WorldWideScience

Sample records for single true control-effect

  1. Benchmark Evaluation of True Single Molecular Sequencing to Determine Cystic Fibrosis Airway Microbiome Diversity

    Directory of Open Access Journals (Sweden)

    Andrea Hahn

    2018-05-01

    Full Text Available Cystic fibrosis (CF is an autosomal recessive disease associated with recurrent lung infections that can lead to morbidity and mortality. The impact of antibiotics for treatment of acute pulmonary exacerbations on the CF airway microbiome remains unclear with prior studies giving conflicting results and being limited by their use of 16S ribosomal RNA sequencing. Our primary objective was to validate the use of true single molecular sequencing (tSMS and PathoScope in the analysis of the CF airway microbiome. Three control samples were created with differing amounts of Burkholderia cepacia, Pseudomonas aeruginosa, and Prevotella melaninogenica, three common bacteria found in cystic fibrosis lungs. Paired sputa were also obtained from three study participants with CF before and >6 days after initiation of antibiotics. Antibiotic resistant B. cepacia and P. aeruginosa were identified in concurrently obtained respiratory cultures. Direct sequencing was performed using tSMS, and filtered reads were aligned to reference genomes from NCBI using PathoScope and Kraken and unique clade-specific marker genes using MetaPhlAn. A total of 180–518 K of 6–12 million filtered reads were aligned for each sample. Detection of known pathogens in control samples was most successful using PathoScope. In the CF sputa, alpha diversity measures varied based on the alignment method used, but similar trends were found between pre- and post-antibiotic samples. PathoScope outperformed Kraken and MetaPhlAn in our validation study of artificial bacterial community controls and also has advantages over Kraken and MetaPhlAn of being able to determine bacterial strains and the presence of fungal organisms. PathoScope can be confidently used when evaluating metagenomic data to determine CF airway microbiome diversity.

  2. Endovascular Management of True Renal Arterial Aneurysms: Results from a Single Centre

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Raymond, E-mail: chung.raymond.jh@alexandrahealth.com.sg [Khoo Teck Puat Hospital, Department of Radiology (Singapore); Touska, Philip, E-mail: p.touska@doctors.org.uk [St. George’s Hospital NHS Trust, Department of Radiology (United Kingdom); Morgan, Robert; Belli, Anna-Maria [St. George’s Hospital NHS Trust, Department of Interventional Radiology (United Kingdom)

    2016-01-15

    PurposeTo report a single centre’s experience of the endovascular treatment of renal arterial aneurysms, including techniques and outcomes.Materials and MethodsThis is a retrospective analysis of true renal arterial aneurysms (TRAAs) treated using endovascular techniques over a period of 12 years and 10 months. The clinical presentations, aneurysm characteristics, endovascular techniques and outcomes are reported.ResultsThere were nine TRAA cases with a mean aneurysm size of 21.0 mm, located at the main renal arterial bifurcation in all cases. Onyx{sup ®} was used as the embolic agent of choice (88.9 % cases), with concurrent balloon remodelling. The overall primary technical success rate was 100 %. Repeat intervention was carried out in 1 case, secondary to reperfusion >8 years post-initial treatment. Long-term clinical follow-up was available in 55.6 % of cases (mean 29.8 months; range 3.3–90.1 months). Early post-procedural renal function, as measured by serum creatinine, remained within the normal reference range. Renal parenchymal loss post-embolisation was ≤20 % in 77.8 % of cases, as estimated on imaging. Minor complications included non-target embolization of Onyx{sup ®} with no clinical sequelae (n = 1), transient pain requiring only oral analgesia with no prolongation of hospital stay (n = 2). No major complications occurred as a consequence of embolisation.ConclusionEndovascular therapy is an effective and safe primary therapy for TRAA with high success rate and low morbidity, supplanting surgery as primary therapy. Current experience in the use of Onyx{sup ®} in TRAA is primarily limited to individual case reports, and this represents the largest case series of Onyx{sup ®}-treated TRAAs to date.

  3. First TRUE Stage - Transport of solutes in an interpreted single fracture. Proceedings from the 4th international seminar

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-08-01

    . The outcome of the 4th International Aespoe seminar focused on the TRUE-1 experiments can be summarised in the following main points: There is a general consensus that the observed retardation observed in the TRUE-1 experiments requires diffusion into geological material to be an active process. This supported by the -3/2 slope noted in log-log BTCs. Whether this is due to diffusion (and subsequent sorption) in the altered matrix rock, or in possible fault gouge cannot be differentiated with available data; Some researchers claim that the observed enhanced retardation may be explained by diffusion into stagnant water pools, pure surface sorption, or may be due to an underestimation in the flow-wetted surface area. The latter effect may be attributed to a more complex flow path (multi-layered structure) or three-dimensional effects; A clear differentiation between the principal active process can only assessed by resin injection and subsequent excavation and analysis; It was identified that experiments of TRUE type are important for improving the understanding of retention processes. However, this type of experiment will not be part of a site characterisation programme; It was recommended to broaden the data base from the TRUE-1 site before characterising pore space with resin techniques. This includes tracer dilution tests using sinks in other features than Feature A. The seminar was divided into four sessions: 1. Detailed characterisation of transport-related properties (Three contributions separately indexed). 2. Alternative evaluation of TRUE-1 results (Five contributions separately indexed). 3. Related studies (Three contributions separately indexed). 4. Understanding of retention processes in a single fracture (Two contributions separately indexed)

  4. Determination of vitality in myocardial infarction. Comparison of single- and multi-slice MRI techniques with TurboFlash and TrueFISP sequences

    International Nuclear Information System (INIS)

    Huber, A.; Schoenberg, S.O.; Spannagl, B.; Rieber, J.; Klauss, V.; Reiser, M.F.

    2004-01-01

    The aim of the study was to compare the diagnostic accuracy in imaging viability of the myocardium with a multislice inversions recovery 2D single shot TrueFISP sequence and an established inversion recovery TurboFlash sequence. Twelve patients with myocardial infarction were examined at a 1.5 tesla MR system (Sonata, Siemens, Medical Systems) 10 min after application of a single dose multihance (0,1 mmol/kg body weight) with a 2D multislice technique (inversion recovery single shot TrueFISP), that allows to image the entire short axis during one breathhold and a 2D single slice technique (inversion recovery TurboFlash), that requires one breathhold per slice. Signal intensity was determined in normal myocardium, in the infarcted myocardium and in the left ventricle. The contrast/noise ratio of normal and infarcted myocardium was determined. The areas of hyperintense infarction were compared for both sequence techniques. The multislice single shot 2D IR-TrueFisp sequence has a lower contrast/noise ratio than the IR-TurboFlash sequence (mean values 6.9 vs. 12.5) for viable and non viable myocardium. The assessment of the volume of the infarction is possible with excellent correlation of both techniques (r=0.97, p [de

  5. True Detective

    OpenAIRE

    Gajhede, Andreas; Westmark, [No Value; Bantoulidis, Georgios

    2016-01-01

    This paper examines the HBO’s television-series True Detective, a 2014 crime drama, attempting to point out the central elements of detective-fiction, to be found in its narrative. True Detective narrative is a heavy text with a number of references from various well-known, non-adjacent texts within the field of weird fiction, horror fiction and detective fiction. Therefore, the case study of this research will focus on narratological and literary analysis, in order to discover the predominan...

  6. A review of oral food challenges in children presenting to a single tertiary centre with perceived or true food allergies.

    Science.gov (United States)

    Thalayasingam, Meera; Loo, Evelyn Xiu Ling; Tan, Michelle Meiling; Bever, Hugo Van; Shek, Lynette Pei-Chi

    2015-11-01

    The prevalence of perceived food allergies exceeds that of true food allergies. Unnecessary food avoidance may increase parental and patient anxiety, reduce quality of life and increase the risk of nutritional deficiency. An oral food challenge (OFC) can provide an objective measure regarding the presence or absence of food allergies in a child. This study reviews the indications for and outcomes of OFCs performed on children. A retrospective review was performed on all children who underwent OFCs at the Allergy Unit of the National University Hospital, Singapore, over a three-year period. A total of 197 OFCs were performed among 58 patients (34 male, 24 female). Most of the tests were for allergies to tree nuts (n = 107). Among the OFCs, 43.1% were for foods that were avoided and never eaten due to perceived food allergies, 25.9% were for foods that had previously resulted in positive skin prick tests (SPTs) and/or immunoassay results, 16.2% were for foods thought to worsen eczema and 14.7% were for foods thought to have caused a previous reaction. Of all the OFCs, 5% were positive, although adverse reactions were mostly cutaneous. Challenge-positive patients had either positive SPTs (wheal > 3 mm) or raised serum immunoglobulin E levels to specific foods that they reacted to during the challenges. No episodes of anaphylaxis were reported after the challenge. Most of the patients were able to safely introduce the avoided foods into their diets. OFCs provide an objective assessment for suspected food allergies.

  7. The 15N-leucine single-injection method allows for determining endogenous losses and true digestibility of amino acids in cecectomized roosters.

    Directory of Open Access Journals (Sweden)

    Rujiu Hu

    Full Text Available This study was conducted to assess the influence of dietary protein content in poultry when using the 15N-leucine single-injection method to determine endogenous amino acid losses (EAALs in poultry. Forty-eight cecectomized roosters (2.39 ± 0.23 kg were randomly allocated to eight dietary treatments containing protein levels of 0, 3%, 6%, 9%, 12%, 15%, 18% and 21%. Each bird was precisely fed an experimental diet of 25 g/kg of body weight. After feeding, all roosters were subcutaneously injected with a 15N-leucine solution at a dose of 20 mg/kg of body weight. Blood was sampled 23 h after the injection, and excreta samples were continuously collected during the course of the 48-h experiment. The ratio of 15N-enrichment of leucine in crude mucin to free leucine in plasma ranged from 0.664 to 0.763 and remained relatively consistent (P > 0.05 across all treatments. The amino acid (AA profiles of total endogenous AAs, except isoleucine, alanine, aspartic acid, cysteine, proline and serine, were not influenced (P > 0.05 by dietary protein contents. The predominant endogenous AAs in the excreta were glutamic acid, aspartic acid, threonine, serine and proline. The order of the relative proportions of these predominant AAs also remained relatively constant (P > 0.05. The endogenous losses of total AAs determined with the 15N-leucine single-injection method increased curvilinearly with the dietary protein contents. The true digestibility of most AAs and total AAs was independent of their respective dietary protein levels. Collectively, the 15N-leucine single-injection method is appropriate for determining EAALs and the true digestibility of AAs in poultry fed varying levels of protein-containing ingredients.

  8. Measurement of true density

    International Nuclear Information System (INIS)

    Carr-Brion, K.G.; Keen, E.F.

    1982-01-01

    System for determining the true density of a fluent mixture such as a liquid slurry, containing entrained gas, such as air comprises a restriction in pipe through which at least a part of the mixture is passed. Density measuring means such as gamma-ray detectors and source measure the apparent density of the mixture before and after its passage through the restriction. Solid-state pressure measuring devices are arranged to measure the pressure in the mixture before and after its passage through the restriction. Calculating means, such as a programmed microprocessor, determine the true density from these measurements using relationships given in the description. (author)

  9. The True Scholar.

    Science.gov (United States)

    Bellah, Robert N.

    2000-01-01

    This essay argues for ethical inquiry as the essence of true scholarship. Individual sections address: pure reason versus ethics, the current "age of money" in the university, rational choice theory, and the fatal flaw in rational choice theory that all human actions cannot be explained by it. (DB)

  10. Your True Freedom

    Directory of Open Access Journals (Sweden)

    Jena Rausch

    2015-02-01

    Full Text Available Your True Freedom is about my journey teaching inmates the fundamental truths of self worth, self acceptance and self love--through writing, mindfulness meditation and emotional healing. It is a journey that continues to enlighten me and to heal and free the inmates with whom I work.

  11. Systemic True False

    African Journals Online (AJOL)

    Preferred Customer

    ):. (a). (b). (c). (d). Answer: True systemics are (b & c); False Systemics (a & d). For more examples, see (10 and 11). Na2O2. NaCl. Na. HCl heat /excess. (O). 300°C electrolysis. (molten). NaOH. NaCl. Na. HCl. H2O electrolysis. (solution). NaCl.

  12. Calibration of the apparent temperature of silicon single crystals as a function of their true temperature and their thickness as determined by infrared measurements

    International Nuclear Information System (INIS)

    Smither, R.K.; Fernandez, P.B.

    1993-09-01

    Viewing the surface of objects subjected to high heat fluxes with an infrared camera or infrared sensor has proved to be a very effective method for monitoring the magnitude and distribution of surface temperature on the object. This approach has been quite useful in studies of cooling silicon crystals in monochromators subject to high heat loads. The main drawback to this method is that single crystals of silicon are partially transparent to the infrared radiation monitored in most infrared cameras. This means that the infrared radiation emitted from the surface contains a component that comes from the interior of the crystal and that the intensity of the emitted radiation and thus the apparent temperature of the surface of the crystal depends on the thickness of the crystal and the kind of coating on the back (and/or the front) of the crystal. The apparent temperature of the crystal increases as the crystal is made thicker. A series of experiments were performed at Argonne National Laboratory to calibrate the apparent surface temperature of the crystal as measured with an infrared camera as a function of the crystal thickness and the type of coating (if any) on the back side of the crystal. A good reflecting surface on the back side of the crystal increases the apparent temperature of the crystal and simulates the response of a crystal twice the thickness. These measurements make it possible to interpret the infrared signals from cooled silicon crystals used in past high heat load experiments. A number of examples are given for data taken in synchrotron experiments with high intensity x-ray beams

  13. Radionuclide therapy for true polycythemia

    International Nuclear Information System (INIS)

    Afanasieva, N.I.; Grushka, G.V.; Vasiliev, L.Ya.

    2005-01-01

    Full text: True polycythemia (Vaquez' disease) is the disease of the hemopoietic system of an unknown origin accompanied by increase of erythrocyte count in the peripheral blood with absolute and relative increase in the mass of circulating erythrocytes. True polycythemia is treated with bloodletting and myelosuppressing drugs. This treatment is not always effective. A special place among myelo-depressants is occupied by P-32. Its main therapeutic effect is mediated by the participation in the metabolic processes. Besides DNA damage with beta-radiation, P-32 incorporation by DNA followed by decay and transformation to a stable sulphur isotope (S-32) results in the damage of the structure of nucleic acids, which is main mechanism of cellular proliferation inhibition. Therefore, P-32 is considered a powerful myelosuppressive agent. The indication to P-32 administration is true polycythemia, which, in contrast to secondary polycythemia accompanying numerous diseases, requires special cytostatic treatment. The study involved 152 patients with true polycythemia (76 men and 76 women aged 48) treated with P-32. The treatment was administered in case when bloodletting proved to be ineffective and hematocrit level exceeded 75%. P-32 was administered orally in 100 ml of 10% glucose solution on an empty stomach at a dose of 37-111 MBq with a 4-10-day intervals (mean 6 days). The blood count was checked for 12 weeks. If the number of thrombocytes and leukocytes decreased less than by 25% and the level of hematocrit did not normalize, repeated P-32 treatments were performed. In 13 (8.6%) patients, haematocrit parameters became normal after a single P-32 administration, in 15 (9.9%) patients two treatments with P-32 were necessary to normalize the blood count. In 134 (88.1%) cases P-32 treatment was administered more then two times (maximum 10 treatments). Total P-32 activity ranged from 37 to 740 MBq. Of all the patients who were administered P- 32 treatment, hematological

  14. True bursal pigmented villonodular synovitis

    International Nuclear Information System (INIS)

    Abdelwahab, Ibrahim Fikry; Kenan, Samuel; Steiner, German C.; Abdul-Quader, Mohammed

    2002-01-01

    We describe two cases of pigmented villonodular synovitis affecting true bursae. This study was also designed to discuss the term ''pigmented villonodular bursitis'', not confined to true synovial bursae, sometimes creating misunderstanding. (orig.)

  15. True bursal pigmented villonodular synovitis

    Energy Technology Data Exchange (ETDEWEB)

    Abdelwahab, Ibrahim Fikry [Department of Radiology, New York Methodist Hospital, Affiliated with New York Hospital-Cornell Medical Center, Brooklyn, NY (United States); Kenan, Samuel [Department of Orthopedics, New York University Medical Center, NY (United States); Steiner, German C. [Department of Pathology, Hospital for Joint Diseases/Orthopedic Institute, New York, NY (United States); Abdul-Quader, Mohammed [Department of Radiology, New York Presbyterian Hospital, Columbia University, New York, NY (United States)

    2002-06-01

    We describe two cases of pigmented villonodular synovitis affecting true bursae. This study was also designed to discuss the term ''pigmented villonodular bursitis'', not confined to true synovial bursae, sometimes creating misunderstanding. (orig.)

  16. True and common balsams

    Directory of Open Access Journals (Sweden)

    Dayana L. Custódio

    2012-08-01

    Full Text Available Balsams have been used since ancient times, due to their therapeutic and healing properties; in the perfume industry, they are used as fixatives, and in the cosmetics industry and in cookery, they are used as preservatives and aromatizers. They are generally defined as vegetable material with highly aromatic properties that supposedly have the ability to heal diseases, not only of the body, but also of the soul. When viewed according to this concept, many substances can be considered balsams. A more modern concept is based on its chemical composition and origin: a secretion or exudate of plants that contain cinnamic and benzoic acids, and their derivatives, in their composition. The most common naturally-occurring balsams (i.e. true balsams are the Benzoins, Liquid Storaque and the Balsams of Tolu and Peru. Many other aromatic exudates, such as Copaiba Oil and Canada Balsam, are wrongly called balsam. These usually belong to other classes of natural products, such as essential oils, resins and oleoresins. Despite the understanding of some plants, many plants are still called balsams. This article presents a chemical and pharmacological review of the most common balsams.

  17. True Fibroma of Alveolar Mucosa

    Directory of Open Access Journals (Sweden)

    Shankargouda Patil

    2014-01-01

    Full Text Available Benign fibrous overgrowths are often found in the oral cavity, almost always being reactive/irritational in nature. However, benign mesenchymal neoplasms of the fibroblasts are extremely uncommon. Here we report a case of “True Fibroma of Alveolar Mucosa” for its rarity.

  18. True random numbers from amplified quantum vacuum.

    Science.gov (United States)

    Jofre, M; Curty, M; Steinlechner, F; Anzolin, G; Torres, J P; Mitchell, M W; Pruneri, V

    2011-10-10

    Random numbers are essential for applications ranging from secure communications to numerical simulation and quantitative finance. Algorithms can rapidly produce pseudo-random outcomes, series of numbers that mimic most properties of true random numbers while quantum random number generators (QRNGs) exploit intrinsic quantum randomness to produce true random numbers. Single-photon QRNGs are conceptually simple but produce few random bits per detection. In contrast, vacuum fluctuations are a vast resource for QRNGs: they are broad-band and thus can encode many random bits per second. Direct recording of vacuum fluctuations is possible, but requires shot-noise-limited detectors, at the cost of bandwidth. We demonstrate efficient conversion of vacuum fluctuations to true random bits using optical amplification of vacuum and interferometry. Using commercially-available optical components we demonstrate a QRNG at a bit rate of 1.11 Gbps. The proposed scheme has the potential to be extended to 10 Gbps and even up to 100 Gbps by taking advantage of high speed modulation sources and detectors for optical fiber telecommunication devices.

  19. Automated fuel fabrication- a vision comes true

    International Nuclear Information System (INIS)

    Hemantha Rao, G.V.S.; Prakash, M.S.; Setty, C.R.P.; Gupta, U.C.

    1997-01-01

    When New Uranium Fuel Assembly Project at Nuclear Fuel Complex (NFC) begins production, its operator will have equipment provided with intramachine handling systems working automatically by pressing a single button. Additionally simple low cost inter machine handling systems will further help in critical areas. All these inter and intra machine handling systems will result in improved reliability, productivity and quality. The fault diagnostics, mimics and real time data acquisition systems make the plant more operator friendly. The paper deals with the experience starting from layout, selection of product carriers, different handling systems, the latest technology and the integration of which made the vision on automation in fuel fabrication come true. (author)

  20. Dishonest responding or true virtue?

    DEFF Research Database (Denmark)

    Zettler, Ingo; Hilbig, Benjamin E.; Moshagen, Morten

    2015-01-01

    but troubling proposition that high scores in impression management scales actually reflect honesty rather than dishonest responding. In line with findings indicating that respondents answer to personality questionnaires rather accurately in typical low demand situations, we herein suggest that high impression...... management scores indeed reflect true virtues rather than dishonesty under such conditions. We found support for this idea by replicating previous correlations between impression management scores and virtue-related basic personality traits (including honesty-humility), and additionally provided conclusive...

  1. In search of true friendship

    Directory of Open Access Journals (Sweden)

    Luciana Karine de Souza

    2008-01-01

    Full Text Available The present text proposes a discussion on the concept of true friendship. The argument is grounded mostly on Aristotle's Nicomachean Ethics, Owen Flanagan's ethics as human ecology, and on contemporary authors' works about the Greek philosopher's concept of friendship. Given that human beings flourish through 1 exercising capacities, 2 being moral, and 3 having true friendships, difficulties to establish the level of trust required by true friendships turns the search itself (for them morally valid.O presente texto propõe uma discussão sobre o conceito de amizade verdadeira. A argumentação que fundamenta o trabalho baseia-se em grande parte na Ética a Nicômaco de Aristóteles, na ética como ecologia humana de Owen Flanagan, e em autores contemporâneos sobre o conceito de amizade do filósofo grego. Considerando-se que seres humanos encontram a felicidade mediante 1 o exercício de suas capacidades, 2 ser um ente moral, e 3 ter amizades verdadeiras, as dificuldades no estabelecimento do nível de amizade requerido nas amizades verdadeiras torna a busca (por elas, por si só, algo moralmente válido.

  2. Journalism as Justified True Belief

    OpenAIRE

    Lisboa, Sílvia; Benetti, Marcia

    2015-01-01

    If it is important to think of journalism as a form of knowledge, then how does it become knowledge? How does this process work? In order to answer this question, this article proposes a new understanding of journalism as a subject; presenting it as a justified true belief. We think of journalism being based on pillars of truth and justification, conditions necessary in order for Epistemology to grant it the status of knowledge. We address the concept of truth and show how journalistic report...

  3. Synthesis, structure, and spectroscopic and magnetic characterization of [Mn12O12(O2CCH2But)16(MeOH)4]·MeOH, a Mn12 single-molecule magnet with true axial symmetry.

    Science.gov (United States)

    Lampropoulos, Christos; Murugesu, Muralee; Harter, Andrew G; Wernsdofer, Wolfgang; Hill, Stephen; Dalal, Naresh S; Reyes, Arneil P; Kuhns, Philip L; Abboud, Khalil A; Christou, George

    2013-01-07

    The synthesis and properties are reported of a rare example of a Mn(12) single-molecule magnet (SMM) in truly axial symmetry (tetragonal, I4). [Mn(12)O(12)(O(2)CCH(2)Bu(t))(16)(MeOH)(4)]·MeOH (3·MeOH) was synthesized by carboxylate substitution on [Mn(12)O(12)(O(2)CMe)(16)(H(2)O)(4)]·2MeCO(2)H·4H(2)O (1). The complex was found to possess an S = 10 ground state, as is typical for the Mn(12) family, and displayed both frequency-dependent out-of-phase AC susceptibility signals and hysteresis loops in single-crystal magnetization vs DC field sweeps. The loops also exhibited quantum tunneling of magnetization steps at periodic field values. Single-crystal, high-frequency electron paramagnetic resonance spectra on 3·MeOH using frequencies up to 360 GHz revealed perceptibly sharper signals than for 1. Moreover, careful studies as a function of the magnetic field orientation did not reveal any satellite peaks, as observed for 1, suggesting that the crystals of 3 are homogeneous and do not contain multiple Mn(12) environments. In the single-crystal (55)Mn NMR spectrum in zero applied field, three well-resolved peaks were observed, which yielded hyperfine and quadrupole splitting at three distinct sites. However, observation of a slight asymmetry in the Mn(4+) peak was detectable, suggesting a possible decrease in the local symmetry of the Mn(4+) site. Spin-lattice (T(1)) relaxation studies were performed on single crystals of 3·MeOH down to 400 mK in an effort to approach the quantum tunneling regime, and fitting of the data using multiple functions was employed. The present work and other recent studies continue to emphasize that the new generation of truly high-symmetry Mn(12) complexes are better models for thorough investigation of the physical properties of SMMs than their predecessors such as 1.

  4. Journalism as Justified True Belief

    Directory of Open Access Journals (Sweden)

    Sílvia Lisboa

    2015-12-01

    Full Text Available If it is important to think of journalism as a form of knowledge, then how does it become knowledge? How does this process work? In order to answer this question, this article proposes a new understanding of journalism as a subject; presenting it as a justified true belief. We think of journalism being based on pillars of truth and justification, conditions necessary in order for Epistemology to grant it the status of knowledge. We address the concept of truth and show how journalistic reports are justified to the public as well as consider the central role of credibility in this process. We add to the epistemic conception by using concepts of discourse that help to understand how journalism provides evidence through its intentions, its authority and its ability. This evidence acts like a guide for the reader towards forming opinions on journalistic reports and recognizing journalism as a form of knowledge.

  5. True photographs and false memories.

    Science.gov (United States)

    Lindsay, D Stephen; Hagen, Lisa; Read, J Don; Wade, Kimberley A; Garry, Maryanne

    2004-03-01

    Some trauma-memory-oriented psychotherapists advise clients to review old family photo albums to cue suspected "repressed" memories of childhood sexual abuse. Old photos might cue long-forgotten memories, but when combined with other suggestive influences they might also contribute to false memories. We asked 45 undergraduates to work at remembering three school-related childhood events (two true events provided by parents and one pseudoevent). By random assignment, 23 subjects were also given their school classes' group photos from the years of the to-be-recalled events as memory cues. As predicted, the rate of false-memory reports was dramatically higher in the photo condition than in the no-photo condition. Indeed, the rate of false-memory reports in the photo condition was substantially higher than the rate in any previously published study.

  6. Very true operators on MTL-algebras

    Directory of Open Access Journals (Sweden)

    Wang Jun Tao

    2016-01-01

    Full Text Available The main goal of this paper is to investigate very true MTL-algebras and prove the completeness of the very true MTL-logic. In this paper, the concept of very true operators on MTL-algebras is introduced and some related properties are investigated. Also, conditions for an MTL-algebra to be an MV-algebra and a Gödel algebra are given via this operator. Moreover, very true filters on very true MTL-algebras are studied. In particular, subdirectly irreducible very true MTL-algebras are characterized and an analogous of representation theorem for very true MTL-algebras is proved. Then, the left and right stabilizers of very true MTL-algebras are introduced and some related properties are given. As applications of stabilizer of very true MTL-algebras, we produce a basis for a topology on very true MTL-algebras and show that the generated topology by this basis is Baire, connected, locally connected and separable. Finally, the corresponding logic very true MTL-logic is constructed and the soundness and completeness of this logic are proved based on very true MTL-algebras.

  7. True mean rate measuring system

    International Nuclear Information System (INIS)

    Eichenlaub, D.P.

    1980-01-01

    A digital radiation-monitoring system for nuclear power plants uses digital and microprocessor circuitry to enable rapid processing of pulse information from remote radiation monitors. The pulse rates are analyzed to determine whether new pulse-rate information is statisticaly the same as that previously received and to determine the best possible averaging time, which can be changed so that the statistical error remains below a specified level while the system response time remains short. Several data modules each process the pulse-rate information from several remote radiation monitors. Each data module accepts pulse data from each radiation monitor and measures the true average or mean pulse rate of events occurring with a Poisson distribution to determine the radiation level. They then develop digital output signals which indciate the respective radiation levels and which can be transmitted via multiplexer circuits for additional processing and display. The data modules can accept signals from remote control stations or computer stations via the multiplexer circuit to change operating thresholds and alarm levels in their memories. A check module scans the various data modules to determine whether the output signals are valid. It also acts as a redundant data module and will automatically replace an inoperative unit. (DN)

  8. TRUE Block Scale Continuation Project. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Peter; Byegaard, Johan [Geosigma AB (Sweden); Billaux, Daniel [Itasca Consultants SA (France); Cvetkovic, Vladimir [Royal Inst. of Technology, Stockholm (Sweden); Dershowitz, William; Doe, Thomas [Golder Associates Inc. (United States); Hermanson, Jan [Golder Associates AB (Sweden); Poteri, Antti [VTT (Finland); Tullborg, Eva-Lena [Terralogica AB (Sweden); Winberg, Anders [Conterra AB (SE)] (ed.)

    2007-03-15

    The TRUE Block Scale project was carried out during 1996-2002. This project focused on site characterisation and building of hydrostructural and microstructural models, sorbing tracer experiments in single structures and networks of structures over distances ranging between 1 and 100 m and also involved a unified application of various model approaches for modelling the in situ experiments. In 2002, ANDRA, Posiva, JNC and SKB decided to pursue some remaining issues in the so-called TRUE Block Scale Continuation project (TRUE BS2). The specific objectives of BS2 can be summarised as: 'Improve understanding of transport pathways at the block scale, including assessment of effects of geology and geometry, macrostructure and microstructure'. In order to cater to addressing the stated objective a series of hypotheses were formulated which explored the importance of geological information for predicting transport and retention and the possible differences between transport and retention between transport paths dominated by faults and those dominated by non-fault fractures (background fractures). In the process, prospects for carrying out experiments in fracture networks over longer distances (c 20-100 m) were explored. It was identified that experiments with sorbing tracers over these distances were prohibitive because of the time frames involved and the projected low mass recoveries. Instead the experimental locus was shifted to a geological structure previously not investigated by tracer tests in the TRUE Block Scale experiments. The lower immobile zone retention material properties assigned to background fractures compared to those assigned to the fault-type Structure 19 have been verified by means of back-calculations. The evaluated Type 1 flow path (Structure 19, Flow path I) retention material properties, as expressed by {kappa} parameter, are one order of magnitude higher than for the background fracture flow path. This finding is consistent with the

  9. "True" posterior communicating aneurysms: Three cases, three strategies.

    Science.gov (United States)

    Nery, Breno; Araujo, Ricardo; Burjaili, Bruno; Smith, Timothy R; Rodrigues, Jose Carlos; Silva, Marcelo Nery

    2016-01-01

    The authors provide a review of true aneurysms of the posterior communicating artery (PCoA). Three cases admitted in our hospital are presented and discussed as follows. First patient is a 51-year-old female presenting with a Fisher II, Hunt-Hess III (headache and confusion) subarachnoid hemorrhage (SAH) from a ruptured true aneurysm of the right PCoA. She underwent a successful ipsilateral pterional craniotomy for aneurysm clipping and was discharged on postoperative day 4 without neurological deficit. Second patient is a 53-year-old female with a Fisher I, Hunt-Hess III (headache, mild hemiparesis) SAH and multiple aneurisms, one from left ophthalmic carotid artery and one (true) from right PCoA. These lesions were approached and successfully treated by a single pterional craniotomy on the left side. The patient was discharged 4 days after surgery, with complete recovery of muscle strength during follow-up. Third patient is a 69-year-old male with a Fisher III, Hunt-Hess III (headache and confusion) SAH, from a true PCoA on the right. He had a left subclavian artery occlusion with flow theft from the right vertebral artery to the left vertebral artery. The patient underwent endovascular treatment with angioplasty and stent placement on the left subclavian artery that resulted in aneurysm occlusion. In conclusion, despite their seldom occurrence, true PCoA aneurysms can be successfully treated with different strategies.

  10. True resolution enhancement for optical spectroscopy

    Science.gov (United States)

    Cooper, Justin T.; Oleske, Jeffrey B.

    2018-02-01

    Resolving spectrally adjacent peaks is important for techniques, such as tracking small shifts in Raman or fluorescence spectra, quantifying pharmaceutical polymorph ratios, or molecular orientation studies. Thus, suitable spectral resolution is a vital consideration when designing most spectroscopic systems. Most parameters that influence spectral resolution are fixed for a given system (spectrometer length, grating groove density, excitation source, CCD pixel size, etc.). Inflexible systems are non-problematic if the spectrometer is dedicated for a single purpose; however, these specifications cannot be optimized for different applications with wider range resolution requirements. Data processing techniques, including peak fitting, partial least squares, or principal component analysis, are typically used to achieve sub-optical resolution information. These techniques can be plagued by spectral artifacts introduced by post-processing as well as the subjective implementation of statistical parameters. TruRes™, from Andor Technology, uses an innovative optical means to greatly improve and expand the range of spectral resolutions accessible on a single setup. True spectral resolution enhancement of >30% is achieved without mathematical spectral alteration, dataprocessing, or spectrometer component changes. Discreet characteristic spectral lines from Laser-Induced Breakdown Spectroscopy (LIBS) and atomic calibration sources are now fully resolved from spectrally-adjacent peaks under otherwise identical configuration. TruRes™ has added advantage of increasing the spectral resolution without sacrificing bandpass. Using TruRes™ the Kymera 328i resolution can approach that of a 500 mm focal spectrometer. Furthermore, the bandpass of a 500 mm spectrograph with would be 50% narrower than the Kymera 328i with all other spectrometer components constant. However, the Kymera 328i with TruRes™ is able to preserve a 50% wider bandpass.

  11. Value judgments and the true self.

    Science.gov (United States)

    Newman, George E; Bloom, Paul; Knobe, Joshua

    2014-02-01

    The belief that individuals have a "true self" plays an important role in many areas of psychology as well as everyday life. The present studies demonstrate that people have a general tendency to conclude that the true self is fundamentally good--that is, that deep inside every individual, there is something motivating him or her to behave in ways that are virtuous. Study 1 finds that observers are more likely to see a person's true self reflected in behaviors they deem to be morally good than in behaviors they deem to be bad. Study 2 replicates this effect and demonstrates observers' own moral values influence what they judge to be another person's true self. Finally, Study 3 finds that this normative view of the true self is independent of the particular type of mental state (beliefs vs. feelings) that is seen as responsible for an agent's behavior.

  12. Performance measurement of PSF modeling reconstruction (True X) on Siemens Biograph TruePoint TrueV PET/CT.

    Science.gov (United States)

    Lee, Young Sub; Kim, Jin Su; Kim, Kyeong Min; Kang, Joo Hyun; Lim, Sang Moo; Kim, Hee-Joung

    2014-05-01

    The Siemens Biograph TruePoint TrueV (B-TPTV) positron emission tomography (PET) scanner performs 3D PET reconstruction using a system matrix with point spread function (PSF) modeling (called the True X reconstruction). PET resolution was dramatically improved with the True X method. In this study, we assessed the spatial resolution and image quality on a B-TPTV PET scanner. In addition, we assessed the feasibility of animal imaging with a B-TPTV PET and compared it with a microPET R4 scanner. Spatial resolution was measured at center and at 8 cm offset from the center in transverse plane with warm background activity. True X, ordered subset expectation maximization (OSEM) without PSF modeling, and filtered back-projection (FBP) reconstruction methods were used. Percent contrast (% contrast) and percent background variability (% BV) were assessed according to NEMA NU2-2007. The recovery coefficient (RC), non-uniformity, spill-over ratio (SOR), and PET imaging of the Micro Deluxe Phantom were assessed to compare image quality of B-TPTV PET with that of the microPET R4. When True X reconstruction was used, spatial resolution was RC with True X reconstruction was higher than that with the FBP method and the OSEM without PSF modeling method on the microPET R4. The non-uniformity with True X reconstruction was higher than that with FBP and OSEM without PSF modeling on microPET R4. SOR with True X reconstruction was better than that with FBP or OSEM without PSF modeling on the microPET R4. This study assessed the performance of the True X reconstruction. Spatial resolution with True X reconstruction was improved by 45 % and its % contrast was significantly improved compared to those with the conventional OSEM without PSF modeling reconstruction algorithm. The noise level was higher than that with the other reconstruction algorithm. Therefore, True X reconstruction should be used with caution when quantifying PET data.

  13. Responding to the Challenge of True Uncertainty

    DEFF Research Database (Denmark)

    Hallin, Carina Antonia; Andersen, Torben Juul

    We construe a conceptual framework for responding effectively to true uncertainty in the business environment. We drill down to the essential micro-foundational capabilities - sensing and seizing of dynamic capabilities - and link them to classical strategic issue management theory with suggestions...... on how to operationalize these essential capabilities. By definition true uncertainty represents environmental conditions that are hard to foresee, which can catch the unprepared by surprise while presenting opportunities to the conscious organization. We demonstrate that organizations relying...

  14. Studies on the true coincidence correction in measuring filter samples by gamma spectrometry

    CERN Document Server

    Lian Qi; Chang Yong Fu; Xia Bing

    2002-01-01

    The true coincidence correction in measuring filter samples has been studied by high efficiency HPGe gamma detectors. The true coincidence correction for a specific three excited levels de-excitation case has been analyzed, and the typical analytical expressions of true coincidence correction factors have been given. According to the measured relative efficiency on the detector surface with 8 'single' energy gamma emitters and efficiency of filter samples, the peak and total efficiency surfaces are fitted. The true coincidence correction factors of sup 6 sup 0 Co and sup 1 sup 5 sup 2 Eu calculated by the efficiency surfaces agree well with experimental results

  15. True polar wander on convecting planets

    Science.gov (United States)

    Rose, Ian Robert

    Rotating planets are most stable when spinning around their maximum moment of inertia, and will tend to reorient themselves to achieve this configuration. Geological activity redistributes mass in the planet, making the moment of inertia a function of time. As the moment of inertia of the planet changes, the spin axis shifts with respect to a mantle reference frame in order to maintain rotational stability. This process is known as true polar wander (TPW). Of the processes that contribute to a planet's moment of inertia, convection in the mantle generates the largest and longest-period fluctuations, with corresponding shifts in the spin axis. True polar wander has been hypothesized to explain several physiographic features on planets and moons in our solar system. On Earth, TPW events have been invoked in some interpretations of paleomagnetic data. Large swings in the spin axis could have enormous ramifications for paleogeography, paleoclimate, and the history of life. Although the existence of TPW is well-verified, it is not known whether its rate and magnitude have been large enough for it to be an important process in Earth history. If true polar wander has been sluggish compared to plate tectonic speeds, then it would be difficult to detect and its consequences would be minor. I investigate rates of true polar wander on convecting planets using scaling, numerics, and inverse problems. I perform a scaling analysis of TPW on a convecting planet, identifying a minimal set of nondimensional parameters which describe the problem. The primary nondimensional numbers that control the rate of TPW are the ratio of centrifugal to gravitational forces m and the Rayleigh number Ra. The parameter m sets the size of a planet's rotational bulge, which determines the amount of work that needs to be done to move the spin axis. The Rayleigh number controls the size, distribution, and rate of change of moment of inertia anomalies, all of which affect the rate of TPW. I find that

  16. 5-O T AFISI-IS AFRICAN SCIENCE A TRUE SCIENCE-FT- VOL 5 ...

    African Journals Online (AJOL)

    JONATHAN

    extinguishes the idea of a single self-consistent mode of rationality that could be universalized. .... verification principle to demarcate science from non-science. ... true scientific attitude, according to Popper, is witnessed in Newton's theory of.

  17. Representations built from a true geographic database

    DEFF Research Database (Denmark)

    Bodum, Lars

    2005-01-01

    the whole world in 3d and with a spatial reference given by geographic coordinates. Built on top of this is a customised viewer, based on the Xith(Java) scenegraph. The viewer reads the objects directly from the database and solves the question about Level-Of-Detail on buildings, orientation in relation...... a representation based on geographic and geospatial principles. The system GRIFINOR, developed at 3DGI, Aalborg University, DK, is capable of creating this object-orientation and furthermore does this on top of a true Geographic database. A true Geographic database can be characterized as a database that can cover...

  18. True ternary fission in 310126X

    International Nuclear Information System (INIS)

    Banupriya, B.; Vijayaraghavan, K.R.; Balasubramaniam, M.

    2015-01-01

    All possible combinations are minimized by the two dimensional minimization process and minimized with respect to neutron numbers and proton numbers of the fragments. Potential energy is low and Q - value is high at true ternary fission region. It shows that true ternary mode is the dominant mode in the ternary fission of superheavy nuclei. Also, the results show that the fragments with neutron magic numbers are the dominant one in the ternary fission of superheavy nuclei whereas the fragments with proton magic numbers are the dominant one in the ternary fission of heavy nuclei

  19. Registration of global cardiac function with real-time trueFISP in one respiratory cycle

    International Nuclear Information System (INIS)

    Wintersperger, B.J.; Nikolaou, K.; Huber, A.; Dietrich, O.; Reiser, M.F.; Schoenberg, S.O.; Muehling, O.; Nittka, M.; Kiefer, B.

    2004-01-01

    Real-time multislice cine techniques lead to inaccurate results in ventricular volumes based on limited temporal resolution. The purpose of the study is to evaluate a real-time cine technique with parallel imaging algorithms in comparison to standard segmented techniques. Twelve patients underwent cardiac cine MRI using real-time multislice cine trueFISP. Temporal resolution was improved using parallel acquisition techniques (iPAT) and data acquisition was performed in a single breath-hold along the patients' short axis. Evaluation of EDV, ESV, EF and myocardial mass was performed and results compared to a standard segmented single-slice cine trueFISP. Combination of real-time cine trueFISP and iPAT provided a temporal resolution of 48 ms. Results of the multislice approach showed an excellent correlation to standard single-slice trueFISP for EDV (0.94, p [de

  20. Chemical composition, true metabolisable energy content and ...

    African Journals Online (AJOL)

    The physical characteristics (thousand seed and hectolitre mass), chemical composition (dry matter, ash, crude protein (CP), ether extract, acid detergent fibre, neutral detergent fibre and mineral content), energy values (nitrogen corrected true metabolisable energy content (TMEn for roosters)) as well as the lysine and ...

  1. True fir spacing trials: 10-year results.

    Science.gov (United States)

    Robert O. Curtis

    2008-01-01

    Eighteen precommercial thinning trials were established in true fir-hemlock stands in the Olympic Mountains and the west side of the Cascade Range during the period 1987 through 1994. This paper updates a previous report, with results for the first 10 years after establishment. Results are given for (1) all trees, (2) the largest 80 per acre of any species, and (3)...

  2. Knowledge as Fact-Tracking True Belief

    Directory of Open Access Journals (Sweden)

    Fred Adams

    Full Text Available ABSTRACT Drawing inspiration from Fred Dretske, L. S. Carrier, John A. Barker, and Robert Nozick, we develop a tracking analysis of knowing according to which a true belief constitutes knowledge if and only if it is based on reasons that are sensitive to the fact that makes it true, that is, reasons that wouldn’t obtain if the belief weren’t true. We show that our sensitivity analysis handles numerous Gettier-type cases and lottery problems, blocks pathways leading to skepticism, and validates the epistemic closure thesis that correct inferences from known premises yield knowledge of the conclusions. We discuss the plausible views of Ted Warfield and Branden Fitelson regarding cases of knowledge acquired via inference from false premises, and we show how our sensitivity analysis can account for such cases. We present arguments designed to discredit putative counterexamples to sensitivity analyses recently proffered by Tristan Haze, John Williams and Neil Sinhababu, which involve true statements made by untrustworthy informants and strange clocks that sometimes display the correct time while running backwards. Finally, we show that in virtue of employing the paradox-free subjunctive conditionals codified by Relevance Logic theorists instead of the paradox-laden subjunctive conditionals codified by Robert Stalnaker and David Lewis.

  3. Is It True That Smoking Causes Wrinkles?

    Science.gov (United States)

    Healthy Lifestyle Quit smoking Is it true that smoking causes wrinkles? Answers from J. Taylor Hays, M.D. Yes. So if you need another reason to motivate ... elastin, which are fibers that give your skin its strength and elasticity. As a result, skin begins ...

  4. Chemical composition, true metabolisable energy content and ...

    African Journals Online (AJOL)

    aneldavh

    116. Chemical composition, true metabolisable energy content and amino acid availability of grain legumes for poultry. T.S. Brand. 1, 2,3#. , D.A. Brandt. 1, 2,4 and C.W. ... alternatives (Wiseman, 1987; Brand et al., 1995). ..... The Ca, P and trace element concentrations for lupins, faba beans and peas recorded in the present.

  5. True Faith in Faith and Knowledge

    NARCIS (Netherlands)

    Jonkers, P.H.A.I.

    2003-01-01

    This article deals with the diverging conceptions of faith that Hegel discusses in his essay Faith and Knowledge (1802). In order to modify the usual, negative image of Hegel’s attitude towards faith, which stresses its reflective character, I analyze his idea of a ‘true faith’. My conclusion is

  6. True to Yourself Leading a Values-Based Business

    CERN Document Server

    Albion, Mark

    2006-01-01

    How do you build the kind of company you've always wanted to work in--one that serves people and the planet while being financially successful, too? What do you do when you believe that business should serve the common good, but everyday business pressures--meeting payroll, battling competition, keeping customers and investors happy--are at a fever pitch? Leading a small business when you measure success more broadly than with a single financial bottom line is no easy task. True to Yourself is a practical guide to doing just that. It provides tools you can use to combine profit with purpose, m

  7. The incidence and prognosis of true duodenal carcinomas

    DEFF Research Database (Denmark)

    Buchbjerg, Thomas; Fristrup, C.; Mortensen, M. B.

    2015-01-01

    the criteria for true PDC. The incidence was 5.4 per 1,000,000, and the pathological classification was: Adenocarcinoma 87%, mucinous adenocarcinoma 7%, carcinoma 4% and signet ring cell carcinoma 1%. Intended curative resection was performed in 28 patients (39%) (22 Whipple procedures and 6 local resections......), and all but one patient had negative resection margins. Thirteen patients (46%) had lymph node metastasis. Twenty-nine (67%) of the palliative treated patients had a single (n = 24) or double by-pass procedure (n = 5). The median and 5-year survival for the resected patients were 23 months (CI 7...

  8. True ternary fission of 252Cf

    International Nuclear Information System (INIS)

    Vijayaraghavan, K.R.; Balasubramaniam, M.; Oertzen, W. von

    2014-01-01

    Splitting of heavy radioactive nucleus into three fragments is known as ternary fission. If the size of the fragments are almost equal it is referred to as true ternary fission. Recently, Yu. V. Pyatkov et al observed/reported the experimental observation of true ternary fission in 252 Cf. In this work, the possibilities of different true ternary fission modes of 252 Cf through potential energy surface (PES) calculations based on three cluster model (TCM) are discussed. In TCM a condition on the mass numbers of the fission fragments is implied as A 1 ≥ A 2 ≥ A 3 in order to avoid repetition of combinations. Due to this condition, the values of Z 3 vary from 0 to 36 and Z 2 vary from 16 to 51. Of the different pairs having similar (Z 2 , Z 3 ) with different potential energy, a pair possessing minimum potential energy is chosen. Thus identified favourable combinations are plotted. For the PES calculations the arrangement of the fragments is considered in the order of A 1 +A 2 +A 3 . i.e. the heavy and the lightest fragments are kept at the ends. It is seen that the deepest minimum in the PES occurs for Z 3 =2 labelled as (Z 2 ; 2) indicating He accompanied breakup as the most favourable one. Of which, the breakup with Z 2 around 46 to 48 is the least (shown by dashed (Z 1 = 50) and dotted (Z 1 = 52) lines indicating a constant Z 1 value). The other notable minima in the PES are labelled and they correspond to the (Z 2 , Z 3 ) pairs viz., (20, 20), (28, 20), (28, 28) and (32, 32). Of these four minima, the first three are associated with the magic numbers 20 and 28. For Z 3 =20, there are two minimums at (20,20) and (28,20) among them (28,20) is the lowest minimum through which the minimum-path passes, and it is the ternary decay observed by Yu. V. Pyatkov et al. The fourth minima is the most interesting due to the fact that it corresponds to true ternary fission mode with Z 2 =32, Z 3 =32 and Z 1 =34. The minimum potential energy path also goes through this true

  9. Cosmic chirality both true and false.

    Science.gov (United States)

    Barron, Laurence D

    2012-12-01

    The discrete symmetries of parity P, time reversal T, and charge conjugation C may be used to characterize the properties of chiral systems. It is well known that parity violation infiltrates into ordinary matter via an interaction between the nucleons and electrons, mediated by the Z(0) particle, that lifts the degeneracy of the mirror-image enantiomers of a chiral molecule. Being odd under P but even under T, this P-violating interaction exhibits true chirality and so may induce absolute enantioselection under all circumstances. It has been suggested that CP violation may also infiltrate into ordinary matter via a P-odd, T-odd interaction mediated by the (as yet undetected) axion. This CP-violating interaction exhibits false chirality and so may induce absolute enantioselection in processes far from equilibrium. Both true and false cosmic chirality should be considered together as possible sources of homochirality in the molecules of life. Copyright © 2012 Wiley Periodicals, Inc.

  10. Breaking the Barriers to True Augmented Reality

    OpenAIRE

    Sandor, Christian; Fuchs, Martin; Cassinelli, Alvaro; Li, Hao; Newcombe, Richard; Yamamoto, Goshiro; Feiner, Steven

    2015-01-01

    In recent years, Augmented Reality (AR) and Virtual Reality (VR) have gained considerable commercial traction, with Facebook acquiring Oculus VR for \\$2 billion, Magic Leap attracting more than \\$500 million of funding, and Microsoft announcing their HoloLens head-worn computer. Where is humanity headed: a brave new dystopia-or a paradise come true? In this article, we present discussions, which started at the symposium "Making Augmented Reality Real", held at Nara Institute of Science and Te...

  11. Frege on Truths, Truth and the True

    Directory of Open Access Journals (Sweden)

    Wolfgang Künne

    2008-08-01

    Full Text Available The founder of modern logic and grandfather of analytic philosophy was 70 years old when he published his paper 'Der Gedanke' (The Thought in 1918. This essay contains some of Gottlob Frege's deepest and most provocative reflections on the concept of truth, and it will play a prominent role in my lectures. The plan for my lectures is as follows. What is it that is (primarily true or false? 'Thoughts', is Frege's answer. In §1, I shall explain and defend this answer. In §2, I shall briefly consider his enthymematic argument for the conclusion that the word 'true' resists any attempt at defining it. In §3, I shall discuss his thesis that the thought that things are thus and so is identical with the thought that it is true that things are thus and so. The reasons we are offered for this thesis will be found wanting. In §4, I shall comment extensively on Frege's claim that, in a non-formal language like the one I am currently trying to speak, we can say whatever we want to say without ever using the word 'true' or any of its synonyms. I will reject the propositional-redundancy claim, endorse the assertive-redundancy claim and deny the connection Frege ascribes to them. In his classic 1892 paper 'Über Sinn und Bedeutung' (On Sense and Signification Frege argues that truth-values are objects. In §5, I shall scrutinize his argument. In §6, I will show that in Frege's ideography (Begriffsschrift truth, far from being redundant, is omnipresent. The final §7 is again on truth-bearers, this time as a topic in the theory of intentionality and in metaphysics. In the course of discussing Frege's views on the objecthood, the objectivity of thoughts and the timelessness of truth(s, I will plead for a somewhat mitigated Platonism.

  12. A True Open-Loop Synchronization Technique

    DEFF Research Database (Denmark)

    Golestan, Saeed; Vidal, Ana; Yepes, Alejandro G.

    2016-01-01

    Synchronization techniques can be broadly classified into two major categories: Closed-loop and open-loop methods. The open-loop synchronization (OLS) techniques, contrary to the closed-loop ones, are unconditionally stable and benefit from a fast dynamic response. Their performance, however, tends...... is to develop a true OLS (and therefore, unconditionally stable) technique without any need for the calculation of sine and cosine functions. The effectiveness of the proposed synchronization technique is confirmed through the simulation and experimental results....

  13. True amplitude wave equation migration arising from true amplitude one-way wave equations

    Science.gov (United States)

    Zhang, Yu; Zhang, Guanquan; Bleistein, Norman

    2003-10-01

    One-way wave operators are powerful tools for use in forward modelling and inversion. Their implementation, however, involves introduction of the square root of an operator as a pseudo-differential operator. Furthermore, a simple factoring of the wave operator produces one-way wave equations that yield the same travel times as the full wave equation, but do not yield accurate amplitudes except for homogeneous media and for almost all points in heterogeneous media. Here, we present augmented one-way wave equations. We show that these equations yield solutions for which the leading order asymptotic amplitude as well as the travel time satisfy the same differential equations as the corresponding functions for the full wave equation. Exact representations of the square-root operator appearing in these differential equations are elusive, except in cases in which the heterogeneity of the medium is independent of the transverse spatial variables. Here, we address the fully heterogeneous case. Singling out depth as the preferred direction of propagation, we introduce a representation of the square-root operator as an integral in which a rational function of the transverse Laplacian appears in the integrand. This allows us to carry out explicit asymptotic analysis of the resulting one-way wave equations. To do this, we introduce an auxiliary function that satisfies a lower dimensional wave equation in transverse spatial variables only. We prove that ray theory for these one-way wave equations leads to one-way eikonal equations and the correct leading order transport equation for the full wave equation. We then introduce appropriate boundary conditions at z = 0 to generate waves at depth whose quotient leads to a reflector map and an estimate of the ray theoretical reflection coefficient on the reflector. Thus, these true amplitude one-way wave equations lead to a 'true amplitude wave equation migration' (WEM) method. In fact, we prove that applying the WEM imaging condition

  14. True vaginal prolapse in a bitch.

    Science.gov (United States)

    Alan, M; Cetin, Y; Sendag, S; Eski, F

    2007-08-01

    Frequently, vaginal fold prolapse is the protrusion of edematous vaginal tissue into and through the opening of the vulva occurring during proestrus and estrus stages of the sexual cycle. True vaginal prolapse may occur near parturition, as the concentration of serum progesterone declines and the concentration of serum oestrogen increases. In the bitch, this type of true vaginal prolapse is a very rare condition. This short communication describes a 5-year-old female, cross-breed dog in moderate condition, weighing 33 kg, with distocia and true vaginal prolapse. Abdominal palpation and transabdominal ultrasonography revealed live and dead foetuses in the uterine horns. One dead and four live fetuses were removed from uterus by cesarean section. The ovariohysterectomy was performed after repositioning the vaginal wall with a combination of traction from within the abdomen and external manipulation through the vulva. Re-occurrence of a vaginal prolapse was not observed and the bitch recovered completely after the surgical therapy. Compared to other vaginal disorders, vaginal prolapse is an uncommon condition in the bitch. In the present case, extreme tenesmus arising from distocia may have predisposed to the vaginal prolapse. The cause of dystocia was probably the disposition of the first foetus. We concluded that the vaginal prolapse was the result of dystocia in the present case.

  15. True bilateral nasopharyngeal angiofibroma: report and review.

    Science.gov (United States)

    Mishra, Anupam; Mishra, Subhash Chandra

    2016-10-01

    This report describes the third case of a true bilateral Juvenile nasopharyngeal angiofibroma (JNA), i.e. two separate JNA arising from both sides simultaneously. The associated multiple recurrences in such a case have not yet been reported. A 21-year-man underwent transpalatal excision and recurred twice. The last 'neo-occurrence' encountered after 2 years was at a different site and was subsequently managed by post-embolization endoscopic resection. A complete report of its clinico-radiological features and management outcome is discussed.

  16. On a true value of risk

    DEFF Research Database (Denmark)

    Kozin, Igor

    2018-01-01

    The paper suggests looking on probabilistic risk quantities and concepts through the prism of accepting one of the views: whether a true value of risk exists or not. It is argued that discussions until now have been primarily focused on closely related topics that are different from the topic...... intervals, the use of Byes rule, models of complete ignorance, hierarchical models of uncertainty, assignment of probabilities over possibility space and interpretation of derived probabilistic measures. Behavioural implications of favouring the either view are also briefly described....

  17. True HIV seroprevalence in Indian blood donors.

    Science.gov (United States)

    Choudhury, N; Ayagiri, A; Ray, V L

    2000-03-01

    The National AIDS Control Organization (NACO), the apex body for controlling AIDS in India, projected that HIV seroprevalence would increase from 7/1000 in 1995 to 21.2/1000 in 1997. A high incidence (8.2%) of HIV was observed in blood donors. This study was carried out to find out the true HIV positivity in Indian blood donors. Blood donors from our centre were followed for more than 5 years to determine the true HIV seroprevalence and our result was compared with similar studies from India. Voluntary and relative blood donors who visited the SGPGIMS, Lucknow, since 1993 to June 1998 were included. They were screened for HIV 1/2 by ELISA kits (WHO approved). First-time HIV-positive samples were preserved frozen for further study (stage-I). They were repeated in duplicate and retested with other kits. If found positive, the sample was labelled as ELISA positive (stage-II). ELISA-positive samples were confirmed by Western Blot (WB) at stage-III. A total of 65 288 donors were included and 834 (12.8/1000) were reactive at stage-I. But 1.1/1000 donors were found to be ELISA positive at stage-II, and 0.28/1000 donors were positive by WB at stage-III. The 'seropositivity' rate from the NACO was significantly (P commercial blood banks. The HIV prevalence of blood donors (and national prevalence) is to be reassessed.

  18. Benign cementoblastoma (true cementoma in a cat

    Directory of Open Access Journals (Sweden)

    Lenin A Villamizar-Martinez

    2016-01-01

    Full Text Available Case summary A 10-year-old castrated male domestic shorthair cat was presented for assessment of a gingival mass surrounding the left maxillary third and fourth premolar teeth. The mass was surgically removed by means of a marginal rim excision, and the tissue was submitted for histological assessment. It was identified as a benign cementoblastoma (true cementoma. There was proliferation of mineralized eosinophilic material with multiple irregularly placed lacunae and reversal lines, reminiscent of cementum. The cat recovered uneventfully from the anesthesia, and there was no evidence of tumor recurrence 6 months after surgery. Relevance and novel information Cementoblastomas (true cementomas in domestic animals are rare, with just a few reports in ruminants, monogastric herbivores and rodents. Cementoblastoma is considered a benign tumor that arises from the tooth root. The slow, expansive and constant growth that characterizes these masses may be accompanied by signs of oral discomfort and dysphagia. This case report is intended to increase knowledge regarding this tumor in cats and also highlights the importance of complete excision of the neoplasm. To our knowledge, there are no previous reports in the literature of cementoblastoma in the cat.

  19. True Nature of Supply Network Communication Structure

    Directory of Open Access Journals (Sweden)

    Lokhman Hakim bin Osman

    2016-04-01

    Full Text Available Globalization of world economy has altered the definition of organizational structure. Global supply chain can no longer be viewed as an arm-length structure. It has become more complex. The complexity demands deeper research and understanding. This research analyzed a structure of supply network in an attempt to elucidate the true structure of the supply network. Using the quantitative Social Network Analysis methodology, findings of this study indicated that, the structure of the supply network differs depending on the types of network relations. An important implication of these findings would be a more focus resource management upon network relationship development that is based on firms’ positions in the different network structure. This research also contributes to the various strategies of effective and efficient supply chain management.

  20. Hadronic vacuum polarization in true muonium

    Science.gov (United States)

    Lamm, Henry

    2017-01-01

    In order to reduce the theoretical uncertainty in the prediction, the leading-order hadronic vacuum polarization contribution to the hyperfine splitting of true muonium is reevaluated in two ways. A more complex pionic form factor and better estimates of the perturbative QCD contributions are used to study the model dependence of the previous calculation. The second, more accurate method directly integrates the Drell ratio R (s ) to obtain C1 ,HVP=-0.04874 (9 ) . This corresponds to an energy shift in the hyperfine splitting (HFS) of Δ EHFS,HVP μ=-8202 (16 ) MHz and represents a factor-of-50 reduction in the theoretical uncertainty from hadronic sources. We also compute the contribution in positronium, which is too small at present to detect.

  1. True Visions The Emergence of Ambient Intelligence

    CERN Document Server

    Aarts, Emile

    2006-01-01

    Ambient intelligence (AI) refers to a developing technology that will increasingly make our everyday environment sensitive and responsive to our presence. The AI vision requires technology invisibly embedded in our everyday surroundings, present whenever we need it that will lead to the seamless integration of lighting, sounds, vision, domestic appliances, and personal healthcare products to enhance our living experience. Written for the non-specialist seeking an authoritative but accessible overview of this interdisciplinary field, True Visions explains how the devices making up the AI world will operate collectively using information and intelligence hidden in the wireless network connecting them. Expert contributions address key AI components such as smart materials and textiles, system architecture, mobile computing, broadband communication, and underlying issues of human-environment interactions. It seeks to unify the perspectives of scientists from diverse backgrounds ranging from the physics of materia...

  2. True or False Customer Engagement Behaviour

    DEFF Research Database (Denmark)

    Haurum, Helle; Beckmann, Suzanne C.

    2014-01-01

    Customers’ engagement behaviours are considered an important source of value to the company. So far, the discussion has mainly been conceptual and focused on the company’s perspective. By adopting the customer’s perspective we investigated how customers perceive their service relationship...... encounters with a company, using in-depth interviews. We found the following key factors driving and explaining customers’ engagement behaviours: (1) transactions matter and inconsistent engagement behaviours are a reality, (2) mundane products and services are still highly relevant for customers, and (3......) different degrees of customer experience alignment with services and products exist. Moreover, the distinction between true and false engagement behaviours we suggest indeed is relevant and we could establish their mediating capabilities....

  3. The True Gravitational Degrees Of Freedom

    International Nuclear Information System (INIS)

    Murchadha, N. o

    2011-01-01

    More than 50 years ago it was realized that General Relativity could be expressed in Hamiltonian form. Unfortunately, just like electromagnetism and Yang-Mills theory, the Einstein equations split into evolution equations and constraints which complicates matters. The 4 constraints are expressions of the gauge freedom of the theory, general covariance. One can cleanly pose initial data for the gravitational field, but this data has to satisfy the constraints. To find the independent degrees of freedom, one needs to factor the initial data by the constraints. There are many ways of doing this. I can do so in such a way as to implement the model suggested by Poincare for a well-posed dynamical system: Pick a configuration space and give the free initial data as a point of the configuration space and a tangent vector at the same point. Now, the evolution equations should give a unique curve in the same configuration space. This gives a natural definition of what I call the true gravitational degrees of freedom. (author)

  4. True pancreaticoduodenal artery aneurysms: A decision analysis

    International Nuclear Information System (INIS)

    Takao, Hidemasa; Nojo, Takeshi; Ohtomo, Kuni

    2010-01-01

    Purpose: True pancreaticoduodenal artery aneurysms are rare. No definitive study evaluating the natural history of these lesions or their preferred method of treatment has been published. The purpose of this study was to evaluate the outcome of preventive treatment of unruptured pancreaticoduodenal artery aneurysms using a Markov model. Materials and methods: With the use of a Markov model, we performed a decision analysis to evaluate the outcome of preventive treatment of unruptured pancreaticoduodenal artery aneurysms. The risk of rupture and the mortality of preventive treatment are unknown. Therefore, we performed sensitivity analysis using these parameters. Effectiveness was measured in life expectancy. Results: For 80-year-old patients, preventive treatment was dominated by no treatment if mortality rates of preventive treatment were greater than 1.4%, greater than 2.6%, greater than 3.8%, and greater than 4.8% at annual rupture rates of 1%, 2%, 3%, and 4%, respectively. For 50-year-old patients, preventive treatment was dominated by no treatment if mortality rates of preventive treatment were greater than 3.3%, greater than 5.9%, greater than 8.0%, and greater than 9.7% at annual rupture rates of 1%, 2%, 3%, and 4%, respectively. Conclusion: The effectiveness of preventive treatment of unruptured pancreaticoduodenal artery aneurysms depends on the aneurysm rupture rate, mortality rate of preventive treatment, and patient age. Taking into account the effects of these parameters is important in making treatment decisions.

  5. Acquirement of true stress-strain curve using true fracture strain obtained by tensile test and FE analysis

    International Nuclear Information System (INIS)

    Lee, Kyoung Yoon; Kim, Tae Hyung; Lee, Hyung Yil

    2009-01-01

    In this work, we predict a true fracture strain using load-displacement curves from tensile test and Finite Element Analysis (FEA), and suggest a method for acquiring true Stress-Strain (SS) curves by predicted fracture strain. We first derived the true SS curve up to necking point from load-displacement curve. As the beginning, the posterior necking part of true SS curve is linearly extrapolated with the slope at necking point. The whole SS curve is then adopted for FE simulation of tensile test. The Bridgman factor or suitable plate correction factors are applied to pre and post FEA. In the load-true strain curve from FEA, the true fracture strain is determined as the matching point to test fracture load. The determined true strain is validated by comparing with test fracture strain. Finally, we complete the true SS curve by combining the prior necking part and linear part, the latter of which connects necking and predicted fracture points.

  6. Acquirement of true stress-strain curve using true fracture strain obtained by tensile test and FE analysis

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kyoung Yoon; Kim, Tae Hyung; Lee, Hyung Yil [Sogang University, Seoul (Korea, Republic of)

    2009-07-01

    In this work, we predict a true fracture strain using load-displacement curves from tensile test and Finite Element Analysis (FEA), and suggest a method for acquiring true Stress-Strain (SS) curves by predicted fracture strain. We first derived the true SS curve up to necking point from load-displacement curve. As the beginning, the posterior necking part of true SS curve is linearly extrapolated with the slope at necking point. The whole SS curve is then adopted for FE simulation of tensile test. The Bridgman factor or suitable plate correction factors are applied to pre and post FEA. In the load-true strain curve from FEA, the true fracture strain is determined as the matching point to test fracture load. The determined true strain is validated by comparing with test fracture strain. Finally, we complete the true SS curve by combining the prior necking part and linear part, the latter of which connects necking and predicted fracture points.

  7. Acquirement of True Stress-strain Curve Using True Fracture Strain Obtained by Tensile Test and FE Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kyoung Yoon; Lee, Hyung Yil [Sogang University, Seoul (Korea, Republic of); Kim, Tae Hyung [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2009-10-15

    In this work, we predict a true fracture strain using load-displacement curves from tensile test and finite element analysis (FEA), and suggest a method for acquiring true stress-strain (SS) curves by predicted fracture strain. We first derived the true SS curve up to necking point from load-displacement curve. As the beginning, the posterior necking part of true SS curve is linearly extrapolated with the slope at necking point. The whole SS curve is then adopted for FE simulation of tensile test. The Bridgman factor or suitable plate correction factors are applied to pre and post FEA. In the load-true strain curve from FEA, the true fracture strain is determined as the matching point to test fracture load. The determined true strain is validated by comparing with test fracture strain. Finally, we complete the true SS curve by combining the prior necking part and linear part, the latter of which connects necking and predicted fracture points.

  8. 'TrueCoinc' software utility for calculation of the true coincidence correction

    International Nuclear Information System (INIS)

    Sudar, S.

    2002-01-01

    The true coincidence correction plays an important role in the overall accuracy of the γ ray spectrometry especially in the case of present-day high volume detectors. The calculation of true coincidence corrections needs detailed nuclear structure information. Recently these data are available in computerized form from the Nuclear Data Centers through the Internet or on a CD-ROM of the Table of Isotopes. The aim has been to develop software for this calculation, using available databases for the levels data. The user has to supply only the parameters of the detector to be used. The new computer program runs under the Windows 95/98 operating system. In the framework of the project a new formula was prepared for calculating the summing out correction and calculation of the intensity of alias lines (sum peaks). The file converter for reading the ENDSF-2 type files was completed. Reading and converting the original ENDSF was added to the program. A computer accessible database of the X rays energies and intensities was created. The X ray emissions were taken in account in the 'summing out' calculation. Calculation of the true coincidence 'summing in' correction was done. The output was arranged to show independently two types of corrections and to calculate the final correction as multiplication of the two. A minimal intensity threshold can be set to show the final list only for the strongest lines. The calculation takes into account all the transitions, independently of the threshold. The program calculates the intensity of X rays (K, L lines). The true coincidence corrections for X rays were calculated. The intensities of the alias γ lines were calculated. (author)

  9. Fingerprint re-alignment: a solution based on the true fingerprint center point

    CSIR Research Space (South Africa)

    Msiza, IS

    2011-02-01

    Full Text Available Solution Based on the True Fingerprint Center Point Ishmael S. Msiza, Brain Leke-Betechuoh, and Tendani Malumedzha Biometrics Research Group ? Information Security CSIR, Modelling & Digital Science Unit Pretoria, Republic of South Africa e... with a pattern that belongs to the Tented Arch (TA) fingerprint class. Fingerprints that belong to the TA class have a single core and a single delta, with the core located almost directly above the delta, as depicted in figure 3 (b). Many singular...

  10. Improved Calibration Shows Images True Colors

    Science.gov (United States)

    2015-01-01

    Innovative Imaging and Research, located at Stennis Space Center, used a single SBIR contract with the center to build a large-scale integrating sphere, capable of calibrating a whole array of cameras simultaneously, at a fraction of the usual cost for such a device. Through the use of LEDs, the company also made the sphere far more efficient than existing products and able to mimic sunlight.

  11. The true costs of nuclear power

    International Nuclear Information System (INIS)

    Wallner, A.; Mraz, G.

