WorldWideScience

Sample records for singletons blastx searches

  1. Attentional control during visual search: The effect of irrelevant singletons

    NARCIS (Netherlands)

    Theeuwes, J.; Burger, R.

    1998-01-01

    Four experiments investigated whether a highly salient color singleton can be ignored during serial search. Observers searched for a target letter among nontarget letters and were instructed to ignore an irrelevant, highly salient color singleton that was either compatible or incompatible with the

  2. Singleton strings

    Energy Technology Data Exchange (ETDEWEB)

    Engquist, J. [Institute for Theoretical Physics and Spinoza Institute, Utrecht University (Netherlands); Sundell, P. [INFN, Pisa (Italy); Scuola Normale Superiore, Pisa (Italy); Tamassia, L. [Instituut voor Theoretische Fysica, Katholieke Universiteit Leuven, Celestijnenlaan 200D, 3001 Leuven (Belgium)

    2007-05-15

    The group theoretical structure underlying physics in anti de Sitter (AdS) spacetime is intrinsically different with respect to the flat case, due to the presence of special ultra-short representations, named singletons, that do not admit a flat space limit. The purpose of this collaboration is to exploit this feature in the study of string and brane dynamics in AdS spacetime, in particular while trying to establish a connection between String Theory in AdS backgrounds (in the tensionless limit) and Higher-Spin Gauge Theory. (orig.)

  3. Feature singletons attract spatial attention independently of feature priming.

    Science.gov (United States)

    Yashar, Amit; White, Alex L; Fang, Wanghaoming; Carrasco, Marisa

    2017-08-01

    People perform better in visual search when the target feature repeats across trials (intertrial feature priming [IFP]). Here, we investigated whether repetition of a feature singleton's color modulates stimulus-driven shifts of spatial attention by presenting a probe stimulus immediately after each singleton display. The task alternated every two trials between a probe discrimination task and a singleton search task. We measured both stimulus-driven spatial attention (via the distance between the probe and singleton) and IFP (via repetition of the singleton's color). Color repetition facilitated search performance (IFP effect) when the set size was small. When the probe appeared at the singleton's location, performance was better than at the opposite location (stimulus-driven attention effect). The magnitude of this attention effect increased with the singleton's set size (which increases its saliency) but did not depend on whether the singleton's color repeated across trials, even when the previous singleton had been attended as a search target. Thus, our findings show that repetition of a salient singleton's color affects performance when the singleton is task relevant and voluntarily attended (as in search trials). However, color repetition does not affect performance when the singleton becomes irrelevant to the current task, even though the singleton does capture attention (as in probe trials). Therefore, color repetition per se does not make a singleton more salient for stimulus-driven attention. Rather, we suggest that IFP requires voluntary selection of color singletons in each consecutive trial.

  4. Role of Frontal Cortex in Attentional Capture by Singleton Distractors

    Science.gov (United States)

    de Fockert, Jan W.; Theeuwes, Jan

    2012-01-01

    The role of frontal cortex in selective attention to visual distractors was examined in an attentional capture task in which participants searched for a unique shape in the presence or absence of an additional colour singleton distractor. The presence of the additional singleton was associated with slower behavioural responses to the shape target,…

  5. The allocation of attention in displays with simultaneously presented singletons

    NARCIS (Netherlands)

    Akyürek, Elkan G; Schubö, Anna

    In an ERP experiment, we investigated whether a 'permanent salient distractor changes the deployment of attention to target and nontarget singletons. Observers searched for a color target in a search array that mainly consisted of black vertical lines, but also always contained a line in a

  6. Capture by colour: evidence for dimension-specific singleton capture.

    Science.gov (United States)

    Harris, Anthony M; Becker, Stefanie I; Remington, Roger W

    2015-10-01

    Previous work on attentional capture has shown the attentional system to be quite flexible in the stimulus properties it can be set to respond to. Several different attentional "modes" have been identified. Feature search mode allows attention to be set for specific features of a target (e.g., red). Singleton detection mode sets attention to respond to any discrepant item ("singleton") in the display. Relational search sets attention for the relative properties of the target in relation to the distractors (e.g., redder, larger). Recently, a new attentional mode was proposed that sets attention to respond to any singleton within a particular feature dimension (e.g., colour; Folk & Anderson, 2010). We tested this proposal against the predictions of previously established attentional modes. In a spatial cueing paradigm, participants searched for a colour target that was randomly either red or green. The nature of the attentional control setting was probed by presenting an irrelevant singleton cue prior to the target display and assessing whether it attracted attention. In all experiments, the cues were red, green, blue, or a white stimulus rapidly rotated (motion cue). The results of three experiments support the existence of a "colour singleton set," finding that all colour cues captured attention strongly, while motion cues captured attention only weakly or not at all. Notably, we also found that capture by motion cues in search for colour targets was moderated by their frequency; rare motion cues captured attention (weakly), while frequent motion cues did not.

  7. PIR search result - KOME | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available e filtered with Expect values lower than 1e-10. Number of data entries 1,549,409 ...he searches. Data analysis method Performed blastx searches against the PIR protein database. The results ar

  8. UniProt search blastx result: AK287891 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287891 J065209I11 P47865|AQP1_BOVIN Aquaporin-1 (AQP-1) (Aquaporin-CHIP) (Water c...hannel protein for red blood cells and kidney proximal tubule) (Water channel protein CHIP29) - Bos taurus (Bovine) 1.00E-19 ...

  9. GenBank blastx search result: AK242401 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK242401 J080068F24 AF179596.1 AF179596 Vibrio cholerae 569b mega-integron MInVc Vco27A, Vco27B, Vco28 (vco2...8), Vco29 (vco29), ORF23 genes, complete cds; insertion sequence IS1359 putative tr

  10. GenBank blastx search result: AK058456 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK058456 001-015-H08 AF466202.2 Zea mays putative pol protein gene, partial cds; and puta...tive gag-pol precursor -orf2, putative Fourf gag/pol protein, putative NADP-dependent malic enzyme, puta...tive argonaute protein, putative pinhead protein, putative pol protein, putative gag protein, putative TNP2, r1-B73 proteins, puta...tive genetic modifier, putative S-receptor kinase, putati...ve aldose reductase-related protein, putative glutathione peroxidase, putative glycerol 3-phosphate permease, puta

  11. GenBank blastx search result: AK063143 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK063143 001-111-G11 AF466202.2 Zea mays putative pol protein gene, partial cds; and puta...tive gag-pol precursor -orf2, putative Fourf gag/pol protein, putative NADP-dependent malic enzyme, puta...tive argonaute protein, putative pinhead protein, putative pol protein, putative gag protein, putative TNP2, r1-B73 proteins, puta...tive genetic modifier, putative S-receptor kinase, putati...ve aldose reductase-related protein, putative glutathione peroxidase, putative glycerol 3-phosphate permease, puta

  12. GenBank blastx search result: AK288695 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288695 J090060N21 AF466202.2 AF466202 Zea mays putative pol protein gene, partial cds; and puta...tive gag-pol precursor -orf2, putative Fourf gag/pol protein, putative NADP-dependent malic enzyme, puta...tive argonaute protein, putative pinhead protein, putative pol protein, putative gag protein, puta...tive TNP2, r1-B73 proteins, putative genetic modifier, putative S-receptor kinase, puta...tive aldose reductase-related protein, putative glutathione peroxidase, putative glycerol 3-phosphate permease, puta

  13. GenBank blastx search result: AK241103 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK241103 J065079A13 AF466202.2 AF466202 Zea mays putative pol protein gene, partial cds; and puta...tive gag-pol precursor -orf2, putative Fourf gag/pol protein, putative NADP-dependent malic enzyme, puta...tive argonaute protein, putative pinhead protein, putative pol protein, putative gag protein, puta...tive TNP2, r1-B73 proteins, putative genetic modifier, putative S-receptor kinase, puta...tive aldose reductase-related protein, putative glutathione peroxidase, putative glycerol 3-phosphate permease, puta

  14. GenBank blastx search result: AK289066 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK289066 J090094A21 AF466202.2 AF466202 Zea mays putative pol protein gene, partial cds; and puta...tive gag-pol precursor -orf2, putative Fourf gag/pol protein, putative NADP-dependent malic enzyme, puta...tive argonaute protein, putative pinhead protein, putative pol protein, putative gag protein, puta...tive TNP2, r1-B73 proteins, putative genetic modifier, putative S-receptor kinase, puta...tive aldose reductase-related protein, putative glutathione peroxidase, putative glycerol 3-phosphate permease, puta

  15. GenBank blastx search result: AK104301 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK104301 001-011-A08 AF466202.2 Zea mays putative pol protein gene, partial cds; and puta...tive gag-pol precursor -orf2, putative Fourf gag/pol protein, putative NADP-dependent malic enzyme, puta...tive argonaute protein, putative pinhead protein, putative pol protein, putative gag protein, putative TNP2, r1-B73 proteins, puta...tive genetic modifier, putative S-receptor kinase, putati...ve aldose reductase-related protein, putative glutathione peroxidase, putative glycerol 3-phosphate permease, puta

  16. GenBank blastx search result: AK112025 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK112025 001-036-C05 AF466202.2 Zea mays putative pol protein gene, partial cds; and puta...tive gag-pol precursor -orf2, putative Fourf gag/pol protein, putative NADP-dependent malic enzyme, puta...tive argonaute protein, putative pinhead protein, putative pol protein, putative gag protein, putative TNP2, r1-B73 proteins, puta...tive genetic modifier, putative S-receptor kinase, putati...ve aldose reductase-related protein, putative glutathione peroxidase, putative glycerol 3-phosphate permease, puta

  17. UniProt search blastx result: AK289104 [KOME

    Lifescience Database Archive (English)

    Full Text Available ensing ion channel 3) (ASIC3) (hASIC3) (Testis sodium channel 1) (hTNaC1) - Homo sapiens (Human) 0 ... ...AK289104 J090096G16 Q9UHC3|ACCN3_HUMAN Amiloride-sensitive cation channel 3 (Acid-s

  18. GenBank blastx search result: AK058791 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK058791 001-002-F06 J05111.1 Anabaena PCC7120 nitrogenase (nifB), ferrodoxin-like ...protein (fdxN), nifS (nifS), nifU (nifU), and nitrogenase reductase (nifH) genes, complete cds.|BCT BCT 9e-14 +3 ...

  19. GenBank blastx search result: AK103983 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK103983 001-017-F09 J05111.1 Anabaena PCC7120 nitrogenase (nifB), ferrodoxin-like ...protein (fdxN), nifS (nifS), nifU (nifU), and nitrogenase reductase (nifH) genes, complete cds.|BCT BCT 1e-14 +2 ...

  20. GenBank blastx search result: AK243477 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK243477 J100072I17 AF009672.1 AF009672 Acinetobacter sp. ADP1 VanR (vanR), vanilla...te demethylase (vanB), vanillate demethylase (vanA), and VanK (vanK) genes, complete cds; and unknown genes. BCT 1e-19 1 ...

  1. UniProt search blastx result: AK288448 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288448 J090034N14 P48545|IRK5_MOUSE G protein-activated inward rectifier potassiu...m channel 4 (GIRK4) (Potassium channel, inwardly rectifying subfamily J member 5) (Inward rectifier K(+) cha...nnel Kir3.4) (Heart KATP channel) (KATP-1) (Cardiac inward rectifier) (CIR) - Mus musculus (Mouse) 0 ...

  2. UniProt search blastx result: AK287609 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287609 J065058I05 O88676|MMP23_MOUSE Matrix metalloproteinase-23 precursor (EC 3....4.24.-) (MMP-23) (CAMP metalloproteinase) (CA-MMP) [Contains: Matrix metalloproteinase-23, soluble form] - Mus musculus (Mouse) 1.00E-20 ...

  3. GenBank blastx search result: AK287747 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287747 J065152G10 BT002882.1 BT002882 Arabidopsis thaliana clone RAFL14-83-B05 (R20416) putative pinoresin...ol-lariciresinol reductase (At4g13660) mRNA, complete cds. PLN 9e-98 0 ...

  4. GenBank blastx search result: AK061785 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK061785 001-039-E07 AB121971.1 Thermosynechococcus vulcanus kaiA, kaiB, kaiC genes for circadian clock... protein KaiA, circadian clock protein KaiB, circadian clock protein KaiC, complete and partial cds.|BCT BCT 4e-20 +2 ...

  5. GenBank blastx search result: AK289181 [KOME

    Lifescience Database Archive (English)

    Full Text Available iC genes for circadian clock protein KaiA, circadian clock protein KaiB, circadian clock protein KaiC, complete and partial cds. BCT 2e-19 0 ... ...AK289181 J100029B03 AB121971.1 AB121971 Thermosynechococcus vulcanus kaiA, kaiB, ka

  6. GenBank blastx search result: AK060751 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK060751 001-032-G04 AB121971.1 Thermosynechococcus vulcanus kaiA, kaiB, kaiC genes for circadian clock... protein KaiA, circadian clock protein KaiB, circadian clock protein KaiC, complete and partial cds.|BCT BCT 9e-26 +1 ...

  7. GenBank blastx search result: AK243031 [KOME

    Lifescience Database Archive (English)

    Full Text Available iC genes for circadian clock protein KaiA, circadian clock protein KaiB, circadian clock protein KaiC, complete and partial cds. BCT 1e-19 1 ... ...AK243031 J100004F15 AB121971.1 AB121971 Thermosynechococcus vulcanus kaiA, kaiB, ka

  8. GenBank blastx search result: AK243490 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK243490 J100073N23 M90094.1 PHRRIBABH Photobacterium leiognathi riboflavin synthet...ase alpha subunit (ribB), riboflavin synthetase beta subunit (ribH), complete cds's. BCT 4e-26 1 ...

  9. GenBank blastx search result: AK058464 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK058464 001-016-A10 U27202.1 Actinobacillus pleuropneumoniae riboflavin biosynthesis operon, riboflavin...-specific deaminase (ribG), riboflavin synthase alpha subunit (ribB), bifunctional GTP ...cyclohydrase II/3,4-dihydroxy-2-butanone-4-phosphate synthase (ribA), and riboflavin synthase beta subunit (ribH) genes, complete cds.|BCT BCT 1e-105 +2 ...

  10. GenBank blastx search result: AK241452 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK241452 J065163N15 M90094.1 PHRRIBABH Photobacterium leiognathi riboflavin synthet...ase alpha subunit (ribB), riboflavin synthetase beta subunit (ribH), complete cds's. BCT 2e-71 1 ...

  11. GenBank blastx search result: AK058464 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK058464 001-016-A10 M90094.1 Photobacterium leiognathi riboflavin synthetase alpha subunit (ribB), riboflav...in synthetase beta subunit (ribH), complete cds's.|BCT BCT 4e-69 +2 ...

  12. GenBank blastx search result: AK243269 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK243269 J100049H19 L41732.4 ABCLSDA Gluconacetobacter diazotrophicus levansucrase precursor (lsd...A), levanase precursor (lsdB), pseudopilin G precursor (lsdG), prepilin peptidase and N-methyl...transferase O (gspO), kinase E (lsdE), LsdF (lsdF), pseudopilin H precursor (lsdH), pseudopilin I precursor (lsd...I), pseudopilin J precursor (lsdJ), LsdL (lsdL), LsdM (lsdM), and LsdN (lsdN)... genes, complete cds; secretin D (lsdD) gene, partial cds; and unknown gene. BCT 6e-26 1 ...

  13. GenBank blastx search result: AK289049 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK289049 J090092N07 BC022513.1 BC022513 Homo sapiens coagulation factor VIII, procoagulant component (hemoph...ilia A), mRNA (cDNA clone IMAGE:4815208), complete cds. PRI 0.0 0 ...

  14. GenBank blastx search result: AK289049 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK289049 J090092N07 BC064380.1 BC064380 Homo sapiens coagulation factor VIII, procoagulant component (hemoph...ilia A), mRNA (cDNA clone IMAGE:5733897), complete cds. PRI 0.0 0 ...

  15. GenBank blastx search result: AK289049 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK289049 J090092N07 BC111969.1 BC111969 Homo sapiens coagulation factor VIII, procoagulant component (hemoph...ilia A), transcript variant 2, mRNA (cDNA clone IMAGE:8327437), complete cds. PRI 0.0 0 ...

  16. GenBank blastx search result: AK289049 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK289049 J090092N07 BC098389.1 BC098389 Homo sapiens coagulation factor VIII, procoagulant component (hemoph...ilia A), mRNA (cDNA clone IMAGE:5284386), complete cds. PRI 0.0 0 ...

  17. GenBank blastx search result: AK289049 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK289049 J090092N07 BC111967.1 BC111967 Homo sapiens coagulation factor VIII, procoagulant component (hemoph...ilia A), transcript variant 2, mRNA (cDNA clone IMAGE:8327435), complete cds. PRI 0.0 0 ...

  18. UniProt search blastx result: AK287696 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287696 J065129N03 P36366|FMO2_CAVPO Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulm...onary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) - Cavia porcellus (Guinea pig) 4.00E-15 ...

  19. UniProt search blastx result: AK287696 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287696 J065129N03 Q8HZ69|FMO2_GORGO Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulm...onary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) - Gorilla gorilla gorilla (Lowland gorilla) 3.00E-14 ...

  20. UniProt search blastx result: AK287696 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287696 J065129N03 P17635|FMO2_RABIT Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulm...onary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) - Oryctolagus cuniculus (Rabbit) 1.00E-16 ...

  1. UniProt search blastx result: AK287696 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287696 J065129N03 Q5REK0|FMO2_PONPY Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulm...onary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) - Pongo pygmaeus (Orangutan) 8.00E-14 ...

  2. UniProt search blastx result: AK287696 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287696 J065129N03 Q6IRI9|FMO2_RAT Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmon...ary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) - Rattus norvegicus (Rat) 6.00E-17 ...

  3. UniProt search blastx result: AK287578 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287578 J065038J02 Q8K2I3|FMO2_MOUSE Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulm...onary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) - Mus musculus (Mouse) 2.00E-15 ...

  4. UniProt search blastx result: AK287696 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287696 J065129N03 Q8K2I3|FMO2_MOUSE Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulm...onary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) - Mus musculus (Mouse) 2.00E-14 ...

  5. UniProt search blastx result: AK287578 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287578 J065038J02 P17635|FMO2_RABIT Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulm...onary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) - Oryctolagus cuniculus (Rabbit) 2.00E-17 ...

  6. UniProt search blastx result: AK287578 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287578 J065038J02 Q99518|FMO2_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulm...onary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) - Homo sapiens (Human) 4.00E-15 ...

  7. UniProt search blastx result: AK287578 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287578 J065038J02 Q8HZ70|FMO2_PANTR Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulm...onary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) - Pan troglodytes (Chimpanzee) 6.00E-15 ...

  8. UniProt search blastx result: AK287696 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287696 J065129N03 Q8HZ70|FMO2_PANTR Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulm...onary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) - Pan troglodytes (Chimpanzee) 4.00E-14 ...

  9. UniProt search blastx result: AK287578 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287578 J065038J02 Q6IRI9|FMO2_RAT Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulmon...ary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) - Rattus norvegicus (Rat) 7.00E-18 ...

  10. UniProt search blastx result: AK287578 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287578 J065038J02 P36366|FMO2_CAVPO Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulm...onary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) - Cavia porcellus (Guinea pig) 5.00E-16 ...

  11. UniProt search blastx result: AK287578 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287578 J065038J02 Q8HZ69|FMO2_GORGO Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulm...onary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) - Gorilla gorilla gorilla (Lowland gorilla) 4.00E-15 ...

  12. UniProt search blastx result: AK287578 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287578 J065038J02 Q28505|FMO2_MACMU Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulm...onary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) - Macaca mulatta (Rhesus macaque) 1.00E-14 ...

  13. UniProt search blastx result: AK287578 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287578 J065038J02 Q5REK0|FMO2_PONPY Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulm...onary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) - Pongo pygmaeus (Orangutan) 1.00E-14 ...

  14. UniProt search blastx result: AK287696 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287696 J065129N03 Q99518|FMO2_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulm...onary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) - Homo sapiens (Human) 3.00E-14 ...

  15. UniProt search blastx result: AK287696 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287696 J065129N03 Q28505|FMO2_MACMU Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8) (Pulm...onary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) - Macaca mulatta (Rhesus macaque) 1.00E-13 ...

  16. GenBank blastx search result: AK288647 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288647 J090056K16 BC096137.1 BC096137 Homo sapiens transition protein 2 (during histone to protamine repla...cement), mRNA (cDNA clone MGC:116785 IMAGE:40002553), complete cds. PRI 0.0 0 ...

  17. GenBank blastx search result: AK288647 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288647 J090056K16 BC096135.3 BC096135 Homo sapiens transition protein 2 (during histone to protamine repla...cement), mRNA (cDNA clone MGC:116782 IMAGE:40002547), complete cds. PRI 0.0 0 ...

  18. GenBank blastx search result: AK288647 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288647 J090056K16 BC096136.3 BC096136 Homo sapiens transition protein 2 (during histone to protamine repla...cement), mRNA (cDNA clone MGC:116783 IMAGE:40002550), complete cds. PRI 0.0 0 ...

  19. GenBank blastx search result: AK059350 [KOME

    Lifescience Database Archive (English)

    Full Text Available r SLU7; DNA segment, Chr 11, ERATO Doi 730, expressed; DNA segment, Chr 3, Brigham & Womens Genetics 0878 expressed, mRNA (cDNA clone IMAGE:6890616), partial cds.|ROD ROD 1e-103 +3 ...

  20. UniProt search blastx result: AK287903 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287903 J065211G19 O08529|CAN2_MOUSE Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain...-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (M-calpain) (Millimolar-calpain...) (80 kDa M-calpain subunit) (CALP80) - Mus musculus (Mouse) 0 ...

  1. UniProt search blastx result: AK287903 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287903 J065211G19 Q9GLG1|CAN2_MACFA Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain...-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (M-calpain) (Millimolar-calpain

  2. UniProt search blastx result: AK287903 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287903 J065211G19 Q92178|CAN2_CHICK Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain...-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (M-calpain) (Millimolar-calpain) - Gallus gallus (Chicken) 0 ...

  3. UniProt search blastx result: AK287903 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287903 J065211G19 Q07009|CAN2_RAT Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain...-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (M-calpain) (Millimolar-calpain) - Rattus norvegicus (Rat) 0 ...

  4. UniProt search blastx result: AK287903 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287903 J065211G19 P43367|CAN2_PIG Calpain-2 catalytic subunit (EC 3.4.22.53) (Calpain...-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (M-calpain) (Millimolar-calpain) (Fragment) - Sus scrofa (Pig) 0 ...

  5. UniProt search blastx result: AK287903 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287903 J065211G19 P17655|CAN2_HUMAN Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain...-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (M-calpain) (Millimolar-calpain...) (Calpain large polypeptide L2) - Homo sapiens (Human) 0 ...

  6. UniProt search blastx result: AK287903 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287903 J065211G19 P06814|CAN2_RABIT Calpain-2 catalytic subunit (EC 3.4.22.53) (Calpain...-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (M-calpain) (Millimolar-calpain) (Fragment) - Oryctolagus cuniculus (Rabbit) 0 ...

  7. UniProt search blastx result: AK287891 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287891 J065209I11 Q6Z2T3|NIP21_ORYSJ Aquaporin NIP2-1 (NOD26-like intrinsic protein 2-1) (OsNIP2;1) (Silic...on transporter LSI1) (Low silicon protein 1) - Oryza sativa subsp. japonica (Rice) 4.00E-14 ...

  8. UniProt search blastx result: AK287474 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287474 J043022N04 P04917|PGSG_RAT Secretory granule proteoglycan core protein pre...cursor (Chondroitin sulfate proteoglycan core protein) (Proteoglycan 10K core protein) (PG19 core protein) (Cytolytic granule proteoglycan core protein) - Rattus norvegicus (Rat) 0 ...

  9. GenBank blastx search result: AK242273 [KOME

    Lifescience Database Archive (English)

    Full Text Available novel pseudogene, the Havcr2 gene for hepatitis A virus cellular receptor 2, the gene for a novel protein similar to hepatitis... A virus cellular receptor 1 Havcr1, two hepatitis A virus cel...lular receptor (Havcr) pseudogenes, wo novel genes, a ribosomal protein L9 (Rpl9) pseudogene, the gene for a novel hepatitis

  10. GenBank blastx search result: AK104735 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK104735 001-038-D01 BT002882.1 Arabidopsis thaliana clone RAFL14-83-B05 (R20416) putative pinoresin...ol-lariciresinol reductase (At4g13660) mRNA, complete cds.|PLN PLN 4e-55 +1 ...

  11. UniProt search blastx result: AK287662 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287662 J065112L10 Q28433|TAP1_GORGO Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP-binding cassette sub-family B member 2) - Gorilla gorilla gorilla (Lowland gorilla) 2.00E-95 ...

  12. GenBank blastx search result: AK288081 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288081 J075172F18 U09568.1 MGU09568 Lymphoproliferative disease virus of Meleagris gallopavo Gag precurso...r, protease p16, Pol precursor, Env precursor, ORF1 and ORF3 genes, complete cds. VRL 0.0 0 ...

  13. GenBank blastx search result: AK060683 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK060683 001-029-F09 U43202.1 RFP provirus of Murine leukemia virus gag precursor protein, pol precurso...r protein, env precursor protein genes, complete cds.|VRL VRL 1e-12 +2 ...

  14. GenBank blastx search result: AK287639 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287639 J065078H11 AF287967.1 AF287967 Homo sapiens homeobox B7 (HOXB7) gene, partial cds; and home...obox B6 (HOXB6), homeobox B5 (HOXB5), homeobox B4 (HOXB4), and homeobox B3 (HOXB3) genes, complete cds. PRI 0.0 0 ...

  15. GenBank blastx search result: AK108618 [KOME

    Lifescience Database Archive (English)

    Full Text Available al cds; putative Cf-2, fertilization-independent endosperm proteins, hypothetical protein, putative non-LTR ...AK108618 002-147-C04 AF466200.2 Sorghum bicolor putative protein kinase gene, parti

  16. GenBank blastx search result: AK059048 [KOME

    Lifescience Database Archive (English)

    Full Text Available al cds; putative Cf-2, fertilization-independent endosperm proteins, hypothetical protein, putative non-LTR ...AK059048 001-021-D12 AF466200.2 Sorghum bicolor putative protein kinase gene, parti

  17. GenBank blastx search result: AK104825 [KOME

    Lifescience Database Archive (English)

    Full Text Available al cds; putative Cf-2, fertilization-independent endosperm proteins, hypothetical protein, putative non-LTR ...AK104825 001-041-F09 AF466200.2 Sorghum bicolor putative protein kinase gene, parti

  18. GenBank blastx search result: AK119477 [KOME

    Lifescience Database Archive (English)

    Full Text Available al cds; putative Cf-2, fertilization-independent endosperm proteins, hypothetical protein, putative non-LTR ...AK119477 001-134-B09 AF466200.2 Sorghum bicolor putative protein kinase gene, parti

  19. GenBank blastx search result: AK119355 [KOME

    Lifescience Database Archive (English)

    Full Text Available al cds; putative Cf-2, fertilization-independent endosperm proteins, hypothetical protein, putative non-LTR ...AK119355 001-131-F11 AF466200.2 Sorghum bicolor putative protein kinase gene, parti

  20. GenBank blastx search result: AK064276 [KOME

    Lifescience Database Archive (English)

    Full Text Available al cds; putative Cf-2, fertilization-independent endosperm proteins, hypothetical protein, putative non-LTR ...AK064276 002-105-F03 AF466200.2 Sorghum bicolor putative protein kinase gene, parti

  1. GenBank blastx search result: AK059033 [KOME

    Lifescience Database Archive (English)

    Full Text Available al cds; putative Cf-2, fertilization-independent endosperm proteins, hypothetical protein, putative non-LTR ...AK059033 001-021-C06 AF466200.2 Sorghum bicolor putative protein kinase gene, parti

  2. GenBank blastx search result: AK059987 [KOME

    Lifescience Database Archive (English)

    Full Text Available al cds; putative Cf-2, fertilization-independent endosperm proteins, hypothetical protein, putative non-LTR ...AK059987 006-212-H01 AF466200.2 Sorghum bicolor putative protein kinase gene, parti

  3. GenBank blastx search result: AK060772 [KOME

    Lifescience Database Archive (English)

    Full Text Available al cds; putative Cf-2, fertilization-independent endosperm proteins, hypothetical protein, putative non-LTR ...AK060772 001-033-B05 AF466200.2 Sorghum bicolor putative protein kinase gene, parti

  4. UniProt search blastx result: AK287438 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287438 J043014M18 P52948|NUP98_HUMAN Nuclear pore complex protein Nup98-Nup96 pre...cursor [Contains: Nuclear pore complex protein Nup98 (Nucleoporin Nup98) (98 kDa nucleoporin); Nuclear pore

  5. GenBank blastx search result: AK104832 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK104832 001-042-A09 L25604.2 Bacillus subtilis bmrU (bmrU) and multidrug-efflux transporter (bmr...) genes, complete cds; bmrR gene, complete sequence; multidrug-efflux transporter regulator (bmr

  6. GenBank blastx search result: AK119179 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK119179 001-037-G09 AF489516.1 Methylobacterium extorquens tungsten-containing for...mate dehydrogenase beta subunit and tungsten-containing formate dehydrogenase alpha subunit genes, complete cds.|BCT BCT 3e-49 +3 ...

  7. UniProt search blastx result: AK289096 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK289096 J090096D02 Q29432|PAG1_BOVIN Pregnancy-associated glycoprotein 1 precursor... (EC 3.4.23.-) (PAG 1) (Pregnancy-specific protein B) (PSP-B) - Bos taurus (Bovine) 9.00E-45 ...

  8. GenBank blastx search result: AK103983 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK103983 001-017-F09 U49859.1 Anabaena variabilis Mo-nitrogenase operon NifB2, NifS2, NifU2, dinitrogen...ase reductase (nifH2), dinitrogenase alpha subunit (nifD2), dinitrogenase beta subunit (

  9. GenBank blastx search result: AK058791 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK058791 001-002-F06 U49859.1 Anabaena variabilis Mo-nitrogenase operon NifB2, NifS2, NifU2, dinitrogen...ase reductase (nifH2), dinitrogenase alpha subunit (nifD2), dinitrogenase beta subunit (

  10. GenBank blastx search result: AK060074 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK060074 006-306-B05 U49859.1 Anabaena variabilis Mo-nitrogenase operon NifB2, NifS2, NifU2, dinitrogen...ase reductase (nifH2), dinitrogenase alpha subunit (nifD2), dinitrogenase beta subunit (

  11. GenBank blastx search result: AK059171 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK059171 001-023-F01 U49859.1 Anabaena variabilis Mo-nitrogenase operon NifB2, NifS2, NifU2, dinitrogen...ase reductase (nifH2), dinitrogenase alpha subunit (nifD2), dinitrogenase beta subunit (

  12. GenBank blastx search result: AK062234 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK062234 001-047-D11 U49859.1 Anabaena variabilis Mo-nitrogenase operon NifB2, NifS2, NifU2, dinitrogen...ase reductase (nifH2), dinitrogenase alpha subunit (nifD2), dinitrogenase beta subunit (

  13. GenBank blastx search result: AK287588 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287588 J065045K19 L20792.1 MOTSERPINB Manduca sexta (clones H5, H10, H14, H17) pu...tative serine proteinase inhibitor (serpin 1, exon 9 copy 2) mRNA, complete cds. INV 1e-19 0 ...

  14. GenBank blastx search result: AK287588 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287588 J065045K19 BT025406.1 BT025406 Bos taurus serpin peptidase inhibitor, clad...e E (nexin, plasminogen activator inhibitor type 1), member 1 (SERPINE1), mRNA, complete cds. MAM 9e-21 0 ...

  15. GenBank blastx search result: AK243629 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK243629 J100087B22 L20792.1 MOTSERPINB Manduca sexta (clones H5, H10, H14, H17) pu...tative serine proteinase inhibitor (serpin 1, exon 9 copy 2) mRNA, complete cds. INV 6e-29 1 ...

  16. UniProt search blastx result: AK288448 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288448 J090034N14 P48548|IRK5_RAT G protein-activated inward rectifier potassium ...channel 4 (GIRK4) (Potassium channel, inwardly rectifying subfamily J member 5) (Inward rectifier K(+) chann...el Kir3.4) (Heart KATP channel) (KATP-1) (Cardiac inward rectifier) (CIR) - Rattus norvegicus (Rat) 0 ...

  17. GenBank blastx search result: AK104297 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK104297 001-008-H10 AY259120.1 Pseudomonas sp. Hsa.28 COG 3384-like protein gene, partial cds; thiopurine methyltransferase (tpm) gene, tpm-I allele, complete cds; and HtpX gene, partial cds.|BCT BCT 4e-27 +3 ...

  18. GenBank blastx search result: AK104780 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK104780 001-039-C06 AY026914.1 Pseudomonas putida strain P111 czrBA operon, partial sequence; ben operon... and ant operon, complete sequence; and catRBCA operon, partial sequence; and unknown gene.|BCT BCT 3e-11 +2 ...

  19. GenBank blastx search result: AK287557 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287557 J065021C17 AY026914.1 AY026914 Pseudomonas putida strain P111 czrBA operon..., partial sequence; ben operon and ant operon, complete sequence; and catRBCA operon, partial sequence; and unknown gene. BCT 0.0 0 ...

  20. GenBank blastx search result: AK109330 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK109330 006-201-C10 AY026914.1 Pseudomonas putida strain P111 czrBA operon, partial sequence; ben operon... and ant operon, complete sequence; and catRBCA operon, partial sequence; and unknown gene.|BCT BCT 3e-11 +2 ...

  1. GenBank blastx search result: AK289020 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK289020 J090090F09 AY026914.1 AY026914 Pseudomonas putida strain P111 czrBA operon..., partial sequence; ben operon and ant operon, complete sequence; and catRBCA operon, partial sequence; and unknown gene. BCT 0.0 0 ...

  2. UniProt search blastx result: AK287848 [KOME

    Lifescience Database Archive (English)

    Full Text Available uitinating enzyme FAF-X) (Fat facets protein-related, X-linked) (Ubiquitin-specific protease 9, X chromosome...) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog) - Mus musculus (Mouse) 4.00E-16 ...

  3. GenBank blastx search result: AK289008 [KOME

    Lifescience Database Archive (English)

    Full Text Available omycin resistance operon, complete sequence, and ORFG2-24, ORFG2-26, and ORFG2-27 genes, complete cds; and OrfG2-25 gene, complete cds. BCT 0.0 0 ... ...AK289008 J090089C06 DQ222944.1 DQ222944 Enterococcus faecalis VanG2 element ORFG2-22 gene, partial cds, vanc

  4. GenBank blastx search result: AK243321 [KOME

    Lifescience Database Archive (English)

    Full Text Available hine carbamoyl transferase (argF) gene, partial cds; xasA gene, complete sequence; LabD (labD) and putative ...carbamate kinase-like carbamyl phosphate synthase (cpkA) genes, complete cds; and LabE (labE) gene, partial cds. BCT 1e-104 1 ...

  5. GenBank blastx search result: AK243192 [KOME

    Lifescience Database Archive (English)

    Full Text Available hine carbamoyl transferase (argF) gene, partial cds; xasA gene, complete sequence; LabD (labD) and putative ...carbamate kinase-like carbamyl phosphate synthase (cpkA) genes, complete cds; and LabE (labE) gene, partial cds. BCT 4e-20 1 ...

  6. GenBank blastx search result: AK060423 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK060423 001-010-H01 AY498612.1 Rhodococcus opacus putative GntR type regulator of taurine... degradation (tauR) gene, partial cds; and alanine dehydrogenase (ald) and taurine-pyruvate aminotransferase (tpa) genes, complete cds.|BCT BCT 7e-32 +3 ...

  7. GenBank blastx search result: AK104002 [KOME

    Lifescience Database Archive (English)

    Full Text Available opy of the insertion element IS2 is inserted after cloning in E.coli by duplicating a 5 base pair sequence. This is the wildtype TRP5 gene before insertion of IS2.|PLN PLN 6e-22 +1 ...

  8. GenBank blastx search result: AK105071 [KOME

    Lifescience Database Archive (English)

    Full Text Available elta, alpha, and gamma respectively) and gene1 for unknown product.|BCT BCT 1e-77 +3 ... ...he FoF1 ATP synthase: genes atpI, atpH, atpG, atpF, atpD, atpA, and atpC (for ATPase subunits a, c, b', b, d

  9. GenBank blastx search result: AK287567 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287567 J065028B09 AF335329.1 AF335329 Kallichroma tethys isopenicillin N synthase (pcb...C) and alpha-aminoadipyl-cysteinyl-valine synthetase (pcbAB) genes, complete cds. PLN 0.0 0 ...

  10. GenBank blastx search result: AK243477 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK243477 J100072I17 AF335329.1 AF335329 Kallichroma tethys isopenicillin N synthase (pcb...C) and alpha-aminoadipyl-cysteinyl-valine synthetase (pcbAB) genes, complete cds. PLN 5e-18 1 ...

  11. GenBank blastx search result: AK104871 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK104871 001-044-B11 AF335329.1 Kallichroma tethys isopenicillin N synthase (pcbC) ...and alpha-aminoadipyl-cysteinyl-valine synthetase (pcbAB) genes, complete cds.|PLN PLN 6e-15 +3 ...

  12. GenBank blastx search result: AK242797 [KOME

    Lifescience Database Archive (English)

    Full Text Available sinase protein phosphatase genes, complete cds. BCT 2e-23 1 ... ..., RpsO, metallo beta subunit lactamase, hypothetical protein, Tuf, trigger factor, Clp protease, GTP binding protein, and phosphotyro

  13. GenBank blastx search result: AK243408 [KOME

    Lifescience Database Archive (English)

    Full Text Available sinase protein phosphatase genes, complete cds. BCT 1e-101 1 ... ..., RpsO, metallo beta subunit lactamase, hypothetical protein, Tuf, trigger factor, Clp protease, GTP binding protein, and phosphotyro

  14. GenBank blastx search result: AK062096 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK062096 001-044-H12 M91440.1 Pseudomonas sp. alcohol dehydrogenase (terpD) gene, c...omplete cds; aldehyde dehydrogenase (terpE) gene, complete cds; P450terp (terpC) gene, complete cds; terpredoxin reductase (terp...A) gene, complete cds; terpredoxin (terpB) gene, complete cds.|BCT BCT 1e-11 +3 ...

  15. UniProt search blastx result: AK289192 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK289192 J100039P10 Q06602|APD73_APIME Apidaecins type 73 precursor [Contains: Apidaecin; Apidaecin-1B (Apid...aecin IB); Apidaecin-1A (Apidaecin IA)] (Fragment) - Apis mellifera (Honeybee) 0 ...

  16. UniProt search blastx result: AK289192 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK289192 J100039P10 Q06601|APD14_APIME Apidaecins type 14 precursor [Contains: Apidaecin-2 (Apidae...cin II); Apidaecin-1B (Apidaecin IB); Apidaecin-1A (Apidaecin IA)] - Apis mellifera (Honeybee) 0 ...

  17. GenBank blastx search result: AK104368 [KOME

    Lifescience Database Archive (English)

    Full Text Available l cds; and putative urea transporter, urease accessory protein D, urease accessory protein G, urease accesso...ry protein F, and urease accessory protein E genes, complete cds.|BCT BCT 2e-47 +1 ...

  18. GenBank blastx search result: AK243063 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK243063 J100015C16 BC049743.1 BC049743 Mus musculus Machado-Joseph disease (spinocerebellar ataxia... 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3) homolog (human), mRNA (cDNA clone IMAGE:6772218), partial cds. ROD 6e-33 1 ...

  19. GenBank blastx search result: AK243063 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK243063 J100015C16 BC087880.1 BC087880 Mus musculus Machado-Joseph disease (spinocerebellar ataxia... 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3) homolog (human), mRNA (cDNA clone MGC:107148 IMAGE:6771498), complete cds. ROD 6e-33 1 ...

  20. GenBank blastx search result: AK288311 [KOME

    Lifescience Database Archive (English)

    Full Text Available (UL26), virion scaffolding protein (UL26.5), virion membrane glycoprotein B (gB), DNA cleavage/packaging pro... subunit (pol), nuclear phosphoprotein (UL31), DNA cleavage/packaging (UL32), DNA cleavage/packaging protein

  1. UniProt search blastx result: AK287609 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287609 J065058I05 P03956|MMP1_HUMAN Interstitial collagenase precursor (EC 3.4.24....7) (Matrix metalloproteinase-1) (MMP-1) (Fibroblast collagenase) [Contains: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase] - Homo sapiens (Human) 2.00E-31 ...

  2. GenBank blastx search result: AK059429 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK059429 001-027-F01 S81752.1 DPH2L=candidate tumor suppressor gene {ovarian cancer critical region of delet...ion} [human, 9 week fetal and placental tissues, mRNA, 2233 nt].|PRI PRI 2e-64 +2 ...

  3. UniProt search blastx result: AK288998 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288998 J090088E15 P30996|BXF_CLOBO Botulinum neurotoxin type F precursor (EC 3.4....24.69) (BoNT/F) (Bontoxilysin-F) [Contains: Botulinum neurotoxin F light chain; Botulinum neurotoxin F heavy chain] - Clostridium botulinum 0 ...

  4. GenBank blastx search result: AK110529 [KOME

    Lifescience Database Archive (English)

    Full Text Available ome 20 Contains the 3' end of the ZNF343 gene for zinc finger protein 343, the SNRPB gene for small nuclear ribonucleoprotein polypep...tides B and B1 (B'), the 3' end of the TGM6 gene for transglutaminase 6 and a CpG island, complete sequence.|PRI PRI 4e-22 +2 ...

  5. GenBank blastx search result: AK119219 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK119219 001-046-F11 AF046933.1 Thiobacillus intermedius K12 carboxysome polypeptides...enase small subunit (cbbS), and carboxysome structural polypeptides (csoS2, csoS3, csoS1C, csoS1A, csoS1B) genes, complete cds.|BCT BCT 5e-15 +3 ...

