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Sample records for somali pirates kill

  1. PROSECUTING SOMALIA PIRATES AS TERRORISTS

    Directory of Open Access Journals (Sweden)

    ODHIAMBO E.O.S., ONKWARE K., KASSILLY J., NTABO O. M.

    2011-01-01

    Full Text Available This article starts from the assumption that piracy resembles terrorism in many aspects and attempts to support it through both a theoretical investigation and practical examples. The argument it makes is that Somali pirates should be prosecuted as terrorists. Moreover, it emphasizes the idea that for Somalia’s neighboring countries and not only the implementation of such an approach consists in resorting to the antiterrorist conventions already in place. Thus, for example, Kenya Navy as a piracyfi ghting agency should rely on these conventions to justify the capture and prosecution of pirates in Kenyan courts. In this respect, we emphasize the idea that only by resorting to an established international legal framework can Kenya identify the tools to counter pirates’ actions within legal limits. Moreover, this should be paralleled by efforts towards rebuilding Somalia and its institutions if long-term solutions are to be envisaged in the eradication of piracy in the Indian Ocean. In conclusion, the article looks at the concepts of piracy, terrorism and development in the Horn of Africa, suggests that piracy is a form of Terrorism and, makes a series of recommendations.

  2. Somalia’s ‘Pirate Cycle’

    DEFF Research Database (Denmark)

    Lucas, Edward

    2013-01-01

    -makers in the U.S. and elsewhere would be better able to judge when counter-piracy intervention is necessary. By preventing piracy from developing into large-scale professionalized operations, as witnessed in Somalia since 2007, the international community will be able carryout more efficient and effective piracy......This article provides a theoretical framework for examining Somali piracy from its origins in the 1990s to the present. This analysis provides both a detailed description of the changing nature of piracy, as well as explanations for why these changes have occurred. The increase in pirate activity...... off Somalia from 1991 to 2011 did not occur in a steady linear progression, but took place in three separate phases. These three phases can be viewed in terms of a “cycle of piracy,” based on a theory developed by the pirate historian Philip Gosse in 1932. By employing this framework, policy...

  3. "Robin Hook": The Developmental Effects of Somali Piracy

    OpenAIRE

    Shortland, Anja

    2011-01-01

    Copyright @ 2011 Brunel University Naval counter-piracy measures off Somalia have failed to change the incentives for pirates, raising calls for land-based approaches that may involve replacing piracy as a source of income. This paper evaluates the effects of piracy on the Somali economy to establish which (domestic) groups benefit from ransom monies. Given the paucity of economic data on Somalia, we evaluate province-level market data, nightlight emissions and high resolution satellite im...

  4. ‘War on piracy’: the conflation of Somali piracy with terrorism in discourse, tactic and law

    NARCIS (Netherlands)

    C. Singh (Currun); A.S. Bedi (Arjun Singh)

    2012-01-01

    textabstractThis paper argues that since 2005, the global security discourse has confused maritime piracy off the Horn of Africa with terrorism. American and European policymakers and financiers have tapped a vulnerable public imaginary to exaggerate Somali pirates as ‘maritime terrorists’ linked to

  5. Somalis in Europe

    OpenAIRE

    FAGIOLI-NDLOVU, Monica

    2015-01-01

    INTERACT - Researching Third Country Nationals? Integration as a Three-way Process - Immigrants, Countries of Emigration and Countries of Immigration as Actors of Integration Somalis have a long history in Europe; the first Somalis were seamen who arrived in the UK working on British ships at the beginning of the 20th century. Throughout different waves of migrations directly related to European colonial history, Somalis have settled down in various cities throughout Europe. More recently,...

  6. Teaching undergraduate astrophysics with PIRATE

    Science.gov (United States)

    Brodeur, M. S.; Kolb, U.; Minocha, S.; Braithwaite, N.

    2014-12-01

    PIRATE is a 0.43m semi-autonomous research and teaching observatory owned by The Open University, UK. Since 2010, it has been reserved for several months of each year for teaching astronomy in the OU's undergraduate programme. As students in these courses operate PIRATE remotely rather than travelling to the observatory itself, we chose to investigate whether effective learning was adversely affected by the absence of a more traditional `hands on' experience. We discuss student perspectives on the technologies employed (i.e., remote and virtual investigations), the impact these had on perceived course outcomes, and consider implications for future teaching and outreach.

  7. Somalis in Copenhagen

    DEFF Research Database (Denmark)

    Farah, Abdulkadir Osman

    , particularly a very high level of discrimination and stereotyping. The study reveals institutional gaps across different areas that need to be addressed urgently but also good practices at the local level.Somalis in Copenhagen is part of a comparative seven-city research series entitled Somalis in European...

  8. Literacy in Somali: Linguistic Consequences.

    Science.gov (United States)

    Biber, Douglas; Hared, Mohamed

    1991-01-01

    Linguistic consequences of literacy in Somalia are examined in a review of the literature and through a study of five dimensions of variation among Somali registers and the expansion of linguistic variation in Somali resulting from the introduction of written registers. (36 references) (LB)

  9. The Total Somali Clan Genealogy (second edition)

    NARCIS (Netherlands)

    Abbink, G.J.

    2009-01-01

    This paper presents an updated genealogy of all Somali 'clans'. Somali kinship is based on patrilineal descent or 'tol', but there are no equivalents in the Somali language for the words 'clan' and 'lineage'. The Somali terminology for the levels of social segmentation is complex, amongst others

  10. Health Information in Somali (Af-Soomaali )

    Science.gov (United States)

    ... and Wound Healing - Af-Soomaali (Somali) Bilingual PDF Health Information Translations Fasting Blood Sugar Test - Af-Soomaali (Somali) Bilingual PDF Health Information Translations GTT (Glucose Tolerance Test) - Af-Soomaali ( ...

  11. Somali Refugees' Perceptions of Mental Illness.

    Science.gov (United States)

    Bettmann, Joanna E; Penney, Deb; Clarkson Freeman, Pamela; Lecy, Natalie

    2015-01-01

    Nearly 13% of the U.S. population is comprised of foreign-born individuals, with Somalis constituting one of the largest resettled groups. Research suggests that, among Somali refugees, rates of mental illness are high. Yet research shows Somalis underutilize mental health services. Understanding their perceptions of mental illness and its cures may help practitioners to design more effective treatments for this population. Thus, this pilot study investigated Somali refugees' perceptions of mental illness and its treatments. Using purposive sampling, this qualitative study interviewed 20 Somali refugees using a semi-structured interview guide. Qualitative analysis yielded participants' perceptions of mental illness through their descriptions of physical symptoms accompanying mental illness, the stigma of mental illness, causes of mental illness, medical and non-medical treatments for mental illness, spirit possession causing mental illness, and the Qur'an as treatment for mental illness. Such information may help practitioners in the United States approach Somali clients in the most culturally coherent manner.

  12. The total Somali clan genealogy : a preliminary sketch

    NARCIS (Netherlands)

    Abbink, J.

    1999-01-01

    This paper presents a preliminary genealogy of all Somali 'clans'. Somali kinship is based on patrilineal descent, but there are no equivalents in the Somali language for the words 'clan' and 'lineage'. The Somali terminology for the levels of social segmentation is complex, amongst others because

  13. Pirate philosophy for a digital posthumanities

    CERN Document Server

    Hall, Gary

    2016-01-01

    In Pirate Philosophy, Gary Hall considers whether the fight against the neoliberal corporatization of higher education in fact requires scholars to transform their own lives and labor. Is there a way for philosophers and theorists to act not just for or with the antiausterity and student protestors—“graduates without a future”—but in terms of their political struggles? Drawing on such phenomena as peer-to-peer file sharing and anticopyright/pro-piracy movements, Hall explores how those in academia can move beyond finding new ways of thinking about the world to find instead new ways of being theorists and philosophers in the world. Hall describes the politics of online sharing, the battles against the current intellectual property regime, and the actions of Anonymous, LulzSec, Aaron Swartz, and others, and he explains Creative Commons and the open access, open source, and free software movements. But in the heart of the book he considers how, when it comes to scholarly ways of creating, performing, an...

  14. Cigarettes and the Somali diaspora: tobacco use among Somali adults in Minnesota.

    Science.gov (United States)

    Giuliani, Kristin K W; Mire, Osman; Leinberger-Jabari, Andrea; Ehrlich, Laura C; Stigler, Melissa H; Pryce, Douglas J; DuBois, Diana K

    2012-11-01

    Since the onset of the Somali civil war in 1991, more than 1 million Somalis have been displaced from Somalia. Minnesota has the largest Somali population in the U.S. Informal tobacco prevalence estimates among Somali populations in the U.S. and the United Kingdom range from 13% to 37%, respectively. Little research has been conducted to determine the extent of Somali tobacco use. This paper reports the results from a knowledge, attitudes, and practices (KAP) survey conducted and analyzed in 2009 that explores tobacco use and estimates prevalence among Somali adults aged ≥ 18 years in Minnesota. Modeled after validated state and national tobacco use surveys, the survey was adapted for Somalis and administered to ethnically Somali adults (N=392) from 25 neighborhood clusters in Minnesota. Participants were chosen through probability proportional to size and multistage random sampling methods. Estimated prevalence for cigarette use among Somalis was 24% (44% among men, 4% among women). Ever users were significantly more likely to be men, have attended college, and have friends who used cigarettes (pIslamic prohibition of tobacco was protective and affected current use and future intention to use tobacco (peducation levels. Positive peer pressure and religion are protective factors from tobacco use and should be integrated into prevention and cessation programs. Copyright © 2012 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  15. Pirate Alterity and Mimesis in Colonial Epic Poetry

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    Javier de Navascués

    2016-05-01

    Full Text Available Pirate representation is studied in a series of Epic poems in the late sixteenth century and early seventeenth century. The ambiguous image of the English enemy is read in texts by Juan de Miramontes, Pedro de Oña, Martín del Barco Centenera and Juan de Castellanos, among others. On the one hand, Colonial Epic ignores some important differences between privateers and pirates since the privateering had been legally accepted by all European nations, including Spain. Besides, Pirate is always called «Lutheran» and revealing its absolute otherness with respect to the Catholic model. On the other hand, it proposes a laudatory epics enemy painting from the imitation of the values accepted by the colonial society. The relationship between the Spanish hero and the privateer is represented not in a vertical direction, as could happen between colonizer and colonized subject, but on a level of rivalry.

  16. Somalis

    DEFF Research Database (Denmark)

    Farah, Abdulkadir Osman

    Contemporary scholarship characterizes Somalia as a nation in search of statehood. The approach presupposes a homogenous cohesive nation and society- with considerable traditional democratic pastoralism. This book portrays a complex nation with multiple heterogeneous characteristics. This alterna...

  17. Video Film Piracy in Nigeria: Interfacing to Integrate the Pirate ...

    African Journals Online (AJOL)

    It recommends the adoption of market segmentation policy in integrating the pirate, emphasises the run of video films in cinemas, halls etc before they go into the market and calls for a better synergy between producers and marketers among others. Key words: Identification, Interface, Integration, Market Segmentation ...

  18. Piratõ Karibskogo morja obideli tuzemtsev / Jekaterina Zhivova

    Index Scriptorium Estoniae

    Zhivova, Jekaterina

    2006-01-01

    Gore Verbinski lavastatud piraadi-triloogia teine film "Kariibi mere piraadid : Surnud mehe aardekirst" ("Pirates of the Caribbean : Dead Man's Chest") : Ameerika Ühendriigid 2006. Ülevaatlikult ka esimese filmiga seonduvast. Augustis lõppevad kolmanda filmi võtted

  19. Pirates, ports, and coasts in Asia: historical and contemporary perspectives

    NARCIS (Netherlands)

    Kleinen, J.; Osseweijer, M.

    2010-01-01

    Pirates, Ports and Coasts in Asia aims to fill in some of the historical gaps in the coverage of maritime piracy and armed robbery in Asia. The authors highlight a variety of activities ranging from raiding, destroying and pillaging coastal villages and capturing inhabitants to attacking and taking

  20. Pirated Siderophores Promote Sporulation in Bacillus subtilis.

    Science.gov (United States)

    Grandchamp, Gabrielle M; Caro, Lews; Shank, Elizabeth A

    2017-05-15

    In microbial communities, bacteria chemically and physically interact with one another. Some of these interactions are mediated by secreted specialized metabolites that act as either intraspecies or interspecies signals to alter gene expression and to change cell physiology. Bacillus subtilis is a well-characterized soil microbe that can differentiate into multiple cell types, including metabolically dormant endospores. We were interested in identifying microbial interactions that affected sporulation in B. subtilis Using a fluorescent transcriptional reporter, we observed that coculturing B. subtilis with Escherichia coli promoted sporulation gene expression via a secreted metabolite. To identify the active compound, we screened the E. coli Keio Collection and identified the sporulation-accelerating cue as the siderophore enterobactin. B. subtilis has multiple iron acquisition systems that are used to take up the B. subtilis- produced siderophore bacillibactin, as well as to pirate exogenous siderophores such as enterobactin. While B. subtilis uses a single substrate binding protein (FeuA) to take up both bacillibactin and enterobactin, we discovered that it requires two distinct genes to sporulate in response to these siderophores (the esterase gene besA for bacillibactin and a putative esterase gene, ybbA , for enterobactin). In addition, we found that siderophores from a variety of other microbial species also promote sporulation in B. subtilis Our results thus demonstrate that siderophores can act not only as bacterial iron acquisition systems but also as interspecies cues that alter cellular development and accelerate sporulation in B. subtilis IMPORTANCE While much is known about the genetic regulation of Bacillus subtilis sporulation, little is understood about how other bacteria influence this process. This work describes an interaction between Escherichia coli and B. subtilis that accelerates sporulation in B. subtilis The interaction is mediated by the E

  1. Clan and Islamic Identities in Somali Society

    Science.gov (United States)

    2011-11-01

    les déductions les plus intéressantes, y compris des comparaisons avec les histoires de la Pologne et de l’Ingouchie. Malgré la richesse de ces...Christian (1999). Le sang et le lait: Brève histoire des clans somali. Paris: Maisonneuve et Larose. [22] Bakonyi, Jutta (2009). Moral economies of...Uluslararasi Hukuk ve Politika, 6:24, 115-143. [67] Diriye Abdullahi, Mohamed (2000). Le Somali: Dialectes et histoire . Unpublished PhD

  2. Pirate political parties: New democracy or political utopia

    Directory of Open Access Journals (Sweden)

    Karanović Bojana

    2012-01-01

    Full Text Available Modern society is changing under the influence of IT technologies, more and more we talk about 'digital revolution', and political and economic developments are shaped by computer networks. Undeniably, the Internet has opened new possibilities for socio-political expansion, networking and mobilization. Besides the political establishment, many social movements found their chance in cyberspace recognizing the IT technology as a platform for the development and improvement of their internal and external communication. In this article we will focus on the Pirate Party, movement that has been seriously growing on the European political stage for last several years. Following the example of German Pirate Party we will try to explain the characteristics of the movement, its goals and communication strategies, and political dilemmas which it brings.

  3. Movie Pirates of the Caribbean: Exploring Illegal Streaming Cyberlockers

    OpenAIRE

    Ibosiola, Damilola; Steer, Benjamin; Garcia-Recuero, Alvaro; Stringhini, Gianluca; Uhlig, Steve; Tyson, Gareth

    2018-01-01

    Online video piracy (OVP) is a contentious topic, with strong proponents on both sides of the argument. Recently, a number of illegal websites, called streaming cyberlockers, have begun to dominate OVP. These websites specialise in distributing pirated content, underpinned by third party indexing services offering easy-to-access directories of content. This paper performs the first exploration of this new ecosystem. It characterises the content, as well the streaming cyberlockers' individual ...

  4. Piracy in cyber space: consumer complicity, pirates and enterprise enforcement

    Science.gov (United States)

    Chaudhry, Peggy E.; Chaudhry, Sohail S.; Stumpf, Stephen A.; Sudler, Hasshi

    2011-05-01

    This article presents an overview of the growth of internet piracy in the global marketplace. The ethical perceptions (or lack of) of the younger generation is addressed, in terms of their willingness to consume counterfeit goods on the web. Firms face the task of educating the consumer that downloading music, software, movies and the like, without compensation, is unethical. This awareness is critical for decreasing the demand for counterfeit goods in the virtual marketplace, where a consumer can exhibit a rogue behaviour with a limited fear of prosecution. We address the pyramid of internet piracy, which encompasses sophisticated suppliers/facilitators, such as the Warez group. Recent sting operations, such as Operation Buccaneer, are also depicted to highlight successful tactical manoeuvres of enforcement agencies. An overview of the Digital Millennium Copyright Act and the No Electronic Theft Act is included to debate the controversy surrounding this legislation. A discussion of enterprise enforcement mechanisms and novel anti-piracy technology for cyberspace is provided to reveal some of the tools used to fight the pirates, such as innovations in digital watermarking and NEC's recently announced video content identification technology. Enterprise information systems and its interdependence on the internet are also demanding new technologies that enable internet investigators to rapidly search, verify and potentially remove pirated content using web services. The quality of service of web services designed to efficiently detect pirated content is a growing consideration for new anti-piracy technology.

  5. Piratería nabatea en el Mar Rojo

    Directory of Open Access Journals (Sweden)

    Carmen Blánquez Pérez

    2011-01-01

    Full Text Available Las actividades marítimas de los nabateos han sido poco estudiadas, a pesar de que aparecen mencionadas en las fuentes antiguas. En el presente artículo se revisan las distintas hipótesis planteadas por los historiadores actuales, que se centran en el declive del comercio nabateo y en el descubrimiento de los monzones. Sin embargo, no existió un declive comercial que justificara las actividades de piratería de los nabateos, y el descubrimiento de los monzones no se corresponde con el período en que dichas actividades de piratería tuvieron lugar.Maritime activities of the Nabataeans are poorly understood, although are mentioned in ancient sources. In this article we review the various hypotheses raised by modern historians, who focus on the Nabatean trade decline and the discovery of the monsoons. However, there was no declining sales to justify piracy activities of the Nabataeans, and the discovery of the monsoon does not correspond to the period in which these pirate activities took place.

  6. In-theater piracy: finding where the pirate was

    Science.gov (United States)

    Chupeau, Bertrand; Massoudi, Ayoub; Lefèbvre, Frédéric

    2008-02-01

    Pirate copies of feature films are proliferating on the Internet. DVD rip or screener recording methods involve the duplication of officially distributed media whereas 'cam' versions are illicitly captured with handheld camcorders in movie theaters. Several, complementary, multimedia forensic techniques such as copy identification, forensic tracking marks or sensor forensics can deter those clandestine recordings. In the case of camcorder capture in a theater, the image is often geometrically distorted, the main artifact being the trapezoidal effect, also known as 'keystoning', due to a capture viewing axis not being perpendicular to the screen. In this paper we propose to analyze the geometric distortions in a pirate copy to determine the camcorder viewing angle to the screen perpendicular and derive the approximate position of the pirate in the theater. The problem is first of all geometrically defined, by describing the general projection and capture setup, and by identifying unknown parameters and estimates. The estimation approach based on the identification of an eight-parameter homographic model of the 'keystoning' effect is then presented. A validation experiment based on ground truth collected in a real movie theater is reported, and the accuracy of the proposed method is assessed.

  7. Somali Pirates: A New Phase Zero Stability Operational Approach, a Strategic Imperative in the Horn of Africa

    Science.gov (United States)

    2010-06-18

    Colorado. The Larson’s have two children Andrew 12, and Ava 9. They reside in Virginia Beach where they enjoy water sports, soccer, and equine ...building strategy. The understanding and complexity of the problem unfolds with the knowledge that previous security sector reform efforts in Somalia may...at security sector reform,” Abdi observers, “have seen money disappear into a black hole as there was no accountability.൱ It appears that both

  8. Emergency within an emergency: Somali IDP s

    Directory of Open Access Journals (Sweden)

    Hassan Noor

    2007-07-01

    Full Text Available International media report that over 300,000 Somalis have been newly displaced by fighting in Mogadishu. Conflict-related displacement hits the headlines but the numbers displaced by environmental change are also colossal. The international response remains woefully inadequate.

  9. 77 FR 31493 - Eighth Coast Guard District Annual Marine Events and Safety Zones; Billy Bowlegs Pirate Festival...

    Science.gov (United States)

    2012-05-29

    ... Bowlegs Pirate Festival; Santa Rosa Sound; Ft. Walton Beach, FL AGENCY: Coast Guard, DHS. ACTION: Notice... Safety Zone for the Billy Bowlegs Pirate Festival in the Santa Rosa Sound, Ft. Walton Beach, FL on June 1... crews, vessels, and persons on navigable waters during the Billy Bowlegs Pirate Festival. During the...

  10. Piracy Versus Privacy: An Analysis of Values Encoded in the PirateBrowser

    NARCIS (Netherlands)

    Bodó, B.

    2015-01-01

    The Piratebrowser is a web browser which utilizes the Privacy Enhancing Technology Tor to circumvent nationally implemented internet filters blocking the access to the Pirate Bay. The article analyzes the possible consequences of a mass influx of copyright pirates into the privacy domain. It

  11. Pirates of the Philippines: A Critical Thinking Exercise

    Directory of Open Access Journals (Sweden)

    Ruel A. Macaraeg

    2012-07-01

    Full Text Available Piracy had a formative impact on Filipino history, yet modern practitioners of Filipino Martial Arts generally do not acknowledge its influence. This brief study reconstructs the pirates’ martial practices through comparative historical analysis of their weapons, costume, and organization in order to draw conclusions about their relationship to martial cultures in the Philippines and across the region. Using analogous historical studies on piracy worldwide and examination of traditional arms and armor, this article restores the Iranun pirates to their rightful place as primary contributors to Filipino fighting arts and their influence in shaping Filipino national historiography as a whole.

  12. Postpartum Depression Among Somali Women in Norway.

    Science.gov (United States)

    Løvlie, Astrid Louise; Madar, Ahmed Ali

    2017-06-01

    Postpartum depression (PPD) has been described as the most common complication experienced postpartum, affecting about 10-15 % of all new mothers. Factors like a history of mental illness, and experienced recent adverse life events has been associated with an increased risk for developing PPD. Immigrant women in Western countries have been found to have a marked higher prevalence of PPD compared to the general population. In Norway the prevalence of PPD in the general population has been found to be around 8-10 %, and among Pakistani immigrants a rate of 7.6 % was found. Somali people in Norway are the second largest immigrant group in Norway with a non-Western background. No study on PPD and associated factors among Somali women has been found in the literature. The aim of the study was to assess PPD and associated factors among Somali women in greater Oslo region, Norway. A cross-sectional survey was conducted; recruiting new mothers through all maternity wards in the Oslo region. Data was collected with interview-administrated questionnaires. PPD was assessed using Edinburgh Postnatal Depression Scale (EPDS), defining those scoring ≥10 to have a possible PPD. Of the 80 eligible women identified, 39 (49 %) consented to participate, and completed the study. Of the 39 respondents 3 (7.7 %) were assessed to have a possible PPD. Most important associated factors found were history of mental illness, having experienced technical assistance during delivery, self-rated health and experienced economical problems last 12 months. A low prevalence of PPD was found, and both the prevalence and its associated factors should be interpreted with caution. The associated factors do not have enough power to give any strength to the associations. However, some of the results can be used in develop new hypotheses with regard to PPD among Somali women as immigrants in a Western society.

  13. The Killing

    DEFF Research Database (Denmark)

    Agger, Gunhild

    2013-01-01

    This article tracks the uncanny locations of The Killing (2007–2012), relating them to place, space and atmosphere, putting bits and pieces from the topographic puzzle together with cues from the symbolic space in order to see how they fit into the overall pattern of Nordic Noir. In The Killing......, the abstract level of space and atmosphere meets the concrete level of place, both influencing the notion of location. This meeting, I suggest, has contributed towards the simultaneous domestic and international appeal of The Killing....

  14. Associations for Disruptiveness: The Pirate Bay vs. Spotify

    Directory of Open Access Journals (Sweden)

    Bjorn Remneland Wikhamn

    2016-10-01

    Full Text Available Most studies on disruptive innovations adopt technology-centric assumptions when explaining how industries are affected by a technology’s creative destruction. This paper argues that the power of a technology lies in how it performatively associates with the cultural and social norms of the wider society. Hence, a technology is not disruptive or sustaining in itself but is potentially a productive outcome of network linkages with other social and material elements. To illustrate this claim, two digital music services will be analyzed, respectively a misfit and a maverick both challenging mainstream providers of music – The Pirate Bay and Spotify – in relation to each other and how they are positioned toward the transformation of the music industry as a whole.

  15. OK, Computer: File Sharing, the Music Industry, and Why We Need the Pirate Party

    Directory of Open Access Journals (Sweden)

    Adrian Cosstick

    2009-03-01

    Full Text Available The Pirate Party believes the state and big business are in the process of protecting stale and inefficient models of business for their own monetary benefit by limiting our right to share information. The Pirate Party suggests that they are achieving this goal through the amendment of intellectual property legislation. In the dawn of the digital era, the Pirate Party advocates that governments and multinational corporations are using intellectual property to: crack down on file sharing which limits the ability to share knowledge and information; increase the terms and length of copyright to raise profits; and build code into music files which limits their ability to be shared (Pirate Party, 2009. There are a number of ‘copyright industries’ that are affected by these issues, none more so than the music industry. Its relationship with file sharing is topical and makes an excellent case study to address the impact big business has had on intellectual property and the need for the Pirate Party’s legislative input. The essay will then examine the central issues raised by illegal file sharing. In particular, the future for record companies in an environment that increasingly demands flexibility, and whether the Pirate Party’s proposal is a viable solution to the music industry’s problems

  16. Killing Range

    Science.gov (United States)

    Asal, Victor; Rethemeyer, R. Karl; Horgan, John

    2015-01-01

    This paper presents an analysis of the Provisional Irish Republican Army's (PIRA) brigade level behavior during the Northern Ireland Conflict (1970-1998) and identifies the organizational factors that impact a brigade's lethality as measured via terrorist attacks. Key independent variables include levels of technical expertise, cadre age, counter-terrorism policies experienced, brigade size, and IED components and delivery methods. We find that technical expertise within a brigade allows for careful IED usage, which significantly minimizes civilian casualties (a specific strategic goal of PIRA) while increasing the ability to kill more high value targets with IEDs. Lethal counter-terrorism events also significantly affect a brigade's likelihood of killing both civilians and high-value targets but in different ways. Killing PIRA members significantly decreases IED fatalities but also significantly decreases the possibility of zero civilian IED-related deaths in a given year. Killing innocent Catholics in a Brigade's county significantly increases total and civilian IED fatalities. Together the results suggest the necessity to analyze dynamic situational variables that impact terrorist group behavior at the sub-unit level. PMID:25838603

  17. The Roots and Routes of Somali Transnational Clan Formations

    DEFF Research Database (Denmark)

    Farah, Abdulkadir Osman

    2017-01-01

    In normal circumstances clan represents a real or imagined lineage people claim to belong. Among the Somalis such relations remain largely patriarchal. Clans also have both exclusionary and inclusionary mechanism to expand and restrict power relations in the community and in the society. The social...... and cultural rules and norms that govern such relationship depend on the context as well as the surrounding socio-political and cultural conditions. Due to the fragmentation of the Somali society since 1991 most Somalis are directly or indirectly linked to a clan for diverse motives- including the need...

  18. Killing tensors and conformal Killing tensors from conformal Killing vectors

    International Nuclear Information System (INIS)

    Rani, Raffaele; Edgar, S Brian; Barnes, Alan

    2003-01-01

    Koutras has proposed some methods to construct reducible proper conformal Killing tensors and Killing tensors (which are, in general, irreducible) when a pair of orthogonal conformal Killing vectors exist in a given space. We give the completely general result demonstrating that this severe restriction of orthogonality is unnecessary. In addition, we correct and extend some results concerning Killing tensors constructed from a single conformal Killing vector. A number of examples demonstrate that it is possible to construct a much larger class of reducible proper conformal Killing tensors and Killing tensors than permitted by the Koutras algorithms. In particular, by showing that all conformal Killing tensors are reducible in conformally flat spaces, we have a method of constructing all conformal Killing tensors, and hence all the Killing tensors (which will in general be irreducible) of conformally flat spaces using their conformal Killing vectors

  19. Afghan and Somali (post-conflict migration to the EU

    Directory of Open Access Journals (Sweden)

    Nassim Majidi

    2016-01-01

    Full Text Available There are invisible drivers of migration for Afghans and Somalis to Europe, caused by decades of conflict. Although officially considered as ‘postconflict’, the reality is very different.

  20. Barriers to outdoor physical activity in wintertime among Somali youth.

    Science.gov (United States)

    Rothe, Elizabeth; Holt, Christina; Kuhn, Celine; McAteer, Timothy; Askari, Isabella; O'Meara, Mary; Sharif, Abdimajid; Dexter, William

    2010-10-01

    To identify barriers to outdoor physical activity in winter among Somali youth in Maine. Despite the many proven health benefits of physical activity among children, such as cardiovascular fitness and health status as an adult, there has been a decrease in physical activity among children in recent years. Specifically, children who are of low socio-economic status or are from communities where many immigrants are at increased risk for developing obesity. Immigrants are also less likely to be physically active. There are many potential barriers to wintertime physical activity among Somali youth in Maine, such as lack of financial resources, transportation, proper winter clothing, and appropriate knowledge of winter safety, and language and cultural barriers. For females, different attire required for outdoor activity may be a barrier. Somali parents and children were recruited from Portland, Maine to participate in focus groups led by a trained facilitator with a Somali translator and cultural broker. Transcripts were coded using NVIVO software to identify barriers to physical activity among Somali youth outside in winter. Eight focus groups were conducted. Sixty-one Somali community members were recruited. Participants felt outdoor physical activity is important, but note that it is decreased in winter. Barriers to outdoor activity in winter cited by focus group participants were lack of resources, health concerns, gender barriers for females, and knowledge barriers. Concern over lack of supervision while children play outside was also cited. This study revealed many of the underlying beliefs, barriers and cultural issues that impact Somali families' intention to be active and ability to be active outdoors in winter. These findings can be used to generate research hypotheses and public health interventions regarding outdoor physical activity among Somali youth.

  1. The EU Comprehensive Approach on Somali Piracy

    Directory of Open Access Journals (Sweden)

    Angela Caramerli

    2015-07-01

    Full Text Available The Gulf of Aden represents a strategic issue for the international community, as its geographical position is fundamental as the major trade maritime route. About 50 percent of the world container ships pass through the Gulf of Aden each year, 80 percent of those cargos coming from Europe. For this reason, the piracy issue affecting Somalia is a problem affecting EU member states’ security and economy. This paper is focused on the comprehensive approach acted by the European Union, with a special attention on proposing the implementation of programs against illegal fishing and waste dumping in order to fight Somali piracy. The evaluation of the military mission offers an overview on a solution for the near future, while the training missions and the development funds sustain the build-up of national tools and focus on the solving of the roots of the issue.

  2. Need for industry to adopt a proactive role against pirates

    Science.gov (United States)

    Heslop, Jack

    1990-04-01

    How many times has a friend-usually recently returned from a trip to the Far East- shown you the fake Rolex or Cartier wrist-watch purchased for little more than the cost of a meal? If honest, I think our usual reaction is one of: "What a bargain, wish you had bought one for me!" Now imagine you are Sitting in the airliner flying at 10,000 metres, and the passenger sitting next to you reveals that he has just sold fake brake pads or fake wing bolts to the purchasing department of that particular airline. Sounds far fetched - doesn't it? However, in this day and age, such a proposition is perfectly feasible and later I will quote examples of fake products which, quite literally, will make your hair stand on end! Whilst it is always difficult to obtain accurate figures as to the extent of the global trade in counterfeit products, it is conservatively estimated to account for some 5% of world trade, or around $100 billion U.S. per year. Unfortunately, all the indications are that the problem is growing. Today, with all the advances of modern technology, it is all too easy for the Pirate to copy those goods regarded as the "brand leaders" in any particular industry.

  3. Factors Related to Motivating Adult Somalis with Refugee Status to Volunteer for 4-H

    Science.gov (United States)

    Mason, Mitchell D.; Ouellette, Kristy L.

    2016-01-01

    Focus group interviews were held with adult Somali immigrants to assess their likelihood of volunteering for 4-H in Maine. This qualitative study was undertaken to identify best practices for engaging the growing Somali-Mainer population as a volunteer base. Results of the study demonstrate that Somali immigrant adults are willing to volunteer for…

  4. Providers' Perceptions of Challenges in Obstetrical Care for Somali Women

    Directory of Open Access Journals (Sweden)

    Jalana N. Lazar

    2013-01-01

    Full Text Available Background. This pilot study explored health care providers’ perceptions of barriers to providing health care services to Somali refugee women. The specific aim was to obtain information about providers’ experiences, training, practices and attitudes surrounding the prenatal care, delivery, and management of women with Female Genital Cutting (FGC. Methods. Individual semi-structured interviews were conducted with 14 obstetricians/gynecologists and nurse midwives in Columbus, Ohio. Results. While providers did not perceive FGC as a significant barrier in itself, they noted considerable challenges in communicating with their Somali patients and the lack of formal training or protocols guiding the management of circumcised women. Providers expressed frustration with what they perceived as Somali patients' resistance to obstetrical interventions and disappointment with a perception of mistrust from patients and their families. Conclusion. Improving the clinical encounter for both patients and providers entails establishing effective dialogue, enhancing clinical and cultural training of providers, improving health literacy, and developing trust through community engagement.

  5. Mark Twain, Walt Disney, and the Playful Response to Pirate Stories

    Science.gov (United States)

    West, Mark I.

    2010-01-01

    Like many a modern play theorist, both Mark Twain and Walt Disney were enchanted by the way children act out stories, in particular pirate tales. For both Twain and Disney, this fascination grew out of their small-town, midwestern boyhoods, where avid reading and fantasy play helped stave off boredom and fill emotional gaps for both of them. Even…

  6. The popular music heritage of the Dutch pirates: illegal radio and cultural identity

    NARCIS (Netherlands)

    A.J.C. van der Hoeven (Arno)

    2012-01-01

    textabstractThis article explores how cultural identities are negotiated in relation to the heritage of illegal radio in the Netherlands. The term ‘pirate radio’ commonly refers to the offshore radio stations that were broadcasting during the 1960s. These stations introduced commercial radio and

  7. Pirates in Historical Fiction and Nonfiction: A Twin-Text Unit of Study

    Science.gov (United States)

    Frye, Elizabeth M.; Trathen, Woodrow; Wilson, Kelley

    2009-01-01

    In this article, the authors outline an interdisciplinary unit of study using quality children's literatures, and they describe several instructional strategies and activities for reading and responding to historical fiction and informational texts. This "piratical study" integrates social studies and the language arts. Several social…

  8. Baywatch: two approaches to measure the effects of blocking access to The Pirate Bay

    NARCIS (Netherlands)

    Poort, J.; Leenheer, J.; van der Ham, J.; Dumitru, C.

    2013-01-01

    In the fight against the unauthorised sharing of copyright protected material, aka piracy, Dutch Internet Service Providers have been summoned by courts to block their subscribers’ access to The Pirate Bay (TPB) and related sites. This paper studies the effectiveness of this approach towards online

  9. La Somalie en mauvais État

    Directory of Open Access Journals (Sweden)

    Alain Gascon

    2008-05-01

    Full Text Available La Somalie a sombré depuis 1988 dans une guerre civile que rien ne semble pouvoir arrêter. Les chefs de guerre se disputent des portions du territoire en autant de repaires pour y organiser leurs trafics criminels. Expulsés de Mogadiscio par les milices des tribunaux islamiques, ils y sont revenus avec le gouvernement provisoire, réinstallé par l’Éthiopie. Toutefois, au Somaliland, au Nord, les autorités séparatistes ont rétabli la paix sur tout leur territoire, reconstruit les infrastructures et organisé des élections que personne n’a contestées, mais l’ONU, sous la pression conjuguée de la Ligue Arabe et de l’Union africaine, refuse de reconnaître l’indépendance de l’ex-colonie britannique. Après vingt ans d’indifférence à ce lointain conflit, l’État somalien est menacé de disparition.Since 1988 Somalia has sunk into an endless civil war. Warlords have been fighting over parts of the national territory in order to expand their criminal traffics. They were expelled from the capital by the Islamic court militias but they have returned to it when the Provisionnal Government of Somalia was restored by Ethiopia in Mogadisico. Under the pressures of the Arab League and of the African Union the United Nations have constantly refused to recognize the independence of Somaliland, a former British colony, despite its separatist government has brought peace on all their territory, rebuilt equipments and held fair elections. Twenty years of indifference to this remote conflict have threatened the Somalian state to death.

  10. Rainfall trends and variability in selected areas of Ethiopian Somali ...

    African Journals Online (AJOL)

    Moreover, proper spatial distribution of meteorological stations together with early warning system are required to further support local adaptive and coping strategies that the community designed towards rainfall variability in particular and climate change/disaster and risk at large. Keywords: Ethiopian Somali Region, Gode, ...

  11. THE STORY OF AMISOM'S SUCCESSFUL WAR AGAINST SOMALI ...

    African Journals Online (AJOL)

    dogmatic fundamentalism of Al Shabaab is at odds with the pragmatism demanded of Somali daily life. The decision to deploy a regional force into the Somalian imbroglio was something first mooted by Dr. Bashir Hamad Attalla, the Executive Secretary of the regional body the Intergovernmental Authority on Development ...

  12. The Wellbeing of Somali Refugees in Kampala: Perceived ...

    African Journals Online (AJOL)

    Although there is substantial research on the psychological wellbeing of refugees in psychology, especially in acculturation research, there is very little research assessing refugees' objective conditions of living. This study aims to bridge this gap by assessing the perceived satisfaction of Somali refugees' objective elements ...

  13. Targeting khat or targeting Somalis? A discourse analysis of project evaluations on khat abuse among Somali immigrants in Scandinavia

    Directory of Open Access Journals (Sweden)

    Nordgren Johan

    2015-09-01

    Full Text Available BACKGROUND – In Denmark, Norway and Sweden, the use of the psychoactive plant khat is widely seen as a social and health problem exclusively affecting the Somali immigrant population. Several projects by governmental and municipal bodies and agencies have been initiated to reduce khat use and abuse within this target population.

  14. La piratería como conflicto. Discursos sobre la propiedad intelectual en México

    NARCIS (Netherlands)

    Aguiar, José Carlos G.

    2010-01-01

    Este artículo da cuenta de la evolución de la protección de los derechos de autor (IPR, por sus siglas en inglés) con relación a las acciones antipiratería realizadas por el gobierno mexicano. La ‘guerra contra la piratería’ está fundada en la estructura legal del comercio mundial. El argu- mento

  15. A "domestic" history about the Danish-Somalis at a Museum in Århus

    DEFF Research Database (Denmark)

    Zoppi, Marco

    2017-01-01

    Interview piece with the project coordinator of the exhibition titled “Et somalisk hjem” (A Somali home), at Den Gamle By museum, Denmark. Published on WardheerNews on May 5, 2017. http://www.wardheernews.com/a-domestic-history-about-the-danish-somalis-at-a-museum-in-arhus/......Interview piece with the project coordinator of the exhibition titled “Et somalisk hjem” (A Somali home), at Den Gamle By museum, Denmark. Published on WardheerNews on May 5, 2017. http://www.wardheernews.com/a-domestic-history-about-the-danish-somalis-at-a-museum-in-arhus/...

  16. Educating Somali Immigrant and Refugee Students: A Review of Cultural-Historical Issues and Related Psychoeducational Supports

    Science.gov (United States)

    Walick, Christopher M.; Sullivan, Amanda L.

    2015-01-01

    Somali immigrants and refugees have entered the United States with increasing frequency due to civil war-induced violence and instability in their native country. The resultant increase of Somali students is of particular relevance to educators and school psychologists because Somali youth possess unique cultural backgrounds. In addition, refugee…

  17. The Czech Pirate Party in the 2010 and 2013 Parliamentary Elections and the 2014 European Parliament Elections: Spatial Analysis of Voter Support

    Directory of Open Access Journals (Sweden)

    Maškarinec Pavel

    2017-01-01

    Full Text Available The paper presents a spatial analysis of the Czech Pirate Party (Pirates voter support in the 2010 and 2013 parliamentary elections and the 2014 European Parliament elections. The main method applied for classifying electoral results was the spatial autocorrelation and spatial regression. The result of the analysis has shown that territorial support for the Pirates copies to a great extent the areas of high support for right-wing parties and simultaneously the areas exemplified by a high development potential. In the case of spatial characteristics, little support for the Pirates was shown in Moravia and higher in the Sudetenland in terms of determinants of support. Additionally to spatial regimes, inter-regional support for the Pirates was also influenced by other non-spatial characteristics, although the strength of their influence was relatively weak. The units which embodied a successful environment for voting for the Pirates were particularly characterized by greater urbanization and a greater number of entrepreneurs, while a lack of jobs and the older age structure, i.e. the signs that in the socio-economic, or socio-ecological sense define peripheral areas, negatively impacted the gains of the Pirates. Ambiguous influence was exercised by college-educated inhabitants, who in the parliamentary elections in 2010 and 2013 decreased the gains of the Pirates, however, in the elections to the European Parliament in 2014 a direction of relationship was modified and turned positive.

  18. Battue ou chasse à courre, en Somalie ou en Asie

    Directory of Open Access Journals (Sweden)

    Eric Frécon

    2009-01-01

    Full Text Available Le second semestre 2008 a été marqué par une explosion des actes de piraterie au large de la Corne de l’Afrique. Les efforts déployés en réaction se sont révélés être si désordonnés qu’ils risquent de ne pas être très efficaces. Plus à l’est, les riverains du détroit de Malacca ont réussi à chasser les pirates. Cependant, ce succès souvent montré en exemple demeure relatif et en aucun cas dû aux seules patrouilles mises en place.Since last August, there were markedly more attacks registered off the Horn of Africa. The lack of coordination between the numerous initiatives is making surveillance operations inefficient. Further in the east, the littoral States along the Malacca Straits have managed to expel the pirates. Nevertheless, this success – often showed as an example – is not total. Moreover, it is not only due to the sea and air patrols.

  19. They Bring Their Memories with Them: Somali Bantu Resettlement in a Globalized World

    Science.gov (United States)

    Smith, Yda Jean

    2010-01-01

    The Somali Bantu, arriving in the United States after many years in Kenyan refugee camps, face significant barriers to successful integration into American society. Those responsible for managing initial resettlement at the local level were not prepared to provide appropriate assistance to this group. The arrival of the Somali Bantu highlighted…

  20. HIV/AIDS knowledge and condom use among Somali and Sudanese immigrants in Denmark

    DEFF Research Database (Denmark)

    Lazarus, Jeff; Himedan, Himedan Mohammed; Østergaard, Lise Rosendal

    2006-01-01

    This study explores the knowledge, attitudes and practices among Somali and Sudanese immigrants in Denmark with regard to HIV/AIDS and condom use.......This study explores the knowledge, attitudes and practices among Somali and Sudanese immigrants in Denmark with regard to HIV/AIDS and condom use....

  1. Prevalence of Autism in Children Born to Somali Parents Living in Sweden: A Brief Report

    Science.gov (United States)

    Barnevik-Olsson, Martina; Gillberg, Christopher; Fernell, Elisabeth

    2008-01-01

    In a geographical area of Stockholm, with a relatively large Somali immigrant population, parents as well as teachers in special schools and staff at habilitation centres have raised concerns over whether children with a Somali background are over-represented in the total group of children with autism. The aim of the study was, therefore, to…

  2. El delito de piratería y el principio de justicia universal

    OpenAIRE

    Ramos Koprivitza, Ulises Sandal

    2014-01-01

    [ES] El incremento internacional del delito de piratería en los albores del Siglo XXI coloca, nuevamente, a esta actividad ilícita como un problema de actualidad para el Derecho penal, concomitantemente, al estudio del principio de justicia universal que se encuentra históricamente vinculado con este delito y que obliga al examen profundo de ambas figuras jurídicas para establecer la naturaleza y fundamento del principio de justicia universal; así como, los mecanismos adecuados para la repres...

  3. Views of Science Teaching and Learning by Immigrant Somali Elders: Perceptions of Conflict and Acceptance

    Science.gov (United States)

    Albrecht, Nancy Jean

    The gap between a student's home culture and that of classroom science may create challenges for students and families, especially those from recent immigrant cultures, including refugees. As a result, science learning in schools may require a form of cultural border crossing between home cultures and the culture of classroom science. Given this, as educators, how do we make these borders more porous for better science learning experiences? Using the frameworks of funds of knowledge, culturally relevant pedagogy, and socio-constructivism, this study focuses on the perspectives of Somali-American elders and parents about school science. Designed as an in-depth interview study, five purposefully selected participants were interviewed over a period of two years. The guiding questions for the study included: 1) What are the perceptions of Somali elders about school science? and 2) How do Somali elders believe science teaching and learning can facilitate Somali students' engagement in science?. Analysis of the interview data revealed that Somali-American adults have complicated perceptions of school science that include both conflicts and acceptance with current pedagogy and content. For example, science education was highly valued by both individuals and the Somali community, both as a way for individuals to attain economic prosperity and respect, but also as a way to lift up the Somali diaspora, both here and in their native homeland. On the other hand, science was also viewed as an abstract discipline with little connection to students' and families' everyday home lives. Moreover, due to the intrinsic role that Islam plays in traditional and contemporary Somali culture, several areas of science education, including geology, evolution and sex education, were viewed as problematic and unresolvable. Various potential areas of funds of knowledge and culturally relevant pedagogy were discussed including nutrition, food preparation and storage, health education, and

  4. A Stylistic Analysis of the Dialogues in Pirates of the Caribbean: On Strange Tides%A Stylistic Analysis of the Dialogues in Pirates of the Caribbean:On Strange Tides

    Institute of Scientific and Technical Information of China (English)

    李冯茹

    2017-01-01

    Dialogues in classical films are always the concentrated scripts studied by scholars. This thesis performs a stylistic analysis of dialogues from Pirates of the Caribbean: On Strange Tides at the levels of phonology, lexicon, syntax, semantics and pragmatics to make a good attempt in the application of stylistic analysis.

  5. Attitudes toward female circumcision among Somali immigrants in Oslo: a qualitative study.

    Science.gov (United States)

    Gele, Abdi A; Kumar, Bernadette; Hjelde, Karin Harsløf; Sundby, Johanne

    2012-01-01

    Due to its negative impact on public health, female circumcision (FC) has gained increased attention from international communities and the Norwegian public in recent decades. In 1995, the Norwegian government outlawed the practice and simultaneously developed a package of measures aimed at preventing and ultimately eradicating FC in Norway. Like many other Western countries, immigrants of Somali descent constitute the largest immigrant group in Norway from countries with FC traditions. Although this immigrant group is often perceived as a cultural society that supports FC generally as a practice, there appears to be a lack of studies that explore the impact of acculturation and the Western social context on Somali immigrants' attitudes toward the practice. Against this background, this paper explores the attitudes of Somalis living in Oslo, Norway to the practice of FC. Findings from this qualitative study indicate that Somalis in Oslo have, to a large extent, changed their attitude toward the practice. This was proven by the presence in Oslo of a large number of Somali parents who left their daughters uncut as well as Somali girls, boys, men, and women who attribute being uncircumcised a high status. This study adds to the knowledge of the process of abandonment of FC among immigrants in the Western countries. The study highlights the success that has been achieved in improving attitudes toward the practice of the Somali community in Oslo, Norway, as well as emerging challenges that need to be addressed further.

  6. La piratería como conflicto. Discursos sobre la propiedad intelectual en México

    Directory of Open Access Journals (Sweden)

    José Carlos G. Aguiar

    2010-09-01

    Full Text Available Este artículo da cuenta de la evolución de la protección de los derechos de autor (IPR, por sus siglas en inglés con relación a las acciones antipiratería realizadas por el gobierno mexicano. La ‘guerra contra la piratería’ está fundada en la estructura legal del comercio mundial. El argumento central del autor es que la criminalización de la piratería no resulta de un proceso de interés nacional que tenga como objetivo promover e intensificar la propiedad intelectual o el estado de derecho, sino que surge de una perspectiva punitiva emanada de las redes de intereses internacionales y actores transnacionales propios del neoliberalismo global.AbstractThis article examines the evolution of intellectual property rights (IPR protection in relation to anti-piracy actions undertaken by the Mexican government. The ‘war against piracy’ is based on the world trade legal structure. The author’s central argument is that the criminalization of piracy is not the result of a process of national interest which has as its objective the promotion and intensification of intellectual property rights or the rule of law but, rather, emerges from a punitive perspective emanating from networks of international interests and transnational actors characteristic of global neoliberalism.

  7. Cloning, killing, and identity.

    Science.gov (United States)

    McMahan, J

    1999-01-01

    One potentially valuable use of cloning is to provide a source of tissues or organs for transplantation. The most important objection to this use of cloning is that a human clone would be the sort of entity that it would be seriously wrong to kill. I argue that entities of the sort that you and I essentially are do not begin to exist until around the seventh month of fetal gestation. Therefore to kill a clone prior to that would not be to kill someone like you or me but would be only to prevent one of us from existing. And even after one of us begins to exist, the objections to killing it remain comparatively weak until its psychological capacities reach a certain level of maturation. These claims support the permissibility of killing a clone during the early stages of its development in order to use its organs for transplantation. PMID:10226909

  8. MEAT-GOAT MARKET ANALYSIS: A PILOT STUDY OF THE SOMALI MARKET IN COLUMBUS, OH

    OpenAIRE

    Worley, C. Thomas; Ellerman, John; Mangione, Dave; West, Travis; Yang, Y.

    2004-01-01

    This case study focuses on meat goat marketing involving one distinct immigrant group residing in one area of Columbus, Ohio: the Somalis. There are about 20,000-25,000 Somalis living in Columbus, the second largest concentration of Somalian immigrants in the U.S. after Minneapolis-St. Paul, Minnesota. It is estimated that Columbus Somalis consume the meat from about 14,000 goats each year. The objective of this pilot study is to analyze the meat goat marketing and consumption patterns of the...

  9. Raising Citizens: Parenting Education Classes and Somali Mothers’ Experiences of Childrearing in Canada

    Directory of Open Access Journals (Sweden)

    Melissa Fellin

    2015-09-01

    Full Text Available Mothers are viewed as the people who are raising future citizens of Canada; therefore, their parenting practices are being targeted for intervention by civic organizations funded by the state. In this article, I argue that modernity narratives and neoliberalism approaches to mothering inform parenting education classes for Somali refugee women to Canada. Thus, Somali women are often seen as victims. Stereotyped identities conceal their social and historical agency. This research draws on 15 individual interviews with Somali mothers and participant- observation in two parenting education classes in Canada.

  10. Somali Immigrant Perceptions of Mental Health and Illness: An Ethnonursing Study.

    Science.gov (United States)

    Wolf, Kimberly M; Zoucha, Rich; McFarland, Marilyn; Salman, Khlood; Dagne, Ahmed; Hashi, Naimo

    2016-07-01

    Knowledge of Somali immigrants' mental health care beliefs and practices is needed so that nurses can promote culturally congruent care. The purpose of this study was to explore, discover, and understand mental health meanings, beliefs, and practices from the perspective of immigrant Somalis. Leininger's qualitative ethnonursing research method was used. Thirty informants (9 key and 21 general) were interviewed in community settings. Leininger's ethnonursing enablers and four phases of analysis for qualitative data were used. Analysis of the interviews revealed 21 categories and nine patterns from which two main themes emerged. The themes are the following: (a) Our religion significantly influences our mental health and (b) Our tribe connectedness, cultural history, and khat usage are significant in mental health. Somali cultural and religious beliefs and practices influence their health care choices. The findings will improve care by promoting culturally congruent care for the Somali immigrant population. © The Author(s) 2014.

  11. Discrimination and mental health among Somali refugee adolescents: the role of acculturation and gender.

    Science.gov (United States)

    Ellis, B Heidi; MacDonald, Helen Z; Klunk-Gillis, Julie; Lincoln, Alisa; Strunin, Lee; Cabral, Howard J

    2010-10-01

    This study examines the role of social identity (acculturation and gender) in moderating the association between discrimination and Somali adolescent refugees' mental health. Participants were English-speaking Somali adolescent refugees between the ages of 11 and 20 (N = 135). Perceived discrimination, trauma history, posttraumatic stress disorder (PTSD), depressive symptoms, and behavioral acculturation were assessed in structured interviews. Fourteen in-depth qualitative interviews and 3 focus groups were also conducted. Results indicated that discrimination was common and associated with worse mental health. For girls, greater Somali acculturation was associated with better mental health. Also, the association between discrimination and PTSD was less strong for girls who showed higher levels of Somali acculturation. For boys, greater American acculturation was associated with better mental health, and the association between discrimination and depression was less strong for boys with higher levels of American acculturation. © 2010 American Orthopsychiatric Association.

  12. Somalis giving birth in Sweden: a challenge to culture and gender specific values and behaviours.

    Science.gov (United States)

    Wiklund, H; Aden, A S; Högberg, U; Wikman, M; Dahlgren, L

    2000-06-01

    Giving birth in a foreign country implies going through a life event with little or no access to your own traditions and social support. The aim of this study was to study the childbirth experiences of Somali women and men in Sweden. Qualitative. Nine women and seven men were interviewed. Data collection was characterised by an openness to new ideas during the interview and the interviews were analysed according to the grounded theory technique. The meeting of Somalis with Swedish antenatal and delivery care was a multicultural event. It revealed social, medical, cultural and gender factors advocating space in the arena of childbirth. The Somalis constituted a homogeneous group with regard to their cultural belonging and motives for exile. The subjects were heterogeneous in that they represented a great variety in social and demographic background as well as in experiences, feelings and modes of expression. One striking finding was the Somali man's dramatic entrance into childbirth, which seemed to have a strong impact on the Somali woman's well-being during delivery. The study showed difficulties in getting used to the Swedish model of parenthood and in finding new role divisions in the couple relationship. Some of the subjects had experienced a strengthening of their marriage and an increased understanding of each other. Others commented that various aspects of traditional womanhood and manhood were lost as a result of the unfamiliar gender structures in Sweden. The Somalis' experiences of childbirth in Sweden can be understood by using the theoretical concept of gender, rather than culture. Our own and other studies show that women and men may have different frames of reference in childbirth, where the women mainly focus on biological circumstances and the men on the social and cultural aspects of birth. The Somali couple were found to be vulnerably positioned, with the professionals having the important role of supporting and empowering Somali parents.

  13. Diabetes Health Literacy Among Somali Patients with Diabetes Mellitus in a US Primary Care Setting.

    Science.gov (United States)

    Njeru, Jane W; Hagi-Salaad, Misbil F; Haji, Habibo; Cha, Stephen S; Wieland, Mark L

    2016-06-01

    The purpose of this study was to describe diabetes literacy among Somali immigrants with diabetes and its association with diabetes outcomes. Among Somali immigrants in North America, the prevalence of diabetes exceeds that of the general population, and their measures of diabetes control are suboptimal when compared with non-Somali patients. Diabetes literacy is an important mediator of diabetes outcomes in general populations that has not been previously described among Somali immigrants and refugees. Diabetes literacy was measured using a translated version of the spoken knowledge in low literacy in diabetes (SKILLD) scale among Somali immigrants and refugees with type 2 diabetes. Diabetes outcome measures, including hemoglobin A1C, low-density lipoprotein (LDL) cholesterol, and blood pressure, were obtained for each patient. Multivariate logistic regression was used to assess associations between diabetes literacy and diabetes outcomes. Among 50 Somali patients with diabetes who completed the survey, the mean SKILLD score was low (42.2 %). The diabetes outcome measures showed a mean hemoglobin A1C of 8 %, LDL cholesterol of 99.17 mg/dL (2.57 mmol/L), systolic blood pressure of 130.9 mmHg, and diastolic blood pressure of 70.2 mmHg. There was no association between diabetes literacy scores and diabetes outcome measures. Somali patients with diabetes mellitus had low diabetes literacy and suboptimal measures of diabetes disease control. However, we found no association between diabetes literacy and diabetes outcomes. Future work aimed at reduction of diabetes-related health disparities among Somali immigrants and refugees to high-income countries should go beyond traditional means of patient education for low-literacy populations.

  14. Attitudes toward female circumcision among Somali immigrants in Oslo: a qualitative study

    Directory of Open Access Journals (Sweden)

    Gele AA

    2012-01-01

    Full Text Available Abdi A Gele1,2, Bernadette Kumar3, Karin Harsløf Hjelde3, Johanne Sundby21The Department of Social Science, Oslo University College, 2Section for International Health, Department of General Practice and Community Medicine, University of Oslo, 3Norwegian Center for Minority Health Research, Oslo, NorwayAbstract: Due to its negative impact on public health, female circumcision (FC has gained increased attention from international communities and the Norwegian public in recent decades. In 1995, the Norwegian government outlawed the practice and simultaneously developed a package of measures aimed at preventing and ultimately eradicating FC in Norway. Like many other Western countries, immigrants of Somali descent constitute the largest immigrant group in Norway from countries with FC traditions. Although this immigrant group is often perceived as a cultural society that supports FC generally as a practice, there appears to be a lack of studies that explore the impact of acculturation and the Western social context on Somali immigrants’ attitudes toward the practice. Against this background, this paper explores the attitudes of Somalis living in Oslo, Norway to the practice of FC. Findings from this qualitative study indicate that Somalis in Oslo have, to a large extent, changed their attitude toward the practice. This was proven by the presence in Oslo of a large number of Somali parents who left their daughters uncut as well as Somali girls, boys, men, and women who attribute being uncircumcised a high status. This study adds to the knowledge of the process of abandonment of FC among immigrants in the Western countries. The study highlights the success that has been achieved in improving attitudes toward the practice of the Somali community in Oslo, Norway, as well as emerging challenges that need to be addressed further.Keywords: female circumcision, attitude, behavior, immigrants, Somalis

  15. Somali Piracy and Anti-Shipping Activity Messages: Lessons for a Successful Counterpiracy Strategy

    Science.gov (United States)

    2014-06-01

    with the inclusion of ASAM reporting numbers alongside the IMO and IMB statistics from 1998 to 2002 as an additional comparison. 16 Table 1...pirate attack. The IMB’s definition of piracy is more inclusive . The second problem is underreporting. Reporting minor pirate attacks usually raises...piratas somalíes en el océano índico (2005-2013): Evolución y modus operandi. Revista del Instituto Español de Estudios Estratégicos, 1(1). Haig

  16. Views of Somali women and men on the use of faith-based messages promoting breast and cervical cancer screening for Somali women: a focus-group study

    Directory of Open Access Journals (Sweden)

    Rebekah Pratt

    2017-03-01

    Full Text Available Abstract Background Screening rates for breast and cervical cancer for Muslim women in the United States are low, particularly for first-generation immigrants. Interpretations of the Muslim faith represent some of the barriers for breast and cervical cancer screening. Working to understand how faith influences breast and cervical screening for Somali women, and working with the community to identify and utilize faith-based assets for promoting screening, may lead to life-saving changes in screening behaviors. Methods We partnered with an Imam to develop faith-based messages addressing the concerns of modesty and predetermination and promoting cancer testing and screening. A total of five focus groups were convened, with 34 Somali women (three groups and 20 Somali men (two groups. Each focus group first discussed participant views of breast and cervical cancer screening in general and then viewed and discussed video clips of the Imam delivering the faith-based messages. Results Both Somali women and men had an overwhelmingly positive response to the faith-based messages promoting breast and cervical cancer screening. The faith-based messages appeared to reinforce the views of those who were already inclined to see screening positively, with participants describing increased confidence to engage in screening. For those who had reservations about screening, there was feedback that the faith-based messages had meaningfully influenced their views. Conclusions Somali immigrant women and men found faith-based messages addressing topics of predestination and modesty and encouraging the use of screening and treatment to be both acceptable and influential. Faith can play an important role as an asset to promote breast and cervical cancer screening, and there may be substantial benefits to adding faith-based messaging to other interventions that focus on improving screening uptake. This may help to address health disparities for Somali women in this area.

  17. Body composition and net energy requirements of Brazilian Somali lambs

    Directory of Open Access Journals (Sweden)

    Elzânia S. Pereira

    2014-12-01

    Full Text Available The aim of this study was to determine the energy requirements for maintenance (NEm and growth of 48 Brazilian Somali ram lambs with an average initial body weight of 13.47±1.76 kg. Eight animals were slaughtered at the trials beginning as a reference group to estimate the initial empty body weight (EBW and body composition. The remaining animals were assigned to a randomised block design with eight replications per block and five diets with increasing metabolisable energy content (4.93, 8.65, 9.41, 10.12 and 11.24 MJ/kg dry matter. The logarithm of heat production was regressed against metabolisable energy intake (MEI, and the NEm (kJ/kg0.75 EBW/day were estimated by extrapolation, when MEI was set at zero. The NEm was 239.77 kJ/kg0.75 EBW/day. The animal’s energy and EBW fat contents increased from 11.20 MJ/kg and 208.54 g/kg to 13.54 MJ/kg and 274.95 g/kg of EBW, respectively, as the BW increased from 13 to 28.70 kg. The net energy requirements for EBW gain increased from 13.79 to 16.72 MJ/kg EBW gain for body weights of 13 and 28.70 kg. Our study indicated the net energy requirements for maintenance in Brazilian Somali lambs were similar to the values commonly recommended by the United States’ nutritional system, but lower than the values recommended by Agricultural Research Council and Commonwealth Scientific and Industrial Research Organization. Net requirements for weight gain were less compared to the values commonly recommended by nutritional system of the United States.

