretations were reached by consensus. The ground-water flow model MODFLOW-2000 was used to simulate ground-water flow in the SVPR aquifer. The finite-difference model grid consists of 172 rows, 256 columns, and 3 layers. Ground-water flow was simulated from September 1990 through September 2005 using 181 stress periods of 1 month each. The areal extent of the model encompasses an area of

  10. 76 FR 27668 - ASC Machine Tools, Inc., Spokane Valley, WA; Notice of Negative Determination on Reconsideration

    Science.gov (United States)

    2011-05-12

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-72,971] ASC Machine Tools, Inc... workers and former workers of ASC Machine Tools, Inc., Spokane Valley, Washington (the subject firm). The..., component parts of equipment, and spare parts. Workers are not separately identifiable by article produced...

  11. Sistemik Hipertansiyonlu Olgularda Santral Kornea Kalınl??? ve Retina Sinir Lifi Tabakası Kalınl???

    OpenAIRE

    ERG?N, Ahmet; ÇAKMAK, Yasin; GÜLLÜ, Reyhan

    2007-01-01

    Bu çalışma, sistemik hipertansiyonlu hastalarda santral kornea kalınl??? ve retina sinir lifi tabakası kalınl???nı ara?tırmak için planland?. Olguların santral kornea kalınlıkları (SKK) Pacline Optikon Ultrasonik pakimetre cihazı ile ölçüldü. Retina sinir lifi tabakası kalınl??? (RSLTK) ölçümü ise NFA II, GDx VCC cihazı ile yapıld?. Her olgu için üç ölçüm yapıld?, bunlardan en net olanı hesapland?. Sağlıklı bireyler ile sistemik hipertansiyonu olan hastalar arasında tüm ölçümler açıs?ndan ist...

  12. [What do you think of Thuisarts.nl? Experiences after 3 years of www.Thuisarts.nl].

    Science.gov (United States)

    Drenthen, Ton; Beijaert, Roy P H; Jansen, Patrick W M; Korevaar, Joke C; Smeele, Ivo J M

    2014-01-01

    Many people need information on health and disease, but the internet is a maze of medical information. In order to offer patients reliable medical information, and to support general practitioners, the Dutch College of General Practitioners (NHG) set up the public website Thuisarts.nl in 2011, which was later followed by an app. The NHG members survey amongst general practitioners from June 2013 showed that 90% of the general practitioners used Thuisarts.nl. The number of visitors was on average 60,000 a day. Information is also available from questionnaires filled in by the NIVEL Health Care Consumer Panel (n = 2846) and participants in a study on information technology and independence (n = 25). Thuisarts.nl meets an important need and is highly valued by doctors and patients. There are plans for the further development of Thuisarts.nl including short videos, illustrations, searchable anatomical structures and information from other reliable organisations such as associations of specialist doctors.

  13. Notification: EPA Region 10 Management Controls Over Allowing Substantial Public Funds to Construct the Spokane County Wastewater Treatment Facility

    Science.gov (United States)

    January 20, 2012. This EPA's OIG is initiating a review from an OIG hotline complaint regarding whether federal funds were properly used to construct the new Spokane County wastewater treatment facility in accordance with 40 CFR 35, Subpart K.

  14. Long-term Planning for Sustainable Water and Wastewater Infrastructure in Wellpinit, Washington, for the Spokane Tribe of Indians

    Science.gov (United States)

    The Spokane Tribe initiated a long-term planning process for a water and wastewater infrastructure system that can support the tribe’s goals to add compact, mixed-use development in the town of Wellpinit.

  15. Ecological indicators of water quality in the Spokane River, Idaho and Washington, 1998 and 1999

    Science.gov (United States)

    MacCoy, Dorene E.; Maret, Terry R.

    2003-01-01

    A water-quality investigation of the Spokane River was completed during summer low-flow conditions in 1998 and 1999 as part of the USGS NAWQA Program, in cooperation with the WDOE. (Abbreviations used in this report are defined on the last page.) Samples for analyses of water chemistry; bed sediment; aquatic communities (fish, macroinvertebrates, and algae); contaminants in tissue (fish and macroinvertebrates); and associated measures of habitat were collected at six sites downstream from Coeur d’Alene Lake between river miles 63 and 100. These data provided baseline information to evaluate the water-quality status of the Spokane River and can be used to determine the ecological risk to aquatic organisms from contaminants.

  16. Metropolitan Spokane Region Water Resources Study. Appendix E. Environment and Recreation

    Science.gov (United States)

    1976-01-01

    Q ATER:a-ESOURCE8 STUDY pet ropoli an no APPENDIX E En- go n a o -Ir LIST OF REPORTS AND APPENDICES REPORTS Summary Report Technical Report APPEND...AnimalsSmall Animals 315.52- 1Muskrats 315.52- 2Mink 315.52- 2 Beaver 315.52- 3Racoon 315.52- 3 Otter 315.52- 3Bobcat 315.52- 3Aquatic Game Birds 315.52...racoon, otter and bobcats ar- present in varying numbers in the etudy area. Fur-bearing animals are generally abundant throughout the en- tire Spokane

  17. Clinical manifestations of human coronavirus NL63 infection in children in Taiwan

    NARCIS (Netherlands)

    Wu, Ping-Sheng; Chang, Luan-Yin; Berkhout, B.; van der Hoek, L.; Lu, Chun-Yi; Kao, Chuan-Liang; Lee, Ping-Ing; Shao, Pei-Lan; Lee, Chin-Yun; Huang, Fu-Yuan; Huang, Li-Min

    2008-01-01

    Human coronavirus NL63 (HCoV-NL63) is a global respiratory tract pathogen; however, the epidemiology of this virus in subtropical area is not well known. To evaluate the epidemics and disease spectrum of HCoV-NL63 infection in children in Taiwan, we prospectively screened children admitted to the

  18. Named Entity Recognition in a Hungarian NL Based QA System

    Science.gov (United States)

    Tikkl, Domonkos; Szidarovszky, P. Ferenc; Kardkovacs, Zsolt T.; Magyar, Gábor

    In WoW project our purpose is to create a complex search interface with the following features: search in the deep web content of contracted partners' databases, processing Hungarian natural language (NL) questions and transforming them to SQL queries for database access, image search supported by a visual thesaurus that describes in a structural form the visual content of images (also in Hungarian). This paper primarily focuses on a particular problem of question processing task: the entity recognition. Before going into details we give a short overview of the project's aims.

  19. Hobo Orator Union: Class Composition and the Spokane Free Speech Fight of the Industrial Workers of the World

    Science.gov (United States)

    May, Matthew S.

    2011-01-01

    From 1909 to 1910, the public performance of soap-box oratory began to effect dramatic changes in the composition of migrant workers throughout the Pacific Northwest. Municipal authorities in Spokane attempted to curb the formation of a union of hobo orators by outlawing public speech-making within the city fire limits. The ensuing confrontation…

  20. 77 FR 12873 - Draft Environmental Impact Statement for the Proposed Spokane Tribe of Indians West Plains Casino...

    Science.gov (United States)

    2012-03-02

    ... structure, site retail, commercial building, tribal cultural center, and police/ fire station within the... Main Street, Spokane, Washington 99201. The DEIS is also available online at: http://www.westplainseis... shown in the ADDRESSES section of this notice, during regular business hours, 8 a.m. to 4:30 p.m...

  1. Potential Hydroelectric Power Upriver Dam: City of Spokane Department of Utilities Water Division

    Energy Technology Data Exchange (ETDEWEB)

    1979-02-01

    The technical, economic, environmental and institutional feasibility of increasing the power generation capacity of the City of Spokane's Upriver Dam Complex by installing additional generating facilities and/or modifying existing facilities were studied. It is proposed that the existing powerhouse be uprated from 3.9 to 4.5 MW and that a new powerhouse be constructed with two 4.5 MW turbines to provide an annual additional energy production of 62.3 million kWh. No adverse environmental or safety effects are foreseen, the socio-institutional impacts will be beneficial, there is a market for the power produced, and the benefit/cost ratio is advantageous. (LCL)

  2. The BSID-II-NL for assessing children with specific impairments

    NARCIS (Netherlands)

    Ruiter, Selma Anne José

    2007-01-01

    Abstract In this doctoral thesis the Dutch standardization and validation of the Bayley Scales of Infant Development – Second Edition (BSID-II-NL) and its adapted versions for use with children with specific impairmens are presented. The BSID-II-NL is a standardized and norm-referenced instrument to

  3. Reduced Fertility in Male Mice Deficient in the Zinc Metallopeptidase NL1

    Science.gov (United States)

    Carpentier, Mélanie; Guillemette, Christine; Bailey, Janice L.; Boileau, Guy; Jeannotte, Lucie; DesGroseillers, Luc; Charron, Jean

    2004-01-01

    Members of the M13 family of zinc metalloendopeptidases have been shown to play critical roles in the metabolism of various neuropeptides and peptide hormones, and they have been identified as important therapeutic targets. Recently, a mouse NL1 protein, a novel member of the family, was identified and shown to be expressed mainly in the testis as a secreted protein. To define its physiological role(s), we used a gene targeting strategy to disrupt the endogenous murine Nl1 gene by homologous recombination and generate Nl1 mutant mice. The Nl1−/− mice were viable and developed normally, suggesting that zygotic expression of Nl1 is not required for development. However, Nl1−/− males produced smaller litters than their wild-type siblings, indicating specific male fertility problems. Reduced fertility may be explained by two impaired processes, decreased egg fertilization and perturbed early development of fertilized eggs. These two phenotypes did not result from gross anatomical modifications of the testis or from impaired spermatogenesis. Basic sperm parameters were also normal. Thus, our findings suggest that one of the roles of NL1 in mice is related to sperm function and that NL1 modulates the processes of fertilization and early embryonic development in vivo. PMID:15121861

  4. Tekenradar.nl, een webplatform over tekenbeten en de ziekte van Lyme

    NARCIS (Netherlands)

    Harms, M.G.; Fonville, M.; Vliet, van A.J.H.; Bennema, S.; Hofhuis, A.; Beaujean, D.; Sprong, H.; Pelt, van W.; Wijngaard, van den C.C.

    2014-01-01

    Tekenradar.nl is een webplatform voor onderzoek naar teken en tekenoverdraagbare aandoeningen zoals de ziekte van Lyme. Het RIVM en Wageningen University hebben de website in 2012 gezamenlijk opgericht. Tekenradar.nl geeft informatie over tekenbeten en de ziekte van Lyme en een actuele voorspelling

  5. Radon and remedial action in Spokane River Valley residences: an interim report

    International Nuclear Information System (INIS)

    Turk, B.H.; Prill, R.J.; Fisk, W.J.; Grimsrud, D.T.; Moed, B.A.; Sextro, R.G.

    1986-03-01

    Fifty-six percent of 46 residences monitored in the Spokane River Valley in eastern Washington/northern Idaho have indoor radon concentrations above the National Council for Radiation Protection (NCRP) guidelines of 8 pCi/1. Indoor levels were over 20 pCi/1 in eight homes, and ranged up to 132 pCi/1 in one house. Radon concentrations declined by factors of 4 to 38 during summer months. Measurements of soil emanation rates, domestic water supply concentrations, and building material flux rates indicate that diffusion of radon does not significantly contribute to the high concentrations observed. Rather, radon entry is dominated by pressure-driven bulk soil gas transport, aggravated by the local subsurface soil composition and structure. A variety of radon control strategies are being evaluated in 14 of these homes. Sub-surface ventilation by depressurization and overpressurization, basement overpressurization, and crawlspace ventilation are capable of successfully reducing radon levels below 5 pCi/1 in these homes. House ventilation is appropriate in buildings with low-moderate concentrations, while sealing of cracks has been relatively ineffective

  6. Small-scale geodiversity and dirt road management, Ede (NL)

    Science.gov (United States)

    van den Ancker, Hanneke; Jungerius, Pieter Dirk

    2016-04-01

    A large part of the countryside roads on the Pleistocene sands of The Netherlands are dirt roads. Most are footpaths, but a small percentage are relatively heavily used by motorized vehicles. These latter roads are a cause subject of debate. Puddles and potholes develop during periods of wet weather, while dust whirls from the roads form during spells of dry weather as do washboard ripples. They cause problems for people living along these roads and tourists (walkers and bikers. The community of Ede (NL), like many other communities on the sand, wants to keep its 80 km of dirt roads because of the natural values they harbour as well as for their characteristic landscape quality and cultural heritage value. A part of the dirt roads in Ede is heavily used. In 2009, the community of Ede developed a decision model to support management of the dirt roads. Ede acknowledges that each dirt road is unique and asks for a tailor-made solution. Road maintenance measures include grading, making a camber, digging pits, applying loam or sandy loam. If problems become too large, one-way traffic can be an option. In more and more cases the dirt roads are barred for motorized through traffic (Gemeente Ede, 2009). As a reconnaissance we have studied the dirt roads of the Horabos/Horalaan over the last year. Incidentally we looked at other parts of the main Horalaan and the footpaths in the adjacent forest of Hoekelum. All dirt roads lie near the top of a Saalian push-moraine in which the upper course of dry valleys are present. Some results of the reconnaissance: - Most dirt roads sections in the Horabos lie lower than the surrounding terrain; - The problems develop in a short period of time during special weather conditions; - Certain dirt road sections e.g. those sections crossing a slight depression are quickly developing potholes; - Even a small slope of the road (car traffic improves the infiltration in the road, and reduces the run-off to other the road sections to nearly zero

  7. Epidemiology of human coronavirus NL63 infection among hospitalized patients with pneumonia in Taiwan

    Directory of Open Access Journals (Sweden)

    Su-Hua Huang

    2017-12-01

    Full Text Available Background/Purpose: Human coronavirus (HCoV NL63 is recognized in association with upper or lower respiratory tract illnesses in children. This study surveyed the prevalence of HCoV-NL63 and influenza viruses in patients with influenza-like illness in Taiwan during 2010–2011. Methods: Throat samples from 107 hospitalized patients with pneumonia and 175 outpatients with influenza-like illness were examined using real-time polymerase chain reaction assays with virus-specific primers, and then virus-positive specimens were confirmed by sequencing the polymerase chain reaction products. Results: HCoV-NL63 infection was identified in 8.4% (9/107 of hospitalized patients with pneumonia, but not found in outpatients with influenza-like illness. Age distribution of HCoV-NL63 infection in hospitalized patients with pneumonia indicated that the group aged 16–25 years (20% had the highest positive rate compared with the other groups, and exhibited a similar age-specific pattern to influenza A/H1N1 infection, but not influenza A/H3N2 and B infections in hospitalized patients. Seasonal prevalence of HCoV-NL63 infection was late winter, overlapping the highest peak of the influenza A/H1N1 epidemic during December 2010 to March 2011 in Taiwan. Co-infection of HCoV-NL63 and influenza A/H1N1 was detected in three hospitalized patients. Clinical manifestation analysis indicated that the main symptoms for HCoV-NL63 infection included fever (88.9%, cough (77.8%, and pneumonia (100%. Co-infection caused significantly higher rates of breathing difficulties, cough, and sore throat than those of single infection with HCoV-NL63 and influenza A/H1N1. Phylogenetic analysis indicated a low level of heterogeneity between Taiwan and global HCoV-NL63 strains. Conclusion: Understanding epidemiology of HCoV-NL63 in Taiwan provides an insight for worldwide surveillance of HCoV-NL63 infection. Keywords: age distribution, human coronavirus NL63, phylogenetic analysis

  8. Crystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptor

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Kailang; Li, Weikai; Peng, Guiqing; Li, Fang; (Harvard-Med); (UMM-MED)

    2010-03-04

    NL63 coronavirus (NL63-CoV), a prevalent human respiratory virus, is the only group I coronavirus known to use angiotensin-converting enzyme 2 (ACE2) as its receptor. Incidentally, ACE2 is also used by group II SARS coronavirus (SARS-CoV). We investigated how different groups of coronaviruses recognize the same receptor, whereas homologous group I coronaviruses recognize different receptors. We determined the crystal structure of NL63-CoV spike protein receptor-binding domain (RBD) complexed with human ACE2. NL63-CoV RBD has a novel {beta}-sandwich core structure consisting of 2 layers of {beta}-sheets, presenting 3 discontinuous receptor-binding motifs (RBMs) to bind ACE2. NL63-CoV and SARS-CoV have no structural homology in RBD cores or RBMs; yet the 2 viruses recognize common ACE2 regions, largely because of a 'virus-binding hotspot' on ACE2. Among group I coronaviruses, RBD cores are conserved but RBMs are variable, explaining how these viruses recognize different receptors. These results provide a structural basis for understanding viral evolution and virus-receptor interactions.

  9. A Rule-Based System Implementing a Method for Translating FOL Formulas into NL Sentences

    Science.gov (United States)

    Mpagouli, Aikaterini; Hatzilygeroudis, Ioannis

    In this paper, we mainly present the implementation of a system that translates first order logic (FOL) formulas into natural language (NL) sentences. The motivation comes from an intelligent tutoring system teaching logic as a knowledge representation language, where it is used as a means for feedback to the students-users. FOL to NL conversion is achieved by using a rule-based approach, where we exploit the pattern matching capabilities of rules. So, the system consists of rule-based modules corresponding to the phases of our translation methodology. Facts are used in a lexicon providing lexical and grammatical information that helps in producing the NL sentences. The whole system is implemented in Jess, a java-implemented rule-based programming tool. Experimental results confirm the success of our choices.

  10. Psychometric properties and validity of the Dutch Inventory of Personality Organization (IPO-NL).

    Science.gov (United States)

    Berghuis, Han; Kamphuis, Jan H; Boedijn, Gerard; Verheul, Roel

    2009-01-01

    This study investigated the psychometric qualities and validity of a Dutch translation of the Inventory of Personality Organization (IPO-NL) in a heterogeneous sample of 371 psychiatric patients and a sample of 181 normal controls. Results show good internal consistency and test-retest reliability. Exploratory factor analyses did not replicate its proposed five-factor structure, but suggested a four-factor structure instead. The IPO-NL appeared to have good concurrent validity across populations, and good convergent validity in terms of associations with measures of psychological distress and personality pathology severity. Taken together, the IPO-NL appears to be a useful instrument for evaluating general personality pathology for clinical practice. Future studies may further articulate its proposed subscales.

  11. Protein crystallization in a 100 nl solution with new stirring equipment

    International Nuclear Information System (INIS)

    Maki, S.; Murai, R.; Yoshikawa, H. Y.; Kitatani, T.; Nakata, S.; Kawahara, H.; Hasenaka, H.; Kobayashi, A.; Okada, S.; Sugiyama, S.; Adachi, H.; Matsumura, H.; Takano, K.; Murakami, S.; Inoue, T.; Sasaki, T.; Mori, Y.

    2008-01-01

    To investigate quantitatively the effects of stirring on protein crystallization, a new stirring system which can agitate a protein solution, ∼100 nl, by providing Hagen–Poiseuille flow has been successfully developed. To investigate quantitatively the effects of stirring on protein crystallization, a new stirring system which can agitate a protein solution, ∼100 nl, by providing Hagen–Poiseuille flow has been successfully developed. In addition, this new stirring system provides flow with a well defined pattern and velocity. Using this system, hen egg-white lysozyme was crystallized in 100–200 nl solutions while being stirred. The optimum stirring conditions for lysozyme crystals have been explored by evaluating the Reynolds (Re) number and the crystals obtained. Intermittent flow, as well as a low Re number, was found to contribute significantly to the growth of a smaller number of larger crystals

  12. Executive functioning in college students: Evaluation of the Dutch Executive Function Index (EFI-NL)

    NARCIS (Netherlands)

    Janssen, G.T.L.; Mey, H.R.A. De; Egger, J.I.M.

    2009-01-01

    The Executive Function Index (EFI) is a short self-report questionnaire for the assessment of executive functions (EF) as encountered in daily life. The aim of the present study is to examine the psychometric properties of the Dutch version of the EFI (EFI-NL) in a college student sample (N = 376).

  13. UltiMatch-NL: a Web service matchmaker based on multiple semantic filters.

    Science.gov (United States)

    Mohebbi, Keyvan; Ibrahim, Suhaimi; Zamani, Mazdak; Khezrian, Mojtaba

    2014-01-01

    In this paper, a Semantic Web service matchmaker called UltiMatch-NL is presented. UltiMatch-NL applies two filters namely Signature-based and Description-based on different abstraction levels of a service profile to achieve more accurate results. More specifically, the proposed filters rely on semantic knowledge to extract the similarity between a given pair of service descriptions. Thus it is a further step towards fully automated Web service discovery via making this process more semantic-aware. In addition, a new technique is proposed to weight and combine the results of different filters of UltiMatch-NL, automatically. Moreover, an innovative approach is introduced to predict the relevance of requests and Web services and eliminate the need for setting a threshold value of similarity. In order to evaluate UltiMatch-NL, the repository of OWLS-TC is used. The performance evaluation based on standard measures from the information retrieval field shows that semantic matching of OWL-S services can be significantly improved by incorporating designed matching filters.

  14. Possible involvement of infection with human coronavirus 229E, but not NL63, in Kawasaki disease.

    Science.gov (United States)

    Shirato, Kazuya; Imada, Yoshio; Kawase, Miyuki; Nakagaki, Keiko; Matsuyama, Shutoku; Taguchi, Fumihiro

    2014-12-01

    Although human coronavirus (HCoV)-NL63 was once considered a possible causative agent of Kawasaki disease based on RT-PCR analyses, subsequent studies could not confirm the result. In this study, this possibility was explored using serological tests. To evaluate the role of HCoV infection in patients with Kawasaki disease, immunofluorescence assays and virus neutralizing tests were performed. Paired serum samples were obtained from patients with Kawasaki disease who had not been treated with γ-globulin. HCoV-NL63 and two antigenically different isolates of HCoV-229E (ATCC-VR740 and a new isolate, Sendai-H) were examined as controls. Immunofluorescence assays detected no difference in HCoV-NL63 antibody positivity between the patients with Kawasaki disease and controls, whereas the rate of HCoV-229E antibody positivity was higher in the patients with Kawasaki disease than that in controls. The neutralizing tests revealed no difference in seropositivity between the acute and recovery phases of patients with Kawasaki disease for the two HCoV-229Es. However, the Kawasaki disease specimens obtained from patients in recovery phase displayed significantly higher positivity for Sendai-H, but not for ATCC-VR740, as compared to the controls. The serological test supported no involvement of HCoV-NL63 but suggested the possible involvement of HCoV-229E in the development of Kawasaki disease. © 2014 Wiley Periodicals, Inc.

  15. The dominance of human coronavirus OC43 and NL63 infections in infants

    NARCIS (Netherlands)

    Dijkman, Ronald; Jebbink, Maarten F.; Gaunt, Eleanor; Rossen, John W. A.; Templeton, Kate E.; Kuijpers, Taco W.; van der Hoek, Lia

    2012-01-01

    Background: It is unknown to what extent the human coronaviruses (HCoVs) OC43, HKU1, 229E and NL63 infect healthy children. Frequencies of infections are only known for hospitalized children. Objectives: Comparing infection frequencies in children who have mild infections with frequencies in

  16. Plaque assay for human coronavirus NL63 using human colon carcinoma cells

    Directory of Open Access Journals (Sweden)

    Drosten Christian

    2008-11-01

    Full Text Available Abstract Background Coronaviruses cause a broad range of diseases in animals and humans. Human coronavirus (hCoV NL63 is associated with up to 10% of common colds. Viral plaque assays enable the characterization of virus infectivity and allow for purifying virus stock solutions. They are essential for drug screening. Hitherto used cell cultures for hCoV-NL63 show low levels of virus replication and weak and diffuse cytopathogenic effects. It has not yet been possible to establish practicable plaque assays for this important human pathogen. Results 12 different cell cultures were tested for susceptibility to hCoV-NL63 infection. Human colon carcinoma cells (CaCo-2 replicated virus more than 100 fold more efficiently than commonly used African green monkey kidney cells (LLC-MK2. CaCo-2 cells showed cytopathogenic effects 4 days post infection. Avicel, agarose and carboxymethyl-cellulose overlays proved suitable for plaque assays. Best results were achieved with Avicel, which produced large and clear plaques from the 4th day of infection. The utility of plaque assays with agrose overlay was demonstrated for purifying virus, thereby increasing viral infectivity by 1 log 10 PFU/mL. Conclusion CaCo-2 cells support hCoV-NL63 better than LLC-MK2 cells and enable cytopathogenic plaque assays. Avicel overlay is favourable for plaque quantification, and agarose overlay is preferred for plaque purification. HCoV-NL63 virus stock of increased infectivity will be beneficial in antiviral screening, animal modelling of disease, and other experimental tasks.

  17. Correlation and relativistic effects for the 4f-nl and 5p-nl multipole transitions in Er-like tungsten

    International Nuclear Information System (INIS)

    Safronova, U. I.; Safronova, A. S.

    2011-01-01

    Wavelengths, transition rates, and line strengths are calculated for the multipole (E1, M1, E2, M2, E3, and M3) transitions between the excited [Cd]4f 13 5p 6 nl, [Cd]4f 14 5p 5 nl configurations and the ground [Cd]4f 14 5p 6 state in Er-like W 6+ ion ([Cd]=[Kr]4d 10 5s 2 ). In particular, the relativistic many-body perturbation theory (RMBPT), including the Breit interaction, is used to evaluate energies and transition rates for multipole transitions in this hole-particle system. This method is based on the relativistic many-body perturbation theory that agrees with multiconfiguration Dirac-Fock (MCDF) calculations in lowest order, and includes all second-order correlation corrections and corrections from negative-energy states. The calculations start from a [Cd]4f 14 5p 6 Dirac-Fock (DF) potential. First-order perturbation theory is used to obtain intermediate-coupling coefficients, and second-order RMBPT is used to determine the multipole matrix elements needed for calculations of other atomic properties such as line strengths and transition rates. In addition, core multipole polarizability is evaluated in random-phase and DF approximations. The comparison with available data is demonstrated.

  18. Impacts of future changes on groundwater recharge and flow in highly-connected river-aquifer systems: A case study of the Spokane Valley-Rathdrum Prairie Aquifer

    Science.gov (United States)

    Nguyen, T. T.; Baxter, H.; Barber, M. E.; Hossain, A.; Orr, C. H.; Adam, J. C.

    2013-12-01

    The Spokane, Washington-Coeur d'Alene, Idaho Corridor is well-known for its Spokane Valley-Rathdrum Prairie (SVRP) Aquifer which is a sole source of drinking water for more than 500,000 people. The aquifer is highly connected to the Spokane River and responds very fast to natural and human perturbations, making it relatively vulnerable to climate and anthropogenic changes in future decades. Recent studies have indicated a decline in minimum daily flow in the Spokane River in the last 100 years, while projecting an increase in cool-season precipitation into the future. We investigated the potential impacts of these projected future climate-driven hydrologic changes on groundwater recharge and flow in the SVRP. A distributed, physically-based hydrological model, the Precipitation Runoff Modeling System (PRMS), was coupled with an existing Modular three-dimensional finite-difference ground-water model (MODFLOW) to have better estimates of recharge into the SVRP as well as the interaction of surface water and groundwater. The couple model was calibrated and validated at a daily time-step within the Model-Independent Parameter Estimation (PEST) framework using 16 years of both observed streamflow and observed well data (1990 - 2005). To assess future climate change impacts, statistically downscaled climate projections of temperature and precipitation between 2010 and 2050 from four general circulation models were used. The results from the coupled model provide insight on the interplay between snowmelt, streamflow, groundwater recharge and discharge in such a highly-connected system. Moreover, the relative sensitivities of groundwater recharge and flow with respect to changes in climate and land cover are also examined. These results can be used as good references for long term water resources management and planning in the region.

  19. Confirmatory Factor Analysis of the Dutch Version of the Wechsler Memory Scale-Fourth Edition (WMS-IV-NL)

    NARCIS (Netherlands)

    Bouman, Z.; Hendriks, M.P.; Kerkmeer, M.C.; Kessels, R.P.C.; Aldenkamp, A.P.

    2015-01-01

    The latent factor structure of the Dutch version of the Wechsler Memory Scale-Fourth Edition (WMS-IV-NL) was examined with a series of confirmatory factor analyses. As part of the Dutch standardization, 1,188 healthy participants completed the WMS-IV-NL. Four models were tested for the Adult Battery

  20. Automated Generation of OCL Constraints: NL based Approach vs Pattern Based Approach

    Directory of Open Access Journals (Sweden)

    IMRAN SARWAR BAJWA

    2017-04-01

    Full Text Available This paper presents an approach used for automated generations of software constraints. In this model, the SBVR (Semantics of Business Vocabulary and Rules based semi-formal representation is obtained from the syntactic and semantic analysis of a NL (Natural Language (such as English sentence. A SBVR representation is easy to translate to other formal languages as SBVR is based on higher-order logic like other formal languages such as OCL (Object Constraint Language. The proposed model endows with a systematic and powerful system of incorporating NL knowledge on the formal languages. A prototype is constructed in Java (an Eclipse plug-in as a proof of the concept. The performance was tested for a few sample texts taken from existing research thesis reports and books

  1. How to Assist Formalization of NL Regulations: Lessons from Business Rules Acquisition Experiments

    OpenAIRE

    Nazarenko , Adeline

    2013-01-01

    International audience; Decision systems usually rely on a set of business rules that describe the expected behavior of a system or an organization and that determine the decisions to be taken in different situations. However, rule acquisition is often the bottleneck that hinders the development of decision systems. When these rules are based on regulations written in Natural Language (NL), one solution is to derive formal business rules from the source documents. This approach also allows ch...

  2. Wbp2nl has a developmental role in establishing neural and non-neural ectodermal fates.

    Science.gov (United States)

    Marchak, Alexander; Grant, Paaqua A; Neilson, Karen M; Datta Majumdar, Himani; Yaklichkin, Sergey; Johnson, Diana; Moody, Sally A

    2017-09-01

    In many animals, maternally synthesized mRNAs are critical for primary germ layer formation. In Xenopus, several maternal mRNAs are enriched in the animal blastomere progenitors of the embryonic ectoderm. We previously identified one of these, WW-domain binding protein 2 N-terminal like (wbp2nl), that others previously characterized as a sperm protein (PAWP) that promotes meiotic resumption. Herein we demonstrate that it has an additional developmental role in regionalizing the embryonic ectoderm. Knock-down of Wbp2nl in the dorsal ectoderm reduced cranial placode and neural crest gene expression domains and expanded neural plate domains; knock-down in ventral ectoderm reduced epidermal gene expression. Conversely, increasing levels of Wbp2nl in the neural plate induced ectopic epidermal and neural crest gene expression and repressed many neural plate and cranial placode genes. The effects in the neural plate appear to be mediated, at least in part, by down-regulating chd, a BMP antagonist. Because the cellular function of Wbp2nl is not known, we mutated several predicted motifs. Expressing mutated proteins in embryos showed that a putative phosphorylation site at Thr45 and an α-helix in the PH-G domain are required to ectopically induce epidermal and neural crest genes in the neural plate. An intact YAP-binding motif also is required for ectopic epidermal gene expression as well as for down-regulating chd. This work reveals novel developmental roles for a cytoplasmic protein that promotes epidermal and neural crest formation at the expense of neural ectoderm. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Reduction in open field activity in the absence of memory deficits in the AppNL-G-F knock-in mouse model of Alzheimer's disease.

    Science.gov (United States)

    Whyte, Lauren S; Hemsley, Kim M; Lau, Adeline A; Hassiotis, Sofia; Saito, Takashi; Saido, Takaomi C; Hopwood, John J; Sargeant, Timothy J

    2018-01-15

    The recent development of knock-in mouse models of Alzheimer's disease provides distinct advantages over traditional transgenic mouse models that rely on over-expression of amyloid precursor protein. Two such knock-in models that have recently been widely adopted by Alzheimer's researchers are the App NL-F and App NL-G-F mice. This study aimed to further characterise the behavioural phenotype and amyloid plaque distribution of App NL-G-F/NL-G-F (C57BL/6J background) mice at six-months of age. An attempt to replicate a previous study that observed deficits in working memory in the Y-maze, showed no difference between App NL-G-F/NL-G-F and wild-type mice. Further assessment of these mice using the novel object recognition test and Morris water maze also revealed no differences between App NL-G-F/NL-G-F and wild-type mice. Despite a lack of demonstrated cognitive deficits, we report a reduction in locomotor/exploratory activity in an open field. Histological examination of App NL-G-F/NL-G-F mice showed widespread distribution of amyloid plaques at this age. We conclude that whilst at six-months of age, memory deficits are not sufficiently robust to be replicated in varying environments, amyloid plaque burden is significant in App NL-G-F/NL-G-F knock-in brain. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Validation of the Dutch language version of the Safety Attitudes Questionnaire (SAQ-NL).

    Science.gov (United States)

    Haerkens, Marck Htm; van Leeuwen, Wouter; Sexton, J Bryan; Pickkers, Peter; van der Hoeven, Johannes G

    2016-08-15

    As the first objective of caring for patients is to do no harm, patient safety is a priority in delivering clinical care. An essential component of safe care in a clinical department is its safety climate. Safety climate correlates with safety-specific behaviour, injury rates, and accidents. Safety climate in healthcare can be assessed by the Safety Attitudes Questionnaire (SAQ), which provides insight by scoring six dimensions: Teamwork Climate, Job Satisfaction, Safety Climate, Stress Recognition, Working Conditions and Perceptions of Management. The objective of this study was to assess the psychometric properties of the Dutch language version of the SAQ in a variety of clinical departments in Dutch hospitals. The Dutch version (SAQ-NL) of the SAQ was back translated, and analyzed for semantic characteristics and content. From October 2010 to November 2015 SAQ-NL surveys were carried out in 17 departments in two university and seven large non-university teaching hospitals in the Netherlands, prior to a Crew Resource Management human factors intervention. Statistical analyses were used to examine response patterns, mean scores, correlations, internal consistency reliability and model fit. Cronbach's α's and inter-item correlations were calculated to examine internal consistency reliability. One thousand three hundred fourteen completed questionnaires were returned from 2113 administered to health care workers, resulting in a response rate of 62 %. Confirmatory Factor Analysis revealed the 6-factor structure fit the data adequately. Response patterns were similar for professional positions, departments, physicians and nurses, and university and non-university teaching hospitals. The SAQ-NL showed strong internal consistency (α = .87). Exploratory analysis revealed differences in scores on the SAQ dimensions when comparing different professional positions, when comparing physicians to nurses and when comparing university to non-university hospitals. The SAQ-NL

  5. Outcomes of senior reach gatekeeper referrals: comparison of the Spokane gatekeeper program, Colorado Senior Reach, and Mid-Kansas Senior Outreach.

    Science.gov (United States)

    Bartsch, David A; Rodgers, Vicki K; Strong, Don

    2013-01-01

    Outcomes of older adults referred for care management and mental health services through the senior reach gatekeeper model of case finding were examined in this study and compared with the Spokane gatekeeper model Colorado Senior Reach and the Mid-Kansas Senior Outreach (MKSO) programs are the two Senior Reach Gatekeeper programs modeled after the Spokane program, employing the same community education and gatekeeper model and with mental health treatment for elderly adults in need of support. The three mature programs were compared on seniors served isolation, and depression ratings. Nontraditional community gatekeepers were trained and referred seniors in need. Findings indicate that individuals served by the two Senior Reach Gatekeeper programs demonstrated significant improvements. Isolation indicators such as social isolation decreased and depression symptoms and suicide ideation also decreased. These findings for two Senior Reach Gatekeeper programs demonstrate that the gatekeeper approach to training community partners worked in referring at-risk seniors in need in meeting their needs, and in having a positive impact on their lives.

  6. Evidence supporting a zoonotic origin of human coronavirus strain NL63.

    Science.gov (United States)

    Huynh, Jeremy; Li, Shimena; Yount, Boyd; Smith, Alexander; Sturges, Leslie; Olsen, John C; Nagel, Juliet; Johnson, Joshua B; Agnihothram, Sudhakar; Gates, J Edward; Frieman, Matthew B; Baric, Ralph S; Donaldson, Eric F

    2012-12-01

    The relationship between bats and coronaviruses (CoVs) has received considerable attention since the severe acute respiratory syndrome (SARS)-like CoV was identified in the Chinese horseshoe bat (Rhinolophidae) in 2005. Since then, several bats throughout the world have been shown to shed CoV sequences, and presumably CoVs, in the feces; however, no bat CoVs have been isolated from nature. Moreover, there are very few bat cell lines or reagents available for investigating CoV replication in bat cells or for isolating bat CoVs adapted to specific bat species. Here, we show by molecular clock analysis that alphacoronavirus (α-CoV) sequences derived from the North American tricolored bat (Perimyotis subflavus) are predicted to share common ancestry with human CoV (HCoV)-NL63, with the most recent common ancestor between these viruses occurring approximately 563 to 822 years ago. Further, we developed immortalized bat cell lines from the lungs of this bat species to determine if these cells were capable of supporting infection with HCoVs. While SARS-CoV, mouse-adapted SARS-CoV (MA15), and chimeric SARS-CoVs bearing the spike genes of early human strains replicated inefficiently, HCoV-NL63 replicated for multiple passages in the immortalized lung cells from this bat species. These observations support the hypothesis that human CoVs are capable of establishing zoonotic-reverse zoonotic transmission cycles that may allow some CoVs to readily circulate and exchange genetic material between strains found in bats and other mammals, including humans.

  7. Ras Labs.-CASIS-ISS NL experiment for synthetic muscle: resistance to ionizing radiation

    Science.gov (United States)

    Rasmussen, Lenore; Sandberg, Eric; Albers, Leila N.; Rodriguez, Simone; Gentile, Charles A.; Meixler, Lewis D.; Ascione, George; Hitchner, Robert; Taylor, James; Hoffman, Dan; Cylinder, David; Moy, Leon; Mark, Patrick S.; Prillaman, Daniel L.; Nordarse, Robert; Menegus, Michael J.; Ratto, Jo Ann; Thellen, Christopher; Froio, Danielle; Furlong, Cosme; Razavi, Payam; Valenza, Logan; Hablani, Surbhi; Fuerst, Tyler; Gallucci, Sergio; Blocher, Whitney; Liffland, Stephanie

    2016-04-01

    In anticipation of deep space travel, new materials are being explored to assist and relieve humans in dangerous environments, such as high radiation, extreme temperature, and extreme pressure. Ras Labs Synthetic Muscle - electroactive polymers (EAPs) that contract and expand at low voltages - which mimic the unique gentle-yet-strong nature of human tissue, is a potential asset to manned space travel through protective gear and human assist robotics and for unmanned space exploration through deep space. Generation 3 Synthetic Muscle was proven to be resistant to extreme temperatures, and there were indications that these materials may also be radiation resistant. The purpose of the Ras Labs-CASIS-ISS Experiment is to test the radiation resistivity of the third and fourth generation of these EAPs, as well as to make them even more radiation resistant or radiation hardened. On Earth, exposure of the Generation 3 and Generation 4 EAPs to a Cs-137 radiation source for 47.8 hours with a total dose of 305.931 kRad of gamma radiation was performed at the US Department of Energy's Princeton Plasma Physics Laboratory (PPPL) at Princeton University, followed by pH, peroxide, Shore Hardness Durometry, and electroactivity testing to determine the inherent radiation resistivity of these contractile EAPs and to determine whether the EAPs could be made even more radiation resistant through the application of appropriate additives and coatings. The on Earth preliminary tests determined that selected Ras Labs EAPs were not only inherently radiation resistant, but with the appropriate coatings and additives, could be made even more radiation resistant. Gforce testing to over 10 G's was performed at US Army's ARDEC Labs, with excellent results, in preparation for space flight to the International Space Station National Laboratory (ISS-NL). Selected samples of Generation 3 and Generation 4 Synthetic Muscle™, with various additives and coatings, were launched to the ISS-NL on April

  8. Confirmatory Factor Analysis of the Dutch Version of the Wechsler Memory Scale-Fourth Edition (WMS-IV-NL).

    Science.gov (United States)

    Bouman, Zita; Hendriks, Marc P H; Kerkmeer, Margreet C; Kessels, Roy P C; Aldenkamp, Albert P

    2015-05-01

    The latent factor structure of the Dutch version of the Wechsler Memory Scale-Fourth Edition (WMS-IV-NL) was examined with a series of confirmatory factor analyses. As part of the Dutch standardization, 1,188 healthy participants completed the WMS-IV-NL. Four models were tested for the Adult Battery (16-69 years; N = 699), and two models were tested for the Older Adult Battery (65-90 years; N = 489). Results corroborated the presence of three WMS-IV-NL factors in the Adult Battery consisting of Auditory Memory, Visual Memory, and Visual Working Memory. A two-factor model (consisting of Auditory Memory and Visual Memory) provided the best fit for the data of the Older Adult Battery. These findings provide evidence for the structural validity of the WMS-IV-NL, and further support the psychometric integrity of the WMS-IV. © The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  9. Lifelong Learning and the E-Strategy of the Open University of the Netherlands: ou.nl

    NARCIS (Netherlands)

    Westera, Wim; Kalz, Marco

    2008-01-01

    Westera, W., & Kalz, M. (2008). Lifelong Learning and the E-Strategy of the Open University of the Netherlands: ou.nl. In J. Stratmann & M. Kerres (Eds.), E-strategy, Strategisches Informationsmanagement für Forschung und Lehre, Medien in de Wissenschaft Band 46 (pp. 253-266). Gesellschaft für

  10. Temporal stability of the Dutch version of the Wechsler Memory Scale - Fourth Edition (WMS-IV-NL)

    NARCIS (Netherlands)

    Bouman, Z.; Hendriks, M.P.H.; Aldenkamp, A.P.; Kessels, R.P.C.

    2015-01-01

    Objective: The Wechsler Memory Scale - Fourth Edition (WMS-IV) is one of the most widely used memory batteries. We examined the test–retest reliability, practice effects, and standardized regression-based (SRB) change norms for the Dutch version of the WMS-IV (WMS-IV-NL) after both short and long

  11. Association between lifestyle factors and quality-adjusted life years in the EPIC-NL cohort.

    Science.gov (United States)

    Fransen, Heidi P; May, Anne M; Beulens, Joline W J; Struijk, Ellen A; de Wit, G Ardine; Boer, Jolanda M A; Onland-Moret, N Charlotte; Hoekstra, Jeljer; van der Schouw, Yvonne T; Bueno-de-Mesquita, H Bas; Peeters, Petra H M

    2014-01-01

    The aim of our study was to relate four modifiable lifestyle factors (smoking status, body mass index, physical activity and diet) to health expectancy, using quality-adjusted life years (QALYs) in a prospective cohort study. Data of the prospective EPIC-NL study were used, including 33,066 healthy men and women aged 20-70 years at baseline (1993-7), followed until 31-12-2007 for occurrence of disease and death. Smoking status, body mass index, physical activity and adherence to a Mediterranean-style diet (excluding alcohol) were investigated separately and combined into a healthy lifestyle score, ranging from 0 to 4. QALYs were used as summary measure of healthy life expectancy, combining a person's life expectancy with a weight for quality of life when having a chronic disease. For lifestyle factors analyzed separately the number of years living longer in good health varied from 0.12 year to 0.84 year, after adjusting for covariates. A combination of the four lifestyle factors was positively associated with higher QALYs (P-trend healthy lifestyle score of 4 compared to a score of 0 was associated with almost a 2 years longer life in good health (1.75 QALYs [95% CI 1.37, 2.14]).

  12. Temporal Stability of the Dutch Version of the Wechsler Memory Scale-Fourth Edition (WMS-IV-NL).

    Science.gov (United States)

    Bouman, Zita; Hendriks, Marc P H; Aldenkamp, Albert P; Kessels, Roy P C

    2015-01-01

    The Wechsler Memory Scale-Fourth Edition (WMS-IV) is one of the most widely used memory batteries. We examined the test-retest reliability, practice effects, and standardized regression-based (SRB) change norms for the Dutch version of the WMS-IV (WMS-IV-NL) after both short and long retest intervals. The WMS-IV-NL was administered twice after either a short (M = 8.48 weeks, SD = 3.40 weeks, range = 3-16) or a long (M = 17.87 months, SD = 3.48, range = 12-24) retest interval in a sample of 234 healthy participants (M = 59.55 years, range = 16-90; 118 completed the Adult Battery; and 116 completed the Older Adult Battery). The test-retest reliability estimates varied across indexes. They were adequate to good after a short retest interval (ranging from .74 to .86), with the exception of the Visual Working Memory Index (r = .59), yet generally lower after a long retest interval (ranging from .56 to .77). Practice effects were only observed after a short retest interval (overall group mean gains up to 11 points), whereas no significant change in performance was found after a long retest interval. Furthermore, practice effect-adjusted SRB change norms were calculated for all WMS-IV-NL index scores. Overall, this study shows that the test-retest reliability of the WMS-IV-NL varied across indexes. Practice effects were observed after a short retest interval, but no evidence was found for practice effects after a long retest interval from one to two years. Finally, the SRB change norms were provided for the WMS-IV-NL.

  13. Sources, transport, and trends for selected trace metals and nutrients in the Coeur d'Alene and Spokane River Basins, Idaho, 1990-2013

    Science.gov (United States)

    Clark, Gregory M.; Mebane, Christopher A.

    2014-01-01

    Data collected at 18 streamflow-gaging and water-quality sampling sites in the Coeur d’Alene and Spokane River Basins of northern Idaho were used to estimate mean streamflow‑weighted concentrations and annual loads of total and dissolved cadmium, lead, and zinc, and total phosphorus (TP) and nitrogen (TN) for water years (WYs) 2009–13. Chronic Ambient Water Quality Criteria (AWQC) and AWQC ratios also were calculated to evaluate Idaho aquatic life criteria for chronic exposure to cadmium and zinc in streams. At four sites with a longer period of record, a Seasonal Kendall trend test was used to assess historical trends in the concentrations of total cadmium, lead, and zinc, and chronic AWQC ratios for cadmium and zinc during WYs 1990–2013.

  14. Polymorphism analysis of IL17RA gene to the IL17RA concentration and chronicity differences in nefritis lupus NL patients

    Directory of Open Access Journals (Sweden)

    Mahrus Ismail

    2014-12-01

    Full Text Available Nefritis lupus (NL is autoimmune disease and one of serious complication from Systemic Eritematosus Lupus (LES. Clinical manifestation of NL was variated, there are hematuria microscopic asymptomatic until renal failure. In addition of clinical manifestation, the NL disorder degree also measured from histopathological grade. Although, the mechanism that mixed up with pathogenesis of NL was known, however the cytokine also play a role to the disease process. The cytokine that assumpted have a role to the inflammation is IL-17RA, the increase production of IL-17RA influenced to the in-flammation and NL chronicity degree. The aim of this study to analyzed the relationship between polymorphism of IL-17RA gene, blood IL-17RA con-centration with the NL disorder degree. These studies were used cross sectional with control case design. The sample were used 40 patients consist NL pa-tients and Lupus patient without nephritis as a control. The polymorphisms of IL-17RA gene were investigated by using PCR method and gene sequence analysis. The alterations of allele frequency of IL-17RA gene were analyzed by bioinformatics method. The bloods IL-17RA concentration were in-vestigated by ELISA method. The NL chronicity degrees were investigated by NL histopathological grade. The hypothesis were proofed by data normality test and homogeneity test, Chi-square and Odds ratio, Spearman correlation by using SPSS 17.0 for windows. The result of showed that there are sig-nificantly different between IL-17RA gene mutant genotype frequency of NL patient (NL with the control patient with value OR 8.48. There are sig-nificantly different between G allele of IL-17RA gene of NL patient (case with the control patient with the value OR 4.17. There are no significantly di-fferent between IL-17RA concentrations of NL patient (case with the different chronicity value. There are positive correlation with the OR value 4.17 bet-ween IL-17RA concentrations with the chronicity value

  15. Efficient non-sterilized fermentation of biomass-derived xylose to lactic acid by a thermotolerant Bacillus coagulans NL01.

    Science.gov (United States)

    Ouyang, Jia; Cai, Cong; Chen, Hai; Jiang, Ting; Zheng, Zhaojuan

    2012-12-01

    Xylose is the major pentose and the second most abundant sugar in lignocellulosic feedstock. Its efficient utilization is regarded as a technical barrier to the commercial production of bulk chemicals from lignocellulosic biomass. This work aimed at evaluating the lactic acid production from the biomass-derived xylose using non-sterilized fermentation by Bacillus coagulans NL01. A maximum lactic acid concentration of about 75 g/L was achieved from xylose of 100 g/L after 72 h batch fermentation. Acetic acid and levulinic acid were identified as important inhibitors in xylose fermentation, which markedly reduced lactic acid productivity at 15 and 1.0 g/L, respectively. But low concentrations of formic acid (coagulans NL01, the same preference for glucose, xylose, and arabinose was observed and18.2 g/L lactic acid was obtained after 48 h fermentation. These results proved that B. coagulans NL01 was potentially well-suited for producing lactic acid from underutilized xylose-rich prehydrolysates.

  16. A novel pancoronavirus RT-PCR assay: frequent detection of human coronavirus NL63 in children hospitalized with respiratory tract infections in Belgium

    Directory of Open Access Journals (Sweden)

    Berkhout Ben

    2005-02-01

    Full Text Available Abstract Background Four human coronaviruses are currently known to infect the respiratory tract: human coronaviruses OC43 (HCoV-OC43 and 229E (HCoV-229E, SARS associated coronavirus (SARS-CoV and the recently identified human coronavirus NL63 (HCoV-NL63. In this study we explored the incidence of HCoV-NL63 infection in children diagnosed with respiratory tract infections in Belgium. Methods Samples from children hospitalized with respiratory diseases during the winter seasons of 2003 and 2004 were evaluated for the presence of HCoV-NL63 using a optimized pancoronavirus RT-PCR assay. Results Seven HCoV-NL63 positive samples were identified, six were collected during January/February 2003 and one at the end of February 2004. Conclusions Our results support the notation that HCoV-NL63 can cause serious respiratory symptoms in children. Sequence analysis of the S gene showed that our isolates could be classified into two subtypes corresponding to the two prototype HCoV-NL63 sequences isolated in The Netherlands in 1988 and 2003, indicating that these two subtypes may currently be cocirculating.

  17. Measuring illness beliefs in patients with lower extremity injuries: reliability and validity of the Dutch version of the Somatic Pre-Occupation and Coping questionnaire (SPOC-NL).

    Science.gov (United States)

    Reininga, Inge H F; Brouwer, Sandra; Dijkstra, Anita; Busse, Jason W; Ebrahim, Shanil; Wendt, Klaus W; El Moumni, Mostafa

    2015-02-01

    Positive coping strategies, illness perceptions and recovery expectations are associated with better clinical outcomes and earlier return to work after injuries. The Somatic Pre-Occupation and Coping (SPOC) questionnaire captures illness beliefs and coping towards recovery of physical function and return to work after surgical treatment of tibial shaft fractures. The aim of this study was to translate and culturally adapt the SPOC into Dutch (SPOC-NL) and evaluate its reliability and validity in patients with lower extremity injuries. The SPOC-NL contains four subscales: Somatic complaints, Coping, Energy, and Optimism. Patients treated for lower extremity injuries (N=106) completed the SPOC-NL, Short Form-36 and Short Musculoskeletal Function Assessment (SMFA-NL) questionnaire, and reported their current work status and self-perceived work ability. To assess test-retest reliability, 56 patients completed the SPOC-NL for a second time two weeks after the first administration of the SPOC-NL. We calculated Cronbach's Alpha, intraclass correlation coefficients (ICCs) and G coefficients to measure internal consistency and overall reliability, and used the Bland and Altman method to assess bias between test and retest SPOC-NL scores. To determine construct validity, we explored 16 a priori hypotheses regarding correlations between SPOC-NL scores and subscale scores and SF-36, SMFA-NL, work status and work ability. Internal consistency was good to excellent, with Cronbach's Alpha values ranging between 0.79 and 0.94 and G coefficients ranging between 0.77 and 0.95. Test-retest reliability was also good, since high ICCs (0.72-0.91) and G coefficients (0.82-0.94) were found. Construct validity of the SPOC-NL was good, as 75% of the predefined hypotheses were confirmed. Compared to participants who were on sick leave or receiving disability benefits, participants with a paid job had significantly higher scores on the total score and the subscales Somatic complaints and

  18. Validity and reliability of the Dutch version of the Copenhagen Hip And Groin Outcome Score (HAGOS-NL in patients with hip pathology.

    Directory of Open Access Journals (Sweden)

    Hilde Giezen

    Full Text Available The Copenhagen Hip And Groin Outcome Score (HAGOS was developed to assess disease-specific consequences in young to middle-aged, physically active hip and/or groin patients. The study aimed to determine validity and reliability of the Dutch version of the HAGOS (HAGOS-NL for middle-aged patients with hip complaints.To assess validity, 117 participants completed five questionnaires: HAGOS-NL, international Hip Outcome Tool (iHOT-12NL, Hip disability and Osteoarthritis Outcome Score (HOOS, RAND-36 Health Survey and Tegner activity scale. Structural validity was determined by conducting confirmatory factor analysis. Construct validity was analyzed by formulating predefined hypotheses regarding relationships between the HAGOS-NL and subscales of the iHOT-12NL, HOOS, RAND-36 and Tegner activity scale. The HAGOS-NL was filled out again by 67 patients to explore test-retest reliability. Reliability was assessed in terms of Cronbach's alpha, Intraclass Correlation Coefficient (ICC, Standard Error of Measurement (SEM and Minimal Detectable Change (MDC. The Bland and Altman method was used to explore absolute agreement.Factor analysis confirmed that the HAGOS-NL consists of six subscales. All hypotheses were confirmed, indicating good construct validity. Internal consistency was good, with Cronbach's alpha values ranging from 0.89 to 0.98. Test-retest reliability was considered good, with ICC values of 0.80 and higher. The SEM ranged from 6.6 to 12.3, and MDC at individual level from 18.3 to 34.1 and at group level from 2.3 to 4.4. Bland and Altman analyses showed no bias.The HAGOS-NL is a reliable and valid instrument for measuring pain, physical functioning and quality of life in middle-aged patients with hip complaints.

  19. The clinical learning environment and supervision instrument (CLES): validity and reliability of the Dutch version (CLES+NL).

    Science.gov (United States)

    De Witte, Nico; Labeau, Sonia; De Keyzer, Willem

    2011-05-01

    The clinical learning environment and supervision scale (CLES) is a valid and reliable tool that was developed to assess the quality of nursing students' clinical placements. To obtain a reliable and valid Dutch version of the CLES that is in line with the Flemish culture and educational context. Scale validation study on data provided by a cross-sectional survey. 190 wards in 31 institutions for healthcare in Flanders, Belgium. 768 student nurses enrolled in the 3 year bachelor programme at University College Ghent, Faculty of Healthcare Vesalius. Face and content validation was followed by data collection. Factor analysis was performed using varimax rotation. Subsequently, internal consistency reliability was tested on the total scale and its subdimensions using Cronbach's alpha. We gathered 768 questionnaires. Factor analysis revealed 5 subdimensions with an eigenvalue greater than 1, explaining 71.281% of the variance. The overall internal consistency and the consistency of the five subdimensions is high. Our data supports face, content and construct validity of the CLES+NL. The CLES+NL is a valid and reliable instrument that can be used to evaluate the quality of nursing wards as learning environments in Flanders. Copyright © 2010 Elsevier Ltd. All rights reserved.

  20. Diversity and Evolutionary Histories of Human Coronaviruses NL63 and 229E Associated with Acute Upper Respiratory Tract Symptoms in Kuala Lumpur, Malaysia.

    Science.gov (United States)

    Al-Khannaq, Maryam Nabiel; Ng, Kim Tien; Oong, Xiang Yong; Pang, Yong Kek; Takebe, Yutaka; Chook, Jack Bee; Hanafi, Nik Sherina; Kamarulzaman, Adeeba; Tee, Kok Keng

    2016-05-04

    The human alphacoronaviruses HCoV-NL63 and HCoV-229E are commonly associated with upper respiratory tract infections (URTI). Information on their molecular epidemiology and evolutionary dynamics in the tropical region of southeast Asia however is limited. Here, we analyzed the phylogenetic, temporal distribution, population history, and clinical manifestations among patients infected with HCoV-NL63 and HCoV-229E. Nasopharyngeal swabs were collected from 2,060 consenting adults presented with acute URTI symptoms in Kuala Lumpur, Malaysia, between 2012 and 2013. The presence of HCoV-NL63 and HCoV-229E was detected using multiplex polymerase chain reaction (PCR). The spike glycoprotein, nucleocapsid, and 1a genes were sequenced for phylogenetic reconstruction and Bayesian coalescent inference. A total of 68/2,060 (3.3%) subjects were positive for human alphacoronavirus; HCoV-NL63 and HCoV-229E were detected in 45 (2.2%) and 23 (1.1%) patients, respectively. A peak in the number of HCoV-NL63 infections was recorded between June and October 2012. Phylogenetic inference revealed that 62.8% of HCoV-NL63 infections belonged to genotype B, 37.2% was genotype C, while all HCoV-229E sequences were clustered within group 4. Molecular dating analysis indicated that the origin of HCoV-NL63 was dated to 1921, before it diverged into genotype A (1975), genotype B (1996), and genotype C (2003). The root of the HCoV-229E tree was dated to 1955, before it diverged into groups 1-4 between the 1970s and 1990s. The study described the seasonality, molecular diversity, and evolutionary dynamics of human alphacoronavirus infections in a tropical region. © The American Society of Tropical Medicine and Hygiene.

