WorldWideScience

Sample records for single synchrotron pulse

  1. Pulse picker for synchrotron radiation driven by a surface acoustic wave.

    Science.gov (United States)

    Vadilonga, Simone; Zizak, Ivo; Roshchupkin, Dmitry; Petsiuk, Andrei; Dolbnya, Igor; Sawhney, Kawal; Erko, Alexei

    2017-05-15

    A functional test for a pulse picker for synchrotron radiation was performed at Diamond Light Source. The purpose of a pulse picker is to select which pulse from the synchrotron hybrid-mode bunch pattern reaches the experiment. In the present work, the Bragg reflection on a Si/B4C multilayer was modified using surface acoustic wave (SAW) trains. Diffraction on the SAW alters the direction of the x rays and it can be used to modulate the intensity of the x rays that reach the experimental chamber. Using electronic modulation of the SAW amplitude, it is possible to obtain different scattering conditions for different x-ray pulses. To isolate the single bunch, the state of the SAW must be changed in the short time gap between the pulses. To achieve the necessary time resolution, the measurements have been performed in conical diffraction geometry. The achieved time resolution was 120 ns.

  2. Chemical crystallography with pulsed neutrons and synchrotron x-rays

    International Nuclear Information System (INIS)

    Carrondo, M.A.; Jeffrey, G.A.

    1988-01-01

    Solid-state chemists and physicists, crystallographers and molecular biologists who are using or who plan to use the special properties of pulsed neutron spallation and synchrotron X-ray sources will find this book invaluable. Those scientists who have not yet gained experience in working with such sources will find the basic physics of the radiations, their production and their scattering properties explained, together with descriptions of the different types of diffraction experiments which use them

  3. A Single-Pulse Integrator

    DEFF Research Database (Denmark)

    Miller, Arne

    1974-01-01

    A single-pulse integrator is described. It gives a relative measure of the integral of the output signal from a coil monitor on the Risø 10 MeV linear accelerator, and displays the value on a digital voltmeter. The reproduccibility is found to be better than ±1% for an accelerated pulse charge...

  4. Kharkov 3-GeV pulse stretcher ring as a source of synchrotron radiation

    International Nuclear Information System (INIS)

    Boldyshev, V.F.; Gladkikh, P.I.; Grigor'ev, Y.N.; Guk, I.S.; Efimov, S.V.; Karnaukhov, I.M.; Kononenko, S.G.; Mocheshnikov, N.I.; Popkov, Y.P.; Tarasenko, A.S.; Telegin, Y.N.; Chechetenko, V.F.; Shcherbakov, A.A.; Titov, V.A.; Nagaenko, M.G.

    1989-01-01

    The article discusses the possibility of using the pulse stretcher ring, designed at the Kharkov Institute of Physics and Technology, as a synchrotron radiation source (SRS). Comparison is made between our SRS design parameters and those of other dedicated SRSs

  5. Preliminary studies of the quickly pulsed synchrotron involved in the Beta-Beam project; Etudes preliminaires du synchrotron rapidement pulse du projet Beta-Beam

    Energy Technology Data Exchange (ETDEWEB)

    Lachaize, A

    2007-07-01

    This study presents a quickly-pulsed synchrotron able to accelerate He{sup 6} and Ne{sup 18} beams from 100 MeV/u till 3.5 GeV (proton equivalent) The accelerator is made up of 48 bending dipoles and 42 focusing quadrupoles. The design of the HF accelerating system, the bunch injection and the correction of errors in beam dynamics are dealt with.

  6. Single bunch transfer system for the National Synchrotron Light Source

    International Nuclear Information System (INIS)

    Sheehan, J.; Singh, O.; Rambo, W.

    1983-01-01

    The accelerator system at the National Synchrotron Light Source consists of an S-band 85 MeV linac and three synchrotron rings. The electron beam from the linac is accelerated by the booster ring to 600 MeV and transferred to one of the two storage rings. The smaller of the two rings operates between 300 and 800 MeV emtting photons in the vacuum ultraviolet (VUV), while the larger storage ring operates up to 2.5 GeV and emits photons in the x-ray spectrum. A system is described for loading the storage rings by filling a single-phase space bunch in the booster ring and transferring it at the end of each booster cycle into a selected bucket in one of the storage rings. By controlling the timing of the transfer on successive transfer cycles, many fill patterns may be obtained

  7. Controlled generation of a single Trichel pulse and a series of single Trichel pulses in air

    Science.gov (United States)

    Mizeraczyk, Jerzy; Berendt, Artur; Akishev, Yuri

    2018-04-01

    In this paper, a simple method for the controlled generation of a single Trichel pulse or a series of single Trichel pulses of a regulated repetition frequency in air is proposed. The concept of triggering a single Trichel pulse or a series of such pulses is based on the precise controlling the voltage inception of the negative corona, which can be accomplished through the use of a ramp voltage pulse or a series of such pulses with properly chosen ramp voltage pulse parameters (rise and fall times, and ramp voltage pulse repetition frequency). The proposal has been tested in experiments using a needle-to-plate electrode arrangement in air, and reproducible Trichel pulses (single or in a series) were obtained by triggering them with an appropriately designed voltage waveform. The proposed method and results obtained have been qualitatively analysed. The analysis provides guidance for designing the voltage ramp pulse in respect of the generation of a single Trichel pulse or a series of single Trichel pulses. The controlled generation of a single Trichel pulse or a series of such pulses would be a helpful research tool for the refined studies of the fundamental processes in a negative corona discharge in a single- (air is an example) and multi-phase gaseous fluids. The controlled generation of a single Trichel pulse or a series of Trichel pulses can also be attractive for those corona treatments which need manipulation of the electric charge and heat portions delivered by the Trichel pulses to the object.

  8. Intrinsic chirp of single-cycle pulses

    International Nuclear Information System (INIS)

    Lin Qiang; Zheng Jian; Dai Jianming; Ho, I-Chen; Zhang, X.-C.

    2010-01-01

    The Fourier transform-limited electromagnetic pulse has been regarded to be free of chirps for a long time. This is no longer true if the pulse duration goes down to or less than one optical cycle. We report the experimental observation of intrinsic chirps in such pulses with the sub-single-cycle terahertz (THz) waveforms obtained with a standard THz time-domain spectroscopy system. The results confirm the break down of the carrier-envelope (CE) expression for single-cycle optical pulses, and may influence the experimental measurements and theoretical modeling with single-cycle pulses.

  9. Intense, broadband, pulsed I-R source at the National Synchrotron Light Source

    International Nuclear Information System (INIS)

    Williams, G.P.

    1984-01-01

    We describe a broadband (1 μm to 1 mm) synchrotron radiation infrared source, pulsed each 20 to 180 nseconds and delivering about 10 15 photons/sec/1% bandpass into f10 optics. The source size is diffraction limited. This source is thus 100 to 1000 times brighter than a 2000 0 K black body, very stable and capable of being used for calibration

  10. The first pulse of the extremely bright GRB 130427A: a test lab for synchrotron shocks.

    Science.gov (United States)

    Preece, R; Burgess, J Michael; von Kienlin, A; Bhat, P N; Briggs, M S; Byrne, D; Chaplin, V; Cleveland, W; Collazzi, A C; Connaughton, V; Diekmann, A; Fitzpatrick, G; Foley, S; Gibby, M; Giles, M; Goldstein, A; Greiner, J; Gruber, D; Jenke, P; Kippen, R M; Kouveliotou, C; McBreen, S; Meegan, C; Paciesas, W S; Pelassa, V; Tierney, D; van der Horst, A J; Wilson-Hodge, C; Xiong, S; Younes, G; Yu, H-F; Ackermann, M; Ajello, M; Axelsson, M; Baldini, L; Barbiellini, G; Baring, M G; Bastieri, D; Bellazzini, R; Bissaldi, E; Bonamente, E; Bregeon, J; Brigida, M; Bruel, P; Buehler, R; Buson, S; Caliandro, G A; Cameron, R A; Caraveo, P A; Cecchi, C; Charles, E; Chekhtman, A; Chiang, J; Chiaro, G; Ciprini, S; Claus, R; Cohen-Tanugi, J; Cominsky, L R; Conrad, J; D'Ammando, F; de Angelis, A; de Palma, F; Dermer, C D; Desiante, R; Digel, S W; Di Venere, L; Drell, P S; Drlica-Wagner, A; Favuzzi, C; Franckowiak, A; Fukazawa, Y; Fusco, P; Gargano, F; Gehrels, N; Germani, S; Giglietto, N; Giordano, F; Giroletti, M; Godfrey, G; Granot, J; Grenier, I A; Guiriec, S; Hadasch, D; Hanabata, Y; Harding, A K; Hayashida, M; Iyyani, S; Jogler, T; Jóhannesson, G; Kawano, T; Knödlseder, J; Kocevski, D; Kuss, M; Lande, J; Larsson, J; Larsson, S; Latronico, L; Longo, F; Loparco, F; Lovellette, M N; Lubrano, P; Mayer, M; Mazziotta, M N; Michelson, P F; Mizuno, T; Monzani, M E; Moretti, E; Morselli, A; Murgia, S; Nemmen, R; Nuss, E; Nymark, T; Ohno, M; Ohsugi, T; Okumura, A; Omodei, N; Orienti, M; Paneque, D; Perkins, J S; Pesce-Rollins, M; Piron, F; Pivato, G; Porter, T A; Racusin, J L; Rainò, S; Rando, R; Razzano, M; Razzaque, S; Reimer, A; Reimer, O; Ritz, S; Roth, M; Ryde, F; Sartori, A; Scargle, J D; Schulz, A; Sgrò, C; Siskind, E J; Spandre, G; Spinelli, P; Suson, D J; Tajima, H; Takahashi, H; Thayer, J G; Thayer, J B; Tibaldo, L; Tinivella, M; Torres, D F; Tosti, G; Troja, E; Usher, T L; Vandenbroucke, J; Vasileiou, V; Vianello, G; Vitale, V; Werner, M; Winer, B L; Wood, K S; Zhu, S

    2014-01-03

    Gamma-ray burst (GRB) 130427A is one of the most energetic GRBs ever observed. The initial pulse up to 2.5 seconds is possibly the brightest well-isolated pulse observed to date. A fine time resolution spectral analysis shows power-law decays of the peak energy from the onset of the pulse, consistent with models of internal synchrotron shock pulses. However, a strongly correlated power-law behavior is observed between the luminosity and the spectral peak energy that is inconsistent with curvature effects arising in the relativistic outflow. It is difficult for any of the existing models to account for all of the observed spectral and temporal behaviors simultaneously.

  11. Generating picosecond x-ray pulses in synchrotron light sources using dipole kickers

    Directory of Open Access Journals (Sweden)

    W. Guo

    2007-02-01

    Full Text Available The duration of the x-ray pulse generated at a synchrotron light source is typically tens of picoseconds. Shorter pulses are highly desired by the users. In electron storage rings, the vertical beam size is usually orders of magnitude less than the bunch length due to radiation damping; therefore, a shorter pulse can be obtained by slitting the vertically tilted bunch. Zholents proposed tilting the bunch using rf deflection. We found that tilted bunches can also be generated by a dipole magnet kick. A vertical tilt is developed after the kick in the presence of nonzero chromaticity. The tilt was successfully observed and a 4.2-ps pulse was obtained from a 27-ps electron bunch at the Advanced Photon Source. Based on this principle, we propose a short-pulse generation scheme that produces picosecond x-ray pulses at a repetition rate of 1–2 kHz, which can be used for pump-probe experiments.

  12. A method for ultrashort electron pulse-shape measurement using coherent synchrotron radiation

    International Nuclear Information System (INIS)

    Geloni, G.; Yurkov, M.V.

    2003-03-01

    In this paper we discuss a method for nondestructive measurements of the longitudinal profile of sub-picosecond electron bunches for X-ray free electron lasers (XFELs). The method is based on the detection of the coherent synchrotron radiation (CSR) spectrum produced by a bunch passing a dipole magnet system. This work also contains a systematic treatment of synchrotron radiation theory which lies at the basis of CSR. Standard theory of synchrotron radiation uses several approximations whose applicability limits are often forgotten: here we present a systematic discussion about these assumptions. Properties of coherent synchrotron radiation from an electron moving along an arc of a circle are then derived and discussed. We describe also an effective and practical diagnostic technique based on the utilization of an electromagnetic undulator to record the energy of the coherent radiation pulse into the central cone. This measurement must be repeated many times with different undulator resonant frequencies in order to reconstruct the modulus of the bunch form-factor. The retrieval of the bunch profile function from these data is performed by means of deconvolution techniques: for the present work we take advantage of a constrained deconvolution method. We illustrate with numerical examples the potential of the proposed method for electron beam diagnostics at the TESLA test facility (TTF) accelerator. Here we choose, for emphasis, experiments aimed at the measure of the strongly non-Gaussian electron bunch profile in the TTF femtosecond-mode operation. We demonstrate that a tandem combination of a picosecond streak camera and a CSR spectrometer can be used to extract shape information from electron bunches with a narrow leading peak and a long tail. (orig.)

  13. Efficiency of respiratory-gated delivery of synchrotron-based pulsed proton irradiation

    International Nuclear Information System (INIS)

    Tsunashima, Yoshikazu; Vedam, Sastry; Dong, Lei; Bues, Martin; Balter, Peter; Smith, Alfred; Mohan, Radhe; Umezawa, Masumi; Sakae, Takeji

    2008-01-01

    Significant differences exist in respiratory-gated proton beam delivery with a synchrotron-based accelerator system when compared to photon therapy with a conventional linear accelerator. Delivery of protons with a synchrotron accelerator is governed by a magnet excitation cycle pattern. Optimal synchronization of the magnet excitation cycle pattern with the respiratory motion pattern is critical to the efficiency of respiratory-gated proton delivery. There has been little systematic analysis to optimize the accelerator's operational parameters to improve gated treatment efficiency. The goal of this study was to estimate the overall efficiency of respiratory-gated synchrotron-based proton irradiation through realistic simulation. Using 62 respiratory motion traces from 38 patients, we simulated respiratory gating for duty cycles of 30%, 20% and 10% around peak exhalation for various fixed and variable magnet excitation patterns. In each case, the time required to deliver 100 monitor units in both non-gated and gated irradiation scenarios was determined. Based on results from this study, the minimum time required to deliver 100 MU was 1.1 min for non-gated irradiation. For respiratory-gated delivery at a 30% duty cycle around peak exhalation, corresponding average delivery times were typically three times longer with a fixed magnet excitation cycle pattern. However, when a variable excitation cycle was allowed in synchrony with the patient's respiratory cycle, the treatment time only doubled. Thus, respiratory-gated delivery of synchrotron-based pulsed proton irradiation is feasible and more efficient when a variable magnet excitation cycle pattern is used

  14. High-speed nuclear quality pulse height analyzer for synchrotron-based applications

    International Nuclear Information System (INIS)

    Beche, Jean-Francois; Bucher, Jerome J.; Fabris, Lorenzo; Riot, Vincent J.