    2013-01-01

    Worldwide, many nuclear power plants will be reaching the end of their lifetimes over the next few years. States must therefore decide now on the direction they intend to steer their energy policies. Possible options are the construction of new nuclear power plants, extending the lifetime of existing ones, or changing direction towards a sustainable energy future. Arguments put forward by the nuclear power lobby in favour of new builds are, on the one hand, the claim that nuclear power is low in CO2 emissions,1and on the other, that it is low cost. This paper examines the second claim and identifies the “true costs of nuclear power”. This paper provides an overview for the general reader and presents the most important aspects of “costs of nuclear power”, as well as sound information to contribute to discussions of this complex issue. The first part of this paper focuses on the costs of nuclear new-build: Approximately two thirds of electricity generation costs consist of fixed costs, the largest part of which covers the construction of the nuclear power plant (NPP) itself, including the interest rates (capital costs). Consequently, construction costs are a crucial factor in the overall cost of nuclear power. The issue of nuclear new build is currently under discussion in many states in Europe which are considering replacing their aged nuclear power plant fleet, e.g. UK (Hinkley Point and further plans for new builds), Finland (Olkiluoto 3), France (Flamanville 3), the Czech Republic (Temelin 3/4), Slovakia (Mochovce 3/4) and Romania (Cernavoda 3/4). Those projects have one crucial point in common: problems with costs or financing. The Massachusetts Institute of Technology (MIT) has calculated that construction costs rose 15% per annum from 2003 to 2009; construction costs rose from 2,000 to 4,000 USD, amounting to total construction costs of US$ 4 billion for a 1,000 MW NPP. A current example of cost and construction time overrun is the Finnish reactor

  12. Solution-Processed Carbon Nanotube True Random Number Generator.

    Science.gov (United States)

    Gaviria Rojas, William A; McMorrow, Julian J; Geier, Michael L; Tang, Qianying; Kim, Chris H; Marks, Tobin J; Hersam, Mark C

    2017-08-09

    With the growing adoption of interconnected electronic devices in consumer and industrial applications, there is an increasing demand for robust security protocols when transmitting and receiving sensitive data. Toward this end, hardware true random number generators (TRNGs), commonly used to create encryption keys, offer significant advantages over software pseudorandom number generators. However, the vast network of devices and sensors envisioned for the "Internet of Things" will require small, low-cost, and mechanically flexible TRNGs with low computational complexity. These rigorous constraints position solution-processed semiconducting single-walled carbon nanotubes (SWCNTs) as leading candidates for next-generation security devices. Here, we demonstrate the first TRNG using static random access memory (SRAM) cells based on solution-processed SWCNTs that digitize thermal noise to generate random bits. This bit generation strategy can be readily implemented in hardware with minimal transistor and computational overhead, resulting in an output stream that passes standardized statistical tests for randomness. By using solution-processed semiconducting SWCNTs in a low-power, complementary architecture to achieve TRNG, we demonstrate a promising approach for improving the security of printable and flexible electronics.

  13. Estimating true evolutionary distances under the DCJ model.

    Science.gov (United States)

    Lin, Yu; Moret, Bernard M E

    2008-07-01

    Modern techniques can yield the ordering and strandedness of genes on each chromosome of a genome; such data already exists for hundreds of organisms. The evolutionary mechanisms through which the set of the genes of an organism is altered and reordered are of great interest to systematists, evolutionary biologists, comparative genomicists and biomedical researchers. Perhaps the most basic concept in this area is that of evolutionary distance between two genomes: under a given model of genomic evolution, how many events most likely took place to account for the difference between the two genomes? We present a method to estimate the true evolutionary distance between two genomes under the 'double-cut-and-join' (DCJ) model of genome rearrangement, a model under which a single multichromosomal operation accounts for all genomic rearrangement events: inversion, transposition, translocation, block interchange and chromosomal fusion and fission. Our method relies on a simple structural characterization of a genome pair and is both analytically and computationally tractable. We provide analytical results to describe the asymptotic behavior of genomes under the DCJ model, as well as experimental results on a wide variety of genome structures to exemplify the very high accuracy (and low variance) of our estimator. Our results provide a tool for accurate phylogenetic reconstruction from multichromosomal gene rearrangement data as well as a theoretical basis for refinements of the DCJ model to account for biological constraints. All of our software is available in source form under GPL at http://lcbb.epfl.ch.

  14. Material Properties Test to Determine Ultimate Strain and True Stress-True Strain Curves for High Yield Steels

    Energy Technology Data Exchange (ETDEWEB)

    K.R. Arpin; T.F. Trimble

    2003-04-01

    This testing was undertaken to develop material true stress-true strain curves for elastic-plastic material behavior for use in performing transient analysis. Based on the conclusions of this test, the true stress-true strain curves derived herein are valid for use in elastic-plastic finite element analysis for structures fabricated from these materials. In addition, for the materials tested herein, the ultimate strain values are greater than those values cited as the limits for the elastic-plastic strain acceptance criteria for transient analysis.

  15. True and False Memories, Parietal Cortex, and Confidence Judgments

    Science.gov (United States)

    Urgolites, Zhisen J.; Smith, Christine N.; Squire, Larry R.

    2015-01-01

    Recent studies have asked whether activity in the medial temporal lobe (MTL) and the neocortex can distinguish true memory from false memory. A frequent complication has been that the confidence associated with correct memory judgments (true memory) is typically higher than the confidence associated with incorrect memory judgments (false memory).…

  16. Effect of caecectomy on true metabolizable energy and lysine ...

    African Journals Online (AJOL)

    True metabolizable energy, conected for nitrogen retention. cfMEx) and true rysine avilabiliry, was determined for maize and sunflower oilcake o,?, t*o ,u*ii"s of each, *O in-r*ples of fishmeal, soyabean oilcake -"ur -a sorghum meal using intact and caecectomized roosters. The roosters were allowed ad tibitum intake over a ...

  17. True Umbilical Cord Knot Leading to Fetal Demise | Ikechebelu ...

    African Journals Online (AJOL)

    The incidence of true knot of the umbilical cord is not only very low but it is often undiagnosed antenatally when present despite the availability of prenatal ultrasonography. When the true knot remains tight, it may impede the circulation of the fetus and may result to fetal death in utero especially in labor. We report a very ...

  18. True self-alienation positively predicts reports of mindwandering.

    Science.gov (United States)

    Vess, Matthew; Leal, Stephanie A; Hoeldtke, Russell T; Schlegel, Rebecca J; Hicks, Joshua A

    2016-10-01

    Two studies assessed the relationship between feelings of uncertainty about who one truly is (i.e., true self-alienation) and self-reported task-unrelated thoughts (i.e., mindwandering) during performance tasks. Because true self-alienation is conceptualized as the subjective disconnect between conscious awareness and actual experience, we hypothesized that greater feelings of true self-alienation would positively relate to subjective reports of mindwandering. Two convergent studies supported this hypothesis. Moreover, this relationship could not consistently be accounted for by the independent influence of other aspects of authenticity, negative mood, mindfulness, or broad personality dimensions. These findings suggest that individual differences in true self-alienation are reliably associated with subjective reports of mindwandering. The implications of these findings for the true self-alienation construct, the ways that personality relates to mindwandering, and future research directions focused on curtailing mindwandering and improving performance and achievement are discussed. Copyright © 2016 Elsevier Inc. All rights reserved.

  19. A Case of True Hermaphroditism Presenting as a Testicular Tumour

    Directory of Open Access Journals (Sweden)

    Michelle Ceci

    2015-01-01

    Full Text Available True hermaphroditism represents only 5% cases of all of disorders of sexual differentiation (DSD and usually present in early childhood with ambiguous genitalia. Occasionally, cases might present later on in adolescence with problems of sexual maturation. Our case report presents a true hermaphrodite with normal male phenotype that presented as a left testicular mass, two years after being diagnosed with Sertoli cell only syndrome in the contralateral testis. Histological examination of the left testis showed ovarian, fallopian tube, myometrial, endometrial, and epididymal tissue. This combination of findings is found in approximately one-third of true hermaphrodites, but it is very rare to present clinically as an inguinoscrotal mass.

  20. The Dream Comes True in the Golden Hall

    Institute of Scientific and Technical Information of China (English)

    JianZhong; ChenJianguo

    2004-01-01

    Nanjing Traditional Music Ensemble has long dreamed of performing in Vienna's Golden Hall.Now the dream has come true.the whole troupe felt so exciting that they did not even sleep well during the flight.

  1. A True-False Test on Methods of Typewriting Instruction.

    Science.gov (United States)

    West, Leonard J.

    1984-01-01

    Presents a true-false test on typewriting instruction to illustrate the effects of educational lag, publishing practices, and deficiencies in preservice and inservice teacher education upon teaching methods. (SK)

  2. The True Self: A Psychological Concept Distinct From the Self.

    Science.gov (United States)

    Strohminger, Nina; Knobe, Joshua; Newman, George

    2017-07-01

    A long tradition of psychological research has explored the distinction between characteristics that are part of the self and those that lie outside of it. Recently, a surge of research has begun examining a further distinction. Even among characteristics that are internal to the self, people pick out a subset as belonging to the true self. These factors are judged as making people who they really are, deep down. In this paper, we introduce the concept of the true self and identify features that distinguish people's understanding of the true self from their understanding of the self more generally. In particular, we consider recent findings that the true self is perceived as positive and moral and that this tendency is actor-observer invariant and cross-culturally stable. We then explore possible explanations for these findings and discuss their implications for a variety of issues in psychology.

  3. The "True and fair view" concept in Lithuanian accounting regulation

    OpenAIRE

    Rudžionienė, Kristina; Christauskas, Česlovas

    2010-01-01

    The "true and fair view" concept is very popular in the professional accountants’ language. After theoretical analysis of the "true and fair view" concept it was made research how understanding of this concept was created in Lithuanian accounting regulation. The stated purpose of financial statements is taken from the United Kingdom, and is different in the particular formulation. Additionally, it is not explained anywhere what it is and how to reach it. There are not specifically defined qua...

  4. Measuring true localization accuracy in super resolution microscopy with DNA-origami nanostructures

    International Nuclear Information System (INIS)

    Reuss, Matthias; Blom, Hans; Brismar, Hjalmar; Fördős, Ferenc; Högberg, Björn; Öktem, Ozan

    2017-01-01

    A common method to assess the performance of (super resolution) microscopes is to use the localization precision of emitters as an estimate for the achieved resolution. Naturally, this is widely used in super resolution methods based on single molecule stochastic switching. This concept suffers from the fact that it is hard to calibrate measures against a real sample (a phantom), because true absolute positions of emitters are almost always unknown. For this reason, resolution estimates are potentially biased in an image since one is blind to true position accuracy, i.e. deviation in position measurement from true positions. We have solved this issue by imaging nanorods fabricated with DNA-origami. The nanorods used are designed to have emitters attached at each end in a well-defined and highly conserved distance. These structures are widely used to gauge localization precision. Here, we additionally determined the true achievable localization accuracy and compared this figure of merit to localization precision values for two common super resolution microscope methods STED and STORM. (paper)

  5. Study of CP -violating charge asymmetries of single muons and like-sign dimuons in ptrue'>p¯ collisions

    Energy Technology Data Exchange (ETDEWEB)

    Abazov, V. M.; Abbott, B.; Acharya, B. S.; Adams, M.; Adams, T.; Agnew, J. P.; Alexeev, G. D.; Alkhazov, G.; Alton, A.; Askew, A.; Atkins, S.; Augsten, K.; Avila, C.; Badaud, F.; Bagby, L.; Baldin, B.; Bandurin, D. V.; Banerjee, S.; Barberis, E.; Baringer, P.; Bartlett, J. F.; Bassler, U.; Bazterra, V.; Bean, A.; Begalli, M.; Bellantoni, L.; Beri, S. B.; Bernardi, G.; Bernhard, R.; Bertram, I.; Besançon, M.; Beuselinck, R.; Bhat, P. C.; Bhatia, S.; Bhatnagar, V.; Blazey, G.; Blessing, S.; Bloom, K.; Boehnlein, A.; Boline, D.; Boos, E. E.; Borissov, G.; Brandt, A.; Brandt, O.; Brock, R.; Bross, A.; Brown, D.; Bu, X. B.; Buehler, M.; Buescher, V.; Bunichev, V.; Burdin, S.; Buszello, C. P.; Camacho-Pérez, E.; Casey, B. C. K.; Castilla-Valdez, H.; Caughron, S.; Chakrabarti, S.; Chan, K. M.; Chandra, A.; Chapon, E.; Chen, G.; Cho, S. W.; Choi, S.; Choudhary, B.; Cihangir, S.; Claes, D.; Clutter, J.; Cooke, M.; Cooper, W. E.; Corcoran, M.; Couderc, F.; Cousinou, M. -C.; Cutts, D.; Das, A.; Davies, G.; de Jong, S. J.; De La Cruz-Burelo, E.; Déliot, F.; Demina, R.; Denisov, D.; Denisov, S. P.; Desai, S.; Deterre, C.; DeVaughan, K.; Diehl, H. T.; Diesburg, M.; Ding, P. F.; Dominguez, A.; Dubey, A.; Dudko, L. V.; Duperrin, A.; Dutt, S.; Eads, M.; Edmunds, D.; Ellison, J.; Elvira, V. D.; Enari, Y.; Evans, H.; Evdokimov, V. N.; Feng, L.; Ferbel, T.; Fiedler, F.; Filthaut, F.; Fisher, W.; Fisk, H. E.; Fortner, M.; Fox, H.; Fuess, S.; Garbincius, P. H.; Garcia-Bellido, A.; García-González, J. A.; Gavrilov, V.; Geng, W.; Gerber, C. E.; Gershtein, Y.; Ginther, G.; Golovanov, G.; Grannis, P. D.; Greder, S.; Greenlee, H.; Grenier, G.; Gris, Ph.; Grivaz, J. -F.; Grohsjean, A.; Grünendahl, S.; Grünewald, M. W.; Guillemin, T.; Gutierrez, G.; Gutierrez, P.; Haley, J.; Han, L.; Harder, K.; Harel, A.; Hauptman, J. M.; Hays, J.; Head, T.; Hebbeker, T.; Hedin, D.; Hegab, H.; Heinson, A. P.; Heintz, U.; Hensel, C.; Heredia-De La Cruz, I.; Herner, K.; Hesketh, G.; Hildreth, M. D.; Hirosky, R.; Hoang, T.; Hobbs, J. D.; Hoeneisen, B.; Hogan, J.; Hohlfeld, M.; Holzbauer, J. L.; Howley, I.; Hubacek, Z.; Hynek, V.; Iashvili, I.; Ilchenko, Y.; Illingworth, R.; Ito, A. S.; Jabeen, S.; Jaffré, M.; Jayasinghe, A.; Jeong, M. S.; Jesik, R.; Jiang, P.; Johns, K.; Johnson, E.; Johnson, M.; Jonckheere, A.; Jonsson, P.; Joshi, J.; Jung, A. W.; Juste, A.; Kajfasz, E.; Karmanov, D.; Katsanos, I.; Kehoe, R.; Kermiche, S.; Khalatyan, N.; Khanov, A.; Kharchilava, A.; Kharzheev, Y. N.; Kiselevich, I.; Kohli, J. M.; Kozelov, A. V.; Kraus, J.; Kumar, A.; Kupco, A.; Kurča, T.; Kuzmin, V. A.; Lammers, S.; Lebrun, P.; Lee, H. S.; Lee, S. W.; Lee, W. M.; Lei, X.; Lellouch, J.; Li, D.; Li, H.; Li, L.; Li, Q. Z.; Lim, J. K.; Lincoln, D.; Linnemann, J.; Lipaev, V. V.; Lipton, R.; Liu, H.; Liu, Y.; Lobodenko, A.; Lokajicek, M.; Lopes de Sa, R.; Luna-Garcia, R.; Lyon, A. L.; Maciel, A. K. A.; Madar, R.; Magaña-Villalba, R.; Malik, S.; Malyshev, V. L.; Mansour, J.; Martínez-Ortega, J.; McCarthy, R.; McGivern, C. L.; Meijer, M. M.; Melnitchouk, A.; Menezes, D.; Mercadante, P. G.; Merkin, M.; Meyer, A.; Meyer, J.; Miconi, F.; Mondal, N. K.; Mulhearn, M.; Nagy, E.; Narain, M.; Nayyar, R.; Neal, H. A.; Negret, J. P.; Neustroev, P.; Nguyen, H. T.; Nunnemann, T.; Orduna, J.; Osman, N.; Osta, J.; Pal, A.; Parashar, N.; Parihar, V.; Park, S. K.; Partridge, R.; Parua, N.; Patwa, A.; Penning, B.; Perfilov, M.; Peters, Y.; Petridis, K.; Petrillo, G.; Pétroff, P.; Pleier, M. -A.; Podstavkov, V. M.; Popov, A. V.; Prewitt, M.; Price, D.; Prokopenko, N.; Qian, J.; Quadt, A.; Quinn, B.; Ratoff, P. N.; Razumov, I.; Ripp-Baudot, I.; Rizatdinova, F.; Rominsky, M.; Ross, A.; Royon, C.; Rubinov, P.; Ruchti, R.; Sajot, G.; Sánchez-Hernández, A.; Sanders, M. P.; Santos, A. S.; Savage, G.; Sawyer, L.; Scanlon, T.; Schamberger, R. D.; Scheglov, Y.; Schellman, H.; Schwanenberger, C.; Schwienhorst, R.; Sekaric, J.; Severini, H.; Shabalina, E.; Shary, V.; Shaw, S.; Shchukin, A. A.; Simak, V.; Skubic, P.; Slattery, P.; Smirnov, D.; Snow, G. R.; Snow, J.; Snyder, S.; Söldner-Rembold, S.; Sonnenschein, L.; Soustruznik, K.; Stark, J.; Stoyanova, D. A.; Strauss, M.; Suter, L.; Svoisky, P.; Titov, M.; Tokmenin, V. V.; Tsai, Y. -T.; Tsybychev, D.; Tuchming, B.; Tully, C.; Uvarov, L.; Uvarov, S.; Uzunyan, S.; Van Kooten, R.; van Leeuwen, W. M.; Varelas, N.; Varnes, E. W.; Vasilyev, I. A.; Verkheev, A. Y.; Vertogradov, L. S.; Verzocchi, M.; Vesterinen, M.; Vilanova, D.; Vokac, P.; Wahl, H. D.; Wang, M. H. L. S.; Warchol, J.; Watts, G.; Wayne, M.; Weichert, J.; Welty-Rieger, L.; Williams, M. R. J.; Wilson, G. W.; Wobisch, M.; Wood, D. R.; Wyatt, T. R.; Xie, Y.; Yamada, R.; Yang, S.; Yasuda, T.; Yatsunenko, Y. A.; Ye, W.; Ye, Z.; Yin, H.; Yip, K.; Youn, S. W.; Yu, J. M.; Zennamo, J.; Zhao, T. G.; Zhou, B.; Zhu, J.; Zielinski, M.; Zieminska, D.; Zivkovic, L.

    2014-01-01

    We measure the inclusive single muon charge asymmetry and the like-sign dimuon charge asymmetry in $p \\bar{p}$ collisions using the full data set of 10.4 fb$^{-1}$ collected with the D0 detector at the Fermilab Tevatron. The standard model predictions of the charge asymmetries induced by CP violation are small in magnitude compared to the current experimental precision, so non-zero measurements could indicate new sources of CP violation. The measurements differ from the standard model predictions of CP violation in these asymmetries with a significance of 3.6 standard deviations. These results are interpreted in a framework of $B$ meson mixing within the CKM formalism to measure the relative width difference $\\dgg$ between the mass eigenstates of the $\\Bd$ meson system, and the semileptonic charge asymmetries $\\asld$ and $\\asls$ of $\\Bd$ and $\\Bs$ mesons respectively.

  6. True dreams: Encounter of the worlds in Islamic philosophy

    Directory of Open Access Journals (Sweden)

    Halilović Tehran

    2014-01-01

    Full Text Available True dreams that explicitly or symbolically reveal the events of the past and the future, in the ontological sense tell more than just about the content of a dream because they bespeak the supratemporal dimension of human beings and represent man's ability to connect to different worlds, and respectively multitudinous forms and levels of being. In this paper, without going into the psychological or physiological analysis of dreams, we try to clarify the ontological significance and position of true dreams in existing worlds. In Islamic philosophy, the underlying cognitive basis for the description of the ontological level of true dreams was established by the founder of Illuminative Philosophy, Shaykh al-Ishraq (1155-1191, and it was expanded by the founder of Transcendental Philosophy, Mulla Sadra Shirazi (1572-1640. Shaykh al-Ishraq explained in detail existential position of supramaterial beings that on the one hand are above the world of matter and in a direct active contact with it, and on the other hand, are under the dominant world of intellect. He called these creatures Midworld (Barzakh and, for the first time in Islamic philosophy, stated that it is a separate world of imagination that is different from the material and intelligible one. True dreams are one of the many indications that man has a supratemporal dimension that exposes supramaterial and temporally unlimited worlds to him. Apart from true dreams, most important signs of supramaterial worlds in human life are the prophetic revelation, as well as revelations and mystical-gnostic intuition. Unlike the last two examples, true dreams are known and accessible to all people, both from their immediate experience and from the stories of the ones close to them. For this reason, in this paper we explain how true dreams represent a blend of worlds in human life.

  7. Why should correction values be better known than the measurand true value?

    International Nuclear Information System (INIS)

    Pavese, Franco

    2013-01-01

    Since the beginning of the history of modern measurement science, the experimenters faced the problem of dealing with systematic effects, as distinct from, and opposed to, random effects. Two main schools of thinking stemmed from the empirical and theoretical exploration of the problem, one dictating that the two species should be kept and reported separately, the other indicating ways to combine the two species into a single numerical value for the total uncertainty (often indicated as 'error'). The second way of thinking was adopted by the GUM, and, generally, adopts the method of assuming that their expected value is null by requiring, for all systematic effects taken into account in the model, that corresponding 'corrections' are applied to the measured values before the uncertainty analysis is performed. On the other hand, about the value of the measurand intended to be the object of measurement, classical statistics calls it 'true value', admitting that a value should exist objectively (e.g. the value of a fundamental constant), and that any experimental operation aims at obtaining an ideally exact measure of it. However, due to the uncertainty affecting every measurement process, this goal can be attained only approximately, in the sense that nobody can ever know exactly how much any measured value differs from the true value. The paper discusses the credibility of the numerical value attributed to an estimated correction, compared with the credibility of the estimate of the location of the true value, concluding that the true value of a correction should be considered as imprecisely evaluable as the true value of any 'input quantity', and of the measurand itself. From this conclusion, one should derive that the distinction between 'input quantities' and 'corrections' is not justified and not useful

  8. The spread of true and false news online.

    Science.gov (United States)

    Vosoughi, Soroush; Roy, Deb; Aral, Sinan

    2018-03-09

    We investigated the differential diffusion of all of the verified true and false news stories distributed on Twitter from 2006 to 2017. The data comprise ~126,000 stories tweeted by ~3 million people more than 4.5 million times. We classified news as true or false using information from six independent fact-checking organizations that exhibited 95 to 98% agreement on the classifications. Falsehood diffused significantly farther, faster, deeper, and more broadly than the truth in all categories of information, and the effects were more pronounced for false political news than for false news about terrorism, natural disasters, science, urban legends, or financial information. We found that false news was more novel than true news, which suggests that people were more likely to share novel information. Whereas false stories inspired fear, disgust, and surprise in replies, true stories inspired anticipation, sadness, joy, and trust. Contrary to conventional wisdom, robots accelerated the spread of true and false news at the same rate, implying that false news spreads more than the truth because humans, not robots, are more likely to spread it. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

  9. The true cost of electric power. Summary for policymakers

    Energy Technology Data Exchange (ETDEWEB)

    Burtraw, Dallas; Knupnick, Alan [Resources for the Future, Washington, DC (United States). Center for Energy Economics and Policy

    2012-06-15

    This report examines the various methods that have been used to measure 'true' costs of electricity generation technologies and looks at how such estimates can be used in company decision-making and public policy to ensure that investments are directed at the electricity generation methods with the lowest true costs to investors and society. In some geographic areas, adequate data and methods exist to make a solid estimate of the total social costs of energy production. In those places where the data or methods (or both) are less robust, it is possible to use a benefits transfer approach that still gives stakeholders important guidance about the scale of the true costs of their investments and to get started in formulating policies to incorporate those costs into the market price.

  10. Optical True Time Delay for Phased Array Antennas Composed of 2×2 Optical MEMS Switches and Fiber Delay Lines

    Institute of Scientific and Technical Information of China (English)

    Back-Song; Lee; Jong-Dug; Shin; Boo-Gyoun; Kim

    2003-01-01

    We proposed an optical true time delay (TTD) for phased array antennas (PAAs) composed of 2×2 optical MEMS switches, single-mode fiber delay lines, and a fixed wavelength laser diode. A 3-bit TTD for 10 GHz PAAs was implemented with a time delay error less than ± 0.2 ps.

  11. Mood-congruent true and false memory: effects of depression.

    Science.gov (United States)

    Howe, Mark L; Malone, Catherine

    2011-02-01

    The Deese/Roediger-McDermott paradigm was used to investigate the effect of depression on true and false recognition. In this experiment true and false recognition was examined across positive, neutral, negative, and depression-relevant lists for individuals with and without a diagnosis of major depressive disorder. Results showed that participants with major depressive disorder falsely recognised significantly more depression-relevant words than non-depressed controls. These findings also parallel recent research using recall instead of recognition and show that there are clear mood congruence effects for depression on false memory performance. © 2011 Psychology Press, an imprint of the Taylor & Francis Group, an Informa business

  12. Posttraumatic True Aneurysm of the Axillary Artery Following Blunt Trauma

    Directory of Open Access Journals (Sweden)

    Tugrul Goncu

    2010-01-01

    Full Text Available The majority of the axillary artery aneurysm cases arise as pseudoaneurysms secondary to blunt or iatrogenic trauma. Isolated traumatic true axillary artery aneurysm is a relatively unusual disorder and generally occurs with repetitive blunt trauma. A 22-year-old female patient with distal axillary artery true aneurysm due to simple blunt axillothoracic trauma is presented. The aneurysm was excised with subpectoral-axillary approach and saphenous vein graft interposition was applied. Long-term follow-up with the patient was uneventful.

  13. Differentiating true and false schematic memories in older adults.

    Science.gov (United States)

    Webb, Christina E; Dennis, Nancy A

    2018-02-06

    While schemas aid memory for schematically related information, the gist induced by the schema can also lead to high rates of false memories, especially in older adults. The neural mechanisms that support and differentiate true and false memories in aging are not well understood. The current study sought to clarify this, using a novel scene paradigm to investigate the role of schemas on true and false memories in older adults. Healthy older adults encoded schematic scenes (e.g., bathroom). At retrieval, participants were tested on their memory for both schematic and non-schematic targets and lures while fMRI data was collected. Results indicate that true memories were supported by the typical retrieval network, and activity in this network was greater for true than false memories. Schema specific retrieval was supported by mPFC, extending this common finding to aging. While no region differentiated false memories compared to correct rejections, results showed that individual differences in false memory rates were associated with variability in neural activity. The findings underscore the importance of elucidating the neural basis of cognition within older adults, as well as the specific contribution of individual differences to the neural basis of memory errors in aging. © The Author(s) 2018. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  14. True Umbilical Cord Knot Leading to Fetal Demise

    African Journals Online (AJOL)

    weight was 140 kg, height 1.69 m, blood pressure 120 mmHg. The booking ... The fetal heart tones were monitored using Doppler sonicaid. They remained normal throughout .... true knot, seemingly because the umbilical cord vessels can be compressed ... Therefore, the Wharton's jelly surrounding the fetal vessels has the ...

  15. Endovascular treatment of ruptured true posterior communicating artery aneurysms.

    Science.gov (United States)

    Yang, Yonglin; Su, Wandong; Meng, Qinghai

    2015-01-01

    Although true posterior communicating artery (PCoA) aneurysms are rare, they are of vital importance. We reviewed 9 patients with this fatal disease, who were treated with endovascular embolization, and discussed the meaning of endovascular embolization for the treatment of true PCoA aneurysms. From September 2006 to May 2012, 9 patients with digital substraction angiography (DSA) confirmed true PCoA aneurysms were treated with endovascular embolization. Patients were followed-up with a minimal duration of 17 months and assessed by Glasgow Outcome Scale (GOS) score. All the patients presented with spontaneous subarachnoid hemorrhage from the ruptured aneurysms. The ratio of males to females was 1:2, and the average age of onset was 59.9 (ranging from 52 to 72) years. The preoperative Hunt-Hess grade scores were I to III. All patients had recovered satisfactorily. No permanent neurological deficits were left. Currently, endovascular embolization can be recommended as the top choice for the treatment of most true PCoA aneurysms, due to its advanced technique, especially the application of the stent-assisted coiling technique, combined with its advantage of mininal invasiveness and quick recovery. However, the choice of treatment methods should be based on the clinical and anatomical characteristics of the aneurysm and the skillfulness of the surgeon.

  16. Activation of Imaginal Information on True and False Memories

    Science.gov (United States)

    Chang, Sau Hou; Pierce, Benton H.

    2009-01-01

    The present study examined the activation of imaginal information on true and false memories. Participants studied a series of concrete objects in pictures or words. The imagery group (n = 96) was instructed to form images and the control group (n = 96) was not instructed to do so. Both groups were then given a standard recognition memory test and…

  17. Using Story Contexts to Bias Children's True and False Memories

    Science.gov (United States)

    Howe, Mark L.; Wilkinson, Samantha

    2011-01-01

    The effects of embedding standard Deese/Roediger-McDermott (DRM) lists into stories whose context biased interpretation either toward or away from the overall themes of the DRM lists on both true and false recognition were investigated with 7- and 11-year-olds. These biased story contexts were compared with the same children's susceptibility to…

  18. True navigation and magnetic maps in spiny lobsters.

    Science.gov (United States)

    Boles, Larry C; Lohmann, Kenneth J

    2003-01-02

    Animals are capable of true navigation if, after displacement to a location where they have never been, they can determine their position relative to a goal without relying on familiar surroundings, cues that emanate from the destination, or information collected during the outward journey. So far, only a few animals, all vertebrates, have been shown to possess true navigation. Those few invertebrates that have been carefully studied return to target areas using path integration, landmark recognition, compass orientation and other mechanisms that cannot compensate for displacements into unfamiliar territory. Here we report, however, that the spiny lobster Panulirus argus oriented reliably towards a capture site when displaced 12-37 km to unfamiliar locations, even when deprived of all known orientation cues en route. Little is known about how lobsters and other animals determine position during true navigation. To test the hypothesis that lobsters derive positional information from the Earth's magnetic field, lobsters were exposed to fields replicating those that exist at specific locations in their environment. Lobsters tested in a field north of the capture site oriented themselves southwards, whereas those tested in a field south of the capture site oriented themselves northwards. These results imply that true navigation in spiny lobsters, and perhaps in other animals, is based on a magnetic map sense.

  19. BMI may underestimate the socioeconomic gradient in true obesity

    NARCIS (Netherlands)

    van den Berg, G.; van Eijsden, M.; Vrijkotte, T. G. M.; Gemke, R. J. B. J.

    2013-01-01

    Body mass index (BMI) does not make a distinction between fat mass and lean mass. In children, high fat mass appears to be associated with low maternal education, as well as low lean mass because maternal education is associated with physical activity. Therefore, BMI might underestimate true obesity

  20. MR-Venography Using High Resolution True-FISP

    Energy Technology Data Exchange (ETDEWEB)

    Spuentrup, E. [Technische Hochschule Aachen (Germany). Klinik fuer Radiologische Diagnostik; Beth Israel Deaconess Medical Center, Boston, MA (United States). Dept. of Medicine; Harvard Medical School, Boston, MA (United States); Buecker, A.; Guenther, R.W. [Technische Hochschule Aachen (Germany). Klinik fuer Radiologische Diagnostik; Stuber, M. [Beth Israel Deaconess Medical Center, Boston, MA (United States). Dept. of Medicine; Harvard Medical School, Boston, MA (United States); Philips Med. Syst., Best (Netherlands)

    2001-08-01

    A new fast MR-venography approach using a high resolution True-FISP imaging sequence was investigated in 20 patients suffering from 23 deep vein thromboses. Diagnosis was proven by X-ray venography, CT or ultrasound examination. The presented technique allowed for clear thrombus visualization with a high contrast to the surrounding blood pool even in calf veins. Acquisition time was less than 10 minutes for imaging the pelvis and the legs. No contrast media was needed. The presented high resolution True-FISP MR-veography is a promising non-invasive, fast MR-venography approach for detection of deep venous thrombosis. (orig.) [German] Eine neue schnelle, oertlich hochaufgeloeste MR-Phlebographietechnik mit einer axialen True-FISP Bildgebungssequenz wurde an 20 Patienten mit 23 nach-gewiesenen tiefen Beinvenenthrombosen untersucht. Die Befunde wurden mit einer konventionellen Roentgenphlebographie, einer CT oder einer Sonographie gesichert. Die vorgestellte Technik erlaubte in allen Faellen eine Thrombusdarstellung mit hohem Kontrast zum umgebenden venoesen Blut, wobei aufgrund der hohen Ortsaufloesung auch die Unterschenkelvenen beurteilt werden konnten. Die Datenaufnahmezeit zur Untersuchung des Beckens und der Beine betrug weniger als 10 Minuten. Kontrastmittel wurde nicht benoetigt. Die vorgestellte MR-Phlebographietechnik unter Verwendung einer oertlich hochauf-geloesten True-FISP Sequenz ist eine neue, vielversprechende, nicht-invasive Technik zur Diagnostik der tiefen Bein- und Beckenvenenthrombose. (orig.)

  1. Molecular characterization of true morels (Morchella) in Turkey

    Science.gov (United States)

    A collection of 247 true morels (Morchella spp.) was made from 10 different provinces of Turkey during the 2007-2008 growing season. This collection was analyzed for species diversity using phylogenetic analyses of partial Ribonucleic acid (RNA) polymerase I (RPB1) and nuclear ribosomal large subuni...

  2. Detecting the True Nature of Allegations of Rape

    NARCIS (Netherlands)

    De Zutter, André; Horselenberg, Robert; van Koppen, Peter J.

    2017-01-01

    A study was conducted to test whether it is possible to build a model to distinguish true and false allegations of rape based on the theory of fabricated rape. The theory is based on the principle that a false complainant of rape has not been raped and has to fabricate a story while the story of a

  3. True fir-hemlock spacing trials: design and first results.

    Science.gov (United States)

    Robert O. Curtis; Gary W. Clendenen; Jan A. Henderson

    2000-01-01

    A series of 18 precommercial thinning trials was established in true fir-hemlock stands in the Olympic Mountains and along the west side of the Cascade Range in Washington and Oregon from 1987 through 1994. This paper documents establishment of these installations and presents some preliminary observations and results. Substantial differences in growth rates in height...

  4. True and Fair View: Incentive or Inhibitor for Creative Accounting?

    Directory of Open Access Journals (Sweden)

    Ciocan Claudia-Cătălina

    2017-01-01

    Full Text Available The objective of accounting is to present information about the financial position, changes forthe financial position and performance of an economic entity and the financial statements mustpresent a true and fair view of the economic reality for the enterprise concerned. Creativeaccounting is a present issue, a phenomenon that increases users mistrust in financial statements,being considered a manipulation of figures in order to obtain a favorable image, far from beingtrue. In order to address this issue, we analyzed several definitions and forms of this concept, andfollowed how they relate to the objective of the true and fair view. The paper points out that theinteraction between creative accounting and true and fair view can be regarded in a double way:on one side, taking into account the influence of creative accounting on the objective of the trueand fair view, and, on the other side, considering the influence of the perception of the true and fairview on the choice of these techniques.

  5. Search for s -Channel Single-Top-Quark Production in Events with Missing Energy Plus Jets in ptrue'>ptrue' stretchy='false'>¯ Collisions at s=1.96TeV

    Energy Technology Data Exchange (ETDEWEB)

    Aaltonen, T.; Amerio, S.; Amidei, D.; Anastassov, A.; Annovi, A.; Antos, J.; Apollinari, G.; Appel, J. A.; Arisawa, T.; Artikov, A.; Asaadi, J.; Ashmanskas, W.; Auerbach, B.; Aurisano, A.; Azfar, F.; Badgett, W.; Bae, T.; Barbaro-Galtieri, A.; Barnes, V. E.; Barnett, B. A.; Barria, P.; Bartos, P.; Bauce, M.; Bedeschi, F.; Behari, S.; Bellettini, G.; Bellinger, J.; Benjamin, D.; Beretvas, A.; Bhatti, A.; Bland, K. R.; Blumenfeld, B.; Bocci, A.; Bodek, A.; Bortoletto, D.; Boudreau, J.; Boveia, A.; Brigliadori, L.; Bromberg, C.; Brucken, E.; Budagov, J.; Budd, H. S.; Burkett, K.; Busetto, G.; Bussey, P.; Butti, P.; Buzatu, A.; Calamba, A.; Camarda, S.; Campanelli, M.; Canelli, F.; Carls, B.; Carlsmith, D.; Carosi, R.; Carrillo, S.; Casal, B.; Casarsa, M.; Castro, A.; Catastini, P.; Cauz, D.; Cavaliere, V.; Cavalli-Sforza, M.; Cerri, A.; Cerrito, L.; Chen, Y. C.; Chertok, M.; Chiarelli, G.; Chlachidze, G.; Cho, K.; Chokheli, D.; Clark, A.; Clarke, C.; Convery, M. E.; Conway, J.; Corbo, M.; Cordelli, M.; Cox, C. A.; Cox, D. J.; Cremonesi, M.; Cruz, D.; Cuevas, J.; Culbertson, R.; d’Ascenzo, N.; Datta, M.; de Barbaro, P.; Demortier, L.; Deninno, M.; D’Errico, M.; Devoto, F.; Di Canto, A.; Di Ruzza, B.; Dittmann, J. R.; Donati, S.; D’Onofrio, M.; Dorigo, M.; Driutti, A.; Ebina, K.; Edgar, R.; Elagin, A.; Erbacher, R.; Errede, S.; Esham, B.; Farrington, S.; Fernández Ramos, J. P.; Field, R.; Flanagan, G.; Forrest, R.; Franklin, M.; Freeman, J. C.; Frisch, H.; Funakoshi, Y.; Galloni, C.; Garfinkel, A. F.; Garosi, P.; Gerberich, H.; Gerchtein, E.; Giagu, S.; Giakoumopoulou, V.; Gibson, K.; Ginsburg, C. M.; Giokaris, N.; Giromini, P.; Giurgiu, G.; Glagolev, V.; Glenzinski, D.; Gold, M.; Goldin, D.; Golossanov, A.; Gomez, G.; Gomez-Ceballos, G.; Goncharov, M.; González López, O.; Gorelov, I.; Goshaw, A. T.; Goulianos, K.; Gramellini, E.; Grinstein, S.; Grosso-Pilcher, C.; Group, R. C.; Guimaraes da Costa, J.; Hahn, S. R.; Han, J. Y.; Happacher, F.; Hara, K.; Hare, M.; Harr, R. F.; Harrington-Taber, T.; Hatakeyama, K.; Hays, C.; Heinrich, J.; Herndon, M.; Hocker, A.; Hong, Z.; Hopkins, W.; Hou, S.; Hughes, R. E.; Husemann, U.; Hussein, M.; Huston, J.; Introzzi, G.; Iori, M.; Ivanov, A.; James, E.; Jang, D.; Jayatilaka, B.; Jeon, E. J.; Jindariani, S.; Jones, M.; Joo, K. K.; Jun, S. Y.; Junk, T. R.; Kambeitz, M.; Kamon, T.; Karchin, P. E.; Kasmi, A.; Kato, Y.; Ketchum, W.; Keung, J.; Kilminster, B.; Kim, D. H.; Kim, H. S.; Kim, J. E.; Kim, M. J.; Kim, S. H.; Kim, S. B.; Kim, Y. J.; Kim, Y. K.; Kimura, N.; Kirby, M.; Knoepfel, K.; Kondo, K.; Kong, D. J.; Konigsberg, J.; Kotwal, A. V.; Kreps, M.; Kroll, J.; Kruse, M.; Kuhr, T.; Kurata, M.; Laasanen, A. T.; Lammel, S.; Lancaster, M.; Lannon, K.; Latino, G.; Lee, H. S.; Lee, J. S.; Leo, S.; Leone, S.; Lewis, J. D.; Limosani, A.; Lipeles, E.; Lister, A.; Liu, H.; Liu, Q.; Liu, T.; Lockwitz, S.; Loginov, A.; Lucchesi, D.; Lucà, A.; Lueck, J.; Lujan, P.; Lukens, P.; Lungu, G.; Lys, J.; Lysak, R.; Madrak, R.; Maestro, P.; Malik, S.; Manca, G.; Manousakis-Katsikakis, A.; Marchese, L.; Margaroli, F.; Marino, P.; Martínez, M.; Matera, K.; Mattson, M. E.; Mazzacane, A.; Mazzanti, P.; McNulty, R.; Mehta, A.; Mehtala, P.; Mesropian, C.; Miao, T.; Mietlicki, D.; Mitra, A.; Miyake, H.; Moed, S.; Moggi, N.; Moon, C. S.; Moore, R.; Morello, M. J.; Mukherjee, A.; Muller, Th.; Murat, P.; Mussini, M.; Nachtman, J.; Nagai, Y.; Naganoma, J.; Nakano, I.; Napier, A.; Nett, J.; Neu, C.; Nigmanov, T.; Nodulman, L.; Noh, S. Y.; Norniella, O.; Oakes, L.; Oh, S. H.; Oh, Y. D.; Oksuzian, I.; Okusawa, T.; Orava, R.; Ortolan, L.; Pagliarone, C.; Palencia, E.; Palni, P.; Papadimitriou, V.; Parker, W.; Pauletta, G.; Paulini, M.; Paus, C.; Phillips, T. J.; Piacentino, G.; Pianori, E.; Pilot, J.; Pitts, K.; Plager, C.; Pondrom, L.; Poprocki, S.; Potamianos, K.; Pranko, A.; Prokoshin, F.; Ptohos, F.; Punzi, G.; Ranjan, N.; Redondo Fernández, I.; Renton, P.; Rescigno, M.; Rimondi, F.; Ristori, L.; Robson, A.; Rodriguez, T.; Rolli, S.; Ronzani, M.; Roser, R.; Rosner, J. L.; Ruffini, F.; Ruiz, A.; Russ, J.; Rusu, V.; Sakumoto, W. K.; Sakurai, Y.; Santi, L.; Sato, K.; Saveliev, V.; Savoy-Navarro, A.; Schlabach, P.; Schmidt, E. E.; Schwarz, T.; Scodellaro, L.; Scuri, F.; Seidel, S.; Seiya, Y.; Semenov, A.; Sforza, F.; Shalhout, S. Z.; Shears, T.; Shepard, P. F.; Shimojima, M.; Shochet, M.; Shreyber-Tecker, I.; Simonenko, A.; Sliwa, K.; Smith, J. R.; Snider, F. D.; Song, H.; Sorin, V.; St. Denis, R.; Stancari, M.; Stentz, D.; Strologas, J.; Sudo, Y.; Sukhanov, A.; Suslov, I.; Takemasa, K.; Takeuchi, Y.; Tang, J.; Tecchio, M.; Teng, P. K.; Thom, J.; Thomson, E.; Thukral, V.; Toback, D.; Tokar, S.; Tollefson, K.; Tomura, T.; Tonelli, D.; Torre, S.; Torretta, D.; Totaro, P.; Trovato, M.; Ukegawa, F.; Uozumi, S.; Velev, G.; Vellidis, C.; Vernieri, C.; Vidal, M.; Vilar, R.; Vizán, J.; Vogel, M.; Volpi, G.; Vázquez, F.; Wagner, P.; Wallny, R.; Wang, S. M.; Waters, D.; Wester, W. C.; Whiteson, D.; Wicklund, A. B.; Wilbur, S.; Williams, H. H.; Wilson, J. S.; Wilson, P.; Winer, B. L.; Wittich, P.; Wolbers, S.; Wolfe, H.; Wright, T.; Wu, X.; Wu, Z.; Yamamoto, K.; Yamato, D.; Yang, T.; Yang, U. K.; Yang, Y. C.; Yao, W. -M.; Yeh, G. P.; Yi, K.; Yoh, J.; Yorita, K.; Yoshida, T.; Yu, G. B.; Yu, I.; Zanetti, A. M.; Zeng, Y.; Zhou, C.; Zucchelli, S.

    2014-06-09

    The first search for single-top-quark production from the exchange of an s -channel virtual W boson using events with an imbalance in the total transverse energy, b -tagged jets, and no identified leptons is presented. Assuming the electroweak production of top quarks of mass 172.5 GeV / c 2 in the s channel, a cross section of 1.1 2 $+ 0.61\\atop{- 0.57}$ ( stat + syst ) pb with a significance of 1.9 standard deviations is measured. This measurement is combined with the result obtained from events with an imbalance in total transverse momentum, b -tagged jets, and exactly one identified lepton, yielding a cross section of 1.3 6$+ 0.37\\atop{- 0.32}$ ( stat + syst ) pb, with a significance of 4.2 standard deviations.

  6. Apparent and true resistant hypertension: definition, prevalence and outcomes.

    Science.gov (United States)

    Judd, E; Calhoun, D A

    2014-08-01

    Resistant hypertension, defined as blood pressure (BP) remaining above goal despite the use of > or =3 antihypertensive medications at maximally tolerated doses (one ideally being a diuretic) or BP that requires > or =4 agents to achieve control, has received more attention with increased efforts to improve BP control rates and the emergence of device-based therapies for hypertension. This classically defined resistant group consists of patients with true resistant hypertension, controlled resistant hypertension and pseudo-resistant hypertension. In studies where pseudo-resistant hypertension cannot be excluded (for example, 24-h ambulatory BP not obtained), the term apparent resistant hypertension has been used to identify 'apparent' lack of control on > or =3 medications. Large, well-designed studies have recently reported the prevalence of resistant hypertension. Pooling prevalence data from these studies and others within North America and Europe with a combined sample size of >600,000 hypertensive participants, the prevalence of resistant hypertension is 14.8% of treated hypertensive patients and 12.5% of all hypertensives. However, the prevalence of true resistant hypertension, defined as uncontrolled both by office and 24-h ambulatory BP monitoring with confirmed medication adherence, may be more meaningful in terms of identifying risk and estimating benefit from newer therapies like renal denervation. Rates of cardiovascular events and mortality follow mean 24-h ambulatory BPs in patients with resistant hypertension, and true resistant hypertension represents the highest risk. The prevalence of true resistant hypertension has not been directly measured in large trials; however, combined data from smaller studies suggest that true resistant hypertension is present in half of the patients with resistant hypertension who are uncontrolled in the office. Our pooled analysis shows prevalence rates of 10.1% and 7.9% for uncontrolled resistant hypertension among

  7. Neural Global Pattern Similarity Underlies True and False Memories.

    Science.gov (United States)

    Ye, Zhifang; Zhu, Bi; Zhuang, Liping; Lu, Zhonglin; Chen, Chuansheng; Xue, Gui

    2016-06-22

    The neural processes giving rise to human memory strength signals remain poorly understood. Inspired by formal computational models that posit a central role of global matching in memory strength, we tested a novel hypothesis that the strengths of both true and false memories arise from the global similarity of an item's neural activation pattern during retrieval to that of all the studied items during encoding (i.e., the encoding-retrieval neural global pattern similarity [ER-nGPS]). We revealed multiple ER-nGPS signals that carried distinct information and contributed differentially to true and false memories: Whereas the ER-nGPS in the parietal regions reflected semantic similarity and was scaled with the recognition strengths of both true and false memories, ER-nGPS in the visual cortex contributed solely to true memory. Moreover, ER-nGPS differences between the parietal and visual cortices were correlated with frontal monitoring processes. By combining computational and neuroimaging approaches, our results advance a mechanistic understanding of memory strength in recognition. What neural processes give rise to memory strength signals, and lead to our conscious feelings of familiarity? Using fMRI, we found that the memory strength of a given item depends not only on how it was encoded during learning, but also on the similarity of its neural representation with other studied items. The global neural matching signal, mainly in the parietal lobule, could account for the memory strengths of both studied and unstudied items. Interestingly, a different global matching signal, originated from the visual cortex, could distinguish true from false memories. The findings reveal multiple neural mechanisms underlying the memory strengths of events registered in the brain. Copyright © 2016 the authors 0270-6474/16/366792-11$15.00/0.

  8. PLATONISTS AND GNOSTICS ON NEGATIVE THEOLOGY AND TRUE INNER SELF

    Directory of Open Access Journals (Sweden)

    VICTOR ALEXANDRU PRICOPI

    2014-11-01

    Full Text Available Late Antiquity is characterized by a strong search for human’s true nature. This is proper to almost all philosophical and religious movements in the first three Christian centuries. Christians, Gnostics, and philosophers of those days aim to find the true nature of man. In this study we will deal mainly with anthropology and gnoseology of Valentinian Gnostics and Platonists. In their case, knowledge of human nature is inextricably linked to knowledge of God's true nature. These thinkers say that the first Principle/the Father/the source of this universe is inherently unknowable, indescribable and unspeakable. However, God can be known, either through secret revelation (Gnostics or through a purely rational approach (Platonists. For these thinkers, the true knowledge of the Divine Principle and knowledge of the human being or the world we live in is carried out in a double sense. By knowing God is possible the knowledge of human nature, while knowing human nature unfolds the nature of the first Principle. This is due to the fact that although the creator is alien to this world, he is now here through man true nature. In other words, in man there is a spark of the divine that has fallen or was dropped in the sublunary world. These ideas are found in Plato’s Phaedrus, Meno or Phaedo and also in some Valentinian gnostic texts as Gospel of Truth, Tripartite Tractate, Gospel of Philip and Treatise on Resurrection. Therefore, in this paper we will analyze the Platonists conceptions about human nature in comparison to Gnostic conception of man, as it appears in Plato’s works and Coptic texts discovered in Egypt, at Nag Hammadi.

  9. Critical opalescence and the true dielectric state in a Coulomb system

    Science.gov (United States)

    Bobrov, V. B.; Trigger, S. A.

    2015-04-01

    To study the critical opalescence effect in a two-component Coulomb system consisting of single-type electrons and nuclei, we consider the limit relations for static structure factors and analyze the singularities of the dielectric permittivity. We show that the critical opalescence effect can be observed not only at the critical point corresponding to the gas-liquid phase transition but also near the true dielectric state with zero static conductivity. With the available experimental data taken into account, we assume that the true dielectric state is the limit state of the liquid-liquid phase transition accompanied by sharp variations in the electrical conduction of the substances. We find that if the thermodynamic parameters correspond to the true dielectric state, then the critical opalescence effect can arise in the case where the squared fluctuation in the total number of electrons and nuclei in a two-component Coulomb system becomes infinite, as this occurs at the critical point corresponding to the gas-liquid phase transition.

  10. Comparison of true metabolisable energy and true amino acid availability between normal maize and quality protein maize (Shandan 17

    Directory of Open Access Journals (Sweden)

    Mei Li Zhang

    2010-01-01

    Full Text Available A precision-fed assay was conducted to determine true metabolisable energy and true amino acid digestibility in Chinese quality protein maize (QPM compared with normal maize (NM. Thirty adult roosters, kept in individual cages, were made to fast for 48h and then tub-fed 50g QPM or NM per bird and their excreta was colleted for the subsequent 48h. Additional fifteen roosters were made to fast in order to estimate endogenous losses of energy and amino acids (AA in excreta. Gross energy of the two types of maize were similar; the lysine content in NM and QPM were 0.27% and 0.41% (DM basis, respectively. True metabolisable energy (TME and true metabolisable energy nitrogen corrected (TMEn values of QPM and NM were not significantly different (P>0.05. Digestibility of some AA, including lysine and methionine, in QPM were higher than those in NM (P<0.05. The results of this study indicated that the nutritive value of QPM might be higher than that of NM.

  11. True single-molecule DNA sequencing of a pleistocene horse bone

    DEFF Research Database (Denmark)

    Orlando, Ludovic Antoine Alexandre; Ginolhac, Aurélien; Raghavan, Maanasa

    2011-01-01

    -preserved Pleistocene horse bone using the Helicos HeliScope and Illumina GAIIx platforms, respectively. We find that the percentage of endogenous DNA sequences derived from the horse is higher among the Helicos data than Illumina data. This result indicates that the molecular biology tools used to generate sequencing...

  12. Parent artery occlusion for ruptured "true" posterior communicating artery aneurysm.

    Science.gov (United States)

    Mitsuhashi, Takashi; Takeda, Nobuaki; Oishi, Hidenori; Arai, Hajime

    2015-04-01

    A case of a patient with a ruptured true posterior communicating artery (PCoA) aneurysm is reported, who had been managed by early endovascular parent artery occlusion with coils. The small blister aneurysm was located at the proximal PCoA itself and directed superiorly. Postoperative course was uneventful. During 1-month follow-up, the patient recovered well and could care for herself. Aneurysms of the PCoA itself are very rare. As reported to date, surgical procedures would favor microsurgical clipping over endovascular coil embolization. Endovascular treatment may be a good alternative to surgical trapping for true PCoA blister aneurysm. © The Author(s) 2015 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  13. Endovascular treatment of a true posterior communicating artery aneurysm.

    Science.gov (United States)

    Munarriz, Pablo M; Castaño-Leon, Ana M; Cepeda, Santiago; Campollo, Jorge; Alén, Jose F; Lagares, Alfonso

    2014-01-01

    Posterior communicating artery (PCoA) aneurysms are most commonly located at the junction of the internal carotid artery and the PCoA. "True" PCoA aneurysms, which originate from the PCoA itself, are rarely encountered. Most previously reported cases were treated surgically mainly before the endovascular option became available. A 53-year-old male presented with sudden onset of right hemiparesis and aphasia. Left middle cerebral artery stroke was diagnosed. Further studies revealed a 3 mm left PCoA aneurysm arising from the PCoA itself, attached to neither the internal carotid artery nor the posterior cerebral artery. Endovascular treatment was performed and the aneurysm was coiled completely. Technical advances in endovascular interventional technology have permitted an additional approach to these lesions. The possible endovascular significance of the treatment of true PCoA aneurysms is discussed.

  14. Two Cases of True Uterine Artery Aneurysms Diagnosed during Pregnancy

    DEFF Research Database (Denmark)

    Schlütter, Jacob Mørup; Johansen, Gry; Helmig, Rikke Bek

    2016-01-01

    We report 2 cases of true uterine artery aneurysms diagnosed during pregnancy. Both cases presented with nonspecific symptoms such as urethral obstruction, minimal vaginal bleeding and lower abdominal pain in the 2nd trimester. Both aneurysms were diagnosed by color Doppler ultrasound. In the fir...... masses, vague bladder symptoms or radiating pelvic pain. The diagnosis is readily made by color Doppler imaging. Elective Caesarean section should be the preferred mode of delivery to avoid rupture of the aneurysm during labor.......We report 2 cases of true uterine artery aneurysms diagnosed during pregnancy. Both cases presented with nonspecific symptoms such as urethral obstruction, minimal vaginal bleeding and lower abdominal pain in the 2nd trimester. Both aneurysms were diagnosed by color Doppler ultrasound. In the first...

  15. Chernobyl, the true, the false and the uncertain

    International Nuclear Information System (INIS)

    1996-04-01

    This work makes the part between the true and the false information in France about the Chernobyl accident that have been read in different newspapers during the last years. This document is divide in three parts: what is true, what is false, what is uncertain. In each part are noticed extracts from newspapers face to the synthesis of thoughts about them. It is the fourth edition, the first one was in April 1990, the second one was in 1992 after a report from IAEA on the radiological consequences, the third edition was born in 1994 with the emergence of thyroid cancers especially among children, this fourth edition of 1996 takes into account the sanitary report given by the World Health Organisation experts in 1995. It confirms the progression of thyroid cancers and the absence of any other cancer as well leukemia. (N.C.)

  16. Content Adaptive True Motion Estimator for H.264 Video Compression

    Directory of Open Access Journals (Sweden)

    P. Kulla

    2007-12-01

    Full Text Available Content adaptive true motion estimator for H.264 video coding is a fast block-based matching estimator with implemented multi-stage approach to estimate motion fields between two image frames. It considers the theory of 3D scene objects projection into 2D image plane for selection of motion vector candidates from the higher stages. The stages of the algorithm and its hierarchy are defined upon motion estimation reliability measurement (image blocks including two different directions of spatial gradient, blocks with one dominant spatial gradient and blocks including minimal spatial gradient. Parameters of the image classification into stages are set adaptively upon image structure. Due to search strategy are the estimated motion fields more corresponding to a true motion in an image sequence as in the case of conventional motion estimation algorithms that use fixed sets of motion vector candidates from tight neighborhood.

  17. Electrically tunable photonic true-time-delay line.

    Science.gov (United States)

    Barmenkov, Yuri O; Cruz, José Luis; Díez, Antonio; Andrés, Miguel V

    2010-08-16

    We present a new application of the acousto-optic superlattice modulation of a fiber Bragg grating based on the dynamic phase and group delay properties of this fiber-optic component. We demonstrate a tunable photonic true-time-delay line based on the group delay change of the light reflected from the grating sidebands. The delay is electrically tuned by adjusting the voltage applied to a piezoelectric transducer that generates the acoustic wave propagating along the grating. In our experiments, a true-time delay of 400 ps is continuously adjusted (300 ps within the 3 dB amplitude range of the first sideband), using a 12 cm long uniform grating.

  18. An Explanation of True Dreams: Aristotle and Jung

    Directory of Open Access Journals (Sweden)

    Ali Sanai

    2016-12-01

    Full Text Available The naturalistic explanation of realized dream (or dreams that come true means that this phenomen will be explained regardless of supernatural agents. Aristotle in Parva naturalia and Jung in his works explained dream visionary. In this article by scrutiny on these thinkers’ theory, we will indicate the naturalistic approach to dream that is far- fetched for followers of metaphysics. In spite of this fact that Aristotle and Jung both belongs to different historical contexts, they have common aspects in terms of naturalistic method; in the universal or broad sense of word, but in terms of content both explain the true dream by the term “coincidence” or accidental conformity between objective events and psychological affairs. It also seems that the notion of Neutral monism in Jung is adaptive to Hylomorphism in Aristotle psychology, and this, provides a path for naturalistic approach to dream as one forms of consciousness.

  19. ID-Check: Online Concealed Information Test Reveals True Identity.

    Science.gov (United States)

    Verschuere, Bruno; Kleinberg, Bennett

    2016-01-01

    The Internet has already changed people's lives considerably and is likely to drastically change forensic research. We developed a web-based test to reveal concealed autobiographical information. Initial studies identified a number of conditions that affect diagnostic efficiency. By combining these moderators, this study investigated the full potential of the online ID-check. Participants (n = 101) tried to hide their identity and claimed a false identity in a reaction time-based Concealed Information Test. Half of the participants were presented with personal details (e.g., first name, last name, birthday), whereas the others only saw irrelevant details. Results showed that participants' true identity could be detected with high accuracy (AUC = 0.98; overall accuracy: 86-94%). Online memory detection can reliably and validly detect whether someone is hiding their true identity. This suggests that online memory detection might become a valuable tool for forensic applications. © 2015 American Academy of Forensic Sciences.

  20. Commercialized VCSEL components fabricated at TrueLight Corporation

    Science.gov (United States)

    Pan, Jin-Shan; Lin, Yung-Sen; Li, Chao-Fang A.; Chang, C. H.; Wu, Jack; Lee, Bor-Lin; Chuang, Y. H.; Tu, S. L.; Wu, Calvin; Huang, Kai-Feng

    2001-05-01

    TrueLight Corporation was found in 1997 and it is the pioneer of VCSEL components supplier in Taiwan. We specialize in the production and distribution of VCSEL (Vertical Cavity Surface Emitting Laser) and other high-speed PIN-detector devices and components. Our core technology is developed to meet blooming demand of fiber optic transmission. Our intention is to diverse the device application into data communication, telecommunication and industrial markets. One mission is to provide the high performance, highly reliable and low-cost VCSEL components for data communication and sensing applications. For the past three years, TrueLight Corporation has entered successfully into the Gigabit Ethernet and the Fiber Channel data communication area. In this paper, we will focus on the fabrication of VCSEL components. We will present you the evolution of implanted and oxide-confined VCSEL process, device characterization, also performance in Gigabit data communication and the most important reliability issue

  1. Endovascular treatment of a true posterior communicating artery aneurysm

    OpenAIRE

    Munarriz, Pablo M.; Castaño-Leon, Ana M.; Cepeda, Santiago; Campollo, Jorge; Alén, Jose F.; Lagares, Alfonso

    2014-01-01

    Background: Posterior communicating artery (PCoA) aneurysms are most commonly located at the junction of the internal carotid artery and the PCoA. "True" PCoA aneurysms, which originate from the PCoA itself, are rarely encountered. Most previously reported cases were treated surgically mainly before the endovascular option became available. Case Description: A 53-year-old male presented with sudden onset of right hemiparesis and aphasia. Left middle cerebral artery stroke was diagnosed. F...

  2. Apparent and true resistant hypertension: definition, prevalence and outcomes

    OpenAIRE

    Judd, E; Calhoun, DA

    2014-01-01

    Resistant hypertension, defined as blood pressure (BP) remaining above goal despite the use of ≥3 antihypertensive medications at maximally tolerated doses (one ideally being a diuretic) or BP that requires ≥4 agents to achieve control, has received more attention with increased efforts to improve BP control rates and the emergence of device-based therapies for hypertension. This classically defined resistant group consists of patients with true resistant hypertension, controlled resistant hy...

  3. True ownership of traditional medicines in South Africa

    OpenAIRE

    Gabriel Louw; André Duvenhage

    2017-01-01

    Background Literature postulates that traditional medicines form an important part of modern-day South African healthcare. The belief is that the traditional healer and traditional medicine is a close-knit unit, with the traditional healer as the true owner and manufacturer of traditional medicines. Various studies also postulate that the growth and development of South African traditional medicines are restricted by the pharmaceutical industries and other role players...

  4. True many-particle scattering theory in oscillator representation

    International Nuclear Information System (INIS)

    Smirnov, Yu.F.; Shirokov, A.M.

    1988-01-01

    The scattering theory in oscillator representation in case of true multiparticle scattering (TMS) is generalized. All necessary expressions to construct a wave function of several particles system in a discrete or continuous spectra at TMS approximation are obtained. Essential advantage of the method suggested lies in the fact that the most difficult part: construction and diagonolization of the Hamiltonian cutted matrix is to be carried out only once, and then the wave function can be calculated at any designed energy. 23 refs

  5. True Crime: Forbrydelse, fortælling og dom

    DEFF Research Database (Denmark)

    Lundtofte, Thomas Enemark

    2016-01-01

    De seneste år har budt på en række opsigtsvækkende dokumentarkrimiserier, der har udfordret det amerikanske retssystem. Serierne inviterer os til at tage stilling til skyldsspørgsmål og blande os i debatten om retfærdighed. Angiveligt som følge af true crime-serien Making a Murderer (2015) bliver...

  6. Psychotherapy of the child with true brain damage.

    Science.gov (United States)

    Christ, Adolph E

    1978-07-01

    Psychotherapy of the child with true brain damage presents special problems and requires special approaches. Those who are cognitively primitive--at the sensorimotor or preoperational stage of development--require a crisis approach; those at the concrete or formal operational stage can be treated with a modified insight-oriented approach. Development of a therapeutic alliance, establishment of workable defense mechanisms, identification and clarification of unalterable cognitive defects and issues of termination unique to this special population are discussed.

  7. A material-sparing method for simultaneous determination of true density and powder compaction properties--aspartame as an example.

    Science.gov (United States)

    Sun, Changquan Calvin

    2006-12-01

    True density results for a batch of commercial aspartame are highly variable when helium pycnometry is used. Alternatively, the true density of the problematic aspartame lot was obtained by fitting tablet density versus pressure data. The fitted true density was in excellent agreement with that predicted from single crystal structure. Tablet porosity was calculated from the true density and tablet apparent density. After making the necessary measurements for calculating tablet apparent density, the breaking force of each intact tablet was measured and tensile strength was calculated. With the knowledge of compaction pressure, tablet porosity and tensile strength, powder compaction properties were characterized using tabletability (tensile strength versus pressure), compactibility (tensile strength versus porosity), compressibility (porosity versus pressure) and Heckel analysis. Thus, a wealth of additional information on the compaction properties of the powder was obtained through little added work. A total of approximately 4 g of powder was used in this study. Depending on the size of tablet tooling, tablet thickness and true density, 2-10 g of powder would be sufficient for characterizing most pharmaceutical powders.

  8. True or Not True.

    Science.gov (United States)

    Fields, Joyce I.

    1993-01-01

    Ascertained seven- and eight-year-olds' understanding of advertising, the role of the buyer and seller, and the role of real estate agents. Interviewed an experimental group of students who had been exposed, and a control group of students who had not been exposed, to classroom presentations concerning these topics. (MDM)

  9. The True Ultracool Binary Fraction Using Spectral Binaries

    Science.gov (United States)

    Bardalez Gagliuffi, Daniella; Burgasser, Adam J.; Schmidt, Sarah J.; Gagné, Jonathan; Faherty, Jacqueline K.; Cruz, Kelle; Gelino, Chris

    2018-01-01

    Brown dwarfs bridge the gap between stars and giant planets. While the essential mechanisms governing their formation are not well constrained, binary statistics are a direct outcome of the formation process, and thus provide a means to test formation theories. Observational constraints on the brown dwarf binary fraction place it at 10 ‑ 20%, dominated by imaging studies (85% of systems) with the most common separation at 4 AU. This coincides with the resolution limit of state-of-the-art imaging techniques, suggesting that the binary fraction is underestimated. We have developed a separation-independent method to identify and characterize tightly-separated (dwarfs as spectral binaries by identifying traces of methane in the spectra of late-M and early-L dwarfs. Imaging follow-up of 17 spectral binaries yielded 3 (18%) resolved systems, corroborating the observed binary fraction, but 5 (29%) known binaries were missed, reinforcing the hypothesis that the short-separation systems are undercounted. In order to find the true binary fraction of brown dwarfs, we have compiled a volume-limited, spectroscopic sample of M7-L5 dwarfs and searched for T dwarf companions. In the 25 pc volume, 4 candidates were found, three of which are already confirmed, leading to a spectral binary fraction of 0.95 ± 0.50%, albeit for a specific combination of spectral types. To extract the true binary fraction and determine the biases of the spectral binary method, we have produced a binary population simulation based on different assumptions of the mass function, age distribution, evolutionary models and mass ratio distribution. Applying the correction fraction resulting from this method to the observed spectral binary fraction yields a true binary fraction of 27 ± 4%, which is roughly within 1σ of the binary fraction obtained from high resolution imaging studies, radial velocity and astrometric monitoring. This method can be extended to identify giant planet companions to young brown

  10. True aneurysm of the proximal occipital artery: Case report.

    Science.gov (United States)

    Illuminati, Giulio; Cannistrà, Marco; Pizzardi, Giulia; Pasqua, Rocco; Frezzotti, Francesca; Calio', Francesco G

    2018-01-01

    True aneurysms of the proximal occipital artery are rare, may cause neurological symptoms due to compression of the hypoglossal nerve and their resection may be technically demanding. The case of an aneurysm of the proximal occipital artery causing discomfort and tongue deviation by compression on the hypoglossal nerve is reported. Postoperative course after resection was followed by complete regression of symptoms. Surgical resection, as standard treatment of aneurysms of the occipital artery, with the eventual technical adjunct of intubation by the nose is effective in durably relieving symptoms and preventing aneurysm-related complication. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

  11. True aneurysm of the proximal occipital artery: Case report

    Directory of Open Access Journals (Sweden)

    Giulio Illuminati

    Full Text Available Introduction: True aneurysms of the proximal occipital artery are rare, may cause neurological symptoms due to compression of the hypoglossal nerve and their resection may be technically demanding. Presentation of case: The case of an aneurysm of the proximal occipital artery causing discomfort and tongue deviation by compression on the hypoglossal nerve is reported. Postoperative course after resection was followed by complete regression of symptoms. Conclusion: Surgical resection, as standard treatment of aneurysms of the occipital artery, with the eventual technical adjunct of intubation by the nose is effective in durably relieving symptoms and preventing aneurysm-related complication. Keywords: Arterial aneurysm, Occipital artery, Case report

  12. The true invariant of an arbitrage free portfolio

    Science.gov (United States)

    Schmidt, Anatoly B.

    2003-03-01

    It is shown that the arbitrage free portfolio paradigm being applied to a portfolio with an arbitrary number of shares N allows for the extended solution in which the option price F depends on N. However the resulting stock hedging expense Q= MF (where M is the number of options in the portfolio) does not depend on whether N is treated as an independent variable or as a parameter. Therefore the stock hedging expense is the true invariant of the arbitrage free portfolio paradigm.

  13. True versus spurious state dependence in firm performance

    DEFF Research Database (Denmark)

    Kaiser, Ulrich; Kongsted, Hans Christian

    2008-01-01

    This paper analyzes the persistence of firms' exporting behavior in a panel of German manufacturing firms using dynamic binary choice models. We distinguish between true and spurious state dependence in exports and apply fixed effects methods that allow us to verify the robustness of our results ...... determinants. Our results, which are consistent with the findings of previous studies on firms in developing countries and in the United States, show the presence of important sunk costs in export market entry and a depreciation of knowledge and experience in export markets....

  14. True Versus Spurious State Dependence in Firm Performance

    DEFF Research Database (Denmark)

    Kaiser, Ulrich; Kongsted, Hans Christian

    This paper analyzes the persistence of firms' exporting behavior in a panel of German manufacturing firms using dynamic binary choice models. We distinguish between true and spurious state dependence in exports and apply fixed effects methods that allow us to verify the robustness of our results ...... determinants. Our results, which are consistent with the findings of previous studies on firms in developing countries and in the United States, show the presence of important sunk costs in export market entry and a depreciation of knowledge and experience in export markets...

  15. Arendt on Hobbes as the true philosopher of the bourgeoisie

    Directory of Open Access Journals (Sweden)

    Adriano Correia

    2015-07-01

    Full Text Available In The Origins of Totalitarianism, when examine the elements and origins of total domination, Hannah Arendt devotes special attention to the political emancipation of the bourgeoisie. For Arendt imperialism is the truth of the bourgeois understanding of politics, according to which politics should not be more than a well-organized police force. The truth of bourgeois politics is the reduction of politics to mere force. Our purpose is to reconstruct this movement from the vantage point of arendtian appropriation of Hobbes, "the true philosopher of the bourgeoisie."