  1. Úvodník 2007/II/2

    Directory of Open Access Journals (Sweden)

    Jana Dlouhá

    2007-08-01

    Full Text Available Úvodník 2007/II/2 2007-09-06 08:59:20 Nové číslo Envigogiky srdečně zdraví své čtenáře. Tentokrát jsme se zaměřili na interdisciplinární téma. Ne všechny články se ho týkají – zdá se, že pro jejich pečlivé zpracování bylo málo času. My i naši autoři s údivem zjišťujeme, že napsat a posléze zpracovat text pro recenzovanou rubriku zabere spoustu času, samotné recenzní řízení je totiž záležitost časově náročná. Některé články se vracejí k přepracování, musíme znovu oslovit recenzenty, zda jsou s úpravami spokojeni, nebo dokonce zahájit nové kolečko posuzování a dalších úprav textu... Máme ale štěstí, připomínky bývají velmi užitečné, autoři jsou nakonec rádi, že mají rovnocenného partnera v dialogu, který někdy výrazně zlepšuje úroveň jejich práce. Příspěvek recenzentů ke konečné podobě článku se snažíme řádně ocenit – posudky se souhlasem všech zúčastněných zveřejňujeme (uvádíme je na konci textů. Jaké články tentokrát vydáváme, to si můžete podrobně prohlédnout v obsahu čísla – zde jsou i jejich krátké anotace. Takže můžeme jen stručně upozornit na nová témata či prvky, které nás příjemně překvapily. Polemický článek o zakladateli hlubinné ekologie Arne Naessovi píše Bohuslav Binka. K praxi vysokoškolského vzdělávání směřují Petr Šauer a Aleš Lisa – popisují „případy“ využití případových studií ve výuce. Wendy Drozenová zahajuje cyklus svých koláží a Rohan Wickramasinghe rozebírá ekologické prvky v různých náboženstvích na jeho rodné Srí Lance. Téma etiky, zdá se, přetrvalo (rozebírali jsme jej v minulém čísle a objevuje se v mnoha příspěvcích. Katka Jančaříková píše o úctě k životu a školní praxi vycházející z rámcových vzdělávacích programů; František Murgaš o kvalitě života a indikátorech, které by ji mohly m

  2. Genomic analysis of a xylose operon and characterization of novel xylose isomerase and xylulokinase from Bacillus coagulans NL01.

    Science.gov (United States)

    Zheng, Zhaojuan; Lin, Xi; Jiang, Ting; Ye, Weihua; Ouyang, Jia

    2016-08-01

    To investigate the xylose operon and properties of xylose isomerase and xylulokinase in Bacillus coagulans that can effectively ferment xylose to lactic acid. The xylose operon is widely present in B. coagulans. It is composed of four putative ORFs. Novel xylA and xylB from B. coagulans NL01 were cloned and expressed in Escherichia coli. Sequence of xylose isomerase was more conserved than that of xylulokinase. Both the enzymes exhibited maximum activities at pH 7-8 but with a high temperature maximum of 80-85 °C, divalent metal ion was prerequisite for their activation. Xylose isomerase and xylulokinase were most effectively activated by Ni(2+) and Co(2+), respectively. Genomic analysis of xylose operon has contributed to understanding xylose metabolism in B. coagulans and the novel xylose isomerase and xylulokinase might provide new alternatives for metabolic engineering of other strains to improve their fermentation performance on xylose.

  3. Fen Bilgisi Öğretmen Adaylarının Kimya Bilgilerini Günlük Hayatla İlişkilendirebilme Düzeyleri

    OpenAIRE

    Yadigaroğlu, Yrd. Doç. Dr. Mustafa; DEMİRCİOĞLU, Doç. Dr. Gökhan; DEMİRCİOĞLU, Doç. Dr. Hülya

    2017-01-01

    Fen eğitiminin temel amaçlarındanbiri, öğrencilerin fen okur-yazarı olmalarını sağlayarak onları günlükyaşantılarında karşılaştıkları fen olaylarına anlam vermelerine yardımcıolmaktır. Günlük hayatla ya da bağlamı ile ilişkilendirilmeyen bilgi öğrencininzihninde her zaman eksik olacaktır. Bunun gerçekleştirilmesinde fen dersleriiçerisinde yer alan kimya önemli bir yere sahiptir. Bu düşünceden hareketleçalışmada, fen bilgisi öğretmen adaylarının kimya bilgilerini günlük hayatlailişkilendirebil...

  4. Ras Labs-CASIS-ISS NL experiment for synthetic muscle returned to Earth: resistance to ionizing radiation

    Science.gov (United States)

    Rasmussen, Lenore; Albers, Leila N.; Rodriguez, Simone; Gentile, Charles; Meixler, Lewis D.; Ascione, George; Hitchner, Robert; Taylor, James; Hoffman, Dan; Cylinder, David; Gaza, Ramona; Moy, Leon; Mark, Patrick S.; Prillaman, Daniel L.; Nodarse, Robert; Menegus, Michael J.; Ratto, Jo Ann; Thellen, Christopher T.; Froio, Danielle; Valenza, Logan; Poirier, Catherine; Sinkler, Charles; Corl, Dylan; Hablani, Surbhi; Fuerst, Tyler; Gallucci, Sergio; Blocher, Whitney; Liffland, Stephanie

    2017-04-01

    In anticipation of deep space travel, new materials are being explored to assist and relieve humans in dangerous environments, such as high radiation, extreme temperature, and extreme pressure. Ras Labs Synthetic Muscle™ - electroactive polymers (EAPs) that contract and expand at low voltages - which mimic the unique gentle-yet-strong nature of human tissue, is a potential asset to manned space travel through protective gear and human assist robotics and for unmanned space exploration through deep space. Gen 3 Synthetic Muscle™ was proven to be resistant to extreme temperatures, and there were indications that these materials would also be radiation resistant. The purpose of the Ras Labs-CASIS-ISS Experiment was to test the radiation resistivity of the third and fourth generation of these EAPs, as well as to make them even more radiation resistant. On Earth, exposure of the Generation 3 and Generation 4 EAPs to a Cs-137 radiation source for 47.8 hours with a total dose of 305.931 kRad of gamma radiation was performed at the US Department of Energy's Princeton Plasma Physics Laboratory (PPPL) at Princeton University, followed by pH, peroxide, Shore Hardness durometer, and electroactivity testing to determine the inherent radiation resistivity of these contractile EAPs, and to determine whether the EAPs could be made even more radiation resistant through the application of appropriate additives and coatings. The on Earth preliminary tests determined that selected Ras Labs EAPs were not only inherently radiation resistant, but with the appropriate coatings and additives, could be made even more radiation resistant. G-force testing to over 10 G's was performed at US Army's ARDEC Labs, with excellent results, in preparation for space flight to the International Space Station National Laboratory (ISS-NL). Selected samples of Generation 3 and Generation 4 Synthetic Muscle™, with various additives and coatings, were launched to the ISS-NL on April 14, 2015 on the

  5. Characterization of an L-arabinose isomerase from Bacillus coagulans NL01 and its application for D-tagatose production.

    Science.gov (United States)

    Mei, Wending; Wang, Lu; Zang, Ying; Zheng, Zhaojuan; Ouyang, Jia

    2016-06-30

    L-arabinose isomerase (AI) is a crucial catalyst for the biotransformation of D-galactose to D-tagatose. In previous reports, AIs from thermophilic bacterial strains had been wildly researched, but the browning reaction and by-products formed at high temperatures restricted their applications. By contrast, AIs from mesophilic Bacillus strains have some different features including lower optimal temperatures and lower requirements of metallic cofactors. These characters will be beneficial to the development of a more energy-efficient and safer production process. However, the relevant data about the kinetics and reaction properties of Bacillus AIs in D-tagatose production are still insufficient. Thus, in order to support further applications of these AIs, a comprehensive characterization of a Bacillus AI is needed. The coding gene (1422 bp) of Bacillus coagulans NL01 AI (BCAI) was cloned and overexpressed in the Escherichia coli BL21 (DE3) strain. The enzymatic property test showed that the optimal temperature and pH of BCAI were 60 °C and 7.5 respectively. The raw purified BCAI originally showed high activity in absence of outsourcing metallic ions and its thermostability did not change in a low concentration (0.5 mM) of Mn(2+) at temperatures from 70 °C to 90 °C. Besides these, the catalytic efficiencies (k cat/K m) for L-arabinose and D-galactose were 8.7 mM(-1) min(-1) and 1.0 mM(-1) min(-1) respectively. Under optimal conditions, the recombinant E. coli cell containing BCAI could convert 150 g L(-1) and 250 g L(-1) D-galactose to D-tagatose with attractive conversion rates of 32 % (32 h) and 27 % (48 h). In this study, a novel AI from B. coagulans NL01was cloned, purified and characterized. Compared with other reported AIs, this AI could retain high proportions of activity at a broader range of temperatures and was less dependent on metallic cofactors such as Mn(2+). Its substrate specificity was understood deeply by carrying out molecular

  6. Bouwstenen voor alarmberichten in het kader van NL-Alert : Rapportage over de ontwikkeling van berichtgeving voor burgeralarmering via cell broadcast

    NARCIS (Netherlands)

    Jagtman, H.M.; Sillem, S.; Ale, B.J.M.

    2011-01-01

    In dit rapport zijn de resultaten beschreven van de opdracht van het Ministerie van Veiligheid en Justitie aan de TU Delft om een aanzet te leveren tot een berichtendatabase ten behoeve van de implementatie van NL-Alert. In het kader van deze opdracht zijn opgesteld en onderzocht: • Een

  7. Reliability of the modified Paediatric Evaluation of Disability Inventory, Dutch version (PEDI-NL) for children with cerebral palsy and cerebral visual impairment.

    Science.gov (United States)

    Salavati, M; Waninge, A; Rameckers, E A A; de Blécourt, A C E; Krijnen, W P; Steenbergen, B; van der Schans, C P

    2015-02-01

    The aims of this study were to adapt the Paediatric Evaluation of Disability Inventory, Dutch version (PEDI-NL) for children with cerebral visual impairment (CVI) and cerebral palsy (CP) and determine test-retest and inter-respondent reliability. The Delphi method was used to gain consensus among twenty-one health experts familiar with CVI. Test-retest and inter-respondent reliability were assessed for parents and caregivers of 75 children (aged 50-144 months) with CP and CVI. The percentage identical scores of item scores were computed, as well as the interclass coefficients (ICC) and Cronbach's alphas of scale scores over the domains self-care, mobility, and social function. All experts agreed on the adaptation of the PEDI-NL for children with CVI. On item score, for the Functional Skills scale, mean percentage identical scores variations for test-retest reliability were 73-79 with Caregiver Assistance scale 73-81, and for inter-respondent reliability 21-76 with Caregiver Assistance scale 40-43. For all scales over all domains ICCs exceeded 0.87. For the domains self-care, mobility, and social function, the Functional Skills scale and the Caregiver Assistance scale have Cronbach's alpha above 0.88. The adapted PEDI-NL for children with CP and CVI is reliable and comparable to the original PEDI-NL. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. Reliability of the modified Paediatric Evaluation of Disability Inventory, Dutch version (PEDI-NL) for children with cerebral palsy and cerebral visual impairment

    NARCIS (Netherlands)

    Salavati, M.; Waninge, A.; Rameckers, E. A. A.; de Blecourt, A. C. E.; Krijnen, W. P.; Steenbergen, B.; van der Schans, C. P.

    Purpose: The aims of this study were to adapt the Paediatric Evaluation of Disability Inventory, Dutch version (PEDI-NL) for children with cerebral visual impairment (CVI) and cerebral palsy (CP) and determine test-retest and inter-respondent reliability. Method: The Delphi method was used to gain

  9. An adenylyl cyclase like-9 gene (NlAC9 influences growth and fecundity in the brown planthopper, Nilaparvata lugens (Stål (Hemiptera: Delphacidae.

    Directory of Open Access Journals (Sweden)

    LinQuan Ge

    Full Text Available The cAMP/PKA intracellular signaling pathway is launched by adenylyl cyclase (AC conversion of adenosine triphosphate (ATP to 3', 5'-cyclic AMP (cAMP and cAMP-dependent activation of PKA. Although this pathway is very well known in insect physiology, there is little to no information on it in some very small pest insects, such as the brown planthopper (BPH, Nilaparvata lugens Stål. BPH is a destructive pest responsible for tremendous crop losses in rice cropping systems. We are investigating the potentials of novel pest management technologies from RNA interference perspective. Based on analysis of transcriptomic data, the BPH AC like-9 gene (NlAC9 was up-regulated in post-mating females, which led us to pose the hypothesis that NlAC9 is a target gene that would lead to reduced BPH fitness and populations. Targeting NlAC9 led to substantially decreased soluble ovarian protein content, yeast-like symbiont abundance, and vitellogenin gene expression, accompanied with stunted ovarian development and body size. Eggs laid were decreased and oviposition period shortened. Taken together, our findings indicated that NlAC9 exerted pronounced effects on female fecundity, growth and longevity, which strongly supports our hypothesis.

  10. An adenylyl cyclase like-9 gene (NlAC9) influences growth and fecundity in the brown planthopper, Nilaparvata lugens (Stål) (Hemiptera: Delphacidae).

    Science.gov (United States)

    Ge, LinQuan; Gu, HaoTian; Huang, Bo; Song, Qisheng; Stanley, David; Liu, Fang; Yang, Guo-Qing; Wu, Jin-Cai

    2017-01-01

    The cAMP/PKA intracellular signaling pathway is launched by adenylyl cyclase (AC) conversion of adenosine triphosphate (ATP) to 3', 5'-cyclic AMP (cAMP) and cAMP-dependent activation of PKA. Although this pathway is very well known in insect physiology, there is little to no information on it in some very small pest insects, such as the brown planthopper (BPH), Nilaparvata lugens Stål. BPH is a destructive pest responsible for tremendous crop losses in rice cropping systems. We are investigating the potentials of novel pest management technologies from RNA interference perspective. Based on analysis of transcriptomic data, the BPH AC like-9 gene (NlAC9) was up-regulated in post-mating females, which led us to pose the hypothesis that NlAC9 is a target gene that would lead to reduced BPH fitness and populations. Targeting NlAC9 led to substantially decreased soluble ovarian protein content, yeast-like symbiont abundance, and vitellogenin gene expression, accompanied with stunted ovarian development and body size. Eggs laid were decreased and oviposition period shortened. Taken together, our findings indicated that NlAC9 exerted pronounced effects on female fecundity, growth and longevity, which strongly supports our hypothesis.

  11. Degree of urbanization and mammographic density in Dutch breast cancer screening participants: results from the EPIC-NL cohort.

    Science.gov (United States)

    Emaus, Marleen J; Bakker, Marije F; Beelen, Rob M J; Veldhuis, Wouter B; Peeters, Petra H M; van Gils, Carla H

    2014-12-01

    It has been observed that women living in urban areas have a higher mammographic density (MD) compared to women living in rural areas. This association might be explained by regional differences in reproductive and lifestyle factors or perhaps by variation in exposure to ambient air pollution as air pollution particles have been described to show estrogenic activity. We investigated the association between degree of urbanization and MD, and aimed to unravel the underlying etiology. 2,543 EPIC-NL participants were studied, and general linear models were used. Urbanization was categorized into five categories according to the number of addresses/km(2). Information on reproductive and lifestyle factors was obtained from the recruitment questionnaire. Air pollution exposure was estimated using land-use regression models. MD was expressed as percent density (PD) and dense area (DA), and was quantified using Cumulus. Women living in extremely urbanized areas had a higher PD (21.4%, 95% confidence interval (CI) 20.5-22.3%) compared to women living in not urbanized areas (16.1, 95% CI 14.5-17.8%, P trend air pollution (adjusted PDextremely_urbanized = 22.1%, 95% CI 18.0-26.5% versus adjusted PDnot_urbanized = 16.9%, 95% CI 13.0-21.2, P trend urbanization is associated with MD. The association could not be explained by differences in reproductive and lifestyle factors or by variation in air pollution exposure.

  12. Effects of Inhibitors on the Transcriptional Profiling of Gluconobater oxydans NL71 Genes after Biooxidation of Xylose into Xylonate

    Directory of Open Access Journals (Sweden)

    Yong Xu

    2017-04-01

    Full Text Available D-Xylonic acid belongs to the top 30 biomass-based platform chemicals and represents a promising application of xylose. Until today, Gluconobacter oxydans NL71 is the most efficient microbe capable of fermenting xylose into xylonate. However, its growth is seriously inhibited when concentrated lignocellulosic hydrolysates are used as substrates due to the presence of various degraded compounds formed during biomass pretreatment. Three critical lignocellulosic inhibitors were thereby identified, i.e., formic acid, furfural, and 4-hydroxybenzaldehyde. As microbe fermentation is mostly regulated at the genome level, four groups of cell transcriptomes were obtained for a comparative investigation by RNA sequencing of a control sample with samples treated separately with the above-mentioned inhibitors. The digital gene expression profiles screened 572, 714 genes, and 408 DEGs was obtained by the comparisons among four transcriptomes. A number of genes related to the different functional groups showed characteristic expression patterns induced by three inhibitors, in which 19 genes were further tested and confirmed by qRT-PCR. We extrapolated many differentially expressed genes that could explain the cellular responses to the inhibitory effects. We provide results that enable the scientific community to better define the molecular processes involved in the microbes' responses to lignocellulosic inhibitors during the cellular biooxidation of xylose into xylonic acid.

  13. HowNutsAreTheDutch (HoeGekIsNL): A crowdsourcing study of mental symptoms and strengths.

    Science.gov (United States)

    Krieke, Lian Van Der; Jeronimus, Bertus F; Blaauw, Frank J; Wanders, Rob B K; Emerencia, Ando C; Schenk, Hendrika M; Vos, Stijn De; Snippe, Evelien; Wichers, Marieke; Wigman, Johanna T W; Bos, Elisabeth H; Wardenaar, Klaas J; Jonge, Peter De

    2016-06-01

    HowNutsAreTheDutch (Dutch: HoeGekIsNL) is a national crowdsourcing study designed to investigate multiple continuous mental health dimensions in a sample from the general population (n = 12,503). Its main objective is to create an empirically based representation of mental strengths and vulnerabilities, accounting for (i) dimensionality and heterogeneity, (ii) interactivity between symptoms and strengths, and (iii) intra-individual variability. To do so, HowNutsAreTheDutch (HND) makes use of an internet platform that allows participants to (a) compare themselves to other participants via cross-sectional questionnaires and (b) to monitor themselves three times a day for 30 days with an intensive longitudinal diary study via their smartphone. These data enable for personalized feedback to participants, a study of profiles of mental strengths and weaknesses, and zooming into the fine-grained level of dynamic relationships between variables over time. Measuring both psychiatric symptomatology and mental strengths and resources enables for an investigation of their interactions, which may underlie the wide variety of observed mental states in the population. The present paper describes the applied methods and technology, and presents the sample characteristics. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

  14. Roles of NlAKTIP in the Growth and Eclosion of the Rice Brown Planthopper, Nilaparvata lugens Stål, as Revealed by RNA Interference

    Directory of Open Access Journals (Sweden)

    Peiying Hao

    2015-09-01

    Full Text Available AKT-interacting protein (AKTIP interacts with serine/threonine protein kinase B (PKB/AKT. AKTIP modulates AKT’s activity by enhancing the phosphorylation of the regulatory site and plays a crucial role in multiple biological processes. In this study, the full length cDNA of NlAKTIP, a novel AKTIP gene in the brown planthopper (BPH Nilaparvata lugens, was cloned. The reverse transcription quantitive PCR (RT-qPCR results showed that the NlAKTIP gene was strongly expressed in gravid female adults, but was relatively weakly expressed in nymphs and male adult BPH. In female BPH, treatment with dsAKTIP resulted in the efficient silencing of NlAKTIP, leading to a significant reduction of mRNA levels, about 50% of those of the untreated control group at day 7 of the study. BPH fed with dsAKTIP had reduced growth with lower body weights and smaller sizes, and the body weight of BPH treated with dsAKTIP at day 7 decreased to about 30% of that of the untreated control. Treatment of dsAKTIP significantly delayed the eclosion for over 7 days relative to the control group and restricted ovarian development to Grade I (transparent stage, whereas the controls developed to Grade IV (matured stage. These results indicated that NlAKTIP is crucial to the growth and development of female BPH. This study provided a valuable clue of a potential target NlAKTIP for inhibiting the BPH, and also provided a new point of view on the interaction between BPH and resistant rice.

  15. NL Kids online

    NARCIS (Netherlands)

    Jos de Haan

    2010-01-01

    In Nederland, maar ook elders, verkennen jongeren intensief de mogelijkheden van internet. Deze verkenning begint overal op steeds jongere leeftijd. Jongeren krijgen te maken met zowel de positieve als de negatieve kanten van internet. Dit rapport bestudeert de aangeboden kansen en risico's van

  16. Effects of Long-Term Developmental Patterns of Adiposity on Levels of C-Reactive Protein and Fibrinogen among North-American Men and Women: The Spokane Heart Study

    Directory of Open Access Journals (Sweden)

    Trynke Hoekstra

    2014-06-01

    Full Text Available This study examined the heterogeneity in BMI development by identifying distinct developmental trajectories. These trajectories were further investigated by relating them to markers of low-grade inflammation later in life. Data from approximately 400 healthy volunteers participating in the Spokane Heart Study were collected in 2-year intervals, and four waves of data were available for the current analyses. Body weight was measured by BMI and low-grade inflammation by high-sensitivity C-reactive protein (CRP and fibrinogen. Up to date statistical techniques, i.e. latent class growth models, were used to analyse heterogeneity in body weight, and linear regressions were run to analyse possible associations between trajectories of body weight and CRP/fibrinogen levels. Six trajectories were identified (three stable, two increasing, and one decreasing which differed significantly on CRP/fibrinogen levels, highlighting the importance of weight trajectories. The differences were only partly explained by variations in lifestyle habits.

  17. Selected trace-element and synthetic-organic compound data for streambed sediment from the Clark Fork-Pend Oreille and Spokane River basins, Montana, Idaho, and Washington, 1998

    Science.gov (United States)

    Beckwith, Michael A.

    2002-01-01

    Streambed-sediment samples were collected at 22 sites during the summer of 1998 as part of the U.S. Geological Survey National Water-Quality Assessment Program. Sampling sites in the Clark Fork-Pend Oreille and Spokane River basins represented a wide range of environmental conditions including pristine mountain streams and large rivers affected by mining-related and urban activities. Samples were analyzed for 45 inorganic major and trace elements, 109 syn­thetic organic compounds, and carbon. This report pre­sents the selected results of streambed-sediment sampling from the Clark Fork-Pend Oreille and Spo­kane River basins in Montana, Idaho, and Washington.

  18. Çoruh Havza’sındaki Günlük Maksimum Yağış Serilerinin Trend Analizi

    OpenAIRE

    TOSUNOĞLU, Fatih

    2017-01-01

    Bu çalışmada, yıllık, mevsimlik ve aylık üç zaman dilimdeki günlük maksimum yağışların trendleriMann-Kendall (MK), modifye edilmiş Mann-Kendall (mMK), Theil-Sen (TH) ve Mann-Kendall Sıra Korelasyon(MKSK) testleri kullanılarak araştırılmıştır. Bu testler, Çoruh havzasında bulunan 5 adet istasyonun günlükmaksimum yağış verilerine uygulanmıştır. MK ve mMK testleri trendlerin anlamlılığını belirlemede, TH testitrendin büyüklüğünü hesaplamada ve MKSK testi ise ele alınan verilerdeki anlamlı trendl...

  19. Hyperfine structure of the metastable p-barHe+ atom revealed by a laser-induced (n,l) = (37,35) → (38,34) transition

    International Nuclear Information System (INIS)

    Widmann, E.; Eades, J.; Yamazaki, T.

    1996-11-01

    A precise scan of the previously discovered laser-induced transition (n,l) = (37,35) → (38,34) in p-barHe + revealed a doublet structure with a separation of Δν HF = 1.70 ± 0.05 GHz. This new type of 'hyperfine' splitting is ascribed to the interaction of the antiproton orbital angular momentum and the electron spin. (author)

  20. Enderunlu Vâsıf’ın “Gönlümdeki” Redifli Gazelinde Tasavvufî Söylem* Sufistic Discourse in “Gönlümdeki” Rhymed Gazelle by Enderunlu Vasıf Named

    Directory of Open Access Journals (Sweden)

    Ahmet DOĞAN

    2012-09-01

    Full Text Available In all sources he is mentioned, Enderunlu Vasıf, one of the last period figures of Divan literature, is defined as a poet followed in wake that Nedim marked a century ago. Enderunlu Vasıf is regarded as “a simple imitation of Nedim” and said to be mundaneness when he digresses the grace of Nedim-like discourse. In addition, he is said to have presented a hopeless, debauched, bohemian personality in his poems. But Enderunlu Vasıf, is evaluated as “a man at a moderate level who trained with the former discipline” and his work as seen in “above all certificate of disintegration to enjoy”. From time totime we witness that he shelters the peaceful climate of Sufism by expressing the spiritual alienation caused by the sociocultural changes of his era in Sufistic discourse. Enderunlu Vasıf's the attitudes of cynical, reckless and unbuttoned is as well as is seen as one who is equally caring of the life and art. For this reason, he appears as two different mood. This situation creates the impression that the poems were written by two different poets. It is possible to observe this ambivalent structure, seen both in feelings and poems of Enderunlu Vasıf, in “gönlümdeki” rhymed gazelle more distinctly. In the poem, virtual and esoteric “I” perception is revealed; and contrary to expectations, by addressing “esoteric I”, gazelle is presented to attention in sufistic profundity. Divan edebiyatının son dönem şahsiyetlerinden olan Enderunlu Vâsıf, isminin geçtiği hemen bütün kaynaklarda, yüz yıl önce Nedîm’in açmış olduğu çığırda yürüyen bir şair olarak tanımlanır. Kendisinden “Nedim’in basit bir kopyası” olarak bahsedilen ve kimi zaman “Nedîmâne” söyleyişteki zarafetten uzaklaşarak bayağılığa düştüğü kaydedilen Enderunlu Vâsıf’ın, şiirlerinde daha çok umursamaz, zevke ve eğlenceye düşkün, hayatı ciddiye almayan bir kişilik sergilediği söylenir. Ancak

  1. Technical principles underlying limit values for release of substances for the percolation test TS3: comparison DE and NL

    Energy Technology Data Exchange (ETDEWEB)

    Van Zomeren, A.; Dijkstra, J.J. [ECN Environment and Energy Engineering, Petten (Netherlands); Susset, B. [Consulting Office SiWaP (Germany)

    2013-10-15

    Within CEN TC 351 WG 1, standardized, horizontal test methods are developed to assess the release (leaching) of dangerous substances from construction as defined in ER3 of the CPD. For granular materials TS 3, a horizontal up-flow percolation test, was further developed by CEN TC 351 WG1 and will enter the validation phase in 2013. In CEN TC 351 WG1, there are still discussions regarding the sample preparation and some test conditions. Currently, two options for sample preparation and test conditions are specified. Controversy between DE and NL regarding sample preparation and test conditions and the need for two separate options in the TS 3 percolation test are possibly for a part caused by different approaches for risk assessment in the Netherlands and in Germany and the resulting regulatory concepts. One important reason for this is, that in soil and groundwater regulations the test method and the impact assessment method are systematically linked together but the impact assessment methods and lab methods in both countries are different. The discussions in CEN TC 351 WG 1 show that there is a need to have a better mutual understanding of the relation between test method and impact assessment on the one hand and a clear overview of differences in impact assessment approaches of each country on the other hand. The aim of this project is to explain and compare the assumptions, boundary conditions and conventions of the impact assessment approach that are implemented in the upcoming German Recycling Degree and in the Soil Quality Degree of the Netherlands. Ultimately, a better understanding of the impact assessment approaches provides a basis for further discussion in WG1 to agree on only one option for the percolation test conditions. The following report is prepared by the contractors of Germany and Netherlands together to compare the two country-specific concepts. This report summarizes and explains the presentation given on the 25th of April at TC 351 WG1 in

  2. Depleted and enriched uranium exposure quantified in former factory workers and local residents of NL Industries, Colonie, NY USA

    International Nuclear Information System (INIS)

    Arnason, John G.; Pellegri, Christine N.; Moore, June L.; Lewis-Michl, Elizabeth L.; Parsons, Patrick J.

    2016-01-01

    Background: Between 1958 and 1982, NL Industries manufactured components of enriched (EU) and depleted uranium (DU) at a factory in Colonie NY, USA. More than 5 metric tons of DU was deposited as microscopic DU oxide particles on the plant site and surrounding residential community. A prior study involving a small number of individuals (n=23) indicated some residents were exposed to DU and former workers to both DU and EU, most probably through inhalation of aerosol particles. Objectives: Our aim was to measure total uranium [U] and the uranium isotope ratios: 234 U/ 238 U; 235 U/ 238 U; and 236 U/ 238 U, in the urine of a cohort of former workers and nearby residents of the NLI factory, to characterize individual exposure to natural uranium (NU), DU, and EU more than 3 decades after production ceased. Methods: We conducted a biomonitoring study in a larger cohort of 32 former workers and 99 residents, who may have been exposed during its period of operation, by measuring Total U, NU, DU, and EU in urine using Sector Field Inductively Coupled Plasma - Mass Spectrometry (SF-ICP-MS). Results: Among workers, 84% were exposed to DU, 9% to EU and DU, and 6% to natural uranium (NU) only. For those exposed to DU, urinary isotopic and [U] compositions result from binary mixing of NU and the DU plant feedstock. Among residents, 8% show evidence of DU exposure, whereas none shows evidence of EU exposure. For residents, the [U] geometric mean is significantly below the value reported for NHANES. There is no significant difference in [U] between exposed and unexposed residents, suggesting that [U] alone is not a reliable indicator of exposure to DU in this group. Conclusions: Ninety four percent of workers tested showed evidence of exposure to DU, EU or both, and were still excreting DU and EU decades after leaving the workforce. The study demonstrates the advantage of measuring multiple isotopic ratios (e.g., 236 U/ 238 U and 235 U/ 238 U) over a single ratio ( 235 U/ 238 U

  3. Dr. Hans Chang, Director, Physics Research Committee, Stichting voor Fundamenteel Onderzoek der Materie (FOM), Dr. Joris Van Enst, Head of Science Policy Division, Ministry of Education, Culture and S cience, Dr. Jan Bezemer, NL Delegate CERN, Netherlands

    CERN Multimedia

    Patrice Loiez

    1999-01-01

    Dr. Hans Chang, Director, Physics Research Committee, Stichting voor Fundamenteel Onderzoek der Materie (FOM), Dr. Joris Van Enst, Head of Science Policy Division, Ministry of Education, Culture and S cience, Dr. Jan Bezemer, NL Delegate CERN, Netherlands

  4. Neutralization of X4- and R5-tropic HIV-1 NL4-3 variants by HOCl-modified serum albumins

    Directory of Open Access Journals (Sweden)

    Schwalbe Birco

    2010-06-01

    Full Text Available Abstract Background Myeloperoxidase (MPO, an important element of the microbicidal activity of neutrophils, generates hypochlorous acid (HOCl from H2O2 and chloride, which is released into body fluids. Besides its direct microbicidal activity, HOCl can react with amino acid residues and HOCl-modified proteins can be detected in vivo. Findings This report is based on binding studies of HOCl-modified serum albumins to HIV-1 gp120 and three different neutralization assays using infectious virus. The binding studies were carried out by surface plasmon resonance spectroscopy and by standard ELISA techniques. Virus neutralization assays were carried out using HIV-1 NL4-3 virus and recombinant strains with CXCR4 and CCR5 coreceptor usage. Viral infection was monitored by a standard p24 or X-gal staining assay. Our data demonstrate that HOCl-modified mouse-, bovine- and human serum albumins all bind to the HIV-1 NL4-3 gp120 (LAV glycoprotein in contrast to non-modified albumin. Binding of HOCl-modified albumin to gp120 correlated to the blockade of CD4 as well as that of V3 loop specific monoclonal antibody binding. In neutralization experiments, HOCl-modified serum albumins inhibited replication and syncytium formation of the X4- and R5-tropic NL4-3 isolates in a dose dependent manner. Conclusions Our data indicate that HOCl-modified serum albumin veils the binding site for CD4 and the V3 loop on gp120. Such masking of the viral gp120/gp41 envelope complex might be a simple but promising strategy to inactivate HIV-1 and therefore prevent infection when HOCl-modified serum albumin is applied, for example, as a topical microbicide.

  5. Kur’an’a Göre Üstünlük Duygusunun Düşünce ve Davranışlara Etkileri

    Directory of Open Access Journals (Sweden)

    Harun Savut

    2015-06-01

    Full Text Available Üstünlük duygusu insanın tüm davranışlarını etkisi altına alan, düşünce ve davranışlarda sapmalara sebep olan bir tavırdır. Doğruyu kendisini merkeze koyarak değerlendiren insanın tüm kutsalı yine kendisi olur. Şayet çevredekiler bu kutsalı onaylarsa kabul edilir ve değer görürler. Aksinin söz konusu olduğu durumlarda ise karşı durulması gereken düşman şeklinde algılanırlar. Bu ise akli melekelerin önünde set oluşturan, doğru düşünmeyi negatif yönde etkileyen, bu sebeple de yanlışları tetikleyen bir durumdur. Bunun neticesinde hakkın kabulü zorlaşır, hatta imkansız bir hal alır. İnsanı kendi algısı ile çelişen gerçekleri, doğruları inkara sürükler. Benlik kaynaklı bu savrulma küfür ve şirkin kapılarını açar. Bu makalede üstünlük hissinin yol açtığı algı ve düşünme hatalarıyla tebarüz eden kişilerin düşüncelerinde ortaya çıkan savrulmalar, yanılsamalar analiz edilmiştir. Üstünlük algısının gerekçelendirilmesinde kişi veya toplumun sahip olduğu imkanların rolü değerlendirilmiştir. Üstünlük hissinin neden olduğu tahammülsüzlük ve algı kapanması üzerinde durulmuştur.

  6. Mechanical Design and Analysis of LCLS II 2 K Cold Box

    Science.gov (United States)

    Yang, S.; Dixon, K.; Laverdure, N.; Rath, D.; Bevins, M.; Bai, H.; Kaminski, S.; Ravindranath, V.

    2017-12-01

    The mechanical design and analysis of the LCLS II 2 K cold box are presented. Its feature and functionality are discussed. ASME B31.3 was used to design its internal piping, and compliance of the piping code was ensured through flexibility analysis. The 2 K cold box was analyzed using ANSYS 17.2; the requirements of the applicable codes—ASME Section VIII Division 2 and ASCE 7-10—were satisfied. Seismic load was explicitly considered in both analyses.

  7. Clinical validation of three short forms of the Dutch Wechsler Memory Scale-Fourth Edition (WMS-IV-NL) in a mixed clinical sample.

    Science.gov (United States)

    Bouman, Zita; Hendriks, Marc P H; Van Der Veld, William M; Aldenkamp, Albert P; Kessels, Roy P C

    2016-06-01

    The reliability and validity of three short forms of the Dutch version of the Wechsler Memory Scale-Fourth Edition (WMS-IV-NL) were evaluated in a mixed clinical sample of 235 patients. The short forms were based on the WMS-IV Flexible Approach, that is, a 3-subtest combination (Older Adult Battery for Adults) and two 2-subtest combinations (Logical Memory and Visual Reproduction and Logical Memory and Designs), which can be used to estimate the Immediate, Delayed, Auditory and Visual Memory Indices. All short forms showed good reliability coefficients. As expected, for adults (16-69 years old) the 3-subtest short form was consistently more accurate (predictive accuracy ranged from 73% to 100%) than both 2-subtest short forms (range = 61%-80%). Furthermore, for older adults (65-90 years old), the predictive accuracy of the 2-subtest short form ranged from 75% to 100%. These results suggest that caution is warranted when using the WMS-IV-NL Flexible Approach short forms to estimate all four indices. © The Author(s) 2015.

  8. Synthesis and blue electroluminescent properties of zinc (II) [2-(2-hydroxyphenyl)benzoxazole

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Won Sam [Department of Chemistry and BPRC, Inje University, Gimhae 621-749 (Korea, Republic of); You, Jung Min [Department of Chemistry and BPRC, Inje University, Gimhae 621-749 (Korea, Republic of); Lee, Burm-Jong [Department of Chemistry and BPRC, Inje University, Gimhae 621-749 (Korea, Republic of)]. E-mail: chemlbj@inje.ac.kr; Jang, Yoon-Ki [Department of Electrical Engineering, Dong-A University, Busan 604-714 (Korea, Republic of); Kim, Dong-Eun [Department of Electrical Engineering, Dong-A University, Busan 604-714 (Korea, Republic of); Kwon, Young-Soo [Department of Electrical Engineering, Dong-A University, Busan 604-714 (Korea, Republic of)

    2007-04-23

    This study reports on the properties of organic light-emitting diodes (OLEDs) with zinc (II) [2-(2-hydroxyphenyl)benzoxazole] as a hole-blocking layer. OLEDs devices are prepared in a conventional OLEDs structure (i.e., anode/HTL/EL/HBL/cathode and anode/HTL/HBL/EL/cathode). The luminescence efficiencies and the turn-on voltage are significantly affected by the existence of the hole-blocking layer. This is attributed to an excellent hole-blocking property, which is in turn due to the high HOMO energy level (6.5 eV). The device showed luminous efficiency 2.46 lm/W at 5 V. The maximum luminance of about 10,000 cd/m{sup 2} is obtained, and the turn-on voltage (2.5 V) is affected by the existence of the hole-blocking layer.

  9. Aksesuar Mental Foramen: Konik Işınlı Bilgisayarlı Tomografi Bulguları-Accessory Mental Foramen: Findings of cone-beam computed tomography

    OpenAIRE

    Sinanoğlu, Alper; Coşkunses, Fatih; Kan, Bahadır; Altan, Ayşe

    2014-01-01

    Aksesuar mental foramen (AMF), MF bölgesinde, MF’in birden fazla olması durumunda asıl foramenin dışındaki diğer foramenler olarak tanımlanmıştır. AMF’in lokalizasyon ve sayı varyasyonlarının ırk ve etnik yapıya göre farklılık gösterdiği rapor edilmiştir. Bu anatomik varyasyonun değerlendirilmesinde konik ışınlı bilgisayarlı tomografi kullanımı, ilgili alanın 3 boyutlu rekonstrüksiyonlarına ve kesitsel olarak değerlendirilmesine olanak sağlamaktadır. Bu çalışmada 23 yaşındaki kadın hastada te...

  10. Aksesuar mental foramenin konik-ışınlı bilgisayarlı tomografi ile görüntülenmesi: iki olgu bildirimi

    OpenAIRE

    Gümüşok, Mustafa; Zafersoy Akarslan, Zühre; Üçok, Özlem

    2015-01-01

    TANITIM: Mental foramen mandibulanın önemli anatomik yapılarındandır. Bazı bireylerde mental foramen birden fazla sayıda olabilmekte ve böyle vakalarda aksesuar mental foramen olarak adlandırılmaktadır. Aksesuar mental foramenler, mental foramene kıyasla daha küçük boyutlarda olmalarından dolayı genellikle geleneksel yöntemlerle görüntüleme esnasında teşhis edilememektedir. Konik-ışınlı bilgisayarlı tomografi, maksillofasiyal bölgedeki yapıların radyografik görüntülerinin her üç ortogonal düz...

  11. NL MIND-BEST: a web server for ligands and proteins discovery--theoretic-experimental study of proteins of Giardia lamblia and new compounds active against Plasmodium falciparum.

    Science.gov (United States)

    González-Díaz, Humberto; Prado-Prado, Francisco; Sobarzo-Sánchez, Eduardo; Haddad, Mohamed; Maurel Chevalley, Séverine; Valentin, Alexis; Quetin-Leclercq, Joëlle; Dea-Ayuela, María A; Teresa Gomez-Muños, María; Munteanu, Cristian R; José Torres-Labandeira, Juan; García-Mera, Xerardo; Tapia, Ricardo A; Ubeira, Florencio M

    2011-05-07

    There are many protein ligands and/or drugs described with very different affinity to a large number of target proteins or receptors. In this work, we selected Ligands or Drug-target pairs (DTPs/nDTPs) of drugs with high affinity/non-affinity for different targets. Quantitative Structure-Activity Relationships (QSAR) models become a very useful tool in this context to substantially reduce time and resources consuming experiments. Unfortunately most QSAR models predict activity against only one protein target and/or have not been implemented in the form of public web server freely accessible online to the scientific community. To solve this problem, we developed here a multi-target QSAR (mt-QSAR) classifier using the MARCH-INSIDE technique to calculate structural parameters of drug and target plus one Artificial Neuronal Network (ANN) to seek the model. The best ANN model found is a Multi-Layer Perceptron (MLP) with profile MLP 20:20-15-1:1. This MLP classifies correctly 611 out of 678 DTPs (sensitivity=90.12%) and 3083 out of 3408 nDTPs (specificity=90.46%), corresponding to training accuracy=90.41%. The validation of the model was carried out by means of external predicting series. The model classifies correctly 310 out of 338 DTPs (sensitivity=91.72%) and 1527 out of 1674 nDTP (specificity=91.22%) in validation series, corresponding to total accuracy=91.30% for validation series (predictability). This model favorably compares with other ANN models developed in this work and Machine Learning classifiers published before to address the same problem in different aspects. We implemented the present model at web portal Bio-AIMS in the form of an online server called: Non-Linear MARCH-INSIDE Nested Drug-Bank Exploration & Screening Tool (NL MIND-BEST), which is located at URL: http://miaja.tic.udc.es/Bio-AIMS/NL-MIND-BEST.php. This online tool is based on PHP/HTML/Python and MARCH-INSIDE routines. Finally we illustrated two practical uses of this server with two

  12. SPCE based glucose sensor employing novel thermostable glucose dehydrogenase, FADGDH: blood glucose measurement with 150nL sample in one second.

    Science.gov (United States)

    Yamaoka, Hideaki; Sode, Koji

    2007-01-01

    Self-monitoring of blood glucose (SMBG) is an important component of the modern therapy for diabetes mellitus. Thanks to the current progress in electronics and sensor fabrication technology, both the time and the blood sample volume required for the measurement have decreased drastically. However, devices that work with an even smaller sample volume and a shorter measurement time are in demand. A disposable glucose sensor that works with an ultra-small sample volume was developed employing the novel thermostable glucose-dehydrogenase (FADGDH) complex composed of a catalytic subunit, an electron transfer subunit (cytochrome c), and a small subunit. The electrode is a screen-printed carbon electrode (SPCE), and hexaammineruthenium (III) chloride (Ru complex) is utilized as the electron mediator. A disposable enzyme sensor was constructed by depositing the FADGDH complex and Ru complex onto the SPCE, and the sensor performance was evaluated. Whole-blood glucose can be measured within 1 sec using this enzyme sensor and a 150-nL whole-blood sample, with high precision (>0.99br>) and high reproducibility (CV) within the glucose concentration range of 0-533 mg/dL. The sensor reading was stable for more than 60 days even at 70 degrees C. The simplicity of the construction and the high precision of this FADGDH-based glucose biosensor makes it an alternative to previously reported commercially available glucose sensors. Especially the sample volume of 150 nL and the 1-sec measurement time are the highest specifications in the world for currently available glucose sensors designed for the SMBG.

  13. Sequence of pNL194, a 79.3-Kilobase IncN Plasmid Carrying the blaVIM-1 Metallo-β-Lactamase Gene in Klebsiella pneumoniae▿

    Science.gov (United States)

    Miriagou, V.; Papagiannitsis, C. C.; Kotsakis, S. D.; Loli, A.; Tzelepi, E.; Legakis, N. J.; Tzouvelekis, L. S.

    2010-01-01

    The nucleotide sequence of pNL194, a VIM-1-encoding plasmid, is described in this study. pNL194 (79,307 bp) comprised an IncN-characteristic segment (38,940 bp) and a mosaic structure (40,367 bp) including blaVIM-1, aacA7, aadA1, aadA2, dfrA1, dfrA12, aphA1, strA, strB, and sul1. Tn1000 or Tn5501 insertion within fipA probably facilitated recruitment of additional mobile elements carrying resistance genes. PMID:20660690

  14. Sequence of pNL194, a 79.3-kilobase IncN plasmid carrying the blaVIM-1 metallo-beta-lactamase gene in Klebsiella pneumoniae.

    Science.gov (United States)

    Miriagou, V; Papagiannitsis, C C; Kotsakis, S D; Loli, A; Tzelepi, E; Legakis, N J; Tzouvelekis, L S

    2010-10-01

    The nucleotide sequence of pNL194, a VIM-1-encoding plasmid, is described in this study. pNL194 (79,307 bp) comprised an IncN-characteristic segment (38,940 bp) and a mosaic structure (40,367 bp) including bla(VIM-1), aacA7, aadA1, aadA2, dfrA1, dfrA12, aphA1, strA, strB, and sul1. Tn1000 or Tn5501 insertion within fipA probably facilitated recruitment of additional mobile elements carrying resistance genes.

  15. Infinite dilution partial molar volumes of platinum(II) 2,4-pentanedionate in supercritical carbon dioxide.

    Science.gov (United States)

    Kong, Chang Yi; Siratori, Tomoya; Funazukuri, Toshitaka; Wang, Guosheng

    2014-10-03

    The effects of temperature and density on retention of platinum(II) 2,4-pentanedionate in supercritical fluid chromatography were investigated at temperatures of 308.15-343.15K and pressure range from 8 to 40MPa by the chromatographic impulse response method with curve fitting. The retention factors were utilized to derive the infinite dilution partial molar volumes of platinum(II) 2,4-pentanedionate in supercritical carbon dioxide. The determined partial molar volumes were small and positive at high pressures but exhibited very large and negative values in the highly compressible near critical region of carbon dioxide. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. Correction: Forrester, N.L.; Coffey, L.L.; Weaver, S.C. Arboviral Bottlenecks and Challenges to Maintaining Diversity and Fitness during Mosquito Transmission. Viruses 2014, 6, 3991–4004

    Directory of Open Access Journals (Sweden)

    Naomi L. Forrester

    2014-11-01

    Full Text Available In the original manuscript, Forrester, N.L.; Coffey, L.L.; Weaver, S.C. Arboviral Bottlenecks and Challenges to Maintaining Diversity and Fitness during Mosquito Transmission. Viruses 2014, 6, 3991–4004, Figure 1 contains an error, the third bottle was absent from the figure:[...

  17. Dietary intake of total, animal, and vegetable protein and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-NL study.

    Science.gov (United States)

    Sluijs, Ivonne; Beulens, Joline W J; van der A, Daphne L; Spijkerman, Annemieke M W; Grobbee, Diederick E; van der Schouw, Yvonne T

    2010-01-01

    Dietary recommendations are focused mainly on relative dietary fat and carbohydrate content in relation to diabetes risk. Meanwhile, high-protein diets may contribute to disturbance of glucose metabolism, but evidence from prospective studies is scarce. We examined the association among dietary total, vegetable, and animal protein intake and diabetes incidence and whether consuming 5 energy % from protein at the expense of 5 energy % from either carbohydrates or fat was associated with diabetes risk. A prospective cohort study was conducted among 38,094 participants of the European Prospective Investigation into Cancer and Nutrition (EPIC)-NL study. Dietary protein intake was measured with a validated food frequency questionnaire. Incident diabetes was verified against medical records. During 10 years of follow-up, 918 incident cases of diabetes were documented. Diabetes risk increased with higher total protein (hazard ratio 2.15 [95% CI 1.77-2.60] highest vs. lowest quartile) and animal protein (2.18 [1.80-2.63]) intake. Adjustment for confounders did not materially change these results. Further adjustment for adiposity measures attenuated the associations. Vegetable protein was not related to diabetes. Consuming 5 energy % from total or animal protein at the expense of 5 energy % from carbohydrates or fat increased diabetes risk. Diets high in animal protein are associated with an increased diabetes risk. Our findings also suggest a similar association for total protein itself instead of only animal sources. Consumption of energy from protein at the expense of energy from either carbohydrates or fat may similarly increase diabetes risk. This finding indicates that accounting for protein content in dietary recommendations for diabetes prevention may be useful.

  18. The effects of the final stages of the Late Ordovician glaciation on marine palynomorphs (chitinozoans, acritarchs, leiospheres) in well Nl-2 (NE Algerian Sahara).

    Science.gov (United States)

    Paris, F; Bourahrouh, A; Hérissé, A L.

    2000-12-01

    Palynomorph assemblages, especially chitinozoans and acritarchs, from the Upper Ordovician of well Nl-2 (north-east of the Algerian Sahara) are studied in order to precisely date the ultimate effects of the Late Ordovician glaciation and to document the impact of this major climatic stress on the diversity of the palynoplankton. References are made to stable isotope excursions and to global eustatic sea level variations in order to improve the local age determination. The Hassi el Hadjar Formation, i.e. glacio-marine diamictites, is interpreted as a transgressive event resulting from the melting of the northern Gondwana ice cap. It yields poorly preserved and moderately diverse chitinozoans of late Hirnantian age. Acritarchs are more abundant in the lower part of these "microconglomeratic clays", but display a low diversity and are badly preserved throughout the whole formation. Reworked individuals are recorded in both groups. The marine sediments of the M'Kratta Formation of latest Hirnantian age contain better preserved, more abundant and more diverse palynomorph assemblages, especially in the Upper Member. The composition of this palynoplankton indicates a fairly good faunal and phytoplankton recovery after the early Hirnantian climatic stress.The extinction of the Ordovician forms, and the appearance of Silurian type taxa occur only in the uppermost Hirnantian, i.e. following with a slight delay the glacial event. The overlying black shales of Wenlock age (lower part of the Oued Mehaiguène Formation) are indicative of marine anoxic environments. They yield a virtually exclusive, but enormous number of Tasmanacea. The very peculiar composition of this palynoplankton seems to be independent of the Late Ordovician glaciation and is most likely related to the factors that, later, generated and maintained anoxic conditions in this area.A new species of chitinozoan, Spinachitina oulebsiri sp. nov. from the latest Hirnantian M'Kratta Formation, is described and

  19. Reducing our environmental footprint and improving our health: greenhouse gas emission and land use of usual diet and mortality in EPIC-NL: a prospective cohort study.

    Science.gov (United States)

    Biesbroek, Sander; Bueno-de-Mesquita, H Bas; Peeters, Petra H M; Verschuren, Wm Monique; van der Schouw, Yvonne T; Kramer, Gerard F H; Tyszler, Marcelo; Temme, Elisabeth H M

    2014-04-07

    Food choices influence health status, but also have a great impact on the environment. The production of animal-derived foods has a high environmental burden, whereas the burden of refined carbohydrates, vegetables and fruit is low. The aim of this study was to investigate the associations of greenhouse gas emission (GHGE) and land use of usual diet with mortality risk, and to estimate the effect of a modelled meat substitution scenario on health and the environment. The usual diet of 40011 subjects in the EPIC-NL cohort was assessed using a food frequency questionnaire. GHGE and land use of food products were based on life cycle analysis. Cox proportional hazard ratios (HR) were calculated to determine relative mortality risk. In the modelled meat-substitution scenario, one-third (35 gram) of the usual daily meat intake (105 gram) was substituted by other foods. During a follow-up of 15.9 years, 2563 deaths were registered. GHGE and land use of the usual diet were not associated with all-cause or with cause-specific mortality. Highest vs. lowest quartile of GHGE and land use adjusted hazard ratios for all-cause mortality were respectively 1.00 (95% CI: 0.86-1.17) and 1.05 (95% CI: 0.89-1.23). Modelled substitution of 35 g/d of meat with vegetables, fruit-nuts-seeds, pasta-rice-couscous, or fish significantly increased survival rates (6-19%), reduced GHGE (4-11%), and land use (10-12%). There were no significant associations observed between dietary-derived GHGE and land use and mortality in this Dutch cohort. However, the scenario-study showed that substitution of meat with other major food groups was associated with a lower mortality risk and a reduced environmental burden. Especially when vegetables, fruit-nuts-seeds, fish, or pasta-rice-couscous replaced meat.

  20. Summary of surface-water-quality data collected for the Northern Rockies Intermontane Basins National Water-Quality Assessment Program in the Clark Fork-Pend Oreille and Spokane River basins, Montana, Idaho, and Washington, water years 1999-2001

    Science.gov (United States)

    Beckwith, Michael A.

    2003-01-01

    Water-quality samples were collected at 10 sites in the Clark Fork-Pend Oreille and Spokane River Basins in water years 1999 – 2001 as part of the Northern Rockies Intermontane Basins (NROK) National Water-Quality Assessment (NAWQA) Program. Sampling sites were located in varied environments ranging from small streams and rivers in forested, mountainous headwater areas to large rivers draining diverse landscapes. Two sampling sites were located immediately downstream from the large lakes; five sites were located downstream from large-scale historical mining and oreprocessing areas, which are now the two largest “Superfund” (environmental remediation) sites in the Nation. Samples were collected during a wide range of streamflow conditions, more frequently during increasing and high streamflow and less frequently during receding and base-flow conditions. Sample analyses emphasized major ions, nutrients, and selected trace elements. Streamflow during the study ranged from more than 130 percent of the long-term average in 1999 at some sites to 40 percent of the long-term average in 2001. River and stream water in the study area exhibited small values for specific conductance, hardness, alkalinity, and dissolved solids. Dissolved oxygen concentrations in almost all samples were near saturation. Median total nitrogen and total phosphorus concentrations in samples from most sites were smaller than median concentrations reported for many national programs and other NAWQA Program study areas. The only exceptions were two sites downstream from large wastewater-treatment facilities, where median concentrations of total nitrogen exceeded the national median. Maximum concentrations of total phosphorus in samples from six sites exceeded the 0.1 milligram per liter threshold recommended for limiting nuisance aquatic growth. Concentrations of arsenic, cadmium, copper, lead, mercury, and zinc were largest in samples from sites downstream from historical mining and ore

  1. Isolation and genetic characterization of human coronavirus NL63 in primary human renal proximal tubular epithelial cells obtained from a commercial supplier, and confirmation of its replication in two different types of human primary kidney cells.

    Science.gov (United States)

    Lednicky, John A; Waltzek, Thomas B; McGeehan, Elizabeth; Loeb, Julia C; Hamilton, Sara B; Luetke, Maya C

    2013-06-27

    Cryopreserved primary human renal proximal tubule epithelial cells (RPTEC) were obtained from a commercial supplier for studies of Simian virus 40 (SV40). Within twelve hrs after cell cultures were initiated, cytoplasmic vacuoles appeared in many of the RPTEC. The RPTEC henceforth deteriorated rapidly. Since SV40 induces the formation of cytoplasmic vacuoles, this batch of RPTEC was rejected for the SV40 study. Nevertheless, we sought the likely cause(s) of the deterioration of the RPTEC as part of our technology development efforts. Adventitious viruses in the RPTEC were isolated and/or detected and identified by isolation in various indicator cell lines, observation of cytopathology, an immunoflurorescence assay, electron microscopy, PCR, and sequencing. Cytomegalovirus (CMV) was detected in some RPTEC by cytology, an immunofluorescence assay, and PCR. Human Herpesvirus 6B was detected by PCR of DNA extracted from the RPTEC, but was not isolated. Human coronavirus NL63 was isolated and identified by RT-PCR and sequencing, and its replication in a fresh batch of RPTEC and another type of primary human kidney cells was confirmed. At least 3 different adventitious viruses were present in the batch of contaminated RPTEC. Whereas we are unable to determine whether the original RPTEC were pre-infected prior to their separation from other kidney cells, or had gotten contaminated with HCoV-NL63 from an ill laboratory worker during their preparation for commercial sale, our findings are a reminder that human-derived biologicals should always be considered as potential sources of infectious agents. Importantly, HCoV-NL63 replicates to high titers in some primary human kidney cells.

  2. Spectrophotometric Determination of Methimazole in Pharmaceutical Sample by Fe(II)-2,2’-Bipyridyl System

    Science.gov (United States)

    Wen, Xinrong; Tu, Changqing

    2017-12-01

    By controlling pH=5.0, Fe(III) could be reduced to Fe(II) by hydrosulfuryl (-SH) in methimazole molecule, then Fe(II) reacts with 2,2‧-bipyridyl to form the orange red complex which the maximum absorption is at 522nm. The content of methimazole can be measured by measuring the amount of the complex of Fe(II)-2,2‧-bipyridyl. A accurate fast spectrophotometric method for the determination the content of methimazole had been established. A good linear relationship was obtained between A and the concentration of methimazole in the range of 0.0004000-0.004000mg/mL, the equation of the linear regression was A=0.02707+136.29C(mg/mL), with a linear correlation coefficient was 0.9994. This proposed method had been successfully applied to determinate of methimazole in real pharmaceutical.

  3. New potentiometric transducer based on a Mn(II) [2-formylquinoline thiosemicarbazone] complex for static and hydrodynamic assessment of azides.

