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Sample records for single-pulse experiments maximize

  1. A Single-Pulse Integrator

    DEFF Research Database (Denmark)

    Miller, Arne

    1974-01-01

    A single-pulse integrator is described. It gives a relative measure of the integral of the output signal from a coil monitor on the Risø 10 MeV linear accelerator, and displays the value on a digital voltmeter. The reproduccibility is found to be better than ±1% for an accelerated pulse charge...

  2. Maximizing Macromolecule Crystal Size for Neutron Diffraction Experiments

    Science.gov (United States)

    Judge, R. A.; Kephart, R.; Leardi, R.; Myles, D. A.; Snell, E. H.; vanderWoerd, M.; Curreri, Peter A. (Technical Monitor)

    2002-01-01

    A challenge in neutron diffraction experiments is growing large (greater than 1 cu mm) macromolecule crystals. In taking up this challenge we have used statistical experiment design techniques to quickly identify crystallization conditions under which the largest crystals grow. These techniques provide the maximum information for minimal experimental effort, allowing optimal screening of crystallization variables in a simple experimental matrix, using the minimum amount of sample. Analysis of the results quickly tells the investigator what conditions are the most important for the crystallization. These can then be used to maximize the crystallization results in terms of reducing crystal numbers and providing large crystals of suitable habit. We have used these techniques to grow large crystals of Glucose isomerase. Glucose isomerase is an industrial enzyme used extensively in the food industry for the conversion of glucose to fructose. The aim of this study is the elucidation of the enzymatic mechanism at the molecular level. The accurate determination of hydrogen positions, which is critical for this, is a requirement that neutron diffraction is uniquely suited for. Preliminary neutron diffraction experiments with these crystals conducted at the Institute Laue-Langevin (Grenoble, France) reveal diffraction to beyond 2.5 angstrom. Macromolecular crystal growth is a process involving many parameters, and statistical experimental design is naturally suited to this field. These techniques are sample independent and provide an experimental strategy to maximize crystal volume and habit for neutron diffraction studies.

  3. Single-pulse electrons from a linear accelerator

    International Nuclear Information System (INIS)

    Antoku, Shigetoshi; Sunayashiki, Tadashi; Takeoka, Seiji; Kato, Kazushi

    1976-01-01

    The electronic circuits of a 35 MeV linear accelerator at Hiroshima University were modified to produce single-pulse electrons. Single-pulse electrons were obtained by synchronizing one of eight pulses from an electron gun modulator, 120 pps, to one of the micro-waves from a klystron, 15 pps. After single-pulse electrons were discharged, a signal was relayed to a stop-gate circuit from a binary scaler which was connected to the gun modulator. Although reproducibility of single-pulse electrons and stability of electron output per pulse were not completely satisfactory, it was possible to use for radiobiological studies. Biological effects of single-pulse electrons (energy: 25 MeV, dose rate: 10 10 rad/min) on cultured mammalian cells and on mice were nearly equal to those of multi-pulse electrons (25 MeV, 10 7 rad/min) and Co-60 γ-rays (dose rate: 100 rad/min). (auth.)

  4. Methods for Maximizing Graduate Students’ Learning Experience: An Insider’s Perspective

    Directory of Open Access Journals (Sweden)

    Habsah Hussin

    2014-07-01

    Full Text Available Graduate students furthering their studies at Master level are mature adult learners who bring with them a myriad of educational backgrounds and professional experiences into their studies.  Delivering knowledge and information to them the traditional way via the lecture method per se may not be very effective anymore.  They need methods that can utilize and make relevant their existing knowledge and professional experiences to help them realize their full potentials.  This paper discusses the incorporation of four methods (individual presentation, dialogue, article critiquing and forum into a graduate-level course (ESL Methodology to supplement the lecture method, to provide variation in methods of teaching graduate students and as alternative measures for these graduate students to maximize their learning experience.

  5. Sequential Design of Experiments to Maximize Learning from Carbon Capture Pilot Plant Testing

    Energy Technology Data Exchange (ETDEWEB)

    Soepyan, Frits B.; Morgan, Joshua C.; Omell, Benjamin P.; Zamarripa-Perez, Miguel A.; Matuszewski, Michael S.; Miller, David C.

    2018-02-06

    Pilot plant test campaigns can be expensive and time-consuming. Therefore, it is of interest to maximize the amount of learning and the efficiency of the test campaign given the limited number of experiments that can be conducted. This work investigates the use of sequential design of experiments (SDOE) to overcome these challenges by demonstrating its usefulness for a recent solvent-based CO2 capture plant test campaign. Unlike traditional design of experiments methods, SDOE regularly uses information from ongoing experiments to determine the optimum locations in the design space for subsequent runs within the same experiment. However, there are challenges that need to be addressed, including reducing the high computational burden to efficiently update the model, and the need to incorporate the methodology into a computational tool. We address these challenges by applying SDOE in combination with a software tool, the Framework for Optimization, Quantification of Uncertainty and Surrogates (FOQUS) (Miller et al., 2014a, 2016, 2017). The results of applying SDOE on a pilot plant test campaign for CO2 capture suggests that relative to traditional design of experiments methods, SDOE can more effectively reduce the uncertainty of the model, thus decreasing technical risk. Future work includes integrating SDOE into FOQUS and using SDOE to support additional large-scale pilot plant test campaigns.

  6. Single Pulse Electrical Stimulation to identify epileptogenic cortex : Clinical information obtained from early evoked responses

    NARCIS (Netherlands)

    Mouthaan, B.E.; van 't Klooster, M.A.; Keizer, D.; Hebbink, G.J.; Leijten, F.S.S.; Ferrier, C.H.; van Putten, M.J.A.M.; Zijlmans, M.; Huiskamp, G.J.M.

    Objective: Single Pulse Electrical Stimulation (SPES) probes epileptogenic cortex during electrocorticography. Two SPES responses are described: pathological delayed responses (DR, >100 ms) associated with the seizure onset zone (SOZ) and physiological early responses (ER, <100 ms) that map cortical

  7. Maximizing the use of research reactors in training power reactor operating staff with special reference to US experience

    International Nuclear Information System (INIS)

    Cox, J.A.

    1976-01-01

    Research reactors have been used in training nuclear power plant personnel for many years. Using the experience in the United States of America a programme is proposed that will maximize the training conducted at a research reactor and lessen the time that the staff must spend training elsewhere. The programme is adaptable to future training of replacement staff and for staff retraining. (author)

  8. Catastrophic optical mirror damage in diode lasers monitored during single-pulse operation

    DEFF Research Database (Denmark)

    Zegler, M.; Tomm, J.W.; Reeber, D.

    2009-01-01

    Catastrophic optical mirror damage (COMD) is analyzed for 808 nm emitting diode lasers in single-pulse operation in order to separate facet degradation from subsequent degradation processes. During each pulse, nearfield and thermal images are monitored. A temporal resolution better than 7 µs...... is achieved. The thermal runaway process is unambiguously related to the occurrence of a “thermal flash.” A one-by-one correlation between nearfield, thermal flash, thermal runaway, and structural damage is observed. The single-pulse excitation technique allows for controlling the propagation...

  9. Wanting to Maximize the Positive and Minimize the Negative: Implications for Mixed Affective Experience in American and Chinese Contexts

    Science.gov (United States)

    Sims, Tamara; Tsai, Jeanne L.; Jiang, Da; Wang, Yaheng; Fung, Helene H.; Zhang, Xiulan

    2016-01-01

    Previous studies have demonstrated that European Americans have fewer mixed affective experiences (i.e., are less likely to experience the bad with the good) compared to Chinese. In this paper, we argue that these cultural differences are due to “ideal affect,” or how people ideally want to feel. Specifically, we predict that people from individualistic cultures want to maximize positive and minimize negative affect more than people from collectivistic cultures, and as a result, they are less likely to actually experience mixed emotions (reflected by a more negative within-person correlation between actual positive and negative affect). We find support for this prediction in two experience sampling studies conducted in the U.S. and China (Studies 1 and 2). In addition, we demonstrate that ideal affect is a distinct construct from dialectical view of the self, which has also been related to mixed affective experience (Study 3). Finally, in Study 4, we demonstrate that experimentally manipulating the desire to maximize the positive and minimize the negative alters participants' actual experience of mixed emotions during a pleasant (but not unpleasant or combined pleasant and unpleasant) television clip in the U.S. and Hong Kong. Together, these findings suggest that across cultures, how people want to feel shapes how they actually feel, particularly people's mixed affective experience. PMID:26121525

  10. Simulation investigation of thermal phase transformation and residual stress in single pulse EDM of Ti-6Al-4V

    Science.gov (United States)

    Tang, Jiajing; Yang, Xiaodong

    2018-04-01

    The thermal phase transformation and residual stress are ineluctable in the electrical discharge machining (EDM) process, and they will greatly affect the working performances of the machined surface. This paper presents a simulation study on the thermal phase transformation and residual stress in single-pulse EDM of Ti-6Al-4V, which is the most popular titanium alloy in fields such as aircraft engine and some other leading industries. A multi-physics model including thermal, hydraulic, metallography and structural mechanics was developed. Based on the proposed model, the thickness and metallographic structure of the recast layer and heat affected layer (HAZ) were investigated. The distribution and characteristics of residual stress around the discharge crater were obtained. The recast layer and HAZ at the center of crater are found to be the thinnest, and their thicknesses gradually increase approaching the periphery of the crater. The recast layer undergoes a complete α‧ (martensitic) transformation, while the HAZ is mainly composed by the α  +  β  +  α‧ three-phase microstructure. Along the depth direction of crater, the Von Mises stress increases first and then decreases, reaching its maximal value near the interface of recast layer and HAZ. In the recast layer, both compressive stress component and tensile stress component are observed. ANOVA results showed that the influence of discharge current on maximal tensile stress is more significant than that of pulse duration, while the pulse duration has more significant influence on average thickness of the recast layer and the depth location of the maximal tensile stress. The works conducted in this study will help to evaluate the quality and integrity of EDMed surface, especially when the non-destructive testing is difficult to achieve.

  11. Longitudinal approach to assessing maximal aerobic power during growth: the European experience.

    Science.gov (United States)

    Rutenfranz, J

    1986-06-01

    This review deals with the principle and constraints of conducting longitudinal studies on exercise in children. As with cross-sectional studies, longitudinal ones have advantages and constraints: the different types of such designs as mass studies, population studies, or prospective cohort studies should be therefore selected to minimize their possible drawbacks. Other problems of longitudinal studies, such as the age span studied, time and sequential measurement effects, or interventional effects, have to be controlled by statistical measures and study design. In longitudinal studies ad hoc research groups working in field laboratories are for many reasons more flexible than permanent teams using institutional laboratories. Only direct determinations of maximal aerobic power should be used in longitudinal studies. These should be accompanied by such measurements as body height, body mass, lean body mass, and peak height velocity and by such health indicators as daily physical activity, blood pressure, smoking habits, and blood lipids. Examples for this approach are given in this paper, and general issues of longitudinal studies are discussed from the economic and ethical point of view.

  12. Broadband single-pulse CARS spectra in a fired internal combustion engine.

    Science.gov (United States)

    Klick, D; Marko, K A; Rimai, L

    1981-04-01

    The first known broadband single-pulse coherent anti-Stokes Raman scattering (CARS) measurements within the cylinder of a firing internal combustion engine are reported. Postcombustion temperature and carbon monoxide concentration are probed with 1-mm(3) spatial resolution and 10-nsec temporal resolution. Space- and time-resolved measurements, as presented here, are shown to be necessary for the study of fluctuating systems such as engines.

  13. Maximizing Science Return from Future Rodent Experiments on the International Space Station (ISS): Tissue Preservation

    Science.gov (United States)

    Choi, S. Y.; Lai, S.; Klotz, R.; Popova, Y.; Chakravarty, K.; Beegle, J. E.; Wigley, C. L.; Globus, R. K.

    2014-01-01

    To better understand how mammals adapt to long duration habitation in space, a system for performing rodent experiments on the ISS is under development; Rodent Research-1 is the first flight and will include validation of both on-orbit animal support and tissue preservation. To evaluate plans for on-orbit sample dissection and preservation, we simulated conditions for euthanasia, tissue dissection, and prolonged sample storage on the ISS, and we also developed methods for post-flight dissection and recovery of high quality RNA from multiple tissues following prolonged storage in situ for future science. Mouse livers and spleens were harvested under conditions that simulated nominal, on-orbit euthanasia and dissection operations including storage at -80 C for 4 months. The RNA recovered was of high quality (RNA Integrity Number, RIN(is) greater than 8) and quantity, and the liver enzyme contents and activities (catalase, glutathione reductase, GAPDH) were similar to positive controls, which were collected under standard laboratory conditions. We also assessed the impact of possible delayed on-orbit dissection scenarios (off-nominal) by dissecting and preserving the spleen (RNAlater) and liver (fast-freezing) at various time points post-euthanasia (from 5 min up to 105 min). The RNA recovered was of high quality (spleen, RIN (is) greater than 8; liver, RIN (is) greater than 6) and liver enzyme activities were similar to positive controls at all time points, although an apparent decline in select enzyme activities was evident at the latest time (105 min). Additionally, various tissues were harvested from either intact or partially dissected, frozen carcasses after storage for approximately 2 months; most of the tissues (brain, heart, kidney, eye, adrenal glands and muscle) were of acceptable RNA quality for science return, whereas some tissues (small intestine, bone marrow and bones) were not. These data demonstrate: 1) The protocols developed for future flight

  14. Maximizing Undergraduate Success By Combining Research Experiences with Outreach, Peer Mentoring and Professional Development

    Science.gov (United States)

    Bruno, B. C.

    2014-12-01

    The C-MORE Scholars Program provides hands-on, closely mentored research experiences to University of Hawaii (UH) undergraduates during the academic year. Students majoring in the geosciences, especially underrepresented students, from all campuses are encouraged to apply. The academic-year research is complemented by outreach, professional development and summer internships. Combined, these experiences help students develop the skills, confidence and passion that are essential to success in a geoscience career. Research. All students enter the program as trainees, where they learn lab and field research methods, computer skills and science principles. After one year, they are encouraged to reapply as interns, where they work on their own research project. Students who have successfully completed their intern year can reapply as fellows, where they conduct an independent research project such as an honors thesis. Students present their research at a Symposium through posters (trainees) or talks (interns and fellows). Interns and fellows help organize program activities and serve as peer mentors to trainees.Multi-tiered programs that build a pathway toward graduation have been shown to increase student retention and graduation success. Outreach. Undergraduate researchers rarely feel like experts when working with graduate students and faculty. For students to develop their identity as scientists, it is essential that they be given the opportunity to assume the role as expert. Engaging students in outreach is a win-win situation. Students gain valuable skills and confidence in sharing their research with their local community, and the public gets to learn about exciting research happening at UH. Professional Development. Each month, the Scholars meet to develop their professional skills on a particular topic, such as outreach, scientific presentations, interviewing, networking, and preparing application materials for jobs, scholarships and summer REUs. Students are

  15. Adaptive Measurement of Well-Being: Maximizing Efficiency and Optimizing User Experience during Individual Assessment.

    Science.gov (United States)

    Kraatz, Miriam; Sears, Lindsay E; Coberley, Carter R; Pope, James E

    2016-08-01

    Well-being is linked to important societal factors such as health care costs and productivity and has experienced a surge in development activity of both theories and measurement. This study builds on validation of the Well-Being 5 survey and for the first time applies Item Response Theory, a modern and flexible measurement paradigm, to form the basis of adaptive population well-being measurement. Adaptive testing allows survey questions to be administered selectively, thereby reducing the number of questions required of the participant. After the graded response model was fit to a sample of size N = 12,035, theta scores were estimated based on both the full-item bank and a simulation of Computerized Adaptive Testing (CAT). Comparisons of these 2 sets of score estimates with each other and of their correlations with external outcomes of job performance, absenteeism, and hospital admissions demonstrate that the CAT well-being scores maintain accuracy and validity. The simulation indicates that the average survey taker can expect a reduction in number of items administered during the CAT process of almost 50%. An increase in efficiency of this extent is of considerable value because of the time savings during the administration of the survey and the potential improvement of user experience, which in turn can help secure the success of a total population-based well-being improvement program. (Population Health Management 2016;19:284-290).

  16. Maximal ? -regularity

    NARCIS (Netherlands)

    Van Neerven, J.M.A.M.; Veraar, M.C.; Weis, L.

    2015-01-01

    In this paper, we prove maximal regularity estimates in “square function spaces” which are commonly used in harmonic analysis, spectral theory, and stochastic analysis. In particular, they lead to a new class of maximal regularity results for both deterministic and stochastic equations in L p

  17. Entropy maximization

    Indian Academy of Sciences (India)

    It is shown that (i) every probability density is the unique maximizer of relative entropy in an appropriate class and (ii) in the class of all pdf that satisfy ∫ f h i d = i for i = 1 , 2 , … , … k the maximizer of entropy is an f 0 that is proportional to exp ⁡ ( ∑ c i h i ) for some choice of c i . An extension of this to a continuum of ...

  18. Maximal balleans

    Directory of Open Access Journals (Sweden)

    Olga I. Protasova

    2006-10-01

    Full Text Available A ballean is a set X endowed with some family of subsets of X which are called the balls. We postulate the properties of the family of balls in such a way that the balleans with the appropriate morphisms can be considered as the asymptotic counterparts of the uniform topological spaces. The purpose of the paper is to find and study the asymptotic counterparts for maximal topological spaces and maximal topological groups.

  19. Entropy Maximization

    Indian Academy of Sciences (India)

    It is shown that (i) every probability density is the unique maximizer of relative entropy in an appropriate class and (ii) in the class of all pdf that satisfy ∫ f h i d = i for i = 1 , 2 , … , … k the maximizer of entropy is an f 0 that is proportional to exp ⁡ ( ∑ c i h i ) for some choice of c i . An extension of this to a continuum of ...

  20. Entropy maximization

    Indian Academy of Sciences (India)

    Abstract. It is shown that (i) every probability density is the unique maximizer of relative entropy in an appropriate class and (ii) in the class of all pdf f that satisfy. ∫ fhi dμ = λi for i = 1, 2,...,...k the maximizer of entropy is an f0 that is pro- portional to exp(. ∑ ci hi ) for some choice of ci . An extension of this to a continuum of.

  1. All-normal-dispersion fiber laser with NALM: power scalability of the single-pulse regime

    Science.gov (United States)

    Gao, Gan; Zhang, Haitao; Li, Yuhe; Deng, Decai

    2018-03-01

    We investigate the average power scalability of all-normal-dispersion fiber integrated lasers with a nonlinear amplifying loop. This laser generates 34 ps pulses at a repetition of 8 MHz and spectral width of 30 nm when increased to the highest power. The laser operates on a single-pulse train regime and can be de-chirped as short as 200 fs. The 60 mW output power which can be maintained while operating with low Raman effect is the highest average power achieved for this type of laser in the sub-200 fs regime. The laser becomes unstable due to the strengthening of the Raman–Stokes pulse. Output pulses show great stability in testing.

  2. Timing Solution and Single-pulse Properties for Eight Rotating Radio Transients

    Energy Technology Data Exchange (ETDEWEB)

    Cui, B.-Y.; McLaughlin, M. A. [Department of Physics and Astronomy West Virginia University Morgantown, WV 26506 (United States); Boyles, J. [Department of Physics and Astronomy West Kentucky University Bowling Green, KY 42101 (United States); Palliyaguru, N. [Physics and Astronomy Department Texas Tech University Lubbock, TX 79409-1051 (United States)

    2017-05-01

    Rotating radio transients (RRATs), loosely defined as objects that are discovered through only their single pulses, are sporadic pulsars that have a wide range of emission properties. For many of them, we must measure their periods and determine timing solutions relying on the timing of their individual pulses, while some of the less sporadic RRATs can be timed by using folding techniques as we do for other pulsars. Here, based on Parkes and Green Bank Telescope (GBT) observations, we introduce our results on eight RRATs including their timing-derived rotation parameters, positions, and dispersion measures (DMs), along with a comparison of the spin-down properties of RRATs and normal pulsars. Using data for 24 RRATs, we find that their period derivatives are generally larger than those of normal pulsars, independent of any intrinsic correlation with period, indicating that RRATs’ highly sporadic emission may be associated with intrinsically larger magnetic fields. We carry out Lomb–Scargle tests to search for periodicities in RRATs’ pulse detection times with long timescales. Periodicities are detected for all targets, with significant candidates of roughly 3.4 hr for PSR J1623−0841 and 0.7 hr for PSR J1839−0141. We also analyze their single-pulse amplitude distributions, finding that log-normal distributions provide the best fits, as is the case for most pulsars. However, several RRATs exhibit power-law tails, as seen for pulsars emitting giant pulses. This, along with consideration of the selection effects against the detection of weak pulses, imply that RRAT pulses generally represent the tail of a normal intensity distribution.

  3. Timing Solution and Single-pulse Properties for Eight Rotating Radio Transients

    Science.gov (United States)

    Cui, B.-Y.; Boyles, J.; McLaughlin, M. A.; Palliyaguru, N.

    2017-05-01

    Rotating radio transients (RRATs), loosely defined as objects that are discovered through only their single pulses, are sporadic pulsars that have a wide range of emission properties. For many of them, we must measure their periods and determine timing solutions relying on the timing of their individual pulses, while some of the less sporadic RRATs can be timed by using folding techniques as we do for other pulsars. Here, based on Parkes and Green Bank Telescope (GBT) observations, we introduce our results on eight RRATs including their timing-derived rotation parameters, positions, and dispersion measures (DMs), along with a comparison of the spin-down properties of RRATs and normal pulsars. Using data for 24 RRATs, we find that their period derivatives are generally larger than those of normal pulsars, independent of any intrinsic correlation with period, indicating that RRATs’ highly sporadic emission may be associated with intrinsically larger magnetic fields. We carry out Lomb-Scargle tests to search for periodicities in RRATs’ pulse detection times with long timescales. Periodicities are detected for all targets, with significant candidates of roughly 3.4 hr for PSR J1623-0841 and 0.7 hr for PSR J1839-0141. We also analyze their single-pulse amplitude distributions, finding that log-normal distributions provide the best fits, as is the case for most pulsars. However, several RRATs exhibit power-law tails, as seen for pulsars emitting giant pulses. This, along with consideration of the selection effects against the detection of weak pulses, imply that RRAT pulses generally represent the tail of a normal intensity distribution.

  4. Maximizers versus satisficers

    Directory of Open Access Journals (Sweden)

    Andrew M. Parker

    2007-12-01

    Full Text Available Our previous research suggests that people reporting a stronger desire to maximize obtain worse life outcomes (Bruine de Bruin et al., 2007. Here, we examine whether this finding may be explained by the decision-making styles of self-reported maximizers. Expanding on Schwartz et al. (2002, we find that self-reported maximizers are more likely to show problematic decision-making styles, as evidenced by self-reports of less behavioral coping, greater dependence on others when making decisions, more avoidance of decision making, and greater tendency to experience regret. Contrary to predictions, self-reported maximizers were more likely to report spontaneous decision making. However, the relationship between self-reported maximizing and worse life outcomes is largely unaffected by controls for measures of other decision-making styles, decision-making competence, and demographic variables.

  5. Effects of single pulse energy on the properties of ceramic coating prepared by micro-arc oxidation on Ti alloy

    International Nuclear Information System (INIS)

    Wang, Jun-Hua; Wang, Jin; Lu, Yan; Du, Mao-Hua; Han, Fu-Zhu

    2015-01-01

    Highlights: • Single pulse energy remarkably influences the properties of ceramic coating prepared by MAO on Ti alloy. • The accumulative time of impulse width is an important parameter in the scientific and rational measurement of the film forming law of ceramic coating. • The ceramic coating thickness approximately linearly increases with the cumulative time of impulse width. • Larger impulse width resulted in higher single pulse energy, film forming rates and thicker ceramic coating thickness. • The effects of single pulse energy on the micro-hardness and phase composition of ceramic coating are not as evident as those of frequency and duty cycle. - Abstract: The effects of single pulse energy on the properties of ceramic coating fabricated on a Ti–6Al–4V alloy via micro-arc oxidation (MAO) in aqueous solutions containing aluminate, phosphate, and some additives are investigated. The thickness, micro-hardness, surface and cross-sectional morphology, surface roughness, and compositions of the ceramic coating are studied using eddy current thickness meter, micro-hardness tester, JB-4C Precision Surface roughness meter, scanning electron microscopy (SEM) and X-ray diffraction (XRD). Single pulse energy remarkably influences the ceramic coating properties. The accumulative time of impulse width is an important parameter in the scientific and rational measurement of the film forming law of ceramic coating. The ceramic coating thickness approximately linearly increases with the cumulative time of impulse width. Larger impulse width resulted in higher single pulse energy, film forming rates and thicker ceramic coating thickness. The sizes of oxide particles, micro-pores and micro-cracks slightly increase with impulse width and single pulse energy. The main surface conversion products generated during MAO process in aqueous solutions containing aluminate are rutile TiO 2 , anatase TiO 2 , and a large amount of Al 2 TiO 5 . The effects of single pulse

  6. Effects of single pulse energy on the properties of ceramic coating prepared by micro-arc oxidation on Ti alloy

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Jun-Hua [Department of Mechanical Engineering, Tsinghua University, Beijing 100084 (China); School of Materials Science and Engineering, Henan University of Science and Technology, Luoyang 471023 (China); Faculty of Mechanical and Electrical Engineering, Kunming University of Science and Technology, Kunming 650500 (China); Wang, Jin [Department of Mechanical Engineering, Tsinghua University, Beijing 100084 (China); Beijing Key Lab of Precision/Ultra-precision Manufacturing Equipments and Control, Beijing 100084 (China); Lu, Yan [School of Materials Science and Engineering, Henan University of Science and Technology, Luoyang 471023 (China); Du, Mao-Hua [Faculty of Mechanical and Electrical Engineering, Kunming University of Science and Technology, Kunming 650500 (China); Han, Fu-Zhu, E-mail: hanfuzhu@mail.tsinghua.edu.cn [Department of Mechanical Engineering, Tsinghua University, Beijing 100084 (China); Beijing Key Lab of Precision/Ultra-precision Manufacturing Equipments and Control, Beijing 100084 (China)

    2015-01-01

    Highlights: • Single pulse energy remarkably influences the properties of ceramic coating prepared by MAO on Ti alloy. • The accumulative time of impulse width is an important parameter in the scientific and rational measurement of the film forming law of ceramic coating. • The ceramic coating thickness approximately linearly increases with the cumulative time of impulse width. • Larger impulse width resulted in higher single pulse energy, film forming rates and thicker ceramic coating thickness. • The effects of single pulse energy on the micro-hardness and phase composition of ceramic coating are not as evident as those of frequency and duty cycle. - Abstract: The effects of single pulse energy on the properties of ceramic coating fabricated on a Ti–6Al–4V alloy via micro-arc oxidation (MAO) in aqueous solutions containing aluminate, phosphate, and some additives are investigated. The thickness, micro-hardness, surface and cross-sectional morphology, surface roughness, and compositions of the ceramic coating are studied using eddy current thickness meter, micro-hardness tester, JB-4C Precision Surface roughness meter, scanning electron microscopy (SEM) and X-ray diffraction (XRD). Single pulse energy remarkably influences the ceramic coating properties. The accumulative time of impulse width is an important parameter in the scientific and rational measurement of the film forming law of ceramic coating. The ceramic coating thickness approximately linearly increases with the cumulative time of impulse width. Larger impulse width resulted in higher single pulse energy, film forming rates and thicker ceramic coating thickness. The sizes of oxide particles, micro-pores and micro-cracks slightly increase with impulse width and single pulse energy. The main surface conversion products generated during MAO process in aqueous solutions containing aluminate are rutile TiO{sub 2}, anatase TiO{sub 2}, and a large amount of Al{sub 2}TiO{sub 5}. The effects of

  7. Interaction of single-pulse laser energy with bow shock in hypersonic flow

    Directory of Open Access Journals (Sweden)

    Hong Yanji

    2014-04-01

    Full Text Available Pressure sensing and schlieren imaging with high resolution and sensitivity are applied to the study of the interaction of single-pulse laser energy with bow shock at Mach 5. An Nd:YAG laser operated at 1.06 μm, 100 mJ pulse energy is used to break down the hypersonic flow in a shock tunnel. Three-dimensional Navier–Stokes equations are solved with an upwind scheme to simulate the interaction. The pressure at the stagnation point on the blunt body is measured and calculated to examine the pressure variation during the interaction. Schlieren imaging is used in conjunction with the calculated density gradients to examine the process of the interaction. The results show that the experimental pressure at the stagnation point on the blunt body and schlieren imaging fit well with the simulation. The pressure at the stagnation point on the blunt body will increase when the transmission shock approaches the blunt body and decrease with the formation of the rarefied wave. Bow shock is deformed during the interaction. Quasi-stationary waves are formed by high rate laser energy deposition to control the bow shock. The pressure and temperature at the stagnation point on the blunt body and the wave drag are reduced to 50%, 75% and 81% respectively according to the simulation. Schlieren imaging has provided important information for the investigation of the mechanism of the interaction.

  8. Surface microstructure and chemistry of polyimide by single pulse ablation of picosecond laser

    Science.gov (United States)

    Du, Qifeng; Chen, Ting; Liu, Jianguo; Zeng, Xiaoyan

    2018-03-01

    Polyimide (PI) surface was ablated by the single pulse of picosecond laser, and the effects of laser wavelength (λ= 355 nm and 1064 nm) and fluence on surface microstructure and chemistry were explored. Scanning electron microscopy (SEM) analysis found that different surface microstructures, i.e., the concave of concentric ring and the convex of porous circular disk, were generated by 355 nm and 1064 nm picosecond laser ablation, respectively. X-ray photoelectron spectroscopy (XPS) characterization indicated that due to the high peak energy density of picosecond laser, oxygen and nitrogen from the ambient were incorporated into the PI surface mainly in the form of Cdbnd O and Csbnd Nsbnd C groups. Thus, both of the O/C and N/C atomic content ratios increased, but the increase caused by 1064 nm wavelength laser was larger. It inferred that the differences of PI surface microstructures and chemistry resulted from different laser parameters were related to different laser-matter interaction effects. For 355 nm picosecond laser, no obvious thermal features were observed and the probable ablation process of PI was mainly governed by photochemical effect; while for 1064 nm picosecond laser, obvious thermal feature appeared and photothermal effect was thought to be dominant.

  9. Single-pulse x-ray diffraction using polycapillary optics for in situ dynamic diffraction

    Energy Technology Data Exchange (ETDEWEB)

    Maddox, B. R., E-mail: maddox3@llnl.gov; Akin, M. C., E-mail: akin1@llnl.gov; Teruya, A.; Hunt, D.; Hahn, D.; Cradick, J. [Lawrence Livermore National Laboratory, Livermore, California 94550 (United States); Morgan, D. V. [National Security Technologies LLC, Los Alamos, New Mexico 87544 (United States)

    2016-08-15

    Diagnostic use of single-pulse x-ray diffraction (XRD) at pulsed power facilities can be challenging due to factors such as the high flux and brightness requirements for diffraction and the geometric constraints of experimental platforms. By necessity, the x-ray source is usually positioned very close, within a few inches of the sample. On dynamic compression platforms, this puts the x-ray source in the debris field. We coupled x-ray polycapillary optics to a single-shot needle-and-washer x-ray diode source using a laser-based alignment scheme to obtain high-quality x-ray diffraction using a single 16 ns x-ray pulse with the source >1 m from the sample. The system was tested on a Mo sample in reflection geometry using 17 keV x-rays from a Mo anode. We also identified an anode conditioning effect that increased the x-ray intensity by 180%. Quantitative measurements of the x-ray focal spot produced by the polycapillary yielded a total x-ray flux on the sample of 3.3 ± 0.5 × 10{sup 7} molybdenum Kα photons.

  10. Single-pulse CARS based multimodal nonlinear optical microscope for bioimaging.

    Science.gov (United States)

    Kumar, Sunil; Kamali, Tschackad; Levitte, Jonathan M; Katz, Ori; Hermann, Boris; Werkmeister, Rene; Považay, Boris; Drexler, Wolfgang; Unterhuber, Angelika; Silberberg, Yaron

    2015-05-18

    Noninvasive label-free imaging of biological systems raises demand not only for high-speed three-dimensional prescreening of morphology over a wide-field of view but also it seeks to extract the microscopic functional and molecular details within. Capitalizing on the unique advantages brought out by different nonlinear optical effects, a multimodal nonlinear optical microscope can be a powerful tool for bioimaging. Bringing together the intensity-dependent contrast mechanisms via second harmonic generation, third harmonic generation and four-wave mixing for structural-sensitive imaging, and single-beam/single-pulse coherent anti-Stokes Raman scattering technique for chemical sensitive imaging in the finger-print region, we have developed a simple and nearly alignment-free multimodal nonlinear optical microscope that is based on a single wide-band Ti:Sapphire femtosecond pulse laser source. Successful imaging tests have been realized on two exemplary biological samples, a canine femur bone and collagen fibrils harvested from a rat tail. Since the ultra-broad band-width femtosecond laser is a suitable source for performing high-resolution optical coherence tomography, a wide-field optical coherence tomography arm can be easily incorporated into the presented multimodal microscope making it a versatile optical imaging tool for noninvasive label-free bioimaging.

  11. Single Pulse Electrical Stimulation to identify epileptogenic cortex: Clinical information obtained from early evoked responses.

    Science.gov (United States)

    Mouthaan, B E; van 't Klooster, M A; Keizer, D; Hebbink, G J; Leijten, F S S; Ferrier, C H; van Putten, M J A M; Zijlmans, M; Huiskamp, G J M

    2016-02-01

    Single Pulse Electrical Stimulation (SPES) probes epileptogenic cortex during electrocorticography. Two SPES responses are described: pathological delayed responses (DR, >100 ms) associated with the seizure onset zone (SOZ) and physiological early responses (ER, 80 Hz, in the SOZ and seizure propagation areas. We used data from 12 refractory epilepsy patients. SPES consisted of 10 pulses of 1 ms, 4-8 mA and 5s interval on adjacent electrodes pairs. Data were available at 2048 samples/s for six and 512 samples/s (22 bits) for eight patients and analyzed in the time-frequency (TF) and time-domain (TD). Electrodes with ERs were stronger associated with SOZ than non-SOZ electrodes. ERs with frequency content >80 Hz exist and are specific for SOZ channels. ERs evoked by stimulation of seizure onset electrodes were associated with electrodes involved in seizure propagation. Analysis of ERs can reveal aspects of pathology, manifested by association with seizure propagation and areas with high ER numbers that coincide with the SOZ. Not only DRs, but also ERs could have clinical value for mapping epileptogenic cortex and help to unravel aspects of the epileptic network. Copyright © 2015 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  12. Investigating emotional top down modulation of ambiguous faces by single pulse TMS on early visual cortices

    Directory of Open Access Journals (Sweden)

    Zachary Adam Yaple

    2016-06-01

    Full Text Available Top-down processing is a mechanism in which memory, context and expectation are used to perceive stimuli. For this study we investigated how emotion content, induced by music mood, influences perception of happy and sad emoticons. Using single pulse TMS we stimulated right occipital face area (rOFA, primary visual cortex (V1 and vertex while subjects performed a face-detection task and listened to happy and sad music. At baseline, incongruent audio-visual pairings decreased performance, demonstrating dependence of emotion while perceiving ambiguous faces. However, performance of face identification decreased during rOFA stimulation regardless of emotional content. No effects were found between Cz and V1 stimulation. These results suggest that while rOFA is important for processing faces regardless of emotion, V1 stimulation had no effect. Our findings suggest that early visual cortex activity may not integrate emotional auditory information with visual information during emotion top-down modulation of faces.

  13. Surprise in simplicity: an unusual spectral evolution of a single pulse GRB 151006A

    Science.gov (United States)

    Basak, R.; Iyyani, S.; Chand, V.; Chattopadhyay, T.; Bhattacharya, D.; Rao, A. R.; Vadawale, S. V.

    2017-11-01

    We present a detailed analysis of GRB 151006A, the first gamma-ray burst (GRB) detected by AstroSat Cadmium-Zinc-Telluride Imager (CZTI). We study the long-term spectral evolution by exploiting the capabilities of Fermi and Swift satellites at different phases, which is complemented by the polarization measurement with the CZTI. While the light curve of the GRB in different energy bands shows a simple pulse profile, the spectrum shows an unusual evolution. The first phase exhibits a hard-to-soft evolution until ∼16-20 s, followed by a sudden increase in the spectral peak reaching a few MeV. Such a dramatic change in the spectral evolution in the case of a single pulse burst is reported for the first time. This is captured by all models we used namely, Band function, blackbody+Band and two blackbodies+power law. Interestingly, the Fermi Large Area Telescope also detects its first photon (>100 MeV) during this time. This new injection of energy may be associated with either the beginning of afterglow phase, or a second hard pulse of the prompt emission itself that, however, is not seen in the otherwise smooth pulse profile. By constructing Bayesian blocks and studying the hardness evolution we find a good evidence for a second hard pulse. The Swift data at late epochs (>T90 of the GRB) also show a significant spectral evolution consistent with the early second phase. The CZTI data (100-350 keV), though having low significance (1σ), show high values of polarization in the two epochs (77-94 per cent), in agreement with our interpretation.

  14. Object-oriented identification of forested landslides with derivatives of single pulse LiDAR data

    Science.gov (United States)

    Van Den Eeckhaut, Miet; Kerle, Norman; Poesen, Jean; Hervás, Javier

    2012-11-01

    In contrast to the many studies that use expert-based analysis of LiDAR derivatives for landslide mapping in forested terrain, only few studies have attempted to develop (semi-)automatic methods for extracting landslides from LiDAR derivatives. While all these studies are pixel-based, it has not yet been tested whether object-oriented analysis (OOA) could be an alternative. This study investigates the potential of OOA using only single-pulse LiDAR derivatives, such as slope gradient, roughness and curvature to map landslides. More specifically, the focus is on both LiDAR data segmentation and classification of slow-moving landslides in densely vegetated areas, where spectral data do not allow accurate landslide identification. A multistage procedure has been developed and tested in the Flemish Ardennes (Belgium). The procedure consists of (1) image binarization and multiresolution segmentation, (2) classification of landslide parts (main scarps and landslide body segments) and non-landslide features (i.e. earth banks and cropland fields) with supervised support vector machines at the appropriate scale, (3) delineation of landslide flanks, (4) growing of a landslide body starting from its main scarp, and (5) final cleaning of the inventory map. The results obtained show that OOA using LiDAR derivatives allows recognition and characterization of profound morphologic properties of forested deep-seated landslides on soil-covered hillslopes, because more than 90% of the main scarps and 70% of the landslide bodies of an expert-based inventory were accurately identified with OOA. For mountainous areas with bedrock, on the other hand, creation of a transferable model is expected to be more difficult.

  15. Meterwavelength Single-pulse Polarimetric Emission Survey. IV. The Period Dependence of Component Widths of Pulsars

    Science.gov (United States)

    Skrzypczak, Anna; Basu, Rahul; Mitra, Dipanjan; Melikidze, George I.; Maciesiak, Krzysztof; Koralewska, Olga; Filothodoros, Alexandros

    2018-02-01

    The core component width in normal pulsars, with periods (P) > 0.1 s, measured at the half-power point at 1 GHz, has a lower boundary line (LBL) that closely follows the P ‑0.5 scaling relation. This result is of fundamental importance for understanding the emission process and requires extended studies over a wider frequency range. In this paper we have carried out a detailed study of the profile component widths of 123 normal pulsars observed in the Meterwavelength Single-pulse Polarimetric Emission Survey at 333 and 618 MHz. The components in the pulse profile were separated into core and conal classes. We found that at both frequencies, the core, as well as the conal component widths versus period, had a LBL that followed the P ‑0.5 relation with a similar lower boundary. The radio emission in normal pulsars has been observationally shown to arise from a narrow range of heights around a few hundred kilometers above the stellar surface. In the past the P ‑0.5 relation has been considered as evidence for emission arising from last open dipolar magnetic field lines. We show that the P ‑0.5 dependence only holds if the trailing and leading half-power points of the component are associated with the last open field line. In such a scenario we do not find any physical motivation that can explain the P ‑0.5 dependence for both core and conal components as evidence for dipolar geometry in normal pulsars. We believe the period dependence is a result of a currently unexplained physical phenomenon.

  16. Single pulse vibrational Raman scattering by a broadband KrF excimer laser in a hydrogen-air flame

    Science.gov (United States)

    Pitz, Robert W.; Wehrmeyer, Joseph A.; Bowling, J. M.; Cheng, Tsarng-Sheng

    1990-01-01

    Spontaneous vibrational Raman scattering (VRS) is produced by a broadband excimer laser at 248 nm (KrF) in a H2-air flame, and VRS spectra are recorded for lean, stoichiometric, and rich flames. Except at very lean flame conditions, laser-induced fluorescence (LIF) processes interfere with VRS Stokes lines from H2, H2O, and O2. No interference is found for the N2 Stokes and N2 anti-Stokes lines. In a stoichiometric H2/air flame, single-pulse measurements of N2 concentration and temperature (by the VRS Stokes to anti-Stokes ratio) have a relative standard deviation of 7.7 and 10 percent, respectively. These single pulse measurement errors compare well with photon statistics calculations using measured Raman cross sections.

  17. A Novel Single Pulsed Electromagnetic Field Stimulates Osteogenesis of Bone Marrow Mesenchymal Stem Cells and Bone Repair

    OpenAIRE

    Fu, Yin-Chih; Lin, Chih-Chun; Chang, Je-Ken; Chen, Chung-Hwan; Tai, I-Chun; Wang, Gwo-Jaw; Ho, Mei-Ling

    2014-01-01

    Pulsed electromagnetic field (PEMF) has been successfully applied to accelerate fracture repair since 1979. Recent studies suggest that PEMF might be used as a nonoperative treatment for the early stages of osteonecrosis. However, PEMF treatment requires a minimum of ten hours per day for the duration of the treatment. In this study, we modified the protocol of the single-pulsed electromagnetic field (SPEMF) that only requires a 3-minute daily treatment. In the in vitro study, cell proliferat...

  18. Resource allocation for maximizing prediction accuracy and genetic gain of genomic selection in plant breeding: a simulation experiment.

    Science.gov (United States)

    Lorenz, Aaron J

    2013-03-01

    Allocating resources between population size and replication affects both genetic gain through phenotypic selection and quantitative trait loci detection power and effect estimation accuracy for marker-assisted selection (MAS). It is well known that because alleles are replicated across individuals in quantitative trait loci mapping and MAS, more resources should be allocated to increasing population size compared with phenotypic selection. Genomic selection is a form of MAS using all marker information simultaneously to predict individual genetic values for complex traits and has widely been found superior to MAS. No studies have explicitly investigated how resource allocation decisions affect success of genomic selection. My objective was to study the effect of resource allocation on response to MAS and genomic selection in a single biparental population of doubled haploid lines by using computer simulation. Simulation results were compared with previously derived formulas for the calculation of prediction accuracy under different levels of heritability and population size. Response of prediction accuracy to resource allocation strategies differed between genomic selection models (ridge regression best linear unbiased prediction [RR-BLUP], BayesCπ) and multiple linear regression using ordinary least-squares estimation (OLS), leading to different optimal resource allocation choices between OLS and RR-BLUP. For OLS, it was always advantageous to maximize population size at the expense of replication, but a high degree of flexibility was observed for RR-BLUP. Prediction accuracy of doubled haploid lines included in the training set was much greater than of those excluded from the training set, so there was little benefit to phenotyping only a subset of the lines genotyped. Finally, observed prediction accuracies in the simulation compared well to calculated prediction accuracies, indicating these theoretical formulas are useful for making resource allocation

  19. Novel Approach for Maximizing Follow-Up in Cosmetic Surgery Clinical Trials: The Ideal Implant Core Trial Experience.

    Science.gov (United States)

    Mueller, Melissa A; Nichter, Larry S; Hamas, Robert S

    2017-10-01

    High follow-up rates are critical for robust research with minimal bias, and are particularly important for breast implant Core Studies seeking U.S. Food and Drug Administration approval. The Core Study for IDEAL IMPLANT, the most recently U.S. Food and Drug Administration-approved breast implant, used a novel incentive payment model to achieve higher follow-up rates than in previous breast implant trials. At enrollment, $3500 was deposited into an independent, irrevocable trust for each of the 502 subjects and invested in a diversified portfolio. If a follow-up visit is missed, the subject is exited from the study and compensated for completed visits, but the remainder of her share of the funds stay in the trust. At the conclusion of the 10-year study, the trust will be divided among those subjects who completed all required follow-up visits. For primary and revision augmentation cohorts, the U.S. Food and Drug Administration published follow-up rates from Core Studies were compared for all currently available breast implants. Five-year follow-up rates for the IDEAL IMPLANT Core Study are higher for both primary augmentation and revision augmentation cohorts (94.9 percent and 96.7 percent, respectively) when compared to all other trials that have used U.S. Food and Drug Administration standardized follow-up reporting (MemoryShape, Allergan 410, and Sientra Core Studies). This trial demonstrates the utility of a novel incentive strategy to maximize follow-up in cosmetic surgery patients. This strategy may benefit future cosmetic surgery trials and perhaps any prospective research trial by providing more complete data. Therapeutic, IV.

  20. Genelab: Scientific Partnerships and an Open-Access Database to Maximize Usage of Omics Data from Space Biology Experiments

    Science.gov (United States)

    Reinsch, S. S.; Galazka, J..; Berrios, D. C; Chakravarty, K.; Fogle, H.; Lai, S.; Bokyo, V.; Timucin, L. R.; Tran, P.; Skidmore, M.

    2016-01-01

    NASA's mission includes expanding our understanding of biological systems to improve life on Earth and to enable long-duration human exploration of space. The GeneLab Data System (GLDS) is NASA's premier open-access omics data platform for biological experiments. GLDS houses standards-compliant, high-throughput sequencing and other omics data from spaceflight-relevant experiments. The GeneLab project at NASA-Ames Research Center is developing the database, and also partnering with spaceflight projects through sharing or augmentation of experiment samples to expand omics analyses on precious spaceflight samples. The partnerships ensure that the maximum amount of data is garnered from spaceflight experiments and made publically available as rapidly as possible via the GLDS. GLDS Version 1.0, went online in April 2015. Software updates and new data releases occur at least quarterly. As of October 2016, the GLDS contains 80 datasets and has search and download capabilities. Version 2.0 is slated for release in September of 2017 and will have expanded, integrated search capabilities leveraging other public omics databases (NCBI GEO, PRIDE, MG-RAST). Future versions in this multi-phase project will provide a collaborative platform for omics data analysis. Data from experiments that explore the biological effects of the spaceflight environment on a wide variety of model organisms are housed in the GLDS including data from rodents, invertebrates, plants and microbes. Human datasets are currently limited to those with anonymized data (e.g., from cultured cell lines). GeneLab ensures prompt release and open access to high-throughput genomics, transcriptomics, proteomics, and metabolomics data from spaceflight and ground-based simulations of microgravity, radiation or other space environment factors. The data are meticulously curated to assure that accurate experimental and sample processing metadata are included with each data set. GLDS download volumes indicate strong

  1. Impact of pulse duration on Ho:YAG laser lithotripsy: treatment aspects on the single-pulse level.

    Science.gov (United States)

    Sroka, Ronald; Pongratz, Thomas; Scheib, Gabriel; Khoder, Wael; Stief, Christian G; Herrmann, Thomas; Nagele, Udo; Bader, Markus J

    2015-04-01

    Holmium-YAG (Ho:YAG) laser lithotripsy is a multi-pulse treatment modality with stochastic effects on the fragmentation. In vitro investigation on the single-pulse-induced effects on fiber, repulsion as well as fragmentation was performed to identify potential impacts of different Ho:YAG laser pulse durations. A Ho:YAG laser system (Swiss LaserClast, EMS S.A., Nyon, Switzerland) with selectable long- or short-pulse mode was tested with regard to fiber burn back, the repulsion capacity using an underwater pendulum setup and single-pulse-induced fragmentation capacity using artificial (BEGO) stones. The laser parameters were chosen in accordance with clinical application modes (laser fiber: 365 and 200 µm; output power: 4, 6 and 10 W in different combinations of energy per pulse and repetition rate). Evaluation parameters were reduction in fiber length, pendulum deviation and topology of the crater. Using the long-pulse mode, the fiber burn back was nearly negligible, while in short-pulse mode, an increased burn back could be observed. The results of the pendulum test showed that the deviation induced by the momentum of short pulses was by factor 1.5-2 higher compared to longer pulses at identical energy per pulse settings. The ablation volumes induced by single pulses either in short-pulse or long-pulse mode did not differ significantly although different crater shapes appeared. Reduced stone repulsion and reduced laser fiber burn back with longer laser pulses may result in a more convenient handling during clinical application and thus in an improved clinical outcome of laser lithotripsy.

  2. Single-pulse characteristics of the Xe(L) amplifier on the Xe35+ (3d→2p) transition array at λ ≅ 2.86 A

    International Nuclear Information System (INIS)

    Borisov, Alex B; Song Xiangyang; Zhang Ping; McCorkindale, John C; Khan, Shahab F; De Jonghe, Richard; Poopalasingam, Sankar; Zhao, Ji; Boyer, Keith; Rhodes, Charles K

    2006-01-01

    The triple comparison of (1) single-pulse spectral data, recorded with a CCD-equipped von Hamos spectrometer both axially and transversely; (2) axially measured time-integrated spectra registered on a film and (3) single-pulse x-ray images of the morphology of the self-trapped plasma channel, recorded simultaneously with the single-pulse spectra, establishes several leading characteristics of the saturated amplification observed on the Xe 35+ transition array at λ ≅ 2.86 A. The chief findings are (α) absolute positive correlation of amplification with the formation of a plasma channel, (β) a perfect spectral match of the amplified transitions in the comparison of axially recorded single-pulse and time-integrated film data and (γ) exact spectral correspondence of both the axially registered single-pulse and time-integrated film data with single-pulse transversely measured spectra exhibiting deep spectral hole burning at the position of the Xe 35+ array. (letter to the editor)

  3. Dance-Based ExerGaming: User Experience Design Implications for Maximizing Health Benefits Based on Exercise Intensity and Perceived Enjoyment

    Science.gov (United States)

    Thin, Alasdair G.; Poole, Nicola

    Dance is a form of exercise that is considered to have widespread popular appeal and in particular to adolescent females. Dance-based body-movement controlled video games are a popular form of ExerGaming that is being adopted for use in school-based physical activity health promotion programs. The results of this study indicate that the game play mechanics and skill demands of the dance-based ExerGames would appear to have limited the subjects' level of physical exertion over the period of study. After training there was an increase in enjoyment rating for the Step Aerobics game which appears related to a perceptible improvement in game performance. It is therefore recommended that ExerGames should be designed with very low initial skill demands in order to maximize the user's level of exertion and to realize and reward progress, thereby helping to promote an enjoyable exercise experience and counterbalance any sense of exertional discomfort. Keywords: exercise; health promotion; exergaming; user experience; design; video game; enjoyment.

  4. The Israeli EA-FEL Upgrade Towards Long Pulse Operation for Ultra-High Resolution Single Pulse Coherent Spectroscopy

    CERN Document Server

    Gover, A; Kanter, M; Kapilevich, B; Litvak, B; Peleg, S; Socol, Y; Volshonok, M

    2005-01-01

    The Israeli Electrostatic Accelerator FEL (EA-FEL) is now being upgraded towards long pulse (1005s) operation and ultra-high resolution (10(-6)) single pulse coherent spectroscopy. We present quantitative estimations regarding the applications of controlled radiation chirp for spectroscopic applications with pulse-time Fourier Transform limited spectral resolution. Additionally, we describe a novel extraction-efficiency-improving scheme based on increase of accelerating voltage (boosting) after saturation is achieved. The efficiency of the proposed scheme is confirmed by theoretical and numerical calculations. The latter are performed using software, based on 3D space-frequency domain model. The presentation provides an overview of the upgrade status: the high-voltage terminal is being reconfigured to accept the accelerating voltage boost system; a new broad band low-loss resonator is being manufactured; multi-stage depressed collector is assembled.

  5. Maximizing and customer loyalty: Are maximizers less loyal?

    Directory of Open Access Journals (Sweden)

    Linda Lai

    2011-06-01

    Full Text Available Despite their efforts to choose the best of all available solutions, maximizers seem to be more inclined than satisficers to regret their choices and to experience post-decisional dissonance. Maximizers may therefore be expected to change their decisions more frequently and hence exhibit lower customer loyalty to providers of products and services compared to satisficers. Findings from the study reported here (N = 1978 support this prediction. Maximizers reported significantly higher intentions to switch to another service provider (television provider than satisficers. Maximizers' intentions to switch appear to be intensified and mediated by higher proneness to regret, increased desire to discuss relevant choices with others, higher levels of perceived knowledge of alternatives, and higher ego involvement in the end product, compared to satisficers. Opportunities for future research are suggested.

  6. Maximally incompatible quantum observables

    Energy Technology Data Exchange (ETDEWEB)

    Heinosaari, Teiko, E-mail: teiko.heinosaari@utu.fi [Turku Centre for Quantum Physics, Department of Physics and Astronomy, University of Turku, FI-20014 Turku (Finland); Schultz, Jussi, E-mail: jussi.schultz@gmail.com [Dipartimento di Matematica, Politecnico di Milano, Piazza Leonardo da Vinci 32, I-20133 Milano (Italy); Toigo, Alessandro, E-mail: alessandro.toigo@polimi.it [Dipartimento di Matematica, Politecnico di Milano, Piazza Leonardo da Vinci 32, I-20133 Milano (Italy); Istituto Nazionale di Fisica Nucleare, Sezione di Milano, Via Celoria 16, I-20133 Milano (Italy); Ziman, Mario, E-mail: ziman@savba.sk [RCQI, Institute of Physics, Slovak Academy of Sciences, Dúbravská cesta 9, 84511 Bratislava (Slovakia); Faculty of Informatics, Masaryk University, Botanická 68a, 60200 Brno (Czech Republic)

    2014-05-01

    The existence of maximally incompatible quantum observables in the sense of a minimal joint measurability region is investigated. Employing the universal quantum cloning device it is argued that only infinite dimensional quantum systems can accommodate maximal incompatibility. It is then shown that two of the most common pairs of complementary observables (position and momentum; number and phase) are maximally incompatible.

  7. Profit maximization mitigates competition

    DEFF Research Database (Denmark)

    Dierker, Egbert; Grodal, Birgit

    1996-01-01

    We consider oligopolistic markets in which the notion of shareholders' utility is well-defined and compare the Bertrand-Nash equilibria in case of utility maximization with those under the usual profit maximization hypothesis. Our main result states that profit maximization leads to less price...

  8. Shifts in the metabolic function of a benthic estuarine microbial community following a single pulse exposure to silver nanoparticles

    International Nuclear Information System (INIS)

    Echavarri-Bravo, Virginia; Paterson, Lynn; Aspray, Thomas J.; Porter, Joanne S.; Winson, Michael K.; Thornton, Barry; Hartl, Mark G.J.

    2015-01-01

    The increasing use of silver nanoparticles (AgNPs) as a biocidal agent and their potential accumulation in sediments may threaten non-target natural environmental bacterial communities. In this study a microcosm approach was established to investigate the effects of well characterized OECD AgNPs (NM-300) on the function of the bacterial community inhabiting marine estuarine sediments (salinity 31‰). The results showed that a single pulse of NM-300 AgNPs (1 mg L −1 ) that led to sediment concentrations below 6 mg Ag kg −1 dry weight inhibited the bacterial utilization of environmentally relevant carbon substrates. As a result, the functional diversity changed, but recovered after 120 h under the experimental conditions. This microcosm study suggests that AgNPs under environmentally relevant experimental conditions can negatively affect bacterial function and provides an insight into the understanding of the bacterial community response and resilience to AgNPs exposure, important for informing relevant regulatory measures. - Highlights: • AgNPs affected the bacterial community function in estuarine marine sediments. • AgNPs inhibited the bacterial utilization of environmentally relevant substrates. • Heterotrophic bacterial groups showed resilience to AgNPs after 120 h exposure. • AgNPs did not affect the bacterial community structure in sediments. - AgNPs inhibited the bacterial utilization of environmentally relevant substrates and caused temporary shifts in the bacterial functional diversity in marine estuarine sediments

  9. Single-pulse observations of the Galactic Center magnetar PSR J1745-2900 at 3.1 GHz

    Science.gov (United States)

    Yan, W. M.; Wang, N.; Manchester, R. N.; Wen, Z. G.; Yuan, J. P.

    2018-02-01

    We report on single-pulse observations of the Galactic Center magnetar PSR J1745-2900 that were made using the Parkes 64-m radio telescope with a central frequency of 3.1 GHz at five observing epochs between 2013 July and August. The shape of the integrated pulse profiles was relatively stable across the five observations, indicating that the pulsar was in a stable state between MJDs 56475 and 56514. This extends the known stable state of this pulsar to 6.8 months. Short term pulse shape variations were also detected. It is shown that this pulsar switches between two emission modes frequently and that the typical duration of each mode is about ten minutes. No giant pulses or subpulse drifting were observed. Apparent nulls in the pulse emission were detected on MJD 56500. Although there are many differences between the radio emission of magnetars and normal radio pulsars, they also share some properties. The detection of mode changing and pulse nulling in PSR J1745-2900 suggests that the basic radio emission process for magnetars and normal pulsars is the same.

  10. Dose rate effect on micronuclei induction in human blood lymphocytes exposed to single pulse and multiple pulses of electrons.

    Science.gov (United States)

    Acharya, Santhosh; Bhat, N N; Joseph, Praveen; Sanjeev, Ganesh; Sreedevi, B; Narayana, Y

    2011-05-01

    The effects of single pulses and multiple pulses of 7 MV electrons on micronuclei (MN) induction in cytokinesis-blocked human peripheral blood lymphocytes (PBLs) were investigated over a wide range of dose rates per pulse (instantaneous dose rate). PBLs were exposed to graded doses of 2, 3, 4, 6, and 8 Gy of single electron pulses of varying pulse widths at different dose rates per pulse, ranging from 1 × 10(6) Gy s(-1) to 3.2 × 10(8) Gy s(-1). Different dose rates per pulse were achieved by changing the dose per electron pulse by adjusting the beam current and pulse width. MN yields per unit absorbed dose after irradiation with single electron pulses were compared with those of multiple pulses of electrons. A significant decrease in the MN yield with increasing dose rates per pulse was observed, when dose was delivered by a single electron pulse. However, no reduction in the MN yield was observed when dose was delivered by multiple pulses of electrons. The decrease in the yield at high dose rates per pulse suggests possible radical recombination, which leads to decreased biological damage. Cellular response to the presence of very large numbers of chromosomal breaks may also alter the damage.

  11. Saturated multikilovolt x-ray amplification with Xe clusters: single-pulse observation of Xe(L) spectral hole burning

    International Nuclear Information System (INIS)

    Borisov, Alex B; Davis, Jack; Song, Xiangyang; Koshman, Yevgeniya; Dai Yang; Boyer, Keith; Rhodes, Charles K

    2003-01-01

    Single-pulse measurements of spectral hole burning of Xe(L) 3d → 2p hollow atom transition arrays observed from a self-trapped plasma channel provide new information on the dynamics of saturated amplification in the λ ∼ 2.8-2.9 A region. The spectral hole burning on transitions in the Xe 34+ and Xe 35+ arrays reaches full suppression of the spontaneous emission and presents a corresponding width Δ h-bar ω x ∼ = 60 eV, a value adequate for efficient amplification of multikilovolt x-ray pulses down to a limiting length τ x ∼ 30 as. The depth of the suppression at 2.86 A indicates that the gain-to-loss ratio is ≥10. An independent determination of the x-ray pulse energy from damage produced on the surface of a Ti foil in the far field of the source gives a pulse energy of 20-30 μJ, a range that correlates well with the observation of the spectral hole burning and indicates an overall extraction efficiency of ∼10%. (letter to the editor)

  12. Residue specific hydration of primary cell wall potato pectin identified by solid-state 13C single-pulse MAS and CP/MAS NMR spectroscopy

    DEFF Research Database (Denmark)

    Larsen, Flemming Hofmann; Chrestensen, Inge Byg; Damager, Iben

    2011-01-01

    Hydration of rhamnogalacturonan-I (RG-I) derived from potato cell wall was analyzed by 13C single-pulse (SP) magic-angle-spinning (MAS) and 13C cross-polarization (CP) MAS nuclear magnetic resonance (NMR) and supported by 2H SP/MAS NMR experiments. The study shows that the arabinan side chains...... hydrate more readily than the galactan side chains and suggests that the overall hydration properties can be controlled by modifying the ratio of these side chains. Enzymatic modification of native (NA) RG-I provided samples with reduced content of arabinan (sample DA), galactan (sample DG), or both side...... chains (sample DB). Results of these samples suggested that hydration properties were determined by the length and character of the side chains. NA and DA exhibited similar hydration characteristics, whereas DG and DB were difficult to hydrate because of the less hydrophilic properties of the rhamnose...

  13. The maximal acceleration group

    International Nuclear Information System (INIS)

    Brandt, H.E.

    1984-01-01

    On the basis of the maximal proper acceleration relative to the vacuum, a line element and differential geometry of eight-dimensional phase space are constructed. The maximal acceleration group is defined as the mathematical transformation group under which the eight dimensional line element is invariant. In the classical limit of vanishing Planck's constant, the maximal acceleration group and geometry reduce to those of general relativity

  14. A novel single pulsed electromagnetic field stimulates osteogenesis of bone marrow mesenchymal stem cells and bone repair.