  16. Correction of the post -- necking true stress -- strain data using instrumented nanoindentation

    Science.gov (United States)

    Romero Fonseca, Ivan Dario

    strains were 0.028, 0.062 and 0.061 for G101800, C11000 and S30400 respectively. The established corrected curves relating post-necking flow stress to true plastic strain turned out to be well represented by a power-law function. Experimental results dictated that a unique single value for C and for epsilonr is not appropriate to describe materials with different plastic behaviors. Therefore, Tabor's equation, along with the representative plastic strain concept, has been misused in the past. The studied materials exhibited different nanohardness and plastic strain distributions due to their inherently distinct elasto-plastic response. The proposed post-necking correction separates out the effect of triaxiality on the uniaxial true stress-strain curve provided that the nanohardness-flow stress relationship is based on uniaxial values of stress. Some type of size effect, due to the microvoids at the tip of the neck, influenced nanohardness measurements. The instrumented nanoindentation technique proved to be a very suitable method to probe elasto-plastic properties of materials such as nanohardness, elastic modulus, and quasi-static strain rate sensitivity among others. Care should be taken when converting nanohardness to Vickers and vice versa due to their different area definition used. Nanohardness to Vickers ratio oscillated between 1.01 and 1.17.

  17. A Screening Mechanism Differentiating True from False Pain during Empathy.

    Science.gov (United States)

    Sun, Ya-Bin; Lin, Xiao-Xiao; Ye, Wen; Wang, Ning; Wang, Jin-Yan; Luo, Fei

    2017-09-13

    Empathizing with another's suffering is important in social interactions. Empathic behavior is selectively elicited from genuine, meaningful pain but not from fake, meaningless scenarios. However, the brain's screening mechanism of false information from meaningful events and the time course for the screening process remains unclear. Using EEG combined with principle components analysis (PCA) techniques, here we compared temporal neurodynamics between the observation of pain and no-pain pictures as well as between true (painful expressions and needle-penetrated arms) and false (needle-penetrated faces with neutral expressions) pain pictures. The results revealed that pain vs. no-pain information is differentiated in the very early ERP components, i.e., the N1/P1 for the face and arm pictures categories and the VPP/N170 for the facial expression category while the mid-latency ERP components, N2 and P3, played key roles in differentiating true from false situations. The complex of N2 and P3 components may serve as a screening mechanism through which observers allocate their attentions to more important or relevant events and screen out false environmental information. This is the first study to describe and provide a time course of the screening process during pain empathy. These findings shed new light on the understanding of empathic processing.

  18. Magnetic Resonance Imaging Study Using True versus Sham Acupuncture

    Directory of Open Access Journals (Sweden)

    Chunxiao Wu

    2014-01-01

    Full Text Available Functional magnetic resonance imaging (fMRI has been shown to detect the specificity of acupuncture points, as proved by numerous studies. In this study, resting-state fMRI was used to observe brain areas activated by acupuncture at the Taichong (LR3 acupoint. A total of 15 healthy subjects received brain resting-state fMRI before acupuncture and after sham and true acupuncture, respectively, at LR3. Image data processing was performed using Data Processing Assistant for Resting-State fMRI and REST software. The combination of amplitude of low-frequency fluctuation (ALFF and regional homogeneity (ReHo was used to analyze the changes in brain function during sham and true acupuncture. Acupuncture at LR3 can specifically activate or deactivate brain areas related to vision, movement, sensation, emotion, and analgesia. The specific alterations in the anterior cingulate gyrus, thalamus, and cerebellar posterior lobe have a crucial effect and provide a valuable reference. Sham acupuncture has a certain effect on psychological processes and does not affect brain areas related to function.

  19. [Intel random number generator-based true random number generator].

    Science.gov (United States)

    Huang, Feng; Shen, Hong

    2004-09-01

    To establish a true random number generator on the basis of certain Intel chips. The random numbers were acquired by programming using Microsoft Visual C++ 6.0 via register reading from the random number generator (RNG) unit of an Intel 815 chipset-based computer with Intel Security Driver (ISD). We tested the generator with 500 random numbers in NIST FIPS 140-1 and X(2) R-Squared test, and the result showed that the random number it generated satisfied the demand of independence and uniform distribution. We also compared the random numbers generated by Intel RNG-based true random number generator and those from the random number table statistically, by using the same amount of 7500 random numbers in the same value domain, which showed that the SD, SE and CV of Intel RNG-based random number generator were less than those of the random number table. The result of u test of two CVs revealed no significant difference between the two methods. Intel RNG-based random number generator can produce high-quality random numbers with good independence and uniform distribution, and solves some problems with random number table in acquisition of the random numbers.

  20. Optical resonators for true-time-delay beam steering

    Science.gov (United States)

    Gesell, Leslie H.; Evanko, Stephen M.

    1996-06-01

    Conventional true time delay beamforming and steering devices rely on switching between various lengths of delay line. Therefore only discrete delays are possible. Proposed is a new photonics concept for true time delay beamforming which provides a finely controlled continuum of delays with switching speeds on the order of 10's of nanoseconds or faster. The architecture uses an array of waveguide cavities with different resonate frequencies to channelize the signal. Each spectral component of the signal is phase shifted by an amount proportional to the frequency of that component and the desired time delay. These phase shifted spectral components are then summed to obtain the delayed signal. This paper provides an overview of the results of a Phase I SBIR contract where this concept has been refined and analyzed. The parameters for an operational system are determined and indication of the feasibility of this approach is given. Among the issues addressed are the requirements of the resonators and the methods necessary to implement fiber optic Bragg gratings as these resonators.

  1. Perfusion MR imaging of the heart with TrueFISP

    International Nuclear Information System (INIS)

    Schreiber, W.G.; Schmitt, M.; Kalden, P.; Mohrs, O.; Kreitner, K.F.; Thelen, M.; Horstick, G.; Gumbrich, T.; Petersen, S.; Voigtlaender, T.

    2001-01-01

    Objective: Development and test of a saturation-recovery TrueFISP (SR-Trufi) pulse sequence for myocardial perfusion MR imaging (MRI) using improved gradient hardware. Material and methods: Measurements were performed on a 1.5 T scanner with prototype gradients (50 mT/m, minimum rise time 300 μs). T 1 -weighted first-pass MRI of Gd-DTPA (0.025 μmol/kg) kinetics in the myocardium was performed using an SR-Trufi pulse sequence (T R /T E /α=2.6 ms/1.4 ms/55 ) with a saturation preparation of TD-30 ms before the TrueFISP readout. Measurements were performed in volunteers (n=4) and in a pig model of chronic ischemia (n=1). Results: In phantoms, the signal intensity was linear with contrast concentration up to 0.9 mmol/kg Gd-DTPA. MR images obtained with SR-Trufi had a good image quality and high spatial resolution of 2.1 mmx2.1 mm. Differences of the contrast agent's kinetics between a subendocardial perfusion deficit and neighboring myocardium were well visible on both MR images and signal-time curves derived from the region-of-interest analysis. Conclusion: SR-Trufi appears to be an interesting new technique for the assessment of myocardial microcirculation using dedicated cardiovascular MR systems. (orig.) [de

  2. Deep Brain Stimulation, Continuity over Time, and the True Self.

    Science.gov (United States)

    Nyholm, Sven; O'Neill, Elizabeth

    2016-10-01

    One of the topics that often comes up in ethical discussions of deep brain stimulation (DBS) is the question of what impact DBS has, or might have, on the patient's self. This is often understood as a question of whether DBS poses a threat to personal identity, which is typically understood as having to do with psychological and/or narrative continuity over time. In this article, we argue that the discussion of whether DBS is a threat to continuity over time is too narrow. There are other questions concerning DBS and the self that are overlooked in discussions exclusively focusing on psychological and/or narrative continuity. For example, it is also important to investigate whether DBS might sometimes have a positive (e.g., a rehabilitating) effect on the patient's self. To widen the discussion of DBS, so as to make it encompass a broader range of considerations that bear on DBS's impact on the self, we identify six features of the commonly used concept of a person's "true self." We apply these six features to the relation between DBS and the self. And we end with a brief discussion of the role DBS might play in treating otherwise treatment-refractory anorexia nervosa. This further highlights the importance of discussing both continuity over time and the notion of the true self.

  3. Final report of the TRUE Block Scale project. 2. Tracer tests in the block scale

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Peter; Byegaard, Johan [Geosigma AB, Uppsala (Sweden); Winberg, Anders [Conterra AB, Partille (Sweden)

    2002-05-01

    retardation noted in the injection. The evaluated K{sub a} values were found to be of a magnitude equitable to the TRUE- 1 laboratory K{sub a} values. Effects of matrix diffusion, sorption kinetics model, non-linear sorption were also explored. The evaluation and interpretation of the block scale tracer breakthrough curves indicated response of a heterogeneous system, observed both from tests in single structures and in network of structures. Results from the deterministic Structure 20 were found to show a signature of a narrow and high-conductive single structure, whereas results from Structure 21 indicated that it is probably more complex than assumed at the onset of the investigation, probably made up of several sub-parallel structures, rather than a single fracture. The network flow paths generally have less steep tails (t{sup -4/2} - t{sup -3/2}) in log-log space than the single structure flow paths. The observed order of retention among the different species was found to be the same as in TRUE-1 and in the laboratory tests, i.e. Na{sup +}TRUE-1 data to the results of 17 m single structure flow paths (C1 and C4) in Structure 20. However, for the breakthroughs of sorbing tracers in the more complex flow paths C3 (Na{sup +}) and C2(Ca{sup 2+}) a 30-80% stronger retardation (expressed as R{sub 50%}) was noted. The reasons for this somewhat enhanced retardation between the two slower and more complicated flow paths (C2 and C3) and the single structure flow paths (C 1 and C4) may be several; e.g. presence of gouge material (fine-grained fault gouge) in the structures, presence of gouge material in fracture intersection zones, differences in the mineralogy along the flow

  4. Final report of the TRUE Block Scale project. 2. Tracer tests in the block scale

    International Nuclear Information System (INIS)

    Andersson, Peter; Byegaard, Johan; Winberg, Anders

    2002-05-01

    . The evaluated K a values were found to be of a magnitude equitable to the TRUE- 1 laboratory K a values. Effects of matrix diffusion, sorption kinetics model, non-linear sorption were also explored. The evaluation and interpretation of the block scale tracer breakthrough curves indicated response of a heterogeneous system, observed both from tests in single structures and in network of structures. Results from the deterministic Structure 20 were found to show a signature of a narrow and high-conductive single structure, whereas results from Structure 21 indicated that it is probably more complex than assumed at the onset of the investigation, probably made up of several sub-parallel structures, rather than a single fracture. The network flow paths generally have less steep tails (t -4/2 - t -3/2 ) in log-log space than the single structure flow paths. The observed order of retention among the different species was found to be the same as in TRUE-1 and in the laboratory tests, i.e. Na + 2≅ Sr 2+ 2+ ≅Rb + + . Another similarity was tha the retardation, expressed as the ratio of the time at which 50% of the sorbing tracer was recovered compared to the conservative tracer (R 50% ), was about the same for most species when comparing TRUE-1 data to the results of 17 m single structure flow paths (C1 and C4) in Structure 20. However, for the breakthroughs of sorbing tracers in the more complex flow paths C3 (Na + ) and C2(Ca 2+ ) a 30-80% stronger retardation (expressed as R 50% ) was noted. The reasons for this somewhat enhanced retardation between the two slower and more complicated flow paths (C2 and C3) and the single structure flow paths (C 1 and C4) may be several; e.g. presence of gouge material (fine-grained fault gouge) in the structures, presence of gouge material in fracture intersection zones, differences in the mineralogy along the flow paths, larger portions of stagnant water to interact with along the flow path, higher porosity in the fracture rim zone

  5. True Local Recurrence Rate in the Conserved Breast After Magnetic Resonance Imaging-Targeted Radiotherapy

    International Nuclear Information System (INIS)

    Whipp, Elisabeth; Beresford, Mark; Sawyer, Elinor; Halliwell, Michael

    2010-01-01

    Purpose: Better accuracy of local radiotherapy may substantially improve local control and thus long-term breast cancer survival. Magnetic resonance imaging (MRI) has high resolution and sensitivity in breast tissue and may depict the tumor bed more accurately than conventional planning techniques. A postoperative complex (POCx) comprises all visible changes thought to be related to surgery within the breast and acts as a surrogate for the tumor bed. This study reports on local recurrence rates after MRI-assisted radiotherapy planning to ensure adequate coverage of the POCx. Methods and Materials: Simple opposed tangential fields were defined by surface anatomy in the conventional manner in 221 consecutive patients. After MRI, fields were modified by a single radiation oncologist to ensure encompassment of the POCx with a 10-mm margin. Genetic analysis was performed on all local relapses (LRs) to distinguish true recurrences (TRs) from new primaries (NPs). Results: This was a high risk cohort at 5 years: only 9.5% were classified as low risk (St Gallen): 43.4% were Grade 3 and 19.9% had surgical margins <1 mm; 62.4% of patients received boosts. Adjustments of standard field margins were required in 69%. After a median follow-up of 5 years, there were 3 LRs (1.3%) as the site of first relapse in 221 patients, comprising two TRs (0.9%) and one NP (0.4%). Conclusions: Accurate targeting of the true tumor bed is critical. MRI may better define the tumor bed.

  6. Estimating the true energy value of a wind farm

    International Nuclear Information System (INIS)

    Bass, J.

    1995-01-01

    To assess the true energy yield of a wind farm taking into account real-world effects such as control losses in individual turbines, losses in the distribution network and wake and topographic effects, this report from the Energy Technology Support Unit, has developed a more appropriate methodology for making economic assessments of wind farm projects. Simulations of wind turbines are used to enable control losses to be quantified, and long term performance data from wind turbines in operational United Kingdom wind farms adds to the accuracy of assessment. A model has also been used to estimate performance of a power distribution system for a wind farm, to enable losses associated with wind turbine, wind speed and various distribution layouts to be predicted. Data on wake effects are drawn from a separate study. All these are drawn into an economic simulation model which predicts a wind farm's likely achievement of its target energy yield, thus demonstrating the risk factors involved. (UK)

  7. Spontaneous resolution of hemorrhagic polyps of the true vocal fold.

    Science.gov (United States)

    Klein, Adam M; Lehmann, Marcus; Hapner, Edie R; Johns, Michael M

    2009-01-01

    Hemorrhagic polyps are the most common benign lesions surgically removed from the vocal folds. Although this modality does offer satisfactory results in most of the cases, there is a subset of polyps that seems to resolve with conservative therapy. This study was performed to examine this subset of polyps. Thirty-four consecutive subjects diagnosed with hemorrhagic polyps of the true vocal fold were retrospectively reviewed to determine the incidence of spontaneous resolution of the lesions with nonsurgical therapy. Sixteen subjects began conservative therapy, consisting of voice therapy and proper vocal hygiene, often while awaiting an optimal personal time for surgical intervention. Of these subjects, nine (56.3%) experienced a resolution of their lesion and symptoms without undergoing surgical therapy. Surgical removal of hemorrhagic polyps is often considered the standard of treatment for these benign lesions. However, these observations support a regimen of voice therapy and observation in select cases.

  8. Evaluation Method of Collision Risk by Using True Motion

    Directory of Open Access Journals (Sweden)

    Hayama Imazu

    2017-03-01

    Full Text Available It is necessary to develop a useful application to use big data like as AIS for safety and efficiency of ship operation. AIS is very useful system to collect targets information, but this information is not effective use yet. The evaluation method of collision risk is one of the cause disturb. Usually the collision risk of ship is evaluated by the value of the Closest Point of Approach (CPA which is related to a relative motion. So, it becomes difficult to find out a safety pass in a congested water. Here, Line of Predicted Collision (LOPC and Obstacle Zone by Target (OZT for evaluation of collision risk are introduced, these values are related to a true motion and it became visible of dangerous place, so it will make easy to find out a safety pass in a congested water.

  9. Lunar true polar wander inferred from polar hydrogen.

    Science.gov (United States)

    Siegler, M A; Miller, R S; Keane, J T; Laneuville, M; Paige, D A; Matsuyama, I; Lawrence, D J; Crotts, A; Poston, M J

    2016-03-24

    The earliest dynamic and thermal history of the Moon is not well understood. The hydrogen content of deposits near the lunar poles may yield insight into this history, because these deposits (which are probably composed of water ice) survive only if they remain in permanent shadow. If the orientation of the Moon has changed, then the locations of the shadowed regions will also have changed. The polar hydrogen deposits have been mapped by orbiting neutron spectrometers, and their observed spatial distribution does not match the expected distribution of water ice inferred from present-day lunar temperatures. This finding is in contrast to the distribution of volatiles observed in similar thermal environments at Mercury's poles. Here we show that polar hydrogen preserves evidence that the spin axis of the Moon has shifted: the hydrogen deposits are antipodal and displaced equally from each pole along opposite longitudes. From the direction and magnitude of the inferred reorientation, and from analysis of the moments of inertia of the Moon, we hypothesize that this change in the spin axis, known as true polar wander, was caused by a low-density thermal anomaly beneath the Procellarum region. Radiogenic heating within this region resulted in the bulk of lunar mare volcanism and altered the density structure of the Moon, changing its moments of inertia. This resulted in true polar wander consistent with the observed remnant polar hydrogen. This thermal anomaly still exists and, in part, controls the current orientation of the Moon. The Procellarum region was most geologically active early in lunar history, which implies that polar wander initiated billions of years ago and that a large portion of the measured polar hydrogen is ancient, recording early delivery of water to the inner Solar System. Our hypothesis provides an explanation for the antipodal distribution of lunar polar hydrogen, and connects polar volatiles to the geologic and geophysical evolution of the Moon

  10. The True Ponte Osteotomy: By the One Who Developed It.

    Science.gov (United States)

    Ponte, Alberto; Orlando, Giuseppe; Siccardi, Gian Luigi

    2018-01-01

    Technique and applications. To define the anatomy, biomechanics, indications, and surgical technique of the true Ponte osteotomy. The Ponte osteotomy, originally developed for thoracic kyphosis, was the first one to obtain posterior shortening of the thoracic spine, maintaining the anterior column load-sharing capacity. It has become a widely applied technique in various types of spine deformities and a frequent topic of presentations at meetings and in scientific articles. Several of them offer unquestionable evidence of an incorrect execution, with consequently distorted outcomes and erroneous conclusions. A clearing up became essential. Our original experience is based on a series of 240 patients with thoracic hyperkyphosis operated in the years 1969-2015, at first with a standard posterior Harrington technique and then by using the Ponte osteotomy with different instrumentations. A series of 78 of them, operated in the years 1987-1997, who had Ponte osteotomies at every level, is presented. The average preoperative kyphosis has been corrected from 80° (range 61°-102°) to 31° (range 15°-50°) by a substantial posterior shortening. A number of publications use the term Ponte osteotomy loosely for by far incomplete resections and mixing it up with Smith-Petersen's osteotomy. The true Ponte osteotomy is capable of producing marked flexibility in extension, flexion and rotation, justifying its wide use in thoracic deformities, mainly in scoliosis. An exact performance of the osteotomy with adequate bony resections, including the laminae, is an absolute condition to take full advantage of its properties. Level IV, therapeutic study. Copyright © 2017 Scoliosis Research Society. Published by Elsevier Inc. All rights reserved.

  11. [A study on the true nature of "Chinese jinseng"].

    Science.gov (United States)

    Yang, Jeong-pil; Yeo, In-sok

    2003-12-01

    Studies generally, it is believed that the ancient 'Chinese ginseng' did exist due to the fact that it is clearly recorded in the Chinese historical and medicine-related sources. Although it is hard to deny that such 'ginseng' did exist in ancient China, the re-examination of its true nature is also necessary. In other words, certain refutation can be made against the claim that ancient 'Chinese jinseng' was in fact 'Panax jinseng' (C. A. Mey.), since the Chinese jinseng accounts do not tell that it is such. For example, when looking into its shape based on descriptions, the 'Chinese Jinseng' has black seed, hairy stem, and violet flower. ' Panax jinseng' on the other hand, has opal seed, no-hair stem, and light-green flower. In terms of cultivation centre, most of mainland China is unsuitable for Jinseng production with the exception of the Shangdang area of Shanxi province, which solely had the reputation of being the production centre of ancient 'Chinese jinseng'. However, when looking into the Chinese sources for jinseng-producing areas, they show that Hepei and Liaoning province and Jiangnan (south of the Yangtze river) areas also have had some jinseng-related history. Regardless of such instance, these regions did not cultivate Panax jinseng. As shown above, ancient 'Chinese jinseng' was far from being identical, in respect to its shape or production areas, to Panax jinseng. Hence, this study came to the conclusion that there is indeed very high skepticism about whether the true nature of 'jinseng' in ancient China was in fact Panax jinseng. On the contrary, there is higher possibility that the ancient 'Chinese jinseng' is totally different plant from Panax jinseng which is actually Codonopsis pilosula. When examining the shape and production areas of Codonopsis pilosula, it is closely matched with many parts of ancient 'Chinese jinseng' texts. In short, it is presumed that the 'Chinese jinseng' did indeed exist in ancient China but it was Codonopsis pilosula

  12. Uniaxial tension test on Rubber at constant true strain rate

    Directory of Open Access Journals (Sweden)

    Sourne H.L.

    2012-08-01

    Full Text Available Elastomers are widely used for damping parts in different industrial contexts because of their remarkable dissipation properties. Indeed, they can undergo severe mechanical loading conditions, i.e., high strain rates and large strains. Nevertheless, the mechanical response of these materials can vary from purely rubber-like to glassy depending on the strain rate undergone. Classically, uniaxial tension tests are made in order to find a relation between the stress and the strain in the material at various strain rates. However, even if the strain rate is searched to be constant, it is the nominal strain rate that is considered. Here we develop a test at constant true strain rate, i.e. the strain rate that is experienced by the material. In order to do such a test, the displacement imposed by the machine is an exponential function of time. This test has been performed with a high speed hydraulic machine for strain rates between 0.01/s and 100/s. A specific specimen has been designed, yielding a uniform strain field (and so a uniform stress field. Furthermore, an instrumented aluminum bar has been used to take into account dynamic effects in the measurement of the applied force. A high speed camera enables the determination of strain in the sample using point tracking technique. Using this method, the stress-strain curve of a rubber-like material during a loading-unloading cycle has been determined, up to a stretch ratio λ = 2.5. The influence of the true strain rate both on stiffness and on dissipation of the material is then discussed.

  13. Tunable Optical True-Time Delay Devices Would Exploit EIT

    Science.gov (United States)

    Kulikov, Igor; DiDomenico, Leo; Lee, Hwang

    2004-01-01

    Tunable optical true-time delay devices that would exploit electromagnetically induced transparency (EIT) have been proposed. Relative to prior true-time delay devices (for example, devices based on ferroelectric and ferromagnetic materials) and electronically controlled phase shifters, the proposed devices would offer much greater bandwidths. In a typical envisioned application, an optical pulse would be modulated with an ultra-wideband radio-frequency (RF) signal that would convey the information that one seeks to communicate, and it would be required to couple differently delayed replicas of the RF signal to the radiating elements of a phased-array antenna. One or more of the proposed devices would be used to impose the delays and/or generate the delayed replicas of the RF-modulated optical pulse. The beam radiated or received by the antenna would be steered by use of a microprocessor-based control system that would adjust operational parameters of the devices to tune the delays to the required values. EIT is a nonlinear quantum optical interference effect that enables the propagation of light through an initially opaque medium. A suitable medium must have, among other properties, three quantum states (see Figure 1): an excited state (state 3), an upper ground state (state 2), and a lower ground state (state 1). These three states must form a closed system that exhibits no decays to other states in the presence of either or both of two laser beams: (1) a probe beam having the wavelength corresponding to the photon energy equal to the energy difference between states 3 and 1; and (2) a coupling beam having the wavelength corresponding to the photon energy equal to the energy difference between states 3 and 2. The probe beam is the one that is pulsed and modulated with an RF signal.

  14. Phylogenetic relationships of true butterflies (Lepidoptera: Papilionoidea) inferred from COI, 16S rRNA and EF-1α sequences.

    Science.gov (United States)

    Kim, Man Il; Wan, Xinlong; Kim, Min Jee; Jeong, Heon Cheon; Ahn, Neung-Ho; Kim, Ki-Gyoung; Han, Yeon Soo; Kim, Iksoo

    2010-11-01

    The molecular phylogenetic relationships among true butterfly families (superfamily Papilionoidea) have been a matter of substantial controversy; this debate has led to several competing hypotheses. Two of the most compelling of those hypotheses involve the relationships of (Nymphalidae + Lycaenidae) + (Pieridae + Papilionidae) and (((Nymphalidae + Lycaenidae) + Pieridae) + Papilionidae). In this study, approximately 3,500 nucleotide sequences from cytochrome oxidase subunit I (COI), 16S ribosomal RNA (16S rRNA), and elongation factor-1 alpha (EF-1α) were sequenced from 83 species belonging to four true butterfly families, along with those of three outgroup species belonging to three lepidopteran superfamilies. These sequences were subjected to phylogenetic reconstruction via Bayesian Inference (BI), Maximum Likelihood (ML), and Maximum Parsimony (MP) algorithms. The monophyletic Pieridae and monophyletic Papilionidae evidenced good recovery in all analyses, but in some analyses, the monophylies of the Lycaenidae and Nymphalidae were hampered by the inclusion of single species of the lycaenid subfamily Miletinae and the nymphalid subfamily Danainae. Excluding those singletons, all phylogenetic analyses among the four true butterfly families clearly identified the Nymphalidae as the sister to the Lycaenidae and identified this group as a sister to the Pieridae, with the Papilionidae identified as the most basal linage to the true butterfly, thus supporting the hypothesis: (Papilionidae + (Pieridae + (Nymphalidae + Lycaenidae))).

  15. Marker Assisted Selection can Reduce True as well as Pedigree Estimated Inbreeding

    DEFF Research Database (Denmark)

    Pedersen, L D; Sørensen, A C; Berg, P

    2009-01-01

    This study investigated whether selection using genotype information reduced the rate and level of true inbreeding, that is, identity by descent, at a selectively neutral locus as well as a locus under selection compared with traditional BLUP selection. In addition, the founder representation...... each of 40 herds. Selection was performed using BLUP, marker-assisted, or gene-assisted selection for a trait with low heritability (h2 = 0.04) only expressed in females, mimicking a health trait. The simulated genome consisted of 2 chromosomes. One biallelic quantitative trait loci (QTL......) with an initial frequency of the favorable allele of 0.1, and initially explaining 25% of the genetic variance as well as 4 markers were simulated in linkage disequilibrium, all positioned at chromosome 1. Chromosome 2 was selectively neutral, and consisted of a single neutral locus. The results showed...

  16. True beam commissioning experience at Nordland Hospital Trust, Norway

    Energy Technology Data Exchange (ETDEWEB)

    Daci, Lulzime, E-mail: lulzime.daci@nodlandssykehuset.no [Nordland Hospital Trust, Bodø (Norway); Malkaj, Partizan, E-mail: malkaj-p@hotmail.com [Faculty of Mathematics Engineering and Physics Engineering, Polytechnic University of Tirana (Albania)

    2016-03-25

    To evaluate the measured of all photon beam data of first Varian True Beam version 2.0 slim model, recently commissioned at Nordland Hospital Trust, Bodø. To compare and evaluate the possibility of beam matching with the Clinac2300, for the energies of 6MV and 15 MV. Materials/Methods: Measurements of PDD, OAR, and Output factors were realized with the IBA Blue-phantom with different detectors and evaluated between them for all photon energies: 6MV, 15MV, 6MV FFF and 10MV FFF. The ionization chambers used were Pin Point CC01, CC04, Semiflex CC13 and photon diode by Iba dosimetry. The data were processed using Beizer algorithm with a resolution of 1 mm. The measured depth dose curves, diagonals, OAR, and output factors were imported into Eclipse in order to calculate beam data for the anisotropic analytical algorithm (AAA version 10.0.28) for both the dataset measured with CC04 and CC13 and compared. The model head of 23EX was selected as the most near model to True Beam as a restriction of our version of Aria. It was seen that better results were achieved with the CC04 measured data as a result of better resolution. For the biggest field after 10 cm depth a larger difference is seen between measured and calculated for both dataset, but it is within the criteria for acceptance. Results: The Beam analysis criteria of 2 mm at 50% dose is achieved for all the fields accept for 40x40 that is within 3%. Depth difference at maximum dose is within 1 mm for all the fields and dose difference at 100 mm and 200 mm is lower than 1% for or all the fields. The PDD between two machines for all the fields differ after Dmax with less than 1%. For profiles in the field zone and outside field the difference is within 1% for all the fields. In the penumbra region the difference is from 2% up to 12% for big fields. As for diagonals they differ as a result of the head construction at the edge of the field and the penumbra region. The output factors differ for big fields

  17. True beam commissioning experience at Nordland Hospital Trust, Norway

    International Nuclear Information System (INIS)

    Daci, Lulzime; Malkaj, Partizan

    2016-01-01

    To evaluate the measured of all photon beam data of first Varian True Beam version 2.0 slim model, recently commissioned at Nordland Hospital Trust, Bodø. To compare and evaluate the possibility of beam matching with the Clinac2300, for the energies of 6MV and 15 MV. Materials/Methods: Measurements of PDD, OAR, and Output factors were realized with the IBA Blue-phantom with different detectors and evaluated between them for all photon energies: 6MV, 15MV, 6MV FFF and 10MV FFF. The ionization chambers used were Pin Point CC01, CC04, Semiflex CC13 and photon diode by Iba dosimetry. The data were processed using Beizer algorithm with a resolution of 1 mm. The measured depth dose curves, diagonals, OAR, and output factors were imported into Eclipse in order to calculate beam data for the anisotropic analytical algorithm (AAA version 10.0.28) for both the dataset measured with CC04 and CC13 and compared. The model head of 23EX was selected as the most near model to True Beam as a restriction of our version of Aria. It was seen that better results were achieved with the CC04 measured data as a result of better resolution. For the biggest field after 10 cm depth a larger difference is seen between measured and calculated for both dataset, but it is within the criteria for acceptance. Results: The Beam analysis criteria of 2 mm at 50% dose is achieved for all the fields accept for 40x40 that is within 3%. Depth difference at maximum dose is within 1 mm for all the fields and dose difference at 100 mm and 200 mm is lower than 1% for or all the fields. The PDD between two machines for all the fields differ after Dmax with less than 1%. For profiles in the field zone and outside field the difference is within 1% for all the fields. In the penumbra region the difference is from 2% up to 12% for big fields. As for diagonals they differ as a result of the head construction at the edge of the field and the penumbra region. The output factors differ for big fields

  18. Fault Rock Zones Characterisation - Final report. TRUE-1 Continuation Project

    International Nuclear Information System (INIS)

    Winberg, Anders

    2010-11-01

    At the conclusion of the TRUE-1 and TRUE Block Scale experimental programmes at the Aespoe Hard Rock Laboratory one remaining identified uncertainty was the in situ internal structure of conductive structures, and in particular the in situ material properties of unconsolidated fault gouge of such conductive structures. With the aim of reducing these uncertainties an experimental program has been conducted at depth in the Aespoe Hard Rock Laboratory. Four conductive structures in the immediate vicinity of the Aespoe tunnel were identified for further study. Following basic geometrical and geological modelling based on tunnel observations, geological/ mineralogical and hydrogeological investigations in four boreholes at each site, epoxy resin was injected in selected packed off borehole sections containing the structure. Following a sufficient time for curing of the epoxy, the injected borehole 72 mm sections were overcored with a 300 mm core barrel. Customised techniques were employed to section the core in the borehole and for its retrieval out of the borehole. Following basic geological mapping, selected overcores were sectioned and were subject to image analysis to assess the pore structure using a variety of different descriptive geometrical attributes. In addition, an attempt was made to infer the porosity of the fault rock (including fault gouge) using binary images. Since analysis has been made on multiple slices of impregnated rock it is also possible to crudely map the 3D variability of a given entity. It was furthermore identified that porosity estimates, which range from some 10-70% are, apart from being dependent on the penetration of the epoxy, dependent on the resolution of the given image, the size of the averaging window, and the porosity components contained therein. The obtained quantifications of porosity can therefore only be regarded as ball-park relative porosities of a complete fault rock zones. It does not, however, provide firm

  19. Fault Rock Zones Characterisation - Final report. TRUE-1 Continuation Project

    Energy Technology Data Exchange (ETDEWEB)

    Winberg, Anders (ed.) (Conterra AB (Sweden))

    2010-11-15

    At the conclusion of the TRUE-1 and TRUE Block Scale experimental programmes at the Aespoe Hard Rock Laboratory one remaining identified uncertainty was the in situ internal structure of conductive structures, and in particular the in situ material properties of unconsolidated fault gouge of such conductive structures. With the aim of reducing these uncertainties an experimental program has been conducted at depth in the Aespoe Hard Rock Laboratory. Four conductive structures in the immediate vicinity of the Aespoe tunnel were identified for further study. Following basic geometrical and geological modelling based on tunnel observations, geological/ mineralogical and hydrogeological investigations in four boreholes at each site, epoxy resin was injected in selected packed off borehole sections containing the structure. Following a sufficient time for curing of the epoxy, the injected borehole 72 mm sections were overcored with a 300 mm core barrel. Customised techniques were employed to section the core in the borehole and for its retrieval out of the borehole. Following basic geological mapping, selected overcores were sectioned and were subject to image analysis to assess the pore structure using a variety of different descriptive geometrical attributes. In addition, an attempt was made to infer the porosity of the fault rock (including fault gouge) using binary images. Since analysis has been made on multiple slices of impregnated rock it is also possible to crudely map the 3D variability of a given entity. It was furthermore identified that porosity estimates, which range from some 10-70% are, apart from being dependent on the penetration of the epoxy, dependent on the resolution of the given image, the size of the averaging window, and the porosity components contained therein. The obtained quantifications of porosity can therefore only be regarded as ball-park relative porosities of a complete fault rock zones. It does not, however, provide firm

  20. Diagnostic pitfalls associated with a large true posterior communicating artery aneurysm: a case report.

    Science.gov (United States)

    Nagatani, Kimihiro; Otani, Naoki; Seno, Soichiro; Takeuchi, Satoru; Wada, Kojiro; Mori, Kentaro

    2013-10-01

    True posterior communicating artery (PCoA) aneurysm is an aneurysm that originates from the PCoA, and large or giant true PCoA aneurysms are rare. We report a case of a large true PCoA aneurysm successfully clipped after anterior clinoidectomy and discuss the diagnostic pitfalls associated with this rare clinical entity.

  1. Imaging diagnosis--positive contrast peritoneographic features of true diaphragmatic hernia.

    Science.gov (United States)

    Choi, Jihye; Kim, Hyunwook; Kim, Mieun; Yoon, Junghee

    2009-01-01

    A true diaphragmatic hernia is a congenital diaphragmatic malformation that can appear identical to a peritoneopericardial diaphragmatic hernia (PPDH). True diaphragmatic hernias are rare in dogs. Herein we describe the use of positive contrast peritoneography for diagnosis of a true diaphragmatic hernia in two dogs.

  2. Effects of sulpiride on true and false memories of thematically related pictures and associated words in healthy volunteers

    Directory of Open Access Journals (Sweden)

    Regina V Guarnieri

    2016-03-01

    Full Text Available Episodic memory, working memory, emotional memory and attention are subject to dopaminergic modulation. However, the potential role of dopamine on the generation of false memories is unknown. This study defined the role of the dopamine D2 receptor on true and false memories. Twenty-four young, healthy volunteers ingested a single dose of placebo or 400 mg oral sulpiride, a dopamine D2-receptor antagonist, just before starting the recognition memory task in a randomized, double-blind, placebo-controlled trial. The sulpiride group made more false recognitions during visual and verbal processing than the placebo group although both groups had the same indices of true memory. These findings demonstrate that dopamine blockade in healthy volunteers can specifically increase the rate of false recognitions.

  3. Management of unilateral true vocal cord paralysis in children.

    Science.gov (United States)

    Setlur, Jennifer; Hartnick, Christopher J

    2012-12-01

    Historically, information gained from the treatment of unilateral true vocal cord paralysis (UVCP) in adults was the same used to treat children. Today, there is a growing body of literature aimed specifically at the treatment of this condition in children. It is an area of growing interest as UVCP can significantly impact a child's quality of life. Children with UVCP may present with stridor, dysphonia, aspiration, feeding difficulties, or a combination of these symptoms. Diagnosis relies on laryngoscopy, but other adjuncts such as ultrasound and laryngeal electromyography may also be helpful in making the diagnosis and forming a treatment plan. In many instances, there is effective compensation by the contralateral vocal fold, making surgical intervention unnecessary. Children who cannot compensate for a unilateral defect may suffer from significant dysphonia that can affect their quality of life because their ability to be understood may be diminished. In these patients, treatment in the form of medialization or reinnervation of the affected recurrent laryngeal nerve may be warranted. UVCP is a well recognized problem in pediatric patients with disordered voice and feeding problems. Some patients will spontaneously recover their laryngeal function. For those who do not, a variety of reliable techniques are available for rehabilitative treatment. Improved diagnostics and a growing understanding of prognosis can help guide therapy decisions along with the goals and desires of the patient and his or her family.

  4. Reaching for the true overlay in advanced nodes

    Science.gov (United States)

    Koay, Chiew-seng; Hamieh, Bassem; Felix, Nelson; Gaudiello, John

    2017-03-01

    Traditionally, the total measurement uncertainty (TMU) of overlay metrology focuses on dynamic precision, toolinduced-shift, and matching, while rarely examining inaccuracy. However, some researchers have recently shown that measurement inaccuracy can still be large despite optimized small TMU. Moreover, this inaccuracy can consume a significant portion of the overlay budget in the advanced nodes. In addition to qualifying the overlay error of inline wafers, overlay metrology is also used for improving on-product overlay as it provides corrective feedback to the lithography scanner. The accuracy of the correction terms as a result depends directly upon the measurement accuracy. As such, enhanced overlay accuracy will improve the overlay performance of reworked wafers, or subsequently exposed wafers. We have previously shown that a segmented Blossom target is more prone to asymmetry-induced inaccuracy than a nonsegmented target is [1]. Since target segmentation is inevitable for SADP and SAQP patterning processes, their resulting overlay performance leaves a lot to be desired. In our quest to reach for the true overlay, this paper reports our investigations on accuracy enhancement techniques for image-based targets, such as redundancy and self-calibration, and on the use of simulation-optimized scatterometry-based targets.

  5. True-personality-assisted self-awareness expert system

    International Nuclear Information System (INIS)

    Laleuf, M.

    1988-01-01

    Based on psychoanalytic theory, the Who am I? expert system explains in simple terms the individual's true personality, even it its unconscious or hidden aspects. Our overt personality traits are deeply rooted. The Who am I? expert system gives access to an individual's primary personality, starting from his habitual everyday-life behavior: (1) describes the individual's basic personality, (2) explains this personality through the individual's deeply rooted experience and motivation, and (3) makes links with other people with a similar profile. The following are the primary features of the system: easy individual access, results in <20 minutes, and guaranteed confidentiality. Business applications include the following: (1) Individual training: Self-awareness improves a person's ability to fit in and to succeed within the group. (2) Communication: a homogeneous team has a better chance of success. (3) Human reliability: A close-knit team remains reliable even when faced with serious difficulties. (4) Recruitment: This technique enables the selection of individuals who will fit an existing homogeneous team. The system also enables a psychological diagnosis to be confirmed

  6. Ethics in medicine: students' opinions on disclosure of true diagnosis.

    Science.gov (United States)

    Pulanić, Drazen; Vrazić, Hrvoje; Cuk, Mario; Petrovecki, Mladen

    2002-02-01

    To determine students opinions about diagnosis disclosure to the patient and other interested parties. During 2000/2001 academic year, an anonymous survey was conducted among the first-year (200 questionnaires) and sixth-year medical students (200 questionnaires) at the Zagreb University School of Medicine. Students were asked what they would say about the diagnosis to the patient, patients family, friend, employer, colleague from work, health insurance agent, another physician, or medical student, if the diagnosis was inoperable lung carcinoma in a 20- and 66-year-old patient vs bacterial pneumonia in patients of the same age. The possibilities were to tell the truth, lie, or refuse to disclose the diagnosis. The response rate was 55%. Students would disclose the true diagnosis to the patient, patients family, friend, and employer in case of benign disease more often than in case of malignant disease (pemployer, and rarely to the patient's colleague from work. First-year students would generally tell the truth more often than sixth-year students (pethical issues should be discussed during the studies.

  7. TRUE AND FAIR VIEW – THE SUPREM TRUTH IN ACCOUNTING?

    Directory of Open Access Journals (Sweden)

    Ana-Maria MARCULESCU

    2013-06-01

    Full Text Available Acting in a social and economic environment in a continuous movement and transformation, accounting is experiencing with new situations, in its attempt to answer all functions and information users that it generates, making it an important arbitration instrument in the game of those involved in business world. The main characteristic of accounting is represented by providing useful information retrodictive and predictive in an efficient and economic decision process regarding the economic entity's financial position and accounting performance. Under these circumstances, the information must not contain significant errors, is not biased, and users can be confident that it accurately represents what they proposed to represent, or what is expected, in a reasonably manner to be. Fair and true view seen as an ideal to which any professional accountant should aim, seems to be more difficult to achieve under the current conditions, in which fiscal pressure is more and more unbearable and top management is more and more willing to make compromises that sometimes are at a legal limit. In theory, it is well known that registrations and accounting reports must provide a clear image, honest, fair and full on the assets, financial position and results of the entity. In practice, contrary to ethical principles, more and more "servants" of the accounting profession are either willing, or forced to submit distorted accounting information giving the impression of calmness to a disastrous situation.

  8. Open Pollinated Offspring for Producing Potatoes from True Seed

    Directory of Open Access Journals (Sweden)

    Golmirzaie, AM.

    2004-01-01

    Full Text Available Open pollinated (OP offspring offers a cheap propagule for potato production from true seed (TPS. A series of trials in contrasting Peruvian locations including several generations derived by open pollination were carried out to determine the potential of OP for TPS. The results suggest that several generations of OP did not affect the performance of TPS for tuber characteristics. On average, F1 hybrids out-yielded first generation OP offspring, but tuber yield per plot of advanced OP generations (OP5 across locations did not differ significantly from that shown by F1 hybrids. It seems that the effect of potential inbreeding in early OP generations was absent in advanced OP generations, maybe due to selection of heterozygous parents in the preceding generations. Results from sequential harvests showed that initiation and bulking of tubers are slower in advanced generations of OP than in the first OP generation, particularly in the warm tropics. Nonetheless, some OP TPS did not differ significantly for tuber yield across generations, suggesting that farmers may grow commercially selected OP offspring.

  9. Using Shakespeare's Sotto Voce to Determine True Identity From Text

    Directory of Open Access Journals (Sweden)

    David Kernot

    2018-03-01

    Full Text Available Little is known of the private life of William Shakespeare, but he is famous for his collection of plays and poems, even though many of the works attributed to him were published anonymously. Determining the identity of Shakespeare has fascinated scholars for 400 years, and four significant figures in English literary history have been suggested as likely alternatives to Shakespeare for some disputed works: Bacon, de Vere, Stanley, and Marlowe. A myriad of computational and statistical tools and techniques have been used to determine the true authorship of his works. Many of these techniques rely on basic statistical correlations, word counts, collocated word groups, or keyword density, but no one method has been decided on. We suggest that an alternative technique that uses word semantics to draw on personality can provide an accurate profile of a person. To test this claim, we analyse the works of Shakespeare, Christopher Marlowe, and Elizabeth Cary. We use Word Accumulation Curves, Hierarchical Clustering overlays, Principal Component Analysis, and Linear Discriminant Analysis techniques in combination with RPAS, a multi-faceted text analysis approach that draws on a writer's personality, or self to identify subtle characteristics within a person's writing style. Here we find that RPAS can separate the known authored works of Shakespeare from Marlowe and Cary. Further, it separates their contested works, works suspected of being written by others. While few authorship identification techniques identify self from the way a person writes, we demonstrate that these stylistic characteristics are as applicable 400 years ago as they are today and have the potential to be used within cyberspace for law enforcement purposes.

  10. Kocuria kristinae: a true pathogen in pediatric patients.

    Science.gov (United States)

    Chen, Hsin-Mao; Chi, Hsin; Chiu, Nan-Chang; Huang, Fu-Yuan

    2015-02-01

    Kocuria kristinae is a Gram-positive microorganism, which has rarely been reported as a pathogen that causes infection in humans. Recently, a few studies had concluded that this pathogen can indeed cause infection in immunocompromised hosts. However, the number of reports on K. kristinae infection in pediatric patients is still relatively limited. Clinical data on pediatric patients who had K. kristinae cells isolated from their blood specimens during the period from January 2008 to May 2012 in a tertiary-care hospital in northern Taiwan were gathered and analyzed. Among 12 patients with K. kristinae cells isolated from their blood specimens, laboratory test results confirmed seven to have K. kristinae bloodstream infection. Six of them were premature babies, and one had acute leukemia. The infections were all healthcare associated. All the six premature babies had clinical presentation of sepsis and were inserted with percutaneous central venous catheters. One patient had two sets of blood culture positive for K. kristinae infection, and two premature patients had two sets of K. kristinae isolated, one from blood culture and the other from catheter tip culture, both of which were done at the same time. The leukemic child was inserted with a Broviac catheter and had K. kristinae isolated from both blood specimen and Broviac catheter. In the remaining five patients, K. kristinae infection was considered to be contaminant because they had only one set of positive blood culture and had other recognized infections. K. kristinae can cause infections in premature babies and immunocompromised pediatric patients using long-term intravenous catheters. Therefore, K. kristinae should be considered as a true pathogen and proper treatment should be provided to all susceptible pediatric patients. Copyright © 2013. Published by Elsevier B.V.

  11. Using Shakespeare's Sotto Voce to Determine True Identity From Text

    Science.gov (United States)

    Kernot, David; Bossomaier, Terry; Bradbury, Roger

    2018-01-01

    Little is known of the private life of William Shakespeare, but he is famous for his collection of plays and poems, even though many of the works attributed to him were published anonymously. Determining the identity of Shakespeare has fascinated scholars for 400 years, and four significant figures in English literary history have been suggested as likely alternatives to Shakespeare for some disputed works: Bacon, de Vere, Stanley, and Marlowe. A myriad of computational and statistical tools and techniques have been used to determine the true authorship of his works. Many of these techniques rely on basic statistical correlations, word counts, collocated word groups, or keyword density, but no one method has been decided on. We suggest that an alternative technique that uses word semantics to draw on personality can provide an accurate profile of a person. To test this claim, we analyse the works of Shakespeare, Christopher Marlowe, and Elizabeth Cary. We use Word Accumulation Curves, Hierarchical Clustering overlays, Principal Component Analysis, and Linear Discriminant Analysis techniques in combination with RPAS, a multi-faceted text analysis approach that draws on a writer's personality, or self to identify subtle characteristics within a person's writing style. Here we find that RPAS can separate the known authored works of Shakespeare from Marlowe and Cary. Further, it separates their contested works, works suspected of being written by others. While few authorship identification techniques identify self from the way a person writes, we demonstrate that these stylistic characteristics are as applicable 400 years ago as they are today and have the potential to be used within cyberspace for law enforcement purposes. PMID:29599734

  12. Hydrodynamic perception in true seals (Phocidae) and eared seals (Otariidae).

    Science.gov (United States)

    Hanke, Wolf; Wieskotten, Sven; Marshall, Christopher; Dehnhardt, Guido

    2013-06-01

    Pinnipeds, that is true seals (Phocidae), eared seals (Otariidae), and walruses (Odobenidae), possess highly developed vibrissal systems for mechanoreception. They can use their vibrissae to detect and discriminate objects by direct touch. At least in Phocidae and Otariidae, the vibrissae can also be used to detect and analyse water movements. Here, we review what is known about this ability, known as hydrodynamic perception, in pinnipeds. Hydrodynamic perception in pinnipeds developed convergently to the hydrodynamic perception with the lateral line system in fish and the sensory hairs in crustaceans. So far two species of pinnipeds, the harbour seal (Phoca vitulina) representing the Phocidae and the California sea lion (Zalophus californianus) representing the Otariidae, have been studied for their ability to detect local water movements (dipole stimuli) and to follow hydrodynamic trails, that is the water movements left behind by objects that have passed by at an earlier point in time. Both species are highly sensitive to dipole stimuli and can follow hydrodynamic trails accurately. In the individuals tested, California sea lions were clearly more sensitive to dipole stimuli than harbour seals, and harbour seals showed a superior trail following ability as compared to California sea lions. Harbour seals have also been shown to derive additional information from hydrodynamic trails, such as motion direction, size and shape of the object that caused the trail (California sea lions have not yet been tested). The peculiar undulated shape of the harbour seals' vibrissae appears to play a crucial role in trail following, as it suppresses self-generated noise while the animal is swimming.

  13. Radar speed gun true velocity measurements of sports-balls in flight: application to tennis

    International Nuclear Information System (INIS)

    Robinson, Garry; Robinson, Ian

    2016-01-01

    Spectators of ball-games often seem to be fascinated by the speed of delivery of the ball. They appear to be less interested in or even oblivious to the mechanism and accuracy of the measurement or where in the flight path of the ball the measurement is actually made. Radar speed guns using the Doppler effect are often employed for such speed measurements. It is well known that such guns virtually always measure the line-of-sight or radial velocity of the ball and as such will return a reading less than or equal to the true speed of the ball. In this paper, using only basic physics principles we investigate such measurements, in particular those associated with the service stroke in tennis. For the service trajectories employed here, a single radar gun located in line with the centre-line of the court in fact under-estimates the speed of a wide serve by about 3.4% at the point of delivery, and by about 14.3% on impact with the court. However, we demonstrate that both the magnitude and direction of the true velocity of the ball throughout its entire flight path may be obtained, at least in principle, by the use of four suitably placed radar speed guns. These four guns must be able to measure the ‘range’ to the ball, enabling its position in flight to be determined, and three of them must be able to measure the radial velocity of the ball. Restrictions on the locations of the speed guns are discussed. Such restrictions are quite liberal, although there are certain configurations of the radar gun positions which cannot be used. Importantly, with the one proviso that no speed gun can be directly in the path of the ball (not only for the obvious reasons), we find that if the speed of the ball can be determined for one point in the trajectory, it can also be determined for all points. The accuracy of the range and radial velocity measurements required to give meaningful results for the true velocity are also briefly discussed. It is found that the accuracy required

  14. Arterial spin labelling perfusion MRI of breast cancer using FAIR TrueFISP: Initial results

    International Nuclear Information System (INIS)

    Buchbender, S.; Obenauer, S.; Mohrmann, S.; Martirosian, P.; Buchbender, C.; Miese, F.R.; Wittsack, H.J.; Miekley, M.; Antoch, G.; Lanzman, R.S.

    2013-01-01

    Aim: To assess the feasibility of an unenhanced, flow-sensitive, alternating inversion recovery-balanced steady-state free precession (FAIR TrueFISP) arterial spin labelling (ASL) magnetic resonance imaging (MRI) technique for quantification of breast cancer perfusion. Materials and methods: Eighteen untreated breast tumour patients (mean age 53 ± 17 years, range 30–68 years) and four healthy controls (mean age 51 ± 14 years, range 33–68 years) were enrolled in this study and were imaged using a clinical 1.5 T MRI machine. Perfusion measurements were performed using a coronal single-section ASL FAIR TrueFISP technique in addition to a routine breast MRI examination. T1 relaxation time of normal breast parenchyma was determined in four healthy volunteers using the variable flip angle approach. The definitive diagnosis was obtained at histology after biopsy or surgery and was available for all patients. Results: ASL perfusion was successfully acquired in 13 of 18 tumour patients and in all healthy controls. The mean ASL perfusion of invasive ductal carcinoma tissue was significantly higher (88.2 ± 39.5 ml/100 g/min) compared to ASL perfusion of normal breast parenchyma (24.9 ± 12.7 ml/100 g/min; p < 0.05) and invasive lobular carcinoma (30.5 ± 4.3 ml/100 g/min; p < 0.05). No significant difference was found between the mean ASL perfusion of normal breast parenchyma and invasive lobular carcinoma tissue (p = 0.97). Conclusion: ASL MRI enables quantification of breast cancer perfusion without the use of contrast material. However, its impact on diagnosis and therapy management of breast tumours has to be evaluated in larger patient studies

  15. True Polar Wander of Enceladus From Topographic Data

    Science.gov (United States)

    Tajeddine, Radwan; Soderlund, Krista M.; Thomas, Peter C.; Helfenstein, Paul; Hedman, Matthew M.; Burns, Joseph A.; Schenk, Paul M.

    2016-10-01

    Besides the relative motion of lithospheric plates, the Earth as a whole moves with respect to its rotation pole, as shown by paleomagnetic, astrometric and geodetic measurements [1]. Such so-called true polar wander (TPW) occurs because our planet's moments of inertia change temporally owing to internal thermal convection and to the redistribution of surficial mass during ice ages. Thus, to conserve angular momentum while losing rotational energy, Earth's axis of maximum moment of inertia aligns with its spin axis. Theoreticians suspect similar reorientations of other celestial bodies but supporting evidence is fragmentary, at best [2]. Here we report the discovery of a global series of topographic lows on Saturn's satellite Enceladus indicating that this synchronously locked moon has undergone reorientation by ~55°. We use improved topographic data from spherical harmonic expansion of Cassini limb [3,4,5] and stereogrammetric [5,6,7] measurements to characterize regional topography over the surface of Enceladus. We identify a group of nearly antipodal basins orthogonal to a topographic basin chain tracing a non-equatorial circumglobal belt across Enceladus' surface. We argue that the belt and the antipodal regions are fossil remnants of old equator and poles, respectively. These lows are argued to arise from isostasic compensation [7,8] with their pattern reflecting variations in internal dynamics of the ice shell. Our hypothesis is consistent with many geological features visible in Cassini images [9].References:[1] Mitrovica, J.X. & Wahr, Annual Review of Earth and Planetary Sciences, 39, 577-616 (2011).[2] Matsuyama, I. et al. Annual Review of Earth and Planetary Sciences, 42, 605-634 (2014).[3] Thomas, P.C. et al. Icarus, 190, 573-584 (2007).[4] Thomas, P.C. Icarus, 208, 395-401 (2010).[5] Thomas, P.C. et al. Icarus, 264, 37-47 (2016).[6] Edwards, K. Photogrammetric Engineering and Remote Sensing, 53, 1219-1222 (1987).[7] Schenk, P.M. & McKinnon, W. B

  16. Theranostics with radiation-induced ultrasound emission (TRUE

    Directory of Open Access Journals (Sweden)

    Elijah Robertson

    2018-05-01

    Full Text Available Two novel ultrasound imaging techniques with imaging contrast mechanisms are in the works: X-ray-induced acoustic computed tomography (XACT, and nanoscale photoacoustic tomography (nPAT. XACT has incredible potential in: (1 biomedical imaging, through which a 3D image can be generated using only a single X-ray projection, and (2 radiation dosimetry. nPAT as a new alternative of super-resolution microscopy can break through the optical diffraction limit and is capable of exploring sub-cellular structures without reliance on fluorescence labeling. We expect these new imaging techniques to find widespread applications in both pre-clinical and clinical biomedical research.

  17. Hippocampal size is related to short-term true and false memory, and right fusiform size is related to long-term true and false memory.

    Science.gov (United States)

    Zhu, Bi; Chen, Chuansheng; Loftus, Elizabeth F; He, Qinghua; Lei, Xuemei; Dong, Qi; Lin, Chongde

    2016-11-01

    There is a keen interest in identifying specific brain regions that are related to individual differences in true and false memories. Previous functional neuroimaging studies showed that activities in the hippocampus, right fusiform gyrus, and parahippocampal gyrus were associated with true and false memories, but no study thus far has examined whether the structures of these brain regions are associated with short-term and long-term true and false memories. To address that question, the current study analyzed data from 205 healthy young adults, who had valid data from both structural brain imaging and a misinformation task. In the misinformation task, subjects saw the crime scenarios, received misinformation, and took memory tests about the crimes an hour later and again after 1.5 years. Results showed that bilateral hippocampal volume was associated with short-term true and false memories, whereas right fusiform gyrus volume and surface area were associated with long-term true and false memories. This study provides the first evidence for the structural neural bases of individual differences in short-term and long-term true and false memories.

  18. Estimating true instead of apparent survival using spatial Cormack-Jolly-Seber models

    Science.gov (United States)

    Schaub, Michael; Royle, J. Andrew

    2014-01-01

    Survival is often estimated from capture–recapture data using Cormack–Jolly–Seber (CJS) models, where mortality and emigration cannot be distinguished, and the estimated apparent survival probability is the product of the probabilities of true survival and of study area fidelity. Consequently, apparent survival is lower than true survival unless study area fidelity equals one. Underestimation of true survival from capture–recapture data is a main limitation of the method.

  19. TrueFisp versus HASTE sequences in 3T cine MRI: Evaluation of image quality during phonation in patients with velopharyngeal insufficiency

    International Nuclear Information System (INIS)

    Kulinna-Cosentini, Christiane; Czerny, Christian; Weber, Michael; Baumann, Arnulf; Sinko, Klaus

    2016-01-01

    To evaluate the image quality of two fast dynamic magnetic resonance imaging (MRI) sequences: True fast imaging with steady state precession (TrueFisp) was compared with half-Fourier acquired single turbo-spin-echo (HASTE) sequence for the characterization of velopharyngeal insufficiency (VPI) in repaired cleft palate patients. Twenty-two patients (10 female and 12 male; mean age, 17.7 ± 10.6 years; range, 9-31) with suspected VPI underwent 3-T MRI using TrueFisp and HASTE sequences. Imaging was performed in the sagittal plane at rest and during phonation of ''ee'' and ''k'' to assess the velum, tongue, posterior pharyngeal wall and a potential VP closure. The results were analysed independently by one radiologist and one orthodontist. HASTE performed better than TrueFisp for all evaluated items, except the tongue evaluation by the orthodontist during phonation of ''k'' and ''ee''. A statistically significant difference in favour of HASTE was observed in assessing the velum at rest and during phonation of ''k'' and ''ee'', and also in assessing VP closure in both raters (p < 0.05). TrueFisp imaging was twice as fast as HASTE (0.36 vs. 0.75 s/image). Dynamic HASTE images were of superior quality to those obtained with TrueFisp, although TrueFisp imaging was twice as fast. (orig.)

  20. Micropropagation and Biomass Production of True-to-Type Stevia rebaudiana Bertoni.

    Science.gov (United States)

    Modi, Arpan R; Sharma, Vikas; Patil, Ghanshyam; Singh, Amritpal S; Subhash, N; Kumar, Nitish

    2016-01-01

    Here we describe an efficient micropropagation protocol for Stevia rebaudiana Bertoni. We present experiments carried out to optimize the suitable media for in vitro shoot multiplication and root induction and to study the effect of culture vessel on shoot multiplication. Among all different media tested for in vitro shoot multiplication, hormone-free liquid medium is most suitable. The highest number of nodes per shoot (5.4) and length of shoot (4.76 cm) at 4 weeks after subculturing are observed when single node explants are placed on modified MS medium supplemented with 1 % sucrose and 0.7 % agar. The highest response of multiplication rate (9.56) is observed on half strength of macroelement of MS with full strength of microelement of MS and 170 mg/l KH2PO4, and 185 mg/l MgSO4 in plastic growth container. Further, RAPD marker analysis of in vitro-raised plants maintained their clonal fidelity and true-to-type without showing any somaclonal variation.

  1. Accurate decisions in an uncertain world: collective cognition increases true positives while decreasing false positives

    NARCIS (Netherlands)

    Wolf, M.; Kurvers, R.H.J.M.; Ward, A.J.W.; Krause, S.; Krause, J.

    2013-01-01

    In a wide range of contexts, including predator avoidance, medical decision-making and security screening, decision accuracy is fundamentally constrained by the trade-off between true and false positives. Increased true positives are possible only at the cost of increased false positives;

  2. Developmentally Invariant Dissociations in Children's True and False Memories: Not All Relatedness Is Created Equal

    Science.gov (United States)

    Howe, Mark L.

    2006-01-01

    The role of categorical versus associative relations in 5-, 7-, and 11-year-old children's true and false memories was examined using the Deese--Roediger--McDermott (DRM) paradigm and categorized lists of pictures or words with or without category labels as primes. For true items, recall increased with age and categorized lists were better…

  3. Estimating True Short-Term Consistency in Vocational Interests: A Longitudinal SEM Approach

    Science.gov (United States)

    Gaudron, Jean-Philippe; Vautier, Stephane

    2007-01-01

    This study aimed at estimating the correlation between true scores (true consistency) of vocational interest over a short time span in a sample of 1089 adults. Participants were administered 54 items assessing vocational, family, and leisure interests twice over a 1-month period. Responses were analyzed with a multitrait (MT) model, which supposes…

  4. Measuring True Sales and Underreporting with Matched Firm-Level Survey and Tax-Office Data

    NARCIS (Netherlands)

    Zhou, F.; Oostendorp, R.H.

    2014-01-01

    This paper uses firm-level survey data matched with official tax records to estimate the unobserved true sales of formal firms in Mongolia. Taking into account firm-level incentives to comply with taxes and a production function technology linking unobserved true sales with observable firm-level

  5. Filing false vice reports: Distinguishing true from false allegations of rape

    NARCIS (Netherlands)

    de Zutter, A.; Horselenberg, R.; van Koppen, P.J.

    2017-01-01

    False allegations constitute a problem since they may cause harm. To study the difference between true and false allegations we used a quasi-experimental approach. In the control condition likely true allegations were retrieved from criminal files. The victims, all female, were between the ages of

  6. A computer simulation approach to quantify the true area and true area compressibility modulus of biological membranes

    International Nuclear Information System (INIS)

    Chacón, Enrique; Tarazona, Pedro; Bresme, Fernando

    2015-01-01

    We present a new computational approach to quantify the area per lipid and the area compressibility modulus of biological membranes. Our method relies on the analysis of the membrane fluctuations using our recently introduced coupled undulatory (CU) mode [Tarazona et al., J. Chem. Phys. 139, 094902 (2013)], which provides excellent estimates of the bending modulus of model membranes. Unlike the projected area, widely used in computer simulations of membranes, the CU area is thermodynamically consistent. This new area definition makes it possible to accurately estimate the area of the undulating bilayer, and the area per lipid, by excluding any contributions related to the phospholipid protrusions. We find that the area per phospholipid and the area compressibility modulus features a negligible dependence with system size, making possible their computation using truly small bilayers, involving a few hundred lipids. The area compressibility modulus obtained from the analysis of the CU area fluctuations is fully consistent with the Hooke’s law route. Unlike existing methods, our approach relies on a single simulation, and no a priori knowledge of the bending modulus is required. We illustrate our method by analyzing 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine bilayers using the coarse grained MARTINI force-field. The area per lipid and area compressibility modulus obtained with our method and the MARTINI forcefield are consistent with previous studies of these bilayers

  7. THE CONFLICT BETWEEN THE TRUE AND FAIR VIEW AND THE PRUDENCE IN ROMANIAN ACCOUNTING

    Directory of Open Access Journals (Sweden)

    Violeta Isai

    2015-05-01

    Full Text Available In the accounts of Romania, the principle of true and fair view and the prudence principle are in a relationship of mutual conditioning. True and fair view has its origins in Anglo-Saxon accounting, the British, and English translation of the expression is "true and fair view". In the context of Romania's national, a first reference to the concept of true and fair view a we identify in the root Accounting Law No 82/1991 which lays down that objective accounting- ensuring accurate image, clear, and complete heritage of the financial situation and the results. Prudence is to be found in sincerity (in the direction of the present in the financial statements facts which might influence the recipient information and should serve the concept of true and fair view.

  8. Tamarugite from Diana Cave (SW Romania) -first true karst occurrence

    Science.gov (United States)

    Pušcaš, C. M.; Onac, B. P.; Effenberger, H. S.; Povarǎ, I.

    2012-04-01

    Diana Cave is located within the town limits of Baile Herculane (SW Romania) and develops as a 14 m long, westward oriented, unique passage guided by the Diana fault [1]. At the far end of the cave, the thermo-mineral Diana Spring wells forth. In the early 1970s a mine gallery that intersected the cave was created to drain the water into a pumping station and the original cave passage was somewhat altered and reinforced with concrete. Today the concrete and the silty limestone cave walls are heavily corroded by H2SO4 outgassing from the hot water (ca. 50°C) and display abundant gypsum crusts, soggy aggregates of native S, and a variety of more exotic sulfates. Among them, a mineral that has been previously identified in caves only in connection to volcanic activity, either as thermal springs or fumaroles [2]: tamarugite [NaAl(SO4)26H2O]. It was [3] that first mentioned the occurrence of this Na and Al sulfate in Diana Cave, our research aiming to give a detailed description of this mineral, its paragenesis, and mechanisms of precipitation. Recently, tamarugite has also been identified in a sulfuric acid cave from Greece [4]. Along with powder X-ray diffractions coupled with Rietveld refinement, scanning electron microscope, and electron probe micro-analysis, δ18O and δ34S compositions of the sulfate mineral as well as precipitates from the water were analyzed to identify and better constrain the genesis of this rare sulfate. Regrettably, the crystal size of our specimens is inappropriate for identification by means of single crystal X-ray diffraction. Physical and chemical parameters of Diana Spring were as well measured on several occasions. Geochemical analysis suggests that the minute, white tamarugite flakes precipitated in Diana Cave as a result of the interactions between the thermo-mineral water or water vapor and the original limestone bedrock and concrete that blankets the mine gallery. [1] Povara, I., Diaconu, G., Goran, C. (1972). Observations pr

  9. Usefulness of true FISP cine MR imaging in patients with poor cardiac function

    Energy Technology Data Exchange (ETDEWEB)

    Sakuma, Toshiharu; Yamada, Naoaki; Motooka, Makoto; Enomoto, Naoyuki; Maeshima, Isamu; Matsuda, Kazuhide; Urayama, Shinichi; Ikeo, Miki [National Cardiovascular Center, Suita, Osaka (Japan)

    2002-01-01

    This study was done to assess the value of True FISP cine in patients with poor cardiac function. True FISP cine and FLASH cine imaging were performed on a 1.5 T machine. Both short axis and horizontal long axis imaging sections were used. The imaging sections used a Matrix (120 x 128), FOV (24 x 32 cm), and had a slice thickness of 8 mm. The imaging time for True FISP cine was 8 heart beats and 17 heart beats for FLASH cine. The contrast-to-noise ratio between the blood and myocardium (CNR) was measured at enddiastole and endsystole. The subjects in the study were 10 healty volunteers (average age 26.5{+-}3.2 years) and 12 patients with hypofunction (average age 53.9{+-}13.2 years). In the volunteers, the CNR of the short axis imaging was similar in both True FISP (24.6{+-}3.7) and FLASH (23.4{+-}5.9). In the patients with poor cardiac function however, the CNR of True FISP was larger than FLASH in both the short and long axis. In the short axis (22.7{+-}6.1 vs. 17.9{+-}5.3, P<0.01) and in the long axis (17.4{+-}4.3 vs. 9.3{+-}4.0, P<0.01). We conclude that True FISP cine has a higher contrast in a shorter imaging time than FLASH cine. True FISP cine is especially useful in patients with poor cardiac function. (author)

  10. The dynamic interplay between perceived true self-knowledge and decision satisfaction.

    Science.gov (United States)

    Schlegel, Rebecca J; Hicks, Joshua A; Davis, William E; Hirsch, Kelly A; Smith, Christina M

    2013-03-01

    The present research used multiple methods to examine the hypothesis that perceived true self-knowledge and decision satisfaction are inextricably linked together by a widely held "true-self-as-guide" lay theory of decision making. Consistent with this proposition, Study 1 found that participants rated using the true self as a guide as more important for achieving personal satisfaction than a variety of other potential decision-making strategies. After establishing the prevalence of this lay theory, the remaining studies then focused on examining the proposed consequent relationship between perceived true self-knowledge and decision satisfaction. Consistent with hypotheses, 2 cross-sectional correlational studies (Studies 2 and 3) found a positive relationship between perceived true self-knowledge and decision satisfaction for different types of major decisions. Study 4 used daily diary methods to demonstrate that fluctuations in perceived true self-knowledge reliably covary with fluctuations in decision satisfaction. Finally, 2 studies directly examined the causal direction of this relationship through experimental manipulation and revealed that the relationship is truly bidirectional. More specifically, Study 5 showed that manipulating perceived knowledge of the true self (but not other self-concepts) directly affects decision satisfaction. Study 6 showed that this effect also works in reverse by manipulating feelings of decision satisfaction, which directly affected perceived knowledge of the true self (but not other self-concepts). Taken together, these studies suggest that people believe the true self should be used as a guide when making major life decisions and that this belief has observable consequences for the self and decision making. PsycINFO Database Record (c) 2013 APA, all rights reserved

  11. From gender identity disorder to gender identity creativity: true gender self child therapy.

    Science.gov (United States)

    Ehrensaft, Diane

    2012-01-01

    True gender self child therapy is based on the premise of gender as a web that weaves together nature, nurture, and culture and allows for a myriad of healthy gender outcomes. This article presents concepts of true gender self, false gender self, and gender creativity as they operationalize in clinical work with children who need therapeutic supports to establish an authentic gender self while developing strategies for negotiating an environment resistant to that self. Categories of gender nonconforming children are outlined and excerpts of a treatment of a young transgender child are presented to illustrate true gender self child therapy.