  6. GenBank blastx search result: AK288517 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288517 J090043B03 AF046933.1 AF046933 Thiobacillus intermedius K12 carboxysome polypeptides...ase/oxygenase small subunit (cbbS), and carboxysome structural polypeptides (csoS2, csoS3, csoS1C, csoS1A, csoS1B) genes, complete cds. BCT 6e-14 0 ...

  7. GenBank blastx search result: AK288054 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288054 J075152E14 AF046933.1 AF046933 Thiobacillus intermedius K12 carboxysome polypeptides...ase/oxygenase small subunit (cbbS), and carboxysome structural polypeptides (csoS2, csoS3, csoS1C, csoS1A, csoS1B) genes, complete cds. BCT 1e-14 0 ...

  8. GenBank blastx search result: AK061611 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK061611 001-032-F07 AF046933.1 Thiobacillus intermedius K12 carboxysome polypeptides...enase small subunit (cbbS), and carboxysome structural polypeptides (csoS2, csoS3, csoS1C, csoS1A, csoS1B) genes, complete cds.|BCT BCT 5e-15 +3 ...

  9. GenBank blastx search result: AK241131 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK241131 J065097J24 AF046933.1 AF046933 Thiobacillus intermedius K12 carboxysome polypeptides...ase/oxygenase small subunit (cbbS), and carboxysome structural polypeptides (csoS2, csoS3, csoS1C, csoS1A, csoS1B) genes, complete cds. BCT 2e-14 1 ...

  10. UniProt search blastx result: AK288287 [KOME

    Lifescience Database Archive (English)

    Full Text Available C 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) - Neofelis nebulosa (Clouded leopard) 3.00E-18 ...

  11. UniProt search blastx result: AK289170 [KOME

    Lifescience Database Archive (English)

    Full Text Available C 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) - Neofelis nebulosa (Clouded leopard) 1.00E-18 ...

  12. UniProt search blastx result: AK287484 [KOME

    Lifescience Database Archive (English)

    Full Text Available C 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) - Neofelis nebulosa (Clouded leopard) 3.00E-16 ...

  13. UniProt search blastx result: AK288291 [KOME

    Lifescience Database Archive (English)

    Full Text Available C 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) - Neofelis nebulosa (Clouded leopard) 6.00E-14 ...

  14. UniProt search blastx result: AK288206 [KOME

    Lifescience Database Archive (English)

    Full Text Available C 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) - Neofelis nebulosa (Clouded leopard) 4.00E-21 ...

  15. UniProt search blastx result: AK287970 [KOME

    Lifescience Database Archive (English)

    Full Text Available C 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) - Neofelis nebulosa (Clouded leopard) 3.00E-20 ...

  16. UniProt search blastx result: AK287898 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287898 J065210I16 P49889|ST1E3_RAT Estrogen sulfotransferase, isoform 3 (EC 2.8.2....4) (EST-3) (Sulfotransferase, estrogen-preferring) (Estrone sulfotransferase) - Rattus norvegicus (Rat) 1.00E-18 ...

  17. UniProt search blastx result: AK287865 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287865 J065201C22 P49889|ST1E3_RAT Estrogen sulfotransferase, isoform 3 (EC 2.8.2....4) (EST-3) (Sulfotransferase, estrogen-preferring) (Estrone sulfotransferase) - Rattus norvegicus (Rat) 2.00E-28 ...

  18. UniProt search blastx result: AK287898 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287898 J065210I16 P52844|ST1E1_RAT Estrogen sulfotransferase, isoform 1 (EC 2.8.2....4) (EST-1) (Sulfotransferase, estrogen-preferring) (Estrone sulfotransferase) - Rattus norvegicus (Rat) 6.00E-19 ...

  19. UniProt search blastx result: AK287898 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287898 J065210I16 P49890|ST1E6_RAT Estrogen sulfotransferase, isoform 6 (EC 2.8.2....4) (EST-6) (Sulfotransferase, estrogen-preferring) (Estrone sulfotransferase) - Rattus norvegicus (Rat) 2.00E-18 ...

  20. UniProt search blastx result: AK287865 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287865 J065201C22 P52844|ST1E1_RAT Estrogen sulfotransferase, isoform 1 (EC 2.8.2....4) (EST-1) (Sulfotransferase, estrogen-preferring) (Estrone sulfotransferase) - Rattus norvegicus (Rat) 3.00E-28 ...

  1. UniProt search blastx result: AK287865 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287865 J065201C22 P49890|ST1E6_RAT Estrogen sulfotransferase, isoform 6 (EC 2.8.2....4) (EST-6) (Sulfotransferase, estrogen-preferring) (Estrone sulfotransferase) - Rattus norvegicus (Rat) 1.00E-27 ...

  2. UniProt search blastx result: AK287898 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287898 J065210I16 P52845|ST1E2_RAT Estrogen sulfotransferase, isoform 2 (EC 2.8.2....4) (EST-2) (Sulfotransferase, estrogen-preferring) (Estrone sulfotransferase) - Rattus norvegicus (Rat) 2.00E-18 ...

  3. GenBank blastx search result: AK110605 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK110605 002-168-G09 BC097157.1 Danio rerio similar to Myeloid leukemia factor 2 (Myelodysplasia-myeloid leu...kemia factor 2), mRNA (cDNA clone MGC:114097 IMAGE:7448089), complete cds.|VRT VRT 6e-15 +3 ...

  4. UniProt search blastx result: AK287484 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287484 J043026J21 Q90330|FGFR4_COTCO Fibroblast growth factor receptor 4 precurso...r (EC 2.7.10.1) (FGFR-4) (Fibroblast growth factor receptor-like embryonic kinase) - Coturnix coturnix (Common quail) 2.00E-15 ...

  5. UniProt search blastx result: AK287946 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287946 J075022P19 Q90330|FGFR4_COTCO Fibroblast growth factor receptor 4 precurso...r (EC 2.7.10.1) (FGFR-4) (Fibroblast growth factor receptor-like embryonic kinase) - Coturnix coturnix (Common quail) 7.00E-31 ...

  6. UniProt search blastx result: AK288723 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288723 J090063A13 Q90330|FGFR4_COTCO Fibroblast growth factor receptor 4 precurso...r (EC 2.7.10.1) (FGFR-4) (Fibroblast growth factor receptor-like embryonic kinase) - Coturnix coturnix (Common quail) 6.00E-31 ...

  7. GenBank blastx search result: AK287855 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287855 J065196O16 AB091060.1 AB091060 Gluconacetobacter xylinus acsAB, acsC, acsD genes for cellulose... synthase subunit AB, cellulose synthase subunit C, cellulose synthase subunit D, complete cds. BCT 4e-15 0 ...

  8. GenBank blastx search result: AK242831 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK242831 J090067L08 AB091060.1 AB091060 Gluconacetobacter xylinus acsAB, acsC, acsD genes for cellulose... synthase subunit AB, cellulose synthase subunit C, cellulose synthase subunit D, complete cds. BCT 1e-14 1 ...

  9. UniProt search blastx result: AK287732 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287732 J065141C01 Q14576|ELAV3_HUMAN ELAV-like protein 3 (Hu-antigen C) (HuC) (Paraneoplastic... cerebellar degeneration-associated antigen) (Paraneoplastic limbic encephalitis antigen 21) - Homo sapiens (Human) 2.00E-13 ...

  10. UniProt search blastx result: AK288879 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288879 J090079C21 Q14576|ELAV3_HUMAN ELAV-like protein 3 (Hu-antigen C) (HuC) (Paraneoplastic... cerebellar degeneration-associated antigen) (Paraneoplastic limbic encephalitis antigen 21) - Homo sapiens (Human) 2.00E-15 ...

  11. UniProt search blastx result: AK288054 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288054 J075152E14 P16881|RBS_EUGGR Ribulose bisphosphate carboxylase small chains..., chloroplast precursor (EC 4.1.1.39) (RuBisCO small subunits) [Contains: Ribulose bisphosphate carboxylase small chain P1; Ribulos...e bisphosphate carboxylase small chain P2; Ribulose bisphosphate carboxylase small chain P3; Ribulos...e bisphosphate carboxylase small chain P4; Ribulose bisphosphate c...arboxylase small chain P5; Ribulose bisphosphate carboxylase small chain P6; Ribulose bisphosphate carboxylase small chain P7; Ribulo

  12. UniProt search blastx result: AK287599 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287599 J065050G24 P16881|RBS_EUGGR Ribulose bisphosphate carboxylase small chains..., chloroplast precursor (EC 4.1.1.39) (RuBisCO small subunits) [Contains: Ribulose bisphosphate carboxylase small chain P1; Ribulos...e bisphosphate carboxylase small chain P2; Ribulose bisphosphate carboxylase small chain P3; Ribulos...e bisphosphate carboxylase small chain P4; Ribulose bisphosphate c...arboxylase small chain P5; Ribulose bisphosphate carboxylase small chain P6; Ribulose bisphosphate carboxylase small chain P7; Ribulo

  13. UniProt search blastx result: AK288517 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288517 J090043B03 P16881|RBS_EUGGR Ribulose bisphosphate carboxylase small chains..., chloroplast precursor (EC 4.1.1.39) (RuBisCO small subunits) [Contains: Ribulose bisphosphate carboxylase small chain P1; Ribulos...e bisphosphate carboxylase small chain P2; Ribulose bisphosphate carboxylase small chain P3; Ribulos...e bisphosphate carboxylase small chain P4; Ribulose bisphosphate c...arboxylase small chain P5; Ribulose bisphosphate carboxylase small chain P6; Ribulose bisphosphate carboxylase small chain P7; Ribulo

  14. GenBank blastx search result: AK287424 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287424 J043006K04 AF414084.1 AF414084 Corynebacterium crenatum feedback-resistant... aspartokinase LysC alpha subunit and feedback-resistant aspartokinase LysC beta subunit genes, complete cds. BCT 5e-24 0 ...

  15. GenBank blastx search result: AK061941 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK061941 001-042-D10 AF414084.1 Corynebacterium crenatum feedback-resistant asparto...kinase LysC alpha subunit and feedback-resistant aspartokinase LysC beta subunit genes, complete cds.|BCT BCT 2e-34 +2 ...

  16. GenBank blastx search result: AK060750 [KOME

    Lifescience Database Archive (English)

    Full Text Available n 6, a glutamate dehydrogenase 1 (GLUD1) pseudogene and the 3' end of the DCX gene for doublecortex; lissencephaly, X-linked (doublecortin), complete sequence.|PRI PRI 2e-12 +2 ...

  17. GenBank blastx search result: AK242766 [KOME

    Lifescience Database Archive (English)

    Full Text Available r calpain 6, a glutamate dehydrogenase 1 (GLUD1) pseudogene and the 3' end of the DCX gene for doublecortex; lissencephaly, X-linked (doublecortin), complete sequence. PRI 2e-33 1 ...

  18. GenBank blastx search result: AK242717 [KOME

    Lifescience Database Archive (English)

    Full Text Available r calpain 6, a glutamate dehydrogenase 1 (GLUD1) pseudogene and the 3' end of the DCX gene for doublecortex; lissencephaly, X-linked (doublecortin), complete sequence. PRI 2e-37 1 ...

  19. GenBank blastx search result: AK058518 [KOME

    Lifescience Database Archive (English)

    Full Text Available n 6, a glutamate dehydrogenase 1 (GLUD1) pseudogene and the 3' end of the DCX gene for doublecortex; lissencephaly, X-linked (doublecortin), complete sequence.|PRI PRI 1e-24 +2 ...

  20. UniProt search blastx result: AK289070 [KOME

    Lifescience Database Archive (English)

    Full Text Available ol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Contains: Capsid protein (CA) (p24); Spacer peptide p3; Nucleoc...apsid protein p11 (NC); Ty3 protease (EC 3.4.23.-) (PR) (p16); Spacer peptide J; Reverse transcriptase/ribon

  1. UniProt search blastx result: AK289070 [KOME

    Lifescience Database Archive (English)

    Full Text Available ol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Contains: Capsid protein (CA) (p24); Spacer peptide p3; Nucleoc...apsid protein p11 (NC); Ty3 protease (EC 3.4.23.-) (PR) (p16); Spacer peptide J; Reverse transcriptase/ribon

  2. UniProt search blastx result: AK288702 [KOME

    Lifescience Database Archive (English)

    Full Text Available ol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Contains: Capsid protein (CA) (p24); Spacer peptide p3; Nucleoc...apsid protein p11 (NC); Ty3 protease (EC 3.4.23.-) (PR) (p16); Spacer peptide J; Reverse transcriptase/ribon

  3. GenBank blastx search result: AK110466 [KOME

    Lifescience Database Archive (English)

    Full Text Available or general transcription factor IIH, polypeptide 4, 52kDa, the VARS2L gene for valyl-tRNA synthetase 2-like, the SFTPG gene for surfa...ctant associated protein G, the HCG21 gene for HLA compl

  4. GenBank blastx search result: AK110360 [KOME

    Lifescience Database Archive (English)

    Full Text Available or general transcription factor IIH, polypeptide 4, 52kDa, the VARS2L gene for valyl-tRNA synthetase 2-like, the SFTPG gene for surfa...ctant associated protein G, the HCG21 gene for HLA compl

  5. GenBank blastx search result: AK288287 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288287 J090018F21 AY740525.1 AY740525 Tetrahymena thermophila cadmium-inducible m...etallothionein 1 (MTT1) and cadmium-inducible metallothionein 3 (MTT3) genes, complete cds. INV 0.0 0 ...

  6. GenBank blastx search result: AK242967 [KOME

    Lifescience Database Archive (English)

    Full Text Available nsitive, 1, a gene for novel protein similar to human and rodent member RAS oncogene family RAB7 (RAB7), a gene for novel protein rem...otely similar to human host cell factor 1 (VP16-accessor

  7. GenBank blastx search result: AK287609 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK287609 J065058I05 BC076927.1 BC076927 Xenopus tropicalis matrix metalloproteinase 9 (gelatin...ase B, 92kDa gelatinase, 92kDa type IV collagenase), mRNA (cDNA clone MGC:89173 IMAGE:7016488), complete cds. VRT 3e-13 0 ...

  8. GenBank blastx search result: AK105069 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK105069 001-045-C01 AB169286.1 Macaca fascicularis testis cDNA, clone: QtsA-18648, similar to human mortali...ty factor 4 like 2 (MORF4L2), mRNA, RefSeq: NM_012286.1.|PRI PRI 3e-20 +3 ...

  9. GenBank blastx search result: AK060364 [KOME

    Lifescience Database Archive (English)

    Full Text Available CoA hydratase (badk), cyclohex-1-ene-1-carboxylate CoA ligase (aliA), cyclohexanecarboxyl-CoA dehydrogenase (badJ), 2-ketocyclohexane...carboxyl-CoA hydrolase (badI), putative 2-hydroxycyclohexanecarboxyl-CoA dehydrogen

  10. GenBank blastx search result: AK242840 [KOME

    Lifescience Database Archive (English)

    Full Text Available arboxyl-CoA hydratase (badk), cyclohex-1-ene-1-carboxylate CoA ligase (aliA), cyclohexanecarboxyl-CoA dehydr...ogenase (badJ), 2-ketocyclohexanecarboxyl-CoA hydrolase (badI), putative 2-hydroxycyclohexanecarboxyl-CoA de

  11. GenBank blastx search result: AK105359 [KOME

    Lifescience Database Archive (English)

    Full Text Available CoA hydratase (badk), cyclohex-1-ene-1-carboxylate CoA ligase (aliA), cyclohexanecarboxyl-CoA dehydrogenase (badJ), 2-ketocyclohexane...carboxyl-CoA hydrolase (badI), putative 2-hydroxycyclohexanecarboxyl-CoA dehydrogen

  12. UniProt search blastx result: AK288537 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288537 J090045J06 Q8BH47|SC22A_MOUSE Vesicle-trafficking protein SEC22a (SEC22 vesicle-trafficking... protein homolog A) (SEC22 vesicle-trafficking protein-like 2) - Mus musculus (Mouse) 1.00E-15 ...

  13. UniProt search blastx result: AK288537 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288537 J090045J06 Q642F4|SC22A_RAT Vesicle-trafficking protein SEC22a (SEC22 vesicle-trafficking... protein homolog A) (SEC22 vesicle-trafficking protein-like 2) (rSec22a) - Rattus norvegicus (Rat) 9.00E-15 ...

  14. UniProt search blastx result: AK288537 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288537 J090045J06 O75396|SC22B_HUMAN Vesicle-trafficking protein SEC22b (SEC22 vesicle-trafficking... protein homolog B) (SEC22 vesicle-trafficking protein-like 1) (ERS24) (ERS-24) - Homo sapiens (Human) 5.00E-49 ...

  15. UniProt search blastx result: AK288537 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288537 J090045J06 Q96IW7|SC22A_HUMAN Vesicle-trafficking protein SEC22a (SEC22 vesicle-trafficking... protein homolog A) (SEC22 vesicle-trafficking protein-like 2) - Homo sapiens (Human) 2.00E-15 ...

  16. UniProt search blastx result: AK288537 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288537 J090045J06 Q4KM74|SC22B_RAT Vesicle-trafficking protein SEC22b (SEC22 vesicle-trafficking... protein homolog B) (SEC22 vesicle-trafficking protein-like 1) (ERS24) (ERS-24) - Rattus norvegicus (Rat) 5.00E-49 ...

  17. UniProt search blastx result: AK288537 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288537 J090045J06 Q5RAI9|SC22B_PONPY Vesicle-trafficking protein SEC22b (SEC22 vesicle-trafficking... protein homolog B) (SEC22 vesicle-trafficking protein-like 1) - Pongo pygmaeus (Orangutan) 5.00E-49 ...

  18. GenBank blastx search result: AK105716 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK105716 001-201-F04 CR457266.1 Homo sapiens full open reading frame cDNA clone RZP...Do834C046D for gene C20orf31, chromosome 20 open reading frame 31; complete cds, incl. stopcodon.|PRI PRI 1e-90 +1 ...

  19. GenBank blastx search result: AK288392 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK288392 J090027K17 CR457179.1 CR457179 Homo sapiens full open reading frame cDNA c...lone RZPDo834D108D for gene C15orf15, chromosome 15 open reading frame 15; complete cds, incl. stopcodon. PRI 1e-39 0 ...

  20. GenBank blastx search result: AK059388 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK059388 001-026-H03 CR457345.1 Homo sapiens full open reading frame cDNA clone RZP...Do834B0510D for gene C14orf137, chromosome 14 open reading frame 137; complete cds, incl. stopcodon.|PRI PRI 1e-28 +3 ...

  1. GenBank blastx search result: AK107489 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK107489 002-129-C12 CR457345.1 Homo sapiens full open reading frame cDNA clone RZP...Do834B0510D for gene C14orf137, chromosome 14 open reading frame 137; complete cds, incl. stopcodon.|PRI PRI 1e-14 +1 ...

  2. GenBank blastx search result: AK060852 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK060852 001-034-E10 CR457266.1 Homo sapiens full open reading frame cDNA clone RZP...Do834C046D for gene C20orf31, chromosome 20 open reading frame 31; complete cds, incl. stopcodon.|PRI PRI 3e-33 +3 ...

  3. GenBank blastx search result: AK105170 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK105170 001-104-F07 AF148542.1 Arabidopsis thaliana cyclic nucleotide-binding transporter 2 (CNBT...2) and cyclic nucleotide-binding transporter 1 (CNBT1) genes, complete cds.|PLN PLN 7e-28 +1 ...

  4. GenBank blastx search result: AK060339 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK060339 001-008-C12 AF148542.1 Arabidopsis thaliana cyclic nucleotide-binding transporter 2 (CNBT...2) and cyclic nucleotide-binding transporter 1 (CNBT1) genes, complete cds.|PLN PLN 3e-53 +1 ...

  5. GenBank blastx search result: AK241861 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK241861 J065216G16 AF148542.1 AF148542 Arabidopsis thaliana cyclic nucleotide-binding transporter 2 (CNBT...2) and cyclic nucleotide-binding transporter 1 (CNBT1) genes, complete cds. PLN 0.0 1 ...

  6. GenBank blastx search result: AK059452 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK059452 001-028-B08 AF148542.1 Arabidopsis thaliana cyclic nucleotide-binding transporter 2 (CNBT...2) and cyclic nucleotide-binding transporter 1 (CNBT1) genes, complete cds.|PLN PLN 1e-86 +3 ...

  7. GenBank blastx search result: AK243602 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK243602 J100084P18 AF148542.1 AF148542 Arabidopsis thaliana cyclic nucleotide-binding transporter 2 (CNBT...2) and cyclic nucleotide-binding transporter 1 (CNBT1) genes, complete cds. PLN 2e-97 1 ...

  8. GenBank blastx search result: AK119931 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK119931 002-184-A07 AF148542.1 Arabidopsis thaliana cyclic nucleotide-binding transporter 2 (CNBT...2) and cyclic nucleotide-binding transporter 1 (CNBT1) genes, complete cds.|PLN PLN 2e-23 +1 ...

  9. GenBank blastx search result: AK112041 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK112041 001-044-H11 AF148542.1 Arabidopsis thaliana cyclic nucleotide-binding transporter 2 (CNBT...2) and cyclic nucleotide-binding transporter 1 (CNBT1) genes, complete cds.|PLN PLN 4e-49 +2 ...

  10. GenBank blastx search result: AK243221 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK243221 J100043L21 AF148542.1 AF148542 Arabidopsis thaliana cyclic nucleotide-binding transporter 2 (CNBT...2) and cyclic nucleotide-binding transporter 1 (CNBT1) genes, complete cds. PLN 3e-47 1 ...

  11. GenBank blastx search result: AK241821 [KOME

    Lifescience Database Archive (English)

    Full Text Available dependent regulator of chromatin (subfamily a, member 1), the 5' end of the OCRL gene for oculocerebrorenal syndrome of Lowe and two CpG islands, complete sequence. PRI 5e-41 1 ...

  12. GenBank blastx search result: AK241408 [KOME

    Lifescience Database Archive (English)

    Full Text Available dependent regulator of chromatin (subfamily a, member 1), the 5' end of the OCRL gene for oculocerebrorenal syndrome of Lowe and two CpG islands, complete sequence. PRI 1e-21 1 ...

  13. GenBank blastx search result: AK058642 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK058642 001-018-E05 AF023268.1 Homo sapiens clk2 kinase (CLK2), propin1, cote1, glucocerebro...sidase (GBA), and metaxin genes, complete cds; metaxin pseudogene and glucocerebrosidase pseudogene; and thrombospondin3 (THBS3) gene, partial cds.|PRI PRI 2e-18 +3 ...

  14. GenBank blastx search result: AK059494 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK059494 001-028-H05 AB179082.1 Macaca fascicularis testis cDNA clone: QtsA-12630, similar to human oculocer...ebrorenal syndrome of Lowe (OCRL), transcriptvariant a, mRNA, RefSeq: NM_000276.3.|PRI PRI 7e-40 +2 ...

  15. GenBank blastx search result: AK104229 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK104229 006-307-D03 AF023268.1 Homo sapiens clk2 kinase (CLK2), propin1, cote1, glucocerebro...sidase (GBA), and metaxin genes, complete cds; metaxin pseudogene and glucocerebrosidase pseudogene; and thrombospondin3 (THBS3) gene, partial cds.|PRI PRI 3e-41 +3 ...

  16. GenBank blastx search result: AK106998 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK106998 002-120-B12 AB179082.1 Macaca fascicularis testis cDNA clone: QtsA-12630, similar to human oculocer...ebrorenal syndrome of Lowe (OCRL), transcriptvariant a, mRNA, RefSeq: NM_000276.3.|PRI PRI 1e-29 +3 ...

  17. GenBank blastx search result: AK061708 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK061708 001-037-F11 AF023268.1 Homo sapiens clk2 kinase (CLK2), propin1, cote1, glucocerebro...sidase (GBA), and metaxin genes, complete cds; metaxin pseudogene and glucocerebrosidase pseudogene; and thrombospondin3 (THBS3) gene, partial cds.|PRI PRI 1e-41 +3 ...

  18. GenBank blastx search result: AK242828 [KOME

    Lifescience Database Archive (English)

    Full Text Available dependent regulator of chromatin (subfamily a, member 1), the 5' end of the OCRL gene for oculocerebrorenal syndrome of Lowe and two CpG islands, complete sequence. PRI 3e-51 1 ...

  19. GenBank blastx search result: AK241034 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK241034 J065058O11 AL020991.1 HS884M20 Human DNA sequence from clone RP5-884M20 on chromosome Xp11.21 Contains the ALAS2 gene for aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia), the APEX2 gene for APEX nuclease (apurinic/apyrimidinic endonuclease) 2, the 5' end of the PFKFB1 gene for 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 and a CpG island, complete sequence. PRI 2e-34 1 ...

  20. GenBank blastx search result: AK110598 [KOME

    Lifescience Database Archive (English)

    Full Text Available ene/o-xylene monooxygenase (touABCDEF), putative gene encoding a transposase, ORF1 and ORF2 DNA and touR gene encoding sigma 54-dependent transcriptional activator.|BCT BCT 7e-80 +2 ...

  1. GenBank blastx search result: AK103964 [KOME

    Lifescience Database Archive (English)

    Full Text Available ene/o-xylene monooxygenase (touABCDEF), putative gene encoding a transposase, ORF1 and ORF2 DNA and touR gene encoding sigma 54-dependent transcriptional activator.|BCT BCT 9e-11 +3 ...

  2. GenBank blastx search result: AK058594 [KOME

    Lifescience Database Archive (English)

    Full Text Available ene/o-xylene monooxygenase (touABCDEF), putative gene encoding a transposase, ORF1 and ORF2 DNA and touR gene encoding sigma 54-dependent transcriptional activator.|BCT BCT 9e-11 +3 ...

  3. GenBank blastx search result: AK061686 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK061686 001-037-B01 AB032523.1 Streptomyces avermitilis avermectin biosynthetic gene cluster (orf1, ave...BI, aveBII, aveBIII, aveBIV, aveBV, aveBVI, aveBVII, aveBVIII), complete cds.|BCT BCT 2e-22 +3 ...

  4. GenBank blastx search result: AK060737 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK060737 001-032-C07 AB032523.1 Streptomyces avermitilis avermectin biosynthetic gene cluster (orf1, ave...BI, aveBII, aveBIII, aveBIV, aveBV, aveBVI, aveBVII, aveBVIII), complete cds.|BCT BCT 5e-12 +2 ...

  5. GenBank blastx search result: AK241876 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK241876 J065218G08 AB032523.1 AB032523 Streptomyces avermitilis avermectin biosynt...hetic gene cluster (orf1, aveBI, aveBII, aveBIII, aveBIV, aveBV, aveBVI, aveBVII, aveBVIII), complete cds. BCT 5e-24 1 ...

  6. GenBank blastx search result: AK243016 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK243016 J090098K14 AB032523.1 AB032523 Streptomyces avermitilis avermectin biosynt...hetic gene cluster (orf1, aveBI, aveBII, aveBIII, aveBIV, aveBV, aveBVI, aveBVII, aveBVIII), complete cds. BCT 3e-12 1 ...

  7. GenBank blastx search result: AK061857 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK061857 001-040-G06 AB032523.1 Streptomyces avermitilis avermectin biosynthetic gene cluster (orf1, ave...BI, aveBII, aveBIII, aveBIV, aveBV, aveBVI, aveBVII, aveBVIII), complete cds.|BCT BCT 9e-14 +2 ...

  8. GenBank blastx search result: AK061807 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK061807 001-040-A04 AB032523.1 Streptomyces avermitilis avermectin biosynthetic gene cluster (orf1, ave...BI, aveBII, aveBIII, aveBIV, aveBV, aveBVI, aveBVII, aveBVIII), complete cds.|BCT BCT 7e-11 +2 ...

  9. UniProt search blastx result: AK289207 [KOME

    Lifescience Database Archive (English)

    Full Text Available eptococcus asaccharolyticus (Peptococcus asaccharolyticus) 2.00E-74 ... ...AK289207 J100056H18 P28997|DHE2_PEPAS NAD-specific glutamate dehydrogenase (EC 1.4.1.2) (NAD-GDH) - Peptostr

  10. GenBank blastx search result: AK104831 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK104831 001-042-A04 AF157797.1 Pseudomonas sp. R9 transposon Tn1404 hypothetical protein D, hypothetica...l protein C, hypothetical protein B, hypothetical protein E, hypothetical protein F, sulfate permease, hypotheti...cal protein G, and hypothetical protein H genes, complete cds.|BCT BCT 1e-16 +3 ...

  11. GenBank blastx search result: AK241096 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK241096 J065076O13 AF335504.1 AF335504 Oryza sativa (japonica cultivar-group) hemoglobin 1 (hb1), hemoglobi...n 3 (hb3), and hemoglobin 4 (hb4) genes, complete cds. PLN 4e-79 1 ...

  12. GenBank blastx search result: AK240885 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK240885 J065029A17 AF335504.1 AF335504 Oryza sativa (japonica cultivar-group) hemoglobin 1 (hb1), hemoglobi...n 3 (hb3), and hemoglobin 4 (hb4) genes, complete cds. PLN 7e-89 1 ...

  13. Impact of obstetric history on the risk of spontaneous preterm birth in singleton and multiple pregnancies: a systematic review.

    Science.gov (United States)

    Kazemier, B M; Buijs, P E; Mignini, L; Limpens, J; de Groot, C J M; Mol, B W J

    2014-09-01

    Information about the recurrence of spontaneous preterm birth in subsequent twin/singleton pregnancies is scattered. To quantify the risk of recurrence of spontaneous preterm birth in different subtypes of subsequent pregnancies. An electronic literature search in OVID MEDLINE and EMBASE, complemented by PubMed, to find recent studies. Studies comparing the risk of spontaneous preterm birth after a previous preterm and previous term pregnancy. The absolute risk of recurrence with a 95% confidence interval and the absolute risk of preterm birth after a term delivery were calculated. Data from studies were pooled using the Mantel-Haenszel method. We detected 13 relevant studies. The risk of recurrence of preterm birth was significantly increased in all preterm pregnancy subtypes, compared with their term counterparts. Women pregnant with twins after a previous preterm singleton had the highest absolute risk of recurrence (57.0%, 95% CI 51.9-61.9%), and after a previous term singleton their absolute risk was 25% (95% CI 24.3-26.5%). Women pregnant with a singleton after a previous preterm twin pregnancy have an absolute recurrence risk of 10% (95% CI 8.2-12.3%), whereas a singleton pregnancy after delivering a previous twin up to term yields a low absolute risk of only 1.3% (95% CI 0.8-2.2). Women pregnant with a singleton after a previous preterm singleton have an absolute recurrence risk of 20% (95% CI 19.9-20.6). The risk of recurrence of preterm birth is influenced by the singleton/twin order in both pregnancies, and varies between 10% for a singleton after previous preterm twins to 57% for twins after a previous preterm singleton. © 2014 Royal College of Obstetricians and Gynaecologists.

  14. Singleton status and childhood obesity: Investigating effects and mechanisms Status :

    OpenAIRE

    Maoyong Fan; Yanhong Jin

    2015-01-01

    Over the past four decades, paralleling the increasing prevalence of childhood obesity, the share of families with only one child has been rising steadily. Using three waves of the National Survey of Children's Health, we examine the effect of being the only child in a family on childhood obesity and the mechanisms through which singleton status might affect childhood obesity. We find gender-specific and age-dependent singleton effects. That is, singletons have a higher level of body mass ind...

  15. Comparison of academic performance of twins and singletons in adolescence

    DEFF Research Database (Denmark)

    Christensen, Kaare; Petersen, Inge; Skytthe, Axel

    2006-01-01

    OBJECTIVES: To determine whether twins in recent cohorts show similar academic performance in adolescence to singletons and to test the effect of birth weight on academic performance in twins and singletons. DESIGN: Follow-up study. SETTING: Denmark. PARTICIPANTS: All twins (n=3411) and a 5% random...... increase in birth weight. CONCLUSIONS: Although older cohorts of twins have been found to have lower mean IQ scores than singletons, twins in recent Danish cohorts show similar academic performance in adolescence to that of singletons. Birth weight has a minimal effect on academic performance in recent...

  16. Pregnancy outcome in singleton term breeches from a referral ...

    African Journals Online (AJOL)

    Objective: To compare the pregnancy outcome in women with singleton breech presentation at term delivered by caesarean section (CS) and vaginal breech delivery. Design: A retrospective study. Setting: Abha Maternity hospital, Saudi Arabia. Material and Methods: 573 women with singleton breech presentation at term ...

  17. SHIVGAMI : Simplifying tHe titanIc blastx process using aVailable GAthering of coMputational unIts

    Directory of Open Access Journals (Sweden)

    Naman Mangukia

    2017-10-01

    Full Text Available Assembling novel genomes from scratch is a never ending process unless and until the homo sapiens cover all the living organisms! On top of that, this denovo approach is employed by RNASeq and Metagenomics analysis. Functional identification of the scaffolds or transcripts from such drafted assemblies is a substantial step routinely employes a well-known BlastX program which facilitates a user to search DNA query against NCBI-Protein (NR:~120Gb database. In spite of having multicore-processing option, blastX is an elongated process for the bulk of lengthy Queryinputs. Tremendous efforts are constantly being applied to solve this problem by increasing computational power, GPU-Based computing, Cloud computing and Hadoop based approach which ultimately requires gigantic cost in terms of money and processing. To address this issue, here we have come up with SHIVGAMI, which automates the entire process using perl and shell scripts, which divide, distribute and process the input FASTA sequences as per the CPU-cores availability amongst the computational units individually. Linux operating system, NR database and blastX program installations are prerequisites for each system.  The beauty of this stand-alone automation program SHIVGAMI is it requires the LAN connection exactly twice: During ‘query distribution’ and at the time of ‘proces completion’. In initial phase, it divides the fasta sequences according to the individual computer's core-capability. Then it will evenly distribute all the data along with small automation scripts which will run the blastX process to the respective computational unit and send back the results file to the master computer. The master computer finally combines and compiles the files into a single result. This simple automation converts a computer lab into a GRID without investment of any software, hardware and man-power. In short, SHIVGAMI is a time and cost savior tool for all users starting from commercial firm

  18. Vanishing twin syndrome among ART singletons and pregnancy outcomes.

    Science.gov (United States)

    Magnus, Maria C; Ghaderi, Sara; Morken, Nils-Halvdan; Magnus, Per; Bente Romundstad, Liv; Skjærven, Rolv; Wilcox, Allen J; Eldevik Håberg, Siri

    2017-11-01

    Among babies born by ART, do singleton survivors of a vanishing twin have lower birth weight than other singletons? Vanishing twin syndrome (VTS) was associated with lower birth weight among ART singletons; a sibship analysis indicated that the association was not confounded by maternal characteristics that remain stable between deliveries. Previous studies indicate that ART singletons with VTS have increased risk of adverse pregnancy outcomes, compared with other ART singletons. The potential contribution of unmeasured maternal background characteristics has been unclear. This was a Norwegian population-based registry study, including 17 368 mothers with 20 410 ART singleton deliveries between January 1984 and December 2013. The study population included 17 291 ART singletons without VTS, 638 ART singletons with VTS and 2418 ART singletons with uncertain vanishing twin status. We estimated differences in birth weight and gestational age comparing ART singletons with VTS first to all ART singletons without VTS, and subsequently to their ART siblings without VTS, using random- and fixed-effects linear regression, respectively. The corresponding comparisons for the associations with preterm birth and small for gestational age (SGA) were conducted using random-and fixed-effects logistic regression. The sibling analysis of preterm birth included 587 discordant siblings, while the sibling analysis of SGA included 674 discordant siblings. ART singletons with VTS had lower birth weight when compared to all ART singletons without VTS, with an adjusted mean difference (95% CI) of -116 g (-165, -67). When we compared ART singletons with VTS to their ART singletons sibling without VTS, the adjusted mean difference was -112 g (-209, -15). ART singletons with VTS also had increased risk of being born SGA, with an adjusted odds ratio (OR) (95% CI) of 1.48 (1.07, 2.03) compared to all ART singletons without VTS, and 2.79 (1.12, 6.91) in the sibship analyses. ART singletons with

  19. Impact of obstetric history on the risk of spontaneous preterm birth in singleton and multiple pregnancies: a systematic review

    NARCIS (Netherlands)

    Kazemier, B. M.; Buijs, P. E.; Mignini, L.; Limpens, J.; de Groot, C. J. M.; Mol, B. W. J.; von Dadelszen, P.; Magee, L.; Sawchuck, D.; Gao, E.; Oude Rengerink, K.; Zamora, J.; Fox, C.; Daniels, J.; Khan, K. S.; Thangaratinam, S.; Meads, C.

    2014-01-01

    Information about the recurrence of spontaneous preterm birth in subsequent twin/singleton pregnancies is scattered. To quantify the risk of recurrence of spontaneous preterm birth in different subtypes of subsequent pregnancies. An electronic literature search in OVID MEDLINE and EMBASE,

  20. SEARCH

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chaitali Sinha

    Anexo B: Lista de verificación para presentar una nota conceptual en el marco de IDRC-SEARCH ....... 17 .... incluir investigación primaria y/o síntesis de estudios existentes, para generar nuevo conocimiento. Los .... de datos entre grupos diferentes de usuarios (trabajadores de la salud comunitaria, funcionarios de salud.

  1. Vaginal progesterone for preventing preterm birth and adverse perinatal outcomes in singleton gestations with a short cervix: a meta-analysis of individual patient data.

    Science.gov (United States)

    Romero, Roberto; Conde-Agudelo, Agustin; Da Fonseca, Eduardo; O'Brien, John M; Cetingoz, Elcin; Creasy, George W; Hassan, Sonia S; Nicolaides, Kypros H

    2018-02-01

    The efficacy of vaginal progesterone for preventing preterm birth and adverse perinatal outcomes in singleton gestations with a short cervix has been questioned after publication of the OPPTIMUM study. To determine whether vaginal progesterone prevents preterm birth and improves perinatal outcomes in asymptomatic women with a singleton gestation and a midtrimester sonographic short cervix. We searched MEDLINE, EMBASE, LILACS, and CINAHL (from their inception to September 2017); Cochrane databases; bibliographies; and conference proceedings for randomized controlled trials comparing vaginal progesterone vs placebo/no treatment in women with a singleton gestation and a midtrimester sonographic cervical length ≤25 mm. This was a systematic review and meta-analysis of individual patient data. The primary outcome was preterm birth preterm birth preterm birth preterm birth preterm birth and improves perinatal outcomes in singleton gestations with a midtrimester sonographic short cervix, without any demonstrable deleterious effects on childhood neurodevelopment. Published by Elsevier Inc.

  2. Congenital Malformations in Singleton Infants Conceived by Assisted Reproductive Technologies and Singleton Infants by Natural Conception in Tehran, Iran

    Directory of Open Access Journals (Sweden)

    Ramin Mozafari Kermani

    2017-10-01

    Full Text Available Background: Multiple pregnancies occur more frequently in assisted reproductive technology (ART compared to normal conception (NC. It is known that the risk of congenital malformations in a multiple pregnancy are higher than single pregnancy. The aim of this study is to compare congenital malformations in singleton infants conceived by ART to singleton infants conceived naturally. Materials and Methods: In this historical cohort study, we performed a historical cohort study of major congenital malformations (MCM in 820 singleton births from January 2012 to December 2014. The data for this analysis were derived from Tehran’s ART linked data file. The risk of congenital malformations was compared in 164 ART infants and 656 NC infants. We performed multiple logistic regression analyses for the independent association of ART on each outcome. Results: We found 40 infants with MCM 29 (4.4% NC infants and 14 (8.3% ART infants. In comparison with NC infants, ART infants had a significant 2-fold increased risk of MCM (P=0.046. After adjusting individually for maternal age, infant gender, prior stillbirth, mother’s history of spontaneous abortion, and type of delivery, we did not find any difference in risk. In this study the majority (95.1% of all infants were normal but 4.9% of infants had at least one MCM. We found a difference in risk of MCMs between in vitro fertilization (IVF and intracytoplasmic sperm injection (ICSI. We excluded the possible role of genotype and other unknown factors in causing more malformations in ART infants. Conclusion: This study reported a higher risk of MCMs in ART singleton infants than in NC singleton infants. Congenital heart disease, developmental dysplasia of the hip (DDH, and urogenital malformations were the most reported major malformations in singleton ART infants according to organ and system classification.

  3. Singleton preterm births in Korle bu teaching hospital, Accra, Ghana ...

    African Journals Online (AJOL)

    Objective: To determine the singleton preterm birth rate, the relative proportions of the clinical categories of preterm births and to compare the outcomes in these categories. Setting: Department of Obstetrics & Gynaecol-ogy, Korle Bu Teaching Hospital. Participants: Preterm births from 1st July to 31st December 2003.

  4. The analysis of singletons in generalized birthday problems

    NARCIS (Netherlands)

    Koot, M.R.; Mandjes, M.R.H.

    2012-01-01

    This paper describes techniques to characterize the number of singletons in the setting of the generalized birthday problem, that is, the birthday problem in which the birthdays are non-uniformly distributed over the year. Approximations for the mean and variance presented which explicitly indicate

  5. Pregnancy outcome in singleton term breeches from a referral ...

    African Journals Online (AJOL)

    It is recommended that attention should be given to trainee obstetrician in selective external cephalic version at term and also the procedure of AVBD so as to reduce the caesarean section rate and also neonatal morbidity in term breeches in our community. Keywords: Pregnancy outcome, Singleton breech, Vaginal ...

  6. Study of Perineal Tears During Delivery of Singletons in Cephalic ...

    African Journals Online (AJOL)

    Study of Perineal Tears During Delivery of Singletons in Cephalic Presentation. E Nkwabong, L Kouam, GT Orock, MR Ekono, W Takang, KV Mve. Abstract. Background: Perineal lacerations are associated with short and long term maternal complications like perineal pain and superficial dyspareunia and must be prevented ...

