Sample records for small group charge

  1. Charge space, exceptional observables and groups

    International Nuclear Information System (INIS)

    Guersey, F.


    It is shown that a class of exceptional quantum mechanical spaces represented by octonionic matrices and first introduced by Jordan, von Neumann and Wigner are suitable for representing the states of basic fermionic constituents (leptons and quarks) of elementary particles. In these exceptional spaces, the transformation groups that leave scalar products invariant are the exceptional groups. A gauge field theory based on E 7 is given as an example for the unification of weak, electromagnetic and strong interactions

  2. Determining the maximum charging currents of lithium-ion cells for small charge quantities (United States)

    Grimsmann, F.; Gerbert, T.; Brauchle, F.; Gruhle, A.; Parisi, J.; Knipper, M.


    In order to optimize the operating parameters of battery management systems for electric and hybrid vehicles, great interest has been shown in achieving the maximum permissible charging currents during recuperation, without causing a cell damage due to lithium plating, in relation to the temperature, charge quantity and state of charge. One method for determining these recuperation currents is measuring the cell thickness, where excessively high charging currents can be detected by an irreversible increase in thickness. It is not possible to measure particularly small charge quantities by employing mechanic dial indicators, which have a limited resolution of 1 μm. This is why we developed a measuring setup that has a resolution limit of less than 10 nm using a high-resolution contactless inductance sensor. Our results show that the permissible charging current I can be approximated in relation to the charge quantity x by a correlating function I =a /√{(x) } which is compliant with the Arrhenius law. Small charge quantities therefore have an optimization potential for energy recovery during recuperation.

  3. Small Group Multitasking in Literature Classes (United States)

    Baurain, Bradley


    Faced with the challenge of teaching American literature to large, multilevel classes in Vietnam, the writer developed a flexible small group framework called "multitasking". "Multitasking" sets up stable task categories which rotate among small groups from lesson to lesson. This framework enabled students to work cooperatively…

  4. Small Business Administration (SBA) Loan Program Performance- Post-Charge Off Recovery Rates by Program (United States)

    Small Business Administration — Reflects total post-charge off recovery rates, as a percent of the amounts charged off by charge off year, for the major loan programs and aggregate totals by charge...

  5. Charged Particle Tracking and Vertex Detection Group summary report

    International Nuclear Information System (INIS)

    Hanson, G.; Meyer, D.


    Charged particle tracking is essential in order to investigate the new physics expected at the SSC. The Tracking Group studied radiation damage and rate limitations to tracking devices, vertex detectors, and central tracking. The Group concluded that silicon strips and large wire tracking chambers with small cells can probably survive at the design luminosity of 10 33 cm -2 sec -1 ; however, the presently designed electronics for silicon strip vertex detectors can withstand a luminosity of only 10 31 cm -2 sec -1 . Wire chambers at a radius of less than about 25 cm can withstand a luminosity of less than or equal to 10 32 cm -2 sec -1 only. Actual tracking and pattern recognition in central tracking chambers at a luminosity of 10 33 cm -2 sec -1 will be very difficult because of multiple interactions within the resolving time of the chambers; detailed simulations are needed in order to decide whether tracking is indeed possible at this luminosity. Scintillating glass fibers are an interesting possibility both for vertex detectors and for central trackers, but much research and development is still needed both on the fibers themselves and on the readout

  6. Affect and Engagement during Small Group Instruction (United States)

    Linnenbrink-Garcia, Lisa; Rogat, Toni Kempler; Koskey, Kristin L. K.


    Two studies (Study 1: n = 137; Study 2: n = 192) were conducted to investigate how upper-elementary students' affect during small group instruction related to their social-behavioral engagement during group work. A circumplex model of affect consisting of valence (positive, negative) and activation (high, low) was used to examine the relation of…

  7. Direct quantification of negatively charged functional groups on membrane surfaces

    KAUST Repository

    Tiraferri, Alberto


    Surface charge plays an important role in membrane-based separations of particulates, macromolecules, and dissolved ionic species. In this study, we present two experimental methods to determine the concentration of negatively charged functional groups at the surface of dense polymeric membranes. Both techniques consist of associating the membrane surface moieties with chemical probes, followed by quantification of the bound probes. Uranyl acetate and toluidine blue O dye, which interact with the membrane functional groups via complexation and electrostatic interaction, respectively, were used as probes. The amount of associated probes was quantified using liquid scintillation counting for uranium atoms and visible light spectroscopy for the toluidine blue dye. The techniques were validated using self-assembled monolayers of alkanethiols with known amounts of charged moieties. The surface density of negatively charged functional groups of hand-cast thin-film composite polyamide membranes, as well as commercial cellulose triacetate and polyamide membranes, was quantified under various conditions. Using both techniques, we measured a negatively charged functional group density of 20-30nm -2 for the hand-cast thin-film composite membranes. The ionization behavior of the membrane functional groups, determined from measurements with toluidine blue at varying pH, was consistent with published data for thin-film composite polyamide membranes. Similarly, the measured charge densities on commercial membranes were in general agreement with previous investigations. The relative simplicity of the two methods makes them a useful tool for quantifying the surface charge concentration of a variety of surfaces, including separation membranes. © 2011 Elsevier B.V.

  8. Small Group Teaching in Epidemiology Courses

    Directory of Open Access Journals (Sweden)

    Azita Goshtasebi


    Full Text Available Background and purpose: small group teaching(SGT in is a known method for developing intellectual skills, changing attitudes and encouraging the taking of responsibilities for learning. This study was an attempt to compare students’ attitudes and knowledge scores on SGT and lecture -based teaching (LBT.Methods: 22 first year medical students were enrolled in a course using two methods (lecture- based and small group discussion for teaching basic epidemiology. Data about attitudes and knowledge scores of the two methods were collected at the end of the course and analyzed using a two-sided Wilcoxon test.Results: The students were satisfied and preferred SGT in terms of Evaluation method for the course, Participatory learning and team working, effectiveness and developing self learning skills (p<0.001,and scored higher on topics of SGT(p<0.01, but believed that they needed longer discussion of the topics.Conclusion: Better question design and course organization and creating a safe, comfortable environment is essential for good performance. Integrating this teaching strategy in medical education curricula with appropriate professional and organizational development is suggested.Key words: MEDICAL EDUCATION, SMALL GROUP TEACHING, COURSE EVALUATION

  9. Optimizing small wind turbine performance in battery charging applications (United States)

    Drouilhet, Stephen; Muljadi, Eduard; Holz, Richard; Gevorgian, Vahan


    Many small wind turbine generators (10 kW or less) consist of a variable speed rotor driving a permanent magnet synchronous generator (alternator). One application of such wind turbines is battery charging, in which the generator is connected through a rectifier to a battery bank. The wind turbine electrical interface is essentially the same whether the turbine is part of a remote power supply for telecommunications, a standalone residential power system, or a hybrid village power system, in short, any system in which the wind generator output is rectified and fed into a DC bus. Field experience with such applications has shown that both the peak power output and the total energy capture of the wind turbine often fall short of expectations based on rotor size and generator rating. In this paper, the authors present a simple analytical model of the typical wind generator battery charging system that allows one to calculate actual power curves if the generator and rotor properties are known. The model clearly illustrates how the load characteristics affect the generator output. In the second part of this paper, the authors present four approaches to maximizing energy capture from wind turbines in battery charging applications. The first of these is to determine the optimal battery bank voltage for a given WTG. The second consists of adding capacitors in series with the generator. The third approach is to place an optimizing DC/DC voltage converter between the rectifier and the battery bank. The fourth is a combination of the series capacitors and the optimizing voltage controller. They also discuss both the limitations and the potential performance gain associated with each of the four configurations.

  10. Temperature Dependence of Charge Localization in High-Mobility, Solution-Crystallized Small Molecule Semiconductors Studied by Charge Modulation Spectroscopy

    DEFF Research Database (Denmark)

    Meneau, Aurélie Y. B.; Olivier, Yoann; Backlund, Tomas


    In solution-processable small molecule semiconductors, the extent of charge carrier wavefunction localization induced by dynamic disorder can be probed spectroscopically as a function of temperature using charge modulation spectroscopy (CMS). Here, it is shown based on combined fi eld-effect tran......In solution-processable small molecule semiconductors, the extent of charge carrier wavefunction localization induced by dynamic disorder can be probed spectroscopically as a function of temperature using charge modulation spectroscopy (CMS). Here, it is shown based on combined fi eld...

  11. Small wind generators for battery charging in Peru and Sri Lanka

    Energy Technology Data Exchange (ETDEWEB)

    Dunnett, S. [Intermediate Technology Development Group, Rugby (United Kingdom)


    The Intermediate Technology Development Group (ITDG) have developed a small wind generator (SWG) intended primarily for battery charging in Peru and Sri Lanka. The project is funded mainly by the Department for International Development (DfID) and aims to provide rural households and communities who do not have access to mains electricity with a form of electrification. This paper reports on progress to date and is correct at the time of going to press, but subsequent changes to specifications may occur. (Author)

  12. The Role of Small Groups in Christian Adult Education. (United States)

    Peters, Russel Marion

    Centering on a historical review and analysis of adult Christian education in small groups, this study was designed to identify certain conditions surrounding the formation and operation of selected small groups, to discover their distinctive educational features, and to suggest guidelines for effective use of the small group approach. The role of…

  13. Assessment Intelligence in Small Group Learning (United States)

    Xing, Wanli; Wu, Yonghe


    Assessment of groups in CSCL context is a challenging task fraught with many confounding factors collected and measured. Previous documented studies are by and large summative in nature and some process-oriented methods require time-intensive coding of qualitative data. This study attempts to resolve these problems for teachers to assess groups…

  14. Orientation and Mobility Training Using Small Groups (United States)

    Higgerty, Moira Jane; Williams, Allison Catherine


    This article describes a group training program for sighted trainee orientation and mobility (O&M) instructors in South Africa, where the need for O&M instructors is great and the availability of services is limited. The outcome was positive and encouraging and provides the initiative for the findings to be more broadly applied and for…

  15. Small group presentations for each session

    International Nuclear Information System (INIS)


    This section presents the results of the questionnaires with the recommendations from the 3 discussion groups. The questions approached are as follows: 1 - Discussion Group 1, 2 and 3 - Senior Management / Organizational Issues: Do Senior Managers understand the root cause analysis (RCA) process? Who in the organization is responsible for RCA? Are there regulatory requirements / influence? Does the culture of the organization affect the RCA process? Specific Recommendations. 2 - Discussion Group 1, 2 and 3 - Systematic Methodology / Tools: What are the challenges in using available analyses tools for identification of Human and Organisational Factors (HOF) in RCA? How do you 'handle' the perceived qualitative/subjective nature of HOF? Is the vocabulary used in RCA methodologies consistent? Will organizational issues be identified in analyses less intensive than RCA? Are you able to identify organizational issues from a single event? Is it difficult to make a clear link between RCA and CAs? What do you do if your scope expands? Recommendations. 3 - Discussion Group 1, 2 and 3 - Team Composition / Attributes: What are the challenges associated in team / individual competence? Is there management / HOF representation on the team? Does the level of the management sponsor affect the willingness of the organization to accept the HOF in RCA? Are RCA results presented to management? Who presents? Recommendations. 4 - Discussion Group 1, 2 and 3 - Learning: How many RCAs are done in a year? Is this sufficient? Could you identify organizational issues using an 'Apparent Cause Analysis' method? Are events with HOF issues trended in your organization? How do you know you have a learning organization? How can you measure the effectiveness of CAs?

  16. Small-Group Instruction. Theory and Practice (United States)


    Resources Research Organization, Alexandria, Virginia, June 1963. Lange, Carl J., Rittenhouse, Carl H., Atkinson, Richard C. Films and Group Discussions as a...sentation or class discussion. 13. References Beckhard , R. How to Plan and Conduct Workshops and Conferences, Associated Press, New York, 1956, pp. 35-37...Harper and Bibliographic Review, Industrial Brothers, New York, 1954. Relations Center, University of Chicago, Beckhard , R. How to Plan and Conduct

  17. The Use of Ferroelectric Ceramics to Charge Small Capacitor Banks (United States)


    mounted the FEG to the edge of the sandwich using a machined coupler, and the second mounted the FEG to the face of the sandwich. The peak charge...distribution is unlimited. iii Contents List of Figures iv List of Tables iv 1. Introduction 1 2. Background 1 3. Material 2 4. Experimental Setup...Fig. 6 Edge shock experiment orientation with lateral FEG placement.......... 6 Fig. 7 Face shock experiment orientation with longitudinal FEG

  18. Increasing Social Presence in Online Learning through Small Group Discussions (United States)

    Akcaoglu, Mete; Lee, Eunbae


    Social presence is difficult to achieve, but an imperative component of online learning. In this study, we investigated the effect of group size on students' perceptions of social presence in two graduate-level online courses, comparing small group versus whole class discussions. Our results indicated that when in small group discussions, students…

  19. Small amplitude variable charge dust Bernstein-Greene-Kruskal double layers

    Energy Technology Data Exchange (ETDEWEB)

    Amour, Rabia [Plasma Physics Group, Theoretical Physics Laboratory, Faculty of Sciences - Physics, U.S.T.H.B, Bab-Ezzouar, B.P. 32, El Alia, Algiers 16111 (Algeria); Tribeche, Mouloud [Plasma Physics Group, Theoretical Physics Laboratory, Faculty of Sciences - Physics, U.S.T.H.B, Bab-Ezzouar, B.P. 32, El Alia, Algiers 16111 (Algeria)], E-mail:


    A first theoretical attempt is made to investigate small amplitude, variable charge dust Bernstein-Greene-Kruskal (BGK) double layers (DLs). The nature of the dust BGK-DLs (compressive or rarefactive), their strength and thickness depend sensitively on the net negative charge residing on the grain surface, the dust grain dynamics and, more interestingly, on the ion-to-electron temperatures ratio.

  20. Small amplitude variable charge dust Bernstein-Greene-Kruskal double layers

    International Nuclear Information System (INIS)

    Amour, Rabia; Tribeche, Mouloud


    A first theoretical attempt is made to investigate small amplitude, variable charge dust Bernstein-Greene-Kruskal (BGK) double layers (DLs). The nature of the dust BGK-DLs (compressive or rarefactive), their strength and thickness depend sensitively on the net negative charge residing on the grain surface, the dust grain dynamics and, more interestingly, on the ion-to-electron temperatures ratio.

  1. Small-Scale Renewable Energy Converters for Battery Charging

    Directory of Open Access Journals (Sweden)

    Mohd Nasir Ayob


    Full Text Available This paper presents two wave energy concepts for small-scale electricity generation. In the presented case, these concepts are installed on the buoy of a heaving, point-absorbing wave energy converter (WEC for large scale electricity production. In the studied WEC, developed by Uppsala University, small-scale electricity generation in the buoy is needed to power a tidal compensating system designed to increase the performance of the WEC in areas with high tides. The two considered and modeled concepts are an oscillating water column (OWC and a heaving point absorber. The results indicate that the OWC is too small for the task and does not produce enough energy. On the other hand, the results show that a hybrid system composed of a small heaving point absorber combined with a solar energy system would be able to provide a requested minimum power of around 37.7 W on average year around. The WEC and solar panel complement each other, as the WEC produces enough energy by itself during wintertime (but not in the summer, while the solar panel produces enough energy in the summer (but not in the winter.

  2. Effectiveness of Small Group Social Skills Lessons with Elementary Students (United States)

    Chupp, Amy I.; Boes, Susan R.


    This action research study (ARS) describes the effectiveness of small group social skills lessons with elementary students, using "Too Good for Violence: A Curriculum for Non-violent Living" by the Mendez Foundation. The school counselor and school social worker taught the curriculum in a structured small group of 4th grade students in 8…

  3. Teaching Small Group Communication: The Do Good Project (United States)

    Minei, Elizabeth M.


    This paper focuses on the parameters of a semester-long project called the "Do Good" project, geared towards developing small group communication skills in undergraduate students. This project highlights participation in a social engagement project that allows students to bridge concepts learned in small group communication lectures…

  4. Emergent Leaders and Small Groups in the EFL Classroom (United States)

    Leeming, Ian Paul


    Small groups are integral for many activities in the foreign language classroom and their pedagogical importance is well established. Despite the widespread use of groups in foreign language education, there is a dearth of research investigating group processes and the impact of emergent leaders within these groups. This mixed-methods,…

  5. Cooperative behavior evolution of small groups on interconnected networks

    International Nuclear Information System (INIS)

    Huang, Keke; Cheng, Yuan; Zheng, Xiaoping; Yang, Yeqing


    Highlights: • Small groups are modeled on interconnected networks. • Players face different dilemmas inside and outside small groups. • Impact of the ratio and strength of link on the behavioral evolution are studied. - Abstract: Understanding the behavioral evolution in evacuation is significant for guiding and controlling the evacuation process. Based on the fact that the population consists of many small groups, here we model the small groups which are separated in space but linked by other methods, such as kinship, on interconnected networks. Namely, the players in the same layer belong to an identical small group, while the players located in different layers belong to different small groups. And the players of different layers establish interaction by edge crossed layers. In addition, players face different dilemmas inside and outside small groups, in detail, the players in the same layer play prisoner’s dilemma, but players in different layers play harmony game. By means of numerous simulations, we study the impact of the ratio and strength of link on the behavioral evolution. Because the framework of this work takes the space distribution into account, which is close to the realistic life, we hope that it can provide a new insight to reveal the law of behavioral evolution of evacuation population.

  6. Charging and absorption characteristics of small particulates under alternative and electrostatic voltages in an electrostatic precipitator

    International Nuclear Information System (INIS)

    Jiang Xue-Dong; Xu He; Wang Xin


    The charge quantity of small particulates such as PM2.5 plays a key role in the collection efficiency of an electrostatic precipitator (ESP). Under a single electrostatic voltage, it is difficult to charge and absorb small particulates. A new method of superimposing an alternative voltage on the electrostatic voltage is provided in this paper. Characteristics of small particulates are analyzed under alternative and electrostatic voltages. It is demonstrated that an alternative voltage can significantly improve the collection efficiency in three aspects: preventing anti-corona, increasing the charge quantity of small particulates, and increasing the median particulate size by electric agglomeration. In addition, practical usage with the superposition of alternative voltage is provided, and the results are in agreement with the theoretical analysis. (physics of gases, plasmas, and electric discharges)

  7. Implicit Contracts Regulating Small Group Leadership: The Influence of Culture. (United States)

    Zamarripa, Perrin Orr; Krueger, Dorothy Lenk


    Examined culture variables in the negotiation of implicit rules which govern leadership behavior in small groups. American, French, and Arab students (N=42) were assigned identical decision-making tasks. Results showed monocultural groups presented homogeneous rules governing leadership prior to interaction, while intercultural groups presented…

  8. A Cooperative Small-Group Methodology in the Language Classroom. (United States)

    Bejarano, Yael


    Assessment of the effects of two small-group cooperative techniques and the whole-class method on academic achievement in English as a foreign language for seventh-graders (N=665) revealed that the group methods (Discussion Group and Student Teams and Achievement Divisions) registered significantly greater improvement than the whole-class method.…

  9. Working Group 2 Summary:. Space Charge Effects in Bending Systems (United States)

    Bohn, Courtlandt L.; Emma, Paul J.


    Participants in Working Group 2 included: Y. Batygin, C. Bohn, B. Carlsten, J. Ellison, P. Emma, Z. Huang, A. Kabel, R. Kishek, R. Li, P. Musumeci, S. Nagaitsev, J. Qiang, M. Reiser, A. Ruggerio, R. Warnock, and M. Zeitlin.

  10. Influence of functional groups on charge transport in molecular junctions

    DEFF Research Database (Denmark)

    Mowbray, Duncan; Jones, Glenn; Thygesen, Kristian Sommer


    Using density functional theory (DFT), we analyze the influence of five classes of functional groups, as exemplified by NO2, OCH3, CH3, CCl3, and I, on the transport properties of a 1,4-benzenedithiolate (BDT) and 1,4-benzenediamine (BDA) molecular junction with gold electrodes. Our analysis...... demonstrates how ideas from functional group chemistry may be used to engineer a molecule's transport properties, as was shown experimentally and using a semiempirical model for BDA [Nano Lett. 7, 502 (2007)]. In particular, we show that the qualitative change in conductance due to a given functional group can...... be predicted from its known electronic effect (whether it is sigma/pi donating/withdrawing). However, the influence of functional groups on a molecule's conductance is very weak, as was also found in the BDA experiments. The calculated DFT conductances for the BDA species are five times larger than...

  11. Enhancing Leadership Abilities through Small-Group Activities. (United States)

    Parise, James; Culp, William


    The article describes a 14-week program (one hour per week) of the Punxsutawney (Pennsylvania) schools in which 29 gifted high school students learned and practiced fundamentals of small group dynamics to enhance their leadership abilities. (DB)

  12. Nonexistence in Thomas-Fermi-Dirac-von Weizsäcker Theory with Small Nuclear Charges

    Energy Technology Data Exchange (ETDEWEB)

    Nam, Phan Thành, E-mail: [Institute of Science and Technology Austria (Austria); Den Bosch, Hanne Van, E-mail: [Pontificia Universidad Católica de Chile, Instituto de Física (Chile)


    We study the ionization problem in the Thomas-Fermi-Dirac-von Weizsäcker theory for atoms and molecules. We prove the nonexistence of minimizers for the energy functional when the number of electrons is large and the total nuclear charge is small. This nonexistence result also applies to external potentials decaying faster than the Coulomb potential. In the case of arbitrary nuclear charges, we obtain the nonexistence of stable minimizers and radial minimizers.

  13. Searching for Intertextual Connections in Small Group Text Discussion (United States)

    Chi, Feng-ming


    This paper reports the sources for and intentions of intertextuality made by 10 groups of Taiwanese university students in the process of discussing two American stories. Two types of data, small group text discussions and oral interviews, were gathered. The results indicated that participants used diverse sources of intertextual links, and with…

  14. Teaching Small Group Communication: A Do Good Project

    Directory of Open Access Journals (Sweden)

    Elizabeth M. Minei, PhD


    Full Text Available This paper focuses on the parameters of a semester-long project called the “Do Good” project, geared towards developing small group communication skills in undergraduate students. This project highlights participation in a social engagement project that allows students to bridge concepts learned in small group communication lectures (e.g., team dynamics, project management, conflict resolution, decision making, leadership with community outreach. Included are an overview of the project, and examples for how each component both challenges students’ ability to communicate in groups and provides motivation that foster students’ ability to link in-class knowledge with practical, real world application.

  15. Small-Group Learning in Undergraduate STEM Disciplines: Effect of Group Type on Student Achievement (United States)

    Micari, Marina; Pazos, Pilar; Streitwieser, Bernhard; Light, Gregory


    Small-group learning in the science, technology, engineering, and mathematics (STEM) disciplines has been widely studied, and it is clear that this method offers many benefits to students. Less attention has been paid to the ways in which small learning groups differ from one another, and how these differences may affect student learning and…

  16. Group purchasing of workplace health promotion services for small employers. (United States)

    Harris, Jeffrey R; Hammerback, Kristen R; Hannon, Peggy A; McDowell, Julie; Katzman, Avi; Clegg-Thorp, Catherine; Gallagher, John


    Small employers are underserved with workplace health promotion services, so we explored the potential for group purchasing of these services. We conducted semistructured telephone interviews of member organizations serving small employers, as well as workplace health promotion vendors, in Washington State. We interviewed 22 employer organizations (chambers of commerce, trade associations, and an insurance trust) and vendors (of fitness facilities, healthy vending machines, fresh produce delivery, weight management services, and tobacco cessation quitlines). Both cautiously supported the idea of group purchasing but felt that small employers' workplace health promotion demand must increase first. Vendors providing off-site services, for example, quitline, found group purchasing more feasible than vendors providing on-site services, for example, produce delivery. Employer member organizations are well-positioned to group purchase workplace health promotion services; vendors are receptive if there is potential profit.

  17. Net Based Examination: Small Group Tutoring, Home Assignments, and Large Group Automatic and Peer Assessment

    Directory of Open Access Journals (Sweden)

    G. Karlsson


    Full Text Available This paper deals with net based examination,tutoring and scaffolding of groups of different sizes: Firstfor very small groups, then for normal sized groups around100 students and finally for very large groups. The threedifferent methods can be applied to internationally basedcourses. Methods which support deep learning throughtutoring, scaffolding, project work and peer learning arealso mentioned.

  18. Meta-analysis of targeted small-group reading interventions. (United States)

    Hall, Matthew S; Burns, Matthew K


    Small-group reading interventions are commonly used in schools but the components that make them effective are still debated or unknown. The current study meta-analyzed 26 small-group reading intervention studies that resulted in 27 effect sizes. Findings suggested a moderate overall effect for small-group reading interventions (weighted g=0.54). Interventions were more effective if they were targeted to a specific skill (g=0.65), then as part of a comprehensive intervention program that addressed multiple skills (g=0.35). There was a small correlation between intervention effects and group size (r=0.21) and duration (r=0.11). Small-group interventions led to a larger median effect size (g=0.64) for elementary-aged students than for those in middle or high school (g=0.20), but the two confidence intervals overlapped. Implications for research and practice are discussed. Copyright © 2017 Society for the Study of School Psychology. Published by Elsevier Ltd. All rights reserved.

  19. Solar small-scale dynamo and polarity of sunspot groups (United States)

    Sokoloff, D.; Khlystova, A.; Abramenko, V.


    In order to clarify a possible role of small-scale dynamo in formation of solar magnetic field, we suggest an observational test for small-scale dynamo action based on statistics of anti-Hale sunspot groups. As we have shown, according to theoretical expectations the small-scale dynamo action has to provide a population of sunspot groups which do not follow the Hale polarity law, and the density of such groups on the time-latitude diagram is expected to be independent on the phase of the solar cycle. Correspondingly, a percentage of the anti-Hale groups is expected to reach its maximum values during solar minima. For several solar cycles, we considered statistics of anti-Hale groups obtained by several scientific teams, including ours, to find that the percentage of anti-Hale groups becomes indeed maximal during a solar minimum. Our interpretation is that this fact may be explained by the small-scale dynamo action inside the solar convective zone.


    Directory of Open Access Journals (Sweden)

    Kurniawan Yudhi Nugroho


    Full Text Available Success of learning is not only a matter of using an appropriate teaching resources, instead, the interference of teaching method is found to be essential to determine the students’ learning achievement. Teacher as a captain of class has the right to choose type of method used in the classroom for sake of students’ improvement. This study was designed as an attempt to help Master Students from a well established private university improve their reading comprehension skill through small group discussion. This study was participated by 30 students, later divided into two classes and served differently as an experimental group for the class A and a control group for the class B. Referring to the final data analysis of the study, it is found that there is an improving learning achievement in the experimental group, indicated by higher performance of posttest (20.333 than the pretest. Apart from this, further analysis was also conducted to find out whether or not small group discussion was able to show better performance than another teaching method applied in another different class. Based on the result of statistical calculation, it shows that small group discussion got better result 12.334 than that of another group. As a result, some suggestions were made by referring to result of the study.

  1. Metastable structures and size effects in small group dynamics

    Directory of Open Access Journals (Sweden)

    Rosapia eLauro Grotto


    Full Text Available In his seminal works on group dynamics Bion defined a specific therapeutic setting allowing psychoanalytic observations on group phenomena. In describing the setting he proposed that the group was where his voice arrived. This physical limit was later made operative by assuming that the natural dimension of a therapeutic group is around 12 people. Bion introduced a theory of the group aspects of the mind in which proto-mental individual states spontaneously evolve into shared psychological states that are characterized by a series of features: 1 they emerge as a consequence of the natural tendency of (both conscious and unconscious emotions to combine into structured group patterns; 2 they have a certain degree of stability in time; 3 they tend to alternate so that the dissolution of one is rapidly followed by the emergence of another; 4 they can be described in qualitative terms according to the nature of the emotional mix that dominates the state, in structural terms by a kind of typical 'leadership’ pattern, and in 'cognitive’ terms by a set of implicit expectations that are helpful in explaining the group behavior (i.e. the group behaves 'as if’ it was assuming that…. Here we adopt a formal approach derived from Socio-physics in order to explore some of the structural and dynamic properties of this small group dynamics. We will described data from an analytic DS model simulating small group interactions of agents endowed with a very simplified emotional and cognitive dynamic in order to assess the following main points: 1 are metastable collective states allowed to emerge in the model and if so, under which conditions in the parameter space? 3 can these states be differentiated in structural terms? 3 to what extent are the emergent dynamic features of the systems dependent of the system size? We will finally discuss possible future applications of the quantitative descriptions of the interaction structure in the small group clinical

  2. Metastable structures and size effects in small group dynamics. (United States)

    Lauro Grotto, Rosapia; Guazzini, Andrea; Bagnoli, Franco


    In his seminal works on group dynamics Bion defined a specific therapeutic setting allowing psychoanalytic observations on group phenomena. In describing the setting he proposed that the group was where his voice arrived. This physical limit was later made operative by assuming that the natural dimension of a therapeutic group is around 12 people. Bion introduced a theory of the group aspects of the mind in which proto-mental individual states spontaneously evolve into shared psychological states that are characterized by a series of features: (1) they emerge as a consequence of the natural tendency of (both conscious and unconscious) emotions to combine into structured group patterns; (2) they have a certain degree of stability in time; (3) they tend to alternate so that the dissolution of one is rapidly followed by the emergence of another; (4) they can be described in qualitative terms according to the nature of the emotional mix that dominates the state, in structural terms by a kind of typical "leadership" pattern, and in "cognitive" terms by a set of implicit expectations that are helpful in explaining the group behavior (i.e., the group behaves "as if" it was assuming that). Here we adopt a formal approach derived from Socio-physics in order to explore some of the structural and dynamic properties of this small group dynamics. We will described data from an analytic DS model simulating small group interactions of agents endowed with a very simplified emotional and cognitive dynamic in order to assess the following main points: (1) are metastable collective states allowed to emerge in the model and if so, under which conditions in the parameter space? (2) can these states be differentiated in structural terms? (3) to what extent are the emergent dynamic features of the systems dependent of the system size? We will finally discuss possible future applications of the quantitative descriptions of the interaction structure in the small group clinical setting.

  3. The Importance of Forming a Work Group in Small Group Teaching. (United States)

    Ojanen, Sinikka; Keski-Luopa, Leila

    This article discusses the themes of individual and group processes, on the conscious level, as well as the main purpose of a work group, and asserts that psychoanalytical theory and knowledge are a tool for educators. The two problems studied are motivating student teachers to creative action within the small group structure and dealing with…

  4. Dynamical networks of influence in small group discussions. (United States)

    Moussaïd, Mehdi; Noriega Campero, Alejandro; Almaatouq, Abdullah


    In many domains of life, business and management, numerous problems are addressed by small groups of individuals engaged in face-to-face discussions. While research in social psychology has a long history of studying the determinants of small group performances, the internal dynamics that govern a group discussion are not yet well understood. Here, we rely on computational methods based on network analyses and opinion dynamics to describe how individuals influence each other during a group discussion. We consider the situation in which a small group of three individuals engages in a discussion to solve an estimation task. We propose a model describing how group members gradually influence each other and revise their judgments over the course of the discussion. The main component of the model is an influence network-a weighted, directed graph that determines the extent to which individuals influence each other during the discussion. In simulations, we first study the optimal structure of the influence network that yields the best group performances. Then, we implement a social learning process by which individuals adapt to the past performance of their peers, thereby affecting the structure of the influence network in the long run. We explore the mechanisms underlying the emergence of efficient or maladaptive networks and show that the influence network can converge towards the optimal one, but only when individuals exhibit a social discounting bias by downgrading the relative performances of their peers. Finally, we find a late-speaker effect, whereby individuals who speak later in the discussion are perceived more positively in the long run and are thus more influential. The numerous predictions of the model can serve as a basis for future experiments, and this work opens research on small group discussion to computational social sciences.

  5. Commons Dilemma Choices in Small vs. Large Groups. (United States)

    Powers, Richard B.; Boyle, William

    The purpose of the Commons Game is to teach students how social traps work; that is, that short-term individual gain tends to dominate long-term collective gain. Simulations of Commons Dilemma have grown considerably in the last decade; however, the research has used small face-to-face groups to study behavior in the Commons. To compare the…

  6. A Mindfulness Experiential Small Group to Help Students Tolerate Ambiguity (United States)

    Bohecker, Lynn; Vereen, Linwood G.; Wells, Pamela C.; Wathen, Cristen C.


    This study explored the lived experiences of 20 counselors-in-training (CITs) in a mindfulness experiential small group. Using grounded theory, the authors described a 5-dimensional model for navigating ambiguity. Findings suggest mindfulness training provides CITs self-reflection skills and a greater ability to manage cognitive complexity.

  7. The electrocardiogram made (really) easy: Using small-group ...

    African Journals Online (AJOL)

    Medicine designed small-group tutorials using animations and analogies as methods to improve the ECG interpretation skills of students. Objectives. To improve students' ability to interpret ECGs and assess their perceptions of the tutorials. Methods. A questionnaire was administered to 67 final-year medical students after ...

  8. Small arms proliferation. Report on working group 2

    International Nuclear Information System (INIS)


    The working group reported on the proliferation of small arms, light weapons non-lethal weapons, which have traditionally been given little attention in international talks on peace on the contrary to nuclear weapons which have been tested during the Second World War but never used in war later

  9. A DFT study of the interaction of elemental mercury with small neutral and charged silver clusters (United States)

    Sun, Lushi; Zhang, Anchao; Su, Sheng; Wang, Hua; Liu, Junli; Xiang, Jun


    Mercury adsorption on small neutral and charged Ag n clusters has been investigated by using DFT method. The results show that frontier molecular orbital theory is a useful tool to predict the selectivity of Hg adsorption. The binding energies of Hg on the cations are generally greater than those on the corresponding neutral and anionic clusters. NBO analysis indicates the electron flow in the neutral and charged complexes is mainly from the s orbital of Ag to the s orbital of Hg. For neutral and anionic complexes, electron transfer also occurs from p orbital of Hg to s orbital of Ag.

  10. Varying the charge of small cations in liquid water: Structural, transport, and thermodynamical properties (United States)

    Martelli, Fausto; Vuilleumier, Rodolphe; Simonin, Jean-Pierre; Spezia, Riccardo


    In this work, we show how increasing the charge of small cations affects the structural, thermodynamical, and dynamical properties of these ions in liquid water. We have studied the case of lanthanoid and actinoid ions, for which we have recently developed accurate polarizable force fields, and the ionic radius is in the 0.995-1.250 Å range, and explored the valency range from 0 to 4+. We found that the ion charge strongly structures the neighboring water molecules and that, in this range of charges, the hydration enthalpies exhibit a quadratic dependence with respect to the charge, in line with the Born model. The diffusion process follows two main regimes: a hydrodynamical regime for neutral or low charges, and a dielectric friction regime for high charges in which the contraction of the ionic radius along the series of elements causes a decrease of the diffusion coefficient. This latter behavior can be qualitatively described by theoretical models, such as the Zwanzig and the solvated ion models. However, these models need be modified in order to obtain agreement with the observed behavior in the full charge range. We have thus modified the solvated ion model by introducing a dependence of the bare ion radius as a function of the ionic charge. Besides agreement between theory and simulation this modification allows one to obtain an empirical unified model. Thus, by analyzing the contributions to the drag coefficient from the viscous and the dielectric terms, we are able to explain the transition from a regime in which the effect of viscosity dominates to one in which dielectric friction governs the motion of ions with radii of ca. 1 Å.

  11. Preparation of small group constants for calculation of shielding

    International Nuclear Information System (INIS)

    Khokhlov, V.F.; Shejno, I.N.; Tkachev, V.D.


    Studied is the effect of the shielding calculation error connected with neglect of the angular and spatial neutron flux dependences while determining the small-group constants on the basis of the many-group ones. The economical method allowing for dependences is proposed. The spatial dependence is substituted by the average value according to the zones singled out in the limits of the zones of the same content; the angular cross section dependence is substituted by the average values in the half-ranges of the angular variable. To solve the transfer equation the ALGOL-ROSA-M program using the method of characteristic interpolation and trial run method is developed. The program regards correctly for nonscattered and single scattered radiations. Compared are the calculation results of neutron transmission (10.5 MeV-0.01 eV) in the 21-group approximation with the 3-group calculations for water (the layer thickness is 30 cm) and 5-group calculations for heterogeneous shielding of alternating stainless steel layers (3 layers, each of the 16 cm thickness) and graphite layers (2 layers, each of the 20 cm thickness). The analysis shows that the method proposed permits to obtain rather accurate results in the course of preparation of the small-group cross sections, decreasing considerably the number of the groups (from 21 to 3-5) and saving the machine time

  12. Link between hopping models and percolation scaling laws for charge transport in mixtures of small molecules

    Directory of Open Access Journals (Sweden)

    Dong-Gwang Ha


    Full Text Available Mixed host compositions that combine charge transport materials with luminescent dyes offer superior control over exciton formation and charge transport in organic light emitting devices (OLEDs. Two approaches are typically used to optimize the fraction of charge transport materials in a mixed host composition: either an empirical percolative model, or a hopping transport model. We show that these two commonly-employed models are linked by an analytic expression which relates the localization length to the percolation threshold and critical exponent. The relation is confirmed both numerically and experimentally through measurements of the relative conductivity of Tris(4-carbazoyl-9-ylphenylamine (TCTA :1,3-bis(3,5-dipyrid-3-yl-phenylbenzene (BmPyPb mixtures with different concentrations, where the TCTA plays a role as hole conductor and the BmPyPb as hole insulator. The analytic relation may allow the rational design of mixed layers of small molecules for high-performance OLEDs.

  13. Constraints on dark matter particles charged under a hidden gauge group from primordial black holes

    International Nuclear Information System (INIS)

    Dai, De-Chang; Stojkovic, Dejan; Freese, Katherine


    In order to accommodate increasingly tighter observational constraints on dark matter, several models have been proposed recently in which dark matter particles are charged under some hidden gauge group. Hidden gauge charges are invisible for the standard model particles, hence such scenarios are very difficult to constrain directly. However black holes are sensitive to all gauge charges, whether they belong to the standard model or not. Here, we examine the constraints on the possible values of the dark matter particle mass and hidden gauge charge from the evolution of primordial black holes. We find that the existence of the primordial black holes with reasonable mass is incompatible with dark matter particles whose charge to mass ratio is of the order of one. For dark matter particles whose charge to mass ratio is much less than one, we are able to exclude only heavy dark matter in the mass range of 10 11 GeV–10 16 GeV. Finally, for dark matter particles whose charge to mass ratio is much greater than one, there are no useful limits coming from primordial black holes

  14. Nanoparticle charge control in nonpolar liquids: insights from small-angle neutron scattering and microelectrophoresis. (United States)

    Kemp, Roger; Sanchez, Rodrigo; Mutch, Kevin J; Bartlett, Paul


    Electrostatic forces are typically produced in low polarity solvents by the addition of surfactants or charge-control additives. Although widely used, there is no consensus on the mechanism by which surfactants control the level of particle charge. We report an investigation using highly sensitive, single particle optical microelectrophoresis measurements combined with a small-angle neutron scattering study to establish the mechanism of charging by the surfactant AOT in the nonpolar solvent n-dodecane. We show that polymer-grafted particles with no chemically bound surface charges only charge above the critical micellar concentration of the surfactant. The surface potential increases gradually with increasing surfactant concentration c, before finally saturating at high c. The increase in the surface potential is correlated to the amount of surfactant adsorbed onto the surface of the particle. Using deuterated AOT and contrast variation techniques, we demonstrate that the surfactant is adsorbed within the polymer layer surrounding the particle core, probably as individual molecules rather than surfactant aggregates. A simple thermodynamic model accounts for the concentration dependence of the observed surface potential.

  15. Using social media to support small group learning. (United States)

    Cole, Duncan; Rengasamy, Emma; Batchelor, Shafqat; Pope, Charles; Riley, Stephen; Cunningham, Anne Marie


    Medical curricula are increasingly using small group learning and less didactic lecture-based teaching. This creates new challenges and opportunities in how students are best supported with information technology. We explored how university-supported and external social media could support collaborative small group working on our new undergraduate medical curriculum. We made available a curation platform ( and a wiki within our virtual learning environment as part of year 1 Case-Based Learning, and did not discourage the use of other tools such as Facebook. We undertook student surveys to capture perceptions of the tools and information on how they were used, and employed software user metrics to explore the extent to which they were used during the year. Student groups developed a preferred way of working early in the course. Most groups used Facebook to facilitate communication within the group, and to host documents and notes. There were more barriers to using the wiki and curation platform, although some groups did make extensive use of them. Staff engagement was variable, with some tutors reviewing the content posted on the wiki and curation platform in face-to-face sessions, but not outside these times. A small number of staff posted resources and reviewed student posts on the curation platform. Optimum use of these tools depends on sufficient training of both staff and students, and an opportunity to practice using them, with ongoing support. The platforms can all support collaborative learning, and may help develop digital literacy, critical appraisal skills, and awareness of wider health issues in society.

  16. Using social media to support small group learning

    Directory of Open Access Journals (Sweden)

    Duncan Cole


    Full Text Available Abstract Background Medical curricula are increasingly using small group learning and less didactic lecture-based teaching. This creates new challenges and opportunities in how students are best supported with information technology. We explored how university-supported and external social media could support collaborative small group working on our new undergraduate medical curriculum. Methods We made available a curation platform ( and a wiki within our virtual learning environment as part of year 1 Case-Based Learning, and did not discourage the use of other tools such as Facebook. We undertook student surveys to capture perceptions of the tools and information on how they were used, and employed software user metrics to explore the extent to which they were used during the year. Results Student groups developed a preferred way of working early in the course. Most groups used Facebook to facilitate communication within the group, and to host documents and notes. There were more barriers to using the wiki and curation platform, although some groups did make extensive use of them. Staff engagement was variable, with some tutors reviewing the content posted on the wiki and curation platform in face-to-face sessions, but not outside these times. A small number of staff posted resources and reviewed student posts on the curation platform. Conclusions Optimum use of these tools depends on sufficient training of both staff and students, and an opportunity to practice using them, with ongoing support. The platforms can all support collaborative learning, and may help develop digital literacy, critical appraisal skills, and awareness of wider health issues in society.

  17. Influence of capture to excited states of multiply charged ion beams colliding with small molecules

    International Nuclear Information System (INIS)

    Montenegro, P; Monti, J M; Fojón, O A; Hanssen, J; Rivarola, R D


    Electron capture by multiply charged ions impacting on small molecules is theoretically investigated. Particular attention is paid to the case of biological targets. The interest is focused on the importance of the transition to excited final states which can play a dominant role on the total capture cross sections. Projectiles at intermediate and high collision energies are considered. Comparison with existing experimental data is shown. (paper)

  18. Concerning the Charging of an Exploration Craft on and near a Small Asteroid (United States)

    Jackson, T. L.; Zimmerman, M. I.; Farrell, W. M.


    Introduction: An object immersed in an airless plasma environment will experience a natural process of surface charging in order to acheieve current balance, or zero net electric current to the object. It has been shown in recent computer simulations that the small-body plasma environment is very complex [1], considering effects of photoemission, topography, and formation of a plasma wake. For this work we consider an exploration craft (or astronaut) immersed within a plasma environment near an asteroid, which exhibits widely varying solar wind and photoelectric particle fluxes and continuously evolving illumination conditions. Objective: We aim to determine how an explo-ration craft or astronaut suit accumulates charge while located in the "nightside" asteroid wake where the particle fluxes are reduced, and in the dayside near-surface photoelectron sheath, by combining an object charging model [2] with kinetic simulations of a near-asteroid plasma environment [1]. We consider an astronaut floating near the asteroid while not in contact with the surface, as well as an astronaut moving along the surface using their hands/gloves to crawl along. Results: The modeling results suggest that remediation of triboelectric charge via accumulation of plasma currents is an important factor to consider when designing future NEA mission infrastructure, especially if repeated and frequent contact with the surface is planned. In shadowed regions such as the location shown in Fig. 1a, the plasma currents are so low (and the effective charge-remediation timescale so long, e.g. minutes to hours) that repeated contact with the surface tribocharges the glove in an uncontrollable fashion, as shown for two representative electron temperatures in Fig. 2a. The resulting buildup of significant negative charge would eventually initiate some other "current of last resort" [4] such as transport of positively-charged dust, field-emission from the glove, or significant alteration of

  19. Facilitating small groups: how to encourage student learning. (United States)

    Kitchen, Mark


    Many clinicians are involved in medical education, with small group teaching (SGT) forming a significant part of their work. Most facilitate these sessions by experience and common sense: less than one-third of them have received formal training in SGT. Evidence suggests small group productivity depends on good facilitation rather than on topic knowledge. Applying the fundamental concepts of SGT will lead to improvements in the quality of clinicians' teaching and in student learning. Good SGT creates the perfect environment for learning and discussion, without the need for didactic teaching. SGT emphasises the role of students in sharing and discussing their ideas in a safe learning environment, without domination by the tutor. This article provides clinicians with basic requirements for effective session design and planning, explains how to encourage student participation, how to manage students as a group, how to manage student learning, and how to recognise and deal with problems. Active facilitation and group management is the key to success in SGT, and consequently better learning outcomes. Improving the facilitation skills of clinical teachers makes teaching more effective, stimulating, and enjoyable for both tutors and students. © Blackwell Publishing Ltd 2012.

  20. Volunteer patients and small groups contribute to abdominal examination's success

    Directory of Open Access Journals (Sweden)

    Shields HM


    Full Text Available Helen M Shields,1 Nielsen Q Fernandez-Becker,2 Sarah N Flier,2 Byron P Vaughn,2 Melissa H Tukey,2 Stephen R Pelletier,3 Douglas A Horst2 1Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, 2Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, 3Center for Evaluation, Harvard Medical School, Boston, MA, USA Background: Prior to 2007, we taught the abdominal examination in a hospital based group to 40 students, at one hospital. We used volunteer patients, small groups, repetition, and required faculty development sessions. In 2007, our medical school changed its “Introduction to Physical Examination” session so that the entire class was to be taught in a geographically central session. Our hospital was selected to lead the abdominal examination portion of the session. Aim: Our aim was to answer three questions. First, could we quadruple the recruitment of volunteer patients, and faculty? Second, was it volunteer patients, small groups, repetition, or faculty training that was most valued by the students? Third, would volunteer patients and/or faculty agree to participate a second time? Methods: A total of 43-46 patients and 43-46 faculty were recruited and 43-46 examining rooms were obtained for each of the 5 years of this study. Teachers were required to attend a 1-hour faculty development session. The class of about 170 students was divided into 43–46 groups each year. The teacher demonstrated the abdominal examination and each student practiced the examination on another student. Each student then repeated the full abdominal examination on a volunteer patient. Results: Over the 5-year time period (2008–2012, the abdominal examination ranked first among all organ systems’ “Introductory Sessions”. The abdominal examination ratings had the best mean score (1.35 on a Likert scale where 1 is excellent and 5 is poor. The students gave the most

  1. In Vitro Assessment of Small Charged Pharmaceutical Aerosols in a Model of a Ventilated Neonate. (United States)

    Holbrook, Landon; Hindle, Michael; Longest, P Worth


    Aerosolized medications may benefit infants receiving mechanical ventilation; however, the lung delivery efficiency of these aerosols is unacceptably low. In vitro experiments were conducted to evaluate aerosol delivery through conventional and modified ventilation systems to the end of a 3mm endotracheal tube (ETT) under steady state and realistic cyclic flow conditions. System modifications were employed to investigate the use of small charged particles and included streamlined components, a reduction in nebulizer liquid flow rate, synchronization with inspiration, and implementation of a previously designed low-flow induction charger (LF-IC), which was further modified in this study. Cyclic flow experiments implemented a modern ventilator with bias airflow and an inline flow meter, both of which are frequently excluded from in vitro tests but included in clinical practice. The modified LF-IC system demonstrated superior delivery efficiency to the end of the ETT (34%) compared with the commercial system (~1.3%) operating under cyclic ventilation conditions. These findings indicate that commercial systems still provide very low lung delivery efficiencies despite decades of innovation. In contrast, the modified system increased dose delivery to the end of the ETT by 26-fold. Despite initial concerns, the charged aerosol could be efficiently delivered through the small diameter ETT and reach the lungs. Future studies will be required to determine if the applied particle charge can eliminate expected high exhalation aerosol loss and will require the development of a realistic lung model.

  2. Emergency Medicine Curriculum: Complications of Pregnancy Small Group Module

    Directory of Open Access Journals (Sweden)

    Linda L Herman


    Full Text Available Audience: This curriculum, created and implemented at Kaweah Delta HCD emergency medicine program, was designed to educate our emergency medicine (EM residents, PGY-1 to PGY-3, as well as medical students and attending physicians. Introduction: Obstetrical (OB emergencies pose a unique challenge to the EM physician. Given the relative rarity of these presentations within the Emergency Department (ED, it is important that residents are educated in a comprehensive manner to ensure understanding and retention.1 The exact prevalence of emergency department (ED visits that are associated with complications of pregnancy is unknown, but they are likely a sizeable portion of the patient population of the ED. Also, many hospitals in rural areas have closed their labor and delivery units due to higher operating costs and lack of available medical personnel.2 New models of high-quality teaching that ensure retention of clinically rare, but critical presentations are required. There is a body of research that suggests a small-group discussion model rather than traditional lecture-based content may improve learner engagement and retention. This model encourages active learning, which requires simultaneous instructor and learner engagement.3, 4, 5, 6, 7 Studies have revealed that the application of knowledge through case studies, personal interaction with content experts, and integrated questions are effective learning strategies for emergency medicine.3 The small group discussion classroom is facilitated by content experts with personal experience in the topic at hand. Objectives: We aim to teach the presentation and management of pregnancy complications through interactive teaching during small group discussions concerning patient cases. This curriculum utilizes resources chosen by education faculty, study questions, actual experience, and small group discussions in place of a traditional lecture-based format. In doing so, a goal of the curriculum is to

  3. Practice-based small group learning in GP specialty training. (United States)

    Hesselgreaves, Hannah; MacVicar, Ronald


    Practice-based small group learning (PBSGL) is an approach to continuing professional development (CPD) for general practitioners (GPs) that originated in Canada. It involves small groups of GPs who work through clinical modules. PBSGL is now an established method of learning in Scotland, found to be effective in GP, practice nurse and multi-professional cohorts. However, the effectiveness of PBSGL has not been examined in GP specialty training, where it is becoming widely employed. This research aimed to explore GP Specialty Trainees' (GPSTs') perspectives of the impact of PBSGL on curriculum needs, preparation for independent practice, and facilitator learning. To avoid the risk of extrapolating assumptions from others who have used PBSGL as a learning strategy, this study adopted a qualitative approach, and conducted one-to-one interviews with 16 GPSTs from a range of Scottish deaneries and stages in training. Data took the form of verbatim transcripts, and the constant comparative technique from grounded theory was used to analyse the data, through the establishment of codes and categories. Findings were arranged in four main areas: • learning as a group was appreciated at this career stage, and group membership should consist of trainees at a similar career stage, as this supports psychological safety • PBSGL helped in locating a 'one best way' for future care planning, but was also used to find alternatives to trainees' current approaches • discussion during PBSGL helped GPSTs devise plans for how they would handle patients in the future • some facilitators moderated their involvement for the perceived benefit of the group. Learning is experienced in a very unique way for GPSTs, and the views of the cohort are formed on the basis of the delicate stage in their career. Aiding the transition from structured education into independent practice is a more immediate need for GPSTs than curriculum needs.

  4. The cyclopentyl group, as a small but bulky terminal group, allows rapid and efficient active transport. (United States)

    Nishiyama, Junya; Makita, Yoshimasa; Kihara, Nobuhiro


    Secondary ammonium salts bearing a cyclopentyl terminal group rapidly formed pseudorotaxane with 1.5 equiv of DB24C8. Acylation of the pseudorotaxane with 50 equiv of benzoyl chloride in the presence of 50 equiv of triethylamine in toluene afforded rotaxane, the product of active transport, in 95% yield. The cyclopentyl group is small enough to allow rapid formation of pseudorotaxane, and bulky enough to facilitate the quantitative active transport by steric repulsion.

  5. A Small Angle Neutron Scattering Study of Cylindrical nanoparticle with Controlled Surface Charge Density

    International Nuclear Information System (INIS)

    Kim, Tae-Hwan; Choi, Sung-Min; Kline, Steven R.


    Surfactant molecules in aqueous solution self assemble into various micellar structures such as sphere, rod, vesicle, and lamellar, above critical micelle concentration (CMC). Self-assembled surfactants systems, therefore, have been very popular as templates for preparing various nanostructured materials. Due to their dynamic nature, however, micellar structures are very susceptible to solution conditions such as temperature, concentration, pH and pressure, limiting their applications. In this study, we have developed rigid rod-like nanoparticles with controlled surface charge density by the free radical polymerization of cationic surfactants with polymerizable counterions, cetyltrimethylammonium 4- vinylbenzoate (CTVB), with varying concentration of sodium styrenesulfonate (NaSS). The structure and surface charge density of the nanoparticles were characterized by small angle neutron scattering (SANS) and zeta potential measurements

  6. Task Type and Group Motivation: Implications for a Behavioral Approach to Leadership in Small Groups. (United States)

    Latham, Van M.


    Discusses a theory of leadership effectiveness in small discussion/decision making groups developed to facilitate discussion and goal efficacy. Develops four leadership styles (coordinator, inventor, enthusiast, and director) focusing on two critical questions the leader must address. Discusses implications of the model for leadership training and…

  7. The role of electrostatic charging of small and intermediate sized bodies in the solar system

    International Nuclear Information System (INIS)

    Mendis, D.A.


    The role of electrostatic charging of small and intermediate sized bodies in the solar system is reviewed. These bodies include planetary, interplanetary and cometary dust as well as cometary nuclei (at large heliocentric distances), asteroids and the larger bodies in the Saturnian ring system. While this charging has both physical and dynamical consequences for the small dust grains, it has only physical consequences for the larger bodies. The main physical consequences for the small grains are electrostatic erosion (''chipping'') and disruption, whereas for the larger bodies they include electrostatic levitation and blow-off of fine loose dust from their surfaces. A large variety of solar system phenomena, recently observed by the Pioneer and Voyager deep space probes as well as the HEOS-2 earth satellite, are explained in terms of these processes. Certain peculiar features observed in the dust tails of comets as well as the spatial orientation of the zodiacal dust cloud may also be explained along these lines. The possible electrostatic erosion of the dust mantles of new comets as well as the electrostatic 'polishing' of the smaller asteroids are also discussed. (Auth.)

  8. Opinion dynamics within a virtual small group: the stubbornness effect (United States)

    Guazzini, Andrea; Cini, Alessandro; Bagnoli, Franco; Ramasco, José


    The modeling of opinion dynamics is social systems has attracted a good deal of attention in the last decade. Even though based on intuition and observation, the mechanisms behind many of these models need solid empirical grounding. In this work, we investigate the relation among subjective variables (such as the personality), the dynamics of the affinity network dynamics, the communication patterns emerging throughout the social interactions and the opinions dynamics in a series of experiments with five small groups of ten people each. In order to ignite the discussion, the polemic topic of animal experimentation was proposed. The groups essentially polarized in two factions with a set of stubborn individuals (those not changing their opinions in time) playing the role of anchors. Our results suggest that the different layers present in the group dynamics (i.e., individual level, group dynamics and meso-communication) are deeply intermingled, specifically the stubbornness effect appears to be related to the dynamical features of the network topologies, and only in an undirected way to the personality of the participants.

  9. Opinion dynamics within a virtual small group: the stubbornness effect

    Directory of Open Access Journals (Sweden)

    Andrea eGuazzini


    Full Text Available The modeling of opinion dynamics is social systems has attracted a good deal of attention in the last decade. Even though based on intuition and observation, the mechanisms behind many of these models need solid empirical grounding. In this work, we investigate the relation among subjective variables (such as the personality, the dynamics of the affinity network dynamics, the communication patterns emerging throughout the social interactions and the opinions dynamics in a series of experiments with five small groups of ten people each. In order to ignite the discussion, the polemic topic of animal experimentation was proposed. The groups essentially polarized in two factions with a set of stubborn individuals (those not changing their opinions in time playing the role of anchors. Our results suggest that the different layers present in the group dynamics (i.e., individual level, group dynamics and meso-communication are deeply intermingled, specifically the stubbornness effect appears to be related to the dynamical features of the network topologies, and only in an undirected way to the personality of the participants.


    Directory of Open Access Journals (Sweden)

    Radka Borůvková


    Full Text Available Building relationships in the classroom is an essential part of any teacher's career. Having healthy teacher-to-learner and learner-to-learner relationships is an effective way to help prevent pedagogical failure, social conflict and quarrelsome behavior. Many strategies are available that can be used to achieve good long-lasting relationships in the classroom setting. Successful teachers’ pedagogical work in the classroom requires detailed knowledge of learners’ relationships. Good understanding of the relationships is necessary, especially in the case of teenagers’ class. This sensitive period of adolescence demands attention of all teachers who should deal with the problems of their learners. Special care should be focused on children that are out of their classmates’ interest (so called isolated learners or isolates in such class and on possibilities to integrate them into the class. Natural idea how to do it is that of using some modern non-traditional teaching/learning methods, especially the methods based on work in small groups involving learners’ cooperation. Small group education (especially problem-based learning, project-based learning, cooperative learning, collaborative learning or inquire-based learning as one of these methods involves a high degree of interaction. The effectiveness of learning groups is determined by the extent to which the interaction enables members to clarify their own understanding, build upon each other's contributions, sift out meanings, ask and answer questions. An influence of this kind of methods (especially cooperative learning (CL on learners’ relationships was a subject of the further described research. Within the small group education, students work with their classmates to solve complex and authentic problems that help develop content knowledge as well as problem-solving, reasoning, communication, and self-assessment skills. The aim of the research was to answer the question: Can the

  11. Density functional study of the interaction of carbon monoxide with small neutral and charged silver clusters. (United States)

    Zhou, Jia; Li, Zhen-Hua; Wang, Wen-Ning; Fan, Kang-Nian


    CO adsorption on small neutral, anionic, and cationic silver clusters Ag(n) (n = 1-7) has been studied with use of the PW91PW91 density functional theory (DFT) method. The adsorption of CO on-top site, among various possible sites, is energetically preferred irrespective of the charge state of the silver cluster. The cationic silver clusters generally have a greater tendency to adsorb CO than the anionic and neutral silver ones, except for n = 3 and 4, and the binding energies reach a local minimum at n = 5. The binding energies on the neutral clusters, instead, reach a local maximum at n = 3, which is about 0.87 eV, probably large enough to be captured in the experiments. Binding of CO to the silver clusters is generally weaker than that to the copper and gold counterparts at the same size and charge state. This is due to the weaker orbital interaction between silver and CO, which is caused by the larger atomic radius of the silver atom. In contrast, Au atoms with a larger nuclear charge but a similar atomic radius to silver owing to the lanthanide contraction are able to have a stronger interaction with CO.

  12. Bond-forming reactions of small triply charged cations with neutral molecules. (United States)

    Fletcher, James D; Parkes, Michael A; Price, Stephen D


    Time-of-flight mass spectrometry reveals that atomic and small molecular triply charged cations exhibit extensive bond-forming chemistry, following gas-phase collisions with neutral molecules. These experiments show that at collision energies of a few eV, I(3+) reacts with a variety of small molecules to generate molecular monocations and molecular dications containing iodine. Xe(3+) and CS2(3+) react in a similar manner to I(3+), undergoing bond-forming reactions with neutrals. A simple model, involving relative product energetics and electrostatic interaction potentials, is used to account for the observed reactivity. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. A small-group approach to teaching family medicine. (United States)

    Lennox, L; Devieux, J; Huff, F; Barker, P; Arradondo, J E; Devieux, R


    The authors describe a method for teaching preclinical medical students some important family medicine concepts utilizing a seminar format which allows for improved student-teacher interaction and individualization of material. These seminars, on family health behavior, compliance, behavioral interventions for life-style change, and managing stress, were designed to encourage freshman medical students to understand and apply concepts concerning health behavior and attitudes, both personally and professionally. The format of these sessions included the use of self-assessment instruments, discussion, role play, and case studies. Results of student evaluations indicate they perceived the seminars positively. Specific areas of positive value included the content and small-group related processes. The seminars also provided data useful for developing programs for students.

  14. Exploratory study of nuclear reaction data utility framework of Japan charged particle reaction data group (JCPRG)

    Energy Technology Data Exchange (ETDEWEB)

    Masui, Hiroshi; Ohnishi, Akira; Kato, Kiyoshi [Hokkaido Univ., Graduate School of Science, Sapporo, Hokkaido (Japan); Ohbayasi, Yosihide [Hokkaido Univ., Meme Media Lab., Sapporo, Hokkaido (Japan); Aoyama, Shigeyoshi [Kitami Institute of Technology, Information Processing Center, Kitami, Hokkaido (Japan); Chiba, Masaki [Sapporo Gakuin Univ., Faculty of Social Information, Ebetsu, Hokkaido (Japan)


    Compilation, evaluation and dissemination are essential pieces of work for the nuclear data activities. We, Japan charged particle data group, have researched the utility framework for the nuclear reaction data on the basis of recent progress of computer and network technologies. These technologies will be not only for the data dissemination but for the compilation and evaluation assistance among the many corresponding researchers of all over the world. In this paper, current progress of our research and development is shown. (author)

  15. Exploratory study of nuclear reaction data utility framework of Japan charged particle reaction data group (JCPRG)

    International Nuclear Information System (INIS)

    Masui, Hiroshi; Ohnishi, Akira; Kato, Kiyoshi; Ohbayasi, Yosihide; Aoyama, Shigeyoshi; Chiba, Masaki


    Compilation, evaluation and dissemination are essential pieces of work for the nuclear data activities. We, Japan charged particle data group, have researched the utility framework for the nuclear reaction data on the basis of recent progress of computer and network technologies. These technologies will be not only for the data dissemination but for the compilation and evaluation assistance among the many corresponding researchers of all over the world. In this paper, current progress of our research and development is shown. (author)

  16. Students' attitudes to small-group work in community health. (United States)

    Whittaker, D E; Hoffman, M


    To encourage fourth-year medical students to review their ethnocentric attitudes to the politicized issues of population and undernutrition in South Africa, small-group work (SGW) was introduced during a month's teaching in community health at the University of Cape Town. We tested several formats for these sessions and chose one which seemed effective. This study examined the remaining students' attitudes to SGW as a means of briefly examining complex emotive topics. Sixty-nine students of a class of 168 were asked to complete a Likert questionnaire on their attitudes to SGW. Fifty-five students (79.7%) agreed that group work had allowed them to engage the topics briefly but usefully and 62 (90%) thought that the topics lent themselves to SGW. While 52 (75.3%) were not confused, 5 (7.2%) were confused by SGW. Thirty-nine students (56.5%) preferred lectures, tutorials or seminars to SGW. Thirty-seven students (53.6%) needed more fact to benefit fully from the SGW. Students found SGW appropriate for briefly examining these topics but wanted more fact to benefit fully from the sessions. The survey yielded valuable feedback from students on SGW as a means of addressing controversial and attitude-laden issues of central importance to the delivery of effective health care in Southern Africa.