  18. Air-Sea Interaction in the Somali Current Region

    Science.gov (United States)

    Jensen, T. G.; Rydbeck, A.

    2017-12-01

    The western Indian Ocean is an area of high eddy-kinetic energy generated by local wind-stress curl, instability of boundary currents as well as Rossby waves from the west coast of India and the equatorial wave guide as they reflect off the African coast. The presence of meso-scale eddies and coastal upwelling during the Southwest Monsoon affects the air-sea interaction on those scales. The U.S. Navy's Coupled Ocean-Atmosphere Mesoscale Prediction System (COAMPS) is used to understand and quantify the surface flux, effects on surface waves and the role of Sea Surface Temperature anomalies on ocean-atmosphere coupling in that area. The COAMPS atmosphere model component with 9 km resolution is fully coupled to the Navy Coastal Ocean Model (NCOM) with 3.5 km resolution and the Simulating WAves Nearshore (SWAN) wave model with 10 km resolution. Data assimilation using a 3D-variational approach is included in hindcast runs performed daily since June 1, 2015. An interesting result is that a westward jet associated with downwelling equatorial Rossy waves initiated the reversal from the southward Somali Current found during the northeast monsoon to a northward flow in March 2016 more than a month before the beginning of the southwest monsoon. It is also found that warm SST anomalies in the Somali Current eddies, locally increase surface wind speed due to an increase in the atmospheric boundary layer height. This results in an increase in significant wave height and also an increase in heat flux to the atmosphere. Cold SST anomalies over upwelling filaments have the opposite impacts on air-sea fluxes.

  19. Fighting Pirates

    DEFF Research Database (Denmark)

    Lucas, Edward

    two centuries. Despite the considerable scholarly interest in examining how powerful states go about suppressing piracy, however, there has been little in-depth examination of why these states are willing expend resources combating piracy in the first place. When this question is addressed, counter...

  20. Upper limb therapy in children with cerebral palsy (CP – The Pirate Group

    Directory of Open Access Journals (Sweden)

    Pawlak Marta

    2017-12-01

    Full Text Available Introduction: Children with cerebral palsy (CP in the form of spastic hemiplegia experience numerous difficulties concerning an affected upper limb such as reaching for objects, gripping or manipulating them. These limitations affect their everyday activity. Conducting an effective and simultaneously an interesting therapy aimed at meeting the child’s individual needs and improving upper limb function is a challenge for a physiotherapist. The aim of the study was to assess the effectiveness of upper limb therapy carried out within the project titled “The Pirate Group” based on Constraint-Induced Movement Therapy (CIMT and Bimanual Training (BIT conducted in a specially arranged environment. Material and methods: The research included 16 children with CP in the form of spastic hemiplegia. Mean age of the study participants was 4.23 years. The children underwent a two-week Constraint-Induced Movement Therapy (CIMT combined with Bimanual Training (BIT. In order to evaluate the effects of the therapy, each child underwent the Assisting Hand Assessment (AHA prior to the therapy and after its completion. Results: Statistical analysis revealed a significant difference (p<0.05 between the results of AHA prior to and after the therapy (t(14=9.12, p<0.0001. An improvement in the affected upper limb function was noted in all the children participating in the research. Conclusions: The project titled “The Pirate Group”, based on CIMT and BIT is an effective therapeutic intervention which improves spontaneous activity of the affected upper limb in children with hemiplegia.

  1. "A Somali girl is Muslim and does not have premarital sex. Is vaccination really necessary?" A qualitative study into the perceptions of Somali women in the Netherlands about the prevention of cervical cancer.

    Science.gov (United States)

    Salad, Jihan; Verdonk, Petra; de Boer, Fijgje; Abma, Tineke A

    2015-08-21

    Participation in Human Papillomavirus (HPV) vaccination and Papanicolaou Screening (Pap smears) is low among ethnic minorities in the Netherlands and hardly any information is available about the cervical cancer prevention methods of Somali women living in the diaspora. This qualitative study, based on the Health Belief Model (HBM) and an intersectionality-based framework, explores the perceptions of Somali women living in the Netherlands regarding measures to prevent cervical cancer. Semi-structured interviews have been conducted with young Somali women aged 17-21 years (n = 14) and Somali mothers aged 30-46 years (n = 6). Two natural group discussions have been conducted with 12 and 14 Somali mothers aged 23-66 years. The collected data has been analyzed thematically for content. In this study, we have identified perceived barriers to the use of preventive measures across three major themes: (1) Somali women and preventive healthcare; (2) Language, knowledge, and negotiating decisions; and (3) Sexual standards, culture, and religion. Many issues have been identified across these themes, e.g., distrust of the Dutch health care system or being embarrassed to get Pap smears due to Female Genital Mutilation (FGM) and having a Dutch, male practitioner; or a perceived low susceptibility to HPV and cancer because of the religious norms that prohibit sex before marriage. Current measures in the Netherlands to prevent women from developing cervical cancer hardly reach Somali women because these women perceive these kinds of preventative measures as not personally relevant. Dutch education strategies about cervical cancer deviate from ways of exchanging information within the Somali community. Teachers can provide culturally sensitive information to young Somali women in schools. For Somali mothers, oral education (e.g., poetry or theater) about the Dutch health care system and men's roles in HPV transmission may be useful. An intersectional approach, grounded in

  2. Somali women's view of physical activity--a focus group study.

    Science.gov (United States)

    Persson, Gerthi; Mahmud, Amina Jama; Hansson, Eva Ekvall; Strandberg, Eva Lena

    2014-10-23

    Physical inactivity presents a major public health challenge and is estimated to cause six to ten percent of the major non-communicable diseases. Studies show that immigrants, especially women, have an increased risk of non-communicable diseases compared to ethnic Swedes. Somali immigrant women have increased rates of overweight and obesity, low fitness levels and low levels of cardiorespiratory fitness compared to non-immigrant women. These findings suggest that Somali women are at increased risk of developing lifestyle-related diseases. Few studies explore determinants of physical activity among Somali women. The aim of this study was to explore Somali women's views and experiences of physical activity after migration to Sweden. A qualitative focused ethnographic approach was used in this study. Four focus groups were conducted with twenty-six Somali women ranging from 17 to 67 years of age. Focus group discussions were recorded, transcribed verbatim and analysed using qualitative content analysis. The analysis resulted in four main themes and ten categories: Life in Somalia and Life in Sweden, Understanding and enhancing health and Facilitators and barriers to physical activity. Great differences were seen between living in Somalia and in Sweden but also similarities such as finding time to manage housework, the family and the health of the woman. The extended family is non-existent in Sweden, making life more difficult. Health was considered a gift from God but living a healthy life was perceived as the responsibility of the individual. Misconceptions about enhancing health occurred depending on the woman's previous life experience and traditions. There was an awareness of the importance of physical activity among the participants but lack of knowledge of how to enhance activity on an individual basis. Enhancing factors to an active lifestyle were identified as being a safe and comfortable environment. Some barriers, such as climate, lack of motivation and time

  3. Cultural translation of refugee trauma: Cultural idioms of distress among Somali refugees in displacement.

    Science.gov (United States)

    Im, Hyojin; Ferguson, Aidan; Hunter, Margaret

    2017-01-01

    Westernized approaches to mental health care often place limited emphasis on refugees' own experiences and cultural explanations of symptoms and distress. In order to effectively assess community mental health needs and develop interventions grounded in local needs, mental health programs need to be informed by an understanding of cultural features of mental health, including cultural idioms of distress (CIDs). The current study aims to explore CIDs among Somali refugees displaced in Kenya to understand mental health needs in cultural context and serve the community in a culturally responsive and sensitive manner. This research was conducted as a two-phase qualitative study. First, key informant interviews with Somali mental health stakeholders generated a list of 7 common Somali CIDs: buufis, buqsanaan, welwel, murug, qaracan, jinn, and waali. Typologies of each CID were further explored through four focus group interviews with Somali community members. The findings from a template analysis revealed Somali lay beliefs on how trauma and daily stressors are experienced and discussed in the form of CIDs and how each term is utilized and understood in attributing symptoms to associated causes. This study highlights the need to incorporate colloquial terms in mental health assessment and to adopt a culturally relevant framework to encourage wider utilization of services and religious/spiritual support systems.

  4. The development and evaluation of alternative communication strategies to facilitate interactions with Somali refugees in primary care: a preliminary study

    Directory of Open Access Journals (Sweden)

    Marianne Johnson

    2006-09-01

    Each task was timed and scored for level of correctness; feedback was gained from Somalis and experimenters' observations were noted. Participants clearly found the computerised devices with Somali speech output easier to use and more acceptable than the simpler paper-based device.

  5. Prevalence of Autism in Children of Somali Origin Living in Stockholm: Brief Report of an At-Risk Population

    Science.gov (United States)

    Barnevik-Olsson, Martina; Gillberg, Christopher; Fernell, Elisabeth

    2010-01-01

    This work was a follow-up study (birth years 1999-2003) of the prevalence of autism in children of Somali background living in the county of Stockholm, Sweden. In a previous study (birth years 1988-98), the prevalence of autism associated with learning disability was found to be three to four times higher among Somali children compared with other…

  6. Theriocide: Naming Animal Killing

    Directory of Open Access Journals (Sweden)

    Piers Beirne

    2014-08-01

    Full Text Available In this essay I recommend ‘theriocide’ as the name for those diverse human actions that cause the deaths of animals. Like the killing of one human by another, theriocide may be socially acceptable or unacceptable, legal or illegal. It may be intentional or unintentional and may involve active maltreatment or passive neglect. Theriocide may occur one-on-one, in small groups or in large-scale social institutions. The numerous and sometimes intersecting sites of theriocide include intensive rearing regimes; hunting and fishing; trafficking; vivisection; militarism; pollution; and human-induced climate change. If the killing of animals by humans is as harmful to them as homicide is to humans, then the proper naming of such deaths offers a remedy, however small, to the extensive privileging of human lives over those of other animals. Inevitably, the essay leads to a shocking question: Is theriocide murder?

  7. Oil is killing Africa

    International Nuclear Information System (INIS)

    Paris, H.

    2007-09-01

    Sub-Saharan Africa, with its mining and petroleum resources, is still the object of covetous desires from developed countries. The Gulf of Guinea is a promising area and probably the future battlefield of the 21. century. The fighters of this war are the African people and the big powers, the USA and China at the head, who call upon mercenaries to get their share of this fabulous treasure. Oil was a chance for Africa, but now oil is killing it

  8. Being a bridge: Swedish antenatal care midwives' encounters with Somali-born women and questions of violence; a qualitative study.

    Science.gov (United States)

    Byrskog, Ulrika; Olsson, Pia; Essén, Birgitta; Allvin, Marie-Klingberg

    2015-01-16

    Violence against women is associated with serious health problems, including adverse maternal and child health. Antenatal care (ANC) midwives are increasingly expected to implement the routine of identifying exposure to violence. An increase of Somali born refugee women in Sweden, their reported adverse childbearing health and possible links to violence pose a challenge to the Swedish maternity health care system. Thus, the aim was to explore ways ANC midwives in Sweden work with Somali born women and the questions of exposure to violence. Qualitative individual interviews with 17 midwives working with Somali-born women in nine ANC clinics in Sweden were analyzed using thematic analysis. The midwives strived to focus on the individual woman beyond ethnicity and cultural differences. In relation to the Somali born women, they navigated between different definitions of violence, ways of handling adversities in life and social contexts, guided by experience based knowledge and collegial support. Seldom was ongoing violence encountered. The Somali-born women's' strengths and contentment were highlighted, however, language skills were considered central for a Somali-born woman's access to rights and support in the Swedish society. Shared language, trustful relationships, patience, and networking were important aspects in the work with violence among Somali-born women. Focus on the individual woman and skills in inter-cultural communication increases possibilities of overcoming social distances. This enhances midwives' ability to identify Somali born woman's resources and needs regarding violence disclosure and support. Although routine use of professional interpretation is implemented, it might not fully provide nuances and social safety needed for violence disclosure. Thus, patience and trusting relationships are fundamental in work with violence among Somali born women. In collaboration with social networks and other health care and social work professions, the

  9. Relationships Between English Language Proficiency, Health Literacy, and Health Outcomes in Somali Refugees.

    Science.gov (United States)

    Murphy, Jessica E; Smock, Laura; Hunter-Adams, Jo; Xuan, Ziming; Cochran, Jennifer; Paasche-Orlow, Michael K; Geltman, Paul L

    2018-06-15

    Little is known about the impacts of health literacy and English proficiency on the health status of Somali refugees. Data came from interviews in 2009-2011 of 411 adult Somali refugees recently resettled in Massachusetts. English proficiency, health literacy, and physical and mental health were measured using the Basic English Skills Test Plus, the Short Test of Health Literacy in Adults, and the Physical and Mental Component Summaries of the Short Form-12. Associations were analyzed using multiple linear regression. In adjusted analyses, higher English proficiency was associated with worse mental health in males. English proficiency was not associated with physical health. Health literacy was associated with neither physical nor mental health. Language proficiency may adversely affect the mental health of male Somali refugees, contrary to findings in other immigrant groups. Research on underlying mechanisms and opportunities to understand this relationship are needed.

  10. Hijacked evidence-based medicine: stay the course and throw the pirates overboard.

    Science.gov (United States)

    Ioannidis, John P A

    2017-04-01

    The article discusses a number of criticisms that have been raised against evidence-based medicine, such as focusing on benefits and ignoring adverse events; being interested in averages and ignoring the wide variability in individual risks and responsiveness; ignoring clinician-patient interaction and clinical judgement; leading to some sort of reductionism; and falling prey to corruption from conflicts of interest. I argue that none of these deficiencies are necessarily inherent to evidence-based medicine. In fact, work in evidence-based medicine has contributed a lot towards minimizing these deficiencies in medical research and medical care. However, evidence-based medicine is paying the price of its success: having become more widely recognized, it is manipulated and misused to support subverted or perverted agendas that are hijacking its reputation value. Sometimes the conflicts behind these agendas are so strong that one worries about whether the hijacking of evidence-based medicine is reversible. Nevertheless, evidence-based medicine is a valuable conceptual toolkit and it is worth to try to remove the biases of the pirates who have hijacked its ship. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Looking Islam in the Teeth: The Social Life of a Somali Toothbrush.

    Science.gov (United States)

    Laird, Lance D; Barnes, Linda L; Hunter-Adams, Jo; Cochran, Jennifer; Geltman, Paul L

    2015-09-01

    The Arabic miswak (Somali, adayge) is a tooth-cleaning stick from the Salvadora persica plant. In this article, we trace the social life of a "thing," examining meanings inscribed in the stick brush, drawing on interviews with 82 Somali refugees in Massachusetts and an analysis of local and transnational science and marketing. The miswak toothbrush symbolizes relationships to nature, homeland culture, global Islam, globalizing dental medicine, and the divine as it intersects with the lives of producers, marketers, distributors, and users, creating hybrid cultural forms in new contexts. © 2015 by the American Anthropological Association.

  12. Analysing the Wrongness of Killing

    DEFF Research Database (Denmark)

    Di Nucci, Ezio

    2014-01-01

    This article provides an in-depth analysis of the wrongness of killing by comparing different versions of three influential views: the traditional view that killing is always wrong; the liberal view that killing is wrong if and only if the victim does not want to be killed; and Don Marquis‟ future...... of value account of the wrongness of killing. In particular, I illustrate the advantages that a basic version of the liberal view and a basic version of the future of value account have over competing alternatives. Still, ultimately none of the views analysed here are satisfactory; but the different...

  13. "We would never forget who we are": resettlement, cultural negotiation, and family relationships among Somali Bantu refugees.

    Science.gov (United States)

    Frounfelker, Rochelle L; Assefa, Mehret T; Smith, Emily; Hussein, Aweis; Betancourt, Theresa S

    2017-11-01

    Somali refugees are resettling in large numbers in the US, but little is known about the Somali Bantu, an ethnic minority within this population. Refugee youth mental health is linked to the functioning of the larger family unit. Understanding how the process of culturally adjusting to life after resettlement relates to family functioning can help identify what kind of interventions might strengthen families and lead to better mental health outcomes for youth. This paper seeks to address the following research questions: (1) How do different groups of Somali Bantu refugees describe their experiences of culturally adapting to life in the US?; and (2) How, if at all, do processes of cultural adaptation in a new country affect Somali Bantu family functioning? We conducted 14 focus groups with a total of 81 Somali Bantu refugees in New England. Authors analyzed focus groups using principles of thematic analysis to develop codes and an overarching theoretical model about the relationship between cultural adaptation, parent-child relationships, and family functioning. Views and expectations of parent-child relationships were compared between Somali Bantu youth and adults. Cultural negotiation was dependent upon broader sociocultural contexts in the United States that were most salient to the experience of the individual. Adult and youth participants had conflicting views around negotiating Somali Bantu culture, which often led to strained parent-child relationships. In contrast, youth sibling relationships were strengthened, as they turned to each other for support in navigating the process of cultural adaptation.

  14. Somali Piracy: An Age-Old Solution to a Modern Day Problem

    Science.gov (United States)

    2010-05-19

    under international law over acts ofpiracy. 12 The,International Maritime Bureau (IMB), the maritime branch of the International Chamber of Commerce , defines...International Chamber of Commerce Commercial Crime Services. January 14,2010. http://www.icc-ccs.org (accessed January 18,2010). 20 that pirates are...from the International Maritime Bureau Piracy Reporting Center, a division International Chamber of Commerce . 61 U.S. Africa Command, "United States

  15. Somali Families in Norway: : A Critical Review of The Changing Socio-structural Situation and it's Consequence for the Family

    OpenAIRE

    Gabowduale, Kassim Gabowduale

    2010-01-01

    An increasing number of Somali families have been flashed out of their homes and forced to migrate as a result of the ongoing conflict in Somalia. With the outbreak of the civil war in Somalia in the late eighties and early nineties, a large exodus of refugees fled the country. There are almost twenty three thousand Somalis living in Norway today; the majority of them settled in and around Oslo according to Statistics Norway (Henriksen 2008). Upon arrival, Somalis, still suffering from the tr...

  16. Beyond Culture and Language: Access to Diabetes Preventive Health Services among Somali Women in Norway.

    Science.gov (United States)

    Gele, Abdi A; Torheim, Liv Elin; Pettersen, Kjell Sverre; Kumar, Bernadette

    2015-01-01

    Despite the high prevalence of type 2 diabetes in some immigrant and refugee communities in Norway, there is very little information available on their utilization of diabetes prevention interventions, particularly for women from Somali immigrant communities. A qualitative study of 30 Somali immigrant women aged 25 years and over was carried out in the Oslo area. Unstructured interviews were used to explore women's knowledge of diabetes, their access to preventive health facilities, and factors impeding their reception of preventive health programs targeted for the prevention of type 2 diabetes. The study participants were found to have a good knowledge of diabetes. They knew that a sedentary lifestyle and unhealthy diet are among the risk factors for diabetes. Regardless of their knowledge, participants reported a sedentary lifestyle accompanied with the consumption of an unhealthy diet. This was attributed to a lack of access to tailored physical activity services and poor access to health information. Considering gender-exclusive training facilities for Somali immigrant women and others with similar needs, in addition to access to tailored health information on diet, may encourage Somali women to adopt a healthy lifestyle, and it will definitely contribute to a national strategy for the prevention of diabetes.

  17. Norwegian-Somali Parents Who Send Their Children to Schools in Somalia

    Science.gov (United States)

    Thomas, Paul

    2016-01-01

    The perplexing numbers of Somali children withdrawn from schools in Norway and sent to Somalia is the concern of this study. These students are often brought back and re-enroll later as adolescents with concomitant educational challenges. The findings are critically analyzed employing John Ogbu's cultural ecology of minorities and a CHAT-based…

  18. Liminalities: expanding and constraining the options of Somali youth in the Helsinki Metropolitan Area

    Directory of Open Access Journals (Sweden)

    Alitolppa-Niitamo Anne

    2001-01-01

    Full Text Available Somali youth, "the generation in-between", who arrived in Finland in their early teens or as teenagers in the 1990shave faced specific challenges in Somali diaspora in Finland. Their voice is often ambiguous in the processes of cultural construction and ethnic reconstruction. Dissonant acculturation and role reversal within the families and a family culture that emphasizes strong parental authority place these young people in a liminal position. Measures which balance the pace of the acculturation between the generations could alleviate the situation In addition, the diasporic consciousness and transnational activities among Somalis along with the ethos of 'integration' within the mainstream institutions challenge Somali youth. They may find themselves 'betwixt and between' various future orientations. This should be acknowledged in educational planning, for example. While liminal states may open up new opportunities, it is claimed that several simultaneous states of liminality may be confusing for a young person, and may create risks for becoming marginal from societal and cultural classifications, as well as limit a person from finding his/her own group of reference.

  19. "Where to Start": Learning from Somali Bantu Refugee Students and Families

    Science.gov (United States)

    Roxas, Kevin; Roy, Laura

    2012-01-01

    This article provides an overview of research conducted with Somali Bantu refugee students in two contexts: Michigan and South Texas. We provide recommendations for outreach to refugee families and their families, for instruction in the classroom, for advising and support for these children, and for implementing school and district policy as it…

  20. Health literacy: the missing link in improving the health of Somali immigrant women in Oslo.

    Science.gov (United States)

    Gele, Abdi A; Pettersen, Kjell Sverre; Torheim, Liv Elin; Kumar, Bernadette

    2016-11-03

    Existing studies report a positive association between inadequate health literacy and immigrant's adverse health outcomes. Despite substantial research on this topic among immigrants, little is known about the level of health literacy among Somali women in Europe, and particularly in Norway. A cross sectional study using respondent driven sampling was conducted in Oslo, Norway. A sample of 302 Somali women, 25 years and older, was interviewed using the short version of the European Health Literacy Questionnaire. Data was analysed using logistic regression. Findings revealed that 71 % of Somali women in Oslo lack the ability to obtain, understand and act upon health information and services, and to make appropriate health decisions. Being unemployed (OR 3.66, CI 1.08-12.3) and socially less integrated (OR 8.17, CI 1.21-54.8) were independent predictors of an inadequate health literacy among Somali women. Enhanced health literacy will most likely increase the chance to better health outcomes for immigrants, thereby moving towards health equity in the Norwegian society. Therefore, policies and programs are required to focus and improve health literacy of immigrant communities.

  1. Phenotypic Characteristics of Autism Spectrum Disorder in a Diverse Sample of Somali and Other Children

    Science.gov (United States)

    Esler, Amy N.; Hall-Lande, Jennifer; Hewitt, Amy

    2017-01-01

    The potential for culture to impact diagnosis of autism spectrum disorder (ASD) is high, yet remains largely unstudied. This study examined differences across racial/ethnic groups in ASD symptoms, cognitive and adaptive skills, and related behaviors in children with ASD that included a unique subgroup, children from the Somali diaspora. Somali…

  2. Rethinking migration in the digital age : Transglocalization and the Somali diaspora

    NARCIS (Netherlands)

    Kok, S.; Rogers, R.

    2017-01-01

    In this study, we examine the transnational networks of the Somali diaspora online. We explore the claims that the web signifies a shift towards a de-territorialized, transnational diaspora, which constructs its identity and engagement around a transnational imagined community. Based on a network

  3. Working Together in a Deficit Logic: Home-School Partnerships with Somali Diaspora Parents

    Science.gov (United States)

    Matthiesen, Noomi Christine Linde

    2017-01-01

    Drawing on discursive psychology this article examines the understandings teachers and principals in Danish Public Schools have regarding Somali diaspora parenting practices. Furthermore, the article investigates what these understandings mean in interaction with children in the classrooms and with parents in home-school communication. It is…

  4. Beyond the playing field: experiences of sport, social capital and integration among Somalis in Australia

    NARCIS (Netherlands)

    Spaaij, R.

    2012-01-01

    This paper explores the role of recreational sport as a means and marker of social integration by analysing the lived experiences of Somali people from refugee backgrounds with sport. Drawing on a three-year multi-sided ethnography, the paper examines the extent to and ways in which participation in

  5. Health literacy: the missing link in improving the health of Somali immigrant women in Oslo

    Directory of Open Access Journals (Sweden)

    Abdi A. Gele

    2016-11-01

    Full Text Available Abstract Background Existing studies report a positive association between inadequate health literacy and immigrant’s adverse health outcomes. Despite substantial research on this topic among immigrants, little is known about the level of health literacy among Somali women in Europe, and particularly in Norway. Methods A cross sectional study using respondent driven sampling was conducted in Oslo, Norway. A sample of 302 Somali women, 25 years and older, was interviewed using the short version of the European Health Literacy Questionnaire. Data was analysed using logistic regression. Results Findings revealed that 71 % of Somali women in Oslo lack the ability to obtain, understand and act upon health information and services, and to make appropriate health decisions. Being unemployed (OR 3.66, CI 1.08–12.3 and socially less integrated (OR 8.17, CI 1.21–54.8 were independent predictors of an inadequate health literacy among Somali women. Conclusions Enhanced health literacy will most likely increase the chance to better health outcomes for immigrants, thereby moving towards health equity in the Norwegian society. Therefore, policies and programs are required to focus and improve health literacy of immigrant communities.

  6. Somali refugees' experiences with their general practitioners: frames of reference and critical episodes.

    NARCIS (Netherlands)

    Feldmann, C.T.; Bensing, J.M.; Ruijter, A. de; Boeije, H.R.

    2006-01-01

    The article presents the results of a qualitative study based on in-depth interviews with Somali refugees living in The Netherlands, on their experiences with general practitioners (GPs). The central question is: what are the frames of reference participants use to interpret their experiences? The

  7. Somali refugees’ experiences with their general practitioners: frames of reference and critical episodes

    NARCIS (Netherlands)

    Titia Feldmann, C.; Bensing, J.; Ruijter, Arie de; Boeije, H.R.

    2006-01-01

    The article presents the results of a qualitative study based on in-depth interviews with Somali refugees living in The Netherlands, on their experiences with general practitioners (GPs). The central question is: what are the frames of reference participants use to interpret their experiences? The

  8. Beyond Culture and Language: Access to Diabetes Preventive Health Services among Somali Women in Norway

    Directory of Open Access Journals (Sweden)

    Abdi A. Gele

    2015-01-01

    Full Text Available Despite the high prevalence of type 2 diabetes in some immigrant and refugee communities in Norway, there is very little information available on their utilization of diabetes prevention interventions, particularly for women from Somali immigrant communities. A qualitative study of 30 Somali immigrant women aged 25 years and over was carried out in the Oslo area. Unstructured interviews were used to explore women’s knowledge of diabetes, their access to preventive health facilities, and factors impeding their reception of preventive health programs targeted for the prevention of type 2 diabetes. The study participants were found to have a good knowledge of diabetes. They knew that a sedentary lifestyle and unhealthy diet are among the risk factors for diabetes. Regardless of their knowledge, participants reported a sedentary lifestyle accompanied with the consumption of an unhealthy diet. This was attributed to a lack of access to tailored physical activity services and poor access to health information. Considering gender-exclusive training facilities for Somali immigrant women and others with similar needs, in addition to access to tailored health information on diet, may encourage Somali women to adopt a healthy lifestyle, and it will definitely contribute to a national strategy for the prevention of diabetes.

  9. Winter monsoon circulation of the northern Arabian Sea and Somali Current

    Science.gov (United States)

    Schott, Friedrich A.; Fischer, Jürgen

    2000-03-01

    The winter monsoon circulation in the northern inflow region of the Somali Current is discussed on the basis of an array of moored acoustic Doppler current profiler and current meter stations deployed during 1995-1996 and a ship survey carried out in January 1998. It is found that the westward inflow into the Somali Current regime occurs essentially south of 11°N and that this inflow bifurcates at the Somali coast, with the southward branch supplying the equatorward Somali Current and the northward one returning into the northwestern Arabian Sea. This northward branch partially supplies a shallow outflow through the Socotra Passage between the African continent and the banks of Socotra and partially feeds into eastward recirculation directly along the southern slopes of Socotra. Underneath this shallow surface flow, southwestward undercurrent flows are observed. Undercurrent inflow from the Gulf of Aden through the Socotra Passage occurs between 100 and 1000 m, with its current core at 700-800 m, and is clearly marked by the Red Sea Water (RSW) salinity maximum. The observations suggest that the maximum RSW inflow out of the Gulf of Aden occurs during the winter monsoon season and uses the Socotra Passage as its main route into the Indian Ocean. Westward undercurrent inflow into the Somali Current regime is also observed south of Socotra, but this flow lacks the RSW salinity maximum. Off the Arabian peninsula, eastward boundary flow is observed in the upper 800 m with a compensating westward flow to the south. The observed circulation pattern is qualitatively compared with recent high-resolution numerical model studies and is found to be in basic agreement.

  10. How to kill creativity.

    Science.gov (United States)

    Amabile, T M

    1998-01-01

    In today's knowledge economy, creativity is more important than ever. But many companies unwittingly employ managerial practices that kill it. How? By crushing their employees' intrinsic motivation--the strong internal desire to do something based on interests and passions. Managers don't kill creativity on purpose. Yet in the pursuit of productivity, efficiency, and control--all worthy business imperatives--they undermine creativity. It doesn't have to be that way, says Teresa Amabile. Business imperatives can comfortably coexist with creativity. But managers will have to change their thinking first. Specifically, managers will need to understand that creativity has three parts: expertise, the ability to think flexibly and imaginatively, and motivation. Managers can influence the first two, but doing so is costly and slow. It would be far more effective to increase employees' intrinsic motivation. To that end, managers have five levers to pull: the amount of challenge they give employees, the degree of freedom they grant around process, the way they design work groups, the level of encouragement they give, and the nature of organizational support. Take challenge as an example. Intrinsic motivation is high when employees feel challenged but not overwhelmed by their work. The task for managers, therefore, becomes matching people to the right assignments. Consider also freedom. Intrinsic motivation--and thus creativity--soars when managers let people decide how to achieve goals, not what goals to achieve. Managers can make a difference when it comes to employee creativity. The result can be truly innovative companies in which creativity doesn't just survive but actually thrives.

  11. "A Somali girl is Muslim and does not have premarital sex. Is vaccination really necessary?" A qualitative study into the perceptions of Somali women in the Netherlands about the prevention of cervical cancer

    NARCIS (Netherlands)

    Salad, J.; Verdonk, P.; de Boer, F.; Abma, T.A.

    2015-01-01

    Introduction: Participation in Human Papillomavirus (HPV) vaccination and Papanicolaou Screening (Pap smears) is low among ethnic minorities in the Netherlands and hardly any information is available about the cervical cancer prevention methods of Somali women living in the diaspora. This

  12. Paleogene magnetic isochrons and palaeo-propagators in the Arabian and Eastern Somali basins, NW Indian Ocean

    Digital Repository Service at National Institute of Oceanography (India)

    Chaubey, A.K.; Dyment, J.; Bhattacharya, G.C.; Royer, J.-Y.; Srinivas, K.; Yatheesh, V.

    A revised magnetic isochron map of the conjugate Arabian and Eastern Somali basins based on an up-to-date compilation of Indian, French, and other available sea-surface magnetic data are presented. The magnetic anomaly and the modulus...

  13. Archivists Killed for Political Reasons

    NARCIS (Netherlands)

    de Baets, Antoon

    2015-01-01

    This essay, Archivists Killed for Political Reasons, offers an overview of archivists who were killed for political reasons through the ages. After determining the criteria for inclusion, sixteen such political murders of archivists are briefly discussed. These cases were distributed over six

  14. Consumption of healthy foods and associated socio-demographic factors among Russian, Somali and Kurdish immigrants in Finland.

    Science.gov (United States)

    Adebayo, Folasade A; Itkonen, Suvi T; Koponen, Päivikki; Prättälä, Ritva; Härkänen, Tommi; Lamberg-Allardt, Christel; Erkkola, Maijaliisa

    2017-05-01

    We evaluated the consumption of healthy foods among Russian, Somali and Kurdish immigrants in Finland, and examined the relationship between socio-demographic factors and food consumption. We used data from the Migrant Health and Wellbeing Study (Maamu), a population-based health interview and examination survey in six different municipalities in Finland between 2010 and 2012. Altogether, 635 men and 737 women, aged 18-64 years, of Russian ( n = 527), Somali ( n = 337) and Kurdish ( n = 508) origin were included. The important socio-demographic determinants of healthy food consumption - sex, age, education, place of residence and household size - were assessed by logistic regression. Based on the consumption frequencies of recommended healthy foods - fruits, berries, vegetables, fish and rye bread - immigrants of Russian origin had higher consumption of healthy foods than their peers of Kurdish and Somali origin. Low consumption of fresh vegetables, fruits and berries was found among Somali immigrants. Sex and age were the most important determinants of healthy food consumption, as women and older age groups had diets closer to the national nutrition recommendations. High educational level was also positively associated with healthy food consumption. We found ethnic differences in the consumption of healthy foods among the immigrant groups of Russian, Somali and Kurdish origin in Finland. Socio-demographic factors, especially age, sex and education, seem to also play an important role in immigrants' food consumption. Further studies examining the consumption of fruits, berries and fresh vegetables among Somali immigrants in Finland are needed.

  15. Sexual Health Care, Sexual Behaviors and Functioning, and Female Genital Cutting: Perspectives From Somali Women Living in the United States.

    Science.gov (United States)

    Connor, Jennifer Jo; Hunt, Shanda; Finsaas, Megan; Ciesinski, Amanda; Ahmed, Amira; Robinson, Beatrice Bean E

    2016-01-01

    We investigated the sexual values, attitudes, and behaviors of 30 Somali female refugees living in a large metropolitan area of Minnesota by collecting exploratory sexual health information based on the components of the sexual health model-components posited to be essential aspects of healthy human sexuality. A Somali-born bilingual interviewer conducted the semistructured interviews in English or Somali; 22 participants chose to be interviewed in Somali. Interviews were translated, transcribed, and analyzed using descriptive statistics and thematic analyses. Our study findings highlighted a sexually conservative culture that values sexual intimacy, female and male sexual pleasure, and privacy in marriage; vaginal sexual intercourse as the only sanctioned sexual behavior; and the importance of Islamic religion in guiding sexual practices. Findings related to human immunodeficiency virus (HIV) revealed HIV testing at immigration, mixed attitudes toward condom use, and moderate knowledge about HIV transmission modes. Female genital cutting (FGC) was a pervasive factor affecting sexual functioning in Somali women, with attitudes about the controversial practice in transition. We recommend that health professionals take the initiative to discuss sexual health care and safer sex, sexual behaviors/functioning, and likely challenges to sexual health with Somali women--as they may be unlikely to broach these subjects without permission and considerable encouragement.

  16. "The Killing Fields" of Innovation

    DEFF Research Database (Denmark)

    Ingerslev, Karen

    2014-01-01

    to clustering of ideas, a design strategy which seemed to kill unique ideas. The reframing of innovation as a radical endeavor killed learning from others for being not innovative. The findings of this paper supplement theories of deliberate killing of ideas by suggesting framing, design and facilitation......This paper points to seemingly contradicted processes of framing innovation, idea generation and killing ideas. It reports from a yearlong innovation project, where health care professionals explored problems and tested ideas for solutions, regarding a future downsizing of the case hospital....... Theories in various ways describe the opening and closing phases of innovation. Exploration and idea generation opens a field of interest, which is then closed by making choices of ideas to further explore in the next opening phase. These choices deliberately kill a lot of ideas. In the innovation project...

  17. Notes on super Killing tensors

    Energy Technology Data Exchange (ETDEWEB)

    Howe, P.S. [Department of Mathematics, King’s College London,The Strand, London WC2R 2LS (United Kingdom); Lindström, University [Department of Physics and Astronomy, Theoretical Physics, Uppsala University,SE-751 20 Uppsala (Sweden); Theoretical Physics, Imperial College London,Prince Consort Road, London SW7 2AZ (United Kingdom)

    2016-03-14

    The notion of a Killing tensor is generalised to a superspace setting. Conserved quantities associated with these are defined for superparticles and Poisson brackets are used to define a supersymmetric version of the even Schouten-Nijenhuis bracket. Superconformal Killing tensors in flat superspaces are studied for spacetime dimensions 3,4,5,6 and 10. These tensors are also presented in analytic superspaces and super-twistor spaces for 3,4 and 6 dimensions. Algebraic structures associated with superconformal Killing tensors are also briefly discussed.

  18. Screening for Posttraumatic Stress Disorder among Somali ex-combatants: A validation study

    Directory of Open Access Journals (Sweden)

    Rockstroh Brigitte

    2007-09-01

    Full Text Available Abstract Background In Somalia, a large number of active and former combatants are affected by psychological problems such as Posttraumatic Stress Disorder (PTSD. This disorder impairs their ability to re-integrate into civilian life. However, many screening instruments for Posttraumatic Stress Disorder used in post-conflict settings have limited validity. Here we report on development and validation of a screening tool for PTSD in Somali language with a sample of ex-combatants. Methods We adapted the Posttraumatic Diagnostic Scale (PDS to reflect linguistic and cultural differences within the Somali community so that local interviewers could be trained to administer the scale. For validation purposes, a randomly selected group of 135 Somali ex-combatants was screened by trained local interviewers; 64 of them were then re-assessed by trained clinical psychologists using the Composite International Diagnostic Interview (CIDI and the Self-Report Questionnaire (SRQ-20. Results The screening instrument showed good internal consistency (Cronbach's α = .86, convergent validity with the CIDI (sensitivity = .90; specificity = .90 as well as concurrent validity: positive cases showed higher SRQ-20 scores, higher prevalence of psychotic symptoms, and higher levels of intake of the local stimulant drug khat. Compared to a single cut-off score, the multi-criteria scoring, in keeping with the DSM-IV, produced more diagnostic specificity. Conclusion The results provide evidence that our screening instrument is a reliable and valid method to detect PTSD among Somali ex-combatants. A future Disarmament, Demobilization and Reintegration Program in Somalia is recommended to screen for PTSD in order to identify ex-combatants with special psycho-social needs.

  19. When female circumcision comes to the West: attitudes toward the practice among Somali Immigrants in Oslo.

    Science.gov (United States)

    Gele, Abdi A; Johansen, Elise B; Sundby, Johanne

    2012-08-27

    Female circumcision (FC) has lifelong adverse social and health consequences for women, and its abolition will not only enhance the health of children and women, but also promote gender equality. Like many other Western countries, Norway hosts a large proportion of immigrants from FC-practicing countries, though primarily from Somalia, which is the country with the highest prevalence of FC in the world. A behavioral change by the practicing communities has the best chance to successfully and sustainably eliminate this practice. However, FC prevention programs require a behavioral surveillance that monitors the process of change, with this being the first quantitative study since the major migration of the Somali community to Norway began in 1991 to investigate whether or not Somali immigrants' attitudes toward the practice has improved in favor of its abandonment. A cross-sectional study using a respondent-driven sampling (RDS) was conducted in Oslo from April to June of 2011. A sample of 214 persons was interviewed, using structured questionnaires. The results show that 70% of Somalis in Oslo support the discontinuation of all forms of FC compared to 30% who support its continuation, with the latter group more likely to be people who lived in Norway ≤ 4 years. Of the 10 girls who came to Norway at the age of ≤ 7 years, only one was circumcised, though whether the circumcision occurred before or after the girl's arrival in Norway remains unclear. The perception that FC is required by religion was the sole factor to be significantly associated with an ongoing support of FC. The study reveals that Somalis in Oslo demonstrate a trend to abandon this practice over time. Nevertheless, the 30% of the people who still support its continuation, and who are primarily newly arrived immigrants, require a targeted intervention that is implemented in the early phase of the immigrants' arrival.

  20. Validation of a home food inventory among low-income Spanish- and Somali-speaking families.

    Science.gov (United States)

    Hearst, Mary O; Fulkerson, Jayne A; Parke, Michelle; Martin, Lauren

    2013-07-01

    To refine and validate an existing home food inventory (HFI) for low-income Somali- and Spanish-speaking families. Formative assessment was conducted using two focus groups, followed by revisions of the HFI, translation of written materials and instrument validation in participants’ homes. Twin Cities Metropolitan Area, Minnesota, USA. Thirty low-income families with children of pre-school age (fifteen Spanish-speaking; fifteen Somali-speaking) completed the HFI simultaneously with, but independently of, a trained staff member. Analysis consisted of calculation of both item-specific and average food group kappa coefficients, specificity, sensitivity and Spearman’s correlation between participants’ and staff scores as a means of assessing criterion validity of individual items, food categories and the obesogenic score. The formative assessment revealed the need for few changes/additions for food items typically found in Spanish-speaking households. Somali-speaking participants requested few additions, but many deletions, including frozen processed food items, non-perishable produce and many sweets as they were not typical food items kept in the home. Generally, all validity indices were within an acceptable range, with the exception of values associated with items such as ‘whole wheat bread’ (k = 0.16). The obesogenic score (presence of high-fat, high-energy foods) had high criterion validity with k = 0.57, sensitivity = 91.8%, specificity = 70.6% and Spearman correlation = 0.78. The revised HFI is a valid assessment tool for use among Spanish and Somali households. This instrument refinement and validation process can be replicated with other population groups.

  1. Migration experiences, employment status and psychological distress among Somali immigrants: a mixed-method international study.

    Science.gov (United States)

    Warfa, Nasir; Curtis, Sarah; Watters, Charles; Carswell, Ken; Ingleby, David; Bhui, Kamaldeep

    2012-09-07

    The discourse about mental health problems among migrants and refugees tends to focus on adverse pre-migration experiences; there is less investigation of the environmental conditions in which refugee migrants live, and the contrasts between these situations in different countries. This cross-national study of two samples of Somali refugees living in London (UK) and Minneapolis, Minnesota, (USA) helps to fill a gap in the literature, and is unusual in being able to compare information collected in the same way in two cities in different countries. There were two parts to the study, focus groups to gather in-depth qualitative data and a survey of health status and quantifiable demographic and material factors. Three of the focus groups involved nineteen Somali professionals and five groups included twenty-eight lay Somalis who were living in London and Minneapolis. The quantitative survey was done with 189 Somali respondents, also living in London and Minneapolis. We used the MINI International Neuropsychiatric Interview (MINI) to assess ICD-10 and DSM-IV mental disorders. The overall qualitative and quantitative results suggested that challenges to masculinity, thwarted aspirations, devalued refugee identity, unemployment, legal uncertainties and longer duration of stay in the host country account for poor psychological well-being and psychiatric disorders among this group. The use of a mixed-methods approach in this international study was essential since the quantitative and qualitative data provide different layers and depth of meaning and complement each other to provide a fuller picture of complex and multi-faceted life situations of refugees and asylum seekers. The comparison between the UK and US suggests that greater flexibility of access to labour markets for this refugee group might help to promote opportunities for better integration and mental well-being.

  2. Production systems and reproductive performances of Camelus dromedarius in Somali regional state, eastern Ethiopia

    Directory of Open Access Journals (Sweden)

    Simenew Keskes

    2013-12-01

    Full Text Available Across-sectional questionnaire survey and focused group discussions were conducted to characterize camel production systems and to evaluate reproductive performances of camels at their natural pastoralist management systems of Somali region. A total of 100 households were included in the study during the period of October 2012 to March 2013. About 98% of Somali pastoralists preferred camels as their first choice over other livestock species and mainly kept in the society for milk and meat production. The camel management dominating in the study areas of Somali region is traditional nomadic. Camel is one of the most important livestock for Somali pastoralists’ livelihood as a source of milk, meat and draught power. Mature female camels were dominant (54.87% in the camel herd. The ratio of male to female camel was 1:13. Mean age at first calving and calving interval were 62.16±10.44 and 23.28±3.36 months respectively. Age at first calving and calving interval can be minimized to 57±5.52 and 21.84±4.8 months by proper husbandry and health care. The mean lactation length was 11.51±1.91 months. Diseases and predators were reported as the main causes of calf mortality. In the herd dynamic simulation calf mortality rate can be reduced at least to 7% only by preventing predators attack. Diseases (66%, lack of pasture (59% and security (47% were the main constraints in camel production of the study areas. For the better productivity of camels, the major constraints such as disease problems, lack of pasture and tribal conflicts should be mitigated. Proper husbandry and health services can play significant roles in the long term improvement of camel production and productivity of the region.  

  3. Migration experiences, employment status and psychological distress among Somali immigrants: a mixed-method international study

    Directory of Open Access Journals (Sweden)

    Warfa Nasir

    2012-09-01

    Full Text Available Abstract Background The discourse about mental health problems among migrants and refugees tends to focus on adverse pre-migration experiences; there is less investigation of the environmental conditions in which refugee migrants live, and the contrasts between these situations in different countries. This cross-national study of two samples of Somali refugees living in London (UK and Minneapolis, Minnesota, (USA helps to fill a gap in the literature, and is unusual in being able to compare information collected in the same way in two cities in different countries. Methods There were two parts to the study, focus groups to gather in-depth qualitative data and a survey of health status and quantifiable demographic and material factors. Three of the focus groups involved nineteen Somali professionals and five groups included twenty-eight lay Somalis who were living in London and Minneapolis. The quantitative survey was done with 189 Somali respondents, also living in London and Minneapolis. We used the MINI International Neuropsychiatric Interview (MINI to assess ICD-10 and DSM-IV mental disorders. Results The overall qualitative and quantitative results suggested that challenges to masculinity, thwarted aspirations, devalued refugee identity, unemployment, legal uncertainties and longer duration of stay in the host country account for poor psychological well-being and psychiatric disorders among this group. Conclusion The use of a mixed-methods approach in this international study was essential since the quantitative and qualitative data provide different layers and depth of meaning and complement each other to provide a fuller picture of complex and multi-faceted life situations of refugees and asylum seekers. The comparison between the UK and US suggests that greater flexibility of access to labour markets for this refugee group might help to promote opportunities for better integration and mental well-being.

  4. When female circumcision comes to the West: Attitudes toward the practice among Somali Immigrants in Oslo

    Directory of Open Access Journals (Sweden)

    Gele Abdi A

    2012-08-01

    Full Text Available Abstract Background Female circumcision (FC has lifelong adverse social and health consequences for women, and its abolition will not only enhance the health of children and women, but also promote gender equality. Like many other Western countries, Norway hosts a large proportion of immigrants from FC-practicing countries, though primarily from Somalia, which is the country with the highest prevalence of FC in the world. A behavioral change by the practicing communities has the best chance to successfully and sustainably eliminate this practice. However, FC prevention programs require a behavioral surveillance that monitors the process of change, with this being the first quantitative study since the major migration of the Somali community to Norway began in 1991 to investigate whether or not Somali immigrants’ attitudes toward the practice has improved in favor of its abandonment. Methods A cross-sectional study using a respondent-driven sampling (RDS was conducted in Oslo from April to June of 2011. A sample of 214 persons was interviewed, using structured questionnaires. Results The results show that 70% of Somalis in Oslo support the discontinuation of all forms of FC compared to 30% who support its continuation, with the latter group more likely to be people who lived in Norway ≤ 4 years. Of the 10 girls who came to Norway at the age of ≤ 7 years, only one was circumcised, though whether the circumcision occurred before or after the girl’s arrival in Norway remains unclear. The perception that FC is required by religion was the sole factor to be significantly associated with an ongoing support of FC. Conclusion The study reveals that Somalis in Oslo demonstrate a trend to abandon this practice over time. Nevertheless, the 30% of the people who still support its continuation, and who are primarily newly arrived immigrants, require a targeted intervention that is implemented in the early phase of the immigrants’ arrival.

  5. Khat use, PTSD and psychotic symptoms among Somali refugees in Nairobi - a pilot study

    Directory of Open Access Journals (Sweden)

    Marina eWidmann

    2014-06-01

    Full Text Available In East-African and Arab countries, khat leaves are traditionally chewed in social settings. They contain the amphetamine-like alkaloid cathinone. Especially among Somali refugees khat use has been associated with psychiatric symptoms. We assessed khat use patterns and psychiatric symptoms among male Somali refugees living in a disadvantaged urban settlement area in Kenya, a large group that has not yet received scientific attention. We wanted to explore consume patterns and study the associations between khat use, traumatic experiences and psychotic symptoms.Using privileged access sampling we recruited 33 healthy male khat chewers and 15 comparable non-chewers. Based on extensive preparatory work, we assessed khat use, khat dependence according to DSM-IV, traumatic experiences, Posttraumatic Stress Disorder and psychotic symptoms using standardized diagnostic instruments that had been adapted to the Somali language and culture.Hazardous use patterns like chewing for more than 24 hours without interruption were frequently reported. All khat users fulfilled the DSM-IV-criteria for dependence and eighty-five percent reported functional khat-use, i.e. that khat helps them to forget painful experiences. We found that the studied group was heavily burdened by traumatic events and posttraumatic symptoms. Khat users had experienced more traumatic events and had more often PTSD than non-users. Most khat users experience khat-related psychotic symptoms and in a quarter of them we found true psychotic symptoms. In contrast, among control group members no psychotic symptoms could be detected.We found first evidence for the existence and high prevalence of severely hazardous use patterns, comorbid psychiatric symptoms and khat use as a self-medication of trauma-consequences among male Somali refugees in urban Kenyan refugee settlements. There is a high burden by psychopathology and adequate community-based interventions urgently need to be developed.

  6. The role of potential vorticity anomalies in the Somali Jet on Indian Summer Monsoon Intraseasonal Variability

    Science.gov (United States)

    Rai, P.; Joshi, M.; Dimri, A. P.; Turner, A. G.

    2018-06-01

    The climate of the Indian subcontinent is dominated by rainfall arising from the Indian summer monsoon (ISM) during June to September. Intraseasonal variability during the monsoon is characterized by periods of heavy rainfall interspersed by drier periods, known as active and break events respectively. Understanding and predicting such events is of vital importance for forecasting human impacts such as water resources. The Somali Jet is a key regional feature of the monsoon circulation. In the present study, we find that the spatial structure of Somali Jet potential vorticity (PV) anomalies varies considerably during active and break periods. Analysis of these anomalies shows a mechanism whereby sea surface temperature (SST) anomalies propagate north/northwestwards through the Arabian Sea, caused by a positive feedback loop joining anomalies in SST, convection, modification of PV by diabatic heating and mixing in the atmospheric boundary layer, wind-stress curl, and ocean upwelling processes. The feedback mechanism is consistent with observed variability in the coupled ocean-atmosphere system on timescales of approximately 20 days. This research suggests that better understanding and prediction of monsoon intraseasonal variability in the South Asian monsoon may be gained by analysis of the day-to-day dynamical evolution of PV in the Somali Jet.

  7. Ancient DNA from Nubian and Somali wild ass provides insights into donkey ancestry and domestication.

    Science.gov (United States)

    Kimura, Birgitta; Marshall, Fiona B; Chen, Shanyuan; Rosenbom, Sónia; Moehlman, Patricia D; Tuross, Noreen; Sabin, Richard C; Peters, Joris; Barich, Barbara; Yohannes, Hagos; Kebede, Fanuel; Teclai, Redae; Beja-Pereira, Albano; Mulligan, Connie J

    2011-01-07

    Genetic data from extant donkeys (Equus asinus) have revealed two distinct mitochondrial DNA haplogroups, suggestive of two separate domestication events in northeast Africa about 5000 years ago. Without distinct phylogeographic structure in domestic donkey haplogroups and with little information on the genetic makeup of the ancestral African wild ass, however, it has been difficult to identify wild ancestors and geographical origins for the domestic mitochondrial clades. Our analysis of ancient archaeological and historic museum samples provides the first genetic information on the historic Nubian wild ass (Equus africanus africanus), Somali wild ass (Equus africanus somaliensis) and ancient donkey. The results demonstrate that the Nubian wild ass was an ancestor of the first donkey haplogroup. In contrast, the Somali wild ass has considerable mitochondrial divergence from the Nubian wild ass and domestic donkeys. These findings resolve the long-standing issue of the role of the Nubian wild ass in the domestication of the donkey, but raise new questions regarding the second ancestor for the donkey. Our results illustrate the complexity of animal domestication, and have conservation implications for critically endangered Nubian and Somali wild ass.

  8. De nasleep van Somalië, Rwanda en Srebrenica: overeenkomsten en verschillen

    Directory of Open Access Journals (Sweden)

    Thijs Brocades Zaalberg

    2010-01-01

    Full Text Available Klep, Christ, Somalië, Rwanda, Srebrenica. De nasleep van drie ontspoorde vredesmissies (Dissertatie Utrecht 2008; Amsterdam: Boom, 2008, 385 blz., ISBN 978 90 8506 668 2The Aftermath of Somalia, Rwanda and Srebrenica: Parallels and DifferencesChrist Klep has written an impressive and highly accessible thesis on the aftermath of three unsuccessful peace operations. By using a bold comparative approach and an ambitious tone of enquiry he places the traumatic Dutch Srebrenica experience in the context of two broadly similar processes of finger-pointing and evading responsibility in Canada and Belgium following their respective interventions in Somalia and Rwanda. He thus exposes many fascinating parallels, yet the historian Klep pays little attention to the differences between his case studies. This is regrettable, as this would have strengthened rather than weakened his otherwise compelling argument. The Somali case in particular differs from ‘Srebrenica’ and ‘Rwanda’, since the murders perpetrated by Canadian soldiers – horrific as they may have been – and the subsequent cover-up in no way constituted a defining moment in the collapsing international mission as a whole. Unlike the genocides in Rwanda and Srebrenica the death of the two Somalis was the result of a purely national Canadian failure, which helps explain why the Somalia Inquiry could identify guilty compatriots far more decisively than, for example, the Netherlands Institute for War Documentation (NIOD in its Srebrenica report.

  9. The role of potential vorticity anomalies in the Somali Jet on Indian Summer Monsoon Intraseasonal Variability

    Science.gov (United States)

    Rai, P.; Joshi, M.; Dimri, A. P.; Turner, A. G.

    2017-08-01

    The climate of the Indian subcontinent is dominated by rainfall arising from the Indian summer monsoon (ISM) during June to September. Intraseasonal variability during the monsoon is characterized by periods of heavy rainfall interspersed by drier periods, known as active and break events respectively. Understanding and predicting such events is of vital importance for forecasting human impacts such as water resources. The Somali Jet is a key regional feature of the monsoon circulation. In the present study, we find that the spatial structure of Somali Jet potential vorticity (PV) anomalies varies considerably during active and break periods. Analysis of these anomalies shows a mechanism whereby sea surface temperature (SST) anomalies propagate north/northwestwards through the Arabian Sea, caused by a positive feedback loop joining anomalies in SST, convection, modification of PV by diabatic heating and mixing in the atmospheric boundary layer, wind-stress curl, and ocean upwelling processes. The feedback mechanism is consistent with observed variability in the coupled ocean-atmosphere system on timescales of approximately 20 days. This research suggests that better understanding and prediction of monsoon intraseasonal variability in the South Asian monsoon may be gained by analysis of the day-to-day dynamical evolution of PV in the Somali Jet.

  10. Killing Horizons as Equipotential Hypersurfaces

    OpenAIRE

    Smolić, Ivica

    2012-01-01

    In this note we present a new proof that Killing horizons are equipotential hypersurfaces for the electric and the magnetic scalar potential, that makes no use of gravitational field equations or the assumption about the existence of bifurcation surface.

  11. Somali Parents' Experiences of Bringing up Children in Finland: Exploring Social-Cultural Change within Migrant Households

    Directory of Open Access Journals (Sweden)

    Filio Degni

    2006-05-01

    Full Text Available Approximately 5,000 to 6,000 Somalis arrived in Finland between 1990 and 1995 through Russia. Currently, 8,096 have settled permanently in the country. The data reported here is from a 1998-1999 research survey carried out in the Finish cities of Helsinki and Turku. The survey of 117 married Somalis explored the social-cultural determinants of contraception use. The paper presented here focuses upon one particular aspect of the survey. We selected 21 Somali parents (11 women and 10 men to look in-depth at the experiences of Somali migrants raising children in Finland. All of the respondents selected have more than 5 children in their family and all were asked to describe their experiences of raising children in Finland and, more generally, in establishing and maintaining family structures. Unlike their experiences in Somali, bringing up large families (by Westerns standards is not a collective matter in Finland where biological parents are left to manage the family for themselves. A number of challenges also accompany this shift in family norms: first, and most notably, there is the need to re-establish control over one's life in an alien environment; second, intergenerational conflict between adult migrants and their adolescent children is often heightened. The findings indicate that Somalis' experiences of raising children in Finland raise important parenting challenges associated with changing generational, gender and family relations within the migrant household. Importantly, this case study of large Somali families shows how migrants' lives are intricately linked to the household dynamic between home and host country. URN: urn:nbn:de:0114-fqs060388

  12. Phantom metrics with Killing spinors

    Directory of Open Access Journals (Sweden)

    W.A. Sabra

    2015-11-01

    Full Text Available We study metric solutions of Einstein–anti-Maxwell theory admitting Killing spinors. The analogue of the IWP metric which admits a space-like Killing vector is found and is expressed in terms of a complex function satisfying the wave equation in flat (2+1-dimensional space–time. As examples, electric and magnetic Kasner spaces are constructed by allowing the solution to depend only on the time coordinate. Euclidean solutions are also presented.

  13. Spacetimes foliated by Killing horizons

    International Nuclear Information System (INIS)

    Pawlowski, Tomasz; Lewandowski, Jerzy; Jezierski, Jacek

    2004-01-01

    It seems to be expected that a horizon of a quasi-local type, such as a Killing or an isolated horizon, by analogy with a globally defined event horizon, should be unique in some open neighbourhood in the spacetime, provided the vacuum Einstein or the Einstein-Maxwell equations are satisfied. The aim of our paper is to verify whether that intuition is correct. If one can extend a so-called Kundt metric, in such a way that its null, shear-free surfaces have spherical spacetime sections, the resulting spacetime is foliated by so-called non-expanding horizons. The obstacle is Kundt's constraint induced at the surfaces by the Einstein or the Einstein-Maxwell equations, and the requirement that a solution be globally defined on the sphere. We derived a transformation (reflection) that creates a solution to Kundt's constraint out of data defining an extremal isolated horizon. Using that transformation, we derived a class of exact solutions to the Einstein or Einstein-Maxwell equations of very special properties. Each spacetime we construct is foliated by a family of the Killing horizons. Moreover, it admits another, transversal Killing horizon. The intrinsic and extrinsic geometries of the transversal Killing horizon coincide with the one defined on the event horizon of the extremal Kerr-Newman solution. However, the Killing horizon in our example admits yet another Killing vector tangent to and null at it. The geometries of the leaves are given by the reflection

  14. Attitudes towards and perceptions about contraceptive use among married refugee women of Somali descent living in Finland.

    Science.gov (United States)

    Degni, F; Koivusilta, L; Ojanlatva, A

    2006-09-01

    To assess attitudes towards and perceptions about contraceptive use among married refugee women of Somali descent living in Finland. A sample of 100 married refugee women of Somali descent (18-50 years of age) were invited to participate in a study on contraceptive use in Finland (30 women refused). Qualitative and quantitative methods were used to collect the data. Questionnaire of the first data set was written in the Somali language. Interviews were conducted in the Somali language. The attitudes and opinions of these women towards contraceptive use (73% did not use contraceptives, 27% did use them) were connected with religious beliefs and issues involving marital relations. Religious or gender issues did not seem to influence those who used contraception. The findings indicated that the majority of the married refugee women of Somali descent living in Finland did not use contraception. The process of starting the use of contraception was possible because of an access to good reproductive health care and family planning services, changes in life situations, and adaptations to Finnish social and cultural norms.

  15. Trauma, poverty and mental health among Somali and Rwandese refugees living in an African refugee settlement – an epidemiological study

    Directory of Open Access Journals (Sweden)

    Ertl Verena

    2009-05-01

    Full Text Available Abstract Background The aim of this study was to establish the prevalence of posttraumatic stress disorder (PTSD and depression among Rwandese and Somali refugees resident in a Ugandan refugee settlement, as a measure of the mental health consequences of armed conflict, as well as to inform a subsequent mental health outreach program. The study population comprised a sample from 14400 (n = 519 Somali and n = 906 Rwandese refugees resident in Nakivale refugee settlement in South Western Uganda during the year 2003. Methods The Posttraumatic Diagnostic Scale (PDS and the Hopkins Symptom Checklist 25 were used to screen for posttraumatic stress disorder and depression. Results Thirty two percent of the Rwandese and 48.1% of the Somali refugees were found to suffer from PTSD. The Somalis refugees had a mean of 11.95 (SD = 6.17 separate traumatic event types while the Rwandese had 8.86 (SD = 5.05. The Somalis scored a mean sum score of 21.17 (SD = 16.19 on the PDS while the Rwandese had a mean sum score of 10.05 (SD = 9.7. Conclusion Mental health consequences of conflict remain long after the events are over, and therefore mental health intervention is as urgent for post-conflict migrant populations as physical health and other emergency interventions. A mental health outreach program was initiated based on this study.

  16. Killing, letting die and euthanasia.

    Science.gov (United States)

    Husak, D N

    1979-12-01

    Medical ethicists debate whether or not the moral assessment of cases of euthanasia should depend on whether the patient is 'killed' or 'allowed to die'. The usual presupposition is that a clear distinction between killing and letting die can be drawn so that this substantive question is not begged. I contend that the categorisation of cases of instances of killing rather than as instances of letting die depends in part on a prior moral assessment of the case. Hence is it trivially rather than substantively true that the distinction has moral significance. But even if a morally neutral (ie non-question begging) distinction could be drawn, its application to the euthanasia controversy is problematic. I illustrate the difficulties of employing this distinction to reach moral conclusions by critically discussing Philippa Foot's recent treatment of euthanasia. I conclude that even if an act of euthanasia is an instance of killing, and there exists a prima facie moral duty not to kill, and no more stringent duty overrides this duty, one still cannot determine such an act to be morally impermissible.

