WorldWideScience

Sample records for slow-gating intensified charge-coupled

  1. Data processing correction of the irising effect of a fast-gating intensified charge-coupled device on laser-pulse-excited spectra

    Czech Academy of Sciences Publication Activity Database

    Ondič, Lukáš; Dohnalová, Kateřina; Pelant, Ivan; Žídek, K.; de Boer, W.D.A.M.

    2010-01-01

    Roč. 81, č. 6 (2010), 063104/1-063104/5 ISSN 0034-6748 R&D Projects: GA AV ČR KAN400100701; GA AV ČR(CZ) IAA101120804; GA MŠk LC510; GA AV ČR KJB100100903 Institutional research plan: CEZ:AV0Z10100521 Keywords : irising effect * intensifier charge-coupled device Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.598, year: 2010

  2. Correction method and software for image distortion and nonuniform response in charge-coupled device-based x-ray detectors utilizing x-ray image intensifier

    International Nuclear Information System (INIS)

    Ito, Kazuki; Kamikubo, Hironari; Yagi, Naoto; Amemiya, Yoshiyuki

    2005-01-01

    An on-site method of correcting the image distortion and nonuniform response of a charge-coupled device (CCD)-based X-ray detector was developed using the response of the imaging plate as a reference. The CCD-based X-ray detector consists of a beryllium-windowed X-ray image intensifier (Be-XRII) and a CCD as the image sensor. An image distortion of 29% was improved to less than 1% after the correction. In the correction of nonuniform response due to image distortion, subpixel approximation was performed for the redistribution of pixel values. The optimal number of subpixels was also discussed. In an experiment with polystyrene (PS) latex, it was verified that the correction of both image distortion and nonuniform response worked properly. The correction for the 'contrast reduction' problem was also demonstrated for an isotropic X-ray scattering pattern from the PS latex. (author)

  3. Data processing correction of the irising effect of a fast-gating intensified charge-coupled device on laser-pulse-excited luminescence spectra.

    Science.gov (United States)

    Ondic, L; Dohnalová, K; Pelant, I; Zídek, K; de Boer, W D A M

    2010-06-01

    Intensified charge-coupled devices (ICCDs) comprise the advantages of both fast gating detectors and spectrally broad CCDs into one device that enables temporally and spectrally resolved measurements with a few nanosecond resolution. Gating of the measured signal occurs in the image intensifier tube, where a high voltage is applied between the detector photocathode and a microchannel plate electron multiplier. An issue arises in time-resolved luminescence spectroscopy when signal onset characterization is required. In this case, the transient gate closing process that causes the detected signal always arises in the middle of the ICCD chip regardless of the spectral detection window--the so-called irising effect. We demonstrate that in case when the detection gate width is comparable to the opening/closing time and the gate is pretriggered with respect to the signal onset, the irising effect causes the obtained data to be strongly distorted. At the same time, we propose a software procedure that leads to the spectral correction of the irising effect and demonstrate its validity on the distorted data.

  4. Isolation Mounting for Charge-Coupled Devices

    Science.gov (United States)

    Goss, W. C.; Salomon, P. M.

    1985-01-01

    CCD's suspended by wires under tension. Remote thermoelectric cooling of charge coupled device allows vibration isolating mounting of CCD assembly alone, without having to suspend entire mass and bulk of thermoelectric module. Mounting hardware simple and light. Developed for charge-coupled devices (CCD's) in infrared telescope support adaptable to sensors in variety of environments, e.g., sensors in nuclear reactors, engine exhausts and plasma chambers.

  5. Camera memory study for large space telescope. [charge coupled devices

    Science.gov (United States)

    Hoffman, C. P.; Brewer, J. E.; Brager, E. A.; Farnsworth, D. L.

    1975-01-01

    Specifications were developed for a memory system to be used as the storage media for camera detectors on the large space telescope (LST) satellite. Detectors with limited internal storage time such as intensities charge coupled devices and silicon intensified targets are implied. The general characteristics are reported of different approaches to the memory system with comparisons made within the guidelines set forth for the LST application. Priority ordering of comparisons is on the basis of cost, reliability, power, and physical characteristics. Specific rationales are provided for the rejection of unsuitable memory technologies. A recommended technology was selected and used to establish specifications for a breadboard memory. Procurement scheduling is provided for delivery of system breadboards in 1976, prototypes in 1978, and space qualified units in 1980.

  6. Radiation effects in charge coupled devices

    International Nuclear Information System (INIS)

    Williams, R.A.; Nelson, R.D.

    1975-01-01

    Charge coupled devices (CCD s) exhibit a number of advantages (low cost, low power, high bit density) in their several applications (serial memories, imagers, digital filters); however, fairly elementary theoretical considerations indicate that they will be very vulnerable to permanent radiation damage, by both neutrons and ionizing radiation, and to transient upset by pulsed ionizing radiation. Although studies of permanent ionizing-radiation damage in CCD's have been reported, little information has been published concerning their overall nuclear radiation vulnerability. This paper presents a fairly comprehensive experimental study of radiation effects in a 256-cell surface-channel, CCD shift-register. A limited amount of similar work is also presented for a 128-cell surface-channel device and a 130 cell peristaltic CCD shift register. The radiation effects phenomena discussed herein, include transient-ionizing-radiation responses, permanent ionizing- radiation damage to transfer efficiency, charge-carrying capacity and input transfer gate bias, and neutron damage to storage time--determined from dark current and charge-up time measurements

  7. Charge-coupled device area detector for low energy electrons

    Czech Academy of Sciences Publication Activity Database

    Horáček, Miroslav

    2003-01-01

    Roč. 74, č. 7 (2003), s. 3379 - 3384 ISSN 0034-6748 R&D Projects: GA ČR GA102/00/P001 Institutional research plan: CEZ:AV0Z2065902 Keywords : low energy electrons * charged-coupled device * detector Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 1.343, year: 2003

  8. Microcomputer based test system for charge coupled devices

    International Nuclear Information System (INIS)

    Sidman, S.

    1981-02-01

    A microcomputer based system for testing analog charge coupled integrated circuits has been developed. It measures device performance for three parameters: dynamic range, baseline shift due to leakage current, and transfer efficiency. A companion board tester has also been developed. The software consists of a collection of BASIC and assembly language routines developed on the test system microcomputer

  9. A comparison of charged coupled devices and film sensitivities

    International Nuclear Information System (INIS)

    Wallick, W.O.; Kenyon, R.G.; Lubatti, H.J.

    1977-01-01

    The response of a charged coupled device (Fairchild CCD-202) to a Ne light source is studied and compared to the Kodak SO-143 film commonly used for streamer chamber applications. It is found that the CCD-202 cooled to - 10 0 C is considerebly more sensitive than the film. The advantages of using a CCD camera system for streamer chamber and other applications is discussed. (Auth.)

  10. Improvements in or relating to charge coupled devices

    International Nuclear Information System (INIS)

    Shannon, J.M.

    1980-01-01

    This invention relates to charge coupled devices for converting an electromagnetic radiation pattern in a certain wavelength range, particularly but not exclusively an infrared radiation pattern, into electrical signals. A semiconductor layer within this device can be of n-type silicon with a deep level impurity concentration present as proton bombardment induced defects in the crystal lattice or as an ion implanted concentration. (UK)

  11. Evaluation of charge coupled devices as alpha particle detectors

    International Nuclear Information System (INIS)

    Pace, R.; Haskard, M.; Watts, S.; Holmes-Siedle, A.; Solanky, M.

    1996-01-01

    The ability of the Charge Coupled Device (CCD) to provide spectroscopic and flux information for highly ionising radiation has been investigated. CCDs and related imaging chips are becoming increasingly affordable. In addition advances in technology are producing smaller and better devices. Since imaging chips are based on some variation of the pn-diode structure it is expected and known that they are sensitive to ionising radiation as well as light. Indeed specially designed CCDs are able to be used to image X-rays. This paper reports on the response of CCDs to alpha particles. (author)

  12. Combining Charge Couple Devices and Rate Sensors for the Feedforward Control System of a Charge Coupled Device Tracking Loop.

    Science.gov (United States)

    Tang, Tao; Tian, Jing; Zhong, Daijun; Fu, Chengyu

    2016-06-25

    A rate feed forward control-based sensor fusion is proposed to improve the closed-loop performance for a charge couple device (CCD) tracking loop. The target trajectory is recovered by combining line of sight (LOS) errors from the CCD and the angular rate from a fiber-optic gyroscope (FOG). A Kalman filter based on the Singer acceleration model utilizes the reconstructive target trajectory to estimate the target velocity. Different from classical feed forward control, additive feedback loops are inevitably added to the original control loops due to the fact some closed-loop information is used. The transfer function of the Kalman filter in the frequency domain is built for analyzing the closed loop stability. The bandwidth of the Kalman filter is the major factor affecting the control stability and close-loop performance. Both simulations and experiments are provided to demonstrate the benefits of the proposed algorithm.

  13. Optimizing low-light microscopy with back-illuminated electron multiplying charge-coupled device: enhanced sensitivity, speed, and resolution.

    Science.gov (United States)

    Coates, Colin G; Denvir, Donal J; McHale, Noel G; Thornbury, Keith D; Hollywood, Mark A

    2004-01-01

    The back-illuminated electron multiplying charge-coupled device (EMCCD) camera is having a profound influence on the field of low-light dynamic cellular microscopy, combining highest possible photon collection efficiency with the ability to virtually eliminate the readout noise detection limit. We report here the use of this camera, in 512 x 512 frame-transfer chip format at 10-MHz pixel readout speed, in optimizing a demanding ultra-low-light intracellular calcium flux microscopy setup. The arrangement employed includes a spinning confocal Nipkow disk, which, while facilitating the need to both generate images at very rapid frame rates and minimize background photons, yields very weak signals. The challenge for the camera lies not just in detecting as many of these scarce photons as possible, but also in operating at a frame rate that meets the temporal resolution requirements of many low-light microscopy approaches, a particular demand of smooth muscle calcium flux microscopy. Results presented illustrate both the significant sensitivity improvement offered by this technology over the previous standard in ultra-low-light CCD detection, the GenIII+intensified charge-coupled device (ICCD), and also portray the advanced temporal and spatial resolution capabilities of the EMCCD. Copyright 2004 Society of Photo-Optical Instrumentation Engineers.

  14. Charge-coupled device area detector for low energy electrons

    International Nuclear Information System (INIS)

    Horacek, Miroslav

    2003-01-01

    A fast position-sensitive detector was designed for the angle- and energy-selective detection of signal electrons in the scanning low energy electron microscope (SLEEM), based on a thinned back-side directly electron-bombarded charged-coupled device (CCD) sensor (EBCCD). The principle of the SLEEM operation and the motivation for the development of the detector are explained. The electronics of the detector is described as well as the methods used for the measurement of the electron-bombarded gain and of the dark signal. The EBCCD gain of 565 for electron energy 5 keV and dynamic range 59 dB for short integration time up to 10 ms at room temperature were obtained. The energy dependence of EBCCD gain and the detection efficiency are presented for electron energy between 2 and 5 keV, and the integration time dependence of the output signals under dark conditions is given for integration time from 1 to 500 ms

  15. A new clocking method for a charge coupled device

    International Nuclear Information System (INIS)

    Umezu, Rika; Kitamoto, Shunji; Murakami, Hiroshi

    2014-01-01

    We propose and demonstrate a new clocking method for a charge-coupled device (CCD). When a CCD is used for a photon counting detector of X-rays, its weak point is a limitation of its counting rate, because high counting rate makes non-negligible pile-up of photons. In astronomical usage, this pile-up is especially severe for an observation of a bright point-like object. One typical idea to reduce the pile-up is a parallel sum (P-sum) mode. This mode completely loses one-dimensional information. Our new clocking method, panning mode, provides complementary properties between the normal mode and the P-sum mode. We performed a simple simulation in order to investigate a pile-up probability and compared the simulated result and actual obtained event rates. Using this simulation and the experimental results, we compared the pile-up tolerance of various clocking modes including our new method and also compared their other characteristics

  16. Thermodynamic studies on charge-coupled substituted synthetic monazite

    Energy Technology Data Exchange (ETDEWEB)

    Rawat, D. [Product Development Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085 (India); Phapale, S. [Chemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085 (India); Mishra, R., E-mail: mishrar@barc.gov.in [Chemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085 (India); Dash, S. [Product Development Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085 (India)

    2017-04-15

    Phosphate-based monazite ceramic is considered worldwide as a potential crystalline host matrix for immobilization of long-lived tri- and tetra-valent actinides present in high-level nuclear waste. Monazite is chemically stable with respect to the leaching processes and has high radiation stability. The present paper describes the influence of charged coupled (Ca{sup 2+}, Th{sup 4+}) substitution in place of La{sup 3+} on thermodynamic stability of synthetic monazite ceramics. XRD-analysis of Ca, Th substituted LaPO{sub 4} viz., La{sub 1-x}Ca{sub x/2}Th{sub x/2}PO{sub 4} (0 ≤ x ≤ 1) points to the formation of ideal solid-solution in the entire range of composition. However, thermodynamic analysis indicates deviation from ideal solid-solution with a minima at x = 0.25. The substituted La{sub 1-x}Ca{sub x/2}Th{sub x/2}PO{sub 4} system is found to be iso-entropic and stabilized mainly by enthalpy. Enthalpies of formation as a function of Ca{sup 2+}, Th{sup 4+} substitution were analysed to provide insights into the development of thermodynamically stable nuclear waste matrix.

  17. A surface diffuse scattering model for the mobility of electrons in surface charge coupled devices

    International Nuclear Information System (INIS)

    Ionescu, M.

    1977-01-01

    An analytical model for the mobility of electrons in surface charge coupled devices is studied on the basis of the results previously obtained, considering a surface diffuse scattering; the importance of the results obtained for a better understanding of the influence of the fringing field in surface charge coupled devices is discussed. (author)

  18. Value of intensified nursing

    OpenAIRE

    Raymann, Cornelia; Konta, Brigitte; Prusa, Nina; Frank, Wilhelm

    2006-01-01

    The concept "intensified nursing" is mentioned in differentiation to concepts of "nursing care" or "nursing" which intensifies resources or patient contact. Especially psychic and social needs of patients are very appreciated in nursing. A similar type of nursing is known under the concept "advanced nursing practice" (ANP) which means, that a specialised, academically trained nurse offers an extended nursing care in which a focus on the published knowledge of evidence based research is made. ...

  19. Fluoroscopy without image intensifier

    International Nuclear Information System (INIS)

    Canevaro, L.; Drexler, G.

    2001-01-01

    The objective of the present work was to evaluate the doses received by patients during fluoroscopy procedures carried out with an equipment without image intensifier. This evaluation is providing dose levels that our patients are presently exposed, and gives the data for epidemiological studies on risk estimate of cancer induction in patients exposed earlier when no image intensifiers existed. Diamentor M4 and E meters were used to measure the product dose-area (DAP). The data were acquired during barium enema, barium meal, barium swallow and histerosalpingographies. The measured values of DAP are considered high. This work intends to call the attention toward the optimization of the radiological protection in facilities that still use equipment without image intensifiers. While this equipment cannot be disabled, the patient exposure monitoring should be an incentive, and the application of radiological protection practices and programs of quality assurance should be of priority. (author)

  20. Neutron image intensifier tubes

    International Nuclear Information System (INIS)

    Verat, M.; Rougeot, H.; Driard, B.

    1983-01-01

    The most frequently used techniques in neutron radiography employ a neutron converter consisting of either a scintillator or a thin metal sheet. The radiation created by the neutrons exposes a photographic film that is in contact with the converter: in the direct method, the film is exposed during the time that the object is irradiated with neutrons; in the transfer method, the film is exposed after the irradiation of the object with neutrons. In industrial non-destructive testing, when many identical objects have to be checked, these techniques have several disadvantages. Non-destructive testing systems without these disadvantages can be constructed around neutron-image intensifier tubes. A description and the operating characteristics of neutron-image intensifier tubes are given. (Auth.)

  1. Radiographic intensifying screens

    International Nuclear Information System (INIS)

    Van Landeghem, W.K.; Suys, A.R.

    1979-01-01

    A fluorescent x-ray image intensifying screen is described which comprises discrete particles of fluorescent material dispersed in a binder layer. Intensifying screens are employed to increase the exposure of a photosensitive plate or film without increasing the x-ray exposure dose when struck by x-rays. The screen has an outermost layer containing solid particulate material protruding from a coherent film-forming organic binder medium and having a static friction coefficient at room temperature not higher than 0.50 on steel. The outermost layer may be characterized by micro-unevennesses of at least 3 μm and at least 9 protruding particles per 0.35 sq. cm. These particles have a static friction coefficient less than 0.3 and are made of a solid polystyrene, polyaklylene and/or a solid organic fluorinated polymer. (JTA)

  2. A fast charge coupled device detector for charge exchange recombination spectroscopy on the DIII-D Tokamak

    International Nuclear Information System (INIS)

    Thomas, D.M.; Burrell, K.H.; Groebner, R.J.; Gohil, P.; Kaplan, D.; Makariou, C.; Seraydarian, R.P.

    1997-01-01

    Charge exchange recombination (CER) spectroscopy has become a standard diagnostic for Tokamaks. CER measurements have been used to determine spatially and temporally resolved ion temperature, toroidal and poloidal ion rotation speed, impurity density, and radial electric field. Knowledge of the spatial profile and temporal evolution of the electric field shear in the plasma edge is crucial to understanding the physics of the L to H transition. High speed CER measurements are also valuable for edge localized mode studies. Since the 0.52 ms minimum time resolution of our present system is barely adequate to study the time evolution of these phenomena, we have developed a new charge coupled device (CCD) detector system with about a factor of 2 better time resolution. In addition, our existing system detects sufficient photons to utilize the shortest time resolution only under exceptional conditions. The new CCD detector has a quantum efficiency of about 0.65, which is a factor of 7 better than our previous image intensifier-silicon photodiode detector systems. We have also equipped the new system with spectrometers of lower f/number. This combination should allow more routine operation at the minimum integration time, as well as improving data quality for measurements in the divertor-relevant region outside of the separatrix. Construction details, benchmark data, and initial Tokamak measurements for the new system will be presented. copyright 1997 American Institute of Physics

  3. Improved charge-coupled device detectors for high-speed, charge exchange spectroscopy studies on the DIII-D tokamak

    International Nuclear Information System (INIS)

    Burrell, K.H.; Gohil, P.; Groebner, R.J.; Kaplan, D.H.; Robinson, J.I.; Solomon, W.M.

    2004-01-01

    Charge exchange spectroscopy is one of the key ion diagnostics on the DIII-D tokamak. It allows determination of ion temperature, poloidal and toroidal velocity, impurity density, and radial electric field E r throughout the plasma. For the 2003 experimental campaign, we replaced the intensified photodiode array detectors on the central portion of the DIII-D charge exchange spectroscopy system with advanced charge-coupled device (CCD) detectors mounted on faster (f/4.7) Czerny-Turner spectrometers equipped with toroidal mirrors. The CCD detectors are improved versions of the ones installed on our edge system in 1999. The combination improved the photoelectron signal level by about a factor of 20 and the signal to noise by a factor of 2-8, depending on the absolute signal level. The new cameras also allow shorter minimum integration times while archiving to PC memory: 0.552 ms for the slower, lower-read noise (15 e) readout mode and 0.274 ms in the faster, higher-read noise (30 e) mode

  4. Features of the use of charge-coupled devices in emission spectroscopic analysis

    International Nuclear Information System (INIS)

    Livshits, A.M.; Peleznev, A.V.

    1993-01-01

    Multielement radiation receivers based on linear charge-coupled photodiode devices have become more aand more widely used recently in spectroscopic analysis. The main feature of such receivers is their ability to record not only the intensity of the incident light flux, but also its spatial distribution. This article considers the advantages and disadvantages of charge-coupled devices when used in emission spectroscopic analysis. The main methods nd devices employed for this purpose and discussed here can be divided into four types: photographic photometry, visual styloscopy, quantometry, and successive analysis. 4 refs., 1 fig

  5. Processing of poly-Si electrodes for charge-coupled devices

    Energy Technology Data Exchange (ETDEWEB)

    Sherohman, J.W.; Cook, F.D.

    1978-12-06

    A technique has been developed to fabricate poly-Si electrodes for charge-coupled devices. By controlling the microstructure of a poly-Si film, an anisotropic etchant was selected to provide essentially uniform electrode width dimensions. The electrode widths have only a 6% variation for the majority of the devices over the area of a 2 inch silicon wafer.

  6. Evaluation of a charged coupled device camera for streamer chamber applications

    International Nuclear Information System (INIS)

    Holmgren, D.; Wallick, W.; Kenyon, R.; Lubatti, H.J.

    1978-01-01

    The response of a charged coupled device to a Ne light source is studied and compared to the Kodak SO-143 film commonly used for streamer chamber applications. It is found that the CCD-202 cooled to -10 0 C is considerably more sensitive than the film. A test of a CCD-based measurement system observing a streamer chamber is described. 3 refs

  7. The quantic distribution of mobile carriers in a surface charge coupled device

    International Nuclear Information System (INIS)

    Ionescu, M.

    1977-01-01

    The quantic distribution of the electrons in a surface charge coupled device (CCD), for a MIS structure with a real insulator (finite difference energy between the conduction bands of the insulator and of the semiconductor) is presented. A fundamental limitation of the charge transfer in a surface CCD is obtained. (author)

  8. The application of charge-coupled device processors in automatic-control systems

    Science.gov (United States)

    Mcvey, E. S.; Parrish, E. A., Jr.

    1977-01-01

    The application of charge-coupled device (CCD) processors to automatic-control systems is suggested. CCD processors are a new form of semiconductor component with the unique ability to process sampled signals on an analog basis. Specific implementations of controllers are suggested for linear time-invariant, time-varying, and nonlinear systems. Typical processing time should be only a few microseconds. This form of technology may become competitive with microprocessors and minicomputers in addition to supplementing them.

  9. Charge-coupled devices for particle detection with high spatial resolution

    International Nuclear Information System (INIS)

    Farley, F.J.; Damerell, C.J.S.; Gillman, A.R.; Wickens, F.J.

    1980-10-01

    The results of a study of the possible application of a thin microelectronic device (the charge-coupled device) to high energy physics as particle detectors with good spatial resolution which can distinguish between tracks emerging from the primary vertex and those from secondary vertices due to the decay of short lived particles with higher flavours, are reported. Performance characteristics indicating the spatial resolution, particle discrimination, time resolution, readout time and lifetime of such detectors have been obtained. (U.K.)

  10. A high-resolution detector based on liquid-core scintillating fibres with readout via an electron-bombarded charge-coupled device

    International Nuclear Information System (INIS)

    Cianfarani, C.; Duane, A.; Fabre, J.P.; Frenkel, A.; Golovkin, S.V.; Gorin, A.M.; Harrison, K.; Kozarenko, E.N.; Kushnirenko, A.E.; Ladygin, E.A.; Martellotti, G.; Medvedkov, A.M.; Nass, P.A.; Obudovski, V.P.; Penso, G.; Petukhov, Yu.P.; Siegmund, W.P.; Tyukov, V.E.; Vasilchenko, V.G.

    1994-01-01

    This paper is a presentation of results from tests in a 5 GeV/c hadron beam of detectors based on liquid-core scintillating fibres, each fibre consisting of a glass capillary filled with organic liquid scintillator. Fibre readout was performed via an Electron-Bombarded Charge-Coupled Device (EBCCD) image tube, a novel instrument that combines the functions of a high-gain, gated image intensifier and a Charge-Coupled Device. Using 1-methylnaphthalene doped with 3 g/l of R45 as liquid scintillator, the attenuation lengths obtained for light propagation over distances greater than 16 cm were 1.5 m in fibres of 20 μm core and 1.0 m in fibres of 16 μm core. For particles that crossed the fibres of 20 μm core at distances of ∼1.8 cm and ∼95 cm from the fibres' readout ends, the recorded hit densities were 5.3 mm -1 and 2.5 mm -1 respectively. Using 1-methylnaphthalene doped with 3.6 g/l of R39 as liquid scintillator and fibres of 75 μm core, the hit density obtained for particles that crossed the fibres at a distance of ∼1.8 cm from their readout ends was 8.5 mm -1 . With a specially designed bundle of tapered fibres, having core diameters that smoothly increase from 16 μm to 75 μm, a spatial precision of 6 μm was measured. (orig.)

  11. Measuring a narrow Bessel beam spot by scanning a charge-coupled device (CCD) pixel

    International Nuclear Information System (INIS)

    Tiwari, S K; Ram, S P; Jayabalan, J; Mishra, S R

    2010-01-01

    By scanning a charge-coupled device (CCD) camera transverse to the beam axis and observing the variation in counts on a marked pixel, we demonstrate that we can measure a laser beam spot size smaller than the size of the CCD-pixel. We find this method particularly attractive for measuring the size of central spot of a Bessel beam, for which the established scanning knife-edge method does not work appropriately because of the large contribution of the rings surrounding the central spot to the signal

  12. Photon attenuation by intensifying screens

    International Nuclear Information System (INIS)

    Holje, G.

    1983-01-01

    The photon attenuation by intensifying screens of different chemical composition has been determined. The attenuation of photons between 20 keV and 120 keV was measured by use of a multi-channel analyzer and a broad bremsstrahlung distribution. The attenuation by the intensifying screens was hereby determined simultaneously at many different monoenergetic photon energies. Experimentally determined attenuations were found to agree well with attenuation calculated from mass attenuation coefficients. The attenuation by the screens was also determined at various bremsstrahlung distributions, simulating those occurring behind the patient in various diagnostic X-ray examinations. The high attenuation in some of the intensifying screens form the basis for an analysis of the construction of asymmetric screen pairs. Single screen systems are suggested as a favourable alternative to thick screen pair systems. (Author)

  13. Intensifying screens in transaxial tomography

    International Nuclear Information System (INIS)

    Debelder, M.H.; Bollen, R.H.

    1981-01-01

    This patent claim by Agfa-Gevaert relates to a method for the production of transaxial tomographs, a combination of materials therefor and X-ray intensifying screens incorporating at least one reflecting element for use in transaxial tomography, wherein the exposure of a photographic silver halide emulsion material proceeds at an angle within the range of 2 0 to 10 0 in conjunction with an X-ray fluorescent intensifying screen including an ultra-violet and/or visible radiation reflective coating or sheet to increase the radiation output of the screen and to reduce the exposure time and radiation dose e.g. in medical X-ray applications. (author)

  14. PRESBYOPIA OPTOMETRY METHOD BASED ON DIOPTER REGULATION AND CHARGE COUPLE DEVICE IMAGING TECHNOLOGY.

    Science.gov (United States)

    Zhao, Q; Wu, X X; Zhou, J; Wang, X; Liu, R F; Gao, J

    2015-01-01

    With the development of photoelectric technology and single-chip microcomputer technology, objective optometry, also known as automatic optometry, is becoming precise. This paper proposed a presbyopia optometry method based on diopter regulation and Charge Couple Device (CCD) imaging technology and, in the meantime, designed a light path that could measure the system. This method projects a test figure to the eye ground and then the reflected image from the eye ground is detected by CCD. The image is then automatically identified by computer and the far point and near point diopters are determined to calculate lens parameter. This is a fully automatic objective optometry method which eliminates subjective factors of the tested subject. Furthermore, it can acquire the lens parameter of presbyopia accurately and quickly and can be used to measure the lens parameter of hyperopia, myopia and astigmatism.

  15. Study of a charge-coupled device for high-energy-particle detection

    International Nuclear Information System (INIS)

    Bhuiya, A.H.

    1983-05-01

    This presentation is based on measurements made to evaluate the application of charge-coupled devices as detectors of high-energy particles. The experiment was performed with a Fairchild Linear 256-Cell CCD111 array (size 8μm x 17 μm/cell), utilizing a light source instead of a particle beam. It was observed that the minimum detectable signal was limited to approx. 488 electrons at -50 0 C, where the readout and exposure times were about 260 ms and 400 ms respectively. The transfer inefficiency of the CCD111 was determined to be approx. 10 -4 . It has been concluded that at a lower temperature (approx. -100 0 C) or with faster readout (approx. 10 ms), the CCD111 would be able to detect the total deposited energy of minimum-ionizing charged particles

  16. Spatial distribution of electrons on a superfluid helium charge-coupled device

    International Nuclear Information System (INIS)

    Takita, Maika; Bradbury, F R; Lyon, S A; Gurrieri, T M; Wilkel, K J; Eng, Kevin; Carroll, M S

    2012-01-01

    Electrons floating on the surface of superfluid helium have been suggested as promising mobile spin qubits. Three micron wide channels fabricated with standard silicon processing are filled with superfluid helium by capillary action. Photoemitted electrons are held by voltages applied to underlying gates. The gates are connected as a 3-phase charge-coupled device (CCD). Starting with approximately one electron per channel, no detectable transfer errors occur while clocking 10 9 pixels. One channel with its associated gates is perpendicular to the other 120, providing a CCD which can transfer electrons between the others. This perpendicular channel has not only shown efficient electron transport but also serves as a way to measure the uniformity of the electron occupancy in the 120 parallel channels.

  17. Fast charged-coupled device spectrometry using zoom-wavelength optics

    International Nuclear Information System (INIS)

    Carolan, P.G.; Conway, N.J.; Bunting, C.A.; Leahy, P.; OConnell, R.; Huxford, R.; Negus, C.R.; Wilcock, P.D.

    1997-01-01

    Fast charge-coupled device (CCD) detector arrays placed at the output of visible spectrometers are used for multichord Doppler shift analyses on the COMPASS-D and START tokamaks. Unequal magnification in the horizontal and vertical axes allows for optimal matching of throughput and spectral resolution at the CCD detector. This involves cylindrical lenses in an anamorphic mounting. Optical acuity is preserved over a very wide range of wavelengths (220 nm→700 nm) by separate repositioning of all the optical elements which is accomplished by the use of zoom mechanisms. This facilitates rapid changes of wavelength allowing edge and core observations depending on the location of the emitting impurity ions. Changes to the ion temperature and velocity are recorded using 20 chords simultaneously with typical accuracies of Δv i -1 and ΔT i /T i <10% with a time resolution of <1 ms. copyright 1997 American Institute of Physics

  18. Hardware implementation of adaptive filtering using charge-coupled devices. [For perimeter security sensors

    Energy Technology Data Exchange (ETDEWEB)

    Donohoe, G.W.

    1977-01-01

    Sandia Laboratories' Digital Systems Division/1734, as part of its work on the Base and Installation Security Systems (BISS) program has been making use of adaptive digital filters to improve the signal-to-noise ratio of perimeter sensor signals. In particular, the Widrow-Hoff least-mean-squares algorithm has been used extensively. This non-recursive linear predictor has been successful in extracting aperiodic signals from periodic noise. The adaptive filter generates a predictor signal which is subtracted from the input signal to produce an error signal. The value of this error is fed back to the filter to improve the quality of the next prediction. Implementation of the Widrow adaptive filter using a Charge-Coupled Device tapped analog delay line, analog voltage multipliers and operational amplifiers is described. The resulting filter adapts to signals with frequency components as high as several megahertz.

  19. Solid thin film materials for use in thin film charge-coupled devices

    International Nuclear Information System (INIS)

    Lynch, S.J.

    1983-01-01

    Solid thin films deposited by vacuum deposition were evaluated to ascertain their effectiveness for use in the manufacturing of charge-coupled devices (CCDs). Optical and electrical characteristics of tellurium and Bi 2 Te 3 solid thin films were obtained in order to design and to simulate successfully the operation of thin film (TF) CCDs. In this article some of the material differences between single-crystal material and the island-structured thin film used in TFCCDs are discussed. The electrical parameters were obtained and tabulated, e.g. the mobility, conductivity, dielectric constants, permittivity, lifetime of holes and electrons in the thin films and drift diffusion constants. The optical parameters were also measured and analyzed. After the design was complete, experimental TFCCDs were manufactured and were successfully operated utilizing the aforementioned solid thin films. (Auth.)

  20. Charged Coupled Device Debris Telescope Observations of the Geosynchronous Orbital Debris Environment - Observing Year: 1998

    Science.gov (United States)

    Jarvis, K. S.; Thumm, T. L.; Matney, M. J.; Jorgensen, K.; Stansbery, E. G.; Africano, J. L.; Sydney, P. F.; Mulrooney, M. K.

    2002-01-01

    NASA has been using the charged coupled device (CCD) debris telescope (CDT)--a transportable 32-cm Schmidt telescope located near Cloudcroft, New Mexico-to help characterize the debris environment in geosynchronous Earth orbit (GEO). The CDT is equipped with a SITe 512 x 512 CCD camera whose 24 m2 (12.5 arc sec) pixels produce a 1.7 x 1.7-deg field of view. The CDT system can therefore detect l7th-magnitude objects in a 20-sec integration corresponding to an approx. 0.6-m diameter, 0.20 albedo object at 36,000 km. The telescope pointing and CCD operation are computer controlled to collect data automatically for an entire night. The CDT has collected more than 1500 hrs of data since November 1997. This report describes the collection and analysis of 58 nights (approx. 420 hrs) of data acquired in 1998.

  1. X-ray intensifying screens

    International Nuclear Information System (INIS)

    Bossomaier, T.R.J.; Sangway, P.C.

    1979-01-01

    It is claimed that stabilization of X-ray intensifying screens against discolouration and hydrolysis of lanthanum or gadolinium oxyhalide phosphors can be achieved by incorporating into the phosphor/binder formulation a compound containing free epoxy groups. Suitable epoxy compounds include gamma glycidoxy trimethoxy silane and dimethyl di(m-glycidoxy methylphenyl) methane. The oxyhalide may be activated by Tb, Tm or Yb and may be mixed with other phosphors. Plasticisers and organo-tin stabilisers for the formulation are given. Many binders are specified, preferably these should not react with the free epoxy groups. (UK)

  2. Direct Detection and Imaging of Low-Energy Electrons with Delta-Doped Charge-Coupled Devices

    Science.gov (United States)

    Nikzad, S.; Yu, Q.; Smith, A. L.; Jones, T. J.; Tombrello, T. A.; Elliott, S. T.

    1998-01-01

    We report the use fo delta-doped charge-coupled devices (CCDs) for direct detection of electrons in the 50-1500 eV energy range. These are the first measurements with a solid state device to detect electrons in this energy range.

  3. Large spin accumulation due to spin-charge coupling across a break-junction

    Science.gov (United States)

    Chen, Shuhan; Zou, Han; Chui, Siu-Tat; Ji, Yi

    2013-03-01

    We investigate large spin signals in break-junction nonlocal spin valves (NLSV). The break-junction is a nanometer-sized vacuum tunneling gap between the spin detector and the nonmagnetic channel, formed by electro-static discharge. The spin signals can be either inverted or non-inverted and the magnitudes are much larger than those of standard NLSV. Spin signals with high percentage values (10% - 0%) have been observed. When the frequency of the a.c. modulation is varied, the absolute magnitudes of signals remain the same although the percentage values change. These observations affirm the nonlocal nature of the measurements and rule out local magnetoresistive effects. Owing to the spin-charge coupling across the break-junction, the spin accumulation in a ferromagnet splits into two terms. One term decays on the charge screening length (0.1 nm) and the other decays on the spin diffusion length (10 nm nm). The magnitude of the former is proportional to the resistance of the junction. Therefore a highly resistive break-junction leads to a large spin accumulation and thereby a large spin signal. The signs of the spin signal are determined by the relationship between spin-dependent conductivities, diffusion constants, and density of states of the ferromagnet. This work was supported by US DOE grant No. DE-FG02-07ER46374.

  4. Spin-charge coupled dynamics driven by a time-dependent magnetization

    Science.gov (United States)

    Tölle, Sebastian; Eckern, Ulrich; Gorini, Cosimo

    2017-03-01

    The spin-charge coupled dynamics in a thin, magnetized metallic system are investigated. The effective driving force acting on the charge carriers is generated by a dynamical magnetic texture, which can be induced, e.g., by a magnetic material in contact with a normal-metal system. We consider a general inversion-asymmetric substrate/normal-metal/magnet structure, which, by specifying the precise nature of each layer, can mimic various experimentally employed setups. Inversion symmetry breaking gives rise to an effective Rashba spin-orbit interaction. We derive general spin-charge kinetic equations which show that such spin-orbit interaction, together with anisotropic Elliott-Yafet spin relaxation, yields significant corrections to the magnetization-induced dynamics. In particular, we present a consistent treatment of the spin density and spin current contributions to the equations of motion, inter alia, identifying a term in the effective force which appears due to a spin current polarized parallel to the magnetization. This "inverse-spin-filter" contribution depends markedly on the parameter which describes the anisotropy in spin relaxation. To further highlight the physical meaning of the different contributions, the spin-pumping configuration of typical experimental setups is analyzed in detail. In the two-dimensional limit the buildup of dc voltage is dominated by the spin-galvanic (inverse Edelstein) effect. A measuring scheme that could isolate this contribution is discussed.

  5. Charge coupled devices for detection of coherent neutrino-nucleus scattering

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez Moroni, Guillermo; Estrada, Juan; Paolini, Eduardo E.; Cancelo, Gustavo; Tiffenberg, Javier; Molina, Jorge

    2015-04-01

    In this article the feasibility of using charge coupled devices (CCD) to detect low-energy neutrinos through their coherent scattering with nuclei is analyzed. The detection of neutrinos through this standard model process has been elusive because of the small energy deposited in such interaction. Typical particle detectors have thresholds of a few keV, and most of the energy deposition expected from coherent scattering is well below this level. The CCD detectors discussed in this paper can operate at a threshold of approximately 30 eV, making them ideal for observing this signal. On a CCD array of 500 g located next to a power nuclear reactor the number of coherent scattering events expected is about 3000 events/year. Our results shows that a detection with a confidence level of 99% can be reached within 16 days of continuous operation; with the current 52 g detector prototype this time lapse extends to five months.

  6. [A capillary blood flow velocity detection system based on linear array charge-coupled devices].

    Science.gov (United States)

    Zhou, Houming; Wang, Ruofeng; Dang, Qi; Yang, Li; Wang, Xiang

    2017-12-01

    In order to detect the flow characteristics of blood samples in the capillary, this paper introduces a blood flow velocity measurement system based on field-programmable gate array (FPGA), linear charge-coupled devices (CCD) and personal computer (PC) software structure. Based on the analysis of the TCD1703C and AD9826 device data sheets, Verilog HDL hardware description language was used to design and simulate the driver. Image signal acquisition and the extraction of the real-time edge information of the blood sample were carried out synchronously in the FPGA. Then a series of discrete displacement were performed in a differential operation to scan each of the blood samples displacement, so that the sample flow rate could be obtained. Finally, the feasibility of the blood flow velocity detection system was verified by simulation and debugging. After drawing the flow velocity curve and analyzing the velocity characteristics, the significance of measuring blood flow velocity is analyzed. The results show that the measurement of the system is less time-consuming and less complex than other flow rate monitoring schemes.

  7. Feasibility study of a lens-coupled charge-coupled device gamma camera

    International Nuclear Information System (INIS)

    Lee, Hakjae; Jung, Youngjun; Kim, Jungmin; Bae, Seungbin; Lee, Kisung; Kang, Jungwon

    2011-01-01

    A charge-coupled device (CCD) is generally used in a digital camera as a light-collecting device such as a photomultiplier tube (PMT). Because of its low sensitivity and very high dark current, CCD have not been popularly used for gamma imaging systems. However, a recent CCD technological breakthrough has improved CCD sensitivity, and the use of a Peltier cooling system can significantly minimize the dark current. In this study, we investigated the feasibility of a prototype CCD gamma camera consisting of a CsI scintillator, optical lenses, and a CCD module. Despite electron-multiplying (EM) CCDs having higher performance, in this study, we built a cost-effective system consisted of low-cost components compared to EMCCDs. Our prototype detector consists of a CsI scintillator, two optical lenses, and a conventional Peltier-cooled CCD. The performance of this detector was evaluated by acquiring the sensitivity, resolution, and the modulation transfer function (MTF). The sensitivity of the prototype detector showed excellent linearity. With a 1 mm-diameter pinhole collimator, the full width at half-maximum (FWHM) of a 1.1 mm Tc-99m line source image was 2.85 mm. These results show that the developed prototype camera is feasible for small animal gamma imaging.

  8. Design and evaluation of a high-performance charge coupled device camera for astronomical imaging

    International Nuclear Information System (INIS)

    Shang, Yuanyuan; Guan, Yong; Zhang, Weigong; Pan, Wei; Liu, Hui; Zhang, Jie

    2009-01-01

    The Space Solar Telescope (SST) is the first Chinese space astronomy mission. This paper introduces the design of a high-performance 2K × 2K charge coupled device (CCD) camera that is an important payload in the Space Solar Telescope. The camera is composed of an analogue system and a digital embedded system. The analogue system is first discussed in detail, including the power and bias voltage supply circuit, power protection unit, CCD clock driver circuit, 16 bit A/D converter and low-noise amplifier circuit. The digital embedded system integrated with an NIOS II soft-core processor serves as the control and data acquisition system of the camera. In addition, research on evaluation methods for CCDs was carried out to evaluate the performance of the TH7899 CCD camera in relation to the requirements of the SST project. We present the evaluation results, including readout noise, linearity, quantum efficiency, dark current, full-well capacity, charge transfer efficiency and gain. The results show that this high-performance CCD camera can satisfy the specifications of the SST project

  9. An image compression method for space multispectral time delay and integration charge coupled device camera

    International Nuclear Information System (INIS)

    Li Jin; Jin Long-Xu; Zhang Ran-Feng

    2013-01-01

    Multispectral time delay and integration charge coupled device (TDICCD) image compression requires a low-complexity encoder because it is usually completed on board where the energy and memory are limited. The Consultative Committee for Space Data Systems (CCSDS) has proposed an image data compression (CCSDS-IDC) algorithm which is so far most widely implemented in hardware. However, it cannot reduce spectral redundancy in multispectral images. In this paper, we propose a low-complexity improved CCSDS-IDC (ICCSDS-IDC)-based distributed source coding (DSC) scheme for multispectral TDICCD image consisting of a few bands. Our scheme is based on an ICCSDS-IDC approach that uses a bit plane extractor to parse the differences in the original image and its wavelet transformed coefficient. The output of bit plane extractor will be encoded by a first order entropy coder. Low-density parity-check-based Slepian—Wolf (SW) coder is adopted to implement the DSC strategy. Experimental results on space multispectral TDICCD images show that the proposed scheme significantly outperforms the CCSDS-IDC-based coder in each band

  10. CCD [charge-coupled device] sensors in synchrotron x-ray detectors

    International Nuclear Information System (INIS)

    Strauss, M.G.; Naday, I.; Sherman, I.S.; Kraimer, M.R.; Westbrook, E.M.; Zaluzec, N.J.

    1987-01-01

    The intense photon flux from advanced synchrotron light sources, such as the 7-GeV synchrotron being designed at Argonne, require integrating-type detectors. Charge-coupled devices (CCDs) are well suited as synchrotron x-ray detectors. When irradiated indirectly via a phosphor followed by reducing optics, diffraction patterns of 100 cm 2 can be imaged on a 2 cm 2 CCD. With a conversion efficiency of ∼1 CCD electron/x-ray photon, a peak saturation capacity of >10 6 x rays can be obtained. A programmable CCD controller operating at a clock frequency of 20 MHz has been developed. The readout rate is 5 x 10 6 pixels/s and the shift rate in the parallel registers is 10 6 lines/s. The test detector was evaluated in two experiments. In protein crystallography diffraction patterns have been obtained from a lysozyme crystal using a conventional rotating anode x-ray generator. Based on these results we expect to obtain at a synchrotron diffraction images at the rate of ∼1 frame/s or a complete 3-dimensional data set from a single crystal in ∼2 min. 16 refs., 16 figs., 2 tabs

  11. Characteristics of charge coupled devices over X-ray spectral band

    Energy Technology Data Exchange (ETDEWEB)

    Mishenskij, V O; Volkov, G S; Zajtsev, V I; Zazhivikhin, V V [Troitsk Institute for Thermonuclear and Innovation Investigations (Russian Federation)

    1997-12-31

    The results of theoretical and experimental investigation of the sensitivity and spatial resolution of charge coupled devices (CCD) influenced by X-ray quanta are reported. Both a calculation model of the interaction process between the X-ray radiation and the CCD-structure and experimental results of investigation of the CCD characteristics are presented. The theoretical model of interaction between X-ray radiation and CCD is suggested. In accordance with the model, the calculations of CCD sensitivity and spatial resolution, depending on the X-ray energy, are performed. The results of comparison of the calculated and experimental data obtained for linear CCD (LCCD) are presented. The CCD has a maximum sensitivity of approx. (1-2.5) . 10{sup 7} V.cm{sup 2}/J for quanta of energies of 0.5-8 keV. The CCD spatial resolution varies from 15-20 {mu}m (CCD gate size) for quanta of energies less then 4 keV and deteriorates up to 150 {mu}m for harder radiation (20-50 keV). CCD usage as space-resolving detectors for high-power installation diagnostics is presented. Other fields of CCD application for X-ray detection are discussed. Advantages of CCD in comparison with the traditional X-ray films is discussed from this point of view. (author). 4 figs., 3 refs.

  12. X-ray intensifying screens

    International Nuclear Information System (INIS)

    Luckey, G.W.; DeBoer, C.D.

    1982-01-01

    An x-ray intensifying screen comprises a support which has a luminescent composition comprising an isotropic phosphor and a polymer having an index of refraction within 0.02 of that of the phosphor over at least 80 percent of its emission spectrum. The support has an index of refraction up to or equal to 0.05 units higher than that of the phosphor and has a reflection optical density of at least 1.7 to light emitted by the phosphor. A preferred luminescent composition comprises Kl:Tl, Rbl:Tl at BaSrFCl:Eu mixed with two monomers such as 1-naphthylmethylmethacrylate, S(1-naphthylmethyl) thioacrylate, 1-bromo-2-naphthylacrylate, and benzyl methacrylate, coated on black anodised Al and polymerised in situ. The ratio of monomers is adjusted to give the desired refractive index. Other phosphors, polymers and supports are specified together with the preparation of the monomers and polymers. (author)

  13. Operating radiographic image intensifier tube

    International Nuclear Information System (INIS)

    Marche, E.; Girard, A.; Barjot, D.; Deon, J.M.; Lacoste, Y.

    1996-01-01

    The intensifier tube operation method involves a voltage supply (U) which is placed across two transistors (Q 1, Q 2) in series. The voltage driver to the photocathode (PC) is the centre point between the two transistors. A switching command is applied to a logic circuit (CL). The logic circuit drives two light emitting diodes (DEL1, DEL2) when a threshold light level is exceeded, each LED triggers an optical switch (TR1, TR2). The switches change the state of the transistors. Switching the upper transistor on and the lower transistor off applies a voltage to the photocathode. Switching off the upper transistor and on the lower transistor blocks the high voltage and sets the photocathode to zero. The advantage of this device is that it involves circuit regulator which is less complex, it has cheaper and more easily implemented transient protection and has reduced sizes. (authors). 10 figs

  14. Angular sensitivity of modeled scientific silicon charge-coupled devices to initial electron direction

    Energy Technology Data Exchange (ETDEWEB)

    Plimley, Brian, E-mail: brian.plimley@gmail.com [Nuclear Engineering Department, University of California, Berkeley, CA (United States); Coffer, Amy; Zhang, Yigong [Nuclear Engineering Department, University of California, Berkeley, CA (United States); Vetter, Kai [Nuclear Engineering Department, University of California, Berkeley, CA (United States); Nuclear Science Division, Lawrence Berkeley National Laboratory, Berkeley, CA (United States)

    2016-08-11

    Previously, scientific silicon charge-coupled devices (CCDs) with 10.5-μm pixel pitch and a thick (650 μm), fully depleted bulk have been used to measure gamma-ray-induced fast electrons and demonstrate electron track Compton imaging. A model of the response of this CCD was also developed and benchmarked to experiment using Monte Carlo electron tracks. We now examine the trade-off in pixel pitch and electronic noise. We extend our CCD response model to different pixel pitch and readout noise per pixel, including pixel pitch of 2.5 μm, 5 μm, 10.5 μm, 20 μm, and 40 μm, and readout noise from 0 eV/pixel to 2 keV/pixel for 10.5 μm pixel pitch. The CCD images generated by this model using simulated electron tracks are processed by our trajectory reconstruction algorithm. The performance of the reconstruction algorithm defines the expected angular sensitivity as a function of electron energy, CCD pixel pitch, and readout noise per pixel. Results show that our existing pixel pitch of 10.5 μm is near optimal for our approach, because smaller pixels add little new information but are subject to greater statistical noise. In addition, we measured the readout noise per pixel for two different device temperatures in order to estimate the effect of temperature on the reconstruction algorithm performance, although the readout is not optimized for higher temperatures. The noise in our device at 240 K increases the FWHM of angular measurement error by no more than a factor of 2, from 26° to 49° FWHM for electrons between 425 keV and 480 keV. Therefore, a CCD could be used for electron-track-based imaging in a Peltier-cooled device.

  15. Quasiclassical methods for spin-charge coupled dynamics in low-dimensional systems

    Energy Technology Data Exchange (ETDEWEB)

    Corini, Cosimo

    2009-06-12

    Spintronics is a new field of study whose broad aim is the manipulation of the spin degrees of freedom in solid state systems. One of its main goals is the realization of devices capable of exploiting, besides the charge, the carriers' - and possibly the nuclei's - spin. The presence of spin-orbit coupling in a system enables the spin and charge degrees of freedom to ''communicate'', a favorable situation if one is to realize such devices. More importantly, it offers the opportunity of doing so by relying solely on electric fields, whereas magnetic fields are otherwise required. Eminent examples of versatile systems with built-in and variously tunable spin-orbit interaction are two-dimensional electron - or hole - gases. The study of spin-charge coupled dynamics in such a context faces a large number of open questions, both of the fundamental and of the more practical type. To tackle the problem we rely on the quasiclassical formalism. This is an approximate quantum-field theoretical formulation with a solid microscopic foundation, perfectly suited for describing phenomena at the mesoscopic scale, and bearing a resemblance to standard Boltzmann theory which makes for physical transparency. Originally born to deal with transport in electron-phonon systems, we first generalize it to the case in which spin-orbit coupling is present, and then move on to apply it to specific situations and phenomena. Among these, to the description of the spin Hall effect and of voltage induced spin polarizations in two-dimensional electron gases under a variety of conditions - stationary or time-dependent, in the presence of magnetic and non-magnetic disorder, in the bulk or in confined geometries -, and to the problem of spin relaxation in narrow wires. (orig.)

  16. Quasiclassical methods for spin-charge coupled dynamics in low-dimensional systems

    International Nuclear Information System (INIS)

    Corini, Cosimo

    2009-01-01

    Spintronics is a new field of study whose broad aim is the manipulation of the spin degrees of freedom in solid state systems. One of its main goals is the realization of devices capable of exploiting, besides the charge, the carriers' - and possibly the nuclei's - spin. The presence of spin-orbit coupling in a system enables the spin and charge degrees of freedom to ''communicate'', a favorable situation if one is to realize such devices. More importantly, it offers the opportunity of doing so by relying solely on electric fields, whereas magnetic fields are otherwise required. Eminent examples of versatile systems with built-in and variously tunable spin-orbit interaction are two-dimensional electron - or hole - gases. The study of spin-charge coupled dynamics in such a context faces a large number of open questions, both of the fundamental and of the more practical type. To tackle the problem we rely on the quasiclassical formalism. This is an approximate quantum-field theoretical formulation with a solid microscopic foundation, perfectly suited for describing phenomena at the mesoscopic scale, and bearing a resemblance to standard Boltzmann theory which makes for physical transparency. Originally born to deal with transport in electron-phonon systems, we first generalize it to the case in which spin-orbit coupling is present, and then move on to apply it to specific situations and phenomena. Among these, to the description of the spin Hall effect and of voltage induced spin polarizations in two-dimensional electron gases under a variety of conditions - stationary or time-dependent, in the presence of magnetic and non-magnetic disorder, in the bulk or in confined geometries -, and to the problem of spin relaxation in narrow wires. (orig.)

  17. Recent progress in color image intensifier

    International Nuclear Information System (INIS)

    Nittoh, K.

    2010-01-01

    A multi-color scintillator based high-sensitive, wide dynamic range and long-life X-ray image intensifier (Ultimage TM ) has been developed. Europium activated Y 2 O 2 S scintillator, emitting red, green and blue wavelength photons of different intensities, is utilized as the output fluorescent screen of the intensifier. By combining this image intensifier with a suitably tuned high sensitive color CCD camera, the sensitivity of the red color component achieved six times higher than that of the conventional image intensifier. Simultaneous emission of a moderate green color and a weak blue color covers different sensitivity regions. This widens the dynamic range by nearly two orders of magnitude. With this image intensifier, it is possible to image complex objects containing various different X-ray transmissions from paper, water or plastic to heavy metals at a time. This color scintillator based image intensifier is widely used in X-ray inspections of various fields. (author)

  18. Lexicon and Description of Sui Adjective Intensifiers

    Directory of Open Access Journals (Sweden)

    James N. Stanford

    2007-01-01

    Full Text Available Sui, an indigenous minority language of southwest China, has an elaborate system of adjective intensification. Adjectives are intensified with word-specific, bound morphemes that usually either rhyme with the base or alliterate with the base. Stanford (2007 notes morpho-phonological patterns that suggest reduplication, rhyme, alliteration, The Emergence of the Unmarked (McCarthy & Prince 1994, Yip 2001, identity avoidance, and “Copy But Don’t Repeat” (Kennard 2004. However, the adjective intensifiers defy a simple, fully predictable explanation in such terms; the intensifier lexicon may be best described as “patterned variety,” a case of lexicalized poetry or a poeticized lexicon. Word formation is guided by general patterns, but each specific intensifier may vary within those overall guidelines. Many adjectives have multiple intensifiers that bear subtle semantic and pragmatic distinctions. The current paper serves as a complement to Stanford (2007 by providing a detailed lexicon of the Sui adjective intensifiers for future reference and further analysis. This lexicon is based on the author’s fieldwork and represents the first detailed account of Sui adjective intensifiers for the wider linguistic community.

  19. X-ray acquisition and electronic digital readout by charge coupled devices

    International Nuclear Information System (INIS)

    Cavailler, C.; Launspach, J.; Mens, A.; Sauneuf, R.

    1985-09-01

    X-ray imaging adapted to laser-matter interaction experiments consists in recording plasma images from its X-ray emission; these phenomena have between 100 ps and some nanoseconds duration. Investigation of the laser-driven plasma may require the formation and the detection of two-dimensional images formed by X-ray microscopes or spectrometers in the soft X-ray range (from about 50 eV to some keV). To reach that purpose, we have developed and tested two opto-electronic chains. The first one is built around a small image converter tube with a soft X-ray photocathode and P20 phosphor screen deposited on a fiber optic plate; the electronic image appearing on the screen is read by a C.C.D. working in the visible spectral range. The second one, designed to work below 100eV is realized with a very thin phosphor screen deposited on the fiber optic input of a visible microchannel image intensifier; the output image is then read by a C.C.D. in the same manner than previously

  20. X-ray image intensifier photography

    International Nuclear Information System (INIS)

    Richter, K.; Angerstein, W.; Steinhardt, L.

    1980-01-01

    The present treatise on X-ray image intensifier photography starts with introductory remarks on the history of X-ray imaging and image intensifiers. In the physical-technological part especially the quality of image and the methods of its measurement are discussed in detail. The relevant equipment such as image intensifier cameras, X-ray television, video recorder and devices of display and evaluation of images are presented as well as problems of radiation doses and radiation protection. Based on 25,000 examinations of the digestive, the biliary and the urinary tract, resp., as well as of the blood vessels the applicability of the X-ray image intensifier photography and its diagnostic value are demonstrated in the medical part of the book

  1. Characteristics of image converters and image intensifiers

    International Nuclear Information System (INIS)

    Gurvich, A.M.; Shamanov, A.A.; Rozenberg, A.M.; Fajnberg, V.S.; Kavtorova, V.P.; Salyuk, L.V.; Yakovleva, F.B.

    1978-01-01

    The characteristics of image converters and image intensifiers, which determine the range of the X-radiation dose rates used and the image quality, are considered. The equations for calculating the requirements to be imposed on the separate intensifier elements from known parameters of other elements with an allowance for the nonlinearity of the television system and the role of fluctuation in the space distribution of X-radiation quanta are given

  2. X-ray image intensifier tube

    International Nuclear Information System (INIS)

    1981-01-01

    An improved real-time x-ray image intensifier tube of the proximity type used for medical x-ray fluoroscopy is described. It is claimed that this intensifier is of sufficient gain and resolution whilst remaining convenient to use and that the design is such that the patient dosage is minimized whilst the x-ray image information content at the scintillator-photocathode screen is maximized. (U.K.)

  3. Impact of measuring electron tracks in high-resolution scientific charge-coupled devices within Compton imaging systems

    International Nuclear Information System (INIS)

    Chivers, D.H.; Coffer, A.; Plimley, B.; Vetter, K.

    2011-01-01

    We have implemented benchmarked models to determine the gain in sensitivity of electron-tracking based Compton imaging relative to conventional Compton imaging by the use of high-resolution scientific charge-coupled devices (CCD). These models are based on the recently demonstrated ability of electron-tracking based Compton imaging by using fully depleted scientific CCDs. Here we evaluate the gain in sensitivity by employing Monte Carlo simulations in combination with advanced charge transport models to calculate two-dimensional charge distributions corresponding to experimentally obtained tracks. In order to reconstruct the angle of the incident γ-ray, a trajectory determination algorithm was used on each track and integrated into a back-projection routine utilizing a geodesic-vertex ray tracing technique. Analysis was performed for incident γ-ray energies of 662 keV and results show an increase in sensitivity consistent with tracking of the Compton electron to approximately ±30 o .

  4. A self triggered intensified Ccd (Stic)

    International Nuclear Information System (INIS)

    Charon, Y.; Laniece, P.; Bendali, M.

    1990-01-01

    We are developing a new device based on the results reported previously of the successfull coincidence detection of β- particles with a high spatial resolution [1]. The novelty of the device consists in triggering an intensified CCD, i.e. a CCD coupled to an image intensifier (II), by an electrical signal collected from the II itself. This is a suitable procedure for detecting with high efficiency and high resolution low light rare events. The trigger pulse is obtained from the secondary electrons produced by multiplication in a double microchannel plate (MCP) and collected on the aluminized layer protecting the phosphor screen in the II. Triggering efficiencies up to 80% has been already achieved

  5. Human water consumption intensifies hydrological drought worldwide

    International Nuclear Information System (INIS)

    Wada, Yoshihide; Van Beek, Ludovicus P H; Wanders, Niko; Bierkens, Marc F P

    2013-01-01

    Over the past 50 years, human water use has more than doubled and affected streamflow over various regions of the world. However, it remains unclear to what degree human water consumption intensifies hydrological drought (the occurrence of anomalously low streamflow). Here, we quantify over the period 1960–2010 the impact of human water consumption on the intensity and frequency of hydrological drought worldwide. The results show that human water consumption substantially reduced local and downstream streamflow over Europe, North America and Asia, and subsequently intensified the magnitude of hydrological droughts by 10–500%, occurring during nation- and continent-wide drought events. Also, human water consumption alone increased global drought frequency by 27 (±6)%. The intensification of drought frequency is most severe over Asia (35 ± 7%), but also substantial over North America (25 ± 6%) and Europe (20 ± 5%). Importantly, the severe drought conditions are driven primarily by human water consumption over many parts of these regions. Irrigation is responsible for the intensification of hydrological droughts over the western and central US, southern Europe and Asia, whereas the impact of industrial and households’ consumption on the intensification is considerably larger over the eastern US and western and central Europe. Our findings reveal that human water consumption is one of the more important mechanisms intensifying hydrological drought, and is likely to remain as a major factor affecting drought intensity and frequency in the coming decades. (letter)

  6. A 5-μm pitch charge-coupled device optimized for resonant inelastic soft X-ray scattering

    Science.gov (United States)

    Andresen, N. C.; Denes, P.; Goldschmidt, A.; Joseph, J.; Karcher, A.; Tindall, C. S.

    2017-08-01

    We have developed a charge-coupled device (CCD) with 5 μm × 45 μm pixels on high-resistivity silicon. The fully depleted 200 μm-thick silicon detector is back-illuminated through a 10 nm-thick in situ doped polysilicon window and is thus highly efficient for soft through >8 keV hard X-rays. The device described here is a 1.5 megapixel CCD with 2496 × 620 pixels. The pixel and camera geometry was optimized for Resonant Inelastic X-ray Scattering (RIXS) and is particularly advantageous for spectrometers with limited arm lengths. In this article, we describe the device architecture, construction and operation, and its performance during tests at the Advance Light Source (ALS) 8.0.1 RIXS beamline. The improved spectroscopic performance, when compared with a current standard commercial camera, is demonstrated with a ˜280 eV (CK) X-ray beam on a graphite sample. Readout noise is typically 3-6 electrons and the point spread function for soft CK X-rays in the 5 μm direction is 4.0 μm ± 0.2 μm. The measured quantum efficiency of the CCD is greater than 75% in the range from 200 eV to 1 keV.

  7. Modulation transfer function and detective quantum efficiency of electron bombarded charge coupled device detector for low energy electrons

    International Nuclear Information System (INIS)

    Horacek, Miroslav

    2005-01-01

    The use of a thinned back-side illuminated charge coupled device chip as two-dimensional sensor working in direct electron bombarded mode at optimum energy of the incident signal electrons is demonstrated and the measurements of the modulation transfer function (MTF) and detective quantum efficiency (DQE) are described. The MTF was measured for energy of electrons 4 keV using an edge projection method and a stripe projection method. The decrease of the MTF for a maximum spatial frequency of 20.8 cycles/mm, corresponding to the pixel size 24x24 μm, is 0.75≅-2.5 dB, and it is approximately the same for both horizontal and vertical directions. DQE was measured using an empty image and the mixing factor method. Empty images were acquired for energies of electrons from 2 to 5 keV and for various doses, ranging from nearly dark image to a nearly saturated one. DQE increases with increasing energy of bombarded electrons and reaches 0.92 for electron energy of 5 keV. For this energy the detector will be used for the angle- and energy-selective detection of signal electrons in the scanning low energy electron microscope

  8. Analysis on the Effect of Sensor Views in Image Reconstruction Produced by Optical Tomography System Using Charge-Coupled Device.

    Science.gov (United States)

    Jamaludin, Juliza; Rahim, Ruzairi Abdul; Fazul Rahiman, Mohd Hafiz; Mohd Rohani, Jemmy

    2018-04-01

    Optical tomography (OPT) is a method to capture a cross-sectional image based on the data obtained by sensors, distributed around the periphery of the analyzed system. This system is based on the measurement of the final light attenuation or absorption of radiation after crossing the measured objects. The number of sensor views will affect the results of image reconstruction, where the high number of sensor views per projection will give a high image quality. This research presents an application of charge-coupled device linear sensor and laser diode in an OPT system. Experiments in detecting solid and transparent objects in crystal clear water were conducted. Two numbers of sensors views, 160 and 320 views are evaluated in this research in reconstructing the images. The image reconstruction algorithms used were filtered images of linear back projection algorithms. Analysis on comparing the simulation and experiments image results shows that, with 320 image views giving less area error than 160 views. This suggests that high image view resulted in the high resolution of image reconstruction.

  9. Short term ionizing radiation impact on charge-coupled devices in radiation environment of high-intensity heavy ion accelerators

    International Nuclear Information System (INIS)

    Belousov, A.; Mustafin, E.; Ensinger, W.

    2012-01-01

    This paper presents a first approach on studies of the results of short term ionizing radiation impact on charge-coupled device (CCD) chips in conditions typical for high-intensity ion accelerator areas. Radiation effects on semiconductor devices are a topical issue for high-intensity accelerator projects. In particular it concerns CCD cameras that are widely used for beam profile monitoring and surveillance in high radiation environment. 65 CCD cameras are going to be installed in the FAIR machines. It is necessary to have good understanding of radiation effects and their contribution to measured signal in CCD chips. A phenomenon of single event upset (SEU) in CCD chips is studied in the following experiment. By SEU in CCD chip we mean an event when an ionizing particle hits the CCD matrix cell and produces electron-hole pairs that are then collected and converted to a signal that is higher than certain level defined by author. Practically, it means that a certain cell will appear as a bright pixel on the resulting image from a chip. (authors)

  10. A 5-μm pitch charge-coupled device optimized for resonant inelastic soft X-ray scattering.

    Science.gov (United States)

    Andresen, N C; Denes, P; Goldschmidt, A; Joseph, J; Karcher, A; Tindall, C S

    2017-08-01

    We have developed a charge-coupled device (CCD) with 5 μm × 45 μm pixels on high-resistivity silicon. The fully depleted 200 μm-thick silicon detector is back-illuminated through a 10 nm-thick in situ doped polysilicon window and is thus highly efficient for soft through >8 keV hard X-rays. The device described here is a 1.5 megapixel CCD with 2496 × 620 pixels. The pixel and camera geometry was optimized for Resonant Inelastic X-ray Scattering (RIXS) and is particularly advantageous for spectrometers with limited arm lengths. In this article, we describe the device architecture, construction and operation, and its performance during tests at the Advance Light Source (ALS) 8.0.1 RIXS beamline. The improved spectroscopic performance, when compared with a current standard commercial camera, is demonstrated with a ∼280 eV (C K ) X-ray beam on a graphite sample. Readout noise is typically 3-6 electrons and the point spread function for soft C K X-rays in the 5 μm direction is 4.0 μm ± 0.2 μm. The measured quantum efficiency of the CCD is greater than 75% in the range from 200 eV to 1 keV.

  11. Recognition and Matching of Clustered Mature Litchi Fruits Using Binocular Charge-Coupled Device (CCD Color Cameras

    Directory of Open Access Journals (Sweden)

    Chenglin Wang

    2017-11-01

    Full Text Available Recognition and matching of litchi fruits are critical steps for litchi harvesting robots to successfully grasp litchi. However, due to the randomness of litchi growth, such as clustered growth with uncertain number of fruits and random occlusion by leaves, branches and other fruits, the recognition and matching of the fruit become a challenge. Therefore, this study firstly defined mature litchi fruit as three clustered categories. Then an approach for recognition and matching of clustered mature litchi fruit was developed based on litchi color images acquired by binocular charge-coupled device (CCD color cameras. The approach mainly included three steps: (1 calibration of binocular color cameras and litchi image acquisition; (2 segmentation of litchi fruits using four kinds of supervised classifiers, and recognition of the pre-defined categories of clustered litchi fruit using a pixel threshold method; and (3 matching the recognized clustered fruit using a geometric center-based matching method. The experimental results showed that the proposed recognition method could be robust against the influences of varying illumination and occlusion conditions, and precisely recognize clustered litchi fruit. In the tested 432 clustered litchi fruits, the highest and lowest average recognition rates were 94.17% and 92.00% under sunny back-lighting and partial occlusion, and sunny front-lighting and non-occlusion conditions, respectively. From 50 pairs of tested images, the highest and lowest matching success rates were 97.37% and 91.96% under sunny back-lighting and non-occlusion, and sunny front-lighting and partial occlusion conditions, respectively.

  12. Intensified coastal development behind nourished beaches

    Science.gov (United States)

    Armstrong, Scott; Lazarus, Eli; Limber, Patrick; Goldstein, Evan; Thorpe, Curtis; Ballinger, Rhoda

    2016-04-01

    Population density, housing development, and property values in coastal counties along the U.S. Atlantic and Gulf Coasts continue to rise despite increasing hazard from storm impacts. Since the 1970s, beach nourishment, which involves importing sand to deliberately widen an eroding beach, has been the main strategy in the U.S. for protecting coastal properties from erosion and flooding hazards. Paradoxically, investment in hazard protection may intensify development. Here, we examine the housing stock of all existing shorefront single-family homes in Florida - a microcosm of U.S. coastal hazards and development - to quantitatively compare development in nourishing and non-nourishing towns. We find that nourishing towns now account for more than half of Florida's coastline, and that houses in nourishing towns are larger and more numerous. Even as the mean size of single-family homes nationwide has grown steadily since 1970, Florida's shorefront stock has exceeded the national average by 34%, and in nourishing towns by 45%. This emergent disparity between nourishing and non-nourishing towns in Florida demonstrates a pattern of intensifying coastal risk, and is likely representative of a dominant trend in coastal development more generally. These data lend empirical support to the hypothesis that US coastal development and hazard mitigation through beach nourishment have become dynamically coupled.

  13. Improving radiation hardness in space-based Charge-Coupled Devices through the narrowing of the charge transfer channel

    Science.gov (United States)

    Hall, D. J.; Skottfelt, J.; Soman, M. R.; Bush, N.; Holland, A.