  7. No. 261-Prenatal Screening for Fetal Aneuploidy in Singleton Pregnancies.

    Science.gov (United States)

    Chitayat, David; Langlois, Sylvie; Wilson, R Douglas

    2017-09-01

    To develop a Canadian consensus document on maternal screening for fetal aneuploidy (e.g., Down syndrome and trisomy 18) in singleton pregnancies. Pregnancy screening for fetal aneuploidy started in the mid 1960s, using maternal age as the screening test. New developments in maternal serum and ultrasound screening have made it possible to offer all pregnant patients a non-invasive screening test to assess their risk of having a fetus with aneuploidy to determine whether invasive prenatal diagnostic testing is necessary. This document reviews the options available for non-invasive screening and makes recommendations for Canadian patients and health care workers. To offer non-invasive screening for fetal aneuploidy (trisomy 13, 18, 21) to all pregnant women. Invasive prenatal diagnosis would be offered to women who screen above a set risk cut-off level on non-invasive screening or to pregnant women whose personal, obstetrical, or family history places them at increased risk. Currently available non-invasive screening options include maternal age combined with one of the following: (1) first trimester screening (nuchal translucency, maternal age, and maternal serum biochemical markers), (2) second trimester serum screening (maternal age and maternal serum biochemical markers), or (3) 2-step integrated screening, which includes first and second trimester serum screening with or without nuchal translucency (integrated prenatal screen, serum integrated prenatal screening, contingent, and sequential). These options are reviewed, and recommendations are made. Studies published between 1982 and 2009 were retrieved through searches of PubMed or Medline and CINAHL and the Cochrane Library, using appropriate controlled vocabulary and key words (aneuploidy, Down syndrome, trisomy, prenatal screening, genetic health risk, genetic health surveillance, prenatal diagnosis). Results were restricted to systematic reviews, randomized controlled trials, and relevant observational

  8. Prenatal screening for fetal aneuploidy in singleton pregnancies.

    Science.gov (United States)

    Chitayat, David; Langlois, Sylvie; Douglas Wilson, R

    2011-07-01

    To develop a Canadian consensus document on maternal screening for fetal aneuploidy (e.g., Down syndrome and trisomy 18) in singleton pregnancies. Pregnancy screening for fetal aneuploidy started in the mid 1960s, using maternal age as the screening test. New developments in maternal serum and ultrasound screening have made it possible to offer all pregnant patients a non-invasive screening test to assess their risk of having a fetus with aneuploidy to determine whether invasive prenatal diagnostic testing is necessary. This document reviews the options available for non-invasive screening and makes recommendations for Canadian patients and health care workers. To offer non-invasive screening for fetal aneuploidy (trisomy 13, 18, 21) to all pregnant women. Invasive prenatal diagnosis would be offered to women who screen above a set risk cut-off level on non-invasive screening or to pregnant women whose personal, obstetrical, or family history places them at increased risk. Currently available non-invasive screening options include maternal age combined with one of the following: (1) first trimester screening (nuchal translucency, maternal age, and maternal serum biochemical markers), (2) second trimester serum screening (maternal age and maternal serum biochemical markers), or (3) 2-step integrated screening, which includes first and second trimester serum screening with or without nuchal translucency (integrated prenatal screen, serum integrated prenatal screening, contingent, and sequential). These options are reviewed, and recommendations are made. Studies published between 1982 and 2009 were retrieved through searches of PubMed or Medline and CINAHL and the Cochrane Library, using appropriate controlled vocabulary and key words (aneuploidy, Down syndrome, trisomy, prenatal screening, genetic health risk, genetic health surveillance, prenatal diagnosis). Results were restricted to systematic reviews, randomized controlled trials, and relevant observational

  9. Evaluation of a hybrid approach using UBLAST and BLASTX for metagenomic sequences annotation of specific functional genes.

    Directory of Open Access Journals (Sweden)

    Ying Yang

    Full Text Available The fast development of next generation sequencing (NGS has dramatically increased the application of metagenomics in various aspects. Functional annotation is a major step in the metagenomics studies. Fast annotation of functional genes has been a challenge because of the deluge of NGS data and expanding databases. A hybrid annotation pipeline proposed previously for taxonomic assignments was evaluated in this study for metagenomic sequences annotation of specific functional genes, such as antibiotic resistance genes, arsenic resistance genes and key genes in nitrogen metabolism. The hybrid approach using UBLAST and BLASTX is 44-177 times faster than direct BLASTX in the annotation using the small protein database for the specific functional genes, with the cost of missing a small portion (<1.8% of target sequences compared with direct BLASTX hits. Different from direct BLASTX, the time required for specific functional genes annotation using the hybrid annotation pipeline depends on the abundance for the target genes. Thus this hybrid annotation pipeline is more suitable in specific functional genes annotation than in comprehensive functional genes annotation.

  10. Amnioreduction in the management of polyhydramnios complicating singleton pregnancies.

    Science.gov (United States)

    Dickinson, Jan Elizabeth; Tjioe, Yan Yan; Jude, Emily; Kirk, Daniel; Franke, Malcolm; Nathan, Elizabeth

    2014-10-01

    The purpose of this study was to evaluate the contribution of amnioreduction to the management of singleton pregnancies that are complicated by symptomatic polyhydramnios. Retrospective review of all singleton pregnancies that received at least 1 amnioreduction for polyhydramnios from 2000-2012 at a single obstetric unit that provides a statewide service. The indications, procedural techniques, and pregnancy outcomes were evaluated. One hundred thirty-eight women with polyhydramnios (maximal vertical pocket [MVP], ≥8 cm) had 271 amnioreduction procedures during the study period. The median gestation at the first drain was 31.4 weeks (interquartile range, 28.4-34 weeks) and a median of 1 procedure (interquartile range, 1-2 procedures) was performed per pregnancy. Sixty-three women (45.6%) required >1 amnioreduction. The median volume removed per pregnancy was 2100 mL (interquartile range, 1500-4260 mL). The median duration from the first amnioreduction until delivery was 26 days (interquartile range, 15-52.5 days). There was no significant association between gestation at delivery and the volume per procedure or total volume that was removed. Earlier gestation at first drain was associated positively with earlier gestations at delivery. In 4.1% of amnioreduction procedures (11/271 procedures), there was an unplanned preterm birth within 48 hours. The median gestation at delivery was 36.4 weeks (interquartile range, 34-38 weeks). The final diagnoses were gastrointestinal malformations (21%), idiopathic polyhydramnios (20.3%), chromosomal anomaly (15.2%), syndromic condition (13.7%), and neurologic condition (8%). Amnioreduction has a useful role in the management of polyhydramnios in singleton pregnancies. Complications are uncommon, and delivery typically occurs near term. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. Sonographic measurement of fetal thymus size in uncomplicated singleton pregnancies.

    Science.gov (United States)

    Tangshewinsirikul, Chayada; Panburana, Panyu

    2017-03-04

    To establish sonographic reference ranges of the normal fetal thymus size between 17 and 38 weeks of gestational age (GA). The study was conducted between April 1 and December 31, 2013. Low-risk singleton pregnancies without obstetrical and medical complications at the GAs between 17 and 38 weeks were recruited for thymus measurement. The fetal thymus was identified on transabdominal sonography at the three-vessel view. Maximal transverse diameter, perimeter, and thymus/thoracic ratio were measured. The best-fit models in predicting thymic dimensions as a function of GA and biparietal diameter (BPD) were determined using regression analysis, and percentile charts for predicting thymic dimensions were constructed. A total of 296 singleton pregnancies were recruited in this study. Maximal transverse diameter, perimeter, and thymus/thoracic ratio increased throughout pregnancy. The regression equation for maximal transverse diameter of the thymus as a function of GA was as follows: Predicted mean thymus diameter (mm) = -25.904 + 2.476 × GA - 0.019 × GA 2 (r = 0.915; p thymus diameter (mm) = 1.428 + 0.044 × GA (r = 0.017; p < 0.001). Sonographic reference ranges of the normal fetal thymic dimensions between 17 and 38 weeks of GA have been established. © 2016 Wiley Periodicals, Inc. J Clin Ultrasound 45:150-159, 2017. © 2016 Wiley Periodicals, Inc.

  12. Hypercoiling of the umbilical cord in uncomplicated singleton pregnancies.

    Science.gov (United States)

    Ma'ayeh, Marwan; McClennen, Evan; Chamchad, Dmitri; Geary, Michael; Brest, Norman; Gerson, Andrew

    2017-06-26

    The umbilical coiling index (UCI) is a measure of the number of coils in the umbilical cord in relation to its length. Hypercoiled cords with a UCI of >0.3 coils/cm have been associated with adverse fetal and neonatal outcomes. The primary aim is to determine the accuracy of UCI measured on second trimester ultrasound in predicting UCI at birth. The secondary outcome is to investigate the association between hypercoiling of the umbilical cord on prenatal ultrasound and adverse maternal, fetal and neonatal outcomes. This was a prospective cohort study of uncomplicated singleton pregnancies. Seventy two patients were included in the study. UCI was measured in the second trimester ultrasound, and compared to UCI measured postnatally. Outcomes of patients with hypercoiled cords on ultrasound were compared to outcomes of patients with normocoiled cords. Our results failed to show a strong correlation between the UCI determined with ultrasound, and the UCI determined with examination of the umbilical cord after delivery. We also did not demonstrate that measurement of the UCI on second trimester ultrasound is able to predict adverse maternal, fetal or neonatal outcomes. This study suggests that measurement of the umbilical coiling index should not be part of routine second trimester sonography in patients with uncomplicated singleton pregnancies, with no other medical or surgical comorbidities.

  13. Overweight in Singletons Compared to Children with Siblings

    DEFF Research Database (Denmark)

    Hunsberger, Monica; Formisano, Annarita; Reisch, Lucia

    2012-01-01

    The aim of this study was to compare the prevalence of overweight in only children to those with siblings and to explore potential behavioral mediating factors. This study relies upon cross-sectional data collected at survey centers in eight European countries participating in Identification....... The three southernmost countries have over threefold risk of overweight, dominated by Italy, compared with the north-central countries, which is not explained by the prevalence of singleton children. The excess risk of overweight among children without siblings was robustly observed even when considering...... and prevention of Dietary- and lifestyle-induced health EFfects In Children and infantS (IDEFICS). The present analysis is based on measured anthropometry and parent or guardian-reported socio-demographic characteristics. Subjects include 12 720 children aged 2–9 years for whom number of siblings was known...

  14. Perinatal outcomes in 6,338 singletons born after intrauterine insemination in Denmark, 2007 to 2012

    DEFF Research Database (Denmark)

    Malchau, Sara Sofia; Loft, Anne; Henningsen, Anna-Karina Aaris

    2014-01-01

    OBJECTIVE: To study perinatal outcomes in singletons born after intrauterine insemination (IUI) compared with children born after in vitro fertilization (IVF), intracytoplasmic sperm injection, and spontaneous conception (SC), and to assess predictors of poor outcome in singletons born after IUI......, exploring the effect of ovarian stimulation. DESIGN: National cohort study, 2007-2012. SETTING: Danish national registries. PATIENT(S): Four thousand two hundred twenty-eight singletons born after insemination with partner semen (IUI-H) and 1,881 singletons born after insemination with donor semen...

  15. Cord around neck in singleton term pregnancies and its outcome

    International Nuclear Information System (INIS)

    Sajjad, R.; Mustafa, N.

    2014-01-01

    To enlist the complications with nuchal cord in singleton term pregnancies and to determine maternal and fetal outcome in singleton term pregnancies. Design: Descriptive study. Place and duration of study: The study was carried out at Gynaecology and Obstetric department Combined Military Hospital Quetta from Nov 2007 to May 2008. Patients and methods: One hundred women irrespective of parity with healthy, singleton term pregnancy and cephalic presentation, labouring or not labouring, were selected from outpatient department. A total of 41 patients were booked with Doppler ultrasound done in antenatal period. Other 59 were poorly booked and diagnosed with cord around neck by clinical criteria e.g. high head at term, fetal distress, meconium discharge, slow progress in labour leading to prolonged labour. All patients signed well informed written proforma regarding study and its outcome. Vigilant feto maternal monitoring was done during labour. All events during labour were mentioned in proformas which were attached with patients case notes. Data was interperated in term of frequency and percentages. Results: Complications with cord around neck found were still birth 3%, fetal distress 15%, intrauterine death 1%. Prolonged labour was seen in 14%, Meconium discharge in 5%, and high presenting part was found in 11% of cases. Maternal outcome were elective caesarean section in 6%, emergency caesarean-section in 32%, spontaneous vaginal delivery in 54% and instrumental vaginal delivery in 8% of the cases. Different fetal outcomes seen were intrauterine death, stillbirth in 1%, and 3% patients respectively. Regarding neonatal outcome, 31% stayed in neonatal intensive care unit (NICU) for less than 48 hours, 69% stayed in NICU for more than 48 hours out of which 4% had early neonatal deaths (ENND). Fifty nine percent patients detected and suspected during labour were with, high head, slow progress in labour, decreased fetal movements, intra partum fetal distress, meconium

  16. Recurrence risk of low Apgar score among term singletons: a population-based cohort study

    NARCIS (Netherlands)

    Ensing, Sabine; Schaaf, Jelle M.; Abu-Hanna, Ameen; Mol, Ben W. J.; Ravelli, Anita C. J.

    2014-01-01

    To examine the risk of recurrence of low Apgar score in a subsequent term singleton pregnancy. Population-based cohort study. The Netherlands. A total of 190,725 women with two subsequent singleton term live births between 1999 and 2007. We calculated the recurrence risk of low Apgar score after

  17. Monozygotic Triplets and a Singleton After ICSI and Day 3 Transfer of Two Embryos

    Directory of Open Access Journals (Sweden)

    Singpetch Suksompong

    2017-07-01

    Full Text Available Monozygotic triplets are a rare condition to occur naturally or even in assisted reproductive technologies. In this report, we present a case of monozygotic triplets with a singleton pregnancy following embryo transfer of 2 embryos. To our knowledge, this is the first published case of one singleton and monozygotic triplets after ICSI and transfer of two day 3 embyos in Thailand.

  18. Recurrence risk of preterm birth in subsequent twin pregnancy after preterm singleton delivery

    NARCIS (Netherlands)

    Schaaf, J. M.; Hof, M. H. P.; Mol, B. W. J.; Abu-Hanna, A.; Ravelli, A. C. J.

    2012-01-01

    Please cite this paper as: Schaaf J, Hof M, Mol B, Abu-Hanna A, Ravelli A. Recurrence risk of preterm birth in subsequent twin pregnancy after preterm singleton delivery.BJOG 2012;119:16241629. Objective To determine the risk of preterm birth in a subsequent twin pregnancy after previous singleton

  19. Recurrence risk of preterm birth in subsequent singleton pregnancy after preterm twin delivery

    NARCIS (Netherlands)

    Schaaf, Jelle M.; Hof, Michel H. P.; Mol, Ben Willem J.; Abu-Hanna, Ameen; Ravelli, Anita C. J.

    2012-01-01

    OBJECTIVE: The purpose of this study was to investigate the recurrence risk of preterm birth ( <37 weeks' gestation) in a subsequent singleton pregnancy after a previous nulliparous preterm twin delivery. STUDY DESIGN: We included 1957 women who delivered a twin gestation and a subsequent singleton

  20. Target-nontarget similarity decreases search efficiency and increases stimulus-driven control in visual search.

    Science.gov (United States)

    Barras, Caroline; Kerzel, Dirk

    2017-10-01

    Some points of criticism against the idea that attentional selection is controlled by bottom-up processing were dispelled by the attentional window account. The attentional window account claims that saliency computations during visual search are only performed for stimuli inside the attentional window. Therefore, a small attentional window may avoid attentional capture by salient distractors because it is likely that the salient distractor is located outside the window. In contrast, a large attentional window increases the chances of attentional capture by a salient distractor. Large and small attentional windows have been associated with efficient (parallel) and inefficient (serial) search, respectively. We compared the effect of a salient color singleton on visual search for a shape singleton during efficient and inefficient search. To vary search efficiency, the nontarget shapes were either similar or dissimilar with respect to the shape singleton. We found that interference from the color singleton was larger with inefficient than efficient search, which contradicts the attentional window account. While inconsistent with the attentional window account, our results are predicted by computational models of visual search. Because of target-nontarget similarity, the target was less salient with inefficient than efficient search. Consequently, the relative saliency of the color distractor was higher with inefficient than with efficient search. Accordingly, stronger attentional capture resulted. Overall, the present results show that bottom-up control by stimulus saliency is stronger when search is difficult, which is inconsistent with the attentional window account.

  1. Subfertility factors rather than assisted conception factors affect cognitive and behavioural development of 4-year-old singletons.

    Science.gov (United States)

    Schendelaar, Pamela; La Bastide-Van Gemert, Sacha; Heineman, Maas Jan; Middelburg, Karin J; Seggers, Jorien; Van den Heuvel, Edwin R; Hadders-Algra, Mijna

    2016-12-01

    Research on cognitive and behavioural development of children born after assisted conception is inconsistent. This prospective study aimed to explore underlying causal relationships between ovarian stimulation, in-vitro procedures, subfertility components and child cognition and behaviour. Participants were singletons born to subfertile couples after ovarian stimulation IVF (n = 63), modified natural cycle IVF (n = 53), natural conception (n = 79) and singletons born to fertile couples (reference group) (n = 98). At 4 years, cognition (Kaufmann-ABC-II; total IQ) and behaviour (Child Behavior Checklist; total problem T-score) were assessed. Causal inference search algorithms and structural equation modelling was applied to unravel causal mechanisms. Most children had typical cognitive and behavioural scores. No underlying causal effect was found between ovarian stimulation and the in-vitro procedure and outcome. Direct negative causal effects were found between severity of subfertility (time to pregnancy) and cognition and presence of subfertility and behaviour. Maternal age and maternal education acted as confounders. The study concludes that no causal effects were found between ovarian stimulation or in-vitro procedures and cognition and behaviour in childrenaged 4 years born to subfertile couples. Subfertility, especially severe subfertility, however, was associated with worse cognition and behaviour. Copyright © 2016 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

  2. Identifying a "default" visual search mode with operant conditioning.

    Science.gov (United States)

    Kawahara, Jun-ichiro

    2010-09-01

    The presence of a singleton in a task-irrelevant domain can impair visual search. This impairment, known as the attentional capture depends on the set of participants. When narrowly searching for a specific feature (the feature search mode), only matching stimuli capture attention. When searching broadly (the singleton detection mode), any oddball captures attention. The present study examined which strategy represents the "default" mode using an operant conditioning approach in which participants were trained, in the absence of explicit instructions, to search for a target in an ambiguous context in which one of two modes was available. The results revealed that participants behaviorally adopted the singleton detection as the default mode but reported using the feature search mode. Conscious strategies did not eliminate capture. These results challenge the view that a conscious set always modulates capture, suggesting that the visual system tends to rely on stimulus salience to deploy attention.

  3. Ovarian hyperstimulation syndrome in a spontaneous singleton pregnancy.

    Science.gov (United States)

    Cabar, Fábio Roberto

    2016-05-24

    The ovarian hyperstimulation syndrome is the combination of increased ovarian volume, due to the presence of multiple cysts and vascular hyperpermeability, with subsequent hypovolemia and hemoconcentration. We report a case of spontaneous syndrome in a singleton pregnancy. This was a spontaneous pregnancy with 12 weeks of gestational age. The pregnancy was uneventful until 11 weeks of gestational age. After that, the pregnant woman complained of progressive abdominal distention associated with abdominal discomfort. She did not report other symptoms. In the first trimester, a routine ultrasonography showed enlarged ovaries, multiples cysts and ascites. Upon admission, the patient was hemodynamically stable, her serum β-hCG was 24,487mIU/mL, thyroid-stimulating hormone was 2.2µUI/mL and free T4 was 1.8ng/dL. All results were within normal parameters. However, levels of estradiol were high (10,562pg/mL). During hospitalization, she received albumin, furosemide and prophylactic dose of enoxaparin. The patient was discharged on the sixth hospital day. RESUMO A síndrome de hiperestimulação ovariana é a combinação do aumento dos ovários, devido à presença de múltiplos cistos e de hiperpermeabilidade vascular, com subsequente hipovolemia e hemoconcentração. Relata-se um caso de síndrome espontânea em uma gestação única. Trata-se de gravidez espontânea com 12 semanas de idade gestacional. A gravidez ocorreu sem intercorrências até 11 semanas de idade gestacional. Após, a gestante passou a se queixar de distensão abdominal progressiva, associada com desconforto abdominal. A paciente não relatava outros sintomas. A ultrassonografia de rotina no primeiro trimestre mostrou ovários aumentados com múltiplos cistos e ascite. No momento da internação, a paciente apresentava-se hemodinamicamente estável, com β-hCG sérico de 24.487mUI/mL, hormônio estimulante da tireoide de 2,2µUI/m e T4 livre de 1,8ng/dL, ou seja, valores dentro dos par

  4. [Incidence of singleton macrosomia in Beijing and its risk factors].

    Science.gov (United States)

    Ren, J H; Wang, C; Wei, Y M; Yang, H X

    2016-06-25

    To evaluate the prevalence of macrosomia in Beijing in 2013 and identify its risk factors. Retrospective six months analysis of 14 188 full-term singleton pregnant women from 15 hospitals with different levels in Beijing in 2013. Each participant's demographic data and medical information were collected individually by questionnaires. Multiple logistic regression analysis was used to examine the associations between variables and the risk of macrosomia. (1)The total prevalence of macrosomia was 7.069% (1 003/14 188) in Beijing in 2013. (2)The prevalence varied between the 15 hospitals, the lowest was 5.36% (89/1 659), while the highest reached 8.80%(46/523). Furthermore, the incidence of macrosomia was 1.284 times (95% CI: 1.114- 1.480, P=0.001) higher in the second graded hospitals than that in the tertiary hospitals. (3) Multiple logistic regression analyses showed that risk factors for macrosomia were maternal height≥160 cm (adjusted OR=1.875, 95% CI: 1.559- 2.256), pre-pregnant body mass index (p-BMI) ≥24.0 kg/m(2) (24.0- 27.9 kg/m(2): adjusted OR=1.696, 95% CI: 1.426- 2.018; p-BMI≥28.0 kg/m(2): adjusted OR=2.393, 95% CI: 1.831- 3.127), gestational weight gain (GWG) ≥15.9 kg (adjusted OR=2.462, 95% CI: 2.125- 2.853), gravidity>1 (adjusted OR=1.408, 95% CI: 1.224- 1.620), gestational weeks≥40 (adjusted OR=2.007, 95%CI: 1.745-2.308) and gestational diabetes mellitus (adjusted OR=1.522, 95%CI: 1.298-1.784). GWG≥15.9 kg, p-BMI≥28.0 kg/m(2) and gestational weeks≥40 were three risk factors that had the strongest associations with macrosomia (all Pmacrosomia in hospitals with different levels is obvious different. Gestational weeks, p-BMI and GWG are three main controllable risk factors for macrosomia, thus should receive more attentions.

  5. Attenuation of ductus arteriosus intimal thickening in preterm sheep twins compared with singletons.

    Science.gov (United States)

    Ito, Satoko; Yokoyama, Utako; Saito, Junichi; Sato, Shinichi; Usuda, Haruo; Watanabe, Shimpei; Kitanishi, Ryuta; Miura, Yuichiro; Saito, Masatoshi; Hanita, Takushi; Matsuda, Tadashi; Ishikawa, Yoshihiro

    2017-11-01

    Preterm twins have a higher morbidity rate of patent ductus arteriosus (PDA) than do singletons. However, the effect of multiple births on maturation of the ductus arteriosus (DA) has not been reported. Because intimal thickening (IT) is required for DA anatomical closure, we examined IT development in the DA of preterm twins and singletons. Sheep DA tissues obtained from preterm fetuses were subjected to elastica van Gieson staining to evaluate IT. The total IT score in each DA was the sum of the IT scores obtained from six evenly divided parts of the DA, which was positively correlated with gestational ages in singletons. Total IT scores were smaller in preterm twins than in singletons, although no difference in gestational age, birth weight, or gender ratio was observed. These data suggest that IT development of the DA is attenuated in sheep preterm twins, which may affect the higher morbidity of PDA.

  6. Lower perinatal mortality in preterm born twins than in singletons: a nationwide study from The Netherlands.

    Science.gov (United States)

    Vasak, Blanka; Verhagen, Jessica J; Koenen, Steven V; Koster, Maria P H; de Reu, Paul A O M; Franx, Arie; Nijhuis, Jan G; Bonsel, Gouke J; Visser, Gerard H A

    2017-02-01

    Twin pregnancies are at increased risk for perinatal morbidity and death because of many factors that include a high incidence of preterm delivery. Compared with singleton pregnancies, overall perinatal risk of death is higher in twin pregnancies; however, for the preterm period, the perinatal mortality rate has been reported to be lower in twins. The purpose of this study was to compare perinatal mortality rates in relation to gestational age at birth between singleton and twin pregnancies, taking into account socioeconomic status, fetal sex, and parity. We studied perinatal mortality rates according to gestational age at birth in 1,502,120 singletons pregnancies and 51,658 twin pregnancies without congenital malformations who were delivered between 2002 and 2010 after 28 weeks of gestation. Data were collected from the nationwide Netherlands Perinatal Registry. Overall the perinatal mortality rate in twin pregnancies (6.6/1000 infants) was higher than in singleton pregnancies (4.1/1000 infants). However, in the preterm period, the perinatal mortality rate in twin pregnancies was substantially lower than in singleton pregnancies (10.4 per 1000 infants as compared with 34.5 per 1000 infants, respectively) for infants who were born at <37 weeks of gestation; this held especially for antepartum deaths. After 39 weeks of gestation, the perinatal mortality rate was higher in twin pregnancies. Differences in parity, fetal sex, and socioeconomic status did not explain the observed differences in outcome. Overall the perinatal mortality rate was higher in twin pregnancies than in singleton pregnancies, which is most likely caused by the high preterm birth rate in twins and not by a higher mortality rate for gestation, apart from term pregnancies. During the preterm period, the antepartum mortality rate was much lower in twin pregnancies than in singleton pregnancies. We suggest that this might be partially due to a closer monitoring of twin pregnancies, which indirectly

  7. Large baby syndrome in singletons born after frozen embryo transfer (FET)

    DEFF Research Database (Denmark)

    Pinborg, Anja; Henningsen, AA; Loft, A

    2013-01-01

    Are singletons born after frozen embryo transfer (FET) at increased risk of being born large for gestational age (LGA) and if so, is this caused by intrinsic maternal factors or related to the freezing/thawing procedures?......Are singletons born after frozen embryo transfer (FET) at increased risk of being born large for gestational age (LGA) and if so, is this caused by intrinsic maternal factors or related to the freezing/thawing procedures?...

  8. Academic achievement of twins and singletons in early adulthood: Taiwanese cohort study.

    Science.gov (United States)

    Tsou, Meng-Ting; Tsou, Meng-Wen; Wu, Ming-Ping; Liu, Jin-Tan

    2008-07-21

    To examine the long term effects of low birth weight on academic achievements in twins and singletons and to determine whether the academic achievement of twins in early adulthood is inferior to that of singletons. Cohort study. Taiwanese nationwide register of academic outcome. A cohort of 218 972 singletons and 1687 twins born in Taiwan, 1983-5. College attendance and test scores in the college joint entrance examinations. After adjustment for birth weight, gestational age, birth order, and sex and the sociodemographic characteristics of the parents, twins were found to have significantly lower mean test scores than singletons in Chinese, mathematics, and natural science, as well as a 2.2% lower probability of attending college. Low birthweight twins had an 8.5% lower probability of college attendance than normal weight twins, while low birthweight singletons had only a 3.2% lower probability. The negative effects of low birth weight on the test scores in English and mathematics were substantially greater for twins than for singletons. The twin pair analysis showed that the association between birth weight and academic achievement scores, which existed for opposite sex twin pairs, was not discernible for same sex twin pairs, indicating that birth weight might partly reflect other underlying genetic variations. These data support the proposition that twins perform less well academically than singletons. Low birth weight has a negative association with subsequent academic achievement in early adulthood, with the effect being stronger for twins than for singletons. The association between birth weight and academic performance might be partly attributable to genetic factors.

  9. Conformity expectations: Differential effects on IVF twins and singletons' parent-child relationships and adjustment.

    Science.gov (United States)

    Anderson, Kayla N; Rueter, Martha A; Connor, Jennifer J; Chen, Muzi; Damario, Mark

    2015-08-01

    Increased utilization of in vitro fertilization (IVF) to treat infertility has resulted in a growing twin birthrate. Despite early childhood risks, twins have fewer psychosocial problems in middle childhood than singleton children. This study proposes that parents' conformity expectations for children have differential effects on parent-child relationships for twin and singleton children, which indirectly explains twins' more optimum psychosocial adjustment. Parental conformity expectations, parent-child relationship satisfaction, and children's emotional, behavioral, and attention problems were assessed in a sample of 288 6- to 12-year-old IVF-conceived twins and singletons. Overall, parents of twins had higher expectations for child conformity to parent rules than singleton parents. Path models demonstrate that twin status and parental expectations for child conformity interact to influence parent-child relationships, and this interaction indirectly accounted for differences in twins' and singletons' psychosocial adjustment. Findings suggest parenting constructs have differential influences on the association between twin status and parent-child relationships. Parenting research, predominantly conducted with singletons, should be reexamined before applying existing research to twin children and their families. (c) 2015 APA, all rights reserved).

  10. Twin versus singleton pregnancies: the incidence, pregnancy complications, and obstetric outcomes in a Nigerian tertiary hospital.

    Science.gov (United States)

    Obiechina, Nj; Okolie, Ve; Eleje, Gu; Okechukwu, Zc; Anemeje, Oa

    2011-01-01

    Twin pregnancy is associated with more pregnancy complications and poorer pregnancy outcome than singleton pregnancy. Hence periodic review is necessary to improve on the pregnancy outcome. To determine the incidence and compare pregnancy complications and obstetric outcomes of twin pregnancies and singleton pregnancies. The twin pregnancies (study group) that were delivered at Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, South-East Nigeria from 1st February 2005 to 31st January 2010 were compared with singleton deliveries (control group) that occurred in the same hospital during the same period. A total of 3351 deliveries were conducted during the study period, of which 113 were twin deliveries, giving an incidence of 1:29.6 deliveries. Only 100 case files could be retrieved for analysis. The mean parities for the twins and singletons were 2.7 ± 2.33 weeks and 1.96 ± 1.87 weeks whereas the mean gestational age at delivery for twin and singleton deliveries were 34 ± 5.2 weeks and 38.7 ± 2.4 weeks respectively (P < 0.05). The mean birth weights were 3.14 ± 0.73 kg and 2.3 ± 1.0 kg for singletons and twins respectively (P < 0.05). Hypertensive disorders of pregnancy, cord prolapse, malpresentation, premature rupture of membranes, low Apgar scores, cesarean section rate, and perinatal death were significantly higher in twin pregnancies than in singleton. The incidence of twin pregnancy over the study period was high and was significantly associated with more pregnancy complications and poorer obstetric outcomes. Close antenatal and intrapartum care are needed in order to improve outcome and decrease complications.

  11. Physical examination-indicated cerclage in singleton and twin pregnancies: maternal-fetal outcomes.

    Science.gov (United States)

    Bernabeu, Andrea; Goya, Maria; Martra, Miquel; Suy, Anna; Pratcorona, Laia; Merced, Carme; Llurba, Elisa; Casellas, Manel; Carreras, Elena; Cabero, Luis

    2016-01-01

    To study maternal and perinatal outcomes after physical examination-indicated cerclage in both singleton and twin pregnancies and evaluate the possible risk factors associated. Retrospective review of all women undergoing physical examination-indicated cerclage at the Hospital Vall d'Hebro, Barcelona from January 2009 to December 2012 after being diagnosed with cervical incompetence and risk of premature birth. During the study period, 60 cases of women diagnosed with cervical incompetence who were carrying live and morphologically-normal fetuses (53 singleton and 7 twin pregnancies), and who had an imminent risk of premature birth were evaluated. Mean gestational age until birth was 35 weeks in singleton and 32 weeks in twin pregnancies. Four cases (7.5%) of immature births and one case (2.0%) of neonatal death were recorded in singleton pregnancies. No cases of immature births or neonatal deaths were recorded in twin pregnancies. Diagnostic amniocentesis was performed IN all cases to rule out possible chorioamnionitis. Physical examination-indicated cerclage for cervical incompetence in women at risk for immature or preterm birth demonstrates good perinatal prognosis without increasing maternal morbidity in either singleton or twin pregnancies. The increase in gestation time in our study may also have been due to the fact that patients with subclinical chorioamnionitis were excluded by diagnostic amniocentesis.

  12. Prevention of Preterm Birth with Pessary in Singletons (PoPPS): a randomized controlled trial.

    Science.gov (United States)

    Dugoff, Lorraine; Berghella, Vincenzo; Sehdev, Harish; Mackeen, A Dhanya; Goetzl, Laura; Ludmir, Jack

    2017-09-20

    To determine if pessary use prevents preterm birth in singleton gestations with a short transvaginal ultrasound cervical length and without a prior spontaneous preterm birth. In this open-label multicenter randomized trial we enrolled asymptomatic women with singleton gestations with a transvaginal ultrasound cervical length ≤ 25 mm at 18 0 -23 6 weeks and no prior spontaneous preterm birth. Subjects were randomized to receive the Bioteque cup pessary or no pessary. Pessaries were inserted by trained maternal fetal medicine staff.. Vaginal progesterone was recommended to women with a cervical length ≤20mm. The primary outcome was preterm birth preterm birth preterm birth preterm birth preterm birth in women with singleton gestations with a short transvaginal ultrasound cervical length and without a prior spontaneous preterm birth in this small underpowered randomized controlled trial. This trial was registered on ClinicalTrials.gov, number NCT 02056652. This article is protected by copyright. All rights reserved.

  13. Risk of Metabolic Syndrome and Diabetes Mellitus Among Young Twins and Singletons in Guinea-Bissau

    DEFF Research Database (Denmark)

    Bjerregaard-Andersen, Morten; Hansen, Lone; da Silva, Leontina I

    2013-01-01

    OBJECTIVETwins in Africa may be at increased risk of metabolic disorders due to strained conditions in utero, including high exposure to infections. We studied metabolic syndrome (MS) and diabetes mellitus (DM) among young twins and singletons in Guinea-Bissau.RESEARCH DESIGN AND METHODSThe study...... was cross-sectional and occurred from October 2009 until August 2011 at the Bandim Health Project, a demographic surveillance site in the capital Bissau. Twins and singleton controls between 5 and 32 years were visited at home. Fasting blood samples for metabolic measurements were collected. Zygosity...... was established genetically for a subset. DM was defined as HbA1c ≥6.5% (48 mmol/mol) and MS by the International Diabetes Federation criteria.RESULTSHbA1c was available for 574 twins and 463 singletons. Mean age was 15.3 years versus 15.8 years, respectively. Eighteen percent of twins were monozygotic...

  14. Healthcare expenses associated with multiple vs singleton pregnancies in the United States.

    Science.gov (United States)

    Lemos, Elkin V; Zhang, Dongmu; Van Voorhis, Bradley J; Hu, X Henry

    2013-12-01

    The purpose of this study was to document cost that is associated with multiple births vs singleton births in the United States. This was a retrospective cohort study that used a claims database. Women 19-45 years old with live-born infants from 2005-2010 were identified. Infant deliveries were identified by International Classification of Diseases, 9th Revision, Clinical Modification diagnosis codes. The cost entailed all payment made by insurers and patients. For mothers, the cost included expenses from 27 weeks before delivery to 1 month after delivery. For infants, the cost contained all expenses until their first birthday. Adjusted cost was estimated by generalized linear models after adjustment for the potential confounding variables with a gamma distribution and a log link. The analysis included 437,924 eligible deliveries. Of them, 97.02% were singletons; 2.85% were twins, and 0.13% was triplets or more. Women with multiple pregnancies had higher systemic and localized comorbidities compared with women with singleton pregnancies (P < .0001). Twins and triplets or more were more likely to have stayed in a neonatal intensive care unit than were singletons (P < .0001). On average, adjusted total all-cause health care cost was $21,458 (95% confidence interval [CI], $21,302-21,614) per delivery with singletons, $104,831 (95% CI, $103,402-106,280) with twins, and $407,199 (95% CI, $384,984-430,695) with triplets or more. Pregnancies with the delivery of twins cost approximately 5 times as much when compared with singleton pregnancies; pregnancies with delivery of triplets or more cost nearly 20 times as much. Copyright © 2013 Mosby, Inc. All rights reserved.

  15. Assisted Reproductive Technology and Newborn Size in Singletons Resulting from Fresh and Cryopreserved Embryos Transfer.

    Directory of Open Access Journals (Sweden)

    Galit Levi Dunietz

    Full Text Available The aim of this study was two-fold: to investigate the association of Assisted Reproductive Technology (ART and small newborn size, using standardized measures; and to examine within strata of fresh and cryopreserved embryos transfer, whether this association is influenced by parental infertility diagnoses. We used a population-based retrospective cohort from Michigan (2000-2009, Florida and Massachusetts (2000-2010. Our sample included 28,946 ART singletons conceived with non-donor oocytes and 4,263,846 non-ART singletons.Regression models were used to examine the association of ART and newborn size, measured as small for gestational age (SGA and birth-weight-z-score, among four mutually exclusive infertility groups: female infertility only, male infertility only, combined female and male infertility, and unexplained infertility, stratified by fresh and cryopreserved embryos transfer.We found increased SGA odds among ART singletons from fresh embryos transfer compared with non-ART singletons, with little difference by infertility source [adjusted odds-ratio for SGA among female infertility only: 1.18 (95% CI 1.10, 1.26, male infertility only: 1.20 (95% CI 1.10, 1.32, male and female infertility: 1.18 (95% CI 1.06, 1.31 and unexplained infertility: 1.24 (95% CI 1.10, 1.38]. Conversely, ART singletons, born following cryopreserved embryos transfer, had lower SGA odds compared with non-ART singletons, with mild variation by infertility source [adjusted odds-ratio for SGA among female infertility only: 0.56 (95% CI 0.45, 0.71, male infertility only: 0.64 (95% CI 0.47, 0.86, male and female infertility: 0.52 (95% CI 0.36, 0.77 and unexplained infertility: 0.71 (95% CI 0.47, 1.06]. Birth-weight-z-score was significantly lower for ART singletons born following fresh embryos transfer than non-ART singletons, regardless of infertility diagnoses.

  16. Lower marriage and divorce rates among twins than among singletons in Danish birth cohorts 1940-1964

    DEFF Research Database (Denmark)

    Petersen, Inge; Martinussen, Torben; McGue, Matthew

    2011-01-01

    compare rates of marriage and divorce in a sample of 35,975 twins and 81,803 singletons born 1940-1964. Cox-regressions are used in order to control for potential confounders. We find that compared with singletons twins have significantly lower marriage rates: (males: 15-19 years: Hazard Ratio (HR) = 0...... twins compared with singletons (HR=0.87, 95%CI: 0.83-0.90). These differences offset each other, thus 57% of both populations remain in their first marriage until censoring. The interpretation may be that since twins have a partner from birth, they do not have the same need for marriage as singletons...

  17. Why do singletons conceived after assisted reproduction technology have adverse perinatal outcome?

    DEFF Research Database (Denmark)

    Pinborg, A; Wennerholm, U B; Romundstad, L B

    2013-01-01

    Assisted reproduction technology (ART) is used worldwide, at increasing rates, and data show that some adverse outcomes occur more frequently than following spontaneous conception (SC). Possible explanatory factors for the well-known adverse perinatal outcome in ART singletons were evaluated....

  18. Ambulatory arterial stiffness index is unchanged in uncomplicated third-trimester singleton and twin pregnancies.

    Science.gov (United States)

    Kärkkäinen, Henna; Heiskanen, Nonna; Saarelainen, Heli; Valtonen, Pirjo; Lyyra-Laitinen, Tiina; Laitinen, Tomi; Vanninen, Esko; Heinonen, Seppo

    2011-05-01

    To document the ambulatory arterial stiffness index (AASI) during pregnancy compared to three months after delivery in singleton and twin pregnancies. Descriptive study with a follow-up design. University hospital in Eastern Finland. 43 childbearing women; 32 with singleton and 11 with twin pregnancies. Ambulatory blood pressure measurements were conducted using a digital ambulatory blood pressure system. AASI was calculated as 1 minus the regression slope of diastolic on systolic blood pressures obtained from 24-hour monitoring. Arterial stiffness measured by AASI. In normotensive pregnant women, the 95th percentiles of AASI were 0.40 in singleton and 0.46 in twin pregnancies, respectively, implying arterial normality and high elasticity. There were no differences in AASI values between singleton and twin pregnancies and no changes were observed postpartum. After delivery, but not during pregnancy, AASI correlated negatively with nocturnal systolic and diastolic blood pressure reduction (dipping) (r=-0.536, p=0.001; r=-0.674, ptwin pregnancies had no detectable effects on AASI. However, pregnancy appeared to overcome the negative effects of low high-density lipoproteins, unfavorable dipping status and advanced maternal age on arterial stiffness, but not the effect caused by maternal body mass index. © 2011 The Authors Acta Obstetricia et Gynecologica Scandinavica© 2011 Nordic Federation of Societies of Obstetrics and Gynecology.

  19. Trends in preterm birth in singleton deliveries in a Hong Kong population

    NARCIS (Netherlands)

    Hui, Annie S. Y.; Lao, Terence T.; Leung, Tak Yeung; Schaaf, Jelle M.; Sahota, Daljit S.

    2014-01-01

    To examine trends in preterm birth and its relationship with perinatal mortality in Hong Kong. In a retrospective cohort study, data were reviewed from singletons delivered between 1995 and 2011 at a university teaching hospital. Trends in preterm birth (between 24 and 36 weeks of pregnancy),

  20. Body size in five-year-old twins: Heritability and comparison to singleton standards

    NARCIS (Netherlands)

    Estourgie-van Burk, G.F.; Bartels, M.; van Beijsterveldt, C.E.M.; Delemarre-van de Waal, H.A.; Boomsma, D.I.