    2001-01-01

    A high throughput Pulse Height Analyzer system for synchrotron-based applications requiring high resolution, high processing speed and low dead time has been developed. The system is comprised of a 120ns 12-bit nuclear quality Analog to Digital converter with a self-adaptive fast peak detector-stretcher and a custom-made fast histogramming memory module that records and processes the digitized data. The histogramming module is packaged in a VME or VXI compatible interface. Data is transferred through a fast optical link from the memory interface to a computer. A dedicated data acquisition program matches the hardware characteristics of the histogramming memory module. The data acquisition system allows for two data collection modes: ''standard'' data acquisition mode where the data is accumulated and read in synchronization with an external trigger and ''live'' data acquisition mode where the system operates as a standard Pulse Height Analyzer. The acquisition, standard or live, can be performed on several channels simultaneously. A two-channel prototype has been demonstrated at the Stanford Synchrotron Radiation Laboratory accelerator in conjunction with an X-ray Fluorescence Absorption Spectroscopy experiment. A detailed description of the entire system is given and experimental data is shown

  15. NATO Advanced Study Institute on Chemical Crystallography with Pulsed Neutrons and Synchrotron X-Rays

    CERN Document Server

    Jeffrey, George

    1988-01-01

    X-ray and neutron crystallography have played an increasingly impor­ tant role in the chemical and biochemical sciences over the past fifty years. The principal obstacles in this methodology, the phase problem and com­ puting, have been overcome. The former by the methods developed in the 1960's and just recognised by the 1985 Chemistry Nobel Prize award to Karle and Hauptman, the latter by the dramatic advances that have taken place in computer technology in the past twenty years. Within the last decade, two new radiation sources have been added to the crystallographer's tools. One is synchrotron X-rays and the other is spallation neutrons. Both have much more powerful fluxes than the pre­ vious sources and they are pulsed rather than continuos. New techniques are necessary to fully exploit the intense continuos radiation spectrum and its pulsed property. Both radiations are only available from particular National Laboratories on a guest-user basis for scientists outside these Na­ tional Laboratories. Hi...

  16. Preliminary tests of a second harmonic rf system for the intense pulsed neutron source synchrotron

    International Nuclear Information System (INIS)

    Norem, J.; Brandeberry, F.

    1983-01-01

    The Rapid Cycling Synchrotron (RCS) of the Intense Pulsed Neutron Source (IPNS) operating at Argonne National Laboratory is presently producing intensities of 2 to 2.5 x 10 12 protons per pulse (ppp) with the addition of a new ion source. This intensity is close to the space charge limit of the machine, estimated at approx. 3 x 10 12 ppp, depending somewhat on the available aperture. Accelerator improvements are being directed at (1) increasing beam intensities for neutron science, (2) lowering acceleration losses to minimize activation, and (3) gaining better control of the beam so that losses can be made to occur when and where they can be most easily controlled. We are now proposing a third cavity for the RF system which would provide control of the longitudinal bunch shape during the cycle which would permit raising the effective space charge limit of the accelerator and reducing losses by providing more RF voltage at maximum acceleration. This paper presents an outline of the expected benefits together with recent results obtained during low energy operation with one of the two existing cavities operating at the second harmonic

  17. Proposed second harmonic acceleration system for the intense pulsed neutron source rapid cycling synchrotron

    International Nuclear Information System (INIS)

    Norem, J.; Brandeberry, F.; Rauchas, A.

    1983-01-01

    The Rapid Cycling Synchrotron (RCS) of the Intense Pulsed Neutron Source (IPNS) operating at Argonne National Laboratory is presently producing intensities of 2 to 2.5 x 10 12 protons per pulse (ppp) with the addition of a new ion source. This intensity is close to the space charge limit of the machine, estimated at approx.3 x 10 12 ppp, depending somewhat on the available aperture. With the present good performance in mind, accelerator improvements are being directed at: (1) increasing beam intensities for neutron science; (2) lowering acceleration losses to minimize activation; and (3) gaining better control of the beam so that losses can be made to occur when and where they can be most easily controlled. On the basis of preliminary measurements, we are now proposing a third cavity for the RF systems which would provide control of the longitudinal bunch shape during the cycle which would permit raising the effective space charge limit of the accelerator and reducing losses

  18. Application of CHESS single-bounce capillaries at synchrotron beamlines

    International Nuclear Information System (INIS)

    Huang, R; Szebenyi, T; Pfeifer, M; Woll, A; Smilgies, D-M; Finkelstein, K; Dale, D; Bilderback, D H; Wang, Y; J Vila-Comamala, J; Gillilan, R; Cook, M

    2014-01-01

    Single-bounce capillaries are achromatic X-ray focusing optics that can provide efficient and high demagnification focusing with large numerical apertures. Capillary fabrication at CHESS can be customized according to specific application requirements. Exemplary applications are reviewed in this paper, as well as recent progress on condensers for high-resolution transmission X-ray microscopy and small focal size capillaries.

  19. Gating circuit for single photon-counting fluorescence lifetime instruments using high repetition pulsed light sources

    International Nuclear Information System (INIS)

    Laws, W.R.; Potter, D.W.; Sutherland, J.C.

    1984-01-01

    We have constructed a circuit that permits conventional timing electronics to be used in single photon-counting fluorimeters with high repetition rate excitation sources (synchrotrons and mode-locked lasers). Most commercial time-to-amplitude and time-to-digital converters introduce errors when processing very short time intervals and when subjected to high-frequency signals. This circuit reduces the frequency of signals representing the pulsed light source (stops) to the rate of detected fluorescence events (starts). Precise timing between the start/stop pair is accomplished by using the second stop pulse after a start pulse. Important features of our design are that the circuit is insensitive to the simultaneous occurrence of start and stop signals and that the reduction in the stop frequency allows the start/stop time interval to be placed in linear regions of the response functions of commercial timing electronics

  20. Pulsed Single Frequency MOPA Laser, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Latest advances in semiconductor optoelectronics makes it possible to develop compact light weight robust sources of coherent optical pulses, demanded for numerous...

  1. Interaction of solitary pulses in single mode optical fibres | Usman ...

    African Journals Online (AJOL)

    Two solitary waves launched, by way of incidence, into an optical fibre from a single pulse if the pulses are in-phase as understood from results of inverse scattering transform method applied to the cubic nonlinear Schrödinger equations, (CNLSE\\'s). The single CNLSE is then understood to describe evolution of coupled ...

  2. Picosecond chirped pulse compression in single-mode fibers

    International Nuclear Information System (INIS)

    Wenhua Cao; Youwei Zhang

    1995-01-01

    In this paper, the nonlinear propagation of picosecond chirped pulses in single mode fibers has been investigated both analytically and numerically. Results show that downchirped pulses can be compressed owing to normal group-velocity dispersion. The compression ratio depends both on the initial peak power and on the initial frequency chirp of the input pulse. While the compression ratio depends both on the initial peak power and on the initial frequency chirp of the input pulse. While the compression ratio increases with the negative frequency chirp, it decreases with the initial peak power of the input pulse. This means that the self-phase modulation induced nonlinear frequency chirp which is linear and positive (up-chirp) over a large central region of the pulse and tends to cancel the initial negative chirp of the pulse. It is also shown that, as the negative chirped pulse compresses temporally, it synchronously experiences a spectral narrowing

  3. Single-pulse electrons from a linear accelerator

    International Nuclear Information System (INIS)

    Antoku, Shigetoshi; Sunayashiki, Tadashi; Takeoka, Seiji; Kato, Kazushi

    1976-01-01

    The electronic circuits of a 35 MeV linear accelerator at Hiroshima University were modified to produce single-pulse electrons. Single-pulse electrons were obtained by synchronizing one of eight pulses from an electron gun modulator, 120 pps, to one of the micro-waves from a klystron, 15 pps. After single-pulse electrons were discharged, a signal was relayed to a stop-gate circuit from a binary scaler which was connected to the gun modulator. Although reproducibility of single-pulse electrons and stability of electron output per pulse were not completely satisfactory, it was possible to use for radiobiological studies. Biological effects of single-pulse electrons (energy: 25 MeV, dose rate: 10 10 rad/min) on cultured mammalian cells and on mice were nearly equal to those of multi-pulse electrons (25 MeV, 10 7 rad/min) and Co-60 γ-rays (dose rate: 100 rad/min). (auth.)

  4. Single and Multi-Pulse Low-Energy Conical Theta Pinch Inductive Pulsed Plasma Thruster Performance

    Science.gov (United States)

    Hallock, A. K.; Martin, A. K.; Polzin, K. A.; Kimberlin, A. C.; Eskridge, R. H.

    2013-01-01

    Impulse bits produced by conical theta-pinch inductive pulsed plasma thrusters possessing cone angles of 20deg, 38deg, and 60deg, were quantified for 500J/pulse operation by direct measurement using a hanging-pendulum thrust stand. All three cone angles were tested in single-pulse mode, with the 38deg model producing the highest impulse bits at roughly 1 mN-s operating on both argon and xenon propellants. A capacitor charging system, assembled to support repetitively-pulsed thruster operation, permitted testing of the 38deg thruster at a repetition-rate of 5 Hz at power levels of 0.9, 1.6, and 2.5 kW. The average thrust measured during multiple-pulse operation exceeded the value obtained when the single-pulse impulse bit is multiplied by the repetition rate.

  5. Measurement of the single-shot pulse energy of a free electron laser using a cryogenic radiometer

    Energy Technology Data Exchange (ETDEWEB)

    Masahiro, Kato; Norio, Saito; Yuichiro, Morishita; Takahiro, Tanaka [National Institute of Advanced Industrial Science and Technology (AIST), NMIJ, Tsukuba (Japan); Masahiro, Kato; Norio, Saito; Kai, Tiedtke; Pavle N, Juranic; Sorokin, A.A.; Richter, M.; Takahiro, Tanaka; Mitsuru, Nagasono; Makina, Yabashi; Kensuke, Tono; Tadashi, Togashi; Tetsuya, Ishikawa [RIKEN, XFEL Project Head Office, Kouto, Sayo, Hyogo (Japan); Kai, Tiedtke; Pavle N, Juranic; Sorokin, A.A.; Jastrow, U. [Deutsches Elektronen-Synchrotron, DESY, Hamburg (Germany); Sorokin, A.A. [Ioffe Physico-Technical Institute, Polytekhnicheskaya 26, St Petersburg (Russian Federation); Richter, M.; Kroth, U.; Schoppe, H. [Physikalisch-Technische Bundesanstalt, PTB, Berlin (Germany); Tadashi, Togashi; Hiroaki, Kimura; Haruhiko, Ohashi [Japan Synchrotron Radiation Research Institute, Sayo, Hyogo (Japan)

    2010-10-15

    The absolute single-shot pulse energy of the SPring 8 extreme ultraviolet (EUV) free electron laser (FEL) was measured using a cryogenic radiometer with a relative standard uncertainty of 3%. The temperature change of the cavity in the cryogenic radiometer caused by an incident FEL pulse was determined using a lock-in amplifier and an ac Wheatstone bridge. The measured pulse energies were compared with a gas-monitor detector developed by Physikalisch-Technische Bundesanstalt/Deutsches Elektronen-Synchrotron/Ioffe Physico-Technical Institute (Ioffe) at a wavelength of 51.3 nm at the SPring-8 EUV-FEL in a shot-to-shot mode. The pulse energies measured using the two detectors agree within 2.0%. (authors)

  6. Focusing of white synchrotron radiation using large-acceptance cylindrical refractive lenses made of single – crystal diamond

    Energy Technology Data Exchange (ETDEWEB)

    Polikarpov, M., E-mail: polikarpov.maxim@mail.ru [Immanuel Kant Baltic Federal University, Nevskogo 14a, 23600 Kaliningrad (Russian Federation); Snigireva, I. [European Synchrotron Radiation Facility, 71 avenue des Martyrs, Grenoble 38043 (France); Snigirev, A. [Immanuel Kant Baltic Federal University, Nevskogo 14a, 23600 Kaliningrad (Russian Federation); European Synchrotron Radiation Facility, 71 avenue des Martyrs, Grenoble 38043 (France)

    2016-07-27

    Large-aperture cylindrical refractive lenses were manufactured by laser cutting of single-crystal diamond. Five linear single lenses with apertures of 1 mm and the depth of the structure of 1.2 mm were fabricated and tested at the ESRF ID06 beamline performing the focusing of white-beam synchrotron radiation. Uniform linear focus was stable during hours of exposure, representing such lenses as pre-focusing and collimating devices suitable for the front-end sections of today synchrotron radiation sources.

  7. Focusing of white synchrotron radiation using large-acceptance cylindrical refractive lenses made of single – crystal diamond

    International Nuclear Information System (INIS)

    Polikarpov, M.; Snigireva, I.; Snigirev, A.

    2016-01-01

    Large-aperture cylindrical refractive lenses were manufactured by laser cutting of single-crystal diamond. Five linear single lenses with apertures of 1 mm and the depth of the structure of 1.2 mm were fabricated and tested at the ESRF ID06 beamline performing the focusing of white-beam synchrotron radiation. Uniform linear focus was stable during hours of exposure, representing such lenses as pre-focusing and collimating devices suitable for the front-end sections of today synchrotron radiation sources.

  8. Ultrafast geometric control of a single qubit using chirped pulses

    International Nuclear Information System (INIS)

    Hawkins, Patrick E; Malinovskaya, Svetlana A; Malinovsky, Vladimir S

    2012-01-01

    We propose a control strategy to perform arbitrary unitary operations on a single qubit based solely on the geometrical phase that the qubit state acquires after cyclic evolution in the parameter space. The scheme uses ultrafast linearly chirped pulses and provides the possibility of reducing the duration of a single-qubit operation to a few picoseconds.

  9. Single-particle And Collective Effects Of Cubic Nonlinearity In The Beam Dynamics Of Proton Synchrotrons

    CERN Document Server

    Tran Hy, J

    1998-01-01

    This thesis describes some new studies of the effects of cubic nonlinearities arising from image-charge forces and octupole magnets on the transverse beam dynamics of proton synchrotrons and storage rings, and also a study of the damping of coherent oscillations using a feed-back damper. In the latter case, various corrective algorithms were modeled using linear one-turn maps. Kicks of fixed amplitude but appropriate sign were shown to provide linear damping and no coherent tune shift, though the rate predicted analytically was somewhat higher than that observed in simulations. This algorithm gave much faster damping (for equal power) than conventional proportional kicks, which damp exponentially. Two single-particle effects of the image-change force were investigated: distortion of the momentum dispersion function and amplitude dependence of the betatron tunes (resulting in tune spread). The former is calculated using transfer maps and the method of undetermined coefficients, the latter by solving the cubic ...

  10. Real-time Bacterial Detection by Single Cell Based Sensors UsingSynchrotron FTIR Spectromicroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Veiseh, Mandana; Veiseh, Omid; Martin, Michael C.; Bertozzi,Carolyn; Zhang, Miqin

    2005-08-10

    Microarrays of single macrophage cell based sensors weredeveloped and demonstrated for real time bacterium detection bysynchrotron FTIR microscopy. The cells were patterned on gold-SiO2substrates via a surface engineering technique by which the goldelectrodes were immobilized with fibronectin to mediate cell adhesion andthe silicon oxide background were passivated with PEG to resist proteinadsorption and cell adhesion. Cellular morphology and IR spectra ofsingle, double, and triple cells on gold electrodes exposed tolipopolysaccharide (LPS) of different concentrations were compared toreveal the detection capabilities of these biosensors. The single-cellbased sensors were found to generate the most significant IR wave numbervariation and thus provide the highest detection sensitivity. Changes inmorphology and IR spectrum for single cells exposed to LPS were found tobe time- and concentration-dependent and correlated with each other verywell. FTIR spectra from single cell arrays of gold electrodes withsurface area of 25 mu-m2, 100 mu-m2, and 400 mu-m2 were acquired usingboth synchrotron and conventional FTIR spectromicroscopes to study thesensitivity of detection. The results indicated that the developedsingle-cell platform can be used with conventional FTIRspectromicroscopy. This technique provides real-time, label-free, andrapid bacterial detection, and may allow for statistic and highthroughput analyses, and portability.