    2017-12-01

    Charge-Coupled Devices (CCDs) have been the detector of choice for imaging and spectroscopy in space missions for several decades, such as those being used for the Euclid VIS instrument and baselined for the SMILE SXI. Despite the many positive properties of CCDs, such as the high quantum efficiency and low noise, when used in a space environment the detectors suffer damage from the often-harsh radiation environment. High energy particles can create defects in the silicon lattice which act to trap the signal electrons being transferred through the device, reducing the signal measured and effectively increasing the noise. We can reduce the impact of radiation on the devices through four key methods: increased radiation shielding, device design considerations, optimisation of operating conditions, and image correction. Here, we concentrate on device design operations, investigating the impact of narrowing the charge-transfer channel in the device with the aim of minimising the impact of traps during readout. Previous studies for the Euclid VIS instrument considered two devices, the e2v CCD204 and CCD273, the serial register of the former having a 50 μm channel and the latter having a 20 μm channel. The reduction in channel width was previously modelled to give an approximate 1.6× reduction in charge storage volume, verified experimentally to have a reduction in charge transfer inefficiency of 1.7×. The methods used to simulate the reduction approximated the charge cloud to a sharp-edged volume within which the probability of capture by traps was 100%. For high signals and slow readout speeds, this is a reasonable approximation. However, for low signals and higher readout speeds, the approximation falls short. Here we discuss a new method of simulating and calculating charge storage variations with device design changes, considering the absolute probability of capture across the pixel, bringing validity to all signal sizes and readout speeds. Using this method, we

  14. Upwards Intensifiers in the English, German and Croatian Language

    Directory of Open Access Journals (Sweden)

    Anita Pavić Pintarić

    2014-12-01

    Full Text Available This paper investigates the upwards intensifiers (adverbs of intensifying in the English, German and Croatian language. Intensity as an important human cognitive category, and language expressivity is differently treated in grammars and dictionaries of all three languages, especially with respect to different degrees of intensity. In this paper we argue that it is possible to model a typology of upwards adverb intensifiers in the three languages, according to their morphosyntactic and semantic aspects. When it comes to intensifiers, it is necessary to describe which collocates are modified by intensifiers and which semantic fields the collocates belong to. The results of the corpus analysis based on Harry Potter novels show that all the three languages express the category of the upwards intensity in the same way: the number of intensifiers is similar, the collocates mostly belong to the same semantic fields and word classes, they have similar syntactic functions.

  15. Duodenal fat intensifies the perception of heartburn

    Science.gov (United States)

    Meyer, J; Lembo, A; Elashoff, J; Fass, R; Mayer, E

    2001-01-01

    BACKGROUND—Patients with gastro-oesophageal reflux disease (GORD) frequently report that meals high in fat worsen heartburn. Nevertheless, studies to determine whether high fat meals promote gastro-oesophageal reflux have produced conflicting and equivocal conclusions.
PATIENTS AND METHODS—To determine, alternatively, whether fat in the small intestinal lumen intensifies the perception of heartburn, we studied 11 patients with typical heartburn from GORD. After being placed on omeprazole to suppress endogenous acid, these fasting subjects underwent oesophageal perfusions with graded doses of HCl at pH values of 1.0, 1.5, 2.0, and 2.5. Oesophageal perfusions were conducted while the duodenum was perfused with saline (control) and again with fat at 8 g/h.
RESULTS—Time to onset, intensity, and severity of heartburn varied with dose of oesophageal acid (pheartburn significantly (pheartburn.


Keywords: gastro-oesophageal reflux disease; heartburn; perception; fat PMID:11600463

  16. CCD[charge-coupled device]-based synchrotron x-ray detector for protein crystallography: Performance projected from an experiment

    International Nuclear Information System (INIS)

    Strauss, M.G.; Naday, I.; Sherman, I.S.; Kraimer, M.R.; Westbrook, E.M.

    1986-01-01

    The intense x radiation from a synchrotron source could, with a suitable detector, provide a complete set of diffraction images from a protein crystal before the crystal is damaged by radiation (2 to 3 min). An area detector consisting of a 40 mm dia. x-ray fluorescing phosphor, coupled with an image intensifier and lens to a CCD image sensor, was developed to determine the effectiveness of such a detector in protein crystallography. The detector was used in an experiment with a rotating anode x-ray generator. Diffraction patterns from a lysozyme crystal obtained with this detector are compared to those obtained with film. The two images appear to be virtually identical. The flux of 10 4 x-ray photons/s was observed on the detector at the rotating anode generator. At the 6-GeV synchrotron being designed at Argonne, the flux on an 80 x 80 mm 2 detector is expected to be >10 9 photons/s. The projected design of such a synchrotron detector shows that a diffraction-peak count >10 6 could be obtained in ∼0.5 s. With an additional ∼0.5 s readout time of a 512 x 512 pixel CCD, the data acquisition time per frame would be ∼1 s so that ninety 1 0 diffraction images could be obtained, with approximately 1% precision, in less than 3 min

  17. New feature of the neutron color image intensifier

    Science.gov (United States)

    Nittoh, Koichi; Konagai, Chikara; Noji, Takashi; Miyabe, Keisuke

    2009-06-01

    We developed prototype neutron color image intensifiers with high-sensitivity, wide dynamic range and long-life characteristics. In the prototype intensifier (Gd-Type 1), a terbium-activated Gd 2O 2S is used as the input-screen phosphor. In the upgraded model (Gd-Type 2), Gd 2O 3 and CsI:Na are vacuum deposited to form the phosphor layer, which improved the sensitivity and the spatial uniformity. A europium-activated Y 2O 2S multi-color scintillator, emitting red, green and blue photons with different intensities, is utilized as the output screen of the intensifier. By combining this image intensifier with a suitably tuned high-sensitive color CCD camera, higher sensitivity and wider dynamic range could be simultaneously attained than that of the conventional P20-phosphor-type image intensifier. The results of experiments at the JRR-3M neutron radiography irradiation port (flux: 1.5×10 8 n/cm 2/s) showed that these neutron color image intensifiers can clearly image dynamic phenomena with a 30 frame/s video picture. It is expected that the color image intensifier will be used as a new two-dimensional neutron sensor in new application fields.

  18. New feature of the neutron color image intensifier

    International Nuclear Information System (INIS)

    Nittoh, Koichi; Konagai, Chikara; Noji, Takashi; Miyabe, Keisuke

    2009-01-01

    We developed prototype neutron color image intensifiers with high-sensitivity, wide dynamic range and long-life characteristics. In the prototype intensifier (Gd-Type 1), a terbium-activated Gd 2 O 2 S is used as the input-screen phosphor. In the upgraded model (Gd-Type 2), Gd 2 O 3 and CsI:Na are vacuum deposited to form the phosphor layer, which improved the sensitivity and the spatial uniformity. A europium-activated Y 2 O 2 S multi-color scintillator, emitting red, green and blue photons with different intensities, is utilized as the output screen of the intensifier. By combining this image intensifier with a suitably tuned high-sensitive color CCD camera, higher sensitivity and wider dynamic range could be simultaneously attained than that of the conventional P20-phosphor-type image intensifier. The results of experiments at the JRR-3M neutron radiography irradiation port (flux: 1.5x10 8 n/cm 2 /s) showed that these neutron color image intensifiers can clearly image dynamic phenomena with a 30 frame/s video picture. It is expected that the color image intensifier will be used as a new two-dimensional neutron sensor in new application fields.

  19. The construction and evaluation of a prototype system for an image intensifier-based volume computed tomography imager

    International Nuclear Information System (INIS)

    Ning, R.

    1989-01-01

    A volumetric reconstruction of a three-dimensional (3-D) object has been at the forefront of exploration in medical applications for a long time. To achieve this goal, a prototype system for an image intensifier(II)-based volume computed tomography (CT) imager has been constructed. This research has been concerned with constructing and evaluating such a prototype system by phantom studies. The prototype system consists of a fixed x-ray tube, a specially designed aluminum filter that will reduce the dynamic range of projection data, an antiscatter grid, a conventional image intensifier optically coupled to a charge-coupled device (CCC) camera, a computer controlled turntable on which phantoms are placed, a digital computer including an A/D converter and a graphic station that displays the reconstructed images. In this study, three different phantoms were used: a vascular phantom, a resolution phantom and a Humanoid reg-sign chest phantom. The direct 3-D reconstruction from the projections was performed using a cone beam algorithm and vascular reconstruction algorithms. The image performance of the system for the direct 3-D reconstruction was evaluated. The spatial resolution limits of the system were estimated through observing the reconstructed images of the resolution phantom. By observing the images reconstructed from the projections, it can be determined that the image performance of the prototype system for a direct 3-D reconstruction is reasonably good and that the vascular reconstruction algorithms work very well. The results also indicate that the 3-D reconstructions obtained with the 11-based volume CT imager have nearly equally good resolution in x, y and z directions and are superior to a conventional CT in the resolution of the z direction

  20. Properties of image intensifier-related halation artifact in limited volume cone-beam CT for dental use

    International Nuclear Information System (INIS)

    Hirukawa, Akiko; Okumura, Shinji; Matsuo, Ayae; Yokoi, Midori; Gotoh, Kenichi; Katsumata, Akitoshi; Naitoh, Munetaka; Ariji, Eiichiro

    2006-01-01

    Artifacts due to halation from an image intensifier (I.I.)/charge coupled device (CCD) system appear on limited-volume cone-beam computed tomography (CBCT). Regarding anterior tooth imaging, properties of this artifact in the geometrical relationships between field of view (FOV) and objective jaw region were studied. A water-filled plastic cylinder was used as a phantom of the head. A test object was constructed as a bone-equivalent phantom to be imaged. The test object was set in the phantom at positions corresponding to the anterior tooth arch. Position of the test object was shifted to simulate individual variations in the thickness of the labial soft tissue. Limited-volume CBCT images were acquired using a 3DX system in the various offset FOV position. The affection of an artifact was evaluated by the size of the object's image. The position of the test object in the phantom, i.e. the thickness of the labial soft tissue contributes to the intensity of artifact. However, even when the labial soft tissue was thick, affection from artifact was prominent when the FOV was set so that the image of the test object was depicted near the margin of FOV. (author)

  1. Fluorescent intensifying screens: contribution of secondary X-rays

    International Nuclear Information System (INIS)

    Barroso, R.C.; Goncalves, O.D.; Eichler, J.; Lopes, R.T.; Cardoso, S.C.

    1996-01-01

    The counting rate and angular distribution of secondary X-rays produced by fluorescent intensifying screens are studied. A source of 241 Am - gamma radiation of 59.54 keV - is used. Fluorescent intensifying screens reduce the radiation dose in radiology since they produce visible light which increases the efficiency of the film. In addition, secondary X-rays arise due to the photoelectric effect, elastic (Rayleigh) and inelastic (Compton) scattering

  2. Pengaruh Jenis Lembar Penguat (Intensifying Screen) Terhadap Densitas Radiografi

    OpenAIRE

    Nasrullah

    2007-01-01

    good ABSTRACT As done research on the influence of type to the density radiography with the objective to define radiography value third-density intensifying screen brand green emitting variation factors exposure and Focus Film Distance is different. Influence of type of intensifying screen to the density radiography is obtained through measurements of the value of radiography density using the densitometer with object stepwedge. The results of this research show that the average dens...

  3. Ground-based Fabry-Perot interferometry of the terrestrial nightglow with a bare charge-coupled device; Remote field site deployment

    International Nuclear Information System (INIS)

    Niciejewski, R.; Killeen, T.L.; Turnbull, M.

    1994-01-01

    The application of Fabry-Perot interferometers (FPIs) to the study of upper atmosphere thermodynamics has largely been restricted by the very low light levels in the terrestrial airglow as well as the limited range in wavelength of photomultiplier tube (PMT) technology. During the past decade, the development of the scientific grade charge-coupled device (CCD) has progressed to the stage in which the detector has become the logical replacement for the PMT. Small fast microcomputers have made it possible to ''upgrade'' the remote field sites which bare CCDs and not only retain the previous capabilities of the existing FPIs but expand the data coverage in both temporal and wavelength domains. The problems encountered and the solutions applied to the deployment of a bare CCD, with data acquisition and image reduction techniques, are discussed. Sample geophysical data determined from the FPI fringe profiles are shown for stations at Peach Mountain, Michigan, and Watson Lake, Yukon Territory

  4. Image Information Obtained Using a Charge-Coupled Device (CCD) Camera During an Immersion Liquid Evaporation Process for Measuring the Refractive Index of Solid Particles.

    Science.gov (United States)

    Niskanen, Ilpo; Sutinen, Veijo; Thungström, Göran; Räty, Jukka

    2018-06-01

    The refractive index is a fundamental physical property of a medium, which can be used for the identification and purity issues of all media. Here we describe a refractive index measurement technique to determine simultaneously the refractive index of different solid particles by monitoring the transmittance of light from a suspension using a charge-coupled device (CCD) camera. An important feature of the measurement is the liquid evaporation process for the refractive index matching of the solid particle and the immersion liquid; this was realized by using a pair of volatile and non-volatile immersion liquids. In this study, refractive indices of calcium fluoride (CaF 2 ) and barium fluoride (BaF 2 ) were determined using the proposed method.

  5. Imaging with organic indicators and high-speed charge-coupled device cameras in neurons: some applications where these classic techniques have advantages.

    Science.gov (United States)

    Ross, William N; Miyazaki, Kenichi; Popovic, Marko A; Zecevic, Dejan

    2015-04-01

    Dynamic calcium and voltage imaging is a major tool in modern cellular neuroscience. Since the beginning of their use over 40 years ago, there have been major improvements in indicators, microscopes, imaging systems, and computers. While cutting edge research has trended toward the use of genetically encoded calcium or voltage indicators, two-photon microscopes, and in vivo preparations, it is worth noting that some questions still may be best approached using more classical methodologies and preparations. In this review, we highlight a few examples in neurons where the combination of charge-coupled device (CCD) imaging and classical organic indicators has revealed information that has so far been more informative than results using the more modern systems. These experiments take advantage of the high frame rates, sensitivity, and spatial integration of the best CCD cameras. These cameras can respond to the faster kinetics of organic voltage and calcium indicators, which closely reflect the fast dynamics of the underlying cellular events.

  6. Growth of a delta-doped silicon layer by molecular beam epitaxy on a charge-coupled device for reflection-limited ultraviolet quantum efficiency

    Science.gov (United States)

    Hoenk, Michael E.; Grunthaner, Paula J.; Grunthaner, Frank J.; Terhune, R. W.; Fattahi, Masoud; Tseng, Hsin-Fu

    1992-01-01

    Low-temperature silicon molecular beam epitaxy is used to grow a delta-doped silicon layer on a fully processed charge-coupled device (CCD). The measured quantum efficiency of the delta-doped backside-thinned CCD is in agreement with the reflection limit for light incident on the back surface in the spectral range of 260-600 nm. The 2.5 nm silicon layer, grown at 450 C, contained a boron delta-layer with surface density of about 2 x 10 exp 14/sq cm. Passivation of the surface was done by steam oxidation of a nominally undoped 1.5 nm Si cap layer. The UV quantum efficiency was found to be uniform and stable with respect to thermal cycling and illumination conditions.

  7. Panel type X-ray image intensifier tube

    International Nuclear Information System (INIS)

    Wang, S.P.

    1977-01-01

    A panel shaped, proximity type, X-ray image intensifier tube for medical X-ray diagnostic is disclosed. It has all linear components and yet a high brightness gain, in the range of 500 to 20,000 cd-sec/m 2 -R, the tube being comprised of a rugged metallic tube envelope, an inwardly concave metallic input window of full size output display screen, an alkaline-halide scintillator photocathode screen suspended on insulators within the envelope and in between the input window and the output screen, and a high Z glass output window to reduce X-ray backscatter inside and outside of the tube. An X-ray sensitive photographic camera for medical diagnostic use is also disclosed which includes an X-ray sensitive image intensifier means of the proximity type and a reduction type optical system having an effective foral length in excess of 100mm for focusing the emage generated on the output display screen of the image intensifier tube onto a small size but directly viewable photographic film. The parameters of the image intensifier, the optics and the film are specified and linked to each other in a manner which maximizes the image quality for a camera system of this type and at the same time restricts the system speed of the camera to a range of 500 to 5,000 R -1 for the film to achieve a net density of 1.0. (Auth.)

  8. Dysphagia screening and intensified oral hygiene reduce pneumonia after stroke

    DEFF Research Database (Denmark)

    Sørensen, Rikke Terp; Rasmussen, Rune Skovgaard; Overgaard, Karsten

    2013-01-01

    Dysphagia occurs in approximately 51%-78% of patients with acute stroke. The incidence of pneumonia caused by aspiration in dysphagic patients increases both mortality and the need for hospitalization. The aim of this study was to investigate whether the incidence of aspiration pneumonia could...... be reduced in such patients by an early screening for dysphagia and intensified oral hygiene....

  9. The image intensifier in oral and maxillofacial surgery

    International Nuclear Information System (INIS)

    Gans, B.J.; Kallal, R.H.; Helgerson, A.C.; Verona, S.R.

    1982-01-01

    The mobile image intensifier has been found useful in the removal of foreign bodies from both intraoral and extraoral sites. The safety of the machine has been verified, and a technique for its application is described. Additional uses for the machine are stated

  10. Intensified multifactorial intervention and cardiovascular outcome in type 2 diabetes

    DEFF Research Database (Denmark)

    Pedersen, Oluf; Gaede, Peter

    2003-01-01

    We recently published the results of the Steno-2 study, which evaluated the benefits of intensified integrated behavior modification and targeted polypharmacy. The results provide abundant evidence that an ambitious treatment strategy is superior to a conventional one. The study involved 160 high...

  11. Emulsification in novel ultrasonic cavitation intensifying bag reactors

    NARCIS (Netherlands)

    Zwieten, van Ralph; Verhaagen, Bram; Schroën, Karin; Fernández Rivas, David

    2017-01-01

    Cavitation Intensifying Bags (CIBs), a novel reactor type for use with ultrasound, have been recently proposed as a scaled-up microreactor with increased energy efficiencies. We now report on the use of the CIBs for the preparation of emulsions out of hexadecane and an SDS aqueous solution. The

  12. Using Brief Experimental Analysis to Intensify Tier 3 Reading Interventions

    Science.gov (United States)

    Coolong-Chaffin, Melissa; Wagner, Dana

    2015-01-01

    As implementation of multi-tiered systems of support becomes common practice across the nation, practitioners continue to need strategies for intensifying interventions and supports for the subset of students who fail to make adequate progress despite strong programs at Tiers 1 and 2. Experts recommend making several changes to the structure and…

  13. Real-time two-dimensional imaging of potassium ion distribution using an ion semiconductor sensor with charged coupled device technology.

    Science.gov (United States)

    Hattori, Toshiaki; Masaki, Yoshitomo; Atsumi, Kazuya; Kato, Ryo; Sawada, Kazuaki

    2010-01-01

    Two-dimensional real-time observation of potassium ion distributions was achieved using an ion imaging device based on charge-coupled device (CCD) and metal-oxide semiconductor technologies, and an ion selective membrane. The CCD potassium ion image sensor was equipped with an array of 32 × 32 pixels (1024 pixels). It could record five frames per second with an area of 4.16 × 4.16 mm(2). Potassium ion images were produced instantly. The leaching of potassium ion from a 3.3 M KCl Ag/AgCl reference electrode was dynamically monitored in aqueous solution. The potassium ion selective membrane on the semiconductor consisted of plasticized poly(vinyl chloride) (PVC) with bis(benzo-15-crown-5). The addition of a polyhedral oligomeric silsesquioxane to the plasticized PVC membrane greatly improved adhesion of the membrane onto Si(3)N(4) of the semiconductor surface, and the potential response was stabilized. The potential response was linear from 10(-2) to 10(-5) M logarithmic concentration of potassium ion. The selectivity coefficients were K(K(+),Li(+))(pot) = 10(-2.85), K(K(+),Na(+))(pot) = 10(-2.30), K(K(+),Rb(+))(pot) =10(-1.16), and K(K(+),Cs(+))(pot) = 10(-2.05).

  14. Diagnostic Accuracy of Charge-coupled Device Sensor and Photostimulable Phosphor Plate Receptor in the Detection of External Root Resorption In Vitro

    Directory of Open Access Journals (Sweden)

    Shirin Sakhdari

    2015-03-01

    Full Text Available Background and aims. Early diagnosis of external root resorption is important for accurate treatment. The purpose of this study was to compare the efficacy of a charge-coupled device (CCD sensor and a photostimulable phosphor (PSP plate receptor in the diagnosis of artificial external root resorption. Materials and methods. In this diagnostic in-vitro study, 40 maxillary incisors were mounted in a segment of dry bone and preliminary radiographs were obtained using CCD and PSP sensors. Artificial resorption cavities were produced on the middle-third in half of the samples and on the cervical-third in the other half on the buccal root surfaces. Radiographs were repeated and images were evaluated. Data were statistically analyzed using chi-square and diagnostic tests. Results. There were no significant differences between the two sensors in the sensitivity (p=0.08 and 0.06 and specificity (p=0.13 for the diagnosis of resorption in both root areas. The overall accuracy of CCD was higher than PSP sensor; how-ever, the difference was not statistically significance (p>0.05. Conclusion. CCD and PSP sensors chosen for the present study produced similar results in diagnosing simulated external root resorption.

  15. A new method for polychromatic X-ray μLaue diffraction on a Cu pillar using an energy-dispersive pn-junction charge-coupled device

    Energy Technology Data Exchange (ETDEWEB)

    Abboud, A.; Send, S.; Pashniak, N.; Pietsch, U. [Department of Physics, University of Siegen, Siegen 57072 (Germany); Kirchlechner, C. [Max-Planck-Institut für Eisenforschung GmbH, Düsseldorf 40237 (Germany); Montanuniversität Leoben, Leoben 8700 (Austria); Micha, J. S.; Ulrich, O. [CEA-Grenoble/DRFMC/SprAM, 17 rue des Martyrs, Grenoble Cedex 9, F-38054 (France); Strüder, L. [PNSensor GmbH, Munich 80803 (Germany); Keckes, J. [Montanuniversität Leoben, Leoben 8700 (Austria); Material Center Leoben Forschungs GmbH, Leoben 8700 (Austria)

    2014-11-15

    μLaue diffraction with a polychromatic X-ray beam can be used to measure strain fields and crystal orientations of micro crystals. The hydrostatic strain tensor can be obtained once the energy profile of the reflections is measured. However, this remains a challenge both on the time scale and reproducibility of the beam position on the sample. In this review, we present a new approach to obtain the spatial and energy profiles of Laue spots by using a pn-junction charge-coupled device, an energy-dispersive area detector providing 3D resolution of incident X-rays. The morphology and energetic structure of various Bragg peaks from a single crystalline Cu micro-cantilever used as a test system were simultaneously acquired. The method facilitates the determination of the Laue spots’ energy spectra without filtering the white X-ray beam. The synchrotron experiment was performed at the BM32 beamline of ESRF using polychromatic X-rays in the energy range between 5 and 25 keV and a beam size of 0.5 μm × 0.5 μm. The feasibility test on the well known system demonstrates the capabilities of the approach and introduces the “3D detector method” as a promising tool for material investigations to separate bending and strain for technical materials.

  16. Short and long term ionizing radiation effects on charge-coupled devices in radiation environment of high-intensity heavy ion accelerators

    International Nuclear Information System (INIS)

    Belousov, A; Mustafin, E; Ensinger, W

    2012-01-01

    Radiation effects on semiconductor devices is a topical issue for high-intensity accelerator projects. In particular it concerns Charge-Coupled Device (CCD) cameras, which are widely used for beam profile monitoring and surveillance in high radiation environment. One should have a clear idea of short and long term radiation effects on such devices. To study these effects, a CCD camera was placed in positions less than half meter away from beam loss point. Primary heavy ion beam of 0.95GeV/n Uranium was dumped into a thick aluminium target creating high fluences of secondary particles (e.g., gammas, neutrons, protons). Effects of these particles on CCD camera were scored with LabView based acquisition software. Monte Carlo calculations with FLUKA code were performed to obtain fluence distributions for different particles and make relevant comparisons. Long term total ionising dose effects are represented by dark current increase, which was scored throughout experiment. Instant radiation effects are represented by creation of charge in CCD cells by ionising particles. Relation of this charge to beam intensity was obtained for different camera positions and fluences within 5 orders of magnitude ranges. With high intensities this charge is so high that it may dramatically influence data obtained from CCD camera used in high radiation environment. The linearity of described above relation confirms linear response of CCD to ionizing radiation. It gives an opportunity to find a new application to CCD cameras as beam loss monitors (BLM).

  17. Breath-hold monitoring and visual feedback for radiotherapy using a charge-coupled device camera and a head-mounted display. System development and feasibility

    International Nuclear Information System (INIS)

    Yoshitake, Tadamasa; Nakamura, Katsumasa; Shioyama, Yoshiyuki

    2008-01-01

    The aim of this study was to present the technical aspects of the breath-hold technique with respiratory monitoring and visual feedback and to evaluate the feasibility of this system in healthy volunteers. To monitor respiration, the vertical position of the fiducial marker placed on the patient's abdomen was tracked by a machine vision system with a charge-coupled device camera. A monocular head-mounted display was used to provide the patient with visual feedback about the breathing trace. Five healthy male volunteers were enrolled in this study. They held their breath at the end-inspiration and the end-expiration phases. They performed five repetitions of the same type of 15-s breath-holds with and without a head-mounted display, respectively. A standard deviation of five mean positions of the fiducial marker during a 15-s breath-hold in each breath-hold type was used as the reproducibility value of breath-hold. All five volunteers well tolerated the breath-hold maneuver. For the inspiration breath-hold, the standard deviations with and without visual feedback were 1.74 mm and 0.84 mm, respectively (P=0.20). For the expiration breath-hold, the standard deviations with and without visual feedback were 0.63 mm and 0.96 mm, respectively (P=0.025). Our newly developed system might help the patient achieve improved breath-hold reproducibility. (author)

  18. Surveying with Charge Coupled Devices

    Science.gov (United States)

    1991-10-01

    100 secs over the 1.4 cm2 active area of the CCD. The rate is consistent with the incident flux of cosmic - ray muons at the Earth’s surface . A small...cometesimals, and various types of asteroids. In the process, we gained experience with cosmic rays and artifacts in CCD observations. Each of these...experience with CCD observing in any case (see Sec. 1), we undertook various studies that will be described in Secs. 4-8. 4. Gamma Rays , Cosmic Rays

  19. Dynamics analysis of extraction of manganese intensified by electric field

    Science.gov (United States)

    Ma, Wenrui; Tao, Changyuan; Li, Huizhan; Liu, Zuohua; Liu, Renlong

    2018-06-01

    In this study, a process reinforcement technology for leaching process of pyrolusite was developed. The electric field was introduced to decrease reaction temperature and improve the leaching rate of pyrolusite. The mechanisms of electric field intensifying leaching process of pyrolusite were investigated through X-ray diffraction (XRD), and Brunauer Emmett Teller (BET) in detail. The results showed that the electric field could decrease obviously the apparent activation energy of leaching process of pyrolusite. The apparent activation energy of the leaching of pyrolusite intensified by electric field was calculated to be 53.76 kJ.mol-1. In addition, the leaching efficiency of manganese was effectively increased by 10% to 20% than that without electric field under the same conditions. This was because that the electron conduit between Fe (II)/Fe (III) and pyrite was dredged effectively by electric field.

  20. Digital image intensifier radiography: A new diagnostic procedure in traumatology?

    International Nuclear Information System (INIS)

    Schmidt, C.; Deininger, H.K.; Staedtische Kliniken Darmstadt

    1990-01-01

    Digital image intensifier radiography visualises all traumatological changes of clinical relevance and can therefore be used in traumatology. However, the quality of conventional radiographs cannot be attained as yet. Radiation exposure is markedly reduced, and radiographs are obtained directly after exposure, so that this is an extremely rapid radiographic procedure. Images can be quickly transmitted by video cable to the relevant departments and working places. (orig.) [de

  1. The role of heat pipes in intensified unit operations

    International Nuclear Information System (INIS)

    Reay, David; Harvey, Adam

    2013-01-01

    Heat pipes are heat transfer devices that rely, most commonly, on the evaporation and condensation of a working fluid contained within them, with passive pumping of the condensate back to the evaporator. They are sometimes referred to as ‘thermal superconductors’ because of their exceptionally high effective thermal conductivity (substantially higher than any metal). This, together with several other characteristics make them attractive to a range of intensified unit operations, particularly reactors. The majority of modern computers deploy heat pipes for cooling of the CPU. The application areas of heat pipes come within a number of broad groups, each of which describes a property of the heat pipe. The ones particularly relevant to chemical reactors are: i. Separation of heat source and sink. ii. Temperature flattening, or isothermalisation. iii. Temperature control. Chemical reactors, as a heat pipe application area, highlight the benefits of the heat pipe based on isothermalisation/temperature flattening device and on being a highly effective heat transfer unit. Temperature control, done passively, is also of relevance. Heat pipe technology offers a number of potential benefits to reactor performance and operation. The aim of increased yield of high purity, high added value chemicals means less waste and higher profitability. Other intensified unit operations, such as those employing sorption processes, can also profit from heat pipe technology. This paper describes several variants of heat pipe and the opportunities for their use in intensified plant, and will give some current examples. -- Highlights: ► Heat pipes – thermal superconductors – can lead to improved chemical reactor performance. ► Isothermalisation within a reactor vessel is an ideal application. ► The variable conductance heat pipe can control reaction temperatures within close limits. ► Heat pipes can be beneficial in intensified reactors

  2. Multiple event 2D image intensifier scintillation detector

    International Nuclear Information System (INIS)

    Thieberger, P.; Wegner, H.E.; Lee, R.C.

    1981-01-01

    An image intensifier scintillation detector has been developed for the simultaneous detection of multiple light or heavy ions down to very low energies. The relative X-Y positions of each ion are read out by digitization of a television image of the light amplified scintillations. The maximum data rate is limited by the present television scan speed to 15 multiple events per second and to about one event second by the microcomputer presently used to store and process the data. (orig.)

  3. A unique charge-coupled device/xenon arc lamp based imaging system for the accurate detection and quantitation of multicolour fluorescence.

    Science.gov (United States)

    Spibey, C A; Jackson, P; Herick, K

    2001-03-01

    In recent years the use of fluorescent dyes in biological applications has dramatically increased. The continual improvement in the capabilities of these fluorescent dyes demands increasingly sensitive detection systems that provide accurate quantitation over a wide linear dynamic range. In the field of proteomics, the detection, quantitation and identification of very low abundance proteins are of extreme importance in understanding cellular processes. Therefore, the instrumentation used to acquire an image of such samples, for spot picking and identification by mass spectrometry, must be sensitive enough to be able, not only, to maximise the sensitivity and dynamic range of the staining dyes but, as importantly, adapt to the ever changing portfolio of fluorescent dyes as they become available. Just as the available fluorescent probes are improving and evolving so are the users application requirements. Therefore, the instrumentation chosen must be flexible to address and adapt to those changing needs. As a result, a highly competitive market for the supply and production of such dyes and the instrumentation for their detection and quantitation have emerged. The instrumentation currently available is based on either laser/photomultiplier tube (PMT) scanning or lamp/charge-coupled device (CCD) based mechanisms. This review briefly discusses the advantages and disadvantages of both System types for fluorescence imaging, gives a technical overview of CCD technology and describes in detail a unique xenon/are lamp CCD based instrument, from PerkinElmer Life Sciences. The Wallac-1442 ARTHUR is unique in its ability to scan both large areas at high resolution and give accurate selectable excitation over the whole of the UV/visible range. It operates by filtering both the excitation and emission wavelengths, providing optimal and accurate measurement and quantitation of virtually any available dye and allows excellent spectral resolution between different fluorophores

  4. Achieving interlocking nails without using an image intensifier.

    Science.gov (United States)

    Ikem, Innocent C; Ogunlusi, Johnson D; Ine, Henry R

    2007-08-01

    Interlocking nails are commonly performed using an image intensifier. These are expensive and are not readily available in most resource-poor countries of the world. The aim of this study was to achieve interlocking nailing without the use of an image intensifier. This is a prospective descriptive analysis of 40 consecutive cases seen with shaft fractures of the humerus, femur, and tibia. Fracture fixation was done using Surgical Implant Generation Network (SIGN) nails. Forty limbs in 34 patients were studied. There were 12 females and 22 males, giving a ratio of 1:2. The mean age (years) was 35.75+/-13.16 and the range was 17-70 years. The studied bones were: humerus 10%, femur 65%, and tibia 25%. The fracture lines were: transverse 40%, oblique 15%, and communited 45%. Fracture grades were: closed 90%, grade I, 5%, grade II, 2.5%, and grade IIIA, 2.5%. Surgical approaches were: antegrade 62.5% and retrograde 37.5%. Indications for fixation were: recent fracture 92.5%, non-union 5%, and malunion 3%. Methods of reductions were: open 85% and closed 15%. The mean follow-up period (years) was 1.50+/-0.78. The union time averaged 3 months. Complication was mainly screw loosening due to severe osteoporoses in one case. It is, therefore, concluded that, with the aid of external jigs and slot finders, interlocking can be achieved without an image intensifier.

  5. Improved fluorescent X-ray image intensifying screen

    International Nuclear Information System (INIS)

    Landeghem, W.K. van; Suys, A.R.

    1981-01-01

    An X-ray image intensifying screen is described, which includes at least one fluorescent layer comprising phosphor particles dispersed in a binder and on top of such layer a protective layer containing a crosslinked polymer mass obtained by an acid-catalyzed reaction of a polymer or mixture of polymers containing reactive hydrogen atoms and a cross-linking agent, the cross-linking agent being an organic compound containing a plurality of etherified N-methylol groups. Examples are given of appropriate polymers and cross-linking agents. (author)

  6. Integrated Process Design, Control and Analysis of Intensified Chemical Processes

    DEFF Research Database (Denmark)

    Mansouri, Seyed Soheil

    chemical processes; for example, intensified processes such as reactive distillation. Most importantly, it identifies and eliminates potentially promising design alternatives that may have controllability problems later. To date, a number of methodologies have been proposed and applied on various problems......, that the same principles that apply to a binary non-reactive compound system are valid also for a binary-element or a multi-element system. Therefore, it is advantageous to employ the element based method for multicomponent reaction-separation systems. It is shown that the same design-control principles...

  7. Study of secondary X-rays from radiographic intensifying screens

    International Nuclear Information System (INIS)

    Barroso, R.C.; Eichler, J.; Lopes, R.T.; Cardoso, S.C.

    1998-01-01

    To reduce the radiation dose in radiology, fluorescent intensifying screens for X-ray films are used. They produce visible light which increases the efficiency of the film. In addition, there are two other effects that will degrade the image resolution. First, the gadolinium present in the screens produces X-rays isotropically. Second, the primary radiation can be scattered elastically (Rayleigh scattering) and inelastically (Compton scattering). The intensity and angular distribution of these secondary radiation were measured, showing that the ratio of secondary-to-primary radiation incident on the X-ray film is about 16%. (orig.)

  8. Selection of Rational Heat Transfer Intensifiers in the Heat Exchanger

    Directory of Open Access Journals (Sweden)

    S. A. Burtsev

    2016-01-01

    Full Text Available The paper considers the applicability of different types of heat transfer intensifiers in the heat exchange equipment. A review of the experimental and numerical works devoted to the intensification of the dimpled surface, surfaces with pins and internally ribbed surface were presented and data on the thermal-hydraulic characteristics of these surfaces were given. We obtained variation of thermal-hydraulic efficiency criteria for 4 different objective functions and 15 options for the intensification of heat transfer. This makes it possible to evaluate the advantages of the various heat transfer intensifiers. These equations show influence of thermal and hydraulic characteristics of the heat transfer intensifiers (the values of the relative heat transfer and drag coefficients on the basic parameters of the shell-and-tube heat exchanger: the number and length of the tubes, the volume of the heat exchanger matrix, the coolant velocity in the heat exchanger matrix, coolant flow rate, power to pump coolant (or pressure drop, the amount of heat transferred, as well as the average logarithmic temperature difference. The paper gives an example to compare two promising heat transfer intensifiers in the tubes and shows that choosing the required efficiency criterion to search for optimal heat exchanger geometry is of importance. Analysis is performed to show that a dimpled surface will improve the effectiveness of the heat exchanger despite the relatively small value of the heat transfer intensification, while a significant increase in drag of other heat transfer enhancers negatively affects their thermalhydraulic efficiency. For example, when comparing the target functions of reducing the heat exchanger volume, the data suggest that application of dimpled surfaces in various fields of technology is possible. But there are also certain surfaces that can reduce the parameters of a heat exchanger. It is shown that further work development should be aimed at

  9. Development of a 3-dimensional CT using an image intensifier

    International Nuclear Information System (INIS)

    Toyofuku, Fukai

    1992-01-01

    A prototype of three-dimensional CT (Fluoroscopic CT) has been developed using an image intensifier as a two-dimensional X-ray detector. A patient on a rotating table is projected onto an image intensifier by a cone beam of X-ray from the X-ray tube. A total of 390 projection images covering 180 degrees are acquired in a single scan (13 sec) and stored on a digital frame recorder (512 x 256 x 8-bit x 480). The transverse axial images are reconstructed by using the usual CT reconstruction algorithm, while longitudinal section images such as sagittal, coronal, oblique, and panoramic images are obtained by directly back-projecting the filtered projection image onto the sections. The radiation exposure was measured with an ionization chamber, and the exposure of the present fluoroscopic CT is about 10 to 20 times less than that of conventional X-ray CT. A similar monochromatic X-ray CT system has also been developed using synchrotron radiation. Large area parallel X-rays are obtained from a wiggler beam using a silicon crystal with [311] asymmetric reflection. By taking two images above and below iodine K-absorption edge (33.17 keV), iodine image is obtained. (author)

  10. Characterization of a fiber-taper charge-coupled device system for plastic scintillation dosimetry and comparison with the traditional lens system

    International Nuclear Information System (INIS)

    Gagnon, Louis-Philippe; Beddar, Sam; Beaulieu, Luc

    2015-01-01

    Purpose: To compare the signal-to-noise ratio (SNR), dose sensitivity and stability, and reproducibility of a lens-less charge-coupled device (CCD) photon-counting system with those of a traditional CCD + lens photon-counting system for plastic scintillation detectors (PSDs). Methods: The PSD used in this study was made from a 1-mm diameter, 2-mm long BCF60 scintillating fiber (emission peak at 530 nm) coupled to a 2.6-m Eska GH-4001 clear plastic fiber. This PSD was coupled to either a fiber-taper-based photon-counting system (FTS) or a lens-based photon-counting system (LS). In the FTS, the fiber-taper was attached to a 2048 × 2048 pixel, uncooled Alta 4020 polychromatic CCD camera. The LS consisted of a 1600 × 1200 pixel Alta 2020 polychromatic CCD camera (cooled to −18 °C) with a 50-mm lens with f/# = 1. Dose measurements were made under the same conditions for each system (isocentric setup; depth of 1.5 cm in solid water using a 10 × 10 cm 2 field size and 6-MV photon beam). The performance of each system was determined and compared, using the chromatic Čerenkov removal method to account for the stem effects produced in the clear plastic fiber. Results: The FTS increased the light collected by a factor of 4 compared with the LS, for the same dose measurements. This gain was possible because the FTS was not limited by the optical aberration that comes with a lens system. Despite a 45 °C operating temperature difference between the systems, the SNR was 1.8–1.9 times higher in the FTS than in the LS, for blue and green channels respectively. Low-dose measurements of 1.0 and 0.5 cGy were obtained with an accuracy of 3.4% and 5.6%, respectively, in the FTS, compared with 5.8% and 15.9% in the LS. The FTS provided excellent dose measurement stability as a function of integration time, with at most a 1% difference at 5 cGy. Under the same conditions, the LS system produced a measurement difference between 2 and 3%. Conclusion: Our results showed that

  11. Quality control of image-intensifier television chains in Finland

    International Nuclear Information System (INIS)

    Pirinen, M.

    1989-01-01

    There are some 500 image-intensifier television (TV) chains connected to fluoroscopic units in Finland, most installed in the 1970s, although the oldest still in use date back to the late 1960s. To establish performance levels of the chains, 300 of them were assessed in 1982 by the Finnish Centre for Radiation and Nuclear Safety (STUK). Results showed great diversity in the condition of the chains. The main reason was lack of periodical quality assurance of the chains. Recommendations for limits were established from results of assessing three parameters describing the condition of the chains: spatial resolution, automatically controlled dose-rate and contrast sensitivity. Recommendations also advise hospitals on how to arrange alternative quality assurance measurements and observations, either by hospital's maintenance staff, the manufacturer, or the supervising authority (STUK). Results following adoption of the recommendations by hospitals are presented. (author)

  12. Marfan syndrome gene search intensifies following identification of basic defect

    Energy Technology Data Exchange (ETDEWEB)

    Randall, T.

    1990-10-03

    Somewhere, quite possible along chromosomes 8 and/or 15, the gene(s) for Marfan syndrome will be found. The search is intensifying following a report that faulty scaffolding in the body's connective tissue appears to be the long sought after defect behind the syndrome, and inherited disorder that has caused the premature death of young, healthy-looking individuals. Finding that something in the living masonry of the human body has proven to be a 30-year inquisition of nearly two dozen molecules that has engaged investigators worldwide. Historically, researchers have searched for a structural flaw in one of the collagen molecules to explain the cause of Marfan Syndrome. Using monoclonal antibodies, researchers have implicated microfibrils, the extracellular filaments that provide a matrix for the deposit of elastin during embryonic development.

  13. Sustainable and Intensified Design of a Biodiesel Production Process

    DEFF Research Database (Denmark)

    Mansouri, Seyed Soheil; Ismail, Muhammad I.; Babi, Deenesh Kavi

    impact and maximum profitability is needed. In this work a computer-aided framework for process synthesis and process intensification is applied for sustainable production of biodiesel from pure/waste palm oil as the feedstock. This approach examines several biodiesel processing routes that were...... collected through available data and current technologies reported in the literature. Using this information, a generic superstructure of processing routes was created that described a network of configurations representing multiple designs for the production of biodiesel. Therefore, based on the currently...... of economic and environmental sustainability was identified. For the case of biodiesel production, the intensified process alternative turned out to be the most economical and more sustainable than other alternatives. The computer-aided methods and tools used in this work are: SustainPro (method and tool...

  14. Dynamic behavior of the intensified alternative configurations for quaternary distillation

    DEFF Research Database (Denmark)

    Ramirez-Marquez, Cesar; Cabrera-Ruiz, Julián; Juan Gabriel Segovia-Hernandez, Juan Gabriel

    2016-01-01

    Process intensification emerges as an important tool in the synthesis of multicomponent distillation configurations aimed at the reduction of the energy use and capital costs. Operational and fixed costs savings coupled with simplicity and controllability design configurations appear as an essent......Process intensification emerges as an important tool in the synthesis of multicomponent distillation configurations aimed at the reduction of the energy use and capital costs. Operational and fixed costs savings coupled with simplicity and controllability design configurations appear...... value decomposition technique in all frequency domain. In order to complete the control study, the distillation schemes were subjected to closed-loop dynamic simulations. The results show that there are cases in which the intensified sequences do not only provide energy savings, but also may offer...

  15. System Design and Performance Test of Hydraulic Intensifier

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyoung Eui; Lee, Gi Chun [Korea Institute of Machinery and Materials, Daejeon (Korea, Republic of); Kim, Jae Hoon [Chungnam National University, Daejeon (Korea, Republic of)

    2010-07-15

    Components such as pressure vessel, hydraulic hose assembly, accumulator, hydraulic cylinder, hydraulic valve, pipe, etc., are tested under the impulse-pressure conditions prescribed in ISO and SAE standards. The impulse pressure test machine needs to have a high pressure, a precise control system and a long life. It should satisfy the requirements for fabrication of the impulse tester to generate ultra high pressure in the hydraulic system. In the impulse tester, a servo-valve control system is adopted; although the control application is convenient, it is expensive owing to the cost of developing the system. The type of the control system determines the pressure wave, which affects the components that are tested. In this study, the manufacturing process and the intensifier system design related to the flow, pressure, and the increasing rate of pressure are investigated. The results indicate the ultra high pressure waves in the system.

  16. New intensifying screens in clinical radiology. Pt. 2

    International Nuclear Information System (INIS)

    Freyschmidt, J.; Saure, D.; Hagemann, G.

    1976-01-01

    A clinically applicable procedure for testing new intensifying rare earth screens, as well as the special Siemens' screen is described. The results are related to universal screeens. The film-screen combination α 4XD (gadolinium oxysulphide with normal, green sensitive film) results in a reduction of radiation dose to half with detail comparable with universal screens. The Siemens' special screen has similar advantages. Screens with a higher intensification factor and reduction of the mAs to one sixth results in loss of detail. This does not necessarily reduce their clinical use if they are used for appropriate purposes. The results of this clinically orientated technique agreed well with physically objective methods using lead grids. The advantages of the new screens are discussed in terms of their practical application. (orig.) [de

  17. Impacts of Intensified Agriculture Developments on Marsh Wetlands

    Directory of Open Access Journals (Sweden)

    Zhaoqing Luan

    2013-01-01

    Full Text Available A spatiotemporal analysis on the changes in the marsh landscape in the Honghe National Nature Reserve, a Ramsar reserve, and the surrounding farms in the core area of the Sanjiang Plain during the past 30 years was conducted by integrating field survey work with remote sensing techniques. The results indicated that intensified agricultural development had transformed a unique natural marsh landscape into an agricultural landscape during the past 30 years. Ninety percent of the natural marsh wetlands have been lost, and the areas of the other natural landscapes have decreased very rapidly. Most dry farmland had been replaced by paddy fields during the progressive change of the natural landscape to a farm landscape. Attempts of current Chinese institutions in preserving natural wetlands have achieved limited success. Few marsh wetlands have remained healthy, even after the establishment of the nature reserve. Their ecological qualities have been declining in response to the increasing threats to the remaining wetland habitats. Irrigation projects play a key role in such threats. Therefore, the sustainability of the natural wetland ecosystems is being threatened by increased regional agricultural development which reduced the number of wetland ecotypes and damaged the ecological quality.

  18. Direct view panel type X-ray image intensifier tube

    International Nuclear Information System (INIS)

    Yang, S.-P.; Robbins, C.D.; Merrit, E.

    1977-01-01

    A panel shaped, proximity type, X-ray image intensifier tube for medical X-ray fluoroscopy use is described. It has all linear components and yet a high brightness gain, in excess of 4,000 cd-sec/m 2 -R, the tube being comprised of a rugged metallic tube envelope, an inwardly concave metallic input window, a directly viewable full size output display screen, and a scintillator-photocathode screen having a thickness of at least 200 microns for a high X-ray photon utilization ability as well as X-ray stopping power, the scintillator-photocathode screen being suspended on insulators within the envelope and in between the input window and the output screen. The scintillator-photocathode screen is spaced from the output screen by at least 8mm to allow the application of a high negative potential at the scintillator-photocathode screen with respect to the output screen for high gain with low field emission, since all of the remaining components within the tube envelope are at neutral potential with respect to the output display screen. (Auth.)

  19. Social exclusion intensifies anxiety-like behavior in adolescent rats.

    Science.gov (United States)

    Lee, Hyunchan; Noh, Jihyun

    2015-05-01

    Social connection reduces the physiological reactivity to stressors, while social exclusion causes emotional distress. Stressful experiences in rats result in the facilitation of aversive memory and induction of anxiety. To determine the effect of social interaction, such as social connection, social exclusion and equality or inequality, on emotional change in adolescent distressed rats, the emotional alteration induced by restraint stress in individual rats following exposure to various social interaction circumstances was examined. Rats were assigned to one of the following groups: all freely moving rats, all rats restrained, rats restrained in the presence of freely moving rats and freely moving rats with a restrained rat. No significant difference in fear-memory and sucrose consumption between all groups was found. Change in body weight significantly increased in freely moving rats with a restrained rat, suggesting that those rats seems to share the stressful experience of the restrained rat. Interestingly, examination of the anxiety-like behavior revealed only rats restrained in the presence of freely moving rats to have a significant increase, suggesting that emotional distress intensifies in positions of social exclusion. These results demonstrate that unequally excluded social interaction circumstances could cause the amplification of distressed status and anxiety-related emotional alteration. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Elite synchronized swimmers display decreased energy availability during intensified training.

    Science.gov (United States)

    Schaal, K; Tiollier, E; Le Meur, Y; Casazza, G; Hausswirth, C

    2017-09-01

    Elite synchronized swimmers follow high-volume training regimen that result in elevated rates of exercise energy expenditure (ExEE). While adequate energy intake (EI) is important to optimize recovery, a number of sport-specific constraints may lead to chronically low energy availability (EA = EI-ExEE). This study aimed to quantify changes in EA, endocrine markers of energy conservation, and perceived fatigue in synchronized swimmers, during a week of baseline training followed by 4 weeks of intensified training (IT). EI, ExEE, and body composition were measured in nine swimmers at Baseline, midpoint (IT WK 2 ), and end of IT (IT WK 4 ). Waking saliva samples were obtained to measure [leptin] s , [ghrelin] s , and [cortisol] s . Fatigue ratings were provided daily. ExEE increased by 27% during IT. Swimmers increased EI from Baseline to IT WK 2 , but decreased it significantly from IT WK 2 to IT WK 4 . EA, fat mass, and [leptin] s decreased from Baseline to IT WK 4 , while [ghrelin] s increased significantly. Fatigue at IT WK 4 was inversely correlated with Baseline EI and EA. The significant decrease in EA was accompanied by endocrine signs of energy conservation in elite swimmers. As perceived fatigue was associated with low EA, particular attention should be paid to these athletes' energy intake during phases of heavy training. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  1. Tide-surge Interaction Intensified by the Taiwan Strait

    Science.gov (United States)

    Zhang, Wen-Zhou; Shi, Fengyan; Hong, Hua-Sheng; Shang, Shao-Ping; Kirby, James T.

    2010-06-01

    The Taiwan Strait is a long and wide shelf-channel where the hydrodynamics is extremely complex, being characterized by strong tides, and where storm surges frequently occur during the typhoon season. Obvious oscillations due to tide-surge interaction were observed by tide gauges along the northern Fujian coast, the west bank of the Taiwan Strait, during Typhoon Dan (1999). Numerical experiments indicate that nonlinear bottom friction (described by the quadratic formula) is a major factor to predict these oscillations while the nonlinear advective terms and the shallow water effect have little contribution. It is found that the tide-surge interaction in the northern portion of the Taiwan Strait is intensified by the strait. Simulations based on simplified topographies with and without the island of Taiwan show that, in the presence of the island, the channel effect strengthens tidal currents and tends to align the major axes of tidal ellipses along the channel direction. Storm-induced currents are also strengthened by the channel. The pattern of strong tidal currents and storm-induced currents along the channel direction enhances tide-surge interaction via the nonlinear bottom friction, resulting in the obvious oscillations along the northern Fujian coast.

  2. 40° image intensifier tubes in an integrated helmet system

    Science.gov (United States)

    Schreyer, Herbert; Boehm, Hans-Dieter V.; Svedevall, B.

    1993-12-01

    EUROCOPTER has been under contract to the French and German ministries of defence for five years to develop the TIGER, a second generation anti-tank helicopter. A piloting thermal imager has been installed on a steerable platform in the helicopter nose in order to achieve the possibility of flying round the clock. In addition to this sensor, which is sensitive at a wavelength of 10 micrometers , the German side has proposed using an Integrated Helmet System in the PAH 2. This helmet, manufactured by GEC-Marconi Avionics, incorporates two cathode ray tubes (CRT) and two image intensifier tubes which allow the pilot to use an additional sensor in the visible and near infrared spectrum. The electronic part will be built by Teldix. EUROCOPTER DEUTSCHLAND has received the first demonstrator of this helmet for testing in the EUROCOPTER Visionics Laboratory. Later, the C-prototype will be integrated into a BK 117 helicopter (AVT Avionik Versuchstrager). This new helmet has a field of view of 40 degree(s), and exit pupil of 15 mm and improved possibilities of adjusting the optical part. Laboratory tests have been carried out to test important parameters like optical resolution under low light level conditions, field of view, eye relief or exit pupil. The CRT channels have been tested for resolution, distortion, vignetting and homogeneity. The requirements and the properties of the helmet, test procedures and the results of these tests are presented in the paper.

  3. X-ray image intensifier camera tubes and semiconductor targets

    International Nuclear Information System (INIS)

    1979-01-01

    A semiconductor target for use in an image intensifier camera tube and a camera using the target are described. The semiconductor wafer for converting an electron image onto electrical signal consists mainly of a collector region, preferably n-type silicon. It has one side for receiving the electron image and an opposite side for storing charge carriers generated in the collector region by high energy electrons forming a charge image. The first side comprises a highly doped surface layer covered with a metal buffer layer permeable to the incident electrons and thick enough to dissipate some of the incident electron energy thereby improving the signal-to-noise ratio. This layer comprises beryllium on niobium on the highly doped silicon surface zone. Low energy Kα X-ray radiation is generated in the first layer, the radiation generated in the second layer (mainly Lα radiation) is strongly absorbed in the silicon layer. A camera tube using such a target with a photocathode for converting an X-ray image into an electron image, means to project this image onto the first side of the semiconductor wafer and means to read out the charge pattern on the second side are also described. (U.K.)

  4. 21 CFR 892.1650 - Image-intensified fluoroscopic x-ray system.

    Science.gov (United States)

    2010-04-01

    ... fluoroscopic x-ray system. (a) Identification. An image-intensified fluoroscopic x-ray system is a device... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Image-intensified fluoroscopic x-ray system. 892... equipment, patient and equipment supports, component parts, and accessories. (b) Classification. Class II...

  5. 21 CFR 892.1660 - Non-image-intensified fluoroscopic x-ray system.

    Science.gov (United States)

    2010-04-01

    ... fluoroscopic x-ray system. (a) Identification. A non-image-intensified fluoroscopic x-ray system is a device... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Non-image-intensified fluoroscopic x-ray system... display equipment, patient and equipment supports, component parts, and accessories. (b) Classification...

  6. Two micron pore size MCP-based image intensifiers

    Science.gov (United States)

    Glesener, John; Estrera, Joseph

    2010-02-01

    Image intensifiers (I2) have many advantages as detectors. They offer single photon sensitivity in an imaging format, they're light in weight and analog I2 systems can operate for hours on a single AA battery. Their light output is such as to exploit the peak in color sensitivity of the human eye. Until recent developments in CMOS sensors, they also were one of the highest resolution sensors available. The closest all solid state solution, the Texas Instruments Impactron chip, comes in a 1 megapixel format. Depending on the level of integration, an Impactron based system can consume 20 to 40 watts in a system configuration. In further investing in I2 technology, L-3 EOS determined that increasing I2 resolution merited a high priority. Increased I2 resolution offers the system user two desirable options: 1) increased detection and identification ranges while maintaining field-of-view (FOV) or 2) increasing FOV while maintaining the original system resolution. One of the areas where an investment in resolution is being made is in the microchannel plate (MCP). Incorporation of a 2 micron MCP into an image tube has the potential of increasing the system resolution of currently fielded systems. Both inverting and non-inverting configurations are being evaluated. Inverting tubes are being characterized in night vision goggle (NVG) and sights. The non-inverting 2 micron tube is being characterized for high resolution I2CMOS camera applications. Preliminary measurements show an increase in the MTF over a standard 5 micron pore size, 6 micron pitch plate. Current results will be presented.

  7. Restraint stress intensifies interstitial K+ accumulation during severe hypoxia

    Directory of Open Access Journals (Sweden)

    Christian eSchnell

    2012-03-01

    Full Text Available Chronic stress affects neuronal networks by inducing dendritic retraction, modifying neuronal excitability and plasticity, and modulating glial cells. To elucidate the functional consequences of chronic stress for the hippocampal network, we submitted adult rats to daily restraint stress for three weeks (6 h/day. In acute hippocampal tissue slices of stressed rats, basal synaptic function and short-term plasticity at Schaffer collateral/CA1 neuron synapses were unchanged while long-term potentiation was markedly impaired. The spatiotemporal propagation pattern of hypoxia-induced spreading depression episodes was indistinguishable among control and stress slices. However, the duration of the extracellular direct current (DC potential shift was shortened after stress. Moreover, K+ fluxes early during hypoxia were more intense, and the postsynaptic recoveries of interstitial K+ levels and synaptic function were slower. Morphometric analysis of immunohistochemically stained sections suggested hippocampal shrinkage in stressed rats, and the number of cells that are immunoreactive for GFAP (glial fibrillary acidic protein was increased in the CA1 subfield indicating activation of astrocytes. Western blots showed a marked downregulation of the inwardly rectifying K+ channel Kir4.1 in stressed rats. Yet, resting membrane potentials, input resistance and K+-induced inward currents in CA1 astrocytes were indistinguishable from controls. These data indicate an intensified interstitial K+ accumulation during hypoxia in the hippocampus of chronically stressed rats which seems to arise from a reduced interstitial volume fraction rather than impaired glial K+ buffering. One may speculate that chronic stress aggravates hypoxia-induced pathophysiological processes in the hippocampal network and that this has implications for the ischemic brain.

  8. Predator cannibalism can intensify negative impacts on heterospecific prey.

    Science.gov (United States)

    Takatsu, Kunio; Kishida, Osamu

    2015-07-01

    Although natural populations consist of individuals with different traits, and the degree of phenotypic variation varies among populations, the impact of phenotypic variation on ecological interactions has received little attention, because traditional approaches to community ecology assume homogeneity of individuals within a population. Stage structure, which is a common way of generating size and developmental variation within predator populations, can drive cannibalistic interactions, which can affect the strength of predatory effects on the predator's heterospecific prey. Studies have shown that predator cannibalism weakens predatory effects on heterospecific prey by reducing the size of the predator population and by inducing less feeding activity of noncannibal predators. We predict, however, that predator cannibalism, by promoting rapid growth of the cannibals, can also intensify predation pressure on heterospecific prey, because large predators have large resource requirements and may utilize a wider variety of prey species. To test this hypothesis, we conducted an experiment in which we created carnivorous salamander (Hynobius retardatus) populations with different stage structures by manipulating the salamander's hatch timing (i.e., populations with large or small variation in the timing of hatching), and explored the resultant impacts on the abundance, behavior, morphology, and life history of the salamander's large heterospecific prey, Rana pirica frog tadpoles. Cannibalism was rare in salamander populations having small hatch-timing variation, but was frequent in those having large hatch-timing variation. Thus, giant salamander cannibals occurred only in the latter. We clearly showed that salamander giants exerted strong predation pressure on frog tadpoles, which induced large behavioral and morphological defenses in the tadpoles and caused them to metamorphose late at large size. Hence, predator cannibalism arising from large variation in the timing

  9. [Influence of human body target's spectral characteristics on visual range of low light level image intensifiers].

    Science.gov (United States)

    Zhang, Jun-Ju; Yang, Wen-Bin; Xu, Hui; Liu, Lei; Tao, Yuan-Yaun

    2013-11-01

    To study the effect of different human target's spectral reflective characteristic on low light level (LLL) image intensifier's distance, based on the spectral characteristics of the night-sky radiation and the spectral reflective coefficients of common clothes, we established a equation of human body target's spectral reflective distribution, and analyzed the spectral reflective characteristics of different human targets wearing the clothes of different color and different material, and from the actual detection equation of LLL image intensifier distance, discussed the detection capability of LLL image intensifier for different human target. The study shows that the effect of different human target's spectral reflective characteristic on LLL image intensifier distance is mainly reflected in the average reflectivity rho(-) and the initial contrast of the target and the background C0. Reflective coefficient and spectral reflection intensity of cotton clothes are higher than polyester clothes, and detection capability of LLL image intensifier is stronger for the human target wearing cotton clothes. Experimental results show that the LLL image intensifiers have longer visual ranges for targets who wear cotton clothes than targets who wear same color but polyester clothes, and have longer visual ranges for targets who wear light-colored clothes than targets who wear dark-colored clothes. And in the full moon illumination conditions, LLL image intensifiers are more sensitive to the clothes' material.

  10. Development of multi-color scintillator based X-ray image intensifier

    International Nuclear Information System (INIS)

    Nittoh, Koichi; Konagai, Chikara; Noji, Takashi

    2004-01-01

    A multi-color scintillator based high-sensitive, wide dynamic range and long-life X-ray image intensifier has been developed. An europium activated Y 2 O 2 S scintillator, emitting red, green and blue photons of different intensities, is utilized as the output fluorescent screen of the intensifier. By combining this image intensifier with a suitably tuned high sensitive color CCD camera, it is possible for a sensitivity of the red color component to become six times higher than that of the conventional image intensifier. Simultaneous emission of a moderate green color and a weak blue color covers different sensitivity regions. This widens the dynamic range, by nearly two orders of ten. With this image intensifier, it is possible to image simultaneously complex objects containing various different X-ray transmission from paper, water or plastic to heavy metals. This high sensitivity intensifier, operated at lower X-ray exposure, causes less degradation of scintillator materials and less colorization of output screen glass, and thus helps achieve a longer lifetime. This color scintillator based image intensifier is being introduced for X-ray inspection in various fields

  11. Characterization study of an intensified complementary metal-oxide-semiconductor active pixel sensor

    Science.gov (United States)

    Griffiths, J. A.; Chen, D.; Turchetta, R.; Royle, G. J.

    2011-03-01

    An intensified CMOS active pixel sensor (APS) has been constructed for operation in low-light-level applications: a high-gain, fast-light decay image intensifier has been coupled via a fiber optic stud to a prototype "VANILLA" APS, developed by the UK based MI3 consortium. The sensor is capable of high frame rates and sparse readout. This paper presents a study of the performance parameters of the intensified VANILLA APS system over a range of image intensifier gain levels when uniformly illuminated with 520 nm green light. Mean-variance analysis shows the APS saturating around 3050 Digital Units (DU), with the maximum variance increasing with increasing image intensifier gain. The system's quantum efficiency varies in an exponential manner from 260 at an intensifier gain of 7.45 × 103 to 1.6 at a gain of 3.93 × 101. The usable dynamic range of the system is 60 dB for intensifier gains below 1.8 × 103, dropping to around 40 dB at high gains. The conclusion is that the system shows suitability for the desired application.

  12. Examination of the lumbar vertebral column using large-screen image intensifier photofluorography

    International Nuclear Information System (INIS)

    Soimakallio, S.; Manninen, H.; Mahlamaeki, S.; Kuopio Central Hospital

    1985-01-01

    The OPTILUX 57 device with its large image intensifying screen is very efficient in visualizing the lumbar vertebrae. The article explains the techniques and summarizes results obtained in the examination of young sportsmen. (orig.) [de

  13. An alternative approach to contrast-detail testing of X-ray image intensifier systems

    International Nuclear Information System (INIS)

    Kotre, C.J.; Marshall, N.W.; Faulkner, K.

    1992-01-01

    The difficulties of making the results of threshold contrast-detail diameter tests on X-ray image intensifier systems consistent with published performance standards are discussed. The current approach to contrast-detail testing is described and an alternative method intended to give greater consistency for all image intensifier input field diameters proposed. The current and alternative test conditions are compared on two image intensifier systems. The results obtained show that the contrast-detail curves for image intensifier systems with a wide range of input field diameters can be effectively normalized to be directly comparable to a common reference standard by applying the proposed alternative test conditions. The implications of this result on the interpretation of the contrast-detail test are discussed. (author)

  14. Digital image intensifier radiography. One year's experience with a Polytron system

    International Nuclear Information System (INIS)

    Busch, H.P.; Lehmann, K.J.; Georgi, M.

    1989-01-01

    Since January 1988, digital image intensifier radiography has been used in the Clinic in Mannheim for DSA examinations and also in place of conventional screen/film examinations. Measurements have shown that compared with 100 mm and film/screen formats, digital radiography has poorer spatial resolution, but improved contrast resolution. The most common use of digital radiography was for examinations of the gastrointestinal tract. Using the demonstration of the mucosal fine relief pattern as a criterion of image quality, digital image intensifier radiography was able to achieve this satisfactorily. Comparison with film/screen examinations showed no loss of diagnostic information. Advantages of image intensifier radiography are reduced radiation dose, the possibility of postprocessing and economy. On the basis of 399 examinations, digital image intensifier radiography is now firmly established as part of the daily routine of the Mannheim Clinic. (orig.) [de

  15. A year's experience with a 57 cm image intensifier in a general X-ray room

    International Nuclear Information System (INIS)

    Georgi, M.; Prager, P.; Busch, H.P.; Strauss, L.; Wetzel, E.; Neumann, D.; Weiher, M.; Regenfuss, W.

    1985-01-01

    3342 patients were examined by means of a 57 cm image intensifier during one year. The installation permits examination with the patient standing or lying. The resolution was measured with a lead grid under conditions resembling actual practice and were found to be similar to those obtained with angiographic equipment. Using a medium format technique for examining the gut and vascular system resulted in radiographic quality which was not significantly different from the use of a large format technique. For examination of the skeleton, radiographic quality, using the intensifier, was markedly poorer than that resulting from Bucky examinations. There was no diagnostic difference when carrying out lymphograms. The large intensifier window of 53 cm was particularly advantageous for DSA of the pelvic and lower limb vessels when compared with smaller intensifiers. Possible savings of film and contrast medium costs are discussed. (orig.) [de

  16. Examination of the lumbar vertebral column using large-screen image intensifier photofluorography

    Energy Technology Data Exchange (ETDEWEB)

    Soimakallio, S.; Manninen, H.; Mahlamaeki, S.

    1985-01-01

    The OPTILUX 57 device with its large image intensifying screen is very efficient in visualizing the lumbar vertebrae. The article explains the techniques and summarizes results obtained in the examination of young sportsmen.

  17. Pick up screens for x-ray image intensifier tubes employing evaporated activated scintillator layer

    International Nuclear Information System (INIS)

    Spicer, W.E.

    1976-01-01

    The present invention relates in general to methods for making pick-up screens for x-ray image intensifier tubes and, more particularly, to an improved method wherein the x-ray fluorescent phosphor screen element is formed by evaporation of an alkali metal halide material in vacuum and condensing the evaporated material on an x-ray transparent portion of the x-ray intensifier tube, whereby a curved x-ray image pick-up screen is formed which has improved quantum efficiency and resolution. Such improved x-ray image intensifier tubes are especially useful for, but not limited in use to x-ray systems and for intensifying gamma ray images obtained in applications of nuclear medicine. 7 claims, 5 drawing figures

  18. Effects of intensified training and taper on immune function

    Directory of Open Access Journals (Sweden)

    Elena Papacosta

    2013-03-01

    Full Text Available Although resting immune function is not very different in athletes compared with non-athletes periods of intensified training (overreaching in already well trained athletes can result in a depression of immunity in the resting state. Illness-prone athletes appear to have an altered cytokine response to antigen stimulation and exercise. Having low levels of salivary IgA secretion also makes athletes more susceptible to upper respiratory tract infections. Overtraining is associated with recurrent infections and immunodepression is common, but immune functions do not seem to be reliable markers of impending overtraining. There are several possible causes of the diminution of immune function associated with periods of heavy training. One mechanism may simply be the cumulative effects of repeated bouts of intense exercise (with or without tissue damage with the consequent elevation of stress hormones, particularly glucocorticoids such as cortisol, causing temporary inhibition of TH-1 cytokines with a relative dampening of the cell-mediated response. When exercise is repeated frequently there may not be sufficient time for the immune system to recover fully. Tapering has been described as a gradual reduction in the training load which allows the recovery of physiological capacities that were impaired by previous intensive training and permits further training-induced adaptations to occur accompanied by competition performance enhancements. The majority of the studies that have examined the recovery of immunoendocrine responses during 1-3 week tapers in trained athletes have mainly reported enhanced performance, often accompanied by increased anabolic activity, reduced physiological stress and restoration of mucosal immunity and immune function.Quando se compara a função imune, em repouso, de atletas e não atletas, não se verificam grandes diferenças. Porém, períodos de treinamento intensificado ("overreaching" em atletas bem treinados podem

  19. Proton irradiation experiment for x-ray charge-coupled devices of the monitor of all-sky x-ray image mission onboard the international space station. 2. Degradation of dark current and identification of electron trap level

    CERN Document Server

    Miyata, E; Kamiyama, D

    2003-01-01

    We have investigated the radiation damage effects on a charge-coupled device (CCD) to be used for the Japanese X-ray mission, the monitor of all-sky X-ray image (MAXI), onboard the international space station (ISS). A temperature dependence of the dark current as a function of incremental dose is studied. We found that the protons having energy of >292 keV seriously increased the dark current of the devices. In order to improve the radiation tolerance of the devices, we have developed various device architectures to minimize the radiation damage in orbit. Among them, nitride oxide enables us to reduce the dark current significantly and therefore we adopted nitride oxide for the flight devices. We also compared the dark current of a device in operation and that out of operation during the proton irradiation. The dark current of the device in operation became twofold that out of operation, and we thus determined that devices would be turned off during the passage of the radiation belt. The temperature dependenc...