    Science.gov (United States)

    Fu, Yin-Chih; Lin, Chih-Chun; Chang, Je-Ken; Chen, Chung-Hwan; Tai, I-Chun; Wang, Gwo-Jaw; Ho, Mei-Ling

    2014-01-01

    Pulsed electromagnetic field (PEMF) has been successfully applied to accelerate fracture repair since 1979. Recent studies suggest that PEMF might be used as a nonoperative treatment for the early stages of osteonecrosis. However, PEMF treatment requires a minimum of ten hours per day for the duration of the treatment. In this study, we modified the protocol of the single-pulsed electromagnetic field (SPEMF) that only requires a 3-minute daily treatment. In the in vitro study, cell proliferation and osteogenic differentiation was evaluated in the hBMSCs. In the in vivo study, new bone formation and revascularization were evaluated in the necrotic bone graft. Results from the in vitro study showed no significant cytotoxic effects on the hBMSCs after 5 days of SPEMF treatment (1 Tesla, 30 pulses per day). hBMSC proliferation was enhanced in the SPEMF-treated groups after 2 and 4 days of treatment. The osteogenic differentiation of hBMSCs was significantly increased in the SPEMF-treated groups after 3-7 days of treatment. Mineralization also increased after 10, 15, 20, and 25 days of treatment in SPEMF-treated groups compared to the control group. The 7-day short-course treatment achieved similar effects on proliferation and osteogenesis as the 25-day treatment. Results from the in vivo study also demonstrated that both the 7-day and 25-day treatments of SPEMF increased callus formation around the necrotic bone and also increased new vessel formation and osteocyte numbers in the grafted necrotic bone at the 2nd and 4th weeks after surgery. In conclusion, the newly developed SPEMF accelerates osteogenic differentiation of cultured hBMSCs and enhances bone repair, neo-vascularization, and cell growth in necrotic bone in mice. The potential clinical advantage of the SPEMF is the short daily application and the shorter treatment course. We suggest that SPEMF may be used to treat fractures and the early stages of osteonecrosis.

  15. A novel single pulsed electromagnetic field stimulates osteogenesis of bone marrow mesenchymal stem cells and bone repair.

    Directory of Open Access Journals (Sweden)

    Yin-Chih Fu

    Full Text Available Pulsed electromagnetic field (PEMF has been successfully applied to accelerate fracture repair since 1979. Recent studies suggest that PEMF might be used as a nonoperative treatment for the early stages of osteonecrosis. However, PEMF treatment requires a minimum of ten hours per day for the duration of the treatment. In this study, we modified the protocol of the single-pulsed electromagnetic field (SPEMF that only requires a 3-minute daily treatment. In the in vitro study, cell proliferation and osteogenic differentiation was evaluated in the hBMSCs. In the in vivo study, new bone formation and revascularization were evaluated in the necrotic bone graft. Results from the in vitro study showed no significant cytotoxic effects on the hBMSCs after 5 days of SPEMF treatment (1 Tesla, 30 pulses per day. hBMSC proliferation was enhanced in the SPEMF-treated groups after 2 and 4 days of treatment. The osteogenic differentiation of hBMSCs was significantly increased in the SPEMF-treated groups after 3-7 days of treatment. Mineralization also increased after 10, 15, 20, and 25 days of treatment in SPEMF-treated groups compared to the control group. The 7-day short-course treatment achieved similar effects on proliferation and osteogenesis as the 25-day treatment. Results from the in vivo study also demonstrated that both the 7-day and 25-day treatments of SPEMF increased callus formation around the necrotic bone and also increased new vessel formation and osteocyte numbers in the grafted necrotic bone at the 2nd and 4th weeks after surgery. In conclusion, the newly developed SPEMF accelerates osteogenic differentiation of cultured hBMSCs and enhances bone repair, neo-vascularization, and cell growth in necrotic bone in mice. The potential clinical advantage of the SPEMF is the short daily application and the shorter treatment course. We suggest that SPEMF may be used to treat fractures and the early stages of osteonecrosis.

  16. Is CP violation maximal

    International Nuclear Information System (INIS)

    Gronau, M.

    1984-01-01

    Two ambiguities are noted in the definition of the concept of maximal CP violation. The phase convention ambiguity is overcome by introducing a CP violating phase in the quark mixing matrix U which is invariant under rephasing transformations. The second ambiguity, related to the parametrization of U, is resolved by finding a single empirically viable definition of maximal CP violation when assuming that U does not single out one generation. Considerable improvement in the calculation of nonleptonic weak amplitudes is required to test the conjecture of maximal CP violation. 21 references

  17. From single-pulsed field gradient to double-pulsed field gradient MR: gleaning new microstructural information and developing new forms of contrast in MRI.

    Science.gov (United States)

    Shemesh, Noam; Ozarslan, Evren; Komlosh, Michal E; Basser, Peter J; Cohen, Yoram

    2010-08-01

    One of the hallmarks of diffusion NMR and MRI is its ability to utilize restricted diffusion to probe compartments much smaller than the excited volume or the MRI voxel, respectively, and to extract microstructural information from them. Single-pulsed field gradient (s-PFG) MR methodologies have been employed with great success to probe microstructures in various disciplines, ranging from chemistry to neuroscience. However, s-PFG MR also suffers from inherent shortcomings, especially when specimens are characterized by orientation or size distributions: in such cases, the microstructural information available from s-PFG experiments is limited or lost. Double-pulsed field gradient (d-PFG) MR methodology, an extension of s-PFG MR, has attracted attention owing to recent theoretical studies predicting that it can overcome certain inherent limitations of s-PFG MR. In this review, we survey the microstructural features that can be obtained from conventional s-PFG methods in the different q regimes, and highlight its limitations. The experimental aspects of d-PFG methodology are then presented, together with an overview of its theoretical underpinnings and a general framework for relating the MR signal decay and material microstructure, affording new microstructural parameters. We then discuss recent studies that have validated the theory using phantoms in which the ground truth is well known a priori, a crucial step prior to the application of d-PFG methodology in neuronal tissue. The experimental findings are in excellent agreement with the theoretical predictions and reveal, inter alia, zero-crossings of the signal decay, robustness towards size distributions and angular dependences of the signal decay from which accurate microstructural parameters, such as compartment size and even shape, can be extracted. Finally, we show some initial findings in d-PFG MR imaging. This review lays the foundation for future studies, in which accurate and novel microstructural

  18. Spin and Maximal Acceleration

    Directory of Open Access Journals (Sweden)

    Giorgio Papini

    2017-12-01

    Full Text Available We study the spin current tensor of a Dirac particle at accelerations close to the upper limit introduced by Caianiello. Continual interchange between particle spin and angular momentum is possible only when the acceleration is time-dependent. This represents a stringent limit on the effect that maximal acceleration may have on spin physics in astrophysical applications. We also investigate some dynamical consequences of maximal acceleration.

  19. Maximization, learning, and economic behavior.

    Science.gov (United States)

    Erev, Ido; Roth, Alvin E

    2014-07-22

    The rationality assumption that underlies mainstream economic theory has proved to be a useful approximation, despite the fact that systematic violations to its predictions can be found. That is, the assumption of rational behavior is useful in understanding the ways in which many successful economic institutions function, although it is also true that actual human behavior falls systematically short of perfect rationality. We consider a possible explanation of this apparent inconsistency, suggesting that mechanisms that rest on the rationality assumption are likely to be successful when they create an environment in which the behavior they try to facilitate leads to the best payoff for all agents on average, and most of the time. Review of basic learning research suggests that, under these conditions, people quickly learn to maximize expected return. This review also shows that there are many situations in which experience does not increase maximization. In many cases, experience leads people to underweight rare events. In addition, the current paper suggests that it is convenient to distinguish between two behavioral approaches to improve economic analyses. The first, and more conventional approach among behavioral economists and psychologists interested in judgment and decision making, highlights violations of the rational model and proposes descriptive models that capture these violations. The second approach studies human learning to clarify the conditions under which people quickly learn to maximize expected return. The current review highlights one set of conditions of this type and shows how the understanding of these conditions can facilitate market design.

  20. Role of maximal primary cytoreductive surgery in patients with advanced epithelial ovarian and tubal cancer: Surgical and oncological outcomes. Single institution experience.

    Science.gov (United States)

    Peiretti, Michele; Zanagnolo, Vanna; Aletti, Giovanni D; Bocciolone, Luca; Colombo, Nicoletta; Landoni, Fabio; Minig, Lucas; Biffi, Roberto; Radice, Davide; Maggioni, Angelo

    2010-11-01

    To determinate the impact of maximal cytoreductive surgery on progression free survival (PFS), overall survival (OS) rates and morbidity, in patients with advanced epithelial ovarian or fallopian tube cancer. We reviewed all medical records of patients with stages IIIC-IV epithelial ovarian and fallopian tube cancer that were managed at our institution between January 2001 and December 2008. The following information was collected: demographics, tumor characteristics, operative information, surgical outcomes and peri-operative complication. A total of 288 patients with advanced epithelial ovarian and fallopian tube cancer were referred to our institution between January 2001 and December 2008, 259 consecutive patients were enrolled in the study. After a median follow-up of 29.8 months, the PFS and OS were 19.9 and 57.6 months, respectively. At univariate analysis, factors significantly associated with decreased PFS included: age greater than median (>60 years), stage IV, presence of ascites >1000 cc, presence of diffuse peritoneal carcinomatosis and diameter of residual disease. This was confirmed also at multivariate analysis with age greater than 60 years (P=0.025), stage IV vs IIIC (P=0.037) and any residual disease (P=0.032) having an independent association with worse PFS. Our study seems to demonstrate that a more extensive surgical approach is associated with prolonged disease-free interval and improved survival in patients with stages IIIC-IV epithelial ovarian and fallopian tube cancer. Moreover all patients with no residual tumor seem to have the best prognosis and in view of these results we believe that the goal of primary surgery should be considered as leaving no macroscopic disease. Copyright © 2010 Elsevier Inc. All rights reserved.

  1. Social group utility maximization

    CERN Document Server

    Gong, Xiaowen; Yang, Lei; Zhang, Junshan

    2014-01-01

    This SpringerBrief explains how to leverage mobile users' social relationships to improve the interactions of mobile devices in mobile networks. It develops a social group utility maximization (SGUM) framework that captures diverse social ties of mobile users and diverse physical coupling of mobile devices. Key topics include random access control, power control, spectrum access, and location privacy.This brief also investigates SGUM-based power control game and random access control game, for which it establishes the socially-aware Nash equilibrium (SNE). It then examines the critical SGUM-b

  2. Guinea pig maximization test

    DEFF Research Database (Denmark)

    Andersen, Klaus Ejner

    1985-01-01

    Guinea pig maximization tests (GPMT) with chlorocresol were performed to ascertain whether the sensitization rate was affected by minor changes in the Freund's complete adjuvant (FCA) emulsion used. Three types of emulsion were evaluated: the oil phase was mixed with propylene glycol, saline...... with 30% (v/v) ethanol or saline, respectively. Relative viscosity was used as one measure of physical properties of the emulsion. Higher degrees of sensitization (but not rates) were obtained at the 48 h challenge reading with the oil/propylene glycol and oil/saline + ethanol emulsions compared...

  3. Deep tissue optical imaging of upconverting nanoparticles enabled by exploiting higher intrinsic quantum yield through use of millisecond single pulse excitation with high peak power

    DEFF Research Database (Denmark)

    Liu, Haichun; Xu, Can T.; Dumlupinar, Gökhan

    2013-01-01

    the possible thermal side-effects of the excitation light moderate. These key results facilitate means to break through the general shallow depth limit of upconverting-nanoparticle-based fluorescence techniques, necessary for a range of biomedical applications, including diffuse optical imaging, photodynamic......We have accomplished deep tissue optical imaging of upconverting nanoparticles at 800 nm, using millisecond single pulse excitation with high peak power. This is achieved by carefully choosing the pulse parameters, derived from time-resolved rate-equation analysis, which result in higher intrinsic...... quantum yield that is utilized by upconverting nanoparticles for generating this near infrared upconversion emission. The pulsed excitation approach thus promises previously unreachable imaging depths and shorter data acquisition times compared with continuous wave excitation, while simultaneously keeping...

  4. Single pulse two-photon fluorescence lifetime imaging (SP-FLIM) with MHz pixel rate and an all fiber based setup

    Science.gov (United States)

    Eibl, Matthias; Karpf, Sebastian; Hakert, Hubertus; Weng, Daniel; Pfeiffer, Tom; Kolb, Jan Philip; Huber, Robert

    2017-07-01

    Newly developed microscopy methods have the goal to give researches in bio-molecular science a better understanding of processes ongoing on a cellular level. Especially two-photon excited fluorescence (TPEF) microscopy is a readily applied and widespread modality. Compared to one photon fluorescence imaging, it is possible to image not only the surface but also deeper lying structures. Together with fluorescence lifetime imaging (FLIM), which provides information on the chemical composition of a specimen, deeper insights on a molecular level can be gained. However, the need for elaborate light sources for TPEF and speed limitations for FLIM hinder an even wider application. In this contribution, we present a way to overcome this limitations by combining a robust and inexpensive fiber laser for nonlinear excitation with a fast analog digitization method for rapid FLIM imaging. The applied sub nanosecond pulsed laser source is perfectly suited for fiber delivery as typically limiting non-linear effects like self-phase or cross-phase modulation (SPM, XPM) are negligible. Furthermore, compared to the typically applied femtosecond pulses, our longer pulses produce much more fluorescence photons per single shot. In this paper, we show that this higher number of fluorescence photons per pulse combined with a high analog bandwidth detection makes it possible to not only use a single pulse per pixel for TPEF imaging but also to resolve the exponential time decay for FLIM. To evaluate our system, we acquired FLIM images of a dye solution with single exponential behavior to assess the accuracy of our lifetime determination and also FLIM images of a plant stem at a pixel rate of 1 MHz to show the speed performance of our single pulse two-photon FLIM (SP-FLIM) system.

  5. Single-pulse measurement of density and temperature in a turbulent, supersonic flow using UV laser spectroscopy

    Science.gov (United States)

    Fletcher, D. G.; Mckenzie, R. L.

    1992-01-01

    Nonintrusive measurements of density and temperature and their turbulent fluctuation levels have been obtained in the boundary layer of an unseeded, Mach 2 wind tunnel flow. The spectroscopic technique that was used to make the measurements is based on the combination of laser-induced oxygen fluorescence and Raman scattering by oxygen and nitrogen from the same laser pulse. Results from this demonstration experiment compare favorably with previous measurements obtained in the same facility from conventional probes and an earlier spectroscopic technique.

  6. MAXIMS VIOLATIONS IN LITERARY WORK

    Directory of Open Access Journals (Sweden)

    Widya Hanum Sari Pertiwi

    2015-12-01

    Full Text Available This study was qualitative research action that focuses to find out the flouting of Gricean maxims and the functions of the flouting in the tales which are included in collection of children literature entitled My Giant Treasury of Stories and Rhymes. The objective of the study is generally to identify the violation of maxims of quantity, quality, relevance, and manner in the data sources and also to analyze the use of the flouting in the tales which are included in the book. Qualitative design using categorizing strategies, specifically coding strategy, was applied. Thus, the researcher as the instrument in this investigation was selecting the tales, reading them, and gathering every item which reflects the violation of Gricean maxims based on some conditions of flouting maxims. On the basis of the data analysis, it was found that the some utterances in the tales, both narration and conversation, flouting the four maxims of conversation, namely maxim of quality, maxim of quantity, maxim of relevance, and maxim of manner. The researcher has also found that the flouting of maxims has one basic function that is to encourage the readers’ imagination toward the tales. This one basic function is developed by six others functions: (1 generating specific situation, (2 developing the plot, (3 enlivening the characters’ utterance, (4 implicating message, (5 indirectly characterizing characters, and (6 creating ambiguous setting. Keywords: children literature, tales, flouting maxims

  7. Ehrenfest's Lottery--Time and Entropy Maximization

    Science.gov (United States)

    Ashbaugh, Henry S.

    2010-01-01

    Successful teaching of the Second Law of Thermodynamics suffers from limited simple examples linking equilibrium to entropy maximization. I describe a thought experiment connecting entropy to a lottery that mixes marbles amongst a collection of urns. This mixing obeys diffusion-like dynamics. Equilibrium is achieved when the marble distribution is…

  8. Maximally Symmetric Composite Higgs Models.

    Science.gov (United States)

    Csáki, Csaba; Ma, Teng; Shu, Jing

    2017-09-29

    Maximal symmetry is a novel tool for composite pseudo Goldstone boson Higgs models: it is a remnant of an enhanced global symmetry of the composite fermion sector involving a twisting with the Higgs field. Maximal symmetry has far-reaching consequences: it ensures that the Higgs potential is finite and fully calculable, and also minimizes the tuning. We present a detailed analysis of the maximally symmetric SO(5)/SO(4) model and comment on its observational consequences.

  9. Maxims for Humanizing Education

    Science.gov (United States)

    Rossiter, Charles M., Jr.

    1976-01-01

    A review of humanistic psychology literature by the author leads him to specify five major elements of a humanistic orientation. It is concluded that it is the teacher's orientation, rather than any specific technique, which is the significant determinant of whether or not the classroom experience will have a humanistic orientation. For journal…

  10. Maximizing entropy over Markov processes

    DEFF Research Database (Denmark)

    Biondi, Fabrizio; Legay, Axel; Nielsen, Bo Friis

    2014-01-01

    computation reduces to finding a model of a specification with highest entropy. Entropy maximization for probabilistic process specifications has not been studied before, even though it is well known in Bayesian inference for discrete distributions. We give a characterization of global entropy of a process...... as a reward function, a polynomial algorithm to verify the existence of a system maximizing entropy among those respecting a specification, a procedure for the maximization of reward functions over Interval Markov Chains and its application to synthesize an implementation maximizing entropy. We show how...

  11. Maximizing Entropy over Markov Processes

    DEFF Research Database (Denmark)

    Biondi, Fabrizio; Legay, Axel; Nielsen, Bo Friis

    2013-01-01

    computation reduces to finding a model of a specification with highest entropy. Entropy maximization for probabilistic process specifications has not been studied before, even though it is well known in Bayesian inference for discrete distributions. We give a characterization of global entropy of a process...... as a reward function, a polynomial algorithm to verify the existence of an system maximizing entropy among those respecting a specification, a procedure for the maximization of reward functions over Interval Markov Chains and its application to synthesize an implementation maximizing entropy. We show how...

  12. Principles of maximally classical and maximally realistic quantum ...

    Indian Academy of Sciences (India)

    Principles of maximally classical and maximally realistic quantum mechanics. S M ROY. Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400 005, India. Abstract. Recently Auberson, Mahoux, Roy and Singh have proved a long standing conjecture of Roy and Singh: In 2N-dimensional phase space, ...

  13. Assessment of Event-Related EEG Power After Single-Pulse TMS in Unresponsive Wakefulness Syndrome and Minimally Conscious State Patients.

    Science.gov (United States)

    Formaggio, Emanuela; Cavinato, Marianna; Storti, Silvia Francesca; Tonin, Paolo; Piccione, Francesco; Manganotti, Paolo

    2016-03-01

    In patients without a behavioral response, non-invasive techniques and new methods of data analysis can complement existing diagnostic tools by providing a method for detecting covert signs of residual cognitive function and awareness. The aim of this study was to investigate the brain oscillatory activities synchronized by single-pulse transcranial magnetic stimulation (TMS) delivered over the primary motor area in the time-frequency domain in patients with the unresponsive wakefulness syndrome or in a minimally conscious state as compared to healthy controls. A time-frequency analysis based on the wavelet transform was used to characterize rapid modifications of oscillatory EEG rhythms induced by TMS in patients as compared to healthy controls. The pattern of EEG changes in the patients differed from that of healthy controls. In the controls there was an early synchronization of slow waves immediately followed by a desynchronization of alpha and beta frequency bands over the frontal and centro-parietal electrodes, whereas an opposite early synchronization, particularly over motor areas for alpha and beta and over the frontal and parietal electrodes for beta power, was seen in the patients. In addition, no relevant modification in slow rhythms (delta and theta) after TMS was noted in patients. The clinical impact of these findings could be relevant in neurorehabilitation settings for increasing the awareness of these patients and defining new treatment procedures.

  14. Kinetics of the Thermal Decomposition of Tetramethylsilane behind the Reflected Shock Waves in a Single Pulse Shock Tube (SPST) and Modeling Study

    Science.gov (United States)

    Parandaman, A.; Sudhakar, G.; Rajakumar, B.

    Thermal reactions of Tetramethylsilane (TMS) diluted in argon were studied behind the reflected shock waves in a single-pulse shock tube (SPST) over the temperature range of 1085-1221 K and pressures varied between 10.6 and 22.8 atm. The stable products resulting from the decomposition of TMS were identified and quantified using gas chromatography and also verified with Fourier Transform Infrared (FTIR) spectrometer. The major reaction products are methane (CH4) and ethylene (C2H4). The minor reaction products are ethane (C2H6) and propylene (C3H6). The initiation of mechanism in the decomposition of TMS takes plays via the Si-C bond scission by ejecting the methyl radicals (CH3) and trimethylsilyl radicals ((CH3)3Si). The measured temperature dependent rate coefficient for the total decomposition of TMS was to be ktotal = 1.66 ×1015 exp (-64.46/RT) s-1 and for the formation of CH4 reaction channel was to be k = 2.20 × 1014 exp (-60.15/RT) s-1, where the activation energies are given in kcal mol-1. A kinetic scheme containing 17 species and 28 elementary reactions was used for the simulation using chemical kinetic simulator over the temperature range of 1085-1221 K. The agreement between the experimental and simulated results was satisfactory.

  15. Study of single pulsed-field magnetization of Gd-Ba-Cu-O bulk high-temperature superconductor with a split type of armature coil for rotating machinery

    International Nuclear Information System (INIS)

    Morita, E; Matsuzaki, H; Kimura, Y; Ohtani, I; Ogata, H; Izumi, M; Nonaka, Y; Murakami, M; Ida, T; Sugimoto, H; Miki, M; Kitano, M

    2006-01-01

    We employed a Gd-bulk HTS as rotating field magnet poles aiming for a smaller and lighter axial-gap-type motor. The bulk was inserted in the split-type armature pulsed copper coils and cooled down to 77 K under zero field. Employing the bulk magnet to HTS rotating machinery, the number of pulsed field magnetizations should be reduced for practical use. Thereby, a single pulsed current was applied to the pulsed copper coils to magnetize the bulk. The trapped field distribution and transient flux behaviour strongly depend on the radial dimension of the armature coil with a vortex-type winding. On decreasing the diameter of the pulsed copper armature coil, the distribution of the trapped flux density on the surface of the bulk becomes close to a conical shape. In contrast to the use of a solenoid, the application of vortex-type armature coils to magnetization of Gd-bulk HTS shows a quick intervention of the external magnetic flux into the centre of the bulk. The magnetization to the bulk HTS of the vortex-type copper coils with an optimum radius is useful and may be an effective technique for applied bulk HTS for rotating machines such as motors and/or generators

  16. Towards diffractive imaging with single pulses of FEL radiation. Dynamics within irradiatied samples and their influence on the analysis of imaging data

    International Nuclear Information System (INIS)

    Wang, Fenglin

    2010-08-01

    3D single particle coherent diffraction imaging (CDI) of bioparticles (such as proteins, macromolecules and viruses) is one of the main possible applications of the new generation of light sources: free-electron lasers (FELs), which are now available at FLASH (Hamburg, Germany) and LCLS (Stanford, U.S.A.). The extremely bright and ultrashort FEL pulses potentially enable CDI to achieve high resolution down to subnanometer length scale. However, intense FEL pulses cause serious radiation damage in bioparticles, even during single shots, which may set the resolution limits for CDI with FELs. Currently, since the signal-to-noise ratio is very low for small biological particles, direct experimental study of radiation damage in the single particle imaging is fairly difficult. Single atomic (noble gas) clusters become good objects to reveal effects of radiation damage processes on CDI with FEL radiation. This thesis studies three aspects of the radiation damage problem, which are treated in three independent chapters: (1) Molecular Dynamics simulations to quantitively describe radiation damage processes within irradiated atomic clusters during single pulses; (2) reconstruction analysis of single-shot CDI diffraction patterns of atomic clusters, which may potentially help to understand the radiation damage occurring in biological samples; and (3) testing the effects of coating water layers in CDI, which is supposed to minimize the radiation damage in irradiated bioparticles. (orig.)

  17. A Study of Cortical Excitability, Central Motor Conduction, and Cortical Inhibition Using Single Pulse Transcranial Magnetic Stimulation in Patients with Early Frontotemporal and Alzheimer's Dementia.

    Science.gov (United States)

    Chandra, Sadanandavalli Retnaswami; Issac, Thomas Gregor; Nagaraju, B C; Philip, Mariamma

    2016-01-01

    Degenerative cortical dementias affect several million people worldwide. Early diagnosis and categorization are essential for initiating appropriate pharmacological and nonpharmacological treatment so that deterioration can be postponed, and disability adjusted life years can be saved both for the patient and for the caregiver. Therefore, an early, simple, noninvasive biomarker will serve as a boon. Patients who satisfied probable Alzheimer's disease (AD) or frontotemporal dementia (FTD) using international consensus criteria for FTD and National Institute of Neurological Disorders and Stroke-AD and Related Disorders Association criteria for AD were evaluated using single pulse transcranial magnetic stimulation with figure of eight coil and motor evoked potential from right first dorsal interossei. Resting threshold (MT), central motor conduction time (CMCT), and silent period (SP) were evaluated. Resting MT and SP are reduced in patients with Alzheimer's disease whereas CMCT is prolonged in patients with FTD and SP is in the lower limit of normal in both conditions. The patterns of central motor conduction and MT are distinctly different in patients with early Alzheimer's disease (AD) and FTD.

  18. A Comparative Study of Single-pulse and Double-pulse Laser-Induced Breakdown Spectroscopy with Uranium-containing Samples.

    Science.gov (United States)

    Skrodzki, Patrick J; Becker, Jason R; Diwakar, Prasoon K; Harilal, Sivanandan S; Hassanein, Ahmed

    2016-03-01

    Laser-induced breakdown spectroscopy (LIBS) holds potential advantages in special nuclear material (SNM) sensing and nuclear forensics, which require rapid analysis, minimal sample preparation, and stand-off distance capability. SNM, such as U, however, result in crowded emission spectra with LIBS, and characteristic emission lines are challenging to discern. It is well-known that double-pulse LIBS (DPLIBS) improves the signal intensity for analytes over conventional single-pulse LIBS (SPLIBS). This study investigates the U signal in a glass matrix using DPLIBS and compares it to signal obtained using SPLIBS. Double-pulse LIBS involves sequential firing of a 1.06 µm Nd:YAG pre-pulse and 10.6 µm TEA CO2 heating pulse in a near collinear geometry. Optimization of experimental parameters including inter-pulse delay and energy follows identification of characteristic lines for the bulk analyte Ca and the minor constituent analyte U for both DPLIBS and SPLIBS. Spatial and temporal coupling of the two pulses in the proposed DPLIBS technique yields improvements in analytical merits with a negligible increase in damage to the sample compared to SPLIBS. Subsequently, the study discusses optimum plasma emission conditions of U lines and relative figures of merit in both SPLIBS and DPLIBS. Investigation into plasma characteristics also addresses plausible mechanisms related to the observed U analyte signal variation between SPLIBS and DPLIBS. © The Author(s) 2016.

  19. Towards diffractive imaging with single pulses of FEL radiation. Dynamics within irradiatied samples and their influence on the analysis of imaging data

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Fenglin

    2010-08-15

    3D single particle coherent diffraction imaging (CDI) of bioparticles (such as proteins, macromolecules and viruses) is one of the main possible applications of the new generation of light sources: free-electron lasers (FELs), which are now available at FLASH (Hamburg, Germany) and LCLS (Stanford, U.S.A.). The extremely bright and ultrashort FEL pulses potentially enable CDI to achieve high resolution down to subnanometer length scale. However, intense FEL pulses cause serious radiation damage in bioparticles, even during single shots, which may set the resolution limits for CDI with FELs. Currently, since the signal-to-noise ratio is very low for small biological particles, direct experimental study of radiation damage in the single particle imaging is fairly difficult. Single atomic (noble gas) clusters become good objects to reveal effects of radiation damage processes on CDI with FEL radiation. This thesis studies three aspects of the radiation damage problem, which are treated in three independent chapters: (1) Molecular Dynamics simulations to quantitively describe radiation damage processes within irradiated atomic clusters during single pulses; (2) reconstruction analysis of single-shot CDI diffraction patterns of atomic clusters, which may potentially help to understand the radiation damage occurring in biological samples; and (3) testing the effects of coating water layers in CDI, which is supposed to minimize the radiation damage in irradiated bioparticles. (orig.)

  20. A maximal atmospheric mixing from a maximal CP violating phase

    Energy Technology Data Exchange (ETDEWEB)

    Masina, Isabella [Centro Studi e Ricerche ' E. Fermi' , Via Panisperna 89/A, Rome (Italy) and INFN, Sezione di Roma, P.le A. Moro 2, Rome (Italy)]. E-mail: isabella.masina@roma1.infn.it

    2006-02-02

    We point out an elegant mechanism to predict a maximal atmospheric angle, which is based on a maximal CP violating phase difference between second and third lepton families in the flavour symmetry basis. In this framework, a discussion of the general formulas for {theta}{sub 12}, vertical bar U{sub e3} vertical bar, {delta} and their possible correlations in some limiting cases is provided. We also present an explicit realisation in terms of an SO(3) flavour symmetry model.

  1. Some feature of interpretation of tension single pulsed electromagnetic field of the Earth to create the model parameter fields physical properties

    Directory of Open Access Journals (Sweden)

    Mokritskaya T.P.

    2014-12-01

    Full Text Available Stochastic analysis of the results of different methods of obtaining and processing of information allows us to solve problems on a qualitatively different level. This is important when creating complex earth models and fields of its parameters, particularly the physical properties. Application of remote sensing methods (geophysical investigations with the registration of a single pulse intensity of the electromagnetic field of the Earth (EIEMPZ seismic profiling, is expanding. Interesting results of the joint interpretation of the results of geophysical and laboratory studies of physical soil. Interesting results of the joint interpretation of the results of geophysical and laboratory studies of physical soil. For the first time a methodology for assessing the state of the soil [3] applied for a joint interpretation of materials determine the field strength EMPZ, seismic profiling, and laboratory techniques. This has allowed to characterize the state of the geological environment and to build a model of inhomogeneous density distribution of fractured rocks at depth. In this paper we made a mathematical analysis of the results of research and talus deposits eluvial clay Taurian series, studied at one of the construction sites southern coast at a depth of 12.0 -25.0 m. Methods of statistical analysis, assessment of homogeneity and symmetrically distributed, rank correlation and multiple regression analysis described in [3]. The analysis of the spatial distribution of areas extrem value of EMPZ, heterogeneity of seismic rigidity. Statistical characteristics of indicators of physical properties reflect the genetic characteristics of the formation and the current state of silty-clay sediments of different genesis.It is proved that the regression model can be applied to interpret the state of the array in the construction of geodynamic model. It is established that the creation of forward-looking (dynamic models for the distribution of the physical

  2. Maximization

    OpenAIRE

    A. Garmroodi Asil; A. Shahsavand; Sh. Mirzaei

    2017-01-01

    Over 60% of Iranian natural gases are contaminated with hydrogen sulfide or other sulfur compounds. Khangiran refinery which receives around 50 MMSCMD sour gas with 3.35 mol% H2S as its GTU feed, produces around 45% of Iranian sulfur production. Three of the four existing sulfur recovery units (SRU’s) are initially installed more than 3 decades ago. Such relatively old Claus units with no tail gas clean up facility have usually sulfur recovery efficiencies as low as 90%, due to the low H2S co...

  3. Maximization

    Directory of Open Access Journals (Sweden)

    A. Garmroodi Asil

    2017-09-01

    To further reduce the sulfur dioxide emission of the entire refining process, two scenarios of acid gas or air preheats are investigated when either of them is used simultaneously with the third enrichment scheme. The maximum overall sulfur recovery efficiency and highest combustion chamber temperature is slightly higher for acid gas preheats but air preheat is more favorable because it is more benign. To the best of our knowledge, optimization of the entire GTU + enrichment section and SRU processes has not been addressed previously.

  4. Principles of maximally classical and maximally realistic quantum ...

    Indian Academy of Sciences (India)

    so different from the classical trajectories that they are sometimes called surrealistic [4]!. The answer to the first problem above is in the construction of maximally realistic quan- tum mechanics [5,6] which treats position and momentum symmetrically. We present in this paper the answer to the second problem in the form of a ...

  5. Principles of maximally classical and maximally realistic quantum

    Indian Academy of Sciences (India)

    Recently Auberson, Mahoux, Roy and Singh have proved a long standing conjecture of Roy and Singh: In 2-dimensional phase space, a maximally realistic quantum mechanics can have quantum probabilities of no more than + 1 complete commuting cets (CCS) of observables coexisting as marginals of one positive ...

  6. Principles of maximally classical and maximally realistic quantum ...

    Indian Academy of Sciences (India)

    Recently Auberson, Mahoux, Roy and Singh have proved a long standing conjecture of Roy and Singh: In 2-dimensional phase space, a maximally realistic quantum mechanics can have quantum probabilities of no more than + 1 complete commuting cets (CCS) of observables coexisting as marginals of one positive ...

  7. Finding Maximal Quasiperiodicities in Strings

    DEFF Research Database (Denmark)

    Brodal, Gerth Stølting; Pedersen, Christian N. S.

    2000-01-01

    of length n in time O(n log n) and space O(n). Our algorithm uses the suffix tree as the fundamental data structure combined with efficient methods for merging and performing multiple searches in search trees. Besides finding all maximal quasiperiodic substrings, our algorithm also marks the nodes...... in the suffix tree that have a superprimitive path-label....

  8. Maximal Linear Embedding for Dimensionality Reduction.

    Science.gov (United States)

    Wang, Ruiping; Shan, Shiguang; Chen, Xilin; Chen, Jie; Gao, Wen

    2011-09-01

    Over the past few decades, dimensionality reduction has been widely exploited in computer vision and pattern analysis. This paper proposes a simple but effective nonlinear dimensionality reduction algorithm, named Maximal Linear Embedding (MLE). MLE learns a parametric mapping to recover a single global low-dimensional coordinate space and yields an isometric embedding for the manifold. Inspired by geometric intuition, we introduce a reasonable definition of locally linear patch, Maximal Linear Patch (MLP), which seeks to maximize the local neighborhood in which linearity holds. The input data are first decomposed into a collection of local linear models, each depicting an MLP. These local models are then aligned into a global coordinate space, which is achieved by applying MDS to some randomly selected landmarks. The proposed alignment method, called Landmarks-based Global Alignment (LGA), can efficiently produce a closed-form solution with no risk of local optima. It just involves some small-scale eigenvalue problems, while most previous aligning techniques employ time-consuming iterative optimization. Compared with traditional methods such as ISOMAP and LLE, our MLE yields an explicit modeling of the intrinsic variation modes of the observation data. Extensive experiments on both synthetic and real data indicate the effectivity and efficiency of the proposed algorithm.

  9. FLOUTING MAXIMS IN INDONESIA LAWAK KLUB CONVERSATION

    Directory of Open Access Journals (Sweden)

    Rahmawati Sukmaningrum

    2017-04-01

    Full Text Available This study aims to identify the types of maxims flouted in the conversation in famous comedy show, Indonesia Lawak Club. Likewise, it also tries to reveal the speakers‘ intention of flouting the maxim in the conversation during the show. The writers use descriptive qualitative method in conducting this research. The data is taken from the dialogue of Indonesia Lawak club and then analyzed based on Grice‘s cooperative principles. The researchers read the dialogue‘s transcripts, identify the maxims, and interpret the data to find the speakers‘ intention for flouting the maxims in the communication. The results show that there are four types of maxims flouted in the dialogue. Those are maxim of quality (23%, maxim of quantity (11%, maxim of manner (31%, and maxim of relevance (35. Flouting the maxims in the conversations is intended to make the speakers feel uncomfortable with the conversation, show arrogances, show disagreement or agreement, and ridicule other speakers.

  10. Frequência cardíaca máxima: influência da experiência desportiva na infância e adolescência Maximal heart rate: influence of sport practice during childhood and adolescence

    Directory of Open Access Journals (Sweden)

    Débora Helena Balassiano

    2013-04-01

    Full Text Available FUNDAMENTO: A Frequência Cardíaca (FC alcançada ao final de um teste de exercício (TE é denominada FC máxima e possui reconhecida relevância clínica e epidemiológica. Para sua medida correta é necessário que o TE seja verdadeiramente máximo. OBJETIVO: Avaliar a influência do histórico de exercício físico intenso e/ou participação desportiva competitiva na juventude sobre a FC máxima (% da prevista pela idade em um teste cardiopulmonar de exercício (TCPE clínico. MÉTODOS: Foram selecionados retrospectivamente 600 indivíduos não atletas (65,8% homens com idade de 46 ± 13,7 anos, em prevenção primária de doenças cardiovasculares, submetidos a um TCPE máximo. O perfil de exercício físico na infância/adolescência (PEFIA foi classificado em escores crescentes de 0 a 4, com o valor 2 correspondendo aos níveis esperados para a faixa etária. RESULTADOS: Dentre os 20 indivíduos com valores de FC máxima igual ou maior do que 200 bpm, nenhum deles tinha sido inativo ou pouco ativo na infância/adolescência. Houve uma associação significativa entre escores de PEFIA e a FC máxima (% da prevista pela idade (p = 0,02, com um valor de 7 bpm mais alto para os escores de PEFIA 3-4 (32,9% da amostra quando comparados com 0-2. CONCLUSÃO: Duas hipóteses surgem para explicar esses resultados nos indivíduos mais ativos na juventude: a persistência de adaptações crônicas do treinamento sobre o cronotropismo cardíaco ou b maior capacidade e/ou motivação para alcançar um TCPE verdadeiramente máximo. Questionar sobre o perfil de exercício físico na infância/adolescência pode contribuir para a interpretação da FC máxima no TE.BACKGROUND: The heart rate (HR achieved at the end of an exercise test (ET is called maximal HR and is known to have clinical and epidemiological relevance. For its correct measurement, it is necessary that the ET be truly maximal. OBJECTIVE: To evaluate the influence of a history of intense

  11. Maximal abelian sets of roots

    CERN Document Server

    Lawther, R

    2018-01-01

    In this work the author lets \\Phi be an irreducible root system, with Coxeter group W. He considers subsets of \\Phi which are abelian, meaning that no two roots in the set have sum in \\Phi \\cup \\{ 0 \\}. He classifies all maximal abelian sets (i.e., abelian sets properly contained in no other) up to the action of W: for each W-orbit of maximal abelian sets we provide an explicit representative X, identify the (setwise) stabilizer W_X of X in W, and decompose X into W_X-orbits. Abelian sets of roots are closely related to abelian unipotent subgroups of simple algebraic groups, and thus to abelian p-subgroups of finite groups of Lie type over fields of characteristic p. Parts of the work presented here have been used to confirm the p-rank of E_8(p^n), and (somewhat unexpectedly) to obtain for the first time the 2-ranks of the Monster and Baby Monster sporadic groups, together with the double cover of the latter. Root systems of classical type are dealt with quickly here; the vast majority of the present work con...

  12. Maximal Abelian sets of roots

    CERN Document Server

    Lawther, R

    2018-01-01

    In this work the author lets \\Phi be an irreducible root system, with Coxeter group W. He considers subsets of \\Phi which are abelian, meaning that no two roots in the set have sum in \\Phi \\cup \\{ 0 \\}. He classifies all maximal abelian sets (i.e., abelian sets properly contained in no other) up to the action of W: for each W-orbit of maximal abelian sets we provide an explicit representative X, identify the (setwise) stabilizer W_X of X in W, and decompose X into W_X-orbits. Abelian sets of roots are closely related to abelian unipotent subgroups of simple algebraic groups, and thus to abelian p-subgroups of finite groups of Lie type over fields of characteristic p. Parts of the work presented here have been used to confirm the p-rank of E_8(p^n), and (somewhat unexpectedly) to obtain for the first time the 2-ranks of the Monster and Baby Monster sporadic groups, together with the double cover of the latter. Root systems of classical type are dealt with quickly here; the vast majority of the present work con...

  13. Single-pulse Raman and photoacoustic spectroscopy studies of triaminotrinitrobenzene (TATB) and related compounds. [Trinitrobenzene (TNB), 1-amino-2,4,6-trinitrobenzene(MATB), 1,3-diamino-2,4,6-trinitrobenzene (DATB)

    Energy Technology Data Exchange (ETDEWEB)

    Trott, W.M.; Renlund, A.M.; Jungst, R.G.

    1985-01-01

    Pulsed-laser-excited Raman scattering methods and photoacoustic spectroscopy have been applied to the study of porous, granular samples (i.e., pressed pellets) of 1,3,5-trinitrobenzene (TNB), 1-amino-2,4,6-trinitrobenzene (MATB), 1,3-diamino-2,4,6-trinitrobenzene (DATB) and 1,3,5-triamino-2,4,6-trinitrobenzene (TATB). Single-pulse spontaneous Raman spectra have been obtained for all four materials. Using 532-nm excitation, the intensity of the background emission observed with the Raman scattered light varies as TNB > MATB > DATB > TATB. This trend is compared to information on the long-wavelength absorption edge of MATB, DATB and TATB as determined by the photoacoustic spectra of these materials. Stimulated Raman scattering has been observed for three of the compounds with conversion efficiency as follows: DATB > TATB > MATB. In the case of TATB, this process may be limited by photo-induced chemical reactions. The relatively efficient formation of one or more stable photolysis products in TATB is evident on the basis of its photoacoustic spectrum. Preliminary single-pulse Raman scattering measurements on shocked TATB are also described. 16 references, 13 figures, 2 tables.

  14. The maximal D = 4 supergravities

    Energy Technology Data Exchange (ETDEWEB)

    Wit, Bernard de [Institute for Theoretical Physics and Spinoza Institute, Utrecht University, Postbus 80.195, NL-3508 TD Utrecht (Netherlands); Samtleben, Henning [Laboratoire de Physique, ENS Lyon, 46 allee d' Italie, F-69364 Lyon CEDEX 07 (France); Trigiante, Mario [Dept. of Physics, Politecnico di Torino, Corso Duca degli Abruzzi 24, I-10129 Turin (Italy)

    2007-06-15

    All maximal supergravities in four space-time dimensions are presented. The ungauged Lagrangians can be encoded in an E{sub 7(7)}-Sp(56; R)/GL(28) matrix associated with the freedom of performing electric/magnetic duality transformations. The gauging is defined in terms of an embedding tensor {theta} which encodes the subgroup of E{sub 7(7)} that is realized as a local invariance. This embedding tensor may imply the presence of magnetic charges which require corresponding dual gauge fields. The latter can be incorporated by using a recently proposed formulation that involves tensor gauge fields in the adjoint representation of E{sub 7(7)}. In this formulation the results take a universal form irrespective of the electric/magnetic duality basis. We present the general class of supersymmetric and gauge invariant Lagrangians and discuss a number of applications.

  15. Maximizing benefits from resource development

    International Nuclear Information System (INIS)

    Skjelbred, B.

    2002-01-01

    The main objectives of Norwegian petroleum policy are to maximize the value creation for the country, develop a national oil and gas industry, and to be at the environmental forefront of long term resource management and coexistence with other industries. The paper presents a graph depicting production and net export of crude oil for countries around the world for 2002. Norway produced 3.41 mill b/d and exported 3.22 mill b/d. Norwegian petroleum policy measures include effective regulation and government ownership, research and technology development, and internationalisation. Research and development has been in five priority areas, including enhanced recovery, environmental protection, deep water recovery, small fields, and the gas value chain. The benefits of internationalisation includes capitalizing on Norwegian competency, exploiting emerging markets and the assurance of long-term value creation and employment. 5 figs

  16. VIOLATION OF CONVERSATION MAXIM ON TV ADVERTISEMENTS

    Directory of Open Access Journals (Sweden)

    Desak Putu Eka Pratiwi

    2015-07-01

    Full Text Available Maxim is a principle that must be obeyed by all participants textually and interpersonally in order to have a smooth communication process. Conversation maxim is divided into four namely maxim of quality, maxim of quantity, maxim of relevance, and maxim of manner of speaking. Violation of the maxim may occur in a conversation in which the information the speaker has is not delivered well to his speaking partner. Violation of the maxim in a conversation will result in an awkward impression. The example of violation is the given information that is redundant, untrue, irrelevant, or convoluted. Advertisers often deliberately violate the maxim to create unique and controversial advertisements. This study aims to examine the violation of maxims in conversations of TV ads. The source of data in this research is food advertisements aired on TV media. Documentation and observation methods are applied to obtain qualitative data. The theory used in this study is a maxim theory proposed by Grice (1975. The results of the data analysis are presented with informal method. The results of this study show an interesting fact that the violation of maxim in a conversation found in the advertisement exactly makes the advertisements very attractive and have a high value.

  17. A Maximally Supersymmetric Kondo Model

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, Sarah; Kachru, Shamit; Torroba, Gonzalo; /Stanford U., Phys. Dept. /SLAC

    2012-02-17

    We study the maximally supersymmetric Kondo model obtained by adding a fermionic impurity to N = 4 supersymmetric Yang-Mills theory. While the original Kondo problem describes a defect interacting with a free Fermi liquid of itinerant electrons, here the ambient theory is an interacting CFT, and this introduces qualitatively new features into the system. The model arises in string theory by considering the intersection of a stack of M D5-branes with a stack of N D3-branes, at a point in the D3 worldvolume. We analyze the theory holographically, and propose a dictionary between the Kondo problem and antisymmetric Wilson loops in N = 4 SYM. We perform an explicit calculation of the D5 fluctuations in the D3 geometry and determine the spectrum of defect operators. This establishes the stability of the Kondo fixed point together with its basic thermodynamic properties. Known supergravity solutions for Wilson loops allow us to go beyond the probe approximation: the D5s disappear and are replaced by three-form flux piercing a new topologically non-trivial S3 in the corrected geometry. This describes the Kondo model in terms of a geometric transition. A dual matrix model reflects the basic properties of the corrected gravity solution in its eigenvalue distribution.

  18. Maximizing the optical network capacity.

    Science.gov (United States)

    Bayvel, Polina; Maher, Robert; Xu, Tianhua; Liga, Gabriele; Shevchenko, Nikita A; Lavery, Domaniç; Alvarado, Alex; Killey, Robert I

    2016-03-06

    Most of the digital data transmitted are carried by optical fibres, forming the great part of the national and international communication infrastructure. The information-carrying capacity of these networks has increased vastly over the past decades through the introduction of wavelength division multiplexing, advanced modulation formats, digital signal processing and improved optical fibre and amplifier technology. These developments sparked the communication revolution and the growth of the Internet, and have created an illusion of infinite capacity being available. But as the volume of data continues to increase, is there a limit to the capacity of an optical fibre communication channel? The optical fibre channel is nonlinear, and the intensity-dependent Kerr nonlinearity limit has been suggested as a fundamental limit to optical fibre capacity. Current research is focused on whether this is the case, and on linear and nonlinear techniques, both optical and electronic, to understand, unlock and maximize the capacity of optical communications in the nonlinear regime. This paper describes some of them and discusses future prospects for success in the quest for capacity. © 2016 The Authors.

  19. Outcome Additivity and Outcome Maximality Influence Cue Competition in Human Causal Learning

    Science.gov (United States)

    Beckers, Tom; De Houwer, Jan; Pineno, Oskar; Miller, Ralph R.

    2005-01-01

    Recent research suggests that outcome additivity pretraining modulates blocking in human causal learning. However, the existing evidence confounds outcome additivity and outcome maximality. Here the authors present evidence for the influence of presenting information about outcome maximality (Experiment 1) and outcome additivity (Experiment 2) on…

  20. Stewart's maxims: eight "do's" for successfully communicating silviculture to policymakers

    Science.gov (United States)

    R. E. Stewart

    1997-01-01

    Technical specialists may experience difficulties in presenting information to non-technical policymakers and having that information used. Eight maxims are discussed that should help the silviculturist successfully provide technical information to non-technical audiences so that it will be considered in the formulation of policy.

  1. Twitch interpolation technique in testing of maximal muscle strength

    DEFF Research Database (Denmark)

    Bülow, P M; Nørregaard, J; Danneskiold-Samsøe, B

    1993-01-01

    The aim was to study the methodological aspects of the muscle twitch interpolation technique in estimating the maximal force of contraction in the quadriceps muscle utilizing commercial muscle testing equipment. Six healthy subjects participated in seven sets of experiments testing the effects...

  2. Does mental exertion alter maximal muscle activation?

    Directory of Open Access Journals (Sweden)

    Vianney eRozand

    2014-09-01

    Full Text Available Mental exertion is known to impair endurance performance, but its effects on neuromuscular function remain unclear. The purpose of this study was to test the hypothesis that mental exertion reduces torque and muscle activation during intermittent maximal voluntary contractions of the knee extensors. Ten subjects performed in a randomized order three separate mental exertion conditions lasting 27 minutes each: i high mental exertion (incongruent Stroop task, ii moderate mental exertion (congruent Stroop task, iii low mental exertion (watching a movie. In each condition, mental exertion was combined with ten intermittent maximal voluntary contractions of the knee extensor muscles (one maximal voluntary contraction every 3 minutes. Neuromuscular function was assessed using electrical nerve stimulation. Maximal voluntary torque, maximal muscle activation and other neuromuscular parameters were similar across mental exertion conditions and did not change over time. These findings suggest that mental exertion does not affect neuromuscular function during intermittent maximal voluntary contractions of the knee extensors.

  3. Inclusive Fitness Maximization:An Axiomatic Approach

    OpenAIRE

    Okasha, Samir; Weymark, John; Bossert, Walter

    2014-01-01

    Kin selection theorists argue that evolution in social contexts will lead organisms to behave as if maximizing their inclusive, as opposed to personal, fitness. The inclusive fitness concept allows biologists to treat organisms as akin to rational agents seeking to maximize a utility function. Here we develop this idea and place it on a firm footing by employing a standard decision-theoretic methodology. We show how the principle of inclusive fitness maximization and a related principle of qu...

  4. Quantum speedup in solving the maximal-clique problem

    Science.gov (United States)

    Chang, Weng-Long; Yu, Qi; Li, Zhaokai; Chen, Jiahui; Peng, Xinhua; Feng, Mang

    2018-03-01

    The maximal-clique problem, to find the maximally sized clique in a given graph, is classically an NP-complete computational problem, which has potential applications ranging from electrical engineering, computational chemistry, and bioinformatics to social networks. Here we develop a quantum algorithm to solve the maximal-clique problem for any graph G with n vertices with quadratic speedup over its classical counterparts, where the time and spatial complexities are reduced to, respectively, O (√{2n}) and O (n2) . With respect to oracle-related quantum algorithms for the NP-complete problems, we identify our algorithm as optimal. To justify the feasibility of the proposed quantum algorithm, we successfully solve a typical clique problem for a graph G with two vertices and one edge by carrying out a nuclear magnetic resonance experiment involving four qubits.

  5. Financial Management Practices, Wealth Maximization Criterion and ...

    African Journals Online (AJOL)

    In the field of financial management, shareholders wealth maximization is often seen as the desirable goal not only from the shareholders perspective but for the society at large; with the firm's primary goal aimed mainly at maximizing the wealth of its shareholders. This study thus aimed at determining the impact of the core ...

  6. Maximally differential ideals in regular local rings

    Indian Academy of Sciences (India)

    may either be maximally differential under a set of derivations or a set of higher derivations,. i.e, Hasse–Schmidt derivations. We also extend our result (Theorem 4 of [7]) about the structure of a maximally differ- ential ideal in positive characteristic to unequal characteristic case. 2. Results. By a ring we mean a commutative ...

  7. Inclusive fitness maximization: An axiomatic approach.

    Science.gov (United States)

    Okasha, Samir; Weymark, John A; Bossert, Walter

    2014-06-07

    Kin selection theorists argue that evolution in social contexts will lead organisms to behave as if maximizing their inclusive, as opposed to personal, fitness. The inclusive fitness concept allows biologists to treat organisms as akin to rational agents seeking to maximize a utility function. Here we develop this idea and place it on a firm footing by employing a standard decision-theoretic methodology. We show how the principle of inclusive fitness maximization and a related principle of quasi-inclusive fitness maximization can be derived from axioms on an individual׳s 'as if preferences' (binary choices) for the case in which phenotypic effects are additive. Our results help integrate evolutionary theory and rational choice theory, help draw out the behavioural implications of inclusive fitness maximization, and point to a possible way in which evolution could lead organisms to implement it. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. Maximal Entanglement in High Energy Physics

    Directory of Open Access Journals (Sweden)

    Alba Cervera-Lierta, José I. Latorre, Juan Rojo, Luca Rottoli

    2017-11-01

    Full Text Available We analyze how maximal entanglement is generated at the fundamental level in QED by studying correlations between helicity states in tree-level scattering processes at high energy. We demonstrate that two mechanisms for the generation of maximal entanglement are at work: i $s$-channel processes where the virtual photon carries equal overlaps of the helicities of the final state particles, and ii the indistinguishable superposition between $t$- and $u$-channels. We then study whether requiring maximal entanglement constrains the coupling structure of QED and the weak interactions. In the case of photon-electron interactions unconstrained by gauge symmetry, we show how this requirement allows reproducing QED. For $Z$-mediated weak scattering, the maximal entanglement principle leads to non-trivial predictions for the value of the weak mixing angle $\\theta_W$. Our results are a first step towards understanding the connections between maximal entanglement and the fundamental symmetries of high-energy physics.

  9. Maximizing binding capacity for protein A chromatography.

    Science.gov (United States)

    Ghose, Sanchayita; Zhang, Jennifer; Conley, Lynn; Caple, Ryan; Williams, Kevin P; Cecchini, Douglas

    2014-01-01

    Advances in cell culture expression levels in the last two decades have resulted in monoclonal antibody titers of ≥10 g/L to be purified downstream. A high capacity capture step is crucial to prevent purification from being the bottleneck in the manufacturing process. Despite its high cost and other disadvantages, Protein A chromatography still remains the optimal choice for antibody capture due to the excellent selectivity provided by this step. A dual flow loading strategy was used in conjunction with a new generation high capacity Protein A resin to maximize binding capacity without significantly increasing processing time. Optimum conditions were established using a simple empirical Design of Experiment (DOE) based model and verified with a wide panel of antibodies. Dynamic binding capacities of >65 g/L could be achieved under these new conditions, significantly higher by more than one and half times the values that have been typically achieved with Protein A in the past. Furthermore, comparable process performance and product quality was demonstrated for the Protein A step at the increased loading. © 2014 American Institute of Chemical Engineers.

  10. Maximizing Target Language Use in a Pre-­Service Practicum: Tensions, Power, and Identity Formation

    Science.gov (United States)

    Parks, Susan

    2015-01-01

    This study draws from a cultural-historical perspective to explore the experiences of two pre-­service ESL teachers in terms of their efforts to maximize the use of the target language during a school practicum. Both student teachers were fluent in English, had received training in maximizing target language use during their university studies,…

  11. Effects of feedback and educational Training on Maximization in choice Tasks: Experimental-game Evidence

    NARCIS (Netherlands)

    Antonides, G.; Maital, S.

    2002-01-01

    Compelling evidence exists that behavior is inconsistent with the assumptions of expected-utility maximization. However, if learning occurs, then maximization may take place asymptotically (albeit slowly). But a series of experiments by Herrnstein and his associates show that under very general

  12. An ethical justification of profit maximization

    DEFF Research Database (Denmark)

    Koch, Carsten Allan

    2010-01-01

    In much of the literature on business ethics and corporate social responsibility, it is more or less taken for granted that attempts to maximize profits are inherently unethical. The purpose of this paper is to investigate whether an ethical argument can be given in support of profit maximizing...... behaviour. It is argued that some form of consequential ethics must be applied, and that both profit seeking and profit maximization can be defended from a rule-consequential point of view. It is noted, however, that the result does not apply unconditionally, but requires that certain form of profit (and...

  13. Maximal supergravities and the E10 model

    International Nuclear Information System (INIS)

    Kleinschmidt, Axel; Nicolai, Hermann

    2006-01-01

    The maximal rank hyperbolic Kac-Moody algebra e 10 has been conjectured to play a prominent role in the unification of duality symmetries in string and M theory. We review some recent developments supporting this conjecture

  14. Maximizing Function through Intelligent Robot Actuator Control

    Data.gov (United States)

    National Aeronautics and Space Administration — Maximizing Function through Intelligent Robot Actuator Control Successful missions to Mars and beyond will only be possible with the support of high-performance...

  15. Independent Component Analysis by Entropy Maximization (INFOMAX)

    National Research Council Canada - National Science Library

    Garvey, Jennie H

    2007-01-01

    ... (BSS). The Infomax method separates unknown source signals from a number of signal mixtures by maximizing the entropy of a transformed set of signal mixtures and is accomplished by performing gradient ascent in MATLAB...

  16. Bipartite Bell Inequality and Maximal Violation

    International Nuclear Information System (INIS)

    Li Ming; Fei Shaoming; Li-Jost Xian-Qing

    2011-01-01

    We present new bell inequalities for arbitrary dimensional bipartite quantum systems. The maximal violation of the inequalities is computed. The Bell inequality is capable of detecting quantum entanglement of both pure and mixed quantum states more effectively. (general)

  17. A definition of maximal CP-violation

    International Nuclear Information System (INIS)

    Roos, M.

    1985-01-01

    The unitary matrix of quark flavour mixing is parametrized in a general way, permitting a mathematically natural definition of maximal CP violation. Present data turn out to violate this definition by 2-3 standard deviations. (orig.)

  18. Sequential roles of primary somatosensory cortex and posterior parietal cortex in tactile-visual cross-modal working memory: a single-pulse transcranial magnetic stimulation (spTMS) study.

    Science.gov (United States)

    Ku, Yixuan; Zhao, Di; Hao, Ning; Hu, Yi; Bodner, Mark; Zhou, Yong-Di

    2015-01-01

    Both monkey neurophysiological and human EEG studies have shown that association cortices, as well as primary sensory cortical areas, play an essential role in sequential neural processes underlying cross-modal working memory. The present study aims to further examine causal and sequential roles of the primary sensory cortex and association cortex in cross-modal working memory. Individual MRI-based single-pulse transcranial magnetic stimulation (spTMS) was applied to bilateral primary somatosensory cortices (SI) and the contralateral posterior parietal cortex (PPC), while participants were performing a tactile-visual cross-modal delayed matching-to-sample task. Time points of spTMS were 300 ms, 600 ms, 900 ms after the onset of the tactile sample stimulus in the task. The accuracy of task performance and reaction time were significantly impaired when spTMS was applied to the contralateral SI at 300 ms. Significant impairment on performance accuracy was also observed when the contralateral PPC was stimulated at 600 ms. SI and PPC play sequential and distinct roles in neural processes of cross-modal associations and working memory. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. Nuclear magnetic resonance experiments with dc SQUID amplifiers

    International Nuclear Information System (INIS)

    Heaney, M.B.

    1990-11-01

    The development and fabrication of dc SQUIDs (Superconducting QUantum Interference Devices) with Nb/Al 2 O 3 /Nb Josephson junctions is described. A theory of the dc SQUID as a radio-frequency amplifier is presented, with an optimization strategy that accounts for the loading and noise contributions of the postamplifier and maximizes the signal-to-noise ratio of the total system. The high sensitivity of the dc SQUID is extended to high field NMR. A dc SQUID is used as a tuned radio-frequency amplifier to detect pulsed nuclear magnetic resonance at 32 MHz from a metal film in a 3.5 Tesla static field. A total system noise temperature of 11 K has been achieved, at a bath temperature of 4.2 K. The minimum number of nuclear Bohr magnetons observable from a free precession signal after a single pulse is about 2 x 10 17 in a bandwidth of 25 kHz. In a separate experiment, a dc SQUID is used as a rf amplifier in a NQR experiment to observe a new resonance response mechanism. The net electric polarization of a NaClO 3 crystal due to the precessing electric quadrupole moments of the Cl nuclei is detected at 30 MHz. The sensitivity of NMR and NQR spectrometers using dc SQUID amplifiers is compared to the sensitivity of spectrometers using conventional rf amplifiers. A SQUID-based spectrometer has a voltage sensitivity which is comparable to the best achieved by a FET-based spectrometer, at these temperatures and operating frequencies

  20. Leveraging Twitter to Maximize the Radiology Meeting Experience.

    Science.gov (United States)

    Kalia, Vivek; Ortiz, Daniel A; Patel, Amy K; Moriarity, Andrew K; Canon, Cheri L; Duszak, Richard

    2018-01-01

    Over recent years, social media engagement has proliferated among physicians, health care systems, scientific journals, professional societies, and patients. In radiology, Twitter (Twitter Inc, San Francisco, California) has rapidly become the preferred social media engagement tool and is now an essential activity at many large radiology society meetings. Twitter offers a versatile, albeit simple, platform for anyone interested in engaging with others, regardless of title, stature, or geography. In radiology and other medical specialties, year-after-year increases in Twitter engagement before, during, and after professional society meetings continue with widespread positive feedback. This short-form messaging tool also allows users to connect and interact with high-impact individuals and organizations on an ongoing basis (rather than once a year during large meetings). Through live-polling, Twitter also has the power to gather global opinions on issues highly relevant to radiology's future, such as the Medicare Access and CHIP Reauthorization Act of 2015 (MACRA) or breast cancer screening. Also increasingly popular is "live-tweeting" of curated meeting content, which makes information from the meeting accessible to a global audience. Despite the promise of growing professional networks and enabling discussions that cross geographic boundaries, the risks of Twitter use during radiology meetings must be recognized and mitigated. These include posting of unpublished data without consent (eg, slide content captured on camera phones), propagation of misinformation, and copyright infringement. Despite these issues and with an eye towards professionalism, Twitter can nonetheless be used effectively to increase engagement among radiologists, radiology societies, and patients. Copyright © 2017 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  1. Configuring The REU Experience To Maximize Student Collaboration

    Science.gov (United States)

    Majkowski, L.; Pullin, M. J.