  17. Using Telestrations™ to Illustrate Small Group Communication Principles (United States)

    Fedesco, Heather Noel


    This single class activity described here: (1) illustrates the importance of interdependence in groups; (2) can be used to measure group productivity and performance; (3) can encourage groups to engage in group learning; and (4) can facilitate group cohesion for newly formed groups. Students will be working in groups for the majority of their…

  18. c-function and central charge of the sine-Gordon model from the non-perturbative renormalization group flow

    Directory of Open Access Journals (Sweden)

    V. Bacsó


    Full Text Available In this paper we study the c-function of the sine-Gordon model taking explicitly into account the periodicity of the interaction potential. The integration of the c-function along trajectories of the non-perturbative renormalization group flow gives access to the central charges of the model in the fixed points. The results at vanishing frequency β2, where the periodicity does not play a role, are retrieved and the independence on the cutoff regulator for small frequencies is discussed. Our findings show that the central charge obtained integrating the trajectories starting from the repulsive low-frequencies fixed points (β2<8π to the infra-red limit is in good quantitative agreement with the expected Δc=1 result. The behavior of the c-function in the other parts of the flow diagram is also discussed. Finally, we point out that including also higher harmonics in the renormalization group treatment at the level of local potential approximation is not sufficient to give reasonable results, even if the periodicity is taken into account. Rather, incorporating the wave-function renormalization (i.e. going beyond local potential approximation is crucial to get sensible results even when a single frequency is used.

  19. Comparative study of a small size wind generation system efficiency for battery charging

    Directory of Open Access Journals (Sweden)

    Mayouf Messaoud


    Full Text Available This paper presents an energetic comparison between two control strategies of a small size wind generation system for battery charging. The output voltage of the direct drive PMSG is connected to the battery through a switch mode rectifier. A DC-DC boost converter is used to regulate the battery bank current in order to achieve maximum power from the wind. A maximum powertracking algorithm calculates the current command that corresponds to maximum power output of the turbine. The DC-DC converter uses this current to calculate the duty cycle witch is necessary to control the pulse width modulated (PWM active switching device (IGPT. The system overview and modeling are presented including characteristics of wind turbine, generator, batteries, power converter, control system, and supervisory system. A simulation of the system is performed using MATLAB/SIMULINK.

  20. Anomalous small-angle X-ray scattering from charged soft matter (United States)

    Sztucki, M.; Di Cola, E.; Narayanan, T.


    A review of recent applications of Anomalous Small-Angle X-ray Scattering (ASAXS) to charged soft matter systems is presented. Although the potential of ASAXS was realized in the eighties [1], applications to soft matter systems became feasible in recent years thanks to the technical developments at the synchrotron sources. Examples include both stiff chain and flexible polyelectrolytes, colloidal brush-like polyelectrolytes, DNA, RNA, and polysaccharides where the counterion profile could be determined with high precision and compared with theoretical models. In addition, ASAXS has also been found useful for microstructure characterization in soft materials. Finally, the present capability for ASAXS studies is illustrated by an example involving a surfactant micellar system.

  1. Characteristics of the groups of charged particles in bar pp,pp and K-p interactions at 32 GeV/c

    International Nuclear Information System (INIS)

    Bogolubsky, M.Yu.; Levitsky, M.S.; Maksimov, V.V.


    In the clan model, a method is developed for determining the following characteristics of the groups of charged particles: group multiplicity in an interval, particle multiplicity in a group, and width distribution of groups. Distribution densities are obtained for particles originating from clans produced at a given rapidity point with given width in bar pp, K - p, and pp interactions at 32 GeV/c. It is shown that the differences in the rate of growth of factorial moments in bar pp and K - p interactions are due to a difference in the relative contributions of small-width clans. 12 refs., 13 figs., 2 tabs

  2. Quasinormal modes of a massless charged scalar field on a small Reissner-Nordstroem-anti-de Sitter black hole

    International Nuclear Information System (INIS)

    Uchikata, Nami; Yoshida, Shijun


    We investigate quasinormal modes of a massless charged scalar field on a small Reissner-Nordstroem-anti-de Sitter (RN-AdS) black hole both with analytical and numerical approaches. In the analytical approach, by using the small black hole approximation (r + + /L→0, where r + and L stand for the black hole event horizon radius and the AdS scale, respectively. We then show that the small RN-AdS black hole is unstable if its quasinormal modes satisfy the superradiance condition and that the instability condition of the RN-AdS black hole in the limit of r + /L→0 is given by Q>(3/eL)Q c , where Q, Q c , and e are the charge of the black hole, the critical (maximum) charge of the black hole, and the charge of the scalar field, respectively. In the numerical approach, we calculate the quasinormal modes for the small RN-AdS black holes with r + + =0.2L, 0.1L, and 0.01L become unstable against scalar perturbations with eL=4 when the charge of the black hole satisfies Q > or approx. 0.8Q c , 0.78Q c , and 0.76Q c , respectively.

  3. Small scale density variations of electrons and charged particles in the vicinity of polar mesosphere summer echoes

    Directory of Open Access Journals (Sweden)

    M. Rapp


    Full Text Available We present small scale variations of electron number densities and particle charge number densities measured in situ in the presence of polar mesosphere summer echoes. It turns out that the small scale fluctuations of electrons and negatively charged particles show a strong anticorrelation down to the smallest scales observed. Comparing these small scale structures with the simultaneously measured radar signal to noise profile, we find that the radar profile is well described by the power spectral density of both electrons and charged particles at the radar half wavelength (=the Bragg scale. Finally, we consider the shape of the power spectra of the observed plasma fluctuations and find that both charged particles and electrons show spectra that can be explained in terms of either neutral air turbulence acting on the distribution of a low diffusivity tracer or the fossil remnants of a formerly active turbulent region. All these results are consistent with the theoretical ideas by Rapp and Lübken (2003 suggesting that PMSE can be explained by a combination of active and fossil neutral air turbulence acting on the large and heavy charged aerosol particles which are subsequently mirrored in the electron number density distribution that becomes visible to a VHF radar when small scale fluctuations are present.

  4. Collective Motivation Beliefs of Early Adolescents Working in Small Groups (United States)

    Klassen, Robert M.; Krawchuk, Lindsey L.


    This study examined collective efficacy, group cohesion, and group performance in 125 randomly assigned groups of older (mean age 13.45 years) and younger (mean age 11.41 years) early adolescents working on three cooperative tasks. Collective motivation significantly predicted performance, even after controlling for past performance and…

  5. Internal configuration and electric potential in planar negatively charged lipid head group region in contact with ionic solution. (United States)

    Lebar, Alenka Maček; Velikonja, Aljaž; Kramar, Peter; Iglič, Aleš


    The lipid bilayer composed of negatively charged lipid 1-palmitoyl-3-oleoyl-sn-glycero-3-phosphatidylserine (POPS) in contact with an aqueous solution of monovalent salt ions was studied theoretically by using the mean-field modified Langevin-Poisson-Boltzmann (MLPB) model. The MLPB results were tested by using molecular dynamic (MD) simulations. In the MLPB model the charge distribution of POPS head groups is theoretically described by the negatively charged surface which accounts for negatively charged phosphate groups, while the positively charged amino groups and negatively charged carboxylate groups are assumed to be fixed on the rod-like structures with rotational degree of freedom. The spatial variation of relative permittivity, which is not considered in the well-known Gouy-Chapman (GC) model or in MD simulations, is thoroughly derived within a strict statistical mechanical approach. Therefore, the spatial dependence and magnitude of electric potential within the lipid head group region and its close vicinity are considerably different in the MLPB model from the GC model. The influence of the bulk salt concentration and temperature on the number density profiles of counter-ions and co-ions in the lipid head group region and aqueous solution along with the probability density function for the lipid head group orientation angle was compared and found to be in qualitative agreement in the MLPB and MD models. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Teaching as Interaction: Challenges in Transitioning Teachers' Instruction to Small Groups (United States)

    Wyatt, Tasha; Chapman-DeSousa, Brook


    Although small group instruction is often endorsed in teaching young children, teachers are rarely given explicit instruction on how to move instruction into small groups where effective adult-child interactions can take place. This study examines how 14 early childhood educators transitioned their instruction from whole to small group teaching…

  7. Small groups, contexts, and civic engagement: A multilevel analysis of United States Congregational Life Survey data. (United States)

    Whitehead, Andrew L; Stroope, Samuel


    Prior research suggests that church-goers are more civically engaged than their non-church-going counterparts. Little is known, however, about how the popular phenomenon of small groups factors into this equation. In the present study, we examine relationships between small group participation at individual and congregation levels and civic engagement. Using multilevel modeling and national data on congregations and individuals from the U.S. Congregational Life Study (n=82,044), we find that: (1) individual-level small group involvement is associated with four measures of civic engagement; (2) congregation-level small group participation is associated with both lower and higher civic engagement in the case of two outcomes; and (3) in the case of three civic outcomes, congregation-level small group participation moderates individual-level small group involvement such that small group members' civic activity more closely resembles the lower civic engagement of small group nonparticipants. In the case of one civic outcome, at high levels of overall small group participation, small group members' civic engagement drops below that of small group nonparticipants. Explanations for these findings, including a "crowding out" effect, are examined including their complex implications for debates regarding small groups, religious involvement, and civic engagement. Copyright © 2014 Elsevier Inc. All rights reserved.

  8. Leader Communication Style: Effects on Members of Small Groups. (United States)

    Barlow, Sally; And Others


    Determined effects of different leader verbal styles on group members. Results indicated leader verbal style is a factor influencing communication style of members and that it affects members' perceptions of leader orientation; however, it does not affect members' satisfaction with leaders, nor the self-concept of group members. (Author/RC)

  9. Compact stars with a small electric charge: the limiting radius to mass relation and the maximum mass for incompressible matter

    International Nuclear Information System (INIS)

    Lemos, Jose P.S.; Lopes, Francisco J.; Quinta, Goncalo; Zanchin, Vilson T.


    One of the stiffest equations of state for matter in a compact star is constant energy density and this generates the interior Schwarzschild radius to mass relation and the Misner maximum mass for relativistic compact stars. If dark matter populates the interior of stars, and this matter is supersymmetric or of some other type, some of it possessing a tiny electric charge, there is the possibility that highly compact stars can trap a small but non-negligible electric charge. In this case the radius to mass relation for such compact stars should get modifications. We use an analytical scheme to investigate the limiting radius to mass relation and the maximum mass of relativistic stars made of an incompressible fluid with a small electric charge. The investigation is carried out by using the hydrostatic equilibrium equation, i.e., the Tolman-Oppenheimer-Volkoff (TOV) equation, together with the other equations of structure, with the further hypothesis that the charge distribution is proportional to the energy density. The approach relies on Volkoff and Misner's method to solve the TOV equation. For zero charge one gets the interior Schwarzschild limit, and supposing incompressible boson or fermion matter with constituents with masses of the order of the neutron mass one finds that the maximum mass is the Misner mass. For a small electric charge, our analytical approximating scheme, valid in first order in the star's electric charge, shows that the maximum mass increases relatively to the uncharged case, whereas the minimum possible radius decreases, an expected effect since the new field is repulsive, aiding the pressure to sustain the star against gravitational collapse. (orig.)

  10. Role of Individual Positive Charges in the Membrane Orientation and Activity of Transporters of the Small Multidrug Resistance Family

    NARCIS (Netherlands)

    Kolbusz, Magdalena A.; Slotboom, Dirk Jan; Lolkema, Juke S.


    The effect of individual positively charged residues on the orientation in the membrane was analyzed in three dual-topology transporters of the small. multidrug resistance (SMR) family: AAVE4701aave of Acidovorax avenae, EMREecol of Escherichia coli, and RRUA0272rrub of Rhodospirillum rubrum. It is

  11. Charge modification of the endothelial surface layer modulates the permeability barrier of isolated rat mesenteric small arteries

    NARCIS (Netherlands)

    van Haaren, Paul M. A.; VanBavel, Ed; Vink, Hans; Spaan, Jos A. E.


    We hypothesized that modulation of the effective charge density of the endothelial surface layer ( ESL) results in altered arterial barrier properties to transport of anionic solutes. Rat mesenteric small arteries ( diameter similar to 190 mu m) were isolated, cannulated, perfused, and superfused

  12. Proton migration along the membrane surface in the absence of charged or titratable groups

    International Nuclear Information System (INIS)

    Springer, A.


    Proton diffusion along membrane surfaces is thought to be essential for many cellular processes such as energy transduction. For example, proton diffusion along membrane surfaces is considered to be the dominant mechanism of proton exchange between membrane sites of high and low proton concentrations. For the investigation of this mechanism, kinetic experiments on proton diffusion are evaluated to determine the ability of lipid membranes to retain protons on their surfaces. Experiments on different lipid bilayer membranes (DPhPC, DPhPE and GMO) are performed under the influence of two types of mobile buffer molecules (Capso, NH4CL). During these experiments the surface diffusion of photolytically released protons is visualized in terms of fluorescence changes of a lipid bound pH-sensitive dye (DHPE +fluorescein). The protons under investigation are released by flash photolysis of a hydrophobic caged compound (DMCM, caged diethyl phosphate). The experimental data confirm the existence of an energy barrier, which prevents the protons from escaping into the bulk. So far this effect was attributed to the proton binding to titrateable groups (e.g. ethanolamine) or electrostatic forces created by charged moieties (e.g. phosphate groups) on the membrane/water interface. However, upon removal of the titrateable groups and charged moieties from the membrane surface, a significant energy barrier remained as indicated by the experiments with glycerol monooleate (GMO) bilayers. To estimate the size of the barrier a semi-analytical model is presented that describes the two and three dimensional proton diffusion and the related physical and chemical processes. Common models describe surface proton diffusion as a series of subsequent hopping processes between membrane-anchored buffer molecules. Our experiments provide evidence for an alternative model. We released membrane-bound caged protons by UV flashes and monitored their arrival at distant sites s by fluorescence

  13. Clients' Preferences for Small Groups vs. Individual Testing. (United States)

    Backman, Margaret E.; And Others

    Test takers' preferences for group versus individual administration of the Micro-TOWER System of Vocational Evaluation are reported. The system was administered to 211 clients at a vocational rehabilitation center, and consisted of work samples measuring the following job skills: record checking, filing, lamp assembly, message-taking, zip coding,…

  14. Small-Group Discourse: Establishing a Communication-Rich Classroom (United States)

    Quebec Fuentes, Sarah


    Establishing a communication-rich classroom can be difficult. This article describes the process and findings of a practitioner action research study addressing the question of how teachers can interact with their students while they are working in groups to encourage and enhance student-to-student communication. Recommended research-based teacher…

  15. X-Ray Beam Studies of Charge Sharing in Small Pixel, Spectroscopic, CdZnTe Detectors (United States)

    Allwork, Christopher; Kitou, Dimitris; Chaudhuri, Sandeep; Sellin, Paul J.; Seller, Paul; Veale, Matthew C.; Tartoni, Nicola; Veeramani, Perumal


    Recent advances in the growth of CdZnTe material have allowed the development of small pixel, spectroscopic, X-ray imaging detectors. These detectors have applications in a diverse range of fields such as medical, security and industrial sectors. As the size of the pixels decreases relative to the detector thickness, the probability that charge is shared between multiple pixels increases due to the non zero width of the charge clouds drifting through the detector. These charge sharing events will result in a degradation of the spectroscopic performance of detectors and must be considered when analyzing the detector response. In this paper charge sharing and charge loss in a 250 μm pitch CdZnTe pixel detector has been investigated using a mono-chromatic X-ray beam at the Diamond Light Source, U.K. Using a 20 μm beam diameter the detector response has been mapped for X-ray energies both above (40 keV) and below (26 keV) the material K-shell absorption energies to study charge sharing and the role of fluorescence X-rays in these events.

  16. Large and small sets with respect to homomorphisms and products of groups

    Directory of Open Access Journals (Sweden)

    Riccardo Gusso


    Full Text Available We study the behaviour of large, small and medium subsets with respect to homomorphisms and products of groups. Then we introduce the definition af a P-small set in abelian groups and we investigate the relations between this kind of smallness and the previous one, giving some examples that distinguish them.

  17. Connecting, interacting and supporting : Social capital, peer network and cognitive perspectives on small group teaching

    NARCIS (Netherlands)

    Brouwer, Jasperina


    No mass lectures anymore but small-group teaching; this is the current trend in higher education and the way universities hope to attract future students. Students get to know each other easily when they collaborate in small groups. The question arises whether dividing a cohort of students in small

  18. Key Informant Models for Measuring Group-Level Variables in Small Groups: Application to Plural Subject Theory (United States)

    Algesheimer, René; Bagozzi, Richard P.; Dholakia, Utpal M.


    We offer a new conceptualization and measurement models for constructs at the group-level of analysis in small group research. The conceptualization starts with classical notions of group behavior proposed by Tönnies, Simmel, and Weber and then draws upon plural subject theory by philosophers Gilbert and Tuomela to frame a new perspective…

  19. Small Business Administration (SBA) Loan Program Performance- Charge Off Rates as a Percent of Unpaid Principal Balance (UPB) Amount by Program (United States)

    Small Business Administration — Reflects charge off rates, as a percent of the UPB amounts, at the end of the fiscal year for the major loan programs and aggregate totals for the small direct and...

  20. An analysis of small changes in environment which resulted in diverse charge structures on 4 June 2012 in West Texas (United States)

    Chmielewski, V.; Bruning, E. C.; Ancell, B. C.


    As part of the Deep Convective Clouds and Chemistry field campaign, the disorganized cellular convection throughout West Texas on 4 June 2012 provided a unique opportunity to sample a full variety of charge structures in contemporaneous storms within tens of kilometers through the use of the West Texas Lightning Mapping Array. The surface moisture and related surface variables, while varying across the region, did not correlate to the observed charge structures, implying an above-surface influence dominated even what appeared to be a synoptically benign environment. Due to the close proximity of these storms to each other, a WRF ensemble was used to estimate the range of the mid-level environmental differences which may have resulted in the different charging within the storms. Most significantly, the representation of the elevated mixed layer, the base of which was near 700 mb (below cloud base), varied across the domain with the deepest and driest midlevel layers in the areas dominated by anomalous storms. This suggests that the above-surface dry modification of cloud parcels could be encouraging the positive charging of graupel within the cloud by limiting the warm cloud depth and increasing the availability of liquid in the mixed phase region. Besides the anomalous charge structures, these storms also contained fewer cloud-to-ground flashes and were slower to organize than those with a greater depth of moisture, although storms of both polarities were long-lasting. The case allows for a very unique examination of how small changes in environment can impact the storm-scale electrical and morphological properties. The ability of a set of idealized WRF models, using standard parameterizations, to capture any of these resulting differences in the overall charge structures given the very small changes in the environmental moisture across the region as resolved by the ensemble will be discussed. As part of the Deep Convective Clouds and Chemistry field campaign, the

  1. Framing Negotiation: Dynamics of Epistemological and Positional Framing in Small Groups during Scientific Modeling (United States)

    Shim, Soo-Yean; Kim, Heui-Baik


    In this study, we examined students' epistemological and positional framing during small group scientific modeling to explore their context-dependent perceptions about knowledge, themselves, and others. We focused on two small groups of Korean eighth-grade students who participated in six modeling activities about excretion. The two groups were…

  2. Risk transfer formula for individual and small group markets under the Affordable Care Act. (United States)

    Pope, Gregory C; Bachofer, Henry; Pearlman, Andrew; Kautter, John; Hunter, Elizabeth; Miller, Daniel; Keenan, Patricia


    The Affordable Care Act provides for a program of risk adjustment in the individual and small group health insurance markets in 2014 as Marketplaces are implemented and new market reforms take effect. The purpose of risk adjustment is to lessen or eliminate the influence of risk selection on the premiums that plans charge. The risk adjustment methodology includes the risk adjustment model and the risk transfer formula. This article is the third of three in this issue of the Medicare & Medicaid Research Review that describe the ACA risk adjustment methodology and focuses on the risk transfer formula. In our first companion article, we discussed the key issues and choices in developing the methodology. In our second companion paper, we described the risk adjustment model that is used to calculate risk scores. In this article we present the risk transfer formula. We first describe how the plan risk score is combined with factors for the plan allowable premium rating, actuarial value, induced demand, geographic cost, and the statewide average premium in a formula that calculates transfers among plans. We then show how each plan factor is determined, as well as how the factors relate to each other in the risk transfer formula. The goal of risk transfers is to offset the effects of risk selection on plan costs while preserving premium differences due to factors such as actuarial value differences. Illustrative numerical simulations show the risk transfer formula operating as anticipated in hypothetical scenarios.

  3. Simple supercapacitor charging scheme of an electric vehicle on small-scale hardware simulator: a prototype development for education purpose

    Directory of Open Access Journals (Sweden)

    Adnan Rafi Al Tahtawi


    Full Text Available Supercapacitor is one of electrical energy sources that have faster charging-discharging times when compared to other power sources, such as battery and fuel cell. Therefore, it is often used as an additional power source in an electric vehicle. In this paper, a prototype of small-scale electric vehicle simulator (EVS is built and a simple charging scheme of supercapacitor is used for education purpose. EVS is an electric vehicle prototype which can show the vehicle’s powertrain on small-scale configuration. Main components of this device are two direct current motors (DCMs with a linked axis of rotation. Therefore one of them will be able to act as a generator. The supercapacitor charging scheme is employed by controlling the relays. The hardware experimental result shows that the averages of charging current are proportional to the maximum slope angle of the road profiles. This scheme is simple due to the EVS utility and it is useful for education purpose.

  4. Counterion Association and Structural Conformation Change of Charged PAMAM Dendrimer in Aqueous Solutions Revealed by Small Angle Neutron Scattering

    International Nuclear Information System (INIS)

    Chen, Wei-Ren


    Our previous study of the structure change of poly(amidoamine) starburst dendrimers (PAMAM) dendrimer of generation 5 (G5) have demonstrated that although the overall molecular size is practically unaffected by increasing DCl concentration, a configurational transformation, from a diffusive density profile to a more uniform density distribution, is clearly observed. In the current paper, the focus is placed on understanding the effect of counterion identity on the inter-molecular structure and the conformational properties by studying the effect due to DBr using small angle neutron scattering (SANS) and integral equation theory. While the overall molecular size is found to be essentially unaffected by the change in the pD of solutions, it is surprising that the intra-molecular configurational transformation is not observed when DBr is used. The overall effective charge of a dendrimer is nearly the same for 1, the effect of counterion identity becomes significant, the effective charge carried by a charged G5 PAPAM protonated by DBr becomes smaller than that of solutions with DCl. As a consequence, a counterion identity dependence of counterion association is revealed: Under the same level of molecular protonation, the specific counterion association, which is defined as the ratio of bound chloride anions to positively charged amines per molecule, is larger for the G5 PAMAM dendrimer charged by DBr than the one by DCl.

  5. Mixed Domains Enhance Charge Generation and Extraction in Bulk-Heterojunction Solar Cells with Small-Molecule Donors

    KAUST Repository

    Alqahtani, Obaid


    The interplay between nanomorphology and efficiency of polymer-fullerene bulk-heterojunction (BHJ) solar cells has been the subject of intense research, but the generality of these concepts for small-molecule (SM) BHJs remains unclear. Here, the relation between performance; charge generation, recombination, and extraction dynamics; and nanomorphology achievable with two SM donors benzo[1,2-b:4,5-b]dithiophene-pyrido[3,4-b]-pyrazine BDT(PPTh), namely SM1 and SM2, differing by their side-chains, are examined as a function of solution additive composition. The results show that the additive 1,8-diiodooctane acts as a plasticizer in the blends, increases domain size, and promotes ordering/crystallinity. Surprisingly, the system with high domain purity (SM1) exhibits both poor exciton harvesting and severe charge trapping, alleviated only slightly with increased crystallinity. In contrast, the system consisting of mixed domains and lower crystallinity (SM2) shows both excellent exciton harvesting and low charge recombination losses. Importantly, the onset of large, pure crystallites in the latter (SM2) system reduces efficiency, pointing to possible differences in the ideal morphologies for SM-based BHJ solar cells compared with polymer-fullerene devices. In polymer-based systems, tie chains between pure polymer crystals establish a continuous charge transport network, whereas SM-based active layers may in some cases require mixed domains that enable both aggregation and charge percolation to the electrodes.

  6. Does small equal predatory? Analysis of publication charges and transparency of editorial policies in Croatian open access journals. (United States)

    Stojanovski, Jadranka; Marušić, Ana


    We approach the problem of "predatory" journals and publishers from the perspective of small scientific communities and small journals that may sometimes be perceived as "predatory". Among other characteristics of "predatory" journals two most relevant are their business model and the quality of the editorial work. We analysed 444 Croatian open access (OA) journals in the Hrčak (portal of Croatian scientific journals) digital journal repository for the presence of article processing charges as a business model and the transparency of editorial policies. The majority of journals do not charge authors or require submission or article processing charges, which clearly distinguishes them from "predatory" journals. Almost all Hrčak OA journals have publicly available information on editorial boards, including full names and affiliations, and detailed contact information for the editorial office at the Hrčak website. The journal names are unique and cannot be easily confused with another journal or intend to mislead about the journal's origin. While most journals provide information on peer review process, many do not provide guidelines for reviewers or other editorial and publication ethics standards. In order to clearly differentiate themselves from predatory journals, it is not enough for journals from small research communities to operate on non-commercial bases, but also to have transparent editorial policies.

  7. The effect of shape and roughness on the maximum induction charge for small particles

    International Nuclear Information System (INIS)

    Yu Deying; Adamiak, K; Castle, G S P


    Considerable analytical and numerical work has already been done on the charging characteristics of spherical and cylindrical particles. However, the majority of industrial processes involve irregular particles with rough surfaces. In this paper, the relationships between the magnitude of the induction charge and electric field on conductive particles in a uniform electric field as a function of the particle shape and roughness have been investigated. The COMSOL program based on the Finite Element Method was used in the numerical modelling. The results show that in evaluating the value of induction charge for a fixed applied electric field, as particle shape changes care must be taken to ensure that surface fields do not exceed breakdown. With this limitation it is shown that, for a given volume, a smooth sphere will gain more induction charge than either a fibrous or flake shaped particle. However for particles with rough surfaces for some levels of roughness it is possible to obtain a higher charge than an equivalent smooth sphere. These results suggest that the degree of surface roughness may be important in certain coating applications.

  8. Photogeneration of free charge carriers in .pi.-conjugated polymers with bulky side groups

    Czech Academy of Sciences Publication Activity Database

    Menšík, Miroslav; Jex, M.; Pfleger, Jiří; Jung, J.


    Roč. 404, 24 August (2012), s. 48-55 ISSN 0301-0104 R&D Projects: GA ČR(CZ) GAP205/10/2280; GA MŠk(CZ) OC10007 Institutional research plan: CEZ:AV0Z40500505 Institutional support: RVO:61389013 Keywords : photogeneration of free charge carriers * charge transfer states * localized excitation Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.957, year: 2012

  9. Peer-led small groups: Are we on the right track? (United States)

    Moore, Fraser


    Peer tutor-led small group sessions are a valuable learning strategy but students may lack confidence in the absence of a content expert. This study examined whether faculty reinforcement of peer tutor-led small group content was beneficial. Two peer tutor-led small group sessions were compared with one faculty-led small group session using questionnaires sent to student participants and interviews with the peer tutors. One peer tutor-led session was followed by a lecture with revision of the small group content; after the second, students submitted a group report which was corrected and returned to them with comments. Student participants and peer tutors identified increased discussion and opportunity for personal reflection as major benefits of the peer tutor-led small group sessions, but students did express uncertainty about gaps in their learning following these sessions. Both methods of subsequent faculty reinforcement were perceived as valuable by student participants and peer tutors. Knowing in advance that the group report would be corrected reduced discussion in some groups, potentially negating one of the major benefits of the peer tutor-led sessions. Faculty reinforcement of peer-tutor led small group content benefits students but close attention should be paid to the method of reinforcement.

  10. Professional Development of Mathematics Teachers toward the Facilitation of Small-Group Collaboration (United States)

    Tabach, Michal; Schwarz, Baruch B.


    Collaborative work in small groups is often a suitable context for yielding substantial individual learning outcomes. Indeed, small-group collaboration has recently become an educational goal rather than a means. Yet, this goal is difficult to attain, and students must be taught how to learn together. In this paper, we focus on how to prepare…

  11. 45 CFR 159.120 - Data submission for the individual and small group markets. (United States)


    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Data submission for the individual and small group... RELATING TO HEALTH CARE ACCESS HEALTH CARE REFORM INSURANCE WEB PORTAL § 159.120 Data submission for the individual and small group markets. (a) Health insurance issuers (hereinafter referred to as issuers) must...

  12. Effects of Small-Group Learning on Transfer: A Meta-Analysis (United States)

    Pai, Hui-Hua; Sears, David A.; Maeda, Yukiko


    This study investigated the potential benefit of small-group learning on transfer performance using the method of meta-analysis. Results showed positive support for the hypothesis that small-group learning can increase students' transfer performance (average effect size of 0.30). Unlike reviews of effects of cooperation on learning, this…

  13. Relevant Prior Knowledge Moderates the Effect of Elaboration during Small Group Discussion on Academic Achievement (United States)

    Van Blankenstein, Floris M.; Dolmans, Diana H. J. M.; Van der Vleuten, Cees P. M.; Schmidt, Henk G.


    This study set out to test whether relevant prior knowledge would moderate a positive effect on academic achievement of elaboration during small-group discussion. In a 2 × 2 experimental design, 66 undergraduate students observed a video showing a small-group problem-based discussion about thunder and lightning. In the video, a teacher asked…

  14. Relevant prior knowledge moderates the effect of elaboration during small group discussion on academic achievement

    NARCIS (Netherlands)

    F.M. van Blankenstein (Floris); D.H.J.M. Dolmans (Diana); C.P.M. van der Vleuten (Cees); H.G. Schmidt (Henk)


    textabstractThis study set out to test whether relevant prior knowledge would moderate a positive effect on academic achievement of elaboration during small-group discussion. In a 2 × 2 experimental design, 66 undergraduate students observed a video showing a small-group problem-based discussion

  15. Assessing the Internal Dynamics of Mathematical Problem Solving in Small Groups. (United States)

    Artzt, Alice F.; Armour-Thomas, Eleanor

    The purpose of this exploratory study was to examine the problem-solving behaviors and perceptions of (n=27) seventh-grade students as they worked on solving a mathematical problem within a small-group setting. An assessment system was developed that allowed for this analysis. To assess problem-solving behaviors within a small group a Group…

  16. The Mentoring Lab: A Small Group Approach for Managing Emotions from Multicultural Counselor Training (United States)

    Parker, Woodrow M.; Freytes, Magaly; Kaufman, Cindy J.; Woodruff, Rew; Hord, Rachel


    In an attempt to enable counselors-in-training to work through the strong emotional reactions experienced during the multicultural counseling course, a small group approach called the Multicultural Mentoring Lab has been developed. The purpose of the Multicultural Mentoring Lab is to provide a supportive, nonjudgmental, small group environment for…

  17. Learning and teaching in small groups: characteristics, benefits, problems and approaches. (United States)

    Jones, R W


    Small group learning may be defined as a group of learners demonstrating three common characteristics; active participation, a specific task and reflection. This article provides an overview of small group learning and teaching, describes the characteristics of this form of small group work, benefits, problems, potential causes of less than optimal sessions, and summarises specific approaches. These include tutorials, free-discussion groups, brainstorming, snowballing, buzz groups, paired (or one-to-one) discussion, clinical teaching, simulations, seminars, plenary sessions, problem-based learning, team-based learning, role plays, games and IT approaches. The article concludes with an emphasis on the importance of the teacher and a check list for use when planning, teaching and evaluating a small group session.

  18. "I Hate Group Work!": Addressing Students' Concerns about Small-Group Learning (United States)

    Allan, Elizabeth G.


    This article identifies the strategies used by architecture professors and their undergraduate students to mitigate common issues that students raise about group work. Based on participant-observation, interviews with students and faculty, and analysis of instructional materials and student work, this IRB-approved ethnographic case study…

  19. Structural influences on charge carrier dynamics for small-molecule organic photovoltaics (United States)

    Wang, Zhiping; Miyadera, Tetsuhiko; Saeki, Akinori; Zhou, Ying; Seki, Shu; Shibata, Yosei; Yamanari, Toshihiro; Matsubara, Koji; Yoshida, Yuji


    We investigated the structural influences on the charge carrier dynamics in zinc phthalocyanine/fullerene (ZnPc/C60) photovoltaic cells by introducing poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) and 2,5-bis(4-biphenylyl)-bithiophene (BP2T) between indium tin oxide and ZnPc layers. ZnPc films can be tuned to be round, long fiber-like, and short fiber-like structure, respectively. Time-resolved microwave conductivity measurements reveal that charge carrier lifetime in ZnPc/C60 bilayer films is considerably affected by the intra-grain properties. Transient photocurrent of ZnPc single films indicated that the charge carriers can transport for a longer distance in the long fiber-like grains than that in the round grains, due to the greatly lessened grain boundaries. By carefully controlling the structure of ZnPc films, the short-circuit current and fill factor of a ZnPc/C60 heterojunction solar cell with BP2T are significantly improved and the power conversion efficiency is increased to 2.6%, which is 120% larger than the conventional cell without BP2T.

  20. Structural influences on charge carrier dynamics for small-molecule organic photovoltaics

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Zhiping, E-mail:; Shibata, Yosei; Yamanari, Toshihiro; Matsubara, Koji; Yoshida, Yuji [Research Center for Photovoltaic Technologies, National Institute of Advanced Industrial Science and Technology (AIST), AIST Tsukuba Central 5, 1-1-1 Higashi, 305-8565 Tsukuba (Japan); Miyadera, Tetsuhiko, E-mail: [Research Center for Photovoltaic Technologies, National Institute of Advanced Industrial Science and Technology (AIST), AIST Tsukuba Central 5, 1-1-1 Higashi, 305-8565 Tsukuba (Japan); JST-PRESTO, Japan Science and Technology Agency (JST), 4-1-8 Honcho Kawaguchi, 332-0012 Saitama (Japan); Saeki, Akinori; Seki, Shu [Department of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, 565-0871 Suita, Osaka (Japan); Zhou, Ying [Electronics and Photonics Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), AIST Tsukuba Central 5, 1-1-1 Higashi, 305-8565 Tsukuba (Japan)


    We investigated the structural influences on the charge carrier dynamics in zinc phthalocyanine/fullerene (ZnPc/C{sub 60}) photovoltaic cells by introducing poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) and 2,5-bis(4-biphenylyl)-bithiophene (BP2T) between indium tin oxide and ZnPc layers. ZnPc films can be tuned to be round, long fiber-like, and short fiber-like structure, respectively. Time-resolved microwave conductivity measurements reveal that charge carrier lifetime in ZnPc/C{sub 60} bilayer films is considerably affected by the intra-grain properties. Transient photocurrent of ZnPc single films indicated that the charge carriers can transport for a longer distance in the long fiber-like grains than that in the round grains, due to the greatly lessened grain boundaries. By carefully controlling the structure of ZnPc films, the short-circuit current and fill factor of a ZnPc/C{sub 60} heterojunction solar cell with BP2T are significantly improved and the power conversion efficiency is increased to 2.6%, which is 120% larger than the conventional cell without BP2T.

  1. National trends of incidence, treatment, and hospital charges of isolated C-2 fractures in three different age groups. (United States)

    Kukreja, Sunil; Kalakoti, Piyush; Murray, Richard; Nixon, Menarvia; Missios, Symeon; Guthikonda, Bharat; Nanda, Anil


    Incidence of C-2 fracture is increasing in elderly patients. Patient age also influences decision making in the management of these fractures. There are very limited data on the national trends of incidence, treatment interventions, and resource utilization in patients in different age groups with isolated C-2 fractures. The aim of this study is to investigate the incidence, treatment, complications, length of stay, and hospital charges of isolated C-2 fracture in patients in 3 different age groups by using the Nationwide Inpatient Sample (NIS) database. The data were obtained from NIS from 2002 to 2011. Data on patients with closed fractures of C-2 without spinal cord injury were extracted using ICD-9-CM diagnosis code 805.02. Patients with isolated C-2 fractures were identified by excluding patients with other associated injuries. The cohort was divided into 3 age groups: 80 years. Incidence, treatment characteristics, inpatient/postoperative complications, and hospital charges (mean and total annual charges) were compared between the 3 age groups. A total of 10,336 patients with isolated C-2 fractures were identified. The majority of the patients were in the very elderly age group (> 80 years; 42.3%) followed by 29.7% in the 65- to 80-year age group and 28% in age group. From 2002 to 2011, the incidence of hospitalization significantly increased in the 65- to 80-year and > 80-year age groups (p age group (p = 0.287). Overall, 21% of the patients were treated surgically, and 12.2% of the patients underwent nonoperative interventions (halo and spinal traction). The rate of nonoperative interventions significantly decreased over time in all age groups (p age groups had a greater risk of inpatient/postoperative complications, nonroutine discharges, and longer hospitalization. The mean hospital charges were significantly higher in older age groups (p age groups. Simultaneously, there has been a steadily decreasing trend in the preference for nonoperative

  2. The Effects of Small Group Vocabulary Instruction on Second Grade Students' Expressive Vocabularies (United States)

    Fariss, Laura Lester


    The purpose of this study was to investigate the effectiveness of small group vocabulary instruction above and beyond whole group, read aloud vocabulary instruction, on second grade students' expressive vocabularies. This experimental study reflected a between-subjects design as three treatment groups were compared using a pretest, posttest within…

  3. Invented Spelling Activities in Small Groups and Early Spelling and Reading (United States)

    Martins, Margarida Alves; Salvador, Liliana; Albuquerque, Ana; Silva, Cristina


    Our aim was to assess the impact of an invented spelling programme conducted in small groups on children's written language acquisition in Portuguese. We expected the experimental group to have better post-test results than the control group in spelling and reading. Participants were 160 preschool-age children who were randomly divided into an…

  4. Autonomous charging to enable long-endurance missions for small aerial robots (United States)

    Mulgaonkar, Yash; Kumar, Vijay


    The past decade has seen an increased interest towards research involving Autonomous Micro Aerial Vehicles (MAVs). The predominant reason for this is their agility and ability to perform tasks too difficult or dangerous for their human counterparts and to navigate into places where ground robots cannot reach. Among MAVs, rotary wing aircraft such as quadrotors have the ability to operate in confined spaces, hover at a given point in space and perch1 or land on a flat surface. This makes the quadrotor a very attractive aerial platform giving rise to a myriad of research opportunities. The potential of these aerial platforms is severely limited by the constraints on the flight time due to limited battery capacity. This in turn arises from limits on the payload of these rotorcraft. By automating the battery recharging process, creating autonomous MAVs that can recharge their on-board batteries without any human intervention and by employing a team of such agents, the overall mission time can be greatly increased. This paper describes the development, testing, and implementation of a system of autonomous charging stations for a team of Micro Aerial Vehicles. This system was used to perform fully autonomous long-term multi-agent aerial surveillance experiments with persistent station keeping. The scalability of the algorithm used in the experiments described in this paper was also tested by simulating a persistence surveillance scenario for 10 MAVs and charging stations. Finally, this system was successfully implemented to perform a 9½ hour multi-agent persistent flight test. Preliminary implementation of this charging system in experiments involving construction of cubic structures with quadrotors showed a three-fold increase in effective mission time.

  5. Study of TATP: blast characteristics and TNT equivalency of small charges (United States)

    Pachman, J.; Matyáš, R.; Künzel, M.


    Blast wave parameters including incident overpressure, impulse and duration of the positive phase of the incident blast wave and its time of arrival were experimentally determined for 50 g charges of low bulk density () dry TATP (3,3,6,6,9,9-hexamethyl-1,2,4,5,7,8-hexoxonane). The results were compared with published TNT data, and TNT equivalencies were determined, resulting in the values of 70 % based on overpressure and 55 % based on impulse of the positive phase of the blast wave. Brisance by the Hess method (lead cylinder compression) was found to be about one-third of that for TNT (at density . Detonation velocities averaged around

  6. Application of a Motor Learning Treatment for Speech Sound Disorders in Small Groups. (United States)

    Skelton, Steven L; Richard, Jennifer T


    Speech sound treatment in the public schools is often conducted in small groups, but there are minimal data on the efficacy of group treatment. This study evaluated the efficacy of a motor learning-based treatment (Concurrent Treatment) provided to elementary-school students in small groups. Concurrent Treatment incorporates the randomized sequencing of various practice tasks (e.g., words, sentences, or storytelling) and can result in rapid speech sound acquisition during individual treatment settings. Twenty-eight 6- to 9-year-old children participated in a randomized pretest-posttest control group design. The experimental group received Concurrent Treatment, while the control group received treatment (if needed) after the study. Participants in the experimental group acquired their target speech sounds within 40 30-minute sessions in groups of up to four participants (effect size, d = 1.31). © The Author(s) 2016.

  7. Strategies of charge control in small photovoltaic systems; Estrategias de controle de carga em pequenos sistemas fotovoltaicos

    Energy Technology Data Exchange (ETDEWEB)

    Monteiro, Luis Guilherme; Zilles, Roberto [Universidade de Sao Paulo (USP), SP (Brazil). Inst. de Eletrotecnica e Energia. Lab. de Sistemas Fotovoltaicos], e-mail:, e-mail:


    Considering the necessity to optimize and to draw out the useful life of the rechargeable batteries in photovoltaic systems it is of custom to endow the systems with an equipment that plays this function. Its application, of adjusted form, can represent a significant reduction in the operational costs of these systems. In this paper the different strategies, and its particularities, used for the management of the state of charge are presented in small photovoltaic systems. In general, this management is made through the scan of voltage in the terminals of the accumulator with an electronic device called charge controller. The market offers a diversity of options for the designer of systems, that essentially vary in that refer to the strategy of commutation of the consumption and load circuits (for example, ON/OFF or PWM). The majority of the controllers for small systems does not allow to adjustment of the points of performance of the circuits of load and consumption. In many cases it is observed that the pre-adjusted points allow extreme discharges that make it harmless to one of functions that would have to play, or either, to protect the battery of extreme discharges. In this direction, this article makes an analysis of the different strategies of control and presents one criticizes to the products offered in the market for application in solar home systems. (author)

  8. Learning to Love Reading: A Self-Study on Fostering Students' Reading Motivation in Small Groups (United States)

    Miller, Rosa


    This study explores the relationship between small, differentiated reading groups and fourth-grade students' reading motivation. Using self-study methodology, the author examined her own process of implementing these reading groups through two cycles of action research. Data were analyzed from two different administrations of the Motivations for…

  9. Observational Learning of Academic and Social Behaviors during Small-Group Direct Instruction (United States)

    Ledford, Jennifer R.; Wolery, Mark


    Many studies have shown that small-group direct instruction is effective and efficient for teaching students with and without disabilities, although relatively few studies have been conducted with heterogeneous groups of preschool participants. In addition, previous studies have primarily assessed whether observational learning occurred for…

  10. Learning Science in Small Multi-Age Groups: The Role of Age Composition (United States)

    Kallery, Maria; Loupidou, Thomais


    The present study examines how the overall cognitive achievements in science of the younger children in a class where the students work in small multi-age groups are influenced by the number of older children in the groups. The context of the study was early-years education. The study has two parts: The first part involved classes attended by…

  11. Lexical Language-Related Episodes in Pair and Small Group Work (United States)

    Mayo, Maria Del Pilar Garcia; Zeitler, Nora


    The present study investigates whether learner set up in interaction, namely in pairs or small groups, influences the frequency and outcome of lexical language-related episodes (LREs) and L2 vocabulary learning. Thirty Spanish English as a foreign language (EFL) university learners took part in the study. They worked in four groups and seven pairs…

  12. Responsive Guided Reading in Grades K-5: Simplifying Small-Group Instruction (United States)

    Berne, Jennifer; Degener, Sophie C.


    Guided reading is a staple of elementary literacy instruction, yet planning and conducting reading groups can be time consuming and challenging. This hands-on book presents an innovative approach to guided reading that is manageable even for teachers who are new to small-group, differentiated reading instruction. Numerous classroom examples…

  13. Predicting Heats of Explosion of Nitroaromatic Compounds through NBO Charges and 15N NMR Chemical Shifts of Nitro Groups

    Directory of Open Access Journals (Sweden)

    Ricardo Infante-Castillo


    Full Text Available This work presents a new quantitative model to predict the heat of explosion of nitroaromatic compounds using the natural bond orbital (NBO charge and 15N NMR chemical shifts of the nitro groups (15NNitro as structural parameters. The values of the heat of explosion predicted for 21 nitroaromatic compounds using the model described here were compared with experimental data. The prediction ability of the model was assessed by the leave-one-out cross-validation method. The cross-validation results show that the model is significant and stable and that the predicted accuracy is within 0.146 MJ kg−1, with an overall root mean squared error of prediction (RMSEP below 0.183 MJ kg−1. Strong correlations were observed between the heat of explosion and the charges (R2 = 0.9533 and 15N NMR chemical shifts (R2 = 0.9531 of the studied compounds. In addition, the dependence of the heat of explosion on the presence of activating or deactivating groups of nitroaromatic explosives was analyzed. All calculations, including optimizations, NBO charges, and 15NNitro NMR chemical shifts analyses, were performed using density functional theory (DFT and a 6-311+G(2d,p basis set. Based on these results, this practical quantitative model can be used as a tool in the design and development of highly energetic materials (HEM based on nitroaromatic compounds.

  14. Charge transfer between the PO4- groups of DNA and the arginine + and lysine + side chains of proteins (United States)

    Bende, A.; Bogár, F.; Ladik, J.


    Using the HF + MP2 methods with full geometry optimizations the charge transfer (CT) from the PO4- groups of DNA to the arginine or lysine side chains of the proteins forming the nuclohistone cores were calculated. (X-ray investigation shows that in the nucleohistone core there are eight histones which are wrapped around by a DNA superhelix). We have found 0.21e and 0.26e CT, respectively. Knowing the structure of nucleohistones one can estimate a charge transfer at every fourth base pair. Taking as average 0.10e CT (there are also other attractive interactions) one can compute the concentrations of holes in DNA. From these one can obtain the dc conductivity for polyguanilic acid (the mobilities are known).

  15. Sigma model renormalization group flow, 'central charge' action, and Perelman's entropy

    International Nuclear Information System (INIS)

    Tseytlin, A. A.


    Zamolodchikov's c-theorem type argument (and also string theory effective action constructions) imply that the RG flow in 2d sigma model should be a gradient one to all loop orders. However, the monotonicity of the flow of the target-space metric is not obvious since the metric on the space of metric-dilaton couplings is indefinite. To leading (one-loop) order when the RG flow is simply the Ricci flow the monotonicity was proved by Perelman [G. Perelman, math.dg/0211159.] by constructing an 'entropy' functional which is essentially the metric-dilaton action extremized with respect to the dilaton with a condition that the target-space volume is fixed. We discuss how to generalize the Perelman's construction to all loop orders (i.e. all orders in α ' ). The resulting entropy is equal to minus the central charge at the fixed points, in agreement with the general claim of the c-theorem

  16. Charge localization and ordering in A2Mn8O16 hollandite group oxides: Impact of density functional theory approaches (United States)

    Kaltak, Merzuk; Fernández-Serra, Marivi; Hybertsen, Mark S.


    The phases of A2Mn8O16 hollandite group oxides emerge from the competition between ionic interactions, Jahn-Teller effects, charge ordering, and magnetic interactions. Their balanced treatment with feasible computational approaches can be challenging for commonly used approximations in density functional theory. Three examples (A = Ag, Li, and K) are studied with a sequence of different approximate exchange-correlation functionals. Starting from a generalized gradient approximation (GGA), an extension to include van der Waals interactions and a recently proposed meta-GGA are considered. Then local Coulomb interactions for the Mn 3 d electrons are more explicitly considered with the DFT + U approach. Finally, selected results from a hybrid functional approach provide a reference. Results for the binding energy of the A species in the parent oxide highlight the role of van der Waals interactions. Relatively accurate results for insertion energies can be achieved with a low-U and a high-U approach. In the low-U case, the materials are described as band metals with a high-symmetry, tetragonal crystal structure. In the high-U case, the electrons donated by A result in formation of local Mn3 + centers and corresponding Jahn-Teller distortions characterized by a local order parameter. The resulting degree of monoclinic distortion depends on charge ordering and magnetic interactions in the phase formed. The reference hybrid functional results show charge localization and ordering. Comparison to low-temperature experiments of related compounds suggests that charge localization is the physically correct result for the hollandite group oxides studied here. Finally, while competing effects in the local magnetic coupling are subtle, the fully anisotropic implementation of DFT + U gives the best overall agreement with results from the hybrid functional.

  17. Rate increase disclosure and review: definitions of "individual market" and "small group market." Final rule. (United States)


    This final rule amends a May 23, 2011, final rule entitled "Rate Increase Disclosure and Review". The final rule provided that, for purposes of rate review only, definitions of "individual market" and "small group market" under State rate filing laws would govern even if those definitions departed from the definitions that otherwise apply under title XXVII of the Public Health Service Act (PHS Act). The preamble to the final rule requested comments on whether this policy should apply in cases in which State rate filing law definitions of "individual market" and "small group market" exclude association insurance policies that would be included in these definitions for other purposes under the PHS Act. In response to comments, this final rule amends the definitions of "individual market" and "small group market" that apply for rate review purposes to include coverage sold to individuals and small groups through associations even if the State does not include such coverage in its definitions of individual and small group market. This final rule also updates standards for health insurance issuers regarding disclosure and review of unreasonable premium increases under section 2794 of the Public Health Service Act.

  18. 13 CFR 107.855 - Interest rate ceiling and limitations on fees charged to Small Businesses (“Cost of Money”). (United States)


    ... issued by the Small Business. (h) How to evaluate compliance with the Cost of Money ceiling. You must... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Interest rate ceiling and limitations on fees charged to Small Businesses (âCost of Moneyâ). 107.855 Section 107.855 Business Credit and...

  19. A qualitative assessment of faculty perspectives of small group teaching experience in Iraq. (United States)

    Saleh, Abubakir M; Shabila, Nazar P; Dabbagh, Ali A; Al-Tawil, Namir G; Al-Hadithi, Tariq S


    Although medical colleges in Iraq started recently to increasingly use small group teaching approach, there is limited research on the challenges, opportunities and needs of small group teaching in Iraq particularly in Kurdistan Region. Therefore, this study was aimed to assess the small group teaching experience in the 4(th) and 5(th) year of study in Hawler College of Medicine with a focus on characterizing the impressions of faculty members about how small group teaching is proceeding in the college. A qualitative study based on semi-structured interviews with 20 purposively selected faculty members was conducted. An interview guide was used for data collection that was around different issues related to small group teaching in medical education including planning, preparation, positive aspects, problems facing its implementation, factors related to it and recommendations for improvement. Qualitative data analysis comprised identifying themes that emerged from the review of transcribed interviews. Participants reported some positive experience and a number of positive outcomes related to this experience including better controlling the class, enhancing students' understanding of the subject, increasing interaction in the class, increasing the students' confidence, enhancing more contact between teachers and students, improving the presentation skills of the students and improving the teacher performance. The participants emphasized poor preparation and planning for application of this system and highlighted a number of problems and challenges facing this experience particularly in terms of poor infrastructure and teaching facilities, poor orientation of students and teachers, inadequate course time for some subjects and shortage of faculty members in a number of departments. The main suggestions to improve this experience included improving the infrastructure and teaching facilities, using more interactive teaching methods and better organization and management

  20. Small group learning: effect on item analysis and accuracy of self-assessment of medical students. (United States)

    Biswas, Shubho Subrata; Jain, Vaishali; Agrawal, Vandana; Bindra, Maninder


    Small group sessions are regarded as a more active and student-centered approach to learning. Item analysis provides objective evidence of whether such sessions improve comprehension and make the topic easier for students, in addition to assessing the relative benefit of the sessions to good versus poor performers. Self-assessment makes students aware of their deficiencies. Small group sessions can also help students develop the ability to self-assess. This study was carried out to assess the effect of small group sessions on item analysis and students' self-assessment. A total of 21 female and 29 male first year medical students participated in a small group session on topics covered by didactic lectures two weeks earlier. It was preceded and followed by two multiple choice question (MCQ) tests, in which students were asked to self-assess their likely score. The MCQs used were item analyzed in a previous group and were chosen of matching difficulty and discriminatory indices for the pre- and post-tests. The small group session improved the marks of both genders equally, but female performance was better. The session made the items easier; increasing the difficulty index significantly but there was no significant alteration in the discriminatory index. There was overestimation in the self-assessment of both genders, but male overestimation was greater. The session improved the self-assessment of students in terms of expected marks and expectation of passing. Small group session improved the ability of students to self-assess their knowledge and increased the difficulty index of items reflecting students' better performance.

  1. Small-scale structures in neutrals and charged aerosol particles as observed during the ECOMA/MASS rocket campaign

    Directory of Open Access Journals (Sweden)

    B. Strelnikov


    Full Text Available We present results of in situ measurements of neutral temperature during the ECOMA/MASS rocket campaign. We present and compare results of turbulence measurements conducted simultaneously by both in situ and doppler radar techniques. We show that the derived values of the turbulence energy dissipation rates are similar on average. We also find a region with a near adiabatic lapse rate with turbulence detected at the upper and lower edge. We note that it is consistent with expectation for a Kelvin-Helmholtz instability. We also present an estimate of the Schmidt numbers, Sc, for the charged aerosols that utilizes in situ measured small-scale density fluctuations of charged aerosols and both in situ and radar turbulence measurements. The derived Schmidt numbers fall within the range between 100 and 4500. This result agrees with previous estimates based on multi-frequency observations of PMSE (Rapp et al., 2008 and also with estimates of microphysical parameters presented in the companion paper by Rapp et al. (2009.

  2. Small-scale structures in neutrals and charged aerosol particles as observed during the ECOMA/MASS rocket campaign

    Directory of Open Access Journals (Sweden)

    B. Strelnikov


    Full Text Available We present results of in situ measurements of neutral temperature during the ECOMA/MASS rocket campaign. We present and compare results of turbulence measurements conducted simultaneously by both in situ and doppler radar techniques. We show that the derived values of the turbulence energy dissipation rates are similar on average. We also find a region with a near adiabatic lapse rate with turbulence detected at the upper and lower edge. We note that it is consistent with expectation for a Kelvin-Helmholtz instability.

    We also present an estimate of the Schmidt numbers, Sc, for the charged aerosols that utilizes in situ measured small-scale density fluctuations of charged aerosols and both in situ and radar turbulence measurements. The derived Schmidt numbers fall within the range between 100 and 4500. This result agrees with previous estimates based on multi-frequency observations of PMSE (Rapp et al., 2008 and also with estimates of microphysical parameters presented in the companion paper by Rapp et al. (2009.

  3. A Project Team Analysis Using Tuckman's Model of Small-Group Development. (United States)

    Natvig, Deborah; Stark, Nancy L


    Concerns about equitable workloads for nursing faculty have been well documented, yet a standardized system for workload management does not exist. A project team was challenged to establish an academic workload management system when two dissimilar universities were consolidated. Tuckman's model of small-group development was used as the framework for the analysis of processes and effectiveness of a workload project team. Agendas, notes, and meeting minutes were used as the primary sources of information. Analysis revealed the challenges the team encountered. Utilization of a team charter was an effective tool in guiding the team to become a highly productive group. Lessons learned from the analysis are discussed. Guiding a diverse group into a highly productive team is complex. The use of Tuckman's model of small-group development provided a systematic mechanism to review and understand group processes and tasks. [J Nurs Educ. 2016;55(12):675-681.]. Copyright 2016, SLACK Incorporated.

  4. How do small groups make decisions? : A theoretical framework to inform the implementation and study of clinical competency committees. (United States)

    Chahine, Saad; Cristancho, Sayra; Padgett, Jessica; Lingard, Lorelei


    In the competency-based medical education (CBME) approach, clinical competency committees are responsible for making decisions about trainees' competence. However, we currently lack a theoretical model for group decision-making to inform this emerging assessment phenomenon. This paper proposes an organizing framework to study and guide the decision-making processes of clinical competency committees.This is an explanatory, non-exhaustive review, tailored to identify relevant theoretical and evidence-based papers related to small group decision-making. The search was conducted using Google Scholar, Web of Science, MEDLINE, ERIC, and PsycINFO for relevant literature. Using a thematic analysis, two researchers (SC & JP) met four times between April-June 2016 to consolidate the literature included in this review.Three theoretical orientations towards group decision-making emerged from the review: schema, constructivist, and social influence. Schema orientations focus on how groups use algorithms for decision-making. Constructivist orientations focus on how groups construct their shared understanding. Social influence orientations focus on how individual members influence the group's perspective on a decision. Moderators of decision-making relevant to all orientations include: guidelines, stressors, authority, and leadership.Clinical competency committees are the mechanisms by which groups of clinicians will be in charge of interpreting multiple assessment data points and coming to a shared decision about trainee competence. The way in which these committees make decisions can have huge implications for trainee progression and, ultimately, patient care. Therefore, there is a pressing need to build the science of how such group decision-making works in practice. This synthesis suggests a preliminary organizing framework that can be used in the implementation and study of clinical competency committees.

  5. Risk Factor-tailored Small Group Education for Patients with First-time Acute Coronary Syndrome. (United States)

    Hwang, Seon Young; Kim, Jin Shil


    The purpose of this study was to evaluate the effects of a risk factor-tailored small group education on anxiety and depressive symptoms, self-efficacy and self-care compliance in patients with first-time acute coronary syndrome (ACS) for 12-month follow-up. A quasi-experimental pretest and post-test design was used. Patients were recruited from a national university hospital from 2010 to 2011 in Korea. The group education consisted of a 60-minute long video developed using multimedia contents including voice-recorded texts, flash animation, and video clips, with nurses' dialogue. The intervention group (n = 34) participated in group education using the multimedia video in a small group of patients with similar risk factors, and received periodic telephone counseling and text messages. The control group (n = 40) received usual care and counseling upon request. Depressive symptoms decreased, and self-efficacy and self-care compliance in the areas of medication, exercise, and healthy diet practice significantly increased in patients in the intervention group, compared with those in the control group. Risk factor-tailored small group education and periodic text message were an effective strategy for decreasing depression, and increasing self-efficacy and long-term compliance with lifestyle changes in patients with first-time ACS. We suggested that risk factor-tailored small group education need to be given for first-time ACS patients for psychological support and behavioral change in clinical practice. It is also comparable to individual approach to encourage psychological and behavioral change. Copyright © 2015. Published by Elsevier B.V.

  6. How do Small Groups Promote Behaviour Change? An Integrative Conceptual Review of Explanatory Mechanisms. (United States)

    Borek, Aleksandra J; Abraham, Charles


    Small groups are used to promote health, well-being, and personal change by altering members' perceptions, beliefs, expectations, and behaviour patterns. An extensive cross-disciplinary literature has articulated and tested theories explaining how such groups develop, function, and facilitate change. Yet these theoretical understandings are rarely applied in the development, description, and evaluation of health-promotion, group-based, behaviour-change interventions. Medline database, library catalogues, search engines, specific journals and reference lists were searched for relevant texts. Texts were reviewed for explanatory concepts or theories describing change processes in groups, which were integrated into the developing conceptual structure. This was designed to be a parsimonious conceptual framework that could be applied to design and delivery. Five categories of interacting processes and concepts were identified and defined: (1) group development processes, (2) dynamic group processes, (3) social change processes, (4) personal change processes, and (5) group design and operating parameters. Each of these categories encompasses a variety of theorised mechanisms explaining individual change in small groups. The final conceptual model, together with the design issues and practical recommendations derived from it, provides a practical basis for linking research and theory explaining group functioning to optimal design of group-based, behaviour-change interventions. © 2018 The Authors. Applied Psychology: Health and Well-Being published by John Wiley & Sons Ltd on behalf of International Association of Applied Psychology.

  7. Research on the influence of parking charging strategy based on multi-level extension theory of group decision making (United States)

    Cheng, Fen; Hu, Wanxin


    Based on analysis of the impact of the experience of parking policy at home and abroad, design the impact analysis process of parking strategy. First, using group decision theory to create a parking strategy index system and calculate its weight. Index system includes government, parking operators and travelers. Then, use a multi-level extension theory to analyze the CBD parking strategy. Assess the parking strategy by calculating the correlation of each indicator. Finally, assess the strategy of parking charges through a case. Provide a scientific and reasonable basis for assessing parking strategy. The results showed that the model can effectively analyze multi-target, multi-property parking policy evaluation.