    Science.gov (United States)

    Kamel, Ayman H

    2015-11-01

    A new potentiometric transducer for selective recognition of azide is characterized and developed. The PVC plasticized based sensor incorporates Mn(II) [2-formylquinoline thiosemicarbazone] complex in the presence of tri dodecyl methyl ammonium chloride (TDMAC) as a lipophilic cationic additive. The sensor displayed a near-Nernstian response for azide over 1.0×10(-2)-1.0×10(-5) mol L(-1), with an anionic slope of -55.8±0.6 mV decade(-1) and lower limit of detection 0.34 µg mL(-1). The sensor was pH independent in the range 5.5-9 and presented good selectivity features towards several inorganic anions, and it is easily used in a flow injection system and compared with a tubular detector. The intrinsic characteristics of the detector in a low dispersion manifold were determined and compared with data obtained under a hydrodynamic mode of operation. This simple and inexpensive automation, with a good potentiometric detector, enabled the analysis of ~33 samples h(-1) without requiring pre-treatment procedures. The proposed method is also applied to the analysis of trace levels of azide in primer mixtures. Significantly improved accuracy, precision, response time, stability and selectivity were offered by these simple and cost-effective potentiometric sensor compared with other standard techniques. The method has the requisite accuracy, sensitivity and precision to determine azide ions. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Karabük İçin Dış Duvar Optimum Yalıtım Kalınlığının Enerji Tasarrufu Ve Hava Kirliliğine Etkileri

    Directory of Open Access Journals (Sweden)

    Ali Etem Gürel

    2012-12-01

    Full Text Available ÖzetBina dış duvarlarında yapılacak ısı yalıtım uygulamaları, yakıt tüketimini düşürerek enerji tasarrufu sağlamanın yanında, fosil kaynaklı yakıt kullanımından kaynaklanan ve hava kirliliğine neden olan emisyonların düşürülmesinde de son derece etkilidir. Bu çalışmada Karabük’te kömür ve doğalgaz kullanımında dış duvar optimum yalıtım kalınlığı tespitinin ekonomik ve çevresel analizi yapılmıştır. Çalışmanın ekonomik boyutu, yaşam döngüsü maliyet analizine (LCCA dayanan P1-P2 yöntemi ile gerçekleştirilmiştir. Çalışmanın sonuçları, yakıt olarak kömür kullanıldığında optimum yalıtım kalınlığı ve enerji tasarrufunun sırasıyla 0.134 m ve 117.14 TL/m² olduğunu göstermiştir. Yakıt olarak doğalgaz kullanımında ise bu değerler sırasıyla 0.116 m ve 88.39 TL/m² olarak bulunmuştur. Optimum yalıtım kalınlığının hava kirliliğine olan etkileri incelendiğinde, yalıtımsız bina dış duvarında hesaplanan CO2 ve SO2 emisyonlarının yakıt tipine bağlı olarak optimum yalıtım kalınlığı noktasında %85.4’e kadar azaldığı hesaplanmıştır.AbstractHeat insulation applications carried out on external walls of building provides energy saving by decreasing fuel consumption and also quite important in decreasing emission which results from fossil-based fuel usage and causes air pollution. In this study, economic and environmental analyses were done for determination of external wall optimum thickness in using coal and natural gas usage in Karabük. Economic extent of the study was done with P1-P2 method which is based on life cycle cost analysis (LCCA. The results show that optimum insulation thickness and energy saving are 0.134 m and 117.14 TL/m² respectively when coal is used as a fuel. These values are 0.116 m and 88.39 TL/m² when natural gas is used as fuel. When the effects of optimum insulation thickness on air pollution are observed, CO2

  5. Birinci basamak Helikobakter pilori eradikasyon tedavisinde 7 ve 14 günlük lansoprazol, amoksisilin, metronidazol protokolünün karşılaştırılması

    OpenAIRE

    UYGUN, Ahmet; KANTARCIOĞLU, Murat; POLAT, Zülfikar; KİLCİLER, Güldem; GÜLŞEN, Mustafa

    2010-01-01

    Giriş ve Amaç: Ülkemizde günümüzde birinci basamak Helikobakter pilori eradikasyon tedavisinde protokollerin süresi ve eradikasyon oranları konusunda tartışmalar sürmektedir. Bu çalışmadaki amacımız; nonülser dispepsili Helikobakter pilori pozitif hastalarda lansoprazol, amoksisilin, metronidazol'den oluşan 7 ve 14 günlük tedavi protokollerinin eradikasyon oranlarını karşılaştırmaktır. Gereç ve Yöntem: Çalışmaya Helikobakter pilori pozitif nonülser dispepsili 180 hasta (84 kadın,...

  6. Helicobacter pylori eradikasyon tedavisinde 7 ve 14 günlük lansoprazol, amoksisilin, klaritromisin protokolünün karşılaştırılması

    OpenAIRE

    UYGUN, Ahmet; TÜZÜN, Ahmet; YEŞİLOVA, Zeki; ASLAN, Murat; ATEŞ, Yüksel; POLAT, Zülfikar; ERDİL, Ahmet; BAĞCI, Sait; GÜNHAN, Ömer; GÜLŞEN, Mustafa; DAĞALP, Kemal

    2015-01-01

    Giriş ve amaç: Günümüzde birinci basamak Helicobacter pylori (Hp) eradikasyon tedavisinde protokollerin süresi ve eradikasyon oranları konusunda tartışmalar sürmektedir. Bu çalışmadaki amacımız; nonülser dispepsili Hp pozitif hastalarda lansoprazol, klaritromisin ve amoksisilin'den oluşan 7 ve 14 günlük tedavi protokollerinin eradikasyon oranları nı karşılaştırmaktır. Gereç ve yöntem: Çalışmaya Hp pozitif nonülser dispepsili 188 hasta (92 kadın, 96 erkek, ortalama yaş 44.8 yıl) alı...

  7. Improving the production yield and productivity of 1,3-dihydroxyacetone from glycerol fermentation using Gluconobacter oxydans NL71 in a compressed oxygen supply-sealed and stirred tank reactor (COS-SSTR).

    Science.gov (United States)

    Zhou, Xin; Zhou, Xuelian; Xu, Yong; Yu, Shiyuan

    2016-08-01

    In this study, a compressed oxygen gas supply was connected to a sealed aerated stirred tank reactor (COS-SSTR) bio-system, leading to a high-oxygen pressure bioreactor used to improve the bio-transformative performance in the production of 1,3-dihydroxyacetone (DHA) from glycerol using Gluconobacter oxydans NL71. A concentration of 301.2 ± 8.2 g L(-1) DHA was obtained from glycerol after 32 h of fed-batch fermentation in the COS-SSTR system. The volumetric productivity for this process was 9.41 ± 0.23 g L(-1) h(-1), which is presently the highest obtained level of glycerol bioconversion into DHA. These results show that the application of this bioreactor would enable microbial production of DHA from glycerol at the industrial scale.

  8. In Silico Analysis for Transcription Factors With Zn(II2C6 Binuclear Cluster DNA-Binding Domains in Candida albicans

    Directory of Open Access Journals (Sweden)

    Sergi Maicas

    2005-01-01

    presence of the CysX2CysX6CysX5-16CysX2CysX6-8Cys motif and a putative nuclear localization signal. Using this approach, 70 putative Zn(II2C6 transcription factors have been found in the genome of C. albicans.

  9. Çokkültürlülük ve Yurtseverlik Bağlamında Azınlık Öğrencilerinin Tarih Dersleriyle İlgili Algıları

    Directory of Open Access Journals (Sweden)

    Fatih YAZICI

    2015-10-01

    Full Text Available Bu araştırmada, Türkiye’deki azınlık okullarına devam eden lise öğrencilerinin tarih dersleriyle ilgili görüşlerinin çokkültürlülük ve yurtseverlik bağlamında değerlendirilmesi amaçlanmıştır. Araştırmanın çalışma grubunu kasti örneklem yöntemiyle seçilen, İstanbul’un çeşitli ilçelerindeki azınlık okulunda öğrenim gören 199 öğrenci oluşturmaktadır. Bu çalışma grubundan veri toplamak amacıyla araştırmacılar tarafından geliştirilen Çokkültürlülük Tutum Ölçeği, Yurtseverlik Ölçeği ve tarih derslerini kendi kimlikleri açısından değerlendirmelerini amaçlayan bir anket uygulanmıştır. Verilerin analizinde aritmetik ortalama, standart sapma ve t-testi kullanılmıştır. Araştırmaya katılan öğrencilerin çoğunluğu tarih derslerinde kendi kültürel kimliklerinin yeterince yer bulamadığını, bu kimliklere yer veren bölümlerde ise ötekileştirici bir söylemin kullanıldığını belirtmişlerdir. Tarih dersleri, kültürel farklılığa sahip öğrenciler için bu şekliyle, yurtseverlik duygusu oluşturmanın uzağında kalmaktadır.Anahtar Kelimeler: Tarih Öğretimi, Çokkültürlülük, Yurtseverlik, Çokkültürlü Eğitim, Azınlık Okulları PERCEPTION of MINORITY STUDENTS about HISTORY LESSONS in the CONTEXT of MULTICULTURALISM and PATRIOTISMAbstract: The purpose of this study is to evaluate perceptions of students who attend minority school with respect to history lessons in the context of multiculturalism and patriotism in Turkey. The study group consists of intentionally chosen 199 students attending at different minority schools in Istanbul. Survey method was used in this study. The Multiculturalism Attitude Scale, Patriotism Scale and a questionnaire, developed by the researchers, examining cultural diversity in history lessons were used. In analyzing date, t- test, arithmetic mean and standard deviation were used. The findings of the study indicated

  10. nlük Yaşamdaki Kimya Kavram Yanılgılarının Atasözleri İle Tespit Edilmesi

    OpenAIRE

    Yavuz, Soner; Büyükekşi, Cem

    2016-01-01

    Kavram yanılgıları, kimya öğretiminde öğrenci ve öğretmenler için sıkıntı verici bir sorundur. Öğrencilerin sahip oldukları bu fikirler bilimsel olarak tutarsız düşünce, önyargı ve yaşam deneyimlerini ortaya koymaktadır. Bu durum, öğrencilerin kimya konularını doğru olarak öğrenmelerini güçleştirmektedir. Araştırmada, öğrencilerin günlük yaşam konularında sahip oldukları kavram yanılgılarının tespit edilmesi amaçlanmıştır. Bu amaç doğrultusunda, öğrencilerin sahip olduğu kavram yanılgıları Ar...

  11. In arthritis the Doppler based degree of hypervascularisation shows a positive correlation with synovial leukocyte count and distinguishes joints with leukocytes greater and less than 5/nL.

    Science.gov (United States)

    Löffler, Christian; Sattler, Horst; Peters, Lena; Tuleweit, Anika; Löffler, Uta; Wadsack, Daniel; Uppenkamp, Michael; Bergner, Raoul

    2016-10-01

    Power Doppler ultrasound is used to assess joint vascularity in acute arthritis. PDUS signals have been correlated with synovial histology and bone deterioration. Little is known about the correlation between power Doppler signals and synovial white blood count. In our study, we analyzed power Doppler signals in inflammatory joint diseases including gout, calcium pyrophosphate deposition disease, rheumatoid arthritis, spondyloarthritis and others and correlated power Doppler signals with synovial white blood count and with serologic markers of inflammation. We retrospectively evaluated 194 patients with arthritis. All patients underwent joint sonography, power Doppler ultrasound, synovial fluid analysis and blood examination of C-reactive protein and erythrocyte sedimentation rate. Correlation analyses (Spearman and Pearson), Chi(2) test, t-tests, a unifactorial ANOVA and regression analyses were applied. Hypervascularisation in power Doppler was most prominent in gout and calcium pyrophosphate deposition disease. Spondyloarthritis and non-inflammatory joint diseases presented with low degrees of hypervascularisation. Mean synovial white blood count did not differ significantly between crystal-related arthritides, rheumatoid arthritis, spondyloarthritis or other inflammatory joint diseases. There was a positive but weak correlation between power Doppler signals and synovial white blood count (Pleukocytesleukocytes≥5/nL (P<0.001). Copyright © 2016 Société française de rhumatologie. Published by Elsevier SAS. All rights reserved.

  12. Uranium: a foreign resource N.L

    International Nuclear Information System (INIS)

    Venturini, V.G.

    1983-01-01

    The issue of the mining and export of Australian uranium is examined. Particular reference is made to the existence of a uranium cartel between 1970 and 1975 and the associated U.S. Westinghouse Antitrust suite. Problems associated with nuclear power and benefits to Australia associated with the mining of uranium are questioned. Changing government policy on the issue is discussed. Recommendations of the Ranger uranium environmental enquiry are noted

  13. DATA.KNMI.NL - Status & Future Challenges

    Science.gov (United States)

    van de Vegte, John; Som de Cerff, Wim; Verhoef, Hans; Plieger, Maarten; de Vreede, Ernst; van der Neut, Ian; Bos, Jeroen; Ha, Siu-Siu; Sluiter, Raymond; Willem Noteboom, Jan; Klein Baltink, Henk; Reijmerink, Mieke

    2015-04-01

    The Royal Netherlands Meteorological Institute (KNMI) has over 150 years of knowledge and gathered information related to weather, Climate and Seismology. A huge part of this information is from numerical models, insitu sensor networks and remote sensing satellites. This digital collection is becoming more and more available in the newly developed KNMI Data Centre, that is now 2 years operational. The KNMI Data Centre project has a user driven development approach where SCRUM is chosen to get maximum user involvement in a relative short timeframe. The system is build on open standards and proven opensource technology (which includes in-house developed software like ADAGUC WMS and Portal). The presentation will focus on the aspects of developing the initial KNMI Data Centre, the operational use of the last 2 years, and how a major release for the coming year will be realized. The new release which will focus on better user experience and extending the technical data interfaces to the data centre. Keywords: Agile, Usage Statistics, Open Data, Inspire, DOI, WMS, WCS, OPeNDAP

  14. Outcome quality and long-term (≥15 years) stability after Class II:2 Herbst-multibracket appliance treatment in comparison to untreated Class I controls.

    Science.gov (United States)

    Bock, Niko C; Saffar, Mitra; Hudel, Helge; Evälahti, Marjut; Heikinheimo, Kaisa; Rice, David P; Ruf, Sabine

    2017-12-09

    To investigate the outcome quality and the long-term (≥15 years) post-treatment (Tx) changes after Class II:2 Herbst-multibracket appliance (MBA) Tx. In this longitudinal observational study, a recall of Class II:2 patients who had been treated by a Herbst-MBA during adolescence was conducted. Study models from before and after active Tx, after retention and after recall were assessed using standard occlusal variables and the peer assessment rating index (PAR). These data were compared to historical untreated Class I controls. Twenty out of 33 patients (61%) could be located and participated at age 33.9 ± 2.7 years. When comparing their data to the 13 patients who did not participate, the pre- and post-Tx occlusal findings did not differ systematically; however, the PAR scores of the non-participants were by 3.3-8.2 points higher at all times and the non-participants were 2.1-2.5 years older. Pre-Tx at age 14.4 ± 2.7 years, the participants showed the following mean values: PAR = 15.0 ± 7.0, Class II molar relationship (MR) = 0.8 ± 0.3 cusp widths (cw), overbite = 5.3 ± 1.3 mm. After Tx, a PAR score of 2.9 ± 1.3 and a super Class I MR (-0.1 ± 0.1 cw) with normal overbite (1.2 ± 0.8 mm) existed. At recall, a PAR score increase to 5.9 ± 3.6 points had occurred, mainly caused by an increase of overbite to 2.5 ± 1.5 mm. The average MR remained Class I (0.0 ± 0.2 cw). For all variables, the untreated controls exhibited similar findings. The occlusal outcome of Class II:2 Herbst-MBA Tx exhibited very good long-term stability. While mild post-Tx changes occurred, the long-term findings are similar to untreated Class I controls. © The Author(s) 2017. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. For permissions, please email: journals.permissions@oup.com

  15. Multireversible redox processes in pentanuclear bis(triple-helical) manganese complexes featuring an oxo-centered triangular {Mn(II)2Mn(III)(μ3-O)}5+ or {Mn(II)Mn(III)2(μ3-O)}6+ core wrapped by two {Mn(II)2(bpp)3}-.

    Science.gov (United States)

    Romain, Sophie; Rich, Jordi; Sens, Cristina; Stoll, Thibaut; Benet-Buchholz, Jordi; Llobet, Antoni; Rodriguez, Montserrat; Romero, Isabel; Clérac, Rodolphe; Mathonière, Corine; Duboc, Carole; Deronzier, Alain; Collomb, Marie-Noëlle

    2011-09-05

    A new pentanuclear bis(triple-helical) manganese complex has been isolated and characterized by X-ray diffraction in two oxidation states: [{Mn(II)(μ-bpp)(3)}(2)Mn(II)(2)Mn(III)(μ-O)](3+) (1(3+)) and [{Mn(II)(μ-bpp)(3)}(2)Mn(II)Mn(III)(2)(μ-O)](4+) (1(4+)). The structure consists of a central {Mn(3)(μ(3)-O)} core of Mn(II)(2)Mn(III) (1(3+)) or Mn(II)Mn(III)(2) ions (1(4+)) which is connected to two apical Mn(II) ions through six bpp(-) ligands. Both cations have a triple-stranded helicate configuration, and a pair of enantiomers is present in each crystal. The redox properties of 1(3+) have been investigated in CH(3)CN. A series of five distinct and reversible one-electron waves is observed in the -1.0 and +1.50 V potential range, assigned to the Mn(II)(4)Mn(III)/Mn(II)(5), Mn(II)(3)Mn(III)(2)/Mn(II)(4)Mn(III), Mn(II)(2)Mn(III)(3)/Mn(II)(3)Mn(III)(2), Mn(II)Mn(III)(4)/Mn(II)(2)Mn(III)(3), and Mn(III)(5)/Mn(II)Mn(III)(4) redox couples. The two first oxidation processes leading to Mn(II)(3)Mn(III)(2) (1(4+)) and Mn(II)(2)Mn(III)(3) (1(5+)) are related to the oxidation of the Mn(II) ions of the central core and the two higher oxidation waves, close in potential, are thus assigned to the oxidation of the two apical Mn(II) ions. The 1(4+) and 1(5+) oxidized species and the reduced Mn(4)(II) (1(2+)) species are quantitatively generated by bulk electrolyses demonstrating the high stability of the pentanuclear structure in four oxidation states (1(2+) to 1(5+)). The spectroscopic characteristics (X-band electron paramagnetic resonance, EPR, and UV-visible) of these species are also described as well as the magnetic properties of 1(3+) and 1(4+) in solid state. The powder X- and Q-band EPR signature of 1(3+) corresponds to an S = 5/2 spin state characterized by a small zero-field splitting parameter (|D| = 0.071 cm(-1)) attributed to the two apical Mn(II) ions. At 40 K, the magnetic behavior is consistent for 1(3+) with two apical S = 5/2 {Mn(II)(bpp)(3)}(-) and one S

  16. Truck freight commodity flows : US 395 North of Spokane Washington,

    Science.gov (United States)

    2014-10-01

    The search for understanding of commodity flows throughout the nation and the State of : Washington is a continual process. This understanding is critical at many levels of the : transportation industry and to those firms and entities that provide th...

  17. Order Denying Review -- Spokane Regional Waste to Energy

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  18. Tpc1 is an important Zn(II2Cys6 transcriptional regulator required for polarized growth and virulence in the rice blast fungus.

    Directory of Open Access Journals (Sweden)

    Rita Galhano

    2017-07-01

    Full Text Available The establishment of polarity is a critical process in pathogenic fungi, mediating infection-related morphogenesis and host tissue invasion. Here, we report the identification of TPC1 (Transcription factor for Polarity Control 1, which regulates invasive polarized growth in the rice blast fungus Magnaporthe oryzae. TPC1 encodes a putative transcription factor of the fungal Zn(II2Cys6 family, exclusive to filamentous fungi. Tpc1-deficient mutants show severe defects in conidiogenesis, infection-associated autophagy, glycogen and lipid metabolism, and plant tissue colonisation. By tracking actin-binding proteins, septin-5 and autophagosome components, we show that Tpc1 regulates cytoskeletal dynamics and infection-associated autophagy during appressorium-mediated plant penetration. We found that Tpc1 interacts with Mst12 and modulates its DNA-binding activity, while Tpc1 nuclear localisation also depends on the MAP kinase Pmk1, consistent with the involvement of Tpc1 in this signalling pathway, which is critical for appressorium development. Importantly, Tpc1 directly regulates NOXD expression, the p22phox subunit of the fungal NADPH oxidase complex via an interaction with Mst12. Tpc1 therefore controls spatial and temporal regulation of cortical F-actin through regulation of the NADPH oxidase complex during appressorium re-polarisation. Consequently, Tpc1 is a core developmental regulator in filamentous fungi, linking the regulated synthesis of reactive oxygen species and the Pmk1 pathway, with polarity control during host invasion.

  19. Cardiovascular risk prediction in HIV-infected patients: comparing the Framingham, atherosclerotic cardiovascular disease risk score (ASCVD), Systematic Coronary Risk Evaluation for the Netherlands (SCORE-NL) and Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) risk prediction models.

    Science.gov (United States)

    Krikke, M; Hoogeveen, R C; Hoepelman, A I M; Visseren, F L J; Arends, J E

    2016-04-01

    The aim of the study was to compare the predictions of five popular cardiovascular disease (CVD) risk prediction models, namely the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) model, the Framingham Heart Study (FHS) coronary heart disease (FHS-CHD) and general CVD (FHS-CVD) models, the American Heart Association (AHA) atherosclerotic cardiovascular disease risk score (ASCVD) model and the Systematic Coronary Risk Evaluation for the Netherlands (SCORE-NL) model. A cross-sectional design was used to compare the cumulative CVD risk predictions of the models. Furthermore, the predictions of the general CVD models were compared with those of the HIV-specific D:A:D model using three categories ( 20%) to categorize the risk and to determine the degree to which patients were categorized similarly or in a higher/lower category. A total of 997 HIV-infected patients were included in the study: 81% were male and they had a median age of 46 [interquartile range (IQR) 40-52] years, a known duration of HIV infection of 6.8 (IQR 3.7-10.9) years, and a median time on ART of 6.4 (IQR 3.0-11.5) years. The D:A:D, ASCVD and SCORE-NL models gave a lower cumulative CVD risk, compared with that of the FHS-CVD and FHS-CHD models. Comparing the general CVD models with the D:A:D model, the FHS-CVD and FHS-CHD models only classified 65% and 79% of patients, respectively, in the same category as did the D:A:D model. However, for the ASCVD and SCORE-NL models, this percentage was 89% and 87%, respectively. Furthermore, FHS-CVD and FHS-CHD attributed a higher CVD risk to 33% and 16% of patients, respectively, while this percentage was D:A:D, ASCVD and SCORE-NL models. This could have consequences regarding overtreatment, drug-related adverse events and drug-drug interactions. © 2015 British HIV Association.

  20. Ab initio structural modeling of and experimental validation for Chlamydia trachomatis protein CT296 reveal structural similarity to Fe(II) 2-oxoglutarate-dependent enzymes

    Energy Technology Data Exchange (ETDEWEB)

    Kemege, Kyle E.; Hickey, John M.; Lovell, Scott; Battaile, Kevin P.; Zhang, Yang; Hefty, P. Scott (Michigan); (Kansas); (HWMRI)

    2012-02-13

    Chlamydia trachomatis is a medically important pathogen that encodes a relatively high percentage of proteins with unknown function. The three-dimensional structure of a protein can be very informative regarding the protein's functional characteristics; however, determining protein structures experimentally can be very challenging. Computational methods that model protein structures with sufficient accuracy to facilitate functional studies have had notable successes. To evaluate the accuracy and potential impact of computational protein structure modeling of hypothetical proteins encoded by Chlamydia, a successful computational method termed I-TASSER was utilized to model the three-dimensional structure of a hypothetical protein encoded by open reading frame (ORF) CT296. CT296 has been reported to exhibit functional properties of a divalent cation transcription repressor (DcrA), with similarity to the Escherichia coli iron-responsive transcriptional repressor, Fur. Unexpectedly, the I-TASSER model of CT296 exhibited no structural similarity to any DNA-interacting proteins or motifs. To validate the I-TASSER-generated model, the structure of CT296 was solved experimentally using X-ray crystallography. Impressively, the ab initio I-TASSER-generated model closely matched (2.72-{angstrom} C{alpha} root mean square deviation [RMSD]) the high-resolution (1.8-{angstrom}) crystal structure of CT296. Modeled and experimentally determined structures of CT296 share structural characteristics of non-heme Fe(II) 2-oxoglutarate-dependent enzymes, although key enzymatic residues are not conserved, suggesting a unique biochemical process is likely associated with CT296 function. Additionally, functional analyses did not support prior reports that CT296 has properties shared with divalent cation repressors such as Fur.

  1. PHISICS/RELAP5-3D RESULTS FOR EXERCISES II-1 AND II-2 OF THE OECD/NEA MHTGR-350 BENCHMARK

    Energy Technology Data Exchange (ETDEWEB)

    Strydom, Gerhard [Idaho National Laboratory

    2016-03-01

    The Idaho National Laboratory (INL) Advanced Reactor Technologies (ART) High-Temperature Gas-Cooled Reactor (HTGR) Methods group currently leads the Modular High-Temperature Gas-Cooled Reactor (MHTGR) 350 benchmark. The benchmark consists of a set of lattice-depletion, steady-state, and transient problems that can be used by HTGR simulation groups to assess the performance of their code suites. The paper summarizes the results obtained for the first two transient exercises defined for Phase II of the benchmark. The Parallel and Highly Innovative Simulation for INL Code System (PHISICS), coupled with the INL system code RELAP5-3D, was used to generate the results for the Depressurized Conduction Cooldown (DCC) (exercise II-1a) and Pressurized Conduction Cooldown (PCC) (exercise II-2) transients. These exercises require the time-dependent simulation of coupled neutronics and thermal-hydraulics phenomena, and utilize the steady-state solution previously obtained for exercise I-3 of Phase I. This paper also includes a comparison of the benchmark results obtained with a traditional system code “ring” model against a more detailed “block” model that include kinetics feedback on an individual block level and thermal feedbacks on a triangular sub-mesh. The higher spatial fidelity that can be obtained by the block model is illustrated with comparisons of the maximum fuel temperatures, especially in the case of natural convection conditions that dominate the DCC and PCC events. Differences up to 125 K (or 10%) were observed between the ring and block model predictions of the DCC transient, mostly due to the block model’s capability of tracking individual block decay powers and more detailed helium flow distributions. In general, the block model only required DCC and PCC calculation times twice as long as the ring models, and it therefore seems that the additional development and calculation time required for the block model could be worth the gain that can be

  2. Synthesis and surface chemistry of high quality wurtzite and kesterite Cu2ZnSnS4 nanocrystals using tin(II) 2-ethylhexanoate as a new tin source.

    Science.gov (United States)

    Gabka, Grzegorz; Bujak, Piotr; Gryszel, Maciej; Ostrowski, Andrzej; Malinowska, Karolina; Zukowska, Grazyna Z; Agnese, Fabio; Pron, Adam; Reiss, Peter

    2015-08-21

    A novel synthesis method for the preparation of Cu2ZnSnS4 nanocrystals is presented using a liquid precursor of tin, namely tin(II) 2-ethylhexanoate, which yields small and nearly monodisperse NCs either in the kesterite or in the wurtzite phase depending on the sulfur source (elemental sulfur in oleylamine vs. dodecanethiol).

  3. Synthesis and surface chemistry of high quality wurtzite and kesterite Cu2ZnSnS4 nanocrystals using tin(II) 2-ethylhexanoate as a new tin source

    NARCIS (Netherlands)

    Gabka, Grzegorz; Bujak, Piotr; Gryszel, Maciej; Ostrowski, Andrzej; Malinowska, Karolina; Zukowska, Grazyna Z.; Agnese, Fabio; Pron, Adam; Reiss, Peter

    2015-01-01

    A novel synthesis method for the preparation of Cu2ZnSnS4 nanocrystals is presented using a liquid precursor of tin, namely tin(II) 2-ethylhexanoate, which yields small and nearly monodisperse NCs either in the kesterite or in the wurtzite phase depending on the sulfur source (elemental sulfur in

  4. Yeni Tanılı Diyabetes Mellitus Hastalarında Peripapiller Retina Sinir Lifi Tabakası Ve Subfoveal Koroid Kalınlığının Spektralis OCT İle Değerlendirilmesi

    Directory of Open Access Journals (Sweden)

    Muhammed Şahin

    2016-09-01

    Full Text Available Amaç: Bu çalışmada amacımız, yeni tanı alan ve her­hangi bir diyabetik retinopati (DR bulgusu olmayan tip 2 diyabetes mellituslu (DM olgularla sağlıklı bireylerin peri­papiller retina sinir lifi tabakası (pRSLT ve koroid tabaka­sı kalınlıklarını karşılaştırmaktır. Yöntemler: Çalışmaya Endokrin polikliniğinden yeni tanı almış ve DR’si olmayan DM’li hastalar ile sağlıklı kontrol grubu dahil edildi. Olguların Spectral-Domain optik kohe­rens tomografi (spektralis OKT cihazı ile EDI modunda (enhanced depth imaging- artırılmış derinlik görüntüleme­si horizontal düzlemde taraması yapıldı. Alınan görün­tülerden fovea merkezinden, fovea merkezine 1000 μm temporal ve nazalden koroid kalınlıkları ölçümü yapıldı. Ayrıca aynı cihazla pRSLT kalınlık ölçümü yapıldı. Bulgular: Çalışmaya DR’si olmayan 28 yeni tanılı DM hastasının 28 gözü ile 28 kontrol grubunun 28 gözü da­hil edildi. Yaş, cinsiyet, sferik ekivalan, düzeltilmiş en iyi görme keskinliği, göz içi basıncı ve aksiyel uzunluk de­ğerlerinde gruplar arasında anlamlı farklılık saptanmadı. Subfoveal ve temporal alanda koroid kalınlığının yeni ta­nılı DM grubunda kontrol grubuna göre daha ince olduğu saptandı (sırasıyla p=0,04, p=0,006. pRNFL analizinde ise averaj, nazal ve temporal süperior kadranlar yeni tanılı DM grubunda kontrol grubuna göre anlamlı olarak daha ince bulundu. Diğer pRNFL kadranlarında anlamlı bir fark saptanmadı. Sonuç: Çalışmamızın verileri değerlendirildiğinde yeni tanılı DM’li hastalarda DR bulguları olmaksızın koroid ta­bakasında incelmenin yanında pRSLT’de bazı incelmele­rin (özellikle averaj, nazal ve temporal süperior kadranlar­da olabileceğini söylemek mümkün görünmektedir.

  5. Karabük İçin Dış Duvar Optimum Yalıtım Kalınlığının Enerji Tasarrufu Ve Hava Kirliliğine Etkileri / The Effect Of External Wall Optimum Insulation Thickness On Energy Saving And Air Pollution For Karabük

    Directory of Open Access Journals (Sweden)

    Ali Etem Gürel

    2012-12-01

    Full Text Available Bina dış duvarlarında yapılacak ısı yalıtım uygulamaları, yakıt tüketimini düşürerek ekonomik kazanç sağlamanın yanında, fosil kaynaklı yakıt kullanımından kaynaklanan ve hava kirliliğine neden olan emisyonların düşürülmesinde de son derece etkilidir. Bu çalışmada Karabük’te kömür ve doğalgaz kullanımında dış duvar optimum yalıtım kalınlığı tespitinin ekonomik ve çevresel analizi yapılmıştır. Çalışmanın ekonomik boyutu, yaşam döngüsü maliyet analizine (LCCA dayanan P1-P2 yöntemi ile gerçekleştirilmiştir. Çalışmanın sonuçları, yakıt olarak kömür kullanıldığında optimum yalıtım kalınlığı ve enerji tasarrufunun sırasıyla 0.135 m ve 129.42 TL/m² olduğunu göstermiştir. Yakıt olarak doğalgaz kullanımında ise bu değerler sırasıyla 0.118 m ve 98.01 TL/m² olarak bulunmuştur. Optimum yalıtım kalınlığının hava kirliliğine olan etkileri incelendiğinde, yalıtımsız bina dış duvarında hesaplanan yıllık yakıt tüketimi, CO2 ve SO2 emisyonlarının yakıt tipine bağlı olarak optimum yalıtım kalınlığı noktasında %86’ya kadar azaldığı hesaplanmıştır. The Effect Of External Wall Optimum Insulation Thickness On Energy Saving And Air Pollution For Karabük Heat insulation applications carried out on external walls of building provides energy saving by decreasing fuel consumption and also quite important in decreasing emission which results from fossil-based fuel usage and causes air pollution. In this study, economic and environmental analyses were done for determination of external wall optimum thickness in using coal and natural gas usage in Karabük. Economic extent of the study was done with P1-P2 method which is based on life cycle cost analysis (LCCA. The results show that optimum insulation thickness and energy saving are 0.134 m and 117.14 TL/m² respectively when coal is used as a fuel. These values are 0.116 m and 88.39 TL

  6. 17. Yüzyıl Azerbaycan Sahasında Yazılan Hikayat Adlı Eserdeki Ünlü Uyumları Üzerine Bir İnceleme A Study On Vowel Harmony In Written Work Named Hikáyát In Azerbaijani Field In Seventeenth Century

    Directory of Open Access Journals (Sweden)

    Meltem GÜL

    2013-07-01

    Full Text Available When the sources examined explaining the development processof vowel harmony in Turkish, 17 century is seen as a dark period. Dueto the alphabet in Arabic script has a lack of conveying Turkishlanguage sounds generally researches were carried out on texttranscriptions which were written by foreign researchers. Althoughsome of the problems in themselves contain the texts of thesetranscription is very valuable for the history of Turkish sources. In thisstudy, 17 century vowel harmonies examined on Hikāyā t as a sampleand the features of period compared.Firstly; it has been found that which affixes impair vowel harmonyin the text. In order to represent the measurement in contradictions ofharmony, it has been analysed under different titles such as lexical itemroot, contradictions in phrase and contradictions in appendix.Apart form that; it has been observed precisely whether there isbackness harmony or not, In addition, The most important events of thesevententh century the sound was shown how the text of the lipharmony in Hikāyāt text. It has been established what is measurementin contradictions of harmony. It has been revealed if there is a usage ofregular or not in terms of flattening.The sevententh century of middle Ottoman period is evaluated asa transition period. It has been established whether there are featuresof transition perion precisely or not about wovel harmony in text andalso established how appendix is used generally.In addition, with this work written in Azerbaijani field the effectsof vowel harmony on Azerbaijani reflecting the additional usesdetermined and the different language characteristics betweenAzerbaijani Turkic and Turkey Turkish put forward. This article willcontribute to clarify 17th century Turkish on which there is very limitedresearch. Türkçenin ünlü uyumu ile ilgili gelişim sürecini anlatan kaynaklara bakıldığında 17. yüzyıl karanlık bir dönem olarak görülmektedir. Arap harfli alfabenin T

  7. Synthesis and characterization of the cubic coordination cluster [CoIII6CoII2(IBT)] (H 3IBT = 4,5-bis(tetrazol-5-yl)imidazole)

    Science.gov (United States)

    Dincă, Mircea; Harris, T. David; Iavarone, Anthony T.; Long, Jeffrey R.

    2008-11-01

    A self-assembly reaction between the ditopic ligand 4,5-bis(tetrazol-5-yl)imidazole (H 3IBT) and cobalt(II) chloride in basic aqueous medium afforded the mixed-valence molecular species (NBu)14[CoIII6CoII2(IBT)12]·22HO ( 1). X-ray analysis of 1 revealed a cubic arrangement of six trivalent and two divalent cobalt ions, with the latter situated on opposing vertices along the cube diagonal. The cubic coordination cluster was further characterized by cyclic voltammetry, mass spectrometry, and magnetic measurements.

  8. 3l1rhiral ~nlIrnaL

    African Journals Online (AJOL)

    nearby landscape with the subtlety of an artillery barrage." In this review recent advances in neutrophil p~siology and function, as well as mechanisms of inflammation-related tissue injury and carcinogenesis, are highlighted. Neutrophil production. About 55 - 60% of bone marrow is dedicated to the production of one cell ...

  9. Stofmisbrugsbehandling blandt grønlændere i Danmark

    DEFF Research Database (Denmark)

    Baviskar, Siddhartha

    2016-01-01

    , nationalitet) - Demografiske og socioøkonomiske karakteristika (fx skole og erhvervsuddannelse, hovedindtægtskilde, boligsituation, civilstatus, børn) - Hvilke stoffer der indtages (både hovedstoffer, fx hash, metadon, heroin, amfetamin og kokain, og sidestoffer såsom alkohol) - Hvor hyppigt og hvordan...

  10. Computed tomography in emphysematous pyelonephritis | Ünlüer ...

    African Journals Online (AJOL)

    Right nephrectomy was recommended to the patient with intravenous antibiotics and drainage. Several classification systems have been proposed to correlate imaging findings with subsequent prognosis and management in patients with emphysematous pyelonephritis. The mildest forms are confined to collecting system ...

  11. 3-D Animation, NL Editing & Special Effects Software Lab

    Data.gov (United States)

    Federal Laboratory Consortium — The Visual Effects Team of the Indirect Fire Division is a team of highly skilled people with specialized training and experience in Multimedia Production. Utilizing...

  12. 3l1rhiral ~nlIrnaL

    African Journals Online (AJOL)

    Neutrophil granules contain a large family of over 20 enzymes, but 4 proteolytic enzymes, the neutral serine proteases, elastase and proteinase 3, and the 2 metalloproteinases, collagenase and gelatinase, seem to have the greatest potential to act as mediators of tissue injury.' These proteases are released extracellularly ...

  13. Katilini Yaratan Annelik: Elif Şafak'ın "İskender" Adlı Romanından Yola Çıkarak Türkiye'de Kadınlık Ve Erkeklik Rollerine Dair Bir Sorgulama Motherhood Creating Its Killer: Based On Elif Shafak's Novel "Alexander" Questioning The Femininity And Masculinity In Turkey

    Directory of Open Access Journals (Sweden)

    İlknur MEŞE

    2013-03-01

    Full Text Available Elif Shafak‟s novel “Alexander” holds many references tofemininity and masculinity in the context of the „purity‟ of woman and„honor‟ of man, which still exist in Turkey. On the cover of the book, thewriter poses in man‟s suit which tells us that it is woman –especiallymothers- who prepares man to the appropriate masculinity. Theinequality between man and woman has been built culturally ratherthan a natural result created by biological differences. The concept ofmasculinity has been shaped by political, ideological, and marketorientedinterests. In this sense, masculinity gained hard meanings likemind, power, will, achievement, activity, committing violence, actingindependently, and knowing to rule the others. However, the concept offemininity - having the reverse situation- has soft meanings likecompassion, pity, conscience, peaceful, passivity, and sensuality.Woman has tried to negotiate her secondary position by aspiringthe power of man. In this sense, we can assess woman‟s wish for a malechild as a wish of legitimate power. Her wish of compensating herhelplessness with the power attributed to man has no benefit otherthan creating anothervictimhood. Femininity and its repercussionmotherhood are something produced down the generations. More orless each new generation has been affected by this legacy. Both menand women will be able to get over this power cycle by questioning thecultural system and using the capacity of their subjectivity. Elif Şafak‟ın “İskender” adlı romanı, Türkiye‟de halen varlığınısürdüren, kadının „namusu‟ ve erkeğin „şerefi‟ üzerinden kadınlık veerkeklik rolleri tanımlamalarına dair çok göndermeler bulabileceğimizbir eser. Yazarın, kitabın kapağında bir erkek takım elbisesi içindeverdiği pozun bize anlattığı şey, tıpkı romanın başkahramanı olanİskender gibi, erkekleri, kabullere uygun erkeklik rolüne hazırlayanlarınkadınlar -özellikle anneler

  14. Substrate and Lewis Acid Coordination Promote O-O Bond Cleavage of an Unreactive L2CuII2(O22-) Species to Form L2CuIII2(O)2 Cores with Enhanced Oxidative Reactivity.

    Science.gov (United States)

    Garcia-Bosch, Isaac; Cowley, Ryan E; Díaz, Daniel E; Peterson, Ryan L; Solomon, Edward I; Karlin, Kenneth D

    2017-03-01

    Copper-dependent metalloenzymes are widespread throughout metabolic pathways, coupling the reduction of O 2 with the oxidation of organic substrates. Small-molecule synthetic analogs are useful platforms to generate L/Cu/O 2 species that reproduce the structural, spectroscopic, and reactive properties of some copper-/O 2 -dependent enzymes. Landmark studies have shown that the conversion between dicopper(II)-peroxo species (L 2 Cu II 2 (O 2 2- ) either side-on peroxo, S P, or end-on trans-peroxo, T P) and dicopper(III)-bis(μ-oxo) (L 2 Cu III 2 (O 2- ) 2 : O) can be controlled through ligand design, reaction conditions (temperature, solvent, and counteranion), or substrate coordination. We recently published ( J. Am. Chem. Soc. 2012 , 134 , 8513 , DOI: 10.1021/ja300674m ) the crystal structure of an unusual S P species [(MeAN) 2 Cu II 2 (O 2 2- )] 2+ ( S P MeAN , MeAN: N-methyl-N,N-bis[3-(dimethylamino)propyl]amine) that featured an elongated O-O bond but did not lead to O-O cleavage or reactivity toward external substrates. Herein, we report that S P MeAN can be activated to generate O MeAN and perform the oxidation of external substrates by two complementary strategies: (i) coordination of substituted sodium phenolates to form the substrate-bound O MeAN -RPhO - species that leads to ortho-hydroxylation in a tyrosinase-like fashion and (ii) addition of stoichiometric amounts (1 or 2 equiv) of Lewis acids (LA's) to form an unprecedented series of O-type species (O MeAN -LA) able to oxidize C-H and O-H bonds. Spectroscopic, computational, and mechanistic studies emphasize the unique plasticity of the S P MeAN core, which combines the assembly of exogenous reagents in the primary (phenolates) and secondary (Lewis acids association to the MeAN ligand) coordination spheres with O-O cleavage. These findings are reminiscent of the strategy followed by several metalloproteins and highlight the possible implication of O-type species in copper-/dioxygen-dependent enzymes

  15. La scena dell’atto II.2 di «Aida» nell’allestimento scaligero del 1872 secondo Quinto Cenni, la disposizione scenica e il bozzetto di Girolamo Magnani

    Directory of Open Access Journals (Sweden)

    Paola Camponovo

    2016-12-01

    Full Text Available Oggetto di questo contributo è il primo allestimento italiano dell’Aida di Giuseppe Verdi (Teatro alla Scala, febbraio 1872. Ho selezionato un unico episodio dell’opera, l’atto II.2, la celebre scena del trionfo, per analizzare il modo in cui ci è stata tramandata dalle fonti, concentrandomi su tre testimonianze di natura visiva: due ben note – trattandosi del tipo di documenti generalmente utilizzati per lo studio delle messinscene storiche – che sono il bozzetto corrispondente di Girolamo Magnani e la disposizione scenica dell’opera redatta da Giulio Ricordi; la terza, mai studiata, è un’incisione di Quinto Cenni – Atto II, Scena II, dell’Opera «Aida» – pubblicata sul settimanale «Emporio pittoresco - Illustrazione universale» mentre le recite dell’opera erano ancora in corso. Attraverso queste tre fonti, mi concentrerò sull’analisi delle modalità e varianti con cui lo stesso identico evento è stato testualizzato, affrontando il problema della loro affidabilità, dal punto di vista di un ipotetico tentativo di ricostruzione della messinscena originale.

  16. The botrydial biosynthetic gene cluster of Botrytis cinerea displays a bipartite genomic structure and is positively regulated by the putative Zn(II)2Cys6 transcription factor BcBot6.

    Science.gov (United States)

    Porquier, Antoine; Morgant, Guillaume; Moraga, Javier; Dalmais, Bérengère; Luyten, Isabelle; Simon, Adeline; Pradier, Jean-Marc; Amselem, Joëlle; Collado, Isidro González; Viaud, Muriel

    2016-11-01

    Botrydial (BOT) is a non-host specific phytotoxin produced by the polyphagous phytopathogenic fungus Botrytis cinerea. The genomic region of the BOT biosynthetic gene cluster was investigated and revealed two additional genes named Bcbot6 and Bcbot7. Analysis revealed that the G+C/A+T-equilibrated regions that contain the Bcbot genes alternate with A+T-rich regions made of relics of transposable elements that have undergone repeat-induced point mutations (RIP). Furthermore, BcBot6, a Zn(II) 2 Cys 6 putative transcription factor was identified as a nuclear protein and the major positive regulator of BOT biosynthesis. In addition, the phenotype of the ΔBcbot6 mutant indicated that BcBot6 and therefore BOT are dispensable for the development, pathogenicity and response to abiotic stresses in the B. cinerea strain B05.10. Finally, our data revealed that B. pseudocinerea, that is also polyphagous and lives in sympatry with B. cinerea, lacks the ability to produce BOT. Identification of BcBot6 as the major regulator of BOT synthesis is the first step towards a comprehensive understanding of the complete regulation network of BOT synthesis and of its ecological role in the B. cinerea life cycle. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Meta Analiz Yaklaşımı ile Laktasyon Sırası ve Buzağılama Mevsiminin 305 Günlük Laktasyon Süt Verimi Üzerindeki Etki Büyüklüğünün Tahmini

    Directory of Open Access Journals (Sweden)

    Hande Küçükönder

    2014-08-01

    Full Text Available Bu çalışmada, Siyah Alaca ırkı ineklerde süt verimini etkileyen faktörlerden laktasyon sırası ve buzağılama mevsimin etkisi meta analiz yöntemi ile incelenmiştir. Meta analiz aynı amaca yönelik olarak başka araştırıcılar tarafından yapılmış olan çalışmaların bir araya getirilerek yeniden değerlendirilmesini sağlayan istatistiksel bir tekniktir. Bu yöntem, çeşitli alanlarda yapılmış olan çalışmaların sonuçlarını birleştirir, özetler ve araştırıcılar arasında ortak bir yargının oluşturulmasında katkı sağlar. Bu sebeplerden ötürü, bu çalışmada 7 farklı araştırıcının çalışmaları meta analiz ile birleştirilmiş ve incelenen parametreler hakkında ortak bir bakış açısının yaratılması hedeflenmiştir. Ayrıca araştırmada etki büyüklüklerinin heterojenlik durumu Ki kare ve I2 test istatistikleri ile araştırılmış ve bu değerler sırasıyla ×^2=50,205 ve I2=%88 olarak bulunmuştur. Bundan dolayı çalışmaların birleştirilmesi için sabit etki modeli kullanılmamıştır. Araştırmada, söz konusu konuya ilişkin olarak araştırıcıların bulmuş oldukları çalışma sonuçları meta analitik tarama yöntemi ile taranmış meta analizde etki büyüklüğü ölçütü olan odds oranının (OR kullanılması ile birleştirilmiştir. Meta analiz sonucunda Odds oranı değeri 0,759 bulunmuş olup, bulunan etki düzeyi orta olarak tespit edilmiştir. Yapılan bu çalışmayla Siyah Alaca sığırlarda 305 günlük laktasyon süt verimi üzerinde, laktasyon sırasının yüksek süt verimi elde edilmesinde Yapmış olduğu katkı payının buzağılama mevsimine nazaran 0,759 kat daha fazla olduğu belirlenmiştir.

  18. Staff exchange with Spokane Intercollegiate Research and Technology Institute (SIRTI), final project report

    Energy Technology Data Exchange (ETDEWEB)

    Alexander, G.M.

    1994-12-01

    Staff exchanges, such as the one described in this report, are intended to facilitate communication and collaboration among scientists and engineers at Department of Energy (DOE) laboratories, in U.S. industry, and academia. Funding support for these exchanges is provided by the DOE, Office of Energy Research, Laboratory Technology Transfer Program. Funding levels for each exchange typically range from $20,000 to $40,000. The exchanges offer the opportunity for the laboratories to transfer technology and expertise to industry, gain a perspective on industry`s problems, and develop the basis for further cooperative efforts through Cooperative Research and Development Agreements (CRADAS) or other mechanisms.

  19. Final Environmental Assessment (EA) for Headquarters Building Construction and Main Gate Reconfiguration White Bluff, Spokane, Washington

    Science.gov (United States)

    2012-12-01

    occurs as runoff from precipitation events (rain) or melting (snow). Runoff occurs from impermeable or semi-permeable natural and human-made surfaces...networks. The primary paved roads and parking areas are constructed of asphaltic concrete pavement over a crushed rock base. New roads were recently

  20. Metropolitan Spokane Region Water Resources Study. Appendix H. Volume 1. Plan Formulation and Evaluation

    Science.gov (United States)

    1976-01-01

    main Perry Street Sewer. Fortunately the sewers here are deep and most basements have checkvalves. The Central Avenue area is especially hard hit by...degradation by septic tank drainfield leachate and other urban wastes. The projected need becomes more critical in proportion to shoreline development and...applied throughout namely, anaerobic digestion , vacuum filtration and truck haul to sanitary landfill. An exception is made where lagoon treatment is

  1. 75 FR 65516 - ASC Machine Tools, Inc., Spokane Valley, WA; Notice of Affirmative Determination Regarding...

    Science.gov (United States)

    2010-10-25

    ... August 30, 2010 (75 FR 52986). The workers produce custom-order metal cutting machinery used to form and cut metal, including assembled equipment, component parts of equipment, and spare parts. The negative... decreased aggregate imports of metal cutting equipment during the relevant period and that the subject firm...

  2. 77 FR 25742 - Notice of Inventory Completion: Northwest Museum of Arts & Culture, Spokane, WA; Correction

    Science.gov (United States)

    2012-05-01

    ... bear penis bones, 2 gravers, 13 perforated elk teeth, 2 abalone gorgets, 6 copper pendants, 5 worked... time of death or later as part of the death rite or ceremony. Pursuant to 25 U.S.C. 3001(2), there is a...

  3. 75 FR 58429 - Notice of Inventory Completion: Northwest Museum of Arts & Culture, Spokane, WA

    Science.gov (United States)

    2010-09-24

    ... bear penis bones, 2 gravers, 13 perforated elk teeth, 1 abalone gorget, 6 copper pendants, 5 worked... reasonably believed to have been placed with or near individual human remains at the time of death or later as part of the death rite or ceremony. Lastly, officials of the Northwest Museum of Arts & Culture...

  4. Criteria of Coverage, Novelty, Search Printout and User Effort in Evaluating the Quality of Literature Searches Bilgi Taramalarının Nitelik Açısından Değerlendirilmesinde Bütünlük (Kapsam, Yenilik, Tarama Çıktısı ve Kullanıcı Çabası Ölçütleri

    Directory of Open Access Journals (Sweden)

    Birgül Egeli

    1995-09-01

    Full Text Available In general terms, relevance is the basic criterion which designates the quality of literature searches. Users of searching services are principally interested in relevance, that is the number of relevant articles retrieved. However, relevance alone, in spite of its prime significance, does not satisfy the user needs in total. Users express some other needs in terms of quality. Such needs, which a searching service or system should meet, caused to originate some other quality criteria, namely the coverage, novelty, search printout and user effort. Besides relevance, tliese criteria are used to evaluate the performance and effectiveness of searching systems in terms of quality. The present study discusses the abovementioned criteria in detail. The functions of these criteria in designating the search effectiveness as well as their roles in search failures are stated. Some approaches and solutions aimingat the practicing searcfiers in particular are offered to minimize search failures as well. Bilgi taramalarının nitelik açısından başarısı, temelde onların anlamlılık yönünden başarılı olup olmadıkları ile belirlenir. Tarama hizmetinin kullanıcıları anlamlılığa en büyük önemi vermekle beraber, sadece anlamlı künyelere erişme ile yetinmemekte, nitelikle ilgili başka gereksinim ve beklentilerini de dile getirmektedirler. Söz konusu kullanıcı gereksinim ve beklentileri, bütünlük (kapsam, yenilik, tarama çıktısı ve kullanıcı çabası gibi nitelik ölçütlerinin ortaya çıkmasına neden olmuştur. Bu ölçütler, anlamlılık ölçütü ile birlikte, taramaların nitelik açısından değerlendirilmesinde kullanılır olmuşlardır. Bu makalede anlamlılık dışında kalan tüm nitelik ölçütleri, tarama başarısını belirleyen yönleriyle tartışılmıştır. Ölçütlerin tarama başarısızlıklarını da ortaya çıkarabilecekleri üzerinde durularak, bu başarısızlıkları en aza indirebilmek

  5. Türk Dili Edebiyatı ve Türkçe Öğretmeni Adaylarının Sözcük Dağarcıklarının Değerlendirilmesi ve Günlük Yaşamlarına Yansımaları Evaluation of Turkish Literature and Turkish Language Teaching Majors’ Vocabulary Knowledge and Its Effect on Their Daily Life

    Directory of Open Access Journals (Sweden)

    Fatma SUSAR KIRMIZI

    2012-12-01

    özcük kadar kendini ifade etme şansına sahiptir. Bu araştırmanın amacı, üniversite öğrencilerinin sözcük dağarcıklarının yeterliliğini değerlendirmek ve sözcük dağarcıklarının günlük yaşamlarını nasıl etkilediğini tespit etmektir. Bu çalışmada nitel ve nicel araştırma yöntemleri bir arada kullanılmıştır. Araştırma Denizli‟de, Pamukkale Üniversitesi, Fen-Edebiyat Fakültesi Türk Dili ve Edebiyatı ile Eğitim Fakültesi Türkçe Eğitimi Bölümlerinde, 3. ve 4. sınıflarda gerçekleştirilmiştir (n=204. Örneklemin belirlenmesinde nitel araştırmada sıkça başvurulan “kolay ulaşılabilir durum örneklemesinden” yararlanılmıştır. Öğrencilerin Cumhuriyet dönemi edebiyatına ilişkin sözcük dağarcığını belirlemek için beş metinden yararlanılmıştır. Metinlerde geçen ve öğrencilerin bilmesi gerektiği düşünülen sözcüklere ilişkin bir sözcük havuzu oluşturulmuş daha sonra öğrencilerin bu sözcüklerden ne kadarını bilip bilmediği belirlenmeye çalışılmıştır. Bunun dışında öğrencilerin sözcük dağarcıklarının günlük yaşamlarına etkilerini belirlemek için araştırmacılar tarafından geliştirilen “yarı yapılandırılmış görüşme formu” kullanılmıştır. Öğrencilerin görüşlerini içeren yazılı formlar nitel veri seti olarak değerlendirilmeye alınmıştır. Bu araştırma kapsamında öğrencilerin en çok bilemediği üç sözcük, şekva, müstevlî ve müsavattır. Genel olarak Eğitim Fakültesi öğrencileri sözcük dağarcığının statü kazandırmada etkili olduğunu ifade etmektedir. Öğrenciler öğrendikleri yeni sözcükleri şiir, düz yazı, sınavlar ya da yazı çalışmalarının farklı bir türünde hatta internet yazılarında bile kullanmaktadır.

  6. Horns Rev II, 2D-Model Tests

    DEFF Research Database (Denmark)

    Andersen, Thomas Lykke; Brorsen, Michael

    . The objective of the tests was to investigate the impact pressures generated on a horizontal platform and a cone platform for selected sea states calibrated by Lykke Andersen & Frigaard, 2006. The measurements should be used for assessment of slamming coefficients for the design of horizontal and cone...

  7. (Niet) vergeten te meten: De Nederlandstalige Wechsler Memory Scale-Vierde editie (WMS-IV-NL)

    NARCIS (Netherlands)

    Bouman, Z.; Hendriks, M.P.H.; Dek, J.; Kessels, R.P.C.; Aldenkamp, A.P.

    2015-01-01

    Internationaal is de Wechsler Memory Scale (WMS) een van de meest gebruikte geheugenbatterijen. De recentste versie, de Wechsler Memory Scale – Fourth Edition (WMS-IV; Wechsler, 2009), is recent bewerkt en genormeerd voor het gebruik in Nederland: de Nederlandse Wechsler Memory Scale – Vierde Editie

  8. Closing the life cycle of phosphorus in an urban food system: the case Almere (NL)

    NARCIS (Netherlands)

    Dijk, van W.; Jansma, J.E.; Sukkel, W.; Reuler, van H.; Vermeulen, T.; Visser, A.J.

    2017-01-01

    In order to explore the possibilities of a local food system and its effects on the nutrient cycle, a desk study was executed for the urban region Almere, a Dutch city located in the Flevo Polder with about 200,000 inhabitants. This desk study takes this urban perspective as starting point in the

  9. Fabrication of a cantilever-based microfluidic flow meter with nL min(-1) resolution

    DEFF Research Database (Denmark)

    Noeth, Nadine-Nicole; Keller, Stephan Sylvest; Boisen, Anja

    2011-01-01

    ). With this etch the cantilever structures are under-etched before they are released by tweezers and the release yield is enhanced from 41.5% to 84.0%. In a continuous flow mode, the deflection of the cantilevers is directly proportional to the flow rate. By tuning the design of the integrated grid (hole size...

  10. Adherence to dietary guidelines and cardiovascular disease risk in the EPIC-NL cohort

    NARCIS (Netherlands)

    Struijk, E.A.; May, A.M.; Wezenbeek, N.L.W.J.; Fransen, H.; Soedamah-Muthu, S.S.; Geelen, A.; Boer, J.; Schouw, van der Y.T.; Bueno de Mesquita, H.B.; Beulens, J.W.J.