    2012-12-01

    The New Mexico Tech NSF-funded REU Program, Interdisciplinary Science for the Environment (ISE), hosted six cohorts of students between 2005 and 2010. The program ran for eight weeks during the first cycle and nine weeks during the second cycle, bringing in an average of twelve student participants per year. Students were provided with a stipend, food allowance, travel from home to New Mexico Tech, and free campus housing. The program sponsored weekend group field trips to scientific, environmental, and cultural sites of significance in New Mexico. For the second cycle, the ISE shared some programmatic elements with the New Mexico EPSCoR Undergraduate Research Opportunities Program (UROP). The majority of the research projects focused on the geosciences, with interdepartmental participation from researchers in earth science, hydrology, chemistry, environmental science, and biology. The ISE adopted a non-traditional approach to matching student participants with research projects and faculty mentors. Students were selected from different disciplines to work together in pairs on each project. This model provided the students with a peer collaborator in addition to the guidance of their faculty mentors and support from graduate students associated with the different projects. The focus on cohort, both within the individual research projects and each year's group, enabled and enhanced the students' critical thinking, problem-solving and teamwork skills. Students would routinely seek out the advice of their peers when they hit a roadblock in their research. This collaboration also occurred across the boundaries of the ISE and UROP cohorts. Long-term follow up has shown that a significant number of the student participants have continued on to graduate school. Students credit the program with developing their capacity to work on complex problems in an interdisciplinary group environment. Additionally, many students have continued contact with their research partners, faculty mentors and other members of their REU cohort.

  2. Resources and energetics determined dinosaur maximal size.

    Science.gov (United States)

    McNab, Brian K

    2009-07-21

    Some dinosaurs reached masses that were approximately 8 times those of the largest, ecologically equivalent terrestrial mammals. The factors most responsible for setting the maximal body size of vertebrates are resource quality and quantity, as modified by the mobility of the consumer, and the vertebrate's rate of energy expenditure. If the food intake of the largest herbivorous mammals defines the maximal rate at which plant resources can be consumed in terrestrial environments and if that limit applied to dinosaurs, then the large size of sauropods occurred because they expended energy in the field at rates extrapolated from those of varanid lizards, which are approximately 22% of the rates in mammals and 3.6 times the rates of other lizards of equal size. Of 2 species having the same energy income, the species that uses the most energy for mass-independent maintenance of necessity has a smaller size. The larger mass found in some marine mammals reflects a greater resource abundance in marine environments. The presumptively low energy expenditures of dinosaurs potentially permitted Mesozoic communities to support dinosaur biomasses that were up to 5 times those found in mammalian herbivores in Africa today. The maximal size of predatory theropods was approximately 8 tons, which if it reflected the maximal capacity to consume vertebrates in terrestrial environments, corresponds in predatory mammals to a maximal mass less than a ton, which is what is observed. Some coelurosaurs may have evolved endothermy in association with the evolution of feathered insulation and a small mass.

  3. Twitch interpolation technique in testing of maximal muscle strength

    DEFF Research Database (Denmark)

    Bülow, P M; Nørregaard, J; Danneskiold-Samsøe, B

    1993-01-01

    The aim was to study the methodological aspects of the muscle twitch interpolation technique in estimating the maximal force of contraction in the quadriceps muscle utilizing commercial muscle testing equipment. Six healthy subjects participated in seven sets of experiments testing the effects...... on twitch size of potentiation, time lag after potentiation, magnitude of voluntary force, stimulus amplitude, stimulus duration, angle of the knee, and angle of the hip. In addition, the consequences of submaximal potentiation on the estimation of maximal force from twitch sizes were studied in five...... healthy subjects. We found an increase in twitch size with increasing levels of potentiation and twitch size decreased exponentially following potentiation. We found a curvilinear relationship between twitch size and voluntary force, and these properties were more obvious when the stimulation intensity...

  4. An information maximization model of eye movements

    Science.gov (United States)

    Renninger, Laura Walker; Coughlan, James; Verghese, Preeti; Malik, Jitendra

    2005-01-01

    We propose a sequential information maximization model as a general strategy for programming eye movements. The model reconstructs high-resolution visual information from a sequence of fixations, taking into account the fall-off in resolution from the fovea to the periphery. From this framework we get a simple rule for predicting fixation sequences: after each fixation, fixate next at the location that minimizes uncertainty (maximizes information) about the stimulus. By comparing our model performance to human eye movement data and to predictions from a saliency and random model, we demonstrate that our model is best at predicting fixation locations. Modeling additional biological constraints will improve the prediction of fixation sequences. Our results suggest that information maximization is a useful principle for programming eye movements.

  5. Singularity Structure of Maximally Supersymmetric Scattering Amplitudes

    DEFF Research Database (Denmark)

    Arkani-Hamed, Nima; Bourjaily, Jacob L.; Cachazo, Freddy

    2014-01-01

    We present evidence that loop amplitudes in maximally supersymmetric (N=4) Yang-Mills theory (SYM) beyond the planar limit share some of the remarkable structures of the planar theory. In particular, we show that through two loops, the four-particle amplitude in full N=4 SYM has only logarithmic ...... singularities and is free of any poles at infinity—properties closely related to uniform transcendentality and the UV finiteness of the theory. We also briefly comment on implications for maximal (N=8) supergravity theory (SUGRA)....

  6. Finding Maximal Pairs with Bounded Gap

    DEFF Research Database (Denmark)

    Brodal, Gerth Stølting; Lyngsø, Rune B.; Pedersen, Christian N. S.

    1999-01-01

    . In this paper we present methods for finding all maximal pairs under various constraints on the gap. In a string of length n we can find all maximal pairs with gap in an upper and lower bounded interval in time O(n log n+z) where z is the number of reported pairs. If the upper bound is removed the time reduces...... to O(n+z). Since a tandem repeat is a pair where the gap is zero, our methods can be seen as a generalization of finding tandem repeats. The running time of our methods equals the running time of well known methods for finding tandem repeats....

  7. Maximizing band gaps in plate structures

    DEFF Research Database (Denmark)

    Halkjær, Søren; Sigmund, Ole; Jensen, Jakob Søndergaard

    2006-01-01

    Band gaps, i.e., frequency ranges in which waves cannot propagate, can be found in elastic structures for which there is a certain periodic modulation of the material properties or structure. In this paper, we maximize the band gap size for bending waves in a Mindlin plate. We analyze an infinite...

  8. Robust Utility Maximization Under Convex Portfolio Constraints

    International Nuclear Information System (INIS)

    Matoussi, Anis; Mezghani, Hanen; Mnif, Mohamed

    2015-01-01

    We study a robust maximization problem from terminal wealth and consumption under a convex constraints on the portfolio. We state the existence and the uniqueness of the consumption–investment strategy by studying the associated quadratic backward stochastic differential equation. We characterize the optimal control by using the duality method and deriving a dynamic maximum principle

  9. Robust Utility Maximization Under Convex Portfolio Constraints

    Energy Technology Data Exchange (ETDEWEB)

    Matoussi, Anis, E-mail: anis.matoussi@univ-lemans.fr [Université du Maine, Risk and Insurance institut of Le Mans Laboratoire Manceau de Mathématiques (France); Mezghani, Hanen, E-mail: hanen.mezghani@lamsin.rnu.tn; Mnif, Mohamed, E-mail: mohamed.mnif@enit.rnu.tn [University of Tunis El Manar, Laboratoire de Modélisation Mathématique et Numérique dans les Sciences de l’Ingénieur, ENIT (Tunisia)

    2015-04-15

    We study a robust maximization problem from terminal wealth and consumption under a convex constraints on the portfolio. We state the existence and the uniqueness of the consumption–investment strategy by studying the associated quadratic backward stochastic differential equation. We characterize the optimal control by using the duality method and deriving a dynamic maximum principle.

  10. Maximizing Resource Utilization in Video Streaming Systems

    Science.gov (United States)

    Alsmirat, Mohammad Abdullah

    2013-01-01

    Video streaming has recently grown dramatically in popularity over the Internet, Cable TV, and wire-less networks. Because of the resource demanding nature of video streaming applications, maximizing resource utilization in any video streaming system is a key factor to increase the scalability and decrease the cost of the system. Resources to…

  11. Maximizing scientific knowledge from randomized clinical trials

    DEFF Research Database (Denmark)

    Gustafsson, Finn; Atar, Dan; Pitt, Bertram

    2010-01-01

    Trialists have an ethical and financial responsibility to plan and conduct clinical trials in a manner that will maximize the scientific knowledge gained from the trial. However, the amount of scientific information generated by randomized clinical trials in cardiovascular medicine is highly...

  12. Maximizing Learning Potential in the Communicative Classroom.

    Science.gov (United States)

    Kumaravadivelu, B.

    1993-01-01

    A classroom observational study is presented to assess whether a macrostrategies framework will help communicative language teaching teachers to maximize learner potential in the classroom. Analysis of two classroom episodes revealed that one episode was evidently more communicative than the other. (seven references) (VWL)

  13. Faculty Salaries and the Maximization of Prestige

    Science.gov (United States)

    Melguizo, Tatiana; Strober, Myra H.

    2007-01-01

    Through the lens of the emerging economic theory of higher education, we look at the relationship between salary and prestige. Starting from the premise that academic institutions seek to maximize prestige, we hypothesize that monetary rewards are higher for faculty activities that confer prestige. We use data from the 1999 National Study of…

  14. A Model of College Tuition Maximization

    Science.gov (United States)

    Bosshardt, Donald I.; Lichtenstein, Larry; Zaporowski, Mark P.

    2009-01-01

    This paper develops a series of models for optimal tuition pricing for private colleges and universities. The university is assumed to be a profit maximizing, price discriminating monopolist. The enrollment decision of student's is stochastic in nature. The university offers an effective tuition rate, comprised of stipulated tuition less financial…

  15. Maximal Inequalities for Dependent Random Variables

    DEFF Research Database (Denmark)

    Hoffmann-Jorgensen, Jorgen

    2016-01-01

    Maximal inequalities play a crucial role in many probabilistic limit theorem; for instance, the law of large numbers, the law of the iterated logarithm, the martingale limit theorem and the central limit theorem. Let X-1, X-2,... be random variables with partial sums S-k = X-1 + ... + X...

  16. Coverage maximization under resource constraints using ...

    Indian Academy of Sciences (India)

    2015-02-07

    Feb 7, 2015 ... Dissemination of information has been one of the prime needs in almost every kind of communication network. The existing algorithms for this service, try to maximize the coverage, i.e., the number of distinct nodes to which a given piece of information could be conveyed under the constraints of time and ...

  17. Developing maximal neuromuscular power: Part 1--biological basis of maximal power production.

    Science.gov (United States)

    Cormie, Prue; McGuigan, Michael R; Newton, Robert U

    2011-01-01

    This series of reviews focuses on the most important neuromuscular function in many sport performances, the ability to generate maximal muscular power. Part 1 focuses on the factors that affect maximal power production, while part 2, which will follow in a forthcoming edition of Sports Medicine, explores the practical application of these findings by reviewing the scientific literature relevant to the development of training programmes that most effectively enhance maximal power production. The ability of the neuromuscular system to generate maximal power is affected by a range of interrelated factors. Maximal muscular power is defined and limited by the force-velocity relationship and affected by the length-tension relationship. The ability to generate maximal power is influenced by the type of muscle action involved and, in particular, the time available to develop force, storage and utilization of elastic energy, interactions of contractile and elastic elements, potentiation of contractile and elastic filaments as well as stretch reflexes. Furthermore, maximal power production is influenced by morphological factors including fibre type contribution to whole muscle area, muscle architectural features and tendon properties as well as neural factors including motor unit recruitment, firing frequency, synchronization and inter-muscular coordination. In addition, acute changes in the muscle environment (i.e. alterations resulting from fatigue, changes in hormone milieu and muscle temperature) impact the ability to generate maximal power. Resistance training has been shown to impact each of these neuromuscular factors in quite specific ways. Therefore, an understanding of the biological basis of maximal power production is essential for developing training programmes that effectively enhance maximal power production in the human.

  18. [Chemical constituents of Trichosanthes kirilowii Maxim].

    Science.gov (United States)

    Sun, Xiao-Ye; Wu, Hong-Hua; Fu, Ai-Zhen; Zhang, Peng

    2012-07-01

    To study the chemical constituents of Trichosanthes kirilowii Maxim., chromatographic methods such as D101 macroporous resin, silica gel column chromatographic technology, Sephadex LH-20, octadecylsilyl (ODS) column chromatographic technique and preparative HPLC were used and nine compounds were isolated from a 95% (v/v) ethanol extract of the plant. By using spectroscopic techniques including 1H NMR, 13C NMR, 1H-1H COSY, HSQC and HMBC, these compounds were identified as 5-ethoxymethyl-1-carboxyl propyl-1H-pyrrole-2-carbaldehyde (1), 5-hydroxymethyl-2-furfural (2), chrysoeriol (3), 4'-hydroxyscutellarin (4), vanillic acid (5), alpha-spinasterol (6), beta-D-glucopyranosyl-a-spinasterol (7), stigmast-7-en-3beta-ol (8), and adenosine (9), separately. Among them, compound 1 is a new compound, and compounds 3, 4 and 5 are isolated from the genus Trichosanthes kirilowii Maxim. for the first time.

  19. Deterministic quantum annealing expectation-maximization algorithm

    Science.gov (United States)

    Miyahara, Hideyuki; Tsumura, Koji; Sughiyama, Yuki

    2017-11-01

    Maximum likelihood estimation (MLE) is one of the most important methods in machine learning, and the expectation-maximization (EM) algorithm is often used to obtain maximum likelihood estimates. However, EM heavily depends on initial configurations and fails to find the global optimum. On the other hand, in the field of physics, quantum annealing (QA) was proposed as a novel optimization approach. Motivated by QA, we propose a quantum annealing extension of EM, which we call the deterministic quantum annealing expectation-maximization (DQAEM) algorithm. We also discuss its advantage in terms of the path integral formulation. Furthermore, by employing numerical simulations, we illustrate how DQAEM works in MLE and show that DQAEM moderate the problem of local optima in EM.

  20. Loop Amplitude Diagrams in Manifest, Maximal Supergravity

    Science.gov (United States)

    Karlsson, Anna

    The issue of finiteness of maximal supergravity has been subject to research for quite some time. Here, we approach that question through an examination of how to describe amplitude diagrams in D = 11 maximal supergravity from a field theory point of view. The strength of the formulation is the presence of manifest supersymmetry through the use of pure spinors. An initial analysis of what the subsequent characteristics turn out to be, partly in lower dimensions through dimensional reduction, gives at hand results that agree with previous work, pointing towards a first divergence for the 7-loop contribution to the 4-point amplitude in four dimensions. The text is mainly based on and may be regarded as an introduction to the main points presented there.

  1. Maximal frustration as an immunological principle.

    Science.gov (United States)

    de Abreu, F Vistulo; Mostardinha, P

    2009-03-06

    A fundamental problem in immunology is that of understanding how the immune system selects promptly which cells to kill without harming the body. This problem poses an apparent paradox. Strong reactivity against pathogens seems incompatible with perfect tolerance towards self. We propose a different view on cellular reactivity to overcome this paradox: effector functions should be seen as the outcome of cellular decisions which can be in conflict with other cells' decisions. We argue that if cellular systems are frustrated, then extensive cross-reactivity among the elements in the system can decrease the reactivity of the system as a whole and induce perfect tolerance. Using numerical and mathematical analyses, we discuss two simple models that perform optimal pathogenic detection with no autoimmunity if cells are maximally frustrated. This study strongly suggests that a principle of maximal frustration could be used to build artificial immune systems. It would be interesting to test this principle in the real adaptive immune system.

  2. Dynamical supersymmetry in maximally supersymmetric gauge theories

    Science.gov (United States)

    Belyaev, Dmitry V.

    2010-06-01

    Maximally supersymmetric theories can be described by a single scalar superfield in light-cone superspace. When they are also (super)conformally invariant, they are uniquely specified by the form of the dynamical supersymmetry. We present an explicit derivation of the light-cone superspace form of the dynamical supersymmetry in the cases of ten- and four-dimensional super-Yang-Mills, and the three-dimensional Bagger-Lambert-Gustavsson theory, starting from the covariant formulation of these theories.

  3. Definable maximal discrete sets in forcing extensions

    DEFF Research Database (Denmark)

    Törnquist, Asger Dag; Schrittesser, David

    2018-01-01

    Let  be a Σ11 binary relation, and recall that a set A is -discrete if no two elements of A are related by . We show that in the Sacks and Miller forcing extensions of L there is a Δ12 maximal -discrete set. We use this to answer in the negative the main question posed in [5] by showing...

  4. Increasing Efficiency by Maximizing Electrical Output

    Science.gov (United States)

    2016-07-27

    turbines whose efficiency decreases with system size driving up costs . The cost in $/W for our system is substantially less than other competitive...basis. That forecast of a $100,000 sales price is based on a detailed analysis of anticipated bill of materials costs when manufacturing and...27-07-2016 Cost and Performance Report 04/01/2012 - 07/01/2016 Increasing Efficiency by Maximizing Electrical Output Ted Eveleth, COO, Ener-G-Rotors

  5. Cardiorespiratory Coordination in Repeated Maximal Exercise

    Directory of Open Access Journals (Sweden)

    Sergi Garcia-Retortillo

    2017-06-01

    Full Text Available Increases in cardiorespiratory coordination (CRC after training with no differences in performance and physiological variables have recently been reported using a principal component analysis approach. However, no research has yet evaluated the short-term effects of exercise on CRC. The aim of this study was to delineate the behavior of CRC under different physiological initial conditions produced by repeated maximal exercises. Fifteen participants performed 2 consecutive graded and maximal cycling tests. Test 1 was performed without any previous exercise, and Test 2 6 min after Test 1. Both tests started at 0 W and the workload was increased by 25 W/min in males and 20 W/min in females, until they were not able to maintain the prescribed cycling frequency of 70 rpm for more than 5 consecutive seconds. A principal component (PC analysis of selected cardiovascular and cardiorespiratory variables (expired fraction of O2, expired fraction of CO2, ventilation, systolic blood pressure, diastolic blood pressure, and heart rate was performed to evaluate the CRC defined by the number of PCs in both tests. In order to quantify the degree of coordination, the information entropy was calculated and the eigenvalues of the first PC (PC1 were compared between tests. Although no significant differences were found between the tests with respect to the performed maximal workload (Wmax, maximal oxygen consumption (VO2 max, or ventilatory threshold (VT, an increase in the number of PCs and/or a decrease of eigenvalues of PC1 (t = 2.95; p = 0.01; d = 1.08 was found in Test 2 compared to Test 1. Moreover, entropy was significantly higher (Z = 2.33; p = 0.02; d = 1.43 in the last test. In conclusion, despite the fact that no significant differences were observed in the conventionally explored maximal performance and physiological variables (Wmax, VO2 max, and VT between tests, a reduction of CRC was observed in Test 2. These results emphasize the interest of CRC

  6. Violation of Conversational Maxims in the Avengers Movie

    OpenAIRE

    Sri Juriati Ownie, David Hamonangan Sihite and

    2015-01-01

    The study deals with the types of maxims violation in The Avengers movie'sscript. The objectives of the study were to discover the types of maxims violation,the most dominant maxim violation, and to explain the implication of the mostdominant maxim violation in The Avengers movie. The source of the data was theconversations in The Avengers movie. The data was the script of The Avengersmovie. There were 55 maxim violations in this research. The descriptivequalitative design was used to analyze...

  7. Preliminary accelerator plans for maximizing the integrated LHC luminosity

    CERN Document Server

    Benedikt, Michael; Ruggiero, F; Ostojic, R; Scandale, Walter; Shaposhnikova, Elena; Wenninger, J

    2006-01-01

    A working group on "Proton Accelerators for the Future" (PAF) has been created in May 2005 by the CERN direction to elaborate a baseline scenario of the possible development and upgrade of the present Proton Accelerator Complex. This report is the result of the investigation conducted until the end of 2005, in close connection with the working group on "Physics Opportunities with Future Proton Accelerators" (POFPA) and is consistent with their recommendations. Focused on the goal of maximizing the integrated luminosity for the LHC experiments, a scenario of evolution is proposed, subject to further refinement using the future experience of commissioning and running-in the collider and its injector complex. The actions to be taken in terms of consolidation, R & D and improvement are outlined. The benefits for other types of physics are mentioned and will be investigated in more detail in the future.

  8. Changes of maximal muscle torque and maximal power output of lower extremities in male judoists during training

    OpenAIRE

    Buśko, Krzysztof; Nowak, Anna

    2008-01-01

    Purpose. The aim of the study was to follow changes of the maximal muscle torque and maximal power output of lower extremities in male judoists during pre-competition training (PCT). The original hypothesis assumed that different training loads would cause changes of the maximal muscle torque and maximal power output of legs in male judoists during pre-competition training, but not changes of the topography of the maximal muscle torque in all muscle groups. Basic procedures. The study sample ...

  9. Gain maximization in a probabilistic entanglement protocol

    Science.gov (United States)

    di Lorenzo, Antonio; Esteves de Queiroz, Johnny Hebert

    Entanglement is a resource. We can therefore define gain as a monotonic function of entanglement G (E) . If a pair with entanglement E is produced with probability P, the net gain is N = PG (E) - (1 - P) C , where C is the cost of a failed attempt. We study a protocol where a pair of quantum systems is produced in a maximally entangled state ρm with probability Pm, while it is produced in a partially entangled state ρp with the complementary probability 1 -Pm . We mix a fraction w of the partially entangled pairs with the maximally entangled ones, i.e. we take the state to be ρ = (ρm + wUlocρpUloc+) / (1 + w) , where Uloc is an appropriate unitary local operation designed to maximize the entanglement of ρ. This procedure on one hand reduces the entanglement E, and hence the gain, but on the other hand it increases the probability of success to P =Pm + w (1 -Pm) , therefore the net gain N may increase. There may be hence, a priori, an optimal value for w, the fraction of failed attempts that we mix in. We show that, in the hypothesis of a linear gain G (E) = E , even assuming a vanishing cost C -> 0 , the net gain N is increasing with w, therefore the best strategy is to always mix the partially entangled states. Work supported by CNPq, Conselho Nacional de Desenvolvimento Científico e Tecnológico, proc. 311288/2014-6, and by FAPEMIG, Fundação de Amparo à Pesquisa de Minas Gerais, proc. IC-FAPEMIG2016-0269 and PPM-00607-16.

  10. Using molecular biology to maximize concurrent training.

    Science.gov (United States)

    Baar, Keith

    2014-11-01

    Very few sports use only endurance or strength. Outside of running long distances on a flat surface and power-lifting, practically all sports require some combination of endurance and strength. Endurance and strength can be developed simultaneously to some degree. However, the development of a high level of endurance seems to prohibit the development or maintenance of muscle mass and strength. This interaction between endurance and strength is called the concurrent training effect. This review specifically defines the concurrent training effect, discusses the potential molecular mechanisms underlying this effect, and proposes strategies to maximize strength and endurance in the high-level athlete.

  11. What currency do bumble bees maximize?

    Directory of Open Access Journals (Sweden)

    Nicholas L Charlton

    2010-08-01

    Full Text Available In modelling bumble bee foraging, net rate of energetic intake has been suggested as the appropriate currency. The foraging behaviour of honey bees is better predicted by using efficiency, the ratio of energetic gain to expenditure, as the currency. We re-analyse several studies of bumble bee foraging and show that efficiency is as good a currency as net rate in terms of predicting behaviour. We suggest that future studies of the foraging of bumble bees should be designed to distinguish between net rate and efficiency maximizing behaviour in an attempt to discover which is the more appropriate currency.

  12. Maximally entangled mixed states and conditional entropies

    International Nuclear Information System (INIS)

    Batle, J.; Casas, M.; Plastino, A.; Plastino, A.R.

    2005-01-01

    The maximally entangled mixed states of Munro et al. [Phys. Rev. A 64, 030302 (2001)] are shown to exhibit interesting features vis a vis conditional entropic measures. The same happens with the Ishizaka and Hiroshima states [Phys. Rev. A 62, 022310 (2000)], whose entanglement degree cannot be increased by acting on them with logic gates. Special types of entangled states that do not violate classical entropic inequalities are seen to exist in the space of two qubits. Special meaning can be assigned to the Munro et al. special participation ratio of 1.8

  13. Maximizing policy learning in international committees

    DEFF Research Database (Denmark)

    Nedergaard, Peter

    2007-01-01

    , this article demonstrates that valuable lessons can be learned about policy learning, in practice and theoretically, by analysing the cooperation in the OMC committees. Using the Advocacy Coalition Framework as the starting point of analysis, 15 hypotheses on policy learning are tested. Among other things......, it is concluded that in order to maximize policy learning in international committees, empirical data should be made available to committees and provided by sources close to the participants (i.e. the Commission). In addition, the work in the committees should be made prestigious in order to attract well...

  14. Techniques and technologies to maximize mucosal exposure.

    Science.gov (United States)

    Moons, Leon M G; Gralnek, Ian M; Siersema, Peter D

    2015-04-01

    Performing high-quality colonoscopy is one of the important goals of gastroenterology practices and requires achieving a high level of bowel cleansing, performing good and safe polypectomy, and detecting all polyps present in the colon. This article summarizes currently available techniques and technologies to maximize mucosal visualization. Several maneuvers can be applied during insertion and withdrawal of the colonoscope to optimize mucosal visualization and decrease the number of missed polyps. Newly developed technologies support the endoscopist in the detection of polyps. Each technique is reviewed, with emphasis on the impact on colorectal polyp detection. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. Maximizing versus satisficing: happiness is a matter of choice.

    Science.gov (United States)

    Schwartz, Barry; Ward, Andrew; Monterosso, John; Lyubomirsky, Sonja; White, Katherine; Lehman, Darrin R

    2002-11-01

    Can people feel worse off as the options they face increase? The present studies suggest that some people--maximizers--can. Study 1 reported a Maximization Scale, which measures individual differences in desire to maximize. Seven samples revealed negative correlations between maximization and happiness, optimism, self-esteem, and life satisfaction, and positive correlations between maximization and depression, perfectionism, and regret. Study 2 found maximizers less satisfied than nonmaximizers (satisficers) with consumer decisions, and more likely to engage in social comparison. Study 3 found maximizers more adversely affected by upward social comparison. Study 4 found maximizers more sensitive to regret and less satisfied in an ultimatum bargaining game. The interaction between maximizing and choice is discussed in terms of regret, adaptation, and self-blame.

  16. Developing maximal neuromuscular power: part 2 - training considerations for improving maximal power production.

    Science.gov (United States)

    Cormie, Prue; McGuigan, Michael R; Newton, Robert U

    2011-02-01

    This series of reviews focuses on the most important neuromuscular function in many sport performances: the ability to generate maximal muscular power. Part 1, published in an earlier issue of Sports Medicine, focused on the factors that affect maximal power production while part 2 explores the practical application of these findings by reviewing the scientific literature relevant to the development of training programmes that most effectively enhance maximal power production. The ability to generate maximal power during complex motor skills is of paramount importance to successful athletic performance across many sports. A crucial issue faced by scientists and coaches is the development of effective and efficient training programmes that improve maximal power production in dynamic, multi-joint movements. Such training is referred to as 'power training' for the purposes of this review. Although further research is required in order to gain a deeper understanding of the optimal training techniques for maximizing power in complex, sports-specific movements and the precise mechanisms underlying adaptation, several key conclusions can be drawn from this review. First, a fundamental relationship exists between strength and power, which dictates that an individual cannot possess a high level of power without first being relatively strong. Thus, enhancing and maintaining maximal strength is essential when considering the long-term development of power. Second, consideration of movement pattern, load and velocity specificity is essential when designing power training programmes. Ballistic, plyometric and weightlifting exercises can be used effectively as primary exercises within a power training programme that enhances maximal power. The loads applied to these exercises will depend on the specific requirements of each particular sport and the type of movement being trained. The use of ballistic exercises with loads ranging from 0% to 50% of one-repetition maximum (1RM) and

  17. Maximal liquid bridges between horizontal cylinders

    Science.gov (United States)

    Huppert, Herbert E.; Neufeld, Jerome A.

    2016-01-01

    We investigate two-dimensional liquid bridges trapped between pairs of identical horizontal cylinders. The cylinders support forces owing to surface tension and hydrostatic pressure that balance the weight of the liquid. The shape of the liquid bridge is determined by analytically solving the nonlinear Laplace–Young equation. Parameters that maximize the trapping capacity (defined as the cross-sectional area of the liquid bridge) are then determined. The results show that these parameters can be approximated with simple relationships when the radius of the cylinders is small compared with the capillary length. For such small cylinders, liquid bridges with the largest cross-sectional area occur when the centre-to-centre distance between the cylinders is approximately twice the capillary length. The maximum trapping capacity for a pair of cylinders at a given separation is linearly related to the separation when it is small compared with the capillary length. The meniscus slope angle of the largest liquid bridge produced in this regime is also a linear function of the separation. We additionally derive approximate solutions for the profile of a liquid bridge, using the linearized Laplace–Young equation. These solutions analytically verify the above-mentioned relationships obtained for the maximization of the trapping capacity. PMID:27616922

  18. Maximization techniques for oilfield development profits

    International Nuclear Information System (INIS)

    Lerche, I.

    1999-01-01

    In 1981 Nind provided a quantitative procedure for estimating the optimum number of development wells to emplace on an oilfield to maximize profit. Nind's treatment assumed that there was a steady selling price, that all wells were placed in production simultaneously, and that each well's production profile was identical and a simple exponential decline with time. This paper lifts these restrictions to allow for price fluctuations, variable with time emplacement of wells, and production rates that are more in line with actual production records than is a simple exponential decline curve. As a consequence, it is possible to design production rate strategies, correlated with price fluctuations, so as to maximize the present-day worth of a field. For price fluctuations that occur on a time-scale rapid compared to inflation rates it is appropriate to have production rates correlate directly with such price fluctuations. The same strategy does not apply for price fluctuations occurring on a time-scale long compared to inflation rates where, for small amplitudes in the price fluctuations, it is best to sell as much product as early as possible to overcome inflation factors, while for large amplitude fluctuations the best strategy is to sell product as early as possible but to do so mainly on price upswings. Examples are provided to show how these generalizations of Nind's (1981) formula change the complexion of oilfield development optimization. (author)

  19. Spiders Tune Glue Viscosity to Maximize Adhesion.

    Science.gov (United States)

    Amarpuri, Gaurav; Zhang, Ci; Diaz, Candido; Opell, Brent D; Blackledge, Todd A; Dhinojwala, Ali

    2015-11-24

    Adhesion in humid conditions is a fundamental challenge to both natural and synthetic adhesives. Yet, glue from most spider species becomes stickier as humidity increases. We find the adhesion of spider glue, from five diverse spider species, maximizes at very different humidities that matches their foraging habitats. By using high-speed imaging and spreading power law, we find that the glue viscosity varies over 5 orders of magnitude with humidity for each species, yet the viscosity at maximal adhesion for each species is nearly identical, 10(5)-10(6) cP. Many natural systems take advantage of viscosity to improve functional response, but spider glue's humidity responsiveness is a novel adaptation that makes the glue stickiest in each species' preferred habitat. This tuning is achieved by a combination of proteins and hygroscopic organic salts that determines water uptake in the glue. We therefore anticipate that manipulation of polymer-salts interaction to control viscosity can provide a simple mechanism to design humidity responsive smart adhesives.

  20. Energy conservation and maximal entropy production in enzyme reactions.

    Science.gov (United States)

    Dobovišek, Andrej; Vitas, Marko; Brumen, Milan; Fajmut, Aleš

    2017-08-01

    A procedure for maximization of the density of entropy production in a single stationary two-step enzyme reaction is developed. Under the constraints of mass conservation, fixed equilibrium constant of a reaction and fixed products of forward and backward enzyme rate constants the existence of maximum in the density of entropy production is demonstrated. In the state with maximal density of entropy production the optimal enzyme rate constants, the stationary concentrations of the substrate and the product, the stationary product yield as well as the stationary reaction flux are calculated. The test, whether these calculated values of the reaction parameters are consistent with their corresponding measured values, is performed for the enzyme Glucose Isomerase. It is found that calculated and measured rate constants agree within an order of magnitude, whereas the calculated reaction flux and the product yield differ from their corresponding measured values for less than 20 % and 5 %, respectively. This indicates that the enzyme Glucose Isomerase, considered in a non-equilibrium stationary state, as found in experiments using the continuous stirred tank reactors, possibly operates close to the state with the maximum in the density of entropy production. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Maximizing Photoluminescence Extraction in Silicon Photonic Crystal Slabs.

    Science.gov (United States)

    Mahdavi, Ali; Sarau, George; Xavier, Jolly; Paraïso, Taofiq K; Christiansen, Silke; Vollmer, Frank

    2016-04-26

    Photonic crystal modes can be tailored for increasing light matter interactions and light extraction efficiencies. These PhC properties have been explored for improving the device performance of LEDs, solar cells and precision biosensors. Tuning the extended band structure of 2D PhC provides a means for increasing light extraction throughout a planar device. This requires careful design and fabrication of PhC with a desirable mode structure overlapping with the spectral region of emission. We show a method for predicting and maximizing light extraction from 2D photonic crystal slabs, exemplified by maximizing silicon photoluminescence (PL). Systematically varying the lattice constant and filling factor, we predict the increases in PL intensity from band structure calculations and confirm predictions in micro-PL experiments. With the near optimal design parameters of PhC, we demonstrate more than 500-fold increase in PL intensity, measured near band edge of silicon at room temperature, an enhancement by an order of magnitude more than what has been reported.

  2. Maximal mydriasis evaluation in cataract surgery

    Directory of Open Access Journals (Sweden)

    Ho Tony

    1992-01-01

    Full Text Available We propose the Maximal Mydriasis Test (MMT as a simple and safe means to provide the cataract surgeon with objective and dependable pre-operative information on the idiosyncratic mydriatic response of the pupil. The MMT results of a consecutive series of 165 eyes from 100 adults referred for cataract evaluation are presented to illustrate its practical applications and value. The results of the MMT allows the surgeon to anticipate problem eyes pre-operatively so that he can plan his surgical strategy more appropriately and effectively. Conversely, the surgeon can also appropriately and confidently plan surgical procedures where wide pupillary dilation is important. The MMT has also helped improve our cost-effectiveness by cutting down unnecessary delays in the operating room and enabling better utilisation of restricted costly resources.

  3. MAXIMIZING THE BENEFITS OF ERP SYSTEMS

    Directory of Open Access Journals (Sweden)

    Paulo André da Conceição Menezes

    2010-04-01

    Full Text Available The ERP (Enterprise Resource Planning systems have been consolidated in companies with different sizes and sectors, allowing their real benefits to be definitively evaluated. In this study, several interactions have been studied in different phases, such as the strategic priorities and strategic planning defined as ERP Strategy; business processes review and the ERP selection in the pre-implementation phase, the project management and ERP adaptation in the implementation phase, as well as the ERP revision and integration efforts in the post-implementation phase. Through rigorous use of case study methodology, this research led to developing and to testing a framework for maximizing the benefits of the ERP systems, and seeks to contribute for the generation of ERP initiatives to optimize their performance.

  4. Distributed-Memory Fast Maximal Independent Set

    Energy Technology Data Exchange (ETDEWEB)

    Kanewala Appuhamilage, Thejaka Amila J.; Zalewski, Marcin J.; Lumsdaine, Andrew

    2017-09-13

    The Maximal Independent Set (MIS) graph problem arises in many applications such as computer vision, information theory, molecular biology, and process scheduling. The growing scale of MIS problems suggests the use of distributed-memory hardware as a cost-effective approach to providing necessary compute and memory resources. Luby proposed four randomized algorithms to solve the MIS problem. All those algorithms are designed focusing on shared-memory machines and are analyzed using the PRAM model. These algorithms do not have direct efficient distributed-memory implementations. In this paper, we extend two of Luby’s seminal MIS algorithms, “Luby(A)” and “Luby(B),” to distributed-memory execution, and we evaluate their performance. We compare our results with the “Filtered MIS” implementation in the Combinatorial BLAS library for two types of synthetic graph inputs.

  5. Maximizing policy learning in international committees

    DEFF Research Database (Denmark)

    Nedergaard, Peter

    2007-01-01

    , this article demonstrates that valuable lessons can be learned about policy learning, in practice and theoretically, by analysing the cooperation in the OMC committees. Using the Advocacy Coalition Framework as the starting point of analysis, 15 hypotheses on policy learning are tested. Among other things......In the voluminous literature on the European Union's open method of coordination (OMC), no one has hitherto analysed on the basis of scholarly examination the question of what contributes to the learning processes in the OMC committees. On the basis of a questionnaire sent to all participants......, it is concluded that in order to maximize policy learning in international committees, empirical data should be made available to committees and provided by sources close to the participants (i.e. the Commission). In addition, the work in the committees should be made prestigious in order to attract well...

  6. Primordial two-component maximally symmetric inflation

    Science.gov (United States)

    Enqvist, K.; Nanopoulos, D. V.; Quirós, M.; Kounnas, C.

    1985-12-01

    We propose a two-component inflation model, based on maximally symmetric supergravity, where the scales of reheating and the inflation potential at the origin are decoupled. This is possible because of the second-order phase transition from SU(5) to SU(3)×SU(2)×U(1) that takes place when φ≅φcinflation at the global minimum, and leads to a reheating temperature TR≅(1015-1016) GeV. This makes it possible to generate baryon asymmetry in the conventional way without any conflict with experimental data on proton lifetime. The mass of the gravitinos is m3/2≅1012 GeV, thus avoiding the gravitino problem. Monopoles are diluted by residual inflation in the broken phase below the cosmological bounds if φcUSA.

  7. Constrained information maximization by free energy minimization

    Science.gov (United States)

    Kamimura, Ryotaro

    2011-10-01

    In this paper we introduce free energy-based methods to constrain mutual information maximization, developed to realize competitive learning. The new method is introduced to simplify the computational procedures of mutual information and to improve the fidelity of representation and to stabilize learning. First, the free energy is effective in simplifying the computation procedures of mutual information because we need not directly compute mutual information, which needs heavy computation, but only deals with partition functions. With partition functions, computational complexity is significantly reduced. Second, fidelity to input patterns can be improved because training errors between input patterns and connection weights are implicitly incorporated. This means that mutual information is maximized under the constraint of the errors between input patterns and connection weights. Finally, learning can be stabilized in our approach. One of the problems of the free energy approach is that learning processes should be carefully controlled to keep its stability. The present paper shows that the conventional computational techniques in the field of self-organizing maps are really effective in controlling the processes. In particular, minimum information production learning can be used further to stabilize learning by decreasing information obtained at each learning step as much as possible. Thus, we can expect that our new method can be used to increase mutual information between competitive units and input patterns without decreasing errors between input patterns and connection weights and with stabilized learning processes. We applied the free energy-based models to the well-known Iris problem and a student survey, and succeeded in improving the performance in terms of classification rates. In addition, the minimum information production learning turned out to be effective in stabilizing learning.

  8. Maximal lattice free bodies, test sets and the Frobenius problem

    DEFF Research Database (Denmark)

    Jensen, Anders Nedergaard; Lauritzen, Niels; Roune, Bjarke Hammersholt

    Maximal lattice free bodies are maximal polytopes without interior integral points. Scarf initiated the study of maximal lattice free bodies relative to the facet normals in a fixed matrix. In this paper we give an efficient algorithm for computing the maximal lattice free bodies of an integral...... method is inspired by the novel algorithm by Einstein, Lichtblau, Strzebonski and Wagon and the Groebner basis approach by Roune....

  9. Maximal saddle solution of a nonlinear elliptic equation involving the ...

    Indian Academy of Sciences (India)

    Home; Journals; Proceedings – Mathematical Sciences; Volume 124; Issue 1. Maximal Saddle ... -Laplacian; maximal saddle solution; monotone iteration methods. ... We prove the existence of a maximal saddle solution of the nonlinear elliptic equation involving the -Laplacian, by using the method of monotone iteration,.

  10. Origin of constrained maximal CP violation in flavor symmetry

    Science.gov (United States)

    He, Hong-Jian; Rodejohann, Werner; Xu, Xun-Jie

    2015-12-01

    Current data from neutrino oscillation experiments are in good agreement with δ = -π/2 and θ23 =π/4 under the standard parametrization of the mixing matrix. We define the notion of ;constrained maximal CP violation; (CMCPV) for predicting these features and study their origin in flavor symmetry. We derive the parametrization-independent solution of CMCPV and give a set of equivalent definitions for it. We further present a theorem on how the CMCPV can be realized. This theorem takes the advantage of residual symmetries in neutrino and charged lepton mass matrices, and states that, up to a few minor exceptions, (| δ | ,θ23) = (π/2 ,π/4) is generated when those symmetries are real. The often considered μ- τ reflection symmetry, as well as specific discrete subgroups of O(3), is a special case of our theorem.

  11. Teaching for more effective learning: Seven maxims for practice

    International Nuclear Information System (INIS)

    McMahon, Tim

    2006-01-01

    Starting from the assumption that deep learning, which seeks lasting mastery over a subject, is more desirable in professional education than shallow learning, which is merely designed to pass academic assessments, this paper suggests ways in which teachers in higher education can encourage the former. Noting that students tend to adopt either a shallow or deep approach in response to their experiences in the classroom and their understanding of what the assessment regime requires, it argues that, as a consequence, it ought to be possible to prompt more students to adopt deep learning approaches by manipulating teaching and assessment strategies. The literature on teaching and learning is explored in order to derive maxims of good practice which, if followed, can reasonably be expected to promote deep learning and discourage surface learning. It is argued that this will lead to more effective preparation for the real world of professional practice

  12. Correntropy Maximization via ADMM: Application to Robust Hyperspectral Unmixing

    Science.gov (United States)

    Zhu, Fei; Halimi, Abderrahim; Honeine, Paul; Chen, Badong; Zheng, Nanning

    2017-09-01

    In hyperspectral images, some spectral bands suffer from low signal-to-noise ratio due to noisy acquisition and atmospheric effects, thus requiring robust techniques for the unmixing problem. This paper presents a robust supervised spectral unmixing approach for hyperspectral images. The robustness is achieved by writing the unmixing problem as the maximization of the correntropy criterion subject to the most commonly used constraints. Two unmixing problems are derived: the first problem considers the fully-constrained unmixing, with both the non-negativity and sum-to-one constraints, while the second one deals with the non-negativity and the sparsity-promoting of the abundances. The corresponding optimization problems are solved efficiently using an alternating direction method of multipliers (ADMM) approach. Experiments on synthetic and real hyperspectral images validate the performance of the proposed algorithms for different scenarios, demonstrating that the correntropy-based unmixing is robust to outlier bands.

  13. Maximal respiratory pressures among adolescent swimmers

    Directory of Open Access Journals (Sweden)

    M.A. Rocha Crispino Santos

    2011-03-01

    Full Text Available Maximal inspiratory pressures (MIP and maximal expiratory pressures (MEP are useful indices of respiratory muscle strength in athletes.The aims of this study were: to describe the strength of the respiratory muscles of Olympic junior swim team, at baseline and after a standard physical training; and to determine if there is a differential inspiratory and expiratory pressure response to the physical training.A cross-sectional study evaluated 28 international-level swimmers with ages ranging from 15 to 17 years, 19 (61% being males. At baseline, MIP was found to be lower in females (P = .001. The mean values reached by males and females were: MIP(cmH2O = M: 100.4 (± 26.5/F: 67.8 (± 23.2; MEP (cmH2O = M: 87.4 (± 20.7/F: 73.9 (± 17.3. After the physical training they reached: MIP (cmH2O = M: 95.3 (± 30.3/F: 71.8 (± 35.6; MEP (cmH2O = M: 82.8 (± 26.2/F: 70.4 (± 8.3.No differential pressure responses were observed in either males or females. These results suggest that swimmers can sustain the magnitude of the initial maximal pressures. Other studies should be developed to clarify if MIP and MEP could be used as a marker of an athlete's performance Sumário: Pressões inspiratórias máximas (PIM e pressões expiratórias máximas (PEM são indicadores úteis de força muscular em atletas.Os objetivos desse estudo foram: descrever a força da musculatura respiratória de uma equipe Olímpica júnior de natação, em repouso e após um exercício físico padronizado e. determinar o diferencial de pressão inspiratória e expiratória obtido como resposta ao exercício físico.Um estudo descritivo avaliou 28 nadadores de nível internacional, com idades variáveis entre 15 a 17 anos, sendo 19 (61% do sexo masculino. Em repouso, os valores mais baixos de PIM foram encontrados no sexo feminino (p = 0,001. Os valores m

  14. Witten spinors on maximal, conformally flat hypersurfaces

    International Nuclear Information System (INIS)

    Frauendiener, Joerg; Nester, James M; Szabados, Laszlo B

    2011-01-01

    The boundary conditions that exclude zeros of the solutions of the Witten equation (and hence guarantee the existence of a 3-frame satisfying the so-called special orthonormal frame gauge conditions) are investigated. We determine the general form of the conformally invariant boundary conditions for the Witten equation, and find the boundary conditions that characterize the constant and the conformally constant spinor fields among the solutions of the Witten equations on compact domains in extrinsically and intrinsically flat, and on maximal, intrinsically globally conformally flat spacelike hypersurfaces, respectively. We also provide a number of exact solutions of the Witten equation with various boundary conditions (both at infinity and on inner or outer boundaries) that single out nowhere vanishing spinor fields on the flat, non-extreme Reissner-Nordstroem and Brill-Lindquist data sets. Our examples show that there is an interplay between the boundary conditions, the global topology of the hypersurface and the existence/non-existence of zeros of the solutions of the Witten equation.

  15. New features of the maximal abelian projection

    International Nuclear Information System (INIS)

    Bornyakov, V.G.; Polikarpov, M.I.; Syritsyn, S.N.; Schierholz, G.; Suzuki, T.

    2005-12-01

    After fixing the Maximal Abelian gauge in SU(2) lattice gauge theory we decompose the nonabelian gauge field into the so called monopole field and the modified nonabelian field with monopoles removed. We then calculate respective static potentials and find that the potential due to the modified nonabelian field is nonconfining while, as is well known, the monopole field potential is linear. Furthermore, we show that the sum of these potentials approximates the nonabelian static potential with 5% or higher precision at all distances considered. We conclude that at large distances the monopole field potential describes the classical energy of the hadronic string while the modified nonabelian field potential describes the string fluctuations. Similar decomposition was observed to work for the adjoint static potential. A check was also made of the center projection in the direct center gauge. Two static potentials, determined by projected Z 2 and by modified nonabelian field without Z 2 component were calculated. It was found that their sum is a substantially worse approximation of the SU(2) static potential than that found in the monopole case. It is further demonstrated that similar decomposition can be made for the flux tube action/energy density. (orig.)

  16. New features of the maximal abelian projection

    International Nuclear Information System (INIS)

    Bornyakov, V.G.; Polikarpov, M.I.; Schierholz, G.; Suzuki, T.; Syritsyn, S.N.

    2006-01-01

    After fixing the Maximal Abelian gauge in SU(2) lattice gauge theory we decompose the nonabelian gauge field into the so called monopole field and the modified nonabelian field with monopoles removed. We then calculate respective static potentials and find that the potential due to the modified nonabelian field is nonconfining while, as is well known, the monopole field potential is linear. Furthermore, we show that the sum of these potentials approximates the nonabelian static potential with 5% or higher precision at all distances considered. We conclude that at large distances the monopole field potential describes the classical energy of the hadronic string while the modified nonabelian field potential describes the string fluctuations. Similar decomposition was observed to work for the adjoint static potential. A check was also made of the center projection in the direct center gauge. Two static potentials, determined by projected Z 2 and by modified nonabelian field without Z 2 component were calculated. It was found that their sum is a substantially worse approximation of the SU(2) static potential than that found in the monopole case. It is further demonstrated that similar decomposition can be made for the flux tube action/energy density

  17. Maximizing Exosome Colloidal Stability Following Electroporation

    Science.gov (United States)

    Hood, Joshua L.; Scott, Michael J.; Wickline, Samuel A.

    2014-01-01

    Development of exosome based semi-synthetic nanovesicles for diagnostic and therapeutic purposes requires novel approaches to load exosomes with cargo. Electroporation has previously been used to load exosomes with RNA. However, investigations into exosome colloidal stability following electroporation have not been considered. Herein, we report the development of a unique trehalose pulse media (TPM) that minimizes exosome aggregation following electroporation. Dynamic light scattering (DLS) and RNA absorbance were employed to determine the extent of exosome aggregation and electroextraction post electroporation in TPM compared to common PBS pulse media or sucrose pulse media (SPM). Use of TPM to disaggregate melanoma exosomes post electroporation was dependent on both exosome concentration and electric field strength. TPM maximized exosome dispersal post electroporation for both homogenous B16 melanoma and heterogeneous human serum derived populations of exosomes. Moreover, TPM enabled heavy cargo loading of melanoma exosomes with 5 nm superparamagnetic iron oxide nanoparticles (SPION5) while maintaining original exosome size and minimizing exosome aggregation as evidenced by transmission electron microscopy. Loading exosomes with SPION5 increased exosome density on sucrose gradients. This provides a simple, label free means to enrich exogenously modified exosomes and introduces the potential for MRI driven theranostic exosome investigations in vivo. PMID:24333249

  18. Optimal topologies for maximizing network transmission capacity

    Science.gov (United States)

    Chen, Zhenhao; Wu, Jiajing; Rong, Zhihai; Tse, Chi K.

    2018-04-01

    It has been widely demonstrated that the structure of a network is a major factor that affects its traffic dynamics. In this work, we try to identify the optimal topologies for maximizing the network transmission capacity, as well as to build a clear relationship between structural features of a network and the transmission performance in terms of traffic delivery. We propose an approach for designing optimal network topologies against traffic congestion by link rewiring and apply them on the Barabási-Albert scale-free, static scale-free and Internet Autonomous System-level networks. Furthermore, we analyze the optimized networks using complex network parameters that characterize the structure of networks, and our simulation results suggest that an optimal network for traffic transmission is more likely to have a core-periphery structure. However, assortative mixing and the rich-club phenomenon may have negative impacts on network performance. Based on the observations of the optimized networks, we propose an efficient method to improve the transmission capacity of large-scale networks.

  19. Lower skin temperature decreases maximal cycling performance.

    Science.gov (United States)

    Imai, Daiki; Okazaki, Kazunobu; Matsumura, Shinya; Suzuki, Takashi; Miyazawa, Taiki; Suzuki, Akina; Takeda, Ryosuke; Hamamoto, Takeshi; Zako, Tetsuo; Kawabata, Takashi; Miyagawa, Toshiaki

    2011-12-01

    It is known that external cooling of body regions involved in exercise, prior to exercise, decreases anaerobic performance. However, there have been no studies reporting the effects of whole body skin surface cooling before exercise on maximal anaerobic capacity. In order to clarify the effects, we compared power output during the Wingate anaerobic test between preconditioning by exposure to temperature 10 degrees C and 25 degrees C. Eight healthy males carried out the Wingate test for 30 seconds, after pre-conditioning for 60 minutes using a perfusion suit with water at a temperature of 10 degrees C or 25 degrees C. We evaluated the peak power (PP) and peak power slope (PS) of the power output. Mean skin temperature (T(sk)) at 60 minutes of pre-conditioning in the 10 degrees C trial was significantly lower than in the 25 degrees C trial (p < 0.05). PP and also PS were significantly lower in the 10 degrees C trial than in the 25 degrees C trial. Changes (Δ) in PP between the 10 degrees C trial and the 25 degrees C trial were strongly correlated with ΔT(sk) and Δ in thigh and leg skin temperature (ΔT(thigh) and ΔT(leg), respectively), whereas ΔPS was strongly correlated with ΔT(sk), but not with ΔT(thigh) and ΔT(leg). Whole body skin surface cooling prior to exercise restricts anaerobic capacity, especially in the initial phase of exercise.

  20. Value maximizing maintenance policies under general repair

    International Nuclear Information System (INIS)

    Marais, Karen B.

    2013-01-01

    One class of maintenance optimization problems considers the notion of general repair maintenance policies where systems are repaired or replaced on failure. In each case the optimality is based on minimizing the total maintenance cost of the system. These cost-centric optimizations ignore the value dimension of maintenance and can lead to maintenance strategies that do not maximize system value. This paper applies these ideas to the general repair optimization problem using a semi-Markov decision process, discounted cash flow techniques, and dynamic programming to identify the value-optimal actions for any given time and system condition. The impact of several parameters on maintenance strategy, such as operating cost and revenue, system failure characteristics, repair and replacement costs, and the planning time horizon, is explored. This approach provides a quantitative basis on which to base maintenance strategy decisions that contribute to system value. These decisions are different from those suggested by traditional cost-based approaches. The results show (1) how the optimal action for a given time and condition changes as replacement and repair costs change, and identifies the point at which these costs become too high for profitable system operation; (2) that for shorter planning horizons it is better to repair, since there is no time to reap the benefits of increased operating profit and reliability; (3) how the value-optimal maintenance policy is affected by the system's failure characteristics, and hence whether it is worthwhile to invest in higher reliability; and (4) the impact of the repair level on the optimal maintenance policy. -- Highlights: •Provides a quantitative basis for maintenance strategy decisions that contribute to system value. •Shows how the optimal action for a given condition changes as replacement and repair costs change. •Shows how the optimal policy is affected by the system's failure characteristics. •Shows when it is

  1. Independent component analysis for brain FMRI does indeed select for maximal independence.

    Directory of Open Access Journals (Sweden)

    Vince D Calhoun

    Full Text Available A recent paper by Daubechies et al. claims that two independent component analysis (ICA algorithms, Infomax and FastICA, which are widely used for functional magnetic resonance imaging (fMRI analysis, select for sparsity rather than independence. The argument was supported by a series of experiments on synthetic data. We show that these experiments fall short of proving this claim and that the ICA algorithms are indeed doing what they are designed to do: identify maximally independent sources.

  2. POLITENESS MAXIM OF MAIN CHARACTER IN SECRET FORGIVEN

    Directory of Open Access Journals (Sweden)

    Sang Ayu Isnu Maharani

    2017-06-01

    Full Text Available Maxim of Politeness is an interesting subject to be discussed, since politeness has been criticized from our childhood. We are obliques to be polite to anyone either in speaking or in acting. Somehow we are manage to show politeness in our spoken expression though our intention might be not so polite. For example we must appriciate others opinion although we feel objection toward the opinion. In this article the analysis of politeness is based on maxim proposes by Leech. He proposed six types of politeness maxim. The discussion shows that the main character (Kristen and Kami use all types of maxim in their conversation. The most commonly used are approbation maxim and agreement maxim

  3. Shareholder, stakeholder-owner or broad stakeholder maximization

    DEFF Research Database (Denmark)

    Mygind, Niels

    2004-01-01

    including the shareholders of a company. Although it may be the ultimate goal for Corporate Social Responsibility to achieve this kind of maximization, broad stakeholder maximization is quite difficult to give a precise definition. There is no one-dimensional measure to add different stakeholder benefits...... by other stakeholders' interests. These constraints vary for dif-ferent stakeholder owners and new standards for Corporate Social Responsibility and more active political consumers will strengthen these constraints.......With reference to the discussion about shareholder versus stakeholder maximization it is argued that the normal type of maximization is in fact stakeholder-owner maxi-mization. This means maximization of the sum of the value of the shares and stake-holder benefits belonging to the dominating...

  4. Fractional maximal function and its commutators on Orlicz spaces

    Science.gov (United States)

    Guliyev, Vagif S.; Deringoz, Fatih; Hasanov, Sabir G.

    2017-08-01

    In this paper, we find necessary and sufficient conditions for the boundedness of fractional maximal operator M_{α } on Orlicz spaces. As an application of this results we consider the boundedness of fractional maximal commutator M_{b,α } and nonlinear commutator of fractional maximal operator [b,M_{α }] on Orlicz spaces, when b belongs to the Lipschitz space, by which some new characterizations of the Lipschitz spaces are given.

  5. Maximize Performance Impact: Create Partnerships with Customers.

    Science.gov (United States)

    Stevens, Judith; Ibanez, Barbara

    2001-01-01

    Discusses how to improve organizational performance by involving customers in partnerships. Relates experiences at the Center for Development and Disability at the University of New Mexico, serving people with developmental disabilities, which helped realize their mission, helped staff cross from theory to application, and increased relevancy and…

  6. When Wanting the Best Goes Right or Wrong: Distinguishing Between Adaptive and Maladaptive Maximization.

    Science.gov (United States)

    Hughes, Jeffrey; Scholer, Abigail A

    2017-04-01

    Researchers have often disagreed on how to define maximization, leading to conflicting conclusions about its potential benefits or drawbacks. Drawing from motivation research, we distinguish between the goals (i.e., wanting the best) and strategies (e.g., alternative search) associated with maximizing. Three studies illustrate how this differentiation offers insight into when maximizers do or do not experience affective costs when making decisions. In Study 1, we show that two motivational orientations, promotion focus and assessment mode, are both associated with the goal of wanting the best, yet assessment (not promotion) is related to the use of alternative search strategies. In Study 2, we demonstrate that alternative search strategies are associated with frustration on a discrete decision task. In Study 3, we provide evidence that one reason for this link may be due to reconsideration of previously dismissed options. We discuss the potential of this approach to integrate research in this area.

  7. Violating Bell inequalities maximally for two d-dimensional systems

    International Nuclear Information System (INIS)

    Chen Jingling; Wu Chunfeng; Oh, C. H.; Kwek, L. C.; Ge Molin

    2006-01-01

    We show the maximal violation of Bell inequalities for two d-dimensional systems by using the method of the Bell operator. The maximal violation corresponds to the maximal eigenvalue of the Bell operator matrix. The eigenvectors corresponding to these eigenvalues are described by asymmetric entangled states. We estimate the maximum value of the eigenvalue for large dimension. A family of elegant entangled states |Ψ> app that violate Bell inequality more strongly than the maximally entangled state but are somewhat close to these eigenvectors is presented. These approximate states can potentially be useful for quantum cryptography as well as many other important fields of quantum information

  8. Social Customer Relationship Management : Maximizing Customer Relationships

    OpenAIRE

    Leino, Jarkko

    2016-01-01

    The Internet and digitalization have changed the buying behaviour of customers and challenged businesses to create new ways to bring value to their customers. Old ways of mass mailing, pushy advertisements and cold calls are vanishing from the scene as they are only disturbing the customers and adding bringing value. The modern customer is intelligent and demanding individual who is making the decisions using lots of information and seeking experiences to fulfil their expectations. Sales ...

  9. Alternative approaches to maximally supersymmetric field theories

    International Nuclear Information System (INIS)

    Broedel, Johannes

    2010-01-01

    The central objective of this work is the exploration and application of alternative possibilities to describe maximally supersymmetric field theories in four dimensions: N=4 super Yang-Mills theory and N=8 supergravity. While twistor string theory has been proven very useful in the context of N=4 SYM, no analogous formulation for N=8 supergravity is available. In addition to the part describing N=4 SYM theory, twistor string theory contains vertex operators corresponding to the states of N=4 conformal supergravity. Those vertex operators have to be altered in order to describe (non-conformal) Einstein supergravity. A modified version of the known open twistor string theory, including a term which breaks the conformal symmetry for the gravitational vertex operators, has been proposed recently. In a first part of the thesis structural aspects and consistency of the modified theory are discussed. Unfortunately, the majority of amplitudes can not be constructed, which can be traced back to the fact that the dimension of the moduli space of algebraic curves in twistor space is reduced in an inconsistent manner. The issue of a possible finiteness of N=8 supergravity is closely related to the question of the existence of valid counterterms in the perturbation expansion of the theory. In particular, the coefficient in front of the so-called R 4 counterterm candidate has been shown to vanish by explicit calculation. This behavior points into the direction of a symmetry not taken into account, for which the hidden on-shell E 7(7) symmetry is the prime candidate. The validity of the so-called double-soft scalar limit relation is a necessary condition for a theory exhibiting E 7(7) symmetry. By calculating the double-soft scalar limit for amplitudes derived from an N=8 supergravity action modified by an additional R 4 counterterm, one can test for possible constraints originating in the E 7(7) symmetry. In a second part of the thesis, the appropriate amplitudes are calculated

  10. Detrimental Relations of Maximization with Academic and Career Attitudes

    Science.gov (United States)

    Dahling, Jason J.; Thompson, Mindi N.

    2013-01-01

    Maximization refers to a decision-making style that involves seeking the single best option when making a choice, which is generally dysfunctional because people are limited in their ability to rationally evaluate all options and identify the single best outcome. The vocational consequences of maximization are examined in two samples, college…

  11. An Overview of Maximal Unitarity at Two Loops

    CERN Document Server

    Johansson, Henrik; Larsen, Kasper J.

    2012-01-01

    We discuss the extension of the maximal-unitarity method to two loops, focusing on the example of the planar double box. Maximal cuts are reinterpreted as contour integrals, with the choice of contour fixed by the requirement that integrals of total derivatives vanish on it. The resulting formulae, like their one-loop counterparts, can be applied either analytically or numerically.

  12. Utility maximization under solvency constraints and unhedgeable risks

    NARCIS (Netherlands)

    Kleinow, T.; Pelsser, A.

    2008-01-01

    We consider the utility maximization problem for an investor who faces a solvency or risk constraint in addition to a budget constraint. The investor wishes to maximize her expected utility from terminal wealth subject to a bound on her expected solvency at maturity. We measure solvency using a

  13. Shareholder, stakeholder-owner or broad stakeholder maximization

    DEFF Research Database (Denmark)

    Mygind, Niels

    2004-01-01

    including the shareholders of a company. Although it may be the ultimate goal for Corporate Social Responsibility to achieve this kind of maximization, broad stakeholder maximization is quite difficult to give a precise definition. There is no one-dimensional measure to add different stakeholder benefits...

  14. Maximal saddle solution of a nonlinear elliptic equation involving the ...

    Indian Academy of Sciences (India)

    Abstract. A saddle solution is called maximal saddle solution if its absolute value is not smaller than those absolute values of any solutions that vanish on the Simons cone. C = {s = t} and have the same sign as s − t. We prove the existence of a maximal saddle solution of the nonlinear elliptic equation involving the ...

  15. On Horowitz and Shelah's Borel maximal eventually different family

    DEFF Research Database (Denmark)

    Schrittesser, David

    2017-01-01

    We give an exposition of Horowitz and Shelah’s proof that there exists an effectively Borel maximal eventually different family (working in ZF or less) and announce two related theorems.......We give an exposition of Horowitz and Shelah’s proof that there exists an effectively Borel maximal eventually different family (working in ZF or less) and announce two related theorems....