  12. Construction of Chained True Score Equipercentile Equatings under the Kernel Equating (KE) Framework and Their Relationship to Levine True Score Equating. Research Report. ETS RR-09-24

    Science.gov (United States)

    Chen, Haiwen; Holland, Paul

    2009-01-01

    In this paper, we develop a new chained equipercentile equating procedure for the nonequivalent groups with anchor test (NEAT) design under the assumptions of the classical test theory model. This new equating is named chained true score equipercentile equating. We also apply the kernel equating framework to this equating design, resulting in a…

  13. Final report of the TRUE Block Scale project. 3. Modelling of flow and transport

    Energy Technology Data Exchange (ETDEWEB)

    Poteri, Antti [VTT Processes, Helsinki (Finland); Billaux, Daniel [Itasca Consultants SA, Ecully (France); Dershowitz, William [Golder Associates Inc., Redmond, WA (United States); Gomez-Hernandez, J. Jaime [Univ. Politecnica de Valencia (Spain). Dept. of Hydrahulic and Environmental Engineering; Cvetkovic, Vladimir [Royal Inst. of Tech., Stockholm (Sweden). Div. of Water Resources Engineering; Hautojaervi, Aimo [Posiva Oy, Olkiluoto (Finland); Holton, David [Serco Assurance, Harwell (United Kingdom); Medina, Agustin [UPC, Barcelona (Spain); Winberg, Anders (ed.) [Conterra AB, Uppsala (Sweden)

    2002-12-01

    A series of tracer experiments were performed as part of the TRUE Block Scale experiment over length scales ranging from 10 to 100 m. The in situ experimentation was preceded by a comprehensive iterative characterisation campaign - the results from one borehole was used to update descriptive models and provide the basis for continued characterisation. Apart from core drilling, various types of laboratory investigations, core logging, borehole TV imaging and various types of hydraulic tests (single hole and cross-hole) were performed. Based on the characterisation data a hydro structural model of the investigated rock volume was constructed including deterministic structures and a stochastic background fracture population, and their material properties. In addition, a generic microstructure conceptual model of the investigated structures was developed. Tracer tests with radioactive sorbing tracers performed in three flow paths were preceded by various pre-tests including tracer dilution tests, which were used to select suitable configurations of tracer injection and pumping in the established borehole array. The in situ experimentation was preceded by formulation of basic questions and associated hypotheses to be addressed by the tracer tests and the subsequent evaluation. The hypotheses included address of the validity of the hydro structural model, the effects of heterogeneity and block scale retention. Model predictions and subsequent evaluation modelling was performed using a wide variety of model concepts. These included stochastic continuum, discrete feature network and channel network models formulated in 3D, which also solved the flow problem. In addition, two 'single channel' approaches (Posiva Streamtube and LaSAR extended to the block scale) were employed. A common basis for transport was formulated. The difference between the approaches was found in how heterogeneity is accounted for, both in terms of number of different types of immobile zones

  14. Final report of the TRUE Block Scale project. 3. Modelling of flow and transport

    International Nuclear Information System (INIS)

    Poteri, Antti; Billaux, Daniel; Dershowitz, William; Gomez-Hernandez, J. Jaime; Holton, David; Medina, Agustin; Winberg, Anders

    2002-12-01

    A series of tracer experiments were performed as part of the TRUE Block Scale experiment over length scales ranging from 10 to 100 m. The in situ experimentation was preceded by a comprehensive iterative characterisation campaign - the results from one borehole was used to update descriptive models and provide the basis for continued characterisation. Apart from core drilling, various types of laboratory investigations, core logging, borehole TV imaging and various types of hydraulic tests (single hole and cross-hole) were performed. Based on the characterisation data a hydro structural model of the investigated rock volume was constructed including deterministic structures and a stochastic background fracture population, and their material properties. In addition, a generic microstructure conceptual model of the investigated structures was developed. Tracer tests with radioactive sorbing tracers performed in three flow paths were preceded by various pre-tests including tracer dilution tests, which were used to select suitable configurations of tracer injection and pumping in the established borehole array. The in situ experimentation was preceded by formulation of basic questions and associated hypotheses to be addressed by the tracer tests and the subsequent evaluation. The hypotheses included address of the validity of the hydro structural model, the effects of heterogeneity and block scale retention. Model predictions and subsequent evaluation modelling was performed using a wide variety of model concepts. These included stochastic continuum, discrete feature network and channel network models formulated in 3D, which also solved the flow problem. In addition, two 'single channel' approaches (Posiva Streamtube and LaSAR extended to the block scale) were employed. A common basis for transport was formulated. The difference between the approaches was found in how heterogeneity is accounted for, both in terms of number of different types of immobile zones included

  15. Molecular surveillance of true nontypeable Haemophilus influenzae: an evaluation of PCR screening assays.

    Science.gov (United States)

    Binks, Michael J; Temple, Beth; Kirkham, Lea-Ann; Wiertsema, Selma P; Dunne, Eileen M; Richmond, Peter C; Marsh, Robyn L; Leach, Amanda J; Smith-Vaughan, Heidi C

    2012-01-01

    Unambiguous identification of nontypeable Haemophilus influenzae (NTHi) is not possible by conventional microbiology. Molecular characterisation of phenotypically defined NTHi isolates suggests that up to 40% are Haemophilus haemolyticus (Hh); however, the genetic similarity of NTHi and Hh limits the power of simple molecular techniques such as PCR for species discrimination. Here we assess the ability of previously published and novel PCR-based assays to identify true NTHi. Sixty phenotypic NTHi isolates, classified by a dual 16S rRNA gene PCR algorithm as NTHi (n = 22), Hh (n = 27) or equivocal (n = 11), were further characterised by sequencing of the 16S rRNA and recA genes then interrogated by PCR-based assays targeting the omp P2, omp P6, lgtC, hpd, 16S rRNA, fucK and iga genes. The sequencing data and PCR results were used to define NTHi for this study. Two hpd real time PCR assays (hpd#1 and hpd#3) and the conventional iga PCR assay were equally efficient at differentiating study-defined NTHi from Hh, each with a receiver operator characteristic curve area of 0.90 [0.83; 0.98]. The hpd#1 and hpd#3 assays were completely specific against a panel of common respiratory bacteria, unlike the iga PCR, and the hpd#3 assay was able to detect below 10 copies per reaction. Our data suggest an evolutionary continuum between NTHi and Hh and therefore no single gene target could completely differentiate NTHi from Hh. The hpd#3 real time PCR assay proved to be the superior method for discrimination of NTHi from closely related Haemophilus species with the added potential for quantification of H. influenzae directly from specimens. We suggest the hpd#3 assay would be suitable for routine NTHi surveillance and to assess the impact of antibiotics and vaccines, on H. influenzae carriage rates, carriage density, and disease.

  16. Does the Sauerbrey equation hold true for binding of peptides and globular proteins to a QCM?

    Directory of Open Access Journals (Sweden)

    Jean E. Sohna Sohna

    2016-12-01

    Full Text Available The term ‘microbalance’ arose after Sauerbrey showed a mass per unit area dependence on sensor frequency change for thin, solid films on a QCM. Others have extrapolated this relationship to interactions with biological ‘soft’ matter using acoustic wave devices. We rigorously examined the relationship between QCM frequency change and the molecular weight of protein and peptide analytes on a RAP♦id 4™ system using more than 120 individual assays. A series of amino acid, peptides and proteins with molecular weight from 372 to 150,000 Da constituting a molecular weight ladder were biotinylated with a target biotin/protein ratio close to one to minimize avidity effects. Analyte concentration and contact time were chosen so as to attain near saturation of an anti-biotin antibody surface. The series resistance and resonant frequency changes (dF and dR arising from a 5-parameter fit of the imaginary component of the impedance signal were analysed, giving a linear relationship (R2 = 0.98 between frequency response and analyte molecular weight, even down to level of a single amino-acid. As predicted by theory, there was also a linear relationship between the changes in density and viscosity of the liquid in contact with the sensor and both dF and dR. The resistance and resonance frequency changes recorded for mixtures of deuterium oxide and glycerol were the sum of changes induced by each individual liquid. Hence the Sauerbrey equation for mass per unit area dependence of QCM signal does hold true for peptides and proteins in a liquid. Keywords: Calibration, Quartz crystal microbalance, Thickness shear mode, Biosensor, Microfluidics, Resonant acoustic profiling

  17. Simulations of pulsating one-dimensional detonations with true fifth order accuracy

    International Nuclear Information System (INIS)

    Henrick, Andrew K.; Aslam, Tariq D.; Powers, Joseph M.

    2006-01-01

    A novel, highly accurate numerical scheme based on shock-fitting coupled with fifth order spatial and temporal discretizations is applied to a classical unsteady detonation problem to generate solutions with unprecedented accuracy. The one-dimensional reactive Euler equations for a calorically perfect mixture of ideal gases whose reaction is described by single-step irreversible Arrhenius kinetics are solved in a series of calculations in which the activation energy is varied. In contrast with nearly all known simulations of this problem, which converge at a rate no greater than first order as the spatial and temporal grid is refined, the present method is shown to converge at a rate consistent with the fifth order accuracy of the spatial and temporal discretization schemes. This high accuracy enables more precise verification of known results and prediction of heretofore unknown phenomena. To five significant figures, the scheme faithfully recovers the stability boundary, growth rates, and wave-numbers predicted by an independent linear stability theory in the stable and weakly unstable regime. As the activation energy is increased, a series of period-doubling events are predicted, and the system undergoes a transition to chaos. Consistent with general theories of non-linear dynamics, the bifurcation points are seen to converge at a rate for which the Feigenbaum constant is 4.66 ± 0.09, in close agreement with the true value of 4.669201... As activation energy is increased further, domains are identified in which the system undergoes a transition from a chaotic state back to one whose limit cycles are characterized by a small number of non-linear oscillatory modes. This result is consistent with behavior of other non-linear dynamical systems, but not typically considered in detonation dynamics. The period and average detonation velocity are calculated for a variety of asymptotically stable limit cycles. The average velocity for such pulsating detonations is found

  18. Microplastic and macroplastic ingestion by a deep diving, oceanic cetacean: The True's beaked whale Mesoplodon mirus

    International Nuclear Information System (INIS)

    Lusher, Amy L.; Hernandez-Milian, Gema; O'Brien, Joanne; Berrow, Simon; O'Connor, Ian; Officer, Rick

    2015-01-01

    When mammals strand, they present a unique opportunity to obtain insights into their ecology. In May 2013, three True's beaked whales (two adult females and a female calf) stranded on the north and west coasts of Ireland and the contents of their stomachs and intestines were analysed for anthropogenic debris. A method for identifying microplastics ingested by larger marine organisms was developed. Microplastics were identified throughout the digestive tract of the single whale that was examined for the presence of microplastics. The two adult females had macroplastic items in their stomachs. Food remains recovered from the adult whales consisted of mesopelagic fish (Benthosema glaciale, Nansenia spp., Chauliodius sloani) and cephalopods, although trophic transfer has been discussed, it was not possible to ascertain whether prey were the source of microplastics. This is the first study to directly identify microplastics <5 mm in a cetacean species. - Highlights: • True's beaked whales stranded in Ireland were examined for anthropogenic debris. • One adult female had microplastics throughout her digestive tract. • Both adult females ingested macroplastic items. • Dietary analysis suggests the whales fed on mesopelagic fish. - Dietary study finds microplastic and macroplastic ingestion by rare, oceanic, predatory cetaceans stranded in Ireland

  19. Gross and true ileal digestible amino acid contents of several animal body proteins and their hydrolysates.

    Science.gov (United States)

    Cui, J; Chong, B; Rutherfurd, S M; Wilkinson, B; Singh, H; Moughan, P J

    2013-07-01

    Amino acid compositions of ovine muscle, ovine myofibrillar protein, ovine spleen, ovine liver, bovine blood plasma, bovine blood globulins and bovine serum albumin and the amino acid compositions and in vivo (laboratory rat) true ileal amino acid digestibilities of hydrolysates (sequential hydrolysis with Neutrase, Alcalase and Flavourzyme) of these protein sources were determined. True ileal amino acid digestibility differed (Pprotein hydrolysates. The ovine myofibrillar protein and liver hydrolysates were the most digestible, with a mean true ileal digestibility across all amino acids of 99%. The least digestible protein hydrolysate was bovine serum albumin with a comparable mean true ileal digestibility of 93%. When the digestible amino acid contents were expressed as proportions relative to lysine, considerable differences, across the diverse protein sources, were found in the pattern of predicted absorbed amino acids. Copyright © 2013 Elsevier Ltd. All rights reserved.

  20. Feeling like you know who you are: perceived true self-knowledge and meaning in life.

    Science.gov (United States)

    Schlegel, Rebecca J; Hicks, Joshua A; King, Laura A; Arndt, Jamie

    2011-06-01

    The essence of who a person really is has been labeled the "true self," and an emerging area of research suggests that this self-concept plays an important role in the creation of a fulfilling existence. Three studies investigate the role of the subjective feeling that one possesses knowledge of one's true self in meaning in life judgments. Consistently, the perception of availability of true self-knowledge (operationalized as the metacognitive experience of ease in describing one's true self) predicted meaning in life judgments over and above other potentially related constructs such as mood and self-esteem. Conversely, the subjective availability of knowledge of how one actually behaves (i.e., one's actual self) was unrelated to meaning in life judgments. Implications and directions for future research are discussed.

  1. On-line Learning of Unlearnable True Teacher through Mobile Ensemble Teachers

    Science.gov (United States)

    Hirama, Takeshi; Hukushima, Koji

    2008-09-01

    The on-line learning of a hierarchical learning model is studied by a method based on statistical mechanics. In our model, a student of a simple perceptron learns from not a true teacher directly, but ensemble teachers who learn from a true teacher with a perceptron learning rule. Since the true teacher and ensemble teachers are expressed as nonmonotonic and simple perceptrons, respectively, the ensemble teachers go around the unlearnable true teacher with the distance between them fixed in an asymptotic steady state. The generalization performance of the student is shown to exceed that of the ensemble teachers in a transient state, as was shown in similar ensemble-teachers models. Furthermore, it is found that moving the ensemble teachers even in the steady state, in contrast to the fixed ensemble teachers, is efficient for the performance of the student.

  2. A True Human Tail in a Neonate; Case report and literature review

    Directory of Open Access Journals (Sweden)

    Mahesh K. Pillai

    2017-03-01

    Full Text Available A true human tail is a benign vestigial caudal cutaneous structure composed of adipose, connective tissue, muscle, vessels, nerves and mechanoreceptors. A true human tail can be distinguished from a pseudotail as the latter is commonly associated with underlying spinal dysraphism, which requires specialised management. True human tails are very rare, with fewer than 40 cases reported to date. We report a healthy one-day-old male newborn who was referred to the Bharath Hospital, Kottayam, Kerala, India, in 2014 with a cutaneous appendage arising from the lumbosacral region. Magnetic resonance imaging of the spine ruled out spinal dysraphism. The appendage was removed by simple surgical excision. Clinicians should emphasise use of ‘true tail’ and ‘pseudotail’ as specific disparate terms as the clinical, radiological and histological findings of these conditions differ significantly, along with management strategies and outcomes.

  3. Arm-associated measurements as estimates of true height in black ...

    African Journals Online (AJOL)

    arm-associated measurements to true height included that of the World Health ... Conclusion: Findings indicate the need for gender and race-specific height estimation ..... New. York, NY: Springer; 2012. 12. Golshan M, Amra B, Hoghoghi MA.

  4. A true love story. Young people's romantic and sexual development in the context of everyday life

    Directory of Open Access Journals (Sweden)

    Henderien Steenbeek

    2017-06-01

    Full Text Available Wieke Dalenberg. A true love story. Young people’s romantic and sexual development in the context of everyday life. Groningen: University of Groningen, 2016, 147 p., ISBN 978 94 6332 100 6

  5. The cortical basis of true memory and false memory for motion.

    Science.gov (United States)

    Karanian, Jessica M; Slotnick, Scott D

    2014-02-01

    Behavioral evidence indicates that false memory, like true memory, can be rich in sensory detail. By contrast, there is fMRI evidence that true memory for visual information produces greater activity in earlier visual regions than false memory, which suggests true memory is associated with greater sensory detail. However, false memory in previous fMRI paradigms may have lacked sufficient sensory detail to recruit earlier visual processing regions. To investigate this possibility in the present fMRI study, we employed a paradigm that produced feature-specific false memory with a high degree of visual detail. During the encoding phase, moving or stationary abstract shapes were presented to the left or right of fixation. During the retrieval phase, shapes from encoding were presented at fixation and participants classified each item as previously "moving" or "stationary" within each visual field. Consistent with previous fMRI findings, true memory but not false memory for motion activated motion processing region MT+, while both true memory and false memory activated later cortical processing regions. In addition, false memory but not true memory for motion activated language processing regions. The present findings indicate that true memory activates earlier visual regions to a greater degree than false memory, even under conditions of detailed retrieval. Thus, the dissociation between previous behavioral findings and fMRI findings do not appear to be task dependent. Future work will be needed to assess whether the same pattern of true memory and false memory activity is observed for different sensory modalities. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. How Fuzzy-Trace Theory Predicts True and False Memories for Words, Sentences, and Narratives

    OpenAIRE

    Reyna, Valerie F.; Corbin, Jonathan C.; Weldon, Rebecca B.; Brainerd, Charles J.

    2016-01-01

    Fuzzy-trace theory posits independent verbatim and gist memory processes, a distinction that has implications for such applied topics as eyewitness testimony. This distinction between precise, literal verbatim memory and meaning-based, intuitive gist accounts for memory paradoxes including dissociations between true and false memory, false memories outlasting true memories, and developmental increases in false memory. We provide an overview of fuzzy-trace theory, and, using mathematical model...

  7. MODEL PENSKORAN PARTIAL CREDIT PADA BUTIR MULTIPLE TRUE-FALSE BIDANG FISIKA

    OpenAIRE

    Wasis Wasis

    2013-01-01

    Tujuan penelitian ini menghasilkan model penskoran politomus untuk respons butir multiple true-false, sehingga dapat mengestimasi secara lebih akurat kemampuan di bidang fisika. Pengembangan penskoran menggunakan Four-D model dan diuji akurasinya melalui penelitian empiris dan simulasi. Penelitian empiris menggunakan 15 butir multiple true-false yang diambil dari soal UMPTN tahun 1996-2006 dan dikenakan pada 410 mahasiswa baru FMIPA Universitas Negeri Surabaya angkatan tahun 2007. Respons pes...

  8. True Confessions.

    Science.gov (United States)

    Zielinski, Dave

    2001-01-01

    Four "virtual trainers" describe the challenges and successes of providing web-based training and give advice on planning coursework, timing instruction, distinguishing between skills training and information sharing, troubleshooting technology difficulties, and adapting to increased workload. (SK)

  9. True rewards

    Science.gov (United States)

    Friebele, Elaine

    The National Science Board invites nominations for the 1998 NSB Public Service Award. Candidates should meet at least one of the following criteria: increased understanding of science and engineering or encouraged others to do so; promoted the engagement of scientists and engineers in public outreach and scientific literacy; helped to develop broad science and engineering policy and its support; influenced and encouraged the next generation of scientists and engineers; achieved broad recognition outside area of specialization; and fostered awareness among broad segments of the population. The award may be given to one or more individuals, to a company, corporation, or organization, but not to members of the U.S. government.The deadline for nominations is July 31, 1997. Nominations must be accompanied by the addresses and telephone numbers of both the nominee and nominator, a summary of the nominee's activities, and the nominee's vitae (no more than three pages).

  10. Determination of true coincidence correction factors using Monte-Carlo simulation techniques

    Directory of Open Access Journals (Sweden)

    Chionis Dionysios A.

    2014-01-01

    Full Text Available Aim of this work is the numerical calculation of the true coincidence correction factors by means of Monte-Carlo simulation techniques. For this purpose, the Monte Carlo computer code PENELOPE was used and the main program PENMAIN was properly modified in order to include the effect of the true coincidence phenomenon. The modified main program that takes into consideration the true coincidence phenomenon was used for the full energy peak efficiency determination of an XtRa Ge detector with relative efficiency 104% and the results obtained for the 1173 keV and 1332 keV photons of 60Co were found consistent with respective experimental ones. The true coincidence correction factors were calculated as the ratio of the full energy peak efficiencies was determined from the original main program PENMAIN and the modified main program PENMAIN. The developed technique was applied for 57Co, 88Y, and 134Cs and for two source-to-detector geometries. The results obtained were compared with true coincidence correction factors calculated from the "TrueCoinc" program and the relative bias was found to be less than 2%, 4%, and 8% for 57Co, 88Y, and 134Cs, respectively.

  11. Accurate decisions in an uncertain world: collective cognition increases true positives while decreasing false positives.

    Science.gov (United States)

    Wolf, Max; Kurvers, Ralf H J M; Ward, Ashley J W; Krause, Stefan; Krause, Jens

    2013-04-07

    In a wide range of contexts, including predator avoidance, medical decision-making and security screening, decision accuracy is fundamentally constrained by the trade-off between true and false positives. Increased true positives are possible only at the cost of increased false positives; conversely, decreased false positives are associated with decreased true positives. We use an integrated theoretical and experimental approach to show that a group of decision-makers can overcome this basic limitation. Using a mathematical model, we show that a simple quorum decision rule enables individuals in groups to simultaneously increase true positives and decrease false positives. The results from a predator-detection experiment that we performed with humans are in line with these predictions: (i) after observing the choices of the other group members, individuals both increase true positives and decrease false positives, (ii) this effect gets stronger as group size increases, (iii) individuals use a quorum threshold set between the average true- and false-positive rates of the other group members, and (iv) individuals adjust their quorum adaptively to the performance of the group. Our results have broad implications for our understanding of the ecology and evolution of group-living animals and lend themselves for applications in the human domain such as the design of improved screening methods in medical, forensic, security and business applications.

  12. Control effects of stimulus paradigms on characteristic firings of parkinsonism

    Science.gov (United States)

    Zhang, Honghui; Wang, Qingyun; Chen, Guanrong

    2014-09-01

    Experimental studies have shown that neuron population located in the basal ganglia of parkinsonian primates can exhibit characteristic firings with certain firing rates differing from normal brain activities. Motivated by recent experimental findings, we investigate the effects of various stimulation paradigms on the firing rates of parkinsonism based on the proposed dynamical models. Our results show that the closed-loop deep brain stimulation is superior in ameliorating the firing behaviors of the parkinsonism, and other control strategies have similar effects according to the observation of electrophysiological experiments. In addition, in conformity to physiological experiments, we found that there exists optimal delay of input in the closed-loop GPtrain|M1 paradigm, where more normal behaviors can be obtained. More interestingly, we observed that W-shaped curves of the firing rates always appear as stimulus delay varies. We furthermore verify the robustness of the obtained results by studying three pallidal discharge rates of the parkinsonism based on the conductance-based model, as well as the integrate-and-fire-or-burst model. Finally, we show that short-term plasticity can improve the firing rates and optimize the control effects on parkinsonism. Our conclusions may give more theoretical insight into Parkinson's disease studies.

  13. True Orthophoto Generation from Aerial Frame Images and LiDAR Data: An Update

    Directory of Open Access Journals (Sweden)

    Hamid Gharibi

    2018-04-01

    Full Text Available Image spectral and Light Detection and Ranging (LiDAR positional information can be related through the orthophoto generation process. Orthophotos have a uniform scale and represent all objects in their correct planimetric locations. However, orthophotos generated using conventional methods suffer from an artifact known as the double-mapping effect that occurs in areas occluded by tall objects. The double-mapping problem can be resolved through the commonly known true orthophoto generation procedure, in which an occlusion detection process is incorporated. This paper presents a review of occlusion detection methods, from which three techniques are compared and analyzed using experimental results. The paper also describes a framework for true orthophoto production based on an angle-based occlusion detection method. To improve the performance of the angle-based technique, two modifications to this method are introduced. These modifications, which aim at resolving false visibilities reported within the angle-based occlusion detection process, are referred to as occlusion extension and radial section overlap. A weighted averaging approach is also proposed to mitigate the seamline effect and spectral dissimilarity that may appear in true orthophoto mosaics. Moreover, true orthophotos generated from high-resolution aerial images and high-density LiDAR data using the updated version of angle-based methodology are illustrated for two urban study areas. To investigate the potential of image matching techniques in producing true orthophotos and point clouds, a comparison between the LiDAR-based and image-matching-based true orthophotos and digital surface models (DSMs for an urban study area is also presented in this paper. Among the investigated occlusion detection methods, the angle-based technique demonstrated a better performance in terms of output and running time. The LiDAR-based true orthophotos and DSMs showed higher qualities compared to their

  14. Usefulness of true FISP cine MR imaging in patients with poor cardiac function

    International Nuclear Information System (INIS)

    Sakuma, Toshiharu; Yamada, Naoaki; Motooka, Makoto; Enomoto, Naoyuki; Maeshima, Isamu; Matsuda, Kazuhide; Urayama, Shinichi; Ikeo, Miki

    2002-01-01

    This study was done to assess the value of True FISP cine in patients with poor cardiac function. True FISP cine and FLASH cine imaging were performed on a 1.5 T machine. Both short axis and horizontal long axis imaging sections were used. The imaging sections used a Matrix (120 x 128), FOV (24 x 32 cm), and had a slice thickness of 8 mm. The imaging time for True FISP cine was 8 heart beats and 17 heart beats for FLASH cine. The contrast-to-noise ratio between the blood and myocardium (CNR) was measured at enddiastole and endsystole. The subjects in the study were 10 healty volunteers (average age 26.5±3.2 years) and 12 patients with hypofunction (average age 53.9±13.2 years). In the volunteers, the CNR of the short axis imaging was similar in both True FISP (24.6±3.7) and FLASH (23.4±5.9). In the patients with poor cardiac function however, the CNR of True FISP was larger than FLASH in both the short and long axis. In the short axis (22.7±6.1 vs. 17.9±5.3, P<0.01) and in the long axis (17.4±4.3 vs. 9.3±4.0, P<0.01). We conclude that True FISP cine has a higher contrast in a shorter imaging time than FLASH cine. True FISP cine is especially useful in patients with poor cardiac function. (author)

  15. Visualization of swallowing using real-time TrueFISP MR fluoroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Barkhausen, Joerg; Goyen, Mathias; Lauenstein, Thomas; Debatin, Joerg F. [Department of Diagnostic Radiology, University Hospital Essen (Germany); Winterfeld, F. von; Arweiler-Harbeck, Diana [Department of Otorhinolaryngology, University Hospital Essen (Germany)

    2002-01-01

    The aim of this study was to evaluate the ability of different real-time true fast imaging with steady precession (TrueFISP) sequences regarding their ability to depict the swallowing process and delineate oropharyngeal pathologies in patients with dysphagia. Real-time TrueFISP visualization of swallowing was performed in 8 volunteers and 6 patients with dysphagia using a 1.5 T scanner (Magnetom Sonata, Siemens, Erlangen Germany) equipped with high-performance gradients (amplitude 40 mT/m). Image quality of four different real-time TrueFISP sequences (TR 2.2-3.0 ms, TE 1.1-1.5 ms, matrix 63 x 128-135 x 256, field of view 250 mm{sup 2}, acquisition time per image 139-405 ms) was evaluated. Water, yoghurt, and semolina pudding were assessed as oral contrast agents. Functional exploration of the oropharyngeal apparatus was best possible using the fastest real-time TrueFISP sequence (TR 2.2 ms, TE 1.1 ms, matrix 63 x 128). Increased acquisition time resulted in blurring of anatomical structures. As the image contrast of TrueFISP sequences depends on T2/T1 properties, all tested foodstuff were well suited as oral contrast agents, but image quality was best using semolina pudding. Real-time visualization of swallowing is possible using real-time TrueFISP sequences in conjunction with oral contrast agents. For the functional exploration of swallowing high temporal resolution is more crucial than spatial resolution. (orig.)

  16. Dogs cannot bark: event-related brain responses to true and false negated statements as indicators of higher-order conscious processing.

    Science.gov (United States)

    Herbert, Cornelia; Kübler, Andrea

    2011-01-01

    The present study investigated event-related brain potentials elicited by true and false negated statements to evaluate if discrimination of the truth value of negated information relies on conscious processing and requires higher-order cognitive processing in healthy subjects across different levels of stimulus complexity. The stimulus material consisted of true and false negated sentences (sentence level) and prime-target expressions (word level). Stimuli were presented acoustically and no overt behavioral response of the participants was required. Event-related brain potentials to target words preceded by true and false negated expressions were analyzed both within group and at the single subject level. Across the different processing conditions (word pairs and sentences), target words elicited a frontal negativity and a late positivity in the time window from 600-1000 msec post target word onset. Amplitudes of both brain potentials varied as a function of the truth value of the negated expressions. Results were confirmed at the single-subject level. In sum, our results support recent suggestions according to which evaluation of the truth value of a negated expression is a time- and cognitively demanding process that cannot be solved automatically, and thus requires conscious processing. Our paradigm provides insight into higher-order processing related to language comprehension and reasoning in healthy subjects. Future studies are needed to evaluate if our paradigm also proves sensitive for the detection of consciousness in non-responsive patients.

  17. Dogs cannot bark: event-related brain responses to true and false negated statements as indicators of higher-order conscious processing.

    Directory of Open Access Journals (Sweden)

    Cornelia Herbert

    Full Text Available The present study investigated event-related brain potentials elicited by true and false negated statements to evaluate if discrimination of the truth value of negated information relies on conscious processing and requires higher-order cognitive processing in healthy subjects across different levels of stimulus complexity. The stimulus material consisted of true and false negated sentences (sentence level and prime-target expressions (word level. Stimuli were presented acoustically and no overt behavioral response of the participants was required. Event-related brain potentials to target words preceded by true and false negated expressions were analyzed both within group and at the single subject level. Across the different processing conditions (word pairs and sentences, target words elicited a frontal negativity and a late positivity in the time window from 600-1000 msec post target word onset. Amplitudes of both brain potentials varied as a function of the truth value of the negated expressions. Results were confirmed at the single-subject level. In sum, our results support recent suggestions according to which evaluation of the truth value of a negated expression is a time- and cognitively demanding process that cannot be solved automatically, and thus requires conscious processing. Our paradigm provides insight into higher-order processing related to language comprehension and reasoning in healthy subjects. Future studies are needed to evaluate if our paradigm also proves sensitive for the detection of consciousness in non-responsive patients.

  18. Chemical composition, true nutrient digestibility, and true metabolizable energy of novel pet food protein sources using the precision-fed cecectomized rooster assay.

    Science.gov (United States)

    Deng, P; Utterback, P L; Parsons, C M; Hancock, L; Swanson, K S

    2016-08-01

    A wide variety of animal protein-based ingredients is commonly used in the pet food products. The raw ingredients and processing procedures used may greatly affect protein quality. Testing the quality of alternative protein sources is necessary and contributes to the sustainability of pet foods. The objective of this study was to test the chemical composition of 8 protein sources intended for use in dog and cat foods (calamari meal, pork peptone, alligator meal, lamb meal, venison meal, chicken meal, and 2 duck meals), and evaluate their true nutrient digestibility and nitrogen-corrected true ME (TMEn) using the precision-fed cecectomized rooster assay. Calamari meal and pork peptone had lower ash (4.4 and 3.6% of DM, respectively) but greater CP (88.1 and 80.5% of DM, respectively) and either greater or similar GE (5.6 and 5.3 kcal/g of DM, respectively) compared with alligator, lamb, venison, chicken, and duck meals (11.8 to 24.5% ash, 58.7 to 65.9% CP, and 4.6 to 5.3 kcal GE/g). Acid-hydrolyzed fat (AHF) was lower in calamari meal (8.7% of DM) compared with the other proteins tested (15.5-22.1% of DM). True nutrient digestibility was variable among the protein sources (52 to 79% of DM, 60 to 83% of OM, 78 to 92% of AHF, and 70 to 89% of GE) with pork peptone having the highest DM, AHF, and GE digestibility and calamari meal having the highest OM digestibility. True indispensable AA digestibility was highest for calamari meal, with all AA having a digestibility greater than 90%. Except for histidine, all indispensable AA had a digestibility over 85% for pork peptone. In contrast, true indispensable AA digestibility was lowest for lamb meal, with histidine having digestibility less than 70% and the other entire indispensable AA having digestibility between 72 and 88%. The TMEn of calamari meal (4.82 kcal/g DM and 86.9% of GE) was greater ( digestibility among protein sources intended for use in dog and cat foods and justifies further in vivo testing of novel

  19. Semantic processes leading to true and false memory formation in schizophrenia.

    Science.gov (United States)

    Paz-Alonso, Pedro M; Ghetti, Simona; Ramsay, Ian; Solomon, Marjorie; Yoon, Jong; Carter, Cameron S; Ragland, J Daniel

    2013-07-01

    Encoding semantic relationships between items on word lists (semantic processing) enhances true memories, but also increases memory distortions. Episodic memory impairments in schizophrenia (SZ) are strongly driven by failures to process semantic relations, but the exact nature of these relational semantic processing deficits is not well understood. Here, we used a false memory paradigm to investigate the impact of implicit and explicit semantic processing manipulations on episodic memory in SZ. Thirty SZ and 30 demographically matched healthy controls (HC) studied Deese/Roediger-McDermott (DRM) lists of semantically associated words. Half of the lists had strong implicit semantic associations and the remainder had low strength associations. Similarly, half of the lists were presented under "standard" instructions and the other half under explicit "relational processing" instructions. After study, participants performed recall and old/new recognition tests composed of targets, critical lures, and unrelated lures. HC exhibited higher true memories and better discriminability between true and false memory compared to SZ. High, versus low, associative strength increased false memory rates in both groups. However, explicit "relational processing" instructions positively improved true memory rates only in HC. Finally, true and false memory rates were associated with severity of disorganized and negative symptoms in SZ. These results suggest that reduced processing of semantic relationships during encoding in SZ may stem from an inability to implement explicit relational processing strategies rather than a fundamental deficit in the implicit activation and retrieval of word meanings from patients' semantic lexicon. Copyright © 2013 Elsevier B.V. All rights reserved.

  20. Emotional content enhances true but not false memory for categorized stimuli.

    Science.gov (United States)

    Choi, Hae-Yoon; Kensinger, Elizabeth A; Rajaram, Suparna

    2013-04-01

    Past research has shown that emotion enhances true memory, but that emotion can either increase or decrease false memory. Two theoretical possibilities-the distinctiveness of emotional stimuli and the conceptual relatedness of emotional content-have been implicated as being responsible for influencing both true and false memory for emotional content. In the present study, we sought to identify the mechanisms that underlie these mixed findings by equating the thematic relatedness of the study materials across each type of valence used (negative, positive, or neutral). In three experiments, categorically bound stimuli (e.g., funeral, pets, and office items) were used for this purpose. When the encoding task required the processing of thematic relatedness, a significant true-memory enhancement for emotional content emerged in recognition memory, but no emotional boost to false memory (exp. 1). This pattern persisted for true memory with a longer retention interval between study and test (24 h), and false recognition was reduced for emotional items (exp. 2). Finally, better recognition memory for emotional items once again emerged when the encoding task (arousal ratings) required the processing of the emotional aspect of the study items, with no emotional boost to false recognition (EXP. 3). Together, these findings suggest that when emotional and neutral stimuli are equivalently high in thematic relatedness, emotion continues to improve true memory, but it does not override other types of grouping to increase false memory.

  1. Dose dependence of true stress parameters in irradiated bcc, fcc, and hcp metals

    Science.gov (United States)

    Byun, T. S.

    2007-04-01

    The dose dependence of true stress parameters has been investigated for nuclear structural materials: A533B pressure vessel steels, modified 9Cr-1Mo and 9Cr-2WVTa ferritic martensitic steels, 316 and 316LN stainless steels, and Zircaloy-4. After irradiation to significant doses, these alloys show radiation-induced strengthening and often experience prompt necking at yield followed by large necking deformation. In the present work, the critical true stresses for deformation and fracture events, such as yield stress (YS), plastic instability stress (PIS), and true fracture stress (FS), were obtained from uniaxial tensile tests or calculated using a linear strain-hardening model for necking deformation. At low dose levels where no significant embrittlement was detected, the true fracture stress was nearly independent of dose. The plastic instability stress was also independent of dose before the critical dose-to-prompt-necking at yield was reached. A few bcc alloys such as ferritic martensitic steels experienced significant embrittlement at doses above ∼1 dpa; and the true fracture stress decreased with dose. The materials fractured before yield at or above 10 dpa.

  2. Visualising Three Dimensional Damage and Failure Envelopes: Implications for True Triaxial Deformation

    Science.gov (United States)

    Harland, S. R.; Browning, J.; Healy, D.; Meredith, P. G.; Mitchell, T. M.

    2017-12-01

    Ultimate failure in brittle rocks is commonly accepted to occur as a coalescence of micro-crack damage into a single failure plane. The geometry and evolution with stress of the cracks (damage) within the medium will play a role in dictating the geometry of the ultimate failure plane. Currently, the majority of experimental studies investigating damage evolution and rock failure use conventional triaxial stress states (σ1 > σ2 = σ3). Results from these tests can easily be represented on a Mohr-Coulomb plot (σn - τ), conveniently allowing the user to determine the geometry of the resultant failure plane. In reality however, stress in the subsurface is generally truly triaxial (σ1 > σ2 > σ3) and in this case, the Mohr-Coulomb failure criterion is inadequate as it incorporates no dependence on the intermediate stress (σ2), which has been shown to play an important role in controlling failure. It has recently been shown that differential stress is the key driver in initiating crack growth, regardless of the mean stress. Polyaxial failure criteria that incorporate the effect of the intermediate stress do exist and include the Modified Lade, Modified Wiebols and Cook, and the Drucker-Prager criteria. However, unlike the Mohr-Coulomb failure criterion, these polyaxial criteria do not offer any prediction of, or insight into, the geometry of the resultant failure plane. An additional downfall of all of the common conventional and polyaxial failure criteria is that they fail to describe the geometry of the damage (i.e. pre-failure microcracking) envelope with progressive stress; it is commonly assumed that the damage envelope is parallel to the ultimate brittle failure envelope. Here we use previously published polyaxial failure data for the Shirahama sandstone and Westerley granite to illustrate that the commonly used Mohr-Coulomb and polyaxial failure criteria do not sufficiently describe or capture failure or damage envelopes under true triaxial stress states

  3. Experimental validation of a true-scale morphing flap for large civil aircraft applications

    Science.gov (United States)

    Pecora, R.; Amoroso, F.; Arena, M.; Noviello, M. C.; Rea, F.

    2017-04-01

    Within the framework of the JTI-Clean Sky (CS) project, and during the first phase of the Low Noise Configuration Domain of the Green Regional Aircraft - Integrated Technological Demonstration (GRA-ITD, the preliminary design and technological demonstration of a novel wing flap architecture were addressed. Research activities were carried out to substantiate the feasibility of morphing concepts enabling flap camber variation in compliance with the demanding safety requirements applicable to the next generation green regional aircraft, 130- seats with open rotor configuration. The driving motivation for the investigation on such a technology was found in the opportunity to replace a conventional double slotted flap with a single slotted camber-morphing flap assuring similar high lift performances -in terms of maximum attainable lift coefficient and stall angle- while lowering emitted noise and system complexity. Studies and tests were limited to a portion of the flap element obtained by slicing the actual flap geometry with two cutting planes distant 0.8 meters along the wing span. Further activities were then addressed in order to increase the TRL of the validated architecture within the second phase of the CS-GRA. Relying upon the already assessed concept, an innovative and more advanced flap device was designed in order to enable two different morphing modes on the basis of the A/C flight condition / flap setting: Mode1, Overall camber morphing to enhance high-lift performances during take-off and landing (flap deployed); Mode2, Tab-like morphing mode. Upwards and downwards deflection of the flap tip during cruise (flap stowed) for load control at high speed. A true-scale segment of the outer wing flap (4 meters span with a mean chord of 0.9 meters) was selected as investigation domain for the new architecture in order to duly face the challenges posed by real wing installation. Advanced and innovative solutions for the adaptive structure, actuation and control

  4. Molecular surveillance of true nontypeable Haemophilus influenzae: an evaluation of PCR screening assays.

    Directory of Open Access Journals (Sweden)

    Michael J Binks

    Full Text Available BACKGROUND: Unambiguous identification of nontypeable Haemophilus influenzae (NTHi is not possible by conventional microbiology. Molecular characterisation of phenotypically defined NTHi isolates suggests that up to 40% are Haemophilus haemolyticus (Hh; however, the genetic similarity of NTHi and Hh limits the power of simple molecular techniques such as PCR for species discrimination. METHODOLOGY/PRINCIPAL FINDINGS: Here we assess the ability of previously published and novel PCR-based assays to identify true NTHi. Sixty phenotypic NTHi isolates, classified by a dual 16S rRNA gene PCR algorithm as NTHi (n = 22, Hh (n = 27 or equivocal (n = 11, were further characterised by sequencing of the 16S rRNA and recA genes then interrogated by PCR-based assays targeting the omp P2, omp P6, lgtC, hpd, 16S rRNA, fucK and iga genes. The sequencing data and PCR results were used to define NTHi for this study. Two hpd real time PCR assays (hpd#1 and hpd#3 and the conventional iga PCR assay were equally efficient at differentiating study-defined NTHi from Hh, each with a receiver operator characteristic curve area of 0.90 [0.83; 0.98]. The hpd#1 and hpd#3 assays were completely specific against a panel of common respiratory bacteria, unlike the iga PCR, and the hpd#3 assay was able to detect below 10 copies per reaction. CONCLUSIONS/SIGNIFICANCE: Our data suggest an evolutionary continuum between NTHi and Hh and therefore no single gene target could completely differentiate NTHi from Hh. The hpd#3 real time PCR assay proved to be the superior method for discrimination of NTHi from closely related Haemophilus species with the added potential for quantification of H. influenzae directly from specimens. We suggest the hpd#3 assay would be suitable for routine NTHi surveillance and to assess the impact of antibiotics and vaccines, on H. influenzae carriage rates, carriage density, and disease.

  5. Studies on the occurrence of true spiders as natural enemies in many Egyptian fields

    Directory of Open Access Journals (Sweden)

    Amira A. Ibrahim

    2012-01-01

    Full Text Available True spiders represent one of the most important natural predatory species in Egyptian fields. In this work, common true spiders were surveyed in wheat, cotton and maize fields, and were counted weekly by using the direct method. For evaluating the feeding consumption of true spiders, five feeding cases were tested (as preys. These cases were: eggs of Ephestia kuehniella, eggs of Phthorimaea operculella, one day eggs and larvae of E. kuehniella, larvae of E. kuehniella and P. operculella and larvae of E. kuehniella only. Results obtained revealed that, the highest average daily consumption for each spider was recorded in case of feeding on eggs of P. operculella. While, the longest survival period was recorded in case of feeding on larvae of E. kuehniella.

  6. Median Hetero-Associative Memories Applied to the Categorization of True-Color Patterns

    Science.gov (United States)

    Vázquez, Roberto A.; Sossa, Humberto

    Median associative memories (MED-AMs) are a special type of associative memory based on the median operator. This type of associative model has been applied to the restoration of gray scale images and provides better performance than other models, such as morphological associative memories, when the patterns are altered with mixed noise. Despite of his power, MED-AMs have not been applied in problems involving true-color patterns. In this paper we describe how a median hetero-associative memory (MED-HAM) could be applied in problems that involve true-color patterns. A complete study of the behavior of this associative model in the restoration of true-color images is performed using a benchmark of 14400 images altered by different type of noises. Furthermore, we describe how this model can be applied to an image categorization problem.

  7. False memory for context and true memory for context similarly activate the parahippocampal cortex.

    Science.gov (United States)

    Karanian, Jessica M; Slotnick, Scott D

    2017-06-01

    The role of the parahippocampal cortex is currently a topic of debate. One view posits that the parahippocampal cortex specifically processes spatial layouts and sensory details (i.e., the visual-spatial processing view). In contrast, the other view posits that the parahippocampal cortex more generally processes spatial and non-spatial contexts (i.e., the general contextual processing view). A large number of studies have found that true memories activate the parahippocampal cortex to a greater degree than false memories, which would appear to support the visual-spatial processing view as true memories are typically associated with greater visual-spatial detail than false memories. However, in previous studies, contextual details were also greater for true memories than false memories. Thus, such differential activity in the parahippocampal cortex may have reflected differences in contextual processing, which would challenge the visual-spatial processing view. In the present functional magnetic resonance imaging (fMRI) study, we employed a source memory paradigm to investigate the functional role of the parahippocampal cortex during true memory and false memory for contextual information to distinguish between the visual-spatial processing view and the general contextual processing view. During encoding, abstract shapes were presented to the left or right of fixation. During retrieval, old shapes were presented at fixation and participants indicated whether each shape was previously on the "left" or "right" followed by an "unsure", "sure", or "very sure" confidence rating. The conjunction of confident true memories for context and confident false memories for context produced activity in the parahippocampal cortex, which indicates that this region is associated with contextual processing. Furthermore, the direct contrast of true memory and false memory produced activity in the visual cortex but did not produce activity in the parahippocampal cortex. The present

  8. single crystals

    Indian Academy of Sciences (India)

    2018-05-18

    May 18, 2018 ... Abstract. 4-Nitrobenzoic acid (4-NBA) single crystals were studied for their linear and nonlinear optical ... studies on the proper growth, linear and nonlinear optical ..... between the optic axes and optic sign of the biaxial crystal.

  9. Myocardial imaging with thallium-201: an experimental model for analysis of the true myocardial and background image components

    International Nuclear Information System (INIS)

    Narahara, K.A.; Hamilton, G.W.; Williams, D.L.; Gould, K.L.

    1977-01-01

    The true myocardial and background components of a resting thallium-201 myocardial image were determined in an experimental dog model. True background was determined by imaging after the heart had been removed and replaced with a water-filled balloon of equal size and shape. In all studies, the background estimated from the region surrounding the heart exceeded true background activity. Furthermore, the relationship between true myocardial background and that estimated from the pericardiac region was inconsistent. Background estimates based on the activity surrounding the heart were not accurate predictors of true background activity

  10. Operational implications of accepting and denying whether a true value of risk exists

    DEFF Research Database (Denmark)

    Kozin, Igor

    It is suggested to look on probabilistic risk quantities and concepts through the prism of accepting one of the views: whether a true value of risk exists or not. It will be argued that discussions until now have been primarily focused on closely related topics that are different from the suggested...... one. In general, the values of risks are not known precisely and the analyst has the option to consider that convergence to a precise value of risk is possible in the limit. That is, the true value exists but due to limited time, resources or other limitations in assessing probabilities...

  11. True stress control asymmetric cyclic plastic behavior in SA333 C-Mn steel

    International Nuclear Information System (INIS)

    Paul, Surajit Kumar; Sivaprasad, S.; Dhar, S.; Tarafder, S.

    2010-01-01

    Asymmetric cyclic loading in the plastic region can leads to progressive accumulation of permanent strain. True stress controlled uniaxial asymmetric cycling on SA333 steel is conducted at various combinations of mean stress and stress amplitude in laboratory environment. It is investigated that fatigue life increases in the presence of mean stress. Plastic strain amplitude and hysteresis loop area are found to decrease with increasing mean stress. A huge difference of life and ratcheting strain accumulation is found in engineering and true stress controlled tests.

  12. Evaluation of electronic stability control effectiveness in Australasia.

    Science.gov (United States)

    Scully, Jim; Newstead, Stuart

    2008-11-01

    Electronic stability control (ESC) is an in-vehicle technology aimed at improving primary safety by assisting the driver in avoiding loss of control of the vehicle. The aim of this study was to use available crash data from Australia and New Zealand to evaluate the effectiveness of ESC in reducing crash risk and to establish whether benefits estimated from overseas studies have translated to the Australian and New Zealand environments. The sample analysed included 7699 crashed vehicles fitted with ESC which comprised of 90 different models. Poisson regression was used to test whether the differences in the observed and expected crash counts for ESC fitted vehicles were significant, with exposure being induced from counts of rear end impacts. It was found that ESC reduced the risk of single vehicle crashes in which the driver was injured by 68% for 4WDs compared with 27% for passenger cars. The effect of ESC on multiple vehicle crashes in Australia and New Zealand was not clear. The long-term benefits of fitting ESC to all vehicles in Australia were also investigated based on the estimated single vehicle crash reductions.

  13. Standardization of the TRUE Test imidazolidinyl urea and diazolidinyl urea patches

    DEFF Research Database (Denmark)

    Agner, T; Andersen, Klaus Ejner; Björkner, B

    2001-01-01

    The preservatives imidazolidinyl urea (IMID, Germall 115) and diazolidinyl urea (DU, Germall II) are commonly used in cosmetic products and are well-known sensitizers. The aim of the present study was to establish the optimal patch test concentration in hydrophilic dried-in vehicle (TRUE Test...

  14. True versus perturbed forest inventory plot locations for modeling: a simulation study

    Science.gov (United States)

    John W. Coulston; Kurt H. Riitters; Ronald E. McRoberts; William D. Smith

    2006-01-01

    USDA Forest Service Forest Inventory and Analysis plot information is widely used for timber inventories, forest health assessments, and environmental risk analyses. With few exceptions, true plot locations are not revealed; the plot coordinates are manipulated to obscure the location of field plots and thereby preserve plot integrity. The influence of perturbed plot...

  15. Radiation fibrosis : differentiation from true hilar mass on plain chest film

    International Nuclear Information System (INIS)

    Baik, Jun Hyun; Ahn, Kook Jin; Park, Seog Hee; Shinn, Kyung Sub

    1996-01-01

    Radiation-induced fibrotic mass might masquerade as a true hilar tumor mass on a plain chest radiograph. We attempted to differentiate radiation fibrosis from a true hilar tumor using only a plain radiograph. Plain chest radiographs were obtained from seven patients who had developed radiation fibrosis simulating hilar mass after radiation therapy for lung cancer, and from 19 patients with lung cancer, a comparison group, who had not received radiation therapy. They were reviewed for the obliteration of the overlapped mediastinal and hilar anatomical silhouettes by the mass : pulmonary artery, heart or aorta border, and paraspinal line. All seven patients with radiation-induced fibrotic mass(bilateral lesion in two patients) showed obliteration of all three overlapped anatomical silhouettes of the mediastinum and hilum on chest radiographs. In the comparison group of 19 patients with a true hilar mass, there was, however, no case which demonstrated obliteration of all landmarks, Obliteration of all anatomical landmarks at the hilum and mediastinum may be a helpful clue in the differential diagnosis of radiation-induced fibrotic mass from true hilar mass on a plain radiograph, particularly when clinical information on previous radiation therapy is unavailable

  16. Can Maltreated Children Inhibit True and False Memories for Emotional Information?

    Science.gov (United States)

    Howe, Mark L.; Toth, Sheree L.; Cicchetti, Dante

    2011-01-01

    The authors examined 284 maltreated and nonmaltreated children's (6- to 12-year-olds) ability to inhibit true and false memories for neutral and emotional information using the Deese/Roediger-McDermott (DRM) paradigm. Children studied either emotional or neutral DRM lists in a control condition or were given directed-remembering or…

  17. A Qualitative Assessment of the My True Body Bariatric Surgery Preparation Program

    Science.gov (United States)

    Nakamura, Tracy; Mamary, Edward

    2013-01-01

    Background: The My True Body (MTB) group intervention incorporates cognitive restructuring and social support into bariatric surgery preparation. Purpose: To identify and describe program components that support long-term behavioral modifications and influence confidence in healthy weight maintenance. Methods: Semistructured telephone interviews…

  18. Robust Scale Transformation Methods in IRT True Score Equating under Common-Item Nonequivalent Groups Design

    Science.gov (United States)

    He, Yong

    2013-01-01

    Common test items play an important role in equating multiple test forms under the common-item nonequivalent groups design. Inconsistent item parameter estimates among common items can lead to large bias in equated scores for IRT true score equating. Current methods extensively focus on detection and elimination of outlying common items, which…

  19. 3D laser imaging for ODOT interstate network at true 1-mm resolution.

    Science.gov (United States)

    2014-12-01

    With the development of 3D laser imaging technology, the latest iteration of : PaveVision3D Ultra can obtain true 1mm resolution 3D data at full-lane coverage in all : three directions at highway speed up to 60MPH. This project provides rapid survey ...

  20. True ileal amino acid digestibility of goat and cow milk infant formulas

    NARCIS (Netherlands)

    Rutherfurd, S.M.; Darragh, A.J.; Hendriks, W.H.; Prosser, C.G.; Lowry, D.

    2006-01-01

    Goat milk is used as an alternative to cow milk for the production of infant formulas. However, little is known about the protein quality and, specifically, about the digestible AA pattern of goat milk formulas compared with their cow milk counterparts. In this study, the true ileal AA digestibility

  1. The Development of Automatic and Controlled Inhibitory Retrieval Processes in True and False Recall

    Science.gov (United States)

    Knott, Lauren M.; Howe, Mark L.; Wimmer, Marina C.; Dewhurst, Stephen A.

    2011-01-01

    In three experiments, we investigated the role of automatic and controlled inhibitory retrieval processes in true and false memory development in children and adults. Experiment 1 incorporated a directed forgetting task to examine controlled retrieval inhibition. Experiments 2 and 3 used a part-set cue and retrieval practice task to examine…

  2. An Evaluation of the MMPI-2 and MMPI-A True Response Inconsistency (TRIN) Scales

    Science.gov (United States)

    Handel, Richard W.; Arnau, Randolph C.; Archer, Robert P.; Dandy, Kristina L.

    2006-01-01

    The Minnesota Multiphasic Personality Inventory--Adolescent (MMPI-A) and Minnesota Multiphasic Personality Inventory--2 (MMPI-2) True Response Inconsistency (TRIN) scales are measures of acquiescence and nonacquiescence included among the standard validity scales on these instruments. The goals of this study were to evaluate the effectiveness of…

  3. True Triaxial Strength and Failure Modes of Cubic Rock Specimens with Unloading the Minor Principal Stress

    Science.gov (United States)

    Li, Xibing; Du, Kun; Li, Diyuan

    2015-11-01

    True triaxial tests have been carried out on granite, sandstone and cement mortar using cubic specimens with the process of unloading the minor principal stress. The strengths and failure modes of the three rock materials are studied in the processes of unloading σ 3 and loading σ 1 by the newly developed true triaxial test system under different σ 2, aiming to study the mechanical responses of the rock in underground excavation at depth. It shows that the rock strength increases with the raising of the intermediate principal stress σ 2 when σ 3 is unloaded to zero. The true triaxial strength criterion by the power-law relationship can be used to fit the testing data. The "best-fitting" material parameters A and n ( A > 1.4 and n plastic deformation. The maximum extension strain criterion Stacey (Int J Rock Mech Min Sci Geomech Abstr 651 18(6):469-474, 1981) can be used to explain the change of failure mode from shear to slabbing for strong and hard rocks under true triaxial unloading test condition.

  4. Are relations in thesauri "context-free, definitional, and true in all possible worlds"?

    DEFF Research Database (Denmark)

    Hjørland, Birger

    2015-01-01

    Much of the literature of information science and knowledge organization has accepted and built upon Elaine Svenonius’ (2004) claim that “paradigmatic relationships are those that are context-free, definitional, and true in all possible worlds” (p. 583). At the same time, the literature...

  5. Classification of EC 3.1.1.3 bacterial true lipases using phylogenetic ...

    African Journals Online (AJOL)

    To obtain an overview of this industrially and very important class of enzymes and their characteristics, we collected and classified bacterial lipases sequences available from protein databases. Here we proposed an updated and revised classification of family I bacterial "true" lipases based mainly on a comparison of their ...

  6. Confidence Intervals for True Scores Using the Skew-Normal Distribution

    Science.gov (United States)

    Garcia-Perez, Miguel A.

    2010-01-01

    A recent comparative analysis of alternative interval estimation approaches and procedures has shown that confidence intervals (CIs) for true raw scores determined with the Score method--which uses the normal approximation to the binomial distribution--have actual coverage probabilities that are closest to their nominal level. It has also recently…

  7. Searching for the true diet of marine predators: incorporating Bayesian priors into stable isotope mixing models.

    Directory of Open Access Journals (Sweden)

    André Chiaradia

    Full Text Available Reconstructing the diet of top marine predators is of great significance in several key areas of applied ecology, requiring accurate estimation of their true diet. However, from conventional stomach content analysis to recent stable isotope and DNA analyses, no one method is bias or error free. Here, we evaluated the accuracy of recent methods to estimate the actual proportion of a controlled diet fed to a top-predator seabird, the Little penguin (Eudyptula minor. We combined published DNA data of penguins scats with blood plasma δ(15N and δ(13C values to reconstruct the diet of individual penguins fed experimentally. Mismatch between controlled (true ingested diet and dietary estimates obtained through the separately use of stable isotope and DNA data suggested some degree of differences in prey assimilation (stable isotope and digestion rates (DNA analysis. In contrast, combined posterior isotope mixing model with DNA Bayesian priors provided the closest match to the true diet. We provided the first evidence suggesting that the combined use of these complementary techniques may provide better estimates of the actual diet of top marine predators- a powerful tool in applied ecology in the search for the true consumed diet.

  8. Multigene molecular phylogenetics reveals true morels (Morchella) are especially species-rich in China

    Science.gov (United States)

    The phylogenetic diversity of true morels (Morchella) in China was estimated by initially analyzing nuclear ribosomal internal transcribed spacer (ITS) rDNA sequences from 361 specimens collected in 21 provinces during the 2003-2011 growing seasons, together with six collections obtained on loan fro...

  9. How well do ITS rDNA sequences differentiate species of true morels (Morchella)?

    Science.gov (United States)

    Arguably more mycophiles hunt true morels (Morchella) during their brief fruiting season each spring in the Northern Hemisphere than any other wild edible fungus. Concerns about overharvesting by individual collectors and commercial enterprises make it essential that science-based management practic...

  10. A preliminary assessment of the true morels (Morchella) in Newfoundland and Labrador

    Science.gov (United States)

    A preliminary assessment of true morels (Morchella) from Newfoundland and Labrador (NL) was obtained by using DNA sequence data from portions of three genes to identify 20 collections from Newfoundland and one from a remote location in Labrador. To place this work in a broader context, data on 25 co...

  11. Coarsening and pattern formation during true morphological phase separation in unstable thin films under gravity

    Science.gov (United States)

    Kumar, Avanish; Narayanam, Chaitanya; Khanna, Rajesh; Puri, Sanjay

    2017-12-01

    We address in detail the problem of true morphological phase separation (MPS) in three-dimensional or (2 +1 )-dimensional unstable thin liquid films (>100 nm) under the influence of gravity. The free-energy functionals of these films are asymmetric and show two points of common tangency, which facilitates the formation of two equilibrium phases. Three distinct patterns formed by relative preponderance of these phases are clearly identified in "true MPS". Asymmetricity induces two different pathways of pattern formation, viz., defect and direct pathway for true MPS. The pattern formation and phase-ordering dynamics have been studied using statistical measures such as structure factor, correlation function, and growth laws. In the late stage of coarsening, the system reaches into a scaling regime for both pathways, and the characteristic domain size follows the Lifshitz-Slyozov growth law [L (t ) ˜t1 /3] . However, for the defect pathway, there is a crossover of domain growth behavior from L (t ) ˜t1 /4→t1 /3 in the dynamical scaling regime. We also underline the analogies and differences behind the mechanisms of MPS and true MPS in thin liquid films and generic spinodal phase separation in binary mixtures.

  12. Asymptotic Standard Errors for Item Response Theory True Score Equating of Polytomous Items

    Science.gov (United States)

    Cher Wong, Cheow

    2015-01-01

    Building on previous works by Lord and Ogasawara for dichotomous items, this article proposes an approach to derive the asymptotic standard errors of item response theory true score equating involving polytomous items, for equivalent and nonequivalent groups of examinees. This analytical approach could be used in place of empirical methods like…

  13. its absence) in both his paintings and in his prison memoir, The True ...

    African Journals Online (AJOL)

    2016-04-08

    Apr 8, 2016 ... its absence) in both his paintings and in his prison memoir, The True Confessions of an Albino Terrorist (1984). While Saayman makes a promis- ing case for an oeuvre-wide reading of. Breytenbach's creative output, her own reading lacks depth and insight. Whereas the book argues that different genres ...

  14. Three-dimensional true FISP for high-resolution imaging of the whole brain

    International Nuclear Information System (INIS)

    Schmitz, B.; Hagen, T.; Reith, W.

    2003-01-01

    While high-resolution T1-weighted sequences, such as three-dimensional magnetization-prepared rapid gradient-echo imaging, are widely available, there is a lack of an equivalent fast high-resolution sequence providing T2 contrast. Using fast high-performance gradient systems we show the feasibility of three-dimensional true fast imaging with steady-state precession (FISP) to fill this gap. We applied a three-dimensional true-FISP protocol with voxel sizes down to 0.5 x 0.5 x 0.5 mm and acquisition times of approximately 8 min on a 1.5-T Sonata (Siemens, Erlangen, Germany) magnetic resonance scanner. The sequence was included into routine brain imaging protocols for patients with cerebrospinal-fluid-related intracranial pathology. Images from 20 patients and 20 healthy volunteers were evaluated by two neuroradiologists with respect to diagnostic image quality and artifacts. All true-FISP scans showed excellent imaging quality free of artifacts in patients and volunteers. They were valuable for the assessment of anatomical and pathologic aspects of the included patients. High-resolution true-FISP imaging is a valuable adjunct for the exploration and neuronavigation of intracranial pathologies especially if cerebrospinal fluid is involved. (orig.)

  15. On the necessity of identifying the true parameter in adaptive LQ control

    NARCIS (Netherlands)

    Polderman, Jan W.

    1986-01-01

    In adaptive control problems one may drop the requirement of identifying the true system in order to simplify the problem of control. It will be shown that in the adaptive LQ control problem this does not at all lead to an easier problem.

  16. Case Report: A true median facial cleft (crano-facial dysraphia ...

    African Journals Online (AJOL)

    Case Report: A true median facial cleft (crano-facial dysraphia, atessier type O) in Bingham University Teaching Hospital, Jos. ... Patient had a multidisciplinary care by the obstetrician, Neonatologist, anesthesiologist and the plastic surgery team who scheduled a soft tissue repair of the upper lip defect, columella and ...

  17. True to the Language Game: African American Discourse, Cultural Politics, and Pedagogy

    Science.gov (United States)

    Gilyard, Keith

    2011-01-01

    In "True to the Language Game", Keith Gilyard, one of the major African American figures to emerge in language and cultural studies, makes his most seminal work available in one volume. This collection of new and previously published essays contains Gilyard's most relevant scholarly contributions to deliberations about linguistic diversity,…

  18. MODEL PENSKORAN PARTIAL CREDIT PADA BUTIR MULTIPLE TRUE-FALSE BIDANG FISIKA

    Directory of Open Access Journals (Sweden)

    Wasis Wasis

    2013-01-01

    Full Text Available Tujuan penelitian ini menghasilkan model penskoran politomus untuk respons butir multiple true-false, sehingga dapat mengestimasi secara lebih akurat kemampuan di bidang fisika. Pengembangan penskoran menggunakan Four-D model dan diuji akurasinya melalui penelitian empiris dan simulasi. Penelitian empiris menggunakan 15 butir multiple true-false yang diambil dari soal UMPTN tahun 1996-2006 dan dikenakan pada 410 mahasiswa baru FMIPA Universitas Negeri Surabaya angkatan tahun 2007. Respons peserta tes diskor dengan tiga model partial credit (PCM I; II; dan III dan secara dikotomus. Hasil penskoran dianalisis dengan program Quest untuk mendapat-kan estimasi tingkat kesukaran butir (δ dan estimasi ke-mampuan peserta (θ untuk menentukan nilai fungsi informasi tes dan kesalahan baku estimasi. Penelitian simulasi mengguna-kan data bangkitan berdasarkan parameter empiris (δ dan θ memakai program statistik SAS dan akurasi estimasinya di-analisis dengan metode root mean squared error (RMSE. Hasil penelitian ini menunjukkan: (i Penskoran PCM dengan pem-bobotan mampu mengestimasi kemampuan lebih akurat di-bandingkan tanpa pembobotan maupun secara dikotomus; (ii Semakin banyak jumlah kategori dalam penskoran partial credit, semakin akurat. Kata kunci: model penskoran partial credit, butir multiple true-false ____________________________________________________________ THE PARTIAL CREDIT SCORING MODEL FOR THE MULTIPLE TRUE-FALSE BUTIRS IN PHYSICS Abstract This study is an attempt to overcome the weaknesses. This study aims to produce a polytomous scoring model for responses to multiple true-false butirs in order to get a more accurate estimation of abilities in physics. It adopts the Four-D model and its accuracy is assessed through empirical and simulation studies. The empirical study employed 15 multiple true-false butirs taken from the New Students Entrance Test of State University the year of 1996–2006. It administered to 410 new students enrolled

  19. Brucella Antibodies in Alaskan True Seals and Eared Seals—Two Different Stories

    Directory of Open Access Journals (Sweden)

    Ingebjørg H. Nymo

    2018-01-01

    Full Text Available Brucella pinnipedialis was first isolated from true seals in 1994 and from eared seals in 2008. Although few pathological findings have been associated with infection in true seals, reproductive pathology including abortions, and the isolation of the zoonotic strain type 27 have been documented in eared seals. In this study, a Brucella enzyme-linked immunosorbent assay (ELISA and the Rose Bengal test (RBT were initially compared for 206 serum samples and a discrepancy between the tests was found. Following removal of lipids from the serum samples, ELISA results were unaltered while the agreement between the tests was improved, indicating that serum lipids affected the initial RBT outcome. For the remaining screening, we used ELISA to investigate the presence of Brucella antibodies in sera of 231 eared and 1,412 true seals from Alaskan waters sampled between 1975 and 2011. In eared seals, Brucella antibodies were found in two Steller sea lions (Eumetopias jubatus (2% and none of the 107 Northern fur seals (Callorhinus ursinus. The low seroprevalence in eared seals indicate a low level of exposure or lack of susceptibility to infection. Alternatively, mortality due to the Brucella infection may remove seropositive animals from the population. Brucella antibodies were detected in all true seal species investigated; harbor seals (Phoca vitulina (25%, spotted seals (Phoca largha (19%, ribbon seals (Histriophoca fasciata (16%, and ringed seals (Pusa hispida hispida (14%. There was a low seroprevalence among pups, a higher seroprevalence among juveniles, and a subsequent decreasing probability of seropositivity with age in harbor seals. Similar patterns were present for the other true seal species; however, solid conclusions could not be made due to sample size. This pattern is in accordance with previous reports on B. pinnipedialis infections in true seals and may suggest environmental exposure to B. pinnipedialis at the juvenile stage, with a

  20. SU-F-E-19: A Novel Method for TrueBeam Jaw Calibration

    Energy Technology Data Exchange (ETDEWEB)

    Corns, R; Zhao, Y; Huang, V [Fraser Valley Cancer Centre - BC Cancer Agency, Surrey, BC (United Kingdom)

    2016-06-15

    Purpose: A simple jaw calibration method is proposed for Varian TrueBeam using an EPID-Encoder combination that gives accurate fields sizes and a homogeneous junction dose. This benefits clinical applications such as mono-isocentric half-beam block breast cancer or head and neck cancer treatment with junction/field matching. Methods: We use EPID imager with pixel size 0.392 mm × 0.392 mm to determine the radiation jaw position as measured from radio-opaque markers aligned with the crosshair. We acquire two images with different symmetric field sizes and record each individual jaw encoder values. A linear relationship between each jaw’s position and its encoder value is established, from which we predict the encoder values that produce the jaw positions required by TrueBeam’s calibration procedure. During TrueBeam’s jaw calibration procedure, we move the jaw with the pendant to set the jaw into position using the predicted encoder value. The overall accuracy is under 0.1 mm. Results: Our in-house software analyses images and provides sub-pixel accuracy to determine field centre and radiation edges (50% dose of the profile). We verified the TrueBeam encoder provides a reliable linear relationship for each individual jaw position (R{sup 2}>0.9999) from which the encoder values necessary to set jaw calibration points (1 cm and 19 cm) are predicted. Junction matching dose inhomogeneities were improved from >±20% to <±6% using this new calibration protocol. However, one technical challenge exists for junction matching, if the collimator walkout is large. Conclusion: Our new TrueBeam jaw calibration method can systematically calibrate the jaws to crosshair within sub-pixel accuracy and provides both good junction doses and field sizes. This method does not compensate for a larger collimator walkout, but can be used as the underlying foundation for addressing the walkout issue.

  1. Significance assessment of the external control effects of lecturers

    Directory of Open Access Journals (Sweden)

    Kurbatova Margarita, V.

    2015-06-01

    Full Text Available The state policy regarding higher education has changed in the last decade. These changes were part of the efficiency programs of the public sector. Governments of different countries ruined previously existing system of higher education state regulation and attempted to build the quasi-market structure in the higher education industry. Such transformations served as timely and progressive reforms in the recent studies of the economics of education. Substitution of bureaucratic management mechanisms and modern competition managerial tools are articulated. Economic and institutional and sociological studies on the effects of the introduction of quasi-markets and managerial tools in higher education governance oppose to orthodox market approach. They drew attention to the fact that evaluation methods and improve the effectiveness of organizations and employees that are typical of the private sector often produce results that differ from those in the public sector. To assess the consequences of the introduction of managerial tools of external control activities of university lecturers used a methodology based on the allocation of the individual structural components (effects and building on their basis of a multi-level hierarchical model in the research. Each component of the model (single effect is characterized by a degree of significance (importance and the degree of severity. The results of the systematization and assessment of the significance of the effects of external control activity of lecturers of Russian universities implemented in conditions of quasi-market mechanisms of the higher education system are highlighted in the paper.

  2. Singled out?

    Science.gov (United States)

    Waller, Frank

    2004-03-01

    The increasing use of single use medical devices is being driven by a growing awareness of iatrogenic (from the Greek; caused by the doctor) and nosocomial infections. Public health perceptions relating to transmissible spongiform encephalopathies, specifically variant Creutzfeldt-Jakob disease (vCJD), the Human Immunodeficiency Virus (HIV) and Hepatitis B are high on the political agenda and a matter of concern to healthcare professionals.

  3. Disinhibition of negative true self for identity reconstructions in cyberspace: Advancing self-discrepancy theory for virtual setting.