  8. Basic steps in establishing effective small group teaching sessions in medical schools (United States)

    Meo, Sultan Ayoub


    Small-group teaching and learning has achieved an admirable position in medical education and has become more popular as a means of encouraging the students in their studies and enhance the process of deep learning. The main characteristics of small group teaching are active involvement of the learners in entire learning cycle and well defined task orientation with achievable specific aims and objectives in a given time period. The essential components in the development of an ideal small group teaching and learning sessions are preliminary considerations at departmental and institutional level including educational strategies, group composition, physical environment, existing resources, diagnosis of the needs, formulation of the objectives and suitable teaching outline. Small group teaching increases the student interest, teamwork ability, retention of knowledge and skills, enhance transfer of concepts to innovative issues, and improve the self-directed learning. It develops self-motivation, investigating the issues, allows the student to test their thinking and higher-order activities. It also facilitates an adult style of learning, acceptance of personal responsibility for own progress. Moreover, it enhances student-faculty and peer-peer interaction, improves communication skills and provides opportunity to share the responsibility and clarify the points of bafflement. PMID:24353692

  9. Effect of Fixed Charge Groups and Counter Ions on the Transport Phenomena of Paraffin and Olefin across Anhydrous Negatively Charged Membranes. (United States)

    Matsumoto; Tanioka; Kawauchi


    Permeability coefficients, apparent diffusion coefficients, and apparent solubility coefficients of n-butane and 1-butene gases across anhydrous sulfonated and carboxylated polyperfluorocarbon-type cation exchange membranes which have different counterions of Na+, Ag+, Co2+, and Ni2+ were investigated at 25 degreesC. Prior to the n-butane and 1-butene gas permeability measurements, O2 gas permeabilities were measured. From the results, it was shown that those membranes appeared to dense membranes. In each membrane, the permeability of 1-butene was higher than that of n-butane. In comparison with the same counterion membranes, the sulfonated membrane had higher permeability than the carboxylated membrane for both gases. The Ag+-form sulfonated membrane exhibited the highest permeability coefficient for 1-butene and the ideal separation factor of 1-butene/n-butane was 10.3. This is caused by the high solubility of 1-butene gas. From the calculated result using the MO method, it was shown that the interaction between the olefin and metal ions was weakened by the influence of a charged group. Therefore, the affinity between the olefin and Co2+ or Ni2+ did not function in the membrane as expected because of the divalent ions. This is the reason why the solubility coefficients of Co2+- and Ni2+-form membranes were smaller than those of the Ag+-form membrane. Copyright 1998 Academic Press.

  10. Female peers in small work groups enhance women's motivation, verbal participation, and career aspirations in engineering


    Dasgupta, Nilanjana; Scircle, Melissa McManus; Hunsinger, Matthew


    Advances in science, technology, engineering, and mathematics are critical to the American economy and require a robust workforce. The scarcity of women in this workforce is a well-recognized problem, but data-driven solutions to this problem are less common. We provide experimental evidence showing that gender composition of small groups in engineering has a substantial impact on undergraduate women’s persistence. Women participate more actively in engineering groups when members are mostly ...

  11. Second teaching: An exploration of cognitive factors in small group physics learning (United States)

    Novemsky, Lisa Forman

    This inquiry was focused on an exploration of introductory physics teaching. Alan Van Heuvelen's Overview Case Study (OCS) physics was the pedagogical approach involving guided small group problem solving and stressing concepts first, before mathematics. Second teaching is a new pedagogical construct based on Vygotsky's ideas. Structured small group activity follows traditional instruction facilitating learning for non-traditional students. It is a model of structured small group activity designed to follow traditional instruction to facilitate the learning process for students who find a physics optic (way of seeing) and physics language foreign. In informal small group settins students describe, explain, elaborate, test, and defend ideas in their own familiar vernacular as they collaborate in solving problems. Collective wisdom of a collaborative group, somewhat beyond the level for each individual member, is created then recreated through self-correction. Students improved significantly in physics knowledge. In a classroom setting, small groups of non-traditional physics students engaged in second teaching were observed. Written explanations to conceptual physics questions were analyzed. Development of language usage in relationship to introductory physics concept learning was studied. Overall physics learning correlated positively with gains in language clarity thus confirming the hypothesis that language development can be linked with gains in physics knowledge. Males and females were found to be significantly different in this respect. Male gains in language clarity were closely coupled with physics learning whereas female gains in the two measures were not coupled. Physics discourse, particularly in relationship to force and motion, seems to resonate with natural developmentally acquired sex-typical male but not female discourse. Thus, for males but not for females, physics learning proceeds in a seamless fashion wherein knowledge gains are coupled with

  12. Group O low titre only emergency donor panels for small combat teams. (United States)

    Doughty, Heidi; Maguire, A; Fitchett, G; Parker, P


    Military elements increasingly operate in small teams in remote areas with no immediate blood product support. Planners and operators may endorse collection of fresh whole blood from pretested donors in emergency situations. The biggest risk of transfusion is the accidental use of ABO incompatible blood which can be fatal. The risk may be mitigated by using only group O LOw (OLO) titre donors with plasma containing low levels of the naturally occurring antibody to group A and B red cells. This paper reviews the ABO blood group distribution in potential blood donors from a high readiness UK medical regiment and explores the feasibility of using only group OLO donors in small teams. A retrospective review of routine volunteer blood donor samples was undertaken at 6 monthly intervals during a 2-year period. Personnel were tested in groups when available during training to create multiple donor panels to simulate small teams. 206 donation samples were collected from 157 potential donors. All donors were acceptable based on the lifestyle questionnaire, serology and microbiology screen. Of the 206 samples reviewed, 85 (41%) were group O (D pos and D neg). 14 group O (16.5%) were shown to have high titre of anti-A or B. Therefore, 71, that is, 34% overall were suitable as OLO donors. The donor panel size varied from 15 to 44. The absolute number of OLO donors in each panel ranged from 4 to 17 and the number of O neg donors was 0-3. A third of samples were suitable as OLO donors; however, there were insufficient 'universal' donors within smaller subgroups (group O and group A donors or the use of a buddy-buddy blood group matrix. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  13. Developing Employment Interview and Interviewing Skills in Small-group Project Work. (United States)

    Hindle, Paul


    Discusses the value of communications skills in geographical education. Describes the use of realistic interviews that were a part of small-group project work. Explains that students wrote job specifications, a curriculum vitae, a cover letter, and conducted interview panels. (CMK)

  14. Developing Reflective Dispositions through Collaborative Knowledge-Building during Small Group Bible Study (United States)

    Toh, Tze Keong; Koh, Joyce Hwee Ling; Chai, Ching Sing


    This article explores the use of a constructivist pedagogical approach to cultivate reflective dispositions during small group Bible study. Conducted in a local church Bible class setting (n = 12), the instructional design emulated the reflective thinking process, while adopting collaborative knowledge-building as its pedagogical framework.…

  15. Small-Group Standardized Patient Encounter Improves Athletic Training Students' Psychosocial Intervention and Referral Skills (United States)

    Walker, Stacy E.; Weidner, Thomas G.; Thrasher, Ashley B.


    Context: Athletic trainers provide psychological support, counseling, intervention, and referral to patients during clinical practice. However, students are rarely exposed to real-life opportunities to develop these skills. Objective: To determine if a small-group standardized patient (SP) encounter improved athletic training students'…

  16. Taking It to the Classroom: Number Board Games as a Small Group Learning Activity (United States)

    Ramani, Geetha B.; Siegler, Robert S.; Hitti, Aline


    We examined whether a theoretically based number board game could be translated into a practical classroom activity that improves Head Start children's numerical knowledge. Playing the number board game as a small group learning activity promoted low-income children's number line estimation, magnitude comparison, numeral identification, and…

  17. What Do We Want Small Group Activities For? Voices from EFL Teachers in Japan (United States)

    Kato, Yoshitaka


    This paper discusses the fundamental issue of why small group activities are utilized in the language learning classroom. Although these activities have gained popularity in the field of Teaching English as a Second Language (TESL), supported by a sound theoretical base, few studies have so far examined the reasons why language teachers are…

  18. Creating in the Collective: Dialogue, Collaboration, and the Search for Understanding in the Jazz Small Group (United States)

    Branker, Anthony Daniel John


    What would happen if college students involved in jazz small group performance were given the opportunity to be musically independent and self-directed while working in their own collaborative space? What sorts of things would they experience? What kind of learning space would they create for themselves? The purpose of this study was to…

  19. Promoting Pre-Service Elementary Students' Understanding of Chemical Equilibrium through Discussions in Small Groups (United States)

    Bilgin, Ibrahim


    The purpose of this study was to investigate the effectiveness of small group discussion on students' conceptual understanding of chemical equilibrium. Students' understanding of chemical equilibrium concepts was measured using the Misconception Identification Test. The test consisted of 30 items and administered as pre-posttests to a total of 81…

  20. The Study of Small Groups and Microevolution: A Project for Physical Anthropology. (United States)

    Rice, Patricia C.


    Describes a hands-on project in which anthropology students play the role of professional physical anthropologist in collecting and analyzing data on a small group of contemporary humans. Use of simulated data to represent ancestral populations results in an analysis of microevolution. (KH)

  1. Exploring Young Children's Response to Three Genres of Literature in Small-Peer Groups (United States)

    Griffin, Jennifer Adams


    This teacher research studied second graders' small-group, peer-led discussions about three genres of literature--realistic fiction, biography picture books, and science information books--across one school year (during three units in the fall, winter, and spring). It set out to explore how this peer talk, in general, mediated children's responses…

  2. Strong Teens: A School-Based Small Group Experience for African American Males (United States)

    White, Nathan J.; Rayle, Andrea Dixon


    This article describes the school-based, small group adaptation of the existing Strong Teens Curriculum (STC) for African American male adolescents in high schools. The STC was created to equip adolescents with skills that promote more effective social interaction and enhance personal emotional and psychological wellness. The authors present a…

  3. Teaching Macroeconomics to the Visually Impaired: New Tactile Methods, Verbal Precision, and Small Groups (United States)

    Naples, Michele I.


    Visually-impaired students require tailored pedagogies to ensure their instruction is as high quality as for sighted students. They follow board work during class by referring to typed class notes provided ahead of time via a Braille reader, and in-class small groups solving problems create an inclusive "esprit de corps" and promote…

  4. Worrying about What Others Think: A Social-Comparison Concern Intervention in Small Learning Groups (United States)

    Micari, Marina; Pazos, Pilar


    Small-group learning has become commonplace in education at all levels. While it has been shown to have many benefits, previous research has demonstrated that it may not always work to the advantage of every student. One potential problem is that less-prepared students may feel anxious about participating, for fear of looking "dumb" in…

  5. Learning through Discussions: Comparing the Benefits of Small-Group and Large-Class Settings (United States)

    Pollock, Philip H.; Hamann, Kerstin; Wilson, Bruce M.


    The literature on teaching and learning heralds the benefits of discussion for student learner outcomes, especially its ability to improve students' critical thinking skills. Yet, few studies compare the effects of different types of face-to-face discussions on learners. Using student surveys, we analyze the benefits of small-group and large-class…

  6. Small-Group Cooperative Learning. The Best of ERIC on Educational Management Number 76. (United States)

    ERIC Clearinghouse on Educational Management, Eugene, OR.

    Annotations from 12 entries in the ERIC database were selected as significant and useful sources of information about small-group cooperative learning. Five of the citations are literature reviews. Among these is a meta-analysis, drawn from 217 studies, about the effects of cooperative learning on student achievement and interpersonal attraction;…

  7. Enactment of Teacher Identity in Resolving Student Disagreements in Small Group Peer Interactions (United States)

    Sharma, Bal Krishna


    This study presents a sequential analysis of the enactment of teacher identity in closing disagreements among students in small group peer interactions in an advanced academic writing class. In doing so, it discusses: (a) the micro-details of how oppositional stances and opinions are constructed, challenged and/or defended; (b) the sequential…

  8. Small group activities within academic communities improve the connectedness of students and faculty. (United States)

    Brandl, Katharina; Schneid, Stephen D; Smith, Sunny; Winegarden, Babbi; Mandel, Jess; Kelly, Carolyn J


    The University of California, San Diego, School of Medicine implemented a curriculum change that included reduction of lectures, incorporation of problem-based learning and other small group activities. Six academic communities were introduced for teaching longitudinal curricular content and organizing extracurricular activities. Surveys were collected from 904 first- and second-year medical students over 6 years. Student satisfaction data with their sense of connectedness and community support were collected before and after the implementation of the new curriculum. In a follow-up survey, medical students rated factors that contributed to their sense of connectedness with faculty and students (n = 134). Students' perception of connectedness to faculty significantly increased following implementation of a curriculum change that included academic communities. Students ranked small group clinical skills activities within academic communities significantly higher than other activities concerning their sense of connectedness with faculty. Students' perception of connectedness among each other was high at baseline and did not significantly change. Small group activities scored higher than extracurricular activities regarding students' connectedness among themselves. The implementation of a new curriculum with more small group educational activities including academic communities enhanced connectedness between students and faculty and resulted in an increased sense of community.

  9. Exploring Small Group Analysis of Instructional Design Cases in Online Learning Environments (United States)

    Trespalacios, Jesus


    The case-based approach is a constructivist instructional strategy that helps students apply their emerging knowledge by studying design problems in authentic real-world situations. One important instructional strategy in case-based instruction is to analyze cases in small groups before discussing them with the whole class. This study investigates…

  10. Female peers in small work groups enhance women's motivation, verbal participation, and career aspirations in engineering. (United States)

    Dasgupta, Nilanjana; Scircle, Melissa McManus; Hunsinger, Matthew


    For years, public discourse in science education, technology, and policy-making has focused on the "leaky pipeline" problem: the observation that fewer women than men enter science, technology, engineering, and mathematics fields and more women than men leave. Less attention has focused on experimentally testing solutions to this problem. We report an experiment investigating one solution: we created "microenvironments" (small groups) in engineering with varying proportions of women to identify which environment increases motivation and participation, and whether outcomes depend on students' academic stage. Female engineering students were randomly assigned to one of three engineering groups of varying sex composition: 75% women, 50% women, or 25% women. For first-years, group composition had a large effect: women in female-majority and sex-parity groups felt less anxious than women in female-minority groups. However, among advanced students, sex composition had no effect on anxiety. Importantly, group composition significantly affected verbal participation, regardless of women's academic seniority: women participated more in female-majority groups than sex-parity or female-minority groups. Additionally, when assigned to female-minority groups, women who harbored implicit masculine stereotypes about engineering reported less confidence and engineering career aspirations. However, in sex-parity and female-majority groups, confidence and career aspirations remained high regardless of implicit stereotypes. These data suggest that creating small groups with high proportions of women in otherwise male-dominated fields is one way to keep women engaged and aspiring toward engineering careers. Although sex parity works sometimes, it is insufficient to boost women's verbal participation in group work, which often affects learning and mastery.

  11. Effect of electrostatic charge, flow, delay and multiple actuations on the in vitro delivery of salbutamol from different small volume spacers for infants. (United States)

    Wildhaber, J H; Devadason, S G; Eber, E; Hayden, M J; Everard, M L; Summers, Q A; LeSouëf, P N


    A study was undertaken to determine the influences of electrostatic charge, flow, delay, and multiple actuations on the in vitro delivery of salbutamol generated by a pressurised metered dose inhaler (pMDI) from small volume spacers used in infants. Ten actuations from a salbutamol pMDI were drawn at different flow rates after either single or multiple actuations, with or without delay, through either static or reduced static spacers. An ionic detergent was used to reduce the charge of plastic spacers (Babyhaler, Babyspacer, Aerochamber, Nebuhaler). Electrostatic charge was measured using an electrometer. A multistage liquid impinger was used to determine the particle size distribution of the output of the pMDI through the spacers. Electrostatic charge on the surface of plastic spacers had the greatest influence on delivery, causing a decrease in drug delivery. Reducing charge by coating the surface with ionic detergent resulted in an increase of 46.5-71.1% (p particle delivery from small volume plastic spacers. Lower flow, delay, and multiple actuations resulted in decreased delivery from static spacers. Lower flow resulted in a decrease of 15% in small (particle delivery. Delay and multiple actuations resulted in a decrease of 40.7% and 76.0%, respectively, in small (particle delivery. The influences of lower flow, delay, and multiple actuations were greatly reduced or even eliminated by reducing charge. However, multiple actuations still resulted in a significant decreased delivery (p coating of plastic spacers resulted in no or reduced charge and hence in improved delivery. Lower flow, delay, and multiple actuations played a major part only in static spacers.

  12. Directions for new developments on statistical design and analysis of small population group trials. (United States)

    Hilgers, Ralf-Dieter; Roes, Kit; Stallard, Nigel


    Most statistical design and analysis methods for clinical trials have been developed and evaluated where at least several hundreds of patients could be recruited. These methods may not be suitable to evaluate therapies if the sample size is unavoidably small, which is usually termed by small populations. The specific sample size cut off, where the standard methods fail, needs to be investigated. In this paper, the authors present their view on new developments for design and analysis of clinical trials in small population groups, where conventional statistical methods may be inappropriate, e.g., because of lack of power or poor adherence to asymptotic approximations due to sample size restrictions. Following the EMA/CHMP guideline on clinical trials in small populations, we consider directions for new developments in the area of statistical methodology for design and analysis of small population clinical trials. We relate the findings to the research activities of three projects, Asterix, IDeAl, and InSPiRe, which have received funding since 2013 within the FP7-HEALTH-2013-INNOVATION-1 framework of the EU. As not all aspects of the wide research area of small population clinical trials can be addressed, we focus on areas where we feel advances are needed and feasible. The general framework of the EMA/CHMP guideline on small population clinical trials stimulates a number of research areas. These serve as the basis for the three projects, Asterix, IDeAl, and InSPiRe, which use various approaches to develop new statistical methodology for design and analysis of small population clinical trials. Small population clinical trials refer to trials with a limited number of patients. Small populations may result form rare diseases or specific subtypes of more common diseases. New statistical methodology needs to be tailored to these specific situations. The main results from the three projects will constitute a useful toolbox for improved design and analysis of small

  13. Small group gender ratios impact biology class performance and peer evaluations. (United States)

    Sullivan, Lauren L; Ballen, Cissy J; Cotner, Sehoya


    Women are underrepresented in science, technology, engineering, and mathematics (STEM) disciplines. Evidence suggests the microclimate of the classroom is an important factor influencing female course grades and interest, which encourages retention of women in STEM fields. Here, we test whether the gender composition of small (8-9 person) learning groups impacts course performance, sense of social belonging, and intragroup peer evaluations of intellectual contributions. Across two undergraduate active learning courses in introductory biology, we manipulated the classroom microclimate by varying the gender ratios of learning groups, ranging from 0% female to 100% female. We found that as the percent of women in groups increased, so did overall course performance for all students, regardless of gender. Additionally, women assigned higher peer- evaluations in groups with more women than groups with less women. Our work demonstrates an added benefit of the retention of women in STEM: increased performance for all, and positive peer perceptions for women.

  14. Individual and small group interactions in learning to teach with a hypermedia case (United States)

    Chung, Mi-Lee Ahn

    The purpose of this study was to investigate the similarities and differences of individual and small group preservice teachers' interactions with a hypermedia case. Preservice teachers' interactions with a hypermedia case were defined in terms of their (1) goals and perception of accomplishments of the goals, (2) use of features of the hypermedia case, and (3) types of questions and conflicts raised. Two individuals and two small groups of three preservice teachers participated by interacting with the hypermedia case which was developed to illustrate conceptual change science teaching in an elementary classroom. Most of the previous studies in this area have addressed large group use of hypermedia cases, and this study attempted to address the gap in the literature related to different social contexts, individuals and small groups, from the constructivist perspective. The assumptions of symbolic interactionism guided data collection from think-alouds and interviews. These multiple sources of data were used to understand the participants' construction of knowledge; data were analyzed and interpreted by a process of analytic induction. The major assertion was that the preservice teachers perceived the hypermedia case to be like a tool to link theory and practice of teaching. Three sub-assertions, and several supporting categories, also emerged from the data. These findings indicated that group learning experiences with the hypermedia case were more valuable than those of individuals. In general, preservice teachers benefited from learning how to teach with the hypermedia case in both settings. However, the individuals were not as satisfied as those in small groups, and the members of small groups interacted more actively with the hypermedia case as well as with the peers. The results of this study suggest that effective use of hypermedia cases takes place in a community of learners where the learners share the context and can draw upon the resources afforded by the

  15. Small Groups, Big Change: Preliminary Findings from the Sparks for Change Institute (United States)

    Kirsch, R.; Batchelor, R. L.; Habtes, S. Y.; King, B.; Crockett, J.


    The geoscience professoriate continues to under represent women and minorities, yet the value of diversity, both for science as well as recruiting and retaining diverse students, is well known. While there are growing numbers of early career tenure-track minority faculty, low retention rates pose a challenge for sustained diversity in the professoriate. Part of this challenge is the lack of institutional support and recognition in tenure and promotion pathways for faculty who undertake broadening participation efforts. Sparks for Change is a NSF Geoscience Opportunities for Leadership in Diversity (GOLD)-funded project that aims to change departmental culture to better value and reward inclusion and broadening participation efforts. By encouraging, recognizing, and rewarding diversity, equity, and inclusion (DEI) efforts at the department level, we aim to support and retain underrepresented minority (URM) faculty, who often disproportionately undertake these efforts, and to build more inclusive environments for faculty, staff and students alike. Sparks for Change utilizes a small group theory of change, arguing that the effort of a small group of committed individuals inside the organization is the best way to overcome the institutional inertia of academic departments that makes them resistant to change. For this effort, we propose that the ideal composition of these small groups is a junior faculty URM who is interested in DEI in the geosciences, a senior member of that same department who can lend weight to efforts and is positioned to help enact department policy, and an external broadening participation expert who can share best practices and provide accountability for the group. Eleven of these small groups, representing a range of institutions, will be brought together at the Sparks for Change Institute in Boulder, CO, in September. There they will receive leadership training on adaptive, transformative, and solidarity practices, share DEI experiences and

  16. Improving learning and confidence through small group, structured otoscopy teaching: a prospective interventional study. (United States)

    You, Peng; Chahine, Saad; Husein, Murad


    Otologic diseases are common and associated with significant health care costs. While accurate diagnosis relies on physical exam, existing studies have highlighted a lack of comfort among trainees with regards to otoscopy. As such, dedicated otoscopy teaching time was incorporated into the undergraduate medical curriculum in the form of a small group teaching session. In this study, we aimed to examine the effect of a small-group, structured teaching session on medical students' confidence with and learning of otoscopic examination. Using a prospective study design, an otolaryngologist delivered an one-hour, small group workshop to medical learners. The workshop included introduction and demonstration of otoscopy and pneumatic otoscopy followed by practice with peer feedback. A survey exploring students' confidence with otoscopy and recall of anatomical landmarks was distributed before(T1), immediately after(T2), and 1 month following the session(T3). One hundred and twenty five learners participated from February 2016 to February 2017. Forty nine participants with complete data over T1-T3 demonstrated significant improvement over time in confidence (Wilk's lambda = .09, F(2,48) = 253.31 p learning (Wilk's lambda = 0.34, F(2,47) = 24.87 p confidence with otoscopy and identification of otologic landmarks. Dedicated otoscopy teaching sessions may be a beneficial addition to the undergraduate medical curriculum.

  17. Student satisfaction and perceptions of small group process in case-based interprofessional learning. (United States)

    Curran, Vernon R; Sharpe, Dennis; Forristall, Jennifer; Flynn, Kate


    The small group, case-based learning approach is believed to be a useful strategy for facilitating interprofessional learning and interaction factors are said to have a significant effect on student interest, learning and satisfaction with such approaches. The purpose of our study was twofold: assess students' satisfaction with a blended approach to interprofessional learning which combined computer-mediated and face-to-face, case-based learning; and examine the relationship between student satisfaction and perceptions of the collaborative learning process. We introduced six interprofessional learning modules to approximately 520 undergraduate health professional students from medicine (61), nursing (351), pharmacy (20), and social work (89). All students were invited to complete an evaluation survey which assessed student satisfaction with the interprofessional learning experience and students' perceptions of the small group learning process. Students' satisfaction with interprofessional education was related to professional background. Students from across professions reported greater satisfaction with face-to-face, case-based learning when compared with other learning methods. A more positive perception of face-to-face, case-based learning was related to greater satisfaction with interprofessional learning. The findings support the case-based method in facilitating interprofessional learning and highlight the importance of effective facilitation of small-group collaborative learning to enhance student satisfaction with interprofessional learning experiences.

  18. Production of leading charged particles and leading charged-particle jets at small transverse momenta in pp collisions at $\\sqrt{s}$ = 8 TeV

    CERN Document Server

    Khachatryan, Vardan; Tumasyan, Armen; Adam, Wolfgang; Bergauer, Thomas; Dragicevic, Marko; Erö, Janos; Friedl, Markus; Fruehwirth, Rudolf; Ghete, Vasile Mihai; Hartl, Christian; Hörmann, Natascha; Hrubec, Josef; Jeitler, Manfred; Kiesenhofer, Wolfgang; Knünz, Valentin; Krammer, Manfred; Krätschmer, Ilse; Liko, Dietrich; Mikulec, Ivan; Rabady, Dinyar; Rahbaran, Babak; Rohringer, Herbert; Schöfbeck, Robert; Strauss, Josef; Treberer-Treberspurg, Wolfgang; Waltenberger, Wolfgang; Wulz, Claudia-Elisabeth; Mossolov, Vladimir; Shumeiko, Nikolai; Suarez Gonzalez, Juan; Alderweireldt, Sara; Bansal, Sunil; Cornelis, Tom; De Wolf, Eddi A; Janssen, Xavier; Knutsson, Albert; Lauwers, Jasper; Luyckx, Sten; Ochesanu, Silvia; Rougny, Romain; Van De Klundert, Merijn; Van Haevermaet, Hans; Van Mechelen, Pierre; Van Remortel, Nick; Van Spilbeeck, Alex; Blekman, Freya; Blyweert, Stijn; D'Hondt, Jorgen; Daci, Nadir; Heracleous, Natalie; Keaveney, James; Lowette, Steven; Maes, Michael; Olbrechts, Annik; Python, Quentin; Strom, Derek; Tavernier, Stefaan; Van Doninck, Walter; Van Mulders, Petra; Van Onsem, Gerrit Patrick; Villella, Ilaria; Caillol, Cécile; Clerbaux, Barbara; De Lentdecker, Gilles; Dobur, Didar; Favart, Laurent; Gay, Arnaud; Grebenyuk, Anastasia; Léonard, Alexandre; Mohammadi, Abdollah; Perniè, Luca; Randle-conde, Aidan; Reis, Thomas; Seva, Tomislav; Thomas, Laurent; Vander Velde, Catherine; Vanlaer, Pascal; Wang, Jian; Zenoni, Florian; Adler, Volker; Beernaert, Kelly; Benucci, Leonardo; Cimmino, Anna; Costantini, Silvia; Crucy, Shannon; Fagot, Alexis; Garcia, Guillaume; Mccartin, Joseph; Ocampo Rios, Alberto Andres; Poyraz, Deniz; Ryckbosch, Dirk; Salva Diblen, Sinem; Sigamani, Michael; Strobbe, Nadja; Thyssen, Filip; Tytgat, Michael; Yazgan, Efe; Zaganidis, Nicolas; Basegmez, Suzan; Beluffi, Camille; Bruno, Giacomo; Castello, Roberto; Caudron, Adrien; Ceard, Ludivine; Da Silveira, Gustavo Gil; Delaere, Christophe; Du Pree, Tristan; Favart, Denis; Forthomme, Laurent; Giammanco, Andrea; Hollar, Jonathan; Jafari, Abideh; Jez, Pavel; Komm, Matthias; Lemaitre, Vincent; Nuttens, Claude; Pagano, Davide; Perrini, Lucia; Pin, Arnaud; Piotrzkowski, Krzysztof; Popov, Andrey; Quertenmont, Loic; Selvaggi, Michele; Vidal Marono, Miguel; Vizan Garcia, Jesus Manuel; Beliy, Nikita; Caebergs, Thierry; Daubie, Evelyne; Hammad, Gregory Habib; Aldá Júnior, Walter Luiz; Alves, Gilvan; Brito, Lucas; Correa Martins Junior, Marcos; Dos Reis Martins, Thiago; Molina, Jorge; Mora Herrera, Clemencia; Pol, Maria Elena; Rebello Teles, Patricia; Carvalho, Wagner; Chinellato, Jose; Custódio, Analu; Melo Da Costa, Eliza; De Jesus Damiao, Dilson; De Oliveira Martins, Carley; Fonseca De Souza, Sandro; Malbouisson, Helena; Matos Figueiredo, Diego; Mundim, Luiz; Nogima, Helio; Prado Da Silva, Wanda Lucia; Santaolalla, Javier; Santoro, Alberto; Sznajder, Andre; Tonelli Manganote, Edmilson José; Vilela Pereira, Antonio; Bernardes, Cesar Augusto; Dogra, Sunil; Tomei, Thiago; De Moraes Gregores, Eduardo; Mercadante, Pedro G; Novaes, Sergio F; Padula, Sandra; Aleksandrov, Aleksandar; Genchev, Vladimir; Hadjiiska, Roumyana; Iaydjiev, Plamen; Marinov, Andrey; Piperov, Stefan; Rodozov, Mircho; Stoykova, Stefka; Sultanov, Georgi; Vutova, Mariana; Dimitrov, Anton; Glushkov, Ivan; Litov, Leander; Pavlov, Borislav; Petkov, Peicho; Bian, Jian-Guo; Chen, Guo-Ming; Chen, He-Sheng; Chen, Mingshui; Cheng, Tongguang; Du, Ran; Jiang, Chun-Hua; Plestina, Roko; Romeo, Francesco; Tao, Junquan; Wang, Zheng; Asawatangtrakuldee, Chayanit; Ban, Yong; Liu, Shuai; Mao, Yajun; Qian, Si-Jin; Wang, Dayong; Xu, Zijun; Zhang, Fengwangdong; Zhang, Linlin; Zou, Wei; Avila, Carlos; Cabrera, Andrés; Chaparro Sierra, Luisa Fernanda; Florez, Carlos; Gomez, Juan Pablo; Gomez Moreno, Bernardo; Sanabria, Juan Carlos; Godinovic, Nikola; Lelas, Damir; Polic, Dunja; Puljak, Ivica; Antunovic, Zeljko; Kovac, Marko; Brigljevic, Vuko; Kadija, Kreso; Luetic, Jelena; Mekterovic, Darko; Sudic, Lucija; Attikis, Alexandros; Mavromanolakis, Georgios; Mousa, Jehad; Nicolaou, Charalambos; Ptochos, Fotios; Razis, Panos A; Rykaczewski, Hans; Bodlak, Martin; Finger, Miroslav; Finger Jr, Michael; Assran, Yasser; Elgammal, Sherif; Ellithi Kamel, Ali; Mahmoud, Mohammed; Kadastik, Mario; Murumaa, Marion; Raidal, Martti; Tiko, Andres; Eerola, Paula; Voutilainen, Mikko; Härkönen, Jaakko; Karimäki, Veikko; Kinnunen, Ritva; Kortelainen, Matti J; Lampén, Tapio; Lassila-Perini, Kati; Lehti, Sami; Lindén, Tomas; Luukka, Panja-Riina; Mäenpää, Teppo; Peltola, Timo; Tuominen, Eija; Tuominiemi, Jorma


    The per-event yield of the highest transverse momentum charged particle and charged-particle jet, integrated above a given $p_{\\mathrm{T}}^{\\mathrm{min}}$ threshold starting at $p_{\\mathrm{T}}^{\\mathrm{min}} = $ 0.8 and 1 GeV, respectively, is studied in PbPb collisions at $\\sqrt{s} =$ 8 TeV. The particles and the jets are measured for absolute pseudorapidities lower than 2.4 and 1.9, respectively. The data are sensitive to the momentum scale at which parton densities saturate in the proton, to multiple partonic interactions, and other key aspects of the transition between the soft and hard QCD regimes in hadronic collisions.

  19. What Factors Influence Well-being of Students on Performing Small Group Discussion? (United States)

    Wulanyani, N. M. S.; Vembriati, N.


    Generally, Faculty of Medicine of Udayana University applied Small Group Discussion (SGD) in its learning process. If group problem solving succeeds, each individual of the group will individually succeed. However, the success is also determined by each individual’s level of psychological well-being. When the students are in the high level of wellbeing, they will feel comfortable in small group discussion, and teamwork will be effective. Therefore, it is needed to conduct a research which investigates how psychological factors, such as traits, needs, cognitive, and social intelligence, influence students’ wellbeing in performing SGD. This research is also initiated by several cases of students who prefer individual learning and take SGD merely to fulfill attendance requirement. If the students have good wellbeing, they will take the SGD process optimally. The subject of this research was 100 students of Faculty of Medicine of Udayana University. This survey research used psychological test assessment, Psychological well-being scale, and Social Intelligence scale to gain data analyzed quantitatively. The results showed that all aspects of traits together with aspects ‘need for rules and supervision’ affect social intelligence. Furthermore, social intelligence factor with cognitive factors influence wellbeing of the students in the process of SGD.

  20. Evolution of project-based learning in small groups in environmental engineering courses

    Directory of Open Access Journals (Sweden)

    Jesús M. Requies


    Full Text Available This work presents the assessment of the development and evolution of an active methodology (Project-Based Learning –PBL- implemented on the course “Unit Operations in Environmental Engineering”, within the bachelor’s degree in Environmental Engineering, with the purpose of decreasing the dropout rate in this course. After the initial design and implementation of this methodology during the first academic year (12/13, different modifications were adopted in the following ones (13-14, 14-15 & 15-16 in order to optimize the student’s and professor’s work load as well as correct some malfunctions observed in the initial design of the PBL. This active methodology seeks to make students the main architects of their own learning processes. Accordingly, they have to identify their learning needs, which is a highly motivating approach both for their curricular development and for attaining the required learning outcomes in this field of knowledge. The results obtained show that working in small teams (cooperative work enhances each group member’s self–learning capabilities. Moreover, academic marks improve when compared to traditional learning methodologies. Nevertheless, the implementation of more active methodologies, such as project-based learning, in small groups has certain specific characteristics. In this case it has been implemented simultaneously in two different groups of 10 students each one. Such small groups are more heterogeneoussince the presence of two highly motivated students or not can vary or affect the whole group’s attitude and academic results.

  1. Recommendations on vaccination for Asian small animal practitioners: a report of the WSAVA Vaccination Guidelines Group. (United States)

    Day, M J; Karkare, U; Schultz, R D; Squires, R; Tsujimoto, H


    In 2012 and 2013, the World Small Animal Veterinary Association (WSAVA) Vaccination Guidelines Group (VGG) undertook fact-finding visits to several Asian countries, with a view to developing advice for small companion animal practitioners in Asia related to the administration of vaccines to dogs and cats. The VGG met with numerous first opinion practitioners, small animal association leaders, academic veterinarians, government regulators and industry representatives and gathered further information from a survey of almost 700 veterinarians in India, China, Japan and Thailand. Although there were substantial differences in the nature and magnitude of the challenges faced by veterinarians in each country, and also differences in the resources available to meet those challenges, overall, the VGG identified insufficient undergraduate and postgraduate training in small companion animal microbiology, immunology and vaccinology. In most of the countries, there has been little academic research into small animal infectious diseases. This, coupled with insufficient laboratory diagnostic support, has limited the growth of knowledge concerning the prevalence and circulating strains of key infectious agents in most of the countries visited. Asian practitioners continue to recognise clinical infections that are now considered uncommon or rare in western countries. In particular, canine rabies virus infection poses a continuing threat to animal and human health in this region. Both nationally manufactured and international dog and cat vaccines are variably available in the Asian countries, but the product ranges are small and dominated by multi-component vaccines with a licensed duration of immunity (DOI) of only 1 year, or no description of DOI. Asian practitioners are largely unaware of current global trends in small animal vaccinology or of the WSAVA vaccination guidelines. Consequently, most practitioners continue to deliver annual revaccination with both core and non

  2. Investigations of solution-processed charge generation unit with low concentration of small molecule doped in p-type/HAT-CN{sub 6} for tandem OLED

    Energy Technology Data Exchange (ETDEWEB)

    Talik, N.A., E-mail: [Low Dimensional Material Research Centre (LDMRC), Physics Dept., Faculty of Science, University of Malaya, 50603 Kuala Lumpur (Malaysia); Yeoh, K.H. [Low Dimensional Material Research Centre (LDMRC), Physics Dept., Faculty of Science, University of Malaya, 50603 Kuala Lumpur (Malaysia); Centre for Photonics and Advanced Materials Research (CPR), Lee Kong Chian Faculty of Engineering and Science, University Tunku Abdul Rahman, 43000 Kajang, Selangor (Malaysia); Ng, C.Y.B. [Low Dimensional Material Research Centre (LDMRC), Physics Dept., Faculty of Science, University of Malaya, 50603 Kuala Lumpur (Malaysia); Tan, C.Y. [Centre of Advanced Manufacturing & Material Processing (AMMP), Department of Mechanical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur (Malaysia); Yap, B.K., E-mail: [Centre of Microelectronic and Nano Engineering (CeMNE), College of Engineering, Universiti Tenaga Nasional, 43000 Kajang, Selangor (Malaysia)


    We investigated the charge generation and injection mechanism in solution processed charge generation unit (CGU) used in our high performance tandem organic light emitting diode (OLED) via capacitance–voltage (C–V) and current density–voltage (J–V) measurements. By doping 2 wt% of small molecule 1,1-bis-(4-bis(4-tolyl)-aminophenyl) cyclohexene (TAPC) into Poly (N-vinylcarbazole) (PVK) as p-type layer of the CGU, we obtained more than two folds improvement in the tandem device efficiency compared to single device. The performance improvement of the TAPC doped CGU could be attributed to low built-in potential, large vacuum level shift as well as high charge density for efficient charge generation. - Highlights: • Charge-generation and injection mechanism in CGU for tandem OLED is investigated. • Small molecule, TAPC doped in p-type/HAT-CN{sub 6} has been used for tandem OLED. • The improvement attributes to the lower V{sub bi} and larger ΔV{sub L} in doped layer. • Narrower W and high carrier density also contribute to efficiency improvement.

  3. Influence of charge density and ionic strength on the aggregation process of cellulose nanocrystals in aqueous suspension, as revealed by small-angle neutron scattering. (United States)

    Cherhal, Fanch; Cousin, Fabrice; Capron, Isabelle


    Aggregation of rodlike colloidal particles is investigated here through the aggregation process by either increasing ionic strength or decreasing surface charge density of cellulose nanocrystals (CNCs). The form factor of the nanoparticles is characterized up to the Guinier plateau using small-angle neutron scattering (SANS) extended to very small scattering vector Q. Ionic strength, above the threshold of screening charges, brings aggregative conditions that induced fractal organizations for both charged and uncharged CNCs. These two structures display respective fractal dimensions of 2.1 for charged CNCs at high ionic strength and 2.3 for desulfated CNCs over more than a decade of the scattering vector Q, irrespective of salinity, revealing a denser structuration for neutral particles. This is discussed in the framework of aggregation of rodlike particles with an aspect ratio higher than 8. Furthermore, dilution of the rod gel led to disentanglement of the network of fractal aggregates with a subsequent macroscopic sedimentation of the suspensions, with a characteristic time that depends upon the ionic strength and surface charge density. It revealed a threshold independent of salt content around 2.5 g/L and the metastable out-of-equilibrium character of CNC suspensions.

  4. Discovery of group I introns in the nuclear small subunit ribosomal RNA genes of Acanthamoeba. (United States)

    Gast, R J; Fuerst, P A; Byers, T J


    The discovery of group I introns in small subunit nuclear rDNA (nsrDNA) is becoming more common as the effort to generate phylogenies based upon nsrDNA sequences grows. In this paper we describe the discovery of the first two group I introns in the nsrDNA from the genus Acanthamoeba. The introns are in different locations in the genes, and have no significant primary sequence similarity to each other. They are identified as group I introns by the conserved P, Q, R and S sequences (1), and the ability to fit the sequences to a consensus secondary structure model for the group I introns (1, 2). Both introns are absent from the mature srRNA. A BLAST search (3) of nucleic acid sequences present in GenBank and EMBL revealed that the A. griffini intron was most similar to the nsrDNA group I intron of the green alga Dunaliella parva. A similar search found that the A. lenticulata intron was not similar to any of the other reported group I introns. Images PMID:8127708

  5. Comparison of micelle structure of glycolipids with different head groups by small angle neutron scattering

    International Nuclear Information System (INIS)

    He, Lizhong; Middelberg, Anton; Hartmann, Thorsten; Niemeyer, Bernd; Garamus, V.M.; Willumeit, Regine


    Full text: Glycolipids such as n-alkyl- beta-D-glucopyranoside and n-alkyl- beta-D-maltopyranoside can self-assemble into different structures depending on solution conditions. Their amphiphilic properties enable them to serve as biosurfactants in biology and biotechnology, especially for solubilizing membrane proteins. The physicochemical properties of glycolipids have attracted attentions from several research groups, aiming to better understand their application in biological and environmental processes. For example, small angle neutron and X-ray scattering have been used to study micelle structures formed by glycolipids. Our previous work has shown that n-octyl-beta- D-glucopyranoside and n-octyl- beta-D-maltopyranoside form micelles with different structure, suggesting an important role of the sugar head group in micelle formation. In the present work, we further compare micelle structures of n-octyl- beta-Dglucopyranoside and n-octyl- beta-D-galactopyranoside. These two glycolipids have the same hydrophobic tail and their head sugar groups differ only in the conformation with one hydroxyl group pointing to different direction. Our SANS data together with phase behaviours reported by other group have suggested that a slight alteration of head group conformation can significantly affect self-assembly of glycolipids. (authors)

  6. Effects of communication strategy training on EFL students’ performance in small-group discussions

    Directory of Open Access Journals (Sweden)

    Stuart Benson


    Full Text Available In recent years, a number of studies have been conducted with regard to communication strategy training and performance on communicative tasks (Lam, 2009; Nakatani, 2010; Naughton, 2006. This study aims to add to the literature by examining how two strategies, clarifying/confirming and extending a conversation, and two methods of teaching the strategies, affected the interactional sequences and overall group discussion performance of EFL students at a university in Japan. Pre and posttreatment small-group discussions were recorded for assessment, and a stimulated recall interview was administered to determine the participants’ perceptions of their learning and language use. Posttest results reveal that the experimental groups that were taught predetermined phrases aimed at clarifying/confirming and extending a conversation employed such phrases more frequently than the control group. However, this employment of phrases did not lead to higher gains in group discussion skills as the control group enjoyed the largest gains from pre to posttest. The researchers consider the findings in light of previous research, and conclude with recommendations for future research on the topic with special regard to research design.

  7. Benefits of Group Foraging Depend on Prey Type in a Small Marine Predator, the Little Penguin. (United States)

    Sutton, Grace J; Hoskins, Andrew J; Arnould, John P Y


    Group foraging provides predators with advantages in over-powering prey larger than themselves or in aggregating small prey for efficient exploitation. For group-living predatory species, cooperative hunting strategies provide inclusive fitness benefits. However, for colonial-breeding predators, the benefit pay-offs of group foraging are less clear due to the potential for intra-specific competition. We used animal-borne cameras to determine the prey types, hunting strategies, and success of little penguins (Eudyptula minor), a small, colonial breeding air-breathing marine predator that has recently been shown to display extensive at-sea foraging associations with conspecifics. Regardless of prey type, little penguins had a higher probability of associating with conspecifics when hunting prey that were aggregated than when prey were solitary. In addition, success was greater when individuals hunted schooling rather than solitary prey. Surprisingly, however, success on schooling prey was similar or greater when individuals hunted on their own than when with conspecifics. These findings suggest individuals may be trading-off the energetic gains of solitary hunting for an increased probability of detecting prey within a spatially and temporally variable prey field by associating with conspecifics.

  8. [The Positionality of Caring Action: Small Group Dialogue in a Course on Nursing Ethics]. (United States)

    Chiang, Hsien-Hsien


    The content of nursing-ethics education has typically focused on the external standards of caring behavior and neglected the relationship between the ethical attitudes and internal experiences of caregivers. To explore the embodied experience in order to define the positionality of caring action, which is necessary to enrich the content of nursing ethics through small-group-learning-based dialogue. The researcher, as a participant observer, teaches a course on nursing ethics. Reflective analysis was used to analyze the data from the process of small group learning, a reflective group of faculty members, and 30 reflective journals submitted by 10 students. The results identified three items that were related to the positionality of caring action: the attitudes of belief, including the choice to belief and deep understanding; articulating the value system, including exploring affectivity and positionality; and cultivating the self through self-dialogues and dialogues with others. The attitudes of belief promote trust in interpersonal relationships. Articulating the value system deepens the meaning of caring. Cultivating the self may facilitate the ethical self.

  9. Charging machine

    International Nuclear Information System (INIS)

    Medlin, J.B.


    A charging machine for loading fuel slugs into the process tubes of a nuclear reactor includes a tubular housing connected to the process tube, a charging trough connected to the other end of the tubular housing, a device for loading the charging trough with a group of fuel slugs, means for equalizing the coolant pressure in the charging trough with the pressure in the process tubes, means for pushing the group of fuel slugs into the process tube and a latch and a seal engaging the last object in the group of fuel slugs to prevent the fuel slugs from being ejected from the process tube when the pusher is removed and to prevent pressure liquid from entering the charging machine. 3 claims, 11 drawing figures

  10. PBL curriculum improves medical students' participation in small-group tutorials. (United States)

    Wun, Y T; Tse, Eileen Y Y; Lam, T P; Lam, Cindy L K


    Group learning is the core of problem-based learning (PBL) but has not been extensively studied, especially in Asian students. This study compared students of PBL and non-PBL curricula in students' talking time and participation in small-group tutorials in a medical school in Asia. The proportions of student talking of 46 tutorials in three teaching rotations of the PBL curriculum and those of 43 corresponding tutorials in the non-PBL curriculum were counted. Twelve videotapes of tutorials (six from each curriculum), stratified for tutor, case scenario and students' learning stage, were randomly selected and transcribed. They were rated with the group-interaction (5 items) and active-participation (four items) tutorial assessment scales developed by Valle et al. These outcomes were compared between the students of PBL and non-PBL curricula. Students from the PBL curriculum talked significantly more. In only two (4.7%) of 43 tutorials in the non-PBL curriculum did the students talk more than the tutors; but students talked more than the tutors in 17 (37.0%) of 46 tutorials in the PBL curriculum. PBL students scored significantly higher than non-PBL students in all items except one item (respect to peers) of the tutorial assessment scales, and in the mean scores of both the group interaction scale (items 1-5) and the active participation scale (items 6-9). The results suggested that PBL starting from the early years of a medical curriculum was associated with more active student participation, interaction and collaboration in small-group tutorials.

  11. Electronic Structure of the Azide Group in 3¢-Azido-3¢-deoxythymidine (AZT Compared to Small Azide Compounds

    Directory of Open Access Journals (Sweden)

    Feng Wang


    Full Text Available Theoretical calculations for some structural and electronic properties of the azide moiety in the nucleoside reverse transcriptase (RT inhibitor 3¢-azido-3¢-deoxythymidine (AZT are reported. These properties, which include geometrical properties in three dimensional space, Hirshfeld charges, electrostatic potential (MEP, vibrational frequencies, and core and valence ionization spectra, are employed to study how the azide group is affected by the presence of a larger fragment. For this purpose, two small but important organic azides, hydrazoic acid and methyl azide, are also considered. The general features of trans Cs configuration for RNNN fragments[1] is distorted in the large AZT bio-molecule. Hirshfeld charge analysis shows charges are reallocated more evenly on azide when the donor group R is not a single atom. Infrared and photoelectron spectra reveal different aspects of the compounds. In conclusion, the electronic structural properties of the compounds depend on the specific property, the local structure and chemical environment of a species.

  12. Teachers' and students' verbal behaviours during cooperative and small-group learning. (United States)

    Gillies, Robyn M


    Teachers play a critical role in promoting interactions between students and engaging them in the learning process. This study builds on a study by Hertz-Lazarowitz and Shachar (1990) who found that during cooperative learning teachers' verbal behaviours were more helpful to and encouraging of their students' efforts while during whole-class instruction, their verbal behaviours tended to be more authoritarian, rigid, and impersonal. This study seeks to determine if teachers who implement cooperative learning engage in more facilitative learning interactions with their students than teachers who implement group work only. The study also seeks to determine if students in the cooperative groups model their teachers' behaviours and engage in more positive helping interactions with each other than their peers in the group work groups. The study involved 26 teachers and 303 students in Grades 8 to 10 from 4 large high schools in Brisbane, Australia. All teachers agreed to establish cooperative, small-group activities in their classrooms for a unit of work (4 to 6 weeks) once a term for 3 school terms. The teachers were audiotaped twice during these lessons and samples of the students' language, as they worked in their groups, were also collected at the same time. The results show that teachers who implement cooperative learning in their classrooms engage in more mediated-learning interactions and make fewer disciplinary comments than teachers who implement group work only. Furthermore, the students model many of these interactions in their groups. The study shows that when teachers implement cooperative learning, their verbal behaviour is affected by the organizational structure of the classroom.

  13. Comparison of small-group training with self-directed internet-based training in inhaler techniques. (United States)

    Toumas, Mariam; Basheti, Iman A; Bosnic-Anticevich, Sinthia Z


    To compare the effectiveness of small-group training in correct inhaler technique with self-directed Internet-based training. Pharmacy students were randomly allocated to 1 of 2 groups: small-group training (n = 123) or self-directed Internet-based training (n = 113). Prior to intervention delivery, all participants were given a placebo Turbuhaler and product information leaflet and received inhaler technique training based on their group. Technique was assessed following training and predictors of correct inhaler technique were examined. There was a significant improvement in the number of participants demonstrating correct technique in both groups (small group training, 12% to 63%; p training, 9% to 59%; p groups in the percent change (n = 234, p > 0.05). Increased student confidence following the intervention was a predictor for correct inhaler technique. Self-directed Internet-based training is as effective as small-group training in improving students' inhaler technique.

  14. Prospecting for customers in the small employer market: the experience of Arizona Health Care Group. (United States)

    Christianson, J B; Liu, C F; Schroeder, C M


    The findings of this study provide an interesting profile of the small employer "prospects" for prepaid health plans, where a prospect is defined as an employer that responds to a mass mailing effort with a request for information and further contact. About 60% of these prospects already have insurance, with 40% having group insurance. Therefore, a substantial portion of prospects are seeking to replace their existing health benefit package with a different one. Of those who do not offer existing insurance, the most common reason is that it is "too expensive" or the employer is "not profitable." A very small proportion do not offer insurance because they do not qualify for it due to medical underwriting considerations. Prospects tend to be larger than non-prospects in terms of sales, but employ lower wage employees, on average. About half of prospects are in service industries, a proportion typical of small employers in general. Somewhat surprisingly, most prospects have been in operation for over five years. They are not new firms attempting to establish their benefit packages. This is consistent with the findings on gross sales, suggesting that some maturity is necessary before an employer considers offering group health insurance as a benefit. The prepaid plans in this study also appeared to target established employers for their marketing efforts. In responding to questions about their attitudes towards health insurance, over one-quarter of prospects indicated that they would be unwilling to offer insurance at rates so low that they would not normally apply to the coverages offered by prepaid plans. Thus, although they were "prospects" by the study's definition, they were unlikely to eventually contract with prepaid plans. Those prospects that had offered insurance previously, but had discontinued it, tended to cite premium increases as the reason. This suggests that prospects among small employers are likely to be very price sensitive, and that further

  15. Technical Note: Harmonizing met-ocean model data via standard web services within small research groups (United States)

    Signell, Richard; Camossi, E.


    Work over the last decade has resulted in standardised web services and tools that can significantly improve the efficiency and effectiveness of working with meteorological and ocean model data. While many operational modelling centres have enabled query and access to data via common web services, most small research groups have not. The penetration of this approach into the research community, where IT resources are limited, can be dramatically improved by (1) making it simple for providers to enable web service access to existing output files; (2) using free technologies that are easy to deploy and configure; and (3) providing standardised, service-based tools that work in existing research environments. We present a simple, local brokering approach that lets modellers continue to use their existing files and tools, while serving virtual data sets that can be used with standardised tools. The goal of this paper is to convince modellers that a standardised framework is not only useful but can be implemented with modest effort using free software components. We use NetCDF Markup language for data aggregation and standardisation, the THREDDS Data Server for data delivery, pycsw for data search, NCTOOLBOX (MATLAB®) and Iris (Python) for data access, and Open Geospatial Consortium Web Map Service for data preview. We illustrate the effectiveness of this approach with two use cases involving small research modelling groups at NATO and USGS.

  16. Technical note: Harmonising metocean model data via standard web services within small research groups (United States)

    Signell, Richard P.; Camossi, Elena


    Work over the last decade has resulted in standardised web services and tools that can significantly improve the efficiency and effectiveness of working with meteorological and ocean model data. While many operational modelling centres have enabled query and access to data via common web services, most small research groups have not. The penetration of this approach into the research community, where IT resources are limited, can be dramatically improved by (1) making it simple for providers to enable web service access to existing output files; (2) using free technologies that are easy to deploy and configure; and (3) providing standardised, service-based tools that work in existing research environments. We present a simple, local brokering approach that lets modellers continue to use their existing files and tools, while serving virtual data sets that can be used with standardised tools. The goal of this paper is to convince modellers that a standardised framework is not only useful but can be implemented with modest effort using free software components. We use NetCDF Markup language for data aggregation and standardisation, the THREDDS Data Server for data delivery, pycsw for data search, NCTOOLBOX (MATLAB®) and Iris (Python) for data access, and Open Geospatial Consortium Web Map Service for data preview. We illustrate the effectiveness of this approach with two use cases involving small research modelling groups at NATO and USGS.

  17. A Small-Group Activity Introducing the Use and Interpretation of BLAST

    Directory of Open Access Journals (Sweden)

    Peter D. Newell


    Full Text Available As biological sequence data are generated at an ever increasing rate, the role of bioinformatics in biological research also grows. Students must be trained to complete and interpret bioinformatic searches to enable them to effectively utilize the trove of sequence data available. A key bioinformatic tool for sequence comparison and genome database searching is BLAST (Basic Local Alignment Search Tool. BLAST identifies sequences in a database that are similar to the entered query sequence, and ranks them based on the length and quality of the alignment. Our goal was to introduce sophomore and junior level undergraduate students to the basic functions and uses of BLAST with a small group activity lasting a single class period. The activity provides students an opportunity to perform a BLAST search, interpret the data output, and use the data to make inferences about bacterial cell envelope structure. The activity consists of two parts. Part 1 is a handout to be completed prior to class, complete with video tutorial, that reviews cell envelope structure, introduces key terms, and allows students to familiarize themselves with the mechanics of a BLAST search. Part 2 consists of a hands-on, web-based small group activity to be completed during the class period. Evaluation of the activity through student performance assessments suggests that students who complete the activity can better interpret the BLAST output parameters % query coverage and % max identity. While the topic of the activity is bacterial cell wall structure, it could be adapted to address other biological concepts.

  18. Small Marine Protected Areas in Fiji Provide Refuge for Reef Fish Assemblages, Feeding Groups, and Corals. (United States)

    Bonaldo, Roberta M; Pires, Mathias M; Guimarães, Paulo Roberto; Hoey, Andrew S; Hay, Mark E


    The establishment of no-take marine protected areas (MPAs) on coral reefs is a common management strategy for conserving the diversity, abundance, and biomass of reef organisms. Generally, well-managed and enforced MPAs can increase or maintain the diversity and function of the enclosed coral reef, with some of the benefits extending to adjacent non-protected reefs. A fundamental question in coral reef conservation is whether these benefits arise within small MPAs (reef organisms is largely decoupled from local adult reproduction. We examined the structure of fish assemblages, composition of fish feeding groups, benthic cover, and key ecosystem processes (grazing, macroalgal browsing, and coral replenishment) in three small (0.5-0.8 km2) no-take MPAs and adjacent areas where fisheries are allowed (non-MPAs) on coral reefs in Fiji. The MPAs exhibited greater species richness, density, and biomass of fishes than non-MPAs. Furthermore, MPAs contained a greater abundance and biomass of grazing herbivores and piscivores as well as a greater abundance of cleaners than fished areas. We also found differences in fish associations when foraging, with feeding groups being generally more diverse and having greater biomass within MPAs than adjacent non-MPAs. Grazing by parrotfishes was 3-6 times greater, and macroalgal browsing was 3-5 times greater in MPAs than in non-MPAs. On average, MPAs had 260-280% as much coral cover and only 5-25% as much macroalgal cover as their paired non-MPA sites. Finally, two of the three MPAs had three-fold more coral recruits than adjacent non-MPAs. The results of this study indicate that small MPAs benefit not only populations of reef fishes, but also enhance ecosystem processes that are critical to reef resilience within the MPAs.

  19. Small Marine Protected Areas in Fiji Provide Refuge for Reef Fish Assemblages, Feeding Groups, and Corals (United States)

    Pires, Mathias M.; Guimarães, Paulo Roberto; Hoey, Andrew S.; Hay, Mark E.


    The establishment of no-take marine protected areas (MPAs) on coral reefs is a common management strategy for conserving the diversity, abundance, and biomass of reef organisms. Generally, well-managed and enforced MPAs can increase or maintain the diversity and function of the enclosed coral reef, with some of the benefits extending to adjacent non-protected reefs. A fundamental question in coral reef conservation is whether these benefits arise within small MPAs (reef organisms is largely decoupled from local adult reproduction. We examined the structure of fish assemblages, composition of fish feeding groups, benthic cover, and key ecosystem processes (grazing, macroalgal browsing, and coral replenishment) in three small (0.5–0.8 km2) no-take MPAs and adjacent areas where fisheries are allowed (non-MPAs) on coral reefs in Fiji. The MPAs exhibited greater species richness, density, and biomass of fishes than non-MPAs. Furthermore, MPAs contained a greater abundance and biomass of grazing herbivores and piscivores as well as a greater abundance of cleaners than fished areas. We also found differences in fish associations when foraging, with feeding groups being generally more diverse and having greater biomass within MPAs than adjacent non-MPAs. Grazing by parrotfishes was 3–6 times greater, and macroalgal browsing was 3–5 times greater in MPAs than in non-MPAs. On average, MPAs had 260–280% as much coral cover and only 5–25% as much macroalgal cover as their paired non-MPA sites. Finally, two of the three MPAs had three-fold more coral recruits than adjacent non-MPAs. The results of this study indicate that small MPAs benefit not only populations of reef fishes, but also enhance ecosystem processes that are critical to reef resilience within the MPAs. PMID:28122006

  20. Small-Scale Systems of Galaxies. II. Properties of the NGC 4756 Group of Galaxies (United States)

    Grützbauch, R.; Kelm, B.; Focardi, P.; Trinchieri, G.; Rampazzo, R.; Zeilinger, W. W.


    This paper is part of a series that focuses on investigating galaxy formation and evolution in small-scale systems of galaxies in low-density environments. We present results from a study of the NGC 4756 group, which is dominated by the elliptical galaxy NGC 4756. The characteristics of the group are investigated through (1) the detailed investigation of the morphological, photometric, and spectroscopic properties of nine galaxies among the dominant members of the group; (2) the determination of the photometric parameters of the faint galaxy population in an area of 34'×34' centered on NGC 4756 and (3) an analysis of the X-ray emission in the area based on archival data. The nine member galaxies are located in the core part of the NGC 4756 group (a strip ~300 kpc in diameter, H0=70 km s-1 Mpc-1), which has a very loose configuration. The central part of the NGC 4756 group contains a significant fraction of early-type galaxies. Three new group members with previously unknown systemic velocities are identified, one of which is type dE. At about 7.5 arcmin southwest of NGC 4756 a substructure of the group is detected, including IC 829, MCG -2-33-35, MCG -2-33-36, and MCG -2-33-38, that meets the Hickson criteria for being a compact group. Most of the galaxies in this substructure show interaction signatures. We do not detect apparent fine structure and signatures of recent interaction events in the early-type galaxy population, with the exception of a strong dust lane in the elliptical galaxy MCG -2-33-38. However, this galaxy displays signatures of nuclear activity. Strong [O III], [N II], and [S II] line emission, combined with comparatively weak but broad Hα emission, suggests an intermediate Seyfert type classification. Although the area is heavily contaminated by the background cluster A1631, X-ray data suggest the presence of a hot intergalactic medium related to the detected X-ray emission of the group. The present results are discussed in the context of

  1. Small Group Learning in Medical Education: A Second Look at the Springer, Stanne, and Donovan Meta-Analysis. (United States)

    Colliver, Jerry A.; Feltovich, Paul J.; Verhulst, Steven J.


    Reviews the studies on which a meta-analysis by Springer, Stanne, and Donovan (1999) were based; the meta-analysis had concluded that small group learning in science, mathematics, engineering, and technology education is effective. Concludes that the meta-analysis' call for more widespread implementation of small group learning is not supported.…

  2. Clinical course teaching in transport of critically ill patients: Small group methods

    Directory of Open Access Journals (Sweden)

    Mohammad Taghi Beigmohammadi


    Full Text Available Critically ill patient transfer is potentially risky and may be lead to morbidity and mortality. Physicians' skill is very important for safe transport. We want to evaluate the effect of clinical course teaching on the promotion of physicians' abilities in the transport of critically ill patients. In an interventional study, 320 interns, male and female, were taught about patient transfer in two groups include in one day clinical course as the small group system (n=160 and other group the lecture base learning (n=160. In the clinical course, each participant under observation of an anesthesiologist in the operation room and ICU was acquainted with mask ventilation, intubation and learned to work with a defibrillator, infusion pump, portable ventilator and pulse oximeter. In lecture group, the anesthesiologist explained the topics by video and dummy. At the end of education course, the interns’ abilities were evaluated based on checklist method and scored by the project colleague in all educational items. Three hundred twenty interns, 122 males, and 198 females; were enrolled, two groups. The clinical course training caused improvements in the interns’ knowledge and abilities in intubation and use of the defibrillator and portable ventilator vs.lecture group significantly (P<0.005. The males were better than females in laryngoscopy, but the progress of the females was significantly better than males (P=0.003. The rate of adverse events was reduced significantly after clinical course teaching (P=0.041 Clinical course teaching could promote interns' clinical competencies in the transport of critically ill patients.