    2014-01-01

    Background Global and national dietary guidelines have been created to lower chronic disease risk. The aim of this study was to assess whether greater adherence to the WHO guidelines (Healthy Diet Indicator (HDI)); the Dutch guidelines for a healthy diet (Dutch Healthy Diet-index (DHD-index)); and

  11. NL-aegne diplom näitab haridustaset / Lea Michelson

    Index Scriptorium Estoniae

    Michelson, Lea

    1999-01-01

    Rahvusvaheline töögrupp töötas välja dokumendi "Diploma Supplement", ingliskeelse kõrgkooli diplomiga kaasneva lisa informatsiooni andmiseks omandatud kvalifikatsiooni, eriala, õppekava, kasutatud hindamissüsteemi, õpingute jätkamise õiguse ja muu kohta

  12. Boundary|Time|Surface: Art and Geology Meet in Gros Morne National Park, NL, Canada

    Science.gov (United States)

    Lancaster, Sydney; Waldron, John

    2015-04-01

    Environmental Art works range in scope from major permanent interventions in the landscape to less intrusive, more ephemeral site-specific installations constructed of materials from the local environment. Despite this range of intervention, however, these works all share in a tradition of art making that situates the artwork in direct response to the surrounding landscape. Andy Goldsworthy and Richard Long, for example, both favour methods that combine elements of both sculpture and performance in the creation of non-permanent interventions in the landscape, and both rely upon photographic, text-based, or video documentation as the only lasting indication of the works' existence. Similarly, Earth Scientists are responsible for interventions in the landscape, both physical and conceptual. For example, in Earth science, the periods of the geologic timescale - Cambrian, Ordovician, Silurian, etc. - were established by 19th century pioneers of geology at a time when they were believed to represent natural chapters in Earth history. Since the mid-20th century, stratigraphers have attempted to resolve ambiguities in the original definitions by defining stratotypes: sections of continuously deposited strata where a single horizon is chosen as a boundary. One such international stratotype, marking the Cambrian-Ordovician boundary, is defined at Green Point in Gros Morne National Park, Newfoundland. Boundary|Time|Surface was an ephemeral sculptural installation work constructed in June 2014. The main installation work was a fence of 52 vertical driftwood poles, 2-3 m tall, positioned precisely along the boundary stratotype horizon at Green Point in Newfoundland. The fence extended across a 150 m wave-cut platform from sea cliffs to the low-water mark, separating Ordovician from Cambrian strata. The installation was constructed by hand (with volunteer assistance) on June 22, as the wave-cut platform was exposed by the falling tide. During the remainder of the tidal cycle, and the following days, we allowed the fence to be dismantled by wave action and the incoming flood tide. The cycle of construction and destruction was documented in video and with time-lapse still photography. This project provided an opportunity for viewers to contemplate the brevity of human experience relative to the enormity of time, and the fragile and arbitrary nature of human-defined boundaries of all types. Future exhibitions of the documentation of this work are envisaged, which will provide opportunities for the public to interact with still and video images of the work directly, both as aesthetic objects and as sources of information regarding the geological and socio-political history of the site.

  13. The mechanics of sustainable urban development : The case of Lanxmeer, Culemborg, NL

    NARCIS (Netherlands)

    Vernay, A.L.; Salcedo Rahola, T.B.; Ravesteijn, W.

    2010-01-01

    Sustainable urban development projects are initiated almost every day. They are the results of very dynamic processes during which a number of decisions have to be taken according to the local conditions. Eventually each project follows its own path. The aim of this paper is to gain insight in the

  14. Information on radionuclides on the Internet. http://www.tue.nl/sbd/nvsnucleair.htm

    International Nuclear Information System (INIS)

    Franken, Y.

    1997-01-01

    A selection from Internet information sources on the subjects of radiation protection, dosimetry and medical radiation applications are discussed. The article is also available through the Internet (see title) including links to the discussed sites

  15. NL-Netherlands: Court applies Google Spain: no right to be forgotten for convicted criminal

    NARCIS (Netherlands)

    Breemen, V.

    2014-01-01

    On 18 September 2014, the Amsterdam Court handed down the first national application of the EU Court of Justice’s Google Spain judgment. The case was initiated by a convicted criminal after Google had not fully granted his online removal requests. The court rejected the claim, but it should be noted

  16. Airborne EM, Lithology and in-situ Data Used for Quantizing Groundwater Salinity in Zeeland (NL)

    Science.gov (United States)

    Meyer, U.; Siemon, B.; van Baaren, E.; Dabekaussen, W.; Delsman, J. R.; Karaoulis, M.; Gunnink, J.; Pauw, P.; Vermaas, T.

    2017-12-01

    In a setting of predominantly saline surface waters in Zeeland, the Netherlands, the only available shallow fresh groundwater is present in the form of freshwater lenses floating on top of the saline groundwater. This fresh water is vital for agricultural, industrial, ecological, water conservation and drinking water functions. An essential first step for managing the usable water properly is to know the present spatial fresh-brackish-saline groundwater distribution. As traditional salinity monitoring is labor-intensive, airborne electromagnetics, which is fast and can cover large areas in short time, is an efficient alternative. A consortium of BGR, Deltares and TNO conducted FRESHEM Zeeland (FREsh Salt groundwater distribution by Helicopter ElectroMagnetic survey in the Province of Zeeland) in 2014-17. An area of more than 2000 square km was surveyed using BGR's helicopter-borne geophysical system totaling to about 9,600 line-km. The HEM data, after inversion to 2.5 Million resistivity-depth models for each of the three 1D inversion procedures applied (Marquardt single site, smooth and sharp laterally constrained inversion), served as base-line information for further interpretation. A probabilistic Monte Carlo approach combines HEM resistivities, 3D lithology model data (GeoTOP), laboratory results (formation factor and surface conductivity) and local in-situ groundwater measurements for the translation of resistivity to Chloride concentration. The resulting 3D voxel model enables stakeholders to implement spatial Chloride concentration in their groundwater models.

  17. FRESHEM - Fresh-saline groundwater distribution in Zeeland (NL) derived from airborne EM

    Science.gov (United States)

    Siemon, Bernhard; van Baaren, Esther; Dabekaussen, Willem; Delsman, Joost; Gunnik, Jan; Karaoulis, Marios; de Louw, Perry; Oude Essink, Gualbert; Pauw, Pieter; Steuer, Annika; Meyer, Uwe

    2017-04-01

    In a setting of predominantly saline surface waters, the availability of fresh water for agricultural purposes is not obvious in Zeeland, The Netherlands. Canals and ditches are mainly brackish to saline due to saline seepage, which originates from old marine deposits and salt-water transgressions during historical times. The only available fresh groundwater is present in the form of freshwater lenses floating on top of the saline groundwater. This fresh groundwater is vital for agricultural, industrial, ecological, water conservation and drinking water functions. An essential first step for managing this fresh groundwater properly is to know the present spatial fresh-brackish-saline groundwater distribution. As traditional salinity monitoring is labour-intensive, airborne electromagnetics (AEM), which is fast and can cover large areas in short time, is an efficient alternative. A consortium of BGR, Deltares and TNO started FRESHEM Zeeland (FREsh Salt groundwater distribution by Helicopter ElectroMagnetic survey in the Province of Zeeland) in October 2014. Within 3x2 weeks of the first project year, the entire area of about 2000 km2 was surveyed using BGR's helicopter-borne geophysical system totalling to about 10,000 line-km. The HEM datasets of 17 subareas were carefully processed using advanced BGR in-house software and inverted to 2.5 Million resistivity-depth models. Ground truthing demonstrated that the large-scale HEM results fit very well with small-scale ground EM data (ECPT). Based on this spatial resistivity distribution, a 3D voxel model for Chloride concentration was derived for the entire province taking into account geological model data (GeoTOP) for the lithology correction and local in-situ groundwater measurements for the translation of water conductivity to Chloride concentration. The 3D voxel model enables stakeholders to implement spatial Chloride concentration in their groundwater models.

  18. Agro Informatica beschikbaar via vias.nl : samenwerking met ARTIK Bibliotheek Wageningen UR

    NARCIS (Netherlands)

    Genderen, van R.A.

    2004-01-01

    Attendering op de totstandkoming van het Agro Informatica Archief met artikelen uit het tijdschrift Agro Informatica. Via dit Archief kan weer doorgeklikt worden naar het volledige artikelenbestand van ARTIK

  19. A capacity analysis of the railway line Rotterdam?Dordrecht (NL)

    NARCIS (Netherlands)

    Schouwenaars, M.C.J.

    2012-01-01

    Although the Dutch railway network is one of the busiest ones in Europe, it is still not completely future?proof; the limits of the current rail system are reached. In some cases major adaptions to the timetable require adjustments to the tracks themselves to come to a valid operating plan. Besides,

  20. Simulation of the Prokaryotic Cell Cycle at http://simon.bio.uva.nl/cellcycle/

    Directory of Open Access Journals (Sweden)

    Arieh Zaritsky

    2012-02-01

    Full Text Available The bacterial Cell Cycle is presented using the Simulation program CCSim, which employs four parameters related to time (inter-division τ, replication C, division D and size (mass at replication initiation Mi, sufficient to describe and compare bacterial cells under various conditions. The parameter values can be altered and the effects of the alterations can be seen. CCSim is easy to use and presents the kinetics of cell growth in a digestible format. Replicating chromosomes and growing bacillary cells are coupled to parameters that affect the cell cycle and animated. It serves as an educational tool to teach bacteriology and to compare experimental observations with the model best describing cell growth thus improve our understanding of regulatory mechanisms. Examples are displayed of transitions between known physiological states that are consistent with experimental results, including one that explains strange observations. The program predicts enhanced division frequencies after a period of slow replication under thymine limitation if a minimal distance (Eclipse exists between successive replisomes, as observed. Missing features and ways to improve, extend and refine CCSim are proposed, for both single cells and random populations under steady-states of exponential growth and during well-defined transitions. Future improvements and extensions are proposed for single cells and populations.

  1. Simulation of the Prokaryotic Cell Cycle at simon.bio.uva.nl/cellcycle/

    Directory of Open Access Journals (Sweden)

    Charles E. Helmstetter

    2012-02-01

    Full Text Available The bacterial Cell Cycle is presented using the Simulation program CCSim, which employs four parameters related to time (inter-division τ, replication C, division D and size (mass at replication initiation Mi, sufficient to describe and compare bacterial cells under various conditions. The parameter values can be altered and the effects of the alterations can be seen. CCSim is easy to use and presents the kinetics of cell growth in a digestible format. Replicating chromosomes and growing bacillary cells are coupled to parameters that affect the cell cycle and animated. It serves as an educational tool to teach bacteriology and to compare experimental observations with the model best describing cell growth thus improve our understanding of regulatory mechanisms. Examples are displayed of transitions between known physiological states that are consistent with experimental results, including one that explains strange observations. The program predicts enhanced division frequencies after a period of slow replication under thymine limitation if a minimal distance (Eclipse exists between successive replisomes, as observed. Missing features and ways to improve, extend and refine CCSim are proposed, for both single cells and random populations under steady-states of exponential growth and during well-defined transitions. Future improvements and extensions are proposed for single cells and populations.

  2. 78 FR 2428 - Notice of Intent To Repatriate Cultural Items: Northwest Museum of Arts & Culture, Spokane, WA

    Science.gov (United States)

    2013-01-11

    ... appropriate Indian tribe, has determined that the cultural items meet the definition of unassociated funerary... the definition of unassociated funerary objects under 25 U.S.C. 3001. This notice is published as part... determinations in this notice. ] History and Description of the Cultural Items The funerary objects described...

  3. 75 FR 58424 - Notice of Intent to Repatriate Cultural Items: Northwest Museum of Arts & Culture, Spokane, WA

    Science.gov (United States)

    2010-09-24

    ... fragment, 5 glass beads, 9 perforated bear claws, 1 carved beaver tooth, 3 copper bells, 1 lot of burial... placed with or near individual human remains at the time of death or later as part of the death rite or...

  4. 77 FR 25736 - Notice of Intent To Repatriate Cultural Items: Northwest Museum of Arts & Culture, Spokane, WA...

    Science.gov (United States)

    2012-05-01

    ... glass beads, 9 perforated bear claws, 1 carved beaver tooth, 3 copper bells, 1 lot of burial fill, 22... remains at the time of death or later as part of the death rite or ceremony and are believed, by a...

  5. 78 FR 7448 - Final Environmental Impact Statement for the Proposed Spokane Tribe of Indians West Plains Casino...

    Science.gov (United States)

    2013-02-01

    ... casino-resort facility, parking structure, site retail, commercial building, tribal cultural center, and..., Washington 99201. The FEIS is also available online at: http://www.westplainseis.com . To obtain a compact... respondents, will be available for public review at the BIA mailing address shown in the ADDRESSES section of...

  6. Development and demonstration of a method to monitor the effects of measures to reduce VOC emissions in the EU. LIFE 95/NL/A11/NL/365/ZHL [1996-1998] (Final Report )

    NARCIS (Netherlands)

    Keuken, M.P.; Oss, R.F. van

    1998-01-01

    In 1996, TNO was granted by the European Commission to carry out in the framework of the LIFE programme a project entitled "Development and dem-onstration of a method to monitor the effects of measures to reduce VOC emis-sions in the EU". An additional grant was supplied by the Dutch Ministry for

  7. y sl a p ev re n ra nl u ht iw m sy ru e n a o d u e s p yr et ra ra nl U

    African Journals Online (AJOL)

    :r o ht u a g ni d n o p s er ro. C .N .J .r. D ro tr o. K. ,y re gr u. S fo tn e m tr a p e. D. ,s e c n ei c. S ht la e. H fo e g ell o. C. ,yt is re vi n. U et at. S e u n e. B. ,e ta. tS e u n e. B. ,i dr u k a. M ai re gi. N . 0. 6. 2. 4. 9. 6. 0. 6. 0. 7. 4. 3. 2. + k u. o c. o o h ay. @ e st e ul a. :y ra m m u. S. nI .y ru jni g nit ar te n e p y b d es u ac er a yll a us.

  8. Influence of high-strain rate and temperature on the mechanical behavior of Nl-, Fe-, and Ti- based aluminides

    Energy Technology Data Exchange (ETDEWEB)

    Gray, G.T. III

    1996-09-01

    The majority of the strength characterization studies on ordered intermetallics have concentrated on the assessment of strength and work-hardening at conventional strain rates. Although the influence of strain rate on the structure/property relationships of pure nickel, iron, and titanium and a variety of their alloys have been extensively studied, the effect of strain rate on the stress-strain response of Ni-, Fe-, and Ti-based aluminides remains poorly understood. Dynamic constitutive behavior is however relevant to high speed impact performance of these materials such as during foreign object damage in aerospace applications, high-rate forging, and localized deformation behavior during machining. The influence of strain rate, varied between 0.001 and 10{sup 4} s{sup -1}, and temperatures, between 77 & 800K, on the compressive mechanical behavior of Ni{sub 3}A1, NiAl, Fe{sub 3}Al, Fe-40Al-0.1B, Ti-24Al-11Nb, and Ti-48Al-2Cr-2Nb will be presented. In this paper the influence of strain rate on the anomalous temperature dependency of the flow stresses in these aluminides will be reviewed and compared between aluminides. The rate sensitivity and work hardening of each aluminide will be discussed as a function of strain rate and temperature and contrasted to each other and to the values typical for their respective disordered base metals. 66 refs., 16 figs., 2 tabs.

  9. Clinical validation of the WMS-IV-NL brief cognitive status exam (BCSE) in older adults with MCI or dementia.

    Science.gov (United States)

    Bouman, Zita; Hendriks, Marc P H; Aldenkamp, Albert P; Kessels, Roy P C

    2014-07-31

    ABSTRACT Background: The Brief Cognitive Status Exam (BCSE) is a new, optional subtest of the Wechsler Memory Scale-IV (WMS-IV) developed for rapid detection of cognitive deficits. We examined the clinical validation of the Dutch version of the BCSE in older adults with mild cognitive impairment (MCI) or dementia, comparing it to the Mini-Mental State Examination (MMSE). Method: BCSE and MMSE were administered in 39 older adults with MCI, 51 with dementia and 96 matched healthy controls. Results: Our results show that the BCSE is a valid screening instrument, with psychometric properties similar to the widely used MMSE. High correlations were found between the BCSE and MMSE (r = 0.79, n = 183, p < 0.001). Furthermore, a BCSE cut-off score ≤ 42 revealed a sensitivity of 96% a specificity of 92%, a positive predictive value of 86% and a negative predictive value of 97%, whereas the MMSE cut-off score of ≤ 24 showed values of 84%, 96%, 91%, and 92%, respectively. Sensitivity, specificity, positive and negative predictive values to detect MCI compared to controls was 81%, 80%, 61%, and 92%, respectively, on the BCSE, with a cut-off score of ≤ 46, and 84%, 76%, 57%, and 92%, respectively, on the MMSE, with a cut-off score of ≤ 27. Conclusions: The Dutch version of the BCSE is a clinically valid screening instrument for the detection of cognitive impairment in patients with dementia. Nevertheless, for distinguishing older adults with MCI from healthy controls both the BCSE and MMSE have limitations.

  10. DCE’s kommentarer vedr. markedsførings-anmeldelsen: EFSA-GMO-NL-2012-107 (MON810-pollen)

    DEFF Research Database (Denmark)

    Kjellsson, Gøsta; Strandberg, Morten Tune

    2012-01-01

    Markedsføringsanmeldelsen omhandler import og anvendelse af MON810-pollen direkte i fødemidler eller til videreforarbejdning til fødemidler (Anmeldelsen part 1 og 2.). Der indgår således ikke dyrkning eller foderanvendelse. Risikoen for spredningen af pollen ud i naturen, ved transportulykker og ...

  11. Fortsat tuberkuloseproblemer blandt danskere og grønlændere i Danmark og behov for styrket kontrol

    DEFF Research Database (Denmark)

    Lillebæk, Troels; Andersen, Ase Bengård; Seersholm, Niels Jørgen

    2012-01-01

    Active transmission of Mycobacterium tuberculosis (Mt) continues at surprisingly high rates in Denmark. The transmission is particularly observed in specific high risk segments of the population with social problems such as homelessness, alcohol, and/or drug abuse. The patients are infected...... with the "Danish Cluster 2" Mt outbreak strain, and the transmission is attributed to delayed diagnosis. This situation demands increased focus on early tuberculosis diagnosis, control of transmission, and improved actions calls for prioritising the prevention and control of tuberculosis politically...

  12. Metalogenic study of the uraniferous ore deposit at La Coma, Municipio of General Bravo, N.L. Mexico

    International Nuclear Information System (INIS)

    Ferriz D, H.

    1977-01-01

    The uraniferous ore deposit at la Coma is located in a sandy-clayish sequence of the cold formation (non marine member) of the middle oligocene under peneconcordant lenses within a sandy body, situated on the North flank of a microdelta formed by small streams which ran from West to East. The metalogenic study of this ore deposit, permits us to establish mineralization controls and guides for the optimization of the uranium prospecting in the miogeoclinical of the Gulf of Mexico setting. The study was carried out on the basis of sedimentalogic and metalogenic criteria, and it was found that the mineralization process seems to be related to the formation and filling of a paleochannel which cut the microdelta permeable beds. The uraniferous solutions migrated through the conglomeratic filling of the paleochannel and reached this way the permeable horizons of the microdelta, where they infiltrated adopting a pattern like an apron. In the sites where the solutions reached sandy lenses rich in organic matter, the soluble compounds containing the uranium suffered a decomposition with the consequent absorption of the uranium by the organic matter, due to the decrease of the pH value. In conclusion, the favorableness of the environment for mineralization is defined by the convergence of the described paleo-geomorphologic elements. (author)

  13. Primary standards for measuring flow rates from 100 nl/min to 1 ml/min - gravimetric principle.

    Science.gov (United States)

    Bissig, Hugo; Petter, Harm Tido; Lucas, Peter; Batista, Elsa; Filipe, Eduarda; Almeida, Nelson; Ribeiro, Luis Filipe; Gala, João; Martins, Rui; Savanier, Benoit; Ogheard, Florestan; Niemann, Anders Koustrup; Lötters, Joost; Sparreboom, Wouter

    2015-08-01

    Microflow and nanoflow rate calibrations are important in several applications such as liquid chromatography, (scaled-down) process technology, and special health-care applications. However, traceability in the microflow and nanoflow range does not go below 16 μl/min in Europe. Furthermore, the European metrology organization EURAMET did not yet validate this traceability by means of an intercomparison between different National Metrology Institutes (NMIs). The NMIs METAS, Centre Technique des Industries Aérauliques et Thermiques, IPQ, Danish Technological Institute, and VSL have therefore developed and validated primary standards to cover the flow rate range from 0.1 μl/min to at least 1 ml/min. In this article, we describe the different designs and methods of the primary standards of the gravimetric principle and the results obtained at the intercomparison for the upper flow rate range for the various NMIs and Bronkhorst High-Tech, the manufacturer of the transfer standards used.

  14. Adherence to the WHO's Healthy Diet Indicator and Overall Cancer Risk in the EPIC-NL Cohort

    NARCIS (Netherlands)

    Berentzen, N.E.; Beulens, J.W.; Hoevenaar-Blom, M.P.; Kampman, E.; Bueno-de-Mesquita, H.B.; Romaguera-Bosch, D.; Peeters, P.H.M.; May, A.M.

    2013-01-01

    Background: A healthy dietary pattern defined by international recommendations of the World Health Organisation (WHO) has been shown to reduce overall mortality risk. It is unknown whether this healthy dietary pattern is associated with overall cancer incidence. Design: In total 35,355 men and women

  15. The Dutch version of the Oral Health Impact Profile (OHIP-NL): translation, reliability and construct validity

    NARCIS (Netherlands)

    van der Meulen, M.J.; John, M.T.; Naeije, M.; Lobbezoo, F.

    2008-01-01

    Background The purpose of this study was to make a cross-culturally adapted, Dutch version of the Oral Health Impact Profile (OHIP), a 49-item questionnaire measuring oral health-related quality of life, and to examine its psychometric properties. Methods The original English version of the OHIP was

  16. Breaking down "Healthism": Barriers to Health and Fitness as Identified by Immigrant Youth in St. John's, NL, Canada

    Science.gov (United States)

    Shea, Jennifer M.; Beausoleil, Natalie

    2012-01-01

    In this article, we challenge dominant health and fitness discourses which stress individual responsibility in the attainment of these statuses. We examine the results of an empirical study exploring how a group of 15 Canadian immigrant youth, aged 12-17, discursively construct notions of health and fitness. Qualitative data were collected through…

  17. Territorial cohesion through cross-border landscape policy? The European case of the Three Countries Park (BE-NL-DE

    Directory of Open Access Journals (Sweden)

    Brüll Anja

    2017-10-01

    Full Text Available Landscapes can be understood as socialecological systems under constant change. In Europe various territorial dynamics pose persistent challenges to maintaining diverse landscapes both as European heritage and in their capacity to provide vital functions and services. Concurrently, under the competence of cohesion policy, the EU is attempting to improve policy making by better policy coordination and respecting regional specifics. This paper explores the question how a policy dedicated to landscape can help to handle territorial change and support territorial cohesion. It presents results and performances of the ESPON applied research study LP3LP: (1 a common landscape policy for the Three Countries Park, across the Dutch, German and Belgium borders, including a spatial landscape vision, a governance proposal of adaptive landscape management, and thematic strategies dealing with green infrastructure, cultural heritage, complementary biomass and quality production; (2 recommendations at the EU level. In discussing the significance of a landscape approach for EU policy,three dimensions of landscape are linked withimportant aspects of territorial cohesion: ‘landscape as asset’ addressing natural-cultural territorial capital as an indigenous base forsmart, sustainable, and inclusivedevelopment;‘landscape as place’ stressing the relevance of landscape for place-based policies; and ‘landscape as common ground’ highlighting its potential for horizontal, vertical, and territorial integration.

  18. Radio Frequency Performance Prediction in the North Sea: Analysis of the U.S.-NL Phase 1 Campaign

    Science.gov (United States)

    2016-09-01

    in this report is a testament to the quality of the state -of- the- art modeling capabilities in these [technical] areas for naval operational... States Government and therefore is not copyrighted. This work may be copied and disseminated without restriction. The citation of trade names and names...Netherlands Ministry of Defense (MoD). The objective of the CWP effort is to enhance radar modeling to enable improved situational awareness of the detection

  19. Fortsat tuberkuloseproblemer blandt danskere og grønlændere i Danmark og behov for styrket kontrol

    DEFF Research Database (Denmark)

    Lillebæk, Troels; Andersen, Ase Bengård; Seersholm, Niels Jørgen

    2012-01-01

    Active transmission of Mycobacterium tuberculosis (Mt) continues at surprisingly high rates in Denmark. The transmission is particularly observed in specific high risk segments of the population with social problems such as homelessness, alcohol, and/or drug abuse. The patients are infected...

  20. The development of divertor and first wall armour parts at JAERI, Sandia N.L. and KFA Juelich

    International Nuclear Information System (INIS)

    Akiba, M.; Bolt, H.; Watson, R.; Kneringer, G.; Linke, J.

    1991-01-01

    The development of new armour materials, and fabrication and testings of the divertor and first wall mock-ups have worldwidely been carried out during the Conceptual Design Activites (CDA) of ITER. This paper is a review of the activities on the divertor and first wall armour components which has been performed by JAERI, Sandia National Laboratory, and KFA Juelich. The design requirements have instantly been reflected in material development. For instance, carbon fiber composites (CFCs) have already been developed to have a thermal conductivity as high as copper at room temperature. Further modification of CFC's has been made. Based on the extensive progress in armour materials, the fabrication and testings of mock-ups have been started. Divertor mock-ups which are able to endure a stationary heat flux of 8 to 15 MW/m 2 have already been developed. Some new high heat flux test facilities have been constructed and are able to simulate a heat load of plasma disruption. Extensive understanding on disruption erosion of the armour materials has been obtained by experiments with these facilities. Some mock-up tests and disruption simulating tests have been performed under international collaboration. (orig.)

  1. A clinical prediction rule for detecting major depressive disorder in primary care : the PREDICT-NL study

    NARCIS (Netherlands)

    Zuithoff, Nicolaas P A; Vergouwe, Yvonne; King, Michael; Nazareth, Irwin; Hak, Eelko; Moons, Karel G M; Geerlings, Mirjam I

    BACKGROUND: Major depressive disorder often remains unrecognized in primary care. OBJECTIVE: Development of a clinical prediction rule using easily obtainable predictors for major depressive disorder in primary care patients. METHODS: A total of 1046 subjects, aged 18-65 years, were included from

  2. Pazarda Rekabetçi Üstünlük Aracı Olarak Hedef Maliyetleme

    OpenAIRE

    AKSOYLU, Semra; DURSUN, Yunus

    2001-01-01

    Günümüz işletmeleri hızla değişen bir çevrede faaliyetlerini sürdürmektedir. Bir işletmenin böylesi bir çevrede varlığını sürdürmesi ve büyümesi, diğerfaktörlerin yanında, hedef pazarının beklediği fiyat ve kalitede özgün ve yeni ürünleri üretme ve pazara sunma kapasitesine bağlıdır. Hedef pazarın kalite ve fiyatbeklentisini karşılayan ürünleri üretmek ve pazara sunmak için kullanılan araçlardan birisi de hedef maliyetleme yöntemidir. Bu yöntem, günümüzün rekabetçi çevresinde işletmenin rekab...

  3. The population-based prescription database IADB.nl : its development, usefulness in outcomes research and challenges

    NARCIS (Netherlands)

    Visser, Sipke T; Schuiling-Veninga, Nynke; Bos, Jens H J; de Jong-van den Berg, Lolkje T W; Postma, Maarten J

    Research databases with large numbers of prescriptions in observational settings can provide valuable information in addition to the initial randomized controlled trials. This paper reports on the development of prescription database IADB, formerly known as InterAction Database. IADB contains

  4. Spectroscopic investigation of new water soluble Mn(II)(2) and Mg(II)(2) complexes for the substrate binding models of xylose/glucose isomerases.

    Science.gov (United States)

    Patra, Ayan; Bera, Manindranath

    2014-01-30

    In methanol, the reaction of stoichiometric amounts of Mn(OAc)(2)·4H(2)O and the ligand H(3)hpnbpda [H(3)hpnbpda=N,N'-bis(2-pyridylmethyl)-2-hydroxy-1,3-propanediamine-N,N'-diacetic acid] in the presence of NaOH, afforded a new water soluble dinuclear manganese(II) complex, [Mn2(hpnbpda)(μ-OAc)] (1). Similarly, the reaction of Mg(OAc)(2)·4H(2)O and the ligand H3hpnbpda in the presence of NaOH, in methanol, yielded a new water soluble dinuclear magnesium(II) complex, [Mg2(hpnbpda)(μ-OAc)(H2O)2] (2). DFT calculations have been performed for the structural optimization of complexes 1 and 2. The DFT optimized structure of complex 1 shows that two manganese(II) centers are in a distorted square pyramidal geometry, whereas the DFT optimized structure of complex 2 reveals that two magnesium(II) centers adopt a six-coordinate distorted octahedral geometry. To understand the mode of substrate binding and the mechanistic details of the active site metals in xylose/glucose isomerases (XGI), we have investigated the binding interactions of biologically important monosaccharides d-glucose and d-xylose with complexes 1 and 2, in aqueous alkaline solution by a combined approach of FTIR, UV-vis, fluorescence, and (13)C NMR spectroscopic techniques. Fluorescence spectra show the binding-induced gradual decrease in emission of complexes 1 and 2 accompanied by a significant blue shift upon increasing the concentration of sugar substrates. The binding modes of d-glucose and d-xylose with complex 2 are indicated by their characteristic coordination induced shift (CIS) values in (13)C NMR spectra for C1 and C2 carbon atoms. Copyright © 2013 Elsevier Ltd. All rights reserved.

  5. Landslide conditions along the Ferry County highway parallelling Lake Roosevelt from Kettle Falls to the mouth of the Spokane River, Washington

    Science.gov (United States)

    Jones, Fred O.

    1954-01-01

    As part of the program of the U.S. Geological Survey, landslides are being studied in several localities in the United States. These studies are directed toward assembling criteria for recognition of landslides, classification, and cataloging of remedial or control methods that have been effective.  In the gorge of the Columbia Ricer in Washington, landslides of large magnitude have been active intermittently since the valley was first incised.  Closure of Grand Coulee Dam, with the consequent rise of water forming Franklin D. Roosevelt Lake, has introduced the factor of a rising and fluctuating water table that accentuates the incidence of landsliding.  This area was selected for study because of the magnitude of the landslides and the unknown but significant influence of a fluctuating water table.  Data resulting from the studies will be summarized in a final report.

  6. Crystal structure of aquatris(isonicotinamide-κNbis(thiocyanato-κNcobalt(II 2.5-hydrate

    Directory of Open Access Journals (Sweden)

    Tristan Neumann

    2016-09-01

    Full Text Available The asymmetric unit of the title compound, [Co(NCS2(C6H6N2O3(H2O]·2.5H2O, comprises one CoII cation, three isonicotinamide ligands, two thiocyanate anions, one aqua ligand and two water solvent molecules in general positions, as well as one water solvent molecule that is located on a twofold rotation axis. The CoII cations are octahedrally coordinated by two terminally N-bonded thiocyanate anions, one water molecule and three isonicotinamide ligands, each coordinating via the pyridine N atom. The discrete complexes are linked by intermolecular O—H...O, N—H...O and N—H...S hydrogen bonding into a three-dimensional network that contains cavities in which the solvent water molecules are located. The latter are linked by further O—H...O hydrogen bonds to the network. There are additional short contacts present in the crystal, indicative of weak C—H...S, C—H...O and C—H...N interactions.

  7. Thermal decomposition study and biological characterization of zinc(II) 2-chlorobenzoate complexes with bioactive ligands

    Czech Academy of Sciences Publication Activity Database

    Findoráková, L.; Györyová, K.; Hudecová, D.; Mudroňová, D.; Kovářová, Jana; Homzová, K.; Nour El-Dien, F. A.

    2013-01-01

    Roč. 111, č. 3 (2013), s. 1771-1781 ISSN 1388-6150. [Central and Eastern European Conference on Thermal Analysis and Calorimetry /1./ - CEEC-TAC1. Craiova, 07.09.2011-10.09.2011] Institutional research plan: CEZ:AV0Z40500505 Keywords : zinc * 2-chlorobenzoate * thermal Subject RIV: CD - Macromolecular Chemistry Impact factor: 2.206, year: 2013

  8. Synthesising highly reactive tin oxide using Tin(II2- ethylhexanoate polynucleation as precursor

    Directory of Open Access Journals (Sweden)

    Alejandra Montenegro Hernández

    2009-01-01

    Full Text Available Tin oxide is a widely used compound in technological applications, particularity as a catalyst, gas sensor and in making varistors, transparent conductors, electrocatalytic electrodes and photovoltaic cells. An ethylhexanoate tin salt, a carboxylic acid and poly-esterification were used for synthesising highly reactive tin oxide in the present study. Synthesis was controlled by Fourier transform infrared (FTIR spectroscopy and recording changes in viscosity. The tin oxide characteristics so obtained were determined using FTIR spectroscopy, X-ray diffraction (XRD and scanning electron microscopy (SEM. The SnO2 dust synthesised and heat-treated at 550°C yielded high density aggregates, having greater than 50 μm particle size. This result demonstrates the high reactivity of the ceramic powders synthesised here.

  9. Thermal hydraulics-II. 2. Benchmarking of the TRIO Two-Phase-Flow Module

    International Nuclear Information System (INIS)

    Helton, Donald; Kumbaro, Anela; Hassan, Yassin

    2001-01-01

    The Commissariat a l'Energie Atomique (CEA) is currently developing a two-phase-flow module for the Trio-U CFD computer program. Work in the area of advanced numerical technique application to two-phase flow is being carried out by the SYSCO division at the CEA Saclay center. Recently, this division implemented several advanced numerical solvers, including approximate Riemann solvers and flux vector splitting schemes. As a test of these new advances, several benchmark tests were executed. This paper describes the pertinent results of this study. The first benchmark problem was the Ransom faucet problem. This problem consists of a vertical column of water acting under the gravity force. The appeal of this problem is that it tests the program's handling of the body force term and it has an analytical solution. The Trio results [based on a two-fluid, two-dimensional (2-D) simulation] for this problem were very encouraging. The two-phase-flow module was able to reproduce the analytical velocity and void fraction profiles. A reasonable amount of numerical diffusion was observed, and the numerical solution converged to the analytical solution as the grid size was refined, as shown in Fig. 1. A second series of benchmark problems is concerned with the employment of a drag force term. In a first approach, we test the capability of the code to take account of this source term, using a flux scheme solution technique. For this test, a rectangular duct was utilized. As shown in Fig. 2, mesh refinement results in an approach to the analytical solution. Next, a convergent/divergent nozzle problem is proposed. The nozzle is characterized by a brief contraction section and a long expansion section. A two-phase, 2-D, non-condensing model is used in conjunction with the Rieman solver. Figure 3 shows a comparison of the pressure profile for the experimental case and for the values calculated by the TRIO U two-phase-flow module. Trio was able to handle the drag force term and reproduce the experimental pressure profile. However, based on the results obtained here, a more rigorous drag force model should be implemented. Based on these, and other benchmark cases, further work is being done in the development of the two-phase-flow module. To carry on this study, future work is planned to construct an analytical nozzle problem and to compare results between the two different solver types. (authors)

  10. Inadequate computer backup process resulting in data loss, US site. Annex II-2

    International Nuclear Information System (INIS)

    2008-01-01

    All the files on a computer should be transferred to a read/write CD during computer exchanges to ensure that files not identified by the user as necessary will be available once the computer has been sanitized. Users should be required to check that the files have been uploaded from the disk, to ensure that they are all present and accessible before former computer drives are sanitized. Computers destined for sanitizing should have all the information on them backed up on a read/write CD, reloaded onto the new computer and verified by the user before the computer is sanitized

  11. Comparative Evaluation Study of II2 O2 Mouthrinse in Gingivitis

    Directory of Open Access Journals (Sweden)

    Haghighati F

    1999-12-01

    Full Text Available Bacteria! plaque is an essential factor of gingival and periodontal disease."nThe ability of chemical piaque control agent to prevent plaque formation is well documented compare with"nother mechanical plaque removal methods. The purpose of this study was to compare clinical effects of"nShore choice mouth rinse (H2 O2, 0.1% with a placebo."nFollowing a period of 4 weeks, 20 subjects were allocated to two treatment groups."nDuring this period of time, they rinsed twice a day with either a placebo mouth rinse or the Shor choice."nPlaque Index (PI and bleeding on probing index (BOP were recorded three days after scaling and root"nplanning. These indecies were rechecked 2 and 4 weeks after rinsing the subject's mouth by mouth rinse and"nplacebo. Results indicated that although there were no significant differences between test and control"ngroups, a reduction of PI and BOP were found in different stages of this study."nThe clinical data obtained in this study are thus consistent with the previous data, however, care should be"ntaken to extrapolate these results.

  12. ;-L IN EDS ST NIGEEIF-Ii 2' iz- BERICK ULUSEGUN AKINBG',

    African Journals Online (AJOL)

    asymptomatic malaria among pregnant women are advocated. Malaria is reoogized as ... wastes ::.;;-;:: interventio necessitated this study. this hacund, this study sad at deternt the prevence of asymptomatic malaria in present women in Be :1: ii. City, Nigeria. Stay. The study ... anyzer [Sysmex Corporation, Kobe, japan]. 5 site.

  13. The nomenclature of the Athenian Artists of Dionysus in IG II2 1132-3

    DEFF Research Database (Denmark)

    Lech, Marcel Lysgaard

    2013-01-01

    In this article, I discuss the earliest nomenclature of the Athenian artists of Dionysus, which I will argue is not only unique among the overall evidence on Dionysiac artists available to us at this point, but also evinces a recognized political potential in the newly organized association of th...

  14. Thermal decomposition and antimicrobial activity of zinc(II) 2-bromobenzoates with organic ligands

    Czech Academy of Sciences Publication Activity Database

    Krajníková, A.; Györyová, K.; Hudecová, D.; Kovářová, Jana; Vargová, Z.

    2011-01-01

    Roč. 105, č. 2 (2011), s. 451-460 ISSN 1388-6150. [European Symposium on Thermal Analysis and Calorimetry /10./. Rotterdam, 22.08.2010-27.08.2010] Institutional research plan: CEZ:AV0Z40500505 Keywords : zinc 2-bromobenzoate * spectral properties * thermal behaviour Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.604, year: 2011

  15. Canned motor pumps at Heavy Water Project, Baroda [Paper No.: II-2

    International Nuclear Information System (INIS)

    Batra, R.K.; Waishampayan, S.G.

    1981-01-01

    Heavy Water Project, Baroda is having special canned motor pumps for pumping ammonia and potassium amide. These pumps work under a pressure of 640 kg/cm 2 and are lubricated and cooled by the same fluid. These pumps are having special bearings consisting of mating surfaces of tungsten carbine Vs ceramic or stellite Vs carbon depending upon application. The total number of such pumps installed in the plant is around 52. These pumps being installed in high pressure vessels working at a pressure of 640 kg/cm 2 have special maintenance problems and need special care during maintenance. Pumps once boxed up are completely out of reach for immediate maintenance if needed. The failure of these pumps may mean a down time of one to two months for the plant. Besides above, there are multistage barrel type ammonia pumps with 24 stages developing a pressure of 140 kg/cm 2 . All these equipments need special maintenance methods as the problems faced are varied and difficult to solve. This paper deals with general and unique type of problems faced on these pumps. (author)

  16. Ethylene oligomerization in metal-organic frameworks bearing nickel(ii) 2,2'-bipyridine complexes.

    Science.gov (United States)

    Gonzalez, Miguel I; Oktawiec, Julia; Long, Jeffrey R

    2017-09-08

    The metal-organic frameworks Zr 6 O 4 (OH) 4 (bpydc) 6 (1; bpydc 2- = 2,2'-bipyridine-5,5'-dicarboxylate) and Zr 6 O 4 (OH) 4 (bpydc) 0.84 (bpdc) 5.16 (2; bpdc 2- = biphenyl-4,4'-dicarboxylate) were readily metalated with Ni(DME)Br 2 (DME = dimethoxyethane) to produce the corresponding metalated frameworks 1(NiBr 2 ) 6 and 2(NiBr 2 ) 0.84 . Both nickel(ii)-containing frameworks catalyze the oligomerization of ethylene in the presence of Et 2 AlCl. In these systems, the pore environment around the active nickel sites significantly influences their selectivity for formation of oligomers over polymer. Specifically, the single-crystal structure of 1(NiBr 2 ) 5.64 reveals that surrounding metal-linker complexes enforce a steric environment on each nickel site that causes polymer formation to become favorable. Minimizing this steric congestion by isolating the nickel(ii) bipyridine complexes in the mixed-linker framework 2(NiBr 2 ) 0.84 markedly improves both the catalytic activity and selectivity for oligomers. Furthermore, both frameworks give product mixtures that are enriched in shorter olefins (C 4-10 ), leading to deviations from the expected Schulz-Flory distribution of oligomers. Although these deviations indicate possible pore confinement effects on selectivity, control experiments using the nickel-treated biphenyl framework Zr 6 O 4 (OH) 4 (bpdc) 6 (NiBr 2 ) 0.14 (3(NiBr 2 ) 0.14 ) reveal that they likely arise at least in part from the presence of nickel species that are not ligated by bipyridine within 1(NiBr 2 ) 5.64 and 2(NiBr 2 ) 0.84 .

  17. Development of a Hydrologic Characterization Technology for Fault Zones Phase II 2nd Report

    Energy Technology Data Exchange (ETDEWEB)

    Karasaki, Kenzi [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Doughty, Christine [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Gasperikova, Erika [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Peterson, John [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Conrad, Mark [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Cook, Paul [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Tiemi, Onishi [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2011-03-31

    This is the 2nd report on the three-year program of the 2nd phase of the NUMO-LBNL collaborative project: Development of Hydrologic Characterization Technology for Fault Zones under NUMO-DOE/LBNL collaboration agreement. As such, this report is a compendium of the results by Kiho et al. (2011) and those by LBNL.

  18. Draft of the EU regulation for the infrastructure for alternate fuels. Impact assessment for the Netherlands; Concept EU Richtlijn Uitrol Infrastructuur voor Alternatieve Brandstoffen. Impact Assessment voor NL

    Energy Technology Data Exchange (ETDEWEB)

    Weeda, M. [ECN Beleidsstudies, Petten (Netherlands)

    2013-08-15

    On 24 January 2013, the European Commission approved a proposal for a directive on the rollout of infrastructure for alternative fuels for transport. The directive mostly covers the charging infrastructure for electric vehicles; CNG, LNG and hydrogen refuelling stations for road traffic, and LNG bunker facilities for shipping. On assignment of the Dutch Ministry of Infrastructure and the Environment, ECN conducted an impact assessment of the proposal for the directive for the Dutch situation. The overall conclusion is that the estimates for the Netherlands in the framework of the directive with regard to the required infrastructure for alternative fuels and the investment amount reasonably concur with the government's objectives and the expectations of market parties. Given all uncertainties about numbers and exact costs, the conclusion is drawn that, until the end of 2020, an amount of about Meuro 400 will be needed for investments in the infrastructure for alternative fuels. However, this covers only a part of the investments related to the directive. To realise the objectives, applications for alternative fuels will need to be stimulated and the financial gap in exploiting infrastructures also needs to be financed. As it is difficult to determine beforehand which costs are involved, it is important to maintain flexibility in objectives for volume and realisation pace of the infrastructure for alternative fuels. In this respect, a result obligation to realise a certain volume of infrastructure before a set date, as envisaged by the directive, is not beneficial [Dutch] Op 24 januari 2013 heeft de Europese Commissie een voorstel voor een richtlijn goedgekeurd betreffende de uitrol van infrastructuur voor alternatieve brandstoffen voor transport. De richtlijn heeft vooral betrekking op oplaadinfrastructuur voor elektrische auto's; CNG, LNG en waterstoftankstations voor wegverkeer, en LNG bunkerfaciliteiten voor de scheepvaart. ECN heeft in opdracht van het Ministerie van Infrastructuur en Milieu een impact assessment gemaakt van het voorstel voor de richtlijn voor de Nederlandse situatie. Overall is de conclusie dat de inschattingen voor Nederland in het kader van de richtlijn over omvang van benodigde infrastructuur voor alternatieve brandstoffen en de hoogte van de investeringskosten redelijk goed overeenkomen met overheidsdoelstellingen en verwachtingen van marktpartijen hierover. Gegeven alle onzekerheden over aantallen en exacte kosten wordt geconcludeerd dat tot eind 2020 ordegrootte 400 Meuro nodig is voor investeringen in infrastructuur voor alternatieve brandstoffen. Dit is echter slechts een deel van de investeringen die samenhangen met de richtlijn. Realisatie van doelstellingen vergt ook stimulering van toepassingen voor alternatieve brandstoffen en financiering van de onrendabele top in de exploitatie van infrastructuren. Omdat kosten die hiermee samenhangen lastig op voorhand zijn te bepalen is het van belang om flexibiliteit te behouden in doelstellingen voor omvang en snelheid van realisatie van infrastructuur voor alternatieve brandstoffen. Een resultaatverplichting voor realisatie van een hoeveelheid infrastructuur voor een bepaalde datum zoals beoogd door de richtlijn is in dit opzicht niet gunstig.

  19. Validity and Reliability of the Dutch Version of the International Hip Outcome Tool (iHOT-12NL) in Patients With Disorders of the Hip

    NARCIS (Netherlands)

    Stevens, Martin; Van den Akker-Scheek, Inge; Ten Have, Bas; Adema, Marco; Giezen, Hilde; Reininga, Inge H. F.

    2015-01-01

    STUDY DESIGN: Clinical measurement. OBJECTIVES: To translate and culturally adapt the international Hip Outcome Tool (iHOT-12) into Dutch and to determine its validity and reliability. BACKGROUND: The iHOT-12 for measuring health-related quality of life and physical functioning in younger, active

  20. The important role of CRIS’s for registration and archiving of research data. The RDS-Project at Radboud University (NL) in cooperation with DANS.

    NARCIS (Netherlands)

    Simons, Ed; Jetten, Mijke; van Berchum, M.; Messelink, Maaike; Schoonbrood, Hans; Wittenberg, M.

    2016-01-01

    Optimal research data management and archiving is a key condition for progress in modern science and of vital importance from both the point of view of research as such as well as research policy and management. More specifically it is a conditio sine qua non for the realisation of Open Science and

  1. Identifying cardiovascular risk factor-related dietary patterns with reduced rank regression and random forest in the EPIC-NL cohort

    NARCIS (Netherlands)

    Biesbroek, Sander; Van Der A., Daphne L.; Brosens, Marinka C C; Beulens, Joline W J; Verschuren, W. M Monique; Van Der Schouw, Yvonne T.; Boer, Jolanda M A

    2015-01-01

    Background: Several methods are used to determine dietary patterns. Hybrid methods incorporate information on nutrient intake or biological factors to extract patterns relevant to disease etiology. Objective: We explore differences between patterns derived with 2 hybrid methods with those obtained

  2. Rational Design of Bacillus coagulans NL01 l-Arabinose Isomerase and Use of Its F279I Variant in d-Tagatose Production.

    Science.gov (United States)

    Zheng, Zhaojuan; Mei, Wending; Xia, Meijuan; He, Qin; Ouyang, Jia

    2017-06-14

    d-Tagatose is a prospective functional sweetener that can be produced by l-arabinose isomerase (AI) from d-galactose. To improve the activity of AI toward d-galactose, the AI of Bacillus coagulans was rationally designed on the basis of molecular modeling and docking. After alanine scanning and site-saturation mutagenesis, variant F279I that exhibited improved activity toward d-galactose was obtained. The optimal temperature and pH of F279I were determined to be 50 °C and 8.0, respectively. This variant possessed 1.4-fold catalytic efficiency compared with the wild-type (WT) enzyme. The recombinant Escherichia coli overexpressing F279I also showed obvious advantages over the WT in biotransformation. Under optimal conditions, 67.5 and 88.4 g L -1 d-tagatose could be produced from 150 and 250 g L -1 d-galactose, respectively, in 15 h. The biocatalyst constructed in this study presents a promising alternative for large-scale d-tagatose production.

  3. Validity of the New Lifestyles NL-1000 Accelerometer for Measuring Time Spent in Moderate-to-Vigorous Physical Activity in School Settings

    Science.gov (United States)

    McMinn, David; Rowe, David A.; Stark, Michelle; Nicol, Louise

    2010-01-01

    Current interest in promoting physical activity in the school environment necessitates an inexpensive, accurate method of measuring physical activity in such settings. Additionally, it is recognized that physical activity must be of at least moderate intensity in order to yield substantial health benefits. The purpose of the study, therefore, was…

  4. Visit the journal at http://www.elsevier.nl/locate/jnlnr/00212 Accretion and primary differentiation of the Earth: a personal journey

    Science.gov (United States)

    Drake, Michael J.

    2000-07-01

    The accretion of the Earth was a violent series of events dominated by the addition of objects one third to one tenth of the mass of the growing planet. During the later stages of accretion, these collisions deposited enough energy to at least partly melt the Earth, possibly multiple times. The result was an ocean of magma. Metal sank through this magma ocean and ponded at its base at roughly the depth of the base of the current upper mantle for some period of time before transiting diapirically through the lower mantle to the center of the planet. Metal appears to have equilibrated with silicate at the base of the magma ocean. The primitive atmosphere and ocean appear to have outgassed from the magma ocean. Core formation, magma ocean solidification, ocean and atmospheric outgassing were essentially complete by 4.45 Ga ago.

  5. NL-Alert : Na welk alarmbericht komt u in actie? Resultaten van een webbased experiment waarin de bevolking helpt effectieve berichten voor burgeralarmering te ontwikkelen

    NARCIS (Netherlands)

    Jagtman, H.M.; Sillem, S.; Ale, B.J.M.

    2012-01-01

    Dit rapport presenteert de resultaten van een experiment waarin 1082 mensen hun waardering gaven over alarmberichten rond incidenten bij het transport met gevaarlijke stoffen, bij installaties met gevaarlijke stoffen, voor natuurbranden en voor stroomstoringen. Het doel was inzicht te krijgen in de

  6. Elektron-Alüminyum Etkileşiminde Depolanan Enerjinin Hedef Kalınlığı ile Değişimi

    Directory of Open Access Journals (Sweden)

    Zehra Nur DEMİRCİ

    2014-07-01

    Full Text Available Accelerators, which are high technology, has been setup in a large number of facility in the world. The accelerated beams can be used in particle or nuclear physics experiment. Thickness of target, which used in production bremsstrahlung photon by accelerated electrons, is important. In this study, the variation of energy deposition with target thickness has been investigated due to interaction of 8 MeV energy accelerated electron beam with aluminum target at different thicknesses. Depending the target thickness of energy deposition on Al target has been simulated using FLUKA code. The energy deposition on the target has increased with increasing thickness of target material

  7. The use of English in job advertisments on the Dutch job site Monsterboard.nl and factors on which it depends

    NARCIS (Netherlands)

    Meurs, F. van; Korzilius, H.P.L.M.; Hollander, Adriënne den

    2006-01-01

    Previous studies on the factors that determine the use of English in product advertising and print-medium job advertisements in non-English-speaking countries have overwhelmingly analysed English in product advertising. Drawing on the reasons suggested in such studies, the present contribution

  8. Noot bij Afdeling Bestuursrechtspraak Raad van State, 21 januari 2015, nr. 201401598/1/V6, ECLI:NL:RVS:2015:102

    NARCIS (Netherlands)

    Oosterom-Staples, Helen

    2015-01-01

    Moet een wettelijke regeling die niet werd gehandhaafd op het moment waarop de stand still-verplichting in het Associatierecht EEG-Turkije voor Nederland in werking trad buiten toepassing worden gelaten en bij welke partij - de Staat of de Turkse burger - ligt de bewijslast dat die regeling in het

  9. Drug-use patterns of initially prescribed insulin detemir and insulin glargine in the Netherlands; A comparative analysis using pharmacy data from IADB.nl

    NARCIS (Netherlands)

    Visser, S.T.; Vegter, S.; Boersma, C.; De Grooth, R.; Postma, M.J.

    2010-01-01

    OBJECTIVES: Newer long-acting insulin analogs have shown to result in several treatment improvements if compared with NPH insulins. Promising results from clinical trials require confirmation from observational settings reflecting potential “real-life” benefits. Therefore, the current study aimed to

  10. Statement complementing the scientific opinion on application EFSA-GMO-NL-2010-78 to cover the safety of soybean MON 87705 oil for commercial frying

    OpenAIRE

    EFSA Panel on Genetically Modified Organisms (GMO)

    2013-01-01

    In this statement, the EFSA GMO Panel responds to a request from the European Commission (EC) to assess the safety of soybean MON 87705 oil for commercial frying. The applicant provided exposure assessments based on total and partial substitutions of conventional soybean, rapeseed and sunflower oils with the soybean MON 87705 oil in foods (salad dressings, margarines and spreads, mayonnaise, crackers and salty snacks and soybean/rapeseed/sunflower oils processed foods). No distinction was mad...

  11. Mammalian Toxicity of Munitions Compounds. Phase II. Effects of Multiple Doses Part II. 2,4-Dinitrotoluene

    Science.gov (United States)

    1978-11-01

    by Dr. Cheng-Chun Lee, Deputy Director, Biological Sciences Division, for Pharmacology and Toxicology with the asistance of Dr. Harry V. Ellis, I11...balance. Toxic signs seen in virtually all affected dogs included de- creased feed cunsumption, weight loss, yellow stain on and near hiud legs, ~i 1

  12. Thermal behaviour and antimicrobial assay of some new zinc(II) 2-aminobenzoate complex compounds with bioactive ligands

    Czech Academy of Sciences Publication Activity Database

    Krajníková, A.; Rotaru, A.; Györyová, K.; Homzová, K.; Manolea, H. O.; Kovářová, Jana; Hudecová, D.

    2015-01-01

    Roč. 120, č. 1 (2015), s. 73-83 ISSN 1388-6150 Institutional support: RVO:61389013 Keywords : antimicrobial * nicotinamide derivatives * non-isothermal kinetics Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.781, year: 2015

  13. Beten - und Kanonen kaufen. Evangelium und Gesetz im Zusammenhang von KD II/2 (§§ 36 - 39)

    DEFF Research Database (Denmark)

    Nielsen, Bent Flemming

    2010-01-01

    Med udgangspunkt i Karl Barths møde med danske teologer på Nyborg strand i 1939 analyseres en række bagvedliggende teologiske motiver for den samtale, som udspandt sig mellem Barth og de danske mødedeltagere. Det er en samtale, som er dokumenteret flere steder, og som blandt berører...

  14. Metallographic examinations of the wear-marks on fuel pins of the KNK II/2 fuel assembly NY-308

    International Nuclear Information System (INIS)

    Patzer, G.

    1987-12-01

    On the fuel pins and pin spacers of the fuel assembly NY-308 of the second core of KNK II pronounced wear marks had been found in the area of the contact points. In order to determine the exact form of the marks, metallographic investigations were performed on two test pieces of fuel pins in the Hot Cells of the KfK Karlsruhe. It was found that the wear marks did show the already observed stratified structure. Next to the unchanged cladding area there is a peripheral zone with modified grain structure, followed by a layer of moved material and finally there is a flake-like zone of accumulated cladding material at the lower end of the wear marks. Longitudinal cuts do not show grain deformations, which could indicate axial friction forces between pin and spacer. The wear marks are rapidly dropping to their maximum depth at the ends and the depth shows a relatively uniform pattern between both. The findings are confirming the picture, that a stirring movement of the fuel pins took place, which caused adhesive wear [de

  15. Edebî Tür Olarak Mektup, Hatıra ve Günlüklere Yansıyanlar: Çanakkale’de Savaşan Askerlerin Mektup Hatıra ve Günlüklerinde Yer Alan Motivasyon Unsurları

    Directory of Open Access Journals (Sweden)

    Korhan Altunyay

    2014-01-01

    Full Text Available Science of literature uses different genres such as diaries, memories and letters as both literary genres and a resource of research. These genres/resources are also used for psychological researches. Letters, memories and diaries are used to analyze the writer’s subconscious and to understand from which angle the writer looks at the problems, events and life. memories and diaries. In this paper, we will use letters, memories and diaries of our soldiers in the Battle of Canakkale in order to reveal the motivation behind their behavior.

  16. A knowledge federation architecture for rare disease patient registries and biobanks - See more at: http://www.lectitopublishing.nl/Article/Detail/9P2U85EL#sthash.YeeJGY0t.dpuf

    Directory of Open Access Journals (Sweden)

    Pedro Sernadela

    2016-03-01

    Full Text Available Patient registries are a source of standardized electronic patient information. These records are vital to identify and coordinate a proper cohort, especially for the rare disease domain. Likeness, biobanks are currently an essential instrument for biomedical research, since they provide the very first piece of the biomedical research cycle, i.e. the biological samples. However, connection between rare diseases, patient registries and biobanks has been very limited, due to the lack of common data models and procedures. As they were built with security and privacy in mind, available tools lack comprehensive data access mechanisms, thus making data sharing a complex process. To tackle these challenges, we introduce a semantic web-based architecture to connect distributed and heterogeneous registries and samples. The outcome is a unique knowledge layer, connecting miscellaneous datasets and enabling state-of-the-art semantic data sharing mechanisms.