  17. Killing, letting die and euthanasia.

    Science.gov (United States)

    Husak, D N

    1979-01-01

    Medical ethicists debate whether or not the moral assessment of cases of euthanasia should depend on whether the patient is 'killed' or 'allowed to die'. The usual presupposition is that a clear distinction between killing and letting die can be drawn so that this substantive question is not begged. I contend that the categorisation of cases of instances of killing rather than as instances of letting die depends in part on a prior moral assessment of the case. Hence is it trivially rather than substantively true that the distinction has moral significance. But even if a morally neutral (ie non-question begging) distinction could be drawn, its application to the euthanasia controversy is problematic. I illustrate the difficulties of employing this distinction to reach moral conclusions by critically discussing Philippa Foot's recent treatment of euthanasia. I conclude that even if an act of euthanasia is an instance of killing, and there exists a prima facie moral duty not to kill, and no more stringent duty overrides this duty, one still cannot determine such an act to be morally impermissible. PMID:541821

  18. "Guns do not kill, people do!"

    DEFF Research Database (Denmark)

    Lemche, Niels Peter

    2011-01-01

    The Bible does not kill, but many people who have read the Bible (in their way) have killed, virtually or in real.......The Bible does not kill, but many people who have read the Bible (in their way) have killed, virtually or in real....

  19. Vom Out-Law zum In-Law: Piraterie, Recht und Familie in Pirates of the CaribbeanCurrent Problems of Gypsy Studies

    OpenAIRE

    Irmtraud Hnilica

    2011-01-01

    In order to analyse the relationship between piracy, law and family, the article takes a look at thepopular Pirates of the Caribbean films. Hollywood turns out to link piracy with family; instead offorming the usually assumed contrast, both are closely intertwined entities. The film series cantherefore be seen as an unorthodox revision of the pirate’s common juridical classification as theanti-social hostis humani generis. It becomes apparent that, surprisingly, family sometimes maydevelop fr...

  20. Mental and somatic health and pre- and post-migration factors among older Somali refugees in Finland.

    Science.gov (United States)

    Mölsä, Mulki; Punamäki, Raija-Leena; Saarni, Samuli I; Tiilikainen, Marja; Kuittinen, Saija; Honkasalo, Marja-Liisa

    2014-08-01

    Mental and somatic health was compared between older Somali refugees and their pair-matched Finnish natives, and the role of pre-migration trauma and post-migration stressors among the refugees. One hundred and twenty-eight Somalis between 50-80 years of age were selected from the Somali older adult population living in the Helsinki area (N = 307). Participants were matched with native Finns by gender, age, education, and civic status. The BDI-21 was used for depressive symptoms, the GHQ-12 for psychological distress, and the HRQoL was used for health-related quality of life. Standard instruments were used for sleeping difficulties, somatic symptoms and somatization, hypochondria, and self-rated health. Clinically significant differences in psychological distress, depressive symptoms, sleeping difficulties, self-rated health status, subjective quality of life, and functional capacity were found between the Somali and Finnish groups. In each case, the Somalis fared worse than the Finns. No significant differences in somatization were found between the two groups. Exposure to traumatic events prior to immigrating to Finland was associated with higher levels of mental distress, as well as poorer health status, health-related quality of life, and subjective quality of life among Somalis. Refugee-related traumatic experiences may constitute a long lasting mental health burden among older adults. Health care professionals in host countries must take into account these realities while planning for the care of refugee populations. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  1. Assessment of source of information for polio supplementary immunization activities in 2014 and 2015, Somali, Ethiopia.

    Science.gov (United States)

    Bedada, Selamawit Yilma; Gallagher, Kathleen; Aregay, Aron Kassahun; Mohammed, Bashir; Maalin, Mohammed Adem; Hassen, Hassen Abdisemed; Ali, Yusuf Mohammed; Braka, Fiona; Kilebou, Pierre M'pele

    2017-01-01

    Communication is key for the successful implementation of polio vaccination campaigns. The purpose of this study is to review and analyse the sources of information utilized by caregivers during polio supplementary immunization activities (SIAs) in Somali, Ethiopia in 2014 and 2015. Data on sources of information about the polio campaign were collected post campaign from caregivers by trained data collectors as part of house to house independent monitoring. The sources of information analysed in this paper include town criers (via megaphones), health workers, religious leaders, kebele leaders (Kebele is the lowest administrative structure in Ethiopia), radio, television, text message and others. The repetition of these sources of information was analysed across years and zones for trends. Polio vaccination campaign coverage was also reviewed by year and zones within the Somali region in parallel with the major sources of information used in the respective year and zones. 57,745 responses were used for this analysis but the responses were received from polio SIAs. Zonal trends in using town criers as a major source of information in both study years remained consistent except in two zones. 87.5% of zones that reported at least 90% coverage during both study years had utilized town criers as a major source of information while the rest (12.5%) used health workers. We found that town criers were consistently the major source of information about the polio campaigns for Somali region parents and caregivers during polio immunization days held in 2014 and 2015. Health workers and kebele leaders were also important sources of information about the polio campaign for parents.

  2. political killings in South Africa

    African Journals Online (AJOL)

    mainly occurred in KwaZulu-Natal, with a much smaller number occurring in Mpumalanga and ... Though the problem is concentrated in specific provinces it is likely to impact on political life ... killings that are the focus of the article, including.

  3. To kill a mockingbird robot

    NARCIS (Netherlands)

    Bartneck, C.; Verbunt, M.N.C.; Mubin, O.; Al Mahmud, A.

    2007-01-01

    Robots are being introduced in our society but their social status is still unclear. A critical issue is if the robot's exhibition of intelligent life-like behavior leads to the users' perception of animacy. The ultimate test for the life-likeness of a robot is to kill it. We therefore conducted an

  4. Killing horizons as equipotential hypersurfaces

    International Nuclear Information System (INIS)

    Smolić, Ivica

    2012-01-01

    In this note we present a new proof that Killing horizons are equipotential hypersurfaces for the electric and the magnetic scalar potential, which makes no use of gravitational field equations or the assumption about the existence of a bifurcation surface. (note)

  5. Neogene oceanographic variations recorded in manganese nodules from the Somali Basin

    Digital Repository Service at National Institute of Oceanography (India)

    Banakar, V.K.; Nair, R.R.; Tarkian, M.; Haake, B.

    ), their application in interpreting the palaeoceanographic evolution of nodules has been relatively rare (see Segl et al., 1989; Mangini et al., 1990; Hein et al., 1992). In this paper we attempt to reconstruct the palaeocea- nographic history of a nodule from... the Somali Basin and correlate this history with the history inferred from the nearest DSDP Site. Material and methods The two manganese nodules studied here were collected using a free fall grab from a station (10D) located at 6°S and 52°E...

  6. Determinants of institutional delivery service utilization among pastorals of Liben Zone, Somali Regional State, Ethiopia, 2015

    Directory of Open Access Journals (Sweden)

    Zepro NB

    2016-12-01

    Full Text Available Nejimu Biza Zepro,1 Ahmed Tahir Ahmed2 1College of Health Sciences, Samara University, Samara, Afar, Ethiopia; 2College of Health Science, Jigjiga University, Jigjiga, Somali, Ethiopia Abstract: Maternal health service utilizations are poorly equipped, inaccessible, negligible, and not well documented in the pastoral society. This research describes a quantitative and qualitative study on the determinants of institutional delivery among pastoralists of Liben Zone with special emphasis on Filtu and Deka Suftu woredas of Somali Region, Ethiopia. The study was funded by the project “Fostering health care for refugees and pastoral communities in Somali Region, Ethiopia”. This community-based cross-sectional study was conducted during November 2015. Interviews through a questionnaire and focus group discussions were used to collect the data. Proportional to size allocation followed by systematic sampling technique was used to identify the study units. The major determinants of institutional delivery in the study area were as follows: being apparently healthy, lack of knowledge, long waiting time, poor quality services, cultural beliefs, religious misconception, partner decision, and long travel. Around one-third (133, 34.5% of the women had visited at least once for their pregnancy. More than half (78, 58.6% of the women had visited health facilities due to health problems and only 27 (19.9% women had attended the recommended four antenatal care visits. Majority (268, 69.6% of the pregnant women preferred to give birth at home. Women who attended antenatal care were two times more likely to deliver at health facilities (AOR, 95% confidence interval [CI] =2.38, 1.065–4.96. Women whose family members preferred health facilities had 14 times more probability to give birth in health institutions (AOR, 95% CI =13.79, 5.28–35.8. Women living in proximity to a health facility were 13 times more likely to give birth at health facilities than women

  7. Paleogene plate tectonic evolution of the Arabian and Eastern Somali basins

    Digital Repository Service at National Institute of Oceanography (India)

    Royer, J.-Y.; Chaubey, A.K.; Dyment, J.; Bhattacharya, G.C.; Srinivas, K.; Yatheesh, V.; Ramprasad, T.

    with systemahyphenminus tic ridge propagation in both basins (Miles & Roest 1993: Chaubey er at. 1998. Dyment 1998). Ridge propagation explains the large spreading asymmetry between the Arabian and Eastern Somali basins. Between Chrons 26 and 25. c. 65% of the crust..., the differences be- tween the India-Somalia and Capricorn-Somalia motions in Paleogene time can be used to estimate and refine the Capricorn-India integral motion as suggested by Royer & Chang (1991). Such en- deavour would require an accurate assessment...

  8. Communication and US-Somali Immigrant Human Papillomavirus (HPV) Vaccine Decision-Making.

    Science.gov (United States)

    Dailey, Phokeng M; Krieger, Janice L

    2017-09-01

    The current study uses a multiple goal theoretical perspective to explore how Somali immigrant families living in Ohio, USA, make decisions regarding whether to vaccinate their children against human papillomavirus (HPV)-a leading cause of cervical cancer. A focus was placed on the communication goals of parents in HPV vaccine discussions with their child and health care provider. Semi-structured interviews were audiotaped, transcribed, and analyzed using a grounded theory approach. Key themes are the implications of the vaccine for early sexual activity, confusion between HPV and HIV (human immunodeficiency virus), the perception that the HPV vaccine is unnecessary, uncertainty about the vaccine's efficacy and side effects, avoidance of parent-child communication about the vaccine, and a preference for framing the vaccine as a health promotion behavior. Framing the threat of HPV in the context of initiation of sexual activity, uncertainty regarding vaccine efficacy, and anticipated regret account for the inconsistency in HPV vaccine uptake among Somali parents. Clinicians should consider talking about HPV as a distal versus an immediate threat and HPV vaccine uptake as a health-promotion behavior rather than a sexually transmitted infection prevention behavior.

  9. Mental health of Somali adolescent refugees: the role of trauma, stress, and perceived discrimination.

    Science.gov (United States)

    Ellis, B Heidi; MacDonald, Helen Z; Lincoln, Alisa K; Cabral, Howard J

    2008-04-01

    The primary purpose of this study was to examine relations between trauma exposure, post-resettlement stressors, perceived discrimination, and mental health symptoms in Somali adolescent refugees resettled in the U.S. Participants were English-speaking Somali adolescent refugees between the ages of 11 and 20 (N = 135) who had resettled in the U.S. Participants were administered an interview battery comprising self-report instruments that included the UCLA Posttraumatic Stress Disorder (PTSD) Index, the War Trauma Screening Scale, the Every Day Discrimination scale, the Adolescent Post-War Adversities Scale, and the Acculturative Hassles Inventory. Results indicated that cumulative trauma was related to PTSD and depression symptoms. Further, post-resettlement stressors, acculturative stressors, and perceived discrimination were also associated with greater PTSD symptoms after accounting for trauma, demographic, and immigration variables. Number of years since resettlement in the US and perceived discrimination were significantly related to depressive symptoms, after accounting for trauma, demographic, and immigration variables. Further research elucidating the relations between post-resettlement stressors, discrimination, and mental health of refugee adolescents may inform intervention development. PsycINFO Database Record (c) 2008 APA, all rights reserved.

  10. WOMEN'S RIGHTS VIOLATION: HONOUR KILLINGS

    Directory of Open Access Journals (Sweden)

    CRISTINA OTOVESCU FRASIE

    2011-04-01

    Full Text Available In this study I have presented the domestic violence concept and the situation regarding the observing of woman’s rights in Syria. We have also evidenced the juridical aspects regarding the honor killing directed against women after the modification of the article 548 from the Penal Code changed by the President al-Asad on July the 1st 2009. The data offered by NGOs have been of great help for the elaboration of the study as also the statistic data presented in Thara E-Magazine regarding the cities where had been done the honor killings and their number, the instrument of the murder, the age of the victim, and the motives for the murders. It must be noticed that, lately, the Government fought for the observing of the woman’s rights and promoted he gender equality by appointing women in leading positions, including the vice-president one.

  11. Evolution equations for Killing fields

    International Nuclear Information System (INIS)

    Coll, B.

    1977-01-01

    The problem of finding necessary and sufficient conditions on the Cauchy data for Einstein equations which insure the existence of Killing fields in a neighborhood of an initial hypersurface has been considered recently by Berezdivin, Coll, and Moncrief. Nevertheless, it can be shown that the evolution equations obtained in all these cases are of nonstrictly hyperbolic type, and, thus, the Cauchy data must belong to a special class of functions. We prove here that, for the vacuum and Einstein--Maxwell space--times and in a coordinate independent way, one can always choose, as evolution equations for the Killing fields, a strictly hyperbolic system: The above theorems can be thus extended to all Cauchy data for which the Einstein evolution problem has been proved to be well set

  12. Food Insecurity: Its Relationship to Dietary Intake and Body Weight among Somali Refugee Women in the United States

    Science.gov (United States)

    Dharod, Jigna M.; Croom, Jamar E.; Sady, Christine G.

    2013-01-01

    Objective: To examine the association between food insecurity, dietary intake, and body mass index among Somali refugee women living in the United States. Methods: Cross-sectional study utilizing the snowball sampling method. Results: Most (67%) participants experienced some level of food insecurity, which was common among recent arrivals and…

  13. The FAV-S Pilot Study: Increasing Self-Efficacy and Fruit and Vegetable Intake Among Somali Women and Children

    Science.gov (United States)

    Kehm, Rebecca; Hearst, Mary O.; Sherman, Shelley; Elwell, Kate L.

    2017-01-01

    The 2012 FAV-S pilot study was developed as a dietary intervention program for low-income Somali mothers grounded in the health belief model. The intervention was geared toward increasing fruit and vegetable intake among participants' children. The purpose of this analysis was to determine the impact of the FAV-S program on participants' (1)…

  14. "And then one day they all moved to Leicester": the relocation of Somalis from the Netherlands to the UK explained.

    NARCIS (Netherlands)

    Liempt, I.C. van

    2011-01-01

    Since 2000 it is estimated that between 10,000 and 20,000 Somali immigrants have left the Netherlands for the UK. This exceptionally high level of intra-European Union (EU) mobility is in contrast with the general trend of very low levels of intra-EU mobility. Based on 33 in-depth interviews

  15. Dervishes, 'moryaan' and freedom fighters : cycles of rebellion and the fragmentation of Somali society, 1900-2000

    NARCIS (Netherlands)

    Abbink, G.J.; Abbink, G.J.; Walraven, van K.; Bruijn, de M.E.

    2003-01-01

    There has been a state of near-permanent revolt in Somali society since 1991. This chapter offers a cultural analysis of patterns of political and military activity from the precolonial era through the Italian and British colonial period, and State independence (1960-1991), to the present period of

  16. Wind power and bird kills

    International Nuclear Information System (INIS)

    Raynolds, M.

    1998-01-01

    The accidental killing of birds by wind generators, and design improvements in the towers that support the turbines that might cut down on the bird killings were discussed. The first problem for the industry began in the late 1980s when the California Energy Commission reported as many as 160 birds (the majority being raptors, including the protected golden eagle) killed in one year in the vicinity of wind power plants. The key factor identified was the design of the towers as birds of prey are attracted to lattice towers as a place to hunt from. Tubular towers do not provide a place for the birds to perch, therefore they reduce the potential for bird strikes. Bird strikes also have been reported in Spain and the siting of the towers have been considered as the principal cause of the bird strikes. In view of these incidents, the wind power industry is developing standards for studying the potential of bird strikes and is continuing to study bird behaviour leading to collisions, the impact of topography, cumulative impacts and new techniques to reduce bird strikes. Despite the reported incidents, the risk of bird strikes by wind turbines, compared to other threats to birds such as pollution, oil spills, and other threats from fossil and nuclear fuels, is considered to be negligible. With continuing efforts to minimize incidents by proper design and siting, wind power can continue to grow as an environmentally sound and efficient source of energy

  17. Wind power and bird kills

    Energy Technology Data Exchange (ETDEWEB)

    Raynolds, M.

    1998-12-01

    The accidental killing of birds by wind generators, and design improvements in the towers that support the turbines that might cut down on the bird killings were discussed. The first problem for the industry began in the late 1980s when the California Energy Commission reported as many as 160 birds (the majority being raptors, including the protected golden eagle) killed in one year in the vicinity of wind power plants. The key factor identified was the design of the towers as birds of prey are attracted to lattice towers as a place to hunt from. Tubular towers do not provide a place for the birds to perch, therefore they reduce the potential for bird strikes. Bird strikes also have been reported in Spain and the siting of the towers have been considered as the principal cause of the bird strikes. In view of these incidents, the wind power industry is developing standards for studying the potential of bird strikes and is continuing to study bird behaviour leading to collisions, the impact of topography, cumulative impacts and new techniques to reduce bird strikes. Despite the reported incidents, the risk of bird strikes by wind turbines, compared to other threats to birds such as pollution, oil spills, and other threats from fossil and nuclear fuels, is considered to be negligible. With continuing efforts to minimize incidents by proper design and siting, wind power can continue to grow as an environmentally sound and efficient source of energy.

  18. Isolated Horizon, Killing Horizon and Event Horizon

    OpenAIRE

    Date, G.

    2001-01-01

    We consider space-times which in addition to admitting an isolated horizon also admit Killing horizons with or without an event horizon. We show that an isolated horizon is a Killing horizon provided either (1) it admits a stationary neighbourhood or (2) it admits a neighbourhood with two independent, commuting Killing vectors. A Killing horizon is always an isolated horizon. For the case when an event horizon is definable, all conceivable relative locations of isolated horizon and event hori...

  19. 33 CFR 117.801 - Newtown Creek, Dutch Kills, English Kills and their tributaries.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Newtown Creek, Dutch Kills, English Kills and their tributaries. 117.801 Section 117.801 Navigation and Navigable Waters COAST GUARD....801 Newtown Creek, Dutch Kills, English Kills and their tributaries. (a) The following requirements...

  20. Killing-Yano tensors and Nambu mechanics

    International Nuclear Information System (INIS)

    Baleanu, D.

    1998-01-01

    Killing-Yano tensors were introduced in 1952 by Kentaro-Yano from mathematical point of view. The physical interpretation of Killing-Yano tensors of rank higher than two was unclear. We found that all Killing-Yano tensors η i 1 i 2 . .. i n with covariant derivative zero are Nambu tensors. We found that in the case of flat space case all Killing-Yano tensors are Nambu tensors. In the case of Taub-NUT and Kerr-Newmann metric Killing-Yano tensors of order two generate Nambu tensors of rank 3

  1. La piratería de derechos de autor y el desarrollo: evidencia de los Estados Unidos en el siglo XIX

    Directory of Open Access Journals (Sweden)

    Zorina Khan

    2008-06-01

    Full Text Available ¿La falta de derechos internacionales de autor beneficia o perjudica a los países en desarrollo? Este artículo examina los efectos de la piratería de derechos de autor en Estados Unidos durante un período cuando era un país en desarrollo. Las leyes estadounidenses protegían los derechos de autor de sus ciudadanos desde 1790, pero hasta 1891 consideraron que las obras de los ciudadanos extranjeros eran de dominio público. En 1891 se modificaron para que los extranjeros obtuvieran protección de derechos de autor si satisfacían ciertas condiciones. Este episodio de la historia estadounidense es útil para investigar las consecuencias de la piratería de derechos internacionales de autor. El análisis usa registros de derechos de autor, información de los autores, títulos y precios de los libros, datos financieros de los balances de una compañía editorial muy importante y demandas judiciales sobre cuestiones de derechos de autor para investigar los efectos de bienestar de la violación de las obras extranjeras sobre los editores, los autores y el público estadounidense. Los resultados indican que Estados Unidos se benefició con la piratería y que la elección del régimen de derechos de autor fue endógena al nivel de desarrollo económico.

  2. A Pirate too Needs to be Heard: Procedural Compromises in Online Copyright Infringement Cases in the UK

    Directory of Open Access Journals (Sweden)

    Poorna Mysoor

    2014-08-01

    Full Text Available Online copyright infringement is one of the toughest challenges the content industry has faced in the twenty first century. Article 8(3 of the Information Society Directive, implemented under section 97A of the UK Copyright, Designs and Patents Act, 1988, provides an injunctive remedy in response to such online infringement. Given the elusive nature of the website operators and the sheer number of their users, rights owners have turned to the Internet Service Providers (ISPs to implement the injunctions granted under section 97A to block websites with infringing content. In their battle to keep pace with online infringers, the UK courts have permitted significant compromises to the procedures while granting these injunctive blocking orders. One of the pioneers in this line of cases in the UK is the Pirate Bay case (TPB case, which ruled as a matter of law that the procedure under Section 97A does not require the alleged infringers to be made parties to those proceedings. TPB case also marks the trend of the ISPs consenting to an order of injunction, and not defending the proceedings. This has resulted in the absence of any adverse party in the proceedings under section 97A. This threatens the basic tenets of procedural fairness and propriety, having adverse consequences on both the substantive and procedural aspects, evident in the cases that followed TPB case. This article examines the aspects of the judgment in TPB case that led to these procedural compromises, whether it had any basis in the pre-existing case law, what the nature of an injunction under section 97A is and how the subsequent line of cases have followed TPB case as a precedent. It further explores the adverse consequences of the procedural compromises and whether any safeguards are available against such compromises.

  3. The Impact of Acculturation Style and Acculturative Hassles on the Mental Health of Somali Adolescent Refugees.

    Science.gov (United States)

    Lincoln, Alisa K; Lazarevic, Vanja; White, Matthew T; Ellis, B Heidi

    2016-08-01

    Refugee adolescents often immigrate to a new society because of experiences of persecution and trauma, which can have profound effects on their mental health. Once they immigrate, many refugees experience stressors related to resettlement and acculturation in the new society. The current study examined relationships among acculturation styles and hassles and the well-being of young refugees as well as the role of gender. Data were collected from 135 young refugees (M age = 15.39, SD = 2.2; 62 % male) from Somalia resettled in the United States The findings from our study indicate that in addition to trauma history, acculturative hassles and acculturation style impact the wellbeing of Somali refugee adolescents. These findings indicate the need to understand both past experiences as well as current challenges. Potential areas for intervention are discussed.

  4. ‘You are labelled by your children’s disability’:A community-based, participatory study of stigma among Somali parents of children with autism living in the United Kingdom

    OpenAIRE

    Selman, Lucy; Fox, Fiona; Aabe, Nura; Turner, Katrina; Rai, Dheeraj; Redwood, Sabi

    2017-01-01

    Objectives: Social stigma is commonly experienced by parents of children with autism. Our aim was to understand the nature of stigma experienced by Somali parents of children with autism in the United Kingdom (UK), and to consider how they coped with or resisted such stigma. Design: We used a community-based participatory research approach, collaborating with a community organisation of Somali parents. In-depth interviews with simultaneous translation were conducted with 15 Somali parents of ...

  5. The ethnic gap in mobility: a comparison of Russian, Somali and Kurdish origin migrants and the general Finnish population

    Directory of Open Access Journals (Sweden)

    S. Rask

    2016-04-01

    Full Text Available Abstract Background Many ethnic minority populations have poorer health than the general population. However, there is limited knowledge on the possible ethnic gap in physical mobility. We aim to examine the prevalence of mobility limitations in working-age Russian, Somali and Kurdish origin migrants in comparison to the general population in Finland. We also determine whether the association between ethnic group and mobility limitation remains after taking into account socio-economic and health-related factors. Methods We used data from the Finnish Migrant Health and Wellbeing Study (Maamu and the Finnish Health 2011 Survey. The participants comprised 1880 persons aged 29–64 years. The age-adjusted prevalence of difficulties in various mobility tasks was calculated using predictive margins. Logistic regression analysis was used to examine the association between socio-economic, health- and migration-related factors and mobility limitation (self-reported difficulty in walking 500 m or stair climbing. The association between ethnic group and mobility limitation was calculated using logistic regression analysis. Results Mobility limitations were much more prevalent among Somali origin women (46 % and Kurdish origin men (32 % and women (57 % compared to men and women in the general Finnish population (5–12 %. In Russian origin men and women, the prevalence of mobility limitation (7–17 % was similar to the general Finnish population. Socio-economic and health-related factors, but not migration-related factors (time lived in Finland and language proficiency in Finnish or Swedish, were found to be associated with mobility limitation in the studied populations. Somali and Kurdish origin migrants were found to have increased odds for mobility limitation compared to the general Finnish population, even after adjusting for socio-economic and health-related factors (Somalis odds ratio [OR] 3.61; 95 % confidence interval [CI] 2.07–6.29, Kurds

  6. Forced residential mobility and social support: impacts on psychiatric disorders among Somali migrants

    Directory of Open Access Journals (Sweden)

    Bhui Kamaldeep

    2012-04-01

    Full Text Available Abstract Background Somali migrants fleeing the civil war in their country face punishing journeys, the loss of homes, possessions, and bereavement. On arrival in the host country they encounter poverty, hostility, and residential instability which may also undermine their mental health. Methods An in-depth and semi-structured interview was used to gather detailed accommodation histories for a five year period from 142 Somali migrants recruited in community venues and primary care. Post-codes were verified and geo-mapped to calculate characteristics of residential location including deprivation indices, the number of moves and the distances between residential moves. We asked about the reasons for changing accommodation, perceived discrimination, asylum status, traumatic experiences, social support, employment and demographic factors. These factors were assessed alongside characteristics of residential mobility as correlates of ICD-10 psychiatric disorders. Results Those who were forced to move homes were more likely to have an ICD-10 psychiatric disorder (OR = 2.64, 1.16-5.98, p = 0.02 compared with those moving through their own choice. A lower risk of psychiatric disorders was found for people with larger friendship networks (0.35, 0.14-0.84, p = 0.02, for those with more confiding emotional support (0.42, 0.18-1.0, p = 0.05, and for those who had not moved during the study period (OR = 0.21, 0.07-0.62, p = 0.01. Conclusions Forced residential mobility is a risk factor for psychiatric disorder; social support may contribute to resilience against psychiatric disorders associated with residential mobility.

  7. Un Análisis de los Impactos de la Estructura de Costos Percibido sobre la Predisposición a la Piratería de Software.

    Directory of Open Access Journals (Sweden)

    Richélita do Rosário Brito Casali

    2014-06-01

    Full Text Available En la literatura académica y profesional, la copia ilegal de software ha sido considerada una de las principales cuestiones éticas de la era de la información. Si, por un lado, las empresas enfrentan dificultades cada vez mayores para lidiar con los problemas derivados del uso ilegal de propiedad intelectual, por otro lado innumerables factores parecen comprometer la percepción de la piratería como crimen. Este artículo procura abordar el asunto a partir de la realidad de los consumidores brasileños, con un análisis de la práctica y de la predisposición de los consumidores de adquirir softwares piratas. Fue realizada una revisión de la literatura y fueron identificados como potenciales factores del comportamiento en cuestión (1 la percepción del daño causado a la firma y (2 el nivel de honestidad personal del consumidor en las relaciones de intercambio. Se realizó un estudio empírico con dos muestras, en el cual quedó demostrado que factores asociados a la percepción de costos prácticamente no ejercen influencia en el comportamiento de los consumidores; se concluye, sin embargo, que la dimensión de honestidad personal tiene efectivamente influencia en el comportamiento de la piratería.

  8. Primera sentencia penal sobre piratería de software analizada a la luz de la informática jurídica

    Directory of Open Access Journals (Sweden)

    Héctor Miguel Delpiano Ascencio

    2015-09-01

    Full Text Available Comentario a la Sentencia del Juzgado Letrado de 1a. Instancia en lo Penal de 6§ Turno, del 23 de marzo de 1993(Con posterioridad a haberse escrito este artículo, el 20 de noviembre de 1997 el Juzgado Letrado de Primera Instancia en lo Penal de 150 Turno (redistribuido del similar de 60 Turno, a cargo del Dr. Gerardo Peduzzi, dictó, en los mismos autos, Sentencia de 1" instancia condenatoria por un "delito continuado de reproducción ilícita de una obra literaria", la que, en momentos de incorporarse esta nota (abril de 1998, está sienpo objeto de recurso de apelación por el condenado. La Sentencia de 1" instancia será analizada oportunamente una vez resuelto el recurso y en conjunto con la de 2a instancia, si introdujeran elementos innovadores respecto a los contenidos en el presente trabajo.Contenido: Generalidades. Alcance del término "software". Concepto de licencia. Circunstancias de hecho determinantes de la sentencia. Delito tipificado: "piratería de software". Circunstancias que llevaron a la tipificación. Modalidades de pirateríacometidas. Elementos de la comisión del delito. Otros conceptos manejados en lasentencia.  Software de Base. La factura no significa tener licencia. Normativa aplicada al caso. Normativa nacional. Normativa internacional. 

  9. Somali Syntax,

    Science.gov (United States)

    1979-01-01

    they - go The Vietnamese people should be allowed the right of determining their own destiny . 174" a.- ] !- ’--- _ (373) Anaa warrameya. I/SP (baa... embryo of a form of prepositional government which is the same for verbs and nouns alike and which is developing on the basis of a spatial noun

  10. The cultural basis for oral health practices among Somali refugees pre-and post-resettlement in Massachusetts.

    Science.gov (United States)

    Adams, Jo Hunter; Young, Samorga; Laird, Lance D; Geltman, Paul L; Cochran, Jennifer J; Hassan, Ahmed; Egal, Fadumo; Paasche-Orlow, Michael K; Barnes, Linda L

    2013-11-01

    Oral health disparities related to socioeconomic status have been well described in the U.S., but oral health among refugee groups has not been well characterized. This article examines oral health among Somali refugees in Massachusetts. Eighty-three (83) participants were purposively selected for an in-depth, open-ended interview related to oral health. Older individuals associated use of the stick brush with the Islamic practice of cleansing before prayer. When unable to find stick brushes in the U.S., many adopted the Western toothbrush. Parents expressed concern that their children had adopted U.S. practices of brushing with a toothbrush only once or twice a day. Somali oral health practices have changed following arrival to the U.S., but the underlying model for oral health care remains rooted in Islam. By acknowledging the value of traditional practices, dentists may communicate the value of Western preventive and restorative dentistry, and recommend approaches to integrating the two.

  11. Timelike Killing spinors in seven dimensions

    International Nuclear Information System (INIS)

    Cariglia, Marco; Conamhna, Oisin A.P. Mac

    2004-01-01

    We employ the G-structure formalism to study supersymmetric solutions of minimal and SU(2) gauged supergravities in seven dimensions admitting Killing spinors with an associated timelike Killing vector. The most general such Killing spinor defines a SU(3) structure. We deduce necessary and sufficient conditions for the existence of a timelike Killing spinor on the bosonic fields of the theories, and find that such configurations generically preserve one out of 16 supersymmetries. Using our general supersymmetric ansatz we obtain numerous new solutions, including squashed or deformed anti-de Sitter solutions of the gauged theory, and a large class of Goedel-like solutions with closed timelike curves

  12. Evaluation of Honour Killings in Turkey

    OpenAIRE

    Celbis, Osman; Ozdemir, Bora; Oruc, Mucahit; Dogan, Mustafa; Egri, Mucahit

    2013-01-01

    Honour killings are still pervasive in many societies.  The aim of this study is to reveal the characteristics of the victims of honour killings and honour killers in Malatya province between 2000 and 2004, and to review the concept of honour killings in Turkey.  Data are collected from the records of Malatya Higher Criminal Court.  The results are discussed in the light of the data obtained from Turkish Republic Ministry of Justice.  There were 36 honour killings in Malatya between 2000 and ...

  13. Bibliografía sobre comercio marítimo, contrabando y piratería en las Antillas y el Caribe (artículos, ponencias y tesis desde 1980

    Directory of Open Access Journals (Sweden)

    Rodríguez Yunta, Luis

    1994-12-01

    Full Text Available Not available.

    Recopilación bibliográfica sobre comercio marítimo, contrabando y piratería en las Antillas y el Caribe, realizada sobre la base de la información disponible en las bases de datos América Latina (CSIC e Historical Abstract.

  14. Bibliografía sobre comercio marítimo, contrabando y piratería en las Antillas y el Caribe (artículos, ponencias y tesis desde 1980)

    OpenAIRE

    Rodríguez Yunta, Luis

    1994-01-01

    Not available.

    Recopilación bibliográfica sobre comercio marítimo, contrabando y piratería en las Antillas y el Caribe, realizada sobre la base de la información disponible en las bases de datos América Latina (CSIC) e Historical Abstract.

  15. Effects of polio eradication activities on routine immunization: lessons from the 2013 outbreak response in Somali region of Ethiopia

    OpenAIRE

    Tafesse, Belete; Tekle, Ephrem; Wondwossen, Liya; Bogale, Mengistu; Fiona, Braka; Nsubuga, Peter; Tomas, Karengera; Kassahun, Aron; Kathleen, Gallagher; Teka, Aschalew

    2017-01-01

    Introduction Ethiopia experienced several WPV importations with a total of 10 WPV1 cases confirmed during the 2013 outbreak alone before it is closed in 2015. We evaluated supplemental immunization activities (SIAs), including lessons learned for their effect on the routine immunization program during the 2013 polio outbreak in Somali regional state. Methods We used descriptive study to review documents and analyse routine health information system reports from the polio outbreak affected Som...

  16. Food and Nutrient Intake among 12-Month-Old Norwegian-Somali and Norwegian-Iraqi Infants.

    Science.gov (United States)

    Grewal, Navnit Kaur; Andersen, Lene Frost; Kolve, Cathrine Solheim; Kverndalen, Ingrid; Torheim, Liv Elin

    2016-09-28

    The aim of the present paper was to describe food and nutrient intake among 12-month-old Norwegian-Somali and Norwegian-Iraqi infants, with a focus on iron and vitamin D intake. A cross-sectional survey was conducted from August 2013 through September 2014. Eighty-nine mothers/infants of Somali origin and 77 mothers/infants of Iraqi origin residing in Eastern Norway participated in the study. Data were collected using two 24-h multiple-pass recalls. Forty percent of the Norwegian-Somali infants and 47% of the Norwegian-Iraqi infants were breastfed at 12 months of age ( p = 0.414). Median energy percentages (E%) from protein, fat and carbohydrates were within the recommended intake ranges, except the level of saturated fats (12-13 E%). Median intakes of almost all micronutrients were above the recommended daily intakes. Most of the infants consumed iron-enriched products (81%) and received vitamin D supplements (84%). The median intakes of iron and vitamin D were significantly higher among infants receiving iron-enriched products and vitamin D supplements compared to infants not receiving such products ( p food and nutrient intake of this group of infants in general seems to be in accordance with Norwegian dietary recommendations. Foods rich in iron and vitamin D supplements were important sources of the infants' intake of iron and vitamin D and should continue to be promoted.

  17. On integrability of the Killing equation

    Science.gov (United States)

    Houri, Tsuyoshi; Tomoda, Kentaro; Yasui, Yukinori

    2018-04-01

    Killing tensor fields have been thought of as describing the hidden symmetry of space(-time) since they are in one-to-one correspondence with polynomial first integrals of geodesic equations. Since many problems in classical mechanics can be formulated as geodesic problems in curved space and spacetime, solving the defining equation for Killing tensor fields (the Killing equation) is a powerful way to integrate equations of motion. Thus it has been desirable to formulate the integrability conditions of the Killing equation, which serve to determine the number of linearly independent solutions and also to restrict the possible forms of solutions tightly. In this paper, we show the prolongation for the Killing equation in a manner that uses Young symmetrizers. Using the prolonged equations, we provide the integrability conditions explicitly.

  18. Antibacterial surface design - Contact kill

    Science.gov (United States)

    Kaur, Rajbir; Liu, Song

    2016-08-01

    Designing antibacterial surfaces has become extremely important to minimize Healthcare Associated Infections which are a major cause of mortality worldwide. A previous biocide-releasing approach is based on leaching of encapsulated biocides such as silver and triclosan which exerts negative impacts on the environment and potentially contributes to the development of bacterial resistance. This drawback of leachable compounds led to the shift of interest towards a more sustainable and environmentally friendly approach: contact-killing surfaces. Biocides that can be bound onto surfaces to give the substrates contact-active antibacterial activity include quaternary ammonium compounds (QACs), quaternary phosphoniums (QPs), carbon nanotubes, antibacterial peptides, and N-chloramines. Among the above, QACs and N-chloramines are the most researched contact-active biocides. We review the engineering of contact-active surfaces using QACs or N-chloramines, the modes of actions as well as the test methods. The charge-density threshold of cationic surfaces for desired antibacterial efficacy and attempts to combine various biocides for the generation of new contact-active surfaces are discussed in detail. Surface positive charge density is identified as a key parameter to define antibacterial efficacy. We expect that this research field will continue to attract more research interest in view of the potential impact of self-disinfective surfaces on healthcare-associated infections, food safety and corrosion/fouling resistance required on industrial surfaces such as oil pipes and ship hulls.

  19. Germ killing by ultraviolet radiation

    International Nuclear Information System (INIS)

    Wawrik, O.

    1975-01-01

    Short-wave UV radiation, in particular the range about 250 nm, has a high germ reducing effect. Corresponding UV burners which above all emit radiation at the line of 254 nm can therefore be used effectively in all cases where the least possible content of germs in the air is aimed at. Apart from this it is also possible to reduce by this process the germs on surfaces and liquids. Especially in the most various ranges of pharmaceutical production one is steadily striving for efficient and last not least economic procedures by which it is possible to reduce the germs present in the air of a room. Numerous scientific investigations have sufficiently proved that short-wave UV radiation is extremely well appropriate for such purposes. Absolutely germ-free air in a room can only be obtained under laboratory conditions. In practice, however, the aim is not to achieve a 100 per cent killing of the germs present in a room but to make sure that the germ rate in certain rooms is constantly reduced to the lowest possible level. If in this connection it is referred to a germ reduction of 100 or 99 per cent this is but theory. (orig.) [de

  20. More than re-establishing the partner relationship: Intimate aftercare for Somali parents in diaspora.

    Science.gov (United States)

    Binder, Pauline; Johnsdotter, Sara; Essén, Birgitta

    2013-08-01

    to explore the sexual relationship and couples' perceptions about intimate partner support following childbirth. a hermeneutic design using a naturalistic inquiry framework as a qualitative proxy for medical anthropology. Data were collected using a fictional and culturally-specific narrative during focus group discussions (FGDs) in early 2011. Analysis was conducted by 'functional narrative analysis' and interpreted for conceptual constructions. Recruitment was by snowball and purposive sampling. a diasporic context among participants living in six urban centres across Sweden. successful recruitment included 16 Somali-Swedish fathers and 27 mothers. Three FDGs were conducted with fathers (3-7 participants) and seven with mothers (3-6 participants). within day 40 post partum, parents learn to rely on each other in the absence of traditional support networks. After the first 40 days, the re-introduction of sexual intimacy is likely to occur. Of the fathers experiencing postpartum sexual aversion, these seemed to experience 'existential angst' resulting from a combination of profound remorse over having put the partner into what they perceived as a life-threatening situation during childbirth and their perceived moral and ethical obligations to provide support in this setting. Mothers in general did not directly discuss their own sexuality. Women could imagine men's sexual aversion after witnessing childbirth. However, they seemed unaware of men's potential for angst. Mothers are situated between the loss of traditional postpartum support networks, comprised of close female kin, and their own newly-defined responsibilities in the host setting. Fathers embrace their new role. Both partners articulated the mother's new role as enhancing autonomy and independence in the host setting. However, women held mixed attitudes about fathers replacing traditional kin support. to date, late postpartum aftercare for immigrant African parents is anecdotally linked to evidence

  1. Communication and cultural issues in providing reproductive health care to immigrant women: health care providers' experiences in meeting the needs of [corrected] Somali women living in Finland.

    Science.gov (United States)

    Degni, Filio; Suominen, Sakari; Essén, Birgitta; El Ansari, Walid; Vehviläinen-Julkunen, Katri

    2012-04-01

    Communication problems due to language and cultural differences between health care professionals and patients are widely recognized. Finns are described as more silent whereas one concurrent large immigrant group, the Somalis, are described as more open in their communication. The aim of the study was to explore physicians-nurses/midwives' communication when providing reproductive and maternity health care to Somali women in Finland. Four individual and three focus group interviews were carried out with 10 gynecologists/obstetricians and 15 nurses/midwives from five selected clinics. The health care providers considered communication (including linguistic difficulties), cultural traditions, and religious beliefs to be problems when working with Somali women. Male and female physicians were generally more similar in communication style, interpersonal contacts, and cultural awareness than the nurses/midwives who were engaged in more partnership-building with the Somali women in the clinics. Despite the communication and cultural problems, there was a tentative mutual understanding between the Finnish reproductive health care professionals and the Somali women in the clinics.

  2. High frequencies of Y chromosome lineages characterized by E3b1, DYS19-11, DYS392-12 in Somali males

    DEFF Research Database (Denmark)

    Sanchez Sanchez, Juan Jose; Hallenberg, Charlotte; Børsting, Claus

    2005-01-01

    We genotyped 45 biallelic markers and 11 STR systems on the Y chromosome in 201 male Somalis. In addition, 65 sub-Saharan Western Africans, 59 Turks and 64 Iraqis were typed for the biallelic Y chromosome markers. In Somalis, 14 Y chromosome haplogroups were identified including E3b1 (77.6%) and K2...... (10.4%). The haplogroup E3b1 with the rare DYS19-11 allele (also called the E3b1 cluster gamma) was found in 75.1% of male Somalis, and 70.6% of Somali Y chromosomes were E3b1, DYS19-11, DYS392-12, DYS437-14, DYS438-11 and DYS393-13. The haplotype diversity of eight Y-STRs ('minimal haplotype') was 0......f2) (27.1%), R1b3*(xR1b3d, R1b3f) (20.3%), E3b3 and R1a1*(xR1a1b) (both 11.9%). In Iraqis, 12 haplogroups were identified including J2*(xJ2f2) (29.7%) and J*(xJ2) (26.6%). The data suggest that the male Somali population is a branch of the East African population - closely related to the Oromos...

  3. Diabetes Risk by Length of Residence among Somali Women in Oslo Area.

    Science.gov (United States)

    Gele, Abdi A; Pettersen, Kjell Sverre; Kumar, Bernadette; Torheim, Liv Elin

    2016-01-01

    Type 2 diabetes represents a major health problem worldwide, with immigrants strongly contributing to the increase in diabetes in many countries. Norway is not immune to the process, and immigrants in the country are experiencing an increase in the prevalence of diabetes after arrival. However, the dynamics of these transitions in relation to the duration of residence in the new environment in Norway are not clearly understood. From this background, a cross-sectional quantitative study using a respondent-driven sampling method was conducted among 302 Somali women living in Oslo area. The results show that 41% of the study participants will be at risk for developing diabetes in the coming 10 years, which coincides with 85% of the study participants being abdominally obese. Significant associations were found between years of stay in Norway and the risk for diabetes with those who lived in Norway >10 years, having twofold higher odds of being at risk for developing diabetes compared to those who lived in Norway ≤5 years (OR: 2.16, CI: 1.08-4.32). Understanding the mechanisms through which exposure to the Norwegian environment leads to higher obesity and diabetes risk may aid in prevention efforts for the rapidly growing African immigrant population.

  4. Neoliberal Sexual Humanitarianism and Story-Telling: The case of Somaly Mam

    Directory of Open Access Journals (Sweden)

    Heidi Hoefinger

    2016-09-01

    Full Text Available Stories of trafficking into the sex industry in Cambodia are a popular feature in local and international media, academic and development literature, policy and humanitarian debates, social and political discourse, and NGO interventions. These stories are powerful for their ability to evoke deep emotions and outrage from their intended audiences. However, they are equally powerful for the ways in which they can cause harm—namely to already marginalised populations of migrants and people involved in the sex trade either by choice, circumstance or coercion. One of the most contentious contemporary trafficking stories is that of the controversial case of Somaly Mam—the self-declared ‘sex slave’ turned ‘modern-day hero’. This paper outlines Mam’s prolific trajectory of self-representation according to the tropes of sexual humanitarianism and argues that these narratives helped to set in motion one of the most lucrative, and in many ways, most exploitative and problematic anti-trafficking endeavours in Cambodia, to date. The paper concludes with offering suggestions for how the anti-trafficking industry might better address real cases of trafficking and exploitation by focusing on structural violence and systemic injustice rather than on sensationalised humanitarian rhetoric, which can perpetuate harms.

  5. Diabetes Risk by Length of Residence among Somali Women in Oslo Area

    Directory of Open Access Journals (Sweden)

    Abdi A. Gele

    2016-01-01

    Full Text Available Type 2 diabetes represents a major health problem worldwide, with immigrants strongly contributing to the increase in diabetes in many countries. Norway is not immune to the process, and immigrants in the country are experiencing an increase in the prevalence of diabetes after arrival. However, the dynamics of these transitions in relation to the duration of residence in the new environment in Norway are not clearly understood. From this background, a cross-sectional quantitative study using a respondent-driven sampling method was conducted among 302 Somali women living in Oslo area. The results show that 41% of the study participants will be at risk for developing diabetes in the coming 10 years, which coincides with 85% of the study participants being abdominally obese. Significant associations were found between years of stay in Norway and the risk for diabetes with those who lived in Norway >10 years, having twofold higher odds of being at risk for developing diabetes compared to those who lived in Norway ≤5 years (OR: 2.16, CI: 1.08–4.32. Understanding the mechanisms through which exposure to the Norwegian environment leads to higher obesity and diabetes risk may aid in prevention efforts for the rapidly growing African immigrant population.

  6. Affiliative and aggressive behavior in a group of female Somali wild ass (Equus africanus somalicus).

    Science.gov (United States)

    Asa, Cheryl S; Marshall, Fiona; Fischer, Martha

    2012-01-01

    We observed a group of three young female Somali wild asses to develop an ethogram of social behavior in the first phase of a longer term study of social, sexual, and maternal/infant behavior. The most unexpected finding was the frequency and extent of aggressive interactions, which included Charge, Drive, Neck Wrestle, Head Butt, and Body Slam, behaviors previously reported only for males of other equid species. The overall frequency of aggressive behavior was higher than that of affiliative behavior (84±16.5 vs. 32±5.5, P=0.03), yet no injuries occurred. The dyadic directionality of aggressive behavior suggested a dominance hierarchy, a feature not previously reported for either wild ass or domestic donkeys. The aggression observed may be an accurate representation of the behavior of this species, or their relatively young ages, or their recent transfer from their natal group through quarantine and into a new enclosure may have heightened agonistic tendencies. Further studies will determine whether with time their aggressive behavior becomes more intense or dissipates with maturity. © 2011 Wiley Periodicals, Inc.

  7. Prevalence and Distribution of Schistosomiasis in Afder and Gode Zone of Somali Region, Ethiopia

    Science.gov (United States)

    Negussu, Nebiyu; Wali, Mohamed; Ejigu, Milion; Debebe, Fikiru; Aden, Sirage; Abdi, Rashid; Mohamed, Yusuf; Deribew, Amare; Deribe, Kebede

    2013-01-01

    Background: There is no recent information about the prevalence and distribution of schistosomiasis in the Somali national regional state of Ethiopia. Ethiopia launched the national integrated neglected tropical diseases (NTDs) Master Plan in June 2013. The Master Plan identified mapping NTDs as a prerequisite for launching control programs. Therefore it is important to understand the prevalence and distribution of schistosomiasis in respective regions. Materials and Methods: From February to March 2011, a cross-sectional survey was done in school-aged children from six districts of Afder Gode zone. Urine samples were collected and examined for ova of Schistosoma haematobium using the sedimentation technique and stool samples were collected and examined for S. mansoni using the Kato-Katz technique. A semistructured questionnaire was used to collect sociodemographic characteristics of the participants. Results: Of the 523 children, 513 (98%) of them participated in the study. The prevalence of S. haematobium was 16.0% (95% confidence interval (CI); 12.8-19.2). The rate of the disease was not uniform across the various six communities studied (x2 = 208.8, P region with varying distribution across the districts. According to the World Health Organization, mass drug administration should be considered in some of the districts. PMID:24672176

  8. Juvenile hyposomatotropism in a Somali cat presenting with seizures due to intermittent hypoglycaemia

    Directory of Open Access Journals (Sweden)

    Maya Laura König

    2018-03-01

    Full Text Available Case summary A 3-month-old intact male Somali cat was evaluated for a history of seizures, hypoglycaemia and mental dullness 4 weeks after being bitten in the head by a dog. The cat’s body size and weight were approximately half that of his littermates and its haircoat was woolly, with fewer guard hairs. Multiple hypoglycaemic episodes were documented over a period of 4 weeks, which resolved rapidly after correction of the hypoglycaemia. Juvenile hyposomatotropism was presumptively diagnosed by demonstrating low circulating levels of insulin-like growth factor 1 and after exclusion of other endocrine and non-endocrine causes of small stature and hypoglycaemia. The cat’s intermittent hypoglycaemia resolved spontaneously within 1 month and the cat never showed any more neurological signs. Nevertheless, the physical retardation and the coat abnormalities remained unchanged. A year later, the cat was diagnosed with chronic kidney disease IRIS stage 2. Relevance and novel information Hyposomatotropism is an extremely rare feline endocrinopathy. This is the second case reported in the veterinary literature, and the only one to describe hypoglycaemic events associated with growth hormone deficiency. Although hypoglycaemia is one of the most common disease manifestations in children with pituitary dwarfism, this has not yet been reported in veterinary medicine.

  9. Honor Killing: Where Pride Defeats Reason.

    Science.gov (United States)

    Kanchan, Tanuj; Tandon, Abhishek; Krishan, Kewal

    2016-12-01

    Honor killings are graceless and ferocious murders by chauvinists with an antediluvian mind. These are categorized separately because these killings are committed for the prime reason of satisfying the ego of the people whom the victim trusts and always looks up to for support and protection. It is for this sole reason that honor killings demand strict and stern punishment, not only for the person who committed the murder but also for any person who contributed or was party to the act. A positive change can occur with stricter legislation and changes in the ethos of the society we live in today.

  10. Some basic properties of Killing spinors

    International Nuclear Information System (INIS)

    Hacyan, S.; Plebanski, J.

    1976-01-01

    The concept of Killing spinor is analyzed in a general way by using the spinorial formalism. It is shown, among other things, that higher derivatives of Killing spinors can be expressed in terms of lower order derivatives. Conformal Killing vectors are studied in some detail in the light of spinorial analysis: Classical results are formulated in terms of spinors. A theorem on Lie derivatives of Debever--Penrose vectors is proved, and it is shown that conformal motion in vacuum with zero cosmological constant must be homothetic, unless the conformal tensor vanishes or is of type N. Our results are valid for either real or complex space--time manifolds

  11. Poachers and pirates

    African Journals Online (AJOL)

    60 • JuNe 2017. * Olga Biegus is an MPhil Researcher at the University of Cape ... at Cardiff University. Poachers ..... come into effect as 2017 starts, Press Release, 2 January. 2017 ... police or park rangers are often actively involved in wildlife.

  12. Homefucking is Killing Prostitution / Taavi Eelmaa

    Index Scriptorium Estoniae

    Eelmaa, Taavi, 1971-

    2008-01-01

    Mis jääb vaatajale teatrietendusest meelde? Ilmus Kris Moori raamat "Homefucking is Killing Prostitution". Raamat sisaldab tekste ja Erki Lauri fotosid Von Krahli Teatri samanimelisest etendusest, mida kordagi ei mängitud

  13. KILLING, VIEWED FROM A CONFLICT RESOLUTION PERSPECTIVE

    African Journals Online (AJOL)

    DODO

    2017-07-01

    Jul 1, 2017 ... ... million people were killed as part of the industrial policy of Belgium's ..... the seeds of hate and further conspiracies against others, the entire .... International Commission On Intervention and State Sovereignty (ICISS) 2001.

  14. Cryptococcus neoformans modulates extracellular killing by neutrophils

    Directory of Open Access Journals (Sweden)

    Asfia eQureshi

    2011-09-01

    Full Text Available We recently established a key role for host sphingomyelin synthase (SMS in the regulation of the killing activity of neutrophils against Cryptococcus neoformans. In this work, we studied the effect of C. neoformans on the killing activity of neutrophils and whether SMS would still be a player against C. neoformans in immunocompromised mice lacking T and NK cells (Tgε26 mice. To this end, we analyzed whether C. neoformans would have any effect on neutrophil survival and killing in vitro and in vivo. We show that unlike C. albicans, neither the presence nor the capsule size of C. neoformans cells have any effect on neutrophil viability. Interestingly, melanized C. neoformans cells totally abrogated the killing activity of neutrophils. Next, we monitored how exposure of neutrophils to C. neoformans cells would interfere with any further killing activity of the medium and found that pre-incubation with live but not heat-killed fungal cells significantly inhibits further killing activity of the medium. We next studied whether activation of SMS at the site of C. neoformans infection is dependent on T and NK cells. Using matrix-assisted laser desorption-ionization (MALDI tissue imaging in infected lung we found that similarly to previous observations in the isogenic wild type CBA/J mice, SM 16:0 levels are significantly elevated at the site of infection in mice lacking T and NK cells but only at early time points. This study highlights that C. neoformans may negatively regulate the killing activity of neutrophils and that SMS activation in neutrophils appears to be partially independent of T and/or NK cells.

  15. Targeted Killings in Bangladesh: Diversity at Stake

    OpenAIRE

    Syed, Jawad

    2016-01-01

    Since 2013, Bangladesh has repeatedly been in headline news across the world due to systematic and incessant targeted killings. In the mainstream media, both in South Asia and the West, the focus has been generally on high profile murders of secular and progressive bloggers. This includes the recent worldwide broad coverage on the tragic murder of Xulhaz Mannan, editor of Bangladesh's first LGBT rights magazine. However, not many know that these killings are only one part of the story. Secula...

  16. Contagion in Mass Killings and School Shootings

    OpenAIRE

    Towers, Sherry; Gomez-Lievano, Andres; Khan, Maryam; Mubayi, Anuj; Castillo-Chavez, Carlos

    2015-01-01

    Background Several past studies have found that media reports of suicides and homicides appear to subsequently increase the incidence of similar events in the community, apparently due to the coverage planting the seeds of ideation in at-risk individuals to commit similar acts. Methods Here we explore whether or not contagion is evident in more high-profile incidents, such as school shootings and mass killings (incidents with four or more people killed). We fit a contagion model to recent dat...

  17. Dirac operators and Killing spinors with torsion

    International Nuclear Information System (INIS)

    Becker-Bender, Julia

    2012-01-01

    On a Riemannian spin manifold with parallel skew torsion, we use the twistor operator to obtain an eigenvalue estimate for the Dirac operator with torsion. We consider the equality case in dimensions four and six. In odd dimensions we describe Sasaki manifolds on which equality in the estimate is realized by Killing spinors with torsion. In dimension five we characterize all Killing spinors with torsion and obtain certain naturally reductive spaces as exceptional cases.

  18. Technical Aspects of Cyber Kill Chain

    OpenAIRE

    Yadav, Tarun; Mallari, Rao Arvind

    2016-01-01

    Recent trends in targeted cyber-attacks has increased the interest of research in the field of cyber security. Such attacks have massive disruptive effects on rganizations, enterprises and governments. Cyber kill chain is a model to describe cyber-attacks so as to develop incident response and analysis capabilities. Cyber kill chain in simple terms is an attack chain, the path that an intruder takes to penetrate information systems over time to execute an attack on the target. This paper broa...

  19. Killing-Yano tensors, rank-2 Killing tensors, and conserved quantities in higher dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Krtous, Pavel [Institute of Theoretical Physics, Charles University, V Holesovickach 2, Prague (Czech Republic); Kubiznak, David [Institute of Theoretical Physics, Charles University, V Holesovickach 2, Prague (Czech Republic); Page, Don N. [Theoretical Physics Institute, University of Alberta, Edmonton T6G 2G7, Alberta (Canada); Frolov, Valeri P. [Theoretical Physics Institute, University of Alberta, Edmonton T6G 2G7, Alberta (Canada)

    2007-02-15

    From the metric and one Killing-Yano tensor of rank D-2 in any D-dimensional spacetime with such a principal Killing-Yano tensor, we show how to generate k = [(D+1)/2] Killing-Yano tensors, of rank D-2j for all 0 {<=} j {<=} k-1, and k rank-2 Killing tensors, giving k constants of geodesic motion that are in involution. For the example of the Kerr-NUT-AdS spacetime (hep-th/0604125) with its principal Killing-Yano tensor (gr-qc/0610144), these constants and the constants from the k Killing vectors give D independent constants in involution, making the geodesic motion completely integrable (hep-th/0611083). The constants of motion are also related to the constants recently obtained in the separation of the Hamilton-Jacobi and Klein-Gordon equations (hep-th/0611245)

  20. Killing-Yano tensors, rank-2 Killing tensors, and conserved quantities in higher dimensions

    International Nuclear Information System (INIS)

    Krtous, Pavel; Kubiznak, David; Page, Don N.; Frolov, Valeri P.

    2007-01-01

    From the metric and one Killing-Yano tensor of rank D-2 in any D-dimensional spacetime with such a principal Killing-Yano tensor, we show how to generate k = [(D+1)/2] Killing-Yano tensors, of rank D-2j for all 0 ≤ j ≤ k-1, and k rank-2 Killing tensors, giving k constants of geodesic motion that are in involution. For the example of the Kerr-NUT-AdS spacetime (hep-th/0604125) with its principal Killing-Yano tensor (gr-qc/0610144), these constants and the constants from the k Killing vectors give D independent constants in involution, making the geodesic motion completely integrable (hep-th/0611083). The constants of motion are also related to the constants recently obtained in the separation of the Hamilton-Jacobi and Klein-Gordon equations (hep-th/0611245)

  1. Lay explanatory models of depression and preferred coping strategies among Somali refugees in Norway. A mixed method study

    Directory of Open Access Journals (Sweden)

    Valeria Markova

    2016-09-01

    Full Text Available Objective. Refugees are at high risk for mental health problems due to trauma in their pasts and to acculturation stress as they settle in a new country. To develop efficient health services to meet the needs of refugees from various regions, an understanding of how they make sense of and prefer to cope with mental health problems is warranted. This study aims to investigate lay explanatory models of depression and preferred coping strategies among Somali refugees in Norway.Methods. The study used a mixed-method design with a vignette describing a moderately depressed person based on ICD-10 criteria. Firstly, a survey study was performed among Somali refugees (n = 101. Respondents were asked to provide advice to the vignette character, completing the Cross-Cultural Depression Coping Inventory and the General Help-Seeking Questionnaire. Secondly, focus group interviews (n = 10 were done separately with males and females to examine the relationship between the explanatory models of depression and preferred coping strategies.Results. The participants showed a strong preference for coping with depression by religious practices and reliance on family, friends, and their ethnic/religious community rather than seeking professional treatment from public health services (e.g., medical doctors, psychologists. Depressive symptoms were conceptualized as a problem related to cognition (thinking too much and emotion (sadness, but not with biological mechanisms, and were thought to result from spiritual possessions, stress from social isolation, and/or past trauma. Independent of time in exile, the participants showed a strong identification with their ethnic origin and associated values. As participants emphasized the need to obey and follow the viewpoint of elders, fathers, and spiritual leaders, these authorities seemed to be gatekeepers for access to mental health services. Conclusion. The results highlight that mental health programs for Somali refugees

  2. Barriers and facilitators to cervical cancer screening among Pakistani and Somali immigrant women in Oslo: a qualitative study.

    Science.gov (United States)

    Gele, Abdi A; Qureshi, Samera A; Kour, Prabhjot; Kumar, Bernadette; Diaz, Esperanza

    2017-01-01

    Norway has a low incidence and mortality rate of cervical cancer, which is mainly due to the high participation rate of women in cervical cancer screening. However, the attendance of cervical cancer screening was reported to be low among immigrant women. For this reason, we conducted a qualitative study to obtain better insight into perceived barriers and challenges to cervical cancer screening among Somali and Pakistani women in the Oslo region. A convenient sample of 35 (18 Pakistani, 17 Somali) women were recruited for the study in collaboration with Somali and Pakistani community partners. Focus group discussions were used to explore barriers and facilitators to cervical cancer screening, whereas the Ecological Model was used as the framework for the study. The study found three levels of barriers to cervical cancer screening. The individual level included a lack of understanding of the benefits of the screening. The sociocultural level included the stigma attached to the disease and the belief that women who are unmarried are sexually inactive. The system-related level included a lack of trust toward the health care system. Based on the study results, and using a common denominator approach for the immigrant groups included, the study recommends three communication strategies with the potential to improve women's participation in cervical cancer screening: 1) in-person communication and information material at health centers; 2) verbal communication with women through seminars and workshops to educate them about their risk of cancer and the importance of screening and 3) the initiation of better recall through SMS and letters written in native languages. Finally, an intervention study that compares the aforementioned strategies and proves their effectiveness in increasing immigrant women's participation in cervical cancer screening is recommended.