    Directory of Open Access Journals (Sweden)

    Chuan Hu

    Full Text Available In face-to-face communications, to avoid sanctions and disapproval from others, people are more likely to hide negative aspects of their true self (such as socially undesirable personalities, minds, beliefs and consciousness to avoid conflict with social norms and laws. The anonymity of cyberspace provides people a unique environment to behave more freely and openly with less restraint from the real word. Existing research related to online true self expression has mainly explored true self as an independent aspect of self. Regarding true self as a two-dimensional concept, this study investigates true self from the perspective of individuals' self-guide and identity reconstruction in both online and offline world. Using qualitative research methods, the current study investigates 57 participants through interviews and questionnaires. Content analysis reveals four factors that motivate people to express more true self (especially negative true self when reconstructing their online identity and involve true self as a part of their self-guide in anonymous environment. By incorporating true self as an important part of individuals' self-guide and identity online, the current study advances self-discrepancy theory, making it more comprehensive for cyberspace. The results are also interpreted based on self-determination theory. The theoretical contributions of this study are discussed and practical implications are also presented.

  4. Modeling the influence of investigator bias on the elicitation of true and false confessions.

    Science.gov (United States)

    Narchet, Fadia M; Meissner, Christian A; Russano, Melissa B

    2011-12-01

    The aim of this study was to model various social and cognitive processes believed to be associated with true and false confessions by exploring the link between investigative biases and what occurs in the interrogation room. Using the Russano et al. (Psychol Sci 16:481-486, 2005) paradigm, this study explored how perceptions of guilt influenced the frequency and type of interrogation tactics used, suspect's perceptions of the interrogation process, the likelihood of confession, and investigator's resulting perceptions of culpability. Results suggested that investigator bias led to the increased use of minimization tactics and thereby increased the likelihood of false confessions by innocent participants. In contrast, the manipulation of investigator bias had no direct or indirect influence on guilty participants. These findings confirm the important role of investigator bias and improve our understanding of the decision-making process associated with true and false confessions.

  5. A true random number generator based on mouse movement and chaotic cryptography

    International Nuclear Information System (INIS)

    Hu Yue; Liao Xiaofeng; Wong, Kwok-wo; Zhou Qing

    2009-01-01

    True random number generators are in general more secure than pseudo random number generators. In this paper, we propose a novel true random number generator which generates a 256-bit random number by computer mouse movement. It is cheap, convenient and universal for personal computers. To eliminate the effect of similar movement patterns generated by the same user, three chaos-based approaches, namely, discretized 2D chaotic map permutation, spatiotemporal chaos and 'MASK' algorithm, are adopted to post-process the captured mouse movements. Random bits generated by three users are tested using NIST statistical tests. Both the spatiotemporal chaos approach and the 'MASK' algorithm pass the tests successfully. However, the latter has a better performance in terms of efficiency and effectiveness and so is more practical for common personal computer applications.

  6. An X-ray CCD signal generator with true random arrival time

    International Nuclear Information System (INIS)

    Huo Jia; Xu Yuming; Chen Yong; Cui Weiwei; Li Wei; Zhang Ziliang; Han Dawei; Wang Yusan; Wang Juan

    2011-01-01

    An FPGA-based true random signal generator with adjustable amplitude and exponential distribution of time interval is presented. Since traditional true random number generators (TRNG) are resource costly and difficult to transplant, we employed a method of random number generation based on jitter and phase noise in ring oscillators formed by gates in an FPGA. In order to improve the random characteristics, a combination of two different pseudo-random processing circuits is used for post processing. The effects of the design parameters, such as sample frequency are discussed. Statistical tests indicate that the generator can well simulate the timing behavior of random signals with Poisson distribution. The X-ray CCD signal generator will be used in debugging the CCD readout system of the Low Energy X-ray Instrument onboard the Hard X-ray Modulation Telescope (HXMT). (authors)

  7. Current technology and advances in true re-use of effluents

    International Nuclear Information System (INIS)

    Cillie, G.G.

    1975-01-01

    Increasing exploitation of natural water resources has necessitated true re-use of effluents. Such planned re-use is preferable to the indirect or incidental re-use which has hitherto been practised, sometimes indiscriminately. Modern technology provides the means for renovating effluents to any desired quality standard, including human consumption. The major obstacles still confronting widespread application of true re-use are the removal of nitrogen compounds and trace organic residues, including insecticides, herbicides and carcinogens. The need to guarantee hygienic quality by removal or destruction of all pathogens, including viruses and parasites, constitutes a major cost item. Radiation techniques may well be applied for sterilization and for destruction of organic radicals. A combination of various unit processes, for which design criteria and hardware are readily available, can be used to produce potable water at a cost of some 10 cents/m 3 for a 45 Ml/d plant. (author)

  8. A Case Study of True and Fair View Override in Financial Reporting

    Directory of Open Access Journals (Sweden)

    Ho Horace

    2016-12-01

    Full Text Available This paper documents a case study of true and fair view override in financial reporting by a multinational firm subject to International Financial Reporting Standards (IFRSs. The 2009 Interim Report of HSBC Holdings plc states that HSBC departed from the requirements of IAS 32 Financial Instruments: Presentation (IAS 32. Notwithstanding its noncompliance with the IFRSs, HSBC (2009 concluded that “the interim consolidated financial statements prepared on this basis presented fairly, and gave a true and fair view of the Group’s financial position, financial performance and cash flows” (p. 2. The purpose of this paper is to evaluate critically the accounting treatment in light of the relevant requirements of the IFRSs and the implications for professional accounting standards arising from this departure.

  9. Prion protein immunocytochemistry helps to establish the true incidence of prion diseases.

    Science.gov (United States)

    Lantos, P L; McGill, I S; Janota, I; Doey, L J; Collinge, J; Bruce, M T; Whatley, S A; Anderton, B H; Clinton, J; Roberts, G W

    1992-11-23

    Creutzfeldt-Jakob disease (CJD) and Gerstmann-Strüssler-Scheinker disease (GSSD) are transmissible spongiform encephalopathies or prion diseases affecting man. It has been reported that prion diseases may occur without the histological hallmarks of spongiform encephalopathies: vacuolation of the cerebral grey matter, neuronal loss and astrocytosis. These cases without characteristic neuropathology may go undiagnosed and consequently the true incidence of transmissible dementias is likely to have been under-estimated. Immunocytochemistry using antibodies to prion protein gives positive staining of these cases, albeit the pattern of immunostaining differs from that seen in typical forms. Accumulation of prion protein is a molecular hallmark of prion diseases, and thus a reproducible, speedy and cost-efficient immunocytochemical screening of unusual dementias may help to establish the true incidence of prion diseases.

  10. Dysphagia, hoarseness, and unilateral true vocal fold motion impairment following anterior cervical diskectomy and fusion.

    Science.gov (United States)

    Baron, Eli M; Soliman, Ahmed M S; Gaughan, John P; Simpson, Lisa; Young, William F

    2003-11-01

    The charts of 100 patients who underwent anterior cervical diskectomy with fusion performed at our institution between January 1996 and February 1999 were reviewed. The incidences of hoarseness, dysphagia, and unilateral true vocal fold motion impairment were calculated. Univariate logistic regression was used to estimate the relationship of several patient and technical factors to the rates of occurrence of hoarseness and dysphagia. Patient age was found to be a significant predictor of postoperative dysphagia (p dysphagia, hoarseness, and unilateral true vocal fold motion impairment in the literature were calculated as 12.3%, 4.9%, and 1.4%, respectively. We conclude that dysphagia, hoarseness, and unilateral vocal fold motion impairment continue to remain significant complications of anterior cervical diskectomy with fusion. Older patients may be at higher risk for dysphagia.

  11. Broadband demonstrations of true-time delay using linear sideband chirped programming and optical coherent transients

    International Nuclear Information System (INIS)

    Reibel, R.R.; Barber, Z.W.; Fischer, J.A.; Tian, M.; Babbitt, W.R.

    2004-01-01

    Linear sideband chirped (LSC) programming is introduced as a means of configuring spatial-spectral holographic gratings for optical coherent transient processors. Similar to linear frequency chirped programming, LSC programming allows the use of broadband integrated electro-optic phase modulators to produce chirps instead of using elaborate broadband chirped lasers. This approach has several advantages including the ability to use a stabilized laser for the optical carrier as well as stable, reproducible chirped optical signals when the modulator is driven digitally. Using LSC programming, we experimentally demonstrate broadband true-time delay as a proof of principle for the optical control of phased array radars. Here both cw phase modulated and binary phase shift keyed probe signals are true-time delayed with bandwidths of 1 GHz and delay resolutions better than 60 ps

  12. The young Marx on constituent power and “true democracy.”

    DEFF Research Database (Denmark)

    Flohr, Mikkel

    Marx and Marxism is commonly charged with having neglected politics and the development of a theory of politics. However, this presumption ignores Marx’s unfinished and unpublished 1843 Critique of Hegel’s Doctrine of State, where he engaged political theory at length – an engagement, which...... propelled him towards his subsequent critique of political economy. It is the aim of the proposed paper to reconstruct and reinterpret his argument focusing in particular on his conceptualization of constituent power and “true democracy.” In the 1843 Critique Marx argues that democracy is the foundation...... the conflicts of civil society. Marx therefore concludes that all these political forms are democracies in contradiction with themselves. Marx proceeds to suggest that it is possible to overcome these contradictions and develop an adequate political form of democracy, which he describes as “true democracy...

  13. Acquired Bilateral Longitudinal True Leukonychia in a 35-year-old Woman

    Science.gov (United States)

    Mokhtari, Fatemeh; Mozafarpoor, Samaneh; Nouraei, Saeid; Nilforoushzadeh, Mohammad Ali

    2016-01-01

    Acquired bilateral longitudinal true leukonychia is a rare disorder. We present a case of a 35-year-old healthy woman presented with this unusual and rare manifestation. She mentioned a history of unprotected exposure to detergents and bleaching chemical agents. Considering her low zinc level, she was prescribed with zinc capsules and recommended to avoid chemical substances for 6 months. During bimonthly follow-up, her zinc level turned normal, and leukonychia subsequently disappeared. Bilateral longitudinal true leukonychia in the nails due to zinc deficiency and exposure to chemical substances has not been reported previously. Direct and indirect effects of chemical substances on matrix and the effect of zinc deficiency on healing process should be considered in these cases. PMID:27857831

  14. System for evaluation of the true average input-pulse rate

    International Nuclear Information System (INIS)

    Eichenlaub, D.P.; Garrett, P.

    1977-01-01

    The description is given of a digital radiation monitoring system making use of current digital circuit and microprocessor for rapidly processing the pulse data coming from remote radiation controllers. This system analyses the pulse rates in order to determine if a new datum is statistically the same as that previously received. Hence it determines the best possible average time for itself. So long as the true average pulse rate stays constant, the time required to establish an average can increase until the statistical error is under the desired level, i.e. 1%. When the digital processing of the pulse data indicates a change in the true average pulse rate, the time required to establish an average can be reduced so as to improve the response time of the system at the statistical error. This concept includes a fixed compromise between the statistical error and the response time [fr

  15. Emissions Trading Schemes under IFRS - Towards a “true and fair view”

    OpenAIRE

    Haupt, Madlen; Ismer, Roland

    2011-01-01

    This research paper seeks to contribute to the latest discussions on the financial reporting for emissions trading schemes. It starts out by giving an overview of the International Financial Reporting Standards (IFRS) accounting policies, which are currently applied by the majority of participants in the EU Emissions Trading Scheme. It then argues that in order to fulfil the aims of financial reporting under IFRS, namely to provide a true and fair view, accounting must depict CO2 as a cost of...

  16. Knowledge Management: “What If That’s Not True?”

    International Nuclear Information System (INIS)

    Barnes, S.

    2016-01-01

    Full text: Knowledge management, critical thinking, creativity, and innovation would seem to be different ideas and disciplines, but in fact they can and do enable and enrich each other as in the process of addressing the question: what if that’s not true. This technical brief explores the connections between critical thinking, creativity, innovation, and knowledge management. The result of this interconnectedness is observed in efficiency and effectiveness, competitive advantage as well as in risk informed decision making. (author

  17. Unfolding of true distributions from experimental data distorted by detectors with finite resolutions

    International Nuclear Information System (INIS)

    Gagunashvili, N.D.

    1993-01-01

    A new procedure for unfolding the true distribution from experimental data distorted by a detector is proposed. For the given detector a result can be found by the least squares method, hence, without bias and involving minimal statistical errors. Stability of the result is achieved at the expense of its information content and/or using additional information on the shape of the distributions to be measured. The method may be applied for detectors with linear or nonlinear distortions. 8 refs.; 5 figs

  18. New true-triaxial rock strength criteria considering intrinsic material characteristics

    Science.gov (United States)

    Zhang, Qiang; Li, Cheng; Quan, Xiaowei; Wang, Yanning; Yu, Liyuan; Jiang, Binsong

    2018-02-01

    A reasonable strength criterion should reflect the hydrostatic pressure effect, minimum principal stress effect, and intermediate principal stress effect. The former two effects can be described by the meridian curves, and the last one mainly depends on the Lode angle dependence function. Among three conventional strength criteria, i.e. Mohr-Coulomb (MC), Hoek-Brown (HB), and Exponent (EP) criteria, the difference between generalized compression and extension strength of EP criterion experience a firstly increase then decrease process, and tends to be zero when hydrostatic pressure is big enough. This is in accordance with intrinsic rock strength characterization. Moreover, the critical hydrostatic pressure I_c corresponding to the maximum difference of between generalized compression and extension strength can be easily adjusted by minimum principal stress influence parameter K. So, the exponent function is a more reasonable meridian curves, which well reflects the hydrostatic pressure effect and is employed to describe the generalized compression and extension strength. Meanwhile, three Lode angle dependence functions of L_{{MN}}, L_{{WW}}, and L_{{YMH}}, which unconditionally satisfy the convexity and differential requirements, are employed to represent the intermediate principal stress effect. Realizing the actual strength surface should be located between the generalized compression and extension surface, new true-triaxial criteria are proposed by combining the two states of EP criterion by Lode angle dependence function with a same lode angle. The proposed new true-triaxial criteria have the same strength parameters as EP criterion. Finally, 14 groups of triaxial test data are employed to validate the proposed criteria. The results show that the three new true-triaxial exponent criteria, especially the Exponent Willam-Warnke criterion (EPWW) criterion, give much lower misfits, which illustrates that the EP criterion and L_{{WW}} have more reasonable meridian

  19. Validation of Tendril TrueHome Using Software-to-Software Comparison

    Energy Technology Data Exchange (ETDEWEB)

    Maguire, Jeffrey B [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Horowitz, Scott G [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Moore, Nathan [Tendril, Boulder, CO (United States); Sullivan, Patrick [Tendril, Boulder, CO (United States)

    2017-09-01

    This study performed comparative evaluation of EnergyPlus version 8.6 and Tendril TrueHome, two physics-based home energy simulation models, to identify differences in energy consumption predictions between the two programs and resolve discrepancies between them. EnergyPlus is considered a benchmark, best-in-class software tool for building energy simulation. This exercise sought to improve both software tools through additional evaluation/scrutiny.

  20. Effects of Some Additives on In Vitro True Digestibility of Wheat and Soybean Straw Pellets

    OpenAIRE

    Kılıc Unal; Gulecyuz Emre

    2017-01-01

    This study was aimed to explore the nutrient content, relative feed values (RFV) and in vitro true digestibilities (IVTD) of wheat straw and soybean straw pellets produced with the addition of molasses, guar meal and sepiolite. In this experiment, 16 groups were created for 2 different straws (wheat/soybean straws), 2 different sepiolite applications (available/not available) and 4 different applications (control, guar meal, molasses, guar meal+molasses) in accordance with the 2×2×4 factorial...

  1. Digestibility coefficient and true digestible amino acid values of different cultivars of maize for poultry

    Directory of Open Access Journals (Sweden)

    Márcia Antonia Bartolomeu Agustini

    2015-04-01

    Full Text Available The digestibility and true digestible amino acid content of eight cultivars of maize was determined using the method of force-feeding roosters cecectomized. The experimental design was completely randomized, represented by eight cultivars, five replicates and a rooster each. Five roosters were kept fasting for corrections corresponding to metabolic and endogenous losses of amino acids. Significant differences (P <0.05 among maize cultivars for the true digestibility of amino acids, methionine, threonine, arginine, cystine and serine were observed. The values of true digestibility coefficients for essential amino acids, for methionine, threonine and arginine ranged from 85.61 to 93.57%, from 66.27 to 84.97% and 83.39 to 93.10% respectively. For the other essential amino acids, the average values were: 72.84% for lysine, 85.64% for methionine+cystine, 87.29% for histidine, 85.33% for valine, 87.11% for isoleucine, 94.04% for leucine and 90.65% for phenylalanine. The true digestibility coefficients of nonessential amino acids cystine and serine that showed significant difference ranged from 73.97 to 89.21% and from 77.31 to 92.68%, respectively. For other non-essential amino acids, average values were 88.28% for alanine, 82.68% for aspartic acid, 92.19% for glutamic acid and 87.84% for tyrosine. Due to the variations observed, it is recommended periodic analyzes of maize cultivars used to formulate diets, to ensure the feed quality and the performance of the animals.

  2. True Multilateral Indexes for International Comparisons of Purchasing Power and Real Income

    OpenAIRE

    J.P. Neary

    1997-01-01

    I consider the problem of choosing index numbers of purchasing power and real income for international comparisons. I show that the desirable properties of methods based on the Fisher "Ideal" index do not extend to multilateral comparisons, except when tastes are homothetic. By contrast, the Geary method, which underlies the Penn World Tables, provides an approximation to a set of "true" exchange rate indexes which have many desirable properties. In particular, if demands exhibit generalized ...

  3. Slow light in a semiconductor waveguide for true-time delay applications in microwave photonics

    DEFF Research Database (Denmark)

    Öhman, Filip; Yvind, Kresten; Mørk, Jesper

    2007-01-01

    We have investigated the slowand fast light properties of a semiconductor waveguide device employing concatenated gain and absorber sections. This letter presents the experimental results as well as theoretical modeling. A large phase shift of 110 and a true-time delay of more than 150 ps are dem...... are demonstrated. The combination of amplitude and phase control of the modulated signal shows great promise for applications within microwave photonics....

  4. Analysis of on-line learning when a moving teacher goes around a true teacher

    OpenAIRE

    Miyoshi, Seiji; Okada, Masato

    2005-01-01

    In the framework of on-line learning, a learning machine might move around a teacher due to the differences in structures or output functions between the teacher and the learning machine or due to noises. The generalization performance of a new student supervised by a moving machine has been analyzed. A model composed of a true teacher, a moving teacher and a student that are all linear perceptrons with noises has been treated analytically using statistical mechanics. It has been proven that ...

  5. Separating true V0's from combinatoric background with a neural network

    International Nuclear Information System (INIS)

    Justice, M.

    1997-01-01

    A feedforward multilayered neural network has been trained to ''recognize'' true V0's in the presence of a large combinatoric background using simulated data for 2 GeV/nucleon Ni + Cu interactions. The resulting neural network filter has been applied to actual data from the EOS TPC experiment. An enhancement of signal to background over more traditional selection mechanisms has been observed. (orig.)

  6. Pseudorandom number generation using chaotic true orbits of the Bernoulli map

    Energy Technology Data Exchange (ETDEWEB)

    Saito, Asaki, E-mail: saito@fun.ac.jp [Future University Hakodate, 116-2 Kamedanakano-cho, Hakodate, Hokkaido 041-8655 (Japan); Yamaguchi, Akihiro [Fukuoka Institute of Technology, 3-30-1 Wajiro-higashi, Higashi-ku, Fukuoka 811-0295 (Japan)

    2016-06-15

    We devise a pseudorandom number generator that exactly computes chaotic true orbits of the Bernoulli map on quadratic algebraic integers. Moreover, we describe a way to select the initial points (seeds) for generating multiple pseudorandom binary sequences. This selection method distributes the initial points almost uniformly (equidistantly) in the unit interval, and latter parts of the generated sequences are guaranteed not to coincide. We also demonstrate through statistical testing that the generated sequences possess good randomness properties.

  7. A true branchial fistula in the context of branchiootic syndrome: challenges of diagnosis and management.

    Science.gov (United States)

    Jovic, Thomas H; Saldanha, Francesca; Kuo, Rachel; Ahmad, Tariq

    2014-09-01

    The presence of a branchial fistula with communication both internally and externally: a 'true' branchial fistula is rare, and may arise in the context of autosomal dominant conditions such as branchiootic syndrome and branchiootorenal syndrome. We discuss the case of a true branchial fistula, which recurred after initial surgical excision, in a patient with branchiootic syndrome. The residual tract was dissected in a second operation through stepladder neck incisions and removed in toto via an intraoral approach. No renal abnormalities were detected on investigation with ultrasound. Incomplete excision of a branchial sinus is likely to cause recurrence however intraoperative visualisation of the tract can can sometimes prove challenging. An combined intraoral and external approach aids delineation and tract definition when there is a true branchial fistula and can therefore facilitate a complete excision. Suspicion of an hereditary aetiology should be raised in patients with bilateral or preauricular features, or a positive family history, which may then prompt additional renal and genetic investigation. Copyright © 2014 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

  8. How Fuzzy-Trace Theory Predicts True and False Memories for Words, Sentences, and Narratives

    Science.gov (United States)

    Reyna, Valerie F.; Corbin, Jonathan C.; Weldon, Rebecca B.; Brainerd, Charles J.

    2016-01-01

    Fuzzy-trace theory posits independent verbatim and gist memory processes, a distinction that has implications for such applied topics as eyewitness testimony. This distinction between precise, literal verbatim memory and meaning-based, intuitive gist accounts for memory paradoxes including dissociations between true and false memory, false memories outlasting true memories, and developmental increases in false memory. We provide an overview of fuzzy-trace theory, and, using mathematical modeling, also present results demonstrating verbatim and gist memory in true and false recognition of narrative sentences and inferences. Results supported fuzzy-trace theory's dual-process view of memory: verbatim memory was relied on to reject meaning-consistent, but unpresented, sentences (via recollection rejection). However, verbatim memory was often not retrieved, and gist memory supported acceptance of these sentences (via similarity judgment and phantom recollection). Thus, mathematical models of words can be extended to explain memory for complex stimuli, such as narratives, the kind of memory interrogated in law. PMID:27042402

  9. New approach to calculate the true-coincidence effect of HpGe detector

    Energy Technology Data Exchange (ETDEWEB)

    Alnour, I. A., E-mail: aaibrahim3@live.utm.my, E-mail: ibrahim.elnour@yahoo.com [Department of Physics, Faculty of Pure and Applied Science, International University of Africa, 12223 Khartoum (Sudan); Wagiran, H. [Department of Physics, Faculty of Science, Universiti Teknologi Malaysia, 81310 UTM Skudai,Johor (Malaysia); Ibrahim, N. [Faculty of Defence Science and Technology, National Defence University of Malaysia, Kem Sungai Besi, 57000 Kuala Lumpur (Malaysia); Hamzah, S.; Elias, M. S. [Malaysia Nuclear Agency (MNA), Bangi, 43000 Kajang, Selangor D.E. (Malaysia); Siong, W. B. [Chemistry Department, Faculty of Resource Science & Technology, Universiti Malaysia Sarawak, 94300 Kota Samarahan, Sarawak (Malaysia)

    2016-01-22

    The corrections for true-coincidence effects in HpGe detector are important, especially at low source-to-detector distances. This work established an approach to calculate the true-coincidence effects experimentally for HpGe detectors of type Canberra GC3018 and Ortec GEM25-76-XLB-C, which are in operation at neutron activation analysis lab in Malaysian Nuclear Agency (NM). The correction for true-coincidence effects was performed close to detector at distances 2 and 5 cm using {sup 57}Co, {sup 60}Co, {sup 133}Ba and {sup 137}Cs as standard point sources. The correction factors were ranged between 0.93-1.10 at 2 cm and 0.97-1.00 at 5 cm for Canberra HpGe detector; whereas for Ortec HpGe detector ranged between 0.92-1.13 and 0.95-100 at 2 and 5 cm respectively. The change in efficiency calibration curve of the detector at 2 and 5 cm after correction was found to be less than 1%. Moreover, the polynomial parameters functions were simulated through a computer program, MATLAB in order to find an accurate fit to the experimental data points.

  10. Measurement of true ileal phosphorus digestibility in meat and bone meal for broiler chickens.

    Science.gov (United States)

    Mutucumarana, R K; Ravindran, V; Ravindran, G; Cowieson, A J

    2015-07-01

    An experiment was conducted to estimate true ileal phosphorus (P:) digestibility of 3 meat and bone meal samples (MBM-1, MBM-2: , and MBM-3:) for broiler chickens. Four semipurified diets were formulated from each sample to contain graded concentrations of P. The experiment was conducted as a completely randomized design with 6 replicates (6 birds per replicate) per dietary treatment. A total of 432 Ross 308 broilers were assigned at 21 d of age to the 12 test diets. The apparent ileal digestibility coefficient of P was determined by the indicator method, and the linear regression method was used to determine the true P digestibility coefficient. The apparent ileal digestibility coefficient of P in birds fed diets containing MBM-1 and MBM-2 was unaffected by increasing dietary concentrations of P (P > 0.05). The apparent ileal digestibility coefficient of P in birds fed the MBM-3 diets decreased with increasing P concentrations (linear, P digestibility of MBM-1, MBM-2, and MBM-3 was determined to be 0.693, 0.608, and 0.420, respectively. True ileal P digestibility coefficients determined for MBM-1 and MBM-2 were similar (P digestible P contents of MBM-1, MBM-2, and MBM-3 were determined to be 37.5 and 26.0; 60.2 and 36.6; and 59.8 and 25.1 g/kg, respectively, on an as-fed basis. © 2015 Poultry Science Association Inc.

  11. Scaling rates of true polar wander in convecting planets and moons

    Science.gov (United States)

    Rose, Ian; Buffett, Bruce

    2017-12-01

    Mass redistribution in the convecting mantle of a planet causes perturbations in its moment of inertia tensor. Conservation of angular momentum dictates that these perturbations change the direction of the rotation vector of the planet, a process known as true polar wander (TPW). Although the existence of TPW on Earth is firmly established, its rate and magnitude over geologic time scales remain controversial. Here we present scaling analyses and numerical simulations of TPW due to mantle convection over a range of parameter space relevant to planetary interiors. For simple rotating convection, we identify a set of dimensionless parameters that fully characterize true polar wander. We use these parameters to define timescales for the growth of moment of inertia perturbations due to convection and for their relaxation due to true polar wander. These timescales, as well as the relative sizes of convective anomalies, control the rate and magnitude of TPW. This analysis also clarifies the nature of so called "inertial interchange" TPW events, and relates them to a broader class of events that enable large and often rapid TPW. We expect these events to have been more frequent in Earth's past.

  12. Noninvasive Recording of True-to-Form Fetal ECG during the Third Trimester of Pregnancy

    Directory of Open Access Journals (Sweden)

    Istvan Peterfi

    2014-01-01

    Full Text Available Objective. The aim of the study was to develop a complex electrophysiological measurement system (hardware and software which uses the methods of electrophysiology and provides significant information about the intrauterine status of the fetus, intending to obtain true-to-form, morphologically evaluated fetal ECG from transabdominal maternal lead. Results. The present method contains many novel ideas that allow creating true-to-form noninvasive fetal ECG in the third trimester of the pregnancy in 80% of the cases. Such ideas are the telemetric data collection, the “cleanse” of the real time recording from the maternal ECG, and the use of the cardiotocograph (CTG that allows identifying the fetal heart events. The advantage of this developed system is that it does not require any qualified staff, because both the extraction of the information from the abdominal recording and the processing of the data are automatic. Discussion. Although the idea of a noninvasive fetal electrocardiography is more than 100 years old still there is no simple, effective, and cheap method available that would enable an extensive use. This developed system can be used in the third trimester of the pregnancy efficiently. It can produce true-to-form fetal ECGs with amplitude less than 10 µV.

  13. Methods for obtaining true particle size distributions from cross section measurements

    Energy Technology Data Exchange (ETDEWEB)

    Lord, Kristina Alyse [Iowa State Univ., Ames, IA (United States)

    2013-01-01

    Sectioning methods are frequently used to measure grain sizes in materials. These methods do not provide accurate grain sizes for two reasons. First, the sizes of features observed on random sections are always smaller than the true sizes of solid spherical shaped objects, as noted by Wicksell [1]. This is the case because the section very rarely passes through the center of solid spherical shaped objects randomly dispersed throughout a material. The sizes of features observed on random sections are inversely related to the distance of the center of the solid object from the section [1]. Second, on a plane section through the solid material, larger sized features are more frequently observed than smaller ones due to the larger probability for a section to come into contact with the larger sized portion of the spheres than the smaller sized portion. As a result, it is necessary to find a method that takes into account these reasons for inaccurate particle size measurements, while providing a correction factor for accurately determining true particle size measurements. I present a method for deducing true grain size distributions from those determined from specimen cross sections, either by measurement of equivalent grain diameters or linear intercepts.

  14. The true absorption of 131I, and its transfer to milk in cows given different stable iodine diets

    International Nuclear Information System (INIS)

    Vandecasteele, C.M.; Van Hees, M.; Hardeman, F.; Voigt, G.; Howard, B.J.

    2000-01-01

    The influence of the stable iodine content in the diet on the absorption of radioiodine and its transfer to cow's milk was investigated for cows at different stages of lactation. Three different rates of stable iodine: a low intake rate of 4 mg d -1 , a moderate intake of 35 mg d -1 and a high rate of 75 mg d -1 were fed to two groups of three lactating cows in mid- and late-lactation. The transfer to milk of a single oral administration of radioiodine was measured for the three different intake rates. The lactation phase had no significant effect on iodine transfer to milk; therefore, the data from the two lactation groups were pooled for further statistical analyses. The mean transfer coefficient values for oral radioiodine to milk increased from 0.020 d l -1 for the low treatment to 0.024 d l -1 for the moderate stable iodine rate. There was a statistically significant decrease in the transfer to milk for the high stable dietary iodine intake rate (mean transfer coefficient=0.018 d l -1 ) compared with the moderate treatment. These differences were not due to effects on absorption since true absorption was complete for all three stable iodine treatments, but rather to differential affinities and saturation levels of the thyroid and milk pathways competing for the available iodine. The same behaviour and comparable values of transfer coefficients (range 0.015-0.020 d l -1 ) were observed for stable iodine

  15. True coincidence-summing corrections for the coincident γ-rays measured with coplanar grid CdZnTe detectors

    International Nuclear Information System (INIS)

    Yuecel, H.; Solmaz, A.N.; Koese, E.; Bor, D.

    2010-01-01

    In this study, true coincidence-summing (TCS) correction factors have been measured for the sources 22 Na, 60 Co, 133 Ba and 152 Eu by use of three large volume coplanar grid CdZnTe (acronym: CZT) detectors. In case of a close-in detection geometry, two different TCS calculation algorithms were used to compute the required TCS correction factors. Both of the algorithms are based on the measured total-to-peak (TTP) ratio and full-energy peak (FEP) efficiency values that were obtained using almost 'single' energy and coincidence-free nuclides. The results for TCS correction factors obtained by two different algorithms were agreeable to each other. The obtained TCS factors were ranged from about 7% to 30.5% in a 2250 mm 3 CZT detector when a close counting geometry was used. For other two detectors with a volume of 1000 and 1687.5 mm 3 , the resulted TCS correction factors were relatively smaller and varied between about 0.1% and 20% at the close counting geometry condition. Therefore, the results indicate that there is a need for the estimation of TCS corrections in CZT detectors, especially when their crystal volumes are greater than 1 cm 3 and these detectors are used in the case of a close-in detection geometry.

  16. Easy and Informative: Using Confidence-Weighted True-False Items for Knowledge Tests in Psychology Courses

    Science.gov (United States)

    Dutke, Stephan; Barenberg, Jonathan

    2015-01-01

    We introduce a specific type of item for knowledge tests, confidence-weighted true-false (CTF) items, and review experiences of its application in psychology courses. A CTF item is a statement about the learning content to which students respond whether the statement is true or false, and they rate their confidence level. Previous studies using…

  17. Final report of the TRUE Block Scale project. 1. Characterisation and model development

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Peter; Byegaard, Johan [Geosigma AB, Uppsala (Sweden); Dershowitz, Bill; Doe, Thomas [Golder Associates Inc., Redmond, WA (United States); Hermanson, Jan [Golder Associates AB (Sweden); Meier, Peter [ANDRA, Chatenay-Malabry (France); Tullborg, Eva-Lena [Terralogica AB (Sweden); Winberg, Anders (ed.) [Conterra AB, Partille (Sweden)

    2002-04-01

    The general objectives of the TRUE Block Scale Project were to 1) increase understanding of tracer transport in a fracture network and to improve predictive capabilities, 2) assess the importance of tracer retention mechanisms (diffusion and sorption) in a fracture network, and 3) assess the link between flow and transport data as a means for predicting transport phenomena. During the period mid 1996 through mid 1999 a 200x250x100 m rock volume was characterised with the purpose of furnishing the basis for successful tracer experiments in a network of conductive structures in the block scale (10-100 m). In total five cored boreholes were drilled as part of the project in an iterative mode with a period of analysis following completion of characterisation, and with a strong component of inter activity with numerical modelling and experimental design, particularly towards the end of the characterisation. The combined use of pressure responses due to drilling and drilling records provided important early information/confirmation of the existence and location of a given structure. Verification of conductors identified from pressure responses was achieved through the use of various flow logging techniques. The usage of the Posiva difference flow log towards the end of the characterisation work enabled identification of discrete conductive fractures with a high resolution. Pressure responses collected during drilling were used to obtain a first assessment of connectivity between boreholes. The transient behaviour of the responses collected during cross-hole interference tests in packed-off boreholes were used to identify families of responses, which correlated well with the identified principal families of structures/fracture networks. The conductive geometry of the investigated rock block is made up of steeply dipping deterministic NW structures and NNW structures. High inflows in the boreholes were for the most part associated with geologically/geometrically identified

  18. Final report of the TRUE Block Scale project. 1. Characterisation and model development

    International Nuclear Information System (INIS)

    Andersson, Peter; Byegaard, Johan; Dershowitz, Bill; Doe, Thomas; Hermanson, Jan; Meier, Peter; Tullborg, Eva-Lena; Winberg, Anders

    2002-04-01

    The general objectives of the TRUE Block Scale Project were to 1) increase understanding of tracer transport in a fracture network and to improve predictive capabilities, 2) assess the importance of tracer retention mechanisms (diffusion and sorption) in a fracture network, and 3) assess the link between flow and transport data as a means for predicting transport phenomena. During the period mid 1996 through mid 1999 a 200x250x100 m rock volume was characterised with the purpose of furnishing the basis for successful tracer experiments in a network of conductive structures in the block scale (10-100 m). In total five cored boreholes were drilled as part of the project in an iterative mode with a period of analysis following completion of characterisation, and with a strong component of inter activity with numerical modelling and experimental design, particularly towards the end of the characterisation. The combined use of pressure responses due to drilling and drilling records provided important early information/confirmation of the existence and location of a given structure. Verification of conductors identified from pressure responses was achieved through the use of various flow logging techniques. The usage of the Posiva difference flow log towards the end of the characterisation work enabled identification of discrete conductive fractures with a high resolution. Pressure responses collected during drilling were used to obtain a first assessment of connectivity between boreholes. The transient behaviour of the responses collected during cross-hole interference tests in packed-off boreholes were used to identify families of responses, which correlated well with the identified principal families of structures/fracture networks. The conductive geometry of the investigated rock block is made up of steeply dipping deterministic NW structures and NNW structures. High inflows in the boreholes were for the most part associated with geologically/geometrically identified

  19. PUFKEY: a high-security and high-throughput hardware true random number generator for sensor networks.

    Science.gov (United States)

    Li, Dongfang; Lu, Zhaojun; Zou, Xuecheng; Liu, Zhenglin

    2015-10-16

    Random number generators (RNG) play an important role in many sensor network systems and applications, such as those requiring secure and robust communications. In this paper, we develop a high-security and high-throughput hardware true random number generator, called PUFKEY, which consists of two kinds of physical unclonable function (PUF) elements. Combined with a conditioning algorithm, true random seeds are extracted from the noise on the start-up pattern of SRAM memories. These true random seeds contain full entropy. Then, the true random seeds are used as the input for a non-deterministic hardware RNG to generate a stream of true random bits with a throughput as high as 803 Mbps. The experimental results show that the bitstream generated by the proposed PUFKEY can pass all standard national institute of standards and technology (NIST) randomness tests and is resilient to a wide range of security attacks.

  20. PUFKEY: A High-Security and High-Throughput Hardware True Random Number Generator for Sensor Networks

    Directory of Open Access Journals (Sweden)

    Dongfang Li

    2015-10-01

    Full Text Available Random number generators (RNG play an important role in many sensor network systems and applications, such as those requiring secure and robust communications. In this paper, we develop a high-security and high-throughput hardware true random number generator, called PUFKEY, which consists of two kinds of physical unclonable function (PUF elements. Combined with a conditioning algorithm, true random seeds are extracted from the noise on the start-up pattern of SRAM memories. These true random seeds contain full entropy. Then, the true random seeds are used as the input for a non-deterministic hardware RNG to generate a stream of true random bits with a throughput as high as 803 Mbps. The experimental results show that the bitstream generated by the proposed PUFKEY can pass all standard national institute of standards and technology (NIST randomness tests and is resilient to a wide range of security attacks.

  1. The impairment of true glomerular filtration rate in long-term cyclosporine-treated pediatric allograft recipients

    International Nuclear Information System (INIS)

    McDiarmid, S.V.; Ettenger, R.B.; Hawkins, R.A.; Senguttvan, P.; Busuttil, R.W.; Vargas, J.; Berquist, W.E.; Ament, M.E.

    1990-01-01

    We performed indium-111-DTPA plasma clearance studies in 61 pediatric kidney and liver recipients treated with cyclosporine to compare true glomerular filtration rate with calculated GFR (cGFR). The mean true GFR of 61.9 +/- 36.6 ml/min/1.73 m2 indicated renal impairment. The mean cGFR of 85.2 +/- 22.4 ml/min/1.73 m2 was significantly higher (P less than 0.001), and overestimated GFR by 38%. cGFR alone did not accurately reflect the degree of renal dysfunction. A group of 48 pediatric orthotopic liver transplant recipients was studied in more detail: 73% of these patients had a true GFR less than 70 ml/min/1.73 m2, while 85% had a true GFR below 90 ml/min/1.73 m2, the lower limit for normal GFR in children. The mean true GFR for patients treated more than 24 months with CsA was lower (P = 0.02) than patients treated with CsA for 12 to 24 months. OLT patients with normal true GFR (greater than 90 ml/min/1.73 m2) had significantly lower plasma CsA levels, and 50% of patients with a true GFR less than or equal to 50 ml/min/1.73 m2 had hypertension. There was no effect on true GFR of age, liver function, azathioprine use, or peritransplant treatment with other nephrotoxic drugs. We conclude that true GFR is significantly impaired in long-term CsA-treated allograft pediatric recipients. Calculations of GFR underestimate the degree of renal dysfunction. As patients treated greater than 24 months had the lowest true GFRs, the fall in GFR may be progressive

  2. The impact of sleep on true and false memory across long delays.

    Science.gov (United States)

    Pardilla-Delgado, Enmanuelle; Payne, Jessica D

    2017-01-01

    While the influence of sleep on memory has a long history, sleep's role in the formation of false memories is less clear. Moreover, virtually nothing is known about the development of false memories beyond delays of about 12h. Here, for the first time, we assess post-sleep development of true and false memories across longer delay intervals of 24 and 48h. Although technically a false memory, remembering information that is related to the theme, or gist, of an experience can be considered an adaptive process. Some evidence suggests that sleep, compared to a wake period, increases both true and gist-based false memories in the Deese-Roediger-McDermott (DRM) task, but not all studies have returned this result, and most studies cannot rule out the possibility that sleep is merely protecting the information from interference, as opposed to actively aiding its consolidation. Here, to equate amount of time spent awake and asleep across groups, we assess how the positioning of sleep relative to memory encoding impacts retention across longer delays of 24 and 48h. Participants encoded 16 DRM lists in the morning (WAKE 1st Groups) or evening (SLEEP 1st Groups), and were tested either 24 or 48h later at the same time of day. Results demonstrate that true memory is better when participants sleep soon after learning. Sleeping first also increased false memory, but only in low performers. Importantly, and similar to previous studies, we found a negative correlation between slow-wave sleep (SWS) and false memory, suggesting that SWS may be detrimental for semantic/gist processing. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Absolute plate motions and true polar wander in the absence of hotspot tracks.

    Science.gov (United States)

    Steinberger, Bernhard; Torsvik, Trond H

    2008-04-03

    The motion of continents relative to the Earth's spin axis may be due either to rotation of the entire Earth relative to its spin axis--true polar wander--or to the motion of individual plates. In order to distinguish between these over the past 320 Myr (since the formation of the Pangaea supercontinent), we present here computations of the global average of continental motion and rotation through time in a palaeomagnetic reference frame. Two components are identified: a steady northward motion and, during certain time intervals, clockwise and anticlockwise rotations, interpreted as evidence for true polar wander. We find approximately 18 degrees anticlockwise rotation about 250-220 Myr ago and the same amount of clockwise rotation about 195-145 Myr ago. In both cases the rotation axis is located at about 10-20 degrees W, 0 degrees N, near the site that became the North American-South American-African triple junction at the break-up of Pangaea. This was followed by approximately 10 degrees clockwise rotation about 145-135 Myr ago, followed again by the same amount of anticlockwise rotation about 110-100 Myr ago, with a rotation axis in both cases approximately 25-50 degrees E in the reconstructed area of North Africa and Arabia. These rotation axes mark the maxima of the degree-two non-hydrostatic geoid during those time intervals, and the fact that the overall net rotation since 320 Myr ago is nearly zero is an indication of long-term stability of the degree-two geoid and related mantle structure. We propose a new reference frame, based on palaeomagnetism, but corrected for the true polar wander identified in this study, appropriate for relating surface to deep mantle processes from 320 Myr ago until hotspot tracks can be used (about 130 Myr ago).

  4. Identification of distinct layers within the stratified squamous epithelium of the adult human true vocal fold.

    Science.gov (United States)

    Dowdall, Jayme R; Sadow, Peter M; Hartnick, Christopher; Vinarsky, Vladimir; Mou, Hongmei; Zhao, Rui; Song, Phillip C; Franco, Ramon A; Rajagopal, Jayaraj

    2015-09-01

    A precise molecular schema for classifying the different cell types of the normal human vocal fold epithelium is lacking. We hypothesize that the true vocal fold epithelium has a cellular architecture and organization similar to that of other stratified squamous epithelia including the skin, cornea, oral mucosa, and esophagus. In analogy to disorders of the skin and gastrointestinal tract, a molecular definition of the normal cell types within the human vocal fold epithelium and a description of their geometric relationships should serve as a foundation for characterizing cellular changes associated with metaplasia, dysplasia, and cancer. Qualitative study with adult human larynges. Histologic sections of normal human laryngeal tissue were analyzed for morphology (hematoxylin and eosin) and immunohistochemical protein expression profile, including cytokeratins (CK13 and CK14), cornified envelope proteins (involucrin), basal cells (NGFR/p75), and proliferation markers (Ki67). We demonstrated that three distinct cell strata with unique marker profiles are present within the stratified squamous epithelium of the true vocal fold. We used these definitions to establish that cell proliferation is restricted to certain cell types and layers within the epithelium. These distinct cell types are reproducible across five normal adult larynges. We have established that three layers of cells are present within the normal adult stratified squamous epithelium of the true vocal fold. Furthermore, replicating cell populations are largely restricted to the parabasal strata within the epithelium. This delineation of distinct cell populations will facilitate future studies of vocal fold regeneration and cancer. N/A. © 2015 The American Laryngological, Rhinological and Otological Society, Inc.

  5. Determination of true digestible amino acids of feedstuffs utilizing cecectomized roosters

    Directory of Open Access Journals (Sweden)

    Eliane Aparecida da Silva

    2012-09-01

    Full Text Available The objective of this study was to estimate the true digestibility coefficients of amino acids and digestible amino acid values of some poultry feedstuffs. The feedstuffs were: babassu meal, sunflower meal, corn gluten meal, babassu starchy meal, meat and bone meal, common beans, pearl millet and residues of cookies, pasta and bread. The precise feeding method of Sibbald was used with adult cecectomized Leghorn roosters distributed in a completely randomized design, consisting of ten treatments and six replications with a rooster in each. The treatments were represented by the feedstuffs evaluated. The roosters were kept in a period of fasting for 36 hours and then fed 30 grams of feed. Samples were collected during 56 hours. Simultaneously, six roosters were kept fasting to make corrections to the metabolic and endogenous losses of amino acids. At the end of collections, the excreta obtained were weighed, freeze-dried and subsequently processed, so laboratory analyses were carried out and the coefficients of true digestibility of amino acids were determined. The mean values of the coefficients of true digestibility of essential and non-essential amino acids in percentage were respectively: 0.702 and 0.652 for the babassu meal; 0.852 and 0.786 for the sunflower meal; 0.928 and 0.887 for the corn gluten meal; 0.797 and 0.720 for the meat and bone meal; 0.364 and 0.339 for ground raw beans; 0.924 and 0.837 for ground pearl millet; 0.839 and 0.810 for cookie residue; 0.929 and 0.914 for pasta residue; and 0.904 and 0.899 for bread residue.

  6. High precision instrumentation for measuring the true exposure time in diagnostic X-ray examinations

    International Nuclear Information System (INIS)

    Silva, Danubia B.; Santos, Marcus A.P.; Barros, Fabio R.; Santos, Luiz A.P.

    2013-01-01

    One of the most important physical quantities to be evaluated in diagnostic radiology is the radiation exposure time experimented by the patient during the X-ray examination. IAEA and WHO organizations have suggested that any country must create a quality surveillance program to verify if each type of ionizing radiation equipment used in the hospitals and medical clinics are in conformity with the accepted uncertainties following the international standards. The purpose of this work is to present a new high precision methodology for measuring true exposure time in diagnostic X-ray examinations: pulsed, continuous or digital one. An electronic system named CronoX, which will be soon registered at the Brazilian Patent Office (INPI), is the equipment that provides such a high precision measurement. The principle of measurement is based on the electrical signal captured by a sensor that enters in a regeneration amplifier to transform it in a digital signal, which is treated by a microprocessor (uP). The signal treatment results in a two measured times: 1) T rx , the true X-ray exposure time; 2) T nx , the time in which the X-ray machine is repeatedly cut off during the pulsed irradiation and there is no delivery dose to the patient. Conventional Polymat X-ray equipment and dental X-ray machines were used to generate X-ray photons and take the measurements with the electronic systems. The results show that such a high precision instrumentation displays the true exposure time in diagnostic X-ray examinations and indicates a new method to be purposed for the quality surveillance programs in radiology. (author)

  7. Studies of solar magnetic fields. V. The true average field strengths near the poles

    Energy Technology Data Exchange (ETDEWEB)

    Howard, R [Hale Observatories, Pasadena, Calif. (USA)

    1977-05-01

    An estimate of the average magnetic field strength at the poles of the Sun from Mount Wilson measurements is made by comparing low latitude magnetic measurements in the same regions made near the center of the disk and near the limb. There is still some uncertainty because the orientation angle of the field lines in the meridional plane is unknown, but the most likely possibility is that the true average field strengths are about twice the measured values (0-2 G), with an absolute upper limit on the underestimation of the field strengths of about a factor 5. The measurements refer to latitudes below about 80/sup 0/.

  8. A Reactive and Cycle-True IP Emulator for MPSoC Exploration

    DEFF Research Database (Denmark)

    Mahadevan, Shankar; Angiolini, Federico; Sparsø, Jens

    2008-01-01

    The design of MultiProcessor Systems-on-Chip (MPSoC) emphasizes intellectual-property (IP)-based communication-centric approaches. Therefore, for the optimization of the MPSoC interconnect, the designer must develop traffic models that realistically capture the application behavior as executing...... on the IP core. In this paper, we introduce a Reactive IP Emulator (RIPE) that enables an effective emulation of the IP-core behavior in multiple environments, including bit and cycle-true simulation. The RIPE is built as a multithreaded abstract instruction-set processor, and it can generate reactive...

  9. True posterior communicating artery aneurysms: are they more prone to rupture? A biomorphometric analysis.

    Science.gov (United States)

    He, Wenzhuan; Hauptman, Jason; Pasupuleti, Latha; Setton, Avi; Farrow, Maria G; Kasper, Lydia; Karimi, Reza; Gandhi, Chirag D; Catrambone, Jeffrey E; Prestigiacomo, Charles J

    2010-03-01

    Posterior communicating artery (PCoA) aneurysms can occur at the junction with the internal carotid artery, posterior cerebral artery (PCA), or the proximal PCoA itself. Hemodynamic stressors contribute to aneurysm formation and may be associated with parent vessel size and aneurysm location. This study evaluates the correlation of various biomorphometric characteristics in 2 of the aforementioned types of PCoA aneurysms. Patients with PCoA aneurysms were analyzed using CT angiography. Source images and reconstructions were used to determine which aneurysms originated purely from the PCoA and those that originated from the internal carotid artery/PCoA junction. Morphometric analysis was performed on the aneurysm, the precommunicating segment of the PCA (P(1)), the ambient segment of the PCA (P(2)), and both PCoA arteries and were correlated to clinical presentation. Parametric and nonparametric analyses were performed to test for significance. A total of 77 PCoA aneurysms were analyzed, and 10 were found to be true PCoA aneurysms (13.0%). The ipsilateral PCoA/P(1) ratio (1.77 +/- 0.44 vs 0.82 +/- 0.46, p = 0.0001) and ipsilateral P(2)/P(1) ratio (1.73 +/- 0.40 vs 1.22 +/- 0.41, p = 0.0003) were significantly larger in true PCoA aneurysms. Interestingly, aneurysm size was statistically larger in the junctional aneurysms (0.14 +/- 0.1 vs 0.072 +/- 0.04 cm(3), p = 0.03). The prevalence of ruptured aneurysms was similar in both groups (approximately 80%, p value not significant). These data suggest that true PCoA aneurysms have a larger PCoA relative to the ipsilateral P(1) segment. To the authors' knowledge, this represents the first such biomorphometric comparison of these different types of PCoA aneurysms. Although statistically smaller in size, true PCoA aneurysms also have a similar prevalence of presenting as a ruptured aneurysm, suggesting that they might be more prone to rupture than a junctional aneurysms of similar size. Further analysis will be required to

  10. Electromagnetic guided couch and multileaf collimator tracking on a TrueBeam accelerator

    DEFF Research Database (Denmark)

    Hansen, Rune; Ravkilde, Thomas; Worm, Esben Schjødt

    2016-01-01

    Purpose: Couch and MLC tracking are two promising methods for real-time motion compensation during radiation therapy. So far, couch and MLC tracking experiments have mainly been performed by different research groups, and no direct comparison of couch and MLC tracking of volumetric modulated arc...... to characterize the geometric and dosimetric performance of electromagnetic guided couch and MLC tracking on a TrueBeam accelerator equipped with a Millennium MLC. The tracking system latency was determined without motion prediction as the time lag between sinusoidal target motion and the compensating motion...

  11. A complicated true sliding hernia presenting as a spontaneous enteroscrotal fistula in an adult

    Directory of Open Access Journals (Sweden)

    Rajamanickam Saravana

    2010-01-01

    Full Text Available A 26-year-old man presented with an irreducible right inguino-scrotal swelling and fecal discharge from the scrotum. Exploratory laparotomy and inguinal exploration revealed that the caecum, appendix, and terminal ileum had herniated into the scrotum and had perforated through the skin forming a fecal fistula. The herniated gangrenous bowel was resected and a stoma fashioned. Spontaneous entero-scrotal fistulae are very rare and eight pediatric cases have been mentioned in literature till date. We report the first case of true sliding hernia presenting as spontaneous entero-scrotal fistula in an adult.

  12. THE FAIR VALUE OF AUTHENTIC AND TRUE METHOD OF ASSESSING THE LIABILITIES OF THE COMPANY

    Directory of Open Access Journals (Sweden)

    S. Travinska

    2013-11-01

    Full Text Available The article explores the nature of the category “assessment” in the scientific literature and normative documents; considered the types of assessments in the domestic and international practice; the methodology to assess the fair value of liabilities in accordance with IFRS; recommended methods for assessment of certain types of current liabilities accounting. Also the author describes the case for the use of different systems assessments of reflection of economic operations of the company. Defined the essence and necessity of application of the fair value in respect of the liabilities that would provide a true assessment of the financial condition of the enterprise and rational management accounting.

  13. Robot off-line programming and simulation as a true CIME-subsystem

    DEFF Research Database (Denmark)

    Nielsen, L.F; Trostmann, S; Trostmann, Erik

    1992-01-01

    A robot off-line programming and real-time simulation system, ROPSIM, which is based on the neutral interface concept and features simulation of the dynamics of both the controller and robot arm, has been developed. To avoid dependency on dedicated robot models, ROPSIM is based on generic models...... describing the robot controller, robot arm geometry, and the robot and arm kinetics. The software was developed using the C++ programming language. The key modules are discussed. The system is a true computer-integrated manufacturing and engineering subsystem which facilitates the exchange and reuse of robot...... model definition data and robot program definition data with systems of other origin or different functionality...

  14. True to life English for adult learners : pre-intermediate : teacher's book

    CERN Document Server

    Gairns, Ruth

    1995-01-01

    True to Life is a five-level course for adults. To ensure a high level of motivation, the course focuses on contemporary themes, language and learning styles that are relevant to adult learners. The Starter level provides between 40 and 60 hours of class work. The other levels provide between 72 and 96 hours of class work, depending on the various options used. The range of extra materials (photocopiable worksheets, tests and videos) create a comprehensive and flexible teaching package. The ready-made lessons can be used as they stand, saving teacher time, or adapted using the optional activities suggested in the Teacher's Book.

  15. Alpha-event and surface characterisation in segmented true-coaxial HPGe detectors

    Energy Technology Data Exchange (ETDEWEB)

    Abt, I.; Garbini, L., E-mail: luciagarbini86@gmail.com.mpg.de; Gooch, C.; Irlbeck, S.; Liu, X.; Palermo, M.; Schulz, O.

    2017-06-21

    A detailed study of alpha interactions on the passivation layer on the end-plate of a true-coaxial high-purity germanium detector is presented. The observation of alpha events on such a surface indicates an unexpectedly thin so-called “effective dead layer” of less than 20 µm thickness. In addition, the influence of the metalisation close to the end-plate on the time evolution of the output pulses is discussed. The results indicate that alpha contamination can result in events which could be mistaken as signals for neutrinoless double beta decay and provide some guidance on how to prevent this.

  16. Proliferative, reparative, and reactive benign bone lesions that may be confused diagnostically with true osseous neoplasms.

    LENUS (Irish Health Repository)

    Wick, Mark R

    2014-01-01

    Diagnostic problems attending intraosseous and parosteal pseudoneoplastic lesions can be radiographic, or histological, or both. Proliferations in this category may contain cellular fibro-osseous or chondro-osseous tissues that are difficult to separate microscopically from those seen in various true neoplasms of the bones. This review considers the clinicopathologic features of fibrous dysplasia, benign fibro-osseous lesions of the jawbones, osteofibrous dysplasia, metaphyseal fibrous defect, giant-cell reparative granuloma, "brown tumor" of hyperparathyroidism, synovial chondrometaplasia, aneurysmal bone cyst, tumefactive chronic osteomyelitis, proliferative Paget disease, and polyvinylpyrrolidone storage disease of bone.

  17. True ternary fission and quasifission of superheavy nuclear systems

    Directory of Open Access Journals (Sweden)

    Greiner Walter

    2011-10-01

    Full Text Available We found that a true ternary fission with formation of a heavy third fragment (a new kind of radioactivity is quite possible for superheavy nuclei due to the strong shell effects leading to a three-body clusterization with the two doubly magic tin-like cores. The three-body quasifission process could be even more pronounced for giant nuclear systems formed in collisions of heavy actinide nuclei. In this case a three-body clusterization might be proved experimentally by detection of two coincident lead-like fragments in low-energy U+U collisions.

  18. Application of basic physics principles to clinical neuroradiology: differentiating artifacts from true pathology on MRI.

    Science.gov (United States)

    Hakky, Michael; Pandey, Shilpa; Kwak, Ellie; Jara, Hernan; Erbay, Sami H

    2013-08-01

    This article outlines artifactual findings commonly encountered in neuroradiologic MRI studies and offers clues to differentiate them from true pathology on the basis of their physical properties. Basic MR physics concepts are used to shed light on the causes of these artifacts. MRI is one of the most commonly used techniques in neuroradiology. Unfortunately, MRI is prone to image distortion and artifacts that can be difficult to identify. Using the provided case illustrations, practical clues, and relevant physical applications, radiologists may devise algorithms to troubleshoot these artifacts.

  19. Feedback-controlled diffusion: From self-trapping to true self-avoiding walks

    International Nuclear Information System (INIS)

    Schulz, B.M.; Trimper, S.; Schulz, M.

    2005-01-01

    We study the asymptotic behavior of a Brownian particle under the influence of a dynamical feedback by numerical simulations and analytical considerations. The feedback is controlled by a memory coupling of strength λ. Whereas a negative memory strength yields a true self avoiding walk, a positive memory leads to a self-trapping of the particle. The localization is manifested by a constant mean square displacement in the long time limit which appears after an initial diffusive regime. The probability distribution function of the trapping distance shows an exponential decay. The numerical simulations are compared with an analytical modeling

  20. Positive Predictive Value of True Bacteremia according to the Number of Positive Culture Sets in Adult Patients.

    Science.gov (United States)

    Kitaura, Tsuyoshi; Chikumi, Hiroki; Fujiwara, Hiromitsu; Okada, Kensaku; Hayabuchi, Tatsuya; Nakamoto, Masaki; Takata, Miyako; Yamasaki, Akira; Igishi, Tadashi; Burioka, Naoto; Shimizu, Eiji

    2014-12-01

    Performing multiple blood culture sets simultaneously is a standard blood culture methodology, although it is often difficult to distinguish true bacteremia from contamination when only one of several blood culture sets is positive. This study clarified the relationship between the number of positive blood culture sets and clinical significance in patients with positive blood culture. Patients aged 18 years and over with at least 1 positive blood culture were enrolled. Positive blood culture episodes were categorized from clinical records as true bacteremia, contamination, or unknown clinical significance. The associations among episodes of true bacteremia, isolated bacteria, the number of positive blood culture sets from among the performed sets, and the clinical background of patients were analyzed. Among a total of 407 episodes, 262, 67 and 78 were true bacteremia, contamination and unknown clinical significance, respectively. The positive predictive values (PPVs) of 1 out of 1, 1 out of 2 and 2 out of 2 positive sets in cases of Staphylococcus aureus, were 81.3%, 50% and 100% respectively; those in cases of coagulase-negative Staphylococci were 20.5%, 10.8% and 63.5%, respectively. Almost all cases of Escherichia coli, Pseudomonas aeruginosa, Klebsiella species and Candida species were true bacteremia. The probability of true bacteremia was strongly associated with recent surgery in multivariate analysis (P sets from among the performed sets varies by microorganism. Therefore, PPVs calculated using this method may help physicians distinguish true bacteremia from contamination.

  1. True-and-error models violate independence and yet they are testable

    Directory of Open Access Journals (Sweden)

    Michael H. Birnbaum

    2013-11-01

    Full Text Available Birnbaum (2011 criticized tests of transitivity that are based entirely on binary choice proportions. When assumptions of independence and stationarity (iid of choice responses are violated, choice proportions could lead to wrong conclusions. Birnbaum (2012a proposed two statistics (correlation and variance of preference reversals to test iid, using random permutations to simulate p-values. Cha, Choi, Guo, Regenwetter, and Zwilling (2013 defended methods based on marginal proportions but conceded that such methods wrongly diagnose hypothetical examples of Birnbaum (2012a. However, they also claimed that ``true and error'' models also satisfy independence and also fail in such cases unless they become untestable. This article presents correct true-and-error models; it shows how these models violate iid, how they might correctly identify cases that would be misdiagnosed by marginal proportions, and how they can be tested and rejected. This note also refutes other arguments of Cha et al. (2013, including contentions that other tests failed to violate iid ``with flying colors'', that violations of iid ``do not replicate'', that type I errors are not appropriately estimated by the permutation method, and that independence assumptions are not critical to interpretation of marginal choice proportions.

  2. The effect of cognitive load on hemispheric asymmetries in true and false memory.

    Science.gov (United States)

    Tat, Michael J; Azuma, Tamiko

    2016-01-01

    Studies examining hemispheric asymmetries in false memory have shown that the right hemisphere (RH) is more susceptible to false memories compared to the left hemisphere (LH). Theories suggest that hemispheric asymmetries in true and false memory may be due to differences in representational coding and the use of top-down mechanisms in each hemisphere. In the current study, the Deese-Roediger-McDermott false memory paradigm was used in conjunction with divided visual field presentation to examine the role of top-down mechanisms in hemispheric asymmetries of true and false memory. In Experiment 1, participants studied lists of related words while completing secondary cognitive load tasks. In Experiment 2, the secondary tasks were administered during memory retrieval instead of memory encoding. Results revealed that cognitive loads imposed during the study phase influenced veridical memory in the LH more than the RH, but cognitive loads imposed during retrieval did not influence veridical memory in either hemisphere. Surprisingly, false memory rates were not influenced by cognitive loads and were higher in the LH. These data provide evidence that, at least for veridical memory, top-down control mechanisms are used more readily for the encoding of information into memory in the LH compared to the RH.

  3. "That never happened": adults' discernment of children's true and false memory reports.

    Science.gov (United States)

    Block, Stephanie D; Shestowsky, Donna; Segovia, Daisy A; Goodman, Gail S; Schaaf, Jennifer M; Alexander, Kristen Weede

    2012-10-01

    Adults' evaluations of children's reports can determine whether legal proceedings are undertaken and whether they ultimately lead to justice. The current study involved 92 undergraduates and 35 laypersons who viewed and evaluated videotaped interviews of 3- and 5-year-olds providing true or false memory reports. The children's reports fell into the following categories based on a 2 (event type: true vs. false) × 2 (child report: assent vs. denial) factorial design: accurate reports, false reports, accurate denials, and false denials. Results revealed that adults were generally better able to correctly judge accurate reports, accurate denials, and false reports compared with false denials: For false denials, adults were, on average, "confident" that the event had not occurred, even though the event had in fact been experienced. Participant age predicted performance. These findings underscore the greater difficulty adults have in evaluating young children's false denials compared with other types of reports. Implications for law-related situations in which adults are called upon to evaluate children's statements are discussed. PsycINFO Database Record (c) 2012 APA, all rights reserved.

  4. Can Implicit Associations Distinguish True and False Eyewitness Memory? Development and Preliminary Testing of the IATe.

    Science.gov (United States)

    Helm, Rebecca K; Ceci, Stephen J; Burd, Kayla A

    2016-11-01

    Eyewitness identification has been shown to be fallible and prone to false memory. In this study we develop and test a new method to probe the mechanisms involved in the formation of false memories in this area, and determine whether a particular memory is likely to be true or false. We created a seven-step procedure based on the Implicit Association Test to gauge implicit biases in eyewitness identification (the IATe). We show that identification errors may result from unconscious bias caused by implicit associations evoked by a given face. We also show that implicit associations between negative attributions such as guilt and eyewitnesses' final pick from a line-up can help to distinguish between true and false memory (especially where the witness has been subject to the suggestive nature of a prior blank line-up). Specifically, the more a witness implicitly associates an individual face with a particular crime, the more likely it is that a memory they have for that person committing the crime is false. These findings are consistent with existing findings in the memory and neuroscience literature showing that false memories can be caused by implicit associations that are outside conscious awareness. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  5. Not strange but not true: self-reported interest in a topic increases false memory.

    Science.gov (United States)

    O'Connell, Anthony; Greene, Ciara M

    2017-09-01

    People are more likely to recall both true and false information that is consistent with their pre-existing stereotypes, schemata and desires. In addition, experts in a particular field are more likely to experience false memory in relation to their area of expertise. Here, we investigate whether level of interest, as distinct from level of knowledge, and in the absence of self-professed expertise, is associated with increased false memory. 489 participants were asked to rank 7 topics from most to least interesting. They were then asked if they remembered the events described in four news items related to the topic they selected as the most interesting and four items related to the topic selected as least interesting. In each case, three of the events depicted had really happened and one was fictional. A high level of interest in a topic increased true memories for the topic and doubled the frequency of false memories, even after controlling for level of knowledge. We interpret the results in the context of the source-monitoring framework and suggest that false memories arise as a result of interference from existing information stored in domain-related schemata.

  6. Evaluation of the True Wavefront Aberrations in Eyes Implanted With a Rotationally Asymmetric Multifocal Intraocular Lens.

    Science.gov (United States)

    Akondi, Vyas; Pérez-Merino, Pablo; Martinez-Enriquez, Eduardo; Dorronsoro, Carlos; Alejandre, Nicolás; Jiménez-Alfaro, Ignacio; Marcos, Susana

    2017-04-01

    Standard evaluation of aberrations from wavefront slope measurements in patients implanted with a rotationally asymmetric multifocal intraocular lens (IOL), the Lentis Mplus (Oculentis GmbH, Berlin, Germany), results in large magnitude primary vertical coma, which is attributed to the intrinsic IOL design. The new proposed method analyzes aberrometry data, allowing disentangling the IOL power pupillary distribution from the true higher order aberrations of the eye. The new method of wavefront reconstruction uses retinal spots obtained at both the near and far foci. The method was tested using ray tracing optical simulations in a computer eye model virtually implanted with the Lentis Mplus IOL, with a generic cornea or with anterior segment geometry obtained from custom quantitative spectral-domain optical coherence tomography in a real patient. The method was applied to laser ray tracing aberrometry data at near and far fixation obtained in a patient implanted with the Lentis Mplus IOL. Higher order aberrations evaluated from simulated and real retinal spot diagrams following the new reconstruction approach matched the nominal aberrations (approximately 98%). Previously reported primary vertical coma in patients implanted with this IOL lost significance with the application of the proposed reconstruction. Custom analysis of ray tracing-based retinal spot diagrams allowed decoupling of the true higher order aberrations of the patient's eye from the power pupillary distribution of a rotationally asymmetric multifocal IOL, therefore providing the appropriate phase map to accurately evaluate through-focus optical quality. [J Refract Surg. 2017;33(4):257-265.]. Copyright 2017, SLACK Incorporated.

  7. Neuromorphic Kalman filter implementation in IBM’s TrueNorth

    Science.gov (United States)

    Carney, R.; Bouchard, K.; Calafiura, P.; Clark, D.; Donofrio, D.; Garcia-Sciveres, M.; Livezey, J.

    2017-10-01

    Following the advent of a post-Moore’s law field of computation, novel architectures continue to emerge. With composite, multi-million connection neuromorphic chips like IBM’s TrueNorth, neural engineering has now become a feasible technology in this novel computing paradigm. High Energy Physics experiments are continuously exploring new methods of computation and data handling, including neuromorphic, to support the growing challenges of the field and be prepared for future commodity computing trends. This work details the first instance of a Kalman filter implementation in IBM’s neuromorphic architecture, TrueNorth, for both parallel and serial spike trains. The implementation is tested on multiple simulated systems and its performance is evaluated with respect to an equivalent non-spiking Kalman filter. The limits of the implementation are explored whilst varying the size of weight and threshold registers, the number of spikes used to encode a state, size of neuron block for spatial encoding, and neuron potential reset schemes.

  8. Effects of Vehicle Weight and True Versus Indicated Airspeed on BVI Noise During Steady Descending Flight

    Science.gov (United States)

    Stephenson, James H.; Greenwood, Eric

    2015-01-01

    Blade-vortex interaction noise measurements are analyzed for an AS350B helicopter operated at 7000 ft elevation above sea level. Blade-vortex interaction (BVI) noise from four, 6 degree descent conditions are investigated with descents flown at 80 knot true and indicated airspeed, as well as 4400 and 3915 pound take-off weights. BVI noise is extracted from the acquired acoustic signals by way of a previously developed time-frequency analysis technique. The BVI extraction technique is shown to provide a better localization of BVI noise, compared to the standard Fourier transform integration method. Using this technique, it was discovered that large changes in BVI noise amplitude occurred due to changes in vehicle gross weight. Changes in BVI noise amplitude were too large to be due solely to changes in the vortex strength caused by varying vehicle weight. Instead, it is suggested that vehicle weight modifies the tip-path-plane angle of attack, as well as induced inflow, resulting in large variations of BVI noise. It was also shown that defining flight conditions by true airspeed, rather than indicated airspeed, provides more consistent BVI noise signals.

  9. Posthumous Humans, Modern Vampires: Re-use, seriality, chorality of horror tropes in True Blood

    Directory of Open Access Journals (Sweden)

    Giulia Iannuzzi

    2016-06-01

    Full Text Available Why are some of us – inhabitants of increasingly dense and complex narrative ecosystems – compulsive spectators of horrors? What determines the liveliness of horror tropes that already have a long history of being used and re-used in narratives across different media, and what favors their being used incessantly on the small screen? This essay argues that in analyzing contemporary television series, we need to takes into account specific productive and narrative aspects, and (intra- and inter-textual elements as well as sociological ones, starting from the theoretical assumption that the fortune of horror series (and not only of them is in fact determined by those territories where these elements come together. As a case in point, this essay takes a look at True Blood, which was created in 2008 for HBO by Alan Ball, and came to an end with its seventh season in 2014. Positioned within the broader context of horror proliferation in contemporary television series, True Blood offers striking examples of the new mechanisms and distinction practices utilized by the television genre which is bringing about an increasing differentiation of audience segment.