  16. Pace's Maxims for Homegrown Library Projects. Coming Full Circle

    Science.gov (United States)

    Pace, Andrew K.

    2005-01-01

    This article discusses six maxims by which to run library automation. The following maxims are discussed: (1) Solve only known problems; (2) Avoid changing data to fix display problems; (3) Aut viam inveniam aut faciam; (4) If you cannot make it yourself, buy something; (5) Kill the alligator closest to the boat; and (6) Just because yours is…

  17. Pollination benefits are maximized at intermediate nutrient levels.

    Science.gov (United States)

    Tamburini, Giovanni; Lami, Francesco; Marini, Lorenzo

    2017-08-16

    Yield production in flowering crops depends on both nutrient availability and pollination, but their relative roles and potential interactions are poorly understood. We measured pollination benefits to yield in sunflower, combining a gradient in insect pollination (0, 25, 50, 100%) with a continuous gradient in nitrogen (N) fertilization (from 0 to 150 kg N ha -1 ) in an experiment under realistic soil field conditions. We found that pollination benefits to yield were maximized at intermediate levels of N availability, bolstering yield by approximately 25% compared with complete pollinator exclusion. Interestingly, we found little decrease in yield when insect visits were reduced by 50%, indicating that the incremental contribution of pollination by insects to yield is greater when the baseline pollination service provision is very low. Our findings provide strong evidence for interactive, nonlinear effects of pollination and resource availability on seed production. Our results support ecological intensification as a promising strategy for sustainable management of agroecosystems. In particular, we found optimal level of pollination to potentially compensate for lower N applications. © 2017 The Author(s).

  18. Maximizing industrial infrastructure efficiency in Iceland

    Science.gov (United States)

    Ingason, Helgi Thor; Sigfusson, Thorsteinn I.

    2010-08-01

    As a consequence of the increasing aluminum production in Iceland, local processing of aluminum skimmings has become a feasible business opportunity. A recycling plant for this purpose was built in Helguvik on the Reykjanes peninsula in 2003. The case of the recycling plant reflects increased concern regarding environmental aspects of the industry. An interesting characteristic of this plant is the fact that it is run in the same facilities as a large fishmeal production installation. It is operated by the same personnel and uses—partly—the same equipment and infrastructure. This paper reviews the grounds for these decisions and the experience of this merger of a traditional fish melting industry and a more recent aluminum melting industry after 6 years of operation. The paper is written by the original entrepreneurs behind the company, who provide observations on how the aluminum industry in Iceland has evolved since the starting of Alur’s operation and what might be expected in the near future.

  19. Maximizing value for planned maintenance and turnarounds

    Energy Technology Data Exchange (ETDEWEB)

    Crager, John [Asset Performance Canada, ULC (Canada)

    2011-07-01

    In this presentation, Asset Performance Canada elaborates on turnaround management, and provides insight into managing strategies and risks associated with turnaround processes. Value is created fast as turnarounds progress from the strategy and scope definition phases towards the planning and execution phases. Turnarounds employ best practice solutions through common processes proven effective by data, research, and experience, ensuring consistent value creation, performance tracking, and shared lesson-learning. Adherence to the turnaround work process by carefully selected planning team members with clearly defined responsibilities and expectations, as well as an effective process for scope collection and management, are crucial to turnaround success. Further to this, a formal risk management process, employing automated risk tracking software and a safety management plan for assessing risks and their severity is also invaluable in avoiding any additional costs and schedule delays. Finally, assessment of team readiness and alignment through use of the turnaround readiness index, and rapid management of discovery work, can aid in contingency management.

  20. Maximizing noise energy for noise-masking studies.

    Science.gov (United States)

    Jules Étienne, Cédric; Arleo, Angelo; Allard, Rémy

    2017-08-01

    Noise-masking experiments are widely used to investigate visual functions. To be useful, noise generally needs to be strong enough to noticeably impair performance, but under some conditions, noise does not impair performance even when its contrast approaches the maximal displayable limit of 100 %. To extend the usefulness of noise-masking paradigms over a wider range of conditions, the present study developed a noise with great masking strength. There are two typical ways of increasing masking strength without exceeding the limited contrast range: use binary noise instead of Gaussian noise or filter out frequencies that are not relevant to the task (i.e., which can be removed without affecting performance). The present study combined these two approaches to further increase masking strength. We show that binarizing the noise after the filtering process substantially increases the energy at frequencies within the pass-band of the filter given equated total contrast ranges. A validation experiment showed that similar performances were obtained using binarized-filtered noise and filtered noise (given equated noise energy at the frequencies within the pass-band) suggesting that the binarization operation, which substantially reduced the contrast range, had no significant impact on performance. We conclude that binarized-filtered noise (and more generally, truncated-filtered noise) can substantially increase the energy of the noise at frequencies within the pass-band. Thus, given a limited contrast range, binarized-filtered noise can display higher energy levels than Gaussian noise and thereby widen the range of conditions over which noise-masking paradigms can be useful.

  1. Inquiry in bibliography some of the bustan`s maxim

    Directory of Open Access Journals (Sweden)

    sajjad rahmatian

    2016-12-01

    Full Text Available Sa`di is on of those poets who`s has placed a special position to preaching and guiding the people and among his works, allocated throughout the text of bustan to advice and maxim on legal and ethical various subjects. Surely, sa`di on the way of to compose this work and expression of its moral point, direct or indirect have been affected by some previous sources and possibly using their content. The main purpose of this article is that the pay review of basis and sources of bustan`s maxims and show that sa`di when expression the maxims of this work has been affected by which of the texts and works. For this purpose is tried to with search and research on the resources that have been allocated more or less to the aphorisms, to discover and extract traces of influence sa`di from their moral and didactic content. From the most important the finding of this study can be mentioned that indirect effect of some pahlavi books of maxim (like maxims of azarbad marespandan and bozorgmehr book of maxim and also noted sa`di directly influenced of moral and ethical works of poets and writers before him, and of this, sa`di`s influence from abo- shakur balkhi maxims, ferdowsi and keikavus is remarkable and noteworthy.

  2. Maximal exercise and acute mood response in women.

    Science.gov (United States)

    Pronk, N P; Crouse, S F; Rohack, J J

    1995-01-01

    The present study was designed to characterize and assess the reliability of acute mood responses to maximal exercise in women. All subjects (N = 22; age = 45 +/- 2.5 yr; BMI = 24.3 +/- 0.9 kg/m2) participated in two maximal walking tests spaced approximately one month apart. The abbreviated Profile of Mood States (POMS) questionnaire was administered immediately prior to and within 5 min following maximal exercise at both occasions. Maximal heart rate, rating of perceived exertion, and functional aerobic capacity responses indicated compliance to maximal exertion at both tests. Using repeated measures ANOVA, no significant (p self-esteem subscales while the tension and vigor affects significantly decreased. Because no interactions were found, these effects are concluded to be independent of the order in which the tests were performed. Additionally, intraclass correlations computed for each respective POMS subscale, ranged between 0.69 and 0.81 for fatigue, tension, vigor, self-esteem, confusion, and total mood disturbance. The anger and depression subscales were noted to have intraclass correlations of 0.29 and 0.43, respectively, and may have been influenced by a floor effect in this study population. It is concluded that the abbreviated POMS questionnaire may be reliably used to assess acute mood responses to maximal exercise in women and that even maximal exertion has the potential to acutely benefit mood by decreasing tension and increasing self-esteem.

  3. Optimal quantum error correcting codes from absolutely maximally entangled states

    Science.gov (United States)

    Raissi, Zahra; Gogolin, Christian; Riera, Arnau; Acín, Antonio

    2018-02-01

    Absolutely maximally entangled (AME) states are pure multi-partite generalizations of the bipartite maximally entangled states with the property that all reduced states of at most half the system size are in the maximally mixed state. AME states are of interest for multipartite teleportation and quantum secret sharing and have recently found new applications in the context of high-energy physics in toy models realizing the AdS/CFT-correspondence. We work out in detail the connection between AME states of minimal support and classical maximum distance separable (MDS) error correcting codes and, in particular, provide explicit closed form expressions for AME states of n parties with local dimension \

  4. Maximizing information exchange between complex networks

    International Nuclear Information System (INIS)

    West, Bruce J.; Geneston, Elvis L.; Grigolini, Paolo

    2008-01-01

    Science is not merely the smooth progressive interaction of hypothesis, experiment and theory, although it sometimes has that form. More realistically the scientific study of any given complex phenomenon generates a number of explanations, from a variety of perspectives, that eventually requires synthesis to achieve a deep level of insight and understanding. One such synthesis has created the field of out-of-equilibrium statistical physics as applied to the understanding of complex dynamic networks. Over the past forty years the concept of complexity has undergone a metamorphosis. Complexity was originally seen as a consequence of memory in individual particle trajectories, in full agreement with a Hamiltonian picture of microscopic dynamics and, in principle, macroscopic dynamics could be derived from the microscopic Hamiltonian picture. The main difficulty in deriving macroscopic dynamics from microscopic dynamics is the need to take into account the actions of a very large number of components. The existence of events such as abrupt jumps, considered by the conventional continuous time random walk approach to describing complexity was never perceived as conflicting with the Hamiltonian view. Herein we review many of the reasons why this traditional Hamiltonian view of complexity is unsatisfactory. We show that as a result of technological advances, which make the observation of single elementary events possible, the definition of complexity has shifted from the conventional memory concept towards the action of non-Poisson renewal events. We show that the observation of crucial processes, such as the intermittent fluorescence of blinking quantum dots as well as the brain's response to music, as monitored by a set of electrodes attached to the scalp, has forced investigators to go beyond the traditional concept of complexity and to establish closer contact with the nascent field of complex networks. Complex networks form one of the most challenging areas of modern

  5. Maximizing information exchange between complex networks

    Energy Technology Data Exchange (ETDEWEB)

    West, Bruce J. [Mathematical and Information Science, Army Research Office, Research Triangle Park, NC 27708 (United States); Physics Department, Duke University, Durham, NC 27709 (United States)], E-mail: bwest@nc.rr.com; Geneston, Elvis L. [Center for Nonlinear Science, University of North Texas, P.O. Box 311427, Denton, TX 76203-1427 (United States); Physics Department, La Sierra University, 4500 Riverwalk Parkway, Riverside, CA 92515 (United States); Grigolini, Paolo [Center for Nonlinear Science, University of North Texas, P.O. Box 311427, Denton, TX 76203-1427 (United States); Istituto di Processi Chimico Fisici del CNR, Area della Ricerca di Pisa, Via G. Moruzzi, 56124, Pisa (Italy); Dipartimento di Fisica ' E. Fermi' Universita' di Pisa, Largo Pontecorvo 3, 56127 Pisa (Italy)

    2008-10-15

    Science is not merely the smooth progressive interaction of hypothesis, experiment and theory, although it sometimes has that form. More realistically the scientific study of any given complex phenomenon generates a number of explanations, from a variety of perspectives, that eventually requires synthesis to achieve a deep level of insight and understanding. One such synthesis has created the field of out-of-equilibrium statistical physics as applied to the understanding of complex dynamic networks. Over the past forty years the concept of complexity has undergone a metamorphosis. Complexity was originally seen as a consequence of memory in individual particle trajectories, in full agreement with a Hamiltonian picture of microscopic dynamics and, in principle, macroscopic dynamics could be derived from the microscopic Hamiltonian picture. The main difficulty in deriving macroscopic dynamics from microscopic dynamics is the need to take into account the actions of a very large number of components. The existence of events such as abrupt jumps, considered by the conventional continuous time random walk approach to describing complexity was never perceived as conflicting with the Hamiltonian view. Herein we review many of the reasons why this traditional Hamiltonian view of complexity is unsatisfactory. We show that as a result of technological advances, which make the observation of single elementary events possible, the definition of complexity has shifted from the conventional memory concept towards the action of non-Poisson renewal events. We show that the observation of crucial processes, such as the intermittent fluorescence of blinking quantum dots as well as the brain's response to music, as monitored by a set of electrodes attached to the scalp, has forced investigators to go beyond the traditional concept of complexity and to establish closer contact with the nascent field of complex networks. Complex networks form one of the most challenging areas of

  6. Maximizing information exchange between complex networks

    Science.gov (United States)

    West, Bruce J.; Geneston, Elvis L.; Grigolini, Paolo

    2008-10-01

    Science is not merely the smooth progressive interaction of hypothesis, experiment and theory, although it sometimes has that form. More realistically the scientific study of any given complex phenomenon generates a number of explanations, from a variety of perspectives, that eventually requires synthesis to achieve a deep level of insight and understanding. One such synthesis has created the field of out-of-equilibrium statistical physics as applied to the understanding of complex dynamic networks. Over the past forty years the concept of complexity has undergone a metamorphosis. Complexity was originally seen as a consequence of memory in individual particle trajectories, in full agreement with a Hamiltonian picture of microscopic dynamics and, in principle, macroscopic dynamics could be derived from the microscopic Hamiltonian picture. The main difficulty in deriving macroscopic dynamics from microscopic dynamics is the need to take into account the actions of a very large number of components. The existence of events such as abrupt jumps, considered by the conventional continuous time random walk approach to describing complexity was never perceived as conflicting with the Hamiltonian view. Herein we review many of the reasons why this traditional Hamiltonian view of complexity is unsatisfactory. We show that as a result of technological advances, which make the observation of single elementary events possible, the definition of complexity has shifted from the conventional memory concept towards the action of non-Poisson renewal events. We show that the observation of crucial processes, such as the intermittent fluorescence of blinking quantum dots as well as the brain’s response to music, as monitored by a set of electrodes attached to the scalp, has forced investigators to go beyond the traditional concept of complexity and to establish closer contact with the nascent field of complex networks. Complex networks form one of the most challenging areas of

  7. Rational maximizing by humans (Homo sapiens) in an ultimatum game.

    Science.gov (United States)

    Smith, Phillip; Silberberg, Alan

    2010-07-01

    In the human mini-ultimatum game, a proposer splits a sum of money with a responder. If the responder accepts, both are paid. If not, neither is paid. Typically, responders reject inequitable distributions, favoring punishing over maximizing. In Jensen et al.'s (Science 318:107-109, 2007) adaptation with apes, a proposer selects between two distributions of raisins. Despite inequitable offers, responders often accept, thereby maximizing. The rejection response differs between the human and ape versions of this game. For humans, rejection is instantaneous; for apes, it requires 1 min of inaction. We replicate Jensen et al.'s procedure in humans with money. When waiting 1 min to reject, humans favor punishing over maximizing; however, when rejection requires 5 min of inaction, humans, like apes, maximize. If species differences in time horizons are accommodated, Jensen et al.'s ape data are reproducible in humans.

  8. Reference Values for Maximal Inspiratory Pressure: A Systematic Review

    Directory of Open Access Journals (Sweden)

    Isabela MB Sclauser Pessoa

    2014-01-01

    Full Text Available BACKGROUND: Maximal inspiratory pressure (MIP is the most commonly used measure to evaluate inspiratory muscle strength. Normative values for MIP vary significantly among studies, which may reflect differences in participant demographics and technique of MIP measurement.

  9. Power Converters Maximize Outputs Of Solar Cell Strings

    Science.gov (United States)

    Frederick, Martin E.; Jermakian, Joel B.

    1993-01-01

    Microprocessor-controlled dc-to-dc power converters devised to maximize power transferred from solar photovoltaic strings to storage batteries and other electrical loads. Converters help in utilizing large solar photovoltaic arrays most effectively with respect to cost, size, and weight. Main points of invention are: single controller used to control and optimize any number of "dumb" tracker units and strings independently; power maximized out of converters; and controller in system is microprocessor.

  10. Trainability of Muscular Activity Level during Maximal Voluntary Co-Contraction: Comparison between Bodybuilders and Nonathletes

    Science.gov (United States)

    Maeo, Sumiaki; Takahashi, Takumi; Takai, Yohei; Kanehisa, Hiroaki

    2013-01-01

    Antagonistic muscle pairs cannot be fully activated simultaneously, even with maximal effort, under conditions of voluntary co-contraction, and their muscular activity levels are always below those during agonist contraction with maximal voluntary effort (MVE). Whether the muscular activity level during the task has trainability remains unclear. The present study examined this issue by comparing the muscular activity level during maximal voluntary co-contraction for highly experienced bodybuilders, who frequently perform voluntary co-contraction in their training programs, with that for untrained individuals (nonathletes). The electromyograms (EMGs) of biceps brachii and triceps brachii muscles during maximal voluntary co-contraction of elbow flexors and extensors were recorded in 11 male bodybuilders and 10 nonathletes, and normalized to the values obtained during the MVE of agonist contraction for each of the corresponding muscles (% EMGMVE). The involuntary coactivation level in antagonist muscle during the MVE of agonist contraction was also calculated. In both muscles, % EMGMVE values during the co-contraction task for bodybuilders were significantly higher (Pbodybuilders vs. 46±13% in nonathletes, triceps brachii: 74±16% vs. 57±9%). There was a significant positive correlation between a length of bodybuilding experience and muscular activity level during the co-contraction task (r = 0.653, P = 0.03). Involuntary antagonist coactivation level during MVE of agonist contraction was not different between the two groups. The current result indicates that long-term participation in voluntary co-contraction training progressively enhances muscular activity during maximal voluntary co-contraction. PMID:24260233

  11. Trainability of muscular activity level during maximal voluntary co-contraction: comparison between bodybuilders and nonathletes.

    Directory of Open Access Journals (Sweden)

    Sumiaki Maeo

    Full Text Available Antagonistic muscle pairs cannot be fully activated simultaneously, even with maximal effort, under conditions of voluntary co-contraction, and their muscular activity levels are always below those during agonist contraction with maximal voluntary effort (MVE. Whether the muscular activity level during the task has trainability remains unclear. The present study examined this issue by comparing the muscular activity level during maximal voluntary co-contraction for highly experienced bodybuilders, who frequently perform voluntary co-contraction in their training programs, with that for untrained individuals (nonathletes. The electromyograms (EMGs of biceps brachii and triceps brachii muscles during maximal voluntary co-contraction of elbow flexors and extensors were recorded in 11 male bodybuilders and 10 nonathletes, and normalized to the values obtained during the MVE of agonist contraction for each of the corresponding muscles (% EMGMVE. The involuntary coactivation level in antagonist muscle during the MVE of agonist contraction was also calculated. In both muscles, % EMGMVE values during the co-contraction task for bodybuilders were significantly higher (P<0.01 than those for nonathletes (biceps brachii: 66±14% in bodybuilders vs. 46±13% in nonathletes, triceps brachii: 74±16% vs. 57±9%. There was a significant positive correlation between a length of bodybuilding experience and muscular activity level during the co-contraction task (r = 0.653, P = 0.03. Involuntary antagonist coactivation level during MVE of agonist contraction was not different between the two groups. The current result indicates that long-term participation in voluntary co-contraction training progressively enhances muscular activity during maximal voluntary co-contraction.

  12. Correlation Between Abdominal Muscle Thickness and Maximal Expiratory Pressure.

    Science.gov (United States)

    Ishida, Hiroshi; Suehiro, Tadanobu; Kurozumi, Chiharu; Ono, Koji; Watanabe, Susumu

    2015-11-01

    The activity of abdominal muscles mainly produces high expiratory pressure. These include the rectus abdominis, external oblique, internal oblique, and transverse abdominis muscles. The purpose of this study was to determine whether maximal expiratory pressure is associated with each abdominal muscle thickness at rest. Thirty-nine healthy male volunteers (mean age ± SD, 20.7 ± 2.7 years) participated in the study. The thickness of the right rectus abdominis, external oblique, internal oblique, and transverse abdominis muscles was measured by B-mode sonography in the supine position. The maximal expiratory pressure was obtained with a spirometer in the sitting position. The correlations between each abdominal muscle thickness and maximal expiratory pressure were determined by the Pearson correlation coefficient. The correlation coefficient between the rectus abdominis muscle and maximal expiratory pressure was 0.571 (Pmuscles and maximal expiratory pressure were 0.297 (P = .066), 0.267 (P = .100), and 0.022 (P = .894), respectively. Our results indicate that the rectus abdominis muscle thickness might be more highly correlated with expiratory pressure production than the external oblique, internal oblique, and transverse abdominis muscle thickness. © 2015 by the American Institute of Ultrasound in Medicine.

  13. Maximizing power production in a stack of microbial fuel cells using multiunit optimization method.

    Science.gov (United States)

    Woodward, Lyne; Perrier, Michel; Srinivasan, Bala; Tartakovsky, Boris

    2009-01-01

    This study demonstrates real-time maximization of power production in a stack of two continuous flow microbial fuel cells (MFCs). To maximize power output, external resistances of two air-cathode membraneless MFCs were controlled by a multiunit optimization algorithm. Multiunit optimization is a recently proposed method that uses multiple similar units to optimize process performance. The experiment demonstrated fast convergence toward optimal external resistance and algorithm stability during external perturbations (e.g., temperature variations). Rate of the algorithm convergence was much faster than in traditional maximum power point tracking algorithms (MPPT), which are based on temporal perturbations. A power output of 81-84 mW/L(A) (A = anode volume) was achieved in each MFC. 2009 American Institute of Chemical Engineers

  14. Aging and loss decision making: increased risk aversion and decreased use of maximizing information, with correlated rationality and value maximization.

    Science.gov (United States)

    Kurnianingsih, Yoanna A; Sim, Sam K Y; Chee, Michael W L; Mullette-Gillman, O'Dhaniel A

    2015-01-01

    We investigated how adult aging specifically alters economic decision-making, focusing on examining alterations in uncertainty preferences (willingness to gamble) and choice strategies (what gamble information influences choices) within both the gains and losses domains. Within each domain, participants chose between certain monetary outcomes and gambles with uncertain outcomes. We examined preferences by quantifying how uncertainty modulates choice behavior as if altering the subjective valuation of gambles. We explored age-related preferences for two types of uncertainty, risk, and ambiguity. Additionally, we explored how aging may alter what information participants utilize to make their choices by comparing the relative utilization of maximizing and satisficing information types through a choice strategy metric. Maximizing information was the ratio of the expected value of the two options, while satisficing information was the probability of winning. We found age-related alterations of economic preferences within the losses domain, but no alterations within the gains domain. Older adults (OA; 61-80 years old) were significantly more uncertainty averse for both risky and ambiguous choices. OA also exhibited choice strategies with decreased use of maximizing information. Within OA, we found a significant correlation between risk preferences and choice strategy. This linkage between preferences and strategy appears to derive from a convergence to risk neutrality driven by greater use of the effortful maximizing strategy. As utility maximization and value maximization intersect at risk neutrality, this result suggests that OA are exhibiting a relationship between enhanced rationality and enhanced value maximization. While there was variability in economic decision-making measures within OA, these individual differences were unrelated to variability within examined measures of cognitive ability. Our results demonstrate that aging alters economic decision-making for

  15. Aging and loss decision making: increased risk aversion and decreased use of maximizing information, with correlated rationality and value maximization

    Directory of Open Access Journals (Sweden)

    Yoanna Arlina Kurnianingsih

    2015-05-01

    Full Text Available We investigated how adult aging specifically alters economic decision-making, focusing on examining alterations in uncertainty preferences (willingness to gamble and choice strategies (what gamble information influences choices within both the gains and losses domains. Within each domain, participants chose between certain monetary outcomes and gambles with uncertain outcomes. We examined preferences by quantifying how uncertainty modulates choice behavior as if altering the subjective valuation of gambles. We explored age-related preferences for two types of uncertainty, risk and ambiguity. Additionally, we explored how aging may alter what information participants utilize to make their choices by comparing the relative utilization of maximizing and satisficing information types through a choice strategy metric. Maximizing information was the ratio of the expected value of the two options, while satisficing information was the probability of winning.We found age-related alterations of economic preferences within the losses domain, but no alterations within the gains domain. Older adults (OA; 61 to 80 years old were significantly more uncertainty averse for both risky and ambiguous choices. OA also exhibited choice strategies with decreased use of maximizing information. Within OA, we found a significant correlation between risk preferences and choice strategy. This linkage between preferences and strategy appears to derive from a convergence to risk neutrality driven by greater use of the effortful maximizing strategy. As utility maximization and value maximization intersect at risk neutrality, this result suggests that OA are exhibiting a relationship between enhanced rationality and enhanced value maximization. While there was variability in economic decision-making measures within OA, these individual differences were unrelated to variability within examined measures of cognitive ability. Our results demonstrate that aging alters economic

  16. Cross-Order Integral Relations from Maximal Cuts

    CERN Document Server

    Johansson, Henrik; Larsen, Kasper J.; Søgaard, Mads

    2015-01-01

    We study the ABDK relation using maximal cuts of one- and two-loop integrals with up to five external legs. We show how to find a special combination of integrals that allows the relation to exist, and how to reconstruct the terms with one-loop integrals squared. The reconstruction relies on the observation that integrals across different loop orders can have support on the same generalized unitarity cuts and can share global poles. We discuss the appearance of nonhomologous integration contours in multivariate residues. Their origin can be understood in simple terms, and their existence enables us to distinguish contributions from different integrals. Our analysis suggests that maximal and near-maximal cuts can be used to infer the existence of integral identities more generally.

  17. Maximal Electric Dipole Moments of Nuclei with Enhanced Schiff Moments

    CERN Document Server

    Ellis, John; Pilaftsis, Apostolos

    2011-01-01

    The electric dipole moments (EDMs) of heavy nuclei, such as 199Hg, 225Ra and 211Rn, can be enhanced by the Schiff moments induced by the presence of nearby parity-doublet states. Working within the framework of the maximally CP-violating and minimally flavour-violating (MCPMFV) version of the MSSM, we discuss the maximal values that such EDMs might attain, given the existing experimental constraints on the Thallium, neutron and Mercury EDMs. The maximal EDM values of the heavy nuclei are obtained with the help of a differential-geometrical approach proposed recently that enables the maxima of new CP-violating observables to be calculated exactly in the linear approximation. In the case of 225Ra, we find that its EDM may be as large as 6 to 50 x 10^{-27} e.cm.

  18. El culto de Maximón en Guatemala

    OpenAIRE

    Pédron‑Colombani, Sylvie

    2009-01-01

    Este artículo se enfoca en la figura de Maximón, deidad sincrética de Guatemala, en un contexto de desplazamiento de la religión católica popular por parte de las iglesias protestantes. Esta divinidad híbrida a la cual se agregan santos católicos como Judas Iscariote o el dios maya Mam, permite la apropiación de Maximón por segmentos diferenciados de la población (tanto indígena como mestiza). Permite igualmente ser símbolo de protestas sociales enmascaradas cuando se asocia Maximón con figur...

  19. Influence of central obesity in estimating maximal oxygen uptake

    Directory of Open Access Journals (Sweden)

    Christina Grüne de Souza e Silva

    Full Text Available OBJECTIVE: To assess the influence of central obesity on the magnitude of the error of estimate of maximal oxygen uptake in maximal cycling exercise testing. METHOD: A total of 1,715 adults (68% men between 18-91 years of age underwent cardiopulmonary exercise testing using a progressive protocol to volitional fatigue. Subjects were stratified by central obesity into three quartile ranges: Q1, Q2-3 and Q4. Maximal oxygen uptake [mL.(kg.min-1] was estimated by the attained maximal workload and body weight using gender- and population-specific equations. The error of estimate [mL.(kg.min-1] and percent error between measured and estimated maximal oxygen uptake values were compared among obesity quartile ranges. RESULTS: The error of estimate and percent error differed (mean ± SD for men (Q1=1.3±3.7 and 2.0±10.4; Q2-3=0.5±3.1 and -0.5±13.0; and Q4=-0.3±2.8 and -4.5±15.8 (p<0.05 and for women (Q1=1.6±3.3 and 3.6±10.2; Q2-3=0.4±2.7 and -0.4±11.8; and Q4=-0.9±2.3 and -10.0±22.7 (p<0.05. CONCLUSION: Central obesity directly influences the magnitude of the error of estimate of maximal oxygen uptake and should be considered when direct expired gas analysis is unavailable.

  20. Greedy SINR Maximization in Collaborative Multibase Wireless Systems

    Directory of Open Access Journals (Sweden)

    Popescu Otilia

    2004-01-01

    Full Text Available We present a codeword adaptation algorithm for collaborative multibase wireless systems. The system is modeled with multiple inputs and multiple outputs (MIMO in which information is transmitted using multicode CDMA, and codewords are adapted based on greedy maximization of the signal-to-interference-plus-noise ratio. The procedure monotonically increases the sum capacity and, when repeated iteratively for all codewords in the system, converges to a fixed point. Fixed-point properties and a connection with sum capacity maximization, along with a discussion of simulations that corroborate the basic analytic results, are included in the paper.

  1. Neutrino Mass Textures from Oscillations with Maximal Mixing

    CERN Document Server

    Altarelli, Guido; Altarelli, Guido; Feruglio, Ferruccio

    1998-01-01

    We study the implications of neutrino oscillations with maximal mixing for the neutrino Dirac and Majorana matrices in the see-saw mechanism for three non degenerate neutrino masses. We find the form of the Dirac matrix for a structure-less Majorana matrix and, conversely, the structure of the Majorana matrix if the Dirac matrix is according to our naive intuition. We give some examples of Majorana matrices that, in a 3 X 3 context, lead to maximal mixing without too much fine tuning and cross talk with the Dirac input.

  2. Identities on maximal subgroups of GLn(D)

    International Nuclear Information System (INIS)

    Kiani, D.; Mahdavi-Hezavehi, M.

    2002-04-01

    Let D be a division ring with centre F. Assume that M is a maximal subgroup of GL n (D), n≥1 such that Z(M) is algebraic over F. Group identities on M and polynomial identities on the F-linear hull F[M] are investigated. It is shown that if F[M] is a PI-algebra, then [D:F] n (D) and M is a maximal subgroup of N. If M satisfies a group identity, it is shown that M is abelian-by-finite. (author)

  3. Anatomy of maximal stop mixing in the MSSM

    Energy Technology Data Exchange (ETDEWEB)

    Bruemmer, Felix [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Kraml, Sabine; Kulkarni, Suchita [CNRS/IN2P3, INPG, Grenoble (France). Laboratoire de Physique Subatomique et de Cosmologie

    2012-05-15

    A Standard Model-like Higgs near 125 GeV in the MSSM requires multi-TeV stop masses, or a near-maximal contribution to its mass from stop mixing. We investigate the maximal mixing scenario, and in particular its prospects for being realized it in potentially realistic GUT models. We work out constraints on the possible GUT-scale soft terms, which we compare with what can be obtained from some well-known mechanisms of SUSY breaking mediation. Finally, we analyze two promising scenarios in detail, namely gaugino mediation and gravity mediation with non-universal Higgs masses.

  4. On Maximal Non-Disjoint Families of Subsets

    Directory of Open Access Journals (Sweden)

    Yu. A. Zuev

    2017-01-01

    Full Text Available The paper studies maximal non-disjoint families of subsets of a finite set. Non-disjointness means that any two subsets of a family have a nonempty intersection. The maximality is expressed by the fact that adding a new subset to the family cannot increase its power without violating a non-disjointness condition. Studying the properties of such families is an important section of the extreme theory of sets. Along with purely combinatorial interest, the problems considered here play an important role in informatics, anti-noise coding, and cryptography.In 1961 this problem saw the light of day in the Erdos, Ko and Rado paper, which established a maximum power of the non-disjoint family of subsets of equal power. In 1974 the Erdos and Claytman publication estimated the number of maximal non-disjoint families of subsets without involving the equality of their power. These authors failed to establish an asymptotics of the logarithm of the number of such families when the power of a basic finite set tends to infinity. However, they suggested such an asymptotics as a hypothesis. A.D. Korshunov in two publications in 2003 and 2005 established the asymptotics for the number of non-disjoint families of the subsets of arbitrary powers without maximality condition of these families.The basis for the approach used in the paper to study the families of subsets is their description in the language of Boolean functions. A one-to-one correspondence between a family of subsets and a Boolean function is established by the fact that the characteristic vectors of subsets of a family are considered to be the unit sets of a Boolean function. The main theoretical result of the paper is that the maximal non-disjoint families are in one-to-one correspondence with the monotonic self-dual Boolean functions. When estimating the number of maximal non-disjoint families, this allowed us to use the result of A.A. Sapozhenko, who established the asymptotics of the number of the

  5. Gap processing for adaptive maximal poisson-disk sampling

    KAUST Repository

    Yan, Dongming

    2013-10-17

    In this article, we study the generation of maximal Poisson-disk sets with varying radii. First, we present a geometric analysis of gaps in such disk sets. This analysis is the basis for maximal and adaptive sampling in Euclidean space and on manifolds. Second, we propose efficient algorithms and data structures to detect gaps and update gaps when disks are inserted, deleted, moved, or when their radii are changed.We build on the concepts of regular triangulations and the power diagram. Third, we show how our analysis contributes to the state-of-the-art in surface remeshing. © 2013 ACM.

  6. Adaptive maximal poisson-disk sampling on surfaces

    KAUST Repository

    Yan, Dongming

    2012-01-01

    In this paper, we study the generation of maximal Poisson-disk sets with varying radii on surfaces. Based on the concepts of power diagram and regular triangulation, we present a geometric analysis of gaps in such disk sets on surfaces, which is the key ingredient of the adaptive maximal Poisson-disk sampling framework. Moreover, we adapt the presented sampling framework for remeshing applications. Several novel and efficient operators are developed for improving the sampling/meshing quality over the state-of-theart. © 2012 ACM.

  7. Efficient maximal Poisson-disk sampling and remeshing on surfaces

    KAUST Repository

    Guo, Jianwei

    2015-02-01

    Poisson-disk sampling is one of the fundamental research problems in computer graphics that has many applications. In this paper, we study the problem of maximal Poisson-disk sampling on mesh surfaces. We present a simple approach that generalizes the 2D maximal sampling framework to surfaces. The key observation is to use a subdivided mesh as the sampling domain for conflict checking and void detection. Our approach improves the state-of-the-art approach in efficiency, quality and the memory consumption.

  8. Moving multiple sinks through wireless sensor networks for lifetime maximization.

    Energy Technology Data Exchange (ETDEWEB)

    Petrioli, Chiara (Universita di Roma); Carosi, Alessio (Universita di Roma); Basagni, Stefano (Northeastern University); Phillips, Cynthia Ann

    2008-01-01

    Unattended sensor networks typically watch for some phenomena such as volcanic events, forest fires, pollution, or movements in animal populations. Sensors report to a collection point periodically or when they observe reportable events. When sensors are too far from the collection point to communicate directly, other sensors relay messages for them. If the collection point location is static, sensor nodes that are closer to the collection point relay far more messages than those on the periphery. Assuming all sensor nodes have roughly the same capabilities, those with high relay burden experience battery failure much faster than the rest of the network. However, since their death disconnects the live nodes from the collection point, the whole network is then dead. We consider the problem of moving a set of collectors (sinks) through a wireless sensor network to balance the energy used for relaying messages, maximizing the lifetime of the network. We show how to compute an upper bound on the lifetime for any instance using linear and integer programming. We present a centralized heuristic that produces sink movement schedules that produce network lifetimes within 1.4% of the upper bound for realistic settings. We also present a distributed heuristic that produces lifetimes at most 25:3% below the upper bound. More specifically, we formulate a linear program (LP) that is a relaxation of the scheduling problem. The variables are naturally continuous, but the LP relaxes some constraints. The LP has an exponential number of constraints, but we can satisfy them all by enforcing only a polynomial number using a separation algorithm. This separation algorithm is a p-median facility location problem, which we can solve efficiently in practice for huge instances using integer programming technology. This LP selects a set of good sensor configurations. Given the solution to the LP, we can find a feasible schedule by selecting a subset of these configurations, ordering them

  9. Emotional Control and Instructional Effectiveness: Maximizing a Timeout

    Science.gov (United States)

    Andrews, Staci R.

    2015-01-01

    This article provides recommendations for best practices for basketball coaches to maximize the instructional effectiveness of a timeout during competition. Practical applications are derived from research findings linking emotional intelligence to effective coaching behaviors. Additionally, recommendations are based on the implications of the…

  10. On the maximal dimension of a completely entangled subspace for ...

    Indian Academy of Sciences (India)

    Home; Journals; Proceedings – Mathematical Sciences; Volume 114; Issue 4. On the Maximal Dimension of a Completely ... Using the methods of elementary linear algebra and the intersection theorem for projective varieties in basic algebraic geometry we prove that. max S ∈ E dim ⁡ S = d 1 d 2 … d k − ( d 1 + ⋯ + d k ) + ...

  11. Maximal regularity for non-autonomous stochastic evolution ...

    Indian Academy of Sciences (India)

    Tôn Vi?t T?

    2017-11-17

    Nov 17, 2017 ... The abstract results are then applied to a stochastic partial differential equation. Keywords. Evolution operators; stochastic linear evolution equations; strict solutions; maximal regularity; UMD Banach spaces of type 2. 2010 Mathematics Subject Classification. Primary: 60H15, 35R60; Secondary: 47D06. 1.

  12. Transformation of bipartite non-maximally entangled states into a ...

    Indian Academy of Sciences (India)

    We present two schemes for transforming bipartite non-maximally entangled states into a W state in cavity QED system, by using highly detuned interactions and the resonant interactions between ... Proceedings of the International Workshop/Conference on Computational Condensed Matter Physics and Materials Science

  13. Extract of Zanthoxylum bungeanum maxim seed oil reduces ...

    African Journals Online (AJOL)

    Purpose: To investigate the anti-hyperlipidaemic effect of extract of Zanthoxylum bungeanum Maxim. seed oil (EZSO) on high-fat diet (HFD)-induced hyperlipidemic hamsters. Methods: Following feeding with HFD for 30 days, hyperlipidemic hamsters were intragastrically treated with EZSO for 60 days. Serum levels of ...

  14. The Boundary Crossing Theorem and the Maximal Stability Interval

    Directory of Open Access Journals (Sweden)

    Jorge-Antonio López-Renteria

    2011-01-01

    useful tools in the study of the stability of family of polynomials. Although both of these theorem seem intuitively obvious, they can be used for proving important results. In this paper, we give generalizations of these two theorems and we apply such generalizations for finding the maximal stability interval.

  15. A decision theoretic framework for profit maximization in direct marketing

    NARCIS (Netherlands)

    Muus, L.; van der Scheer, H.; Wansbeek, T.J.; Montgomery, A.; Franses, P.H.B.F.

    2002-01-01

    One of the most important issues facing a firm involved in direct marketing is the selection of addresses from a mailing list. When the parameters of the model describing consumers' reaction to a mailing are known, addresses for a future mailing can be selected in a profit-maximizing way. Usually,

  16. Improved endpoint bounds for the lacunary spherical maximal operator

    OpenAIRE

    Cladek, Laura; Krause, Ben

    2017-01-01

    We prove new endpoint bounds for the lacunary spherical maximal operator and as a consequence obtain almost everywhere pointwise convergence of lacunary spherical means for functions locally in $L\\log\\log\\log L(\\log\\log\\log\\log L)^{1+\\epsilon}$ for any $\\epsilon>0$.

  17. Maximal multiplier operators in Lp(·)(Rn) spaces

    Czech Academy of Sciences Publication Activity Database

    Gogatishvili, Amiran; Kopaliani, T.

    2016-01-01

    Roč. 140, č. 4 (2016), s. 86-97 ISSN 0007-4497 R&D Projects: GA ČR GA13-14743S Institutional support: RVO:67985840 Keywords : spherical maximal function * variable Lebesque spaces * boundedness result Subject RIV: BA - General Mathematics Impact factor: 0.750, year: 2016 http://www.sciencedirect.com/science/article/pii/S0007449715000329

  18. Submaximal exercise capacity and maximal power output in polio subjects

    NARCIS (Netherlands)

    Nollet, F.; Beelen, A.; Sargeant, A. J.; de Visser, M.; Lankhorst, G. J.; de Jong, B. A.

    2001-01-01

    OBJECTIVES: To compare the submaximal exercise capacity of polio subjects with postpoliomyelitis syndrome (PPS) and without (non-PPS) with that of healthy control subjects, to investigate the relationship of this capacity with maximal short-term power and quadriceps strength, and to evaluate

  19. Maximal regularity for non-autonomous stochastic evolution ...

    Indian Academy of Sciences (India)

    A non-autonomous stochastic linear evolution equation in UMD Banach spaces of type 2 is considered. We construct unique strict solutions to the equation and show their maximal regularity. The abstract results are then applied to a stochastic partial differential equation.

  20. Larvicidal Activity of Isodon japonicus var. glaucocalyx (Maxim ...

    African Journals Online (AJOL)

    HP

    Purpose: To determine the larvicidal activity of the essential oil derived from Isodon japonicus var. glaucocalyx (Maxim.) H.W.Li (Labiatae) aerial parts at flowering stage against the larvae of Aedes aegypti L. Methods: The essential oil of I. japonicus var. glaucocalyx aerial parts was obtained by hydrodistillation.

  1. Transformation of bipartite non-maximally entangled states into a ...

    Indian Academy of Sciences (India)

    [6], quantum cryptography [7] and so on. The preparation of entangled state becomes more and more important in quantum infor- mation processing. One knows that bipartite entanglement can be generated through a variety of solutions [8–10]. A maximally entangled state of two qubits is called a Bell state. For atomic qubits ...

  2. Prediction of maximal heart rate: comparison using a novel and ...

    African Journals Online (AJOL)

    Prediction of maximal heart rate: comparison using a novel and conventional equation. LR Keytel, E Mukwevho, MA Will, M Lambert. Abstract. No Abstract. African Journal for Physical, Health Education, Recreation and Dance Vol. 11(3) 2005: 269-277. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL ...

  3. Impact of training status on maximal oxygen uptake criteria ...

    African Journals Online (AJOL)

    Only 11% of the trained and 56% of the untrained individuals achieved a plateau in the oxygen uptake curve. Peak treadmill running speed was significantly faster and total test time significantly longer in the trained group. In contrast, peak lactate, although maximal for both groups, was significantly higher in the untrained ...

  4. Quantum state space as a maximal consistent set

    Science.gov (United States)

    Tabia, Gelo Noel

    2012-02-01

    Measurement statistics in quantum theory are obtained from the Born rule and the uniqueness of the probability measure it assigns through quantum states is guaranteed by Gleason's theorem. Thus, a possible systematic way of exploring the geometry of quantum state space expresses quantum states in terms of outcome probabilities of a symmetric informationally complete measurement. This specific choice for representing quantum states is motivated by how the associated probability space provides a natural venue for characterizing the set of quantum states as a geometric construct called a maximal consistent set. We define the conditions for consistency and maximality of a set, provide some examples of maximal consistent sets and attempt to deduce the steps for building up a maximal consistent set of probability distributions equivalent to Hilbert space. In particular, we demonstrate how the reconstruction procedure works for qutrits and observe how it reveals an elegant underlying symmetry among five SIC-POVMs and a complete set of mutually unbiased bases, known in finite affine geometry as the Hesse configuration.

  5. An optimal thermal condition for maximal chlorophyll extraction

    Directory of Open Access Journals (Sweden)

    Fu Jia-Jia

    2017-01-01

    Full Text Available This work describes an environmentally friendly process for chlorophyll extraction from bamboo leaves. Shaking water bath and ultrasound cleaner are adopted in this technology, and the influence of temperature of the water bath and ultrasonic cleaner is evaluated. Results indicated that there is an optimal condition for maximal yield of chlorophyll.

  6. Principle of Entropy Maximization for Nonequilibrium Steady States

    DEFF Research Database (Denmark)

    Shapiro, Alexander; Stenby, Erling Halfdan

    2002-01-01

    The goal of this contribution is to find out to what extent the principle of entropy maximization, which serves as a basis for the equilibrium thermodynamics, may be generalized onto non-equilibrium steady states. We prove a theorem that, in the system of thermodynamic coordinates, where entropy...

  7. An application of the maximal independent set algorithm to course ...

    African Journals Online (AJOL)

    In this paper, we demonstrated one of the many applications of the Maximal Independent Set Algorithm in the area of course allocation. A program was developed in Pascal and used in implementing a modified version of the algorithm to assign teaching courses to available lecturers in any academic environment and it ...

  8. Maximal Regularity of the Discrete Harmonic Oscillator Equation

    Directory of Open Access Journals (Sweden)

    Airton Castro

    2009-01-01

    Full Text Available We give a representation of the solution for the best approximation of the harmonic oscillator equation formulated in a general Banach space setting, and a characterization of lp-maximal regularity—or well posedness—solely in terms of R-boundedness properties of the resolvent operator involved in the equation.

  9. Applications of expectation maximization algorithm for coherent optical communication

    DEFF Research Database (Denmark)

    Carvalho, L.; Oliveira, J.; Zibar, Darko

    2014-01-01

    In this invited paper, we present powerful statistical signal processing methods, used by machine learning community, and link them to current problems in optical communication. In particular, we will look into iterative maximum likelihood parameter estimation based on expectation maximization al...

  10. Simplicity and maximal commutative subalgebras of twisted generalized Weyl algebras

    DEFF Research Database (Denmark)

    Hartwig, J.T.; Öinert, Per Johan

    2013-01-01

    conditions for certain TGWAs to be simple, in the case when R is commutative. We illustrate our theorems by considering some special classes of TGWAs and providing concrete examples. We also discuss how simplicity of a TGWA is related to the maximal commutativity of R and the (non-)existence of non...

  11. Should I Stay or Should I Go? Maximizers versus Satisficers

    Science.gov (United States)

    Buri, John R.; Gunty, Amy; King, Stephanie L.

    2008-01-01

    In the present study, university students were presented a scenario in which a married couple was struggling in their marriage. These students were asked how likely it is that they would stay in a difficult marriage like the one described in the scenario. Each student also completed Schwartz's (2004) Maximization Scale. High scorers on this scale…

  12. Maximizing plant density affects broccoli yield and quality

    Science.gov (United States)

    Increased demand for fresh market bunch broccoli (Brassica oleracea L. var. italica) has led to increased production along the United States east coast. Maximizing broccoli yields is a primary concern for quickly expanding southeastern commercial markets. This broccoli plant density study was carr...

  13. Maximal saddle solution of a nonlinear elliptic equation involving the ...

    Indian Academy of Sciences (India)

    College of Mathematics and Econometrics, Hunan University, Changsha 410082, China. E-mail: huahuiyan@163.com; duzr@hnu.edu.cn. MS received 3 September 2012; revised 20 December 2012. Abstract. A saddle solution is called maximal saddle solution if its absolute value is not smaller than those absolute values ...

  14. Building the case for biofortification: measuring and maximizing ...

    African Journals Online (AJOL)

    Building the case for biofortification: measuring and maximizing impact in the HarvestPlus program. N Johnson, D Asare-Marfo, M Zeller, E Birol. Abstract. This paper describes the research and related activities that HarvestPlus undertook at each stage of the research process—discovery, proof of concept, delivery at ...

  15. Quantitative approaches for profit maximization in direct marketing

    NARCIS (Netherlands)

    van der Scheer, H.R.

    1998-01-01

    An effective direct marketing campaign aims at selecting those targets, offer and communication elements - at the right time - that maximize the net profits. The list of individuals to be mailed, i.e. the targets, is considered to be the most important component. Therefore, a large amount of direct

  16. Limits to maximal performance in individuals with spinal cord injury.

    Science.gov (United States)

    Hopman, M T; Dueck, C; Monroe, M; Philips, W T; Skinner, J S

    1998-02-01

    The purpose of this study was to examine the effect of four conditions that might improve oxygen transport and/or utilization during maximal exercise performance in individuals with spinal cord injury (SCI). Five males with tetraplegia (TP) and four males with paraplegia (PR) performed maximal arm cranking exercise in the following positions: 1) sitting; 2) supine; and 3) sitting with the addition of a) anti-gravity suit (anit-G), b) elastic stockings and abdominal binder, and c) functional electrical stimulation (FES) of the paralysed leg muscles. Peak power output (PO peak), peak oxygen uptake (VO2peak), peak heart rate (HR peak) and maximal systolic blood pressure were significantly lower in TP compared to PR for all conditions. A significant decrease in HR peak for PR, and a significant increase in VO2peak/kg for TP was seen during the supine compared to sitting condition. Respiratory exchange ratio (R) decreased significantly during the FES compared to the sitting condition in TP. No other changes were observed for any of the other conditions in either group. Improvements in central circulation previously reported during submaximal exercise for these four conditions did not result in a concomitant rise in maximal exercise performance. The results of this study suggest that the limitation in VO2peak for individuals with SCI is located peripherally (small active muscle mass) rather than centrally (heart or lungs).

  17. Maximizing vegetation response on management burns by identifying fire regimes

    Science.gov (United States)

    V. Thomas Parker

    1989-01-01

    Maintenance of vegetation is a central goal of watershed management. When prescribed burning of chaparral is included in management practice, then it is important for managers to understand and use the natural chaparral fire regime to maximize vegetation response. Variations from the natural fire regime in intensity, frequency, season, and environmental conditions at...

  18. Painting new lines : Maximizing color difference in metro maps

    NARCIS (Netherlands)

    Griffioen, Simone; Kiselev, Arthemy

    2015-01-01

    Each metro line usually has its own color on the map. For obvious reasons, these colors should be maximally different. Suppose a new metro line is built. We now explain a strategy to choose the color or several colors for the new lines, making them as different as possible from both the old ones and

  19. Maximal Sharing in the Lambda Calculus with Letrec

    NARCIS (Netherlands)

    Grabmayer, C.A.; Rochel, J.

    2014-01-01

    Increasing sharing in programs is desirable to compactify the code, and to avoid duplication of reduction work at run-time, thereby speeding up execution. We show how a maximal degree of sharing can be obtained for programs expressed as terms in the lambda calculus with letrec. We introduce a notion

  20. Distortion of maximal elevator activity by unilateral premature tooth contact

    DEFF Research Database (Denmark)

    Bakke, Merete; Møller, Eigild

    1980-01-01

    In four subjects the electrical activity in the anterior and posterior temporal and masseter muscles during maximal bite was recorded bilaterally with and without premature unilateral contact. Muscle activity was measured as the average level and the peak of the mean voltage with layers of strips...

  1. Assessment of maximal handgrip strength : How many attempts are needed?

    NARCIS (Netherlands)

    Reijnierse, Esmee M.; de Jong, Nynke; Trappenburg, Marijke C.; Blauw, Gerard Jan; Butler-Browne, Gillian; Gapeyeva, Helena; Hogrel, Jean Yves; Mcphee, Jamie S.; Narici, Marco V.; Sipilä, Sarianna; Stenroth, Lauri; van Lummel, Rob C.; Pijnappels, Mirjam; Meskers, Carel G M; Maier, Andrea B.

    Background: Handgrip strength (HGS) is used to identify individuals with low muscle strength (dynapenia). The influence of the number of attempts on maximal HGS is not yet known and may differ depending on age and health status. This study aimed to assess how many attempts of HGS are required to

  2. Suppression of maximal linear gluon polarization in angular asymmetries

    NARCIS (Netherlands)

    Boer, Daniel; Mulders, Piet J.; Zhou, Jian; Zhou, Ya-jin

    2017-01-01

    We perform a phenomenological analysis of the cos 2 phi azimuthal asymmetry in virtual photon plus jet production induced by the linear polarization of gluons in unpolarized pA collisions. Although the linearly polarized gluon distribution becomes maximal at small x, TMD evolution leads to a Sudakov

  3. Multi-start approach for an integer determinant maximization problem

    NARCIS (Netherlands)

    Sotirov, R.; Terlaky, T.

    2013-01-01

    In this article, we present a multi-start approach to solve a determinant maximization problem of an integer matrix variable that has a constant trace. In order to enforce that elements of the matrix variable are integer, we add a nonlinear repeller term to the objective function. To solve this

  4. Mentoring as Professional Development for Novice Entrepreneurs: Maximizing the Learning

    Science.gov (United States)

    St-Jean, Etienne

    2012-01-01

    Mentoring can be seen as relevant if not essential in the continuing professional development of entrepreneurs. In the present study, we seek to understand how to maximize the learning that occurs through the mentoring process. To achieve this, we consider various elements that the literature suggested are associated with successful mentoring and…

  5. A Revenue Maximization Approach for Provisioning Services in Clouds

    Directory of Open Access Journals (Sweden)

    Li Pan

    2015-01-01

    Full Text Available With the increased reliability, security, and reduced cost of cloud services, more and more users are attracted to having their jobs and applications outsourced into IAAS data centers. For a cloud provider, deciding how to provision services to clients is far from trivial. The objective of this decision is maximizing the provider’s revenue, while fulfilling its IAAS resource constraints. The above problem is defined as IAAS cloud provider revenue maximization (ICPRM problem in this paper. We formulate a service provision approach to help a cloud provider to determine which combination of clients to admit and in what Quality-of-Service (QoS levels and to maximize provider’s revenue given its available resources. We show that the overall problem is a nondeterministic polynomial- (NP- hard one and develop metaheuristic solutions based on the genetic algorithm to achieve revenue maximization. The experimental simulations and numerical results show that the proposed approach is both effective and efficient in solving ICPRM problems.

  6. Evaluation of Epimedium brevicornum Maxim extract for anti ...

    African Journals Online (AJOL)

    Purpose: To evaluate the therapeutic effect of Epimedium brevicornum Maxim. extract (EBME) on ovariectomy-induced osteoporosis in rats. Methods: The rats were divided into six experimental groups, viz, control (group 1) and five ovariectomy-induced (OVX) groups. The OVX groups include OVX-inducing agent only ...

  7. Prediction equations for maximal respiratory pressures of Brazilian adolescents

    Directory of Open Access Journals (Sweden)

    Raquel E. F. Mendes

    2013-06-01

    Full Text Available BACKGROUND: The literature emphasizes the need for studies to provide reference values and equations able to predict respiratory muscle strength of Brazilian subjects at different ages and from different regions of Brazil. OBJECTIVES: To develop prediction equations for maximal respiratory pressures (MRP of Brazilian adolescents. METHOD: In total, 182 healthy adolescents (98 boys and 84 girls aged between 12 and 18 years, enrolled in public and private schools in the city of Natal-RN, were evaluated using an MVD300 digital manometer (Globalmed® according to a standardized protocol. Statistical analysis was performed using SPSS Statistics 17.0 software, with a significance level of 5%. Data normality was verified using the Kolmogorov-Smirnov test, and descriptive analysis results were expressed as the mean and standard deviation. To verify the correlation between the MRP and the independent variables (age, weight, height and sex, the Pearson correlation test was used. To obtain the prediction equations, stepwise multiple linear regression was used. RESULTS: The variables height, weight and sex were correlated to MRP. However, weight and sex explained part of the variability of MRP, and the regression analysis in this study indicated that these variables contributed significantly in predicting maximal inspiratory pressure, and only sex contributed significantly to maximal expiratory pressure. CONCLUSION: This study provides reference values and two models of prediction equations for maximal inspiratory and expiratory pressures and sets the necessary normal lower limits for the assessment of the respiratory muscle strength of Brazilian adolescents.

  8. Extract of Zanthoxylum bungeanum Maxim Seed Oil Reduces ...

    African Journals Online (AJOL)

    Abstract. Purpose: To investigate the anti-hyperlipidaemic effect of extract of Zanthoxylum bungeanum Maxim. ... Further researches in human and animal are both .... tissues. In Western blot assay, the PPAR protein was. ・ significantly increased by approximately 120 % in the liver tissues of the HPL group compared with.

  9. Maximizing the model for Discounted Stream of Utility from ...

    African Journals Online (AJOL)

    Osagiede et al. (2009) considered an analytic model for maximizing discounted stream of utility from consumption when the rate of production is linear. A solution was provided to a level where methods of solving order differential equations will be applied, but they left off there, as a result of the mathematical complexity ...

  10. Maximal near-field radiative heat transfer between two plates

    Science.gov (United States)

    Nefzaoui, Elyes; Ezzahri, Younès; Drévillon, Jérémie; Joulain, Karl

    2013-09-01

    Near-field radiative transfer is a promising way to significantly and simultaneously enhance both thermo-photovoltaic (TPV) devices power densities and efficiencies. A parametric study of Drude and Lorentz models performances in maximizing near-field radiative heat transfer between two semi-infinite planes separated by nanometric distances at room temperature is presented in this paper. Optimal parameters of these models that provide optical properties maximizing the radiative heat flux are reported and compared to real materials usually considered in similar studies, silicon carbide and heavily doped silicon in this case. Results are obtained by exact and approximate (in the extreme near-field regime and the electrostatic limit hypothesis) calculations. The two methods are compared in terms of accuracy and CPU resources consumption. Their differences are explained according to a mesoscopic description of nearfield radiative heat transfer. Finally, the frequently assumed hypothesis which states a maximal radiative heat transfer when the two semi-infinite planes are of identical materials is numerically confirmed. Its subsequent practical constraints are then discussed. Presented results enlighten relevant paths to follow in order to choose or design materials maximizing nano-TPV devices performances.

  11. Cooling the vertical surface by conditionally single pulses

    Directory of Open Access Journals (Sweden)

    Karpov Pavel

    2017-01-01

    Full Text Available You Sprays with periodic supply of the droplet phase have great opportunities to control the heat exchange processes. Varying pulse duration and frequency of their repetition, we can achieve the optimal conditions of evaporative cooling with minimization of the liquid flow rate. The paper presents experimental data on studying local heat transfer on a large subcooled surface, obtained on the original setup with multinozzle controlled system of impact irrigation by the gas-droplet flow. A contribution to intensification of the spray parameters (flow rate, pulse duration, repetition frequency per a growth of integral heat transfer was studied. Data on instantaneous distribution of the heat flux value helped us to describe the processes occurring on the studied surface. These data could describe the regime of “island” film cooling.

  12. Cooling the vertical surface by conditionally single pulses

    Science.gov (United States)

    Karpov, Pavel; Nazarov, Alexander; Serov, Anatoly; Terekhov, Victor

    2017-10-01

    You Sprays with periodic supply of the droplet phase have great opportunities to control the heat exchange processes. Varying pulse duration and frequency of their repetition, we can achieve the optimal conditions of evaporative cooling with minimization of the liquid flow rate. The paper presents experimental data on studying local heat transfer on a large subcooled surface, obtained on the original setup with multinozzle controlled system of impact irrigation by the gas-droplet flow. A contribution to intensification of the spray parameters (flow rate, pulse duration, repetition frequency) per a growth of integral heat transfer was studied. Data on instantaneous distribution of the heat flux value helped us to describe the processes occurring on the studied surface. These data could describe the regime of "island" film cooling.

  13. Trichloroethylene (TCE) removal in a single pulse suspension bioreactor

    Czech Academy of Sciences Publication Activity Database

    Volčík, V.; Hoffmann, J.; Růžička, J.; Sergejevova, Magda

    2005-01-01

    Roč. 74, - (2005), s. 293-304 ISSN 0301-4797 R&D Projects: GA MŠk LN00A141 Institutional research plan: CEZ:AV0Z50200510 Keywords : trichlorethylene * phenol * cometabolism Subject RIV: EE - Microbiology, Virology Impact factor: 1.163, year: 2005

  14. MAXIMIZING SOCIAL VALUE IN THE HOTEL ONLINE ENVIRONMENT USING AN ANALYTIC HIERARCHY PROCESS

    Directory of Open Access Journals (Sweden)

    Carmen Păunescu

    2018-03-01

    Full Text Available The paper analyses the possibilities that hoteliers have to create and maximize the social value of their online platforms, in terms of their functionality and usage, in order to improve sales and increase hotels’ performance. It also discusses the opportunities that hotel managers can take to improve the hotel online decision-making strategy to convert more effectively visitors into actual customers. Although social value creation of online platforms has been well researched in the specialized literature, recent research has not examined the ways the online social value can be maximized and put into effective commercial use. The paper reviews the dimensions and characteristics of the hotel online environment by integrating literature analysis and field research practices. It employs the analytic hierarchy process method to analyse key elements of the hotel online environment that can serve as a focal point for value creation. The literature review and field research conducted pinpoint three possibilities of creating online social value: (a building online trust, (b ensuring high quality of the online service, and (c providing effective online communication experience. The paper results have given deeper understanding regarding potential areas of the hotel online environment where social value can be obtained. They prove applicability of the analytic hierarchy process method for evaluation and selection of strategies for online social value creation. At the same time, the paper provides new valuable insights to hoteliers, which might support their decisions to improve the business by proactively incorporating strategies for online social value maximization.

  15. Maximizing Kolmogorov Complexity for accurate and robust bright field cell segmentation.

    Science.gov (United States)

    Mohamadlou, Hamid; Shope, Joseph C; Flann, Nicholas S

    2014-01-30

    Analysis of cellular processes with microscopic bright field defocused imaging has the advantage of low phototoxicity and minimal sample preparation. However bright field images lack the contrast and nuclei reporting available with florescent approaches and therefore present a challenge to methods that segment and track the live cells. Moreover, such methods must be robust to systemic and random noise, variability in experimental configuration, and the multiple unknowns in the biological system under study. A new method called maximal-information is introduced that applies a non-parametric information theoretic approach to segment bright field defocused images. The method utilizes a combinatorial optimization strategy to select specific defocused images from each image stack such that set complexity, a Kolmogorov complexity measure, is maximized. Differences among these selected images are then applied to initialize and guide a level set based segmentation algorithm. The performance of the method is compared with a recent approach that uses a fixed defocused image selection strategy over an image data set of embryonic kidney cells (HEK 293T) from multiple experiments. Results demonstrate that the adaptive maximal-information approach significantly improves precision and recall of segmentation over the diversity of data sets. Integrating combinatorial optimization with non-parametric Kolmogorov complexity has been shown to be effective in extracting information from microscopic bright field defocused images. The approach is application independent and has the potential to be effective in processing a diversity of noisy and redundant high throughput biological data.