  20. Experimental and computational investigations of heat and mass transfer of intensifier grids

    International Nuclear Information System (INIS)

    Kobzar, Leonid; Oleksyuk, Dmitry; Semchenkov, Yuriy

    2015-01-01

    The paper discusses experimental and numerical investigations on intensification of thermal and mass exchange which were performed by National Research Centre ''Kurchatov Institute'' over the past years. Recently, many designs of heat mass transfer intensifier grids have been proposed. NRC ''Kurchatov Institute'' has accomplished a large scope of experimental investigations to study efficiency of intensifier grids of various types. The outcomes of experimental investigations can be used in verification of computational models and codes. On the basis of experimental data, we derived correlations to calculate coolant mixing and critical heat flux mixing in rod bundles equipped with intensifier grids. The acquired correlations were integrated in subchannel code SC-INT.

  1. Fabry-Perot interferometry using an image-intensified rotating-mirror streak camera

    International Nuclear Information System (INIS)

    Seitz, W.L.; Stacy, H.L.

    1983-01-01

    A Fabry-Perot velocity interferometer system is described that uses a modified rotating mirror streak camera to recrod the dynamic fringe positions. A Los Alamos Model 72B rotating-mirror streak camera, equipped with a beryllium mirror, was modified to include a high aperture (f/2.5) relay lens and a 40-mm image-intensifier tube such that the image normally formed at the film plane of the streak camera is projected onto the intensifier tube. Fringe records for thin (0.13 mm) flyers driven by a small bridgewire detonator obtained with a Model C1155-01 Hamamatsu and Model 790 Imacon electronic streak cameras are compared with those obtained with the image-intensified rotating-mirror streak camera (I 2 RMC). Resolution comparisons indicate that the I 2 RMC gives better time resolution than either the Hamamatsu or the Imacon for total writing times of a few microseconds or longer

  2. State of development and development trends of X-ray image intensifier television systems

    International Nuclear Information System (INIS)

    Pfeiler, M.; Haendle, J.

    1975-01-01

    Following a survey on the development of X-ray image intensifier television systems up to now, their further development is critically discussed with regard to the better image quality to be expected. The introduction of the high-resolving X-ray image intensifier already meant an improvement in image quality even though the television system remained the same. In the image intensifier television system, the distinguishability of small details suffers from noise effects. Therefore, a better image quality is especially advantageous in those ranges of application which allow a higher picture dose. 'Electronic' radiography, intermittent screening, co-storage of the spotfilm radiographs, videometry, video area kymography, and cardiac stroboscopy are examples some of which have already been tested in clinical practice. (orig./AK) [de

  3. Change of characteristic curves using light emission spectrum of the intensifying screens

    International Nuclear Information System (INIS)

    Yoon, Chul Ho; Kang, Hong Seok; Lee, In Ja; Huh, Joon

    1990-01-01

    This report is study about difference of H-D curve in regular film and ortho type film, and obtained results as follows: 1. In the blue-color emission intensifying screen, ortho type films and in the green-color emission intensifying screens, regular type are decreased in their gradient. 2. When joint use of regular type film and ortho type film, the gradient difference not seen in blue color screen. 3. The gradient difference seen clearly in G4, KM screens (green color emission intensifying). Especially, in part of high film density, the gradient difference are great. So we have to right use of screen and film because not matched used of there the sensitivity and gradient are decrease

  4. Fully Depleted Charge-Coupled Devices

    International Nuclear Information System (INIS)

    Holland, Stephen E.

    2006-01-01

    We have developed fully depleted, back-illuminated CCDs that build upon earlier research and development efforts directed towards technology development of silicon-strip detectors used in high-energy-physics experiments. The CCDs are fabricated on the same type of high-resistivity, float-zone-refined silicon that is used for strip detectors. The use of high-resistivity substrates allows for thick depletion regions, on the order of 200-300 um, with corresponding high detection efficiency for near-infrared and soft x-ray photons. We compare the fully depleted CCD to the p-i-n diode upon which it is based, and describe the use of fully depleted CCDs in astronomical and x-ray imaging applications

  5. High-speed videography combined with an x-ray image intensifier for dynamic radiography

    International Nuclear Information System (INIS)

    Bryant, L.E. Jr.

    1983-01-01

    The Spin Physics SP-2000 high-speed video system can be combined with an x-ray source, a dynamic event having internal (not directly visible) movement and an x-ray image intensifier to perform dynamic radiography. The cesium iodide input fluor and P-20 output fluor of the image intensifier have rapid decay to allow x-ray imaging up to 12,000 pictures per second. Applications of this technique include internal functioning of a compressor, turbulent-water action, and other mechanical actions

  6. Large-field image intensifiers versus conventional chest radiography: ROC study with simulated interstitial disease

    International Nuclear Information System (INIS)

    Winter, L.H.L.; Chakraborty, D.P.; Waes, P.F.G.M.

    1988-01-01

    Two image intensifier tubes have recently been introduced whose large imaging area makes them suitable for chest imaging (Phillips Pulmodiagnost TLX slit II and Siemens TX 57 large entrance field II). Both modalities present a 10 x 10-cm hard copy image to the radiologist. A receiver operating characteristic (ROC) curve study with simulated interstitial disease was performed to compare the image quality of these image intensifiers with conventional chest images. The relative ranking in terms of decreasing ROC areas was Siemens, conventional, and Philips. Compared with conventional imaging, none of the differences in ROC curve area were statistically significant at the 5% level

  7. An intensified esterification process of palm oil fatty acid distillate catalyzed by delipidated rice bran lipase.

    Science.gov (United States)

    Chong, Fui Chin; Tey, Beng Ti; Dom, Zanariah Mohd; Ibrahim, Nordin; Rahman, Russly Abd; Ling, Tau Chuan

    2006-09-07

    An intensified esterification process was operated by circulating 10 l of reaction mixtures, consisting of palm oil fatty acid distillate (PFAD) and glycerol in hexane, through a packed-bed reactor (PBR) filled with 10 kg of delipidated rice bran lipase (RBL). The influence of the process parameters, such as reaction temperature and type of water-removal agent, on the performance of this intensified esterification process were investigated. The highest degree of esterification (61%) was achieved at a reaction temperature of 65 masculineC, using silica gels as the water-removal agent. Thin-layer chromatography (TLC) analysis showed that the major composition of the esterified product was diacylglycerol.

  8. Pseudo real-time coded aperture imaging system with intensified vidicon cameras

    International Nuclear Information System (INIS)

    Han, K.S.; Berzins, G.J.

    1977-01-01

    A coded image displayed on a TV monitor was used to directly reconstruct a decoded image. Both the coded and the decoded images were viewed with intensified vidicon cameras. The coded aperture was a 15-element nonredundant pinhole array. The coding and decoding were accomplished simultaneously during the scanning of a single 16-msec TV frame

  9. Monte-Carlo simulation of spatial resolution of an image intensifier in a saturation mode

    Science.gov (United States)

    Xie, Yuntao; Wang, Xi; Zhang, Yujun; Sun, Xiaoquan

    2018-04-01

    In order to investigate the spatial resolution of an image intensifier which is irradiated by high-energy pulsed laser, a three-dimensional electron avalanche model was built and the cascade process of the electrons was numerically simulated. The influence of positive wall charges, due to the failure of replenishing charges extracted from the channel during the avalanche, was considered by calculating its static electric field through particle-in-cell (PIC) method. By tracing the trajectory of electrons throughout the image intensifier, the energy of the electrons at the output of the micro channel plate and the electron distribution at the phosphor screen are numerically calculated. The simulated energy distribution of output electrons are in good agreement with experimental data of previous studies. In addition, the FWHM extensions of the electron spot at phosphor screen as a function of the number of incident electrons are calculated. The results demonstrate that the spot size increases significantly with the increase in the number of incident electrons. Furthermore, we got the MTFs of the image intensifier by Fourier transform of a point spread function at phosphor screen. Comparison between the MTFs in our model and the MTFs by analytic method shows that spatial resolution of the image intensifier decreases significantly as the number of incident electrons increases, and it is particularly obvious when incident electron number greater than 100.

  10. Assessing impacts of intensified biomass production and biodiversity protection on ecosystem services provided by European forests

    NARCIS (Netherlands)

    Verkerk, P.J.; Mavsar, R.; Giergiczny, M.; Lindner, M.; Edwards, D.; Schelhaas, M.J.

    2014-01-01

    To develop viable strategies for intensifying the use of forest biomass and for increasing forest protection, impacts on ecosystem services need to be assessed. We investigated the biophysical and economic impacts of increased forest biomass production and biodiversity protection on forest ecosystem

  11. Assessment of uniformity and signal-to-noise ratio in radiological image intensifier TV systems

    International Nuclear Information System (INIS)

    Malone, J.F.; O'Connor, M.K.; Maher, K.P.

    1985-01-01

    A method of measuring the uniformity of radiological Image Intensifier-TV systems is described. Large non-uniformities were observed in the systems tested. A method of estimating the Signal-to-Noise Ratio in such systems is also presented and applied to characterise the effectiveness of the noise reduction techniques used in digital fluoroscopy. (author)

  12. Dust visualisation in TJ-II with intensified visible fast cameras

    International Nuclear Information System (INIS)

    Cal, E. de la; Pablos, J. L. de; Carralero, D.; Hidalgo, C.

    2010-01-01

    A visible fast camera equipped with an image Intensifier and atomic line filters is used in TJ-II for spectroscopic dust observation. First results show characteristic features depending on filter and clearly differing from those without the filters as is usually done in existing experiments. Preliminary discussions of the observed results are presented. (Author) 5 refs.

  13. Reemergence of Mycobacterium chimaera in Heater–Cooler Units despite Intensified Cleaning and Disinfection Protocol

    Science.gov (United States)

    Schreiber, Peter W.; Kuster, Stefan P.; Hasse, Barbara; Bayard, Cornelia; Rüegg, Christian; Kohler, Philipp; Keller, Peter M.; Bloemberg, Guido V.; Maisano, Francesco; Bettex, Dominique; Halbe, Maximilian; Sommerstein, Rami

    2016-01-01

    Invasive Mycobacterium chimaera infections after open-heart surgery have been reported internationally. These devastating infections result from aerosols generated by contaminated heater–cooler units used with extracorporeal circulation during surgery. Despite intensified cleaning and disinfection, surveillance samples from factory-new units acquired during 2014 grew nontuberculous mycobacteria after a median of 174 days. PMID:27649345

  14. Control of a Biological Nitrogen Removal Process in an Intensified Single Reactor Configuration

    DEFF Research Database (Denmark)

    Vangsgaard, Anna Katrine; Mauricio Iglesias, Miguel; Gernaey, Krist

    2013-01-01

    The nitrogen removing granular sludge process is a novel and intensified process. However, its stable operation and control remains a challenging problem. In this contribution, a new process oriented approach is used to develop, evaluate and benchmark control strategies to ensure stable operation...

  15. Intensified Voice Therapy: A New Model for the Rehabilitation of Patients Suffering from Functional Dysphonias

    Science.gov (United States)

    Fischer, Michael J.; Gutenbrunner, Christoph; Ptok, Martin

    2009-01-01

    The objective of this study was to evaluate a new intervention for chronic dysphonias, consisting of a 2-week outpatient treatment period using intensified voice therapy combined with elements of physical medicine, including physiotherapy (orthotherapy, detonisation and training of the trunk muscles, respiratory therapy and others), manual therapy…

  16. Dust visualisation in TJ-II with intensified visible Fast Cameras

    Energy Technology Data Exchange (ETDEWEB)

    Cal, E. de la; Pablos, J. L. de; Carralero, D.; Hidalgo, C.

    2010-10-21

    A visible fast camera equipped with an image Intensifier and atomic line filters is used in TJ-II for spectroscopic dust observation. First results show characteristic features depending on filter and clearly differing from those without the filters as is usually done in existing experiments. Preliminary discussions of the observed results are presented. (Author) 5 refs.

  17. Investigating the Effectiveness of Audio Input Enhancement on EFL Learners' Retention of Intensifiers

    Science.gov (United States)

    Negari, Giti Mousapour; Azizi, Aliye; Arani, Davood Khedmatkar

    2018-01-01

    The present study attempted to investigate the effects of audio input enhancement on EFL learners' retention of intensifiers. To this end, two research questions were formulated. In order to address these research questions, this study attempted to reject two null hypotheses. Pretest-posttest control group quasi-experimental design was employed to…

  18. Public Narratives under Intensified Market Conditions: Chile as a Critical Case

    Science.gov (United States)

    Santori, Diego

    2018-01-01

    This paper aims to extend existing theorisations around the notion of public narratives by analysing their regulatory effects under intensified market conditions. My analysis suggests that public narratives constitute a liminal space, one that it is not exclusively real or imaginary, factual or normative, but that simultaneously affects and is…

  19. Simulation of dental intensifying screen for intraoral radiographic using MCNP5 code

    International Nuclear Information System (INIS)

    Ferreira, Vanessa M.; Oliveira, Renato C.M.; Barros, Graiciany P.; Oliveira, Arno H.; Veloso, M. Auxiliadora F.

    2011-01-01

    One of basic principles for radiological protection is the optimization of techniques for obtain radiographic images, in way that the dose in the patient is kept as low as reasonably achievable (ALARA). Intensifying screens are used in medical radiology, which reduce considerably the dose rates in the production of radiographic images, maintaining the quality of these, while in dental radiology, there is no a intensifying screen available for intraoral examinations. From this technological requirement, this paper evaluates a computational modeling of an intensifying screen for use in intraoral radiography. For this, it was used the Monte Carlo code MCNP5 that allows the radiography simulation through the transport of electrons and photons in the different materials present in this examination. The goal of an intensifying screen is the conversion of X-ray photons to photons in the visible spectrum, knowing that radiographic films are more sensitive to light photons than to X-ray photons. So the screen should be composed of an efficient material for converting x-rays photons in light photons, therefore was made simulations using different materials, thicknesses and positions possible for placing screen in radiographic film in order to find the way more technically feasible. (author)

  20. Colour-the-INSight : Combining a direct view rifle sight with fused intensified and thermal imagery

    NARCIS (Netherlands)

    Hogervorst, M.A.; Jansen, C.; Toet, A.; Bijl, P.; Bakker, P.J.; Hiddema, A.C.; Vliet, S.F. van

    2012-01-01

    We present the design and evaluation of a new demonstrator rifle sight viewing system containing direct view, red aim point and fusion of an (uncooled, LWIR) thermal sensor with a digital image intensifier. Our goal is to create a system that performs well under a wide variety of (weather)

  1. Reemergence of Mycobacterium chimaera in Heater-Cooler Units despite Intensified Cleaning and Disinfection Protocol.

    Science.gov (United States)

    Schreiber, Peter W; Kuster, Stefan P; Hasse, Barbara; Bayard, Cornelia; Rüegg, Christian; Kohler, Philipp; Keller, Peter M; Bloemberg, Guido V; Maisano, Francesco; Bettex, Dominique; Halbe, Maximilian; Sommerstein, Rami; Sax, Hugo

    2016-10-01

    Invasive Mycobacterium chimaera infections after open-heart surgery have been reported internationally. These devastating infections result from aerosols generated by contaminated heater-cooler units used with extracorporeal circulation during surgery. Despite intensified cleaning and disinfection, surveillance samples from factory-new units acquired during 2014 grew nontuberculous mycobacteria after a median of 174 days.

  2. Influence of range-gated intensifiers on underwater imaging system SNR

    Science.gov (United States)

    Wang, Xia; Hu, Ling; Zhi, Qiang; Chen, Zhen-yue; Jin, Wei-qi

    2013-08-01

    Range-gated technology has been a hot research field in recent years due to its high effective back scattering eliminating. As a result, it can enhance the contrast between a target and its background and extent the working distance of the imaging system. The underwater imaging system is required to have the ability to image in low light level conditions, as well as the ability to eliminate the back scattering effect, which means that the receiver has to be high-speed external trigger function, high resolution, high sensitivity, low noise, higher gain dynamic range. When it comes to an intensifier, the noise characteristics directly restrict the observation effect and range of the imaging system. The background noise may decrease the image contrast and sharpness, even covering the signal making it impossible to recognize the target. So it is quite important to investigate the noise characteristics of intensifiers. SNR is an important parameter reflecting the noise features of a system. Through the use of underwater laser range-gated imaging prediction model, and according to the linear SNR system theory, the gated imaging noise performance of the present market adopted super second generation and generation Ⅲ intensifiers were theoretically analyzed. Based on the active laser underwater range-gated imaging model, the effect to the system by gated intensifiers and the relationship between the system SNR and MTF were studied. Through theoretical and simulation analysis to the image intensifier background noise and SNR, the different influence on system SNR by super second generation and generation Ⅲ ICCD was obtained. Range-gated system SNR formula was put forward, and compared the different effect influence on the system by using two kind of ICCDs was compared. According to the matlab simulation, a detailed analysis was carried out theoretically. All the work in this paper lays a theoretical foundation to further eliminating back scattering effect, improving

  3. Improved pregnancy outcome in type 1 diabetic women with microalbuminuria or diabetic nephropathy: effect of intensified antihypertensive therapy?

    DEFF Research Database (Denmark)

    Nielsen, Lene Ringholm; Damm, Peter; Mathiesen, Elisabeth R

    2009-01-01

    To describe pregnancy outcome in type 1 diabetic women with normoalbuminuria, microalbuminuria, or diabetic nephropathy after implementation of an intensified antihypertensive therapeutic strategy.......To describe pregnancy outcome in type 1 diabetic women with normoalbuminuria, microalbuminuria, or diabetic nephropathy after implementation of an intensified antihypertensive therapeutic strategy....

  4. Application of ultra-fast high-resolution gated-image intensifiers to laser fusion studies

    International Nuclear Information System (INIS)

    Lieber, A.J.; Benjamin, R.F.; Sutphin, H.D.; McCall, G.H.

    1975-01-01

    Gated-image intensifiers for fast framing have found high utility in laser-target interaction studies. X-ray pinhole camera photographs which can record asymmetries of laser-target interactions have been instrumental in further system design. High-resolution high-speed x-ray images of laser irradiated targets are formed using pinhole optics and electronically amplified by proximity focused channelplate intensifiers before being recorded on film. Spectral resolution is obtained by filtering. In these applications shutter duration is determined by source duration. Electronic gating serves to reduce background thereby enhancing signal-to-noise ratio. Cameras are used to view the self light of the interaction but may also be used for shadowgraphs. Sources for shadowgraphs may be sequenced to obtain a series of pictures with effective rates of 10 10 frame/s. Multiple aperatures have been used to obtain stereo x-ray views, yielding three dimensional information about the interactions. (author)

  5. 12-inch x-ray image intensifier with thin metal input window

    Energy Technology Data Exchange (ETDEWEB)

    Obata, Yoshiharu; Anno, Hidero; Harao, Norio [Toshiba Corp., Kawasaki, Kanagawa (Japan)

    1982-08-01

    Borosilicate glass has been used for X-ray input window of image intensifiers (I.I.) up to now. Now two new types of 12-inch metal I.I., RT12301C and RT12302C, have been developed. They use convex 1-mm aluminum (instead of 5-mm borosilicate glass) for the input window. Adopting a high-performance penta-electronic lens and a new type of light guide CsI film, these intensifiers have greatly improved contrast, quantum detection efficiency (QDE) and resolution capability. In spite of low dosage, image quality equivalent to that in the conventional direct radiograph is obtained through combined use of the new-type 12-inch metal I.I. with 0.3-mm small-focal-spot X-ray tube. Great contribution to digital radiography is expected of this I.I.

  6. Avalanche transistor pulser for fast-gated operation of micro-channel plate image-intensifiers

    International Nuclear Information System (INIS)

    Lundy, A.; Parker, J.R.; Lunsford, J.S.; Martin, A.D.

    1977-01-01

    Transistors operated in the avalanche mode are employed to generate a 1000 volt 10 to 30 nsec wide pulse with less than 4 nsec rise and fall times. This pulse is resistively attenuated to approximately equal to 270 volts and drives the image intensifier tube which is a load of approximately equal to 200 pf. To reduce stray inductance and capacitance, transistor chips were assembled on a thick-film hybrid substrate. Circuit parameters, operating conditions, and coupling to the microchannel plate image-intensifier (MCPI 2 ) tube are described. To provide dc operating voltages and control of transient voltages on the MCPI 2 tube a resistance-capacitance network has been developed which (a) places the MCPI 2 output phosphor at ground, (b) provides programmable gains in ''f-stop'' steps, and (c) minimizes voltage transients on the MCPI 2 tube

  7. Weakened cyclones, intensified anticyclones and recent extreme cold winter weather events in Eurasia

    International Nuclear Information System (INIS)

    Zhang Xiangdong; Lu Chuhan; Guan Zhaoyong

    2012-01-01

    Extreme cold winter weather events over Eurasia have occurred more frequently in recent years in spite of a warming global climate. To gain further insight into this regional mismatch with the global mean warming trend, we analyzed winter cyclone and anticyclone activities, and their interplay with the regional atmospheric circulation pattern characterized by the semi-permanent Siberian high. We found a persistent weakening of both cyclones and anticyclones between the 1990s and early 2000s, and a pronounced intensification of anticyclone activity afterwards. It is suggested that this intensified anticyclone activity drives the substantially strengthening and northwestward shifting/expanding Siberian high, and explains the decreased midlatitude Eurasian surface air temperature and the increased frequency of cold weather events. The weakened tropospheric midlatitude westerlies in the context of the intensified anticyclones would reduce the eastward propagation speed of Rossby waves, favoring persistence and further intensification of surface anticyclone systems. (letter)

  8. An Intensified Esterification Process of Palm Oil Fatty Acid Distillate Catalyzed by Delipidated Rice Bran Lipase

    Directory of Open Access Journals (Sweden)

    Fui Chin Chong

    2006-01-01

    Full Text Available An intensified esterification process was operated by circulating 10 l of reaction mixtures, consisting of palm oil fatty acid distillate (PFAD and glycerol in hexane, through a packed-bed reactor (PBR filled with 10 kg of delipidated rice bran lipase (RBL. The influence of the process parameters, such as reaction temperature and type of water-removal agent, on the performance of this intensified esterification process were investigated. The highest degree of esterification (61% was achieved at a reaction temperature of 65°C, using silica gels as the water-removal agent. Thin-layer chromatography (TLC analysis showed that the major composition of the esterified product was diacylglycerol.

  9. X-ray image intensifier/television systems for digital skeletal radiography

    International Nuclear Information System (INIS)

    Rowlands, J.A.; Hynes, D.M.; Edmonds, E.W.; Porter, A.J.; Toth, B.J.

    1987-01-01

    The imaging criteria for skeletal radiography (high resolution and low noise) relevant to the use of x-ray image intensifier/TV digital systems are discussed. It is shown from the modulation transfer function (MTF), noise, and phantom evaluations that conventional x-ray image intensifiers in conjunction with a 1,000-line Plumbicon or Saticon TV camera are in most respects suitable for skeletal radiography. The optimum focal spot size depends on a trade-off with motion blurring through the x-ray exposure time and so is a function of the clinical problem. Since the skeletal system is readily immobilized, a 0.3-mm focal spot size is nearly optimum

  10. Improving lactate metabolism in an intensified CHO culture process: productivity and product quality considerations.

    Science.gov (United States)

    Xu, Sen; Hoshan, Linda; Chen, Hao

    2016-11-01

    In this study, we discussed the development and optimization of an intensified CHO culture process, highlighting medium and control strategies to improve lactate metabolism. A few strategies, including supplementing glucose with other sugars (fructose, maltose, and galactose), controlling glucose level at Productivity and product quality attributes differences between batch, fed-batch, and concentrated fed-batch cultures were discussed. The importance of process and cell metabolism understanding when adapting the existing process to a new operational mode was demonstrated in the study.

  11. Quality control measurements of X-ray image-intensifier television chain systems

    International Nuclear Information System (INIS)

    Henshaw, E.T.

    1989-01-01

    The test methods and limiting values for the following basic parameters of an image intensifier TV system are presented in relation to (a) acceptance tests and (b) constancy tests: automatic gain and brightness control, video voltage output, monitor check (grey scale), geometric distortion, noise (low-contrast detectability), overall imaging ability, limiting resolution, uniformity of resolution, conversion factor, contrast ratio and measurement of field size. Several of these tests make use of the Leeds Test Objects. (author)

  12. Relationship between fatigue of generation II image intensifier and input illumination

    Science.gov (United States)

    Chen, Qingyou

    1995-09-01

    If there is fatigue for an image intesifier, then it has an effect on the imaging property of the night vision system. In this paper, using the principle of Joule Heat, we derive a mathematical formula for the generated heat of semiconductor photocathode. We describe the relationship among the various parameters in the formula. We also discuss reasons for the fatigue of Generation II image intensifier caused by bigger input illumination.

  13. A directional fast neutron detector using scintillating fibers and an intensified CCD camera system

    International Nuclear Information System (INIS)

    Holslin, Daniel; Armstrong, A.W.; Hagan, William; Shreve, David; Smith, Scott

    1994-01-01

    We have been developing and testing a scintillating fiber detector (SFD) for use as a fast neutron sensor which can discriminate against neutrons entering at angles non-parallel to the fiber axis (''directionality''). The detector/convertor component is a fiber bundle constructed of plastic scintillating fibers each measuring 10 cm long and either 0.3 mm or 0.5 mm in diameter. Extensive Monte Carlo simulations were made to optimize the bundle response to a range of fast neutron energies and to intense fluxes of high energy gamma-rays. The bundle is coupled to a set of gamma-ray insenitive electro-optic intensifiers whose output is viewed by a CCD camera directly coupled to the intensifiers. Two types of CCD cameras were utilized: 1) a standard, interline RS-170 camera with electronic shuttering and 2) a high-speed (up to 850 frame/s) field-transfer camera. Measurements of the neutron detection efficiency and directionality were made using 14 MeV neutrons, and the response to gamma-rays was performed using intense fluxes from radioisotopic sources (up to 20 R/h). Recently, the detector was constructed and tested using a large 10 cm by 10 cm square fiber bundle coupled to a 10 cm diameter GEN I intensifier tube. We present a description of the various detector systems and report the results of experimental tests. ((orig.))

  14. Signal-to-noise characterization of time-gated intensifiers used for wide-field time-domain FLIM

    Energy Technology Data Exchange (ETDEWEB)

    McGinty, J; Requejo-Isidro, J; Munro, I; Talbot, C B; Dunsby, C; Neil, M A A; French, P M W [Photonics Group, Blackett Laboratory, Imperial College London, Prince Consort Road, London, SW7 2BW (United Kingdom); Kellett, P A; Hares, J D, E-mail: james.mcginty@imperial.ac.u [Kentech Instruments Ltd, Isis Building, Howbery Park, Wallingford, OX10 8BA (United Kingdom)

    2009-07-07

    Time-gated imaging using gated optical intensifiers provides a means to realize high speed fluorescence lifetime imaging (FLIM) for the study of fast events and for high throughput imaging. We present a signal-to-noise characterization of CCD-coupled micro-channel plate gated intensifiers used with this technique and determine the optimal acquisition parameters (intensifier gain voltage, CCD integration time and frame averaging) for measuring mono-exponential fluorescence lifetimes in the shortest image acquisition time for a given signal flux. We explore the use of unequal CCD integration times for different gate delays and show that this can improve the lifetime accuracy for a given total acquisition time.

  15. Novel heat–integrated and intensified biorefinery process for cellulosic ethanol production from lignocellulosic biomass

    International Nuclear Information System (INIS)

    Nhien, Le Cao; Long, Nguyen Van Duc; Lee, Moonyong

    2017-01-01

    Highlights: • A compact biorefinery design was proposed for cellulosic ethanol purification. • Actual fermentation broth from lignocellulosic biomass was considered. • Process integration and intensification achieves competitive biorefinery context. • The response surface method optimizes the complex column structure effectively. • The proposed process could save up to 47.6% of total annual cost. - Abstract: Biofuels have the most potential as an alternative to fossil fuels and overcoming global warming, which has become one of the most serious environmental issues over the past few decades. As the world confronts food shortages due to an increase in world population, the development of biofuels from inedible lignocellulosic feedstock may be more sustainable in the long term. Inspired by the NREL conventional process, this paper proposes a novel heat–integrated and intensified biorefinery design for cellulosic ethanol production from lignocellulosic biomass. For the preconcentration section, heat pump assisted distillation and double–effect heat integration were evaluated, while a combination of heat–integrated technique and intensified technique, extractive dividing wall column (EDWC), was applied to enhance the process energy and cost efficiency for the purification section. A biosolvent, glycerol, which can be produced from biodiesel production, was used as the extracting solvent in an EDWC to obtain a high degree of integration in a biorefinery context. All configuration alternatives were simulated rigorously using Aspen Plus were based on the energy requirements, total annual costs (TAC), and total carbon dioxide emissions (TCE). In addition, the structure of the EDWC was optimized using the reliable response surface method, which was carried out using Minitab statistical software. The simulation results showed that the proposed heat–integrated and intensified process can save up to 47.6% and 56.9% of the TAC and TCE for the purification

  16. Dispersal limitation drives successional pathways in Central Siberian forests under current and intensified fire regimes.

    Science.gov (United States)

    Tautenhahn, Susanne; Lichstein, Jeremy W; Jung, Martin; Kattge, Jens; Bohlman, Stephanie A; Heilmeier, Hermann; Prokushkin, Anatoly; Kahl, Anja; Wirth, Christian

    2016-06-01

    Fire is a primary driver of boreal forest dynamics. Intensifying fire regimes due to climate change may cause a shift in boreal forest composition toward reduced dominance of conifers and greater abundance of deciduous hardwoods, with potential biogeochemical and biophysical feedbacks to regional and global climate. This shift has already been observed in some North American boreal forests and has been attributed to changes in site conditions. However, it is unknown if the mechanisms controlling fire-induced changes in deciduous hardwood cover are similar among different boreal forests, which differ in the ecological traits of the dominant tree species. To better understand the consequences of intensifying fire regimes in boreal forests, we studied postfire regeneration in five burns in the Central Siberian dark taiga, a vast but poorly studied boreal region. We combined field measurements, dendrochronological analysis, and seed-source maps derived from high-resolution satellite images to quantify the importance of site conditions (e.g., organic layer depth) vs. seed availability in shaping postfire regeneration. We show that dispersal limitation of evergreen conifers was the main factor determining postfire regeneration composition and density. Site conditions had significant but weaker effects. We used information on postfire regeneration to develop a classification scheme for successional pathways, representing the dominance of deciduous hardwoods vs. evergreen conifers at different successional stages. We estimated the spatial distribution of different successional pathways under alternative fire regime scenarios. Under intensified fire regimes, dispersal limitation of evergreen conifers is predicted to become more severe, primarily due to reduced abundance of surviving seed sources within burned areas. Increased dispersal limitation of evergreen conifers, in turn, is predicted to increase the prevalence of successional pathways dominated by deciduous hardwoods

  17. Intensified Multifactorial Intervention in Type 2 Diabetes and Microalbuminuria Reduces End Stage Renal Disease and Mortality

    DEFF Research Database (Denmark)

    Oellgaard, Jens; Gæde, Peter; Rossing, Peter

    2016-01-01

    -label trial. Duration of the intervention was 8 years, where after all patients were recommended intensified treatment. Total follow-up of up to 21 years of 24 hour urinary albumin excretion rate and GFR (51Cr-EDTA-clearance) assessed at 6 study visits. Information on end stage renal disease (ESRD......) and mortality was obtained from national registries. Outcome measures were progression to macroalbuminuria (>300 mg/24h), decline-rates of GFR and progression to end stage renal disease (ESRD) or death. Results: Progression to macroalbuminuria was reduced in the original intensive-therapy group with a hazard...

  18. A comparative study of CaWO4 and rare earth intensifying screens

    International Nuclear Information System (INIS)

    Ambiger, T.Y.; Ayappan, P.

    1978-01-01

    Three brands of commercially available calcium tungstate intensifying screens and a brand of rare earth screen emitting blue light have been used with two types of fast medical x-ray films, one imported and the other indigenous in various film-screen combinations and their sensitometric properties have been determined and compared. The rare earth screen has been found to be about 3 to 4 times faster than the tungstate screens without reduction in contrast. This indicates that the use of rare earth screen in medical radiography will help to reduce the patient dose by the same factor. (M.G.B.)

  19. Diels–Alder reactions of myrcene using intensified continuous-flow reactors

    Directory of Open Access Journals (Sweden)

    Christian H. Hornung

    2017-01-01

    Full Text Available This work describes the Diels–Alder reaction of the naturally occurring substituted butadiene, myrcene, with a range of different naturally occurring and synthetic dienophiles. The synthesis of the Diels–Alder adduct from myrcene and acrylic acid, containing surfactant properties, was scaled-up in a plate-type continuous-flow reactor with a volume of 105 mL to a throughput of 2.79 kg of the final product per day. This continuous-flow approach provides a facile alternative scale-up route to conventional batch processing, and it helps to intensify the synthesis protocol by applying higher reaction temperatures and shorter reaction times.

  20. Effects of Intensifying Labor Market Programs on Post-Unemployment Wages: Evidence From a Controlled Experiment

    DEFF Research Database (Denmark)

    Sørensen, Kenneth Lykke

    This paper investigates effects on wages of a Danish field experiment intensifying Active Labor Market Policies (ALMP).We link unemployed workers who participated in an ALMP experiment called “Quickly Back” carried out by the Danish Ministry of Employment 2005-2006 in two counties to matched...... employer-employee and public transfer register data up to 2008 enabling us to analyze exact labor market transitions and jobs of the participants. Men in one of the counties experienced significant higher probability of earning higher short and long term wages after treatment. Treated men in the other...

  1. Detection matrix of an electromagnetic radiation and radiological image intensifier comprising such a matrix

    International Nuclear Information System (INIS)

    Fraleux, Jean.

    1982-01-01

    This invention concerns a detection matrix comprising, in an electrode lattice of lines and columns, addressing means constituted of thin film technology MOS transistors and photoconductances which enable the number of unit module crossings to be halved and to bring about an increase in the effective detection area. This detection matrix is employed in radiological image intensifiers where it ensures the conversion of incident X photons into reading electric signals or only the detection of a visible radiation in the case where the incident X photons are converted into lesser energy photons by a scintillator. The scintillator is then formed of a panel brought into contact with the detector mosaic [fr

  2. Design and analysis of a flux intensifying permanent magnet embedded salient pole wind generator

    Science.gov (United States)

    Guo, Yujing; Jin, Ping; Lin, Heyun; Yang, Hui; Lyu, Shukang

    2018-05-01

    This paper presents an improved flux intensifying permanent magnet embedded salient pole wind generator (FI-PMESPWG) with mirror symmetrical magnetizing directions permanent magnet (PM) for improving generator's performances. The air-gap flux densities, the output voltage, the cogging torque and the d- and q-axis inductances of FI-PMESPWG are all calculated and analyzed by using the finite element method (FEM). To highlight the advantages of the proposed FI-PMESPWG, an original permanent magnet embedded salient pole wind generator (PMESPWG) model is adopted for comparison under the same operating conditions. The calculating results show that the air-gap flux densities of FI-PMESPWG are intensified with the same magnet amounts because the PMs are set in a form of V shape in each pole. The difference between d-axis inductance and q-axis inductance of the proposed FI-PMESPWG is reduced. Thus, the output power of the proposed FI-PMESPWG reaches a higher value than that of the original PMESPWG at the same current phase angle. The cogging torque is diminished because the flux path is changed. All the analysis results indicate that the electromagnetic characteristics of the proposed FI-PMESPWG are significantly better than that of the original PMESPWG.

  3. Self-triggered image intensifier tube for high-resolution UHECR imaging detector

    CERN Document Server

    Sasaki, M; Jobashi, M

    2003-01-01

    The authors have developed a self-triggered image intensifier tube with high-resolution imaging capability. An image detected by a first image intensifier tube as an electrostatic lens with a photocathode diameter of 100 mm is separated by a half-mirror into a path for CCD readout (768x494 pixels) and a fast control to recognize and trigger the image. The proposed system provides both a high signal-to-noise ratio to improve single photoelectron detection and excellent spatial resolution between 207 and 240 mu m rendering this device a potentially essential tool for high-energy physics and astrophysics experiments, as well as high-speed photography. When combined with a 1-arcmin resolution optical system with 50 deg. field-of-view proposed by the present authors, the observation of ultra high-energy cosmic rays and high-energy neutrinos using this device is expected, leading to revolutionary progress in particle astrophysics as a complementary technique to traditional astronomical observations at multiple wave...

  4. Intensified Vegetation Water Use due to Soil Calcium Leaching under Acid Deposition

    Science.gov (United States)

    Lanning, M.; Wang, L.; Scanlon, T. M.; Vadeboncoeur, M. A.; Adams, M. B.; Epstein, H. E.; Druckenbrod, D.

    2017-12-01

    Despite the important role vegetation plays in the global water cycle, the exact controls of vegetation water use, especially the role of soil biogeochemistry, remain elusive. Nitrate and sulfate deposition from fossil fuel burning has caused significant soil acidification, leading to the leaching of soil base cations. From a physiological perspective, plants require various soil cations as signaling and regulatory ions as well as integral parts of structural molecules; a depletion of soil cations can cause reduced productivity and abnormal responses to environmental change. A deficiency in calcium could also potentially prolong stomatal opening, leading to increased transpiration until enough calcium had been acquired to stimulate stomatal closure. Based on the plant physiology and the nature of acidic deposition, we hypothesize that depletion of the soil calcium supply, induced by acid deposition, would intensify vegetation water use at the watershed scale. We tested this hypothesis by analyzing a long-term and unique data set (1989-2012) of soil lysimeter data along with stream flow and evapotranspiration data at the Fernow Experimental Forest. We show that depletion of soil calcium by acid deposition can intensify vegetation water use ( 10% increase in evapotranspiration and depletion in soil water) for the first time. These results are critical to understanding future water availability, biogeochemical cycles, and surficial energy flux and may help reduce uncertainties in terrestrial biosphere models.

  5. Design and test of a high resolution plastic scintillating fiber detector with intensified CCD readout

    International Nuclear Information System (INIS)

    Rebourgeard, P.

    1991-01-01

    We present the design of a particle detector involving a coherent array of 100 000 plastic scintillating microfibers, with an individual core diameter around 50 micrometers, and an intensified bidimensional CCD array. We investigate both theoretically and experimentally the use of polystyrene based scintillators in optical multimodal fibers. The isotropic excitation of modes and the characteristics of energy transfers between the polystyrene matrix and the added fluorescent dyes are of particular interest. An experimental approach is proposed and applied to the development of a new binary scintillator. In order to study the transmission of the signal from the interaction area to the output face, we specify the loss factors, the resolution and the signal to noise ratio within the fiber array. The low light level at the output face of the detector leads us to use image intensifiers in photon counting mode. This requires a detailed analysis of resolutions, gain, noise and detectivity concepts. We propose to describe these strongly correlated notions by the moment generation formalism. Thus, a previous modelisation of the photoelectronic devices allows us to evaluate the performance of the readout chain. A complete detector has been assembled and tested on a high energy hadron beam; the measurements are in good agreement with the modelisation [fr

  6. How do Rumination and Social Problem Solving Intensify Depression? A Longitudinal Study.

    Science.gov (United States)

    Hasegawa, Akira; Kunisato, Yoshihiko; Morimoto, Hiroshi; Nishimura, Haruki; Matsuda, Yuko

    2018-01-01

    In order to examine how rumination and social problem solving intensify depression, the present study investigated longitudinal associations among each dimension of rumination and social problem solving and evaluated aspects of these constructs that predicted subsequent depression. A three-wave longitudinal study, with an interval of 4 weeks between waves, was conducted. Japanese university students completed the Beck Depression Inventory-Second Edition, Ruminative Responses Scale, Social Problem-Solving Inventory-Revised Short Version, and Interpersonal Stress Event Scale on three occasions 4 weeks apart ( n  = 284 at Time 1, 198 at Time 2, 165 at Time 3). Linear mixed models were analyzed to test whether each variable predicted subsequent depression, rumination, and each dimension of social problem solving. Rumination and negative problem orientation demonstrated a mutually enhancing relationship. Because these two variables were not associated with interpersonal conflict during the subsequent 4 weeks, rumination and negative problem orientation appear to strengthen each other without environmental change. Rumination and impulsivity/carelessness style were associated with subsequent depressive symptoms, after controlling for the effect of initial depression. Because rumination and impulsivity/carelessness style were not concurrently and longitudinally associated with each other, rumination and impulsive/careless problem solving style appear to be independent processes that serve to intensify depression.

  7. Performance in sports--With specific emphasis on the effect of intensified training.

    Science.gov (United States)

    Bangsbo, J

    2015-12-01

    Performance in most sports is determined by the athlete's technical, tactical, physiological and psychological/social characteristics. In the present article, the physical aspect will be evaluated with a focus on what limits performance, and how training can be conducted to improve performance. Specifically how intensified training, i.e., increasing the amount of aerobic high-intensity and speed endurance training, affects physiological adaptations and performance of trained subjects. Periods of speed endurance training do improve performance in events lasting 30 s-4 min, and when combined with aerobic high-intensity sessions, also performance during longer events. Athletes in team sports involving intense exercise actions and endurance aspects, such as soccer and basketball, can also benefit from intensified training. Speed endurance training does reduce energy expenditure and increase expression of muscle Na(+), K(+) pump α subunits, which may preserve muscle cell excitability and delay fatigue development during intense exercise. When various types of training are conducted in the same period (concurrent training), as done in a number of sports, one type of training may blunt the effect of other types of training. It is not, however, clear how various training modalities are affecting each other, and this issue should be addressed in future studies. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  8. X-ray image intensifier tube and radiographic camera incorporating same

    International Nuclear Information System (INIS)

    1981-01-01

    An X-ray sensitive image intensifier tube is described. It has an input window comprising at least one of iron, chromium and nickel for receiving an X-ray image. There is a flat scintillator screen adjacent for converting the X-ray image into a light pattern image. Adjacent to this is a flat photocathode layer for emitting photoelectrons in a pattern corresponding to the light pattern image. Parallel to this and spaced from it is a flat phosphor display screen. Electrostatic voltage is applied to the display screen and the photocathode layer to create an electric field between them to accelerate the photoelectrons towards the display screen. The paths of such parallel straight trajectories are governed solely by the electrostatic voltage applied, the image at the display screen being substantially equal in size to that of the X-ray image received at the input window. The tube envelope is preferably metallic to enable the basic components to be kept at a neutral potential and avoid spurious emissions. A radiographic camera with such an intensifier tube is also described. (U.K.)

  9. X-ray topography with scintillators coupled to image intensifiers or camera tubes

    International Nuclear Information System (INIS)

    Beauvais, Yves; Mathiot, Alain.

    1978-01-01

    The possibility of imaging topographic figures in real time by using a thin scintillator coupled to either a high-gain image intensifier or a camera tube is investigated. The camera tube must have a high gain because of the low photon fluxes that are encountered in practice, and because of the relatively low quantum yield of thin phosphors. With conventional X-ray generators, the resolution is photon-noise limited. With more powerful generators like synchrotrons, real-time imaging appears possible, and the resolution is limited by the modulation transfer function of the image tube. Higher resolution can be reached by increasing the magnification between the screen and the image tube. When doing so, the input field is reduced and thinner phosphor screens must be used, resulting in a lower yield. Each time the magnification is doubled, the minimum required photon flux is multiplier by about 8, so that the advantages of increasing the magnification are rapidly limited, so far as real-time imaging is concerned. Because image tube resolution is mainly limited by the modulation transfer function of the phosphor for image intensifiers, and by that of the target for camera tubes, improvement of photocathode resolution can be obtained by magnifying electron optics. A zooming electron optic would permit the field and the resolution of the tube to be adapted to the observed subject. Unfortunately such tubes do not exist at present for this type of application, and in the required size

  10. Cheap streak camera based on the LD-S-10 intensifier tube

    Science.gov (United States)

    Dashevsky, Boris E.; Krutik, Mikhail I.; Surovegin, Alexander L.

    1992-01-01

    Basic properties of a new streak camera and its test results are reported. To intensify images on its screen, we employed modular G1 tubes, the LD-A-1.0 and LD-A-0.33, enabling magnification of 1.0 and 0.33, respectively. If necessary, the LD-A-0.33 tube may be substituted by any other image intensifier of the LDA series, the choice to be determined by the size of the CCD matrix with fiber-optical windows. The reported camera employs a 12.5- mm-long CCD strip consisting of 1024 pixels, each 12 X 500 micrometers in size. Registered radiation was imaged on a 5 X 0.04 mm slit diaphragm tightly connected with the LD-S- 10 fiber-optical input window. Electrons escaping the cathode are accelerated in a 5 kV electric field and focused onto a phosphor screen covering a fiber-optical plate as they travel between deflection plates. Sensitivity of the latter was 18 V/mm, which implies that the total deflecting voltage was 720 V per 40 mm of the screen surface, since reversed-polarity scan pulses +360 V and -360 V were applied across the deflection plate. The streak camera provides full scan times over the screen of 15, 30, 50, 100, 250, and 500 ns. Timing of the electrically or optically driven camera was done using a 10 ns step-controlled-delay (0 - 500 ns) circuit.

  11. Large-image intensifier photofluorography and conventional radiography in pulmonary emphysema

    International Nuclear Information System (INIS)

    Manninen, H.; Partanen, K.; Soimakallio, S.; Rytkoenen, H.

    1988-01-01

    Large-screen image intensifier (II) photofluorography was compared with full-size screen-film chest radiography in the diagnosis of pulmonary emphysema in 84 patients. Photospot films and conventional radiographs were interpreted independently by three radiologists. Computed tomography (CT) was used as an independent reference technique, and diagnostic performance of chest radiography in various CT patterns of emphysema was evaluated. The difference in diagnostic sensitivity for emphysema in favor of conventional chest radiography over photofluorography (0.65 versus 0.56) was statistically significant (p < 0.05). Specificity of the imaging modalities was equal: 0.78 in full-size films and 0.77 in photospot films. All CT patterns of emphysema had great false negative response rates in chest radiography, which is an inaccurate technique for the diagnosis of emphysema. CT is required for reliable radiologic evaluation of emphysema. (orig.)

  12. Radial-pulse propagation and impedance characteristics of optically shuttered channel intensifier tubes

    International Nuclear Information System (INIS)

    Detch, J.L. Jr.; Noel, B.W.

    1981-01-01

    Electrically gated proximity-focused channel intensifier tubes are often used as optical shutters. Optimum nanosecond shuttering requires both understanding the electrical pulse propagation across the device structure and proper impedance matching. A distributed-transmission-line model is developed that describes analytically the voltage- and current-wave propagation characteristics as functions of time for any point on the surface. The optical gain's spatial uniformity and shutter-open times are shown to depend on the electrical pulse width and amplitude, and on the applied bias. The driving-point impedance is derived from the model and is expressed as a function of an infinite sum of terms in the complex frequency. The synthesis in terms of lumped-constant network elements is realized in first- and second-Foster equivalent circuits. Experimental impedance data are compared with the model's predictions and deviations from the ideal model are discussed

  13. Nanoparticles generated by laser in liquids as contrast medium and radiotherapy intensifiers

    Science.gov (United States)

    Restuccia, Nancy; Torrisi, Lorenzo

    2018-01-01

    The synthesis of Au and Ag nanoparticles (NP) though laser ablation in liquids as a function the laser parameters is presented. Spherical NPs with diameter distribution within 1 and 100 nm were prepared by laser ablation in water. The nanoparticles characterization was performed using optical spectroscopy and electronic microscopy (SEM and TEM) measurements. Studies of the possible use of metallic nanoparticles as intensifier of diagnostics imaging contrast medium and absorbing dose from ionizing radiations in traditional radiotherapy and protontherapy are presented. Examples of in vitro (in tissue equivalent materials) and in vivo (in mice), were conducted thank to simulation programs permitting to evaluate the enhancement of efficiency in imaging and therapy as a function of the NPs concentrations and irradiation conditions.

  14. Nanoparticles generated by laser in liquids as contrast medium and radiotherapy intensifiers

    Directory of Open Access Journals (Sweden)

    Restuccia Nancy

    2018-01-01

    Full Text Available The synthesis of Au and Ag nanoparticles (NP though laser ablation in liquids as a function the laser parameters is presented. Spherical NPs with diameter distribution within 1 and 100 nm were prepared by laser ablation in water. The nanoparticles characterization was performed using optical spectroscopy and electronic microscopy (SEM and TEM measurements. Studies of the possible use of metallic nanoparticles as intensifier of diagnostics imaging contrast medium and absorbing dose from ionizing radiations in traditional radiotherapy and protontherapy are presented. Examples of in vitro (in tissue equivalent materials and in vivo (in mice, were conducted thank to simulation programs permitting to evaluate the enhancement of efficiency in imaging and therapy as a function of the NPs concentrations and irradiation conditions.

  15. Lead foil in dental X-ray film: Backscattering rejection or image intensifier?

    International Nuclear Information System (INIS)

    Hönnicke, M.G.; Delben, G.J.; Godoi, W.C.; Swinka-Filho, V.

    2014-01-01

    Dental X-ray films are still largely used due to sterilization issues, simplicity and, mainly, economic reasons. These films almost always are double coated (double emulsion) and have a lead foil in contact with the film for X-ray backscattering rejection. Herein we explore the use of the lead foil as an image intensifier. In these studies, spatial resolution was investigated when images were acquired on the dental X-ray films with and without the lead foil. Also, the lead foil was subjected to atomic analysis (fluorescent measurements) and structure analysis (X-ray diffraction). We determined that the use of the lead foil reduces the exposure time, however, does not affect the spatial resolution on the acquired images. This suggests that the fluorescent radiation spread is smaller than the grain sizes of the dental X-ray films

  16. Lead foil in dental X-ray film: Backscattering rejection or image intensifier?

    Science.gov (United States)

    Hönnicke, M. G.; Delben, G. J.; Godoi, W. C.; Swinka-Filho, V.

    2014-11-01

    Dental X-ray films are still largely used due to sterilization issues, simplicity and, mainly, economic reasons. These films almost always are double coated (double emulsion) and have a lead foil in contact with the film for X-ray backscattering rejection. Herein we explore the use of the lead foil as an image intensifier. In these studies, spatial resolution was investigated when images were acquired on the dental X-ray films with and without the lead foil. Also, the lead foil was subjected to atomic analysis (fluorescent measurements) and structure analysis (X-ray diffraction). We determined that the use of the lead foil reduces the exposure time, however, does not affect the spatial resolution on the acquired images. This suggests that the fluorescent radiation spread is smaller than the grain sizes of the dental X-ray films.

  17. Stepping back to advance: Why IGD needs an intensified debate instead of a consensus.

    Science.gov (United States)

    Quandt, Thorsten

    2017-06-01

    Based on their analysis of Internet gaming disorder (IGD) criteria, Kuss, Griffiths, and Pontes (2017) come to the conclusion that the current situation can be described as "chaos and confusion." Their assessment is not an exaggeration. It can be argued that there are even more issues, on logical/definitional and political/social levels: (a) the IGD diagnosis is lacking a well-defined object, (b) the cause and effect cannot be differentiated outside lab conditions, (c) the social and political effects of declaring a social behavior as a disease are worrying, and (d) a rushed diagnosis may construct an addiction with potentially harmful effects on (formerly) healthy populations. Instead of closing the debate by declaring a consensus and codifying IGD in the DSM, an undogmatic, intensified, and broader discussion is needed.

  18. Are the Satellite-Observed Narrow, Streaky Chlorophyll Filaments Locally Intensified by the Submesoscale Processes?

    Science.gov (United States)

    2015-11-05

    HIS I’OR’A CANCELS AND SUPERSEOFS Al l PRFV•OUS VERSIONS ARE THE SATELLITE-OBSERVED NARROW, STREAKY CHLOROPHYLL FILAMENTS LOCALLY INTENSIFIED BY...AUGUST 2003 cold, dense jeto C 17 16 15 14 13 122.4W 122W 122.4W 122W warm, anticyclonic eddy CHLOROPHYLL 122.4W 122W 122.4W 122W 122.4W 122W filament...122.4W 122W mg/m 3 10 4 2 1 0.4 0.2 Figure 1. MODIS-Aqua SST and Chlorophyll a images for August 2003. Black lines on MODIS SST and Chlorophyll a

  19. Correlated observations of intensified whistler waves and electron acceleration around the geostationary orbit

    International Nuclear Information System (INIS)

    Xiao Fuliang; He Zhaoguo; Tang Lijun; Zong Qiugang; Wang Chengrui; Su Zhenpeng

    2012-01-01

    We report correlated observations of enhanced whistler waves and energetic electron acceleration collected by multiple satellites specifically near the geostationary orbit during the 7–10 November 2004 superstorms, together with multi-site observations of ULF wave power measured on the ground. Energetic (>0.6 MeV) electron fluxes are found to increase significantly during the recovery phase, reaching a peak value by ∼100 higher than the prestorm level. In particular, such high electron flux corresponds to intensified whistler wave activities but to the weak ULF wave power. This result suggests that wave–particle interaction appears to be more important than inward radial diffusion in acceleration of outer radiation belt energetic electrons in this event, assisting to better understand the acceleration mechanism. (paper)

  20. Has the Competition among Professions in the Nordic Welfare States Intensified? A Danish Case

    Directory of Open Access Journals (Sweden)

    John Storm Pedersen

    2014-06-01

    Full Text Available Has the competition among professions in the Nordic welfare states intensified in recent decades? Yes, and in a manner that has resulted in predictable classic struggles and conflicts among professions. We argue that the struggles and conflicts that arise translate into insufficient provision of welfare services for taxpayers’ money. To avoid this predicament, further developing co-operation among professions is important. Public managers, as argued in this article using a Danish case, play a significant role in achieving this. The Danish case studied shows how some public managers, in their efforts to create co-operation among professions, have developed a modern, dialogue-based management technique built on dialectical refutation, similar to Socratic elenchus.

  1. Matrix based method for synthesis of main intensified and integrated distillation sequences

    International Nuclear Information System (INIS)

    Khalili-Garakani, Amirhossein; Kasiri, Norollah; Ivakpour, Javad

    2016-01-01

    The objective of many studies in this area has involved access to a column-sequencing algorithm enabling designers and researchers alike to generate a wide range of sequences in a broad search space, and be as mathematically and as automated as possible for programing purposes and with good generality. In the present work an algorithm previously developed by the authors, called the matrix method, has been developed much further. The new version of the algorithm includes thermally coupled, thermodynamically equivalent, intensified, simultaneous heat and mass integrated and divided-wall column sequences which are of gross application and provide vast saving potential both on capital investment, operating costs and energy usage in industrial applications. To demonstrate the much wider searchable space now accessible, a three component separation has been thoroughly examined as a case study, always resulting in an integrated sequence being proposed as the optimum.

  2. A model-based framework for design of intensified enzyme-based processes

    DEFF Research Database (Denmark)

    Román-Martinez, Alicia

    This thesis presents a generic and systematic model-based framework to design intensified enzyme-based processes. The development of the presented methodology was motivated by the needs of the bio-based industry for a more systematic approach to achieve intensification in its production plants...... in enzyme-based processes which have found significant application in the pharmaceutical, food, and renewable fuels sector. The framework uses model-based strategies for (bio)-chemical process design and optimization, including the use of a superstructure to generate all potential reaction......(s)-separation(s) options according to a desired performance criteria and a generic mathematical model represented by the superstructure to derive the specific models corresponding to a specific process option. In principle, three methods of intensification of bioprocess are considered in this thesis: 1. enzymatic one...

  3. [New intensifying screens in clinical radiology. II. Examinations in clinical practice].

    Science.gov (United States)

    Freyschmidt, J; Saure, D; Hagemann, G

    1976-09-01

    A clinically applicable procedure for testing new intensifying rare earth screens, as well as the special Siemens' screen is described. The results are related to universal screens. The film-screen combination alpha 4XD (gadolinium oxysulphide with normal, green sensitive film) results in a reduction of radiation dose to half with detail comparable with universal screens. The Siemens' special screen has similar advantages. Screens with a higher intensification factor and reduction of the mAs to one sixth results in loss of detail. This does not necessarily reduce their clinical use if they are used for appropriate purposes. The results of this clinically orientated technique agreed well with physically objective methods using lead grids. The advantages of the new screens are discussed in terms of their practical application.

  4. Performance in sports - with specific emphasis on the effect of intensified training

    DEFF Research Database (Denmark)

    Bangsbo, Jens

    2015-01-01

    Performance in most sports is determined by the athlete's technical, tactical, physiological and psychological/social characteristics. In the present article, the physical aspect will be evaluated with a focus on what limits performance, and how training can be conducted to improve performance...... with aerobic high-intensity sessions, also performance during longer events. Athletes in team sports involving intense exercise actions and endurance aspects, such as soccer and basketball, can also benefit from intensified training. Speed endurance training does reduce energy expenditure and increase...... expression of muscle Na(+) , K(+) pump α subunits, which may preserve muscle cell excitability and delay fatigue development during intense exercise. When various types of training are conducted in the same period (concurrent training), as done in a number of sports, one type of training may blunt the effect...

  5. Influence of veiling glare in the image intensifier on cinefluorographic sensitometry

    International Nuclear Information System (INIS)

    Matsuda, Eiji; Sanada, Taizo; Hitomi, Go; Ishii, Koushi; Yoshida, Akira

    1998-01-01

    We have experienced variations in the shape of the cinesensitometric curve when the exposure field is greatly altered. The veiling glare that arises from the scattering of x-ray photons, electrons, and light in the x-ray image intensifier (X-I.I.) depends on the size of the exposure field. Also, the effect of adjacent chemicals that occurs during the development process depends on the size of the exposed area on film. The veiling glare in the X-I.I. and the adjacent chemical effect on cine film processing may be responsible for these phenomena. This study investigated the influences of veiling glare on the shape of the cinesensitometric curve. Results showed that the veiling glare of the X-I.I. acts to increase the sensitivity of the cinesensitometric curve on the X-I.I. when the exposed area on the X-I.I. is larger. (author)

  6. Influence of veiling glare in the image intensifier on cinefluorographic sensitometry

    Energy Technology Data Exchange (ETDEWEB)

    Matsuda, Eiji; Sanada, Taizo; Hitomi, Go; Ishii, Koushi [Kawasaki Medical School, Kurashiki, Okayama (Japan). Hospital; Yoshida, Akira

    1998-08-01

    We have experienced variations in the shape of the cinesensitometric curve when the exposure field is greatly altered. The veiling glare that arises from the scattering of x-ray photons, electrons, and light in the x-ray image intensifier (X-I.I.) depends on the size of the exposure field. Also, the effect of adjacent chemicals that occurs during the development process depends on the size of the exposed area on film. The veiling glare in the X-I.I. and the adjacent chemical effect on cine film processing may be responsible for these phenomena. This study investigated the influences of veiling glare on the shape of the cinesensitometric curve. Results showed that the veiling glare of the X-I.I. acts to increase the sensitivity of the cinesensitometric curve on the X-I.I. when the exposed area on the X-I.I. is larger. (author)

  7. A distortion correction method for image intensifier and electronic portal images used in radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Ioannidis, G T; Geramani, K N; Zamboglou, N [Strahlenklinik, Stadtische Kliniken Offenbach, Offenbach (Germany); Uzunoglu, N [Department of Electrical and Computer Engineering, National Technical University of Athens, Athens (Greece)

    1999-12-31

    At the most of radiation departments a simulator and an `on line` verification system of the treated volume, in form of an electronic portal imaging device (EPID), are available. Networking and digital handling (saving, archiving etc.) of the image information is a necessity in the image processing procedures in order to evaluate verification and simulation recordings at the computer screen. Distortion is on the other hand prerequisite for quantitative comparison of both image modalities. Another limitation factor, in order to make quantitative assertions, is the fact that the irradiation fields in radiotherapy are usually bigger than the field of view of an image intensifier. Several segments of the irradiation field must therefore be acquired. Using pattern recognition techniques these segments can be composed into a single image. In this paper a distortion correction method will be presented. The method is based upon a well defined Grid which is embedded during the registration process on the image. The video signal from the image intensifier is acquired and processed. The grid is then recognised using image processing techniques. Ideally if all grid points are recognised, various methods can be applied in order to correct the distortion. But in practice this is not the case. Overlapping structures (bones etc.) have as a consequence that not all of the grid points can be recognised. Mathematical models from the Graph theory are applied in order to reconstruct the whole grid. The deviation of the grid points positions from the rated value is then used to calculate correction coefficients. This method (well defined grid, grid recognition, correction factors) can also be applied in verification images from the EPID or in other image modalities, and therefore a quantitative comparison in radiation treatment is possible. The distortion correction method and the application on simulator images will be presented. (authors)

  8. The visible intensified cameras for plasma imaging in the TJ-II stellarator

    International Nuclear Information System (INIS)

    Cal, E. de la; Carralero, D.; Pablos, J.L. de; Alonso, A.; Rios, L.; Garcia Sanchez, P.; Hidalgo, C.

    2011-01-01

    Visible cameras are widely used in fusion experiments for diagnosis and for machine safety issues. They are generally used to monitor the plasma emission, but are also sensible to surface Blackbody radiation and Bremsstrahlung. Fast or high speed cameras capable of operating in the 10 5 frames per second speed range are today commercially available and offer the opportunity to plasma fusion researchers of two-dimensional (2D) imaging of fast phenomena such as turbulence, ELMs, disruptions, dust, etc. The tracking of these fast phenomena requires short exposure times down to the μ s range and the light intensity can be often near the signal to noise ratio limit especially in low plasma emission regions such as the far SOL Additionally, when using interference filters to monitor, e.g. impurity line emission, the photon flux is strongly reduced and the emission cannot be imaged at high speed. Therefore, the use of image intensifiers that amplify the light intensity onto the camera sensor can be of great help. The present work describes the use of intensifiers in the visible fast cameras of TJ-II stellarator. We have achieved spectroscopic plasma imaging of filtered impurity atomic line emission at short exposure times down to the 10 μ s range depending on atomic line and concentration. Additionally, plasma movies at velocities of 2x10 5 frames per second near the camera operation limit can be recorded with exposure times well below 1 μ s with sufficient signal to noise ratio. Although an increasing degradation of the image quality appears when raising the light amplification, an effective gain of up to two orders of magnitude of the light intensity is feasible for many applications (copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  9. The visible intensified cameras for plasma imaging in the TJ-II stellarator

    Energy Technology Data Exchange (ETDEWEB)

    Cal, E. de la; Carralero, D.; Pablos, J.L. de; Alonso, A.; Rios, L.; Garcia Sanchez, P.; Hidalgo, C. (Laboratorio Nacional de Fusion, Asociacion Euratom-Ciemat, Av. Complutense 22, E-28040 Madrid)

    2011-09-15

    Visible cameras are widely used in fusion experiments for diagnosis and for machine safety issues. They are generally used to monitor the plasma emission, but are also sensible to surface Blackbody radiation and Bremsstrahlung. Fast or high speed cameras capable of operating in the 10{sup 5} frames per second speed range are today commercially available and offer the opportunity to plasma fusion researchers of two-dimensional (2D) imaging of fast phenomena such as turbulence, ELMs, disruptions, dust, etc. The tracking of these fast phenomena requires short exposure times down to the {mu} s range and the light intensity can be often near the signal to noise ratio limit especially in low plasma emission regions such as the far SOL Additionally, when using interference filters to monitor, e.g. impurity line emission, the photon flux is strongly reduced and the emission cannot be imaged at high speed. Therefore, the use of image intensifiers that amplify the light intensity onto the camera sensor can be of great help. The present work describes the use of intensifiers in the visible fast cameras of TJ-II stellarator. We have achieved spectroscopic plasma imaging of filtered impurity atomic line emission at short exposure times down to the 10 {mu} s range depending on atomic line and concentration. Additionally, plasma movies at velocities of 2x10{sup 5} frames per second near the camera operation limit can be recorded with exposure times well below 1 {mu} s with sufficient signal to noise ratio. Although an increasing degradation of the image quality appears when raising the light amplification, an effective gain of up to two orders of magnitude of the light intensity is feasible for many applications (copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  10. Reduced risk of heart failure with intensified multifactorial intervention in individuals with type 2 diabetes and microalbuminuria

    DEFF Research Database (Denmark)

    Oellgaard, Jens; Gæde, Peter; Rossing, Peter

    2018-01-01

    of hospitalisation for heart failure. METHODS: One hundred and sixty individuals were randomised to conventional or intensified multifactorial intervention, using sealed envelopes. The trial was conducted using the Prospective, Randomised, Open, Blinded Endpoints (PROBE) design. After 7.8 years, all individuals were......AIMS/HYPOTHESIS: In type 2 diabetes mellitus, heart failure is a frequent, potentially fatal and often forgotten complication. Glucose-lowering agents and adjuvant therapies modify the risk of heart failure. We recently reported that 7.8 years of intensified compared with conventional...... offered intensified therapy and the study continued as an observational follow-up study for an additional 13.4 years. Heart-failure hospitalisations were adjudicated from patient records by an external expert committee blinded for treatment allocation. Event rates were compared using a Cox regression...

  11. SIgA response and incidence of upper respiratory tract infections during intensified training in youth basketball players.

    Science.gov (United States)

    Moraes, H; Aoki, M S; Freitas, C G; Arruda, Afs; Drago, G; Moreira, A

    2017-03-01

    The aim of the present study was to examine the effect of an intensified training phase followed by a tapering phase on the salivary immunoglobulin A concentration and on the upper respiratory tract infection (URTI) symptoms in young male basketball players. The session rating of perceived exertion method was used to quantify the internal training load, and the Wisconsin Upper Respiratory Symptom Survey-21 questionnaire was used to assess URTI symptoms. The Yo-Yo IR1 test and saliva collection were carried out at the beginning of the study (T1), after the intensified phase (T2), and after tapering (T3). A higher internal training load was observed for the intensified phase compared with the tapering phase (t=19.10; ptraining load followed by a tapering period negatively affects the mucosal immune function with no significant change in severity of URTI in young basketball players.

  12. Possibilities of reducing radiation doses in spinograms of adolescents by means of most intensifying screens and compensating screens

    Energy Technology Data Exchange (ETDEWEB)

    Pollaehne, W; Brandt, G A [Staedtisches Klinikum Berlin-Buch (German Democratic Republic)

    1980-01-01

    Most intensifying screens based on CaWO/sub 4/ and LaOBr/sub 2/ or combinations of them were used in radiography of both the thoracic and the lumbar parts of the spines of adolescents. The results obtained were compared with those achieved by means of screens usually used for spinograms. Radiation exposure was reduced, on an average by 30-40%, when most intensifying screens were used, the image quality being the same. The introduction of high-speed superscreens is pressingly recommended.