  11. ORIENTATION EFFECTS IN THE K-ABSORPTION OF LINEARLY POLARIZED SYNCHROTRON RADIATION IN A GALLIUM SINGLE-CRYSTAL

    NARCIS (Netherlands)

    WEBER, WM; STAPEL, C

    K-absorption spectra of a gallium single crystal were measured with highly polarized synchrotron radiation for two orientations of the electric vector in the absorber: along the crystallographic a and b axes, respectively. The spectra, and small, anisotropic alterations in shape, positions, and

  12. Infrared response of YBa2Cu3O7-δ films to pulsed, broadband synchrotron radiation

    International Nuclear Information System (INIS)

    Carr, G.L.; Quijada, M.; Tanner, D.B.; Etemad, S.; DeRosa, F.; Venkatesan, T.; Dutta, B.; Hemmick, D.; Xi, X.

    1990-01-01

    We report studies of a thin high T c film operating as a fast bolometric detector of infrared radiation. The film has a response of infrared radiation. The film has a response of several mV when exposed to a 1 W, 1 ns duration broadband infrared pulse. The decay after the pulse was about 4 ns. The temperature dependence of the response accurately tracked dR/dT. A thermal model, in which the film's temperature varies relative to the substrate, provides a good description of the response. We find no evidence for other (non-bolometric) response mechanisms for temperatures near or well below T c . 13 refs., 4 figs

  13. Measurement of flow fluctuations in single longitudinal mode pulsed ...

    Indian Academy of Sciences (India)

    2014-02-12

    Feb 12, 2014 ... A simple technique had been demonstrated for measuring flow-induced fluctuations in the single longitudinal mode (SLM) pulsed dye laser. Two prominent frequency components of 10.74 Hz and 48.83 Hz were present in the output of the Nd:YAG-pumped SLM dye laser. The flow-induced frequency ...

  14. Dose rate effect on micronuclei induction in human blood lymphocytes exposed to single pulse and multiple pulses of electrons.

    Science.gov (United States)

    Acharya, Santhosh; Bhat, N N; Joseph, Praveen; Sanjeev, Ganesh; Sreedevi, B; Narayana, Y

    2011-05-01

    The effects of single pulses and multiple pulses of 7 MV electrons on micronuclei (MN) induction in cytokinesis-blocked human peripheral blood lymphocytes (PBLs) were investigated over a wide range of dose rates per pulse (instantaneous dose rate). PBLs were exposed to graded doses of 2, 3, 4, 6, and 8 Gy of single electron pulses of varying pulse widths at different dose rates per pulse, ranging from 1 × 10(6) Gy s(-1) to 3.2 × 10(8) Gy s(-1). Different dose rates per pulse were achieved by changing the dose per electron pulse by adjusting the beam current and pulse width. MN yields per unit absorbed dose after irradiation with single electron pulses were compared with those of multiple pulses of electrons. A significant decrease in the MN yield with increasing dose rates per pulse was observed, when dose was delivered by a single electron pulse. However, no reduction in the MN yield was observed when dose was delivered by multiple pulses of electrons. The decrease in the yield at high dose rates per pulse suggests possible radical recombination, which leads to decreased biological damage. Cellular response to the presence of very large numbers of chromosomal breaks may also alter the damage.

  15. Effects of low-intensity pulsed ultrasound on new trabecular bone during bone-tendon junction healing in a rabbit model: a synchrotron radiation micro-CT study.

    Directory of Open Access Journals (Sweden)

    Hongbin Lu

    Full Text Available This study was designed to evaluate the effects of low-intensity pulsed ultrasound on bone regeneration during the bone-tendon junction healing process and to explore the application of synchrotron radiation micro computed tomography in three dimensional visualization of the bone-tendon junction to evaluate the microarchitecture of new trabecular bone. Twenty four mature New Zealand rabbits underwent partial patellectomy to establish a bone-tendon junction injury model at the patella-patellar tendon complex. Animals were then divided into low-intensity pulsed ultrasound treatment (20 min/day, 7 times/week and placebo control groups, and were euthanized at week 8 and 16 postoperatively (n = 6 for each group and time point. The patella-patellar tendon specimens were harvested for radiographic, histological and synchrotron radiation micro computed tomography detection. The area of the newly formed bone in the ultrasound group was significantly greater than that of control group at postoperative week 8 and 16. The high resolution three dimensional visualization images of the bone-tendon junction were acquired by synchrotron radiation micro computed tomography. Low-intensity pulsed ultrasound treatment promoted dense and irregular woven bone formation at week 8 with greater bone volume fraction, number and thickness of new trabecular bone but with lower separation. At week 16, ultrasound group specimens contained mature lamellar bone with higher bone volume fraction and thicker trabeculae than that of control group; however, there was no significant difference in separation and number of the new trabecular bone. This study confirms that low-intensity pulsed ultrasound treatment is able to promote bone formation and remodeling of new trabecular bone during the bone-tendon junction healing process in a rabbit model, and the synchrotron radiation micro computed tomography could be applied for three dimensional visualization to quantitatively evaluate

  16. Indentation Size Effects in Single Crystal Copper as Revealed by Synchrotron X-ray Microdiffraction

    Energy Technology Data Exchange (ETDEWEB)

    Feng, G.; Budiman, A. S.; Nix, W. D.; Tamura, N.; Patel, J. R.

    2007-11-19

    The indentation size effect (ISE) has been observed in numerous nanoindentation studies on crystalline materials; it is found that the hardness increases dramatically with decreasing indentation size - a 'smaller is stronger' phenomenon. Some have attributed the ISE to the existence of strain gradients and the geometrically necessary dislocations (GNDs). Since the GND density is directly related to the local lattice curvature, the Scanning X-ray Microdiffraction ({mu}SXRD) technique, which can quantitatively measure relative lattice rotations through the streaking of Laue diffractions, can used to study the strain gradients. The synchrotron {mu}SXRD technique we use - which was developed at the Advanced Light Source (ALS), Berkeley Lab - allows for probing the local plastic behavior of crystals with sub-micrometer resolution. Using this technique, we studied the local plasticity for indentations of different depths in a Cu single crystal. Broadening of Laue diffractions (streaking) was observed, showing local crystal lattice rotation due to the indentation-induced plastic deformation. A quantitative analysis of the streaking allows us to estimate the average GND density in the indentation plastic zones. The size dependence of the hardness, as found by nanoindentation, will be described, and its correlation to the observed lattice rotations will be discussed.

  17. Single qubit operations using microwave hyperbolic secant pulses

    Science.gov (United States)

    Ku, H. S.; Long, J. L.; Wu, X.; Bal, M.; Lake, R. E.; Barnes, Edwin; Economou, Sophia E.; Pappas, D. P.

    2017-10-01

    It has been known since the early days of quantum mechanics that hyperbolic secant pulses possess the unique property that they can perform full-cycle Rabi oscillations on two-level quantum systems independently of the pulse detuning. More recently, it was realized that they induce detuning-controlled phases without changing state populations. Here, we experimentally demonstrate the properties of hyperbolic secant pulses on superconducting transmon qubits and contrast them with the more commonly used Gaussian and square waves. We further show that these properties can be exploited to implement phase gates, nominally without exiting the computational subspace. This enables us to demonstrate a microwave-driven Z rotation with a single control parameter, the detuning.

  18. Synchrotron Radiation

    International Nuclear Information System (INIS)

    Asfour, F.I

    2000-01-01

    Synchrotron light is produced by electron accelerators combined with storage rings. This light is generated over a wide spectral region; from infra-red (IR) through the visible and vacuum ultraviolet (VUV), and into the X-ray region. For relativistic electrons (moving nearly with the speed of light), most radiation is concentrated in a small cone with an opening angle of 1/gamma(some 0.1 to 1 milliradian),where gamma is the electron energy in units of rest energy (typically 10 3 -10 4 ). In synchrotron radiation sources (storage rings) highly relativistic electrons are stored to travel along a circular path for many hours. Radiation is caused by transverse acceleration due to magnetic forces(bending magnets). The radiation is emitted in pulses of 10-20 picosecond, separated by some 2 nanosecond or longer separation

  19. Synchrotron sources

    Energy Technology Data Exchange (ETDEWEB)

    Hulbert, S.L.

    1999-12-13

    Synchrotron radiation is a very bright, broadband, polarized, pulsed source of electromagnetic radiation extending from the infrared to the x-ray region. Brightness, defined as flux per unit area per unit solid angle, is normally a more important quantity than flux or intensity, particularly in throughput limited applications which include those in which monochromators are used. The authors have attempted to compile the formulae needed to calculate the flux, brightness, polarization and power produced by the three standard storage ring synchrotron radiation sources: bending magnets, wigglers and undulators. Where necessary, these formulae have contained reference to the emittance of the electron beam, as well as to the electron beam size and its divergence. For all three type sources, the source phase space area, i.e. the spatial and angular extent of the effective (real) source, is a convolution of its electron and photon components.

  20. Impact of pulse duration on Ho:YAG laser lithotripsy: treatment aspects on the single-pulse level.

    Science.gov (United States)

    Sroka, Ronald; Pongratz, Thomas; Scheib, Gabriel; Khoder, Wael; Stief, Christian G; Herrmann, Thomas; Nagele, Udo; Bader, Markus J

    2015-04-01

    Holmium-YAG (Ho:YAG) laser lithotripsy is a multi-pulse treatment modality with stochastic effects on the fragmentation. In vitro investigation on the single-pulse-induced effects on fiber, repulsion as well as fragmentation was performed to identify potential impacts of different Ho:YAG laser pulse durations. A Ho:YAG laser system (Swiss LaserClast, EMS S.A., Nyon, Switzerland) with selectable long- or short-pulse mode was tested with regard to fiber burn back, the repulsion capacity using an underwater pendulum setup and single-pulse-induced fragmentation capacity using artificial (BEGO) stones. The laser parameters were chosen in accordance with clinical application modes (laser fiber: 365 and 200 µm; output power: 4, 6 and 10 W in different combinations of energy per pulse and repetition rate). Evaluation parameters were reduction in fiber length, pendulum deviation and topology of the crater. Using the long-pulse mode, the fiber burn back was nearly negligible, while in short-pulse mode, an increased burn back could be observed. The results of the pendulum test showed that the deviation induced by the momentum of short pulses was by factor 1.5-2 higher compared to longer pulses at identical energy per pulse settings. The ablation volumes induced by single pulses either in short-pulse or long-pulse mode did not differ significantly although different crater shapes appeared. Reduced stone repulsion and reduced laser fiber burn back with longer laser pulses may result in a more convenient handling during clinical application and thus in an improved clinical outcome of laser lithotripsy.

  1. 1540-nm single frequency single-mode pulsed all fiber laser for coherent Doppler lidar

    Science.gov (United States)

    Zhang, Xin; Diao, Weifeng; Liu, Yuan; Liu, Jiqiao; Hou, Xia; Chen, Weibiao

    2015-02-01

    A single-mode single frequency eye-safe pulsed all fiber laser based on master oscillator power amplification structure is presented. This laser is composed of a narrow linewidth distributed laser diode seed laser and two-stage cascade amplifiers. 0.8 m longitudinally gradient strained erbium/ytterbium co-doped polarization-maintaining fiber with a core diameter of 10 μm is used as the gain fiber and two acoustic-optics modulators are adopted to enhance pulse extinction ratio. A peak power of 160 W and a pulse width of 200 ns at 10 kHz repetition rate are achieved with transform-limited linewidth and diffraction-limited beam quality. This laser will be employed in a compact short range coherent Doppler wind lidar.

  2. Synchrotron light; Lumiere synchrotron

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    'Synchrotron Light' is an interactive and detailed introduction to the physics and technology of the generation of coherent radiation from accelerators as well as to its widespread high-tech applications in science, medicine and engineering. The topics covered are the interaction of light and matter, the technology of synchrotron light sources, spectroscopy, imaging, scattering and diffraction of X-rays, and applications to materials science, biology, biochemistry, medicine, chemistry, food and pharmaceutical technology. All synchrotron light facilities are introduced with their home-page addresses. 'Synchrotron Light' provides an instructive and comprehensive multimedia learning tool for students, experienced practitioners and novices wishing to apply synchrotron radiation in their future work. Its multiple-entry points permit an easy exploration of the CD-Rom according to the users knowledge and interest. 2-D and 3-D animations and virtual reconstruction with computer-generated images guide visitors into the scientific and technical world of a synchrotron and into the applications of synchrotron radiation. This bilingual (English and French) CD-Rom can be used for self-teaching and in courses at various levels in physics, chemistry, engineering, and biology. (author)

  3. Pulse plating of Pt on n-GaAs (1 0 0) wafer surfaces: Synchrotron induced photoelectron spectroscopy and XPS of wet fabrication processes

    International Nuclear Information System (INIS)

    Ensling, D.; Hunger, R.; Kraft, D.; Mayer, Th.; Jaegermann, W.; Rodriguez-Girones, M.; Ichizli, V.; Hartnagel, H.L.

    2003-01-01

    Preparation steps of Pt/n-GaAs Schottky contacts as applied in the fabrication process of varactor diode arrays for THz applications are analysed by photoelectron spectroscopy. Pulsed cathodic deposition of Pt onto GaAs (1 0 0) wafer surfaces from acidic solution has been studied by core level photoelectron spectroscopy using different excitation energies. A laboratory AlKα source as well as synchrotron radiation of hν=130 and 645 eV at BESSY was used. Chemical analyses and semiquantitative estimates of layer thickness are given for the natural oxide of an untreated wafer surface, a surface conditioning NH 3 etching step, and stepwise pulse plating of Pt. The structural arrangement of the detected species and interface potentials are considered

  4. Touch stimulated pulse generation in biomimetic single-layer graphene

    Science.gov (United States)

    Sul, Onejae; Chun, Hyunsuk; Choi, Eunseok; Choi, Jungbong; Cho, Kyeongwon; Jang, Dongpyo; Chun, Sungwoo; Park, Wanjun; Lee, Seung-Beck

    2016-02-01

    Detecting variation in contact pressure is a separate sensing mode in the human somatosensory system that differs from the detection of pressure magnitude. If pressure magnitude and variation sensing can be achieved simultaneously, an advanced biomimetic tactile system that better emulates human senses may be developed. We report on a novel single-layer graphene based artificial mechanoreceptor that generates a resistance pulse as the contact stimulus passes a specific threshold pressure, mimicking the generation of action potentials in a biological fast-adapting mechanoreceptor. The electric field from a flexible membrane gate electrode placed above a graphene channel raises the Fermi level from the valence band as pressure deflects the membrane. The threshold pressure is reached when the Fermi level crosses the Dirac point in the graphene energy band, which generates a sharp peak in the measured resistance. We found that by changing the gate potential it was possible to modulate the threshold pressure and using a series of graphene channels, a train of pulses were generated during a transient pressurizing stimulus demonstrating biomimetic behaviour.Detecting variation in contact pressure is a separate sensing mode in the human somatosensory system that differs from the detection of pressure magnitude. If pressure magnitude and variation sensing can be achieved simultaneously, an advanced biomimetic tactile system that better emulates human senses may be developed. We report on a novel single-layer graphene based artificial mechanoreceptor that generates a resistance pulse as the contact stimulus passes a specific threshold pressure, mimicking the generation of action potentials in a biological fast-adapting mechanoreceptor. The electric field from a flexible membrane gate electrode placed above a graphene channel raises the Fermi level from the valence band as pressure deflects the membrane. The threshold pressure is reached when the Fermi level crosses the Dirac

  5. Single and double long pulse laser ablation of aluminum induced in air and water ambient

    Energy Technology Data Exchange (ETDEWEB)

    Akbari Jafarabadi, Marzieh; Mahdieh, Mohammad Hossein, E-mail: mahdm@iust.ac.ir

    2017-02-28

    Highlights: • Laser ablation of aluminum target by single and double pulse (∼ 5 ns delay) in ambient air and distilled water • Comparing with air, in ambient water, plasma confinement results in higher crater depth. • In comparison with single pulse laser ablation, the absorption of the laser pulse energy is higher for double pulse regime. • As a result of ablated material expansion, the crater depth is decreased if the target is placed at lower depth. - Abstract: In this paper, single pulse and double pulse laser ablation of an aluminum target in two interaction ambient was investigated experimentally. The interaction was performed by nanosecond Nd:YAG laser beam in air and four depths (i.e. 9, 13, 17, and 21 mm) of distilled water ambient. The irradiation was carried out in single and collinear double pulse configurations in both air and liquid ambient. Crater geometry (depth and diameter) was measured by an optical microscope. The results indicated that the crater geometry strongly depends on both single pulse and double pulse configurations and interaction ambient. In single pulse regime, the crater diameter is higher for all water depths compared to that of air. However, the crater depth, depend on water depth, is higher or lower than the crater depth in air. In double pulse laser ablation, there are greater values for both crater diameters and crater depths in the water.