  10. Fully decentralized control of a soft-bodied robot inspired by true slime mold.

    Science.gov (United States)

    Umedachi, Takuya; Takeda, Koichi; Nakagaki, Toshiyuki; Kobayashi, Ryo; Ishiguro, Akio

    2010-03-01

    Animals exhibit astoundingly adaptive and supple locomotion under real world constraints. In order to endow robots with similar capabilities, we must implement many degrees of freedom, equivalent to animals, into the robots' bodies. For taming many degrees of freedom, the concept of autonomous decentralized control plays a pivotal role. However a systematic way of designing such autonomous decentralized control system is still missing. Aiming at understanding the principles that underlie animals' locomotion, we have focused on a true slime mold, a primitive living organism, and extracted a design scheme for autonomous decentralized control system. In order to validate this design scheme, this article presents a soft-bodied amoeboid robot inspired by the true slime mold. Significant features of this robot are twofold: (1) the robot has a truly soft and deformable body stemming from real-time tunable springs and protoplasm, the former is used for an outer skin of the body and the latter is to satisfy the law of conservation of mass; and (2) fully decentralized control using coupled oscillators with completely local sensory feedback mechanism is realized by exploiting the long-distance physical interaction between the body parts stemming from the law of conservation of protoplasmic mass. Simulation results show that this robot exhibits highly supple and adaptive locomotion without relying on any hierarchical structure. The results obtained are expected to shed new light on design methodology for autonomous decentralized control system.

  11. The True Seed of Shalott (TSS Technology Production on Trisula Variety in East Java

    Directory of Open Access Journals (Sweden)

    P.E.R. Prahardini

    2018-01-01

    Full Text Available One of the onion increasing production problem is the lack of quality seeds availability. In order to provide high quality seeds of high yield and available throughout the year, an improvement of seed technology is required. One of the developing onion seed technologies is onion seeding through TSS (true seed of shallot. TSS technology development is expected to overcome the problem of onion seeding in Indonesia. East Java as one of the production centers of onion requires in developing onion seeding technology through TSS. This study aims to apply and develop TSS production technology using Trisula varieties which has been done from April to December 2016 in Tulungrejo village, Bumiaji district, Batu. The result of TSS production technology implementation indicates that Trisula variety is able to produce 110,5 kg TSS. Based on its agro-ecology, Batu area has the potential as the center of TSS production in East Java. Keywords: Onion, Technology, Trisula Varieties, True Seed of Shalot

  12. Time-reversed ultrasonically encoded (TRUE) focusing for deep-tissue optogenetic modulation

    Science.gov (United States)

    Brake, Joshua; Ruan, Haowen; Robinson, J. Elliott; Liu, Yan; Gradinaru, Viviana; Yang, Changhuei

    2018-02-01

    The problem of optical scattering was long thought to fundamentally limit the depth at which light could be focused through turbid media such as fog or biological tissue. However, recent work in the field of wavefront shaping has demonstrated that by properly shaping the input light field, light can be noninvasively focused to desired locations deep inside scattering media. This has led to the development of several new techniques which have the potential to enhance the capabilities of existing optical tools in biomedicine. Unfortunately, extending these methods to living tissue has a number of challenges related to the requirements for noninvasive guidestar operation, speed, and focusing fidelity. Of existing wavefront shaping methods, time-reversed ultrasonically encoded (TRUE) focusing is well suited for applications in living tissue since it uses ultrasound as a guidestar which enables noninvasive operation and provides compatibility with optical phase conjugation for high-speed operation. In this paper, we will discuss the results of our recent work to apply TRUE focusing for optogenetic modulation, which enables enhanced optogenetic stimulation deep in tissue with a 4-fold spatial resolution improvement in 800-micron thick acute brain slices compared to conventional focusing, and summarize future directions to further extend the impact of wavefront shaping technologies in biomedicine.

  13. True Detective Stories: Media Textuality and the Anthology Format between Remediation and Transmedia Narratives

    Directory of Open Access Journals (Sweden)

    Cristina Demaria

    2014-12-01

    Full Text Available Through the analysis of the recent HBO first season TV series True Detective (2014-, the essays focuses on the renewed anthology format of contemporary seriality as a way to inscribe the form of the novel in the transmedia imagination and its narrative models. While the first part of the essay concentrates on Media and Literary Studies’ debates on the statute of media texts, their materiality and the transformations of their contents in the participatory and convergent culture of prosumers, the second part is devoted to an in-depth reading of some of the main features of True Detective’s first season: from the ways it remediates many other genres and media, to how – as an audiovisual sychretyc text -  it plays with dialogues, cinematography, music and its temporal, spatial and seeing enunciative strategies and positions in order to construct a (quasidystopic narrative of America as an after-image, or, better, a post-collapse America and its Southern Gothic landscapes. In the lst paragraph, this writing briefly engages with how this particular format of TV series helps developing narrative models that fan we bpages and fanfic archives are still struggling not so much to comprehend, but to actually transform into an expanded textuality  able to tell a more ‘true’ story.

  14. Low cost anaerobic system for Indonesia: single baffled septic tank.

    Science.gov (United States)

    Wibisono, G; Mathew, K; Ho, Goen

    2003-01-01

    The insertion of a single baffle into a laboratory septic tank to mix incoming feed with sludge has been shown to improve anaerobic degradation of the feed. This is particularly true of soluble organic matter such as glucose. Oil or cellulose fed separately does not undergo degradation. It is expected however that a balanced feed such as sewage will be better degraded.

  15. A framework for assessing the concordance of molecular typing methods and the true strain phylogeny of Campylobacter jejuni and C. coli using draft genome sequence data

    Directory of Open Access Journals (Sweden)

    Catherine Dianna Carrillo

    2012-05-01

    Full Text Available Tracking of sources of sporadic cases of campylobacteriosis remains challenging, as commonly used molecular typing methods have limited ability to unambiguously link genetically related strains. Genomics has become increasingly prominent in the public health response to enteric pathogens as methods enable characterization of pathogens at an unprecedented level of resolution. However, the cost of sequencing and expertise required for bioinformatic analyses remains prohibitive, and these comprehensive analyses are limited to a few priority strains. Although several molecular typing methods are currently widely used for epidemiological analysis of campylobacters, it is not clear how accurately these methods reflect true strain relationships. To address this, we analyzed 104 publically available whole genome sequences (WGS of C. jejuni and C. coli. In addition to in silico determination of multi-locus sequence (MLST, fla and porA type, as well as comparative genomic fingerprint (CGF, we inferred a reference phylogeny based on conserved core genome elements. Molecular typing data were compared to the reference phylogeny for concordance using the Adjusted Wallace Coefficient (AWC with confidence intervals. Although MLST targets the sequence variability in core genes and CGF targets insertions/deletions of accessory genes, both methods are based on multilocus analysis and provided better estimates of true phylogeny than methods based on single loci (porA, fla. A more comprehensive WGS dataset including additional genetically related strains, both epidemiologically linked and unlinked, will be necessary to assess performance of methods for outbreak investigations and surveillance activities. Analyses of the strengths and weaknesses of widely used typing methodologies in inferring true strain relationships will provide guidance in the interpretation of this data for epidemiological purposes.

  16. Superficial Dorsal Venous Rupture of the Penis: False Penile Fracture That Needs to be Treated as a True Urologic Emergency.

    Science.gov (United States)

    Truong, Hong; Ferenczi, Basil; Cleary, Ryan; Healy, Kelly A

    2016-11-01

    A 38-year-old man with history of repaired penile fracture presented with rapid detumescence, penile pain, and ecchymosis during vaginal sexual intercourse concerning for recurrent fracture. Surgical exploration revealed ruptured superficial dorsal vein of the penis, which was subsequently ligated. Patients with traumatic penile vascular injuries often present with clinical features indistinguishable from a true penile fracture. Gradual detumescence and an absence of characteristic popping sound may indicate a vascular injury but they cannot safely rule out a true penile fracture. Both true and false penile fractures require emergent surgical exploration and repair to prevent long-term complications. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Sampling strategies to capture single-cell heterogeneity

    OpenAIRE

    Satwik Rajaram; Louise E. Heinrich; John D. Gordan; Jayant Avva; Kathy M. Bonness; Agnieszka K. Witkiewicz; James S. Malter; Chloe E. Atreya; Robert S. Warren; Lani F. Wu; Steven J. Altschuler

    2017-01-01

    Advances in single-cell technologies have highlighted the prevalence and biological significance of cellular heterogeneity. A critical question is how to design experiments that faithfully capture the true range of heterogeneity from samples of cellular populations. Here, we develop a data-driven approach, illustrated in the context of image data, that estimates the sampling depth required for prospective investigations of single-cell heterogeneity from an existing collection of samples. ...

  18. Modeling of transmission and DLG factors for a TrueBeam STX; Modelagem dos fatores de transmissão e DLG para um TrueBeam STX

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Laís B.; Pavan, Guilherme A.; Camargo, André V.; Santoni, Letícia M.; Silva, Diego C. S. A. [Hospital de Câncer de Barretos, SP (Brazil)

    2017-07-01

    For the rounded leaf-end Multi Leaf Collimator (MLC), the Eclipse planning system (Varian) requires the measurement of the Transmission Factor (FT) and Dosimetric Leaf Gap (DLG) for Intensity Modulated Radiation Therapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT). The use of these factors obtained by the methodology proposed by Varian may not guarantee the best agreement in quality assurance (QA) of patients, while the modeling of these factors makes it possible to obtain an 'optimal' value by reducing the differences between doses measured / calculated. The objective of this work was to measure the FT and DLG of a TrueBeam accelerator (TB) with different setups and detectors, model these parameters and validate the results applying the AAPM-TG119 methodology using the Portal Dosimetry (PD) system. To obtain FT and DLG (6MV, 6FFF, 10MV and 10FFF), DICOM plans supplied by Varian and Farmer ionization chamber and CC13 were used in different setups. For the modeling, the dose measured with the Farmer chamber was initially used in VMAT plans for prostate and head and neck. From the obtained data, interactively the values of the FT and DLG were altered by searching for a higher oil index (> 95%) in the 1% 1mm criterion using the PD. Finally, all planning of TG119 with IMRT and VMAT were measured using PD. The measured values were: 6X [(FT = 1.1% / 1.0%) (DLG = 0.044cm / 0.12cm)], 10X [(FT = 1.3% / 1.3% (FT = 0.93% / 0.4%) (DLG = 0.036cm / 0.05cm)], 10FFF [(FT = 1.14% / 1.05%) (DLG = 0.048 Cm / 0.05cm)]. The mean acceptance percentages for the gamma criterion 1% 1mm of the TG119 schedules with VMAT / IMRT after modeling were 6X: 96% / 76%; 10X: 98% / 95%; 6FFF: 97% / 87%; 10FFF: 97% / 82%. The modeling of FT and DLG is useful to improve the accuracy of patient quality assurance, but the choice of detector and the technique used (VMAT or IMRT) are determinant and lead to different results. A balance should be found according to the routine of the

  19. Lower Cambrian-Ediacaran Paleogeography and True Polar Wander with New Paleomagnetic Constraints from West African Craton

    Science.gov (United States)

    Robert, B.; Besse, J.; Blein, O.; Greff-Lefftz, M.; Baudin, T.; Fernando, L.; Meslouh, S.; Belbadaoui, M.

    2014-12-01

    Paleomagnetic data from Laurentia and Baltica continents suggest fast large oscillations of the virtual geomagnetic poles (VGP) from high to low latitudes during the Ediacaran (635-542 Ma). These data are interpreted in the literature either as oscillations of the Earth magnetic dipole between polar and equatorial positions, or as True Polar Wander (TPW), implying a very fast tumbling of continents and perhaps, of whole Earth. In this study, we try to test these hypotheses by bringing new paleomagnetic data on volcanic series from another continent, the West African Craton (WAC). We have sampled well dated pyroclastic and lava flows from the Ouarzazate and Taroudant groups in the Anti-Atlas, (Morocco). 480 samples from 105 sites were thermally demagnetized in our laboratory. Our preliminary results highlight two major groups of directions, mainly carried by hematite, magnetite also contributing sometimes to the magnetization. The first group consists of a dual polarity high inclination direction that may represent the original magnetization. The observed paleolatitude is compatible with that predicted by the lower Cambrian-Ediacaran apparent polar wander path (APWP) of Gondwana, assuming that the WAC was already accreted to Gondwana at this age. Nevertheless, a complete agreement between our pole and the APWP needs a local rotation of around 80° on a vertical axis. The second group displays a single polarity direction, with a shallow inclination and a south-east declination. This direction is close to the expected direction derived from the Permo-Carboniferous segment of the Gondwana APWP, and may represent a remagnetization acquired during the Kiaman reversed polarity superchron. Our preliminary paleomagnetic results thus display large changes in the VGP position, as also evidenced by others on Baltica and Laurentia. However, their interpretation does not favor TPW episodes or equatorial Earth magnetic dipole during the lower Cambrian-Ediacaran periods, but

  20. A Study Regarding the Possibility of True Polar Wander on the Asteroid Vesta

    Science.gov (United States)

    Karimi, M.; Dombard, A. J.

    2014-12-01

    The asteroid 4 Vesta, with an average diameter of ~525 km, is the second most massive asteroid in the solar system. Most of our knowledge about this differentiated asteroid comes from the Howardite-Eucrite-Diogenite class of meteorites that originated from Vesta, images provided by Hubble Space Telescope, and data from the Dawn spacecraft that orbited Vesta from July 2011 to September 2012. Notably, these close-range data confirmed what Hubble images suggested: a highly oblate shape in which the equatorial radius is ~60 km greater than the polar radius, a shape consistent with Vesta's short rotational period of ~5.3 hr. These images also revealed the presence of two large impact craters near the asteroid's south pole. Rheasilvia, the younger and larger crater at ~500 km in diameter, is superimposed over Veneneia, ~400 km in diameter. The occurrence of two large impacts near a pole, which possesses a relatively small area (less than 30% of the surface), is highly improbable. Thus, we investigate the possibility of True Polar Wander. We hypothesize that the integrated mass deficit of these two basins applied a torque to the lithosphere to reorient the surface relative to the spin axis and thereby placing these basins near the pole. In order for this phenomenon to occur, however, the lithosphere needs to be pliable enough to allow relaxation of the ancient rotational bulge and concurrent development of the current bulge. We have previously explored whether the lithosphere of Vesta could support the large-scale (~20 vertical km) topography of the basins (short answer: it can). Here, we explore whether this lithosphere could also permit True Polar Wander. We use the Finite Element Method and a viscoelastic rheology to simulate the relaxation of an oblate Vesta under a range of plausible thermal scenarios consistent with Vesta's expected budget of long-lived radiogenic nuclides. Our results indicate that under reasonable thermal conditions, the relaxation of the

  1. Measurement of true ileal digestibility of phosphorus in some feed ingredients for broiler chickens.

    Science.gov (United States)

    Mutucumarana, R K; Ravindran, V; Ravindran, G; Cowieson, A J

    2014-12-01

    An experiment was conducted to estimate the true ileal digestibility of P in wheat, sorghum, soybean meal, and corn distiller's dried grains with solubles (DDGS) in broiler chickens. Four semipurified diets were formulated from each ingredient (wheat and sorghum: 236.5, 473, 709.5, and 946 g/kg; soybean meal and corn DDGS: 135, 270, 405, and 540 g/kg) to contain graded concentrations of nonphytate P. The experiment was conducted as a randomized complete block design with 4 weight blocks of 16 cages each (5 birds per cage). A total of 320 21-d-old broilers (Ross 308) were assigned to the 16 test diets with 4 replicates per diet. Apparent ileal digestibility coefficients of P were determined by the indicator method and the linear regression method was used to determine the true P digestibility coefficients. The results showed that the apparent ileal P digestibility coefficients of wheat-based diets were not influenced (P>0.05) by increasing dietary P concentrations, whereas those of diets based on sorghum, soybean meal, and corn DDGS differed (Pdigestibility in broilers fed diets with soybean meal and corn DDGS linearly (Pdigestibility coefficients of wheat, sorghum, soybean meal, and corn DDGS were determined to be 0.464, 0.331, 0.798, and 0.727, respectively. Ileal endogenous P losses in birds fed diets with wheat, soybean meal, and corn DDGS were estimated to be 0.080, 0.609, and 0.418 g/kg DMI, respectively. In birds fed sorghum-based diets, endogenous P losses were estimated to be negative (-0.087 g/kg DMI). True digestible P contents of wheat, sorghum, soybean meal, and corn DDGS were determined to be 1.49, 0.78, 5.16, and 5.94 g/kg, respectively. The corresponding nonphytate P contents in wheat, sorghum, soybean meal, and corn DDGS were 1.11, 0.55, 2.15, and 4.36 g/kg, respectively. These differences between digestible P and nonphytate P contents may be suggestive, at least in part, of overestimation of P digestibility under the calcium-deficient conditions

  2. A three-dimensional `Kaiser damage-memory' effect through true-triaxial loading

    Science.gov (United States)

    Meredith, P. G.; Browning, J.; Harland, S. R.; Healy, D.; Stuart, C.; Mitchell, T. M.

    2017-12-01

    Microcrack damage leading to failure in rocks evolves in response to differential loading. The vast majority of experimental studies investigate damage evolution, the `Kaiser damage-memory' effect, and rock failure using conventional triaxial stress states (σ1 > σ2 = σ3). Such stress states develop a crack population that displays cylindrical transverse isotropy. However, in nature the stress state is in general truly triaxial (σ1 > σ2 > σ3) and experiments that utilise such loading conditions can generate crack populations that display planar transverse isotropy which in turn influences properties such as permeability and strength. We investigate the evolution of crack damage under both conventional and true triaxial stress conditions using results from measurements made on cubic samples of sandstone deformed in three orthogonal directions with independently controlled stress paths. We have measured, simultaneously with stress and strain, the changes in ultrasonic compressional and shear wave velocities in the three principal directions, together with the bulk acoustic emission (AE) output. Changes in acoustic wave velocities are associated with both elastic closure and opening of pre-existing cracks, and the inelastic formation of new cracks. By contrast, AE is only associated with the inelastic growth of new crack damage and as such, we use the onset of AE to determine the initiation of new crack damage. By mapping these damage onsets under both conventional triaxial and true triaxial sequential cyclic loading, we have shown that `damage envelopes' evolve dynamically and can be pushed closer to the failure envelope. Whether a stress state has been `visited' before is key to determining and understanding damage states. Crack damage populations can be generated with multiple orientations depending on the arrangement of loading directions and hence principal stress directions. The sequential cyclic loading tests show that further damage in any one population

  3. Free to be me: The relationship between the true self, rejection sensitivity, and use of online dating sites.

    Science.gov (United States)

    Hance, Margaret A; Blackhart, Ginette; Dew, Megan

    2018-01-01

    Prior research (Blackhart et al., 2014) found that rejection-sensitive individuals are more likely to use online dating sites. The purpose of the current research was to explain the relationship between rejection sensitivity and online dating site usage. Study 1 examined whether true self mediated the relation between rejection sensitivity and online dating. Study 2 sought to replicate the findings of Study 1 and to examine whether self-disclosure moderated the relationship between true self and online dating in the mediation model. Results replicated those found by Blackhart et al. and also found that true self mediated the relationship between rejection sensitivity and online dating site usage. These findings suggest that rejection-sensitive individuals feel they can more easily represent their "true" selves in online environments, such as online dating sites, which partially explains why they are more likely to engage in online dating.

  4. Integrated High-Speed Digital Optical True-Time-Delay Modules for Synthetic Aperture Radars, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Crystal Research, Inc. proposes an integrated high-speed digital optical true-time-delay module for advanced synthetic aperture radars. The unique feature of this...

  5. Broadband true time delay for microwave signal processing, using slow light based on stimulated Brillouin scattering in optical fibers.

    Science.gov (United States)

    Chin, Sanghoon; Thévenaz, Luc; Sancho, Juan; Sales, Salvador; Capmany, José; Berger, Perrine; Bourderionnet, Jérôme; Dolfi, Daniel

    2010-10-11

    We experimentally demonstrate a novel technique to process broadband microwave signals, using all-optically tunable true time delay in optical fibers. The configuration to achieve true time delay basically consists of two main stages: photonic RF phase shifter and slow light, based on stimulated Brillouin scattering in fibers. Dispersion properties of fibers are controlled, separately at optical carrier frequency and in the vicinity of microwave signal bandwidth. This way time delay induced within the signal bandwidth can be manipulated to correctly act as true time delay with a proper phase compensation introduced to the optical carrier. We completely analyzed the generated true time delay as a promising solution to feed phased array antenna for radar systems and to develop dynamically reconfigurable microwave photonic filters.

  6. Volumetric analysis demonstrates that true and false lumen remodeling persists for 12 months after thoracic endovascular aortic repair

    Directory of Open Access Journals (Sweden)

    Ga-Young Suh, PhD

    2016-09-01

    Full Text Available A 62-year-old man underwent an elephant trunk procedure followed by thoracic endovascular aortic repair (TEVAR. Computed tomography angiography-based models were built to quantify volume of the whole aorta and true and false lumens preoperatively, before TEVAR, after TEVAR, and at follow-up at 3, 6, and 12 months. With TEVAR, descending aortic true lumen volume increased by 54%, then increased additionally by 60% during 12 months. The descending aortic false lumen volume regressed continuously for 12 months following TEVAR, with the most rapid rate from 6 to 12 months at 16 cm3/month. TEVAR immediately increased true lumen volume and continued to remodel the true and false lumens throughout the following 12 months.

  7. True coincidence summing correction determination for 214Bi principal gamma lines in NORM samples

    International Nuclear Information System (INIS)

    Haddad, Kh.

    2014-01-01

    The gamma lines 609.3 and 1,120.3 keV are two of the most intensive γ emissions of 214 Bi, but they have serious true coincidence summing (TCS) effects due to the complex decay schemes with multi-cascading transitions. TCS effects cause inaccurate count rate and hence erroneous results. A simple and easy experimental method for determination of TCS correction of 214 Bi gamma lines was developed in this work using naturally occurring radioactive material samples. Height efficiency and self attenuation corrections were determined as well. The developed method has been formulated theoretically and validated experimentally. The corrections problems were solved simply with neither additional standard source nor simulation skills. (author)

  8. Identity, transcendence and the true self: Insights from psychology and contemplative spirituality

    Directory of Open Access Journals (Sweden)

    Carter Haynes

    2016-11-01

    Full Text Available This article investigates the intersection of psychology and spirituality as seen through the works of Thomas Merton, Carl Jung, Fritz Kunkel and Viktor Frankl. The themes of spirituality contextualised in human identity, psychological and spiritual transcendence, and the true self versus false self metaphor are traced through the works of all four thinkers. Epistemological flexibility and holistic thinking and being are suggested as methods for transforming interdisciplinary practitioners, such as pastoral counsellors, spiritual directors and spiritually oriented psychotherapists, in order that they can offer care in a less bifurcated and more integrated way. Practical applications, including a vignette and specific recommendations for broadening and deepening personal and professional integrative practice, are offered.

  9. True Nature of Supply Network Communication Structure (P.1-14

    Directory of Open Access Journals (Sweden)

    Lokhman Hakim bin Osman

    2017-02-01

    Full Text Available Globalization of world economy has altered the definition of organizational structure. Global supply chain can no longer be viewed as an arm-length structure. It has become more complex. The complexity demands deeper research and understanding. This research analyzed a structure of supply network in an attempt to elucidate the true structure of the supply network. Using the quantitative Social Network Analysis methodology, findings of this study indicated that, the structure of the supply network differs depending on the types of network relations. An important implication of these findings would be a more focus resource management upon network relationship development that is based on firms’ positions in the different network structure. This research also contributes to the various strategies of effective and efficient supply chain management.Keywords: Supply Chain Management, Network Studies, Inter-Organizational Relations, Social Capital

  10. True random number generation from mobile telephone photo based on chaotic cryptography

    International Nuclear Information System (INIS)

    Zhao Liang; Liao Xiaofeng; Xiao Di; Xiang Tao; Zhou Qing; Duan Shukai

    2009-01-01

    A cheap, convenient and universal TRNG based on mobile telephone photo for producing random bit sequence is proposed. To settle the problem of sequential pixels and comparability, three chaos-based approaches are applied to post-process the generated binary image. The random numbers produced by three users are tested using US NIST RNG statistical test software. The experimental results indicate that the Arnold cat map is the fastest way to generate a random bit sequence and can be accepted on general PC. The 'MASK' algorithm also performs well. Finally, comparing with the TRNG of Hu et al. [Hu Y, Liao X, Wong KW, Zhou Q. A true random number generator based on mouse movement and chaotic cryptography. Chaos, Solitons and Fractals 2007. doi: 10.1016/j.chaos.2007.10.022] which is presented by Hu et al., many merits of the proposed TRNG in this paper has been found.

  11. Mapping Rural Areas with Widespread Plastic Covered Vineyards Using True Color Aerial Data

    Directory of Open Access Journals (Sweden)

    Eufemia Tarantino

    2012-06-01

    Full Text Available Plastic covering is used worldwide to protect crops against damaging growing conditions. This agricultural practice raises some controversial issues. While it significantly impacts on local economic vitality, plasticulture also shows several environmental affects. In the Apulia Region (Italy the wide-spreading of artificial plastic coverings for vineyard protection has showed negative consequences on the hydrogeological balance of soils as well as on the visual quality of rural landscape. In order to monitor and manage this phenomenon, a detailed site mapping has become essential. In this study an efficient object-based classification procedure from Very High Spatial Resolution (VHSR true color aerial data was developed on eight test areas located in the Ionian area of the Apulia Region in order to support the updating of the existing land use database aimed at plastic covered vineyard monitoring.

  12. True density and apparent density during the drying process for vegetables and fruits: a review.

    Science.gov (United States)

    Rodríguez-Ramírez, J; Méndez-Lagunas, L; López-Ortiz, A; Torres, S Sandoval

    2012-12-01

    This review presents the concepts involved in determining the density of foodstuffs, and summarizes the volumetric determination techniques used to calculate true density and apparent density in foodstuffs exposed to the drying process. The behavior of density with respect to moisture content (X) and drying temperature (T) is presented and explained with a basis in changes in structure, conformation, chemical composition, and second-order phase changes that occur in the processes of mass and heat transport, as reported to date in the literature. A review of the empirical and theoretical equations that represent density is presented, and their application in foodstuffs is discussed. This review also addresses cases with nonideal density behavior, including variations in ρ(s) and ρ(w) as a function of the inside temperature of the material, depending on drying conditions (X, T). A compilation of studies regarding the density of dehydrated foodstuffs is also presented. © 2012 Institute of Food Technologists®

  13. Mitochondrial phylogenomics of Hemiptera reveals adaptive innovations driving the diversification of true bugs

    Science.gov (United States)

    Li, Hu; Leavengood, John M.; Chapman, Eric G.; Burkhardt, Daniel; Song, Fan; Jiang, Pei; Liu, Jinpeng; Cai, Wanzhi

    2017-01-01

    Hemiptera, the largest non-holometabolous order of insects, represents approximately 7% of metazoan diversity. With extraordinary life histories and highly specialized morphological adaptations, hemipterans have exploited diverse habitats and food sources through approximately 300 Myr of evolution. To elucidate the phylogeny and evolutionary history of Hemiptera, we carried out the most comprehensive mitogenomics analysis on the richest taxon sampling to date covering all the suborders and infraorders, including 34 newly sequenced and 94 published mitogenomes. With optimized branch length and sequence heterogeneity, Bayesian analyses using a site-heterogeneous mixture model resolved the higher-level hemipteran phylogeny as (Sternorrhyncha, (Auchenorrhyncha, (Coleorrhyncha, Heteroptera))). Ancestral character state reconstruction and divergence time estimation suggest that the success of true bugs (Heteroptera) is probably due to angiosperm coevolution, but key adaptive innovations (e.g. prognathous mouthpart, predatory behaviour, and haemelytron) facilitated multiple independent shifts among diverse feeding habits and multiple independent colonizations of aquatic habitats. PMID:28878063

  14. High-speed true random number generation based on paired memristors for security electronics

    Science.gov (United States)

    Zhang, Teng; Yin, Minghui; Xu, Changmin; Lu, Xiayan; Sun, Xinhao; Yang, Yuchao; Huang, Ru

    2017-11-01

    True random number generator (TRNG) is a critical component in hardware security that is increasingly important in the era of mobile computing and internet of things. Here we demonstrate a TRNG using intrinsic variation of memristors as a natural source of entropy that is otherwise undesirable in most applications. The random bits were produced by cyclically switching a pair of tantalum oxide based memristors and comparing their resistance values in the off state, taking advantage of the more pronounced resistance variation compared with that in the on state. Using an alternating read scheme in the designed TRNG circuit, the unbiasedness of the random numbers was significantly improved, and the bitstream passed standard randomness tests. The Pt/TaO x /Ta memristors fabricated in this work have fast programming/erasing speeds of ˜30 ns, suggesting a high random number throughput. The approach proposed here thus holds great promise for physically-implemented random number generation.

  15. True and measured outgassing rates of a vacuum chamber with a reversibly adsorbed phase

    Energy Technology Data Exchange (ETDEWEB)

    Akaishi, K. [National Inst. for Fusion Science, Toki, Gifu (Japan); Nakasuga, M. [Graduate School of Energy Science, Kyoto Univ., Uji, Kyoto (Japan); Funato, Y. [Suzuka National College of Technology, Suzuka, Mie (Japan)

    2000-03-01

    A pump down model for a vacuum chamber with a reversibly adsorbed phase is presented. The outgassing equation which predicts the variation of coverage at the wall surface of a vacuum chamber with time is derived. Then the measured and the true outgassing rates are defined. The theoretical measured outgassing rate shows only a very weak dependence for pumping speed. This prediction is opposite to the experimental result that the measured outgassing rate depends significantly on pumping speed. It is discussed that the experimental measured outgassing rate must be described as the product of the effective pumping speed and the measured pressure in the pumped chamber, in which the measured pressure is equivalent to the equilibrium pressure of the wall surface described by the equilibrium adsorption isotherm as a function of the shifted surface coverage {theta}-{delta}{theta} by a small coverage {delta}{theta} from the coverage of a pumping point {delta}. (author)

  16. True and measured outgassing rates of a vacuum chamber with a reversibly adsorbed phase

    International Nuclear Information System (INIS)

    Akaishi, K.; Nakasuga, M.; Funato, Y.

    2000-03-01

    A pump down model for a vacuum chamber with a reversibly adsorbed phase is presented. The outgassing equation which predicts the variation of coverage at the wall surface of a vacuum chamber with time is derived. Then the measured and the true outgassing rates are defined. The theoretical measured outgassing rate shows only a very weak dependence for pumping speed. This prediction is opposite to the experimental result that the measured outgassing rate depends significantly on pumping speed. It is discussed that the experimental measured outgassing rate must be described as the product of the effective pumping speed and the measured pressure in the pumped chamber, in which the measured pressure is equivalent to the equilibrium pressure of the wall surface described by the equilibrium adsorption isotherm as a function of the shifted surface coverage θ-Δθ by a small coverage Δθ from the coverage of a pumping point Δ. (author)

  17. Estimating the Proportion of True Null Hypotheses in Multiple Testing Problems

    Directory of Open Access Journals (Sweden)

    Oluyemi Oyeniran

    2016-01-01

    Full Text Available The problem of estimating the proportion, π0, of the true null hypotheses in a multiple testing problem is important in cases where large scale parallel hypotheses tests are performed independently. While the problem is a quantity of interest in its own right in applications, the estimate of π0 can be used for assessing or controlling an overall false discovery rate. In this article, we develop an innovative nonparametric maximum likelihood approach to estimate π0. The nonparametric likelihood is proposed to be restricted to multinomial models and an EM algorithm is also developed to approximate the estimate of π0. Simulation studies show that the proposed method outperforms other existing methods. Using experimental microarray datasets, we demonstrate that the new method provides satisfactory estimate in practice.

  18. True coincidence summing corrections for an extended energy range HPGe detector

    Energy Technology Data Exchange (ETDEWEB)

    Venegas-Argumedo, Y. [Centro de Investigación en Materiales Avanzados (CIMAV), Miguel de Cervantes 120, Chihuahua, Chih 31109 (Mexico); M.S. Student at CIMAV (Mexico); Montero-Cabrera, M. E., E-mail: elena.montero@cimav.edu.mx [Centro de Investigación en Materiales Avanzados (CIMAV), Miguel de Cervantes 120, Chihuahua, Chih 31109 (Mexico)

    2015-07-23

    True coincidence summing (TCS) effect for natural radioactive families of U-238 and Th-232 represents a problem when an environmental sample with a close source-detector geometry measurement is performed. By using a certified multi-nuclide standard source to calibrate an energy extended range (XtRa) HPGe detector, it is possible to obtain an intensity spectrum slightly affected by the TCS effect with energies from 46 to 1836 keV. In this work, the equations and some other considerations required to calculate the TCS correction factor for isotopes of natural radioactive chains are described. It is projected a validation of the calibration, performed with the IAEA-CU-2006-03 samples (soil and water)

  19. No-Report Paradigms: Extracting the True Neural Correlates of Consciousness.

    Science.gov (United States)

    Tsuchiya, Naotsugu; Wilke, Melanie; Frässle, Stefan; Lamme, Victor A F

    2015-12-01

    The goal of consciousness research is to reveal the neural basis of phenomenal experience. To study phenomenology, experimenters seem obliged to ask reports from the subjects to ascertain what they experience. However, we argue that the requirement of reports has biased the search for the neural correlates of consciousness over the past decades. More recent studies attempt to dissociate neural activity that gives rise to consciousness from the activity that enables the report; in particular, no-report paradigms have been utilized to study conscious experience in the full absence of any report. We discuss the advantages and disadvantages of report-based and no-report paradigms, and ask how these jointly bring us closer to understanding the true neural basis of consciousness. Crown Copyright © 2015. Published by Elsevier Ltd. All rights reserved.

  20. Haemosuccus pancreaticus due to true splenic artery aneurysm: a rare cause of massive upper gastrointestinal bleeding

    Directory of Open Access Journals (Sweden)

    MK Roy

    2010-07-01

    Full Text Available “Haemosuccus pancreaticus” is an unusual cause of severe upper gastrointestinal bleeding and results from rupture of splenic artery aneurysm into the pancreatic duct. More commonly, it is a pseudoaneurysm of the splenic artery which develops as sequelae of pancreatitis. However, true aneurysm of the splenic artery without pancreatitis has rarely been incriminated as the etiologic factor of this condition. Owing to the paucity of cases and limited knowledge about the disease, diagnosis as well as treatment become challenging. Here we describe a 60-year-old male presenting with severe recurrent upper gastrointestinal bleeding and abdominal pain, which, after considerable delay, was diagnosed to be due to splenic artery aneurysm. Following an unsuccessful endovascular embolisation, the patient was cured by distal pancreatectomy and ligation of aneurysm.

  1. In search of the true universe the tools, shaping, and cost of cosmological thought

    CERN Document Server

    Harwit, Martin

    2013-01-01

    Astrophysicist and scholar Martin Harwit examines how our understanding of the cosmos advanced rapidly during the twentieth century and identifies the factors contributing to this progress. Astronomy, whose tools were largely imported from physics and engineering, benefited mid-century from the US policy of coupling basic research with practical national priorities. This strategy, initially developed for military and industrial purposes, provided astronomy with powerful tools yielding access - at virtually no cost - to radio, infrared, X-ray, and gamma-ray observations. Today, astronomers are investigating the new frontiers of dark matter and dark energy, critical to understanding the cosmos but of indeterminate socio-economic promise. Harwit addresses these current challenges in view of competing national priorities and proposes alternative new approaches in search of the true Universe. This is an engaging read for astrophysicists, policy makers, historians, and sociologists of science looking to learn and a...

  2. True strain-temperature diagram and structural aspects of molybdenum fracture

    International Nuclear Information System (INIS)

    Vasil'ev, A.D.; Gornaya, I.D.; Moiseev, V.F.; Pechkovskij, Eh.P.; Ponomarev, S.S.; Trefilov, V.I.

    1982-01-01

    For the purpose of studying the regularities of tough fracture of polycrystal molybdenum and explaining characteristic types of uniaxial tensile fractures in the 100-1000 deq C temperature range it is suggested for the first time to use the true strain-temperature (TST) diagram which combines a diagram of structural states and temperature dependence of a number of critical strains reflecting the dynamics of emergence and development of micro-non continuities in a tension specimen. It is shown that in the polycrystal molybdenum the basic parameters controlling the course and the magnitude of separate strain stages as well as the transition to fracture are the strain hardening coefficient and the elasticity limit relation to the strain hardening coefficient at the first stage (homoo.eneous dislocations distribution stage). The TST diagram permits also to explain the following phenomena: the nature of cold brittleness upper temperature, the observed change of fracture mechanisms with the temperature increase, the fracture surface origin

  3. Transparency of Accounting Information in Achieving Good Corporate Governance. True View and Fair Value

    Directory of Open Access Journals (Sweden)

    Mariana Man

    2016-05-01

    Full Text Available One of the key factors affecting the efficient use of resources, the increase of shareholders confidence in the managers of the company, the success in achieving objectives and economic efficiency is the system of corporate governance by which a company is managed and controlled. We cannot talk about a culture of corporate governance without thinking of the criteria of transparency, of responsibility in ensuring the accuracy of data from financial reports. Transparency is a prerequisite of good communication between the company and the interested parties. This paper examines the concepts of true image and fair value as premises of transparency of the accounting information in order to accomplish good corporate governance.

  4. Great apes distinguish true from false beliefs in an interactive helping task.

    Directory of Open Access Journals (Sweden)

    David Buttelmann

    Full Text Available Understanding the behavior of others in a wide variety of circumstances requires an understanding of their psychological states. Humans' nearest primate relatives, the great apes, understand many psychological states of others, for example, perceptions, goals, and desires. However, so far there is little evidence that they possess the key marker of advanced human social cognition: an understanding of false beliefs. Here we demonstrate that in a nonverbal (implicit false-belief test which is passed by human 1-year-old infants, great apes as a group, including chimpanzees (Pan troglodytes, bonobos (Pan paniscus, and orangutans (Pongo abelii, distinguish between true and false beliefs in their helping behavior. Great apes thus may possess at least some basic understanding that an agent's actions are based on her beliefs about reality. Hence, such understanding might not be the exclusive province of the human species.

  5. On the form of species–area relationships in habitat islands and true islands

    DEFF Research Database (Denmark)

    Matthews, Thomas J.; Guilhaumon, François; Triantis, Kostas A.

    2016-01-01

    and c vary between different island types. Location: Global. Methods: We used an information theoretic approach to compare the fit of 20 ISAR models to 207 habitat island datasets. Model performance was ranked according to pre-set criteria, including metrics of generality and efficiency. We also fitted......, and was the highest ranked model overall. In general, the more complex models performed badly. Average z-values were significantly lower for habitat island datasets than for true islands, and were higher for mountaintop and urban habitat islands than for other habitat island types. Average c-values were significantly...... multimodel comparisons demonstrated the nonlinear implementation of the power model to be the best overall model and thus to be a sensible choice for general use. As the z-value of the log–log power model varied in relation to ecological and geographical properties of the study systems, caution should...

  6. Large-Scale True Triaxial Apparatus for Geophysical Studies in Fractured Rock

    KAUST Repository

    Garcia, A. V.

    2018-05-12

    The study of fractured rock masses in the laboratory remains challenging because of the large specimen sizes and bulky loading systems that are required. This article presents the design, structural analysis, and operation of a compact and self-reacting true triaxial device for fractured rock. The frame subjects a 50 cm by 50 cm by 50 cm fractured rock specimen to a maximum stress of 3 MPa along three independent axes. Concurrent measurements include long-wavelength P-wave propagation, passive acoustic emission monitoring, deformations, and thermal measurements. The device can accommodate diverse research, from rock mass properties and geophysical fractured rock characterizations, to coupled hydro-chemo-thermo-mechanical processes, drilling, and grouting. Preliminary wave propagation data gathered under isotropic and anisotropic stress conditions for an assembly of 4,000 rock blocks demonstrate the system’s versatility and provide unprecedented information related to long-wavelength propagation in fractured rock under various stress anisotropies.

  7. Magnetic resonance imaging in the differential diagnosis of true placenta accreta: a clinical case

    Directory of Open Access Journals (Sweden)

    E. V. Tarachkova

    2016-01-01

    Full Text Available True placenta accreta is the attachment of chorionic villi to the myometrium, possibly penetrating into the thickness of the myometrium and its outside, including through the serous tunic. The main current diagnostic techniques are considered to be ultrasonography, laboratory diagnosis (elevated human chorionic gonadotropin and placental lactogen levels, and clinical data (pain and vaginal discharge. Magnetic resonance imaging is deemed to be an adjuvant technique. By using a clinical example, this paper considers the capabilities of magnetic resonance imaging to diagnose this abnormality and to choose a right treatment policy. The abnormality is compared with the conditions (trophoblastic tumor and myoma with lysis that are similar in their diagnosis and magnetic resonance pattern. The disorder in question is rather rare and its detailed consideration, determination of the capabilities of various techniques, and comparison with externally similar cases areimportant for the development of diagnostic opportunities.

  8. Subwavelength grating enabled on-chip ultra-compact optical true time delay line.

    Science.gov (United States)

    Wang, Junjia; Ashrafi, Reza; Adams, Rhys; Glesk, Ivan; Gasulla, Ivana; Capmany, José; Chen, Lawrence R

    2016-07-26

    An optical true time delay line (OTTDL) is a basic photonic building block that enables many microwave photonic and optical processing operations. The conventional design for an integrated OTTDL that is based on spatial diversity uses a length-variable waveguide array to create the optical time delays, which can introduce complexities in the integrated circuit design. Here we report the first ever demonstration of an integrated index-variable OTTDL that exploits spatial diversity in an equal length waveguide array. The approach uses subwavelength grating waveguides in silicon-on-insulator (SOI), which enables the realization of OTTDLs having a simple geometry and that occupy a compact chip area. Moreover, compared to conventional wavelength-variable delay lines with a few THz operation bandwidth, our index-variable OTTDL has an extremely broad operation bandwidth practically exceeding several tens of THz, which supports operation for various input optical signals with broad ranges of central wavelength and bandwidth.

  9. Large-Scale True Triaxial Apparatus for Geophysical Studies in Fractured Rock

    KAUST Repository

    Garcia, A. V.; Rached, R. M.; Santamarina, Carlos

    2018-01-01

    The study of fractured rock masses in the laboratory remains challenging because of the large specimen sizes and bulky loading systems that are required. This article presents the design, structural analysis, and operation of a compact and self-reacting true triaxial device for fractured rock. The frame subjects a 50 cm by 50 cm by 50 cm fractured rock specimen to a maximum stress of 3 MPa along three independent axes. Concurrent measurements include long-wavelength P-wave propagation, passive acoustic emission monitoring, deformations, and thermal measurements. The device can accommodate diverse research, from rock mass properties and geophysical fractured rock characterizations, to coupled hydro-chemo-thermo-mechanical processes, drilling, and grouting. Preliminary wave propagation data gathered under isotropic and anisotropic stress conditions for an assembly of 4,000 rock blocks demonstrate the system’s versatility and provide unprecedented information related to long-wavelength propagation in fractured rock under various stress anisotropies.

  10. Uncoupling proteins (UCP) in unicellular eukaryotes: true UCPs or UCP1-like acting proteins?

    Science.gov (United States)

    Luévano-Martínez, Luis Alberto

    2012-04-05

    Uncoupling proteins belong to the superfamily of mitochondrial anion carriers. They are apparently present throughout the Eukarya domain in which only some members have an established physiological function, i.e. UCP1 from brown adipose tissue is involved in non-shivering thermogenesis. However, the proteins responsible for the phenotype observed in unicellular organisms have not been characterized. In this report we analyzed functional evidence concerning unicellular UCPs and found that true UCPs are restricted to some taxonomical groups while proteins conferring a UCP1-like phenotype to fungi and most protists are the result of a promiscuous activity exerted by other mitochondrial anion carriers. We describe a possible evolutionary route followed by these proteins by which they acquire this promiscuous mechanism. Copyright © 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

  11. Prior-knowledge-based feedforward network simulation of true boiling point curve of crude oil.

    Science.gov (United States)

    Chen, C W; Chen, D Z

    2001-11-01

    Theoretical results and practical experience indicate that feedforward networks can approximate a wide class of functional relationships very well. This property is exploited in modeling chemical processes. Given finite and noisy training data, it is important to encode the prior knowledge in neural networks to improve the fit precision and the prediction ability of the model. In this paper, as to the three-layer feedforward networks and the monotonic constraint, the unconstrained method, Joerding's penalty function method, the interpolation method, and the constrained optimization method are analyzed first. Then two novel methods, the exponential weight method and the adaptive method, are proposed. These methods are applied in simulating the true boiling point curve of a crude oil with the condition of increasing monotonicity. The simulation experimental results show that the network models trained by the novel methods are good at approximating the actual process. Finally, all these methods are discussed and compared with each other.

  12. It Could Have Been True: How Counterfactual Thoughts Reduce Condemnation of Falsehoods and Increase Political Polarization.

    Science.gov (United States)

    Effron, Daniel A

    2018-05-01

    This research demonstrates how counterfactual thoughts can lead people to excuse others for telling falsehoods. When a falsehood aligned with participants' political preferences, reflecting on how it could have been true led them to judge it as less unethical to tell, which in turn led them to judge a politician who told it as having a more moral character and deserving less punishment. When a falsehood did not align with political preferences, this effect was significantly smaller and less reliable, in part because people doubted the plausibility of the relevant counterfactual thoughts. These results emerged independently in three studies (two preregistered; total N = 2,783) and in meta- and Bayesian analyses, regardless of whether participants considered the same counterfactuals or generated their own. The results reveal how counterfactual thoughts can amplify partisan differences in judgments of alleged dishonesty. I discuss implications for theories of counterfactual thinking and motivated moral reasoning.

  13. When true memory availability promotes false memory: evidence from confabulating patients.

    Science.gov (United States)

    Ciaramelli, Elisa; Ghetti, Simona; Frattarelli, Massimo; Làdavas, Elisabetta

    2006-01-01

    We explored the extent to which confabulators are susceptible to false recall and false recognition, and whether false recognition is reduced when memory for studied items is experimentally enhanced. Five confabulating patients, nine non-confabulating amnesics--including patients with (F amnesics) and without frontal-lobe dysfunction (NF amnesics)--and 14 control subjects underwent the DRM paradigm [Roediger, H. L., & McDermott, K. B. (1995). Creating false memories: Remembering words not presented in lists. Journal of Experimental Psychology: Learning, Memory and Cognition, 21, 803-814.] in two experimental conditions. In both conditions participants studied eight lists of semantic associates, and free recall was tested after the presentation of each list. In the Standard condition recognition was tested after the presentation of all the lists, whereas in the Proximal condition patients were administered a six-item recognition task after the presentation of each list. Participants also provided remember or know judgements, and described the content of their recollections. All groups of patients recalled a lower proportion of targets and critical lures than did control subjects, but confabulators recalled more words unrelated to the studied lists than did NF amnesics and controls. All groups of participants improved true recognition across conditions. However, whereas normal controls suppressed false recognition to critical lures in the Proximal compared to the Standard condition, and non-confabulating amnesics showed comparable gist-based false recognition, confabulators showed increased levels of false recognition to critical lures across conditions. Furthermore, NF amnesics significantly reduced false recognition to unrelated lures in the Proximal compared to the Standard condition, whereas confabulators were unable to suppress false recognition to unrelated lures across conditions. Analysis of the phenomenological experience showed that, unlike non

  14. SU-F-R-12: Prediction of TrueBeam Hardware Issues Using Trajectory Log Analysis

    Energy Technology Data Exchange (ETDEWEB)

    DiCostanzo, D; Ayan, A; Woollard, J; Gupta, N [The Ohio State University, Columbus, OH (United States)

    2016-06-15

    Purpose: To predict potential failures of hardware within the Varian TrueBeam linear accelerator in order to proactively replace parts and decrease machine downtime. Methods: Machine downtime is a problem for all radiation oncology departments and vendors. Most often it is the result of unexpected equipment failure, and increased due to lack of in-house clinical engineering support. Preventative maintenance attempts to assuage downtime, but often is ineffective at preemptively preventing many failure modes such as MLC motor failures, the need to tighten a gantry chain, or the replacement of a jaw motor, among other things. To attempt to alleviate downtime, software was developed in house that determines the maximum value of each axis enumerated in the Truebeam trajectory log files. After patient treatments, this data is stored in a SQL database. Microsoft Power BI is used to plot the average maximum error of each day of each machine as a function of time. The results are then correlated with actual faults that occurred at the machine with the help of Varian service engineers. Results: Over the course of six months, 76,312 trajectory logs have been written into the database and plotted in Power BI. Throughout the course of analysis MLC motors have been replaced on three machines due to the early warning of the trajectory log analysis. The service engineers have also been alerted to possible gantry issues on one occasion due to the aforementioned analysis. Conclusion: Analyzing the trajectory log data is a viable and effective early warning system for potential failures of the TrueBeam linear accelerator. With further analysis and tightening of the tolerance values used to determine a possible imminent failure, it should be possible to pinpoint future issues more thoroughly and for more axes of motion.

  15. Laparoscopic Heller myotomy for achalasia: changing trend toward "true" day-case procedure.

    Science.gov (United States)

    Agrawal, Sanjay; Super, Paul

    2008-12-01

    Laparoscopic Heller myotomy is the most effective therapy for achalasia. All case series have reported a minimum length of stay of more than 1 day. "True" day-case laparoscopic Heller myotomy has not been reported, so far. The aim of this study was to review our results with laparoscopic Heller myotomy with respect to the length of stay following the procedure. All patients undergoing laparoscopic Heller myotomy between August 2000 and July 2007 under the care of one surgeon were included in the study. This was performed by incising 6 cm of distal esophageal musculature, extending to 2 cm below the gastroesophageal junction. The myotomy was covered by an anterior fundoplication. All patients were reviewed in the clinic at a median of 6 weeks after surgery and, thereafter, if necessary. Over the 7-year period, 24 consecutive patients with achalasia were treated in this manner. There were 13 women and 11 men, with an age range of 12-73 years. Intraoperative complications included mucosal perforation in 2 patients (sutured immediately) with no postoperative complications or conversion to open surgery. There were no deaths. The average length of stay was 1.9 days (range, 0-4). The last 2 patients were discharged on the same day, and the 5 previous to this were discharged within 23 hours of surgery. There were no adverse outcomes related to early discharge, and there were no readmissions. All patients reported good to excellent results with a relief of dysphagia on follow-up. Three patients (12%) developed recurrent dysphagia after an initial improvement, requiring dilatation only several months later. Based on our own experience, we believe that laparoscopic Heller myotomy with anterior partial fundoplication is safe and achieves a good outcome in the treatment of achalasia. It is well tolerated and can be considered a true day-case procedure.

  16. SU-F-R-12: Prediction of TrueBeam Hardware Issues Using Trajectory Log Analysis

    International Nuclear Information System (INIS)

    DiCostanzo, D; Ayan, A; Woollard, J; Gupta, N

    2016-01-01

    Purpose: To predict potential failures of hardware within the Varian TrueBeam linear accelerator in order to proactively replace parts and decrease machine downtime. Methods: Machine downtime is a problem for all radiation oncology departments and vendors. Most often it is the result of unexpected equipment failure, and increased due to lack of in-house clinical engineering support. Preventative maintenance attempts to assuage downtime, but often is ineffective at preemptively preventing many failure modes such as MLC motor failures, the need to tighten a gantry chain, or the replacement of a jaw motor, among other things. To attempt to alleviate downtime, software was developed in house that determines the maximum value of each axis enumerated in the Truebeam trajectory log files. After patient treatments, this data is stored in a SQL database. Microsoft Power BI is used to plot the average maximum error of each day of each machine as a function of time. The results are then correlated with actual faults that occurred at the machine with the help of Varian service engineers. Results: Over the course of six months, 76,312 trajectory logs have been written into the database and plotted in Power BI. Throughout the course of analysis MLC motors have been replaced on three machines due to the early warning of the trajectory log analysis. The service engineers have also been alerted to possible gantry issues on one occasion due to the aforementioned analysis. Conclusion: Analyzing the trajectory log data is a viable and effective early warning system for potential failures of the TrueBeam linear accelerator. With further analysis and tightening of the tolerance values used to determine a possible imminent failure, it should be possible to pinpoint future issues more thoroughly and for more axes of motion.

  17. Use of general anaesthesia in paediatric dentistry: barriers to discriminate between true and false cases.

    Science.gov (United States)

    Aminabadi, N A; Najafpour, E; Aghaee, S; Sighari Deljavan, A; Jamali, Z; Shirazi, S

    2016-04-01

    The use of general anaesthesia (GA) has shown significant increase in child dental patients. This study aimed to assess whether behaviour management strategies can be the effective methods for decreasing the need for GA and its over-utilisation in paediatric dentistry. The patients (n = 240) aged 3-6 years old were selected from referrals by paediatric dentists (PD) or general dentists (GD) for dental treatment under GA. Each child's behaviour during first and subsequent appointments was assessed using the Frankl Behaviour Rating Scale. A first visit included clinical examination and fluoride therapy. In all sessions, a hierarchy of anxiety-reducing behaviour guidance strategies was implemented over nine steps in a logical treatment order. Overall, 47.5% of children referred for dental treatments under GA were retrained to be treated routinely. False referrals were significantly higher in GD compared to PD group. 80.0% of the referred children by PD and 6.7% of those referred by GD were true GA cases and still needed GA. 20.1% of retrained children and 67.4% of true GA cases received conscious sedation. There was no significant change in the frequency of children considered uncooperative as the years of experience increased among GD, while this value was significant for PD. The findings may highlight the importance of using behaviour management techniques thoroughly prior to referring an uncooperative child for treatment under GA, and may discourage its over-utilisation. Specifically, these skill sets and their efficient practice should be improved among general dentists.

  18. Fluctuating confidence: the dynamic consequences of true/false affirmatives and denials on how a listener appraises their personal past.

    Science.gov (United States)

    Davis, Jolee; Bayantemur, Sharon Y; Seecharan, Sasha; Unger, Leslie D; Hellgren, Johanna; Stone, Charles B

    2018-08-01

    The present study examined the mnemonic consequences of true/false denials and affirmatives on how a listener appraises their personal past. To this end, participants (listeners) rated the extent to which they were confident certain events occurred during their childhood. They rated these events both before and after a confederate (speaker) denied or affirmed the occurrence of four different childhood events each, for a total of eight "rehearsed" events. For each set (denials and affirmatives) of events, half were true and half were false. In turn, this created four types of events (two each): true denials, true affirmatives, false denials, and false affirmatives. Additionally, half of the participants were told that the speaker was provided independent information about the veracity of the event's occurrence ("expert" condition). Overall, listeners were less confident in the occurrence of false denial events, but more so when they believed the speaker to be more knowledgeable of the listeners memories, more confident in false affirmative events and, counter intuitively, more confident in the occurrence of true denial events. These results underscore the importance of a nuanced approach to the mnemonic consequences of true and false denials and affirmations in the course of social interactions.

  19. Experimental characterization of true spontaneous emission rate of optically-pumped InGaAs/GaAs quantum-well laser structure

    Directory of Open Access Journals (Sweden)

    Q.-N. Yu

    2017-08-01

    Full Text Available In this paper, an experimental approach to acquiring true spontaneous emission rate of optically-pumped InGaAs/GaAs quantum-well laser structure is described. This method is based on a single edge-emitting laser chip with simple sample processing. The photoluminescence spectra are measured at both facets of the edge-emitting device and transformed to the spontaneous emission rate following the theory described here. The unusual double peaks appearing in the spontaneous emission rate spectra are observed for the InGaAs/GaAs quantum-well structure. The result is analyzed in terms of Indium-rich island and Model-Solid theories. The proposed method is suitable for electrically-pumped quantum-well laser structures, as well.

  20. Evaluation of Operator Performance Using True Color and Artificial Color in Natural Scene Perception

    National Research Council Canada - National Science Library

    Vargo, John

    1999-01-01

    .... Recent advances in technology have permitted the fusion of the output of these two devices into a single color display that potentially combines the capabilities of both sensors while overcoming their limitations...

  1. Solid-state single-photon emitters

    Science.gov (United States)

    Aharonovich, Igor; Englund, Dirk; Toth, Milos

    2016-10-01

    Single-photon emitters play an important role in many leading quantum technologies. There is still no 'ideal' on-demand single-photon emitter, but a plethora of promising material systems have been developed, and several have transitioned from proof-of-concept to engineering efforts with steadily improving performance. Here, we review recent progress in the race towards true single-photon emitters required for a range of quantum information processing applications. We focus on solid-state systems including quantum dots, defects in solids, two-dimensional hosts and carbon nanotubes, as these are well positioned to benefit from recent breakthroughs in nanofabrication and materials growth techniques. We consider the main challenges and key advantages of each platform, with a focus on scalable on-chip integration and fabrication of identical sources on photonic circuits.

  2. Evaluation of the portal veins, hepatic veins and bile ducts using fat-suppressed segmented True FISP

    International Nuclear Information System (INIS)

    Ueda, Takashi; Uchikoshi, Masato; Imaoka, Izumi; Iwaya, Kazuo; Matsuo, Michimasa; Wada, Akihiko

    2005-01-01

    True FISP (fast imaging with steady-state free precession) is a fast imaging technique that provides high SNR (signal to noise ratio) and excellent delineation of parenchymal organs. The contrast of True FISP depends on the mixture of T 2 /T 1 . Vessels with slow flow are usually displayed as high signal intensity on True FISP images. The purpose of this study was to optimize fat-suppressed (FS) segmented True FISP imaging for portal veins, hepatic veins, and bile ducts. FS segmented True FISP images were applied to the phantoms of liver parenchyma, saline, and oil with various flip angles (every 10 degrees from 5-65 degrees) and k-space segmentations (3, 15, 25, 51, 75, 99). Five healthy volunteers were also examined to get optimized flip angle and k-space segmentation. The largest flip angle, 65 degrees, showed the best contrast between the liver parenchyma phantom, saline, and oil. The largest segmentations, 99, provided the best contrast between a liver parenchyma phantom and saline. However, the signal of the oil phantom exceeded that of the liver parenchyma phantom with 99 segmentations. As a result, the flip angle of 65 degrees and 75 segments is recommended to get the best contrast between the liver parenchyma phantom and saline, while suppressing the signal of oil. The volunteer studies also support the phantom studies and showed excellent anatomical delineation of portal veins, hepatic veins, and bile ducts when using these parameters. We conclude that True FISP is potentially suitable for the imaging of portal veins, hepatic veins, and bile ducts. The flip angle of 65 degrees with 75 segments is recommended to optimize FS segmented True FISP images. (author)

  3. SU-E-T-327: The Update of a XML Composing Tool for TrueBeam Developer Mode

    International Nuclear Information System (INIS)

    Yan, Y; Mao, W; Jiang, S

    2014-01-01

    Purpose: To introduce a major upgrade of a novel XML beam composing tool to scientists and engineers who strive to translate certain capabilities of TrueBeam Developer Mode to future clinical benefits of radiation therapy. Methods: TrueBeam Developer Mode provides the users with a test bed for unconventional plans utilizing certain unique features not accessible at the clinical mode. To access the full set of capabilities, a XML beam definition file accommodating all parameters including kV/MV imaging triggers in the plan can be locally loaded at this mode, however it is difficult and laborious to compose one in a text editor. In this study, a stand-along interactive XML beam composing application, TrueBeam TeachMod, was developed on Windows platforms to assist users in making their unique plans in a WYSWYG manner. A conventional plan can be imported in a DICOM RT object as the start of the beam editing process in which trajectories of all axes of a TrueBeam machine can be modified to the intended values at any control point. TeachMod also includes libraries of predefined imaging and treatment procedures to further expedite the process. Results: The TeachMod application is a major of the TeachMod module within DICOManTX. It fully supports TrueBeam 2.0. Trajectories of all axes including all MLC leaves can be graphically rendered and edited as needed. The time for XML beam composing has been reduced to a negligible amount regardless the complexity of the plan. A good understanding of XML language and TrueBeam schema is not required though preferred. Conclusion: Creating XML beams manually in a text editor will be a lengthy error-prone process for sophisticated plans. A XML beam composing tool is highly desirable for R and D activities. It will bridge the gap between scopes of TrueBeam capabilities and their clinical application potentials

  4. [True/Flex intramedullary nailing for forearm shaft fractures. Long-term results].

    Science.gov (United States)

    Trlica, J; Počepcov, I; Kočí, J; Frank, M; Holeček, T; Dědek, T

    2012-01-01

    Presentation of technical experience and the clinical and functional results of intramedullary fixation of forearm shaft fractures. Between January 1994 and December 2009, a total of 96 patients with 144 radial and/or ulnar fractures (ulna, 33; radius,15; both, 48) were treated by nailing (True/Flex®). According to the AO classification there were 22-A, 22-B and 22-C type fractures in 39 (41%), 44 (46%) and 13 (13%).cases, respectively. Of these, 82 (85%) were closed (types: 0, 48; I, 33; II, 1) and 14 (15%) were open (types: I, 13; II, 1; III, 0) fractures. Seventy-eight patients (81%) were followed up and their functional outcomes were evaluated according to the criteria of Anderson et al. The average interval between the operation and final follow-up was 28 months (15 to 96 months) The average time to surgery was 2.2 days (0 to 25 days). Early complications were recorded in 4% of the patients (1x bursitis olecrani; 1x end cup replacement; 1x bending of nails) and late complications in 15% (5x non-union; 2x delay union; 4x bursitis olecrani; 1x ruptured tendon). Bone healing was achieved in 95% of the cases and took on average 16 weeks (7 to 34 weeks). No infection, refracture or synostosis occurred. Primary loss of reduction was recorded in four cases due to distraction in one, bent nails in two and a wrong size of the implant in one; secondary loss of reduction was found in three cases, with two cases of radius shortening and one 10°malrotation. No primary malrotation was recorded, but secondary loss of alignment was seen in the distal part of the radius and the proximal part of the ulna. Functional results according to the Anderson criteria were excellent and good in 87% of the cases. Intramedullary mailing provides good stability to mid- and distal-third shaft fractures of the ulna and mid- and proximalthird shaft fractures of the radius, particularly in AO type A and type B fractures. The technical aspects of the method are analysed in detail in this paper

  5. SU-F-BRE-11: Neutron Measurements Around the Varian TrueBeam Linac

    Energy Technology Data Exchange (ETDEWEB)

    Maglieri, R; Seuntjens, J; Kildea, J [McGill University, Montreal, QC (Canada); Liang, L; DeBlois, F [Jewish General Hospital, Montreal, QC (Canada); Evans, M [Montreal General Hospital, Montreal, QC (Canada); Licea, A [Canadian Nuclear Safety Comission, Ottawa, Ontario (Canada); Dubeau, J; Witharana, S [Detec, Gatineau, QC (Canada)

    2014-06-15

    Purpose: With the emergence of flattening filter free (FFF) photon beams, several authors have noted many advantages to their use. One such advantage is the decrease in neutron production by photonuclear reactions in the linac head. In the present work we investigate the reduction in neutrons from a Varian TrueBeam linac using the Nested Neutron Spectrometer (NNS, Detec). The neutron spectrum, total fluence and source strength were measured and compared for 10 MV with and without flattening filter and the effect of moderation by the room and maze was studied for the 15 MV beam. Methods: The NNS, similar to traditional Bonner sphere detectors but operated in current mode, was used to measure the neutron fluence and spectrum. The NNS was validated for use in high dose rate environments using Monte Carlo simulations and calibrated at NIST and NRC Canada. Measurements were performed at several positions within the treatment room and maze with the linac jaws closed to maximize neutron production. Results: The measurements showed a total fluence reduction between 35-40% in the room and maze when the flattening filter was removed. The neutron source strength Qn was calculated from in-room fluence measurements and was found to be 0.042 × 10{sup 2} n/Gy, 0.026 × 10{sup 2} n/Gy and 0.59 × 101{sup 2} n/Gy for the 10 MV, the 10 MV FFF and 15 MV beams, respectively. We measured ambient equivalent doses of 11 mSv/hr, 7 mSv/hr and 218 mSv/hr for the 10 MV, 10 MV FFF and 15 MV by the head. Conclusion: Our measurements revealed a decrease in total fluence, neutron source strength and equivalent dose of approximately 35-40% across the treatment room for the FFF compared to FF modes. This demonstrates, as expected, that the flattening filter is a major component of the neutron production for the TrueBeam. The authors greatly acknowledge support form the Canadian Nuclear Commission and the Natural Sciences and Engineering Research Council of Canada through the CREATE program. Co

  6. Children's difficulty with true belief tasks: Competence deficit or performance problem?

    Science.gov (United States)

    Oktay-Gür, Nese; Rakoczy, Hannes

    2017-09-01

    According to the standard picture of explicit theory of mind (ToM) development, children begin to (explicitly) ascribe beliefs to others and themselves from around age 4. The empirical basis of this picture comes from numerous studies consistently showing that children master verbal false belief (FB) tasks from around age 4 while children much younger have no difficulty in mastering structurally analogous true belief (TB) tasks. The standard picture, though, has come under serious attack from recent studies using TB tasks with wider age ranges. These studies have found that, paradoxically, children begin to fail TB tasks once they master FB tasks. Such findings cast doubt on the standard picture and suggest, instead, that FB tasks may be solved by much simpler strategies than proper belief reasoning. In the present study, we tested for the development of FB and TB performance in comprehensive and systematic ways. In particular, we tested the competing predictions of competence accounts (according to which TB failure reflects lack of conceptual competence) versus performance limitation accounts (according to which the standard picture is true yet children from around age 4 fail TB tasks due to performance factors). Studies 1 and 2 showed that performance in a variety of novel TB tasks showed a clear U-shaped curve, with children until age 3 and from age 10 performing competently and children in between failing, with strong negative correlations between TB and FB. Crucially, these patterns were found for various kinds of TB tasks, including those for which existing competence limitation accounts would not even predict any difficulty. Study 3, therefore, directly tested performance limitation accounts in terms of pragmatic and related factors and found that these patterns (failure in TB and negative TB-FB correlations) disappear once the relevant performance factors have been removed from the TB tasks. Taken together, these findings suggest that previous TB findings

  7. True Polar Wander and the Origin of the Hawaiian-Emperor Bend: New Evidence

    Science.gov (United States)

    Woodworth, D.; Gordon, R. G.; Seidman, L.; Zheng, L.

    2017-12-01

    We present an updated apparent polar wander (APW) path for the Pacific plate constructed from paleomagnetic poles determined from the skewness of marine magnetic anomalies, from equatorial sediment facies, and from paleocolatitudes of vertical cores of igneous rock. While paleocolatitude data provide some constraints, their usefulness is limited because they only limit the pole position in one direction, and the uncertainty in that direction is large because of the challenges of averaging secular variation. In contrast, secular variation contributes negligibly to the poles from skewness data, which give compact confidence limits for a well-defined interval of time. We review, update, or present six useful poles available for chrons 12r, 20r, 25r, 26r, 27r-31, and 32, corresponding respectively to 32 Ma, 44 Ma, 58 Ma, 60 Ma, 65 Ma, and 72 Ma. Moreover, we incorporate spin axis locations inferred from equatorial sediment facies [Suárez and Molnar; 1980; Gordon and Cape, 1981; Parés and Moore, 2005] and estimate their 95% confidence limits. An APW path for Pacific hotspots can be obtained by moving each Pacific plate paleomagnetic pole with the Pacific plate relative to the hotspots to a reconstruction that corresponds to the age of the pole. This path has a stillstand from 44 Ma to 12 Ma at a location (P1) about 3° from the present spin axis and a second stillstand from 81 Ma to 58 Ma at a location (P2) about 11° from the present spin axis. We hypothesize that the shift from P2 to P1 records an episode of true polar wander sometime between 58 and 44 Ma and that the shift from P1 to the present spin axis records another episode of true polar that has occurred since 12 Ma and may continue today. We test these hypotheses by comparing the APW path of Pacific hotspots with the APW path of Indo-Atlantic hotspots and find them in agreement. Our results imply that global hotspots have moved in unison with respect to the spin axis and that the Hawaiian-Emperor Bend (HEB

  8. True Local Recurrences after Breast Conserving Surgery have Poor Prognosis in Patients with Early Breast Cancer

    Science.gov (United States)

    Sarsenov, Dauren; Ilgun, Serkan; Ordu, Cetin; Alco, Gul; Bozdogan, Atilla; Elbuken, Filiz; Nur Pilanci, Kezban; Agacayak, Filiz; Erdogan, Zeynep; Eralp, Yesim; Dincer, Maktav

    2016-01-01

    Background: This study was aimed at investigating clinical and histopathologic features of ipsilateral breast tumor recurrences (IBTR) and their effects on survival after breast conservation therapy. Methods: 1,400 patients who were treated between 1998 and 2007 and had breast-conserving surgery (BCS) for early breast cancer (cT1-2/N0-1/M0) were evaluated. Demographic and pathologic parameters, radiologic data, treatment, and follow-up related features of the patients were recorded. Results: 53 patients (3.8%) had IBTR after BCS within a median follow-up of 70 months. The mean age was 45.7 years (range, 27-87 years), and 22 patients (41.5%) were younger than 40 years. 33 patients (62.3%) had true recurrence (TR) and 20 were classified as new primary (NP). The median time to recurrence was shorter in TR group than in NP group (37.0 (6-216) and 47.5 (11-192) months respectively; p = 0.338). Progesterone receptor positivity was significantly higher in the NP group (p = 0.005). The overall 5-year survival rate in the NP group (95.0%) was significantly higher than that of the TR group (74.7%, p 20 mm), high grade tumor and triple-negative molecular phenotype along with developing TR negatively affected overall survival (hazard ratios were 4.2 (CI 0.98-22.76), 4.6 (CI 1.07-13.03), 4.0 (CI 0.68-46.10), 6.5 (CI 0.03-0.68), and 6.5 (CI 0.02- 0.80) respectively, p 2 cm), high grade, triple negative phenotype, and having true recurrence were identified as independent prognostic factors with a negative impact on overall survival in this dataset of patients with recurrent breast cancer. In conjunction with a more intensive follow-up program, the role of adjuvant therapy strategies should be explored further in young patients with large and high-risk tumors to reduce the risk of TR. PMID:27158571

  9. European and Developing Countries Clinical Trials Partnership (EDCTP): the path towards a true partnership.

    Science.gov (United States)

    Matee, Mecky I; Manyando, Christine; Ndumbe, Peter M; Corrah, Tumani; Jaoko, Walter G; Kitua, Andrew Y; Ambene, Herman Pa; Ndounga, Mathieu; Zijenah, Lynn; Ofori-Adjei, David; Agwale, Simon; Shongwe, Steven; Nyirenda, Thomas; Makanga, Michael

    2009-07-20

    European and Developing Countries Clinical Trials Partnership (EDCTP) was founded in 2003 by the European Parliament and Council. It is a partnership of 14 European Union (EU) member states, Norway, Switzerland, and Developing Countries, formed to fund acceleration of new clinical trial interventions to fight the human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS), malaria and tuberculosis (TB) in the sub-Saharan African region. EDCTP seeks to be synergistic with other funding bodies supporting research on these diseases. EDCTP promotes collaborative research supported by multiple funding agencies and harnesses networking expertise across different African and European countries. EDCTP is different from other similar initiatives. The organisation of EDCTP blends important aspects of partnership that includes ownership, sustainability and responds to demand-driven research. The Developing Countries Coordinating Committee (DCCC); a team of independent scientists and representatives of regional health bodies from sub-Saharan Africa provides advice to the partnership. Thus EDCTP reflects a true partnership and the active involvement and contribution of these African scientists ensures joint ownership of the EDCTP programme with European counterparts. The following have been the major achievements of the EDCTP initiative since its formation in 2003; i) increase in the number of participating African countries from two to 26 in 2008 ii) the cumulative amount of funds spent on EDCTP projects has reached 150 m euros, iii) the cumulative number of clinical trials approved has reached 40 and iv) there has been a significant increase number and diversity in capacity building activities. While we recognise that EDCTP faced enormous challenges in its first few years of existence, the strong involvement of African scientists and its new initiatives such as unconditional funding to regional networks of excellence in sub-Saharan Africa is envisaged to

  10. Extracting Buildings from True Color Stereo Aerial Images Using a Decision Making Strategy

    Directory of Open Access Journals (Sweden)

    Eufemia Tarantino

    2011-07-01

    Full Text Available The automatic extraction of buildings from true color stereo aerial imagery in a dense built-up area is the main focus of this paper. Our approach strategy aimed at reducing the complexity of the image content by means of a three-step procedure combining reliable geospatial image analysis techniques. Even if it is a rudimentary first step towards a more general approach, the method presented proved useful in urban sprawl studies for rapid map production in flat area by retrieving indispensable information on buildings from scanned historic aerial photography. After the preliminary creation of a photogrammetric model to manage Digital Surface Model and orthophotos, five intermediate mask-layers data (Elevation, Slope, Vegetation, Shadow, Canny, Shadow, Edges were processed through the combined use of remote sensing image processing and GIS software environments. Lastly, a rectangular building block model without roof structures (Level of Detail, LoD1 was automatically generated. System performance was evaluated with objective criteria, showing good results in a complex urban area featuring various types of building objects.