  17. EFSA Panel on Genetically Modified Organisms (GMO); Scientific Opinion on an application (EFSAGMO-NL-2012-107) for the placing on the market of maize MON 810 pollen under Regulation (EC) No 1829/2003 from Monsanto

    DEFF Research Database (Denmark)

    Sørensen, Ilona Kryspin

    In this opinion, the EFSA GMO Panel addresses the safety of maize MON 810 pollen to complete the scope of an application (RX-MON 810) for the marketing of genetically modified maize MON 810 with the use of MON 810 pollen as or in food. Data on molecular characterisation of maize MON 810 did...... apply to the Cry1Ab protein expressed in MON 810 pollen. While the EFSA GMO Panel is not in a position to conclude on the safety of maize pollen in or as food in general, it concludes that the genetic modification in maize MON 810 does not constitute an additional health risk if maize MON 810 pollen...

  18. nlük akışlardaki boşlukların yapay sinir ağları kullanılarak tamamlanması

    OpenAIRE

    Yaşar, Mutlu

    2004-01-01

    Su kaynaklarının planlanmasına yönelik bir çok çalışmada, çevresel kirliliğin, iklimsel değişikliğin ve nüfusun hızla artışının etkisiyle optimum işletim sisteminin oluşturulması gün geçtikçe daha önemli olmaktadır. Planlama ve tasarım aşamasında, mevcut hidrolojik ve meteorolojik verilerin yeterliliği ve güvenilirliği değerlendirilmeli, yeterli veri yoksa, çeşitli kestirim yöntemleri ile bu veriler oluşturulmalıdır. Mevcut veriyle, hem su kaynaklan sistemlerinin davranışlarını tanımlamak hem...

  19. Elaboración de la matriz de geoindicadores ambientales en la presa José López Portillo (Cerro Prieto), fuente superficial de abastecimiento de agua potable de Monterrey, N.L., México

    OpenAIRE

    DE LEÓN GÓMEZ, HÉCTOR; MEDINA BARRERA, FRANCISCO; LIZÁRRAGA MENDIOLA, LILIANA

    2006-01-01

    Con el objetivo de conocer el estado del funcionamiento actual de la presa Cerro Prieto, en Linares, N. L., se elaboró la matriz de geoindicadores de impacto ambiental. Se basó en la aplicación de la metodología de matrices, considerando los tipos de impacto social/económico, geológico/ambiental y flora/fauna. Los resultados obtenidos son la base para la creación de un modelo de identificación de geoindicadores ambientales para presas de almacenamiento de agua potab...

  20. Forecasting Daily and Sessional Returns of the ISE-100 Index with Neural Network Models = Yapay Sinir Ağları Modelleri ile İMKB-100 Endeksinin Günlük ve Seanslık Getirilerinin Tahmin Edilmesi

    Directory of Open Access Journals (Sweden)

    Emin AVCI

    2007-06-01

    Full Text Available Especially for the last decade, the neural network models have been applied to solve financial problems like portfolio construction and stock market forecasting. Among the alternative neural network models, the multilayer perceptron models are expected to be effective and widely applied in financial forecasting. This study examines the forecasting power multilayer perceptron models for daily and sessional returns of ISE-100 index. The findings imply that the multilayer perceptron models presented promising performance in forecasting the ISE-100 index returns. However, further emphasis should be placed on different input variables and model architectures in order to improve the forecasting performances.

  1. Stimulation of innate immunity in newborn kids against Cryptosporidium parvum infection-challenge by intranasal/per-oral administration of liposomal formulation of N-L 18-norAbu-GMDP adjuvant

    Czech Academy of Sciences Publication Activity Database

    Turánek, J.; Kašná, A.; Koudela, Břetislav; Ledvina, Miroslav; Miller, A. D.

    2005-01-01

    Roč. 131, č. 5 (2005), s. 601-608 ISSN 0031-1820 R&D Projects: GA MZe QF3115 Institutional research plan: CEZ:AV0Z60220518; CEZ:AV0Z4055905 Keywords : Cryptosporidium parvum * immunomodulation * liposomes Subject RIV: EC - Immunology Impact factor: 1.703, year: 2005

  2. Økologisk risikovurdering af genmodificeret sojabønne-krydsning linje MON87769 x MON89788 (EFSA/GMO/NL/2010/85) i anmeldelse vedr. markeds¬føring under Forordning 1829/2003/EF

    DEFF Research Database (Denmark)

    Kjellsson, Gøsta; Damgaard, Christian; Sørensen, Jesper Givskov

    2011-01-01

    DMUs konklusioner vedr. den økologiske risikovurdering af den genmodificerede sojabønnekrydsning MON87769 x MON89788 i Danmark Den genmodificerede sojabønne MON87769 x MON89788 adskiller sig fra konventionelle sojabønner ved at have indsat gener der gør planten er blevet i stand til at producere...

  3. A single blind randomized controlled trial of cognitive behavioural therapy in a help-seeking population with an At Risk Mental State for psychosis: the Dutch Early Detection and Intervention Evaluation (EDIE-NL trial

    Directory of Open Access Journals (Sweden)

    Delespaul Philippe

    2010-03-01

    Full Text Available Abstract Background Psychotic disorders are a serious mental health problem. Intervention before the onset of psychosis might result in delaying the onset, reducing the impact or even preventing the first episode of psychosis. This study explores the effectiveness of cognitive behavioural therapy (CBT in targeting cognitive biases that are involved in the formation of delusions in persons with an ultra-high risk for developing psychosis. A single blind randomised controlled trial compares CBT with treatment as usual in preventing or delaying the onset of psychosis. Method/design All help seeking patients aged 14 to 35 years referred to the mental health services in three regions in the Netherlands are pre-screened with the Prodromal Questionnaire during a period of two years. Patients with a score of 18 or more on the sub-clinical positive symptoms items (45 items in total will be assessed with the Comprehensive Assessment of At Risk Mental State (CAARMS. In a different pathway to care model all referrals from the mental health services in Amsterdam to the specialized psychosis clinic of the Academic Medical Centre in Amsterdam are also assessed with the CAARMS. The primary outcome is the transition rate to psychosis according to the CAARMS-criteria. Group differences will be analysed with chi-square tests and survival analyses. Discussion CBT is a highly tolerated treatment. The psycho-educational CBT approach may prove to be a successful strategy since most people with an At Risk Mental State (ARMS are distressed by odd disturbing experiences. Giving explanations for and normalising these experiences may reduce the arousal (distress and therefore may prevent people from developing a catastrophic delusional explanation for their odd experiences and thus prevent them from developing psychosis. Screening the entire help-seeking population referred to community mental health services with a two-stage strategy, as compared with traditional referral to a specialist clinical psychosis centre, might detect more ultra-high-risk (UHR patients. This type of screening could be implemented in mental health care as routine screening. The trial is registered at Current Controlled trials as trial number ISRCTN21353122.

  4. Enhancing learners’ problem solving performance in mathematics: A cognitive load perspective - See more at: http://www.lectitopublishing.nl/Article/List/88/11/15#sthash.gmkglGIQ.dpuf

    Directory of Open Access Journals (Sweden)

    Joseph J. Dhlamini

    2016-03-01

    Full Text Available This paper reports on a pilot study that investigated the effect of implementing a context-based problem solving instruction (CBPSI to enhance the problem solving performance of high school mathematics learners. Primarily, the pilot study aimed: (1 to evaluate the efficiency of data collection instruments; and, (2 to test the efficacy of CBPSI in relation to learners’ problem solving performance. In this paper CBPSI refers to a teaching approach in which everyday problem solving knowledge and practices are uncovered when learners are exposed to tasks that give meaning to their everyday experiences. Given that the design of a pilot study lacked the inclusion of a control group, it is reasonable to conclude that the current design embraced elements of a pre-experimental research approach in which a one-group pre-test post-test design was followed. Participants consisted of a convenient sample of 57 Grade 10 learners who performed poorly in mathematics problem solving. The results of the study informed various conceptual and methodological revisions to strengthen the design of the main study, however, this paper reports only the effect of CBPSI on participants’ problem solving performance. The post-intervention achievement test suggested that CBPSI was effective in substantially accelerating learners’ problem solving performance (p<0.05. Using a cognitive load theory, it is possible to explain aspects of growth in learners’ problem solving performance in relation to the conceptual notion of human cognitive architecture.

  5. Dil ve Güvenlik: Avrupa Güvenlik ve İşbirliği Teşkilatı’nın Azınlık Dili Politikası

    OpenAIRE

    Erol, Ertan

    2017-01-01

    Soğuk Savaş döneminin sonları ile birlikte askerî güç odaklı güvenlik anlayışı daha fazla sorgulanmaya başlanmış ve özellikle güvenliğin politik, ekonomik, insani, toplumsal ve çevresel boyutları ön plana çıkmaya başlamıştır. Bu süreç içerisinde AGİT bünyesinde de güvenlik konusu, birbirinden soyutlanamayan; askeri-politik, ekonomik –çevresel ve insani olmak üzere üç boyutta ele alınmaktadır. Avrupa Güvenlik ve İşbirliği Teşkilatı (AGİT)’nın bu entegre güvenlik yapısı anlayı...

  6. Design Report for a 19-pin carbide test-bundle in a ring-subassembly of the test zone of KNK II/2

    International Nuclear Information System (INIS)

    Haefner, H.E.

    1982-03-01

    This report describes a 19-rod carbide test bundle in an annular oxide ring element placed at the position 201 of the test zone in the second core of KNK II as well as its behavior during the period of operation. The selected fuel rod concept includes low pellet density and a relatively large gap width as well as helium bonding between fuel and cladding. Characteristic design and operation data are: rod diameter 8.5 mm, pellet diameter 7.0 mm, maximum nominal linear rating 800 W/cm, maximum nominal burnup 70 MWd/kgHM. This report exclusively deals with the carbide test bundle and its individual components; it describes methods, criteria and results concerning the design. The annular carrier element with its head and foot is treated in a separate report. The loadability of the test bundle and its individual components is demonstrated by generally valid standards for strength criteria [de

  7. 4,4′-Bipyridine-aided synthesis and characterization of Zn(II) and Cd(II) 2-sulfoterephthalate complexes

    International Nuclear Information System (INIS)

    Xiao, Shan-Shan; Li, Xin-Xin; Zheng, Xiang-Jun; Jia, Tian-Jing; Jin, Lin-Pei

    2013-01-01

    Six d 10 complexes, [Zn 1.5 (stp)(bpy) 0.5 (H 2 O) 2 ]·0.5H 2 O (1), Cd 1.5 (stp)(bpy) 0.5 (H 2 O) 2 (2), [Cd 1.5 (stp)(bpy)(H 2 O)]·H 2 O (3), [Zn 0.5 (bpy) 0.5 (H 2 O) 2 ][Zn(stp)(bpy)(H 2 O)]·0.5H 2 O (4), Cd 3 (stp) 2 (bpy) 3 (H 2 O) 3 (5), Hbpy·[Zn 0.5 (bpy)(H 2 O) 2 ][Zn 0.5 (stp)(H 2 O)]·H 2 O (6) based on 2-sulfoterephthalate (stp 3− ) and 4,4′-bipyridine (bpy) have been synthesized under hydro/solvo-thermal conditions and structurally characterized. Complex 1 exhibits a three-fold interpenetrated 3D porous architecture. Complexes 2 and 3 possess helices with different chirality arranging alternately. 4 and 6 are addition compounds, which compose of complex cation and complex anion. Complex 5 features a 3D layer-pillar framework in which a (4, 4) grid layer is constructed by stp 3− ligands and Cd(II) ions, and the layers are further connected by bpy pillars. The solid-state luminescent properties of the coordination polymers have also been investigated. - Graphical abstract: Display Omitted - Highlights: • Complexes 1–3 possess helices with different chirality arranging alternately. • The structural diversity can be attributed to various coordination modes of ligands. • The formation of helical structure is related to the adjacent carboxyl and sulfonate groups. • Bpy exhibits three roles: bridge, hydrogen bonding acceptor, and template

  8. An orthogonal ferromagnetically coupled tetracopper(II) 2 x 2 homoleptic grid supported by micro-O4 bridges and its DFT study.

    Science.gov (United States)

    Roy, Somnath; Mandal, Tarak Nath; Barik, Anil Kumar; Pal, Sachindranath; Butcher, Ray J; El Fallah, Mohamed Salah; Tercero, Javier; Kar, Susanta Kumar

    2007-03-28

    A pyrazole based ditopic ligand (PzOAP), prepared by the reaction between 5-methylpyrazole-3-carbohydrazide and methyl ester of imino picolinic acid, reacts with Cu(NO3)2.6H2O to form a self-assembled, ferromagnetically coupled, alkoxide bridged tetranuclear homoleptic Cu(II) square grid-complex [Cu4(PzOAP)4(NO3)2] (NO3)2.4H2O (1) with a central Cu4[micro-O4] core, involving four ligand molecules. In the Cu4[micro-O4] core, out of four copper centers, two copper centers are penta-coordinated and the remaining two are hexa-coordinated. In each case of hexa-coordination, the sixth position is occupied by the nitrate ion. The complex 1 has been characterized structurally and magnetically. Although Cu-O-Cu bridge angles are too large (138-141 degrees) and Cu-Cu distances are short (4.043-4.131 A), suitable for propagation of expected antiferromagnetic exchange interactions within the grid, yet intramolecular ferromagnetic exchange (J = 5.38 cm(-1)) is present with S = 4/2 magnetic ground state. This ferromagnetic interaction is quite obvious from the bridging connections (d(x2-y2)) lying almost orthogonally between the metal centers. The exchange pathways parameters have been evaluated from density functional calculations.

  9. Design report for an annular fuel element for accommodation of a carbide test bundle on the ring position of the KNK II/2 test zone

    International Nuclear Information System (INIS)

    Haefner, H.E.

    1982-03-01

    This report describes an annular oxide element with Mark II rods for accommodation of a 19-pin carbide test bundle on position 201 in the test zone of the second core of KNK II as well as its behavior during the period of operation. The ring element comprises within a driver wrapper in three rows of pins 102 fuel pins of 7.6 mm diameter and six structural rods for fixing the spark eroded spacers. The report deals with the ring element with its individual components fuel rod, bundle, wrappers, head and foot and describes methods, criteria and results concerning the design. The carbide test bundle to be accommodated by the annular carrier element will be treated in a separate report. The loadability of the annular element with its components is demonstrated by generally valid standards for strength criteria

  10. Spectrophotometric analysis of vitamin E using Cu(I)-Bathocuproine or/and Fe(II)-2,4,6-tris-(2'-pyridyl)-s-triazine complexes

    International Nuclear Information System (INIS)

    Devi, I.; Memon, S. A.; Khuhawar, M.Y.

    2004-01-01

    Vitamin E (tocopherols and tocotrienols) antioxidants are determined by reducing Cu(II) to Cu(I) or Fe(III) to Fe(II) in presence of vitamin E and subsequent complexation of Cu(I) with bathocuproine and/or Fe(II) with 2,4,6-tris-(2'-pyridyl)-s-triazine (TPTZ). Both the reactions are monitored separately, Cu(I)-bathocuproine at 479 nm where as, Fe(II)-(TPTZ) at 595 nm spectrophotometrically. Linear calibration curves are achieved for both complexes between I to 5mu g ml-1 for vitamin E. The methods were applied for the determination of vitamin E in pharmaceutical preparations and edible oils. Vitamin E, from edible oils, was solvent extracted into n-hexane prior to saponification. Furthermore, a single lined flow was also examined. A larger excess of Cu(II) or Fe =(II) with different concentrations of vitamin E in buffer pH 4 was run on the line and constant amounts of reagent bathocuproine or TPTZ in each case was injected through the injector. The peak height shows a linear relationship for vitamin E between 0.5 to 2.5 mu g ml-1 for both complexes. (author)

  11. Crystal structure of triaqua(2,6-dimethylpyrazine-κN4bis(thiocyanato-κNmanganese(II 2,5-dimethylpyrazine disolvate

    Directory of Open Access Journals (Sweden)

    Stefan Suckert

    2015-12-01

    Full Text Available In the crystal structure of the title complex, [Mn(NCS2(C6H8N2(H2O3]·2C6H8N2, the MnII cation is coordinated by two terminally N-bonded thiocyanate anions, three water molecules and one 2,6-dimethylpyrazine ligand within a slightly distorted N3O3 octahedral geometry; the entire complex molecule is generated by the application of a twofold rotation axis. The asymmetric unit also contains an uncoordinating 2,5-dimethylpyrazine ligand in a general position. Obviously, the coordination to the 2,6-dimethylpyrazine ligand is preferred because coordination to the 2,5-dimethylpyrazine is hindered due to the bulky methyl group proximate to the N atom. The discrete complexes are linked by water-O—H...N(2,6-dimethylpyzazine/2,5-dimethylpyzazine hydrogen bonding, forming a three-dimensional network. In the crystal, molecules are arranged in a way that cavities are formed in which unspecified, disordered solvent molecules reside. These were modelled employing the SQUEEZE routine in PLATON [Spek (2015. Acta Cryst. C71, 9–18]. The composition of the unit cell does not take into account the presence of the unspecified solvent.

  12. (2,3,7,8,12,13,17,18-Octa-ethyl-porphyrinato-κ(4)N)cobalt(II)-2-nitro-benzaldehyde (1/2).

    Science.gov (United States)

    Mansour, Anissa; Daran, Jean-Claude; Nasri, Habib

    2012-09-01

    The asymmetric unit of the title compound, [Co(C(36)H(44)N(4))]·2C(7)H(5)NO(3), is composed of one half of the complex, arranged about an inversion center, and a complete 2-nitro-benzaldehyde (NBA) mol-ecule. The structure consists of columns that contain inter-leaved mol-ecules of NBA and [Co(II)(OEP)] (OEP is 2,3,7,8,12,13,17,18-octa-ethyl-porphyrin), which are stacked along the a axis. The Co(II) atom is involved in a π inter-action with the ring of the NBA mol-ecule with a centroid-metal distance of 3.508 (6) Å. There is an intra-molecular C-H⋯O hydrogen bond in the NBA mol-ecule.

  13. Ratiometric pH Imaging with a CoII2 MRI Probe via CEST Effects of Opposing pH Dependences (Postprint)

    Science.gov (United States)

    2017-10-13

    and a Varian 335 UV−vis detector. During HPLC experiments, H2O was used as solvent A and MeCN as solvent B. The absorbances at 220 and 285 nm were...Elemental analysis was conducted by Midwest Microlab Inc. Infrared spectra were recorded for solid samples of 1−3 on a Bruker Alpha FTIR spectrometer

  14. A Construction of the Real Time Monitoring System of the Solar Radio Disturbance: II. 2.8GHz Radio Receiver and Radio Environment

    Directory of Open Access Journals (Sweden)

    Yonggi Kim

    2008-03-01

    Full Text Available As the second step of the real time monitoring system of the solar radio disturbance, we constructed a 2.8 GHz radio receiver with 500 MHz bandwith. Using the control and observing system (Yoon et al.~2004, we observed the Sun, and found some frequencies, which disturb the Solar radio flux to be observed. DMB and aiport control frequencies are identified as responsible for this disturbance. As well as the testing the receiver, the measurment of the radio environment at 2.8 GHz with 500 MHz bandwith are carried out around Chungbuk National University. In fact, the radio power of the two frequencies, 2.649 GHz and 2.874 GHz is so high that we can not observe the Solar radio signal at 2.8 GHz. We report some results of this measurment and suggest the method to overcome this problem. We conclude also that the frequecies, which are important for the astronomy, should be protected in the future.

  15. Synthesis and Characterization of Novel Copper(II 2D Coordination Polymers from a Fluorinated Flexible Ligand with Remarkable Clathration Ability

    Directory of Open Access Journals (Sweden)

    Kayoko Kasai

    2011-11-01

    Full Text Available Two-dimensional (2D grid coordination polymers were prepared by the reaction of 1,4-bis(4-pyridylmethyltetrafluorobenzene (bpf with Cu(NO32 in the presence of aromatic compounds. Crystal structures of {[Cu(bpf2(NO32]·(biphenyl2}n (1, {[Cu(bpf2(NO32]·(m-C6H4(OMe22}n (2, {[Cu(bpf2(NO32]·PhtBu}n (3 and {[Cu(bpf2(NO3(H2O]NO3·(bpf0.5}n (4 were determined. The grid networks were held together by C–H···O and C–H···F hydrogen bonds via the NO3− anions and the tetrafluorophenylene rings of bpf, respectively. Biphenyl, m-dimethoxybenzene, t-butylbenzene, and bpf molecules were clathrated in cyclic cavities of the grid networks through arene-perfluoroarene interactions. These coordination networks have remarkable clathration ability for aromatic compounds.

  16. Adsorption in a Fixed-Bed Column and Stability of the Antibiotic Oxytetracycline Supported on Zn(II-[2-Methylimidazolate] Frameworks in Aqueous Media.

    Directory of Open Access Journals (Sweden)

    Janine dos Santos Ferreira da Silva

    Full Text Available A metal-organic framework, Zn-[2-methylimidazolate] frameworks (ZIF-8, was used as adsorbent material to remove different concentrations of oxytetracycline (OTC antibiotic in a fixed-bed column. The OTC was studied at concentrations of 10, 25 and 40 mg L(-1. At 40 mg L(-1, the breakthrough point was reached after approximately 10 minutes, while at 10 and 25 mg L(-1 this point was reached in about 30 minutes. The highest removal rate of 60% for the 10 mg L(-1 concentration was reached after 200 minutes. The highest adsorption capacity (28.3 mg g(-1 was attained for 25 mg L(-1 of OTC. After the adsorption process, a band shift was observed in the UV-Vis spectrum of the eluate. Additional studies were carried out to determine the cause of this band shift, involving a mass spectrometry (MS analysis of the supernatant liquid during the process. This investigation revealed that the main route of adsorption consisted of the coordination of OTC with the metallic zinc centers of ZIF-8. The materials were characterized by thermal analysis (TA, scanning electron microscopy (SEM, powder X-ray diffraction (XRD, and infrared spectroscopy (IR before and after adsorption, confirming the presence of OTC in the ZIF-8 and the latter's structural stability after the adsorption process.

  17. Soil/Rock Properties Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Soil/Rock Properties LaboratoryLocation: Spokane SiteThe Soil/Rock Properties Laboratory is contained in the soils bay, a 4,700 sq. ft. facility that provides space...

  18. 75 FR 34765 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2010-06-18

    ... personal identifying information from public review, we cannot guarantee that we will be able to do so. J... Arthur St, Spokane, 10000417 Whitman County Hutchison Studio, NE 200 Kamiaken St, Whitman, 10000418 [FR...

  19. Achievement report for fiscal 1998 on development of power generation using fuel cells. Research and development of molten carbonate fuel cell (II-2, text of the achievement); 1998 nendo nenryo denchi hatsuden gijutsu kaihatsu seika hokokusho. Yoyu tansan'engata nenryo denchi hatsuden system no kenkyu kaihatsu (II-2, kenkyu seika no honbun)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-05-01

    The effort aims at developing a 1000kW-class power plant and also at using gasified coal as fuel in the future. The fuel system facilities include a high-temperature blower. The exhaust heat recovery facilities comprise a heat recovery steam generator (HRSG) and a turbine compressor. As for the electrical system facilities, an inverter is installed, tested, and adjusted. Control system facilities are also tested and adjusted. In relation with the operation of the plant, coordination is conducted about technological and process-related matters with the Kawagoe thermal power station of Chubu Electric Power Co., Inc., where the fuel cell power plant is to be constructed, which is for the smooth execution of a test run. Ceramic-based cathode materials are being developed, which is for the fabrication of stacks improved in performance, higher in current density, longer in life, and lower in cost. Also exerted are efforts at developing multiple-function electrolyte plates and metallic materials (for example for separator plating). The extent of the acceptability of impurities concentration and gas refining systems are also under study, which is to prepare for future coal gasification. Reference is also made to the study of a total system. (NEDO)

  20. Habitat Evaluation Procedures (HEP) Report : Grand Coulee Dam Mitigation, 1996-1999 Technical Report.

    Energy Technology Data Exchange (ETDEWEB)

    Kieffer, B.; Singer, Kelly; Abrahamson, Twa-le

    1999-07-01

    The purpose of this Habitat Evaluation Procedures (HEP) study was to determine baseline habitat units and to estimate future habitat units for Bonneville Power Administration (BPA) mitigation projects on the Spokane Indian Reservation. The mitigation between BPA and the Spokane Tribe of Indians (STOI) is for wildlife habitat losses on account of the construction of Grand Coulee Dam. Analysis of the HEP survey data will assist in mitigation crediting and appropriate management of the mitigation lands.

  1. Planning for success

    International Nuclear Information System (INIS)

    Lagassa, G.; Anderson, J.L.

    1992-01-01

    This article examines successful hydroelectric projects to determine how they dealt with licensing, relicensing, and environmental mitigation issues. The topics addressed in the article include addressing project feasibility doubts and fisheries protection at the New York State Dam Hydroelectric facility on the Mohawk River, and fisheries protection, construction space limits and cofferdam construction on the Spokane River during the Monroe Street Powerhouse Hydroelectric Redevelopment project in downtown Spokane, Washington

  2. Dicty_cDB: SSL761 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available LKKCPKGFSFFGSIG CDDFIKNYSKKYPDVEIGGRHTDSFTLF--- ---NHHSHFTHLLLLCYECFENTGY*i*wifiqhsdlyivkw*nl**gyshstyfevsei...vekvskrififwfnwm **fh*klfkeisrc*nwwssyrlfyiiw--- ---NHHSHFTHLLLLCYECFENTGY*i*wifiqhsdlyivkw*nl**gyshstyfevse

  3. Self-assembly of linear [Mn II 2 Mn III ] units with end-on azido bridges: the construction of a ferromagnetic chain using S T = 7 high-spin trimers

    KAUST Repository

    Jiang, Yuan

    2015-01-01

    © The Royal Society of Chemistry 2015. The controlled organization of high-spin complexes into 1D coordination polymers is a challenge in molecular magnetism. In this work, we report a ferromagnetic Mn trimer Mn3(HL)2(CH3OH)6(Br)4·Br·(CH3OH)21 (H2L = 2-[(9H-fluoren-9-yl)amino]propane-1,3-diol) with the ground spin state of ST = 7 that can be assembled into a one-dimensional coordination chain [Mn3(HL)2(CH3OH)2(Br)4(N3)(H2O)·CH3OH]∞2 using azido bridging ligands. Interestingly, the ferromagnetic nature of 1 is well retained in 2. However, due to the negligible magnetic anisotropy in 1, both 1 and 2 do not show slow-relaxation of magnetization, which indicates that during the process of molecular assembly not only the intratrimer magnetic interaction but also the magnetic anisotropy of the trimer can be reserved.

  4. A novel photo-active Cd:1,4-benzene dicarboxylate metal organic framework templated using [Ru(ii)(2,2'-bipyridine)3]2+: synthesis and photophysics of RWLC-5.

    Science.gov (United States)

    Larsen, Randy W; Mayers, Jacob M; Wojtas, Lukasz

    2017-09-26

    The development of photoactive porous materials is of significant importance for applications ranging from sustainable energy to pharmaceutical development and catalysis. A particularly attractive class of photo-active materials is the metal-organic framework (MOF)-based platform in which the photo-active elements are components of the framework itself or photo-active guests encapsulated within the MOF cavities. It has now been demonstrated that the photo-active [Ru(2,2'-bipyridine) 3 ] 2+ (RuBpy) complex can template the formation of MOFs with varying three dimensional structures. Here we report the synthesis and structural and photo-physical characterization of a new RuBpy-templated MOF composed of Cd 2+ ions with 1,4-benzenedicarboxylate ligands (RWLC-5) that contains crystallographically resolved RuBpy complexes. The new material displays a biphasic emission decay (130 ns and 1180 ns, T = 20 °C) and a bathochromically shifted emission maximum, relative to RuBpy in solution (603 nm for RuBpy in ethanol vs. 630 nm for RWLC-5). The emission lifetimes also do not display temperature-dependent decays which are characteristic of RuBpy type complexes as well as other RuBpy templated MOFs. The lack of temperature dependence is consistent with the complete deactivation of the 3 LF state of the encapsulated RuBpy complex due to a constrained environment. The fast phase decay is attributed to a water molecule hydrogen bonded to a bipyridine ligand associated with ∼38% of the encapsulated RuBpy complexes resulting in the nonradiative deactivation of the 3 MLCT state.

  5. Sonochemical synthesis of two novel Pb(II) 2D metal coordination polymer complexes: New precursor for facile fabrication of lead(II) oxide/bromide micro-nanostructures.

    Science.gov (United States)

    Hayati, Payam; Suárez-García, Salvio; Gutierrez, Angel; Şahin, Ertan; Molina, Daniel Ruiz; Morsali, Ali; Rezvani, Ali Reza

    2018-04-01

    Two new lead(II) coordination polymer complexes (CSCs) (2D), [Pb 2 (L) 2 (Br) 2 ] n ·H 2 O (1), [Pb 2 (HL / )(L / )(H 2 O) 2 ] n ·H 2 O (2), where L = C 6 H 5 NO 2 (2-pyridinecarboxylic acid) and L /  = C 9 H 6 O 6 (1,3,5-tricarboxylic acid), have been synthesized under different experimental conditions. Micrometric crystals (bulk) or microsized materials have been obtained depending on using the branch tube method or sonochemical irradiation. All materials have been characterized by scanning electron microscopy (SEM), powder X-ray diffraction (PXRD) and FT-IR spectroscopy. Single crystal X-ray analyses on complexes 1 and 2 shows that Pb 2+ ions are 8-coordinated, 7 and 9-coordinated, respectively. Topological analysis shows that the compound 1 and 2 are 4,6L26 and bnn net, respectively. However, neither the shape nor the morphology is maintained, showing the role of sonochemistry to modulate both morphology and dimensions of the resulting crystalline material, independently of whether we have a 2D coordination polymer (CP). Finally, micro structuration of lead(II) bromide oxide and lead(II) oxide have been prepared by calcination of two different lead (II) CPs at 700 °C that were characterized by SEM and XRD. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. On-line dilution flow injection manifold for the selective spectrophotometric determination of ascorbic acid based on the Fe(II)-2,2'-dipyridyl-2-pyridylhydrazone complex formation.

    Science.gov (United States)

    Themelis, D G; Tzanavaras, P D; Kika, F S

    2001-08-03

    A new simple and rapid FI method for the accurate and precise spectrophotometric determination of ascorbic acid (AsA) in pharmaceutical formulations is reported. The method is based on the reduction of Fe(III) to Fe(II) by the analyte, and the subsequent reaction of the produced Fe(II) with 2,2'-dipyridyl-2-pyridylhydrazone (DPPH) in acidic medium (pH ca. 2.5) to form a colored complex (lambda(max)=535 nm). An on-line dilution mode using a binary inlet static mixer (BISM) was incorporated in the FI system, allowing the determination of the analyte in a wide concentration range. The calibration graph was linear in the range of 5.7-600.0 mg l(-1) AsA, at a sampling rate of 120 injections h(-1). The method was found to be very precise [s(r)=0.1% at 300 mg l(-1) AsA (n=12)] and the 3delta detection limit (c(L)=1.7 mg l(-1)) was quite satisfactory. The detailed study of various interferences confirmed the high selectivity of the proposed method. Its application to a variety of pharmaceuticals produced excellent results, with a mean relative error of e(r)<1.0%.

  7. Crystal structure of triaqua(1,10-phenanthroline-κ2N,N′(2,4,5-trifluoro-3-methoxybenzoato-κO1cobalt(II 2,4,5-trifluoro-3-methoxybenzoate

    Directory of Open Access Journals (Sweden)

    Junshan Sun

    2014-11-01

    Full Text Available The title salt, [Co(C8H4F3O3(C12H8N2(H2O3](C8H4F3O3, was obtained under solvothermal conditions by the reaction of 2,4,5-trifluoro-3-methoxybenzoic acid with CoCl2 in the presence of 1,10-phenanthroline (phen. The CoII ion is octahedrally coordinated by two N atoms [Co—N = 2.165 (2 and 2.129 (2 Å] from the phen ligand, by one carboxylate O atom [Co—O = 2.107 (1 Å] and by three O atoms from water molecules [Co—O = 2.093 (1, 2.102 (1 and 2.114 (1 Å]. The equatorial positions of the slightly distorted octahedron are occupied by the N atoms, the carboxylate O and one water O atom. An intra- and intermolecular O—H...O hydrogen-bonding network between the water-containing complex cation and the organic anion leads to the formation of ribbons parallel to [010].

  8. Self-assembly of linear [Mn(II)2Mn(III)] units with end-on azido bridges: the construction of a ferromagnetic chain using ST = 7 high-spin trimers.

    Science.gov (United States)

    Jiang, Yuan; Qin, Lei; Li, Guanghua; Abbas, Ghulam; Cao, Yaqun; Wu, Gang; Han, Tian; Zheng, Yan-Zhen; Qiu, Shilun

    2015-03-21

    The controlled organization of high-spin complexes into 1D coordination polymers is a challenge in molecular magnetism. In this work, we report a ferromagnetic Mn trimer Mn3(HL)2(CH3OH)6(Br)4·Br·(CH3OH)2 1 (H2L = 2-[(9H-fluoren-9-yl)amino]propane-1,3-diol) with the ground spin state of ST = 7 that can be assembled into a one-dimensional coordination chain [Mn3(HL)2(CH3OH)2(Br)4(N3)(H2O)·CH3OH]∞ 2 using azido bridging ligands. Interestingly, the ferromagnetic nature of 1 is well retained in 2. However, due to the negligible magnetic anisotropy in 1, both 1 and 2 do not show slow-relaxation of magnetization, which indicates that during the process of molecular assembly not only the intratrimer magnetic interaction but also the magnetic anisotropy of the trimer can be reserved.

  9. TiO2/Chitosan-NH4I(+I2-BMII-Based Dye-Sensitized Solar Cells with Anthocyanin Dyes Extracted from Black Rice and Red Cabbage

    Directory of Open Access Journals (Sweden)

    M. H. Buraidah

    2011-01-01

    Full Text Available Dye sensitized solar cells (DSSCs were fabricated using anthocyanin dye and polymer electrolyte with ammonium iodide (NH4I salt. The study was designed to focus on increasing the efficiency of the DSSC. DSSC using 26.9 wt. % chitosan-22 wt. % NH4I(+2.2 wt.% I2-48.9 wt. % IL solid electrolyte, black rice anthocyanin with Pt counter electrode showed Jsc of 172 μA cm−2 and Voc of 195 mV. The performance of the cell with Pt electrode was further improved by coating a blocking layer on the indium tin oxide (ITO substrate. The black rice DSSC using 11 wt. % (chitosan:PEO, wt. ratio 30:70-9 wt. % NH4I-80 wt. % BMII gel electrolyte exhibited Jsc of 1213 μA cm−2, Voc of 400 mV, FF of 0.47, and η of 0.23%. The red cabbage anthocyanin DSSC containing (phthaloyl chitosan-PEO-NH4I-BMII gel electrolyte using tartaric acid to adjust the pH of anthocyanin solution showed the best performance with the fill factor of 0.39, Jsc of 3503 μA cm−2, Voc of 340 mV, and an overall conversion efficiency of 0.46%.

  10. An irresolute linker: separation, and structural and spectroscopic characterization of the two linkage isomers of a Ru(ii)-(2-(2'-pyridyl)pyrimidine-4-carboxylic acid) complex.

    Science.gov (United States)

    Iengo, E; Demitri, N; Balducci, G; Alessio, E

    2014-08-28

    For the first time the two linkage isomers of a Ru(ii) complex with 2-(2'-pyridyl)pyrimidine-4-carboxylic acid (cppH) - that form in comparable amounts - have been fully characterized individually. The X-ray structure of each isomer is related to its NMR spectrum in solution.

  11. Koroner arter hastalığında aspirin direnci ile koroner arter hastalığı yaygınlığı ve tekrarlayan perkütan koroner girişimler arasındaki ilişki

    OpenAIRE

    Kahraman, Serkan

    2013-01-01

    Giriş: Vasküler yataklardaki akut iskemik sendromların primer nedeni olan aterotromboz tüm dünyadaki ölümlerin %35’inden fazlasını oluşturmakta olup trombotik komplikasyonlarla ilişkili aterotrombotik lezyon rüptürü ile karakterizedir. Aspirin aterotrombotik hastalıklardan ve komplikasyonlarından primer ve sekonder korunmada kullanılan etkili bir antitrombositer ilaçtır. Aspirin trombositlerdeki siklooksijenaz-1 (COX-1) enzimini serin rezidülerini asetilleyerek geridönüşümsüz olarak inhibe ed...

  12. Perkembangan Seni Beladiri Wushu Di Kota Medan Tahun (2001-2013) 印尼棉兰人武术传统的发展研究(Yìnní miánlán rén wǔshù chuántǒng de fāzhǎn yánjiū)

    OpenAIRE

    Purba, Dedi A.

    2015-01-01

    The title of this research is “ Perkembangan Seni Beladiri Wushu di Kota Medan ( 2001 – 2013)”. In this research, the writer is trying to describe the Wushu, especially in the development of wushu martial arts . Due the title, there are some concepts written in chapter two, they are development, martial arts and wushu. The theory used in this research is social theory or culture theory, that is used to analysis the development of wushu martial arts . The methodology used on the research to ...

  13. Report on feasibility study for introduction of biomass energy in Town of Kuzumaki. Town of milk, wine and clean energy, located at N.L. 40 degrees; Kuzumakicho biomass energy donyu kanosei chosa hokokusho. Hokui 40 do, milk to wine to clean energy no machi

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-02-01

    The feasibility study is conducted specifically for construction of a biomass plant in drawing the new energy visions for Town of Kuzumaki, Iwate Pref. The town is raising domestic animals, approximately 10,700 dairy cattle, 900 beef cattle, 2,800 hogs, and 18,000 chickens, actively producing the products, including approximately 40,000 tons/y of milk. On the other hand, these animals are discharging the excreta totaling around 500 tons/d, and adequate disposal and most effective utilization of the excreta as the resources provide the challenges to overcome. The project for constructing a demonstration model investigates treatment of the excreta discharged from 200 dairy cattle by an anaerobic fermentation plant, which uses the excreta and other organic wastes as the stock materials, and utilization of the biogas energy produced by the plant. The project is also considering to demonstrate the cycles of utilization of the digested sludge discharged from the fermentation process as the organic liquid compost. The economic evaluation results indicate that the plant gains a total income of 8.715 million/yen at a total expense of 8.575 million yen/y. (NEDO)

  14. EFSA Panel on Genetically Modified Organisms (GMO); Scientific Opinion on application (EFSAGMO- NL-2007-39) for the placing on the market of insect resistant and herbicide tolerant genetically modified maize MON89034 x MON88017 for food and feed uses, import and processing under Regulation (EC

    DEFF Research Database (Denmark)

    Sørensen, Ilona Kryspin

    This opinion reports on an evaluation of a risk assessment for placing on the market the genetically modified herbicide tolerant and insect resistant maize MON89034 x MON88017 for food and feed uses, import and processing. Conventional breeding methods were used in the production of maize MON89034...... demonstrated to be comparable with those of the single events. The comparative analysis of compositional, phenotypic and agronomic characteristics of this GM maize indicated equivalence with its conventional counterpart and commercial non-GM maize varieties except for the expression of the target proteins...

  15. Türkiye’nin Mukayeseli Üstünlüğe Sahip Olduğu Hizmet Alt Sektörlerinden İnşaat; Sorunlar ve İmkanlar(Construction, As One Of The Sub-Service Sectors In Which Turkey Has Comparative Advantages; Issues and Possibilities

    Directory of Open Access Journals (Sweden)

    Mehmet Behzat EKİNCİ

    2006-01-01

    Full Text Available Each country has some advantages in production. A country endeavours to increase production of goods and services through its comparative advantages, and thus raises its income level by trading them. It is “Theory of Comparative Advantages” that is mainly used in International Economics for explaining the matter. Various factors among advantages that a country has in trade in services may be mentioned. For instance; the factors such as human capital, information accumulation, technological infrustructure and skills endowment are some of them. Therefore, a country can realize its production relatively cheaper by benefiting from such advantages, and it might increase its commercial share worldwide. All countries can not be successful in all sub-service sectors at the same level. Consequently, according to the Theory of Comparative Advantages, as it is in trade in goods, they should specialize only on some sub-service sectors. Thus, it will be possible to be more successful in international trade. Turkey also has some comparative advantages in trade in services. So, it is possible to determine which sub-service sectors it has comparative advantages in. When doing this, some classifications might be used. According to one of the classifications that can be used in this context, services are taken into account in two categories which are “Information based” and “Traditional”. In this article, “construction sector” as one of the “information based services” is dealt with. In context of construction sector, “architecture-engineering services, technical consultancy services and contracting services” are studied. In the article, first of all, the share of Turkey in trade in services is researched. Then, construction sector as to its sub-services is studied in details.

  16. NUEVE JUECES ENTRAN EN DIÁLOGO CON NUEVE HIPÓTESIS ACERCA DE LA PRUEBA DE LOS HECHOS EN EL CONTEXTO PENAL NlNE JUDGES ENTER INTO DIALOGUE WITH NINE HYPOTHESES ABOUT THE PROOF OF FACTS IN CRIMINAL CASES

    Directory of Open Access Journals (Sweden)

    Rodrigo Coloma C

    2010-01-01

    Full Text Available En el presente artículo se formulan nueve hipótesis que refieren a la prueba de los hechos en el proceso penal, las cuales son analizadas por nueve jueces de Tribunal de Juicio Oral y de Garantía. Siete de ellas pretenden describir distintas prácticas que se darían en los tribunales de justicia y las dos restantes refieren a cómo debieran actuar los jueces en ciertos casos difíciles. Las temáticas abordadas son agrupadas en las siguientes categorías: a alcances del compromiso que tendrían los jueces de operar con historias verdaderas como soportes de sus decisiones; b dificultades que surgen como consecuencia de la debilidad epistémica de la prueba disponible en los juicios y de los posibles sesgos en su interpretación; c exigencias asociadas a la valoración de la prueba conforme a la sana crítica, y d significado que debiera ser atribuido al estándar de prueba del más allá de toda duda razonable. De esta manera, se lleva a cabo un diálogo entre el sistema de creencias propio de los jueces y del que resulta frecuente entre los juristas.This article formulates nine hypotheses concerning the proof of facts in criminal proceedings, which are analysed by nine judges of Chilean criminal Courts (Tribunal de Juicio Oral y de Garantía. Seven hypotheses aimed at describing different practices that take place in the courts and two of them concern how judges should act in certain hard cases. The matters are grouped in the following categories: a scopes of the compromise that judges should have in order to opérate with true stories as support oftheir decisions; b difficulties that arise as consequence of the epistemic weakness of the evidence available in triáis and the possible slants in their interpretation; c requirements of the evaluation of the proof according to the sana crítica; and d meaning that should have the standard of proof beyond reasonable doubt. In this way a dialogue between the system ofbeliefs of judges and of jurists takes place.

  17. Turkish conformation of the physical education predisposition scale: A validity and reliability study [Beden eğitimi dersi yatkınlık ölçeğinin Türkçe uyarlaması: geçerlik ve güvenirlik çalışması

    Directory of Open Access Journals (Sweden)

    Mustafa Kayıhan ERBAŞ

    2015-04-01

    Full Text Available The Physical Education Predisposition Scale (PEPS developed by Hilland et al. (2009 was designed to measure levels of predisposition to physical education courses. In this study, a Turkish adaptation of the scale is examined in regard to span in which they would and is intended to determine the trust. Research was conducted in the school districts of the province of Aksaray, Turkey, and included 7 secondary schools. The study included 57 females (43% and 75 males (57% for a total of 132 students (Mage = 12.968, SD = 0.819. A two-factor scale was used for factor analysis and the analysis of the basic components in the scale, and the total variance was found to be 63.29. Cronbach’s coefficient Alpha reliability was 0.71. Accordingly, based on the physical education of secondary school students in Turkey, the scale for determining the disposition can be said to be a valid and reliable scale.

  18. William Wordsworth's 'Double Awareness' of Memory in Virginia Woolf's Mrs Dalloway = William Wordsworth'un 'Hatıranın Çift Yönlü Algılaması' Kavramının Virgina Woolf'un Mrs Dalloway Adlı Romanındaki Kullanımı

    Directory of Open Access Journals (Sweden)

    Ali GÜNEŞ

    2003-06-01

    Full Text Available This article deals with Romanticism in modernist British writer Virginia Woolf's novel, Mrs Dalloway. Although her works are experimental and new, they are part of a wider and developing perspective in the historical process of literary tradition, so that they cannot be viewed as completely breaking away from literary tradition, but rather as a reworking and redevelopment in its evolution. In her reworking of the traditional novel, this paper may suggest that Woolf made it "new" by returning to the Romantics, particularly to Wordsworth. By this claim, this paper does not mean that Woolf copied Wordsworth exactly, but was profoundly and pervasively influenced by his aesthetic views, especially in relation to her understanding of life as "consciousness". By returning to the Romantics, Woolf develops her sense of "reality" as both fragmented and whole, and of the "self" as fragmented but desiring and imagining unity. Hence she not only strove to construct a poetical or lyrical novel to express that contradictory view but also used her fiction to explore the mystery of the subjective consciousness as the dominant modernist view. In order to express her perception of modernist identity, Woolf used memory as a device in Mrs Dalloway and thus developed a new way of narration as well as a new view of human identity. By means of this new method, she left the objective narration of the traditional novel, and thus meaning or the view of identity in Woolf's late fiction is not static but undecided, unfinished and mysterious.

  19. Scientific Opinion on application EFSA-GMO-NL-2011-93 for the placing on the market of the herbicide-tolerant genetically modified soybean MON 87708 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 from Monsanto

    OpenAIRE

    Arpaia, Salvatore; Birch, Andrew N E; Chesson, Andrew; du Jardin, Patrick; Gathmann, Achim; Gropp, Jürgen; Herman, Lieve; Hoen-Sorteberg, Hilde-Gunn; Jones, Huw; Kiss, Jozsef; Kleter, Gijs; Lovik, Martinus; Messéan, Antoine; Naegeli, H; Nielsen, Kaare Magne

    2013-01-01

    Soybean MON 87708 contains a single insert consisting of the dmo expression cassette. The DMO (dicamba mono-oxygenase) proteins confer tolerance to dicamba-based herbicides. Bioinformatic analyses of the inserted DNA and flanking regions do not raise safety issues. The levels of DMO proteins in soybean MON 87708 have been sufficiently analysed. The stability of the genetic modification has been demonstrated. No differences were identified in the compositional data of forage and seeds obtained...

  20. Sustainable land use from a farmers' perspective; report on the contribution by the Sociological Team (NL2) to an international research project 'Regional guidelines to support sustainable land use (regulation 2078/92)' focussing on Waterland, a peat meadow district North of Amsterdam, as an exemplary case for 'Wider farm development'

    NARCIS (Netherlands)

    Ploeg, van der B.

    1999-01-01

    This is a report about a Peat Meadow District called Waterland, as an exemplary case of Wider Farm Development. The case study is about farmers who develop New Countryside Activities, and how this is influenced by their basic occupational attitudes and by emerging local institutions for exchange

  1. Karanlık ve Aydınlıkta Depolanmış Ayvalık ve Memecik Çeşidi Natürel Zeytinyağlarının Spektroskopik Verilere Göre Kemometrik Sınıflandırılması

    Directory of Open Access Journals (Sweden)

    Betül Öztürk

    2015-02-01

    Full Text Available Bu çalışmada, Türkiye’nin zeytinyağı üretiminin % 65’ini Oluşturan Ege bölgesinin hakim zeytin çeşidi olan Ayvalık ve Memecik yağ örneklerinin en yaygın spektroskopik yöntemler ile (FTNIR, FTIR-ATR, Excitation-Emission [EX-EM] ve Senkronize [SYN] Floresans Spektroskopisi analiz edilerek sınıflandırılması gerçekleştirilmiştir. Analiz edilen yağ örnekleri organik ve karışık çeşitlerden üretilen bir örnek dışında Kuzey Ege (Ayvalık çeşidi (n=4 ve Güney Ege (Memecik çeşidi (n=4 alt bölgelerinden alınmış toplam 9 adetten Oluşmaktadır. Oda sıcaklığında PET şişeler içinde muhafaza edilen yağ örnekleri gün ışığına maruz bırakılan ve aluminyum folyo ile kaplanmış (karanlık olarak iki gruba ayrılmıştır. Ayvalık ve Memecik çeşidi natürel zeytinyağlarının sınıflandırılması en yaygın kullanılan kemometrik yöntemler ile (Temel Bileşen Analizi, PCA ve Aşamalı Kümeleme Analizi, HCA gerçekleştirilmiştir. Ayvalık ve Memecik çeşitleri spektroskopik yöntemlerin sonuçları temelinde çeşit, orijin bölgesi ve işlem uygulamalarına (ışığa maruz kalma veya karanlıkta tutma gibi göre dikkate değer bir şekilde sınıflanmışlardır. Ayrıca, spektroskopik yöntemlerin natürel zeytinyağların sınıflandırılmasında ve muhtemel depolama koşulları ve tağşiş konusunda ümitvar etkiler sergileyebileceği görülmüştür.

  2. Wildlife Mitigation and Restoration for Grand Coulee Dam: Blue Creek Project, Phase 1.

    Energy Technology Data Exchange (ETDEWEB)

    Merker, Christopher

    1993-04-01

    This report is a recommendation from the Spokane Tribe to the Northwest Power Planning Council (NPPC) for partial mitigation for the extensive wildlife and wildlife habitat losses on the Spokane Indian Reservation caused by the construction of Grand Coulee Dam. NPPC`s interim wildlife goal over the next 7 years for the Columbia hydropower system, is to protect, mitigate and enhance approximately 35% basin wide of the lost habitat units. Grand Coulee Dam had the greatest habitat losses of any Dams of the Wildlife Rule.

  3. Crystal Structure of the Extracellular Cholinesterase-Like Domain from Neuroligin-2

    Energy Technology Data Exchange (ETDEWEB)

    Koehnke,J.; Jin, X.; Budreck, E.; Posy, S.; Scheiffele, P.; Hnoig, B.; Shapiro, L.

    2008-01-01

    Neuroligins (NLs) are catalytically inactive members of a family of cholinesterase-like transmembrane proteins that mediate cell adhesion at neuronal synapses. Postsynaptic neuroligins engage in Ca2+-dependent transsynaptic interactions via their extracellular cholinesterase domain with presynaptic neurexins (NRXs). These interactions may be regulated by two short splice insertions (termed A and B) in the NL cholinesterase domain. Here, we present the 3.3- Angstroms crystal structure of the ectodomain from NL2 containing splice insertion A (NL2A). The overall structure of NL2A resembles that of cholinesterases, but several structural features are unique to the NL proteins. First, structural elements surrounding the esterase active-site region differ significantly between active esterases and NL2A. On the opposite surface of the NL2A molecule, the positions of the A and B splice insertions identify a candidate NRX interaction site of the NL protein. Finally, sequence comparisons of NL isoforms allow for mapping the location of residues of previously identified mutations in NL3 and NL4 found in patients with autism spectrum disorders. Overall, the NL2 structure promises to provide a valuable model for dissecting NL isoform- and synapse-specific functions.

  4. 77 FR 39322 - Notice to Rescind the Notice of Intent to Prepare an Environmental Impact Statement (EIS...

    Science.gov (United States)

    2012-07-02

    ... at the Seltice Way Interchange, a new interchange or an I-90 grade separation at Greensferry Road, an... lanes and/or collector distributor roads on I-90 from the Spokane Street Interchange to the SH 41... interchange to the west at approximately milepost (MP 4.3) and State Highway (SH) 41 interchange...

  5. Mileposts of progress in fire control and fire research

    Science.gov (United States)

    H. T. Gisborne

    1942-01-01

    At Spokane, a month ago, Dr. Carl F. Taeusch of the Bureau of Agricultural Economics told us that for common understanding of any problem it is essential that we first establish the "framework of ideas within which we are trying to work out the problem." Walter B. Pitkin stresses the same point when he says: "The next task is to take some position toward...

  6. 76 FR 81987 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-12-29

    ..., Personal Insurance Division, Tele- Workers to this Location. 81,085 Western United Life Spokane, WA........ February 13, 2010. Assurance Company, Global Life Holdings, LLC, Insurance Administration, etc. 81,091... trade adjustment assistance for workers by (TA-W) number issued during the period of December 12, 2011...

  7. Concentrations and loads of cadmium, zinc, and lead in the main stem Coeur d'Alene River, Idaho—March, June, September, and October 1999

    Science.gov (United States)

    Woods, P.F.

    2001-01-01

    The Remedial Investigation/Feasibility Study conducted by the U.S. Environmental Protection Agency within the Spokane River Basin of northern Idaho and eastern Washington included extensive data-collection activities in numerous studies to determine the nature and extent of trace-element contamination within the basin. The objective of this particular study was to improve our understanding

  8. Ham on Regal.

    Science.gov (United States)

    Hubbard, Russ

    1985-01-01

    Teachers at Ferris High School in Spokane, Washington, are joined by the parents of high school students in the production of elaborate annual shows that both create a sense of community and raise approximately $10,000 a year for the school. (PGD)

  9. Blue Creek Winter Range : Wildlife Mitigation Project : Final Environmental Assessment.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration; United States. Bureau of Indian Affairs; Spokane Tribe of the Spokane Reservation, Washington

    1994-11-01

    Bonneville Power Administration (BPA) proposes to fund that portion of the Washington Wildlife Agreement pertaining to the Blue Creek Winter Range Wildlife Mitigation Project (Project) in a cooperative effort with the Spokane Tribe, Upper Columbia United Tribes, and the Bureau of Indian Affairs (BIA). If fully implemented, the proposed action would allow the sponsors to protect and enhance 2,631 habitat units of big game winter range and riparian shrub habitat on 2,185 hectares (5,400 acres) of Spokane Tribal trust lands, and to conduct long term wildlife management activities within the Spokane Indian Reservation project area. This Final Environmental Assessment (EA) examines the potential environmental effects of securing land and conducting wildlife habitat enhancement and long term management activities within the boundaries of the Spokane Indian Reservation. Four proposed activities (habitat protection, habitat enhancement, operation and maintenance, and monitoring and evaluation) are analyzed. The proposed action is intended to meet the need for mitigation of wildlife and wildlife habitat adversely affected by the construction of Grand Coulee Dam and its reservoir.

  10. Blue Creek Winter Range: Wildlife Mitigation Project. Final environmental assessment

    International Nuclear Information System (INIS)

    1994-11-01

    Bonneville Power Administration (BPA) proposes to fund that portion of the Washington Wildlife Agreement pertaining to the Blue Creek Winter Range Wildlife Mitigation Project (Project) in a cooperative effort with the Spokane Tribe, Upper Columbia United Tribes, and the Bureau of Indian Affairs (BIA). If fully implemented, the proposed action would allow the sponsors to protect and enhance 2,631 habitat units of big game winter range and riparian shrub habitat on 2,185 hectares (5,400 acres) of Spokane Tribal trust lands, and to conduct long term wildlife management activities within the Spokane Indian Reservation project area. This Final Environmental Assessment (EA) examines the potential environmental effects of securing land and conducting wildlife habitat enhancement and long term management activities within the boundaries of the Spokane Indian Reservation. Four proposed activities (habitat protection, habitat enhancement, operation and maintenance, and monitoring and evaluation) are analyzed. The proposed action is intended to meet the need for mitigation of wildlife and wildlife habitat adversely affected by the construction of Grand Coulee Dam and its reservoir

  11. 78 FR 50443 - Notice of Temporary Closure to Target Shooting on Public Lands in Yakima County, WA

    Science.gov (United States)

    2013-08-19

    ..., Spokane District, Bureau of Land Management (BLM). After review and coordination with special interest... shooting and target shooting practice has increased significantly over the past few years and is important... noise from gunfire has negatively affected their quality of life. There is also a concern that given the...

  12. Diplomas and Diapers: Schooling for Young Street Mothers and Their Babies.

    Science.gov (United States)

    Ray, JoAnn; Roloff, Marilee

    1994-01-01

    Describes the Crosswalk program in Spokane, Washington, which provides teenage street mothers with housing, day care, and the opportunity to attend school. Discusses the development of the program, and describes the cases of several typical teenage mothers in the program. (MDM)

  13. Interim Guidance for Oil Heating Equipment Selection for Naval Residential Housing.

    Science.gov (United States)

    1984-01-01

    Minneapolis, Minnesota -16 Des Moines, Iowa -10 Washington, D.C. 14 Raleigh, North Carolina 16 Spokane, Washington -6 Portland, Oregon 17 P.. STEP 3...BURNER C-56 ’a.- MANUAL NO. 17,000/500019-82 INSTALLATION SERVICE AND OPERATING MANUAL ,-RTLI AMERICAN OIL BURNER MODELOE -2 12 6 ,-p. -~ OE-22 I . 6 _ _ OE

  14. 36 CFR 7.55 - Lake Roosevelt National Recreation Area.