  6. Measuring charge density of electron beam single nanosecond pulses

    International Nuclear Information System (INIS)

    Gonchar, A.I.; Nesterenko, V.S.; Fazkullin, V.A.

    1982-01-01

    A description is presented of a probe design and electrometric repeater circuit and technique for measuring the charge (current) density of electron beam single pulses by integrating current at a reference capacitor with a subsequent registering of voltage across the capacitor. The probe consists of a band-type signal electrodes and two oval cross-section sleeves: external and internal with larger and smaller rectangular openings, respectively. The external sleeve has antidynatron grid located over the hole. The design employs integer nickel sleever - the cores of electron tube cathodes. The signal electrode is made of nickel band 0.15 mm thick. The probe elements are insulated from each other along the whole length with a layer of teflon band (30 μm), with rectangular openings cut in compliance with the sleeve openings. The measurement range is from 0.4x10 - 9 to 1x10 - 7 C/cm 2 . The rated accuracy of measurements is no worse than +-5% for the beam energy of 0.2 to 3 KeV. The ultimate parameters the charge density - 6 C/cm 2 and direct current density 3 mA/cm 2 - are specified by the breakdown voltage (200 V) of the input capacitor and probe insulation

  7. Nonlinear pulse propagation in a single-and a few-cycle regimes ...

    Indian Academy of Sciences (India)

    The propagation equation for a single- and a few-cycle pulses was derived in a cubic nonlinear medium including the Raman response. Using this equation, the propagation characteristics of a single- and a 4-cycle pulse, at 0.8 m wavelength, were studied numerically in one spatial dimension. It was shown that Raman ...

  8. Single attosecond pulse from terahertz-assisted high-order harmonic generation

    Science.gov (United States)

    Balogh, Emeric; Kovacs, Katalin; Dombi, Peter; Fulop, Jozsef A.; Farkas, Gyozo; Hebling, Janos; Tosa, Valer; Varju, Katalin

    2011-08-01

    High-order harmonic generation by few-cycle 800 nm laser pulses in neon gas in the presence of a strong terahertz (THz) field is investigated numerically with propagation effects taken into account. Our calculations show that the combination of THz fields with up to 12 fs laser pulses can be an effective gating technique to generate single attosecond pulses. We show that in the presence of the strong THz field only a single attosecond burst can be phase matched, whereas radiation emitted during other half cycles disappears during propagation. The cutoff is extended and a wide supercontinuum appears in the near-field spectra, extending the available spectral width for isolated attosecond pulse generation from 23 to 93 eV. We demonstrate that phase-matching effects are responsible for the generation of isolated attosecond pulses, even in conditions when single-atom response yields an attosecond pulse train.

  9. Single attosecond pulse from terahertz-assisted high-order harmonic generation

    International Nuclear Information System (INIS)

    Balogh, Emeric; Kovacs, Katalin; Dombi, Peter; Farkas, Gyozo; Fulop, Jozsef A.; Hebling, Janos; Tosa, Valer; Varju, Katalin

    2011-01-01

    High-order harmonic generation by few-cycle 800 nm laser pulses in neon gas in the presence of a strong terahertz (THz) field is investigated numerically with propagation effects taken into account. Our calculations show that the combination of THz fields with up to 12 fs laser pulses can be an effective gating technique to generate single attosecond pulses. We show that in the presence of the strong THz field only a single attosecond burst can be phase matched, whereas radiation emitted during other half cycles disappears during propagation. The cutoff is extended and a wide supercontinuum appears in the near-field spectra, extending the available spectral width for isolated attosecond pulse generation from 23 to 93 eV. We demonstrate that phase-matching effects are responsible for the generation of isolated attosecond pulses, even in conditions when single-atom response yields an attosecond pulse train.

  10. Single attosecond pulse from terahertz-assisted high-order harmonic generation

    Energy Technology Data Exchange (ETDEWEB)

    Balogh, Emeric [Department of Optics and Quantum Electronics, University of Szeged, H-6701 Szeged (Hungary); Kovacs, Katalin [Department of Optics and Quantum Electronics, University of Szeged, H-6701 Szeged (Hungary); National Institute for R and D of Isotopic and Molecular Technologies, RO-400293 Cluj-Napoca (Romania); Dombi, Peter; Farkas, Gyozo [Research Institute for Solid State Physics and Optics, H-1525 Budapest (Hungary); Fulop, Jozsef A.; Hebling, Janos [Department of Experimental Physics, University of Pecs, H-7624 Pecs (Hungary); Tosa, Valer [National Institute for R and D of Isotopic and Molecular Technologies, RO-400293 Cluj-Napoca (Romania); Varju, Katalin [HAS Research Group on Laser Physics, University of Szeged, H-6701 Szeged (Hungary)

    2011-08-15

    High-order harmonic generation by few-cycle 800 nm laser pulses in neon gas in the presence of a strong terahertz (THz) field is investigated numerically with propagation effects taken into account. Our calculations show that the combination of THz fields with up to 12 fs laser pulses can be an effective gating technique to generate single attosecond pulses. We show that in the presence of the strong THz field only a single attosecond burst can be phase matched, whereas radiation emitted during other half cycles disappears during propagation. The cutoff is extended and a wide supercontinuum appears in the near-field spectra, extending the available spectral width for isolated attosecond pulse generation from 23 to 93 eV. We demonstrate that phase-matching effects are responsible for the generation of isolated attosecond pulses, even in conditions when single-atom response yields an attosecond pulse train.

  11. Airfoil sampling of a pulsed Laval beam with tunable vacuum ultraviolet (VUV) synchrotron ionization quadrupole mass spectrometry: Application to low--temperature kinetics and product detection

    Energy Technology Data Exchange (ETDEWEB)

    Soorkia, Satchin; Liu, Chen-Lin; Savee, John D; Ferrell, Sarah J; Leone, Stephen R; Wilson, Kevin R

    2011-10-12

    A new pulsed Laval nozzle apparatus with vacuum ultraviolet (VUV) synchrotron photoionization quadrupole mass spectrometry is constructed to study low-temperature radicalneutralchemical reactions of importance for modeling the atmosphere of Titan and the outer planets. A design for the sampling geometry of a pulsed Laval nozzle expansion has beendeveloped that operates successfully for the determination of rate coefficients by time-resolved mass spectrometry. The new concept employs airfoil sampling of the collimated expansion withexcellent sampling throughput. Time-resolved profiles of the high Mach number gas flow obtained by photoionization signals show that perturbation of the collimated expansion by theairfoil is negligible. The reaction of C2H with C2H2 is studied at 70 K as a proof-of-principle result for both low-temperature rate coefficient measurements and product identification basedon the photoionization spectrum of the reaction product versus VUV photon energy. This approach can be used to provide new insights into reaction mechanisms occurring at kinetic ratesclose to the collision-determined limit.

  12. X-ray diffraction studies on single and mixed confectionery fats using synchrotron radiation

    Energy Technology Data Exchange (ETDEWEB)

    MacMillan, S.C.; Roberts, K.J.; Wells, M.; Polgreen, M.; Smith, I. [Heriot-Watt University, Edinburgh, (United Kingdom). Department of Mechanical and Chemical Engineering, Centre for Molecular and Interface Engineering

    1999-12-01

    and stirring rate (shear rate). The X-rays used are from a high intensity synchrotron radiation source, enabling polymorphic phase transformations for a variety of fat mixtures to observed. Copyright (1999) Australian X-ray Analytical Association Inc.

  13. X-ray diffraction studies on single and mixed confectionery fats using synchrotron radiation

    International Nuclear Information System (INIS)

    MacMillan, S.C.; Roberts, K.J.; Wells, M.; Polgreen, M.; Smith, I.

    1999-01-01

    and stirring rate (shear rate). The X-rays used are from a high intensity synchrotron radiation source, enabling polymorphic phase transformations for a variety of fat mixtures to observed. Copyright (1999) Australian X-ray Analytical Association Inc

  14. Graphene based widely-tunable and singly-polarized pulse generation with random fiber lasers

    Science.gov (United States)

    Yao, B. C.; Rao, Y. J.; Wang, Z. N.; Wu, Y.; Zhou, J. H.; Wu, H.; Fan, M. Q.; Cao, X. L.; Zhang, W. L.; Chen, Y. F.; Li, Y. R.; Churkin, D.; Turitsyn, S.; Wong, C. W.

    2015-12-01

    Pulse generation often requires a stabilized cavity and its corresponding mode structure for initial phase-locking. Contrastingly, modeless cavity-free random lasers provide new possibilities for high quantum efficiency lasing that could potentially be widely tunable spectrally and temporally. Pulse generation in random lasers, however, has remained elusive since the discovery of modeless gain lasing. Here we report coherent pulse generation with modeless random lasers based on the unique polarization selectivity and broadband saturable absorption of monolayer graphene. Simultaneous temporal compression of cavity-free pulses are observed with such a polarization modulation, along with a broadly-tunable pulsewidth across two orders of magnitude down to 900 ps, a broadly-tunable repetition rate across three orders of magnitude up to 3 MHz, and a singly-polarized pulse train at 41 dB extinction ratio, about an order of magnitude larger than conventional pulsed fiber lasers. Moreover, our graphene-based pulse formation also demonstrates robust pulse-to-pulse stability and wide-wavelength operation due to the cavity-less feature. Such a graphene-based architecture not only provides a tunable pulsed random laser for fiber-optic sensing, speckle-free imaging, and laser-material processing, but also a new way for the non-random CW fiber lasers to generate widely tunable and singly-polarized pulses.

  15. Study on irradiation effects of nucleus electromagnetic pulse on single chip computer system

    International Nuclear Information System (INIS)

    Hou Minsheng; Liu Shanghe; Wang Shuping

    2001-01-01

    Intense electromagnetic pulse, namely nucleus electromagnetic pulse (NEMP), lightning electromagnetic pulse (LEMP) and high power microwave (HPM), can disturb and destroy the single chip computer system. To study this issue, the authors made irradiation experiments by NEMPs generated by gigahertz transversal electromagnetic (GTEM) Cell. The experiments show that shutdown, restarting, communication errors of the single chip microcomputer system would occur when it was irradiated by the NEMPs. Based on the experiments, the cause on the effects on the single chip microcomputer system is discussed

  16. Self-phase modulation of a single-cycle THz pulse

    DEFF Research Database (Denmark)

    Turchinovich, Dmitry; Hvam, Jørn Märcher; Hoffmann, M. C.

    2013-01-01

    We demonstrate self-phase modulation (SPM) of a single-cycle THz pulse in a semiconductor, using bulk n-GaAs as a model system. The SPM arises from the heating of free electrons in the electric field of the THz pulse. Electron heating leads to an ultrafast reduction of the plasma frequency, which...

  17. Observation of self-pulsing in singly resonant optical second-harmonic generation with competing nonlinearities

    DEFF Research Database (Denmark)

    Bache, Morten; Lodahl, Peter; Mamaev, Alexander V.

    2002-01-01

    We predict and experimentally observe temporal self-pulsing in singly resonant intracavity second-harmonic generation under conditions of simultaneous parametric oscillation. The threshold for self-pulsing as a function of cavity tuning and phase mismatch are found from analysis of a three-compon...

  18. A device for the application of uniaxial strain to single crystal samples for use in synchrotron radiation experiments

    Energy Technology Data Exchange (ETDEWEB)

    Gannon, L. [Clarendon Laboratory, University of Oxford Physics Department, Parks Road, Oxford OX1 3PU (United Kingdom); Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 ODE (United Kingdom); Bosak, A. [European Synchrotron Radiation Facility, BP 220, F-38043 Grenoble Cedex (France); Burkovsky, R. G. [European Synchrotron Radiation Facility, BP 220, F-38043 Grenoble Cedex (France); Peter the Great Saint-Petersburg Polytechnic University, 29 Politekhnicheskaya, 195251, St.-Petersburg (Russian Federation); Nisbet, G.; Hoesch, M., E-mail: Moritz.Hoesch@diamond.ac.uk [Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 ODE (United Kingdom); Petrović, A. P. [DPMC-MaNEP, Université de Genève, Quai Ernest-Ansermet 24, 1211 Genève 4 (Switzerland)

    2015-10-15

    We present the design, construction, and testing of a straining device compatible with many different synchrotron radiation techniques, in a wide range of experimental environments (including low temperature, high field and ultra-high vacuum). The device has been tested by X-ray diffraction on single crystal samples of quasi-one-dimensional Cs{sub 2}Mo{sub 6}Se{sub 6} and K{sub 2}Mo{sub 6}Se{sub 6}, in which microscopic strains up to a Δc/c = 0.12% ± 0.01% change in the c lattice parameters have been achieved. We have also used the device in an inelastic X-ray scattering experiment, to probe the strain-dependent speed of sound ν along the c axis. A reduction Δν/ν of up to −3.8% was obtained at a strain of Δc/c = 0.25% in K{sub 2}Mo{sub 6}Se{sub 6}.

  19. Single Pulse Electrical Stimulation to identify epileptogenic cortex : Clinical information obtained from early evoked responses

    NARCIS (Netherlands)

    Mouthaan, B.E.; van 't Klooster, M.A.; Keizer, D.; Hebbink, G.J.; Leijten, F.S.S.; Ferrier, C.H.; van Putten, M.J.A.M.; Zijlmans, M.; Huiskamp, G.J.M.

    Objective: Single Pulse Electrical Stimulation (SPES) probes epileptogenic cortex during electrocorticography. Two SPES responses are described: pathological delayed responses (DR, >100 ms) associated with the seizure onset zone (SOZ) and physiological early responses (ER, <100 ms) that map cortical

  20. Pulsed, Single-Frequency, 2-um Seed Source for Coherent LIDAR Applications, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The primary objective of the proposed Phase I effort is to develop and demonstrate a low-average power, pulsed, single-frequency, 2-um Ho-laser source for...

  1. High energy nanosecond laser pulses delivered single-mode through hollow-core PBG fibers.

    Science.gov (United States)

    Shephard, Jonathan; Jones, J; Hand, D; Bouwmans, G; Knight, J; Russell, P; Mangan, B

    2004-02-23

    We report on the development of hollow-core photonic bandgap fibers for the delivery of high energy pulses for precision micromachining applications. Short pulses of (65ns pulse width) and energies of the order of 0.37mJ have been delivered in a single spatial mode through hollow-core photonic bandgap fibers at 1064nm using a high repetition rate (15kHz) Nd:YAG laser. The ultimate laser-induced damage threshold and practical limitations of current hollow-core fibers for the delivery of short optical pulses are discussed.