  16. Dual Competing Photovoltaic Supply Chains: A Social Welfare Maximization Perspective

    Science.gov (United States)

    Su, Shong-Iee Ivan

    2017-01-01

    In the past decades, the inappropriate subsidy policies in many nations have caused problems such as serious oversupply, fierce competition and subpar social welfare in the photovoltaic (PV) industry in many nations. There is a clear shortage in the PV industry literature regarding how dual supply chains compete and the key decision issues regarding the competition between dual PV supply chains. It is critical to develop effective subsidy policies for the competing PV supply chains to achieve social welfare maximization. This study has explored the dual PV supply chain competition under the Bertrand competition assumption by three game-theoretical modeling scenarios (or supply chain strategies) considering either the public subsidy or no subsidy from a social welfare maximization perspective. A numerical analysis complemented by two sensitivity analyses provides a better understanding of the pricing and quantity decision dynamics in the dual supply chains under three different supply chain strategies and the corresponding outcomes regarding the total supply chain profits, the social welfare and the required total subsidies. The key findings disclose that if there are public subsidies, the dual PV supply chains have the strongest intention to pursue the decentralized strategy to achieve their maximal returns rather than the centralized strategy that would achieve the maximal social welfare; however, the government would need to pay for the maximal subsidy budget. Thus, the best option for the government would be to encourage the dual PV supply chains to adopt a centralized strategy since this will not only maximize the social welfare but also, at the same time, minimize the public subsidy. With a smart subsidy policy, the PV industry can make the best use of the subsidy budget and grow in a sustainable way to support the highly demanded solar power generation in many countries trying very hard to increase the proportion of their clean energy to combat the global

  17. Dual Competing Photovoltaic Supply Chains: A Social Welfare Maximization Perspective.

    Science.gov (United States)

    Chen, Zhisong; Su, Shong-Iee Ivan

    2017-11-20

    In the past decades, the inappropriate subsidy policies in many nations have caused problems such as serious oversupply, fierce competition and subpar social welfare in the photovoltaic (PV) industry in many nations. There is a clear shortage in the PV industry literature regarding how dual supply chains compete and the key decision issues regarding the competition between dual PV supply chains. It is critical to develop effective subsidy policies for the competing PV supply chains to achieve social welfare maximization. This study has explored the dual PV supply chain competition under the Bertrand competition assumption by three game-theoretical modeling scenarios (or supply chain strategies) considering either the public subsidy or no subsidy from a social welfare maximization perspective. A numerical analysis complemented by two sensitivity analyses provides a better understanding of the pricing and quantity decision dynamics in the dual supply chains under three different supply chain strategies and the corresponding outcomes regarding the total supply chain profits, the social welfare and the required total subsidies. The key findings disclose that if there are public subsidies, the dual PV supply chains have the strongest intention to pursue the decentralized strategy to achieve their maximal returns rather than the centralized strategy that would achieve the maximal social welfare; however, the government would need to pay for the maximal subsidy budget. Thus, the best option for the government would be to encourage the dual PV supply chains to adopt a centralized strategy since this will not only maximize the social welfare but also, at the same time, minimize the public subsidy. With a smart subsidy policy, the PV industry can make the best use of the subsidy budget and grow in a sustainable way to support the highly demanded solar power generation in many countries trying very hard to increase the proportion of their clean energy to combat the global

  18. Dual Competing Photovoltaic Supply Chains: A Social Welfare Maximization Perspective

    Directory of Open Access Journals (Sweden)

    Zhisong Chen

    2017-11-01

    Full Text Available In the past decades, the inappropriate subsidy policies in many nations have caused problems such as serious oversupply, fierce competition and subpar social welfare in the photovoltaic (PV industry in many nations. There is a clear shortage in the PV industry literature regarding how dual supply chains compete and the key decision issues regarding the competition between dual PV supply chains. It is critical to develop effective subsidy policies for the competing PV supply chains to achieve social welfare maximization. This study has explored the dual PV supply chain competition under the Bertrand competition assumption by three game-theoretical modeling scenarios (or supply chain strategies considering either the public subsidy or no subsidy from a social welfare maximization perspective. A numerical analysis complemented by two sensitivity analyses provides a better understanding of the pricing and quantity decision dynamics in the dual supply chains under three different supply chain strategies and the corresponding outcomes regarding the total supply chain profits, the social welfare and the required total subsidies. The key findings disclose that if there are public subsidies, the dual PV supply chains have the strongest intention to pursue the decentralized strategy to achieve their maximal returns rather than the centralized strategy that would achieve the maximal social welfare; however, the government would need to pay for the maximal subsidy budget. Thus, the best option for the government would be to encourage the dual PV supply chains to adopt a centralized strategy since this will not only maximize the social welfare but also, at the same time, minimize the public subsidy. With a smart subsidy policy, the PV industry can make the best use of the subsidy budget and grow in a sustainable way to support the highly demanded solar power generation in many countries trying very hard to increase the proportion of their clean energy to

  19. Comparison of changes in the mobility of the pelvic floor muscle on during the abdominal drawing-in maneuver, maximal expiration, and pelvic floor muscle maximal contraction

    OpenAIRE

    Jung, Halim; Jung, Sangwoo; Joo, Sunghee; Song, Changho

    2016-01-01

    [Purpose] The purpose of this study was to compare changes in the mobility of the pelvic floor muscle during the abdominal drawing-in maneuver, maximal expiration, and pelvic floor muscle maximal contraction. [Subjects] Thirty healthy adults participated in this study (15 men and 15 women). [Methods] All participants performed a bridge exercise and abdominal curl-up during the abdominal drawing-in maneuver, maximal expiration, and pelvic floor muscle maximal contraction. Pelvic floor mobility...

  20. On the maximal noise for stochastic and QCD travelling waves

    International Nuclear Information System (INIS)

    Peschanski, Robi

    2008-01-01

    Using the relation of a set of nonlinear Langevin equations to reaction-diffusion processes, we note the existence of a maximal strength of the noise for the stochastic travelling wave solutions of these equations. Its determination is obtained using the field-theoretical analysis of branching-annihilation random walks near the directed percolation transition. We study its consequence for the stochastic Fisher-Kolmogorov-Petrovsky-Piscounov equation. For the related Langevin equation modeling the quantum chromodynamic nonlinear evolution of gluon density with rapidity, the physical maximal-noise limit may appear before the directed percolation transition, due to a shift in the travelling-wave speed. In this regime, an exact solution is known from a coalescence process. Universality and other open problems and applications are discussed in the outlook

  1. Bicarbonate attenuates arterial desaturation during maximal exercise in humans

    DEFF Research Database (Denmark)

    Nielsen, Henning B; Bredmose, Per P; Strømstad, Morten

    2002-01-01

    The contribution of pH to exercise-induced arterial O2 desaturation was evaluated by intravenous infusion of sodium bicarbonate (Bic, 1 M; 200-350 ml) or an equal volume of saline (Sal; 1 M) at a constant infusion rate during a "2,000-m" maximal ergometer row in five male oarsmen. Blood-gas varia......The contribution of pH to exercise-induced arterial O2 desaturation was evaluated by intravenous infusion of sodium bicarbonate (Bic, 1 M; 200-350 ml) or an equal volume of saline (Sal; 1 M) at a constant infusion rate during a "2,000-m" maximal ergometer row in five male oarsmen. Blood...

  2. Muscle mitochondrial capacity exceeds maximal oxygen delivery in humans

    DEFF Research Database (Denmark)

    Boushel, Robert Christopher; Gnaiger, Erich; Calbet, Jose A L

    2011-01-01

    Across a wide range of species and body mass a close matching exists between maximal conductive oxygen delivery and mitochondrial respiratory rate. In this study we investigated in humans how closely in-vivo maximal oxygen consumption (VO(2) max) is matched to state 3 muscle mitochondrial...... O(2) kg(-1) min(-1), exceeding the in-vivo leg VO(2) max (5.0±0.2 mmol O(2) kg(-1) min(-1)) during leg cycling with 20 kg muscle (P...... respiration. High resolution respirometry was used to quantify mitochondrial respiration from the biopsies of arm and leg muscles while in-vivo arm and leg VO(2) were determined by the Fick method during leg cycling and arm cranking. We hypothesized that muscle mitochondrial respiratory rate exceeds...

  3. LOAD THAT MAXIMIZES POWER OUTPUT IN COUNTERMOVEMENT JUMP

    Directory of Open Access Journals (Sweden)

    Pedro Jimenez-Reyes

    2016-02-01

    Full Text Available ABSTRACT Introduction: One of the main problems faced by strength and conditioning coaches is the issue of how to objectively quantify and monitor the actual training load undertaken by athletes in order to maximize performance. It is well known that performance of explosive sports activities is largely determined by mechanical power. Objective: This study analysed the height at which maximal power output is generated and the corresponding load with which is achieved in a group of male-trained track and field athletes in the test of countermovement jump (CMJ with extra loads (CMJEL. Methods: Fifty national level male athletes in sprinting and jumping performed a CMJ test with increasing loads up to a height of 16 cm. The relative load that maximized the mechanical power output (Pmax was determined using a force platform and lineal encoder synchronization and estimating the power by peak power, average power and flight time in CMJ. Results: The load at which the power output no longer existed was at a height of 19.9 ± 2.35, referring to a 99.1 ± 1% of the maximum power output. The load that maximizes power output in all cases has been the load with which an athlete jump a height of approximately 20 cm. Conclusion: These results highlight the importance of considering the height achieved in CMJ with extra load instead of power because maximum power is always attained with the same height. We advise for the preferential use of the height achieved in CMJEL test, since it seems to be a valid indicative of an individual's actual neuromuscular potential providing a valid information for coaches and trainers when assessing the performance status of our athletes and to quantify and monitor training loads, measuring only the height of the jump in the exercise of CMJEL.

  4. Oncoplastic Breast Reduction: Maximizing Aesthetics and Surgical Margins

    Directory of Open Access Journals (Sweden)

    Michelle Milee Chang

    2012-01-01

    Full Text Available Oncoplastic breast reduction combines oncologically sound concepts of cancer removal with aesthetically maximized approaches for breast reduction. Numerous incision patterns and types of pedicles can be used for purposes of oncoplastic reduction, each tailored for size and location of tumor. A team approach between reconstructive and breast surgeons produces positive long-term oncologic results as well as satisfactory cosmetic and functional outcomes, rendering oncoplastic breast reduction a favorable treatment option for certain patients with breast cancer.

  5. Oncoplastic Breast Reduction: Maximizing Aesthetics and Surgical Margins

    Science.gov (United States)

    Chang, Michelle Milee; Huston, Tara; Ascherman, Jeffrey; Rohde, Christine

    2012-01-01

    Oncoplastic breast reduction combines oncologically sound concepts of cancer removal with aesthetically maximized approaches for breast reduction. Numerous incision patterns and types of pedicles can be used for purposes of oncoplastic reduction, each tailored for size and location of tumor. A team approach between reconstructive and breast surgeons produces positive long-term oncologic results as well as satisfactory cosmetic and functional outcomes, rendering oncoplastic breast reduction a favorable treatment option for certain patients with breast cancer. PMID:23209890

  6. Local Hardy-Littlewood maximal operator in variable Lebesgue spaces

    Czech Academy of Sciences Publication Activity Database

    Gogatishvili, Amiran; Danelia, A.; Kopaliani, T.

    2014-01-01

    Roč. 8, č. 2 (2014), s. 229-244 ISSN 1735-8787 R&D Projects: GA ČR GA13-14743S Institutional support: RVO:67985840 Keywords : variable exponent Lebesgue space * local Hardy-Littlewood maximal function * local Muckenhoupt classes Subject RIV: BA - General Mathematics Impact factor: 1.050, year: 2014 http://projecteuclid.org/euclid.bjma/1396640066

  7. Resting and maximal heart rates in ectothermic vertebrates.

    Science.gov (United States)

    Lillywhite, H B; Zippel, K C; Farrell, A P

    1999-12-01

    Resting and maximal heart rates (HR) in ectothermic vertebrates are generally lower than those in endotherms and vary by more than an order of magnitude interspecifically. Variation of HR transcends phylogeny and is influenced by numerous factors including temperature, activity, gas exchange, intracardiac shunts, pH, posture, and reflexogenic regulation of blood pressure. The characteristic resting HR is rarely the intrinsic rate of the pacemaker, which is primarily modulated by cholinergic inhibition and adrenergic excitation in most species. Neuropeptides also appear to be involved in cardiac regulation, although their role is not well understood. The principal determinants of resting HR include temperature, metabolic rate and hemodynamic requirements. Maximal HRs generally do not exceed 120 b min-1, but notable exceptions include the heterothermic tuna and small reptiles having HRs in excess of 300 b min-1 at higher body temperatures. Temperature affects the intrinsic pacemaker rate as well as the relative influence of adrenergic and cholinergic modulation. It also influences the evolved capability to increase HR, with maximal cardiac responses matched to preferred body temperatures in some species. Additional factors either facilitate or limit the maximal level of HR, including: (1) characteristics of the pacemaker potential; (2) development of sarcoplasmic reticulum as a calcium store in excitation-contraction coupling; (3) low-resistance coupling of myocardial cells; (4) limitations of force development imposed by rate changes; (5) efficacy of sympathetic modulation; and (6) development of coronary circulation to enhance oxygen delivery to myocardium. In evolutionary terms, both hemodynamic and oxygen requirements appear to have been key selection pressures for rapid cardiac rates.

  8. Networks maximizing the consensus time of voter models

    Science.gov (United States)

    Iwamasa, Yuni; Masuda, Naoki

    2014-07-01

    We explore the networks that yield the largest mean consensus time of voter models under different update rules. By analytical and numerical means, we show that the so-called lollipop graph, barbell graph, and double-star graph maximize the mean consensus time under the update rules called the link dynamics, voter model, and invasion process, respectively. For each update rule, the largest mean consensus time scales as O (N3), where N is the number of nodes in the network.

  9. Maximal reductions in the Baker-Hausdorff formula

    International Nuclear Information System (INIS)

    Kolsrud, M.

    1992-05-01

    A preliminary expression for the Baker-Hausdorff formula is found up to ninth order, i.e. a series expansion of z in terms of multiple commutators, where e x =e x e y with x and y non-commuting, up to ninth degree in x,y. By means of complete sets of linear relations between multiple commutators, maximal reduction of the number of different multiple commutators in the series is obtained. 4 refs

  10. Maximal-entropy random walk unifies centrality measures.

    Science.gov (United States)

    Ochab, J K

    2012-12-01

    This paper compares a number of centrality measures and several (dis-)similarity matrices with which they can be defined. These matrices, which are used among others in community detection methods, represent quantities connected to enumeration of paths on a graph and to random walks. Relationships between some of these matrices are derived in the paper. These relationships are inherited by the centrality measures. They include measures based on the principal eigenvector of the adjacency matrix, path enumeration, as well as on the stationary state, stochastic matrix, or mean first-passage times of a random walk. As the random walk defining the centrality measure can be arbitrarily chosen, we pay particular attention to the maximal-entropy random walk, which serves as a very distinct alternative to the ordinary (diffusive) random walk used in network analysis. The various importance measures, defined both with the use of ordinary random walk and the maximal-entropy random walk, are compared numerically on a set of benchmark graphs with varying mixing parameter and are grouped with the use of the agglomerative clustering technique. It is shown that centrality measures defined with the two different random walks cluster into two separate groups. In particular, the group of centrality measures defined by the maximal-entropy random walk does not cluster with any other measures on change of graphs' parameters, and members of this group produce mutually closer results than members of the group defined by the ordinary random walk.

  11. Prediction of maximal aerobic capacity in severely burned children.

    Science.gov (United States)

    Porro, Laura; Rivero, Haidy G; Gonzalez, Dante; Tan, Alai; Herndon, David N; Suman, Oscar E

    2011-06-01

    Maximal oxygen uptake (VO₂ peak) is an indicator of cardiorespiratory fitness, but requires expensive equipment and a relatively high technical skill level. The aim of this study is to provide a formula for estimating VO₂ peak in burned children, using information obtained without expensive equipment. Children, with ≥ 40% total surface area burned (TBSA), underwent a modified Bruce treadmill test to assess VO(2) peak at 6 months after injury. We recorded gender, age, %TBSA, %3rd degree burn, height, weight, treadmill time, maximal speed, maximal grade, and peak heart rate, and applied McHenry's select algorithm to extract important independent variables and Robust multiple regression to establish prediction equations. 42 children; 7-17 years old were tested. Robust multiple regression model provided the equation: VO₂ =10.33-0.62 × age (years)+1.88 × treadmill time (min)+2.3 (gender; females = 0, males = 1). The correlation between measured and estimated VO₂ peak was R = 0.80. We then validated the equation with a group of 33 burned children, which yielded a correlation between measured and estimated VO₂ peak of R = 0.79. Using only a treadmill and easily gathered information, VO₂ peak can be estimated in children with burns. Copyright © 2011 Elsevier Ltd and ISBI. All rights reserved.

  12. Effect of sonic driving on maximal aerobic performance.

    Science.gov (United States)

    Brilla, L.R.; Hatcher, Stefanie

    2000-07-01

    The study purpose was to evaluate antecedent binaural stimulation (ABS) on maximal aerobic physical performance. Twenty-two healthy, physically active subjects, 21-34 years, randomly received one of two preparations for each session: 15 min of quiet (BLANK) or percussive sonic driving at 200+ beats per minute (bpm) using a recorded compact disc (FSS, Mill Valley, CA) with headphones (ABS). Baseline HR, blood pressure (BP), and breathing frequency (f(br)) were obtained. During each condition, HR and f(br) were recorded at 3-min intervals. The graded maximal treadmill testing was administered immediately postpreparation session on separate days, with at least 48 h rest between sessions. There were significant differences in the antecedent period means between the two conditions, ABS (HR: 70.2 +/- 10.7 bpm; f(br): 18.5 +/- 3.3 br min(-1); BP: 134.5/87.9 +/- 13.6/9.2 mm Hg) and BLANK (HR: 64.6 +/- 7.9; f(br): 14.3 +/- 2.9; BP: 126.7/80.3 +/- 12.1/8.6). Differences were noted for each 3-min interval and pre- postantecedent period. The maximal graded exercise test (GXT) results showed that there was a small but significant (P 0.05). There may be a latency to ABS related to entrainment or imagery-enhanced warm-up. Am. J. Hum. Biol. 12:558-565, 2000. Copyright 2000 Wiley-Liss, Inc.

  13. Polarity related influence maximization in signed social networks.

    Science.gov (United States)

    Li, Dong; Xu, Zhi-Ming; Chakraborty, Nilanjan; Gupta, Anika; Sycara, Katia; Li, Sheng

    2014-01-01

    Influence maximization in social networks has been widely studied motivated by applications like spread of ideas or innovations in a network and viral marketing of products. Current studies focus almost exclusively on unsigned social networks containing only positive relationships (e.g. friend or trust) between users. Influence maximization in signed social networks containing both positive relationships and negative relationships (e.g. foe or distrust) between users is still a challenging problem that has not been studied. Thus, in this paper, we propose the polarity-related influence maximization (PRIM) problem which aims to find the seed node set with maximum positive influence or maximum negative influence in signed social networks. To address the PRIM problem, we first extend the standard Independent Cascade (IC) model to the signed social networks and propose a Polarity-related Independent Cascade (named IC-P) diffusion model. We prove that the influence function of the PRIM problem under the IC-P model is monotonic and submodular Thus, a greedy algorithm can be used to achieve an approximation ratio of 1-1/e for solving the PRIM problem in signed social networks. Experimental results on two signed social network datasets, Epinions and Slashdot, validate that our approximation algorithm for solving the PRIM problem outperforms state-of-the-art methods.

  14. Pacing pattern in a 30-minute maximal cycling test.

    Science.gov (United States)

    Chaffin, Morgan E; Berg, Kris; Zuniga, Jorge; Hanumanthu, Vidya Sagar

    2008-11-01

    The purpose of this study was to investigate the pacing pattern and associated physiological effects in competitive cyclists who performed a 30-minute maximal cycling test. Measurements included oxygen uptake (V O2), heart rate (HR), blood lactate concentration (BLC), rating of perceived exertion (RPE), and work rate in watts. Twelve well-trained amateur cyclists (seven men and five women) whose mean age was 32.4 +/- 8.6 years participated in this study. They performed a 30-minute self-paced maximal cycling test using their own performance road bike attached to a CompuTrainer Pro, which allowed the assessment of work rate (W). During the test, work rate, V O2, and HR were measured every 30 seconds. Subjects' BLC and RPE were obtained every 5 minutes. Results indicate that no significant differences existed across three 10-minute periods for work rate, HR, or V O2. However, RPE at 30 minutes was significantly greater than RPE at 10 and 20 minutes (both p minutes was also greater than the RPE at 10 minutes (p 30 seconds of the test. The associated V O2 was fairly constant over time, whereas HR rose linearly and gradually. It was concluded that pacing in a 30-minute maximal exercise bout performed in the laboratory in experienced cyclists varies minimally until the last 30 seconds. Knowledge of pacing strategy and the linked physiological responses may be helpful to exercise scientists in optimizing performance in the endurance athlete.

  15. Planning Routes Across Economic Terrains: Maximizing Utility, Following Heuristics

    Science.gov (United States)

    Zhang, Hang; Maddula, Soumya V.; Maloney, Laurence T.

    2010-01-01

    We designed an economic task to investigate human planning of routes in landscapes where travel in different kinds of terrain incurs different costs. Participants moved their finger across a touch screen from a starting point to a destination. The screen was divided into distinct kinds of terrain and travel within each kind of terrain imposed a cost proportional to distance traveled. We varied costs and spatial configurations of terrains and participants received fixed bonuses minus the total cost of the routes they chose. We first compared performance to a model maximizing gain. All but one of 12 participants failed to adopt least-cost routes and their failure to do so reduced their winnings by about 30% (median value). We tested in detail whether participants’ choices of routes satisfied three necessary conditions (heuristics) for a route to maximize gain. We report failures of one heuristic for 7 out of 12 participants. Last of all, we modeled human performance with the assumption that participants assign subjective utilities to costs and maximize utility. For 7 out 12 participants, the fitted utility function was an accelerating power function of actual cost and for the remaining 5, a decelerating power function. We discuss connections between utility aggregation in route planning and decision under risk. Our task could be adapted to investigate human strategy and optimality of route planning in full-scale landscapes. PMID:21833269

  16. Maximal trace distance between isoenergetic bosonic Gaussian states

    Science.gov (United States)

    Volkoff, T. J.

    2017-12-01

    We locate the set of pairs (ρ1, ρ2) of Gaussian states of a single mode electromagnetic field that exhibit maximal trace distance subject to the energy constraint ⟨a†a⟩ ρ1=⟨a†a⟩ ρ2=E . Any such pair allows to achieve the minimum possible error in the task of binary distinguishability of two single mode, isoenergetic Gaussian quantum signals. In particular, we show that the logarithm of the minimal error probability for distinguishing two maximally trace distant, isoenergetic Gaussian states scales as -E2, less than the achievable scaling of the minimal error probability for distinguishing, e.g., a pair of isoenergetic Heisenberg-Weyl coherent states with energy E or a pair of isoenergetic quadrature squeezed states with energy E. For the case of a field consisting of M > 1 modes, we locate the set of pairs of maximally trace distant isoenergetic, isocovariant Gaussian states. These results have basic applications in the theory of continuous variable quantum communications with Gaussian states of light.

  17. An efficient community detection algorithm using greedy surprise maximization

    International Nuclear Information System (INIS)

    Jiang, Yawen; Jia, Caiyan; Yu, Jian

    2014-01-01

    Community detection is an important and crucial problem in complex network analysis. Although classical modularity function optimization approaches are widely used for identifying communities, the modularity function (Q) suffers from its resolution limit. Recently, the surprise function (S) was experimentally proved to be better than the Q function. However, up until now, there has been no algorithm available to perform searches to directly determine the maximal surprise values. In this paper, considering the superiority of the S function over the Q function, we propose an efficient community detection algorithm called AGSO (algorithm based on greedy surprise optimization) and its improved version FAGSO (fast-AGSO), which are based on greedy surprise optimization and do not suffer from the resolution limit. In addition, (F)AGSO does not need the number of communities K to be specified in advance. Tests on experimental networks show that (F)AGSO is able to detect optimal partitions in both simple and even more complex networks. Moreover, algorithms based on surprise maximization perform better than those algorithms based on modularity maximization, including Blondel–Guillaume–Lambiotte–Lefebvre (BGLL), Clauset–Newman–Moore (CNM) and the other state-of-the-art algorithms such as Infomap, order statistics local optimization method (OSLOM) and label propagation algorithm (LPA). (paper)

  18. Trunk muscle activation during sub-maximal extension efforts.

    Science.gov (United States)

    Olson, Michael W

    2010-02-01

    Neuromuscular fatigue of the trunk musculature, particularly lumbar paraspinal and abdominal muscles, is important in when evaluating motor control of the trunk. Activation of agonists and antagonists trunk muscles was hypothesized to change during sub-maximal isometric trunk extension efforts. Thirteen women were positioned in 30 degrees of trunk flexion and performed maximal voluntary isometric contraction in trunk extension against an isokinetic dynamometer. One of two sub-maximal efforts (50% and 70%) was performed to induce neuromuscular fatigue on two different days. Surface electromyography of the lumbar paraspinal (LP), rectus abdominis, and external oblique muscles was recorded during each session. Torque output, median frequency of the power density spectrum, and normalized integrated electromyography were analyzed using repeated measures analysis of variance to evaluate trends in the data over time. Paraspinal muscles showed signs of fatigue in both conditions (pAbdominal activity did not increase during the 70% condition, but showed a non-significant trend (p=0.07), coinciding with the reduced median frequency of LP muscles. The neuromuscular system modulates its motor control strategy to identify the muscle activation levels necessary to maintain force output. This information is necessary in the evaluation of contributing mechanisms to trunk stability in furthering preventative and rehabilitative treatments.

  19. Effect of concurrent training, flexible nonlinear periodization, and maximal-effort cycling on strength and power.

    Science.gov (United States)

    McNamara, John M; Stearne, David J

    2013-06-01

    Although there is considerable research on concurrent training, none has integrated flexible nonlinear periodization and maximal-effort cycling in the same design. The purpose of this investigation was to test outcome measures of strength and power using a pretest-posttest randomized groups design. A strength and endurance (SE) group was compared with a strength, endurance, and maximal-effort cycling (SEC) group. Both groups used a flexible nonlinear periodization design. Thirteen male and 7 female students (mean ± SD: age, 22.5 ± 4.1 years; height, 173.5 ± 12.4 cm; weight, 79.4 ± 20.2 kg; strength training experience, 2.4 ± 2.2 years) participated in this study. Groups were not matched for age, height, weight, strength training experience, or sex, but were randomly assigned to an SE (n = 10) or SEC (n = 10) group. All training was completed within 45 minutes, twice per week (Monday and Wednesday), over 12 consecutive weeks. Both groups were assigned 6.75 total hours of aerobic conditioning, and 13.5 hours of free weight and machine exercises totaling 3,188 repetitions ranging from 5 to 20 repetition maximums. The SEC group performed 2 cycling intervals per workout ranging from 10 to 45 seconds. Pretest and posttest measures included chest press and standing broad jump. Analysis of variance showed that there were no significant differences between the SE and SEC groups on measures of chest press or standing broad jump performance (p, not significant). Paired sample t-tests (p = 0.05) showed significant improvement in strength and power in all groups (pretest to posttest), except for SE jump performance (p, not significant). In conclusion, adding maximal-effort cycling does not provide additional strength or power benefits to a concurrent flexible nonlinear training program. However, an exercise professional can take confidence that a concurrent flexible nonlinear training program can increase strength and power in healthy individuals.

  20. An Analysis of Maxims in Susilo Bambang Yudhoyono’s Political Speeches

    OpenAIRE

    Pasaribu, Mestika

    2015-01-01

    Thesis entitled " An Analysis of Maxims in Susilo Bambang Yudhoyono 's Political Speeches " is an analysis of the application of the maxim in his speech Yudhoyono . Theoretical basis used is the theory Geoffrey Leech (1983 ) which describes the level of politeness with the use of the maxim . This research uses descriptive qualitative method . This study aims to determine the types of maxims used by Susilo Bambang Yudhoyono and the most dominant maxim used Susilo Bambang Yudhoyono in his polit...

  1. Gas analyzer’s drift leads to systematic error in maximal oxygen uptake and maximal respiratory exchange ratio determination

    Directory of Open Access Journals (Sweden)

    Ibai eGarcia-Tabar

    2015-10-01

    Full Text Available The aim was to examine the drift in the measurements of fractional concentration of oxygen (FO2 and carbon dioxide (FCO2 of a Nafion-using metabolic cart during incremental maximal exercise in 18 young and 12 elderly males, and to propose a way in which the drift can be corrected. The drift was verified by comparing the pre-test calibration values with the immediate post-test verification values of the calibration gases. The system demonstrated an average downscale drift (P < 0.001 in FO2 and FCO2 of -0.18% and -0.05%, respectively. Compared with measured values, corrected average maximal oxygen uptake values were 5-6% lower (P < 0.001 whereas corrected maximal respiratory exchange ratio values were 8-9% higher (P < 0.001. The drift was not due to an electronic instability in the analyzers because it was reverted after 20 minutes of recovery from the end of the exercise. The drift may be related to an incomplete removal of water vapor from the expired gas during transit through the Nafion conducting tube. These data demonstrate the importance of checking FO2 and FCO2 values by regular pre-test calibrations and post-test verifications, and also the importance of correcting a possible shift immediately after exercise.

  2. Descriptive Analysis on Flouting and Hedging of Conversational Maxims in the “Post Grad” Movie

    Directory of Open Access Journals (Sweden)

    Nastiti Rokhmania

    2012-11-01

    Full Text Available This research is focused on analyzing flouting and hedging of conversational maxim of utterances used by the main characters in “Post Grad” movie. Conversational maxims are the rules of cooperative principle categorized into four categories; Maxim of Quality, Maxim of Quantity, Maxim of Relevance, and Maxim of Manner. If these maxims are used in conversations, the conversations can go smoothly. However, people often break the maxims overtly (flouting maxim and sometimes break the maxims secretly (hedging maxims when they make a conversation. This research is conducted using descriptive qualitative method based on the theory known as Grice’s Maxims. The data are in form of utterances used by the characters in “Post Grad” movie. The data analysis reveals some finding covering the formulated research question. The maxims are flouted when the speaker breaks some conversational maxims when using the utterances in the form of rhetorical strategies, such as tautology, metaphor, hyperbole, irony, and rhetorical question. On the other hand, conversational maxims are also hedged when the information is not totally accurate or unclearly stated but seems informative, well-founded, and relevant.

  3. EFFECTS OF MAXIMAL SQUAT EXERCISE TESTING ON VERTICAL JUMP PERFORMANCE IN AMERICAN COLLEGE FOOTBALL PLAYERS

    Directory of Open Access Journals (Sweden)

    Jay R. Hoffman

    2007-03-01

    Full Text Available Maximal strength and power testing are common assessments that are used to evaluate strength/power athletes. The validity and reliability of these tests have been well established (Hoffman, 2006, however the order of testing may have a profound effect on test performance outcome. It is generally recommended that the least fatiguing and highly-skilled tests are performed first, while highly fatiguing tests are performed last (Hoffman, 2006. Recent research has demonstrated that maximal isometric contractions and maximal or near- maximal dynamic exercise can augment the rate of force development, increase jump height and enhance sprint cycle performance (Chiu et al., 2003; French et al., 2003. The use of a maximal or near-maximal activity to enhance strength and power performance has been termed "muscle postactivation potentiation", and appears to be more common in the experienced resistance-trained athletes than in the recreationally-trained population (Chiu et al., 2003. It is believed that postactivation potentiation can enhance muscle performance by increasing the neural signal that activates the muscle (Hamada et al., 2000. Since heavy loading in a similar movement pattern of exercise appears to enhance maximal strength and power performance in the experienced resistance-trained athlete, it may be hypothesized that the postactivation potentiation associated with heavy loading has the potential to augment subsequent performance of tests utilizing similar motion. Therefore, consideration of an appropriate sequence of athletic performance testing in strength and power athletes is warranted. We would like to share our experience on the effect of performing a maximal lower body strength test on vertical jump performance in experienced resistance-trained strength/power athletes.We examined 64 NCAA Division III American collegiate football players (age = 20.1 ± 1.9 yr; body mass = 97.5 ± 17.8 kg; height = 1.80 ± 0.12 m. All testing was performed

  4. Patient-specific rhytidectomy: finding the angle of maximal rejuvenation.

    Science.gov (United States)

    Jacono, Andrew A; Ransom, Evan R

    2012-09-01

    Rhytidectomy is fundamentally an operation of tissue release and resuspension, although the manner and direction of suspension are subject to perpetual debate. The authors describe a method for identifying the angle of maximal rejuvenation during rhytidectomy and quantify the resulting angle and its relationship to patient age. Patients were prospectively enrolled; demographic data, history, and operative details were recorded. Rhytidectomies were performed by the senior author (AAJ). After complete elevation, the face-lift flap was rotated in a medially-based arc (0-90°) while attention was given to the submental area, jawline, and midface. The angle of maximal rejuvenation for each hemiface was identified as described, and the flap was resuspended. During redraping, measurements of vertical and horizontal skin excess were recorded in situ. The resulting angle of lift was then calculated for each hemiface using trigonometry. Symmetry between sides was determined, and the effect of patient age on this angle was assessed. Three hundred hemifaces were operated (147 women; 3 men). Mean age was 60 years (range, 37-80 years). Mean resulting angle for the cohort was 60° from horizontal (range, 46-77°). This was inversely correlated with patient age (r = -.3). Younger patients (<50 years, 64°) had a significantly more vertical angle than older patients (≥70 years, 56°; P < .0002). No significant intersubject difference was found between hemifaces (P = .53). The authors present a method for identifying the angle of maximal rejuvenation during rhytidectomy. This angle was more superior than posterior in all cases and is intimately related to patient age. Lasting results demand a detailed anatomical understanding and strict attention to the direction and degree of laxity.

  5. Maximal exercise at extreme altitudes on Mount Everest.

    Science.gov (United States)

    West, J B; Boyer, S J; Graber, D J; Hackett, P H; Maret, K H; Milledge, J S; Peters, R M; Pizzo, C J; Samaja, M; Sarnquist, F H

    1983-09-01

    Maximal exercise at extreme altitudes was studied during the course of the American Medical Research Expedition to Everest. Measurements were carried out at sea level [inspired O2 partial pressure (PO2) 147 Torr], 6,300 m during air breathing (inspired PO2 64 Torr), 6,300 m during 16% O2 breathing (inspired PO2 49 Torr), and 6,300 m during 14% O2 breathing (inspired PO2 43 Torr). The last PO2 is equivalent to that on the summit of Mt. Everest. All the 6,300 m studies were carried out in a warm well-equipped laboratory on well-acclimatized subjects. Maximal O2 uptake fell dramatically as the inspired PO2 was reduced to very low levels. However, two subjects were able to reach an O2 uptake of 1 l/min at the lowest inspired PO2. Arterial O2 saturations fell markedly and alveolar-arterial PO2 differences increased as the work rate was raised at high altitude, indicating diffusion limitation of O2 transfer. Maximal exercise ventilations exceeded 200 l/min at 6,300 m during air breathing but fell considerably at the lowest values of inspired PO2. Alveolar CO2 partial pressure was reduced to 7-8 Torr in one subject at the lowest inspired PO2, and the same value was obtained from alveolar gas samples taken by him at rest on the summit. The results help to explain how man can reach the highest point on earth while breathing ambient air.

  6. Informatics knowledge: the key to maximizing performance and productivity.

    Science.gov (United States)

    Sinclair, V G

    1997-06-01

    Nurse managers face a competitive and complex market-place that demands greater attention to customer satisfaction along with continual improvements in quality and cost-effectiveness. Without information technology, the manager cannot hope to deliver ever greater quality at less cost. The nurse managers' effective promotion and use of computer applications can have enormous impact on the performance and productivity of their health care facilities. This article explores the potential of information technology to maximize clinical and cost outcomes, optimize decision making, and enhance administrative productivity.

  7. Maximizing Shelf Life of Paneer-A Review.

    Science.gov (United States)

    Goyal, Sumit; Goyal, Gyanendra Kumar

    2016-06-10

    Paneer resembling soft cheese is a well-known heat- and acid-coagulated milk product. It is very popular in the Indian subcontinent and has appeared in the western and Middle East markets. The shelf life of paneer is quite low and it loses freshness after two to three days when stored under refrigeration. Various preservation techniques, including chemical additives, packaging, thermal processing, and low-temperature storage, have been proposed by researchers for enhancing its shelf life. The use of antimicrobial additives is not preferred because of perceived toxicity risks. Modified atmosphere packaging has been recommended as one of the best techniques for maximizing the shelf life of paneer.

  8. Maximal heat loading of electrostatic deflector's septum at the cyclotron

    International Nuclear Information System (INIS)

    Arzumanov, A.; Borissenko, A.

    2002-01-01

    An electrostatic deflector is used for extraction of accelerated particles at the isochronous cyclotron U-150 (Institute of Nuclear Physics, Kazakhstan). Efficiency of beam extraction depends on a set of factors. Decisive is heat state of the septum and essentially beam extraction is limited by beam power dissipation on the deflector. Due to the works carried on for radioisotope production, determination of septum's maximal heat loading, optimization of the septum's geometry represent the interest. Maximum heat loading of deflector's septum and it's dependence on septum's geometry and thermal-physical properties of septum's material are presented in the paper as result of numerical calculation. The obtained results are discussed

  9. Eccentric exercise decreases maximal insulin action in humans

    DEFF Research Database (Denmark)

    Asp, Svend; Daugaard, J R; Kristiansen, S

    1996-01-01

    subjects participated in two euglycaemic clamps, performed in random order. One clamp was preceded 2 days earlier by one-legged eccentric exercise (post-eccentric exercise clamp (PEC)) and one was without the prior exercise (control clamp (CC)). 2. During PEC the maximal insulin-stimulated glucose uptake...... over the eccentric thigh was marginally lower when compared with the control thigh, (11.9%, 64.6 +/- 10.3 vs. 73.3 +/- 10.2 mumol kg-1 min-1, P = 0.08), whereas no inter-thigh difference was observed at a submaximal insulin concentration. The glycogen concentration was lower in the eccentric thigh...

  10. Gribov ambiguities at the Landau-maximal Abelian interpolating gauge

    Energy Technology Data Exchange (ETDEWEB)

    Pereira, Antonio D.; Sobreiro, Rodrigo F. [UFF-Universidade Federal Fluminense, Instituto de Fisica, Niteroi, RJ (Brazil)

    2014-08-15

    In a previous work, we presented a new method to account for the Gribov ambiguities in non-Abelian gauge theories. The method consists on the introduction of an extra constraint which directly eliminates the infinitesimal Gribov copies without the usual geometric approach. Such strategy allows one to treat gauges with non-hermitian Faddeev-Popov operator. In this work, we apply this method to a gauge which interpolates among the Landau and maximal Abelian gauges. The result is a local and power counting renormalizable action, free of infinitesimal Gribov copies. Moreover, the interpolating tree-level gluon propagator is derived. (orig.)

  11. The one-sided Ap conditions and local maximal operator

    Czech Academy of Sciences Publication Activity Database

    Bernardis, A.L.; Gogatishvili, Amiran; Martin-Reyes, F. J.; Ortega Salvador, P.; Pick, L.

    2012-01-01

    Roč. 55, č. 1 (2012), s. 79-104 ISSN 0013-0915 R&D Projects: GA ČR GA201/08/0383; GA ČR GA201/05/2033 Institutional research plan: CEZ:AV0Z10190503 Keywords : one-sided Ap conditions * one-sided local maximal operator * quasi- Banach function spaces * variable-exponent Lebesgue spaces Subject RIV: BA - General Mathematics Impact factor: 0.561, year: 2012 http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8477114&fulltextType=RA&fileId=S0013091510000635

  12. The one-sided Ap conditions and local maximal operator

    Czech Academy of Sciences Publication Activity Database

    Bernardis, A.L.; Gogatishvili, Amiran; Martin-Reyes, F. J.; Ortega Salvador, P.; Pick, L.

    Roč. 55, č. 1 ( 2012 ), s. 79-104 ISSN 0013-0915 R&D Projects: GA ČR GA201/08/0383; GA ČR GA201/05/2033 Institutional research plan: CEZ:AV0Z10190503 Keywords : one-sided Ap conditions * one-sided local maximal operator * quasi-Banach function spaces * variable-exponent Lebesgue spaces Subject RIV: BA - General Mathematics Impact factor: 0.561, year: 2012 http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8477114&fulltextType=RA&fileId=S0013091510000635

  13. Maximizing Team Performance: The Critical Role of the Nurse Leader.

    Science.gov (United States)

    Manges, Kirstin; Scott-Cawiezell, Jill; Ward, Marcia M

    2017-01-01

    Facilitating team development is challenging, yet critical for ongoing improvement across healthcare settings. The purpose of this exemplary case study is to examine the role of nurse leaders in facilitating the development of a high-performing Change Team in implementing a patient safety initiative (TeamSTEPPs) using the Tuckman Model of Group Development as a guiding framework. The case study is the synthesis of 2.5 years of critical access hospital key informant interviews (n = 50). Critical juncture points related to team development and key nurse leader actions are analyzed, suggesting that nurse leaders are essential to maximize clinical teams' performance. © 2016 Wiley Periodicals, Inc.

  14. Economic strategies to maximize profits from satellite field developments

    International Nuclear Information System (INIS)

    Antia, D.D.J.

    1994-01-01

    The main strategies that can be used to maximize profits from integrated satellite field developments are: (1) restructuring the cost, production and revenue profile of the satellite field; and (2) increasing the volume of oil/gas processed, and available for future use, by the central processing and distribution facility through: (a) using a combined strategy of low tariffs, volume discount, and netback agreements; (b) using reusable facilities, shared facilities, extended reach wells, contractor finance, partnering agreements, netback agreements, oil/gas price swaps; and (c) improving development, discovery and exploration efficiency

  15. Software development with C++ maximizing reuse with object technology

    CERN Document Server

    Nielsen, Kjell

    2014-01-01

    Software Development with C++: Maximizing Reuse with Object Technology is about software development and object-oriented technology (OT), with applications implemented in C++. The basis for any software development project of complex systems is the process, rather than an individual method, which simply supports the overall process. This book is not intended as a general, all-encompassing treatise on OT. The intent is to provide practical information that is directly applicable to a development project. Explicit guidelines are offered for the infusion of OT into the various development phases.

  16. MaxAlign: maximizing usable data in an alignment

    DEFF Research Database (Denmark)

    Oliveira, Rodrigo Gouveia; Sackett, Peter Wad; Pedersen, Anders Gorm

    2007-01-01

    the alignment prior to such analyses. Specifically, it maximizes the number of nucleotide (or amino acid) symbols that are present in gap-free columns - the alignment area - by selecting the optimal subset of sequences to exclude from the alignment. MaxAlign can be used prior to phylogenetic and bioinformatical......Align. In this paper we also introduce a new simple measure of tree similarity, Normalized Symmetric Similarity (NSS) that we consider useful for comparing tree topologies. CONCLUSION: We demonstrate how MaxAlign is helpful in detecting misaligned or defective sequences without requiring manual inspection. We also...

  17. Maximal lens bounds on QSO-galaxy association

    International Nuclear Information System (INIS)

    Kovner, I.

    1989-01-01

    The maximal possible enhancement of QSO number counts that can be produced by any ensemble of lenses which conserve brightness and in which the magnification probability is negligibly correlated with the intrinsic QSO flux is obtained. Under the assumption of the Boyle et al. (1988) number-magnitude relation for the QSOs unaffected by lenses, the theory is applied to the QSO-galaxy association sample of Webster et al. (1988). The results suggest that the background QSOs of Webster et al. may be appreciably affected by lensing. 17 refs

  18. Determinants of maximal oxygen uptake in severe acute hypoxia

    DEFF Research Database (Denmark)

    Calbet, J A L; Boushel, Robert Christopher; Rådegran, G

    2003-01-01

    , as reflected by the higher alveolar-arterial O2 difference in hypoxia (P rate and stroke VOlume (P ... level). With hypoxia, exercise PaO2 dropped to 31-34 mmHg and arterial O2 content (CaO2) was reduced by 35% (P exchange......: 1) reduction of PiO2, 2) impairment of pulmonary gas exchange, and 3) reduction of maximal cardiac output and peak leg blood flow, each explaining about one-third of the loss in VO2 max....

  19. Stochastic convolutions driven by martingales: maximal inequalities and exponential integrability

    Czech Academy of Sciences Publication Activity Database

    Hausenblas, E.; Seidler, Jan

    2008-01-01

    Roč. 26, č. 1 (2008), s. 98-119 ISSN 0736-2994 Grant - others:Austrian Academy of Sciences(AT) APART 700; GA ČR(CZ) GA201/04/0750; GA ČR(CZ) GA201/01/1197; GA MSM(CZ) Kontakt 2001-05 Program:GA; GA Institutional research plan: CEZ:AV0Z10750506 Source of funding: V - iné verejné zdroje ; V - iné verejné zdroje Keywords : maximal inequality * exponential tail estimates * stochastic convolution Subject RIV: BA - General Mathematics Impact factor: 0.528, year: 2008

  20. Learning to maximize reward rate: a model based on semi-Markov decision processes.

    Science.gov (United States)

    Khodadadi, Arash; Fakhari, Pegah; Busemeyer, Jerome R

    2014-01-01

    WHEN ANIMALS HAVE TO MAKE A NUMBER OF DECISIONS DURING A LIMITED TIME INTERVAL, THEY FACE A FUNDAMENTAL PROBLEM: how much time they should spend on each decision in order to achieve the maximum possible total outcome. Deliberating more on one decision usually leads to more outcome but less time will remain for other decisions. In the framework of sequential sampling models, the question is how animals learn to set their decision threshold such that the total expected outcome achieved during a limited time is maximized. The aim of this paper is to provide a theoretical framework for answering this question. To this end, we consider an experimental design in which each trial can come from one of the several possible "conditions." A condition specifies the difficulty of the trial, the reward, the penalty and so on. We show that to maximize the expected reward during a limited time, the subject should set a separate value of decision threshold for each condition. We propose a model of learning the optimal value of decision thresholds based on the theory of semi-Markov decision processes (SMDP). In our model, the experimental environment is modeled as an SMDP with each "condition" being a "state" and the value of decision thresholds being the "actions" taken in those states. The problem of finding the optimal decision thresholds then is cast as the stochastic optimal control problem of taking actions in each state in the corresponding SMDP such that the average reward rate is maximized. Our model utilizes a biologically plausible learning algorithm to solve this problem. The simulation results show that at the beginning of learning the model choses high values of decision threshold which lead to sub-optimal performance. With experience, however, the model learns to lower the value of decision thresholds till finally it finds the optimal values.

  1. Maximizing opto‐mechanical interaction using topology optimization

    DEFF Research Database (Denmark)

    Gersborg, Allan Roulund; Sigmund, Ole

    2011-01-01

    This paper studies topology optimization of a coupled opto‐mechanical problem with the goal of finding the material layout which maximizes the optical modulation, i.e. the difference between the optical response for the mechanically deformed and undeformed configuration. The optimization is perfo......This paper studies topology optimization of a coupled opto‐mechanical problem with the goal of finding the material layout which maximizes the optical modulation, i.e. the difference between the optical response for the mechanically deformed and undeformed configuration. The optimization...... is performed on a periodic cell and the periodic modeling of the optical and mechanical fields have been carried out using transverse electric Bloch waves and homogenization theory in a plane stress setting, respectively. Two coupling effects are included being the photoelastic effect and the geometric effect...... caused by the mechanical deformation. For the studied objective and material choice it is concluded that the photoelastic effect and the geometric effect counteract each other, which yields designs which are fundamentally different if the optimization takes only one effect into account. When both effects...

  2. Understanding the factors that effect maximal fat oxidation.

    Science.gov (United States)

    Purdom, Troy; Kravitz, Len; Dokladny, Karol; Mermier, Christine

    2018-01-01

    Lipids as a fuel source for energy supply during submaximal exercise originate from subcutaneous adipose tissue derived fatty acids (FA), intramuscular triacylglycerides (IMTG), cholesterol and dietary fat. These sources of fat contribute to fatty acid oxidation (FAox) in various ways. The regulation and utilization of FAs in a maximal capacity occur primarily at exercise intensities between 45 and 65% VO 2max , is known as maximal fat oxidation (MFO), and is measured in g/min. Fatty acid oxidation occurs during submaximal exercise intensities, but is also complimentary to carbohydrate oxidation (CHOox). Due to limitations within FA transport across the cell and mitochondrial membranes, FAox is limited at higher exercise intensities. The point at which FAox reaches maximum and begins to decline is referred to as the crossover point. Exercise intensities that exceed the crossover point (~65% VO 2max ) utilize CHO as the predominant fuel source for energy supply. Training status, exercise intensity, exercise duration, sex differences, and nutrition have all been shown to affect cellular expression responsible for FAox rate. Each stimulus affects the process of FAox differently, resulting in specific adaptions that influence endurance exercise performance. Endurance training, specifically long duration (>2 h) facilitate adaptations that alter both the origin of FAs and FAox rate. Additionally, the influence of sex and nutrition on FAox are discussed. Finally, the role of FAox in the improvement of performance during endurance training is discussed.

  3. Biomechanical characteristics of handballing maximally in Australian football.

    Science.gov (United States)

    Parrington, Lucy; Ball, Kevin; MacMahon, Clare

    2014-11-01

    The handball pass is influential in Australian football, and achieving higher ball speeds in flight is an advantage in increasing distance and reducing the chance of interceptions. The purpose of this study was to provide descriptive kinematic data and identify key technical aspects of maximal handball performance. Three-dimensional full body kinematic data from 19 professional Australian football players performing handball pass for maximal speed were collected, and the hand speed at ball contact was used to determine performance. Sixty-four kinematic parameters initially obtained were reduced to 15, and then grouped into like components through a two-stage supervised principal components analysis procedure. These components were then entered into a multiple regression analysis, which indicated that greater hand speed was associated with greater shoulder angular velocity and separation angle between the shoulders and pelvis at ball contact, as well as an earlier time of maximum upper-trunk rotation velocity. These data suggested that in order to increase the speed of the handball pass in Australian football, strategies like increased shoulder angular velocity, increased separation angle at ball contact, and earlier achievement of upper-trunk rotation speed might be beneficial.

  4. Consumer-driven profit maximization in broiler production and processing

    Directory of Open Access Journals (Sweden)

    Ecio de Farias Costa

    2004-01-01

    Full Text Available Increased emphasis on consumer markets in broiler profit-maximizing modeling generates results that differ from those by traditional profit-maximization models. This approach reveals that the adoption of step pricing and consideration of marketing options (examples of responsiveness to consumers affect the optimal feed formulation levels and types of broiler production to generate maximum profitability. The adoption of step pricing attests that higher profits can be obtained for targeted weights only if premium prices for broiler products are contracted.Um aumento na ênfase dada ao mercado de consumidores de carne de frango e modelos de maximização de lucros na produção de frangos de corte geram resultados que diferem daqueles obtidos em modelos tradicionais de maximização de lucros. Esta metodologia revela que a adoção de step-pricing e considerando opções de mercado (exemplos de resposta às preferências de consumidores afetam os níveis ótimos de formulação de rações e os tipos de produção de frangos de corte que geram uma lucratividade máxima. A adoção de step-pricing atesta que maiores lucros podem ser obtidos para pesos-alvo somente se preços-prêmio para produtos processados de carne de frango forem contratados.

  5. Maximizing Lifetime of Wireless Sensor Networks with Mobile Sink Nodes

    Directory of Open Access Journals (Sweden)

    Yourong Chen

    2014-01-01

    Full Text Available In order to maximize network lifetime and balance energy consumption when sink nodes can move, maximizing lifetime of wireless sensor networks with mobile sink nodes (MLMS is researched. The movement path selection method of sink nodes is proposed. Modified subtractive clustering method, k-means method, and nearest neighbor interpolation method are used to obtain the movement paths. The lifetime optimization model is established under flow constraint, energy consumption constraint, link transmission constraint, and other constraints. The model is solved from the perspective of static and mobile data gathering of sink nodes. Subgradient method is used to solve the lifetime optimization model when one sink node stays at one anchor location. Geometric method is used to evaluate the amount of gathering data when sink nodes are moving. Finally, all sensor nodes transmit data according to the optimal data transmission scheme. Sink nodes gather the data along the shortest movement paths. Simulation results show that MLMS can prolong network lifetime, balance node energy consumption, and reduce data gathering latency under appropriate parameters. Under certain conditions, it outperforms Ratio_w, TPGF, RCC, and GRND.

  6. Quantum coherence generating power, maximally abelian subalgebras, and Grassmannian geometry

    Science.gov (United States)

    Zanardi, Paolo; Campos Venuti, Lorenzo

    2018-01-01

    We establish a direct connection between the power of a unitary map in d-dimensions (d algebra). This set can be seen as a topologically non-trivial subset of the Grassmannian over linear operators. The natural distance over the Grassmannian induces a metric structure on Md, which quantifies the lack of commutativity between the pairs of subalgebras. Given a maximally abelian subalgebra, one can define, on physical grounds, an associated measure of quantum coherence. We show that the average quantum coherence generated by a unitary map acting on a uniform ensemble of quantum states in the algebra (the so-called coherence generating power of the map) is proportional to the distance between a pair of maximally abelian subalgebras in Md connected by the unitary transformation itself. By embedding the Grassmannian into a projective space, one can pull-back the standard Fubini-Study metric on Md and define in this way novel geometrical measures of quantum coherence generating power. We also briefly discuss the associated differential metric structures.

  7. Theoretical maximal storage of hydrogen in zeolitic frameworks.

    Science.gov (United States)

    Vitillo, Jenny G; Ricchiardi, Gabriele; Spoto, Giuseppe; Zecchina, Adriano

    2005-12-07

    Physisorption and encapsulation of molecular hydrogen in tailored microporous materials are two of the options for hydrogen storage. Among these materials, zeolites have been widely investigated. In these materials, the attained storage capacities vary widely with structure and composition, leading to the expectation that materials with improved binding sites, together with lighter frameworks, may represent efficient storage materials. In this work, we address the problem of the determination of the maximum amount of molecular hydrogen which could, in principle, be stored in a given zeolitic framework, as limited by the size, structure and flexibility of its pore system. To this end, the progressive filling with H2 of 12 purely siliceous models of common zeolite frameworks has been simulated by means of classical molecular mechanics. By monitoring the variation of cell parameters upon progressive filling of the pores, conclusions are drawn regarding the maximum storage capacity of each framework and, more generally, on framework flexibility. The flexible non-pentasils RHO, FAU, KFI, LTA and CHA display the highest maximal capacities, ranging between 2.86-2.65 mass%, well below the targets set for automotive applications but still in an interesting range. The predicted maximal storage capacities correlate well with experimental results obtained at low temperature. The technique is easily extendable to any other microporous structure, and it can provide a method for the screening of hypothetical new materials for hydrogen storage applications.

  8. Automatic physical inference with information maximizing neural networks

    Science.gov (United States)

    Charnock, Tom; Lavaux, Guilhem; Wandelt, Benjamin D.

    2018-04-01

    Compressing large data sets to a manageable number of summaries that are informative about the underlying parameters vastly simplifies both frequentist and Bayesian inference. When only simulations are available, these summaries are typically chosen heuristically, so they may inadvertently miss important information. We introduce a simulation-based machine learning technique that trains artificial neural networks to find nonlinear functionals of data that maximize Fisher information: information maximizing neural networks (IMNNs). In test cases where the posterior can be derived exactly, likelihood-free inference based on automatically derived IMNN summaries produces nearly exact posteriors, showing that these summaries are good approximations to sufficient statistics. In a series of numerical examples of increasing complexity and astrophysical relevance we show that IMNNs are robustly capable of automatically finding optimal, nonlinear summaries of the data even in cases where linear compression fails: inferring the variance of Gaussian signal in the presence of noise, inferring cosmological parameters from mock simulations of the Lyman-α forest in quasar spectra, and inferring frequency-domain parameters from LISA-like detections of gravitational waveforms. In this final case, the IMNN summary outperforms linear data compression by avoiding the introduction of spurious likelihood maxima. We anticipate that the automatic physical inference method described in this paper will be essential to obtain both accurate and precise cosmological parameter estimates from complex and large astronomical data sets, including those from LSST and Euclid.

  9. Entropy Maximization, Cutoff Distribution, and Finite Stellar Masses

    Directory of Open Access Journals (Sweden)

    Ritesh Kumar Dubey

    2008-01-01

    Full Text Available Conventional equilibrium statistical mechanics of open gravitational systems is known to be problematical. We first recall that spherical stars/galaxies acquire unbounded radii, become infinitely massive, and evaporate away continuously if one uses the standard Maxwellian distribution fB (which maximizes the usual Boltzmann-Shannon entropy and hence has a tail extending to infinity. Next, we show that these troubles disappear automatically if we employ the exact most probable distribution f (which maximizes the combinatorial entropy and hence possesses a sharp cutoff tail. Finally, if astronomical observation is carried out on a large galaxy, then the Poisson equation together with thermal de Broglie wavelength provides useful information about the cutoff radius rK, cutoff energy εK, and the huge quantum number K up to which the cluster exists. Thereby, a refinement over the empirical lowered isothermal King models, is achieved. Numerically, we find that the most probable distribution (MPD prediction fits well the number density profile near the outer edge of globular clusters.

  10. Quantum effects in non-maximally symmetric spaces

    International Nuclear Information System (INIS)

    Shen, T.C.

    1985-01-01

    Non-Maximally symmetric spaces provide a more general background to explore the relation between the geometry of the manifold and the quantum fields defined in the manifold than those with maximally symmetric spaces. A static Taub universe is used to study the effect of curvature anisotropy on the spontaneous symmetry breaking of a self-interacting scalar field. The one-loop effective potential on a λphi 4 field with arbitrary coupling xi is computed by zeta function regularization. For massless minimal coupled scalar fields, first order phase transitions can occur. Keeping the shape invariant but decreasing the curvature radius of the universe induces symmetry breaking. If the curvature radius is held constant, increasing deformation can restore the symmetry. Studies on the higher-dimensional Kaluza-Klein theories are also focused on the deformation effect. Using the dimensional regularization, the effective potential of the free scalar fields in M 4 x T/sup N/ and M 4 x (Taub) 3 spaces are obtained. The stability criterions for the static solutions of the self-consistent Einstein equations are derived. Stable solutions of the M 4 x S/sup N/ topology do not exist. With the Taub space as the internal space, the gauge coupling constants of SU(2), and U(1) can be determined geometrically. The weak angle is therefore predicted by geometry in this model

  11. A criterion to maximize the irreversible efficiency in heat engines

    CERN Document Server

    Aragon-Gonzalez, G; Leon-Galicia, A; Musharrafie-Martinez, M

    2003-01-01

    The purpose of this work is to obtain a more precise calculation of the effective limits to the efficiency, of several cyclic heat engines. This calculation is based, first, on the equations describing the irreversible efficiency, and second, on a method which results from a general criterion to maximize this efficiency, applicable to several heat engines. With this method, we apply the criterion to maximize efficiencies; establish lower and upper bounds, corresponding to the efficiencies of Curzon-Ahlborn-like and Carnot-like heat engines; and, finally, find analytical or numerical expressions for the efficiencies eta sub m sub e and eta sub m sub a sub x. eta sub m sub a sub x is the maximum irreversible efficiency; eta sub m sub e is the efficiency in which the irreversible efficiency achieves its maximum, in a similar way to the Curzon-Ahlborn efficiency (maximum work or power). The method was applied to a Brayton cycle, presenting internal dissipations of the working fluid and irreversibilities due to th...

  12. Scheduling sampling to maximize information about time dependence in experiments with limited resources

    DEFF Research Database (Denmark)

    Græsbøll, Kaare; Christiansen, Lasse Engbo

    2013-01-01

    Looking for periodicity in sampled data requires that periods (lags) of different length are represented in the sampling plan. We here present a method to assist in planning of temporal studies with sparse resources, which optimizes the number of observed time lags for a fixed amount of samples w...

  13. A Study to Maximize the Learning Experience in the Physical Chemistry Laboratory

    Science.gov (United States)

    1979-01-01

    predict whether or not corrosion will occur such as in the following problem: Would it be safe to store chlorine Cl^, in an aluminum container? Why...and chloroform. Plastic or aluminum foil covered vials may be used for storage containers. Loss due to evaporation should be avoided. The following...a standard procedure with antimony trichloride in chloroform to produce a blue color. The percent transmission of the incident filtered light for each

  14. Maximize a Team-Based Learning Gallery Walk Experience: Herding Cats Is Easier than You Think

    Science.gov (United States)

    Rodenbaugh, David W.

    2015-01-01

    Team-based learning (TBL) is an instructional strategy that promotes small group learning and peer instruction in a large class environment. TBL is structured to include the following steps: 1) student preparation, e.g., reading/reviewing course lectures, and 2) readiness assurance testing. Preparation and foundational knowledge is assessed on an…

  15. Increasing shot and data collection rates of the Shock/Shear experiment at the National Ignition Facility

    International Nuclear Information System (INIS)

    Doss, F. W.; Flippo, K. A.; Capelli, D.; Cardenas, T.; DeVolder, B.; Kline, J.; Kot, L.; Kurien, S.; Loomis, E.; Merritt, E. C.; Perry, T.; Schmidt, D.; Di Stefano, C.

    2016-01-01

    Updates to the Los Alamos laser-driven high-energy-density Shock/Shear mixing- layer experiment are reported, which have collectively increased the platform's shot and data acquisition rates. The strategies employed have included a move from two-strip to four-strip imagers (allowing four times to be recorded per shot instead of two), the implementation of physics-informed rules of engagements allowing for the maximum flexibility in a shot's total energy and symmetry performance, and splitting the laser's main drive pulse from a monolithic single pulse equal to all beams into a triply-segmented pulse which minimizes optics damage. (paper)

  16. Associations of maximal strength and muscular endurance test scores with cardiorespiratory fitness and body composition.