  11. Crossflex: Concept and early development of a true building integrated wind turbine

    Energy Technology Data Exchange (ETDEWEB)

    Sharpe, Tim [Mackintosh Environmental Architecture Research Unit (MEARU), Glasgow School of Art, Glasgow, G3 6RQ, Scotland (United Kingdom); Proven, Gordon [Proven Energy Ltd. Wardhead Park, Stewarton, Ayrshire, KA3 5LH, Scotland (United Kingdom)

    2010-12-15

    This paper describes the concept development and work to date, of an innovative 'true' building integrated wind turbine. The context for this is the role of small-scale renewable energy in addressing climate change. In the UK a number of small wind turbines have reached the market, however, in almost all cases, these are existing HAWT or VAWT tower mounted systems. Due to their inherent design qualities, and issues such as planning requirements, these have much reduced output due to their form and siting and are unable to take advantage of augmented airflow around buildings. The Crossflex proposal is a radical new development of a Darrieus turbine form. As well as having a technically innovative flexible blade system, it also utilises a lightweight cowling system that can provide both augmented airflow and improved visual integration into new and existing building forms. It is a modular form that can be sited on ridges and corners of buildings to provide useful levels of generation. (author)

  12. Crossflex: Concept and early development of a true building integrated wind turbine

    International Nuclear Information System (INIS)

    Sharpe, Tim; Proven, Gordon

    2010-01-01

    This paper describes the concept development and work to date, of an innovative 'true' building integrated wind turbine. The context for this is the role of small-scale renewable energy in addressing climate change. In the UK a number of small wind turbines have reached the market, however, in almost all cases, these are existing HAWT or VAWT tower mounted systems. Due to their inherent design qualities, and issues such as planning requirements, these have much reduced output due to their form and siting and are unable to take advantage of augmented airflow around buildings. The Crossflex proposal is a radical new development of a Darrieus turbine form. As well as having a technically innovative flexible blade system, it also utilises a lightweight cowling system that can provide both augmented airflow and improved visual integration into new and existing building forms. It is a modular form that can be sited on ridges and corners of buildings to provide useful levels of generation. (author)

  13. Bone induction by surface-double-modified true bone ceramics in vitro and in vivo

    International Nuclear Information System (INIS)

    Li, Jingfeng; Chen, Liaobin; Deng, Yu; Zheng, Qixin; Guo, Xiaodong; Zou, Zhenwei; Liu, Yudong; Lan, Shenghui

    2013-01-01

    True bone ceramic (TBC), obtained by twice sintering fresh bovine cancellous bone at high temperatures, is an osteoconductive and bioactive bone substitute material that exhibits excellent biocompatibility with hard tissue. The authors have previously synthesized a novel BMP-2-related peptide, P24, and found that it could enhance the osteoblastic differentiation of cells. The objective of the present study was to construct a double-modified TBC via mineralization into simulated body fluid and P24 incorporation for enhanced bone formation. In vitro experiments revealed that surface mineralization-modified (SMM) TBC scaffolds demonstrated efficiency for sustained release of P24. The P24/SMM-TBC composite exhibited increased osteogenic activity by cell adhesion rate determination, MTT assay, alkaline phosphatase staining, and calcium nodule staining with alizarin red compared with SMM-TBC and TBC. In vivo studies showed that the P24/SMM-TBC composite scaffold promoted significant bone defect repair, in marked contrast to stand-alone SMM-TBC and TBC, based on the results of radiographic evaluation and histological examination. These findings indicate that SMM-TBC is a good scaffold for the controlled release of P24 and that the P24/SMM-TBC composite could improve the adhesion, proliferation and differentiation of cells and repair bone defects. The double-modified P24/SMM-TBC composite biomaterial shows potential for clinical application in bone tissue engineering. (paper)

  14. An in vitro lung model to assess true shunt fraction by multiple inert gas elimination.

    Directory of Open Access Journals (Sweden)

    Balamurugan Varadarajan

    Full Text Available The Multiple Inert Gas Elimination Technique, based on Micropore Membrane Inlet Mass Spectrometry, (MMIMS-MIGET has been designed as a rapid and direct method to assess the full range of ventilation-to-perfusion (V/Q ratios. MMIMS-MIGET distributions have not been assessed in an experimental setup with predefined V/Q-distributions. We aimed (I to construct a novel in vitro lung model (IVLM for the simulation of predefined V/Q distributions with five gas exchange compartments and (II to correlate shunt fractions derived from MMIMS-MIGET with preset reference shunt values of the IVLM. Five hollow-fiber membrane oxygenators switched in parallel within a closed extracorporeal oxygenation circuit were ventilated with sweep gas (V and perfused with human red cell suspension or saline (Q. Inert gas solution was infused into the perfusion circuit of the gas exchange assembly. Sweep gas flow (V was kept constant and reference shunt fractions (IVLM-S were established by bypassing one or more oxygenators with perfusate flow (Q. The derived shunt fractions (MM-S were determined using MIGET by MMIMS from the retention data. Shunt derived by MMIMS-MIGET correlated well with preset reference shunt fractions. The in vitro lung model is a convenient system for the setup of predefined true shunt fractions in validation of MMIMS-MIGET.

  15. 44-h ambulatory blood pressure monitoring: revealing the true burden of hypertension in pediatric hemodialysis patients.

    Science.gov (United States)

    Haskin, Orly; Wong, Cynthia J; McCabe, Lonisa; Begin, Brandy; Sutherland, Scott M; Chaudhuri, Abanti

    2015-04-01

    The blood pressure (BP) burden is high in pediatric hemodialysis (HD) patients and adversely affects prognosis. The aim of this study was to examine whether 44-h ambulatory BP monitoring (ABPM) provides additional relevant BP data compared with 24-h ABPM. ABPM was initiated at the end of the mid-week dialysis run in 13 stable pediatric HD patients and continued until the next run for 44 h. Day 1 was defined as the initial 24-h ABPM and Day 2 as the time period after that until the next dialysis run. All patients had an echocardiogram to calculate the left ventricular mass index (LVMI). A higher percentage of patients were diagnosed with hypertension from the 44-h ABPM than from the 24-h ABPM. All BP indexes and loads (except nighttime diastolic load) were significantly higher on Day 2 than on Day 1. Patients with BP loads of ≥ 25 % on 44-h ABPM had significantly higher LVMI than those patients with normal BP loads. No such association was found with 24-h ABPM and LVMI. Higher interdialytic weight gain was associated with higher Day-2 nighttime systolic BP load. The 44-h ABPM provides more information than the 24-h ABPM in terms of diagnosing and assessing the true burden of hypertension in pediatric HD patients. Elevated BP loads from 44-h ABPM correlate with a higher LVMI on the echocardiogram.

  16. Is it true that ozone is always toxic? The end of a dogma

    International Nuclear Information System (INIS)

    Bocci, Velio

    2006-01-01

    There are a number of good experimental studies showing that exposure by inhalation to prolonged tropospheric ozone damages the respiratory system and extrapulmonary organs. The skin, if extensively exposed, may also contribute to the damage. The undoubtful strong reactivity of ozone has contributed to establish the dogma that ozone is always toxic and its medical application must be proscribed. Although it is less known, judiciously practiced ozonetherapy is becoming very useful either on its own or applied in combination with orthodox medicine in a broad range of pathologies. The opponents of ozonetherapy base their judgment on the ozone chemistry, and physicians, without any knowledge of the problem, are often skeptical. During the last 15 years, a clear understanding of the action of ozone in biology and medicine has been gained, allowing today to argue if it is true that ozone is always toxic. The fundamental points that are discussed in this paper are: the topography, anatomical and biochemical characteristics of the organs daily exposed to ozone versus the potent antioxidant capacity of blood exposed to a small and precisely calculated dose of ozone only for a few minutes. It is becoming clear how the respiratory system undergoing a chronic oxidative stress can release slowly, but steadily, a huge amount of toxic compounds able to enter the circulation and cause serious damage. The aim of this paper is to objectively evaluate this controversial issue

  17. Observation of the imbalance among insulin, true insulin and leptin in type 2 diabetes mellitus patients

    International Nuclear Information System (INIS)

    Wang Susu; Zhang Zhaofu; Peng Chaosheng; Cao Ruian; Ma Xiaobing; Zang Guiming; Xia Qing; Long Nanzhan; Zhang Baohe; Wang Hongying

    2005-01-01

    To observe the imbalance among immunoreactive insulin (IRI), true insulin (TI) and leptin (LEP) in type 2 diabetes mellitus (DM)patients, 39 subjects with type 2 DM patients and 31 normal control subjects were studied. IRI was measured with RIA, while TI and LEP were determined by BA-ELISA. In type 2 DM patients the IRI concentration (16.87±1.22 mIU/L) was higher than that of normal subjects(12.33±l.31 mIU/L), and the ratio of IRI/TI(11.10±1.98) was significantly increased, but the insulin sensitivity index was obviously reduced. There was good positive correlation between IRI, TI and LEP in control individuals(r value for IRI and TI was 0.553, for IRI and LEP was 0.631 and for LEP and TI was 0.483; P<0.001 for all), where as similar correlation was not observed in the cases of type 2 DM. The results suggest that there is a good modulation among IRI, TI and LEP in normal individuals, but there exist insulin resistance, relative lack of TI and imbalance of IRI-TI-LEP axis in type 2 DM patients. (authors)

  18. Brief, pre-learning stress reduces false memory production and enhances true memory selectively in females.

    Science.gov (United States)

    Zoladz, Phillip R; Peters, David M; Kalchik, Andrea E; Hoffman, Mackenzie M; Aufdenkampe, Rachael L; Woelke, Sarah A; Wolters, Nicholas E; Talbot, Jeffery N

    2014-04-10

    Some of the previous research on stress-memory interactions has suggested that stress increases the production of false memories. However, as accumulating work has shown that the effects of stress on learning and memory depend critically on the timing of the stressor, we hypothesized that brief stress administered immediately before learning would reduce, rather than increase, false memory production. In the present study, participants submerged their dominant hand in a bath of ice cold water (stress) or sat quietly (no stress) for 3 min. Then, participants completed a short-term memory task, the Deese-Roediger-McDermott paradigm, in which they were presented with 10 different lists of semantically related words (e.g., candy, sour, sugar) and, after each list, were tested for their memory of presented words (e.g., candy), non-presented unrelated "distractor" words (e.g., hat), and non-presented semantically related "critical lure" words (e.g., sweet). Stress, overall, significantly reduced the number of critical lures recalled (i.e., false memory) by participants. In addition, stress enhanced memory for the presented words (i.e., true memory) in female, but not male, participants. These findings reveal that stress does not unequivocally enhance false memory production and that the timing of the stressor is an important variable that could mediate such effects. Such results could have important implications for understanding the dependability of eyewitness accounts of events that are observed following stress. Copyright © 2014 Elsevier Inc. All rights reserved.

  19. Stress and emotional valence effects on children's versus adolescents' true and false memory.

    Science.gov (United States)

    Quas, Jodi A; Rush, Elizabeth B; Yim, Ilona S; Edelstein, Robin S; Otgaar, Henry; Smeets, Tom

    2016-01-01

    Despite considerable interest in understanding how stress influences memory accuracy and errors, particularly in children, methodological limitations have made it difficult to examine the effects of stress independent of the effects of the emotional valence of to-be-remembered information in developmental populations. In this study, we manipulated stress levels in 7-8- and 12-14-year-olds and then exposed them to negative, neutral, and positive word lists. Shortly afterward, we tested their recognition memory for the words and false memory for non-presented but related words. Adolescents in the high-stress condition were more accurate than those in the low-stress condition, while children's accuracy did not differ across stress conditions. Also, among adolescents, accuracy and errors were higher for the negative than positive words, while in children, word valence was unrelated to accuracy. Finally, increases in children's and adolescents' cortisol responses, especially in the high-stress condition, were related to greater accuracy but not false memories and only for positive emotional words. Findings suggest that stress at encoding, as well as the emotional content of to-be-remembered information, may influence memory in different ways across development, highlighting the need for greater complexity in existing models of true and false memory formation.

  20. True retention of nutrients on cooking of Australian retail lamb cuts of differing carcass classification characteristics.

    Science.gov (United States)

    Kosulwat, Somkiat; Greenfield, Heather; Buckle, Kenneth A

    2003-12-01

    The true retention of nutrients (proximate principles and cholesterol) on cooking of three retail cuts from lambs classified by weight, sex and fatness score was investigated. Fat retentions of the total cut and of the lean portion of lamb legs and mid-loin chops were not affected by carcass fatness, weight and sex or their interactions, however, the fat retention of the total cut and of the lean portion of forequarter chops was affected by fat score, with forequarter chops from fat score 1 retaining more fat than did chops of carcasses of higher fat score. Overall, fat was lost by all cuts (total cut) on cooking, with only 70-80% of fat being retained, but fat content of lean only increased on cooking (retention >100%), indicating the passage of fat into the lean portion from the external fat cover during the cooking process. Carcass factors and their interactions had little or no effect on the protein, water and ash retentions of the total cut or the lean portions of the three cuts. Cholesterol retention by the lean portion of three cooked lamb cuts was not affected by any carcass factors or their interactions. Cholesterol retentions were ∼99% for total cuts and tended to be ∼102% for the lean portions.

  1. Cosmological implications of the transition from the false vacuum to the true vacuum state

    Energy Technology Data Exchange (ETDEWEB)

    Stachowski, Aleksander [Jagiellonian University, Astronomical Observatory, Krakow (Poland); Szydlowski, Marek [Jagiellonian University, Astronomical Observatory, Krakow (Poland); Jagiellonian University, Mark Kac Complex Systems Research Centre, Krakow (Poland); Urbanowski, Krzysztof [University of Zielona Gora, Institute of Physics, Zielona Gora (Poland)

    2017-06-15

    We study cosmology with running dark energy. The energy density of dark energy is obtained from the quantum process of transition from the false vacuum state to the true vacuum state. We use the Breit-Wigner energy distribution function to model the quantum unstable systems and obtain the energy density of the dark energy parametrization ρ{sub de}(t). We also use Krauss and Dent's idea linking properties of the quantum mechanical decay of unstable states with the properties of the observed Universe. In the cosmological model with this parametrization there is an energy transfer between dark matter and dark energy. The intensity of this process, measured by a parameter α, distinguishes two scenarios. As the Universe starts from the false vacuum state, for the small value of α (0 < α < 0.4) it goes through an intermediate oscillatory (quantum) regime of the density of dark energy, while for α > 0.4 the density of the dark energy jumps down. In both cases the present value of the density of dark energy is reached. From a statistical analysis we find this model to be in good agreement with the astronomical data and practically indistinguishable from the ΛCDM model. (orig.)

  2. Effects of Some Additives on In Vitro True Digestibility of Wheat and Soybean Straw Pellets

    Directory of Open Access Journals (Sweden)

    Kılıc Unal

    2017-07-01

    Full Text Available This study was aimed to explore the nutrient content, relative feed values (RFV and in vitro true digestibilities (IVTD of wheat straw and soybean straw pellets produced with the addition of molasses, guar meal and sepiolite. In this experiment, 16 groups were created for 2 different straws (wheat/soybean straws, 2 different sepiolite applications (available/not available and 4 different applications (control, guar meal, molasses, guar meal+molasses in accordance with the 2×2×4 factorial design. A Daisy incubator was used to determine the IVTD of the feeds. According to the results, molasses and guar meal increased the RFV of soybean straws, while molasses and guar meal treatments and sepiolite did not affect the RFV of wheat straws. It was observed that sepiolite increased the RFV’s of soybean straw for guar meal and guar meal+molasses. The higher IVTD’s were found for guar meal (without sepiolite treatment of soybean straw and guar meal (with sepiolite treatment of wheat straw. Molasses and guar meal addition to wheat and soybean straws improved the crude protein contents. In conclusion, straw pelleting can be used as an alternative forage conservation method to close the gap in forage supply during the winter.

  3. Hyoscine versus diazepam for the management of true vertigo in the emergency department

    Directory of Open Access Journals (Sweden)

    Hamid Kariman

    2017-06-01

    Full Text Available The present study was a double-blind clinical trial to compare the efficiency of hysocine and diazepam in vertigo treatment. Eligible patients (n=69 were randomly divided into 2 groups of 5 mg hyoscine and 10 mg diazepam. Severity of vertigo was measured in supine and sitting position, and while turning the head. Vertigo severity was assessed before, and 1 and 2 hours after administration of the drug. Treatment success rate of diazepam in relieving vertigo in different positions varied between 88.9 and 100%, while this rate was 31.2–73.5% in hyoscine treatment group (p<0.01. Prescription of diazepam led to complete relief of vertigo in 40–63% of the patients, while this rate was only 2.6–12.5% in hyoscine treatment group (p<0.001. It is likely that diazepam is a better option than hyoscine for management of true vertigo in patients presenting to the emergency department.

  4. A True Delphi Approach: Developing a Tailored Curriculum in Response to Local Agriscience Need

    Energy Technology Data Exchange (ETDEWEB)

    Rubenstein, Eric; Thoron, Andrew; Burleson, Sarah

    2012-02-07

    The Delphi approach is a structured communication technique, developed as a systematic, interactive forecasting method which relies on a panel of experts. In this specific case experts from Industry, Education and Extension fields addressed needs for educational programs in a traditional agriculturally-based community, environmentally conscious practices in order to restore environmental integrity and multi-disciplinary approach to solve sustainability problems facing the agricultural industry. The experts were divided into two main groups, (A) Secondary and (B) Post-secondary, and answered questionnaires in three rounds: • 1st Round – Participants generated a list of knowledge, skills, and competencies followed • 2nd Round – Panelists rated each item • 3rd Round – Panelists were given the opportunity to combine and add additional items As a result, top six items from both groups were not found similar, secondary panelists centralized around employment skills and post-secondary panelists focused on content areas. Implications include a need for content-based curriculum for post-secondary graduates, utilization of true-Delphi technique for future curriculum development research and further examination of students that complete secondary and post-secondary programs in biofuels/sustainable agriculture.

  5. CFHT's SkyProbe: True Atmospheric Attenuation Measurement in the Telescope Field

    Science.gov (United States)

    Cuillandre, J.-C.; Magnier, E. A.; Isani, S.; Sabin, D.; Knight, W.; Kras, S.; Lai, K.

    Developed at the Canada France Hawaii Telescope (CFHT), SkyProbe is a system that allows the direct measurement of the true attenuation by clouds. This measurement is performed approximately once per min, directly on the field viewed by the telescope. It has been possible to make this system relatively inexpensively due to low cost CCD cameras available on the amateur market. A crucial addition to this hardware is the recent availability of a full-sky photometry catalog at the appropriate depth: the Tycho catalog from the Hipparcos mission. A very important element in the SkyProbe data set creation is the automatic data analysis pipeline, Elixir, developed at CFHT for the improved operation of the CFHT wide-field imagers CFH12K and MegaCam. SkyProbe's FITS images are processed in real time, and the pipeline output (a zero point attenuation) provides the current sky transmission to the observers and aids immediate decision making. These measurements are also attached to the archived data, adding a key tool for future use by other astronomers. Specific features of the detector, such as intra pixel quantum efficiency variations, must be taken into consideration since the data are strongly undersampled.

  6. Acute erythremic myelosis (true erythroleukaemia): a variant of AML FAB-M6.

    Science.gov (United States)

    Hasserjian, R P; Howard, J; Wood, A; Henry, K; Bain, B

    2001-03-01

    Classic erythroleukaemia (acute myeloid leukaemia M6, or M6 AML) is defined as an excess of myeloblasts in an erythroid predominant background. Leukaemia variants in which the primitive blast cells are demonstrably erythroid are extremely rare and poorly characterised. Variably referred to as "true erythroleukaemia" or "acute erythremic myelosis", they are often included within the M6 AML category even though they do not meet strict criteria for this type of AML. Two cases of acute erythroid neoplasia are presented with clinical, morphological, immunophenotypic, and cytogenetic analysis. Both patients presented with profound anaemia, one in a setting of long standing myelodysplasia. Bone marrow examination revealed a predominant population of highly dysplastic erythroid cells in both cases. In one case, the liver was infiltrated by neoplastic erythroid cells. Both patients died within four months of diagnosis. This report illustrates that cases of acute leukaemia occur in which the dominant neoplastic cell is a primitive erythroid cell without an accompanying increase in myeloblasts. This does not preclude the neoplastic clone originating in a multipotent haemopoietic stem cell, as suggested by cases arising in patients with myelodysplasia. Acute erythremic myelosis should be recognised as a distinct variant of M6 AML.

  7. Do Arthroscopic Fluid Pumps Display True Surgical Site Pressure During Hip Arthroscopy?

    Science.gov (United States)

    Ross, Jeremy A; Marland, Jennifer D; Payne, Brayden; Whiting, Daniel R; West, Hugh S

    2018-01-01

    To report on the accuracy of 5 commercially available arthroscopic fluid pumps to measure fluid pressure at the surgical site during hip arthroscopy. Patients undergoing hip arthroscopy for femoroacetabular impingement were block randomized to the use of 1 of 5 arthroscopic fluid pumps. A spinal needle inserted into the operative field was used to measure surgical site pressure. Displayed pump pressures and surgical site pressures were recorded at 30-second intervals for the duration of the case. Mean differences between displayed pump pressures and surgical site pressures were obtained for each pump group. Of the 5 pumps studied, 3 (Crossflow, 24K, and Continuous Wave III) reflected the operative field fluid pressure within 11 mm Hg of the pressure readout. In contrast, 2 of the 5 pumps (Double Pump RF and FMS/DUO+) showed a difference of greater than 59 mm Hg between the operative field fluid pressure and the pressure readout. Joint-calibrated pumps more closely reflect true surgical site pressure than gravity-equivalent pumps. With a basic understanding of pump design, either type of pump can be used safely and efficiently. The risk of unfamiliarity with these differences is, on one end, the possibility of pump underperformance and, on the other, potentially dangerously high operating pressures. Level II, prospective block-randomized study. Copyright © 2017. Published by Elsevier Inc.

  8. TRUE METABOLIZABLE ENERGY AND DIGESTIBILITY OF FIVE Vigna unguiculata VARIETIES IN CHICKENS

    Directory of Open Access Journals (Sweden)

    Luis Armando Sarmiento-Franco

    2010-11-01

    Full Text Available This study was carried out to evaluate the effect of heat-treatment on grain true metabolizable energy (TME, dry matter and gross energy digestibilities of five Vigna unguiculata varieties: H82, T782, TM97, C666 y XL. The grain of the former three varieties were heat-treated, and offered raw or cooked, whereas grain of the late two varieties were used only row, resulting in a total of eight treatments. The heat treatment consisted of watering the grains with boiling water for 30 minutes and drying at 60°C.  Forty-five Hubbard male chickens (2.1 ± 0.2 kg housed in individual wire pens were used to evaluate the treatments. Five chickens from each treatment were fed 40 g of treated grain in mash form, using the force-feeding technique. Additionally, five fasted chickens were used to calculate the endogenous energy and DM losses. The data were submitted to an analysis of variance according to the randomized statistical model; to evaluate the effect of heat treatment orthogonal contrasts were performed. There were no significant differences in all the variables neither among varieties nor between heat treatments (P>0.05. TME values in this study were similar to those found in the literature and equivalent to the TME value of soybean meal, a conventional feedstuff used in the poultry industry.

  9. Cosmological implications of the transition from the false vacuum to the true vacuum state

    International Nuclear Information System (INIS)

    Stachowski, Aleksander; Szydlowski, Marek; Urbanowski, Krzysztof

    2017-01-01

    We study cosmology with running dark energy. The energy density of dark energy is obtained from the quantum process of transition from the false vacuum state to the true vacuum state. We use the Breit-Wigner energy distribution function to model the quantum unstable systems and obtain the energy density of the dark energy parametrization ρ_d_e(t). We also use Krauss and Dent's idea linking properties of the quantum mechanical decay of unstable states with the properties of the observed Universe. In the cosmological model with this parametrization there is an energy transfer between dark matter and dark energy. The intensity of this process, measured by a parameter α, distinguishes two scenarios. As the Universe starts from the false vacuum state, for the small value of α (0 0.4 the density of the dark energy jumps down. In both cases the present value of the density of dark energy is reached. From a statistical analysis we find this model to be in good agreement with the astronomical data and practically indistinguishable from the ΛCDM model. (orig.)

  10. True and false recall and dissociation among maltreated children: the role of self-schema.

    Science.gov (United States)

    Valentino, Kristin; Cicchetti, Dante; Rogosch, Fred A; Toth, Sheree L

    2008-01-01

    The current investigation addresses the manner through which trauma affects basic memory and self-system processes. True and false recall for self-referent stimuli were assessed in conjunction with dissociative symptomatology among abused (N=76), neglected (N=92), and nonmaltreated (N=116) school-aged children. Abused, neglected, and nonmaltreated children did not differ in the level of processing self-schema effect or in the occurrence and frequency of false recall. Rather, differences in the affective valence of false recall emerged as a function of maltreatment subtype and age. Regarding dissociation, the abused children displayed higher levels of dissociative symptomatology than did the nonmaltreated children. Although abused, neglected, and nonmaltreated children did not exhibit differences in the valence of their self-schemas, positive and negative self-schemas were related to self-integration differently among the subgroups of maltreatment. Negative self-schemas were associated with increased dissociation among the abused children, whereas positive self-schemas were related to increased dissociation for the neglected children. Thus, positive self-schemas displayed by the younger neglected children were related to higher dissociation, suggestive of defensive self-processing. Implications for clinical intervention are underscored.

  11. Microcomb-Based True-Time-Delay Network for Microwave Beamforming With Arbitrary Beam Pattern Control

    Science.gov (United States)

    Xue, Xiaoxiao; Xuan, Yi; Bao, Chengying; Li, Shangyuan; Zheng, Xiaoping; Zhou, Bingkun; Qi, Minghao; Weiner, Andrew M.

    2018-06-01

    Microwave phased array antennas (PAAs) are very attractive to defense applications and high-speed wireless communications for their abilities of fast beam scanning and complex beam pattern control. However, traditional PAAs based on phase shifters suffer from the beam-squint problem and have limited bandwidths. True-time-delay (TTD) beamforming based on low-loss photonic delay lines can solve this problem. But it is still quite challenging to build large-scale photonic TTD beamformers due to their high hardware complexity. In this paper, we demonstrate a photonic TTD beamforming network based on a miniature microresonator frequency comb (microcomb) source and dispersive time delay. A method incorporating optical phase modulation and programmable spectral shaping is proposed for positive and negative apodization weighting to achieve arbitrary microwave beam pattern control. The experimentally demonstrated TTD beamforming network can support a PAA with 21 elements. The microwave frequency range is $\\mathbf{8\\sim20\\ {GHz}}$, and the beam scanning range is $\\mathbf{\\pm 60.2^\\circ}$. Detailed measurements of the microwave amplitudes and phases are performed. The beamforming performances of Gaussian, rectangular beams and beam notch steering are evaluated through simulations by assuming a uniform radiating antenna array. The scheme can potentially support larger PAAs with hundreds of elements by increasing the number of comb lines with broadband microcomb generation.

  12. Novel true-motion estimation algorithm and its application to motion-compensated temporal frame interpolation.

    Science.gov (United States)

    Dikbas, Salih; Altunbasak, Yucel

    2013-08-01

    In this paper, a new low-complexity true-motion estimation (TME) algorithm is proposed for video processing applications, such as motion-compensated temporal frame interpolation (MCTFI) or motion-compensated frame rate up-conversion (MCFRUC). Regular motion estimation, which is often used in video coding, aims to find the motion vectors (MVs) to reduce the temporal redundancy, whereas TME aims to track the projected object motion as closely as possible. TME is obtained by imposing implicit and/or explicit smoothness constraints on the block-matching algorithm. To produce better quality-interpolated frames, the dense motion field at interpolation time is obtained for both forward and backward MVs; then, bidirectional motion compensation using forward and backward MVs is applied by mixing both elegantly. Finally, the performance of the proposed algorithm for MCTFI is demonstrated against recently proposed methods and smoothness constraint optical flow employed by a professional video production suite. Experimental results show that the quality of the interpolated frames using the proposed method is better when compared with the MCFRUC techniques.

  13. Real-time interpolation for true 3-dimensional ultrasound image volumes.

    Science.gov (United States)

    Ji, Songbai; Roberts, David W; Hartov, Alex; Paulsen, Keith D

    2011-02-01

    We compared trilinear interpolation to voxel nearest neighbor and distance-weighted algorithms for fast and accurate processing of true 3-dimensional ultrasound (3DUS) image volumes. In this study, the computational efficiency and interpolation accuracy of the 3 methods were compared on the basis of a simulated 3DUS image volume, 34 clinical 3DUS image volumes from 5 patients, and 2 experimental phantom image volumes. We show that trilinear interpolation improves interpolation accuracy over both the voxel nearest neighbor and distance-weighted algorithms yet achieves real-time computational performance that is comparable to the voxel nearest neighbor algrorithm (1-2 orders of magnitude faster than the distance-weighted algorithm) as well as the fastest pixel-based algorithms for processing tracked 2-dimensional ultrasound images (0.035 seconds per 2-dimesional cross-sectional image [76,800 pixels interpolated, or 0.46 ms/1000 pixels] and 1.05 seconds per full volume with a 1-mm(3) voxel size [4.6 million voxels interpolated, or 0.23 ms/1000 voxels]). On the basis of these results, trilinear interpolation is recommended as a fast and accurate interpolation method for rectilinear sampling of 3DUS image acquisitions, which is required to facilitate subsequent processing and display during operating room procedures such as image-guided neurosurgery.

  14. A case of successfully cured carcinoma of the true vocal folds in the larynx

    International Nuclear Information System (INIS)

    Shivarov, G.; Tomov, D.

    2017-01-01

    Objective and subject of the study: Laryngeal carcinoma is a socially significant malignancy in our country as well. Between 1981 and 2010, standardized morbidity (global standard) of 100,000 in Bulgaria increased in men from 6.4 to 9.1, and in women - from 0.3 to 0.7. Recently, a number of reports were published, showing that timely individualized treatment leads to definitive curing of patients with this disease. Methods used: A 37 years old man was hospitalized with a complaint of dysphonia persisting despite conservative treatment for two months. Results: Objectively thickened vocal folds were observed. In this case, the left one was uneven, bruised and with unrestricted mobility. The histological examination of the biopsy material shows moderately differentiated spinocellular carcinoma in the left and squamous papilloma T1 No Mx - in the right fold. A planned hemylarringectomy was performed. Intraoperatively, a susceptible stretch in the right vocal fold was detected, proved in two weeks to be squamous cell carcinoma. A lower tracheotomy was performed, followed by telangatherapy alone. The four-year follow-up indicates a favorable course of the disease and a lack of relapse. Conclusion: The combination of surgical intervention with telegamma therapy in cases of isolated carcinoma of the true vocal folds in the larynx can be applied to strictly selected patients in order to achieve optimal therapeutic outcomes. [bg

  15. Diagnosing true virtue? Remote scenarios, warranted virtue attributions, and virtuous medical practice.

    Science.gov (United States)

    Oakley, Justin

    2016-02-01

    Immanuel Kant argues in the Foundations that remote scenarios are diagnostic of genuine virtue. When agents commonly thought to have a particular virtue fail to exhibit that virtue in an extreme situation, he argues, they do not truly have the virtue at all, and our propensities to fail in such ways indicate that true virtue might never have existed. Kant's suggestion that failure to show, say, courage in extraordinary circumstances necessarily silences one's claim to have genuine courage seems to rely on an implausibly demanding standard for warranted virtue attributions. In contrast to this approach, some philosophers-such as Robert Adams and John Doris-have argued for probabilistic accounts of warranted virtue attributions. But despite the initial plausibility of such accounts, I argue that a sole reliance on probabilistic approaches is inadequate, as they are insufficiently sensitive to considerations of credit and fault, which emerge when agents have developed various insurance strategies and protective capacities against their responding poorly to particular eventualities. I also argue that medical graduates should develop the sorts of virtuous dispositions necessary to protect patient welfare against various countervailing influences (even where such influences might be encountered only rarely), and that repeated failures to uphold the proper goals of medicine in emergency scenarios might indeed be diagnostic of whether an individual practitioner does have the relevant medical virtue. In closing, I consider the dispositions involved in friendship. I seek to develop a principled way of determining when remote scenarios can be illuminating of genuine friendship and genuine virtue.

  16. True-slime-mould-inspired hydrostatically coupled oscillator system exhibiting versatile behaviours

    International Nuclear Information System (INIS)

    Umedachi, Takuya; Ito, Kentaro; Idei, Ryo; Ishiguro, Akio

    2013-01-01

    Behavioural diversity is an indispensable attribute of living systems, which makes them intrinsically adaptive and responsive to the demands of a dynamically changing environment. In contrast, conventional engineering approaches struggle to suppress behavioural diversity in artificial systems to reach optimal performance in given environments for desired tasks. The goals of this research include understanding the essential mechanism that endows living systems with behavioural diversity and implementing the mechanism in robots to exhibit adaptive behaviours. For this purpose, we have focused on an amoeba-like unicellular organism: the plasmodium of true slime mould. Despite the absence of a central nervous system, the plasmodium exhibits versatile spatiotemporal oscillatory patterns and switches spontaneously among these patterns. By exploiting this behavioural diversity, it is able to exhibit adaptive behaviour according to the situation encountered. Inspired by this organism, we built a real physical robot using hydrostatically coupled oscillators that produce versatile oscillatory patterns and spontaneous transitions among the patterns. The experimental results show that exploiting physical hydrostatic interplay—the physical dynamics of the robot—allows simple phase oscillators to promote versatile behaviours. The results can contribute to an understanding of how a living system generates versatile and adaptive behaviours with physical interplays among body parts. (paper)

  17. Activity of some aminoglycoside antibiotics against true fungi, Phytophthora and Pythium species.

    Science.gov (United States)

    Lee, H B; Kim, Y; Kim, J C; Choi, G J; Park, S-H; Kim, C-J; Jung, H S

    2005-01-01

    To investigate the in vitro antifungal and antioomycete activities of some aminoglycosides against true fungi and Phytophthora and Pythium species and to evaluate the potential of the antibiotics against Phytophthora late blight on plants. Antifungal and antioomycete activities of aminoglycoside antibiotics (neomycin, paromomycin, ribostamycin and streptomycin) and a paromomycin-producing strain (Streptomyces sp. AMG-P1) against Phytophthora and Pythium species and 10 common fungi were measured in potato dextrose broth (PDB) and on seedlings in pots. Paromomycin was the most active against Phytophthora and Pythium species with a minimal inhibitory concentration of 1-10 microg ml(-1) in PDB, but displayed low to moderate activities towards other common fungi at the same concentration. Paromomycin also showed potent in vivo activity against red pepper and tomato late blight diseases with 80 and 99% control value, respectively, at 100 microg ml(-1). In addition, culture broth of Streptomyces sp. AMG-P1 as a paromomycin producer exhibited high in vivo activity against late blight at 500 microg freeze-dried weight per millilitre. Among tested aminoglycoside antibiotics, paromomycin was the most active against oomycetes both in vitro and in vivo. Data from this study show that aminoglycoside antibiotics have in vitro and in vivo activities against oomycetes, suggesting that Streptomyces sp. AMG-P1 may be used as a biocontrol agent against oomycete diseases.

  18. Catastrophic regime shifts in model ecological communities are true phase transitions

    International Nuclear Information System (INIS)

    Capitán, J A; Cuesta, J A

    2010-01-01

    Ecosystems often undergo abrupt regime shifts in response to gradual external changes. These shifts are theoretically understood as a regime switch between alternative stable states of the ecosystem dynamical response to smooth changes in external conditions. Usual models introduce nonlinearities in the macroscopic dynamics of the ecosystem that lead to different stable attractors among which the shift takes place. Here we propose an alternative explanation of catastrophic regime shifts based on a recent model that pictures ecological communities as systems in continuous fluctuation, according to certain transition probabilities, between different micro-states in the phase space of viable communities. We introduce a spontaneous extinction rate that accounts for gradual changes in external conditions, and upon variations on this control parameter the system undergoes a regime shift with similar features to those previously reported. Under our microscopic viewpoint we recover the main results obtained in previous theoretical and empirical work (anomalous variance, hysteresis cycles, trophic cascades). The model predicts a gradual loss of species in trophic levels from bottom to top near the transition. But more importantly, the spectral analysis of the transition probability matrix allows us to rigorously establish that we are observing the fingerprints, in a finite size system, of a true phase transition driven by background extinctions

  19. Existential crises in two religious patients: Vicissitudes of faith and the emergence of the true self.

    Science.gov (United States)

    Fattori, Lucia; Secchi, Cesare

    2015-08-01

    The authors present two clinical cases involving an existential crisis which led the patients to lose what had been the foundation in their lives, their faith. Although the therapeutic settings differ--the first patient had a few psychotherapy sessions following a psychotic episode with a mystical background, while the second was in the final stage of analytic treatment - the authors highlight how in both clinical cases a loss of faith becomes a total and urgent crisis of the Self. The fracture which ensues seems to generate an intense engagement of the body which, paradoxically during a loss of faith, induces an experience of ecstasy of the kind that has traditionally been reported. In the first case the experience of ecstasy was lived first-hand by the patient who thereafter redefined the psychotic breakdown as a "moment of truth"; whereas the second patient, through a deep projective identification, induces an eerie countertransferential feeling of 'metaphysical' shortfall in the agnostic psychoanalyst, triggering bewilderment, physical discomfort and awe in him. In both cases the authors believe that the notable somatic involvement may be correlated to a potentially profound and unprecedented contact with the True Self. Copyright © 2015 Institute of Psychoanalysis.

  20. Thrombotic thrombocytopenic purpura (TTP or Moschowitz syndrome: a true hematologic emergency

    Directory of Open Access Journals (Sweden)

    Deborah Melis

    2012-01-01

    Full Text Available Introduction: Thrombotic thrombocytopenic purpura (TTP is a thrombotic microangiopathy caused by congenital or inherited disorders involving the processing of the ultra-large forms of von Willebrand factor. As a result, platelet-rich microthrombi form in the small arterial vessels of various organs, particularly those of the brain, heart, and kidneys. The idiopathic autoimmune form of TTP is the most common. There are various subgroups of acquired TTP associated with HIV infection, sepsis, pregnancy, autoimmune disease, various disseminated malignancies, and drugs. If not promptly treated, TTP is associated with high mortality, making it a true medical emergency. Materials and methods: The article is based on a review of the literature published between January and October of 2009. Its aim is to clarify the diagnosis, treatment, and follow-up of TTP. Results: Diagnostic criteria include the presence of microangiopathic hemolytic anemia associated with thrombocytopenia in the absence of other obvious causes. Assays of ADAMTS13 activity and titration of acquired antibodies against this enzyme are indicated in the follow-up of disease and as prognostic indicators. Treatment centers around daily plasma exchange associated with immunosuppressant drug therapy, particularly steroids and more recently the monoclonal anti-CD20 antibody rituximab. Discussion: Despite improved treatment, TTP is still associated with significant mortality (10—20%, particularly when plasma exchange is initiated late. Relapse also occurs in a substantial proportion of patients (10—40% although the frequency of this outcome may be reduced by rituximab therapy.

  1. Evaluation of TRUE-1 tests with sorbing tracers using CHAN3D

    International Nuclear Information System (INIS)

    Moreno, L.

    2001-01-01

    Three tracer tests (STT1a, STT1b and STT2) with sorbing species performed as a part of the TRUE-1 experiments are studied. The tests were carried out in a radially converging flow geometry with a travel distance of about 5 m The injected sorbing tracers were: Na + , Sr 2+ , Ca 2+ , Ba 2+ , Cs + , Co 2+ , Rb + . The sorption properties of the tracer cover a wide interval. The tracer tests were modelled using the Channel Network Model, which assumes that fluid flow and solute transport take place through a network of channels. It includes solute transport by advection, diffusion into the rock matrix, and sorption within the matrix and onto the channel surface. Sorption and diffusion data were obtained from laboratory measurements carried out over generic Aespoe material. Some measurements were made using material from the Feature A. Large differences are found between the experimental and the predicted breakthrough curves. The predicted times are much shorter than the experimental ones. An attempt is made to explain these differences using various possible retardation mechanisms. Finally, it is concluded that several mechanisms must act simultaneously in order to explain the large differences

  2. Airway inflammation in chronic obstructive pulmonary disease (COPD): a true paradox.

    Science.gov (United States)

    Eapen, Mathew Suji; Myers, Stephen; Walters, Eugene Haydn; Sohal, Sukhwinder Singh

    2017-10-01

    Chronic obstructive pulmonary disease (COPD) is primarily an airway condition, which mainly affects cigarette smokers and presents with shortness of breath that is progressive and poorly reversible. In COPD research, there has been a long held belief that airway disease progression is due to inflammation. Although this may be true in the airway lumen with innate immunity activated by the effect of smoke or secondary to infection, the accurate picture of inflammatory cells in the airway wall, where the pathophysiological COPD remodeling occurs, is uncertain and debatable. Areas covered: The current review provides a comprehensive literature survey of the changes in the main inflammatory cells in human COPD patients and focuses on contrarian views that affect the prevailing dogma on inflammation. The review also delves into the role of oxidative stress and inflammasomes in modulating the immune response in COPD. Further, the effects of inflammation in affecting the epithelium, fibroblasts, and airway remodeling are discussed. Expert commentary: Inflammation as a driving force for airway wall damage and remodelling in early COPD is at the very least 'oversimplified' and is likely to be misleading. This has serious implications for rational thinking about the illness, including pathogenesis and designing therapy.

  3. Perception of self-tilt in a true and illusory vertical plane

    Science.gov (United States)

    Groen, Eric L.; Jenkin, Heather L.; Howard, Ian P.; Oman, C. M. (Principal Investigator)

    2002-01-01

    A tilted furnished room can induce strong visual reorientation illusions in stationary subjects. Supine subjects may perceive themselves upright when the room is tilted 90 degrees so that the visual polarity axis is kept aligned with the subject. This 'upright illusion' was used to induce roll tilt in a truly horizontal, but perceptually vertical, plane. A semistatic tilt profile was applied, in which the tilt angle gradually changed from 0 degrees to 90 degrees, and vice versa. This method produced larger illusory self-tilt than usually found with static tilt of a visual scene. Ten subjects indicated self-tilt by setting a tactile rod to perceived vertical. Six of them experienced the upright illusion and indicated illusory self-tilt with an average gain of about 0.5. This value is smaller than with true self-tilt (0.8), but comparable to the gain of visually induced self-tilt in erect subjects. Apparently, the contribution of nonvisual cues to gravity was independent of the subject's orientation to gravity itself. It therefore seems that the gain of visually induced self-tilt is smaller because of lacking, rather than conflicting, nonvisual cues. A vector analysis is used to discuss the results in terms of relative sensory weightings.

  4. Calculation of benefit reserves based on true m-thly benefit premiums

    Science.gov (United States)

    Riaman; Susanti, Dwi; Supriatna, Agus; Nurani Ruchjana, Budi

    2017-10-01

    Life insurance is a form of insurance that provides risk mitigation in life or death of a human. One of its advantages is measured life insurance. Insurance companies ought to give a sum of money as reserves to the customers. The benefit reserves are an alternative calculation which involves net and cost premiums. An insured may pay a series of benefit premiums to an insurer equivalent, at the date of policy issue, to the sum of to be paid on the death of the insured, or on survival of the insured to the maturity date. A balancing item is required and this item is a liability for one of the parties and the other is an asset. The balancing item, in loan, is the outstanding principle, an asset for the lender and the liability for the borrower. In this paper we examined the benefit reserves formulas corresponding to the formulas for true m-thly benefit premiums by the prospective method. This method specifies that, the reserves at the end of the first year are zero. Several principles can be used for the determined of benefit premiums, an equivalence relation is established in our discussion.

  5. True-3D accentuating of grids and streets in urban topographic maps enhances human object location memory.

    Directory of Open Access Journals (Sweden)

    Dennis Edler

    Full Text Available Cognitive representations of learned map information are subject to systematic distortion errors. Map elements that divide a map surface into regions, such as content-related linear symbols (e.g. streets, rivers, railway systems or additional artificial layers (coordinate grids, provide an orientation pattern that can help users to reduce distortions in their mental representations. In recent years, the television industry has started to establish True-3D (autostereoscopic displays as mass media. These modern displays make it possible to watch dynamic and static images including depth illusions without additional devices, such as 3D glasses. In these images, visual details can be distributed over different positions along the depth axis. Some empirical studies of vision research provided first evidence that 3D stereoscopic content attracts higher attention and is processed faster. So far, the impact of True-3D accentuating has not yet been explored concerning spatial memory tasks and cartography. This paper reports the results of two empirical studies that focus on investigations whether True-3D accentuating of artificial, regular overlaying line features (i.e. grids and content-related, irregular line features (i.e. highways and main streets in official urban topographic maps (scale 1/10,000 further improves human object location memory performance. The memory performance is measured as both the percentage of correctly recalled object locations (hit rate and the mean distances of correctly recalled objects (spatial accuracy. It is shown that the True-3D accentuating of grids (depth offset: 5 cm significantly enhances the spatial accuracy of recalled map object locations, whereas the True-3D emphasis of streets significantly improves the hit rate of recalled map object locations. These results show the potential of True-3D displays for an improvement of the cognitive representation of learned cartographic information.

  6. Linguistic and Cross-Cultural Complexities of A Specialized Legal Item: The ‘True And Fair’ Case

    Directory of Open Access Journals (Sweden)

    Annalisa Zanola

    2014-01-01

    The aim of our contribution is that of analysing the possible linguistic and cross-cultural contexts where the hendiadys true and fair was born, and exploring the meaning implications of the same ‘formula’ during the centuries. We start from the hypothesis that true and fair is a hendiadys, to show that the two terms take strength and completeness one from the other, so as to generate an only complex meaning, whose original usage was, last but not least,  a literary and poetical one. The analysis of the hendiadys moves from the non-legal to the legal context, following steps of the etymological and lexical research methodology.

  7. Calculating the true level of predictors significance when carrying out the procedure of regression equation specification

    Directory of Open Access Journals (Sweden)

    Nikita A. Moiseev

    2017-01-01

    Full Text Available The paper is devoted to a new randomization method that yields unbiased adjustments of p-values for linear regression models predictors by incorporating the number of potential explanatory variables, their variance-covariance matrix and its uncertainty, based on the number of observations. This adjustment helps to control type I errors in scientific studies, significantly decreasing the number of publications that report false relations to be authentic ones. Comparative analysis with such existing methods as Bonferroni correction and Shehata and White adjustments explicitly shows their imperfections, especially in case when the number of observations and the number of potential explanatory variables are approximately equal. Also during the comparative analysis it was shown that when the variance-covariance matrix of a set of potential predictors is diagonal, i.e. the data are independent, the proposed simple correction is the best and easiest way to implement the method to obtain unbiased corrections of traditional p-values. However, in the case of the presence of strongly correlated data, a simple correction overestimates the true pvalues, which can lead to type II errors. It was also found that the corrected p-values depend on the number of observations, the number of potential explanatory variables and the sample variance-covariance matrix. For example, if there are only two potential explanatory variables competing for one position in the regression model, then if they are weakly correlated, the corrected p-value will be lower than when the number of observations is smaller and vice versa; if the data are highly correlated, the case with a larger number of observations will show a lower corrected p-value. With increasing correlation, all corrections, regardless of the number of observations, tend to the original p-value. This phenomenon is easy to explain: as correlation coefficient tends to one, two variables almost linearly depend on each

  8. Been there before? Examining "familiarity" as a moderator for discriminating between true and false intentions.

    Science.gov (United States)

    Knieps, Melanie; Granhag, Pär A; Vrij, Aldert

    2014-01-01

    Prospection is thinking about possible future states of the world. Commitment to perform a future action-commonly referred to as intention-is a specific type of prospection. This knowledge is relevant when trying to assess whether a stated intention is a lie or the truth. An important observation is that thinking of, and committing to, future actions often evoke vivid and detailed mental images. One factor that affects how specific a person experiences these simulations is location-familiarity. The purpose of this study was to examine to what extent location-familiarity moderates how liars and truth tellers describe a mental image in an investigative interview. Liars were instructed to plan a criminal act and truth tellers were instructed to plan a non-criminal act. Before they could carry out these acts, the participants were intercepted and interviewed about the mental images they may have had experienced in this planning phase. Truth tellers told the truth whereas liars used a cover story to mask their criminal intentions. As predicted, the results showed that the truth tellers reported a mental image significantly more often than the liars. If a mental image was reported, the content of the descriptions did not differ between liars and truth tellers. In a post interview questionnaire, the participants rated the vividness (i.e., content and clarity) of their mental images. The ratings revealed that the truth tellers had experienced their mental images more vividly during the planning phase than the liars. In conclusion, this study indicates that both prototypical and specific representations play a role in prospection. Although location-familiarity did not moderate how liars and truth tellers describe their mental images of the future, this study allows some interesting insights into human future thinking. How these findings can be helpful for distinguishing between true and false intentions will be discussed.

  9. Towards true 3D textural analysis; using your crystal mush wisely.

    Science.gov (United States)

    Jerram, D. A.; Morgan, D. J.; Pankhurst, M. J.

    2014-12-01

    , including texture movie animations, are used from both plutonic and volcanic systems to highlight the roll of this approach towards a goal of true 3D textural analysis.

  10. Asymmetric rapid maxillary expansion in true unilateral crossbite malocclusion: a prospective controlled clinical study.

    Science.gov (United States)

    Ileri, Zehra; Basciftci, Faruk Ayhan

    2015-03-01

    To investigate the short-term effects of the asymmetric rapid maxillary (ARME) appliance on the vertical, sagittal, and transverse planes in patients with true unilateral posterior crossbite. Subjects were divided into two groups. The treatment group was comprised of 21 patients with unilateral posterior crossbite (mean age  =  13.3 ± 2.1 years). Members of this group were treated with the ARME appliance. The control group was comprised of 17 patients with Angle Class I who were kept under observation (mean age  =  12.3 ± 0.8 years). Lateral and frontal cephalograms were taken before the expansion (T1), immediately after expansion (T2), and at postexpansion retention (T3) in the treatment group and at preobservation (T1) and postobservation (T2) in the control group. A total of 34 measurements were assessed on cephalograms. For statistical analysis, the Wilcoxon test and analysis of covariance were used. The ARME appliance produced significant increases in nasal, maxillary base, upper arch, and lower arch dimensions (P ARME appliance created asymmetric increments in the transversal dimensions of the nose, maxilla, and upper arch in the short term. Asymmetric expansion therapy for subjects with unilateral maxillary deficiency may provide satisfactory outcomes in adolescents, with the exception of mandibular arch expansion. The triangular pattern of expansion caused clockwise rotation of the mandible and the occlusal plane and produced significant alterations in the vertical facial dimensions, whereas it created no displacement in maxilla in the sagittal plane.

  11. Capturing the True Value of Assistive Technologies to Consumers in Routine Outcome Measurement

    Directory of Open Access Journals (Sweden)

    Desleigh de Jonge

    2016-10-01

    Full Text Available (1 Background: Recent reforms in Australia, providing people with disability and older people with choice and control over allocated funding, have altered consumer expectations and transformed the landscape of assistive technology (AT service provision. The purpose of this study is to report on the routine AT outcomes of people who accessed an AT consultation service and examine how well these capture the impact of AT on their lives; (2 Methods: This study, which uses mixed methods for concurrent triangulation of the data, reports on the outcomes for 127 people who acquired a range of assistive technology in 2015 and examines the adequacy of an existing service outcome framework in capturing the true value of these technologies to AT users. Outcome data was routinely collected by a community service 2–4 months following an AT consultation. A telephone or face-to-face interview gathered demographic information as well as AT outcomes, using two standardized tools, the Individualized Prioritised Problem Assessment (IPPA and the EATS 6D. Qualitative comments relating to the impact of the AT on the person’s life were also documented; (3 Results: The acquired AT generally met or exceeded expectations of the person using the AT and the attending health professional. Overall, people experienced decreased difficulty and increased feelings of autonomy, with most of the reported improvements identified in mobility and usual activities; (4 Conclusion: Routine outcome data provide some evidence of the value of AT in addressing concerns as identified by clients. Qualitative data, which captured the impact of AT on people’s lives, suggest that the empowering and transformative aspects of AT are not currently being captured by existing measures.

  12. Neural correlates of true and false memory in mild cognitive impairment.

    Science.gov (United States)

    Sweeney-Reed, Catherine M; Riddell, Patricia M; Ellis, Judi A; Freeman, Jayne E; Nasuto, Slawomir J

    2012-01-01

    The goal of this research was to investigate the changes in neural processing in mild cognitive impairment. We measured phase synchrony, amplitudes, and event-related potentials in veridical and false memory to determine whether these differed in participants with mild cognitive impairment compared with typical, age-matched controls. Empirical mode decomposition phase locking analysis was used to assess synchrony, which is the first time this analysis technique has been applied in a complex cognitive task such as memory processing. The technique allowed assessment of changes in frontal and parietal cortex connectivity over time during a memory task, without a priori selection of frequency ranges, which has been shown previously to influence synchrony detection. Phase synchrony differed significantly in its timing and degree between participant groups in the theta and alpha frequency ranges. Timing differences suggested greater dependence on gist memory in the presence of mild cognitive impairment. The group with mild cognitive impairment had significantly more frontal theta phase locking than the controls in the absence of a significant behavioural difference in the task, providing new evidence for compensatory processing in the former group. Both groups showed greater frontal phase locking during false than true memory, suggesting increased searching when no actual memory trace was found. Significant inter-group differences in frontal alpha phase locking provided support for a role for lower and upper alpha oscillations in memory processing. Finally, fronto-parietal interaction was significantly reduced in the group with mild cognitive impairment, supporting the notion that mild cognitive impairment could represent an early stage in Alzheimer's disease, which has been described as a 'disconnection syndrome'.

  13. Anomalous Late Jurassic motion of the Pacific Plate with implications for true polar wander

    Science.gov (United States)

    Fu, Roger R.; Kent, Dennis V.

    2018-05-01

    True polar wander, or TPW, is the rotation of the entire mantle-crust system about an equatorial axis that results in a coherent velocity contribution for all lithospheric plates. One of the most recent candidate TPW events consists of a ∼30° rotation during Late Jurassic time (160-145 Ma). However, existing paleomagnetic documentation of this event derives exclusively from continents, which compose less than 50% of the Earth's surface area and may not reflect motion of the entire mantle-crust system. Additional paleopositional information from the Pacific Basin would significantly enhance coverage of the Earth's surface and allow more rigorous testing for the occurrence of TPW. We perform paleomagnetic analyses on core samples from Ocean Drilling Program (ODP) Site 801B, which were taken from the oldest available Pacific crust, to determine its paleolatitude during the Late Jurassic and Early Cretaceous (167-133 Ma). We find that the Pacific Plate underwent a steady southward drift of 0.49°-0.74° My-1 except for an interval between Kimmeridgian and Tithonian time (157-147 Ma), during which it underwent northward motion at 1.45° ± 0.76° My-1 (1σ). This trajectory indicates that the plates of the Pacific Basin participated in the same large-amplitude (∼30°) rotation as continental lithosphere in the 160-145 Ma interval. Such coherent motion of a large majority of the Earth's surface strongly supports the occurrence of TPW, suggesting that a combination of subducting slabs and rising mantle plumes was sufficient to significantly perturb the Earth's inertia tensor in the Late Jurassic.

  14. Improving IQ measurement in intellectual disabilities using true deviation from population norms.

    Science.gov (United States)

    Sansone, Stephanie M; Schneider, Andrea; Bickel, Erika; Berry-Kravis, Elizabeth; Prescott, Christina; Hessl, David

    2014-01-01

    Intellectual disability (ID) is characterized by global cognitive deficits, yet the very IQ tests used to assess ID have limited range and precision in this population, especially for more impaired individuals. We describe the development and validation of a method of raw z-score transformation (based on general population norms) that ameliorates floor effects and improves the precision of IQ measurement in ID using the Stanford Binet 5 (SB5) in fragile X syndrome (FXS; n = 106), the leading inherited cause of ID, and in individuals with idiopathic autism spectrum disorder (ASD; n = 205). We compared the distributional characteristics and Q-Q plots from the standardized scores with the deviation z-scores. Additionally, we examined the relationship between both scoring methods and multiple criterion measures. We found evidence that substantial and meaningful variation in cognitive ability on standardized IQ tests among individuals with ID is lost when converting raw scores to standardized scaled, index and IQ scores. Use of the deviation z- score method rectifies this problem, and accounts for significant additional variance in criterion validation measures, above and beyond the usual IQ scores. Additionally, individual and group-level cognitive strengths and weaknesses are recovered using deviation scores. Traditional methods for generating IQ scores in lower functioning individuals with ID are inaccurate and inadequate, leading to erroneously flat profiles. However assessment of cognitive abilities is substantially improved by measuring true deviation in performance from standardization sample norms. This work has important implications for standardized test development, clinical assessment, and research for which IQ is an important measure of interest in individuals with neurodevelopmental disorders and other forms of cognitive impairment.

  15. True coincidence summing correction and mathematical efficiency modeling of a well detector

    Energy Technology Data Exchange (ETDEWEB)

    Jäderström, H., E-mail: henrik.jaderstrom@canberra.com [CANBERRA Industries Inc., 800 Research Parkway, Meriden, CT 06450 (United States); Mueller, W.F. [CANBERRA Industries Inc., 800 Research Parkway, Meriden, CT 06450 (United States); Atrashkevich, V. [Stroitely St 4-4-52, Moscow (Russian Federation); Adekola, A.S. [CANBERRA Industries Inc., 800 Research Parkway, Meriden, CT 06450 (United States)

    2015-06-01

    True coincidence summing (TCS) occurs when two or more photons are emitted from the same decay of a radioactive nuclide and are detected within the resolving time of the gamma ray detector. TCS changes the net peak areas of the affected full energy peaks in the spectrum and the nuclide activity is rendered inaccurate if no correction is performed. TCS is independent of the count rate, but it is strongly dependent on the peak and total efficiency, as well as the characteristics of a given nuclear decay. The TCS effects are very prominent for well detectors because of the high efficiencies, and make accounting for TCS a necessity. For CANBERRA's recently released Small Anode Germanium (SAGe) well detector, an extension to CANBERRA's mathematical efficiency calibration method (In Situ Object Calibration Software or ISOCS, and Laboratory SOurceless Calibration Software or LabSOCS) has been developed that allows for calculation of peak and total efficiencies for SAGe well detectors. The extension also makes it possible to calculate TCS corrections for well detectors using the standard algorithm provided with CANBERRAS's Spectroscopy software Genie 2000. The peak and total efficiencies from ISOCS/LabSOCS have been compared to MCNP with agreements within 3% for peak efficiencies and 10% for total efficiencies for energies above 30 keV. A sample containing Ra-226 daughters has been measured within the well and analyzed with and without TCS correction and applying the correction factor shows significant improvement of the activity determination for the energy range 46–2447 keV. The implementation of ISOCS/LabSOCS for well detectors offers a powerful tool for efficiency calibration for these detectors. The automated algorithm to correct for TCS effects in well detectors makes nuclide specific calibration unnecessary and offers flexibility in carrying out gamma spectral analysis.

  16. Pseudo and true visible light photocatalytic activity of nanotube titanic acid/graphene composites

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Xiaodong, E-mail: donguser@hotmail.com; Liu, Xiaogang; Xue, Xiaoxiao; Pan, Hui; Zhang, Min; Li, Qiuye; Yu, Laigui; Yang, Jianjun; Zhang, Zhijun [Henan University, Key Laboratory of Ministry of Education for Special Functional Materials (China)

    2013-09-15

    Nanotube titanic acid/graphene (NTA/Gr) composites were prepared by an easy hydrothermal treatment of graphene oxide (GO) and NTA in a mixed solvent of ethanol-water. As-prepared NTA/Gr composites and GO were characterized by means of Fourier transform infrared spectrometry, X-ray diffraction, diffuse-reflection spectrometry, thermal analysis, and transmission electron microscopy. Besides, the photocatalytic activities of as-prepared NTA/Gr composites were evaluated by monitoring the degradation of methyl orange (MO) under visible light irradiation. It has been found that extending hydrothermal reaction time (24 h instead of 3 h) leads to great changes in the morphology and crystal structure of as-prepared composites. Namely, the orthorhombic NTA (ca. 10 nm in diameter) in the composite transformed to anatase TiO{sub 2} particle (ca. 20-30 nm in diameter) while the Gr sheets (with micrometers-long wrinkles) in it transformed to a few Gr fragments (ca. 50 nm in diameter). Correspondingly, the NTA/Gr composite transformed to titanium dioxide/graphene (TiO{sub 2}/Gr) composite. In the meantime, pure GO only has adsorption effect but it has no photocatalytic activity in the visible light region. Nevertheless, increasing Gr ratio results in enhanced visible light absorption capability and photocatalytic activity of NTA/Gr composites as well as the TiO{sub 2}/Gr composites. This demonstrates that the true visible light photocatalytic activity of NTA/Gr composites as well as the TiO{sub 2}/Gr composites for the degradation of MO is not as excellent as expected, and their high apparent activity is attributed to the strong adsorption of MO on the composites.

  17. Pseudo and true visible light photocatalytic activity of nanotube titanic acid/graphene composites

    Science.gov (United States)

    Wang, Xiaodong; Liu, Xiaogang; Xue, Xiaoxiao; Pan, Hui; Zhang, Min; Li, Qiuye; Yu, Laigui; Yang, Jianjun; Zhang, Zhijun

    2013-09-01

    Nanotube titanic acid/graphene (NTA/Gr) composites were prepared by an easy hydrothermal treatment of graphene oxide (GO) and NTA in a mixed solvent of ethanol-water. As-prepared NTA/Gr composites and GO were characterized by means of Fourier transform infrared spectrometry, X-ray diffraction, diffuse-reflection spectrometry, thermal analysis, and transmission electron microscopy. Besides, the photocatalytic activities of as-prepared NTA/Gr composites were evaluated by monitoring the degradation of methyl orange (MO) under visible light irradiation. It has been found that extending hydrothermal reaction time (24 h instead of 3 h) leads to great changes in the morphology and crystal structure of as-prepared composites. Namely, the orthorhombic NTA (ca. 10 nm in diameter) in the composite transformed to anatase TiO2 particle (ca. 20-30 nm in diameter) while the Gr sheets (with micrometers-long wrinkles) in it transformed to a few Gr fragments (ca. 50 nm in diameter). Correspondingly, the NTA/Gr composite transformed to titanium dioxide/graphene (TiO2/Gr) composite. In the meantime, pure GO only has adsorption effect but it has no photocatalytic activity in the visible light region. Nevertheless, increasing Gr ratio results in enhanced visible light absorption capability and photocatalytic activity of NTA/Gr composites as well as the TiO2/Gr composites. This demonstrates that the true visible light photocatalytic activity of NTA/Gr composites as well as the TiO2/Gr composites for the degradation of MO is not as excellent as expected, and their high apparent activity is attributed to the strong adsorption of MO on the composites.

  18. [Multispectral Radiation Algorithm Based on Emissivity Model Constraints for True Temperature Measurement].

    Science.gov (United States)

    Liang, Mei; Sun, Xiao-gang; Luan, Mei-sheng

    2015-10-01

    Temperature measurement is one of the important factors for ensuring product quality, reducing production cost and ensuring experiment safety in industrial manufacture and scientific experiment. Radiation thermometry is the main method for non-contact temperature measurement. The second measurement (SM) method is one of the common methods in the multispectral radiation thermometry. However, the SM method cannot be applied to on-line data processing. To solve the problems, a rapid inversion method for multispectral radiation true temperature measurement is proposed and constraint conditions of emissivity model are introduced based on the multispectral brightness temperature model. For non-blackbody, it can be drawn that emissivity is an increasing function in the interval if the brightness temperature is an increasing function or a constant function in a range and emissivity satisfies an inequality of emissivity and wavelength in that interval if the brightness temperature is a decreasing function in a range, according to the relationship of brightness temperatures at different wavelengths. The construction of emissivity assumption values is reduced from multiclass to one class and avoiding the unnecessary emissivity construction with emissivity model constraint conditions on the basis of brightness temperature information. Simulation experiments and comparisons for two different temperature points are carried out based on five measured targets with five representative variation trends of real emissivity. decreasing monotonically, increasing monotonically, first decreasing with wavelength and then increasing, first increasing and then decreasing and fluctuating with wavelength randomly. The simulation results show that compared with the SM method, for the same target under the same initial temperature and emissivity search range, the processing speed of the proposed algorithm is increased by 19.16%-43.45% with the same precision and the same calculation results.

  19. Neural Correlates of True and False Memory in Mild Cognitive Impairment

    Science.gov (United States)

    Sweeney-Reed, Catherine M.; Riddell, Patricia M.; Ellis, Judi A.; Freeman, Jayne E.; Nasuto, Slawomir J.

    2012-01-01

    The goal of this research was to investigate the changes in neural processing in mild cognitive impairment. We measured phase synchrony, amplitudes, and event-related potentials in veridical and false memory to determine whether these differed in participants with mild cognitive impairment compared with typical, age-matched controls. Empirical mode decomposition phase locking analysis was used to assess synchrony, which is the first time this analysis technique has been applied in a complex cognitive task such as memory processing. The technique allowed assessment of changes in frontal and parietal cortex connectivity over time during a memory task, without a priori selection of frequency ranges, which has been shown previously to influence synchrony detection. Phase synchrony differed significantly in its timing and degree between participant groups in the theta and alpha frequency ranges. Timing differences suggested greater dependence on gist memory in the presence of mild cognitive impairment. The group with mild cognitive impairment had significantly more frontal theta phase locking than the controls in the absence of a significant behavioural difference in the task, providing new evidence for compensatory processing in the former group. Both groups showed greater frontal phase locking during false than true memory, suggesting increased searching when no actual memory trace was found. Significant inter-group differences in frontal alpha phase locking provided support for a role for lower and upper alpha oscillations in memory processing. Finally, fronto-parietal interaction was significantly reduced in the group with mild cognitive impairment, supporting the notion that mild cognitive impairment could represent an early stage in Alzheimer’s disease, which has been described as a ‘disconnection syndrome’. PMID:23118992

  20. Topside Ionogram Scaler With True Height Algorithm (TOPIST): Automated processing of ISIS topside ionograms

    Science.gov (United States)

    Bilitza, Dieter; Huang, Xueqin; Reinisch, Bodo W.; Benson, Robert F.; Hills, H. Kent; Schar, William B.

    2004-02-01

    The United States/Canadian ISIS-1 and ISIS-2 satellites collected several million topside ionograms in the 1960s and 1970s with a multinational network of ground stations that provided good global coverage. However, processing of these ionograms into electron density profiles required time-consuming manual scaling of the traces from the analog ionograms, and as a result, only a few percent of the ionograms had been processed into electron density profiles. In recent years an effort began to digitize the analog recordings to prepare the ionograms for computerized analysis. As of November 2002, approximately 390,000 ISIS-1 and ISIS-2 digital topside-sounder ionograms have been produced. The Topside Ionogram Scaler With True Height Algorithm (TOPIST) program was developed for the automated scaling of the echo traces and for the inversion of these traces into topside electron density profiles. The program is based on the techniques that have been successfully applied in the analysis of ground-based Digisonde ionograms. The TOPIST software also includes an "editing option" for manual scaling of the more difficult ionograms, which could not be scaled during the automated TOPIST run. TOPIST is now successfully scaling ˜60% of the ISIS ionograms, and the electron density profiles are available through the online archive of the National Space Science Data Center at ftp://nssdcftp.gsfc.nasa.gov/spacecraft_data/isis/topside_sounder. This data restoration effort is producing a unique global database of topside electron densities over more than one solar cycle, which will be of particular importance for improvements of topside ionosphere models, especially the International Reference Ionosphere.