  2. The Israeli EA-FEL Upgrade Towards Long Pulse Operation for Ultra-High Resolution Single Pulse Coherent Spectroscopy

    CERN Document Server

    Gover, A; Kanter, M; Kapilevich, B; Litvak, B; Peleg, S; Socol, Y; Volshonok, M

    2005-01-01

    The Israeli Electrostatic Accelerator FEL (EA-FEL) is now being upgraded towards long pulse (1005s) operation and ultra-high resolution (10(-6)) single pulse coherent spectroscopy. We present quantitative estimations regarding the applications of controlled radiation chirp for spectroscopic applications with pulse-time Fourier Transform limited spectral resolution. Additionally, we describe a novel extraction-efficiency-improving scheme based on increase of accelerating voltage (boosting) after saturation is achieved. The efficiency of the proposed scheme is confirmed by theoretical and numerical calculations. The latter are performed using software, based on 3D space-frequency domain model. The presentation provides an overview of the upgrade status: the high-voltage terminal is being reconfigured to accept the accelerating voltage boost system; a new broad band low-loss resonator is being manufactured; multi-stage depressed collector is assembled.

  3. Pulsed laser simulation of VLSI single-event effect testing study

    International Nuclear Information System (INIS)

    Xue Yuxiong; Cao Zhou Yang Shiyu; Tian Kai; Liu Shufen; Chu Nan; Cao Haining; Shang Zhi

    2008-01-01

    This paper describes a study aimed at investigating the pulsed laser simulation of Single-Event Effect (SEE) testing for VLSI Intel386EX CPU, using our laboratory LSS (laser simulation system). We have detailed SEE testing principle, testing method, testing system constituting, testing result. It validates that our laser pulses simulate may use SEE testing in VLSI, and Intel 386Ex have a large locking resistance to single event. (authors)

  4. Cooling the vertical surface by conditionally single pulses

    Directory of Open Access Journals (Sweden)

    Karpov Pavel

    2017-01-01

    Full Text Available You Sprays with periodic supply of the droplet phase have great opportunities to control the heat exchange processes. Varying pulse duration and frequency of their repetition, we can achieve the optimal conditions of evaporative cooling with minimization of the liquid flow rate. The paper presents experimental data on studying local heat transfer on a large subcooled surface, obtained on the original setup with multinozzle controlled system of impact irrigation by the gas-droplet flow. A contribution to intensification of the spray parameters (flow rate, pulse duration, repetition frequency per a growth of integral heat transfer was studied. Data on instantaneous distribution of the heat flux value helped us to describe the processes occurring on the studied surface. These data could describe the regime of “island” film cooling.

  5. Cooling the vertical surface by conditionally single pulses

    Science.gov (United States)

    Karpov, Pavel; Nazarov, Alexander; Serov, Anatoly; Terekhov, Victor

    2017-10-01

    You Sprays with periodic supply of the droplet phase have great opportunities to control the heat exchange processes. Varying pulse duration and frequency of their repetition, we can achieve the optimal conditions of evaporative cooling with minimization of the liquid flow rate. The paper presents experimental data on studying local heat transfer on a large subcooled surface, obtained on the original setup with multinozzle controlled system of impact irrigation by the gas-droplet flow. A contribution to intensification of the spray parameters (flow rate, pulse duration, repetition frequency) per a growth of integral heat transfer was studied. Data on instantaneous distribution of the heat flux value helped us to describe the processes occurring on the studied surface. These data could describe the regime of "island" film cooling.

  6. Optimization And Single-Shot Characterization Of Ultrashort Thz Pulses From A Laser Wakefield Accelerator

    International Nuclear Information System (INIS)

    Plateau, G.R.; Matlis, N.H.; van Tilborg, J.; Geddes, C.G.R.; Toth, Cs.; Schroeder, C.B.; Leemans, W.P.

    2009-01-01

    We present spatiotemporal characterization of μJ-class ultrashort THz pulses generated from a laser wakefield accelerator (LWFA). Accelerated electrons, resulting from the interaction of a high-intensity laser pulse with a plasma, emit high-intensity THz pulses as coherent transition radiation. Such high peak-power THz pulses, suitable for high-field (MV/cm) pump-probe experiments, also provide a non-invasive bunch-length diagnostic and thus feedback for the accelerator. The characterization of the THz pulses includes energy measurement using a Golay cell, 2D sign-resolved electro-optic measurement and single-shot spatiotemporal electric-field distribution retrieval using a new technique, coined temporal electric-field cross-Correlation (TEX). All three techniques corroborate THz pulses of ∼ 5 μJ, with peak fields of 100's of kV/cm and ∼ 0.4 ps rms duration.

  7. Femtosecond laser ablation of silver foil with single and double pulses

    CSIR Research Space (South Africa)

    Roberts, DE

    2009-01-01

    Full Text Available /apsusc r ablation of silver foil with single and double pulses, Appl. Surf. D.E. Roberts et al. / Applied Surface Science xxx (2009) xxx–xxx2 G Model APSUSC-19322; No of Pages 9 pulses used for ablation. While there has been much overlap in the aims... value r ablation of silver foil with single and double pulses, Appl. Surf. ; lon D.E. Roberts et al. / Applied Surface Science xxx (2009) xxx–xxx 3 G Model APSUSC-19322; No of Pages 9 Fig. 1. Surface temperature versus time calculated for double...

  8. Catastrophic optical mirror damage in diode lasers monitored during single-pulse operation

    DEFF Research Database (Denmark)

    Zegler, M.; Tomm, J.W.; Reeber, D.

    2009-01-01

    Catastrophic optical mirror damage (COMD) is analyzed for 808 nm emitting diode lasers in single-pulse operation in order to separate facet degradation from subsequent degradation processes. During each pulse, nearfield and thermal images are monitored. A temporal resolution better than 7 µs...... is achieved. The thermal runaway process is unambiguously related to the occurrence of a “thermal flash.” A one-by-one correlation between nearfield, thermal flash, thermal runaway, and structural damage is observed. The single-pulse excitation technique allows for controlling the propagation...

  9. Synchrotron radiation

    CERN Document Server

    Kunz, C

    1974-01-01

    The production of synchrotron radiation as a by-product of circular high-energy electron (positron) accelerators or storage rings is briefly discussed. A listing of existing or planned synchrotron radiation laboratories is included. The following properties are discussed: spectrum, collimation, polarization, and intensity; a short comparison with other sources (lasers and X-ray tubes) is also given. The remainder of the paper describes the experimental installations at the Deutsches Elektronen-Synchrotron (DESY) and DORIS storage rings, presents a few typical examples out of the fields of atomic, molecular, and solid-state spectroscopy, and finishes with an outlook on the use of synchrotron radiation in molecular biology. (21 refs).

  10. Synchrotron radiation infrared microspectroscopy of single living cells in microfluidic devices: advantages, disadvantages and future perspectives

    International Nuclear Information System (INIS)

    Vaccari, L; Birarda, G; Grenci, G; Pacor, S; Businaro, L

    2012-01-01

    The possibility to fully exploit the diagnostic capabilities of SR-IRMS for studying single living cells under physiological conditions is limited by several constrains. First of all, the technology for manufacturing materials transparent to both IR and visible light is quite immature, limiting the design of fluidic devices to simple demountable liquid cells. In addition, the water spectral features become prominent in the Mid IR, hiding several cellular bands and therefore limiting the diagnostic capabilities of SR-IRMS. The overcoming of the so called 'water absorption barrier' requires the improvement of the protocols for the compensation of buffer spectral contributions, a goal that can be achieved also advancing the quality of IR-suitable fluidic devices. In this paper, the technical solutions employed for microfabricating completely sealed IR-visible transparent fluidic devices for living cell analysis will be presented. Several examples of the results obtained in the study of living U937 monocytes subjected to different stimuli will be selected for highlighting both the advantages and the disadvantages offered by our approach for cellular biology.

  11. Imaging and electron energy-loss spectroscopy using single nanosecond electron pulses.

    Science.gov (United States)

    Picher, Matthieu; Bücker, Kerstin; LaGrange, Thomas; Banhart, Florian

    2018-03-13

    We implement a parametric study with single electron pulses having a 7 ns duration to find the optimal conditions for imaging, diffraction, and electron energy-loss spectroscopy (EELS) in the single-shot approach. Photoelectron pulses are generated by illuminating a flat tantalum cathode with 213 nm nanosecond laser pulses in a 200 kV transmission electron microscope (TEM) with thermionic gun and Wehnelt electrode. For the first time, an EEL spectrometer is used to measure the energy distribution of single nanosecond electron pulses which is crucial for understanding the ideal imaging conditions of the single-shot approach. By varying the laser power, the Wehnelt bias, and the condenser lens settings, the optimum TEM operation conditions for the single-shot approach are revealed. Due to space charge and the Boersch effect, the energy width of the pulses under maximized emission conditions is far too high for imaging or spectroscopy. However, by using the Wehnelt electrode as an energy filter, the energy width of the pulses can be reduced to 2 eV, though at the expense of intensity. The first EEL spectra taken with nanosecond electron pulses are shown in this study. With 7 ns pulses, an image resolution of 25 nm is attained. It is shown how the spherical and chromatic aberrations of the objective lens as well as shot noise limit the resolution. We summarize by giving perspectives for improving the single-shot time-resolved approach by using aberration correction. Copyright © 2018 Elsevier B.V. All rights reserved.

  12. Physics and technology of tunable pulsed single longitudinal mode ...

    Indian Academy of Sciences (India)

    Design and technology demonstration of compact, narrow bandwidth, high repetition rate, tunable SLM dye lasers in two different configurations, namely Littrow and grazing incidence grating (GIG), were carried out in our lab at BARC, India. The single longitudinal mode (SLM) dye laser generates single-mode laser beams ...

  13. Physics and technology of tunable pulsed single longitudinal mode ...

    Indian Academy of Sciences (India)

    The single longitudinal mode (SLM) dye laser generates single-mode laser beams of ∼ 400 MHz (GIG configuration) and ∼ 600 MHz (Littrow configuration) bandwidth. Detailed performance studies of the Littrow and GIG dye laser resonators showed that GIG dye laser results in narrower linewidth and broad mode hop free ...

  14. Synchrotron radiation

    International Nuclear Information System (INIS)

    Nave, C.; Quinn, P.; Blake, R.J.

    1988-01-01

    The paper on Synchrotron Radiation contains the appendix to the Daresbury Annual Report 1987/88. The appendix is mainly devoted to the scientific progress reports on the work at the Synchrotron Radiation Source in 1987/8. The parameters of the Experimental Stations and the index to the Scientific Reports are also included in the appendix. (U.K.)

  15. Magnetic phases in Pt/Co/Pt films induced by single and multiple femtosecond laser pulses

    International Nuclear Information System (INIS)

    Kisielewski, J.; Kurant, Z.; Sveklo, I.; Tekielak, M.; Maziewski, A.; Wawro, A.

    2016-01-01

    Ultrathin Pt/Co/Pt trilayers with initial in-plane magnetization were irradiated with femtosecond laser pulses. In this way, an irreversible structural modification was introduced, which resulted in the creation of numerous pulse fluence-dependent magnetic phases. This was particularly true with the out-of-plane magnetization state, which exhibited a submicrometer domain structure. This effect was studied in a broad range of pulse fluences up to the point of ablation of the metallic films. In addition to this single-pulse experiment, multiple exposure spots were also investigated, which exhibited an extended area of out-of-plane magnetization phases and a decreased damage threshold. Using a double exposure with partially overlapped spots, a two-dimensional diagram of the magnetic phases as a function of the two energy densities was built, which showed a strong inequality between the first and second incoming pulses.

  16. Method for single-shot measurement of picosecond laser pulse-lengths without electronic time dispersion

    International Nuclear Information System (INIS)

    Kyrala, G.A.

    1987-01-01

    A two-source shear pattern recording is proposed as a method for single-shot measurement of the pulse shape from nearly monochromatic sources whose pulse lengths are shorter than their coherence times. The basis of this method relies on the assertion that if two identical electromagnetic pulses are recombined with a time delay greater than the sum of their pulse widths, the recordable spatial pattern has no fringes in it. At an arbitrary delay, translated into an actual spatial recording position, the recorded modulated intensity will sample the corresponding laser intensity at that delay time, but with a modulation due to the coherence function of the electromagnetic pulse. Two arrangements are proposed for recording the pattern. The principles, the design parameters, and the methodologies of these arrangements are presented. Resolutions of the configurations and their limitations are given as well

  17. A pulsed single-frequency Nd:GGG/BaWO4 Raman laser

    Science.gov (United States)

    Liu, Zhaojun; Men, Shaojie; Cong, Zhenhua; Qin, Zengguang; Zhang, Xingyu; Zhang, Huaijin

    2018-04-01

    A single-frequency pulsed laser at 1178.3 nm was demonstrated in a crystalline Raman laser. A crystal combination of Nd:GGG and BaWO4 was selected to realize Raman conversion from a 1062.5 nm fundamental wave to a 1178.3 nm Stokes wave. An entangled cavity was specially designed to form an intracavity Raman configuration. Single-longitudinal-mode operation was realized by introducing two Fabry–Perot etalons into the Raman laser cavity. This laser operated at a pulse repetition rate of 50 Hz with 2 ms long envelopes containing micro pulses at a 30 kHz repetition rate. The highest output power was 41 mW with the micro pulse duration of 15 ns. The linewidth was measured to be less than 130 MHz.

  18. Development of single frame X-ray framing camera for pulsed ...

    Indian Academy of Sciences (India)

    X-ray emission from a laser-produced copper plasma. A reduction factor of ∼6·5 is seen in the dark ... 30 J, 2 ns (FWHM) Nd:glass laser on a copper target. 2. System description. A schematic diagram of the .... using this construction, we can get clean single pulse width upto τ. Pulse amplitude can be changed by changing ...

  19. A Single-Chip CMOS Pulse Oximeter with On-Chip Lock-In Detection

    OpenAIRE

    Diwei He; Stephen P. Morgan; Dimitrios Trachanis; Jan van Hese; Dimitris Drogoudis; Franco Fummi; Francesco Stefanni; Valerio Guarnieri; Barrie R. Hayes-Gill

    2015-01-01

    Pulse oximetry is a noninvasive and continuous method for monitoring the blood oxygen saturation level. This paper presents the design and testing of a single-chip pulse oximeter fabricated in a 0.35 ?m CMOS process. The chip includes photodiode, transimpedance amplifier, analogue band-pass filters, analogue-to-digital converters, digital signal processor and LED timing control. The experimentally measured AC and DC characteristics of individual circuits including the DC output voltage of the...

  20. Synchrotron light

    International Nuclear Information System (INIS)

    2001-01-01

    'Synchrotron Light' is an interactive and detailed introduction to the physics and technology of the generation of coherent radiation from accelerators as well as to its widespread high-tech applications in science, medicine and engineering. The topics covered are the interaction of light and matter, the technology of synchrotron light sources, spectroscopy, imaging, scattering and diffraction of X-rays, and applications to materials science, biology, biochemistry, medicine, chemistry, food and pharmaceutical technology. All synchrotron light facilities are introduced with their home-page addresses. 'Synchrotron Light' provides an instructive and comprehensive multimedia learning tool for students, experienced practitioners and novices wishing to apply synchrotron radiation in their future work. Its multiple-entry points permit an easy exploration of the CD-Rom according to the users knowledge and interest. 2-D and 3-D animations and virtual reconstruction with computer-generated images guide visitors into the scientific and technical world of a synchrotron and into the applications of synchrotron radiation. This bilingual (English and French) CD-Rom can be used for self-teaching and in courses at various levels in physics, chemistry, engineering, and biology. (author)

  1. Critical evaluation of the pulsed laser method for single event effects testing and fundamental studies

    International Nuclear Information System (INIS)

    Melinger, J.S.; Buchner, S.; McMorrow, D.; Stapor, W.J.; Weatherford, T.R.; Campbell, A.B.; Eisen, H.