  3. PESAN MORAL DALAM FILM TO KILL A MOCKINGBIRD (ANALISIS SEMIOTIKA PADA FILM TO KILL A MOCKINGBIRD

    OpenAIRE

    RENYOET, JAQUILINE MELISSA

    2014-01-01

    2014 JAQUILINE MELISSA RENYOET. Pesan Moral Dalam Film To Kill A Mockingbird (Analisis Semiotika Pada Film To Kill A Mockingbird). (Dibimbing oleh Muh. Nadjib dan Alem Febri Sonni). Tujuan Penelitian ini adalah mengidentifikasi bentuk pesan moral dan memahami makna pesan moral dalam film To Kill A Mockingbird. Penelitian ini dilakukan selama kurang lebih 2 bulan yaitu Maret ??? Mei 2014. Metode yang digunakan untuk penelitian ini adalah metode penelitian kualitatif den...

  4. Barriers and facilitators to cervical cancer screening among Pakistani and Somali immigrant women in Oslo: a qualitative study

    Directory of Open Access Journals (Sweden)

    Gele AA

    2017-07-01

    Full Text Available Abdi A Gele,1,2 Samera A Qureshi,1 Prabhjot Kour,1 Bernadette Kumar,1 Esperanza Diaz1,3 1Norwegian Center for Minority Health Research, 2Department of Health, Institute of Nursing and Health Promotion, Oslo and Akershus University College, Oslo; 3Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway Abstract: Norway has a low incidence and mortality rate of cervical cancer, which is mainly due to the high participation rate of women in cervical cancer screening. However, the attendance of cervical cancer screening was reported to be low among immigrant women. For this reason, we conducted a qualitative study to obtain better insight into perceived barriers and challenges to cervical cancer screening among Somali and Pakistani women in the Oslo region. A convenient sample of 35 (18 Pakistani, 17 Somali women were recruited for the study in collaboration with Somali and Pakistani community partners. Focus group discussions were used to explore barriers and facilitators to cervical cancer screening, whereas the Ecological Model was used as the framework for the study. The study found three levels of barriers to cervical cancer screening. The individual level included a lack of understanding of the benefits of the screening. The sociocultural level included the stigma attached to the disease and the belief that women who are unmarried are sexually inactive. The system-related level included a lack of trust toward the health care system. Based on the study results, and using a common denominator approach for the immigrant groups included, the study recommends three communication strategies with the potential to improve women’s participation in cervical cancer screening: 1 in-person communication and information material at health centers; 2 verbal communication with women through seminars and workshops to educate them about their risk of cancer and the importance of screening and 3 the initiation of better recall

  5. Childhood lead poisoning in a Somali refugee resettlement community in New Hampshire.

    Science.gov (United States)

    Caron, Rosemary M; Tshabangu-Soko, Thandi; Finefrock, Krysten

    2013-08-01

    Despite the gradual decrease in childhood lead poisoning in the United States, the risk for lead poisoning among African refugee children who resettle in the United States remains elevated. Communication methods implemented by resettlement agencies in the public health system for preventing childhood lead poisoning in this at-risk population warrant further investigation. We utilized structured interviews with key stakeholders (resettlement agencies, social service agencies developed by African refugees and resettled Somali refugees) involved in the refugee resettlement process to (1) describe the agency's role in the refugee resettlement process; (2) examine communication methods utilized and barriers experienced by the public health system in reference to childhood lead poisoning; (3) describe the refugee population's perception of childhood lead poisoning; (4) examine general challenges experienced by the public health system and the refugee population during the resettlement process; and (5) describe stakeholders' recommendations to improve health communication efforts. Based on our findings, we propose that communities are important determinants in health-related problems for refugee populations. Each community has its own environment and public health system that interacts with each other to influence health risks and risk perceptions of its populations. We advocate that understanding a community's ecology and implementing a culture-centered approach is essential for the public health system to help educate and prevent communication inequalities and health disparities among an at-risk African refugee population. This action can reduce a population's resistance to communication and help build a community's capacity to address a persistent public health problem, such as childhood lead poisoning.

  6. Chemically enhanced sunlight for killing bacteria

    International Nuclear Information System (INIS)

    Block, S.S.; Goswami, D.Y.

    1995-01-01

    Solar ultraviolet (UV) photocatalyzed oxidation of chemicals with titanium dioxide (TiO 2 ) has received considerable attention. Much less recognized, however, is the ability of the same system to destroy bacteria. This study examined this phenomenon and the conditions that affect it. Bacteria in aqueous solution were given solar exposure with titanium dioxide and their survival with time was determined. Lamps with a predominantly solar ultraviolet spectrum were also used in the experiments. Without exposure to UV light, TiO 2 had no deleterious effect on the bacteria. However, several common bacteria on solar exposure in the presence of TiO 2 were killed in just a few minutes, whereas without TiO 2 it took over an hour to destroy them. A concentration of 0.01% TiO 2 was most effective in killing bacteria and 10-fold concentrations lower or higher were successively less effective. Inorganic and organic compounds in solution, even in small amounts, interfered with the efficiency of killing. Alkaline solution also reduced the bactericidal activity. Circulation and agitation provided by stirring to keep the TiO 2 particles suspended reduced the time necessary to kill the bacteria. Time-intensity curves for killing bacteria were the same general shape with or without TiO 2 , indicating that TiO 2 served merely as a catalyst to increase the rate of the reaction but that the mechanism of action was not changed. The shape of the curves show that the organisms are sensitized with a minimum intensity of radiation and that an increase doesn't greatly increase the rate of kill. Below this critical intensity, however, the time required for killing markedly increases as the intensity is decreased

  7. Killing superalgebras for Lorentzian four-manifolds

    International Nuclear Information System (INIS)

    Medeiros, Paul de; Figueroa-O’Farrill, José; Santi, Andrea

    2016-01-01

    We determine the Killing superalgebras underpinning field theories with rigid unextended supersymmetry on Lorentzian four-manifolds by re-interpreting them as filtered deformations of ℤ-graded subalgebras with maximum odd dimension of the N=1 Poincaré superalgebra in four dimensions. Part of this calculation involves computing a Spencer cohomology group which, by analogy with a similar result in eleven dimensions, prescribes a notion of Killing spinor, which we identify with the defining condition for bosonic supersymmetric backgrounds of minimal off-shell supergravity in four dimensions. We prove that such Killing spinors always generate a Lie superalgebra, and that this Lie superalgebra is a filtered deformation of a subalgebra of the N=1 Poincaré superalgebra in four dimensions. Demanding the flatness of the connection defining the Killing spinors, we obtain equations satisfied by the maximally supersymmetric backgrounds. We solve these equations, arriving at the classification of maximally supersymmetric backgrounds whose associated Killing superalgebras are precisely the filtered deformations we classify in this paper.

  8. Killing superalgebras for Lorentzian four-manifolds

    Energy Technology Data Exchange (ETDEWEB)

    Medeiros, Paul de [Department of Mathematics and Natural Sciences, University of Stavanger,4036 Stavanger (Norway); Figueroa-O’Farrill, José; Santi, Andrea [Maxwell Institute and School of Mathematics, The University of Edinburgh,James Clerk Maxwell Building, Peter Guthrie Tait Road, Edinburgh EH9 3FD, Scotland (United Kingdom)

    2016-06-20

    We determine the Killing superalgebras underpinning field theories with rigid unextended supersymmetry on Lorentzian four-manifolds by re-interpreting them as filtered deformations of ℤ-graded subalgebras with maximum odd dimension of the N=1 Poincaré superalgebra in four dimensions. Part of this calculation involves computing a Spencer cohomology group which, by analogy with a similar result in eleven dimensions, prescribes a notion of Killing spinor, which we identify with the defining condition for bosonic supersymmetric backgrounds of minimal off-shell supergravity in four dimensions. We prove that such Killing spinors always generate a Lie superalgebra, and that this Lie superalgebra is a filtered deformation of a subalgebra of the N=1 Poincaré superalgebra in four dimensions. Demanding the flatness of the connection defining the Killing spinors, we obtain equations satisfied by the maximally supersymmetric backgrounds. We solve these equations, arriving at the classification of maximally supersymmetric backgrounds whose associated Killing superalgebras are precisely the filtered deformations we classify in this paper.

  9. Female serial killing: review and case report.

    Science.gov (United States)

    Frei, Andreas; Völlm, Birgit; Graf, Marc; Dittmann, Volker

    2006-01-01

    Single homicide committed by women is rare. Serial killing is very infrequent, and the perpetrators are usually white, intelligent males with sadistic tendencies. Serial killing by women has, however, also been described. To conduct a review of published literature on female serial killers and consider its usefulness in assessing a presenting case. A literature review was conducted, after searching EMBASE, MEDLINE and PsycINFO. The presenting clinical case is described in detail in the context of the literature findings. Results The literature search revealed few relevant publications. Attempts to categorize the phenomenon of female serial killing according to patterns of and motives for the homicides have been made by some authors. The most common motive identified was material gain or similar extrinsic gratification while the 'hedonistic' sadistic or sexual serial killer seems to be extremely rare in women. There is no consistent theory of serial killing by women, but psychopathic personality traits and abusive childhood experiences have consistently been observed. The authors' case did not fit the description of a 'typical' female serial killer. In such unusual circumstances as serial killing by a woman, detailed individual case formulation is required to make sense of the psychopathology in each case. Publication of cases in scientific journals should be encouraged to advance our understanding of this phenomenon. Copyright (c) 2006 John Wiley & Sons, Ltd.

  10. 75 FR 62469 - Drawbridge Operation Regulations; Newtown Creek, Dutch Kills, English Kills, and Their...

    Science.gov (United States)

    2010-10-12

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 [Docket No. USCG-2010-0907] Drawbridge Operation Regulations; Newtown Creek, Dutch Kills, English Kills, and Their Tributaries, NY, Maintenance AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY: The Commander...

  11. 75 FR 30299 - Drawbridge Operation Regulations; Newtown Creek, Dutch Kills, English Kills, and Their...

    Science.gov (United States)

    2010-06-01

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 [Docket No. USCG-2010-0355] Drawbridge Operation Regulations; Newtown Creek, Dutch Kills, English Kills, and Their Tributaries, NY, Maintenance AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from regulations. SUMMARY: The Commander...

  12. 9 CFR 113.206 - Wart Vaccine, Killed Virus.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Wart Vaccine, Killed Virus. 113.206... AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Killed Virus Vaccines § 113.206 Wart Vaccine, Killed Virus. Wart Vaccine, Killed Virus, shall be prepared...

  13. 9 CFR 113.213 - Pseudorabies Vaccine, Killed Virus.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Pseudorabies Vaccine, Killed Virus..., DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Killed Virus Vaccines § 113.213 Pseudorabies Vaccine, Killed Virus. Pseudorabies Vaccine, Killed...

  14. 9 CFR 113.209 - Rabies Vaccine, Killed Virus.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Rabies Vaccine, Killed Virus. 113.209... Killed Virus Vaccines § 113.209 Rabies Vaccine, Killed Virus. Rabies Vaccine (Killed Virus) shall be prepared from virus-bearing cell cultures or nerve tissues obtained from animals that have developed rabies...

  15. Effects of polio eradication activities on routine immunization: lessons from the 2013 outbreak response in Somali region of Ethiopia.

    Science.gov (United States)

    Tafesse, Belete; Tekle, Ephrem; Wondwossen, Liya; Bogale, Mengistu; Fiona, Braka; Nsubuga, Peter; Tomas, Karengera; Kassahun, Aron; Kathleen, Gallagher; Teka, Aschalew

    2017-01-01

    Ethiopia experienced several WPV importations with a total of 10 WPV1 cases confirmed during the 2013 outbreak alone before it is closed in 2015. We evaluated supplemental immunization activities (SIAs), including lessons learned for their effect on the routine immunization program during the 2013 polio outbreak in Somali regional state. We used descriptive study to review documents and analyse routine health information system reports from the polio outbreak affected Somali regional state. All data and technical reports of the 15 rounds of polio SIAs from June 2013 through June 2015 and routine immunization coverages for DPT-Hib-HepB 3 and measles were observed. More than 93% of the SIAs were having administrative coverage above 95%. The trend of routine immunization for the two antigens, over the five years (2011 through 2015) did not show a consistent pattern against the number of SIAs. Documentations showed qualitative positive impacts of the SIAs strengthening the routine immunization during all courses of the campaigns. The quantitative impact of polio SIAs on routine immunization remained not so impressive in this study. Clear planning, data consistencies and completeness issues need to be cleared for the impact assessment in quantitative terms, in polio legacy planning as well as for the introduction of injectable polio vaccine through the routine immunization.

  16. Conformal Killing horizons and their thermodynamics

    Science.gov (United States)

    Nielsen, Alex B.; Shoom, Andrey A.

    2018-05-01

    Certain dynamical black hole solutions can be mapped to static spacetimes by conformal metric transformations. This mapping provides a physical link between the conformal Killing horizon of the dynamical black hole and the Killing horizon of the static spacetime. Using the Vaidya spacetime as an example, we show how this conformal relation can be used to derive thermodynamic properties of such dynamical black holes. Although these horizons are defined quasi-locally and can be located by local experiments, they are distinct from other popular notions of quasi-local horizons such as apparent horizons. Thus in the dynamical Vaidya spacetime describing constant accretion of null dust, the conformal Killing horizon, which is null by construction, is the natural horizon to describe the black hole.

  17. "Drone Killings in Principle and in Practice"

    DEFF Research Database (Denmark)

    Dige, Morten

    2017-01-01

    to argue that what we see in the real world cases of drone killings is not merely an accidental or contingent use of drone technology. The real life use reflects to a large extent features that are inherent of the dominant drone systems that has been developed to date. What is being imagined "in principle......" is thus to a large extent drone killings in dreamland. I use an historic example as a point of reference and departure: the debate over the lawfulness of nuclear weapons....

  18. We Left One War and Came to Another: Resource Loss, Acculturative Stress, and Caregiver-Child Relationships in Somali Refugee Families

    Science.gov (United States)

    Betancourt, Theresa S.; Abdi, Saida; Ito, Brandon; Lilienthal, Grace M.; Agalab, Naima; Ellis, Heidi

    2014-01-01

    Background Refugee families often encounter a number of acculturative and resettlement stressors as they make lives for themselves in host countries. These difficulties may be compounded by past trauma and violence exposure posing increased risk for mental health problems. Greater knowledge is needed about protective processes contributing to positive development and adjustment in refugee families despite risk (e.g., resilience). The aims of this research were to identify and examine strengths and resources utilized by Somali refugee children and families in the Boston area to overcome resettlement and acculturative stressors. Methods We used maximum variation sampling to conduct a total of nine focus groups: five focus groups (total participants N=30) among Somali refugee adolescents and youth capturing gender and a range of ages (15-25 years) as well as four focus groups of Somali refugee mothers and fathers in groups (total participants N=32) stratified by gender. Results Drawing from Conservation of Resources Theory (COR), we identified five forms of resources comprising individual, family and collective/community strengths: religious faith; healthy family communication; support networks and peer support. “Community talk” was identified as a community dynamic having both negative and positive implications for family functioning. Conclusions Protective resources among Somali refugee children and families can help to offset acculturative and resettlement stressors. Many of these locally occurring protective resources have the potential to be leveraged by family and community-based interventions. These findings are being used to design preventative interventions that build on local strengths among Somali refugees in the Boston area. PMID:25090142

  19. Pre-pregnancy body mass index and inter-pregnancy weight change among women of Russian, Somali and Kurdish origin and the general Finnish population.

    Science.gov (United States)

    Bastola, Kalpana; Koponen, Päivikki; Härkänen, Tommi; Gissler, Mika; Kinnunen, Tarja I

    2017-05-01

    We studied the differences in the mean pre-pregnancy body mass index (BMI) and mean inter-pregnancy weight change in women of Russian, Somali and Kurdish origin and women in the general Finnish population. The population-based samples were from the Migrant Health and Wellbeing Study and the Health 2011 Survey conducted in six cities in Finland in 2010-2012. This study included women with at least one birth in Finland. Data on their previous pregnancies in Finland were obtained from the National Medical Birth Register for 318 Russian, 584 Somali and 373 Kurdish origin women and for 243 women in the general Finnish population (reference group). Data on pre-pregnancy weight and height were self-reported in early pregnancy. Linear logistic regression was the main method of analysis. The unadjusted mean pre-pregnancy BMI was higher in Somali (27.0 kg/m 2 , p<0.001) and Kurdish (25.8 kg/m 2 , p<0.001) women, but lower in Russian (22.2 kg/m 2 , p<0.001) women than in the reference group (24.1 kg/m 2 ). The adjusted coefficients for the difference in the mean pre-pregnancy BMI were -1.93 (95% CI -2.77 to -1.09) for Russian, 1.82 (95% CI 0.89-2.75) for Somali and 1.30 (95% CI 0.43-2.17) for Kurdish women compared with the reference group. Among women with at least two births, no statistically significant difference was observed in the mean inter-pregnancy weight change between the migrant groups and the reference group. Somali and Kurdish women had higher mean pre-pregnancy BMIs than women in the general Finnish population and may need special support and health promotion strategies for weight management.

  20. Killing Hitler: A Writer's Journey and Angst.

    Science.gov (United States)

    Thaler, Paul

    2002-01-01

    Describes the author's experiences in preparing a talk that "evokes the specter" of Adolf Hitler and in writing an historical account of a British plot to kill Hitler. Address the question of why the British allowed him to live that final year of the war. Muses on why scholars write, and the impact of violence and terrorism. (SG)

  1. Integrating Poetry and "To Kill a Mockingbird."

    Science.gov (United States)

    Jolley, Susan Arpajian

    2002-01-01

    Outlines a method of teaching "To Kill a Mockingbird" along with the study of poetry. Notes that this method allows students to consider the themes of courage and developing compassion. Concludes that teaching such a multigenre unit allows students to look for connections among fact and fiction, the past and present, their own lives and…

  2. School Shootings; Standards Kill Students and Society

    Science.gov (United States)

    Angert, Betsy L.

    2008-01-01

    School shootings have been in the news of late. People ponder what occurs in classrooms today. Why would a young person wish to take a life? Within educational institutions, the killings are a concern. In our dire attempt to teach the children and ensure student success, it seems many of our offspring are lost. Some students feel separate from…

  3. Mass killings and detection of impacts

    Science.gov (United States)

    McLaren, Digby J.

    Highly energetic bolide impacts occur and their flux is known. For larger bodies the energy release is greater than for any other short-term global phenomenon. Such impacts produce or release a large variety of shock induced changes including major atmospheric, sedimentologic, seismic and volcanic events. These events must necessarily leave a variety of records in the stratigraphic column, including mass killings resulting in major changes in population density and reduction or extinction of many taxonomic groups, followed by characteristic patterns of faunal and flora replacement. Of these effects, mass killings, marked by large-scale loss of biomass, are the most easily detected evidence in the field but must be manifest on a near-global scale. Such mass killings that appear to be approximately synchronous and involve disappearance of biomass at a bedding plane in many sedimentologically independent sections globally suggest a common cause and probable synchroneity. Mass killings identify an horizon which may be examined for evidence of cause. Geochemical markers may be ephemeral and absence may not be significant. There appears to be no reason why ongoing phenomena such as climate and sea-level changes are primary causes of anomolous episodic events.

  4. Contagion in Mass Killings and School Shootings.

    Directory of Open Access Journals (Sweden)

    Sherry Towers

    Full Text Available Several past studies have found that media reports of suicides and homicides appear to subsequently increase the incidence of similar events in the community, apparently due to the coverage planting the seeds of ideation in at-risk individuals to commit similar acts.Here we explore whether or not contagion is evident in more high-profile incidents, such as school shootings and mass killings (incidents with four or more people killed. We fit a contagion model to recent data sets related to such incidents in the US, with terms that take into account the fact that a school shooting or mass murder may temporarily increase the probability of a similar event in the immediate future, by assuming an exponential decay in contagiousness after an event.We find significant evidence that mass killings involving firearms are incented by similar events in the immediate past. On average, this temporary increase in probability lasts 13 days, and each incident incites at least 0.30 new incidents (p = 0.0015. We also find significant evidence of contagion in school shootings, for which an incident is contagious for an average of 13 days, and incites an average of at least 0.22 new incidents (p = 0.0001. All p-values are assessed based on a likelihood ratio test comparing the likelihood of a contagion model to that of a null model with no contagion. On average, mass killings involving firearms occur approximately every two weeks in the US, while school shootings occur on average monthly. We find that state prevalence of firearm ownership is significantly associated with the state incidence of mass killings with firearms, school shootings, and mass shootings.

  5. Contagion in Mass Killings and School Shootings.

    Science.gov (United States)

    Towers, Sherry; Gomez-Lievano, Andres; Khan, Maryam; Mubayi, Anuj; Castillo-Chavez, Carlos

    2015-01-01

    Several past studies have found that media reports of suicides and homicides appear to subsequently increase the incidence of similar events in the community, apparently due to the coverage planting the seeds of ideation in at-risk individuals to commit similar acts. Here we explore whether or not contagion is evident in more high-profile incidents, such as school shootings and mass killings (incidents with four or more people killed). We fit a contagion model to recent data sets related to such incidents in the US, with terms that take into account the fact that a school shooting or mass murder may temporarily increase the probability of a similar event in the immediate future, by assuming an exponential decay in contagiousness after an event. We find significant evidence that mass killings involving firearms are incented by similar events in the immediate past. On average, this temporary increase in probability lasts 13 days, and each incident incites at least 0.30 new incidents (p = 0.0015). We also find significant evidence of contagion in school shootings, for which an incident is contagious for an average of 13 days, and incites an average of at least 0.22 new incidents (p = 0.0001). All p-values are assessed based on a likelihood ratio test comparing the likelihood of a contagion model to that of a null model with no contagion. On average, mass killings involving firearms occur approximately every two weeks in the US, while school shootings occur on average monthly. We find that state prevalence of firearm ownership is significantly associated with the state incidence of mass killings with firearms, school shootings, and mass shootings.

  6. Breast-feeding and complementary feeding practices in the first 6 months of life among Norwegian-Somali and Norwegian-Iraqi infants: the InnBaKost survey.

    Science.gov (United States)

    Grewal, Navnit Kaur; Andersen, Lene Frost; Sellen, Daniel; Mosdøl, Annhild; Torheim, Liv Elin

    2016-03-01

    To examine breast-feeding and complementary feeding practices during the first 6 months of life among Norwegian infants of Somali and Iraqi family origin. A cross-sectional survey was performed during March 2013-February 2014. Data were collected using a semi-quantitative FFQ adapted from the second Norwegian national dietary survey among infants in 2006-2007. Somali-born and Iraqi-born mothers living in eastern Norway were invited to participate. One hundred and seven mothers/infants of Somali origin and eighty mothers/infants of Iraqi origin participated. Breast-feeding was almost universally initiated after birth. Only 7 % of Norwegian-Somali and 10 % of Norwegian-Iraqi infants were exclusively breast-fed at 4 months of age. By 1 month of age, water had been introduced to 30 % of Norwegian-Somali and 26 % of Norwegian-Iraqi infants, and infant formula to 44 % and 34 %, respectively. Fifty-four per cent of Norwegian-Somali and 68 % of Norwegian-Iraqi infants had been introduced to solid or semi-solid foods at 4 months of age. Breast-feeding at 6 months of age was more common among Norwegian-Somali infants (79 %) compared with Norwegian-Iraqi infants (58 %; P=0·001). Multivariate analyses indicated no significant factors associated with exclusive breast-feeding at 3·5 months of age. Factors positively associated with breast-feeding at 6 months were country of origin (Somalia) and parity (>2). Breast-feeding initiation was common among Iraqi-born and Somali-born mothers, but the exclusive breast-feeding period was shorter than recommended in both groups. The study suggests that there is a need for new culture-specific approaches to support exclusive breast-feeding and complementary feeding practices among foreign-born mothers living in Norway.

  7. Dirac operators and Killing spinors with torsion; Dirac-Operatoren und Killing-Spinoren mit Torsion

    Energy Technology Data Exchange (ETDEWEB)

    Becker-Bender, Julia

    2012-12-17

    On a Riemannian spin manifold with parallel skew torsion, we use the twistor operator to obtain an eigenvalue estimate for the Dirac operator with torsion. We consider the equality case in dimensions four and six. In odd dimensions we describe Sasaki manifolds on which equality in the estimate is realized by Killing spinors with torsion. In dimension five we characterize all Killing spinors with torsion and obtain certain naturally reductive spaces as exceptional cases.

  8. Culturally adapting a physical activity intervention for Somali women: the need for theory and innovation to promote equity.

    Science.gov (United States)

    Murray, Kate E; Ermias, Azieb; Lung, Amber; Mohamed, Amina Sheik; Ellis, B Heidi; Linke, Sarah; Kerr, Jacqueline; Bowen, Deborah J; Marcus, Bess H

    2017-03-01

    There is pressing need for innovation in clinical research to more effectively recruit, engage, retain, and promote health among diverse populations overburdened by health disparities. The purpose of this study is to provide a detailed illustration of the cultural adaptation of an evidence-based intervention to bolster translational research with currently underserved communities. The cultural adaptation heuristic framework described by Barrera and colleagues is applied to the adaptation of a physical activity evidence-based intervention with adult Somali women. Widespread changes were required to ensure program feasibility and acceptability, including the reduction of assessment protocols and changes discordant with current trends in physical activity research. The cultural adaptation of evidence-based interventions offers an important mechanism for reducing health disparities. Improved reporting standards, assessment of features relevant to underserved communities, and greater funding requirements to ensure better representation are needed to promote more widespread access for all people.

  9. Bacterial Killing by Dry Metallic Copper Surfaces▿

    OpenAIRE

    Santo, Christophe Espírito; Lam, Ee Wen; Elowsky, Christian G.; Quaranta, Davide; Domaille, Dylan W.; Chang, Christopher J.; Grass, Gregor

    2010-01-01

    Metallic copper surfaces rapidly and efficiently kill bacteria. Cells exposed to copper surfaces accumulated large amounts of copper ions, and this copper uptake was faster from dry copper than from moist copper. Cells suffered extensive membrane damage within minutes of exposure to dry copper. Further, cells removed from copper showed loss of cell integrity. Acute contact with metallic copper surfaces did not result in increased mutation rates or DNA lesions. These findings are important fir...

  10. It's not just conflict that motivates killing of orangutans.

    Directory of Open Access Journals (Sweden)

    Jacqueline T Davis

    Full Text Available We investigated why orangutans are being killed in Kalimantan, Indonesia, and the role of conflict in these killings. Based on an analysis of interview data from over 5,000 respondents in over 450 villages, we also assessed the socio-ecological factors associated with conflict and non-conflict killings. Most respondents never kill orangutans. Those who reported having personally killed an orangutan primarily did so for non-conflict reasons; for example, 56% of these respondents said that the reason they had killed an orangutan was to eat it. Of the conflict-related reasons for killing, the most common reasons orangutans were killed was fear of orangutans or in self-defence. A similar pattern was evident among reports of orangutan killing by other people in the villages. Regression analyses indicated that religion and the percentage of intact forest around villages were the strongest socio-ecological predictors of whether orangutans were killed for conflict or non-conflict related reasons. Our data indicate that between 44,170 and 66,570 orangutans were killed in Kalimantan within the respondents' active hunting lifetimes: between 12,690 and 29,024 for conflict reasons (95%CI and between 26,361 and 41,688 for non-conflict reasons (95% CI. These findings confirm that habitat protection alone will not ensure the survival of orangutans in Indonesian Borneo, and that effective reduction of orangutan killings is urgently needed.

  11. It's not just conflict that motivates killing of orangutans.

    Science.gov (United States)

    Davis, Jacqueline T; Mengersen, Kerrie; Abram, Nicola K; Ancrenaz, Marc; Wells, Jessie A; Meijaard, Erik

    2013-01-01

    We investigated why orangutans are being killed in Kalimantan, Indonesia, and the role of conflict in these killings. Based on an analysis of interview data from over 5,000 respondents in over 450 villages, we also assessed the socio-ecological factors associated with conflict and non-conflict killings. Most respondents never kill orangutans. Those who reported having personally killed an orangutan primarily did so for non-conflict reasons; for example, 56% of these respondents said that the reason they had killed an orangutan was to eat it. Of the conflict-related reasons for killing, the most common reasons orangutans were killed was fear of orangutans or in self-defence. A similar pattern was evident among reports of orangutan killing by other people in the villages. Regression analyses indicated that religion and the percentage of intact forest around villages were the strongest socio-ecological predictors of whether orangutans were killed for conflict or non-conflict related reasons. Our data indicate that between 44,170 and 66,570 orangutans were killed in Kalimantan within the respondents' active hunting lifetimes: between 12,690 and 29,024 for conflict reasons (95%CI) and between 26,361 and 41,688 for non-conflict reasons (95% CI). These findings confirm that habitat protection alone will not ensure the survival of orangutans in Indonesian Borneo, and that effective reduction of orangutan killings is urgently needed.

  12. 9 CFR 113.201 - Canine Distemper Vaccine, Killed Virus.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Canine Distemper Vaccine, Killed Virus... REQUIREMENTS Killed Virus Vaccines § 113.201 Canine Distemper Vaccine, Killed Virus. Canine Distemper Vaccine... canine distemper susceptible dogs (20 vaccinates and 5 controls) shall be used as test animals. Blood...

  13. 9 CFR 113.208 - Avian Encephalomyelitis Vaccine, Killed Virus.

    Science.gov (United States)

    2010-01-01

    ..., Killed Virus. 113.208 Section 113.208 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Killed Virus Vaccines § 113.208 Avian Encephalomyelitis Vaccine, Killed Virus. Avian...

  14. 9 CFR 113.204 - Mink Enteritis Vaccine, Killed Virus.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Mink Enteritis Vaccine, Killed Virus..., DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Killed Virus Vaccines § 113.204 Mink Enteritis Vaccine, Killed Virus. Mink Enteritis Vaccine...

  15. 9 CFR 113.212 - Bursal Disease Vaccine, Killed Virus.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Bursal Disease Vaccine, Killed Virus..., DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Killed Virus Vaccines § 113.212 Bursal Disease Vaccine, Killed Virus. Bursal Disease Vaccine...

  16. Road-Killed Animals as Resources for Ecological Studies.

    Science.gov (United States)

    Adams, Clark E.

    1983-01-01

    Summarizes 19 literature sources identifying road-killed vertebrates and frequency of kill by numbers. Examples of how these animals can be incorporated into curricula (integrating biology, society, people, and values) are given, followed by an illustrated example of how a road-killed raccoon's skull demonstrated a human/wildlife interaction prior…

  17. Killing vectors in empty space algebraically special metrics. II

    International Nuclear Information System (INIS)

    Held, A.

    1976-01-01

    Empty space algebraically special metrics possessing an expanding degenerate principal null vector and Killing vectors are investigated. Attention is centered on that class of Killing vector (called nonpreferred) which is necessarily spacelike in the asymptotic region. A detailed analysis of the relationship between the Petrov--Penrose classification and these Killing vectors is carried out

  18. Gli italo-somali dell’Amministrazione Fiduciaria Italiana della Somalia (AFIS: una memoria dimenticata tra le pagine dell’Italia postcoloniale

    Directory of Open Access Journals (Sweden)

    Michele Pandolfo

    2017-07-01

    Full Text Available At the end of the Second World War the United Nations gave to Italy a special protectorate on the own former colony by the International Trusteeship System of Somalia, which concludes in 1960. During the Fifties there are many relationships between the italian men and the somali women: from these liaisons there are a lot of children which have different destinies and their history represents one of the heredity of the italian past in Africa. From this italo-somali métissage, rises an association who asks the recognition of all the pains suffered by a part of that community and in the same time it asks a collective reflections of the historic memories about the Trusteeship System.

  19. La piratería de Nigeria como una amenaza a la seguridad marítima del Golfo de Guinea (2007-2012). Una aproximación desde el crimen organizado

    OpenAIRE

    Valderrama Luna, Lina María

    2015-01-01

    Desde finales de los 70 la piratería se convirtió en un problema para Nigeria. Con el tiempo adquirió características del crimen organizado y en 2010 se transformó en un problema transnacional, afectando a Estados del golfo de Guinea. Así, a través de una base conceptual, el estudio de caso concluyó que los factores internos –como la pobreza, debilidad estatal y marginalización- y externos –siendo ellos la falta de políticas internas destinadas a las aguas y la ausencia de estrategias marítim...

  20. Intrinsic structural variation of the complex microsatellite marker MYCL1 in Finnish and Somali populations and its relevance to gastrointestinal tumors

    Directory of Open Access Journals (Sweden)

    Hanna Vauhkonen

    2006-01-01

    Full Text Available The structurally complex MYCL1 microsatellite marker is often used to determine microsatellite instability in colorectal cancers but the allelic variation of this marker has remained largely uncharacterized in both populations and in cancers. Our study describes the allelic distributions of MYCL1 in Finnish (n = 117 and Somali population samples (n = 61 of non-related individuals and compares this distribution with the instability pattern obtained from 61 gastrointestinal tumors.

  1. 'The child that tiire doesn't give you, God won't give you either.' The role of Rotheca myricoides in Somali fertility practices.

    Science.gov (United States)

    Mire, Sada

    2016-12-01

    The paper introduces the Baanashada Dumarka, a Somali fertility therapy carried out by a spirit medium, known locally as 'Alaqad. Baanashada is aimed at women whose fertility issues are believed to be caused by spirits. The study also explores a component of the Baanashada, namely, the use of tiire (Rotheca myricoides), or the butterfly bush. Although Rotheca myricoides is known to possess a number of medicinal components as confirmed by studies of modern science, so far, there exist no studies on its potential (or lack of) fertility effects. Hence, the alleged fertility benefits of the butterfly bush need examining. In 2008 a British Somali woman died of herbs placed in her cervix by a traditional healer in Somaliland. This piece of information indicated not only the role of herbal medicine in fertility practices, but also the popularity of traditional reproductive medicine beyond border, class or educational background. Yet, current research into Somali women's health focuses mainly on Female Genital Mutilation (FGM), examined often without the context of wider cultural practices. This paper, however, suggests that rituals, beliefs and material culture play a paramount role in women's practices. For example, as explored elsewhere, the wagar, a wooden and sacred object made of the African olive, is critical for fertility practices. The current paper illuminates further the significance of reproduction practices in Somali society and the potential continuity of traditions associated with the perpetuation of kinship. It concludes that fertility rituals are part of a wider context of interaction with sacred landscapes, objects and archaeological sites, often associated with past legends in the Horn of Africa.

  2. Comparison of manual and automated AmpliSeq™ workflows in the typing of a Somali population with the Precision ID Identity Panel.

    Science.gov (United States)

    van der Heijden, Suzanne; de Oliveira, Susanne Juel; Kampmann, Marie-Louise; Børsting, Claus; Morling, Niels

    2017-11-01

    The Precision ID Identity Panel was used to type 109 Somali individuals in order to obtain allele frequencies for the Somali population. These frequencies were used to establish a Somali HID-SNP database, which will be used for the biostatistic calculations in family and immigration cases. Genotypes obtained with the Precision ID Identity Panel were found to be almost in complete concordance with genotypes obtained with the SNPforID PCR-SBE-CE assay. In seven SNP loci, silent alleles were identified, of which most were previously described in the literature. The project also set out to compare different AmpliSeq™ workflows to investigate the possibility of using automated library building in forensic genetic case work. In order to do so, the SNP typing of the Somalis was performed using three different workflows: 1) manual library building and sequencing on the Ion PGM™, 2) automated library building using the Biomek ® 3000 and sequencing on the Ion PGM™, and 3) automated library building using the Ion Chef™ and sequencing on the Ion S5™. AmpliSeq™ workflows were compared based on coverage, locus balance, noise, and heterozygote balance. Overall, the Ion Chef™/Ion S5™ workflow was found to give the best results and required least hands-on time in the laboratory. However, the Ion Chef™/Ion S5™ workflow was also the most expensive. The number of libraries that may be constructed in one Ion Chef™ library building run was limited to eight, which is too little for high throughput workflows. The Biomek ® 3000/Ion PGM™ workflow was found to perform similarly to the manual/Ion PGM™ workflow. This argues for the use of automated library building in forensic genetic case work. Automated library building decreases the workload of the laboratory staff, decreases the risk of pipetting errors, and simplifies the daily workflow in forensic genetic laboratories. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Pseudofaults and associated seamounts in the conjugate Arabian and Eastern Somali basins, NW Indian Ocean - New constraints from high-resolution satellite-derived gravity data

    Science.gov (United States)

    Sreejith, K. M.; Chaubey, A. K.; Mishra, Akhil; Kumar, Shravan; Rajawat, A. S.

    2016-12-01

    Marine gravity data derived from satellite altimeters are effective tools in mapping fine-scale tectonic features of the ocean basins such as pseudofaults, fracture zones and seamounts, particularly when the ocean basins are carpeted with thick sediments. We use high-resolution satellite-generated gravity and seismic reflection data to map boundaries of pseudofaults and transferred crust related to the Paleocene spreading ridge propagation in the Arabian and its conjugate Eastern Somali basins. The study has provided refinement in the position of previously reported pseudofaults and their spatial extensions in the conjugate basins. It is observed that the transferred crustal block bounded by inner pseudofault and failed spreading ridge is characterized by a gravity low and rugged basement. The refined satellite gravity image of the Arabian Basin also revealed three seamounts in close proximity to the pseudofaults, which were not reported earlier. In the Eastern Somali Basin, seamounts are aligned along NE-SW direction forming ∼300 km long seamount chain. Admittance analysis and Flexural model studies indicated that the seamount chain is isostatically compensated locally with Effective Elastic Thickness (Te) of 3-4 km. Based on the present results and published plate tectonic models, we interpret that the seamounts in the Arabian Basin are formed by spreading ridge propagation and are associated with pseudofaults, whereas the seamount chain in the Eastern Somali Basin might have probably originated due to melting and upwelling of upper mantle heterogeneities in advance of migrating/propagating paleo Carlsberg Ridge.

  4. Counter-piracy

    DEFF Research Database (Denmark)

    Feldtmann, Birgit

    2017-01-01

    In May 2010, various media reported that a Russian naval vessel had seized a group of Somali pirates after they allegedly had tried to attack a Russian-owned vessel. According to the reports, the pirates were, due to a ‘lack of legal basis’, ‘released’ from custody in a small boat without means...

  5. Roman Lyariev, How to Skin Your Kill

    OpenAIRE

    Gedeeva, Darina; Ubushieva, Bamba; Babaev, Andrei

    2016-01-01

    Roman explains how to skin a fox. First, one needs to prepare the ground by trampling it. Skinning should be done with a small sharp knife. A freshly killed fox skins easily. Then one needs to treat the skin with an anti-flea spray. At home the skin should be stretched on a triangular wooden panel called in Russian pravilka and left in a dry room for up to five days. People usually go hunting when foxes are on heat and are busy fighting with each other for females. When the wind is strong, fo...

  6. Micro-sociology of mass rampage killings.

    Science.gov (United States)

    Collins, Randall

    2014-01-01

    Spectacular but very rare violent events such as mass killings by habitual non-criminals cannot be explained by factors which are very widespread, such as possession of firearms, being a victim of bullying, an introvert, or a career failure. A stronger clue is clandestine preparation of attack by one or two individuals, against randomly chosen representatives of a hated collective identity. Mass killers develop a deep back-stage, obsessed with planning their attack, overcoming social inferiority and isolation by an emotion of clandestine excitement.

  7. Designing Antibacterial Peptides with Enhanced Killing Kinetics

    Directory of Open Access Journals (Sweden)

    Faiza H. Waghu

    2018-02-01

    Full Text Available Antimicrobial peptides (AMPs are gaining attention as substitutes for antibiotics in order to combat the risk posed by multi-drug resistant pathogens. Several research groups are engaged in design of potent anti-infective agents using natural AMPs as templates. In this study, a library of peptides with high sequence similarity to Myeloid Antimicrobial Peptide (MAP family were screened using popular online prediction algorithms. These peptide variants were designed in a manner to retain the conserved residues within the MAP family. The prediction algorithms were found to effectively classify peptides based on their antimicrobial nature. In order to improve the activity of the identified peptides, molecular dynamics (MD simulations, using bilayer and micellar systems could be used to design and predict effect of residue substitution on membranes of microbial and mammalian cells. The inference from MD simulation studies well corroborated with the wet-lab observations indicating that MD-guided rational design could lead to discovery of potent AMPs. The effect of the residue substitution on membrane activity was studied in greater detail using killing kinetic analysis. Killing kinetics studies on Gram-positive, negative and human erythrocytes indicated that a single residue change has a drastic effect on the potency of AMPs. An interesting outcome was a switch from monophasic to biphasic death rate constant of Staphylococcus aureus due to a single residue mutation in the peptide.

  8. The 1990 Arthur Kill oil spills

    International Nuclear Information System (INIS)

    Astor, P.H.

    1990-01-01

    On January 1-2, 1990, Exxon discharged 567,000 gallons of No. 2 heating oil in the Arthur Kill, the strait separating Staten Island, New York from New Jersey. Lawsuits against Exxon were filed by the State of New Jersey, New York City, and the City of Elizabeth. They seek to force Exxon to reimburse the municipalities and the state for cleanup costs and to restore damaged wetlands and other natural resources. The three plaintiffs, joined by New York State and the federal government, initiated a three-tiered natural resource damage assessment study (Tier II), currently underway, includes sampling and chemical analysis of sediments and benthic invertebrates, mapping of impacted wetlands and measurement of direct impacts on water birds and their prey. The purposes of the study are to quantify the damages and determine the presence of Exxon's oil in the sediments. Since the Exxon spill, there have been two major spills and an intermediate-size spill. During the first size months of 1990, over one million gallons of petroleum products have been discharged into the Arthur Kill and nearby waters. This paper reports that a review of these incidents provides lessons for the prevention, investigation, and cleanup of spills in urban estuaries

  9. Where and How Wolves (Canis lupus Kill Beavers (Castor canadensis.

    Directory of Open Access Journals (Sweden)

    Thomas D Gable

    Full Text Available Beavers (Castor canadensis can be a significant prey item for wolves (Canis lupus in boreal ecosystems due to their abundance and vulnerability on land. How wolves hunt beavers in these systems is largely unknown, however, because observing predation is challenging. We inferred how wolves hunt beavers by identifying kill sites using clusters of locations from GPS-collared wolves in Voyageurs National Park, Minnesota. We identified 22 sites where wolves from 4 different packs killed beavers. We classified these kill sites into 8 categories based on the beaver-habitat type near which each kill occurred. Seasonal variation existed in types of kill sites as 7 of 12 (58% kills in the spring occurred at sites below dams and on shorelines, and 8 of 10 (80% kills in the fall occurred near feeding trails and canals. From these kill sites we deduced that the typical hunting strategy has 3 components: 1 waiting near areas of high beaver use (e.g., feeding trails until a beaver comes near shore or ashore, 2 using vegetation, the dam, or other habitat features for concealment, and 3 immediately attacking the beaver, or ambushing the beaver by cutting off access to water. By identifying kill sites and inferring hunting behavior we have provided the most complete description available of how and where wolves hunt and kill beavers.

  10. Heterosigma bloom and associated fish kill

    Science.gov (United States)

    Hershberger, P.K.; Rensel, J.E.; Postel, J.R.; Taub, F.B.

    1997-01-01

    A bloom of the harmful marine phytoplankton, Heterosigma carterae occurred in upper Case Inlet, south Puget Sound, Washington in late September, 1994, correlating with the presence of at least 35 dead salmon. This marks the first time that this alga has been closely correlated with a wild fish kill; in the past it was thought to be associated with kills of penned fish at fish farms only. We were informed of the presence of a possible harmful algal bloom and dead salinois Ilear the town of Allyn on 27 September and a team was formed to investigate. We arrived at the Allyn waterfront at 17:30 hours the same day. Prior to our arrival, state agency personnel walked approximatcly two miles of shoreline from the powerlines north of the dock, to the mouth of Sherwood Creek and conducted the only official count of dead fish present along the shore consisting of 12 coho salmon (Oncorhynchus kisutch), 11 chum salmon (Oncorhynchus keta), 12 chinook salmon (Oncorhynchus tschawytscha), one flat fish, and one sculpin on the morning of 9/27. Since previous harmful blooms of Heterosigma have resultedin the majority of net penreared salmon sinking to the bottom of pens, and only approximately two miles of shoreline were sampled, it is suspected that many more exposed fish may have succumbed than were counted. Witnesses who explored the east side of the bay reported seeing many dead salmon there as well, but no counts were made. State agency personnel who observed the fish kill reported seeing “dying fish coming to the beach, gulping at the surface, trying to get out of the water” Scavengers were seen consuming the salmon carcasses; these included two harbor seals, a house cat, and Hymenopteran insects. None suffered any noticeable acute ill effects. Although precise cause of death has not been ascertained, visual inspection of the reproductive organs from a deceased male chum salmon found on the shore at Allyn confirmed that the fish was not yet reproductively mature and

  11. Conformal Killing vectors in Robertson-Walker spacetimes

    International Nuclear Information System (INIS)

    Maartens, R.; Maharaj, S.d.

    1986-01-01

    It is well known that Robertson-Walker spacetimes admit a conformal Killingl vector normal to the spacelike homogeneous hypersurfaces. Because these spacetimes are conformally flat, there are a further eight conformal Killing vectors, which are neither normal nor tangent to the homogeneous hypersurfaces. The authors find these further conformal Killing vectors and the Lie algebra of the full G 15 of conformal motions. Conditions on the metric scale factor are determined which reduce some of the conformal Killing vectors to homothetic Killing vectors or Killing vectors, allowing one to regain in a unified way the known special geometries. The non-normal conformal Killing vectors provide a counter-example to show that conformal motions do not, in general, map a fluid flow conformally. These non-normal vectors are also used to find the general solution of the null geodesic equation and photon Liouville equation. (author)

  12. The eyeball killer: serial killings with postmortem globe enucleation.

    Science.gov (United States)

    Coyle, Julie; Ross, Karen F; Barnard, Jeffrey J; Peacock, Elizabeth; Linch, Charles A; Prahlow, Joseph A

    2015-05-01

    Although serial killings are relatively rare, they can be the cause of a great deal of anxiety while the killer remains at-large. Despite the fact that the motivations for serial killings are typically quite complex, the psychological analysis of a serial killer can provide valuable insight into how and why certain individuals become serial killers. Such knowledge may be instrumental in preventing future serial killings or in solving ongoing cases. In certain serial killings, the various incidents have a variety of similar features. Identification of similarities between separate homicidal incidents is necessary to recognize that a serial killer may be actively killing. In this report, the authors present a group of serial killings involving three prostitutes who were shot to death over a 3-month period. Scene and autopsy findings, including the unusual finding of postmortem enucleation of the eyes, led investigators to recognize the serial nature of the homicides. © 2015 American Academy of Forensic Sciences.

  13. Monoclonal TCR-redirected tumor cell killing.

    Science.gov (United States)

    Liddy, Nathaniel; Bossi, Giovanna; Adams, Katherine J; Lissina, Anna; Mahon, Tara M; Hassan, Namir J; Gavarret, Jessie; Bianchi, Frayne C; Pumphrey, Nicholas J; Ladell, Kristin; Gostick, Emma; Sewell, Andrew K; Lissin, Nikolai M; Harwood, Naomi E; Molloy, Peter E; Li, Yi; Cameron, Brian J; Sami, Malkit; Baston, Emma E; Todorov, Penio T; Paston, Samantha J; Dennis, Rebecca E; Harper, Jane V; Dunn, Steve M; Ashfield, Rebecca; Johnson, Andy; McGrath, Yvonne; Plesa, Gabriela; June, Carl H; Kalos, Michael; Price, David A; Vuidepot, Annelise; Williams, Daniel D; Sutton, Deborah H; Jakobsen, Bent K

    2012-06-01

    T cell immunity can potentially eradicate malignant cells and lead to clinical remission in a minority of patients with cancer. In the majority of these individuals, however, there is a failure of the specific T cell receptor (TCR)–mediated immune recognition and activation process. Here we describe the engineering and characterization of new reagents termed immune-mobilizing monoclonal TCRs against cancer (ImmTACs). Four such ImmTACs, each comprising a distinct tumor-associated epitope-specific monoclonal TCR with picomolar affinity fused to a humanized cluster of differentiation 3 (CD3)-specific single-chain antibody fragment (scFv), effectively redirected T cells to kill cancer cells expressing extremely low surface epitope densities. Furthermore, these reagents potently suppressed tumor growth in vivo. Thus, ImmTACs overcome immune tolerance to cancer and represent a new approach to tumor immunotherapy.

  14. Killing vectors in algebraically special space-times

    International Nuclear Information System (INIS)

    Torres del Castillo, G.F.

    1984-01-01

    The form of the isometric, homothetic, and conformal Killing vectors for algebraically special metrics which admit a shear-free congruence of null geodesics is obtained by considering their complexification, using the existence of a congruence of null strings. The Killing equations are partially integrated and the reasons which permit this reduction are exhibited. In the case where the congruence of null strings has a vanishing expansion, the Killing equations are reduced to a single master equation

  15. Spacelike conformal Killing vectors and spacelike congruences

    International Nuclear Information System (INIS)

    Mason, D.P.; Tsamparlis, M.

    1985-01-01

    Necessary and sufficient conditions are derived for space-time to admit a spacelike conformal motion with symmetry vector parallel to a unit spacelike vector field n/sup a/. These conditions are expressed in terms of the shear and expansion of the spacelike congruence generated by n/sup a/ and in terms of the four-velocity of the observer employed at any given point of the congruence. It is shown that either the expansion or the rotation of this spacelike congruence must vanish if Dn/sup a//dp = 0, where p denotes arc length measured along the integral curves of n/sup a/, and also that there exist no proper spacelike homothetic motions with constant expansion. Propagation equations for the projection tensor and the rotation tensor are derived and it is proved that every isometric spacelike congruence is rigid. Fluid space-times are studied in detail. A relation is established between spacelike conformal motions and material curves in the fluid: if a fluid space-time admits a spacelike conformal Killing vector parallel to n/sup a/ and n/sub a/u/sup a/ = 0, where u/sup a/ is the fluid four-velocity, then the integral curves of n/sup a/ are material curves in an irrotational fluid, while if the fluid vorticity is nonzero, then the integral curves of n/sup a/ are material curves if and only if they are vortex lines. An alternative derivation, based on the theory of spacelike congruences, of some of the results of Collins [J. Math. Phys. 25, 995 (1984)] on conformal Killing vectors parallel to the local vorticity vector in shear-free perfect fluids with zero magnetic Weyl tensor is given

  16. Initiating a different story about immigrant Somali parents’ support of their primary school children’s education

    Directory of Open Access Journals (Sweden)

    Doria Daniels

    2017-08-01

    Full Text Available The ability of parents to nurture and support their children during their primary school years is considered to be fundamental for the child’s development and learning. Teachers and educational psychologists assign great prominence to parental involvement as a tool to advance educational success for children, especially for those who are faced with disadvantages. In the past two decades, we have seen South African schools radically shifting from being racially and ethnically homogenous to becoming culturally, ethnically and linguistically heterogeneous. It is especially the schools in the lower socioeconomic areas that find themselves under tremendous pressure to serve their growing immigrant school population. Not enough is known about the cultural capital that lies embedded in these learners’ home contexts and the roles that their parents play in their education. In this manuscript, I investigate the potential intersectionality of school and home and critique the affiliation between teachers and immigrant parents as an important dimension of learning success in the primary school. I situate the discussion in a community school with a strong Somali immigrant population.

  17. The Impact of Food Consumption, Government Type and Effectiveness, on the Rate of Somali Maritime Piracy, 2000-2008

    Directory of Open Access Journals (Sweden)

    Sam Rohrer

    2011-10-01

    Full Text Available The analysis of maritime piracy off the Horn of Africa is still a developing area of academic research. The work that has been conducted to date has remained largely qualitative.   Two recurring assumptions made but not empirically tested in this area of research are 1 the perceived link between government stability and the rate of maritime piracy, and 2 drought conditions implying food shortages in Somalia, and their impact on the rate of maritime piracy off the Horn of Africa.  The findings of this project show a strong increase in maritime piracy following the transition from assorted Islamic Courts to the Transitional Federal Government (TFG.  However, variations in the consumption of staple foodstuffs, and an index of the World Bank Governance Indicators do not have a significant impact on the frequency of maritime piracy in the region.  If maritime piracy off the Somali coast is to be eliminated, rather than policed, efforts should be made to encourage the development of governmental institutions that utilize culturally-respected institutions supported by the local populace.

  18. Antibacterial activity of silver-killed bacteria: the "zombies" effect

    Science.gov (United States)

    Wakshlak, Racheli Ben-Knaz; Pedahzur, Rami; Avnir, David

    2015-04-01

    We report a previously unrecognized mechanism for the prolonged action of biocidal agents, which we denote as the zombies effect: biocidally-killed bacteria are capable of killing living bacteria. The concept is demonstrated by first killing Pseudomonas aeruginosa PAO1 with silver nitrate and then challenging, with the dead bacteria, a viable culture of the same bacterium: Efficient antibacterial activity of the killed bacteria is observed. A mechanism is suggested in terms of the action of the dead bacteria as a reservoir of silver, which, due to Le-Chatelier's principle, is re-targeted to the living bacteria. Langmuirian behavior, as well as deviations from it, support the proposed mechanism.

  19. Killing spinors as a characterisation of rotating black hole spacetimes

    International Nuclear Information System (INIS)

    Cole, Michael J; Kroon, Juan A Valiente

    2016-01-01

    We investigate the implications of the existence of Killing spinors in a spacetime. In particular, we show that in vacuum and electrovacuum a Killing spinor, along with some assumptions on the associated Killing vector in an asymptotic region, guarantees that the spacetime is locally isometric to the Kerr or Kerr–Newman solutions. We show that the characterisation of these spacetimes in terms of Killing spinors is an alternative expression of characterisation results of Mars (Kerr) and Wong (Kerr–Newman) involving restrictions on the Weyl curvature and matter content. (paper)

  20. Health is a spiritual thing: perspectives of health care professionals and female Somali and Bangladeshi women on the health impacts of fasting during Ramadan.

    Science.gov (United States)

    Pathy, Rubini; Mills, Kelsey E; Gazeley, Sharon; Ridgley, Andrea; Kiran, Tara

    2011-02-01

    To explore perspectives of health care professionals and female Somali and Bangladeshi Muslim women on practices related to fasting during Ramadan, the impact of fasting on health and the role of health professionals during Ramadan. A cross-sectional qualitative study was conducted. Two culturally specific focus groups were conducted with six Somali and seven Bangladeshi Muslim women who observed Ramadan and lived in an inner-city neighbourhood of Toronto, Canada. Individual semi-structured interviews were conducted with 22 health care professionals practicing in this inner-city area (three of whom were Muslim). Data were analysed using thematic qualitative analysis. Both Muslim women and health care professionals recognised the spiritual significance of the Ramadan fast. Muslim participants considered the fast to be beneficial to health overall, whereas health care professionals tended to reflect on health concerns from fasting. Many health care professionals were not fully aware of fasting practices during Ramadan and some found it challenging to counsel patients about the health effects of fasting. Muslim women expressed disagreement regarding which medical interventions were permitted during fasting. They generally agreed that health care professionals should not specifically advise against fasting, but instead provide guidance on health maintenance while fasting. Both groups agreed that guidelines developed by the health care and faith communities together would be useful. There are a variety of health beliefs and observances among female Muslim Somali and Bangladeshi women and a range of knowledge, experience and opinions among health care professionals related to fasting during Ramadan and health. Overall, there is a need for improved communication between members of the Muslim community and health professionals in Canada about health issues related to fasting during Ramadan. Strategies could include published practice guidelines endorsed by the Muslim

  1. Uma história dos piratas: o princípio da construção do estereótipo do pirata caribenho que povoa o imaginário popular contemporâneo = A history of pirates: the principle of construction of stereotype pirate caribbean in the contemporary imaginary

    Directory of Open Access Journals (Sweden)

    Costa, Nicássio Martins da

    2014-01-01

    Full Text Available A construção do estereótipo do pirata caribenho se constrói com a ação de diversos veículos culturais de massa como cinema, literatura, séries televisivas, entre outros. Porém, é possível realizar um trabalho que identifique em que momento se deu o ponto de partida para que se realizassem essas construções. É neste objetivo que este artigo concentra seus esforços, voltando seu enfoque para uma obra oriunda do século XVIII. Tal obra possui um número interessante de peculiaridades que se estendem desde a identificação de seu verdadeiro autor, passam pelos diversos títulos atribuídos por cada editor e terminam nos objetivos pelos quais a mesma foi idealizada e na não concretização destes. Trata-se do livro A General HistoryofthePirates, que recebe em suas duas edições brasileiras os títulos de Uma História dos Piratas (2008 e Piratas: Uma História dos Roubos e Crimes de Piratas Famosos. Tais publicações dos mesmos textos divergem quanto a sua autoria, se escritos por Daniel Defoe ou pelo misterioso Capitão Charles Johnson do qual não se tem registros históricos. O caminho é analisado de forma breve, porém, procura exemplificar, com obras que partem do século XIX e se difundem popularizando o pirata como personagem de diversas produções contemporâneas

  2. Control of Influenza and Poliomyelitis with Killed Virus Vaccines

    Science.gov (United States)

    Salk, Jonas; Salk, Darrell

    1977-01-01

    Discusses control of poliomyelitis and influenza by live and killed virus vaccines. Considered are the etiological agents, pathogenic mechanisms and epidemiology of each disease. Reviews recent scientific studies of the diseases. Recommends use of killed virus vaccines in controlling both diseases. (CS)

  3. 9 CFR 113.210 - Feline Calicivirus Vaccine, Killed Virus.

    Science.gov (United States)

    2010-01-01

    ... Virus. 113.210 Section 113.210 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Killed Virus Vaccines § 113.210 Feline Calicivirus Vaccine, Killed Virus. Feline Calicivirus...

  4. 9 CFR 113.205 - Newcastle Disease Vaccine, Killed Virus.

    Science.gov (United States)

    2010-01-01

    ... Virus. 113.205 Section 113.205 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Killed Virus Vaccines § 113.205 Newcastle Disease Vaccine, Killed Virus. Newcastle Disease Vaccine...

  5. 9 CFR 113.211 - Feline Rhinotracheitis Vaccine, Killed Virus.

    Science.gov (United States)

    2010-01-01

    ... Virus. 113.211 Section 113.211 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Killed Virus Vaccines § 113.211 Feline Rhinotracheitis Vaccine, Killed Virus. Feline...

  6. 9 CFR 113.216 - Bovine Rhinotracheitis Vaccine, Killed Virus.

    Science.gov (United States)

    2010-01-01

    ... Virus. 113.216 Section 113.216 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Killed Virus Vaccines § 113.216 Bovine Rhinotracheitis Vaccine, Killed Virus. Infectious Bovine...

  7. 9 CFR 113.203 - Feline Panleukopenia Vaccine, Killed Virus.

    Science.gov (United States)

    2010-01-01

    ... Virus. 113.203 Section 113.203 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Killed Virus Vaccines § 113.203 Feline Panleukopenia Vaccine, Killed Virus. Feline Panleukopenia...

  8. Pseudomonas piscicida kills vibrios by two distinct mechanisms

    Science.gov (United States)

    Pseudoalteromonas piscicida is a naturally-occurring marine bacterium which kills competing bacteria, including vibrios. In studies by Richards et al. (AEM00175-17), three strains of P. piscicida were isolated and characterized. Strains secreted proteolytic enzymes which likely killed competing or...

  9. 9 CFR 113.214 - Parvovirus Vaccine, Killed Virus (Canine).

    Science.gov (United States)

    2010-01-01

    ... REQUIREMENTS Killed Virus Vaccines § 113.214 Parvovirus Vaccine, Killed Virus (Canine). Parvovirus Vaccine... antibody against canine parvovirus to determine susceptibility. A constant virus-varying serum... vaccinates and the controls shall be challenged with virulent canine parvovirus furnished or approved by...

  10. Killing Unwanted West Indies Mahogany Trees by Peeling and Frilling

    Science.gov (United States)

    R. W. Nobles; C. B. Briscoe

    1966-01-01

    Peeling and frilling each killed approximately 70 percent of treated West Indies mahogany, but peeling killed a higher percentage of trees between 18 and 33 centimeters (7 and 13 inches) than did frilling. Essentially all mortality occurred within the first 15 months following treatment.

  11. Northern and Southern Somali on the outskirts of Aarhus – a linguistic ethnographic analysis of language and belonging across time and space

    DEFF Research Database (Denmark)

    Daugaard, Line Møller

    -layered and ambivalent ways. The paper is based on a linguistic ethnographic study of language teaching across the curriculum in a Year 2 class in a public primary school in Denmark (Daugaard 2015). Using fieldwork as overarching research strategy, I followed obligatory teaching in Danish and English as well as ‘mother...... tongue teaching’ in Arabic, Dari, Pashto and Somali. The empirical material consists of fieldnotes, photographs, video and audio recordings and texts collected during participant observation in the language classroom, supplemented by interviews with children, mother tongue teachers and school management....