  3. Student perceptions of independent versus facilitated small group learning approaches to compressed medical anatomy education. (United States)

    Whelan, Alexander; Leddy, John J; Mindra, Sean; Matthew Hughes, J D; El-Bialy, Safaa; Ramnanan, Christopher J


    The purpose of this study was to compare student perceptions regarding two, small group learning approaches to compressed (46.5 prosection-based laboratory hours), integrated anatomy education at the University of Ottawa medical program. In the facilitated active learning (FAL) approach, tutors engage students and are expected to enable and balance both active learning and progression through laboratory objectives. In contrast, the emphasized independent learning (EIL) approach stresses elements from the "flipped classroom" educational model: prelaboratory preparation, independent laboratory learning, and limited tutor involvement. Quantitative (Likert-style questions) and qualitative data (independent thematic analysis of open-ended commentary) from a survey of students who had completed the preclerkship curriculum identified strengths from the EIL (promoting student collaboration and communication) and FAL (successful progression through objectives) approaches. However, EIL led to student frustration related to a lack of direction and impaired completion of objectives, whereas active learning opportunities in FAL were highly variable and dependent on tutor teaching style. A "hidden curriculum" was also identified, where students (particularly EIL and clerkship students) commonly compared their compressed anatomy education or their anatomy learning environment with other approaches. Finally, while both groups highly regarded the efficiency of prosection-based learning and expressed value for cadaveric-based learning, student commentary noted that the lack of grade value dedicated to anatomy assessment limited student accountability. This study revealed critical insights into small group learning in compressed anatomy education, including the need to balance student active learning opportunities with appropriate direction and feedback (including assessment). © 2015 American Association of Anatomists.

  4. Franchising as a Strategy for Combining Small and Large Group Advantages (Logics) in Social Entrepreneurship: A Hayekian Perspective


    Beckmann, Markus; Zeyen, Anica


    This article develops a Hayekian perspective on social franchising that distinguishes between the end-connected logic of the small group and the rule-connected logic of the big group. Our key claim is that mission-driven social entrepreneurs often draw on the small-group logic when starting their social ventures and then face difficulties when the process of scaling shifts their operations toward a big-group logic. In this situation, social franchising offers a strategy to replicate the small...

  5. Effect of electrostatic charge, flow, delay and multiple actuations on the in vitro delivery of salbutamol from different small volume spacers for infants.


    Wildhaber, J. H.; Devadason, S. G.; Eber, E.; Hayden, M. J.; Everard, M. L.; Summers, Q. A.; LeSouëf, P. N.


    BACKGROUND: A study was undertaken to determine the influences of electrostatic charge, flow, delay, and multiple actuations on the in vitro delivery of salbutamol generated by a pressurised metered dose inhaler (pMDI) from small volume spacers used in infants. METHODS: Ten actuations from a salbutamol pMDI were drawn at different flow rates after either single or multiple actuations, with or without delay, through either static or reduced static spacers. An ionic detergent was used to reduce...

  6. Problem-based learning: facilitating multiple small teams in a large group setting. (United States)

    Hyams, Jennifer H; Raidal, Sharanne L


    Problem-based learning (PBL) is often described as resource demanding due to the high staff-to-student ratio required in a traditional PBL tutorial class where there is commonly one facilitator to every 5-16 students. The veterinary science program at Charles Sturt University, Australia, has developed a method of group facilitation which readily allows one or two staff members to facilitate up to 30 students at any one time while maintaining the benefits of a small PBL team of six students. Multi-team facilitation affords obvious financial and logistic advantages, but there are also important pedagogical benefits derived from uniform facilitation across multiple groups, enhanced discussion and debate between groups, and the development of self-facilitation skills in students. There are few disadvantages to the roaming facilitator model, provided that several requirements are addressed. These requirements include a suitable venue, large whiteboards, a structured approach to support student engagement with each disclosure, a detailed facilitator guide, and an open, collaborative, and communicative environment.

  7. An interactive online approach to small-group student presentations and discussions. (United States)

    Thor, Der; Xiao, Nan; Zheng, Meixun; Ma, Ruidan; Yu, Xiao Xi


    Student presentations had been widely implemented across content areas, including health sciences education. However, due to various limitations, small-group student presentations in the classroom may not reach their full potential for student learning. To address challenges with presentations in the classroom, we redesigned the assignment by having students present and discuss online using VoiceThread, a cloud-based presentation and discussion tool. First-year students pursuing a Doctor of Dental Surgery degree were assigned into small groups to present physiology content and to discuss that content online. This assignment was similar to traditional student classroom presentations, with the exception that the entire assignment was conducted online. The primary purpose of this exploratory study was to investigate the impact of the online format on the discussion quality. Another purpose of the study was to examine students' perceptions of using VoiceThread for presenting and learning, as well as the online interactions between the presenter and audience. Students posted a higher number of questions and comments than required by the assignment. The questions from students were also higher level questions, and the answers to these questions were more thorough compared with what we had previously observed in classroom presentations. The survey results showed that students preferred using VoiceThread for presenting, learning from other presentations, and discussing presentation content over performing this process in the classroom. Preliminary findings suggested that having dental students make presentations and hold discussions online might help address the challenges of student presentations in the classroom. Copyright © 2017 the American Physiological Society.

  8. Effects of longitudinal small-group learning on delivery and receipt of communication skills feedback. (United States)

    Chou, Calvin L; Masters, Dylan E; Chang, Anna; Kruidering, Marieke; Hauer, Karen E


    Although feedback is a critical component of learning, recent data suggest that learners may discount feedback they receive. The emotional threat inherent in feedback can contribute to its ineffectiveness, particularly for sensitive topics like communication skills. Longitudinal relationships among peers may increase their sense of safety and soften the perceived threat of feedback to allow students to give, receive and potentially more effectively incorporate feedback. We studied the effects of prior shared learning experiences among medical students in the delivery and receipt of feedback on clinical (communication) skills. During a formative clinical skills examination, we divided Year 3 students at a US medical school into two subgroups comprising, respectively, small-group classmates from a 2-year longitudinal pre-clerkship clinical skills course (with prior peer-learning relationships), and peers with no prior shared small-group coursework. Students in both subgroups observed peers in a simulated clinical case and then provided feedback, which was videotaped, transcribed and coded. Feedback recipients also completed a survey on their perceptions of the feedback. Students valued the feedback they received and intended to enact it, regardless of whether they had prior peer-learning relationships. Coding of feedback revealed high specificity. Feedback providers who had prior peer-learning relationships with recipients provided more specific corrective feedback on communication skills than those with no such relationships (p = 0.014); there was no significant difference between subgroups in the provision of reinforcing feedback on communication skills. Year 3 medical student peers can deliver specific feedback on clinical skills; prior peer-learning relationships in pre-clerkship clinical skills courses enrich the provision of specific corrective feedback about communication skills. Feedback between peers with pre-existing peer-learning relationships represents

  9. A small-group functional balance intervention for individuals with Alzheimer disease: a pilot study. (United States)

    Ries, Julie D; Drake, Jamie Michelle; Marino, Christopher


    Individuals with Alzheimer disease (AD) have a higher risk of falls than their cognitively intact peers. This pilot study was designed to assess the feasibility and effectiveness of a small-group balance exercise program for individuals with AD in a day center environment. Seven participants met the inclusion criteria: diagnosis of AD or probable AD, medical stability, and ability to walk (with or without assistive device). We used an exploratory pre- and post-test study design. Participants engaged in a functional balance exercise program in two 45-minute sessions each week for eight weeks. Balance activities were functional and concrete, and the intervention was organized into constant, blocked, massed practice. Outcome measures included Berg Balance Scale (BBS), Timed Up and Go (TUG), and gait speed (GS; self-selected and fast assessed by an instrumented walkway). Data were analyzed by comparing individual change scores with previously identified minimal detectable change scores at the 90% confidence level (MDC90). Pre- and post-test data were acquired for five participants (two participants withdrew). The BBS improved in all five participants, and improved > or = 6.4 points (the MDC90 for the BBS in three participants. Four participants improved their performance on the TUG, and three participants improved > or = 4.09 seconds (the MDC90 for the TUG). Self-selected GS increased > or = 9.44 cm/sec (the MDC90 for gait speed) in three participants. Two participants demonstrated post-test self-selected GS comparable with their pretest fast GS. This pilot study suggests that a small-group functional balance intervention for individuals with AD is feasible and effective. Although participants had no explicit memory of the program, four of five improved in at least two outcome measures. Larger scale functional balance intervention studies with individuals with AD are warranted.

  10. Transformational leadership and group potency in small military units: The mediating role of group identification and cohesion

    Directory of Open Access Journals (Sweden)

    Carlos García-Guiu


    Full Text Available In the present study, we examined an exploratory model to assess the relationship between transformational leadership and group potency and analyze the mediating role of group identification and cohesion. The research was conducted with squads of the Spanish Army. The sample was composed of 243 members of 51 squads of operational units. Our findings highlighted the importance of the transformational leadership style of command of non-commissioned officers (NCOs due to its positive relationship with the group potency of the squad. We also analyzed the indirect relationships between transformational leadership and group identification and group cohesion and found that the latter variables played a mediating role between transformational leadership and group potency. The conclusions of this study are relevant due to the growing importance of transformational leadership and actions implemented at lower levels of the command chain for the success of missions of security organizations and defense.

  11. Found in translation: exporting patient-centered communication and small group teaching skills to China. (United States)

    Blatt, Benjamin; Kallenberg, Gene; Lang, Forrest; Mahoney, Patrick; Patterson, JoEllen; Dugan, Beverly; Sun, Shaobang


    The Chinese Medical Doctor's Association asked us to develop a train-the-trainers program in doctor-patient communication and in teaching skills for a select group of Chinese health care professionals, who would then serve as trainers for practicing physicians throughout China. The request came in the context of increasing doctor-patient friction related, in part, to the dissolution of the socialist health care safety net in China. In this article we recount the implementation of our 5-day training program in Beijing. We explore cross-cultural issues that arose in presenting the program's two principal training domains: small group teaching and patient-centered doctor-patient communication. We also explore the linguistic challenges we encountered as non-Chinese speaking teachers. Finally, we reflect on the lessons learned from this project that may be of value to others called upon to export Western doctor-patient communications training to other cultures. In this age of increasing globalization, cross-cultural sharing of medical education represents a growing trend.

  12. Educational network comparative analysis of small groups: Short- and long-term communications (United States)

    Berg, D. B.; Zvereva, O. M.; Nazarova, Yu. Yu.; Chepurov, E. G.; Kokovin, A. V.; Ranyuk, S. V.


    The present study is devoted to the discussion of small group communication network structures. These communications were observed in student groups, where actors were united with a regular educational activity. The comparative analysis was carried out for networks of short-term (1 hour) and long-term (4 weeks) communications, it was based on seven structural parameters, and consisted of two stages. At the first stage, differences between the network graphs were examined, and the random corresponding Bernoulli graphs were built. At the second stage, revealed differences were compared. Calculations were performed using UCINET software framework. It was found out that networks of long-term and short-term communications are quite different: the structure of a short-term communication network is close to a random one, whereas the most of long-term communication network parameters differ from the corresponding random ones by more than 30%. This difference can be explained by strong "noisiness" of a short-term communication network, and the lack of social in it.

  13. Inviting Argument by Analogy: Analogical-Mapping-Based Comparison Activities as a Scaffold for Small-Group Argumentation (United States)

    Emig, Brandon R.; McDonald, Scott; Zembal-Saul, Carla; Strauss, Susan G.


    This study invited small groups to make several arguments by analogy about simple machines. Groups were first provided training on analogical (structure) mapping and were then invited to use analogical mapping as a scaffold to make arguments. In making these arguments, groups were asked to consider three simple machines: two machines that they had…

  14. Electrically charged small soot particles in the exhaust of an aircraft gas-turbine engine combustor: comparison of model and experiment (United States)

    Sorokin, A.; Arnold, F.

    The emission of electrically charged soot particles by an aircraft gas-turbine combustor is investigated using a theoretical model. Particular emphasis is placed on the influence of the fuel sulfur content (FSC). The model considers the production of primary "combustion" electrons and ions in the flame zone and their following interaction with molecular oxygen, sulfur-bearing molecules (e.g. O 2, SO 2, SO 3, etc.) and soot particles. The soot particle size distribution is approximated by two different populations of mono-dispersed large and small soot particles with diameters of 20-30 and 5-7 nm, respectively. The effect of thermal ionization of soot and its interaction with electrons and positive and negative ions is included in the model. The computed positive and negative chemiion (CI) concentrations at the combustor exit and relative fractions of small neutral and charged soot particles were found to be in satisfactory agreement with experimental data. The results show that the FSC indeed may influence the concentration of negative CI at low fuel flow into combustor. Importantly the simulation indicates a very efficient mutual interaction of electrons and ions with soot particles with a large effect on both ion and charged soot particle concentrations. This result may be interpreted as a possible indirect effect of FSC on the growth and size distribution of soot particles.

  15. Oregon department of transportation small business group twice-monthly payments pilot project : summary report. (United States)


    Oregon Department of Transportation (ODOT) recently completed a pilot study on small business payment practices. In the study, three pilot projects were tested where payments to small business contractors were changed from a monthly payment to twice-...

  16. Impact of Spatial Distribution of Charged Groups in Core Poly(N-isopropylacrylamide)-Based Microgels on the Resultant Composite Structures Prepared by Seeded Emulsion Polymerization of Styrene. (United States)

    Watanabe, Takumi; Kobayashi, Chiaki; Song, Chihong; Murata, Kazuyoshi; Kureha, Takuma; Suzuki, Daisuke


    A series of raspberry-shaped composite microgels were synthesized by seeded emulsion polymerization of styrene in the presence of hydrogel particles with different distributions of charged groups. Unlike microgels whose charged groups are localized in their center,29 polystyrene nanoparticles were formed inside the core microgels when the microgels whose charged groups were localized on their surface were used as cores for seeded emulsion polymerization. The effects of the surface charge densities of the core microgels and the concentration of styrene monomer during the polymerization on the resultant structures of composite microgels were investigated. The surface structures of obtained composite microgels were mainly evaluated by electron microscopy, and their stimuli responsiveness was evaluated by dynamic light scattering and laser Doppler velocimetry. The internal structures of the composite microgels were visualized from ultrathin cross sections observed by transmission electron microscopy (TEM). Cryo-TEM was used to clarify the microscopic structures of composite microgels when they were in hydrated states. Through a series of characterizations, we summarize the effects of structures of core microgels on the resultant composite structures.

  17. Spontaneous mass generation and the small dimensions of the Standard Model gauge groups U(1, SU(2 and SU(3

    Directory of Open Access Journals (Sweden)

    Guillermo García Fernández


    The result follows from strong antiscreening of the running coupling for those larger groups (with an appropriately small number of flavors together with scaling properties of the Dyson–Schwinger equation for the fermion mass.

  18. A Review and Annotated Bibliography of the Literature Pertaining to Team and Small Group Performance (1989 to 1999)

    National Research Council Canada - National Science Library

    LaJoie, Andrew


    .... Training and military doctrine has been evolving to reflect this emphasis on teamwork. The purpose of this annotated bibliography is to review literature published over the last ten years concerning team and small group performance...

  19. Recent works carried out at the IDIEM by the group in charge of probabilistic strength of materials

    Directory of Open Access Journals (Sweden)

    Kittl, P.


    Full Text Available This updating review describes, from the conceptual standpoint, all the research works so far carried out at the IDIEM by the group in charge of Probabilistic Strength of Materials as well as research activities under way at present. This description considers three aspects. First, the general purposes of the commented discipline and the discussion of its theoretical foundations are presented. In the second place, an analysis is conducted in connection with materials subjected to diverse stresses of tension, compression, shearing, bending, torsion, eccentrical bending, and also subjected to buckling, eccentrical compressive and eccentrical tensile stresses: in all these cases the pertaining parameters of Weibull's function are determined. Thirdly, sundry engineering applications of said discipline are set out in such fields as, for example, soil mechanics, rock mechanics, seismology, nuclear reactors industry, fatigue, and concrete pavements. At last a brief description of research work now in progress is given.

    Se describen, desde un punto de vista conceptual, todos los trabajos desarrollados hasta la fecha por el grupo de Resistencia Probabilística de Materiales del IDIEM así como los que están actualmente en ejecución. Se consideran tres aspectos en la descripción. En primer lugar, se comentan los objetivos generales de la disciplina discutiendo su fundamentación teórica. En segundo lugar, se analizan casos de materiales sometidos a esfuerzos de tracción, compresión, corte, flexión, torsión, flexión excéntrica, pandeo, compresión y tracción excéntricas y la consecuente determinación de los parámetros de la función de Weibull en todos ellos. En tercer lugar, se mencionan las aplicaciones que esta disciplina tiene en la ingeniería, tales como en: mecánica de suelos, mecánica de rocas, fatiga, pavimentos de hormigón, sismología, industria nuclear, entre otras. Por último, se hace una sucinta descripción de los

  20. Amping it up on a small budget: Transforming inexpensive, commercial audio and video components into a useful charged particle spectrometer (United States)

    Pallone, Arthur

    Necessity often leads to inspiration. Such was the case when a traditional amplifier quit working during the collection of an alpha particle spectrum. I had a 15 battery-powered audio amplifier in my box of project electronics so I connected it between the preamplifier and the multichannel analyzer. The alpha particle spectrum that appeared on the computer screen matched expectations even without correcting for impedance mismatches. Encouraged by this outcome, I have begun to systematically replace each of the parts in a traditional charged particle spectrometer with audio and video components available through consumer electronics stores with the goal of producing an inexpensive charged particle spectrometer for use in education and research. Hopefully my successes, setbacks, and results to date described in this presentation will inform and inspire others.

  1. Flash propagation and inferred charge structure relative to radar-observed ice alignment signatures in a small Florida mesoscale convective system (United States)

    Biggerstaff, Michael I.; Zounes, Zackery; Addison Alford, A.; Carrie, Gordon D.; Pilkey, John T.; Uman, Martin A.; Jordan, Douglas M.


    A series of vertical cross sections taken through a small mesoscale convective system observed over Florida by the dual-polarimetric SMART radar were combined with VHF radiation source locations from a lightning mapping array (LMA) to examine the lightning channel propagation paths relative to the radar-observed ice alignment signatures associated with regions of negative specific differential phase (KDP). Additionally, charge layers inferred from analysis of LMA sources were related to the ice alignment signature. It was found that intracloud flashes initiated near the upper zero-KDP boundary surrounding the negative KDP region. The zero-KDP boundary also delineated the propagation path of the lightning channel with the negative leaders following the upper boundary and positive leaders following the lower boundary. Very few LMA sources were found in the negative KDP region. We conclude that rapid dual-polarimetric radar observations can diagnose strong electric fields and may help identify surrounding regions of charge.

  2. The networked minority: How a small group prevailed in a local windfarm conflict

    International Nuclear Information System (INIS)

    Anderson, Carmel


    This paper aims to explain through a qualitative case study how a small protest group prevailed during a local windfarm conflict in south-eastern Australia. A social capital analytical framework was developed to analyse the data. The analysis found that two communities inhabited the area for which the windfarm development was proposed. The public participation process failed to address the concerns of both communities and led to the emergence of a social network of resistance. The network had high stocks of bridging social capital, which enabled an effective protest that led to the abandonment of the development. Their effectiveness was inadvertently aided by the windfarm supporters who were unable to act collectively to defend their interests because socio-economic changes in the community among other factors had led to a depletion of their social capital. In this context, different democratic participatory processes were needed to address the concerns of the two communities. Guidance and tools for researching and developing the types of participatory processes needed for vulnerable communities with low social capital and those similar to the social network with high social capital are provided. These will inform community-appropriate public participation processes and participatory planning policy. - Highlights: ► A case study of a local social network's resistance to a windfarm is undertaken. ► The link between high social capital and resistance is confirmed. ► Successful protest groups can be aided by passive windfarm supporters. ► Protesters are likely to participate in well-designed participatory processes. ► Guidance for developing community-specific participatory processes is provided

  3. Assessment of impact of small group teaching among students in community medicine

    Directory of Open Access Journals (Sweden)

    Ranabir Pal


    Full Text Available Background: We conducted a study to assess the impact of small group teaching (SGT among students by feedback analysis to identify intricacy so that learning can be facilitated. Materials and Methods: This cross-sectional study was undertaken among 182 MBBS students studying at a teaching hospital at Gangtok. Students were provided with a questionnaire following an assignment on a scheduled topic. Students were asked to provide feedback on the modes of teaching-learning practiced in community medicine with the parameters of evaluation including assessment of presentation by faculty member in reference to relevance, sequencing, depth, interaction, etc., to the overall rating of presentations in different teaching-learning methods. Results: The faculty members were on the positive evaluation by the students in the SGT, which was preferred over "lectures" as the teaching-learning methods. Among SGTs "tutorials" were graded better than "practical," "seminar" and "field posting" on the basis of longer duration at a stretch. Among the parameters for evaluation, relevance, depth, and interaction in regard to scheduled topic of presentations, the rating was significantly higher in SGT than different other teaching-learning methods. Largely the students noted that the time devoted and number of hours/sessions allotted for each topic was adequate. Conclusion: All forms of SGT were on the positive appraisal by the students on their learning experience and were considered as a comprehensive tool for in-depth teacher-student interaction.

  4. Whistles of small groups of Sotalia fluviatilis during foraging behavior in southeastern Brazil (United States)

    Pivari, Daniela; Rosso, Sergio


    Whistle emissions were recorded from small groups of marine tucuxi dolphins (Sotalia fluviatilis) in two beaches located in an important biological reserve in the Cananéia estuary (25°03'S, 47°58'W), southeastern Brazil. A total of 17 h of acoustic data was collected when dolphins were engaged in a specific feeding foraging activity. The amount of 3235 whistles was recorded and 40% (n=1294) were analyzed. Seven acoustic whistle parameters were determined: duration (ms), number of inflection points, start and end frequency (kHz), minimum and maximum frequency (kHz), and frequency range (kHz). Whistles with up to four inflection points were found. Whistles with no inflection points and rising frequency corresponded to 85% (n=1104) of all analyzed whistles. Whistle duration varied from 38 to 627 ms (mean=229.6+/-109.9 ms), with the start frequency varying between 1 and 16 kHz (mean=8.16+/-3.0 kHz) and the end frequency between 2 and 18 kHz (mean=14.35+/-3.0 kHz). The importance of this study requires an accurate measurement of the whistles' emissions in an unusual foraging feeding behavior situation on two beaches where several tucuxis, mostly mother-calf pairs, are frequently present. These two beaches are located in a federal and state environment Environmental Protected Area threatened by the progressive increase of tourism.

  5. The 4-pyridylmethyl ester as a protecting group for glutamic and aspartic acids: 'flipping' peptide charge states for characterization by positive ion mode ESI-MS. (United States)

    Garapati, Sriramya; Burns, Colin S


    Use of the 4-pyridylmethyl ester group for side-chain protection of glutamic acid residues in solid-phase peptide synthesis enables switching of the charge state of a peptide from negative to positive, thus making detection by positive ion mode ESI-MS possible. The pyridylmethyl ester moiety is readily removed from peptides in high yield by hydrogenation. Combining the 4-pyridylmethyl ester protecting group with benzyl ester protection reduces the number of the former needed to produce a net positive charge and allows for purification by RP HPLC. This protecting group is useful in the synthesis of highly acidic peptide sequences, which are often beset by problems with purification by standard RP HPLC and characterization by ESI-MS. Copyright © 2014 European Peptide Society and John Wiley & Sons, Ltd.

  6. Evolution of small putative group I introns in the SSU rRNA gene locus of Phialophora species

    Directory of Open Access Journals (Sweden)

    Harris Lorena B


    Full Text Available Abstract Background Group I introns (specifically subgroup IC1 are common in the nuclear ribosomal RNA genes of fungi. While most range in length from more than 200 to nearly 1800 nucleotides (nt in length, several small putative (or degenerate group I introns have been described that are between 56 and 81 nt. Although small, previously we demonstrated that the PaSSU intron in the rRNA small subunit gene of Phialophora americana isolate Wang 1046 is capable of in vitro splicing using a standard group I intron pathway, thus qualifying it as a functional ribozyme. Findings Here, we describe eight short putative group I introns, ranging in length from 63 to 75 nt, in the rRNA small subunit genes of Phialophora isolates, a fungal genus that ranges from saprobic to pathogenic on plants and animals. All contain putative pairing regions P1, P7, and P10, as well as a pairing region formed between the middle of the intron and part of the 3' exon. The other pairing regions common in the core of standard group I introns are absent. However, parts of the 3' exon may aid in the stabilization of these small introns. Although the eight putative group I introns were from at least three species of Phialophora, phylogenetic analysis indicated that the eight are monophyletic. They are also monophyletic with the small introns of two lichen-forming fungi, Porpidia crustulata and Arthonia lapidicola. Conclusions The small putative group I introns in Phialophora have common features that may represent group I introns at their minima. They appear to have a single origin as indicated by their monophyly in phylogenetic analyses.

  7. Task Performance in Small Group Settings: The Role of Group Members' Self-Efficacy And Collective Efficacy and Group's Characteristics (United States)

    Khong, Jerrine Z. N.; Liem, Gregory Arief D.; Klassen, Robert M.


    The present study extends the literature by investigating the relative salience of self- and collective efficacy in predicting group performance among early adolescents in Indonesia. A total of 435 early adolescents (mean age 11.70 years, 53% female) were randomly assigned to groups of three to four and completed three group tasks (task 1:…

  8. Effects of Surface Charge and Functional Groups on the Adsorption and Binding Forms of Cu and Cd on Roots of indica and japonica Rice Cultivars

    Directory of Open Access Journals (Sweden)

    Zhao-Dong Liu


    Full Text Available This work was designed to understand the mechanisms of adsorption of copper (Cu and cadmium (Cd on roots of indica and japonica varieties of rice. Six varieties each of indica and japonica rice were grown in hydroponics and the chemical properties of the root surface were analyzed, including surface charges and functional groups (-COO- groups as measured by the streaming potential and attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR. Binding forms of heavy metals adsorbed on rice roots were identified using sequential extraction methods. In rice roots exposed to Cu and Cd solutions, Cu existed mainly in both exchangeable and complexed forms, whereas Cd existed mainly in the exchangeable form. The amounts of exchangeable Cu and Cd and total adsorbed metal cations on the roots of indica varieties were significantly greater than those on the roots of japonica varieties, and the higher negative charges and the larger number of functional groups on the roots of indica varieties were responsible for their higher adsorption capacity and greater binding strength for Cu and Cd. Surface charge and functional groups on roots play an important role in the adsorption of Cu and Cd on the rice roots.

  9. The effect of small peer group continuous quality improvement on the clinical practice of midwives in The Netherlands.

    NARCIS (Netherlands)

    Engels, Y.; Verheijen, Nicole; Fleuren, M; Mokkink, Henk; Grol, R.


    OBJECTIVE: To study the effects of small group continuous quality improvement (CQI) on the clinical practice of midwives in the Netherlands. DESIGN: Randomised pre-/post-test (balanced block). INTERVENTION: The CQI groups were assigned to either the set of peer review topics including 'perineal

  10. The effect of small peer group continuous quality improvement on the clinical practice of midwives in The Netherlands

    NARCIS (Netherlands)

    Engels, Y.; Verheijen, N.; Fleuren, M.; Mokkink, H.; Grol, R.


    Objective: To study the effects of small group continuous quality improvement (CQI) on the clinical practice of midwives in the Netherlands. Design: Randomised pre-/post-test (balanced block). Intervention: The CQI groups were assigned to either the set of peer review topics including 'perineal

  11. Pioneering small-group learning in Tanzanian emergency medicine: Investigating acceptability for physician learners

    Directory of Open Access Journals (Sweden)

    A G Lim


    Full Text Available Background. Emergency medicine (EM is a relatively new, but growing medical specialty in sub-Saharan Africa. African EM training programmes have used small-group learning (SGL modalities in their curricula. However, there is little knowledge of whether SGL modalities are perceived to be effective in these African EM training programmes. Objectives. To investigate the acceptability of SGL for physicians’ training in an academic Tanzanian emergency department using a novel EM curriculum. Methods. Using responses to a written questionnaire, we explored the perceived effectiveness of SGL compared with traditional didactic lectures among 38 emergency department physician learners in Dar es Salaam, Tanzania. Perceptions of SGL were identified from qualitative responses, and regression analyses were used to determine strength of association between quantitative outcomes. Results. Reported benefits of SGL included team building, simulation training, enhancement of procedural skills, and the opportunity to discuss opinions on clinical management. SGL scored more favourably with regard to improving clinical practice, enjoyment of learning, and building peer-to-peer relations. Lectures scored more favourably at improving medical knowledge. Preference towards SGL over lectures for overall training increased with years of clinical experience (95% confidence interval (CI 0.16 - 0.62, p=0.002, Spearman’s rho 0.51, and the perception that SGL reinforces learner-teacher relationships correlated with seniority within residency training (95% CI 0.14 - 0.86, p=0.007, Spearman’s rho 0.47. Conclusion. Techniques of SGL were perceived as effective at improving clinical practice in the emergency department setting. These modalities may be more favourably accepted by more experienced physician learners – therefore, new EM teaching programmes in Africa should consider these factors when targeting educational strategies for their respective regions and learner

  12. 77 FR 9882 - Arsenic Small Systems Compliance and Alternative Affordability Criteria Working Group; public... (United States)


    ... affordability criteria that give extra weight to small, rural, and lower income communities. This meeting will... held via the Internet using a Webcast and teleconference. Registrants will receive an Internet access... affordability criteria that give extra weight to small, rural, and lower income communities. Based upon input...

  13. CHARGE syndrome

    Directory of Open Access Journals (Sweden)

    Prasad Chitra


    Full Text Available Abstract CHARGE syndrome was initially defined as a non-random association of anomalies (Coloboma, Heart defect, Atresia choanae, Retarded growth and development, Genital hypoplasia, Ear anomalies/deafness. In 1998, an expert group defined the major (the classical 4C's: Choanal atresia, Coloboma, Characteristic ears and Cranial nerve anomalies and minor criteria of CHARGE syndrome. Individuals with all four major characteristics or three major and three minor characteristics are highly likely to have CHARGE syndrome. However, there have been individuals genetically identified with CHARGE syndrome without the classical choanal atresia and coloboma. The reported incidence of CHARGE syndrome ranges from 0.1–1.2/10,000 and depends on professional recognition. Coloboma mainly affects the retina. Major and minor congenital heart defects (the commonest cyanotic heart defect is tetralogy of Fallot occur in 75–80% of patients. Choanal atresia may be membranous or bony; bilateral or unilateral. Mental retardation is variable with intelligence quotients (IQ ranging from normal to profound retardation. Under-development of the external genitalia is a common finding in males but it is less apparent in females. Ear abnormalities include a classical finding of unusually shaped ears and hearing loss (conductive and/or nerve deafness that ranges from mild to severe deafness. Multiple cranial nerve dysfunctions are common. A behavioral phenotype for CHARGE syndrome is emerging. Mutations in the CHD7 gene (member of the chromodomain helicase DNA protein family are detected in over 75% of patients with CHARGE syndrome. Children with CHARGE syndrome require intensive medical management as well as numerous surgical interventions. They also need multidisciplinary follow up. Some of the hidden issues of CHARGE syndrome are often forgotten, one being the feeding adaptation of these children, which needs an early aggressive approach from a feeding team. As the child

  14. Effects of an additional small group discussion to cognitive achievement and retention in basic principles of bioethics teaching methods

    Directory of Open Access Journals (Sweden)

    Dedi Afandi


    Full Text Available Aim The place of ethics in undergraduate medical curricula is essential but the methods of teaching medical ethics did not show substantial changes. “Basic principles of bioethics” is the best knowledge to develop student’s reasoning analysis in medical ethics In this study, we investigate the effects of an additional small group discussion in basic principles of bioethics conventional lecture methods to cognitive achievement and retention. This study was a randomized controlled trial with parallel design. Cognitive scores of the basic principles of bioethics as a parameter was measured using basic principles of bioethics (Kaidah Dasar Bioetika, KDB test. Both groups were attending conventional lectures, then the intervention group got an additional small group discussion.Result Conventional lectures with or without small group discussion significantly increased cognitive achievement of basic principles of bioethics (P= 0.001 and P= 0.000, respectively, and there were significant differences in cognitive achievement and retention between the 2 groups (P= 0.000 and P= 0.000, respectively.Conclusion Additional small group discussion method improved cognitive achievement and retention of basic principles of bioethics. (Med J Indones 2009; 18: 48-52Keywords: lecture, specification checklist, multiple choice questions

  15. THINKING ALOUD, TALKING, AND LEAThinking aloud, talking, and learning to read: esl reading comprehension training in small cooperative groups Thinking aloud, talking, and learning to read: esl reading comprehension training in small cooperative groups

    Directory of Open Access Journals (Sweden)

    Yael Bejanaro


    Full Text Available Training students to become independent skillful readers is a major concern of the EFL reading teacher. How can we best train students in selecting and applying reading strategies so that they become more efficient readers? Can we ensure that an increase in students’ awareness of the need to use strategies will help them become more skillful readers? These questions served as a trigger for this study. The aim of this study was to investigate whether verbal articulation of reading behavior in a small group will improve foreign language comprehension. It is our contention that using verbalization in small groups will raise metacognitive awareness which will in turn enhance effective use of skills and strategies and result in improvement in reading comprehension. We assume that the special features that characterize small group interactions can provide an appropriate setting for raising metacognitive awareness. Training students to become independent skillful readers is a major concern of the EFL reading teacher. How can we best train students in selecting and applying reading strategies so that they become more efficient readers? Can we ensure that an increase in students’ awareness of the need to use strategies will help them become more skillful readers? These questions served as a trigger for this study. The aim of this study was to investigate whether verbal articulation of reading behavior in a small group will improve foreign language comprehension. It is our contention that using verbalization in small groups will raise metacognitive awareness which will in turn enhance effective use of skills and strategies and result in improvement in reading comprehension. We assume that the special features that characterize small group interactions can provide an appropriate setting for raising metacognitive awareness.

  16. Profitability recent open stock funds in Brazil: analysis of the performance of a management Funds Group active in relation to management fees charged for resource managers

    Directory of Open Access Journals (Sweden)

    Sergio Ricardo Mendes Vasconcelos


    Full Text Available This paper aimed to evaluate the performance of a specific group of active management equity investments funds relating it to the management fees charged by managers in order to answer the following research problem: open equity funds with active management, that charge higher management fees, are those that provide the best returns for the investor? The objective was to test the hypothesis under which it is evident that the funds that charged the highest rates are those with the best performances evaluated according to the average yield of the last five years. To achieve this objective, a study of descriptive nature was carried out with a quantitative approach having as object of study the profitability of Brazilian Equity Fund ranked by the Brazilian Association of Financial and Capital Markets (Anbima as IBX Active Equity Funds in the period 2010 to 2014. The analyzed returns were calculated from the Information ratio index, which measures the risk-adjusted return of the asset class. The study found no correlation between the performance of the funds and charged management fees.

  17. Among friends: the role of academic-preparedness diversity in individual performance within a small-group STEM learning environment (United States)

    Micari, Marina; Van Winkle, Zachary; Pazos, Pilar


    In this study, we investigate the relationship between academic-preparedness diversity within small learning groups and individual academic performance in science, technology, engineering, and mathematics (STEM) university courses. We further examine whether academic-preparedness diversity impacts academically more- and less-prepared students differently. We use data from 5367 university students nested within 1141 science, engineering, and mathematics learning groups and use a regression analysis to estimate the effect of group diversity, measured in two ways, on course performance. Our results indicate that academic-preparedness diversity is generally associated with positive learning outcomes, that academically less-prepared students derive greater benefit, and that less-prepared students fare best when they are not alone in a group of highly prepared students. Implications for teaching and small-group facilitation are addressed.

  18. Estimating cohesion in small groups using audio-visual nonverbal behavior

    NARCIS (Netherlands)

    Hung, H.; Gatica-Perez, D.


    Cohesiveness in teams is an essential part of ensuring the smooth running of task-oriented groups. Research in social psychology and management has shown that good cohesion in groups can be correlated with team effectiveness or productivity, so automatically estimating group cohesion for team

  19. An Analysis of Small Group Interactions of Vietnamese Students under the Bourdieusian Theoretical Lens (United States)

    Pham, Thanh; Pham, Lam


    Group work has been increasingly encouraged and applied in Vietnamese universities. However, very little has been known about how Vietnamese university students work in a group and what the conditions are that help establish an effective group. This study attempted to redress this gap. The research applied Bourdieu's social field theory to examine…

  20. The role of water and K + ion in the charge transfer between PO4- groups of DNA and the lysine + and arginine + side chains of histone proteins (United States)

    Bende, A.; Bogár, F.; Ladik, J.


    We have calculated the charge transfer (CT) between the PO4- group of DNA and the lysine (Lys) and arginine (Arg) positive side chains of histones in presence of water and K + ions. The calculations were performed at the HF + MP2 level, using the TZVP basis set. The calculations were corrected for basis set superposition error and besides Mulliken's population analysis we have introduced the - for charged systems more reliable - natural population analysis. The results show that the bare PO4--Lys and the PO4--Arg interactions become weaker, mainly, due to the presence of the K + ion. We have found 0.067 e CT for Lys and 0.050 e for Arg.

  1. Factors Affecting the Management of Women Groups' Micro and Small Enterprises in Kakamega District, Kenya (United States)

    Wawire, Nelson H. W.; Nafukho, Fredrick M.


    Purpose: The purpose of this study is to highlight the main factors that affect the management of the WGs' Micro and Small Enterprises (MSEs) in Kakamega District and Africa in general. Design/methodology/approach: The study adopted a descriptive research design. This is because the study was concerned about a univariate question in which the…

  2. Development of active learning modules in pharmacology for small group teaching. (United States)

    Tripathi, Raakhi K; Sarkate, Pankaj V; Jalgaonkar, Sharmila V; Rege, Nirmala N


    Current teaching in pharmacology in undergraduate medical curriculum in India is primarily drug centered and stresses imparting factual knowledge rather than on pharmacotherapeutic skills. These skills would be better developed through active learning by the students. Hence modules that will encourage active learning were developed and compared with traditional methods within the Seth GS Medical College, Mumbai. After Institutional Review Board approval, 90 second year undergraduate medical students who consented were randomized into six sub-groups, each with 15 students. Pre-test was administered. The three sub-groups were taught a topic using active learning modules (active learning groups), which included problems on case scenarios, critical appraisal of prescriptions and drug identification. The remaining three sub-groups were taught the same topic in a conventional tutorial mode (tutorial learning groups). There was crossover for the second topic. Performance was assessed using post-test. Questionnaires with Likert-scaled items were used to assess feedback on teaching technique, student interaction and group dynamics. The active and tutorial learning groups differed significantly in their post-test scores (11.3 ± 1.9 and 15.9 ± 2.7, respectively, P active learning session as interactive (vs. 37/90 students in tutorial group) and enhanced their understanding vs. 56/90 in tutorial group), aroused intellectual curiosity (47/90 students of active learning group vs. 30/90 in tutorial group) and provoked self-learning (41/90 active learning group vs. 14/90 in tutorial group). Sixty-four students in the active learning group felt that questioning each other helped in understanding the topic, which was the experience of 25/90 students in tutorial group. Nevertheless, students (55/90) preferred tutorial mode of learning to help them score better in their examinations. In this study, students preferred an active learning environment, though to pass examinations, they

  3. Children's Behaviors and Emotions in Small-Group Argumentative Discussion: Explore the Influence of Big Five Personality Factors (United States)

    Dong, Ting


    The assessment and structure of personality traits and small group learning during classroom discussions are both research fields that have undergone fast development in the past few decades. However, very few studies have investigated the relationship between individual personality characteristics and performance in discussions, especially with…

  4. A Model of Small-Group Problem-Based Learning in Pharmacy Education: Teaching in the Clinical Environment (United States)

    Khumsikiew, Jeerisuda; Donsamak, Sisira; Saeteaw, Manit


    Problem-based Learning (PBL) is an alternate method of instruction that incorporates basic elements of cognitive learning theory. Colleges of pharmacy use PBL to aid anticipated learning outcomes and practice competencies for pharmacy student. The purpose of this study were to implement and evaluate a model of small group PBL for 5th year pharmacy…

  5. The Application of Video Clips with Small Group and Individual Activities to Improve Young Learners' Speaking Performance (United States)

    Muslem, Asnawi; Mustafa, Faisal; Usman, Bustami; Rahman, Aulia


    This study investigated whether the application of video clips with small groups or with individual teaching-learning activities improved the speaking skills of young EFL learners the most; accordingly a quasi-experimental study with a pre-test, post-test design was done. The instrument used in this study was a test in the form of an oral test or…

  6. Enhancing Teacher Read Alouds with Small-Group Vocabulary Instruction for Students with Low Vocabulary in First-Grade Classrooms (United States)

    Fien, Hank; Santoro, Lana; Baker, Scott K.; Park, Yonghan; Chard, David J.; Williams, Susanna; Haria, Priti


    The purpose of the current study was to evaluate the effect of small-group instruction on the vocabulary and comprehension of first-grade students identified with low language and low vocabulary skills. Overall, 102 first-grade students scoring below the 50th percentile on relational vocabulary were blocked by classroom, matched according to…

  7. A Different Approach to Answering a Good Question: A Response to Hewes's Models of Communication Effects on Small Group Outcomes (United States)

    Bonito, Joseph A.; Sanders, Robert E.


    This article presents the authors' response to Hewes's (1986, 1996, 2009) models of communication effects on small group outcomes. As sophisticated and thoughtful as Hewes's new model is, however, the authors take issue with it. For one, there is reason to question whether his approach is feasible. For another, his models are not founded on solid…

  8. Among Friends: The Role of Academic-Preparedness Diversity in Individual Performance within a Small-Group STEM Learning Environment (United States)

    Micari, Marina; Van Winkle, Zachary; Pazos, Pilar


    In this study, we investigate the relationship between academic-preparedness diversity within small learning groups and individual academic performance in science, technology, engineering, and mathematics (STEM) university courses. We further examine whether academic-preparedness diversity impacts academically more- and less-prepared students…

  9. Intercultural Interactions of Mono-Cultural, Mono-Lingual Local Students in Small Group Learning Activities: A Bourdieusian Analysis (United States)

    Colvin, Cassandra; Fozdar, Farida; Volet, Simone


    This research examines the understandings and experiences of mono-cultural, mono-lingual local students in relation to intercultural interactions within small group learning activities at university. Bourdieu's concepts of field, habitus and capital are employed to illuminate a number of barriers to intercultural interaction. Using qualitative…

  10. A Meta-Analytic Review of Studies of the Effectiveness of Small-Group Learning Methods on Statistics Achievement (United States)

    Kalaian, Sema A.; Kasim, Rafa M.


    This meta-analytic study focused on the quantitative integration and synthesis of the accumulated pedagogical research in undergraduate statistics education literature. These accumulated research studies compared the academic achievement of students who had been instructed using one of the various forms of small-group learning methods to those who…

  11. Supporting Small-Group Learning Using Multiple Web 2.0 Tools: A Case Study in the Higher Education Context (United States)

    Laru, Jari; Naykki, Piia; Jarvela, Sanna


    In this single-case study, small groups of learners were supported by use of multiple social software tools and face-to-face activities in the context of higher education. The aim of the study was to explore how designed learning activities contribute to students' learning outcomes by studying probabilistic dependencies between the variables.…

  12. Assessing the Role of Peer Relationships in the Small Group Communication Course (United States)

    Myers, Scott A.; Shimotsu, Stephanie; Byrnes, Kerry; Frisby, Brandi N.; Durbin, James; Loy, Brianna N.


    Based on the typology posited by Kram and Isabella (1985) that identifies three peer relationships present in organizations (i.e., information, collegial, and special), this assessment examined the association between students' perceptions of their in-class group members and six group outcomes (i.e., grouphate, cohesion, relational satisfaction,…

  13. Need for Cognition and Active Information Search in Small Student Groups (United States)

    Curseu, Petru Lucian


    In a sample of 213 students organized in 44 groups this study tests the impact of need for cognition on active information search by using a multilevel analysis. The results show that group members with high need for cognition seek more advice in task related issues than those with low need for cognition and this pattern of information exchange is…

  14. 45 CFR 146.150 - Guaranteed availability of coverage for employers in the small group market. (United States)


    ... SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS REQUIREMENTS FOR THE GROUP HEALTH INSURANCE MARKET... (and their dependents) or any health status-related factor relating to those employees and dependents... status-related factor relating to those employees and dependents. (2) An issuer that denies group health...

  15. Examining the Effect of Small Group Discussions and Question Prompts on Vicarious Learning Outcomes (United States)

    Lee, Yekyung; Ertmer, Peggy A.


    This study investigated the effect of group discussions and question prompts on students' vicarious learning experiences. Vicarious experiences were delivered to 65 preservice teachers via VisionQuest, a Web site that provided examples of successful technology integration. A 2x2 factorial research design employed group discussions and question…

  16. Administrative Leadership in Three Small, Private Tennessee Colleges: Working Groups, Real Teams, or Both? (United States)

    Nichols, Michael E.


    Diversity of knowledge and multiple perspectives are characteristic advantages of group leadership as compared to transactional or bureaucratic forms of leadership. When groups are engaged in administrative functions, they are more likely to realize a higher level of performance and more relevant and innovative solutions than may be achieved by a…

  17. Power and status within small groups: An analysis of students' verbal and nonverbal behavior and responses to one another (United States)

    Morris, Lynnae Carol

    The purpose of this research has been to determine the influence of verbal and nonverbal behavior on power and status within small groups. The interactions which took place within five small groups of students in a middle school spatial reasoning elective were analyzed. Verbal responses to requests for help were analyzed using sequential analysis techniques. Results indicated that the identity of the student asking a question or requesting help in some form or another is a better predictor of whether he/she will receive help than the type of questions he/she asks. Nonverbal behavior was analyzed for social gestures, body language, and shifts in possession of tools. Each nonverbal act was coded as either "positive" (encouraging participation) or "negative" (discouraging participation); and, the researchers found that in groups in which there was unequal participation and less "help" provided among peers (according to the verbal analysis results) there tended to be more "negative" nonverbal behavior demonstrated than in groups in which "shared talk time" and "helping behavior" were common characteristics of the norm. The combined results from the analyses of the verbal and nonverbal behavior of students within small groups were then reviewed through the conflict, power, status perspective of small group interactions in order to determine some common characteristics of high functioning (collaborative) and low functioning (non-collaborative) groups. Some common characteristics of the higher functioning groups include: few instances of conflict, shared "talk time" and decision making, inclusive leadership, frequent use of encouraging social gestures and body language, and more sharing of tools than seizing. Some shared traits among the lower functioning groups include: frequent occurrences of interpersonal conflict, a focus on process (rather than content), persuasive or alienating leadership, unequal participation and power, frequent use of discouraging social gestures

  18. Report of the advisory group meeting on elemental analysis of extremely small samples

    International Nuclear Information System (INIS)


    This publication contains summary of discussions held at the meeting with brief description and comparative characteristics of most common nuclear analytical techniques used for analysis of very small samples as well as the conclusions of the meeting. Some aspect of reference materials and quality control are also discussed. The publication also contains individual contributions made by the participants, each of these papers haven provided with an abstract and indexed separately

  19. Two-Stage Battery Energy Storage System (BESS in AC Microgrids with Balanced State-of-Charge and Guaranteed Small-Signal Stability

    Directory of Open Access Journals (Sweden)

    Bing Xie


    Full Text Available In this paper, a two-stage battery energy storage system (BESS is implemented to enhance the operation condition of conventional battery storage systems in a microgrid. Particularly, the designed BESS is composed of two stages, i.e., Stage I: integration of dispersed energy storage units (ESUs using parallel DC/DC converters, and Stage II: aggregated ESUs in grid-connected operation. Different from a conventional BESS consisting of a battery management system (BMS and power conditioning system (PCS, the developed two-stage architecture enables additional operation and control flexibility in balancing the state-of-charge (SoC of each ESU and ensures the guaranteed small-signal stability, especially in extremely weak grid conditions. The above benefits are achieved by separating the control functions between the two stages. In Stage I, a localized power sharing scheme based on the SoC of each particular ESU is developed to manage the SoC and avoid over-charge or over-discharge issues; on the other hand, in Stage II, an additional virtual impedance loop is implemented in the grid-interactive DC/AC inverters to enhance the stability margin with multiple parallel-connected inverters integrating at the point of common coupling (PCC simultaneously. A simulation model based on MATLAB/Simulink is established, and simulation results verify the effectiveness of the proposed BESS architecture and the corresponding control diagram.

  20. The Impact of Molecular p-Doping on Charge Transport in High-Mobility Small-Molecule/Polymer Blend Organic Transistors

    KAUST Repository

    Paterson, Alexandra F.


    Molecular doping is a powerful tool with the potential to resolve many of the issues currently preventing organic thin-film transistor (OTFT) commercialization. However, the addition of dopant molecules into organic semiconductors often disrupts the host lattice, introducing defects and harming electrical transport. New dopant-based systems that overcome practical utilization issues, while still reaping the electrical performance benefits, would therefore be extremely valuable. Here, the impact of p-doping on the charge transport in blends consisting of the small-molecule 2,7-dioctyl[1]benzothieno[3,2-b][1]benzothiophene (C8-BTBT), the polymer indacenodithiophene-benzothiadiazole (C16IDT-BT), and the molecular dopant C60F48 is investigated. Electrical field-effect measurements indicate that p-doping not only enhances the average saturation mobility from 1.4 to 7.8 cm2 V−1 s−1 over 50 devices (maximum values from around 4 to 13 cm2 V−1 s−1), but also improves bias–stress stability, contact resistance, threshold voltage, and the overall device-to-device performance variation. Importantly, materials characterization using X-ray diffraction, X-ray photoemission spectroscopy, and ultraviolet photoemission spectroscopy, combined with charge transport modeling, reveal that effective doping is achieved without perturbing the microstructure of the polycrystalline semiconductor film. This work highlights the remarkable potential of ternary organic blends as a simple platform for OTFTs to achieve all the benefits of doping, with none of the drawbacks.

  1. Learning science in small groups: The relationship of conversation to conceptual understanding (United States)

    McDonald, James Tarleton

    The purpose of this study was to investigate the relationship between conversation and conceptual understanding of erosion. The objective of this study was to investigate how fifth grade students' conceptions of erosion changed while they used stream tables and worked in groups of four within an inquiry-based curriculum. This study used symbolic interactionism and sociocognitive frameworks to interpret science learning in the elementary classroom. The research focused on the conceptual understanding of the focal group students, their use of classroom discourse to talk about their understandings of erosion, and the expertise that emerged while using stream tables. This study took place over a one-semester long study on erosion. Key informants were eight fifth graders. The data sources consisted of children's journals; transcripts of audiotaped interviews with the key informants before, during, and after the erosion unit; transcripts of videotapes of the students using the stream tables; and field notes recording children's discourse and activity. Individual and group cases were constructed during the study. The knowledge of the eight focal group children was placed on a hierarchy of conceptual understanding that contained 8 components of the erosion process. All four of the students whose ideas were examined in depth gained in their conceptual understanding of erosion. Students' individual expertise enhanced their own conceptual understanding. The contribution of classroom discourse and expertise to conceptual understanding differed between the two focal groups. Group 1 used essential expertise to sustain generative conversations, maximizing their learning opportunities. Students in Group 1 got along with one another, rotated assigned roles and jobs, and were able to start their own generative conversations. Members of Group 1 asked generative questions, connected stream table events to real life situations, and involved everyone in the group. Group 2 engaged in a

  2. Online Self-Tracking Groups to Increase Fruit and Vegetable Intake: A Small-Scale Study on Mechanisms of Group Effect on Behavior Change. (United States)

    Meng, Jingbo; Peng, Wei; Shin, Soo Yun; Chung, Minwoong


    between a focal participant and his/her group members during the experiment), such that participants who had a low performance discrepancy from other group members had greater fruit and vegetable consumption than participants who had a high performance discrepancy from other group members (P=.002). A mediation test showed that low performance discrepancy led to greater downward contrast (b=-0.78, 95% CI -2.44 to -0.15), which in turn led to greater fruit and vegetable consumption. Online self-tracking groups were more effective than self-tracking alone in promoting fruit and vegetable consumption for early young adults. Low performance discrepancy from other group members lead to downward contrast, which in turn increased participants' fruit and vegetable consumption over time. The study highlighted social comparison processes in online groups that allow for sharing personal health information. Lastly, given the small scale of this study, nonsignificant results with small effect sizes might be subject to bias. ©Jingbo Meng, Wei Peng, Soo Yun Shin, Minwoong Chung. Originally published in the Journal of Medical Internet Research (, 06.03.2017.

  3. Expeditionary Strike Group: New Label, or New Concept - for Future Naval Warriors of America's Small Wars?

    National Research Council Canada - National Science Library

    Hancock, Daryl


    ... as, emergent contingency operations, and major theater wars. In the near future they will accomplish this mission while deployed around the globe under the new concept of Expeditionary Strike Groups (ESG...

  4. Quantitative Modeling of Membrane Transport and Anisogamy by Small Groups Within a Large-Enrollment Organismal Biology Course

    Directory of Open Access Journals (Sweden)

    Eric S. Haag


    Full Text Available Quantitative modeling is not a standard part of undergraduate biology education, yet is routine in the physical sciences. Because of the obvious biophysical aspects, classes in anatomy and physiology offer an opportunity to introduce modeling approaches to the introductory curriculum. Here, we describe two in-class exercises for small groups working within a large-enrollment introductory course in organismal biology. Both build and derive biological insights from quantitative models, implemented using spreadsheets. One exercise models the evolution of anisogamy (i.e., small sperm and large eggs from an initial state of isogamy. Groups of four students work on Excel spreadsheets (from one to four laptops per group. The other exercise uses an online simulator to generate data related to membrane transport of a solute, and a cloud-based spreadsheet to analyze them. We provide tips for implementing these exercises gleaned from two years of experience.

  5. Educational Outcomes of Small-Group Discussion Versus Traditional Lecture Format in Dental Students' Learning and Skills Acquisition. (United States)

    Arias, Ana; Scott, Raymond; Peters, Ove A; McClain, Elizabeth; Gluskin, Alan H


    The aim of this prospective quantitative study was to compare the effect of different instructional formats on dental students' skills and knowledge acquisition for access cavity preparation. All first-year dental students were invited to participate in this study conducted during the four consecutive two-week endodontic rotation courses at the University of the Pacific Arthur A. Dugoni School of Dentistry in spring semester 2015. Four alphabetically distributed intact groups of students were randomly allocated to two groups (n=70 each) that participated in either small-group discussion or a traditional lecture on access preparation. The first outcome measure was skill acquisition, measured by the quality of access cavities prepared in extracted teeth at the conclusion of the session. Two blinded raters scored direct observations on a continuous scale. Knowledge, the second outcome measure, was scored with a multiple-choice and open-ended question test at the end of each two-week session. Data were obtained for 134 of the 140 students, for a 96% response rate. The results showed that students in the small-group discussion groups scored significantly higher than those in the lecture groups when skill performance was tested (p=8.9 × 10(-7)). However, no significant differences were found in the acquisition of knowledge between the two groups on the written test. Active student participation was significantly related to improved manual skill acquisition, but the format of the session does not seem to have had a direct influence on acquired knowledge.

  6. Scottish pharmacists' perceptions and experiences of a practice-based small group learning pilot: a qualitative study. (United States)

    Cunningham, David E; Zlotos, Leon; Power, Ailsa


    CPD is an important feature of healthcare professions and regulatory bodies consider it mandatory. Studies of CPD activity of pharmacists showed that 10% were undertaking no CPD. Practice-based small group learning (PBSGL) is a well-received and popular learning resource for GPs in Scotland. From 2011, a pharmacy pilot was undertaken: pharmacists were trained as peer-facilitators and existing PBSGL modules were adapted. Four NHS boards took part and this study aimed to explore the perceptions and experiences of pharmacists. A qualitative research approach was adopted using focus groups and in-depth interviews. Interviews were audio-recorded and transcriptions made. Transcripts were coded and themes developed using grounded theory methods. Participants welcomed PBSGL: it was a feasible learning method, acceptable and had educational impact. They appreciated its interactive nature and discussions founded on their experiences in practice. Participants liked the self-reliance of PBSGL in that they were not dependent on specialist practitioners. There were logistical challenges that impacted on the success of group discussion; some pharmacists were less familiar with small group work. Pharmacists felt isolated during work and appreciated peer discussion. There was a tentative welcome to inter-professional learning but group composition and module topics might impact on the success of this. Pharmacists were able to change their learning practice in uni-professional PBSGL groups and were able to learn from each other. There may be further learning opportunities if pharmacists participate in inter-professional groups.

  7. Student recognition of visual affordances: Supporting use of physics simulations in whole class and small group settings (United States)

    Stephens, A. Lynn

    The purpose of this study is to investigate student interactions with simulations, and teacher support of those interactions, within naturalistic high school physics classroom settings. This study focuses on data from two lesson sequences that were conducted in several physics classrooms. The lesson sequences were conducted in a whole class discussion format in approximately half of the class sections and in a hands-on-computer small group format in matched class sections. Analysis used a mixed methods approach where: (1) quantitative methods were used to evaluate pre-post data; (2) open coding and selective coding were used for transcript analysis; and (3) comparative case studies were used to consider the quantitative and qualitative data in light of each other and to suggested possible explanations. Although teachers expressed the expectation that the small group students would learn more, no evidence was found in pre-post analysis for an advantage for the small group sections. Instead, a slight trend was observed in favor of the whole class discussion sections, especially for students in the less advanced sections. In seeking to explain these results, qualitative analyses of transcript and videotape data were conducted, revealing that many more episodes of support for interpreting visual elements of the simulations occurred in the whole class setting than in the matched small group discussions; not only teachers, but, at times, students used more visual support moves in the whole class discussion setting. In addition, concepts that had been identified as key were discussed for longer periods of time in the whole class setting than in the matched small group discussions in six of nine matched sets. For one of the lesson sequences, analysis of student work on in-class activity sheets identified no evidence that any of the Honors or College Preparatory students in the small groups had made use in their thinking of the key features of the sophisticated and popular

  8. A Rapid Review of the Factors Affecting Healthcare Students' Satisfaction with Small-Group, Active Learning Methods. (United States)

    Kilgour, James M; Grundy, Lisa; Monrouxe, Lynn V


    PHENOMENON: Problem-based learning (PBL) and other small-group, active learning methodologies have been widely adopted into undergraduate and postgraduate healthcare curricula across the world. Although much research has examined student perceptions of these innovative teaching pedagogies, there are still questions over which factors influence these views. This article aims to identify these key elements that affect healthcare student satisfaction with PBL and other small-group learning methods, including case-based and team-based learning. A systematic rapid review method was used to identify high-quality original research papers from the healthcare education literature from between 2009 and 2014. All papers were critically appraised before inclusion in line with published guidelines. Narrative synthesis was achieved using an inductively developed, thematic framework approach. Fifty-four papers were included in the narrative synthesis. The evidence suggests that, despite an initial period of negative emotion and anxiety, the perspectives of healthcare students toward small-group, active learning methods are generally positive. The key factors influencing this satisfaction level include (a) the facilitator role, (b) tutorial structure, (c) individual student factors, (d) case authenticity, (e) increased feedback, (f) group harmony, and (g) resource availability. Insights: Student satisfaction is an important determinant of healthcare education quality, and the findings of this review may be of value in future curriculum design. The evidence described here suggests that an ideal curriculum may be based on an expert-led, hybrid PBL model.

  9. Small Group Dynamics and the Watergate Coverup: A Case Study of Groupthink. (United States)

    Cline, Rebecca J.

    The decisions President Richard Nixon and his closest advisors made in the Watergate coverup were products of what Irving Janis calls "groupthink." Groupthink, a type of decision-making emphasizing unanimity over objective evaluation, develops when the decision makers (1) form a group of marked cohesiveness, (2) insulate themselves from…

  10. Can't You Just Talk to Them? Small Group Work in a Senior Thesis Course. (United States)

    Nance, Teresa; Mackey-Kallis, Susan

    At Villanova University, the Senior Projects Course is designed to serve as a capstone course. Students are required to integrate the pieces of the discipline acquired from previous course work into a comprehensive, fully developed research project. This paper looks critically at one aspect of effectively managing a group project course: conflict…

  11. On the suitability of group lending model in South Sudan's small and ...

    African Journals Online (AJOL)

    The success of this mode of SME funding in selected jurisdictions, namely Angola, Bangladesh, Bolivia, Burundi, and Colombia underscores such a position. The socio-economic, legal and political environment of the three jurisdictions studied in this paper where group lending has been successful closely mirror that of ...

  12. Small groups, large profits: Calculating interest rates in community-managed microfinance

    DEFF Research Database (Denmark)

    Rasmussen, Ole Dahl


    , it is impossible to compare returns in savings groups with returns elsewhere. Moreover, the interest on savings is incomparable to the interest rate on loans. I argue for the use of a standardized comparable metric and suggest easy ways to implement it. Developments of new tools and standard along these lines...

  13. The Multiple Family Group as a Small Society: Fitting Theory and Method. (United States)

    Reiss, David; And Others

    This is a comprehensive report of a study of the mechanisms by which the family regulates its interaction with the immediate social environment. Subjects were four multiple family groups, each composed of six or more families, meeting in both hospital and home settings. In each family, at least one member was either an alcoholic or an adolescent…

  14. Lurking on the Internet: A Small-Group Assignment that Puts a Human Face on Psychopathology (United States)

    Lowman, Joseph; Judge, Abigail M.; Wiss, Charles


    Lurking on the Internet aims to put a human face on psychopathology for the abnormal psychology course. Student groups are assigned major diagnostic categories and instructed to search the Internet for discussion forums, individual blogs, or YouTube videos where affected individuals discuss their symptoms and lives. After discussing the ethics of…

  15. Informal Cooperative Learning in Small Groups: The Effect of Scaffolding on Participation (United States)

    Lange, Christopher; Costley, Jamie; Han, Seung Lock


    This study examines the effect of group work scaffolding on participation. The procedural scaffolding of two cooperative learning techniques, Numbered Heads Together and Think-Pair-Share, are compared based on levels of participation, learning, and satisfaction they elicit. Aspects of participation that are examined include levels of group…

  16. The economic efficiency of investment in the development of reserves of small groups of geographically contiguous gold deposits

    Directory of Open Access Journals (Sweden)

    Evdokimov S.I.