    2006-01-01

    The aim of this study is to examine causes of individual differences in height, weight and body mass index (BMI) in 5-year-old children registered with the Netherlands Twin Register. In addition, we examine whether the results of twin studies can be expanded to the singleton population by comparing

  1. Comparison of Late Mortality Among Twins Versus Singletons With Congenital Heart Defects

    DEFF Research Database (Denmark)

    Herskind, Anne Maria; Larsen, Lisbeth Aagaard; Pedersen, Dorthe Almind

    2017-01-01

    In 2014, in the United States, nearly 7% of newborns were twins. Congenital heart defects (CHDs) are more frequent in both monozygotic and dizygotic twins than in singletons. Still, the longer-term prognosis for CHD twins is unknown. Here we assess the mortality pattern for CHD twins up to age 36...... years and compare it with that for non-CHD twins, non-CHD co-twins, and CHD singletons. We identified all twins and a 5% random sample of all singletons born in Denmark from 1977 to 2009 by linking Danish national population and health registers. CHD cases were defined as subjects having a primary...... inpatient diagnosis of CHD (excluding preterm ductus) within the first year of life, and mortality was assessed through 2013. Among 63,362 live-born twin individuals, a total of 373 twins (0.59%) had a CHD diagnosis, whereas the corresponding numbers for singletons were 383 of 98,647 (0.39%). During...

  2. Systematic review of progesterone for the prevention of preterm birth in singleton pregnancies

    DEFF Research Database (Denmark)

    Rode, Line; Langhoff-Roos, Jens; Andersson, Charlotte

    2009-01-01

    BACKGROUND: A Cochrane review in 2006 concluded that further knowledge is required before recommendation can be made with regard to progesterone in the prevention of preterm birth. OBJECTIVE: To provide an update on the preventive effect of progesterone on preterm birth in singleton pregnancies. ...

  3. Trends in preterm birth: singleton and multiple pregnancies in the Netherlands, 2000-2007

    NARCIS (Netherlands)

    Schaaf, J. M.; Mol, B. W. J.; Abu-Hanna, A.; Ravelli, A. C. J.

    2011-01-01

    Several studies have reported increasing trends in preterm birth in developed countries, mainly attributable to an increase in medically indicated preterm births. Our aim was to describe trends in preterm birth among singleton and multiple pregnancies in the Netherlands. Prospective cohort study.

  4. Development and health of 5 - 8-year-old singletons born after intracytoplasmic sperm injection

    NARCIS (Netherlands)

    Knoester, Marjolein

    2007-01-01

    This thesis describes the Leiden Artificial Reproductive Techniques Follow-up Project. In this project, the potential long-term effects of intracytoplasmic sperm injection (ICSI) were assessed in 5 – 8-year-old singleton children. ICSI is the method of artificial reproduction in which a sperm cel is

  5. Stillbirth rates in singleton pregnancies in a stable population at Karl ...

    African Journals Online (AJOL)

    To determine the changes in stillbirth rates in singleton pregnancies in a stable population over a period of 50 years. Methods. Stillbirth rates for ... stillbirths, neonatal deaths and deliveries, from which the stillbirth rates for fetuses ≥500 g ... from black residential areas have recently increased rapidly, the study was limited to ...

  6. Trends in birth asphyxia, obstetric interventions and perinatal mortality among term singletons: a nationwide cohort study

    NARCIS (Netherlands)

    Ensing, Sabine; Abu-Hanna, Ameen; Schaaf, Jelle M.; Mol, Ben Willem J.; Ravelli, Anita C. J.

    2015-01-01

    The objective of the present study is to investigate trends in birth asphyxia and perinatal mortality in the Netherlands over the last decade. A nationwide cohort study among women with a term singleton pregnancy. We assessed trends in birth asphyxia in relation to obstetric interventions for fetal

  7. Preterm birth in singleton and multiple pregnancies : evaluation of costs and perinatal outcomes

    NARCIS (Netherlands)

    van Baaren, Gert J.; Peelen, Myrthe J. C. S.; Schuit, Ewoud; van der Post, Joris A. M.; Mol, Ben W. J.; Kok, Marjolein; Hajenius, Petra J.

    Objective: To estimate costs of preterm birth in singleton and multiple pregnancies. Study design: Cost analysis based on data from a prospective cohort study and three multicentre randomised controlled trials (2006-2012) in a Dutch nationwide consortium for women's health research. Women with

  8. Do very preterm twins and singletons differ in their neurodevelopment at 5 years of age?

    Science.gov (United States)

    Bodeau-Livinec, Florence; Zeitlin, Jennifer; Blondel, Béatrice; Arnaud, Catherine; Fresson, Jeanne; Burguet, Antoine; Subtil, Damien; Marret, Stéphane; Rozé, Jean-Christophe; Marchand-Martin, Laetitia; Ancel, Pierre-Yves; Kaminski, Monique

    2013-11-01

    Twins have inconsistently shown poorer outcomes than singletons. Although a high proportion of twins are born very preterm, data are sparse on the long-term outcomes in very preterm twins. The objective of this study was to compare mortality and neurodevelopmental outcomes of very preterm singletons and twins and to study outcomes in relation to factors specific to twins. Birth cohort study Etude Epidemiologique sur les Petits Ages Gestationnels (EPIPAGE). Nine regions in France. All very preterm live births occurring from 22 to 32 weeks of gestation in all maternity wards of nine French regions in 1997 (n=2773). Neurodevelopmental status, including cerebral palsy, and a cognitive assessment with the Kaufman Assessment Battery for Children, with scores on the Mental Processing Composite (MPC) scale, was available for 1732 and 1473 children at 5 years of age, respectively. Among live births, twins had higher hospital mortality than singletons (adjusted (a)OR: 1.4 (95% CI 1.1 to 1.9)). Among survivors, there was no crude difference at 5 years between twins and singletons in the prevalence of cerebral palsy (8.0% vs 9.1%, respectively), MPC <70 (9.5% vs 11.1%) and mean MPC (94.6 vs 94.4). However, after adjustment for sex, gestational age, intrauterine growth restriction and social factors, twins were more likely to have lower MPC scores (mean difference: -2.4 (95% CI-4.8 to 0.01)). Live born twins had a higher risk of mortality when birth weight discordance was present (aOR:2.9 (95% CI 1.7 to 4.8)), but there were no differences in long-term outcomes. Compared with very preterm singletons, twins had higher mortality, no difference with respect to severe deficiencies, but slightly lower MPC scores at 5 years.

  9. Gestational diabetes mellitus: glycemic control during pregnancy and neonatal outcomes of twin and singleton pregnancies.

    Science.gov (United States)

    Guillén-Sacoto, María Augusta; Barquiel, Beatriz; Hillman, Natalia; Burgos, María Ángeles; Herranz, Lucrecia

    2018-04-20

    To assess the impact of glycemic control in gestational on neonatal weight and metabolic complications of twin and singleton pregnancies. An observational, retrospective study to monitor 120 twin and 240 singleton pregnancies in women with GDM. Maternal glycemic parameters during pregnancy (oral glucose tolerance test results, treatment, insulinization rate, mean HbA1c in the third trimester), and neonatal complications and weight were recorded. A higher infant birth weight ratio (IBWR 1.02±0.12 vs. 0.88±0.12, P<.001) and a lower rate of newborns small for gestational age (severe SGA 2.5% vs. 8.3%, P=.012) were seen after singleton pregnancies as compared to twin pregnancies. The rates of newborns large for gestational age (LGA 12.6% vs. 12.5%, P=.989); macrosomic (6.7% vs. 7.5%, P=.777); or small for gestational age (SGA 6.7% vs. 10.8%, P=.175) were similar in both groups. Neonates from twin pregnancies had a higher risk of hypoglycemia (adjusted OR 4.71; 1.38-16.07, P=.013) and polycythemia (adjusted OR 10.05; 1.82-55.42, P=0.008). A linear relationship was seen between third trimester HbA1c levels and IBWR in singleton (r=.199, P=.003), but not in twin pregnancies (r=0.049, P=0.610). Risk of severe SGA, hypoglycemia, and polycythemia was significantly higher in twin pregnancies of women with GDM. Neonatal weight outcomes and metabolic complications in twin pregnancies of women with GDM were not related to glycemic control. Moreover, in our study population, fasting glucose at diagnosis and mean HbA1c in the third trimester showed a linear relationship with higher birth weights in singleton, but not in twin pregnancies. Copyright © 2018 SEEN y SED. Publicado por Elsevier España, S.L.U. All rights reserved.

  10. Placenta previa and risk of major congenital malformations among singleton births in Finland.

    Science.gov (United States)

    Kancherla, Vijaya; Räisänen, Sari; Gissler, Mika; Kramer, Michael R; Heinonen, Seppo

    2015-06-01

    Placenta previa has been associated with adverse birth outcomes, but its association with congenital malformations is inconclusive. We examined the association between placenta previa and major congenital malformations among singleton births in Finland. We performed a retrospective population register-based study on all singletons born at or after 22+0 weeks of gestation in Finland during 2000 to 2010. We linked three national health registers: the Finnish Medical Birth Register, the Hospital Discharge Register, and the Register of Congenital Malformations, and examined several demographic and clinical characteristics among women with and without placenta previa, in association with major congenital malformations. We estimated adjusted odds ratios and 95% confidence intervals using multivariable logistic regression models. The prevalence of placenta previa was estimated as 2.65 per 1000 singleton births in Finland (95% confidence interval, 2.53-2.79). Overall, 6.2% of women with placenta previa delivered a singleton infant with a major congenital malformation, compared with 3.8% of unaffected women (p ≤ 0.001). Placenta previa was positively associated with almost 1.6-fold increased risk of major congenital malformations in the offspring, after controlling for maternal age, parity, fetal sex, smoking, socio-economic status, chorionic villus biopsy, In vitro fertilization, pre-existing diabetes, depression, preeclampsia, and prior caesarean section (adjusted odds ratio = 1.55; 95% confidence interval, 1.27-1.90). Using a large population-based study, we found that placenta previa was weakly, but significantly associated with an increased risk of major congenital malformations in singleton births. Future studies should examine the association between placenta previa and individual types of congenital malformations, specifically in high-risk pregnancies. © 2015 Wiley Periodicals, Inc.

  11. Twin-singleton differences in intelligence: a register-based birth cohort study of Norwegian males.

    Science.gov (United States)

    Eriksen, Willy; Sundet, Jon M; Tambs, Kristian

    2012-10-01

    The aim was to determine the difference in intelligence between singletons and twins in young adulthood. Data from the Medical Birth Register of Norway were linked with register data from the Norwegian National Conscript Service. The study base consisted of data on the 445,463 males who were born alive in either single or twin births in Norway during 1967-1984 and who were examined at the time of the mandatory military conscription (age 18-20). Within this study base, there were data on 1,653 sibships of full brothers that included at least one man born in single birth and at least one man born in twin birth (4,307 persons, including 2,378 twins and 1,929 singletons). The intelligence scores of the singletons were 11% (95% confidence interval [CI]: 9-14%) of a standard deviation higher than those of the twins, after adjustment for birth year, birth order, parental ages at delivery, parental education levels, and other factors. The adjusted within-family difference was also 11% (95 % CI: 6-16%) of a standard deviation, indicating that unmeasured factors shared by siblings (e.g., maternal body height) have not influenced the estimate in important ways. When gestational age at birth was added to the model, the estimate for the difference in intelligence score was approximately the same. Including birth weight in the model strongly reduced the estimate. In conclusion, twins born in Norway during 1967-1984 had slightly lower intelligence in early adulthood compared with the singletons.

  12. Maternal risk factors for singleton preterm births and survival at the ...

    African Journals Online (AJOL)

    2015-02-24

    Feb 24, 2015 ... ratio [aOR] = 2.63; 95% confidence interval [CI] 1.92, 6.07), Previous preterm birth (aOR = 5.06; 95% CI: 2.66, 9.12), ... on gestational age at birth and mode of delivery, but not on maternal sociodemographic risk factors for singleton preterm births. ... of preterms in this area have become important in order to.

  13. Conformal Maxwell Theory as a Singleton Field Theory on $ADS_{5}$, IIB Three Branes and Duality

    CERN Document Server

    Ferrara, Sergio

    1998-01-01

    We examine the boundary conditions associated with extended supersymmetric Maxwell theory in 5-dimensional anti-De Sitter space. Excitations on the boundary are identical to those of ordinary 4-dimensional conformal invariant super electrodynammics. Extrapolations of these excitations give rise to a 5-dimensional topological gauge theory of the singleton type. The possibility of a connection of this phenomenon to the world volume theory of 3-branes in IIB string theory is discussed.

  14. Hierarchical singleton-type recurrent neural fuzzy networks for noisy speech recognition.

    Science.gov (United States)

    Juang, Chia-Feng; Chiou, Chyi-Tian; Lai, Chun-Lung

    2007-05-01

    This paper proposes noisy speech recognition using hierarchical singleton-type recurrent neural fuzzy networks (HSRNFNs). The proposed HSRNFN is a hierarchical connection of two singleton-type recurrent neural fuzzy networks (SRNFNs), where one is used for noise filtering and the other for recognition. The SRNFN is constructed by recurrent fuzzy if-then rules with fuzzy singletons in the consequences, and their recurrent properties make them suitable for processing speech patterns with temporal characteristics. In n words recognition, n SRNFNs are created for modeling n words, where each SRNFN receives the current frame feature and predicts the next one of its modeling word. The prediction error of each SRNFN is used as recognition criterion. In filtering, one SRNFN is created, and each SRNFN recognizer is connected to the same SRNFN filter, which filters noisy speech patterns in the feature domain before feeding them to the SRNFN recognizer. Experiments with Mandarin word recognition under different types of noise are performed. Other recognizers, including multilayer perceptron (MLP), time-delay neural networks (TDNNs), and hidden Markov models (HMMs), are also tested and compared. These experiments and comparisons demonstrate good results with HSRNFN for noisy speech recognition tasks.

  15. The Singleton case: enforcing medical treatment to put a person to death.

    Science.gov (United States)

    Garasic, Mirko Daniel

    2013-11-01

    In October 2003 the Supreme Court of the United States allowed Arkansas officials to force Charles Laverne Singleton, a schizophrenic prisoner convicted of murder, to take drugs that would render him sane enough to be executed. On January 6 2004 he was killed by lethal injection, raising many ethical questions. By reference to the Singleton case, this article will analyse in both moral and legal terms the controversial justifications of the enforced medical treatment of death-row inmates. Starting with a description of the Singleton case, I will highlight the prima facie reasons for which this case is problematic and merits attention. Next, I will consider the justification of punishment in Western society and, in that context, the evolution of the notion of insanity in the assessment of criminal responsibility during the past two centuries, both in the US and the UK. In doing so, I will take into account the moral justification used to enforce treatment, looking at the conflict between the prisoner's right to treatment and his right to refuse medication where not justified by outcomes that can be reasonably expected to be positive for the individual. Finally, in contrast with some retributivist arguments in favour of enforced treatment to enable execution, I will propose a possible alternative, necessary if we are to consistently uphold the notion of autonomy.

  16. Birthweight distribution in ART singletons resulting from embryo culture in two different culture media compared with the national population.

    Science.gov (United States)

    Lemmen, J G; Pinborg, A; Rasmussen, S; Ziebe, S

    2014-10-10

    Is there a difference in birthweight distribution in ART singletons born after IVF culture in two different culture media? There is no effect of culture media on both crude and adjusted birthweight distributions in ART singletons from nulliparous mothers. Studies on human ART singletons have reported a difference in birthweight in singletons following IVF culture in different culture media. However, other studies comparing different culture media have not shown any significant differences in birthweight. This study was a retrospective comparison of birthweights in IVF/ICSI singletons conceived after fresh embryo transfer following embryo culture in Cook or Medicult medium and in a national cohort of naturally conceived singletons in nulliparous women. The study compares four independent groups consisting of singletons in nulliparous women from Cook-d2: 2-day culture in Cook medium at Rigshospitalet (n = 974), Medicult-d2: 2-day culture in Medicult EmbryoAssist medium at Rigshospitalet (n = 147), Medicult-d3: 3-day culture in Medicult EmbryoAssist medium with and without added GM-CSF (n = 204), and DK: pregnancies from the Danish birth registry (n = 106842). The study compares the birthweights of singletons from nulliparous women in the four independent groups mentioned above; Cook-d2: Medicult-d2: Medicult-d3: and DK. In addition, distributions of large and small for gestational age infants were compared between the groups and a multiple linear regression analysis was used to determine which factors determined birthweight. We found no significant difference in the crude birthweight distributions between singletons born after culture in Cook-d2 or Medicult-groups. Singleton girls from the Cook-d2 group weighed 3302 ± 28 g, versus 3252 ± 76 in the Medicult-d2 group (difference 50 g; P = 0.547). Singleton boys from the Cook-d2 group weighed 3430 ± 27 g, versus 3354 ± 56 in the Medicult-d2 group (difference 76 g; P = 0.279). In the background population, mean

  17. An unusual case of asymptomatic hyperreactio luteinalis present at cesarean section of a spontaneous singleton pregnancy

    Directory of Open Access Journals (Sweden)

    Ahmed M. Abbas

    2017-06-01

    Full Text Available Hyperreactio Luteinalis (HL is a benign self-limited pregnancy-related condition characterized by bilateral ovarian enlargement with multiple theca lutein cysts. It is commonly associated with gestational trophoblastic diseases and multiple pregnancy. We report a rare case of HL discovered accidentally during cesarean section (CS of a spontaneously conceived normal singleton pregnancy. CS was performed due to fetal malpresentation and previously scarred uterus, and delivered a healthy male neonate. Expectant management was performed to permit conservation of both ovaries without unnecessary surgical intervention. The condition resolved within 6 weeks postpartum without adding morbidity to the patient.

  18. Assisted reproductive technology and the risk of pregnancy-related complications and adverse pregnancy outcomes in singleton pregnancies: a meta-analysis of cohort studies.

    Science.gov (United States)

    Qin, Jiabi; Liu, Xiaoying; Sheng, Xiaoqi; Wang, Hua; Gao, Shiyou

    2016-01-01

    To determine whether there are any increases in pregnancy-related complications and adverse pregnancy outcomes in singleton pregnancies after assisted reproductive technology (ART) compared with those conceived naturally. Meta-analysis. University-affiliated teaching hospital. Singleton pregnancies conceived with ART and naturally. PubMed, Google Scholar, Cochrane Libraries and Chinese database were searched through March 2015 to identify studies that met pre-stated inclusion criteria. Either a fixed- or a random-effects model was used to calculate the overall combined risk estimates. Subgroup analysis was performed to explore potential heterogeneity moderators. Pregnancy-related complications and adverse pregnancy outcomes. Fifty cohort studies comprising 161,370 ART and 2,280,241 spontaneously conceived singleton pregnancies were identified. The ART singleton pregnancies had a significantly increased risk of pregnancy-induced hypertension (relative risk [RR] 1.30, 95% confidence interval [CI] 1.04-1.62; I(2) = 79%), gestational diabetes mellitus (RR 1.31, 95% CI 1.13-1.53; I(2) = 6%), placenta previa (RR 3.71, 95% CI 2.67-5.16; I(2) = 72%), placental abruption (RR 1.83, 95% CI 1.49-2.24; I(2) = 22%), antepartum hemorrhage (RR 2.11, 95% CI 1.86-2.38; I(2) = 47%), postpartum hemorrhage (RR 1.29, 95% CI 1.06-1.57; I(2) = 65%), polyhydramnios (RR 1.74, 95% CI 1.24-2.45; I(2) = 0%), oligohydramnios (RR 2.14, 95% CI 1.53-3.01; I(2) = 0%), cesarean sections (RR 1.58, 95% CI 1.48-1.70; I(2) = 92%), preterm birth (RR 1.71, 95% CI 1.59-1.83; I(2)=80%), very preterm birth (RR 2.12, 95% CI 1.73-2.59; I(2) = 90%), low birth weight (RR 1.61, 95% CI 1.49-1.75; I(2) = 80%), very low birth weight (RR 2.12, 95% CI 1.84-2.43; I(2) = 67%), small for gestational age (RR 1.35, 95% CI 1.20-1.52; I(2) = 82%), perinatal mortality (RR 1.64, 95% CI 1.41-1.90; I(2)=45%), and congenital malformation (RR 1.37, 95% CI 1.29-1.45; I(2)=41%). Relevant heterogeneity moderators have been identified

  19. Umbilical cord length in singleton gestations: a Finnish population-based retrospective register study.

    Science.gov (United States)

    Georgiadis, L; Keski-Nisula, L; Harju, M; Räisänen, S; Georgiadis, S; Hannila, M-L; Heinonen, S

    2014-04-01

    Many complications of pregnancy and delivery are associated with umbilical cord length. It is important to examine the variation in length, in order to identify normal and abnormal conditions. Moreover, the factors influencing cord growth and development are not precisely known. The main objectives were to provide updated reference charts for umbilical cord length in singleton pregnancies and to evaluate potential factors affecting cord length. Birth register data of 47,284 singleton pregnant women delivering in Kuopio University Hospital, Finland was collected prospectively. Gender-specific centile charts for cord length from 22 to 44 gestational weeks were obtained using generalized additive models for location, scale, and shape (GAMLSS). Gestational, fetal, and maternal factors were studied for their potential influence on cord length with single variable analysis and stepwise multiple linear regression analysis. Cord length increased according to gestational age, while the growth decelerated post-term. Birth weight, placental weight, pregravid maternal body mass index, parity, and maternal age correlated to cord length. Gestational diabetes and previous miscarriages were associated with longer cords, while female gender and placental abruption were associated with shorter cords. Girls had shorter cords throughout gestation although there was substantial variation in length in both genders. Cord length associated significantly with birth weight, placental weight, and gestational age. Significantly shorter cords were found in women with placental abruption. This important finding requires further investigation. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Reference charts and equations of fetal biometry for normal singleton pregnant women in Shaanxi, China.

    Science.gov (United States)

    Jiang, X; Zhang, Y H; Li, Y; Ma, X; Zhu, Y S H; Shang, L

    2013-01-01

    To construct reference charts and equations of fetal biometry for singleton pregnant women in Shaanxi, China. This was a cross-sectional study involving 6,832 singleton pregnant women. One set of fetal ultrasonographic measurement data between the 16th to 41st gestational weeks (GW) was randomly selected from each pregnant woman, and biparietal diameter (BPD), abdominal circumference (AC), and femur length (FL) were recorded. Mean and standard deviation (SD) of BPD, AC, and FL were fitted by polynomial. Centile = Mean + Z(alpha) x SD was used to calculate centiles. Differences in the 50th centile of BPD, AC, and FL between Hong Kong, Korean, Italian and Shaanxi fetuses were compared. Mean of BPD, AC, and FL were well-fitted by quadratic polynomial, SD of BPD, AC and FL were fitted by linear regression. Equations for estimating mean and SD for BPD, AC, and FL from GW were obtained. Centiles for BPD,AC, and FL were calculated. From the 21st GW, the differences in BPD,AC, and FL between Hong Kong, Korean, Italian, and Shaanxi fetuses became larger. Fetal biometry reference charts and equations for estimating fetal size and GW could be used in obstetrics practice and research in Shaanxi, China.

  1. First trimester β-hCG and estradiol levels in singleton and twin pregnancies after assisted reproduction.

    Science.gov (United States)

    Póvoa, Ana; Xavier, Pedro; Matias, Alexandra; Blicksttein, Isaac

    2017-07-28

    To compare levels of β-hCG and estradiol collected during the first trimester in singleton and twin pregnancies following assisted reproduction technologies (ART). We prospectively evaluated 50 singleton and 47 dichorionic twin pregnancies that eventually ended in live births. Patients were recruited from a single ART center with standard treatment protocols followed by fresh embryo transfers. Hormone measurements were performed within a narrow gestational age range and analyzed in a single laboratory thus minimizing inter- and intra-assay variability. We measured serum β-hCG at 13 days after embryo transfer as well as samples of β-hCG and estradiol at 8-9 weeks+6 days. No significant differences existed between singletons and twins in respect to demographic and cycle characteristics. β-hCG and estradiol were all significantly higher in twins (PhCG and estradiol in twins, pointing to the potential role of these placental hormones in early support of a twin pregnancy.

  2. Analysis of intracranial hemorrhage grade in preterm singleton pregnancies delivered vaginally or by cesarean section

    Directory of Open Access Journals (Sweden)

    Ljuština Saša

    2013-01-01

    Full Text Available Background/Aim. Preterm birth is the leading cause of neonatal mortality. Periventricular hemorrhage-intraventricular hemorrhage (PVH-IVH remains a significant cause of both morbidity and mortality in infants prematurely born. The aim of the study was to evaluate the perinatal outcome regarding IVH of premature babies according to the mode of delivery. Methods. A total of 126 women in preterm singleton pregnancies with vertex presentation and 126 neonates weighted from 750 g to 1,500 g at birth were enrolled. The outcomes of 64 neonates born vaginally were compared to 62 neonates born by cesarean section. Results. There was no significant difference in the incidence of IVH among both groups. Conclusion. Our data is consistent with the hypothesis that the mode of delivery does not influence IVH and consenquently perinatal outcome in preterm neonates.

  3. Excess Mortality in Patients Diagnosed With Hypothyroidism: A Nationwide Cohort Study of Singletons and Twins

    Science.gov (United States)

    Thvilum, Marianne; Brandt, Frans; Almind, Dorthe; Christensen, Kaare; Brix, Thomas Heiberg

    2013-01-01

    Background: Although hypothyroidism is associated with increased morbidity, an association with increased mortality is still debated. Our objective was to investigate, at a nationwide level, whether a diagnosis of hypothyroidism influences mortality. Methods: In an observational cohort study from January 1, 1978 until December 31, 2008 using record-linkage data from nationwide Danish health registers, 3587 singletons and 682 twins diagnosed with hypothyroidism were identified. Hypothyroid individuals were matched 1:4 with nonhypothyroid controls with respect to age and gender and followed over a mean period of 5.6 years (range 0–30 years). The hazard ratio (HR) for mortality was calculated using Cox regression analyses. Comorbidity was evaluated using the Charlson score (CS). Results: In singletons with hypothyroidism, the mortality risk was increased (HR 1.52; 95% confidence interval [CI]: 1.41–1.65). Although the effect attenuated, hypothyroidism remained associated with increased mortality when evaluating subjects with a CS = 0 (HR 1.23; 95% CI: 1.05–1.44). In twin pairs discordant for hypothyroidism, the hypothyroid twin had excess mortality compared with the corresponding euthyroid cotwin (HR 1.40; 95% CI 0.95–2.05). However, after stratifying for zygosity, hypothyroidism was associated with excess mortality in dizygotic twin pairs (HR 1.61; 95% CI 1.00–2.58), whereas the association attenuated in monozygotic pairs (HR 1.06; 95% CI 0.55–2.05). Conclusions: Hypothyroidism is associated with an excess mortality of around 50%, which to some degree is explained by comorbidity. In addition, the finding of an association between hypothyroidism and mortality within disease discordant dizygotic but not monozygotic twin pairs indicates that the association between hypothyroidism and mortality is also influenced by genetic confounding. PMID:23365121

  4. Modelling and Simulation of Search Engine

    Science.gov (United States)

    Nasution, Mahyuddin K. M.

    2017-01-01

    The best tool currently used to access information is a search engine. Meanwhile, the information space has its own behaviour. Systematically, an information space needs to be familiarized with mathematics so easily we identify the characteristics associated with it. This paper reveal some characteristics of search engine based on a model of document collection, which are then estimated the impact on the feasibility of information. We reveal some of characteristics of search engine on the lemma and theorem about singleton and doubleton, then computes statistically characteristic as simulating the possibility of using search engine. In this case, Google and Yahoo. There are differences in the behaviour of both search engines, although in theory based on the concept of documents collection.

  5. Search Help

    Science.gov (United States)

    Guidance and search help resource listing examples of common queries that can be used in the Google Search Appliance search request, including examples of special characters, or query term seperators that Google Search Appliance recognizes.

  6. A comparison of perinatal outcomes in singletons and multiples born after IVF or ICSI, stratified for neonatal risk criteria

    NARCIS (Netherlands)

    van Heesch, Mirjam M. J.; Evers, Johannes L. H.; Dumoulin, John C. M.; van der Hoeven, Mark A. H. B. M.; van Beijsterveldt, Catharina E. M.; Bonsel, Gouke J.; Dykgraaf, Ramon H. M.; van Goudoever, Johannes B.; Koopman-Esseboom, Corine; Nelen, Willianne L. D. M.; Steiner, Katerina; Tamminga, Pieter; Tonch, Nino; van Zonneveld, Piet; Dirksen, Carmen D.

    2014-01-01

    To compare perinatal singleton and multiple outcomes in a large Dutch in-vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) population and within risk subgroups. Newborns were assigned to a risk category based on gestational age, birthweight, Apgar score and congenital malformation.

  7. Can early ultrasonography explain the lower miscarriage rates in twin as compared to singleton pregnancies following assisted reproduction?

    Science.gov (United States)

    Póvoa, Ana; Matias, Alexandra; Xavier, Pedro; Blickstein, Isaac

    2017-06-20

    To compare first trimester 2D conventional and 3D power Doppler angiography measures in twins and singletons following assisted reproduction. We prospectively evaluated 50 singleton and 47 twin pregnancies that eventually ended in live births. Patients were recruited from a single assisted reproductive technology (ART) center with standard treatment protocols. Obstetric ultrasound was performed at 8-9 weeks +6 days. Intervillous flow, uteroplacental circulation and uterine artery pulsatility (PI) and resistance index (RI) using two-dimensional (2D) ultrasound examination were evaluated. Using three-dimensional (3D) power Doppler angiography, placental volume and the 3D power Doppler indices from the intervillous and uteroplacental circulation were calculated. Demographic and cycle characteristics were similar in mothers of singletons and twins. Placental volume was significantly (1.6-fold) larger in twins. Vascular density and blood perfusion in the intervillous space were lower in twins. The comparison of the other parameters did not show significant differences between singletons and twins. The data confirm the larger placental volume in twins, denoting a probable higher production of placental hormones that would support an early twin pregnancy. The lower vascular density and blood perfusion in the intervillous space in twins may also confer a reproductive advantage to them.

  8. Differences in outcome between twins and singletons born very preterm: results from a population-based European cohort.

    NARCIS (Netherlands)

    Papiernik, E.; Zeitlin, J.; Delmas, D.; Blondel, B.; Kunzel, W.; Cuttini, M.; Weber, T.; Petrou, S.; Gortner, L.; Kollee, L.A.A.; Draper, E.S.

    2010-01-01

    BACKGROUND: About 10% of twins are born before 32 weeks of gestation and very preterm birth rates are increasing. Preterm twins tend to have more favourable outcomes than singletons of the same gestational age, but fewer data are available for very preterm infants. This study aims to determine

  9. Prevalence of impaired glucose tolerance and other types of dysglycaemia among young twins and singletons in Guinea-Bissau

    DEFF Research Database (Denmark)

    Egegaard Hennild, Ditte; Bjerregaard-Andersen, Morten; Joaquím, Luis Carlos

    2016-01-01

    BACKGROUND: Twins may be at increased risk of dysglycaemic disorders due to adverse fetal conditions. Data from Africa regarding this association is limited. We studied impaired glucose tolerance (IGT) and other types of dysglycemia among twins and singletons in Guinea-Bissau. METHODS: The study...

  10. Mid-pregnancy, perinatal, and neonatal reproductive endocrinology: a prospective cohort study in twins and singleton control subjects.

    Science.gov (United States)

    Kuijper, Esther A M; Twisk, Jos W R; Korsen, Ted; Caanen, Mirte R; Kushnir, Mark M; Rockwood, Alan L; Meikle, A Wayne; Hompes, Peter G; Wit, Jan M; Lambalk, Cornelis B

    2015-12-01

    To answer the questions: Are perinatal reproductive hormone profiles different in case of a twin compared with a singleton pregnancy? Are reproductive endocrine profiles of twin girls influenced by their male co-twin and vice versa? Prospective cohort study from January 2004 to October 2009. Not applicable. A total of 204 mothers of twins and 248 singleton control subjects, aged >18 years, pregnant with a twin or singleton and no endocrine disease or malignancy. Blood samples were collected at mid-gestation from the mother and at delivery from the mothers and the umbilical cords. Estrogens, androgens, sex hormone-binding globulin, progesterone, and gonadotropins were measured. Hormonal profiles were compared between singletons and twins, different types of twins, and opposite-sex and same-sex twins. Estrogen and progesterone concentrations were higher in mothers of twins compared with singletons, but twin babies had lower estrogen and progesterone concentrations at birth. Opposite-sex twin girls did not have higher androgens in cord blood compared with same-sex twin girls. Boys of an opposite-sex twin had lower luteinizing hormone concentrations compared with dizygotic twin boys with a brother as a co-twin. Children from a twin are not overexposed to sex steroids at the time of birth, despite higher concentrations in their mothers, and girls from opposite sex twins do not show androgenic influences from their male co-twin. The female co-twin may influence the hypothalamic-pituitary-testicular axis of her brother via central inhibition. Copyright © 2015 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  11. How the cervix shortens: an anatomic study using 3-dimensional transperineal sonography and image registration in singletons and twins.

    Science.gov (United States)

    Parikh, Reshma; Patel, Atur; Stack, Trevor; Socrate, Simona; House, Michael

    2011-09-01

    The purpose of this study was to use a fixed reference to study movement (displacement) of the cervical internal os from the second to the third trimester in singletons and twins. The rationale was to gain insight into anatomic changes associated with cervical shortening. For each patient, 2 transperineal scans were performed 12 weeks apart (20 and 32 weeks). The internal os and symphysis pubis were visualized in the same field of view. Image registration techniques were used to align the 2 scans using the symphysis as a fixed reference. Total displacement, anterior displacement, and inferior displacement of the internal os were measured. Displacements were correlated with cervical shortening. Bland-Altman plots and interobserver intraclass correlation coefficients were calculated. A total of 42 healthy participants were studied: 28 with singletons and 14 with twins. The mean ± SD values for total displacement were 2.1 ± 1.2 and 2.0 ± 1.2 cm for singletons and twins, respectively (P = .75). The direction of displacement was significantly different. The mean anterior displacement was 1.1 cm greater for singletons than for twins (95% confidence interval, 0.29-2.0 cm, P = .01). Mean inferior displacement was 1.3 cm greater for twins than for singletons (95% confidence interval, 2.2-0.1 cm; P = .03). Only inferior displacement correlated with cervical shortening (P < .001; R(2) = 0.74). For every 2.2 cm of inferior displacement, the cervix shortened 1.0 cm. Assessments of reliability showed good agreement between 2 observers. The anatomic position of the internal cervical os depends on gestational age and fetal number. Cervical shortening correlated most strongly with inferior displacement.

  12. Effect of Body Mass Index on pregnancy outcomes in nulliparous women delivering singleton babies

    Directory of Open Access Journals (Sweden)

    Liston William A

    2007-07-01

    Full Text Available Abstract Background The increasing prevalence of obesity in young women is a major public health concern. These trends have a major impact on pregnancy outcomes in these women, which have been documented by several researchers. In a population based cohort study, using routinely collected data, this paper examines the effect of increasing Body Mass Index (BMI on pregnancy outcomes in nulliparous women delivering singleton babies. Methods This was a retrospective cohort study, based on all nulliparous women delivering singleton babies in Aberdeen between 1976 and 2005. Women were categorized into five groups – underweight (BMI 2, normal (BMI 20 – 24.9 Kg/m2 overweight (BMI 25 – 29.9 Kg/m2, obese (BMI 30 – 34.9 Kg/m2 and morbidly obese (BMI > 35 Kg/m2. Obstetric and perinatal outcomes were compared by univariate and multivariate analyses. Results In comparison with women of BMI 20 – 24.9, morbidly obese women faced the highest risk of pre-eclampsia {OR 7.2 (95% CI 4.7, 11.2} and underweight women the lowest {OR 0.6 (95% CI 0.5, 0.7}. Induced labour was highest in the morbidly obese {OR 1.8 (95% CI 1.3, 2.5} and lowest in underweight women {OR 0.8 (95% CI 0.8, 0.9}. Emergency Caesarean section rates were highest in the morbidly obese {OR 2.8 (95% CI 2.0, 3.9}, and comparable in women with normal and low BMI. Obese women were more likely to have postpartum haemorrhage {OR 1.5 (95% CI 1.3, 1.7} and preterm delivery ( 4,000 g was in the morbidly obese {OR 2.1 (95% CI 1.3, 3.2} and the lowest in underweight women {OR 0.5 (95% CI 0.4, 0.6}. Conclusion Increasing BMI is associated with increased incidence of pre-eclampsia, gestational hypertension, macrosomia, induction of labour and caesarean delivery; while underweight women had better pregnancy outcomes than women with normal BMI.

  13. Divergence of estimated fetal weight and birth weight in singleton fetuses.

    Science.gov (United States)

    Sotiriadis, Alexandros; Eleftheriades, Makarios; Papadopoulos, Vassileios; Sarafidis, Kosmas; Pervanidou, Panagiota; Assimakopoulos, Efstratios

    2018-03-01

    To evaluate differences in distribution of estimated fetal weight (EFW) and birth weight (BW) of ongoing fetuses and neonates of the same gestational age. Reference curves for EFW (Hadlock BPD-HC-AC-FL formula, N = 1191) and BW (N = 1036) in singleton pregnancies from 24 +0 to 40 +6 gestational weeks were calculated. Multiple pregnancies, fetuses with major or multiple abnormalities or syndromes and iatrogenic preterm deliveries due to preeclampsia or abnormal fetal Doppler were excluded. The standardized residuals for EFW and BW were calculated and compared. EFW and BW can be accurately described by quadratic equations (R 2  = 0.944 and 0.807, respectively). The distribution of standardized residuals for BW using the EFW formula was negative from 28 +0 to 35 +6 weeks. The 50th and 5th centiles of BW were lower than those of EFW throughout prematurity, and they converged at approximately 38 gestational weeks. The 5th centile for BW was 30% lower than the 5th centile for EFW at 27 weeks, 27.5% lower at 30 weeks and 19.4% at 34 weeks. Preterm infants have lower BW distribution compared to the expected EFW of ongoing pregnancies of the same gestational age, supporting the concept of hidden intrauterine morbidity for a proportion of these infants.

  14. Determinants of successful breastfeeding initiation in healthy term singletons: a Swiss university hospital observational study.

    Science.gov (United States)

    Gubler, Tabea; Krähenmann, Franziska; Roos, Malgorzata; Zimmermann, Roland; Ochsenbein-Kölble, Nicole

    2013-05-01

    Breastfeeding significantly benefits mothers and infants. We aimed to identify the determinants of its successful initiation. A retrospective study of 1893 mothers delivering healthy term singletons at a Swiss university hospital from 1/2008 to 3/2009 determined the associations between multiple breastfeeding and early postpartum parameters by univariate and multiple regression analysis. Multiparity was associated with nursing exclusively at the breast at discharge (Ppacifier use (P<0.05). Among obese mothers, nursing exclusively at the breast at discharge was less frequent, and use of all feeding aids more frequent, than among normal-weight women (both P<0.001). Neuraxial anesthesia was associated with use of maltodextrin and bottle (both P<0.05) compared to no anesthesia. Delayed first skin-to-skin contact and rooming-in for <24 h/day were each associated with maltodextrin and cup (P<0.05). Nursing exclusively at the breast at discharge was less frequent (P<0.001), and bottle use more frequent (P<0.05), in women with sore nipples than in those without. Obesity is a potent inhibitor of breastfeeding initiation. Delivery without anesthesia by a multiparous normal-weight mother, followed by immediate skin-to-skin contact, rooming-in for 24 h/day, and dedicated nipple care, provides the best conditions for successful early postpartum breastfeeding without the need for feeding aids or nutritional supplements

  15. RIG-I-Like Receptor Signaling in Singleton-Merten Syndrome

    Directory of Open Access Journals (Sweden)

    Changming Lu

    2017-09-01

    Full Text Available Singleton-Merten syndrome (SMS is an autosomal dominant, multi-system innate immune disorder characterized by early and severe aortic and valvular calcification, dental and skeletal abnormalities, psoriasis, glaucoma, and other varying clinical findings. Recently we identified a specific gain-of-function mutation in IFIH1, interferon induced with helicase C domain 1, segregated with this disease. SMS disease without hallmark dental anomalies, termed atypical SMS, has recently been reported caused by variants in DDX58, DEXD/H-box helicase 58. IFIH1 and DDX58 encode retinoic acid-inducible gene I (RIG-I-like receptors family members melanoma differentiation-associated gene 5 and RIG-I, respectively. These cytosolic pattern recognition receptors function in viral RNA detection initiating an innate immune response through independent pathways that promote type I and type III interferon expression and proinflammatory cytokines. In this review, we focus on SMS as an innate immune disorder summarizing clinical features, molecular aspects of the pathogenetic pathway and discussing underlying mechanisms of the disease.

  16. [Singleton and twin pregnancies of PKU patients - individual variability of phenylalanine tolerance: experience of a single treatment center (Preliminary report)].