  12. Killing (absorption) versus survival in random motion

    Science.gov (United States)

    Garbaczewski, Piotr

    2017-09-01

    We address diffusion processes in a bounded domain, while focusing on somewhat unexplored affinities between the presence of absorbing and/or inaccessible boundaries. For the Brownian motion (Lévy-stable cases are briefly mentioned) model-independent features are established of the dynamical law that underlies the short-time behavior of these random paths, whose overall lifetime is predefined to be long. As a by-product, the limiting regime of a permanent trapping in a domain is obtained. We demonstrate that the adopted conditioning method, involving the so-called Bernstein transition function, works properly also in an unbounded domain, for stochastic processes with killing (Feynman-Kac kernels play the role of transition densities), provided the spectrum of the related semigroup operator is discrete. The method is shown to be useful in the case, when the spectrum of the generator goes down to zero and no isolated minimal (ground state) eigenvalue is in existence, like in the problem of the long-term survival on a half-line with a sink at origin.

  13. Novel innate cancer killing activity in humans

    Directory of Open Access Journals (Sweden)

    Lovato James

    2011-08-01

    Full Text Available Abstract Background In this study, we pilot tested an in vitro assay of cancer killing activity (CKA in circulating leukocytes of 22 cancer cases and 25 healthy controls. Methods Using a human cervical cancer cell line, HeLa, as target cells, we compared the CKA in circulating leukocytes, as effector cells, of cancer cases and controls. The CKA was normalized as percentages of total target cells during selected periods of incubation time and at selected effector/target cell ratios in comparison to no-effector-cell controls. Results Our results showed that CKA similar to that of our previous study of SR/CR mice was present in human circulating leukocytes but at profoundly different levels in individuals. Overall, males have a significantly higher CKA than females. The CKA levels in cancer cases were lower than that in healthy controls (mean ± SD: 36.97 ± 21.39 vs. 46.28 ± 27.22. Below-median CKA was significantly associated with case status (odds ratio = 4.36; 95% Confidence Interval = 1.06, 17.88 after adjustment of gender and race. Conclusions In freshly isolated human leukocytes, we were able to detect an apparent CKA in a similar manner to that of cancer-resistant SR/CR mice. The finding of CKA at lower levels in cancer patients suggests the possibility that it may be of a consequence of genetic, physiological, or pathological conditions, pending future studies with larger sample size.

  14. Combinatorial stresses kill pathogenic Candida species

    Science.gov (United States)

    Kaloriti, Despoina; Tillmann, Anna; Cook, Emily; Jacobsen, Mette; You, Tao; Lenardon, Megan; Ames, Lauren; Barahona, Mauricio; Chandrasekaran, Komelapriya; Coghill, George; Goodman, Daniel; Gow, Neil A. R.; Grebogi, Celso; Ho, Hsueh-Lui; Ingram, Piers; McDonagh, Andrew; De Moura, Alessandro P. S.; Pang, Wei; Puttnam, Melanie; Radmaneshfar, Elahe; Romano, Maria Carmen; Silk, Daniel; Stark, Jaroslav; Stumpf, Michael; Thiel, Marco; Thorne, Thomas; Usher, Jane; Yin, Zhikang; Haynes, Ken; Brown, Alistair J. P.

    2012-01-01

    Pathogenic microbes exist in dynamic niches and have evolved robust adaptive responses to promote survival in their hosts. The major fungal pathogens of humans, Candida albicans and Candida glabrata, are exposed to a range of environmental stresses in their hosts including osmotic, oxidative and nitrosative stresses. Significant efforts have been devoted to the characterization of the adaptive responses to each of these stresses. In the wild, cells are frequently exposed simultaneously to combinations of these stresses and yet the effects of such combinatorial stresses have not been explored. We have developed a common experimental platform to facilitate the comparison of combinatorial stress responses in C. glabrata and C. albicans. This platform is based on the growth of cells in buffered rich medium at 30°C, and was used to define relatively low, medium and high doses of osmotic (NaCl), oxidative (H 2O2) and nitrosative stresses (e.g., dipropylenetriamine (DPTA)-NONOate). The effects of combinatorial stresses were compared with the corresponding individual stresses under these growth conditions. We show for the first time that certain combinations of combinatorial stress are especially potent in terms of their ability to kill C. albicans and C. glabrata and/or inhibit their growth. This was the case for combinations of osmotic plus oxidative stress and for oxidative plus nitrosative stress. We predict that combinatorial stresses may be highly signif cant in host defences against these pathogenic yeasts. PMID:22463109

  15. Protection against hyperthermic cell killing by alanine

    International Nuclear Information System (INIS)

    Cunningham, A.; Henle, K.J.; Moss, A.J.; Nagle, W.A.

    1987-01-01

    Compounds capable of protecting cells against hyperthermia may provide new insights into potential mechanisms of thermotolerance and cellular heat death. The authors characterized heat protection by alanine and related compounds as a function of concentration, temperature and preincubation time. Alanine was added either to complete medium or to HBSS before hyperthermia. Maximal heat protection required 3 hr, 37 0 ; longer preincubation intervals resulted in lower levels of protection. Addition of alanine to medium after hyperthermia had no protective effect. Protection was concentration dependent with a 20- or 200-fold increase in cell survival after 40 min, 45 0 C at 60 mM in medium or in HBSS, respectively. Higher alanine concentrations up to 120mM did not significantly increase heat protection. A 45 0 -heat survival curve showed that 100mM alanine increased the D/sub q/ by approx. 12 min with little change in the D/sub o/. Hyperthermia of 1 hr at temperatures between 42 0 and 45 0 indicated that 100mM alanine shifted the isotoxic temperature by 0.5 Celsius degrees. Polymers of either L or D,L alanine and related compounds, like pyruvate, also protected cells against heat killing. These results indicate that heat protection by alanine shows characteristics that are not shared by polyhydroxy compounds

  16. Managing Threat, Cost, and Incentive to Kill: The Short- and Long-Term Effects of Intervention in Mass Killings

    Science.gov (United States)

    Kathman, Jacob D.; Wood, Reed M.

    2011-01-01

    How do third-party interventions affect the severity of mass killings? The authors theorize that episodes of mass killing are the consequence of two factors: (1) the threat perceptions of the perpetrators and (2) the cost of implementing genocidal policies relative to other alternatives. To reduce genocidal hostilities, interveners must address…

  17. Bacteriological quality of raw camel milk along the market value chain in Fafen zone, Ethiopian Somali regional state.

    Science.gov (United States)

    Abera, Tsegalem; Legesse, Yoseph; Mummed, Behar; Urga, Befekadu

    2016-05-26

    The camel is a multipurpose animal with a huge productive potential. Camel milk is a key food in arid and semi-arid areas of the African and Asian countries. The quality of milk is influenced by different bacteria present in milk. This study was conducted to evaluate total bacterial content in raw camel milk along the market chain in Fafen zone, Ethiopian Somali Regional State. One hundred twenty-six raw camel milk samples were collected from Gursum (47.1 %) and Babile (52.9 %) districts. The three sampling levels included were udder (14.7 %), milking bucket (29.4 %) and market (55.9 %). Milk samples were analyzed for total bacterial counts (TBC) and coliform counts (CC). Furthermore, major pathogens were isolated and identified. 108 (85.7 %) of raw camel milk samples demonstrated bacterial contamination. The overall mean TBC and CC of contaminated raw camel milk samples was 4.75 ± 0.17 and 4.03 ± 0.26 log CFU/ml, respectively. TBC increased from udder to market level and was higher in Gursum compared to Babile district (P < 0.05). Around 38.9 % of TBCs and 88.2 % CCs in contaminated raw camel milk samples were in the range considered unsafe for human utility. Staphylococcus spp. (89.8 %), Streptococcus spp. (53.7 %), E. coli (31.5 %), Salmonella spp. (17.6 %), Klebsiella spp. (5.6 %) and Enterobacter spp. (5.6 %) were the major bacterial microorganisms isolated. The majority of the bacterial isolates in this study showed high incidence in market as compared to production level. These results indicate a lack of compliance with good production practices and hygiene at milking, transportation and market of raw camel milk.

  18. Psychological traits underlying different killing methods among Malaysian male murderers.

    Science.gov (United States)

    Kamaluddin, Mohammad Rahim; Shariff, Nadiah Syariani; Nurfarliza, Siti; Othman, Azizah; Ismail, Khaidzir H; Mat Saat, Geshina Ayu

    2014-04-01

    Murder is the most notorious crime that violates religious, social and cultural norms. Examining the types and number of different killing methods that used are pivotal in a murder case. However, the psychological traits underlying specific and multiple killing methods are still understudied. The present study attempts to fill this gap in knowledge by identifying the underlying psychological traits of different killing methods among Malaysian murderers. The study adapted an observational cross-sectional methodology using a guided self-administered questionnaire for data collection. The sampling frame consisted of 71 Malaysian male murderers from 11 Malaysian prisons who were selected using purposive sampling method. The participants were also asked to provide the types and number of different killing methods used to kill their respective victims. An independent sample t-test was performed to establish the mean score difference of psychological traits between the murderers who used single and multiple types of killing methods. Kruskal-Wallis tests were carried out to ascertain the psychological trait differences between specific types of killing methods. The results suggest that specific psychological traits underlie the type and number of different killing methods used during murder. The majority (88.7%) of murderers used a single method of killing. Multiple methods of killing was evident in 'premeditated' murder compared to 'passion' murder, and revenge was a common motive. Examples of multiple methods are combinations of stabbing and strangulation or slashing and physical force. An exception was premeditated murder committed with shooting, when it was usually a single method, attributed to the high lethality of firearms. Shooting was also notable when the motive was financial gain or related to drug dealing. Murderers who used multiple killing methods were more aggressive and sadistic than those who used a single killing method. Those who used multiple methods or

  19. Killing a Peacock: A Case Study of the Targeted Killing of Admiral Isoroku Yamamoto

    Science.gov (United States)

    2015-03-24

    assertions by-in-large fell on deaf ears in the United States, Yamamoto nevertheless took special interest in Mitchell’s claims, and returned to Japan in...deliberations on April 17.106 Upon receiving an update brief of the planning order, Viccellio immediately identified a problem . He knew that the P-38’s fuel...what, it all happened all too fast to know and he was content on calling it a “team kill.”152 Instead, he left resolution of the issue to Barber and

  20. Kill a brand, keep a customer.

    Science.gov (United States)

    Kumar, Nirmalya

    2003-12-01

    Most brands don't make much money. Year after year, businesses generate 80% to 90% of their profits from less than 20% of their brands. Yet most companies tend to ignore loss-making brands, unaware of the hidden costs they incur. That's because executives believe it's easy to erase a brand; they have only to stop investing in it, they assume, and it will die a natural death. But they're wrong. When companies drop brands clumsily, they antagonize loyal customers: Research shows that seven times out of eight, when firms merge two brands, the market share of the new brand never reaches the combined share of the two original ones. It doesn't have to be that way. Smart companies use a four-step process to kill brands methodically. First, CEOs make the case for rationalization by getting groups of senior executives to conduct joint audits of the brand portfolio. These audits make the need to prune brands apparent throughout the organization. In the next stage, executives need to decide how many brands will be retained, which they do either by setting broad parameters that all brands must meet or by identifying the brands they need in order to cater to all the customer segments in their markets. Third, executives must dispose of the brands they've decided to drop, deciding in each case whether it is appropriate to merge, sell, milk, or just eliminate the brand outright. Finally, it's critical that executives invest the resources they've freed to grow the brands they've retained. Done right, dropping brands will result in a company poised for new growth from the source where it's likely to be found--its profitable brands.

  1. Did Vertigo Kill America's Forgotten Astronaut?

    Science.gov (United States)

    Bendrick, Gregg A.; Merlin, Peter W.

    2007-01-01

    On November 15, 1967, U.S. Air Force test pilot Major Michael J. Adams was killed while flying the X-15 rocket-propelled research vehicle in a parabolic spaceflight profile. This flight was part of a joint effort with NASA. An electrical short in one of the experiments aboard the vehicle caused electrical transients, resulting in excessive workload by the pilot. At altitude Major Adams inappropriately initiated a flat spin that led to a series of unusual aircraft attitudes upon atmospheric re-entry, ultimately causing structural failure of the airframe. Major Adams was known to experience vertigo (i.e. spatial disorientation) while flying the X-15, but all X-15 pilots most likely experienced vertigo (i.e. somatogravic, or "Pitch-Up", illusion) as a normal physiologic response to the accelerative forces involved. Major Adams probably experienced vertigo to a greater degree than did others, since prior aeromedical testing for astronaut selection at Brooks AFB revealed that he had an unusually high degree of labyrinthine sensitivity. Subsequent analysis reveals that after engine burnout, and through the zenith of the flight profile, he likely experienced the oculoagravic ("Elevator") illusion. Nonetheless, painstaking investigation after the mishap revealed that spatial disorientation (Type II, Recognized) was NOT the cause, but rather, a contributing factor. The cause was in fact the misinterpretation of a dual-use flight instrument (i.e. Loss of Mode Awareness), resulting in confusion between yaw and roll indications, with subsequent flight control input that was inappropriate. Because of the altitude achieved on this flight, Major Adams was awarded Astronaut wings posthumously. Understanding the potential for spatial disorientation, particularly the oculoagravic illusion, associated with parabolic spaceflight profiles, and understanding the importance of maintaining mode awareness in the context of automated cockpit design, are two lessons that have direct

  2. Generalized Killing-Yano equations in D=5 gauged supergravity

    International Nuclear Information System (INIS)

    Kubiznak, David; Kunduri, Hari K.; Yasui, Yukinori

    2009-01-01

    We propose a generalization of the (conformal) Killing-Yano equations relevant to D=5 minimal gauged supergravity. The generalization stems from the fact that the dual of the Maxwell flux, the 3-form *F, couples naturally to particles in the background as a 'torsion'. Killing-Yano tensors in the presence of torsion preserve most of the properties of the standard Killing-Yano tensors - exploited recently for the higher-dimensional rotating black holes of vacuum gravity with cosmological constant. In particular, the generalized closed conformal Killing-Yano 2-form gives rise to the tower of generalized closed conformal Killing-Yano tensors of increasing rank which in turn generate the tower of Killing tensors. An example of a generalized Killing-Yano tensor is found for the Chong-Cvetic-Lue-Pope black hole spacetime [Z.W. Chong, M. Cvetic, H. Lu, C.N. Pope, (hep-th/0506029)]. Such a tensor stands behind the separability of the Hamilton-Jacobi, Klein-Gordon, and Dirac equations in this background.

  3. Mapping of lithologic and structural units using multispectral imagery. [Afar-Triangle/Ethiopia and adjacent areas (Ethiopian Plateau, Somali Plateau, and parts of Yemen and Saudi Arabia)

    Science.gov (United States)

    Kronberg, P. (Principal Investigator)

    1974-01-01

    The author has identified the following significant results. ERTS-1 MSS imagery covering the Afar-Triangle/Ethiopia and adjacent regions (Ethiopian Plateau, Somali Plateau, and parts of Yemen and Saudi Arabi) was applied to the mapping of lithologic and structural units of the test area at a scale 1:1,000,000. Results of the geological evaluation of the ERTS-1 imagery of the Afar have proven the usefullness of this type of satellite data for regional geological mapping. Evaluation of the ERTS images also resulted in new aspects of the structural setting and tectonic development of the Afar-Triangle, where three large rift systems, the oceanic rifts of the Red Sea and Gulf of Aden and the continental East African rift system, seem to meet each other. Surface structures mapped by ERTS do not indicate that the oceanic rift of the Gulf of Aden (Sheba Ridge) continues into the area of continental crust west of the Gulf of Tadjura. ERTS data show that the Wonji fault belt of the African rift system does not enter or cut through the central Afar. The Aysha-Horst is not a Horst but an autochthonous spur of the Somali Plateau.

  4. Effect of feeding Neem (Azadirachta indica) and Acacia (Acacia senegal) tree foliage on nutritional and carcass parameters in short-eared Somali goats.

    Science.gov (United States)

    Hailemariam, Samson; Urge, Mengistu; Menkir, Sissay

    2016-02-01

    The study was conducted to determine the effects of dried foliage of Acacia senegal and Neem (Azadirachta indica) tree supplementations on feed intake, nutrient digestibility, growth, and carcass parameters in short-eared Somali goats. Twenty male intact short-eared Somali goat yearlings with an average live weight of 16.2 ± 1.08 (Mean ± SD) were assigned to four treatment groups, which comprised a basal diet of hay alone (T1) and supplementation with the tree foliages. Supplements consisted Neem tree (T2), A. senegal (T3) and the mixture of the two (1:1 ratio; T4) dried foliages. The crude protein (CP) content of Neem tree foliage, A. senegal, and their mixture were 16.92, 17.5 and 17.01 % of dry matter (DM), respectively. Total DM intake and digestibility of DM and organic matter were significantly (P senegal (67 %). The final body weights were higher (P Senegal. An average daily body weight (BW) gain was higher (P senegal (8.3 kg) among the supplemented groups, all of which are higher than the control (4.9 kg). It is concluded that the supplementation with tree foliage, especially with A. senegal tree foliage, on grass hay encouraged a better utilization of nutrients and animal performance as compared to goats fed on a basal diet of grass hay only.

  5. Detection of Rickettsia aeschlimannii and Rickettsia africae in ixodid ticks from Burkina Faso and Somali Region of Ethiopia by new real-time PCR assays.

    Science.gov (United States)

    Tomassone, L; De Meneghi, D; Adakal, H; Rodighiero, P; Pressi, G; Grego, E

    2016-10-01

    In the framework of cooperation for development projects in Burkina Faso and Ethiopia, we collected ixodid ticks from cattle, small ruminants and camels. We optimized new TaqMan Probe real-time PCR assays to detect Rickettsia aeschlimannii and Rickettsia africae OmpA gene in the collected samples. Rickettsia africae was identified in 75.0% Amblyomma variegatum (95%CI: 56.6-88.5), while R. aeschlimannii in 24.0% Hyalomma truncatum (95%CI: 9.4-45.1) and 50.0% H. rufipes (95%CI: 29.9-70.0) collected from cattle in different provinces throughout Burkina Faso. Ticks from the Libaan zone, Somali Region of Ethiopia, were also infected by R. africae (28.5% prevalence in Amblyomma gemma, 95%CI: 14.7-46.0) and R. aeschlimannii (27.0% H. truncatum, 95%CI: 5.0-62.9; 88.3% H. rufipes, 95%CI: 60.5-99.3). All tested ticks were adults. The developed diagnostic tools were highly sensitive and enabled us to rapidly classify R. aeschlimannii and R. africae, which were identified in Burkina Faso and in the Somali Region of Ethiopia for the first time. Further studies are needed to assess the zoonotic risk and prevalence of infection in local human populations, who have high contact rates with ticks and their animal hosts. Copyright © 2016 Elsevier GmbH. All rights reserved.

  6. Some spacetimes with higher rank Killing-Staeckel tensors

    International Nuclear Information System (INIS)

    Gibbons, G.W.; Houri, T.; Kubiznak, D.; Warnick, C.M.

    2011-01-01

    By applying the lightlike Eisenhart lift to several known examples of low-dimensional integrable systems admitting integrals of motion of higher-order in momenta, we obtain four- and higher-dimensional Lorentzian spacetimes with irreducible higher-rank Killing tensors. Such metrics, we believe, are first examples of spacetimes admitting higher-rank Killing tensors. Included in our examples is a four-dimensional supersymmetric pp-wave spacetime, whose geodesic flow is superintegrable. The Killing tensors satisfy a non-trivial Poisson-Schouten-Nijenhuis algebra. We discuss the extension to the quantum regime.

  7. HIV transcription is induced with some forms of cell killing

    International Nuclear Information System (INIS)

    Woloschak, G.E.; Schreck, S.; Chang-Liu, C.-M.; Libertin, C.R.

    1996-01-01

    Using HeLa cells stably transfected with an HIV-LTR-CAT construct', we demonstrated a peak in CAT induction that occurs in viable (but not necessarily cell-division-competent) cells 24 h following exposure to some cell-killing agents. Γ rays were the only cell-killing agent which did not induce HIV transcription; this can be attributed to the fact that γ-ray-induced apoptotic death requires function p53, which is missing in HeLa cells. For all other agents, HIV-LTR induction was dose-dependent and correlated with the amount of cell killing that occurred in the culture

  8. Factors Affecting Zebra Mussel Kill by the Bacterium Pseudomonas fluorescens

    Energy Technology Data Exchange (ETDEWEB)

    Daniel P. Molloy

    2004-02-24

    The specific purpose of this research project was to identify factors that affect zebra mussel kill by the bacterium Pseudomonas fluorescens. Test results obtained during this three-year project identified the following key variables as affecting mussel kill: treatment concentration, treatment duration, mussel siphoning activity, dissolved oxygen concentration, water temperature, and naturally suspended particle load. Using this latter information, the project culminated in a series of pipe tests which achieved high mussel kill inside power plants under once-through conditions using service water in artificial pipes.

  9. 40 CFR 180.1107 - Delta endotoxin of Bacillus thuringiensis variety kurstaki encapsulated into killed Pseudomonas...

    Science.gov (United States)

    2010-07-01

    ... thuringiensis variety kurstaki encapsulated into killed Pseudomonas fluorescens; exemption from the requirement... killed Pseudomonas fluorescens; exemption from the requirement of a tolerance. The delta endotoxin of Bacillus thuringiensis variety kurstaki encapsulated into killed Pseudomonas fluorescens is exempt from the...

  10. Selective Killing of Prostate Tumor Cells by Cytocidal Viruses

    National Research Council Canada - National Science Library

    Lyles, Douglas

    2003-01-01

    .... The novelty in our approach is our ability to enhance the selectivity of killing of tumor cells versus normal cells by manipulating the viral genes that control the antiviral interferon response...

  11. Selective Killing of Prostate Tumor Cells by Cytocidal Viruses

    National Research Council Canada - National Science Library

    Lyles, Douglas

    2004-01-01

    .... The novelty in our approach is our ability to enhance the selectivity of killing of tumor cells versus normal cells by manipulating the viral genes that control the antiviral interferon response...

  12. On Discrete Killing Vector Fields and Patterns on Surfaces

    KAUST Repository

    Ben-Chen, Mirela; Butscher, Adrian; Solomon, Justin; Guibas, Leonidas

    2010-01-01

    , and show how to discretize these concepts for generating such vector fields on a triangulated mesh. We discuss the properties of approximate Killing Vector Fields, and propose an application to utilize them for texture and geometry synthesis. Journal

  13. Selective Killing of Prostate Tumor Cells by Cytocidal Viruses

    National Research Council Canada - National Science Library

    Lyles, Douglas S

    2005-01-01

    ...). The novelty in our approach is our ability to enhance the selectivity of VSV-induced killing of tumor cells versus normal cells by manipulating the viral genes that control the antiviral interferon response...

  14. Thou Shalt Not Kill: Conscientious Objection and the Decalogue

    Science.gov (United States)

    2012-04-01

    used to condone animal cruelty .66 Second, n¥1 (ratsach) is not used in the context of proper punishment for a crime.67 Alan Cole explains...used to refer to the killing animals for food and sacrifices.63 Scripture records that God allowed the killing of animals for food.64 God also allowed...the slaying of animals for sacrifices.65 Consequently, the sixth commandment cannot be used to support the practice of vegetarianism nor can it be

  15. Vertebrate road kill survey on a highway in southern Brazil

    Directory of Open Access Journals (Sweden)

    Luiz Liberato Costa Corrêa

    2017-06-01

    Full Text Available Highways are a major factor acting in the decline of several wildlife populations. Impact occurs due to the continuous flow of motor vehicles over tracks and collision with animals using the same area. This study aimed to list road killed wild vertebrates found in highways in the Pampa Biome, state of Rio Grande do Sul, over an entire year. The taxa found (amphibians, reptiles, birds and mammals were identified to species level and their frequency of occurrence was seasonally registered. Along 2,160 km, we found 318 road killed individuals, totaling 65 species. This number represents an average of 0.147 road killed specimens by kilometer (that is, 1 individual each 7 km. Of these, seven species are under threat of extinction in the state of Rio Grande do Sul. We also found a seasonal pattern among road kills, in which the highest number of road killed animals was registered in the summer and spring months. These results contribute to increase knowledge about which species are most impacted by road kill on highways of the Pampa Biome. Such data can be used as an indicator for the implementation of measures by competent bodies to mitigate impacts of highways in the state of Rio Grande do Sul.

  16. Role of nitric oxide and superoxide in Giardia lamblia killing

    Directory of Open Access Journals (Sweden)

    P.D. Fernandes

    1997-01-01

    Full Text Available Giardia lamblia trophozoites were incubated for 2 h with activated murine macrophages, nitric oxide (NO donors or a superoxide anion generator (20 mU/ml xanthine oxidase plus 1 mM xanthine. Activated macrophages were cytotoxic to Giardia trophozoites (~60% dead trophozoites. This effect was inhibited (>90% by an NO synthase inhibitor (200 µM and unaffected by superoxide dismutase (SOD, 300 U/ml. Giardia trophozoites were killed by the NO donors, S-nitroso-acetyl-penicillamine (SNAP and sodium nitroprusside (SNP in a dose-dependent manner (LD50 300 and 50 µM, respectively. A dual NO-superoxide anion donor, 3-morpholino-sydnonimine hydrochloride (SIN-1, did not have a killing effect in concentrations up to 1 mM. However, when SOD (300 U/ml was added simultaneously with SIN-1 to Giardia, a significant trophozoite-killing effect was observed (~35% dead trophozoites at 1 mM. The mixture of SNAP or SNP with superoxide anion, which yields peroxynitrite, abolished the trophozoite killing induced by NO donors. Authentic peroxynitrite only killed trophozoites at very high concentrations (3 mM. These results indicate that NO accounts for Giardia trophozoite killing and this effect is not mediated by peroxynitrite

  17. Husbandry, breeding practices, and production constraints of camel in the pastoral communities of Afar and Somali, Ethiopia

    Directory of Open Access Journals (Sweden)

    Yosef Tadesse

    2014-12-01

    Full Text Available The objectives of this paper were to identify and describe husbandry practices, herd structure, owners’ trait preferences, breeding practices, and production constraints of camel in the two major camel rearing pastoral communities, viz. Afar and Somali, to generate baseline information that would help to plan possible breed improvement strategies and options for the different camel populations. The study sites were selected purposively while households from each of the sites randomly. Data were collected using formal questionnaires and focus group discussion. Results showed that average camel population per household was higher in Mille (28.06±2.27, Gode (27.51±2.02, and Moyale (24.07±2.13 districts. Female camel populations with age of >1 year contributes 78-83% of the total camel herd population in all the study districts. Higher number of female animals in the herd in the arid environment means providing continuous supply of milk and allows a rapid recovery of herd numbers after a disease outbreak or drought occurrence. This shows that pastoralists breeding objectives are in relation to the arid environment and female population in the herd. Most of the pastoral communities utilize a single breeding male camel per 40-50 female camels and this will affect productivity and heterogeneity of camel population. With regard to trait preference, all pastoral communities ranked milk yield as the first trait of choice, except Liben district in which adaptation trait was the primary preference. Growth trait ranked second in Mille, Gode, Liben, and Jijiga pastoral communities where as adaptation trait ranked second in Amibara and Shinille pastoral communities. The major camel production constraints were feed, diseases, and lack of water in that order and the major cause of the constraints was the recurrent drought occurred during the past 2-3 decades in the two regions. Therefore, in planning and implementation of the breeding strategies for small

  18. Armed conflicts have an impact on the spread of tuberculosis: the case of the Somali Regional State of Ethiopia

    Directory of Open Access Journals (Sweden)

    Gele Abdi A

    2010-01-01

    Full Text Available Abstract A pessimistic view of the impact of armed conflicts on the control of infectious diseases has generated great interest in the role of conflicts on the global TB epidemic. Nowhere in the world is such interest more palpable than in the Horn of Africa Region, comprising Ethiopia, Somalia, Eritrea, Djibouti, Kenya and Sudan. An expanding literature has demonstrated that armed conflicts stall disease control programs through distraction of health system, interruption of patients' ability to seek health care, and the diversion of economic resources to military ends rather than health needs. Nonetheless, until very recently, no research has been done to address the impact of armed conflict on TB epidemics in the Somali Regional State (SRS of Ethiopia. Methods This study is based on the cross-sectional data collected in 2007, utilizing structured questionnaires filled-out by a sample of 226 TB patients in the SRS of Ethiopia. Data was obtained on the delay patients experienced in receiving a diagnosis of TB, on the biomedical knowledge of TB that patients had, and the level of self-treatment by patients. The outcome variables in this study are the delay in the diagnosis of TB experienced by patients, and extent of self-treatment utilized by patients. Our main explanatory variable was place of residence, which was dichotomized as being in 'conflict zones' and in 'non-conflict zones'. Demographic data was collected for statistical control. Chi-square and Mann-Whitney tests were used on calculations of group differences. Logistic regression analysis was used to determine the association between outcome and predictor variables. Results Two hundred and twenty six TB patients were interviewed. The median delay in the diagnosis of TB was 120 days and 60 days for patients from conflict zones and from non-conflict zones, respectively. Moreover, 74% of the patients residing in conflict zones undertook self-treatment prior to their diagnosis. The

  19. Understanding the unique experiences, perspectives and sexual and reproductive health needs of very young adolescents: Somali refugees in Ethiopia.

    Science.gov (United States)

    Ortiz-Echevarria, Luis; Greeley, Meghan; Bawoke, Tenaw; Zimmerman, Linnea; Robinson, Courtland; Schlecht, Jennifer

    2017-01-01

    Kobe Refugee camp hosts roughly 39,000 refugees displaced from Somalia during the 2011-2012 Horn of Africa Crisis. Sexual and reproductive health, as with the greater issues of health and well-being for adolescents displaced from this crisis remain largely unknown and neglected. In 2013, the Women's Refugee Commission, Johns Hopkins University, and International Medical Corps in Ethiopia, implemented qualitative and quantitative research to explore the factors and risks that impact the health of very young adolescents (VYAs), those 10-14 years of age, in this setting. This paper presents findings from the qualitative effort. Focus group discussions (FGD), incorporating community mapping and photo elicitation activities, were conducted with 10-12 and 13-14 year-olds to obtain information about their own perspectives, experiences and values. FGDs were also implemented with 15-16 year-olds and adults, to consider their perspectives on the sexual and reproductive health needs and risks of VYAs. This research identified several factors that were found to influence the health and well-being of VYAs in Kobe refugee camp, including newfound access to education and security, combined with gender divisions and parental communication around early SRH and puberty that remained intact from traditional Somali culture. Girls were found to face an additional risk of child marriage and early pregnancy exacerbated since displacement, which significantly limited their ability to access education and achieve future aspirations. Findings from this study could help to inform future programs in Kobe and similar contexts involving long-term displacement from conflict, focusing on the health and development needs of VYAs. Future programs should consider the determinants of positive VYA health and development, including access to education, gender equity, and safety.By better understanding the unique experiences, perspectives and needs of VYAs, practitioners, policy makers and donors can

  20. Karr’s Kill Cult: Virtual Cults and Pseudo-Killing in the Digital Age

    Directory of Open Access Journals (Sweden)

    Jeremy Biles

    2012-03-01

    Full Text Available Most readers will recall the 1996 tragedy in which six-year-old beauty-pageant princess JonBenét Ramsey was found bound, gagged, and strangled in the basement of her parents’ home, inciting an orgy of media coverage. What readers may not know is that John Mark Karr—the imminently creepy individual who falsely confessed to the killing, and whose sordid past includes an arrest for possession of child pornography—has continued to make news as an alleged cyberstalker and would-be cult leader. This article claims that whereas a real serial killer is compelled to murder again and again with different victims, Karr is compelled to repeat the singular murder of JonBenét Ramsey the only way he can—in a virtual reality constituted by writing.

  1. Neutrophils kill the parasite Trichomonas vaginalis using trogocytosis

    Science.gov (United States)

    Mercer, Frances; Ng, Shek Hang; Brown, Taylor M.; Boatman, Grace; Johnson, Patricia J.

    2018-01-01

    T. vaginalis, a human-infective parasite, causes the most common nonviral sexually transmitted infection (STI) worldwide and contributes to adverse inflammatory disorders. The immune response to T. vaginalis is poorly understood. Neutrophils (polymorphonuclear cells [PMNs]) are the major immune cell present at the T. vaginalis–host interface and are thought to clear T. vaginalis. However, the mechanism of PMN clearance of T. vaginalis has not been characterized. We demonstrate that human PMNs rapidly kill T. vaginalis in a dose-dependent, contact-dependent, and neutrophil extracellular trap (NET)-independent manner. In contrast to phagocytosis, we observed that PMN killing of T. vaginalis involves taking “bites” of T. vaginalis prior to parasite death, using trogocytosis to achieve pathogen killing. Both trogocytosis and parasite killing are dependent on the presence of PMN serine proteases and human serum factors. Our analyses provide the first demonstration, to our knowledge, of a mammalian phagocyte using trogocytosis for pathogen clearance and reveal a novel mechanism used by PMNs to kill a large, highly motile target. PMID:29408891

  2. Structural equations for Killing tensors of order two. II

    International Nuclear Information System (INIS)

    Hauser, I.; Malhiot, R.J.

    1975-01-01

    In a preceding paper, a new form of the structural equations for any Killing tensor of order two have been derived; these equations constitute a system analogous to the Killing vector equations Nabla/sub alpha/ K/sub beta/ = ω/sub alpha beta/ = -ω/sub beta alpha/ and Nabla/sub gamma/ ω/sub alpha beta = R/sub alpha beta gamma delta/ K/sup delta/. The first integrability condition for the Killing tensor structural equations is now derived. The structural equations and the integrability condition have forms which can readily be expressed in terms of a null tetrad to furnish a Killing tensor parallel of the Newman--Penrose equations; this is briefly described. The integrability condition implies the new result, for any given space--time, that the dimension of the set of second-order Killing tensors attains its maximum possible value of 50 only if the space--time is of constant curvature. Potential applications of the structural equations are discussed

  3. Prairie dogs increase fitness by killing interspecific competitors.

    Science.gov (United States)

    Hoogland, John L; Brown, Charles R

    2016-03-30

    Interspecific competition commonly selects for divergence in ecology, morphology or physiology, but direct observation of interspecific competition under natural conditions is difficult. Herbivorous white-tailed prairie dogs (Cynomys leucurus) employ an unusual strategy to reduce interspecific competition: they kill, but do not consume, herbivorous Wyoming ground squirrels (Urocitellus elegans) encountered in the prairie dog territories. Results from a 6-year study in Colorado, USA, revealed that interspecific killing of ground squirrels by prairie dogs was common, involving 47 different killers; 19 prairie dogs were serial killers in the same or consecutive years, and 30% of female prairie dogs killed at least one ground squirrel over their lifetimes. Females that killed ground squirrels had significantly higher annual and lifetime fitness than non-killers, probably because of decreased interspecific competition for vegetation. Our results document the first case of interspecific killing of competing individuals unrelated to predation (IK) among herbivorous mammals in the wild, and show that IK enhances fitness for animals living under natural conditions. © 2016 The Author(s).

  4. Comparison of manual and automated AmpliSeq™ workflows in the typing of a Somali population with the Precision ID Identity Panel

    DEFF Research Database (Denmark)

    van der Heijden, Suzanne; de Oliveira, Susanne Juel; Kampmann, Marie-Louise

    2017-01-01

    to compare different AmpliSeq™ workflows to investigate the possibility of using automated library building in forensic genetic case work. In order to do so, the SNP typing of the Somalis was performed using three different workflows: 1) manual library building and sequencing on the Ion PGM™, 2) automated...... workflows. The Biomek(®)3000/Ion PGM™ workflow was found to perform similarly to the manual/Ion PGM™ workflow. This argues for the use of automated library building in forensic genetic case work. Automated library building decreases the workload of the laboratory staff, decreases the risk of pipetting...... library building using the Biomek(®)3000 and sequencing on the Ion PGM™, and 3) automated library building using the Ion Chef™ and sequencing on the Ion S5™. AmpliSeq™ workflows were compared based on coverage, locus balance, noise, and heterozygote balance. Overall, the Ion Chef™/Ion S5™ workflow...

  5. 77 FR 10960 - Security Zone, East River and Bronx Kill; Randalls and Wards Islands, NY

    Science.gov (United States)

    2012-02-24

    ...'' W (Port Morris Stacks), and all waters of the Bronx Kill southeast of the Bronx Kill Rail Road...-AA87 Security Zone, East River and Bronx Kill; Randalls and Wards Islands, NY AGENCY: Coast Guard, DHS... waters of the East River and Bronx Kill, in the vicinity of Randalls and Wards Islands, New York. This...

  6. Is female circumcision evolving or dissolving in Norway? A qualitative study on attitudes toward the practice among young Somalis in the Oslo area.

    Science.gov (United States)

    Gele, Abdi A; Sagbakken, Mette; Kumar, Bernadette

    2015-01-01

    Female genital mutilation or female circumcision (FC) is increasingly visible on the global health and development agenda - both as a matter of social justice and equality for women and as a research priority. Norway is one of the global nations hosting a large number of immigrants from FC-practicing countries, the majority from Somalia. To help counteract this practice, Norway has adopted a multifaceted policy approach that employs one of the toughest measures against FC in the world. However, little is known about the impact of Norway's approach on the attitudes toward the practice among traditional FC-practicing communities in Norway. Against this background, this qualitative study explores the attitudes toward FC among young Somalis between the ages of 16 to 22 living in the Oslo and Akershus regions of Norway. Findings indicate that young Somalis in the Oslo area have, to a large extent, changed their attitude toward the practice. This was shown by the participants' support and sympathy toward criminalization of FC in Norway, which they believed was an important step toward saving young girls from the harmful consequences of FC. Most of the uncircumcised girls see their uncircumcised status as being normal, whereas they see circumcised girls as survivors of violence and injustice. Moreover, the fact that male participants prefer a marriage to uncircumcised girls is a strong condition for change, since if uncut girls are seen as marriageable then parents are unlikely to want to circumcise them. As newly arrived immigrants continue to have positive attitudes toward the practice, knowledge of FC should be integrated into introduction program classes that immigrants attend shortly after their residence permit is granted. This study adds to the knowledge of the process of the abandonment of FC among immigrants in Western countries.

  7. Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells

    Science.gov (United States)

    Song, Chang W.; Lee, Hyemi; Dings, Ruud P. M.; Williams, Brent; Powers, John; Santos, Troy Dos; Choi, Bo-Hwa; Park, Heon Joo

    2012-01-01

    The anti-cancer effects of metformin, the most widely used drug for type 2 diabetes, alone or in combination with ionizing radiation were studied with MCF-7 human breast cancer cells and FSaII mouse fibrosarcoma cells. Clinically achievable concentrations of metformin caused significant clonogenic death in cancer cells. Importantly, metformin was preferentially cytotoxic to cancer stem cells relative to non-cancer stem cells. Metformin increased the radiosensitivity of cancer cells in vitro, and significantly enhanced the radiation-induced growth delay of FSaII tumors (s.c.) in the legs of C3H mice. Both metformin and ionizing radiation activated AMPK leading to inactivation of mTOR and suppression of its downstream effectors such as S6K1 and 4EBP1, a crucial signaling pathway for proliferation and survival of cancer cells, in vitro as well as in the in vivo tumors. Conclusion: Metformin kills and radiosensitizes cancer cells and eradicates radioresistant cancer stem cells by activating AMPK and suppressing mTOR. PMID:22500211

  8. Inflatable kill packers used in working over Kuwaiti wells

    Energy Technology Data Exchange (ETDEWEB)

    Miller, D. (Baker Oil Tools, Houston, TX (US)); Conover, G. (Baker Service Tools, Houston, TX (US))

    1992-03-09

    This paper reports on inflatable packers which are being used with great success in post-well capping workover operations in Kuwait oil fields. In mid-January, about one kill packer was being run per day. Use is expected to increase in March when a second post-capping crew arrives. Of several thousand unconventional ideas submitted to Kuwait Oil Co. (KOC) for controlling the well fires left in the aftermath of lst year's Gulf War, only about a dozen were actually used. Inflatable kill packers, designed and manufactured by Baker Service Tools and marketed by Baker Oil Tools, were one of the ideas that proved effective. The kill packers are modifications of Baker's inflatable packers that have successfully been used in capping producers on many blowouts throughout the world, including the Piper Alpha disaster in the North Sea and the Saga blowout offshore Norway.

  9. γ-rays kill grasshopper primary spermatocytes in groups

    International Nuclear Information System (INIS)

    Al-Taweel, A.A.; Shawkit, M.A.; Fox, D.P.

    1985-01-01

    Primary spermatocyte killing by γ-rays was studied in the grasshopper Heteracris littoralis in which spermatogenic development occurs in cysts containing a maximum of 64 cells during the first meiotic division. Cell killing at this stage is not random and mainly involves the death of whole cysts. The dose-response curve for cell killing has complex kinetics with at least two components but lacks any shoulder at low doses, thus indicating no repair of the lethal damage. Cell loss is apparent from surviving cysts as early as 45 min post irradiation but loss of > 24 cells is incompatible with cyst survival. Loss of fewer than 24 cells also is not random since certain values for cell loss are frequently observed while other, interspersed values are not seen at all. (Auth.)

  10. Supersymmetric backgrounds, the Killing superalgebra, and generalised special holonomy

    Energy Technology Data Exchange (ETDEWEB)

    Coimbra, André [Institut des Hautes Études Scientifiques, Le Bois-Marie,35 route de Chartres, F-91440 Bures-sur-Yvette (France); Strickland-Constable, Charles [Institut des Hautes Études Scientifiques, Le Bois-Marie,35 route de Chartres, F-91440 Bures-sur-Yvette (France); Institut de physique théorique, Université Paris Saclay, CEA, CNRS,Orme des Merisiers, F-91191 Gif-sur-Yvette (France)

    2016-11-10

    We prove that, for M theory or type II, generic Minkowski flux backgrounds preserving N supersymmetries in dimensions D≥4 correspond precisely to integrable generalised G{sub N} structures, where G{sub N} is the generalised structure group defined by the Killing spinors. In other words, they are the analogues of special holonomy manifolds in E{sub d(d)}×ℝ{sup +} generalised geometry. In establishing this result, we introduce the Kosmann-Dorfman bracket, a generalisation of Kosmann’s Lie derivative of spinors. This allows us to write down the internal sector of the Killing superalgebra, which takes a rather simple form and whose closure is the key step in proving the main result. In addition, we find that the eleven-dimensional Killing superalgebra of these backgrounds is necessarily the supertranslational part of the N-extended super-Poincaré algebra.

  11. On Discrete Killing Vector Fields and Patterns on Surfaces

    KAUST Repository

    Ben-Chen, Mirela

    2010-09-21

    Symmetry is one of the most important properties of a shape, unifying form and function. It encodes semantic information on one hand, and affects the shape\\'s aesthetic value on the other. Symmetry comes in many flavors, amongst the most interesting being intrinsic symmetry, which is defined only in terms of the intrinsic geometry of the shape. Continuous intrinsic symmetries can be represented using infinitesimal rigid transformations, which are given as tangent vector fields on the surface - known as Killing Vector Fields. As exact symmetries are quite rare, especially when considering noisy sampled surfaces, we propose a method for relaxing the exact symmetry constraint to allow for approximate symmetries and approximate Killing Vector Fields, and show how to discretize these concepts for generating such vector fields on a triangulated mesh. We discuss the properties of approximate Killing Vector Fields, and propose an application to utilize them for texture and geometry synthesis. Journal compilation © 2010 The Eurographics Association and Blackwell Publishing Ltd.

  12. Along-dip variations of structural style in the Somali Basin deep-water fold and thrust belt (East Africa)

    Science.gov (United States)

    Cruciani, Francesco; Rinaldo Barchi, Massimiliano

    2014-05-01

    Continental passive margins are place of extended slope-failure phenomena, which can lead to the formation of gravity-driven deep-water fold and thrust belts (DW-FTBs), in regions where no far-field compressional stress is active. These giant geological features, which are confined to the sedimentary section, consist of extensional-compressional linked systems detached over a common décollement, generally salt or shales. The continental passive margin of northern Kenya and southern Somalia is an excellent and relatively unexplored site for recognizing and understanding the DW-FTBs originated over a regional shale décollement. In this study we have interpreted a 2D seismic data-set of the 1980s, hosted by Marine Geoscience Data System at Lamont-Doherty Earth Observatory of Columbia University (http://www.marine-geo.org), and recently reprocessed by ENI, in order to investigate the structural style of a DW-FTB developed offshore of northern Kenya and southern Somalia (Somali Basin). This region records the oldest sedimentary section of the Indian Ocean since the breakup of Gondwana began in the Middle-Lower Jurassic separating Madagascar from Africa. From the Upper Cretaceous to at least the Lower Miocene, the margin has been characterized by gravitational collapse leading to the formation of a DW-FTB extending more than 400 km along-strike. The northern portion of the DW-FTB is about 150 km wide, whilst in the southern portion is few tens of km wide. We analysed the northern portion along a regional seismic section. Our study represents the first detailed structural interpretation of this DW-FTB since its discovery in the 1980s. The good quality of the available reprocessed seismic data has allowed us to identify remarkable along-dip variations in the structural style. The basal detachment constantly deepens landward, in agreement with a prevailing gravity-spreading deformation process (as in the case of the Niger Delta). On the seismic data are not visible, as

  13. Role of copper oxides in contact killing of bacteria.

    Science.gov (United States)

    Hans, Michael; Erbe, Andreas; Mathews, Salima; Chen, Ying; Solioz, Marc; Mücklich, Frank

    2013-12-31

    The potential of metallic copper as an intrinsically antibacterial material is gaining increasing attention in the face of growing antibiotics resistance of bacteria. However, the mechanism of the so-called "contact killing" of bacteria by copper surfaces is poorly understood and requires further investigation. In particular, the influences of bacteria-metal interaction, media composition, and copper surface chemistry on contact killing are not fully understood. In this study, copper oxide formation on copper during standard antimicrobial testing was measured in situ by spectroscopic ellipsometry. In parallel, contact killing under these conditions was assessed with bacteria in phosphate buffered saline (PBS) or Tris-Cl. For comparison, defined Cu2O and CuO layers were thermally generated and characterized by grazing incidence X-ray diffraction. The antibacterial properties of these copper oxides were tested under the conditions used above. Finally, copper ion release was recorded for both buffer systems by inductively coupled plasma atomic absorption spectroscopy, and exposed copper samples were analyzed for topographical surface alterations. It was found that there was a fairly even growth of CuO under wet plating conditions, reaching 4-10 nm in 300 min, but no measurable Cu2O was formed during this time. CuO was found to significantly inhibit contact killing, compared to pure copper. In contrast, thermally generated Cu2O was essentially as effective in contact killing as pure copper. Copper ion release from the different surfaces roughly correlated with their antibacterial efficacy and was highest for pure copper, followed by Cu2O and CuO. Tris-Cl induced a 10-50-fold faster copper ion release compared to PBS. Since the Cu2O that primarily forms on copper under ambient conditions is as active in contact killing as pure copper, antimicrobial objects will retain their antimicrobial properties even after oxide formation.

  14. Single-hit mechanism of tumour cell killing by radiation.

    Science.gov (United States)

    Chapman, J D

    2003-02-01

    To review the relative importance of the single-hit mechanism of radiation killing for tumour response to 1.8-2.0 Gy day(-1) fractions and to low dose-rate brachytherapy. Tumour cell killing by ionizing radiation is well described by the linear-quadratic equation that contains two independent components distinguished by dose kinetics. Analyses of tumour cell survival curves that contain six or more dose points usually provide good estimates of the alpha- and beta-inactivation coefficients. Superior estimates of tumour cell intrinsic radiosensitivity are obtained when synchronized populations are employed. The characteristics of single-hit inactivation of tumour cells are reviewed and compared with the characteristics of beta-inactivation. Potential molecular targets associated with single-hit inactivation are discussed along with strategies for potentiating cell killing by this mechanism. The single-hit mechanism of tumour cell killing shows no dependence on dose-rate and, consequently, no evidence of sublethal damage repair. It is uniquely potentiated by high linear-energy-transfer radiation, exhibits a smaller oxygen enhancement ratio and exhibits a larger indirect effect by hydroxyl radicals than the beta-mechanism. alpha-inactivation coefficients vary slightly throughout interphase but mitotic cells exhibit extremely high alpha-coefficients in the range of those observed for lymphocytes and some repair-deficient cells. Evidence is accumulating to suggest that chromatin in compacted form could be a radiation-hypersensitive target associated with single-hit radiation killing. Analyses of tumour cell survival curves demonstrate that it is the single-hit mechanism (alpha) that determines the majority of cell killing after doses of 2Gy and that this mechanism is highly variable between tumour cell lines. The characteristics of single-hit inactivation are qualitatively and quantitatively distinct from those of beta-inactivation. Compacted chromatin in tumour cells

  15. It?s Not Just Conflict That Motivates Killing of Orangutans

    OpenAIRE

    Davis, Jacqueline T.; Mengersen, Kerrie; Abram, Nicola K.; Ancrenaz, Marc; Wells, Jessie A.; Meijaard, Erik

    2013-01-01

    We investigated why orangutans are being killed in Kalimantan, Indonesia, and the role of conflict in these killings. Based on an analysis of interview data from over 5,000 respondents in over 450 villages, we also assessed the socio-ecological factors associated with conflict and non-conflict killings. Most respondents never kill orangutans. Those who reported having personally killed an orangutan primarily did so for non-conflict reasons; for example, 56% of these respondents said that the ...

  16. Traffics and wildlife: A preliminary study on road-kill

    OpenAIRE

    Rustiati, Elly Lestari

    2012-01-01

    This paper presents the preliminary finding on road kill survey by direct observations onthe high ways. The road-kills recorded of small wildlife, including medium size-mammal (2.50%, n =1), birds (5.00%, n = 2) and small mammals (92.50%, n = 37). The small mammals include the mostcommon mammals in the areas, squirrels, raccoons, skunks and woodchuck. Of mammals, squirrels(35.00%) were the highest recorded, followed by woodchucks (25.00%), mice/shrew (17.50%),raccoons (10.00%), skunk (5.00%) ...

  17. Perturbative stability of the approximate Killing field eigenvalue problem

    International Nuclear Information System (INIS)

    Beetle, Christopher; Wilder, Shawn

    2014-01-01

    An approximate Killing field may be defined on a compact, Riemannian geometry by solving an eigenvalue problem for a certain elliptic operator. This paper studies the effect of small perturbations in the Riemannian metric on the resulting vector field. It shows that small metric perturbations, as measured using a Sobolev-type supremum norm on the space of Riemannian geometries on a fixed manifold, yield small perturbations in the approximate Killing field, as measured using a Hilbert-type square integral norm. It also discusses applications to the problem of computing the spin of a generic black hole in general relativity. (paper)

  18. A radiolabel release microassay for phagocytic killing of Candida albicans

    International Nuclear Information System (INIS)

    Bistoni, F.; Baccarini, M.; Blasi, E.; Marconi, P.; Puccetti, P.

    1982-01-01

    The chromium-51 release technique for quantifying intracellular killing of radiolabelled Candida albicans particles was exploited in a microassay in which murine and human phagocytes acted as effectors under peculiarly simple conditions. At appropriate effector: target ratios and with a 4 h incubation, up to 50% specific chromium release could be detected in the supernatant with no need for opsonization or lysis of phagocytes. This simple microassay permits easy-to-perform, simultaneous testing of a variety of different phagocytes even if only available in limited amounts, and provides an objective measurement of intracellular killing of Candida albicans. (Auth.)

  19. Keberanian Dalam Novel to Kill a Mockingbird Karya Harper Lee

    OpenAIRE

    Tiolemba, Melissa

    2013-01-01

    The skripsi is entitled “Keberanian dalam Novel To Kill a Mockingbird by Harper Lee”. The objective of this research is to analyze the bravery as the main theme in the novel To Kill a Mockingbird. The data are collected by focusing on the character, plot and setting which describe about the main theme in the story. This research uses the theory of Stanton (1965) in analyzing the data. The writer uses descriptive method intrinsically. Intrinsic approach is to examine the elements within the no...

  20. Estimation in Discretely Observed Diffusions Killed at a Threshold

    DEFF Research Database (Denmark)

    Bibbona, Enrico; Ditlevsen, Susanne

    2013-01-01

    are modelled as discretely observed diffusions which are killed when the threshold is reached. Statistical inference is often based on a misspecified likelihood ignoring the presence of the threshold causing severe bias, e.g. the bias incurred in the drift parameters of the Ornstein–Uhlenbeck model...... for biological relevant parameters can be up to 25–100 per cent. We compute or approximate the likelihood function of the killed process. When estimating from a single trajectory, considerable bias may still be present, and the distribution of the estimates can be heavily skewed and with a huge variance...

  1. Cars kill chimpanzees: case report of a wild chimpanzee killed on a road at Bulindi, Uganda.

    Science.gov (United States)

    McLennan, Matthew R; Asiimwe, Caroline

    2016-07-01

    Roads have broadly adverse impacts on wildlife, including nonhuman primates. One direct effect is mortality from collisions with vehicles. While highly undesirable, roadkills provide valuable information on the health and condition of endangered species. We present a case report of a wild chimpanzee (Pan troglodytes schweinfurthii) killed crossing a road in Bulindi, Uganda, where chimpanzees inhabit forest fragments amid farmland. Details of the collision are constructed from eyewitness accounts of pedestrians. Physical examination of the cadaver indicated good overall body condition; at 40 kg, the deceased female was heavier than usual for an adult female East African chimpanzee. No external wounds or fractures were noted. Coprological assessment demonstrated infection by several gastrointestinal parasites commonly reported in living wild chimpanzees. Histopathology revealed eosinophilic enteritis and biliary hyperplasia potentially caused by parasite infection. However, eosinophilia was not widely spread into the submucosa, while egg/cyst counts suggested low-intensity parasite infections compared to healthy female chimpanzees of similar age in nearby Budongo Forest. No behavioral indicators of ill health were noted in the deceased female in the month prior to the accident. We conclude that cause of death was acute, i.e., shock from the collision, and was probably unrelated to parasite infection or any other underlying health condition. Notably, this female had asymmetrical polythelia, and, while nursing at the time of her death, had one functioning mammary gland only. In Uganda, where primates often inhabit human-dominated landscapes, human population growth and economic development has given rise to increasing motor traffic, while road development is enabling motorists to travel at greater speeds. Thus, the danger of roads to apes and other wildlife is rising, necessitating urgent strategies to reduce risks. Installation of simple speed-bumps-common on Ugandan

  2. The Role of "Islamic feminism" in Somali Immigrant Women's Intra-and Extra-Household Bargaining Power and in Mitigating the Negative Effects of the Image Problem in their Integration in Norway

    OpenAIRE

    Ngunjiri, Anne Wangui

    2013-01-01

    This research explores the aspirations and life experiences of Somali immigrant women in Bergen as they embark on gender-tuned interpretation of the Quran as a source of bargaining power within the household and in the wider Norwegian immigration context. By bargaining power I mean an individual's interests or preferences and the ability to act on those interests or preferences. I show that, faced by constraints such as restrictive structures within the Norwegian immigration context and pa...

  3. IIB solutions with N>28 Killing spinors are maximally supersymmetric

    International Nuclear Information System (INIS)

    Gran, U.; Gutowski, J.; Papadopoulos, G.; Roest, D.

    2007-01-01

    We show that all IIB supergravity backgrounds which admit more than 28 Killing spinors are maximally supersymmetric. In particular, we find that for all N>28 backgrounds the supercovariant curvature vanishes, and that the quotients of maximally supersymmetric backgrounds either preserve all 32 or N<29 supersymmetries

  4. Denaturation of membrane proteins and hyperthermic cell killing

    NARCIS (Netherlands)

    Burgman, Paulus Wilhelmus Johannes Jozef

    1993-01-01

    Summarizing: heat induced denaturation of membrane proteins is probably related to hyperthermic cell killing. Induced resistance of heat sensitive proteins seems to be involved in the development of thermotolerance. Although many questions remain still to be answered, it appears that HSP72, when

  5. Self-dual metrics with self-dual Killing vectors

    International Nuclear Information System (INIS)

    Tod, K.P.; Ward, R.S.

    1979-01-01

    Twistor methods are used to derive a class of solutions to Einstein's vacuum equations, with anti-self dual Weyl tensor. In particular, all metrics with a Killing vector whose derivative is anti-self-dual and which admit a real positive-definite section are exhibited and shown to coincide with the metrics of Hawking. (author)

  6. Prevent Tipping Furniture from Injuring or Killing Young Children

    Science.gov (United States)

    ... more upsetting than the sudden death of a child — killed by a piece of a furniture, appliance or a television falling on them. “It can happen in a ... be secured. Check with home improvement stores or child retail stores and ask experts what they ... television and computer equipment low to the ground. Do ...

  7. Kill Shakespeare – This Bard contains graphic language!

    Directory of Open Access Journals (Sweden)

    Mauro Gentile

    2017-11-01

    Full Text Available Today, adapting Shakespearean plays into comic books or graphic novels appears to be a well-established literary practice in contemporary storytelling. One of the most interesting examples is ÒKill ShakespeareÓ, a graphic novel written by Anthony Del Col and Conor McCreery and illustrated by Andy Belanger. In ÒKill ShakespeareÓ, the authors abandon the idea of adapting a single play to create a Shakespearian mashup in which Hamlet and Juliet fight such villains as Richard III and Lady Macbeth who try to kill a wizard named William Shakespeare.This is the premise for a compelling narration that intertwines various elements of the Shakespearean tradition and attempts to convey an idea of Elizabethan language to contemporary readers. While the characters are familiar, the quest is wholly new and triggers a series of transformations in the narrative, turning upside down the well-established images of Hamlet, Juliet and Othello. Beside the intriguing depictions of the female characters, especially Lady Macbeth,whose image poses questions about the representation of women in comic books, one of the most fertile narrative elements in Kill Shakespeare is the actual presence of William Shakespeare as a character. In conclusion, Del Col and McCreery prove they know their Shakespeare, surprising readers with a fresh approach which, hopefully, will enlarge the Shakespearean audience.

  8. Efficacy of Killed Adjuvanted FMD Vaccine Developed with ...

    African Journals Online (AJOL)

    In this study the potency of killed Foot and Mouth Disease (FMD) vaccines serotypes SAT1 (Nig 1/98) and SAT 2 (Nig 2/97) virus isolates, formulated with montanide ISA 206 adjuvant was determined in guinea pigs and cattle by antibody assay using Complement Fixation and Serum Neutralization tests. The antibody titres ...

  9. Dynamics of Human Complement–Mediated Killing of Klebsiella pneumoniae

    Science.gov (United States)

    Nypaver, Christina M.; Thornton, Margaret M.; Yin, Suellen M.; Bracho, David O.; Nelson, Patrick W.; Jones, Alan E.; Bortz, David M.; Younger, John G.

    2010-01-01

    With an in vitro system that used a luminescent strain of Klebsiella pneumoniae to assess bacterial metabolic activity in near-real-time, we investigated the dynamics of complement-mediated attack in healthy individuals and in patients presenting to the emergency department with community-acquired severe sepsis. A novel mathematical/statistical model was developed to simplify light output trajectories over time into two fitted parameters, the rate of complement activation and the delay from activation to the onset of killing. Using Factor B–depleted serum, the alternative pathway was found to be the primary bactericidal effector: In the absence of B, C3 opsonization as measured by flow cytometry did not progress and bacteria proliferated near exponentially. Defects in bacterial killing were easily demonstrable in patients with severe sepsis compared with healthy volunteers. In most patients with sepsis, the rate of activation was higher than in normal subjects but was associated with a prolonged delay between activation and bacterial killing (P < 0.05 for both). Theoretical modeling suggested that this combination of accentuated but delayed function should allow successful bacterial killing but with significantly greater complement activation. The use of luminescent bacteria allowed for the development of a novel and powerful tool for assessing complement immunology for the purposes of mechanistic study and patient evaluation. PMID:20008281

  10. Dynamics of human complement-mediated killing of Klebsiella pneumoniae.

    Science.gov (United States)

    Nypaver, Christina M; Thornton, Margaret M; Yin, Suellen M; Bracho, David O; Nelson, Patrick W; Jones, Alan E; Bortz, David M; Younger, John G

    2010-11-01

    With an in vitro system that used a luminescent strain of Klebsiella pneumoniae to assess bacterial metabolic activity in near-real-time, we investigated the dynamics of complement-mediated attack in healthy individuals and in patients presenting to the emergency department with community-acquired severe sepsis. A novel mathematical/statistical model was developed to simplify light output trajectories over time into two fitted parameters, the rate of complement activation and the delay from activation to the onset of killing. Using Factor B-depleted serum, the alternative pathway was found to be the primary bactericidal effector: In the absence of B, C3 opsonization as measured by flow cytometry did not progress and bacteria proliferated near exponentially. Defects in bacterial killing were easily demonstrable in patients with severe sepsis compared with healthy volunteers. In most patients with sepsis, the rate of activation was higher than in normal subjects but was associated with a prolonged delay between activation and bacterial killing (P < 0.05 for both). Theoretical modeling suggested that this combination of accentuated but delayed function should allow successful bacterial killing but with significantly greater complement activation. The use of luminescent bacteria allowed for the development of a novel and powerful tool for assessing complement immunology for the purposes of mechanistic study and patient evaluation.

  11. What Is John Dewey Doing in "To Kill a Mockingbird"?

    Science.gov (United States)

    Frank, Jeff

    2015-01-01

    Harper Lee's novel "To Kill a Mockingbird" is taught in countless public schools and is beloved by many teachers and future teachers. Embedded within this novel--interestingly--is a strong criticism of an approach to education mockingly referred to as the "Dewey Decimal System." In this essay I explore Lee's criticism of…

  12. Developing a Critical Literacy Approach with "To Kill a Mockingbird."

    Science.gov (United States)

    Spires, Marian

    2000-01-01

    Ponders why the novel "To Kill a Mockingbird" has held a place in the secondary school canon for 40 years. Describes a 10-week unit for year 10 English students that takes a critical literacy approach to the novel. Outlines a set of pre-reading activities, during reading activities and post-reading activities. (SR)

  13. Suppression of mouse-killing in rats following irradiation

    International Nuclear Information System (INIS)

    O'Boyle, M.