  13. Advances in Gamma-Ray Imaging with Intensified Quantum-Imaging Detectors

    Science.gov (United States)

    Han, Ling

    Nuclear medicine, an important branch of modern medical imaging, is an essential tool for both diagnosis and treatment of disease. As the fundamental element of nuclear medicine imaging, the gamma camera is able to detect gamma-ray photons emitted by radiotracers injected into a patient and form an image of the radiotracer distribution, reflecting biological functions of organs or tissues. Recently, an intensified CCD/CMOS-based quantum detector, called iQID, was developed in the Center for Gamma-Ray Imaging. Originally designed as a novel type of gamma camera, iQID demonstrated ultra-high spatial resolution (advancing this conceptually-proven gamma-ray imaging technology to make it ready for both preclinical and clinical applications. To start with, a Monte Carlo simulation of the key light-intensification device, i.e. the image intensifier, was developed, which revealed the dominating factor(s) that limit energy resolution performance of the iQID cameras. For preclinical imaging applications, a previously-developed iQID-based single-photon-emission computed-tomography (SPECT) system, called FastSPECT III, was fully advanced in terms of data acquisition software, system sensitivity and effective FOV by developing and adopting a new photon-counting algorithm, thicker columnar scintillation detectors, and system calibration method. Originally designed for mouse brain imaging, the system is now able to provide full-body mouse imaging with sub-350-micron spatial resolution. To further advance the iQID technology to include clinical imaging applications, a novel large-area iQID gamma camera, called LA-iQID, was developed from concept to prototype. Sub-mm system resolution in an effective FOV of 188 mm x 188 mm has been achieved. The camera architecture, system components, design and integration, data acquisition, camera calibration, and performance evaluation are presented in this work. Mounted on a castered counter-weighted clinical cart, the camera also features

  14. Influence of an intensified competition on fatigue and match performance in junior rugby league players.

    Science.gov (United States)

    Johnston, Rich D; Gabbett, Tim J; Jenkins, David G

    2013-09-01

    The aim of this study was to assess the physiological responses to an intensified rugby league competition and explore the relationships between fatigue and match performance. Prospective cohort study. Fifteen junior rugby league players (n=8 forwards, 7 backs; mean±SE, age 16.6±0.2 years; body mass 81.6±3.0kg; and height 178.9±1.8cm) competed in five 40min games over 5 days (two games each on days 1 and 2, one game on day 4, and no games on days 3 and 5). Over the competition, players performed a countermovement jump to assess neuromuscular fatigue, provided a fingertip blood sample to measure blood creatine kinase, and completed a questionnaire to monitor perceived wellbeing; ratings of perceived effort were recorded following each game. Global positioning system and video analysis of each game were used to assess match performance. Over the first 3 days, there were progressive and large increases in neuromuscular fatigue which peaked 12h after game 4 (forwards ES=4.45, p=0.014; backs ES=3.62, p=0.029), and muscle damage which peaked 1h post game 4 (forwards ES=4.45, p=0.004; backs ES=3.94 p=0.012), as well as reductions in perceived wellbeing. These measures gradually recovered over the final 2 days of the competition. Compared to the backs, the forwards experienced greater increases in creatine kinase following game 2 (ES=1.30) and game 4 (ES=1.24) and reductions in perceived wellbeing (ES=0.25-0.46). Match intensity, high-speed running, and repeated-high intensity effort bouts decreased in games 4 and 5 of the competition. Small to large associations were observed between the changes in fatigue, muscle damage and match performance, with significant correlations between creatine kinase and repeated high-intensity effort bout number (r=-0.70, p=0.031) and frequency (r=0.74, p=0.002) and low-speed activity (r=-0.56, p=0.029). Fatigue and muscle damage accumulate over an intensified competition, which is likely to contribute to reductions in high

  15. Psychological effects of the intensified follow-up of the CEAwatch trial after treatment for colorectal cancer

    NARCIS (Netherlands)

    Zhan, Zhuozhao; Verberne, Charlotte J.; van den Heuvel, Edwin R.; Grossmann, Irene; Ranchor, Adelita V.; Wiggers, Theo; de Bock, Geertruida H.

    2017-01-01

    Background: The aim of the study was to evaluate psychological effects of the state-of-art intensified follow-up protocol for colorectal cancer patients in the CEAwatch trial. Method: At two time points during the CEAwatch trial questionnaires regarding patients' attitude towards follow-up,

  16. Effect of intensified training on muscle ion kinetics, fatigue development and repeated short term performance in endurance trained cyclists

    DEFF Research Database (Denmark)

    Gunnarsson, Thomas Gunnar Petursson; Christensen, Peter Møller; Thomassen, Martin

    2013-01-01

    The effects of intensified training in combination with a reduced training volume on muscle ion kinetics, transporters and work capacity were examined. Eight well-trained cyclists replaced their regular training with speed-endurance training (12x30-s sprints) 2-3 times per wk and aerobic high...

  17. High incidence of pseudotumours after hip resurfacing even in low risk patients; results from an intensified MRI screening protocol.

    NARCIS (Netherlands)

    Weegen, W. van der; Smolders, J.M.; Sijbesma, T.; Hoekstra, H.J.; Brakel, K.; Susante, J.L.C. van

    2013-01-01

    We intensified our screening protocol for the presence of pseudotumours in a consecutive series of patients with a hip resurfacing arthroplasty (HRA), to establish whether we should be alert to the presence of 'silent' pseudotumours. Patients categorised with high risk (11 hips) and low risk (10

  18. A randomized trial of insulin aspart with intensified basal NPH insulin supplementation in people with Type 1 diabetes

    NARCIS (Netherlands)

    DeVries, J. H.; Lindholm, A.; Jacobsen, J. L.; Heine, R. J.; Home, P. D.

    2003-01-01

    Aims Insulin aspart has been shown to improve post-prandial and overall glycaemic control in people with Type 1 diabetes. We hypothesized that insulin aspart with intensified basal NPH insulin supplementation would result in better overall glycaemic control than human regular insulin with standard

  19. Intensified nitrogen and phosphorus removal in a novel electrolysis-integrated tidal flow constructed wetland system.

    Science.gov (United States)

    Ju, Xinxin; Wu, Shubiao; Zhang, Yansheng; Dong, Renjie

    2014-08-01

    A novel electrolysis-integrated tidal flow constructed wetland (CW) system was developed in this study. The dynamics of intensified nitrogen and phosphorus removal and that of hydrogen sulphide control were evaluated. Ammonium removal of up to 80% was achieved with an inflow concentration of 60 mg/L in wetland systems with and without electrolysis integration. Effluent nitrate concentration decreased from 2 mg/L to less than 0.5 mg/L with the decrease in current intensity from 1.5 mA/cm(2) to 0.57 mA/cm(2) in the electrolysis-integrated wetland system, thus indicating that the current intensity of electrolysis plays an important role in nitrogen transformations. Phosphorus removal was significantly enhanced, exceeding 95% in the electrolysis-integrated CW system because of the in-situ formation of a ferric iron coagulant through the electro-dissolution of a sacrificial iron anode. Moreover, the electrolyzed wetland system effectively inhibits sulphide accumulation as a result of a sulphide precipitation coupled with ferrous-iron electro-dissolution and/or an inhibition of bacterial sulphate reduction under increased aerobic conditions. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Probabilistic discrimination between large-scale environments of intensifying and decaying African Easterly Waves

    Energy Technology Data Exchange (ETDEWEB)

    Agudelo, Paula A. [Area Hidrometria e Instrumentacion Carrera, Empresas Publicas de Medellin, Medellin (Colombia); Hoyos, Carlos D.; Curry, Judith A.; Webster, Peter J. [School of Earth and Atmospheric Sciences, Georgia Institute of Technology, Atlanta, GA (United States)

    2011-04-15

    About 50-60% of Atlantic tropical cyclones (TCs) including nearly 85% of intense hurricanes have their origins as African Easterly Waves (AEWs). However, predicting the likelihood of AEW intensification remains a difficult task. We have developed a Bayesian diagnostic methodology to understand genesis of North Atlantic TCs spawned by AEWs through the examination of the characteristics of the AEW itself together with the large-scale environment, resulting in a probabilistic discrimination between large-scale environments associated with intensifying and decaying AEWs. The methodology is based on a new objective and automatic AEW tracking scheme used for the period 1980 to 2001 based on spatio-temporally Fourier-filtered relative vorticity and meridional winds at different levels and outgoing long wave radiation. Using the AEW and Hurricane Best Track Files (HURDAT) data sets, probability density functions of environmental variables that discriminate between AEWs that decay, become TCs or become major hurricanes are determined. Results indicate that the initial amplitude of the AEWs is a major determinant for TC genesis, and that TC genesis risk increases when the wave enters an environment characterized by pre-existing large-scale convergence and moist convection. For the prediction of genesis, the most useful variables are column integrated heating, vertical velocity and specific humidity, and a combined form of divergence and vertical velocity and SST. It is also found that the state of the large-scale environment modulates the annual cycle and interannual variability of the AEW intensification efficiency. (orig.)

  1. Intensifying the Casimir force between two silicon substrates within three different layers of materials

    International Nuclear Information System (INIS)

    Seyedzahedi, A.; Moradian, A.; Setare, M.R.

    2016-01-01

    We investigate the Casimir force for a system composed of two thick slabs as substrates within three different homogeneous layers. We use the scattering approach along with the Matsubara formalism in order to calculate the Casimir force at finite temperature. First, we focus on constructing the reflection matrices and then we calculate the Casimir force for a water–lipid system. According to the conventional use of silicon as a substrate, we apply the formalism to calculate the Casimir force for layers of Au, VO 2 , mica, KCl and foam rubber on the thick slabs of silicon. Afterwards, introducing an increasing factor, we compare our results with Lifshitz force in the vacuum between two semispaces of silicon in order to illustrate the influence of the layers on intensifying the Casimir force. We also calculate the Casimir force between two slabs of the forementioned materials with finite thicknesses to indicate the substrate's role in increasing the obtained Casimir force. Our simple calculation is interesting since one can extend it along with the Rigorous Coupled Wave Analysis to systems containing inhomogeneous layers as good candidates for designing nanomechanical devices.

  2. Intensifying the Casimir force between two silicon substrates within three different layers of materials

    Energy Technology Data Exchange (ETDEWEB)

    Seyedzahedi, A. [Department of Science, University of Kurdistan, Sanandaj (Iran, Islamic Republic of); Moradian, A., E-mail: a.moradian@uok.ac.ir [Department of Science, Campus of Bijar, University of Kurdistan, Bijar (Iran, Islamic Republic of); Setare, M.R., E-mail: rezakord@ipm.ir [Department of Science, University of Kurdistan, Sanandaj (Iran, Islamic Republic of)

    2016-04-01

    We investigate the Casimir force for a system composed of two thick slabs as substrates within three different homogeneous layers. We use the scattering approach along with the Matsubara formalism in order to calculate the Casimir force at finite temperature. First, we focus on constructing the reflection matrices and then we calculate the Casimir force for a water–lipid system. According to the conventional use of silicon as a substrate, we apply the formalism to calculate the Casimir force for layers of Au, VO{sub 2}, mica, KCl and foam rubber on the thick slabs of silicon. Afterwards, introducing an increasing factor, we compare our results with Lifshitz force in the vacuum between two semispaces of silicon in order to illustrate the influence of the layers on intensifying the Casimir force. We also calculate the Casimir force between two slabs of the forementioned materials with finite thicknesses to indicate the substrate's role in increasing the obtained Casimir force. Our simple calculation is interesting since one can extend it along with the Rigorous Coupled Wave Analysis to systems containing inhomogeneous layers as good candidates for designing nanomechanical devices.

  3. Study on isothermal precision forging process of rare earth intensifying magnesium alloy

    International Nuclear Information System (INIS)

    Shan, Debin; Xu, Wenchen; Han, Xiuzhu; Huang, Xiaolei

    2012-01-01

    A three dimensional rigid-plastic finite element model is established to simulate the isothermal precision forging process of the magnesium alloy bracket based on DEFORM 3D in order to analyze the material flow rule and determine the forging process scheme. Some problems such as underfilling and too large forging pressure are predicted and resolved through optimizing the shapes of the billet successfully. Compared to the initial microstructure, the isothermal-forged microstructure of the alloy refines obviously and amounts of secondary phases precipitate on the matrix during isothermal forging process. In subsequent ageing process, large quantities of secondary phases precipitate from α-Mg matrix with increasing ageing time. The optimal comprehensive mechanical properties of the alloy have been obtained after aged at 473 K, 63 h with the ultimate tensile strength, tensile yield strength and elongation 380 MPa, 243 MPa and 4.07% respectively, which shows good potential for application of isothermal forging process of rare earth intensifying magnesium alloy.

  4. intensifying and reorienting transfer of low carbon technologies for climate change prevention

    International Nuclear Information System (INIS)

    Pisani-Ferry, Jean; Monange, Herve; Gorges, Delphine; Senne, Valerie; Roulle, Jean-Michel

    2013-10-01

    The transfer of 'low carbon' technologies is crucial in order to moderate greenhouse gas (GHG) emissions by developing countries, which are set to rise significantly. Their implementation will determine the success of a global agreement on climate change in 2015, and this is the task of the Technology Mechanism, created in 2010. This policy brief sets out the principal results of a study commissioned from the Mines ParisTech Industrial Economics Centre (CERNA). The study shows that, unlike China, Mexico, South Africa and, to a lesser extent, Brazil, India is currently left out of international flows of low carbon technologies transfer - it is therefore a top priority, as is the rest of developing Asia, Africa and Eastern Europe. To intensify these transfers, ambitious greenhouse gas emissions reduction policies need to be implemented and absorptive capacities need to be created in countries that receive such technologies. In emerging countries, which possess a genuine capacity for innovation, and which are involved in international trade, the strengthening of intellectual property rights and the lowering of barriers to trade and investment are to be recommended. However, in the least developed countries, emphasis must be placed on technology absorptive capacities and in particular on the development of a qualified labour force

  5. Root growth of tomato seedlings intensified by humic substances from peat bogs

    Directory of Open Access Journals (Sweden)

    Alexandre Christofaro Silva

    2011-10-01

    Full Text Available Peats are an important reserve of humified carbon in terrestrial ecosystems. The interest in the use of humic substances as plant growth promoters is continuously increasing. The objective of this study was to evaluate the bioactivity of alkaline soluble humic substances (HS, humic (HA and fulvic acids (FA isolated from peats with different decomposition stages of organic matter (sapric, fibric and hemic in the Serra do Espinhaço Meridional, state of Minas Gerais. Dose-response curves were established for the number of lateral roots growing from the main plant axis of tomato seedlings. The bioactivity of HA was greatest (highest response in lateral roots at lowest concentration while FA did not intensify root growth. Both HS and HA stimulated root hair formation. At low concentrations, HS and HA induced root hair formation near the root cap, a typical hormonal imbalance effect in plants. Transgenic tomato with reporter gene DR5::GUS allowed the observation that the auxin-related signalling pathway was involved in root growth promotion by HA.

  6. Paediatric interventional cardiology: flat detector versus image intensifier using a test object

    Science.gov (United States)

    Vano, E.; Ubeda, C.; Martinez, L. C.; Leyton, F.; Miranda, P.

    2010-12-01

    Entrance surface air kerma (ESAK) values and image quality parameters were measured and compared for two biplane angiography x-ray systems dedicated to paediatric interventional cardiology, one equipped with image intensifiers (II) and the other one with dynamic flat detectors (FDs). Polymethyl methacrylate phantoms of different thicknesses, ranging from 8 to 16 cm, and a Leeds TOR 18-FG test object were used. The parameters of the image quality evaluated were noise, signal-difference-to-noise ratio (SdNR), high contrast spatial resolution (HCSR) and three figures of merit combining entrance doses and signal-to-noise ratios or HCSR. The comparisons showed a better behaviour of the II-based system in the low contrast region over the whole interval of thicknesses. The FD-based system showed a better performance in HCSR. The FD system evaluated would need around two times more dose than the II system evaluated to reach a given value of SdNR; moreover, a better spatial resolution was measured (and perceived in conventional monitors) for the system equipped with flat detectors. According to the results of this paper, the use of dynamic FD systems does not lead to an automatic reduction in ESAK or to an automatic improvement in image quality by comparison with II systems. Any improvement also depends on the setting of the x-ray systems and it should still be possible to refine these settings for some of the dynamic FDs used in paediatric cardiology.

  7. Using a Non-Fit Message Helps to De-Intensify Negative Reactions to Tough Advice

    Science.gov (United States)

    Fridman, Ilona; Scherr, Karen; Glare, Paul; Higgins, E. Tory

    2017-01-01

    Sometimes physicians need to provide patients with potentially upsetting advice. For example, physicians may recommend hospice for a terminally ill patient because it best meets their needs, but the patient and their family dislike this advised option. We explore whether regulatory non-fit could be used to improve these types of situations. Across five studies in which participants imagined receiving upsetting advice from a physician, we demonstrate that regulatory non-fit between the form of the physician’s advice (emphasizing gains vs. avoiding losses) and the participants’ motivational orientation (promotion vs. prevention) improves participants’ evaluation of an initially disliked option. Regulatory non-fit de-intensifies participants’ initial attitudes by making them less confident in their initial judgments and motivating them to think more thoroughly about the arguments presented. Furthermore, consistent with previous research on regulatory fit, we showed that the mechanism of regulatory non-fit differs as a function of participants’ cognitive involvement in the evaluation of the option. PMID:27341845

  8. Real-Time Detection of Sporadic Meteors in the Intensified TV Imaging Systems.

    Science.gov (United States)

    Vítek, Stanislav; Nasyrova, Maria

    2017-12-29

    The automatic observation of the night sky through wide-angle video systems with the aim of detecting meteor and fireballs is currently among routine astronomical observations. The observation is usually done in multi-station or network mode, so it is possible to estimate the direction and the speed of the body flight. The high velocity of the meteorite flying through the atmosphere determines the important features of the camera systems, namely the high frame rate. Thanks to high frame rates, such imaging systems produce a large amount of data, of which only a small fragment has scientific potential. This paper focuses on methods for the real-time detection of fast moving objects in the video sequences recorded by intensified TV systems with frame rates of about 60 frames per second. The goal of our effort is to remove all unnecessary data during the daytime and make free hard-drive capacity for the next observation. The processing of data from the MAIA (Meteor Automatic Imager and Analyzer) system is demonstrated in the paper.

  9. Can we Observe and Assess Whether the Global Hydrological Cycle is "Intensifying"?

    Science.gov (United States)

    Wood, E. F.; Sheffield, J.

    2012-12-01

    There is controversy over whether the hydrological cycle is "intensifying" (or "accelerating"), and if so how and where? Resolving this critical question is a central goal of both national (e.g. NASA's Energy and Water cycle Study: NEWS) and international (WCRP Global Energy and Water cycle Experiment: GEWEX) programs. Its resolution has significant implications for understanding changes in hydroclimatic states and variability, and in future water security at regional to global scales. Over the last decade a number of papers have addressed trends and change in specific water cycle variables with results that can best be described as inconclusive, regardless of the conclusions of specific papers. In this presentation a number of recent studies will be reviewed for their consistency in assessing whether collectively one can make conclusions regarding how the hydrologic cycle is changing. The presentation will also demonstrate a pathway for analyzing where to observe for the detection of change based on a NASA-supported, global, 1983-2009, terrestrial water cycle Earth System Data Record project being led by the author. Initial results will be presented and a discussion presented on the extent that the proposed strategy can be used to detect change in the terrestrial hydrological cycle.

  10. Dynamic flat panel detector versus image intensifier in cardiac imaging: dose and image quality

    Science.gov (United States)

    Vano, E.; Geiger, B.; Schreiner, A.; Back, C.; Beissel, J.

    2005-12-01

    The practical aspects of the dosimetric and imaging performance of a digital x-ray system for cardiology procedures were evaluated. The system was configured with an image intensifier (II) and later upgraded to a dynamic flat panel detector (FD). Entrance surface air kerma (ESAK) to phantoms of 16, 20, 24 and 28 cm of polymethyl methacrylate (PMMA) and the image quality of a test object were measured. Images were evaluated directly on the monitor and with numerical methods (noise and signal-to-noise ratio). Information contained in the DICOM header for dosimetry audit purposes was also tested. ESAK values per frame (or kerma rate) for the most commonly used cine and fluoroscopy modes for different PMMA thicknesses and for field sizes of 17 and 23 cm for II, and 20 and 25 cm for FD, produced similar results in the evaluated system with both technologies, ranging between 19 and 589 µGy/frame (cine) and 5 and 95 mGy min-1 (fluoroscopy). Image quality for these dose settings was better for the FD version. The 'study dosimetric report' is comprehensive, and its numerical content is sufficiently accurate. There is potential in the future to set those systems with dynamic FD to lower doses than are possible in the current II versions, especially for digital cine runs, or to benefit from improved image quality.

  11. BaFCl:Eu2+, a new phosphor for X-ray-intensifying screens

    International Nuclear Information System (INIS)

    Stevels, A.L.N.; Pingault, F.

    1975-01-01

    A number of phosphors for X-ray-intensifying screens have been evaluated by calculating figures of merit. On use in combination with standard (''blue''-sensitive) X-ray film, BaFCl:Eu 2+ and BaFBr:Eu 2+ give better performance than the traditional CaWO 4 and more recently developed UV or blue-emitting materials (e.g., sulphates and y-oxysulphides). The calculated figures of merit of BaFCl:Eu 2+ or BaFBr:Eu 2+ /standard-film combinations are comparable to those of Gd 2 O 2 S:Tb/green-sensitive X-ray film systems. The preparation of optimal fluorohalide:Eu 2+ phosphors involves proper formation of the host lattice, complete reduction of Eu 3+ ions as well as elimination of afterglow. Measurements on powders and experimental screens indicate that by using BaFCl:Eu 2+ screens in radiography, important dose reductions can be achieved without the necessity of using other than standard (''blue''-sensitive) X-ray films

  12. Sensitometry of intensifying screen-film system for detection of yearly change of imaging quality factors

    International Nuclear Information System (INIS)

    Yoshida, Akira; Asahara, Masayoshi

    2002-01-01

    Systematic sensitometry of 20 green- and 25 blue-intensifying screens made in early 1980s and early 1990s was performed on their physical imaging qualities to evaluate their yearly change. Sensitometry was done with Toshiba KXO-1000 X-ray generator (Tube: Toshiba DRX-431HD, 80 kV, 20 mm-thick Al-filter), characteristic curve examination with KXO-15 (Tube: DRX-1603B, 80 kV, 0.5 mm Cu+4.0 mm Al), determination of modulation transfer function with KXO-15 (Tube: DRX-1303B, 80 kV, 2.0 mm Al), and Wiener spectrometry with Hitachi DH-158 (Tube: Hitachi UH-6GC-108DL, 80 kV, 20 mmAl). Reference screen was that reported by US Bureau of Radiological Health (1982) and Center for Devices and Radiological Health (196) and was obtained from Chicago University. There were products without yearly change, with increased sensitivity with unchanged resolution and noise level, with improved resolution, or with improved sensitivity. (K.H.)

  13. Intensified summer monsoon and the urbanization of Indus Civilization in northwest India.

    Science.gov (United States)

    Dixit, Yama; Hodell, David A; Giesche, Alena; Tandon, Sampat K; Gázquez, Fernando; Saini, Hari S; Skinner, Luke C; Mujtaba, Syed A I; Pawar, Vikas; Singh, Ravindra N; Petrie, Cameron A

    2018-03-09

    Today the desert margins of northwest India are dry and unable to support large populations, but were densely occupied by the populations of the Indus Civilization during the middle to late Holocene. The hydroclimatic conditions under which Indus urbanization took place, which was marked by a period of expanded settlement into the Thar Desert margins, remains poorly understood. We measured the isotopic values (δ 18 O and δD) of gypsum hydration water in paleolake Karsandi sediments in northern Rajasthan to infer past changes in lake hydrology, which is sensitive to changing amounts of precipitation and evaporation. Our record reveals that relatively wet conditions prevailed at the northern edge of Rajasthan from ~5.1 ± 0.2 ka BP, during the beginning of the agricultural-based Early Harappan phase of the Indus Civilization. Monsoon rainfall intensified further between 5.0 and 4.4 ka BP, during the period when Indus urban centres developed in the western Thar Desert margin and on the plains of Haryana to its north. Drier conditions set in sometime after 4.4 ka BP, and by ~3.9 ka BP an eastward shift of populations had occurred. Our findings provide evidence that climate change was associated with both the expansion and contraction of Indus urbanism along the desert margin in northwest India.

  14. Paediatric interventional cardiology: flat detector versus image intensifier using a test object

    Energy Technology Data Exchange (ETDEWEB)

    Vano, E [Radiology Department, Medicine School, Complutense University and San Carlos University Hospital, 28040 Madrid (Spain); Ubeda, C [Clinical Sciences Department, Faculty of the Science of Health and CIHDE, Tarapaca University, 18 de Septiembre 2222, Arica (Chile); Martinez, L C [Medical Physics and Radiation Protection Service, 12 de Octubre University Hospital, Madrid (Spain); Leyton, F [Institute of Public Health of Chile, Marathon 1000, Nunoa, Santiago (Chile); Miranda, P, E-mail: eliseov@med.ucm.e [Hemodynamic Department, Cardiovascular Service, Luis Calvo Mackenna Hospital, Avenida Antonio Varaas 360, Providencia, Santiago (Chile)

    2010-12-07

    Entrance surface air kerma (ESAK) values and image quality parameters were measured and compared for two biplane angiography x-ray systems dedicated to paediatric interventional cardiology, one equipped with image intensifiers (II) and the other one with dynamic flat detectors (FDs). Polymethyl methacrylate phantoms of different thicknesses, ranging from 8 to 16 cm, and a Leeds TOR 18-FG test object were used. The parameters of the image quality evaluated were noise, signal-difference-to-noise ratio (SdNR), high contrast spatial resolution (HCSR) and three figures of merit combining entrance doses and signal-to-noise ratios or HCSR. The comparisons showed a better behaviour of the II-based system in the low contrast region over the whole interval of thicknesses. The FD-based system showed a better performance in HCSR. The FD system evaluated would need around two times more dose than the II system evaluated to reach a given value of SdNR; moreover, a better spatial resolution was measured (and perceived in conventional monitors) for the system equipped with flat detectors. According to the results of this paper, the use of dynamic FD systems does not lead to an automatic reduction in ESAK or to an automatic improvement in image quality by comparison with II systems. Any improvement also depends on the setting of the x-ray systems and it should still be possible to refine these settings for some of the dynamic FDs used in paediatric cardiology.

  15. Comparison of dose and image quality of a Flat-panel detector and an image intensifier

    International Nuclear Information System (INIS)

    Lazzaro, M.; Friedrich, B.Q.; Luz, R.M. da; Silva, A.M.M. da

    2016-01-01

    With the development of new technologies, have emerged new conversion methods of X-ray image, such as flat panel detectors. The aim of this work is the comparison of entrance surface air kerma (ESAK) and image quality between an image intensifier type of detector (A) and a flat panel (B). The ESAK was obtained by placing a ionization chamber under PMMA simulators of 10, 20 and 30 cm and the image quality was obtained by using the TOR "1"8FG simulator. The ESAK to the equipment A is higher when compared to the equipment B. The high contrast resolution is better for the equipment A for all thicknesses of simulators. The equipment A has low contrast resolution with a better viewing threshold for thicknesses of 10 and 20 cm, and a worse performance for 30 cm. It is concluded that the equipment B has ESAK smaller and despite having lower resolution, in almost all cases, have appropriate image quality for diagnosis. (author)

  16. Star tracking method based on multiexposure imaging for intensified star trackers.

    Science.gov (United States)

    Yu, Wenbo; Jiang, Jie; Zhang, Guangjun

    2017-07-20

    The requirements for the dynamic performance of star trackers are rapidly increasing with the development of space exploration technologies. However, insufficient knowledge of the angular acceleration has largely decreased the performance of the existing star tracking methods, and star trackers may even fail to track under highly dynamic conditions. This study proposes a star tracking method based on multiexposure imaging for intensified star trackers. The accurate estimation model of the complete motion parameters, including the angular velocity and angular acceleration, is established according to the working characteristic of multiexposure imaging. The estimation of the complete motion parameters is utilized to generate the predictive star image accurately. Therefore, the correct matching and tracking between stars in the real and predictive star images can be reliably accomplished under highly dynamic conditions. Simulations with specific dynamic conditions are conducted to verify the feasibility and effectiveness of the proposed method. Experiments with real starry night sky observation are also conducted for further verification. Simulations and experiments demonstrate that the proposed method is effective and shows excellent performance under highly dynamic conditions.

  17. Climate change and ocean deoxygenation within intensified surface-driven upwelling circulations.

    Science.gov (United States)

    Bakun, Andrew

    2017-09-13

    Ocean deoxygenation often takes place in proximity to zones of intense upwelling. Associated concerns about amplified ocean deoxygenation arise from an arguable likelihood that coastal upwelling systems in the world's oceans may further intensify as anthropogenic climate change proceeds. Comparative examples discussed include the uniquely intense seasonal Somali Current upwelling, the massive upwelling that occurs quasi-continuously off Namibia and the recently appearing and now annually recurring 'dead zone' off the US State of Oregon. The evident 'transience' in causal dynamics off Oregon is somewhat mirrored in an interannual-scale intermittence in eruptions of anaerobically formed noxious gases off Namibia. A mechanistic scheme draws the three examples towards a common context in which, in addition to the obvious but politically problematic remedy of actually reducing 'greenhouse' gas emissions, the potentially manageable abundance of strongly swimming, finely gill raker-meshed small pelagic fish emerges as a plausible regulating factor.This article is part of the themed issue 'Ocean ventilation and deoxygenation in a warming world'. © 2017 The Author(s).

  18. Multiscale hydrodynamic investigation to intensify the biogas production in upflow anaerobic reactors.

    Science.gov (United States)

    Jiang, Jiankai; Wu, Jing; Zhang, Jinbai; Poncin, Souhila; Li, Huai Z

    2014-03-01

    Hydrodynamics plays a main role for the performance of an anaerobic reactor involving three phases: wastewater, sludge granules and biogas bubbles. The present work was focused on an original approach to investigate the hydrodynamics at different scales and then to intensify the performance of such complex reactors. The experiments were carried out respectively in a 3D reactor at macroscale, a 2D reactor at mesoscale and a 1D anaerobic reactor at microscale. A Particle Image Velocimetry (PIV), a micro-PIV and a high-speed camera were employed to quantify the liquid flow fields and the relative motion between sludge granules and bubbles. Shear rates exerted on sludge granules were quantified from liquid flow fields. The optimal biogas production is obtained at mean shear rate varying from 28 to 48s(-1), which is controlled by two antagonistic mechanisms. The multiscale approach demonstrates pertinent mechanisms proper to each scale and allows a better understanding of such reactors. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. Intuitive Choices Lead to Intensified Positive Emotions: An Overlooked Reason for "Intuition Bias"?

    Science.gov (United States)

    Kirkebøen, Geir; Nordbye, Gro H H

    2017-01-01

    People have, for many well-documented reasons, a tendency to overemphasize their intuitions and to follow them, even when they should not. This "intuition bias" leads to several kinds of specific intuitive biases in judgments and decision making. Previous studies have shown that characteristics of the decision process have a tendency to "leak" into the experience of the choice outcome. We explore whether intuitive choices influence the experience of the choice outcomes differently from "non-intuitive," analytic choices. Since intuition is feeling based, we examine in particular if intuitive choices have stronger affective consequences than non-intuitive ones. Participants in two scenario studies ( N = 90; N = 126) rated the feelings of decision makers who experienced a conflict between two options, one intuitively appealing and another that appeared preferable on analytic grounds. Choosing the intuitive alternative was anticipated to lead to somewhat more regret after negative outcomes and, in particular, much more satisfaction with positive outcomes. In two autobiographical studies, one with psychology students ( N = 88) and the other with experienced engineers ( N = 99), participants were asked to provide examples of choice conflicts between an intuitive and a non-intuitive option from their own private or professional lives. Both groups showed a tendency to report stronger emotions, in particular positive, after intuitive choices. One well-established explanation for intuition bias focuses on the nature of people's anticipated negative counterfactual thoughts if their decisions were to turn out badly. The present data indicate that intuitive choices intensify positive emotions, anticipated and real, after successful outcomes much more than negative emotions after failures. Positive outcomes are also more commonly expected than negative ones, when we make choices. We argue that markedly amplified emotions, mediated by stronger personal involvement, in the

  20. Intensified association between waist circumference and hypertension in abdominally overweight children.

    Science.gov (United States)

    Dong, Bin; Wang, Zhiqiang; Yang, Yide; Wang, Hai-Jun; Ma, Jun

    2016-01-01

    Abdominal adiposity is an important risk factor for childhood hypertension. The present study aimed to compare the strength of the association between waist circumference (WC) and hypertension in children with different WC levels. A total of 82,413 Chinese children aged 9-17 years were selected. An abdominally overweight child was defined as a child with WC ≥75th sex- and age-specific percentile. Hypertension was categorised as ≥95th sex-, age- and height-specific percentile. Logistic regression model was applied to calculate the odds ratio (OR) and 95% confidence interval (CI) of WC for hypertension after WC was transformed into sex- and age-specific z-score. Abdominally overweight children presented a higher risk of hypertension (OR: 2.39; 95% CI: 2.26, 2.54) than children with normal WC. In children with normal WC, one sex- and age-specific standard deviation increase in WC was associated with a 42% increase in odds of hypertension (OR: 1.42; 95% CI: 1.30, 1.55). That increase was elevated to 74% in abdominally overweight children (OR: 1.74; 95% CI: 1.66, 1.82). A similar pattern was also observed in different sex and area groups, and in children 9-14 years old. An intensified association between WC and hypertension was observed in abdominally overweight Chinese children. The gain in WC was associated with greater increase in hypertensive risk in abdominally overweight children than that of children with normal WC. These findings could improve intervention strategies for hypertension risk reduction in children. Copyright © 2015 Asia Oceania Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.

  1. Neutron diffraction tomography: a unique, 3D inspection technique for crystals using an intensifier TV system

    International Nuclear Information System (INIS)

    Davidson, J.B.; Case, A.L.

    1978-01-01

    The application of phosphor-intensifier-TV techniques to neutron topography and tomography of crystals is described. The older, analogous x-ray topography using wavelengths approximately 1.5A is widely used for surface inspection. However, the crystal must actually be cut in order to see diffraction anomalies beneath the surface. Because 1.5-A thermal neutrons are highly penetrating, much larger and thicker specimens can be used. Also, since neutrons have magnetic moments, they are diffracted by magnetic structures within crystals. In neutron volume topography, the entire crystal or a large part of it is irradiated, and the images obtained are superimposed reflections from the total volume. In neutron tomography (or section topography), a collimated beam irradiates a slice (0.5 to 10 mm) of the crystal. The diffracted image is a tomogram from this part only. A series of tomograms covering the crystal can be taken as the specimen is translated in steps across the narrow beam. Grains, voids, twinning, and other defects from regions down to 1 mm in size can be observed and isolated. Although at present poorer in resolution than the original neutron and film methods, the TV techniques are much faster and, in some cases, permit real-time viewing. Two camera systems are described: a counting camera having a 150 mm 6 Li-ZnS screen for low-intensity reflections which are integrated in a digital memory, and a 300-mm system using analog image storage. Topographs and tomograms of several crystals ranging in size from 4 mm to 80 mm are shown

  2. Application of an image intensifier to the study on hadrons in air shower, 4

    International Nuclear Information System (INIS)

    Tsushima, Itsuro; Kawasumi, Norio; Hashimoto, Katsumi; Machida, Masaharu

    1975-01-01

    As the apparatus for observing cosmic ray air shower, the particle detection apparatus combining spark chamber, scintillator and photomultiplier tube is frequently used, but the exact detection of particle number is impossible with it when particle density is large. The authors have carried out the experiment to measure nuclear active particles in air shower and to grasp the central part of air shower as energy flow by utilizing an image intensifier tube. On the roof of building S, a laboratory was built, and a core detector of 2 m x 2 m area, 13 AS detectors of 0.25 m 2 and an AS detector of 1 m 2 were installed. The gate of the II was opened by utilizing coincidence pulses, and the position and amount of scintillation in the core detector was taken into a camera through the II. The time of observation was 289 hours, and the time of II operation was 113 hours. Total number of air shower recorded was 218 cases, and the centers of 120 cases among them were determined in the AS detectors at four corners. The centers of 39 cases were within the area of the core detector. In the coincident counting of air shower and burst carried out in the present experiment, the total delay time from the arrival of air shower to the gate pulse actuating the II was 1.6 sec. The core of air shower of about 10 6 size and 1.3 age was caught by this method. The problems for future are the determination of core position for the air shower of smaller size, and the meaning of spot images of II. (Kako, I.)

  3. Savings from controlled measurement operations during the selection of the methods of intensifying inflows

    Energy Technology Data Exchange (ETDEWEB)

    Pluden, I A

    1979-01-01

    Investigation was made of the effectiveness of the information preservation of problems on the selection of the methods of the intensification of the extraction of petroleum. On the basis of the methodology on the determination of the operational outlay for each well and the cost of the extraction of petroleum which was worked out by the All-Union Science Research Institute for Gas, the formulae concerning the dependence of the cost on the output of the wells is generalized for the case of flooded wells. Formulae are presented, which are suitable for the calculation of the savings on the application of the methods of intensifying extraction. The output of the wells is examined as a random value. Formulae are deduced for the density of the reliability and the function of the distribution of the cost of the extraction of petroleum per well, and a graph of this function of determination is given. The necessity of taking into consideration the error of the dimensions of measurements of the output of the wells in the calculations is pointed out. This error leads in practice to significant errors in the selection of intensification methods and the evaluation of its effectiveness, which in the last analysis has a significant economic disadvantage. Recommendations are made for showing the elimination of this disadvantage by rational organization of the measurement control operations. A graph is made for the dependence between the duration of the measurements of the outputs of the wells and their frequency per month (periodicity) with various outputs of wells for the case when the error of the measurements of the yields does not exceed /sub +//sub -/5%.

  4. Enzymatically modified isoquercitrin supplementation intensifies plantaris muscle fiber hypertrophy in functionally overloaded mice.

    Science.gov (United States)

    Kohara, Akiko; Machida, Masanao; Setoguchi, Yuko; Ito, Ryouichi; Sugitani, Masanori; Maruki-Uchida, Hiroko; Inagaki, Hiroyuki; Ito, Tatsuhiko; Omi, Naomi; Takemasa, Tohru

    2017-01-01

    Enzymatically modified isoquercitrin (EMIQ) is produced from rutin using enzymatic hydrolysis followed by treatment with glycosyltransferase in the presence of dextrin to add glucose residues. EMIQ is absorbed in the same way as quercetin, a powerful antioxidant reported to prevent disused muscle atrophy by targeting mitochondria and to have ergogenic effects. The present study investigated the effect of EMIQ on skeletal muscle hypertrophy induced by functional overload. In Study 1, 6-week-old ICR male mice were divided into 4 groups: sham-operated control, sham-operated EMIQ, overload-operated control, and overload-operated EMIQ groups. In Study 2, mice were divided into 3 groups: overload-operated whey control, overload-operated whey/EMIQ (low dose), and overload-operated whey/EMIQ (high dose) groups. The functional overload of the plantaris muscle was induced by ablation of the synergist (gastrocnemius and soleus) muscles. EMIQ and whey protein were administered with food. Three weeks after the operation, the cross-sectional area and minimal fiber diameter of the plantaris muscle fibers were measured. In Study 1, functional overload increased the cross-sectional area and minimal fiber diameter of the plantaris muscle. EMIQ supplementation significantly increased the cross-sectional area and minimal fiber diameter of the plantaris muscle in both the sham-operated and overload-operated groups. In Study 2, EMIQ supplementation combined with whey protein administration significantly increased the cross-sectional area and minimal fiber diameter of the plantaris muscle. EMIQ, even when administered as an addition to whey protein supplementation, significantly intensified the fiber hypertrophy of the plantaris muscle in functionally overloaded mice. EMIQ supplementation also induced fiber hypertrophy of the plantaris in sham-operated mice.

  5. Application of intensified heat transfer for the retrofit of heat exchanger network

    International Nuclear Information System (INIS)

    Wang, Yufei; Pan, Ming; Bulatov, Igor; Smith, Robin; Kim, Jin-Kuk

    2012-01-01

    Highlights: → Novel design approach for the retrofit of HEN based on intensified heat transfer. → Development of a mathematical model to evaluate shell-and-tube heat exchanger performances. → Identification of the most appropriate heat exchangers requiring heat transfer enhancements in the heat exchanger network. -- Abstract: A number of design methods have been proposed for the retrofit of heat exchanger networks (HEN) during the last three decades. Although considerable potential for energy savings can be identified from conventional retrofit approaches, the proposed solutions have rarely been adopted in practice, due to significant topology modifications required and resulting engineering complexities during implementation. The intensification of heat transfer for conventional shell-and-tube heat exchangers can eliminate the difficulties of implementing retrofit in HEN which are commonly restricted by topology, safety and maintenance constraints, and includes high capital costs for replacing equipment and pipelines. This paper presents a novel design approach to solve HEN retrofit problems based on heat transfer enhancement. A mathematical model has been developed to evaluate shell-and-tube heat exchanger performances, with which heat-transfer coefficients and pressure drops for both fluids in tube and shell sides are obtained. The developed models have been compared with the Bell-Delaware, simplified Tinker and Wills-Johnston methods and tested with the HTRI (registered) and HEXTRAN (registered) software packages. This demonstrates that the new model is much simpler but can give reliable results in most cases. For the debottlenecking of HEN, four heuristic rules are proposed to identify the most appropriate heat exchangers requiring heat transfer enhancements in the HEN. The application of this new design approach allows a significant improvement in energy recovery without fundamental structural modifications to the network.

  6. Recent intensified impact of December Arctic Oscillation on subsequent January temperature in Eurasia and North Africa

    Science.gov (United States)

    He, Shengping; Wang, Huijun; Gao, Yongqi; Li, Fei

    2018-03-01

    This study reveals an intensified influence of December Arctic Oscillation (AO) on the subsequent January surface air temperature (SAT) over Eurasia and North Africa in recent decades. The connection is statistically insignificant during 1957/58-1979/80 (P1), which becomes statistically significant during 1989/90-2011/12 (P2). The possible causes are further investigated. Associated with positive December AO during P2, significant anomalous anticyclone emerges over the central North Atlantic, which is accompanied with significant westerly and easterly anomalies along 45°-65°N and 20°-40°N, respectively. This favors the significant influence of December AO on the subsequent January SAT and atmospheric circulation over Eurasia and North Africa via triggering the North Atlantic tripole sea surface temperature (SST) anomaly that persists into the subsequent January. By contrast, the December AO-related anomalous anticyclone during P1 is weak and is characterized by two separate centers located in the eastern and western North Atlantic. Correspondingly, the westerly and easterly anomalies over the North Atlantic Ocean are weak and the-related tripole SST anomaly is not well formed, unfavorable for the persistent impact of the December AO into the subsequent January. Further analyses indicate that the different anomalous anticyclone associated with the December AO over the North Atlantic may be induced by the strengthened synoptic-scale eddy feedbacks over the North Atlantic, which may be related to the interdecadal intensification of the storm track activity. Additionally, the planetary stationary wave related to the December AO propagates from surface into upper stratosphere at mid-latitudes during P2, which further propagates downward to the troposphere and causes anomalous atmospheric circulation in the subsequent January.

  7. Exogenous Acrolein intensifies sensory hypersensitivity after spinal cord injury in rat.

    Science.gov (United States)

    Butler, Breanne; Acosta, Glen; Shi, Riyi

    2017-08-15

    Acrolein, an α,β-unsaturated aldehyde associated with oxidative stress, is also a major toxic component of tobacco cigarette smoke, which has been reported in the clinic to coincide with the exacerbation of neuropathic pain after SCI. Previous reports have shown that acrolein involvement in spinal cord injury (SCI) is crucial to the development and persistence of neuropathic pain. Through the activation and upregulation of the transient receptor protein ankyrin-1 (TRPA1) cation channel, acrolein is capable of sensitizing the central nervous system in the acute and chronic stages of SCI. Here, we report that the acute or delayed nasal exposure of acrolein, apart from cigarette smoke but at concentrations similar to that found in cigarette smoke, resulted in increased neuropathic pain behaviors in a rat model of contusion SCI. We also found that this hyperalgesia occurred concurrently with an augmentation in systemic acrolein, detected by an acrolein-glutathione metabolite in the urine. The application of an acrolein scavenger, phenelzine, was shown to reduce the hyperalgesic effect of acrolein inhalation. The previously determined ability of acrolein to bind to and activate the TRPA1 channel and elicit algesic responses may be a mechanism of the phenomenon seen in this study. Upon the exposure to actual cigarette smoke after SCI, intensified neuropathic pain behaviors were also observed and persisted for at least 1week after the cessation of the exposure period. Taken together, these results indicate that cigarette smoke, through mechanisms involving acrolein, poses a threat to the vulnerable CNS after SCI and can contribute to neuropathic pain. This investigation also provides further evidence for the potential utility of acrolein scavengers as a therapeutic strategy in SCI-resultant neuropathic pain. Copyright © 2017. Published by Elsevier B.V.

  8. Continuous, but not intermittent, antipsychotic drug delivery intensifies the pursuit of reward cues.

    Science.gov (United States)

    Bédard, Anne-Marie; Maheux, Jérôme; Lévesque, Daniel; Samaha, Anne-Noël

    2011-05-01

    Chronic exposure to antipsychotic medications can persistently change brain dopamine systems. Most studies on the functional significance of these neural changes have focused on motor behavior and few have addressed how long-term antipsychotic treatment might influence dopamine-mediated reward function. We asked, therefore, whether a clinically relevant antipsychotic treatment regimen would alter the incentive motivational properties of a reward cue. We assessed the ability of a Pavlovian-conditioned stimulus to function as a conditioned reward, as well as to elicit approach behavior in rats treated with haloperidol, either continuously (achieved via subcutaneous osmotic minipump) or intermittently (achieved via daily subcutaneous injections). Continuous, but not intermittent, treatment enhanced the ability of amphetamine to potentiate the conditioned reinforcing effects of a cue associated with water. This effect was not related to differences in the ability to attribute predictive value to a conditioned stimulus (as measured by conditioned approach behavior), but was potentially linked to the development of behavioral supersensitivity to amphetamine and to augmented amphetamine-induced immediate early-gene expression (c-fos and Nur77) in dorsal striatopallidal and striatonigral cells. By enhancing the ability of reward cues to control behavior and by intensifying dopamine-mediated striatopallidal and striatonigral cell activity, standard (ie, continuous) antipsychotic treatment regimens might exacerbate drug-seeking and drug-taking behavior in schizophrenia. Achieving regular but transiently high antipsychotic levels in the brain (as modeled in the intermittent condition) might be a viable option to prevent these changes. This possibility should be explored in the clinic.

  9. Maternal high-fat diet intensifies the metabolic response to stress in male rat offspring.

    Science.gov (United States)

    Karbaschi, Roxana; Zardooz, Homeira; Khodagholi, Fariba; Dargahi, Leila; Salimi, Mina; Rashidi, FatemehSadat

    2017-01-01

    The mother's consumption of high-fat food can affect glucose metabolism and the hypothalamic-pituitary-adrenal axis responsiveness in the offspring and potentially affect the metabolic responses to stress as well. This study examines the effect of maternal high-fat diet on the expression of pancreatic glucose transporter 2 and the secretion of insulin in response to stress in offspring. Female rats were randomly divided into normal and high-fat diet groups and were fed in accordance with their given diets from pre-pregnancy to the end of lactation. The offspring were divided into control (NC and HFC) and stress (NS and HFS) groups based on their mothers' diet and exposure to stress in adulthood. After the two-week stress induction period was over, an intraperitoneal glucose tolerance test (IPGTT) was performed and plasma glucose and insulin levels were assessed. The pancreas was then removed for measuring insulin secretion from the isolated islets as well as glucose transporter 2 mRNA expression and protein levels. According to the results obtained, plasma corticosterone concentrations increased significantly on days 1 and 14 of the stress induction period and were lower on the last day compared to on the first day. In both the NS and HFS groups, stress reduced plasma insulin concentration in the IPGTT without changing the plasma glucose concentration, suggesting an increased insulin sensitivity in the NS and HFS groups, although more markedly in the latter. Stress reduced insulin secretion (at high glucose concentrations) and increased glucose transporter 2 mRNA and protein expression, especially in the HFS group. Mothers' high-fat diet appears to intensify the stress response by changing the programming of the neuroendocrine system in the offspring.

  10. Is climate change intensifying the drying-trend in the Caribbean?

    Science.gov (United States)

    Herrera, D. A.; Ault, T.; Fasullo, J.; Carrillo, C. M.

    2017-12-01

    Since 1950, the Caribbean (11ºN-25ºN; 85ºW-60ºW) has seen a significant drying trend characterized by several recent droughts, some of them contemporaneous with El Niño events. Moreover, the most recent drought from 2013 to 2016 was both the most severe and widespread event since at least 1950, and was associated with high temperatures, likely driven in part by climate change. This work examines the role of increased evaporative demand resulting from warmer temperatures on the drying trend observed in the Caribbean since 1950, using observations and model simulations. Large-scale dynamics associated with drought are also analyzed using sea surface temperature, geopotential height, wind, and precipitation anomalies, as well as radiative fluxes anomalies. Furthermore, land surface model soil moisture and high-resolution self-calibrated Palmer Drought Severity Index (scPDSI) datasets are used to quantify drought severity at local scales. The anthropogenic contribution to drought severity is estimated as the difference between the scPDSI calculated using linearly-detrended temperatures, and the scPDSI computed with the observed trend, with unadjusted precipitation, net radiation, and wind speed. Soil moisture anomalies driven by climate change are derived by comparing a large ensemble of forced simulations against a pre-industrial control. The resulting analysis indicates that anthropogenic forcing has intensified the drying trend in the Caribbean by -0.4 scPDSI-units over 60 years, and has increased the dry-land area by 10%. These findings are consistent with observed potential evapotranspiration (PET) anomalies, which are 30% higher than PET-anomalies estimated using detrended temperatures. These results suggest that climate change is already increasing the risk of drought in the Caribbean by enhancing the atmospheric demand of moisture through temperature, and provide insights into the role of climate change in future drought risk in the region.

  11. Measurement and monitoring of entrance exposure dose rate in X-ray image intensifier television with dose rate control

    Energy Technology Data Exchange (ETDEWEB)

    Klein, J [Bezirkskrankenhaus Brandenburg (German Democratic Republic)

    1981-03-01

    For X-ray image intensifier television operation very low entrance dose rates (about 5.2 nA/kg) are stated and demanded, respectively. These required values are often manifold exceeded in practice so that a check seems to be necessary. It is shown and proved how these measurements can be performed with simple, generally available means of measurement in the radiological practice. For ZnCdS-image intensifiers should be considered that about 13 nA/kg for the large entrance size are not to be exceeded; for the CsI type lower values (factor 1.5) are practicable because of the twofold quantum absorption efficiency. Furthermore, some tests for a semiquantitative function check of the automatic dose rate control are proposed.

  12. The effects of intensified training on resting metabolic rate (RMR), body composition and performance in trained cyclists

    Science.gov (United States)

    Lundy, Bronwen; Rogers, Margot A.; Welvaert, Marijke; Halson, Shona; McKune, Andrew

    2018-01-01

    Background Recent research has demonstrated decreases in resting metabolic rate (RMR), body composition and performance following a period of intensified training in elite athletes, however the underlying mechanisms of change remain unclear. Therefore, the aim of the present study was to investigate how an intensified training period, designed to elicit overreaching, affects RMR, body composition, and performance in trained endurance athletes, and to elucidate underlying mechanisms. Method Thirteen (n = 13) trained male cyclists completed a six-week training program consisting of a “Baseline” week (100% of regular training load), a “Build” week (~120% of Baseline load), two “Loading” weeks (~140, 150% of Baseline load, respectively) and two “Recovery” weeks (~80% of Baseline load). Training comprised of a combination of laboratory based interval sessions and on-road cycling. RMR, body composition, energy intake, appetite, heart rate variability (HRV), cycling performance, biochemical markers and mood responses were assessed at multiple time points throughout the six-week period. Data were analysed using a linear mixed modeling approach. Results The intensified training period elicited significant decreases in RMR (F(5,123.36) = 12.0947, p = HRV (F(2,22.608) = 6.5212, p = 0.005); all of which improved following a period of recovery. A state of overreaching was induced, as identified by a reduction in anaerobic performance (F(5,121.87) = 8.2622, p = HRV during intensified training periods may alleviate fatigue and attenuate the observed decrease in RMR, providing more optimal conditions for a positive training adaptation. PMID:29444097

  13. An Analysis of the Observed Low-level Structure of Rapidly Intensifying and Mature Hurricane Earl (2010)

    Science.gov (United States)

    2014-01-01

    structure. J. Atmos. Sci. 49: 919–942. Marks FD, Black PG, Montgomery MT, Burpee RW. 2008. Structure of the eye and eyewall of hurricane Hugo (1989...structure of rapidly intensifying and mature hurricane Earl (2010) Michael T. Montgomery,a* Jun A. Zhangb and Roger K. Smithc aDepartment of Meteorology...Naval Postgraduate School, Monterey, CA, USA bNOAA Hurricane Research Division, Miami, FL, USA cMeteorological Institute, Ludwig Maximilians, University

  14. C.C.D. readout of a picosecond streak camera with an intensified C.C.D

    International Nuclear Information System (INIS)

    Lemonier, M.; Richard, J.C.; Cavailler, C.; Mens, A.; Raze, G.

    1984-08-01

    This paper deals with a digital streak camera readout device. The device consists in a low light level television camera made of a solid state C.C.D. array coupled to an image intensifier associated to a video-digitizer coupled to a micro-computer system. The streak camera images are picked-up as a video signal, digitized and stored. This system allows the fast recording and the automatic processing of the data provided by the streak tube

  15. Dynamic imaging with a triggered and intensified CCD camera system in a high-intensity neutron beam

    International Nuclear Information System (INIS)

    Vontobel, P.; Frei, G.; Brunner, J.; Gildemeister, A.E.; Engelhardt, M.

    2005-01-01

    When time-dependent processes within metallic structures should be inspected and visualized, neutrons are well suited due to their high penetration through Al, Ag, Ti or even steel. Then it becomes possible to inspect the propagation, distribution and evaporation of organic liquids as lubricants, fuel or water. The principle set-up of a suited real-time system was implemented and tested at the radiography facility NEUTRA of PSI. The highest beam intensity there is 2x10 7 cm -2 s -1 , which enables to observe sequences in a reasonable time and quality. The heart of the detection system is the MCP intensified CCD camera PI-Max with a Peltier cooled chip (1300x1340 pixels). The intensifier was used for both gating and image enhancement, where as the information was accumulated over many single frames on the chip before readout. Although, a 16-bit dynamic range is advertised by the camera manufacturers, it must be less due to the inherent noise level from the intensifier. The obtained result should be seen as the starting point to go ahead to fit the different requirements of car producers in respect to fuel injection, lubricant distribution, mechanical stability and operation control. Similar inspections will be possible for all devices with repetitive operation principle. Here, we report about two measurements dealing with the lubricant distribution in a running motorcycle motor turning at 1200rpm. We were monitoring the periodic stationary movements of piston, valves and camshaft with a micro-channel plate intensified CCD camera system (PI-Max 1300RB, Princeton Instruments) triggered at exactly chosen time points

  16. Forecast simulation of rapidly-intensified typhoon in the Eddy-Rich Northwest Pacific region

    Science.gov (United States)

    Kim, Kyeong Ok; Yuk, Jin-Hee; Jung, Kyung Tae; Kuh Kang, Suk

    2017-04-01

    The real-time typhoon predictions in the Northwest Pacific (NWP) are being distributed by various agencies (for example, KMA, JMA, JTWC, NMC, CWB, HKO and PAGASA). Currently the movement of the typhoon can be predicted with an error of less than 100 km in 48 hours, however it is difficult to the predict of the intensity of the typhoon especially the Rapidly Intensified (RI) Typhoons. The mean occurrence of RI typhoon amounts to 5.4 times a year during 39 years (1977-2015), occupying 21% of typhoons in NWP. Especially the RI typhoon in the Eddy-Rich Northwest Pacific (ER-NWP) occurred 1.8 times a year, covering 29% of typhoons in ER-NWP. A RI typhoon, NEPARTAK (T201601), occurred in July 2016. It was formed in Caroline Islands and moved northwest, straightly heading for Taiwan. However, at the beginning stage many forecasting agencies predicts as move to the Yellow Sea. The accuracy of prediction data of the Typhoon NEPARTAK (T201601) from KMA, JMA and JTWC was compared with the adjusted best-track data from Digital-Typhoon (JMA-RSMC). The sequential prediction data are summarized with 6-hour interval from 3th to 10th July 2016.The JMA prediction of the typhoon track and the JTWC predictions of the maximum wind speed were found to be best. The numerical simulations using WRF model forced with NCEP GFS prediction data and microwave SST is compared. The simulations using one domain (D1), two domains (D2) using a moving nest scheme, and with or without the spectral nudging (-SN) are compared. Comparison of the errors on the track shows the differences of 100 km in 48-hour prediction and200 km in 72-hour prediction on average. The best results on the track prediction are shown in the D2 case of WRF model. However, underestimation of the maximum wind speed of WRF prediction still exists, obviously requiring better understanding of RI-related processes to improve the model prediction.

  17. [Intensified rehabilitation aftercare (IRENA): utilization alongside work and changes in work-related parameters].

    Science.gov (United States)

    Lamprecht, J; Behrens, J; Mau, W; Schubert, M

    2011-06-01

    An aftercare programme following medical rehabilitation may be beneficial in order to reinforce and stabilize the positive effects of rehabilitation and to encourage individual health-related modifications of behaviour and lifestyle. Medical rehabilitation and the aftercare programme of the German Pension Insurance Fund primarily are intended to sustain earning capacity. As part of an evaluation of the Intensified Rehabilitation Aftercare Programme (IRENA) established by the German Pension Insurance Fund, work-related aspects in orthopaedic patients were analyzed based on various data sources. Firstly, the significance of institutional and individual conditions for utilization of IRENA alongside work was of interest. Secondly, the IRENA participants' judgements of the changes of work-related parameters due to the programme were examined, differentiating specifically by extent of earning capacity impairments as well as by particular work problems. The data set used for the analysis is composed of person-related routine data of the German Pension Insurance Fund relative to IRENA records of the year 2007 (n=30 663), interview data from orthopaedic rehabilitation centres providing IRENA (n=225), and questionnaires of IRENA participants (n=750) that were either collected during a broad evaluation of the IRENA programme or provided by the German Pension Insurance Fund. The results show that the compatibility of IRENA and work is facilitated by the institutional conditions. However, differences between inpatient and outpatient settings have to be recognized. The possibilities to participate in IRENA throughout the day frequently are more diverse in an outpatient setting. In contrast to inpatient centres, outpatient rehabilitation centres see clearly better chances for patients to return to work and to participate in IRENA alongside. With respect to the work-related parameters (work ability, periods of sick leave), clear improvements were reported by participants from

  18. Do biomass burning aerosols intensify drought in equatorial Asia during El Niño?

    Directory of Open Access Journals (Sweden)

    M. G. Tosca

    2010-04-01

    in the region intensifies drought stress during El Niño.

  19. Do biomass burning aerosols intensify drought in equatorial Asia during El Niño?

    Energy Technology Data Exchange (ETDEWEB)

    Tosca, M G; Randerson, J; Zender, C S; Flanner, M G; Rasch, Philip J

    2010-04-16

    intensifies drought stress during El Niño.

  20. [Can implementation of intensified perinatal survey be effective in improving the quality of perinatal care?].

    Science.gov (United States)

    Troszyński, Michał

    2010-01-01

    Intensive scientific research and rapid technical progress have influenced the rapid fall in term newborn mortality. At the same time new problems have arisen such as saving the lives of infants with low and very low birth weight. Solving these problems needs reorganization of perinatal care, better equipment, especially in reference units and in outpatient clinics, as well as more intensive staff training. to obtain information whether implementation of intensified perinatal survey of fetus and newborn mortality can improve the quality of perinatal care in Poland. Implementation of the survey based on Central Statistics Office (GUS) data, Ministry of Health MZ-29 section X Document and the author's own studies. In the year 2008 newborn with birth weight less than 2500 g, constituted 6,06% liveborn infants, newborn weighing from 1000 to 2499 g - 5%, those with weight from 500 to 999 g - 0.51% of all live born infants. These figures differ according to voivodeship. The intensive survey concerning birth weight and perinatal mortality indeces in voivodeshipPoland, as well as in individual voivodeships, showed differences between data from the Central Statistics Office and data from the Ministry of Health MZ-29 document. This may be due to different methods of registrating newborn deaths eg. newborns transfered in the first weekoflife from the maternity ward to intensive care neonatal ward or to other specialistic departaments. Another reason for the difference may be discharge of the newborn data according to the place of birth or the mother's place of permanent domicile registration. This causes disturbances in flow of infomation resulting in ineffective analysis of perinatal mortality and of perinatal care evaluation. In the ongoing analysis it was found that in Poland stillbirths occur twice as often as perinatal deaths (4.3 per thousands) stillbirths and 2.15 per thousands perinatal deaths), with significant differences between voivodeships. This makes it

  1. Effects of repetitive or intensified instructions in telephone assisted, bystander cardiopulmonary resuscitation: an investigator-blinded, 4-armed, randomized, factorial simulation trial.

    Science.gov (United States)

    van Tulder, R; Roth, D; Krammel, M; Laggner, R; Heidinger, B; Kienbacher, C; Novosad, H; Chwojka, C; Havel, C; Sterz, F; Schreiber, W; Herkner, H

    2014-01-01

    Compression depth is frequently suboptimal in cardiopulmonary resuscitation (CPR). We investigated effects of intensified wording and/or repetitive target depth instructions on compression depth in telephone-assisted, protocol driven, bystander CPR on a simulation manikin. Thirty-two volunteers performed 10 min of compression only-CPR in a prospective, investigator-blinded, 4-armed, factorial setting. Participants were randomized either to standard wording ("push down firmly 5 cm"), intensified wording ("it is very important to push down 5 cm every time") or standard or intensified wording repeated every 20s. Three dispatchers were randomized to give these instructions. Primary outcome was relative compression depth (absolute compression depth minus leaning depth). Secondary outcomes were absolute distance, hands-off times as well as BORG-scale and nine-hole peg test (NHPT), pulse rate and blood pressure to reflect physical exertion. We applied a random effects linear regression model. Relative compression depth was 35 ± 10 mm (standard) versus 31 ± 11 mm (intensified wording) versus 25 ± 8 mm (repeated standard) and 31 ± 14 mm (repeated intensified wording). Adjusted for design, body mass index and female sex, intensified wording and repetition led to decreased compression depth of 13 (95%CI -25 to -1) mm (p=0.04) and 9 (95%CI -21 to 3) mm (p=0.13), respectively. Secondary outcomes regarding intensified wording showed significant differences for absolute distance (43 ± 2 versus 20 (95%CI 3-37) mm; p=0.01) and hands-off times (60 ± 40 versus 157 (95%CI 63-251) s; p=0.04). In protocol driven, telephone-assisted, bystander CPR, intensified wording and/or repetitive target depth instruction will not improve compression depth compared to the standard instruction. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  2. New spectrofluorometer with pulsed intensified photodiodes array for direct trace determination of actinides and lanthanides in solutions

    International Nuclear Information System (INIS)

    Decambox, P.; Kirsch, B.; Mauchien, P.; Moulin, C.

    1989-01-01

    Actinides and lanthanides in solution at very low level are determined by Time-Resolved Laser-Induced Spectrofluorometry (TRLIS) with pulsed intensified photodiodes array detection. Temporal resolution allows discrimination against short lifetime fluorescence and measurement of fluorescence lifetime in various matrices. The use of laser source leads to excitation selectivity and high sensitivity. Multichannel detection allows to cover the entire wavelength range of interest which leads to emission selectivity and rapidity. These different advantages are present in the newly commercialized spectrofluorometer FLUO 2001 together with specially analytical adapted software. The apparatus and performances obtained for several actinides and lanthanides are presented

  3. Evidence of disturbed sleep and mood state in well-trained athletes during short-term intensified training with and without a high carbohydrate nutritional intervention.

    Science.gov (United States)

    Killer, S C; Svendsen, I S; Jeukendrup, A E; Gleeson, M

    2017-07-01

    Few studies have investigated the effects of exercise training on sleep physiology in well-trained athletes. We investigated changes in sleep markers, mood state and exercise performance in well-trained cyclists undergoing short-term intensified training and carbohydrate nutritional intervention. Thirteen highly-trained male cyclists (age: 25 ± 6y, [Formula: see text]O 2max : 72 ± 5 ml/kg/min) participated in two 9-day periods of intensified training while undergoing a high (HCHO) or moderate (CON) carbohydrate nutritional intervention before, during and after training sessions. Sleep was measured each night via wristwatch actigraphy. Mood state questionnaires were completed daily. Performance was assessed with maximal oxygen uptake ([Formula: see text]. Percentage sleep time fell during intensified training (87.9 ± 1.5 to 82.5 ± 2.3%; p Sleep efficiency decreased during intensified training (83.1 ± 5.3 to 77.8 ± 8.6%; p sleep time was significantly higher in CON than HCHO throughout intensified training. Mood disturbance increased during intensified training and was higher in CON than HCHO (p sleep quality, mood state and maximal exercise performance.

  4. Charge-coupled-device X-ray detector performance model

    Science.gov (United States)

    Bautz, M. W.; Berman, G. E.; Doty, J. P.; Ricker, G. R.

    1987-01-01

    A model that predicts the performance characteristics of CCD detectors being developed for use in X-ray imaging is presented. The model accounts for the interactions of both X-rays and charged particles with the CCD and simulates the transport and loss of charge in the detector. Predicted performance parameters include detective and net quantum efficiencies, split-event probability, and a parameter characterizing the effective thickness presented by the detector to cosmic-ray protons. The predicted performance of two CCDs of different epitaxial layer thicknesses is compared. The model predicts that in each device incomplete recovery of the charge liberated by a photon of energy between 0.1 and 10 keV is very likely to be accompanied by charge splitting between adjacent pixels. The implications of the model predictions for CCD data processing algorithms are briefly discussed.

  5. A Study of Residual Image in Charged-Coupled Device

    Directory of Open Access Journals (Sweden)

    Ho Jin

    2005-12-01

    Full Text Available For an image sensor CCD, electrons can be trapped at the front-side Si-SiO_2 surface interface in a case of exceeding the full well by bright source. Residual images can be made by the electrons remaining in the interface. These residual images are seen in the front-side-illuminated CCDs especially. It is not easy to find a quantitative analysis for this phenomenon in the domestic reports, although it is able to contaminate observation data. In this study, we find residual images in dark frames which were obtained from the front-side-illuminated CCD at Mt. Lemmon Optical Astronomy Observatory (LOAO, and analyze the effect to contaminated observation data by residual charges.

  6. Elevated Serum Hepcidin Levels during an Intensified Training Period in Well-Trained Female Long-Distance Runners

    Directory of Open Access Journals (Sweden)

    Aya Ishibashi

    2017-03-01

    Full Text Available Iron is essential for providing oxygen to working muscles during exercise, and iron deficiency leads to decreased exercise capacity during endurance events. However, the mechanism of iron deficiency among endurance athletes remains unclear. In this study, we compared iron status between two periods involving different training regimens. Sixteen female long-distance runners participated. Over a seven-month period, fasting blood samples were collected during their regular training period (LOW; middle of February and during an intensified training period (INT; late of August to determine blood hematological, iron, and inflammatory parameters. Three-day food diaries were also assessed. Body weight and lean body mass did not differ significantly between LOW and INT, while body fat and body fat percentage were significantly lower in INT (p < 0.05. Blood hemoglobin, serum ferritin, total protein, and iron levels, total iron-binding capacity, and transferrin saturation did not differ significantly between the two periods. Serum hepcidin levels were significantly higher during INT than LOW (p < 0.05. Carbohydrate and iron intakes from the daily diet were significantly higher during INT than LOW (p < 0.05. In conclusion, an elevated hepcidin level was observed during an intensified training period in long-distance runners, despite an apparently adequate daily intake of iron.

  7. Impacts of aeration management and polylactic acid addition on dissolved organic matter characteristics in intensified aquaponic systems.

    Science.gov (United States)

    Wu, Haiming; Zou, Yina; Lv, Jialong; Hu, Zhen

    2018-08-01

    Aquaponics as a potential alternative for conventional aquaculture industry has increasingly attracted worldwide attention in recent years. However, the sustainable application of aquaponics is facing a growing challenge. In particular, there is a pressing need to better understand and control the accumulation of dissolved organic matter (DOM) in aquaponics with the aim of optimizing nitrogen utilization efficiency. This study was aiming for assessing the characteristics of DOM in the culture water and the relationship with the nitrogen transformations in different intensified aquaponic systems with hydroponic aeration supplement and polylactic acid (PLA) addition. Two enhancing attempts altered the quantity of DOM in aquaponic systems significantly with a varying DOM content of 21.98-45.65 mg/L. The DOM could be represented by four identified fluorescence components including three humic -like materials (83-86%) and one tryptophan-like substance (14-17%). The fluorescence intensities of humic acid-like components were decreased significantly after the application of intensifying strategies, which indicating that two enhancing attempts possibly affected humic acid-like fluorescence. Variation of optical indices also suggested the reductions of water DOM which could be impacted by the enhancing nitrogen treatment processes. These findings will benefit the potential applications and sustainable operation of these strategies in aquaponics. Copyright © 2018 Elsevier Ltd. All rights reserved.

  8. Measurement of the uniformity of X-ray image-intensifier television systems and of the system components

    International Nuclear Information System (INIS)

    Cooney, P.; Maher, K.P.; Malone, J.F.