    Science.gov (United States)

    Żółkowska, Joanna; Hozyasz, Kamil K; Nowacka, Maria

    2017-01-01

    Phenylketonuria (PKU) is the autosomal recessive deficiency of phenylalanine hydroxylase resulting in the accumulation of phenylalanine (Phe) in blood and in the brain. Phe restriction in a patient's diet is determined depending on the amount of Phe intake which allows for stable blood Phe levels within the therapeutic range of 120-360µmol/L. In clinical practice the empirical determination of Phe tolerance relies on frequent assessment of blood Phe concentrations in relation to Phe intake from food records. Untreated maternal PKU may lead to maternal PKU syndrome in offspring. The objective of the study was to compare Phe tolerance during the course of singleton and multiple pregnancies of PKU patients. Case subjects and methods: The cases reviewed included three sets of classical PKU-affected Polish women on a low-phenylalanine diet during the course of singleton and twin pregnancies and their PKU-unaffected newborns. All the patients were under regular supervision of a metabolic dietitian to stabilize blood Phe levels and determine Phe tolerance. Data on pregnancy weight gain, the gestational age when the diet initiated, the percent of Phe assessments 360 µmol/L, as well as offspring birth measurements were analyzed. The total increase in Phe tolerance and its pattern during the course of singleton and twin pregnancies differed remarkably in each patient. Three PKU women (Q383X/R408W, EX3DEL/EX3DEL, R281L/R408W) increased their Phe tolerance in singleton and twin pregnancies by 579%/468%, 674%/261%, and 427%/236%, respectively. During the last 10 weeks of singleton and twin pregnancy Phe tolerance showed an increase by 62%/149%, 33%/64%, and 37%/40%, respectively. The analysis of predictors for Phe tolerance showed that an individual's weight gain and the fetal weight gain as estimated from liveborn birth-weight data had no predictive capacity. Individual Phe tolerance in singleton pregnancies of PKU patients does not predict tolerance in twin pregnancy

  17. Attentional Capture by Salient Distractors during Visual Search Is Determined by Temporal Task Demands

    DEFF Research Database (Denmark)

    Kiss, Monika; Grubert, Anna; Petersen, Anders

    2012-01-01

    The question whether attentional capture by salient but taskirrelevant visual stimuli is triggered in a bottom–up fashion or depends on top–down task settings is still unresolved. Strong support for bottom–up capture was obtained in the additional singleton task, in which search arrays were visible...

  18. Mutations in DDX58, which Encodes RIG-I, Cause Atypical Singleton-Merten Syndrome

    Science.gov (United States)

    Jang, Mi-Ae; Kim, Eun Kyoung; Now, Hesung; Nguyen, Nhung T.H.; Kim, Woo-Jong; Yoo, Joo-Yeon; Lee, Jinhyuk; Jeong, Yun-Mi; Kim, Cheol-Hee; Kim, Ok-Hwa; Sohn, Seongsoo; Nam, Seong-Hyeuk; Hong, Yoojin; Lee, Yong Seok; Chang, Sung-A; Jang, Shin Yi; Kim, Jong-Won; Lee, Myung-Shik; Lim, So Young; Sung, Ki-Sun; Park, Ki-Tae; Kim, Byoung Joon; Lee, Joo-Heung; Kim, Duk-Kyung; Kee, Changwon; Ki, Chang-Seok

    2015-01-01

    Singleton-Merten syndrome (SMS) is an autosomal-dominant multi-system disorder characterized by dental dysplasia, aortic calcification, skeletal abnormalities, glaucoma, psoriasis, and other conditions. Despite an apparent autosomal-dominant pattern of inheritance, the genetic background of SMS and information about its phenotypic heterogeneity remain unknown. Recently, we found a family affected by glaucoma, aortic calcification, and skeletal abnormalities. Unlike subjects with classic SMS, affected individuals showed normal dentition, suggesting atypical SMS. To identify genetic causes of the disease, we performed exome sequencing in this family and identified a variant (c.1118A>C [p.Glu373Ala]) of DDX58, whose protein product is also known as RIG-I. Further analysis of DDX58 in 100 individuals with congenital glaucoma identified another variant (c.803G>T [p.Cys268Phe]) in a family who harbored neither dental anomalies nor aortic calcification but who suffered from glaucoma and skeletal abnormalities. Cys268 and Glu373 residues of DDX58 belong to ATP-binding motifs I and II, respectively, and these residues are predicted to be located closer to the ADP and RNA molecules than other nonpathogenic missense variants by protein structure analysis. Functional assays revealed that DDX58 alterations confer constitutive activation and thus lead to increased interferon (IFN) activity and IFN-stimulated gene expression. In addition, when we transduced primary human trabecular meshwork cells with c.803G>T (p.Cys268Phe) and c.1118A>C (p.Glu373Ala) mutants, cytopathic effects and a significant decrease in cell number were observed. Taken together, our results demonstrate that DDX58 mutations cause atypical SMS manifesting with variable expression of glaucoma, aortic calcification, and skeletal abnormalities without dental anomalies. PMID:25620203

  19. Intrapartum and neonatal outcomes in singleton pregnancies following conception by assisted reproduction techniques.

    Science.gov (United States)

    Rozdarz, Kellie M; Flatley, Christopher J; Kumar, Sailesh

    2017-12-01

    To characterise maternal demographics and ascertain whether clinically important differences exist in the intrapartum and neonatal outcomes associated with assisted reproductive technology (ART). A retrospective study was undertaken between January 2007 and December 2013 of all singleton pregnancies conceived via ART at a major tertiary unit in Brisbane, Australia. Intrapartum outcomes were mode of delivery and indication for emergency caesarean. Neonatal outcomes investigated were gestation at delivery, birth weight, Apgar scores, acidosis at birth, respiratory distress, need for resuscitation, admission to neonatal intensive care and stillbirth. There were 4733 (7.4%) ART and 59 277 (92.6%) spontaneous conception pregnancies. Women who conceived using ART were less likely to have a spontaneous vaginal delivery (odds ratio (OR) 0.60, 95% CI 0.57-0.64) and were more likely to require operative or assisted birth: elective caesarean (adjusted OR (aOR) 1.31, 95% CI 1.22-1.40), emergency caesarean (aOR 1.19, 95% CI 1.09-1.28), or instrumental delivery (aOR 1.45, 95% CI 1.32-1.58). Neonates who were conceived using ART were less likely to be born at term (aOR 0.64, 95% CI 0.58-0.71) and have lower birth weights. No differences were observed in rates of respiratory distress, admission to the neonatal intensive care unit, or stillbirth between the ART and spontaneous conception cohorts. The odds of neonatal acidosis (OR 0.71, 95% CI0.63-0.81) were lower in the ART cohort. Although higher rates of operative deliveries were seen for women who conceive using ART, neonatal outcomes were generally no different between the two cohorts. © 2017 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

  20. Abnormal human chorionic gonadotropin (hCG) trends after transfer of multiple embryos resulting in viable singleton pregnancies.

    Science.gov (United States)

    Brady, Paula C; Farland, Leslie V; Missmer, Stacey A; Racowsky, Catherine; Fox, Janis H

    2017-12-19

    The purpose of this study is to investigate whether abnormal hCG trends occur at a higher incidence among women conceiving singleton pregnancies following transfer of multiple (two or more) embryos (MET), as compared to those having a single embryo transfer (SET). Retrospective cohort study was performed of women who conceived singleton pregnancies following fresh or frozen autologous IVF/ICSI cycles with day 3 or day 5 embryo transfers between 2007 and 2014 at a single academic medical center. Cycles resulting in one gestational sac on ultrasound followed by singleton live birth beyond 24 weeks of gestation were included. Logistic regression models adjusted a priori for patient age at oocyte retrieval and day of embryo transfer were used to estimate the Odds Ratio of having an abnormal hCG rise (defined as a rise or hCG rises between the first and second measurements, compared to 2.7% (n = 17) of patients undergoing SET (OR 2.16, 95% CI 1.26-3.71). Among patients with initially abnormal hCG rises who had a third level checked (89%), three-quarters had normal hCG rises between the second and third measurements. Patients who deliver singletons following MET were more likely to have suboptimal initial hCG rises, potentially due to transient implantation of other non-viable embryo(s). While useful for counseling, these findings should not change standard management of abnormal hCG rises following IVF. The third hCG measurements may clarify pregnancy prognosis.

  1. Random searching

    International Nuclear Information System (INIS)

    Shlesinger, Michael F

    2009-01-01

    There are a wide variety of searching problems from molecules seeking receptor sites to predators seeking prey. The optimal search strategy can depend on constraints on time, energy, supplies or other variables. We discuss a number of cases and especially remark on the usefulness of Levy walk search patterns when the targets of the search are scarce.

  2. Search Patterns

    CERN Document Server

    Morville, Peter

    2010-01-01

    What people are saying about Search Patterns "Search Patterns is a delight to read -- very thoughtful and thought provoking. It's the most comprehensive survey of designing effective search experiences I've seen." --Irene Au, Director of User Experience, Google "I love this book! Thanks to Peter and Jeffery, I now know that search (yes, boring old yucky who cares search) is one of the coolest ways around of looking at the world." --Dan Roam, author, The Back of the Napkin (Portfolio Hardcover) "Search Patterns is a playful guide to the practical concerns of search interface design. It cont

  3. Perinatal outcomes among singletons after assisted reproductive technology with single-embryo or double-embryo transfer versus no assisted reproductive technology.

    Science.gov (United States)

    Martin, Angela S; Chang, Jeani; Zhang, Yujia; Kawwass, Jennifer F; Boulet, Sheree L; McKane, Patricia; Bernson, Dana; Kissin, Dmitry M; Jamieson, Denise J

    2017-04-01

    To examine outcomes of singleton pregnancies conceived without assisted reproductive technology (non-ART) compared with singletons conceived with ART by elective single-embryo transfer (eSET), nonelective single-embryo transfer (non-eSET), and double-embryo transfer with the establishment of 1 (DET -1) or ≥2 (DET ≥2) early fetal heartbeats. Retrospective cohort using linked ART surveillance data and vital records from Florida, Massachusetts, Michigan, and Connecticut. Not applicable. Singleton live-born infants. None. Preterm birth (PTB Reproductive Medicine. All rights reserved.

  4. Parents' anxiety and depression symptoms after successful infertility treatment and spontaneous conception: does singleton/twin pregnancy matter?

    Science.gov (United States)

    Tendais, I; Figueiredo, B

    2016-10-01

    Does mode of conception [spontaneous/after infertility treatment (IT)], type of pregnancy (singleton/twin) and parent gender have an effect on anxiety and depression levels and trajectories during pregnancy and the post-partum period? Conception after IT was associated with a transitory increase in anxiety during the perinatal period for parents of singletons, while for IT parents of twins higher levels of psychopathological symptoms tended to persist during pregnancy and the post-partum period. Most previous studies have shown that successful IT is not associated with poor psychological well-being during pregnancy and the post-partum period, but there is also some evidence for heightened pregnancy-related anxiety, lower self-esteem and lower self-efficacy. Parents of twins experience increased postnatal anxiety and depression. This prospective longitudinal study assessed 267 couples (N = 534) at each trimester of pregnancy, after childbirth and at 3 months post-partum. The sample comprised 36 couples who had conceived after IT (19 twin pairs and 17 singletons) and 231 couples who had conceived spontaneously (SC; 28 twin pairs and 203 singletons). Couples were recruited at four public hospitals in Portugal, and self-report measures of anxiety and depression symptoms were administered. IT parents reported higher anxiety after childbirth than parents who SC, regardless of pregnancy type. IT parents of twins showed higher anxiety at mid-pregnancy, as well as higher anxiety and depression at 3 months post-partum than IT parents of singletons. Among IT mothers, those who had twins exhibited higher depression after childbirth than those who had singletons. Differences according to mode of conception, pregnancy type and parents gender over time were also noted. During pregnancy, IT parents of twins showed no significant change in depression scores, while the other groups depression scores statistically significantly decreased over time. From pregnancy to the post

  5. History effects in visual search for monsters: search times, choice biases, and liking.

    Science.gov (United States)

    Chetverikov, Andrey; Kristjansson, Árni

    2015-02-01

    Repeating targets and distractors on consecutive visual search trials facilitates search performance, whereas switching targets and distractors harms search. In addition, search repetition leads to biases in free choice tasks, in that previously attended targets are more likely to be chosen than distractors. Another line of research has shown that attended items receive high liking ratings, whereas ignored distractors are rated negatively. Potential relations between the three effects are unclear, however. Here we simultaneously measured repetition benefits and switching costs for search times, choice biases, and liking ratings in color singleton visual search for "monster" shapes. We showed that if expectations from search repetition are violated, targets are liked to be less attended than otherwise. Choice biases were, on the other hand, affected by distractor repetition, but not by target/distractor switches. Target repetition speeded search times but had little influence on choice or liking. Our findings suggest that choice biases reflect distractor inhibition, and liking reflects the conflict associated with attending to previously inhibited stimuli, while speeded search follows both target and distractor repetition. Our results support the newly proposed affective-feedback-of-hypothesis-testing account of cognition, and additionally, shed new light on the priming of visual search.

  6. Intrauterine death in singleton pregnancies with trisomy 21, 18, 13 and monosomy X

    Directory of Open Access Journals (Sweden)

    Vanessa Vigna Goulart

    2016-04-01

    Full Text Available Summary A retrospective study from November 2004 to May 2012, conducted at the Obstetric Clinic of Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (HC-FMUSP, which included 92 singleton pregnancies with prenatal diagnosis of trisomy of chromosome 21 (T21, 18, 13 (T13/18 and monosomy X (45X, with diagnosis performed until the 26th week of pregnancy. The aim of the study was to describe the frequency and to investigate predictors of spontaneous fetal death (FD. Diagnosis (T21, n=36; T13/18, n=25; 45X, n=31 was made at a mean gestational age of 18.3±3.7 weeks, through chorionic villus biopsy (n=22,24%, amniocentesis (n=66, 72% and cordocentesis (n=4, 4%. Major malformations were present in 45 (49%; with hydrops in 32 (35% fetuses, more frequently in 45X [n=24/31, 77% vs. T21 (n=6/36, 17% and T13/18 (n=2/25, 8%, p<0.001]. Specialized fetal echocardiography was performed in 60% (55/92. Of these, 60% (33/55 showed changes in heart morphology and/or function. Fetuses with T13/18 had a higher incidence of cardiac anomalies [60 vs. 25% (T21 and 29% (45X, p= 0.01]. FD occurred in 55 (60% gestations, being more frequent in 45X [n=26/31, 84% vs. T21 (n=13/36, 36% and T13/18 (n=16/25, 64%, p<0.01]. Stepwise analysis showed a correlation between hydrops and death in fetuses with T21 (LR= 4.29; 95CI=1.9-8.0, p<0.0001. In fetuses with 45X, the presence of echocardiographic abnormalities was associated with lower risk of FD (LR= 0.56; 95CI=0.27- 0.85, p=0.005. No predictive factors were identified in the T13/18 group. Intra- uterine lethality of aneuploid fetuses is high. Occurrence of hydrops increases risk of FD in pregnancies with T21. In pregnancies with 45X, the occurrence of echocardiographic changes reduces this risk.

  7. Personalized Search

    CERN Document Server

    AUTHOR|(SzGeCERN)749939

    2015-01-01

    As the volume of electronically available information grows, relevant items become harder to find. This work presents an approach to personalizing search results in scientific publication databases. This work focuses on re-ranking search results from existing search engines like Solr or ElasticSearch. This work also includes the development of Obelix, a new recommendation system used to re-rank search results. The project was proposed and performed at CERN, using the scientific publications available on the CERN Document Server (CDS). This work experiments with re-ranking using offline and online evaluation of users and documents in CDS. The experiments conclude that the personalized search result outperform both latest first and word similarity in terms of click position in the search result for global search in CDS.

  8. The Colombo Twin and Singleton Follow-up Study: a population based twin study of psychiatric disorders and metabolic syndrome in Sri Lanka.

    Science.gov (United States)

    Jayaweera, Kaushalya; Aschan, Lisa; Pannala, Gayani; Adikari, Anushka; Glozier, Nicholas; Ismail, Khalida; Pariante, Carmine M; Rijsdijk, Fruhling; Siribaddana, Sisira; Zavos, Helena M S; Zunszain, Patricia A; Sumathipala, Athula; Hotopf, Matthew

    2018-01-17

    The disease burden related to mental disorders and metabolic syndrome is growing in low-and middle-income countries (LMIC). The Colombo Twin and Singleton Study (COTASS) is a population-based sample of twins and singletons in Colombo, Sri Lanka. Here we present prevalence estimates for metabolic syndrome (metS) and mental disorders from a follow-up (COTASS-2) of the original study (COTASS-1), which was a mental health survey. In COTASS-2, participants completed structured interviews, anthropometric measures and provided fasting blood and urine samples. Depressive disorder, depressive symptoms, anxiety symptoms, post-traumatic stress disorder (PTSD) and hazardous alcohol use were ascertained with structured psychiatric screens (Composite International Diagnostic Interview (CIDI), Beck Depression Inventory (BDI-II), Generalised Anxiety Disorder Questionnaire (GAD-7), PTSD Checklist - Civilian Version (PCL-C), and Alcohol Use Disorders Identification Test (AUDIT)). We defined metS according to the International Diabetes Federation (IDF) criteria and the revised National Cholesterol Education Programme Adult Treatment Panel (NCEP ATP III) criteria. We estimated the prevalence of psychiatric disorders and metS and metS components, and associations with gender, education and age. Two thousand nine hundred thirty-four twins and 1035 singletons were followed up from COTASS-1 (83.4 and 61.8% participation rate, respectively). Prevalence estimates for depressive disorder (CIDI), depressive symptoms (BDI ≥ 16), anxiety symptoms (GAD-7 ≥ 10) and PTSD (PCL-C DSM criteria) were 3.8, 5.9, 3.6, and 4.5% respectively for twins and 3.9, 9.8, 5.1 and 5.4% for singletons. 28.1 and 30.9% of male twins and singletons respectively reported hazardous alcohol use. Approximately one third met the metS criteria (IDF: 27.4% twins, 44.6% singletons; NCEP ATP III: 30.6% twins, 48.6% singletons). The most prevalent components were central obesity (59.2% twins, 71.2% singletons) and

  9. What Drives Memory-Driven Attentional Capture? The Effects of Memory Type, Display Type, and Search Type

    Science.gov (United States)

    Olivers, Christian N. L.

    2009-01-01

    An important question is whether visual attention (the ability to select relevant visual information) and visual working memory (the ability to retain relevant visual information) share the same content representations. Some past research has indicated that they do: Singleton distractors interfered more strongly with a visual search task when they…

  10. The effect of gestational diabetes, pre-gravid maternal obesity, and their combination ('diabesity') on outcomes of singleton gestations.

    Science.gov (United States)

    Blickstein, Isaac; Doyev, Reut; Trojner Bregar, Andreja; Bržan Šimenc, Gabrijela; Verdenik, Ivan; Tul, Natasa

    2018-03-01

    To assess the effect of the combination of gestational diabetes mellitus (GDM) and pre-gravid obesity ('diabesity') in singleton gestations. We compared perinatal outcomes of singleton gestations in mothers with GDM and pre-gravid obesity, with GDM but with normal pre-gravid BMI, and obese mothers without GDM. We compared diabesity mothers (n = 1525, 24.4% of mothers with GDM, 9.9% of all obese women) to mothers with GDM but with normal BMI (n = 4704, 75.6% of mothers with GDM) and to obese mothers without GDM (n = 13,937, 90.1% of all obese mothers). Obesity, with and without GDM, increased the odds of having chronic hypertension whereas preeclampsia appears to be influenced by obesity only, as were the risk of births at 4000 g, low 5-min Apgar scores and NICU admissions. Obesity (without diabetes) is more frequently associated with adverse perinatal outcomes than diabesity or GDM in non-obese mothers. A campaign to decrease pre-gravid obesity should have at least the same priority as any campaign to control GDM.

  11. Obstetric and perinatal outcomes of singletons after single blastocyst transfer: is there any difference according to blastocyst morphology?

    Science.gov (United States)

    Bouillon, Céline; Celton, Noémie; Kassem, Sandra; Frapsauce, Cynthia; Guérif, Fabrice

    2017-08-01

    A strong correlation between blastocyst morphology and implantation has been shown by many studies. The consequences and effects of assisted reproductive techniques on children's short and long-term health have always been a source of discussion. The obstetric and perinatal outcome of singletons according to blastocyst morphology has rarely been evaluated. The aim of this observational study is to determine whether a relationship exists between blastocyst morphology and obstetric and perinatal outcomes. A total of 799 singleton clinical pregnancies were analysed after transfer of a single fresh blastocyst on day 5 between 2006 and 2013. Blastocysts were divided into four groups based on their morphology on day 5: group 1 = good morphology blastocysts; group 2 = fair morphology blastocysts; group 3 = poor morphology blastocysts and group 4 = early (B1/B2) blastocysts. Obstetric and perinatal outcomes were compared between the four groups. After adjustment for some confounding variables, main obstetric and perinatal outcomes after transfer of blastocysts with poor morphological characteristics were not associated with increased adverse obstetric and perinatal events. Sex ratio was significantly higher in group 1 compared with groups 2, 3 and 4, and in Group 2 compared with Group 3 (P < 0.001) even after adjustment (P < 0.05). Copyright © 2017 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

  12. Faceted Search

    CERN Document Server

    Tunkelang, Daniel

    2009-01-01

    We live in an information age that requires us, more than ever, to represent, access, and use information. Over the last several decades, we have developed a modern science and technology for information retrieval, relentlessly pursuing the vision of a "memex" that Vannevar Bush proposed in his seminal article, "As We May Think." Faceted search plays a key role in this program. Faceted search addresses weaknesses of conventional search approaches and has emerged as a foundation for interactive information retrieval. User studies demonstrate that faceted search provides more

  13. Inter-trial priming does not affect attentional priority in asymmetric visual search

    Directory of Open Access Journals (Sweden)

    Liana eAmunts

    2014-08-01

    Full Text Available Visual search is considerably speeded when the target’s characteristics remain constant across successive selections. Here, we investigated whether such inter-trial priming increases the target’s attentional priority, by examining whether target repetition reduces search efficiency during serial search. As the study of inter-trial priming requires the target and distractors to exchange roles unpredictably, it has mostly been confined to singleton searches, which typically yield efficient search. We therefore resorted to two singleton searches known to yield relatively inefficient performance, that is, searches in which the target does not pop out. Participants searched for a veridical angry face among neutral ones or vice-versa, either upright or inverted (Experiment 1 or for a Q among Os or vice-versa (Experiment 2. In both experiments, we found substantial intertrial priming that did not improve search efficiency. In addition, intertrial priming was asymmetric and occurred only when the more salient target repeated. We conclude that intertrial priming does not modulate attentional priority allocation and that it occurs in asymmetric search only when the target is characterized by an additional feature that is consciously perceived.

  14. New population-based references for birth weight, length, and head circumference in singletons and twins from 23 to 43 gestation weeks.

    Science.gov (United States)

    Sankilampi, Ulla; Hannila, Marja-Leena; Saari, Antti; Gissler, Mika; Dunkel, Leo

    2013-09-01

    Birth size curves are needed for clinical and epidemiological purposes. We constructed birth weight (BW), length (BL), and head circumference (BHC) references, assessed effects of twinness and parity, and defined cut-off points for small, appropriate, and large for gestational age. Birth register data of all 753,036 infants born in 1996-2008 in Finland were cleaned to create references reflecting optimal intrauterine growth. The final data included 533,666 singletons and 15,033 twins (median gestation weeks (gws) 40.0 and 37.1, respectively, 41.6% primiparous). Sex-specific BW, BL, and BHC references were constructed from 23 to 43 gws separately for singletons and twins born to primiparous or multiparous mothers. GAMLSS method was used for modelling. In singletons from 36 gws onwards, increased BW and BL were observed in comparison to previous reference from 1979-1983. Twins diverged from singletons from 30 gws onwards. At 37.0 gws, mean BW was 400 g lower and mean BL 1.2 cm shorter than in singletons. From 30 gws onwards, birth size was larger in infants of multiparous than primiparous mothers. Population-based birth size references are available for the evaluation of birth size. Accounting for plurality and parity improves the accuracy of birth size evaluation.

  15. Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  16. Non-singleton colors are not attended faster than categories, but they are encoded faster: A combined approach of behavior, modeling and ERPs.

    Science.gov (United States)

    Callahan-Flintoft, Chloe; Wyble, Brad

    2017-11-01

    The visual system is able to detect targets according to a variety of criteria, such as by categorical (letter vs digit) or featural attributes (color). These criteria are often used interchangeably in rapid serial visual presentation (RSVP) studies but little is known about how rapidly they are processed. The aim of this work was to compare the time course of attentional selection and memory encoding for different types of target criteria. We conducted two experiments where participants reported one or two targets (T1, T2) presented in lateral RSVP streams. Targets were marked either by being a singleton color (red letter among black letters), being categorically distinct (digits among letters) or non-singleton color (target color letter among heterogeneously colored letters). Using event related potential (ERPs) associated with attention and memory encoding (the N2pc and the P3 respectively), we compared the relative latency of these two processing stages for these three kinds of targets. In addition to these ERP measures, we obtained convergent behavioral measures for attention and memory encoding by presenting two targets in immediate sequence and comparing their relative accuracy and proportion of temporal order errors. Both behavioral and EEG measures revealed that singleton color targets were attended much more quickly than either non-singleton color or categorical targets, and there was very little difference between attention latencies to non-singleton color and categorical targets. There was however a difference in the speed of memory encoding for non-singleton color and category latencies in both behavioral and EEG measures, which shows that encoding latency differences do not always mirror attention latency differences. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Prenatal screening at 11-13+6 weeks in assisted reproductive technology singleton pregnancies and those conceived naturally.

    Science.gov (United States)

    Gong, Meng; Shi, Hua; Zhang, Yu-guo; Ming, Lei

    2015-10-01

    To investigate whether assisted reproductive technology (ART) increases the risk of fetal chromosomal abnormalities. A total of 2034 singleton pregnant women were included in this retrospective study. They were divided into ART (574 fetuses) and control groups (1460 fetuses conceived naturally). All pregnant women received screening according to the Fetal Medicine Foundation, London 2004 Kypros H. Nicolaides guidelines at 11-13+6 weeks of gestation. Accordingly, women with value at risk of chromosomal abnormalities >1:250 underwent chorionic villus sampling or amniocentesis. Mean body mass index was 22.83 ± 3.27 versus 21.29 ± 2.81 kg/m(2) in the ART and control groups, respectively (P fetal chromosomal abnormalities. Additionally, fetus size in the ART group was bigger than that in the natural conception group. © 2015 Japan Society of Obstetrics and Gynecology.

  18. Velamentous Cord Insertion in a Singleton Pregnancy: An Obscure Cause of Emergency Cesarean—A Case Report

    Directory of Open Access Journals (Sweden)

    Juliana Rocha

    2012-01-01

    Full Text Available Approximately 2% of low-risk pregnant women still require an emergency Cesarean section after the onset of labor. Because it is likely that half of these cases are associated with placental and umbilical cord abnormalities, it is thought that prenatal detection of such abnormalities would reduce the number of emergency cesarean sections in low-risk women. Velamentous cord insertion is an abnormal cord insertion in which the umbilical vessels diverge as they traverse between the amnion and chorion before reaching the placenta. With a reported incidence of 1% in singleton pregnancies, it has been associated with several obstetric complications. This condition has been diagnosed by ultrasonography with a sensitivity of 67% and specificity of 100% in the second trimester. The present case highlights the importance of the systematic assessment of the placental cord insertion site at routine obstetric ultrasound and the potential of identifying pregnancies with velamentous insertion and, therefore, those at risk for obstetric complications.

  19. The influence of maternal glucose metabolism on fetal growth, development and morbidity in 917 singleton pregnancies in nondiabetic women.

    Science.gov (United States)

    Farmer, G; Russell, G; Hamilton-Nicol, D R; Ogenbede, H O; Ross, I S; Pearson, D W; Thom, H; Kerridge, D F; Sutherland, H W

    1988-03-01

    To study the effects on the fetus of variations in maternal glucose tolerance, a 25 g rapid intravenous glucose tolerance test was performed at or about 32 weeks gestation in 917 randomly selected nondiabetic women with singleton pregnancies. The results were withheld from the patients and their obstetricians and paediatricians, and no treatment or advice was offered. Fasting plasma glucose and indices of glucose disposal (including a new index which we have termed "summed glucose") were distributed unimodally, with no evidence of a separate pathological group towards the diabetic end of the distributions. Significant associations were found between maternal glucose metabolism and various measures of neonatal nutrition and morbidity, including the incidence of congenital malformations and morbidity related to asphyxia, suggesting that variations within the normal range in maternal glucose metabolism can influence growth and development in the fetus. These relationships were continuous throughout the range of maternal glucose tolerance and were not of predictive value in individual cases.

  20. Risk factors associated with preterm birth among singletons following assisted reproductive technology in Australia 2007–2009–a population-based retrospective study

    OpenAIRE

    Xu, Xu K; Wang, Yueping A; Li, Zhuoyang; Lui, Kei; Sullivan, Elizabeth A

    2014-01-01

    Background Preterm birth, a leading cause of neonatal death, is more common in multiple births and thus there has being an increasing call for reducing multiple births in ART. However, few studies have compared risk factors for preterm births amongst ART and non-ART singleton birth mothers. Methods A population-based study of 393,450 mothers, including 12,105 (3.1%) ART mothers, with singleton gestations born between 2007 and 2009 in 5 of the 8 jurisdictions in Australia. Univariable and mult...

  1. Hospitalization in adolescence and young adulthood among twins and singletons: a Swedish cohort study of subjects born between 1973 and 1983.

    Science.gov (United States)

    Bladh, Marie; Carstensen, John; Josefsson, Ann; Finnström, Orvar; Sydsjö, Gunilla

    2013-06-01

    Children born with non-optimal birth characteristics - that is, are small for gestational age and/or preterm - have an increased risk for several long-term effects such as neurological sequelae and chronic disease. The purpose of this study was to examine whether twins exhibited a different outcome, compared with singletons, in terms of hospitalization during adolescence and early adulthood, and to what extent differences remain when considering the divergence in birth characteristics between singletons and twins. Persons born between 1973 and 1983 in Sweden and surviving until age 13 were included and followed until the end of 2006. Data on birth characteristics, parental socio-demographic factors, and hospitalizations were collected from national registers. Adjusting for parental socio-demographic factors, twins had a higher risk of being hospitalized than singletons (odds ratio, OR = 1.17, 95% confidence interval, CI = 1.10-1.25) and more often due to 'Congenital anomalies' (OR = 1.18, 95% CI = 1.06-1.28), 'Infections' (OR = 1.14; 95% CI = 1.08-1.20), 'External causes of illness' (OR = 1.10, 95% CI = 1.06-1.15), and 'Diseases of the nervous system' (OR = 1.18, 95% CI = 1.10-1.26). Stratifying for birth characteristics, this difference diminishes, and for some diagnoses non-optimal twins seem to do slightly better than non-optimal singletons. Thus, twins with non-optimal birth characteristics had a lower risk of hospitalization than non-optimal singletons on, for example, 'Congenital anomalies' and 'Diseases of the nervous system' (OR = 0.86, 95% CI = 0.77-0.96; OR = 0.88, 95% CI = 0.81-0.97, respectively) and Total (any) hospitalization (OR = 0.87, 95% CI = 0.83-0.92). Among those with optimal birth characteristics, twins had an increased hospitalization due to 'External causes of illness' (OR = 1.07, 95% CI = 1.02-1.13) compared with optimal singletons. Twins have higher hospitalization rates than singletons. In stratifying for birth characteristics, this

  2. Autonomous search

    CERN Document Server

    Hamadi, Youssef; Saubion, Frédéric

    2012-01-01

    Autonomous combinatorial search (AS) represents a new field in combinatorial problem solving. Its major standpoint and originality is that it considers that problem solvers must be capable of self-improvement operations. This is the first book dedicated to AS.

  3. A comparison of perinatal outcomes in singletons and multiples born after in vitro fertilization or intracytoplasmic sperm injection stratified for neonatal risk criteria

    NARCIS (Netherlands)

    van Heesch, M.M.J.; Evers, J.L.H.; Dumoulin, J.C.M.; van der Hoeven, M.A.H.B.; van Beijsterveldt, C.E.M.; Bonsel, G.J.; Dykgraaf, R.H.M.; van Goudoever, J.B.; Koopman-Esseboom, C.; Nelen, W.L.D.M.; Steiner, K.; Tamminga, P.; Tonch, N.; van Zonneveld, P.; Dirksen, C.D.

    2014-01-01

    Objective To compare perinatal singleton and multiple outcomes in a large Dutch in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) population and within risk subgroups. Newborns were assigned to a risk category based on gestational age, birthweight, Apgar score and congenital

  4. A comparison of perinatal outcomes in singletons and multiples born after in vitro fertilization or intracytoplasmic sperm injection stratified for neonatal risk criteria

    NARCIS (Netherlands)

    Heesch, M.M. van; Evers, J.L.H.; Dumoulin, J.C.; Hoeven, M.A. van der; Beijsterveldt, C.E. van; Bonsel, G.J.; Dykgraaf, R.H.; Goudoever, J.B. van; Koopman-Esseboom, C.; Nelen, W.L.D.M.; Steiner, K.; Tamminga, P.; Tonch, N.; Zonneveld, P. van; Dirksen, C.D.

    2014-01-01

    OBJECTIVE: To compare perinatal singleton and multiple outcomes in a large Dutch in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) population and within risk subgroups. Newborns were assigned to a risk category based on gestational age, birthweight, Apgar score and congenital

  5. Clinical Significance of Preterm Singleton Pregnancies Complicated by Placental Abruption following Preterm Premature Rupture of Membranes Compared with Those without p-PROM

    Science.gov (United States)

    Suzuki, Shunji

    2012-01-01

    The purpose of this paper was to examine the obstetric and neonatal outcomes of preterm singleton pregnancies complicated by placental abruption following preterm premature rupture of membranes (p-PROM) compared with those without p-PROM. We reviewed the obstetric records of 95 singleton deliveries complicated by placental abruption at 22–36 weeks' gestation. The incidence of placental abruption in singleton pregnancies with p-PROM was 4.7%, and the crude odds ratio of placental abruption for women following p-PROM was 6.50 (P < 0.01). Of the 95 cases of placental abruption in preterm singleton deliveries, 64 cases (67.4%) occurred without p-PROM and 31 cases (32.6%) occurred following p-PROM. The incidence of histological chorioamnionitis stage III in the patients following p-PROM was significantly higher than that in the patients without p-PROM (P = 0.02). The rate of emergency Cesarean deliveries associated with nonreassuring fetal status (NRFS) in the patients following p-PROM was significantly lower than that in the patients without p-PROM. However, there were no significant differences in the maternal and neonatal outcomes between the patients with and without p-PROM. Although p-PROM may be one of important risk factors for placental abruption associated with chorioamnionitis, it may not influence the perinatal outcomes in preterm placental abruption. PMID:22690341

  6. Neonatal and maternal outcomes comparing women undergoing two in vitro fertilization (IVF) singleton pregnancies and women undergoing one IVF twin pregnancy.

    Science.gov (United States)

    Sazonova, Antonina; Källen, Karin; Thurin-Kjellberg, Ann; Wennerholm, Ulla-Britt; Bergh, Christina

    2013-03-01

    To compare outcomes for women undergoing two in vitro fertilization (IVF) pregnancies with singletons and women undergoing one IVF twin pregnancy. The concept of single-embryo transfer in IVF has reduced the risks of both maternal and neonatal complications, but there is still a discussion of whether or not twins are a desired outcome of IVF. Registry study. Not applicable. All reported twins after IVF with double-embryo transfer (n = 1,982) and their mothers (n = 991) and all mothers (n = 921) who gave birth to two IVF singletons (n = 1,842). None. Maternal and neonatal outcomes including severe neonatal morbidity. Preterm birth, very preterm birth, low birth weight, very low birth weight, and small for gestational age were dramatically increased for IVF twins compared with two IVF singletons with the same mother, with adjusted odds ratios from 4 to 16. Significantly higher rates of respiratory complications, sepsis, and jaundice were detected among the IVF twins. Significantly higher rates of preeclampsia, preterm premature rupture of the membranes, and cesarean section were observed for IVF twin pregnancies. The neonatal and maternal outcomes were dramatically better for women undergoing two IVF singleton pregnancies compared with one IVF twin pregnancy after double-embryo transfer. These results support single-embryo transfer to minimize the risks associated with twin pregnancies. Copyright © 2013 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  7. Outcome of Multifetal Pregnancy Reduction in Women with a Dichorionic Triamniotic Triplet Pregnancy to a Singleton Pregnancy : A Retrospective Nationwide Cohort Study

    NARCIS (Netherlands)

    Van De Mheen, L.; Everwijn, S. M P; Haak, M. C.; Manten, G. T R; Zondervan, H. A.; Knapen, M. F C M; Engels, M. A J; Erwich, J. J H M; Coumans, A. B.; Van Vugt, J. M G; Bilardo, C. M.; Van Pampus, M. G.; De Groot, C. J M; Mol, B. W J; Pajkrt, E.

    2016-01-01

    Objective: To study the pregnancy outcomes of women with a dichorionic triamniotic triplet pregnancy that was reduced to a singleton pregnancy and to review the literature. Methods: We performed a nationwide retrospective cohort study. We compared time to delivery and perinatal mortality in

  8. Outcome of Multifetal Pregnancy Reduction in Women with a Dichorionic Triamniotic Triplet Pregnancy to a Singleton Pregnancy: A Retrospective Nationwide Cohort Study

    NARCIS (Netherlands)

    van de Mheen, L.; Everwijn, S. M. P.; Haak, M. C.; Manten, G. T. R.; Zondervan, H. A.; Knapen, M. F. C. M.; Engels, M. A. J.; Erwich, J. J. H. M.; Coumans, A. B.; van Vugt, J. M. G.; Bilardo, C. M.; van Pampus, M. G.; de Groot, C. J. M.; Mol, B. W. J.; Pajkrt, E.

    2016-01-01

    To study the pregnancy outcomes of women with a dichorionic triamniotic triplet pregnancy that was reduced to a singleton pregnancy and to review the literature. We performed a nationwide retrospective cohort study. We compared time to delivery and perinatal mortality in dichorionic triplet

  9. Outcome of Multifetal Pregnancy Reduction in Women with a Dichorionic Triamniotic Triplet Pregnancy to a Singleton Pregnancy : A Retrospective Nationwide Cohort Study

    NARCIS (Netherlands)

    van de Mheen, L.; Everwijn, S. M. P.; Haak, M. C.; Manten, G. T. R.; Zondervan, H. A.; Knapen, M. F. C. M.; Engels, M. A. J.; Erwich, J. J. H. M.; Coumans, A. B.; van Vugt, J. M. G.; Bilardo, C. M.; van Pampus, M. G.; de Groot, C. J. M.; Mol, B. W. J.; Pajkrt, E.

    2016-01-01

    Objective:To study the pregnancy outcomes of women with a dichorionic triamniotic triplet pregnancy that was reduced to a singleton pregnancy and to review the literature. Methods: We performed a nationwide retrospective cohort study. We compared time to delivery and perinatal mortality in

  10. Increased time to pregnancy is associated with less optimal neurological condition in 4-year-old singletons, in vitro fertilization itself is not

    NARCIS (Netherlands)

    Schendelaar, P.; van den Heuvel, Edwin; Heineman, M. J.; La Bastide-Van Gemert, S.; Middelburg, K. J.; Seggers, Jorien; Hadders-Algra, M.

    2014-01-01

    STUDY QUESTION: Does ovarian hyperstimulation, the in vitro procedures required for in vitro fertilization (IVF)/intracytoplasmic sperm injection or the combination of both, affect the neurological outcome of 4-year-old singletons? SUMMARY ANSWER: Ovarian hyperstimulation, the in vitro procedure and

  11. Increased time to pregnancy is associated with less optimal neurological condition in 4-year-old singletons, in vitro fertilization itself is not

    NARCIS (Netherlands)

    Schendelaar, P.; van den Heuvel, E. R.; Heineman, M. J.; La Bastide-van Gemert, S.; Middelburg, K. J.; Seggers, J.; Hadders-Algra, M.

    2014-01-01

    Does ovarian hyperstimulation, the in vitro procedures required for in vitro fertilization (IVF)/ intracytoplasmic sperm injection or the combination of both, affect the neurological outcome of 4-year-old singletons? Ovarian hyperstimulation, the in vitro procedure and the combination of both, were

  12. Loop electrosurgical excision of the cervix and subsequent risk for spontaneous preterm delivery: a population-based study of singleton deliveries during a 9-year period

    DEFF Research Database (Denmark)

    Noehr, Bugge; Jensen, Allan; Frederiksen, Kirsten

    2009-01-01

    OBJECTIVE: Our aim was to assess the association between loop electrosurgical excision procedure (LEEP) and the subsequent risk for spontaneous preterm delivery, with the use of population-based data from various nationwide registries. STUDY DESIGN: The study population consisted of all singleton...

  13. Mortality among twins and singletons in sub-Saharan Africa between 1995 and 2014: a pooled analysis of data from 90 Demographic and Health Surveys in 30 countries.

    Science.gov (United States)

    Monden, Christiaan W S; Smits, Jeroen

    2017-07-01

    Sub-Saharan Africa has the world's highest under-5 and neonatal mortality rates as well as the highest naturally occurring twin rates. Twin pregnancies carry high risk for children and mothers. Under-5 mortality has declined in sub-Saharan Africa over the last decades. It is unknown whether twins have shared in this reduction. We pooled data from 90 Demographic and Health Surveys for 30 sub-Saharan Africa countries on births reported between 1995 and 2014. We used information on 1 685 110 singleton and 56 597 twin livebirths to compute trends in mortality rates for singletons and twins. We examined whether the twin-singleton rate ratio can be attributed to biological, socioeconomic, care-related factors, or birth size, and estimated the mortality burden among sub-Saharan African twins. Under-5 mortality among twins has declined from 327·7 (95% CI 312·0-343·5) per 1000 livebirths in 1995-2001 to 213·0 (196·7-229·2) in 2009-14. This decline of 35·0% was much less steep than the 50·6% reduction among singletons (from 128·6 [95% CI 126·4-130·8] per 1000 livebirths in 1995-2001 to 63·5 [61·6-65·3] in 2009-14). Twins account for an increasing share of under-5 deaths in sub-Saharan Africa: currently 10·7% of under-5 mortality and 15·1% of neonatal mortality. We estimated that about 315 000 twins (uncertainty interval 289 000-343 000) die in sub-Saharan African each year. Excess twin mortality cannot be explained by common risk factors for under-5 mortality, including birthweight. The difference with singletons was especially stark for neonatal mortality (rate ratio 5·0, 95% CI 4·5-5·6). 51·7% of women pregnant with twins reported receiving medical assistance at birth. The fate of twins in sub-Saharan Africa is lagging behind that of singletons. An alarming one-fifth of twins in the region dies before age 5 years, three times the mortality rate among singletons. Twins account for a substantial and growing share of under-5 and neonatal

  14. Delivery of double singleton pregnancies in a woman with a double uterus, double cervix, and complete septate vagina.