  1. Embedded Platform for Automatic Testing and Optimizing of FPGA Based Cryptographic True Random Number Generators

    Directory of Open Access Journals (Sweden)

    M. Varchola

    2009-12-01

    Full Text Available This paper deals with an evaluation platform for cryptographic True Random Number Generators (TRNGs based on the hardware implementation of statistical tests for FPGAs. It was developed in order to provide an automatic tool that helps to speed up the TRNG design process and can provide new insights on the TRNG behavior as it will be shown on a particular example in the paper. It enables to test sufficient statistical properties of various TRNG designs under various working conditions on the fly. Moreover, the tests are suitable to be embedded into cryptographic hardware products in order to recognize TRNG output of weak quality and thus increase its robustness and reliability. Tests are fully compatible with the FIPS 140 standard and are implemented by the VHDL language as an IP-Core for vendor independent FPGAs. A recent Flash based Actel Fusion FPGA was chosen for preliminary experiments. The Actel version of the tests possesses an interface to the Actel’s CoreMP7 softcore processor that is fully compatible with the industry standard ARM7TDMI. Moreover, identical tests suite was implemented to the Xilinx Virtex 2 and 5 in order to compare the performance of the proposed solution with the performance of already published one based on the same FPGAs. It was achieved 25% and 65% greater clock frequency respectively while consuming almost equal resources of the Xilinx FPGAs. On the top of it, the proposed FIPS 140 architecture is capable of processing one random bit per one clock cycle which results in 311.5 Mbps throughput for Virtex 5 FPGA.

  2. Does air gas aesthesiometry generate a true mechanical stimulus for corneal sensitivity measurement?

    Science.gov (United States)

    Nosch, Daniela S; Pult, Heiko; Albon, Julie; Purslow, Christine; Murphy, Paul J

    2018-03-01

    Belmonte Ocular Pain Meter (OPM) air jet aesthesiometry overcomes some of the limitations of the Cochet-Bonnet aesthesiometer. However, for true mechanical corneal sensitivity measurement, the airflow stimulus temperature of the aesthesiometer must equal ocular surface temperature (OST), to avoid additional response from temperature-sensitive nerves. The aim of this study was to determine: (A) the stimulus temperature inducing no or least change in OST; and (B) to evaluate if OST remains unchanged with different stimulus durations and airflow rates. A total of 14 subjects (mean age 25.14 ± 2.18 years; seven women) participated in this clinical cohort study: (A) OST was recorded using an infrared camera (FLIR A310) during the presentation of airflow stimuli, at five temperatures, ambient temperature (AT) +5°C, +10°C, +15°C, +20°C and +30°C, using the OPM aesthesiometer (duration three seconds; over a four millimetre distance; airflow rate 60 ml/min); and (B) OST measurements were repeated with two stimulus temperatures (AT +10°C and +15°C) while varying stimulus durations (three seconds and five seconds) and airflow rates (30, 60, 80 and 100 ml/min). Inclusion criteria were age measures (analysis of variance) and appropriate post-hoc t-tests were applied. (A) Stimulus temperatures of AT +10°C and +15°C induced the least changes in OST (-0.20 ± 0.13°C and 0.08 ± 0.05°C). (B) OST changes were statistically significant with both stimulus temperatures and increased with increasing airflow rates (p air stimulus of the Belmonte OPM because its air jet stimulus with mechanical setting is likely to have a thermal component. Appropriate stimulus selection for an air jet aesthesiometer must incorporate stimulus temperature control that can vary with stimulus duration and airflow rate. © 2017 Optometry Australia.

  3. Cascading value: the true value of advanced data collection solutions can be found in the information

    International Nuclear Information System (INIS)

    Neilson, R.D.

    1999-01-01

    Utilities and other energy related businesses are still trying to find the right gear on the road to realizing the full value potential of the information they collect and manage. The energy industry as a whole has yet to discover the true value of a commodity that is very available in its own backyard, while other companies have done so. By deploying advanced technology, energy related companies are able to collect advanced metering information and put it to use in ways never imagined a decade two or ago. Utilities and their clients can use this information to run their businesses more efficiently or market new valued added products and services to customers. The best vantage point from which to understand and appreciate the new value proposition for meter data and energy use information is to divide the meter into two parts: the client side and the utility side. Breaking it down even further, each side presents two areas of opportunity: the first of which covers applications and practices which enable a utility or client to manage itself better as a business, while the second area covers opportunities to develop and market new services to clients. An account is given of these areas and of how utilizing advanced data collection technology to gather daily, interval and off-schedule reads, along with outage and power quality data, can dramatically extend and increase the value of meter data they collect. By collecting sophisticated energy use data more frequently and efficiently than ever before, today's data collection solutions have transformed this value proposition into bottom-line reality

  4. Prediction of true test scores from observed item scores and ancillary data.

    Science.gov (United States)

    Haberman, Shelby J; Yao, Lili; Sinharay, Sandip

    2015-05-01

    In many educational tests which involve constructed responses, a traditional test score is obtained by adding together item scores obtained through holistic scoring by trained human raters. For example, this practice was used until 2008 in the case of GRE(®) General Analytical Writing and until 2009 in the case of TOEFL(®) iBT Writing. With use of natural language processing, it is possible to obtain additional information concerning item responses from computer programs such as e-rater(®). In addition, available information relevant to examinee performance may include scores on related tests. We suggest application of standard results from classical test theory to the available data to obtain best linear predictors of true traditional test scores. In performing such analysis, we require estimation of variances and covariances of measurement errors, a task which can be quite difficult in the case of tests with limited numbers of items and with multiple measurements per item. As a consequence, a new estimation method is suggested based on samples of examinees who have taken an assessment more than once. Such samples are typically not random samples of the general population of examinees, so that we apply statistical adjustment methods to obtain the needed estimated variances and covariances of measurement errors. To examine practical implications of the suggested methods of analysis, applications are made to GRE General Analytical Writing and TOEFL iBT Writing. Results obtained indicate that substantial improvements are possible both in terms of reliability of scoring and in terms of assessment reliability. © 2015 The British Psychological Society.

  5. THE TRUE FACE OF PRE-COLONIAL AFRICA IN "THINGS FALL APART"

    Directory of Open Access Journals (Sweden)

    Ecevit Bekler

    2014-04-01

    Full Text Available The Nigerian writer Chinua Achebe is known to be one of the most influential African wri­ters and holds an important place in postcolonial studies. His main aim was to reconstruct the wrongly established beliefs, ideas, and thoughts of the Western world regarding Africa. To realize his aim, he made careful selections in his choice of language, which contributed greatly to sharing his observations, ideas, and beliefs with the rest of the world. He wrote his novels in English, believing that doing so would be more powerful in conveying the true face of pre-colonial Africa, rather than in Nigerian, which could not be as effective as the language of the colonizers. Achebe’s complaint was that the history of Africa had mainly been written by white men who did not belong to his continent and who would not judge life there fairly. With his novels, he changed the prejudices of those who had never been to Africa, and he managed to convert the negative ideas and feelings caused by the portrayal of his continent to positive ones. "Things Fall Apart" is a novel whose mission is to portray Africa in a very realistic and authentic environment, contrary to the one-sided point of view of the colonizers. The novel presents us, in very authentic language, with many details about the customs, rituals, daily life practices, ceremonies, beliefs, and even jokes of the African Igbos. Chinua Achebe thus realizes his aim in revealing that African tribes, although regarded as having a primitive life and being very far from civilization, in fact had their own life with traditions and a culture specific to themselves.

  6. Treatment of benign brain lesions True Beam radiosurgery in the first year of experience; Tratamiento de lesiones cerebrales benignas con radiocirugia en el True-Beam: Primer ano de experiencia

    Energy Technology Data Exchange (ETDEWEB)

    Lliso, F.; Carmona, V.; Gimeno, J.; Candela, C.; Bautista, J. A.; Perez-Calatayud, J.

    2015-07-01

    The purpose of the work is analyse the first year of experience in the treatment of injury brain benign with Rapid Arc in the patients treated in a throttle True Beam STX with radiosurgery who achieved an adequate level of efficiency and accuracy. (Author)

  7. DK crush (double-kissing and double-crush) technique for treatment of true coronary bifurcation lesions: illustration and comparison with classic crush.

    Science.gov (United States)

    Chen, Shaoliang; Zhang, Junjie; Ye, Fei; Zhu, Zhongsheng; Lin, Song; Shan, Shoujie; Kwan, Tak W

    2007-04-01

    Classic crush has a lower success rate compared to final kissing balloon inflation (FKBI). We previously reported the double-kissing (DK) crush technique that involves double-kissing along with double-crushing for the treatment of true bifurcation coronary lesions in 2005. This is a consecutive, nonrandomized, open-label study. Eighty-eight consecutive patients with single, true coronary bifurcation lesions according to Lefevre Classification2 and side branch diameter >2.0 mm were enrolled. The first 44 patients (from October 2004 to January 2005) were assigned to the classic crush treatment arm and the next 44 patients (from February 2005 to June 2005) were assigned to the DK crush technique arm, respectively. Data within 30 days were analyzed. Patients in the DK crush group, compared to those in classic crush group, were characterized by longer lesion length in the side branch (13.5 +/- 3.4 mm vs 7.8 +/- 3.1 mm; p DK crush group, as well as longer lesion length in the main vessel (24.3 +/- 8.6 mm vs 21.1 +/- 7.3 mm), though without significant differences (p >0.05). Subacute stent thrombosis was detected in 2 patients with failure of FKBI in the classic crush group (4.3%). In addition, patients in the classic crush group were characterized by a smaller minimum lumen diameter (MLD) at the side branch ostium (2.74 +/- 0.12 mm vs 3.01 +/- 0.13 mm; p DK crush has the potential to improve the clinical outcome in patients with coronary bifurcation lesions. Further randomized, prospective, multicenter studies are required to confirm these differences between the classic crush and DK crush techniques.

  8. The Recombination Mechanism and True Green Amplified Spontaneous Emission in CH3NH3PbBr3 Perovskite

    KAUST Repository

    Priante, Davide

    2015-01-01

    . M. Bakr, and B. S. Ooi, "The recombination mechanisms leading to amplified spontaneous emission at the true-green wavelength in CH3NH3PbBr3 perovskites", Applied Physics Letters, 106, 081902, 2015. DOI: 10.1063/1.4913463

  9. Deriving the true mass of an unresolved Brown Dwarf companion to an M-Dwarf with AO aided astrometry*

    Directory of Open Access Journals (Sweden)

    Kürster M.

    2011-07-01

    Full Text Available From radial velocity (RV detections alone one does not get all orbital parameters needed to derive the true mass of a non-transiting, unresolved substellar companion to a star. Additional astrometric measurements are needed to calculate the inclination and the longitude of the ascending node. Until today only few true substellar companion masses have been determined by this method with the HST fine guidance sensor [1, 2]. We aim to derive the true mass of a brown dwarf candidate companion to an early M 2.5V dwarf with groundbased high-resolution astrometry aided by adaptive optics. We found this unique brown dwarf desert object, whose distance to the host star is only 0.42 AU, in our UVES precision RV survey of M dwarfs, inferring a minimum companion mass of 27 Jupiter masses [3]. Combining the data with HIPPARCOS astrometry, we found a probability of only 2.9% that the companion is stellar. We therefore observed the host star together with a reference star within a monitoring program with VLT/NACO to derive the true mass of the companion and establish its nature (brown dwarf vs. star. Simultaneous observations of a reference field in a globular cluster are performed to determine the stability of the adaptive optics (AO plus detector system and check its suitability for such high-precision astrometric measurements over several epochs which are needed to find and analyse extrasolar planet systems.

  10. Differences between true mean temperatures and means calculated with four different approaches: a case study from three Croatian stations

    Science.gov (United States)

    Bonacci, Ognjen; Željković, Ivana

    2018-01-01

    Different countries use varied methods for daily mean temperature calculation. None of them assesses precisely the true daily mean temperature, which is defined as the integral of continuous temperature measurements in a day. Of special scientific as well as practical importance is to find out how temperatures calculated by different methods and approaches deviate from the true daily mean temperature. Five mean daily temperatures were calculated (T0, T1, T2, T3, T4) using five different equations. The mean of 24-h temperature observations during the calendar day is accepted to represent the true, daily mean T0. The differences Δ i between T0 and four other mean daily temperatures T1, T2, T3, and T4 were calculated and analysed. In the paper, analyses were done with hourly data measured in a period from 1 January 1999 to 31 December 2014 (149,016 h, 192 months and 16 years) at three Croatian meteorological stations. The stations are situated in distinct climatological areas: Zagreb Grič in a mild climate, Zavižan in the cold mountain region and Dubrovnik in the hot Mediterranean. Influence of fog on the temperature is analysed. Special attention is given to analyses of extreme (maximum and minimum) daily differences occurred at three analysed stations. Selection of the fixed local hours, which is in use for calculation of mean daily temperature, plays a crucial role in diminishing of bias from the true daily temperature.

  11. Authentication of true cinnamon (Cinnamon verum) utilising direct analysis in real time (DART)-QWToF-MS

    Science.gov (United States)

    The use of cinnamon as a spice and 'avouring agent is widespread throughout the world. Many different species of plants are commonly referred to as ‘cinnamon’. ‘True cinnamon’ refers to the dried inner bark of Cinnamomum verum J. S. Presl (syn. C zeylanicum) (Lauraceae). Other ‘cinnamon’ species, C....

  12. Multilocus phylogenetic analysis of true morels (Morchella) reveals high levels of endemics in Turkey relative ot other regions of Europe

    Science.gov (United States)

    The present study was conducted to better understand how the phylogenetic diversity of true morels (Morchella) in Turkey compares with species found in other regions of the world. The current research builds on our recently published survey of 10 Turkish provinces and another of the world in which D...

  13. True morels (Morchella, Pezizales) of Europe and North America: evolutionary relationships inferred from multilocus data and a unified taxonomy

    Science.gov (United States)

    Applying early names, 29 with or without original material, to genealogical species is challenging. For morels this task is especially difficult because of high morphological stasis and high plasticity of apothecium color and shape. Here, we propose a nomenclatural revision of true morels (Morchella...

  14. Two new species of true morels from Newfoundland and Labrador: cosmopolitan Morchella eohespera and parochial M. laurentiana

    Science.gov (United States)

    Morphological and molecular phylogenetic studies of true morels (Morchella) in the Canadian province of Newfoundland and Labrador (NL) resulted in the surprising discovery of two undescribed species in the M. elata clade, which we initially distinguished by the informal designations Mel-19 and Mel-3...

  15. Effects of Different Types of True-False Questions on Memory Awareness and Long-Term Retention

    Science.gov (United States)

    Schaap, Lydia; Verkoeijen, Peter; Schmidt, Henk

    2014-01-01

    This study investigated the effects of two different true-false questions on memory awareness and long-term retention of knowledge. Participants took four subsequent knowledge tests on curriculum learning material that they studied at different retention intervals prior to the start of this study (i.e. prior to the first test). At the first and…

  16. How Much Do You Know about Teen Sexual Behavior? A True-False Quiz. Fact Sheet. Publication 2008-31

    Science.gov (United States)

    Holcombe, Emily; Peterson, Kristen; Manlove, Jennifer

    2008-01-01

    Despite media attention to teen sexual behavior and public concern about its consequences, the public is surprisingly ill-informed or misinformed on the subject. Yet without the facts, it is difficult to develop effective approaches to curb risky sexual behaviors and prevent teen pregnancy and STI transmission. This paper presents a true or false…

  17. True progress is tobacco-free campaign: engaging civil society to implement FCTC Article 5.3 in the Philippines

    Directory of Open Access Journals (Sweden)

    Ralph Emerson Degollacion

    2018-03-01

    The campaign is not yet over. It´s has taught us to be creative, flexible, and patient. Educating civil society about the true intentions of the tobacco industry is a fight worth pursuing. Sustained financial and technical support is needed in order to reach more groups in the country.

  18. A True-Color Sensor and Suitable Evaluation Algorithm for Plant Recognition.

    Science.gov (United States)

    Schmittmann, Oliver; Schulze Lammers, Peter

    2017-08-08

    Plant-specific herbicide application requires sensor systems for plant recognition and differentiation. A literature review reveals a lack of sensor systems capable of recognizing small weeds in early stages of development (in the two- or four-leaf stage) and crop plants, of making spraying decisions in real time and, in addition, are that are inexpensive and ready for practical use in sprayers. The system described in this work is based on free cascadable and programmable true-color sensors for real-time recognition and identification of individual weed and crop plants. The application of this type of sensor is suitable for municipal areas and farmland with and without crops to perform the site-specific application of herbicides. Initially, databases with reflection properties of plants, natural and artificial backgrounds were created. Crop and weed plants should be recognized by the use of mathematical algorithms and decision models based on these data. They include the characteristic color spectrum, as well as the reflectance characteristics of unvegetated areas and areas with organic material. The CIE-Lab color-space was chosen for color matching because it contains information not only about coloration (a- and b-channel), but also about luminance (L-channel), thus increasing accuracy. Four different decision making algorithms based on different parameters are explained: (i) color similarity (ΔE); (ii) color similarity split in ΔL, Δa and Δb; (iii) a virtual channel 'd' and (iv) statistical distribution of the differences of reflection backgrounds and plants. Afterwards, the detection success of the recognition system is described. Furthermore, the minimum weed/plant coverage of the measuring spot was calculated by a mathematical model. Plants with a size of 1-5% of the spot can be recognized, and weeds in the two-leaf stage can be identified with a measuring spot size of 5 cm. By choosing a decision model previously, the detection quality can be increased

  19. Anomalous Late Jurassic motion of the Pacific Plate with implications for true polar wander

    Science.gov (United States)

    Fu, R. R.; Kent, D.

    2017-12-01

    True polar wander, or TPW, is the rotation of the entire mantle-crust system that results in simultaneous change in latitude and orientation for all lithospheric plates. One of the most recent candidate TPW events consists of a 30˚ rotation during Late Jurassic time (160 - 145 Ma). However, existing paleomagnetic documentation of this event derives exclusively from continental studies. Because all major landmasses except China were connected directly or via spreading centers in the Late Jurassic, the velocities of these continents were mutually constrained and their motion as a group over the underlying mantle would be indistinguishable from TPW using only continental data. On the other hand, plates of the Pacific Basin constituted a kinematically independent domain, interfacing with continents at subduction zones and slip-strike boundaries. Coherent motion of both Pacific Basin and continental plates would therefore indicate uniform motion of virtually the entire lithosphere, providing a means to distinguish TPW from continental drift. We performed thermal demagnetization on remaining samples from Ocean Drilling Program (ODP) Site 801B, which were cored from the oldest sampled oceanic crust in the Western Pacific, to determine its change in paleolatitude during the Late Jurassic and Early Cretaceous (167 - 134 Ma). We find that the Pacific Plate likely underwent a steady southward drift during this time period, consistent with previous results from magnetic anomalies, except for an episode of northward motion between Oxfordian and Tithonian time (161 - 147 Ma). Although the amplitude of this northward shift is subject to significant uncertainty due to the sparse recovery of core samples, the trajectory of the Pacific Plate is most simply explained by TPW in the 160 - 145 Ma interval as inferred from continental data. Furthermore, such an interpretation is consistent with the sense of shear inferred at the Farallon-North American Plate boundary, whereas uniform

  20. True tracheal bronchus: Classification and anatomical relationship on multi-detector computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun Jeong; Kim, Young Tong; Jou, Sung Shick; Lee, Woong Hee [Dept. of Radiology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan (Korea, Republic of)

    2017-04-15

    To propose the imaging classification of true tracheal bronchus (TTB) on multi-detector computed tomography (MDCT), and to evaluate its anatomical relationship with surrounding structures. This study included 44 patients who were diagnosed with TTB on MDCT for 6 years. We classified TTB into five types, based on the existence of the right upper lobe bronchus originating from the right main bronchus and the number of segmental bronchi of TTB. We analyzed the site of origin and the running direction of TTB based on its anatomical relationship with surrounding structures and some ancillary findings. The imaging classification of TTB included Type I (47.7%), Type II (13.6%), Type III (11.4%), Type IV (25.0%), and Type V (2.0%). According to the site of origin of TTB, below the aortic arch (52.3%) and at the level of the aortic arch (43.1%) were the two main sites of origin, whereas the frequency of the site of origin above the azygos arch, at the level of the azygos arch, and below the azygos arch was 27.3%, 38.6%, and 34.1%, respectively. Considering both aortic and azygos arches, below the aortic arch and below the azygos arch were the most common sites of origin (27.3%). With respect to the running direction of TTB, in all cases, TTB passed below the azygos arch to the right upper lobe. There was no statistically significant (p > 0.05) difference in age or sex between types of TTB. Ancillary findings included tracheal stenosis (n = 2), narrowing of the right main bronchus (n = 2), luminal narrowing of TTB and bronchiectasis at the distal portion (n = 1), and a highly located azygos arch above the aortic arch (n = 2). The proposed imaging classification of TTB and its anatomical relationship with surrounding structures will improve our understanding of various imaging features and embryological development of TTB. Radiologists should pay careful attention to evaluation of the airway including the trachea on thoracic imaging.

  1. True tracheal bronchus: Classification and anatomical relationship on multi-detector computed tomography

    International Nuclear Information System (INIS)

    Kim, Hyun Jeong; Kim, Young Tong; Jou, Sung Shick; Lee, Woong Hee

    2017-01-01

    To propose the imaging classification of true tracheal bronchus (TTB) on multi-detector computed tomography (MDCT), and to evaluate its anatomical relationship with surrounding structures. This study included 44 patients who were diagnosed with TTB on MDCT for 6 years. We classified TTB into five types, based on the existence of the right upper lobe bronchus originating from the right main bronchus and the number of segmental bronchi of TTB. We analyzed the site of origin and the running direction of TTB based on its anatomical relationship with surrounding structures and some ancillary findings. The imaging classification of TTB included Type I (47.7%), Type II (13.6%), Type III (11.4%), Type IV (25.0%), and Type V (2.0%). According to the site of origin of TTB, below the aortic arch (52.3%) and at the level of the aortic arch (43.1%) were the two main sites of origin, whereas the frequency of the site of origin above the azygos arch, at the level of the azygos arch, and below the azygos arch was 27.3%, 38.6%, and 34.1%, respectively. Considering both aortic and azygos arches, below the aortic arch and below the azygos arch were the most common sites of origin (27.3%). With respect to the running direction of TTB, in all cases, TTB passed below the azygos arch to the right upper lobe. There was no statistically significant (p > 0.05) difference in age or sex between types of TTB. Ancillary findings included tracheal stenosis (n = 2), narrowing of the right main bronchus (n = 2), luminal narrowing of TTB and bronchiectasis at the distal portion (n = 1), and a highly located azygos arch above the aortic arch (n = 2). The proposed imaging classification of TTB and its anatomical relationship with surrounding structures will improve our understanding of various imaging features and embryological development of TTB. Radiologists should pay careful attention to evaluation of the airway including the trachea on thoracic imaging

  2. Splitting Terraced Houses Into Single Units Using Oblique Aerial Imagery

    Science.gov (United States)

    Dahlke, D.

    2017-05-01

    This paper introduces a method to subdivide complex building structures like terraced houses into single house units comparable to units available in a cadastral map. 3D line segments are detected with sub-pixel accuracy in traditional vertical true orthomosaics as well as in innovative oblique true orthomosaics and their respective surface models. Hereby high gradient strengths on roofs as well as façades are taken into account. By investigating the coplanarity and frequencies within a set of 3D line segments, individual cut lines for a building complex are found. The resulting regions ideally describe single houses and thus the object complexity is reduced for subsequent topological, semantical or geometrical considerations. For the chosen study area with 70 buidling outlines a hit rate of 80% for cut lines is achieved.

  3. TrueAllele casework on Virginia DNA mixture evidence: computer and manual interpretation in 72 reported criminal cases.

    Directory of Open Access Journals (Sweden)

    Mark W Perlin

    Full Text Available Mixtures are a commonly encountered form of biological evidence that contain DNA from two or more contributors. Laboratory analysis of mixtures produces data signals that usually cannot be separated into distinct contributor genotypes. Computer modeling can resolve the genotypes up to probability, reflecting the uncertainty inherent in the data. Human analysts address the problem by simplifying the quantitative data in a threshold process that discards considerable identification information. Elevated stochastic threshold levels potentially discard more information. This study examines three different mixture interpretation methods. In 72 criminal cases, 111 genotype comparisons were made between 92 mixture items and relevant reference samples. TrueAllele computer modeling was done on all the evidence samples, and documented in DNA match reports that were provided as evidence for each case. Threshold-based Combined Probability of Inclusion (CPI and stochastically modified CPI (mCPI analyses were performed as well. TrueAllele's identification information in 101 positive matches was used to assess the reliability of its modeling approach. Comparison was made with 81 CPI and 53 mCPI DNA match statistics that were manually derived from the same data. There were statistically significant differences between the DNA interpretation methods. TrueAllele gave an average match statistic of 113 billion, CPI averaged 6.68 million, and mCPI averaged 140. The computer was highly specific, with a false positive rate under 0.005%. The modeling approach was precise, having a factor of two within-group standard deviation. TrueAllele accuracy was indicated by having uniformly distributed match statistics over the data set. The computer could make genotype comparisons that were impossible or impractical using manual methods. TrueAllele computer interpretation of DNA mixture evidence is sensitive, specific, precise, accurate and more informative than manual

  4. True Molecular Scale Visualization of Variable Clustering Properties of Ryanodine Receptors

    Directory of Open Access Journals (Sweden)

    Isuru Jayasinghe

    2018-01-01

    Full Text Available Summary: Signaling nanodomains rely on spatial organization of proteins to allow controlled intracellular signaling. Examples include calcium release sites of cardiomyocytes where ryanodine receptors (RyRs are clustered with their molecular partners. Localization microscopy has been crucial to visualizing these nanodomains but has been limited by brightness of markers, restricting the resolution and quantification of individual proteins clustered within. Harnessing the remarkable localization precision of DNA-PAINT (<10 nm, we visualized punctate labeling within these nanodomains, confirmed as single RyRs. RyR positions within sub-plasmalemmal nanodomains revealed how they are organized randomly into irregular clustering patterns leaving significant gaps occupied by accessory or regulatory proteins. RyR-inhibiting protein junctophilin-2 appeared highly concentrated adjacent to RyR channels. Analyzing these molecular maps showed significant variations in the co-clustering stoichiometry between junctophilin-2 and RyR, even between nearby nanodomains. This constitutes an additional level of complexity in RyR arrangement and regulation of calcium signaling, intrinsically built into the nanodomains. : Jayasinghe et al. resolve the distribution of single ryanodine receptors (RyRs within intracellular signaling domains in cardiac myocytes with DNA-PAINT, a super-resolution microscopy approach. Individual RyRs are resolved within irregular cluster arrays. Quantitative imaging reveals significant variation in the co-clustering stoichiometry between RyRs and the regulatory protein junctophilin-2. Keywords: nanodomains, DNA-PAINT, single-molecule localization microscopy, ryanodine receptor, super-resolution imaging, junctophilin, heart

  5. Dissecting stem cell differentiation using single cell expression profiling

    OpenAIRE

    Moignard, Victoria Rachel; Göttgens, Berthold

    2016-01-01

    Many assumptions about the way cells behave are based on analyses of populations. However, it is now widely recognized that even apparently pure populations can display a remarkable level of heterogeneity. This is particularly true in stem cell biology where it hinders our understanding of normal development and the development of strategies for regenerative medicine. Over the past decade technologies facilitating gene expression analysis at the single cell level have become widespread, provi...

  6. A True Proteus: A history of energy conservation in German science and culture, 1847-1914

    Science.gov (United States)

    Wegener, F. D. A.

    2009-11-01

    This thesis follows the career of the law of energy conservation in German science and culture between 1847 and 1914. There is an interesting contrast between the initial reception of Hermann Helmholtz’ 1847 treatise ‘Über die Erhaltung der Kraft’, which was rejected by the editor of the Annalen der Physik, and its later status as a classic of science. ‘Energy’ was the shared concept of the disciplines. It was used by physiologists, physicists, psychologists, sociologists and philosophers. Moreover, the law of energy conservation also made a huge cultural impact. The period around 1900 has justly been called an energetic era. Why did the law of energy conservation become such a universal success? The obvious way to explain this success would be to say: because it is true, and subsequently comment upon its great scientific value. This thesis adopts a different perspective. It adopts Wittgenstein’s definition of meaning as use in language. Consequently, the meaning of the law is only referred to in relation to the way in which it was put to use in communicative practice. From this perspective it is immediately evident that the understanding of the law of energy conservation was subject to considerable change. Helmholtz initially conceptualized the law in terms of atoms and forces; Gustav Kirchhoff and Ernst Mach, rejected atoms and forces as hypothetical entities and they preferred to use the more mundane concept of work instead; Wilhelm Ostwald, finally, thought of energy as an immaterial substance. This thesis meticulously follows the changes in use and understanding to which the law was subject as it penetrated German science and culture. Communication and interests, rather than natural essences, are the central explanatory concepts of the thesis. From 1847 onwards Helmholtz and Du Bois-Reymond actively sought to spread the law of energy conservation among their colleagues and the general public. They told their fellow physiologists, for example, that

  7. What’s the Gist? The influence of schemas on the neural correlates underlying true and false memories

    Science.gov (United States)

    Webb, Christina E.; Turney, Indira C.; Dennis, Nancy A.

    2017-01-01

    The current study used a novel scene paradigm to investigate the role of encoding schemas on memory. Specifically, the study examined the influence of a strong encoding schema on retrieval of both schematic and non-schematic information, as well as false memories for information associated with the schema. Additionally, the separate roles of recollection and familiarity in both veridical and false memory retrieval were examined. The study identified several novel results. First, while many common neural regions mediated both schematic and non-schematic retrieval success, schematic recollection exhibited greater activation in visual cortex and hippocampus, regions commonly shown to mediate detailed retrieval. More effortful cognitive control regions in the prefrontal and parietal cortices, on the other hand, supported non-schematic recollection, while lateral temporal cortices supported familiarity-based retrieval of non-schematic items. Second, both true and false recollection, as well as familiarity, were mediated by activity in left middle temporal gyrus, a region associated with semantic processing and retrieval of schematic gist. Moreover, activity in this region was greater for both false recollection and false familiarity, suggesting a greater reliance on lateral temporal cortices for retrieval of illusory memories, irrespective of memory strength. Consistent with previous false memory studies, visual cortex showed increased activity for true compared to false recollection, suggesting that visual cortices are critical for distinguishing between previously viewed targets and related lures at retrieval. Additionally, the absence of common visual activity between true and false retrieval suggests that, unlike previous studies utilizing visual stimuli, when false memories are predicated on schematic gist and not perceptual overlap, there is little reliance on visual processes during false memory retrieval. Finally, the medial temporal lobe exhibited an

  8. Measurement of true ileal calcium digestibility in meat and bone meal for broiler chickens using the direct method.

    Science.gov (United States)

    Anwar, M N; Ravindran, V; Morel, P C H; Ravindran, G; Cowieson, A J

    2016-01-01

    The objective of the study that is presented herein was to determine the true ileal calcium (Ca) digestibility in meat and bone meal (MBM) for broiler chickens using the direct method. Four MBM samples (coded as MBM-1, MBM-2, MBM-3 and MBM-4) were obtained and analyzed for nutrient composition, particle size distribution and bone to soft tissue ratio. The Ca concentrations of MBM-1, MBM-2, MBM-3 and MBM-4 were determined to be 71, 118, 114 and 81 g/kg, respectively. The corresponding geometric mean particle diameters and bone to soft tissue ratios were 0.866, 0.622, 0.875 and 0.781 mm, and 1:1.49, 1:0.98, 1:0.92 and 1:1.35, respectively. Five experimental diets, including four diets with similar Ca concentration (8.3 g/kg) from each MBM and a Ca and phosphorus-free diet, were developed. Meat and bone meal served as the sole source of Ca in the MBM diets. Titanium dioxide (3 g/kg) was incorporated in all diets as an indigestible marker. Each experimental diet was randomly allotted to six replicate cages (eight birds per cage) and offered from d 28 to 31 post-hatch. Apparent ileal Ca digestibility was calculated by the indicator method and corrected for ileal endogenous Ca losses to determine the true ileal Ca digestibility. Ileal endogenous Ca losses were determined to be 88 mg/kg dry matter intake. True ileal Ca digestibility coefficients of MBM-1, MBM-2, MBM-3 and MBM-4 were determined to be 0.560, 0.446, 0.517 and 0.413, respectively. True Ca digestibility of MBM-1 was higher (P 0.05) to that of MBM-3. True Ca digestibility of MBM-2 was similar (P > 0.05) to MBM-3 and MBM-4, while that of MBM-3 was higher (P digestibility in feed ingredients and that Ca in MBM is not highly available as often assumed. The variability in true Ca digestibility of MBM samples could not be attributed to Ca content, percentage bones or particle size. © 2015 Poultry Science Association Inc.

  9. Final report of the TRUE Block Scale project. 4. Synthesis of flow, transport and retention in the block scale

    Energy Technology Data Exchange (ETDEWEB)

    Winberg, Anders [Conterra AB (Sweden); Andersson, Peter; Byegaard, Johan [Geosigma AB (Sweden)] [and others

    2003-03-01

    The TRUE Block Scale project was performed at the Aespoe Hard Rock laboratory as an international partnership funded by ANDRA, ENRESA, JNC, Nirex, Posiva and SKB. The project, initiated mid 1996, was divided in a series of defined stages; Scoping Stage, Preliminary Characterisation Stage, Detailed Characterisation Stage, Tracer Test Stage and the Evaluation and Reporting Stage. The specific objectives were to: 1) increase understanding of tracer transport in a fracture network and improve predictive capabilities, 2) assess the importance of tracer retention mechanisms (diffusion and sorption) in a fracture network, and 3) assess the link between flow and transport data as a means for predicting transport phenomena. Characterisation in included drilling, core logging, borehole imaging, borehole radar, 3D seismic surveys, hydraulic tests (flow logging, single hole tests, cross-hole interference tests), tracer dilution tests, hydrogeochemical analyses of groundwater samples and various types of mineralogical, geochemical and petrophysical measurements on drill core samples. Drilling and characterisation of each new borehole was followed by analysis and decision with regards to need and geometry of a subsequent borehole. The main set of tools for determining the conductive geometry and the hydro-structural model was a combination of borehole television (BIPS), high resolution flow logging and pressure responses from drilling and cross-hole interference tests. The constructed hydro-structural model was made up of a set of deterministic sub-vertical structures mainly oriented northwest. Hydraulic features not part of the deterministic set were included in a stochastic background fracture population. Material properties and boundary conditions were also assigned to the developed model. Characteristics and properties measured in the laboratory were integrated in generalised microstructural models. Hypotheses formulated in relation to defined basic questions were addressed

  10. Final report of the TRUE Block Scale project. 4. Synthesis of flow, transport and retention in the block scale

    International Nuclear Information System (INIS)

    Winberg, Anders; Andersson, Peter; Byegaard, Johan

    2003-03-01

    The TRUE Block Scale project was performed at the Aespoe Hard Rock laboratory as an international partnership funded by ANDRA, ENRESA, JNC, Nirex, Posiva and SKB. The project, initiated mid 1996, was divided in a series of defined stages; Scoping Stage, Preliminary Characterisation Stage, Detailed Characterisation Stage, Tracer Test Stage and the Evaluation and Reporting Stage. The specific objectives were to: 1) increase understanding of tracer transport in a fracture network and improve predictive capabilities, 2) assess the importance of tracer retention mechanisms (diffusion and sorption) in a fracture network, and 3) assess the link between flow and transport data as a means for predicting transport phenomena. Characterisation in included drilling, core logging, borehole imaging, borehole radar, 3D seismic surveys, hydraulic tests (flow logging, single hole tests, cross-hole interference tests), tracer dilution tests, hydrogeochemical analyses of groundwater samples and various types of mineralogical, geochemical and petrophysical measurements on drill core samples. Drilling and characterisation of each new borehole was followed by analysis and decision with regards to need and geometry of a subsequent borehole. The main set of tools for determining the conductive geometry and the hydro-structural model was a combination of borehole television (BIPS), high resolution flow logging and pressure responses from drilling and cross-hole interference tests. The constructed hydro-structural model was made up of a set of deterministic sub-vertical structures mainly oriented northwest. Hydraulic features not part of the deterministic set were included in a stochastic background fracture population. Material properties and boundary conditions were also assigned to the developed model. Characteristics and properties measured in the laboratory were integrated in generalised microstructural models. Hypotheses formulated in relation to defined basic questions were addressed

  11. Particle size for greatest penetration of HEPA filters - and their true efficiency

    International Nuclear Information System (INIS)

    da Roza, R.A.

    1982-01-01

    The particle size that most greatly penetrates a filter is a function of filter media construction, aerosol density, and air velocity. In this paper the published results of several experiments are compared with a modern filtration theory that predicts single-fiber efficiency and the particle size of maximum penetration. For high-efficiency particulate air (HEPA) filters used under design conditions this size is calculated to be 0.21 μm diam. This is in good agreement with the experimental data. The penetration at 0.21 μm is calculated to be seven times greater than at the 0.3 μm used for testing HEPA filters. Several mechanisms by which filters may have a lower efficiency in use than when tested are discussed

  12. Equivalent to Represent Inertial and Primary Frequency Control Effects of an External System

    DEFF Research Database (Denmark)

    Weckesser, Johannes Tilman Gabriel; Van Cutsem, Thierry

    2017-01-01

    This paper presents a novel equivalent, which is suitable for simulation of inertial and primary frequency control effects. In the model reduction procedure, dynamic power injectors are used to replace the external system and to mimic its dynamic behavior. The parameters of the equivalents...... are tuned with a simple approach presented in this paper. The effectiveness of the proposed method is demonstrated on a modified version of the ENTSO-E Dynamic Study Model. The results show that the system frequency response of the unreduced system is retained and a speedup of the simulations of around 4...

  13. Statistical Mechanics of On-line Learning When a Moving Teacher Goes around an Unlearnable True Teacher

    Science.gov (United States)

    Urakami, Masahiro; Miyoshi, Seiji; Okada, Masato

    2007-04-01

    In the framework of on-line learning, a learning machine might move around a teacher due to the differences in structures or output functions between the teacher and the learning machine. In this paper we analyze the generalization performance of a new student supervised by a moving machine. A model composed of a fixed true teacher, a moving teacher, and a student is treated theoretically using statistical mechanics, where the true teacher is a nonmonotonic perceptron and the others are simple perceptrons. Calculating the generalization errors numerically, we show that the generalization errors of a student can temporarily become smaller than that of a moving teacher and can reach the lowest value, even if the student only uses examples from the moving teacher. However, the generalization error of the student eventually becomes the same value with that of the moving teacher. This behavior is qualitatively different from that of a linear model.

  14. Culinary Herbs and Spices: Their Bioactive Properties, the Contribution of Polyphenols and the Challenges in Deducing Their True Health Benefits

    Science.gov (United States)

    Opara, Elizabeth I.; Chohan, Magali

    2014-01-01

    Herbs and spices have been used for both culinary and medicinal purposes for centuries. Over the last decade, research into their role as contributors of dietary polyphenols, known to possess a number of properties associated with reducing the risk of developing chronic non-communicable diseases, has increased. However, bearing in mind how these foods are consumed, normally in small quantities and in combination with other foods, it is unclear what their true benefit is from a health perspective. The aim of this review is to use the literature to discuss how preparative and digestive processes, bioavailability and interactions between foods may influence the bioactive properties of these foods, and whether or not polyphenols are responsible for these properties. Furthermore, this review aims to highlight the challenges that need to be addressed so as to determine the true benefits of these foods and the mechanisms of action that underpin their purported efficacy. PMID:25340982

  15. Chernobyl, the true, the false and the uncertain; Tchernobyl: le vrai, le faux et l'incertain

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    This work makes the part between the true and the false information in France about the Chernobyl accident that have been read in different newspapers during the last years. This document is divide in three parts: what is true, what is false, what is uncertain. In each part are noticed extracts from newspapers face to the synthesis of thoughts about them. It is the fourth edition, the first one was in April 1990, the second one was in 1992 after a report from IAEA on the radiological consequences, the third edition was born in 1994 with the emergence of thyroid cancers especially among children, this fourth edition of 1996 takes into account the sanitary report given by the World Health Organisation experts in 1995. It confirms the progression of thyroid cancers and the absence of any other cancer as well leukemia. (N.C.)

  16. True or false? Memory is differentially affected by stress-induced cortisol elevations and sympathetic activity at consolidation and retrieval.

    Science.gov (United States)

    Smeets, Tom; Otgaar, Henry; Candel, Ingrid; Wolf, Oliver T

    2008-11-01

    Adrenal stress hormones released in response to acute stress may yield memory-enhancing effects when released post-learning and impairing effects at memory retrieval, especially for emotional memory material. However, so far these differential effects of stress hormones on the various memory phases for neutral and emotional memory material have not been demonstrated within one experiment. This study investigated whether, in line with their effects on true memory, stress and stress-induced adrenal stress hormones affect the encoding, consolidation, and retrieval of emotional and neutral false memories. Participants (N=90) were exposed to a stressor before encoding, during consolidation, before retrieval, or were not stressed and then were subjected to neutral and emotional versions of the Deese-Roediger-McDermott word list learning paradigm. Twenty-four hours later, recall of presented words (true recall) and non-presented critical lure words (false recall) was assessed. Results show that stress exposure resulted in superior true memory performance in the consolidation stress group and reduced true memory performance in the retrieval stress group compared to the other groups, predominantly for emotional words. These memory-enhancing and memory-impairing effects were strongly related to stress-induced cortisol and sympathetic activity measured via salivary alpha-amylase levels. Neutral and emotional false recall, on the other hand, was neither affected by stress exposure, nor related to cortisol and sympathetic activity following stress. These results demonstrate the importance of stress-induced hormone-related activity in enhancing memory consolidation and in impairing memory retrieval, in particular for emotional memory material.

  17. Managerial Objectives of the Annual Financial Statements. True and Fair View or „Users, Be Careful!”

    OpenAIRE

    Alina Teodora Ciuhureanu; Nicolae Balteş; Hortensia Gorski

    2009-01-01

    The financial statements represent the less expensive and the most widely spread managerial communication method. Starting from this aspect, the paper shows the managerial usefulness of the information offered by the financial statements. But, in order to take reality, and not „creativity” based decisions, the financial statements must offer a true and fair view of the company, the managers’ opinion regarding this matter being captured, through a selective research.

  18. Characterization of the first true coaxial 18-fold segmented n-type prototype HPGe detector for the gerda project

    International Nuclear Information System (INIS)

    Abt, I.; Caldwell, A.; Gutknecht, D.; Kroeninger, K.; Lampert, M.; Liu, X.; Majorovits, B.; Quirion, D.; Stelzer, F.; Wendling, P.

    2007-01-01

    The first true coaxial 18-fold segmented n-type HPGe prototype detector produced by Canberra-France for the GERDA neutrinoless double beta-decay project was tested both at Canberra-France and at the Max-Planck-Institut fur Physik in Munich. The main characteristics of the detector are given and measurements concerning detector properties are described. A novel method to establish contacts between the crystal and a Kapton cable is presented

  19. What is a True Gamer? The Male Gamer Stereotype and the Marginalization of Women in Video Game Culture

    OpenAIRE

    Paaßen, Benjamin; Morgenroth, Thekla; Stratemeyer, Michelle

    2017-01-01

    Women and men play video games in approximately equal numbers. Despite this, video gaming is still strongly associated with the male gender. A common justification for this stereotype is that, while women might play games, they should not be considered "true" or "hard-core" gamers because they play more casually and less skillfully compared to their male counterparts. In this contribution, we review the existing literature on gender and gaming to investigate the male gamer stereotype in terms...

  20. Authentication of true cinnamon (Cinnamon verum) utilising direct analysis in real time (DART)-QToF-MS.

    Science.gov (United States)

    Avula, Bharathi; Smillie, Troy J; Wang, Yan-Hong; Zweigenbaum, Jerry; Khan, Ikhlas A

    2015-01-01

    The use of cinnamon as a spice and flavouring agent is widespread throughout the world. Many different species of plants are commonly referred to as 'cinnamon'. 'True cinnamon' refers to the dried inner bark of Cinnamomum verum J. S. Presl (syn. C. zeylanicum) (Lauraceae). Other 'cinnamon' species, C. cassia (Nees & T. Nees) J. Presl (syn. C. aromaticum Nees) (Chinese cassia), C. loureiroi Nees (Saigon cassia), and C. burmannii (Nees & T. Nees) Blume (Indonesian cassia), commonly known as cassia, are also marketed as cinnamon. Since there is a prevalence of these various types of 'cinnamons' on the market, there is a need to develop a rapid technique that can readily differentiate between true cinnamon (C. verum) and other commonly marketed species. In the present study, coumarin and other marker compounds indicative of 'cinnamon' were analysed using DART-QToF-MS in various samples of cinnamon. This method involved the use of [M + H](+) ions in positive mode in addition to principal component analysis (PCA) using Mass Profiler Professional software to visualise several samples for quality and to discriminate 'true cinnamon' from other Cinnamomum species using the accurate mass capabilities of QToF-MS.

  1. Relations between emotion and conscious recollection of true and false autobiographical memories: an investigation using lorazepam as a pharmacological tool.

    Science.gov (United States)

    Pernot-Marino, Elodie; Danion, Jean-Marie; Hedelin, Guy

    2004-08-01

    Conscious recollection for autobiographical memory is the subjective experience of reliving a personal event mentally. Its frequency is strongly influenced by the emotion experienced at the time of the event. We addressed the issue of whether conscious recollection for autobiographical memories is also influenced by the emotion experienced at the time of retrieval. We used lorazepam, a benzodiazepine, as a pharmacological tool to modulate this emotional experience. Autobiographical memories were recorded in eight healthy volunteers using a diary study methodology. Each day, four entries were made by each subject: two true events, one altered event and one false event. For each event, the subjects were asked to rate emotional variables at encoding and at retrieval. Two months later, there were two sessions of recognition tests during which the subjects received orally an acute administration of either lorazepam (0.038 mg/kg) or placebo using a cross-over design. Subjective states of awareness were assessed using the Remember/Know/Guess procedure. Compared to placebo, lorazepam increased levels of conscious recollection, as assessed by Remember responses, for both true and false memories and induced an overestimation of the personal significance and emotional intensity of past events. Structural equation modelling showed that this overestimation was causal in the increased frequency of conscious recollection. Our results provide experimental evidence that the frequency of conscious recollection for both true and false autobiographical memories is influenced by the emotion experienced at the time of retrieval.

  2. The effects of interaction with the device described by procedural text on recall, true/false, and task performance.

    Science.gov (United States)

    Diehl, V A; Mills, C B

    1995-11-01

    In two experiments, subjects interacted to different extents with relevant devices while reading two complex multistep procedural texts and were then tested with task performance time, true/false, and recall measures. While reading, subjects performed the task (read and do), saw the experimenter perform the task (read and see experimenter do), imagined doing the task (read and imagine), looked at the device while reading (read and see), or only read (read only). Van Dijk and Kintsch's (1983) text representation theory led to the prediction that exposure to the task device (in the read-and-do, read-and-see, and read-and-see-experimenter-do conditions) would lead to the development of a stronger situation model and therefore faster task performance, whereas the read-only and read-and-see conditions would lead to a better textbase, and therefore better performance on the true/false and recall tasks. Paivio's (1991) dual coding theory led to the opposite prediction for recall. The results supported the text representation theory with task performance and recall. The read-and-see condition produced consistently good performance on the true/false measure. Amount of text study time contributed to recall performance. These findings support the notion that information available while reading leads to differential development of representations in memory, which, in turn, causes differences in performance on various measures.

  3. IMPORTANCE AND VULNERABILITY OF TRUE AND FAIR VIEW IN THE ROMANIAN ACCOUNTING ENVIRONMENT – CASE STUDY

    Directory of Open Access Journals (Sweden)

    Matis Dumitru

    2012-07-01

    Full Text Available This empirical study comprises items related to the operationalization of the concept True and Fair View in day to day accounting issues in Romanian accounting environment, demarche based on which we were interested in assessing the vulnerability of the concept and also the importance attributed by Romanian practitioners. If the vulnerability is high and the importance attributed low, the concept True and Fair View `s importance as an overall basis of accounting is limited, fact that will affect the quality of accounting information. The categories approached were chosen based on their implication related to the operationalization of the concept. The company’s financial directors are responsible for ensuring that the financial statements give True and Fair View and in the same manner the expert accountants must consider it important in order to prepare the financial statements in accordance to its requirements and finally the financial auditors must assess its existence, otherwise if this principle is neglected the companies would consequently present spurious results of their activity. All the categories above asserted that the concept doesn’t have only a symbolic role at the national level and their implication in achieving its requirements can be characterized by a proactive attitude. When it comes to assessing the potential vulnerability of TFV, our respondents agreed that items like legislative ambiguity and accounting estimates have the potential to affect TFV construct in the practical side of accounting.

  4. Husserl’s phenomenology in front of the problem of the understanding of the true man

    Directory of Open Access Journals (Sweden)

    Mestre Sidoncha, Urbano

    2009-04-01

    Full Text Available Taking from the very beginning the question “what is men?” as theoretical basis, our major concern in the present work was to demonstrate that the epistemic gap, which is traditionally opposed to naturalistic models of mind, is not yet everything there is to know when it comes to explain the reasons for our disagreement regarding such models. If we are right, the key criterion that will show how much reductive materialism is unsustainable as a solution for the mind/body problem, is not a dispute in the epistemic domain, but, rather, a criterion that we could entitle as “the comprehension of human”, that is, the particular way we feel as a human. In fact, one must ask if the conception we make of ourselves as such human beings (or as a true men, to evoke the most famous expression of Descartes can be included in the straightforward presentation of a vast assembly of organs. Furthermore, from an understanding of men as such an organic and material thing (a “pack of neurons”, as Francis Crick suggested, one can establish the idea of a Corporeal I (a Körper, according to the terminology of Husserl’s Ideen II, but that’s precisely the one which rules out the possibility on some kind of inner experience, that is, of an “auto-perception” or “inner-perception”: it will be, at the end, a body, but not consciousness of having such body, given that to consider this very last possibility of inner-perception requires the reintroduction of the difference – and therefore, of the relation – between minds and bodies, quite that particular distinction that was neglected by the reductive materialism as the only approach capable of circumvent the dualistic thesis for the mind-body relation.Tomando, desde el principio, la pregunta “¿qué es el hombre?” como indispensable base teorética, nuestra intención en este trabajo ha sido esencialmente demostrar que el hiato de carácter explicativo que tradicionalmente se le achaca a los

  5. Double impact of sterilizing pathogens: added value of increased life expectancy on pest control effectiveness.

    Science.gov (United States)

    Berec, Luděk; Maxin, Daniel

    2012-06-01

    Sterilizing pathogens are commonly assumed not to affect longevity of infected individuals, and if they do then negatively. Examples abound, however, of species in which the absence of reproduction actually increases life expectancy. This happens because by decreasing the energy outlay on reproduction individuals with lowered reproduction can live longer. Alternatively, fertile individuals are more susceptible to predators or parasitoids if the latter can capitalize on mating signals of the former. Here we develop and analyze an SI epidemiological model to explore whether and to what extent does such a life expectancy prolongation due to sterilizing pathogens affect host dynamics. In particular, we are interested in an added value of increased life expectancy on the possibility of successful pest control, that is, the effect of increased lifespan and hence increased potential of the infected individuals to spread the disease on pest control effectiveness. We show that although the parameter range in which we observe an effect of increased lifespan of the sterilized individuals is not large, the effect itself can be significant. In particular, the increase in pest control effectiveness can be very dramatic when disease transmission efficiency is close to birth rate, mortality rate of susceptibles is relatively high (i.e., the species is relatively short-lived), and sterilization efficiency is relatively high. Our results thus characterize pathogens that are promising candidates for an effective pest control and that might possibly be engineered if not occurring naturally.

  6. Single Audit: Single Audit Act Effectiveness Issues

    National Research Council Canada - National Science Library

    Thompson, Sally

    2002-01-01

    As discussed in the report we are releasing today, our work to review agency actions to ensure that recipients take timely and appropriate corrective actions to fix audit findings contained in single...

  7. New algorithm to determine true colocalization in combination with image restoration and time-lapse confocal microscopy to MAP kinases in mitochondria.

    Directory of Open Access Journals (Sweden)

    Jorge Ignacio Villalta

    Full Text Available The subcellular localization and physiological functions of biomolecules are closely related and thus it is crucial to precisely determine the distribution of different molecules inside the intracellular structures. This is frequently accomplished by fluorescence microscopy with well-characterized markers and posterior evaluation of the signal colocalization. Rigorous study of colocalization requires statistical analysis of the data, albeit yet no single technique has been established as a standard method. Indeed, the few methods currently available are only accurate in images with particular characteristics. Here, we introduce a new algorithm to automatically obtain the true colocalization between images that is suitable for a wide variety of biological situations. To proceed, the algorithm contemplates the individual contribution of each pixel's fluorescence intensity in a pair of images to the overall Pearsońs correlation and Manders' overlap coefficients. The accuracy and reliability of the algorithm was validated on both simulated and real images that reflected the characteristics of a range of biological samples. We used this algorithm in combination with image restoration by deconvolution and time-lapse confocal microscopy to address the localization of MEK1 in the mitochondria of different cell lines. Appraising the previously described behavior of Akt1 corroborated the reliability of the combined use of these techniques. Together, the present work provides a novel statistical approach to accurately and reliably determine the colocalization in a variety of biological images.

  8. Minimal-post-processing 320-Gbps true random bit generation using physical white chaos.

    Science.gov (United States)

    Wang, Anbang; Wang, Longsheng; Li, Pu; Wang, Yuncai

    2017-02-20

    Chaotic external-cavity semiconductor laser (ECL) is a promising entropy source for generation of high-speed physical random bits or digital keys. The rate and randomness is unfortunately limited by laser relaxation oscillation and external-cavity resonance, and is usually improved by complicated post processing. Here, we propose using a physical broadband white chaos generated by optical heterodyning of two ECLs as entropy source to construct high-speed random bit generation (RBG) with minimal post processing. The optical heterodyne chaos not only has a white spectrum without signature of relaxation oscillation and external-cavity resonance but also has a symmetric amplitude distribution. Thus, after quantization with a multi-bit analog-digital-convertor (ADC), random bits can be obtained by extracting several least significant bits (LSBs) without any other processing. In experiments, a white chaos with a 3-dB bandwidth of 16.7 GHz is generated. Its entropy rate is estimated as 16 Gbps by single-bit quantization which means a spectrum efficiency of 96%. With quantization using an 8-bit ADC, 320-Gbps physical RBG is achieved by directly extracting 4 LSBs at 80-GHz sampling rate.

  9. Earthworm Lumbricus rubellus MT-2: Metal Binding and Protein Folding of a True Cadmium-MT

    Directory of Open Access Journals (Sweden)

    Gregory R. Kowald

    2016-01-01

    Full Text Available Earthworms express, as most animals, metallothioneins (MTs—small, cysteine-rich proteins that bind d10 metal ions (Zn(II, Cd(II, or Cu(I in clusters. Three MT homologues are known for Lumbricus rubellus, the common red earthworm, one of which, wMT-2, is strongly induced by exposure of worms to cadmium. This study concerns composition, metal binding affinity and metal-dependent protein folding of wMT-2 expressed recombinantly and purified in the presence of Cd(II and Zn(II. Crucially, whilst a single Cd7wMT-2 species was isolated from wMT-2-expressing E. coli cultures supplemented with Cd(II, expressions in the presence of Zn(II yielded mixtures. The average affinities of wMT-2 determined for either Cd(II or Zn(II are both within normal ranges for MTs; hence, differential behaviour cannot be explained on the basis of overall affinity. Therefore, the protein folding properties of Cd- and Zn-wMT-2 were compared by 1H NMR spectroscopy. This comparison revealed that the protein fold is better defined in the presence of cadmium than in the presence of zinc. These differences in folding and dynamics may be at the root of the differential behaviour of the cadmium- and zinc-bound protein in vitro, and may ultimately also help in distinguishing zinc and cadmium in the earthworm in vivo.

  10. 'Cardiogenic vertigo'--true vertigo as the presenting manifestation of primary cardiac disease.

    Science.gov (United States)

    Newman-Toker, David E; Camargo, Carlos A

    2006-03-01

    A 90-year-old woman presented to a hospital emergency department with a brief loss of consciousness that was heralded by spinning vertigo lasting approximately 2 min. She had a long history of intermittent brief episodes of rotatory vertigo, presyncope, and non-vertiginous dizziness, occurring either with or without loss of consciousness. Although initially attributed to symptomatic carotid artery stenosis, these episodes persisted, despite surgical restoration of carotid artery blood flow 1 year after her first syncope. Her medical history was otherwise notable for hypertension, mild depression and a gradual decline in gait and balance function attributed to left hip arthritis and older age. Bedside history and examination, non-contrast head CT scan, electrocardiogram, transthoracic echocardiogram, and bedside cardiac telemetry. Sick sinus syndrome or severe reflex bradycardia with asystole causing recurrent, episodic vertigo, presyncope, non-vertiginous dizziness and syncope (Stokes-Adams attacks). Placement of a temporary pacing wire, followed by surgical implantation of a single-chamber ventricular (VVI) pacemaker.

  11. The European Banking Union: Will It Be a True Union without Risk Sharing?

    Directory of Open Access Journals (Sweden)

    Mario Sarcinelli

    2013-06-01

    Full Text Available The recent developments of the Euro crisis reveal the lack of clear or coherent thinking on the part of both the Eurozone finance ministers and the European Commission. The crisis in Cyprus is partly the consequence of decisions made on private sector involvement in the previous Greek bailout, and other such examples may be made. It is time, therefore, to look reality in the face and strengthen the structures of the EMU. The article is devoted to what has been done and what must still be done to make the European banking system more robust and less permeable to crises, and to preserve the single financial market. It looks at the initiatives of both the European Commission and the European Council to complete the EMU by creating a banking union, the doubts on the wisdom of entrusting banking oversight to the ECB, the organization of the ECB’s new tasks, the continuing absence of facilities for the recovery or liquidation of banks, as well as for a Euro-wide deposit insurance, the need for some form of risk-sharing in order to stabilise the economy, and thus the recourse to a common budget and the possibility of joint debt for the Eurozone.

  12. Estimating true human and animal host source contribution in quantitative microbial source tracking using the Monte Carlo method.

    Science.gov (United States)

    Wang, Dan; Silkie, Sarah S; Nelson, Kara L; Wuertz, Stefan

    2010-09-01

    Cultivation- and library-independent, quantitative PCR-based methods have become the method of choice in microbial source tracking. However, these qPCR assays are not 100% specific and sensitive for the target sequence in their respective hosts' genome. The factors that can lead to false positive and false negative information in qPCR results are well defined. It is highly desirable to have a way of removing such false information to estimate the true concentration of host-specific genetic markers and help guide the interpretation of environmental monitoring studies. Here we propose a statistical model based on the Law of Total Probability to predict the true concentration of these markers. The distributions of the probabilities of obtaining false information are estimated from representative fecal samples of known origin. Measurement error is derived from the sample precision error of replicated qPCR reactions. Then, the Monte Carlo method is applied to sample from these distributions of probabilities and measurement error. The set of equations given by the Law of Total Probability allows one to calculate the distribution of true concentrations, from which their expected value, confidence interval and other statistical characteristics can be easily evaluated. The output distributions of predicted true concentrations can then be used as input to watershed-wide total maximum daily load determinations, quantitative microbial risk assessment and other environmental models. This model was validated by both statistical simulations and real world samples. It was able to correct the intrinsic false information associated with qPCR assays and output the distribution of true concentrations of Bacteroidales for each animal host group. Model performance was strongly affected by the precision error. It could perform reliably and precisely when the standard deviation of the precision error was small (≤ 0.1). Further improvement on the precision of sample processing and q

  13. Cosmetic appreciation of lateralization of peripheral facial palsy: 'preference for left or right, true or mirror image?'.

    Science.gov (United States)

    Pouwels, Sjaak; Ingels, Koen; van Heerbeek, Niels; Beurskens, Carien

    2014-09-01

    There have been several studies in the past depicting asymmetry in 'normal' human faces. Evidence supports the fact that the right hemisphere is superior in the recognition of emotions expressed by the human face and indicates a right hemispheric specialization for processing emotional information. The primary aim of this study is to determine whether there is a difference in cosmetic appreciation of a left peripheral facial palsy compared to a right peripheral facial palsy? Pictures of patients with a facial palsy with House-Brackmann II-VI were reversed as a mirror image and offered as a pair of pictures, together with the true image. Forty-two patients and 24 medical professionals familiar with facial palsy were asked to choose the most attractive photograph. The primary 'end' point was the most attractive side in the pictures chosen by medical professionals and patients. The secondary 'end' points consisted of the preferences for the mirror or true image, and influences of the House-Brackmann score and age. Medical professionals preferred the photographs from patients with a right and left peripheral facial palsy (PFP) in, respectively, a mean of 44 % (41-48 %) and 56 % (52-59 %) of the pictures (p = 0.02). When comparing mirror and true image, patients with a left-sided facial palsy chose their mirror and true image as most attractive in 90 and 10 %, respectively (p 0.05). Subanalysis of patients with a PFP House-Brackmann score V and VI showed that medical professionals did not have a significant preference for a left nor right-sided facial palsy. Patients with a left-sided facial palsy chose their mirror image in all cases and patients with a right-sided palsy chose their mirror and true image in resp. 33 and 67 %. The House-Brackmann score (p = 0.52) and age (p = 0.73) of the patients did not influence preferences. This study, demonstrating that medical professionals find a right-sided facial palsy cosmetically less attractive than a left-sided, has

  14. Diagnostic evaluation of chronic inflammatory intestinal diseases in children and adolescents: MRI with true-FISP as new gold standard?

    International Nuclear Information System (INIS)

    Hohl, C.; Haage, P.; Krombach, G.A.; Schmidt, T.; Guenther, R.W.; Staatz, G.; Ahaus, M.

    2005-01-01

    Purpose: to evaluate the impact of magnetic resonance imaging (MRI) with use of True-FISP sequences in the evaluation of inflammatory bowel-wall changes in children and adolescents with Crohn's disease. Furthermore, the diagnostic procedure in children and adolescents with chronic inflammatory bowel disease (IBD) will be discussed in light of the relevant literature. Material and methods: twenty-four children and adolescents aged between 7 and 21 years with suspected or known IBD underwent MRI on a 1.5T-scanner (Philips ACS-NT, Best, Netherlands). One hour after 11 of a 2.5% mannitol solution was given orally, MR imaging was performed using coronal HASTE-M2D, coronal fat-suppressed T2-TSE, axial dynamic T1-weighted GE-sequences before and after i.v.-contrast material injection (0.1 mmol/kg Gd-DTPA) and using a 2D-balanced-FFE-sequence (True-FISP) before and after i.v.-contrast material injection in coronal and axial planes. The MR-images were correlated with endoscopy and the clinical findings. In 14 patients, a recently performed conventional radiographic enteroclysis was available. Each performed MRI sequence was evaluated by three experienced radiologists regarding the sensitivity and specificity of each sequence in the detection of inflammatory bowel wall changes. In addition, the image quality was assessed regarding the different tissue contrasts and the susceptibility to artifacts. The distension of the bowel wall and the patients' acceptance of the MRI examination were recorded. Results: with a sensitivity in detecting inflammatory small bowel changes of 93.3% (axial pre-contrast, coronal post-contrast) and 100% (axial post-contrast, coronal pre-contrast), the True-FISP outnumbers the other performed sequences (T1 = 80%, HASTE = 13.3% and T2-TSE = 53.3%). The difference between True-FISP and contrast-enhanced T1 was not statistically significant, whereas the difference between True-FISP and HASTE and T2-TSE, respectively. (orig.)

  15. TU-AB-BRC-05: Creation of a Monte Carlo TrueBeam Model by Reproducing Varian Phase Space Data

    International Nuclear Information System (INIS)

    O’Grady, K; Davis, S; Seuntjens, J

    2016-01-01

    Purpose: To create a Varian TrueBeam 6 MV FFF Monte Carlo model using BEAMnrc/EGSnrc that accurately reproduces the Varian representative dataset, followed by tuning the model’s source parameters to accurately reproduce in-house measurements. Methods: A BEAMnrc TrueBeam model for 6 MV FFF has been created by modifying a validated 6 MV Varian CL21EX model. Geometric dimensions and materials were adjusted in a trial and error approach to match the fluence and spectra of TrueBeam phase spaces output by the Varian VirtuaLinac. Once the model’s phase space matched Varian’s counterpart using the default source parameters, it was validated to match 10 × 10 cm"2 Varian representative data obtained with the IBA CC13. The source parameters were then tuned to match in-house 5 × 5 cm"2 PTW microDiamond measurements. All dose to water simulations included detector models to include the effects of volume averaging and the non-water equivalence of the chamber materials, allowing for more accurate source parameter selection. Results: The Varian phase space spectra and fluence were matched with excellent agreement. The in-house model’s PDD agreement with CC13 TrueBeam representative data was within 0.9% local percent difference beyond the first 3 mm. Profile agreement at 10 cm depth was within 0.9% local percent difference and 1.3 mm distance-to-agreement in the central axis and penumbra regions, respectively. Once the source parameters were tuned, PDD agreement with microDiamond measurements was within 0.9% local percent difference beyond 2 mm. The microDiamond profile agreement at 10 cm depth was within 0.6% local percent difference and 0.4 mm distance-to-agreement in the central axis and penumbra regions, respectively. Conclusion: An accurate in-house Monte Carlo model of the Varian TrueBeam was achieved independently of the Varian phase space solution and was tuned to in-house measurements. KO acknowledges partial support by the CREATE Medical Physics Research

  16. Single-Sex Classrooms

    Science.gov (United States)

    Protheroe, Nancy

    2009-01-01

    Although single-sex education was once the norm in the U.S., the practice has largely been confined to private schools for more than a century. However, with the introduction of the final version of the U.S. Department of Education's so-called single-sex regulations in 2006, public schools were allowed greater flexibility to offer single-sex…

  17. Superconducting Single Photon Detectors

    NARCIS (Netherlands)

    Dorenbos, S.N.

    2011-01-01

    This thesis is about the development of a detector for single photons, particles of light. New techniques are being developed that require high performance single photon detection, such as quantum cryptography, single molecule detection, optical radar, ballistic imaging, circuit testing and

  18. Single frequency intracavity SRO

    DEFF Research Database (Denmark)

    Abitan, Haim; Buchhave, Preben

    2000-01-01

    Summary form only given. A single resonance optical parametric oscillator (SRO) is inserted intracavity to a CW high power, single frequency, and ring Nd:YVO4 laser. We obtain a stable single frequency CW SRO with output at 1.7-1.9 μm (idler) and a resonating signal at 2.3-2.6 μm. The behavior...

  19. Single atom oscillations

    International Nuclear Information System (INIS)

    Wiorkowski, P.; Walther, H.

    1990-01-01

    Modern methods of laser spectroscopy allow the study of single atoms or ions in an unperturbed environment. This has opened up interesting new experiments, among them the detailed study of radiation-atom coupling. In this paper, the following two experiments dealing with this problem are reviewed: the single-atom maser and the study of the resonance fluorescence of a single stored ion. The simplest and most fundamental system for studying radiation-matter coupling is a single two-level atom interacting with a single mode of an electromagnetic field in a cavity. This problem received a great deal of attention shortly after the maser was invented

  20. EFFECTIVENESS EVALUATION OF TOOTHPASTE BASED ON THE CEDAR ESSENTIAL OIL FOR PREVENTING TRUE ORAL PATHOLOGIC HALITOSIS

    Directory of Open Access Journals (Sweden)

    S. B. Ulitovsky

    2017-01-01

    Full Text Available Introduction. Given the mechanism of the development of halitosis and low efficiency of its self-elimination, means of oral hygiene with antiglycation characteristics should efficiently remove plaque and slow its formation, have antiseptic, antimicrobial and anti-inflammatory properties; have high deodorant quality, strengthen natural defense mechanisms and be safe to oral tissues and organism as a whole. Toothpastes and mouthwashes should consist of components that are able to mask and as well detoxify volatile sulphur and nitrogencontaining compounds produced by microorganisms of the oral cavity. The objective is to evaluate the dynamics of deodorant effect of the means of oral hygiene for identifying the effectiveness of preventive measures among the population.Materials and methods. At the department of preventive dentistry of the Federal State Budgetary Educational Institution of Higher Education «Pavlov First Saint Petersburg State Medical University” of the Ministry of Healthcare of the Russian Federation, we conducted the diagnostic assessment of halitosis based on the method of index determination of the deodorant effect by Ulitovsky S. B. This method allows to monitor the deodorant effect and in a single definition to determine the level of mouth breathing before using the means of hygiene.Results. The research revealed that the indicators of index determination of the deodorant effect by Ulitovsky S. B to the end of the study was 44.78±1.73 % in the 1st group and 26.92±1.61 % in the control group. Based on these data, which depended on the degree of antimicrobial activity of personal means of oral hygiene, the examined sample of prophylactic toothpaste showed the significant activity for such test cultures as Ps. aeruginosa, B. cereus and C. albicans.Conclusions. Based on the evaluating the dynamics of the deodorant effect of the means of oral hygiene throughout the study we identified the increasing of deodorant effect according