    Full Text Available The object of the research is a group of geographically contiguous low volume gold deposits. The subject of the study is an economic justification for a way to involve economic turnover to get a positive commercial result on a specially formed group of gold deposits, in which individual field development is unprofitable. A small production volume, combined with high capital and operating costs are objective reasons for the reduction in investment attractiveness of the deposits which have reserves of gold of 50%, equipped with a mobile processing complex with deep processing technology on highly liquid commodity products on site. An economic-mathematical model was devised to determine the rational placement of the processing capacity of the group.A simulation was conducted and an economic evaluation was performed on the effectiveness of investments in individual and group mining projects. The simulation results show that the joint exploitation of the reserves of the group of deposits, the internal rate of return on investments exceed the rate of return of funds to the bank deposit, the return on investment is above the level of inflation. The group project complies with the strategic line of small mining companies in terms of cost recovery terms, availability of financial sources to cover expenses, provision of stable means of income and obtaining competitive advantage.

  17. Applying information theory to small groups assessment: emotions and well-being at work. (United States)

    García-Izquierdo, Antonio León; Moreno, Blanca; García-Izquierdo, Mariano


    This paper explores and analyzes the relations between emotions and well-being in a sample of aviation personnel, passenger crew (flight attendants). There is an increasing interest in studying the influence of emotions and its role as psychosocial factors in the work environment as they are able to act as facilitators or shock absorbers. The contrast of the theoretical models by using traditional parametric techniques requires a large sample size to the efficient estimation of the coefficients that quantify the relations between variables. Since the available sample that we have is small, the most common size in European enterprises, we used the maximum entropy principle to explore the emotions that are involved in the psychosocial risks. The analyses show that this method takes advantage of the limited information available and guarantee an optimal estimation, the results of which are coherent with theoretical models and numerous empirical researches about emotions and well-being.

  18. A collaborative working environment for small group meetings in Second Life. (United States)

    da Silva, Cintia Rc; Garcia, Ana Cristina B


    This paper presents the SLMeetingRoom, a virtual reality online environment to support group meetings of geographically dispersed participants. A prototype was developed to demonstrate the feasibility of the approach using the Second Life platform. Ten additional components had to be added to Second Life environment to support group work essential activities such as participants' communication, tasks' and participants' coordination, participants' collaboration and work evolution's perception. Empirical studies, both pilot and experiment, were developed comparing four different meeting settings: face-to-face, videoconference, stand Second Life and SLMeetingRoom. The study involved graduate students enrolled in the Interface and Multimedia discipline at the Fluminense Federal University (UFF) in Brazil. Results indicated that groups working within SLMeetingRoom environment presented similar results as face-to-face meeting as far as sense of presence is concerned and with low cognitive effort. Task completion and degree of participation were not affected by the meeting set up. It was concluded that Second Life, in conjunction with the SLMeetingRoom components, is a good tool for holding synchronous remote meetings and coexists with other electronic meeting technologies.

  19. From fused aromatics to graphene-like nanoribbons: The effects of multiple terminal groups, length and symmetric pathways on charge transport

    KAUST Repository

    Bilić, Ante


    A class of molecular ribbons, with almost-ideal charge transmission, that is weakly dependent on the anchoring structure or electrode crystalline orientation and easy to synthesize has been identified. Charge transport through two sets of aromatic nanoribbons, based on the pyrene and perylene motifs, has been investigated using density functional theory combined with the nonequilibrium Green\\'s function method. The effects of wire length and multiple terminal thiolate groups at the junction with gold leads have been examined. For the oligopyrene series, an exponential drop in the conductance with the increase of the wire length is found. In contrast, the oligoperylene series of nanoribbons, with dual thiolate groups, exhibits no visible length dependence, indicating that the contacts are the principal source of the resistance. Between the Au(001) leads, the transmission spectra of the oligoperylenes display a continuum of highly conducting channels and the resulting conductance is nearly independent of the bias. The predictions are robust against artefacts from the exchange-correlation potential, as evidenced from the self-interaction corrected calculations. Therefore, oligoperylene nanoribbons show the potential to be the almost-ideal wires for molecular circuitry. © 2011 American Physical Society.

  20. Long-term evolution of the S788 fungal nuclear small subunit rRNA group I introns




    More than 1000 group I introns have been identified in fungal rDNA. Little is known, however, of the splicing and secondary structure evolution of these ribozymes. Here, we use a combination of comparative and biochemical methods to address the evolution and splicing of a vertically inherited group I intron found at position 788 in the fungal small subunit (S) rRNA. The ancestral state of the S788 intron contains a highly conserved core and an extended P5 domain typical of IC1 introns. In con...


    Aguayo, Joseph; Regeczkey, Agnes


    The authors historically situate the London Kleinian development in terms of the small-group collaborations and adversaries that arose during the course of Melanie Klein's career. Some collaborations later became personally adversarial (e.g., those Klein had with Glover and Schmideberg); other adversarial relationships forever remained that way (with A. Freud); while still other long-term collaborations became theoretically contentious (such as with Winnicott and Heimann). After the Controversial Discussions in 1944, Klein marginalized one group of supporters (Heimann, Winnicott, and Riviere) in favor of another group (Rosenfeld, Segal, and Bion). After Klein's death in 1960, Bion maintained loyalty to Klein's ideas while quietly distancing his work from the London Klein group, immigrating to the United States in 1968. © 2016 The Psychoanalytic Quarterly, Inc.

  2. Level one algebraic cusp forms of classical groups of small rank

    CERN Document Server

    Chenevier, Gaëtan


    The authors determine the number of level 1, polarized, algebraic regular, cuspidal automorphic representations of \\mathrm{GL}_n over \\mathbb Q of any given infinitesimal character, for essentially all n \\leq 8. For this, they compute the dimensions of spaces of level 1 automorphic forms for certain semisimple \\mathbb Z-forms of the compact groups \\mathrm{SO}_7, \\mathrm{SO}_8, \\mathrm{SO}_9 (and {\\mathrm G}_2) and determine Arthur's endoscopic partition of these spaces in all cases. They also give applications to the 121 even lattices of rank 25 and determinant 2 found by Borcherds, to level o

  3. Just forest governance: how small learning groups can have big impact

    Energy Technology Data Exchange (ETDEWEB)

    Mayers, James; Bhattacharya, Prodyut; Diaw, Chimere [and others


    Forests are power bases, but often for the wrong people. As attention turns from making an international deal on REDD to making it work on the ground, the hunt will be on for practical ways of shifting power over forests towards those who enable and pursue sustainable forest-linked livelihoods. The Forest Governance Learning Group – an alliance active in Cameroon, Ghana, India, Indonesia, Malawi, Mozambique, South Africa, Uganda and Vietnam – has developed practical tactics for securing safe space, provoking dialogue, building constituencies, wielding evidence and interacting politically. It has begun to have significant impacts. To deepen and widen those impacts, FGLG seeks allies.

  4. History of the evaluation and exploitation of a group of small uranium mines in Portugal

    International Nuclear Information System (INIS)

    Cameron, J.


    In the period 1945-1962 a multiple small-scale uranium mining project was successfully operated in Portugal by the Companhia Portuguesa de Radium Lda, the Urgeirica Mine and some 28 smaller mines produced ore between 1951 and 1962 and provided uranium concentrates for export under an agreement between the Portugal, the United Kingdom and the United States Governments. The uranium deposits occur in near-vertical fractures in the granites of the Beiras mostly having a NE-SW strike trend. The veins are the siliceous-pyrite-galena type with red jasper and black and white quartz gangue and much wall rock alternation and shearing. The primary uranium mineral is pitchblende and the secondary minerals tobernite and autunite occur in the near-surface zones. Of the 63 concessions controlled in 1945, the Urgeirica Mine, dating from the radium period, was by far the biggest, but by mid-1946, after a very rapid preliminary evaluation, it was concluded that a total ''possible'' ore reserve of 1080 tons U 3 O 8 might exist in the concessions. On this basis an agreement was reached with the Portuguese Government for the production and export of between 120 and 150 t U 3 O 8 per year for a twelve-year period up to the end of 1962, and for a maximum of 1325 t U 3 O 8 . Production commenced on a regular basis at the beginning of 1952 and the total production quota of 1325 t U 3 O 8 was produced by 31 March 1962

  5. Adsorption of carbon monoxide on small aluminum oxide clusters: Role of the local atomic environment and charge state on the oxidation of the CO molecule (United States)

    Ornelas-Lizcano, J. C.; Guirado-López, R. A.


    We present extensive density functional theory (DFT) calculations dedicated to analyze the adsorption behavior of CO molecules on small AlxOy± clusters. Following the experimental results of Johnson et al. [J. Phys. Chem. A 112, 4732 (2008)], we consider structures having the bulk composition Al2O3, as well as smaller Al2O2 and Al2O units. Our electron affinity and total energy calculations are consistent with aluminum oxide clusters having two-dimensional rhombus-like structures. In addition, interconversion energy barriers between two- and one-dimensional atomic arrays are of the order of 1 eV, thus clearly defining the preferred isomers. Single CO adsorption on our charged AlxOy± clusters exhibits, in general, spontaneous oxygen transfer events leading to the production of CO2 in line with the experimental data. However, CO can also bind to both Al and O atoms of the clusters forming aluminum oxide complexes with a CO2 subunit. The vibrational spectra of AlxOy + CO2 provides well defined finger prints that may allow the identification of specific isomers. The AlxOy+ clusters are more reactive than the anionic species and the final Al2O+ + CO reaction can result in the production of atomic Al and carbon dioxide as observed from experiments. We underline the crucial role played by the local atomic environment, charge density distribution, and spin-multiplicity on the oxidation behavior of CO molecules. Finally, we analyze the importance of coadsorption and finite temperature effects by performing DFT Born-Oppenheimer molecular dynamics. Our calculations show that CO oxidation on AlxOy+ clusters can be also promoted by the binding of additional CO species at 300 K, revealing the existence of fragmentation processes in line with the ones experimentally inferred.

  6. Introduction of small and medium reactors in developing countries. Proceedings of two advisory group meetings

    International Nuclear Information System (INIS)


    This publication presents material submitted both by vendor and interested buyer organizations and conclusions drawn from the discussions of these contributions at two Advisory Group meetings on the SMR introduction in developing countries. A few papers were prepared as follow-up contributions to the proceedings. The summary presents a review of the main areas related to SMR introduction and of relevant situations and activities in both industrialized and developing countries. It includes an assessment of the expected potential market and of relevant experience that may help developing countries in their efforts to introduce SMRs. Owing to the inclusion of several new designs, this TECDOC provides an update of the SMR status report (IAEA-TECDOC-881) published in 1996. It also reviews real time compact nuclear power plant simulators

  7. Novel Emergency Medicine Curriculum Utilizing Self-Directed Learning and the Flipped Classroom Method: Gastrointestinal Emergencies Small Group Module

    Directory of Open Access Journals (Sweden)

    Andrew King


    Full Text Available Audience and type of curriculum: This curriculum created and implemented at The Ohio State University Wexner Medical Center was designed to educate our emergency medicine (EM residents, PGY-1 to PGY-3, as well as medical students and attending physicians. Introduction/Background: Gastrointestinal (GI emergencies comprise approximately 12% of emergency department (ED visits.1 Residents must be proficient in the differential diagnosis and management of the wide variety of GI emergencies. The flipped classroom curricular model emphasizes self-directed learning activities completed by learners, followed by small group discussions pertaining to the topic reviewed. The active learning fostered by this curriculum increases faculty and learner engagement and interaction time typically absent in traditional lecture-based formats.2-4 Studies have revealed that the application of knowledge through case studies, personal interaction with content experts, and integrated questions are effective learning strategies for emergency medicine residents.4-6 The Ohio State University EM Residency didactic curriculum recently transitioned to a “flipped classroom” approach.7-10 We created this innovative curriculum aimed to improve our residency education program and to share educational resources with other EM residency programs. This proposed curriculum utilizes an 18-month curricular cycle. The flipped classroom curriculum maximizes didactic time and resident engagement, fosters intellectual curiosity and active learning, and meets the needs of today’s learners. 3,6,11 Objectives: We aim to teach the presentation and management of GI emergencies through the creation of a flipped classroom design. This unique, innovative curriculum utilizes resources chosen by education faculty and resident learners, study questions, real-life experiences, and small group discussions in place of traditional lectures. In doing so, a goal of the curriculum is to encourage self

  8. Novel Emergency Medicine Curriculum Utilizing Self-Directed Learning and the Flipped Classroom Method: Genitourinary Emergencies Small Group Module

    Directory of Open Access Journals (Sweden)

    Andrew King


    Full Text Available Audience: This curriculum, created and implemented at The Ohio State University Wexner Medical Center, was designed to educate our emergency medicine (EM residents, PGY-1 to PGY-3, as well as medical students. Introduction: In 2013, there were over 6 million Emergency Department visits in the United States which resulted in a primary diagnosis of the genitourinary system. This represents 5.2% of all Emergency Department visits.1 Residents must be proficient in the differential diagnosis and management of the wide variety of genitourinary emergencies. This flipped classroom curricular model emphasizes self-directed learning activities completed by learners, followed by small group discussions pertaining to the topic reviewed. The active learning fostered by this curriculum increases faculty and learner engagement and interaction time typically absent in traditional lecture-based formats.2-4 Studies have revealed that the application of knowledge through case studies, personal interaction with content experts, and integrated questions are effective learning strategies for emergency medicine residents.4-6 The Ohio State University Wexner Medical Center EM Residency didactic curriculum recently transitioned to a “flipped classroom” approach.7-10 We created this innovative curriculum aimed to improve our residency education program and to share educational resources with other EM residency programs. Our curriculum utilizes an 18-month curricular cycle to cover the defined emergency medicine content. The flipped classroom curriculum maximizes didactic time and resident engagement, fosters intellectual curiosity and active learning, and meets the needs of today’s learners. 3,6,11 Objectives: We aim to teach the presentation and management of genitourinary emergencies through the creation of a flipped classroom design. This unique, innovative curriculum utilizes resources chosen by education faculty and resident learners, study questions, real

  9. Genomic selection accuracies within and between environments and small breeding groups in white spruce. (United States)

    Beaulieu, Jean; Doerksen, Trevor K; MacKay, John; Rainville, André; Bousquet, Jean


    Genomic selection (GS) may improve selection response over conventional pedigree-based selection if markers capture more detailed information than pedigrees in recently domesticated tree species and/or make it more cost effective. Genomic prediction accuracies using 1748 trees and 6932 SNPs representative of as many distinct gene loci were determined for growth and wood traits in white spruce, within and between environments and breeding groups (BG), each with an effective size of Ne ≈ 20. Marker subsets were also tested. Model fits and/or cross-validation (CV) prediction accuracies for ridge regression (RR) and the least absolute shrinkage and selection operator models approached those of pedigree-based models. With strong relatedness between CV sets, prediction accuracies for RR within environment and BG were high for wood (r = 0.71-0.79) and moderately high for growth (r = 0.52-0.69) traits, in line with trends in heritabilities. For both classes of traits, these accuracies achieved between 83% and 92% of those obtained with phenotypes and pedigree information. Prediction into untested environments remained moderately high for wood (r ≥ 0.61) but dropped significantly for growth (r ≥ 0.24) traits, emphasizing the need to phenotype in all test environments and model genotype-by-environment interactions for growth traits. Removing relatedness between CV sets sharply decreased prediction accuracies for all traits and subpopulations, falling near zero between BGs with no known shared ancestry. For marker subsets, similar patterns were observed but with lower prediction accuracies. Given the need for high relatedness between CV sets to obtain good prediction accuracies, we recommend to build GS models for prediction within the same breeding population only. Breeding groups could be merged to build genomic prediction models as long as the total effective population size does not exceed 50 individuals in order to obtain high prediction accuracy such as that

  10. Building life-long learning capacity in undergraduate nursing freshmen within an integrative and small group learning context. (United States)

    Chiang, Vico C L; Leung, Sharron S K; Chui, Caroline Y Y; Leung, Angela Y M; Mak, Y W


    Life-long learning involves the development of skills in critical thinking (CT), effective group process (GP), and self-directedness (SDL). Recent studies have shown that small group learning with active interactions is effective in enabling students to develop themselves as independent learners beyond graduation. With a view to integrative learning, the purpose of this study was to evaluate life-long learning outcomes through the work of small group teaching and learning for a class of undergraduate nursing freshmen during one academic year. A mixed-methods approach was used to evaluate the CT, GP and SDL of 99 freshmen with a self-assessment questionnaire before and after their learning activities in three nursing courses, and to identify themes from a total of six focus group interviews with the students and teachers. The CT, GP and SDL results obtained from self-assessment did not indicate significant differences. Four themes emerged from the qualitative analysis. Many factors contributed to the results on life-long learning skill development of students in this study. The qualitative analysis provided good insights for future teaching and learning development. With a developmental perspective, life-long learning may be better developed and evaluated over a longer period of time in the nursing program. Copyright © 2012 Elsevier Ltd. All rights reserved.

  11. ssDNA Pairing Accuracy Increases When Abasic Sites Divide Nucleotides into Small Groups.

    Directory of Open Access Journals (Sweden)

    Alexandra Peacock-Villada

    Full Text Available Accurate sequence dependent pairing of single-stranded DNA (ssDNA molecules plays an important role in gene chips, DNA origami, and polymerase chain reactions. In many assays accurate pairing depends on mismatched sequences melting at lower temperatures than matched sequences; however, for sequences longer than ~10 nucleotides, single mismatches and correct matches have melting temperature differences of less than 3°C. We demonstrate that appropriately grouping of 35 bases in ssDNA using abasic sites increases the difference between the melting temperature of correct bases and the melting temperature of mismatched base pairings. Importantly, in the presence of appropriately spaced abasic sites mismatches near one end of a long dsDNA destabilize the annealing at the other end much more effectively than in systems without the abasic sites, suggesting that the dsDNA melts more uniformly in the presence of appropriately spaced abasic sites. In sum, the presence of appropriately spaced abasic sites allows temperature to more accurately discriminate correct base pairings from incorrect ones.

  12. Small-Group Learning in an Upper-Level University Biology Class Enhances Academic Performance and Student Attitudes Toward Group Work (United States)

    Nakonechny, Joanne; Cragg, Jacquelyn J.; Ramer, Matt S.


    To improve science learning, science educators' teaching tools need to address two major criteria: teaching practice should mirror our current understanding of the learning process; and science teaching should reflect scientific practice. We designed a small-group learning (SGL) model for a fourth year university neurobiology course using these criteria and studied student achievement and attitude in five course sections encompassing the transition from individual work-based to SGL course design. All students completed daily quizzes/assignments involving analysis of scientific data and the development of scientific models. Students in individual work-based (Individualistic) sections usually worked independently on these assignments, whereas SGL students completed assignments in permanent groups of six. SGL students had significantly higher final exam grades than Individualistic students. The transition to the SGL model was marked by a notable increase in 10th percentile exam grade (Individualistic: 47.5%; Initial SGL: 60%; Refined SGL: 65%), suggesting SGL enhanced achievement among the least prepared students. We also studied student achievement on paired quizzes: quizzes were first completed individually and submitted, and then completed as a group and submitted. The group quiz grade was higher than the individual quiz grade of the highest achiever in each group over the term. All students – even term high achievers –could benefit from the SGL environment. Additionally, entrance and exit surveys demonstrated student attitudes toward SGL were more positive at the end of the Refined SGL course. We assert that SGL is uniquely-positioned to promote effective learning in the science classroom. PMID:21209910

  13. Taking charge of epilepsy: the development of a structured psychoeducational group intervention for adolescents with epilepsy and their parents. (United States)

    Snead, Kara; Ackerson, Joseph; Bailey, Kirstin; Schmitt, Margaret M; Madan-Swain, Avi; Martin, Roy C


    Children and adolescents with epilepsy frequently experience poor psychosocial outcomes due to numerous factors such as perceived stigma, behavior problems, academic difficulties, and depression. Health psychology research has documented the effectiveness of psychoeducational interventions aimed at improving psychosocial outcomes for individuals with a variety of health conditions. With increasing numbers of adolescents living with epilepsy, interest in improving the quality of life for this particular population has grown. There remains, however, a paucity of research concerning psychosocial interventions for adolescents with epilepsy. The present study outlines the development and initial implementation of a 6-week structured psychoeducational group intervention for adolescents with epilepsy and their parents. Preintervention, the QOLIE-AD-48, Childhood Depression Inventory, and Revised Children's Manifest Anxiety Scale were administered. Educational topics included medical aspects of epilepsy, healthy lifestyle behaviors, family and peer relationships, understanding self-image and self-esteem, and stress management techniques. Participants were introduced to a variety of cognitive-behavioral strategies, and were encouraged to share their own experiences with epilepsy. Feedback from adolescent and parent participants indicated that the intervention was relevant to their needs, helped them better understand their epilepsy, and allowed an opportunity for positive peer support. Also, postintervention outcome measurement indicated an overall positive trend for quality of life improvement in the adolescents.

  14. xGASS: gas-rich central galaxies in small groups and their connections to cosmic web gas feeding (United States)

    Janowiecki, Steven; Catinella, Barbara; Cortese, Luca; Saintonge, Amélie; Brown, Toby; Wang, Jing


    We use deep H I observations obtained as part of the extended GALEX Arecibo SDSS survey (xGASS) to study the cold gas properties of central galaxies across environments. We find that below stellar masses of 1010.2 M⊙, central galaxies in groups have an average atomic hydrogen gas fraction ˜0.3 dex higher than those in isolation at the same stellar mass. At these stellar masses, group central galaxies are usually found in small groups of N = 2 members. The higher H I content in these low-mass group central galaxies is mirrored by their higher average star formation activity and molecular hydrogen content. At larger stellar masses, this difference disappears and central galaxies in groups have similar (or even smaller) gas reservoirs and star formation activity compared to those in isolation. We discuss possible scenarios able to explain our findings and suggest that the higher gas content in low-mass group central galaxies is likely due to the contributions from the cosmic web or H I-rich minor mergers, which also fuel their enhanced star formation activity.

  15. Setting the question for inquiry: The effects of whole class vs small group on student achievement in elementary science (United States)

    Cavagnetto, Andy Roy

    This study was conducted to determine the effects of two different student-centered approaches to setting the question for inquiry. The first approach (whole class) consisted of students setting a single question for inquiry after which students worked in small groups during an investigation phase of the activity with all groups exploring the same question. The second approach (small group) consisted of each group of students setting a question resulting in numerous questions being explored per class. A mixed method quasi-experimental design was utilized. Two grade five teachers from a small rural school district in the Midwestern United States participated, each teaching two sections of science (approximately 25 students per section). Results indicate three major findings. Instructional approach (whole class vs. small group) did not effect student achievement in science or language arts. Observational data indicated the actions and skills teachers utilized to implement the approaches were similar. Specifically, the pedagogical skills of dialogical interaction (which was found to be influenced by teacher level of control of learning and teacher content knowledge) and effective rather than efficient use of time were identified as key factors in teachers' progression toward a student-centered, teacher-managed instructional approach. Unit exams along with qualitative and quantitative teacher observation data indicated that these factors do have an impact on student achievement. Specifically increased dialogical interaction in the forms of greater student voice, and increased cognitive demands placed on students by embedding and emphasizing science argument within the student inquiry corresponded to positive gains in student achievement. Additionally, teacher's perception of student abilities was also found to influence professional growth. Finally, allowing students to set the questions for inquiry and design the experiments impact the classroom environment as teacher

  16. Classical local U(1 gauge invariance in Weyl 2-spinor lenguage and charge quantization from irreducible representations of the gauge group

    Directory of Open Access Journals (Sweden)

    J. Buitrago

    Full Text Available A new classical 2-spinor approach to U(1 gauge theory is presented in which the usual four-potential vector field is replaced by a symmetric second rank spinor. Following a lagrangian formulation, it is shown that the four-rank spinor representing the Maxwell field tensor has a U(1 local gauge invariance in terms of the electric and magnetic field strengths. When applied to the magnetic field of a monopole, this formulation, via the irreducible representation condition for the gauge group, leads to a quantization condition differing by a factor 2 of the one predicted by Dirac without relying on any kind of singular vector potentials. Finally, the U(1 invariant spinor equations, are applied to electron magnetic resonance which has many applications in the study of materials. Keywords: Weyl 2-spinor lenguage, Dirac equation, Gauge theories, Charge quantization

  17. Photofragment Coincidence Imaging of Small I- (H2O)n Clusters Excited to the Charge-transfer-to-solvent State

    Energy Technology Data Exchange (ETDEWEB)

    Neumark, D. E. Szpunar, K. E. Kautzman, A. E. Faulhaber, and D. M.; Kautzman, K.E.; Faulhaber, A.E.; Faulhaber, A.E.


    The photodissociation dynamics of small I{sup -}(H{sub 2}O){sub n} (n = 2-5) clusters excited to their charge-transfer-to-solvent (CTTS) states have been studied using photofragment coincidence imaging. Upon excitation to the CTTS state, two photodissociation channels were observed. The major channel ({approx}90%) is a 2-body process forming neutral I + (H{sub 2}O){sub n} photofragments, and the minor channel is a 3-body process forming I + (H{sub 2}O){sub n-1} + H{sub 2}O fragments. Both process display translational energy (P(E{sub T})) distributions peaking at E{sub T} = 0 with little available energy partitioned into translation. Clusters excited to the detachment continuum rather than to the CTTS state display the same two channels with similar P(E{sub T}) distributions. The observation of similar P(E{sub T}) distributions from the two sets of experiments suggests that in the CTTS experiments, I atom loss occurs after autodetachment of the excited (I(H{sub 2}O){sub n}{sup -})* cluster, or, less probably, that the presence of the excess electron has little effect on the departing I atom.

  18. Problem-based, small-group tutorial learning in clinical neurology for second-year medical students. (United States)

    Yu, H Y; Wu, Z A; Su, M S; Yen, D J; Luk, H R; Chao, Y C; Liao, K K; Lin, K P; Yu, S M; Liu, H C


    Problem-based learning (PBL) in small-group tutorials has been a trend in medical education. Chinese students are known to be reserved and passive; thus, they may not be adaptable to PBL. Neuroanatomy, important to clinical neurology, is difficult to learn. We incorporated clinical neurology with PBL, complementary to the traditional neuroanatomy curriculum, to evaluate the feasibility of PBL for Chinese students in Taiwan. Forty-two second-year medical students and seven tutors participated in the clinical neurology PBL small-group tutorials. Twelve case reports were discussed weekly beginning in February, 1999. Each case was designed to meet the progressive curriculum of the neuroanatomy course. The tutors evaluated the students by the degree of their preparation, participation, key-point comprehension and interaction. All tutors and students filled out questionnaires at the end of each session. The majority of the students and tutors agreed that the case materials were clearly written. Ninety percent of the students agreed that the case materials matched the traditional content of neuroanatomy. Eighty-five percent of students and 71% of tutors were satisfied and found the class rewarding. Ninety-one percent of students and 74% of tutors were in favor of PBL being continued. This preliminary PBL, small-group tutorial learning in clinical neurology showed satisfactory results and was, indeed, complementary to a traditional neuroanatomy course. The students, as early as during the second year of their medical school education, were able to learn through the PBL. More integration of basic and clinical sciences by PBL may be considered in future curricula designs.

  19. Small Groups: Student Productive Interactions in Learning Cooperative (Case Study of Mathematics Learning at Junior High School in Pakis, Malang

    Directory of Open Access Journals (Sweden)

    Katarina Tri Utaminingtyas


    Full Text Available The purpose of this study is to describe the process of student interaction in solving problems through cooperative learning. The subject of this research are 7th grade students of a junior high school in Malang, Indonesia. Data were collected by recording directly when learning takes place especially when pairing or forming small groups. This interaction is built with heterogeneous student skills. The results showed that the interaction that occurs in students provides an understanding of the concept of opportunity. Consequently, the students solved the problem correctly. This interaction is known as productive interaction.

  20. Small Ubiquitin-like Modifier (SUMO) Conjugation Impedes Transcriptional Silencing by the Polycomb Group Repressor Sex Comb on Midleg*


    Smith, Matthew; Mallin, Daniel R.; Simon, Jeffrey A.; Courey, Albert J.


    The Drosophila protein Sex Comb on Midleg (Scm) is a member of the Polycomb group (PcG), a set of transcriptional repressors that maintain silencing of homeotic genes during development. Recent findings have identified PcG proteins both as targets for modification by the small ubiquitin-like modifier (SUMO) protein and as catalytic components of the SUMO conjugation pathway. We have found that the SUMO-conjugating enzyme Ubc9 binds to Scm and that this interaction, which requires the Scm C-te...

  1. Affective Balance, Team Prosocial Efficacy and Team Trust: A Multilevel Analysis of Prosocial Behavior in Small Groups (United States)

    Cuadrado, Esther; Tabernero, Carmen


    Little research has focused on how individual- and team-level characteristics jointly influence, via interaction, how prosocially individuals behave in teams and few studies have considered the potential influence of team context on prosocial behavior. Using a multilevel perspective, we examined the relationships between individual (affective balance) and group (team prosocial efficacy and team trust) level variables and prosocial behavior towards team members. The participants were 123 students nested in 45 small teams. A series of multilevel random models was estimated using hierarchical linear and nonlinear modeling. Individuals were more likely to behave prosocially towards in-group members when they were feeling good. Furthermore, the relationship between positive affective balance and prosocial behavior was stronger in teams with higher team prosocial efficacy levels as well as in teams with higher team trust levels. Finally, the relevance of team trust had a stronger influence on behavior than team prosocial efficacy. PMID:26317608

  2. Occupational Safety and Health Conditions Aboard Small- and Medium-Size Fishing Vessels: Differences among Age Groups. (United States)

    Zytoon, Mohamed A; Basahel, Abdulrahman M


    Although marine fishing is one of the most hazardous occupations, research on the occupational safety and health (OSH) conditions aboard marine fishing vessels is scarce. For instance, little is known about the working conditions of vulnerable groups such as young and aging fishermen. The objective of the current paper is to study the OSH conditions of young and aging fishermen compared to middle-aged fishermen in the small- and medium-size (SM) marine fishing sector. A cross-sectional study was designed, and 686 fishermen working aboard SM fishing vessels were interviewed to collect information about their safety and health. The associations of physical and psychosocial work conditions with safety and health outcomes, e.g., injuries, illnesses and job satisfaction, are presented. The results of the current study can be utilized in the design of effective accident prevention and OSH training programs for the three age groups and in the regulation of working conditions aboard fishing vessels.

  3. Pore Polarity and Charge Determine Differential Block of Kir1.1 and Kir7.1 Potassium Channels by Small-Molecule Inhibitor VU590. (United States)

    Kharade, Sujay V; Sheehan, Jonathan H; Figueroa, Eric E; Meiler, Jens; Denton, Jerod S


    VU590 was the first publicly disclosed, submicromolar-affinity (IC 50 = 0.2 μ M), small-molecule inhibitor of the inward rectifier potassium (Kir) channel and diuretic target, Kir1.1. VU590 also inhibits Kir7.1 (IC 50 ∼ 8 μ M), and has been used to reveal new roles for Kir7.1 in regulation of myometrial contractility and melanocortin signaling. Here, we employed molecular modeling, mutagenesis, and patch clamp electrophysiology to elucidate the molecular mechanisms underlying VU590 inhibition of Kir1.1 and Kir7.1. Block of both channels is voltage- and K + -dependent, suggesting the VU590 binding site is located within the pore. Mutagenesis analysis in Kir1.1 revealed that asparagine 171 (N171) is the only pore-lining residue required for high-affinity block, and that substituting negatively charged residues (N171D, N171E) at this position dramatically weakens block. In contrast, substituting a negatively charged residue at the equivalent position in Kir7.1 enhances block by VU590, suggesting the VU590 binding mode is different. Interestingly, mutations of threonine 153 (T153) in Kir7.1 that reduce constrained polarity at this site (T153C, T153V, T153S) make wild-type and binding-site mutants (E149Q, A150S) more sensitive to block by VU590. The Kir7.1-T153C mutation enhances block by the structurally unrelated inhibitor VU714 but not by a higher-affinity analog ML418, suggesting that the polar side chain of T153 creates a barrier to low-affinity ligands that interact with E149 and A150. Reverse mutations in Kir1.1 suggest that this mechanism is conserved in other Kir channels. This study reveals a previously unappreciated role of membrane pore polarity in determination of Kir channel inhibitor pharmacology. Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics.

  4. The role of prophylactic cranial irradiation in regionally advanced non-small cell lung cancer. A Southwest Oncology Group Study

    International Nuclear Information System (INIS)

    Rusch, V.W.; Griffin, B.R.; Livingston, R.B.


    Lung cancer is the most common malignant disease in the United States. Only the few tumors detected very early are curable, but there has been some progress in the management of more advanced non-small cell lung cancer, particularly in regionally inoperable disease. Prevention of central nervous system relapse is an important issue in this group of patients because brain metastases ultimately develop in 20% to 25% of them. Seventy-three patients with regionally advanced non-small cell lung cancer were entered into a Phase II trial of neutron chest radiotherapy sandwiched between four cycles of chemotherapy including cisplatin, vinblastine, and mitomycin C. Prophylactic cranial irradiation was administered concurrently with chest radiotherapy (3000 cGy in 10 fractions in 15 patients; 3600 cGy in 18 fractions in the remaining 50 patients). Patients underwent computed tomographic scan of the brain before treatment and every 3 months after treatment. The initial overall response rate was 79%, but 65 of the 73 patients have subsequently died of recurrent disease. Median follow-up is 9 months for all 73 patients and 26 months for eight long-term survivors. No patient who completed the prophylactic cranial irradiation program had clinical or radiologic brain metastases. Toxic reactions to prophylactic cranial irradiation included reversible alopecia in all patients, progressive dementia in one patient, and possible optic neuritis in one patient. Both of these patients received 300 cGy per fraction of irradiation. The use of prophylactic cranial irradiation has been controversial, but its safety and efficacy in this trial supports its application in a group of patients at high risk for central nervous system relapse. Further evaluation of prophylactic cranial irradiation in clinical trials for regionally advanced non-small cell lung cancer is warranted

  5. The role of prophylactic cranial irradiation in regionally advanced non-small cell lung cancer. A Southwest Oncology Group Study

    Energy Technology Data Exchange (ETDEWEB)

    Rusch, V.W.; Griffin, B.R.; Livingston, R.B. (Univ. of Washington, Seattle (USA))


    Lung cancer is the most common malignant disease in the United States. Only the few tumors detected very early are curable, but there has been some progress in the management of more advanced non-small cell lung cancer, particularly in regionally inoperable disease. Prevention of central nervous system relapse is an important issue in this group of patients because brain metastases ultimately develop in 20% to 25% of them. Seventy-three patients with regionally advanced non-small cell lung cancer were entered into a Phase II trial of neutron chest radiotherapy sandwiched between four cycles of chemotherapy including cisplatin, vinblastine, and mitomycin C. Prophylactic cranial irradiation was administered concurrently with chest radiotherapy (3000 cGy in 10 fractions in 15 patients; 3600 cGy in 18 fractions in the remaining 50 patients). Patients underwent computed tomographic scan of the brain before treatment and every 3 months after treatment. The initial overall response rate was 79%, but 65 of the 73 patients have subsequently died of recurrent disease. Median follow-up is 9 months for all 73 patients and 26 months for eight long-term survivors. No patient who completed the prophylactic cranial irradiation program had clinical or radiologic brain metastases. Toxic reactions to prophylactic cranial irradiation included reversible alopecia in all patients, progressive dementia in one patient, and possible optic neuritis in one patient. Both of these patients received 300 cGy per fraction of irradiation. The use of prophylactic cranial irradiation has been controversial, but its safety and efficacy in this trial supports its application in a group of patients at high risk for central nervous system relapse. Further evaluation of prophylactic cranial irradiation in clinical trials for regionally advanced non-small cell lung cancer is warranted.

  6. Traffic represents the main source of pollution in small Mediterranean urban areas as seen by lichen functional groups. (United States)

    Llop, Esteve; Pinho, Pedro; Ribeiro, Manuel C; Pereira, Maria João; Branquinho, Cristina


    The land-use type (residential, green areas, and traffic) within relatively small Mediterranean urban areas determines significant changes on lichen diversity, considering species richness and functional groups related to different ecological factors. Those areas with larger volume of traffic hold lower species diversity, in terms of species richness and lichen diversity value (LDV). Traffic areas also affect the composition of the lichen community, which is evidenced by sensitive species. The abundance of species of lichens tolerant to low levels of eutrophication diminishes in traffic areas; oppositely, those areas show a higher abundance of species of lichens tolerating high levels of eutrophication. On the other hand, residential and green areas have an opposite pattern, mainly with species highly tolerant to eutrophication being less abundant than low or moderate ones. The characteristics of tree bark do not seem to affect excessively on lichen composition; however, tree species shows some effect that should be considered in further studies.

  7. Single case design studies in music therapy: resurrecting experimental evidence in small group and individual music therapy clinical settings. (United States)

    Geist, Kamile; Hitchcock, John H


    The profession would benefit from greater and routine generation of causal evidence pertaining to the impact of music therapy interventions on client outcomes. One way to meet this goal is to revisit the use of Single Case Designs (SCDs) in clinical practice and research endeavors in music therapy. Given the appropriate setting and goals, this design can be accomplished with small sample sizes and it is often appropriate for studying music therapy interventions. In this article, we promote and discuss implementation of SCD studies in music therapy settings, review the meaning of internal study validity and by extension the notion of causality, and describe two of the most commonly used SCDs to demonstrate how they can help generate causal evidence to inform the field. In closing, we describe the need for replication and future meta-analysis of SCD studies completed in music therapy settings. SCD studies are both feasible and appropriate for use in music therapy clinical practice settings, particularly for testing effectiveness of interventions for individuals or small groups. © the American Music Therapy Association 2014. All rights reserved. For permissions, please e-mail:


    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jungha; Lee, Jeong-Eun [School of Space Research, Kyung Hee University, Yongin-Si, Gyeonggi-Do 446-701 (Korea, Republic of); Choi, Minho; Kang, Miju [Korea Astronomy and Space Science Institute, 776 Daedeokdaero, Yuseong, Daejeon 305-348 (Korea, Republic of); Bourke, Tyler L. [Square Kilometre Array Organisation, Jodrell Bank Observatory, Lower Withington, Cheshire SK11 9DL (United Kingdom); II, Neal J. Evans [Department of Astronomy, University of Texas at Austin, 2515 Speedway, Stop C1400, Austin, TX 78712-1205 (United States); Francesco, James Di [National Research Council Canada, Herzberg Institute of Astrophysics, Victoria, BC (Canada); Cieza, Lucas A. [Universidad Diego Portales, Facultad de Ingeniera, Av. Ejército 441, Santiago (Chile); Dunham, Michael M. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States)


    We present a multi-wavelength observational study of a low-mass star-forming region, L1251-C, with observational results at wavelengths from the near-infrared to the millimeter. Spitzer Space Telescope observations confirmed that IRAS 22343+7501 is a small group of protostellar objects. The extended emission in the east–west direction with its intensity peak at the center of L1251A has been detected at 350 and 850 μm with the Caltech Submillimeter Observatory and James Clerk Maxwell telescopes, tracing dense envelope material around L1251A. The single-dish data from the Korean VLBI Network and TRAO telescopes show inconsistencies between the intensity peaks of several molecular emission lines and that of the continuum emission, suggesting complex distributions of molecular abundances around L1251A. The Submillimeter Array interferometer data, however, show intensity peaks of CO 2–1 and {sup 13}CO 2–1 located at the position of IRS 1, which is both the brightest source in the Infrared Array Camera image and the weakest source in the 1.3 mm dust-continuum map. IRS 1 is the strongest candidate for the driving source of the newly detected compact CO 2–1 outflow. Over the entire region (14′ × 14′) of L125l-C, 3 Class I and 16 Class II sources have been detected, including three young stellar objects (YSOs) in L1251A. A comparison between the average projected distance among the 19 YSOs in L1251-C and that among the 3 YSOs in L1251A suggests that L1251-C is an example of low-mass cluster formation where protostellar objects form in a small group.

  9. DFT Study of Electronic and Optical Properties of Small Oligothiophenes Based on Terthiophene End-capped by Several Donor Groups

    Directory of Open Access Journals (Sweden)

    El Alamy Aziz


    Full Text Available Eight small molecules based on terthiophene end-capped by several donor groups have been carried out using density functional theory (DFT and time-dependent (TDDFT methods in neutral and doped states. The theoretical ground-state geometry, electronic structure and optical properties of the studied molecules were obtained by the DFT and TD-DFT methods at the B3LYP level with 6-31G(d basis set. Theoretical knowledge of the highest occupied molecular orbital (HOMO, the lowest unoccupied molecular orbital (LUMO energy levels the gap energy (Eg and the open-circuit voltage (Voc of the studied compounds are calculated and discussed. The effects of the donor group substituents on the geometries and optoelectronic properties of these materials are discussed to investigate the relationship between molecular structure and optoelectronic properties. The results of this work suggest some of these materials as a good candidate for organic solar cells. DOI:

  10. Benefits of adding small financial incentives or optional group meetings to a web-based statewide obesity initiative. (United States)

    Leahey, Tricia M; Subak, Leslee L; Fava, Joseph; Schembri, Michael; Thomas, Graham; Xu, Xiaomeng; Krupel, Katie; Kent, Kimberly; Boguszewski, Katherine; Kumar, Rajiv; Weinberg, Brad; Wing, Rena


    To examine whether adding either small, variable financial incentives or optional group sessions improves weight losses in a community-based, Internet behavioral program. Participants (N = 268) from Shape Up Rhode Island 2012, a 3-month Web-based community wellness initiative, were randomized to: Shape Up+Internet behavioral program (SI), Shape Up+Internet program+incentives (SII), or Shape Up+Internet program+group sessions (SIG). At the end of the 3-month program, SII achieved significantly greater weight losses than SI (SII: 6.4% [5.1-7.7]; SI: 4.2% [3.0-5.6]; P = 0.03); weight losses in SIG were not significantly different from the other two conditions (SIG: 5.8% [4.5-7.1], P's ≥ 0.10). However, at the 12-month no-treatment follow-up visit, both SII and SIG had greater weight losses than SI (SII: 3.1% [1.8-4.4]; SIG: 4.5% [3.2-5.8]; SI: 1.2% [-0.1-2.6]; P's ≤ 0.05). SII was the most cost-effective approach at both 3 (SII: $34/kg; SI: $34/kg; SIG: $87/kg) and 12 months (SII: $64/kg; SI: $140/kg; SIG: $113/kg). Modest financial incentives enhance weight losses during a community campaign, and both incentives and optional group meetings improved overall weight loss outcomes during the follow-up period. However, the use of the financial incentives is the most cost-effective approach. © 2014 The Obesity Society.

  11. A path less traveled: A self-guided action science inquiry among a small group of adult learners (United States)

    Folkman, Daniel Vance

    This dissertation provides an analysis of the dialogue that occurred among a small group of adult learners who engaged in a self-guided action science inquiry into their own practice. The following pages describe how this group of five practitioners ventured into a critical, self-reflective inquiry into their own values, feelings, and intentions in search of personal and professional growth. It is a deeply revealing story that shows how, through group dialogue, the members gradually unravel the interconnections between their values, feelings, and intention. They uncover surprising and unanticipated patterns in their reasoning-in-action that reflect lessons from present day experiences as well as childhood axioms about what constitutes appropriate behavior. They push their learning further to recognize emotional triggers that are useful in confronting old habits of mind that must be overcome if new Model II strategies are to be learned and internalized. They conclude that becoming Model II requires a centering on basic values, a personal commitment to change, a willingness to persist in the face of resistance, and the wisdom to act with deliberate caution. The transformative power of this insight lies in the realization of what it takes personally and collectively to make the world a truly respectful, productive, democratic, and socially just place in which to live and work. The action science literature holds the assumption that a trained facilitator is needed to guide such an inquiry and the learning of Model II skills. Unfortunately, there are few educator-trainers available to facilitate the learning of Model II proficiencies over the months and years that may be required. The data presented here show that it is possible for a group of highly motivated individuals to initiate and sustain their own action science inquiry without the aid of a highly skilled facilitator. A model of the group dialogue is presented that highlights the salient characteristics of an

  12. Commercial Laboratory Testing of Excision Repair Cross-Complementation Group 1 Expression in Non-Small Cell Lung Cancer (United States)

    Farhadfar, Nosha; Sivapiragasam, Abirami; Geller, Matthew; Islam, Shahidul; Selbs, Elena


    Introduction. Excision repair cross-complementation group 1 (ERCC1) expression by non-small cell lung cancer (NSCLC) has been reported to predict resistance to platinum-based therapies. On this basis, several commercial laboratories have offered ERCC1 testing to facilitate clinical decision making, but the reliability of such assays has recently been called into question. Methods. First, three large commercial laboratories were queried for their cumulative ERCC1 test results in NSCLC patients to compare their independent rates of ERCC1 expression. Second, identical tumor blocks from individual NSCLC patients underwent round-robin analysis to evaluate interlaboratory concordance for ERCC1 expression. Third, a retrospective review of medical records from NSCLC patients identified those who were both highly responsive and resistant to platinum-based chemotherapies. Tumor blocks from these patients were then used in a gold standard analysis to determine individual laboratory sensitivity and specificity for ERCC1 results. Results. Significant differences were observed in independent laboratory ERRC1 expression rates (Clarient 70% vs. Genzyme 60% vs. Third Laboratory 44%, p marketed laboratory assays achieved a specificity of greater than 50%. Conclusion. The results of commercial laboratory testing for ERCC1 are inconsistent and unreliable. Better validation and postmarketing surveillance should be mandated before tumor biomarker assays are allowed to enter the clinical arena. PMID:24705979

  13. Individual and small-group market health insurance rate review and disclosure: state and federal roles after PPACA. (United States)

    Linehan, Kathryn


    Oversight of private insurance, including health insurance, is primarily a state responsibility. Each state establishes its own laws and regulations regarding insurer activities, including premium increases for the insurance products within its purview. The authority that state regulators have to review and deny requests for premium changes varies from state to state, as do the amount of resources available to state insurance departments for reviewing premium changes. In some markets where insurers have proposed or implemented steep increases, such changes have received considerable attention from the press, state regulators, and policymakers. The Patient Protection and Affordable Care Act (PPACA) requires annual review of premium increases and disclosure of those increases determined unreasonable beginning in September 2011. Under PPACA, each state will conduct these reviews for individual and small-group health insurance unless the federal government concludes they do not have an effective review program and assumes review responsibility. As they did prior to PPACA, state laws govern whether rates go into effect and establish the parameters of regulators' authority. This issue brief outlines specific state and federal roles in the rate review process and changes to rate review processes since PPACA was enacted.

  14. Small ubiquitin-like modifier (SUMO) conjugation impedes transcriptional silencing by the polycomb group repressor Sex Comb on Midleg. (United States)

    Smith, Matthew; Mallin, Daniel R; Simon, Jeffrey A; Courey, Albert J


    The Drosophila protein Sex Comb on Midleg (Scm) is a member of the Polycomb group (PcG), a set of transcriptional repressors that maintain silencing of homeotic genes during development. Recent findings have identified PcG proteins both as targets for modification by the small ubiquitin-like modifier (SUMO) protein and as catalytic components of the SUMO conjugation pathway. We have found that the SUMO-conjugating enzyme Ubc9 binds to Scm and that this interaction, which requires the Scm C-terminal sterile α motif (SAM) domain, is crucial for the efficient sumoylation of Scm. Scm is associated with the major Polycomb response element (PRE) of the homeotic gene Ultrabithorax (Ubx), and efficient PRE recruitment requires an intact Scm SAM domain. Global reduction of sumoylation augments binding of Scm to the PRE. This is likely to be a direct effect of Scm sumoylation because mutations in the SUMO acceptor sites in Scm enhance its recruitment to the PRE, whereas translational fusion of SUMO to the Scm N terminus interferes with this recruitment. In the metathorax, Ubx expression promotes haltere formation and suppresses wing development. When SUMO levels are reduced, we observe decreased expression of Ubx and partial haltere-to-wing transformation phenotypes. These observations suggest that SUMO negatively regulates Scm function by impeding its recruitment to the Ubx major PRE.

  15. Small Ubiquitin-like Modifier (SUMO) Conjugation Impedes Transcriptional Silencing by the Polycomb Group Repressor Sex Comb on Midleg* (United States)

    Smith, Matthew; Mallin, Daniel R.; Simon, Jeffrey A.; Courey, Albert J.


    The Drosophila protein Sex Comb on Midleg (Scm) is a member of the Polycomb group (PcG), a set of transcriptional repressors that maintain silencing of homeotic genes during development. Recent findings have identified PcG proteins both as targets for modification by the small ubiquitin-like modifier (SUMO) protein and as catalytic components of the SUMO conjugation pathway. We have found that the SUMO-conjugating enzyme Ubc9 binds to Scm and that this interaction, which requires the Scm C-terminal sterile α motif (SAM) domain, is crucial for the efficient sumoylation of Scm. Scm is associated with the major Polycomb response element (PRE) of the homeotic gene Ultrabithorax (Ubx), and efficient PRE recruitment requires an intact Scm SAM domain. Global reduction of sumoylation augments binding of Scm to the PRE. This is likely to be a direct effect of Scm sumoylation because mutations in the SUMO acceptor sites in Scm enhance its recruitment to the PRE, whereas translational fusion of SUMO to the Scm N terminus interferes with this recruitment. In the metathorax, Ubx expression promotes haltere formation and suppresses wing development. When SUMO levels are reduced, we observe decreased expression of Ubx and partial haltere-to-wing transformation phenotypes. These observations suggest that SUMO negatively regulates Scm function by impeding its recruitment to the Ubx major PRE. PMID:21278366

  16. Validation of a CFD model simulating charge and discharge of a small heat storage test module based on a sodium acetate water mixture

    DEFF Research Database (Denmark)

    Dannemand, Mark; Fan, Jianhua; Furbo, Simon


    Experimental and theoretical investigations are carried out to study the heating of a 302 x 302 x 55 mm test box of steel containing a sodium acetate water mixture. A thermostatic bath has been set up to control the charging and discharging of the steel box. The charging and discharging has been ...... the crystallization, ending at ambient temperature with the sodium acetate water mixture in solid phase. Comparisons have shown reasonable good agreement between experimental measurements and theoretical simulation results for the investigated scenarios....

  17. CHARGE Association

    Directory of Open Access Journals (Sweden)

    Semanti Chakraborty


    Full Text Available We present here a case of 17-year-old boy from Kolkata presenting with obesity, bilateral gynecomastia, mental retardation, and hypogonadotrophic hypogonadism. The patient weighed 70 kg and was of 153 cm height. Facial asymmetry (unilateral facial palsy, gynecomastia, decreased pubic and axillary hair, small penis, decreased right testicular volume, non-palpable left testis, and right-sided congenital inguinal hernia was present. The patient also had disc coloboma, convergent squint, microcornea, microphthalmia, pseudohypertelorism, low set ears, short neck, and choanalatresia. He had h/o VSD repaired with patch. Laboratory examination revealed haemoglobin 9.9 mg/dl, urea 24 mg/dl, creatinine 0.68 mg/dl. IGF1 77.80 ng/ml (decreased for age, GH <0.05 ng/ml, testosterone 0.25 ng/ml, FSH-0.95 ΅IU/ml, LH 0.60 ΅IU/ml. ACTH, 8:00 A.M cortisol, FT3, FT4, TSH, estradiol, DHEA-S, lipid profile, and LFT was within normal limits. Prolactin was elevated at 38.50 ng/ml. The patient′s karyotype was 46XY. Echocardiography revealed ventricularseptal defect closed with patch, grade 1 aortic regurgitation, and ejection fraction 67%. Ultrasound testis showed small right testis within scrotal sac and undescended left testis within left inguinal canal. CT scan paranasal sinuses revealed choanalatresia and deviation of nasal septum to the right. Sonomammography revealed bilateral proliferation of fibroglandular elements predominantly in subareoalar region of breasts. MRI of brain and pituitary region revealed markedly atrophic pituitary gland parenchyma with preserved infundibulum and hypothalamus and widened suprasellar cistern. The CHARGE association is an increasingly recognized non-random pattern of congenital anomalies comprising of coloboma, heart defect, choanal atresia, retarded growth and development, genital hypoplasia, ear abnormalities, and/or deafness. [1] These anomalies have a higher probability of occurring together. In this report, we have

  18. Fractional charges

    International Nuclear Information System (INIS)

    Saminadayar, L.


    20 years ago fractional charges were imagined to explain values of conductivity in some materials. Recent experiments have proved the existence of charges whose value is the third of the electron charge. This article presents the experimental facts that have led theorists to predict the existence of fractional charges from the motion of quasi-particles in a linear chain of poly-acetylene to the quantum Hall effect. According to the latest theories, fractional charges are neither bosons nor fermions but anyons, they are submitted to an exclusive principle that is less stringent than that for fermions. (A.C.)

  19. Effects of small components of 3He wave function in quasi-elastic charge exchange reaction P+3He→nF+(ppp) at intermediate energies

    International Nuclear Information System (INIS)

    Blinov, A.V.; Solov'ev, V.V.


    The contribution to the cross sections of the quasi-elastic charge-exchange reaction p+ 3 He→n p +(ppp) from the S and D components of the 3 He wave function is calculated at zero momentum transfer in the farmework of the impulse approximation taking into account the spin of the particles

  20. Effects of the surface concentration of fixed charges in C18-bonded stationary phases on the adsorption process and on the preparative chromatography of small ionizable compounds. (United States)

    Gritti, Fabrice; Guiochon, Georges


    The effects of the surface concentration of positive charges attached to the surface of research BEH-C 18 hybrid particles on the overloaded band profiles and the adsorption isotherms of a neutral (caffeine) and a positively charged (nortryptilinium hydrochloride) compounds were measured and investigated. The inverse method (IM) of chromatography was used to determine the isotherm parameters. Three columns were packed with endcapped BEH-C 18 particles doped with three different charge densities on their surfaces (LOW, MEDIUM and HIGH). Two other columns packed with unbonded, non-endcapped, and endcapped BEH-C 18 particles served as standard reference materials. Minor disturbance method (MDM) experiments were conducted with acetonitrile/water mixtures in order to assess qualitatively the surface densities of the fixed positive charges. A more quantitative approach based on the solution of the linearized Poisson-Boltzmann equation and the decrease of the experimental Henry constant was also applied. The results show that the surface concentrations of the fixed charges in the LOW, MEDIUM and HIGH columns were 0.029, 0.050, and 0.064μmol/m 2 , e.g., close to two orders of magnitude smaller than the surface density of bonded C 18 chains (2.1μmol/m 2 ). The adsorption isotherm of the ionizable compound nortryptilinium onto the BEH-C 18 columns is consistent with a two-sites adsorption model. The density of the high energy sites correlates directly to the total amount of the fixed charges and isolated silanols amidst the C 18 -bonded chains. The amount of low energy sites reflects the specific surface area of the adsorbent. The binding constants on the high- and low-energy adsorption sites are respectively ten and two times lower on the HIGH column than on the reference endcapped column. The active sites are closer to the adsorbent surface than the weak adsorption sites. Finally, a higher production rate of ionizable compounds can be achieved in preparative

  1. Evaluating effectiveness of small group information literacy instruction for Undergraduate Medical Education students using a pre- and post-survey study design. (United States)

    McClurg, Caitlin; Powelson, Susan; Lang, Eddy; Aghajafari, Fariba; Edworthy, Steven


    The Undergraduate Medical Education (UME) programme at the University of Calgary is a three-year programme with a strong emphasis on small group learning. The purpose of our study was to determine whether librarian led small group information literacy instruction, closely integrated with course content and faculty participation, but without a hands on component, was an effective means to convey EBM literacy skills. Five 15-minute EBM information literacy sessions were delivered by three librarians to 12 practicing physician led small groups of 15 students. Students were asked to complete an online survey before and after the sessions. Data analysis was performed through simple descriptive statistics. A total of 144 of 160 students responded to the pre-survey, and 112 students answered the post-survey. Instruction in a small group environment without a mandatory hands on component had a positive impact on student's evidence-based information literacy skills. Students were more likely to consult a librarian and had increased confidence in their abilities to search and find relevant information. Our study demonstrates that student engagement and faculty involvement are effective tools for delivering information literacy skills when working with students in a small group setting outside of a computer classroom. © 2015 Health Libraries Group.

  2. A Band of Sisters: The Impact of Long-Term Small Group Participation--Forty Years in a Women's Prayer and Bible Study Group (United States)

    Lawson, Kevin E.


    This article reports on a case study of a women's prayer and Bible study group that has met for over forty years. The report focuses on factors contributing to the group's longevity and vitality over time, how it changed over the years, and its impact on the lives of the women who participated in it. It also addresses how this long-term group…

  3. Markedly Increased High-Mobility Group Box 1 Protein in a Patient with Small-for-Size Syndrome

    Directory of Open Access Journals (Sweden)

    Darren G. Craig


    Full Text Available Background. Small-for-size syndrome (SFSS occurs in the presence of insufficient liver mass to maintain normal function after liver transplantation. Murine mortality following 85% hepatectomy can be reduced by the use of soluble receptor for advanced glycation end products (sRAGE to scavenge damage-associated molecular patterns and prevent their engagement with membrane-bound RAGE. Aims. To explore serum levels of sRAGE, high-mobility group box-1 (HMGB1 protein, and other soluble inflammatory mediators in a fatal case of SFSS. Methods. Serum levels of HMGB1, sRAGE, IL-18, and other inflammatory mediators were measured by ELISA in a case of SFSS, and the results were compared with 8 patients with paracetamol-induced acute liver failure (ALF and 6 healthy controls (HC. Results. HMGB1 levels were markedly higher in the SFSS patient (92.1 ng/mL compared with the ALF patients (median (IQR 11.4 (3.7–14.8 ng/mL and HC (1.42 (1.38–1.56 ng/mL. In contrast, sRAGE levels were lower in the SFSS patient (1.88 ng/mL compared with the ALF patients (3.53 (2.66–12.37 ng/mL and were similar to HC levels (1.40 (1.23–1.89 ng/mL. Conclusion. These results suggest an imbalance between pro- and anti-inflammatory innate immune pathways in SFSS. Modulation of the HMGB1-RAGE axis may represent a future therapeutic avenue in this condition.

  4. Trimodality therapy for superior sulcus non-small cell lung cancer: Southwest Oncology Group-Intergroup Trial S0220. (United States)

    Kernstine, Kemp H; Moon, James; Kraut, Michael J; Pisters, Katherine M W; Sonett, Joshua R; Rusch, Valerie W; Thomas, Charles R; Waddell, Thomas K; Jett, James R; Lyss, Alan P; Keller, Steven M; Gandara, David R


    Although preoperative chemotherapy (cisplatin-etoposide) and radiotherapy, followed by surgical resection, is considered a standard of care for superior sulcus cancers, treatment is rigorous and relapse limits long-term survival. The Southwest Oncology Group-Intergroup Trial S0220 was designed to incorporate an active systemic agent, docetaxel, as consolidation therapy. Patients with histologically proven and radiologically defined T3 to 4, N0 to 1, M0 superior sulcus non-small cell lung cancer underwent induction therapy with cisplatin-etoposide, concurrently with thoracic radiotherapy at 45 Gy. Nonprogressing patients underwent surgical resection within 7 weeks. Consolidation consisted of docetaxel every 3 weeks for 3 doses. The accrual goal was 45 eligible patients. The primary objective was feasibility. Of 46 patients registered, 44 were eligible and assessable; 38 (86%) completed induction, 29 (66%) underwent surgical resection, and 20 (45% of eligible, 69% surgical, and 91% of those initiating consolidation therapy) completed consolidation docetaxel; 28 of 29 (97%) underwent a complete (R0) resection; 2 (7%) died of adult respiratory distress syndrome. In resected patients, 21 of 29 (72%) had a pathologic complete or nearly complete response. The known site of first recurrence was local in 2, local-systemic in 1, and systemic in 10, with 7 in the brain only. The 3-year progression-free survival was 56%, and 3-year overall survival was 61%. Although trimodality therapy provides excellent R0 and local control, only 66% of patients underwent surgical resection and only 45% completed the treatment regimen. Even in this subset, distant recurrence continues to be a major problem, particularly brain-only relapse. Future strategies to improve treatment outcomes in this patient population must increase the effectiveness of systemic therapy and reduce the incidence of brain-only metastases. Copyright © 2014 The Society of Thoracic Surgeons. Published by Elsevier

  5. Evaluation of cardiac function in a group of small for gestational age school-age children treated with growth hormone. (United States)

    Aurensanz Clemente, Esther; Ayerza Casas, Ariadna; Samper Villagrasa, Pilar; Ruiz Frontera, Pablo; Bueno Lozano, Gloria


    Small for gestational age (SGA) patients have an increased risk of developing a cardiovascular pathology, as well as a metabolic syndrome. Our objective is to evaluate the cardiac morphology and function of SGA children treated with growth hormone (GH), identifying changes that could potentially have long-term consequences. We selected 23 SGA school-age patients and 23 healthy children. We measured their weight, height, blood pressure and heart rate. Using transthoracic echocardiography, we evaluated cardiac chamber size, ascending and abdominal aortic diameter as well as the systolic and diastolic function of both ventricles. SGA children have a higher systolic and diastolic blood pressure (P<.05) without significant changes in their heart rate. They also have a thicker interventricular septum (SGA Z-score 1.57 vs. 0.89; P=.026) and a worse right ventricular systolic function, with a lower TAPSE (SGA Z-score -0.98 vs. 0.95; P=.000), as well as a lower blood flow rate in the pulmonary artery (SGA 0.85m/s vs. 0.97m/s; P=.045). No significant difference was observed in the patients' left ventricular function. SGA patients' ascending aortic diameter was greater (SGA Z-score -1.09 vs. -1.93; P=.026), whereas the systolic abdominal aortic diameter was smaller (SGA Z-score-0.89 vs. -0.19; P=.015). We found functional and morphological cardiac changes in SGA school-age patients treated with GH. It is important to follow-up this patient group in order to determine if these changes contribute to an increased cardiac morbidity in adulthood. Copyright © 2016 Elsevier España, S.L.U. All rights reserved.