    1994-01-01

    In this paper the authors present an evaluation of the pulsed laser as a technique for single events effects (SEE) testing. They explore in detail the important optical effects, such as laser beam propagation, surface reflection, and linear and nonlinear absorption, which determine the nature of laser-generated charge tracks in semiconductor materials. While there are differences in the structure of laser- and ion-generated charge tracks, they show that in many cases the pulsed laser remains an invaluable tool for SEE testing. Indeed, for several SEE applications, they show that the pulsed laser method represents a more practical approach than conventional accelerator-based methods

  2. Integrated single grating compressor for variable pulse front tilt in simultaneously spatially and temporally focused systems.

    Science.gov (United States)

    Block, Erica; Thomas, Jens; Durfee, Charles; Squier, Jeff

    2014-12-15

    A Ti:Al(3)O(2) multipass chirped pulse amplification system is outfitted with a single-grating, simultaneous spatial and temporal focusing (SSTF) compressor platform. For the first time, this novel design has the ability to easily vary the beam aspect ratio of an SSTF beam, and thus the degree of pulse-front tilt at focus, while maintaining a net zero-dispersion system. Accessible variation of pulse front tilt gives full spatiotemporal control over the intensity distribution at the focus and could lead to better understanding of effects such as nonreciprocal writing and SSTF-material interactions.

  3. Measurement of flow fluctuations in single longitudinal mode pulsed ...

    Indian Academy of Sciences (India)

    2014-02-12

    Feb 12, 2014 ... The single mode dye laser is a very useful tool for high-resolution spectroscopy, resonance ionization spec- troscopy (RIS), coherent control etc. For many spectroscopic applications it is however necessary to have a control over the emission linewidth of the dye laser. The frequency- stabilized tunable laser ...

  4. Role of third-order dispersion in chirped Airy pulse propagation in single-mode fibers

    Science.gov (United States)

    Cai, Wangyang; Wang, Lei; Wen, Shuangchun

    2018-04-01

    The dynamic propagation of the initial chirped Airy pulse in single-mode fibers is studied numerically, special attention being paid to the role of the third-order dispersion (TOD). It is shown that for the positive TOD, the Airy pulse experiences inversion irrespective of the sign of initial chirp. The role of TOD in the dynamic propagation of the initial chirped Airy pulse depends on the combined sign of the group-velocity dispersion (GVD) and the initial chirp. If the GVD and chirp have the opposite signs, the chirped Airy pulse compresses first and passes through a breakdown area, then reconstructs a new Airy pattern with opposite acceleration, with the breakdown area becoming small and the main peak of the new Airy pattern becoming asymmetric with an oscillatory structure due to the positive TOD. If the GVD and chirp have the same signs, the finite-energy Airy pulse compresses to a focal point and then inverses its acceleration, in the case of positive TOD, the distance to the focal point becoming smaller. At zero-dispersion point, the finite-energy Airy pulse inverses to the opposite acceleration at a focal point, with the tight-focusing effect being reduced by initial chirp. Under the effect of negative TOD, the initial chirped Airy pulse disperses and the lobes split. In addition, in the anomalous dispersion region, for strong nonlinearity, the initial chirped Airy pulse splits and enters a soliton shedding regime.

  5. Physics and technology of tunable pulsed single longitudinal mode ...

    Indian Academy of Sciences (India)

    Figure 8. Principle of two-mode operation. Figure 9. Amplifier efficiency vs. wavelength. Experimentally observed wavelength change is 2.5 pm/◦C = 2.39 GHz/◦C at. 560 nm. It was observed that if the dye temperature was stabilized there was no transition from single-mode to twin-mode over an hour operation. Change in ...

  6. Synchrotron radiation

    International Nuclear Information System (INIS)

    Helliwell, J.R.; Walker, R.P.

    1985-01-01

    A detailed account of the research work associated with the Synchrotron Radiation Source at Daresbury Laboratory, United Kingdom, in 1984/85, is presented in the Appendix to the Laboratory's Annual Report. (U.K.)

  7. Application of synchrotron radiation to analyze the precipitation in ODS materials before irradiation in Fe-9%Cr single grain of powder and consolidated Fe-18%Cr

    Energy Technology Data Exchange (ETDEWEB)

    Bechade, J.-L., E-mail: jean-luc.bechade@cea.fr [CEA, DEN, Service de Recherches Metallurgiques Appliquees, 91191 Gif-sur-Yvette (France); Menut, D., E-mail: denis.menut@cea.fr [CEA, DEN, Service de Recherches Metallurgiques Appliquees, 91191 Gif-sur-Yvette (France); Lescoat, M.-L., E-mail: marie-laure.lescoat@cea.fr [CEA, DEN, Service de Recherches Metallurgiques Appliquees, 91191 Gif-sur-Yvette (France); Sitaud, B., E-mail: bruno.sitaud@synchrotron-soleil.fr [Synchrotron SOLEIL, Division Experiences, Ligne de MARS, L' Orme des Merisiers, Saint Aubin BP48, 91 192 Gif-sur-Yvette Cedex (France); Schlutig, S., E-mail: sandrine.schlutig@synchrotron-soleil.fr [Synchrotron SOLEIL, Division Experiences, Ligne de MARS, L' Orme des Merisiers, Saint Aubin BP48, 91 192 Gif-sur-Yvette Cedex (France); Solari, P.L., E-mail: pier-lorenzo.solari@synchrotron-soleil.fr [Synchrotron SOLEIL, Division Experiences, Ligne de MARS, L' Orme des Merisiers, Saint Aubin BP48, 91 192 Gif-sur-Yvette Cedex (France); Llorens, I., E-mail: isabelle.llorens@synchrotron-soleil.fr [Synchrotron SOLEIL, Division Experiences, Ligne de MARS, L' Orme des Merisiers, Saint Aubin BP48, 91 192 Gif-sur-Yvette Cedex (France); Hermange, H., E-mail: herve.hermange@synchrotron-soleil.fr [Synchrotron SOLEIL, Division Experiences, Ligne de MARS, L' Orme des Merisiers, Saint Aubin BP48, 91 192 Gif-sur-Yvette Cedex (France); and others

    2012-09-15

    Oxide Dispersion Strengthened (ODS) materials are candidates for structural components of GEN IV and fusion reactors. These materials are reinforced by nano-oxides (size of the smallest <3 nm) and the excellent mechanical properties obtained with such materials have to be kept in service. The aim of this paper is to present the capabilities of the synchrotron radiation to finely characterize the dispersion of second phases in ODS steels (Fe-9%Cr single grain of powder and consolidated Fe-18%Cr) and to study the precipitation mechanisms. This paper illustrates the results from first analyses performed on various unirradiated ODS steels elaborated at CEA using X-ray diffraction (XRD) and X-ray absorption spectroscopy (XAS) at the Multi-Analysis on Radioactive Sample (MARS) beamline of the SOLEIL synchrotron facility. The complementarities of both techniques, XRD and XAS, especially well appropriated to structural and local environment analyses for nano particles are presented. Results obtained with synchrotron radiation are also enriched by comparison with Transmission Electron Microscopy (TEM) observations performed on similar samples.

  8. Synchrotron radiation

    International Nuclear Information System (INIS)

    Norman, D.; Walker, R.P.; Durham, P.J.; Ridley, P.A.

    1986-01-01

    The paper on synchrotron radiation is the appendix to the Daresbury (United Kingdom) annual report, 1985/86. The bulk of the volume is made up of the progress reports for the work carried out during the year under review using the Synchrotron Radiation Source (SRS) at Daresbury. The Appendix also contains: the scientific programmes at the the SRS, progress on beamlines, instrumentation and computing developments, and activities connected with accelerator development. (U.K.)

  9. Synchrotron radiation

    International Nuclear Information System (INIS)

    Poole, M.W.; Lea, K.R.

    1982-01-01

    A report is given on the work involving the Synchrotron Radiation Division of the Daresbury Laboratory during the period January 1981 - March 1982. Development of the source, beamlines and experimental stations is described. Progress reports from individual investigators are presented which reveal the general diversity and interdisciplinary nature of the research which benefits from access to synchrotron radiation and the associated facilities. Information is given on the organisation of the Division and publications written by the staff are listed. (U.K.)

  10. Dynamics of a Birth-Pulse Single-Species Model with Restricted Toxin Input and Pulse Harvesting

    Directory of Open Access Journals (Sweden)

    Yi Ma

    2010-01-01

    Full Text Available We consider a birth-pulses single-species model with restricted toxin input and pulse harvesting in a polluted environment. Pollution accumulates as a slowly decaying stock and is assumed to affect the growth of the renewable resource population. Firstly, by using the discrete dynamical system determined by the stroboscopic map, we obtain an exact 1-period solution of system whose birth function is Ricker function or Beverton-Holt function and obtain the threshold conditions for their stability. Furthermore, we show that the timing of harvesting has a strong impact on the maximum annual sustainable yield. The best timing of harvesting is immediately after the birth pulses. Finally, we investigate the effect of the amount of toxin input on the stable resource population size. We find that when the birth rate is comparatively lower, the population size is decreasing with the increase of toxin input; that when the birth rate is high, the population size may begin to rise and then drop with the increase of toxin input.

  11. SYNCHROTRON RADIATION SOURCES

    Energy Technology Data Exchange (ETDEWEB)

    HULBERT,S.L.; WILLIAMS,G.P.

    1998-07-01

    Synchrotron radiation is a very bright, broadband, polarized, pulsed source of light extending from the infrared to the x-ray region. It is an extremely important source of Vacuum Ultraviolet radiation. Brightness is defined as flux per unit area per unit solid angle and is normally a more important quantity than flux alone particularly in throughput limited applications which include those in which monochromators are used. It is well known from classical theory of electricity and magnetism that accelerating charges emit electromagnetic radiation. In the case of synchrotron radiation, relativistic electrons are accelerated in a circular orbit and emit electromagnetic radiation in a broad spectral range. The visible portion of this spectrum was first observed on April 24, 1947 at General Electric's Schenectady facility by Floyd Haber, a machinist working with the synchrotron team, although the first theoretical predictions were by Lienard in the latter part of the 1800's. An excellent early history with references was presented by Blewett and a history covering the development of the utilization of synchrotron radiation was presented by Hartman. Synchrotron radiation covers the entire electromagnetic spectrum from the infrared region through the visible, ultraviolet, and into the x-ray region up to energies of many 10's of kilovolts. If the charged particles are of low mass, such as electrons, and if they are traveling relativistically, the emitted radiation is very intense and highly collimated, with opening angles of the order of 1 milliradian. In electron storage rings there are three possible sources of synchrotron radiation; dipole (bending) magnets; wigglers, which act like a sequence of bending magnets with alternating polarities; and undulators, which are also multi-period alternating magnet systems but in which the beam deflections are small resulting in coherent interference of the emitted light.

  12. Technology and engineering aspects of high power pulsed single longitudinal mode dye lasers

    Science.gov (United States)

    Rawat, V. S.; Mukherjee, Jaya; Gantayet, L. M.

    2015-09-01

    Tunable single mode pulsed dye lasers are capable of generating optical radiations in the visible range having very small bandwidths (transform limited), high average power (a few kW) at a high pulse repetition rate (a few tens of kHz), small beam divergence and relatively higher efficiencies. These dye lasers are generally utilized laser dyes dissolved in solvents such as water, heavy water, ethanol, methanol, etc. to provide a rapidly flowing gain medium. The dye laser is a versatile tool, which can lase either in the continuous wave (CW) or in the pulsed mode with pulse duration as small as a few tens of femtoseconds. In this review, we have examined the several cavity designs, various types of gain mediums and numerous types of dye cell geometries for obtaining the single longitudinal mode pulsed dye laser. Different types of cavity configuration, such as very short cavity, short cavity with frequency selective element and relatively longer cavity with multiple frequency selective elements were reviewed. These single mode lasers have been pumped by all kinds of pumping sources such as flash lamps, Excimer, Nitrogen, Ruby, Nd:YAG, Copper Bromide and Copper Vapor Lasers. The single mode dye lasers are either pumped transversely or longitudinally to the resonator axis. The pulse repletion rate of these pump lasers were ranging from a few Hz to a few tens of kHz. Physics technology and engineering aspects of tuning mechanism, mode hop free scanning and dye cell designs are also presented in this review. Tuning of a single mode dye laser with a resolution of a few MHz per step is a technologically challenging task, which is discussed here.

  13. Excitation of random intense single-cycle light-pulse chains in optical fiber

    International Nuclear Information System (INIS)

    Ding, Y C; Zhang, F L; Gao, J B; Chen, Z Y; Lin, C Y; Yu, M Y

    2014-01-01

    Excitation of intense periodic single-cycle light pulses in a stochastic background arising from continuous wave stimulated Brillouin scattering (SBS) in a long optical fiber with weak optical feedback is found experimentally and modeled theoretically. Such intense light-pulse chains occur randomly and the optical feedback is a requirement for their excitation. The probability of these forms, among the large number of experimental output signals with identifiable waveforms, appearing is only about 3%, with the remainder exhibiting regular SBS characteristics. It is also found that pulses with low period numbers appear more frequently and the probability distribution for their occurrence in terms of the pulse power is roughly L-shaped, like that for rogue waves. The results from a three-wave-coupling model for SBS including feedback phase control agree well qualitatively with the observed phenomena. (paper)

  14. All-normal-dispersion fiber laser with NALM: power scalability of the single-pulse regime

    Science.gov (United States)

    Gao, Gan; Zhang, Haitao; Li, Yuhe; Deng, Decai

    2018-03-01

    We investigate the average power scalability of all-normal-dispersion fiber integrated lasers with a nonlinear amplifying loop. This laser generates 34 ps pulses at a repetition of 8 MHz and spectral width of 30 nm when increased to the highest power. The laser operates on a single-pulse train regime and can be de-chirped as short as 200 fs. The 60 mW output power which can be maintained while operating with low Raman effect is the highest average power achieved for this type of laser in the sub-200 fs regime. The laser becomes unstable due to the strengthening of the Raman–Stokes pulse. Output pulses show great stability in testing.

  15. Pulse-height defect in single-crystal CVD diamond detectors

    Energy Technology Data Exchange (ETDEWEB)

    Beliuskina, O.; Imai, N. [The University of Tokyo, Center for Nuclear Study, Wako, Saitama (Japan); Strekalovsky, A.O.; Aleksandrov, A.A.; Aleksandrova, I.A.; Ilich, S.; Kamanin, D.V.; Knyazheva, G.N.; Kuznetsova, E.A.; Mishinsky, G.V.; Pyatkov, Yu.V.; Strekalovsky, O.V.; Zhuchko, V.E. [JINR, Flerov Laboratory of Nuclear Reactions, Dubna, Moscow Region (Russian Federation); Devaraja, H.M. [Manipal University, Manipal Centre for Natural Sciences, Manipal, Karnataka (India); Heinz, C. [II. Physikalisches Institut, Justus-Liebig-Universitaet Giessen, Giessen (Germany); Heinz, S. [II. Physikalisches Institut, Justus-Liebig-Universitaet Giessen, Giessen (Germany); GSI Helmholtzzentrum fuer Schwerionenforschung, Darmstadt (Germany); Hofmann, S.; Kis, M.; Kozhuharov, C.; Maurer, J.; Traeger, M. [GSI Helmholtzzentrum fuer Schwerionenforschung, Darmstadt (Germany); Pomorski, M. [CEA, LIST, Diamond Sensor Laboratory, CEA/Saclay, Gif-sur-Yvette (France)

    2017-02-15

    The pulse-height versus deposited energy response of a single-crystal chemical vapor deposition (scCVD) diamond detector was measured for ions of Ti, Cu, Nb, Ag, Xe, Au, and of fission fragments of {sup 252} Cf at different energies. For the fission fragments, data were also measured at different electric field strengths of the detector. Heavy ions have a significant pulse-height defect in CVD diamond material, which increases with increasing energy of the ions. It also depends on the electrical field strength applied at the detector. The measured pulse-height defects were explained in the framework of recombination models. Calibration methods known from silicon detectors were modified and applied. A comparison with data for the pulse-height defect in silicon detectors was performed. (orig.)