    1976-01-01

    Suppression of mouse-killing was produced following pairings of mouse-presentations (CS) with 96 roentgens of ionizing radiation (US) at 0 (less than 2 min.) and 30 min. US-CS interstimulus intervals. No suppression was found at CS-US intervals of 30 min., 1 hr., and 2 hr., or at US-CS intervals of 1 hr. and 2 hr

  14. Fish Kill in the Philippines—Déjà Vu

    Directory of Open Access Journals (Sweden)

    Gil Jacinto

    2011-12-01

    Full Text Available Almost ten years ago today, the country woke up toscreaming headlines— “Massive Fish Kill inPangasinan” or something akin to that. The fish killphenomenon, familiar to fishers in freshwater andcoastal bodies of water where fish farming was beingpursued, was suddenly manifested at a scale that hadheretofore not been experienced.

  15. The algebra of Killing vectors in five-dimensional space

    International Nuclear Information System (INIS)

    Rcheulishvili, G.L.

    1990-01-01

    This paper presents algebras which are formed by the found earlier Killing vectors in the space with linear element ds. Under some conditions, an explicit dependence of r is given for the functions entering in linear element ds. The curvature two-forms are described. 7 refs

  16. Killing for Girls: Predation Play and Female Empowerment

    Science.gov (United States)

    Bertozzi, Elena

    2012-01-01

    Predation games--games in which the player is actively encouraged and often required to hunt and kill in order to survive--have historically been the purview of male players. Females, though now much more involved in digital games than before, generally play games that stress traditionally feminine values such as socializing with others, shopping,…

  17. Targeted killing with drones? Old arguments, new technologies

    Directory of Open Access Journals (Sweden)

    Meisels Tamar

    2018-01-01

    Full Text Available The question of how to contend with terrorism in keeping with our preexisting moral and legal commitments now challenges Europe as well as Israel and the United States: how do we apply Just War Theory and International Law to asymmetrical warfare, specifically to our counter terrorism measures? What can the classic moral argument in Just and Unjust Wars teach us about contemporary targeted killings with drones? I begin with a defense of targeted killing, arguing for the advantages of pin pointed attacks over any alternative measure available for combatting terrorism. Assuming the legitimacy of killing combatants in wartime, I argue, there is nothing wrong, and in fact much that is right, with targeting particular terrorists selected by name, as long as their assassinations can be reasonably expected to reduce terrorist hostilities rather than increase it. Subsequently, I offer some further thoughts and comments on the use of remotely piloted aircrafts to carry out targeted killings, and address the various sources for discomfort with this practice identified by Michael Walzer and others.

  18. Partner Killing by Men in Cohabiting and Marital Relationships

    Science.gov (United States)

    Shackelford, Todd K.; Mouzos, Jenny

    2005-01-01

    Using a national-level U.S. database, T. K. Shackelford (2001) calculated rates of uxoricide (the murder of a woman by her romantic partner) by relationship type (cohabiting or marital), by ages of the partners, and by the age difference between partners. Women in cohabiting relationships were 9 times more likely to be killed by their partner than…

  19. Nordic Noir on Television: The Killing I-III

    DEFF Research Database (Denmark)

    Agger, Gunhild

    2012-01-01

    The Nordic Noir has been applied by many countries as a slightly distorting mirror of tendencies in their own societies. On the background of its international appeal, the article analyses the prevalent genre of The Killing – the thriller – and relates it to the genres of crime fiction, political...

  20. Pseudomonas Exotoxin A: optimized by evolution for effective killing

    Directory of Open Access Journals (Sweden)

    Marta eMichalska

    2015-09-01

    Full Text Available Pseudomonas Exotoxin A (PE is the most toxic virulence factor of the pathogenic bacterium Pseudomonas aeruginosa. This review describes current knowledge about the intoxication pathways of PE. Moreover, PE represents a remarkable example for pathoadaptive evolution, how bacterial molecules have been structurally and functionally optimized under evolutionary pressure to effectively impair and kill their host cells.

  1. Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

    DEFF Research Database (Denmark)

    Makarov, Vadim; Manina, Giulia; Mikusova, Katarina

    2009-01-01

    New drugs are required to counter the tuberculosis (TB) pandemic. Here, we describe the synthesis and characterization of 1,3-benzothiazin-4-ones (BTZs), a new class of antimycobacterial agents that kill Mycobacterium tuberculosis in vitro, ex vivo, and in mouse models of TB. Using genetics...

  2. Illegal killing for ivory drives global decline in African elephants.

    Science.gov (United States)

    Wittemyer, George; Northrup, Joseph M; Blanc, Julian; Douglas-Hamilton, Iain; Omondi, Patrick; Burnham, Kenneth P

    2014-09-09

    Illegal wildlife trade has reached alarming levels globally, extirpating populations of commercially valuable species. As a driver of biodiversity loss, quantifying illegal harvest is essential for conservation and sociopolitical affairs but notoriously difficult. Here we combine field-based carcass monitoring with fine-scale demographic data from an intensively studied wild African elephant population in Samburu, Kenya, to partition mortality into natural and illegal causes. We then expand our analytical framework to model illegal killing rates and population trends of elephants at regional and continental scales using carcass data collected by a Convention on International Trade in Endangered Species program. At the intensively monitored site, illegal killing increased markedly after 2008 and was correlated strongly with the local black market ivory price and increased seizures of ivory destined for China. More broadly, results from application to continental data indicated illegal killing levels were unsustainable for the species between 2010 and 2012, peaking to ∼ 8% in 2011 which extrapolates to ∼ 40,000 elephants illegally killed and a probable species reduction of ∼ 3% that year. Preliminary data from 2013 indicate overharvesting continued. In contrast to the rest of Africa, our analysis corroborates that Central African forest elephants experienced decline throughout the last decade. These results provide the most comprehensive assessment of illegal ivory harvest to date and confirm that current ivory consumption is not sustainable. Further, our approach provides a powerful basis to determine cryptic mortality and gain understanding of the demography of at-risk species.

  3. In vitro time kill assessment of crude methanol extract of ...

    African Journals Online (AJOL)

    The in vitro antibacterial activities and time kill regimes of crude methanol extract of Helichrysum pedunculatum was assessed using standard microbiological procedures. The experiment was conducted against a panel of bacterial species made up of clinical, environmental and reference strains. The extract was active ...

  4. [Killing effect of polymorphonuclear neutrophils on Trichomonas vaginalis].

    Science.gov (United States)

    Zhao, Jian-Ling; Gao, Xing-Zheng; Qu, Ming

    2008-10-30

    To study the killing effect of polymorphonuclear neutrophils (PMNs) on Trichomonas vaginalis. The vaginal secretion from a patient with vaginitis was incubated in the liver infusion liquid medium to get T. vaginalis. One ml serum was collected from the patient and heated for 30 min at 56 degrees C to inactivate complement in serum, and was absorbed three times with the parasites at 0 degree C to make the serum free of antibodies. PMNs were separated from the patient's blood and purified with density gradient centrifugation and polymer accelerating sedimentation. NBT and safranin O were used to stain the sample. The interaction between PMNs and the parasites was observed under microscope. 300 trichomonads and 3x10(4) PMNs were incubated for 10, 20, 30, 40, 50, 60 minutes under the conditions of aerobic or anaerobic, with superoxide dismutase (SOD) and catalase (CAT) or without SOD and CAT, and with complement or without complement. They were then inoculated in solid medium for another five days under the anaerobic condition, and surviving organisms were enumerated. PMNs were observed to surround and kill a single trichomonad. In the petri-dish containing PMNs, the surviving rate of the parasites in anaerobic condition was 85%, only 3% in aerobic condition (P<0.01). SOD and CAT reduced the killing effect of PMNs, with a surviving rate of 98% and 94% respectively after 60 min incubation. Without SOD and CAT, the surviving rate is only 2% (P<0.05). PMNs in the serum without antibodies killed all the parasites, while the complement-inactivated serum fail to kill them. The trichomonacidal activity of PMNs relies on the presence of oxygen and complement in the serum of patient.

  5. How Piracy is Affecting Economic Development in Puntland, Somalia

    Directory of Open Access Journals (Sweden)

    Jonathan R. Beloff

    2013-01-01

    Full Text Available The international community has united in its mission to halt the hijacking of merchant ships in the Gulf of Aden and the Red Sea with a massive naval presence that monitors the vast, strategic seas in which Somali pirates operate. This naval presence consequently has had some success in reducing pirate attacks in 2012, but why are the Somalis turning to piracy in the first place? The economic history of piracy has been well documented with other former “pirate hotspots” worldwide; however, there is little data available on the microeconomic affects of piracy. This article explores the underlying reasons of why Somalis have turned to piracy as a “profession,” and offers recommendations for the international community to eliminate piracy effectively through non-military means.

  6. Broadening the future of value account of the wrongness of killing

    DEFF Research Database (Denmark)

    Di Nucci, Ezio

    2015-01-01

    On Don Marquis's future of value account of the wrongness of killing, 'what makes it wrong to kill those individuals we all believe it is wrong to kill, is that killing them deprives them of their future of value'. Marquis has recently argued for a narrow interpretation of his future of value...... account of the wrongness of killing and against the broad interpretation that I had put forward in response to Carson Strong. In this article I argue that the narrow view is problematic because it violates some basic principles of equality and because it allows for some of the very killing that Marquis...

  7. Male-killing bacteria as agents of insect pest control

    International Nuclear Information System (INIS)

    Berec, Ludek; Maxin, Daniel; Bernhauerová, Veronika

    2016-01-01

    1. Continual effort is needed to reduce the impact of exotic species in the context of increased globalization. Any innovation in this respect would be an asset. 2. We assess the potential of combining two pest control techniques: the well-established sterile insect technique (SIT) and a novel male-killing technique (MKT), which comprises inoculation of a pest population with bacteria that kill the infected male embryos. 3. Population models are developed to assess the efficiency of using the MKT for insect pest control, either alone or together with the SIT. We seek for conditions under which the MKT weakens requirements on the SIT. 4. Regarding the SIT, we consider both non-heritable and inherited sterility. In both cases, the MKT and SIT benefit one another. The MKT may prevent the SIT from failing when not enough sterilized males are released due to high production costs and/or uncertainty on their mating ability following a high irradiation dose. Conversely, with already established SIT, pest eradication can be achieved after introduction of male-killing bacteria with lower vertical transmission efficiency than if the MKT was applied alone. 5. For tephritid fruit flies with non-heritable sterility, maximal impact of the SIT is achieved when the released males are fully sterile. Conversely, for lepidopterans with inherited sterility, maximal impact of the SIT is achieved for intermediate irradiation doses. In both cases, increasing vertical transmission efficiency of male-killing bacteria benefits the SIT; high enough vertical transmission efficiency allows for pest eradication where the SIT is absent or induces only pest suppression when used alone. 6. Synthesis and applications. While both techniques can suppress or eliminate the pest on their own, combined application of the male-killing technique and the sterile insect technique substantially increases pest control efficiency. If male-killing bacteria are already established in the pest, any assessment of

  8. The effect of kleptoparasitic bald eagles and gyrfalcons on the kill rate of peregrine falcons hunting dunlins wintering in British Columbia

    NARCIS (Netherlands)

    Dekker, T.J.; Out, M.; Tabak, M.; Ydenberg, R.C.

    2012-01-01

    Kleptoparasitism in birds has been the subject of much research, and the Bald Eagle (Haliaeetus leucocephalus) is a known kleptoparasite. It has been reported to pirate ducks captured by Peregrine Falcons (Falco peregrinus), but ours is the first study to examine the effect of kleptoparasitic Bald

  9. Scientific projection paper for mutagenesis, transformation and cell killing

    International Nuclear Information System (INIS)

    Todd, P.

    1980-01-01

    Our knowledge about mutagenesis, transformation, and cell killing by ionizing radiation consists of large bodies of data, which are potentially useful in terms of application to human risk assessment and to the constructive use of radiation, as in cancer treatment. The three end-points discussed above are united by at least five significant concepts in radiation research strategy: (1) The inter-relationships among the important end-points, mutation, carcinogenesis, and cell killing. Research on one is meaningful only in the context of information about the other two. (2) The interaction of radiations with other agents in producing these end-points. (3) The mechanisms of action of other environmental mutagenic, carcinogenic, and cytotoxic agents. (4) The use of repair deficient human mutant cells. (5) The study of radiation damage mechanisms. There is no better way to extrapolate laboratory data to the clinical and public worlds than to understand the underlying biological mechanisms that produced the data

  10. "Reversed" intraguild predation: red fox cubs killed by pine marten.

    Science.gov (United States)

    Brzeziński, Marcin; Rodak, Lukasz; Zalewski, Andrzej

    2014-01-01

    Camera traps deployed at a badger Meles meles set in mixed pine forest in north-eastern Poland recorded interspecific killing of red fox Vulpes vulpes cubs by pine marten Martes martes . The vixen and her cubs settled in the set at the beginning of May 2013, and it was abandoned by the badgers shortly afterwards. Five fox cubs were recorded playing in front of the den each night. Ten days after the first recording of the foxes, a pine marten was filmed at the set; it arrived in the morning, made a reconnaissance and returned at night when the vixen was away from the set. The pine marten entered the den several times and killed at least two fox cubs. It was active at the set for about 2 h. This observation proves that red foxes are not completely safe from predation by smaller carnivores, even those considered to be subordinate species in interspecific competition.

  11. Kill ratio calculation for in-line yield prediction

    Science.gov (United States)

    Lorenzo, Alfonso; Oter, David; Cruceta, Sergio; Valtuena, Juan F.; Gonzalez, Gerardo; Mata, Carlos

    1999-04-01

    The search for better yields in IC manufacturing calls for a smarter use of the vast amount of data that can be generated by a world class production line.In this scenario, in-line inspection processes produce thousands of wafer maps, number of defects, defect type and pictures every day. A step forward is to correlate these with the other big data- generator area: test. In this paper, we present how these data can be put together and correlated to obtain a very useful yield predicting tool. This correlation will first allow us to calculate the kill ratio, i.e. the probability for a defect of a certain size in a certain layer to kill the die. Then we will use that number to estimate the cosmetic yield that a wafer will have.

  12. Great tits search for, capture, kill and eat hibernating bats

    Science.gov (United States)

    Estók, Péter; Zsebők, Sándor; Siemers, Björn M.

    2010-01-01

    Ecological pressure paired with opportunism can lead to surprising innovations in animal behaviour. Here, we report predation of great tits (Parus major) on hibernating pipistrelle bats (Pipistrellus pipistrellus) at a Hungarian cave. Over two winters, we directly observed 18 predation events. The tits specifically and systematically searched for and killed bats for food. A substantial decrease in predation on bats after experimental provisioning of food to the tits further supports the hypothesis that bat-killing serves a foraging purpose in times of food scarcity. We finally conducted a playback experiment to test whether tits would eavesdrop on calls of awakening bats to find them in rock crevices. The tits could clearly hear the calls and were attracted to the loudspeaker. Records for tit predation on bats at this cave now span more than ten years and thus raise the question of whether cultural transmission plays a role for the spread of this foraging innovation. PMID:19740892

  13. A Research for Massive Fish Kills in Lake Bafa (Turkey

    Directory of Open Access Journals (Sweden)

    Murat Yabanlı

    2011-06-01

    Full Text Available As there were massive fish kills in Lake Bafa which is a lagoon situated in Southwestern Turkey in October, 2006, water and fish samples were taken from the region. Water samples were analysed physicochemically, toxicologically and microbiologically and fish samples were subjected to toxicological analysis. The analyses of lake water revealed on oxygen value of approximately 5.0 mg/L, salinity 16.2 ‰, nitrogen from ammonia 0.1 mg/L, nitrogen nitrite 0.013 mg/L, and total organic carbon 13 mg/L. Total coliform count was 1100 MPN/100 ml and faecal coliform count was 28 MPN/100 ml. There was no detection of any pesticide residues in fish and water samples. Massive fish kills are thought to be due to the decrease in water quality.

  14. The killing of African trypanosomes by ethidium bromide.

    Directory of Open Access Journals (Sweden)

    Arnab Roy Chowdhury

    2010-12-01

    Full Text Available Introduced in the 1950s, ethidium bromide (EB is still used as an anti-trypanosomal drug for African cattle although its mechanism of killing has been unclear and controversial. EB has long been known to cause loss of the mitochondrial genome, named kinetoplast DNA (kDNA, a giant network of interlocked minicircles and maxicircles. However, the existence of viable parasites lacking kDNA (dyskinetoplastic led many to think that kDNA loss could not be the mechanism of killing. When recent studies indicated that kDNA is indeed essential in bloodstream trypanosomes and that dyskinetoplastic cells survive only if they have a compensating mutation in the nuclear genome, we investigated the effect of EB on kDNA and its replication. We here report some remarkable effects of EB. Using EM and other techniques, we found that binding of EB to network minicircles is low, probably because of their association with proteins that prevent helix unwinding. In contrast, covalently-closed minicircles that had been released from the network for replication bind EB extensively, causing them, after isolation, to become highly supertwisted and to develop regions of left-handed Z-DNA (without EB, these circles are fully relaxed. In vivo, EB causes helix distortion of free minicircles, preventing replication initiation and resulting in kDNA loss and cell death. Unexpectedly, EB also kills dyskinetoplastic trypanosomes, lacking kDNA, by inhibiting nuclear replication. Since the effect on kDNA occurs at a >10-fold lower EB concentration than that on nuclear DNA, we conclude that minicircle replication initiation is likely EB's most vulnerable target, but the effect on nuclear replication may also contribute to cell killing.

  15. Targeted Killing: Managing American Perceptions On Unmanned Aerial Vehicle Operations

    Science.gov (United States)

    2016-02-01

    Requirements Proposal Advisor: Dr. Patricia Williams Lessane Project Advisor: Dr. Andrew Niesiobedzki Maxwell AFB, AL February 2016...epistemology of remote fighting." Ethics and Information Technology 15. no. 2. 87-98. Cullen , Peter. 2008. "The Role of Targeted Killing in the...in the Sky." New Statesman 19-25. June. 48. Patterson, Margot. 2015. "Are We Safer." America 212. no. 204. 12. Raven-Hansen, William C. Banks and

  16. Comments on conformal Killing vector fields and quantum field theory

    International Nuclear Information System (INIS)

    Brown, M.R.; Ottewill, A.C.; Siklos, S.T.C.

    1982-01-01

    We give a comprehensive analysis of those vacuums for flat and conformally flat space-times which can be defined by timelike, hypersurface-orthogonal, conformal Killing vector fields. We obtain formulas for the difference in stress-energy density between any two such states and display the correspondence with the renormalized stress tensors. A brief discussion is given of the relevance of these results to quantum-mechanical measurements made by noninertial observers moving through flat space

  17. Midgut microbiota and host immunocompetence underlie Bacillus thuringiensis killing mechanism

    OpenAIRE

    Caccia, Silvia; Di Lelio, Ilaria; La Storia, Antonietta; Marinelli, Adriana; Varricchio, Paola; Franzetti, Eleonora; Banyuls, Núria; Tettamanti, Gianluca; Casartelli, Morena; Giordana, Barbara; Ferré, Juan; Gigliotti, Silvia; Ercolini, Danilo; Pennacchio, Francesco

    2016-01-01

    Bacillus thuringiensis and its toxins are widely used for insect control. Notwithstanding the remarkable importance of this insect pathogen, its killing mechanism has yet to be fully elucidated. Here we show that the microbiota resident in the host midgut triggers a lethal septicemia. The infection process is enhanced by reducing the host immune response and its control on replication of midgut bacteria invading the body cavity through toxin-induced epithelial lesions. The experimental approa...

  18. Does Host Complement Kill Borrelia burgdorferi within Ticks?

    OpenAIRE

    Rathinavelu, Sivaprakash; Broadwater, Anne; de Silva, Aravinda M.

    2003-01-01

    The Lyme disease spirochete, Borrelia burgdorferi, inhabits the gut lumen of the tick vector. At this location the spirochete is exposed to host blood when a tick feeds. We report here on studies that were done with normal and complement-deficient (C3-knockout) mice to determine if the host complement system killed spirochetes within the vector. We found that spirochete numbers within feeding nymphs were not influenced by complement, most likely because host complement was inactivated within ...

  19. Shearfree congruences of null geodesics and Killing tensors

    International Nuclear Information System (INIS)

    Dietz, W.; Ruediger, R.

    1980-01-01

    In this communication, the mutual connections between quantities that are generalizations of the notion of a a Killing vector field are investigated. A classification of these quantities in terms of a complex vector field αsub(a) is given. A common feature of all these quantities is that they imply the existence of a pair of shearfree geodetic null congruences. There are no explicit restrictions posed on the Ricci tensor. (author)

  20. From Attitudes to Actions: Predictors of Lion Killing by Maasai Warriors.

    Science.gov (United States)

    Hazzah, Leela; Bath, Alistair; Dolrenry, Stephanie; Dickman, Amy; Frank, Laurence

    2017-01-01

    Despite legal protection, deliberate killing by local people is one of the major threats to the conservation of lions and other large carnivores in Africa. Addressing this problem poses particular challenges, mainly because it is difficult to uncover illicit behavior. This article examined two groups of Maasai warriors: individuals who have killed African lions (Panthera leo) and those who have not. We conducted interviews to explore the relationship between attitudes, intentions and known lion killing behavior. Factor analysis and logistic regression revealed that lion killing was mainly determined by: (a) general attitudes toward lions, (b) engagement in traditional customs, (c) lion killing intentions to defend property, and (d) socio-cultural killing intentions. Our results indicated that general attitudes toward lions were the strongest predictor of lion killing behavior. Influencing attitudes to encourage pro-conservation behavior may help reduce killing.

  1. Leadership Matters : The Effects of Targeted Killings on Militant Group Tactics

    NARCIS (Netherlands)

    Abrahms, Max; Mierau, Jochen

    2017-01-01

    Targeted killings have become a central component of counter-terrorism strategy. In response to the unprecedented prevalence of this strategy around the world, numerous empirical studies have recently examined whether "decapitating" militant groups with targeted killings is strategically effective.

  2. Default risk modeling with position-dependent killing

    Science.gov (United States)

    Katz, Yuri A.

    2013-04-01

    Diffusion in a linear potential in the presence of position-dependent killing is used to mimic a default process. Different assumptions regarding transport coefficients, initial conditions, and elasticity of the killing measure lead to diverse models of bankruptcy. One “stylized fact” is fundamental for our consideration: empirically default is a rather rare event, especially in the investment grade categories of credit ratings. Hence, the action of killing may be considered as a small parameter. In a number of special cases we derive closed-form expressions for the entire term structure of the cumulative probability of default, its hazard rate, and intensity. Comparison with historical data on aggregate global corporate defaults confirms the validity of the perturbation method for estimations of long-term probability of default for companies with high credit quality. On a single company level, we implement the derived formulas to estimate the one-year likelihood of default of Enron on a daily basis from August 2000 to August 2001, three months before its default, and compare the obtained results with forecasts of traditional structural models.

  3. Killing effect of carboranyl uridine on boron neutron capture reaction

    International Nuclear Information System (INIS)

    Takagaki, M.; Oda, Y.; Zhang, Z.

    1994-01-01

    This paper deals with the killing effect of carboranyl uridine (CU) on thermal neutron capture reaction in cultured glioma cell line (C6). The tumoricidal effect of CU for boron neutron capture therapy in the cultured cell system is presented. To assess the uptake of CU, the number of germ cells was determined by comparing protein concentrations of C6 cells in vitro with that of intracranially transplanted C6 tumor cells in vivo. To assess tumoricidal effects of CU, human glioma cells (T98G), containing 25 ppm natural boron of CU, were irradiated with various doses of thermal neutrons at a constant fluence rate. The uptake and killing effects of mercaptoboron and boric acid were also investigated as controls. Subcellular boron concentrations confirmed the selective affinity to the nucleic acid synthesis. CU was found to have an affinity to nucleic acid synthesis and to be accumulated into nucleus of tumor cells. The irradiation dose which yielded 37% survival rate in the case of CU and control were 3.78+12E nvt and 5.80+12E nvt, respectively. The killing effect of CU was slightly higher than that of B-SH or BA. The effective way of CU injection should be further studied to obtain the uniform CU uptake in tumor cells. (N.K.)

  4. Intestinal mucus protects Giardia lamblia from killing by human milk.

    Science.gov (United States)

    Zenian, A J; Gillin, F D

    1987-02-01

    We have previously shown that nonimmune human milk kills Giardia lamblia trophozoites in vitro. Killing requires a bile salt and the activity of the milk bile salt-stimulated lipase. We now show that human small-intestinal mucus protects trophozoites from killing by milk. Parasite survival increased with mucus concentration, but protection was overcome during longer incubation times or with greater milk concentrations. Trophozoites preincubated with mucus and then washed were not protected. Protective activity was associated with non-mucin CsCl density gradient fractions. Moreover, it was heat-stable, non-dialyzable, and non-lipid. Whereas whole mucus inhibited milk lipolytic activity, protective mucus fractions did not inhibit the enzyme. Furthermore, mucus partially protected G. lamblia trophozoites against the toxicity of oleic acid, a fatty acid which is released from milk triglycerides by lipase. These studies show that mucus protects G. lamblia both by inhibiting lipase activity and by decreasing the toxicity of products of lipolysis. The ability of mucus to protect G. lamblia from toxic lipolytic products may help to promote intestinal colonization by this parasite.

  5. Photoexcited quantum dots for killing multidrug-resistant bacteria

    Science.gov (United States)

    Courtney, Colleen M.; Goodman, Samuel M.; McDaniel, Jessica A.; Madinger, Nancy E.; Chatterjee, Anushree; Nagpal, Prashant

    2016-05-01

    Multidrug-resistant bacterial infections are an ever-growing threat because of the shrinking arsenal of efficacious antibiotics. Metal nanoparticles can induce cell death, yet the toxicity effect is typically nonspecific. Here, we show that photoexcited quantum dots (QDs) can kill a wide range of multidrug-resistant bacterial clinical isolates, including methicillin-resistant Staphylococcus aureus, carbapenem-resistant Escherichia coli, and extended-spectrum β-lactamase-producing Klebsiella pneumoniae and Salmonella typhimurium. The killing effect is independent of material and controlled by the redox potentials of the photogenerated charge carriers, which selectively alter the cellular redox state. We also show that the QDs can be tailored to kill 92% of bacterial cells in a monoculture, and in a co-culture of E. coli and HEK 293T cells, while leaving the mammalian cells intact, or to increase bacterial proliferation. Photoexcited QDs could be used in the study of the effect of redox states on living systems, and lead to clinical phototherapy for the treatment of infections.

  6. Effects of lead on the killing mechanisms of polymorphonuclear leukocytes

    International Nuclear Information System (INIS)

    Silberstein, C.F.

    1984-01-01

    The effects of lead on the killing mechanisms of rat polymorphonuclear leukocytes (PMN) were investigated, using male Long-Evans rats exposed to 1% lead acetate in the drinking water for varying periods of time to achieve blood lead levels ranging from 20-200 μg/dl. Studies of PMN bacterial and fungal killing activity, chemotaxis and phagocytosis demonstrated that: 1) bactericidal activity of PMN from rats exposed to lead was not altered; 2) chemotactic activity remained within normal limits; 3) the phagocytic ability of the PMN also remained unaltered. In addition to these normal findings, one major abnormality was demonstrated: a significant decrease in the ability of PMN from rats exposed to lead to kill Candida albicans. This defect was not related to age or to length of exposure. It could not be produced by addition of lead to the test system in vitro. Further investigation revealed significant decreases in PMN glucose-6-phosphate dehydrogenase, catalase, and myeloperoxidase activities. These data support two possible mechanisms for the abnormal fungicidal activity of PMN from lead-exposed rats: decrease in ability to reduce oxygen to active metabolites, or reduction in myeloperoxidase activity due to diminshed synthesis of the heme moiety required for its function

  7. Polyanhydride Nanoparticle Delivery Platform Dramatically Enhances Killing of Filarial Worms.

    Directory of Open Access Journals (Sweden)

    Andrea M Binnebose

    Full Text Available Filarial diseases represent a significant social and economic burden to over 120 million people worldwide and are caused by endoparasites that require the presence of symbiotic bacteria of the genus Wolbachia for fertility and viability of the host parasite. Targeting Wolbachia for elimination is a therapeutic approach that shows promise in the treatment of onchocerciasis and lymphatic filariasis. Here we demonstrate the use of a biodegradable polyanhydride nanoparticle-based platform for the co-delivery of the antibiotic doxycycline with the antiparasitic drug, ivermectin, to reduce microfilarial burden and rapidly kill adult worms. When doxycycline and ivermectin were co-delivered within polyanhydride nanoparticles, effective killing of adult female Brugia malayi filarial worms was achieved with approximately 4,000-fold reduction in the amount of drug used. Additionally the time to death of the macrofilaria was also significantly reduced (five-fold when the anti-filarial drug cocktail was delivered within polyanhydride nanoparticles. We hypothesize that the mechanism behind this dramatically enhanced killing of the macrofilaria is the ability of the polyanhydride nanoparticles to behave as a Trojan horse and penetrate the cuticle, bypassing excretory pumps of B. malayi, and effectively deliver drug directly to both the worm and Wolbachia at high enough microenvironmental concentrations to cause death. These provocative findings may have significant consequences for the reduction in the amount of drug and the length of treatment required for filarial infections in terms of patient compliance and reduced cost of treatment.

  8. It’s Not Just Conflict That Motivates Killing of Orangutans

    Science.gov (United States)

    Davis, Jacqueline T.; Mengersen, Kerrie; Abram, Nicola K.; Ancrenaz, Marc; Wells, Jessie A.; Meijaard, Erik

    2013-01-01

    We investigated why orangutans are being killed in Kalimantan, Indonesia, and the role of conflict in these killings. Based on an analysis of interview data from over 5,000 respondents in over 450 villages, we also assessed the socio-ecological factors associated with conflict and non-conflict killings. Most respondents never kill orangutans. Those who reported having personally killed an orangutan primarily did so for non-conflict reasons; for example, 56% of these respondents said that the reason they had killed an orangutan was to eat it. Of the conflict-related reasons for killing, the most common reasons orangutans were killed was fear of orangutans or in self-defence. A similar pattern was evident among reports of orangutan killing by other people in the villages. Regression analyses indicated that religion and the percentage of intact forest around villages were the strongest socio-ecological predictors of whether orangutans were killed for conflict or non-conflict related reasons. Our data indicate that between 44,170 and 66,570 orangutans were killed in Kalimantan within the respondents’ active hunting lifetimes: between 12,690 and 29,024 for conflict reasons (95%CI) and between 26,361 and 41,688 for non-conflict reasons (95% CI). These findings confirm that habitat protection alone will not ensure the survival of orangutans in Indonesian Borneo, and that effective reduction of orangutan killings is urgently needed. PMID:24130707

  9. Preliminary study of killing the larva of plodia interpunella by irradiation

    International Nuclear Information System (INIS)

    Wang Jide; Ma Xiaoping

    1994-01-01

    The results of killing the larva of plodia interpunella in the fruit by 60 Co γ-irradiation are described. The lowest effective dose for killing larva by irradiation is ca. 2000 Gy; the effective dose for immediately killing larva is 3000 Gy. The method is simple and easy and also suitable for the study of commercial irradiation of dry-fruit

  10. The situation for female survivors of non-partner sexual violence: A focused enquiry of Somali young women's views, knowledge and opinions.

    Science.gov (United States)

    Byrskog, Ulrika; Hussein, Ifrah Hashi; Yusuf, Farah Mohamed; Egal, Jama Ali; Erlandsson, Kerstin

    2018-06-01

    The aim of the study is to elucidate young women's perceptions of the situation for female survivors of non-partner sexual violence in Somaliland. Young Somali women with diverse backgrounds (n = 25) shared views, knowledge and opinions about non partner sexual violence in focus group discussions held in urban settings. Data was analysed using content analysis. A main category "Bound by culture and community perceptions" with four subcategories comprises the informants' perceptions of non-partner sexual violence among young women in Somaliland. Illuminated is the importance of protecting oneself and the family dignity, a fear of being rejected and mistrusted, how the juridical system exists in the shadow of tradition and potential keys to healthcare support. The study raises awareness of the dilemmas which may be faced by young women subjected to non-partner sexual violence and healthcare providers in the intersection between state and traditional norms. Education is a key when it comes to a young woman considering the use of the services available in a society where traditional problem-solving is relied on parallel to state-based support. State-based functions, communities and families need to work together to provide comprehensive support to young female survivors of non-partner sexual violence in Somaliland. Copyright © 2018 Elsevier B.V. All rights reserved.

  11. They Just Respect You for Who You Are: Contributors to Educator Positive Youth Development Promotion for Somali, Latino, and Hmong Students.

    Science.gov (United States)

    Allen, Michele L; Rosas-Lee, Maira; Ortega, Luis; Hang, Mikow; Pergament, Shannon; Pratt, Rebekah

    2016-02-01

    Youth from immigrant communities may experience barriers to connecting with schools and teachers, potentially undermining academic achievement and healthy youth development. This qualitative study aimed to understand how educators serving Somali, Latino, and Hmong (SLH) youth can best promote educator-student connectedness and positive youth development, by exploring the perspectives of teachers, youth workers, and SLH youth, using a community based participatory research approach. We conducted four focus groups with teachers, 18 key informant interviews with adults working with SLH youth, and nine focus groups with SLH middle and high school students. Four themes emerged regarding facilitators to educators promoting positive youth development in schools: (1) an authoritative teaching approach where teachers hold high expectations for student behavior and achievement, (2) building trusting educator-student relationships, (3) conveying respect for students as individuals, and (4) a school infrastructure characterized by a supportive and inclusive environment. Findings suggest a set of skills and educator-student interactions that may promote positive youth development and increase student-educator connectedness for SLH youth in public schools.

  12. Development and Pilot Testing of 24-Hour Multiple-Pass Recall to Assess Dietary Intake of Toddlers of Somali- and Iraqi-Born Mothers Living in Norway

    Directory of Open Access Journals (Sweden)

    Navnit Kaur Grewal

    2014-06-01

    Full Text Available The aim of this study was to develop, test, and evaluate a 24-h recall procedure to assess the dietary intake of toddlers of Somali- and Iraqi-born mothers living in Norway. A protocol for a 24-h multiple-pass recall procedure, registration forms, and visual tools (a picture library for food identification and portion size estimation was developed and tested in 12 mothers from Somalia and Iraq with children aged 10–21 months. Five female field workers were recruited and trained to conduct the interviews. Evaluation data for the 24-h recall procedure were collected from both the mothers and the field workers. Nutrient intake was calculated using a Norwegian dietary calculation system. Each child’s estimated energy intake was compared with its estimated energy requirement. Both the mothers and the field workers found the method feasible and the visual tools useful. The estimated energy intake corresponded well with the estimated energy requirement for most of the children (within mean ± 2 SD, except for three. The pilot study identified the need for additional foods in the picture library and some crucial aspects in training and supervising the field workers to reduce sources of error in the data collection.

  13. 40 CFR 180.1108 - Delta endotoxin of Bacillus thuringiensis variety San Diego encapsulated into killed Pseudomonas...

    Science.gov (United States)

    2010-07-01

    ... thuringiensis variety San Diego encapsulated into killed Pseudomonas fluorescens; exemption from the requirement... into killed Pseudomonas fluorescens; exemption from the requirement of a tolerance. The delta endotoxin of Bacillus thuringiensis variety San Diego encapsulated into killed Pseudomonas fluorescens is...

  14. Comparing Road-Kill Datasets from Hunters and Citizen Scientists in a Landscape Context

    OpenAIRE

    Florian Heigl; Carina R. Stretz; Wolfgang Steiner; Franz Suppan; Thomas Bauer; Gregor Laaha; Johann G. Zaller

    2016-01-01

    Road traffic has severe effects on animals, especially when road-kills are involved. In many countries, official road-kill data are provided by hunters or police; there are also road-kill observations reported by citizen scientists. The aim of the current study was to test whether road-kill reports by hunters stem from similar landscapes than those reported by citizen scientists. We analysed the surrounding landscapes of 712 road-kill reportings of European hares in the province of Lower Aust...

  15. Killing in More-than-human Spaces: Pasteurisation, Fungi, and the Metabolic Lives of Wine

    Directory of Open Access Journals (Sweden)

    Brice, Jeremy

    2014-05-01

    Full Text Available What place might killing occupy in a more-than-human world, where human life is always-already entangled among nonhumans? In this article I attempt to unsettle the assumption that only individual organisms can be killed, and to render other sites and spaces of killing visible. Drawing on ethnographic fieldwork among winemakers in South Australia I examine pasteurisation, a killing practice that acts not on organisms but on the fluids within which they live. Examining the pasteurisation of wine damaged by the fungus Botrytis cinerea, I argue that this practice shifts the locus of killing from botrytis’ body to metabolic life processes which embrace extracellular enzymes diffused throughout the wine. I suggest that pasteurisation thus displaces killing into spaces, such as wine-in-the-making, within which many metabolic lives coexist and interpenetrate. Pasteurisation therefore renders killing an intervention into the metabolic relationships that tie together numerous species of microbes living within wine. In acting on wine as a whole it kills rather indiscriminately, simultaneously terminating multiple lives that relate to humans in different ways. Pasteurisation therefore both protects and spoils wine, reconfiguring multiple human-nonhuman relationships in conflicting and sometimes economically costly ways. In so doing, it illustrates that in a more-than-human world killing becomes difficult to confine to a single unwanted organism or species. Killing instead becomes disturbingly mobile and communicable, prone to rebound upon the valued human lives of those who kill in unsettling and potentially harmful ways.

  16. Killed oral cholera vaccines: history, development and implementation challenges.

    Science.gov (United States)

    Lopez, Anna Lena; Gonzales, Maria Liza Antoinette; Aldaba, Josephine G; Nair, G Balakrish

    2014-09-01

    Cholera is still a major global health problem, affecting mainly people living in unsanitary conditions and who are at risk for outbreaks of cholera. During the past decade, outbreaks are increasingly reported from more countries. From the early killed oral cholera vaccine, rapid improvements in vaccine development occurred as a result of a better understanding of the epidemiology of the disease, pathogenesis of cholera infection and immunity. The newer-generation oral killed cholera vaccines have been shown to be safe and effective in field trials conducted in cholera endemic areas. Likewise, they have been shown to be protective when used during outbreak settings. Aside from providing direct protection to vaccinated individuals, recent studies have demonstrated that these killed oral vaccines also confer indirect protection through herd immunity. Although new-generation oral cholera vaccines should not be considered in isolation from other preventive approaches in countries where they are most needed, especially improved water quality and sanitation, these vaccines serve as immediately available public health tools for preventing further morbidity and mortality from cholera. However, despite its availability for more than two decades, use of these vaccines has not been optimized. Although there are limitations of the currently available oral cholera vaccines, recent data show that the vaccines are safe, feasible to use even in difficult circumstances and able to provide protection in various settings. Clear identification of the areas and target population groups who will benefit from the use of the cholera vaccines will be required and strategies to facilitate accessibility and usage of these vaccines in these areas and population groups will need to be developed.

  17. Ground Zero/Fresh Kills: Cataloguing Ruins, Garbage, and Memory

    OpenAIRE

    Cinzia Scarpino

    2011-01-01

    The aim of this paper is to show how the rise and fall of the Twin Towers can be read in relation to the rise and fall of the Staten Island Fresh Kills landfill, how their destinies were entwined from the start, and how the immediate cultural response to the collapse of the former and the closing of the latter recurred to the form of catalogues of objects, words, and images. From this angle it will be possible to posit the events within a larger, if somewhat unusual, cultural frame encompassi...

  18. Double suicide genes selectively kill human umbilical vein endothelial cells

    Directory of Open Access Journals (Sweden)

    Liu Lunxu

    2011-02-01

    Full Text Available Abstract Background To construct a recombinant adenovirus containing CDglyTK double suicide genes and evaluate the killing effect of the double suicide genes driven by kinase domain insert containing receptor (KDR promoter on human umbilical vein endothelial cells. Methods Human KDR promoter, Escherichia coli (E. coli cytosine deaminase (CD gene and the herpes simplex virus-thymidine kinase (TK gene were cloned using polymerase chain reaction (PCR. Plasmid pKDR-CDglyTK was constructed with the KDR promoter and CDglyTK genes. A recombinant adenoviral plasmid AdKDR-CDglyTK was then constructed and transfected into 293 packaging cells to grow and harvest adenoviruses. KDR-expressing human umbilical vein endothelial cells (ECV304 and KDR-negative liver cancer cell line (HepG2 were infected with the recombinant adenoviruses at different multiplicity of infection (MOI. The infection rate was measured by green fluorescent protein (GFP expression. The infected cells were cultured in culture media containing different concentrations of prodrugs ganciclovir (GCV and/or 5-fluorocytosine (5-FC. The killing effects were measured using two different methods, i.e. annexin V-FITC staining and terminal transferase-mediated dUTP nick end-labeling (TUNEL staining. Results Recombinant adenoviruses AdKDR-CDglyTK were successfully constructed and they infected ECV304 and HepG2 cells efficiently. The infection rate was dependent on MOI of recombinant adenoviruses. ECV304 cells infected with AdKDR-CDglyTK were highly sensitive to GCV and 5-FC. The cell survival rate was dependent on both the concentration of the prodrugs and the MOI of recombinant adenoviruses. In contrast, there were no killing effects in the HepG2 cells. The combination of two prodrugs was much more effective in killing ECV304 cells than GCV or 5-FC alone. The growth of transgenic ECV304 cells was suppressed in the presence of prodrugs. Conclusion AdKDR-CDglyTK/double prodrog system may be a useful

  19. Sabretoothed carnivores and the killing of large prey.

    Directory of Open Access Journals (Sweden)

    Ki Andersson

    Full Text Available Sabre-like canines clearly have the potential to inflict grievous wounds leading to massive blood loss and rapid death. Hypotheses concerning sabretooth killing modes include attack to soft parts such as the belly or throat, where biting deep is essential to generate strikes reaching major blood vessels. Sabretoothed carnivorans are widely interpreted as hunters of larger and more powerful prey than that of their present-day nonsabretoothed relatives. However, the precise functional advantage of the sabretooth bite, particularly in relation to prey size, is unknown. Here, we present a new point-to-point bite model and show that, for sabretooths, depth of the killing bite decreases dramatically with increasing prey size. The extended gape of sabretooths only results in considerable increase in bite depth when biting into prey with a radius of less than ∼10 cm. For sabretooths, this size-reversed functional advantage suggests predation on species within a similar size range to those attacked by present-day carnivorans, rather than "megaherbivores" as previously believed. The development of the sabretooth condition appears to represent a shift in function and killing behaviour, rather than one in predator-prey relations. Furthermore, our results demonstrate how sabretoothed carnivorans are likely to have evolved along a functionally continuous trajectory: beginning as an extension of a jaw-powered killing bite, as adopted by present-day pantherine cats, followed by neck-powered biting and thereafter shifting to neck-powered shear-biting. We anticipate this new insight to be a starting point for detailed study of the evolution of pathways that encompass extreme specialisation, for example, understanding how neck-powered biting shifts into shear-biting and its significance for predator-prey interactions. We also expect that our model for point-to-point biting and bite depth estimations will yield new insights into the behaviours of a broad range of

  20. Mercy killing without consent. Historical comments on a controversial issue.

    Science.gov (United States)

    Lauter, H; Meyer, J E

    1982-02-01

    In recent discussions on euthanasia the question about mercy killing without consent of mentally ill persons has turned up, particularly in cases of hopeless suffering among senile or chronically insane patients. Possible analogies to the actions under the German Nazi-regimen and relations to the concept of Social Darwinism with suggestions about active eugenic control as propagated in the early part of this century are outlined in a historical review. The implications and obvious dangers of misuse of any such kind of active euthanasia in psychiatry are discussed on this background.

  1. Fractional Killing-Yano Tensors and Killing Vectors Using the Caputo Derivative in Some One- and Two-Dimensional Curved Space

    Directory of Open Access Journals (Sweden)

    Ehab Malkawi

    2014-01-01

    Full Text Available The classical free Lagrangian admitting a constant of motion, in one- and two-dimensional space, is generalized using the Caputo derivative of fractional calculus. The corresponding metric is obtained and the fractional Christoffel symbols, Killing vectors, and Killing-Yano tensors are derived. Some exact solutions of these quantities are reported.

  2. Emergence of Buprestidae, Cerambycidae, and Scolytinae (Coleoptera) from mountain pine beetle-killed and fire-killed ponderosa pines in the Black Hills, South Dakota, USA

    Science.gov (United States)

    Sheryl L. Costello; William R. Jacobi; Jose F. Negron

    2013-01-01

    Wood borers (Coleoptera: Cerambycidae and Buprestidae) and bark beetles (Coleoptera: Curculionidae) infest ponderosa pines, Pinus ponderosa P. Lawson and C. Lawson, killed by mountain pine beetle (MPB), Dendroctonus ponderosae Hopkins, and fire. No data is available comparing wood borer and bark beetle densities or species guilds associated with MPB-killed or fire-...

  3. Ground Zero/Fresh Kills: Cataloguing Ruins, Garbage, and Memory

    Directory of Open Access Journals (Sweden)

    Cinzia Scarpino

    2011-09-01

    Full Text Available The aim of this paper is to show how the rise and fall of the Twin Towers can be read in relation to the rise and fall of the Staten Island Fresh Kills landfill, how their destinies were entwined from the start, and how the immediate cultural response to the collapse of the former and the closing of the latter recurred to the form of catalogues of objects, words, and images. From this angle it will be possible to posit the events within a larger, if somewhat unusual, cultural frame encompassing the history of two different yet complementary symbols of New York up to 2001 (the WTC and Fresh Kills. From Don DeLillo’s Underworld (1997 and Falling Man (2007 through Holman, Steve Zeitlin e Joe Dobkin’s Crisis (2001-2002; from Art Spiegelman’s In the Shadows of No Tower (2004 to Artists Respond’s 9-11 (2002; from the New York Times to Bearing Witness to History, the 2003-2006 retrospective of the Smithsonian Museum, relevant collective or individual responses to the 2001 attacks took the form of a catalogue, a list, a vertical or horizontal juxtaposition of data, objects, and memories, evoking a suggestive parallel to the organizing principle of past relics collected in museums and garbage stratified in sanitary landfills.

  4. Midgut microbiota and host immunocompetence underlie Bacillus thuringiensis killing mechanism

    Science.gov (United States)

    Caccia, Silvia; Di Lelio, Ilaria; La Storia, Antonietta; Marinelli, Adriana; Varricchio, Paola; Franzetti, Eleonora; Banyuls, Núria; Tettamanti, Gianluca; Casartelli, Morena; Giordana, Barbara; Ferré, Juan; Gigliotti, Silvia; Pennacchio, Francesco

    2016-01-01

    Bacillus thuringiensis is a widely used bacterial entomopathogen producing insecticidal toxins, some of which are expressed in insect-resistant transgenic crops. Surprisingly, the killing mechanism of B. thuringiensis remains controversial. In particular, the importance of the septicemia induced by the host midgut microbiota is still debated as a result of the lack of experimental evidence obtained without drastic manipulation of the midgut and its content. Here this key issue is addressed by RNAi-mediated silencing of an immune gene in a lepidopteran host Spodoptera littoralis, leaving the midgut microbiota unaltered. The resulting cellular immunosuppression was characterized by a reduced nodulation response, which was associated with a significant enhancement of host larvae mortality triggered by B. thuringiensis and a Cry toxin. This was determined by an uncontrolled proliferation of midgut bacteria, after entering the body cavity through toxin-induced epithelial lesions. Consequently, the hemolymphatic microbiota dramatically changed upon treatment with Cry1Ca toxin, showing a remarkable predominance of Serratia and Clostridium species, which switched from asymptomatic gut symbionts to hemocoelic pathogens. These experimental results demonstrate the important contribution of host enteric flora in B. thuringiensis-killing activity and provide a sound foundation for developing new insect control strategies aimed at enhancing the impact of biocontrol agents by reducing the immunocompetence of the host. PMID:27506800

  5. Does host complement kill Borrelia burgdorferi within ticks?

    Science.gov (United States)

    Rathinavelu, Sivaprakash; Broadwater, Anne; de Silva, Aravinda M

    2003-02-01

    The Lyme disease spirochete, Borrelia burgdorferi, inhabits the gut lumen of the tick vector. At this location the spirochete is exposed to host blood when a tick feeds. We report here on studies that were done with normal and complement-deficient (C3-knockout) mice to determine if the host complement system killed spirochetes within the vector. We found that spirochete numbers within feeding nymphs were not influenced by complement, most likely because host complement was inactivated within the vector. The Lyme disease outer surface protein A (OspA) vaccine is a transmission-blocking vaccine that targets spirochetes in the vector. In experiments with mice hyperimmunized with OspA, complement was not required to kill spirochetes within nymphs and to block transmission from nymphs to the vaccinated host. However, host complement did enhance the ability of OspA antibody to block larvae from acquiring spirochetes. Thus, the effects of OspA antibody on nymphal transmission and larval acquisition appear to be based on different mechanisms.

  6. Photoacoustically-guided photothermal killing of mosquitoes targeted by nanoparticles.

    Science.gov (United States)

    Foster, Stephen R; Galanzha, Ekaterina I; Totten, Daniel C; Beneš, Helen; Shmookler Reis, Robert J; Zharov, Vladimir P

    2014-07-01

    In biomedical applications, nanoparticles have demonstrated the potential to eradicate abnormal cells in small localized pathological zones associated with cancer or infections. Here, we introduce a method for nanotechnology-based photothermal (PT) killing of whole organisms considered harmful to humans or the environment. We demonstrate that laser-induced thermal, and accompanying nano- and microbubble phenomena, can injure or kill C. elegans and mosquitoes fed carbon nanotubes, gold nanospheres, gold nanoshells, or magnetic nanoparticles at laser energies that are safe for humans. In addition, a photoacoustic (PA) effect was used to control nanoparticle delivery. Through the integration of this technique with molecular targeting, nanoparticle clustering, magnetic capturing and spectral sharpening of PA and PT plasmonic resonances, our laser-based PA-PT nano-theranostic platform can be applied to detection and the physical destruction of small organisms and carriers of pathogens, such as malaria vectors, spiders, bed bugs, fleas, ants, locusts, grasshoppers, phytophagous mites, or other arthropod pests, irrespective of their resistance to conventional treatments. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Rate-limiting events in hyperthermic cell killing

    International Nuclear Information System (INIS)

    Landry, J.; Marceau, N.

    1978-01-01

    The inactivation rate of HeLa cells for temperatures ranging from 41 to 55 0 C and treatment durations varying from 2 to 300 min was analyzed in thermodynamic terms by considering the dependence of cell free energy (ΔG + ) on temperature. Within this temperature range the loss of proliferative capacity exhibits a complex temperature dependence which is characterized by entropy and enthalpy values that gradually decrease as temperature increases. This complex process of heat-induced cell killing was postulated to be the result of a series of reactions, each of them being alternatively rate limiting within a certain temperature range. From this kinetic scheme a mathematical model was derived and, in the case of HeLa cells, the use of a least-squares search parameter procedure (as applied to the derived survival regression function) demonstrated that three such sequential reactions were sufficient to explain all experimental data points obtained within the 41 to 55 0 C range. The proposed model was also shown to be adequate for explaining survival data of HeLa cells exposed to nanosecond heat pulses of infrared laser energy. Considerations of thermodynamic properties of known biochemical reactions suggest plausible rate-limiting events in hyperthermic cell killing

  8. Identification of Pseudomonas aeruginosa phenazines that kill Caenorhabditis elegans.

    Science.gov (United States)

    Cezairliyan, Brent; Vinayavekhin, Nawaporn; Grenfell-Lee, Daniel; Yuen, Grace J; Saghatelian, Alan; Ausubel, Frederick M

    2013-01-01

    Pathogenic microbes employ a variety of methods to overcome host defenses, including the production and dispersal of molecules that are toxic to their hosts. Pseudomonas aeruginosa, a Gram-negative bacterium, is a pathogen of a diverse variety of hosts including mammals and the nematode Caenorhabditis elegans. In this study, we identify three small molecules in the phenazine class that are produced by P. aeruginosa strain PA14 that are toxic to C. elegans. We demonstrate that 1-hydroxyphenazine, phenazine-1-carboxylic acid, and pyocyanin are capable of killing nematodes in a matter of hours. 1-hydroxyphenazine is toxic over a wide pH range, whereas the toxicities of phenazine-1-carboxylic acid and pyocyanin are pH-dependent at non-overlapping pH ranges. We found that acidification of the growth medium by PA14 activates the toxicity of phenazine-1-carboxylic acid, which is the primary toxic agent towards C. elegans in our assay. Pyocyanin is not toxic under acidic conditions and 1-hydroxyphenazine is produced at concentrations too low to kill C. elegans. These results suggest a role for phenazine-1-carboxylic acid in mammalian pathogenesis because PA14 mutants deficient in phenazine production have been shown to be defective in pathogenesis in mice. More generally, these data demonstrate how diversity within a class of metabolites could affect bacterial toxicity in different environmental niches.

  9. Identification of Pseudomonas aeruginosa phenazines that kill Caenorhabditis elegans.

    Directory of Open Access Journals (Sweden)

    Brent Cezairliyan

    2013-01-01

    Full Text Available Pathogenic microbes employ a variety of methods to overcome host defenses, including the production and dispersal of molecules that are toxic to their hosts. Pseudomonas aeruginosa, a Gram-negative bacterium, is a pathogen of a diverse variety of hosts including mammals and the nematode Caenorhabditis elegans. In this study, we identify three small molecules in the phenazine class that are produced by P. aeruginosa strain PA14 that are toxic to C. elegans. We demonstrate that 1-hydroxyphenazine, phenazine-1-carboxylic acid, and pyocyanin are capable of killing nematodes in a matter of hours. 1-hydroxyphenazine is toxic over a wide pH range, whereas the toxicities of phenazine-1-carboxylic acid and pyocyanin are pH-dependent at non-overlapping pH ranges. We found that acidification of the growth medium by PA14 activates the toxicity of phenazine-1-carboxylic acid, which is the primary toxic agent towards C. elegans in our assay. Pyocyanin is not toxic under acidic conditions and 1-hydroxyphenazine is produced at concentrations too low to kill C. elegans. These results suggest a role for phenazine-1-carboxylic acid in mammalian pathogenesis because PA14 mutants deficient in phenazine production have been shown to be defective in pathogenesis in mice. More generally, these data demonstrate how diversity within a class of metabolites could affect bacterial toxicity in different environmental niches.

  10. Effect of pulsed electron beam on cell killing

    International Nuclear Information System (INIS)

    Acharya, Santhosh; Joseph, Praveen; Sanjeev, Ganesh; Narayana, Y.; Bhat, N.N.

    2009-01-01

    The extent of repairable and irreparable damage in a living cell produced by ionizing radiation depends on the quality of the radiation. In the case of sparsely ionizing radiation, the dose rate and the pattern of energy deposition of the radiation are the important physical factors which can affect the amount of damage in living cells. In the present study, radio-sensitive and radioresistive bacteria cells were exposed to 8 MeV pulsed electron beam and the efficiency of cell-killing was investigated to evaluate the Do, the mean lethal dose. The dose to the cell was delivered in micro-second pulses at an instantaneous dose rate of 2.6 x 10 5 Gy s -1 . Fricke dosimeter was used to measure the absorbed dose of electron beam. The results were compared with those of gamma rays. The survival curve of radio-resistive Deinococcus-radiodurans (DR) is found to be sigmoidal and the survival response for radio-sensitive Escherichia-coli (E-coli) is found to be exponential without any shoulder. Comparison of Do values indicate that irradiation with pulsed electron beam resulted in more cell-killing than was observed for gamma irradiation. (author)

  11. Competition between apex predators? Brown bears decrease wolf kill rate on two continents.

    Science.gov (United States)

    Tallian, Aimee; Ordiz, Andrés; Metz, Matthew C; Milleret, Cyril; Wikenros, Camilla; Smith, Douglas W; Stahler, Daniel R; Kindberg, Jonas; MacNulty, Daniel R; Wabakken, Petter; Swenson, Jon E; Sand, Håkan

    2017-02-08

    Trophic interactions are a fundamental topic in ecology, but we know little about how competition between apex predators affects predation, the mechanism driving top-down forcing in ecosystems. We used long-term datasets from Scandinavia (Europe) and Yellowstone National Park (North America) to evaluate how grey wolf ( Canis lupus ) kill rate was affected by a sympatric apex predator, the brown bear ( Ursus arctos ). We used kill interval (i.e. the number of days between consecutive ungulate kills) as a proxy of kill rate. Although brown bears can monopolize wolf kills, we found no support in either study system for the common assumption that they cause wolves to kill more often. On the contrary, our results showed the opposite effect. In Scandinavia, wolf packs sympatric with brown bears killed less often than allopatric packs during both spring (after bear den emergence) and summer. Similarly, the presence of bears at wolf-killed ungulates was associated with wolves killing less often during summer in Yellowstone. The consistency in results between the two systems suggests that brown bear presence actually reduces wolf kill rate. Our results suggest that the influence of predation on lower trophic levels may depend on the composition of predator communities. © 2017 The Authors.

  12. High levels of mortality, malnutrition, and measles, among recently-displaced Somali refugees in Dagahaley camp, Dadaab refugee camp complex, Kenya, 2011.

    Science.gov (United States)

    Polonsky, Jonathan A; Ronsse, Axelle; Ciglenecki, Iza; Rull, Monica; Porten, Klaudia

    2013-01-22

    Following a rapid influx of over 200,000 displaced Somalis into the Dadaab refugee camp complex in Kenya, Médecins Sans Frontières conducted a mortality and nutrition survey of the population living in Bulo Bacte, a self-settled area surrounding Dagahaley camp (part of this complex). The survey was conducted between 31st July and 10th August 2011. We exhaustively interviewed representatives from all households in Bulo Bacte, collecting information on deaths, births, and population movements during the recall period (15th February 2011 to survey date), in order to provide estimates of retrospective death rates. We recorded the mid-upper arm circumference and presence or absence of bipedal oedema of all children of height 67-global and severe acute malnutrition. The surveyed population included 26,583 individuals, of whom 6,488 (24.4%) were children aged under 5 years. There were 360 deaths reported during the 177 days of the recall period, of which 186 (52%) were among children aged under 5 years. The crude death rate for the entire recall period was 0.8 per 10,000 person-days. The under-5 death rate was 1.8 per 10,000 person-days. More than two-thirds of all deaths were reported to have been associated with diarrhoea (25%), cough or other breathing difficulties (24%), or with fever (19%). Measles accounted for a reported 17% of all deaths; this was due to a measles outbreak that occurred between June and October 2011.Global acute malnutrition was observed in 13.4%, and severe acute malnutrition in 3.0%, of children measuring 67-crisis-affected populations should be revised to take into account the epidemiologic context. Organisations must be sensitive and reactive to changes in the health status of the populations they assist.

  13. Implementasi Prinsip Yurisdiksi Universal Mengenai Pemberantasan Kejahatan Perompakan Laut Di Indonesia

    Directory of Open Access Journals (Sweden)

    Dian Korea

    2018-04-01

    Full Text Available The high seas are all parts of the sea that are not included in the exclusive economic zone, territorial sea, inland waters of a country, or in the archipelagic waters of an archipelago country. Consequently, the case of the interpretation of the case. This happens with the MV Ship. Sinar Kudus is an Indonesian ship that is a jurisdiction of the Indonesian state. For the case, Indonesia is obliged to participate in resolving the piracy case that happened on the MV ship. Sinar Kudus, so the jurisdiction of the Indonesian state against the MV ship. The Holy Light captured by Somali pirates is a passive nationality jurisdiction. In this jurisdictional principle, Indonesia has the right to protect its citizens who are victims of crimes abroad. Constraints in the implementation of Indonesian state jurisdiction over MV Ship. Sinar Kudus which was held hostage by Somali pirates such as MV ship. The holy rays while sailing in international waters were not accompanied by Indonesian warships, so the Indonesian Navy could not directly attack the pirates at the time of piracy. MV Ship. The holy rays are brought to the territorial waters of Somalia by pirates, so what prevails here is the jurisdiction of the Somali state. Seeing the weakness of law enforcement in Somalia makes it difficult for Indonesia to cooperate in the release of the crew of the Sinar Kudus ship held hostage by Somali pirates. Indonesia voted for negotiations on the release of the crew of Sinar Sudus for the safety of crew members being held hostage by Somali pirates.