  6. Revealing the Value of “Green” and the Small Group with a Big Heart in Transportation Mode Choice

    Directory of Open Access Journals (Sweden)

    David Gaker


    Full Text Available To address issues of climate change, people are more and more being presented with the greenhouse gas emissions associated with their alternatives. Statements of pounds or kilograms of CO2 are showing up in trip planners, car advertisements, and even restaurant menus under the assumption that this information influences behavior. This research contributes to the literature that investigates how travelers respond to such information. Our objective is to better understand the “value of green” or how much travelers are willing to pay in money in order to reduce the CO2 associated with their travel. As with previous work, we designed and conducted a mode choice experiment using methods that have long been used to study value of time. The contributions of this paper are twofold. First, we employ revealed preference data, whereas previous studies have been based on stated preferences. Second, we provide new insight on how the value of green is distributed in the population. Whereas previous work has specified heterogeneity either systematically or with a continuous distribution, we find that a latent class choice model specification better fits the data and also is attractive behaviorally. The best fitting latent class model has two classes: one large class (76% of the sample who are not willing to spend any time or money to reduce their CO2 and a second class (24% of the sample who value reducing their CO2 at a very high rate of $2.68 per pound of reduction—our so-called small group with a big heart. We reanalyzed three datasets that we had previously collected and found considerable robustness of this two class result.

  7. Sequence type 1 group B Streptococcus, an emerging cause of invasive disease in adults, evolves by small genetic changes. (United States)

    Flores, Anthony R; Galloway-Peña, Jessica; Sahasrabhojane, Pranoti; Saldaña, Miguel; Yao, Hui; Su, Xiaoping; Ajami, Nadim J; Holder, Michael E; Petrosino, Joseph F; Thompson, Erika; Margarit Y Ros, Immaculada; Rosini, Roberto; Grandi, Guido; Horstmann, Nicola; Teatero, Sarah; McGeer, Allison; Fittipaldi, Nahuel; Rappuoli, Rino; Baker, Carol J; Shelburne, Samuel A


    The molecular mechanisms underlying pathogen emergence in humans is a critical but poorly understood area of microbiologic investigation. Serotype V group B Streptococcus (GBS) was first isolated from humans in 1975, and rates of invasive serotype V GBS disease significantly increased starting in the early 1990s. We found that 210 of 229 serotype V GBS strains (92%) isolated from the bloodstream of nonpregnant adults in the United States and Canada between 1992 and 2013 were multilocus sequence type (ST) 1. Elucidation of the complete genome of a 1992 ST-1 strain revealed that this strain had the highest homology with a GBS strain causing cow mastitis and that the 1992 ST-1 strain differed from serotype V strains isolated in the late 1970s by acquisition of cell surface proteins and antimicrobial resistance determinants. Whole-genome comparison of 202 invasive ST-1 strains detected significant recombination in only eight strains. The remaining 194 strains differed by an average of 97 SNPs. Phylogenetic analysis revealed a temporally dependent mode of genetic diversification consistent with the emergence in the 1990s of ST-1 GBS as major agents of human disease. Thirty-one loci were identified as being under positive selective pressure, and mutations at loci encoding polysaccharide capsule production proteins, regulators of pilus expression, and two-component gene regulatory systems were shown to affect the bacterial phenotype. These data reveal that phenotypic diversity among ST-1 GBS is mainly driven by small genetic changes rather than extensive recombination, thereby extending knowledge into how pathogens adapt to humans.

  8. The challenge of NSCLC diagnosis and predictive analysis on small samples. Practical approach of a working group

    DEFF Research Database (Denmark)

    Thunnissen, Erik; Kerr, Keith M; Herth, Felix J F


    Until recently, the division of pulmonary carcinomas into small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) was adequate for therapy selection. Due to the emergence of new treatment options subtyping of NSCLC and predictive testing have become mandatory. A practical approach to...

  9. Phonon and free-charge carrier properties in group-III nitride heterostructures investigated by spectroscopic ellipsometry and optical Hall effect (United States)

    Schoeche, Stefan

    The material class of group-III nitrides gained tremendous technological importance for optoelectronic and high-power/high-frequency amplification devices. Tunability of the direct band gap from 0.65 eV (InN) to 6.2 eV (AlN) by alloying, high breakthrough voltages and intrinsic mobilities, as well as the formation of highly mobile 2d electron gases (2DEG) at heterointerfaces make these compounds ideal for many applications. GaN and Ga-rich alloys are well studied and current research is mainly device-oriented. For example, choice and quality of the gate dielectric significantly influence device performance in high-electron mobility transistors (HEMT) which utilize highly mobile 2DEGs at heterointerfaces. Experimental access to the 2DEG channel properties without influence from parasitic currents or contact properties are desirable. In- and Al-rich ternary alloys are less explored than Ga-rich compounds. For InN and In-rich alloys, while many material parameters such as stiffness constants or effective mass values are largely unknown, reliable p-type doping is a major challenge, also because p-type conducting channels are buried within highly conductive n-type material formed at the surface and interfaces preventing electrical characterization. For AlN and high-Al content alloys, doping mechanisms are not understood and reliable fabrication of material with high free-charge carrier (FCC) concentrations was achieved just recently. Difficulties to form ohmic contacts impair electrical measurements and optical characterization is impeded by lack of high-energy excitation sources. In this work, spectroscopic ellipsometry over the wide spectral range from the THz to VUV in combination with optical Hall effect (generalized ellipsometry with applied magnetic field) from THz to MIR are applied in order to investigate the phonon modes and FCC properties in group-III nitride heterostructures. Adequate model descriptions and analysis strategies are introduced which allow

  10. Charge preamplifier

    International Nuclear Information System (INIS)

    Chaminade, R.; Passerieux, J.P.


    We describe a charge preamplifier having the following properties: - large open loop gain giving both stable gain and large input charge transfer; - stable input grid current with aging and without any adjustment; - fairly fast rise; - nearly optimum noise performance; - industrial material. (authors)

  11. Evaluation of Small Student-Led Discussion Groups as an Adjunct to a Course in Abnormal Psychology (United States)

    White, Geoffry D.


    Presents data related to student involvement in biweekly student-led discussion groups in an undergraduate abnormal psychology course. Evaluates the degree to which students felt they benefited from discussion groups composed of similar and dissimilar students. (Author/AV)

  12. Use of Booster Charges and Explosives in Cartridges in Underground Blasting Operations. Possibilities of Initiation of Small-Diameter Explosive Columns; Einsatz von Verstaerkungsladungen und patronierten Sprengstoffen bei der untertaegigen Sprengarbeit. Moeglichkeiten der Initiierung kleinkalibriger Ladesaeulen

    Energy Technology Data Exchange (ETDEWEB)

    Hammelmann, F.; Albrecht, T. [Orica Germany GmbH, Sprengtechnischer Dienst, Troisdorf (Germany)


    An outline of the history of industrial explosives was concluded by a description of the importance of an effective detonation chain in Glueckauf 1/2. Nowadays there are various possibilities of initiation of small-diameter explosive columns, which are encountered predominantly in the mining industry. The ignition systems and booster charges commonly used at present and also suitable for future use are described with their properties and the respective advantages and disadvantages in this contribution. The individual products are compared and evaluated. (orig.)

  13. Dynamic Measurements of Plastic Deformation in a Water-Filled Aluminum Tube in Response to Detonation of a Small Explosives Charge

    Directory of Open Access Journals (Sweden)

    Harold Sandusky


    Full Text Available Experiments have been conducted to benchmark computer code calculations for the dynamic interaction of explosions in water with structures. Aluminum cylinders with a length slightly more than twice their diameter were oriented vertically, sealed on the bottom by a thin plastic sheet, and filled with distilled water. An explosive charge suspended in the center of the tube plastically deformed but did not rupture the wall. Tube wall velocity, displacement, and strain were directly measured. The agreement among the three sets of dynamic data and the agreement of the terminal displacement measurements with the residual deformation were excellent.

  14. Interaction between heterogeneously charged surfaces: surface patches and charge modulation. (United States)

    Ben-Yaakov, Dan; Andelman, David; Diamant, Haim


    When solid surfaces are immersed in aqueous solutions, some of their charges can dissociate and leave behind charged patches on the surface. Although the charges are distributed heterogeneously on the surface, most of the theoretical models treat them as homogeneous. For overall non-neutral surfaces, the assumption of surface charge homogeneity is rather reasonable since the leading terms of two such interacting surfaces depend on the nonzero average charge. However, for overall neutral surfaces the nature of the surface charge distribution is crucial in determining the intersurface interaction. In the present work we study the interaction between two charged surfaces across an aqueous solution for several charge distributions. The analysis is preformed within the framework of the linearized Poisson-Boltzmann theory. For periodic charge distributions the interaction is found to be repulsive at small separations, unless the two surface distributions are completely out-of-phase with respect to each other. For quenched random charge distributions we find that due to the presence of the ionic solution in between the surfaces, the intersurface repulsion dominates over the attraction in the linear regime of the Poisson-Boltzmann theory. The effect of quenched charge heterogeneity is found to be particularly substantial in the case of large charged domains.

  15. Dental students\\' satisfaction of applying a combination of lecture and work in small groups compared to applying only lecture: a quasi-experimental study

    Directory of Open Access Journals (Sweden)

    Pouyan Amini Shakib


    Full Text Available Background and Aims: Choosing an appropriate style of teaching-learning by educators is a way to reach high quality education. The objective of this study conducted in Babol Dental School was to compare dental students, satisfaction of teaching theoretical general pathology course by means of a combination of lecture and work in small groups with their satisfaction of teaching the course by means of only lecture. Materials and Methods: This study was performed in the second semester of school year 2011-12 and 2012-13. In 2012 (intervention group, response rate=92%, the teaching of theoretical general pathology course was implemented by means of a combination of lecture and work in small groups, but in 2013 (control group, response rate=81% by means of only lecture. An anonymous self-administered questionnaire was used to assess students, satisfaction of the teaching methods. To compare the mean total score of satisfaction (ranging from 18 through 90 between the two groups, T-test was used. Results: Comparing the mean total scores between the two groups revealed that students, satisfaction of the combined teaching method was significantly higher (P<0.001. The difference of satisfaction between genders (separately for each group was not significant in combination group and lecture group (P=0.63 and P=0.87,   respectively. Conclusion: Regarding learning, combining lecture with other teaching methods such as work in small groups may increase health sciences students' satisfaction. In regard to teaching theoretical general pathology course, our findings could confirm this hypothesis.

  16. Understanding colloidal charge renormalization from surface chemistry: Experiment and theory (United States)

    Gisler, T.; Schulz, S. F.; Borkovec, M.; Sticher, H.; Schurtenberger, P.; D'Aguanno, B.; Klein, R.


    In this paper we report on the charging behavior of latex particles in aqueous suspensions. We use static light scattering and acid-base titrations as complementary techniques to observe both effective and bare particle charges. Acid-base titrations at various ionic strengths provide the pH dependent charging curves. The surface chemical parameters (dissociation constant of the acidic carboxylic groups, total density of ionizable sites and Stern capacitance) are determined from fits of a Stern layer model to the titration data. We find strong evidence that the dissociation of protons is the only specific adsorption process. Effective particle charges are determined by fits of integral equation calculations of the polydisperse static structure factor to the static light scattering data. A generalization of the Poisson-Boltzmann cell model including the dissociation of the acidic surface groups and the autodissociation of water is used to predict effective particle charges from the surface chemical parameters determined by the titration experiments. We find that the light scattering data are best described by a model where a small fraction of the ionizable surface sites are sulfate groups which are completely dissociated at moderate pH. These effective charges are comparable to the predictions by a basic cell model where charge regulation is absent.

  17. Standard Setting in a Small Scale OSCE: A Comparison of the Modified Borderline-Group Method and the Borderline Regression Method (United States)

    Wood, Timothy J.; Humphrey-Murto, Susan M.; Norman, Geoffrey R.


    When setting standards, administrators of small-scale OSCEs often face several challenges, including a lack of resources, a lack of available expertise in statistics, and difficulty in recruiting judges. The Modified Borderline-Group Method is a standard setting procedure that compensates for these challenges by using physician examiners and is…

  18. Novel polyfucosylated N-linked glycopeptides with blood group A, H, X and Y determinants from human small intestinal epithelial cells

    NARCIS (Netherlands)

    Vliegenthart, J.F.G.; Finne, J.; Breimer, M.E.; Hansson, G.C.; Karlsson, K.-A.; Leffler, H.; Halbeek, H. van


    A novel type of N-linked glycopeptides representing a major part of the glycans in human small intestinal epithelial cells from blood group A and O individuals were isolated by gel filtrations and affinity chromatography on concanavalin A-Sepharose and Bandeiraea simplicifolia lectin I-Sepharose.

  19. The Iterative Decision Method (IDM): Academy of Health Sciences Reports, Small Group Decision-Making and Problem-Solving Bibliography, and Statistical References. (United States)


    475. IDM Bibliography 11 * 89. James , J. A preliminary study of the size determinant in small group . interaction. American Sociological Review, 1951...Social Psydology, 1969, 12, 144-150. 109. Laughlin, P. R., & Jaccard , J. J. Social facilitation and observational learning of individuals and

  20. Perceived occupational and environmental health hazards among workers in small scale industries in Dar es Salaam, Tanzania: a focus group discussion study.

    NARCIS (Netherlands)

    Rongo, L.M.B.; Haan, S. de; Barten, F.J.M.H.; Msamanga, G.I.; Dolmans, W.M.V.; Naerssen, A.L. van; Heerderik, D.; Rongo, L.M.B.


    While the informal sector is rapidly emerging as the major source of employment in poor countries, little is known to the health hazards encountered by the workers in small-scale industries (SSI). We conducted 11 focus group discussions (FGD) among the workers in SSI to assess felt occupational

  1. Improving Executive Functions in 5- and 6-year-olds: Evaluation of a Small Group Intervention in Prekindergarten and Kindergarten Children (United States)

    Röthlisberger, Marianne; Neuenschwander, Regula; Cimeli, Patriza; Michel, Eva; Roebers, Claudia M.


    Research suggests a central role of executive functions for children's cognitive and social development during preschool years, especially in promoting school readiness. Interventions aiming to improve executive functions are therefore being called for. The present study examined the effect of a small group intervention implemented in kindergarten…

  2. Comparison of Two Small-Group Learning Methods in 12th-Grade Physics Classes Focusing on Intrinsic Motivation and Academic Performance (United States)

    Berger, Roland; Hanze, Martin


    Twelfth-grade physics classes with 344 students participated in a quasi-experimental study comparing two small-group learning settings. In the jigsaw classroom, in contrast to the cyclical rotation method, teaching expectancy as well as resource interdependence is established. The study is based on the self-determination theory of motivation,…

  3. Effects of Small-Group Tutoring with and without Validated Classroom Instruction on At-Risk Students' Math Problem Solving: Are Two Tiers of Prevention Better than One? (United States)

    Fuchs, Lynn S.; Fuchs, Douglas; Craddock, Caitlin; Hollenbeck, Kurstin N.; Hamlett, Carol L.; Schatschneider, Christopher


    This study assessed the effects of small-group tutoring with and without validated classroom instruction on at-risk students' math problem solving. Stratifying within schools, 119 3rd-grade classes were randomly assigned to conventional or validated problem-solving instruction (Hot Math, schema-broadening instruction). Students identified as at…

  4. The Effectiveness of the Smart Board-Based Small-Group Graduated Guidance Instruction on Digital Gaming and Observational Learning Skills of Children with Autism Spectrum Disorder (United States)

    Cattik, Melih; Odluyurt, Serhat


    The objective of this study was to teach digital gaming skills to children with autism spectrum disorder (ASD) using a SMART board with a graduated guidance teaching method in a small-group instructional format, to determine the participants' levels of learning by observation, and to determine the views of their families on the conducted…

  5. The "Project": Putting Student Controlled, Small Group Work and Transferable Skills at the Core of a Geography Course. (United States)

    Hindle, Brian Paul


    Describes how a cooperative group project has become a foundation of the first two years of a three-year program in college-level geography. Discusses the origin, development, and topic selection for each of the cohort groups working in the program. Asserts that the program has been favorably received by both students and faculty members. (CFR)

  6. Computer group

    International Nuclear Information System (INIS)

    Bauer, H.; Black, I.; Heusler, A.; Hoeptner, G.; Krafft, F.; Lang, R.; Moellenkamp, R.; Mueller, W.; Mueller, W.F.; Schati, C.; Schmidt, A.; Schwind, D.; Weber, G.


    The computer groups has been reorganized to take charge for the general purpose computers DEC10 and VAX and the computer network (Dataswitch, DECnet, IBM - connections to GSI and IPP, preparation for Datex-P). (orig.)

  7. More Perspectives, New Politics, New Life: How a Small Group UsedThe Integral Process For Working On Complex Issues


    Sara Ross


    This article reports on a small research project with citizens who wanted to address their community’s chronically adversarial behaviors and atmosphere. It complements a longer research report on the same project, which is also published in this issue of Integral Review. The project used a structured public discourse process, The Integral Process For Working On Complex Issues (TIP). This article supplies background on TIP’s origins, then focuses on two areas. First, it explains the process st...

  8. Prognostic Factors in Non-Small Cell Lung Cancer Less Than 3 Centimeters: Actuarial Analysis, Accumulative Incidence and Risk Groups. (United States)

    Peñalver Cuesta, Juan C; Jordá Aragón, Carlos; Mancheño Franch, Nuria; Cerón Navarro, José A; de Aguiar Quevedo, Karol; Arrarás Martínez, Miguel; Vera Sempere, Francisco J; Padilla Alarcón, Jose D


    In TNM classification, factors determining the tumor (T) component in non-small cell lung cancer have scarcely changed over time and are still based solely on anatomical features. Our objective was to study the influence of these and other morphopathological factors on survival. A total of 263 patients undergoing lung resection due to stage I non-small cell lung cancer ≤3cm in diameter were studied. A survival analysis and competing-risk estimate study was made on the basis of clinical, surgical and pathological variables using actuarial analysis and accumulative incidence methods, respectively. A risk model was then generated from the results. Survival at 5 and 10 years was 79.8 and 74.3%, respectively. The best prognostic factors were presence of symptoms, smoking habit and FEV1>60%, number of resected nodes>7, squamous histology, absence of vascular invasion, absence of visceral pleural invasion and presence of invasion more proximal than the lobar bronchus. All these were statistically significant according to the actuarial method. The factor "age60%. Pleural invasion and vascular invasion determine survival or risk of death due to non-small cell lung cancer ≤3cm and can be used for generating a predictive risk model. Copyright © 2014 SEPAR. Published by Elsevier Espana. All rights reserved.

  9. Inference With Difference-in-Differences With a Small Number of Groups: A Review, Simulation Study, and Empirical Application Using SHARE Data. (United States)

    Rokicki, Slawa; Cohen, Jessica; Fink, Günther; Salomon, Joshua A; Landrum, Mary Beth


    Difference-in-differences (DID) estimation has become increasingly popular as an approach to evaluate the effect of a group-level policy on individual-level outcomes. Several statistical methodologies have been proposed to correct for the within-group correlation of model errors resulting from the clustering of data. Little is known about how well these corrections perform with the often small number of groups observed in health research using longitudinal data. First, we review the most commonly used modeling solutions in DID estimation for panel data, including generalized estimating equations (GEE), permutation tests, clustered standard errors (CSE), wild cluster bootstrapping, and aggregation. Second, we compare the empirical coverage rates and power of these methods using a Monte Carlo simulation study in scenarios in which we vary the degree of error correlation, the group size balance, and the proportion of treated groups. Third, we provide an empirical example using the Survey of Health, Ageing, and Retirement in Europe. When the number of groups is small, CSE are systematically biased downwards in scenarios when data are unbalanced or when there is a low proportion of treated groups. This can result in over-rejection of the null even when data are composed of up to 50 groups. Aggregation, permutation tests, bias-adjusted GEE, and wild cluster bootstrap produce coverage rates close to the nominal rate for almost all scenarios, though GEE may suffer from low power. In DID estimation with a small number of groups, analysis using aggregation, permutation tests, wild cluster bootstrap, or bias-adjusted GEE is recommended.

  10. Inner-shell spectroscopy and exchange interaction of Rydberg electrons bound by singly and doubly charged Kr and Xe atoms in small clusters

    Energy Technology Data Exchange (ETDEWEB)

    Nagasaka, Masanari; Hatsui, Takaki; Setoyama, Hiroyuki; Ruehl, Eckart [Institute for Molecular Science, Myodaiji, Okazaki 444-8585 (Japan); Kosugi, Nobuhiro, E-mail: [Institute for Molecular Science, Myodaiji, Okazaki 444-8585 (Japan)


    Surface-site resolved Kr 3d{sub 5/2}{sup -1}5p and 3d{sub 5/2}{sup -1}6p and Xe 4d{sub 5/2}{sup -1}6p and 4d{sub 5/2}{sup -1}7p Rydberg excited states in small van der Waals Kr and Xe clusters with a mean size of = 15 are investigated by X-ray absorption spectroscopy. Furthermore, surface-site resolved Kr 4s{sup -2}5p, 4s{sup -2}6p, and 4s{sup -1}4p{sup -1}5p shakeup-like Rydberg states in small Kr clusters are investigated by resonant Auger electron spectroscopy. The exchange interaction of the Rydberg electron with the surrounding atoms and the induced polarization of the surrounding atoms in the singly and doubly ionized atoms are deduced from the experimental spectra to analyze different surface-site contributions in small clusters, assuming that the corner, edge, face, and bulk sites have 3, 5-6, 8, and 12 nearest neighbor atoms. These energies are almost proportional to the number of the nearest neighbor atoms. The present analysis indicates that small Kr and Xe clusters with = 15 have an average or mixture structure between the fcc-like cubic and icosahedron-like spherical structures.

  11. The Effect of Education-Based Intervention Using Small Group Discussion in Empowering Adolescent Girls to Prevent Iron Deficiency Anemia

    Directory of Open Access Journals (Sweden)

    Fatemehsadat Seyed Nematollah Roshan


    Results: At baseline, independent T-test showed no significant difference between the two groups in the perceived susceptibility, perceived severity, and self efficacy, all of which could be regarded as empowerment process components (P>0.05. However, significant differences were observed after intervention. Also, the paired T-test showed a significant difference before and after the intervention in the test group in means of the perceived susceptibility, perceived severity, self efficacy and, in the grand scheme, adolescent girls' empowerment (P

  12. Middle-school students of United Arab Emirates: effects of heterogeneous small group work on attitudes toward mathematics. (United States)

    Alkhateeb, H M; Jumaa, M


    This study compared the effects of two instructional strategies, small heterogeneous cooperative learning experience versus lecture and discussion, on students' attitudes toward mathematics. 54 boys and 57 girls in Grade 8 of four middle-school mathematics classes participated. Two classes (57 students) were taught using a cooperative learning method and the other two classes (54 students) were taught using traditional lecture and discussion. Differences between attitudes of boys and girls were also investigated and discussed in the light of Arabic culture. The results suggested that cooperative learning might be a valuable method with which to teach mathematics concepts to boys.

  13. The Skilled Use of Interaction Strategies: Creating a Framework for Improved Small-Group Communicative Interaction in the Language Classroom. (United States)

    Bejarano, Yael; And Others


    Focuses on the need to provide English-as-a-Second-Language learners with preparatory training to ensure more effective communicative interaction during group work conducted in the classroom. Findings indicate that Israeli students exposed to training in the skilled use of interaction strategies used significantly more modified-interaction and…

  14. Central model predictive control of a group of domestic heat pumps, case study for a small district

    NARCIS (Netherlands)

    van Leeuwen, Richard Pieter; Fink, J.; Smit, Gerardus Johannes Maria; Helfert, Markus; Krempels, Karl-Heinz; Donnellan, Brian; Klein, Cornel


    In this paper we investigate optimal control of a group of heat pumps. Each heat pump provides space heating and domestic hot water to a single household. Besides a heat pump, each house has a buffer for domestic hot water and a floor heating system for space heating. The paper describes models and

  15. Ethnocultural Groups--The Making of Canada: Economic Contributions to Canadian Life. Report 2: Seven Successful Small Business Entrepreneurs. (United States)

    Dutt, S.; And Others

    Immigrants and refugees come to Canada for many reasons and are often risk-takers. Some ethnic groups follow identifiable patterns of distinctive economic development, while others meld and blend into Canadian society so that no discernible pattern can be identified. This publication provides an overview of the contributions made by seven…

  16. Social Resources Generated by Group Support Networks May Not Be Beneficial to Asian Immigrant-Owned Small Businesses. (United States)

    Bates, Timothy


    Data from the Census Bureau's Characteristics of Business Owners, 1979-87, suggest that the success and survival patterns of businesses owned by Asian immigrants derive from large investments of financial capital and the business owners' superior educational credentials. Questions the validity of attributing this group's self-employment success to…

  17. Safeguarding Digital Library Contents: Charging for Online Content. (United States)

    Herzberg, Amir


    Investigates the need for mechanisms for charging by digital libraries and other providers of online content, in particular for micropayments, i.e., charging for small amounts. The SSL (Secure Socket Layer) and SET (Secure Electronic Transactions) protocols for charge card payments and the MiniPay micropayment mechanism for charging small amounts…

  18. [Benefits of cisplatin-based polychemotherapy in non-small cell bronchogenic carcinoma. Kyushu Lung Cancer Chemotherapy Study Group]. (United States)

    Ohta, M; Hara, N; Ichikawa, Y; Kanda, T; Shima, K; Tamura, K; Hokama, M


    We studied the efficacy of cisplatin-based polychemotherapy for non-small-cell lung cancer. One hundred nineteen patients with adenocarcinoma or large cell carcinoma were randomized to receive cyclophosphamide, adriamycin, cisplatin and mitomycin C (CAPM) or mitomycin C, cytosine arabinoside and tegafur (MCT), and 48 patients with squamous cell carcinoma were randomized to receive cisplatin, adriamycin and peplomycin (PAP) or mitomycin C, cyclophosphamide, tespamine, toyomycin and tegafur (MCTTT). Radiation was given to the chest in patients with stage I-III disease. The response rates were CAPM, 34.5%; MCT, 13.1% (p less than 0.01) and PAP, 63.3%; MCTTT, 42.3%. A significant difference in response rate between the CAPM and MCT regimens was observed only in stage IV patients and not in stage I-III patients. The median survival was 9.5 months in the CAPM arm vs. 6.5 months in the MCT arm (p less than 0.007), and 8.5 months in the PAP arm vs. 6.5 months in the MCTTT arm. Improved median survival for the CAPM regimen was noted only in stage IV patients and not in stage I-III patients when compared to patients given the MCT regimen, respectively. Nausea and vomiting were significantly increased in patients with cisplatin-based polychemotherapy. Myelosuppression was more severe with the CAPM regimen than with the other chemotherapy regimens. We concluded that cisplatin-based polychemotherapy, CAPM and PAP therapy were of more benefit to patients with disseminated non-small-cell lung cancer than MCT and MCTTT therapy.

  19. Benefits of foraging in small groups: An experimental study on public information use in red knots Calidris canutus. (United States)

    Bijleveld, Allert I; van Gils, Jan A; Jouta, Jeltje; Piersma, Theunis


    Social foraging is common and may provide benefits of safety and public information. Public information permits faster and more accurate estimates of patch resource densities, thus allowing more effective foraging. In this paper we report on two experiments with red knots Calidris canutus, socially foraging shorebirds that eat bivalves on intertidal mudflats. The first experiment was designed to show that red knots are capable of using public information, and whether dominance status or sex affected its use. We showed that knots can detect the foraging success of conspecifics and choose a patch accordingly. Neither dominance status nor sex influenced public information use. In the second experiment, by manipulating group size, we investigated whether public information use affected food-patch discovery rates and patch residence times. We showed that the time needed before locating a food patch decreased in proportion to group size. Also, an individual's number of patch visits before locating the food declined with group size, and, to our surprise, their average patch residence time did as well. Moreover, knots differed in their search strategy in that some birds consistently exploited the searching efforts of others. We conclude that socially foraging knots have the potential to greatly increase their food-finding rate by using public information. This article is part of a Special Issue entitled: In Honor of Jerry Hogan. Copyright © 2014 Elsevier B.V. All rights reserved.

  20. N-terminal diproline and charge group effects on the stabilization of helical conformation in alanine-based short peptides: CD studies with water and methanol as solvent. (United States)

    Goyal, Bhupesh; Srivastava, Kinshuk Raj; Durani, Susheel


    Protein folding problem remains a formidable challenge as main chain, side chain and solvent interactions remain entangled and have been difficult to resolve. Alanine-based short peptides are promising models to dissect protein folding initiation and propagation structurally as well as energetically. The effect of N-terminal diproline and charged side chains is assessed on the stabilization of helical conformation in alanine-based short peptides using circular dichroism (CD) with water and methanol as solvent. A1 (Ac-Pro-Pro-Ala-Lys-Ala-Lys-Ala-Lys-Ala-NH 2 ) is designed to assess the effect of N-terminal homochiral diproline and lysine side chains to induce helical conformation. A2 (Ac-Pro-Pro-Glu-Glu-Ala-Ala-Lys-Lys-Ala-NH 2 ) and A3 (Ac-dPro-Pro-Glu-Glu-Ala-Ala-Lys-Lys-Ala-NH 2 ) with N-terminal homochiral and heterochiral diproline, respectively, are designed to assess the effect of Glu...Lys (i, i + 4) salt bridge interactions on the stabilization of helical conformation. The CD spectra of A1, A2 and A3 in water manifest different amplitudes of the observed polyproline II (PPII) signals, which indicate different conformational distributions of the polypeptide structure. The strong effect of solvent substitution from water to methanol is observed for the peptides, and CD spectra in methanol evidence A2 and A3 as helical folds. Temperature-dependent CD spectra of A1 and A2 in water depict an isodichroic point reflecting coexistence of two conformations, PPII and β-strand conformation, which is consistent with the previous studies. The results illuminate the effect of N-terminal diproline and charged side chains in dictating the preferences for extended-β, semi-extended PPII and helical conformation in alanine-based short peptides. The results of the present study will enhance our understanding on stabilization of helical conformation in short peptides and hence aid in the design of novel peptides with helical structures. Copyright © 2017 European Peptide

  1. Recurrent stroke after transient ischaemic attack or minor ischaemic stroke: does the distinction between small and large vessel disease remain true to type? Dutch TIA Trial Study Group.


    Kappelle, L J; van Latum, J C; van Swieten, J C; Algra, A; Koudstaal, P J; van Gijn, J


    The incidence and vascular type of recurrent ischaemic stroke was studied in patients with supratentorial transient ischaemic attacks or non-disabling ischaemic strokes, who were treated with aspirin (30 or 283 mg). Patients were divided into groups with small vessel disease (SVD) (n = 1216) or large vessel disease (LVD) (n = 1221) on the grounds of their clinical features and CT at baseline. Patients with evidence of both SVD and LVD (n = 180) were excluded from further analyses. During foll...

  2. Transition to farming more likely for small, conservative groups with property rights, but increased productivity is not essential. (United States)

    Gallagher, Elizabeth M; Shennan, Stephen J; Thomas, Mark G


    Theories for the origins of agriculture are still debated, with a range of different explanations offered. Computational models can be used to test these theories and explore new hypotheses; Bowles and Choi [Bowles S, Choi J-K (2013) Proc Natl Acad Sci USA 110(22):8830-8835] have developed one such model. Their model shows the coevolution of farming and farming-friendly property rights, and by including climate variability, replicates the timings for the emergence of these events seen in the archaeological record. Because the processes modeled occurred a long time ago, it can be difficult to justify exact parameter values; hence, we propose a fitting to idealized outcomes (FIO) method to explore the model's parameter space in more detail. We have replicated the model of Bowles and Choi, and used the FIO method to identify complexities and interactions of the model previously unidentified. Our results indicate that the key parameters for the emergence of farming are group structuring, group size, conservatism, and farming-friendly property rights (lending further support to Bowles and Choi's original proposal). We also find that although advantageous, it is not essential that farming productivity be greater than foraging productivity for farming to emerge. In addition, we highlight how model behaviors can be missed when gauging parameter sensitivity via a fix-all-but-one variation approach.

  3. Understanding the site selectivity in small-sized neutral and charged Al(n) (4 ≤ N ≤ 7) clusters using density functional theory based reactivity descriptors: a validation study on water molecule adsorption. (United States)

    Das, Susanta; Pal, Sourav; Krishnamurty, Sailaja


    Aluminum clusters are now technologically important due to their high catalytic activity. Our present study on the small-sized aluminum clusters applies density functional theory (DFT)-based reactivity descriptors to identify potential sites for adsorption and eventual chemical reaction. Depending on symmetry, susceptibility of various type of reactive sites within a cluster toward an impending electrophilic and/or nucleophilic attack is predicted using the reactivity descriptors. In addition, the study devises general rules as to how the size, shape, and charge of the cluster influences the number of available sites for an electrophilic and/or nucleophilic attack. The predictions by reactivity descriptors are validated by performing an explicit adsorption of water molecule on Al clusters with four atoms. The adsorption studies demonstrate that the most stable water-cluster complex is obtained when the molecule is adsorbed through an oxygen atom on the site with the highest relative electrophilicity.

  4. Lifting the mask: identification of new small molecule inhibitors of uropathogenic Escherichia coli group 2 capsule biogenesis. (United States)

    Goller, Carlos C; Arshad, Mehreen; Noah, James W; Ananthan, Subramaniam; Evans, Carrie W; Nebane, N Miranda; Rasmussen, Lynn; Sosa, Melinda; Tower, Nichole A; White, E Lucile; Neuenswander, Benjamin; Porubsky, Patrick; Maki, Brooks E; Rogers, Steven A; Schoenen, Frank; Seed, Patrick C


    Uropathogenic Escherichia coli (UPEC) is the leading cause of community-acquired urinary tract infections (UTIs), with over 100 million UTIs occurring annually throughout the world. Increasing antimicrobial resistance among UPEC limits ambulatory care options, delays effective treatment, and may increase overall morbidity and mortality from complications such as urosepsis. The polysaccharide capsules of UPEC are an attractive target a therapeutic, based on their importance in defense against the host immune responses; however, the large number of antigenic types has limited their incorporation into vaccine development. The objective of this study was to identify small-molecule inhibitors of UPEC capsule biogenesis. A large-scale screening effort entailing 338,740 compounds was conducted in a cell-based, phenotypic screen for inhibition of capsule biogenesis in UPEC. The primary and concentration-response assays yielded 29 putative inhibitors of capsule biogenesis, of which 6 were selected for further studies. Secondary confirmatory assays identified two highly active agents, named DU003 and DU011, with 50% inhibitory concentrations of 1.0 µM and 0.69 µM, respectively. Confirmatory assays for capsular antigen and biochemical measurement of capsular sugars verified the inhibitory action of both compounds and demonstrated minimal toxicity and off-target effects. Serum sensitivity assays demonstrated that both compounds produced significant bacterial death upon exposure to active human serum. DU011 administration in mice provided near complete protection against a lethal systemic infection with the prototypic UPEC K1 isolate UTI89. This work has provided a conceptually new class of molecules to combat UPEC infection, and future studies will establish the molecular basis for their action along with efficacy in UTI and other UPEC infections.

  5. Physical Function After Total Knee Replacement: An Observational Study Describing Outcomes in a Small Group of Women From China and the United States. (United States)

    White, Daniel K; Li, Zhichang; Zhang, Yuqing; Marmon, Adam R; Master, Hiral; Zeni, Joseph; Niu, Jingbo; Jiang, Long; Zhang, Shu; Lin, Jianhao


    To describe physical function before and six months after Total Knee Replacement (TKR) in a small sample of women from China and the United States. Observational. Community environment. Both groups adhered to the Osteoarthritis Research Society International (OARSI) protocols for the 6-minute walk and 30-second chair stand. We compared physical function prior to TKR and 6 months after using linear regression adjusted for covariates. Women (N=60) after TKR. Not applicable. Age and body mass index in the China group (n=30; 66y and 27.0kg/m 2 ) were similar to those in the U.S. group (n=30; 65y and 29.6kg/m 2 ). Before surgery, the China group walked 263 (95% confidence interval [CI], -309 to -219) less meters and had 10.2 (95% CI, -11.8 to -8.5) fewer chair stands than the U.S. group. At 6 months when compared with the U.S. group, the China group walked 38 more meters, but this difference did not reach statistical significance (95% CI, -1.6 to 77.4), and had 3.1 (95% CI, -4.4 to -1.7) fewer chair stands. The China group had greater improvement in the 6-minute walk test than did the U.S. group (PChina group had greater gains in walking endurance and similar gains in repeated chair stands than did the U.S. group after surgery. Copyright © 2017 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  6. Novel Emergency Medicine Curriculum Utilizing Self-Directed Learning and the Flipped Classroom Method: Obstetric and Gynecologic Emergencies Small Group Module

    Directory of Open Access Journals (Sweden)

    Jillian McGrath


    Full Text Available Audience: This curriculum, created and implemented at The Ohio State University Wexner Medical Center, was primarily designed to educate our emergency medicine (EM residents (PGY1-3 and emergency medicine/internal medicine (EM/IM residents (PGY1-5 on core obstetrics and gynecology topics in EM. Additional audience members include medical students and faculty physicians. Introduction: In 2013, there were over 1 million emergency department visits in the United States which resulted in primary obstetric or gynecologic diagnoses.1 EM Residents must be proficient in the differential diagnosis and management of the wide variety of obstetric and gynecologic emergencies. To do this, we developed a flipped classroom curricular model, which consists of self-directed learning activities completed by learners, followed by small group discussions pertaining to the topic reviewed. The active learning fostered by this type of curriculum increases faculty and learner engagement and interaction time typically absent in traditional lecture-based formats.2-4 Studies have revealed that the application of knowledge through case studies, personal interaction with content experts, and integrated questions are effective learning strategies for EM residents.4-6 The Ohio State University Wexner Medical Center EM residency didactic curriculum recently transitioned to a “flipped classroom” approach.7-10 Our didactic curriculum is delivered over the course of 18 months; however, it could easily be adapted to other academic calendar cycles. The flipped classroom curriculum maximizes didactic time and resident engagement, fosters intellectual curiosity and active learning, and meets the needs of today’s learners. 3,6,11 Objectives: We aim to teach the presentation and management of obstetric and gynecologic emergencies through the creation of a flipped classroom design. This unique, innovative curriculum utilizes resources chosen by education faculty and resident

  7. Small-group, computer-mediated argumentation in middle-school classrooms: the effects of gender and different types of online teacher guidance. (United States)

    Asterhan, Christa S C; Schwarz, Baruch B; Gil, Julia


    Research has shown the importance of careful teacher support during collaborative group work to promote productive discourse between students (Webb, 2009). However, this research has traditionally focused on face-to-face communication. The role of online teacher guidance of small-group computer-mediated discussions has received little attention, especially in secondary school classroom settings. Researchers of computer-supported collaborative learning (CSCL), on the other hand, have traditionally focused on software-embedded features, such as scripts, to support a-synchronous peer dialogue, and less so on human guidance of synchronous group discussions. The main aim of the present in vivo, experimental study is to examine whether online teacher guidance can improve the quality of small-group synchronous discussions, and whether different types of guidance (epistemic or interaction guidance) affect these discussions differently, when compared to an unguided condition. The second goal of this study is to explore potential differences between all-female and all-male discussion groups. Eighty-two 9th graders (three classrooms) and six teachers from a rural high school in Israel. Whereas epistemic guidance only improved aspects of the argumentative quality of the discussion, interaction guidance only improved aspects of collaboration. Discussions of all-girls groups scored higher on aspects of collaboration and argumentative quality, compared to all-boys groups. The findings show that teacher guidance of synchronous, online discussions in classrooms is realizable and reasonably reaches its intended goals. Training should be focused on acquiring various guidance strategies to augment their beneficial effects. Furthermore, future research should pay more attention to potential gender differences in peer-to-peer argumentation. ©2011 The British Psychological Society.

  8. Thermal properties of some small peptides (N-acetyl-amino acid-N′-methylamides) with non-polar side groups

    International Nuclear Information System (INIS)

    Badea, Elena; Della Gatta, Giuseppe; Pałecz, Bartłomiej


    Highlights: • T fus and Δ fus H m of methylamides of N-acetyl substituted non-polar amino acids were measured. • T fus and Δ fus H m increased as a function of the molar mass of the alkyl side chains. • DL racemates showed T fus of about 40 °C lower than those of the corresponding pure L enantiomers. • Ideal solubility of solids at T = 298.15 K was estimated based on their T fus and Δ fus S m . - Abstract: Temperatures and molar enthalpies of fusion of a series of uncharged small peptides, namely the methylamides of N-acetyl substituted glycine, α-amino-butyric acid, alanine, valine, norvaline, leucine, isoleucine, norleucine, and proline, were measured by differential scanning calorimetry (d.s.c.), and molar entropies of fusion were derived. Both L- and DL-compunds were taken into account for the chiral molecules. No solid-to-solid transitions were detected from room temperature to fusion except for N-acetyl-N′-methyl alaninamide. Comparisons were made with the values for the N-acetyl amides of the corresponding amino acids previously reported. Both L enantiomers and DL racemates of α-aminobutyric acid, alanine, valine and isoleucine methylamides displayed temperatures of fusion sharply increasing as a function of molar mass, whereas much lower values, in countertendency with their molar mass increase, were found for proline and leucine methylamides. The racemic DL crystals showed temperatures of fusion of about 40 °C lower than those of the corresponding pure L enantiomers, except for proline and leucine derivatives. The enthalpies and entropies of fusion also varied as a function of molar mass following a similar trend with that of temperatures of fusion, except for alanine derivatives which showed lower values than expected. The values of ideal solubility of solids at T = 298.15 K were estimated based on their temperatures and molar entropies of fusion. Results were discussed with reference to the packing patterns based on hydrogen bonding and

  9. Molecular dynamics simulations to examine structure, energetics, and evaporation/condensation dynamics in small charged clusters of water or methanol containing a single monatomic ion. (United States)

    Daub, Christopher D; Cann, Natalie M


    We study small clusters of water or methanol containing a single Ca(2+), Na(+), or Cl(-) ion with classical molecular dynamics simulations, using models that incorporate polarizability via the Drude oscillator framework. Evaporation and condensation of solvent from these clusters is examined in two systems, (1) for isolated clusters initially prepared at different temperatures and (2) those with a surrounding inert (Ar) gas of varying temperature. We examine these clusters over a range of sizes, from almost bare ions up to 40 solvent molecules. We report data on the evaporation and condensation of solvent from the clusters and argue that the observed temperature dependence of evaporation in the smallest clusters demonstrates that the presence of heated gas alone cannot, in most cases, solely account for bare ion production in electrospray ionization (ESI), neglecting the key contribution of the electric field. We also present our findings on the structure and energetics of the clusters as a function of size. Our data agree well with the abundant literature on hydrated ion clusters and offer some novel insight into the structure of methanol and ion clusters, especially those with a Cl(-) anion, where we observe the presence of chain-like structures of methanol molecules. Finally, we provide some data on the reparameterizations necessary to simulate ions in methanol using the separately developed Drude oscillator models for methanol and for ions in water.

  10. Spotted Fever Group Rickettsia in Small Rodents from Areas of Low Endemicity for Brazilian Spotted Fever in the Eastern Region of Minas Gerais State, Brazil (United States)

    Milagres, Bruno S.; Padilha, Amanda F.; Montandon, Carlos E.; Freitas, Renata N.; Pacheco, Richard; Walker, David H.; Labruna, Marcelo B.; Mafra, Cláudio L.; Galvão, Márcio A. M.


    We investigated the humoral immune response against different species of Rickettsia in serum samples from small rodents collected in two areas of a silent focus for Brazilian spotted fever in the eastern region of Minas Gerais State, Brazil. Sera samples were analyzed by indirect immunofluorescence assay using antigens from Rickettsia species of the spotted fever, ancestral, and transition groups. Titers ≥ 1:64 were considered positive. In Santa Cruz do Escalvado, 94% (30 of 32) of the samples collected from Rattus rattus, 22% (5 of 23) from Nectomys squamipes, and 80% (4 of 5) from Akodon sp., reacted by indirect immunofluorescence assay with Rickettsia antigens of the spotted fever group. In the municipality of Pingo D'Água, 84% (26 of 31) of the samples collected from R. rattus, 86% (6 of 7) of the samples from Oryzomys subflavus, 86% (6 of 7) from N. squamipes, and 100% (1 of 1) from Bolomys sp. contained antibodies that reacted with rickettsial antigens of the spotted fever group. These results demonstrated the previous exposure of small rodents to spotted fever group Rickettsia, suggesting the participation of these animals in the natural history of these rickettsiae in this region. PMID:23509125

  11. Enhancement in evaluating small group work in courses with large number of students. Machine theory at industrial engineering degrees

    Directory of Open Access Journals (Sweden)

    Lluïsa Jordi Nebot


    Full Text Available This article examines new tutoring evaluation methods to be adopted in the course, Machine Theory, in the Escola Tècnica Superior d’Enginyeria Industrial de Barcelona (ETSEIB, Universitat Politècnica de Catalunya. These new methods have been developed in order to facilitate teaching staff work and include students in the evaluation process. Machine Theory is a required course with a large number of students. These students are divided into groups of three, and required to carry out a supervised work constituting 20% of their final mark. These new evaluation methods were proposed in response to the significant increase of students in spring semester of 2010-2011, and were pilot tested during fall semester of academic year 2011-2012, in the previous Industrial Engineering degree program. Pilot test results were highly satisfactory for students and teachers, alike, and met proposed educational objectives. For this reason, the new evaluation methodology was adopted in spring semester of 2011-2012, in the current bachelor’s degree program in Industrial Technology (Grau en Enginyeria en Tecnologies Industrials, GETI, where it has also achieved highly satisfactory results.

  12. Separation of charge movement components in mammalian skeletal muscle fibres. (United States)

    Francini, F; Bencini, C; Piperio, C; Squecco, R


    1. Intramembrane charge movements, I(ICM), were measured in rat skeletal muscle fibres in response to voltage steps from a -90 mV holding potential to a wide test voltage range (-85 to 30 mV), using a double Vaseline-gap voltage-clamp technique. Solutions were designed to minimise ionic currents. Ca(2+) current was blocked by adding Cd(2+) (0.8 mM) to the external solution. In a subset of experiments Cd(2+) was omitted to determine which components of the charge movement best correlated with L-type Ca(2+) channel gating. 2. Detailed kinetic analysis of I(ICM) identified two major groups of charges. The first two components, designated Q(a) and Q(b), were the only charges moved by small depolarising steps. The second group of components, Q(c) and Q(d), showed a more positive voltage threshold, -35.6 +/- 2.0 mV, (n = 6) in external solution with Cd(2+), and -41.1 +/- 2.0 mV (n = 12) in external solution without Cd(2+). Notably, in external solution without Cd(2+) the voltage threshold of Ca(2+) current, I(Ca), activation had a similar value, being -38.1 +/- 2.4 mV. 3. The sum of three Boltzmann functions, Q(1), Q(2) and Q(3), showing progressively more positive transition voltages, could be fitted to charge versus voltage, Q(ICM)-V, plots. The three Boltzmann terms identified three charge components: Q(1) described the shallow voltage-dependent Q(a) and Q(b) charges, Q(2) and Q(3) described the steep voltage-dependent Q(c) and Q(d) charges. 4. In external solution without Cd(2+) the charge kinetics changed: a slow decaying phase was replaced by a pronounced delayed hump. Moreover, the transition voltages of the individual steady-state charge components were shifted towards negative potentials (from 6.3 to 8.2 mV). Nevertheless, the overall charge and steepness factors were conserved. 5. In conclusion, these experiments allowed a clear separation of four components of intramembrane charge movements in rat skeletal muscle, showing that there are no fundamental

  13. Effects of coaching on educators' and preschoolers' use of references to print and phonological awareness during a small-group craft/writing activity. (United States)

    Milburn, Trelani F; Hipfner-Boucher, Kathleen; Weitzman, Elaine; Greenberg, Janice; Pelletier, Janette; Girolametto, Luigi


    The current study investigated the effects of coaching as part of an emergent literacy professional development program to increase early childhood educators' use of verbal references to print and phonological awareness during interactions with children. Thirty-one educators and 4 children from each of their classrooms (N = 121) were randomly assigned to an experimental group (21 hr of in-service workshops plus 5 coaching sessions) and a comparison group (workshops alone). The in-service workshops included instruction on how to talk about print and phonological awareness during a post-story craft/writing activity. All educators were video-recorded during a 15-min craft/writing activity with a small group of preschoolers at pretest and posttest. All videotapes were transcribed and coded for verbal references to print and phonological awareness by the educators and children. Although at posttest, there were no significant group differences in the educators' or the children's references to print as measured by rate per minute, both the educators and the children in the experimental group used a significantly higher rate per minute of references to phonological awareness relative to the comparison group. Professional development that included coaching with a speech-language pathologist enabled educators and children to engage in more phonological awareness talk during this activity.

  14. Charge Transport Processes in Molecular Junctions (United States)

    Smith, Christopher Eugene

    Molecular electronics (ME) has evolved into a rich area of exploration that combines the fields of chemistry, materials, electronic engineering and computational modeling to explore the physics behind electronic conduction at the molecular level. Through studying charge transport properties of single molecules and nanoscale molecular materials the field has gained the potential to bring about new avenues for the miniaturization of electrical components where quantum phenomena are utilized to achieve solid state molecular device functionality. Molecular junctions are platforms that enable these studies and consist of a single molecule or a small group of molecules directly connected to electrodes. The work presented in this thesis has built upon the current understanding of the mechanisms of charge transport in ordered junctions using self-assembled monolayer (SAM) molecular thin films. Donor and acceptor compounds were synthesized and incorporated into SAMs grown on metal substrates then the transport properties were measured with conducting probe atomic force microscopy (CP-AFM). In addition to experimentally measured current-voltage (I-V) curves, the transport properties were addressed computationally and modeled theoretically. The key objectives of this project were to 1) investigate the impact of molecular structure on hole and electron charge transport, 2) understand the nature of the charge carriers and their structure-transport properties through long (films, and open opportunities to engineer improved electronic functionality into molecular devices.

  15. Charge migration and charge transfer in molecular systems

    Directory of Open Access Journals (Sweden)

    Hans Jakob Wörner


    Full Text Available The transfer of charge at the molecular level plays a fundamental role in many areas of chemistry, physics, biology and materials science. Today, more than 60 years after the seminal work of R. A. Marcus, charge transfer is still a very active field of research. An important recent impetus comes from the ability to resolve ever faster temporal events, down to the attosecond time scale. Such a high temporal resolution now offers the possibility to unravel the most elementary quantum dynamics of both electrons and nuclei that participate in the complex process of charge transfer. This review covers recent research that addresses the following questions. Can we reconstruct the migration of charge across a molecule on the atomic length and electronic time scales? Can we use strong laser fields to control charge migration? Can we temporally resolve and understand intramolecular charge transfer in dissociative ionization of small molecules, in transition-metal complexes and in conjugated polymers? Can we tailor molecular systems towards specific charge-transfer processes? What are the time scales of the elementary steps of charge transfer in liquids and nanoparticles? Important new insights into each of these topics, obtained from state-of-the-art ultrafast spectroscopy and/or theoretical methods, are summarized in this review.

  16. Charge-pump voltage converter (United States)

    Brainard, John P [Albuquerque, NM; Christenson, Todd R [Albuquerque, NM


    A charge-pump voltage converter for converting a low voltage provided by a low-voltage source to a higher voltage. Charge is inductively generated on a transfer rotor electrode during its transit past an inductor stator electrode and subsequently transferred by the rotating rotor to a collector stator electrode for storage or use. Repetition of the charge transfer process leads to a build-up of voltage on a charge-receiving device. Connection of multiple charge-pump voltage converters in series can generate higher voltages, and connection of multiple charge-pump voltage converters in parallel can generate higher currents. Microelectromechanical (MEMS) embodiments of this invention provide a small and compact high-voltage (several hundred V) voltage source starting with a few-V initial voltage source. The microscale size of many embodiments of this invention make it ideally suited for MEMS- and other micro-applications where integration of the voltage or charge source in a small package is highly desirable.

  17. Use of care management practices in small- and medium-sized physician groups: do public reporting of physician quality and financial incentives matter? (United States)

    Alexander, Jeffrey A; Maeng, Daniel; Casalino, Lawrence P; Rittenhouse, Diane


    To examine the effect of public reporting (PR) and financial incentives tied to quality performance on the use of care management practices (CMPs) among small- and medium-sized physician groups. Survey data from The National Study of Small and Medium-sized Physician Practices were used. Primary data collection was also conducted to assess community-level PR activities. The final sample included 643 practices engaged in quality reporting; about half of these practices were subject to PR. We used a treatment effects model. The instrumental variables were the community-level variables that capture the level of PR activity in each community in which the practices operate. (1) PR is associated with increased use of CMPs, but the estimate is not statistically significant; (2) financial incentives are associated with greater use of CMPs; (3) practices' awareness/sensitivity to quality reports is positively related to their use of CMPs; and (4) combined PR and financial incentives jointly affect CMP use to a greater degree than either of these factors alone. Small- to medium-sized practices appear to respond to PR and financial incentives by greater use of CMPs. Future research needs to investigate the appropriate mix and type of incentive arrangements and quality reporting. © Health Research and Educational Trust.

  18. Small power and heat generation systems on the basis of propulsion and innovative reactor technologies. Proceedings of an advisory group meeting

    International Nuclear Information System (INIS)


    In the future for developing regions and remote areas one or two power reactors in the 50 MWe to 100 MWe range could be appropriately applied for electricity and heat generation. Introducing and managing such a small program with conventional reactor systems would require a mature supporting technological infrastructure and many skilled highly-trained staff at the site, which might be a problem in some countries. An increased number of small conventional reactors would increase the burden and expenditure for assuring security and non-proliferation. To this end, the time has come to develop an innovative small reactor concept which meets the following requirements: reliable, safe operation with a minimum maintenance and supporting infrastructure, economic competitiveness with alternative energy sources available to the candidate sites, and significant improvements in proliferation resistance relative to existing reactor systems. Successful resolution of such a problem requires a comprehensive system approach that considers all aspects of manufacturing, transportation, operation and ultimate disposal. Some elements of this approach have been used previously in the development of propulsion nuclear power systems, with consideration given to many diverse requirements such as highly autonomous operation for a long period of time, no planned maintenance, no on-site refueling and ultimate disposition. It is with this focus that the IAEA convened the Advisory Group on Propulsion Reactor technologies for Civilian Applications

  19. Charge stabilization by reaction center protein immobilized to carbon nanotubes functionalized by amine groups and poly(3-thiophene acetic acid) conducting polymer

    Energy Technology Data Exchange (ETDEWEB)

    Szabo, T.; Magyar, M.; Nagy, L. [Department of Medical Physics and Informatics, University of Szeged, H-6720 Szeged (Hungary); Nemeth, Z.; Hernadi, K. [Department of Applied and Environmental Chemistry, University of Szeged, H-6720 Szeged (Hungary); Endrodi, B.; Bencsik, G.; Visy, Cs. [Department of Physical Chemistry and Materials Science, University of Szeged, H-6720 Szeged (Hungary); Horvath, E.; Magrez, A.; Forro, L. [Institute of Physics of Complex Matter, Ecole Polytechnique Federale de Lausanne, CH-1015 Lausanne (Switzerland)


    A large number of studies have indicated recently that photosynthetic reaction center proteins (RC) bind successfully to nanostructures and their functional activity is largely retained. The major goal of current research is to find the most efficient systems and conditions for the photoelectric energy conversion and for the stability of this bio-nanocomposite. In our studies, we immobilized the RC protein on multiwalled carbon nanotubes (MWNT) through specific chemical binding to amine functional groups and through conducting polymer (poly(3-thiophene acetic acid), PTAA). Both structural (TEM, AFM) and functional (absorption change and conductivity) measurements has shown that RCs could be bound effectively to functionalized CNTs. The kinetics of the light induced absorption change indicated that RCs were still active in the composite and there was an interaction between the protein cofactors and the CNTs. The light generated photocurrent was measured in an electrochemical cell with transparent CNT electrode designed specially for this experiment. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  20. Study of the cost-benefit analysis method for safety. Meeting of the Permanent Group in charge of nuclear reactors on the 5 July 2007

    International Nuclear Information System (INIS)


    After a recall of the history of the issue of third decennial visit of the 900 MW reactors, of the IRSN preliminary analysis, of elements given to the Permanent Group, of requests made by the ASN, and a presentation of the analysis performed by the IRSN, this large report presents the cost-benefit analysis method and its potential applications (principle, cost assessment, safety assessment, examples) and reports international experience gained in this area: the risk-informed approach (within the IAEA, in the USA, France and other European countries, the specific cost-benefit approach), existing cost-benefit type methods (comparison between methods used in the USA, in France and in Canada), and monetary assessment of accidents. It reports the application of the cost-benefit method for safety and its limitations, and then its application to modifications which have been implemented after safety re-examinations. It discusses the use of level 1 and 2 safety probabilistic studies, and reports the use of a cost-benefit method for safety within the frame of safety re-examinations

  1. Beneficial effect of two culture systems with small groups of embryos on the development and quality of in vitro-produced bovine embryos. (United States)

    Cebrian-Serrano, A; Salvador, I; Silvestre, M A


    Currently, in vitro-produced embryos derived by ovum pick up (OPU) and in vitro fertilization (IVF) technologies represent approximately one-third of the embryos worldwide in cattle. Nevertheless, the culture of small groups of embryos from an individual egg donor is an issue that OPU-IVF laboratories have to face. In this work, we tested whether the development and quality of the preimplantation embryos in vitro cultured in low numbers (five embryos) could be improved by the addition of epidermal growth factor, insulin, transferrin and selenium (EGF-ITS) or by the WOW system. With this aim, immature oocytes recovered from slaughtered heifers were in vitro matured and in vitro fertilized. Presumptive zygotes were then randomly cultured in four culture conditions: one large group (LG) (50 embryos/500 μl medium) and three smaller groups [five embryos/50 μl medium without (control) or with EGF-ITS (EGF-ITS) and five embryos per microwell in the WOW system (WOW)]. Embryos cultured in LG showed a greater ability to develop to blastocyst stage than embryos cultured in smaller groups, while the blastocyst rate of WOW group was significantly higher than in control. The number of cells/blastocyst in LG was higher than control or WOW, whereas the apoptosis rate per blastocyst was lower. On the other hand, the addition of EGF-ITS significantly improved both parameters compared to the control and resulted in similar embryo quality to LG. In conclusion, the WOW system improved embryo development, while the addition of EGF-ITS improved the embryo quality when smaller groups of embryos were cultured. © 2013 Blackwell Verlag GmbH.

  2. Hidden charged dark matter

    International Nuclear Information System (INIS)

    Feng, Jonathan L.; Kaplinghat, Manoj; Tu, Huitzu; Yu, Hai-Bo


    Can dark matter be stabilized by charge conservation, just as the electron is in the standard model? We examine the possibility that dark matter is hidden, that is, neutral under all standard model gauge interactions, but charged under an exact (\\rm U)(1) gauge symmetry of the hidden sector. Such candidates are predicted in WIMPless models, supersymmetric models in which hidden dark matter has the desired thermal relic density for a wide range of masses. Hidden charged dark matter has many novel properties not shared by neutral dark matter: (1) bound state formation and Sommerfeld-enhanced annihilation after chemical freeze out may reduce its relic density, (2) similar effects greatly enhance dark matter annihilation in protohalos at redshifts of z ∼ 30, (3) Compton scattering off hidden photons delays kinetic decoupling, suppressing small scale structure, and (4) Rutherford scattering makes such dark matter self-interacting and collisional, potentially impacting properties of the Bullet Cluster and the observed morphology of galactic halos. We analyze all of these effects in a WIMPless model in which the hidden sector is a simplified version of the minimal supersymmetric standard model and the dark matter is a hidden sector stau. We find that charged hidden dark matter is viable and consistent with the correct relic density for reasonable model parameters and dark matter masses in the range 1 GeV ∼ X ∼< 10 TeV. At the same time, in the preferred range of parameters, this model predicts cores in the dark matter halos of small galaxies and other halo properties that may be within the reach of future observations. These models therefore provide a viable and well-motivated framework for collisional dark matter with Sommerfeld enhancement, with novel implications for astrophysics and dark matter searches

  3. Detection of homogeneous distribution of functional groups in mesoporous silica by small angle neutron scattering and in situ adsorption of nitrogen or water. (United States)

    Sharifi, Monir; Marschall, Roland; Wilhelm, Michaela; Wallacher, Dirk; Wark, Michael


    The distribution of SO(3)H-functional groups attached to the ordered inner pore walls of mesoporous Si-MCM-41 materials based on SiO(2) was investigated by gas adsorption combined with in situ small angle neutron scattering (SANS). The functionalization was performed by two different methods, (i) grafting and (ii) co-condensation. The adsorbates N(2) at 77 K or a H(2)O/D(2)O mixture of 42:58 at 298 K possess neutron scattering length densities (SLD) similar to that of SiO(2) and therefore quench the diffraction signals of the nonmodified silica. SANS measurements show that N(2) matches completely not only with the pristine mesoporous Si-MCM-41 but also with Si-MCM-41-SO(3)H functionalized by grafting. Thus, full access of adsorbate into the entire length of the pores is proven. For the analysis of the distribution of functional groups within the pores in dependence on the used functionalization method, grafting or co-condensation, however, the more specific adsorbate H(2)O/D(2)O (42:58) is necessary, because it reacts more sensitively toward small changes in the SLD of the host material. For grafted Si-MCM-41-SO(3)H materials, an incomplete quenching was observed, indicating that only some regions, probably the pore mouths, have been modified. For a sample functionalized by co-condensation, almost no quenching of the neutron diffraction was found, indicating a very homogeneous distribution of the functional groups along the entire pores.