  16. Experimental study on the single event effects in pulse width modulators by laser testing

    International Nuclear Information System (INIS)

    Zhao Wen; Guo Xiaoqiang; Chen Wei; Guo Hongxia; Lin Dongsheng; Luo Yinhong; Ding Lili; Wang Yuanming; Wang Hanning

    2015-01-01

    This paper presents single event effect (SEE) characteristics of UC1845AJ pulse width modulators (PWMs) by laser testing. In combination with analysis to map PWM circuitry in the microchip dies, the typical SEE response waveforms for laser pulses located in different circuit blocks of UC1845AJ are obtained and the SEE mechanisms are analyzed. The laser SEE test results show that there are some differences in the SEE mechanisms of different circuit blocks, and phase shifts or changes in the duty cycles of few output pulses are the main SEE behaviors for UC1845AJ. In addition, a new SEE behavior which manifests as changes in the duty cycles of many output pulses is revealed. This means that an SEE hardened design should be considered. (paper)

  17. Coherent synchrotron radiation

    International Nuclear Information System (INIS)

    Agoh, Tomonori

    2006-01-01

    This article presents basic properties of coherent synchrotron radiation (CSR) with numerical examples and introduces the reader to important aspects of CSR in future accelerators with short bunches. We show interesting features of the single bunch instability due to CSR in storage rings and discuss the longitudinal CSR field via the impedance representation. (author)

  18. Sagittal focusing of synchrotron radiation on the walls of a longitudinal hole drilled into a single-crystal monochromator

    Czech Academy of Sciences Publication Activity Database

    Artemiev, Nikolai; Hrdý, Jaromír; Peredkov, S.; Artemev, A.; Freud, A.; Tucoulou, R.

    2001-01-01

    Roč. 8, - (2001), s. 1207-1213 ISSN 0909-0495. [Syncrotron Radiation Instrumentation. Madison, 22.08.2001-24.08.2001] R&D Projects: GA AV ČR IAA1010104; GA MPO PZ-CH/22; GA MŠk OK 305 Institutional research plan: CEZ:AV0Z1010914 Keywords : focusing of synchrotron radiation Subject RIV: BH - Optics, Masers, Lasers Impact factor: 1.519, year: 2001

  19. Simultaneous SU(2) rotations on multiple quantum dot exciton qubits using a single shaped pulse

    Science.gov (United States)

    Mathew, Reuble; Yang, Hong Yi Shi; Hall, Kimberley C.

    2015-10-01

    Recent experimental demonstration of a parallel (π ,2 π ) single qubit rotation on excitons in two distant quantum dots [Nano Lett. 13, 4666 (2013), 10.1021/nl4018176] is extended in numerical simulations to the design of pulses for more general quantum state control, demonstrating the feasibility of full SU(2) rotations of each exciton qubit. Our results show that simultaneous high-fidelity quantum control is achievable within the experimentally accessible parameter space for commercial Fourier-domain pulse shaping systems. The identification of a threshold of distinguishability for the two quantum dots (QDs) for achieving high-fidelity parallel rotations, corresponding to a difference in transition energies of ˜0.25 meV , points to the possibility of controlling more than 10 QDs with a single shaped optical pulse.

  20. Two-color monochromatic x-ray imaging with a single short-pulse laser

    Science.gov (United States)

    Sawada, H.; Daykin, T.; McLean, H. S.; Chen, H.; Patel, P. K.; Ping, Y.; Pérez, F.

    2017-06-01

    Simultaneous monochromatic crystal imaging at 4.5 and 8.0 keV with x-rays produced by a single short-pulse laser is presented. A layered target consisting of thin foils of titanium and copper glued together is irradiated by the 50 TW Leopard short-pulse laser housed at the Nevada Terawatt Facility. Laser-accelerated MeV fast electrons transmitting through the target induce Kα fluorescence from both foils. Two energy-selective curved crystals in the imaging diagnostic form separate monochromatic images on a single imaging detector. The experiment demonstrates simultaneous two-color monochromatic imaging of the foils on a single detector as well as Kα x-ray production at two different photon energies with a single laser beam. Application of the diagnostic technique to x-ray radiography of a high density plasma is also presented.

  1. Enhanced activity of deoxycytidine kinase after pulsed low dose rate and single dose gamma irradiation

    NARCIS (Netherlands)

    Sigmond, J.; Haveman, J.; Kreder, N. Castro; Loves, W. J.; van Bree, C.; Franken, N. A.; Peters, G. J.

    2006-01-01

    In both pulsed low dose rate (LDR) and single high dose radiation schedules, gemcitabine pretreatment sensitizes tumor cells to radiation. These radiosensitizing effects could be the result of decreased DNA repair. In this study, the effect of irradiation on the deoxycytidine kinase (dCK) needed for

  2. Visual CRO display of pulse height distribution including discriminator setting for a single channel X-ray analyser

    International Nuclear Information System (INIS)

    Shaw, S.E.

    1979-01-01

    An outline for a simple pulse spectroscope which attaches to a standard laboratory CRO is presented. The peak amplitude voltage of each pulse from the linear amplifier of a single channel X-ray analyser is stored for the duration of one oscilloscope trace. For each amplifier pulse, input from the discriminator is tested and if these is coincidence of pulses the oscilloscope beam is blanked for approximately the first 2 cm of its traverse across the screen. Repetition of pulses forms a pulse height distribution with a rectangular dark area marking the position of the discriminator window. (author)

  3. Cost-effective design of a concurrent photoacoustic-ultrasound microscope using single laser pulses

    Science.gov (United States)

    Wu, Wen-Shao; Liu, Wei-Wen; Li, Pai-Chi

    2016-03-01

    A method for concurrent photoacoustic (PA) and ultrasound (US) imaging with single laser pulses was previously demonstrated. An optical-absorbing multilayer film that can generate a US pulse based on the thermoelastic effect is used. With such a film, the generated US can be adjusted so that it does not overlap with the spectrum of the PA signal generated by the light transmitting through the layer. Thus, the US signal and the PA signal can be generated and separated by using a single laser pulse with spectral filtering. In this study, we continue with the same concurrent imaging approach and propose a cost-effective and portable design. The design consists of a pulsed laser diode with the repetition rate up to 25 kHz and energy of 2 μJ/pulse. A multilayer film is employed to generate narrow band US signals under laser excitation for US imaging. With simple spectral filtering, the PA signals and the US signals can be separated. With optical resolution, the system has a theoretical lateral resolution of 2 μm in PA imaging and 200 μm in US imaging. One of the applications of the proposed microscope is for tumor biology, where angiogenesis is an essential topic for understanding tumor growth and tumor metastasis. We will demonstrate performance of the proposed system by imaging vasculature networks.

  4. Timing Solution and Single-pulse Properties for Eight Rotating Radio Transients

    Energy Technology Data Exchange (ETDEWEB)

    Cui, B.-Y.; McLaughlin, M. A. [Department of Physics and Astronomy West Virginia University Morgantown, WV 26506 (United States); Boyles, J. [Department of Physics and Astronomy West Kentucky University Bowling Green, KY 42101 (United States); Palliyaguru, N. [Physics and Astronomy Department Texas Tech University Lubbock, TX 79409-1051 (United States)

    2017-05-01

    Rotating radio transients (RRATs), loosely defined as objects that are discovered through only their single pulses, are sporadic pulsars that have a wide range of emission properties. For many of them, we must measure their periods and determine timing solutions relying on the timing of their individual pulses, while some of the less sporadic RRATs can be timed by using folding techniques as we do for other pulsars. Here, based on Parkes and Green Bank Telescope (GBT) observations, we introduce our results on eight RRATs including their timing-derived rotation parameters, positions, and dispersion measures (DMs), along with a comparison of the spin-down properties of RRATs and normal pulsars. Using data for 24 RRATs, we find that their period derivatives are generally larger than those of normal pulsars, independent of any intrinsic correlation with period, indicating that RRATs’ highly sporadic emission may be associated with intrinsically larger magnetic fields. We carry out Lomb–Scargle tests to search for periodicities in RRATs’ pulse detection times with long timescales. Periodicities are detected for all targets, with significant candidates of roughly 3.4 hr for PSR J1623−0841 and 0.7 hr for PSR J1839−0141. We also analyze their single-pulse amplitude distributions, finding that log-normal distributions provide the best fits, as is the case for most pulsars. However, several RRATs exhibit power-law tails, as seen for pulsars emitting giant pulses. This, along with consideration of the selection effects against the detection of weak pulses, imply that RRAT pulses generally represent the tail of a normal intensity distribution.

  5. Timing Solution and Single-pulse Properties for Eight Rotating Radio Transients

    Science.gov (United States)

    Cui, B.-Y.; Boyles, J.; McLaughlin, M. A.; Palliyaguru, N.

    2017-05-01

    Rotating radio transients (RRATs), loosely defined as objects that are discovered through only their single pulses, are sporadic pulsars that have a wide range of emission properties. For many of them, we must measure their periods and determine timing solutions relying on the timing of their individual pulses, while some of the less sporadic RRATs can be timed by using folding techniques as we do for other pulsars. Here, based on Parkes and Green Bank Telescope (GBT) observations, we introduce our results on eight RRATs including their timing-derived rotation parameters, positions, and dispersion measures (DMs), along with a comparison of the spin-down properties of RRATs and normal pulsars. Using data for 24 RRATs, we find that their period derivatives are generally larger than those of normal pulsars, independent of any intrinsic correlation with period, indicating that RRATs’ highly sporadic emission may be associated with intrinsically larger magnetic fields. We carry out Lomb-Scargle tests to search for periodicities in RRATs’ pulse detection times with long timescales. Periodicities are detected for all targets, with significant candidates of roughly 3.4 hr for PSR J1623-0841 and 0.7 hr for PSR J1839-0141. We also analyze their single-pulse amplitude distributions, finding that log-normal distributions provide the best fits, as is the case for most pulsars. However, several RRATs exhibit power-law tails, as seen for pulsars emitting giant pulses. This, along with consideration of the selection effects against the detection of weak pulses, imply that RRAT pulses generally represent the tail of a normal intensity distribution.

  6. A method for measuring the time structure of synchrotron x-ray beams

    International Nuclear Information System (INIS)

    Moses, W.W.; Derenzo, S.E.

    1989-08-01

    We describe a method employing a plastic scintillator coupled to a fast photomultiplier tube to generate a timing pulse from the x-ray bursts emitted from a synchrotron radiation source. This technique is useful for performing synchrotron experiments where detailed knowledge of the timing distribution is necessary, such as time resolved spectroscopy or fluorescence lifetime experiments. By digitizing the time difference between the timing signal generated on one beam crossing with the timing signal generated on the next beam crossing, the time structure of a synchrotron beam can be analyzed. Using this technique, we have investigated the single bunch time structure at the National Synchrotron Light Source (NSLS) during pilot runs in January, 1989, and found that the majority of the beam (96%) is contained in one rf bucket, while the remainder of the beam (4%) is contained in satellite rf buckets preceeding and following the main rf bucket by 19 ns. 1 ref., 4 figs

  7. Panel backs next-generation synchrotron

    CERN Multimedia

    Service, R F

    1999-01-01

    A key federal panel recommended continued research into development of a fourth-generation synchrotron. It would be capable of creating x-ray pulses billions of times more intense than current designs (1 page).

  8. Linearly frequency-modulated pulsed single-frequency fiber laser at 1083 nm.

    Science.gov (United States)

    Zhang, Yuanfei; Yang, Changsheng; Li, Can; Feng, Zhouming; Xu, Shanhui; Deng, Huaqiu; Yang, Zhongmin

    2016-02-22

    A linearly frequency-modulated, actively Q-switched, single-frequency ring fiber laser based on injection seeding from an ultra-short cavity is demonstrated at 1083 nm. A piezoelectric transducer is employed to obtain linearly frequency-modulating performance and over 1.05 GHz frequency-tuning range is achieved with a modulating frequency reaching tens of kilohertz. A maximum peak power of the stable output pulse is over 3.83 W during frequency-modulating process. This type of pulsed fiber laser provides a promising candidate for coherent LIDAR in the measurement of thermosphere.

  9. Performance characteristics of an excimer laser (XeCl) with single-stage magnetic pulse compression

    Science.gov (United States)

    Varshnay, N. K.; Singh, A.; Benerji, N. S.

    2017-02-01

    Performance characteristics of an excimer laser (XeCl) with single-stage magnetic pulse compression suitable for material processing applications are presented here. The laser incorporates in-built compact gas circulation and gas cooling to ensure fresh gas mixture between the electrodes for repetitive operation. A magnetically coupled tangential blower is used for gas circulation inside the laser chamber for repetitive operation. The exciter consists of C-C energy transfer circuit and thyratron is used as a high-voltage main switch with single-stage magnetic pulse compression (MPC) between thyratron and the laser electrodes. Low inductance of the laser head and uniform and intense pre-ionization are the main features of the electric circuit used in the laser. A 250 ns rise time voltage pulse was compressed to 100 ns duration with a single-stage magnetic pulse compressor using Ni-Zn ferrite cores. The laser can generate about 150 mJ at ˜100 Hz rep-rate reliably from a discharge volume of 100 cm 3. 2D spatial laser beam profile generated is presented here. The profile shows that the laser beam is completely filled with flat-top which is suitable for material processing applications. The SEM image of the microhole generated on copper target is presented here.

  10. Pulsed single-photon spectrometer by frequency-to-time mapping using chirped fiber Bragg gratings.

    Science.gov (United States)

    Davis, Alex O C; Saulnier, Paul M; Karpiński, Michał; Smith, Brian J

    2017-05-29

    A fiber-integrated spectrometer for single-photon pulses outside the telecommunications wavelength range based upon frequency-to-time mapping, implemented by chromatic group delay dispersion (GDD), and precise temporally-resolved single-photon counting, is presented. A chirped fiber Bragg grating provides low-loss GDD, mapping the frequency distribution of an input pulse onto the temporal envelope of the output pulse. Time-resolved detection with fast single-photon-counting modules enables monitoring of a wavelength range from 825 nm to 835 nm with nearly uniform efficiency at 55 pm resolution (24 GHz at 830 nm). To demonstrate the versatility of this technique, spectral interference of heralded single photons and the joint spectral intensity distribution of a photon-pair source are measured. This approach to single-photon-level spectral measurements provides a route to realize applications of time-frequency quantum optics at visible and near-infrared wavelengths, where multiple spectral channels must be simultaneously monitored.

  11. Single-electron pulse-height spectra in thin-gap parallel-plate chambers

    CERN Document Server

    Fonte, Paulo J R; Peskov, Vladimir; Policarpo, Armando

    1999-01-01

    Single-electron pulse-height spectra were measured in 0.6 and 1.2 mm parallel-plate chambers developed for the TOF system of the ALICE /LHC-HI experiment. Mixtures of Ar with ethane, isobutane, and SF/sub 6/ were studied. The observed spectrum shows a clear peak for all gases, suggesting efficient single-electron detection in thin parallel-plate structures. The pulse-height spectrum can be described by the weighted sum of an exponential and a Polya distribution, the Polya contribution becoming more important at higher gains. Additionally, it was found that the maximum gain, above 10/sup 6/, is limited by the appearance of streamers and depends weakly on the gas composition. The suitability of each mixture for single-electron detection is also quantitatively assessed. (8 refs).