    Science.gov (United States)

    Vaara, Jani P; Kyröläinen, Heikki; Niemi, Jaakko; Ohrankämmen, Olli; Häkkinen, Arja; Kocay, Sheila; Häkkinen, Keijo

    2012-08-01

    The purpose of the present study was to assess the relationships between maximal strength and muscular endurance test scores additionally to previously widely studied measures of body composition and maximal aerobic capacity. 846 young men (25.5 ± 5.0 yrs) participated in the study. Maximal strength was measured using isometric bench press, leg extension and grip strength. Muscular endurance tests consisted of push-ups, sit-ups and repeated squats. An indirect graded cycle ergometer test was used to estimate maximal aerobic capacity (V(O2)max). Body composition was determined with bioelectrical impedance. Moreover, waist circumference (WC) and height were measured and body mass index (BMI) calculated. Maximal bench press was positively correlated with push-ups (r = 0.61, p strength (r = 0.34, p strength correlated positively (r = 0.36-0.44, p test scores were related to maximal aerobic capacity and body fat content, while fat free mass was associated with maximal strength test scores and thus is a major determinant for maximal strength. A contributive role of maximal strength to muscular endurance tests could be identified for the upper, but not the lower extremities. These findings suggest that push-up test is not only indicative of body fat content and maximal aerobic capacity but also maximal strength of upper body, whereas repeated squat test is mainly indicative of body fat content and maximal aerobic capacity, but not maximal strength of lower extremities.

  17. On an inverse source problem for enhanced oil recovery by wave motion maximization in reservoirs

    KAUST Repository

    Karve, Pranav M.

    2014-12-28

    © 2014, Springer International Publishing Switzerland. We discuss an optimization methodology for focusing wave energy to subterranean formations using strong motion actuators placed on the ground surface. The motivation stems from the desire to increase the mobility of otherwise entrapped oil. The goal is to arrive at the spatial and temporal description of surface sources that are capable of maximizing mobility in the target reservoir. The focusing problem is posed as an inverse source problem. The underlying wave propagation problems are abstracted in two spatial dimensions, and the semi-infinite extent of the physical domain is negotiated by a buffer of perfectly-matched-layers (PMLs) placed at the domain’s truncation boundary. We discuss two possible numerical implementations: Their utility for deciding the tempo-spatial characteristics of optimal wave sources is shown via numerical experiments. Overall, the simulations demonstrate the inverse source method’s ability to simultaneously optimize load locations and time signals leading to the maximization of energy delivery to a target formation.

  18. Data Assimilation in Air Contaminant Dispersion Using a Particle Filter and Expectation-Maximization Algorithm

    Directory of Open Access Journals (Sweden)

    Rongxiao Wang

    2017-09-01

    Full Text Available The accurate prediction of air contaminant dispersion is essential to air quality monitoring and the emergency management of contaminant gas leakage incidents in chemical industry parks. Conventional atmospheric dispersion models can seldom give accurate predictions due to inaccurate input parameters. In order to improve the prediction accuracy of dispersion models, two data assimilation methods (i.e., the typical particle filter & the combination of a particle filter and expectation-maximization algorithm are proposed to assimilate the virtual Unmanned Aerial Vehicle (UAV observations with measurement error into the atmospheric dispersion model. Two emission cases with different dimensions of state parameters are considered. To test the performances of the proposed methods, two numerical experiments corresponding to the two emission cases are designed and implemented. The results show that the particle filter can effectively estimate the model parameters and improve the accuracy of model predictions when the dimension of state parameters is relatively low. In contrast, when the dimension of state parameters becomes higher, the method of particle filter combining the expectation-maximization algorithm performs better in terms of the parameter estimation accuracy. Therefore, the proposed data assimilation methods are able to effectively support air quality monitoring and emergency management in chemical industry parks.

  19. Non-negative matrix factorization by maximizing correntropy for cancer clustering

    KAUST Repository

    Wang, Jim Jing-Yan

    2013-03-24

    Background: Non-negative matrix factorization (NMF) has been shown to be a powerful tool for clustering gene expression data, which are widely used to classify cancers. NMF aims to find two non-negative matrices whose product closely approximates the original matrix. Traditional NMF methods minimize either the l2 norm or the Kullback-Leibler distance between the product of the two matrices and the original matrix. Correntropy was recently shown to be an effective similarity measurement due to its stability to outliers or noise.Results: We propose a maximum correntropy criterion (MCC)-based NMF method (NMF-MCC) for gene expression data-based cancer clustering. Instead of minimizing the l2 norm or the Kullback-Leibler distance, NMF-MCC maximizes the correntropy between the product of the two matrices and the original matrix. The optimization problem can be solved by an expectation conditional maximization algorithm.Conclusions: Extensive experiments on six cancer benchmark sets demonstrate that the proposed method is significantly more accurate than the state-of-the-art methods in cancer clustering. 2013 Wang et al.; licensee BioMed Central Ltd.

  20. Data-Driven Engineering of Social Dynamics: Pattern Matching and Profit Maximization.

    Directory of Open Access Journals (Sweden)

    Huan-Kai Peng

    Full Text Available In this paper, we define a new problem related to social media, namely, the data-driven engineering of social dynamics. More precisely, given a set of observations from the past, we aim at finding the best short-term intervention that can lead to predefined long-term outcomes. Toward this end, we propose a general formulation that covers two useful engineering tasks as special cases, namely, pattern matching and profit maximization. By incorporating a deep learning model, we derive a solution using convex relaxation and quadratic-programming transformation. Moreover, we propose a data-driven evaluation method in place of the expensive field experiments. Using a Twitter dataset, we demonstrate the effectiveness of our dynamics engineering approach for both pattern matching and profit maximization, and study the multifaceted interplay among several important factors of dynamics engineering, such as solution validity, pattern-matching accuracy, and intervention cost. Finally, the method we propose is general enough to work with multi-dimensional time series, so it can potentially be used in many other applications.

  1. Influence maximization in social networks under an independent cascade-based model

    Science.gov (United States)

    Wang, Qiyao; Jin, Yuehui; Lin, Zhen; Cheng, Shiduan; Yang, Tan

    2016-02-01

    The rapid growth of online social networks is important for viral marketing. Influence maximization refers to the process of finding influential users who make the most of information or product adoption. An independent cascade-based model for influence maximization, called IMIC-OC, was proposed to calculate positive influence. We assumed that influential users spread positive opinions. At the beginning, users held positive or negative opinions as their initial opinions. When more users became involved in the discussions, users balanced their own opinions and those of their neighbors. The number of users who did not change positive opinions was used to determine positive influence. Corresponding influential users who had maximum positive influence were then obtained. Experiments were conducted on three real networks, namely, Facebook, HEP-PH and Epinions, to calculate maximum positive influence based on the IMIC-OC model and two other baseline methods. The proposed model resulted in larger positive influence, thus indicating better performance compared with the baseline methods.

  2. Non-negative matrix factorization by maximizing correntropy for cancer clustering.

    Science.gov (United States)

    Wang, Jim Jing-Yan; Wang, Xiaolei; Gao, Xin

    2013-03-24

    Non-negative matrix factorization (NMF) has been shown to be a powerful tool for clustering gene expression data, which are widely used to classify cancers. NMF aims to find two non-negative matrices whose product closely approximates the original matrix. Traditional NMF methods minimize either the l2 norm or the Kullback-Leibler distance between the product of the two matrices and the original matrix. Correntropy was recently shown to be an effective similarity measurement due to its stability to outliers or noise. We propose a maximum correntropy criterion (MCC)-based NMF method (NMF-MCC) for gene expression data-based cancer clustering. Instead of minimizing the l2 norm or the Kullback-Leibler distance, NMF-MCC maximizes the correntropy between the product of the two matrices and the original matrix. The optimization problem can be solved by an expectation conditional maximization algorithm. Extensive experiments on six cancer benchmark sets demonstrate that the proposed method is significantly more accurate than the state-of-the-art methods in cancer clustering.

  3. Maximizing the Potential of Internships in Gerontology and Geriatrics

    Science.gov (United States)

    Karasik, Rona J.

    2009-01-01

    Internships and similar applied opportunities have long been valued for providing students with opportunities for practical experience, career preparation, and personal growth. The need for applied experiences in gerontology and geriatrics is particularly salient. Creating and sustaining effective internship experiences, however, requires careful…

  4. Evaluation of processing technology for Triarrhena sacchariflora (Maxim. Nakai for ethanol production.

    Directory of Open Access Journals (Sweden)

    Fengqin Gao

    Full Text Available The effects of dilute H2SO4 concentration, forage:sulfuric acid ratio, digestion time, and digestion temperature were evaluated to determine effects on ethanol yield of Triarrhena sacchariflora (Maxim. Nakai. Twenty single factor experiments were conducted to evaluate H2SO4 concentration (0.5, 1.0, 1.5, 2.0, and 2.5%, w/w, forage:sulfuric acid ratio (1:6, 1:8, 1:10, 1:12, and 1:14, g/ml, digestion time (15, 30, 45, 60, and 90, min, digestion temperature (80, 100, 110, 120, and 125 °C for 3 replicates of the 5 levels of each factor. Based on results of the single factor experiments, an incomplete factorial was designed to evaluate ethanol yield from the best combinations of single factors. Finally, the best combination was tested by enzymatic hydrolysis and fermentation experiment in selected combinations according to pretreatment results. Percentage cellulose, hemicellulose, and lignin contents of forage residue after pretreatment, and glucose and xylose concentrations of the filtrate were analyzed prior to enzymatic hydrolysis, and percentage crystallinity was observed in untreated grass and pretreated residue. In addition, the solid residues were then hydrolysed and fermented by cellulase and yeast, the concentrations of glucose and ethanol being monitored for 96 h. Results showed that the order of the effect of main effect factors was as follows: digestion temperature > dilute H2SO4 concentration > digestion time > forage:sulfuric acid ratio. The best process parameters evaluated were sulfuric acid concentration of 1.5%, forage:sulfuric acid ratio of 1:6, digestion time of 15 min, and digestion temperature of 120°C. With this combination of factors, 80% of the cellulose was hydrolysed in 96 h, and 78% converted to ethanol. The findings identified that hemicelluloses were the key deconstruction barrier for pretreatment of Triarrhena sacchariflora (Maxim. Nakai for ethanol production. The results of this research provide evidence of

  5. Energetics of swimming at maximal speeds in humans.

    Science.gov (United States)

    Capelli, C; Pendergast, D R; Termin, B

    1998-10-01

    The energy cost per unit of distance (Cs, kilojoules per metre) of the front-crawl, back, breast and butterfly strokes was assessed in 20 elite swimmers. At sub-maximal speeds (v), Cs was measured dividing steady-state oxygen consumption (VO2) by the speed (v, metres per second). At supra-maximal v, Cs was calculated by dividing the total metabolic energy (E, kilojoules) spent in covering 45.7, 91.4 and 182.9 m by the distance. E was obtained as: E = Ean + alphaVO2maxtp - alphaVO2maxtau(1 - e(-(tp/tau))), where Ean was the amount of energy (kilojoules) derived from anaerobic sources, VO2max litres per second was the maximal oxygen uptake, alpha( = 20.9 kJ x 1 O2(-1)) was the energy equivalent of O2, tau (24 s) was the time constant assumed for the attainment of VO2max at muscle level at the onset of exercise, and tp (seconds) was the performance time. The lactic acid component was assumed to increase exponentially with tp to an asymptotic value of 0.418 kJ x kg(-1) of body mass for tp> or =120 s. The lactic acid component of Ean was obtained from the net increase of lactate concentration after exercise (delta[La]b) assuming that, when delta[La]b = 1 mmol x 1(-1) the net amount of metabolic energy released by lactate formation was 0.069 kJ x kg(-1). Over the entire range of v, front crawl was the least costly stroke. For example at 1 m x s(-1), Cs amounted, on average, to 0.70, 0.84, 0.82 and 0.124 kJ x m(-1) in front crawl, backstroke, butterfly and breaststroke, respectively; at 1.5 m x s(-1), Cs was 1.23, 1.47, 1.55 and 1.87 kJ x m(-1) in the four strokes, respectively. The Cs was a continuous function of the speed in all of the four strokes. It increased exponentially in crawl and backstroke, whereas in butterfly Cs attained a minimum at the two lowest v to increase exponentially at higher v. The Cs in breaststroke was a linear function of the v, probably because of the considerable amount of energy spent in this stroke for accelerating the body during the

  6. Open Maximal Mucosa-Sparing Functional Total Laryngectomy

    Directory of Open Access Journals (Sweden)

    Pavel Dulguerov

    2017-10-01

    Full Text Available BackgroundTotal laryngectomy after (chemoradiotherapy is associated with a high incidence of fistula and therefore flaps are advocated. The description of a transoral robotic total laryngectomy prompted us to develop similar minimally invasive open approaches for functional total laryngectomy.MethodsA retrospective study of consecutive unselected patients with a dysfunctional larynx after (chemoradiation that underwent open maximal mucosal-sparing functional total laryngectomy (MMSTL between 2014 and 2016 is presented. The surgical technique is described, and the complications and functional outcome are reviewed.ResultsThe cohorts included 10 patients who underwent open MMSTL. No pedicled flap was used. Only one postoperative fistula was noted (10%. All patients resumed oral diet and experienced a functional tracheo-esophageal voice.ConclusionMMSTL could be used to perform functional total laryngectomy without a robot and with minimal incidence of complications.

  7. Designing lattice structures with maximal nearest-neighbor entanglement

    International Nuclear Information System (INIS)

    Navarro-Munoz, J C; Lopez-Sandoval, R; Garcia, M E

    2009-01-01

    In this paper, we study the numerical optimization of nearest-neighbor concurrence of bipartite one- and two-dimensional lattices, as well as non-bipartite two-dimensional lattices. These systems are described in the framework of a tight-binding Hamiltonian while the optimization of concurrence was performed using genetic algorithms. Our results show that the concurrence of the optimized lattice structures is considerably higher than that of non-optimized systems. In the case of one-dimensional chains, the concurrence increases dramatically when the system begins to dimerize, i.e., it undergoes a structural phase transition (Peierls distortion). This result is consistent with the idea that entanglement is maximal or shows a singularity near quantum phase transitions. Moreover, the optimization of concurrence in two-dimensional bipartite and non-bipartite lattices is achieved when the structures break into smaller subsystems, which are arranged in geometrically distinguishable configurations.

  8. The spinor heat kernel in maximally symmetric spaces

    International Nuclear Information System (INIS)

    Camporesi, R.

    1992-01-01

    The heat kernel K(x, x', t) of the iterated Dirac operator on an N-dimensional simply connected maximally symmetric Riemannian manifold is calculated. On the odd-dimensional hyperbolic spaces K is a Minakshisundaram-DeWitt expansion which terminates to the coefficient a (N-1)/2 and is exact. On the odd spheres the heat kernel may be written as an image sum of WKB kernels, each term corresponding to a classical path (geodesic). In the even dimensional case the WKB approximation is not exact, but a closed form of K is derived both in terms of (spherical) eigenfunctions and of a 'sum over classical paths'. The spinor Plancherel measure μ(λ) and ζ function in the hyperbolic case are also calculated. A simple relation between the analytic structure of μ on H N and the degeneracies of the Dirac operator on S N is found. (orig.)

  9. Low-energy restoration of parity and maximal symmetry

    International Nuclear Information System (INIS)

    Raychaudhuri, A.; Sarkar, U.

    1982-01-01

    The maximal symmetry of fermions of one generation, SU(16), which includes the left-right-symmetric Pati-Salam group, SU(4)/sub c/ x SU(2) /sub L/ x SU(2)/sub R/, as a subgroup, allows the possibility of a low-energy (M/sub R/approx.100 GeV) breaking of the left-right symmetry. It is known that such a low-energy restoration of parity can be consistent with weak-interaction phenomenology. We examine different chains of descent of SU(16) that admit a low value of M/sub R/ and determine the other intermediate symmetry-breaking mass scales associated with each of these chains. These additional mass scales provide an alternative to the ''great desert'' expected in some grand unifying models. The contributions of the Higgs fields in the renormalization-group equations are retained and are found to be important

  10. The price of anarchy is maximized at the percolation threshold

    Science.gov (United States)

    Skinner, Brian

    2015-03-01

    When many independent users try to route traffic through a network, the flow can easily become suboptimal as a consequence of congestion of the most efficient paths. The degree of this suboptimality is quantified by the so-called ``price of anarchy'' (POA), but so far there are no general rules for when to expect a large POA in a random network. Here I address this question by introducing a simple model of flow through a network with randomly-placed ``congestible'' and ``incongestible'' links. I show that the POA is maximized precisely when the fraction of congestible links matches the percolation threshold of the lattice. Both the POA and the total cost demonstrate critical scaling near the percolation threshold.

  11. Price of anarchy is maximized at the percolation threshold

    Science.gov (United States)

    Skinner, Brian

    2015-05-01

    When many independent users try to route traffic through a network, the flow can easily become suboptimal as a consequence of congestion of the most efficient paths. The degree of this suboptimality is quantified by the so-called price of anarchy (POA), but so far there are no general rules for when to expect a large POA in a random network. Here I address this question by introducing a simple model of flow through a network with randomly placed congestible and incongestible links. I show that the POA is maximized precisely when the fraction of congestible links matches the percolation threshold of the lattice. Both the POA and the total cost demonstrate critical scaling near the percolation threshold.

  12. Price of anarchy is maximized at the percolation threshold

    Energy Technology Data Exchange (ETDEWEB)

    Skinner, Brian

    2015-05-01

    When many independent users try to route traffic through a network, the flow can easily become suboptimal as a consequence of congestion of the most efficient paths. The degree of this suboptimality is quantified by the so-called \\price of anarchy" (POA), but so far there are no general rules for when to expect a large POA in a random network. Here I address this question by introducing a simple model of flow through a network with randomly-placed "congestible" and "incongestible" links. I show that the POA is maximized precisely when the fraction of congestible links matches the percolation threshold of the lattice. Further, for large networks the value of the POA appears to saturate at its theoretical maximum value.

  13. Price of anarchy is maximized at the percolation threshold.

    Science.gov (United States)

    Skinner, Brian

    2015-05-01

    When many independent users try to route traffic through a network, the flow can easily become suboptimal as a consequence of congestion of the most efficient paths. The degree of this suboptimality is quantified by the so-called price of anarchy (POA), but so far there are no general rules for when to expect a large POA in a random network. Here I address this question by introducing a simple model of flow through a network with randomly placed congestible and incongestible links. I show that the POA is maximized precisely when the fraction of congestible links matches the percolation threshold of the lattice. Both the POA and the total cost demonstrate critical scaling near the percolation threshold.

  14. Maximization of fructose esters synthesis by response surface methodology.

    Science.gov (United States)

    Neta, Nair Sampaio; Peres, António M; Teixeira, José A; Rodrigues, Ligia R

    2011-07-01

    Enzymatic synthesis of fructose fatty acid ester was performed in organic solvent media, using a purified lipase from Candida antartica B immobilized in acrylic resin. Response surface methodology with a central composite rotatable design based on five levels was implemented to optimize three experimental operating conditions (temperature, agitation and reaction time). A statistical significant cubic model was established. Temperature and reaction time were found to be the most significant parameters. The optimum operational conditions for maximizing the synthesis of fructose esters were 57.1°C, 100 rpm and 37.8 h. The model was validated in the identified optimal conditions to check its adequacy and accuracy, and an experimental esterification percentage of 88.4% (±0.3%) was obtained. These results showed that an improvement of the enzymatic synthesis of fructose esters was obtained under the optimized conditions. Copyright © 2011 Elsevier B.V. All rights reserved.

  15. The globalization of ayahuasca: harm reduction or benefit maximization?

    Science.gov (United States)

    Tupper, Kenneth W

    2008-08-01

    Ayahuasca is a tea made from two plants native to the Amazon, Banisteriopsis caapi and Psychotria viridis, which, respectively, contain the psychoactive chemicals harmala alkaloids and dimethyltryptamine. The tea has been used by indigenous peoples in countries such as Brazil, Ecuador and Peru for medicinal, spiritual and cultural purposes since pre-Columbian times. In the 20th century, ayahuasca spread beyond its native habitat and has been incorporated into syncretistic practices that are being adopted by non-indigenous peoples in modern Western contexts. Ayahuasca's globalization in the past few decades has led to a number of legal cases which pit religious freedom against national drug control laws. This paper explores some of the philosophical and policy implications of contemporary ayahuasca use. It addresses the issue of the social construction of ayahuasca as a medicine, a sacrament and a "plant teacher." Issues of harm reduction with respect to ayahuasca use are explored, but so too is the corollary notion of "benefit maximization."

  16. Discussion on: "Profit Maximization of a Power Plant"

    DEFF Research Database (Denmark)

    Boomsma (fhv. Kristoffersen), Trine Krogh; Fleten, Stein-Erik

    2012-01-01

    that the research may have been done at some distance to the reality of power operations. As opposed to formulating the tracking as a hard constraint, the authors penalize volume deviations between reference and actual production (tracking error) in the objective function. This is not entirely consistent......Kragelund et al. provides an interesting contribution to operations scheduling in liberalized electricity markets. They address the problem of profit maximization for a power plant participating in the electricity market. In particular, given that the plant has already been dispatched in a day......-ahead market, the aim is to schedule production throughout an operation day while complying with the day-ahead commitments, referred to in the paper as tracking a predefined production reference. The authors refer to Fig. 2 for an example of a production reference plan for a power plant of DONG Energy. A minor...

  17. Designing lattice structures with maximal nearest-neighbor entanglement

    Energy Technology Data Exchange (ETDEWEB)

    Navarro-Munoz, J C; Lopez-Sandoval, R [Instituto Potosino de Investigacion CientIfica y Tecnologica, Camino a la presa San Jose 2055, 78216 San Luis Potosi (Mexico); Garcia, M E [Theoretische Physik, FB 18, Universitaet Kassel and Center for Interdisciplinary Nanostructure Science and Technology (CINSaT), Heinrich-Plett-Str.40, 34132 Kassel (Germany)

    2009-08-07

    In this paper, we study the numerical optimization of nearest-neighbor concurrence of bipartite one- and two-dimensional lattices, as well as non-bipartite two-dimensional lattices. These systems are described in the framework of a tight-binding Hamiltonian while the optimization of concurrence was performed using genetic algorithms. Our results show that the concurrence of the optimized lattice structures is considerably higher than that of non-optimized systems. In the case of one-dimensional chains, the concurrence increases dramatically when the system begins to dimerize, i.e., it undergoes a structural phase transition (Peierls distortion). This result is consistent with the idea that entanglement is maximal or shows a singularity near quantum phase transitions. Moreover, the optimization of concurrence in two-dimensional bipartite and non-bipartite lattices is achieved when the structures break into smaller subsystems, which are arranged in geometrically distinguishable configurations.

  18. Decade of the Brain 1990--2000: Maximizing human potential

    Energy Technology Data Exchange (ETDEWEB)

    1991-04-01

    The US Decade of the Brain offers scientists throughout the Federal Government a unique opportunity to advance and apply scientific knowledge about the brain and nervous system. During the next 10 years, scientists hope to maximize human potential through studies of human behavior, senses and communication, learning and memory, genetic/chemical alterations, and environmental interactions. Progress in these areas should lead to reductions in mortality from brain and nervous system disorders and to improvements in the quality of life. This report identifies nine research areas that could form the basis of an integrated program in the brain and behavioral sciences. A chart summarizing the Federal activities in these nine areas may be found at the back of the report. In addition, three areas that span the nine research areas -- basic research, technology and international activities -- are considered.

  19. Maximizing entropy of image models for 2-D constrained coding

    DEFF Research Database (Denmark)

    Forchhammer, Søren; Danieli, Matteo; Burini, Nino

    2010-01-01

    This paper considers estimating and maximizing the entropy of two-dimensional (2-D) fields with application to 2-D constrained coding. We consider Markov random fields (MRF), which have a non-causal description, and the special case of Pickard random fields (PRF). The PRF are 2-D causal finite...... context models, which define stationary probability distributions on finite rectangles and thus allow for calculation of the entropy. We consider two binary constraints and revisit the hard square constraint given by forbidding neighboring 1s and provide novel results for the constraint that no uniform 2...... £ 2 squares contains all 0s or all 1s. The maximum values of the entropy for the constraints are estimated and binary PRF satisfying the constraint are characterized and optimized w.r.t. the entropy. The maximum binary PRF entropy is 0.839 bits/symbol for the no uniform squares constraint. The entropy...

  20. General spectral flow formula for fixed maximal domain

    DEFF Research Database (Denmark)

    Booss-Bavnbek, Bernhelm; Zhu, Chaofeng

    2005-01-01

    of the resulting continuous family of (unbounded) self-adjoint Fredholm operators in terms of the Maslov index of two related curves of Lagrangian spaces. One curve is given by the varying domains, the other by the Cauchy data spaces. We provide rigorous definitions of the underlying concepts of spectral theory......We consider a continuous curve of linear elliptic formally self-adjoint differential operators of first order with smooth coefficients over a compact Riemannian manifold with boundary together with a continuous curve of global elliptic boundary value problems. We express the spectral flow...... and symplectic analysis and give a full (and surprisingly short) proof of our General Spectral Flow Formula for the case of fixed maximal domain. As a side result, we establish local stability of weak inner unique continuation property (UCP) and explain its role for parameter dependent spectral theory....

  1. Long memory analysis by using maximal overlapping discrete wavelet transform

    Science.gov (United States)

    Shafie, Nur Amalina binti; Ismail, Mohd Tahir; Isa, Zaidi

    2015-05-01

    Long memory process is the asymptotic decay of the autocorrelation or spectral density around zero. The main objective of this paper is to do a long memory analysis by using the Maximal Overlapping Discrete Wavelet Transform (MODWT) based on wavelet variance. In doing so, stock market of Malaysia, China, Singapore, Japan and United States of America are used. The risk of long term and short term investment are also being looked into. MODWT can be analyzed with time domain and frequency domain simultaneously and decomposing wavelet variance to different scales without loss any information. All countries under studied show that they have long memory. Subprime mortgage crisis in 2007 is occurred in the United States of America are possible affect to the major trading countries. Short term investment is more risky than long term investment.

  2. Maximizing Information from Residential Measurements of Volatile Organic Compounds

    Energy Technology Data Exchange (ETDEWEB)

    Maddalena, Randy [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Li, Na [Berkeley Analytical Associates, Richmond, CA (United States); Hodgson, Alfred [Berkeley Analytical Associates, Richmond, CA (United States); Offermann, Francis [Indoor Environmental Engineering, San Francisco, CA (United States); Singer, Brett [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2013-02-01

    Continually changing materials used in home construction and finishing can introduce new chemicals or changes in the VOC profile in residential air and the trend towards tighter homes can lead to higher exposure concentrations for many indoor sources. However, the complex mixture of VOCs in residential air makes it difficult to discover emerging contaminants and/or trends in pollutant profiles. The purpose of this study is to prepare a comprehensive library of chemicals found in homes, along with a semi-quantitative approach to maximize the information gained from VOC measurements. We carefully reviewed data from 108 new California homes and identified 238 individual compounds. The majority of the identified VOCs originated indoors. Only 31% were found to have relevant health based exposure guidelines and less than 10% had a chronic reference exposure level (CREL). The finding highlights the importance of extending IAQ studies to include a wider range of VOCs

  3. Maximizing sparse matrix vector product performance in MIMD computers

    Energy Technology Data Exchange (ETDEWEB)

    McLay, R.T.; Kohli, H.S.; Swift, S.L.; Carey, G.F.

    1994-12-31

    A considerable component of the computational effort involved in conjugate gradient solution of structured sparse matrix systems is expended during the Matrix-Vector Product (MVP), and hence it is the focus of most efforts at improving performance. Such efforts are hindered on MIMD machines due to constraints on memory, cache and speed of memory-cpu data transfer. This paper describes a strategy for maximizing the performance of the local computations associated with the MVP. The method focuses on single stride memory access, and the efficient use of cache by pre-loading it with data that is re-used while bypassing it for other data. The algorithm is designed to behave optimally for varying grid sizes and number of unknowns per gridpoint. Results from an assembly language implementation of the strategy on the iPSC/860 show a significant improvement over the performance using FORTRAN.

  4. Pareto optimization of an industrial ecosystem: sustainability maximization

    Directory of Open Access Journals (Sweden)

    J. G. M.-S. Monteiro

    2010-09-01

    Full Text Available This work investigates a procedure to design an Industrial Ecosystem for sequestrating CO2 and consuming glycerol in a Chemical Complex with 15 integrated processes. The Complex is responsible for the production of methanol, ethylene oxide, ammonia, urea, dimethyl carbonate, ethylene glycol, glycerol carbonate, β-carotene, 1,2-propanediol and olefins, and is simulated using UNISIM Design (Honeywell. The process environmental impact (EI is calculated using the Waste Reduction Algorithm, while Profit (P is estimated using classic cost correlations. MATLAB (The Mathworks Inc is connected to UNISIM to enable optimization. The objective is granting maximum process sustainability, which involves finding a compromise between high profitability and low environmental impact. Sustainability maximization is therefore understood as a multi-criteria optimization problem, addressed by means of the Pareto optimization methodology for trading off P vs. EI.

  5. Tetrahedral meshing via maximal Poisson-disk sampling

    KAUST Repository

    Guo, Jianwei

    2016-02-15

    In this paper, we propose a simple yet effective method to generate 3D-conforming tetrahedral meshes from closed 2-manifold surfaces. Our approach is inspired by recent work on maximal Poisson-disk sampling (MPS), which can generate well-distributed point sets in arbitrary domains. We first perform MPS on the boundary of the input domain, we then sample the interior of the domain, and we finally extract the tetrahedral mesh from the samples by using 3D Delaunay or regular triangulation for uniform or adaptive sampling, respectively. We also propose an efficient optimization strategy to protect the domain boundaries and to remove slivers to improve the meshing quality. We present various experimental results to illustrate the efficiency and the robustness of our proposed approach. We demonstrate that the performance and quality (e.g., minimal dihedral angle) of our approach are superior to current state-of-the-art optimization-based approaches.

  6. Optimal weight based on energy imbalance and utility maximization

    Science.gov (United States)

    Sun, Ruoyan

    2016-01-01

    This paper investigates the optimal weight for both male and female using energy imbalance and utility maximization. Based on the difference of energy intake and expenditure, we develop a state equation that reveals the weight gain from this energy gap. We ​construct an objective function considering food consumption, eating habits and survival rate to measure utility. Through applying mathematical tools from optimal control methods and qualitative theory of differential equations, we obtain some results. For both male and female, the optimal weight is larger than the physiologically optimal weight calculated by the Body Mass Index (BMI). We also study the corresponding trajectories to steady state weight respectively. Depending on the value of a few parameters, the steady state can either be a saddle point with a monotonic trajectory or a focus with dampened oscillations.

  7. Techniques to maximize software reliability in radiation fields

    International Nuclear Information System (INIS)

    Eichhorn, G.; Piercey, R.B.

    1986-01-01

    Microprocessor system failures due to memory corruption by single event upsets (SEUs) and/or latch-up in RAM or ROM memory are common in environments where there is high radiation flux. Traditional methods to harden microcomputer systems against SEUs and memory latch-up have usually involved expensive large scale hardware redundancy. Such systems offer higher reliability, but they tend to be more complex and non-standard. At the Space Astronomy Laboratory the authors have developed general programming techniques for producing software which is resistant to such memory failures. These techniques, which may be applied to standard off-the-shelf hardware, as well as custom designs, include an implementation of Maximally Redundant Software (MRS) model, error detection algorithms and memory verification and management

  8. Maximal Abelian gauge and a generalized BRST transformation

    Directory of Open Access Journals (Sweden)

    Shinichi Deguchi

    2016-05-01

    Full Text Available We apply a generalized Becchi–Rouet–Stora–Tyutin (BRST formulation to establish a connection between the gauge-fixed SU(2 Yang–Mills (YM theories formulated in the Lorenz gauge and in the Maximal Abelian (MA gauge. It is shown that the generating functional corresponding to the Faddeev–Popov (FP effective action in the MA gauge can be obtained from that in the Lorenz gauge by carrying out an appropriate finite and field-dependent BRST (FFBRST transformation. In this procedure, the FP effective action in the MA gauge is found from that in the Lorenz gauge by incorporating the contribution of non-trivial Jacobian due to the FFBRST transformation of the path integral measure. The present FFBRST formulation might be useful to see how Abelian dominance in the MA gauge is realized in the Lorenz gauge.

  9. Short Run Profit Maximization in a Convex Analysis Framework

    Directory of Open Access Journals (Sweden)

    Ilko Vrankic

    2017-03-01

    Full Text Available In this article we analyse the short run profit maximization problem in a convex analysis framework. The goal is to apply the results of convex analysis due to unique structure of microeconomic phenomena on the known short run profit maximization problem where the results from convex analysis are deductively applied. In the primal optimization model the technology in the short run is represented by the short run production function and the normalized profit function, which expresses profit in the output units, is derived. In this approach the choice variable is the labour quantity. Alternatively, technology is represented by the real variable cost function, where costs are expressed in the labour units, and the normalized profit function is derived, this time expressing profit in the labour units. The choice variable in this approach is the quantity of production. The emphasis in these two perspectives of the primal approach is given to the first order necessary conditions of both models which are the consequence of enveloping the closed convex set describing technology with its tangents. The dual model includes starting from the normalized profit function and recovering the production function, and alternatively the real variable cost function. In the first perspective of the dual approach the choice variable is the real wage, and in the second it is the real product price expressed in the labour units. It is shown that the change of variables into parameters and parameters into variables leads to both optimization models which give the same system of labour demand and product supply functions and their inverses. By deductively applying the results of convex analysis the comparative statics results are derived describing the firm's behaviour in the short run.

  10. Expectation-Maximization Binary Clustering for Behavioural Annotation.

    Science.gov (United States)

    Garriga, Joan; Palmer, John R B; Oltra, Aitana; Bartumeus, Frederic

    2016-01-01

    The growing capacity to process and store animal tracks has spurred the development of new methods to segment animal trajectories into elementary units of movement. Key challenges for movement trajectory segmentation are to (i) minimize the need of supervision, (ii) reduce computational costs, (iii) minimize the need of prior assumptions (e.g. simple parametrizations), and (iv) capture biologically meaningful semantics, useful across a broad range of species. We introduce the Expectation-Maximization binary Clustering (EMbC), a general purpose, unsupervised approach to multivariate data clustering. The EMbC is a variant of the Expectation-Maximization Clustering (EMC), a clustering algorithm based on the maximum likelihood estimation of a Gaussian mixture model. This is an iterative algorithm with a closed form step solution and hence a reasonable computational cost. The method looks for a good compromise between statistical soundness and ease and generality of use (by minimizing prior assumptions and favouring the semantic interpretation of the final clustering). Here we focus on the suitability of the EMbC algorithm for behavioural annotation of movement data. We show and discuss the EMbC outputs in both simulated trajectories and empirical movement trajectories including different species and different tracking methodologies. We use synthetic trajectories to assess the performance of EMbC compared to classic EMC and Hidden Markov Models. Empirical trajectories allow us to explore the robustness of the EMbC to data loss and data inaccuracies, and assess the relationship between EMbC output and expert label assignments. Additionally, we suggest a smoothing procedure to account for temporal correlations among labels, and a proper visualization of the output for movement trajectories. Our algorithm is available as an R-package with a set of complementary functions to ease the analysis.

  11. Expectation-Maximization Binary Clustering for Behavioural Annotation.

    Directory of Open Access Journals (Sweden)

    Joan Garriga

    Full Text Available The growing capacity to process and store animal tracks has spurred the development of new methods to segment animal trajectories into elementary units of movement. Key challenges for movement trajectory segmentation are to (i minimize the need of supervision, (ii reduce computational costs, (iii minimize the need of prior assumptions (e.g. simple parametrizations, and (iv capture biologically meaningful semantics, useful across a broad range of species. We introduce the Expectation-Maximization binary Clustering (EMbC, a general purpose, unsupervised approach to multivariate data clustering. The EMbC is a variant of the Expectation-Maximization Clustering (EMC, a clustering algorithm based on the maximum likelihood estimation of a Gaussian mixture model. This is an iterative algorithm with a closed form step solution and hence a reasonable computational cost. The method looks for a good compromise between statistical soundness and ease and generality of use (by minimizing prior assumptions and favouring the semantic interpretation of the final clustering. Here we focus on the suitability of the EMbC algorithm for behavioural annotation of movement data. We show and discuss the EMbC outputs in both simulated trajectories and empirical movement trajectories including different species and different tracking methodologies. We use synthetic trajectories to assess the performance of EMbC compared to classic EMC and Hidden Markov Models. Empirical trajectories allow us to explore the robustness of the EMbC to data loss and data inaccuracies, and assess the relationship between EMbC output and expert label assignments. Additionally, we suggest a smoothing procedure to account for temporal correlations among labels, and a proper visualization of the output for movement trajectories. Our algorithm is available as an R-package with a set of complementary functions to ease the analysis.

  12. Maximal Oxygen Consumption is Reduced in Aquaporin-1 Knockout Mice

    Directory of Open Access Journals (Sweden)

    Samer Al-Samir

    2016-08-01

    Full Text Available We have measured maximal oxygen consumption (V’O2,max of mice lacking one or two of the established mouse red-cell CO2 channels AQP1, AQP9 and Rhag. We intended to study whether these proteins, by acting as channels for O2, determine O2 exchange in the lung and in the periphery. We found that V’O2,max as determined by the Helox technique is reduced by ~ 16%, when AQP1 is knocked out, but not when AQP9 or Rhag are lacking. This figure holds for animals respiring normoxic as well as hypoxic gas mixtures. To see whether the reduction of V’O2,max is due to impaired O2 uptake in the lung, we measured carotid arterial O2 saturation (SO2 by pulse oximetry. Neither under normoxic (inspiratory O2 21% nor under hypoxic conditions (11% O2 is there a difference in SO2 between AQP1null and WT mice, suggesting that AQP1 is not critical for O2 uptake in the lung. The fact that the % reduction of V’O2,max is identical in normoxia and hypoxia indicates moreover that the limitation of V’O2,max is not due to an O2 diffusion problem, neither in the lung nor in the periphery. Instead, it appears likely that AQP1null animals exhibit a reduced V’O2,max due to the reduced wall thickness and muscle mass of the left ventricles of their hearts, as reported previously. We conclude that very likely the properties of the hearts of AQP1 knockout mice cause a reduced maximal cardiac output and thus cause a reduced V’O2,max, which constitutes a new phenotype of these mice.

  13. Global haplotype partitioning for maximal associated SNP pairs.

    Science.gov (United States)

    Katanforoush, Ali; Sadeghi, Mehdi; Pezeshk, Hamid; Elahi, Elahe

    2009-08-27

    Global partitioning based on pairwise associations of SNPs has not previously been used to define haplotype blocks within genomes. Here, we define an association index based on LD between SNP pairs. We use the Fisher's exact test to assess the statistical significance of the LD estimator. By this test, each SNP pair is characterized as associated, independent, or not-statistically-significant. We set limits on the maximum acceptable proportion of independent pairs within all blocks and search for the partitioning with maximal proportion of associated SNP pairs. Essentially, this model is reduced to a constrained optimization problem, the solution of which is obtained by iterating a dynamic programming algorithm. In comparison with other methods, our algorithm reports blocks of larger average size. Nevertheless, the haplotype diversity within the blocks is captured by a small number of tagSNPs. Resampling HapMap haplotypes under a block-based model of recombination showed that our algorithm is robust in reproducing the same partitioning for recombinant samples. Our algorithm performed better than previously reported models in a case-control association study aimed at mapping a single locus trait, based on simulation results that were evaluated by a block-based statistical test. Compared to methods of haplotype block partitioning, we performed best on detection of recombination hotspots. Our proposed method divides chromosomes into the regions within which allelic associations of SNP pairs are maximized. This approach presents a native design for dimension reduction in genome-wide association studies. Our results show that the pairwise allelic association of SNPs can describe various features of genomic variation, in particular recombination hotspots.

  14. Global haplotype partitioning for maximal associated SNP pairs

    Directory of Open Access Journals (Sweden)

    Pezeshk Hamid

    2009-08-01

    Full Text Available Abstract Background Global partitioning based on pairwise associations of SNPs has not previously been used to define haplotype blocks within genomes. Here, we define an association index based on LD between SNP pairs. We use the Fisher's exact test to assess the statistical significance of the LD estimator. By this test, each SNP pair is characterized as associated, independent, or not-statistically-significant. We set limits on the maximum acceptable proportion of independent pairs within all blocks and search for the partitioning with maximal proportion of associated SNP pairs. Essentially, this model is reduced to a constrained optimization problem, the solution of which is obtained by iterating a dynamic programming algorithm. Results In comparison with other methods, our algorithm reports blocks of larger average size. Nevertheless, the haplotype diversity within the blocks is captured by a small number of tagSNPs. Resampling HapMap haplotypes under a block-based model of recombination showed that our algorithm is robust in reproducing the same partitioning for recombinant samples. Our algorithm performed better than previously reported models in a case-control association study aimed at mapping a single locus trait, based on simulation results that were evaluated by a block-based statistical test. Compared to methods of haplotype block partitioning, we performed best on detection of recombination hotspots. Conclusion Our proposed method divides chromosomes into the regions within which allelic associations of SNP pairs are maximized. This approach presents a native design for dimension reduction in genome-wide association studies. Our results show that the pairwise allelic association of SNPs can describe various features of genomic variation, in particular recombination hotspots.

  15. Comparison of three protocols for measuring the maximal respiratory pressures

    Directory of Open Access Journals (Sweden)

    Isabela Maria B. Sclauser Pessoa

    Full Text Available Introduction To avoid the selection of submaximal efforts during the assessment of maximal inspiratory and expiratory pressures (MIP and MEP, some reproducibility criteria have been suggested. Criteria that stand out are those proposed by the American Thoracic Society (ATS and European Respiratory Society (ERS and by the Brazilian Thoracic Association (BTA. However, no studies were found that compared these criteria or assessed the combination of both protocols. Objectives To assess the pressure values selected and the number of maneuvers required to achieve maximum performance using the reproducibility criteria proposed by the ATS/ERS, the BTA and the present study. Materials and method 113 healthy subjects (43.04 ± 16.94 years from both genders were assessed according to the criteria proposed by the ATS/ERS, BTA and the present study. Descriptive statistics were used for analysis, followed by ANOVA for repeated measures and post hoc LSD or by Friedman test and post hoc Wilcoxon, according to the data distribution. Results The criterion proposed by the present study resulted in a significantly higher number of maneuvers (MIP and MEP – median and 25%-75% interquartile range: 5[5-6], 4[3-5] and 3[3-4] for the present study criterion, BTA and ATS/ERS, respectively; p < 0.01 and higher pressure values (MIP – mean and 95% confidence interval: 103[91.43-103.72], 100[97.19-108.83] and 97.6[94.06-105.95]; MEP: median and 25%-75% interquartile range: 124.2[101.4-165.9], 123.3[95.4-153.8] and 118.4[95.5-152.7]; p < 0.05. Conclusion The proposed criterion resulted in the selection of pressure values closer to the individual’s maximal capacity. This new criterion should be considered in future studies concerning MIP and MEP measurements.

  16. Two-microphone separation of speech mixtures based on interclass variance maximization.

    Science.gov (United States)

    Cobos, Maximo; Lopez, Jose J

    2010-03-01

    Sparse methods for speech separation have become a discussed issue in acoustic signal processing. These sparse methods provide a powerful approach to the separation of several signals in the underdetermined case, i.e., when there are more sources than sensors. In this paper, a two-microphone separation method is presented. The proposed algorithm is based on grouping time-frequency points with similar direction-of-arrival (DOA) using a multi-level thresholding approach. The thresholds are calculated via the maximization of the interclass variance between DOA estimates and allow to identify angular sections, wherein the speakers are located with a strong likelihood. These sections define a set of time-frequency masks that are able to separate several sound sources in realistic scenarios and with little computational cost. Several experiments carried out under different mixing situations are discussed, showing the validity of the proposed approach.

  17. Clock hypothesis of relativity theory, maximal acceleration, and Mössbauer spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Potzel, W., E-mail: wpotzel@ph.tum.de [Technische Universität München, Physik-Department E15 (Germany)

    2016-12-15

    Results obtained several years ago using the high-resolution 93.3 keV Mössbauer resonance in {sup 67}ZnO and β{sup ′}-brass have been reanalyzed with the notion that the clock hypothesis of Special Relativity Theory is not sufficient, but that a maximal acceleration a{sub m} exists and that an acceleration a contributes to the temperature dependence of the center shift by a term ±(1/2)(a/a{sub m}){sup 2}. The significance of the sign of this term is discussed in detail. For both substances a lower limit of a{sub m}>1.5⋅10{sup 21}m/s {sup 2} is inferred which is more than two orders of magnitude larger than - and thus excludes - the value a{sub m}=1⋅10{sup 19}m/s {sup 2} suggested by {sup 57}Fe rotor experiments.

  18. Baryogenesis, dark matter and the maximal temperature of the early universe

    Energy Technology Data Exchange (ETDEWEB)

    Buchmueller, Wilfried

    2012-12-15

    Mechanisms for the generation of the matter-antimatter asymmetry and dark matter strongly depend on the reheating temperature T{sub R}, the maximal temperature reached in the early universe. Forthcoming results from the LHC, low energy experiments, astrophysical observations and the Planck satellite will significantly constrain baryogenesis and the nature of dark matter, and thereby provide valuable information about the very early hot universe. At present, a wide range of reheating temperatures is still consistent with observations. We illustrate possible origins of matter and dark matter with four examples: moduli decay, electroweak baryogenesis, leptogenesis in the {nu}MSM and thermal leptogenesis. Finally, we discuss the connection between baryogenesis, dark matter and inflation in the context of supersymmetric spontaneous B-L breaking.

  19. A High Performance Target Tracing Transmission Model Oriented to Lifecycle Maximization

    Directory of Open Access Journals (Sweden)

    Zhong-Nan Zhao

    2016-01-01

    Full Text Available For the high speed sensor networks applications such as Internet of Things, multimedia transmission, the realization of high-rate transmission under limited resources has become a problem to be solved. A high speed transmission and energy optimization model oriented to lifecycle maximization is proposed in this paper. Based on information-directed mechanism, the energy threshold set and the relay node distance selection will be done in the process of target tracing, as a result, retaining a balance between transmission rate and energy consumption. Meanwhile, multiagent coevolution is adopted to achieve the maximum of network lifecycle. Comparing with the relevant methods, indexes for network such as hops, throughput, and number of active nodes, standard deviation of remaining energy, and the network lifecycle are considered, and the simulated experiments show that the proposed method will promote the transmission rate effectively, prolong the network lifecycle, and improve network performance as a whole.

  20. Evaluating Simulation Methodologies to Determine Best Strategies to Maximize Student Learning.

    Science.gov (United States)

    Scherer, Yvonne K; Foltz-Ramos, Kelly; Fabry, Donna; Chao, Ying-Yu

    2016-01-01

    Limited evidence exists as to the most effective ways to provide simulation experiences to maximize student learning. This quasi-experimental study investigated 2 different strategies repeated versus 1 exposure and participation versus observation on student outcomes following exposure to a high-fidelity acute asthma exacerbation of asthma scenario. Immediate repeated exposure resulted in significantly higher scores on knowledge, student satisfaction and self-confidence, and clinical performance measures than a single exposure. Significant intergroup differences were found on participants' satisfaction and self-confidence as compared with observers. Implications for nurse educators include expanding the observer role when designing repeated exposure to simulations and integrating technical, cognitive, and behavioral outcomes as a way for faculty to evaluate students' clinical performance. Published by Elsevier Inc.

  1. Maximization of wave motion within a hydrocarbon reservoir for wave-based enhanced oil recovery

    KAUST Repository

    Jeong, C.

    2015-05-01

    © 2015 Elsevier B.V. We discuss a systematic methodology for investigating the feasibility of mobilizing oil droplets trapped within the pore space of a target reservoir region by optimally directing wave energy to the region of interest. The motivation stems from field and laboratory observations, which have provided sufficient evidence suggesting that wave-based reservoir stimulation could lead to economically viable oil recovery.Using controlled active surface wave sources, we first describe the mathematical framework necessary for identifying optimal wave source signals that can maximize a desired motion metric (kinetic energy, particle acceleration, etc.) at the target region of interest. We use the apparatus of partial-differential-equation (PDE)-constrained optimization to formulate the associated inverse-source problem, and deploy state-of-the-art numerical wave simulation tools to resolve numerically the associated discrete inverse problem.Numerical experiments with a synthetic subsurface model featuring a shallow reservoir show that the optimizer converges to wave source signals capable of maximizing the motion within the reservoir. The spectra of the wave sources are dominated by the amplification frequencies of the formation. We also show that wave energy could be focused within the target reservoir area, while simultaneously minimizing the disturbance to neighboring formations - a concept that can also be exploited in fracking operations.Lastly, we compare the results of our numerical experiments conducted at the reservoir scale, with results obtained from semi-analytical studies at the granular level, to conclude that, in the case of shallow targets, the optimized wave sources are likely to mobilize trapped oil droplets, and thus enhance oil recovery.

  2. Maximizing the potential of internships in gerontology and geriatrics.

    Science.gov (United States)

    Karasik, Rona J

    2009-01-01

    Internships and similar applied opportunities have long been valued for providing students with opportunities for practical experience, career preparation, and personal growth. The need for applied experiences in gerontology and geriatrics is particularly salient. Creating and sustaining effective internship experiences, however, requires careful attention to a variety of concerns. Using examples and illustrations from an ongoing gerontology internship component (undergraduate and graduate) this article examines ways to anticipate and address the challenges that are common to a broad range of internship experiences, as well as those that are unique to applied learning in gerontology and geriatrics.

  3. Optimization of Second Fault Detection Thresholds to Maximize Mission POS

    Science.gov (United States)

    Anzalone, Evan

    2018-01-01

    both magnitude and time. As such, the Navigation team is taking advantage of the INS's capability to schedule and change fault detection thresholds in flight. These values are optimized along a nominal trajectory in order to maximize probability of mission success, and reducing the probability of false positives (defined as when the INS would report a second fault condition resulting in loss of mission, but the vehicle would still meet insertion requirements within system-level margins). This paper will describe an optimization approach using Genetic Algorithms to tune the threshold parameters to maximize vehicle resilience to second fault events as a function of potential fault magnitude and time of fault over an ascent mission profile. The analysis approach, and performance assessment of the results will be presented to demonstrate the applicability of this process to second fault detection to maximize mission probability of success.

  4. COOPERATIVE PRINCIPLE AND ITS MAXIMS OF COMMENTS IN TEXT YOUR SAY OF THE JAKARTA POST

    Directory of Open Access Journals (Sweden)

    Ahmad Fauzi Sulton

    2014-11-01

    Full Text Available This study aims to find what maxims and how the maxims are observed or infringed in text your sayof The Jakarta Post based on the cooperative principle and maxims. The research design of this study is descriptive qualitative. The resercher himself is the main instrument. He uses typological analysis (based on categories. In addition, investigator triangulation is usedtovalidate the analysis. The research results show that all maxims are observed and infringed. In this case, the most comments (42 comments from 53 gathered in „text your say’ of The Jakarta Post do not match the cooperative principle and they also infringe and observe one or some of the maxims.

  5. ROC-based utility function maximization for feature selection and classification with applications to high-dimensional protease data.

    Science.gov (United States)

    Liu, Zhenqiu; Tan, Ming

    2008-12-01

    In medical diagnosis, the diseased and nondiseased classes are usually unbalanced and one class may be more important than the other depending on the diagnosis purpose. Most standard classification methods, however, are designed to maximize the overall accuracy and cannot incorporate different costs to different classes explicitly. In this article, we propose a novel nonparametric method to directly maximize the weighted specificity and sensitivity of the receiver operating characteristic curve. Combining advances in machine learning, optimization theory, and statistics, the proposed method has excellent generalization property and assigns different error costs to different classes explicitly. We present experiments that compare the proposed algorithms with support vector machines and regularized logistic regression using data from a study on HIV-1 protease as well as six public available datasets. Our main conclusion is that the performance of proposed algorithm is significantly better in most cases than the other classifiers tested. Software package in MATLAB is available upon request.

  6. Technique of the transcervical-subxiphoid-videothoracoscopic maximal thymectomy

    Directory of Open Access Journals (Sweden)

    Zielinski Marcin

    2007-01-01

    Full Text Available Background: The aim of this study is to present the new technique of transcervical-subxiphoid-videothoracoscopic "maximal"thymectomy introduced by the authors of this study for myasthenia gravis. Materials and Methods: Two hundred and sixteen patients with Osserman scores ranging from I-III were operated on from 1/9/2000 to 31/12/2006 for this study. The operation was performed through four incisions: a transverse 5-8 cm incision in the neck, a 4-6 cm subxiphoid incision and two 1 cm incisions for videothoracoscopic (VTS ports. The cervical part of the procedure was performed with an open technique while the intrathoracic part was performed using a video-assisted thoracoscopic surgical (VATS technique. The whole thymus with the surrounding fatty tissue containing possible ectopic foci of the thymic tissue was removed. Such an operation can be performed by one surgical team (the one team approach or by two teams working simultaneously (two team approach. The early and late results as well as the incidence and localization of ectopic thymic foci have been presented in this report. Results: There were 216 patients in this study of which 178 were women and 38 were men. The ages of the patients ranged from 11 to 69 years (mean 29.7 years. The duration of myasthenia was 2-180 months (mean 28.3 months. Osserman scores were in the range of I-III. Almost 27% of the patients were taking steroids or immunosuppressive drugs preoperatively. The mean operative time was 201.5 min (120-330 min for a one-team approach and it was 146 (95-210 min for a two-team approach (P < 0.05. While there was no postoperative mortality, the postoperative morbidity was 12%. The incidence of ectopic thymic foci was 68.4%. The rates of complete remission after one, two, three, four and five years of follow-up were 26.3, 36.5, 42.9, 46.8 and 50.2%, respectively. Conclusion: Transcervical-subxiphoid-VTS maximal thymectomy is a complete and highly effective treatment modality for

  7. Maximally-localized position, Euclidean path-integral, and thermodynamics in GUP quantum mechanics

    Science.gov (United States)

    Bernardo, Reginald Christian S.; Esguerra, Jose Perico H.

    2018-04-01

    In dealing with quantum mechanics at very high energies, it is essential to adapt to a quasiposition representation using the maximally-localized states because of the generalized uncertainty principle. In this paper, we look at maximally-localized states as eigenstates of the operator ξ = X + iβP that we refer to as the maximally-localized position. We calculate the overlap between maximally-localized states and show that the identity operator can be expressed in terms of the maximally-localized states. Furthermore, we show that the maximally-localized position is diagonal in momentum-space and that the maximally-localized position and its adjoint satisfy commutation and anti-commutation relations reminiscent of the harmonic oscillator commutation and anti-commutation relations. As application, we use the maximally-localized position in developing the Euclidean path-integral and introduce the compact form of the propagator for maximal localization. The free particle momentum-space propagator and the propagator for maximal localization are analytically evaluated up to quadratic-order in β. Finally, we obtain a path-integral expression for the partition function of a thermodynamic system using the maximally-localized states. The partition function of a gas of noninteracting particles is evaluated. At temperatures exceeding the Planck energy, we obtain the gas' maximum internal energy N / 2 β and recover the zero heat capacity of an ideal gas.

  8. A New Look at the Impact of Maximizing on Unhappiness: Two Competing Mediating Effects

    Directory of Open Access Journals (Sweden)

    Jiaxi Peng

    2018-02-01

    Full Text Available The current study aims to explore how the decision-making style of maximizing affects subjective well-being (SWB, which mainly focuses on the confirmation of the mediator role of regret and suppressing role of achievement motivation. A total of 402 Chinese undergraduate students participated in this study, in which they responded to the maximization, regret, and achievement motivation scales and SWB measures. Results suggested that maximizing significantly predicted SWB. Moreover, regret and achievement motivation (hope for success dimension could completely mediate and suppress this effect. That is, two competing indirect pathways exist between maximizing and SWB. One pathway is through regret. Maximizing typically leads one to regret, which could negatively predict SWB. Alternatively, maximizing could lead to high levels of hope for success, which were positively correlated with SWB. Findings offered a complex method of thinking about the relationship between maximizing and SWB.

  9. Associations of maximal voluntary isometric hip extension torque with muscle size of hamstring and gluteus maximus and intra-abdominal pressure.

    Science.gov (United States)

    Tayashiki, Kota; Hirata, Kosuke; Ishida, Kiraku; Kanehisa, Hiroaki; Miyamoto, Naokazu

    2017-06-01

    Muscle size of the hamstring and gluteus maximus (GM) as well as intra-abdominal pressure (IAP) are considered as factors affecting the torque development during hip extension. This study examined the associations of torque development during maximal voluntary isometric hip extension with IAP and muscle size of the hamstring and GM. Anatomical cross-sectional area (ACSA) of the hamstring and thickness of GM were determined in 20 healthy young males using an ultrasonography apparatus (Experiment 1). Torque and IAP were simultaneously measured while subjects performed maximal voluntary isometric hip extension. The IAP was measured using a pressure transducer placed in the rectum and determined at the time at which the developed torque reached to the maximal. In Experiment 2, torque and IAP were measured during maximal voluntary isometric hip flexion in 18 healthy young males. The maximal hip extension torque was significantly correlated with the IAP (r = 0.504, P = 0.024), not with the ACSA of the hamstring (r = 0.307, P = 0.188) or the thickness of GM (r = 0.405, P = 0.076). The relationship was still significant even when the ACSA of the hamstring and the thickness of GM were adjusted statistically (r = 0.486, P = 0.041). The maximal hip flexion torque was not significantly correlated with the IAP (r = -0.118, P = 0.642). The current results suggest that IAP can contribute independently of the muscle size of the agonists to maximal voluntary hip extension torque.

  10. Comparison between static maximal force and handbrake pulling force.

    Science.gov (United States)

    Chateauroux, E; Wang, X

    2012-01-01

    The measurement of maximum pulling force is important not only for specifying force limit of industrial workers but also for designing controls requiring high force. This paper presents a comparison between maximal static handbrake pulling force (FST) and force exerted during normal handbrake pulling task (FDY). These forces were measured for different handle locations and subject characteristics. Participants were asked to pull a handbrake on an adjustable car mock-up as they would do when parking their own car, then to exert a force as high as possible on the pulled handbrake. Hand pulling forces were measured using a six-axes force sensor. 5 fixed handbrake positions were tested as well as a neutral handbrake position defined by the subject. FST and FDY were significantly correlated. Both were found to be dependent on handbrake position, age and gender. As expected, women and older subjects exerted lower forces. FST was significantly higher than FDY. The ratio FmR (FDY divided by FST) was also analyzed. Women showed higher FmR than men meaning that the task required a higher amount of muscle capability for women. FmR was also influenced by handbrake location. These data will be useful for handbrake design.

  11. Association of acceleration with spatiotemporal variables in maximal sprinting.

    Science.gov (United States)

    Nagahara, R; Naito, H; Morin, J-B; Zushi, K

    2014-08-01

    This study clarified the association between acceleration and the rates of changes in spatiotemporal variables on a step-to-step basis during the entire acceleration phase of maximal sprinting. 21 male sprinters performed a 60-m sprint, during which step-to-step acceleration and rates of changes in step length (RSL) and step frequency (RSF) were calculated. The coefficients of correlation between acceleration and other variables were tested at each step. There were positive correlations between acceleration and the RSF up to the second step. Acceleration was positively correlated with the RSL from the 5(th) to the 19(th) step. At the third and from the 16(th) to the 22(nd) step and from the 20(th) to the 21(st) step, there was no significant correlation, but weak relationships were found between acceleration and the RSF and RSL. The results suggest that the acceleration phase can be divided into 3 sections, and for sprinting to be effective, it is important to accelerate by increasing the step frequency to the third step, increasing the step length from the 5(th) to the 15(th) step, and increasing the step length or frequency (no systematic relative importance of step length or frequency) from the 16(th) step in the entire acceleration phase. © Georg Thieme Verlag KG Stuttgart · New York.

  12. MANAGING CONTENTION AVOIDANCE AND MAXIMIZING THROUGHPUT IN OBS NETWORK

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    AMIT KUMAR GARG

    2013-04-01

    Full Text Available Optical Burst Switching (OBS is a promising technology for future optical networks. Due to its less complicated implementation using current optical and electrical components, OBS is seen as the first step towards the future Optical Packet Switching (OPS. In OBS, a key problem is to schedule bursts on wavelength channels whose bandwidth may become fragmented with the so-called void (or idle intervals with both fast and bandwidth efficient algorithms so as to reduce burst loss. In this paper, a new scheme has been proposed to improve the throughput and to avoid the contention in the OBS network. The proposed scheme offers the same node complexity as that in general OBS networks with optical buffers. Also, it avoids burst blockings in transit nodes, turning it into an efficient and simple burst contention avoidance mechanism. Simulation results show that the proposed scheme has improvement of 15% in terms of burst loss probability as compared to OBS existing schemes and also maximizes the throughput of the network without deteriorating excessively other parameters such as end to end delay or ingress queues.

  13. Begin, After, and Later: a Maximal Decidable Interval Temporal Logic

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    Davide Bresolin

    2010-06-01

    Full Text Available Interval temporal logics (ITLs are logics for reasoning about temporal statements expressed over intervals, i.e., periods of time. The most famous ITL studied so far is Halpern and Shoham's HS, which is the logic of the thirteen Allen's interval relations. Unfortunately, HS and most of its fragments have an undecidable satisfiability problem. This discouraged the research in this area until recently, when a number non-trivial decidable ITLs have been discovered. This paper is a contribution towards the complete classification of all different fragments of HS. We consider different combinations of the interval relations Begins, After, Later and their inverses Abar, Bbar, and Lbar. We know from previous works that the combination ABBbarAbar is decidable only when finite domains are considered (and undecidable elsewhere, and that ABBbar is decidable over the natural numbers. We extend these results by showing that decidability of ABBar can be further extended to capture the language ABBbarLbar, which lays in between ABBar and ABBbarAbar, and that turns out to be maximal w.r.t decidability over strongly discrete linear orders (e.g. finite orders, the naturals, the integers. We also prove that the proposed decision procedure is optimal with respect to the complexity class.