    Science.gov (United States)

    2010-07-01

    ... Recreation Area except in the following areas: (i) Crescent Bay Lake. (ii) Kettle River above the Hedlund... persons in the water. (iii) The stretch of the Spokane Arm from 200 feet west of the Two Rivers Marina on... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Lake Roosevelt National...

  15. Eenzaamheid en depressie versterken elkaar (blog)

    NARCIS (Netherlands)

    de Jong Gierveld, J.

    2017-01-01

    Blog 'Eenzaamheid en depressie versterken elkaar' bij Coalitie Erbij, Serie De Kwetsbare Samenleving, 6 februari 2017, www.samentegeneenzaamheid.nl https://www.samentegeneenzaamheid.nl/blog/risicogroepen/eenzaamheid-en-depressie-versterken-elkaar

  16. Dicty_cDB: CHP894 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available iv**ndic*rxlfrsssskkisfrc*rnsfk frnpskenfiikr*scrcl*nl*nftthfpnqlvycr*rc**kpkscrfl*rqik*iksc p*fyii*nsksfqc*...frnpskenfi ikr*scrcl*nl*nftthfpnqlvycr*rc**kpkscrfl*rqik*ikscp*fyii*nsk sfqc***ll

  17. The Contributions of 8P Loss and 8Q Gain to the Malignant Phenotype in Human Prostate Tumors

    National Research Council Canada - National Science Library

    Kant, Rajiv

    2002-01-01

    .... In order to overcome this limitation, the Nl5C6 epithelial and the Nl fibroblastic cell lines were developed through immortalization of explanted human prostate tissue with the HPV and E6 and E7 proteins...

  18. Annotatie bij ABRvS 4 juli 2001 (sluiting café ivm hard drugs)

    NARCIS (Netherlands)

    Brouwer J.G., Jan; Schilder, A.E.

    2002-01-01

    Samenvatting: Dat exploitant van horecabedrijf geen verwijt kan worden gemaakt ten aanzien van aanwezigheid hard drugs, doet niet ter zake. Zie eveneens http://www.openbareorde.nl en http://www.openbareorderecht.nl

  19. Aspects of likelihood inference

    OpenAIRE

    Reid, Nancy

    2013-01-01

    Comment: Published in at http://dx.doi.org/10.3150/12-BEJSP03 the Bernoulli (http://isi.cbs.nl/bernoulli/) by the International Statistical Institute/Bernoulli Society (http://isi.cbs.nl/BS/bshome.htm)

  20. Recidiverende tilfælde af spinocellulær karcinom i necrobiosis lipoidica-sår hos en patient med diabetes

    DEFF Research Database (Denmark)

    Kolovics, Judit; Mattes, Liuba Penova; Andersen, Klaus Ejner

    2015-01-01

    The development of squamous cell carcinoma in chronic and/or non-healing ulcers associated with necrobiosis lipoidica (NL) is rare, but should be considered in diabetic patients. NL is a non-infectious granulomatous degenerative skin disease. The prevalence of NL in diabetic patients is estimated...... to 0,3-1,2%. Awareness of malignant transformation potential within a plaque of NL is crucial for early diagnosis and easy radical treatment. A case from our outpatient diabetes clinic is presented....

  1. Primary neurolymphoma of the tibial nerve: A case report with characteristic MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jung Eun; An, Ji Young; Park, Ji Seon; Ryu, Kyung Nam; Moon, Sung Kyung [Dept. of Radiology, Kyung Hee University Hospital, Seoul (Korea, Republic of)

    2016-11-15

    Primary neurolymphoma (NL) involving the peripheral nervous system is a rare disease that involves the invasion of a nerve or nerve plexus by neoplastic lymphocytes. Although there have been a few reported clinical and pathological cases presenting as primary NL involving the peripheral nerve, the detailed radiological features of NL have not yet been discussed. In this report, we present a case of primary NL involving the tibial nerve and describe the detailed imaging findings on MRI including features used for differential diagnosis.

  2. Matrix models with Penner interaction inspired by interacting ...

    Indian Academy of Sciences (India)

    2015-01-29

    Jan 29, 2015 ... Then the genus is calculated for every structure and plotted as a function of length. The genus distribution function is compared with the prediction from the nonlinear (NL) model. The specific heat and distribution of structure with temperature calculated from the NL model shows that the NL inter-action is ...

  3. Recidiverende tilfælde af spinocellulær karcinom i necrobiosis lipoidica-sår hos en patient med diabetes

    DEFF Research Database (Denmark)

    Kolovics, Judit; Mattes, Liuba Penova; Andersen, Klaus Ejner

    2015-01-01

    The development of squamous cell carcinoma in chronic and/or non-healing ulcers associated with necrobiosis lipoidica (NL) is rare, but should be considered in diabetic patients. NL is a non-infectious granulomatous degenerative skin disease. The prevalence of NL in diabetic patients is estimated...

  4. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2015-01-29

    Jan 29, 2015 ... Then the genus is calculated for every structure and plotted as a function of length. The genus distribution function is compared with the prediction from the nonlinear (NL) model. The specific heat and distribution of structure with temperature calculated from the NL model shows that the NL inter-action is ...

  5. Necrobiosis lipoidica associated with Hashimoto's thyroiditis and positive detection of ANA and ASMA autoantibodies.

    Science.gov (United States)

    Borgia, Francesco; Russo, Giuseppina T; Villari, Provvidenza; Guarneri, Fabrizio; Cucinotta, Domenico; Cannavò, Serafinella P

    2015-07-01

    Necrobiosis lipoidica (NL) is a rare idiopathic cutaneous condition exceptionally associated with autoimmune thyroiditis. We describe the first case of NL, Hashimoto's thyroiditis and positive detection of autoantibodies. Appropriate screening for NL in patients with autoimmune thyroiditis may clarify its real incidence and the existence of a common pathogenetic pathway.

  6. Detection of Co-Infection of Notocactus leninghausii f. cristatus with Six Virus Species in South Korea

    Directory of Open Access Journals (Sweden)

    Chung Hwa Park

    2018-02-01

    Full Text Available Co-infection with two virus species was previously reported in some cactus plants. Here, we showed that Notocactus leninghausii f. cristatus can be co-infected with six different viruses: cactus mild mottle virus (CMMoV-Nl, cactus virus X (CVX-Nl, pitaya virus X (PiVX-Nl, rattail cactus necrosis-associated virus (RCNaV-Nl, schlumbergera virus X (SchVX-Nl, and zygocactus virus X (ZyVX-Nl. The coat protein sequences of these viruses were compared with those of previously reported viruses. CMMoV-Nl, CVX-Nl, PiVX-Nl, RCNaV-Nl, SchVX-Nl, and ZyVX-Nl showed the greatest nucleotide sequence homology to CMMoV-Kr (99.8% identity, GenBank accession NC_011803, CVX-Jeju (77.5% identity, GenBank accession LC12841, PiVX-P37 (98.4% identity, GenBank accession NC_024458, RCNaV (99.4% identity, GenBank accession NC_016442, SchVX-K11 (95.7% identity, GenBank accession NC_011659, and ZyVX-B1 (97.9% identity, GenBank accession NC_006059, respectively. This study is the first report of co-infection with six virus species in N. leninghausii f. cristatus in South Korea.

  7. Detection of Co-Infection ofNotocactus leninghausiif.cristatuswith Six Virus Species in South Korea.

    Science.gov (United States)

    Park, Chung Hwa; Song, Eun Gyeong; Ryu, Ki Hyun

    2018-02-01

    Co-infection with two virus species was previously reported in some cactus plants. Here, we showed that Notocactus leninghausii f. cristatus can be co-infected with six different viruses: cactus mild mottle virus (CMMoV)-Nl, cactus virus X (CVX)-Nl, pitaya virus X (PiVX)-Nl, rattail cactus necrosis-associated virus (RCNaV)-Nl, schlumbergera virus X (SchVX)-Nl, and zygocactus virus X (ZyVX)-Nl. The coat protein sequences of these viruses were compared with those of previously reported viruses. CMMoV-Nl, CVX-Nl, PiVX-Nl, RCNaV-Nl, SchVX-Nl, and ZyVX-Nl showed the greatest nucleotide sequence homology to CMMoV-Kr (99.8% identity, GenBank accession NC_011803), CVX-Jeju (77.5% identity, GenBank accession LC12841), PiVX-P37 (98.4% identity, GenBank accession NC_024458), RCNaV (99.4% identity, GenBank accession NC_016442), SchVX-K11 (95.7% identity, GenBank accession NC_011659), and ZyVX-B1 (97.9% identity, GenBank accession NC_006059), respectively. This study is the first report of co-infection with six virus species in N. leninghausii f. cristatus in South Korea.

  8. Biochemical methane potential and anaerobic biodegradability of non-herbaceous and herbaceous phytomass in biogas production

    DEFF Research Database (Denmark)

    Triolo, Jin Mi; Pedersen, Lene; Qu, Haiyan

    2012-01-01

    of herbaceous garden plants (332.7 CH4 NL kg VS1) was high, although lower than that of energy crops (400–475 CH4 NL kg VS1). Herbaceous wild plants from natural grassland contained most lignocelluloses, leading to relatively low BMP (214.0 CH4 NL kg VS1). Non-herbaceous phytomass had a high degree...

  9. Amyloid and metabolic positron emission tomography imaging of cognitively normal adults with Alzheimer's parents

    DEFF Research Database (Denmark)

    Mosconi, Lisa; Rinne, Juha O; Tsui, Wai H

    2013-01-01

    emission tomography (PET) with (11)C-Pittsburgh compound B (PiB) and 18F-fluoro-2-deoxy-d-glucose (FDG). These included 19 NL with a maternal history (MH), 12 NL with a paternal history (PH), and 16 NL with negative family history of AD (NH). Automated regions of interest, statistical parametric mapping......This study examines the relationship between fibrillar beta-amyloid (Aβ) deposition and reduced glucose metabolism, a proxy for neuronal dysfunction, in cognitively normal (NL) individuals with a parent affected by late-onset Alzheimer's disease (AD). Forty-seven 40-80-year-old NL received positron...

  10. Resident Fish Stock Status above Chief Joseph and Grand Coulee Dams; 2002-2003 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Connor, Jason M. (Kalispel Tribe of Indians, Usk, WA); McLellan, Jason G. (Washington Department of Fish and Wildlife); Butler, Chris (Spokane Tribe of Indians, Wellpinit, WA)

    2006-02-01

    initial year of the project (1997) identified the need for a central data storage and analysis facility, coordination with the StreamNet project, compilation of Blocked Area fisheries information, and a report on the ecological condition of the Spokane River System. These needs were addressed in 1998 by acquiring a central location with a data storage and analysis system, coordinating a pilot project with StreamNet, compiling fisheries distribution data throughout the Blocked Area, identifying data gaps based on compiled information, and researching the ecological condition of the Spokane River. In order to ensure that any additional information collected throughout the life of this project will be easily stored and manipulated by the central storage facility, it was necessary to develop standardized methodologies between the JSAP fisheries managers. Common collection and analytical methodologies were developed in 1999. The project began addressing identified data gaps throughout the Blocked Area in 1999. Data collection of established projects and a variety of newly developed sampling projects are ongoing. Projects developed and undertaken by JSAP fisheries managers include investigations of the Pend Orielle River and its tributaries, the Little Spokane River and its tributaries, and water bodies within and near the Spokane Indian Reservation. Migration patterns of adfluvial and reservoir fish in Box Canyon Reservoir and its tributaries, a baseline assessment of Boundary Reservoir and its tributaries, ecological assessment of mountain lakes in Pend Oreille County, and assessments of streams and lakes on the Spokane Indian Reservation were completed by 2001. Assessments of the Little Spokane River and its tributaries, Spokane River below Spokane Falls, tributaries to the Pend Oreille River, small lakes in Pend Oreille County, WA, and water bodies within and near the Spokane Indian Reservation were conducted in 2002 and 2003. This work was done in accordance with the scope

  11. Resident Fish Stock above Chief Joseph and Grand Coulee Dams; 2003-2004 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Connor, Jason M. (Kalispel Tribe of Indians, Usk, WA); McLellan, Jason G. (Washington Department of Fish and Wildlife, Olympia, WA); Butler, Chris (Spokane Tribe of Indians, Wellpinit, WA)

    2005-11-01

    initial year of the project (1997) identified the need for a central data storage and analysis facility, coordination with the StreamNet project, compilation of Blocked Area fisheries information, and a report on the ecological condition of the Spokane River System. These needs were addressed in 1998 by acquiring a central location with a data storage and analysis system, coordinating a pilot project with StreamNet, compiling fisheries distribution data throughout the Blocked Area, identifying data gaps based on compiled information, and researching the ecological condition of the Spokane River. In order to ensure that any additional information collected throughout the life of this project will be easily stored and manipulated by the central storage facility, it was necessary to develop standardized methodologies between the JSAP fisheries managers. Common collection and analytical methodologies were developed in 1999. The project began addressing identified data gaps throughout the Blocked Area in 1999. Data collection of established projects and a variety of newly developed sampling projects are ongoing. Projects developed and undertaken by JSAP fisheries managers include investigations of the Pend Orielle River and its tributaries, the Little Spokane River and its tributaries, and water bodies within and near the Spokane Indian Reservation. Migration patterns of adfluvial and reservoir fish in Box Canyon Reservoir and its tributaries, a baseline assessment of Boundary Reservoir and its tributaries, ecological assessment of mountain lakes in Pend Oreille County, and assessments of streams and lakes on the Spokane Indian Reservation were completed by 2001. Assessments of the Little Spokane River and its tributaries, Spokane River below Spokane Falls, tributaries to the Pend Oreille River, small lakes in Pend Oreille County, WA, and water bodies within and near the Spokane Indian Reservation were conducted in 2002 and 2003. This work was done in accordance with the scope

  12. Longitudinal Changes in Young Children’s 0-100 to 0-1000 Number-Line Error Signatures

    Directory of Open Access Journals (Sweden)

    Robert A. Reeve

    2015-05-01

    Full Text Available We use a latent difference score (LDS model to examine changes in young children’s number-line (NL error signatures (errors marking numbers on a NL over 18 months. A LDS model (1 overcomes some of the inference limitations of analytic models used in previous research, and in particular (2 provides a more reliable test of hypotheses about the meaning and significance of changes in NL error signatures over time and task. The NL error signatures of 217 6-year-olds’ (on test occasion one were assessed three times over 18 months, along with their math ability on two occasions. On the first occasion (T1 children completed a 0–100 NL task; on the second (T2 a 0–100 NL and a 0–1000 NL task; on the third (T3 occasion a 0–1000 NL task. On the third and fourth occasions (T3 and T4, children completed mental calculation tasks. Although NL error signatures changed over time, these were predictable from other NL task error signatures, and predicted calculation accuracy at T3, as well as changes in calculation between T3 and T4. Multiple indirect effects (change parameters showed that associations between initial NL error signatures (0–100 NL and later mental calculation ability were mediated by error signatures on the 0–1000 NL task. The pattern of findings from the LDS model highlight the value of identifying direct and indirect effects in characterizing changing relationships in cognitive representations over task and time. Substantively, they support the claim that children’s NL error signatures generalize over task and time and thus can be used to predict math ability.

  13. Glass dissolution at 20, 40, 70 and 90 C: Short-term effects of solution chemistry and long-term Na release

    International Nuclear Information System (INIS)

    Bakel, A.J.; Ebert, W.L.; Strachan, D.M.

    1996-01-01

    The corrosion behavior of a borosilicate glass containing 20 mass 5 Na 2 O was assessed using static dissolution tests. This glass (LD6-5412) is representative of high Na glasses that may be used to stabilize Hanford low-level radioactive waste. The normalized mass loss (NL) decreases as NL(Na) ∼ NL(B) > NL(Si) in 20 and 40 C for tests conducted at glass surface area to leachant volume (S/V) ratio of 10 m -1 , and decreases as NL(Na) > NL(B) ∼ NL(Si) in 90 C tests conducted at 10 m -1 and in all tests conducted at higher S/V. The difference in the corrosion behavior is probably caused by the influence of dissolved glass components in the leachates. The NL(Na) is greater than the NL(B) or NL(Si) in all the tests conducted. Results from long-term tests at 2,000 m -1 show that the preferential release of Na persists for longer than one year at all temperatures and indicate that Na is released from this glass by an ion exchange process

  14. Chitin deacetylase family genes in the brown planthopper, Nilaparvata lugens (Hemiptera: Delphacidae).

    Science.gov (United States)

    Xi, Y; Pan, P-L; Ye, Y-X; Yu, B; Zhang, C-X

    2014-12-01

    Chitin deacetylases (CDAs) are enzymes required for one of the pathways of chitin degradation, in which chitosan is produced by the deacetylation of chitin. Bioinformatic investigations with genomic and transcriptomic databases identified four genes encoding CDAs in Nilaparvata lugens (NlCDAs). Phylogenetic analysis showed that insect CDAs were clustered into five major groups. Group I, III and IV CDAs are found in all insect species, whereas the pupa-specific group II and gut-specific group V CDAs are not found in the plant-sap/blood-sucking hemimetabolous species from Hemiptera and Anoplura. The developmental and tissue-specific expression patterns of four NlCDAs revealed that NlCDA3 was a gut-specific CDA, with high expression at all developmental stages; NlCDA1, NlCDA2 and NlCDA4 were highly expressed in the integument and peaked periodically during every moulting, which suggests their roles in chitin turnover of the insect old cuticle. Lethal phenotypes of cuticle shedding failure and high mortality after the injection of double-stranded RNAs (dsRNAs) for NlCDA1, NlCDA2 and NlCDA4 provide further evidence for their functions associated with moulting. No observable morphological and internal structural abnormality was obtained in insects treated with dsRNA for gut-specific NlCDA3. © 2014 The Royal Entomological Society.

  15. Axial zero-field splitting in mononuclear Co(ii) 2-N substituted N-confused porphyrin: Co(2-NC3H5-21-Y-CH2C6H4CH3-NCTPP)Cl (Y = o, m, p) and Co(2-NC3H5-21-CH2C6H5-NCTPP)Cl.

    Science.gov (United States)

    Lai, Ya-Yuan; Chang, Yu-Chang; Chen, Jyh-Horung; Wang, Shin-Shin; Tung, Jo-Yu

    2016-03-21

    The inner C-benzyl- and C-o-xylyl (or m-xylyl, p-xylyl)-substituted cobalt(ii) complexes of a 2-N-substituted N-confused porphyrin were synthesized from the reaction of 2-NC3H5NCTPPH (1) and CoCl2·6H2O in toluene (or o-xylene, m-xylene, p-xylene). The crystal structures of diamagnetic chloro(2-aza-2-allyl-5,10,15,20-tetraphenyl-21-hydrogen-21-carbaporphyrinato-N,N',N'')zinc(ii) [Zn(2-NC3H5-21-H-NCTPP)Cl; 3 ] and paramagnetic chloro(2-aza-2-allyl-5,10,15,20-tetraphenyl-21-benzyl-21-carbaporphyrinato-N,N',N'')cobalt(ii) [Co(2-NC3H5-21-CH2C6H5NCTPP)Cl; 7], and chloro(2-aza-2-allyl-5,10,15,20-tetraphenyl-21-Y-xylyl-21-carbaporphyrinato-N,N',N'')cobalt(ii) [Co(2-NC3H5-21-Y-CH2C6H4CH3NCTPP)Cl] [Y = o (8), m (9), p (10)] were determined. The coordination sphere around the Zn(2+) (or Co(2+)) ion in 3 (or 7-10) is a distorted tetrahedron (DT). The free energy of activation at the coalescence temperature Tc for the exchange of phenyl ortho protons o-H (26) with o-H (22) in 3 in a CDCl3 solvent is found to be ΔG = 61.4 kJ mol(-1) through (1)H NMR temperature-dependent measurements. The axial zero-field splitting parameter |D| was found to vary from 35.6 cm(-1) in 7 (or 30.7 cm(-1) in 8) to 42.0 cm(-1) in 9 and 46.9 cm(-1) in 10 through paramagnetic susceptibility measurements. The magnitude of |D| can be related to the coordination sphere at the cobalt sites.

  16. The 12th Annual International Meeting on Simulation Healthcare (IMSH) 2012

    Science.gov (United States)

    2012-03-01

    Hawaii Honolulu HI USA John Berger MD Children’s National Medical Center Washington DC USA Cassandra Bergero RN FNP CNS Lucile Packard...Bigham DNP RN FNP -BC University of Alabama Tuscaloosa AL USA Lisa Bilich BSDH MSEd Eastern Washington University Spokane WA USA Peter Billas MD...of Miami Miller School of Medicine Miami FL USA Barbara DeVoe DNP FNP -BC North Shore Long Island Jewish Center of Innovation Lake Success NY

  17. South Channel Dam Rehabilitation Project - Successfully Addressing Dam Rehabilitation Challenges

    OpenAIRE

    Graeser, M. D.; Jensen, M. C.

    2016-01-01

    The Post Falls South Channel Dam is located on the Spokane River in Post Falls, Idaho. The concrete gravity dam was constructed in 1906 and was recently rehabilitated. The rehabilitation project included several design elements; the primary objectives were the replacement of the six spillway gates and hoists and significant rehabilitation of the concrete. The South Channel Dam rehabilitation encountered several challenges due to the age and condition of the existing structure, the large scale...

  18. Letters to the Editor

    Science.gov (United States)

    1998-07-01

    A Local Physics Teachers Day: an amateur model for INSET Philip Britton Head of Physics, Leeds Grammar School Secretary, loP Education Group Determining a Slinky's spring constant Eric Kincanon Gonzaga University, Spokane, WA 99258-0051, USA Word Juxtapoz: an interesting tool for promoting physics education R Subramaniam, N K Goh and L S Chia Singapore Science Centre, Science Centre Road, Singapore 609081 Division of Chemistry, Nanyang Technological University, 469 Bukit Timah Road, Singapore 259756

  19. Blue Creek Winter Range: Wildlife Mitigation Project

    International Nuclear Information System (INIS)

    1994-01-01

    This preliminary Environmental Assessment examines the potential environmental effects of securing land and conducting wildlife habitat enhancement and long term management activities within the boundaries of the Spokane Indian Reservation. Four proposed activities are analyzed: Habitat protection; Habitat enhancement; Operation and maintenance; and Monitoring and evaluation. The proposed action is intended to meet the need for mitigation of wildlife and wildlife habitat adversely affected by the construction of Grand Coulee Dam and its reservoir

  20. Study on the Effect of Wing Bud Chitin Metabolism and Its Developmental Network Genes in the Brown Planthopper, Nilaparvata lugens, by Knockdown of TRE Gene

    Directory of Open Access Journals (Sweden)

    Lu Zhang

    2017-09-01

    Full Text Available The brown planthopper, Nilaparvata lugens is one of the most serious pests of rice, and there is so far no effective way to manage this pest. However, RNA interference not only can be used to study gene function, but also provide potential opportunities for novel pest management. The development of wing plays a key role in insect physiological activities and mainly involves chitin. Hence, the regulating role of trehalase (TRE genes on wing bud formation has been studied by RNAi. In this paper, the activity levels of TRE and the contents of the two sugars trehalose and glucose were negatively correlated indicating the potential role of TRE in the molting process. In addition, NlTRE1-1 and NlTRE2 were expressed at higher levels in wing bud tissue than in other tissues, and abnormal molting and wing deformity or curling were noted 48 h after the insect was injected with any double-stranded TRE (dsTRE, even though different TREs have compensatory functions. The expression levels of NlCHS1b, NlCht1, NlCht2, NlCht6, NlCht7, NlCht8, NlCht10, NlIDGF, and NlENGase decreased significantly 48 h after the insect was injected with a mixture of three kinds of dsTREs. Similarly, the TRE inhibitor validamycin can inhibit NlCHS1 and NlCht gene expression. However, the wing deformity was the result of the NlIDGF, NlENGase, NlAP, and NlTSH genes being inhibited when a single dsTRE was injected. These results demonstrate that silencing of TRE gene expression can lead to wing deformities due to the down-regulation of the AP and TSH genes involved in wing development and that the TRE inhibitor validamycin can co-regulate chitin metabolism and the expression of wing development-related genes in wing bud tissue. The results provide a new approach for the prevention and management of N. lugens.

  1. Study on the Effect of Wing Bud Chitin Metabolism and Its Developmental Network Genes in the Brown Planthopper, Nilaparvata lugens, by Knockdown of TRE Gene.

    Science.gov (United States)

    Zhang, Lu; Qiu, Ling-Yu; Yang, Hui-Li; Wang, Hui-Juan; Zhou, Min; Wang, Shi-Gui; Tang, Bin

    2017-01-01

    The brown planthopper, Nilaparvata lugens is one of the most serious pests of rice, and there is so far no effective way to manage this pest. However, RNA interference not only can be used to study gene function, but also provide potential opportunities for novel pest management. The development of wing plays a key role in insect physiological activities and mainly involves chitin. Hence, the regulating role of trehalase (TRE) genes on wing bud formation has been studied by RNAi. In this paper, the activity levels of TRE and the contents of the two sugars trehalose and glucose were negatively correlated indicating the potential role of TRE in the molting process. In addition, NlTRE1-1 and NlTRE2 were expressed at higher levels in wing bud tissue than in other tissues, and abnormal molting and wing deformity or curling were noted 48 h after the insect was injected with any double-stranded TRE ( dsTRE ), even though different TREs have compensatory functions. The expression levels of NlCHS1b, NlCht1, NlCht2, NlCht6, NlCht7, NlCht8, NlCht10, NlIDGF , and NlENGase decreased significantly 48 h after the insect was injected with a mixture of three kinds of dsTREs . Similarly, the TRE inhibitor validamycin can inhibit NlCHS1 and NlCht gene expression. However, the wing deformity was the result of the NlIDGF, NlENGase, NlAP , and NlTSH genes being inhibited when a single dsTRE was injected. These results demonstrate that silencing of TRE gene expression can lead to wing deformities due to the down-regulation of the AP and TSH genes involved in wing development and that the TRE inhibitor validamycin can co-regulate chitin metabolism and the expression of wing development-related genes in wing bud tissue. The results provide a new approach for the prevention and management of N. lugens .

  2. Water Budgets for Coeur d'Alene Lake, Idaho, Water Years 2000-2005

    Science.gov (United States)

    Maupin, Molly A.; Weakland, Rhonda J.

    2009-01-01

    The U.S. Geological Survey, in cooperation with the Idaho Department of Water Resources, calculated annual water budgets and a mean annual water budget for Coeur d'Alene Lake, Idaho, for water years 2000 through 2005. Mean annual inflow to Coeur d'Alene Lake, including precipitation, was about 167,110 million cubic feet. Mean annual outflow, including evaporation, but excluding wastewater effluent to the Spokane River, was about 167,850 million cubic feet. The amount of water lost from Coeur d'Alene Lake and the Spokane River to the Spokane Valley-Rathdrum Prairie aquifer was estimated at 7,250 million cubic feet. Mean annual precipitation into Coeur d'Alene Lake was 3,267 million cubic feet, which exceeded mean annual evaporation of 2,483 million cubic feet. Withdrawals directly from the lake and from wells within a 1,000 foot buffer of the lakeshore for domestic and municipal water uses were reported. However, only the estimate for the consumptive use part of the withdrawals, 265 million cubic feet, was considered in the budget. Mean annual change in lake storage resulted in a net loss of about 49 million cubic feet. The mean annual residual value was about -8,310 million cubic feet.

  3. DESENVOLVIMENTO DA SOJA COM APLICAÇÕES DE HORMÔNIOS EM DIFERENTES DENSIDADES DE CULTIVO

    Directory of Open Access Journals (Sweden)

    Sydney Antonio Frehner Kavalco

    2014-12-01

    NL1, NL2, NL3 e MMG. Ausência de interação foi evidenciada para os caracteres AH e NLH. A utilização de hormônios na dose de 750 ml ha-1 aplicado no estádio R5 da soja contribuiu para o incremento dos caracteres NLH, NRR, NR, CR, NL1, NL2 quando utilizou-se a densidade de 110.000 plantas ha-1. O rendimento de grãos não foi influenciado pelas concentrações de hormônios, mas a densidade de cultivo de 245.000 plantas ha-1 evidenciou superioridade para este caráter. Efeitos diretos positivos ao rendimento de grãos foram revelados através dos caracteres NLH e MMG, e negativos por meio de NLR, NRH, NRR e NL3.

  4. Sentinel Node in Oral Cancer

    DEFF Research Database (Denmark)

    Tartaglione, Girolamo; Stoeckli, Sandro J; de Bree, Remco

    2016-01-01

    localization and estimated SN depth more efficiently. After pathological examination, 9.9% of the SN excised (138 of 1398 SNs) showed metastases. The first neck level (NL) containing SN+ was NL I in 28.6%, NL IIa in 44.8%, NL IIb in 2.8%, NL III in 17.1%, and NL IV in 6.7% of positive patients. Approximately...... 96% of positive SNs were localized in the first and second lymphatic basin visualized using lymphoscintigraphy. After neck dissection, the SN+ was the only lymph node containing metastasis in approximately 80% of patients. CONCLUSIONS: Best results were observed using a dynamic scan in combination......PURPOSE: Nuclear imaging plays a crucial role in lymphatic mapping of oral cancer. This evaluation represents a subanalysis of the original multicenter SENT trial data set, involving 434 patients with T1-T2, N0, and M0 oral squamous cell carcinoma. The impact of acquisition techniques, tracer...

  5. First constraints on the running of non-Gaussianity.

    Science.gov (United States)

    Becker, Adam; Huterer, Dragan

    2012-09-21

    We use data from the Wilkinson Microwave Anisotropy probe temperature maps to constrain a scale-dependent generalization of the popular "local" model for primordial non-Gaussianity. In the model where the parameter f(NL) is allowed to run with scale k, f(NL)(k) = f*(NL) (k/k(piv))(n)(fNL), we constrain the running to be n(f)(NL) = 0.30(-1.2)(+1.9) at 95% confidence, marginalized over the amplitude f*(NL). The constraints depend somewhat on the prior probabilities assigned to the two parameters. In the near future, constraints from a combination of Planck and large-scale structure surveys are expected to improve this limit by about an order of magnitude and usefully constrain classes of inflationary models.

  6. Ran Involved in the Development and Reproduction Is a Potential Target for RNA-Interference-Based Pest Management in Nilaparvata lugens.

    Directory of Open Access Journals (Sweden)

    Kai-Long Li

    Full Text Available Ran (RanGTPase in insects participates in the 20-hydroxyecdysone signal transduction pathway in which downstream genes, FTZ-F1, Krüppel-homolog 1 (Kr-h1 and vitellogenin, are involved. A putative Ran gene (NlRan was cloned from Nilaparvata lugens, a destructive phloem-feeding pest of rice. NlRan has the typical Ran primary structure features that are conserved in insects. NlRan showed higher mRNA abundance immediately after molting and peaked in newly emerged female adults. Among the examined tissues ovary had the highest transcript level, followed by fat body, midgut and integument, and legs. Three days after dsNlRan injection the NlRan mRNA abundance in the third-, fourth-, and fifth-instar nymphs was decreased by 94.3%, 98.4% and 97.0%, respectively. NlFTZ-F1 expression levels in treated third- and fourth-instar nymphs were reduced by 89.3% and 23.8%, respectively. In contrast, NlKr-h1 mRNA levels were up-regulated by 67.5 and 1.5 folds, respectively. NlRan knockdown significantly decreased the body weights, delayed development, and killed >85% of the nymphs at day seven. Two apparent phenotypic defects were observed: (1 Extended body form, and failed to molt; (2 The cuticle at the notum was split open but cannot completely shed off. The newly emerged female adults from dsNlRan injected fifth-instar nymphs showed lower levels of NlRan and vitellogenin, lower weight gain and honeydew excretion comparing with the blank control, and no offspring. Those results suggest that NlRan encodes a functional protein that was involved in development and reproduction. The study established proof of concept that NlRan could serve as a target for dsRNA-based pesticides for N. lugens control.

  7. Confocal Analysis of Nuclear Lamina Behavior during Male Meiosis and Spermatogenesis in Drosophila melanogaster.

    Directory of Open Access Journals (Sweden)

    Fabiana Fabbretti

    Full Text Available Lamin family proteins are structural components of a filamentous framework, the nuclear lamina (NL, underlying the inner membrane of nuclear envelope. The NL not only plays a role in nucleus mechanical support and nuclear shaping, but is also involved in many cellular processes including DNA replication, gene expression and chromatin positioning. Spermatogenesis is a very complex differentiation process in which each stage is characterized by nuclear architecture dramatic changes, from the early mitotic stage to the sperm differentiation final stage. Nevertheless, very few data are present in the literature on the NL behavior during this process. Here we show the first and complete description of NL behavior during meiosis and spermatogenesis in Drosophila melanogaster. By confocal imaging, we characterized the NL modifications from mitotic stages, through meiotic divisions to sperm differentiation with an anti-laminDm0 antibody against the major component of the Drosophila NL. We observed that continuous changes in the NL structure occurred in parallel with chromatin reorganization throughout the whole process and that meiotic divisions occurred in a closed context. Finally, we analyzed NL in solofuso meiotic mutant, where chromatin segregation is severely affected, and found the strict correlation between the presence of chromatin and that of NL.

  8. Dicty_cDB: CFJ154 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ACCAA sequence update 2001.11.22 Translated Amino Acid sequence vkccstinptfmink*K...qviesitinr*f**nl*rlfhlvyhllsit*wlylrgipicxekwdpv isifit Frame B: vkccstinptfmink*KRREKKMNVKEMDFNDLSNKSNQIINR

  9. Broad sustainability versus sustainability

    International Nuclear Information System (INIS)

    Hueting, R.; Reijnders, L.

    2002-01-01

    The notion sustainability has many definitions and interpretations, which are not always in favor of the development of sustainability. Therefore, a narrow definition of sustainability is required [nl

  10. Statistical nature of non-Gaussianity from cubic order primordial perturbations: CMB map simulations and genus statistic

    International Nuclear Information System (INIS)

    Chingangbam, Pravabati; Park, Changbom

    2009-01-01

    We simulate CMB maps including non-Gaussianity arising from cubic order perturbations of the primordial gravitational potential, characterized by the non-linearity parameter g NL . The maps are used to study the characteristic nature of the resulting non-Gaussian temperature fluctuations. We measure the genus and investigate how it deviates from Gaussian shape as a function of g NL and smoothing scale. We find that the deviation of the non-Gaussian genus curve from the Gaussian one has an antisymmetric, sine function like shape, implying more hot and more cold spots for g NL > 0 and less of both for g NL NL and also exhibits mild increase as the smoothing scale increases. We further study other statistics derived from the genus, namely, the number of hot spots, the number of cold spots, combined number of hot and cold spots and the slope of the genus curve at mean temperature fluctuation. We find that these observables carry signatures of g NL that are clearly distinct from the quadratic order perturbations, encoded in the parameter f NL . Hence they can be very useful tools for distinguishing not only between non-Gaussian temperature fluctuations and Gaussian ones but also between g NL and f NL type non-Gaussianities

  11. Dicty_cDB: AFH843 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available LYLASLLFLITLYLSPTFGWGGGRDXEXHRSEYTCKSDRSCAYL PFVSCXGKKEFFCVNRDHRNCCDDLSCAKNTRTGEIFEIXSSCKPHRDFVPYHSPNTTTC ES...kxkknnnenfifsfsfifnyiisitnfwxgwwqrlxxssfriym*ir*klcif ticimlx*eriflc*s*s*kll**fimc*khenw*nl*dxvkl*tt*rfctisf...SDRSCAYL PFVSCXGKKEFFCVNRDHRNCCDDLSCAKNTRTGEIFEIXSSCKPHRDFVPYHSPNTTTC ESLGCEARGXE

  12. Phylogeny of not-yet-cultured spirochetes from termite guts

    DEFF Research Database (Denmark)

    Paster, B.J.; Dewhirst, F.E.; Cooke, S.M.

    1996-01-01

    products were cloned into Escherichia coli, Clones were screened with a spirochete-specific DNA probe, Analysis of 1,410 base positions of the 16S rDNA insert from one spirochete clone, designated NL1, supported its assignment to the genus Treponema, with average interspecies similarities of ca. 85...... of 16S rRNA sequence comparisons and individual base signatures, clones NL1 and MDS1 clearly represent two novel species of Treponema, although specific epithets have not yet been proposed. The gross morphology of NL1 was determined from in situ hybridization experiments with an NL1-specific...

  13. Molecular characterization, expression analysis and RNAi knock-down of elongation factor 1α and 1γ from Nilaparvata lugens and its yeast-like symbiont.

    Science.gov (United States)

    Wang, W X; Zhu, T H; Li, K L; Chen, L F; Lai, F X; Fu, Q

    2017-06-01

    In the present paper, four cDNAs encoding the alpha and gamma subunits of elongation factor 1 (EF-1) were cloned and sequenced from Nilaparvata lugens, named NlEF-1α, NlEF-1γ, and its yeast-like symbiont (YLS), named YsEF-1α and YsEF-1γ, respectively. Comparisons with sequences from other species indicated a greater conservation for EF-1α than for EF-1γ. NlEF-1α has two identical copies. The deduced amino acid sequence homology of NlEF-1α and NlEF-1γ is 96 and 64%, respectively, compared with Homalodisca vitripennis and Locusta migratoria. The deduced amino acid sequence homology of YsEF-1α and YsEF-1γ is 96 and 74%, respectively, compared with Metarhizium anisopliae and Ophiocordyceps sinensis. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) analysis revealed that the expression level of NlEF-1α and NlEF-1γ mRNA in hemolymph, ovary, fat body and salivary glands were higher than the midgut and leg tissue. YsEF-1α and YsEF-1γ was highly expressed in fat body. The expression level of NlEF-1α was higher than that of NlEF-1γ. Through RNA interference (RNAi) of the two genes, the mortality of nymph reached 92.2% at the 11th day after treatment and the ovarian development was severely hindered. The RT-qPCR analysis verified the correlation between mortality, sterility and the down-regulation of the target genes. The expression and synthesis of vitellogenin (Vg) protein in insects injected with NlEF-1α and NlEF-1γ double-stranded RNA (dsRNA) was significantly lower than control groups. Attempts to knockdown the YsEF-1 genes in the YLS was unsuccessful. However, the phenotype of N. lugens injected with YsEF-1α dsRNA was the same as that injected with NlEF-1α dsRNA, possibly due to the high similarity (up to 71.9%) in the nucleotide sequences between NlEF-1α and YsEF-1α. We demonstrated that partial silencing of NlEF-1α and NlEF-1γ genes caused lethal and sterility effect on N. lugens. NlEF-1γ shares low identity with that of

  14. Resident Fish Stock above Chief Joseph and Grand Coulee Dams; 2002 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Connor, Jason M. (Kalispel Department of Natural Resources, Usk, WA); McLellan, Jason G. (Washington Department of Fish and Wildlife, Spokane, WA); Butler, Chris (Spokane Tribe of Indians, Department of Natural Resources, Wellpinit, WA)

    2003-09-01

    . The initial year of the project (1997) identified the need for a central data storage and analysis facility, coordination with the StreamNet project, compilation of Blocked Area fisheries information, and a report on the ecological condition of the Spokane River System. These needs were addressed in 1998 by acquiring a central location with a data storage and analysis system, coordinating a pilot project with StreamNet, compiling fisheries distribution data throughout the Blocked Area, identifying data gaps based on compiled information, and researching the ecological condition of the Spokane River. In order to ensure that any additional information collected throughout the life of this project will be easily stored and manipulated by the central storage facility, it was necessary to develop standardized methodologies between the JSAP fisheries managers. Common collection and analytical methodologies were developed in 1999. In 1999, 2000, and 2001 the project began addressing some of the identified data gaps throughout the Blocked Area. Data collection of established projects and a variety of newly developed sampling projects are ongoing. Projects developed and undertaken by JSAP fisheries managers include investigations of the Pend Orielle River and its tributaries, the Little Spokane River and its tributaries, and water bodies within and near the Spokane Indian Reservation. Migration patterns of adfluvial and reservoir fish in Box Canyon Reservoir and its tributaries, a baseline assessment of Boundary Reservoir and its tributaries, ecological assessment of mountain lakes in Pend Oreille County, and assessments of streams and lakes on the Spokane Indian Reservation were completed by 2001. Assessments of the Little Spokane River and its tributaries, tributaries to the Pend Oreille River, small lakes in Pend Oreille County, WA, and water bodies within and near the Spokane Indian Reservation were conducted in 2002. This work was done in accordance with the scope of work

  15. Resident Fish Stock Status above Chief Joseph and Grand Coulee Dams; 2001 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Connor, Jason M. (Kalispell Department of Natural Resources, Usk, WA); McLellan, Jason G. (Washington Department of Fish and Wildlife, Spokane, WA); O' Connor, Dick (Washington Department of Fish and Wildlife, Olympia, WA)

    2003-01-01

    (1998). The initial year of the project (1997) identified the need for a central data storage and analysis facility, coordination with the StreamNet project, compilation of Blocked Area fisheries information, and a report on the ecological condition of the Spokane River System. These needs were addressed in 1998 by acquiring a central location with a data storage and analysis system, coordinating a pilot project with StreamNet, compiling fisheries distribution data throughout the Blocked Area, identifying data gaps based on compiled information, and researching the ecological condition of the Spokane River. In order to ensure that any additional information collected throughout the life of this project will be easily stored and manipulated by the central storage facility, it was necessary to develop standardized methodologies between the JSAP fisheries managers. Common collection and analytical methodologies were developed in 1999. In 1999, 2000, and 2001 the project began addressing some of the identified data gaps throughout the Blocked Area. Data collection of established projects and a variety of newly developed sampling projects are ongoing. Projects developed and undertaken by JSAP fisheries managers include investigations of the Pend Orielle River and its tributaries, the Little Spokane River and its tributaries, and water bodies within and near the Spokane Indian Reservation. Migration patterns of adfluvial and reservoir fish in Box Canyon Reservoir and its tributaries, a baseline assessment of Boundary Reservoir and its tributaries, ecological assessment of mountain lakes in Pend Oreille County, and assessments of seven streams and four lakes on the Spokane Indian Reservation were completed by 2000. Assessments of the Little Spokane River and its tributaries, tributaries to the Pend Oreille River, small lakes in southern Pend Oreille County, and water bodies within and near the Spokane Indian Reservation were conducted in 2001. This work was done in accordance

  16. New DigiGuide. Zero-energy building; Nieuwe DigiGids. Energieneutraal Bouwen

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-01-15

    NL Agency ordered for a study on the aspects of zero-energy ('energy-neutral') building and listed and discussed briefly the latest developments [Dutch] Agentschap NL heeft onderzoek laten uitvoeren naar (aspecten van) energieneutraal bouwen en heeft de actuele ontwikkelingen vastgelegd.

  17. A method to customize population-specific arrays for genome-wide association testing

    NARCIS (Netherlands)

    Ehli, E.A.; Abdellaoui, A.; Fedko, I.O.; Grieser, C.; Nohzadeh-Malakshah, S.; Willemsen, G.; de Geus, E.J.C.; Boomsma, D.I.; Davies, G.E.; Hottenga, J.J.

    2017-01-01

    As an example of optimizing population-specific genotyping assays using a whole-genome sequence reference set, we detail the approach that followed to design the Axiom-NL array which is characterized by an improved imputation backbone based on the Genome of the Netherlands (GoNL) reference sequence

  18. Richtlijn 'Behandeling van het mammacarcinoom 2008' (herziening)

    NARCIS (Netherlands)

    Struikmans, H.; Nortier, J. W. R.; Rutgers, E. J. Th; Zonderland, H. M.; Bontenbal, M.; Elkhuizen, P. H. M.; van Tienhoven, G.; Tjan-Heijnen, V. C. G.; van Vegchel, T.; Tuut, M. K.; Benraadt, J.

    2008-01-01

    The Dutch evidence-based guideline 'Treatment of breast cancer' has been revised, and integrated with the guideline 'Screening for and diagnosis of breast cancer'. The guideline can be found on www. oncoline.nl and on www.cbo.nl. The Internet programme 'Adjuvant!' (www.adjuvantonline.com) can be

  19. Collective Cultural Memory as a TV Guide : ‘Living’ History and Nostalgia on the Digital Television Platform

    NARCIS (Netherlands)

    Hagedoorn, Berber

    2017-01-01

    Collective Cultural Memory as a TV Guide: “Living” History and Nostalgia on the Digital Television Platform Berber Hagedoorn University of Groningen (NL) E-mail: b.hagedoorn@rug.nl Abstract: Modern audiences engage with representations of the past in a particular way via the medium of television,

  20. Milieucondities van aquatische beheertypen

    NARCIS (Netherlands)

    Loeb, R.; Verdonschot, P.F.M.

    2010-01-01

    Voor de beheertypen van Index-NL is invulling gegeven aan de kwaliteitsaspecten van de aquatische typen. De kwaliteit in de Index-NL typen wordt afgemeten aan de (1) biotische natuur, (2) milieucondities, (3) ruimtelijke samenhang, (4) structuur en beheer, en (5) natuurlijke processen. In deze

  1. Photodynamic therapy of necrobiosis lipoidica--a multicenter study of 18 patients

    DEFF Research Database (Denmark)

    Berking, C; Hegyi, J; Arenberger, P

    2008-01-01

    BACKGROUND: Necrobiosis lipoidica (NL) is a granulomatous skin disease of unknown origin, and no reliably effective treatment option exists to handle this often disfiguring disease. Recently, a patient with long-lasting NL was reported to be cured by topical photodynamic therapy (PDT). OBJECTIVE...

  2. 76 FR 50269 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance and...

    Science.gov (United States)

    2011-08-12

    ...' industry (i.e., conditions within the industry are adverse). Affirmative Determinations for Worker... the Trade Act have been met. TA-W-80,032; NL Fashion, Inc., New York, New York: February 27, 2010. TA... firm does not have a significant number of workers 50 years of age or older. TA-W-80,032; NL Fashion...

  3. Association of the cad-n1 allele with increased stem growth and wood density in full-sib families of loblolly pine

    Science.gov (United States)

    Q. Yu; B. Li; C.D. Nelson; S.E. McKeand; T.J. Mullin

    2005-01-01

    Stem growth and wood density associated with a mutant null (cad-nl) allele were examined in three 15-year old loblolly pine half-diallel tests established on two sites in the southern United States. In each half-diallel test, one or two cad-nl heterozygous parents were crossed with five unrelated wild-type parents to produce five...

  4. The Netherlands Bird Avoidance Model, Final Report

    NARCIS (Netherlands)

    Shamoun-Baranes, J.; Bouten, W.; Sierdsema, H.; van Belle, J.; van Gasteren, J.R.; van Loon, E.E.

    2006-01-01

    The NL-BAM was developed as a web-based decision support tool to be used by the bird hazard avoidance experts in the ecology unit of the Royal Netherlands Air Force. The NL-BAM will be used together with the ROBIN 4 radar system to provide BirdTAMS, for real time warnings and flight planning and to

  5. Potential energy surfaces for Ж = , Ne- Ba nuclei

    Indian Academy of Sciences (India)

    112Ba nu- clei in an axially deformed relativistic mean field approach. A quadratic constraint scheme is applied to determine the complete energy surface for a wide range of the quadrupole deformation. The NL3, NL-RA1 and TM1 parameter sets ...

  6. Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy

    NARCIS (Netherlands)

    Walls, Alexandra C; Tortorici, M Alejandra; Frenz, Brandon; Snijder, Joost|info:eu-repo/dai/nl/338018328; Li, Wentao|info:eu-repo/dai/nl/411296272; Rey, Félix A; DiMaio, Frank; Bosch, Berend-Jan|info:eu-repo/dai/nl/273306049; Veesler, David

    2016-01-01

    The threat of a major coronavirus pandemic urges the development of strategies to combat these pathogens. Human coronavirus NL63 (HCoV-NL63) is an α-coronavirus that can cause severe lower-respiratory-tract infections requiring hospitalization. We report here the 3.4-Å-resolution cryo-EM

  7. Detecting Target Objects by Natural Language Instructions Using an RGB-D Camera

    Directory of Open Access Journals (Sweden)

    Jiatong Bao

    2016-12-01

    Full Text Available Controlling robots by natural language (NL is increasingly attracting attention for its versatility, convenience and no need of extensive training for users. Grounding is a crucial challenge of this problem to enable robots to understand NL instructions from humans. This paper mainly explores the object grounding problem and concretely studies how to detect target objects by the NL instructions using an RGB-D camera in robotic manipulation applications. In particular, a simple yet robust vision algorithm is applied to segment objects of interest. With the metric information of all segmented objects, the object attributes and relations between objects are further extracted. The NL instructions that incorporate multiple cues for object specifications are parsed into domain-specific annotations. The annotations from NL and extracted information from the RGB-D camera are matched in a computational state estimation framework to search all possible object grounding states. The final grounding is accomplished by selecting the states which have the maximum probabilities. An RGB-D scene dataset associated with different groups of NL instructions based on different cognition levels of the robot are collected. Quantitative evaluations on the dataset illustrate the advantages of the proposed method. The experiments of NL controlled object manipulation and NL-based task programming using a mobile manipulator show its effectiveness and practicability in robotic applications.

  8. Google je wijs!

    NARCIS (Netherlands)

    Brand-Gruwel, Saskia; Koper, Rob; Kalz, Marco; Van Meeuwen, Ludo; Berkhout, Jeroen; Storm, Jeroen; Wolff, Charlotte

    2011-01-01

    Brand-Gruwel, S., Koper, R., Kalz, M., Van Meeuwen, L., Berkhout, J., Storm, J., & Wolf, C. (2011, december). Google je wijs! Masterclass in de OpenU community. Open universiteit, Heerlen, Nederland. Beschikbaar op http://portal.ou.nl/nl/web/masterclass-google-je-wijs/introductie

  9. SAJCH 613.indd

    African Journals Online (AJOL)

    Am J Clin Pathol 2011;136(2):183-194. [http://dx.doi.org/10.1309/. AJCPV1I2QWKZKNJH]. 2. Stein H, Harris NL, Campo E. Plasmablastic lymphoma. In: Swerdlow SH,. Campo E, Harris NL, et al., eds. World Health Organization Classification of. Tumours of Haematopoietic and Lymphoid Tissues. 4th ed. Lyon, France: IARC.

  10. Identification of compounds from the plant species Alepidea amatymbica active against HIV

    CSIR Research Space (South Africa)

    Louvel, S

    2013-05-01

    Full Text Available extraction–purification approach; extracts and therein sub-fractions of A. amatymbica were assessed in a cell-based assay targeting the replication of prototypic CXCR4-tropic (NL4-3) or CCR5-tropic (NL-AD87) HIV-1 strains. Sub-fractions of the extracts were...

  11. Axonal cleaved caspase-3 regulates axon targeting and morphogenesis in the developing auditory brainstem

    Directory of Open Access Journals (Sweden)

    Sarah E Rotschafer

    2016-10-01

    Full Text Available Caspase-3 is a cysteine protease that is most commonly associated with cell death. Recent studies have shown additional roles in mediating cell differentiation, cell proliferation, and development of cell morphology. We investigated the role of caspase-3 in the development of chick auditory brainstem nuclei during embryogenesis. Immunofluorescence from embryonic days E6-13 revealed that the temporal expression of cleaved caspase-3 follows the ascending anatomical pathway. Expression is first seen in the auditory portion of VIIIth nerve including central axonal regions projecting to nucleus magnocellularis (NM, then later in NM axons projecting to nucleus laminaris (NL, and subsequently in NL dendrites. To examine the function of cleaved caspase-3 in chick auditory brainstem development, we blocked caspase-3 cleavage in developing chick embryos with the caspase-3 inhibitor Z-DEVD-FMK from E6 to E9, then examined NM and NL morphology and NM axonal targeting on E10. NL lamination in treated embryos was disorganized and the neuropil around NL contained a significant number of glial cells normally excluded from this region. Additionally, NM axons projected into inappropriate portions of NL in Z-DEVD-FMK treated embyros. We found that the presence of misrouted axons was associated with more severe NL disorganization. The effects of axonal caspase-3 inhibition on both NL morphogenesis and NM axon targeting suggest that these developmental processes are coordinated, likely through communication between axons and their targets.

  12. Psychometric Properties of the Five Facets Mindfulness Questionnaire (FFMQ) in a Meditating and a Non-Meditating Sample

    Science.gov (United States)

    de Bruin, Esther I.; Topper, Maurice; Muskens, Jan G. A. M.; Bogels, Susan M.; Kamphuis, Jan H.

    2012-01-01

    The factor structure, internal consistency, construct validity, and predictive validity of the Dutch version of the Five Facet Mindfulness Questionnaire (FFMQ-NL) were studied in a sample of meditators (n = 288) and nonmeditators (n = 451). A five-factor structure was demonstrated in both samples, and the FFMQ-NL and its subscales were shown to…

  13. Neurolymphomatosis: An International Primary CNS Lymphoma Collaborative Group report

    NARCIS (Netherlands)

    S. Grisariu (Sigal); B. Avni (Batia); T.T. Batchelor (Tracy); M.J. van den Bent (Martin); F. Bokstein (Felix); D. Schiff (David); O. Kuittinen (Outi); M.C. Chamberlain (Marc C.); P. Roth (Patrick); A. Nemets (Anatoly); E. Shalom (Edna); D. Ben-Yehuda (Dina); T. Siegal (Tali)

    2010-01-01

    textabstractNeurolymphomatosis (NL) is a rare clinical entity. The International Primary CNS Lymphoma Collaborative Group retrospectively analyzed 50 patients assembled from 12 centers in 5 countries over a 16-year period. NL was related to non-Hodgkin lymphoma in 90% and to acute leukemia in 10%.

  14. The Effect of Visual Variability on the Learning of Academic Concepts

    Science.gov (United States)

    Bourgoyne, Ashley; Alt, Mary

    2017-01-01

    Purpose: The purpose of this study was to identify effects of variability of visual input on development of conceptual representations of academic concepts for college-age students with normal language (NL) and those with language-learning disabilities (LLD). Method: Students with NL (n = 11) and LLD (n = 11) participated in a computer-based…

  15. Dykes of standards supporting polders of data : The practices used in the Netherlands for making archaeological data available and accessible

    NARCIS (Netherlands)

    Gilissen, V.

    2014-01-01

    In the Netherlands, the archiving and publication of archaeological research data has led to the establishment of EDNA, the e-Depot for Dutch Archaeology http://www.edna.nl/, accommodated at DANS (Data Archiving and Networked Services) http://dans.knaw.nl/en. EDNA is a collaboration between DANS and

  16. Validity of Self-Reported Pedometer Steps per Day in College Students

    Science.gov (United States)

    Overstreet, Brittany Star; Crouter, Scott E.; Butler, George A.; Springer, Cary M.; Bassett, David R.

    2016-01-01

    The purpose of this article was to examine the validity of self-reported pedometer steps/day. Forty-seven participants were provided a New Lifestyles NL-2000 (NL-2000; Lees Summit, MO, USA) pedometer and a physical activity (PA) diary for 3 weeks, but not informed of the data-storing capabilities. For weeks 2 and 3, each participant was given a…

  17. Measurement of speech parameters in casual speech of dementia patients

    NARCIS (Netherlands)

    Ossewaarde, Roelant; Jonkers, Roel; Jalvingh, Fedor; Bastiaanse, Yvonne

    Measurement of speech parameters in casual speech of dementia patients Roelant Adriaan Ossewaarde1,2, Roel Jonkers1, Fedor Jalvingh1,3, Roelien Bastiaanse1 1CLCG, University of Groningen (NL); 2HU University of Applied Sciences Utrecht (NL); 33St. Marienhospital - Vechta, Geriatric Clinic Vechta

  18. Characterization and cloning of TMV resistance gene N homologues ...

    African Journals Online (AJOL)

    Tobacco cultivars Nicotiana tabacum cv. Samsun NN plants carrying the N gene contain a multitude of N-related genes. We cloned a few N homologues and isolated two full-length cDNAs of NL-C26 and NL-B69 genes from N. tabacum cv. Samsun NN. Nucleotide sequence analysis showed that the coding regions of ...

  19. Access to Grey Literature in the Netherlands : Grey Literature at Data Archiving and Networked Services – DANS

    NARCIS (Netherlands)

    Dijk, E.M.S.; Doorn, P.K.

    Data Archiving and Networked Services (DANS) is the national Dutch organization for permanent access to research data, with a focus on the humanities and social sciences. DANS offers three services to the scholarly community: DataverseNL, EASY, and NARCIS. DataverseNL is intended to support data

  20. Estimates of genetic parameters and genetic trend for fur traits in a ...

    African Journals Online (AJOL)

    Ph.D.-tesis, Universiteit van. Stellenbosch. VAN NlEKERK, AJ.A., 1972. 'n Studie van teeltprobleme by. Karakoelskape met spesiale verwysing na die Niemollerkudde. D.Sc.(Agric)-tesis, Universiteit van die 0. V.S., Bloemfontein. VAN NlEKERK, AJ.A., SCHOEMAN, SJ. & NEL, J.A., 1968. Oorerflikhede van en genetiese ...