    1989-01-01

    Uniformity is a well defined term used to describe the response of a gamma camera to a ''uniform'' radiation input. A similar quantity is required in the specification of the image-intensifier (II) television (TV) chains used in fluoroscopic imaging, particularly in vascular, cardiac and digital applications. This paper presents work on the use of the National Electrical Manufacturers' Association definition of uniformity for gamma cameras and its refinement for application in the field with II-TV chains as whole systems. The methods of measurement employed using on-site high-quality videotape recording combined with an off-site and off-line digital image processor are described. The impact of noise reduction and matrix size on the results in outlined. The contribution of individual components of the chain to the non-uniformity have also been assessed in detail using methods of measurement and definitions specifically developed to be suitable for application in the hospital environment by an experienced physicist. The methods and results for (i) the X-ray beam, (ii) the image intensifier and (iii) the TV system are presented. These methods have been tested by applying them to a sample of 10 II-TV systems in routine hospital use and the results are reported. (author)

  9. Measurement of the uniformity of X-ray image-intensifier television systems and of the system components

    International Nuclear Information System (INIS)

    Cooney, P.; Maher, K.P.; Malone, J.F.

    1989-01-01

    This paper presents work on the use of the National Electrical Manufacturers' Association definition of uniformity for gamma cameras and its refinement for application in the field with image intensified television (II-TV) chains as whole systems. Methods of measurement employed using on-site high-quality videotape recording combined with an off-site and off-line digital image processor are described. Impact of noise reduction and matrix size on the results is outlined. The contribution of individual components of the chain to the non-uniformity have also been assessed in detail using methods of measurement and definitions specifically developed to be suitable for application in the hospital environment by an experienced physicist. The methods and results for (i) the X-ray beam, (ii) the image intensifier and (iii) the TV system are presented. These methods have been tested by applying them to a sample of 10 II-TV systems in routine hospital use and results are reported. (author)

  10. Therapeutic inertia and intensified treatment in diabetes mellitus prescription patterns: A nationwide population-based study in Taiwan.

    Science.gov (United States)

    Huang, Li-Ying; Yeh, Hseng-Long; Yang, Ming-Chin; Shau, Wen-Yi; Su, Syi; Lai, Mei-Shu

    2016-12-01

    Objective To measure therapeutic inertia by characterizing prescription patterns using secondary data obtained from the nationwide diabetes mellitus pay-for-performance (DM-P4P) programme in Taiwan. Methods Using reimbursement claims from Taiwan's National Health Insurance Research Database, a nationwide retrospective cohort study was undertaken of patients with diabetes mellitus who participated in the DM-P4P programme from 2006-2008. Glycosylated haemoglobin results were used to evaluate modifications in therapy in response to poor diabetes control. Prescription patterns were used to assign patients to either a therapeutic inertia group or an intensified treatment group. Therapeutic inertia was defined as the failure to act on a known problem. Results The research sample comprised of 168 876 patients with diabetes mellitus who had undergone 899 135 tests. Of these, 37.4% (336 615 visits) of prescriptions were for a combination of two types of drug and 27.7% (248 788 visits) were for a combination of three types of drug. The proportion of patients in the intensified therapy group who were prescribed more than two types of drug was considerably higher than that in the therapeutic inertia group. Conclusion In many cases in the therapeutic inertia group only a single type of hypoglycaemic drug was prescribed or the dosage remained unchanged.

  11. Sensitometric effects of varying the intensifying screens used with Agfa Dentus ST8G and RP6 panoramic radiographic films.

    Science.gov (United States)

    Wakoh, M; Farman, A G; Scarfe, W C; Kitagawa, H; Kuroyanagi, K

    1997-07-01

    To compare the sensitometric effects and information yield of varying the intensifying screens used with both Dentus ST8G and RP6 Agfa Gevaert, Dormagen, Germany panoramic radiographic films. Four screen-film combinations were employed for each of the two film types. The screens used were blue fluorescing PX-III (Kasei Optonix, Tokyo, Japan) and Special (Siemens AG, Bensheim, Germany), as well as green fluorescing Lanex Regular (Eastman Kodak, Rochester, NY, USA) and Trimax T16 (3M, Mineapolis, Minnesota, USA). The density response for each screen-film combination was evaluated using the characteristic curves generated. Information yield, as determined by the radiographic detection of defects in an aluminium test object, was evaluated by nine observers. The characteristic curves for ST8G were different when green and blue fluorescing screens were used; however, those for RP6 varied little irrespective of the choice of intensifying screens. Observers were able to perceive defects at significantly lower radiation exposures for ST8G combined with green fluorescing screens compared with blue emitting screens. RP6 with all screen combinations provided similar image detail perceptibility at comparable exposures with ST8G with green-fluorescing screens. RP6 is suitable for use with either the spectrally matched blue emitting screens or green-emitting screens. ST8G radiographic film should always be matched to rare earth screens.

  12. New approaches to determine fatigue in elite athletes during intensified training: Resting metabolic rate and pacing profile.

    Directory of Open Access Journals (Sweden)

    Amy L Woods

    Full Text Available Elite rowers complete a high volume of training across a number of modalities to prepare for competition, including periods of intensified load, which may lead to fatigue and short-term performance decrements. As yet, the influence of substantial fatigue on resting metabolic rate (RMR and exercise regulation (pacing, and their subsequent utility as monitoring parameters, has not been explicitly investigated in elite endurance athletes.Ten National-level rowers completed a four-week period of intensified training. RMR, body composition and energy intake were assessed PRE and POST the four-week period using indirect calorimetry, Dual-Energy X-Ray Densitometry (DXA, and three-day food diary, respectively. On-water rowing performance and pacing strategy was evaluated from 5 km time trials. Wellness was assessed weekly using the Multicomponent Training Distress Scale (MTDS.Significant decreases in absolute (mean ± SD of difference, p-value: -466 ± 488 kJ.day-1, p = 0.01 and relative RMR (-8.0 ± 8.1 kJ.kg.FFM-1, p = 0.01 were observed. Significant reductions in body mass (-1.6 ± 1.3 kg, p = 0.003 and fat mass (-2.2 ± 1.2 kg, p = 0.0001 were detected, while energy intake was unchanged. On-water 5 km rowing performance worsened (p < 0.05 and an altered pacing strategy was evident. Fatigue and total mood disturbance significantly increased across the cycle (p < 0.05, and trends were observed for reduced vigour and increased sleep disturbance (p < 0.1.Four weeks of heavy training decreased RMR and body composition variables in elite rowers and induced substantial fatigue, likely related to an imbalance between energy intake and output. This study demonstrates that highly experienced athletes do not necessarily select the correct energy intake during periods of intensified training, and this can be assessed by reductions in RMR and body composition. The shortfall in energy availability likely affected recovery from training and altered 5 km time trial

  13. Exposure time, running and skill-related performance in international u20 rugby union players during an intensified tournament.

    Directory of Open Access Journals (Sweden)

    Christopher J Carling

    Full Text Available This study investigated exposure time, running and skill-related performance in two international u20 rugby union teams during an intensified tournament: the 2015 Junior World Rugby Championship.Both teams played 5 matches in 19 days. Analyses were conducted using global positioning system (GPS tracking (Viper 2™, Statsports Technologies Ltd and event coding (Opta Pro®.Of the 62 players monitored, 36 (57.1% participated in 4 matches and 23 (36.5% in all 5 matches while player availability for selection was 88%. Analyses of team running output (all players completing >60-min play showed that the total and peak 5-minute high metabolic load distances covered were likely-to-very likely moderately higher in the final match compared to matches 1 and 2 in back and forward players. In individual players with the highest match-play exposure (participation in >75% of total competition playing time and >75-min in each of the final 3 matches, comparisons of performance in matches 4 and 5 versus match 3 (three most important matches reported moderate-to-large decreases in total and high metabolic load distance in backs while similar magnitude reductions occurred in high-speed distance in forwards. In contrast, skill-related performance was unchanged, albeit with trivial and unclear changes, while there were no alterations in either total or high-speed running distance covered at the end of matches.These findings suggest that despite high availability for selection, players were not over-exposed to match-play during an intensified u20 international tournament. They also imply that the teams coped with the running and skill-related demands. Similarly, individual players with the highest exposure to match-play were also able to maintain skill-related performance and end-match running output (despite an overall reduction in the latter. These results support the need for player rotation and monitoring of performance, recovery and intervention strategies during

  14. Exposure time, running and skill-related performance in international u20 rugby union players during an intensified tournament

    Science.gov (United States)

    Carling, Christopher J.; Flanagan, Eamon; O’Doherty, Pearse; Piscione, Julien

    2017-01-01

    Purpose This study investigated exposure time, running and skill-related performance in two international u20 rugby union teams during an intensified tournament: the 2015 Junior World Rugby Championship. Method Both teams played 5 matches in 19 days. Analyses were conducted using global positioning system (GPS) tracking (Viper 2™, Statsports Technologies Ltd) and event coding (Opta Pro®). Results Of the 62 players monitored, 36 (57.1%) participated in 4 matches and 23 (36.5%) in all 5 matches while player availability for selection was 88%. Analyses of team running output (all players completing >60-min play) showed that the total and peak 5-minute high metabolic load distances covered were likely-to-very likely moderately higher in the final match compared to matches 1 and 2 in back and forward players. In individual players with the highest match-play exposure (participation in >75% of total competition playing time and >75-min in each of the final 3 matches), comparisons of performance in matches 4 and 5 versus match 3 (three most important matches) reported moderate-to-large decreases in total and high metabolic load distance in backs while similar magnitude reductions occurred in high-speed distance in forwards. In contrast, skill-related performance was unchanged, albeit with trivial and unclear changes, while there were no alterations in either total or high-speed running distance covered at the end of matches. Conclusions These findings suggest that despite high availability for selection, players were not over-exposed to match-play during an intensified u20 international tournament. They also imply that the teams coped with the running and skill-related demands. Similarly, individual players with the highest exposure to match-play were also able to maintain skill-related performance and end-match running output (despite an overall reduction in the latter). These results support the need for player rotation and monitoring of performance, recovery and

  15. Elevated Serum Hepcidin Levels during an Intensified Training Period in Well-Trained Female Long-Distance Runners.

    Science.gov (United States)

    Ishibashi, Aya; Maeda, Naho; Sumi, Daichi; Goto, Kazushige

    2017-03-14

    Iron is essential for providing oxygen to working muscles during exercise, and iron deficiency leads to decreased exercise capacity during endurance events. However, the mechanism of iron deficiency among endurance athletes remains unclear. In this study, we compared iron status between two periods involving different training regimens. Sixteen female long-distance runners participated. Over a seven-month period, fasting blood samples were collected during their regular training period (LOW; middle of February) and during an intensified training period (INT; late of August) to determine blood hematological, iron, and inflammatory parameters. Three-day food diaries were also assessed. Body weight and lean body mass did not differ significantly between LOW and INT, while body fat and body fat percentage were significantly lower in INT ( p daily diet were significantly higher during INT than LOW ( p daily intake of iron.

  16. Effects of oxygen delivery, dietary nitrate, intensified training and prior exercise on oxygen uptake kinetics and performance in humans

    DEFF Research Database (Denmark)

    Christensen, Peter Møller

    benefits from supplementing with nitrate to improve exercise efficiency and performance in endurance trained subjects. Furthermore it appears difficult to improve VO2 kinetics with intensified training in trained athletes; however intense exercise can amplify the VO2 response during subsequent high......In response to an increase in the metabolic demand the oxygen uptake (VO2) increases in an exponential fashion in exercising muscles and stabilizes after 1-2 min eventually reaching a plateau or steady state where the energy demand is matched by the l vel of VO2. VO2 kinetics describes the distinct...... phases of the VO2 response at the onset of exercise. Fast VO2 kinetics are considered to be beneficial in intense endurance sports with competitions lasting ~2-8 min, whereas low VO2 at steady state (high efficiency) is considered beneficial especially in events of longer duration. To improve...

  17. X-ray diagnostic installation with an image intensifier TV chain and a dose rate control device

    Energy Technology Data Exchange (ETDEWEB)

    Duemmling, K; Schott, O

    1977-04-28

    The person performing the examination can key up the dose rate briefly via the X-ray tube current, e.g., if the movement of a contrast medium is to be observed on the video screen and only certain phases in this movement, which are of diagnostic significance, are to be viewed more closely. The upward change necessary to reduce quantum noise by a certain factor is made by means of a switch. This at the same time results in a reduction of brightness (over-exposure) of the X-ray image on the video screen by actuating an aperture system between the image intensifier, and the TV camera. To prevent the X-ray tube from being overloaded during key-up of the dose rate, a time limit switch is installed in the control system.

  18. A prototype detector using the neutron image intensifier and multi-anode type photomultiplier tube for pulsed neutron imaging

    International Nuclear Information System (INIS)

    Ishikawa, Hirotaku; Sato, Hirotaka; Hara, Kaoru Y.; Kamiyama, Takashi

    2016-01-01

    We developed a neutron two-dimensional (2-D) detector for pulsed neutron imaging as a prototype detector, which was composed of a neutron image intensifier and a multi-anode type photomultiplier tube. A neutron transmission spectrum of α-Fe plate was measured by the prototype detector, and compared with the one measured by a typical neutron 2-D detector. The spectrum was in reasonable agreement with the one measured by the typical detector in the neutron wavelength region above 0.15 nm. In addition, a neutron transmission image of a cadmium indicator was obtained by the prototype detector. The usefulness of the prototype detector for pulsed neutron imaging was demonstrated. (author)

  19. Importance of soil nitrogen and select intensifying measures in the soil-plant-fertilizer system demonstrated in sugar beets

    International Nuclear Information System (INIS)

    Rauhe, K.; Sielaff, B.; Barth, F.J.

    1981-01-01

    Sugar beets were gradually fertilized with 15 N-labelled nitrogen fertilizer without or in combination with irrigation. To gain optimum crop yields 180 - 200 kg/ha fertilizer nitrogen were required. Within the range of maximum yield the total nitrogen uptake amounted to 300 - 360 kg/ha under conditions of irrigation. Nitrogen was taken up from the fertilizer by 40% and from the soil by 60%. The immobilization rate of fertilizer nitrogen was near 30% after 2 years of vegetation. Only 33% and 25%, resp., of soil nitrogen could be replaced by fertilizing without and combined with irrigation, resp. It was shown that despite of increased application of the main intensifying factors, nitrogen and water, the soil nitrogen was mineralized intensively

  20. Development of an image intensifier-TV digital imaging system with a multiple-slit scanning x-ray beam

    International Nuclear Information System (INIS)

    Kume, Y.; Doi, K.

    1986-01-01

    The authors are developing a new digital x-ray imaging system employing a multiple-slit assembly (MSA) and an image intensifier (II)-TV digital system. The final image consisting of primary radiation is digitally reconstructed from multiple slit images obtained with the MSA. This system can significantly reduce the scattered radiation from an object and the veiling glare from II-TV system. The quality of the reconstructed image is related to many parameters, such as slit width, the number of image frames, and the image reconstruction algorithm. They present the effect of these various parameters on basic imaging properties and the practicability of the method in comparison with conventional wide beam imaging

  1. Uses of microchannel plate intensified detectors for imaging applications in the X-ray, EUV and visible wavelength regions

    International Nuclear Information System (INIS)

    Read, P.D.; Carter, M.K.; Pike, C.D.; Harrison, R.A.; Kent, B.J.; Swinyard, B.M.; Patchett, B.E.; Redfern, R.M.; Shearer, A.; Colhoun, M.

    1997-01-01

    The Rutherford Appleton laboratory photon counting detector (RALPCD) has been refined to meet project requirements for a flexible imaging arrangement with applications at X-ray, EUV and visible wavelengths. The basic detector design comprises commercially available high gain microchannel plate intensifiers fibre optically coupled to CID or CCD cameras, to form a modular detector arrangement with the appropriate RAL detection and centroiding software. Frames of data from the cameras are detected and centroided in a transputer or C40 parallel processor array where correction algorithms use look up tables to produce pattern free images at high resolution. Data from completed applications are used to illustrate the performance and future advances are discussed. (orig.)

  2. Effect of process intensifying parameters on the hydrodynamic cavitation based degradation of commercial pesticide (methomyl) in the aqueous solution.

    Science.gov (United States)

    Raut-Jadhav, Sunita; Saini, Daulat; Sonawane, Shirish; Pandit, Aniruddha

    2016-01-01

    Methomyl, a carbamate pesticide, is classified as a pesticide of category-1 toxicity and hence shows harmful effects on both human and aquatic life. In the present work, the degradation of methomyl has been studied by using hydrodynamic cavitation reactor (HC) and its combination with intensifying agents such as H2O2, fenton reagent and ozone (hybrid processes). Initially, the optimization of operating parameters such pH and inlet pressure to the cavitating device (circular venturi) has been carried out for maximizing the efficacy of hydrodynamic cavitation. Further degradation study of methomyl by the application of hybrid processes was carried out at an optimal pH of 2.5 and the optimal inlet pressure of 5 bar. Significant synergetic effect has been observed in case of all the hybrid processes studied. Synergetic coefficient of 5.8, 13.41 and 47.6 has been obtained by combining hydrodynamic cavitation with H2O2, fenton process and ozone respectively. Efficacy of individual and hybrid processes has also been obtained in terms of energy efficiency and extent of mineralization. HC+Ozone process has proved to be the most effective process having highest synergetic coefficient, energy efficiency and the extent of mineralization. The study has also encompassed the identification of intermediate by-products generated during the degradation and has proposed the probable degradation pathway. It has been conclusively established that hydrodynamic cavitation in the presence of intensifying agents can effectively be used for complete degradation of methomyl. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. Low carbohydrate, high fat diet impairs exercise economy and negates the performance benefit from intensified training in elite race walkers

    Science.gov (United States)

    Ross, Megan L.; Garvican‐Lewis, Laura A.; Welvaert, Marijke; Heikura, Ida A.; Forbes, Sara G.; Mirtschin, Joanne G.; Cato, Louise E.; Strobel, Nicki; Sharma, Avish P.; Hawley, John A.

    2017-01-01

    Key points Three weeks of intensified training and mild energy deficit in elite race walkers increases peak aerobic capacity independent of dietary support.Adaptation to a ketogenic low carbohydrate, high fat (LCHF) diet markedly increases rates of whole‐body fat oxidation during exercise in race walkers over a range of exercise intensities.The increased rates of fat oxidation result in reduced economy (increased oxygen demand for a given speed) at velocities that translate to real‐life race performance in elite race walkers.In contrast to training with diets providing chronic or periodised high carbohydrate availability, adaptation to an LCHF diet impairs performance in elite endurance athletes despite a significant improvement in peak aerobic capacity. Abstract We investigated the effects of adaptation to a ketogenic low carbohydrate (CHO), high fat diet (LCHF) during 3 weeks of intensified training on metabolism and performance of world‐class endurance athletes. We controlled three isoenergetic diets in elite race walkers: high CHO availability (g kg−1 day−1: 8.6 CHO, 2.1 protein, 1.2 fat) consumed before, during and after training (HCHO, n = 9); identical macronutrient intake, periodised within or between days to alternate between low and high CHO availability (PCHO, n = 10); LCHF (diets providing chronic or periodised high‐CHO availability, and despite a significant improvement in V˙O2 peak , adaptation to the topical LCHF diet negated performance benefits in elite endurance athletes, in part due to reduced exercise economy. PMID:28012184

  4. Rationale and design of the GUIDE-IT study: Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure.

    Science.gov (United States)

    Felker, G Michael; Ahmad, Tariq; Anstrom, Kevin J; Adams, Kirkwood F; Cooper, Lawton S; Ezekowitz, Justin A; Fiuzat, Mona; Houston-Miller, Nancy; Januzzi, James L; Leifer, Eric S; Mark, Daniel B; Desvigne-Nickens, Patrice; Paynter, Gayle; Piña, Ileana L; Whellan, David J; O'Connor, Christopher M

    2014-10-01

    The GUIDE-IT (Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure) study is designed to determine the safety, efficacy, and cost-effectiveness of a strategy of adjusting therapy with the goal of achieving and maintaining a target N-terminal pro-B-type natriuretic peptide (NT-proBNP) level of levels provide key prognostic information in patients with HF. Therapies proven to improve outcomes in patients with HF are generally associated with decreasing levels of NPs, and observational data show that decreases in NP levels over time are associated with favorable outcomes. Results from smaller prospective, randomized studies of this strategy thus far have been mixed, and current guidelines do not recommend serial measurement of NP levels to guide therapy in patients with HF. GUIDE-IT is a prospective, randomized, controlled, unblinded, multicenter clinical trial designed to randomize approximately 1,100 high-risk subjects with systolic HF (left ventricular ejection fraction ≤40%) to either usual care (optimized guideline-recommended therapy) or a strategy of adjusting therapy with the goal of achieving and maintaining a target NT-proBNP level of study are followed up at regular intervals and after treatment adjustments for a minimum of 12 months. The primary endpoint of the study is time to cardiovascular death or first hospitalization for HF. Secondary endpoints include time to cardiovascular death and all-cause mortality, cumulative mortality, health-related quality of life, resource use, cost-effectiveness, and safety. The GUIDE-IT study is designed to definitively assess the effects of an NP-guided strategy in high-risk patients with systolic HF on clinically relevant endpoints of mortality, hospitalization, quality of life, and medical resource use. (Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure [GUIDE-IT]; NCT01685840). Copyright © 2014 American College of Cardiology Foundation

  5. Development and evaluation of a novel low power, high frequency piezoelectric-based ultrasonic reactor for intensifying the transesterification reaction

    Directory of Open Access Journals (Sweden)

    Mortaza Aghbashlo

    2016-12-01

    Full Text Available In this study, a novel low power, high frequency piezoelectric-based ultrasonic reactor was developed and evaluated for intensifying the transesterification process. The reactor was equipped with an automatic temperature control system, a heating element, a precise temperature sensor, and a piezoelectric-based ultrasonic module. The conversion efficiency and specific energy consumption of the reactor were examined under different operational conditions, i.e., reactor temperature (40‒60 °C, ultrasonication time (6‒10 min, and alcohol/oil molar ratio (4:1‒8:1. Transesterification of waste cooking oil (WCO was performed in the presence of a base-catalyst (potassium hydroxide using methanol. According to the obtained results, alcohol/oil molar ratio of 6:1, ultrasonication time of 10 min, and reactor temperature of 60 °C were found as the best operational conditions. Under these conditions, the reactor converted WCO to biodiesel with a conversion efficiency of 97.12%, meeting the ASTM standard satisfactorily, while the lowest specific energy consumption of 378 kJ/kg was also recorded. It should be noted that the highest conversion efficiency of 99.3 %, achieved at reactor temperature of 60 °C, ultrasonication time of 10 min, and alcohol/oil molar ratio of 8:1, was not favorable as the associated specific energy consumption was higher at 395 kJ/kg. Overall, the low power, high frequency piezoelectric-based ultrasonic module could be regarded as an efficient and reliable technology for intensifying the transesterification process in terms of energy consumption, conversion efficiency, and processing time, in comparison with high power, low frequency ultrasonic system reported previously. Finally, this technology could also be considered for designing, developing, and retrofitting chemical reactors being employed for non-biofuel applications as well.

  6. Acceleration of peat drying by intensifying the heat and mass transfer; Turpeen kuivumisen nopeuttaminen laemmoen- ja aineensiirtoa tehostamalla

    Energy Technology Data Exchange (ETDEWEB)

    Hillebrand, K.

    1996-12-31

    The efficiency of peat production can be increased by intensifying peat drying. To intensify drying one has to know the effects of the different factors affecting the heat and mass transfer in the drying layer and in the soil. The objective of the study is to increase the degree of utilization of solar energy in drying of peat from the present level of 30% to 40% of the total incoming solar energy. In this way it is possible to reduce the peat production costs about 10%. A numerical drying model has been developed which describes the transfer of liquid water, water vapor and heat in the drying layer and in the soil. In addition, the interaction between the atmosphere and the drying layer, as well as the rainfall interception by the layer, infiltration, evaporation, and drainage have been taking into account. Daily input requirements include global solar radiation, air temperature and relative humidity, wind speed and precipitation. In addition to the weather data one has to know the characteristics of the drying layer and the soil. The numerical drying model was also used to study the effect of soil frost on peat drying and the possibilities to hinder the frost formation. Producing peat on the field which is still partly frozen, the drying of peat takes 10 - 25% longer time than under normal conditions, which means 5 - 25 hours longer drying period. By forming a porous, insulating layer on the top of the soil surface, one can hinder the frost formation significantly. Raising the groundwater level prevents, however, only a little the frost formation in peat soil

  7. Intensified Sampling in Response to a Salmonella Heidelberg Outbreak Associated with Multiple Establishments Within a Single Poultry Corporation.

    Science.gov (United States)

    Green, Alice; Defibaugh-Chavez, Stephanie; Douris, Aphrodite; Vetter, Danah; Atkinson, Richard; Kissler, Bonnie; Khroustalev, Allison; Robertson, Kis; Sharma, Yudhbir; Becker, Karen; Dessai, Uday; Antoine, Nisha; Allen, Latasha; Holt, Kristin; Gieraltowski, Laura; Wise, Matthew; Schwensohn, Colin

    2018-03-01

    On June 28, 2013, the Food Safety and Inspection Service (FSIS) was notified by the Centers for Disease Control and Prevention (CDC) of an investigation of a multistate cluster of illnesses of Salmonella enterica serovar Heidelberg. Since case-patients in the cluster reported consumption of a variety of chicken products, FSIS used a simple likelihood-based approach using traceback information to focus on intensified sampling efforts. This article describes the multiphased product sampling approach taken by FSIS when epidemiologic evidence implicated chicken products from multiple establishments operating under one corporation. The objectives of sampling were to (1) assess process control of chicken slaughter and further processing and (2) determine whether outbreak strains were present in products from these implicated establishments. As part of the sample collection process, data collected by FSIS personnel to characterize product included category (whole chicken and type of chicken parts), brand, organic or conventional product, injection with salt solutions or flavorings, and whether product was skinless or skin-on. From the period September 9, 2013, through October 31, 2014, 3164 samples were taken as part of this effort. Salmonella percent positive declined from 19.7% to 5.3% during this timeframe as a result of regulatory and company efforts. The results of intensified sampling for this outbreak investigation informed an FSIS regulatory response and corrective actions taken by the implicated establishments. The company noted that a multihurdle approach to reduce Salmonella in products was taken, including on-farm efforts such as environmental testing, depopulation of affected flocks, disinfection of affected houses, vaccination, and use of various interventions within the establishments over the course of several months.

  8. 用新型活化剂强化原油蒸馏过程的研究%INTENSIFYING DISTILLATION OF CRUDE OIL BY USING NEW ACTIVATOR

    Institute of Scientific and Technical Information of China (English)

    刘红研; 沙峰; 詹亚力; 朱建华

    2001-01-01

    By using activator to change the state of crude oil and to diminish the size of dispersed phase,mass transfer in distillation process is intensified and distillate yield is increased.In this work,the new activators R1 and R2 were used as the additives respectively,and the intensifying effects to Daqing crude oil were examined at different concentrations and liquid phase temperatures by means of simple distillation and TBP distillation.The interaction mechanisms between the new activators and the crude oil or residues were analyzed,the intensifying effects by the new activators were also studied.Finally,the conceptual technique of "chemical intensification distillation”was put forward.

  9. X-ray image intensifier for cardiovascular diagnosis. Development of RTP 9203 B-P4 and evaluation of image quality

    Energy Technology Data Exchange (ETDEWEB)

    Obata, Y; Suzuki, A; Noji, T; Harao, N [Toshiba Corp., Kawasaki, Kanagawa (Japan)

    1979-07-01

    The high utility of 35-mm cine fluorography with high-quality X-ray image intensifier has recently been acknowledged in the field of cardiovascular diagnosis. The newly developed 9-inch dual-field X-ray image intensifier is particularly suitable for 35-mm cinefluorography. The main characteristics of this tube are the increased contrast, brightness and resolution of images and the reduced quantum noise. These characteristics are caused by the CsI input phosphor screen which has a ''light-guide effect'', a high-sensitivity photocathode and a dark output screen. The tube is equipped with a high-voltage power supply with high reliability.

  10. Effect of 2-wk intensified training and inactivity on muscle Na+/K+ pump expression, phospholemman (FXYD1) phosphorylation and performance in soccer players

    DEFF Research Database (Denmark)

    Thomassen, Martin; Christensen, Peter Møller; Gunnarsson, Thomas Gunnar Petursson

    2010-01-01

    The present study examined muscle adaptations and alterations in performance of highly trained soccer players with intensified training or training cessation. Eighteen elite soccer players were for a 2-wk period assigned to either a group which performed high intensity training with a reduction....... The present data suggest that short-term intensified training even for trained soccer players can increase muscle Na(+)/K(+) pump alpha2 isoform expression and that cessation of training for two weeks does not affect the expression of Na(+)/K(+) pump isoforms. Resting phosphorylation status of the Na...

  11. Concept Formation in Environmental Education: 14-Year Olds' Work on the Intensified Greenhouse Effect and the Depletion of the Ozone Layer. Research Report

    Science.gov (United States)

    Osterlind, Karolina

    2005-01-01

    A case study is presented describing the work of three pupils in the upper level of compulsory school. The pupils were learning about the intensified greenhouse effect and the depletion of the ozone layer. In their work, the need for certain domain-specific knowledge becomes apparent; for example, understanding such concepts as photosynthesis,…

  12. Influence of Intensified Supervision by Health Care Inspectorates on Online Patient Ratings of Hospitals: A Multilevel Study of More Than 43,000 Online Ratings

    NARCIS (Netherlands)

    Kool, R.B.; Kleefstra, S.M.; Borghans, H.J.; Atsma, F.; Belt, T.H. van de

    2016-01-01

    BACKGROUND: In the Netherlands, hospitals with quality or safety issues are put under intensified supervision by the Dutch Health Care Inspectorate, which involves frequent announced and unannounced site visits and other measures. Patient rating sites are an upcoming phenomenon in health care.

  13. Deconvolution of mixture spectra and increased throughput of Peptide identification by utilization of intensified complementary ions formed in tandem mass spectrometry

    DEFF Research Database (Denmark)

    Kryuchkov, Fedor; Verano-Braga, Thiago; Hansen, Thomas Aarup

    2013-01-01

    -resolution orbitrap mass spectrometry, an increase in the number of peptide identifications was obtained relative to the original CAD MS/MS spectra when intensified golden complementary (+18.6%) and CAD complementary pairs (+17.2%) were submitted to the Mascot search engine. This also exceeded the results obtained...

  14. Influence of phantom and tube voltage in fluoroscopy on image intensifier (I.I.) incident dose rate

    International Nuclear Information System (INIS)

    Seguchi, Shigenobu; Ishikawa, Yoshinobu; Kuwahara, Kazuyoshi; Morita, Miki; Mizuno, Shouta; Nakamura, Akio

    1999-01-01

    We examined the influence of phantoms and tube voltage in fluoroscopy on the image intensifier (I.I.) conversion factor. We used 20-cm-thick acrylic resin, 20 mm aluminum, and 1.5 mm copper, which are generally used as phantoms in the measurement of I.I. incident dose rate. We measured I.I. incident dose rate and conversion factor under conditions in which the range of tube voltage was from 60 kV to 120 kV. The result showed that the conversion factor is influenced by the type of phantom, with copper showing the highest value, aluminum second, and acrylic the smallest under the same condition of aluminum at half value layer. It was determined that conversion factor depends on tube voltage and has peaks from 80-100 kV. The location and height of the peak are influenced by the type of phantom. Therefore, I.I. incident dose rate is influenced by both the type of phantom and tube voltage under automatic brightness control fluoroscopy. Unification of phantoms and tube voltage is necessary for long-term evaluation of I.I. incident dose rate. (author)

  15. The epidemiology of Plasmodium vivax and Plasmodium falciparum malaria in China, 2004-2012: from intensified control to elimination.

    Science.gov (United States)

    Zhang, Qian; Lai, Shengjie; Zheng, Canjun; Zhang, Honglong; Zhou, Sheng; Hu, Wenbiao; Clements, Archie C A; Zhou, Xiao-Nong; Yang, Weizhong; Hay, Simon I; Yu, Hongjie; Li, Zhongjie

    2014-11-03

    In China, the national malaria elimination programme has been operating since 2010. This study aimed to explore the epidemiological changes in patterns of malaria in China from intensified control to elimination stages. Data on nationwide malaria cases from 2004 to 2012 were extracted from the Chinese national malaria surveillance system. The secular trend, gender and age features, seasonality, and spatial distribution by Plasmodium species were analysed. In total, 238,443 malaria cases were reported, and the proportion of Plasmodium falciparum increased drastically from population. The areas affected by Plasmodium vivax malaria shrunk, while areas affected by P. falciparum malaria expanded from 294 counties in 2004 to 600 counties in 2012. This study demonstrated that malaria has decreased dramatically in the last five years, especially since the Chinese government launched a malaria elimination programme in 2010, and areas with reported falciparum malaria cases have expanded over recent years. These findings suggest that elimination efforts should be improved to meet these changes, so as to achieve the nationwide malaria elimination goal in China in 2020.

  16. Intensified training increases salivary free light chains in trained cyclists: Indication that training volume increases oral inflammation.

    Science.gov (United States)

    Heaney, Jennifer L J; Killer, Sophie C; Svendsen, Ida S; Gleeson, Michael; Campbell, John P

    2018-05-01

    Periods of short-term intensified training (IT) are often used by athletes during training cycles over the season and undergoing phases of increased physical stress may impact upon the immune system. This study investigated the effects of a period of IT on free light chains (FLCs) in saliva - an emerging immune biomarker of oral inflammation - and matched serum samples in well-trained athletes. It also examined if IT influences basal FLC levels and FLC flux during acute exercise. Highly trained male cyclists (n = 10) underwent a 9-day period of IT; before and after IT participants performed a 1 h time trial (TT) on a cycle ergometer, with blood and saliva samples collected pre- and post-exercise. FLCs were assessed in serum and saliva, and IgG, IgA, IgM and creatinine were also measured in serum. Weekly training volume increased by 143% (95% CI 114-172%), p training. Following IT, the cyclists demonstrated higher salivary FLC levels. Both salivary lambda FLC concentrations (p training, and we show for the first time that FLCs may have utility as a marker of exercise stress and oral health status. Copyright © 2018 Elsevier Inc. All rights reserved.

  17. ALGORITHM OF DETERMINATION OF POWER AND ENERGY INDEXES OF SCREW INTENSIFIER ON THE BULLDOZER WORKING EQUIPMENT AT TRENCH REFILLINGS

    Directory of Open Access Journals (Sweden)

    KROL R. N.

    2016-03-01

    Full Text Available Raising of problem. A bulldozer work at trench refilings is conducted by cyclic, machine shuttle motions that increases a right-of-way; increasing of time charges, fuel and labour by the side of the continuous refilling method. Besides the indicated defects gets worse also the quality of the trench refilling: the uneven soil output into a trench with large portions results the damages of pipes isolation and emptinesses formation, in consequence  settling and washing of soil. A bulldozer with the screw intensifier (SI, is deprived lacks of an odinary bulldozer  moving along a trench, it moves the loose soil that does not fall on a pipeline, but rolles on it. Thus the circuitous speed of a cutting edge of SI exceeds the speed of the base machine moving that provides the strong soil treatment (before dispersion before output into a trench. Purpose. The algorithm development of the rotational moment determination on the SI driveshaft, the consumable energy, the energy intensity and the working process productivity of the reverse trench refillings depending on physical and mechanical properties of soil, geometrical parameters of SI and bulldozer optimal speed. Conclusion. The developed algorithm allows to define that at the fixed value of the rotational speed the rotational moment and indicated efficiency of SI at the optimum speed increasing of the base machine change on a linear law; the optimum speed change of the base machine practically does not influence on the energy intensity at the considered change of the rotational speed .

  18. The potential to intensify sulforaphane formation in cooked broccoli (Brassica oleracea var. italica) using mustard seeds (Sinapis alba).

    Science.gov (United States)

    Ghawi, Sameer Khalil; Methven, Lisa; Niranjan, Keshavan

    2013-06-01

    Sulforaphane, a naturally occurring cancer chemopreventive, is the hydrolysis product of glucoraphanin, the main glucosinolate in broccoli. The hydrolysis requires myrosinase isoenzyme to be present in sufficient activity; however, processing leads to its denaturation and hence reduced hydrolysis. In this study, the effect of adding mustard seeds, which contain a more resilient isoform of myrosinase, to processed broccoli was investigated with a view to intensify the formation of sulforaphane. Thermal inactivation of myrosinase from both broccoli and mustard seeds was studied. Thermal degradation of broccoli glucoraphanin was investigated in addition to the effects of thermal processing on the formation of sulforaphane and sulforaphane nitrile. Limited thermal degradation of glucoraphanin (less than 12%) was observed when broccoli was placed in vacuum sealed bag (sous vide) and cooked in a water bath at 100°C for 8 and 12 min. Boiling broccoli in water prevented the formation of any significant levels of sulforaphane due to inactivated myrosinase. However, addition of powdered mustard seeds to the heat processed broccoli significantly increased the formation of sulforaphane. Crown Copyright © 2012. Published by Elsevier Ltd. All rights reserved.

  19. Intensifying radiation induced grafting of 4-vinylpyridine/glycidyl methacrylate mixtures onto poly(ethylene-co-tetrafluoroethylene) films using ultrasound

    International Nuclear Information System (INIS)

    Nasef, Mohamed Mahmoud; Sithambaranathan, Paveswari; Ahmad, Arshad; Abouzari-lotf, Ebrahim

    2017-01-01

    A new ultrasound-aided method was used to enhance grafting of 4-vinylpyridine (4-VP) and glycidyl methacrylate (GMA) monomers mixtures onto electron beam (EB) irradiated poly(ethylene-co-tetrafluoroethylene) (ETFE) film for the first time. The effects of reaction parameters such as absorbed dose, monomer concentration, reaction time on both of degree of grafting (DG) and grafting efficiency (GE) were investigated under sonication and conventional grafting at similar temperatures. Fourier transform infrared (FTIR) and atomic force microscopy (AFM) were used to monitor the impact of the applied ultrasound on composition and surfaces of the grafted films whereas 1 H-NMR was used to investigate composition of the grafting residues. The ultrasound-aided grafting of 4-VP/GMA was found to enhance both of DG% and GE remarkably. Moreover, it produced grafted ETFE films having smoother surfaces without homopolymer contamination compared to grafted films obtained from conventional grafting. The results of this study suggest that the use of ultrasound is a promising way for intensifying grafting process and improving its economy. - Highlights: • Grafting of 4-VP/GMA onto ETFE films was carried out with the aid of ultrasound. • Degree of grafting was found to be strongly dependent on reaction parameters. • Sonication remarkably enhanced the reaction kinetics and grafting efficiency. • Grafted films with smoother surfaces without homopolymer contamination were obtained. • Ultrasound aided grafting is superior to conventional one and promotes intensification.

  20. Intensified pharmaceutical care is improving immunosuppressive medication adherence in kidney transplant recipients during the first post-transplant year: a quasi-experimental study.

    Science.gov (United States)

    Joost, Robert; Dörje, Frank; Schwitulla, Judith; Eckardt, Kai-Uwe; Hugo, Christian

    2014-08-01

    Medication adherence is critical for transplant patients because the consequences of non-adherence can result in allograft loss and may be life threatening. A prospective study with 74 renal transplant recipients using a sequential control group design was performed to investigate the impact of a pharmaceutical intensified care programme led by a clinical pharmacist on daily drug adherence during the first year after renal transplantation. Thirty-nine patients of the control group received the already established standardized drug and transplant training, while 35 patients of the intensified care group (ICG) received additional inpatient and outpatient pharmaceutical care and counselling by a dedicated clinical pharmacist. Applied interventions were clustered and classified using the behaviour change technique taxonomy according to Michie. Adherence to immunosuppressive drug therapy was monitored up to 1 year using a medication event monitoring system, pill count (PC), drug holiday (DH) occurrence, Morisky questionnaire and self-report. Sixty-seven patients (35 of the standard care and 32 of the ICG) were analysed. Implementation of DA was significantly (P = 0.014) improved in patients of the ICG (91%) compared with SCG (75%) during the first year after transplantion. Daily adherence measures were already improved within 30-40 days after start of intensified patient care and continued throughout the study period. Intensified care patients also showed significantly better results for taking adherence (P = 0.006), PC (P = 0.008) and DHs (P = 0.001). The additional, intensified pharmaceutical care improved patients' medication adherence remarkably, suggesting that the applied additional care programme has the potential to improve outcomes after organ transplantation. © The Author 2014. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

  1. Deforestation intensifies hot days

    Science.gov (United States)

    Stoy, Paul C.

    2018-05-01

    Deforestation often increases land-surface and near-surface temperatures, but climate models struggle to simulate this effect. Research now shows that deforestation has increased the severity of extreme heat in temperate regions of North America and Europe. This points to opportunities to mitigate extreme heat.

  2. Intensifying the Atmospheric

    DEFF Research Database (Denmark)

    Liebst, Lasse Suonperä

    2012-01-01

    The phenomenological concept of urban atmospheres is more often applied as an aesthetic description of the metropolitan space as such. This conceptualization is supported in this paper; however, I strive to give the concept a post-phenomenological axial turn. While phenomenology, due to its under...... sufficiently intense. All things considered, the paper should be read as a sociological contribution to theoretically reconstruct the concept of urban atmospheres in the light of spatial morphology....

  3. Wastewater treatment in a compact intensified wetland system at the Badboot: a floating swimming pool in Belgium.

    Science.gov (United States)

    Van Oirschot, D; Wallace, S; Van Deun, R

    2015-09-01

    The Badboot (Dutch for swimming pool boat) is a floating swimming pool located in the city center of Antwerp in Belgium. The overall design consists of a recycled ferry boat that serves as a restaurant and next to that a newly built ship that harbours an Olympic size swimming pool, sun decks, locker rooms with showers, and a party space. A major design goal of the project was to make the ship as environmentally friendly as possible. To avoid discharge of contaminated waste water in the Antwerp docks, the ship includes onsite treatment of wastewater in a compact constructed wetland. The treatment wetland system was designed to treat wastewater from visitor locker rooms, showers, toilets, two bars, and the wastewater from the restaurant kitchen. Due to the limited space on board the ship, only 188 m(2) could be allocated to a wetland treatment system. As a result, part of the design included intensification of the wetland treatment process through the use of Forced Bed Aeration, which injects small quantities of air in a very uniform grid pattern throughout the wetland with a mechanical air compressor. The system was monitored between August 2012 and March 2013 (with additional sampling in the autumn of 2014). Flows and loads to the wetland were highly variable, but removal efficiency was extremely high; 99.5 % for chemical oxygen demand (COD), 88.6 % for total nitrogen and 97.2 % for ammonia. The treatment performance was assessed using a first-order, tanks-in-series model (the P-k-C* model) and found to be roughly equivalent to similar intensified wetlands operating in Germany. However, treatment performance was substantially better than data reported on passive wetlands, likely as a result of intensification. Even with mechanically assisted aeration, the total oxygen delivered to the treatment wetlands was insufficient to support conventional nitrification and denitrification, so it is likely that alternate nitrogen removal pathways, such as anammox, are

  4. Short-term Risk of Serious Fall Injuries in Older Adults Initiating and Intensifying Treatment with Antihypertensive Medication

    Science.gov (United States)

    Shimbo, Daichi; Bowling, C. Barrett; Levitan, Emily B.; Deng, Luqin; Sim, John J.; Huang, Lei; Reynolds, Kristi; Muntner, Paul

    2016-01-01

    Background Antihypertensive medication use has been associated with an increased risk of falls in some but not all studies. Few data are available on the short-term risk of falls following antihypertensive medication initiation and intensification. Methods and Results We examined the association between initiating and intensifying antihypertensive medication and serious fall injuries in a case-crossover study of 90,127 Medicare beneficiaries who were ≥65 years old and had a serious fall injury between July 1, 2007 and December 31, 2012, based on emergency department and inpatient claims. Antihypertensive medication initiation was defined by a prescription fill with no fills in the prior year. Intensification was defined by the addition of a new antihypertensive class, and, separately, titration by the addition of a new class or increase in dosage of a current class. Exposures were ascertained for the 15 days before the fall (case period) and six 15-day earlier periods (control periods). Overall, 272, 1508, and 3113 Medicare beneficiaries initiated, added a new class of antihypertensive medication or titrated therapy, respectively, within 15 days of their serious fall injury. The odds for a serious fall injury was increased during the 15 days following antihypertensive medication initiation [odds ratio, OR, 1.36 (95% CI 1.19, 1.55)], adding a new class [OR 1.16 (95% CI 1.10, 1.23)], and titration [OR 1.13 (95% CI 1.08, 1.18)]. These associations were attenuated beyond 15 days. Conclusions Antihypertensive medication initiation and intensification was associated with a short-term, but not long-term, increased risk of serious fall injuries among older adults. PMID:27166208

  5. Seismo-Ionospheric Coupling as Intensified EIA Observed by Satellite Electron Density and GPS-TEC Data

    Science.gov (United States)

    Ryu, K.; Jangsoo, C.; Kim, S. G.; Jeong, K. S.; Parrot, M.; Pulinets, S. A.; Oyama, K. I.

    2014-12-01

    Examples of intensified EIA features temporally and spatially related to large earthquakes observed by satellites and GPS-TEC are introduced. The precursory, concurrent, and ex-post enhancements of EIA represented by the equatorial electron density, which are thought to be related to the M8.7 Northern Sumatra earthquake of March 2005, the M8.0 Pisco earthquake of August 2007, and the M7.9 Wenchuan Earthquake of 12 May 2008, are shown with space weather condition. Based on the case studies, statistical analysis on the ionospheric electron density data measured by the Detection of Electro-Magnetic Emissions Transmitted from Earthquake Regions satellite (DEMETER) over a period of 2005-2010 was executed in order to investigate the correlation between seismic activity and equatorial plasma density variations. To simplify the analysis, three equatorial regions with frequent earthquakes were selected and then one-dimensional time series analysis between the daily seismic activity indices and the EIA intensity indices were performed for each region with excluding the possible effects from the geomagnetic and solar activity. The statistically significant values of the lagged cross-correlation function, particularly in the region with minimal effects of longitudinal asymmetry, indicate that some of the very large earthquakes with M > 7.0 in the low latitude region can accompany observable seismo-ionospheric coupling phenomena in the form of EIA enhancements, even though the seismic activity is not the most significant driver of the equatorial ionospheric evolution. The physical mechanisms of the seismo-ionospheric coupling to explain the observation and the possibility of earthquake prediction using the EIA intensity variation are discussed.

  6. A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model.

    Directory of Open Access Journals (Sweden)

    Iart Luca Shytaj

    Full Text Available Stably suppressed viremia during ART is essential for establishing reliable simian models for HIV/AIDS. We tested the efficacy of a multidrug ART (highly intensified ART in a wide range of viremic conditions (10³-10⁷ viral RNA copies/mL in SIVmac251-infected rhesus macaques, and its impact on the viral reservoir. Eleven macaques in the pre-AIDS stage of the disease were treated with a multidrug combination (highly intensified ART consisting of two nucleosidic/nucleotidic reverse transcriptase inhibitors (emtricitabine and tenofovir, an integrase inhibitor (raltegravir, a protease inhibitor (ritonavir-boosted darunavir and the CCR5 blocker maraviroc. All animals stably displayed viral loads below the limit of detection of the assay (i.e. <40 RNA copies/mL after starting highly intensified ART. By increasing the sensitivity of the assay to 3 RNA copies/mL, viral load was still below the limit of detection in all subjects tested. Importantly, viral DNA resulted below the assay detection limit (<2 copies of DNA/5*10⁵ cells in PBMCs and rectal biopsies of all animals at the end of the follow-up, and in lymph node biopsies from the majority of the study subjects. Moreover, highly intensified ART decreased central/transitional memory, effector memory and activated (HLA-DR⁺ effector memory CD4⁺ T-cells in vivo, in line with the role of these subsets as the main cell subpopulations harbouring the virus. Finally, treatment with highly intensified ART at viral load rebound following suspension of a previous anti-reservoir therapy eventually improved the spontaneous containment of viral load following suspension of the second therapeutic cycle, thus leading to a persistent suppression of viremia in the absence of ART. In conclusion, we show, for the first time, complete suppression of viral load by highly intensified ART and a likely associated restriction of the viral reservoir in the macaque AIDS model, making it a useful platform for testing

  7. A comparative study about the efficiency of several industrial radiographic intensifying screens types by evaluation factor and the equivalent penetrometer sensitivity

    International Nuclear Information System (INIS)

    Ramos, C.W.; Gante, V.; Ribeiro, L.M.

    1992-05-01

    When a x-ray or gamma-ray beam strikes a film usually less than 1% of the energy is absorbed resulting in a photographic effect. Obviously, any mean of utilizing more fully the unabsorbed percentage of energy without complicating too much the technical radiographic procedure is highly desirable. One very common procedure is to use the film between two intensifying screens. These screens have the property of emitting electrons (lead screens) or become fluorescent (fluorescent screens) when stricken by electromagnetic radiation thus resulting in a supplementary photographic action on the film emulsion. This work presents an efficiency comparison of the more usual varieties of these intensifying screens for energies of x-ray until 300 K V. (author)

  8. Clinical inertia in poorly controlled elderly hypertensive patients: a cross-sectional study in Spanish physicians to ascertain reasons for not intensifying treatment.

    Science.gov (United States)

    Gil-Guillén, Vicente; Orozco-Beltrán, Domingo; Carratalá-Munuera, Concepción; Márquez-Contreras, Emilio; Durazo-Arvizu, Ramón; Cooper, Richard; Pertusa-Martínez, Salvador; Pita-Fernandez, Salvador; González-Segura, Diego; Martin-de-Pablo, José Luis; Pallarés, Vicente; Fernández, Antonio; Redón, Josep

    2013-06-01

    Clinical inertia, the failure of physicians to initiate or intensify therapy when indicated, is a major problem in the management of hypertension and may be more prevalent in elderly patients. Overcoming clinical inertia requires understanding its causes and evaluating certain factors, particularly those related to physicians. The objective of our study was to determine the rate of clinical inertia and the physician-reported reasons for it. An observational, cross-sectional, multi-center study was carried out in a primary care setting. We included 512 physicians, with a consecutive sampling of 1,499 hypertensive patients with clinical inertia. Clinical inertia was defined when physicians did not modify treatment despite knowing that the therapeutic target had not been reached. Clinical inertia was considered to be justified (JCI) when physicians provided an explanation for not intensifying treatment and as not justified (nJCI) when no reasons were given. JCI was observed in 30.1 % (95 % CI 27.8-32.4) of patients (n = 451) and nJCI in 69.9 % (95 % CI 67.6-72.2) (n = 1,058). JCI was associated with higher blood pressure (BP) values (both systolic and diastolic) and diabetes (p = 0.012) than nJCI. nJCI was associated with patients having an isolated increase of systolic or diastolic or high borderline BP values or cardiovascular disease. Physicians provided reasons for not intensifying treatment in poorly controlled patients in only 30 % of instances. Main reasons for not intensifying treatment were borderline BP values, co-morbidity, suspected white coat effect, or perceived difficulty achieving target. nJCI was associated with high borderline BP values and cardiovascular disease.

  9. Randomized comparison of renal denervation versus intensified pharmacotherapy including spironolactone in true-resistant hypertension: six-month results from the Prague-15 study.

    Science.gov (United States)

    Rosa, Ján; Widimský, Petr; Toušek, Petr; Petrák, Ondřej; Čurila, Karol; Waldauf, Petr; Bednář, František; Zelinka, Tomáš; Holaj, Robert; Štrauch, Branislav; Šomlóová, Zuzana; Táborský, Miloš; Václavík, Jan; Kociánová, Eva; Branny, Marian; Nykl, Igor; Jiravský, Otakar; Widimský, Jiří

    2015-02-01

    This prospective, randomized, open-label multicenter trial evaluated the efficacy of catheter-based renal denervation (Symplicity, Medtronic) versus intensified pharmacological treatment including spironolactone (if tolerated) in patients with true-resistant hypertension. This was confirmed by 24-hour ambulatory blood pressure monitoring after excluding secondary hypertension and confirmation of adherence to therapy by measurement of plasma antihypertensive drug levels before enrollment. One-hundred six patients were randomized to renal denervation (n=52), or intensified pharmacological treatment (n=54) with baseline systolic blood pressure of 159±17 and 155±17 mm Hg and average number of drugs 5.1 and 5.4, respectively. A significant reduction in 24-hour average systolic blood pressure after 6 months (-8.6 [95% cofidence interval: -11.8, -5.3] mm Hg; Pblood pressure (-12.4 [95% cofidence interval: -17.0, -7.8] mm Hg; Pblood pressure comparable with intensified pharmacotherapy. © 2014 American Heart Association, Inc.

  10. virtX - a computer based system for training the intrasurgical use of mobile image intensifier systems

    Directory of Open Access Journals (Sweden)

    Pretschner, Dietrich Peter

    2006-11-01

    Full Text Available Background and objectives: Currently the correct intrasurgical positioning and adjustment of mobile X-ray image intensifiers (C-arm can be learned theoretically through the use of textbooks, the practical training with the device itself suffers from the lack of visual feedback, i.e. radiographs corresponding to the adjustment of the C-arm. This leads to the question, whether the training of correct operation and adjustment of a C-arm in different operation scenarios can be supported by a C-arm simulation system being part of a CBT system (Computer Based Training. Methods: In co-operation with physicians from accident surgery and radiology the computer-based training system virtX was developed. virtX confronts the user with different exercises of C-arm adjustment and evaluates their execution and the results. These tasks can be created with the help of an authoring tool and can be accomplished by the trainee in different modes: a pure virtual mode and a combined virtual-real mode. In the pure virtual mode the user controls the virtual C-arm in a virtual operating theatre via the graphic-interactive virtX user interface. In the virtual-real mode however the position and orientation of a real C-arm are detected and mapped onto the virtual C-arm. At any time during the completion of an exercise the user can produce a close-to-reality, virtual radiograph and can control all parameters, like the positions of the apertures, X-ray intensity, etc. virtX was used on a three-day course for OR personnel with 120 participants and evaluated using questionnaires.Results: 79 of the participants returned a questionnaire. The average age of the 62 female and 15 male participants (two n.s. was 34 ± 9 years, their professional experience was 8.3 ± 7.6 years. 18 persons (23% indicated to work occasionally with a C-arm, 61 (77% worked regularly with it. Over 83% of the interviewed participants considered virtX a useful addition to the conventional C-arm training

  11. Intensified Separation of Steviol Glycosides from a Crude Aqueous Extract of Stevia rebaudiana Leaves Using Centrifugal Partition Chromatography.

    Science.gov (United States)

    Hubert, Jane; Borie, Nicolas; Chollet, Sébastien; Perret, Joël; Barbet-Massin, Claire; Berger, Monique; Daydé, Jean; Renault, Jean-Hugues

    2015-11-01

    Aqueous extracts of Stevia rebaudiana leaves have been approved since 2008 by the Joint Expert Committee for Food Additives as sugar substitutes in many food and beverages in Western and Far East Asian countries. The compounds responsible for the natural sweetness of Stevia leaves include a diversity of diterpenoid glycosides derived from a steviol skeleton. These steviol glycosides also exhibit a low calorific value as well as promising therapeutic applications, particularly for the treatment of sugar metabolism disturbances. In this work, centrifugal partition chromatography is proposed as an efficient technical alternative to purify steviol glycosides from crude aqueous extracts of Stevia leaves on a multigram scale. Two different commercial instruments, including an ASCPC250® and a FCPE300® made of columns containing 1890 and 231 twin-cells, respectively, were evaluated and compared. All experiments were performed with a polar biphasic solvent system composed of ethyl acetate, n-butanol, and water in a gradient elution mode. When using the 1890 partition cell centrifugal partition chromatography column of 250 mL, 42 mg of stevioside, 68 mg of dulcoside A, and 172 mg of rebaudioside A, three major constituents of the initial extract were obtained from 1 g of the initial mixture at purities of 81%, 83%, and 99%, respectively. The productivity was further improved by intensifying the procedure on the 231 partition cell centrifugal partition chromatography column of 303 mL with the sample mass loading increased up to 5 g, resulting in the recovery of 1.2 g of stevioside, 100 mg of dulcoside A, and 1.1 g of rebaudioside A at purities of 79%, 62%, and 98%, respectively. The structures of the isolated compounds were validated by HPLC-UV, ESI-MS, (1)H, and (13)C NMR analyses. Altogether, the results demonstrate that the column design (i.e., the partition cell number) is an important aspect to be considered for a larger scale centrifugal partition chromatography

  12. Cognitive Therapy and Task Concentration Training Applied as Intensified Group Therapies for Social Anxiety Disorder with Fear of Blushing-A Randomized Controlled Trial.

    Science.gov (United States)

    Härtling, Samia; Klotsche, Jens; Heinrich, Anke; Hoyer, Jürgen

    2016-11-01

    The current study examines the efficacy of intensified group therapy for social anxiety disorder with fear of blushing. Task concentration training (TCT) and cognitive therapy (CT) were applied during one weekend and compared with a waiting list condition in a randomized controlled trial including 82 patients. On a second weekend, another intervention was added (resulting in TCT-CT and CT-TCT sequences) to examine order effects. Task concentration training and CT were both superior to the waiting list and equally effective after the first therapy weekend. Also, no differences were found between the sequences TCT-CT and CT-TCT at post-assessment. At 6- and 12-month follow-up, effects remained stable or further improved. At the 6-month follow-up, remission rates in completers, established by diagnostic status, were between 69% and 73%. Intensified group therapy is highly effective in treating social anxiety disorder with fear of blushing. Group formats for patients sharing a common primary concern may contribute to the dissemination of cognitive-behavioural therapy. Copyright © 2015 John Wiley & Sons, Ltd. Key Practitioner Message: This study focuses on blushing from fearful individuals within the SAD spectrum to improve evidence for treatment efficacy in those whose social fears are centred around observable bodily sensations. This study integrates task concentration training into the SAD model of Clark and Wells to combine two evidence-based treatments for SAD under one treatment model. This study uses an innovative format of brief, intensified group therapy, conducted on two full-day weekend group sessions delivered over two weekends, with strong observed effect sizes. Copyright © 2015 John Wiley & Sons, Ltd.

  13. Cost-effectiveness of intensified versus conventional multifactorial intervention in type 2 diabetes: results and projections from the Steno-2 study

    DEFF Research Database (Denmark)

    Gaede, Peter; Valentine, William J; Palmer, Andrew J

    2008-01-01

    and account Danish-specific costs to project life expectancy, quality-adjusted life expectancy (QALE), and lifetime direct medical costs expressed in year 2005 Euros. Clinical and cost outcomes were projected over patient lifetimes and discounted at 3% annually. Sensitivity analyses were performed. RESULTS...... gained. This is considered a conservative estimate because accounting prescription of generic drugs and capturing indirect costs would further favor intensified therapy. CONCLUSIONS: From a health care payer perspective in Denmark, intensive therapy was more cost-effective than conventional treatment...

  14. Study of two novel large-field-of-view image intensifiers versus conventional chest radiography with use of FROC methods and simulated pulmonary nodules

    International Nuclear Information System (INIS)

    Winter, L.H.L.; Chakraborty, D.P.; Van Waes, P.F.G.M.; Puylaert, C.B.A.J.

    1989-01-01

    Two novel large-field-of-view image intensifier (LFOV 1.1) tubes have been introduced whose image area makes them suitable for chest imaging. Both modalities present a 100-mm hard-copy image to the radiologist. A pulmonary nodule performance experiment was done to compare the diagnostic accuracy of these tubes with conventional full-size chest images. The data were analyzed with the maximum-likelihood FROCFIT program. The relative ranking in terms of decreasing A1 values was TLX, Siemens 43-cm mode, conventional radiography, and Siemens 57-cm mode

  15. Differences of X-ray exposure between X-ray diagnostics with a conventional X-ray screen-system and with an image-intensifier-television-unit

    International Nuclear Information System (INIS)

    Loehr, H.; Vogel, H.; Reinhart, J.; Jantzen, R.

    1977-01-01

    During X-ray diagnostics of patients in the II. Medizinische Poliklinik the X-ray exposure was determined. It corresponded to the data described in literature. Two groups were compared: 518 patients examined with a conventional X-ray screen-system and 642 patients examined with an image-intensifier-television-system. The results demonstrated that with exception of thoracical X-ray examination the replacing of the old system by the television system brought a remarkable increase of the X-ray exposure. The doses depended of the patients constitution to a high degree. (orig.) [de

  16. Evaluation of a program to improve diabetes care through intensified care management activities and diabetes medication copayment reduction.

    Science.gov (United States)

    Kogut, Stephen J; Johnson, Scott; Higgins, Tara; Quilliam, Brian

    2012-05-01

    Medication copayment reduction can be integrated with disease management programs to incentivize patient engagement in chronic care management. While disease management programs in diabetes have been evaluated across a range of settings and designs, less is known regarding the effectiveness of copayment reduction as a component of disease management. To evaluate the short-term results of a diabetes-focused disease management program that included copayment reduction, care coordination, and patient goal setting, focusing on rates of evidence-based care processes and all-cause pharmacy and health care costs. Blue Cross Blue Shield of Rhode Island offered large employer groups the opportunity to participate in a diabetes disease management initiative that featured reduced copayments (from $7/$25/$40 for generic, tier 2, and tier 3 drugs, respectively, to $0 for generic and $0-$2 for brand drugs) for diabetes-related medications. In return for the copayment reduction, participants agreed to the following: (a) participate in care coordination with a case manager, (b) have an annual physical examination, (c) have a hemoglobin A1c blood test at least twice annually, and (d) have a low-density lipoprotein cholesterol (LDL-C) test at least once annually. Patients received personalized support provided by a registered nurse and dietician, disease-related education provided by nurses, and intensified case management services, including working with a health coach to establish healthy behavioral change goals. All study subjects were aged 18 years or older and had at least 1 ICD-9-CM code for diabetes and at least 1 claim for an antidiabetic drug during a 12-month measurement period, which was each subject's most recent 12-month period of continuous enrollment from January 1, 2008, through May 31, 2010. Administrative claims data were used to determine the percentage of intervention (participating) and nonintervention (nonparticipating) subjects from among all of the plan

  17. Process for increasing the capacity and/or energetic efficiency of pressure-intensifying stations of petroleum and natural gas pipelines

    Energy Technology Data Exchange (ETDEWEB)

    Belcsak, Z.; Luptak, E.; Palfalvi, G.; Vadas, Z.; Vasvari, V.; Wenzel, B.

    1982-03-30

    The invention is used in the field of pressure-intensifying stations of natural gas and oil pipelines. The essential character of the process according to the invention is that steam is produced in a boiler heated with the outgoing flue gas of a gas turbine driving the compressor. The steam is conducted into the steam turbine for futher driving the compressor. The main feature of the equipment according to the invention is that the ratio of the simultaneously operating gas turbines and steam turbines may vary from the equivalent to triple value, the ratio is suitably double, and the stand-by machine unit is driven always by gas turbine, separate flue gas boiler is connected to each of the gas turbines, while the boilers are equipped with supplementary and/or substituting automatic heater. Advantages of the invention are that it: reduces the self-consumption by about 1/3 rd, and improves the safety of the pressure-intensification realizable in existing pressure-intensifying stations.

  18. Gonad doses for male patients from stomach examination and oral cholegraphy using the X-ray image intensifying technique and television fluoroscopy

    International Nuclear Information System (INIS)

    Steinbach, W.; Richter, K.; Koenig, W.; Menzel, B.; Reisinger, W.; Uhlich, F.

    1979-01-01

    The gonad dose was measured for male patients undergoing stomach examinations and oral cholegraphy by means of a diagnostic twelve pulse generator (TuR D 1500) and an X-ray apparatus 'Diagnost 100' (Philips-Mueller). In a small group of patients the gonad dose was ascertained per exposure to a 70 mm single spot film, to a 24 cm x 30 cm full size radiograph, and per minute of exposure to image intensifier fluoroscopy. The total gonad dose in both the diagnostic techniques was determined seperately in larger groups of patients. In stomach examination large size radiography led to a gonad dose 20 times higher than that obtained with the spot film technique, while exposure from cholegraphy was 10 times higher. The gonad dose per exposure of a single spot film was about 0.5 mrad. In examinations of the stomach the gonad dose from one minute fluroscopy was 18 times higher than the doses determined for a single spot film, and in cholegraphy it was 10 times higher. Supposing mean values of the number of radiographs and of the fluoroscopy time according to the conditions applied, the gonad dose in stomach examination from the film-screen technique is about twice that from the television image-intensifying technique. By comparison, oral cholegraphy exclusively performed by large-size radiography yielded about the same gonad dose as the spot film television technique. Total dose values determined separately confirmed these evaluations. (author)

  19. Comparison of vessel contrast measured with a scanning-beam digital x-ray system and an image intensifier/television system

    International Nuclear Information System (INIS)

    Speidel, Michael A.; Wilfley, Brian P.; Heanue, Joseph A.; Betts, Timothy D.; Van Lysel, Michael S.

    2001-01-01

    Vessel contrast was measured in the fluoroscopic images produced by a scanning-beam digital x-ray (SBDX) system and an image intensifier/television (II/TV) based system. The SBDX system electronically scans a series of pencil x-ray beams across the patient, each of which is directed at a distant small-area detector array. The reduction in detected scatter achieved with this geometry was expected to provide an increase in image contrast. Vessel contrast was evaluated from images of a phantom containing iodinated tubes. The vessels were inserted into an acrylic stack to provide a patient-mimicking scattering medium. Vessel diameter ranged from 0.3 to 3.1 mm. Images were acquired at 100 kVp with the SBDX and II/TV systems and averaged to reduce x-ray noise. The II/TV system was operated in the 6-in. image intensifier mode with an anti-scatter grid. The increase in contrast in the SBDX images, expressed as a ratio of the measured SBDX and II/TV contrasts, ranged from 1.63 to 1.79 for individual vessels. This agreed well with a prediction of the contrast improvement ratio for this experiment, based on measurements of the scatter fraction, object-plane line spread functions, and consideration of the source spectrum and detector absorption properties. The predicted contrast improvement ratio for SBDX relative to II/TV images was 1.62 to 1.77

  20. Numerical investigations on the effect of the axial interval between intensifying spacer grids on the critical heat flux value for fuel assemblies with non-uniform axial power distribution

    International Nuclear Information System (INIS)

    Kireeva, D.; Oleksyuk, D.

    2015-01-01

    In this paper a number of numerical studies on intensifying heat exchange conducted by NRC 'Kurchatov Institute' are presented. A standardised heat exchange intensifying spacer grid (UDRI) can be installed at any height along the fuel assembly (FA) heat-generating section. When installed at the bottom of a fuel assembly, the UDRI facilitates intensive coolant mixing; the UDRI mounted at the top of a FA provides better mixing and the enhancement in heat exchange. The application of the heat exchange intensifying spacer grids results in better flattening of the coolant parameters along the cross-section and higher critical heat flux ratio. The investigations were carried out by means of numerical code SC-INT using mesh generation that have been specially designed by NRC 'Kurchatov Institute' to perform calculations for fuel assemblies equipped with the intensifying spacer grids. The effect of the axial interval between UDRI grids on the critical heat flux value for two typical axial power shapes has been investigated. The derived optimal solutions for the positioning of intensifying grids are also presented

  1. Projecting of wave height and water level on reef-lined coasts due to intensified tropical cyclones and sea level rise in Palau to 2100

    Directory of Open Access Journals (Sweden)

    C. Hongo

    2018-03-01

    Full Text Available Tropical cyclones (TCs and sea level rise (SLR cause major problems including beach erosion, saltwater intrusion into groundwater, and damage to infrastructure in coastal areas. The magnitude and extent of damage is predicted to increase as a consequence of future climate change and local factors. Upward reef growth has attracted attention for its role as a natural breakwater, reducing the risks of natural disasters to coastal communities. However, projections of change in the risk to coastal reefs under conditions of intensified TCs and SLR are poorly quantified. In this study we projected the wave height and water level on Melekeok reef in the Palau Islands by 2100, based on wave simulations under intensified TCs (significant wave height at the outer ocean: SWHo = 8.7–11.0 m; significant wave period at the outer ocean: SWPo = 13–15 s and SLR (0.24–0.98 m. To understand effects of upward reef growth on the reduction of the wave height and water level, the simulation was conducted for two reef condition scenarios: a degraded reef and a healthy reef. Moreover, analyses of reef growth based on a drilled core provided an assessment of the coral community and rate of reef production necessary to reduce the risk from TCs and SLR on the coastal areas. According to our calculations under intensified TCs and SLR by 2100, significant wave heights at the reef flat (SWHr will increase from 1.05–1.24 m at present to 2.14 m if reefs are degraded. Similarly, by 2100 the water level at the shoreline (WLs will increase from 0.86–2.10 m at present to 1.19–3.45 m if reefs are degraded. These predicted changes will probably cause beach erosion, saltwater intrusion into groundwater, and damage to infrastructure, because the coastal village is located at  ∼ 3 m above the present mean sea level. These findings imply that even if the SWHr is decreased by only 0.1 m by upward reef growth, it will probably reduce the risks of

  2. Effect of 2-wk intensified training and inactivity on muscle Na+-K+ pump expression, phospholemman (FXYD1) phosphorylation, and performance in soccer players.