  14. Maximal force and tremor changes across the menstrual cycle.

    Science.gov (United States)

    Tenan, Matthew S; Hackney, Anthony C; Griffin, Lisa

    2016-01-01

    Sex hormones have profound effects on the nervous system in vitro and in vivo. The present study examines the effect of the menstrual cycle on maximal isometric force (MVC) and tremor during an endurance task. Nine eumenorrheic females participated in five study visits across their menstrual cycle. In each menstrual phase, an MVC and an endurance task to failure were performed. Tremor across the endurance task was quantified as the coefficient of variation in force and was assessed in absolute time and relative percent time to task failure. MVC decreases 23% from ovulation to the mid luteal phase of the menstrual cycle. In absolute time, the mid luteal phase has the highest initial tremor, though the early follicular phase has substantially higher tremor than other phases after 150 s of task performance. In relative time, the mid luteal phase has the highest level of tremor throughout the endurance task. Both MVC and tremor during an endurance task are modified by the menstrual cycle. Performance of tasks and sports which require high force and steadiness to exhaustion may be decreased in the mid luteal phase compared to other menstrual phases.

  15. Terminal altitude maximization for Mars entry considering uncertainties

    Science.gov (United States)

    Cui, Pingyuan; Zhao, Zeduan; Yu, Zhengshi; Dai, Juan

    2018-04-01

    Uncertainties present in the Mars atmospheric entry process may cause state deviations from the nominal designed values, which will lead to unexpected performance degradation if the trajectory is designed merely based on the deterministic dynamic model. In this paper, a linear covariance based entry trajectory optimization method is proposed considering the uncertainties presenting in the initial states and parameters. By extending the elements of the state covariance matrix as augmented states, the statistical behavior of the trajectory is captured to reformulate the performance metrics and path constraints. The optimization problem is solved by the GPOPS-II toolbox in MATLAB environment. Monte Carlo simulations are also conducted to demonstrate the capability of the proposed method. Primary trading performances between the nominal deployment altitude and its dispersion can be observed by modulating the weights on the dispersion penalty, and a compromised result referring to maximizing the 3σ lower bound of the terminal altitude is achieved. The resulting path constraints also show better satisfaction in a disturbed environment compared with the nominal situation.

  16. Maximizing recovery of water-soluble proteins through acetone precipitation.

    Science.gov (United States)

    Crowell, Andrew M J; Wall, Mark J; Doucette, Alan A

    2013-09-24

    Solvent precipitation is commonly used to purify protein samples, as seen with the removal of sodium dodecyl sulfate through acetone precipitation. However, in its current practice, protein loss is believed to be an inevitable consequence of acetone precipitation. We herein provide an in depth characterization of protein recovery through acetone precipitation. In 80% acetone, the precipitation efficiency for six of 10 protein standards was poor (ca. ≤15%). Poor recovery was also observed for proteome extracts, including bacterial and mammalian cells. As shown in this work, increasing the ionic strength of the solution dramatically improves the precipitation efficiency of individual proteins, and proteome mixtures (ca. 80-100% yield). This is obtained by including 1-30 mM NaCl, together with acetone (50-80%) which maximizes protein precipitation efficiency. The amount of salt required to restore the recovery correlates with the amount of protein in the sample, as well as the intrinsic protein charge, and the dielectric strength of the solution. This synergistic approach to protein precipitation in acetone with salt is consistent with a model of ion pairing in organic solvent, and establishes an improved method to recover proteins and proteome mixtures in high yield. Copyright © 2013 Elsevier B.V. All rights reserved.

  17. Computerized detection of masses on mammograms by entropy maximization thresholding

    International Nuclear Information System (INIS)

    Kom, Guillaume; Tiedeu, Alain; Feudjio, Cyrille; Ngundam, J.

    2010-03-01

    In many cases, masses in X-ray mammograms are subtle and their detection can benefit from an automated system serving as a diagnostic aid. It is to this end that the authors propose in this paper, a new computer aided mass detection for breast cancer diagnosis. The first step focuses on wavelet filters enhancement which removes bright background due to dense breast tissues and some film artifacts while preserving features and patterns related to the masses. In the second step, enhanced image is computed by Entropy Maximization Thresholding (EMT) to obtain segmented masses. The efficiency of 98,181% is achieved by analyzing a database of 84 mammograms previously marked by radiologists and digitized at a pixel size of 343μmm x 343μ mm. The segmentation results, in terms of size of detected masses, give a relative error on mass area that is less than 8%. The performance of the proposed method has also been evaluated by means of the receiver operating-characteristics (ROC) analysis. This yielded respectively, an area (Az) of 0.9224 and 0.9295 under the ROC curve whether enhancement step is applied or not. Furthermore, we observe that the EMT yields excellent segmentation results compared to those found in literature. (author)

  18. Crouched Posture Maximizes Ground Reaction Forces Generated by Muscles

    Science.gov (United States)

    Hoang, Hoa X.; Reinbolt, Jeffrey A.

    2012-01-01

    Crouch gait decreases walking efficiency due to the increased knee and hip flexion during the stance phase of gait. Crouch gait is generally considered to be disadvantageous for children with cerebral palsy; however, a crouched posture may allow biomechanical advantages that lead some children to adopt a crouch gait. To investigate one possible advantage of crouch gait, a musculoskeletal model created in OpenSim was placed in 15 different postures from upright to severe crouch during initial, middle, and final stance of the gait cycle for a total of 45 different postures. A series of optimizations was performed for each posture to maximize transverse plane ground reaction forces in the 8 compass directions by modifying muscle forces acting on the model. We compared the force profile areas across all postures. Larger force profile areas were allowed by postures from mild crouch (for initial stance) to crouch (for final stance). The overall ability to generate larger ground reaction force profiles represents a mechanical advantage of a crouched posture. This increase in muscle capacity while in a crouched posture may allow a patient to generate new movements to compensate for impairments associated with cerebral palsy, such as motor control deficits. PMID:22542242

  19. Anesthetic constituents of Zanthoxylum bungeanum Maxim.: A pharmacokinetic study.

    Science.gov (United States)

    Rong, Rong; Cui, Mei-Yu; Zhang, Qi-Li; Zhang, Mei-Yan; Yu, Yu-Ming; Zhou, Xian-Ying; Yu, Zhi-Guo; Zhao, Yun-Li

    2016-07-01

    A sensitive and selective ultra high performance liquid chromatography with tandem mass spectrometry method was established and validated for the simultaneous determination of hydroxy-α-sanshool, hydroxy-β-sanshool, and hydroxy-γ-sanshool in rat plasma after the subcutaneous and intravenous administration of an extract of the pericarp of Zanthoxylum bungeanum Maxim. Piperine was used as the internal standard. The analytes were extracted from rat plasma by liquid-liquid extraction with ethyl acetate and separated on a Thermo Hypersil GOLD C18 column (2.1 mm × 50 mm, 1.9 μm) with a gradient elution system at a flow rate of 0.4 mL/min. The mobile phase consisted of acetonitrile/0.05% formic acid in water and the total analysis time was 4 min. Positive electrospray ionization was performed using multiple reaction monitoring mode for the analytes. The calibration curves of the three analytes were linear over the tested concentration range. The intra- and interday precision was no more than 13.6%. Extraction recovery, matrix effect, and stability were satisfactory in rat plasma. The developed and validated method was suitable for the quantification of hydroxy-α-sanshool, hydroxy-β-sanshool, and hydroxy-γ-sanshool and successfully applied to a pharmacokinetic study of these analytes after subcutaneous and intravenous administration to rats. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Predicting maximal aerobic speed through set distance time-trials.

    Science.gov (United States)

    Bellenger, Clint R; Fuller, Joel T; Nelson, Maximillian J; Hartland, Micheal; Buckley, Jonathan D; Debenedictis, Thomas A

    2015-12-01

    Knowledge of aerobic performance capacity allows for the optimisation of training programs in aerobically dominant sports. Maximal aerobic speed (MAS) is a measure of aerobic performance; however, the time and personnel demands of establishing MAS are considerable. This study aimed to determine whether time-trials (TT), which are shorter and less onerous than traditional MAS protocols, may be used to predict MAS. 28 Australian Rules football players completed a test of MAS, followed by TTs of six different distances in random order, each separated by at least 48 h. Half of the participants completed TT distances of 1200, 1600 and 2000 m, and the others completed distances of 1400, 1800 and 2200 m. Average speed for the 1200 and 1400 m TTs were greater than MAS (P speed for 1600, 1800, 2000 and 2200 m TTs were not different from MAS (P > 0.08). Average speed for all TT distances correlated with MAS (r = 0.69-0.84; P speed and MAS with increasing TT distance (r = -0.79; P speed over the 2000 m distance exhibited the best agreement with MAS. MAS may be predicted from the average speed during a TT for any distance between 1200 and 2200 m, with 2000 m being optimal. Performance of a TT may provide a simple alternative to traditional MAS testing.

  1. On gauged maximal d  =  8 supergravities

    Science.gov (United States)

    Lasso Andino, Óscar; Ortín, Tomás

    2018-04-01

    We study the gauging of maximal d  =  8 supergravity using the embedding tensor formalism. We focus on SO(3) gaugings, study all the possible choices of gauge fields and construct explicitly the bosonic actions (including the complicated Chern–Simons terms) for all these choices, which are parametrized by a parameter associated to the 8-dimensional SL(2, {R}) duality group that relates all the possible choices which are, ultimately, equivalent from the purely 8-dimensional point of view. Our result proves that the theory constructed by Salam and Sezgin by Scherk–Schwarz compactification of d  =  11 supergravity and the theory constructed in Alonso-Alberca (2001 Nucl. Phys. B 602 329) by dimensional reduction of the so called ‘massive 11-dimensional supergravity’ proposed by Meessen and Ortín in (1999 Nucl. Phys. B 541 195) are indeed related by an SL(2, {R}) duality even though they have two completely different 11-dimensional origins.

  2. Renewable Substitutability Index: Maximizing Renewable Resource Use in Buildings

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    Ravi S. Srinivasan

    2015-05-01

    Full Text Available In order to achieve a material and energy balance in buildings that is sustainable in the long run, there is an urgent need to assess the renewable and non-renewable resources used in the manufacturing process and to progressively replace non-renewable resources with renewables. Such progressive disinvestment in the non-renewable resources that may be substituted with renewable resources is referred to as “Renewable Substitutability” and if implemented, this process will lead to a paradigm shift in the way building materials are manufactured. This paper discusses the development of a Renewable Substitutability Index (RSI that is designed to maximize the use of renewable resources in a building and quantifies the substitution process using solar emergy (i.e., the solar equivalent joules required for any item. The RSI of a building or a building component, i.e., floor or wall systems, etc., is the ratio of the renewable resources used during construction, including replacement and maintenance, to the building’s maximum renewable emergy potential. RSI values range between 0 and 1.0. A higher RSI achieves a low-energy building strategy promoting a higher order of sustainability by optimizing the use of renewables over a building’s lifetime from formation-extraction-manufacturing to maintenance, operation, demolition, and recycle.

  3. The maximal operator in weighted variable spaces Lp(⋅

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    Vakhtang Kokilashvili

    2007-01-01

    Full Text Available We study the boundedness of the maximal operator in the weighted spaces Lp(⋅(ρ over a bounded open set Ω in the Euclidean space ℝn or a Carleson curve Γ in a complex plane. The weight function may belong to a certain version of a general Muckenhoupt-type condition, which is narrower than the expected Muckenhoupt condition for variable exponent, but coincides with the usual Muckenhoupt class Ap in the case of constant p. In the case of Carleson curves there is also considered another class of weights of radial type of the form ρ(t=∏k=1mwk(|t-tk|, tk∈Γ, where wk has the property that r1p(tkwk(r∈Φ10, where Φ10 is a certain Zygmund-Bari-Stechkin-type class. It is assumed that the exponent p(t satisfies the Dini–Lipschitz condition. For such radial type weights the final statement on the boundedness is given in terms of the index numbers of the functions wk (similar in a sense to the Boyd indices for the Young functions defining Orlich spaces.

  4. Moderate intra-group bias maximizes cooperation on interdependent populations.

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    Changbing Tang

    Full Text Available Evolutionary game theory on spatial structures has received increasing attention during the past decades. However, the majority of these achievements focuses on single and static population structures, which is not fully consistent with the fact that real structures are composed of many interactive groups. These groups are interdependent on each other and present dynamical features, in which individuals mimic the strategy of neighbors and switch their partnerships continually. It is however unclear how the dynamical and interdependent interactions among groups affect the evolution of collective behaviors. In this work, we employ the prisoner's dilemma game to investigate how the dynamics of structure influences cooperation on interdependent populations, where populations are represented by group structures. It is found that the more robust the links between cooperators (or the more fragile the links between cooperators and defectors, the more prevalent of cooperation. Furthermore, theoretical analysis shows that the intra-group bias can favor cooperation, which is only possible when individuals are likely to attach neighbors within the same group. Yet, interestingly, cooperation can be even inhibited for large intra-group bias, allowing the moderate intra-group bias maximizes the cooperation level.

  5. Gaze-enabled Egocentric Video Summarization via Constrained Submodular Maximization.

    Science.gov (United States)

    Xut, Jia; Mukherjee, Lopamudra; Li, Yin; Warner, Jamieson; Rehg, James M; Singht, Vikas

    2015-06-01

    With the proliferation of wearable cameras, the number of videos of users documenting their personal lives using such devices is rapidly increasing. Since such videos may span hours, there is an important need for mechanisms that represent the information content in a compact form (i.e., shorter videos which are more easily browsable/sharable). Motivated by these applications, this paper focuses on the problem of egocentric video summarization. Such videos are usually continuous with significant camera shake and other quality issues. Because of these reasons, there is growing consensus that direct application of standard video summarization tools to such data yields unsatisfactory performance. In this paper, we demonstrate that using gaze tracking information (such as fixation and saccade) significantly helps the summarization task. It allows meaningful comparison of different image frames and enables deriving personalized summaries (gaze provides a sense of the camera wearer's intent). We formulate a summarization model which captures common-sense properties of a good summary, and show that it can be solved as a submodular function maximization with partition matroid constraints, opening the door to a rich body of work from combinatorial optimization. We evaluate our approach on a new gaze-enabled egocentric video dataset (over 15 hours), which will be a valuable standalone resource.

  6. Managing the innovation supply chain to maximize personalized medicine.

    Science.gov (United States)

    Waldman, S A; Terzic, A

    2014-02-01

    Personalized medicine epitomizes an evolving model of care tailored to the individual patient. This emerging paradigm harnesses radical technological advances to define each patient's molecular characteristics and decipher his or her unique pathophysiological processes. Translated into individualized algorithms, personalized medicine aims to predict, prevent, and cure disease without producing therapeutic adverse events. Although the transformative power of personalized medicine is generally recognized by physicians, patients, and payers, the complexity of translating discoveries into new modalities that transform health care is less appreciated. We often consider the flow of innovation and technology along a continuum of discovery, development, regulation, and application bridging the bench with the bedside. However, this process also can be viewed through a complementary prism, as a necessary supply chain of services and providers, each making essential contributions to the development of the final product to maximize value to consumers. Considering personalized medicine in this context of supply chain management highlights essential points of vulnerability and/or scalability that can ultimately constrain translation of the biological revolution or potentiate it into individualized diagnostics and therapeutics for optimized value creation and delivery.

  7. Maximal accumulated oxygen deficit as a predictor of anaerobic capacity

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    Emerson Franchini

    2006-03-01

    Full Text Available The maximal accumulated oxygen deficit (MAOD has been considered as one of the most adequate measures of anaerobic capacity. It is based on the numerical difference between the total energy demand of a severe exercise bout and the energy portion associated to the total oxygen consumption. However, the debate around the measurement procedures and the validity of the assumptions persist. The present review was done to describe and discuss these measurement procedures, as well as the validity evidences of MAOD. Finally, critical questions about the methodology of measurement of this physiological variable are discussed. RESUMO O máximo déficit acumulado de oxigênio (MAOD vem sendo apontado como uma das medidas mais adequadas de capacidade anaeróbia. Ele se baseia na diferença numérica entre a demanda energética total de um exercício severo e a porção de energia associada ao consumo total de oxigênio. Ainda há debate na literatura sobre seus procedimentos de medida e validade dos pressupostos. A presente revisão foi feita para descrever e discutir esses procedimentos de medida, bem como as evidências de validade do MAOD. Por fim, são discutidas questões críticas da metodologia empregada na medida dessa variável fisiológica.

  8. Optimal optical communication terminal structure for maximizing the link budget

    Science.gov (United States)

    Huang, Jian; Jiang, Dagang; Deng, Ke; Zhang, Peng

    2015-02-01

    Ordinary inter-satellite optical includes at least three optical paths for acquisition, tracking and communication, the three optical paths work simultaneously and share the received power. An optimal structure of inter-satellite optical communication terminal with single working optical path at each of working stages of acquisition and communication is introduced. A space optical switch based on frustrated total internal reflection effect is applied to switch the received laser power between the acquisition sensor and the communication sensor between the stages of acquisition and communication, this is named as power fusion which means power is transferred for shutting down unused optical path. For the stages of tracking and communication, a multiple cells sensor is used to accomplish the operation of tracking while communication, this is named as function fusion which means accomplishing multiple functions by one device to reduce the redundant optical paths. For optical communication terminal with single working path structure, the total received laser power would be detected by one sensor for each different stages of acquisition, tracking and communication, the link budget would be maximized, and this design would help to enlarge the system tolerance and reduce the acquisition time.

  9. Blood detection in wireless capsule endoscopy using expectation maximization clustering

    Science.gov (United States)

    Hwang, Sae; Oh, JungHwan; Cox, Jay; Tang, Shou Jiang; Tibbals, Harry F.

    2006-03-01

    Wireless Capsule Endoscopy (WCE) is a relatively new technology (FDA approved in 2002) allowing doctors to view most of the small intestine. Other endoscopies such as colonoscopy, upper gastrointestinal endoscopy, push enteroscopy, and intraoperative enteroscopy could be used to visualize up to the stomach, duodenum, colon, and terminal ileum, but there existed no method to view most of the small intestine without surgery. With the miniaturization of wireless and camera technologies came the ability to view the entire gestational track with little effort. A tiny disposable video capsule is swallowed, transmitting two images per second to a small data receiver worn by the patient on a belt. During an approximately 8-hour course, over 55,000 images are recorded to a worn device and then downloaded to a computer for later examination. Typically, a medical clinician spends more than two hours to analyze a WCE video. Research has been attempted to automatically find abnormal regions (especially bleeding) to reduce the time needed to analyze the videos. The manufacturers also provide the software tool to detect the bleeding called Suspected Blood Indicator (SBI), but its accuracy is not high enough to replace human examination. It was reported that the sensitivity and the specificity of SBI were about 72% and 85%, respectively. To address this problem, we propose a technique to detect the bleeding regions automatically utilizing the Expectation Maximization (EM) clustering algorithm. Our experimental results indicate that the proposed bleeding detection method achieves 92% and 98% of sensitivity and specificity, respectively.

  10. Network architecture underlying maximal separation of neuronal representations

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    Ron A Jortner

    2013-01-01

    Full Text Available One of the most basic and general tasks faced by all nervous systems is extracting relevant information from the organism’s surrounding world. While physical signals available to sensory systems are often continuous, variable, overlapping and noisy, high-level neuronal representations used for decision-making tend to be discrete, specific, invariant, and highly separable. This study addresses the question of how neuronal specificity is generated. Inspired by experimental findings on network architecture in the olfactory system of the locust, I construct a highly simplified theoretical framework which allows for analytic solution of its key properties. For generalized feed-forward systems, I show that an intermediate range of connectivity values between source- and target-populations leads to a combinatorial explosion of wiring possibilities, resulting in input spaces which are, by their very nature, exquisitely sparsely populated. In particular, connection probability ½, as found in the locust antennal-lobe–mushroom-body circuit, serves to maximize separation of neuronal representations across the target Kenyon-cells, and explains their specific and reliable responses. This analysis yields a function expressing response specificity in terms of lower network-parameters; together with appropriate gain control this leads to a simple neuronal algorithm for generating arbitrarily sparse and selective codes and linking network architecture and neural coding. I suggest a way to easily construct ecologically meaningful representations from this code.

  11. Maximizing Utilization of Energy from Crop By-products

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    Budi Haryanto

    2014-03-01

    Full Text Available The availability of crop by-products is huge during harvesting times as related to the vast agricultural land area; however, their utilization is still limited due to lack of knowledge and handling problem. Seasonal effect is obvious especially during wet season when high rainfall hinders proper management of crop by-products. Crop by-products are energy rich feedstuffs in the form of chemical substance such as cellulose and hemicellulose. The utilization of cellulose and hemicellulose as sources of energy can be maximized by the application of technologies to increase the digestibility. Cellulose is polymer of glucose while hemicellulose is polymer of xylose which both can be converted to volatile fatty acids by rumen microbial enzyme activities and subsequently used by the host animal as source of energy. In addition, cellulose and hemicellulose can also be used as substrates for bioethanol production leaving behind residual matter with higher concentration of protein which is also appropriate for ruminant feeds. The fat content of crop by-products such as those in rice bran and corn germ can be extracted for oil production that can be used for human consumption with concomitant production of high nutritive value of residues for ruminant feeds. The oil extraction technologies are available; however the high cost of ethanol and oil production should obtain high attention to make the technologies more applicable at farmers’ level.

  12. A maximally selected test of symmetry about zero.

    Science.gov (United States)

    Laska, Eugene; Meisner, Morris; Wanderling, Joseph

    2012-11-20

    The problem of testing symmetry about zero has a long and rich history in the statistical literature. We introduce a new test that sequentially discards observations whose absolute value is below increasing thresholds defined by the data. McNemar's statistic is obtained at each threshold and the largest is used as the test statistic. We obtain the exact distribution of this maximally selected McNemar and provide tables of critical values and a program for computing p-values. Power is compared with the t-test, the Wilcoxon Signed Rank Test and the Sign Test. The new test, MM, is slightly less powerful than the t-test and Wilcoxon Signed Rank Test for symmetric normal distributions with nonzero medians and substantially more powerful than all three tests for asymmetric mixtures of normal random variables with or without zero medians. The motivation for this test derives from the need to appraise the safety profile of new medications. If pre and post safety measures are obtained, then under the null hypothesis, the variables are exchangeable and the distribution of their difference is symmetric about a zero median. Large pre-post differences are the major concern of a safety assessment. The discarded small observations are not particularly relevant to safety and can reduce power to detect important asymmetry. The new test was utilized on data from an on-road driving study performed to determine if a hypnotic, a drug used to promote sleep, has next day residual effects. Copyright © 2012 John Wiley & Sons, Ltd.

  13. Expectation-Maximization Tensor Factorization for Practical Location Privacy Attacks

    Directory of Open Access Journals (Sweden)

    Murakami Takao

    2017-10-01

    Full Text Available Location privacy attacks based on a Markov chain model have been widely studied to de-anonymize or de-obfuscate mobility traces. An adversary can perform various kinds of location privacy attacks using a personalized transition matrix, which is trained for each target user. However, the amount of training data available to the adversary can be very small, since many users do not disclose much location information in their daily lives. In addition, many locations can be missing from the training traces, since many users do not disclose their locations continuously but rather sporadically. In this paper, we show that the Markov chain model can be a threat even in this realistic situation. Specifically, we focus on a training phase (i.e. mobility profile building phase and propose Expectation-Maximization Tensor Factorization (EMTF, which alternates between computing a distribution of missing locations (E-step and computing personalized transition matrices via tensor factorization (M-step. Since the time complexity of EMTF is exponential in the number of missing locations, we propose two approximate learning methods, one of which uses the Viterbi algorithm while the other uses the Forward Filtering Backward Sampling (FFBS algorithm. We apply our learning methods to a de-anonymization attack and a localization attack, and evaluate them using three real datasets. The results show that our learning methods significantly outperform a random guess, even when there is only one training trace composed of 10 locations per user, and each location is missing with probability 80% (i.e. even when users hardly disclose two temporally-continuous locations.

  14. Maximal zero textures in Linear and Inverse seesaw

    Directory of Open Access Journals (Sweden)

    Roopam Sinha

    2016-08-01

    Full Text Available We investigate Linear and Inverse seesaw mechanisms with maximal zero textures of the constituent matrices subjected to the assumption of non-zero eigenvalues for the neutrino mass matrix mν and charged lepton mass matrix me. If we restrict to the minimally parametrized non-singular ‘me’ (i.e., with maximum number of zeros it gives rise to only 6 possible textures of me. Non-zero determinant of mν dictates six possible textures of the constituent matrices. We ask in this minimalistic approach, what phenomenologically allowed maximum zero textures are possible. It turns out that Inverse seesaw leads to 7 allowed two-zero textures while the Linear seesaw leads to only one. In Inverse seesaw, we show that 2 is the maximum number of independent zeros that can be inserted into μS to obtain all 7 viable two-zero textures of mν. On the other hand, in Linear seesaw mechanism, the minimal scheme allows maximum 5 zeros to be accommodated in ‘m’ so as to obtain viable effective neutrino mass matrices (mν. Interestingly, we find that our minimalistic approach in Inverse seesaw leads to a realization of all the phenomenologically allowed two-zero textures whereas in Linear seesaw only one such texture is viable. Next, our numerical analysis shows that none of the two-zero textures give rise to enough CP violation or significant δCP. Therefore, if δCP=π/2 is established, our minimalistic scheme may still be viable provided we allow larger number of parameters in ‘me’.

  15. Kettlebell swing training improves maximal and explosive strength.

    Science.gov (United States)

    Lake, Jason P; Lauder, Mike A

    2012-08-01

    The aim of this study was to establish the effect that kettlebell swing (KB) training had on measures of maximum (half squat-HS-1 repetition maximum [1RM]) and explosive (vertical jump height-VJH) strength. To put these effects into context, they were compared with the effects of jump squat power training (JS-known to improve 1RM and VJH). Twenty-one healthy men (age = 18-27 years, body mass = 72.58 ± 12.87 kg) who could perform a proficient HS were tested for their HS 1RM and VJH pre- and post-training. Subjects were randomly assigned to either a KB or JS training group after HS 1RM testing and trained twice a week. The KB group performed 12-minute bouts of KB exercise (12 rounds of 30-second exercise, 30-second rest with 12 kg if 70 kg). The JS group performed at least 4 sets of 3 JS with the load that maximized peak power-Training volume was altered to accommodate different training loads and ranged from 4 sets of 3 with the heaviest load (60% 1RM) to 8 sets of 6 with the lightest load (0% 1RM). Maximum strength improved by 9.8% (HS 1RM: 165-181% body mass, p < 0.001) after the training intervention, and post hoc analysis revealed that there was no significant difference between the effect of KB and JS training (p = 0.56). Explosive strength improved by 19.8% (VJH: 20.6-24.3 cm) after the training intervention, and post hoc analysis revealed that the type of training did not significantly affect this either (p = 0.38). The results of this study clearly demonstrate that 6 weeks of biweekly KB training provides a stimulus that is sufficient to increase both maximum and explosive strength offering a useful alternative to strength and conditioning professionals seeking variety for their athletes.

  16. Reconstruction of phylogenetic trees of prokaryotes using maximal common intervals.

    Science.gov (United States)

    Heydari, Mahdi; Marashi, Sayed-Amir; Tusserkani, Ruzbeh; Sadeghi, Mehdi

    2014-10-01

    One of the fundamental problems in bioinformatics is phylogenetic tree reconstruction, which can be used for classifying living organisms into different taxonomic clades. The classical approach to this problem is based on a marker such as 16S ribosomal RNA. Since evolutionary events like genomic rearrangements are not included in reconstructions of phylogenetic trees based on single genes, much effort has been made to find other characteristics for phylogenetic reconstruction in recent years. With the increasing availability of completely sequenced genomes, gene order can be considered as a new solution for this problem. In the present work, we applied maximal common intervals (MCIs) in two or more genomes to infer their distance and to reconstruct their evolutionary relationship. Additionally, measures based on uncommon segments (UCS's), i.e., those genomic segments which are not detected as part of any of the MCIs, are also used for phylogenetic tree reconstruction. We applied these two types of measures for reconstructing the phylogenetic tree of 63 prokaryotes with known COG (clusters of orthologous groups) families. Similarity between the MCI-based (resp. UCS-based) reconstructed phylogenetic trees and the phylogenetic tree obtained from NCBI taxonomy browser is as high as 93.1% (resp. 94.9%). We show that in the case of this diverse dataset of prokaryotes, tree reconstruction based on MCI and UCS outperforms most of the currently available methods based on gene orders, including breakpoint distance and DCJ. We additionally tested our new measures on a dataset of 13 closely-related bacteria from the genus Prochlorococcus. In this case, distances like rearrangement distance, breakpoint distance and DCJ proved to be useful, while our new measures are still appropriate for phylogenetic reconstruction. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  17. Maximizing and stabilizing luminescence from halide perovskites with potassium passivation

    Science.gov (United States)

    Abdi-Jalebi, Mojtaba; Andaji-Garmaroudi, Zahra; Cacovich, Stefania; Stavrakas, Camille; Philippe, Bertrand; Richter, Johannes M.; Alsari, Mejd; Booker, Edward P.; Hutter, Eline M.; Pearson, Andrew J.; Lilliu, Samuele; Savenije, Tom J.; Rensmo, Håkan; Divitini, Giorgio; Ducati, Caterina; Friend, Richard H.; Stranks, Samuel D.

    2018-03-01

    Metal halide perovskites are of great interest for various high-performance optoelectronic applications. The ability to tune the perovskite bandgap continuously by modifying the chemical composition opens up applications for perovskites as coloured emitters, in building-integrated photovoltaics, and as components of tandem photovoltaics to increase the power conversion efficiency. Nevertheless, performance is limited by non-radiative losses, with luminescence yields in state-of-the-art perovskite solar cells still far from 100 per cent under standard solar illumination conditions. Furthermore, in mixed halide perovskite systems designed for continuous bandgap tunability (bandgaps of approximately 1.7 to 1.9 electronvolts), photoinduced ion segregation leads to bandgap instabilities. Here we demonstrate substantial mitigation of both non-radiative losses and photoinduced ion migration in perovskite films and interfaces by decorating the surfaces and grain boundaries with passivating potassium halide layers. We demonstrate external photoluminescence quantum yields of 66 per cent, which translate to internal yields that exceed 95 per cent. The high luminescence yields are achieved while maintaining high mobilities of more than 40 square centimetres per volt per second, providing the elusive combination of both high luminescence and excellent charge transport. When interfaced with electrodes in a solar cell device stack, the external luminescence yield—a quantity that must be maximized to obtain high efficiency—remains as high as 15 per cent, indicating very clean interfaces. We also demonstrate the inhibition of transient photoinduced ion-migration processes across a wide range of mixed halide perovskite bandgaps in materials that exhibit bandgap instabilities when unpassivated. We validate these results in fully operating solar cells. Our work represents an important advance in the construction of tunable metal halide perovskite films and interfaces that can

  18. Maximizing Symmetry in Upper Blepharoplasty: The Role of Microptosis Surgery.

    Science.gov (United States)

    Lew, Helen; Goldberg, Robert Alan

    2016-02-01

    Traditional descriptions of blepharoplasty and ptosis surgery focus on the incision and eyelid crease. However, it may be more useful to consider the tarsal platform show as the important construct in analyzing and planning aesthetic eyelid surgery. In order to measure and characterize the key contours of the eyelid, the authors find it helpful to consider the brow fat span, tarsal platform show, and margin reflex distance. Subtle eyelid ptosis can result in asymmetry by lengthening the tarsal platform show, and it is exacerbated by the tendency for the eyebrow to compensate. When ptosis is asymmetric, the plan should usually include asymmetric ptosis surgery. There are two general patterns that can be recognized and used for planning to address preoperative tarsal platform show asymmetry. If the tarsal platform show is longer on the side with worse blepharoptosis, then asymmetric or unilateral ptosis surgery will improve symmetry. In the cases of symmetric show despite asymmetric blepharoptosis, there may be bony and soft-tissue asymmetry, which leads to crowding of the orbit on the more ptotic side. Surgical planning should include consideration to increase the tarsal platform show on the more crowded side. It is not necessary to cut the eyelid skin in order to alter the tarsal show and brow fat span; ptosis surgery alone, by altering the eyelid position and eyebrow compensation, can reset the tarsal platform show/brow fat span relationship. It is important to recognize preoperative asymmetry, to predict the resetting of compensatory mechanisms, and to design asymmetric surgery, in order to maximize postoperative symmetry.

  19. Maximizing children's physical activity using the LET US Play principles.

    Science.gov (United States)

    Brazendale, Keith; Chandler, Jessica L; Beets, Michael W; Weaver, Robert G; Beighle, Aaron; Huberty, Jennifer L; Moore, Justin B

    2015-07-01

    Staff in settings that care for children struggle to implement standards designed to promote moderate-to-vigorous physical activity (MVPA), suggesting a need for effective strategies to maximize the amount of time children spend in MVPA during scheduled PA opportunities. The purpose of this study was to compare the MVPA children accumulate during commonly played games delivered in their traditional format versus games modified according to the LET US Play principles. Children (K-5th) participated in 1-hour PA sessions delivered on non-consecutive days (summer 2014). Using a randomized, counterbalanced design, one of the six games was played for 20min using either traditional rules or LET US Play followed by the other strategy with a 10min break in between. Physical activity was measured via accelerometry. Repeated-measures, mixed-effects regression models were used to estimate differences in percent of time spent sedentary and in MVPA. A total of 267 children (age 7.5years, 43% female, 29% African American) participated in 50, 1-hour activity sessions. Games incorporating LET US Play elicited more MVPA from both boys and girls compared to the same games with traditional rules. For boys and girls, the largest MVPA difference occurred during tag games (+20.3%). The largest reduction in the percent of time sedentary occurred during tag games (boys -27.7%, girls -32.4%). Overall, the percentage of children meeting 50% time in MVPA increased in four games (+18.7% to +53.1%). LET US Play led to greater accumulation of MVPA for boys and girls, and can increase the percent of children attaining the 50% of time in MVPA standard. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. Maximizing the functional lifetime of Protein A resins.

    Science.gov (United States)

    Zhang, Jennifer; Siva, Sethu; Caple, Ryan; Ghose, Sanchayita; Gronke, Rob

    2017-05-01

    Protein A chromatography is currently the industry gold-standard for monoclonal antibody and Fc-fusion protein purification. The high cost of Protein A, however, makes resin lifetime and resin reuse an important factor for process economics. Typical resin lifetime studies performed in the industry usually examine the effect of resin re-use on binding capacity, yield, and product quality without answering the fundamental question of what is causing the decrease in performance. A two part mechanistic study was conducted in an attempt to decouple the effect of the two possible factors (resin hydrolysis and/or degradation vs. resin fouling) on column performance over lifetime of the most commonly used alkali-stable Protein A resins (MabSelect SuRe and MabSelect SuRe LX). The change in binding capacity as a function of sodium hydroxide concentration (rate of hydrolysis), temperature, and stabilizing additives was examined. Additionally, resin extraction studies and product cycling studies were conducted to determine cleaning effectiveness (resin fouling) of various cleaning strategies. Sodium hydroxide-based cleaning solutions were shown to be more effective at preventing resin fouling. Conversely, cold temperature and the use of stabilizing additives in conjunction with sodium hydroxide were found to be beneficial in minimizing the rate of Protein A ligand hydrolysis. An effective and robust cleaning strategy is presented here to maximize resin lifetime and thereby the number of column cycles for future manufacturing processes. © 2017 American Institute of Chemical Engineers Biotechnol. Prog., 33:708-715, 2017. © 2017 American Institute of Chemical Engineers.

  1. Ballistic stretch or aerobic warm-up evoke postexercise hypotension after maximal exercise

    Directory of Open Access Journals (Sweden)

    Raoni Conceição Dos-Santos

    2017-11-01

    Full Text Available DOI: http://dx.doi.org/10.5007/1980-0037.2017v19n4p416   Warm-up is broadly used to increase performance and protect against injury in sports. However, the effects of different models of warm-up on maximal exercise and the subsequent recovery period are undetermined. This study aimed to assess the effects of different warm-ups on performance, blood pressure and autonomic control. Fifity three subjects rested for 5 minutes and then were randomly allocated to one of four experimental groups: Control (CTR, Aerobic Warm-up (AER, Static (SST or Ballistic (BST stretch. Immediately after warm-up, they performed a maximal cycling test and rested for 30 minutes. Heart rate variability (HRV, Systolic (SBP and diastolic (DBP blood pressure were assessed throughout the entire experiment. Statistical analysis was performed by one-way ANOVA with Tukey post-test or two-way ANOVA followed by either Bonferroni or Dunnet post-test, when appropriate. Warm-up did not change test performance or HRV (p>.05, however, when compared between-groups, SBP was higher in BST against all groups (p.05. When compared to baseline values SST showed increased SBP in recovery (p<.05 while only AER and BST showed post-exercise hypotension at 30 minutes (p<.05. In conclusion, despite the lack of effects on performance, AER and BST seem to improve while SST seems to impair the recovery of cardiovascular parameters in an autonomic-independent mechanism.

  2. An expectation/maximization nuclear vector replacement algorithm for automated NMR resonance assignments

    International Nuclear Information System (INIS)

    Langmead, Christopher James; Donald, Bruce Randall

    2004-01-01

    We report an automated procedure for high-throughput NMR resonance assignment for a protein of known structure, or of an homologous structure. Our algorithm performs Nuclear Vector Replacement (NVR) by Expectation/Maximization (EM) to compute assignments. NVR correlates experimentally-measured NH residual dipolar couplings (RDCs) and chemical shifts to a given a priori whole-protein 3D structural model. The algorithm requires only uniform 15 N-labelling of the protein, and processes unassigned H N - 15 N HSQC spectra, H N - 15 N RDCs, and sparse H N -H N NOE's (d NN s). NVR runs in minutes and efficiently assigns the (H N , 15 N) backbone resonances as well as the sparse d NN s from the 3D 15 N-NOESY spectrum, in O(n 3 ) time. The algorithm is demonstrated on NMR data from a 76-residue protein, human ubiquitin, matched to four structures, including one mutant (homolog), determined either by X-ray crystallography or by different NMR experiments (without RDCs). NVR achieves an average assignment accuracy of over 99%. We further demonstrate the feasibility of our algorithm for different and larger proteins, using different combinations of real and simulated NMR data for hen lysozyme (129 residues) and streptococcal protein G (56 residues), matched to a variety of 3D structural models. Abbreviations: NMR, nuclear magnetic resonance; NVR, nuclear vector replacement; RDC, residual dipolar coupling; 3D, three-dimensional; HSQC, heteronuclear single-quantum coherence; H N , amide proton; NOE, nuclear Overhauser effect; NOESY, nuclear Overhauser effect spectroscopy; d NN , nuclear Overhauser effect between two amide protons; MR, molecular replacement; SAR, structure activity relation; DOF, degrees of freedom; nt., nucleotides; SPG, Streptococcal protein G; SO(3), special orthogonal (rotation) group in 3D; EM, Expectation/Maximization; SVD, singular value decomposition

  3. Consumer preferences for alternative fuel vehicles: Comparing a utility maximization and a regret minimization model

    International Nuclear Information System (INIS)

    Chorus, Caspar G.; Koetse, Mark J.; Hoen, Anco

    2013-01-01

    This paper presents a utility-based and a regret-based model of consumer preferences for alternative fuel vehicles, based on a large-scale stated choice-experiment held among company car leasers in The Netherlands. Estimation and application of random utility maximization and random regret minimization discrete choice models shows that while the two models achieve almost identical fit with the data and differ only marginally in terms of predictive ability, they generate rather different choice probability-simulations and policy implications. The most eye-catching difference between the two models is that the random regret minimization model accommodates a compromise-effect, as it assigns relatively high choice probabilities to alternative fuel vehicles that perform reasonably well on each dimension instead of having a strong performance on some dimensions and a poor performance on others. - Highlights: • Utility- and regret-based models of preferences for alternative fuel vehicles. • Estimation based on stated choice-experiment among Dutch company car leasers. • Models generate rather different choice probabilities and policy implications. • Regret-based model accommodates a compromise-effect

  4. Intraperitoneal administration of docosahexaenoic acid for 14days increases serum unesterified DHA and seizure latency in the maximal pentylenetetrazol model.

    Science.gov (United States)

    Trépanier, Marc-Olivier; Lim, Joonbum; Lai, Terence K Y; Cho, Hye Jin; Domenichiello, Anthony F; Chen, Chuck T; Taha, Ameer Y; Bazinet, Richard P; Burnham, W M

    2014-04-01

    Docosahexaenoic acid (DHA) is an omega-3 polyunsaturated fatty acid (n-3 PUFA) which has been shown to raise seizure thresholds following acute administration in rats. The aims of the present experiment were the following: 1) to test whether subchronic DHA administration raises seizure threshold in the maximal pentylenetetrazol (PTZ) model 24h following the last injection and 2) to determine whether the increase in seizure threshold is correlated with an increase in serum and/or brain DHA. Animals received daily intraperitoneal (i.p.) injections of 50mg/kg of DHA, DHA ethyl ester (DHA EE), or volume-matched vehicle (albumin/saline) for 14days. On day 15, one subset of animals was seizure tested in the maximal PTZ model (Experiment 1). In a separate (non-seizure tested) subset of animals, blood was collected, and brains were excised following high-energy, head-focused microwave fixation. Lipid analysis was performed on serum and brain (Experiment 2). For data analysis, the DHA and DHA EE groups were combined since they did not differ significantly from each other. In the maximal PTZ model, DHA significantly increased seizure latency by approximately 3-fold as compared to vehicle-injected animals. This increase in seizure latency was associated with an increase in serum unesterified DHA. Total brain DHA and brain unesterified DHA concentrations, however, did not differ significantly in the treatment and control groups. An increase in serum unesterified DHA concentration reflecting increased flux of DHA to the brain appears to explain changes in seizure threshold, independent of changes in brain DHA concentrations. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. Reliability of surface electromyography activity of gluteal and hamstring muscles during sub-maximal and maximal voluntary isometric contractions.

    Science.gov (United States)

    Bussey, Melanie D; Aldabe, Daniela; Adhia, Divya; Mani, Ramakrishnan

    2018-04-01

    Normalizing to a reference signal is essential when analysing and comparing electromyography signals across or within individuals. However, studies have shown that MVC testing may not be as reliable in persons with acute and chronic pain. The purpose of this study was to compare the test-retest reliability of the muscle activity in the biceps femoris and gluteus maximus between a novel sub-MVC and standard MVC protocols. This study utilized a single individual repeated measures design with 12 participants performing multiple trials of both the sub-MVC and MVC tasks on two separate days. The participant position in the prone leg raise task was standardised with an ultrasonic sensor to improve task precession between trials/days. Day-to-day and trial-to-trial reliability of the maximal muscle activity was examined using ICC and SEM. Day-to-day and trial-to-trial reliability of the EMG activity in the BF and GM were high (0.70-0.89) to very high (≥0.90) for both test procedures. %SEM was <5-10% for both tests on a given day but higher in the day-to-day comparisons. The lower amplitude of the sub-MVC is a likely contributor to increased %SEM (8-13%) in the day-to-day comparison. The findings show that the sub-MVC modified prone double leg raise results in GM and BF EMG measures similar in reliability and precision to the standard MVC tasks. Therefore, the modified prone double leg raise may be a useful substitute for traditional MVC testing for normalizing EMG signals of the BF and GM. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. The effects of circadian rhythmicity of salivary cortisol and testosterone on maximal isometric force, maximal dynamic force, and power output.

    Science.gov (United States)

    Teo, Weipeng; McGuigan, Michael R; Newton, Michael J

    2011-06-01

    The study investigated the effects of circadian rhythm of cortisol (C) and testosterone (T) on maximal force production (Fpeak) and power output (Ppeak). Twenty male university students (mean age = 23.8 ± 3.6 years, height = 177.5 ± 6.4 cm, weight = 78.9 ± 11.2 kg) performed 4 time-of-day testing sessions consisting of countermovement jumps (CMJs), squat jumps (SJ), isometric midthigh pulls (IMTPs), and a 1-repetition maximum (1RM) squat. Saliva samples were collected at 0800, 1200, 1600, and 2000 hours to assess T and C levels on each testing day. Session rate-of-perceived exertion (RPE) scores were collected after each session. The results showed that Fpeak and Ppeak presented a clear circadian rhythm in CMJ and IMTP but not in SJ. One repetition maximum squat did not display a clear circadian rhythm. Session RPE scores collected at 0800 and 2000 hours were significantly (p ≤ 0.05) higher than those obtained at 1200 and 1600 hours. Salivary T and C displayed a clear circadian rhythm with highest values at 0800 hours and lowest at 2000 hours; however, no significant correlation was found between T and C with Fpeak and Ppeak. A very strong correlation was found between Taural with Fpeak of CMJ and IMTP and Ppeak of CMJ (r = 0.86, r = 0.84 and r = 0.8, p ≤ 0.001). The study showed the existence of a circadian rhythm in Fpeak and Ppeak in CMJ and IMTP. The evidence suggests that strength and power training or testing should be scheduled later during the day. The use of Taural seemed to be a more effective indicator of physical performance than hormonal measures, and the use of session RPE should also be closely monitored because it may present a circadian rhythm.

  7. The effect of a high carbohydrate diet and glycogen depletion on graded maximal exercise

    OpenAIRE

    小林, 義雄; 細井, 輝男; 竹内, 敏子; 朴, 哲浩; 金, 享烈; 荒井, 康夫; Yoshio, Kobayashi; Teruo, Hosoi; Toshiko, Takeuchi; Cheol-Ho, Pak; Hyung-Ryul, Kim; Yasuo, Arai; 中京大学教養部健康スポーツ科学研究室; 中京大学教養部健康スポーツ科学研究室; 中京大学教養部健康スポーツ科学研究室

    1997-01-01

    The present investigation examined the influence of dietary carbohydrate (CHO) on the performance of graded maximal exercise on a bicycle ergometer. A group of highly trained college students [mean age 22.2 (SD 1.6) years] completed three trials of graded maximal exercise under three dietary conditions; normal diet (ND), glycogen depleted (CHD), and glycogen loaded (CHL) conditions with each trial separated by five days. Measurements of work done, maximal oxygen intake (Vo_), serum lactae, gl...

  8. Maximizing Immune Response to Carbohydrate Antigens on Breast Tumors

    Science.gov (United States)

    2005-08-01

    is dependent on the chemical structure Cellular responses to carbohydrates 1369 of the glycan as well as its position within a peptide. Glycopep...M., Dang, K., 45 Bruehl, R. E., Bertozzi, C. R. and Rosen, S. D. 2000. Minimal Wang, B., Boyer, J. and Weiner, D. 1997. In vivo engineering of a...purified by Thyl.2-coated beads. Purified T cells were tested for ’- purity as >97% positive for anfi -CD3 antibody. For cell transfer experiments, FLI"H

  9. Searching for an Academic Librarian Job: Techniques to Maximize Success

    OpenAIRE

    Angela R. Davis

    2015-01-01

    Job-hunting can be a confusing process for new librarians searching for their first professional position. Much of the literature available to potential job seekers focuses on general interview etiquette. This article provides advice to expedite the job hunt for academic library positions. The author draws upon personal experience to provide tips for an effective job hunt. These include how to prepare for a job search, locate job announcements, prepare application materials, typical interview...

  10. Maximize O ampersand M effectiveness with creative engineering, common sense

    International Nuclear Information System (INIS)

    Bretz, E.A.

    1994-01-01

    Typically, powerplant operations and maintenance (O ampersand M) practices are governed by three things: policies of the owner/operator and regulatory authorities; the type of equipment in place; and the level of experience in the engineering, operations, and maintenance departments at both the plant and the electric utility's headquarters staff. Yet, regardless of the type of plant involved - nuclear, hydroelectric, gas-turbine-based, fossil-fired steam/electric - creative engineering coupled with common sense provides the backdrop of many, if not most, solutions to O ampersand M problems. Some examples of creative engineering are cited. 3 figs

  11. The effects of three days of sub-maximal-intensity mountain biking ...

    African Journals Online (AJOL)

    The effects of three days of sub-maximal-intensity mountain biking on sleep. SP Murphy, A Fuller, AJ Bentley, I Avidon. Abstract. Objectives. We determined the effect of three consecutive days of sub-maximal-intensity mountain biking (4.5 hours per day, ~64 km per day), on the sleep of ten healthy, trained male and female ...

  12. Weighted and vector-valued inequalities for one-sided maximal

    Indian Academy of Sciences (India)

    In this paper, we study weighted and vector-valued inequalities for one-sided maximal functions. In particular, we give a new proof of l r -valued extension of weighted L p -inequalities for one-sided maximal functions. In the process, we prove an analogue of the well-known Fefferman–Stein's weighted lemma in the context ...

  13. Maximal airway narrowing in humans in vivo. Histamine compared with methacholine

    NARCIS (Netherlands)

    Sterk, P. J.; Timmers, M. C.; Dijkman, J. H.

    1986-01-01

    Maximal airway narrowing to inhaled nonsensitizing stimuli is limited to a mild degree in nonasthmatic and mildly asthmatic subjects. We investigated whether this limitation is due to a nonspecific inhibitory mechanism (with regard to the agonist) by comparing the maximal response plateaus of

  14. Active Female Maximal and Anaerobic Threshold Cardiorespiratory Responses to Six Different Water Aerobics Exercises

    Science.gov (United States)

    Antunes, Amanda H.; Alberton, Cristine L.; Finatto, Paula; Pinto, Stephanie S.; Cadore, Eduardo L.; Zaffari, Paula; Kruel, Luiz F. M.

    2015-01-01

    Purpose: Maximal tests conducted on land are not suitable for the prescription of aquatic exercises, which makes it difficult to optimize the intensity of water aerobics classes. The aim of the present study was to evaluate the maximal and anaerobic threshold cardiorespiratory responses to 6 water aerobics exercises. Volunteers performed 3 of the…

  15. Deconstructing facts and frames in energy research: Maxims for evaluating contentious problems

    International Nuclear Information System (INIS)

    Sovacool, Benjamin K.; Brown, Marilyn A.

    2015-01-01

    In this article, we argue that assumptions and values can play a combative, corrosive role in the generation of objective energy analysis. We then propose six maxims for energy analysts and researchers. Our maxim of information asks readers to keep up to date on trends in energy resources and technology. Our maxim of inclusivity asks readers to involve citizens and other public actors more in energy decisions. Our maxim of symmetry asks readers to keep their analysis of energy technologies centered always on both technology and society. Our maxim of reflexivity asks readers to be self-aware of one's assumptions. Our maxim of prudence asks readers to make energy decisions that are ethical or at least informed. Our maxim of agnosticism asks readers to look beyond a given energy technology to the services it provides and recognize that many systems can provide a desired service. We conclude that decisions in energy are justified by, if not predicated on, beliefs—beliefs which may or may not be supported by objective data, constantly blurring the line between fact, fiction, and frames. - Highlights: • Assumptions and values can play a combative, corrosive role in the generation of objective energy analysis. • Decisions in energy are justified by, if not predicated on, beliefs. • We propose six maxims for energy analysts and researcher.

  16. Conversational Implicature of Peanuts Comic Strip Based on Grice’s Maxim Theory

    Directory of Open Access Journals (Sweden)

    Muhartoyo Muhartoyo

    2013-04-01

    Full Text Available This article discusses about conversational implicature that occurs in Peanuts comic strips. The objectives of this study are to find out the implied meaning in the conversation between Charlie Brown with Lucy van Pelt and Lucy van Pelt with Linus van Pelt to evaluate the existence of maxim flouting and maxim violating in those conversations in relation to the four maxims such as quantity, quality, relation, and manner. Likewise, this study attempts to find out the reason for using conversational implicature in a comic strip. The writers uses a qualitative method with library research concerning to Grice’s maxim theory to analyze the conversational implicature. Based on the analysis, it can be concluded that all the comics that comprise 14 comics generate conversational implicature since all the characters breach rules of maxim. The result of this analysis shows that flouting maxim of manner has the highest occurrence of conversational implicature and the least occurrences belong to flouting maxim of relation and violating maxim of quantity. Moreover, the writers concludes that to make a successful communication ideally the speaker and the hearer to cooperate in the conversation by saying explicitly so the hearer can grasp the meaning as the goal of communication is to deliver a message to the hearer.  

  17. Cardio-Respiratory Responses to Maximal Work During Arm and Bicycle Ergometry.

    Science.gov (United States)

    Israel, Richard G.; Hardison, George T.

    This study compared cardio-respiratory responses during maximal arm work using a Monarch Model 880 Rehab Trainer to cardio-respiratory responses during maximal leg work on a Monarch Model 850 Bicycle Ergometer. Subjects for the investigation were 17 male university students ranging from 18 to 28 years of age. The specific variables compared…

  18. Nonlinear Impairment Compensation Using Expectation Maximization for PDM 16-QAM Systems

    DEFF Research Database (Denmark)

    Zibar, Darko; Winther, Ole; Franceschi, Niccolo

    2012-01-01

    We show experimentally that by using non-linear signal processing based algorithm, expectation maximization, nonlinear system tolerance can be increased by 2 dB. Expectation maximization is also effective in combating I/Q modulator nonlinearities and laser linewidth....

  19. Non-maximizing output behavior for firms with a cost-constrained technology

    NARCIS (Netherlands)

    Blank, J.L.T.

    2008-01-01

    In many public service industries, firms are constrained by a cost (budget) and characterized by non-maximizing output behavior, due to bureaucratic behavior, for instance. This paper proposes a model based on the assumption that firms with a cost constraint do not maximize service levels due to

  20. Maximizing carbon storage in the Appalachians: A method for considering the risk of disturbance events

    Science.gov (United States)

    Michael R. Vanderberg; Kevin Boston; John. Bailey

    2011-01-01

    Accounting for the probability of loss due to disturbance events can influence the prediction of carbon flux over a planning horizon, and can affect the determination of optimal silvicultural regimes to maximize terrestrial carbon storage. A preliminary model that includes forest disturbance-related carbon loss was developed to maximize expected values of carbon stocks...

  1. Is energy expenditure taken into account in human sub-maximal jumping? - a simulation study

    NARCIS (Netherlands)

    Vanrenterghem, J.; Bobbert, M.F.; Casius, L.J.R.; de Clercq, D.

    2008-01-01

    This paper presents a simulation study that was conducted to investigate whether the stereotyped motion pattern observed in human sub-maximal jumping can be interpreted from the perspective of energy expenditure. Human sub-maximal vertical countermovement jumps were compared to jumps simulated with

  2. St Maxim the Greek: Some notes on his understanding of the sacred time

    Directory of Open Access Journals (Sweden)

    Neža Zajc

    2016-10-01

    Full Text Available St Maxim the Greek: Some notes on his understanding of the sacred time Based on a manuscript by St Maxim the Greek, this article explores his specific under­standing of the relationship between language and biblical tradition. It gives some answers to questions concerning his theology, which are posed by his liturgical experience of the sacred time, which is based not on repeating the excerptions from the patristic authors, but is primarily founded on his accurate reading and in-depth perception of the Holy Bible. Maxim the Greek, who in his personal writings showed a detailed knowledge of both the Old Testament and Sla­vonic biblical texts, was thus not only able to separate the canonical from the non-canonical sacred texts, but also successfully classified the Christian teachings according to ethical value, from the Old Testament prophets to the apostles and the Church Fathers. With his hierarchy he also gave meaning to the ontological-eschatological dimension (three levels – appropriate to the Holy Trinity of their spiritual efforts. His knowledge, which also reflects the precise understanding of dogmatic theological decisions of the first ecumenical church councils, ranks highest the learning that comes directly from the Son of God, which Maxim the Greek experienced through his theological-liturgical prayer practice. Maxim found theologically unambiguous formulations which most profoundly deter­mined the specific nature of his personal theology in the Byzantine hymnography dedicated to the Mother of God. All the mentioned facts lead the author to the further explore his specific Old Church Slavonic language, in which he managed to preserve not only the early Christian mentality but also the theological-liturgical characteristics of the ascetic and later monastic discipline that he learned in the monastery of Vatopedi at the Holy Mount Athos. The article concludes with the proposition that only through detailed study of the personal

  3. Cryogenics for LHC experiments

    CERN Multimedia

    2001-01-01

    Cryogenic systems will be used by LHC experiments to maximize their performance. Institutes around the world are collaborating with CERN in the construction of these very low temperature systems. The cryogenic test facility in hall 180 for ATLAS magnets. High Energy Physics experiments have frequently adopted cryogenic versions of their apparatus to achieve optimal performance, and those for the LHC will be no exception. The two largest experiments for CERN's new flagship accelerator, ATLAS and CMS, will both use large superconducting magnets operated at 4.5 Kelvin - almost 270 degrees below the freezing point of water. ATLAS also includes calorimeters filled with liquid argon at 87 Kelvin. For the magnets, the choice of a cryogenic version was dictated by a combination economy and transparency to emerging particles. For the calorimeters, liquid argon was selected as the fluid best suited to the experiment's physics requirements. High Energy Physics experiments are the result of worldwide collaborations and...

  4. OMEGA laser-driven hydrodynamic plasma jet experiments with relevance to astrophysics

    Science.gov (United States)

    Sublett, Stephanie L.

    2008-06-01

    Plasma jets are ubiquitous consequences of stellar and galactic evolution. Well resolved astronomical jets are observed to have numerous internal shock wave structures [1]. There is great interest in determining the origins of these structures. The initial conditions and early evolution of outflows cannot be observed by current telescopes because of resolution limits or obscuration from the relatively dense gas and dust close to the jet source. By the time a jet is discernible, it has usually propagated many jet radii from its source. Laboratory experiments provide the only direct probe of the early hydrodynamic stages of jet evolution. The plasma jet experiments described in this thesis were performed on the University of Rochester's OMEGA laser [2], using various drive configurations. Single pulsed jets are created by one set of laser beams. Double pulsed jets are created by two sets of laser beams separated in time. Single pulsed jets were generated with the same laser beams as either one set or both sets used to generate the double pulsed jets. The comparison of the two types of jets is being carried out for the first time. Quantitative comparisons between astrophysical models and experimental data show that an adaibatic astrophysical jet model [3] provides a better fit to jet bow shock profiles and internal jet features than a momentum-driven model [4]. Jet sizes at a given age were consistent with the energy-driven model. The OMEGA laser experiments created millimeter-sized hydrodynamic plasma jets with velocities, energy densities, and jet-to-ambient density contrasts relevant to astronomical jets. The bow shock profiles of the experimental jets are fit by a ballistic bow shock model, distinguishing them as adaibatic jets. These jet experiments provide the first laboratory test of the adiabatic model in reference [3] and extend the applicable regime of impulsive, adiabatic jet simulations to higher density contrasts.

  5. Maximal heart rate does not limit cardiovascular capacity in healthy humans

    DEFF Research Database (Denmark)

    Munch, G D W; Svendsen, J H; Damsgaard, R

    2014-01-01

    In humans, maximal aerobic power (VO2 max ) is associated with a plateau in cardiac output (Q), but the mechanisms regulating the interplay between maximal heart rate (HRmax) and stroke volume (SV) are unclear. To evaluate the effect of tachycardia and elevations in HRmax on cardiovascular function...... and RAP (P human heart can be paced to a higher HR than observed during maximal exercise, suggesting that HRmax and myocardial work capacity do not limit VO2 max in healthy...... and capacity during maximal exercise in healthy humans, 12 young male cyclists performed incremental cycling and one-legged knee-extensor exercise (KEE) to exhaustion with and without right atrial pacing to increase HR. During control cycling, Q and leg blood flow increased up to 85% of maximal workload (WLmax...

  6. Comparison of changes in the mobility of the pelvic floor muscle on during the abdominal drawing-in maneuver, maximal expiration, and pelvic floor muscle maximal contraction

    Science.gov (United States)

    Jung, Halim; Jung, Sangwoo; Joo, Sunghee; Song, Changho

    2016-01-01

    [Purpose] The purpose of this study was to compare changes in the mobility of the pelvic floor muscle during the abdominal drawing-in maneuver, maximal expiration, and pelvic floor muscle maximal contraction. [Subjects] Thirty healthy adults participated in this study (15 men and 15 women). [Methods] All participants performed a bridge exercise and abdominal curl-up during the abdominal drawing-in maneuver, maximal expiration, and pelvic floor muscle maximal contraction. Pelvic floor mobility was evaluated as the distance from the bladder base using ultrasound. [Results] According to exercise method, bridge exercise and abdominal curl-ups led to significantly different pelvic floor mobility. The pelvic floor muscle was elevated during the abdominal drawing-in maneuver and descended during maximal expiration. Finally, pelvic floor muscle mobility was greater during abdominal curl-up than during the bridge exercise. [Conclusion] According to these results, the abdominal drawing-in maneuver induced pelvic floor muscle contraction, and pelvic floor muscle contraction was greater during the abdominal curl-up than during the bridge exercise. PMID:27065532

  7. Effect of Maximal Versus Supra-Maximal Exhausting Race on Lipid Peroxidation, Antioxidant Activity and Muscle-Damage Biomarkers in Long-Distance and Middle-Distance Runners.

    Science.gov (United States)

    Mohamed, Said; Lamya, Ncir; Hamda, Mansour

    2016-03-01

    Exhausting physical exercise increases lipid peroxidation and causes important muscle damages. The human body tries to mitigate these adverse effects by mobilizing its antioxidant defenses. This study aims to investigate the effect of a maximal versus supra-maximal race sustained until exhaustion on lipid peroxidation, antioxidant activity and muscle-damage biomarkers in trained (i.e. long-distance and middle-distance runners) and sedentary subjects. The study has been carried out on 8 middle-distance runners (MDR), 9 long-distance runners (LDR), and 8 sedentary subjects (SS). Each subject has undergone two exhaustive running tests, the first one is an incremental event (VAMEVAL test), the second one is a constant supra-maximal intensity test (limited-time test). Blood samples were collected at rest and immediately after each test. A significant increase in malondialdehyde (MDA) concentrations was observed in SS and MDR after the VAMEVAL test and in LDR after the Limited-Time test. A significant difference was also observed between LDR and the other two groups after the VAMEVAL test, and between LDR and MDR after the Limited-Time test. Significant modifications, notably, in myoglobin, CK, LDH, IL-6, TNF-α, and TAS were likewise noted but depending on the race-type and the sportive specialty. Maximal and supra-maximal races induce a significant increase in lipid peroxidation and cause non-negligible inflammation and muscle damage. These effects were relatively related to the physical exercise type and the sportive specialty.