  1. Random noise suppression of seismic data using non-local Bayes algorithm

    Science.gov (United States)

    Chang, De-Kuan; Yang, Wu-Yang; Wang, Yi-Hui; Yang, Qing; Wei, Xin-Jian; Feng, Xiao-Ying

    2018-02-01

    For random noise suppression of seismic data, we present a non-local Bayes (NL-Bayes) filtering algorithm. The NL-Bayes algorithm uses the Gaussian model instead of the weighted average of all similar patches in the NL-means algorithm to reduce the fuzzy of structural details, thereby improving the denoising performance. In the denoising process of seismic data, the size and the number of patches in the Gaussian model are adaptively calculated according to the standard deviation of noise. The NL-Bayes algorithm requires two iterations to complete seismic data denoising, but the second iteration makes use of denoised seismic data from the first iteration to calculate the better mean and covariance of the patch Gaussian model for improving the similarity of patches and achieving the purpose of denoising. Tests with synthetic and real data sets demonstrate that the NL-Bayes algorithm can effectively improve the SNR and preserve the fidelity of seismic data.

  2. The many faces of necrobiosis lipoidica: a report of three cases with histologic variations

    Directory of Open Access Journals (Sweden)

    Pei-Shan Yen

    2011-06-01

    Full Text Available Necrobiosis lipoidica (NL is a granulomatous disease with unknown etiology and pathogenesis. Clinically, it is characterized by yellow-brown atrophic plaques with inflammatory rims on shins. Histologically, it shows diffused palisade and interstitial granulomatous dermatitis with focal connective tissue degeneration (necrobiosis. We described three non-diabetic NL cases with unusual histologic features. All patients presented erythematous to brownish plaque(s on the shin(s. In Case 1, in addition to the characteristics of NL, the biopsy showed dense perineural infiltration, which may explain the pathogenesis of the anesthesia of NL lesions. In Case 2, well-formed tuberculoid granulomas were of special interest. In Case 3, there was conspicuous lobular panniculitis. These histologic features present difficulties in the diagnosis and represent the broad spectrum of NL lesions, histologically.

  3. Constraints on Primordial Non-Gaussianity from 800 000 Photometric Quasars.

    Science.gov (United States)

    Leistedt, Boris; Peiris, Hiranya V; Roth, Nina

    2014-11-28

    We derive robust constraints on primordial non-Gaussianity (PNG) using the clustering of 800 000 photometric quasars from the Sloan Digital Sky Survey in the redshift range 0.5constraints lead to -105running parameter n_{f_{NL}} to constrain b(k)∝k^{-2+n_{f_{NL}}} and a generalized PNG amplitude f[over ˜]_{NL}, we obtain -45.5 exp(3.7n_{f_{NL}})constraints obtained to date on PNG using a single population of large-scale structure tracers, and are already at the level of pre-Planck constraints from the cosmic microwave background. A conservative forecast for a Large Synoptic Survey Telescope (LSST)-like survey incorporating mode projection yields σ(f_{NL})∼5-competitive with the Planck result-highlighting the power of upcoming large scale structure surveys to probe the initial conditions of the Universe.

  4. Is nephrolithiasis an unrecognized extra-articular manifestation in ankylosing spondylitis?

    DEFF Research Database (Denmark)

    Jakobsen, Ane Krag; Jacobsson, Lennart T H; Patschan, Oliver

    2014-01-01

    of NL in Swedish patients with AS compared to the general population. METHODS AND FINDINGS: We performed a prospective population-based nationwide cohort study based on linkage of data from Swedish registries. 8,572 AS patients were followed for 49,258 person-years (py) and 39,639 matched general...... for comorbidities and treatment, and to assess predictors for NL. Mean age at study entry was 46 years (inter quartile range 36-56 years), 65% were males. Based on 250 vs. 466 NL events, the adjusted HR of NL in AS patients was 2.1 (95%CI 1.8 to 2.4). Predictors of NL within the AS group included prior diagnosis...

  5. Neurolymphomatosis of Brachial Plexus in Patients with Non-Hodgkin's Lymphoma

    Directory of Open Access Journals (Sweden)

    Yong Jun Choi

    2013-01-01

    Full Text Available Neurolymphomatosis (NL is a rare clinical disease where neoplastic cells invade the cranial nerves and peripheral nerve roots, plexus, or other nerves in patients with hematologic malignancy. Most NL cases are caused by B-cell non-Hodgkin’s lymphoma (NHL. Diagnosis can be made by imaging with positron emission tomography (PET and magnetic resonance imaging (MRI. We experienced two cases of NL involving the brachial plexus in patients with NHL. One patient, who had NHL with central nervous system (CNS involvement, experienced complete remission after 8 cycles of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy but relapsed into NL of the brachial plexus 5 months later. The other patient, who suffered from primary central nervous system lymphoma (PCNSL, had been undergoing chemoradiotherapy but progressed to NL of the brachial plexus.

  6. Characterization of heat shock protein 70 transcript from Nilaparvata lugens (Stål): Its response to temperature and insecticide stresses.

    Science.gov (United States)

    Lu, Kai; Chen, Xia; Liu, Wenting; Zhang, Zhichao; Wang, Ying; You, Keke; Li, Yue; Zhang, Rongbin; Zhou, Qiang

    2017-10-01

    The brown planthopper, Nilaparvata lugens, possesses a strong adaptability to extreme temperature and insecticide stresses. Heat shock proteins (Hsps) are highly conserved molecular chaperones and play a pivotal role in response to various environmental stresses in insects. However, little is known about the response of Hsps to stresses in N. lugens. In the present study, an inducible Hsp70 (NlHsp70) was isolated from this insect and transcriptional expression patterns of NlHsp70 under temperature and insecticide stresses were analyzed. The full-length of NlHsp70 was 2805bp with an open reading frame (ORF) of 1896bp, showing high homology to its counterparts in other species. Expression of NlHsp70 was not altered by heat shock for 1h, nor following recovery from thermal stress. Conversely, decreased expression of NlHsp70 was observed in response to cold shock. In addition, the expression of NlHsp70 increased after imidacloprid exposure. RNA interference experiment combined with insecticide injury assay also demonstrated that NlHsp70 was essential for resistance against insecticide exposure. These observations indicated that NlHsp70 was an important gene involved in the resistance or tolerance to environmental stresses in N. lugens. Interestingly, weak changes in mRNA expression levels of two thermal-inducible Hsp genes, NlHsp90 and NlHsc70 were observed in imidacloprid-exposed N. lugens adults, suggesting that different Hsps may respond differential to the extreme temperature and insecticide stresses. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Probing Inflation Using Galaxy Clustering On Ultra-Large Scales

    Science.gov (United States)

    Dalal, Roohi; de Putter, Roland; Dore, Olivier

    2018-01-01

    A detailed understanding of curvature perturbations in the universe is necessary to constrain theories of inflation. In particular, measurements of the local non-gaussianity parameter, flocNL, enable us to distinguish between two broad classes of inflationary theories, single-field and multi-field inflation. While most single-field theories predict flocNL ≈ ‑5/12 (ns -1), in multi-field theories, flocNL is not constrained to this value and is allowed to be observably large. Achieving σ(flocNL) = 1 would give us discovery potential for detecting multi-field inflation, while finding flocNL=0 would rule out a good fraction of interesting multi-field models. We study the use of galaxy clustering on ultra-large scales to achieve this level of constraint on flocNL. Upcoming surveys such as Euclid and LSST will give us galaxy catalogs from which we can construct the galaxy power spectrum and hence infer a value of flocNL. We consider two possible methods of determining the galaxy power spectrum from a catalog of galaxy positions: the traditional Feldman Kaiser Peacock (FKP) Power Spectrum Estimator, and an Optimal Quadratic Estimator (OQE). We implemented and tested each method using mock galaxy catalogs, and compared the resulting constraints on flocNL. We find that the FKP estimator can measure flocNL in an unbiased way, but there remains room for improvement in its precision. We also find that the OQE is not computationally fast, but remains a promising option due to its ability to isolate the power spectrum at large scales. We plan to extend this research to study alternative methods, such as pixel-based likelihood functions. We also plan to study the impact of general relativistic effects at these scales on our ability to measure flocNL.

  8. Effects of GaN/AlGaN/Sputtered AlN nucleation layers on performance of GaN-based ultraviolet light-emitting diodes

    Science.gov (United States)

    Hu, Hongpo; Zhou, Shengjun; Liu, Xingtong; Gao, Yilin; Gui, Chengqun; Liu, Sheng

    2017-03-01

    We report on the demonstration of GaN-based ultraviolet light-emitting diodes (UV LEDs) emitting at 375 nm grown on patterned sapphire substrate (PSS) with in-situ low temperature GaN/AlGaN nucleation layers (NLs) and ex-situ sputtered AlN NL. The threading dislocation (TD) densities in GaN-based UV LEDs with GaN/AlGaN/sputtered AlN NLs were determined by high-resolution X-ray diffraction (XRD) and cross-sectional transmission electron microscopy (TEM), which revealed that the TD density in UV LED with AlGaN NL was the highest, whereas that in UV LED with sputtered AlN NL was the lowest. The light output power (LOP) of UV LED with AlGaN NL was 18.2% higher than that of UV LED with GaN NL owing to a decrease in the absorption of 375 nm UV light in the AlGaN NL with a larger bandgap. Using a sputtered AlN NL instead of the AlGaN NL, the LOP of UV LED was further enhanced by 11.3%, which is attributed to reduced TD density in InGaN/AlInGaN active region. In the sputtered AlN thickness range of 10-25 nm, the LOP of UV LED with 15-nm-thick sputtered AlN NL was the highest, revealing that optimum thickness of the sputtered AlN NL is around 15 nm.

  9. スマートフォンによる青少年のインターネット依存および親子関係と依存の関連(II-2 メディア・情報行動2(青少年),セッションII,自由論題報告)

    OpenAIRE

    堀川, 裕介; 橋元, 良明; 千葉, 直子; 関, 良明; 原田, 悠輔; Yusuke, HORIKAWA; Yoshiaki, HASHIMOTO; Naoko, CHIBA; Yoshiaki, SEKI; Yusuke, HARATA; 東京大学大学院学際情報学府; 東京大学大学院情報学環; NTTセキュアプラットフォーム研究所; NTTセキュアプラットフォーム研究所; 東京大学大学院学際情報学府

    2013-01-01

    Abstract With the spread of Smartphone, the present conditions of the Internet Addiction Disorder (IAD) among adolescents attract social attention. Using the child-parent questionnaire survey investigated by our group in 2012, we analyzed the relations between the IAD and 1)Smartphone usage and 2)child-parent relationship. Consequently, conflict of child-parent relationship is the important related factor of the IAD.

  10. Dimetal Complexes of a Bibrachial 2+2 Thiolate-based Macrocycle

    DEFF Research Database (Denmark)

    Lennartson, Anders; McKee, Vickie; Nelson, Jane

    2012-01-01

    Protocols for accessing the [2+3] and [2+2] tren + thiophenolate-based cryptands and macrocycles, respectively, have been devised; however, a propensity towards incomplete crypt formation is clear: Cd(II)2, Mn(II)2, Ni(II)2 and Pd(II)2 complexes of the [2+2] bibrachial systems in which one arm of...

  11. Status Review of Wildlife Mitigation, Columbia Basin Hydroelectric Projects, Washington Facilities (Intrastate) Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    Howerton, Jack

    1984-11-01

    This report was prepared for BPA in fulfillment of section 1004 (b)(1) of the Pacific Northwest Electric Power Planning and Conservation Act of 1980, to review the status of past, present, and proposed future wildlife planning and mitigation program at existing hydroelectric projects in the Columbia River Basin. The project evaluations will form the basis for determining any needed remedial measures or additional project analysis. Projects addressed are: Merwin Dam; Swift Project; Yale Project; Cowlitz River; Boundary Dam; Box Canyon Dam; Lake Chelan; Condit Project; Enloe Project; Spokane River; Tumwater and Dryden Dam; Yakima; and Naches Project.

  12. Guidelines and Data to Support Plans for Reallocating Food during Crisis Relocation. Regional Appendix. FEMA Region X,

    Science.gov (United States)

    1982-09-01

    HOUSES ($1000) SERVED STORE 1 SAFEWAY STORES 4 1,572,750 275 5,719 SAFE14AY STORES INC BELLEVUE WA 725,000 119 6,092 CLACKAMAS OR 504,500 94 5,367...These three distributors, Safeway Stores, West Coast Grocery, and U R M Stores, supply over 96% of the food consumed in the Spokane risk area, and...distributors, U R M Stores supplies over 40% of the Conglomerate’s retail food stores, while West Coast Grocery and Safeway Stores command 31% and Z2% of

  13. Columbia River system operation review: Final environmental impact statement. Main report exhibits

    International Nuclear Information System (INIS)

    1995-11-01

    This Volume is a part of the Final Environmental Impact Statement (EIS) for the Columbia River System. This volume contains technical exhibits of cultural resources and commentary on the (System Operation Review) SOR process. The Confederated Tribes of the Umatilla Indian Reservation comment is the majority of the material in the volume, in the Consultation Plan, Identification of trust resources; Criteria for the selection of a System Operating Strategy; comment on rights protection and implementation of Federal Trust responsibility; analysis of the draft EIS. Comment by other Native American Tribes and groups is also included: Confederated Tribes of the Colville Reservation; Kootenai Tribe of Idaho; Spokane Tribe of Indians; Coeur d' Alene tribe

  14. Columbia River System Operation Review : Final Environmental Impact Statement, Main Report Exhibits.

    Energy Technology Data Exchange (ETDEWEB)

    Columbia River System Operation Review (U.S.)

    1995-11-01

    This Volume is a part of the Final Environmental Impact Statement (EIS) for the Columbia River System. This volume contains technical exhibits of cultural resources and commentary on the (System Operation Review) SOR process. The Confederated Tribes of the Umatilla Indian Reservation comment is the majority of the material in the volume, in the Consultation Plan, Identification of trust resources; Criteria for the selection of a System Operating Strategy; comment on rights protection and implementation of Federal Trust responsibility; analysis of the draft EIS. Comment by other Native American Tribes and groups is also included: Confederated Tribes of the Colville Reservation; Kootenai Tribe of Idaho; Spokane Tribe of Indians; Coeur d` Alene tribe.

  15. Removal of methyl violet 2B dye from aqueous solution using Nepenthes rafflesiana pitcher and leaves

    Science.gov (United States)

    Kooh, Muhammad Raziq Rahimi; Dahri, Muhammad Khairud; Lim, Linda B. L.

    2017-11-01

    This study reported Nepenthes rafflesiana pitcher (NP) and Nepenthes rafflesiana leaves (NL) as new adsorbents for methyl violet (MV) dye. The experiments were done using 2 h contact time and without any pH alteration (pH 4.4). The effects of pH and ionic strength revealed hydrophobic-hydrophobic interaction as the predominant force of dye interaction with the adsorbent. Both NP-MV and NL-MV followed pseudo-second-order model indicating the adsorption processes may be governed by chemical process. Weber-Morris intraparticle diffusion model verified that the rate-limiting step of both the NP-MV and NL-MV systems is not intraparticle diffusion. The Langmuir model best described the adsorption process with high maximum monolayer adsorption ( q m) of 288.7 and 194.0 mg g-1 for NP-MV and NL-MV, respectively. Thermodynamics studies revealed both NP-MV and NL-MV systems are spontaneous and endothermic in nature. From the regeneration study, it was found that NP's and NL's adsorption capacities could be recovered using distilled water and base whereby distilled water was able to recover 78% (NP) and 71% (NL) while base was able to recover 82% for both samples after three regeneration cycles.

  16. HUMIFIED FRACTION OF ORGANIC MATTER DUE TO PLANT MIXTURE CULTIVATION

    Directory of Open Access Journals (Sweden)

    TONY JARBAS FERREIRA CUNHA

    2016-01-01

    Full Text Available The aim of this study was to assess the organic matter changes in quantity and quality, particularly of the humic fraction in the surface layer (0–20 cm, of a Typic Plinthustalf soil under different management of plant mixtures used as green manure for mango (Mangifera indica L. crops. The plant mixtures, which were seeded between rows of mango trees, were formed by two groups of leguminous and non-leguminous plants. Prior to sowing, seeds were combined in different proportions and compositions constituting the following treatments: 100% non-leguminous species (NL; 100% leguminous species (L; 75% L and 25% NL; 50% L and 50% NL; 25% L and 75% NL; and 100% spontaneous vegetation, considered a control. The plant mixtures that grew between rows of mango trees caused changes in the chemical composition of the soil organic matter, especially for the treatments 50% L and 50% NL and 25% L and 75% NL, which increased the content of humic substances in the soil organic matter. However, the treatment 25% L and 75% NL was best at minimising loss of total organic carbon from the soil. The humic acids studied have mostly aliphatic characteristics, showing large amounts of carboxylic and nitrogen groups and indicating that most of the organic carbon was formed by humic substances, with fulvic acid dominating among the alkali soluble fractions.

  17. NBD-based fluorescent chemosensor for the selective quantification of copper and sulfide in an aqueous solution and living cells.

    Science.gov (United States)

    Meng, Qingtao; Shi, Yu; Wang, Cuiping; Jia, Hongmin; Gao, Xue; Zhang, Run; Wang, Yongfei; Zhang, Zhiqiang

    2015-03-14

    Chemosensors play important roles in cation and anion recognition in biological, industrial, and environmental processes. Although many efforts have been made to develop artificial fluorescent receptors for Cu(2+) and S(2-), their applications in the detection in bulk solutions are limited. In this work, we report a novel fluorescence chemosensor (NL) based on the 7-nitrobenz-2-oxa-1,3-diazole (NBD) fluorophore for the quantification of Cu(2+) and S(2-) in single intact cells. NL specifically binds to Cu(2+) in the presence of other competing cations, and evident changes in UV-vis and fluorescence spectra in HEPES buffer are noticed. Based on the displacement approach, the selective sense S(2-) with the in situ generated NL-Cu(2+) ensemble gives a remarkable recovery of fluorescence and UV-vis absorption spectra. The detection limits of NL for Cu(2+) and NL-Cu(2+) for S(2-) were estimated to be 1.6 nM and 0.17 μM, respectively. NL and the resultant complex NL-Cu(2+) exhibit low cytotoxicity and cell-membrane permeability, which makes them capable of Cu(2+) and S(2-) imaging and quantification in living MDA-MB-231 cells.

  18. Necrobiosis lipoidica: a descriptive study of 35 cases.

    Science.gov (United States)

    Marcoval, J; Gómez-Armayones, S; Valentí-Medina, F; Bonfill-Ortí, M; Martínez-Molina, L

    2015-06-01

    Necrobiosis lipoidica (NL) is a chronic idiopathic granulomatous disease considered to occur in association with diabetes mellitus. Data on the frequency of this association, however, are inconsistent. Our aim was to retrospectively analyze the clinical characteristics of patients diagnosed with NL at our hospital and to investigate the association with diabetes mellitus and other diseases. We performed a chart review of all patients with a clinical and histologic diagnosis of NL treated and followed in the dermatology department of Hospital de Bellvitge in Barcelona, Spain between 1987 and 2013. Thirty-five patients (6 men and 29 women with a mean age of 47.20 years) were diagnosed with NL in the study period. At the time of diagnosis, 31 patients had pretibial lesions. Thirteen patients (37%) had a single lesion at diagnosis, and the mean number of lesions was 3.37. Twenty-three patients (65.71%) had diabetes mellitus (type 1 in 10 cases and type 2 in 13). In 20 patients, onset of diabetes preceded that of NL by a mean of 135.70 months. The 2 conditions were diagnosed simultaneously in 3 patients. None of the 35 patients developed diabetes mellitus during follow-up. Six patients had hypothyroidism, and 4 of these also had type 1 diabetes. NL is frequently associated with type 1 and 2 diabetes. Although diabetes tends to develop before NL, it can occur simultaneously. Copyright © 2014 Elsevier España, S.L.U. and AEDV. All rights reserved.

  19. SOX10-Nano-Lantern Reporter Human iPS Cells; A Versatile Tool for Neural Crest Research.

    Directory of Open Access Journals (Sweden)

    Tomoko Horikiri

    Full Text Available The neural crest is a source to produce multipotent neural crest stem cells that have a potential to differentiate into diverse cell types. The transcription factor SOX10 is expressed through early neural crest progenitors and stem cells in vertebrates. Here we report the generation of SOX10-Nano-lantern (NL reporter human induced pluripotent stem cells (hiPS by using CRISPR/Cas9 systems, that are beneficial to investigate the generation and maintenance of neural crest progenitor cells. SOX10-NL positive cells are produced transiently from hiPS cells by treatment with TGFβ inhibitor SB431542 and GSK3 inhibitor CHIR99021. We found that all SOX10-NL-positive cells expressed an early neural crest marker NGFR, however SOX10-NL-positive cells purified from differentiated hiPS cells progressively attenuate their NL-expression under proliferation. We therefore attempted to maintain SOX10-NL-positive cells with additional signaling on the plane and sphere culture conditions. These SOX10-NL cells provide us to investigate mass culture with neural crest cells for stem cell research.

  20. Estimators for local non-Gaussianities

    International Nuclear Information System (INIS)

    Creminelli, P.; Senatore, L.; Zaldarriaga, M.

    2006-05-01

    We study the Likelihood function of data given f NL for the so-called local type of non-Gaussianity. In this case the curvature perturbation is a non-linear function, local in real space, of a Gaussian random field. We compute the Cramer-Rao bound for f NL and show that for small values of f NL the 3- point function estimator saturates the bound and is equivalent to calculating the full Likelihood of the data. However, for sufficiently large f NL , the naive 3-point function estimator has a much larger variance than previously thought. In the limit in which the departure from Gaussianity is detected with high confidence, error bars on f NL only decrease as 1/ln N pix rather than N pix -1/2 as the size of the data set increases. We identify the physical origin of this behavior and explain why it only affects the local type of non- Gaussianity, where the contribution of the first multipoles is always relevant. We find a simple improvement to the 3-point function estimator that makes the square root of its variance decrease as N pix -1/2 even for large f NL , asymptotically approaching the Cramer-Rao bound. We show that using the modified estimator is practically equivalent to computing the full Likelihood of f NL given the data. Thus other statistics of the data, such as the 4-point function and Minkowski functionals, contain no additional information on f NL . In particular, we explicitly show that the recent claims about the relevance of the 4-point function are not correct. By direct inspection of the Likelihood, we show that the data do not contain enough information for any statistic to be able to constrain higher order terms in the relation between the Gaussian field and the curvature perturbation, unless these are orders of magnitude larger than the size suggested by the current limits on f NL . (author)

  1. Evolution of neuroleptic-induced extrapyramidal syndromes under long-term neuroleptic treatment.

    Science.gov (United States)

    Modestin, Jiri; Wehrli, Marianne Vogt; Stephan, Patrik Lukas; Agarwalla, Puspa

    2008-03-01

    The long-term evolution of neuroleptic-induced extrapyramidal syndromes (EPS) of Parkinsonism, akathisia and tardive dyskinesia (TD) is still a controversial issue worth exploring. A total of 200 inpatients on regular typical neuroleptics (NL) and/or clozapine were assessed in 1995 with regard to the prevalence of EPS. Altogether, 83 patients could be reassessed in 2003/04 (63 had died) using the same methods. Strict definitions of EPS were used. The complete account of NL therapy the patients were prescribed between 1995 and 2003/04 (including atypical NL other than clozapine) was considered. The prevalences found in 1995 and 2003/04 were 17% and 29% for Parkinsonism, 14% and 14% for akathisia, and 24% and 13% for TD. There were considerable intra-individual fluctuations in EPS occurrence even when the overall prevalence rate remained the same. In intra-individual comparisons of EPS ratings on both assessments, there was a tendency for worsening of Parkinsonism to be associated with a current (2003/04) therapy with typical NL; worsening of akathisia was associated with a current therapy with atypical NL other than clozapine, amelioration of akathisia with a current therapy with clozapine; and, basically, there were no significant associations found between the changes in TD ratings and the long-term therapy with typical NL, clozapine, and other atypical NL, considering cumulative doses of all these drugs. In a multivariate analysis, there was a tendency for the long-term evolution of TD to depend on illness duration as the only variable. There are intra-individual fluctuations in all EPS over longer time periods. The choice of current NL therapy has an impact on Parkinsonism and akathisia. The long-term evolution of TD appears independent of NL prescriptions.

  2. General Aviation Activity and Avionics Survey 1986.

    Science.gov (United States)

    1987-12-01

    personal, instructional, research, patrol, and sport flying. General aviation aircraft range in complexity from simple gliders and balloons to four engine...N In N N N ML nm D I N C’) Inncc. 0A 0n w 4 4 NL t---I IN N Z0m l tC) L nL n vmr n 0 nL 4. -n 0 1W M’C) 0I ’) - ’) - In-- - - Ŕa) C’In N In ’IT N I...3802051 SCWZERSGI 8050122 SKRSKYS64 8142604 SPORT GEOPEN 3802433 SCWZERSG1 8050124 SKRSKYS70 8143000 SPTPUZRF40 8451012 SCWZERSG1 8050146 SKRSKYS76

  3. Dutch Nature and Environmental Compendium 2003

    International Nuclear Information System (INIS)

    2003-01-01

    The title publication comprises all the data on the nature and the environment in the Netherlands, information on related policy, references to data sources and recent research. The data and the information on the website are published in print, but the most actual data can be found on the site. The first book with the title Nature Compendium was published in April 2003. The second edition of the Environmental Compendium was published as a book in October 2001. Since March 2003 the websites of the Environmental Compendium and the Nature Compendium are integrated in one site: www.rivm.nl/milieuennatuurcompendium/nl/ [nl

  4. Avaliação de características de crescimento pós-desmama de animais Nelore puros e cruzados no estado do Mato Grosso do Sul Post-weaning traits evaluation of straightbred and crossbred Nellore cattle in Mato Grosso do Sul state

    Directory of Open Access Journals (Sweden)

    Carolina Amália de Souza Dantas Muniz

    1999-08-01

    Full Text Available Com o objetivo de comparar o desempenho de diferentes grupos genéticos para características de crescimento, foram usadas 2888 observações de peso ajustado aos 365 dias (P365 e de ganho médio diário da desmama aos 365 dias (G365 e 1909 observações de peso ajustado aos 550 dias de idade (P550 e de ganho médio diário dos 365 aos 550 dias de idade (G550 de animais F1, oriundos do cruzamento de vacas Nelore com touros Aberdeen Angus, Brangus (pelagens preta e vermelha, Canchim, Gelbvieh, Nelore e Simental, no Estado Mato Grosso do Sul. Os grupos genéticos F1 estudados foram os seguintes: 1/2 Aberdeen Angus + 1/2 Nelore (1AG1NL, 1/2 Brangus (pelagem preta + 1/2 Nelore (1BA1NL, 1/2 Brangus (pelagem vermelha + 1/2 Nelore (1BV1NL, 1/2 Canchim + 1/2 Nelore (1CN1NL, 1/2 Gelbvieh + 1/2 Nelore (1GL1NL, 1/2 Simental + 1/2 Nelore (1SM1NL e Nelore. As análises estatísticas foram feitas pelo método dos quadrados mínimos e o modelo matemático utilizado incluiu os efeitos fixos de grupo contemporâneo (GC, grupo genético do animal (GG, idade do animal e idade da vaca ao parto. Grupo Contemporâneo e Grupo Genético influenciaram significativamente todas as características estudadas. A idade do bezerro foi significativa para G365 e G550. A idade da vaca ao parto apresentou influência linear e quadrática sobre G550. Os animais cruzados foram 25,9 e 34,8 kg mais pesados que os puros Nelore para P365 e P550, respectivamente. Para G365 e G550, os cruzados ganharam, em média, 67 e 21 g por dia, respectivamente, a mais que os puros Nelore. Os animais F1 dos grupos 1AG1NL, 1GL1NL e 1SM1NL foram, aproximadamente, 8% superiores que demais F1, para as características estudadas, e entre esses, os grupos 1GL1NL e 1SM1NL destacaram-se até os 365 dias de idade. Entre os grupos oriundos de raças sintéticas, 1BA1NL, 1BVNL e 1CN1NL, os cruzados Canchim foram 4 a 7% superiores para as características estudadas.With the objetive to compare the genetic group

  5. Seismic imaging beneath an InSAR anomaly in eastern Washington State: Shallow faulting associated with an earthquake swarm in a low-hazard area

    Science.gov (United States)

    Stephenson, William J.; Odum, Jackson K.; Wicks, Chuck; Pratt, Thomas L.; Blakely, Richard J.

    2016-01-01

    In 2001, a rare swarm of small, shallow earthquakes beneath the city of Spokane, Washington, caused ground shaking as well as audible booms over a five‐month period. Subsequent Interferometric Synthetic Aperture Radar (InSAR) data analysis revealed an area of surface uplift in the vicinity of the earthquake swarm. To investigate the potential faults that may have caused both the earthquakes and the topographic uplift, we collected ∼3  km of high‐resolution seismic‐reflection profiles to image the upper‐source region of the swarm. The two profiles reveal a complex deformational pattern within Quaternary alluvial, fluvial, and flood deposits, underlain by Tertiary basalts and basin sediments. At least 100 m of arching on a basalt surface in the upper 500 m is interpreted from both the seismic profiles and magnetic modeling. Two west‐dipping faults deform Quaternary sediments and project to the surface near the location of the Spokane fault defined from modeling of the InSAR data.

  6. Association between Depressive Symptoms and Metabolic Syndrome in Police Officers: Results from Two Cross-Sectional Studies

    International Nuclear Information System (INIS)

    Hartley, T.A.; Fekedulegn, D.; Andrew, M.E.; Burchfiel, C.M.; Hartley, T.A.; Knox, S.S.; Barbosa-Leiker, C.; Violanti, J.M.

    2012-01-01

    Policing is one of the most dangerous and stressful occupations and such stress can have deleterious effects on health. The purpose of this study was to examine the association between depressive symptoms and metabolic syndrome (Met Syn) in male and female police officers from two study populations, Buffalo, NY and Spokane, WA. Depressive symptoms were measured using the Center for Epidemiologic Studies-Depression (CES-D) scale. Met Syn was defined using the 2005 AHA/NHBLI guidelines. Analysis of covariance was used to describe differences in number of Met Syn components across depressive symptom categories. The number of Met Syn components increased significantly across categories of CES-D for Spokane men only (p-trend = 0.003). For each 5-unit increase in CES-D score, odds increased by 47.6% for having hypertriglyceridemia, by 51.8% for having hypertension, and by 56.7% for having glucose intolerance. Exploring this association is important since both are predictors of future chronic health problems and the results could be helpful in developing future gender-specific prevention and intervention efforts among police officers

  7. Dynamic Flight Simulation Utilizing High Fidelity CFD-Based Nonlinear Reduced Order Model, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — The Nonlinear Dynamic Flight Simulation (NL-DFS) system will be developed in the Phase II project by combining the classical nonlinear rigid-body flight dynamics...

  8. Integrating Clinical Neuropsychology into the Undergraduate Curriculum.

    Science.gov (United States)

    Puente, Antonio E.; And Others

    1991-01-01

    Claims little information exists in undergraduate education about clinical neuropsychology. Outlines an undergraduate neuropsychology course and proposes ways to integrate the subject into existing undergraduate psychology courses. Suggests developing specialized audio-visual materials for telecourses or existing courses. (NL)

  9. Hoe verloopt identiteit-verificatie van online studenten?

    NARCIS (Netherlands)

    Janssen, José

    2018-01-01

    Presentatie over identiteit verificatie van online studenten tijdens een werkbezoek van NUFFIC (https://www.nuffic.nl/) aan de Open Universiteit. Topics: identiteit verificatie, vormen van authenticatie, online toetsen, toetsfraude, TeSLA instrumenten voor authenticatie en verificatie van

  10. Renewable energy in the Netherlands

    International Nuclear Information System (INIS)

    De Boer, A.; Van Gerven, B.

    2001-01-01

    In two articles an overview is given of the developments in the Netherlands with respect to renewable energy. The Dutch government aims at wind power and biomass at the expense of solar energy and heat pumps and hydroelectric power [nl

  11. Greening of the decentralized tax system in the Netherlands. Study on the further implementation of the principle 'the polluter pays'

    International Nuclear Information System (INIS)

    Blom, M.; Peelen, C.

    2005-01-01

    In the Netherlands there is not (yet) an overview of possibilities to 'green' the tax system on a decentralized level. However, a study on 'greening' the tax system resulted in a list of 22 options [nl

  12. Allocation of public and-or private responsibilities. Governance arrangements for green roofs

    NARCIS (Netherlands)

    Mees, H.L.P.

    2012-01-01

    This research was commissioned by Knowledge for Climate, Hotspot Rotterdam Region (http://knowledgeforclimate.climateresearchnetherlands.nl/hotspots/rotterdam-region), and included an international comparison of governance arrangements for the promotion of green roofs as an innovative no-regrets

  13. Adhoc Wireless Network Control: Energy Efficiency and Hidden Terminal Considerations

    Science.gov (United States)

    2009-12-01

    Pnl (t) +Bn(t), Emax ) , (57) Ynl(t+ 1) = [Ynl(t)−Rnl,in(t)] + + γnl(t), (58) Dn(t+ 1) = [Dn(t...1− δ)Bn(t)] + + ∑ l∈On Pnl (t), (59) subject to constraints Rnl,in(t) ≤ Vnl(t) +Anl(t) ∀n, l, t, P (t) ∈ PS(t), ∑ l∈On Pnl (t) ≤ min ( En(t), P̂ ) ∀n...γnl(t)] ∣ ∣ ∣ ∣ ∣ ∣ X(t)   − 2E   ∑ n,l [Unl(t)µnl (S(t),P (t))−Dn(t) Pnl (t)] ∣ ∣ ∣ ∣ ∣ ∣ X(t)  − 2E   ∑ n,l [ηYnl(t)−

  14. Sustainability effects of environment damaging subsidies. A closer look at the sustainability effects of the adjustment or abolition of environment damaging subsidies

    International Nuclear Information System (INIS)

    Van Ast, J.A.; Maas, K.E.H.; Bouma, J.J.; Baas, L.W.

    2005-10-01

    The aim of the study on the title subject is to develop a transparent integrated method to determine and analyze the environmental impacts of indirect subsidies, applied in many different sectors in the Netherlands [nl

  15. Eenzaamheid en armoede (blog)

    NARCIS (Netherlands)

    de Jong Gierveld, J.

    2017-01-01

    Blog 'Eenzaamheid en armoede' voor Coalitie Erbij van J. de Jong Gierveld binnen de Serie de Kwetsbare Samenleving, 20 oktober 2017. https://www.samentegeneenzaamheid.nl/blog/risicogroepen/veel-mensen-die-armoede-verkeren-voelen-zich-sterk-eenzaam

  16. Opportunities for smart meters in Germany

    International Nuclear Information System (INIS)

    Wolff, J.

    2010-10-01

    Germany has the ambitious goal of lowering its CO2 emission with 80 percent until 2050 as compared to 1990. Sustainable energy and the deployment of smart meters are starting to play increasingly important roles. [nl

  17. Pääsküla sõjaväeobjekti jääkreostus ning piirkonna edasise kasutamise perspektiivid / Triin Uudeväli, Anto Raukas

    Index Scriptorium Estoniae

    Uudeväli, Triin

    2004-01-01

    Pääskülas asunud NL-i raketijuhtimisekeskuse ja sideväeosa poolt tekitatud keskkonnareostuse hindamisest, likvideerimisest ning ettepanekutest territooriumi edasiseks kasutamiseks. Kaart. Skeem. Fotod

  18. Structure of exotic nuclei and superheavy elements in meson field theory

    International Nuclear Information System (INIS)

    Linn, Khin Nyan

    2008-07-01

    In this work the nuclear structure of exotic nuclei and superheavy nuclei is studied in a relativistic framework. In the relativistic mean-field (RMF) approximation, the nucleons interact with each other through the exchange of various effective mesons (scalar, vector, isovector-vector). Ground state properties of exotic nuclei and superheavy nuclei are studied in the RMF theory with the three different parameter sets (ChiM,NL3,NL-Z2). Axial deformation of nuclei within two drip lines are performed with the parameter set (ChiM). The position of drip lines are investigated with three different parameter sets (ChiM,NL3,NL-Z2) and compared with the experimental drip line nuclei. In addition, the structure of hypernuclei are studied and for a certain isotope, hyperon halo nucleus is predicted. (orig.)

  19. Detailed Analysis of Configuration Interaction and Calculation of Radiative Transition Rates in Seven Times Ionized Tungsten (W VIII

    Directory of Open Access Journals (Sweden)

    Jérôme Deprince

    2015-06-01

    Full Text Available A new set of oscillator strengths and transition probabilities for EUV spectral lines of seven times ionized tungsten (W VIII is reported in the present paper. These results have been obtained using the pseudo-relativistic Hartree-Fock (HFR method combined with a semi-empirical optimization of the radial parameters minimizing the discrepancies between computed energy levels and available experimental data. The final physical model considered in the calculations has been chosen further to a detailed investigation of the configuration interaction in this atomic system characterized by complex configurations of the type 4f145s25p5, 4f145s25p4nl, 4f145s5p6, 4f135s25p6, 4f135s25p5nl and 4f125s25p6nl (nl = 5d, 6s.

  20. The climate controversy demands substantive discussion. 'Climatic change sceptics' opposite 'greenhouse effect believers'

    International Nuclear Information System (INIS)

    Thoenes, D.; Labohm, H.

    2006-01-01

    With the aim to inform policymakers an overview is given of the arguments that are used by climatic change sceptics and greenhouse effect believers, and on which arguments do they agree or disagree [nl

  1. Transparency in population forecasting : Methods for fitting and projecting fertility, mortality and migration

    NARCIS (Netherlands)

    Beer, Josephus Adrianus Antionius de

    2011-01-01

    Transparantie in bevolkingsprognoses Methoden voor het schatten en voorspellen van vruchtbaarheid, sterfte en migratie Joop de Beer Nederlands Interdisciplinair Demografisch Instituut, Den Haag beer@nidi.nl Korte samenvatting Bevolkingsprognoses kunnen worden verbeterd door een internationale

  2. Hydroelectric power is green, although controversial

    International Nuclear Information System (INIS)

    Schulp, A.

    2003-01-01

    Hydroelectric power is worldwide the most important source of renewable energy. Still, it has some controversial aspects, which are briefly discussed in this article, focusing on Belgium and the Netherlands [nl

  3. The role of the Dutch government in a liberalized energy market. Advice to the Minister of Economic Affairs

    International Nuclear Information System (INIS)

    2001-01-01

    According to the Dutch General Energy Council the government can play an essential role in protecting the public interests in a free energy market. Also, the Council indicates how those interests can be assured and guaranteed. 5 refs [nl

  4. The HVT technique and the 'uncertainty' relation for central potentials

    International Nuclear Information System (INIS)

    Grypeos, M E; Koutroulos, C G; Oyewumi, K J; Petridou, Th

    2004-01-01

    The quantum mechanical hypervirial theorems (HVT) technique is used to treat the so-called 'uncertainty' relation for quite a general class of central potential wells, including the (reduced) Poeschl-Teller and the Gaussian one. It is shown that this technique is quite suitable in deriving an approximate analytic expression in the form of a truncated power series expansion for the dimensionless product P nl ≡ (r 2 ) nl (p 2 ) nl /ℎ 2 , for every (deeply) bound state of a particle moving non-relativistically in the well, provided that a (dimensionless) parameter s is sufficiently small. Attention is also paid to a number of cases, among the limited existing ones, in which exact analytic or semi-analytic expressions for P nl can be derived. Finally, numerical results are given and discussed

  5. Gap in air pollution reduction measures

    International Nuclear Information System (INIS)

    Kamphuis, E.; Spijker, E.

    2006-01-01

    The air quality dossier in the Netherlands requires drastic cleaning of the vehicles fleet. However, the present measures are too much focused on the installation and use of soot filters. Other options to improve the air quality are discussed [nl

  6. Living green saves money. Personal environmental burden test

    International Nuclear Information System (INIS)

    2003-01-01

    Based on a number of questions one can calculate the environmental burden of a lifestyle and determine which measures can unburden the environment and how much money can be saved by changing a lifestyle [nl

  7. Thirty years nuclear energy. 240,000 years of nuclear waste. Why Greenpeace campaigns against nuclear energy

    International Nuclear Information System (INIS)

    Teule, R.

    2004-01-01

    A brief overview is given of the arguments that Greenpeace has against nuclear energy, and why this environmental organization campaigns against the processing of nuclear waste and transportation of Dutch nuclear waste to France [nl

  8. Comparing quality of dying and death perceived by family members and nurses for patients dying in US and Dutch ICUs

    DEFF Research Database (Denmark)

    Gerritsen, Rik T; Koopmans, Matty; Hofhuis, José G M

    2017-01-01

    BACKGROUND: The Quality of Dying and Death (QODD) questionnaire is used as a self-reported measure to allow families and clinicians to assess patients' quality of dying and death. We evaluated end-of-life (EOL) experiences as measured by the QODD completed by families and nurses in the United...... States (US) and the Netherlands (NL) to explore similarities and differences in these experiences and identify opportunities for improving EOL care. METHODS: Questionnaire data were gathered from family members of patients dying in the ICU and nurses caring for these patients. In NL, data were gathered.......0025). The family-assessed overall QODD score (medians [IQR]) was the same in both countries: NL 9 [8-10], US 8[5-10]. US family members rated the quality of two items higher than NL families: "time spent with loved ones" and "time spent alone". Nurse-assessed QODD ratings varied: the single-item QODD summary score...

  9. Japanese Heraldry: Who Am I?

    Science.gov (United States)

    Zeni, Claire M.

    1991-01-01

    Uses Japanese family crests to motivate students to construct a family history. Includes background information on Japanese history and culture. Provides an outline for the student research project. Supplies a list of Japanese emblems and their symbolism. (NL)

  10. Dicty_cDB: VHH667 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available n**yhrrsqwqsl*slpqtilfrslpssp*g*lifstwwyesrri*scrnrpr*ilyr ctrdiytl*r*gsqerg*rpsr*gwlr*y--- ---cfvx**vg*yctxxrf...itr*cwwcw*xsyqsnfn*ngwyerqexrfhhwxyq*tryh rssyppsrxfrsthlhsitrftixcchfqglfq*ixsrqgcrfxifgskxsrfxwxrfn* nl

  11. Environmental effects of indirect subsidies. The development and use of a policy-oriented methodology

    International Nuclear Information System (INIS)

    Van Beers, C.P.; De Moor, A.P.G.; Van den Bergh, J.C.J.M.; Oosterhuis, F.H.

    2002-12-01

    The aim of the study on the title subject is to develop a transparent integrated method to determine and analyze the environmental impacts of indirect subsidies, applied in the sectors agriculture, energy, mobility, and tourism [nl

  12. 76 FR 68720 - Takes of Marine Mammals Incidental to Specified Activities; Low-Energy Marine Geophysical Survey...

    Science.gov (United States)

    2011-11-07

    ... seal (Monachus schauinslandi). The North Pacific right whale (Eubalaena japonica), listed as endangered... sperm whale (Kogia Deep waters off the NA NL NC 0 breviceps). shelf. 3.19 1.76 Dwarf sperm whale (Kogia...

  13. Idols of the Psychologist: Johannes Linschoten and The demise Of Phenomenological Psychology In The Netherlands

    NARCIS (Netherlands)

    Van Hezewijk, René; Stam, Henderikus J.

    2008-01-01

    The present version is the definite version of the manuscript. The article as published may be slightly different from this version. Please contact the first author for a reprint (rene.vanhezewijk@ou.nl)

  14. NOx emission trade. What is the state-of-the-art?

    International Nuclear Information System (INIS)

    Witkamp, J.

    2003-01-01

    In Leiden, Netherlands, 28 November 2002, a symposium was organized on the subject of NOx emission trade in preparation of a NOx emission trade system. In this article an overview is given of the developments so far [nl

  15. Training and Development and the Youth Problem

    Science.gov (United States)

    Nadler, David

    1970-01-01

    A George Washington University senior who attended the 25th Anniversary Conference of ASTD was struck by the absence of thought and time devoted to the problem of young people entering the work force. (NL)

  16. Uric acid - blood

    Science.gov (United States)

    ... acid in blood Images Blood test Uric acid crystals References Edwards NL. Crystal deposition diseases. In: Goldman L, Schafer AI, eds. ... M. is among the first to achieve this important distinction for online health information and services. Learn ...

  17. Hoe verloopt identiteit-verificatie van online studenten?

    OpenAIRE

    Janssen, José

    2018-01-01

    Presentatie over identiteit verificatie van online studenten tijdens een werkbezoek van NUFFIC (https://www.nuffic.nl/) aan de Open Universiteit. Topics: identiteit verificatie, vormen van authenticatie, online toetsen, toetsfraude, TeSLA instrumenten voor authenticatie en verificatie van auteurschap.

  18. Climatic change and tourism. Survey of potential consequences for tourism in the Netherlands

    International Nuclear Information System (INIS)

    Amelung, B.

    2002-01-01

    A description is given of a project in which an integrated analysis will be given of the possible consequences of climatic change for natural systems, economical sectors, land use, health and recreation in the Netherlands [nl

  19. Nitrogen deposition and traffic. State-of-the-art

    International Nuclear Information System (INIS)

    Teeuwisse, S.

    2010-01-01

    Nitrogen deposition is caused, among other things, by road traffic. This article addresses the relation between traffic and nitrogen deposition and the manner in which the contribution of traffic to nitrogen deposition can be quantified. [nl

  20. Neurotoxic shellfish poisoning: A review

    NARCIS (Netherlands)

    Apeldoorn ME van; Egmond HP van; Speijers GJA; CSR; ARO

    2001-01-01

    Dit literatuuroverzicht bevat informatie betreffende het "neurotoxic shellfish poisoning" (NSP) syndroom en de veroorzakende toxines, nl.de brevetoxines, welke geproduceerd worden door de dinoflagellaat Gymnodinium breve. Chemische structuren en detectie-methodes van de brevetoxines,

  1. Bistand til risikovurdering (evt. ændring af tidligere risikovurdering). Zea mays (1507). Supplerende oplysninger om den molekylære karakterisering af 1507 majsen. Modtaget 26-08-2004, deadline 26-09-2004, svar 21-09-2004

    DEFF Research Database (Denmark)

    Kjellsson, Gøsta; Damgaard, Christian

    2004-01-01

    "Mail: Vi har nu set det suplerende materiale igennem for B-notifikationen C/NL/00/10 igennem. De nye oplysninger giver ikke anledning til nogen ændringer i den tidligere fremsendte risikovurdering."...

  2. Waste collection : a new topic for research in city logistics

    NARCIS (Netherlands)

    de Rijke, Simon; Colstee, Jan-Willem

    2017-01-01

    Waste collection is an important volume in city logistics today. In the LEVV-LOGIC project the Amsterdam University of Applied Sciences (NL) performed research on waste and the potential use of light commercial vehicles for waste collection in cities.

  3. [Responses of rice growth and development to elevated near-surface layer ozone (O3) concentration: a review].

    Science.gov (United States)

    Yang, Lian-xin; Wang, Yu-long; Shi, Guang-yao; Wang, Yun-xia; Zhu, Jian-guo

    2008-04-01

    Ozone (O3) is recognized as one of the most important air pollutants. At present, the worldwide average tropospheric O3 concentration has been increased from an estimated pre-industrial level of 38 nl L(-1) (25-45 nl L(-1), 8-h summer seasonal average) to approximately 50 nl L(-1) in 2000, and to 80 nl L(-1) by 2100 based on most pessimistic projections. Oryza sativa L. (rice) is the most important grain crop in the world, and thus, to correctly evaluate how the elevated near-surface layer O3 concentration will affect the growth and development of rice is of great significance. This paper reviewed the chamber (including closed and open top chamber)-based studies about the effects of atmospheric ozone enrichment on the rice visible injury symptoms, photosynthesis, water relationship, phenology, dry matter production and allocation, leaf membrane protective system, and grain yield and its components. Further research directions in this field were discussed.

  4. Dicty_cDB: AFO328 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available hmi*stifeviqiifnkqk*nlik*nl*kti*nknkkqsnknikkk--- ---xxxxxxxxxxxxivxxxxxxxxxxwllxxxxxxvxxvxihylilxxxlvlxxqxlvx xxx...alnqsngsgneqvvaapsv Frame B: tvgllel*pft*ysrqylksfk*flinknki**NKIYRKQYKIKTKNKVIKILKKK--- ---xxxxxxxxxxxx*xxxsxxxxyxxgyxxxxxxxxkxxx...fii*y*xfxwycxxnx*xx xxxkxxxq*ix*kxngs*iilftstinsnfktyyyxcn*ykykykhmn*ihy*nq*lhym ieqln

  5. Make way for the climate. National adaptation strategy. The policy paper

    International Nuclear Information System (INIS)

    2007-11-01

    The policy paper is a background document of the interdepartmental memorandum 'Make way for climate', in which the outline is described for a national strategy for adaptation to the consequences of climate change. [mk] [nl

  6. Make way for the climate. National adaptation strategy. The interdepartmental memorandum

    International Nuclear Information System (INIS)

    2007-11-01

    This memorandum describes the outline of a national strategy for adaptation to the consequences of climate change. The memorandum is the first report of the Adapting Spatial Planning to Climate Change programme (ARK). [mk] [nl

  7. Solar Imagery - Composites - Full Sun Drawings - Boulder

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Synoptic Analysis Drawings, also known as Neutral Line (NL) drawings, are produced each day by space weather forecaster at the NOAA National Weather Service (NWS)...

  8. Comparison of equivalent linear and non linear methods on ground response analysis: case study at West Bangka site

    International Nuclear Information System (INIS)

    Eko Rudi Iswanto; Eric Yee

    2016-01-01

    Within the framework of identifying NPP sites, site surveys are performed in West Bangka (WB), Bangka-Belitung Island Province. Ground response analysis of a potential site has been carried out using peak strain profiles and peak ground acceleration. The objective of this research is to compare Equivalent Linear (EQL) and Non Linear (NL) methods of ground response analysis on the selected NPP site (West Bangka) using Deep Soil software. Equivalent linear method is widely used because requires soil data in simple way and short time of computational process. On the other hand, non linear method is capable of representing the actual soil behaviour by considering non linear soil parameter. The results showed that EQL method has similar trends to NL method. At surface layer, the acceleration values for EQL and NL methods are resulted as 0.425 g and 0.375 g respectively. NL method is more reliable in capturing higher frequencies of spectral acceleration compared to EQL method. (author)

  9. The harvest of the environment

    International Nuclear Information System (INIS)

    Boersema, J.; Pulles, T.; Van der Straaten, J.; Bertels, J.

    2003-01-01

    This last issue of the journal 'Milieu' (Environment) contains 20 articles, based on dissertations on several subjects within the environmental sciences, which were published in the Netherlands in the last ten years [nl

  10. Impacts of supplementary measures on the bottlenecks of air quality

    International Nuclear Information System (INIS)

    Beck, J.P.; Annema, J.A.; Blom, W.F.; Brink, R.M.M. Van den; Hammingh, P.; Smeets, W.L.M.

    2005-04-01

    The proposals of the Dutch government to reduce the emission from traffic do and will improve the air quality in the Netherlands but are not yet sufficient to meet the European emission standards for particulates and nitrogen dioxide [nl

  11. Broadband from the socket and privatization of power distribution networks

    International Nuclear Information System (INIS)

    Aalbers, R.; Baarsma, B.; Poort, J.

    2005-01-01

    Attention is paid to the consequences for the Dutch market of the recommendation of the European Commission to introduce Power Line Communication (PLC) in the EU member states. PLC makes it possible to access the internet via sockets [nl

  12. Price transparency on the market for automotive fuels. Final report

    International Nuclear Information System (INIS)

    Meindert, L.; Van Schijndel, M.; Volkerink, B.

    2011-05-01

    The objective of this study is to answer the main question: which bottlenecks may obstruct the road to up-to-date, reliable and fully market covering price comparison services for the Dutch market for automotive fuels. [nl

  13. Renewable energy in Dutch households. An online survey

    International Nuclear Information System (INIS)

    Mors, B.; Both, J.

    2004-01-01

    The main aim of the title survey was to find out how households in the Netherlands can be interested and involved in the use of renewable energy, in particular biomass, wind power and solar energy [nl

  14. Music Education and Medicine: Music and the Neurology of Time.

    Science.gov (United States)

    Wilson, Frank R.

    1991-01-01

    Explores how the body's biological clock affects the way musicians practice and perform. Delineates questions concerning this phenomenon. Discusses the implications for music teaching and focuses on areas for collaborative research between neurology researchers and music educators. (NL)

  15. Soluble ectodomain of neuroligin 1 decreases synaptic activity by activating metabotropic glutamate receptor 2

    DEFF Research Database (Denmark)

    Gjørlund, Michelle D.; Carlsen, Eva Maria Meier; Kønig, Andreas Bay

    2017-01-01

    -dependent manner, releasing a soluble extracellular fragment and membrane-tethered C-terminal fragment. The cleavage of NL1 depresses synaptic transmission, but the mechanism by which this occurs is unknown. Metabotropic glutamate receptor 2 (mGluR2) are located primarily at the periphery of presynaptic terminals......, where they inhibit the formation of cyclic adenosine monophosphate (cAMP) and consequently suppress the release of glutamate and decrease synaptic transmission. In the present study, we found that the soluble ectodomain of NL1 binds to and activates mGluR2 in both neurons and heterologous cells......, resulting in a decrease in cAMP formation. In a slice preparation from the hippocampus of mice, NL1 inhibited the release of glutamate from mossy fibers that project to CA3 pyramidal neurons. The presynaptic effect of NL1 was abolished in the presence of a selective antagonist for mGluR2. Thus, our data...

  16. Robotica

    NARCIS (Netherlands)

    Bosch, T.; Korte, E. de

    2016-01-01

    Robots zijn hot en de technologische ontwikkelingen gaan zeer snel. Het vakgebied Human Factors speelt een grote rol bij het realiseren van een goede interactie tussen mens en robot voor verschillende vormen van robotisering. www.humanfactors.nl

  17. The eco-efficiency of tourism. Decrease of effects of tourism on climate change

    International Nuclear Information System (INIS)

    Peeters, P.

    2004-01-01

    Without governmental regulations emission of greenhouses, caused by tourism, will most likely not be reduced. In particular, reduction of emission is not feasible without decrease of air transport for tourism activities [nl

  18. Health Benefits of Water-based Exercise

    Science.gov (United States)

    ... In Chapter 2: Physical Activity Has Many Health Benefits. 2009. Chase NL, Sui X, Blair SN. 2008. Swimming and all-cause mortality risk compared with running, walking, and sedentary habits in men. Int J of ...

  19. Epitope-Independent Purification of Native-Like Envelope Trimers from Diverse HIV-1 Isolates.

    Science.gov (United States)

    Verkerke, Hans P; Williams, James A; Guttman, Miklos; Simonich, Cassandra A; Liang, Yu; Filipavicius, Modestas; Hu, Shiu-Lok; Overbaugh, Julie; Lee, Kelly K

    2016-10-15

    Soluble forms of trimeric HIV-1 envelope glycoprotein (Env) have long been sought as immunogens and as reagents for analysis of Env structure and function. Isolation of trimers that mimic native Env, derived from diverse viruses, however, represents a major challenge. Thus far, the most promising native-like (NL) structures have been obtained by engineering trimer-stabilizing mutations, termed SOSIP, into truncated Env sequences. However, the abundances of NL trimeric conformers vary among Envs, necessitating purification by monoclonal antibodies (MAbs) like PGT145, which target specific epitopes. To surmount this inherent limitation, we developed an approach that uses lectin affinity chromatography, ion-exchange chromatography, hydrophobic-interaction chromatography (HIC), and size exclusion chromatography (SEC) to isolate NL trimers from nonnative Env species. We validated this method with SOSIP trimers from HIV-1 clades A and B. Analyses by SEC, blue native PAGE, SDS-PAGE, and dynamic light scattering indicated that the resulting material was homogeneous (>95% pure), fully cleaved, and of the appropriate molecular weight and size for SOSIP trimers. Negative-stain electron microscopy further demonstrated that our preparations were composed of NL trimeric structures. By hydrogen/deuterium-exchange mass spectrometry, these HIC-pure trimers exhibited structural organization consistent with NL trimers and inconsistent with profiles seen in nonnative Envs. Screened for antigenicity, some Envs, like BS208.b1 and KNH1144 T162A, did not present the glycan/quaternary structure-dependent epitope for PGT145 binding, suggesting that these SOSIPs would be challenging to isolate by existing MAb affinity methods. By selecting based on biochemical rather than antigenic properties, our method offers an epitope-independent alternative to MAbs for isolation of NL Env trimers. The production and purification of diverse soluble Env trimers that maintain native-like (NL) structure

  20. Multidrug resistant 2009 A/H1N1 influenza clinical isolate with a neuraminidase I223R mutation retains its virulence and transmissibility in ferrets.