  4. Effects of the charge-transfer reorganization energy on the open-circuit voltage in small-molecular bilayer organic photovoltaic devices: comparison of the influence of deposition rates of the donor. (United States)

    Lee, Chih-Chien; Su, Wei-Cheng; Chang, Wen-Chang


    The theoretical maximum of open-circuit voltage (VOC) of organic photovoltaic (OPV) devices has yet to be determined, and its origin remains debated. Here, we demonstrate that VOC of small-molecule OPV devices can be improved by controlling the deposition rate of a donor without changing the interfacial energy gap at the donor/acceptor interface. The measurement of external quantum efficiency and electroluminescence spectra facilitates the observation of the existence of charge transfer (CT) states. A simplified approach by reusing the reciprocity relationship for obtaining the properties of the CT states is proposed without introducing complex techniques. We compare experimental and fitting results and propose that reorganization energy is the primary factor in determining VOC instead of either the CT energy or electronic coupling term in bilayer OPV devices. Atomic force microscopy images indicate a weak molecular aggregation when a higher deposition rate is used. The results of temperature-dependent measurements suggest the importance of molecular stacking for the CT properties.

  5. Distribution of functional groups in periodic mesoporous organosilica materials studied by small-angle neutron scattering with in situ adsorption of nitrogen

    Directory of Open Access Journals (Sweden)

    Monir Sharifi


    Full Text Available Periodic mesoporous materials of the type (R′O3Si-R-Si(OR′3 with benzene as an organic bridge and a crystal-like periodicity within the pore walls were functionalized with SO3H or SO3− groups and investigated by small-angle neutron scattering (SANS with in situ nitrogen adsorption at 77 K. If N2 is adsorbed in the pores the SANS measurements show a complete matching of all of the diffraction signals that are caused by the long-range ordering of the mesopores in the benzene-PMO, due to the fact that the benzene-PMO walls possess a neutron scattering length density (SLD similar to that of nitrogen in the condensed state. However, signals at higher q-values (>1 1/Å are not affected with respect to their SANS intensity, even after complete pore filling, confirming the assumption of a crystal-like periodicity within the PMO material walls due to π–π interactions between the organic bridges. The SLD of pristine benzene-PMO was altered by functionalizing the surface with different amounts of SO3H-groups, using the grafting method. For a low degree of functionalization (0.81 mmol SO3H·g−1 and/or an inhomogeneous distribution of the SO3H-groups, the SLD changes only negligibly, and thus, complete contrast matching is still found. However, for higher amounts of SO3H-groups (1.65 mmol SO3H·g−1 being present in the mesopores, complete matching of the neutron diffraction signals is no longer observed proving that homogeneously distributed SO3H-groups on the inner pore walls of the benzene-PMO alter the SLD in a way that it no longer fits to the SLD of the condensed N2.

  6. Distribution of functional groups in periodic mesoporous organosilica materials studied by small-angle neutron scattering with in situ adsorption of nitrogen. (United States)

    Sharifi, Monir; Wallacher, Dirk; Wark, Michael


    Periodic mesoporous materials of the type (R'O)(3)Si-R-Si(OR')(3) with benzene as an organic bridge and a crystal-like periodicity within the pore walls were functionalized with SO(3)H or SO(3) (-) groups and investigated by small-angle neutron scattering (SANS) with in situ nitrogen adsorption at 77 K. If N(2) is adsorbed in the pores the SANS measurements show a complete matching of all of the diffraction signals that are caused by the long-range ordering of the mesopores in the benzene-PMO, due to the fact that the benzene-PMO walls possess a neutron scattering length density (SLD) similar to that of nitrogen in the condensed state. However, signals at higher q-values (>1 1/Å) are not affected with respect to their SANS intensity, even after complete pore filling, confirming the assumption of a crystal-like periodicity within the PMO material walls due to π-π interactions between the organic bridges. The SLD of pristine benzene-PMO was altered by functionalizing the surface with different amounts of SO(3)H-groups, using the grafting method. For a low degree of functionalization (0.81 mmol SO(3)H·g(-1)) and/or an inhomogeneous distribution of the SO(3)H-groups, the SLD changes only negligibly, and thus, complete contrast matching is still found. However, for higher amounts of SO(3)H-groups (1.65 mmol SO(3)H·g(-1)) being present in the mesopores, complete matching of the neutron diffraction signals is no longer observed proving that homogeneously distributed SO(3)H-groups on the inner pore walls of the benzene-PMO alter the SLD in a way that it no longer fits to the SLD of the condensed N(2).

  7. Spacelike charges, null-plane charges, and mass splitting

    International Nuclear Information System (INIS)

    Gal-Ezer, E.; Horwitz, L.P.


    The properties of charges defined as integrals over tensor densities and their possible use in the treatment of broken symmetries are studied. It is well known that spacelike integrals over nonconserved densities cannot yield charge operators at a fixed sharp time. However, charge operators which are smeared in time with suitable ''adiabatic'' functions, when there is a mass gap, are well defined; these charges can give rise to a finite algebraic structure only in the infinite-momentum limit, corresponding to an algebra of null-plane charges. For the study of null-plane charges, tensor densities are divided into four classes (very good, good, bad, very bad) according to their transformation properties under the Lorentz group. We argue that in the absence of massless particles members of the first two classes are expected to yield well-defined null-plane charges, while members of the last two classes are not expected to define null-plane charges. The existence of null-plane charges for good densities depends on whether the Pomeron intercept α/sub P/(0) is less than 1 or equal to 1. Null-plane Fourier transforms (which appear in the discussion of current algebra at infinite momentum) are also considered. Null-plane charges may satisfy algebraic relations which involve the Poincare algebra. Owing to domain properties, only semialgebraic relations, which are a generalization of the usual Lie algebraic relations, can be postulated on particle states. By use of these relations, a no-go theorem of the O'Raifeartaigh type, which applies to the null-plane charges, is formulated and proved

  8. Fractionally charged particles and one Dirac charge magnetic monopoles: Are they compatible?

    Directory of Open Access Journals (Sweden)

    V.A. Rubakov


    Full Text Available The simultaneous existence of fractional electric charges and one Dirac charge magnetic monopoles implies the existence of a long-ranged force different from electromagnetism. This may be either unconfined colour or/and some new gauge interaction. In the latter case, ordinary matter could (and, if colour is unbroken, should carry new charge. This charge, however small the coupling constant be, could be experimentally observed in interactions of monopoles with matter. An experiment for checking this possibility is suggested.

  9. Context matters: volunteer bias, small sample size, and the value of comparison groups in the assessment of research-based undergraduate introductory biology lab courses. (United States)

    Brownell, Sara E; Kloser, Matthew J; Fukami, Tadashi; Shavelson, Richard J


    The shift from cookbook to authentic research-based lab courses in undergraduate biology necessitates the need for evaluation and assessment of these novel courses. Although the biology education community has made progress in this area, it is important that we interpret the effectiveness of these courses with caution and remain mindful of inherent limitations to our study designs that may impact internal and external validity. The specific context of a research study can have a dramatic impact on the conclusions. We present a case study of our own three-year investigation of the impact of a research-based introductory lab course, highlighting how volunteer students, a lack of a comparison group, and small sample sizes can be limitations of a study design that can affect the interpretation of the effectiveness of a course.

  10. Pilot investigation of the circadian plasma melatonin rhythm across the menstrual cycle in a small group of women with premenstrual dysphoric disorder.

    Directory of Open Access Journals (Sweden)

    Ari Shechter

    Full Text Available Women with premenstrual dysphoric disorder (PMDD experience mood deterioration and altered circadian rhythms during the luteal phase (LP of their menstrual cycles. Disturbed circadian rhythms may be involved in the development of clinical mood states, though this relationship is not fully characterized in PMDD. We therefore conducted an extensive chronobiological characterization of the melatonin rhythm in a small group of PMDD women and female controls. In this pilot study, participants included five women with PMDD and five age-matched controls with no evidence of menstrual-related mood disorders. Participants underwent two 24-hour laboratory visits, during the follicular phase (FP and LP of the menstrual cycle, consisting of intensive physiological monitoring under "unmasked", time-isolation conditions. Measures included visual analogue scale for mood, ovarian hormones, and 24-hour plasma melatonin. Mood significantly (P≤.03 worsened during LP in PMDD compared to FP and controls. Progesterone was significantly (P = .025 increased during LP compared to FP, with no between-group differences. Compared to controls, PMDD women had significantly (P<.05 decreased melatonin at circadian phases spanning the biological night during both menstrual phases and reduced amplitude of its circadian rhythm during LP. PMDD women also had reduced area under the curve of melatonin during LP compared to FP. PMDD women showed affected circadian melatonin rhythms, with reduced nocturnal secretion and amplitude during the symptomatic phase compared to controls. Despite our small sample size, these pilot findings support a role for disturbed circadian rhythms in affective disorders. Possible associations with disrupted serotonergic transmission are proposed.

  11. Results of the American College of Surgeons Oncology Group Z0050 trial: the utility of positron emission tomography in staging potentially operable non-small cell lung cancer. (United States)

    Reed, Carolyn E; Harpole, David H; Posther, Katherine E; Woolson, Sandra L; Downey, Robert J; Meyers, Bryan F; Heelan, Robert T; MacApinlac, Homer A; Jung, Sin-Ho; Silvestri, Gerard A; Siegel, Barry A; Rusch, Valerie W


    The American College of Surgeons Oncology Group undertook a trial to ascertain whether positron emission tomography with 18F-fluorodeoxyglucose could detect lesions that would preclude pulmonary resection in a group of patients with documented or suspected non-small cell lung cancer found to be surgical candidates by routine staging procedures. A total of 303 eligible patients registered from 22 institutions underwent positron emission tomography after routine staging (computed tomography of chest and upper abdomen, bone scintigraphy, and brain imaging) had deemed their tumors resectable. Positive findings required confirmatory procedures. Positron emission tomography was significantly better than computed tomography for the detection of N1 and N2/N3 disease (42% vs 13%, P =.0177, and 58% vs 32%, P =.0041, respectively). The negative predictive value of positron emission tomography for mediastinal node disease was 87%. Unsuspected metastatic disease or second primary malignancy was identified in 18 of 287 patients (6.3%). Distant metastatic disease indicated in 19 of 287 patients (6.6%) was subsequently shown to be benign. By correctly identifying advanced disease (stages IIIA, IIIB, and IV) or benign lesions, positron emission tomography potentially avoided unnecessary thoracotomy in 1 of 5 patients. In patients with suspected or proven non-small cell lung cancer considered resectable by standard staging procedures, positron emission tomography can prevent nontherapeutic thoracotomy in a significant number of cases. Use of positron emission tomography for mediastinal staging should not be relied on as a sole staging modality, and positive findings should be confirmed by mediastinoscopy. Metastatic disease, especially a single site, identified by positron emission tomography requires further confirmatory evaluation.

  12. Reducing HIV risk among Hispanic/Latino men who have sex with men: Qualitative analysis of behavior change intentions by participants in a small-group intervention (United States)

    Alonzo, Jorge; Mann, Lilli; Tanner, Amanda E.; Sun, Christina J.; Painter, Thomas M.; Freeman, Arin; Reboussin, Beth A.; Song, Eunyoung; Rhodes, Scott D.


    Objective The southeastern United States has the fastest-growing Hispanic/Latino population in the country and carries a disproportionate HIV burden. Among Hispanics/Latinos, men, and men who have sex with men (MSM) in particular, are at elevated risk of HIV infection; however, very few efficacious behavioral HIV prevention interventions are available for use with this vulnerable population. To address this shortage of prevention resources, our community-based participatory research (CBPR) partnership developed and is currently evaluating the efficacy of the HOLA en Grupos intervention to increase condom use and HIV testing among Hispanic/Latino MSM. Methods We recruited 304 Hispanic/Latino MSM who were randomized to receive the small group HOLA en Grupos intervention that was implemented during four 4-hour long sessions over four consecutive Sundays, or a 4-session small group general health education comparison intervention. At the end of the fourth session of the HOLA en Grupos intervention, the intervention facilitators asked participants to write down the sexual health-related behaviors they intended to change as a result of their participation. Results Qualitative analysis of the participants’ responses identified six types of intended behavior changes: increasing and maintaining condom use; identifying strategies to support correct and consistent condom use; increasing communication and negotiation with sexual partners about condom use; getting tested for HIV and other sexually transmitted infections; applying other sexual health promotion strategies; and sharing newly learned sexual health information with their peers. Conclusion Most risk-reduction intentions aligned with the intervention’s key messages of using condoms consistently and getting tested for HIV. However, participants’ stated intentions may have also depended on which behavior changes they perceived as most salient after participating in the intervention. Participants’ intentions to

  13. Generation of fast multiply charged ions in conical targets

    International Nuclear Information System (INIS)

    Demchenko, V.V.; Chukbar, K.V.


    So-called conical targets, when the thermonuclear fuel is compressed and heated in a conical cavity in a heavy material (lead, gold, etc.) with the help of a spherical segment that is accelerated by a laser pulse or a beam of charged particles, are often employed in experimental studies of inertial-confinement fusion. In spite of the obvious advantages of such a scheme, one of which is a significant reduction of the required energy input compared with the complete spherical target, it also introduces additional effects into the process of cumulation of energy. In this paper the authors call attention to an effect observed in numerical calculations: the hydrodynamic heating of a small group of multiply charged heavy ions of the walls of the conical cavity up to high energies (T i approx-gt 100 keV). This effect ultimately occurs as a result of the high radiation losses of a multiply charged plasma

  14. Big break for charge symmetry

    CERN Document Server

    Miller, G A


    Two new experiments have detected charge-symmetry breaking, the mechanism responsible for protons and neutrons having different masses. Symmetry is a crucial concept in the theories that describe the subatomic world because it has an intimate connection with the laws of conservation. The theory of the strong interaction between quarks - quantum chromodynamics - is approximately invariant under what is called charge symmetry. In other words, if we swap an up quark for a down quark, then the strong interaction will look almost the same. This symmetry is related to the concept of sup i sospin sup , and is not the same as charge conjugation (in which a particle is replaced by its antiparticle). Charge symmetry is broken by the competition between two different effects. The first is the small difference in mass between up and down quarks, which is about 200 times less than the mass of the proton. The second is their different electric charges. The up quark has a charge of +2/3 in units of the proton charge, while ...

  15. [Acquisition of skills in medical ethics in learning-teaching small groups. Comparing problem-based learning with the traditional model]. (United States)

    Figueira, Eliandro José Gutierres; Cazzo, Everton; Tuma, Paula; Silva Filho, Carlos Rodrigues da; Conterno, Lucieni de Oliveira


    Aiming to evaluate the acquisition of skills on Medical Ethics among medical students from Marilia Medical School, some of them from the small group learning-teaching method, others from traditional teaching method. A prospective analytical study was done based on the application of questionnaires about general themes on Ethics, at two different times. There weren't significant differences on the skills' acquisition between the two methods. Students from late graduation years showed a significantly better performance than those from early years. The themes that presented worse results were medical secret, legal responsible consent, patient autonomy, medical prescription, medical handbook and corporative feeling in the presence of medical mistake. The most important difference between the groups was not the pedagogical pattern but the exposition time to the theme. PBL gives the chance to distribute the theme in different situations accelerating the acquisition of knowledge in Medical Ethics. It was realized that a revitalization on Medical Ethics teaching is necessary at our institution, aiming a better integration with the socio-economical situation in our country.

  16. 'My body is mine': Qualitatively exploring agency among internally displaced women participants in a small-group intervention in Leogane, Haiti. (United States)

    Logie, Carmen H; Daniel, CarolAnn


    The 2010 earthquake resulted in the breakdown of Haiti's social, economic and health infrastructure. Over one-quarter of a million people remain internally displaced (ID). ID women experience heightened vulnerability to intimate partner violence (IPV) due to increased poverty and reduced community networks. Scant research has examined experiences of IPV among ID women in post-earthquake Haiti. We conducted a qualitative study to explore the impact of participating in Famn an Aksyon Pou Santé Yo (FASY), a small-group HIV prevention intervention, on ID women's agency in Leogane, Haiti. We conducted four focus groups with ID women, FASY participants (n = 40) and in-depth individual interviews with peer health workers (n = 7). Our study was guided by critical ethnography and paid particular attention to power relations. Findings highlighted multiple forms of IPV (e.g., physical, sexual). Participants discussed processes of intrapersonal (confidence), interpersonal (communication), relational (support) and collective (women's rights) agency. Yet structural factors, including patriarchal gender norms and poverty, silenced IPV discussions and constrained women's agency. Findings suggest that agency among ID women is a multi-level, non-linear and incremental process. To effectively address IPV among ID women in Haiti, interventions should address structural contexts of gender inequity and poverty and concurrently facilitate multi-level processes of agency.

  17. Workplace Charging. Charging Up University Campuses

    Energy Technology Data Exchange (ETDEWEB)

    Giles, Carrie [ICF International, Fairfax, VA (United States); Ryder, Carrie [ICF International, Fairfax, VA (United States); Lommele, Stephen [National Renewable Energy Lab. (NREL), Golden, CO (United States)


    This case study features the experiences of university partners in the U.S. Department of Energy's (DOE) Workplace Charging Challenge with the installation and management of plug-in electric vehicle (PEV) charging stations.

  18. San Francisco Bay Area CHARG: Coastal Hazards Adaptation Resiliency Group, a Multi-Jurisdictional Collaboration to Develop Innovative Regional Solutions to Address Sea Level Rise and Improve Shoreline Resiliency (United States)

    Saleh, R.


    For a challenge as complex and far-reaching as sea level rise and improving shoreline resiliency, strong partnerships between scientists, elected officials, decision-makers, and the general public are the only way that effective solutions can be developed. The San Francisco Bay, like many similar sheltered water coastal environments (for example, Galveston Bay, Tampa Bay, or Venetian Lagoon) offers a unique opportunity for multiple jurisdictions to collaborate to address sea level rise on a regional basis. For the San Francisco Bay, significant scientific progress has been made in building a real-time simulation model for riverine and Bay hydrodynamics. Other major scientific initiatives, such as morphology mapping, shoreline mapping, and a sediment budget are also underway. In 2014, leaders from the Bay Area science, engineering, planning, policy, elected, and regulatory communities representing jurisdictions around the Bay joined together to address sea level rise. The group includes people from local, regional, state, and federal agencies and organizations. Together, CHARG (Coastal Hazards Adaptation Resiliency Group) established a collective vision and approach to implementing regional solutions. Decision-makers within many Bay Area jurisdictions are motivated to show demonstrable progress toward addressing sea level rise. However, the cost to implement shoreline resiliency solutions will be very large, and must be founded on strong science.CHARG is now tackling several key technical challenges. One is to develop science-based guidelines for local jurisdictions to determine when a project is local, sub-regional, or regional. Concurrently, several organizations are planning or implementing pilot shoreline resiliency projects and other programs. Many creative regional solutions are possible in a sheltered water environment that simply would not be feasible along the open coast. By definition, these solutions cannot be undertaken by one entity alone. Large

  19. Contextualizing the relevance of basic sciences: small-group simulation with debrief for first- and second-year medical students in an integrated curriculum

    Directory of Open Access Journals (Sweden)

    Ginzburg SB


    Full Text Available Samara B Ginzburg,1 Judith Brenner,1 Michael Cassara,2 Thomas Kwiatkowski,1 Joanne M Willey,1 1Department of Science Education, Hofstra Northwell School of Medicine, Hempstead, 2Department of Emergency Medicine, Northwell Health, Great Neck, NY, USA Aim: There has been a call for increased integration of basic and clinical sciences during ­preclinical years of undergraduate medical education. Despite the recognition that clinical simulation is an effective pedagogical tool, little has been reported on its use to demonstrate the relevance of basic science principles to the practice of clinical medicine. We hypothesized that simulation with an integrated science and clinical debrief used with early learners would illustrate the importance of basic science principles in clinical diagnosis and management of patients.  Methods: Small groups of first -and second-year medical students were engaged in a high-fidelity simulation followed by a comprehensive debrief facilitated by a basic scientist and clinician. Surveys including anchored and open-ended questions were distributed at the conclusion of each experience.  Results: The majority of the students agreed that simulation followed by an integrated debrief illustrated the clinical relevance of basic sciences (mean ± standard deviation: 93.8% ± 2.9% of first-year medical students; 96.7% ± 3.5% of second-year medical students and its importance in patient care (92.8% of first-year medical students; 90.4% of second-year medical students. In a thematic analysis of open-ended responses, students felt that these experiences provided opportunities for direct application of scientific knowledge to diagnosis and treatment, improving student knowledge, simulating real-world experience, and developing clinical reasoning, all of which specifically helped them understand the clinical relevance of basic sciences.  Conclusion: Small-group simulation followed by a debrief that integrates basic and clinical

  20. O pequeno grupo "Oficina de Capoeira" no contexto da reforma psiquiátrica The small "Capoeira Workshop" group in the context of psychiatric reform

    Directory of Open Access Journals (Sweden)

    Míriam Cristiane Alves


    Full Text Available A Oficina de Capoeira nasceu a partir da necessidade de inter-relação entre o Hospital Psiquiátrico São Pedro e a Vila São Pedro, haja vista a construção dos Serviços Residenciais Terapêuticos em parte da área territorial da vila. Composta de moradores da vila e usuários do hospital, esta oficina foi escolhida como objeto de estudo devido a sua singularidade, diversidade e contextualização na reforma psiquiátrica. Este estudo objetiva esclarecer como se produz e se organiza o sistema Pequeno Grupo Oficina de Capoeira, utilizando como principal referencial o Paradigma da Complexidade de Edgar Morin. As informações foram registradas a partir de observações e anotações em diário de campo. Participaram da pesquisa os sujeitos que constituíram a Oficina de Capoeira. Esta proposta nos sugere outras possibilidades de intervenção em pequenos grupos no contexto da reforma psiquiátrica. Todavia, precisamos viver a heterogeneidade e a incerteza do sistema como possibilidade de produção de sujeitos criativos.The Capoeira workshop was formed from the need to strengthen the relationship between the Hospital Psiquiátrico São Pedro and the Vila São Pedro neighborhood, considering the construction of the Residential Therapeutic Services unit in the neighborhood. Composed of local residents and users of the hospital, the workshop was chosen as an object of study due to its uniqueness, its diversity and for the way it places psychiatric reform in context. The study aimed to understand how the small Capoeira Workshop group is produced and organized. The principal theoretical reference for the study was the Complexity Paradigm of Edgar Morin. The data was collected from observations and notations in a field notebook. Study participants included the subjects who composed the Capoeira Workshop. This created other possibilities for intervention in small groups in the context of psychiatric reform. Nevertheless, we need to experience the

  1. Point charges optimally placed to represent the multipole expansion of charge distributions.

    Directory of Open Access Journals (Sweden)

    Ramu Anandakrishnan

    Full Text Available We propose an approach for approximating electrostatic charge distributions with a small number of point charges to optimally represent the original charge distribution. By construction, the proposed optimal point charge approximation (OPCA retains many of the useful properties of point multipole expansion, including the same far-field asymptotic behavior of the approximate potential. A general framework for numerically computing OPCA, for any given number of approximating charges, is described. We then derive a 2-charge practical point charge approximation, PPCA, which approximates the 2-charge OPCA via closed form analytical expressions, and test the PPCA on a set of charge distributions relevant to biomolecular modeling. We measure the accuracy of the new approximations as the RMS error in the electrostatic potential relative to that produced by the original charge distribution, at a distance 2x the extent of the charge distribution--the mid-field. The error for the 2-charge PPCA is found to be on average 23% smaller than that of optimally placed point dipole approximation, and comparable to that of the point quadrupole approximation. The standard deviation in RMS error for the 2-charge PPCA is 53% lower than that of the optimal point dipole approximation, and comparable to that of the point quadrupole approximation. We also calculate the 3-charge OPCA for representing the gas phase quantum mechanical charge distribution of a water molecule. The electrostatic potential calculated by the 3-charge OPCA for water, in the mid-field (2.8 Å from the oxygen atom, is on average 33.3% more accurate than the potential due to the point multipole expansion up to the octupole order. Compared to a 3 point charge approximation in which the charges are placed on the atom centers, the 3-charge OPCA is seven times more accurate, by RMS error. The maximum error at the oxygen-Na distance (2.23 Å is half that of the point multipole expansion up to the octupole

  2. A positionism epitomology applied to small group decision-making in radioactive waste management. Doctoral thesis prepared at SCK-CEN and defended in 2004

    International Nuclear Information System (INIS)

    Bombaerts, G.


    The article refers to an abstract of a doctoral thesis. Assuring the safety of technological developments is becoming one of the most important tasks in society. For nuclear waste repositories, it is important to know what will remain valuable of current performance and safety assessments within a few hundred years. The core of the PhD concerns the meaning that can be attributed to safety assessments. This study develops a new philosophical theory to explain how small group decision-making on technoscientific problems takes place. It is applied to the specific problem of decision-making on radioactive waste disposal and its related risk assessment. The new philosophical theory is based on Latour's interactionism theory, which in its essence states that facts are only facts if they are accepted by the network. The theory adds that fact-building or decision-making happens in a certain context by interaction of different context elements. The word context has a very specific meaning. It refers to a problem solving situations in which individuals work out a problem framing and use attitudes, personalities, group cultures, and objects. Decisions or fact-building within the group will happen by interaction between these context elements that will get different hierarchical positions and lead to contextual dissonance reduction. This is called positionism. An international questionnaire has been carried out asking for estimations by technologists and scientists of the risks and uncertainties of a high level waste repository on the one hand and their personality, group culture and background characteristics on the other hand. Two important indicators occur. High neuroticism -a personality measure indicating the general tendency to experience affects such as fear, sadness, or distrust- correlates with high assessments of the waste repository risks. Scientists with high confidence in science give significant lower estimations of the repository risks. These results illustrate

  3. Common arm comparative outcomes analysis of phase 3 trials of cisplatin + irinotecan versus cisplatin + etoposide in extensive stage small cell lung cancer: final patient-level results from Japan Clinical Oncology Group 9511 and Southwest Oncology Group 0124. (United States)

    Lara, Primo N; Chansky, Kari; Shibata, Taro; Fukuda, Haruhiko; Tamura, Tomohide; Crowley, John; Redman, Mary W; Natale, Ronald; Saijo, Nagahiro; Gandara, David R


    Southwest Oncology Group 0124 was a large North American phase 3 trial that failed to confirm a survival benefit for cisplatin/irinotecan over cisplatin/etoposide in patients with extensive stage small cell lung cancer (SCLC). These results were contrary to Japan Clinical Oncology Group 9511, a phase 3 trial exclusively in Japanese patients. Because 0124 and 9511 used identical treatment regimens and similar eligibility criteria, patient-level data were pooled from both trials, and a common arm analysis was performed to explore potential reasons for the divergent results. Patients with documented extensive stage SCLC and adequate end-organ function were randomized to intravenously receive either cisplatin 60 mg/m(2) Day 1 + irinotecan 60 mg/m(2) Days 1, 8, and 15 every 4 weeks or cisplatin 80 mg/m(2) Day 1 + etoposide 100 mg/m(2) Days 1-3 every 3 weeks. Demographic and outcome data were compared among 805 patients enrolled in 9511 and 0124 receiving identical treatment using a logistic model adjusted for age, sex, and performance status (PS). Of 671 patients in 0124, 651 eligible patients were included, as were all 154 patients from 9511. Significant differences in sex and PS distribution as well as toxicity were seen between trials. There were also significant differences in response rates (87% vs 60%, Pglobalization, warrant: 1) consideration of differential patient characteristics and outcomes among populations receiving identical therapy; 2) utilization of the common arm model in prospective trials; and 3) inclusion of pharmacogenomic correlates in cancer trials where ethnic/racial differences in drug disposition are expected. Copyright © 2010 American Cancer Society.


    Energy Technology Data Exchange (ETDEWEB)

    Muñoz-Jaramillo, Andrés; Windmueller, John C.; Amouzou, Ernest C.; Longcope, Dana W. [Department of Physics, Montana State University, Bozeman, MT 59717 (United States); Senkpeil, Ryan R. [Department of Physics, Purdue University, West Lafayette, IN 47907 (United States); Tlatov, Andrey G. [Kislovodsk Mountain Astronomical Station of the Pulkovo Observatory, Kislovodsk 357700 (Russian Federation); Nagovitsyn, Yury A. [Pulkovo Astronomical Observatory, Russian Academy of Sciences, St. Petersburg 196140 (Russian Federation); Pevtsov, Alexei A. [National Solar Observatory, Sunspot, NM 88349 (United States); Chapman, Gary A.; Cookson, Angela M. [San Fernando Observatory, Department of Physics and Astronomy, California State University Northridge, Northridge, CA 91330 (United States); Yeates, Anthony R. [Department of Mathematical Sciences, Durham University, South Road, Durham DH1 3LE (United Kingdom); Watson, Fraser T. [National Solar Observatory, Tucson, AZ 85719 (United States); Balmaceda, Laura A. [Institute for Astronomical, Terrestrial and Space Sciences (ICATE-CONICET), San Juan (Argentina); DeLuca, Edward E. [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA 02138 (United States); Martens, Petrus C. H., E-mail: [Department of Physics and Astronomy, Georgia State University, Atlanta, GA 30303 (United States)


    In this work, we take advantage of 11 different sunspot group, sunspot, and active region databases to characterize the area and flux distributions of photospheric magnetic structures. We find that, when taken separately, different databases are better fitted by different distributions (as has been reported previously in the literature). However, we find that all our databases can be reconciled by the simple application of a proportionality constant, and that, in reality, different databases are sampling different parts of a composite distribution. This composite distribution is made up by linear combination of Weibull and log-normal distributions—where a pure Weibull (log-normal) characterizes the distribution of structures with fluxes below (above) 10{sup 21}Mx (10{sup 22}Mx). Additionally, we demonstrate that the Weibull distribution shows the expected linear behavior of a power-law distribution (when extended to smaller fluxes), making our results compatible with the results of Parnell et al. We propose that this is evidence of two separate mechanisms giving rise to visible structures on the photosphere: one directly connected to the global component of the dynamo (and the generation of bipolar active regions), and the other with the small-scale component of the dynamo (and the fragmentation of magnetic structures due to their interaction with turbulent convection)

  5. A case-based, small-group cooperative learning course in preclinical veterinary science aimed at bridging basic science and clinical literacy. (United States)

    Schoeman, J P; van Schoor, M; van der Merwe, L L; Meintjes, R A


    In 1999 a dedicated problem-based learning course was introduced into the lecture-based preclinical veterinary curriculum of the University of Pretoria. The Introduction to Clinical Studies Course combines traditional lectures, practical sessions, student self-learning and guided tutorials. The self-directed component of the course utilises case-based, small-group cooperative learning as an educational vehicle to link basic science with clinical medicine. The aim of this article is to describe the objectives and structure of the course and to report the results of the assessment of the students' perceptions on some aspects of the course. Students reacted very positively to the ability of the course to equip them with problem-solving skills. Students indicated positive perceptions about the workload of the course. There were, however, significantly lower scores for the clarity of the course objectives. Although the study guide for the course is very comprehensive, the practice regarding the objectives is still uncertain. It is imperative to set clear objectives in non-traditional, student-centred courses. The objectives have to be explained at the outset and reiterated throughout the course. Tutors should also communicate the rationale behind problem-based learning as a pedagogical method to the students. Further research is needed to verify the effectiveness of this course in bridging the gap between basic science and clinical literacy in veterinary science. Ongoing feedback and assessment of the management and content are important to refine this model for integrating basic science with clinical literacy.

  6. Small-Group Randomized Controlled Trial to Increase Condom Use and HIV Testing Among Hispanic/Latino Gay, Bisexual, and Other Men Who Have Sex With Men. (United States)

    Rhodes, Scott D; Alonzo, Jorge; Mann, Lilli; Song, Eunyoung Y; Tanner, Amanda E; Arellano, Jorge Elias; Rodriguez-Celedon, Rodrigo; Garcia, Manuel; Freeman, Arin; Reboussin, Beth A; Painter, Thomas M


    To evaluate the HOLA en Grupos intervention, a Spanish-language small-group behavioral HIV prevention intervention designed to increase condom use and HIV testing among Hispanic/Latino gay, bisexual, and other men who have sex with men. In 2012 to 2015, we recruited and randomized 304 Hispanic/Latino men who have sex with men, aged 18 to 55 years in North Carolina, to the 4-session HOLA en Grupos intervention or an attention-equivalent general health education comparison intervention. Participants completed structured assessments at baseline and 6-month follow-up. Follow-up retention was 100%. At follow-up, relative to comparison participants, HOLA en Grupos participants reported increased consistent condom use during the past 3 months (adjusted odds ratio [AOR] = 4.1; 95% confidence interval [CI] = 2.2, 7.9; P HOLA en Grupos participants also reported increased knowledge of HIV (P HOLA en Grupos intervention is efficacious for reducing HIV risk behaviors among Hispanic/Latino men who have sex with men.

  7. Cosmology of a charged universe

    International Nuclear Information System (INIS)

    Barnes, A.


    The Proca generalization of electrodynamics admits the possibility that the universe could possess a net electric charge uniformly distributed throughout space, while possessing no electric field. A charged intergalactic (and intragalactic) medium of this kind could contain enough energy to be of cosmological importance. A general-relativistic model of cosmological expansion dominated by such a charged background has been calculated, and is consistent with present observational limits on the Hubble constant, the decleration parameter, and the age of the universe. However, if this cosmology applied at the present epoch, the very early expansion of the universe would have been much more rapid than in conventional ''big bang'' cosmologies, too rapid for cosmological nucleosynthesis or thermalization of the background radiation to have occurred. Hence, domination of the present expansion by background charge appears to be incompatible with the 3 K background and big-bang production of light elements. If the present background charge density were sufficiently small (but not strictly zero), expansion from the epoch of nucleosynthesis would proceed according to the conventional scenario, but the energy due to the background charge would have dominated at some earlier epoch. This last possibility leads to equality of pressure and energy density in the primordial universe, a condition of special significance in certain cosmological theories

  8. The efficacy of the well of the well (WOW) culture system on development of bovine embryos in a small group and the effect of number of adjacent embryos on their development.


    Kang, Sung-Sik; Ofuji, Sosuke; Imai, Kei; Huang, Weiping; Koyama, Keisuke; Yanagawa, Yojiro; Takahashi, Yoshiyuki; Nagano, Masashi


    The aim of the present study was to clarify the efficacy of the well of the well (WOW) culture system for a small number of embryos and the effect of number of adjacent embryos in a WOW dish on blastocyst development. In conventional droplet culture, embryos in the small-number group (5-6 embryos/droplet) showed low blastocyst development compared with a control group (25-26 embryos/droplet). However, small and large numbers of embryos (5-6 and 25 embryos, respectively) in a WOW dish showed n...

  9. Charged boson stars (United States)

    Pugliese, Daniela; Quevedo, Hernando; Rueda H., Jorge A.; Ruffini, Remo


    We study time-independent, spherically symmetric, self-gravitating systems minimally coupled to a scalar field with U(1) gauge symmetry: charged boson stars. We find numerical solutions to the Einstein-Maxwell equations coupled to the relativistic Klein-Gordon equation. It is shown that bound stable configurations exist only for values of the coupling constant less than or equal to a certain critical value. The metric coefficients and the relevant physical quantities, such as the total mass and charge, turn out to be, in general, bound functions of the radial coordinate, reaching their maximum values at a critical value of the scalar field at the origin. We discuss the stability problem from both the quantitative and qualitative point of view. We take into account the electromagnetic contribution to the total mass and investigate the stability issue considering the binding energy per particle. We verify the existence of configurations with positive binding energy in which objects that are apparently bound can be unstable against small perturbations, in full analogy with the effect observed in the mass-radius relation of neutron stars.

  10. Gender, Race, and Survival: A Study in Non-Small-Cell Lung Cancer Brain Metastases Patients Utilizing the Radiation Therapy Oncology Group Recursive Partitioning Analysis Classification

    International Nuclear Information System (INIS)

    Videtic, Gregory M.M.; Reddy, Chandana A.; Chao, Samuel T.; Rice, Thomas W.; Adelstein, David J.; Barnett, Gene H.; Mekhail, Tarek M.; Vogelbaum, Michael A.; Suh, John H.


    Purpose: To explore whether gender and race influence survival in non-small-cell lung cancer (NSCLC) in patients with brain metastases, using our large single-institution brain tumor database and the Radiation Therapy Oncology Group recursive partitioning analysis (RPA) brain metastases classification. Methods and materials: A retrospective review of a single-institution brain metastasis database for the interval January 1982 to September 2004 yielded 835 NSCLC patients with brain metastases for analysis. Patient subsets based on combinations of gender, race, and RPA class were then analyzed for survival differences. Results: Median follow-up was 5.4 months (range, 0-122.9 months). There were 485 male patients (M) (58.4%) and 346 female patients (F) (41.6%). Of the 828 evaluable patients (99%), 143 (17%) were black/African American (B) and 685 (83%) were white/Caucasian (W). Median survival time (MST) from time of brain metastasis diagnosis for all patients was 5.8 months. Median survival time by gender (F vs. M) and race (W vs. B) was 6.3 months vs. 5.5 months (p = 0.013) and 6.0 months vs. 5.2 months (p = 0.08), respectively. For patients stratified by RPA class, gender, and race, MST significantly favored BFs over BMs in Class II: 11.2 months vs. 4.6 months (p = 0.021). On multivariable analysis, significant variables were gender (p = 0.041, relative risk [RR] 0.83) and RPA class (p < 0.0001, RR 0.28 for I vs. III; p < 0.0001, RR 0.51 for II vs. III) but not race. Conclusions: Gender significantly influences NSCLC brain metastasis survival. Race trended to significance in overall survival but was not significant on multivariable analysis. Multivariable analysis identified gender and RPA classification as significant variables with respect to survival.

  11. Modeling Local Control After Hypofractionated Stereotactic Body Radiation Therapy for Stage I Non-Small Cell Lung Cancer: A Report From the Elekta Collaborative Lung Research Group

    Energy Technology Data Exchange (ETDEWEB)

    Ohri, Nitin, E-mail: [Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania (United States); Werner-Wasik, Maria [Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania (United States); Grills, Inga S. [Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan (United States); Belderbos, Jose [Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam (Netherlands); Hope, Andrew [Department of Radiation Oncology, Princess Margaret Hospital and University of Toronto, Toronto, ON (Canada); Yan Di; Kestin, Larry L. [Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan (United States); Guckenberger, Matthias [Department of Radiation Oncology, University of Wuerzburg, Wuerzburg (Germany); Sonke, Jan-Jakob [Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam (Netherlands); Bissonnette, Jean-Pierre [Department of Radiation Oncology, Princess Margaret Hospital and University of Toronto, Toronto, ON (Canada); Xiao, Ying [Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania (United States)


    Purpose: Hypofractionated stereotactic body radiation therapy (SBRT) has emerged as an effective treatment option for early-stage non-small cell lung cancer (NSCLC). Using data collected by the Elekta Lung Research Group, we generated a tumor control probability (TCP) model that predicts 2-year local control after SBRT as a function of biologically effective dose (BED) and tumor size. Methods and Materials: We formulated our TCP model as follows: TCP = e{sup [BED10-c Asterisk-Operator L-TCD50]/k} Division-Sign (1 + e{sup [BED10-c Asterisk-Operator L-TCD50]/k}), where BED10 is the biologically effective SBRT dose, c is a constant, L is the maximal tumor diameter, and TCD50 and k are parameters that define the shape of the TCP curve. Least-squares optimization with a bootstrap resampling approach was used to identify the values of c, TCD50, and k that provided the best fit with observed actuarial 2-year local control rates. Results: Data from 504 NSCLC tumors treated with a variety of SBRT schedules were available. The mean follow-up time was 18.4 months, and 26 local recurrences were observed. The optimal values for c, TCD50, and k were 10 Gy/cm, 0 Gy, and 31 Gy, respectively. Thus, size-adjusted BED (sBED) may be defined as BED minus 10 times the tumor diameter (in centimeters). Our TCP model indicates that sBED values of 44 Gy, 69 Gy, and 93 Gy provide 80%, 90%, and 95% chances of tumor control at 2 years, respectively. When patients were grouped by sBED, the model accurately characterized the relationship between sBED and actuarial 2-year local control (r=0.847, P=.008). Conclusion: We have developed a TCP model that predicts 2-year local control rate after hypofractionated SBRT for early-stage NSCLC as a function of biologically effective dose and tumor diameter. Further testing of this model with additional datasets is warranted.

  12. Chemical analysis of carbon stars in the local group - l.  The small magnetic cloud and the Sagittarius Dwarf Spheroidal galaxy

    DEFF Research Database (Denmark)

    de Laverny...[], P.; Abia, C.; Dominguez, I


    Stars: abundances, stars: carbon, nuclear reactions, nucleosynthesis, abundances, galaxies: Local Group Udgivelsesdato: Feb.......Stars: abundances, stars: carbon, nuclear reactions, nucleosynthesis, abundances, galaxies: Local Group Udgivelsesdato: Feb....

  13. Review of Variable Generation Integration Charges

    Energy Technology Data Exchange (ETDEWEB)

    Porter, K.; Fink, S.; Buckley, M.; Rogers, J.; Hodge, B. M.


    The growth of wind and solar generation in the United States, and the expectation of continued growth of these technologies, dictates that the future power system will be operated in a somewhat different manner because of increased variability and uncertainty. A small number of balancing authorities have attempted to determine an 'integration cost' to account for these changes to their current operating practices. Some balancing authorities directly charge wind and solar generators for integration charges, whereas others add integration charges to projected costs of wind and solar in integrated resource plans or in competitive solicitations for generation. This report reviews the balancing authorities that have calculated variable generation integration charges and broadly compares and contrasts the methodologies they used to determine their specific integration charges. The report also profiles each balancing authority and how they derived wind and solar integration charges.

  14. Liquid-drop model for fragmentation of multiply charged mercury clusters. (United States)

    Nakamura, Masato; Tarento, René-Jean


    The fragmentation of doubly and triply charged mercury clusters is theoretically studied to analyze an experiment performed by Katakuse's group at Osaka University [T. Satoh et al., J. Mass Spectrom. Soc. Jpn. 51, 391 (2003)]. The fission barrier is calculated using a liquid-drop model proposed by Echt et al. In the decay of doubly charged clusters, the barrier height is found to take the minimum value for nearly symmetric fission. On the other hand, in the decay of triply charged clusters, the barrier is the lowest for strongly asymmetric fission. These results well explain the product size distribution observed in the experiment. The appearance size for multiply charged clusters measured in the experiment is found to be the size where the fission barrier is equal to the monomer evaporation energy. These findings provide evidence that small mercury clusters behave like van der Waals clusters in the process of fragmentation.

  15. Tokamak rotation and charge exchange

    International Nuclear Information System (INIS)

    Hazeltine, R.D.; Rowan, W.L.; Solano, E.R.; Valanju, P.M.


    In the absence of momentum input, tokamak toroidal rotation rates are typically small - no larger in particular than poloidal rotation - even when the radial electric field is strong, as near the plasma edge. This circumstance, contradicting conventional neoclassical theory, is commonly attributed to the rotation damping effect of charge exchange, although a detailed comparison between charge-exchange damping theory and experiment is apparently unavailable. Such a comparison is attempted here in the context of recent TEXT experiments, which compare rotation rates, both poloidal and toroidal, in helium and hydrogen discharges. The helium discharges provide useful data because they are nearly free of ion-neutral charge exchange; they have been found to rotate toroidally in reasonable agreement with neoclassical predictions. The hydrogen experiments show much smaller toroidal motion as usual. The theoretical calculation uses the full charge-exchange operator and assumes plateau collisionality, roughly consistent with the experimental conditions. The authors calculate the ion flow as a function of v cx /v c , where v cx is the charge exchange rate and v c the Coulomb collision frequency. The results are in reasonable accord with the observations. 1 ref

  16. Byers Auto Group: A Case Study Into The Economics, Zoning, and Overall Process of Installing Small Wind Turbines at Two Automotive Dealerships in Ohio

    Energy Technology Data Exchange (ETDEWEB)

    Oteri, F.; Sinclair, K.


    This paper provides the talking points about a case study on the installation of a $600,000 small wind project, the installation process, estimated annual energy production and percentage of energy needs met by the turbines.

  17. Preface: Charge transport in nanoscale junctions (United States)

    Albrecht, Tim; Kornyshev, Alexei; Bjørnholm, Thomas


    Understanding the fundamentals of nanoscale charge transfer is pivotal for designing future nano-electronic devices. Such devices could be based on individual or groups of molecular bridges, nanotubes, nanoparticles, biomolecules and other 'active' components, mimicking wire, diode and transistor functions. These have operated in various environments including vacuum, air and condensed matter, in two- or three-electrode configurations, at ultra-low and room temperatures. Interest in charge transport in ultra-small device components has a long history and can be dated back to Aviram and Ratner's letter in 1974 (Chem. Phys. Lett. 29 277-83). So why is there a necessity for a special issue on this subject? The area has reached some degree of maturity, and even subtle geometric effects in the nanojunction and noise features can now be resolved and rationalized based on existing theoretical concepts. One purpose of this special issue is thus to showcase various aspects of nanoscale and single-molecule charge transport from experimental and theoretical perspectives. The main principles have 'crystallized' in our minds, but there is still a long way to go before true single-molecule electronics can be implemented. Major obstacles include the stability of electronic nanojunctions, reliable operation at room temperature, speed of operation and, last but not least, integration into large networks. A gradual transition from traditional silicon-based electronics to devices involving a single (or a few) molecule(s) therefore appears to be more viable from technologic and economic perspectives than a 'quantum leap'. As research in this area progresses, new applications emerge, e.g. with a view to characterizing interfacial charge transfer at the single-molecule level in general. For example, electrochemical experiments with individual enzyme molecules demonstrate that catalytic processes can be studied with nanometre resolution, offering a route towards optimizing biosensors at

  18. Design of asymmetric particles containing a charged interior and a neutral surface charge: comparative study on in vivo circulation of polyelectrolyte microgels. (United States)

    Chen, Kai; Xu, Jing; Luft, J Christopher; Tian, Shaomin; Raval, Jay S; DeSimone, Joseph M


    Lowering the modulus of hydrogel particles could enable them to bypass in vivo physical barriers that would otherwise filter particles with similar size but higher modulus. Incorporation of electrolyte moieties into the polymer network of hydrogel particles to increase the swelling ratio is a straightforward and quite efficient way to decrease the modulus. In addition, charged groups in hydrogel particles can also help secure cargoes. However, the distribution of charged groups on the surface of a particle can accelerate the clearance of particles. Herein, we developed a method to synthesize highly swollen microgels of precise size with near-neutral surface charge while retaining interior charged groups. A strategy was employed to enable a particle to be highly cross-linked with very small mesh size, and subsequently PEGylated to quench the exterior amines only without affecting the internal amines. Acidic degradation of the cross-linker allows for swelling of the particles to microgels with a desired size and deformability. The microgels fabricated demonstrated extended circulation in vivo compared to their counterparts with a charged surface, and could potentially be utilized in in vivo applications including as oxygen carriers or nucleic acid scavengers.

  19. Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group. (United States)

    Breton, Carrie V; Marsit, Carmen J; Faustman, Elaine; Nadeau, Kari; Goodrich, Jaclyn M; Dolinoy, Dana C; Herbstman, Julie; Holland, Nina; LaSalle, Janine M; Schmidt, Rebecca; Yousefi, Paul; Perera, Frederica; Joubert, Bonnie R; Wiemels, Joseph; Taylor, Michele; Yang, Ivana V; Chen, Rui; Hew, Kinjal M; Freeland, Deborah M Hussey; Miller, Rachel; Murphy, Susan K


    Characterization of the epigenome is a primary interest for children's environmental health researchers studying the environmental influences on human populations, particularly those studying the role of pregnancy and early-life exposures on later-in-life health outcomes. Our objective was to consider the state of the science in environmental epigenetics research and to focus on DNA methylation and the collective observations of many studies being conducted within the Children's Environmental Health and Disease Prevention Research Centers, as they relate to the Developmental Origins of Health and Disease (DOHaD) hypothesis. We address the current laboratory and statistical tools available for epigenetic analyses, discuss methods for validation and interpretation of findings, particularly when magnitudes of effect are small, question the functional relevance of findings, and discuss the future for environmental epigenetics research. A common finding in environmental epigenetic studies is the small-magnitude epigenetic effect sizes that result from such exposures. Although it is reasonable and necessary that we question the relevance of such small effects, we present examples in which small effects persist and have been replicated across populations and across time. We encourage a critical discourse on the interpretation of such small changes and further research on their functional relevance for children's health. The dynamic nature of the epigenome will require an emphasis on future longitudinal studies in which the epigenome is profiled over time, over changing environmental exposures, and over generations to better understand the multiple ways in which the epigenome may respond to environmental stimuli.


    African Journals Online (AJOL)


    dissociation of these groups, result into a pH dependent surface charge whose density can be measured by acid-base titration. The surface charge density determined by such method is essentially measured relative to the unknown condition of the oxide/liquid interface prior to reagent addition (i.e. at the point of zero ...


    Energy Technology Data Exchange (ETDEWEB)

    Van Ranst, Eric; Qafoku, Nikolla; Noble, Andrew; Xu, Ren-Kou


    Soils rich in particles with amphoteric surface properties in the Oxisols, Ultisols, Alfisols, Spodosols and Andisols orders (1) are considered to be variable charge soils (2) (Table 1). The term “variable charge” is used to describe organic and inorganic soil constituents with reactive surface groups whose charge varies with pH and ionic concentration and composition of the soil solution. Such groups are the surface carboxyl, phenolic and amino functional groups of organic materials in soils, and surface hydroxyl groups of Fe and Al oxides, allophane and imogolite. The hydroxyl surface groups are also present on edges of some phyllosilicate minerals such as kaolinite, mica, and hydroxyl-interlayered vermiculite. The variable charge is developed on the surface groups as a result of adsorption or desorption of ions that are constituents of the solid phase, i.e., H+, and the adsorption or desorption of solid-unlike ions that are not constituents of the solid phase. Highly weathered soils and subsoils (e.g., Oxisols and some Ultisols, Alfisols and Andisols) may undergo isoelectric weathering and reach a “zero net charge” stage during their development. They usually have a slightly acidic to acidic soil solution pH, which is close to either the point of zero net charge (PZNC) (3) or the point of zero salt effect (PZSE) (3). They are characterized by high abundances of minerals with a point of zero net proton charge (PZNPC) (3) at neutral and slightly basic pHs; the most important being Fe and Al oxides and allophane. Under acidic conditions, the surfaces of these minerals are net positively charged. In contrast, the surfaces of permanent charge phyllosilicates are negatively charged regardless of ambient conditions. Variable charge soils therefore, are heterogeneous charge systems.

  2. Linear shaped charge

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, David; Stofleth, Jerome H.; Saul, Venner W.


    Linear shaped charges are described herein. In a general embodiment, the linear shaped charge has an explosive with an elongated arrowhead-shaped profile. The linear shaped charge also has and an elongated v-shaped liner that is inset into a recess of the explosive. Another linear shaped charge includes an explosive that is shaped as a star-shaped prism. Liners are inset into crevices of the explosive, where the explosive acts as a tamper.

  3. Charge Orbits of Extremal Black Holes in Five Dimensional Supergravity

    CERN Document Server

    Cerchiai, Bianca L; Marrani, Alessio; Zumino, Bruno


    We derive the U-duality charge orbits, as well as the related moduli spaces, of "large" and "small" extremal black holes in non-maximal ungauged Maxwell-Einstein supergravities with symmetric scalar manifolds in d=5 space-time dimensions. The stabilizer groups of the various classes of orbits are obtained by determining and solving suitable U-invariant sets of constraints, both in "bare" and "dressed" charges bases, with various methods. After a general treatment of attractors in real special geometry (also considering non-symmetric cases), the N=2 "magic" theories, as well as the N=2 Jordan symmetric sequence, are analyzed in detail. Finally, the half-maximal (N=4) matter-coupled supergravity is also studied in this context.

  4. Efficacy of an internet-based learning module and small-group debriefing on trainees' attitudes and communication skills toward patients with substance use disorders: results of a cluster randomized controlled trial. (United States)

    Lanken, Paul N; Novack, Dennis H; Daetwyler, Christof; Gallop, Robert; Landis, J Richard; Lapin, Jennifer; Subramaniam, Geetha A; Schindler, Barbara A


    To examine whether an Internet-based learning module and small-group debriefing can improve medical trainees' attitudes and communication skills toward patients with substance use disorders (SUDs). In 2011-2012, 129 internal and family medicine residents and 370 medical students at two medical schools participated in a cluster randomized controlled trial, which assessed the effect of adding a two-part intervention to the SUDs curricula. The intervention included a self-directed, media-rich Internet-based learning module and a small-group, faculty-led debriefing. Primary study outcomes were changes in self-assessed attitudes in the intervention group (I-group) compared with those in the control group (C-group) (i.e., a difference of differences). For residents, the authors used real-time, Web-based interviews of standardized patients to assess changes in communication skills. Statistical analyses, conducted separately for residents and students, included hierarchical linear modeling, adjusted for site, participant type, cluster, and individual scores at baseline. The authors found no significant differences between the I- and C-groups in attitudes for residents or students at baseline. Compared with those in the C-group, residents, but not students, in the I-group had more positive attitudes toward treatment efficacy and self-efficacy at follow-up (Pcommunication skills toward patients with SUDs among residents. Enhanced attitudes and skills may result in improved care for these patients.

  5. Spacecraft Charging Technology, 1980 (United States)


    The third Spacecraft Charging Technology Conference proceedings contain 66 papers on the geosynchronous plasma environment, spacecraft modeling, charged particle environment interactions with spacecraft, spacecraft materials characterization, and satellite design and testing. The proceedings is a compilation of the state of the art of spacecraft charging and environmental interaction phenomena.

  6. On equilibrium charge distribution above dielectric surface

    Directory of Open Access Journals (Sweden)

    Yu.V. Slyusarenko


    Full Text Available The problem of the equilibrium state of the charged many-particle system above dielectric surface is formulated. We consider the case of the presence of the external attractive pressing field and the case of its absence. The equilibrium distributions of charges and the electric field, which is generated by these charges in the system in the case of ideally plane dielectric surface, are obtained. The solution of electrostatic equations of the system under consideration in case of small spatial heterogeneities caused by the dielectric surface, is also obtained. These spatial inhomogeneities can be caused both by the inhomogeneities of the surface and by the inhomogeneous charge distribution upon it. In particular, the case of the "wavy" spatially periodic surface is considered taking into account the possible presence of the surface charges.

  7. The efficacy of the well of the well (WOW) culture system on development of bovine embryos in a small group and the effect of number of adjacent embryos on their development. (United States)

    Kang, Sung-Sik; Ofuji, Sosuke; Imai, Kei; Huang, Weiping; Koyama, Keisuke; Yanagawa, Yojiro; Takahashi, Yoshiyuki; Nagano, Masashi


    The aim of the present study was to clarify the efficacy of the well of the well (WOW) culture system for a small number of embryos and the effect of number of adjacent embryos in a WOW dish on blastocyst development. In conventional droplet culture, embryos in the small-number group (5-6 embryos/droplet) showed low blastocyst development compared with a control group (25-26 embryos/droplet). However, small and large numbers of embryos (5-6 and 25 embryos, respectively) in a WOW dish showed no significant differences in cleavage, blastocyst rates, and mean cell number in blastocysts compared with the control group (25-30 embryos/droplet). In addition, the number of adjacent embryos in a WOW dish did not affect the development to blastocysts and cell number in blastocysts. In conclusion, a WOW dish can provide high and stable blastocyst development in small group culture wherever embryos are placed in microwells of the WOW dish.

  8. Mechanism of stimulated radiation by charged particles

    International Nuclear Information System (INIS)

    Zachary, W.W.


    We have studied the mechanism for radiation by charged particles called stimulated electromagnetic shock radiation (SESR) by Schneider and Spitzer caused by the interaction between a relativistic charged particle and an externally applied electromagnetic plane wave in a dielectric. The present theory predicts that the SESR effect is large when the frequency of the plane wave lies in the microwave region but is small at higher frequencies for plane-wave field strengths smaller than the breakdown field of the dielectric

  9. Rebounding of a shaped-charge jet (United States)

    Proskuryakov, E. V.; Sorokin, M. V.; Fomin, V. M.


    The phenomenon of rebounding of a shaped-charge jet from the armour surface with small angles between the jet axis and the target surface is considered. Rebounding angles as a function of jet velocity are obtained in experiments for a copper shaped-charge jet. An engineering calculation technique is developed. The results calculated with the use of this technique are in reasonable agreement with experimental data.

  10. Charged particle detector

    International Nuclear Information System (INIS)

    Hagen, R.D.


    A device for detecting the emission of charged particles from a specimen is described. The specimen is placed within an accumulator means which statically accumulates any charged particles emitted from the specimen. The accumulator means is pivotally positioned between a first capacitor plate having a positive electrical charge and a second capacitor plate having a negative electrical charge. The accumulator means is attracted to one capacitor plate and repelled from the other capacitor plate by an amount proportional to the amount and intensity of charged particles emitted by the specimen. (auth)

  11. Space Charge Effects

    CERN Document Server

    Ferrario, M.; Palumbo, L.


    The space charge forces are those generated directly by the charge distribution, with the inclusion of the image charges and currents due to the interaction of the beam with a perfectly conducting smooth pipe. Space charge forces are responsible for several unwanted phenomena related to beam dynamics, such as energy loss, shift of the synchronous phase and frequency , shift of the betatron frequencies, and instabilities. We will discuss in this lecture the main feature of space charge effects in high-energy storage rings as well as in low-energy linacs and transport lines.


    Directory of Open Access Journals (Sweden)

    Dominik Zimon


    Full Text Available Purpose - The purpose of this paper is to ask one question. How the implementation of the requirements of ISO 9001 system affects the costs of running the business? Design/methodology/approach - The research covered time from 2006 to 2011 and was an attempt to assess the impact of the maintenance of the ISO 9001 Quality Management System on the costs of small and medium sized business organizations. The main objective was the selection of right research subjects that would allow the formulation of the most reliable and statistically valid conclusions. For this purpose we obtained permissions to conduct research in organizations characterized by comparable futures such as size, industry, type of business and strategy. Findings - The study shows that the costs associated with the implementation and maintenance of the Quality Management System standard is still too high, and effectively discourages representatives of small and medium-sized commercial organizations from implementing ISO 9001 system.

  13. Tirapazamine plus cisplatin versus cisplatin in advanced non-small-cell lung cancer: A report of the international CATAPULT I study group. Cisplatin and Tirapazamine in Subjects with Advanced Previously Untreated Non-Small-Cell Lung Tumors. (United States)

    von Pawel, J; von Roemeling, R; Gatzemeier, U; Boyer, M; Elisson, L O; Clark, P; Talbot, D; Rey, A; Butler, T W; Hirsh, V; Olver, I; Bergman, B; Ayoub, J; Richardson, G; Dunlop, D; Arcenas, A; Vescio, R; Viallet, J; Treat, J


    A phase III trial, Cisplatin and Tirapazamine in Subjects with Advanced Previously Untreated Non-Small-Cell Lung Tumors (CATAPULT I), was designed to determine the efficacy and safety of tirapazamine plus cisplatin for the treatment of non-small-cell lung cancer (NSCLC). Patients with previously untreated NSCLC were randomized to receive either tirapazamine (390 mg/m(2) infused over 2 hours) followed 1 hour later by cisplatin (75 mg/m(2) over 1 hour) or 75 mg/m(2) of cisplatin alone, every 3 weeks for a maximum of eight cycles. A total of 446 patients with NSCLC (17% with stage IIIB disease and pleural effusions; 83% with stage IV disease) were entered onto the study. Karnofsky performance status (KPS) was >/= 60 for all patients (for 10%, KPS = 60; for 90%, KPS = 70 to 100). Sixty patients (14%) had clinically stable brain metastases. The median survival was significantly longer (34.6 v 27. 7 weeks; P =.0078) and the response rate was significantly greater (27.5% v 13.7%; P CATAPULT I study shows that tirapazamine enhances the activity of cisplatin in patients with advanced NSCLC and confirms that hypoxia is an exploitable therapeutic target in human malignancies.

  14. Weak polyelectrolyte complexation driven by associative charging (United States)

    Rathee, Vikramjit S.; Zervoudakis, Aristotle J.; Sidky, Hythem; Sikora, Benjamin J.; Whitmer, Jonathan K.


    Weak polyelectrolytes are relevant for a wide range of fields; in particular, they have been investigated as "smart" materials for chemical separations and drug delivery. The charges on weak polyelectrolytes are dynamic, causing polymer chains to adopt different equilibrium conformations even with relatively small changes to the surrounding environment. Currently, there exists no comprehensive picture of this behavior, particularly where polymer-polymer interactions have the potential to affect charging properties significantly. In this study, we elucidate the novel interplay between weak polyelectrolyte charging and complexation behavior through coupled molecular dynamics and Monte Carlo simulations. Specifically, we investigate a model of two equal-length and oppositely charging polymer chains in an implicit salt solution represented through Debye-Hückel interactions. The charging tendency of each chain, along with the salt concentration, is varied to determine the existence and extent of cooperativity in charging and complexation. Strong cooperation in the charging of these chains is observed at large Debye lengths, corresponding to low salt concentrations, while at lower Debye lengths (higher salt concentrations), the chains behave in apparent isolation. When the electrostatic coupling is long-ranged, we find that a highly charged chain strongly promotes the charging of its partner chain, even if the environment is unfavorable for an isolated version of that partner chain. Evidence of this phenomenon is supported by a drop in the potential energy of the system, which does not occur at the lower Debye lengths where both potential energies and charge fractions converge for all partner chain charging tendencies. The discovery of this cooperation will be helpful in developing "smart" drug delivery mechanisms by allowing for better predictions for the dissociation point of delivery complexes.