  8. Comparison of changes in the mobility of the pelvic floor muscle on during the abdominal drawing-in maneuver, maximal expiration, and pelvic floor muscle maximal contraction.

    Science.gov (United States)

    Jung, Halim; Jung, Sangwoo; Joo, Sunghee; Song, Changho

    2016-01-01

    [Purpose] The purpose of this study was to compare changes in the mobility of the pelvic floor muscle during the abdominal drawing-in maneuver, maximal expiration, and pelvic floor muscle maximal contraction. [Subjects] Thirty healthy adults participated in this study (15 men and 15 women). [Methods] All participants performed a bridge exercise and abdominal curl-up during the abdominal drawing-in maneuver, maximal expiration, and pelvic floor muscle maximal contraction. Pelvic floor mobility was evaluated as the distance from the bladder base using ultrasound. [Results] According to exercise method, bridge exercise and abdominal curl-ups led to significantly different pelvic floor mobility. The pelvic floor muscle was elevated during the abdominal drawing-in maneuver and descended during maximal expiration. Finally, pelvic floor muscle mobility was greater during abdominal curl-up than during the bridge exercise. [Conclusion] According to these results, the abdominal drawing-in maneuver induced pelvic floor muscle contraction, and pelvic floor muscle contraction was greater during the abdominal curl-up than during the bridge exercise.

  9. The key kinematic determinants of undulatory underwater swimming at maximal velocity.

    Science.gov (United States)

    Connaboy, Chris; Naemi, Roozbeh; Brown, Susan; Psycharakis, Stelios; McCabe, Carla; Coleman, Simon; Sanders, Ross

    2016-01-01

    The optimisation of undulatory underwater swimming is highly important in competitive swimming performance. Nineteen kinematic variables were identified from previous research undertaken to assess undulatory underwater swimming performance. The purpose of the present study was to determine which kinematic variables were key to the production of maximal undulatory underwater swimming velocity. Kinematic data at maximal undulatory underwater swimming velocity were collected from 17 skilled swimmers. A series of separate backward-elimination analysis of covariance models was produced with cycle frequency and cycle length as dependent variables (DVs) and participant as a fixed factor, as including cycle frequency and cycle length would explain 100% of the maximal swimming velocity variance. The covariates identified in the cycle-frequency and cycle-length models were used to form the saturated model for maximal swimming velocity. The final parsimonious model identified three covariates (maximal knee joint angular velocity, maximal ankle angular velocity and knee range of movement) as determinants of the variance in maximal swimming velocity (adjusted-r2 = 0.929). However, when participant was removed as a fixed factor there was a large reduction in explained variance (adjusted r2 = 0.397) and only maximal knee joint angular velocity continued to contribute significantly, highlighting its importance to the production of maximal swimming velocity. The reduction in explained variance suggests an emphasis on inter-individual differences in undulatory underwater swimming technique and/or anthropometry. Future research should examine the efficacy of other anthropometric, kinematic and coordination variables to better understand the production of maximal swimming velocity and consider the importance of individual undulatory underwater swimming techniques when interpreting the data.

  10. Flouting maxim by sherlock holmes and dr. Watson in tv series Of sherlock season

    Directory of Open Access Journals (Sweden)

    Lina Affifatusholihah

    2017-04-01

    In running daily activities, people will always meet and interact with other people, and language is a medium that is used by humans to interact with each other. In a conversation or discussion, everyone should pay attention to the four maxims in order that there are no errors in communication. However, it is not uncommon that the four rules above are breached by the speakers. This is called non-observance of the maxims, and one of a non-observance of the maxims that often occurs in is flouting maxim. The aims of this paper are to describe types of maxims that are flouted by Sherlock Holmes and dr. Watson as well as to describe how the maxims are flouted in Sherlock TV series season 1. This research used qualitative descriptive method. The researcher classifies the utterances to know what kind of maxim which are flouted, categorizes those into the category based on the Grice’s theory of Cooperative Principle, namely: maxim of quantity, quality, relation and manner. The research procedure begin by searching the script in the internet, matching the utterances in the script and in film and sorting the utterances between Sherlock Holmes and dr. Watson as well observing every word or sentence which are flouted by the main characters. The findings find that all kinds of maxims are flouted by Sherlock and dr. Watson. The result of analysis shows that the maxim flouted when the speakers say something irrelevant; something roguishness or lied to hide the truth in the form of rhetorical question; the information becomes more or too informative than what is required; and something obscurity of expression, ambiguity, or unnecessary prolixity.

  11. Entropy-rate clustering: cluster analysis via maximizing a submodular function subject to a matroid constraint.

    Science.gov (United States)

    Liu, Ming-Yu; Tuzel, Oncel; Ramalingam, Srikumar; Chellappa, Rama

    2014-01-01

    We propose a new objective function for clustering. This objective function consists of two components: the entropy rate of a random walk on a graph and a balancing term. The entropy rate favors formation of compact and homogeneous clusters, while the balancing function encourages clusters with similar sizes and penalizes larger clusters that aggressively group samples. We present a novel graph construction for the graph associated with the data and show that this construction induces a matroid--a combinatorial structure that generalizes the concept of linear independence in vector spaces. The clustering result is given by the graph topology that maximizes the objective function under the matroid constraint. By exploiting the submodular and monotonic properties of the objective function, we develop an efficient greedy algorithm. Furthermore, we prove an approximation bound of (1/2) for the optimality of the greedy solution. We validate the proposed algorithm on various benchmarks and show its competitive performances with respect to popular clustering algorithms. We further apply it for the task of superpixel segmentation. Experiments on the Berkeley segmentation data set reveal its superior performances over the state-of-the-art superpixel segmentation algorithms in all the standard evaluation metrics.

  12. A constrained maximization formulation to analyze deformation of fiber reinforced elastomeric actuators

    Science.gov (United States)

    Singh, Gaurav; Krishnan, Girish

    2017-06-01

    Fiber reinforced elastomeric enclosures (FREEs) are soft and smart pneumatic actuators that deform in a predetermined fashion upon inflation. This paper analyzes the deformation behavior of FREEs by formulating a simple calculus of variations problem that involves constrained maximization of the enclosed volume. The model accurately captures the deformed shape for FREEs with any general fiber angle orientation, and its relation with actuation pressure, material properties and applied load. First, the accuracy of the model is verified with existing literature and experiments for the popular McKibben pneumatic artificial muscle actuator with two equal and opposite families of helically wrapped fibers. Then, the model is used to predict and experimentally validate the deformation behavior of novel rotating-contracting FREEs, for which no prior literature exist. The generality of the model enables conceptualization of novel FREEs whose fiber orientations vary arbitrarily along the geometry. Furthermore, the model is deemed to be useful in the design synthesis of fiber reinforced elastomeric actuators for general axisymmetric desired motion and output force requirement.

  13. On the Shoulders of Giants: Incremental Influence Maximization in Evolving Social Networks

    Directory of Open Access Journals (Sweden)

    Xiaodong Liu

    2017-01-01

    Full Text Available Influence maximization problem aims to identify the most influential individuals so as to help in developing effective viral marketing strategies over social networks. Previous studies mainly focus on designing efficient algorithms or heuristics on a static social network. As a matter of fact, real-world social networks keep evolving over time and a recalculation upon the changed network inevitably leads to a long running time. In this paper, we propose an incremental approach, IncInf, which can efficiently locate the top-K influential individuals in evolving social networks based on previous information instead of calculation from scratch. In particular, IncInf quantitatively analyzes the influence spread changes of nodes by localizing the impact of topology evolution to only local regions, and a pruning strategy is further proposed to narrow the search space into nodes experiencing major increases or with high degrees. To evaluate the efficiency and effectiveness, we carried out extensive experiments on real-world dynamic social networks: Facebook, NetHEPT, and Flickr. Experimental results demonstrate that, compared with the state-of-the-art static algorithm, IncInf achieves remarkable speedup in execution time while maintaining matching performance in terms of influence spread.

  14. Research on Adaptive Optics Image Restoration Algorithm by Improved Expectation Maximization Method

    Directory of Open Access Journals (Sweden)

    Lijuan Zhang

    2014-01-01

    Full Text Available To improve the effect of adaptive optics images’ restoration, we put forward a deconvolution algorithm improved by the EM algorithm which joints multiframe adaptive optics images based on expectation-maximization theory. Firstly, we need to make a mathematical model for the degenerate multiframe adaptive optics images. The function model is deduced for the points that spread with time based on phase error. The AO images are denoised using the image power spectral density and support constraint. Secondly, the EM algorithm is improved by combining the AO imaging system parameters and regularization technique. A cost function for the joint-deconvolution multiframe AO images is given, and the optimization model for their parameter estimations is built. Lastly, the image-restoration experiments on both analog images and the real AO are performed to verify the recovery effect of our algorithm. The experimental results show that comparing with the Wiener-IBD or RL-IBD algorithm, our iterations decrease 14.3% and well improve the estimation accuracy. The model distinguishes the PSF of the AO images and recovers the observed target images clearly.

  15. An iterative reconstruction method of complex images using expectation maximization for radial parallel MRI

    International Nuclear Information System (INIS)

    Choi, Joonsung; Kim, Dongchan; Oh, Changhyun; Han, Yeji; Park, HyunWook

    2013-01-01

    In MRI (magnetic resonance imaging), signal sampling along a radial k-space trajectory is preferred in certain applications due to its distinct advantages such as robustness to motion, and the radial sampling can be beneficial for reconstruction algorithms such as parallel MRI (pMRI) due to the incoherency. For radial MRI, the image is usually reconstructed from projection data using analytic methods such as filtered back-projection or Fourier reconstruction after gridding. However, the quality of the reconstructed image from these analytic methods can be degraded when the number of acquired projection views is insufficient. In this paper, we propose a novel reconstruction method based on the expectation maximization (EM) method, where the EM algorithm is remodeled for MRI so that complex images can be reconstructed. Then, to optimize the proposed method for radial pMRI, a reconstruction method that uses coil sensitivity information of multichannel RF coils is formulated. Experiment results from synthetic and in vivo data show that the proposed method introduces better reconstructed images than the analytic methods, even from highly subsampled data, and provides monotonic convergence properties compared to the conjugate gradient based reconstruction method. (paper)

  16. The Coming Nuclear Renaissance for Next Generation Safeguards Specialists--Maximizing Potential and Minimizing the Risks

    Energy Technology Data Exchange (ETDEWEB)

    Eipeldauer, Mary D [ORNL

    2009-01-01

    This document is intended to provide an overview of the workshop entitled 'The Coming Nuclear Renaissance for the Next Generation Safeguards Experts-Maximizing Benefits While Minimizing Proliferation Risks', conducted at Oak Ridge National Laboratory (ORNL) in partnership with the Y-12 National Security Complex (Y-12) and the Savannah River National Laboratory (SRNL). This document presents workshop objectives; lists the numerous participant universities and individuals, the nuclear nonproliferation lecture topics covered, and the facilities tours taken as part of the workshop; and discusses the university partnership sessions and proposed areas for collaboration between the universities and ORNL for 2009. Appendix A contains the agenda for the workshop; Appendix B lists the workshop attendees and presenters with contact information; Appendix C contains graphics of the evaluation form results and survey areas; and Appendix D summarizes the responses to the workshop evaluation form. The workshop was an opportunity for ORNL, Y-12, and SRNL staff with more than 30 years combined experience in nuclear nonproliferation to provide a comprehensive overview of their expertise for the university professors and their students. The overall goal of the workshop was to emphasize nonproliferation aspects of the nuclear fuel cycle and to identify specific areas where the universities and experts from operations and national laboratories could collaborate.

  17. Activity-Driven Influence Maximization in Social Networks

    DEFF Research Database (Denmark)

    Kumar, Rohit; Saleem, Muhammad Aamir; Calders, Toon

    2017-01-01

    Interaction networks consist of a static graph with a timestamped list of edges over which interaction took place. Examples of interaction networks are social networks whose users interact with each other through messages or location-based social networks where people interact by checking......-driven approach based on the identification of influence propagation patterns. In the first work, we identify so-called information-channels to model potential pathways for information spread, while the second work exploits how users in a location-based social network check in to locations in order to identify...... influential locations. To make our algorithms scalable, approximate versions based on sketching techniques from the data streams domain have been developed. Experiments show that in this way it is possible to efficiently find good seed sets for influence propagation in social networks....

  18. Maximizing ship-to-shore connections via telepresence technologies

    Science.gov (United States)

    Fundis, A. T.; Kelley, D. S.; Proskurowski, G.; Delaney, J. R.

    2012-12-01

    Live connections to offshore oceanographic research via telepresence technologies enable onshore scientists, students, and the public to observe and participate in active research as it is happening. As part of the ongoing construction effort of the NSF's Ocean Observatories Initiative's cabled network, the VISIONS'12 expedition included a wide breadth of activities to allow the public, students, and scientists to interact with a sea-going expedition. Here we describe our successes and lessons learned in engaging these onshore audiences through the various outreach efforts employed during the expedition including: 1) live high-resolution video and audio streams from the seafloor and ship; 2) live connections to science centers, aquaria, movie theaters, and undergraduate classrooms; 3) social media interactions; and 4) an onboard immersion experience for undergraduate and graduate students.

  19. Nurses' willingness to maximize opioid analgesia for severe cancer pain, and its predictor.

    Science.gov (United States)

    Chang, Yoon Jung; Yun, Young Ho; Park, Sang Min; Lee, So Woo; Park, Hyeoun-Ae; Ro, You-Ja; Huh, Bong Yul

    2005-09-01

    The effectiveness of cancer pain management (CPM) is influenced by nurses' willingness to maximize opioid analgesia for severe cancer pain. The purposes of this study were to identify the willingness of nurses to provide maximum-dose opioids whenever needed for CPM and to determine its associated predictors. This multicenter study was conducted among the entire total of registered nurses in seven large hospitals in Korea. Its overall response rate was 41.6%, and the data from 930 who responded (40.1%) were analyzed. We utilized a three-step, multidimensional, multiple logistic regression to identify the predictors of nurses' willingness. Only 255 nurses (27.4%) indicated that they recommended the maximum dose of opioids whenever it was needed. The respondents who were more likely to recommend morphine showed the following characteristics: older nurses (odds ratio, OR, 1.57; confidence interval, CI, 1.13-2.19); they knew the effectiveness of opioids for CPM (OR 1.53; CI 1.06-2.20); rarely concerned about a patient's addiction to opioids (OR 2.16; CI 1.48-3.15), or to a family member's addiction (OR 1.81; CI 1.20-2.73); prior experience with pain assessment tools (OR 1.62; CI 1.11-2.37); practical experience caring for cancer patients with pain over 51% (OR 1.55; CI 1.09-2.19). Our multicenter study suggested that in order to improve nurses' willingness to recommend opioids liberally in CPM: (1) attitudes about fear of opioid addiction must be changed; (2) the efficiency of opioids in CPM must be taught; and (3) implementation of pain assessment tools must be undertaken.

  20. Characterization of maximally random jammed sphere packings. III. Transport and electromagnetic properties via correlation functions

    Science.gov (United States)

    Klatt, Michael A.; Torquato, Salvatore

    2018-01-01

    In the first two papers of this series, we characterized the structure of maximally random jammed (MRJ) sphere packings across length scales by computing a variety of different correlation functions, spectral functions, hole probabilities, and local density fluctuations. From the remarkable structural features of the MRJ packings, especially its disordered hyperuniformity, exceptional physical properties can be expected. Here we employ these structural descriptors to estimate effective transport and electromagnetic properties via rigorous bounds, exact expansions, and accurate analytical approximation formulas. These property formulas include interfacial bounds as well as universal scaling laws for the mean survival time and the fluid permeability. We also estimate the principal relaxation time associated with Brownian motion among perfectly absorbing traps. For the propagation of electromagnetic waves in the long-wavelength limit, we show that a dispersion of dielectric MRJ spheres within a matrix of another dielectric material forms, to a very good approximation, a dissipationless disordered and isotropic two-phase medium for any phase dielectric contrast ratio. We compare the effective properties of the MRJ sphere packings to those of overlapping spheres, equilibrium hard-sphere packings, and lattices of hard spheres. Moreover, we generalize results to micro- and macroscopically anisotropic packings of spheroids with tensorial effective properties. The analytic bounds predict the qualitative trend in the physical properties associated with these structures, which provides guidance to more time-consuming simulations and experiments. They especially provide impetus for experiments to design materials with unique bulk properties resulting from hyperuniformity, including structural-color and color-sensing applications.

  1. Concomitant application of sprint and high-intensity interval training on maximal oxygen uptake and work output in well-trained cyclists.

    Science.gov (United States)

    Hebisz, Paulina; Hebisz, Rafał; Zatoń, Marek; Ochmann, Bartosz; Mielnik, Natalia

    2016-08-01

    In this study, we compared the effects of two different training modalities on maximal oxygen uptake and work output. Participants included 26 well-trained mountain bike cyclists were divided into two groups. The first group trained using a conventional endurance protocol at steady-state (moderate) intensity and variable-intensity (high-moderate-low) free of maximal efforts. The second group combined endurance training with a sprint and high-intensity interval training protocol, which, respectively, were based on 30 s maximal repetitions and 4 min high intensity repetitions. Training duration was 8 weeks. A graded exercise test was administered pre- and post-training. Work output, oxygen uptake, minute pulmonary ventilation, heart rate and stroke volume were determined during the test. While work output significantly increased post-training in both groups (P interval training group showed a greater magnitude of change (from 284.4 ± 91.9 to 314.2 ± 95.1 kJ) than the endurance training group (from 271.8 ± 73.3 to 283.4 ± 72.3 kJ). Significant increases in maximal oxygen uptake (from 57.9 ± 6.8 to 66.6 ± 5.3 ml kg(-1) min(-1)), maximal pulmonary ventilation and stroke volume were observed only in the interval training group. An exercise protocol involving endurance and sprint and high-intensity interval training was found to induce positive effects on maximal oxygen uptake in a group of well-trained cyclists with several years athletic experience.

  2. Maximizing Research Productivity and Recognition: Strategies for Junior Scientists

    Science.gov (United States)

    Bell, R. E.; Pfirman, S.; Culligan, P.; Laird, J.

    2007-12-01

    The post-doc and the first six years of the academic lifecycle are crucial: the performance and decisions a scientist makes during this time often set the stage for the rest of his or her career. We frame our presentation around the criteria that reviewers typically use to assess candidates: reputation, impact, and productivity. Publication productivity is one of the most critical aspects of a researcher's success and the number of publications is often the first item that evaluators look for when reviewing files of job applicants and tenure candidates. Citations are typically used as a measure of impact, but they reflect a complicated set of factors besides quality, for example, visibility, size of citing community, and integration in social and professional networks. Letters of recommendation carry significant weight in evaluations for promotion because they are the only external measure that synthesizes all three parameters: reputation, impact and productivity. We have developed strategies for developing a research plan, getting the most out of scientific meetings, identifying potential letter writers, and integrating research into teaching. In this presentation we combine insights from the literature with our own experiences, to outline these strategies for increasing research productivity, recognition, and impact.

  3. Preference-maximized nutrition planning by relative learning and ranking.

    Science.gov (United States)

    Hsiao, Jen-Hao

    2013-01-01

    Effective personal dietary guidelines are essential for health management and prevention of chronic diseases. A key factor toward a successful diet planning is an individual's food preference instead of dogmatic nutrition pattern since it is unlikely that an individual would accept the meal plan merely based on the nutrition supplements. However, the extraction of personal preference is definitely not a trivial matter. The objective of this research is to achieve nutrient-balanced food recommendations for each individual, while considering individual's preferences and requirements at the same time. To reach this goal, we present the k-relative learning technique for semi-automatically extracting users' preferences in a more efficient and effective manner. Comparing to conventional methods, the proposed system can not only reveal users' opinions about foods more fairly but also save lots of labeling efforts during the training data collection stage. In addition, a smarter feedback mechanism is also proposed to enable a more pleasant experience of the user-system interaction. The resulted system is thus expected to improve users' diet habit and compliance with healthier lifestyle.

  4. Dynamic cerebral autoregulation is acutely impaired during maximal apnoea in trained divers.

    Directory of Open Access Journals (Sweden)

    Troy J Cross

    Full Text Available AIMS: To examine whether dynamic cerebral autoregulation is acutely impaired during maximal voluntary apnoea in trained divers. METHODS: Mean arterial pressure (MAP, cerebral blood flow-velocity (CBFV and end-tidal partial pressures of O2 and CO2 (PETO2 and PETCO2 were measured in eleven trained, male apnoea divers (28 ± 2 yr; 182 ± 2 cm, 76 ± 7 kg during maximal "dry" breath holding. Dynamic cerebral autoregulation was assessed by determining the strength of phase synchronisation between MAP and CBFV during maximal apnoea. RESULTS: The strength of phase synchronisation between MAP and CBFV increased from rest until the end of maximal voluntary apnoea (P<0.05, suggesting that dynamic cerebral autoregulation had weakened by the apnoea breakpoint. The magnitude of impairment in dynamic cerebral autoregulation was strongly, and positively related to the rise in PETCO2 observed during maximal breath holding (R (2 = 0.67, P<0.05. Interestingly, the impairment in dynamic cerebral autoregulation was not related to the fall in PETO2 induced by apnoea (R (2 = 0.01, P = 0.75. CONCLUSIONS: This study is the first to report that dynamic cerebral autoregulation is acutely impaired in trained divers performing maximal voluntary apnoea. Furthermore, our data suggest that the impaired autoregulatory response is related to the change in PETCO2, but not PETO2, during maximal apnoea in trained divers.

  5. Physiological and subjective responses to maximal repetitive lifting employing stoop and squat technique.

    Science.gov (United States)

    Hagen, K B; Hallén, J; Harms-Ringdahl, K

    1993-01-01

    To establish safe levels for physical strain in occupational repetitive lifting, it is of interest to know the specific maximal working capacity. Power output, O2 consumption, heart rate and ventilation were measured in ten experienced forestry workers during maximal squat and stoop repetitive lifting. The two modes of repetitive lifting were also compared with maximal treadmill running. In addition, electromyogram (EMG) activity in four muscles was recorded and perceived central, local low-back and thigh exertion were assessed during the lifting modes. No significant difference was found in power output between the two lifting techniques. Despite this the mean O2 consumption was significantly greater during maximal squat lifting [38.7 (SD 5.8) ml.kg-1.min-1] than maximal stoop lifting [32.9 (SD 5.7) ml.kg-1.min-1] (P squat lifting correlated highly with that of maximal treadmill running (r = 0.928, P squat lifting than during stoop lifting. The EMG recordings showed a higher activity for the vastus lateralis muscle and lower activity for the biceps femoris muscle during squat lifting than during stoop lifting. Related to the maximal voluntary contraction, the erector spinae muscle showed the highest activity irrespective of lifting technique.

  6. Estimation of maximal oxygen uptake without exercise testing in Korean healthy adult workers.

    Science.gov (United States)

    Jang, Tae-Won; Park, Shin-Goo; Kim, Hyoung-Ryoul; Kim, Jung-Man; Hong, Young-Seoub; Kim, Byoung-Gwon

    2012-08-01

    Maximal oxygen uptake is generally accepted as the most valid and reliable index of cardiorespiratory fitness and functional aerobic capacity. The exercise test for measuring maximal oxygen uptake is unsuitable for screening tests in public heath examinations, because of the potential risks of exercise exertion and time demands. We designed this study to determine whether work-related physical activity is a potential predictor of maximal oxygen uptake, and to develop a maximal oxygen uptake equation using a non-exercise regression model for the cardiorespiratory fitness test in Korean adult workers. Study subjects were adult workers of small-sized companies in Korea. Subjects with history of disease such as hypertension, diabetes, asthma and angina were excluded. In total, 217 adult subjects (113 men of 21-55 years old and 104 women of 20-64 years old) were included. Self-report questionnaire survey was conducted on study subjects, and maximal oxygen uptake of each subject was measured with the exercise test. The statistical analysis was carried out to develop an equation for estimating maximal oxygen uptake. The predictors for estimating maximal oxygen uptake included age, gender, body mass index, smoking, leisure-time physical activity and the factors representing work-related physical activity. The work-related physical activity was identified to be a predictor of maximal oxygen uptake. Moreover, the equation showed high validity according to the statistical analysis. The equation for estimating maximal oxygen uptake developed in the present study could be used as a screening test for assessing cardiorespiratory fitness in Korean adult workers.

  7. Maximal violation of Bell's inequalities for algebras of observables in tangent spacetime regions

    International Nuclear Information System (INIS)

    Summers, S.J.; Werner, R.

    1988-01-01

    We continue our study of Bell's inequalities and quantum field theory. It is shown in considerably broader generality than in our previous work that algebras of local observables corresponding to complementary wedge regions maximally violate Bell's inequality in all normal states. Pairs of commuting von Neumann algebras that maximally violate Bell's inequalities in all normal states are characterized. Algebras of local observables corresponding to tangent double cones are shown to maximally violate Bell's inequalities in all normal states in dilatation-invariant theories, in free quantum field models, and in a class of interacting models. Further, it is proven that such algebras are not split in any theory with an ultraviolet scaling limit

  8. Factors associated with maximal walking speed among older community-living adults

    DEFF Research Database (Denmark)

    Sallinen, Janne; Mänty, Minna; Leinonen, Raija

    2011-01-01

    07330512) involving 605 community-living ambulatory adults aged 75-81 years. Maximal walking speed, leg extensor power, standing balance and body mass index were measured at the research center. Physical activity, smoking, use of alcohol, chronic diseases and depressive symptoms were self-reported using...... standard questionnaires. Results: The mean maximal walking speed was 1.4 m/s (range 0.3-2.9). In linear regression analysis, age, gender and body mass index explained 11% of the variation in maximal walking speed. Adding leg extensor power and standing balance into the model increased the variation...

  9. Outer measures and weak type estimates of Hardy-Littlewood maximal operators

    Directory of Open Access Journals (Sweden)

    Terasawa Yutaka

    2006-01-01

    Full Text Available We will introduce the times modified centered and uncentered Hardy-Littlewood maximal operators on nonhomogeneous spaces for . We will prove that the times modified centered Hardy-Littlewood maximal operator is weak type bounded with constant when if the Radon measure of the space has "continuity" in some sense. In the proof, we will use the outer measure associated with the Radon measure. We will also prove other results of Hardy-Littlewood maximal operators on homogeneous spaces and on the real line by using outer measures.

  10. Recurrent glioblastomas in the elderly after maximal first-line treatment: does preserved overall condition warrant a maximal second-line treatment?

    Science.gov (United States)

    Zanello, Marc; Roux, Alexandre; Ursu, Renata; Peeters, Sophie; Bauchet, Luc; Noel, Georges; Guyotat, Jacques; Le Reste, Pierre-Jean; Faillot, Thierry; Litre, Fabien; Desse, Nicolas; Emery, Evelyne; Petit, Antoine; Peltier, Johann; Voirin, Jimmy; Caire, François; Barat, Jean-Luc; Vignes, Jean-Rodolphe; Menei, Philippe; Langlois, Olivier; Dezamis, Edouard; Carpentier, Antoine; Dam Hieu, Phong; Metellus, Philippe; Pallud, Johan

    2017-11-01

    A growing literature supports maximal safe resection followed by standard combined chemoradiotherapy (i.e. maximal first-line therapy) for selected elderly glioblastoma patients. To assess the prognostic factors from recurrence in elderly glioblastoma patients treated by maximal safe resection followed by standard combined chemoradiotherapy as first-line therapy. Multicentric retrospective analysis comparing the prognosis and optimal oncological management of recurrent glioblastomas between 660 adult patients aged of patients aged of ≥70 years (elderly group) harboring a supratentorial glioblastoma treated by maximal first-line therapy. From recurrence, both groups did not significantly differ regarding Karnofsky performance status (KPS) (p = 0.482). Oncological treatments from recurrence significantly differed: patients of the elderly group received less frequently oncological treatment from recurrence (p oncological treatment from recurrence (p patients had substandard care from recurrence whereas age did not impact overall survival from recurrence contrary to KPS at recurrence <70. Treatment options from recurrence should include repeat surgery, second line chemotherapy and anti-angiogenic agents.

  11. Real-time traffic management to maximize throughput of automated vehicles.

    Science.gov (United States)

    2015-03-01

    In intelligent transportation systems, most of the research work has focused on lane change assistant : systems. No existing work considers minimizing the disruption of traffic flow by maximizing the number : of lane changes while eliminating the col...

  12. Physiological and morphological determinants of maximal expiratory flow in chronic obstructive lung disease

    NARCIS (Netherlands)

    H.A.W.M. Tiddens (Harm); J.M. Bogaard (Jan); J.C. de Jongste (Johan); W.C.J. Hop (Wim); H.O. Coxson (Harvey); P.D. Pare

    1996-01-01

    textabstractMaximal expiratory flow in chronic obstructive pulmonary disease (COPD) could be reduced by three different mechanisms; loss of lung elastic recoil, decreased airway conductance upstream of flow-limiting segments; and increased collapsibility of airways.

  13. Bounds on absolutely maximally entangled states from shadow inequalities, and the quantum MacWilliams identity

    Science.gov (United States)

    Huber, Felix; Eltschka, Christopher; Siewert, Jens; Gühne, Otfried

    2018-04-01

    A pure multipartite quantum state is called absolutely maximally entangled (AME), if all reductions obtained by tracing out at least half of its parties are maximally mixed. Maximal entanglement is then present across every bipartition. The existence of such states is in many cases unclear. With the help of the weight enumerator machinery known from quantum error correction and the shadow inequalities, we obtain new bounds on the existence of AME states in dimensions larger than two. To complete the treatment on the weight enumerator machinery, the quantum MacWilliams identity is derived in the Bloch representation. Finally, we consider AME states whose subsystems have different local dimensions, and present an example for a 2×3×3×3 system that shows maximal entanglement across every bipartition.

  14. Maximization of Sums of Quotients of Quadratic Forms and Some Generalizations.

    Science.gov (United States)

    Kiers, Henk A. L.

    1995-01-01

    Monotonically convergent algorithms are described for maximizing sums of quotients of quadratic forms. Six (constrained) functions are investigated. The general formulation of the functions and the algorithms allow for application of the algorithms in various situations in multivariate analysis. (SLD)

  15. Effects of cluster vs. traditional plyometric training sets on maximal-intensity exercise performance

    Directory of Open Access Journals (Sweden)

    Abbas Asadi

    2016-01-01

    Conclusions: Although both plyometric training methods improved lower body maximal-intensity exercise performance, the traditional sets methods resulted in greater adaptations in sprint performance, while the cluster sets method resulted in greater jump and agility adaptations.

  16. A Local Scalable Distributed Expectation Maximization Algorithm for Large Peer-to-Peer Networks

    Data.gov (United States)

    National Aeronautics and Space Administration — This paper describes a local and distributed expectation maximization algorithm for learning parameters of Gaussian mixture models (GMM) in large peer-to-peer (P2P)...

  17. PERTURBATION ESTIMATES FOR THE MAXIMAL SOLUTION OF A NONLINEAR MATRIX EQUATION

    Directory of Open Access Journals (Sweden)

    Vejdi I. Hasanov

    2017-06-01

    Full Text Available In this paper a nonlinear matrix equation is considered. Perturba- tion estimations for the maximal solution of the considered equation are obtained. The results are illustrated by the use of numerical ex- amples.

  18. Maximal bite force and surface EMG in patients with myasthenia gravis

    NARCIS (Netherlands)

    Weijnen, FG; Wokke, JHJ; Kuks, JBM; van der Glas, HW; Bosman, F

    2000-01-01

    Masticatory muscle strength was quantified in patients with bulbar myasthenia gravis and compared with that of patients with ocular myasthenia gravis, patients in clinical remission (whether or not pharmacological) who previously suffered from bulbar myasthenia gravis, and healthy subjects. Maximal

  19. Effect of ski boot rear stiffness (SBRS) on maximal ACL force during injury prone landing movements in alpine ski racing: A study with a musculoskeletal simulation model.

    Science.gov (United States)

    Eberle, Robert; Heinrich, Dieter; Kaps, Peter; Oberguggenberger, Michael; Nachbauer, Werner

    2017-06-01

    A common anterior cruciate ligament (ACL) injury situation in alpine ski racing is landing back-weighted after a jump. Simulated back-weighted landing situations showed higher ACL-injury risk for increasing ski boot rear stiffness (SBRS) without considering muscles. It is well known that muscle forces affect ACL tensile forces during landing. The purpose of this study is to investigate the effect of different SBRS on the maximal ACL tensile forces during injury prone landings considering muscle forces by a two-dimensional musculoskeletal simulation model. Injury prone situations for ACL-injuries were generated by the musculoskeletal simulation model using measured kinematics of a non-injury situation and the method of Monte Carlo simulation. Subsequently, the SBRS was varied for injury prone landings. The maximal ACL tensile forces and contributing factors to the ACL forces were compared for the different SBRS. In the injury prone landings the maximal ACL tensile forces increased with increasing SBRS. It was found that the higher maximal ACL force was caused by higher forces acting on the tibia by the boot and by higher quadriceps muscle forces both due to the higher SBRS. Practical experience suggested that the reduction of SBRS is not accepted by ski racers due to performance reasons. Thus, preventive measures may concentrate on the reduction of the quadriceps muscle force during impact.

  20. Incentive Compatible Influence Maximization in Social Networks and Application to Viral Marketing

    OpenAIRE

    Mohite, Mayur; Narahari, Y.

    2011-01-01

    Information diffusion and influence maximization are important and extensively studied problems in social networks. Various models and algorithms have been proposed in the literature in the context of the influence maximization problem. A crucial assumption in all these studies is that the influence probabilities are known to the social planner. This assumption is unrealistic since the influence probabilities are usually private information of the individual agents and strategic agents may no...

  1. A maximal element theorem in FWC-spaces and its applications.

    Science.gov (United States)

    Lu, Haishu; Hu, Qingwen; Miao, Yulin

    2014-01-01

    A maximal element theorem is proved in finite weakly convex spaces (FWC-spaces, in short) which have no linear, convex, and topological structure. Using the maximal element theorem, we develop new existence theorems of solutions to variational relation problem, generalized equilibrium problem, equilibrium problem with lower and upper bounds, and minimax problem in FWC-spaces. The results represented in this paper unify and extend some known results in the literature.

  2. The properties and interrelationships of various force-time parameters during maximal repeated rhythmic grip.

    Science.gov (United States)

    Nakada, Masakatsu; Demura, Shinichi; Yamaji, Shunsuke

    2007-01-01

    The purpose of this study was to examine the properties and interrelationships of various force-time parameters including the inflection point for the rate of decline in force during a maximal repeated rhythmic grip. Fifteen healthy males (age M=21.5, SD=2.1 yr, height M=172.4, SD=5.7 cm, body mass M=68.2, SD=9.2 kg) participated in this study. Subjects performed a maximal repeated rhythmic grip with maximal effort with a target frequency of 30 grip.min(-1) for 6 min. The force value decreased linearly and markedly until about 70% of maximal strength for about 55 s after the onset of a maximal repeated rhythmic grip, and then decreased moderately. Because all parameters showed fair or good correlations between 3 min and 6 min, they are considered to be able to sufficiently evaluate muscle endurance for 3 min instead of 6 min. However, there were significant differences between 3 min and 6 min in the integrated area, the final force, the rate of the decrement constant (k) fitting the force decreasing data to y=ae(-kx)+b and the force of maximal difference between the force and a straight line from peak force to the final force. Their parameters may vary generally by the length of a steady state, namely, a measurement time. The final force value before finishing and the rate of the decrement constant (k) reflect the latter phase during a maximal repeated rhythmic grip. Although many parameters show relatively high mutual relationships, the rate constant (k) shows relatively low correlations with other parameters. We inferred that decreasing the time until 80% of maximal strength and the amount of the decrement force for the first 1 min reflect a linear decrease in the initial phase.

  3. Relations of morphological characteristics and maximal oxygen consumption of fourth grade pupils based on gender

    Directory of Open Access Journals (Sweden)

    Jakovljević Vladimir

    2014-01-01

    Full Text Available On a sample of 71 respondents, 37 boys and 34 girls, age of fourth grade elementary school, accordingly 9 years +/- 6 months, it is assessed correlation and prediction of maximal oxygen consumption based measures of morphological range. Maximum oxygen consumption was measured by indirect method, using a field test of maximal multiple load of feedback running at 20 meters. Range of morphology was analyzed based on 5 measures of longitudinal dimensionality, 4 measures of volume and body mass and 3 measures of transversal dimensionality. Results of correlation analysis showed that in both sexes there was no statistically significant correlation between results of maximal oxygen consumption and measures of longitudinal dimensionality, while regression analysis confirmed that there was no statistically significant prediction of maximum oxygen consumption based on measures of longitudinal dimensionality. While the correlation analysis deduced that part of volume measures and body mass and transversal dimensionality have statistically significant correlation only with female respondents with results of maximal oxygen consumption. Regression analysis showed statistically significant prediction of maximal oxygen consumption based on part of volume measures and body mass and transversal dimensionality. It is determined that female respondents with larger volumes of the thigh and lower leg, accordingly with smaller diameters of knee joint and ankle joint most likely will achieve better results in applied test, and therefore higher maximal oxygen consumption.

  4. Optimal Energy Management for a Smart Grid using Resource-Aware Utility Maximization

    Science.gov (United States)

    Abegaz, Brook W.; Mahajan, Satish M.; Negeri, Ebisa O.

    2016-06-01

    Heterogeneous energy prosumers are aggregated to form a smart grid based energy community managed by a central controller which could maximize their collective energy resource utilization. Using the central controller and distributed energy management systems, various mechanisms that harness the power profile of the energy community are developed for optimal, multi-objective energy management. The proposed mechanisms include resource-aware, multi-variable energy utility maximization objectives, namely: (1) maximizing the net green energy utilization, (2) maximizing the prosumers' level of comfortable, high quality power usage, and (3) maximizing the economic dispatch of energy storage units that minimize the net energy cost of the energy community. Moreover, an optimal energy management solution that combines the three objectives has been implemented by developing novel techniques of optimally flexible (un)certainty projection and appliance based pricing decomposition in an IBM ILOG CPLEX studio. A real-world, per-minute data from an energy community consisting of forty prosumers in Amsterdam, Netherlands is used. Results show that each of the proposed mechanisms yields significant increases in the aggregate energy resource utilization and welfare of prosumers as compared to traditional peak-power reduction methods. Furthermore, the multi-objective, resource-aware utility maximization approach leads to an optimal energy equilibrium and provides a sustainable energy management solution as verified by the Lagrangian method. The proposed resource-aware mechanisms could directly benefit emerging energy communities in the world to attain their energy resource utilization targets.

  5. Maximal hypersurfaces and foliations of constant mean curvature in general relativity

    International Nuclear Information System (INIS)

    Marsden, J.E.; Tipler, F.J.; Texas Univ., Austin

    1980-01-01

    We prove theorems on existence, uniqueness and smoothness of maximal and constant mean curvature compact spacelike hypersurfaces in globally hyperbolic spacetimes. The uniqueness theorem for maximal hypersurfaces of Brill and Flaherty, which assumed matter everywhere, is extended to specetimes that are vacuum and non-flat or that satisfy a generic-type condition. In this connection we show that under general hypotheses, a spatially closed universe with a maximal hypersurface must be Wheeler universe; i.e. be closed in time as well. The existence of Lipschitz achronal maximal volume hypersurfaces under the hypothesis that candidate hypersurfaces are bounded away from the singularity is proved. This hypothesis is shown to be valid in two cases of interest: when the singularities are of strong curvature type, and when the singularity is a single ideal point. Some properties of these maximal volume hypersurfaces and difficulties with Avez' original arguments are discussed. The difficulties involve the possibility that the maximal volume hypersurface can be null on certain portions; we present an incomplete argument which suggests that these hypersurfaces are always smooth, but prove that an a priori bound on the second fundamental form does imply smoothness. An extension of the perturbation theorem of Choquet-Bruhat, Fischer and Marsden is given and conditions under which local foliantions by constant mean curvature hypersurfaces can be extended to global ones is obtained. (orig.)

  6. Effect of angular velocity on soleus and medial gastrocnemius H-reflex during maximal concentric and eccentric muscle contraction.

    Science.gov (United States)

    Duclay, Julien; Robbe, Alice; Pousson, Michel; Martin, Alain

    2009-10-01

    At rest, the H-reflex is lower during lengthening than shortening actions. During passive lengthening, both soleus (SOL) and medial gastrocnemius (MG) H-reflex amplitudes decrease with increasing angular velocity. This study was designed to investigate whether H-reflex amplitude is affected by angular velocity during concentric and eccentric maximal voluntary contraction (MVC). Experiments were performed on nine healthy men. At a constant angular velocity of 60 degrees /s and 20 degrees /s, maximal H-reflex and M-wave potentials were evoked at rest (i.e., H(max) and M(max), respectively) and during concentric and eccentric MVC (i.e., H(sup) and M(sup), respectively). Regardless of the muscle, H(max)/M(max) was lower during lengthening than shortening actions and the H(sup)/M(sup) ratio was higher than H(max)/M(max) during lengthening actions. Whereas no action type and angular velocity effects on the MG H(sup)/M(sup) were found, the SOL H(sup)/M(sup) was lower during eccentric than concentric MVC and this depression was increased with higher angular velocity. Our findings indicate that the depression of the H-reflex amplitude during eccentric compared to concentric MVC depends mainly on the amount of inhibition induced by lengthening action. In conclusion, H-reflex should be evoked during both passive and active dynamic trials to evaluate the plasticity of the spinal loop.

  7. Maximize the operating profit of a SWRO-PRO integrated process for optimal water production and energy recovery

    KAUST Repository

    Wan, Chun Feng

    2016-03-28

    Pressure retarded osmosis (PRO) is a promising technology to reduce the specific energy consumption and the operating expenditure of a seawater reverse osmosis (SWRO) plant. In this study, a simple analytical PRO model is developed to predict the PRO performance as the dilution of draw solutions occurs. The model can predict the PRO performance with a high accuracy without carrying out complicated integrations and experiments. The operating profit of SWRO-PRO is also studied by calculating the profit generated for every m3 of seawater entering the process because maximizing the operating profit is the uttermost objective of the SWRO-PRO process. Based on the PRO analytical model, the operating profit and the dynamics of the SWRO-PRO process, a strategy has been proposed to maximize the operating profit of the SWRO-PRO process while maintaining the highest power density of the PRO membranes. This study proves that integration of SWRO with PRO can (1) push the SWRO to a higher recovery and maintain its high profitability, (2) effectively reduce the specific energy consumption of desalination by up to 35% and (3) increase the operating profit up to 100%. © 2016 Elsevier Ltd.

  8. Acute static vibration-induced stretching enhanced muscle viscoelasticity but did not affect maximal voluntary contractions in footballers.

    Science.gov (United States)

    Jemni, Monèm; Mkaouer, Bessem; Marina, Michel; Asllani, Arben; Sands, William A

    2014-11-01

    The aim of this study was to compare the effects of acute vibration-enhanced static stretching and/or static stretching alone on the strength and flexibility of the hamstrings and quadriceps muscles. Twenty-one male footballers participated in this study (21.9 ± 1.8 years; 75.54 ± 7.3 kg; 178.7 ± 6.5 cm). The experiment started with 5 minutes standardized warm-up followed by (a) baseline flexibility pretest (Split Test); (b) maximal voluntary flexion and extension (isokinetic strength) of the knee; (c) Treatment or Sham involving 45-second stretch with or without vibration for the hamstring and quadriceps muscle groups with 10-second rest between; and (d) posttest repeating the measures of the pretest. Each player randomly performed both trials on separate occasions. The vibration device operated at 35 Hz with 2 mm amplitude. Stretching with vibration statistically increased hamstring flexibility by 7.8% (p ≤ 0.05) when compared with stretching without vibration. No statistical differences for hamstring or quadriceps strength were noted between treatment conditions. There was no statistical correlation between flexibility and strength measurements. In conclusion, flexibility increased with vibration-enhanced static stretching; however, no change was evident in the maximal voluntary contractions of the knee flexors and extensors.

  9. Application of an expectation maximization method to the reconstruction of X-ray-tube spectra from transmission data

    Energy Technology Data Exchange (ETDEWEB)

    Endrizzi, M., E-mail: m.endrizzi@ucl.ac.uk [Dipartimento di Fisica, Università di Siena, Via Roma 56, 53100 Siena (Italy); Istituto Nazionale di Fisica Nucleare, Sezione di Pisa, Largo B. Pontecorvo 3, 56127 Pisa (Italy); Delogu, P. [Istituto Nazionale di Fisica Nucleare, Sezione di Pisa, Largo B. Pontecorvo 3, 56127 Pisa (Italy); Dipartimento di Fisica “E. Fermi”, Università di Pisa, Largo B. Pontecorvo 3, 56127 Pisa (Italy); Oliva, P. [Dipartimento di Chimica e Farmacia, Università di Sassari, via Vienna 2, 07100 Sassari (Italy); Istituto Nazionale di Fisica Nucleare, Sezione di Cagliari, s.p. per Monserrato-Sestu Km 0.700, 09042 Monserrato (Italy)

    2014-12-01

    An expectation maximization method is applied to the reconstruction of X-ray tube spectra from transmission measurements in the energy range 7–40 keV. A semiconductor single-photon counting detector, ionization chambers and a scintillator-based detector are used for the experimental measurement of the transmission. The number of iterations required to reach an approximate solution is estimated on the basis of the measurement error, according to the discrepancy principle. The effectiveness of the stopping rule is studied on simulated data and validated with experiments. The quality of the reconstruction depends on the information available on the source itself and the possibility to add this knowledge to the solution process is investigated. The method can produce good approximations provided that the amount of noise in the data can be estimated. - Highlights: • An expectation maximization method was used together with the discrepancy principle. • The discrepancy principle is a suitable criterion for stopping the iteration. • The method can be applied to a variety of detectors/experimental conditions. • The minimum information required is the amount of noise that affects the data. • Improved results are achieved by inserting more information when available.

  10. Closed-form expressions for flip angle variation that maximize total signal in T1-weighted rapid gradient echo MRI.

    Science.gov (United States)

    Drobnitzky, Matthias; Klose, Uwe

    2017-03-01

    Magnetization-prepared rapid gradient-echo (MPRAGE) sequences are commonly employed for T1-weighted structural brain imaging. Following a contrast preparation radiofrequency (RF) pulse, the data acquisition proceeds under nonequilibrium conditions of the relaxing longitudinal magnetization. Variation of the flip angle can be used to maximize total available signal. Simulated annealing or greedy algorithms have so far been published to numerically solve this problem, with signal-to-noise ratios optimized for clinical imaging scenarios by adhering to a predefined shape of the signal evolution. We propose an unconstrained optimization of the MPRAGE experiment that employs techniques from resource allocation theory. A new dynamic programming solution is introduced that yields closed-form expressions for optimal flip angle variation. Flip angle series are proposed that maximize total transverse magnetization (Mxy) for a range of physiologic T1 values. A 3D MPRAGE sequence is modified to allow for a controlled variation of the excitation angle. Experiments employing a T1 contrast phantom are performed at 3T. 1D acquisitions without phase encoding permit measurement of the temporal development of Mxy. Image mean signal and standard deviation for reference flip angle trains are compared in 2D measurements. Signal profiles at sharp phantom edges are acquired to access image blurring related to nonuniform Mxy development. A novel closed-form expression for flip angle variation is found that constitutes the optimal policy to reach maximum total signal. It numerically equals previously published results of other authors when evaluated under their simplifying assumptions. Longitudinal magnetization (Mz) is exhaustively used without causing abrupt changes in the measured MR signal, which is a prerequisite for artifact free images. Phantom experiments at 3T verify the expected benefit for total accumulated k-space signal when compared with published flip angle series. Describing

  11. Maximal strength, number of repetitions, and total volume are differently affected by static-, ballistic-, and proprioceptive neuromuscular facilitation stretching.

    Science.gov (United States)

    Barroso, Renato; Tricoli, Valmor; Santos Gil, Saulo Dos; Ugrinowitsch, Carlos; Roschel, Hamilton

    2012-09-01

    Stretching exercises have been traditionally incorporated into warm-up routines before training sessions and sport events. However, the effects of stretching on maximal strength and strength endurance performance seem to depend on the type of stretching employed. The objective of this study was to compare the effects of static stretching (SS), ballistic stretching (BS), and proprioceptive neuromuscular facilitation (PNF) stretching on maximal strength, number of repetitions at a submaximal load, and total volume (i.e., number of repetitions × external load) in a multiple-set resistance training bout. Twelve strength-trained men (20.4 ± 4.5 years, 67.9 ± 6.3 kg, 173.3 ± 8.5 cm) volunteered to participate in this study. All of the subjects completed 8 experimental sessions. Four experimental sessions were designed to test maximal strength in the leg press (i.e., 1 repetition maximum [1RM]) after each stretching condition (SS, BS, PNF, or no-stretching [NS]). During the other 4 sessions, the number of repetitions performed at 80% 1RM was assessed after each stretching condition. All of the stretching protocols significantly improved the range of motion in the sit-and-reach test when compared with NS. Further, PNF induced greater changes in the sit-and-reach test than BS did (4.7 ± 1.6, 2.9 ± 1.5, and 1.9 ± 1.4 cm for PNF, SS, and BS, respectively). Leg press 1RM values were decreased only after the PNF condition (5.5%, p < 0.001). All the stretching protocols significantly reduced the number of repetitions (SS: 20.8%, p < 0.001; BS: 17.8%, p = 0.01; PNF: 22.7%, p < 0.001) and total volume (SS: 20.4%, p < 0.001; BS: 17.9%, p = 0.01; PNF: 22.4%, p < 0.001) when compared with NS. The results from this study suggest that, to avoid a decrease in both the number of repetitions and total volume, stretching exercises should not be performed before a resistance training session. Additionally, strength-trained individuals may experience reduced maximal dynamic strength

  12. Auditory Time-Frequency Masking for Spectrally and Temporally Maximally-Compact Stimuli.

    Science.gov (United States)

    Necciari, Thibaud; Laback, Bernhard; Savel, Sophie; Ystad, Sølvi; Balazs, Peter; Meunier, Sabine; Kronland-Martinet, Richard

    2016-01-01

    Many audio applications perform perception-based time-frequency (TF) analysis by decomposing sounds into a set of functions with good TF localization (i.e. with a small essential support in the TF domain) using TF transforms and applying psychoacoustic models of auditory masking to the transform coefficients. To accurately predict masking interactions between coefficients, the TF properties of the model should match those of the transform. This involves having masking data for stimuli with good TF localization. However, little is known about TF masking for mathematically well-localized signals. Most existing masking studies used stimuli that are broad in time and/or frequency and few studies involved TF conditions. Consequently, the present study had two goals. The first was to collect TF masking data for well-localized stimuli in humans. Masker and target were 10-ms Gaussian-shaped sinusoids with a bandwidth of approximately one critical band. The overall pattern of results is qualitatively similar to existing data for long maskers. To facilitate implementation in audio processing algorithms, a dataset provides the measured TF masking function. The second goal was to assess the potential effect of auditory efferents on TF masking using a modeling approach. The temporal window model of masking was used to predict present and existing data in two configurations: (1) with standard model parameters (i.e. without efferents), (2) with cochlear gain reduction to simulate the activation of efferents. The ability of the model to predict the present data was quite good with the standard configuration but highly degraded with gain reduction. Conversely, the ability of the model to predict existing data for long maskers was better with than without gain reduction. Overall, the model predictions suggest that TF masking can be affected by efferent (or other) effects that reduce cochlear gain. Such effects were avoided in the experiment of this study by using maximally

  13. Auditory Time-Frequency Masking for Spectrally and Temporally Maximally-Compact Stimuli.

    Directory of Open Access Journals (Sweden)

    Thibaud Necciari

    Full Text Available Many audio applications perform perception-based time-frequency (TF analysis by decomposing sounds into a set of functions with good TF localization (i.e. with a small essential support in the TF domain using TF transforms and applying psychoacoustic models of auditory masking to the transform coefficients. To accurately predict masking interactions between coefficients, the TF properties of the model should match those of the transform. This involves having masking data for stimuli with good TF localization. However, little is known about TF masking for mathematically well-localized signals. Most existing masking studies used stimuli that are broad in time and/or frequency and few studies involved TF conditions. Consequently, the present study had two goals. The first was to collect TF masking data for well-localized stimuli in humans. Masker and target were 10-ms Gaussian-shaped sinusoids with a bandwidth of approximately one critical band. The overall pattern of results is qualitatively similar to existing data for long maskers. To facilitate implementation in audio processing algorithms, a dataset provides the measured TF masking function. The second goal was to assess the potential effect of auditory efferents on TF masking using a modeling approach. The temporal window model of masking was used to predict present and existing data in two configurations: (1 with standard model parameters (i.e. without efferents, (2 with cochlear gain reduction to simulate the activation of efferents. The ability of the model to predict the present data was quite good with the standard configuration but highly degraded with gain reduction. Conversely, the ability of the model to predict existing data for long maskers was better with than without gain reduction. Overall, the model predictions suggest that TF masking can be affected by efferent (or other effects that reduce cochlear gain. Such effects were avoided in the experiment of this study by using

  14. Maximizing effectiveness of adaptation action in Pacific Island communities using coastal wave attenuation models

    Science.gov (United States)

    Jung, H.; Carruthers, T.; Allison, M. A.; Weathers, D.; Moss, L.; Timmermans, H.

    2017-12-01

    Pacific Island communities are highly vulnerable to the effects of climate change, specifically accelerating rates of sea level rise, changes to storm intensity and associated rainfall patterns resulting in flooding and shoreline erosion. Nature-based adaptation is being planned not only to reduce the risk from shoreline erosion, but also to support benefits of a healthy ecosystem (e.g., supporting fisheries or coral reefs). In order to assess potential effectiveness of the nature-based actions to dissipate wave energy, two-dimensional X-Beach models were developed to predict the wave attenuation effect of coastal adaptation actions at the pilot sites—the villages of Naselesele and Somosomo on Taveuni island, Fiji. Both sites are experiencing serious shoreline erosion due to sea level rise and storm wave. The water depth (single-beam bathymetry), land elevation (truck-based LiDAR), and vegetation data including stem density and height were collected in both locations in a June 2017 field experiment. Wave height and water velocity were also measured for the model setup and calibration using a series of bottom-mounted instruments deployed in the 0-15 m water depth portions of the study grid. The calibrated model will be used to evaluate a range of possible adaptation actions identified by the community members of Naselesele and Somosomo. Particularly, multiple storm scenario runs with management-relevant shoreline restoration/adaptation options will be implemented to evaluate efficiencies of each adaptation action (e.g., no action, with additional planted trees, with sand mining, with seawalls constructed with natural materials, etc.). These model results will help to better understand how proposed adaption actions may influence future shoreline change and maximize benefits to communities in island nations across the SW Pacific.

  15. Ideal vegetation height maximizes sedimentation in freshwater deltaic marshes during flood

    Science.gov (United States)

    Nardin, W.; Edmonds, D. A.

    2013-12-01

    River deltas are complex environments affected by the morphodynamic interaction between flow and sediment transport. This morphodynamic interaction is potentially affected by the freshwater marsh vegetation (e.g. sagittaria and typha) on the exposed surfaces of emergent deltaic islands. As a first step, we present modeling results and remote sensing data on how vegetation affects sedimentation within deltaic islands. Our modeling starts from a pre-formed river delta configuration and then we populate it with different vegetation with different height characteristics. We then subject the delta to floods of varying magnitudes to evaluate how vegetation affects sedimentation during a flood. In our numerical experiments vegetation height affects sedimentation in two key ways. Increase in vegetation height causes a non-linear decrease in sediment flux on to the islands (up to 80% when compared to the case without vegetation). On the other hand vegetation slows water velocity and lengthens the residence time of a water particle up to 50%. Even though vegetation reduces the sediment flux onto the islands, the increase in residence time traps more sediment resulting in higher island sedimentation rates when vegetation is present. Interestingly, we find that an intermediate vegetation height that maximizes island sedimentation rate. This occurs because sediment flux exiting the islands decreases faster (due to increase in residence time) than the sediment flux entering the islands. Finally we analyzed the spatial and seasonal evolution of the vegetation on Wax lake delta, Louisiana through the normalized difference vegetation index (NDVI). We find that NDVI varies seasonally as vegetation grows and dies, suggesting that the timing of the arrival flood wave relative to vegetation height is a critical parameter that for predicting sedimentation of deltaic islands.

  16. Reward maximization justifies the transition from sensory selection at childhood to sensory integration at adulthood.

    Science.gov (United States)

    Daee, Pedram; Mirian, Maryam S; Ahmadabadi, Majid Nili

    2014-01-01

    In a multisensory task, human adults integrate information from different sensory modalities--behaviorally in an optimal Bayesian fashion--while children mostly rely on a single sensor modality for decision making. The reason behind this change of behavior over age and the process behind learning the required statistics for optimal integration are still unclear and have not been justified by the conventional Bayesian modeling. We propose an interactive multisensory learning framework without making any prior assumptions about the sensory models. In this framework, learning in every modality and in their joint space is done in parallel using a single-step reinforcement learning method. A simple statistical test on confidence intervals on the mean of reward distributions is used to select the most informative source of information among the individual modalities and the joint space. Analyses of the method and the simulation results on a multimodal localization task show that the learning system autonomously starts with sensory selection and gradually switches to sensory integration. This is because, relying more on modalities--i.e. selection--at early learning steps (childhood) is more rewarding than favoring decisions learned in the joint space since, smaller state-space in modalities results in faster learning in every individual modality. In contrast, after gaining sufficient experiences (adulthood), the quality of learning in the joint space matures while learning in modalities suffers from insufficient accuracy due to perceptual aliasing. It results in tighter confidence interval for the joint space and consequently causes a smooth shift from selection to integration. It suggests that sensory selection and integration are emergent behavior and both are outputs of a single reward maximization process; i.e. the transition is not a preprogrammed phenomenon.

  17. Physiological, Biomechanical, and Maximal Performance Comparisons of Female Soldiers Carrying Loads Using Prototype U.S. Marine Corps Modular Lightweight Load-Carrying Equipment (MOLLE) with Interceptor Body Armor and U.S. Army All-Purpose Lightweight Individual Carrying Equipment (ALICE) with PASGT Body Armor

    National Research Council Canada - National Science Library

    Harman, Everett

    1999-01-01

    The experiment evaluated the physiological, biomechanical, and maximal performance responses of 12 female soldiers carrying loads with prototype Modular Lightweight Load-Carrying Equipment with Interceptor body armor (MOLLE...

  18. Expectation-Maximization-Maximization: A Feasible MLE Algorithm for the Three-Parameter Logistic Model Based on a Mixture Modeling Reformulation.

    Science.gov (United States)

    Zheng, Chanjin; Meng, Xiangbin; Guo, Shaoyang; Liu, Zhengguang

    2017-01-01

    Stable maximum likelihood estimation (MLE) of item parameters in 3PLM with a modest sample size remains a challenge. The current study presents a mixture-modeling approach to 3PLM based on which a feasible Expectation-Maximization-Maximization (EMM) MLE algorithm is proposed. The simulation study indicates that EMM is comparable to the Bayesian EM in terms of bias and RMSE. EMM also produces smaller standard errors (SEs) than MMLE/EM. In order to further demonstrate the feasibility, the method has also been applied to two real-world data sets. The point estimates in EMM are close to those from the commercial programs, BILOG-MG and flexMIRT, but the SEs are smaller.

  19. Expectation-Maximization-Maximization: A Feasible MLE Algorithm for the Three-Parameter Logistic Model Based on a Mixture Modeling Reformulation

    Directory of Open Access Journals (Sweden)

    Chanjin Zheng

    2018-01-01

    Full Text Available Stable maximum likelihood estimation (MLE of item parameters in 3PLM with a modest sample size remains a challenge. The current study presents a mixture-modeling approach to 3PLM based on which a feasible Expectation-Maximization-Maximization (EMM MLE algorithm is proposed. The simulation study indicates that EMM is comparable to the Bayesian EM in terms of bias and RMSE. EMM also produces smaller standard errors (SEs than MMLE/EM. In order to further demonstrate the feasibility, the method has also been applied to two real-world data sets. The point estimates in EMM are close to those from the commercial programs, BILOG-MG and flexMIRT, but the SEs are smaller.

  20. Resistance training for explosive and maximal strength: effects on early and late rate of force development.

    Science.gov (United States)

    Oliveira, Felipe B D; Oliveira, Anderson S C; Rizatto, Guilherme F; Denadai, Benedito S

    2013-01-01

    The aim of the present study was to verify whether strength training designed to improve explosive and maximal strength would influence rate of force development (RFD). Nine men participated in a 6-week knee extensors resistance training program and 9 matched subjects participated as controls. Throughout the training sessions, subjects were instructed to perform isometric knee extension as fast and forcefully as possible, achieving at least 90% maximal voluntary contraction as quickly as possible, hold it for 5 s, and relax. Fifteen seconds separated each repetition (6-10), and 2 min separated each set (3). Pre- and post-training measurements were maximal isometric knee extensor (MVC), RFD, and RFD relative to MVC (i.e., %MVC·s(-1)) in different time-epochs varying from 10 to 250 ms from the contraction onset. The MVC (Nm) increased by 19% (275.8 ± 64.9 vs. 329.8 ± 60.4, p resistance training for explosive and maximal strength. This time-specific RFD adaptation highlight that resistance training programs should consider the specific neuromuscular demands of each sport. Key PointsThe time-specific RFD adaptation evoked by resistance training highlight that the method of analyzing RFD is essential for the interpretation of results.Confirming previous data, maximal contractile RFD and maximal force can be differently influenced by resistance training. Thus, the resistance training programs should consider the specific neuromuscular demands of each sport.In active non-strength trained individuals, a short-term resistance training program designed to increase both explosive and maximal strength seems to reduce the adaptive response (i.e. increased RFDMAX) evoked by training with an intended ballistic effort (i.e. high-RFD contraction).