    Directory of Open Access Journals (Sweden)

    Erhard van der Vries

    2011-09-01

    Full Text Available Only two classes of antiviral drugs, neuraminidase inhibitors and adamantanes, are approved for prophylaxis and therapy against influenza virus infections. A major concern is that influenza virus becomes resistant to these antiviral drugs and spreads in the human population. The 2009 pandemic A/H1N1 influenza virus is naturally resistant to adamantanes. Recently a novel neuraminidase I223R mutation was identified in an A/H1N1 virus showing cross-resistance to the neuraminidase inhibitors oseltamivir, zanamivir and peramivir. However, the ability of this virus to cause disease and spread in the human population is unknown. Therefore, this clinical isolate (NL/2631-R223 was compared with a well-characterized reference virus (NL/602. In vitro experiments showed that NL/2631-I223R replicated as well as NL/602 in MDCK cells. In a ferret pathogenesis model, body weight loss was similar in animals inoculated with NL/2631-R223 or NL/602. In addition, pulmonary lesions were similar at day 4 post inoculation. However, at day 7 post inoculation, NL/2631-R223 caused milder pulmonary lesions and degree of alveolitis than NL/602. This indicated that the mutant virus was less pathogenic. Both NL/2631-R223 and a recombinant virus with a single I223R change (recNL/602-I223R, transmitted among ferrets by aerosols, despite observed attenuation of recNL/602-I223R in vitro. In conclusion, the I223R mutated virus isolate has comparable replicative ability and transmissibility, but lower pathogenicity than the reference virus based on these in vivo studies. This implies that the 2009 pandemic influenza A/H1N1 virus subtype with an isoleucine to arginine change at position 223 in the neuraminidase has the potential to spread in the human population. It is important to be vigilant for this mutation in influenza surveillance and to continue efforts to increase the arsenal of antiviral drugs to combat influenza.

  1. Taxonomy Icon Data: yellow fever mosquito [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available yellow fever mosquito Aedes aegypti Arthropoda Aedes_aegypti_L.png Aedes_aegypti_NL.png Aedes_aegypt...i_S.png Aedes_aegypti_NS.png http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Aedes+aegypti...&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Aedes+aegypti&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Aedes+aegyp...ti&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Aedes+aegypti&t=NS ...

  2. Taxonomy Icon Data: Lotus japonicus [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available Lotus japonicus Lotus japonicus Lotus_japonicus_L.png Lotus_japonicus_NL.png Lotus_japonicus_S.png Lotus_jap...onicus_NS.png http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Lotus+japonicus&t=L ...http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Lotus+japonicus&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Lotus+jap...onicus&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Lotus+japonicus&t=NS ...

  3. Taxonomy Icon Data: oriental silverfish [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available oriental silverfish Ctenolepisma villosa Arthropoda Ctenolepisma_villosa_L.png Ctenolepisma_villosa..._NL.png Ctenolepisma_villosa_S.png Ctenolepisma_villosa_NS.png http://biosciencedbc.jp/taxon...omy_icon/icon.cgi?i=Ctenolepisma+villosa&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Ctenolepisma+villosa...&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Ctenolepisma+villosa...&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Ctenolepisma+villosa&t=NS ...

  4. Taxonomy Icon Data: hemichordates (Acorn worm) [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available hemichordates (Acorn worm) Glandiceps hacksi Hemichordata Glandiceps_hacksi_L.png Glandiceps_hack...si_NL.png Glandiceps_hacksi_S.png Glandiceps_hacksi_NS.png http://biosciencedbc.jp/taxonomy_ic...on/icon.cgi?i=Glandiceps+hacksi&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Glandiceps+hacksi&t=NL ...http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Glandiceps+hacksi&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Glandiceps+hacksi&t=NS ...

  5. Taxonomy Icon Data: Sitka spruce [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available Sitka spruce Picea sitchensis Picea_sitchensis_L.png Picea_sitchensis_NL.png Picea_sitchen...sis_S.png Picea_sitchensis_NS.png http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Picea+sitchensis&t...=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Picea+sitchensis&t=NL http://biosciencedbc.jp/taxonomy_i...con/icon.cgi?i=Picea+sitchensis&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Picea+sitchensis&t=NS ...

  6. Geluidsexpositie bij Gebruik van Otoplastieken met Communicatie (Sound Exposure Level of F-16 Crew Chiefs Using Custom Molded Communications Earplugs)

    Science.gov (United States)

    2008-10-01

    TNO Defensie en Veiligheid dr. ir. M.M.J. Houben Auteur ONGERUBRICEERD REPORT DOCUMENTATION PAGE (MOD-NL) 1. DEFENCE REPORT NO (MOD-NL) TD2008...that this Technical Document has the Distribution Statement checked below. The current distribution for this document can be found in the DTIC...STATEMENT B. Distribution authorized to U.S. Government agencies only. Other requests for this document shall be referred to controlling office

  7. Growdon Gate/Road Relocation and Property Acquisition Environmental Assessment. Volume 1

    Science.gov (United States)

    2012-11-01

    the Texas Air National Guard 149th Fighter Wing, the 59th Medical Wing, the Air Force Intelligence , Surveillance and Reconnaissance Agency, and the...2011c, 2012a, 2012b). The State of Texas lists four bird species and two (extirpated) mammal species as endangered and four reptile , four bird, and...salamander Eurycea neotene Under review 2 Rare Reptiles Texas horned lizard Phrynosoma cornutum NL T Texas indigo snake Drymarchon melanurus erebennus NL

  8. Epitope-Independent Purification of Native-Like Envelope Trimers from Diverse HIV-1 Isolates

    OpenAIRE

    Verkerke, Hans P.; Williams, James A.; Guttman, Miklos; Simonich, Cassandra A.; Liang, Yu; Filipavicius, Modestas; Hu, Shiu-Lok; Overbaugh, Julie; Lee, Kelly K.

    2016-01-01

    Soluble forms of trimeric HIV-1 envelope glycoprotein (Env) have long been sought as immunogens and as reagents for analysis of Env structure and function. Isolation of trimers that mimic native Env, derived from diverse viruses, however, represents a major challenge. Thus far, the most promising native-like (NL) structures have been obtained by engineering trimer-stabilizing mutations, termed SOSIP, into truncated Env sequences. However, the abundances of NL trimeric conformers vary among En...

  9. Regional analysis of FDG and PIB-PET images in normal aging, mild cognitive impairment, and Alzheimer's disease

    International Nuclear Information System (INIS)

    Li, Yi; Rinne, Juha O.; Kemppainen, Nina; Naagren, Kjell; Mosconi, Lisa; Pirraglia, Elizabeth; Rusinek, Henry; DeSanti, Susan; Kim, Byeong-Chae; Tsui, Wai; Leon, Mony J. de

    2008-01-01

    The objective of the study is to compare the diagnostic value of regional sampling of the cerebral metabolic rate of glucose metabolism (MRglc) using [18F]-fluoro-2-deoxyglucose ([18F]FDG)-positron emission tomography (PET) and amyloid-beta pathology using Pittsburgh Compound-B ([11C]PIB)-PET in the evaluation of patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI) compared to normal elderly (NL). AD patients, 7NL, 13MCI, and 17, received clinical, neuropsychological, magnetic resonance imaging (MRI), FDG, and PIB-PET exams. Parametric images of PIB uptake and MRglc were sampled using automated regions-of-interest (ROI). AD showed global MRglc reductions, and MCI showed reduced hippocampus (HIP) and inferior parietal lobe (IP) MRglc compared to NL. On PIB, AD patients showed significantly increased uptake in the middle frontal gyrus (MFG), posterior cingulate cortex (PCC), and IP (ps<0.05). PIB uptake in MCI subjects was either AD or NL-like. HIP MRglc and MFG PIB uptake were the best discriminators of NL from MCI and NL from AD. These two best measures showed high diagnostic agreement for AD (94%) and poor agreement for MCI (54%). For the NL vs. MCI discrimination, combining the two best measures increased the accuracy for PIB (75%) and for FDG (85%) to 90%. For AD, the pattern of regional involvement for FDG and PIB differ, but both techniques show high diagnostic accuracy and 94% case by case agreement. In the classification of NL and MCI, FDG is superior to PIB, but there is only 54% agreement at a case level. Combining the two modalities improves the diagnostic accuracy for MCI. (orig.)

  10. Regional analysis of FDG and PIB-PET images in normal aging, mild cognitive impairment, and Alzheimer's disease

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yi [New York University School of Medicine, New York, NY (United States); Qilu hospital Shandong University, Jinan (China); HN400 NYU School of Medicine, Center for Brain Health, Department of Psychiatry, New York, NY (United States); Rinne, Juha O.; Kemppainen, Nina; Naagren, Kjell [Turku PET Centre, University of Turku, Turku (Finland); Mosconi, Lisa; Pirraglia, Elizabeth; Rusinek, Henry; DeSanti, Susan [New York University School of Medicine, New York, NY (United States); Kim, Byeong-Chae [New York University School of Medicine, New York, NY (United States); Chonnam National University Medical School, Department of Neurology, Gwangju (Korea); Tsui, Wai [New York University School of Medicine, New York, NY (United States); Nathan Kline Institute, Orangeburg, NY (United States); Leon, Mony J. de [New York University School of Medicine, New York, NY (United States); Nathan Kline Institute, Orangeburg, NY (United States); HN400 NYU School of Medicine, Center for Brain Health, Department of Psychiatry, New York, NY (United States)

    2008-12-15

    The objective of the study is to compare the diagnostic value of regional sampling of the cerebral metabolic rate of glucose metabolism (MRglc) using [18F]-fluoro-2-deoxyglucose ([18F]FDG)-positron emission tomography (PET) and amyloid-beta pathology using Pittsburgh Compound-B ([11C]PIB)-PET in the evaluation of patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI) compared to normal elderly (NL). AD patients, 7NL, 13MCI, and 17, received clinical, neuropsychological, magnetic resonance imaging (MRI), FDG, and PIB-PET exams. Parametric images of PIB uptake and MRglc were sampled using automated regions-of-interest (ROI). AD showed global MRglc reductions, and MCI showed reduced hippocampus (HIP) and inferior parietal lobe (IP) MRglc compared to NL. On PIB, AD patients showed significantly increased uptake in the middle frontal gyrus (MFG), posterior cingulate cortex (PCC), and IP (ps<0.05). PIB uptake in MCI subjects was either AD or NL-like. HIP MRglc and MFG PIB uptake were the best discriminators of NL from MCI and NL from AD. These two best measures showed high diagnostic agreement for AD (94%) and poor agreement for MCI (54%). For the NL vs. MCI discrimination, combining the two best measures increased the accuracy for PIB (75%) and for FDG (85%) to 90%. For AD, the pattern of regional involvement for FDG and PIB differ, but both techniques show high diagnostic accuracy and 94% case by case agreement. In the classification of NL and MCI, FDG is superior to PIB, but there is only 54% agreement at a case level. Combining the two modalities improves the diagnostic accuracy for MCI. (orig.)

  11. Upconversion of whistler waves by gyrating ion beams in a plasma

    Indian Academy of Sciences (India)

    where we have assumed ions to have single charge, using ne and n1 in the Poisson's equation,. ∇2φ = 4πe(ne − ni). (13). We may get εφ = −χeφp. (14). The low-frequency density perturbation n couples to the oscillatory velocity v0 to produce a non-linear side-band current (ne · v0)/2 and a density perturbation nNL. 1 . nNL.

  12. Taxonomy Icon Data: aye-aye [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available aye-aye Daubentonia madagascariensis Chordata/Vertebrata/Mammalia/Theria/Eutheria/Primate Daubentonia_madaga...scariensis_L.png Daubentonia_madagascariensis_NL.png Daubentonia_madagascariensis_S.png Daubentonia_madagasc...ariensis_NS.png http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Daubentonia+madagascar...iensis&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Daubentonia+madagascar...iensis&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Daubentonia+madagascariensis&t=S http://bi

  13. Cyanobacterial Occurrence and Diversity in Seagrass Meadows in ...

    African Journals Online (AJOL)

    Oscillatoria, Lyngbya and Spirulina were the dominant cyanobacterial genera. Cyanobacterial coverage was higher in Mjimwema (31–100%) than in Ocean Road (0–60%). The levels of nutrients in tidal pool waters at Ocean Road ranged from 0.45–1.03 μmol NO3 -N/l, 0.19–0.27 μmol NO2 -N/l and 0.03–0.09 μmol PO4 ...

  14. Detecting Malicious Tweets in Twitter Using Runtime Monitoring With Hidden Information

    Science.gov (United States)

    2016-06-01

    by using natural language (NL) and associated formal specifications. We then specified visible and hidden parameters, which are used for subsequent...and verify the system. In the deterministic part, we determined assertions by using natural language (NL) and associated formal specifications. We...They are: 1. For about one out of five ISIS-supporter accounts, the primary language is English (73% Arabic, 18% English , and 6% French). It is common

  15. Taxonomy Icon Data: Aquilegia formosa [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available Aquilegia formosa Aquilegia formosa Aquilegia_formosa_L.png Aquilegia_formosa_NL.png Aquileg...ia_formosa_S.png Aquilegia_formosa_NS.png http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Aquilegi...a+formosa&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Aquilegia+formosa&t=NL http://biosciencedbc.j...p/taxonomy_icon/icon.cgi?i=Aquilegia+formosa&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Aquilegia+formosa&t=NS ...

  16. Winning strategies for pseudo-telepathy games using single non-local box

    International Nuclear Information System (INIS)

    Kunkri, S.; Kar, G.; Ghosh, S.; Roy, A.

    2006-12-01

    Using a single NL-box, a winning strategy is given for the impossible colouring pseudo-telepathy game for the set of vectors having Kochen-Specker property in four dimension. A sufficient condition given regarding the structure of the impossible colouring pseudo-telepathy game for general d-dimension. A winning strategy for this game is then described with single use of NL-box. (author)

  17. Cluster knockout reactions

    Indian Academy of Sciences (India)

    2014-04-07

    Apr 7, 2014 ... (figure 2), the corresponding α–α t-matrix effective interactions are seen to be widely different (figure 3). 2. Formalism. The finite-range transition matrix element T n,l. BA in the triple differential cross-section [13], d3σ d 1d 2dE1. = Fkin × Sl × |T n,l. BA (kf 1, kf 2, ki)|2 for the (α, 2α) cluster knockout reactions is ...

  18. Control of Circadian Behavior by Transplanted Suprachiasmatic Nuclei.

    Science.gov (United States)

    1994-09-02

    Ihara NL (in press) The tau mutation destabilizes the circadian system of golden hamste,’s Fifth Sapporo Symposium on Biological Rhythms Hokkaido...Shimomura K and Ihara NL (in press) The tau mutation destabilizes the circadian system of golden hamsters Fifth Sapporo Symposium oh Biological Rhythms...Switzerland, April 5 University of Pisa, Dipartimento di Scienze del Comportamento Animale e dell’Uomo, invited lecture: "Circadian Organization in the

  19. Radial, sideward and elliptic flow at AGS energies

    Indian Academy of Sciences (India)

    the sideward flow, the elliptic flow and the radial transverse mass distribution of protons data at. AGS energies. In order to ... data on both sideward and elliptic flow, NL3 model is better at 2 A¡GeV, while NL23 model is at 4–8. A¡GeV. ... port approach RBUU which is based on a coupled set of covariant transport equations for.

  20. Taxonomy Icon Data: Eastern Gorilla [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available te Gorilla_beringei_L.png Gorilla_beringei_NL.png Gorilla_beringei_S.png Gorilla_beringei_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Gorilla+beringei&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=...Gorilla+beringei&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Gorilla+be...ringei&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Gorilla+beringei&t=NS ...

  1. Taxonomy Icon Data: mandrill [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available drillus_sphinx_L.png Mandrillus_sphinx_NL.png Mandrillus_sphinx_S.png Mandrillus_sphinx_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Mandrillus+sphinx&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=M...andrillus+sphinx&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Mandrillus...+sphinx&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Mandrillus+sphinx&t=NS ...

  2. Taxonomy Icon Data: Danio rerio [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available io_NL.png Danio_rerio_S.png Danio_rerio_NS.png http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Danio+rerio&...t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Danio+rerio&t=NL http://biosciencedbc.jp/taxonomy_icon/...icon.cgi?i=Danio+rerio&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Danio...+rerio&t=NS http://togodb.biosciencedbc.jp/togodb/view/taxonomy_icon_comment_en?species_id=92 ...

  3. Taxonomy Icon Data: Ciona intestinalis (Sea squirt) [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available ttp://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Ciona+intestinalis&t=L http://biosciencedbc.jp/taxonomy_icon.../icon.cgi?i=Ciona+intestinalis&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cg...i?i=Ciona+intestinalis&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Ciona+intestinalis&t=NS ... ...data Ciona_intestinalis_L.png Ciona_intestinalis_NL.png Ciona_intestinalis_S.png Ciona_intestinalis_NS.png h

  4. Taxonomy Icon Data: fruit fly [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available la_melanogaster_NL.png Drosophila_melanogaster_S.png Drosophila_melanogaster_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Drosophila+melanogaster&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Drosop...hila+melanogaster&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Drosophil...a+melanogaster&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Drosophila+melanogaster&t=NS ...

  5. Taxonomy Icon Data: sea urchin [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available rotus_lividus_NL.png Paracentrotus_lividus_S.png Paracentrotus_lividus_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Paracentrotus+lividus&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Paracentrotus+...lividus&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Paracentrotus+livid...us&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Paracentrotus+lividus&t=NS ...

  6. Taxonomy Icon Data: southern cassowary [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available _L.png Casuarius_casuarius_NL.png Casuarius_casuarius_S.png Casuarius_casuarius_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Casuarius+casuarius&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Casuari...us+casuarius&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Casuarius+casu...arius&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Casuarius+casuarius&t=NS ...

  7. Taxonomy Icon Data: maize [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available maize Zea mays Zea_mays_L.png Zea_mays_NL.png Zea_mays_S.png Zea_mays_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Zea+mays&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Zea...+mays&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Zea+mays&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Zea+mays&t=NS ...

  8. Taxonomy Icon Data: rainbow trout [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available ss_L.png Oncorhynchus_mykiss_NL.png Oncorhynchus_mykiss_S.png Oncorhynchus_mykiss_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Oncorhynchus+mykiss&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Oncor...hynchus+mykiss&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Oncorhynchus...+mykiss&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Oncorhynchus+mykiss&t=NS ...

  9. Taxonomy Icon Data: reindeer [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available a Rangifer_tarandus_L.png Rangifer_tarandus_NL.png Rangifer_tarandus_S.png Rangifer_tarandus_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Rangifer+tarandus&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cg...i?i=Rangifer+tarandus&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Rangi...fer+tarandus&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Rangifer+tarandus&t=NS ...

  10. Taxonomy Icon Data: wapiti [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available Cervus_canadensis_L.png Cervus_canadensis_NL.png Cervus_canadensis_S.png Cervus_canadensis_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Cervus+canadensis&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?...i=Cervus+canadensis&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Cervus+...canadensis&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Cervus+canadensis&t=NS ...

  11. Taxonomy Icon Data: Ciona savignyi (Sea squirt) [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available na_savignyi_L.png Ciona_savignyi_NL.png Ciona_savignyi_S.png Ciona_savignyi_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Ciona+savignyi&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Ciona+savignyi&t...=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Ciona+savignyi&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Ciona+savignyi&t=NS ...

  12. Taxonomy Icon Data: rat [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available egicus_L.png Rattus_norvegicus_NL.png Rattus_norvegicus_S.png Rattus_norvegicus_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Rattus+norvegicus&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Rattus+no...rvegicus&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Rattus+norvegicus&...t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Rattus+norvegicus&t=NS ...

  13. Taxonomy Icon Data: white shark [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available harias_L.png Carcharodon_carcharias_NL.png Carcharodon_carcharias_S.png Carcharodon_carcharias_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Carcharodon+carcharias&t=L http://biosciencedbc.jp/taxonomy_icon/...icon.cgi?i=Carcharodon+carcharias&t=NL http://biosciencedbc.jp/taxonomy_icon/icon....cgi?i=Carcharodon+carcharias&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Carcharodon+carcharias&t=NS ...

  14. Taxonomy Icon Data: wild radish [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available _NL.png Raphanus_raphanistrum_S.png Raphanus_raphanistrum_NS.png http://biosciencedbc.jp/taxonomy_icon/icon....cgi?i=Raphanus+raphanistrum&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Raphanus+raphanistrum&t=NL ...http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Raphanus+raphanistrum&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Raphanus+raphanistrum&t=NS ...

  15. Taxonomy Icon Data: Aardvark [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available opus_afer_L.png Orycteropus_afer_NL.png Orycteropus_afer_S.png Orycteropus_afer_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Orycteropus+afer&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Orycteropu...s+afer&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Orycteropus+afer&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Orycteropus+afer&t=NS ...

  16. Taxonomy Icon Data: ostrich [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available amelus_NL.png Struthio_camelus_S.png Struthio_camelus_NS.png http://biosciencedbc.jp/taxonomy_icon/icon.cgi?...i=Struthio+camelus&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Struthio+camelus&t=NL http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Struthio+camelus&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Struthio+camelus&t=NS ...

  17. Taxonomy Icon Data: wild goat [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available Capra_aegagrus_L.png Capra_aegagrus_NL.png Capra_aegagrus_S.png Capra_aegagrus_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Capra+aegagrus&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Capra+aegagru...s&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Capra+aegagrus&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Capra+aegagrus&t=NS ...

  18. Taxonomy Icon Data: llama [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available ma_L.png Lama_glama_NL.png Lama_glama_S.png Lama_glama_NS.png http://biosciencedbc.jp/taxonomy_icon/icon.cgi...?i=Lama+glama&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Lama+glama&t=NL http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Lama+glama&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Lama+glama&t=NS ...

  19. Taxonomy Icon Data: Australian lungfish [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available nomy_icon/icon.cgi?i=Neoceratodus+forsteri&t=L http://biosciencedbc.jp/taxonomy_ico...n/icon.cgi?i=Neoceratodus+forsteri&t=NL http://biosciencedbc.jp/taxonomy_icon/ico...n.cgi?i=Neoceratodus+forsteri&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Neoceratodus+forsteri&t=NS ... ...dus_forsteri_L.png Neoceratodus_forsteri_NL.png Neoceratodus_forsteri_S.png Neoceratodus_forsteri_NS.png http://biosciencedbc.jp/taxo

  20. Taxonomy Icon Data: brown bear [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available s_arctos_L.png Ursus_arctos_NL.png Ursus_arctos_S.png Ursus_arctos_NS.png http://biosciencedbc.jp/taxonomy_i...con/icon.cgi?i=Ursus+arctos&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Ursus+arctos&t=NL http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Ursus+arctos&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Ursus+arctos&t=NS ...

  1. Taxonomy Icon Data: Japanese skink [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available utatus_L.png Eumeces_latiscutatus_NL.png Eumeces_latiscutatus_S.png Eumeces_latiscutatus_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Eumeces+latiscutatus&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi...?i=Eumeces+latiscutatus&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Eum...eces+latiscutatus&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Eumeces+latiscutatus&t=NS ...

  2. Taxonomy Icon Data: Sympetrum frequens [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available _frequens_NL.png Sympetrum_frequens_S.png Sympetrum_frequens_NS.png http://biosciencedbc.jp/taxonomy_icon/ic...on.cgi?i=Sympetrum+frequens&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Sympetrum+frequens&t=NL http://biosciencedbc.jp/taxo...nomy_icon/icon.cgi?i=Sympetrum+frequens&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Sympetrum+frequens&t=NS ...

  3. Taxonomy Icon Data: turkey [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available gris_gallopavo_NL.png Meleagris_gallopavo_S.png Meleagris_gallopavo_NS.png http://biosciencedbc.jp/taxonomy_...icon/icon.cgi?i=Meleagris+gallopavo&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Meleagris+gallopavo...&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Meleagris+gallopavo&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Meleagris+gallopavo&t=NS ...

  4. Taxonomy Icon Data: pea aphid [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available sum_NL.png Acyrthosiphon_pisum_S.png Acyrthosiphon_pisum_NS.png http://biosciencedbc.jp/taxonomy_icon/icon.c...gi?i=Acyrthosiphon+pisum&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Acyrthosiphon+pisum&t=NL http://biosciencedbc.jp/taxono...my_icon/icon.cgi?i=Acyrthosiphon+pisum&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Acyrthosiphon+pisum&t=NS ...

  5. Taxonomy Icon Data: Southern elephant seal [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available onomy_icon/icon.cgi?i=Mirounga+leonina&t=L http://biosciencedbc.jp/taxonomy_icon/ic...on.cgi?i=Mirounga+leonina&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=M...irounga+leonina&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Mirounga+leonina&t=NS ... ...a/Carnivora Mirounga_leonina_L.png Mirounga_leonina_NL.png Mirounga_leonina_S.png Mirounga_leonina_NS.png http://biosciencedbc.jp/tax

  6. Taxonomy Icon Data: cape rock hyrax [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available Procavia_capensis_L.png Procavia_capensis_NL.png Procavia_capensis_S.png Procavia_capensis_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Procavia+capensis&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi...?i=Procavia+capensis&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Procav...ia+capensis&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Procavia+capensis&t=NS ...

  7. Taxonomy Icon Data: moose [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available lces_L.png Alces_alces_NL.png Alces_alces_S.png Alces_alces_NS.png http://biosciencedbc.jp/taxonomy_icon/ico...n.cgi?i=Alces+alces&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Alces+alces&t=NL http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Alces+alces&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Alces+alces&t=NS ...

  8. Taxonomy Icon Data: [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available nomy_icon/icon.cgi?i=Triceratops+horridus&t=L http://biosciencedbc.jp/taxonomy_icon.../icon.cgi?i=Triceratops+horridus&t=NL http://biosciencedbc.jp/taxonomy_icon/icon....cgi?i=Triceratops+horridus&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Triceratops+horridus&t=NS ... ...ratops_horridus_L.png Triceratops_horridus_NL.png Triceratops_horridus_S.png Triceratops_horridus_NS.png http://biosciencedbc.jp/taxo

  9. Taxonomy Icon Data: Striped bark scorpion [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available Centruroides_vittatus_NL.png Centruroides_vittatus_S.png Centruroides_vittatus_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Centruroides+vittatus&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Centru...roides+vittatus&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Centruroide...s+vittatus&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Centruroides+vittatus&t=NS ...

  10. Taxonomy Icon Data: emperor penguin [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available L.png Aptenodytes_forsteri_NL.png Aptenodytes_forsteri_S.png Aptenodytes_forsteri_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Aptenodytes+forsteri&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Apte...nodytes+forsteri&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Aptenodyte...s+forsteri&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Aptenodytes+forsteri&t=NS ...

  11. Taxonomy Icon Data: Japanese weasel [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available ra Mustela_itatsi_L.png Mustela_itatsi_NL.png Mustela_itatsi_S.png Mustela_itatsi_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Mustela+itatsi&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Mustela+it...atsi&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Mustela+itatsi&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Mustela+itatsi&t=NS ...

  12. Taxonomy Icon Data: Aegilops speltoides [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available es_NL.png Aegilops_speltoides_S.png Aegilops_speltoides_NS.png http://biosciencedbc.jp/taxonomy_icon/icon.cg...i?i=Aegilops+speltoides&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Aegilops+speltoides&t=NL http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Aegilops+speltoides&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Aegilops+speltoides&t=NS ...

  13. Taxonomy Icon Data: wild Bactrian camel [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available odactyla Camelus_ferus_L.png Camelus_ferus_NL.png Camelus_ferus_S.png Camelus_ferus_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Camelus+ferus&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Camelus+f...erus&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Camelus+ferus&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Camelus+ferus&t=NS ...

  14. Taxonomy Icon Data: pygmy chimpanzee [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available Pan_paniscus_L.png Pan_paniscus_NL.png Pan_paniscus_S.png Pan_paniscus_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Pan+paniscus&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Pan+paniscus&t=NL http://biosciencedbc.jp/taxono...my_icon/icon.cgi?i=Pan+paniscus&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Pan+paniscus&t=NS ...

  15. Taxonomy Icon Data: African malaria mosquito [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available eles_gambiae_NL.png Anopheles_gambiae_S.png Anopheles_gambiae_NS.png http://biosciencedbc.jp/taxonomy_icon/i...con.cgi?i=Anopheles+gambiae&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Anopheles+gambiae&t=NL http://biosciencedbc.jp/taxon...omy_icon/icon.cgi?i=Anopheles+gambiae&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Anopheles+gambiae&t=NS ...

  16. Taxonomy Icon Data: Atlantic salmon [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available _salar_NL.png Salmo_salar_S.png Salmo_salar_NS.png http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Salmo+sa...lar&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Salmo+salar&t=NL http://biosciencedbc.jp/taxonomy_i...con/icon.cgi?i=Salmo+salar&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Salmo+salar&t=NS ...

  17. Taxonomy Icon Data: Formosan subterranean termite [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available nus_L.png Coptotermes_formosanus_NL.png Coptotermes_formosanus_S.png Coptotermes_formosanus_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Coptotermes+formosanus&t=L http://biosciencedbc.jp/taxonomy_icon/ico...n.cgi?i=Coptotermes+formosanus&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cg...i?i=Coptotermes+formosanus&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Coptotermes+formosanus&t=NS ...

  18. Taxonomy Icon Data: Grey heron [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available _NL.png Ardea_cinerea_S.png Ardea_cinerea_NS.png http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Ardea+cine...rea&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Ardea+cinerea&t=NL http://biosciencedbc.jp/taxonomy..._icon/icon.cgi?i=Ardea+cinerea&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi...?i=Ardea+cinerea&t=NS http://togodb.biosciencedbc.jp/togodb/view/taxonomy_icon_comment_en?species_id=2 ...

  19. Taxonomy Icon Data: alpaca [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available gna_pacos_L.png Vicugna_pacos_NL.png Vicugna_pacos_S.png Vicugna_pacos_NS.png http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Vicugna+pacos&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Vicugna+pacos&t=NL http://biosciencedbc.jp/taxo...nomy_icon/icon.cgi?i=Vicugna+pacos&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Vicugna+pacos&t=NS ...

  20. Taxonomy Icon Data: dugong [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available L.png Dugong_dugon_NL.png Dugong_dugon_S.png Dugong_dugon_NS.png http://biosciencedbc.jp/taxonomy_icon/icon....cgi?i=Dugong+dugon&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Dugong+dugon&t=NL http://biosciencedbc.jp/taxonom...y_icon/icon.cgi?i=Dugong+dugon&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Dugong+dugon&t=NS ...

  1. Taxonomy Icon Data: phylum Xenoturbellida [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available phylum Xenoturbellida Xenoturbella bocki Xenoturbellida Xenoturbella_bocki_L.png Xenoturbell...a_bocki_NL.png Xenoturbella_bocki_S.png Xenoturbella_bocki_NS.png http://biosciencedbc.jp/taxonomy_...icon/icon.cgi?i=Xenoturbella+bocki&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Xenoturbella+bocki&t...=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Xenoturbella+bocki&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Xenoturbella+bocki&t=NS ...

  2. Testing for Structural Change by D-Methods in Switching Simultaneous Equations Models.

    Science.gov (United States)

    1982-02-01

    0 -- (W,’W) [1 + H(D-) (W-0) = (,)I nl - HCX (1-a)-( Cll.-GC21.)FCX(6-6)] where nlIV, the ith component of ni is Now what we will do is express (6-6...222 Nlarabi. Nol N., nba Approtlesrtlng thle Circalar Cocerege M4treal, Mourlos N.. 00orreeeondfe Rules end Path Function,’ 14 pp., Feb 1970, I A054 429

  3. Taxonomy Icon Data: sorghum [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available sorghum Sorghum bicolor Sorghum_bicolor_L.png Sorghum_bicolor_NL.png Sorghum_bicolor_S.png Sorghum_bicolor..._NS.png http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Sorghum+bicolor&t=L http://b...iosciencedbc.jp/taxonomy_icon/icon.cgi?i=Sorghum+bicolor&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Sorghum+bicolor...&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Sorghum+bicolor&t=NS ...

  4. Taxonomy Icon Data: Escherichia coli [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available Escherichia coli Escherichia coli Escherichia_coli_L.png Escherichia_coli_NL.png Escherichia..._coli_S.png Escherichia_coli_NS.png http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Escherichia+co...li&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Escherichia+coli&t=NL http://biosciencedbc.jp/taxono...my_icon/icon.cgi?i=Escherichia+coli&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Escherichia+coli&t=NS ...

  5. Heat pumps and the economy. Part 1. Primary energy consumption in houses; Warmtepompen en economie. Deel 1. Primair energiegebruik in woningen

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-09-01

    In a positioning paper of the NL Agency the economic perspective of heat pumps is outlined. In three parts the chapters of the paper are summarized. This first part focuses on primary energy consumption in Dutch houses [Dutch] In een positioning paper van het Agentschap NL wordt het economisch perspectief van warmtepompen belicht. In 3 delen wordt steeds 1 hoofdstuk uit deze paper samengevat. Dit eerste deel gaat in op primair energiegebruik in Nederlandse woningen.

  6. Taxonomy Icon Data: honey bee [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available honey bee Apis mellifera Arthropoda Apis_mellifera_L.png Apis_mellifera_NL.png Apis_mellife...ra_S.png Apis_mellifera_NS.png http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Apis+mellifera&t=L h...ttp://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Apis+mellifera&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Apis+mellife...ra&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Apis+mellifera&t=NS ...

  7. Induction of lipid oxidation by polyunsaturated fatty acids of marine origin in small intestine of mice fed a high-fat diet

    Czech Academy of Sciences Publication Activity Database

    van Schothorst, E. M.; Flachs, Pavel; Franssen-van Hal, N.; Kuda, Ondřej; Bunschoten, A.; Molthoff, J.; Vink, C.; Hooiveld, G. J.E.J.; Kopecký, Jan; Keijer, J.

    2009-01-01

    Roč. 110, č. 10 (2009), s. 1-11 ISSN 1471-2164 R&D Projects: GA MŠk(CZ) 1M0520 Grant - others:Nature management and food quality(NL) 8037173901; Dutch Ministry of Economic Affairs through the Innovation Oriented Research Program on Genomics(NL) IGE01016 Institutional research plan: CEZ:AV0Z50110509 Keywords : PUFA * small intestinal Subject RIV: FB - Endocrinology, Diabetology, Metabolism, Nutrition Impact factor: 3.759, year: 2009

  8. Multifunctional hardmask neutral layer for directed self-assembly (DSA) patterning

    Science.gov (United States)

    Guerrero, Douglas J.; Hockey, Mary Ann; Wang, Yubao; Calderas, Eric

    2013-03-01

    Micro-phase separation for directed self-assembly (DSA) can be executed successfully only when the substrate surface on which the block co-polymer (BCP) is coated has properties that are ideal for attraction to each polymer type. The neutral underlayer (NUL) is an essential and critical component in DSA feasibility. Properties conducive for BCP patterning are primarily dependent on "brush" or "crosslinked" random co-polymer underlayers. Most DSA flows also require a lithography step (reflection control) and pattern transfer schemes at the end of the patterning process. A novel multifunctional hardmask neutral layer (HM NL) was developed to provide reflection control, surface energy matching, and pattern transfer capabilities in a grapho-epitaxy DSA process flow. It was found that the ideal surface energy for the HM NL is in the range of 38-45 dyn/cm. The robustness of the HM NL against exposure to process solvents and developers was identified. Process characteristics of the BCP (thickness, bake time and temperature) on the HM NL were defined. Using the HM NL instead of three distinct layers - bottom anti-reflective coating (BARC) and neutral and hardmask layers - in DSA line-space pitch tripling and contact hole shrinking processes was demonstrated. Finally, the capability of the HM NL to transfer a pattern into a 100-nm spin-on carbon (SOC) layer was shown.

  9. Organization of the auditory brainstem in a lizard, Gekko gecko. I. Auditory nerve, cochlear nuclei, and superior olivary nuclei.

    Science.gov (United States)

    Tang, Yezhong; Christensen-Dalsgaard, Jakob; Carr, Catherine E

    2012-06-01

    We used tract tracing to reveal the connections of the auditory brainstem in the Tokay gecko (Gekko gecko). The auditory nerve has two divisions, a rostroventrally directed projection of mid- to high best-frequency fibers to the nucleus angularis (NA) and a more dorsal and caudal projection of low to middle best-frequency fibers that bifurcate to project to both the NA and the nucleus magnocellularis (NM). The projection to NM formed large somatic terminals and bouton terminals. NM projected bilaterally to the second-order nucleus laminaris (NL), such that the ipsilateral projection innervated the dorsal NL neuropil, whereas the contralateral projection crossed the midline and innervated the ventral dendrites of NL neurons. Neurons in NL were generally bitufted, with dorsoventrally oriented dendrites. NL projected to the contralateral torus semicircularis and to the contralateral ventral superior olive (SOv). NA projected to ipsilateral dorsal superior olive (SOd), sent a major projection to the contralateral SOv, and projected to torus semicircularis. The SOd projected to the contralateral SOv, which projected back to the ipsilateral NM, NL, and NA. These results suggest homologous patterns of auditory connections in lizards and archosaurs but also different processing of low- and high-frequency information in the brainstem. Copyright © 2011 Wiley Periodicals, Inc.

  10. The sequential hypothesis of sleep function. III. The structure of postacquisition sleep in learning and nonlearning rats.

    Science.gov (United States)

    Ambrosini, M V; Langella, M; Gironi Carnevale, U A; Giuditta, A

    1992-02-01

    EEG methods were used to examine the structure of postacquisition sleep in learning (L) and nonlearning (NL) rats previously exposed to a session of two-way active avoidance training, and in control rats (C) left in their home cages. In agreement with literature data, the number and total amount of paradoxical sleep (PS) episodes were higher in L rats than in NL rats. In addition, significant differences between L and NL rats concerned the episodes of synchronized sleep followed by wakefulness or by PS (SS-W and SS-PS, respectively). The average duration and related parameters of SS-W episodes, and the average duration, number, amount and related parameters of SS-PS episodes increased in NL and L rats in comparison with C rats. Longer SS-W episodes occurred early in NL and L rats, but the effect lasted longer in NL rats. On the other hand, the increments concerning SS-PS episodes occurred earlier, were more pronounced and laster longer in L rats. The results support a role of SS in brain information processing, as envisaged by the sequential hypothesis on the role of sleep. They suggest, furthermore, that memory traces lacking adaptive value may be destabilized and cleared away during SS-W and SS-PS episodes, while the remaining memory traces may be retained and eventually stored again in more integrated form during SS-PS and PS episodes, respectively.

  11. Measuring Gratitude: A Comparative Validation of the Dutch Gratitude Questionnaire (GQ6 and Short Gratitude, Resentment, and Appreciation Test (SGRAT

    Directory of Open Access Journals (Sweden)

    Lilian Jans-Beken

    2015-05-01

    Full Text Available The aim of this article was to validate and compare the Dutch translations of the Gratitude Questionnaire (GQ6 and the Short Gratitude, Resentment, and Appreciation Test (SGRAT in an adult general population sample. In an online survey, 706 respondents ('M 'age = 44, 'SD 'age = 14 completed Dutch versions of the GQ6, the SGRAT, the Satisfaction With Life Scale (SWLS and the Positive Affect and Negative Affect Schedule (PANAS. At six week follow-up, 440 (62% of them ('M' age = 46, 'SD' age = 14 again completed the GQ6-NL and SGRAT-NL. Parallel analyses, exploratory factor analyses and confirmatory factor analyses revealed and confirmed one factor for the GQ6-NL, and three factors for the SGRAT-NL. Internal consistency indices of the GQ6-NL and of the SGRAT-NL were satisfactory. Both questionnaires demonstrated good test-retest reliability. Regression analyses showed, for the total scores on both gratitude questionnaires, positive associations with the SWLS and the Positive Affect Scale, and negative associations with the Negative Affect Scale. The results support the validity of the Dutch GQ6 and SGRAT. These questionnaires can be used to conduct further research of the grateful disposition in Dutch speaking individuals and groups.

  12. Consistency relation for the Lorentz invariant single-field inflation

    International Nuclear Information System (INIS)

    Huang, Qing-Guo

    2010-01-01

    In this paper we compute the sizes of equilateral and orthogonal shape bispectrum for the general Lorentz invariant single-field inflation. The stability of field theory implies a non-negative square of sound speed which leads to a consistency relation between the sizes of orthogonal and equilateral shape bispectrum, namely f NL orth. ≤ −0.054f NL equil. . In particular, for the single-field Dirac-Born-Infeld (DBI) inflation, the consistency relation becomes f NL orth. = 0.070f NL equil. ≤ 0. These consistency relations are also valid in the mixed scenario where the quantum fluctuations of some other light scalar fields contribute to a part of total curvature perturbation on the super-horizon scale and may generate a local form bispectrum. A distinguishing prediction of the mixed scenario is τ NL loc. > ((6/5)f NL loc. ) 2 . Comparing these consistency relations to WMAP 7yr data, there is still a big room for the Lorentz invariant inflation, but DBI inflation has been disfavored at more than 68% CL

  13. STUDY OF VARIOUS MEASUREMENTS OF INTUBATION IN INFANTS AND THEIR CORRELATION WITH PREDICTION OF DIFFICULT INTUBATION

    Directory of Open Access Journals (Sweden)

    Seema

    2016-03-01

    Full Text Available BACKGROUND & AIMS Several pre-operative screening tools are used in adult. Wide range of pediatric anatomical & developmental differences (especially with infants makes uses of adult clinical predictors in challenge. The aim of our study is to assess various measurements of intubation in infants and their correlation with difficult laryngoscopy. MATERIAL AND METHODS This prospective randomized study conducted in 100 infants. We assessed the usefulness of neck length (NL, neck circumference (NC, Head Circumference, (HC ratio of NC/NL and introduced length of laryngoscope blade as predictors of difficult laryngoscopy and intubation. RESULT NC, NL, HC and ratio of NC/NL were significantly associated with incidence of difficult laryngoscopy and intubation. As this ratio increases difficulty at laryngoscopy increases (p<.001. Difficult laryngoscopy was assessed using Cormack Lehane grading. We found as age increases laryngoscopy becomes easier. (p<0.05 CONCLUSION There is no single anatomical measurement of intubation in infants in our study we measured NC, NL, NC/NL, HC and introduced length of laryngoscope blade which were found to be important predictors of difficult laryngoscopy and intubation. Statistical significant correlation was found between age and Cormack Lehane grades. In infants, various congenital malformations are highly associated with difficult laryngoscopy and intubation.

  14. Knockdown of TOR causing ovarian diapause in a genetically stable brachypterous strain of Nilaparvata lugens.

    Science.gov (United States)

    Liu, Fangzhou; Li, Kaiyin; Cai, Wanlun; Zhao, Jing; Zou, Yulan; Hua, Hongxia

    2017-08-01

    Brown planthopper (BPH), Nilaparvata lugens (Stål) (Hemiptera: Delphacidae), is one of the most damaging pests of rice crops. BPH is a migratory insect with a delayed ovarian development in migrants classified as reproductive diapause. The molecular mechanism of reproductive diapause remains unclear, although we suspect it might be regulated by one or more nutrient signaling pathways. The target of rapamycin (TOR) pathway regulates cell growth in response to nutritional information, which raised a hypothesis that TOR mediates BPH reproductive diapause. We used a pure brachypterous strain (BS) and a predominantly macropterous strain (MS) to investigate the roles of NlTOR in BPH reproductive diapause. We found that NlTOR is expressed from the nymphal to adult stages, with a higher expression level of NlTOR in BS adults at 1, 2, and 4 days posteclosion than in MS at the same time points. Injection of dsNlTOR into BS nymphs resulted in the termination of BPH female ovary development and the retardation of nymph development. We infer that TOR signaling functions in BPH reproductive diapause by regulating the expression of NlFoxA and NlVitellogenin. © 2017 Wiley Periodicals, Inc.

  15. Planck 2015 results. XVII. Constraints on primordial non-Gaussianity

    CERN Document Server

    Ade, P.A.R.; Arnaud, M.; Arroja, F.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Ballardini, M.; Banday, A.J.; Barreiro, R.B.; Bartolo, N.; Basak, S.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.P.; Bersanelli, M.; Bielewicz, P.; Bock, J.J.; Bonaldi, A.; Bonavera, L.; Bond, J.R.; Borrill, J.; Bouchet, F.R.; Boulanger, F.; Bucher, M.; Burigana, C.; Butler, R.C.; Calabrese, E.; Cardoso, J.F.; Catalano, A.; Challinor, A.; Chamballu, A.; Chiang, H.C.; Christensen, P.R.; Church, S.; Clements, D.L.; Colombi, S.; Colombo, L.P.L.; Combet, C.; Couchot, F.; Coulais, A.; Crill, B.P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R.D.; Davis, R.J.; de Bernardis, P.; De Rosa, A.; De Zotti, G.; Delabrouille, J.; Désert, F.X.; Diego, J.M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Enßlin, T.A.; Eriksen, H.K.; Fergusson, J.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A.A.; Franceschi, E.; Frejsel, A.; Galeotta, S.; Galli, S.; Ganga, K.; Gauthier, C.; Ghosh, T.; Giard, M.; Giraud-Héraud, Y.; Gjerløw, E.; González-Nuevo, J.; Górski, K.M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Gudmundsson, J.E.; Hamann, J.; Hansen, F.K.; Hanson, D.; Harrison, D.L.; Heavens, A.; Helou, G.; Henrot-Versillé, S.; Hernández-Monteagudo, C.; Herranz, D.; Hildebrandt, S.R.; Hivon, E.; Hobson, M.; Holmes, W.A.; Hornstrup, A.; Hovest, W.; Huang, Z.; Huffenberger, K.M.; Hurier, G.; Jaffe, A.H.; Jaffe, T.R.; Jones, W.C.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kim, J.; Kisner, T.S.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lacasa, F.; Lagache, G.; Lähteenmäki, A.; Lamarre, J.M.; Lasenby, A.; Lattanzi, M.; Lawrence, C.R.; Leonardi, R.; Lesgourgues, J.; Levrier, F.; Lewis, A.; Liguori, M.; Lilje, P.B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P.M.; Macías-Pérez, J.F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Marinucci, D.; Maris, M.; Martin, P.G.; Martínez-González, E.; Masi, S.; Matarrese, S.; McGehee, P.; Meinhold, P.R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Miville-Deschênes, M.A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Münchmeyer, M.; Munshi, D.; Murphy, J.A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C.B.; Nørgaard-Nielsen, H.U.; Noviello, F.; Novikov, D.; Novikov, I.; Oxborrow, C.A.; Paci, F.; Pagano, L.; Pajot, F.; Paoletti, D.; Pasian, F.; Patanchon, G.; Peiris, H.V.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Popa, L.; Pratt, G.W.; Prézeau, G.; Prunet, S.; Puget, J.L.; Rachen, J.P.; Racine, B.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Renzi, A.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Rossetti, M.; Roudier, G.; Rubiño-Martín, J.A.; Rusholme, B.; Sandri, M.; Santos, D.; Savelainen, M.; Savini, G.; Scott, D.; Seiffert, M.D.; Shellard, E.P.S.; Shiraishi, M.; Smith, K.; Spencer, L.D.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sunyaev, R.; Sutter, P.; Sutton, D.; Suur-Uski, A.S.; Sygnet, J.F.; Tauber, J.A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Troja, A.; Tucci, M.; Tuovinen, J.; Valenziano, L.; Valiviita, J.; van Tent, B.; Vielva, P.; Villa, F.; Wade, L.A.; Wandelt, B.D.; Wehus, I.K.; Yvon, D.; Zacchei, A.; Zonca, A.

    2016-01-01

    The Planck full mission cosmic microwave background(CMB) temperature and E-mode polarization maps are analysed to obtain constraints on primordial non-Gaussianity(NG). Using three classes of optimal bispectrum estimators - separable template-fitting (KSW), binned, and modal - we obtain consistent values for the local, equilateral, and orthogonal bispectrum amplitudes, quoting as our final result from temperature alone fNL^local=2.5+\\-5.7, fNL^equil=-16+\\-70 and fNL^ortho=-34+\\-33(68%CL). Combining temperature and polarization data we obtain fNL^local=0.8+\\-5.0, fNL^equil=-4+\\-43 and fNL^ortho=-26+\\-21 (68%CL). The results are based on cross-validation of these estimators on simulations, are stable across component separation techniques, pass an extensive suite of tests, and are consistent with Minkowski functionals based measurements. The effect of time-domain de-glitching systematics on the bispectrum is negligible. In spite of these test outcomes we conservatively label the results including polarization da...

  16. Nitrogen and phosphorus utilisation and excretion in dairy buffalo intensive breeding

    Directory of Open Access Journals (Sweden)

    Gianluca Neglia

    2014-10-01

    Full Text Available The aim of this study was to quantify nitrogen (N and phosphorus (P utilisation and excretion in intensive dairy buffaloes. Italian Mediterranean buffaloes were divided into 4 groups (n=6/group as follows: Groups M50, M125 and M225 at 50, 125 and 225 days of lactation, respectively, and Group NL which was non-lactating. Lactating buffaloes had greater (P<0.05 dry matter and organic matter intake than NL buffaloes. Buffaloes in Group M50 had a lower (P<0.05 crude protein (CP apparent digestibility than buffaloes in Groups M125 and M225. Group NL had a higher (P<0.01 real CP digestibility than Group M50. Buffaloes in Groups M50 and NL had a negative N balance (-79 and -12 g, respectively whilst buffaloes in Groups M125 and M225 had a positive N balance (26 and 16 g, respectively. Buffaloes in Group M50 had more (P<0.05 N in urine (204 g than Group NL (87 g. Buffaloes in Group NL had less (P<0.01 P in both faeces (12.9 g and urine (0.8 g compared with the three groups of lactating buffaloes combined (25 g in faeces and 12 g in urine and they also had greater (P<0.05 P digestibility (68% than lactating buffaloes combined (43%. The present study has shown that buffaloes have a relatively high efficiency of N and P utilisation.

  17. Ulcerated necrobiosis lipoidica to a teenager with diabetes mellitus and obesity.

    Science.gov (United States)

    Pătraşcu, Virgil; Giurcă, Claudia; Ciurea, Raluca Niculina; Georgescu, Corneliu Cristian; Ciurea, Marius Eugen

    2014-01-01

    Many skin lesions are associated with diabetes mellitus (DM) type 1 or 2, due to the use of antidiabetics or to metabolic and endocrine disorders caused by this disease. Necrobiosis lipoidica (NL) occurs more frequently in patients with DM. Painful ulcerations may occur on NL areas in about 20-25% of the cases and usually they are related to trauma. We present the case of a teenager, male, 17-year-old, having NL with multiple plaques, some of them spontaneously ulcerated after about 33 months of onset. He is known with type 1 DM from 2.5 years and the NL preceding the diagnosis of diabetes mellitus with about six months, presented erythematous-infiltrative skin plaques, some ulcerated for about three months, interesting both shins. Based on clinical, histopathological and paraclinical examinations, we established the following diagnoses: ulcerated NL, type 1 DM, moderate mixed dyslipidemia, class I obesity; commissural candidiasis, juvenile acne. Under treatment with Pentoxifyllinum, Sulodexidum, Ketotifenum and topical therapy with 0.2% Hyaluronic acid two months later, we have managed to heal two of the three ulcerated plaques and of the third has become superficial. We applied 0.5% Fluocortolonum on non-ulcerated plaques recording an improvement after two weeks of treatment. NL is a skin disease with a predilection for the shins, more frequent in patients with diabetes and is a part of palisading granulomatous dermatitis, which leads to skin atrophy. NL is found in the 0.3-1.2% of diabetic patients and is rare in children with diabetes (0.006%). It is more common in the patients with type 1 DM. The onset is in the third decade in diabetic patients and in the fourth decade in non-diabetics. There is no consensus concerning the treatment of NL, and the results are often modest. Antiplatelet agents, corticosteroids (local and general), immunomodulatory drugs, cyclins, wide synthetic antipaludics, heparin, Thalidomide are used. NL treatment is very difficult

  18. Excitation energies, radiative and autoionization rates, dielectronic satellite lines, and dielectronic recombination rates for excited states of Rb-like W from Kr-like W [Relativistic atomic data for Rb-like tungsten

    International Nuclear Information System (INIS)

    Safronova, University I.; Safronova, A. S.; Beiersdorfer, P.

    2016-01-01

    Energy levels, radiative transition probabilities, and autoionization rates for [Ni]4s 2 4p 6 nl, [Ni]4s 2 4p 5 4l ′ nl (l ′ =d,f,n = 4–7), [Ni]4s4p 6 4l ′ nl, (l ′ =d,f,n = 4–7), [Ni]4s 2 4p 5 5l ′ nl (n = 5–7), and [Ni]4s4p 6 6l ′ nl (n = 6–7) states in Rb-like tungsten (W37+) are calculated using the relativistic many-body perturbation theory method (RMBPT code) and the Hartree–Fock-relativistic method (COWAN code). Autoionizing levels above the [Ni]4s 2 4p 6 threshold are considered. It is found that configuration mixing among [Ni]4s 2 4p 5 4l ′ nl and [Ni]4s4p 6 4l ′ nl plays an important role for all atomic characteristics. Branching ratios relative to the first threshold and intensity factors are calculated for satellite lines, and dielectronic recombination (DR) rate coefficients are determined for the [Ni]4s 2 4p 6 nl (n = 4–7) singly excited states, as well as the [Ni]4s 2 4p 5 4dnl, [Ni]4s 2 4p 5 4fnl, [Ni]4s4p 6 4dnl, [Ni]4s 2 4p 6 4fnl, (n = 4–6), and [Ni]4s 2 4p 5 5l ′ 5l doubly excited nonautoionizing states in Rb-like W37+ ion. Contributions from the [Ni]4s24p 6 4fnl (n = 6–7), [Ni]4s 2 4p 5 5l ′ nl (n = 5–6), and [Ni]4s 2 4p 5 6l ′ nl (n = 6–7) doubly excited autoionizing states are evaluated numerically. The high-n state (with n up to 500) contributions are very important for high temperatures. These contributions are determined by using a scaling procedure. Synthetic dielectronic satellite spectra from Rb-like W are simulated in a broad spectral range from 8 to 70 Å. Here, these calculations provide highly accurate values for a number of W 37+ properties useful for a variety of applications including for fusion applications.

  19. Non-Lethal Sonodynamic Therapy Inhibits Atherosclerotic Plaque Progression in ApoE-/- Mice and Attenuates ox-LDL-mediated Macrophage Impairment by Inducing Heme Oxygenase-1

    Directory of Open Access Journals (Sweden)

    Yu Wang

    2017-05-01

    Full Text Available Background: Previous studies from our group showed that low-intensity sonodynamic therapy (SDT has protective effects on atherosclerosis (AS. However, because the intensity of ultrasound passing through tissue is attenuated, the consequences of very low-intensity SDT, referred to as non-lethal SDT (NL-SDT, on atherosclerotic plaques are unclear. The aim of this study was to determine whether NL-SDT affects atherosclerotic plaques and to elucidate the possible underlying mechanisms. Methods: An AS model was established using ApoE-/- mice fed a western diet. En face Oil Red O staining was used to measure atherosclerotic plaque size. Hematoxylin and eosin staining and immunohistochemical staining were used to observe plaque morphology and assess the location of macrophages and heme oxygenase 1 (HO-1. HO-1 mRNA and protein levels in AS plaques were evaluated by real-time PCR and western blotting. Human THP-1 cells and mouse peritoneal macrophages were used in this study. Western blotting was used to investigate the expression of cellular proteins after NL-SDT. Macrophage apoptosis was evaluated by TUNEL assays and flow cytometry with Annexin V/PI double staining. Intracellular reactive oxygen species (ROS and mitochondrial membrane potential (MMP were measured with 2′-7′-dichlorofluorescein diacetate (DCFH-DA and 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethyl benzimidazolyl carbocyanine iodide (JC-1 staining, respectively. Results: NL-SDT significantly inhibited AS progression and reduced the necrotic core area. NL-SDT induced HO-1 expression in lesional macrophages and in cultured macrophages. NL-SDT activated the protein kinase B (AKT and extracellular signal-related protein kinase (ERK pathways and the transcription factor NF-E2-related factor 2 (Nrf2.NL-SDT significantly reduced oxidized LDL (ox-LDL-induced macrophage MMP collapse, ROS production and cell apoptosis. Zinc protoporphyrin (ZnPP, a HO-1-specific inhibitor, reversed the

  20. Di-μ2-acetato-1:2κ2O:O′;2:3κ2O:O′-bis(N,N′-dimethylformamide-1κO,3κO-bis{μ2-2,2′-[propane-1,3-diylbis(iminomethylene]diphenolato-1κ4O,N,N′,O′:2κ2O,O′;2κ2O,O′:3κ4O,N,N′,O′-1,3-dinickel(II-2-cadmium(II

    Directory of Open Access Journals (Sweden)

    Orhan Atakol

    2008-02-01

    Full Text Available The crystal structure of the title compound, [Ni2Cd(C17H16N2O22(C2H3O22(C3H7NO2], contains discrete centrosymmetric hetero-trinuclear molecules in which Ni/Cd atom pairs are triply bridged via O atoms from the SALPD2− [N,N′-bis(salicylidene-1,3-propanediaminate] and acetate ligands. The central CdII ion is in a distorted octahedral coordination environment formed by four O atoms from two SALPD2− ligands in the equatorial plane and two O atoms of two symmetry-related acetate ligands in the axial positions. The symmetry-related NiII ions are in slightly distorted octahedral environments, coordinated by two O and two N atoms from tetradendate SALPD2− ligands in the equatorial plane, while the axial positions are occupied by O atoms from a dimethylformamide and an acetate ligand. This results in the formation of three edge-shared octahedra in which the Ni...Cd distance is 3.1482 (15 Å. The crystal structure is stabilized by weak C—H...O hydrogen bonds.