    Science.gov (United States)

    Thomassen, Martin; Christensen, Peter M; Gunnarsson, Thomas P; Nybo, Lars; Bangsbo, Jens

    2010-04-01

    The present study examined muscle adaptations and alterations in performance of highly trained soccer players with intensified training or training cessation. Eighteen elite soccer players were, for a 2-wk period, assigned to either a group that performed high-intensity training with a reduction in the amount of training (HI, n = 7), or an inactivity group without training (IN, n = 11). HI improved (P Na(+)-K(+) pump alpha(2)-isoform was 15% higher (P Na(+)-K(+) pump expression was not changed. In HI, the FXYD1ser68-to-FXYD1 ratio was 27% higher (P Na(+)-K(+) pump alpha(2)-isoform expression, and that cessation of training for 2 wk does not affect the expression of Na(+)-K(+) pump isoforms. Resting phosphorylation status of the Na(+)-K(+) pump is changed by training and inactivity and may play a role in performance during repeated, intense exercise.

  3. Projecting of wave height and water level on reef-lined coasts due to intensified tropical cyclones and sea level rise in Palau to 2100

    Science.gov (United States)

    Hongo, Chuki; Kurihara, Haruko; Golbuu, Yimnang

    2018-03-01

    Tropical cyclones (TCs) and sea level rise (SLR) cause major problems including beach erosion, saltwater intrusion into groundwater, and damage to infrastructure in coastal areas. The magnitude and extent of damage is predicted to increase as a consequence of future climate change and local factors. Upward reef growth has attracted attention for its role as a natural breakwater, reducing the risks of natural disasters to coastal communities. However, projections of change in the risk to coastal reefs under conditions of intensified TCs and SLR are poorly quantified. In this study we projected the wave height and water level on Melekeok reef in the Palau Islands by 2100, based on wave simulations under intensified TCs (significant wave height at the outer ocean: SWHo = 8.7-11.0 m; significant wave period at the outer ocean: SWPo = 13-15 s) and SLR (0.24-0.98 m). To understand effects of upward reef growth on the reduction of the wave height and water level, the simulation was conducted for two reef condition scenarios: a degraded reef and a healthy reef. Moreover, analyses of reef growth based on a drilled core provided an assessment of the coral community and rate of reef production necessary to reduce the risk from TCs and SLR on the coastal areas. According to our calculations under intensified TCs and SLR by 2100, significant wave heights at the reef flat (SWHr) will increase from 1.05-1.24 m at present to 2.14 m if reefs are degraded. Similarly, by 2100 the water level at the shoreline (WLs) will increase from 0.86-2.10 m at present to 1.19-3.45 m if reefs are degraded. These predicted changes will probably cause beach erosion, saltwater intrusion into groundwater, and damage to infrastructure, because the coastal village is located at ˜ 3 m above the present mean sea level. These findings imply that even if the SWHr is decreased by only 0.1 m by upward reef growth, it will probably reduce the risks of costal damages. Our results showed that a healthy reef

  4. Intensified secondary prevention intending a reduction of recurrent events in TIA and minor stroke patients (INSPiRE-TMS: a protocol for a randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Leistner Stefanie

    2013-01-01

    Full Text Available Abstract Background Patients with recent stroke or TIA are at high risk for new vascular events. Several evidence based strategies in secondary prevention of stroke are available but frequently underused. Support programs with multifactorial risk factor modifications after stroke or TIA have not been investigated in large-scale prospective controlled trials so far. INSPiRE-TMS is a prospective, multi-center, randomized open intervention trial for intensified secondary prevention after minor stroke and TIA. Methods/design Patients with acute TIA or minor stroke admitted to the participating stroke centers are screened and recruited during in-hospital stay. Patients are randomised in a 1:1 ratio to intervention (support program and control (usual care arms. Inclusion of 2.082 patients is planned. The support program includes cardiovascular risk factor measurement and feedback, monitoring of medication adherence, coaching in lifestyle modifications, and active involvement of relatives. Standardized motivational interviewing is used to assess and enhance patients’ motivation. Primary objective is a reduction of new major vascular events defined as nonfatal stroke and myocardial infarction or vascular death. Recruitment time is planned for 3.5 years, follow up time is at least 2 years for every patient resulting in a total study time of 5 years (first patient in to last patient out. Discussion Given the high risk for vascular re-events in acute stroke and the available effective strategies in secondary prevention, the INSPIRE-TMS support program has the potential to lead to a relevant reduction of recurrent events and a prolongation of the event-free survival time. The trial will provide the basis for the decision whether an intensified secondary prevention program after stroke should be implemented into regular care. A cost-effectiveness evaluation will be performed. Trial registration clinicaltrials.gov: 01586702

  5. The role of oxidative, inflammatory and neuroendocrinological systems during exercise stress in athletes: implications of antioxidant supplementation on physiological adaptation during intensified physical training.

    Science.gov (United States)

    Slattery, Katie; Bentley, David; Coutts, Aaron J

    2015-04-01

    During periods of intensified physical training, reactive oxygen species (ROS) release may exceed the protective capacity of the antioxidant system and lead to dysregulation within the inflammatory and neuroendocrinological systems. Consequently, the efficacy of exogenous antioxidant supplementation to maintain the oxidative balance in states of exercise stress has been widely investigated. The aim of this review was to (1) collate the findings of prior research on the effect of intensive physical training on oxidant-antioxidant balance; (2) summarise the influence of antioxidant supplementation on the reduction-oxidation signalling pathways involved in physiological adaptation; and (3) provide a synopsis on the interactions between the oxidative, inflammatory and neuroendocrinological response to exercise stimuli. Based on prior research, it is evident that ROS are an underlying aetiology in the adaptive process; however, the impact of antioxidant supplementation on physiological adaptation remains unclear. Equivocal results have been reported on the impact of antioxidant supplementation on exercise-induced gene expression. Further research is required to establish whether the interference of antioxidant supplementation consistently observed in animal-based and in vivo research extends to a practical sports setting. Moreover, the varied results reported within the literature may be due to the hormetic response of oxidative, inflammatory and neuroendocrinological systems to an exercise stimulus. The collective findings suggest that intensified physical training places substantial stress on the body, which can manifest as an adaptive or maladaptive physiological response. Additional research is required to determine the efficacy of antioxidant supplementation to minimise exercise-stress during intensive training and promote an adaptive state.

  6. Counter-Memory, Heterochronia, and “History Painting” (After Géricault: Dierk Schmidt’s SIEV-X—On a Case of Intensified Refugee Politics

    Directory of Open Access Journals (Sweden)

    Veronica Tello

    2014-06-01

    Full Text Available This essay examines the disruption of linear time in experimental forms of “history painting” as represented by Dierk Schmidt’s SIEV-X—On a Case of Intensified Refugee Politics (2001-2005. It analyses how the aesthetics of heterochronoia—multiple temporalities—play a crucial role in the development of a new understanding of the politics of “history painting.” As Schmidt’s work reveals, a radical conception of history exists outside the “singular moment,” and in dialogue with heterogenous visual cultures (news media, art history, advertising. In attempting to understand the import of Schmidt’s work, this essay considers his methodologies for creating a heterochronous mode of history painting, particularly his anachronistic engagement with the work of Theodore Géricault and the iconic history painting, The Raft of the Medusa. Unlike previous critical responses to Schmidt’s work, this paper argues that (after Géricault the artist’s use of investigative “journalistic” methodologies for SIEV-X—On a Case of Intensified Refugee Politics do not generate an aesthetics of exposé but rather an aesthetics of “fictionalization.” This aesthetic is defined by the recalibration of documentary and speculative data as a means to reconceive the landscape of the perceptual. The findings of this research demonstrate that the use of disparate fragments—or data—to visualize otherwise diminishing historical events underpins contemporary history painting’s capacity for advancing a distinct economy of affect that circumvents the limitations of the news media and its “monopoly on reality.”

  7. Recent Intensified Winter Coldness in the Mid-High Latitudes of Eurasia and Its Relationship with Daily Extreme Low Temperature Variability

    Directory of Open Access Journals (Sweden)

    Chuhan Lu

    2016-01-01

    Full Text Available Observational records in recent decades show a large-scale decrease in the cold-season temperature variance in the Northern Hemisphere midlatitudes under continuous global warming. However, severe low temperature events in winter frequently occurred in midlatitude Eurasia (MEA in the last decade. Here, we define a new coldness intensity (CI index for the near-surface based on the amplitude of daily anomalously cold temperatures in winter to demonstrate the CI of the variability of low temperature extremes. The results show that a sign-consistent mode dominates the CI variation in MEA, with a marked intensification during the last decade via empirical orthogonal function (EOF analysis. This leading mode is significantly related to the frequency of winter extreme events. The associated circulations are characterized by a remarkable anomalous anticyclone in Northwest Eurasia, which induced substantial cold advection in MEA. The widespread intensified CI in MEA is closely linked with strong surface anticyclones and synoptic blocking in the mid-high latitudes (25°E–85°E. Coincidently, positive phase shifts of the first two leading modes of the extratropical circulation, which feature similar blocking-like anomalies in the northwestern Eurasian subarctic, jointly play an important role in the recent frequency of severe winters.

  8. Coping with chaos: unpredictable food supplies intensify torpor use in an arid-zone marsupial, the fat-tailed dunnart ( Sminthopsis crassicaudata)

    Science.gov (United States)

    Munn, Adam J.; Kern, Pippa; McAllan, Bronwyn M.

    2010-06-01

    The severity, duration and amplitude of extreme weather events are forecast to intensify with current climate trends, over both long (e.g. seasonal) and short (e.g. daily) time-scales. As such, the predictability of food supplies for many small endotherms is likely to become increasingly important. Numerous small mammals and birds combat food shortages using torpor, a controlled reduction in metabolic rate and body temperature that helps lower their daily energy requirements. As such, torpor often has been cited as a key feature allowing some small endotherms to survive highly unpredictable climates, such as tropics or dry deserts, but mensurative demonstrations of this are lacking. We have shown here that when a small desert marsupial, the fat-tailed dunnart ( Sminthopsis crassicaudata), is offered unpredictable levels of daily food, they increase frequency of daily torpor and length of bouts compared with animals offered ad libitum food, but this was not found for animals offered a 70% food-restricted diet. Our data suggest that simple food restriction may not be sufficient for evaluating the efficacy of torpor as a strategy for managing unpredictable climates.

  9. The weighted average cost of capital over the lifecycle of the firm: Is the overinvestment problem of mature firms intensified by a higher WACC?

    Directory of Open Access Journals (Sweden)

    Carlos S. Garcia

    2016-08-01

    Full Text Available Firm lifecycle theory predicts that the Weighted Average Cost of Capital (WACC will tend to fall over the lifecycle of the firm (Mueller, 2003, p. 80-81. However, given that previous research finds that corporate governance deteriorates as firms get older (Mueller and Yun, 1998; Saravia, 2014 there is good reason to suspect that the opposite could be the case, that is, that the WACC is higher for older firms. Since our literature review indicates that no direct tests to clarify this question have been carried out up till now, this paper aims to fill the gap by testing this prediction empirically. Our findings support the proposition that the WACC of younger firms is higher than that of mature firms. Thus, we find that the mature firm overinvestment problem is not intensified by a higher cost of capital, on the contrary, our results suggest that mature firms manage to invest in negative net present value projects even though they have access to cheaper capital. This finding sheds new light on the magnitude of the corporate governance problems found in mature firms.

  10. Development of natural cellulase inhibitor mediated intensified biological pretreatment technology using Pleurotus florida for maximum recovery of cellulose from paddy straw under solid state condition.

    Science.gov (United States)

    Naresh Kumar, Manickam; Ravikumar, Rajarathinam; Thenmozhi, Senniyappan; Kirupa Sankar, Muthuvelu

    2017-11-01

    Inhibitor mediated intensified bio-pretreatment (IMBP) technology using natural cellulase inhibitor (NCI) for maximum cellulose recovery from paddy straw was studied. Pretreatment was carried out under solid state condition. Supplementation of 8% NCI in pretreatment medium improves cellulose recovery and delignification by 1.2 and 1.5-fold respectively, compared to conventional bio-pretreatment due to inhibition of 61% of cellulase activity in IMBP. Further increase in NCI concentration showed negative effect on Pleurotus florida growth and suppress the laccase productivity by 1.1-fold. Laccase activity in IMBP was found to be 2.0U/mL on 19 th day, which is higher than (1.5U/mL) conventional bio-pretreatment. Physico-chemical modifications in paddy straw before and after pretreatment were analysed by SEM, ATR-FTIR, XRD and TGA. According to these findings, the IMBP technology can be a viable eco-friendly technology for sustainable production of bioethanol with maximum cellulose recovery. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Cognitive and pragmatic potential of intensity category means through the process of metaphorization (on the material of intensifiers in Spanish and Russian

    Directory of Open Access Journals (Sweden)

    Karpovskaya Natalya Valerievna

    2015-09-01

    Full Text Available The article deals with the interaction of processes and intensification of metaphor. Intensifiers are understood as lexemes that not only indicate a feature, but also implicitly contain in its meaning this intensity that indicates the degree of manifestation of feature/quality. They are widely used as components of phraseological units and comparative structure that contribute to the realization in the speech stylistic and assessment functions, as well as the embodiment of a pragmatic setting of the author. However, as the translation to the transformation of the subjective factor influences cultural features of national mentality, they often lead to changes in the degree of expressive feature, and hence a change in cognitive-pragmatic potential linguistic unit. Within the category of intensity associations occupy a special place that are activated in metaphor and contribute not only to a more “tangible” comprehension of reality, but also further semantic development of language units and enhancing their cognitive and pragmatic potential, under which we mean the possibility of actualization in speech not only categorical values i nherent in the language units as elements of the language system and language picture of the world, but the implicatures that can occur in interaction with verbal language environment, thereby contributing to the formation of certain perception, understanding and knowledge of reality, as well as the achievement of certain pragmatic effect.

  12. Intensified CCD for ultrafast diagnostics

    International Nuclear Information System (INIS)

    Cheng, J.; Tripp, G.; Coleman, L.

    1978-01-01

    Many of the present laser fusion diagnostics are recorded on either ultrafast streak cameras or on oscilloscopes. For those experiments in which a large volume of data is accumulated, direct computer processing of the information becomes important. We describe an approach which uses a RCA 52501 back-thinned CCD sensor to obtain direct electron readouts for both the streak camera and the CRT. Performance of the 100 GHz streak camera and the 4 GHz CRT are presented. Design parameters and computer interfacing for both systems are described in detail

  13. Atomic war on insects intensified

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1967-06-15

    Intensive research work in many countries using nuclear methods aimed at reducing the immense food losses caused by insects have led to a number of important trial operations this year. Some are now in progress in Capri, the famous Italian tourist island, and in Central America. Both are directed against the Mediterranean fruit fly, which attacks most fruit in tropical and sub-tropical countries. Similar methods are also developing to combat other insect pests

  14. Dark-matter dispute intensifies

    International Nuclear Information System (INIS)

    Avignone, Frank T.

    2000-01-01

    Recent results from a dark-matter experiment in Italy suggest that the elusive weakly interacting massive particle or WIMP has finally been detected - but a rival experimental collaboration in the US disagrees. The controversy surrounding evidence for the discovery of ''dark matter'' particles has heated up following two conflicting talks given at a conference at the end of February. The papers were presented at the 4th International Symposium on Sources and Detection of Dark Matter/Energy in the Universe held in Marina del Ray, California. For almost 70 years astronomers have known that dust, gas and other ordinary matter cannot account for almost 90% of the mass of many galaxies. The galaxies must contain other ''dark'' matter to explain the orbital motions of stars around their centres. Many astrophysicists, cosmologists and particle physicists have conjectured that this seemingly empty space could be populated by a dense body of massive, but very weakly interacting, particles called WIMPs. Such particles would then provide the gravitational fields needed to keep the stars moving as observed. Since the results of the first experimental efforts to detect these particles were published in 1987, literally dozens of experiments have been performed around the world. Two of the most sensitive experiments to date are the DAMA experiment at the Gran Sasso laboratory in Italy, and the CDMS experiment at Stanford University in the US. The DAMA collaboration - which includes physicists from the University of Rome Tor Vergata, the University of Rome La Sapienza and the Chinese Academy in Beijing - has been searching for WIMPs for several years using a large array of sodium-iodide detectors located 1400 m below ground. The CDMS experiment uses cryogenic detectors and is located just 10 m underground. The collaboration includes researchers from several centres in the US and Russia. Assuming that they do exist, a WIMP will occasionally strike a nucleus in the detector material head-on and cause an elastic recoil. The recoil energy depends on the mass and velocity of the WIMP, together with the mass of the target nucleus. This energy can be measured in several ways, depending on the detector used. A scintillation photon may be emitted, electric charge may be liberated, or a phonon could cause a slight rise in temperature in the cryogenic material. The challenge for dark-matter experiments is to discern the small effects produced by the rare WIMP interactions from the vast number of background events. This background includes cosmic rays and radioactive particles released from the detector and its surroundings. As a result, great care is taken to shield the detectors from comic radiation and to ensure that any radioactive impurities in the detector or shielding material are removed. In the next year or two, both collaborations plan significant upgrades and improvements to their detectors. The DAMA collaboration is planning to increase the mass of its sodium-iodide detector to 250 kg, which will make the experiment far more sensitive to the annual-modulation signal. Meanwhile, the CDMS collaboration plans to move its detector to the Soudan Underground Laboratory, which is located approximately 700 m underground in an abandoned iron mine in Ely, Minnesota. Previous experiments by other groups at the Soudan lab have shown that the background from neutrons will essentially be eliminated. We should therefore learn for certain whether the 13 events observed in the shallow underground laboratory at Stanford are due to neutrons or not. The increased sensitivity of the two experiments - together with a number of other experiments - will allow physicists to search for dark matter in greater detail. The experiments will either discover WIMPs or rule out particles in a large mass range and with a wide range of interaction properties. The discovery of cold dark-matter particles would be one of the most important in the history of physics. It would clarify many questions concerning the birth, evolution and final destiny of our universe. A definitive confirmed discovery would certainly merit a Nobel prize and a distinguished place in history for those who provided the intellectual leadership. (author)

  15. Dark-matter dispute intensifies

    Energy Technology Data Exchange (ETDEWEB)

    Avignone, Frank T. [Department of Physics and Astronomy, University of South Carolina, Columbia, SC (United States)

    2000-04-01

    Recent results from a dark-matter experiment in Italy suggest that the elusive weakly interacting massive particle or WIMP has finally been detected - but a rival experimental collaboration in the US disagrees. The controversy surrounding evidence for the discovery of ''dark matter'' particles has heated up following two conflicting talks given at a conference at the end of February. The papers were presented at the 4th International Symposium on Sources and Detection of Dark Matter/Energy in the Universe held in Marina del Ray, California. For almost 70 years astronomers have known that dust, gas and other ordinary matter cannot account for almost 90% of the mass of many galaxies. The galaxies must contain other ''dark'' matter to explain the orbital motions of stars around their centres. Many astrophysicists, cosmologists and particle physicists have conjectured that this seemingly empty space could be populated by a dense body of massive, but very weakly interacting, particles called WIMPs. Such particles would then provide the gravitational fields needed to keep the stars moving as observed. Since the results of the first experimental efforts to detect these particles were published in 1987, literally dozens of experiments have been performed around the world. Two of the most sensitive experiments to date are the DAMA experiment at the Gran Sasso laboratory in Italy, and the CDMS experiment at Stanford University in the US. The DAMA collaboration - which includes physicists from the University of Rome Tor Vergata, the University of Rome La Sapienza and the Chinese Academy in Beijing - has been searching for WIMPs for several years using a large array of sodium-iodide detectors located 1400 m below ground. The CDMS experiment uses cryogenic detectors and is located just 10 m underground. The collaboration includes researchers from several centres in the US and Russia. Assuming that they do exist, a WIMP will occasionally strike a nucleus in the detector material head-on and cause an elastic recoil. The recoil energy depends on the mass and velocity of the WIMP, together with the mass of the target nucleus. This energy can be measured in several ways, depending on the detector used. A scintillation photon may be emitted, electric charge may be liberated, or a phonon could cause a slight rise in temperature in the cryogenic material. The challenge for dark-matter experiments is to discern the small effects produced by the rare WIMP interactions from the vast number of background events. This background includes cosmic rays and radioactive particles released from the detector and its surroundings. As a result, great care is taken to shield the detectors from comic radiation and to ensure that any radioactive impurities in the detector or shielding material are removed. In the next year or two, both collaborations plan significant upgrades and improvements to their detectors. The DAMA collaboration is planning to increase the mass of its sodium-iodide detector to 250 kg, which will make the experiment far more sensitive to the annual-modulation signal. Meanwhile, the CDMS collaboration plans to move its detector to the Soudan Underground Laboratory, which is located approximately 700 m underground in an abandoned iron mine in Ely, Minnesota. Previous experiments by other groups at the Soudan lab have shown that the background from neutrons will essentially be eliminated. We should therefore learn for certain whether the 13 events observed in the shallow underground laboratory at Stanford are due to neutrons or not. The increased sensitivity of the two experiments - together with a number of other experiments - will allow physicists to search for dark matter in greater detail. The experiments will either discover WIMPs or rule out particles in a large mass range and with a wide range of interaction properties. The discovery of cold dark-matter particles would be one of the most important in the history of physics. It would clarify many questions concerning the birth, evolution and final destiny of our universe. A definitive confirmed discovery would certainly merit a Nobel prize and a distinguished place in history for those who provided the intellectual leadership. (author)

  16. Progress in Reversing the HIV Epidemic through Intensified Access to Antiretroviral Therapy: Results from a Nationally Representative Population-Based Survey in Kenya, 2012

    Science.gov (United States)

    Kim, Andrea A.; Mukui, Irene; N’gan’ga, Lucy; Katana, Abraham; Koros, Dan; Wamicwe, Joyce; De Cock, Kevin M.

    2016-01-01

    Background In 2014, the Joint United Nations Programme on HIV/AIDS (UNAIDS) called for 90% of persons living with HIV (PLHIV) to know their status, 90% of these to be on antiretroviral therapy (ART), and 90% of these to be virally suppressed by 2020 (90-90-90). It is not clear whether planned ART scale-up in countries whose eligibility criteria for ART initiation are based on recommendations from the 2013 World Health Organization treatment guidelines will be sufficient to meet UNAIDS' new global targets. Materials and Methods Using data from a nationally representative population-based household survey of persons in Kenya we compared coverage and unmet need associated with HIV diagnosis, ART, and viral suppression among PLHIV aged 15–64 years in 2012 based on criteria outlined in the 2014 national ART guidelines and UNAIDS’ 90-90-90 goals. Estimates were weighted to account for sampling probability and nonresponse. Results Eight in ten PLHIV aged 15–64 years needed ART based on treatment eligibility. Need for treatment based on the national treatment policy was 97.4% of treatment need based on UNAIDS’ 90-90-90 goals, requiring an excess of 24,000 PLHIV to access treatment beyond those eligible for ART to achieve UNAIDS’ 90-90-90 treatment target. The gap in treatment coverage was high, ranging from 43.1% nationally to 52.3% in Nyanza among treatment-eligible PLHIV and 44.6% nationally to 52.4% in Nyanza among all PLHIV. Conclusion Maintaining the current pace of ART scale-up in Kenya will result in thousands of PLHIV unreached, many with high viral load and at-risk of transmitting infection to others. Careful strategies for reaching 90-90-90 will be instrumental in determining whether intensified access to treatment can be achieved to reach all who require ART. PMID:26930291

  17. Usefulness of DICOM headers in the analysis of two biplane X-ray systems setting (image intensifier and flat panel) used in pediatric interventional cardiology in Chile

    International Nuclear Information System (INIS)

    Ubeda, C.; Vergara, F.

    2009-01-01

    The setting of two biplane X ray systems were evaluated (image intensifier (II) and flat panel (PP)), through DICOM tags from 32 images created during the characterization of both systems. The technical parameters adjusted for systems were: 63,8 to 80,0 kV and 15,0 to 388,0 mA, for the system with II and 52,0 to 77,0 kV and 25,0 to 476,0 mA, for the system with PP detector. Both equipment presented a different mA adjustment, when moving from fluoroscopy modes low dose (FL), medium dose (FM) and high dose (FH) to cine mode (CI). Two dosimetric quantities were evaluated, the first one was the dose-area product (DAP) which gave as a result for FB mode, between 0,03 to 0,35 uGycm 2 /image (II) and from 0,05 a 0,69 uGycm 2 /image (PP), when the polymethyl methacrylate (PMMA) thickness was incremented from 4 to 16 cm. In cine mode the DAP quantity showed, percentage values from 24 to -1 % for the same PMMA increment. Skin cumulative dose was the second quantity evaluated and showed an increment of incident air kerma (KAI)/image in factors from 17 to 35 (II) and 15 to 28 (PP) when used in CI mode instead of FB mode, to the different PMMA thicknesses used. This dose increment for CI mode must be considered by cardiologists, to use the fluoroscopic run as an alternative to document part of the procedures when there is no need to use a high quality image (author)

  18. Compromised local control due to treatment interruptions and late treatment breaks in early glottic cancer: Population-based outcomes study supporting need for intensified treatment schedules

    International Nuclear Information System (INIS)

    Groome, Patti A.; O'Sullivan, Brian; Mackillop, William J.; Jackson, Lynda D.; Schulze, Karleen M.Math.; Irish, Jonathan C.; Warde, Padraig R.; Schneider, Ken M.; Mackenzie, Robert G.; Hodson, D. Ian; Hammond, J. Alex; Gulavita, Sunil P.P.; Eapen, Libni J.; Dixon, Peter F. M.B.; Bissett, Randy J.

    2006-01-01

    Purpose: This population-based study describes the treatment of early glottic cancer in Ontario, Canada and assesses whether treatment variations were associated with treatment effectiveness. Methods and Materials: We studied 491 T1N0 and 213 T2N0 patients. Data abstracted from charts included age, sex, stage, treatment details, disease control, and survival. Results: The total dose ranged from 50 to 70 Gy, and the daily dose ranged from 1.9 to 2.8 Gy. In 90%, treatment duration was between 25 and 50 days. Field sizes, field reductions, beam arrangement, and beam energy varied. Late treatment breaks occurred in 13.6% of T1N0 and 27.1% of T2N0 cases. Local control was comparable to other reports for T1N0 (82% at 5 years), but was only 63.2% in T2N0. Variables associated with local failure in T1N0 were age less than 49 years (relative risk [RR], 3.21; 95% confidence interval [CI], 1.49-6.90) and >3 treatment interruption days (RR, 2.43; 95% CI, 1.00-5.91). In T2N0, these were field reduction (RR, 2.33; 95% CI, 1.23-4.42) and late treatment breaks (RR, 2.19; 95% CI, 1.09-4.41). Conclusion: Some aspects of treatment for early glottic cancer were associated with worse local control. Problems with protracted treatment are of particular concern, underscoring the need for randomized studies to intensify radiotherapy

  19. Higher serum cholesterol is associated with intensified age-related neural network decoupling and cognitive decline in early- to mid-life.

    Science.gov (United States)

    Spielberg, Jeffrey M; Sadeh, Naomi; Leritz, Elizabeth C; McGlinchey, Regina E; Milberg, William P; Hayes, Jasmeet P; Salat, David H

    2017-06-01

    Mounting evidence indicates that serum cholesterol and other risk factors for cardiovascular disease intensify normative trajectories of age-related cognitive decline. However, the neural mechanisms by which this occurs remain largely unknown. To understand the impact of cholesterol on brain networks, we applied graph theory to resting-state fMRI in a large sample of early- to mid-life Veterans (N = 206, Mean age  = 32). A network emerged (centered on the banks of the superior temporal sulcus) that evidenced age-related decoupling (i.e., decreased network connectivity with age), but only in participants with clinically-elevated total cholesterol (≥180 mg/dL). Crucially, decoupling in this network corresponded to greater day-to-day disability and mediated age-related declines in psychomotor speed. Finally, examination of network organization revealed a pattern of age-related dedifferentiation for the banks of the superior temporal sulcus, again present only with higher cholesterol. More specifically, age was related to decreasing within-module communication (indexed by Within-Module Degree Z-Score) and increasing between-module communication (indexed by Participation Coefficient), but only in participants with clinically-elevated cholesterol. Follow-up analyses indicated that all findings were driven by low-density lipoprotein (LDL) levels, rather than high-density lipoprotein (HDL) or triglycerides, which is interesting as LDL levels have been linked to increased risk for cardiovascular disease, whereas HDL levels appear inversely related to such disease. These findings provide novel insight into the deleterious effects of cholesterol on brain health and suggest that cholesterol accelerates the impact of age on neural trajectories by disrupting connectivity in circuits implicated in integrative processes and behavioral control. Hum Brain Mapp 38:3249-3261, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  20. Short-Term Intensified Cycle Training Alters Acute and Chronic Responses of PGC1α and Cytochrome C Oxidase IV to Exercise in Human Skeletal Muscle

    Science.gov (United States)

    Stepto, Nigel K.; Benziane, Boubacar; Wadley, Glenn D.; Chibalin, Alexander V.; Canny, Benedict J.; Eynon, Nir; McConell, Glenn K.

    2012-01-01

    Reduced activation of exercise responsive signalling pathways have been reported in response to acute exercise after training; however little is known about the adaptive responses of the mitochondria. Accordingly, we investigated changes in mitochondrial gene expression and protein abundance in response to the same acute exercise before and after 10-d of intensive cycle training. Nine untrained, healthy participants (mean±SD; VO2peak 44.1±17.6 ml/kg/min) performed a 60 min bout of cycling exercise at 164±18 W (72% of pre-training VO2peak). Muscle biopsies were obtained from the vastus lateralis muscle at rest, immediately and 3 h after exercise. The participants then underwent 10-d of cycle training which included four high-intensity interval training sessions (6×5 min; 90–100% VO2peak) and six prolonged moderate-intensity sessions (45–90 min; 75% VO2peak). Participants repeated the pre-training exercise trial at the same absolute work load (64% of pre-training VO2peak). Muscle PGC1-α mRNA expression was attenuated as it increased by 11- and 4- fold (Pexercise pre- and post-training, respectively. PGC1-α protein expression increased 1.5 fold (Pexercise pre-training with no further increases after the post-training exercise bout. RIP140 protein abundance was responsive to acute exercise only (Pexercise pre- and post-training. These findings demonstrate that short-term intensified training promotes increased mitochondrial gene expression and protein abundance. Furthermore, acute indicators of exercise-induced mitochondrial adaptation appear to be blunted in response to exercise at the same absolute intensity following short-term training. PMID:23285255

  1. Je fais crise d’angoisse sur crise d’angoisse, de pire en pire : comment intensifier la peur dans le discours sur la « fin du monde »

    Directory of Open Access Journals (Sweden)

    Małgorzata Niziołek

    2015-12-01

    Full Text Available This paper analyses the comments of internet users related to the news about the end of the world on the 21st of December, 2012. We consider which linguistic constructions allow fear to intensify. We indicate a semantic model of intensification which corresponds to the causative construction: Si Intens causes Si intens [very p (quality / condition] causes [very q (act / new condition], constituting the basis for the linguistic expression of fear. Because the end of the world is an unimaginable event, it causes fear – a primary and universal emotion. Surfers exploit various (formal, lexical, graphic, etc. procedures which provide an opportunity for the feelings of fear to intensify. The intensification of the cause (approaching end of the world provokes an intensification of the consequence (feeling of fear. The analysis is part of the work of the research group DiSEM (Discourse Semantics Inference composed of researchers from the Pedagogical University of Cracow.

  2. Depth resolved lattice-charge coupling in epitaxial BiFeO3 thin film

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hyeon Jun; Lee, Sung Su; Kwak, Jeong Hun; Kim, Young-Min; Jeong, Hu Young; Borisevich, Albina Y.; Lee, Su Yong; Noh, Do Young; Kwon, Owoong; Kim, Yunseok; Jo, Ji Young

    2016-12-01

    For epitaxial films, a critical thickness (tc) can create a phenomenological interface between a strained bottom layer and a relaxed top layer. Here, we present an experimental report of how the tc in BiFeO3 thin films acts as a boundary to determine the crystalline phase, ferroelectricity, and piezoelectricity in 60 nm thick BiFeO3/SrRuO3/SrTiO3 substrate. We found larger Fe cation displacement of the relaxed layer than that of strained layer. In the time-resolved X-ray microdiffraction analyses, the piezoelectric response of the BiFeO3 film was resolved into a strained layer with an extremely low piezoelectric coefficient of 2.4 pm/V and a relaxed layer with a piezoelectric coefficient of 32 pm/V. The difference in the Fe displacements between the strained and relaxed layers is in good agreement with the differences in the piezoelectric coefficient due to the electromechanical coupling.

  3. Event-driven charge-coupled device design and applications therefor

    Science.gov (United States)

    Doty, John P. (Inventor); Ricker, Jr., George R. (Inventor); Burke, Barry E. (Inventor); Prigozhin, Gregory Y. (Inventor)

    2005-01-01

    An event-driven X-ray CCD imager device uses a floating-gate amplifier or other non-destructive readout device to non-destructively sense a charge level in a charge packet associated with a pixel. The output of the floating-gate amplifier is used to identify each pixel that has a charge level above a predetermined threshold. If the charge level is above a predetermined threshold the charge in the triggering charge packet and in the charge packets from neighboring pixels need to be measured accurately. A charge delay register is included in the event-driven X-ray CCD imager device to enable recovery of the charge packets from neighboring pixels for accurate measurement. When a charge packet reaches the end of the charge delay register, control logic either dumps the charge packet, or steers the charge packet to a charge FIFO to preserve it if the charge packet is determined to be a packet that needs accurate measurement. A floating-diffusion amplifier or other low-noise output stage device, which converts charge level to a voltage level with high precision, provides final measurement of the charge packets. The voltage level is eventually digitized by a high linearity ADC.

  4. Design, fabrication, and evaluation of charge-coupled devices with aluminum-anodized-aluminum gates

    Science.gov (United States)

    Gassaway, J. D.; Causey, W. H., Jr.

    1977-01-01

    A 4-phase, 49 1/2 bit CCD shift register was designed and fabricated using two levels of aluminum metallization with anodic Al2O3 insulation separating the layers. Test circuitry was also designed and constructed. A numerical analysis of an MOS-RC transmission line was made and results are given to characterize performance for various conductivities. The electrical design of the CCD included a low-noise dual-gate input and a balanced floating diffusion output circuit. Metallization was accomplished both by low voltage DC sputtering and thermal evaporation. The audization was according to published procedures using a buffered tartaric acid bath. Approximately 20 wafers were processed with 50 complete chips per wafer. All devices failed by shorting between the metal levels at some point. Experimental procedures eliminated temperature effects from sintering and drying, anodic oxide thickness, edge effects, photoresist stripping procedures, and metallization techniques as the primary causes of failure. It was believed from a study of SEM images that protuberances (hillocks) grow up from the first level metal through the oxide either causing a direct short or producing a weak, highly stressed insulation point which fails at low voltage. The cause of these hillocks is unknown; however, they have been observed to grow during temperature excursions to 470 C.

  5. Two-dimensional polarimeter with a charge-coupled-device image sensor and a piezoelastic modulator.

    Science.gov (United States)

    Povel, H P; Keller, C U; Yadigaroglu, I A

    1994-07-01

    We present the first measurements and scientific observations of the solar photosphere obtained with a new two-dimensional polarimeter based on piezoelastic modulators and synchronous demodulation in a CCD imager. This instrument, which is developed for precision solar-vector polarimetry, contains a specially masked CCD that has every second row covered with an opaque mask. During exposure the charges are shifted back and forth between covered and light-sensitive rows synchronized with the modulation. In this way Stokes I and one of the other Stokes parameters can be recorded. Since the charge shifting is performed at frequencies well above the seeing frequencies and both polarization states are measured with the same pixel, highly sensitive and accurate polarimetry is achieved. We have tested the instrument in laboratory conditions as well as at three solar telescopes.

  6. Charge-coupled devices as positron sensitive detectors of x-radiation

    International Nuclear Information System (INIS)

    Volkov, G.S.; Zazhivikhin, V.V.; Zajtsev, V.I.; Mishevskij, V.O.

    1996-01-01

    Results of theoretical and experimental studies on the sensitivity and spatial resolution of devices with a charge link (CLD) within the X-radiation energy range are described. The areas of the device application are considered

  7. Escape peak ratios in silicon X-ray charge coupled devices (CCDs)

    International Nuclear Information System (INIS)

    McCarthy, K.J.; Owens, A.; Keay, A.

    1997-01-01

    The intensity of the escape peak from the CCDs developed for the Joint European X-ray Telescope (JET-X) has been investigated over the energy range 2-10 keV. Both measured and calculated escape peak ratios (i.e., the ratio of counts in the escape peak to the sum of the counts in the escape and main peaks) are found to be in excellent agreement for all event sizes (i.e., single pixel events, 1 and 2 pixel events, etc.). Using a Monte Carlo simulation the escape peak ratio has been investigated as a function of pixel size and depletion depth. For completeness, we list the energy dependent parameterised forms for five CCDs used in three major astronomy missions. (orig.)

  8. Application of charge coupled devices as spatially-resolved detectors for X-ray spectrograph

    Energy Technology Data Exchange (ETDEWEB)

    Attelan-Langlet, S; Etlicher, B [Ecole Polytechnique, Palaiseau (France); Mishenskij, V O; Papazyan, Yu V; Smirnov, V P; Volkov, G S; Zajtsev, V I [Inst. for Thermonuclear and Innovation Investigations, Troitsk (Russian Federation)

    1997-12-31

    An X-ray crystal spectrograph which contains a CCD linear array as the position-sensitive detector is described. Radiation detection is performed directly onto CCD. The spectrograph has a limit of sensitivity at about 2 J/(A.ster), spectral resolution about 1000 and dynamic range 100-120. The device operates on-line with IBM-PC based control system. Software provides all data acquisition and treatment. Output spectra are presented in absolute units. The device was used during composite Z-pinch experiments at pulse-power installations ``Angara-5-1`` (TRINITI, Troitsk, Russia) and ``GAEL`` (Ecole Polytechnique, Palaiseau, France). Currently the spectrograph is included in the set of diagnostics of the ``Angara-5-1`` facility. Some of the spectra obtained are presented and discussed. (author). 4 figs., 9 refs.

  9. Controllable synthesis of (NH4)Fe2(PO4)2(OH)·2H2O using two-step route: Ultrasonic-intensified impinging stream pre-treatment followed by hydrothermal treatment.

    Science.gov (United States)

    Dong, Bin; Li, Guang; Yang, Xiaogang; Chen, Luming; Chen, George Z

    2018-04-01

    (NH 4 )Fe 2 (PO 4 ) 2 (OH)·2H 2 O samples with different morphology are successfully synthesized via two-step synthesis route - ultrasonic-intensified impinging stream pre-treatment followed by hydrothermal treatment (UIHT) method. The effects of the adoption of ultrasonic-intensified impinging stream pre-treatment, reagent concentration (C), pH value of solution and hydrothermal reaction time (T) on the physical and chemical properties of the synthesised (NH 4 )Fe 2 (PO 4 ) 2 (OH)·2H 2 O composites and FePO 4 particles were systematically investigated. Nano-seeds were firstly synthesized using the ultrasonic-intensified T-mixer and these nano-seeds were then transferred into a hydrothermal reactor, heated at 170 °C for 4 h. The obtained samples were characterized by utilising XRD, BET, TG-DTA, SEM, TEM, Mastersizer 3000 and FTIR, respectively. The experimental results have indicated that the particle size and morphology of the obtained samples are remarkably affected by the use of ultrasonic-intensified impinging stream pre-treatment, hydrothermal reaction time, reagent concentration, and pH value of solution. When such (NH 4 )Fe 2 (PO 4 ) 2 (OH)·2H 2 O precursor samples were transformed to FePO 4 products after sintering at 650 °C for 10 h, the SEM images have clearly shown that both the precursor and the final product still retain their monodispersed spherical microstructures with similar particle size of about 3 μm when the samples are synthesised at the optimised condition. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. The diagnostic performance of a single GeneXpert MTB/RIF assay in an intensified tuberculosis case finding survey among HIV-infected prisoners in Malaysia.

    Directory of Open Access Journals (Sweden)

    Haider Abdulrazzaq Abed Al-Darraji

    Full Text Available Delays in tuberculosis (TB diagnosis, particularly in prisons, is associated with detrimental outcomes. The new GeneXpert MTB/RIF assay (Xpert offers accurate and rapid diagnosis of active TB, but its performance in improving case detection in high-transmission congregate settings has yet to be evaluated. We assessed the diagnostic accuracy of a single Xpert assay in an intensified case finding survey among HIV-infected prisoners in Malaysia.HIV-infected prisoners at a single site provided two early-morning sputum specimens to be examined using fluorescence smear microscopy, BACTEC MGIT 960 liquid culture and a single Xpert. The sensitivity, specificity, negative and positive predictive values of Xpert were calculated relative to gold-standard results using MGIT 960 liquid culture. Relevant clinical and demographic data were used to examine correlates of active TB disease.The majority of enrolled subjects with complete data (N=125 were men (90.4%, age <40 years (61.6% and had injected drugs (75.2%. Median CD4 lymphocyte count was 337 cells/µL (IQR 149-492; only 19 (15.2% were receiving antiretroviral therapy. Of 15 culture-positive TB cases, single Xpert assay accurately detected only eight previously undiagnosed TB cases, resulting in a sensitivity, specificity, positive predictive value and negative predictive value of 53.3% (95% CI 30.12-75.2%, 100% (95% CI 96.6-100%, 100% (95% CI 67.56-100% and 94.0% (95% CI 88.2-97.1%, respectively. Only 1 of 15 (6.7% active TB cases was smear-positive. The prevalence (12% of undiagnosed active pulmonary TB (15 of 125 prisoners was high and associated with longer duration of drug use (AOR 1.14, 95% CI 1.03-1.26, for each year of drug use.Single Xpert assay improved TB case detection and outperformed AFB smear microscopy, but yielded low screening sensitivity. Further examination of the impact of HIV infection on the diagnostic performance of the new assay alongside other screening methods in correctional

  11. Technology-Intensified Diabetes Education Study (TIDES) in African Americans with type 2 diabetes: study protocol for a randomized controlled trial.

    Science.gov (United States)

    Williams, Joni S; Lynch, Cheryl P; Knapp, Rebecca G; Egede, Leonard E

    2014-11-25

    Compared to American Whites, African Americans have a higher prevalence of type 2 diabetes mellitus (T2DM), experiencing poorer metabolic control and greater risks for complications and death. Patient-level factors, such as diabetes knowledge, self-management skills, empowerment, and perceived control, account for >90% of the variance observed in outcomes between these racial groups. There is strong evidence that self-management interventions that include telephone-delivered diabetes education and skills training are effective at improving metabolic control in diabetes. Web-based home telemonitoring systems in conjunction with active care management are also effective ways to lower glycosylated hemoglobin A1c values when compared to standard care, and provide feedback to patients; however, there are no studies in African Americans with poorly controlled T2DM that examine the use of technology-based feedback to tailor or augment diabetes education and skills training. This study provides a unique opportunity to address this gap in the literature. We describe an ongoing 4-year randomized clinical trial, which will test the efficacy of a technology-intensified diabetes education and skills training (TIDES) intervention in African Americans with poorly controlled T2DM. Two hundred male and female AfricanAmerican participants, 21 years of age or older and with a glycosylated hemoglobin A1c level ≥ 8%, will be randomized into one of two groups for 12 weeks of telephone interventions: (1) TIDES intervention group or (2) a usual-care group. Participants will be followed for 12 months to ascertain the effect of the interventions on glycemic control. Our primary hypothesis is that, among African Americans with poorly controlled T2DM, patients randomized to the TIDES intervention will have significantly greater reduction in glycosylated hemoglobin A1c at 12 months of follow-up compared to the usual-care group. Results from this study will add to the current literature

  12. Late Holocene dune mobilizations in the northwestern Negev dunefield, Israel: A response to combined anthropogenic activity and short-term intensified windiness

    Science.gov (United States)

    Roskin, Joel; Katra, Itzhak; Blumberg, Dan G.

    2013-04-01

    The study of the effects of past climates on ancient cultures is usually based on geologic records pertaining to rainfall and temperature fluctuations and shifts. This study proposes a paradigm of anthropogenic activity and windiness fluctuations to explain aeolian sedimentation and dune mobilization in the northwestern (NW) Negev Desert dunefield (Israel). The proposed paradigm contributes a different approach to estimating the effect of climate changes on the unprecedented agricultural and urban settlement expansion during the late Roman to Early Islamic period in the northern and central Negev Desert. This study builds upon the late Holocene cluster of luminescence ages of Roskin et al. (Age, origin and climatic controls on vegetated linear dunes in the northwestern Negev Desert (Israel), Quaternary Science Reviews 30 (2011), 1649-1674) coupled with analysis of archaeological finds and historical texts. We suggest that whereas the NW Negev dunefield was generally stable during the Holocene, intermittent dune mobilization during the late Holocene, at ~1.8 ka and mostly 1.4-1.1 ka (~600-900 CE), are linked to periods of human occupation. The idea that the last glacial dune encroachments alone that formed the NW Negev dunefield is connected to cold-event windy climates that may have intensified East Mediterranean cyclonic winter storms, cannot explain the late Holocene dune mobilizations. We conceptually model a connection between late Holocene dune mobilization, widespread anthropogenic occupation and activity, and windiness. We maintain that historic grazing and uprooting shrubs for fuel in the past by nomads and sedentary populations led to decimation of dune stabilizers, biogenic soil crusts and vegetation, causing dune erodibility and low-grade activity. Short-term events of amplified wind power in conjunction with periods of augmented anthropogenic activity that triggered major events of dune mobilization (elongation) and accretion have been preserved in the

  13. Rapid preparation of high electrochemical performance LiFePO4/C composite cathode material with an ultrasonic-intensified micro-impinging jetting reactor.

    Science.gov (United States)

    Dong, Bin; Huang, Xiani; Yang, Xiaogang; Li, Guang; Xia, Lan; Chen, George

    2017-11-01

    A joint chemical reactor system referred to as an ultrasonic-intensified micro-impinging jetting reactor (UIJR), which possesses the feature of fast micro-mixing, was proposed and has been employed for rapid preparation of FePO 4 particles that are amalgamated by nanoscale primary crystals. As one of the important precursors for the fabrication of lithium iron phosphate cathode, the properties of FePO 4 nano particles significantly affect the performance of the lithium iron phosphate cathode. Thus, the effects of joint use of impinging stream and ultrasonic irradiation on the formation of mesoporous structure of FePO 4 nano precursor particles and the electrochemical properties of amalgamated LiFePO 4 /C have been investigated. Additionally, the effects of the reactant concentration (C=0.5, 1.0 and 1.5molL -1 ), and volumetric flow rate (V=17.15, 51.44, and 85.74mLmin -1 ) on synthesis of FePO 4 ·2H 2 O nucleus have been studied when the impinging jetting reactor (IJR) and UIJR are to operate in nonsubmerged mode. It was affirmed from the experiments that the FePO 4 nano precursor particles prepared using UIJR have well-formed mesoporous structures with the primary crystal size of 44.6nm, an average pore size of 15.2nm, and a specific surface area of 134.54m 2 g -1 when the reactant concentration and volumetric flow rate are 1.0molL -1 and 85.74mLmin -1 respectively. The amalgamated LiFePO 4 /C composites can deliver good electrochemical performance with discharge capacities of 156.7mAhg -1 at 0.1C, and exhibit 138.0mAhg -1 after 100 cycles at 0.5C, which is 95.3% of the initial discharge capacity. Copyright © 2017. Published by Elsevier B.V.

  14. Reduced risk of heart failure with intensified multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: 21 years of follow-up in the randomised Steno-2 study.

    Science.gov (United States)

    Oellgaard, Jens; Gæde, Peter; Rossing, Peter; Rørth, Rasmus; Køber, Lars; Parving, Hans-Henrik; Pedersen, Oluf

    2018-05-30

    In type 2 diabetes mellitus, heart failure is a frequent, potentially fatal and often forgotten complication. Glucose-lowering agents and adjuvant therapies modify the risk of heart failure. We recently reported that 7.8 years of intensified compared with conventional multifactorial intervention in individuals with type 2 diabetes and microalbuminuria in the Steno-2 study reduced the risk of cardiovascular disease and prolonged life over 21.2 years of follow-up. In this post hoc analysis, we examine the impact of intensified multifactorial intervention on the risk of hospitalisation for heart failure. One hundred and sixty individuals were randomised to conventional or intensified multifactorial intervention, using sealed envelopes. The trial was conducted using the Prospective, Randomised, Open, Blinded Endpoints (PROBE) design. After 7.8 years, all individuals were offered intensified therapy and the study continued as an observational follow-up study for an additional 13.4 years. Heart-failure hospitalisations were adjudicated from patient records by an external expert committee blinded for treatment allocation. Event rates were compared using a Cox regression model adjusted for age and sex. Eighty patients were assigned to each treatment group. Ten patients undergoing intensive therapy vs 24 undergoing conventional therapy were hospitalised for heart failure during follow-up. The HR (95% CI) was 0.30 (0.14, 0.64), p = 0.002 in the intensive-therapy group compared with the conventional-therapy group. Including death in the endpoint did not lead to an alternate overall outcome; HR 0.51 (0.34, 0.76), p = 0.001. In a pooled cohort analysis, an increase in plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) during the first two years of the trial was associated with incident heart failure. Intensified, multifactorial intervention for 7.8 years in type 2 diabetic individuals with microalbuminuria reduced the risk of hospitalisation for heart

  15. Intensified Local Resource Mobilization for the Polio Eradication Initiative: The Experience of World Health Organization in Nigeria During 2008-2015.

    Science.gov (United States)

    Yehualashet, Yared G; Horton, Janet; Mkanda, Pascal; Vaz, Rui G; Afolabi, Oluwole; Gashu, Sisay G; Banda, Richard; O'Malley, Helena; Nsubuga, Peter

    2016-05-01

    Since the World Health Assembly (WHA) resolved in 1988 to eradicate poliovirus, several rounds of immunization campaigns have been conducted by member states. By 2000, with the support of the Global Polio Eradication Initiative (GPEI) partners, the number of polio cases decreased by 99%. Eradicating the remaining 1% proved to be more challenging. Although the GPEI, being the largest public health project, required >$9 billion between 1988 and 2012, economic analysis showed the estimated incremental net benefits of $40 billion-$50 billion between 1988 and 2035. In 2012, the WHA declared that the completion of poliovirus eradication is a programmatic emergency for global public health. Nigeria, as one of 3 remaining polio-endemic countries, developed an emergency plan to interrupt the transmission of poliovirus. The plan included the introduction or scale-up of various new innovations and strategies, which had substantial financial implication. This is a retrospective study to document the intensified resource mobilization efforts made by the World Health Organization (WHO) in Nigeria to meet the increased financial requirements and bridge the remaining gap in funding. In addition to the established coordination platforms, the WHO Nigeria Country Office team directly engaged with national authorities, donors, and partners throughout the process of resource requirement analysis, project appraisals, proposal development, and implementation of activities, joint monitoring, and evaluation exercises. The office strengthened its capacity for direct funds disbursement and systematic implementation of a rigorous accountability framework. Between 2008 and May 2015, $538 million was mobilized locally, of which 82% was mobilized since 2012. The percentage of the total funding requirements that were locally mobilized averaged 31% between 2008 and 2011 and increased to 70% between 2012 and May 2015. During the same period, the WHO Nigeria Country Office team produced and

  16. Intensified Local Resource Mobilization for the Polio Eradication Initiative: The Experience of World Health Organization in Nigeria During 2008–2015

    Science.gov (United States)

    Yehualashet, Yared G.; Horton, Janet; Mkanda, Pascal; Vaz, Rui G.; Afolabi, Oluwole; Gashu, Sisay G.; Banda, Richard; O'Malley, Helena; Nsubuga, Peter

    2016-01-01

    Background. Since the World Health Assembly (WHA) resolved in 1988 to eradicate poliovirus, several rounds of immunization campaigns have been conducted by member states. By 2000, with the support of the Global Polio Eradication Initiative (GPEI) partners, the number of polio cases decreased by 99%. Eradicating the remaining 1% proved to be more challenging. Although the GPEI, being the largest public health project, required >$9 billion between 1988 and 2012, economic analysis showed the estimated incremental net benefits of $40 billion–$50 billion between 1988 and 2035. In 2012, the WHA declared that the completion of poliovirus eradication is a programmatic emergency for global public health. Nigeria, as one of 3 remaining polio-endemic countries, developed an emergency plan to interrupt the transmission of poliovirus. The plan included the introduction or scale-up of various new innovations and strategies, which had substantial financial implication. Methods. This is a retrospective study to document the intensified resource mobilization efforts made by the World Health Organization (WHO) in Nigeria to meet the increased financial requirements and bridge the remaining gap in funding. In addition to the established coordination platforms, the WHO Nigeria Country Office team directly engaged with national authorities, donors, and partners throughout the process of resource requirement analysis, project appraisals, proposal development, and implementation of activities, joint monitoring, and evaluation exercises. The office strengthened its capacity for direct funds disbursement and systematic implementation of a rigorous accountability framework. Results. Between 2008 and May 2015, $538 million was mobilized locally, of which 82% was mobilized since 2012. The percentage of the total funding requirements that were locally mobilized averaged 31% between 2008 and 2011 and increased to 70% between 2012 and May 2015. During the same period, the WHO Nigeria

  17. How much will it cost to eradicate lymphatic filariasis? An analysis of the financial and economic costs of intensified efforts against lymphatic filariasis.

    Directory of Open Access Journals (Sweden)

    Randee J Kastner

    2017-09-01

    elimination scenario, which includes countries that previously undertook MDA, is estimated to cost 929 million USD (95% Credible Interval: 884m-972m. Proceeding to eradication is anticipated to require a higher financial investment, estimated at 1.24 billion USD (1.17bn-1.30bn in the eradication III scenario (immediate scale-up, with eradication II (intensified scale-up projected at 1.27 billion USD (1.21bn-1.33bn, and eradication I (slow scale-up estimated at 1.29 billion USD (1.23bn-1.34bn. The economic costs of the eradication III scenario are estimated at approximately 7.57 billion USD (7.12bn-7.94bn, while the elimination scenario is projected to have an economic cost of 5.21 billion USD (4.91bn-5.45bn. Countries in the AFRO region will require the greatest investment to reach elimination or eradication, but also stand to gain the most in cost savings. Across all scenarios, capacity strengthening and advocacy and communication represent the greatest financial costs, whereas mapping, post-MDA surveillance, and administration comprise the least.Though challenging to implement, our results indicate that financial and economic savings are greatest under the eradication III scenario. Thus, if eradication for LF is the objective, accelerated scale-up is projected to be the best investment.

  18. How much will it cost to eradicate lymphatic filariasis? An analysis of the financial and economic costs of intensified efforts against lymphatic filariasis.

    Science.gov (United States)

    Kastner, Randee J; Sicuri, Elisa; Stone, Christopher M; Matwale, Gabriel; Onapa, Ambrose; Tediosi, Fabrizio

    2017-09-01

    , which includes countries that previously undertook MDA, is estimated to cost 929 million USD (95% Credible Interval: 884m-972m). Proceeding to eradication is anticipated to require a higher financial investment, estimated at 1.24 billion USD (1.17bn-1.30bn) in the eradication III scenario (immediate scale-up), with eradication II (intensified scale-up) projected at 1.27 billion USD (1.21bn-1.33bn), and eradication I (slow scale-up) estimated at 1.29 billion USD (1.23bn-1.34bn). The economic costs of the eradication III scenario are estimated at approximately 7.57 billion USD (7.12bn-7.94bn), while the elimination scenario is projected to have an economic cost of 5.21 billion USD (4.91bn-5.45bn). Countries in the AFRO region will require the greatest investment to reach elimination or eradication, but also stand to gain the most in cost savings. Across all scenarios, capacity strengthening and advocacy and communication represent the greatest financial costs, whereas mapping, post-MDA surveillance, and administration comprise the least. Though challenging to implement, our results indicate that financial and economic savings are greatest under the eradication III scenario. Thus, if eradication for LF is the objective, accelerated scale-up is projected to be the best investment.

  19. Joint two-dimensional observations of ground magnetic and ionospheric electric fields associated with auroral zone currents 1. Three-dimensional current flows associated with a substorm-intensified eastward electrojet

    International Nuclear Information System (INIS)

    Baumjohann, W.; Untiedt, J.; Greenwald, R.A.

    1980-01-01

    Two-dimensional distributions of ground magnetic and ionospheric electric fields in the evening sector auroral oval have been simultaneously observed by the Scandinavian Magnetometer Array and the Scandinavian Twin Auroral Radar Experiment (Stare) radars, respectively, on February 15, 1977. They were associated with varying, substorm-intensified, eastward electrojet current systems of the western, middle, and eastern segment of the eastward electrojet. We conclude that the substorm-intensified eastward electroject was a nearly pure Hall current driven by northward electric fields. The observed eastward increase of the current in the western segment of the electrojet was due to a gradual enhancement of the Hall conductivity. Here, the electrojet was fed by a broad sheet of net downward field-aligned current. During one period, the eastern-terminating part of the eastward electrojet diverged up the field lines in a rather local area because of a strong longitudinal decrease in the northward-directed electric field. On another occasion, it diverged northward within the ionosphere and joined the westward-flowing current because of a rotation of the northward electric field with increasing latitude through west- to southward. These two observed mechanisms of current divergence in the region where eastward and westward electrojects coexist may shed some new light on the controversy over the existence of upward field-aligned current flow in the Harang discontinuity

  20. Effects of intensified health education program on maintenance hemodialysis patients with hyperkalaemia%强化健康教育模式在维持性血液透析高钾患者中的应用

    Institute of Scientific and Technical Information of China (English)

    白英; 赵恩路; 王洪霞

    2012-01-01

    Objective To explore the effects of intensified health education program on maintenance hemodialysis (MHD) patients with hyperkalaemia. Methods 42 MHD patients were given intensified health education for two months, including lectures, individual instructions, group discussions, handouts for self-study and diet recording. Results The blood kalium level in the 42 patients was (5.46 ± 0.85)mmol/L, the dietary kalium intake was (1 337.07 ± 664.38)mg/d, the blood kalium went up in 24 patients before education. After education, the blood kalium was (5.08 ± 0.57)mmol/L, dietary kalium intake was (896.33 ± 412.02)mg/d, and the blood kalium in 11 patients went up. The differences in the blood kalium level and dietary kalium intake between pre- and post-education were significant (all P < 0.05). Conclusion Intensified health education may be effective for contain dietary kalium intake and thus lower the blood kalium level before maintenance hemodialysis.%目的 探讨强化健康教育模式在维持性血液透析(maintenance hemodialysis,MHD)高钾患者中的应用效果.方法 对42例MHD患者进行为期2个月强化健康教育,包括集体授课、个性化指导、讨论、发放资料、饮食记录.比较健康教育前后患者透析前血钾及食物中钾的摄入情况.结果 教育前患者血钾为(5.46±0.85)mmol/L,饮食摄入钾为(1337.07±664.38)mg/d,有24例(57.14%)患者血钾升高;教育后患者血钾为( 5.08±0.57) mmol/L,饮食摄入钾为(896.33±412.02)mg/d,有11例(26.19%)患者血钾升高,教育前后比较,均P< 0.05,差异具有统计学意义.结论 强化健康教育能有效控制MHD患者饮食中钾的摄入量,从而降低患者透析前血钾水平.

  1. Short- and Long-Term Quality of Life and Bowel Function in Patients With MRI-Defined, High-Risk, Locally Advanced Rectal Cancer Treated With an Intensified Neoadjuvant Strategy in the Randomized Phase 2 EXPERT-C Trial

    International Nuclear Information System (INIS)

    Sclafani, Francesco; Peckitt, Clare; Cunningham, David; Tait, Diana; Giralt, Jordi; Glimelius, Bengt; Keränen, Susana Roselló; Bateman, Andrew; Hickish, Tamas; Tabernero, Josep; Thomas, Janet; Brown, Gina; Oates, Jacqueline; Chau, Ian

    2015-01-01

    Objective: Intensified preoperative treatments have been increasingly investigated in locally advanced rectal cancer (LARC), but limited data are available for the impact of these regimens on quality of life (QoL) and bowel function (BF). We assessed these outcome measures in EXPERT-C, a randomized phase 2 trial of neoadjuvant capecitabine combined with oxaliplatin (CAPOX), followed by chemoradiation therapy (CRT), total mesorectal excision, and adjuvant CAPOX with or without cetuximab in magnetic resonance imaging-defined, high-risk LARC. Methods and Materials: QoL was assessed using the European Organization for Research and Treatment of Cancer QLQ-C30 and QLQ-CR29 questionnaires. Bowel incontinence was assessed using the modified Fecal Incontinence Severity Index questionnaire. Results: Compared to baseline, QoL scores during preoperative treatment were better for symptoms associated with the primary tumor in the rectum (blood and mucus in stool, constipation, diarrhea, stool frequency, buttock pain) but worse for global health status, role functioning, and symptoms related to the specific safety profile of each treatment modality. During follow-up, improved emotional functioning and lessened anxiety and insomnia were observed, but deterioration of body image, increased urinary incontinence, less sexual interest (men), and increased impotence and dyspareunia were observed. Cetuximab was associated with a deterioration of global health status during neoadjuvant chemotherapy but did not have any long-term detrimental effect. An improvement in bowel continence was observed after preoperative treatment and 3 years after sphincter-sparing surgery. Conclusions: Intensifying neoadjuvant treatment by administering induction systemic chemotherapy before chemoradiation therapy improves tumor-related symptoms and does not appear to have a significantly detrimental effect on QoL and BF, in both the short and the long term

  2. Short- and Long-Term Quality of Life and Bowel Function in Patients With MRI-Defined, High-Risk, Locally Advanced Rectal Cancer Treated With an Intensified Neoadjuvant Strategy in the Randomized Phase 2 EXPERT-C Trial

    Energy Technology Data Exchange (ETDEWEB)

    Sclafani, Francesco; Peckitt, Clare [The Royal Marsden NHS Foundation Trust, London (United Kingdom); Cunningham, David, E-mail: david.cunningham@rmh.nhs.uk [The Royal Marsden NHS Foundation Trust, London (United Kingdom); Tait, Diana [The Royal Marsden NHS Foundation Trust, London (United Kingdom); Giralt, Jordi [Vall d' Hebron University Hospital, Universitat Autònoma de Barcelona, Department of Medical Oncology, Barcelona (Spain); Glimelius, Bengt [University of Uppsala, Uppsala (Sweden); Keränen, Susana Roselló [Biomedical Research Institute INCLIVA, Department of Hematology and Medical Oncology, University of Valencia (Spain); Bateman, Andrew [Southampton General Hospital, Cancer Sciences Unit, University of Southampton (United Kingdom); Hickish, Tamas [Poole Hospital NHS Foundation Trust, Department of Medical Oncology, Bournemouth University (United Kingdom); Tabernero, Josep [Vall d' Hebron University Hospital, Universitat Autònoma de Barcelona, Department of Medical Oncology, Barcelona (Spain); Thomas, Janet; Brown, Gina; Oates, Jacqueline; Chau, Ian [The Royal Marsden NHS Foundation Trust, London (United Kingdom)

    2015-10-01

    Objective: Intensified preoperative treatments have been increasingly investigated in locally advanced rectal cancer (LARC), but limited data are available for the impact of these regimens on quality of life (QoL) and bowel function (BF). We assessed these outcome measures in EXPERT-C, a randomized phase 2 trial of neoadjuvant capecitabine combined with oxaliplatin (CAPOX), followed by chemoradiation therapy (CRT), total mesorectal excision, and adjuvant CAPOX with or without cetuximab in magnetic resonance imaging-defined, high-risk LARC. Methods and Materials: QoL was assessed using the European Organization for Research and Treatment of Cancer QLQ-C30 and QLQ-CR29 questionnaires. Bowel incontinence was assessed using the modified Fecal Incontinence Severity Index questionnaire. Results: Compared to baseline, QoL scores during preoperative treatment were better for symptoms associated with the primary tumor in the rectum (blood and mucus in stool, constipation, diarrhea, stool frequency, buttock pain) but worse for global health status, role functioning, and symptoms related to the specific safety profile of each treatment modality. During follow-up, improved emotional functioning and lessened anxiety and insomnia were observed, but deterioration of body image, increased urinary incontinence, less sexual interest (men), and increased impotence and dyspareunia were observed. Cetuximab was associated with a deterioration of global health status during neoadjuvant chemotherapy but did not have any long-term detrimental effect. An improvement in bowel continence was observed after preoperative treatment and 3 years after sphincter-sparing surgery. Conclusions: Intensifying neoadjuvant treatment by administering induction systemic chemotherapy before chemoradiation therapy improves tumor-related symptoms and does not appear to have a significantly detrimental effect on QoL and BF, in both the short and the long term.

  3. Comparison of dose and image quality of a Flat-panel detector and an image intensifier; Comparacao da dose e qualidade da imagem de um detector Flatpanel e um intensificador de imagem

    Energy Technology Data Exchange (ETDEWEB)

    Lazzaro, M.; Friedrich, B.Q.; Luz, R.M. da; Silva, A.M.M. da, E-mail: marcos.lazzaro@acad.pucrs.br [Pontificia Universidade Catolica do Rio Grande do Sul (PUC-RS), Porto Alegre, RS (Brazil)

    2016-07-01

    With the development of new technologies, have emerged new conversion methods of X-ray image, such as flat panel detectors. The aim of this work is the comparison of entrance surface air kerma (ESAK) and image quality between an image intensifier type of detector (A) and a flat panel (B). The ESAK was obtained by placing a ionization chamber under PMMA simulators of 10, 20 and 30 cm and the image quality was obtained by using the TOR {sup 18}FG simulator. The ESAK to the equipment A is higher when compared to the equipment B. The high contrast resolution is better for the equipment A for all thicknesses of simulators. The equipment A has low contrast resolution with a better viewing threshold for thicknesses of 10 and 20 cm, and a worse performance for 30 cm. It is concluded that the equipment B has ESAK smaller and despite having lower resolution, in almost all cases, have appropriate image quality for diagnosis. (author)

  4. New models intensify the purchase of energy

    International Nuclear Information System (INIS)

    Vesimaeki, P.; Lampinen, J.

    2001-01-01

    Models, designed for planning and optimisation of the purchase of energy, combined with high-quality expertise have an impact on the costs of energy companies. Optimisation has a significant role in power plant investments and in planning the power distribution of wholesale electric power. After the liberation of the electricity markets, the planning of the electricity purchase and the optimisation have obtained totally new roles in estimating the cost effects of present and new customers. Electrowatt-Ekono has developed a windows-based COPSIM software for planning of electric power purchase. The software is in active use in Electrowatt-Ekono. The energy purchase is optimised on yearly basis or on a shorter period by one hour steps based on hourly variation of energy purchase, power plant characteristics, power consumption rates and the prices of the fuels, power and heat. COPSIM takes the effect of external temperature on the power generation of backpressure and gas turbine plants into account. The software optimises also the power distribution of wholesale power. By the software it is possible to model different types of power plants, purchase of power, power sales, different power plant shares, thermal power stations, purchase and sales of heat, heat storage and heat transfer between different heating networks

  5. New intensifier foils in roentgenologic diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Beyer, H K; Schulze, B

    1981-09-01

    The main components of the foils are the carrier layer and the luminescent layer, which are in direct contact through an adhesive layer. Carrier layer and adhesive layer absorb and reflect parts of the light. In order to reduce this effect, modern foils are slightly dyed, mostly in the complementary colour of the emitted light. The luminescent layer is attached to the carrier layer by means of a binder. The mean binder content of the luminescent layer is about 10% of the weight of the luminescent material. The particle or crystal range between 5 and 10 ..mu..m. The luminescent layer thickness varies between 0.1 and 0.5 mm, according to the intensification. The imposing with luminescents consequently increases from 20 up to 100 mg/cm/sup 2/. In most cases the luminescent layer is protected by a thin layer (10 to 20 ..mu..m thick) of a very resistant and well-transparent synthetic resin. A foil combination consists of a front and a rear foil, the rear foil often providing a higher degree of intensification than the front foil. Foil quality is mainly defined by the intensification factor, quality on its part is characterized by the modulation transmission function and by the particle structure of the luminescent layer. Quality indicators are also the durability of the foils and the steadiness of the crystal arrangement in the luminescent layer. The representation quality is deteriorated also by the irregular blackening of the roentgen film, resulting from the statistic fluctuations of the roentgen quantums, which are absorbed in the luminescent layer. This unfavourable feature, termed quantum noise, increases with decreasing irradiation intensity, with increasing film gradation, and with increasing sensivity of the film-foil-system. Moreover, an optimal image quality is only possible when film and foil are in good contact conditions (in the cassette).