    Science.gov (United States)

    Yang, Ming-Jie; Tseng, Jen-Yu; Chen, Chih-Yao; Li, Hsin-Yang

    2015-12-01

    Uterine anomalies involving a double uterus, double cervix, also known as didelphys uterus, and complete septate vagina are rarely seen and have an associated fertility problem. However, artificial reproductive technology with embryo transfers can help solve this fertility challenge. Conception in the uterus in just one side is commonly seen for embryos, which are always transferred through the usually used (dilated) vagina. We here present a patient with the above uterine anomaly who conceived with the aid of in vitro fertilization and embryo transfer to both uterine cavities under general anesthesia, which resulted in successful double singleton pregnancies with one fetus in each uterus. With intensive prenatal care, the pregnancy course for each fetus was rather uneventful. Although both fetuses were in cephalic presentation, cesarean section was performed at the 39(th) week of gestation with good outcomes in order to preclude anticipated difficulties if the baby had been delivered through the rarely dilated vagina. However, order of birth between the two fetuses was a crucial decision during the operation. Copyright © 2015. Published by Elsevier Taiwan.

  15. Maternal and fetal arterial blood gas data in normotensive, singleton, isoflurane anesthetized sheep at 124-126 days of gestation.

    Science.gov (United States)

    Loughran, Claire M; Kemp, Matthew W; Musk, Gabrielle C

    2017-07-01

    The aim of this case series was to describe the differences between maternal and fetal blood-gas results during anesthesia. Sixteen singleton adult merino ewes weighing 60.1 ± 5.1 kg at 125.7 d (124 to 126 d) gestation were anesthetized. Maternal (radial) and fetal (umbilical) arterial blood gas samples were collected 79 ± 6 min after the start of anesthesia if maternal mean arterial pressure (MAP) was stable and > 65 mmHg. Fetal pH, partial arterial pressure of oxygen ( P aO 2 ), glucose, arterial hemoglobin oxygen saturation (SaO 2 ), sodium, and chloride were significantly lower and fetal partial arterial pressure of carbon dioxide ( P aCO 2 ), lactate, hematocrit, total hemoglobin, potassium, and calcium were significantly higher than maternal blood-gas values. Fetal pH, P aO 2 , and BE were lower and fetal lactate was higher than fetal umbilical arterial samples previously reported, which may indicate a non-reassuring fetal status. Further refinement of the ovine experimental model is warranted with fetal monitoring during maternal anesthesia.

  16. References of birth weights for gestational age and sex from a large cohort of singleton births in cameroon.

    Science.gov (United States)

    Kemfang Ngowa, Jean Dupont; Domkam, Irénée; Ngassam, Anny; Nguefack-Tsague, Georges; Dobgima Pisoh, Walter; Noa, Cyrille; Kasia, Jean Marie

    2014-01-01

    Objective. To establish the percentile charts of birth weights for gestational age and sex within the Cameroonian population. Methods. A review of medical records of infants born between January 2007 and December 2011 at the maternities of two hospitals in Cameroon, Central Africa. Multiple pregnancies, births of HIV infected women, stillbirths, and births with major fetal malformations were excluded. The smooth curves of birth weight for gestational age and sex were created using the Gamlss package under R.3.0.1 software. Results. The birth weights of 12837 live birth singleton infants born to HIV negative women between 28 and 42 weeks of gestation were analyzed to construct the birth weight curves for gestational age and sex. The smoothed percentile curves of birth weights for gestational age and sex of Cameroonian infants have demonstrated an increasing slope until 40 weeks and then a plateau. There was a varied difference of distribution in birth weights for gestational age between Cameroonian, Botswanan, American, and French infants. Conclusion. We established the reference curves of birth weights for gestational age and sex for Cameroonians. The difference in birth weight curves noted between Cameroonian, Botswanan, American, and French infants suggests the importance of establishing the regional birth weight norms.

  17. References of Birth Weights for Gestational Age and Sex from a Large Cohort of Singleton Births in Cameroon

    Directory of Open Access Journals (Sweden)

    Jean Dupont Kemfang Ngowa

    2014-01-01

    Full Text Available Objective. To establish the percentile charts of birth weights for gestational age and sex within the Cameroonian population. Methods. A review of medical records of infants born between January 2007 and December 2011 at the maternities of two hospitals in Cameroon, Central Africa. Multiple pregnancies, births of HIV infected women, stillbirths, and births with major fetal malformations were excluded. The smooth curves of birth weight for gestational age and sex were created using the Gamlss package under R.3.0.1 software. Results. The birth weights of 12837 live birth singleton infants born to HIV negative women between 28 and 42 weeks of gestation were analyzed to construct the birth weight curves for gestational age and sex. The smoothed percentile curves of birth weights for gestational age and sex of Cameroonian infants have demonstrated an increasing slope until 40 weeks and then a plateau. There was a varied difference of distribution in birth weights for gestational age between Cameroonian, Botswanan, American, and French infants. Conclusion. We established the reference curves of birth weights for gestational age and sex for Cameroonians. The difference in birth weight curves noted between Cameroonian, Botswanan, American, and French infants suggests the importance of establishing the regional birth weight norms.

  18. Perinatal outcome of singleton siblings born after assisted reproductive technology and spontaneous conception: Danish national sibling-cohort study.

    Science.gov (United States)

    Henningsen, Anna-Karina Aaris; Pinborg, Anja; Lidegaard, Øjvind; Vestergaard, Christina; Forman, Julie Lyng; Andersen, Anders Nyboe

    2011-03-01

    To compare the perinatal outcome of singleton siblings conceived differently. National population-based registry study. Denmark, from 1994 to 2008. Pairs of siblings (13,692 pairs; n = 27,384 children) conceived after IVF, intracytoplasmatic sperm injection (ICSI), frozen embryo replacement (FER), or spontaneous conception subcategorized into five groups according to succession: [1] IVF-ICSI vs. spontaneous conception (n = 7,758), [2] IVF-ICSI vs. FER (n = 716), [3] FER vs. FER (n = 34), [4] IVF-ICSI vs. IVF-ICSI (n = 2,876), and [5] spontaneous conception vs. spontaneous conception (n = 16,000). Observations were obtained from national registries. Birth weight, gestational age, low birth weight (conception method. Higher risk of low birth weight with (odds ratio [OR], 1.4; 95%CI, 1.1-1.7] and preterm birth (OR, 1.3; 95% CI, 1.1-1.6] was observed in IVF/ICSI compared with spontaneous conception. When differentiating between order and mode of conception, it seems that assisted reproductive technology plays a role in mean birth weight and risk of low birth weight and preterm birth. Birth weight was higher in siblings born after FER compared with fresh embryos replacement. Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  19. Amnioinfusion for women with a singleton breech presentation and a previous failed external cephalic version: a randomized controlled trial.

    Science.gov (United States)

    Diguisto, Caroline; Winer, Norbert; Descriaud, Celine; Tavernier, Elsa; Weymuller, Victoire; Giraudeau, Bruno; Perrotin, Franck

    2018-04-01

    Our trial aimed to assess the effectiveness of amnioinfusion for a second attempt at external cephalic version (ECV). This open randomized controlled trial was planned with a sequential design. Women at a term ≥36 weeks of gestation with a singleton fetus in breech presentation and a first unsuccessful ECV were recruited in two level-3 maternity units. They were randomly allocated to transabdominal amnioinfusion with a 500-mL saline solution under ultrasound surveillance or no amnioinfusion before the second ECV attempt. Trained senior obstetricians performed all procedures. The primary outcome was the cephalic presentation rate at delivery. Analyses were conducted according to intention to treat (NCT00465712). Recruitment difficulties led to stopping the trial after a 57-month period, 119 women were randomized: 59 allocated to amnioinfusion + ECV and 60 to ECV only. Data were analyzed without applying the sequential feature of the design. The rate of cephalic presentation at delivery did not differ significantly according to whether the second version attempt was or was not preceded by amnioinfusion (20 versus 12%, p = .20). Premature rupture of the membranes occurred for 15% of the women in the amnioinfusion group. Amnioinfusion before a second attempt to external version does not significantly increase the rate of cephalic presentation at delivery.

  20. Limitations of the equivalence between spatial and ensemble estimators in the case of a single-tone excitation.

    Science.gov (United States)

    Monsef, Florian; Cozza, Andrea

    2011-10-01

    The ensemble-average value of the mean-square pressure is often assessed by using the spatial-average technique, underlying an equivalence principle between spatial and ensemble estimators. Using the ideal-diffuse-field model, the accuracy of the spatial-average method has been studied theoretically forty years ago in the case of a single-tone excitation. This study is revisited in the present work on the basis of a more realistic description of the sound field accounting for a finite number of plane waves. The analysis of the spatial-average estimator is based on the study of its convergence rate. Using experimental data from practical examples, it is shown that the classical expression underestimates the estimator uncertainty even for frequencies greater than Schroeder's frequency, and that the number of plane waves may act as lower bound on the spatial-average estimator accuracy. The comparison of the convergence rate with an ensemble-estimator shows that the two statistics cannot be regarded as equivalent in a general case. © 2011 Acoustical Society of America

  1. Total and differential leukocyte count percentiles in healthy singleton term women during the first stage of labor.

    Science.gov (United States)

    Lurie, Samuel; Weiner, Eran; Golan, Abraham; Sadan, Oscar

    2014-01-01

    To establish leukocyte count and differential percentiles in healthy singleton term laboring women during spontaneous normal vaginal labor following an uncomplicated pregnancy. An analysis of the records of all women (n = 762) who delivered at our delivery ward during a 2-month period was performed. After exclusion for cesarean delivery, induction of labor, pregnancy complications, preterm labor, multiple pregnancy, fever on admission, and lack of full blood count on admission, 365 parturient women during the 1st stage of labor were included in the final analysis. The total and differential leukocyte counts were determined by standard procedure by an automated cell counter. The leukocyte count range on admission to the delivery ward during the 1st stage of labor in healthy parturient women was between 4.4 × and 21.7 × 10(3)/µl and the 99th percentile limit was 20.06 × 10(3)/µl. The total leukocyte count was not influenced by cervical dilatation, ruptured membranes, or the presence and regularity of uterine contractions. An observed leukocyte count within the 99th percentile limit (20.06 × 10(3)/µl) in an otherwise normal parturient woman is reassuring in the absence of other clinical evidence. © 2014 S. Karger AG, Basel.

  2. Costs and effects of screening and treating low risk women with a singleton pregnancy for asymptomatic bacteriuria, the ASB study

    Directory of Open Access Journals (Sweden)

    Kazemier Brenda M

    2012-06-01

    Full Text Available Abstract Background The prevalence of asymptomatic bacteriuria (ASB in pregnancy is 2-10% and is associated with both maternal and neonatal adverse outcomes as pyelonephritis and preterm delivery. Antibiotic treatment is reported to decrease these adverse outcomes although the existing evidence is of poor quality. Methods/Design We plan a combined screen and treat study in women with a singleton pregnancy. We will screen women between 16 and 22 weeks of gestation for ASB using the urine dipslide technique. The dipslide is considered positive when colony concentration ≥105 colony forming units (CFU/mL of a single microorganism or two different colonies but one ≥105 CFU/mL is found, or when Group B Streptococcus bacteriuria is found in any colony concentration. Women with a positive dipslide will be randomly allocated to receive nitrofurantoin or placebo 100 mg twice a day for 5 consecutive days (double blind. Primary outcomes of this trial are maternal pyelonephritis and/or preterm delivery before 34 weeks. Secondary outcomes are neonatal and maternal morbidity, neonatal weight, time to delivery, preterm delivery rate before 32 and 37 weeks, days of admission in neonatal intensive care unit, maternal admission days and costs. Discussion This trial will provide evidence for the benefit and cost-effectiveness of dipslide screening for ASB among low risk women at 16–22 weeks of pregnancy and subsequent nitrofurantoin treatment. Trial registration Dutch trial registry: NTR-3068

  3. Internet Search Engines

    OpenAIRE

    Fatmaa El Zahraa Mohamed Abdou

    2004-01-01

    A general study about the internet search engines, the study deals main 7 points; the differance between search engines and search directories, components of search engines, the percentage of sites covered by search engines, cataloging of sites, the needed time for sites appearance in search engines, search capabilities, and types of search engines.

  4. Stronger interference from distractors in the right hemifield during visual search.

    Science.gov (United States)

    Carlei, Christophe; Kerzel, Dirk

    2018-03-01

    The orientation-bias hypothesis states that there is a bias to attend to the right visual hemifield (RVF) when there is spatial competition between stimuli in the left and right hemifield [Pollmann, S. (1996). A pop-out induced extinction-like phenomenon in neurologically intact subjects. Neuropsychologia, 34(5), 413-425. doi: 10.1016/0028-3932(95)00125-5 ]. In support of this hypothesis, stronger interference was reported for RVF distractors with contralateral targets. In contrast, previous studies using rapid serial visual presentation (RSVP) found stronger interference from distractors in the left visual hemifield (LVF). We used the additional singleton paradigm to test whether this discrepancy was due to the different distractor features that were employed (colour vs. orientation). Interference from the colour distractor with contralateral targets was larger in the RVF than in the LVF. However, the asymmetrical interference disappeared when observers had to search for an inconspicuous colour target instead of the inconspicuous shape target. We suggest that the LVF orienting-bias is limited to situations where search is driven by bottom-up saliency (singleton search) instead of top-down search goals (feature search). In contrast, analysis of the literature suggests the opposite for the LVF bias in RSVP tasks. Thus, the attentional asymmetry may depend on whether the task involves temporal or spatial competition, and whether search is based on bottom-up or top-down signals.

  5. Effect of frozen/thawed embryo transfer on birthweight, macrosomia, and low birthweight rates in US singleton infants.

    Science.gov (United States)

    Litzky, Julia F; Boulet, Sheree L; Esfandiari, Navid; Zhang, Yujia; Kissin, Dmitry M; Theiler, Regan N; Marsit, Carmen J

    2017-12-29

    Singleton infants conceived using assisted reproductive technology have lower average birthweights than naturally conceived infants and are more likely to be born low birthweight (macrosomia (>4000 g) and low birthweight (macrosomia and low birthweight were evaluated using multivariable predicted marginal proportions from logistic regression models. In total, 180,184 singleton, term infants were included, with 55,898 (31.02%) having been conceived from frozen/thawed embryos. Frozen/thawed embryo transfer was associated with, on average, a 142 g increase in birthweight compared with infants born after fresh embryo transfer (P macrosomia following frozen/thawed embryo transfer was greater than that following fresh embryo transfer, but the risk of low birthweight among frozen/thawed embryo transfer infants was significantly decreased in comparison with fresh embryo transfer infants. Copyright © 2018 Elsevier Inc. All rights reserved.

  6. Use of multiple linear regression and logistic regression models to investigate changes in birthweight for term singleton infants in Scotland.

    Science.gov (United States)

    Bonellie, Sandra R

    2012-10-01

    To illustrate the use of regression and logistic regression models to investigate changes over time in size of babies particularly in relation to social deprivation, age of the mother and smoking. Mean birthweight has been found to be increasing in many countries in recent years, but there are still a group of babies who are born with low birthweights. Population-based retrospective cohort study. Multiple linear regression and logistic regression models are used to analyse data on term 'singleton births' from Scottish hospitals between 1994-2003. Mothers who smoke are shown to give birth to lighter babies on average, a difference of approximately 0.57 Standard deviations lower (95% confidence interval. 0.55-0.58) when adjusted for sex and parity. These mothers are also more likely to have babies that are low birthweight (odds ratio 3.46, 95% confidence interval 3.30-3.63) compared with non-smokers. Low birthweight is 30% more likely where the mother lives in the most deprived areas compared with the least deprived, (odds ratio 1.30, 95% confidence interval 1.21-1.40). Smoking during pregnancy is shown to have a detrimental effect on the size of infants at birth. This effect explains some, though not all, of the observed socioeconomic birthweight. It also explains much of the observed birthweight differences by the age of the mother.   Identifying mothers at greater risk of having a low birthweight baby as important implications for the care and advice this group receives. © 2012 Blackwell Publishing Ltd.

  7. The impact of gestational diabetes mellitus on postpartum urinary incontinence: a longitudinal cohort study on singleton pregnancies.

    Science.gov (United States)

    Chuang, C-M; Lin, I-F; Horng, H-C; Hsiao, Y-H; Shyu, I-L; Chou, P

    2012-10-01

    To determine whether gestational diabetes mellitus (GDM) is an independent risk factor for postpartum urinary incontinence in singleton pregnancies. A longitudinal cohort study. A single tertiary-care hospital in Taiwan. Pregnant women with term deliveries between 2002 and 2007 (n = 6653) were consecutively recruited. Logistic regression models were fitted based on generalised estimating equation methods to derive odds ratios for occurrences of type-specific urinary incontinence in the third trimester and at four time-points over 2 years during the postpartum period. Evaluation of whether GDM is an independent risk factor for postpartum urinary incontinence. The full model analysis revealed that GDM was an independent risk factor for all type-specific urinary incontinence (odds ratio [95% confidence interval]: 1.97 [1.56-2.51], 3.11 [2.18-4.43] and 2.73 [1.70-4.40] for stress, urge and mixed incontinence, respectively]. Compared with women without GDM, women with GDM tended to exhibit more severe symptoms of stress incontinence for up to 2 years postpartum, whereas for urge or mixed incontinence, more severe symptoms were found only for 6 months postpartum. Evaluation of quality of life using the Incontinence Impact Questionnaire 7 suggested that women with GDM requiring insulin treatment had a higher likelihood of functional impairment than women with GDM requiring conservative treatment only or women without GDM (P risk factor for postpartum urinary incontinence and had a significant impact on quality of life. Women with GDM should be provided with timely consultation and support once urinary incontinence occurs. © 2012 The Authors BJOG An International Journal of Obstetrics and Gynaecology © 2012 RCOG.

  8. Fear of childbirth predicts postpartum depression: a population-based analysis of 511 422 singleton births in Finland.

    Science.gov (United States)

    Räisänen, Sari; Lehto, Soili M; Nielsen, Henriette Svarre; Gissler, Mika; Kramer, Michael R; Heinonen, Seppo

    2013-11-28

    To study how reproductive risks and perinatal outcomes are associated with postpartum depression treated in specialised healthcare defined according to the International Classification of Diseases (ICD)-10 codes, separately among women with and without a history of depression. A retrospective population-based case-control study. Data gathered from three national health registers for the years 2002-2010. All singleton births (n=511 422) in Finland. Prevalence of postpartum depression and the risk factors associated with it. In total, 0.3% (1438 of 511 422) of women experienced postpartum depression, the prevalence being 0.1% (431 of 511 422) in women without and 5.3% (1007 of 18 888) in women with a history of depression. After adjustment for possible covariates, a history of depression was found to be the strongest risk factor for postpartum depression. Other strong predisposing factors for postpartum depression were fear of childbirth, caesarean birth, nulliparity and major congenital anomaly. Specifically, among the 30% of women with postpartum depression but without a history of depression, postpartum depression was shown to be associated with fear of childbirth (adjusted OR (aOR 2.71, 95% CI 1.98 to 3.71), caesarean birth (aOR 1.38, 95% CI 1.08 to 1.77), preterm birth (aOR 1.65, 95% CI 1.08 to 2.56) and major congenital anomaly (aOR 1.67, 95% CI 1.15 to 2.42), compared with women with no postpartum depression and no history of depression. A history of depression was found to be the most important predisposing factor of postpartum depression. Women without previous episodes of depression were at an increased risk of postpartum depression if adverse events occurred during the course of pregnancy, especially if they showed physician-diagnosed fear of childbirth.

  9. Singleton Sequence Type 382, an Emerging Clonal Group of Listeria monocytogenes Associated with Three Multistate Outbreaks Linked to Contaminated Stone Fruit, Caramel Apples, and Leafy Green Salad

    OpenAIRE

    Chen, Yi; Luo, Yan; Pettengill, James; Timme, Ruth; Melka, David; Doyle, Matthew; Jackson, Alikeh; Parish, Mickey; Hammack, Thomas S.; Allard, Marc W.; Brown, Eric W.; Strain, Errol A.

    2017-01-01

    ABSTRACT Three multistate outbreaks between 2014 and 2016, involving case patients in and outside the United States, were linked to stone fruit, caramel apples, and packaged leafy green salad contaminated with Listeria monocytogenes singleton sequence type 382 (ST382), a serotype IVb-v1 clone with limited genomic divergence. Isolates from these outbreaks and other ST382 isolates not associated with these outbreaks were analyzed by whole-genome sequencing (WGS) analysis. The primary difference...

  10. Periconceptional undernutrition programs changes in insulin-signaling molecules and microRNAs in skeletal muscle in singleton and twin fetal sheep.

    Science.gov (United States)

    Lie, Shervi; Morrison, Janna L; Williams-Wyss, Olivia; Suter, Catherine M; Humphreys, David T; Ozanne, Susan E; Zhang, Song; Maclaughlin, Severence M; Kleemann, David O; Walker, Simon K; Roberts, Claire T; McMillen, I Caroline

    2014-01-01

    Maternal undernutrition around the time of conception is associated with an increased risk of insulin resistance in adulthood. We determined the effect of maternal undernutrition in the periconceptional period (PCUN, i.e., 60 days prior to 6 days after conception) and the preimplantation period (PIUN, i.e., 0-6 days after conception) on mRNA expression and protein abundance of key insulin-signaling molecules as well as the global microRNA expression in quadriceps muscle of singleton and twin fetal sheep in late gestation. In singleton fetuses, exposure to PCUN resulted in lower protein abundance of PIK3CB (P < 0.01), PRKCZ (P < 0.05), and pPRKCZ (Thr410) (P < 0.05) in skeletal muscle compared to controls. In PIUN singletons, there was a higher protein abundance of IRS1 (P < 0.05), PDPK1 (P < 0.05), and SLC2A4 (P < 0.05) compared to controls. In twins, PCUN resulted in higher protein abundance of IRS1 (P < 0.05), AKT2 (P < 0.05), PDPK1 (P < 0.05), and PRKCZ (P < 0.001), while PIUN also resulted in higher protein abundance of IRS1 (P < 0.05), PRKCZ (P < 0.001), and SLC2A4 (P < 0.05) in fetal muscle compared to controls. There were specific patterns of the types and direction of changes in the expression of 22 microRNAs in skeletal muscle after exposure to PCUN or PIUN and clear differences in these patterns between singleton and twin pregnancies. These findings provide evidence that maternal undernutrition around the time of conception induces changes in the expression of microRNAs, which may play a role in altering the abundance of the key insulin-signaling molecules in skeletal muscle and in the association between PCUN undernutrition and insulin resistance in adult life.

  11. Visual working memory simultaneously guides facilitation and inhibition during visual search.

    Science.gov (United States)

    Dube, Blaire; Basciano, April; Emrich, Stephen M; Al-Aidroos, Naseem

    2016-07-01

    During visual search, visual working memory (VWM) supports the guidance of attention in two ways: It stores the identity of the search target, facilitating the selection of matching stimuli in the search array, and it maintains a record of the distractors processed during search so that they can be inhibited. In two experiments, we investigated whether the full contents of VWM can be used to support both of these abilities simultaneously. In Experiment 1, participants completed a preview search task in which (a) a subset of search distractors appeared before the remainder of the search items, affording participants the opportunity to inhibit them, and (b) the search target varied from trial to trial, requiring the search target template to be maintained in VWM. We observed the established signature of VWM-based inhibition-reduced ability to ignore previewed distractors when the number of distractors exceeds VWM's capacity-suggesting that VWM can serve this role while also representing the target template. In Experiment 2, we replicated Experiment 1, but added to the search displays a singleton distractor that sometimes matched the color (a task-irrelevant feature) of the search target, to evaluate capture. We again observed the signature of VWM-based preview inhibition along with attentional capture by (and, thus, facilitation of) singletons matching the target template. These findings indicate that more than one VWM representation can bias attention at a time, and that these representations can separately affect selection through either facilitation or inhibition, placing constraints on existing models of the VWM-based guidance of attention.

  12. Vaginal progesterone vs intramuscular 17α-hydroxyprogesterone caproate for prevention of recurrent spontaneous preterm birth in singleton gestations: systematic review and meta-analysis of randomized controlled trials.

    Science.gov (United States)

    Saccone, G; Khalifeh, A; Elimian, A; Bahrami, E; Chaman-Ara, K; Bahrami, M A; Berghella, V

    2017-03-01

    Randomized controlled trials (RCTs) have recently compared intramuscular 17α-hydroxyprogesterone caproate (17-OHPC) with vaginal progesterone for reducing the risk of spontaneous preterm birth (SPTB) in singleton gestations with prior SPTB. The aim of this systematic review and meta-analysis was to evaluate the efficacy of vaginal progesterone compared with 17-OHPC in prevention of SPTB in singleton gestations with prior SPTB. Searches of electronic databases were performed to identify all RCTs of asymptomatic singleton gestations with prior SPTB that were randomized to prophylactic treatment with either vaginal progesterone (intervention group) or intramuscular 17-OHPC (comparison group). No restrictions for language or geographic location were applied. The primary outcome was SPTB EMBARAZOS CON FETO ÚNICO: REVISIÓN SISTEMÁTICA Y METAANÁLISIS DE ENSAYOS CONTROLADOS ALEATORIOS: RESUMEN OBJETIVO: Recientemente se han realizado varios ensayos controlados aleatorios (ECA) que comparaban el caproato de 17α-hidroxiprogesterona (17-OHPC, por sus siglas en inglés) por vía intramuscular con la progesterona por vía vaginal para la reducción del riesgo de parto pretérmino espontáneo (PPTE) en embarazos con feto único de gestantes con historial de PPTE. El objetivo de esta revisión sistemática y metaanálisis fue evaluar la eficacia de la progesterona vaginal en comparación con la 17-OHPC en la prevención de embarazos con feto único de gestantes con historial de PPTE. MÉTODOS: Se realizaron búsquedas en bases de datos electrónicas para identificar todos los ECA con embarazos de feto único asintomáticos con historial de PPTE antes de ser asignados al azar a un tratamiento profiláctico, ya fuera con progesterona vaginal (grupo de intervención) o con 17-OHPC intramuscular (grupo de control). No se aplicaron restricciones respecto al idioma o la ubicación geográfica. El resultado primario fue PPTE embarazos de feto único e historial de PPTE. Sin

  13. Risk factors associated with preterm birth among singletons following assisted reproductive technology in Australia 2007-2009--a population-based retrospective study.

    Science.gov (United States)

    Xu, Xu K; Wang, Yueping A; Li, Zhuoyang; Lui, Kei; Sullivan, Elizabeth A

    2014-12-07

    Preterm birth, a leading cause of neonatal death, is more common in multiple births and thus there has being an increasing call for reducing multiple births in ART. However, few studies have compared risk factors for preterm births amongst ART and non-ART singleton birth mothers. A population-based study of 393,450 mothers, including 12,105 (3.1%) ART mothers, with singleton gestations born between 2007 and 2009 in 5 of the 8 jurisdictions in Australia. Univariable and multivariable logistic regression models were conducted to evaluate socio-demographic, medical and pregnancy factors associated with preterm births in contrasting ART and non-ART mothers. Ten percent of singleton births to ART mothers were preterm compared to 6.8% for non-ART mothers (P disadvantaged (12.4% in the lowest quintile vs 20.7%), less likely to be smokers (3.8% vs 19.4%), more likely to be first time mothers (primiparous 62.4% vs 40.5%), had more preexisting hypertension and complications during pregnancy. Irrespective of the mode of conception, preexisting medical and pregnancy complications of hypertension, diabetes and antepartum hemorrhages were consistently associated with preterm birth. In contrast, socio-demographic variables, namely young and old maternal age (34), socioeconomic disadvantage (most disadvantaged quintile Odds Ratio (OR) 0.95, 95% Confidence Interval (CI): 0.77-1.17), smoking (OR 1.12, 95%CI: 0.79-1.61) and priminarity (OR 1.19, 95% CI: 1.05-1.35, AOR not significant) shown to be associated with elevated risk of preterm birth for non-ART mothers were not demonstrated for ART mothers, even after adjusting for potential confounders. Nonetheless, in multivariable analysis, the association between ART and the elevated risk for singleton preterm birth persisted after controlling for all included confounding medical, pregnancy and socio-economic factors (AOR 1.51, 95% CI: 1.42-1.61). Preterm birth rate is approximately one-and-a-half-fold higher in ART mothers than non

  14. Fertility treatment and child intelligence, attention, and executive functions in 5-year-old singletons: a cohort study.

    Science.gov (United States)

    Bay, B; Mortensen, E L; Kesmodel, U S

    2014-12-01

    To assess the association of fertility treatment and subfertility with offspring intelligence, attention, and executive functions in 5-year-old singletons. Follow-up study. Denmark 2003-2008. A cohort of 1782 children sampled from the Danish National Birth Cohort. The children were tested with a neuropsychological battery at age five. In addition to tests of intelligence, attention and executive functions, the follow up included extensive information on important covariates. The analyses were conducted using multiple linear regression and adjusted for parental educational level, maternal intelligence, age, parity, body mass index, smoking in pregnancy, alcohol consumption in pregnancy and child gender, child age, and examiner. Wechsler Preschool and Primary Scale of Intelligence-Revised, the Test of Everyday Attention for Children at Five, and the Behavior Rating Inventory of Executive Functions scores. A consistent pattern of nonsignificantly lower scores were only observed for intelligence and executive functions in children born after fertility treatment or by subfertile parents when the results were unadjusted for maternal intelligence and parental educational level. When adjusted for these and other covariates, there were no significant mean differences in intelligence (mean difference -2.8, 95% CI -7.8, 2.2), overall attention (-0.1, 95% CI -0.6, 0.3), or parent-rated executive functions (-0.1, 95% CI -3.0, 2.9) between children born after spontaneous conception and children born to parents conceiving after fertility treatment. Similarly, there were no significant mean differences in intelligence (mean difference 0.6, 95% CI -2.2, 3.4), overall attention (0.1, 95% CI -0.2, 0.4), or parent-rated executive functions (1.0, 95% CI -1.8, 3.7) between children born after spontaneous conception and children born to subfertile parents waiting more than 12 months before conceiving naturally. This study suggests that parental subfertility and fertility treatment are

  15. EFFECT OF EARLY PREGNANCY BODY MASS INDEX ON PREGNANCY OUTCOMES IN WOMEN DELIVERING SINGLETON BABIES- AN OBSERVATIONAL STUDY

    Directory of Open Access Journals (Sweden)

    Divya Vishnu

    2017-02-01

    Full Text Available BACKGROUND Maternal overweight/obesity causes many complications during pregnancy and delivery. It can also increase neonatal and infant morbidity and mortality. BMI is an important measure of under/overweight. This observational study examines the correlation between maternal Body Mass Index (BMI with maternal outcome in women. MATERIALS AND METHODS This study was conducted at Department of Obstetrics and Gynaecology, Government Medical College, Kottayam, Kerala, for a period of one year. A sample of 300 pregnant women with intrauterine pregnancy of gestational age <12 weeks at first visit was taken for this study with an age between 18 and 35 years with singleton pregnancy. BMI of these women were calculated and they were classified into two categories (BMI <23 kg/m2 and BMI ≥23 kg/m2 . The Chi-square test was done to find the association of BMI and various maternal outcomes. RESULTS In the sample of 300 pregnant women, 39% were having BMI <23 kg/m2 and 61% were having BMI ≥23 kg/m2 . Pregnant women with BMI ≥23 kg/m2 were found to have significantly increased risk of developing gestational hypertension, gestational diabetes and macrosomia. We found that a significantly increased need of induction and increased risk of developing intrapartum and postpartum complications in those with BMI ≥23 kg/m2 . Our study also found out that an increased incidence of elective as well as emergency caesareans and increased risk of neonatal complications in women whose BMI ≥23 kg/m2 . CONCLUSION Adverse maternal and perinatal outcomes are significantly related to extremes of BMI categories and least complications were seen in normal BMI group. Therefore, it is ideal to reduce the body weight to an optimal level so that the complications, which are attributed to overweight and obesity can be reduced. We recommended future research on the association of BMI and maternal outcomes involving large samples comparable to those done in developed countries.

  16. Interrupted Visual Searches Reveal Volatile Search Memory

    Science.gov (United States)

    Shen, Y. Jeremy; Jiang, Yuhong V.

    2006-01-01

    This study investigated memory from interrupted visual searches. Participants conducted a change detection search task on polygons overlaid on scenes. Search was interrupted by various disruptions, including unfilled delay, passive viewing of other scenes, and additional search on new displays. Results showed that performance was unaffected by…

  17. Contribution of risk factors to extremely, very and moderately preterm births - register-based analysis of 1,390,742 singleton births.

    Directory of Open Access Journals (Sweden)

    Sari Räisänen

    Full Text Available Preterm birth, defined as birth occurring before 37 weeks gestation, is one of the most significant contributors to neonatal mortality and morbidity, with long-term adverse consequences for health, and cognitive outcome.The aim of the present study was to identify risk factors of preterm birth (≤36+6 weeks gestation among singleton births and to quantify the contribution of risk factors to socioeconomic disparities in preterm birth.A retrospective population-based case-control study using data derived from the Finnish Medical Birth Register. A total population of singleton births in Finland from 1987-2010 (n = 1,390,742 was reviewed.Among all singleton births (n = 1,390,742, 4.6% (n = 63,340 were preterm (<37 weeks, of which 0.3% (n = 4,452 were classed as extremely preterm, 0.4% (n = 6,213 very preterm and 3.8% (n = 54,177 moderately preterm. Smoking alone explained up to 33% of the variation in extremely, very and moderately preterm birth incidence between high and the low socioeconomic status (SES groups. Reproductive risk factors (placental abruption, placenta previa, major congenital anomaly, amniocentesis, chorionic villus biopsy, anemia, stillbirth, small for gestational age (SGA and fetal sex altogether explained 7.7-25.0% of the variation in preterm birth between SES groups.Smoking explained about one third of the variation in preterm birth groups between SES groups whereas the contribution of reproductive risk factors including placental abruption, placenta previa, major congenital anomaly, amniocentesis, chorionic villus biopsy, anemia, stillbirth, SGA and fetal sex was up to one fourth.

  18. Association of Maternal Obesity With Longitudinal Ultrasonographic Measures of Fetal Growth: Findings From the NICHD Fetal Growth Studies-Singletons.

    Science.gov (United States)

    Zhang, Cuilin; Hediger, Mary L; Albert, Paul S; Grewal, Jagteshwar; Sciscione, Anthony; Grobman, William A; Wing, Deborah A; Newman, Roger B; Wapner, Ronald; D'Alton, Mary E; Skupski, Daniel; Nageotte, Michael P; Ranzini, Angela C; Owen, John; Chien, Edward K; Craigo, Sabrina; Kim, Sungduk; Grantz, Katherine L; Louis, Germaine M Buck

    2018-01-01

    Despite the increasing prevalence of pregravid obesity, systematic evaluation of the association of maternal obesity with fetal growth trajectories is lacking. To characterize differences in fetal growth trajectories between obese and nonobese pregnant women, and to identify the timing of any observed differences. The Eunice Kennedy Shriver National Institute of Child Health and Human Development Fetal Growth Studies-Singletons study enrolled cohorts of pregnant women at 12 US health care institutions. Obese women (with prepregnancy body mass index > 30) and nonobese women (prepregnancy body mass indexes, 19-29.9) without major chronic diseases were recruited between 8 weeks and 0 days' gestation and 13 weeks and 6 days' gestation. A mixed longitudinal randomization scheme randomized participants into 1 of 4 schedules for 2-dimensional and 3-dimensional ultrasonograms to capture weekly fetal growth data throughout the remainder of their pregnancies. On each ultrasonogram, fetal humerus length, femur length, biparietal diameter, head circumference, and abdominal circumference were measured. Fetal growth curves were estimated using linear mixed models with cubic splines. Median differences in the fetal measures at each gestational week of the obese and nonobese participants were examined using the likelihood ratio and Wald tests after adjustment for maternal characteristics. The study enrolled 468 obese and 2334 nonobese women between 8 weeks and 0 days' gestation and 13 weeks and 6 days' gestation. After a priori exclusion criteria, 443 obese and 2320 nonobese women composed the final cohort. Commencing at 21 weeks' gestation, femur length and humerus length were significantly longer for fetuses of obese woman than those of nonobese women. Differences persisted in obese and nonobese groups through 38 weeks' gestation (median femur length, 71.0 vs 70.2 mm; P = .01; median humerus length, 62.2 vs 61.6 mm; P = .03). Averaged across gestation, head circumference

  19. Fetal fibronectin testing for prevention of preterm birth in singleton pregnancies with threatened preterm labor: a systematic review and metaanalysis of randomized controlled trials.

    Science.gov (United States)

    Berghella, Vincenzo; Saccone, Gabriele

    2016-10-01

    Fetal fibronectin is an extracellular matrix glycoprotein that is produced by amniocytes and cytotrophoblasts and has been shown to predict spontaneous preterm birth. The aim of this systematic review and metaanalysis of randomized clinical trials was to evaluate the effect of the use of fetal fibronectin in the prevention of preterm birth in singleton pregnancies with threatened preterm labor. The research was conducted with the use of MEDLINE, EMBASE, Web of Sciences, Scopus, ClinicalTrial.gov, OVID, and Cochrane Library as electronic databases from the inception of each database to February 2016. Selection criteria included randomized clinical trials of singleton gestations with threatened preterm labor that were assigned randomly to management based on fetal fibronectin results (ie, intervention group) or not (ie, comparison group). Types of participants included women with singleton gestations at 23 0/7 to 34 6/7 weeks with threatened preterm labor. Studies that included management that was also based on the use of sonographic cervical length were excluded. The primary outcome was preterm birth at birth at control group. No differences were found in the number of women who delivered within 7 days (12.8% vs 14.5%; relative risk, 0.76; 95% confidence interval, 0.47-1.21), in the mean of gestational age at delivery (mean difference, 0.20 week; 95% confidence interval, -0.26 to 0.67), in the rate of maternal hospitalization (27.4% vs 26.9%; relative risk, 1.07; 95% confidence interval, 0.80-1.44), in the use of tocolysis (25.3% vs 28.2%; relative risk, 0.97; 95% confidence interval, 0.75-1.24), antenatal steroids (29.2% vs 29.2%; relative risk, 1.05; 95% confidence interval, 0.79-1.39), in the mean time in the triage unit (mean difference, 0.60 hour; 95% confidence interval, -0.03 to 1.23) and in neonatal outcomes that included respiratory distress syndrome (1.3% vs 1.5%; relative risk, 0.91; 95% confidence interval, 0.06-14.06), and admission to the neonatal

  20. Cervical length screening for prevention of preterm birth in singleton pregnancy with threatened preterm labor: systematic review and meta-analysis of randomized controlled trials using individual patient-level data.

    Science.gov (United States)

    Berghella, V; Palacio, M; Ness, A; Alfirevic, Z; Nicolaides, K H; Saccone, G

    2017-03-01

    Cervical length screening by transvaginal sonography (TVS) has been shown to be a good predictive test for spontaneous preterm birth (PTB) in symptomatic singleton pregnancy with threatened preterm labor (PTL). The aim of this review and meta-analysis of individual participant data was to evaluate the effect of knowledge of the TVS cervical length (CL) in preventing PTB in singleton pregnancies presenting with threatened PTL. We searched the Cochrane Pregnancy and Childbirth Group's Trials Register and the Cochrane Complementary Medicine Field's Trials Register (May 2016) and reference lists of retrieved studies. Selection criteria included randomized controlled trials of singleton gestations with threatened PTL randomized to management based mainly on CL screening (intervention group), or CL screening with no knowledge of results or no CL screening (control group). Participants included women with singleton gestations at 23 + 0 to 36 + 6 weeks with threatened PTL. We contacted corresponding authors of included trials to request access to the data and perform a meta-analysis of individual participant data. Data provided by the investigators were merged into a master database constructed specifically for the review. The primary outcome was PTB DE PARTO PREMATURO: REVISIÓN SISTEMÁTICA Y METAANÁLISIS DE ENSAYOS CONTROLADOS ALEATORIZADOS HACIENDO USO DE LOS DATOS INDIVIDUALES DE LAS PACIENTES: RESUMEN OBJETIVO: El cribado mediante la longitud cervical obtenida con ecografía transvaginal (ETV) ha demostrado ser una buena prueba para la predicción del parto pretérmino espontáneo (PPTE) en embarazos con feto único sintomáticos debido a la amenaza de parto pretérmino (PPT). El objetivo de esta revisión y metaanálisis de los datos de participantes individuales fue evaluar el efecto de medir la longitud cervical (LC) mediante ETV con el fin de prevenir el parto prematuro en embarazos únicos con amenaza de PPT. MÉTODOS: Se realizaron búsquedas en los ficheros

  1. Hyperthyroidism is associated with work disability and loss of labour market income. A Danish register-based study in singletons and disease-discordant twin pairs.

    Science.gov (United States)

    Brandt, Frans; Thvilum, Marianne; Hegedüs, Laszlo; Brix, Thomas Heiberg

    2015-11-01

    To examine the risk of disability pension and changes in labour market income in patients with hyperthyroidism. From a 5% random sample of the Danish population and twins from the Danish Twin Registry we identified 1942 hyperthyroid singletons and 7768 non-hyperthyroid (matched 1:4) controls as well as 584 same-sex twin pairs discordant for hyperthyroidism. Singletons and twins were followed for a mean of 9 years (range 1-20). Cox regression analysis was used to examine the risk of disability pension and a difference-in-differences model was used to evaluate changes in labour market income. Hyperthyroid individuals had an increased risk of receiving disability pension: hazard ratio (HR) was 1.88, (95% CI: 1.57-2.24). Subdividing as to the cause of hyperthyroidism did not change this finding: Graves' disease (GD) HR was 1.51 (95% CI: 0.87-2.63) and toxic nodular goitre (TNG) HR was 2.10 (95% CI: 1.02-4.36). With respect to labour market income, the income of hyperthyroid individuals increased on average 1189 € less than their controls (Pmarket income, were seen within monozygotic twin pairs discordant for hyperthyroidism. Hyperthyroidism is associated with severe work disability as reflected by an 88% increased risk of receiving disability pension and a significant loss of labour market income. Similar results in monozygotic twins discordant for hyperthyroidism suggest that genetic confounding is unlikely. © 2015 European Society of Endocrinology.