  14. Lactoferricin Peptides Increase Macrophages' Capacity To Kill Mycobacterium avium.

    Science.gov (United States)

    Silva, Tânia; Moreira, Ana C; Nazmi, Kamran; Moniz, Tânia; Vale, Nuno; Rangel, Maria; Gomes, Paula; Bolscher, Jan G M; Rodrigues, Pedro N; Bastos, Margarida; Gomes, Maria Salomé

    2017-01-01

    Mycobacterial infections cause a significant burden of disease and death worldwide. Their treatment is long, toxic, costly, and increasingly prone to failure due to bacterial resistance to currently available antibiotics. New therapeutic options are thus clearly needed. Antimicrobial peptides represent an important source of new antimicrobial molecules, both for their direct activity and for their immunomodulatory potential. We have previously reported that a short version of the bovine antimicrobial peptide lactoferricin with amino acids 17 to 30 (LFcin17-30), along with its variants obtained by specific amino acid substitutions, killed Mycobacterium avium in broth culture. In the present work, those peptides were tested against M. avium living inside its natural host cell, the macrophage. We found that the peptides increased the antimicrobial action of the conventional antibiotic ethambutol inside macrophages. Moreover, the d-enantiomer of the lactoferricin peptide (d-LFcin17-30) was more stable and induced significant killing of intracellular mycobacteria by itself. Interestingly, d-LFcin17-30 did not localize to M. avium -harboring phagosomes but induced the production of proinflammatory cytokines and increased the formation of lysosomes and autophagosome-like vesicles. These results lead us to conclude that d-LFcin17-30 primes macrophages for intracellular microbial digestion through phagosomal maturation and/or autophagy, culminating in mycobacterial killing. IMPORTANCE The genus Mycobacterium comprises several pathogenic species, including M. tuberculosis , M. leprae , M. avium , etc. Infections caused by these bacteria are particularly difficult to treat due to their intrinsic impermeability, low growth rate, and intracellular localization. Antimicrobial peptides are increasingly acknowledged as potential treatment tools, as they have a high spectrum of activity, low tendency to induce bacterial resistance, and immunomodulatory properties. In this study, we

  15. Opinions of university students on honour killings: Perspective from Islamabad and Rawalpindi.

    Science.gov (United States)

    Shaikh, Masood Ali; Kamal, Anila; Naqvi, Irum

    2015-04-01

    Honour killing incidents have been reported from every province of Pakistan. In 2014 a pregnant woman was killed in front of Lahore High Court, by her family members, in the name of honour. This study was conducted to determine the perspective of university students on honour killing with specific reference to one such killing incident in Lahore. Cumulatively, 989 students participated in the survey. Compared with female students, male students were less likely to agree and were more unequivocal that a woman has a right to marry any man she wants despite her family's disapproval, in a statistically significant manner. Similarly, male students were statistically significantly more likely to report that killing in the name of honour is always justified and were less equivocal about it compared to female students. Nonetheless, cumulatively 824 (83.3%) students believed that killing in the name of honour is not always justified.

  16. Efficient Kill-Save Ratios Ease Up the Cognitive Demands on Counterintuitive Moral Utilitarianism.

    Science.gov (United States)

    Trémolière, Bastien; Bonnefon, Jean-François

    2014-07-01

    The dual-process model of moral judgment postulates that utilitarian responses to moral dilemmas (e.g., accepting to kill one to save five) are demanding of cognitive resources. Here we show that utilitarian responses can become effortless, even when they involve to kill someone, as long as the kill-save ratio is efficient (e.g., 1 is killed to save 500). In Experiment 1, participants responded to moral dilemmas featuring different kill-save ratios under high or low cognitive load. In Experiments 2 and 3, participants responded at their own pace or under time pressure. Efficient kill-save ratios promoted utilitarian responding and neutered the effect of load or time pressure. We discuss whether this effect is more easily explained by a parallel-activation model or by a default-interventionist model. © 2014 by the Society for Personality and Social Psychology, Inc.

  17. DNA-repair, cell killing and normal tissue damage

    International Nuclear Information System (INIS)

    Dahm-Daphi, J.; Dikomey, E.; Brammer, I.

    1998-01-01

    Background: Side effects of radiotherapy in normal tissue is determined by a variety of factors of which cellular and genetic contributions are described here. Material and methods: Review. Results: Normal tissue damage after irradiation is largely due to loss of cellular proliferative capacity. This can be due to mitotic cell death, apoptosis, or terminal differentiation. Dead or differentiated cells release cytokines which additionally modulate the tissue response. DNA damage, in particular non-reparable or misrepaired double-strand breaks are considered the basic lesion leading to G1-arrest and ultimately to cell inactivation. Conclusion: Evidence for genetic bases of normal tissue response, cell killing and DNA-repair capacity is presented. However, a direct link of all 3 endpoints has not yet been proved directly. (orig.) [de

  18. Medicolegal investigation of political killings in El Salvador.

    Science.gov (United States)

    Thomsen, J L; Gruschow, J; Stover, E

    1989-06-17

    An axiom of Thomas Hobbes states that "people are never more helpless than when the force meant to protect their rights turns against them." Hobbes' axiom holds true today, with Amnesty International reporting that hundreds of thousands have been murdered by their governments. This article examines the medicolegal aspects of an investigation into the deaths of two Salvadoran peasants who were reportedly tortured and executed by soldiers in February 1988. One of the authors, Thomsen, participated in the investigation as a court-ordered expert, and as a representative of the American Association for the Advancement of Science and of a Salvadoran legal aid organization. His necropsy findings are reported with observations and comments. The article concludes with suggestions for initiatives that might be undertaken by individual physicians and institutions to improve the quality and impartiality of medicolegal investigations into political killings.

  19. Invariant Killing spinors in 11D and type II supergravities

    International Nuclear Information System (INIS)

    Gran, U; Gutowski, J; Papadopoulos, G

    2009-01-01

    We present all isotropy groups and associated Σ groups, up to discrete identifications of the component connected to the identity, of spinors of 11-dimensional and type II supergravities. The Σ groups are products of a Spin group and an R-symmetry group of a suitable lower dimensional supergravity theory. Using the case of SU(4)-invariant spinors as a paradigm, we demonstrate that the Σ groups, and so the R-symmetry groups of lower dimensional supergravity theories arising from compactifications, have disconnected components. These lead us to discrete symmetry groups reminiscent of R-parity. We examine the role of disconnected components of the Σ groups in the choice of Killing spinor representatives and in the context of compactifications.

  20. Fish Kill Incidents and Harmful Algal Blooms in Omani Waters

    Directory of Open Access Journals (Sweden)

    Hamed Mohammed Al Gheilani

    2011-01-01

    Full Text Available Red tide, one of the harmful algal blooms (HABs is a natural ecological phenomenon and often this event is accompanied by severe impacts on coastal resources, local economies, and public health. The occurrence of red tides has become more frequent in Omani waters in recent years. Some of them caused fish kill, damaged fishery resources and mariculture, threatened the marine environment and the osmosis membranes of desalination plants. However, a number of them have been harmless. The most common dinoflagellate Noctiluca scintillans is associated with the red tide events in Omani waters. Toxic species like Karenia selliformis, Prorocentrum arabianum, and Trichodesmium erythraeum have also been reported recently. Although red tides in Oman have been considered a consequence of upwelling in the summer season (May to September, recent phytoplankton outbreaks in Oman are not restricted to summer. Frequent algal blooms have been reported during winter (December to March. HABs may have contributed to hypoxia and/or other negative ecological impacts.

  1. Terrorism as Genocide: Killing with “Intent”

    Directory of Open Access Journals (Sweden)

    Ashlie Perry

    2012-07-01

    Full Text Available It is plausible that terrorism can manifest itself as a form of genocide. Using Raphael Lemkin’s definition of genocide and the UN Genocide Convention’s definition of genocide, non-state and state terrorism are assessed as a form of genocide. Commonalities found in the definitions of both genocide and terrorism supports the argument. The psychology of terrorism and Lemkin’s psychology of genocide describe similar motivations of perpetrators. The September 11th attacks and the U.S. invasion of Iraq are used as case studies to illustrate that terrorism can result in genocide or genocidal acts. Framing acts of terrorism as genocide allows for prosecution in international courts and brings a new perspective to the concept of killing with intent.

  2. Necessity, private defence and the killing of Mary.

    Science.gov (United States)

    Rogers, J

    2001-07-01

    This article examines the reasons used by the Court of Appeal in Re A (Children) to authorise and justify an operation which would inevitably kill the weaker of a pair of conjoined twins in order to offer the stronger twin a good chance of a long and happy life. The crux of the judgment was that a utilitarian theory of necessity could justify this operation. This article seeks to define the criminal law defences at issue in the case and to argue that utilitarian necessity is such a dangerous doctrine that it should never be employed if there is any other defence which can be made to serve the same purpose--as there was in the present case.

  3. Beyond Democratic Tolerance: Witch Killings in Timor-Leste

    Directory of Open Access Journals (Sweden)

    Rebecca Strating

    2015-01-01

    Full Text Available Newly democratising states experience challenges in reconciling “traditional” or “customary” dispute resolution practices with newly established state-based legal systems based on the rule of law. For Timor-Leste, these tensions are pronounced in continuing debates concerning the killing or injuring of women accused of witchcraft. Defences of extrajudicial punishments tend to conflate democracy with local support and fail to deal with the key institutions of democratic systems, including the rule of law, political equality, and civil rights. In Timor-Leste’s case, where equality and social rights were incorporated into the Constitution as fundamental governmental obligations, localised extrajudicial punishments threaten internal and external state legitimacy and highlight the difficulties of ensuring the primacy of state-based institutions. Extrajudicial punishments challenge Timor-Leste’s capacity to consolidate new liberal democratic political institutions.

  4. Age and sex composition of seals killed by polar bears in the eastern Beaufort Sea.

    Directory of Open Access Journals (Sweden)

    Nicholas W Pilfold

    Full Text Available Polar bears (Ursus maritimus of the Beaufort Sea enter hyperphagia in spring and gain fat reserves to survive periods of low prey availability. We collected information on seals killed by polar bears (n=650 and hunting attempts on ringed seal (Pusa hispida lairs (n=1396 observed from a helicopter during polar bear mark-recapture studies in the eastern Beaufort Sea in spring in 1985-2011. We investigated how temporal shifts in ringed seal reproduction affect kill composition and the intraspecific vulnerabilities of ringed seals to polar bear predation.Polar bears primarily preyed on ringed seals (90.2% while bearded seals (Erignathus barbatus only comprised 9.8% of the kills, but 33% of the biomass. Adults comprised 43.6% (150/344 of the ringed seals killed, while their pups comprised 38.4% (132/344. Juvenile ringed seals were killed at the lowest proportion, comprising 18.0% (62/344 of the ringed seal kills. The proportion of ringed seal pups was highest between 2007-2011, in association with high ringed seal productivity. Half of the adult ringed seal kills were ≥ 21 years (60/121, and kill rates of adults increased following the peak of parturition. Determination of sex from DNA revealed that polar bears killed adult male and adult female ringed seals equally (0.50, n=78. The number of hunting attempts at ringed seal subnivean lair sites was positively correlated with the number of pup kills (r(2 =0.30, P=0.04, but was not correlated with the number of adult kills (P=0.37.Results are consistent with decadal trends in ringed seal productivity, with low numbers of pups killed by polar bears in spring in years of low pup productivity, and conversely when pup productivity was high. Vulnerability of adult ringed seals to predation increased in relation to reproductive activities and age, but not gender.

  5. Break the Kill Chain, Not the Budget: How to Avoid U.S. Strategic Retrenchment

    Science.gov (United States)

    2016-06-10

    mass quantities. The United States maintained a Cold War offset strategy focused on technology and kill chain annihilation with an understanding of...Annihilating the kill chain with advanced instruments of war is more the norm than the exception in the post- Cold War era U.S. military. The U.S. Air...Masters Thesis 3. DATES COVERED (From - To) 27-07-2015 to 10-06-2016 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER BREAK THE KILL CHAIN

  6. How Effective Is Road Mitigation at Reducing Road-Kill? A Meta-Analysis

    OpenAIRE

    Rytwinski, Trina; Soanes, Kylie; Jaeger, Jochen A. G.; Fahrig, Lenore; Findlay, C. Scott; Houlahan, Jeff; van der Ree, Rodney; van der Grift, Edgar A

    2016-01-01

    Road traffic kills hundreds of millions of animals every year, posing a critical threat to the populations of many species. To address this problem there are more than forty types of road mitigation measures available that aim to reduce wildlife mortality on roads (road-kill). For road planners, deciding on what mitigation method to use has been problematic because there is little good information about the relative effectiveness of these measures in reducing road-kill, and the costs of these...

  7. Multiple factors and processes involved in host cell killing by bacteriophage Mu: characterization and mapping.

    Science.gov (United States)

    Waggoner, B T; Marrs, C F; Howe, M M; Pato, M L

    1984-07-15

    The regions of bacteriophage Mu involved in host cell killing were determined by infection of a lambda-immune host with 12 lambda pMu-transducing phages carrying different amounts of Mu DNA beginning at the left end. Infecting lambda pMu phages containing 5.0 (+/- 0.2) kb or less of the left end of Mu DNA did not kill the lambda-immune host, whereas lambda pMu containing 5.1 kb did kill, thus locating the right end of the kil gene between approximately 5.0 and 5.1 kb. For the Kil+ phages the extent of killing increased as the multiplicity of infection (m.o.i.) increased. In addition, killing was also affected by the presence of at least two other regions of Mu DNA: one, located between 5.1 and 5.8 kb, decreased the extent of killing; the other, located between 6.3 and 7.9 kb, greatly increased host cell killing. Killing was also assayed after lambda pMu infection of a lambda-immune host carrying a mini-Mu deleted for most of the B gene and the middle region of Mu DNA. Complementation of mini-Mu replication by infecting B+ lambda pMu phages resulted in killing of the lambda-immune, mini-Mu-containing host, regardless of the presence or absence of the Mu kil gene. The extent of host cell killing increased as the m.o.i. of the infecting lambda pMu increased, and was further enhanced by both the presence of the kil gene and the region located between 6.3 and 7.9 kb. These distinct processes of kil-mediated killing in the absence of replication and non-kil-mediated killing in the presence of replication were also observed after induction of replication-deficient and kil mutant prophages, respectively.

  8. An Analysis Of Intrinsic Elements In Harper Lee’s To Kill A Mockingbird

    OpenAIRE

    Simbolon, Hendra Halomoan

    2011-01-01

    Skripsi ini berjudul “An Analysis of Intrinsic Elements in Harper Lee’s To Kill A Mockingbird”. Skripsi ini mengenai unsur-unsur intrinsik yakni karakter, plot, setting, tema, sudut pandang dan gaya penulisan yang terdapat pada karya Charles Dickens yang berjudul To Kill A Mockingbird. Di dalam skripsi ini, penulis ingin membuktikan keterkaitan unsur-unsur intrinsik yang terdapat dalam novel To Kill A Mockingbird karya Harper Lee. Adapun metode yang digunakan penul...

  9. Experiment for dose measurement during beam killing at Indus-1 synchrotron radiation source

    International Nuclear Information System (INIS)

    Nayak, M.K.; Dev, Vipin; Haridas, G.; Thakkar, K.K.; Sarkar, P.K.; Sharma, D.N.

    2006-01-01

    Experimental measurement of radiation dose likely to be received by an occupational worker in the experimental hall of Indus-1 during accidental beam killing was carried out. Various accidental beam-killing scenarios were experimentally simulated for the measurement. The measurement was carried out using direct reading dosimeters. Result shows that in the event of accidental beam killing, dose likely to be received by an occupational worker outside the shield is negligible. (author)

  10. The number of killings in southern rural Norway, 1300–1569

    OpenAIRE

    Kadane, Joseph B.; Næshagen, Ferdinand L.

    2013-01-01

    Three dual systems estimates are employed to study the number of killings in southern rural Norway in a period of slightly over 250 years. The first system is a set of five letters sent to each killer as part of the legal process. The second system is the mention of killings from all other contemporary sources. The posterior distributions derived suggest fewer such killings than rough demographic estimates.

  11. Age and sex composition of seals killed by polar bears in the eastern Beaufort Sea.

    Science.gov (United States)

    Pilfold, Nicholas W; Derocher, Andrew E; Stirling, Ian; Richardson, Evan; Andriashek, Dennis

    2012-01-01

    Polar bears (Ursus maritimus) of the Beaufort Sea enter hyperphagia in spring and gain fat reserves to survive periods of low prey availability. We collected information on seals killed by polar bears (n=650) and hunting attempts on ringed seal (Pusa hispida) lairs (n=1396) observed from a helicopter during polar bear mark-recapture studies in the eastern Beaufort Sea in spring in 1985-2011. We investigated how temporal shifts in ringed seal reproduction affect kill composition and the intraspecific vulnerabilities of ringed seals to polar bear predation. Polar bears primarily preyed on ringed seals (90.2%) while bearded seals (Erignathus barbatus) only comprised 9.8% of the kills, but 33% of the biomass. Adults comprised 43.6% (150/344) of the ringed seals killed, while their pups comprised 38.4% (132/344). Juvenile ringed seals were killed at the lowest proportion, comprising 18.0% (62/344) of the ringed seal kills. The proportion of ringed seal pups was highest between 2007-2011, in association with high ringed seal productivity. Half of the adult ringed seal kills were ≥ 21 years (60/121), and kill rates of adults increased following the peak of parturition. Determination of sex from DNA revealed that polar bears killed adult male and adult female ringed seals equally (0.50, n=78). The number of hunting attempts at ringed seal subnivean lair sites was positively correlated with the number of pup kills (r(2) =0.30, P=0.04), but was not correlated with the number of adult kills (P=0.37). Results are consistent with decadal trends in ringed seal productivity, with low numbers of pups killed by polar bears in spring in years of low pup productivity, and conversely when pup productivity was high. Vulnerability of adult ringed seals to predation increased in relation to reproductive activities and age, but not gender.

  12. An evaluation of sex-age-kill (SAK) model performance

    Science.gov (United States)

    Millspaugh, Joshua J.; Skalski, John R.; Townsend, Richard L.; Diefenbach, Duane R.; Boyce, Mark S.; Hansen, Lonnie P.; Kammermeyer, Kent

    2009-01-01

    The sex-age-kill (SAK) model is widely used to estimate abundance of harvested large mammals, including white-tailed deer (Odocoileus virginianus). Despite a long history of use, few formal evaluations of SAK performance exist. We investigated how violations of the stable age distribution and stationary population assumption, changes to male or female harvest, stochastic effects (i.e., random fluctuations in recruitment and survival), and sampling efforts influenced SAK estimation. When the simulated population had a stable age distribution and λ > 1, the SAK model underestimated abundance. Conversely, when λ < 1, the SAK overestimated abundance. When changes to male harvest were introduced, SAK estimates were opposite the true population trend. In contrast, SAK estimates were robust to changes in female harvest rates. Stochastic effects caused SAK estimates to fluctuate about their equilibrium abundance, but the effect dampened as the size of the surveyed population increased. When we considered both stochastic effects and sampling error at a deer management unit scale the resultant abundance estimates were within ±121.9% of the true population level 95% of the time. These combined results demonstrate extreme sensitivity to model violations and scale of analysis. Without changes to model formulation, the SAK model will be biased when λ ≠ 1. Furthermore, any factor that alters the male harvest rate, such as changes to regulations or changes in hunter attitudes, will bias population estimates. Sex-age-kill estimates may be precise at large spatial scales, such as the state level, but less so at the individual management unit level. Alternative models, such as statistical age-at-harvest models, which require similar data types, might allow for more robust, broad-scale demographic assessments.

  13. Bystander Host Cell Killing Effects of Clostridium perfringens Enterotoxin

    Directory of Open Access Journals (Sweden)

    Archana Shrestha

    2016-12-01

    Full Text Available Clostridium perfringens enterotoxin (CPE binds to claudin receptors, e.g., claudin-4, and then forms a pore that triggers cell death. Pure cultures of host cells that do not express claudin receptors, e.g., fibroblasts, are unaffected by pathophysiologically relevant CPE concentrations in vitro. However, both CPE-insensitive and CPE-sensitive host cells are present in vivo. Therefore, this study tested whether CPE treatment might affect fibroblasts when cocultured with CPE-sensitive claudin-4 fibroblast transfectants or Caco-2 cells. Under these conditions, immunofluorescence microscopy detected increased death of fibroblasts. This cytotoxic effect involved release of a toxic factor from the dying CPE-sensitive cells, since it could be reproduced using culture supernatants from CPE-treated sensitive cells. Supernatants from CPE-treated sensitive cells, particularly Caco-2 cells, were found to contain high levels of membrane vesicles, often containing a CPE species. However, most cytotoxic activity remained in those supernatants even after membrane vesicle depletion, and CPE was not detected in fibroblasts treated with supernatants from CPE-treated sensitive cells. Instead, characterization studies suggest that a major cytotoxic factor present in supernatants from CPE-treated sensitive cells may be a 10- to 30-kDa host serine protease or require the action of that host serine protease. Induction of caspase-3-mediated apoptosis was found to be important for triggering release of the cytotoxic factor(s from CPE-treated sensitive host cells. Furthermore, the cytotoxic factor(s in these supernatants was shown to induce a caspase-3-mediated killing of fibroblasts. This bystander killing effect due to release of cytotoxic factors from CPE-treated sensitive cells could contribute to CPE-mediated disease.

  14. Melanoma stem cells in experimental melanoma are killed by radioimmunotherapy

    International Nuclear Information System (INIS)

    Jandl, Thomas; Revskaya, Ekaterina; Jiang, Zewei; Harris, Matthew; Dorokhova, Olena; Tsukrov, Dina; Casadevall, Arturo; Dadachova, Ekaterina

    2013-01-01

    Introduction: In spite of recently approved B-RAF inhibitors and immunomodulating antibodies, metastatic melanoma has poor prognosis and novel treatments are needed. Melanoma stem cells (MSC) have been implicated in the resistance of this tumor to chemotherapy. Recently we demonstrated in a Phase I clinical trial in patients with metastatic melanoma that radioimmunotherapy (RIT) with 188-Rhenium( 188 Re)-6D2 antibody to melanin was a safe and effective modality. Here we investigated the interaction of MSC with RIT as a possible mechanism for RIT efficacy. Methods: Mice bearing A2058 melanoma xenografts were treated with either 1.5 mCi 188 Re-6D2 antibody, saline, unlabeled 6D2 antibody or 188 Re-labeled non-specific IgM. Results: On Day 28 post-treatment the tumor size in the RIT group was 4-times less than in controls (P < 0.001). The tumors were analyzed by immunohistochemistry and FACS for two MSC markers — chemoresistance mediator ABCB5 and H3K4 demethylase JARID1B. There were no significant differences between RIT and control groups in percentage of ABCB5 or JARID1B-positive cells in the tumor population. Our results demonstrate that unlike chemotherapy, which kills tumor cells but leaves behind MSC leading to recurrence, RIT kills MSC at the same rate as the rest of tumor cells. Conclusions: These results have two main implications for melanoma treatment and possibly other cancers. First, the susceptibility of ABCB5 + and JARID1B + cells to RIT in melanoma might be indicative of their susceptibility to antibody-targeted radiation in other cancers where they are present as well. Second, specifically targeting cancer stem cells with radiolabeled antibodies to ABCB5 or JARID1B might help to completely eradicate cancer stem cells in various cancers

  15. Potentiation of radiation-induced cell kill by synthetic metalloporphyrins

    International Nuclear Information System (INIS)

    O'Hara, J.A.; Douple, E.B.; Abrams, M.J.; Picker, D.J.; Giandomenico, C.M.; Vollano, J.F.

    1989-01-01

    The effects of the combination of several meso-substituted, water soluble metalloporphyrins with ionizing radiation on hypoxic and oxic monolayers of Chinese hamster fibroblast (V79N) cells were studied. The metalloporphyrins tested included a series of cationic metalloporphyrins complexed with Co(III), Zn(II), Fe(III), Cu(II), Pd(II) or Mn(III) and a series of anionic porphyrins chelated with Co(III), Fe(III), Cu(II), Rh(III), Mn(III) or Sn(IV). Both cationic and anionic free porphyrins were also tested. Cationic ligands were tetrakis(4N-methylpyridyl)porphine [TMPyP], tetrakis(4N-trimethylamino phenyl)porphine [TMAP], tetrakis(4N-butylpyridyl)porphine [TBPyP] and tetrakis(3N-methylpyridyl)porphine [3TMPyP]. Anionic ligands tested were tetrakis(4-sulfonato phenyl)porphine [TPPS], tetrakis(biphenyl)porphine sulfonate [TBPS] and tetrakis(4-carboxyphenyl)porphine [TCPP]. SER calculated from survival curves and SFR from one radiation dose were used to assess the relative effectiveness of this class as non-cytotoxic hypoxic and oxic cell-kill potentiators. Comparisons were made at 100 microM, which was essentially non-toxic (greater than 70% survival) for all porphyrins tested except for Co[TMPyP] (approximately 50% survival after 1 hour at 37 degrees C under oxic conditions). The greatest effects on radiation-induced cell kill were achieved with Co[TPPS] and Co[TMPyP] with SER values of 2.3 and 2.4 respectively. Porphyrin analogs with no coordinated metal were found to be less active than the same compound with metal. The overall charge on the molecule did not systematically relate to the biological activity of the compounds tested

  16. Male killing Spiroplasma protects Drosophila melanogaster against two parasitoid wasps

    Science.gov (United States)

    Xie, J; Butler, S; Sanchez, G; Mateos, M

    2014-01-01

    Maternally transmitted associations between endosymbiotic bacteria and insects are diverse and widespread in nature. Owing to imperfect vertical transmission, many heritable microbes have evolved compensational mechanisms to enhance their persistence in host lineages, such as manipulating host reproduction and conferring fitness benefits to host. Symbiont-mediated defense against natural enemies of hosts is increasingly recognized as an important mechanism by which endosymbionts enhance host fitness. Members of the genus Spiroplasma associated with distantly related Drosophila hosts are known to engage in either reproductive parasitism (i.e., male killing) or defense against natural enemies (the parasitic wasp Leptopilina heterotoma and a nematode). A male-killing strain of Spiroplasma (strain Melanogaster Sex Ratio Organism (MSRO)) co-occurs with Wolbachia (strain wMel) in certain wild populations of the model organism Drosophila melanogaster. We examined the effects of Spiroplasma MSRO and Wolbachia wMel on Drosophila survival against parasitism by two common wasps, Leptopilina heterotoma and Leptopilina boulardi, that differ in their host ranges and host evasion strategies. The results indicate that Spiroplasma MSRO prevents successful development of both wasps, and confers a small, albeit significant, increase in larva-to-adult survival of flies subjected to wasp attacks. We modeled the conditions under which defense can contribute to Spiroplasma persistence. Wolbachia also confers a weak, but significant, survival advantage to flies attacked by L. heterotoma. The host protective effects exhibited by Spiroplasma and Wolbachia are additive and may provide the conditions for such cotransmitted symbionts to become mutualists. Occurrence of Spiroplasma-mediated protection against distinct parasitoids in divergent Drosophila hosts suggests a general protection mechanism. PMID:24281548

  17. To Kill, Stay or Flee: The Effects of Lions and Landscape Factors on Habitat and Kill Site Selection of Cheetahs in South Africa

    OpenAIRE

    Rostro-Garc?a, Susana; Kamler, Jan F.; Hunter, Luke T. B.

    2015-01-01

    Understanding how animals utilize available space is important for their conservation, as it provides insight into the ecological needs of the species, including those related to habitat, prey and inter and intraspecific interactions. We used 28 months of radio telemetry data and information from 200 kill locations to assess habitat selection at the 3rd order (selection of habitats within home ranges) and 4th order (selection of kill sites within the habitats used) of a reintroduced populatio...

  18. Carbon stocks of trees killed by bark beetles and wildfire in the western United States

    International Nuclear Information System (INIS)

    Hicke, Jeffrey A; Meddens, Arjan J H; Kolden, Crystal A; Allen, Craig D

    2013-01-01

    Forests are major components of the carbon cycle, and disturbances are important influences of forest carbon. Our objective was to contribute to the understanding of forest carbon cycling by quantifying the amount of carbon in trees killed by two disturbance types, fires and bark beetles, in the western United States in recent decades. We combined existing spatial data sets of forest biomass, burn severity, and beetle-caused tree mortality to estimate the amount of aboveground and belowground carbon in killed trees across the region. We found that during 1984–2010, fires killed trees that contained 5–11 Tg C year −1 and during 1997–2010, beetles killed trees that contained 2–24 Tg C year −1 , with more trees killed since 2000 than in earlier periods. Over their periods of record, amounts of carbon in trees killed by fires and by beetle outbreaks were similar, and together these disturbances killed trees representing 9% of the total tree carbon in western forests, a similar amount to harvesting. Fires killed more trees in lower-elevation forest types such as Douglas-fir than higher-elevation forest types, whereas bark beetle outbreaks also killed trees in higher-elevation forest types such as lodgepole pine and Engelmann spruce. Over 15% of the carbon in lodgepole pine and spruce/fir forest types was in trees killed by beetle outbreaks; other forest types had 5–10% of the carbon in killed trees. Our results document the importance of these natural disturbances in the carbon budget of the western United States. (letter)

  19. Effects of Vegetation Structure on the Location of Lion Kill Sites in African Thicket.

    Directory of Open Access Journals (Sweden)

    Andrew B Davies

    Full Text Available Predator-prey relationships are integral to ecosystem stability and functioning. These relationships are, however, difficult to maintain in protected areas where large predators are increasingly being reintroduced and confined. Where predators make kills has a profound influence on their role in ecosystems, but the relative importance of environmental variables in determining kill sites, and how these might vary across ecosystems is poorly known. We investigated kill sites for lions in South Africa's thicket biome, testing the importance of vegetation structure for kill site locations compared to other environmental variables. Kill sites were located over four years using GPS telemetry and compared to non-kill sites that had been occupied by lions, as well as to random sites within lion ranges. Measurements of 3D vegetation structure obtained from Light Detection and Ranging (LiDAR were used to calculate the visible area (viewshed around each site and, along with wind and moonlight data, used to compare kill sites between lion sexes, prey species and prey sexes. Viewshed area was the most important predictor of kill sites (sites in dense vegetation were twice as likely to be kill sites compared to open areas, followed by wind speed and, less so, moonlight. Kill sites for different prey species varied with vegetation structure, and male prey were killed when wind speeds were higher compared to female prey of the same species. Our results demonstrate that vegetation structure is an important component of predator-prey interactions, with varying effects across ecosystems. Such differences require consideration in terms of the ecological roles performed by predators, and in predator and prey conservation.

  20. Effects of Vegetation Structure on the Location of Lion Kill Sites in African Thicket.

    Science.gov (United States)

    Davies, Andrew B; Tambling, Craig J; Kerley, Graham I H; Asner, Gregory P

    2016-01-01

    Predator-prey relationships are integral to ecosystem stability and functioning. These relationships are, however, difficult to maintain in protected areas where large predators are increasingly being reintroduced and confined. Where predators make kills has a profound influence on their role in ecosystems, but the relative importance of environmental variables in determining kill sites, and how these might vary across ecosystems is poorly known. We investigated kill sites for lions in South Africa's thicket biome, testing the importance of vegetation structure for kill site locations compared to other environmental variables. Kill sites were located over four years using GPS telemetry and compared to non-kill sites that had been occupied by lions, as well as to random sites within lion ranges. Measurements of 3D vegetation structure obtained from Light Detection and Ranging (LiDAR) were used to calculate the visible area (viewshed) around each site and, along with wind and moonlight data, used to compare kill sites between lion sexes, prey species and prey sexes. Viewshed area was the most important predictor of kill sites (sites in dense vegetation were twice as likely to be kill sites compared to open areas), followed by wind speed and, less so, moonlight. Kill sites for different prey species varied with vegetation structure, and male prey were killed when wind speeds were higher compared to female prey of the same species. Our results demonstrate that vegetation structure is an important component of predator-prey interactions, with varying effects across ecosystems. Such differences require consideration in terms of the ecological roles performed by predators, and in predator and prey conservation.

  1. Patterns and Composition of Road-Killed Wildlife in Northwest Argentina

    Science.gov (United States)

    Cuyckens, Griet An Erica; Mochi, Lucía Sol; Vallejos, María; Perovic, Pablo Gastón; Biganzoli, Fernando

    2016-11-01

    Roads have important effects on wildlife, such as natural habitat fragmentation and degradation and direct killing of fauna, which leads to reductions in wildlife population size. We focused on a principal road in Northwest Argentina to test for the effect of seasonality and landscape features on the composition of road-killed wildlife. We conducted regularly scheduled road trips during the dry and wet seasons. We recorded the presence or absence of a vegetation curtain or hedge along the road. We measured land use by remote sensing in a 500 m buffer along the road. We compared the abundance of animals killed between seasons (dry and wet) for different taxonomic groups (mammals, birds and reptiles) and for different origins (domestic and native). We built linear mixed models to test the effect of landscape features on the abundance of killed animals. Two hundred and ninety-three individuals were killed, belonging to 35 species; 75.8 % were native and 24.2 % domestic species. The majority of animals killed were mid-sized mammals. More animals were killed during the dry season. The most important factors to explain the wildlife road-killing were the season and the proportion of agricultural landscape. The composition of the killed animals changed with the season. The proportion of agricultural landscape incremented the number of killed birds and mammals during both seasons, without affecting reptiles. The ratio of wild to domestic animals killed was dependent on the season. This study sets a precedent as the first in road ecology in Northwest Argentina and should be taken into account for road planning and regulation.

  2. Knowledge translation in Africa for 21st century integrative biology: the "know-do gap" in family planning with contraceptive use among Somali women.

    Science.gov (United States)

    Ahmed, Ahmed A; Mohamed, Abdullahi A; Guled, Ibrahim A; Elamin, Hayfa M; Abou-Zeid, Alaa H

    2014-11-01

    An emerging dimension of 21(st) century integrative biology is knowledge translation in global health. The maternal mortality rate in Somalia is amongst the highest in the world. We set out to study the "know-do" gap in family planning measures in Somalia, with a view to inform future interventions for knowledge integration between theory and practice. We interviewed 360 Somali females of reproductive age and compared university-educated females to women with less or no education, using structured interviews, with a validated questionnaire. The mean age of marriage was 18 years, with 4.5 pregnancies per marriage. The mean for the desired family size was 9.3 and 10.5 children for the university-educated group and the less-educated group, respectively. Importantly, nearly 90% of the university-educated group knew about family planning, compared to 45.6% of the less-educated group. All of the less-educated group indicated that they would never use contraceptives, as compared to 43.5% of the university-educated group. Prevalence of contraceptive use among ever-married women was 4.3%. In the less-educated group, 80.6% indicated that they would not recommend contraceptives to other women as compared to 66.0% of the university-educated group. There is a huge gap between knowledge and practice regarding family planning in Somalia. The attendant reasons for this gap, such as level of education, expressed personal religious beliefs and others, are examined here. For primary health care to gain traction in Africa, we need to address the existing "know-do" gaps that are endemic and adversely impacting on global health. This is the first independent research study examining the knowledge gaps for family planning in Somalia in the last 20 years, with a view to understanding knowledge integration in a global world. The results shall guide policy makers, donors, and implementers to develop a sound family planning policy and program to improve maternal and child health in 21(st

  3. Experiencing 'pathologized presence and normalized absence'; understanding health related experiences and access to health care among Iraqi and Somali asylum seekers, refugees and persons without legal status.

    Science.gov (United States)

    Fang, Mei Lan; Sixsmith, Judith; Lawthom, Rebecca; Mountian, Ilana; Shahrin, Afifa

    2015-09-19

    Asylum seekers, refugees and persons without legal status have been reported to experience a range of difficulties when accessing public services and supports in the UK. While research has identified health care barriers to equitable access such as language difficulties, it has not considered the broader social contexts of marginalization experienced through the dynamics of 'othering'. The current study explores health and health care experiences of Somali and Iraqi asylum seekers, refugees and persons without legal status, highlighting 'minoritization' processes and the 'pathologization' of difference as analytical lenses to understand the multiple layers of oppression that contribute to health inequities. For the study, qualitative methods were used to document the lived experiences of asylum seekers, refugees and persons without legal status. Thirty-five in-depth interviews and five focus groups were used to explore personal accounts, reveal shared understandings and enable social, cognitive and emotional understandings of on-going health problems and challenges when seeking treatment and care. A participatory framework was undertaken which inspired collaborative workings with local organizations that worked directly with asylum seekers, refugees and persons without legal status. The analysis revealed four key themes: 1) pre-departure histories and post-arrival challenges; 2) legal status; 3) health knowledges and procedural barriers as well as 4) language and cultural competence. Confidentiality, trust, wait times and short doctor-patient consultations were emphasized as being insufficient for culturally specific communications and often translating into inadequate treatment and care. Barriers to accessing health care was associated with social disadvantage and restrictions of the broader welfare system suggesting that a re-evaluation of the asylum seeking process is required to improve the situation. Macro- and micro-level intersections of accustomed societal

  4. Access to HIV Care and Resilience in a Long-Term Conflict Setting: A Qualitative Assessment of the Experiences of Living with Diagnosed HIV in Mogadishu, Somali.

    Science.gov (United States)

    Kulane, Asli; Owuor, John O A; Sematimba, Douglas; Abdulahi, Sacdia Abdisamad; Yusuf, Hamdi Moalim; Mohamed, Lul M

    2017-07-05

    Human Immunodeficiency Virus (HIV) continues to take a heavy toll on the lives of many people, with the worst impact on health and wellbeing for the affected individuals in fragile states. The HIV situation in Somalia is not clearly known and experiences of the people living with HIV in this war-torn region are often unexpressed. This pilot qualitative study sought to explore the experiences of people diagnosed with HIV living in Mogadishu, and their resilience in access to care and social support. Participants were recruited through drug dispensers at the HIV clinic in Banadir Hospital. Face-to-face in-depth interviews were conducted in Somali in May 2013 among patients who were receiving antiretroviral therapy (ART) from the HIV clinic in Mogadishu. These were tape-recorded, transcribed, and translated for content analysis. Three women and four men who were living with HIV shared the following narratives. Their perception was that they had either got HIV from their spouses or through health care contamination. They were very knowledgeable about the realities of HIV, how the medication works, nutritional requirements, and drug adherence. They were always willing to go an extra mile to secure a good life for themselves. However, the external HIV stigma impacted their access to care. They faced challenges in their homes and at work which compelled them to seek support from non-governmental organizations (NGOs) or close family members. This stigma often affected their disclosure to the wider community due to the uncertainty of the repercussions, leading to a life of extreme loneliness and financial difficulties. The participants' coping mechanisms included living together and starting their own NGO for support with very strong optimism about their prognosis. The people diagnosed with HIV living in Mogadishu are highly knowledgeable about HIV transmission, the realities of living with a diagnosed HIV infection, and the efficacy of HIV treatment. Our small sample

  5. Access to HIV Care and Resilience in a Long-Term Conflict Setting: A Qualitative Assessment of the Experiences of Living with Diagnosed HIV in Mogadishu, Somali

    Science.gov (United States)

    Kulane, Asli; Owuor, John O. A.; Abdulahi, Sacdia Abdisamad; Yusuf, Hamdi Moalim; Mohamed, Lul M.

    2017-01-01

    Background: Human Immunodeficiency Virus (HIV) continues to take a heavy toll on the lives of many people, with the worst impact on health and wellbeing for the affected individuals in fragile states. The HIV situation in Somalia is not clearly known and experiences of the people living with HIV in this war-torn region are often unexpressed. This pilot qualitative study sought to explore the experiences of people diagnosed with HIV living in Mogadishu, and their resilience in access to care and social support. Methods: Participants were recruited through drug dispensers at the HIV clinic in Banadir Hospital. Face-to-face in-depth interviews were conducted in Somali in May 2013 among patients who were receiving antiretroviral therapy (ART) from the HIV clinic in Mogadishu. These were tape-recorded, transcribed, and translated for content analysis. Results: Three women and four men who were living with HIV shared the following narratives. Their perception was that they had either got HIV from their spouses or through health care contamination. They were very knowledgeable about the realities of HIV, how the medication works, nutritional requirements, and drug adherence. They were always willing to go an extra mile to secure a good life for themselves. However, the external HIV stigma impacted their access to care. They faced challenges in their homes and at work which compelled them to seek support from non-governmental organizations (NGOs) or close family members. This stigma often affected their disclosure to the wider community due to the uncertainty of the repercussions, leading to a life of extreme loneliness and financial difficulties. The participants’ coping mechanisms included living together and starting their own NGO for support with very strong optimism about their prognosis. Conclusions: The people diagnosed with HIV living in Mogadishu are highly knowledgeable about HIV transmission, the realities of living with a diagnosed HIV infection, and the

  6. Peptidoglycan recognition proteins kill bacteria by inducing oxidative, thiol, and metal stress.

    Directory of Open Access Journals (Sweden)

    Des Raj Kashyap

    2014-07-01

    Full Text Available Mammalian Peptidoglycan Recognition Proteins (PGRPs are a family of evolutionary conserved bactericidal innate immunity proteins, but the mechanism through which they kill bacteria is unclear. We previously proposed that PGRPs are bactericidal due to induction of reactive oxygen species (ROS, a mechanism of killing that was also postulated, and later refuted, for several bactericidal antibiotics. Here, using whole genome expression arrays, qRT-PCR, and biochemical tests we show that in both Escherichia coli and Bacillus subtilis PGRPs induce a transcriptomic signature characteristic of oxidative stress, as well as correlated biochemical changes. However, induction of ROS was required, but not sufficient for PGRP killing. PGRPs also induced depletion of intracellular thiols and increased cytosolic concentrations of zinc and copper, as evidenced by transcriptome changes and supported by direct measurements. Depletion of thiols and elevated concentrations of metals were also required, but by themselves not sufficient, for bacterial killing. Chemical treatment studies demonstrated that efficient bacterial killing can be recapitulated only by the simultaneous addition of agents leading to production of ROS, depletion of thiols, and elevation of intracellular metal concentrations. These results identify a novel mechanism of bacterial killing by innate immunity proteins, which depends on synergistic effect of oxidative, thiol, and metal stress and differs from bacterial killing by antibiotics. These results offer potential targets for developing new antibacterial agents that would kill antibiotic-resistant bacteria.

  7. Quantification of dichlorvos released from kill strips used in boll weevil eradication programs

    Science.gov (United States)

    Two types of kill strips, Hercon Vaportape II and Plato Insecticide Strip, are used by boll weevil, Anthonomus grandis (Boheman), eradication programs in the U.S. Both types utilize dichlorvos as the killing agent and are marketed to last up to a month in traps. Consequently, programs typically re...

  8. 9 CFR 113.202 - Canine Hepatitis and Canine Adenovirus Type 2 Vaccine, Killed Virus.

    Science.gov (United States)

    2010-01-01

    ... Type 2 Vaccine, Killed Virus. 113.202 Section 113.202 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Killed Virus Vaccines § 113.202 Canine Hepatitis and Canine...

  9. 9 CFR 113.207 - Encephalomyelitis Vaccine, Eastern, Western, and Venezuelan, Killed Virus.

    Science.gov (United States)

    2010-01-01

    ..., Western, and Venezuelan, Killed Virus. 113.207 Section 113.207 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Killed Virus Vaccines § 113.207 Encephalomyelitis...

  10. Habitat or matrix: which is more relevant to predict road-kill of vertebrates?

    Science.gov (United States)

    Bueno, C; Sousa, C O M; Freitas, S R

    2015-11-01

    We believe that in tropics we need a community approach to evaluate road impacts on wildlife, and thus, suggest mitigation measures for groups of species instead a focal-species approach. Understanding which landscape characteristics indicate road-kill events may also provide models that can be applied in other regions. We intend to evaluate if habitat or matrix is more relevant to predict road-kill events for a group of species. Our hypothesis is: more permeable matrix is the most relevant factor to explain road-kill events. To test this hypothesis, we chose vertebrates as the studied assemblage and a highway crossing in an Atlantic Forest region in southeastern Brazil as the study site. Logistic regression models were designed using presence/absence of road-kill events as dependent variables and landscape characteristics as independent variables, which were selected by Akaike's Information Criterion. We considered a set of candidate models containing four types of simple regression models: Habitat effect model; Matrix types effect models; Highway effect model; and, Reference models (intercept and buffer distance). Almost three hundred road-kills and 70 species were recorded. River proximity and herbaceous vegetation cover, both matrix effect models, were associated to most road-killed vertebrate groups. Matrix was more relevant than habitat to predict road-kill of vertebrates. The association between river proximity and road-kill indicates that rivers may be a preferential route for most species. We discuss multi-species mitigation measures and implications to movement ecology and conservation strategies.

  11. How effective is road mitigation at reducing road-kill? A meta-analysis

    NARCIS (Netherlands)

    Rytwinski, Trina; Soanes, Kylie; Jaeger, Jochen A.G.; Fahrig, Lenore; Findlay, C.S.; Houlahan, Jeff; Ree, van der Rodney; Grift, van der Edgar A.

    2016-01-01

    Road traffic kills hundreds of millions of animals every year, posing a critical threat to the populations of many species. To address this problem there are more than forty types of road mitigation measures available that aim to reduce wildlife mortality on roads (road-kill). For road planners,

  12. Comparing Road-Kill Datasets from Hunters and Citizen Scientists in a Landscape Context

    Directory of Open Access Journals (Sweden)

    Florian Heigl

    2016-10-01

    Full Text Available Road traffic has severe effects on animals, especially when road-kills are involved. In many countries, official road-kill data are provided by hunters or police; there are also road-kill observations reported by citizen scientists. The aim of the current study was to test whether road-kill reports by hunters stem from similar landscapes than those reported by citizen scientists. We analysed the surrounding landscapes of 712 road-kill reportings of European hares in the province of Lower Austria. Our data showed that road-killed hares reported both by hunters and citizens are predominantly surrounded by arable land. No difference of hedges and solitary trees could be found between the two datasets. However, significant differences in landcover classes and surrounding road networks indicate that hunters’ and citizen scientists’ data are different. Hunters reported hares from landscapes with significantly higher percentages of arable land, and greater lengths of secondary roads. In contrast, citizens reported hares from landscapes with significantly higher percentages of urban or industrial areas and greater lengths of motorways, primary roads, and residential roads. From this we argue that hunters tend to report data mainly from their hunting areas, whereas citizens report data during their daily routine on the way to/from work. We conclude that a citizen science approach is an important source for road-kill data when used in addition to official data with the aim of obtaining an overview of road-kill events on a landscape scale.

  13. A New Calculation Method of Dynamic Kill Fluid Density Variation during Deep Water Drilling

    Directory of Open Access Journals (Sweden)

    Honghai Fan

    2017-01-01

    Full Text Available There are plenty of uncertainties and enormous challenges in deep water drilling due to complicated shallow flow and deep strata of high temperature and pressure. This paper investigates density of dynamic kill fluid and optimum density during the kill operation process in which dynamic kill process can be divided into two stages, that is, dynamic stable stage and static stable stage. The dynamic kill fluid consists of a single liquid phase and different solid phases. In addition, liquid phase is a mixture of water and oil. Therefore, a new method in calculating the temperature and pressure field of deep water wellbore is proposed. The paper calculates the changing trend of kill fluid density under different temperature and pressure by means of superposition method, nonlinear regression, and segment processing technique. By employing the improved model of kill fluid density, deep water kill operation in a well is investigated. By comparison, the calculated density results are in line with the field data. The model proposed in this paper proves to be satisfactory in optimizing dynamic kill operations to ensure the safety in deep water.

  14. Using DNA to describe and quantify interspecific killing of fishers in California

    Science.gov (United States)

    Greta M. Wengert; Mourad W. Gabriel; Sean M. Matthews; J. Mark Higley; Rick A. Sweitzer; Craig. M. Thompson; Kathryn L. Purcell; Reginald H. Barrett; Leslie W. Woods; Rebecca E. Green; Stefan M. Keller; Patricia M. Gaffney; Megan Jones; Benjamin N. Sacks

    2014-01-01

    Interspecific killing is common among carnivores and can have population-level effects on imperiled species. The fisher (Pekania [Martes] pennant) is a rare forest carnivore in western North America and a candidate for listing under the United States Endangered Species Act. Interspecific killing and...

  15. Mothers Who Kill Their Offspring: Testing Evolutionary Hypothesis in a 110-Case Italian Sample

    Science.gov (United States)

    Camperio Ciani, Andrea S.; Fontanesi, Lilybeth

    2012-01-01

    Objectives: This research aimed to identify incidents of mothers in Italy killing their own children and to test an adaptive evolutionary hypothesis to explain their occurrence. Methods: 110 cases of mothers killing 123 of their own offspring from 1976 to 2010 were analyzed. Each case was classified using 13 dichotomic variables. Descriptive…

  16. ANALYSIS OF MATERIALS IN AN EXPERIMENTAL TESTING PIPE SYSTEM FOR AN INHIBITOR OF MUSSEL KILL

    Energy Technology Data Exchange (ETDEWEB)

    Daniel P. Molloy

    2003-06-04

    A comprehensive series of 16 laboratory experiments demonstrated that the presence of vinyl tubing within a recirculating pipe system was responsible for lowering zebra mussel kill following treatment with the bacterium Pseudomonas fluorescens. All vinyl tubing was replaced in all testing units with silicone tubing, and high mussel kill (>95%) was then obtained.

  17. Comparison of two mathematical models for describing heat-induced cell killing

    International Nuclear Information System (INIS)

    Roti Roti, J.L.; Henle, K.J.

    1980-01-01

    A computer-based minimization algorithm is utilized to obtain the optimum fits of two models to hyperthermic cell killing data. The models chosen are the multitarget, single-hit equation, which is in general use, and the linear-quadratic equation, which has been applied to cell killing by ionizing irradiation but not to heat-induced cell killing. The linear-quadratic equation fits hyperthermic cell killing data as well as the multitarget, single-hit equation. Both parameters of the linear-quadratic equation obey the Arrhenius law, whereas only one of the two parameters of the multitarget, single-hit equation obeys the Arrhenius law. Thus the linear-quadratic function can completely define cell killing as a function of both time and temperature. In addition, the linear-quadratic model will provide a simplified approach to the study of the synergism between heat and X irradiation

  18. NH125 kills methicillin-resistant Staphylococcus aureus persisters by lipid bilayer disruption.

    Science.gov (United States)

    Kim, Wooseong; Fricke, Nico; Conery, Annie L; Fuchs, Beth Burgwyn; Rajamuthiah, Rajmohan; Jayamani, Elamparithi; Vlahovska, Petia M; Ausubel, Frederick M; Mylonakis, Eleftherios

    2016-01-01

    NH125, a known WalK inhibitor kills MRSA persisters. However, its precise mode of action is still unknown. The mode of action of NH125 was investigated by comparing its spectrum of antimicrobial activity and its effects on membrane permeability and giant unilamellar vesicles (GUVs) with walrycin B, a WalR inhibitor and benzyldimethylhexadecylammonium chloride (16-BAC), a cationic surfactant. NH125 killed persister cells of a variety of Staphylococcus aureus strains. Similar to 16-BAC, NH125 killed MRSA persisters by inducing rapid membrane permeabilization and caused the rupture of GUVs, whereas walrycin B did not kill MRSA persisters or induce membrane permeabilization and did not affect GUVs. NH125 kills MRSA persisters by interacting with and disrupting membranes in a detergent-like manner.

  19. Rapid kill-novel endodontic sealer and Enterococcus faecalis.

    Directory of Open Access Journals (Sweden)

    Nurit Beyth

    Full Text Available With growing concern over bacterial resistance, the identification of new antimicrobial means is paramount. In the oral cavity microorganisms are essential to the development of periradicular diseases and are the major causative factors associated with endodontic treatment failure. As quaternary ammonium compounds have the ability to kill a wide array of bacteria through electrostatic interactions with multiple anionic targets on the bacterial surface, it is likely that they can overcome bacterial resistance. Melding these ideas, we investigated the potency of a novel endodontic sealer in limiting Enterococcus faecalis growth. We used a polyethyleneimine scaffold to synthesize nano-sized particles, optimized for incorporation into an epoxy-based endodontic sealer. The novel endodontic sealer was tested for its antimicrobial efficacy and evaluated for biocompatibility and physical eligibility. Our results show that the novel sealer foundation affixes the nanoparticles, achieving surface bactericidal properties, but at the same time impeding nanoparticle penetration into eukaryotic cells and thereby mitigating a possible toxic effect. Moreover, adequate physical properties are maintained. The nanosized quaternary amine particles interact within minutes with bacteria, triggering cell death across wide pH values. Throughout this study we demonstrate a new antibacterial perspective for endodontic sealers; a novel antibacterial, effective and safe antimicrobial means.

  20. Targeted Anticancer Immunotoxins and Cytotoxic Agents with Direct Killing Moieties

    Directory of Open Access Journals (Sweden)

    Koji Kawakami

    2006-01-01

    Full Text Available Despite the progress of the bioinformatics approach to characterize cell-surface antigens and receptors on tumor cells, it remains difficult to generate novel cancer vaccines or neutralizing monoclonal antibody therapeutics. Among targeted cancer therapeutics, biologicals with targetable antibodies or ligands conjugated or fused to toxins or chemicals for direct cell-killing ability have been developed over the last 2 decades. These conjugated or fused chimeric proteins are termed immunotoxins or cytotoxic agents. Two agents, DAB389IL-2 (ONTAKTM targeting the interleukin-2 receptor and CD33-calicheamicin (Mylotarg®, have been approved by the FDA for cutaneous T-cell lymphoma (CTCL and relapsed acute myeloid leukemia (AML, respectively. Such targetable agents, including RFB4(dsFv-PE38 (BL22, IL13-PE38QQR, and Tf-CRM107, are being tested in clinical trials. Several agents using unique technology such as a cleavable adapter or immunoliposomes with antibodies are also in the preclinical stage. This review summarizes the generation, mechanism, and development of these agents. In addition, possible future directions of this therapeutic approach are discussed.

  1. Killing mediated spatial structure in V. Cholerae biofilms

    Science.gov (United States)

    Yanni, David

    Most bacteria live in biofilms, which are implicated in 60 - 80 % of microbial infections in the body. The spatial structure of a biofilm confers advantages to its member-cells, such as antibiotic resistance, and is strongly affected by competition between strains and taxa. However, A complete picture of how competition affects the self-organized structure of these complex, far-from-equilibrium systems, is yet to emerge. To that end, we investigate phase separation dynamics driven by T6SS-facilitated bacterial warfare in a system composed of two strains of mutually antagonistic V. cholerae. T6SS is a contact mediated killing mechanism present in 25 % of all gram negative bacteria, and has been shown by recent work to play a major role in the spatial assortment of biofilms. T6SS events induce lysis, causing variations in local mechanical pressure, and acting as thermalizing events. We study cells immobilized in biofilms at the air-solid interface, so our experimental system represents a different type active matter, wherein activity is due to cell death and reproduction, not mobility. Here, we show how that activity imposes a constraint of minimal curvature on strain-strain interfaces; an effective Laplace pressure is characterized which governs interfacial dynamics.

  2. Resistance to and killing by the sporicidal microbicide peracetic acid.

    Science.gov (United States)

    Leggett, Mark J; Schwarz, J Spencer; Burke, Peter A; Mcdonnell, Gerald; Denyer, Stephen P; Maillard, Jean-Yves

    2015-03-01

    To elucidate the mechanisms of spore resistance to and killing by the oxidizing microbicide peracetic acid (PAA). Mutants of Bacillus subtilis lacking specific spore structures were used to identify resistance properties in spores and to understand the mechanism of action of PAA. We also assessed the effect of PAA treatment on a number of spore properties including heat tolerance, membrane integrity and germination. The spore coat is essential for spore PAA resistance as spores with defective coats were greatly sensitized to PAA treatment. Small acid-soluble spore proteins apparently provide no protection against PAA. Defects in spore germination, specifically in germination via the GerB and GerK but not the GerA germination receptors, as well as leakage of internal components suggest that PAA is active at the spore inner membrane. It is therefore likely that the inner membrane is the major site of PAA's sporicidal activity. PAA treatment targets the spore membrane, with some of its activity directed specifically against the GerB and GerK germination receptors. © The Author 2014. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  3. Filicide: mental illness in those who kill their children.

    Science.gov (United States)

    Flynn, Sandra M; Shaw, Jenny J; Abel, Kathryn M

    2013-01-01

    Most child victims of homicide are killed by a parent or step-parent. This large population study provides a contemporary and detailed description of filicide perpetrators. We examined the relationship between filicide and mental illness at the time of the offence, and care received from mental health services in the past. All filicide and filicide-suicide cases in England and Wales (1997-2006) were drawn from a national index of homicide perpetrators. Data on people in contact with mental health services were obtained via a questionnaire from mental health teams. Additional clinical information was collected from psychiatric reports. 6144 people were convicted of homicide, 297 were filicides, and 45 cases were filicide-suicides. 195 (66%) perpetrators were fathers. Mothers were more likely than fathers to have a history of mental disorder (66% v 27%) and symptoms at the time of the offence (53% v 23%), most often affective disorder. 17% of mothers had schizophrenia or other delusional disorders. Overall 8% had schizophrenia. 37% were mentally ill at the time of the offence. 20% had previously been in contact with mental health services, 12% within a year of the offence. In the majority of cases, mental illness was not a feature of filicide. However, young mothers and parents with severe mental illness, especially affective and personality disorder who are providing care for children, require careful monitoring by mental health and other support services. Identifying risk factors for filicide requires further research.

  4. Filicide: mental illness in those who kill their children.

    Directory of Open Access Journals (Sweden)

    Sandra M Flynn

    Full Text Available Most child victims of homicide are killed by a parent or step-parent. This large population study provides a contemporary and detailed description of filicide perpetrators. We examined the relationship between filicide and mental illness at the time of the offence, and care received from mental health services in the past.All filicide and filicide-suicide cases in England and Wales (1997-2006 were drawn from a national index of homicide perpetrators. Data on people in contact with mental health services were obtained via a questionnaire from mental health teams. Additional clinical information was collected from psychiatric reports.6144 people were convicted of homicide, 297 were filicides, and 45 cases were filicide-suicides. 195 (66% perpetrators were fathers. Mothers were more likely than fathers to have a history of mental disorder (66% v 27% and symptoms at the time of the offence (53% v 23%, most often affective disorder. 17% of mothers had schizophrenia or other delusional disorders. Overall 8% had schizophrenia. 37% were mentally ill at the time of the offence. 20% had previously been in contact with mental health services, 12% within a year of the offence.In the majority of cases, mental illness was not a feature of filicide. However, young mothers and parents with severe mental illness, especially affective and personality disorder who are providing care for children, require careful monitoring by mental health and other support services. Identifying risk factors for filicide requires further research.

  5. Book review: Mosquito eradication: The story of killing Campto

    Science.gov (United States)

    Lapointe, Dennis

    2015-01-01

    In 1826, the paradise that was the Hawaiian Islands was changed forever when the first mosquito species was accidentally introduced to the island of Maui. Though it has not lived up to its potential as a vector of human disease in the islands, Culex quinquefasciatus and the avian pathogens it transmits laid waste to perhaps the world's most remarkable insular avifauna. Today the lowland native forests, once deafening with birdsong, are largely devoid of native birds and Cx. quinquefasciatus has become an inextricable part of our natural areas. In the Hawaiian Islands, the conservation community struggles to keep invasive species out and to control a number of species that have become naturalized. Despite the millions of dollars spent, these efforts never seem enough to slow the erosion of our native biota. The restoration and long-term preservation of Hawaiian forest birds depend on the nearly complete control of mosquito-borne avian disease, an obstacle that to many land managers appears insurmountable. To rally hope in Hawai`i, the conservation community needs to see a success. As a Pacific island, Hawai`i shares similar conservation problems with New Zealand and has often looked to that nation for innovation and inspiration. Mosquito Eradication: The Story of Killing Campto may be our latest inspiration.

  6. Homicide in the Canadian Prairies: elderly and nonelderly killings.

    Science.gov (United States)

    Ahmed, A G; Menzies, Robin P D

    2002-11-01

    To examine the psychosocial and clinical characteristics of male perpetrators of elderly and nonelderly homicides in the Canadian Prairies. We examined data drawn from a study of 901 adult homicide offenders who were incarcerated or on parole between 1988 and 1992 in Alberta, Saskatchewan, and Manitoba. Of those studied, 67 men were convicted of homicide involving 79 elderly victims, and 671 were convicted of homicide involving 675 nonelderly victims. Most perpetrators were single and engaged in irregular patterns of employment at the time of their index offence. Fourteen (20.8%) offenders with elderly victims had a history of psychiatric treatment, compared with 98 (14.6%) offenders with nonelderly victims; however, this difference was not statistically significant. Approximately 30% of both groups were diagnosed with personality disorders. A comparison of the index- offence characteristics showed no significant differences between the 2 groups. Our findings suggest that elderly individuals are more likely to be killed in their own homes by strangers. Social isolation appears to be a significant risk factor in cases of elderly homicide.

  7. Infective endocarditis and phlebotomies may have killed mozart.

    Science.gov (United States)

    Lee, Simon Jong-Koo

    2010-12-01

    Thirty-five year-old Amadeus Mozart died in Vienna after an acute illness that lasted only 15 days but no consensus has been reached on the cause of his death. From many letters written by his farther it is almost certain that he experienced at least three episodes of acute rheumatic fever attack in his childhood, and a relapse of rheumatic fever was suggested to have killed Mozart, although death from acute rheumatic fever is very rare in adults. His last illness was characterized by high fever, massive edema, vomiting and skin rash. His last illness can be explained by infectious endocarditis and heart failure. During his last hours, he was given phlebotomy, possibly for the third time in two weeks, and soon after he became unconscious and died. As such, phlebotomy performed on a man dehydrated by high fever and vomiting may have caused systemic shock. In summary, Mozart probably died from chronic rheumatic heart disease complicated by infective endocarditis and heart failure, and repeated phlebotomy-induced hypovolemic shock.