  6. Bioactive endophytes warrant intensified exploration and conservation.

    Science.gov (United States)

    Smith, Stephen A; Tank, David C; Boulanger, Lori-Ann; Bascom-Slack, Carol A; Eisenman, Kaury; Kingery, David; Babbs, Beatrice; Fenn, Kathleen; Greene, Joshua S; Hann, Bradley D; Keehner, Jocelyn; Kelley-Swift, Elizabeth G; Kembaiyan, Vivek; Lee, Sun Jin; Li, Puyao; Light, David Y; Lin, Emily H; Ma, Cong; Moore, Emily; Schorn, Michelle A; Vekhter, Daniel; Nunez, Percy V; Strobel, Gary A; Donoghue, Michael J; Strobel, Scott A

    2008-08-25

    A key argument in favor of conserving biodiversity is that as yet undiscovered biodiversity will yield products of great use to humans. However, the link between undiscovered biodiversity and useful products is largely conjectural. Here we provide direct evidence from bioassays of endophytes isolated from tropical plants and bioinformatic analyses that novel biology will indeed yield novel chemistry of potential value. We isolated and cultured 135 endophytic fungi and bacteria from plants collected in Peru. nrDNAs were compared to samples deposited in GenBank to ascertain the genetic novelty of cultured specimens. Ten endophytes were found to be as much as 15-30% different than any sequence in GenBank. Phylogenetic trees, using the most similar sequences in GenBank, were constructed for each endophyte to measure phylogenetic distance. Assays were also conducted on each cultured endophyte to record bioactivity, of which 65 were found to be bioactive. The novelty of our contribution is that we have combined bioinformatic analyses that document the diversity found in environmental samples with culturing and bioassays. These results highlight the hidden hyperdiversity of endophytic fungi and the urgent need to explore and conserve hidden microbial diversity. This study also showcases how undergraduate students can obtain data of great scientific significance.

  7. Bioactive endophytes warrant intensified exploration and conservation.

    Directory of Open Access Journals (Sweden)

    Stephen A Smith

    2008-08-01

    Full Text Available A key argument in favor of conserving biodiversity is that as yet undiscovered biodiversity will yield products of great use to humans. However, the link between undiscovered biodiversity and useful products is largely conjectural. Here we provide direct evidence from bioassays of endophytes isolated from tropical plants and bioinformatic analyses that novel biology will indeed yield novel chemistry of potential value.We isolated and cultured 135 endophytic fungi and bacteria from plants collected in Peru. nrDNAs were compared to samples deposited in GenBank to ascertain the genetic novelty of cultured specimens. Ten endophytes were found to be as much as 15-30% different than any sequence in GenBank. Phylogenetic trees, using the most similar sequences in GenBank, were constructed for each endophyte to measure phylogenetic distance. Assays were also conducted on each cultured endophyte to record bioactivity, of which 65 were found to be bioactive.The novelty of our contribution is that we have combined bioinformatic analyses that document the diversity found in environmental samples with culturing and bioassays. These results highlight the hidden hyperdiversity of endophytic fungi and the urgent need to explore and conserve hidden microbial diversity. This study also showcases how undergraduate students can obtain data of great scientific significance.

  8. Baltic air wars intensify / Dorian Ziedonis

    Index Scriptorium Estoniae

    Ziedonis, Dorian

    2008-01-01

    Leedu lennufirma FlyLAL pidi maksma ära 40 000 euro suuruse trahvi, et firma lennuk saaks Riia lennuväljalt lahkuda. Varem oli FlyLAL nõudnud Riia Lennujaamalt kompensatsiooni, kuna lennujaam oli võimaldanud Läti lennufirmal airBaltic maksta väiksemaid lennujaamatasusid

  9. Trolling may intensify exploitation in crappie fisheries

    Science.gov (United States)

    Meals, K. O.; Dunn, A. W.; Miranda, Leandro E.

    2012-01-01

    In some parts of the USA, anglers targeting crappies Pomoxis spp. are transitioning from mostly stationary angling with a single pole around submerged structures to using multiple poles while drifting with the wind or under power. This shift in fishing methods could result in a change in catch efficiency, possibly increasing exploitation rates to levels that would be of concern to managers. We studied the catch statistics of anglers fishing while trolling with multiple poles (trollers) and those fishing with single poles (polers) in Mississippi reservoirs. Specifically, we tested whether (1) various catch statistics differed between trollers and polers, (2) catch rates of trollers were related to the number of poles fished, and (3) trollers could raise exploitation rates to potentially unsustainable levels. Results showed that participation in the crappie fisheries was about equally split between polers and trollers. In spring, 90% of crappie anglers were polers; in summer, 85% of crappie anglers were trollers. The size of harvested crappies was similar for the two angler groups, but the catch per hour was almost three times higher for trollers than for polers. Catch rates by trollers were directly correlated to the number of poles fished, although the relationship flattened as the number of poles increased. The average harvest rate for one troller fishing with three poles was similar to the harvest rate obtained by one poler. Simulations predicted that at the existing mix of about 50% polers and 50% trollers and with no restrictions on the number of poles used by trollers, exploitation of crappies is about 1.3 times higher than that in a polers-only fishery; under a scenario in which 100% of crappie anglers were trollers, exploitation was forecasted to increase to about 1.7 times the polers-only rate. The efficiency of trolling for crappies should be of concern to fishery managers because crappie fisheries are mostly consumptive and may increase exploitation rates to unsustainable levels.

  10. Vacuum casing for radiologic image intensifier tube

    International Nuclear Information System (INIS)

    Colomb, G.; Verat, M.

    1986-01-01

    This envelope includes a window, related to an iron alloyed central body, realized in aluminium and magnesium alloy. This window is let in an aluminium body and welded. The aluminium body is brazed by brazed joint at aluminium-silicium or aluminium-silicium-magnesium eutectic to the central body [fr

  11. Effect of intensifying screens to subject contrast

    International Nuclear Information System (INIS)

    Lee, In Ja; Huh, Joon; Kang, Hong Seok; Yoon, Chul Ho

    1990-01-01

    It is an experimental report about object contrast according to the Kinds of screen and obtained results as follows ; 1. In the same object radiography, use acquired the difference of the object contrast between LT-II(CaWO 4 system) and G4(Gd system) screens. 2. object contrast more decreased in Gd system screen than CaWO 4 and object contrast controlled by X-ray tube voltage. 3. The difference of object contrast seen clearly in 80 kVp

  12. Mammography with rare earth intensifying screens

    International Nuclear Information System (INIS)

    Maurer, H.J.; Goos, F.

    1987-01-01

    Screens basing on rare earth phosphors with suitable films green or blue sensitive may be used in mammography with grids without diagnostic losses. Highest definition will be obtained with medium densities on film. High-speed screens may reduce dose, but definition is poor. Best compromise between speed and high definition may be reached with relative low thickness of phosphor layers. A system of high definition films (Medichrome) and special rare earth screens give best results. (orig.) [de

  13. New pasture plants intensify invasive species risk.

    Science.gov (United States)

    Driscoll, Don A; Catford, Jane A; Barney, Jacob N; Hulme, Philip E; Inderjit; Martin, Tara G; Pauchard, Aníbal; Pyšek, Petr; Richardson, David M; Riley, Sophie; Visser, Vernon

    2014-11-18

    Agricultural intensification is critical to meet global food demand, but intensification threatens native species and degrades ecosystems. Sustainable intensification (SI) is heralded as a new approach for enabling growth in agriculture while minimizing environmental impacts. However, the SI literature has overlooked a major environmental risk. Using data from eight countries on six continents, we show that few governments regulate conventionally bred pasture taxa to limit threats to natural areas, even though most agribusinesses promote taxa with substantial weed risk. New pasture taxa (including species, subspecies, varieties, cultivars, and plant-endophyte combinations) are bred with characteristics typical of invasive species and environmental weeds. By introducing novel genetic and endophyte variation, pasture taxa are imbued with additional capacity for invasion and environmental impact. New strategies to prevent future problems are urgently needed. We highlight opportunities for researchers, agribusiness, and consumers to reduce environmental risks associated with new pasture taxa. We also emphasize four main approaches that governments could consider as they build new policies to limit weed risks, including (i) national lists of taxa that are prohibited based on environmental risk; (ii) a weed risk assessment for all new taxa; (iii) a program to rapidly detect and control new taxa that invade natural areas; and (iv) the polluter-pays principle, so that if a taxon becomes an environmental weed, industry pays for its management. There is mounting pressure to increase livestock production. With foresight and planning, growth in agriculture can be achieved sustainably provided that the scope of SI expands to encompass environmental weed risks.

  14. A taxonomy of control in intensified processes

    International Nuclear Information System (INIS)

    Barzin, R.; Abd Shukor, S.R.; Ahmad, A.L.

    2006-01-01

    Process Intensification (PI) is a revolutionary approach to design, development and implementation of process and plant. PI technology offers improved environment in a chemical process in terms of better products, and processes which are safer, cleaner, smaller - and cheaper. PI is a strategy of making dramatic reductions in the size of unit operations within chemical plants, in order to achieve given production objectives. However, PI technology would be handicapped if such system is not properly controlled. There are some foreseeable problems in order to control such processes for instance, dynamic interaction between components that make up a control loop, response time of the instrumentations, availability of proper sensor and etc. In some cases, in order to control these systems, advanced control solutions have been applied i.e. model predictive controllers (MPC) and its different algorithms such as quadratic generalized predictive control (QGPC) and self tuning quadratic generalized predictive control (STQGPC). Nevertheless in some cases simpler solutions could be applied to control such system for example proportional integral controller in the control of reactive distillation systems. As mentioned, conventional control systems like proportional-integral, proportional-integral-derivative (PID) controllers and their different structures can be used in PI systems but due to inherent nonlinearity and fast responsiveness of PI systems, digital controllers-regarding to their robustness-are mostly applied in order to control PI systems. Regarding to the fact that choosing the appropriate control strategy is the most essential part of making PI systems possible to be handle easily, taxonomy of the usage of various control structure in controlling PI systems is proposed. This paper offers an overview and discussion on identifying potential problems of instrumentation in PI technology and available control strategies

  15. Charge coupled devices vs. microchannel plates in the extreme and far ultraviolet - A comparison based on the latest laboratory measurements

    Science.gov (United States)

    Vallerga, J.; Lampton, M.

    1988-01-01

    While microchannel plates (MCPs) have been established as imaging photon counters in the EUV and FUV for some years, CCDs are associated with low light level sensing at visible and near-IR wavelengths. Attention is presently given to recent proposals for CCDs' use as EUV and FUV detectors with quantum efficiencies sometimes exceeding those of MCPs; quantum resolution, format size, dynamic range, and long-term stability are also used as bases of comparison, for the cases of both space-based astronomical and spectroscopic applications.

  16. Optical studies of X-ray sources with the MASCOT - a charge-coupled device /CCD/-based astronomical instrument

    International Nuclear Information System (INIS)

    Ricker, G.R.; Bautz, M.W.; Dewey, D.; Meyer, S.S.

    1981-01-01

    The performance levels achieved by the MASCOT (MIT Astronomical Spectrometer/Camera for Optical Telescopes) on the 1.3-m telescope at the McGraw-Hill observatory in March 1981 are discussed along with preliminary data obtained in searches for optical counterparts to four 'empty-field' X-ray sources. In the W band (4000-7000 A), the MASCOT achieved a sky-limited sensitivity of +24.4 mag per sq arcsec in an 1800 s integration. The ability to flatten pictures to a level consistent with (sky + source) photon statistics and readout noise was demonstrated. For the four sources observed, an optical counterpart was established for one source (1413+13) based on positional coincidence (better than 1.8 arcsec), four possible candidates were detected in the error box of another source (1009 35) and upper sensitivity limits were established for optical counterparts in the error boxes for the other two sources (0920+39 and 0931-11)

  17. CHARGE-COUPLED DEVICE SPECKLE OBSERVATIONS OF BINARY STARS WITH THE WIYN TELESCOPE. V. MEASURES DURING 2001-2006

    International Nuclear Information System (INIS)

    Horch, Elliott P.; Van Altena, William F.; Cyr, William M. Jr; Kinsman-Smith, Lori; Srivastava, Amit; Zhou Jing

    2008-01-01

    A total of 1067 speckle observations of 345 binary stars are presented. Of these, 161 are double stars first resolved by Hipparcos, 17 are resolved for the first time in the observations presented here, and 21 are stars previously discovered by our program and reported in earlier papers in the series. In 947 cases, a magnitude difference is reported along with the relative astrometry. When comparing to systems with very well-known orbits, we find that the root mean square (rms) deviation in separation residuals is 2.81 ± 0.28 mas, and the rms deviation in position angle residuals is 0.88 ± 0.07 0 . The magnitude difference measures show no significant deviation from Hipparcos photometry, and have average standard deviation of approximately 0.10 mag as judged from repeat observations. Five important systems discovered by Hipparcos are discussed.

  18. Modulation transfer function and detective quantum efficiency of electron bombarded charge coupled device detector for low energy electrons

    Czech Academy of Sciences Publication Activity Database

    Horáček, Miroslav

    2005-01-01

    Roč. 76, č. 9 (2005), 093704:1-6 ISSN 0034-6748 R&D Projects: GA ČR(CZ) GA202/03/1575 Keywords : electron bombarded CCD * modulation transfer function * detective quantum efficiency Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 1.235, year: 2005

  19. Comparison between radiation exposure levels using an image intensifier and a flat-panel detector-based system in image-guided central venous catheter placement in children weighing less than 10 kg

    Energy Technology Data Exchange (ETDEWEB)

    Miraglia, Roberto; Maruzzelli, Luigi; Cortis, Kelvin; Gerasia, Roberta; Maggio, Simona; Luca, Angelo [Diagnostic and Therapeutic Services, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT), Palermo (Italy); Piazza, Marcello [Department of Anesthesia, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT), Palermo (Italy); Tuzzolino, Fabio [Department of Information Technology, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT), Palermo (Italy)

    2014-09-10

    Ultrasound-guided central venous puncture and fluoroscopic guidance during central venous catheter (CVC) positioning optimizes technical success and lowers the complication rates in children, and is therefore considered standard practice. The purpose of this study was to compare the radiation exposure levels recorded during CVC placement in children weighing less than 10 kg in procedures performed using an image intensifier-based angiographic system (IIDS) to those performed in a flat-panel detector-based interventional suite (FPDS). A retrospective review of 96 image-guided CVC placements, between January 2008 and October 2013, in 49 children weighing less than 10 kg was performed. Mean age was 8.2 ± 4.4 months (range: 1-22 months). Mean weight was 7.1 ± 2.7 kg (range: 2.5-9.8 kg). The procedures were classified into two categories: non-tunneled and tunneled CVC placement. Thirty-five procedures were performed with the IIDS (21 non-tunneled CVC, 14 tunneled CVC); 61 procedures were performed with the FPDS (47 non-tunneled CVC, 14 tunneled CVC). For non-tunneled CVC, mean DAP was 113.5 ± 126.7 cGy cm{sup 2} with the IIDS and 15.9 ± 44.6 cGy . cm{sup 2} with the FPDS (P < 0.001). For tunneled CVC, mean DAP was 84.6 ± 81.2 cGy . cm{sup 2} with the IIDS and 37.1 ± 33.5 cGy cm{sup 2} with the FPDS (P = 0.02). The use of flat-panel angiographic equipment reduces radiation exposure in small children undergoing image-guided CVC placement. (orig.)

  20. Socioeconomic benefit to individuals of achieving 2020 targets for four neglected tropical diseases controlled/eliminated by innovative and intensified disease management: Human African trypanosomiasis, leprosy, visceral leishmaniasis, Chagas disease.

    Science.gov (United States)

    Lenk, Edeltraud J; Redekop, William K; Luyendijk, Marianne; Fitzpatrick, Christopher; Niessen, Louis; Stolk, Wilma A; Tediosi, Fabrizio; Rijnsburger, Adriana J; Bakker, Roel; Hontelez, Jan A C; Richardus, Jan H; Jacobson, Julie; Le Rutte, Epke A; de Vlas, Sake J; Severens, Johan L

    2018-03-01

    The control or elimination of neglected tropical diseases (NTDs) has targets defined by the WHO for 2020, reinforced by the 2012 London Declaration. We estimated the economic impact to individuals of meeting these targets for human African trypanosomiasis, leprosy, visceral leishmaniasis and Chagas disease, NTDs controlled or eliminated by innovative and intensified disease management (IDM). A systematic literature review identified information on productivity loss and out-of-pocket payments (OPPs) related to these NTDs, which were combined with projections of the number of people suffering from each NTD, country and year for 2011-2020 and 2021-2030. The ideal scenario in which the WHO's 2020 targets are met was compared with a counterfactual scenario that assumed the situation of 1990 stayed unaltered. Economic benefit equaled the difference between the two scenarios. Values are reported in 2005 US$, purchasing power parity-adjusted, discounted at 3% per annum from 2010. Probabilistic sensitivity analyses were used to quantify the degree of uncertainty around the base-case impact estimate. The total global productivity gained for the four IDM-NTDs was I$ 23.1 (I$ 15.9 -I$ 34.0) billion in 2011-2020 and I$ 35.9 (I$ 25.0 -I$ 51.9) billion in 2021-2030 (2.5th and 97.5th percentiles in brackets), corresponding to US$ 10.7 billion (US$ 7.4 -US$ 15.7) and US$ 16.6 billion (US$ 11.6 -US$ 24.0). Reduction in OPPs was I$ 14 billion (US$ 6.7 billion) and I$ 18 billion (US$ 10.4 billion) for the same periods. We faced important limitations to our work, such as finding no OPPs for leprosy. We had to combine limited data from various sources, heterogeneous background, and of variable quality. Nevertheless, based on conservative assumptions and subsequent uncertainty analyses, we estimate that the benefits of achieving the targets are considerable. Under plausible scenarios, the economic benefits far exceed the necessary investments by endemic country governments and their

  1. Laser-Induced Fluorescence and Synthetic Jet Fuel Analysis in the Ultra Compact Combustor

    Science.gov (United States)

    2009-12-01

    Performance Turbine Engine Technology ICCD Intensifying Charge Couple Device IGV Inlet guide vanes ISSI Innovative Scientific Solutions Inc. ITB...centerbody in Fig. 5 simulate inlet guide vanes ( IGV ) or stator blades. In each airfoil, there is a radial vane cavity (RVC) establishing an intermediate

  2. Measurements of plasma temperature and electron density in laser

    Indian Academy of Sciences (India)

    The temperature and electron density characterizing the plasma are measured by time-resolved spectroscopy of neutral atom and ion line emissions in the time window of 300–2000 ns. An echelle spectrograph coupled with a gated intensified charge coupled detector is used to record the plasma emissions.

  3. Branching of positive discharge streamers in air at varying pressures

    NARCIS (Netherlands)

    Briels, T.M.P.; Veldhuizen, van E.M.; Ebert, U.M.

    2005-01-01

    The formation of positive streamers in a 17-mm gap in air is studied at pressures varying in the range from 1010 to 100 mbar. An intensified charge coupled device camera is used to image the discharge. At high pressures, the discharge shows many branches, while at low pressure, fewer branches arise.

  4. Readout of the UFFO Slewing Mirror Telescope to detect UV/optical photons from Gamma-Ray Bursts

    DEFF Research Database (Denmark)

    Kim, J. E.; Lim, H.; Nam, J. W.

    2013-01-01

    plane detector of Intensified Charge-Coupled Device (ICCD). The ICCD is sensitive to UV/optical photons of 200–650 nm in wavelength by using a UV-enhanced S20 photocathode and amplifies photoelectrons at a gain of 104–106 in double Micro-Channel Plates. These photons are read out by a Kodak KAI-0340...

  5. Effects of an intensified production adjustment to the biomass production in the operational sequence of agricultural enterprises on ecological and economic indices. Results of modellings in practical operations; Auswirkungen einer verstaerkten Produktionsausrichtung zur Biomasseerzeugung im Betriebsablauf landwirtschaftlicher Unternehmen auf oekologische und oekonomische Kennziffern. Ergebnisse von Modellierungen in Praxisbetrieben

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Bernhard; Reinicke, Frank

    2008-07-01

    The supply of biomass for the power generated is the centre of the contribution under consideration. Authoritative is the sustainable organization of the production in the cultivation of the energy crops and in the entire operating system. At first, the actual situation in selected operating systems is described due to the data of the last three years. From this, scenarios are derived in which the crop rotations are accomplished application specific and with consideration of the natural local conditions on an intensified production of bio sources of energy. Likewise, aspects of specifically changed nutrient flows and energy flows are pointed out such as the intensities in plant protection, the erosion danger and effects on the bio diversity. Only on basis of application specific analyses, the sustainability of production can be improved. Regional cultivation concentrations for energy crops are conceivable. However the borders of the cultivation of energy plant primarily depend on the economic characteristic numbers of individual companies.

  6. Visual Enhancement of Laparoscopic Partial Nephrectomy With 3-Charge Coupled Device Camera: Assessing Intraoperative Tissue Perfusion and Vascular Anatomy by Visible Hemoglobin Spectral Response

    Science.gov (United States)

    2010-10-01

    reliably distinguish vascular structures during hilar dissection, and detect and monitor changes in renal tissue perfus:ion dw·ing and after warm...and in 25 patients with hilar tu- mors 16 in whom perioperative outcomes were com- parable to those of peripheral tumors. In a retro- spective study...Richstone et al also reported the safe performance of LPN for hilar tumors in 17 patients.17 Repeat partial nephrectomy for ipsilat- eral tumor has

  7. Electron Transport in a Dioxygenase-Ferredoxin Complex: Long Range Charge Coupling between the Rieske and Non-Heme Iron Center.

    Directory of Open Access Journals (Sweden)

    Wayne K Dawson

    Full Text Available Dioxygenase (dOx utilizes stereospecific oxidation on aromatic molecules; consequently, dOx has potential applications in bioremediation and stereospecific oxidation synthesis. The reactive components of dOx comprise a Rieske structure Cys2[2Fe-2S]His2 and a non-heme reactive oxygen center (ROC. Between the Rieske structure and the ROC, a universally conserved Asp residue appears to bridge the two structures forming a Rieske-Asp-ROC triad, where the Asp is known to be essential for electron transfer processes. The Rieske and ROC share hydrogen bonds with Asp through their His ligands; suggesting an ideal network for electron transfer via the carboxyl side chain of Asp. Associated with the dOx is an itinerant charge carrying protein Ferredoxin (Fdx. Depending on the specific cognate, Fdx may also possess either the Rieske structure or a related structure known as 4-Cys-[2Fe-2S] (4-Cys. In this study, we extensively explore, at different levels of theory, the behavior of the individual components (Rieske and ROC and their interaction together via the Asp using a variety of density function methods, basis sets, and a method known as Generalized Ionic Fragment Approach (GIFA that permits setting up spin configurations manually. We also report results on the 4-Cys structure for comparison. The individual optimized structures are compared with observed spectroscopic data from the Rieske, 4-Cys and ROC structures (where information is available. The separate pieces are then combined together into a large Rieske-Asp-ROC (donor/bridge/acceptor complex to estimate the overall coupling between individual components, based on changes to the partial charges. The results suggest that the partial charges are significantly altered when Asp bridges the Rieske and the ROC; hence, long range coupling through hydrogen bonding effects via the intercalated Asp bridge can drastically affect the partial charge distributions compared to the individual isolated structures. The results are consistent with a proton coupled electron transfer mechanism.

  8. Green Grape Detection and Picking-Point Calculation in a Night-Time Natural Environment Using a Charge-Coupled Device (CCD Vision Sensor with Artificial Illumination

    Directory of Open Access Journals (Sweden)

    Juntao Xiong

    2018-03-01

    Full Text Available Night-time fruit-picking technology is important to picking robots. This paper proposes a method of night-time detection and picking-point positioning for green grape-picking robots to solve the difficult problem of green grape detection and picking in night-time conditions with artificial lighting systems. Taking a representative green grape named Centennial Seedless as the research object, daytime and night-time grape images were captured by a custom-designed visual system. Detection was conducted employing the following steps: (1 The RGB (red, green and blue. Color model was determined for night-time green grape detection through analysis of color features of grape images under daytime natural light and night-time artificial lighting. The R component of the RGB color model was rotated and the image resolution was compressed; (2 The improved Chan–Vese (C–V level set model and morphological processing method were used to remove the background of the image, leaving out the grape fruit; (3 Based on the character of grape vertical suspension, combining the principle of the minimum circumscribed rectangle of fruit and the Hough straight line detection method, straight-line fitting for the fruit stem was conducted and the picking point was calculated using the stem with an angle of fitting line and vertical line less than 15°. The visual detection experiment results showed that the accuracy of grape fruit detection was 91.67% and the average running time of the proposed algorithm was 0.46 s. The picking-point calculation experiment results showed that the highest accuracy for the picking-point calculation was 92.5%, while the lowest was 80%. The results demonstrate that the proposed method of night-time green grape detection and picking-point calculation can provide technical support to the grape-picking robots.

  9. A Synthesis of Star Calibration Techniques for Ground-Based Narrowband Electron-Multiplying Charge-Coupled Device Imagers Used in Auroral Photometry

    Science.gov (United States)

    Grubbs, Guy II; Michell, Robert; Samara, Marilia; Hampton, Don; Jahn, Jorg-Micha

    2016-01-01

    A technique is presented for the periodic and systematic calibration of ground-based optical imagers. It is important to have a common system of units (Rayleighs or photon flux) for cross comparison as well as self-comparison over time. With the advancement in technology, the sensitivity of these imagers has improved so that stars can be used for more precise calibration. Background subtraction, flat fielding, star mapping, and other common techniques are combined in deriving a calibration technique appropriate for a variety of ground-based imager installations. Spectral (4278, 5577, and 8446 A ) ground-based imager data with multiple fields of view (19, 47, and 180 deg) are processed and calibrated using the techniques developed. The calibration techniques applied result in intensity measurements in agreement between different imagers using identical spectral filtering, and the intensity at each wavelength observed is within the expected range of auroral measurements. The application of these star calibration techniques, which convert raw imager counts into units of photon flux, makes it possible to do quantitative photometry. The computed photon fluxes, in units of Rayleighs, can be used for the absolute photometry between instruments or as input parameters for auroral electron transport models.

  10. Measurement of the modulation transfer function of a charge-coupled device array by the combination of the self-imaging effect and slanted edge method.

    Science.gov (United States)

    Najafi, Sedigheh; Madanipour, Khosro

    2013-07-01

    In this paper, by a combination of the self-imaging effect for Ronchi gratings and the standard slanted edge modulation transfer function (MTF) measurement method for CCD cameras, the MTF of the CCD array without optics is measured. For this purpose, a Ronchi-type grating is illuminated by an expanded He-Ne laser. A self-image of the grating appears without optics on the CCD array that is located on the Talbot distance. The lines of the self-image of the grating are used as a slanted edge array. This method has all the advantages of the slanted edge method, and also since the array of the edge is ready, the total area of the CCD can be tested. The measured MTF is related to the CCD array without optics.

  11. Two dimensional CCD [charged coupled device] arrays as parallel detectors in electron energy loss and x-ray wavelength dispersive spectroscopy

    International Nuclear Information System (INIS)

    Zaluzec, N.J.

    1988-08-01

    Parallel detection systems for spectroscopy have generally been based upon linear detector arrays. Replacing the linear arrays with two dimensional systems yields more complicated devices; however, there are corresponding benefits which can be realized for both x-ray and electron energy loss spectroscopy. The operational design of these systems, as well as preliminary results from the construction of such a device used for electron spectroscopy, are presented. 10 refs., 8 figs

  12. Reduced river discharge intensifies phytoplankton bloom in Godavari estuary, India

    Digital Repository Service at National Institute of Oceanography (India)

    Acharyya, T.; Sarma, V.V.S.S.; Sridevi, B.; Venkataramana, V.; Bharathi, M.D.; Naidu, S.A.; Kumar, B.S.K.; Prasad, V.R.; Bandyopadhyay, D.; Reddy, N.P.C.; DileepKumar, M.

    et al., 2009; Sarma et al., 2011), behaviour of different 3 elements (Sarma et al., 1993) and heavy metals (Somayajulu et al., 1993).Virtually no systematic studies have been undertaken so far in these estuaries focussing on spatial and... their class specific marker pigment fucoxanthin (Jeffry et al., 1997; Mantoura and Llewellyn, 1983; Wright et al., 1991). To confirm the influence of SPM and flushing time on phytoplankton bloom a laboratory- based incubation experiment was conducted...

  13. Intensifying drying process with creation of functional plant compositions

    Directory of Open Access Journals (Sweden)

    Zh. Petrova

    2015-05-01

    Full Text Available Introduction. The process of drying agricultural raw products is associated with loss of bioactive substances by the products exposed to heat, light, oxygen, or рН medium. It is reasonable to enhance the table beet processing technology in order to achieve maximum betanin conservation at lower energy consumption. Materials and methods. Table beets, rhubarbs, lemons, and tomatoes were dried at temperature of 50 to 100 ºС, air speed of 1.5 to 3.5 m/s, heat carrier water content of 7 to 15 g/kg, and layer thickness of 2 to 20 mm. The betanіn content was determined via absorption spectra, using the optical density value at 540 nm wavelength. A differential microcalorimeter was used for measuring evaporation heat consumption. Results and discussion.The effect of raw product pre-drying preparation was studied. With no preliminary preparation, the loss of betanin after drying reaches 66 %. The preliminary preparation technology we have developed includes boiling whole root crops with optimal selection of acid medium and allows us to reduce the betanin loss down to 6 %. Regretfully, the process requires large energy consumption. Low energy consumption pre-drying preparation method was developed for antioxidant raw products with thermal processing replaced by blending. The betanin loss, in this case, does not exceed 5 %. Optimal drying temperature of betanin-containing raw stock, after its preliminary processing, is 60 °С. It allows to keep up to 95 % of betanіn. Specific heat consumption for water evaporation out of the developed table beet based antioxidant plant compositions, with addition of rhubarb and lemon, is less by 4 to 5 % as compared to the initial components. Conclusions. Dependence of betanin loss in plant raw stock on the material temperature and composition components, in the course of their pre-drying preparation, was found. It was also found that water evaporation heat, for some antioxidant plant compositions developed, is less as compared to the initial raw stock components. It is reasonable to use the results for development of industrial thermal processing technologies used for functional food powder production.

  14. Balanced thermal structure of an intensifying tropical cyclone

    Directory of Open Access Journals (Sweden)

    David J. Raymond

    2012-12-01

    Full Text Available This study tests the hypothesis that the formation of a virtual potential temperature dipole in a developing tropical cyclone is a balanced response to the growth of an associated mid-level vortex. The dipole is collocated with the vortex and consists of a warm anomaly in the upper troposphere and a cool anomaly in the lower troposphere. An axisymmetric approximation to the observed potential vorticity distribution is inverted subject to non-linear balance for two successive days during the formation of typhoon Nuri in 2008. Good agreement is found between the area-averaged actual and balanced virtual temperature dipoles in these two cases. Furthermore, a strong correlation exists between the degree of bottom-heaviness of convective mass flux profiles and the strength of the balanced virtual potential temperature dipole. Since the dipole is balanced, it cannot be an immediate artefact of the existing convection, but rather is an inherent feature of the developing cyclone. Cloud resolving numerical modelling suggests that the dipole temperature anomaly actually promotes more bottom-heavy convective mass flux profiles, as observed. Such profiles are associated with low-level mass and vorticity convergence via mass continuity and the circulation theorem, resulting in low-level spin-up. The present work thus supports the hypothesis that the low-level spin-up associated with tropical cyclogenesis is made possible by the thermodynamic environment created by a strong mid-level vortex.

  15. Intensifying Innovation Adoption in Educational eHealth

    Science.gov (United States)

    Rissanen, M. K.

    2014-01-01

    In demanding innovation areas such as eHealth, the primary emphasis is easily placed on the product and process quality aspects in the design phase. Customer quality may receive adequate attention when the target audience is well-defined. But if the multidimensional evaluative focus does not get enough space until the implementation phase, this…

  16. Connected languages : Effects of intensifying contact between Turkish and Dutch

    NARCIS (Netherlands)

    Demirçay, Derya

    2017-01-01

    In today’s globalized world movement of people, information and knowledge is made easier each passing day. Thus, isolated, monolingual communities are rare in the modern world. This dissertation looks into bilinguals’ use of their languages within the community of Turkish-Dutch speakers in the

  17. Optimal hybrid separations for intensified downstream processing of biobutanol

    NARCIS (Netherlands)

    Sánchez-Ramírez, Eduardo; Quiroz-Ramírez, Juan José; Hernández, Salvador; Segovia-Hernández, Juan Gabriel; Kiss, Anton A.

    2017-01-01

    Current research focuses on new energy alternatives which could compete with the traditional energy sources based on fossil fuels, and eventually diminish the consequences on climate. Recently, butanol produced by ABE fermentation attracted more attention since its energy power is comparable to that

  18. Sustainable Intensified Process Retrofit for the Production of MDI

    DEFF Research Database (Denmark)

    Babi, Deenesh Kavi; Woodley, John; Gani, Rafiqul

    Process intensification (PI) is a means by which processes can be made more efficient and sustainable at different levels, the unit operations, functional and phenomena levels. Therefore PI can be used for making process improvements at the functional level for the production of an important poly...... polyurethane, methylene diphenyldi-isocyanate (MDI)....

  19. Home management of childhood diarrhoea: Need to intensify ...

    African Journals Online (AJOL)

    A review of home management of childhood diarrhea in under-five children among 203 Nigerian mothers was carried out over a period of 3 months in order to ascertain how effectively they manage their children with diarrhea outside a hospital setup (infrastructural health facility). Mothers whose children had diarrhea, with ...

  20. Will open ocean oxygen stress intensify under climate change?

    OpenAIRE

    A. Gnanadesikan; J. P. Dunne; J. John

    2011-01-01

    Global warming is expected to reduce oxygen solubility and vertical exchange in the ocean, changes which would be expected to result in an increase in the volume of hypoxic waters. A simulation made with a full earth system model with dynamical atmosphere, ocean, sea ice and biogeochemical cycling shows that this holds true if the condition for hypoxia is set relatively high. However, the volume of the most hypoxic waters does not increase under global warming, as these waters actually become...

  1. Will open ocean oxygen stress intensify under climate change?

    Science.gov (United States)

    Gnanadesikan, A.; Dunne, J. P.; John, J.

    2011-07-01

    Global warming is expected to reduce oxygen solubility and vertical exchange in the ocean, changes which would be expected to result in an increase in the volume of hypoxic waters. A simulation made with a full earth system model with dynamical atmosphere, ocean, sea ice and biogeochemical cycling shows that this holds true if the condition for hypoxia is set relatively high. However, the volume of the most hypoxic waters does not increase under global warming, as these waters actually become more oxygenated. We show that the rise in oxygen is associated with a drop in ventilation time. A term-by-term analysis within the least oxygenated waters shows an increased supply of oxygen due to lateral diffusion. compensating an increase in remineralization within these highly hypoxic waters. This lateral diffusive flux is the result of an increase of ventilation along the Chilean coast, as a drying of the region under global warming opens up a region of wintertime convection in our model.

  2. Madagascar's future climate change intensified actions and policy ...

    African Journals Online (AJOL)

    ... actions and policy reforms: fostering local initiatives or business as usual? ... policies in Madagascar, and suggest that there may be fundamental flaws in ... However, World Bank statistics show that, in current terms, Madagascar was ...

  3. The Threat Among Us: Insiders Intensify Aviation Terrorism

    Energy Technology Data Exchange (ETDEWEB)

    Krull, Katie E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-08-19

    Aviation terrorism is powerful and symbolic, and will likely remain a staple target for terrorists aiming to inflict chaos and cause mass casualties similar to the 9/11 attacks on the U.S. The majority of international and domestic aviation terrorist attacks involves outsiders, or people who do not have direct access to or affiliation with a target through employment. However, several significant attacks and plots against the industry involved malicious employees motivated by suicide or devotion to a terrorist organization. Malicious insiders’ access and knowledge of aviation security, systems, networks, and infrastructure is valuable to terrorists, providing a different pathway for attacking the industry through the insider threat. Indicators and warnings of insider threats in these cases exist, providing insight into how security agencies, such as the Transportation Security Administration, can better predict and identify insider involvement. Understanding previous aviation insider threat events will likely aid in stimulating proactive security measures, rather than reactive responses. However, similar to traditional airport security measures, there are social, political, and economic challenges in protecting against the insider threat, including privacy concerns and cost-benefit analysis.

  4. Intensified Pozzolanic Reaction on Kaolinite Clay-Based Mortar

    Directory of Open Access Journals (Sweden)

    Yang-Hee Kwon

    2017-05-01

    Full Text Available The objective of this study is to develop and characterize kaolinite clay-based structural mortar. The pozzolanic reaction induced from two mineral additives, i.e., calcium hydroxide and silica fume (SF, and the physical filling effect from SF, were found to be effective on the enhancement of structural properties. Based on several preliminary experiments, 7:3 ratio of kaolinite clay/calcium hydroxide was selected as a basic binder. Then, the amount of SF was chosen as 0%, 7.5%, and 15% of the total binder to consider both the chemical and physical effects. The results showed that compressive strengths of samples with 7.5% and 15% SF are significantly increased by approximately 200% and 350%, respectively, at 28 days compared to the sample without SF. However, based on the results of the sample with 15% SF, it is found that excessive addition of SF causes long-term strength loss, possibly owing to micro cracks. With the careful consideration on this long-term behavior, this suggested new mix design can be further extended to develop sustainable structural materials using natural minerals or waste materials with nonbinding properties.

  5. Contributions of roots and rootstocks to sustainable, intensified crop production.

    Science.gov (United States)

    Gregory, Peter J; Atkinson, Christopher J; Bengough, A Glyn; Else, Mark A; Fernández-Fernández, Felicidad; Harrison, Richard J; Schmidt, Sonja

    2013-03-01

    Sustainable intensification is seen as the main route for meeting the world's increasing demands for food and fibre. As demands mount for greater efficiency in the use of resources to achieve this goal, so the focus on roots and rootstocks and their role in acquiring water and nutrients, and overcoming pests and pathogens, is increasing. The purpose of this review is to explore some of the ways in which understanding root systems and their interactions with soils could contribute to the development of more sustainable systems of intensive production. Physical interactions with soil particles limit root growth if soils are dense, but root-soil contact is essential for optimal growth and uptake of water and nutrients. X-ray microtomography demonstrated that maize roots elongated more rapidly with increasing root-soil contact, as long as mechanical impedance was not limiting root elongation, while lupin was less sensitive to changes in root-soil contact. In addition to selecting for root architecture and rhizosphere properties, the growth of many plants in cultivated systems is profoundly affected by selection of an appropriate rootstock. Several mechanisms for scion control by rootstocks have been suggested, but the causal signals are still uncertain and may differ between crop species. Linkage map locations for quantitative trait loci for disease resistance and other traits of interest in rootstock breeding are becoming available. Designing root systems and rootstocks for specific environments is becoming a feasible target.

  6. Observation of Intensified Lower Hybrid Noise in the Midlatitude Ionosphere

    Czech Academy of Sciences Publication Activity Database

    Parrot, M.; Santolík, Ondřej; Brochot, J.; Y.; Berthelier, J. J.

    2008-01-01

    Roč. 36, č. 4 (2008), s. 1164-1165 ISSN 0093-3813 Grant - others:CNRS/DREI(FR) PICS Grant 3725 Institutional research plan: CEZ:AV0Z30420517 Keywords : lower hybrid frequency * midlatitude ionosphere * DEMETER spacecraft Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.447, year: 2008 http://ieeexplore.ieee.org/xpl/articleDetails.jsp?reload=true&arnumber=4553722

  7. Detective quantum efficiency of medical x-ray image intensifiers

    CSIR Research Space (South Africa)

    Thirlwall, JT

    1998-11-01

    Full Text Available -energyphotons,thevariancesofstagesafterthe photoemitterhavenegligiblein?uenc eonthevalueofBand thesehavebeenomittedfromthecalculationsreportedhere. Ithasbeenpointedout,however,11 thatwithanintensex-ray input,theXRIIoutputsignalmayhavetobeattenuated,for examplewithanirisintheopticalcomponents....W.ArndtandD.J.Gilmore,J.Appl.Crystallogr.12,1~1979!. 9 M.Stanton,W.Phillips,Y.Li,andK.Kalata,J.Appl.Crystallogr.25, 638~1992!. 10 W.KuhlandJ.E.Schrijvers,Medicamundi22,6~1977!. 11 A.Makovski,MedicalImagingSystems~Prentice?Hall,Englewood Cliffs,NJ,1983!,p.87. 12 S...

  8. Method and equipment for image intensifying in xeroradiography

    International Nuclear Information System (INIS)

    Jeromin, L.S.

    1975-01-01

    The xeroradiography or xeromammography uses, e.g. in mammography, a xerographic plate with an electrostatic charge. This charge reproduces a latent image of the part of the body irradiated with X-ray or γ-radiations. It is rendered visible by contacting with electrically oppositely charged, finely powdered particles. In order to be able to reduce the dose of radiation applied and to guarantee a sufficient contrasting, the latent image is, however, at first only partly exposed to a reduced radiation dose. After contacting with powder, the xerographic plate of an aluminum base with lead coating and the sensitive layer of amorphous or glazed selenium, is intermediately exposed to light. The final development is again carried out using powdered particles which lie on a higher voltage than those of the first contacting. (DG/LH) [de

  9. Ways of intensifying the conventional chamber carbonization of hard coal

    Energy Technology Data Exchange (ETDEWEB)

    Pelagalli, M.

    1986-12-01

    The intensification measures are intended to reduce both the investment cost and the operating cost via an increased performance factor. Automation had good results both in coal blending and in process monitoring and control. Coal blending, compression, and partial briquetting extend the range of coking coals.

  10. Intensified coastal development in beach-nourishment zones

    Science.gov (United States)

    Lazarus, E.; Armstrong, S.; Limber, P. W.; Goldstein, E. B.; Ballinger, R.

    2016-12-01

    Population density, housing development, and property values in coastal counties along the U.S. Atlantic and Gulf Coasts continue to rise despite increasing hazard from storm impacts. Beach nourishment, a method for mitigating coastal storm damage or chronic erosion by deliberately replacing sand on an eroded beach, has been the leading form of coastal protection in the U.S. since the 1970s. However, investment in hazard protection can have the unintended consequence of encouraging development in places especially vulnerable to damage. To quantitatively compare development in nourishing and non-nourishing zones, we examine the parcel-scale housing stock of all shorefront single-family homes in the state of Florida. We find that houses in nourishing zones are significantly larger and more numerous than in non-nourishing zones. Florida represents both an advanced case of coastal risk and an exemplar of ubiquitous, fundamental challenges in coastal management. The predominance of larger homes in nourishing zones indicates a positive feedback between nourishment and development that is compounding coastal risk in zones already characterized by high vulnerability. We offer that this phenomenon represents a variant of Jevons' paradox, a theoretical argument from environmental economics in which more efficient use of a resource spurs an increase in its consumption. Here, we suggest reductions in coastal risk through hazard protection are ultimately offset or reversed by increased coastal development.

  11. Marginal costs for intensified energy-efficiency measures

    International Nuclear Information System (INIS)

    Jakob, J.; Jochem, E.; Christen, K.

    2002-01-01

    The costs and benefits of investments in measures designed to improve the energy efficiency of residential buildings (in particular investments in heat insulation) were calculated as a function of increasing energy efficiency for new and renovated buildings and for single-family homes and apartment buildings. These investments in measures to improve efficiency mostly involve with the building envelope and ventilation systems and aim to successively reduce the space-heating needs of the buildings. The measures range from present-day building and renovation methods through to the 'Minergie' and 'Passive House' ('Minergie-P' in Switzerland) standards for low and very-low energy consumption buildings. Cost-benefit ratios were determined for individual building components, individual building concepts and for the whole of Switzerland, using both the average-cost as well as the pure marginal-cost methods (energy-economics level). The collection of empirical data (especially on costs) was an integral and important part of the project. The marginal costs were then compared with the benefits arising from the costs for space heating that were avoided, and, using a few typical cases as examples, with the so-called co-benefits, which are to be implemented in part by private persons and companies. For their quantification, methods were developed and used in case studies; in addition, avoided external costs are also considered. The marginal costs were also calculated for periods of time in the future, whereby they were made dynamic, according to their share of innovation, using the learning-curve method (learning and scaling effects). As far as the findings are concerned, there can be no doubt that the potential to be opened up for increasing energy efficiency using heat insulation measures is high, both for renovations and new construction work. A large portion of this potential is already economically viable and even more so when the possible risks of energy price increases, associated benefits (business economics level), the external costs avoided, the benefits if induced innovation and increased export possibilities are also included. (author)

  12. Madagascar's future climate change intensified actions and policy ...

    African Journals Online (AJOL)

    or business as usual? Jean-Roger MercierI ... reduce its 2030 emissions by 64% compared to the 'Business As ..... tion of work in the global, climate-conscious digital economy. ... business models for the development and delivery of physical goods and services. The potential for deploying ICTs for innovative products ...

  13. Sectorial energy observatory: the concentration of the sector intensifies

    International Nuclear Information System (INIS)

    2000-01-01

    The 1998 energy market conjuncture was particularly bad for two main reasons: the collapse of oil prices and the recession of primary energy consumption. This situation occurred while the regulatory framework of markets was becoming overturned because of the forthcoming deregulation of the European power market (February 1999) and of the natural gas market (summer 2000). In this context, the energy actors have concentrated their efforts to the reinforcement of their positions using external growth operations. Apart from the concentration process, the actors of the energy sector have carried on with their strategic initiatives started these last years, internationalization being their main strategic goal. Europe is their favoured zone but they more and more lust after the USA: oil companies are placing their positions downstream of the gas industry file, while gas distributors are moving upstream. The financial performances of energy actors have been greatly lowered with a general decreasing turnover (negative price effect). They have kept some important financial latitude in order to maintain their concentration policy. Their targets will be probably the German, British and Spanish electricity and gas utilities. The electric power sector has been one of the main sectors concerned by external growth operations, but the natural gas industry should encounter a similar evolution since summer 2000. (J.S.)

  14. Optimal design of intensified processes for DME synthesis

    NARCIS (Netherlands)

    Bîldea, Costin Sorin; Győrgy, Romuald; Brunchi, Cristian C.; Kiss, Anton A.

    2017-01-01

    Dimethyl ether (DME) is widely used as green aerosol propellant, precursor to other organic compounds, or as a clean fuel for diesel engines or in combustion cells. The classic method for producing DME is by dehydration of methanol in a catalytic gas-phase reactor, and purification in a direct

  15. Ionic liquids, tuneable solvents for intensifying reactions and separations

    NARCIS (Netherlands)

    Meindersma, G.W.; Kuipers, N.J.M.; Haan, de A.B.

    2007-01-01

    An Ionic Liquid (IL), or a Room Temperature Ionic Liquid (RTIL), is commonly defined as a liquid entirely composed of ions, which is a fluid below 100 °C. Due to the fact that an ionic liquid is a salt, it has a negligible vapour pressure. Therefore, ionic liquids are not volatile at ambient process

  16. Optogenetic Central Amygdala Stimulation Intensifies and Narrows Motivation for Cocaine.

    Science.gov (United States)

    Warlow, Shelley M; Robinson, Mike J F; Berridge, Kent C

    2017-08-30

    Addiction is often characterized by intense motivation for a drug, which may be narrowly focused at the expense of other rewards. Here, we examined the role of amygdala-related circuitry in the amplification and narrowing of motivation focus for intravenous cocaine. We paired optogenetic channelrhodopsin (ChR2) stimulation in either central nucleus of amygdala (CeA) or basolateral amygdala (BLA) of female rats with one particular nose-poke porthole option for earning cocaine infusions (0.3 mg/kg, i.v.). A second alternative porthole earned identical cocaine but without ChR2 stimulation. Consequently, CeA rats quickly came to pursue their CeA ChR2-paired cocaine option intensely and exclusively, elevating cocaine intake while ignoring their alternative cocaine alone option. By comparison, BLA ChR2 pairing failed to enhance cocaine motivation. CeA rats also emitted consummatory bites toward their laser-paired porthole, suggesting that higher incentive salience made that cue more attractive. A separate progressive ratio test of incentive motivation confirmed that CeA ChR2 amplified rats' motivation, raising their breakpoint effort price for cocaine by 10-fold. However, CeA ChR2 laser on its own lacked any reinforcement value: laser by itself was never self-stimulated, not even by the same rats in which it amplified motivation for cocaine. Conversely, CeA inhibition by muscimol/baclofen microinjections prevented acquisition of cocaine self-administration and laser preference, whereas CeA inhibition by optogenetic halorhodopsin suppressed cocaine intake, indicating that CeA circuitry is needed for ordinary cocaine motivation. We conclude that CeA ChR2 excitation paired with a cocaine option specifically focuses and amplifies motivation to produce intense pursuit and consumption focused on that single target. SIGNIFICANCE STATEMENT In addiction, intense incentive motivation often becomes narrowly focused on a particular drug of abuse. Here we show that pairing central nucleus of amygdala (CeA) optogenetic stimulation with one option for earning intravenous cocaine makes that option almost the exclusive focus of intense pursuit and consumption. CeA stimulation also elevated the effort cost rats were willing to pay for cocaine and made associated cues become intensely attractive. However, we also show that CeA laser had no reinforcing properties at all when given alone for the same rats. Therefore, CeA laser pairing makes its associated cocaine option and cues become powerfully attractive in a nearly addictive fashion. Copyright © 2017 the authors 0270-6474/17/378330-19$15.00/0.

  17. Teachers' stress intensifies violent disciplining in Tanzanian secondary schools.

    Science.gov (United States)

    Hecker, Tobias; Goessmann, Katharina; Nkuba, Mabula; Hermenau, Katharin

    2018-02-01

    Violent forms of discipline in schools continue to be widespread across the globe despite their damaging effects. Since little is known about factors influencing the extent of violence applied by teachers, this study aimed to investigate the influence of teachers' stress, work satisfaction, and personal characteristics on their disciplining style. Using structural equation modeling, associations between violent discipline, burnout symptoms, and job perceptions (pressure and difficulties in class) reported by 222 teachers from 11 secondary schools in Tanzania in 2015 were analyzed. Results indicated a direct association between perceived stress and emotional violent discipline (β=.18, pjob perceptions and both forms of violent disciplining. The model showed good model fit (χ 2 [44, n=222]=67.47 (p=.013), CFI=.94, TLI=.91, IFI=.94, RMSEA=.049 [90%-CI=.02-.07, PCLOSE=.50], SRMR=.06). Our findings suggest that teachers' personal perceptions of their work as well as their stress burden play a role in their disciplining styles. Our findings underline the importance of integrating topics, such as stress and coping as well as positive, nonviolent discipline measures into the regular teacher's training and in addition to develop and evaluate school-based preventative interventions for teachers. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Alkalinity production in intertidal sands intensified by lugworm bioirrigation

    NARCIS (Netherlands)

    Rao, A.M.F.; Malkin, S.Y.; Montserrat, F; Meysman, F.J.R.

    2014-01-01

    Porewater profiles and sediment-water fluxes of oxygen, nutrients, pH, calcium, alkalinity, and sulfide were measured in intertidal sandflat sediments from the Oosterschelde mesotidal lagoon (The Netherlands). The influence of bioturbation and bioirrigation by the deep-burrowing polychaete

  19. Alkalinity production in intertidal sands intensified by lugworm bioirrigation.

    Science.gov (United States)

    Rao, Alexandra M F; Malkin, Sairah Y; Montserrat, Francesc; Meysman, Filip J R

    2014-07-05

    Porewater profiles and sediment-water fluxes of oxygen, nutrients, pH, calcium, alkalinity, and sulfide were measured in intertidal sandflat sediments from the Oosterschelde mesotidal lagoon (The Netherlands). The influence of bioturbation and bioirrigation by the deep-burrowing polychaete Arenicola marina on the rates and sources of benthic alkalinity generation was examined by comparing measurements in intact and defaunated sediment cores before and after the addition of A. marina in summer and fall 2011. Higher organic matter remineralization rates, shallower O 2 penetration, and greater sediment-water solute fluxes were observed in summer, consistent with higher sediment community metabolic rates at a higher temperature. Lugworm activity stimulated porewater exchange (5.1 × in summer, 1.9 × in fall), organic matter remineralization (6.2 × in summer, 1.9 × in fall), aerobic respiration (2.4 × in summer, 2.1 × in fall), alkalinity release (4.7 × in summer, 4.0 × in fall), nutrient regeneration, and iron cycling. The effects of lugworm activity on net sediment-water fluxes were similar but more pronounced in summer than in fall. Alkalinity release in fall was entirely driven by metabolic carbonate dissolution, while this process explained between 22 and 69% of total alkalinity production in summer, indicating the importance of other processes in this season. By enhancing organic matter remineralization and the reoxidation of reduced metabolites by the sediment microbial community, lugworm activity stimulated the production of dissolved inorganic carbon and metabolic acidity, which in turn enhanced metabolic CaCO 3 dissolution efficiency. In summer, evidence of microbial long distance electron transport (LDET) was observed in defaunated sediment. Thus, alkalinity production by net carbonate dissolution was likely supplemented by anaerobic respiration and LDET in summer.

  20. Intensified multifactorial treatment of patients with Type 2 diabetes

    DEFF Research Database (Denmark)

    Pedersen, Oluf

    2009-01-01

    By influencing the standards of diabetes care and treatment guidelines throughout the world, the results of recent long-term risk factor interventions in Type 2 diabetes (T2D) have likely contributed to the improved health outcomes and induced a decline in mortality in people with T2D. Although we...... have a need for even more evidence to support early, individualized, and intensive management of all known modifiable risk factors, we have now reached an era in T2D care where the critical challenges appear to be to translate the insights, knowledge and benefits to patients in the community setting....... Current surveys show slow progress in achieving treatment goals and in the use of recommended drugs and adjustments of lifestyle for the prevention of vascular complications in diabetes. The resistance and barriers among medical professionals and patients likely have multiple causes. The present review...

  1. Hope for the future: intensifying spirituality in the workplace.

    Science.gov (United States)

    Batcheller, Joyce; Davis, James; Yoder-Wise, Patricia S

    2013-01-01

    Healthy workplaces address various issues. Work focused on ergonomics addresses physical issues, satisfaction surveys reveal psychosocial issues; and other approaches address spirituality issues. Spirituality in the workplace contributes to holistic care and to the worth of the individual. Incorporating the concept of spirituality, in its broad sense, into the workplace enriches leadership practice and contributes to a holistic work environment. Spirituality is core to the servant leader approach to leadership and beneficial to other approaches. Followers benefit from a holistic approach to leadership; and some specific practices can exhibit the belief an organization holds related to the worth of the individual. Incorporating spirituality into an organization reflects the same values nursing holds for person-centered care, a view of integration of physical, psychological, and spiritual needs.

  2. Intensified tuberculosis case finding among hiv-infected individuals

    African Journals Online (AJOL)

    2011-10-02

    burden ... active TB (and in need of treatment) or being free of TB disease (and warranting ... following symptoms – current cough, fever, weight loss or night sweats (CFWS) .... and stand-alone HIV testing services. The WHO ...

  3. Spatial and temporal variation of repetitive plasma discharges in saline solutions

    International Nuclear Information System (INIS)

    Stalder, K R; Nersisyan, G; Graham, W G

    2006-01-01

    Repetitive plasma discharges developed in saline solutions have been investigated using fast, intensified charge coupled detector imaging techniques. The images show that synchronously pulsed multielectrode configurations tend to develop intense, transient plasma regions somewhat randomly in both space and time on short (10 μs) time scales, even though they appear to be stationary on longer (tens of milliseconds) time scales. Evidence for the production of both strongly ionized and weakly ionized plasmas is also presented

  4. Usefulness of DICOM headers in the analysis of two biplane X-ray systems setting (image intensifier and flat panel) used in pediatric interventional cardiology in Chile;Utilidad de las cabeceras DICOM en el analisis de la configuracion de dos sistemas de rayos X biplano (intensificador de imagen y panel plano) utilizados en cardiologia intervencionista pediatrica en Chile

    Energy Technology Data Exchange (ETDEWEB)

    Ubeda, C.; Vergara, F. [Universidad de Tarapaca, Arica (Chile). Dept. de Ciencias Clinicas; Vano, E. [Universidad Complutense, Madrid, (Spain). Hospital Clinico San Carlos. Dept. de Radiologia; Miranda, P. [Hospital Luis Calvo Mackenna, Santiago (Chile). Dept. de Hemodinamia; Valenzuela, E. [Universidad Catolica de Chile, Santiago (Chile). Hospital Clinico. Servicio de Hemodinamia; Leyton, F. [Instituto de Salud Publica de Chile, Santiago (Chile)

    2009-07-01

    The setting of two biplane X ray systems were evaluated (image intensifier (II) and flat panel (PP)), through DICOM tags from 32 images created during the characterization of both systems. The technical parameters adjusted for systems were: 63,8 to 80,0 kV and 15,0 to 388,0 mA, for the system with II and 52,0 to 77,0 kV and 25,0 to 476,0 mA, for the system with PP detector. Both equipment presented a different mA adjustment, when moving from fluoroscopy modes low dose (FL), medium dose (FM) and high dose (FH) to cine mode (CI). Two dosimetric quantities were evaluated, the first one was the dose-area product (DAP) which gave as a result for FB mode, between 0,03 to 0,35 uGycm{sup 2}/image (II) and from 0,05 a 0,69 uGycm{sup 2}/image (PP), when the polymethyl methacrylate (PMMA) thickness was incremented from 4 to 16 cm. In cine mode the DAP quantity showed, percentage values from 24 to -1 % for the same PMMA increment. Skin cumulative dose was the second quantity evaluated and showed an increment of incident air kerma (KAI)/image in factors from 17 to 35 (II) and 15 to 28 (PP) when used in CI mode instead of FB mode, to the different PMMA thicknesses used. This dose increment for CI mode must be considered by cardiologists, to use the fluoroscopic run as an alternative to document part of the procedures when there is no need to use a high quality image (author)

  5. A exposição à fumaça de cigarro intensifica a remodelação ventricular após o infarto agudo do miocárdio Cigarette smoke exposure intensifies ventricular remodeling process following myocardial infarction

    Directory of Open Access Journals (Sweden)

    Leonardo A. M. Zornoff

    2006-04-01

    . RESULTS: The CSE animals tended to have larger diastolic (C = 1.5 ± 0.4 mm², F = 1.9 ± 0.4 mm²; p = 0.08 and systolic (C = 1.05 ± 0.3 mm², F = 1.32 ± 0.4 mm²; p = 0.08 left ventricular(LV areas. The systolic function of the LV, assessed according to the fractional area change, tended to be impaired in CSE animals (C = 31.9 ± 9.3%, F = 25.5 ± 7.6%; p = 0.08. The - dp/dt values for CSE animals were statistically lower (C = 1474 ± 397 mmHg, F = 916 ± 261 mmHg; p = 0.02 than for control animals. The CSE animals presented higher right ventricle (RV weight adjusted for body weight (C = 0.8 ± 0.3 mg/g, F = 1.3 ± 0.4 mg/g; p = 0.01, higher content of water in lungs (C = 4.8 (4.3-4.8%, F = 5.4 (5.1-5.5; p = 0.03, and larger LV myocyte cross-sectional areas (C = 239.8 ± 5.8 µm², F = 253.9 ± 7.9 µm²; p = 0.01. CONCLUSION: Cigarette smoke exposure intensifies ventricular remodeling following acute myocardial infarction.

  6. Particle influx measurements with the ASDEX-upgrade multichord visible spectroscopy system

    International Nuclear Information System (INIS)

    Kallenbach, A.; Mayer, H.M.; Schneider, W.

    1992-01-01

    This report describes the hardware and software components of the ASDEX-Upgrade multichord visible spectroscopy system. Main emphasis is laid on a detailed description of the detector, a free programmable charge-coupled device intensified by a microchannel plate. As an experimental application, flux measurements of different impurity species from the inner heat shield are presented. Poloidal profiles of the released impurity amount obtained for various experimental situations are used to check the plasma position which is derived by the function parametrization analysis. (orig.)

  7. A Thomson-type mass and energy spectrometer for characterizing ion energy distributions in a coaxial plasma gun operating in a gas-puff mode

    OpenAIRE

    Rieker, G. B.; Poehlmann, F. R.; Cappelli, M. A.

    2013-01-01

    Measurements of ion energy distribution are performed in the accelerated plasma of a coaxial electromagnetic plasma gun operating in a gas-puff mode at relatively low discharge energy (900 J) and discharge potential (4 kV). The measurements are made using a Thomson-type mass and energy spectrometer with a gated microchannel plate and phosphor screen as the ion sensor. The parabolic ion trajectories are captured from the sensor screen with an intensified charge-coupled detector camera. The spe...

  8. Role of secondary emission on discharge dynamics in an atmospheric pressure dielectric barrier discharge

    Energy Technology Data Exchange (ETDEWEB)

    Tay, W. H.; Kausik, S. S.; Yap, S. L.; Wong, C. S., E-mail: cswong@um.edu.my [Plasma Technology Research Centre, Department of Physics, Faculty of Science, University of Malaya, 50603 Kuala Lumpur (Malaysia)

    2014-04-15

    The discharge dynamics in an atmospheric pressure dielectric barrier discharge (DBD) is studied in a DBD reactor consisting of a pair of stainless steel parallel plate electrodes. The DBD discharge has been generated by a 50 Hz ac high voltage power source. The high-speed intensified charge coupled device camera is used to capture the images of filaments occurring in the discharge gap. It is observed that frequent synchronous breakdown of micro discharges occurs across the discharge gap in the case of negative current pulse. The experimental results reveal that secondary emissions from the dielectric surface play a key role in the synchronous breakdown of plasma filaments.

  9. Spectroscopic analysis of Zirconium plasma in different ambient and optimizing conditions for nanoclusters formation

    International Nuclear Information System (INIS)

    Yadav, Dheerendra; Thareja, Raj K.

    2010-01-01

    The laser produced zirconium plasma has been studied by emission spectroscopy and fast photography using intensified charged coupled device at different ambient pressures of nitrogen (0.1, 1.0 and 10 mbar). Formation of zirconium clusters are arising at ambient pressure of 1.0 mbar at the plume periphery due to the chemical reactions between the plasma plume and the ambient and confirmed using optical emission spectroscopy. The optimum parameters for existence cluster formation are reported. The ZrN clusters are deposited on silicon substrate and characterized by AFM, XRD and EDAX techniques. (author)

  10. Columnar discharge mode between parallel dielectric barrier electrodes in atmospheric pressure helium

    Energy Technology Data Exchange (ETDEWEB)

    Hao, Yanpeng; Zheng, Bin; Liu, Yaoge [School of Electric Power, South China University of Technology, Guangzhou 510640 (China)

    2014-01-15

    Using a fast-gated intensified charge-coupled device, end- and side-view photographs were taken of columnar discharge between parallel dielectric barrier electrodes in atmospheric pressure helium. Based on three-dimensional images generated from end-view photographs, the number of discharge columns increased, whereas the diameter of each column decreased as the applied voltage was increased. Side-view photographs indicate that columnar discharges exhibited a mode transition ranging from Townsend to glow discharges generated by the same discharge physics as atmospheric pressure glow discharge.

  11. Camera selection for real-time in vivo radiation treatment verification systems using Cherenkov imaging.

    Science.gov (United States)

    Andreozzi, Jacqueline M; Zhang, Rongxiao; Glaser, Adam K; Jarvis, Lesley A; Pogue, Brian W; Gladstone, David J

    2015-02-01

    To identify achievable camera performance and hardware needs in a clinical Cherenkov imaging system for real-time, in vivo monitoring of the surface beam profile on patients, as novel visual information, documentation, and possible treatment verification for clinicians. Complementary metal-oxide-semiconductor (CMOS), charge-coupled device (CCD), intensified charge-coupled device (ICCD), and electron multiplying-intensified charge coupled device (EM-ICCD) cameras were investigated to determine Cherenkov imaging performance in a clinical radiotherapy setting, with one emphasis on the maximum supportable frame rate. Where possible, the image intensifier was synchronized using a pulse signal from the Linac in order to image with room lighting conditions comparable to patient treatment scenarios. A solid water phantom irradiated with a 6 MV photon beam was imaged by the cameras to evaluate the maximum frame rate for adequate Cherenkov detection. Adequate detection was defined as an average electron count in the background-subtracted Cherenkov image region of interest in excess of 0.5% (327 counts) of the 16-bit maximum electron count value. Additionally, an ICCD and an EM-ICCD were each used clinically to image two patients undergoing whole-breast radiotherapy to compare clinical advantages and limitations of each system. Intensifier-coupled cameras were required for imaging Cherenkov emission on the phantom surface with ambient room lighting; standalone CMOS and CCD cameras were not viable. The EM-ICCD was able to collect images from a single Linac pulse delivering less than 0.05 cGy of dose at 30 frames/s (fps) and pixel resolution of 512 × 512, compared to an ICCD which was limited to 4.7 fps at 1024 × 1024 resolution. An intensifier with higher quantum efficiency at the entrance photocathode in the red wavelengths [30% quantum efficiency (QE) vs previous 19%] promises at least 8.6 fps at a resolution of 1024 × 1024 and lower monetary cost than the EM-ICCD. The

  12. Double-gated spectral snapshots for biomolecular fluorescence

    International Nuclear Information System (INIS)

    Nakamura, Ryosuke; Hamada, Norio; Ichida, Hideki; Tokunaga, Fumio; Kanematsu, Yasuo

    2007-01-01

    A versatile method to take femtosecond spectral snapshots of fluorescence has been developed based on a double gating technique in the combination of an optical Kerr gate and an image intensifier as an electrically driven gate set in front of a charge-coupled device detector. The application of a conventional optical-Kerr-gate method is limited to molecules with the short fluorescence lifetime up to a few hundred picoseconds, because long-lifetime fluorescence itself behaves as a source of the background signal due to insufficiency of the extinction ratio of polarizers employed for the Kerr gate. By using the image intensifier with the gate time of 200 ps, we have successfully suppressed the background signal and overcome the application limit of optical-Kerr-gate method. The system performance has been demonstrated by measuring time-resolved fluorescence spectra for laser dye solution and the riboflavin solution as a typical sample of biomolecule

  13. Development of a high-resolution Thomson scattering system for plasma interactions with molten salt (FLiNaK)

    Energy Technology Data Exchange (ETDEWEB)

    Lee, K. Y. [National Fusion Research Institute, Gunsan (Korea, Republic of)

    2014-10-15

    A high-resolution Thomson scattering system is presently being developed to measure the electron temperature and density profile during plasma interaction with molten salt. The system uses a 20-Hz Nd:YAG laser operating at the second harmonic (532 nm). The collection lens, having a 1:10 magnification ratio, measures 63 points along the 10-cm profile. The scattered light is transmitted by using an optical-fiber bundle, and is analyzed with a triple-grating spectrometer to further reduce stray light. Its spectral resolution is expected to be 0.03 nm. An intensified charge-coupled device (ICCD) camera consisting of a gated image intensifier coupled to the CCD camera is used to record the spectral distribution of the scattered light. An additional feature of operating the ICCD camera at 40-Hz to record the background signal is incorporated.

  14. Distortion correction for x-ray image intensifiers: Local unwarping polynomials and RBF neural networks

    International Nuclear Information System (INIS)

    Cerveri, P.; Forlani, C.; Borghese, N.A.; Ferrigno, G.

    2002-01-01

    In this paper we present two novel techniques, namely a local unwarping polynomial (LUP) and a hierarchical radial basis function (HRBF) network, to correct geometric distortions in XRII images. The two techniques have been implemented and compared, in terms of residual error measured at control and intermediate points, with local and global methods reported in the previous literature. In particular, LUP rests on a locally optimized 3rd degree polynomial applied within each quadrilateral cell on the rectilinear calibration grid of points. HRBF, based on a feed-forward neural network paradigm, is constituted by a set of hierarchical layers at increasing cut-off frequency, each characterized by a set of Gaussian functions. Extensive experiments have been performed both on simulated and real data. In simulation, we tested the effect of pincushion, sigmoidal and local distortions, along with the number of calibration points. Provided that a sufficient number of cells of the calibration grid is available, the obtained accuracy for both LUP and HRBF is comparable to or better than that of global polynomial technique. Tests on real data, carried out by using two different (12 in. and 16 in.) XRIIs, showed that the global polynomial accuracy (0.16±0.08 pixels) is slightly worse than that of LUP (0.07±0.05 pixels) and HRBF (0.08±0.04 pixels). The effects of the discontinuity at the border of the local areas and the decreased accuracy at intermediate points, typical of local techniques, have been proved to be smoothed for both LUP and HRBF

  15. Fluid intensifier having a double acting power chamber with interconnected signal rods

    Science.gov (United States)

    Whitehead, John C.