  2. Outcome of singleton preterm small for gestational age infants born to mothers with pregnancy-induced hypertension. A population-based study.

    Science.gov (United States)

    Regev, Rivka H; Arnon, Shmuel; Litmanovitz, Ita; Bauer-Rusek, Sofia; Boyko, Valentina; Lerner-Geva, Liat; Reichman, Brian

    2015-04-01

    Pregnancy-induced hypertension (PIH) has been associated with a decreased risk of infant mortality in small for gestational age (SGA) preterm infants. To evaluate the influence of PIH on mortality and major neonatal morbidities in singleton preterm SGA infants, in the presence and absence of acute pregnancy complications. Population-based observational study of singleton SGA infants, born at 24 to 32 weeks gestation in the period 1995-2010 (n = 2139). Multivariable logistic regression analyses were used to assess the independent effect of PIH on mortality and neonatal morbidities. Acute pregnancy complications comprised premature labor, premature rupture of membranes >6 h, antepartum hemorrhage and clinical chorioamnionitis. In the absence of pregnancy complications, the odds ratio (95% confidence interval) for mortality (0.77; 0.50-1.16), survival without severe neurological morbidity (1.14; 0.79-1.65) and survival without bronchopulmonary dysplasia (BPD) (0.85; 0.59-1.21) were similar in the PIH versus no-PIH groups. In the presence of pregnancy complications, mortality (0.76; 0.40-1.44), survival without severe neurological morbidity (1.16; 0.64-2.12) and survival without BPD (1.04; 0.58-1.86) were also similar in the PIH versus no-PIH groups. PIH was not associated with improved outcome in preterm SGA infants, both in the presence and absence of acute pregnancy complications.

  3. Medical outcome of 8-year-old singleton ICSI children (born >or=32 weeks' gestation) and a spontaneously conceived comparison group.

    Science.gov (United States)

    Belva, F; Henriet, S; Liebaers, I; Van Steirteghem, A; Celestin-Westreich, S; Bonduelle, M

    2007-02-01

    There is little information about the long-term outcome of children born after ICSI. In this study, the eldest cohort of ICSI children worldwide, reaching the age of 8 years, was investigated at the prepubertal stage to monitor subsequent puberty and future fertility. To investigate possible health problems, a thorough medical and neurological examination was performed. Medical outcome of 8-year-old singletons (n=150) born through ICSI (>or=32 weeks) was compared with that of 147 singletons of the same age born after spontaneous conception (SC). Information about their general health was obtained from the parents by means of a questionnaire. Fifteen of 150 ICSI children experienced a major congenital malformation compared with 5/147 SC children (P Neurological examination did not show important differences between ICSI and SC children. ICSI children did not require more remedial therapy or surgery or hospitalization than SC children. Physical examination including a thorough neurological examination did not reveal important differences between the two groups. Major congenital malformations were significantly more frequent in the ICSI group. However, most of them were corrected by minor surgery. Further monitoring of these children at an older age is recommended.

  4. Search Term Reports

    Science.gov (United States)

    Learn what search terms brought users to choose your page in their search results, and what terms they entered in the EPA search box after visiting your page. Use this information to improve links and content on the page.

  5. Effect of Cervical Pessary on Spontaneous Preterm Birth in Women With Singleton Pregnancies and Short Cervical Length: A Randomized Clinical Trial.

    Science.gov (United States)

    Saccone, Gabriele; Maruotti, Giuseppe Maria; Giudicepietro, Antonia; Martinelli, Pasquale

    2017-12-19

    Spontaneous preterm birth is a major cause of perinatal morbidity and mortality. It is unclear if a cervical pessary can reduce the risk of spontaneous preterm delivery. To test whether in asymptomatic women with singleton pregnancies and no prior spontaneous preterm birth but with short cervical length on transvaginal ultrasound, use of a cervical pessary would reduce the rate of spontaneous preterm birth at less than 34 weeks of gestation. Parallel-group, nonblinded, randomized clinical trial conducted from March 1, 2016, to May 25, 2017, at a single center in Italy. Asymptomatic women with singleton gestations, no previous spontaneous preterm births, and cervical lengths of 25 mm or less at 18 weeks 0 days to 23 weeks 6 days of gestation were eligible. Patients were randomized 1:1 to receive either cervical pessary (n = 150) or no pessary (n = 150). The pessary was removed between 37 weeks 0 days and 37 weeks 6 days of gestation or earlier if clinically indicated. The control group received standard care. For cervical length of 20 mm or shorter, women in both groups were prescribed vaginal progesterone, 200 mg/d, until 36 weeks 6 days of gestation. No bed rest or activity restriction was recommended. The primary end point was spontaneous preterm birth at less than 34 weeks of gestation. Secondary outcomes were adverse events. Among 300 women who were randomized (mean age, 29 [SD, 6.3] years; mean gestational age, 22 [SD, 1.3] weeks), 100% completed the trial. The primary end point occurred in 11 women (7.3%) in the pessary group and 23 women (15.3%) in the control group (between-group difference, -8.0% [95% CI, -15.7% to -0.4]; relative risk, 0.48 [95% CI, 0.24-0.95]). During follow-up, the pessary group had a higher rate of increased or new vaginal discharge (86.7% vs 46.0%; between-group difference, +40.7% [95% CI, +30.1%-+50.3%]; relative risk, 1.88 [95% CI, 1.57-2.27]). Among women without prior spontaneous preterm birth who had asymptomatic

  6. submitter Searches at LEP

    CERN Document Server

    Kawagoe, Kiyotomo

    2001-01-01

    Searches for new particles and new physics were extensively performed at LEP. Although no evidence for new particle/physics was discovered, the null results set very stringent limits to theories beyond the standard model. In this paper, searches at LEP and anomalies observed in the searches are presented. Future prospect of searches at the new energy frontier machines is also discussed.

  7. Web Search Engines

    OpenAIRE

    Rajashekar, TB

    1998-01-01

    The World Wide Web is emerging as an all-in-one information source. Tools for searching Web-based information include search engines, subject directories and meta search tools. We take a look at key features of these tools and suggest practical hints for effective Web searching.

  8. Sound Search Engine Concept

    DEFF Research Database (Denmark)

    2006-01-01

    Sound search is provided by the major search engines, however, indexing is text based, not sound based. We will establish a dedicated sound search services with based on sound feature indexing. The current demo shows the concept of the sound search engine. The first engine will be realased June...

  9. How doctors search

    DEFF Research Database (Denmark)

    Lykke, Marianne; Price, Susan; Delcambre, Lois

    2012-01-01

    Professional, workplace searching is different from general searching, because it is typically limited to specific facets and targeted to a single answer. We have developed the semantic component (SC) model, which is a search feature that allows searchers to structure and specify the search...

  10. Large Neighborhood Search

    DEFF Research Database (Denmark)

    Pisinger, David; Røpke, Stefan

    2010-01-01

    Heuristics based on large neighborhood search have recently shown outstanding results in solving various transportation and scheduling problems. Large neighborhood search methods explore a complex neighborhood by use of heuristics. Using large neighborhoods makes it possible to find better...... candidate solutions in each iteration and hence traverse a more promising search path. Starting from the large neighborhood search method,we give an overview of very large scale neighborhood search methods and discuss recent variants and extensions like variable depth search and adaptive large neighborhood...... search....

  11. Myanmar Language Search Engine

    OpenAIRE

    Pann Yu Mon; Yoshiki Mikami

    2011-01-01

    With the enormous growth of the World Wide Web, search engines play a critical role in retrieving information from the borderless Web. Although many search engines are available for the major languages, but they are not much proficient for the less computerized languages including Myanmar. The main reason is that those search engines are not considering the specific features of those languages. A search engine which capable of searching the Web documents written in those languages is highly n...

  12. Bioinformatics: searching the Net.

    Science.gov (United States)

    Kastin, S; Wexler, J

    1998-04-01

    During the past 30 years, there has been an explosion in the volume of published medical information. As this volume has increased, so has the need for efficient methods for searching the data. MEDLINE, the primary medical database, is currently limited to abstracts of the medical literature. MEDLINE searches use AND/OR/NOT logical searching for keywords that have been assigned to each article and for textwords included in article abstracts. Recently, the complete text of some scientific journals, including figures and tables, has become accessible electronically. Keyword and textword searches can provide an overwhelming number of results. Search engines that use phrase searching, or searches that limit the number of words between two finds, improve the precision of search engines. The development of the Internet as a vehicle for worldwide communication, and the emergence of the World Wide Web (WWW) as a common vehicle for communication have made instantaneous access to much of the entire body of medical information an exciting possibility. There is more than one way to search the WWW for information. At the present time, two broad strategies have emerged for cataloging the WWW: directories and search engines. These allow more efficient searching of the WWW. Directories catalog WWW information by creating categories and subcategories of information and then publishing pointers to information within the category listings. Directories are analogous to yellow pages of the phone book. Search engines make no attempt to categorize information. They automatically scour the WWW looking for words and then automatically create an index of those words. When a specific search engine is used, its index is searched for a particular word. Usually, search engines are nonspecific and produce voluminous results. Use of AND/OR/NOT and "near" and "adjacent" search refinements greatly improve the results of a search. Search engines that limit their scope to specific sites, and

  13. [Impact of prepregnancy body mass index on pregnancy outcome in women with a singleton conceived by assisted reproductive technology and spontaneously conceived pregnancy: a case-control study].

    Science.gov (United States)

    Kim, Ju Hee; Shin, Hye Sook; Park, Bo Kyung; Yang, Kwang Moon; Lee, Young Ho; Ryu, Hyun Mee

    2012-08-01

    To compare and confirm the impact of prepregnancy body mass index on pregnancy outcome in women with a singleton conceived by assisted reproductive technology and spontaneously conceived pregnancy. A sample of 165 and 247 pregnant women with and without assisted reproductive technology were retrospectively recruited from electronic medical charts of C hospital. There were significant differences between the two groups for maternal age, paternal age, length of marriage, prepregnancy body mass index, parity, spontaneous abortion experience, and preterm delivery. A prepregnancy body mass index of ≥25 was associated with higher risk for maternal and neonatal complication in the assisted reproductive technology group. The results indicate that a higher prepregnancy body mass index is associated with increased risks for adverse pregnancy outcomes for women using assisted reproductive technology. So these women need appropriate care to compensate for the risk.

  14. Elemental content of the placenta: A comparison between two high-risk obstetrical populations, adult women carrying multiples and adolescents carrying singletons.

    Science.gov (United States)

    de Angelis, Paolo; Miller, Richard K; Darrah, Thomas H; Katzman, Philip J; Pressman, Eva K; Kent, Tera R; O'Brien, Kimberly O

    2017-10-01

    The placenta is responsible for the exchange of nutrients and for preventing harmful compounds from entering the fetal circulation. With increasing industrialization, exposures to commercial and toxic metals become a concern for both pregnant women and those planning a pregnancy. The understanding of transport mechanisms and pharmacokinetics for most inorganic elements is incomplete and limited to normal term deliveries. To obtain novel data on 46 inorganic elements in placentae from two high-risk obstetric populations, women carrying multiples and adolescents carrying singletons, evaluating differences, if present, and identifying predictors of placental content. Placental tissue was collected from adolescents carrying singletons and adults carrying multiples. Elemental content was analyzed using inductively coupled plasma-mass spectrometry (ICP-MS). Multivariate regression and factor analyses were used. With the exception of Au and Pt, almost all placentae contained quantifiable concentrations of each element analyzed. All placentae contained the essential elements Ca, Fe, Mg, Se and Zn, which clustered together onto the same factor. Most elements were higher in placentae from women carrying multiples. Differences in placental content disappeared after adjusting for maternal age. Rare earth elements (REEs) clustered together and remained higher in the multiples even after adjusting for maternal age. Human placentae contain a wide range of elements, including REEs. Ranges differed considerably between cohorts. Elements with similar chemical properties, like REEs or nutritionally essential elements, clustered together. Maternal age, and therefore longer environmental exposure, was significantly associated with elevated element concentrations in the placenta. Placental concentrations of several metals that are known to be nutritionally essential (e.g., Fe, Ca, Mg, and Zn) did not differ significantly between cohorts, suggesting tight regulation, whereas

  15. To Search or Not to Search!

    Science.gov (United States)

    Taylor, J. Rodney

    Constitutional guarantees, as provided by the Bill of Rights, are enjoyed by all citizens. This principle applies no less to students with respect to their college or university domicile. Case law on this subject suggests that three questions must be answered to determine the reasonableness of residence searching: (1) by whom the search is…

  16. Reward and Attentional Control in Visual Search

    Science.gov (United States)

    Anderson, Brian A.; Wampler, Emma K.; Laurent, Patryk A.

    2015-01-01

    It has long been known that the control of attention in visual search depends both on voluntary, top-down deployment according to context-specific goals, and on involuntary, stimulus-driven capture based on the physical conspicuity of perceptual objects. Recent evidence suggests that pairing target stimuli with reward can modulate the voluntary deployment of attention, but there is little evidence that reward modulates the involuntary deployment of attention to task-irrelevant distractors. We report several experiments that investigate the role of reward learning on attentional control. Each experiment involved a training phase and a test phase. In the training phase, different colors were associated with different amounts of monetary reward. In the test phase, color was not task-relevant and participants searched for a shape singleton; in most experiments no reward was delivered in the test phase. We first show that attentional capture by physically salient distractors is magnified by a previous association with reward. In subsequent experiments we demonstrate that physically inconspicuous stimuli previously associated with reward capture attention persistently during extinction—even several days after training. Furthermore, vulnerability to attentional capture by high-value stimuli is negatively correlated across individuals with working memory capacity and positively correlated with trait impulsivity. An analysis of intertrial effects reveals that value-driven attentional capture is spatially specific. Finally, when reward is delivered at test contingent on the task-relevant shape feature, recent reward history modulates value-driven attentional capture by the irrelevant color feature. The influence of learned value on attention may provide a useful model of clinical syndromes characterized by similar failures of cognitive control, including addiction, attention-deficit/hyperactivity disorder, and obesity. PMID:23437631

  17. The Search Performance Evaluation and Prediction in Exploratory Search

    OpenAIRE

    LIU, FEI

    2016-01-01

    The exploratory search for complex search tasks requires an effective search behavior model to evaluate and predict user search performance. Few studies have investigated the relationship between user search behavior and search performance in exploratory search. This research adopts a mixed approach combining search system development, user search experiment, search query log analysis, and multivariate regression analysis to resolve the knowledge gap. Through this study, it is shown that expl...

  18. Cube search, revisited

    Science.gov (United States)

    Zhang, Xuetao; Huang, Jie; Yigit-Elliott, Serap; Rosenholtz, Ruth

    2015-01-01

    Observers can quickly search among shaded cubes for one lit from a unique direction. However, replace the cubes with similar 2-D patterns that do not appear to have a 3-D shape, and search difficulty increases. These results have challenged models of visual search and attention. We demonstrate that cube search displays differ from those with “equivalent” 2-D search items in terms of the informativeness of fairly low-level image statistics. This informativeness predicts peripheral discriminability of target-present from target-absent patches, which in turn predicts visual search performance, across a wide range of conditions. Comparing model performance on a number of classic search tasks, cube search does not appear unexpectedly easy. Easy cube search, per se, does not provide evidence for preattentive computation of 3-D scene properties. However, search asymmetries derived from rotating and/or flipping the cube search displays cannot be explained by the information in our current set of image statistics. This may merely suggest a need to modify the model's set of 2-D image statistics. Alternatively, it may be difficult cube search that provides evidence for preattentive computation of 3-D scene properties. By attributing 2-D luminance variations to a shaded 3-D shape, 3-D scene understanding may slow search for 2-D features of the target. PMID:25780063

  19. Integrated vs. Federated Search

    DEFF Research Database (Denmark)

    Løvschall, Kasper

    2009-01-01

    Oplæg om forskelle og ligheder mellem integrated og federated search i bibliotekskontekst. Holdt ved temadag om "Integrated Search - samsøgning i alle kilder" på Danmarks Biblioteksskole den 22. januar 2009.......Oplæg om forskelle og ligheder mellem integrated og federated search i bibliotekskontekst. Holdt ved temadag om "Integrated Search - samsøgning i alle kilder" på Danmarks Biblioteksskole den 22. januar 2009....

  20. The Information Search

    Science.gov (United States)

    Doraiswamy, Uma

    2011-01-01

    This paper in the form of story discusses a college student's information search process. In this story we see Kuhlthau's information search process: initiation, selection, exploration, formulation, collection, and presentation. Katie is a student who goes in search of information for her class research paper. Katie's class readings, her interest…

  1. Risk of placenta praevia is linked to endometrial thickness in a retrospective cohort study of 4537 singleton assisted reproduction technology births.

    Science.gov (United States)

    Rombauts, L; Motteram, C; Berkowitz, E; Fernando, S

    2014-12-01

    Is endometrial thickness measured prior to embryo transfer associated with placenta praevia? Following IVF, the risk of placenta praevia is increased 4-fold in women with an endometrial thickness of >12 mm compared with women with an endometrial thickness of women who had 4537 singleton assisted reproduction technology (ART) births occurring between January 2006 and June 2012 with no loss to follow-up. The primary outcome measure was the diagnosis of placenta praevia, made by the treating obstetrician on a transvaginal ultrasound in the third trimester. Women who had singleton births following single embryo transfer performed at Monash IVF in Melbourne, Australia were included. Of the 4537 cycles leading to a singleton ART birth, 2951 were stimulated cycles with fresh embryo transfers; 355 were hormone replacement therapy frozen embryo transfers and 1231 were natural cycles with frozen embryo transfers. The dataset was analysed using binary logistic general estimating equations to calculate odds ratios for placenta praevia adjusted (aOR) for known confounders. The study groups did not differ significantly in age, BMI and aetiologies of infertility prior to IVF treatment. When compared with stimulated cycles, placenta praevia was less common in women undergoing natural cycles with frozen embryo transfers (OR 0.44, 95% confidence interval (CI) 0.27-0.70, P women with an endometrial thickness of women with an endometrial thickness of 9-12 mm had an aOR of 2.02 (95% CI 1.12-3.65, P = 0.02) and women with an endometrial thickness >12 mm had an aOR of 3.74 (95% CI 1.90-7.34, P women with no previous births. The study is retrospective in nature, not all confounders may have been accounted for and details on previous intrauterine surgery, a known risk factor, were not available. In addition, ultrasound assessments were carried out by several highly trained operators measuring the endometrial thickness, the main independent variable, in a two-dimensional plane and some

  2. Keyword Search in Databases

    CERN Document Server

    Yu, Jeffrey Xu; Chang, Lijun

    2009-01-01

    It has become highly desirable to provide users with flexible ways to query/search information over databases as simple as keyword search like Google search. This book surveys the recent developments on keyword search over databases, and focuses on finding structural information among objects in a database using a set of keywords. Such structural information to be returned can be either trees or subgraphs representing how the objects, that contain the required keywords, are interconnected in a relational database or in an XML database. The structural keyword search is completely different from

  3. The effects of embryo culture media on the birthweight of singletons via fresh or frozen-thawed embryo transfer: a large-scale retrospective study.

    Science.gov (United States)

    Gu, Fang; Deng, Mingfen; Gao, Jun; Wang, Zilian; Ding, Chenhui; Xu, Yanwen; Zhou, Canquan

    2016-09-19

    Embryo culture media used for IVF treatment might affect fetal growth and thus birthweight of the newborns. A retrospective study was conducted in South China using data from 2370 singleton neonates born after IVF/ICSI between 2009 and 2012. Two culture media, i.e., either Vitrolife or SAGE were used as embryo culture media during the study period. Neonates' birthweights were compared between the two embryo culture media groups. Among the 2370 singletons, 1755 cases came from fresh cleavage embryo transfer while 615 were from frozen-thawed cleavage embryo transfer. Within the fresh embryo transfer newborns, no statistical difference was observed in either birthweight (mean ± SD: 3196.0 ± 468.9 versus 3168.4 ± 462.0g, p > 0.05) or adjusted birthweight controlled for gestational age and gender (z-score mean ± SD: 0.11 ± 1.02 versus 0.11 ± 0.99 g, P > 0.05) between the Vitrolife (n = 419) and the SAGE group (n = 1336). Likewise within frozen embryo transfer neotates, no statistical difference of the birthweight (3300.6 ± 441.3 vs.3256.0 ± 466.7 g, P > 0.05) and adjusted birthweight (0.30 ± 0.99 g versus 0.29 ± 0.97 g, P > 0.05) was found between the Vitrolife (n = 202) and the SAGE group (n = 413). The sex ratio [OR1.17, 95 % CI (0.94-1.46)/OR1.1, 95 % CI (0.78-1.54)], rate of small for gestational age [OR1.14, 95 % CI (0.82-1.59)/OR1.06, 95 % CI (0.56-2.02)] and large for gestational age [OR1.07, 95 % CI (0.64-1.76)/OR0.98, 95 % CI (0.47-2.02)] in fresh and frozen-thawed subgourps are all comparable respectively between the two culture media. No group differences were found in the rate of low birthweight and macosomia. Multiple linear regression analysis demonstrated that maternal weight, gestational age, frozen-thawed embryo transfer and infant gender were significantly related to neonatal birthweight (P cultured in SAGE or Vitrolife media after fresh or frozen-thawed cleavage

  4. Effect of Smoking Behavior before and during Pregnancy on Selected Birth Outcomes among Singleton Full-Term Pregnancy: A Murmansk County Birth Registry Study.

    Science.gov (United States)

    Kharkova, Olga A; Grjibovski, Andrej M; Krettek, Alexandra; Nieboer, Evert; Odland, Jon Ø

    2017-08-02

    The aim of our study was to assess associations between smoking behavior before and during pregnancy and selected adverse birth outcomes. This study is based on the Murmansk County Birth Registry (MCBR). Our study includes women who delivered a singleton pregnancy after 37 weeks of gestation (N = 44,486). Smoking information was self-reported and assessed at the first antenatal visit during pregnancy. We adjusted for potential confounders using logistic regression. The highest proportion of infants with low values of birth weight, birth length, head circumference, ponderal index and of the Apgar score at 5 min was observed for women who smoked both before and during pregnancy. We observed a dose-response relationship between the number of cigarettes smoked per day during pregnancy and the odds of the aforementioned adverse birth outcomes; neither were there significant differences in their occurrences among non-smokers and those who smoked before but not during pregnancy. Moreover, smoking reduction during pregnancy relative to its pre-gestation level did not influence the odds of the adverse birth outcomes. Our findings emphasize a continued need for action against tobacco smoking during pregnancy.

  5. Perinatal Outcomes in Cephalic Compared With Noncephalic Singleton Presentation in the Setting of Preterm Premature Rupture of Membranes Before 32 Weeks of Gestation.

    Science.gov (United States)

    Yee, Lynn M; Grobman, William A

    2016-10-01

    To investigate the relationship between fetal presentation at the time of admission for preterm premature rupture of membranes (PROM) and perinatal outcomes, including gestational latency, among women in a large and well-characterized population with preterm PROM at less than 32 weeks of gestation. This was a secondary analysis of data from women randomized to receive magnesium sulfate compared with placebo in the previously reported Maternal-Fetal Medicine Units Network Beneficial Effects of Antenatal Magnesium Sulfate (1997-2004) trial. Women with a singleton gestation and preterm PROM were included. Fetal presentation at the time of randomization was recorded. Associations of fetal position (cephalic compared with noncephalic) with perinatal outcomes were compared using χ, Fisher exact, and Wilcoxon rank-sum tests. Perinatal outcomes included gestational latency, abruption, and neonatal morbidity and mortality. Multivariable regression (logistic, linear, and Cox) analyses were used to adjust for potential confounding factors. Of the 1,767 eligible women, 439 (24.5%) had a noncephalic presentation. Noncephalic presentation was associated with an earlier median gestational age at the time of preterm PROM (26.6 compared with 28.4 weeks of gestation, Ppreterm PROM are at greater risk of neonatal death.

  6. Singleton Sequence Type 382, an Emerging Clonal Group of Listeria monocytogenes Associated with Three Multistate Outbreaks Linked to Contaminated Stone Fruit, Caramel Apples, and Leafy Green Salad.

    Science.gov (United States)

    Chen, Yi; Luo, Yan; Pettengill, James; Timme, Ruth; Melka, David; Doyle, Matthew; Jackson, Alikeh; Parish, Mickey; Hammack, Thomas S; Allard, Marc W; Brown, Eric W; Strain, Errol A

    2017-03-01

    Three multistate outbreaks between 2014 and 2016, involving case patients in and outside the United States, were linked to stone fruit, caramel apples, and packaged leafy green salad contaminated with Listeria monocytogenes singleton sequence type 382 (ST382), a serotype IVb-v1 clone with limited genomic divergence. Isolates from these outbreaks and other ST382 isolates not associated with these outbreaks were analyzed by whole-genome sequencing (WGS) analysis. The primary differences among ST382 strains were single nucleotide polymorphisms (SNPs). WGS analysis differentiated ST382 from a clonal complex 1 outbreak strain co-contaminating the caramel apples. WGS clustered food, environmental, and clinical isolates within each outbreak, and also differentiated among the three outbreak strains and epidemiologically unrelated ST382 isolates, which were indistinguishable by pulsed-field gel electrophoresis. ST382 appeared to be an emerging clone that began to diverge from its ancestor approximately 32 years before 2016. We estimated that there was 1.29 nucleotide substitution per genome (2.94 Mbp) per year for this clone. Copyright © 2017 Chen et al.

  7. Outcomes following intra-amniotic instillation with indigo carmine to diagnose prelabor rupture of membranes in singleton pregnancies: a single center experience.

    Science.gov (United States)

    Adekola, Henry; Gill, Navleen; Sakr, Sharif; Hobson, Deslyn; Bryant, David; Abramowicz, Jacques S; Soto, Eleazar

    2016-01-01

    To evaluate clinical outcomes of women with singleton pregnancies that underwent intra-amniotic dye instillation (amniodye test) following equivocal diagnosis of prelabor rupture of membranes (PROM). Records of 34 pregnant women who underwent amniodye test for equivocal PROM were reviewed. Comparisons of characteristics, amniotic fluid (AF) cultures, AF interleukin (IL)-6 concentrations, and placenta pathology results between women who tested positive and those who tested negative were performed. A sub-analysis of women who were amniodye test-negative was also performed. (1) Commonest indication for amniodye test was a typical history of PROM with positive conventional tests and persistently normal AF volume, (2) amniodye test-positive women had a shorter procedure-to-delivery interval (p = 0.008), and a greater proportion of histologic acute chorioamnionitis (p = 0.04) and funisitis (p = 0.01) than amniodye-negative women, and (3) in addition to similarities to women with amniodye-positive test, amniodye test-negative women who delivered <34 weeks, had a greater proportion of women with risk for preterm birth (p = 0.04), than their counterparts who delivered between 34 0/7 and 36 6/7 weeks. Equivocal diagnosis of PPROM should warrant an amniodye test to avoid iatrogenic intervention in women with intact amniotic membranes. AF analysis should be performed in amniodye test-negative women.

  8. Adaptive Large Neighbourhood Search

    DEFF Research Database (Denmark)

    Røpke, Stefan

    Large neighborhood search is a metaheuristic that has gained popularity in recent years. The heuristic repeatedly moves from solution to solution by first partially destroying the solution and then repairing it. The best solution observed during this search is presented as the final solution....... This tutorial introduces the large neighborhood search metaheuristic and the variant adaptive large neighborhood search that dynamically tunes parameters of the heuristic while it is running. Both heuristics belong to a broader class of heuristics that are searching a solution space using very large...... neighborhoods. The tutorial also present applications of the adaptive large neighborhood search, mostly related to vehicle routing problems for which the heuristic has been extremely successful. We discuss how the heuristic can be parallelized and thereby take advantage of modern desktop computers...

  9. Search on Rugged Landscapes

    DEFF Research Database (Denmark)

    Billinger, Stephan; Stieglitz, Nils; Schumacher, Terry

    2014-01-01

    This paper presents findings from a laboratory experiment on human decision-making in a complex combinatorial task. We find strong evidence for a behavioral model of adaptive search. Success narrows down search to the neighborhood of the status quo, while failure promotes gradually more explorative...... search. Task complexity does not have a direct effect on behavior, but systematically affects the feedback conditions that guide success-induced exploitation and failure-induced exploration. The analysis also shows that human participants were prone to over-exploration, since they broke off the search...... for local improvements too early. We derive stylized decision rules that generate the search behavior observed in the experiment and discuss the implications of our findings for individual decision-making and organizational search....

  10. University Students' Online Information Searching Strategies in Different Search Contexts

    Science.gov (United States)

    Tsai, Meng-Jung; Liang, Jyh-Chong; Hou, Huei-Tse; Tsai, Chin-Chung

    2012-01-01

    This study investigates the role of search context played in university students' online information searching strategies. A total of 304 university students in Taiwan were surveyed with questionnaires in which two search contexts were defined as searching for learning, and searching for daily life information. Students' online search strategies…

  11. [Advanced online search techniques and dedicated search engines for physicians].

    Science.gov (United States)

    Nahum, Yoav

    2008-02-01

    In recent years search engines have become an essential tool in the work of physicians. This article will review advanced search techniques from the world of information specialists, as well as some advanced search engine operators that may help physicians improve their online search capabilities, and maximize the yield of their searches. This article also reviews popular dedicated scientific and biomedical literature search engines.

  12. Mobile Search and Advertising

    OpenAIRE

    Lovitskii, Vladimir; McCaffery, Colin; Thrasher, Michael; Traynor, David; Wright, Peter

    2009-01-01

    Mobile advertising is a rapidly growing sector providing brands and marketing agencies the opportunity to connect with consumers beyond traditional and digital media and instead communicate directly on their mobile phones. Mobile advertising will be intrinsically linked with mobile search, which has transported from the internet to the mobile and is identified as an area of potential growth. The result of mobile searching show that as a general rule such search result exceed 1...

  13. Mastering ElasticSearch

    CERN Document Server

    Kuc, Rafal

    2013-01-01

    A practical tutorial that covers the difficult design, implementation, and management of search solutions.Mastering ElasticSearch is aimed at to intermediate users who want to extend their knowledge about ElasticSearch. The topics that are described in the book are detailed, but we assume that you already know the basics, like the query DSL or data indexing. Advanced users will also find this book useful, as the examples are getting deep into the internals where it is needed.

  14. ElasticSearch cookbook

    CERN Document Server

    Paro, Alberto

    2013-01-01

    Written in an engaging, easy-to-follow style, the recipes will help you to extend the capabilities of ElasticSearch to manage your data effectively.If you are a developer who implements ElasticSearch in your web applications, manage data, or have decided to start using ElasticSearch, this book is ideal for you. This book assumes that you've got working knowledge of JSON and Java

  15. Google Power Search

    CERN Document Server

    Spencer, Stephan

    2011-01-01

    Behind Google's deceptively simple interface is immense power for both market and competitive research-if you know how to use it well. Sure, basic searches are easy, but complex searches require specialized skills. This concise book takes you through the full range of Google's powerful search-refinement features, so you can quickly find the specific information you need. Learn techniques ranging from simple Boolean logic to URL parameters and other advanced tools, and see how they're applied to real-world market research examples. Incorporate advanced search operators such as filetype:, intit

  16. Supersymmetry searches at CMS

    Directory of Open Access Journals (Sweden)

    Bargassa Pedrame

    2014-04-01

    Full Text Available The accumulation of 19 fb−1 of data at 8 TeV has been a unique window for Supersymmetry searches at the LHC, allowing the CMS collaboration to search for specific supersymmetric particles. This article covers the search for supersymmetric particles in a variety of production-and decay-modes as well as channels. It focuses on the search for the lightest scalar top (stop in the single lepton channel, stop which might be the only observable in the case where Supersymmetry is realized in nature, and which can play a unique role in “naturalness”

  17. Exotic Higgs searches

    CERN Document Server

    Pelliccioni, Mario

    2016-01-01

    Exotic Higgs searches cover a wide range of signatures, thus leading to indications to new physics beyond Standard Model. We report a review on exotic Higgs searches for lepton flavour violating Higgs decays, for "mono-Higgs" searches, for Higgs decays to invisible and for high mass Higgs searches. Both ATLAS and CMS results will be shown, for Run-1 data statistics collected at the energy of $\\sqrt s$ = 7,8 TeV and for the first data collected during Run-2 phase at the energy of $\\sqrt s$ = 13 TeV.

  18. Unstoppable, sbottomless sfermion searches

    Science.gov (United States)

    Trigger, Isabel

    Results are presented from searches by the LEP collaborations for scalar partners of leptons and light quarks in the context of the Minimal Supersymmetric Standard Model (MSSM). Examples shown are searches by OPAL for events with two leptons and significant missing transverse momentum and events with anomalous dE/dx, L3 searches for mass-degenerate squarks and for single electrons, and a DELPHI search for staus of mass less than MZ0/2. No evidence is observed for any signal indicating physics beyond the Standard Model (SM). Limits are shown in the context of a constrained MSSM (CMSSM).

  19. Unstoppable, bottomless sfermion searches

    Energy Technology Data Exchange (ETDEWEB)

    Trigger, Isabel [CERN (Switzerland)

    2004-07-01

    Results are presented from searches by the LEP collaborations for scalar partners of leptons and light quarks in the context of the Minimal Supersymmetric Standard Model (MSSM). Examples shown are searches by OPAL for events with two leptons and significant missing transverse momentum and events with anomalous dE/dx, L3 searches for mass-degenerate squarks and for single electrons, and a DELPHI search for staus of mass less than M{sub Z{sup 0/2}}. No evidence is observed for any signal indicating physics beyond the Standard Model (SM). Limits are shown in the context of a constrained MSSM (CMSSM). (orig.)

  20. Unstoppable, bottomless sfermion searches

    International Nuclear Information System (INIS)

    Trigger, Isabel

    2004-01-01

    Results are presented from searches by the LEP collaborations for scalar partners of leptons and light quarks in the context of the Minimal Supersymmetric Standard Model (MSSM). Examples shown are searches by OPAL for events with two leptons and significant missing transverse momentum and events with anomalous dE/dx, L3 searches for mass-degenerate squarks and for single electrons, and a DELPHI search for staus of mass less than M Z 0 /2. No evidence is observed for any signal indicating physics beyond the Standard Model (SM). Limits are shown in the context of a constrained MSSM (CMSSM). (orig.)

  1. Memory for found targets interferes with subsequent performance in multiple-target visual search.

    Science.gov (United States)

    Cain, Matthew S; Mitroff, Stephen R

    2013-10-01

    Multiple-target visual searches--when more than 1 target can appear in a given search display--are commonplace in radiology, airport security screening, and the military. Whereas 1 target is often found accurately, additional targets are more likely to be missed in multiple-target searches. To better understand this decrement in 2nd-target detection, here we examined 2 potential forms of interference that can arise from finding a 1st target: interference from the perceptual salience of the 1st target (a now highly relevant distractor in a known location) and interference from a newly created memory representation for the 1st target. Here, we found that removing found targets from the display or making them salient and easily segregated color singletons improved subsequent search accuracy. However, replacing found targets with random distractor items did not improve subsequent search accuracy. Removing and highlighting found targets likely reduced both a target's visual salience and its memory load, whereas replacing a target removed its visual salience but not its representation in memory. Collectively, the current experiments suggest that the working memory load of a found target has a larger effect on subsequent search accuracy than does its perceptual salience. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  2. Nonsequential search equilibrium with search cost heterogeneity

    NARCIS (Netherlands)

    Moraga-Gonzalez, Jose Luis; Sandor, Zsolt; Wildenbeest, Matthijs R.

    We generalize the model of Burdett and Judd (1983) to the case where an arbitrary finite number of firms sells a homogeneous good to buyers who have heterogeneous search costs. We show that a price dispersed symmetric Nash equilibrium always exists. Numerical results show that the behavior of prices

  3. Citation Searching: Search Smarter & Find More

    Science.gov (United States)

    Hammond, Chelsea C.; Brown, Stephanie Willen

    2008-01-01

    The staff at University of Connecticut are participating in Elsevier's Student Ambassador Program (SAmP) in which graduate students train their peers on "citation searching" research using Scopus and Web of Science, two tremendous citation databases. They are in the fourth semester of these training programs, and they are wildly successful: They…

  4. Agrosearch: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  5. Africa Development: Advanced Search

    African Journals Online (AJOL)

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  6. African Anthropologist: Advanced Search

    African Journals Online (AJOL)

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  7. Biokemistri: Advanced Search

    African Journals Online (AJOL)

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  8. Acta Structilia: Advanced Search

    African Journals Online (AJOL)

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  9. Measuring Online Search Expertise

    Science.gov (United States)

    Bailey, Earl

    2017-01-01

    Search expertise has long been studied and used extensively in information seeking behavior research, both as a fundamental concept and as a method of comparing groups of users. Unfortunately, while search expertise has been studied for some time, the conceptualization of it has lagged behind its use in categorizing users. This has led to users…

  10. Ergonomics SA: Advanced Search

    African Journals Online (AJOL)

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  11. Agronomie Africaine: Advanced Search

    African Journals Online (AJOL)

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  12. Mathematics Connection: Advanced Search

    African Journals Online (AJOL)

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  13. Critical Arts: Advanced Search

    African Journals Online (AJOL)

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  14. Rwanda Journal: Advanced Search

    African Journals Online (AJOL)

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  15. Kenya Veterinarian: Advanced Search

    African Journals Online (AJOL)

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  16. Supporting complex search tasks

    DEFF Research Database (Denmark)

    Gäde, Maria; Hall, Mark; Huurdeman, Hugo

    2015-01-01

    introductory to specialized, and from authoritative to speculative or opinionated, when to show what sources of information? How does the information seeking process evolve and what are relevant differences between different stages? With complex task and search process management, blending searching, browsing...

  17. Innovation: Advanced Search

    African Journals Online (AJOL)

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  18. Distributed Deep Web Search

    NARCIS (Netherlands)

    Tjin-Kam-Jet, Kien

    2013-01-01

    The World Wide Web contains billions of documents (and counting); hence, it is likely that some document will contain the answer or content you are searching for. While major search engines like Bing and Google often manage to return relevant results to your query, there are plenty of situations in

  19. Search and switching costs

    NARCIS (Netherlands)

    Siekman, Wilhelm Henricus

    2016-01-01

    This thesis analyses markets with search and with switching costs. It provides insights in several important issues in search markets, including how loss aversion may affect consumer behavior and firm conduct, and how prices, welfare, and profits may change when an intermediating platform orders

  20. Human memory search

    NARCIS (Netherlands)

    Davelaar, E.J.; Raaijmakers, J.G.W.; Hills, T.T.; Robbins, T.W.; Todd, P.M.

    2012-01-01

    The importance of understanding human memory search is hard to exaggerate: we build and live our lives based on what whe remember. This chapter explores the characteristics of memory search, with special emphasis on the use of retrieval cues. We introduce the dependent measures that are obtained

  1. ElasticSearch cookbook

    CERN Document Server

    Paro, Alberto

    2015-01-01

    If you are a developer who implements ElasticSearch in your web applications and want to sharpen your understanding of the core elements and applications, this is the book for you. It is assumed that you've got working knowledge of JSON and, if you want to extend ElasticSearch, of Java and related technologies.

  2. Annales Aequatoria: Advanced Search

    African Journals Online (AJOL)

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  3. Searching low and high

    DEFF Research Database (Denmark)

    Laursen, Keld; Salter, Ammon

    2003-01-01

    .The results suggest that firms who adopt `open' search strategies and invest in R&D are morelikely than other firms to draw from universities, indicating that managerial choice matters inshaping the propensity of firms to draw from universities.Key words: University-industry links, innovation, external search...

  4. Lexikos: Advanced Search

    African Journals Online (AJOL)

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  5. Kiswahili: Advanced Search

    African Journals Online (AJOL)

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  6. Philosophical Papers: Advanced Search

    African Journals Online (AJOL)

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  7. Sciences & Nature: Advanced Search

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  8. Counsellor (The): Advanced Search

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  9. Nigerian Libraries: Advanced Search

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  10. Vulture News: Advanced Search

    African Journals Online (AJOL)

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  11. Afrika Statistika: Advanced Search

    African Journals Online (AJOL)

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  12. Acta Theologica: Advanced Search

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  13. Water SA: Advanced Search

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  14. Tropical Veterinarian: Advanced Search

    African Journals Online (AJOL)

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  15. African Environment: Advanced Search

    African Journals Online (AJOL)

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  16. Zede Journal: Advanced Search

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  17. Africa Insight: Advanced Search

    African Journals Online (AJOL)

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  18. African Zoology: Advanced Search

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  19. Searches for Supersymmetry

    CERN Document Server

    Ventura, Andrea; The ATLAS collaboration

    2017-01-01

    New and recent results on Supersymmetry searches are shown for the ATLAS and the CMS experiments. Analyses with about 36 fb$^{-1}$ are considered for searches concerning light squarks and gluinos, direct pair production of 3$^{rd}$ generation squarks, electroweak production of charginos, neutralinos, sleptons, R-parity violating scenarios and long-lived particles.

  20. Search and Disrupt

    DEFF Research Database (Denmark)

    Ørding Olsen, Anders

    This paper analyzes how external search is affected by strategic interest alignment among knowledge sources. I focus on misalignment arising from the heterogeneous effects of disruptive technologies by analyzing the influence of incumbents on 2,855 non-incumbents? external knowledge search efforts....... The efforts most likely to solve innovation problems obtained funding from the European Commission?s 7th Framework Program (2007-2013). The results show that involving incumbents improves search in complementary technologies, while demoting it when strategic interests are misaligned in disruptive technologies....... However, incumbent sources engaged in capability reconfiguration to accommodate disruption improve search efforts in disruptive technologies. The paper concludes that the value of external sources is contingent on more than their knowledge. Specifically, interdependence of sources in search gives rise...