  15. Tidal Effects on Groundwater in a Very Small Tropical Island: A Study on the Groundwater Resources of Pag-asa Island, Kalayaan Island Group

    Directory of Open Access Journals (Sweden)

    John Ong


    Full Text Available The Pag-asa Island, with its very small land area and low relief, has a very limited fresh water supply occurring as a thin freshwater lens. Climate, topography, vegetation, lithology, human abstractions, and tides affect the volume of the freshwater lens. Topographic and hydrogeologic surveys, coupled with a 72-hour groundwater-monitoring program were done to assess the effects of tides on the freshwater lens.Groundwater parameters measured in wells during the monitoring program include variations in water table depths, specific electrical conductivity (SEC, and temperature. Changes in these parameters were then correlated with the observed variations of the tides.The groundwater levels oscillate with the tides at varying amplitudes. The hydraulic properties of the lithologies making up the island's aquifer influence the amplitude of the oscillations. Groundwater level oscillations are least in the reef materials and greatest in the sandy materials where it is nearly simultaneous with the tidal variations. High electrical conductivity values are marked in wells built near the coasts and in sandy materials.The average annual precipitation is approximately 2,020 mm. Based on empirical studies, the estimated sustainable yield for small tropical islands is 6% of the lowest annual rainfall or about 20,300 m3/yr for Pag-asa Island.

  16. Effects of electron-withdrawing group and electron-donating core combinations on physical properties and photovoltaic performance in D-pi-A star-shaped small molecules

    NARCIS (Netherlands)

    Luponosov, Yuriy N.; Min, Jie; Solodukhin, Alexander N.; Kozlov, Oleg V.; Obrezkova, Marina A.; Peregudova, Svetlana M.; Ameri, Tayebeh; Chvalun, Sergei N.; Pshenichnikov, Maxim S.; Brabec, Christoph J.; Ponomarenko, Sergei A.

    The first representatives of star-shaped molecules having 3-alkylrhodanine (alkyl-Rh) electron-withdrawing groups, linked through bithiophene pi-spacer with electron-donating either triphenylamine (TPA) or tris(2-methoxyphenyl)amine (m-TPA) core were synthesized. The physical properties and

  17. Designing Cooperative Learning in the Science Classroom: Integrating the Peer Tutoring Small Investigation Group (PTSIG) within the Model of the Six Mirrors of the Classroom Model (United States)

    Lazarowitz, Reuven; Hertz-Lazarowitz, Rachel; Khalil, Mahmood; Ron, Salit


    The model of the six mirrors of the classroom and its use in teaching biology in a cooperative learning mode were implemented in high school classrooms. In this study we present: a) The model of the six mirrors of the classroom (MSMC). b) Cooperative learning settings: 1. The Group Investigation; 2. The Jigsaw Method; and 3. Peer Tutoring in Small…

  18. Do medical students generate sound arguments during small group discussions in problem-based learning?: an analysis of preclinical medical students' argumentation according to a framework of hypothetico-deductive reasoning. (United States)

    Ju, Hyunjung; Choi, Ikseon; Yoon, Bo Young


    Hypothetico-deductive reasoning (HDR) is an essential learning activity and a learning outcome in problem-based learning (PBL). It is important for medical students to engage in the HDR process through argumentation during their small group discussions in PBL. This study aimed to analyze the quality of preclinical medical students' argumentation according to each phase of HDR in PBL. Participants were 15 first-year preclinical students divided into two small groups. A set of three 2-hour discussion sessions from each of the two groups during a 1-week-long PBL unit on the cardiovascular system was audio-recorded. The arguments constructed by the students were analyzed using a coding scheme, which included four types of argumentation (Type 0: incomplete, Type 1: claim only, Type 2: claim with data, and Type 3: claim with data and warrant). The mean frequency of each type of argumentation according to each HDR phase across the two small groups was calculated. During small group discussions, Type 1 arguments were generated most often (frequency=120.5, 43%), whereas the least common were Type 3 arguments (frequency=24.5, 8.7%) among the four types of arguments. The results of this study revealed that the students predominantly made claims without proper justifications; they often omitted data for supporting their claims or did not provide warrants to connect the claims and data. The findings suggest instructional interventions to enhance the quality of medical students' arguments in PBL, including promoting students' comprehension of the structure of argumentation for HDR processes and questioning.

  19. Solvent-resistant small molecule solar cells by roll-to-roll fabrication via introduction of azide cross-linkable group

    DEFF Research Database (Denmark)

    Chen, Mei-Rong; Fan, Cong-Cheng; Andersen, Thomas Rieks


    A novel cross-linkable azide-functionalized diketopyrrolopyrrole based compound DPP(BT-N-3)(2) was designed and synthesized via Stille coupling. Cross-linking of such molecule could help us fabricate insoluble film which could be used to fabricate heterostructures through solution processing......, without dissolving the pre-patterned layers. In order to investigate the photovoltaic performances of the newly synthesized compound, large area solar cells were produced by roll coating technique. Two set of devices were fabricated by employing DPP(BT-N-3)(2) as either an electron donor or acceptor....... A best power conversion efficiency of 0.067%, combined with an open circuit voltage of 0.53 V, and a fill factor of 37.6% were obtained for the device with DPP(BT-N-3)(2) as an electron acceptor. In addition, we could prove that the large area small molecule based organic solar cells could be fabricated...

  20. Contractor Software Charges

    National Research Council Canada - National Science Library

    Granetto, Paul


    .... Examples of computer software costs that contractors charge through indirect rates are material management systems, security systems, labor accounting systems, and computer-aided design and manufacturing...

  1. Charge balancing fill rate monitor

    International Nuclear Information System (INIS)

    Rothman, J.L.; Blum, E.B.


    A fill rate monitor has been developed for the NSLS storage rings to allow machine tuning over a very large dynamic range of beam current. Synchrotron light, focused on a photodiode, produces a signal proportional to the beam current. A charge balancing circuit processes the diode current, creating an output signal proportional to the current injected into the ring. The unit operates linearly over a dynamic range of 120 dB and can resolve pulses of injected beam as small as 1 μA

  2. Feasibility study of docetaxel plus bevacizumab as first line therapy for elderly patients with advanced non-small-cell lung cancer: Thoracic Oncology Research Group (TORG) 1014

    International Nuclear Information System (INIS)

    Takagi, Yusuke; Hosomi, Yukio; Oshita, Fumihiro; Okamoto, Hiroaki; Seki, Nobuhiko; Minato, Koichi; Aono, Hiromi; Yamada, Kouzo; Okuma, Yusuke; Hida, Naoya; Sakamoto, Takahiko; Miura, Yosuke; Yomota, Makiko; Satoh, Akira; Kunitoh, Hideo; Sakamaki, Kentaro; Shibuya, Masahiko; Watanabe, Koshiro


    Docetaxel monotherapy is one of the standard treatments for non-small-cell lung cancer in elderly patients. The addition of bevacizumab to docetaxel seems promising; however, the feasibility of this combination has not been investigated in such patients. Patients with advanced non-squamous non-small-cell lung cancer aged 70 years or older who had not previously received cytotoxic chemotherapy were enrolled. Patients in the Level 0 cohort received docetaxel 60 mg/m 2 and bevacizumab 15 mg/kg, whereas those in the Level-1 cohort received docetaxel 50 mg/m 2 and bevacizumab 15 mg/kg. Chemotherapy was repeated 3 weekly for six cycles. The primary endpoint was toxicity and the secondary endpoints were response rate, progression-free survival, overall survival, and proportion of patients who underwent three or more cycles of chemotherapy. Twenty-one patients were enrolled from December 2010 to September 2012 at six institutes. Of the nine patients enrolled in Level 0, two experienced dose-limiting toxicity (febrile neutropenia and prolonged Grade 4 neutropenia in one patient, and Grade 3 infection in another patient) during the first cycle. Enrollment to the Level 0 cohort was terminated because two patients developed Grade 4 sepsis during later cycles. The remaining 12 patients were enrolled in the Level-1 cohort, in which two dose-limiting toxicities (prolonged Grade 4 neutropenia and Grade 3 increased aminotransferase level) were observed. No patient in the Level-1 cohort experienced Grade 4 nonhematologic toxicity. Grade 4 neutropenia occurred in 89 % of Level 0 patients and 50 % of Level-1 patients. The proportion of patients who experienced Grade 3/4 infection, febrile neutropenia or sepsis was 44 % in the Level 0 cohort, and 8 % in the Level-1 cohort. The overall response rate to chemotherapy and progression-free survival were 29 % (95 % CI, 11–52 %) and 5.9 months (95 % CI, 3.6–9.1 months), respectively. Efficacy outcomes did not differ significantly between

  3. Clustering of continuous distributions of charge (United States)

    Heyes, D. M.; Rickayzen, G.


    An investigation is carried out of the association and clustering of equimolar mixtures of oppositely charged Gaussian charge distributions (CDs) of the form ∼ exp ( - r2 /2α2), where r is the separation between the centres of charge and α governs the extent of charge spreading (α→0 is the point charge limit). The results of molecular dynamics (MD) and Ornstein-Zernike integral equation with the mean spherical approximation (MSA) and hypernetted-chain (HNC) closures are compared for these systems. The MD and HNC radial distribution functions, g(r), agree very well for not too small α. The MD and MSA, g(r), also agree well for α ≈ 1 and greater. The potential energy per particle for the three methods also agrees well over a wider range of α values, better than might be expected from inspection of the radial distribution functions, because the dominant contributions to U come predominantly from intermediate and long distance ranges where there is good agreement between the g(r) from the MSD and HNC closures. The nature of the association and clustering of the charges as a function of α is explored through the mean nearest neighbour distance for unlike and like species and the mean and root-mean-square force. The velocity and force autocorrelation functions are also calculated; they show increasingly oscillatory behaviour in the small α limit, originating in vibrations of a pair of CDs of opposite sign.

  4. Charge Screening in a Charged Condensate

    International Nuclear Information System (INIS)

    Gabadadze, Gregory; Rosen, Rachel A.


    We consider a highly dense system of helium-4 nuclei and electrons in which the helium-4 nuclei have condensed. We present the condensation mechanism in the framework of low energy effective field theory and discuss the screening of electric charge in the condensate.

  5. Surface Charging and Points of Zero Charge

    CERN Document Server

    Kosmulski, Marek


    Presents Points of Zero Charge data on well-defined specimen of materials sorted by trademark, manufacturer, and location. This text emphasizes the comparison between particular results obtained for different portions of the same or very similar material and synthesizes the information published in research reports over the past few decades

  6. The importance of aquaculture community group (ACG) in social media (Facebook) towards the aquaculture knowledge and financial improvement of small scale fish farmers (SSFF) in rural areas of Central Java (United States)

    Elfitasari, T.; Nugroho, R. A.; Nugroho, A. P.


    Internet is now widely used by people all over the world, including small scale fisheries communities such as fish farmers. Many applications are being created including social media Facebook which are used by small scale fish farmers (SSFF) for its ease and convenience. The objective of this research is to identify the impact of aquaculture community group (ACG) in social media Facebook towards the improvement of aquaculture knowledge and financial condition of small scale fish farmers in Central Java. This research used quantitative approach where questionnaires were distributed into two groups: SSFF who are member of ACG in social media Facebook and who are not. Sampling technique used random sampling, used 60 samples of SSFF in Central Java. Data obtained were tested using the test statistic Independent t-test using SPSS v.20. Result showed a significant effect of group who are member of ACG in social media Facebook and those who are not, towards the aquaculture knowledge (t count -7.424 and sig 0.000) and financial improvement (t -3.775 and sig 0.000). The results of the average value of the SSFF who are ACG member in Facebook are also higher than farmers who are not.

  7. Total half-body systemic irradiation for occult metastases in non-small cell lung cancer: an Eastern Cooperative Oncology group pilot report

    International Nuclear Information System (INIS)

    Salazar, O.M.; Scarantino, C.W.; Rubin, P.; Feldstein, M.L.; Keller, B.E.


    There is a high probability for patients with locally advanced, unresectable, nonmetastatic, nonsmall-cell bronchogenic carcinoma (NSCBC) to harbor subclinical distant metastases at diagnosis. Approximately 30% will disseminate in the first three months and an additional 50% will disseminate before a year has elapsed. Twenty advanced nonmetastatic patients wtith NSCBC were treated with localized split-course chest irradiation (LCI) plus total body (upper and lower half-body) irradiation for occult metastases. Thirty equally advanced, nonmetastatic patients, who were treated with only localized split-course chest irradiation, were matched and served as a retrospective control group. Apparently, the median recurrence free survival, metastatic free interval, and median survival were significantly prolonged, and there was a decrease in the incidence of liver metastases in patients receiving HBI for occult metastases over the patients of the control group. Although elective HBI seems to delay the appearance of distant metastases, it did not prevent their occurrence, alter patterns of first relapse, or significantly improve the overall survival. Nevertheless, a therapeutic gain may have been achieved and is discussed. The incidence of radiation pneumonitis with 800 rad of UHBI corrected for lung transmission was 9%. A hypothesis and a rationale for a more effective combined modality therapy in these patients is given

  8. Unilateral CHARGE association

    NARCIS (Netherlands)

    Trip, J; van Stuijvenberg, M; Dikkers, FG; Pijnenburg, MWH

    A case with a predominantly unilateral CHARGE association is reported. The CHARGE association refers to a combination of congenital malformations. This boy had left-sided anomalies consisting of choanal atresia. coloboma and peripheral facial palsy. The infant had a frontal encephalocele. an anomaly

  9. Failure patterns by prognostic group as determined by recursive partitioning analysis (RPA) of 1547 on four radiation therapy oncology group studies in operable non-small cell lung cancer (NSCLC)

    International Nuclear Information System (INIS)

    Komaki, Ritsuko; Scott, Charles B.; Byhardt, Roger W.; Emami, Bahman; Asbell, Sucha O.; Russell, Anthony H.; Roach, Mack; Urtasun, Raul C.; Gaspar, Laurie E.


    Purpose: To identify groups of patients who might benefit from more aggressive systemic or local treatment based on failure patterns when unresectable NSCLC was treated by radiation therapy alone. Methods: 1547 patients from 4 RTOG trials treated by RT alone were analyzed for the patterns of first failure by PRA class which was defined by prognostic factors, e.g., stage, KPS, weight loss, pleural effusion, age. All patients were AJCC stage II, IIIA or IIIB with KPS of at least 50 and n previous radiotherapy or chemotherapy for their NSCLC. Progressions in the primary (within irradiated fields), thorax (outside irradiated area), brain and distant metastasis other than brain were compared (two-sided) for each failure category by RPA. Results: The RPA classes are four distinct subgroups that had significantly different median survivals of 12.6, 8.3, 6.2 and 3.3 months for classes I, II, III and IV respectively (all groups p=0.0002). Pair comparison showed that RPA I vs IV p<0.0001, I vs III p=0.006, II vs IV p<0.0001, and III vs IV p=0.06. Conclusions: These results suggest the burden of disease and physiologic compromise in class IV patients are sufficient to cause death before specific sites of failure can be discerned. Site specific treatment strategies (intensive local therapy, combination chemotherapy, prophylactic cranial irradiation) may lead to improved outcome in class I and II, but are unlikely to alter outcome in class III and IV

  10. Atum: Scalable Group Communication Using Volatile Groups


    Guerraoui, Rachid; Kermarrec, Anne-Marie; Pavlovic, Matej; Seredinschi, Dragos-Adrian


    This paper presents Atum, a group communication middleware for a large, dynamic, and hostile environment. At the heart of Atum lies the novel concept of volatile groups: small, dynamic groups of nodes, each executing a state machine replication protocol, organized in a flexible overlay. Using volatile groups, Atum scatters faulty nodes evenly among groups, and then masks each individual fault inside its group. To broadcast messages among volatile groups, Atum runs a gossip protocol across the...

  11. Electrical charging of skis gliding on snow. (United States)

    Colbeck, S C


    Ski charging was measured using giant-slalom style skis as gliding capacitors. The voltage measured across the plates was proportional to the charge on the base. While resting on dry snow or suspended in the air, the voltage was slowly reduced by the data logger itself. On wet snow the decay was much faster. While stationary on powder snow the ski developed a slightly negative voltage, showed a small, transient positive peak when motion began, rapidly dropped to negative values, and then assumed a quasi-steady climb to positive voltages. A great deal of noise was superimposed on the general features of the signal when skiing on hard or bumpy surfaces. Thus, the accumulation of charge to high levels was only possible with long runs in deep powder. The rate of charging increased with speed but was not affected by use of one "antistatic" wax, and another such wax actually increased the measured voltage over that of an unwaxed base.

  12. Mean xenograft survival of 14.6 days in a small group of hDAF-transgenic pig hearts transplanted orthotopically into baboons. (United States)

    Brenner, P; Schmoeckel, M; Wimmer, C; Eder, V; Rucker, A; Felbinger, T; Uchita, S; Hinz, M; Brandl, U; Meiser, B; Reichenspurner, H; Hammer, C; Reichart, B


    In a discordant orthotopic xenotransplantation model (pig-to-baboon) donor pigs expressing human decay accelerating factor (hDAF) as a regulator of complement activity were used to prevent hyperacute xenograft rejection (HXR). We investigated a modified immunosuppressive therapy consisting of ERL080 (Novartis Pharma AG, Base, Switzerland), cyclosporin A (Neoral), steroids, and a cyclophosphamide (CyP) induction protocol with several reduced doses to prevent acute vascular rejection (AVR). Donor hearts were harvested from hDAF-transgenic pigs (18.8 +/- 2.6 kg, Imutran Ltd., a Novartis Pharma AG Company). Four adult baboons (25.6 +/- 2.7 kg) with high titers of xenoreactive antibodies (XAb) served as recipients. Serological and hemodynamic parameters were measured. Finally, myocardial tissue was sampled for histological and immunohistochemical examinations. In the first baboon, an acute graft failure occurred after 1 hour due to preservation injury. The second succumbed after 11.1 day due to an acute renal failure. The third died after 13.1 days of an ileus. The fourth baboon had continuously excellent cardiac function (mean echocardiographic ejection fraction, 69.2%), but succumbed on day 20 due to anemia. Corrected mean xenograft survival (excluding the first baboon because of a technical failure) was 14.6 +/- 2.6 days. XAb decreased after day 3 to constantly low levels (transgen blocks HXR in this life-supporting model. AVR was prevented by using a modified quadruple immunosuppressive drug combination (Neoral, ERL080, steroids, and several small single doses of CyP). An optimum "fine-tuning" of immunosuppression is required to achieve the best risk-benefit ratio.

  13. Gemcitabine plus docetaxel as first-line chemotherapy in patients with advanced non-small cell lung cancer: a lung cancer Galician group phase II study. (United States)

    Casal, Joaquín; Amenedo, Margarita; Mel, José Ramón; Antón, Luis Miguel; Rodríguez-López, Rubén; López-López, Rafael; González-Ageitos, Ana; Castellanos, Javier; Constenla, Manuel; Tisaire, José L


    Numerous phase II and III clinical trials have demonstrated a higher activity of combined gemcitabine plus docetaxel schedules against non-small cell lung cancer (NSCLC) than that of both agents in monotherapy. This phase II study evaluated a 3-week based schedule of docetaxel 85 mg/m(2) (1-h i.v. infusion, d8) combined with gemcitabine 1,000 mg/m(2) (30-min i.v. infusion; d1,8) as first-line chemotherapy for patients with advanced NSCLC. Forty-one patients with non-resectable, stage IIIB/IV, and bidimensionally measurable disease were enrolled. A total of 182 chemotherapy cycles (median 6, range 1-6) was administered to 40 patients during the study; one patient did not receive chemotherapy due to a protocol deviation. Two patients were not evaluable for treatment efficacy. The overall response rate found was 44% (95% CI, 29-59%): three patients (7%) had a complete response and 15 patients (37%) had a partial response (median duration of response = 4.0 months). With a median follow-up of 8.7 months, the median time to disease progression was 4.4 months and the median overall survival was 7.3 months. The combined gemcitabine plus docetaxel chemotherapy was well tolerated except for pulmonary toxicity. The main grade 3-4 hematological toxicity was neutropenia (28% of patients, 9% of cycles). Two cases of febrile neutropenia were reported. The main grade 3-4 non-hematological toxicity was pulmonary toxicity (23% of patients, 6% of cycles). Gemcitabine 1,000 mg/m(2) on days 1 and 8 in combination with docetaxel 85 mg/m(2) on day 8 given in 3-week cycles is an active and well-tolerated first-line chemotherapeutic regimen for advanced NSCLC.

  14. Within-Case and Cross-Case Analyses of Questions Posed by Fifth-Grade Students Working in Small Groups to Investigate Pendulum Motion (United States)

    Tisel, James Michael

    The focus of this basic qualitative research is student questions in an unstructured inquiry setting. Case and cross-case analyses were conducted (Miles and Huberman, 1984) of the questions posed by fifth grade students working in laboratory groups of size three to five students as they investigated pendulum motion. To establish the conceptual framework for the study, literature was reviewed in the areas of cognitive theory (constructivism, conceptual change, and other theories), approaches to science, and the importance of student questions in the learning process. A review of group work, related studies of student questions and activities and relevant methods of qualitative research was also undertaken. The current study occupies the relatively unique position of being about the questions students posed to each other (not the teacher) at the outset of and throughout an unstructured inquiry activity with a minimum of teacher initiation or intervention. The focus is on finding out what questions students ask, when they ask them, what categories the questions fall into in relation to possible models of the scientific method, student motivation, and what role the questions play as the students take part in an inquiry activity. Students were video and/or audio-recorded as they did the investigation. They wrote down their questions during one-minute pauses that occurred at roughly eight-minute intervals. The groups were interviewed the next day about their experience. The recordings, question sheets, and interview accounts and recordings were analyzed by the researcher. Accounts of the experience of each group were prepared, and reiterated attempts were made to classify the questions as the main themes and categories emerged. It was found that students posed their key research question (most typically related to pendulum damping effects) midway through the first half of their activity, after having first met some competence and other needs in relation to measurement

  15. Charge transfer in TATB and HMX under extreme conditions. (United States)

    Zhang, Chaoyang; Ma, Yu; Jiang, Daojian


    Charge transfer is usually accompanied by structural changes in materials under different conditions. However, the charge transfer in energetic materials that are subjected to extreme conditions has seldom been explored by researchers. In the work described here, the charge transfer in single molecules and unit cells of the explosives TATB and HMX under high temperatures and high pressures was investigated by performing static and dynamic calculations using three DFT methods, including the PWC functional of LDA, and the BLYP and PBE functionals of GGA. The results showed that negative charge is transferred from the nitro groups of molecular or crystalline TATB and HMX when they are heated. All DFT calculations for the compressed TATB unit cell indicate that, generally, negative charge transfer occurs to its nitro groups as the compression increases. PWC and PBE calculations for crystalline HMX show that negative charge is first transferred to the nitro groups but, as the compression increases, the negative charge is transferred from the nitro groups. However, the BLYP calculations indicated that there was gradual negative charge transfer to the nitro groups of HMX, similar to the case for TATB. The unrelaxed state of the uniformly compressed TATB causes negative charge to be transferred from its nitro groups, in contrast to what is seen in the relaxed state. Charge transfer in TATB is predicted to occur much more easily than in HMX.

  16. Gemcitabine plus best supportive care (BSC) vs BSC in inoperable non-small cell lung cancer--a randomized trial with quality of life as the primary outcome. UK NSCLC Gemcitabine Group. Non-Small Cell Lung Cancer. (United States)

    Anderson, H; Hopwood, P; Stephens, R J; Thatcher, N; Cottier, B; Nicholson, M; Milroy, R; Maughan, T S; Falk, S J; Bond, M G; Burt, P A; Connolly, C K; McIllmurray, M B; Carmichael, J


    Three hundred patients with symptomatic, locally advanced or metastatic NSCLC not requiring immediate radiotherapy were enrolled into this randomized multicentre trial comparing gemcitabine + BSC vs BSC alone. Patients allocated gemcitabine received 1000 mg/m2 on days 1, 8 and 15 of a 28-day cycle, for a maximum of six cycles. The main aim of this trial was to compare patient assessment of a predefined subset of commonly reported symptoms (SS14) from the EORTC QLQ-C30 and LC13 scales. The primary end-points were defined as (1) the percentage change in mean SS14 score between baseline and 2 months and (2) the proportion of patients with a marked (> or = 25%) improvement in SS14 score between baseline and 2 months sustained for > or =4 weeks. The secondary objectives were to compare treatments with respect to overall survival, and multidimensional QL parameters. The treatment groups were balanced with regard to age, gender, Karnofsky performance status (KPS) and disease stage (40% had metastatic disease). The percentage change in mean SS14 score from baseline to 2 months was a 10% decrease (i.e. improvement) for gemcitabine plus BSC and a 1% increase (i.e. deterioration) for BSC alone (P = 0.113, two-sample t-test). A sustained (> or = 4 weeks) improvement (> or =25%) on SS14 was recorded in a significantly higher proportion of gemcitabine + BSC patients (22%) than in BSC alone patients (9%) (P = 0.0014, Pearson's chi-squared test). The QLQ-C30 and L13 subscales showed greater improvement in the gemcitabine plus BSC arm (in 11 domains) than in the BSC arm (one symptom item). There was greater deterioration in the BSC alone arm (six domains/items) than in the gemcitabine + BSC arm (three QL domains). Tumour response occurred in 19% (95% CI 13-27) of gemcitabine patients. There was no difference in overall survival: median 5.7 months (95% CI 4.6-7.6) for gemcitabine + BSC patients and 5.9 months (95% CI 5.0-7.9) (log-rank, P = 0.84) for BSC patients, and 1 -year

  17. Charge-transport simulations in organic semiconductors

    Energy Technology Data Exchange (ETDEWEB)

    May, Falk


    In this thesis we have extended the methods for microscopic charge-transport simulations for organic semiconductors, where weak intermolecular interactions lead to spatially localized charge carriers, and the charge transport occurs as an activated hopping process between diabatic states. In addition to weak electronic couplings between these states, different electrostatic environments in the organic material lead to a broadening of the density of states for the charge energies which limits carrier mobilities. The contributions to the method development include (i) the derivation of a bimolecular charge-transfer rate, (ii) the efficient evaluation of intermolecular (outer-sphere) reorganization energies, (iii) the investigation of effects of conformational disorder on intramolecular reorganization energies or internal site energies and (iv) the inclusion of self-consistent polarization interactions for calculation of charge energies. These methods were applied to study charge transport in amorphous phases of small molecules used in the emission layer of organic light emitting diodes (OLED). When bulky substituents are attached to an aromatic core in order to adjust energy levels or prevent crystallization, a small amount of delocalization of the frontier orbital to the substituents can increase electronic couplings between neighboring molecules. This leads to improved charge-transfer rates and, hence, larger charge-mobility. We therefore suggest using the mesomeric effect (as opposed to the inductive effect) when attaching substituents to aromatic cores, which is necessary for example in deep blue OLEDs, where the energy levels of a host molecule have to be adjusted to those of the emitter. Furthermore, the energy landscape for charges in an amorphous phase cannot be predicted by mesoscopic models because they approximate the realistic morphology by a lattice and represent molecular charge distributions in a multipole expansion. The microscopic approach shows that

  18. Charge Storage, Conductivity and Charge Profiles of Insulators As Related to Spacecraft Charging


    Dennison, JR; Frederickson, A. R.; Swaminathan, Prasanna


    Dissipation of charges built up near the surface of insulators due to space environment interaction is central to understanding spacecraft charging. Conductivity of insulating materials is key to determine how accumulated charge will distribute across the spacecraft and how rapidly charge imbalance will dissipate. To understand these processes requires knowledge of how charge is deposited within the insulator, the mechanisms for charge trapping and charge transport within the insulator, and h...

  19. Charge transport in organic crystals

    Energy Technology Data Exchange (ETDEWEB)

    Ortmann, Frank


    The understanding of charge transport is one of the central goals in the research on semiconducting crystals. For organic crystals this is particularly complicated due to the strength of the electron-phonon interaction which requires the description of a seamless transition between the limiting cases of a coherent band-transport mechanism and incoherent hopping. In this thesis, charge transport phenomena in organic crystals are studied by theoretical means. A theory for charge transport in organic crystals is developed which covers the whole temperature range from low T, where it reproduces an expression from the Boltzmann equation for band transport, via elevated T, where it generalizes Holstein's small-polaron theory to finite bandwidths, up to high T, for which a temperature dependence equal to Marcus' electron-transfer theory is obtained. Thereby, coherent band transport and thermally induced hopping are treated on equal footing while simultaneously treating the electron-phonon interaction non-perturbatively. By avoiding the approximation of narrow polaron bands the theory allows for the description of large and small polarons and serves as a starting point for computational studies. The theoretical description is completed by using ab initio material parameters for the selected crystals under study. These material parameters are taken from density functional theory calculations for durene, naphthalene, and guanine crystals. Besides the analysis of the transport mechanism, special focus is put on the study of the relationship between mobility anisotropy and structure of the crystals. This study is supported by a 3D-visualization method for the transport channels in such crystals which has been derived in this thesis. (orig.)

  20. Self-excitation of space charge waves

    DEFF Research Database (Denmark)

    Lyuksyutov, Sergei; Buchhave, Preben; Vasnetsov, Mikhail


    We report a direct observation of space charge waves in photorefractive crystals with point group 23 (sillenites) based on their penetration into an area with uniform light illumination. It is shown experimentally that the quality factor of the waves increases substantially with respect to what...... current theory predicts [B. Sturman el al., Appl. Phys. A 55, 235 (1992)]. This results in the appearance of strong spontaneous beams caused by space charge wave self-excitation....

  1. Role of protein surface charge in monellin sweetness. (United States)

    Xue, Wei-Feng; Szczepankiewicz, Olga; Thulin, Eva; Linse, Sara; Carey, Jannette


    A small number of proteins have the unusual property of tasting intensely sweet. Despite many studies aimed at identifying their sweet taste determinants, the molecular basis of protein sweetness is not fully understood. Recent mutational studies of monellin have implicated positively charged residues in sweetness. In the present work, the effect of overall net charge was investigated using the complementary approach of negative charge alterations. Multiple substitutions of Asp/Asn and Glu/Gln residues radically altered the surface charge of single-chain monellin by removing six negative charges or adding four negative charges. Biophysical characterization using circular dichroism, fluorescence, and two-dimensional NMR demonstrates that the native fold of monellin is preserved in the variant proteins under physiological solution conditions although their stability toward chemical denaturation is altered. A human taste test was employed to determine the sweetness detection threshold of the variants. Removal of negative charges preserves monellin sweetness, whereas added negative charge has a large negative impact on sweetness. Meta-analysis of published charge variants of monellin and other sweet proteins reveals a general trend toward increasing sweetness with increasing positive net charge. Structural mapping of monellin variants identifies a hydrophobic surface predicted to face the receptor where introduced positive or negative charge reduces sweetness, and a polar surface where charges modulate long-range electrostatic complementarity.

  2. Charge gradient microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Roelofs, Andreas; Hong, Seungbum


    A method for rapid imaging of a material specimen includes positioning a tip to contact the material specimen, and applying a force to a surface of the material specimen via the tip. In addition, the method includes moving the tip across the surface of the material specimen while removing electrical charge therefrom, generating a signal produced by contact between the tip and the surface, and detecting, based on the data, the removed electrical charge induced through the tip during movement of the tip across the surface. The method further includes measuring the detected electrical charge.

  3. Isoindigo-based small molecules for high-performance solution-processed organic photovoltaic devices: the electron donating effect of the donor group on photo-physical properties and device performance. (United States)

    Elsawy, Walaa; Lee, Chang-Lyoul; Cho, Shinuk; Oh, Seung-Hwan; Moon, Seung-Hyeon; Elbarbary, Ahmed; Lee, Jae-Suk


    Five solution processable isoindigo-based donor-acceptor-donor (D-A-D) small molecules with different electron donating strengths have been designed and synthesized. The variation in the electron donating strength of the donor group strongly affected the optical, thermal, electrochemical and photovoltaic device performances of the isoindigo organic materials. The highest power conversion efficiency of ~3.2% was achieved in the bulk heterojunction photovoltaic device consisting of ID3T as the donor and PC70BM as the acceptor. This work demonstrates the potential of isoindigo moieties as electron-deficient units and presents guidelines for the synthesis of D-A-D small molecules for producing highly efficient, solution-processed organic photovoltaic devices.

  4. Factors which influence quality of life in patients with non-small cell lung cancer (NSCLC): A radiation therapy oncology group study (RTOG 89-01)

    International Nuclear Information System (INIS)

    Scott, C.B.; Sause, W.T.; Johnson, D.; Dar, A.R.; Wasserman, T.H.; Rubin, P.; Khandekar, J.; Byhardt, R.B.; Taylor, S.; McDonald, A.


    Purpose: Prospectively evaluate the quality of life (QOL) of patients with NSCLC participating in a randomized phase III study conducted by the RTOG and Eastern Cooperative Oncology Group. Determine the factors which influence QOL during and post therapy. Materials and Methods: From (4(90)) to (4(94)) to 75 patients (pts) were randomized on RTOG 89-01 between a regimen containing radiation therapy (RT) versus a regimen containing surgery (S). All pts received induction vinblastine and cisplatin, followed by either S or RT and consolidation chemotherapy (CT). Pts were given the self-assessment QOL forms prior to the start of therapy, post induction CT, post RT or S, and periodically during follow-up. Two questionnaires were used: Functional Assessment of Cancer Therapy for lung cancer patients (FACT-L) and Functional Living Index-Cancer (FLIC). The FACT-L consists of 44 questions covering 6 domains (physical, social, and emotional well-being, relationship with physician, fulfilment, and lung cancer specific concerns), FLIC contains 22 questions summing to one total score. Results: 51 pts participated in the QOL endpoint, 24 were excluded: 3 pts refused, institution did not administer QOL questionnaires in 9 pts, 3 completed QOL after start of therapy, 1 institution refused to participate, 5 questionnaires were incomplete/unusable, 1 pt could not read English, and 2 were ineligible for treatment. Participation in QOL was not predicted by any pretreatment characteristic. Women had worse pretreatment QOL (p<0.005, by FLIC) and more problems with disease-related symptoms (p<0.005, by FACT) than men. Pts with KPS 90-100 had better pretreatment QOL than pts with KPS 60-80 (p<0.025, FLIC). Neither race, marital status, education level, age, prior weight loss, nor disease symptoms statistically significantly influenced pretreatment QOL. Initial QOL did not predict overall survival. FACT-L was reported on 25 pts post induction CT. Follow-up FACT-L was available on 12 pts

  5. Counterion Condensation and Effective Charge of PAMAM Dendrimers

    Directory of Open Access Journals (Sweden)

    Ulrich Scheler


    Full Text Available PAMAM dendrimers are used as a model system to investigate the effects of counterion condensation and the effective charge for spherical polyelectrolytes. Because of their amino groups, PAMAM dendrimers are weak polyelectrolytes. Lowering the pH results in an increasing protonation of the amino groups which is monitored via the proton chemical shifts of the adjacent CH2 groups. The effective charge is determined from a combination of diffusion and electrophoresis NMR. The fraction of the charges, which are effective for the interaction with an external electric field or other charges, decreases with increasing generation (size of the dendrimers.

  6. The evaporation of the charged and uncharged water drops ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    Oscillations of the drop and the change in airflow around drops are suggested to contribute to lowering of the ventilation coefficients for charged drops. Applicability of the results to a small fraction of highly charged raindrops falling through the sub-cloud layer below thunderstorm is discussed. The relaxation time required for ...

  7. Water Quality Protection Charges (United States)

    Montgomery County of Maryland — The Water Quality Protection Charge (WQPC) is a line item on your property tax bill. WQPC funds many of the County's clean water initiatives including: • Restoration...

  8. Space-Charge Effect

    CERN Document Server

    Chauvin, N.


    First, this chapter introduces the expressions for the electric and magnetic space-charge internal fields and forces induced by high-intensity beams. Then, the root-mean-square equation with space charge is derived and discussed. In the third section, the one-dimensional Child-Langmuir law, which gives the maximum current density that can be extracted from an ion source, is exposed. Space-charge compensation can occur in the low-energy beam transport lines (located after the ion source). This phenomenon, which counteracts the spacecharge defocusing effect, is explained and its main parameters are presented. The fifth section presents an overview of the principal methods to perform beam dynamics numerical simulations. An example of a particles-in-cells code, SolMaxP, which takes into account space-charge compensation, is given. Finally, beam dynamics simulation results obtained with this code in the case of the IFMIF injector are presented.

  9. Electric charge quantization

    International Nuclear Information System (INIS)

    Foot, R.; Lew, H.; Volkas, R.R.


    Experimentally it has been known for a long time that the electric charges of the observed particles appear to be quantized. An approach to understanding electric charge quantization that can be used for gauge theories with explicit U(1) factors - such as the standard model and its variants - is pedagogically reviewed and discussed in this article. This approach used the allowed invariances of the Lagrangian and their associated anomaly cancellation equations. It is demonstrated that charge may be de-quantized in the three-generation standard model with massless neutrinos, because differences in family-lepton-numbers are anomaly-free. The relevant experimental limits are also reviewed. This approach to charge quantization suggests that the minimal standard model should be extended so that family-lepton-number differences are explicitly broken. Some candidate extensions such as the minimal standard model augmented by Majorana right-handed neutrinos are also briefly discussed. 30 refs

  10. EV Charging Infrastructure Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Karner, Donald [Electric Transportation Inc., Rogers, AR (United States); Garetson, Thomas [Electric Transportation Inc., Rogers, AR (United States); Francfort, Jim [Idaho National Lab. (INL), Idaho Falls, ID (United States)


    As highlighted in the U.S. Department of Energy’s EV Everywhere Grand Challenge, vehicle technology is advancing toward an objective to “… produce plug-in electric vehicles that are as affordable and convenient for the average American family as today’s gasoline-powered vehicles …” [1] by developing more efficient drivetrains, greater battery energy storage per dollar, and lighter-weight vehicle components and construction. With this technology advancement and improved vehicle performance, the objective for charging infrastructure is to promote vehicle adoption and maximize the number of electric miles driven. The EV Everywhere Charging Infrastructure Roadmap (hereafter referred to as Roadmap) looks forward and assumes that the technical challenges and vehicle performance improvements set forth in the EV Everywhere Grand Challenge will be met. The Roadmap identifies and prioritizes deployment of charging infrastructure in support of this charging infrastructure objective for the EV Everywhere Grand Challenge

  11. Electric Vehicle Charging Modeling


    Grahn, Pia


    With an electrified passenger transportation fleet, carbon dioxide emissions could be reduced significantly depending on the electric power production mix. Increased electric power consumption due to electric vehicle charging demands of electric vehicle fleets may be met by increased amount of renewable power production in the electrical systems. With electric vehicle fleets in the transportation system there is a need for establishing an electric vehicle charging infrastructure that distribu...

  12. Quadrupole electromagnetic radiation of an oscillating charged droplet (United States)

    Grigor'ev, A. I.; Kolbneva, N. Yu.; Shiryaeva, S. O.


    Analytical calculations using the first order of smallness with respect to dimensionless amplitude of oscillations show that the intensity of electromagnetic radiation of a charged droplet is determined by time-dependent quadrupole moment.

  13. Partial Atomic Charges and Screened Charge Models of the Electrostatic Potential. (United States)

    Wang, Bo; Truhlar, Donald G


    We propose a new screened charge method for calculating partial atomic charges in molecules by electrostatic potential (ESP) fitting. The model, called full density screening (FDS), is used to approximate the screening effect of full charge densities of atoms in molecules. The results are compared to the conventional ESP fitting method based on point charges and to our previously proposed outer density screening (ODS) method, in which the parameters are reoptimized for the present purpose. In ODS, the charge density of an atom is represented by the sum of a point charge and a smeared negative charge distributed in a Slater-type orbital (STO). In FDS, the charge density of an atom is taken to be the sum of the charge density of the neutral atom and a partial atomic charge (of either sign) distributed in an STO. The ζ values of the STOs used in these two models are optimized in the present study to best reproduce the electrostatic potentials. The quality of the fit to the electrostatics is improved in the screened charge methods, especially for the regions that are within one van der Waals radius of the centers of atoms. It is also found that the charges derived by fitting electrostatic potentials with screened charges are less sensitive to the positions of the fitting points than are those derived with conventional electrostatic fitting. Moreover, we found that the electrostatic-potential-fitted (ESP) charges from the screened charge methods are similar to those from the point-charge method except for molecules containing the methyl group, where we have explored the use of restraints on nonpolar H atoms. We recommend the FDS model if the only goal is ESP fitting to obtain partial atomic charges or a fit to the ESP field. However, the ODS model is more accurate for electronic embedding in combined quantum mechanical and molecular mechanical (QM/MM) modeling and is more accurate than point-charge models for ESP fitting, and it is recommended for applications

  14. Search milli-charged particles at SLAC

    Energy Technology Data Exchange (ETDEWEB)

    Langeveld, W.G.J. [Stanford Univ., CA (United States)


    Particles with electric charge q {triple_bond} Qe {le} 10{sup -3} e and masses in the range 1-1000 MeV/c{sup 2} are not excluded by present experiments or by astrophysical or cosmological arguments. A beam dump experiment uniquely suited to the detection of such {open_quotes}milli-charged{close_quotes} particles has been carried out at SLAC, utilizing the short-duration pulses of the SLC electron beam to establish a tight coincidence window for the signal. The detector, a large scintillation counter sensitive to very small energy depositions, provided much greater sensitivity than previous searches. Analysis of the data leads to the exclusion of a substantial portion of the charge-mass plane. In this report, a preliminary mass-dependent upper limit is presented for the charge of milli-charged particles, ranging from Q = 1.7 x 10{sup -5} at milli-charged particle mass 0.1 MeV/c{sup 2} to Q = 9.5 x 10{sup -4} at 100 MeV/c{sup 2}.

  15. Parsimonious Charge Deconvolution for Native Mass Spectrometry (United States)


    Charge deconvolution infers the mass from mass over charge (m/z) measurements in electrospray ionization mass spectra. When applied over a wide input m/z or broad target mass range, charge-deconvolution algorithms can produce artifacts, such as false masses at one-half or one-third of the correct mass. Indeed, a maximum entropy term in the objective function of MaxEnt, the most commonly used charge deconvolution algorithm, favors a deconvolved spectrum with many peaks over one with fewer peaks. Here we describe a new “parsimonious” charge deconvolution algorithm that produces fewer artifacts. The algorithm is especially well-suited to high-resolution native mass spectrometry of intact glycoproteins and protein complexes. Deconvolution of native mass spectra poses special challenges due to salt and small molecule adducts, multimers, wide mass ranges, and fewer and lower charge states. We demonstrate the performance of the new deconvolution algorithm on a range of samples. On the heavily glycosylated plasma properdin glycoprotein, the new algorithm could deconvolve monomer and dimer simultaneously and, when focused on the m/z range of the monomer, gave accurate and interpretable masses for glycoforms that had previously been analyzed manually using m/z peaks rather than deconvolved masses. On therapeutic antibodies, the new algorithm facilitated the analysis of extensions, truncations, and Fab glycosylation. The algorithm facilitates the use of native mass spectrometry for the qualitative and quantitative analysis of protein and protein assemblies. PMID:29376659

  16. Screening effect on nanostructure of charged gel

    DEFF Research Database (Denmark)

    Sugiyama, M; Annaka, M; Hino, M


    Charge screening effects on nanostructures of N-isopropylacrylamide-sodium acrylate (NIPA-SA) and -acrylic acid (NIPA-AAc) gels are investigated with small-angle neutron scattering. The NIPA-SA and NIPA-AAc gels with low water content exhibit microphase separations with different dimensions....... The dehydrated NIPA-SA gel also makes the microphase separation but the dehydrated NIPA-AAc gel does not. These results indicate that ionic circumstance around charged bases strongly affects the nanostructures both of the dehydrated gel and the gel with low water content. (C) 2004 Elsevier B. V. All rights...

  17. Screening effect on nanostructure of charged gel

    International Nuclear Information System (INIS)

    Sugiyama, Masaaki; Annaka, Masahiko; Hino, Masahiro; Fukunaga, Toshiharu; Vigild, Martin E.; Hara, Kazuhiro


    Charge screening effects on nanostructures of N-isopropylacrylamide-sodium acrylate (NIPA-SA) and -acrylic acid (NIPA-AAc) gels are investigated with small-angle neutron scattering. The NIPA-SA and NIPA-AAc gels with low water content exhibit microphase separations with different dimensions. The dehydrated NIPA-SA gel also makes the microphase separation but the dehydrated NIPA-AAc gel does not. These results indicate that ionic circumstance around charged bases strongly affects the nanostructures both of the dehydrated gel and the gel with low water content

  18. Screening effect on nanostructure of charged gel (United States)

    Sugiyama, Masaaki; Annaka, Masahiko; Hino, Masahiro; Fukunaga, Toshiharu; E. Vigild, Martin; Hara, Kazuhiro


    Charge screening effects on nanostructures of N-isopropylacrylamide-sodium acrylate (NIPA-SA) and -acrylic acid (NIPA-AAc) gels are investigated with small-angle neutron scattering. The NIPA-SA and NIPA-AAc gels with low water content exhibit microphase separations with different dimensions. The dehydrated NIPA-SA gel also makes the microphase separation but the dehydrated NIPA-AAc gel does not. These results indicate that ionic circumstance around charged bases strongly affects the nanostructures both of the dehydrated gel and the gel with low water content.

  19. A fast charge integrating and shaping circuit

    International Nuclear Information System (INIS)

    Kulka, Z.; Szoncso, F.


    The development of a low cost fast charge integrating and shaping circuit (FCISC) was motivated by the need for an interface between the photomultipliers of an existing hadronic calorimeter and recently developed new readout electronics designed to match the output of small ionization chambers for the upgraded UA1 detector at the CERN proton-antiproton collider. This paper describes the design principles of gated and ungated charge integrating and shaping circuits. An FCISC prototype using discrete components was made and its properties were determined with a computerized test setup. Finally an SMD implementation of the FCISC is presented and the performance is reported. (orig.)

  20. Charge transfer in gold--alkali-metal systems

    International Nuclear Information System (INIS)

    Watson, R.E.; Weinert, M.


    Based on conventional electronegativity arguments, gold--alkali-metal compounds are expected to be among the most ''ionic'' of metallic compounds. The concepts of ionicity and charge transfer are difficult to quantify. However, the changes in bonding in the 50/50 Au--alkali-metal systems between the elemental metals and the compounds are so severe that observations can readily be made concerning their character. The results, as obtained from self-consistent electronic-structure calculations, lead to the apparently odd observation that the electron density at the alkali-metal sites in the compound increases significantly and this involves high l componennts in the charge density. This increase, however, can be attributed to Au-like orbitals spatially overlapping the alkali-metal sites. In a chemical sense, it is reasonable to consider the alkali-metal transferring charge to these Au orbitals. While normally the difference in heats of formation between muffin-tin and full-potential calculations for transition-metal--transition-metal and transition-metal--main-group (e.g., Al) compounds having high site symmetry are small, for the gold--alkali-metal systems, the changes in bonding in the compounds cause differences of ∼0.5 eV/atom between the two classes of potential. Any serious estimate of the electronic structure in these systems must account for these aspherical bonding charges. The origin of the semiconducting behavior of the heavy-alkali-metal Au compounds is shown to arise from a combination of the Au-Au separations and the ionic character of the compounds; the light-alkali-metal Au compounds, with their smaller Au-Au separations, do not have a semiconducting gap. Core-level shifts and isomer shifts are also briefly discussed

  1. Resident-Assisted Montessori Programming (RAMP): use of a small group reading activity run by persons with dementia in adult day health care and long-term care settings. (United States)

    Skrajner, Michael J; Camp, Cameron J


    Six persons in the early to middle stages of dementia ("leaders") were trained in Resident-Assisted Montessori Programming (RAMP) to lead a reading activity for 22 persons with more advanced dementia ("participants") in an adult day health center (ADHC) and a special care unit (SCU) in a skilled nursing facility. Researchers assessed the leaders' abilities to learn and follow the procedures of leading a group, as well as their satisfaction with their roles. In addition, participants' engagement and affect were measured, both during standard activities programming and during client-led activities. Results of this study suggest that persons with dementia can indeed successfully lead small group activities, if several important prerequisites are met. Furthermore, the engagement and affect of participants was more positive in client-led activities than in standard activities programming.

  2. Children's Reactions to Small Group Psychological Education (United States)

    Gerler, Edwin R., Jr.; Pepperman, Carl W.


    This article shows a positive reaction among students toward the Human Development Program. The study, however, raises a number of significant questions about specific aspects of the Magic Circle technique, particularly in regard to the listening that occurs in circle session. (Author)

  3. Shot Group Statistics for Small Arms Applications (United States)


    statistical inference on the unknown, population standard deviations of the x and y impact-point positions. The dispersion measures treated in this report...known with sufficient accuracy, then it can be used to make a sound statistical inference on the unknown, population standard deviations of the x and y...are the univariate measures: range, mean deviation , and standard deviation ; and the bivariate measures: extreme spread, mean radius, and radial

  4. An Investigation of Low Earth Orbit Internal Charging (United States)

    NeergaardParker, Linda; Minow, Joseph I.; Willis, Emily M.


    prescribed breakdown strength. For simplicity, the amount of charge lost in the discharge is treated as a random percentage of the total charge between a set maximum and minimum amount so a user can consider partial discharges of insulating materials (small loss of charge) or arcing from a conductor (large loss of charge). We apply the model to electron flux measurements from the NOAA-19 spacecraft to demonstrate that charging can reach levels where electrostatic discharges occur and estimate the magnitude of the discharge.

  5. Report of study group 3.2 ''small scale LNG projects and modular systems''; Rapport du groupe d'etude 3.2 ''projets de GNL a petite echelle et systemes modulaires''

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, B.


    This report details the work undertaken by Study Group 3.2 during the triennium 1997-2000. The Study Group has held three meetings in Stavanger (Norway) in Dubai (UAE) and in London (UK) between March 1998 and October 1999. The study group membership is listed in appendix 1. The subject treated by the Study Group is 'Small Scale LNG Projects and Modular Systems' The study report undertakes a general survey of: 1) the state of the art of the technology; 2) the potential market applications; 3) prospects for gas development and marginal fields. The study addresses three main items: a) Adapting regulation to compact LNG production systems (e.g. distances between equipment in fixed installations); b) LNG production in a marine environment; c) The need for substantial cost reductions. The questions that are addressed in this study report are: Will small scale LNG projects be economically viable? When an onshore industry moves offshore - which standards are to be applied? (author)

  6. Plasmon Response and Electron Dynamics in Charged Metallic Nanoparticles. (United States)

    Zapata Herrera, Mario; Aizpurua, Javier; Kazansky, Andrey K; Borisov, Andrei G


    Using the time-dependent density functional theory, we perform quantum calculations of the electron dynamics in small charged metallic nanoparticles (clusters) of spherical geometry. We show that the excess charge is accumulated at the surface of the nanoparticle within a narrow layer given by the typical screening distance of the electronic system. As a consequence, for nanoparticles in vacuum, the dipolar plasmon mode displays only a small frequency shift upon charging. We obtain a blue shift for positively charged clusters and a red shift for negatively charged clusters, consistent with the change of the electron spill-out from the nanoparticle boundaries. For negatively charged clusters, the Fermi level is eventually promoted above the vacuum level leading to the decay of the excess charge via resonant electron transfer into the continuum. We show that, depending on the charge, the process of electron loss can be very fast, on the femtosecond time scale. Our results are of great relevance to correctly interpret the optical response of the nanoparticles obtained in electrochemistry, and demonstrate that the measured shift of the plasmon resonances upon charging of nanoparticles cannot be explained without account for the surface chemistry and the dielectric environment.

  7. Charge transfer in astrophysical nebulae

    International Nuclear Information System (INIS)

    Shields, G.A.


    Charge transfer has become a standard ingredient in models of ionized nebulae, supernovae remnants and active galactic nuclei. Charge transfer rate coefficients and the physics of ionized nebulae are considered. Charge transfer is applied to the ionization structure and line emission of ionized nebulae. Photoionized nebulae observations are used to test theoretical predictions of charge transfer rates. (author)

  8. Electric vehicle battery charging controller

    DEFF Research Database (Denmark)


    to a battery management system in the electric vehicle to charge a battery therein, a first communication unit for receiving a charging message via a communication network, and a control unit for controlling a charging current provided from the charge source to the electric vehicle, the controlling at least...

  9. Dispersion and space charge

    International Nuclear Information System (INIS)

    Venturini, M.; Kishek, R.A.; Reiser, M.


    The presence of space charge affects the value of the dispersion function. On the other hand dispersion has a role in shaping the beam distribution and therefore in determining the resulting forces due to space charge. In this paper we present a framework where the interplay between space charge and dispersion for a continuous beam can be simultaneously treated. We revise the derivation of a new set of rms envelope-dispersion equations we have recently proposed in [1]. The new equations generalize the standard rms envelope equations currently used for matching to the case where bends and a longitudinal momentum spread are present. We report a comparison between the solutions of the rms envelope-dispersion equations and the results obtained using WARP, a Particle in Cell (PIC) code, in the modeling of the Maryland Electron Ring. copyright 1998 American Institute of Physics

  10. Dispersion and space charge

    Energy Technology Data Exchange (ETDEWEB)

    Venturini, M. [Department of Physics and Institute for Plasma Research, University of Maryland, College Park, Maryland 20742 (United States); Kishek, R.A.; Reiser, M. [Department of Electrical Engeneering and Institute for Plasma Research, University of Maryland, College Park, Maryland 20742 (United States)


    The presence of space charge affects the value of the dispersion function. On the other hand dispersion has a role in shaping the beam distribution and therefore in determining the resulting forces due to space charge. In this paper we present a framework where the interplay between space charge and dispersion for a continuous beam can be simultaneously treated. We revise the derivation of a new set of rms envelope-dispersion equations we have recently proposed in [1]. The new equations generalize the standard rms envelope equations currently used for matching to the case where bends and a longitudinal momentum spread are present. We report a comparison between the solutions of the rms envelope-dispersion equations and the results obtained using WARP, a Particle in Cell (PIC) code, in the modeling of the Maryland Electron Ring. {copyright} {ital 1998 American Institute of Physics.}

  11. Dispersion and space charge

    International Nuclear Information System (INIS)

    Venturini, Marco; Kishek, Rami A.; Reiser, Martin


    The presence of space charge affects the value of the dispersion function. On the other hand dispersion has a role in shaping the beam distribution and therefore in determining the resulting forces due to space charge. In this paper we present a framework where the interplay between space charge and dispersion for a continuous beam can be simultaneously treated. We revise the derivation of a new set of rms envelope-dispersion equations we have recently proposed. The new equations generalize the standard rms envelope equations currently used for matching to the case where bends and a longitudinal momentum spread are present. We report a comparison between the solutions of the rms envelope-dispersion equations and the results obtained using WARP, a Particle in Cell (PIC) code, in the modeling of the Maryland Electron Ring

  12. Colloids with continuously tunable surface charge. (United States)

    van Ravensteijn, Bas G P; Kegel, Willem K


    In this paper, we present a robust way to tune the surface potential of polystyrene colloids without changing the pH, ionic strength, etc. The colloids are composed of a cross-linked polystyrene core and a cross-linked vinylbenzyl chloride layer. Besides the chlorine groups, the particle surface contains sulfate/sulfonate groups (arising from the polymerization initiators) that provide a negative surface potential. Performing a Menschutkin reaction on the surface chlorine groups with tertiary amines allows us to introduce quaternary, positively charged amines. The overall charge on the particles is then determined by the ratio between the sulfate/sulfonate moieties and the quaternary amines. Using this process, we were able to invert the charge in a continuous manner without losing colloidal stability upon passing the isoelectric point. The straightforward reaction mechanism together with the fact that the reaction could be quenched rapidly resulted in a colloidal system in which the ζ potential can be tuned between -80 and 45 mV. As proof of principle, the positively charged particles were used in heterocoagulation experiments with nanometer- and micrometer-sized negatively charged silica particles to create geometrically well-defined colloidal (nano) clusters.

  13. Coagulation of charged particles in dust plasma

    International Nuclear Information System (INIS)

    Belov, I.A.; Ivanov, A.S.; Ivanov, D.A.; Pal', A.F.; Starostin, A.N.; Filippov, A.V.; Dem'yanov, A.V.; Petrushevich, Yu.V.


    One studied peculiarities of behaviour of small particles in dust plasma resulted on the one hand, from suppression of coagulation due to monopolar charging within the range of particle dimensions under the Debye radius of shielding and, on the other hand, from leveling of this case for particles of large dimensions. On the basis of similarity ratios one determined the range of parameters making linear approximation of particle charge dependence on their dimension true. In terms of the modified classical theory of coagulation in diffusion approximation one studied certain anomalies of behavior of dimension distribution of particles. It is determined that in contrast to the ordinary aerosol in dust plasma as time passes one may reduce dispersion of distribution and average dimensions of particles. For the first time one demonstrates the possibility to realize long-lived quasiliquid state of dust plasma associated with the anomalous behaviour of distribution function of coagulating charged particles according to dimensions [ru

  14. Methodological approach of the North-Cotentin radioecological group in charge of the evaluation of doses and risks due to the radiations exposure of the North-Cotentin population

    International Nuclear Information System (INIS)

    Sugierr, A.


    The group has evaluated and validated the list and quantities of radioelements release(source term) for each of the four nuclear installations of the North Cotentin since their beginning of operation (the reprocessing plant of Cogema la Hague, the Flamanville nuclear power plant, the Manche storage plant and the arsenal of the Cherbourg harbour). The gathering of data relative to radionuclides in environment of the north Cotentin has allowed from one hand the publication of samples inventory and types of radioactivity measurements and in an other hand an analysis of the results. The intercomparison of transfer models in environment and the confrontation of their results with the measures have been used for the doses calculations to the references groups and to the children troop from the Beaumont-Hague district. Finally, the elements necessary to the doses and risks estimation have been itemized and validated. One of the questions that stands out of these works is this one of the aims of the surveillance and measurements in environment according to the different organisms that realize them. It is important to make the distinction between the routine measurements ( to be sure of the correct operation of the facility and that the authorized release limits are well respected) and the measurements that allow to reconstitute the dose to population groups. (N.C.)

  15. Sources for charged particles

    International Nuclear Information System (INIS)

    Arianer, J.


    This document is a basic course on charged particle sources for post-graduate students and thematic schools on large facilities and accelerator physics. A simple but precise description of the creation and the emission of charged particles is presented. This course relies on every year upgraded reference documents. Following relevant topics are considered: electronic emission processes, technological and practical considerations on electron guns, positron sources, production of neutral atoms, ionization, plasma and discharge, different types of positive and negative ion sources, polarized particle sources, materials for the construction of ion sources, low energy beam production and transport. (N.T.)

  16. Charged conformal Killing spinors

    Energy Technology Data Exchange (ETDEWEB)

    Lischewski, Andree, E-mail: [Humboldt-Universität zu Berlin, Institut für Mathematik, Rudower Chaussee 25, Room 1.310, D12489 Berlin (Germany)


    We study the twistor equation on pseudo-Riemannian Spin{sup c}-manifolds whose solutions we call charged conformal Killing spinors (CCKSs). We derive several integrability conditions for the existence of CCKS and study their relations to spinor bilinears. A construction principle for Lorentzian manifolds admitting CCKS with nontrivial charge starting from CR-geometry is presented. We obtain a partial classification result in the Lorentzian case under the additional assumption that the associated Dirac current is normal conformal and complete the classification of manifolds admitting CCKS in all dimensions and signatures ≤5 which has recently been initiated in the study of supersymmetric field theories on curved space.

  17. Space-charge dynamics in ultra-cold ion bunches (United States)

    Scholten, Robert; Murphy, Dene; Speirs, Rory; Thompson, Daniel; Sparkes, Benjamin; McCulloch, Andrew


    Cold ion sources based on photoionisation of laser cooled atoms provide a unique system for investigating Coulomb interactions within complex charged particle bunches. Space-charge driven expansion in charged particle beams is of critical importance for applications including electron and ion microscopy, mass spectrometry, synchrotrons and x-ray free electron lasers, and in electron diffraction where space-charge effects constrain the capacity to obtain diffraction information. Self-field effects are often difficult to observe because of thermal diffusion with traditional sources. Cold atom sources produce ions with temperatures of a few mK, such that subtle space-charge effects are apparent. We illustrate the capabilities through detailed investigation of a complex ion bunch shape, showing collective behaviour including high density caustics and shockwave structures arising from long-range interactions between small charge bunches.

  18. Working Group Report: Neutrinos

    Energy Technology Data Exchange (ETDEWEB)

    de Gouvea, A.; Pitts, K.; Scholberg, K.; Zeller, G. P. [et al.


    This document represents the response of the Intensity Frontier Neutrino Working Group to the Snowmass charge. We summarize the current status of neutrino physics and identify many exciting future opportunities for studying the properties of neutrinos and for addressing important physics and astrophysics questions with neutrinos.

  19. MOVES Model Review Work Group (United States)

    The FACA MOVES Review Work Group was formed under the Mobile Sources Technical Review Subcommittee (MSTRS), and is charged to provide input to EPA via the MSTRS and the Clean Air Act Advisory Committee on specific issues regarding MOVES development.

  20. A Charge Parity Ammeter (United States)

    Lambert, Nicholas J.; Edwards, Megan; Ciccarelli, Chiara; Ferguson, Andrew J.


    A metallic double-dot is measured with radio frequency reflectometry. Changes in the total electron number of the double-dot are determined via single electron tunnelling contributions to the complex electrical impedance. Electron counting experiments are performed by monitoring the impedance, demonstrating operation of a single electron ammeter without the need for external charge detection.