  8. Epirubicin-adsorbed nanodiamonds kill chemoresistant hepatic cancer stem cells.

    Science.gov (United States)

    Wang, Xin; Low, Xinyi Casuarine; Hou, Weixin; Abdullah, Lissa Nurrul; Toh, Tan Boon; Mohd Abdul Rashid, Masturah; Ho, Dean; Chow, Edward Kai-Hua

    2014-12-23

    Chemoresistance is a primary cause of treatment failure in cancer and a common property of tumor-initiating cancer stem cells. Overcoming mechanisms of chemoresistance, particularly in cancer stem cells, can markedly enhance cancer therapy and prevent recurrence and metastasis. This study demonstrates that the delivery of Epirubicin by nanodiamonds is a highly effective nanomedicine-based approach to overcoming chemoresistance in hepatic cancer stem cells. The potent physical adsorption of Epirubicin to nanodiamonds creates a rapidly synthesized and stable nanodiamond-drug complex that promotes endocytic uptake and enhanced tumor cell retention. These attributes mediate the effective killing of both cancer stem cells and noncancer stem cells in vitro and in vivo. Enhanced treatment of both tumor cell populations results in an improved impairment of secondary tumor formation in vivo compared with treatment by unmodified chemotherapeutics. On the basis of these results, nanodiamond-mediated drug delivery may serve as a powerful method for overcoming chemoresistance in cancer stem cells and markedly improving overall treatment against hepatic cancers.

  9. Axisymmetric Electrovacuum Spacetimes with AN Additional Killing Vector and Radiation

    Science.gov (United States)

    Pravdová, A.; Bičák, J.

    2002-12-01

    In the present note we briefly summarize our recent work [1, 2] on possible additional symmetries of axially symmetric electrovacuum spacetimes which admit radiation. The main result states that only boost and rotation (axially) symmetric electrovacuum spacetimes can be radiative and asymptotically flat at null infinity {J} which admits global sections. If an additional symmetry is a translational spacelike or null Killing field the spacetime represents cylindrical or plane-type waves, local {J} may still exist but some of its generators are missing. Boost-rotation symmetric spacetimes are the only known exact explicit radiative solutions of Einstein's equations describing moving objects - singularities or black holes uniformly accelerated along the axis of symmetry. They are radiative and admit a smooth {J} although at least four points of {J} are missing. They represent the only known examples in which arbitrarily strong initial data with the given symmetry can be chosen on a hyperboloidal hypersurface which evolve into a complete, smooth null infinity and regular timelike infinity. For the latest reviews, containing a number of relevant references, see [3, 4]...

  10. Comparisons of boll weevil (Coleoptera: Curculionidae) pheromone traps with and without kill strips.

    Science.gov (United States)

    Suh, C P C; Armstrong, J S; Spurgeon, D W; Duke, S

    2009-02-01

    Boll weevil, Anthonomus grandis grandis Boheman (Coleoptera: Curculionidae), eradication programs typically equip pheromone traps with an insecticide-impregnated kill strip. These strips are intended to kill captured insects, thereby simplifying trap servicing and reducing the loss of weevils from predation and escape. However, the effectiveness of kill strips has not been extensively evaluated. We examined the influences of kill strips on weevil captures, trap servicing, and the incidences of weevil predation and trap obstruction (e.g., by spider webs). Evaluations were conducted weekly during three different production periods (pre- to early-, late-, and postseason) of cotton, Gossypium hirsutum L., to represent different environmental conditions and weevil population levels. Within each period, mean weekly captures of weevils in traps with and without kill strips were statistically similar. On average, traps with kill strips took 9 s longer to service than traps without kill strips, but statistical differences were only detected during the late-season period. Overall, the mean weekly proportion of traps with evidence of weevil predation or trap obstruction was significantly lower for traps with kill strips (0.25) than for traps without kill strips (0.37). However, this reduction in the frequency of weevil predation or trap obstruction was too small to produce a corresponding increase in the numbers of weevils captured. In light of these findings, the use of kill strips is likely unnecessary in eradication programs, but may be a consideration in situations when the numbers of deployed traps are reduced and chronic problems with weevil predation or trap obstruction exist.

  11. Welfare Risks of Repeated Application of On-Farm Killing Methods for Poultry

    Directory of Open Access Journals (Sweden)

    Jessica E. Martin

    2018-03-01

    Full Text Available Council Regulation (EC no. 1099/2009 on the protection of animals at the time of killing restricts the use of manual cervical dislocation in poultry on farms in the European Union (EU to birds weighing up to 3 kg and 70 birds per person per day. However, few studies have examined whether repeated application of manual cervical dislocation has welfare implications and whether these are dependent on individual operator skill or susceptibility to fatigue. We investigated the effects of repeated application (100 birds at a fixed killing rate of 1 bird per 2 min and multiple operators on two methods of killing of broilers, laying hens, and turkeys in commercial settings. We compared the efficacy and welfare impact of repeated application of cervical dislocation and a percussive killer (Cash Poultry Killer, CPK, using 12 male stockworkers on three farms (one farm per bird type. Both methods achieved over 96% kill success at the first attempt. The killing methods were equally effective for each bird type and there was no evidence of reduced performance with time and/or bird number. Both methods of killing caused a rapid loss of reflexes, indicating loss of brain function. There was more variation in reflex durations and post-mortem damage in birds killed by cervical dislocation than that found using CPK. High neck dislocation was associated with improved kill success and more rapid loss of reflexes. The CPK caused damage to multiple brain areas with little variation. Overall, the CPK was associated with faster abolition of reflexes, with fewer birds exhibiting them at all, suggestive of better welfare outcomes. However, technical difficulties with the CPK highlighted the advantages of cervical dislocation, which can be performed immediately with no equipment. At the killing rates tested, we did not find evidence to justify the current EU limit on the number of birds that one operator can kill on–farm by manual cervical dislocation.

  12. Reptile road-kills in Southern Brazil: Composition, hot moments and hotspots.

    Science.gov (United States)

    Gonçalves, Larissa Oliveira; Alvares, Diego Janisch; Teixeira, Fernanda Zimmermann; Schuck, Gabriela; Coelho, Igor Pfeifer; Esperandio, Isadora Beraldi; Anza, Juan; Beduschi, Júlia; Bastazini, Vinicius Augusto Galvão; Kindel, Andreas

    2018-02-15

    Understanding road-kill patterns is the first step to assess the potential effects of road mortality on wildlife populations, as well as to define the need for mitigation and support its planning. Reptiles are one of the vertebrate groups most affected by roads through vehicle collisions, both because they are intentionally killed by drivers, and due to their biological needs, such as thermoregulation, which make them more prone to collisions. We conducted monthly road surveys (33months), searching for carcasses of freshwater turtles, lizards, and snakes on a 277-km stretch of BR-101 road in Southernmost Brazil to estimate road-kill composition and magnitude and to describe the main periods and locations of road-kills. We modeled the distribution of road-kills in space according to land cover classes and local traffic volume. Considering the detection capacity of our method and carcass persistence probability, we estimated that 15,377 reptiles are road-killed per year (55reptiles/km/year). Road-kills, especially lizards and snakes, were concentrated during summer, probably due to their higher activity in this period. Road-kill hotspots were coincident among freshwater turtles, lizards, and snakes. Road-kill distribution was negatively related to pine plantations, and positively related to rice plantations and traffic volume. A cost-benefit analysis highlighted that if mitigation measures were installed at road-kill hotspots, which correspond to 21% of the road, they could have avoided up to 45% of recorded reptile fatalities, assuming a 100% mitigation effectiveness. Given the congruent patterns found for all three taxa, the same mitigation measures could be used to minimize the impacts of collision on local herpetofauna. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Liming Poultry Manures to Kill Pathogens and Decrease Soluble Phosphorus

    International Nuclear Information System (INIS)

    Maguire, R.; Hesterberg, D.; Gernat, A.; Anderson, K.; Wineland, M.; Grimes, J.

    2006-01-01

    Received for publication September 9, 2005. Stabilizing phosphorus (P) in poultry waste to reduce P losses from manured soils is important to protect surface waters, while pathogens in manures are an emerging issue. This study was conducted to evaluate CaO and Ca(OH) 2 for killing manure bacterial populations (pathogens) and stabilizing P in poultry wastes and to investigate the influence on soils following amendment with the treated wastes. Layer manure and broiler litter varying in moisture content were treated with CaO and Ca(OH) 2 at rates of 2.5, 5, 10, and 15% by weight. All treated wastes were analyzed for microbial plate counts, pH, and water-soluble phosphorus (WSP), while a few selected layer manures were analyzed by phosphorus X-ray absorption near edge structure (XANES). A loamy sand and a silt loam were amended with broiler litter and layer manure treated with CaO at rates of 0, 2.5, 5, 10, and 15% and soil WSP and pH were measured at times 1, 8, and 29 d. Liming reduced bacterial populations, with greater rates of lime leading to greater reductions; for example 10% CaO applied to 20% solids broiler litter reduced the plate counts from 793 000 to 6500 mL -1 . Liming also reduced the WSP in the manures by over 90% in all cases where at least 10% CaO was added. Liming the manures also reduced WSP in soils immediately following application and raised soil pH. The liming process used successfully reduced plate counts and concerns about P losses in runoff following land application of these limed products due to decreased WSP

  14. Investigation of hot ductility in Al-killed boron steels

    International Nuclear Information System (INIS)

    Chown, L.H.; Cornish, L.A.

    2008-01-01

    The influence of boron to nitrogen ratio, strain rate and cooling rate on hot ductility of aluminium-killed, low carbon, boron microalloyed steel was investigated. Hot tensile testing was performed on steel samples reheated in argon to 1300 deg. C, cooled at rates of 0.3, 1.2 and 3.0 deg. C s -1 to temperatures in the range 750-1050 deg. C, and then strained to failure at initial strain rates of 1 x 10 -4 or 1 x 10 -3 s -1 . It was found that the steel with a B:N ratio of 0.19 showed deep hot ductility troughs for all tested conditions; the steel with a B:N ratio of 0.47 showed a deep ductility trough for a high cooling rate of 3.0 deg. C s -1 and the steel with a near-stoichiometric B:N ratio of 0.75 showed no ductility troughs for the tested conditions. The ductility troughs extended from ∼900 deg. C (near the Ae 3 temperature) to ∼1000 or 1050 deg. C in the single-phase austenite region. The proposed mechanism of hot ductility improvement with increase in B:N ratio in these steels is that the B removes N from solution, thus reducing the strain-induced precipitation of AlN. Additionally, BN co-precipitates with sulphides, preventing precipitation of fine MnS, CuS and FeS, and forming large, complex precipitates that have no effect on hot ductility

  15. Antimicrobial Photodynamic Therapy to Kill Gram-negative Bacteria

    Science.gov (United States)

    Sperandio, Felipe F; Huang, Ying-Ying; Hamblin, Michael R

    2013-01-01

    Antimicrobial photodynamic therapy (PDT) or photodynamic inactivation (PDI) is a new promising strategy to eradicate pathogenic microorganisms such as Gram-positive and Gram-negative bacteria, yeasts and fungi. The search for new approaches that can kill bacteria but do not induce the appearance of undesired drug-resistant strains suggests that PDT may have advantages over traditional antibiotic therapy. PDT is a non-thermal photochemical reaction that involves the simultaneous presence of visible light, oxygen and a dye or photosensitizer (PS). Several PS have been studied for their ability to bind to bacteria and efficiently generate reactive oxygen species (ROS) upon photostimulation. ROS are formed through type I or II mechanisms and may inactivate several classes of microbial cells including Gram-negative bacteria such as Pseudomonas aeruginosa, which are typically characterized by an impermeable outer cell membrane that contains endotoxins and blocks antibiotics, dyes, and detergents, protecting the sensitive inner membrane and cell wall. This review covers significant peer-reviewed articles together with US and World patents that were filed within the past few years and that relate to the eradication of Gram-negative bacteria via PDI or PDT. It is organized mainly according to the nature of the PS involved and includes natural or synthetic food dyes; cationic dyes such as methylene blue and toluidine blue; tetrapyrrole derivatives such as phthalocyanines, chlorins, porphyrins, chlorophyll and bacteriochlorophyll derivatives; functionalized fullerenes; nanoparticles combined with different PS; other formulations designed to target PS to bacteria; photoactive materials and surfaces; conjugates between PS and polycationic polymers or antibodies; and permeabilizing agents such as EDTA, PMNP and CaCl2. The present review also covers the different laboratory animal models normally used to treat Gram-negative bacterial infections with antimicrobial PDT. PMID

  16. Staphylococcus epidermidis strategies to avoid killing by human neutrophils.

    Directory of Open Access Journals (Sweden)

    Gordon Y C Cheung

    2010-10-01

    Full Text Available Staphylococcus epidermidis is a leading nosocomial pathogen. In contrast to its more aggressive relative S. aureus, it causes chronic rather than acute infections. In highly virulent S. aureus, phenol-soluble modulins (PSMs contribute significantly to immune evasion and aggressive virulence by their strong ability to lyse human neutrophils. Members of the PSM family are also produced by S. epidermidis, but their role in immune evasion is not known. Notably, strong cytolytic capacity of S. epidermidis PSMs would be at odds with the notion that S. epidermidis is a less aggressive pathogen than S. aureus, prompting us to examine the biological activities of S. epidermidis PSMs. Surprisingly, we found that S. epidermidis has the capacity to produce PSMδ, a potent leukocyte toxin, representing the first potent cytolysin to be identified in that pathogen. However, production of strongly cytolytic PSMs was low in S. epidermidis, explaining its low cytolytic potency. Interestingly, the different approaches of S. epidermidis and S. aureus to causing human disease are thus reflected by the adaptation of biological activities within one family of virulence determinants, the PSMs. Nevertheless, S. epidermidis has the capacity to evade neutrophil killing, a phenomenon we found is partly mediated by resistance mechanisms to antimicrobial peptides (AMPs, including the protease SepA, which degrades AMPs, and the AMP sensor/resistance regulator, Aps (GraRS. These findings establish a significant function of SepA and Aps in S. epidermidis immune evasion and explain in part why S. epidermidis may evade elimination by innate host defense despite the lack of cytolytic toxin expression. Our study shows that the strategy of S. epidermidis to evade elimination by human neutrophils is characterized by a passive defense approach and provides molecular evidence to support the notion that S. epidermidis is a less aggressive pathogen than S. aureus.

  17. Can patriotism justify killing in defense of one’s country?

    Directory of Open Access Journals (Sweden)

    Pavković Aleksandar

    2007-01-01

    Full Text Available Cosmopolitan liberals would be ready to fight - and to kill and be killed for the sake of restoring international justice or for the abolition of profoundly unjust political institutions. Patriots are ready to do the same for their own country. Sometimes the cosmopolitan liberals and patriots would fight on the same side and sometimes on the opposite sides of the conflict. Thus the former would join the latter in the defense of Serbia against Austria-Hungary (in 1914 but would oppose the white Southerner patriots in the American Civil War (in 1861. In this paper I argue that fighting and killing for one’s country is, in both of those cases, different from the defense of one’s own life and the lives of those who cannot defend themselves. Killing for one’s country is killing in order to fulfill a particular political preference. The same is the case with fighting for the abolition of a profoundly unjust political institution. It is not amoral or immoral to refuse to kill for any one of these two political preferences because there is no reason to believe that either political preference trumps our moral constraints against killing.

  18. Commuting symmetry operators of the Dirac equation, Killing-Yano and Schouten-Nijenhuis brackets

    International Nuclear Information System (INIS)

    Cariglia, Marco; Krtous, Pavel; Kubiznak, David

    2011-01-01

    In this paper we derive the most general first-order symmetry operator commuting with the Dirac operator in all dimensions and signatures. Such an operator splits into Clifford even and Clifford odd parts which are given in terms of odd Killing-Yano and even closed conformal Killing-Yano inhomogeneous forms, respectively. We study commutators of these symmetry operators and give necessary and sufficient conditions under which they remain of the first-order. In this specific setting we can introduce a Killing-Yano bracket, a bilinear operation acting on odd Killing-Yano and even closed conformal Killing-Yano forms, and demonstrate that it is closely related to the Schouten-Nijenhuis bracket. An important nontrivial example of vanishing Killing-Yano brackets is given by Dirac symmetry operators generated from the principal conformal Killing-Yano tensor [hep-th/0612029]. We show that among these operators one can find a complete subset of mutually commuting operators. These operators underlie separability of the Dirac equation in Kerr-NUT-(A)dS spacetimes in all dimensions [arXiv:0711.0078].

  19. Kill rate of mastitis pathogens by a combination of cefalexin and kanamycin.

    Science.gov (United States)

    Maneke, E; Pridmore, A; Goby, L; Lang, I

    2011-01-01

    To assess the bacterial killing rate produced by a combination of cefalexin and kanamycin at two different concentration ratios. Time-kill kinetics of cefalexin and kanamycin, individually and in combination, were determined against one strain each of Escherichia coli, Staphylococcus aureus, Streptococcus agalactiae, Streptococcus dysgalactiae and Streptococcus uberis. The combination was tested using two fixed ratios (cefalexin : kanamycin ratios of 1·25 : 1 and 1 : 2·3) and two concentrations of each ratio. Time-kill curves produced with either ratio were quite similar. Against most bacterial species, higher concentrations produced faster kill. In all cases, the combination of cefalexin and kanamycin showed faster and greater kill at lower antibiotic concentrations than those observed with either drug alone. The combination of cefalexin and kanamycin results in a fast initial killing of major mastitis pathogens at both concentration ratios. The combination of cefalexin and kanamycin achieved rapid bacterial kill at concentrations and ratios that can be achieved in vivo following intramammary infusion of a mastitis treatment. © 2010 Boehringer Ingelheim Vetmedica GmbH. Journal of Applied Microbiology © 2010 The Society for Applied Microbiology.

  20. Mechanisms of Bacterial (Serratia marcescens) Attachment to, Migration along, and Killing of Fungal Hyphae.

    Science.gov (United States)

    Hover, Tal; Maya, Tal; Ron, Sapir; Sandovsky, Hani; Shadkchan, Yana; Kijner, Nitzan; Mitiagin, Yulia; Fichtman, Boris; Harel, Amnon; Shanks, Robert M Q; Bruna, Roberto E; García-Véscovi, Eleonora; Osherov, Nir

    2016-05-01

    We have found a remarkable capacity for the ubiquitous Gram-negative rod bacterium Serratia marcescens to migrate along and kill the mycelia of zygomycete molds. This migration was restricted to zygomycete molds and several basidiomycete species. No migration was seen on any molds of the phylum Ascomycota. S. marcescens migration did not require fungal viability or surrounding growth medium, as bacteria migrated along aerial hyphae as well.S. marcescens did not exhibit growth tropism toward zygomycete mycelium. Bacterial migration along hyphae proceeded only when the hyphae grew into the bacterial colony. S. marcescens cells initially migrated along the hyphae, forming attached microcolonies that grew and coalesced to generate a biofilm that covered and killed the mycelium. Flagellum-defective strains of S. marcescens were able to migrate along zygomycete hyphae, although they were significantly slower than the wild-type strain and were delayed in fungal killing. Bacterial attachment to the mycelium does not necessitate type 1 fimbrial adhesion, since mutants defective in this adhesin migrated equally well as or faster than the wild-type strain. Killing does not depend on the secretion of S. marcescens chitinases, as mutants in which all three chitinase genes were deleted retained wild-type killing abilities. A better understanding of the mechanisms by which S. marcescens binds to, spreads on, and kills fungal hyphae might serve as an excellent model system for such interactions in general; fungal killing could be employed in agricultural fungal biocontrol. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  1. Killing of Pseudomonas aeruginosa by Chicken Cathelicidin-2 Is Immunogenically Silent, Preventing Lung Inflammation In Vivo

    Science.gov (United States)

    Coorens, Maarten; Banaschewski, Brandon J. H.; Baer, Brandon J.; Yamashita, Cory; van Dijk, Albert; Veldhuizen, Ruud A. W.; Veldhuizen, Edwin J. A.

    2017-01-01

    ABSTRACT The development of antibiotic resistance by Pseudomonas aeruginosa is a major concern in the treatment of bacterial pneumonia. In the search for novel anti-infective therapies, the chicken-derived peptide cathelicidin-2 (CATH-2) has emerged as a potential candidate, with strong broad-spectrum antimicrobial activity and the ability to limit inflammation by inhibiting Toll-like receptor 2 (TLR2) and TLR4 activation. However, as it is unknown how CATH-2 affects inflammation in vivo, we investigated how CATH-2-mediated killing of P. aeruginosa affects lung inflammation in a murine model. First, murine macrophages were used to determine whether CATH-2-mediated killing of P. aeruginosa reduced proinflammatory cytokine production in vitro. Next, a murine lung model was used to analyze how CATH-2-mediated killing of P. aeruginosa affects neutrophil and macrophage recruitment as well as cytokine/chemokine production in the lung. Our results show that CATH-2 kills P. aeruginosa in an immunogenically silent manner both in vitro and in vivo. Treatment with CATH-2-killed P. aeruginosa showed reduced neutrophil recruitment to the lung as well as inhibition of cytokine and chemokine production, compared to treatment with heat- or gentamicin-killed bacteria. Together, these results show the potential for CATH-2 as a dual-activity antibiotic in bacterial pneumonia, which can both kill P. aeruginosa and prevent excessive inflammation. PMID:28947647

  2. Mitigation options for fish kills in L Lake and Pond C

    International Nuclear Information System (INIS)

    Paller, M.H.

    1989-11-01

    This report concerns mitigation options for reducing or eliminating the fish kills that occur in L Lake and Pond C as a result of reactor operations. These kills occur when fish that have entered the discharge areas during outages are killed by the rapid rises in temperature that follow reactor re-starts. Factors that have been observed to influence the severity of the kills include the length of the outage, season during which the outage occurs, reactor power level, and size of the fish in the discharge area. Without mitigation, fish kills can be expected to occur in Pond C with approximately the same frequency and severity as in the past. Even in the absence of mitigation, however, it is unlikely that future fish kills in L Lake will be as severe as the large kill that occurred in December 1986. Fish abundance in Region 2 of L Lake (where severe kills occurred in the past) has declined over 90% since 1986, largely due to a reduction in the abundance of juvenile sunfish (which constituted approximately 99% of past kills). There are basically three categories of mitigation options: changes in reactor operations, methods to exclude fish from time discharge areas, and methods to promote the escapement of fish from the discharge area. These options vary in approach, scope, and anticipated expense. Most would need to be researched in greater depth before it would be possible to predict their effectiveness more definitively. While the options have the potential to greatly reduce mortalities, none can totally eliminate mortalities. The only way of ensuring the elimination of all mortalities is to reduce effluent temperatures to sublethal levels with properly designed and operated cooling technology. 18 refs., 2 figs., 1 tab

  3. An exploration of the connection between two meaning perspectives: an evidence-based approach to health information delivery to vulnerable groups of Arabic- and Somali-speaking asylum seekers in a Swedish context.

    Science.gov (United States)

    Ekblad, Solvig; Linander, Andrea; Asplund, Maria

    2012-09-01

    The right to health care is significant for asylum seekers, particularly as many of them have experienced traumatic life events in their home country, during flight or in their host country. Post-migration living conditions have more impact than pre-migration conditions on ill health among asylum seekers, which underscores the importance of health care-related refugee reception policies. The purpose of this article is to explore the perceived meaning of comprehensive health information provided by a nurse to Arabic- and Somali-speaking adult asylum seekers, in a Swedish context, during its introduction at the Migration Board. In our study, the endpoint was whether asylum seekers found such health information relevant, understandable and respectful. Following an oral presentation, participants filled in a questionnaire consisting of three close-ended questions. A total of 39 groups of presentation attendees included 626 asylum seekers (415 Arabic- and 211 Somali-speaking). Data were analysed with descriptive statistics. Comments underwent content analysis. We also present some socio-demographic data on these asylum seekers. Independently of gender and language, the participants expressed their gratitude for and the meaningfulness of receiving professional, fact-based information, as well as being treated with concern and respect. They indicated a great need for this and felt relieved by being listened to. They liked the pedagogic group method, the opportunity for dialogue and to practice exercising their rights. These promising results indicate that exercising the asylum-seekers' right to receive such health information would improve future reception policies not only in Sweden, but throughout the EU. A renewed focus on communication and pedagogic skills, instead of just cultural training, should be considered for health care professionals assisting asylum seekers.

  4. Prevalence of alcohol and other psychoactive substances in injured and killed drivers

    DEFF Research Database (Denmark)

    Isalberti, Cristina; Linden, Trudy Van der; Legrand, Sara-Ann

    2011-01-01

    regarding the prevalence of alcohol and other psychoactive substances in drivers who have been injured/killed in traffic accidents. Part 1 of this report presents the general results of the hospital & killed driver studies. After a short introduction, the representativeness of the populations in the EU...... countries as well as the representativeness of hospitalised and killed driver samples are addressed. An overview of the non-response issues in the various countries is also included. Based on the toxicological findings, a general summary of the prevalence of drug use is given for the 9 participating...

  5. 43 CFR 30.251 - What happens if an heir or devisee participates in the killing of the decedent?

    Science.gov (United States)

    2010-10-01

    ... participates in the killing of the decedent? 30.251 Section 30.251 Public Lands: Interior Office of the... if an heir or devisee participates in the killing of the decedent? Any person who knowingly participates, either as a principal or as an accessory before the fact, in the willful and unlawful killing of...

  6. Efeitos genéticos aditivos e não-aditivos em características de crescimento, reprodutivas e habilidade materna em ovinos das raças Santa Inês, Somalis Brasileira, Dorper e Poll Dorset Additive and non-additive genetic effects on growth, reproductive and maternal traits in sheep of Santa In��s, Brazilian Somali, Dorper and Poll Dorset breeds

    Directory of Open Access Journals (Sweden)

    Adriano Caminha Barbosa Neto

    2010-09-01

    Full Text Available Efeitos genético aditivo, de dominância e de recombinação em cruzamentos entre as raças Santa Inês (SI, Somalis Brasileira (So, Dorper (Do e Poll Dorset (Po foram estimados para as características de crescimento, reprodutivas e de habilidade materna. Os dados foram obtidos da Gaasa e Alimentos LTDA, uma empresa que participa do Programa de Melhoramento Genético de Caprinos e Ovinos (GENECOC da Embrapa Caprinos. Inicialmente, 3.573 registros foram analisados por meio do procedimento MIXED do pacote estatístico SAS (1999. As análises foram realizadas considerando os efeitos da diferença genética aditiva entre as raças, de dominância e de recombinação. O peso ao nascer foi influenciado pelos efeitos genéticos aditivos, enquanto o peso ao desmame e o ganho de peso pré-desmame foram influenciados por efeitos genéticos não-aditivos. A estimativa de herdabilidade direta para o peso ao nascer foi moderada, o que indica a existência de variabilidade genética passível de ser explorada por meio da seleção individual. Do mesmo modo, as estimativas de herdabilidade das características idade ao primeiro parto e peso total das crias ao nascer indicaram a existência de variabilidade genética para obter ganhos genéticos por meio da seleção. Os genes das raças Poll Dorset e Dorper tiveram papel importante para melhor desempenho ponderal, portanto, essas raças podem ser indicadas como paternas no cruzamento terminal. A utilização de matrizes F1 Santa Inês x Somalis Brasileira em cruzamentos com reprodutores Poll Dorset pode levar a maior eficiência reprodutiva.Additive genetic, dominance and recombination effects in breedings among Santa Inês (SI, Brazilian Somali (So, Dorper (Do and Poll Dorset (Po breeds were estimated for growth, reproductive and maternal hability traits. Data were obtained from Gaasa e Alimentos LTDA, a company that participates on the Programa de Melhoramento Genético de Caprinos e Ovinos (GENECOC

  7. A CHALLENGE OF TRUST: CAN DISTRUST KILL THE EURO?

    Directory of Open Access Journals (Sweden)

    Nataliia Kostiuchenko

    2015-11-01

    Full Text Available The purpose of the paper is to determine the dynamics of trust in the ECB in the most recent period, to compare the findings with a previous study of Farvaque et al. (2010 and to explore the question of importance of citizen’s trust in public institution for the economic performance of the country. This paper is dedicated to the study of the determinants of trust in the European Central Bank. The study attempts to give an answer to a question posed in introduction: can distrust kill the euro? After the world economic crisis the trust in the ECB began to deteriorate. Citizen’s trust in public institutions plays an important role for the economic performance of the country. Methology. We rely on the micro data from the European Commission’s Eurobarometer survey. This paper contributes empirically to the existing literature dedicated to the issue of trust in public institutions. The responses in 15 EU-member countries were taken into account. The present work uses the model of Farvaque et al. (2010 extending the time frame considered previously, giving a broader picture on this issue using the most recent data. Results. In accordance with our findings, the population that support the ECB is approximately equal to the population that does not trust in the community bank, with a mean value of 0,51. Even if there are still more supporters of the ECB, this data should provide an alarm for the European institutional framework, in consideration that in 1999 (in accordance with Farvaque et al. (2010 the mean value was 0,67. Practical implications. According to our findings, still people with higher level of education, people with a higher social status, people with center or right-wing political orientation, people with optimistic expectations on the economic situation have more trust in the ECB. However, we have found that women have become more supportive about the ECB than men in contrast with the findings of Farvaque et al. (2010. Value

  8. The 1965 Indonesian Killing Discourse by Generation 2000 Writers

    Directory of Open Access Journals (Sweden)

    Diah Ariani Arimbi

    2011-06-01

    Full Text Available The fall of Soeharto’s authority in 1998 has indeed impacted numerous sides of Indonesian life: political, social and cultural. The shifting of authoritative government to the state of “reformation” and “democratization” has forced the nation to redefine its authority to its members. This paper aims to look at these public responses which are narrated in contemporary Indonesian fiction. Although fiction may be seen as imaginative production, discursive ideologies can be examined clearly. By examining thematic significant of the narratives about G30S/PKI and the killings aftermath in the literary writings published in post 1998 by contemporary Indonesia writers, who are known as the Generation 2000 writers (who were mostly born in 1970s at least five years after the 1965 incident: also known as the millennials, this paper will attempt to answer whether or not this generation presents shift and creates its own notions of the incident. Abstrak: Jatuhnya kekuasaan Soeharto pada tahun 1998 berdampak pada berbagai sisi kehidupan di Indonesia: politik, sosial, dan budaya. Pergeseran dari pemerintahan yang dulunya otoritatif menjadi pemerintahan yang sarat dengan "reformasi" dan "demokratisasi" telah memaksa negara untuk mendefinisikan kembali wewenangnya kepada para anggotanya. Makalah ini bertujuan untuk melihat respons publik yang diceritakan dalam fiksi Indonesia kontemporer. Walaupun fiksi dapat dipandang sebagai produk imajinatif, ideologi diskursif dapat dilihat dengan je-las. Dengan memeriksa tema-tema yang secara signifikan dimunculkan dari narasi tentang G30S/PKI dan tragedi pembunuhan sesudahnya dalam tulisan-tulisan sastra yang diterbitkan pasca tahun 1998 oleh penulis Indonesia kontemporer, yang dikenal sebagai penulis Generasi 2000 (penulis yang kebanyakan lahir di tahun 1970-an setidaknya 5 tahun setelah 1965 kejadian: juga dikenal sebagai millenials, makalah ini berusaha menjawab apakah generasi baru mengalami pergeseran dalam

  9. [gammadelta T cells stimulated by zoledronate kill osteosarcoma cells].

    Science.gov (United States)

    Jiang, Hui; Xu, Qiang; Yang, Chao; Cao, Zhen-Guo; Li, Zhao-Xu; Ye, Zhao-Ming

    2010-12-01

    To investigate the cytotoxicity of human γδT cells from PBMCs stimulated by zoledronate against osteosarcoma cell line HOS in vitro and in vivo and evaluate the relavent pathways. The peripheral blood mononuclear cells (PBMCs)of healthy donors were stimulated by single dose zoledronate and cultured in the present of IL-2 for two weeks, analysising the percentage of γδT cells on a FACSCalibur cytometer.Study the cytotoxicity of γδT cells against the osteosarcoma line HOS using LDH release assay kit. Pre-treatment of γδT cells with anti-human γδTCR antibody, anti-human NKG2D antibody and concanamycin A to bolck the relavent pathways for evaluating the mechenisms of its cytotoxicity. In vivo, BALB/c mice were inoculated subcutaneously osteosarcoma cell HOS for developing hypodermal tumors. And they were randomized into two groups: unteated group, γδT cell therapy group. Tumor volume and weight of the two groups were compared. After two weeks of culture, γδT cells from zoledronate-stimulated PBMCs could reach (95±3)%. When the E:T as 6:1, 12:1, 25:1, 50:1, the percentage of osteosarcoma cell HOS killed by γδT cells was 26.8%, 31.5%, 37.8%, 40.9%, respectively.When anti-huma γδTCR antibody, anti-human NKG2D antibody and concanamycin A blocked the relavent pathways, the percentage was 32.3%, 4.7%, 16.7% ( E:T as 25:1), respectively. In vivo, the tumor inhibition rate of the group of γδT cell therapy was 42.78%. γδT cells derived from PBMCs stimulated by zoledronate can acquired pure γδT cells. And they show strong cytoxicity against osteosarcoma cell line HOS in vitro and in vivo.

  10. Hot tensile behaviour in silicon-killed boron microalloyed steels

    Science.gov (United States)

    Chown, Lesley H.; Cornish, Lesley A.

    2017-10-01

    Low carbon steel for drawing and cold heading applications should have low strength, high ductility and low strain ageing rates. To achieve this, nitrogen must be removed from solid solution, which can be done by low additions of boron. A wire producer had been experiencing occasional problems with severe cracking on silicon-killed, boron steel billets during continuous casting, but the solution was not obvious. Samples from four billets, each from different casts, were removed for analysis and testing. The tested steel compositions were within the specification limits, with boron to nitrogen ratios of 0.40-1.19. Hot ductility testing was performed on a Gleeble 1500 using parameters approximating the capabilities of this particular billet caster. The steel specimens were subjected to in situ melting, then cooled at a rate of 2 C.s-1 to temperatures in the range 750-1250°C, where they were then pulled to failure at a strain rate of 8x10-4 s-1. In this work, it was found that both the boron to nitrogen ratio and the manganese to sulphur ratio influenced the hot ductility and hence the crack susceptibility. Excellent hot ductility was found for B:N ratios above 1.0, which confirmed that the B:N ratio should be above a stoichiometric value of 0.8 to remove all nitrogen from solid solution. TEM analysis showed that coarse BN precipitates nucleated on other precipitates, such as (Fe,Mn)S, which have relatively low melting points, and are detrimental to hot ductility. Low Mn:S ratios of 10 - 12 were shown to promote precipitation of FeS, so a Mn:S > 14 was recommended. A narrower billet surface temperature range for straightening was recommended to prevent transverse surface cracking. Additionally, analysis of industrial casting data showed that the scrap percentage due to transverse cracking increased significantly for Mn:S < 14. An exponential decay relationship between the manganese to sulphur ratio and the average scrap percentage due to transverse cracking was

  11. Pathogen analysis of NYSDOT road-killed deer carcass compost facilities.

    Science.gov (United States)

    2008-09-01

    Composting of deer carcasses was effective in reducing pathogen levels, decomposing the : carcasses and producing a useable end product after 12 months. The composting process used in this project : involved enveloping the carcasses of road-killed de...

  12. Optimal Fixed-Interval Integrated Guidance-Control Laws for Hit-to-Kill Missiles

    National Research Council Canada - National Science Library

    Menon, P. K; Sweriduk, G. D; Ohlmeyer, E. J

    2003-01-01

    Due to their potential for reducing the weapon size and efficiency, design methods for realizing hit-to- kill capabilities in missile systems are of significant research interest in the missile flight control community...

  13. IN VITRO KILLING OF PERKINSUS MARINUS BY HEMOCYTES OF OYSTERS CRASSOSTREA VIRGINICA

    Science.gov (United States)

    A colorimetric microbicidal assay was adapted, optimized and applied in experiments to characterize the in vitro capacity of eastern oyster (Crassostrea virginica) hemocytes to kill cultured isolates of Perkinsus marinus, a protozoan parasite causing a highly destructive disease...

  14. Novel contaminants identified in fish kills in the Red River watershed, 2011–2013

    Science.gov (United States)

    Provisional molecular weights and chemical formulas were assigned to four significant previously unidentified contaminants present during active fish kills in the Red River region of Oklahoma. The provisional identifications of these contaminants were determined using high-resolu...

  15. Time-kill profiles and cell-surface morphological effects of crude ...

    African Journals Online (AJOL)

    Methods: Time-kill assays were conducted by incubating test bacteria with the extract and sampling at selected time points within ... activity against both bacteria and fungi [14]. Also, a protein ..... be developed as novel drugs for the treatment of.

  16. Research on killing Escherichia Coli by reactive oxygen species based on strong ionization discharging plasma

    International Nuclear Information System (INIS)

    Li, Y J; Tian, Y P; Zhang, Z T; Li, R H; Cai, L J; Gao, J Y

    2013-01-01

    Reactive oxygen species solution produced by strong ionization discharging plasma was used to kill Escherichia coli by spraying. Several effect factors such as pH value, solution temperature, spraying time and exposure time were observed in this study, and their effects on killing rate of Escherichia coli were discussed and analysed. Results show that the treating efficiency of ROS solution for Escherichia coli is higher in alkaline solution than that in acid solution. The killing rate of Escherichia coli increases while the spraying time and exposure time are longer and the temperature is lower. The effects of different factors on killing rate of Escherichia coli are as follows: spraying time > pH value > exposure time > solution temperature.

  17. Nurses Writing about Psychiatric Nurses' Involvement in Killings during the Nazi Era: A Preliminary Discourse Analysis.

    Science.gov (United States)

    Holmes, Colin A; McAllister, Margaret; Crowther, Andrew

    2016-01-01

    Nurses actively killed people in Nazi Europe between 1939 and 1945. The so-called ‘science of eugenics’ underpinned Nazi ideology, used to further the Nazi racist agenda. Edicts sanctioned selection and medically supervised killing of people, and nurses, principally in mental hospitals, participated in the killing of between 100–300 thousand patients. Erroneously termed ‘euthanasia', there were three phases: the initial programme involving children, the T4 adult programme, and ‘wild euthanasia'. Unofficial killings also took place before 1939. This paper uses discourse analysis to map and analyse published texts which explore the role of nurses in Nazi Germany. The aim is to identify its characteristics as a body of literature, to note strengths and weaknesses, emphases and silences, and to note aspects that need further exploration. It acknowledges that how these events are to be understood and represented in contemporary discourse constitutes a significant problem for historians of nursing.

  18. Targeted Killing as an Element of U.S. Foreign Policy in the War On Terror

    National Research Council Canada - National Science Library

    Machon, Matthew J

    2006-01-01

    ...) launched a lethal missile strike, killing Qaed Salim Sinan al-Harethi, a high ranking al-Qaeda member and suspected architect of the USS Cole bombing, in an isolated and sparsely populated region within Yemen...

  19. The curvature and the algebra of Killing vectors in five-dimensional space

    International Nuclear Information System (INIS)

    Rcheulishvili, G.

    1990-12-01

    This paper presents the Killing vectors for a five-dimensional space with the line element. The algebras which are formed by these vectors are written down. The curvature two-forms are described. (author). 10 refs

  20. Time-kill profiles and cell-surface morphological effects of crude ...

    African Journals Online (AJOL)

    MK1201 mycelial extract on the viability and cell surface morphology of methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA). Methods: Time-kill assays were conducted by incubating test ...

  1. From Attitudes to Actions: Predictors of Lion Killing by Maasai Warriors

    OpenAIRE

    Hazzah, Leela; Bath, Alistair; Dolrenry, Stephanie; Dickman, Amy; Frank, Laurence

    2017-01-01

    Despite legal protection, deliberate killing by local people is one of the major threats to the conservation of lions and other large carnivores in Africa. Addressing this problem poses particular challenges, mainly because it is difficult to uncover illicit behavior. This article examined two groups of Maasai warriors: individuals who have killed African lions (Panthera leo) and those who have not. We conducted interviews to explore the relationship between attitudes, intentions and known li...

  2. ANALYZE THE IMPACT OF HABITAT PATCHES ON WILDLIFE ROAD-KILL

    OpenAIRE

    Seok, S.; Lee, J.

    2015-01-01

    The ecosystem fragmentation due to transportation infrastructure causes a road-kill phenomenon. When making policies for mitigating road-kill it is important to select target-species in order to enhance its efficiency. However, many wildlife crossing structures have been questioned regarding their effectiveness due to lack of considerations such as target-species selection, site selection, management, etc. The purpose of this study is to analyse the impact of habitat patches on wildlife road-...

  3. Landscape integration of freeways: how does it affect road kill rates?

    OpenAIRE

    Sanz, Luis

    2001-01-01

    Some ecological processes are affected by the transportation infrastructure development. The barrier effect caused by roads, which alters the movement patterns of terrestrial wildlife and increases its road kill risk, is just an example. Road kills must be considered both from environmental and highway safety perspectives, and are related to road permeability and to the surrounding environment. This paper compares the landscape fragmentation caused by two freeways in Navarra (north of Spain) ...

  4. Habitat or matrix: which is more relevant to predict road-kill of vertebrates?

    Directory of Open Access Journals (Sweden)

    C. Bueno

    Full Text Available Abstract We believe that in tropics we need a community approach to evaluate road impacts on wildlife, and thus, suggest mitigation measures for groups of species instead a focal-species approach. Understanding which landscape characteristics indicate road-kill events may also provide models that can be applied in other regions. We intend to evaluate if habitat or matrix is more relevant to predict road-kill events for a group of species. Our hypothesis is: more permeable matrix is the most relevant factor to explain road-kill events. To test this hypothesis, we chose vertebrates as the studied assemblage and a highway crossing in an Atlantic Forest region in southeastern Brazil as the study site. Logistic regression models were designed using presence/absence of road-kill events as dependent variables and landscape characteristics as independent variables, which were selected by Akaike’s Information Criterion. We considered a set of candidate models containing four types of simple regression models: Habitat effect model; Matrix types effect models; Highway effect model; and, Reference models (intercept and buffer distance. Almost three hundred road-kills and 70 species were recorded. River proximity and herbaceous vegetation cover, both matrix effect models, were associated to most road-killed vertebrate groups. Matrix was more relevant than habitat to predict road-kill of vertebrates. The association between river proximity and road-kill indicates that rivers may be a preferential route for most species. We discuss multi-species mitigation measures and implications to movement ecology and conservation strategies.

  5. Enhanced oxidative killing of azole-resistant Candida glabrata strains with ERG11 deletion.

    Science.gov (United States)

    Kan, V L; Geber, A; Bennett, J E

    1996-01-01

    The susceptibility of genetically defined Candida glabrata strains to killing by H2O2 and neutrophils was assessed. Fluconazole-susceptible L5L and L5D strains demonstrated survival rates higher than those of two fluconazole-resistant strains lacking the ERG11 gene coding for 14 alpha-demethylase. Fluconazole resistance can occur by mechanisms which increase fungal susceptibility to oxidative killing by H2O2 and neutrophils. PMID:8807069

  6. Subordinations In “To Kill A Mockingbird” By Harper Lee

    OpenAIRE

    Siregar, Rut Sri Novitawaty

    2011-01-01

    Salah satu yang dipelajari mahasiswa adalah tulis menulis. Secara ilmiah tulis menulis adalah penyampaian informasi dalam bentuk tulisan serta bagaimana informasi itu disampaikan. Judul kertas karya ini adalah Kalimat Subordinat yang ditemukan dalam novel To Kill a Mockingbird karya Harper Lee: SUBORDINATION IN TO KILL A MOCKINGBIRD BY HARPER LEE. Penulis mengangkat hal ini karena penulis tertarik dengan bentuk–bentuk serta fungsi-fungsi kalimat subordinat yang terdapat dalam tulisan-tulisan ...

  7. Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis.

    Science.gov (United States)

    Credito, Kim L; Ednie, Lois M; Appelbaum, Peter C

    2008-01-01

    Against 447 anaerobe strains, the investigational carbapenem doripenem had an MIC 50 of 0.125 microg/ml and an MIC 90 of 1 microg/ml. Results were similar to those for imipenem, meropenem, and ertapenem. Time-kill studies showed that doripenem had very good bactericidal activity compared to other carbapenems, with 99.9% killing of 11 strains at 2x MIC after 48 h.

  8. Comparative Antianaerobic Activities of Doripenem Determined by MIC and Time-Kill Analysis▿

    Science.gov (United States)

    Credito, Kim L.; Ednie, Lois M.; Appelbaum, Peter C.

    2008-01-01

    Against 447 anaerobe strains, the investigational carbapenem doripenem had an MIC50 of 0.125 μg/ml and an MIC90 of 1 μg/ml. Results were similar to those for imipenem, meropenem, and ertapenem. Time-kill studies showed that doripenem had very good bactericidal activity compared to other carbapenems, with 99.9% killing of 11 strains at 2× MIC after 48 h. PMID:17938185

  9. Killing in Combat: Utilizing a Christian Perspective, When is a Soldier Justified in Taking a Life?

    Science.gov (United States)

    2014-06-13

    Vietnam War combat veterans suffering from PTSD, has to say concerning subjects such as grief, guilt , honor, suffering, and healing while investigating...Gray, who served as an intelligence 11 officer in World War I, offers his thoughts on death and killing while discussing the guilt Soldiers so...battlefield (1959, 104). Gray also discusses the need for hating one’s enemy while having pride in the number of kills on the battlefield as a necessity

  10. Vacuum spacetimes with a spacelike, hypersurface-orthogonal Killing vector: reduced equations in a canonical frame

    International Nuclear Information System (INIS)

    Bonanos, S

    2003-01-01

    The Newman-Penrose equations for spacetimes having one spacelike Killing vector are reduced-in a geometrically defined 'canonical frame' - to a minimal set, and its differential structure is studied. Expressions for the frame vectors in an arbitrary coordinate basis are given, and coordinate-independent choices of the metric functions are suggested which make the components of the Ricci tensor in the direction of the Killing vector vanish

  11. Road kills of amphibians in different land use areas from Sharavathi river basin, central Western Ghats, India

    Directory of Open Access Journals (Sweden)

    K.S. Seshadri

    2009-11-01

    Full Text Available A survey of amphibian mortality on roads was carried out in the Sharavathi river basin in the central Western Ghats. Road kills in three different land use areas: agricultural fields, water bodies and forests were recorded for four days along three 100m stretches in each type of area. One-hundred-and-forty-four individuals belonging to two orders, eight families, 11 genera and 13 species were recorded in the survey. Kills/km observed were: in forest 55, agricultural fields 38 and water bodies 27, for an overall average of 40 kills/km. Kill species compositions varied significantly between land use areas, but not overall kill rates.

  12. Human Neutrophils Use Different Mechanisms To Kill Aspergillus fumigatus Conidia and Hyphae: Evidence from Phagocyte Defects.

    Science.gov (United States)

    Gazendam, Roel P; van Hamme, John L; Tool, Anton T J; Hoogenboezem, Mark; van den Berg, J Merlijn; Prins, Jan M; Vitkov, Ljubomir; van de Veerdonk, Frank L; van den Berg, Timo K; Roos, Dirk; Kuijpers, Taco W

    2016-02-01

    Neutrophils are known to play a pivotal role in the host defense against Aspergillus infections. This is illustrated by the prevalence of Aspergillus infections in patients with neutropenia or phagocyte functional defects, such as chronic granulomatous disease. However, the mechanisms by which human neutrophils recognize and kill Aspergillus are poorly understood. In this work, we have studied in detail which neutrophil functions, including neutrophil extracellular trap (NET) formation, are involved in the killing of Aspergillus fumigatus conidia and hyphae, using neutrophils from patients with well-defined genetic immunodeficiencies. Recognition of conidia involves integrin CD11b/CD18 (and not dectin-1), which triggers a PI3K-dependent nonoxidative intracellular mechanism of killing. When the conidia escape from early killing and germinate, the extracellular destruction of the Aspergillus hyphae needs opsonization by Abs and involves predominantly recognition via Fcγ receptors, signaling via Syk, PI3K, and protein kinase C to trigger the production of toxic reactive oxygen metabolites by the NADPH oxidase and myeloperoxidase. A. fumigatus induces NET formation; however, NETs did not contribute to A. fumigatus killing. Thus, our findings reveal distinct killing mechanisms of Aspergillus conidia and hyphae by human neutrophils, leading to a comprehensive insight in the innate antifungal response. Copyright © 2016 by The American Association of Immunologists, Inc.

  13. Assisted suicide and the killing of people? Maybe. Physician-assisted suicide and the killing of patients? No: the rejection of Shaw's new perspective on euthanasia.

    Science.gov (United States)

    McLachlan, Hugh V

    2010-05-01

    David Shaw presents a new argument to support the old claim that there is not a significant moral difference between killing and letting die and, by implication, between active and passive euthanasia. He concludes that doctors should not make a distinction between them. However, whether or not killing and letting die are morally equivalent is not as important a question as he suggests. One can justify legal distinctions on non-moral grounds. One might oppose physician-assisted suicide and active euthanasia when performed by doctors on patients whether or not one is in favour of the legalisation of assisted suicide and active euthanasia. Furthermore, one can consider particular actions to be contrary to appropriate professional conduct even in the absence of legal and ethical objections to them. Someone who wants to die might want only a doctor to kill him or to help him to kill himself. However, we are not entitled to everything that we want in life or death. A doctor cannot always fittingly provide all that a patient wants or needs. It is appropriate that doctors provide their expert advice with regard to the performance of active euthanasia but they can and should do so while, qua doctors, they remain hors de combat.

  14. Activity of telithromycin (HMR 3647) against anaerobic bacteria compared to those of eight other agents by time-kill methodology.

    Science.gov (United States)

    Credito, K L; Ednie, L M; Jacobs, M R; Appelbaum, P C

    1999-08-01

    Time-kill studies examined the activities of telithromycin (HMR 3647), erythromycin A, azithromycin, clarithromycin, roxithromycin, clindamycin, pristinamycin, amoxicillin-clavulanate, and metronidazole against 11 gram-positive and gram-negative anaerobic bacteria. Time-kill studies were carried out with the addition of Oxyrase in order to prevent the introduction of CO(2). Macrolide-azalide-ketolide MICs were 0.004 to 32.0 microg/ml. Of the latter group, telithromycin had the lowest MICs, especially against non-Bacteroides fragilis group strains, followed by azithromycin, clarithromycin, erythromycin A, and roxithromycin. Clindamycin was active (MIC /=99.9% killing) against 6 strains, with 99% killing of 9 strains and 90% killing of 10 strains. After 24 h at twice the MIC, 90, 99, and 99.9% killing of nine, six, and three strains, respectively, occurred. Lower rates of killing were seen at earlier times. Similar kill kinetics relative to the MIC were seen with other macrolides. After 48 h at the MIC, clindamycin was bactericidal against 8 strains, with 99 and 90% killing of 9 and 10 strains, respectively. After 24 h, 90% killing of 10 strains occurred at the MIC. The kinetics of clindamycin were similar to those of pristinamycin. After 48 h at the MIC, amoxicillin-clavulanate showed 99.9% killing of seven strains, with 99% killing of eight strains and 90% killing of nine strains. At four times the MIC, metronidazole was bactericidal against 8 of 10 strains tested after 48 h and against all 10 strains after 24 h; after 12 h, 99% killing of all 10 strains occurred.

  15. How Effective Is Road Mitigation at Reducing Road-Kill? A Meta-Analysis.

    Science.gov (United States)

    Rytwinski, Trina; Soanes, Kylie; Jaeger, Jochen A G; Fahrig, Lenore; Findlay, C Scott; Houlahan, Jeff; van der Ree, Rodney; van der Grift, Edgar A

    2016-01-01

    Road traffic kills hundreds of millions of animals every year, posing a critical threat to the populations of many species. To address this problem there are more than forty types of road mitigation measures available that aim to reduce wildlife mortality on roads (road-kill). For road planners, deciding on what mitigation method to use has been problematic because there is little good information about the relative effectiveness of these measures in reducing road-kill, and the costs of these measures vary greatly. We conducted a meta-analysis using data from 50 studies that quantified the relationship between road-kill and a mitigation measure designed to reduce road-kill. Overall, mitigation measures reduce road-kill by 40% compared to controls. Fences, with or without crossing structures, reduce road-kill by 54%. We found no detectable effect on road-kill of crossing structures without fencing. We found that comparatively expensive mitigation measures reduce large mammal road-kill much more than inexpensive measures. For example, the combination of fencing and crossing structures led to an 83% reduction in road-kill of large mammals, compared to a 57% reduction for animal detection systems, and only a 1% for wildlife reflectors. We suggest that inexpensive measures such as reflectors should not be used until and unless their effectiveness is tested using a high-quality experimental approach. Our meta-analysis also highlights the fact that there are insufficient data to answer many of the most pressing questions that road planners ask about the effectiveness of road mitigation measures, such as whether other less common mitigation measures (e.g., measures to reduce traffic volume and/or speed) reduce road mortality, or to what extent the attributes of crossing structures and fences influence their effectiveness. To improve evaluations of mitigation effectiveness, studies should incorporate data collection before the mitigation is applied, and we recommend a

  16. How Effective Is Road Mitigation at Reducing Road-Kill? A Meta-Analysis.

    Directory of Open Access Journals (Sweden)

    Trina Rytwinski

    Full Text Available Road traffic kills hundreds of millions of animals every year, posing a critical threat to the populations of many species. To address this problem there are more than forty types of road mitigation measures available that aim to reduce wildlife mortality on roads (road-kill. For road planners, deciding on what mitigation method to use has been problematic because there is little good information about the relative effectiveness of these measures in reducing road-kill, and the costs of these measures vary greatly. We conducted a meta-analysis using data from 50 studies that quantified the relationship between road-kill and a mitigation measure designed to reduce road-kill. Overall, mitigation measures reduce road-kill by 40% compared to controls. Fences, with or without crossing structures, reduce road-kill by 54%. We found no detectable effect on road-kill of crossing structures without fencing. We found that comparatively expensive mitigation measures reduce large mammal road-kill much more than inexpensive measures. For example, the combination of fencing and crossing structures led to an 83% reduction in road-kill of large mammals, compared to a 57% reduction for animal detection systems, and only a 1% for wildlife reflectors. We suggest that inexpensive measures such as reflectors should not be used until and unless their effectiveness is tested using a high-quality experimental approach. Our meta-analysis also highlights the fact that there are insufficient data to answer many of the most pressing questions that road planners ask about the effectiveness of road mitigation measures, such as whether other less common mitigation measures (e.g., measures to reduce traffic volume and/or speed reduce road mortality, or to what extent the attributes of crossing structures and fences influence their effectiveness. To improve evaluations of mitigation effectiveness, studies should incorporate data collection before the mitigation is applied, and we

  17. How Effective Is Road Mitigation at Reducing Road-Kill? A Meta-Analysis

    Science.gov (United States)

    Rytwinski, Trina; Soanes, Kylie; Jaeger, Jochen A. G.; Fahrig, Lenore; Findlay, C. Scott; Houlahan, Jeff; van der Ree, Rodney; van der Grift, Edgar A

    2016-01-01

    Road traffic kills hundreds of millions of animals every year, posing a critical threat to the populations of many species. To address this problem there are more than forty types of road mitigation measures available that aim to reduce wildlife mortality on roads (road-kill). For road planners, deciding on what mitigation method to use has been problematic because there is little good information about the relative effectiveness of these measures in reducing road-kill, and the costs of these measures vary greatly. We conducted a meta-analysis using data from 50 studies that quantified the relationship between road-kill and a mitigation measure designed to reduce road-kill. Overall, mitigation measures reduce road-kill by 40% compared to controls. Fences, with or without crossing structures, reduce road-kill by 54%. We found no detectable effect on road-kill of crossing structures without fencing. We found that comparatively expensive mitigation measures reduce large mammal road-kill much more than inexpensive measures. For example, the combination of fencing and crossing structures led to an 83% reduction in road-kill of large mammals, compared to a 57% reduction for animal detection systems, and only a 1% for wildlife reflectors. We suggest that inexpensive measures such as reflectors should not be used until and unless their effectiveness is tested using a high-quality experimental approach. Our meta-analysis also highlights the fact that there are insufficient data to answer many of the most pressing questions that road planners ask about the effectiveness of road mitigation measures, such as whether other less common mitigation measures (e.g., measures to reduce traffic volume and/or speed) reduce road mortality, or to what extent the attributes of crossing structures and fences influence their effectiveness. To improve evaluations of mitigation effectiveness, studies should incorporate data collection before the mitigation is applied, and we recommend a

  18. Targeting hunter distribution based on host resource selection and kill sites to manage disease risk.

    Science.gov (United States)

    Dugal, Cherie J; van Beest, Floris M; Vander Wal, Eric; Brook, Ryan K

    2013-10-01

    Endemic and emerging diseases are rarely uniform in their spatial distribution or prevalence among cohorts of wildlife. Spatial models that quantify risk-driven differences in resource selection and hunter mortality of animals at fine spatial scales can assist disease management by identifying high-risk areas and individuals. We used resource selection functions (RSFs) and selection ratios (SRs) to quantify sex- and age-specific resource selection patterns of collared (n = 67) and hunter-killed (n = 796) nonmigratory elk (Cervus canadensis manitobensis) during the hunting season between 2002 and 2012, in southwestern Manitoba, Canada. Distance to protected area was the most important covariate influencing resource selection and hunter-kill sites of elk (AICw = 1.00). Collared adult males (which are most likely to be infected with bovine tuberculosis (Mycobacterium bovis) and chronic wasting disease) rarely selected for sites outside of parks during the hunting season in contrast to adult females and juvenile males. The RSFs showed selection by adult females and juvenile males to be negatively associated with landscape-level forest cover, high road density, and water cover, whereas hunter-kill sites of these cohorts were positively associated with landscape-level forest cover and increasing distance to streams and negatively associated with high road density. Local-level forest was positively associated with collared animal locations and hunter-kill sites; however, selection was stronger for collared juvenile males and hunter-killed adult females. In instances where disease infects a metapopulation and eradication is infeasible, a principle goal of management is to limit the spread of disease among infected animals. We map high-risk areas that are regularly used by potentially infectious hosts but currently underrepresented in the distribution of kill sites. We present a novel application of widely available data to target hunter distribution based on host resource

  19. Complement-mediated killing of Borrelia burgdorferi by nonimmune sera from sika deer.

    Science.gov (United States)

    Nelson, D R; Rooney, S; Miller, N J; Mather, T N

    2000-12-01

    Various species of cervid deer are the preferred hosts for adult, black-legged ticks (Ixodes scapularis and Ixodes pacificus) in the United States. Although frequently exposed to the agent of Lyme disease (Borrelia burgdorferi), these animals, for the most part, are incompetent as transmission reservoirs. We examined the borreliacidal activity of normal and B. burgdorferi-immune sera from sika deer (Cervus nippon) maintained in a laboratory setting and compared it to that of similar sera from reservoir-competent mice and rabbits. All normal deer sera (NDS) tested killed > 90% of B. burgdorferi cells. In contrast, normal mouse and rabbit sera killed feeding exhibited IFA titers of 1:256, whereas sera from mice and rabbits similarly exposed had titers of > 1:1,024. Heat treatment (56 C, 30 min) of NDS reduced borreliacidal activity, with complement-mediated killing. The chelators EGTA and EDTA were used to block the classical or both the classical and alternative complement pathways, respectively. Addition of 10 mM EGTA to NDS had a negligible effect on borreliacidal activity, with > 90% of the cells killed. Addition of 10 mM EDTA reduced the killing to approximately 30%, whereas the addition of Mg2+ (10 mM) restored borreliacidal activity to NDS. The addition of zymosan A, an activator of the alternative pathway, increased the survival of B. burgdorferi cells to approximately 80% in NDS. These data suggest that the alternative complement activation pathway plays a major role in the borreliacidal activity of NDS. Additionally, 10 mM EGTA had almost no effect on the killing activity of B. burgdorferi-exposed deer sera, suggesting that the classical pathway is not involved in Borrelia killing, even in sera from B. burgdorferi-exposed deer.

  20. Effect of Silicon on Desulfurization of Aluminum-killed Steels

    Science.gov (United States)

    Roy, Debdutta

    Recent reports have suggested that silicon has a beneficial effect on the rate of desulfurization of Al-killed steel. This effect is difficult to understand looking at the overall desulfurization reaction which does not include silicon. However an explanation is proposed by taking into account the (SiO2)/[Si] equilibrium in which some Al reaching the slag-metal interface is used in reducing the SiO2 in the slag. This reaction can be suppressed to some extent if the silicon content of the metal is increased and in doing so, more Al will be available at the slag-metal interface for the desulfurization reaction and this would increase the rate of the desulfurization reaction. A model was developed, assuming the rates are controlled by mass transfer, taking into account the coupled reactions of the reduction of silica, and other unstable oxides, namely iron oxide and manganese oxide, in the slag and desulfurization reaction in the steel by aluminum. The model predicts that increasing silicon increases the rate and extent of desulfurization. Plant data was analyzed to obtain rough estimates of ladle desulfurization rates and also used to validate the model predictions. Experiments have been conducted on a kilogram scale of material in an induction furnace to test the hypothesis. The major conclusions of the study are as follows: The rate and extent of desulfurization improve with increasing initial silicon content in the steel; the effect diminishes at silicon contents higher than approximately 0.2% and with increasing slag basicity. This was confirmed with kilogram-scale laboratory experiments. The effects of the silicon content in the steel (and of initial FeO and MnO in the slag) largely arise from the dominant effects of these reactions on the equilibrium aluminum content of the steel: as far as aluminum consumption or pick-up is concerned, the Si/SiO2 reaction dominates, and desulfurization has only a minor effect on aluminum consumption. The rate is primarily