  1. Are risk factors for preterm and early-term live singleton birth the same? A population-based study in France.

    Science.gov (United States)

    Delnord, Marie; Blondel, Béatrice; Prunet, Caroline; Zeitlin, Jennifer

    2018-01-24

    To investigate whether risk factors for preterm (term birth (37 and 38 weeks gestation) are similar. Nationally representative cross-sectional study of births. France in 2010. Live singleton births (n=14 326). Preterm and early-term birth rates overall and by mode of delivery (spontaneous and indicated). Risk factors were maternal sociodemographic characteristics, previous preterm birth, height, prepregnancy body mass index (BMI) and smoking, assessed using multinomial regression models with full-term births 39 weeks and over as the reference group. There were 5.5% preterm and 22.5% early-term births. Common risk factors were: a previous preterm delivery (adjusted relative risk ratio (aRRR) 8.2 (95% CI 6.2 to 10.7) and aRRR 2.4 (95% CI 2.0 to 3.0), respectively), short stature, underweight (overall and in spontaneous deliveries), obesity (in indicated deliveries only), a low educational level and Sub-Saharan African origin. In contrast, primiparity was a risk factor only for preterm birth, aRRR 1.8 (95% CI 1.5 to 2.2), while higher parity was associated with greater risk of early-term birth. Most population-level risk factors were common to both preterm and early-term birth with the exception of primiparity, and BMI which differed by mode of onset of delivery. Our results suggest that preterm and early-term birth share similar aetiologies and thus potentially common strategies for prevention. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  2. Longitudinal growth of French singleton children born after in vitro fertilization and intracytoplasmic sperm injection. Body mass index up to 5 years of age.

    Science.gov (United States)

    Meddeb, L; Pauly, V; Boyer, P; Montjean, D; Devictor, B; Curel, L; Seng, P; Sambuc, R; Gervoise Boyer, M

    2017-06-01

    The literature presents conflicting results on the epigenetic effect of in vitro fertilization (IVF) on the short-term and mid-term growth of children. These contradictory results may be related to the use of heterogeneous methodologies and non-longitudinal data. The goal of this study was to compare the body mass index (BMI) of children conceived via IVF and spontaneous conception (SC) children, using longitudinal data from birth to 5 years. This study compared 118 singleton children born after in vitro fertilization, with or without intracytoplasmic sperm injection (ICSI), selected from a pre-existing single-center cohort to 320 SC children from the same geographic area. BMI and its evolution were analyzed using the mixed-effect model during three periods: before standing acquisition (from birth to 1 year of age), during standing acquisition, and the following period from 2 to 5 years of age. BMI means were not significantly different between groups regardless of the period, when adjusting for confounding factors related to parents, pregnancy, and children's characteristics and lifestyle. Nevertheless, during the standing acquisition period, children born after IVF-ICSI presented a less significant decrease in BMI (P<0.05). In addition, for each period we identified influencing factors (maternal BMI, level of wealth indicator) associated with BMI. In the study population, the suspected epigenetic influence of IVF reported in the literature was not observed for BMI from birth to 5 years of age. Further investigations need to be conducted to determine if the suspected influence of IVF on adiposity could be expressed through other parameters. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  3. Fear of childbirth in nulliparous and multiparous women: a population-based analysis of all singleton births in Finland in 1997-2010.

    Science.gov (United States)

    Räisänen, S; Lehto, S M; Nielsen, H S; Gissler, M; Kramer, M R; Heinonen, S

    2014-07-01

    To identify risk factors for fear of childbirth (FOC) according to parity and socioeconomic status, and to evaluate associations between FOC and adverse perinatal outcomes. A cohort study. The Finnish Medical Birth Register. All 788 317 singleton births during 1997-2010 in Finland. Fear of childbirth was defined according to the International Classification of Diseases code O99.80, and its associations with several risk factors and perinatal outcomes were analysed by multivariable logistic regression. Prevalence of, risk factors for and outcomes of FOC. Fear of childbirth was experienced by 2.5% of nulliparous women and 4.5% of multiparous women. The strongest risk factors for FOC in nulliparous women were depression [adjusted odds ratio (aOR), 6.35; 95% confidence interval (CI), 5.25-7.68], advanced maternal age (aOR, 3.78; 95% CI, 3.23-4.42) and high or unspecified socioeconomic status. In multiparous women, the strongest risk factors for FOC were depression (aOR, 5.47; 95% CI, 4.67-6.41), previous caesarean section (CS) (aOR, 3.02; 95% CI, 2.93-3.11) and high or unspecified socioeconomic status. Among both nulliparous and multiparous women, FOC was associated with higher rates of CS (3.3-fold and 4.5-fold higher, respectively) and a lower incidence of low birthweight (depression are predisposing factors for FOC regardless of parity. Among multiparous women, a previous CS increases vulnerability to FOC. FOC is associated with increased rates of CS, but does not adversely affect other pregnancy outcomes. © 2014 Royal College of Obstetricians and Gynaecologists.

  4. Preconception and prenatal urinary concentrations of phenols and birth size of singleton infants born to mothers and fathers from the Environment and Reproductive Health (EARTH) study.

    Science.gov (United States)

    Messerlian, Carmen; Mustieles, Vicente; Minguez-Alarcon, Lidia; Ford, Jennifer B; Calafat, Antonia M; Souter, Irene; Williams, Paige L; Hauser, Russ

    2018-02-22

    Although pregnancy concentrations of some phenols have been associated with infant size at birth, there is limited data on the effect of preconception exposure. We aimed to examine paternal and maternal preconception and maternal prenatal urinary phenol concentrations in relation to birth weight and head circumference. We evaluated 346 singletons born to 346 mothers and 184 fathers (184 couples) from a prospective preconception cohort of subfertile couples from the Environment and Reproductive Health (EARTH) Study in Boston, USA. We used multiple urine samples collected before the index pregnancy in both men and women to estimate mean preconception urinary benzophenone-3, triclosan, butylparaben, propylparaben, methylparaben, or ethylparaben concentrations. We also estimated mean maternal prenatal urinary phenol concentrations by averaging trimester-specific urine samples. Birth weight and head circumference were abstracted from delivery records. We estimated the association of natural log-phenol concentrations with birth outcomes using multivariable linear regression models, adjusting for known confounders. In adjusted models, each log-unit increase in paternal preconception benzophenone-3 concentration was associated with a 137 g increase in birth weight (95% CI: 60, 214). Additional adjustment for prenatal benzophenone-3 concentration strengthened this association. None of the maternal preconception phenol concentrations were associated with birth weight. However, maternal prenatal triclosan concentrations were associated with a 38 g decrease in birth weight (95% CI: -76, 0). Few associations were observed between phenols and head circumference except for a decrease of 0.27 cm (95% CI: -54, 0) in relation to maternal preconception methylparaben concentration. Although our findings should be interpreted in light of inherent study limitations, these results suggest potential evidence of associations between some paternal or maternal phenol concentrations and

  5. Prevalence of macrosomia and its risk factors in china: a multicentre survey based on birth data involving 101,723 singleton term infants.

    Science.gov (United States)

    Li, Guanghui; Kong, Lijun; Li, Zhiwen; Zhang, Li; Fan, Ling; Zou, Liying; Chen, Yi; Ruan, Yan; Wang, Xiaorong; Zhang, Weiyuan

    2014-07-01

    Macrosomia, defined as a birthweight at least 4000 g, is a public health problem because of its adverse influences on maternal and neonatal outcomes. Studies show that there is an increasing prevalence of macrosomia births in developing countries. However, information on the epidemiology of macrosomia is limited in China. This study aimed to determine the prevalence and geographic variability of macrosomia in China and risk factors that can be targeted for intervention. A hospital-based, cross-sectional survey was conducted in 14 provinces in China, covering a wide range of geographic areas. The medical records of 101,723 singleton term infants born in 39 hospitals during 2011 were reviewed. Multiple logistic regression analysis was used to examine the associations between demographic characteristics and the risk of macrosomia. The total prevalence of macrosomia was 7.3%. The prevalence varied between provinces, ranging from 4.1% to 13.4%. The prevalence of macrosomia in northern China (8.5%) was significantly higher than that in southern China (5.6%). Logistic regression analyses showed that risk of macrosomia was positively associated with maternal age, pre-pregnant body mass index (BMI), gravidity, parity, maternal height, gestational weight gain (GWG), gestational diabetes mellitus (GDM), and male fetal sex. Maternal BMI, gestational week, and GWG were the three risk factors most strongly associated with macrosomia. The prevalence of macrosomia varied dramatically between different areas of China. High pre-pregnancy BMI and GWG represent main modifiable risk factors for macrosomia and need more attention from health care providers. © 2014 John Wiley & Sons Ltd.

  6. Inter-pregnancy Weight Change and Risks of Severe Birth-Asphyxia-Related Outcomes in Singleton Infants Born at Term: A Nationwide Swedish Cohort Study.

    Science.gov (United States)

    Persson, Martina; Johansson, Stefan; Cnattingius, Sven

    2016-06-01

    Maternal overweight and obesity are associated with increased risks of birth-asphyxia-related outcomes, but the mechanisms are unclear. If a change of exposure (i.e., maternal body mass index [BMI]) over time influences risks, this would be consistent with a causal relationship between maternal BMI and offspring risks. Our objective was to investigate associations between changes in maternal BMI between consecutive pregnancies and risks of birth-asphyxia-related outcomes in the second offspring born at term. This study was a prospective population-based cohort study that included 526,435 second-born term (≥37 wk) infants of mothers with two consecutive live singleton term births in Sweden between January 1992 and December 2012. We estimated associations between the difference in maternal BMI between the first and second pregnancy and risks of low Apgar score (0-6) at 5 min, neonatal seizures, and meconium aspiration in the second-born offspring. Odds ratios (ORs) were adjusted for BMI at first pregnancy, maternal height, maternal age at second delivery, smoking, education, mother´s country of birth, inter-pregnancy interval, and year of second delivery. Analyses were also stratified by BMI (neonatal seizures, and meconium aspiration increased with inter-pregnancy weight gain. Compared with offspring of mothers with stable weight (BMI change of -1 to neonatal seizures and meconium aspiration were 1.42 (95% CI 1.00-2.02) and 1.78 (95% CI 1.19-2.68), respectively. The increased risk of neonatal seizures related to weight gain appeared to be restricted to mothers with BMI neonatal resuscitation efforts. Risks of birth-asphyxia-related outcomes increased with maternal weight gain between pregnancies. Preventing weight gain before and in between pregnancies may improve neonatal health.

  7. The Prevalence and Impact of Substance Use Disorder and Treatment on Maternal Obstetric Experiences and Birth Outcomes Among Singleton Deliveries in Massachusetts.

    Science.gov (United States)

    Kotelchuck, Milton; Cheng, Erika R; Belanoff, Candice; Cabral, Howard J; Babakhanlou-Chase, Hermik; Derrington, Taletha M; Diop, Hafsatou; Evans, Stephen R; Bernstein, Judith

    2017-04-01

    Objectives Despite widely-known negative effects of substance use disorders (SUD) on women, children, and society, knowledge about population-based prevalence and impact of SUD and SUD treatment during the perinatal period is limited. Methods Population-based data from 375,851 singleton deliveries in Massachusetts 2003-2007 were drawn from a maternal-infant longitudinally-linked statewide dataset of vital statistics, hospital discharges (including emergency department (ED) visits), and SUD treatment records. Maternal SUD and SUD treatment were identified from 1-year pre-conception through delivery. We determined (1) the prevalence of SUD and SUD treatment; (2) the association of SUD with women's perinatal health service utilization, obstetric experiences, and birth outcomes; and (3) the association of SUD treatment with birth outcomes, using both bivariate and adjusted analyses. Results 5.5% of Massachusetts's deliveries between 2003 and 2007 occurred in mothers with SUD, but only 66% of them received SUD treatment pre-delivery. Women with SUD were poorer, less educated and had more health problems; utilized less prenatal care but more antenatal ED visits and hospitalizations, and had worse obstetric and birth outcomes. In adjusted analyses, SUD was associated with higher risk of prematurity (AOR 1.35, 95% CI 1.28-1.41) and low birth weight (LBW) (AOR 1.73, 95% CI 1.64-1.82). Women receiving SUD treatment had lower odds of prematurity (AOR 0.61, 95% CI 0.55-0.68) and LBW (AOR 0.54, 95% CI 0.49-0.61). Conclusions for Practice SUD treatment may improve perinatal outcomes among pregnant women with SUD, but many who need treatment don't receive it. Longitudinally-linked existing public health and programmatic records provide opportunities for states to monitor SUD identification and treatment.

  8. Preventing preterm birth with progesterone: costs and effects of screening low risk women with a singleton pregnancy for short cervical length, the Triple P study

    Directory of Open Access Journals (Sweden)

    Duvekot Johannes J

    2011-10-01

    Full Text Available Abstract Background Women with a short cervical length in mid-trimester pregnancy have a higher risk of preterm birth and therefore a higher rate of neonatal mortality and morbidity. Progesterone can potentially decrease the number of preterm births and lower neonatal mortality and morbidity. Previous studies showed good results of progesterone in women with either a history of preterm birth or a short cervix. However, it is unknown whether screening for a short cervix and subsequent treatment in mid trimester pregnancy is effective in low risk women. Methods/Design We plan a combined screen and treat study among women with a singleton pregnancy without a previous preterm birth. In these women, we will measure cervical length at the standard anomaly scan performed between 18 and 22 weeks. Women with cervical length ≤ 30 mm at two independent measurements will be randomly allocated to receive either vaginal progesterone tablets or placebo between 22 and 34 weeks. The primary outcome of this trial is adverse neonatal condition, defined as a composite outcome of neonatal mortality and severe morbidity. Secondary outcomes are time to delivery, preterm birth rate before 32, 34 and 37 weeks, days of admission in neonatal intensive care unit, maternal morbidity, maternal admission days for preterm labour and costs. We will assess growth, physical condition and neurodevelopmental outcome of the children at two years of age. Discussion This study will provide evidence for the usefulness and cost-effectiveness of screening for short cervical length at the 18-22 weeks and subsequent progesterone treatment among low risk women. Trial registration Netherlands Trial Register (NTR: NTR207

  9. Backtrack Orbit Search Algorithm

    Science.gov (United States)

    Knowles, K.; Swick, R.

    2002-12-01

    A Mathematical Solution to a Mathematical Problem. With the dramatic increase in satellite-born sensor resolution traditional methods of spatially searching for orbital data have become inadequate. As data volumes increase end-users of the data have become increasingly intolerant of false positives. And, as computing power rapidly increases end-users have come to expect equally rapid search speeds. Meanwhile data archives have an interest in delivering the minimum amount of data that meets users' needs. This keeps their costs down and allows them to serve more users in a more timely manner. Many methods of spatial search for orbital data have been tried in the past and found wanting. The ever popular lat/lon bounding box on a flat Earth is highly inaccurate. Spatial search based on nominal "orbits" is somewhat more accurate at much higher implementation cost and slower performance. Spatial search of orbital data based on predict orbit models are very accurate at a much higher maintenance cost and slower performance. This poster describes the Backtrack Orbit Search Algorithm--an alternative spatial search method for orbital data. Backtrack has a degree of accuracy that rivals predict methods while being faster, less costly to implement, and less costly to maintain than other methods.

  10. Skewed Binary Search Trees

    DEFF Research Database (Denmark)

    Brodal, Gerth Stølting; Moruz, Gabriel

    2006-01-01

    It is well-known that to minimize the number of comparisons a binary search tree should be perfectly balanced. Previous work has shown that a dominating factor over the running time for a search is the number of cache faults performed, and that an appropriate memory layout of a binary search tree...... can reduce the number of cache faults by several hundred percent. Motivated by the fact that during a search branching to the left or right at a node does not necessarily have the same cost, e.g. because of branch prediction schemes, we in this paper study the class of skewed binary search trees....... For all nodes in a skewed binary search tree the ratio between the size of the left subtree and the size of the tree is a fixed constant (a ratio of 1/2 gives perfect balanced trees). In this paper we present an experimental study of various memory layouts of static skewed binary search trees, where each...

  11. How Users Search the Library from a Single Search Box

    Science.gov (United States)

    Lown, Cory; Sierra, Tito; Boyer, Josh

    2013-01-01

    Academic libraries are turning increasingly to unified search solutions to simplify search and discovery of library resources. Unfortunately, very little research has been published on library user search behavior in single search box environments. This study examines how users search a large public university library using a prominent, single…

  12. Entropy, Search, Complexity

    CERN Document Server

    Katona, Gyula O H; Tardos, Gábor

    2007-01-01

    The present volume is a collection of survey papers in the fields of entropy, search and complexity. They summarize the latest developments in their respective areas. More than half of the papers belong to search theory which lies on the borderline of mathematics and computer science, information theory and combinatorics, respectively. Search theory has variegated applications, among others in bioinformatics. Some of these papers also have links to linear statistics and communicational complexity. Further works survey the fundamentals of information theory and quantum source coding. The volume is recommended to experienced researchers as well as young scientists and students both in mathematics and computer science

  13. ElasticSearch server

    CERN Document Server

    Rogozinski, Marek

    2014-01-01

    This book is a detailed, practical, hands-on guide packed with real-life scenarios and examples which will show you how to implement an ElasticSearch search engine on your own websites.If you are a web developer or a user who wants to learn more about ElasticSearch, then this is the book for you. You do not need to know anything about ElastiSeach, Java, or Apache Lucene in order to use this book, though basic knowledge about databases and queries is required.

  14. Search for disappearing tracks

    CERN Document Server

    INSPIRE-00024550

    2015-01-01

    We present a search for long-lived charged particles that decay within the CMS detector and produce the signature of a disappearing track. Disappearing tracks are identified as those with little or no associated calorimeter energy deposits and with missing hits in the outer layers of the tracker. The search uses proton-proton collision data recorded at $\\sqrt{s} = 8$ TeV that corresponds to an integrated luminosity of 19.5 fb$^{-1}$. The results of the search are interpreted in the context of the anomaly-mediated supersymmetry breaking model and in terms of the phenomenological MSSM.

  15. Magnetic monopole search experiments

    International Nuclear Information System (INIS)

    Stone, J.L.

    1986-01-01

    Experimental searches for the elusive magnetic monopole have extended over 50 years -- ever since Dirac showed that the existence of isolated magnetic charges could account for the observation of quantized electric charge. Early searches for Dirac's monopole were hampered since there was no indication of the expected monopole mass, velocity, or origin in the theory. Consequently, numerous experiments searched more or less blindly for relativistic low mass monopoles in the cosmic rays and in particle collisions at high energy accelerators. In this paper, the author reviews briefly the monopole properties which are relevant for their detection and summarize current experimental efforts using induction, ionization/excitation, and catalysis techniques

  16. Exotic searches at lep

    International Nuclear Information System (INIS)

    Seager, P.

    2001-01-01

    The search for exotic processes at LEP is presented. The Standard Model Higgs has as yet not been observed. This provides freedom to search for processes beyond the Standard Model and even beyond the minimal version of the supersymmetric extension to the Standard Model. This paper outlines the searches for charged Higgs bosons, fermiophobic Higgs bosons, invisibly decaying Higgs bosons, technicolor, leptoquarks, unstable heavy leptons and excited leptons. The results presented are those from the LEP collaborations using data taken up to a centre-of-mass energy of √s = 202 GeV. (author)

  17. Modified harmony search

    Science.gov (United States)

    Mohamed, Najihah; Lutfi Amri Ramli, Ahmad; Majid, Ahmad Abd; Piah, Abd Rahni Mt

    2017-09-01

    A metaheuristic algorithm, called Harmony Search is quite highly applied in optimizing parameters in many areas. HS is a derivative-free real parameter optimization algorithm, and draws an inspiration from the musical improvisation process of searching for a perfect state of harmony. Propose in this paper Modified Harmony Search for solving optimization problems, which employs a concept from genetic algorithm method and particle swarm optimization for generating new solution vectors that enhances the performance of HS algorithm. The performances of MHS and HS are investigated on ten benchmark optimization problems in order to make a comparison to reflect the efficiency of the MHS in terms of final accuracy, convergence speed and robustness.

  18. Search and Disrupt

    DEFF Research Database (Denmark)

    Ørding Olsen, Anders

    Extant research on external knowledge search and open innovation assumes that collaborators are aligned in their strategic interests towards solving innovation problems. However, disruptive innovation is known to threaten the competitive advantage of incumbent firms, thereby creating a potential...

  19. Fuzzing and Vulnerabilities Search

    OpenAIRE

    Stanislav Evgenyevich Kirillov; Nikolai Petrovich Lavrentiev

    2013-01-01

    Fuzzing for vulnerabilities can be very effective if we know the input data format. This work contains description of network message format recovery algorithm and the usage of restored data model in fuzzing and vulnerabilities search.

  20. Fuzzing and Vulnerabilities Search

    Directory of Open Access Journals (Sweden)

    Stanislav Evgenyevich Kirillov

    2013-02-01

    Full Text Available Fuzzing for vulnerabilities can be very effective if we know the input data format. This work contains description of network message format recovery algorithm and the usage of restored data model in fuzzing and vulnerabilities search.

  1. Automated search for supernovae

    Energy Technology Data Exchange (ETDEWEB)

    Kare, J.T.

    1984-11-15

    This thesis describes the design, development, and testing of a search system for supernovae, based on the use of current computer and detector technology. This search uses a computer-controlled telescope and charge coupled device (CCD) detector to collect images of hundreds of galaxies per night of observation, and a dedicated minicomputer to process these images in real time. The system is now collecting test images of up to several hundred fields per night, with a sensitivity corresponding to a limiting magnitude (visual) of 17. At full speed and sensitivity, the search will examine some 6000 galaxies every three nights, with a limiting magnitude of 18 or fainter, yielding roughly two supernovae per week (assuming one supernova per galaxy per 50 years) at 5 to 50 percent of maximum light. An additional 500 nearby galaxies will be searched every night, to locate about 10 supernovae per year at one or two percent of maximum light, within hours of the initial explosion.

  2. Search and Recommendation

    DEFF Research Database (Denmark)

    Bogers, Toine

    2014-01-01

    In just a little over half a century, the field of information retrieval has experienced spectacular growth and success, with IR applications such as search engines becoming a billion-dollar industry in the past decades. Recommender systems have seen an even more meteoric rise to success with wide......-scale application by companies like Amazon, Facebook, and Netflix. But are search and recommendation really two different fields of research that address different problems with different sets of algorithms in papers published at distinct conferences? In my talk, I want to argue that search and recommendation...... are more similar than they have been treated in the past decade. By looking more closely at the tasks and problems that search and recommendation try to solve, at the algorithms used to solve these problems and at the way their performance is evaluated, I want to show that there is no clear black and white...

  3. Beyond the search process

    DEFF Research Database (Denmark)

    Hyldegård, Jette

    2009-01-01

    This paper reports on the findings from a longitudinal case study exploring Kuhlthau's information search process (ISP)-model in a group based academic setting. The research focus is on group members' activities and cognitive and emotional experiences during the task process of writing an assignm......This paper reports on the findings from a longitudinal case study exploring Kuhlthau's information search process (ISP)-model in a group based academic setting. The research focus is on group members' activities and cognitive and emotional experiences during the task process of writing...... seeking, the cognitive pattern associated with focus formulation and the tendency towards an increase in writing activities while searching activities decreased. Differences in behavior were also found, which were associated with contextual and social factors beyond the mere search process...

  4. Searches for supersymmetry

    International Nuclear Information System (INIS)

    Grivaz, J.F.

    1986-10-01

    Recent searches for supersymmetric particles, particularly in e + e - interactions, are reviewed and compared. The mass domains experimentally excluded are turned into limits on the supersymmetry breaking parameters of a minimal N=1 supergravity model

  5. Chemical Search Web Utility

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Chemical Search Web Utility is an intuitive web application that allows the public to easily find the chemical that they are interested in using, and which...

  6. Automated search for supernovae

    International Nuclear Information System (INIS)

    Kare, J.T.

    1984-01-01

    This thesis describes the design, development, and testing of a search system for supernovae, based on the use of current computer and detector technology. This search uses a computer-controlled telescope and charge coupled device (CCD) detector to collect images of hundreds of galaxies per night of observation, and a dedicated minicomputer to process these images in real time. The system is now collecting test images of up to several hundred fields per night, with a sensitivity corresponding to a limiting magnitude (visual) of 17. At full speed and sensitivity, the search will examine some 6000 galaxies every three nights, with a limiting magnitude of 18 or fainter, yielding roughly two supernovae per week (assuming one supernova per galaxy per 50 years) at 5 to 50 percent of maximum light. An additional 500 nearby galaxies will be searched every night, to locate about 10 supernovae per year at one or two percent of maximum light, within hours of the initial explosion

  7. Piled-Slab Searches

    National Research Council Canada - National Science Library

    Washburn, Alan

    2006-01-01

    This paper deals with the conflict between simplicity and optimality in searching for a stationary target whose location is distributed in two dimensions, thus continuing an analysis that was begun in World War II...

  8. Custom Search Engines: Tools & Tips

    Science.gov (United States)

    Notess, Greg R.

    2008-01-01

    Few have the resources to build a Google or Yahoo! from scratch. Yet anyone can build a search engine based on a subset of the large search engines' databases. Use Google Custom Search Engine or Yahoo! Search Builder or any of the other similar programs to create a vertical search engine targeting sites of interest to users. The basic steps to…

  9. Search for glueballs

    International Nuclear Information System (INIS)

    Toki, W.

    1997-01-01

    In these Summer School lectures, the author reviews the results of recent glueball searches. He begins with a brief review of glueball phenomenology and meson spectroscopy, including a discussion of resonance behavior. The results on the f o (1500) and f J (1700) resonances from proton-antiproton experiments and radiative J/Ψ decays are discussed. Finally, ππ and ηπ studies from D s decays and exotic meson searches are reviewed. 46 refs., 40 figs

  10. Scalable Automated Model Search

    Science.gov (United States)

    2014-05-20

    tributed learning environment. Specifically, how to best choose be- tween model families for supervised learning problems and config- ure the...io n Er ro r Maximum Calls 16 81 256 625 Comparison of Search Methods Across Learning Problems Figure 3: Search methods were compared across several...while several of the methods in this paper may apply to this setting, optimizing over this many hyperparameters for learning problems is not a well

  11. Searches for new physics

    International Nuclear Information System (INIS)

    Ellis, J.; Pauss, F.

    1989-01-01

    The CERN p bar p Collider has been the first accelerator to operate in a completely new energy domain, reaching center-of-mass energies an order of magnitude larger than those previously available with the intersecting Storage Rings (ISR) at CERN, or with the Positron-Electron Tandem Ring Accelerator (PETRA) at DESY and the Positron-Electron Project (PEP) at SLAC. Naturally there has been great interest in the searches for new physics in this virgin territory. Theorists have approached these searches from either or both of two rival points of view. Either they have had an a priori prejudice as to what new physics should be searched for, and what its signatures should be, or they have tried to interpret a posteriori some experimental observations. The basic building-blocks of new physics in the 100 GeV energy domain are jets j, charged leptons l, photons γ, and missing transverse energy E T . Therefore searches have been conducted in channels which are combinations of these elements. It also shows some of the main a priori theoretical prejudices which can be explored in each of these channels. The layout of the rest of this paper is as follows. There are sections discussing each of the major prejudices: the Standard Model supersymmetry; extra gauge degrees of freedom; composite models; and other possibilities. Each of these sections contains a description of the motivations and characteristics of the new physics to be searched for, followed by a review of the searches made up to now at the CERN p bar p Collider. Finally, it summarizes the lessons to be learnt so far from searches for new physics at the CERN p bar p Collider, and previews some of the prospects for the next rounds of collider searches at CERN and FNAL

  12. Status of gluonium searches

    International Nuclear Information System (INIS)

    Heusch, C.A.; California Univ., Santa Cruz, CA

    1991-01-01

    Quantum chromodynamics predicts the existence of quarkless mesons. The search for these hadrons has been ingenious and persevering. A review is presented of the current status of research that considers all model-dependent theoretical prejudice when searching for specific states. Early hints for candidate states have been investigated in the light of recent data, mostly from the Mark III Collaboration, in radiative charmonium decay. No 'smoking-gun' candidate stands out. (R.P.) 25 refs., 20 figs., 2 tabs

  13. Supersymmetry searches in ATLAS

    CERN Document Server

    Torro Pastor, Emma; The ATLAS collaboration

    2016-01-01

    Weak scale supersymmetry remains one of the best motivated and studied Standard Model extensions. This talk summarises recent ATLAS results for searches for supersymmetric (SUSY) particles. Weak and strong production in both R-Parity conserving and R-Parity violating SUSY scenarios are considered. The searches involved final states including jets, missing transverse momentum, light leptons, taus or photons, as well as long-lived particle signatures.

  14. Search and imperative programming

    OpenAIRE

    Apt, Krzysztof; Schaerf, A.

    1996-01-01

    textabstractWe augment the expressive power of imperative programming in order to make it a more attractive vehicle for problems that involve search.The proposed additions are limited yet powerful and are inspired by the logic programming paradigm.We illustrate their use by presenting solutions to a number of classical problems, including the straight search problem, the knapsack problem, and the 8 queens problem. These solutions are substantially simpler than their counterparts written in th...

  15. Supporting Book Search

    DEFF Research Database (Denmark)

    Bogers, Toine; Petras, Vivien

    2017-01-01

    Book search is far from a solved problem. Complex information needs often go beyond bibliographic facts and cover a combination of different aspects, such as specific genres or plot elements, engagement or novelty. Conventional book metadata may not be sufficient to address these kinds of informa......Book search is far from a solved problem. Complex information needs often go beyond bibliographic facts and cover a combination of different aspects, such as specific genres or plot elements, engagement or novelty. Conventional book metadata may not be sufficient to address these kinds...... of information needs. In this paper, we present a large-scale empirical comparison of the effectiveness of book metadata elements for searching complex information needs. Using a test collection of over 2 million book records and over 330 real-world book search requests, we perform a highly controlled and in......-depth analysis of topical metadata, comparing controlled vocabularies with social tags. Tags perform better overall in this setting, but controlled vocabulary terms provide complementary information, which will improve a search. We analyze potential underlying factors that contribute to search performance...

  16. Search Tips: MedlinePlus

    Science.gov (United States)

    ... of this page: https://medlineplus.gov/searchtips.html Search Tips To use the sharing features on this page, please enable JavaScript. How do I search MedlinePlus? The search box appears at the top ...

  17. Axion Searches, Old and New

    CERN Multimedia

    CERN. Geneva

    2005-01-01

    Outline of the lecture: Constraints from laboratory searches and astrophysics, axion cosmology, the cavity detector of dark matter axions, solar axion searches, laser experiments, a telescope search, macroscopic forces mediated by axions.

  18. Searching for What I Want

    DEFF Research Database (Denmark)

    Liu, Fei; Xiao, Bo Sophia; Lim, Eric

    2016-01-01

    of anticipa-tory system as our theoretical foundation to articulate the relationships between two salient types of search controls, namely search anticipation and search efficiency. We empirically validate our re-search model by conducting a field survey with 77 university students on an online restaurant...... review website that is modelled after its actual counterpart and populated with real restaurant review data. Findings from this study suggest that both search determination control and search manipulation con-trol enhance search result anticipation, which in turn improves search efficiency. Theoretical...

  19. SEARCHES FOR SUPERSYMMETRY IN ATLAS

    CERN Document Server

    Xu, Da; The ATLAS collaboration

    2017-01-01

    A wide range of supersymmetric searches are presented. All searches are based on the proton- proton collision dataset collected by the ATLAS experiment during the 2015 and 2016 (before summer) run with a center-of-mass energy of 13 TeV, corresponding to an integrated lumi- nosity of 36.1 (36.7) fb-1. The searches are categorized into inclusive gluino and squark search, third generation search, electroweak search, prompt RPV search and long-lived par- ticle search. No evidence of new physics is observed. The results are intepreted in various models and expressed in terms of limits on the masses of new particles.

  20. Searching for Movies

    DEFF Research Database (Denmark)

    Bogers, Toine

    2015-01-01

    -item search, are important for movie selection practices. Other requests focus more on recommendation and feature many subjective relevance aspects, such as the tone of a movie or its intended audience. This suggests efficient access to movies is likely to require different information access paradigms......Despite a surge in popularity of work on casual leisure search, some leisure domains are still relatively underrepresented. Movies are good example of such a domain, which is peculiar given the popularity of movie-centered websites and discovery services such as IMDB, RottenTomatoes, and Netflix....... In this paper, we present an exploratory analysis of IMDB movie discussion threads that contain requests for movies to watch. Through emergent coding we produce a taxonomy of relevance aspects for movie search and selection. Our analysis shows that topical aspects, such as content, metadata, and known...

  1. Optimizing Persistent Random Searches

    Science.gov (United States)

    Tejedor, Vincent; Voituriez, Raphael; Bénichou, Olivier

    2012-02-01

    We consider a minimal model of persistent random searcher with a short range memory. We calculate exactly for such a searcher the mean first-passage time to a target in a bounded domain and find that it admits a nontrivial minimum as function of the persistence length. This reveals an optimal search strategy which differs markedly from the simple ballistic motion obtained in the case of Poisson distributed targets. Our results show that the distribution of targets plays a crucial role in the random search problem. In particular, in the biologically relevant cases of either a single target or regular patterns of targets, we find that, in strong contrast to repeated statements in the literature, persistent random walks with exponential distribution of excursion lengths can minimize the search time, and in that sense perform better than any Levy walk.

  2. SearchResultFinder: federated search made easy

    NARCIS (Netherlands)

    Trieschnigg, Rudolf Berend; Tjin-Kam-Jet, Kien; Hiemstra, Djoerd

    Building a federated search engine based on a large number existing web search engines is a challenge: implementing the programming interface (API) for each search engine is an exacting and time-consuming job. In this demonstration we present SearchResultFinder, a browser plugin which speeds up

  3. Market Dominance and Search Quality in the Search Engine Market

    NARCIS (Netherlands)

    Lianos, I.; Motchenkova, E.I.

    2013-01-01

    We analyze a search engine market from a law and economics perspective and incorporate the choice of quality-improving innovations by a search engine platform in a two-sided model of Internet search engine. In the proposed framework, we first discuss the legal issues the search engine market raises

  4. Search for glueballs

    Energy Technology Data Exchange (ETDEWEB)

    Toki, W. [Colorado State Univ., Ft. Collins, CO (United States). Dept. of Physics

    1997-06-01

    In these Summer School lectures, the author reviews the results of recent glueball searches. He begins with a brief review of glueball phenomenology and meson spectroscopy, including a discussion of resonance behavior. The results on the f{sub o}(1500) and f{sub J}(1700) resonances from proton-antiproton experiments and radiative J/{Psi} decays are discussed. Finally, {pi}{pi} and {eta}{pi} studies from D{sub s} decays and exotic meson searches are reviewed. 46 refs., 40 figs.

  5. Quark search conference

    International Nuclear Information System (INIS)

    Anon.

    1981-01-01

    In spite of (or perhaps because of) the present doctrine of total quark confinement held by the majority of particle theorists, experimental searches for free fractional charge and other anomalous stable particles in ordinary matter have been increasing in number during recent years, using a range of techniques of increasing sophistication and sensitivity. As a result, researchers in this area had a conference to themselves in June. About 40 participants and 150 observers gathered at San Francisco State University to report progress and discuss future plans, with representatives present from almost every group involved in quark searches

  6. SUSY Searches at ATLAS

    CERN Document Server

    Mamuzic, Judita; The ATLAS collaboration

    2017-01-01

    Supersymmetry (SUSY) is considered one of the best motivated extensions of the Standard Model. It postulates a fundamental symmetry between fermions and bosons, and introduces a set of new supersymmetric particles at the electroweak scale. It addresses the hierarchy and naturalness problem, gives a solution to the gauge coupling unification, and offers a cold dark matter candidate. Different aspects of SUSY searches, using strong, electroweak, third generation production, and R-parity violation and long lived particles are being studied at the LHC. An overview of most recent SUSY searches results using the 13 TeV ATLAS RUN2 data will be presented.

  7. Upgrading Enterprise Search

    Energy Technology Data Exchange (ETDEWEB)

    McDunn, R

    2005-04-28

    This presentation will describe the process we went through this past year to upgrade our enterprise search tool from a very old version of Inktomi to the latest version of Verity Ultraseek. We started with requirements gathering and then compared requirements against several available products to determine which product to choose. After purchasing the product, we worked through several defined phases of implementation and customization, with initial rollout late January 2004. Finally, we will show you where we are today and describe future search plans.

  8. Searching with iterated maps.

    Science.gov (United States)

    Elser, V; Rankenburg, I; Thibault, P

    2007-01-09

    In many problems that require extensive searching, the solution can be described as satisfying two competing constraints, where satisfying each independently does not pose a challenge. As an alternative to tree-based and stochastic searching, for these problems we propose using an iterated map built from the projections to the two constraint sets. Algorithms of this kind have been the method of choice in a large variety of signal-processing applications; we show here that the scope of these algorithms is surprisingly broad, with applications as diverse as protein folding and Sudoku.

  9. Mastering Search Analytics Measuring SEO, SEM and Site Search

    CERN Document Server

    Chaters, Brent

    2011-01-01

    Many companies still approach Search Engine Optimization (SEO) and paid search as separate initiatives. This in-depth guide shows you how to use these programs as part of a comprehensive strategy-not just to improve your site's search rankings, but to attract the right people and increase your conversion rate. Learn how to measure, test, analyze, and interpret all of your search data with a wide array of analytic tools. Gain the knowledge you need to determine the strategy's return on investment. Ideal for search specialists, webmasters, and search marketing managers, Mastering Search Analyt

  10. The Evolution of Web Searching.

    Science.gov (United States)

    Green, David

    2000-01-01

    Explores the interrelation between Web publishing and information retrieval technologies and lists new approaches to Web indexing and searching. Highlights include Web directories; search engines; portalisation; Internet service providers; browser providers; meta search engines; popularity based analysis; natural language searching; links-based…

  11. Self-learning search engines

    NARCIS (Netherlands)

    Schuth, A.

    2015-01-01

    How does a search engine such as Google know which search results to display? There are many competing algorithms that generate search results, but which one works best? We developed a new probabilistic method for quickly comparing large numbers of search algorithms by examining the results users

  12. SUSY Searches at the Tevatron

    Energy Technology Data Exchange (ETDEWEB)

    Zivkovic, L.

    2011-07-01

    In this article results from supersymmetry searches at D0 and CDF are reported. Searches for third generation squarks, searches for gauginos, and searches for models with R-parity violation are described. As no signs of supersymmetry for these models are observed, the most stringent limits to date are presented.

  13. Prices and heterogeneous search costs

    NARCIS (Netherlands)

    Luis Moraga-Gonzalez, Jose; Sandor, Zsolt; Wildenbeest, Matthijs R.

    2017-01-01

    We study price formation in a model of consumer search for differentiated products in which consumers have heterogeneous search costs. We provide conditions under which a pure-strategy symmetric Nash equilibrium exists and is unique. Search costs affect two margins-the intensive search margin (or

  14. Complete local search with memory

    NARCIS (Netherlands)

    Ghosh, D.; Sierksma, G.

    2000-01-01

    Neighborhood search heuristics like local search and its variants are some of the most popular approaches to solve discrete optimization problems of moderate to large size. Apart from tabu search, most of these heuristics are memoryless. In this paper we introduce a new neighborhood search heuristic

  15. Self-learning search engines

    NARCIS (Netherlands)

    Schuth, A.

    How does a search engine such as Google know which search results to display? There are many competing algorithms that generate search results, but which one works best? We developed a new probabilistic method for quickly comparing large numbers of search algorithms by examining the results users

  16. SUSY Search at LHC

    CERN Document Server

    Xu, Da; The ATLAS collaboration

    2018-01-01

    Despite the absence of experimental evidence, weak scale supersymmetry remains one of the best motivated and studied Standard Model extensions. This talk gives an overview of the most recent SUSY searches in ATLAS and CMS experiments using 13 TeV ATLAS Run2 data.

  17. The Pulsar Search Collaboratory

    Science.gov (United States)

    Rosen, R.; Heatherly, S.; McLaughlin, M. A.; Kondratiev, V. I.; Boyles, J. R.; Wilson, M.; Lorimer, D. R.; Lynch, R.; Ransom, S.

    2010-01-01

    The Pulsar Search Collaboratory (PSC) (NSF #0737641) is a joint project between the National Radio Astronomy Observatory and West Virginia University designed to interest high school students in science, technology, engineering, and mathematics related career paths by helping them to conduct authentic scientific research. The 3 year PSC program,…

  18. Internet video search

    NARCIS (Netherlands)

    Snoek, C.G.M.; Smeulders, A.W.M.

    2011-01-01

    In this tutorial, we focus on the challenges in internet video search, present methods how to achieve state-of-the-art performance while maintaining efficient execution, and indicate how to obtain improvements in the near future. Moreover, we give an overview of the latest developments and future

  19. Recursive Lexicographical Search

    DEFF Research Database (Denmark)

    Iskhakov, Fedor; Rust, John; Schjerning, Bertel

    2016-01-01

    which state recursion finds at least one MPE of the overall DDG and introduce a recursive lexicographic search (RLS) algorithm that systematically and efficiently uses state recursion to find all MPE of the overall game in a finite number of steps. We apply RLS to find all MPE of a dynamic model...

  20. Biased Predecessor Search

    DEFF Research Database (Denmark)

    Bose, Prosenjit; Fagerberg, Rolf; Howat, John

    2016-01-01

    We consider the problem of performing predecessor searches in a bounded universe while achieving query times that depend on the distribution of queries. We obtain several data structures with various properties: in particular, we give data structures that achieve expected query times logarithmic...