    2001-01-01

    A fluid driven reciprocating apparatus having a double acting power chamber with signal rods serving as high pressure pistons, or to transmit mechanical power. The signal rods are connected to a double acting piston in the power chamber thereby eliminating the need for pilot valves, with the piston being controlled by a pair of intake-exhaust valves. The signal rod includes two spaced seals along its length with a vented space therebetween so that the driving fluid and driven fluid can't mix, and performs a switching function to eliminate separate pilot valves. The intake-exhaust valves can be integrated into a single housing with the power chamber, or these valves can be built into the cylinder head only of the power chamber, or they can be separate from the power chamber.

  16. Compound extremes of summer temperature and precipitation leading to intensified departures from natural variability.

    Science.gov (United States)

    Mahony, C. R.; Cannon, A. J.

    2017-12-01

    Climate change can drive local climates outside the range of their historical year-to-year variability, straining the adaptive capacity of ecological and human communities. We demonstrate that interactions between climate variables can produce larger and earlier departures from natural variability than is detectable in individual variables. For example, summer temperature (Tx) and precipitation (Pr) are negatively correlated in most terrestrial regions, such that interannual variability lies along an axis from warm-and-dry to cool-and-wet conditions. A climate change trend perpendicular to this axis, towards warmer-wetter conditions, can depart more quickly from the range of natural variability than a warmer-drier trend. This multivariate "departure intensification" effect is evident in all six CMIP5 models that we examined: 23% (9-34%) of the land area of each model exhibits a pronounced increase in 2σ extremesin the Tx-Pr regime relative to Tx or Pr alone. Observational data suggest that Tx-Pr correlations are sufficient to produce departure intensification in distinct regions on all continents. Departures from the historical Tx-Pr regime may produce ecological disruptions, such as in plant-pathogen interactions and human diseases, that could offset the drought mitigation benefits of increased precipitation. Our study alerts researchers and adaptation practitioners to the presence of multivariate climate change signals and compound extremes that are not detectable in individual climate variables.

  17. Acupuncture Induces a Pro-Inflammatory Immune Response Intensified by a Conditioning-Expectation Effect

    DEFF Research Database (Denmark)

    Karst, M; Schneidewind, D; Schneinichen, D

    2010-01-01

    BACKGROUND: In a previous study it has been shown that acupuncture activates the respiratory burst (RB) of neutrophils as measured by the differences to baseline of the mean channel number of fluorescence intensity (mfi) in volunteers. Since this result could have been affected by a placebo effect......, a study has been designed that controls for the different facets of placebo mechanisms such as expectancy, suggestibility, and conditioning. PARTICIPANTS AND METHODS: 60 healthy volunteers were randomized either to acupuncture of the acupoint Large Intestine 11 (LI 11) (groups 1 and 2) or relaxation...... (group 3) twice a week for 4 weeks. Only acupuncture group 1 and the relaxation group were provided with the additional suggestion that the treatment may strengthen the immune system. RESULTS: The repeated measurement analysis for differences of follow-ups to baseline showed significantly different...

  18. Acupuncture induces a pro-inflammatory immune response intensified by a conditioning-expectation effect

    DEFF Research Database (Denmark)

    Karst, M.; Schneidewind, D.; Scheinchen, D.

    2010-01-01

    BACKGROUND: In a previous study it has been shown that acupuncture activates the respiratory burst (RB) of neutrophils as measured by the differences to baseline of the mean channel number of fluorescence intensity (mfi) in volunteers. Since this result could have been affected by a placebo effect......, a study has been designed that controls for the different facets of placebo mechanisms such as expectancy, suggestibility, and conditioning. PARTICIPANTS AND METHODS: 60 healthy volunteers were randomized either to acupuncture of the acupoint Large Intestine 11 (LI 11) (groups 1 and 2) or relaxation...... (group 3) twice a week for 4 weeks. Only acupuncture group 1 and the relaxation group were provided with the additional suggestion that the treatment may strengthen the immune system. RESULTS: The repeated measurement analysis for differences of follow-ups to baseline showed significantly different...

  19. Intensifying the Dominant Response II: Nonconscious Negative Affect, Cognitive Demand, and Conversations.

    Science.gov (United States)

    Monahan, Jennifer L.; Laliker, Melanie

    2002-01-01

    Examines mechanisms that may account for why evaluations made by participants involved in conversations are more influenced by subliminal negative cues than are evaluations made by observers. Explains three studies in which subliminal priming tasks were used with differing cognitive loads and self-preservation concerns among a group of…

  20. Systemic and intensifying drought induces collapse and replacement of native fishes: a time-series approach

    Science.gov (United States)

    Ruhi, A.; Olden, J. D.; Sabo, J. L.

    2015-12-01

    In the American Southwest, hydrologic drought has become a new normal as a result of increasing human appropriation of freshwater resources and increased aridity associated with global warming. Although drought has often been touted to threaten freshwater biodiversity, connecting drought to extinction risk of highly-imperiled faunas remains a challenge. Here we combine time-series methods from signal processing and econometrics to analyze a spatially comprehensive and long-term dataset to link discharge variation and community abundance of fish across the American Southwest. This novel time series framework identifies ongoing trends in daily discharge anomalies across the Southwest, quantifies the effect of the historical hydrologic drivers on fish community abundance, and allows us to simulate species trajectories and range-wide risk of decline (quasiextinction) under scenarios of future climate. Spectral anomalies are declining over the last 30 years in at least a quarter of the stream gaging stations across the American Southwest and these anomalies are robust predictors of historical abundance of native and non-native fishes. Quasiextinction probabilities are high (>50 %) for nearly ¾ of the native species across several large river basins in the same region; and the negative trend in annual anomalies increases quasiextinction risk for native but reduces this risk for non-native fishes. These findings suggest that ongoing drought is causing range-wide collapse and replacement of native fish faunas, and that this homogenization of western fish faunas will continue given the prevailing negative trend in discharge anomalies. Additionally, this combination of methods can be applied elsewhere as long as environmental and biological long-term time-series data are available. Collectively, these methods allow identifying the link between hydroclimatic forcing and ecological responses and thus may help anticipating the potential impacts of ongoing and future hydrologic extremes in freshwater ecosystems.

  1. Nutritional practices of elite swimmers during an intensified training camp: with particular reference to antioxidants.

    Science.gov (United States)

    Slattery, K M; Coutts, A J; Wallace, L K

    2012-10-01

    Athletes should match their energy intake with expenditure in order to maintain lean body mass. It is also important to consume adequate amounts of antioxidant vitamins and minerals to maintain health. To assess the dietary habits of six nationally ranked Australian swimmers physical training load and dietary intake (24 h food recall) and were recorded on a daily basis during a 4 day intensive physical training period. The results showed no significant difference between energy intake and expenditure (P=0.58) or the amount of carbohydrate consumed (P=0.14) compared to the Australian recommended daily intake (RDI). Athletes reported a significantly greater intake of vitamin A (P<0.01), vitamin C (P<0.01), vitamin E (P<0.01) and protein (P<0.01) than the RDI. It was concluded that these elite swimmers have an adequate dietary intake to allow for optimal physical training and performance.

  2. Thermokarst rates intensify due to climate change and forest fragmentation in an Alaskan boreal forest lowland

    Science.gov (United States)

    Lara, M.; Genet, Helene; McGuire, A. David; Euskirchen, Eugénie S.; Zhang, Yujin; Brown, Dana R. N.; Jorgenson, M.T.; Romanovsky, V.; Breen, Amy L.; Bolton, W.R.

    2016-01-01

    Lowland boreal forest ecosystems in Alaska are dominated by wetlands comprised of a complex mosaic of fens, collapse-scar bogs, low shrub/scrub, and forests growing on elevated ice-rich permafrost soils. Thermokarst has affected the lowlands of the Tanana Flats in central Alaska for centuries, as thawing permafrost collapses forests that transition to wetlands. Located within the discontinuous permafrost zone, this region has significantly warmed over the past half-century, and much of these carbon-rich permafrost soils are now within ~0.5 °C of thawing. Increased permafrost thaw in lowland boreal forests in response to warming may have consequences for the climate system. This study evaluates the trajectories and potential drivers of 60 years of forest change in a landscape subjected to permafrost thaw in unburned dominant forest types (paper birch and black spruce) associated with location on elevated permafrost plateau and across multiple time periods (1949, 1978, 1986, 1998, and 2009) using historical and contemporary aerial and satellite images for change detection. We developed (i) a deterministic statistical model to evaluate the potential climatic controls on forest change using gradient boosting and regression tree analysis, and (ii) a 30 × 30 m land cover map of the Tanana Flats to estimate the potential landscape-level losses of forest area due to thermokarst from 1949 to 2009. Over the 60-year period, we observed a nonlinear loss of birch forests and a relatively continuous gain of spruce forest associated with thermokarst and forest succession, while gradient boosting/regression tree models identify precipitation and forest fragmentation as the primary factors controlling birch and spruce forest change, respectively. Between 1950 and 2009, landscape-level analysis estimates a transition of ~15 km² or ~7% of birch forests to wetlands, where the greatest change followed warm periods. This work highlights that the vulnerability and resilience of lowland ice-rich permafrost ecosystems to climate changes depend on forest type.

  3. Intensifying Insecurities: The impact of climate change on vulnerability to human trafficking in the Indian Sundarbans

    Directory of Open Access Journals (Sweden)

    Nicole Molinari

    2017-04-01

    Full Text Available Despite an enormous amount of attention paid to the factors that shape vulnerability to human trafficking, such as poverty and a lack of economic opportunity, the debate of evidence for what enables these factors to exist in the first place is relatively less explored. Presently, discussions of the relationship between climate change and human insecurity have been marginal to broader debates about vulnerability to trafficking. This paper argues that this signifies a gap in our understanding of the underlying drivers that push individuals and communities into situations where vulnerability to trafficking amplifies, but also that increase the pull of risky migration pathways and exploitative work situations. This paper proceeds by examining and problematising dominant conceptualisations of vulnerability in human trafficking and climate change discourses. Next, it presents a case study of the Sundarbans region of India to highlight how climate change impacts compound and exacerbate the same factors that shape vulnerability to human trafficking—including environmental degradation, loss of livelihood, destitution, and forced migration. Lastly, it argues for enhanced attention to climate change-related insecurity as evidence of vulnerability to trafficking and outlines what such insights can bring to anti-trafficking efforts.

  4. Strategic Engagement of Technical Surge Capacity for Intensified Polio Eradication Initiative in Nigeria, 2012–2015

    Science.gov (United States)

    Yehualashet, Yared G.; Mkanda, Pascal; Gasasira, Alex; Erbeto, Tesfaye; Onimisi, Anthony; Horton, Janet; Banda, Richard; Tegegn, Sisay G.; Ahmed, Haruna; Afolabi, Oluwole; Wadda, Alieu; Vaz, Rui G.; Nsubuga, Peter

    2016-01-01

    Background. Following the 65th World Health Assembly (WHA) resolution on intensification of the Global Poliomyelitis Eradication Initiative (GPEI), the Nigerian government, with support from the World Health Organization (WHO) and other partners, implemented a number of innovative strategies to curb the transmission of wild poliovirus (WPV) in the country. One of the innovations successfully implemented since mid 2012 is the WHO's engagement of surge capacity personnel. Methods. The WHO reorganized its functional structure, adopted a transparent recruitment and deployment process, provided focused technical and management training, and applied systematic accountability framework to successfully manage the surge capacity project in close collaboration with the national counterparts and partners. The deployment of the surge capacity personnel was guided by operational and technical requirement analysis. Results. Over 2200 personnel were engaged, of whom 92% were strategically deployed in 11 states classified as high risk on the basis of epidemiological risk analysis and compromised security. These additional personnel were directly engaged in efforts aimed at improving the performance of polio surveillance, vaccination campaigns, increased routine immunization outreach sessions, and strengthening partnership with key stakeholders at the operational level, including community-based organizations. Discussion. Programmatic interventions were sustained in states in which security was compromised and the risk of polio was high, partly owing to the presence of the surge capacity personnel, who are engaged from the local community. Since mid-2012, significant programmatic progress was registered in the areas of polio supplementary immunization activities, acute flaccid paralysis surveillance, and routine immunization with the support of the surge capacity personnel. As of 19 June 2015, the last case of WPV was reported on 24 July 2014. The surge infrastructure has also been instrumental in building local capacity; supporting other public health emergencies, such as the Ebola outbreak response and measles and meningitis outbreaks; and strengthening the integrated disease surveillance and response. Due to weak health systems in the country, it is vital to maintain a reasonable level of the surge capacity for successful implementation of the 2013–2018 global polio endgame strategy and beyond. PMID:26912379

  5. Mechanisms of basin-scale nitrogen load reductions under intensified irrigated agriculture.

    Directory of Open Access Journals (Sweden)

    Rebecka Törnqvist

    Full Text Available Irrigated agriculture can modify the cycling and transport of nitrogen (N, due to associated water diversions, water losses, and changes in transport flow-paths. We investigate dominant processes behind observed long-term changes in dissolved inorganic nitrogen (DIN concentrations and loads of the extensive (465,000 km2 semi-arid Amu Darya River basin (ADRB in Central Asia. We specifically considered a 40-year period (1960-2000 of large irrigation expansion, reduced river water flows, increased fertilizer application and net increase of N input into the soil-water system. Results showed that observed decreases in riverine DIN concentration near the Aral Sea outlet of ADRB primarily were due to increased recirculation of irrigation water, which extends the flow-path lengths and enhances N attenuation. The observed DIN concentrations matched a developed analytical relation between concentration attenuation and recirculation ratio, showing that a fourfold increase in basin-scale recirculation can increase DIN attenuation from 85 to 99%. Such effects have previously only been observed at small scales, in laboratory experiments and at individual agricultural plots. These results imply that increased recirculation can have contributed to observed increases in N attenuation in agriculturally dominated drainage basins in different parts of the world. Additionally, it can be important for basin scale attenuation of other pollutants, including phosphorous, metals and organic matter. A six-fold lower DIN export from ADRB during the period 1981-2000, compared to the period 1960-1980, was due to the combined result of drastic river flow reduction of almost 70%, and decreased DIN concentrations at the basin outlet. Several arid and semi-arid regions around the world are projected to undergo similar reductions in discharge as the ADRB due to climate change and agricultural intensification, and may therefore undergo comparable shifts in DIN export as shown here for the ADRB. For example, projected future increases of irrigation water withdrawals between 2005 and 2050 may decrease the DIN export from arid world regions by 40%.

  6. Soil and water conservation in the Pacific Northwest through no-tillage and intensified crop rotations

    Science.gov (United States)

    The winter wheat (Triticum aestivum L.) summer fallow rotation typically practiced in the intermediate precipitation zone [300-450 mm (12-18 in)] of the inland Pacific Northwest has proven to be economically stable for producers in this region. However multiple tillage operations are used to control...

  7. Design and implementation of an intensified coprecipitation reactor for the treatment of liquid radioactive wastes

    International Nuclear Information System (INIS)

    Flouret, Julie; Barre, Yves; Muhr, Herve; Plasari, Edouard

    2013-01-01

    The coprecipitation is a robust and inexpensive process for the treatment of important volumes of low and intermediate radioactive level liquid wastes. Its major inconvenient is the huge volume of sludge generated. The purpose of this work is to optimize the industrial coprecipitation continuous process by achieving the following objectives: - maximize the decontamination efficiency; - minimize the volume of sludge generated by the process; - reduce the treatment cost decreasing the installation volume. An innovative reactor with an infinite recycling ratio was therefore designed. It is a multifunctional reactor composed of two zones: a perfectly mixed precipitation zone and a classifier to perform liquid-solid separation. The experiments are focused on the coprecipitation of strontium by barium sulphate. The effluent containing sulphate ions and the barium nitrate solution are injected in the reaction zone where strontium and barium co-precipitate as sulphates. The produced solid phase is returned into the reaction zone by the classifier and goes out slowly from the reactor bottom with a residence time much higher than the liquid phase. This creates both a high concentration of solid phase in the reaction zone and a high efficiency of decontamination. The experimental conditions simulate the industrial effluents. The total treatment flow rate is 17 L/h, with an effluent flow rate of 16 L/h and a reactive flow rate of 1 L/h, hence a mean residence time of 10 minutes. In these experimental conditions, the molar ratio sulphate/barium after mixing corresponds to 4.9. These conditions are used in the reprocessing plant of La Hague. The decontamination factor reached in these experimental conditions is excellent: DF = 1500. The decontamination factor obtained with the classical continuous process is only equal to 60. Different process parameters are studied in order to optimize the reactor/classifier: residence time, barium nitrate flow rate and racking flow rate. The decrease of barium nitrate flow rate reduces the volume of sludge generated by the process keeping a high efficiency of strontium decontamination: DF = 400. An excess of sulphate is necessary to perform an efficient decontamination, but the molar ratio sulphate/barium can be reduced to 3 instead of 4.9 used industrially. The reactor/classifier also represents an efficient device for the coprecipitation process intensification. Indeed, it can sensibly reduce the final installation size while treating important volume of effluents. This innovative reactor optimizes both the decontamination efficiency of radioactive liquid wastes and the reduction of sludge volume. A reduction of sulphate ions in the discharge is also possible, which is environmentally friendly. (authors)

  8. Strategic Engagement of Technical Surge Capacity for Intensified Polio Eradication Initiative in Nigeria, 2012-2015.

    Science.gov (United States)

    Yehualashet, Yared G; Mkanda, Pascal; Gasasira, Alex; Erbeto, Tesfaye; Onimisi, Anthony; Horton, Janet; Banda, Richard; Tegegn, Sisay G; Ahmed, Haruna; Afolabi, Oluwole; Wadda, Alieu; Vaz, Rui G; Nsubuga, Peter

    2016-05-01

    Following the 65th World Health Assembly (WHA) resolution on intensification of the Global Poliomyelitis Eradication Initiative (GPEI), the Nigerian government, with support from the World Health Organization (WHO) and other partners, implemented a number of innovative strategies to curb the transmission of wild poliovirus (WPV) in the country. One of the innovations successfully implemented since mid 2012 is the WHO's engagement of surge capacity personnel. The WHO reorganized its functional structure, adopted a transparent recruitment and deployment process, provided focused technical and management training, and applied systematic accountability framework to successfully manage the surge capacity project in close collaboration with the national counterparts and partners. The deployment of the surge capacity personnel was guided by operational and technical requirement analysis. Over 2200 personnel were engaged, of whom 92% were strategically deployed in 11 states classified as high risk on the basis of epidemiological risk analysis and compromised security. These additional personnel were directly engaged in efforts aimed at improving the performance of polio surveillance, vaccination campaigns, increased routine immunization outreach sessions, and strengthening partnership with key stakeholders at the operational level, including community-based organizations. Programmatic interventions were sustained in states in which security was compromised and the risk of polio was high, partly owing to the presence of the surge capacity personnel, who are engaged from the local community. Since mid-2012, significant programmatic progress was registered in the areas of polio supplementary immunization activities, acute flaccid paralysis surveillance, and routine immunization with the support of the surge capacity personnel. As of 19 June 2015, the last case of WPV was reported on 24 July 2014. The surge infrastructure has also been instrumental in building local capacity; supporting other public health emergencies, such as the Ebola outbreak response and measles and meningitis outbreaks; and strengthening the integrated disease surveillance and response. Due to weak health systems in the country, it is vital to maintain a reasonable level of the surge capacity for successful implementation of the 2013-2018 global polio endgame strategy and beyond. © 2016 World Health Organization; licensee Oxford Journals.

  9. Intensified multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria

    DEFF Research Database (Denmark)

    Gaede, P; Vedel, P; Parving, H H

    1999-01-01

    allocated standard treatment (n=80) or intensive treatment (n=80). Standard treatment followed Danish guidelines. Intensive treatment was a stepwise implementation of behaviour modification, pharmacological therapy targeting hyperglycaemia, hypertension, dyslipidaemia, and microalbuminuria. The primary...... endpoint was the development of nephropathy (median albumin excretion rate >300 mg per 24 h in at least one of the two-yearly examinations). Secondary endpoints were the incidence or progression of diabetic retinopathy and neuropathy. FINDINGS: The mean age was 55.1 years (SD 7.2) and patients were...

  10. Will the western Pacific subtropical high constantly intensify in the future?

    Science.gov (United States)

    Huang, Yanyan; Li, Xiaofan; Wang, Huijun

    2016-07-01

    The western Pacific subtropical high (WPSH) features lower-level southerlies or southwesterlies at its western and southern edges that transport amount of water vapor into East Asia, and it exerts a large influence on the East Asian summer climate. This paper evaluates the historical (1950-2005) spatial distribution and variability in the summer WPSH at 850 hPa using 28 general circulation models from the Coupled Model Intercomparison Project Phase 5 (CMIP5) relative to the NCEP-NCAR reanalysis data. To avoid the artificial influence caused by global warming, this study primarily investigates the 850-hPa eddy geopotential height and the horizontal winds. The results show that most of the CMIP5 models reliably reproduce the geographical distribution and spatial variability in the WPSH. Four models (bcc-csm1-1, CESM1-CAM5, GFDL-ESM2G and inmcm4) generally perform well in simulating the eastward-recessed interdecadal variation in the WPSH during 1979-2005 relative to 1950-1978, with a significant cyclone anomaly appearing over the western Pacific and a decreasing trend in the WPSH index. Based on these four models, a multi-model ensemble projects a weaker WPSH during 2026-2070 relative to 2010-2025 and 2071-2100 under the representative concentration pathway 8.5 scenario.

  11. Intensified Arctic warming under greenhouse warming by vegetation–atmosphere–sea ice interaction

    International Nuclear Information System (INIS)

    Jeong, Jee-Hoon; Kug, Jong-Seong; Linderholm, Hans W; Chen, Deliang; Kim, Baek-Min; Jun, Sang-Yoon

    2014-01-01

    Observations and modeling studies indicate that enhanced vegetation activities over high latitudes under an elevated CO 2 concentration accelerate surface warming by reducing the surface albedo. In this study, we suggest that vegetation-atmosphere-sea ice interactions over high latitudes can induce an additional amplification of Arctic warming. Our hypothesis is tested by a series of coupled vegetation-climate model simulations under 2xCO 2 environments. The increased vegetation activities over high latitudes under a 2xCO 2 condition induce additional surface warming and turbulent heat fluxes to the atmosphere, which are transported to the Arctic through the atmosphere. This causes additional sea-ice melting and upper-ocean warming during the warm season. As a consequence, the Arctic and high-latitude warming is greatly amplified in the following winter and spring, which further promotes vegetation activities the following year. We conclude that the vegetation-atmosphere-sea ice interaction gives rise to additional positive feedback of the Arctic amplification. (letter)

  12. Vapor-liquid equilibrium of ethanol/ethyl acetate mixture in ultrasonic intensified environment

    Energy Technology Data Exchange (ETDEWEB)

    Mahdi, Taha; Ahmad, Arshad; Ripin, Adnan Nasef; Mohamed, Mahmoud [Universiti Teknologi Malaysia, Johor Bahru (Malaysia)

    2014-05-15

    A vapor-liquid equilibrium (VLE) study was conducted on ethanol/ethylacetate mixture as a preliminary step towards developing an ultrasonic-assisted distillation process for separating azeotropic mixtures. The influence of ultrasonic intensity and frequency on the vapor-liquid equilibrium (VLE) of the mixture was examined using a combination of four ultrasonic intensities in range of 100-400W/cm{sup 2} and three frequencies ranging from 25-68 kHz. The sonication was found to have significant impacts on the VLE of the system as it alters both the relative volatility and azeotrope point, with preference to lower frequency operation. A maximum relative volatility of 2.32 was obtained at an intensity of 300 W/cm{sup 2} and a frequency of 25 kHz coupled with complete elimination of ethanol-ethyl acetate azeotrope. Results from this work were also congruent with some experimental and theoretical works presented in the literature. These findings set a good beginning towards the development of an ultrasonic assisted distillation that is currently in progress.

  13. Evaluation of intensified behaviour change communication strategies in an artemisinin resistance setting.

    Science.gov (United States)

    Canavati, Sara E; de Beyl, Celine Zegers; Ly, Po; Shafique, Muhammad; Boukheng, Thavrin; Rang, Chandary; Whittaker, Maxine Anne; Roca-Feltrer, Arantxa; Sintasath, David

    2016-04-30

    In Cambodia, behaviour change communication (BCC) represents an integral component of malaria efforts aimed at fighting artemisinin resistant parasites and achieving elimination. The multi-pronged BCC interventions include interpersonal communication through village health volunteers (VHVs) and village malaria workers (VMWs), broadcasting malaria prevention, diagnosis and treatment messages via TV, radio and mobile broadcasting units (MBUs), distributing information education and communication (IEC) materials and introducing mobile malaria workers (MMWs) in endemic villages. This was a cross sectional household survey using a stratified multi-stage cluster sampling approach, conducted in December 2012. A stratified multi-stage cluster sampling approach was used; 30 villages were selected (15 in each stratum) and a total of 774 households were interviewed. This survey aimed to assess the potential added effect of 'intense' BCC interventions in three Western provinces. Conducted 2 years after start of these efforts, 'non-intense' BCC (niBBC) interventions (e.g., radio or TV) were compared to "intense" BCC (iBBC) implemented through a set of interpersonal communication strategies such as VMWs, VHVs, mobile broadcasting units and listener viewer clubs. In both groups, the knowledge of the mode of malaria transmission was high (96.9 vs 97.2 %; p = 0.83), as well as of fever as a symptom (91.5 vs 93.5 %; p = 0.38). Knowledge of local risk factors, such as staying in the forest (39.7 vs 30.7 %; p = 0.17) or the farm (7.1 vs 5.1 %; p = 0.40) was low in both groups. Few respondents in either group knew that they must get tested if they suspected malaria (0.3 vs 0.1; p = 0.69). However, iBBC increased the discussions about malaria in the family (51.7 vs 35.8 %; p = 0.002) and reported prompt access to treatment in case of fever (77.1 vs 59.4 %; p Strategic Plan in the Cambodia Malaria Elimination Action Framework (2016-2020). Therefore, this study provides evidence for the planning and implementation of future BCC interventions to achieve the elimination of artemisinin resistant Plasmodium falciparum malaria.

  14. Intensifying existing premix therapy (BIAsp 30) with BIAsp 50 and BIAsp 70

    DEFF Research Database (Denmark)

    Brito, Miguel; Ligthelm, Robert Jan; Boemi, Massimo

    2011-01-01

    In 2009, consensus guidelines were published on intensification of insulin therapy using the premix analog biphasic insulin aspart (BIAsp) 30 in the treatment of type 2 diabetes, based on the recommendations of an international, independent expert panel. The guidelines included recommendations an...... assist physicians in introducing mid-/high-ratio premixes to optimize the insulin therapy of patients with type 2 diabetes who are failing to achieve glycemic targets on a BIAsp 30 BID or TID regimen....

  15. Toward intensifying design of experiments in upstream bioprocess development: An industrial Escherichia coli feasibility study.

    Science.gov (United States)

    von Stosch, Moritz; Hamelink, Jan-Martijn; Oliveira, Rui

    2016-09-01

    In this study, step variations in temperature, pH, and carbon substrate feeding rate were performed within five high cell density Escherichia coli fermentations to assess whether intraexperiment step changes, can principally be used to exploit the process operation space in a design of experiment manner. A dynamic process modeling approach was adopted to determine parameter interactions. A bioreactor model was integrated with an artificial neural network that describes biomass and product formation rates as function of varied fed-batch fermentation conditions for heterologous protein production. A model reliability measure was introduced to assess in which process region the model can be expected to predict process states accurately. It was found that the model could accurately predict process states of multiple fermentations performed at fixed conditions within the determined validity domain. The results suggest that intraexperimental variations of process conditions could be used to reduce the number of experiments by a factor, which in limit would be equivalent to the number of intraexperimental variations per experiment. © 2016 American Institute of Chemical Engineers Biotechnol. Prog., 32:1343-1352, 2016. © 2016 American Institute of Chemical Engineers.

  16. Evidence of intensified biogenic silica recycling in the Black Sea after 1970

    DEFF Research Database (Denmark)

    Mousing, Erik Askov; Adjou, Mohamed; Ellegaard, Marianne

    2015-01-01

    140 years and show that siliceous protists became significantly more dissolved after the late 1960s indicating a reduction of the silicate pool preserved in the deep sea sediment. We hypothesize that the decline in the dissolution state is caused by increased recycling of biogenic silica in the water...

  17. Interannual variation of the South China Sea circulation during winter: intensified in the southern basin

    Science.gov (United States)

    Zu, Tingting; Xue, Huijie; Wang, Dongxiao; Geng, Bingxu; Zeng, Lili; Liu, Qinyan; Chen, Ju; He, Yunkai

    2018-05-01

    Surface geostrophic current derived from altimetry remote sensing data, and current profiles observed from in-situ Acoustic Doppler Current Profilers (ADCP) mooring in the northern South China Sea (NSCS) and southern South China Sea (SSCS) are utilized to study the kinetic and energetic interannual variability of the circulation in the South China Sea (SCS) during winter. Results reveal a more significant interannual variation of the circulation and water mass properties in the SSCS than that in the NSCS. Composite ananlysis shows a significantly reduced western boundary current (WBC) and a closed cyclonic eddy in the SSCS at the mature phase of El Niño event, but a strong WBC and an unclosed cyclonic circulation in winter at normal or La Niña years. The SST is warmer while the subsurface water is colder and fresher in the mature phase of El Niño event than that in the normal or La Niña years in the SSCS. Numerical experiments and energy analysis suggest that both local and remote wind stress change are important for the interannual variation in the SSCS, remote wind forcing and Kuroshio intrusion affect the circulation and water mass properties in the SSCS through WBC advection.

  18. Psychological contract breach and work performance: Is social exchange a buffer or an intensifier?

    NARCIS (Netherlands)

    Bal, P.M.; Chiaburu, D.S.; Jansen, P.G.W.

    2010-01-01

    Purpose: The aim of this paper is to investigate how social exchanges modify the relationship between psychological contract breach and work performance. It aims to present two concurrent hypotheses, based on theoretical interaction effects of social exchanges (conceptualized as social exchange

  19. A study on intensifying efficiency for international collaborative development of advanced nuclear energy technology

    Energy Technology Data Exchange (ETDEWEB)

    Lee, J. H.; Hahn, D. H.; Song, K. C.; Chang, J. H.; Kim, H. J.; Kim, H. J.; Lim, C. Y.; Lee, D. S.; Lee, Y. J. [KAERI, Daejeon (Korea, Republic of)

    2011-03-15

    The objective of the study was to participate the GIF for the efficient propulsion of future nuclear system development. For achieving the objective of this study, the followings were carried out. {Omicron} Analyze the international/domestic trends in the future nuclear energy system {Omicron} Analyze the domestic long-term R and D program for the future nuclear system and assist its implementation - Review the agenda of the executive committee, the technical committee, and sub-technical committee - Assist the committee meetings and workshops related to the future nuclear energy system {Omicron} Develop the participation strategy for the collaborative development of Gen-IV technology and conducting the international cooperation activities - Support the delegation by reviewing the agenda of GIF meetings in the technical and legal perspective - Research the system R and D arrangement and report its progress - Participate in the SFR SIA PA negotiation meeting and report its progress {Omicron} Support the activities related to I-NERI between Korea and U.S. - Support a delegation by reviewing the agenda in the technical/legal point of view - Participate in the BINERIC meetings and Support the related activities The result of this study may be used for 1) contribution to establishing the effective foundation and broadening the cooperation activities between the advanced countries and Korea and 2) contribution effective management of Gen IV international collaboration by technical/legal supporting

  20. Intensified water storage loss by biomass burning in Kalimantan: Detection by GRACE

    Science.gov (United States)

    Han, Jiancheng; Tangdamrongsub, Natthachet; Hwang, Cheinway; Abidin, Hasanuddin Z.

    2017-03-01

    Biomass burning is the principal tool for land clearing and a primary driver of land use change in Kalimantan (the Indonesian part of Borneo island). Biomass burning here has consumed millions of hectares of peatland and swamp forests. It also degrades air quality in Southeast Asia, perturbs the global carbon cycle, threatens ecosystem health and biodiversity, and potentially affects the global water cycle. Here we present the optimal estimate of water storage changes over Kalimantan from NASA's Gravity Recovery and Climate Experiment (GRACE). Over August 2002 to December 2014, our result shows a north-south dipole pattern in the long-term changes in terrestrial water storage (TWS) and groundwater storage (GWS). Both TWS and GWS increase in the northern part of Kalimantan, while they decrease in the southern part where fire events are the most severe. The loss rates in TWS and GWS in the southern part are 0.56 ± 0.11 cm yr-1 and 0.55 ± 0.10 cm yr-1, respectively. We use GRACE estimates, burned area, carbon emissions, and hydroclimatic data to study the relationship between biomass burning and water storage losses. The analysis shows that extensive biomass burning results in excessive evapotranspiration, which then increases long-term water storage losses in the fire-prone region of Kalimantan. Our results show the potentials of GRACE and its follow-on missions in assisting water storage and fire managements in a region with extensive biomass burning such as Kalimantan.

  1. Amination of Aryl Halides and Esters Using Intensified Continuous Flow Processing

    Directory of Open Access Journals (Sweden)

    Thomas M. Kohl

    2015-09-01

    Full Text Available Significant process intensification of the amination reactions of aryl halides and esters has been demonstrated using continuous flow processing. Using this technology traditionally difficult amination reactions have been performed safely at elevated temperatures. These reactions were successfully conducted on laboratory scale coil reactor modules with 1 mm internal diameter (ID and on a preparatory scale tubular reactor with 6 mm ID containing static mixers.

  2. A Study on intensifying efficiency for international collaborative development of Advanced Nuclear Energy Technology

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Moon Hee; Kim, H. R.; Kim, H. J.; Chang, J. H.; Hahn, D. H.; Bae, Y. Y.; Kim, W. W.; Jeong, I.; Lee, D. S.; Lee, J. H. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2008-06-15

    Generation IV International Forum(GIF), where 13 countries including Korea collaborate to develop future nuclear energy systems, put into force 'Generation IV International Forum Project Arrangement' in 2007 for the international research and development of Gen IV Systems, following the entry into force of Framework Agreement in 2005. The International Nuclear Research Initiative(I-NERI) between Korea and United States and the International Project on Innovative Nuclear Energy Systems and Fuel Cycles(INPRO) of IAEA are continued in this year, produced lots of visible outcomes. These international activities have a common goal of the collaborative development of advanced nuclear system technologies but differ in the main focusing areas and aspects, so Korea needs to establish the integrated strategy based on the distinguished and complementary approach for the participation of each international programs, as examples the GIF for the advanced system technology development, INPRO for the set-up of institution and infra-structure, and I-NERI for the access of the core technologies and acquisition of the transparency of nuclear R and D.

  3. Future equivalent of 2010 Russian heatwave intensified by weakening soil moisture constraints

    NARCIS (Netherlands)

    Rasmijn, L.M.; Schrier, van der G.; Bintanja, R.; Barkmeijer, J.; Sterl, A.; Hazeleger, W.

    2018-01-01

    The 2010 heatwave in eastern Europe and Russia ranks among the hottest events ever recorded in the region1,2. The excessive summer warmth was related to an anomalously widespread and intense quasi-stationary anticyclonic circulation anomaly over western Russia, reinforced by depletion of spring soil

  4. Rising CO2 levels will intensify phytoplankton blooms in eutrophic and hypertrophic lakes.

    Directory of Open Access Journals (Sweden)

    Jolanda M H Verspagen

    Full Text Available Harmful algal blooms threaten the water quality of many eutrophic and hypertrophic lakes and cause severe ecological and economic damage worldwide. Dense blooms often deplete the dissolved CO2 concentration and raise pH. Yet, quantitative prediction of the feedbacks between phytoplankton growth, CO2 drawdown and the inorganic carbon chemistry of aquatic ecosystems has received surprisingly little attention. Here, we develop a mathematical model to predict dynamic changes in dissolved inorganic carbon (DIC, pH and alkalinity during phytoplankton bloom development. We tested the model in chemostat experiments with the freshwater cyanobacterium Microcystis aeruginosa at different CO2 levels. The experiments showed that dense blooms sequestered large amounts of atmospheric CO2, not only by their own biomass production but also by inducing a high pH and alkalinity that enhanced the capacity for DIC storage in the system. We used the model to explore how phytoplankton blooms of eutrophic waters will respond to rising CO2 levels. The model predicts that (1 dense phytoplankton blooms in low- and moderately alkaline waters can deplete the dissolved CO2 concentration to limiting levels and raise the pH over a relatively wide range of atmospheric CO2 conditions, (2 rising atmospheric CO2 levels will enhance phytoplankton blooms in low- and moderately alkaline waters with high nutrient loads, and (3 above some threshold, rising atmospheric CO2 will alleviate phytoplankton blooms from carbon limitation, resulting in less intense CO2 depletion and a lesser increase in pH. Sensitivity analysis indicated that the model predictions were qualitatively robust. Quantitatively, the predictions were sensitive to variation in lake depth, DIC input and CO2 gas transfer across the air-water interface, but relatively robust to variation in the carbon uptake mechanisms of phytoplankton. In total, these findings warn that rising CO2 levels may result in a marked intensification of phytoplankton blooms in eutrophic and hypertrophic waters.

  5. Evaluation of intensified prehospital treatment in out-of-hospital cardiac arrest

    DEFF Research Database (Denmark)

    Frandsen, F; Nielsen, J R; Gram, L

    1991-01-01

    During a period of 3 years three different types of emergency medical service (EMS) systems were evaluated in a city with about 238,000 inhabitants/population density of 570/km2. Included were 393 out-of-hospital cardiac arrest patients in whom prehospital cardiopulmonary resuscitation was provid...... survive and the more patients survive with good cerebral function. However, the ambulances with specially trained paramedics were only effective in the area with 340 inhabitants/km2....

  6. A Study on intensifying efficiency for international collaborative development of Advanced Nuclear Energy Technology

    Energy Technology Data Exchange (ETDEWEB)

    Hahn, Dohee; Park, Seongwon; Chang, Moonhee

    2013-08-15

    All the countries of the world are promoting the use of atomic energy to provide against high oil prices, climatic changes, and energy security initiative. A domestic and foreign environment for nuclear energy is changing rapidly and 13 leading countries including Korea are trying to develop advanced technologies on Gen IV nuclear energy system through Gen IV International Forum (GIF). To enhance the effectiveness of the future nuclear energy system development plan, a strategic approach is necessary for GIF program and the connection process with the 4th Nuclear Energy Promotion Program and Nuclear Energy R and D Medium and Long Term 5 year Plan for 2012 ∼ 2016 needs to be prepared. This study was to analyze the global nuclear trends of 2012 and the status of GIF program which is international cooperation activities. Also we examined the domestic R and D status of future nuclear energy systems for developing core technology and commercialization of Gen-IV nuclear energy system. A successful performance of this project enables the effective national cooperation with GIF and promotes the public acceptance by suggesting the technical alternatives for the nuclear safety and the spent fuel management.

  7. Biological Maturity Status Strongly Intensifies the Relative Age Effect in Alpine Ski Racing.

    Directory of Open Access Journals (Sweden)

    Lisa Müller

    Full Text Available The relative age effect (RAE is a well-documented phenomenon in youth sports. This effect exists when the relative age quarter distribution of selected athletes shows a biased distribution with an over-representation of relatively older athletes. In alpine ski racing, it exists in all age categories (national youth levels up to World Cup. Studies so far could demonstrate that selected ski racers are relatively older, taller and heavier. It could be hypothesized that relatively younger athletes nearly only have a chance for selection if they are early maturing. However, surprisingly this influence of the biological maturity status on the RAE could not be proven, yet. Therefore, the aim of the present study was to investigate the influence of the biological maturity status on the RAE in dependence of the level of competition. The study investigated 372 elite youth ski racers: 234 provincial ski racers (P-SR; high level of competition and 137 national ski racers (N-SR; very high level of competition. Anthropometric characteristics were measured to calculate the age at peak height velocity (APHV as an indicator of the biological maturity status. A significant RAE was present among both P-SR and N-SR, with a larger effect size among the latter group. The N-SR significantly differed in APHV from the P-SR. The distribution of normal, early and late maturing athletes significantly differed from the expected normal distribution among the N-SR, not among the P-SR. Hardly any late maturing N-SR were present; 41.7% of the male and 34% of the female N-SR of the last relative age quarter were early maturing. These findings clearly demonstrate the significant influence of the biological maturity status on the selection process of youth alpine ski racing in dependence of the level of competition. Relatively younger athletes seem to have a chance of selection only if they are early maturing.

  8. Radiation safety evaluation of a hand-held, battery operated image intensifier

    International Nuclear Information System (INIS)

    Wilson, O.J.; Young, B.F.

    1987-01-01

    A portable, hand-held, fluoroscopic unit intended for medical and industrial use was tested to verify the claim of the manufacturers that the radiation doses to the patient and user are low, and comparable to those received from standard radiographic procedures. The first claim was substantiated but not the second. A number of concerns arising from the use of this unit are discussed

  9. A Study on intensifying efficiency for international collaborative development of Advanced Nuclear Energy Technology

    International Nuclear Information System (INIS)

    Chang, Moon Hee; Kim, H. R.; Kim, H. J.

    2009-08-01

    The objective of the study was to participate the GIF for the efficient propulsion of future nuclear system development. For achieving the objective of this study, the followings were carried out. · Investigation and analysis of the international and domestic trends related to future nuclear system · To maximize the national interests by the strategic participation of GIF meeting - To participate of GIF meeting and to support of relative work - To investigate the System R and D Arrangement and to inform its progress situation · To maximize the propulsion results of Korea/U.S nuclear energy joint research(I-NERI) - To support a delegation by the review of agenda in aspect of the technical/legal point - To participate of BINERIC meeting and to support of relative work · Streamline the nuclear energy R and D due to the effective connection between domestic R and D and international collaboration The result of this study may be used for 1) contribution to establishing the effective foundation and broadening the cooperation activities between the advanced countries and Korea and 2) contribution effective management of Gen IV international collaboration by technical/legal supporting

  10. Motivation within Role-Playing as a Means to Intensify College Students' Educational Activity

    Science.gov (United States)

    Burenkova, Olga Mikhailovna; Arkhipova, Irina Vladimirovna; Semenov, Sergei Aleksandrovich; Samarenkina, Saniya Zakirzyanovna

    2015-01-01

    This article covers college students' educational activity issues while studying a foreign language; analyzes special aspects of motivation introduction, their specific features. It also defines role and structure of role-playing. The authors come to the conclusion that introduction of role-playing in an educational process will bring it closer to…

  11. Fire propagation over combustible exterior facades exposed to intensified flame in Japan

    Directory of Open Access Journals (Sweden)

    Nishio Yuhei

    2016-01-01

    Full Text Available With regard to fire safety for exterior walls of a building, fire-resistance performance is considered, according to the current Building Standard Law of Japan. And it was revealed that the fire safety is not specifically regulated from the viewpoint of reaction-to-fire performance, such as fire propagation caused by combustible materials or products installed on the exterior side of fire-resistant load-bearing walls. Actual fire incidents in the world have shown that massive façade fire could occur at the exterior side of building wall even when the wall itself is fire resistant. In previous studies of the authors, a test method of façade fire was proposed for evaluating the vertical fire propagation over an external wall within the same building [1,2]. Based on these studies, new domestic standard test method was established in Japan as JIS A 1310: 2015, “Test method for fire propagation over building façades” at the end of January 2015 [3]. But there was the argument that heat output of burner inside the combustion chamber was not sufficiently high in the previous study. In this paper, results of fire tests on combustible façades are discussed from the viewpoints of different strength of flame exposing facade. In this research, it was clearly found that JIS A 1310 with heat output of 900kW could be applicable for evaluating fire propagation behaviour over various types of combustible exterior façades.

  12. Palaeotethys seawater temperature rise and an intensified hydrological cycle following the end-Permian mass extinction

    DEFF Research Database (Denmark)

    Schobben, Martin; Joachimski, Michael M.; Korn, Dieter

    2014-01-01

    are presented together with new data from Wuchiapingian to Griesbachian sections in Iran. δ18O data from P-Tr sections in Iran document tropical sea surface temperatures (SST) of 27-33°C during the Changhsingian with a negative shift in δ18O starting at the extinction horizon, translating into a warming of SSTs...... and associated processes, vertical water column stratification, eutrophication and subsequent local anoxia may all have facilitated an extinction event....

  13. Temporary agency work, migration and the crisis in Greece: labour market segmentation intensified.

    Science.gov (United States)

    Maroukis, Thanos

    2016-05-01

    This article focuses on the under-researched temporary agency employment in Greece. It shows that the development of the temporary employment agency sector has gone hand in hand with the flow of undocumented and exploitable migrant labour in Greece over the past 25 years, reflecting the segmentation of the Greek labour market along ethnic lines. Using empirical research evidence on the operation of temporary employment agencies in the Greek hospitality and health care sectors, the article highlights the precarious or even illicit nature of agency employment in a context in which labour outsourcing and flexible employment are promoted by policy-makers. Last but not least, it suggests that the segmented landscape of the Greek labour market has become more complex during the economic crisis, with more and more Greeks drawn to agency-mediated precarious employment.

  14. Teaching China in Scotland's Secondary Schools as Sino-Scottish Engagement Intensifies

    Science.gov (United States)

    Oates, John Vincent

    2011-01-01

    At a time of burgeoning Sino-Scottish engagement, and the introduction of a new national education policy, "Curriculum for Excellence" designed to enhance teacher autonomy, this paper draws on the national response of Modern Studies teachers who are the only group of Scottish teachers to have the (voluntary) option of including the study…

  15. Temporary agency work, migration and the crisis in Greece: labour market segmentation intensified

    Science.gov (United States)

    2016-01-01

    This article focuses on the under-researched temporary agency employment in Greece. It shows that the development of the temporary employment agency sector has gone hand in hand with the flow of undocumented and exploitable migrant labour in Greece over the past 25 years, reflecting the segmentation of the Greek labour market along ethnic lines. Using empirical research evidence on the operation of temporary employment agencies in the Greek hospitality and health care sectors, the article highlights the precarious or even illicit nature of agency employment in a context in which labour outsourcing and flexible employment are promoted by policy-makers. Last but not least, it suggests that the segmented landscape of the Greek labour market has become more complex during the economic crisis, with more and more Greeks drawn to agency-mediated precarious employment. PMID:27499601

  16. Intensify dodecylamine adsorption on magnesite and dolomite surfaces by monohydric alcohols

    Science.gov (United States)

    Zhang, Hao; Liu, Wengang; Han, Cong; Wei, Dezhou

    2018-06-01

    The flotation of magnesite and dolomite were investigated with the presence of single dodecylamine (DDA) and combined mixtures of DDA and monohydric alcohols, respectively. The adsorption behavior of DDA, butanol, hexanol and octanol on the surface of the two minerals were shown by molecular dynamics simulation, and the results were corresponding with the analysis of zeta potential, measurements of the contact angle and adsorption. Flotation results indicated that part of DDA could be replaced by the three alcohols (butanol, hexanol, octanol) to get better flotation results. Molecular dynamics simulation and the results of zeta potential and contact angle measurements indicated that adsorption of DDA on mineral surfaces could be strengthened by monohydric alcohols.

  17. Apllication of plastic scintillators with light intensifiers in photographic dosemeters to increase the sensitivity

    International Nuclear Information System (INIS)

    Mesquita, C.H. de; Hamada, M.M.

    1988-01-01

    The purpose of this work is to evaluate the effect of a light converter (plastic scintillator) to use as badge in the conventional photographic dosimeter. In this dosimeter the light is a new component of emulsion sensibilization. So, even radiations that are not able to reach the photographic emulsion can be detected by producing photons in the plastic scintillator. (author) [pt

  18. Development of radiophotometric dosemeters of high sensitivity using plastic scintillators as light intensifiers

    International Nuclear Information System (INIS)

    Mesquita, C.H. de; Hamada, M.M.

    1987-01-01

    The use of rectangular plates of plastic scintillators as film holders in conventional photographic dosemeters is reported. The efficiency of their use as light converters for increase the sensitivity of these dosemeters are studied. (M.A.C.) [pt

  19. Development of radiophotometric dosemeters with high sensitivity using plastic scintillators as a light intensifier

    International Nuclear Information System (INIS)

    Mesquita, C.H. de; Hamada, M.M.

    1987-01-01

    Rectangular plates of plastic scintillators are developed and their effect as light converter evaluated, when used as film-holder in conventional photography dosemeters. In this dosemeter, the radiation that not interacts in the photographic film can be detected by light photons generation in the plastic scintillators, sensitizing the film. (C.G.C.) [pt

  20. Why Do Model Tropical Cyclones Intensify More Rapidly at Low Latitudes?

    Science.gov (United States)

    2015-05-01

    University of Munich, Munich, Germany MICHAEL T. MONTGOMERY Department of Meteorology, Naval Postgraduate School , Monterey, California (Manuscript...WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School ,Department of Meteorology,Monterey,CA,93943 8...Roy.Meteor. Soc., 135, 839–850, doi:10.1002/qj.390. Willoughby, H. E., 1979: Forced secondary circulations in hurri- canes . J. Geophys. Res., 84, 3173

  1. Parents' and Adolescents' Preferences for Intensified or Reduced Treatment in Randomized Lymphoblastic Leukemia Trials

    DEFF Research Database (Denmark)

    Tulstrup, Morten; Larsen, Hanne Bækgaard; Castor, Anders

    2015-01-01

    compared to younger children in trials with different toxicity profiles. PROCEDURE: Age-dependent participation rates in three consecutive, randomized childhood leukemia trials conducted by the Nordic Society of Paediatric Haematology and Oncology were evaluated. The ALL2000 dexamethasone/vincristine (Dx...... prospectively registered by the treating physicians. RESULTS: Parents of young children favored treatment intensifications (Dx/VCR: 12% refusal; 6MP: 14%; ASP: 21%), whereas parents of adolescents favored treatment reductions (Dx/VCR: 52% refusal; 6MP: 30%; ASP: 8%). Adolescents were more likely to refuse...... intensification trials than young children (adjusted ORs 6.3; P treatment (adjusted OR for median consolidation length 0.15; P = 0...

  2. Ultrafast gated intensifier design for laser fusion x-ray framing applications

    International Nuclear Information System (INIS)

    Price, R.H.; Wiedwald, J.D.; Kalibjian, R.; Thomas, S.W.; Cook, W.M.

    1983-01-01

    A major challenge for laser fusion is the study of the symmetry and the hydrodynamic stability of imploding fuel capsules. Streaked x-radiography, in one space and one time dimension, does not provide sufficient information. Two (spatial) dimensional frames of 10 to 100 ps duration are required with good image quality, minimum geometrical distortion (approximately 1%), dynamic range greater than 1000 and greater than 200 x 200 pixels. A gated transmission line imager (TLI) can meet these requirements with frame times between 30 and 100 ps. An instrument of this type is now being developed. Progress on this instrument including theory of operation, ultrafast pulse generation and propagation, component integration, and high resolution phosphor screen development are presented

  3. HIV/AIDS and auditory function in adults: the need for intensified ...

    African Journals Online (AJOL)

    It begins with an introduction to the effects of HIV disease and treatment on the auditory system, and so highlights the need to put auditory function in adults with HIV or AIDS on the healthcare and research agenda in developing countries. The discussion refers to this population in regard to: published prevalence and ...

  4. A Study on intensifying efficiency for international collaborative development of Advanced Nuclear Energy Technology

    International Nuclear Information System (INIS)

    Chang, Moon Hee; Kim, H. R.; Kim, H. J.; Chang, J. H.; Hahn, D. H.; Bae, Y. Y.; Kim, W. W.; Jeong, I.; Lee, D. S.; Lee, J. H.

    2008-06-01

    Generation IV International Forum(GIF), where 13 countries including Korea collaborate to develop future nuclear energy systems, put into force 'Generation IV International Forum Project Arrangement' in 2007 for the international research and development of Gen IV Systems, following the entry into force of Framework Agreement in 2005. The International Nuclear Research Initiative(I-NERI) between Korea and United States and the International Project on Innovative Nuclear Energy Systems and Fuel Cycles(INPRO) of IAEA are continued in this year, produced lots of visible outcomes. These international activities have a common goal of the collaborative development of advanced nuclear system technologies but differ in the main focusing areas and aspects, so Korea needs to establish the integrated strategy based on the distinguished and complementary approach for the participation of each international programs, as examples the GIF for the advanced system technology development, INPRO for the set-up of institution and infra-structure, and I-NERI for the access of the core technologies and acquisition of the transparency of nuclear R and D

  5. Intensified photodynamic therapy of actinic keratoses with fractional CO2 laser

    DEFF Research Database (Denmark)

    Togsverd-Bo, K; Haak, C S; Thaysen-Petersen, D

    2012-01-01

    Photodynamic therapy (PDT) with methyl aminolaevulinate (MAL) is effective for thin actinic keratoses (AKs) in field-cancerized skin. Ablative fractional laser resurfacing (AFXL) creates vertical channels that facilitate MAL uptake and may improve PDT efficacy....

  6. Intensified process for aromatics separation powered by Kaibel and dividing-wall columns

    NARCIS (Netherlands)

    Kiss, A.A.; Ignat, R.M.; Flores Landaeta, S.J.; Haan, de A.B.

    2013-01-01

    Process intensification in distillation led to major developments, such as reactive distillation, heat-integrated distillation, cyclic distillation, as well as Kaibel and dividing-wall column. Still, the separation of aromatics at industrial scale is carried out typically in a series of conventional

  7. Intensified tuberculosis case finding among malnourished children in nutritional rehabilitation centres of Karnataka, India: missed opportunities.

    Directory of Open Access Journals (Sweden)

    Prashant G Bhat

    Full Text Available BACKGROUND: Severe acute malnutrition (SAM is the most serious form of malnutrition affecting children under-five and is associated with many infectious diseases including Tuberculosis (TB. In India, nutritional rehabilitation centres (NRCs have been recently established for the management of SAM including TB. The National TB Programme (NTP in India has introduced a revised algorithm for diagnosing paediatric TB. We aimed to examine whether NRCs adhered to these guidelines in diagnosing TB among SAM children. METHODS: A cross-sectional study involving review of records of all SAM children identified by health workers during 2012 in six tehsils (sub-districts with NRCs (population: 1.8 million of Karnataka, India. RESULTS: Of 1927 identified SAM children, 1632 (85% reached NRCs. Of them, 1173 (72% were evaluated for TB and 19(2% were diagnosed as TB. Of 1173, diagnostic algorithm was followed in 460 (37%. Among remaining 763 not evaluated as per algorithm, tuberculin skin test alone was conducted in 307 (41%, chest radiography alone in 99 (13% and no investigations in 337 (45%. The yield of TB was higher among children evaluated as per algorithm (4% as compared to those who were not (0.3% (OR: 15.3 [95%CI: 3.5-66.3]. Several operational challenges including non-availability of a full-time paediatrician, non-functioning X-ray machine due to frequent power cuts, use of tuberculin with suboptimal strength and difficulties in adhering to a complex diagnostic algorithm were observed. CONCLUSION: This study showed that TB screening in NRCs was sub-optimal in Karnataka. Some children did not reach the NRC, while many of those who did were either not or sub-optimally evaluated for TB. This study pointed to a number of operational issues that need to be addressed if this collaborative strategy is to identify more TB cases amongst malnourished children in India.

  8. Digital image intensifier radiography: first experiences with the DSI (Digital Spot Imaging)

    International Nuclear Information System (INIS)

    Rueckforth, J.; Wein, B.; Stargardt, A.; Guenther, R.W.

    1995-01-01

    We performed a comparative study of digitally and conventionally acquired images in gastrointestinal examinations. Radiation dose and spatial resolution were determined in a water phantom. In 676 examinations with either conventional or digital imaging (system: Diagnost 76, DSI) the number of images and the duration of the fluoroscopy time were compared. 101 examinations with digital as well as conventional documentation were evaluated by using 5 criteria describing the diagnostic performance. The entrance dose of the DSI is 12% to 36% of the film/screen system and the spatial resolution of the DSI may be better than that of a film/screen system with a speed of 200. The fluoroscopy time shows no significant difference between DSI and the film/screen technique. In 2 of 4 examination modes significantly more images were produced by the DSI. With exception of the criterion of edge sharpness, DSI yields a significantly inferior assessment compared with the film/screen technique. (orig./MG) [de

  9. Unhappiness Intensifies the Avoidance of Frequent Losses While Happiness Overcomes It.

    Science.gov (United States)

    Yechiam, Eldad; Telpaz, Ariel; Krupenia, Stas; Rafaeli, Anat

    2016-01-01

    The implication of spontaneous and induced unhappiness to people's decision style is examined. It is postulated that unhappy individuals have a greater tendency to avoid frequent losses because these can have depleting effects, and unhappy individuals are more sensitive to such effects. This is evaluated in Study 1 by using an annoying customer call manipulation to induce negative affect; and by examining the effect of this manipulation on choices in an experiential decision task (the Iowa Gambling task). In Study 2 we examined the association between self-reported (un)happiness and choices on the same decision task. In Study 1 the induction of negative affect led to avoidance of choice alternatives with frequent losses, compared to those yielding rarer but larger losses. Specifically, this pertained to the advantageous alternatives with frequent vs. non-frequent losses. In Study 2 unhappiness was similarly associated with less exposure to frequent losses; while extreme high happiness was associated with no tendency to avoid frequent losses when these were part of an advantageous alternative. The findings clarify the role of happiness in decision making processes by indicating that unhappiness induces sensitivity to the frequency rather than to the total effect of negative events.

  10. Application of Image Intensifier Technology to the Military, Scientific, Industrial, Educational, and Medical Communities.

    Science.gov (United States)

    1980-05-30

    Method of Study ...... ................ .20 Interview Procedures ..... ............. 21 Limitations ....... .................. .21 Method of Analysis ...device was compact, passive, and could improve visibil- ity during periodslof low light levels of illumination by amplifying the point moon ( moonlight ) and...photography equipment where controls are required to prevent excessive fogging of film 7 during long exposures. Closely behind the introduction of the image

  11. Bioenergy and biodiversity: Intensified biomass extraction from hedges impairs habitat conditions for birds.

    Science.gov (United States)

    Sauerbrei, Ralf; Aue, Birgit; Krippes, Christian; Diehl, Eva; Wolters, Volkmar

    2017-02-01

    Biomass is increasingly used as an alternative source for energy in Europe. Woody material cut from hedges is considered to provide a suitable complement to maize and oilseed rape, which are currently the dominant biomass sources. Since shrubs and trees are also important habitats for birds, however, coppicing of hedges at the landscape scale may adversely affect the diversity of the avifauna. To evaluate this risk, we estimated the response of hedge birds to three management scenarios differing in cutting intensity and hedge selection. The analysis was done using hedge data of the Lautertal municipality (n = 339 hedges; Vogelsberg area, Hesse, Germany). It focused on 25 bird species, which are all listed in the hedge programme of the German Ornithological Stations. Information on the preferences of these birds for certain hedge features such as height or width was gathered by an extensive literature review. A cluster analysis on the consolidated literature data allowed us to identify three groups of birds according to their preference for certain hedge attributes. Two groups, which included Yellowhammer (Emberiza citrinella L.) (i) and Blackbird (Turdus merula L.) (ii), favoured trees located in hedges, but differed in their preference for hedge shape, with (i) being attracted by long and broad hedges and (ii) by high hedges. The third group, which included the Whitethroat (Sylvia communis L.), preferred small hedges with gaps and medium vegetation density. Spatially explicit suitability models based on these data allowed us to predict the status quo of hedge suitability for these species groups. Field surveys proved the accuracy of the predictions to be sufficient, since the hedge suitability predicted was significantly and positively correlated to the occurrence of 9 out of the 12 testable focal species. Our models predicted biomass extraction to almost always reduce hedge suitability for the three bird groups. Concerning the Yellowhammer and the Blackbird group, a high level of biomass extraction reduced hedge suitability by approximately 20%. We thus conclude that intensively extracting biomass can significantly reduce hedge suitability for birds, despite considerable differences in habitat requirements. Considering the variable response of the bird groups to our scenarios as well as the variation in habitat occupancy by birds, however, cutting woody material from hedges nevertheless provides an option to reduce adverse effects of bioenergy production on biodiversity at the landscape scale, as long as hedge management is based on the best knowledge available. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Cassava and soil fertility in intensifying smallholder farming systems of East Africa

    NARCIS (Netherlands)

    Fermont, van A.M.

    2009-01-01

    Keywords: Cost-benefits, Crop management, Farming systems, Fertilizer, Food security, Generalizations, Income, Labour, Land pressure, Niche, Rainfall, Sub-Saharan Africa, System analysis, Yield gap.
    Cassava is an important crop in Africa. This thesis focuses on cassava production in the mid

  13. Rising CO2 Levels Will Intensify Phytoplankton Blooms in Eutrophic and Hypertrophic Lakes

    Science.gov (United States)

    Verspagen, Jolanda M. H.; Van de Waal, Dedmer B.; Finke, Jan F.; Visser, Petra M.; Van Donk, Ellen; Huisman, Jef

    2014-01-01

    Harmful algal blooms threaten the water quality of many eutrophic and hypertrophic lakes and cause severe ecological and economic damage worldwide. Dense blooms often deplete the dissolved CO2 concentration and raise pH. Yet, quantitative prediction of the feedbacks between phytoplankton growth, CO2 drawdown and the inorganic carbon chemistry of aquatic ecosystems has received surprisingly little attention. Here, we develop a mathematical model to predict dynamic changes in dissolved inorganic carbon (DIC), pH and alkalinity during phytoplankton bloom development. We tested the model in chemostat experiments with the freshwater cyanobacterium Microcystis aeruginosa at different CO2 levels. The experiments showed that dense blooms sequestered large amounts of atmospheric CO2, not only by their own biomass production but also by inducing a high pH and alkalinity that enhanced the capacity for DIC storage in the system. We used the model to explore how phytoplankton blooms of eutrophic waters will respond to rising CO2 levels. The model predicts that (1) dense phytoplankton blooms in low- and moderately alkaline waters can deplete the dissolved CO2 concentration to limiting levels and raise the pH over a relatively wide range of atmospheric CO2 conditions, (2) rising atmospheric CO2 levels will enhance phytoplankton blooms in low- and moderately alkaline waters with high nutrient loads, and (3) above some threshold, rising atmospheric CO2 will alleviate phytoplankton blooms from carbon limitation, resulting in less intense CO2 depletion and a lesser increase in pH. Sensitivity analysis indicated that the model predictions were qualitatively robust. Quantitatively, the predictions were sensitive to variation in lake depth, DIC input and CO2 gas transfer across the air-water interface, but relatively robust to variation in the carbon uptake mechanisms of phytoplankton. In total, these findings warn that rising CO2 levels may result in a marked intensification of phytoplankton blooms in eutrophic and hypertrophic waters. PMID:25119996

  14. CASE METHOD AS A MEANS TO INTENSIFY THE EDUCATIONAL PROCESS OF INTENDING ECONOMISTS

    Directory of Open Access Journals (Sweden)

    Олександр Вашків

    2014-04-01

    Full Text Available The article presents practical aspects of case-method usage in the process of researching social responsibility of business. The paper also gives a detailed insight into a situational exercise on the level of its constituting elements. Case-method has been characterized in terms of its peculiarities and the advantages, and in comparison to the traditional teaching methods. This article also presents a scenario of a situational exercise «Our daily bread», which has been prepared as a result of authors’ participation in the state programme «the Ukrainian Initiative», which presupposed training at the enterprises in Germany.

  15. Intensifying the intrinsic motivation by differentiating the teaching strategies in higher education

    Directory of Open Access Journals (Sweden)

    Tulbure, C.

    2011-01-01

    Full Text Available Learning motivation represents one of the most importantpredictors of academic achievement in higher education. In this empirical study, we have implemented a formative program to improve the university students’ academic achievement and their intrinsic learning motivation. To fully use their intellectual potential, students were treated according to their learning style, throughout one academic year. When we considered the within subject design, both intrinsic motivation and academic achievement significantly increased at the end of the study. Only intrinsic motivation proved to be significantly higher for the between subject comparison. Because our formative program proved to have a significant impact on students’ learning motivation, we recommend the differentiated teaching strategies to improve the academic achievement in higher education.

  16. Psychological contract breach and work performance:Is social exchange a buffer or an intensifier?

    OpenAIRE

    Bal, P. Matthijs; Chiaburu, Dan S.; Jansen, Paul G. W.

    2010-01-01

    Purpose: The aim of this paper is to investigate how social exchanges modify the relationship between psychological contract breach and work performance. It aims to present two concurrent hypotheses, based on theoretical interaction effects of social exchanges (conceptualized as social exchange relationships, POS, and trust). Design/methodology/approach: Data were collected from a sample of 266 employees in a service sector company in the USA. Regression analysis was used to explore the moder...

  17. Maternal high-fat diet intensifies the metabolic response to stress in male rat offspring

    OpenAIRE

    Karbaschi, Roxana; Zardooz, Homeira; Khodagholi, Fariba; Dargahi, Leila; Salimi, Mina; Rashidi, FatemehSadat

    2017-01-01

    Background The mother?s consumption of high-fat food can affect glucose metabolism and the hypothalamic?pituitary?adrenal axis responsiveness in the offspring and potentially affect the metabolic responses to stress as well. This study examines the effect of maternal high-fat diet on the expression of pancreatic glucose transporter 2 and the secretion of insulin in response to stress in offspring. Methods Female rats were randomly divided into normal and high-fat diet groups and were fed in a...

  18. Synchronized oviposition triggered by migratory flight intensifies larval outbreaks of beet webworm.

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    Yun Xia Cheng

    Full Text Available Identifying the reproductive consequences of insect migration is critical to understanding its ecological and evolutionary significance. However, many empirical studies are seemingly contradictory, making recognition of unifying themes elusive and controversial. The beet webworm, Loxostege sticticalis L. is a long-range migratory pest of many crops in the northern temperate zone from 36 °N to 55 °N, with larval populations often exploding in regions receiving immigrants. In laboratory experiments, we examined (i the reproductive costs of migratory flight by tethered flight, and (ii the reproductive traits contributing to larval outbreaks of immigrant populations. Our results suggest that the beet webworm does not initiate migratory flight until the 2nd or 3rd night after emergence. Preoviposition period, lifetime fecundity, mating capacity, and egg hatch rate for adults that experienced prolonged flight after the 2nd night did not differ significantly from unflown moths, suggesting these traits are irrelevant to the severity of beet webworm outbreaks after migration. However, the period of first oviposition, a novel parameter developed in this paper measuring synchrony of first egg-laying by cohorts of post-migratory females, for moths flown on d 3 and 5 of adulthood was shorter than that of unflown moths, indicating a tightened time-window for onset of oviposition after migration. The resulting synchrony of egg-laying will serve to increase egg and subsequent larval densities. A dense population offers potential selective advantages to the individual larvae comprising it, whereas the effect from the human standpoint is intensification of damage by an outbreak population. The strategy of synchronized oviposition may be common in other migratory insect pests, such as locust and armyworm species, and warrants further study.

  19. To What Extent Did the Financial Crisis Intensify the Pressure to Reform the Welfare State?

    DEFF Research Database (Denmark)

    Vis, Barbara; Kersbergen, Kees van; Hylands, Tom

    2011-01-01

    – it does not. Focusing on a selection of advanced welfare states (the UK, the USA, Germany, the Netherlands, Denmark and Sweden), we find that these countries face similar problems and that their initial response to these problems is also similar. The latter is surprising because, theoretically, we would...... expect varying responses across welfare state regime types. Rather than retrenchment, we observe a first phase of emergency capital injections in the banking sector and a second of Keynesian demand management and labour market protection, including the (temporary) expansion of social programmes...

  20. Utilizing TOPSIS intensified with adjustment similarity factor to determine price of technology

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    Seyed Mohammad Seyedhosseini

    2012-08-01

    Full Text Available Technology transfer has been a very frequent activity in the industrial world nowadays. Technology valuation, and in particular technology pricing, has played a considerable role in these transactions, in spite of a huge amount of limitations in the pricing methodologies applied. Making a sound, traceable and reliable means for applying the price evaluation procedure, seems as a technological requirement to be traced for. The objective of delivering this paper is to introduce a new numerical technology pricing method to provide the two transacting parties a unique compromised price. A three-dimensional model for technology pricing is proposed and The TOPSPS algorithm has been utilized to select the most similar technologies to the intended one and the constructed scoring system is applied to calculate the final technology price accordingly.