  12. Time-resolved spectroscopy in synchrotron radiation

    International Nuclear Information System (INIS)

    Rehn, V.; Stanford Univ., CA

    1980-01-01

    Synchrotron radiation (SR) from large-diameter storage rings has intrinsic time structure which facilitates time-resolved measurements form milliseconds to picoseconds and possibly below. The scientific importance of time-resolved measurements is steadily increasing as more and better techniques are discovered and applied to a wider variety of scientific problems. This paper presents a discussion of the importance of various parameters of the SR facility in providing for time-resolved spectroscopy experiments, including the role of beam-line optical design parameters. Special emphasis is placed on the requirements of extremely fast time-resolved experiments with which the effects of atomic vibrational or relaxation motion may be studied. Before discussing the state-of-the-art timing experiments, we review several types of time-resolved measurements which have now become routine: nanosecond-range fluorescence decay times, time-resolved emission and excitation spectroscopies, and various time-of-flight applications. These techniques all depend on a short SR pulse length and a long interpulse period, such as is provided by a large-diameter ring operating in a single-bunch mode. In most cases, the pulse shape and even the stability of the pulse shape is relatively unimportant as long as the pulse length is smaller than the risetime of the detection apparatus, typically 1 to 2 ns. For time resolution smaller than 1 ns, the requirements on the pulse shape become more stringent. (orig./FKS)

  13. Tandems as injectors for synchrotrons

    International Nuclear Information System (INIS)

    Ruggiero, A.G.

    1993-01-01

    This is a review on the use of tandem electrostatic accelerators for injection and fitting of synchrotrons to accelerate intense beams of heavy ions to relativistic energies. The paper emphasizes the need of operating the tandems in pulsed mode for this application. It has been experimentally demonstrated that at present this type of accelerator still provides the most reliable and best performance. (orig.)

  14. Ultra-fast ballistic magnetization reversal triggered by a single magnetic field pulse

    Energy Technology Data Exchange (ETDEWEB)

    Horley, Paul P; Gonzalez Hernandez, Jesus [Centro de Investigacion en Materiales Avanzados S.C., Chihuahua/Monterrey, Av. Miguel de Cervantes 120, 31109 Chihuahua, Chihuahua (Mexico); Vieira, Vitor R; Dugaev, Vitalii K [Centro de Fisica das Interaccoes Fundamentais, Instituto Superior Tecnico, Universidade Tecnica de Lisboa, Avenida Rovisco Pais, 1049-001 Lisbon (Portugal); Gorley, Peter [Department of Physics, Yuri Fedkovych Chernivtsi National University, 2 Kotsyubynsky Street, 58012 Chernivtsi (Ukraine); Barnas, Jozef, E-mail: paul.horley@cimav.edu.m [Institute of Molecular Physics, Polish Academy of Sciences, ul. Smoluchowskiego 17, 60-179 Poznan (Poland)

    2009-12-21

    Performance of devices such as magnetic random access memories crucially depends on magnetic switching time. By numerical simulations we show that ultra-fast (in the sub-nanosecond range) magnetic reversal in nanoparticles can be achieved with a single pulse of magnetic field oriented at some specific angles with respect to the magnetic moment. These angles form the areas of ballistic reversal (with no magnetization ringing). We show that the size of these areas increases with decreasing pulse duration, which allows reaching of the sub-nanosecond reversal for a pulse duration of the order of dozen(s) of ps. When changing the magnetic field, the areas of ballistic reversal move along the equator of the unitary sphere, and eventually merge with each other. For appropriate choice of the azimuthal angle, one can reach magnetic reversal along a trajectory located in or out of the easy plane.

  15. Strengthening and damping of synchrotron oscillations

    International Nuclear Information System (INIS)

    Taratin, A.M.

    2001-01-01

    Resonance strengthening and damping of synchrotron oscillations of collider bunch halo particles was studied by simulation. It was shown that the strengthening of particle synchrotron oscillations can be highly efficient with using a resonance pulse sequence. The resonance damping of particle synchrotron oscillations is only possible when the inverse population of the accelerated bunch halo is realized. Resonance method of synchrotron oscillation strengthening can be used for the extraction of beam halo particles with a bent crystal to improve the background conditions for colliding beam experiments and to fulfill simultaneously some fixed target experiments

  16. Self-organization of single filaments and diffusive plasmas during a single pulse in dielectric-barrier discharges

    International Nuclear Information System (INIS)

    Babaeva, Natalia Yu; Kushner, Mark J

    2014-01-01

    Self-organization of filaments in dielectric-barrier discharges (DBDs) probably has many origins. However, the dominant cause is proposed to be the accumulation of charge on the surfaces of the bounding dielectrics that reinforces successive discharge pulses to occur at the same locations. A secondary cause is the electrostatic repulsion of individual plasma filaments. Self-organization typically develops over many discharge pulses. In this paper, we discuss the results of a computational investigation of plasma filaments in overvoltage DBDs that, under select conditions, display self-organized patterns (SOPs) of plasma density during a single discharge pulse. (Overvoltage refers to the rapid application of a voltage in excess of the quasi-dc breakdown voltage.) The origin of the SOPs is a synergistic relationship between the speed of the surface-ionization waves that propagate along each dielectric and the rate at which avalanche occurs across the gap. For our test conditions, SOPs were not observed at lower voltages and gradually formed at higher voltages. The same conditions that result in SOPs, i.e. the application of an overvoltage, also produce more diffuse discharges. A transition from a single narrow filament to a more diffuse structure was observed as overvoltage was approached. The sensitivity of SOPs to the orientation and permittivity of the bounding dielectrics is discussed. (paper)

  17. Microscopic heat pulse-induced calcium dynamics in single WI-38 fibroblasts.

    Science.gov (United States)

    Itoh, Hideki; Oyama, Kotaro; Suzuki, Madoka; Ishiwata, Shin'ichi

    2014-01-01

    Temperature-sensitive Ca(2+) dynamics occur primarily through transient receptor potential channels, but also by means of Ca(2+) channels and pumps on the endoplasmic reticulum membrane. As such, cytoplasmic Ca(2+) concentration ([Ca(2+)]cyt) is re-equilibrated by changes in ambient temperature. The present study investigated the effects of heat pulses (heating duration: 2 s or 150 s) on [Ca(2+)]cyt in single WI-38 fibroblasts, which are considered as normal cells. We found that Ca(2+) burst occurred immediately after short (2 s) heat pulse, which is similar to our previous report on HeLa cells, but with less thermosensitivity. The heat pulses originated from a focused 1455-nm infrared laser light were applied in the vicinity of cells under the optical microscope. Ca(2+) bursts induced by the heat pulse were suppressed by treating cells with inhibitors for sarco/endoplasmic reticulum Ca(2+) ATPase (SERCA) or inositol trisphosphate receptor (IP3R). Long (150 s) heat pulses also induced Ca(2+) bursts after the onset of heating and immediately after re-cooling. Cells were more thermosensitive at physiological (37°C) than at room (25°C) temperature; however, at 37°C, cells were responsive at a higher temperature (ambient temperature+heat pulse). These results strongly suggest that the heat pulse-induced Ca(2+) burst is caused by a transient imbalance in Ca(2+) flow between SERCA and IP3R, and offer a potential new method for thermally controlling Ca(2+)-regulated cellular functions.

  18. The tensile effect on crack formation in single crystal silicon irradiated by intense pulsed ion beam

    Science.gov (United States)

    Liang, Guoying; Shen, Jie; Zhang, Jie; Zhong, Haowen; Cui, Xiaojun; Yan, Sha; Zhang, Xiaofu; Yu, Xiao; Le, Xiaoyun

    2017-10-01

    Improving antifatigue performance of silicon substrate is very important for the development of semiconductor industry. The cracking behavior of silicon under intense pulsed ion beam irradiation was studied by numerical simulation in order to understand the mechanism of induced surface peeling observed by experimental means. Using molecular dynamics simulation based on Stillinger Weber potential, tensile effect on crack growth and propagation in single crystal silicon was investigated. Simulation results reveal that stress-strain curves of single crystal silicon at a constant strain rate can be divided into three stages, which are not similar to metal stress-strain curves; different tensile load velocities induce difference of single silicon crack formation speed; the layered stress results in crack formation in single crystal silicon. It is concluded that the crack growth and propagation is more sensitive to strain rate, tensile load velocity, stress distribution in single crystal silicon.

  19. Single crystal diffractometer for solid state physics at pulsed neutron source

    International Nuclear Information System (INIS)

    Takahashi, Miwako; Abe, Hiroshi; Ishigaki, Toru

    2002-05-01

    KEK Neutron Diffraction Facility held this meeting on September 1, 2002. The objects of meeting were to discuss themes and future of single crystal diffraction of pulsed neutron source, because 3GeV/1MW intense neutron beam will be produced by the high intensity proton accelerator project after 4 year. This report was made to discuss needs of the single crystal diffractometer in the high intensity proton accelerator project for research of solid-state physics. Paper, needs of this apparatus, suggestions to how to put forward proposal and themes are included. 16 papers were read in this meeting. The subjects of these papers consisted of the neutron diffractometer such as FOX, FONDER, EXCED, SXD and it by intense pulsed neutron source, powder, MRP, high Tc superconductors, and binary alloy. (S.Y.)

  20. Performances of BNL high-intensity synchrotrons

    International Nuclear Information System (INIS)

    Weng, W.T.

    1998-03-01

    The AGS proton synchrotron was completed in 1960 with initial intensity in the 10 to the 10th power proton per pulse (ppp) range. Over the years, through many upgrades and improvements, the AGS now reached an intensity record of 6.3 x 10 13 ppp, the highest world intensity record for a proton synchrotron on a single pulse basis. At the same time, the Booster reached 2.2 x 10 13 ppp surpassing the design goal of 1.5 x 10 13 ppp due to the introduction of second harmonic cavity during injection. The intensity limitation caused by space charge tune spread and its relationship to injection energy at 50 MeV, 200 MeV, and 1,500 MeV will be presented as well as many critical accelerator manipulations. BNL currently participates in the design of an accumulator ring for the SNS project at Oak Ridge. The status on the issues of halo formation, beam losses and collimation are also presented

  1. Rise time of voltage pulses in NbN superconducting single photon detectors

    International Nuclear Information System (INIS)

    Smirnov, K. V.; Divochiy, A. V.; Karpova, U. V.; Morozov, P. V.; Vakhtomin, Yu. B.; Seleznev, V. A.; Sidorova, M. V.; Zotova, A. N.; Vodolazov, D. Yu.

    2016-01-01

    We have found experimentally that the rise time of voltage pulse in NbN superconducting single photon detectors increases nonlinearly with increasing the length of the detector L. The effect is connected with dependence of resistance of the detector R n , which appears after photon absorption, on its kinetic inductance L k and, hence, on the length of the detector. This conclusion is confirmed by our calculations in the framework of two temperature model.

  2. Nonlinear pulse propagation in a single- and a few-cycle regimes ...

    Indian Academy of Sciences (India)

    In this work, we study the effect of the delayed nonlinear response (intrapulse. Raman effect) on the propagation characteristics of a single- and a few-cycle pulse at 0.8 µm wavelength in a silica glass ..... 0.03923 fs2/µm, Tr = 3 fs and σ = 0.7. effect leads to a frequency shift toward higher frequencies, in the trailing edge and.

  3. Rise time of voltage pulses in NbN superconducting single photon detectors

    Energy Technology Data Exchange (ETDEWEB)

    Smirnov, K. V. [Moscow State Pedagogical University, 1 Malaya Pirogovskaya St., 119435 Moscow (Russian Federation); CJSC “Superconducting Nanotechnology” (Scontel), 5/22-1 Rossolimo St., 119021 Moscow (Russian Federation); National Research University Higher School of Economics, Moscow Institute of Electronics and Mathematics, 34 Tallinskaya St., 109028 Moscow (Russian Federation); Divochiy, A. V.; Karpova, U. V.; Morozov, P. V. [CJSC “Superconducting Nanotechnology” (Scontel), 5/22-1 Rossolimo St., 119021 Moscow (Russian Federation); Vakhtomin, Yu. B.; Seleznev, V. A. [Moscow State Pedagogical University, 1 Malaya Pirogovskaya St., 119435 Moscow (Russian Federation); CJSC “Superconducting Nanotechnology” (Scontel), 5/22-1 Rossolimo St., 119021 Moscow (Russian Federation); Sidorova, M. V. [Moscow State Pedagogical University, 1 Malaya Pirogovskaya St., 119435 Moscow (Russian Federation); Zotova, A. N.; Vodolazov, D. Yu. [Institute for Physics of Microstructure, Russian Academy of Sciences, GSP-105, 603950 Nizhny Novgorod (Russian Federation); Lobachevsky State University of Nizhny Novgorod, 23 Gagarin Avenue, 603950 Nizhny Novgorod (Russian Federation)

    2016-08-01

    We have found experimentally that the rise time of voltage pulse in NbN superconducting single photon detectors increases nonlinearly with increasing the length of the detector L. The effect is connected with dependence of resistance of the detector R{sub n}, which appears after photon absorption, on its kinetic inductance L{sub k} and, hence, on the length of the detector. This conclusion is confirmed by our calculations in the framework of two temperature model.

  4. Broadband single-pulse CARS spectra in a fired internal combustion engine.

    Science.gov (United States)

    Klick, D; Marko, K A; Rimai, L

    1981-04-01

    The first known broadband single-pulse coherent anti-Stokes Raman scattering (CARS) measurements within the cylinder of a firing internal combustion engine are reported. Postcombustion temperature and carbon monoxide concentration are probed with 1-mm(3) spatial resolution and 10-nsec temporal resolution. Space- and time-resolved measurements, as presented here, are shown to be necessary for the study of fluctuating systems such as engines.

  5. Single-pulse x-ray diffraction using polycapillary optics for in situ dynamic diffraction

    Energy Technology Data Exchange (ETDEWEB)

    Maddox, B. R., E-mail: maddox3@llnl.gov; Akin, M. C., E-mail: akin1@llnl.gov; Teruya, A.; Hunt, D.; Hahn, D.; Cradick, J. [Lawrence Livermore National Laboratory, Livermore, California 94550 (United States); Morgan, D. V. [National Security Technologies LLC, Los Alamos, New Mexico 87544 (United States)

    2016-08-15

    Diagnostic use of single-pulse x-ray diffraction (XRD) at pulsed power facilities can be challenging due to factors such as the high flux and brightness requirements for diffraction and the geometric constraints of experimental platforms. By necessity, the x-ray source is usually positioned very close, within a few inches of the sample. On dynamic compression platforms, this puts the x-ray source in the debris field. We coupled x-ray polycapillary optics to a single-shot needle-and-washer x-ray diode source using a laser-based alignment scheme to obtain high-quality x-ray diffraction using a single 16 ns x-ray pulse with the source >1 m from the sample. The system was tested on a Mo sample in reflection geometry using 17 keV x-rays from a Mo anode. We also identified an anode conditioning effect that increased the x-ray intensity by 180%. Quantitative measurements of the x-ray focal spot produced by the polycapillary yielded a total x-ray flux on the sample of 3.3 ± 0.5 × 10{sup 7} molybdenum Kα photons.

  6. A Single-Chip CMOS Pulse Oximeter with On-Chip Lock-In Detection.

    Science.gov (United States)

    He, Diwei; Morgan, Stephen P; Trachanis, Dimitrios; van Hese, Jan; Drogoudis, Dimitris; Fummi, Franco; Stefanni, Francesco; Guarnieri, Valerio; Hayes-Gill, Barrie R

    2015-07-14

    Pulse oximetry is a noninvasive and continuous method for monitoring the blood oxygen saturation level. This paper presents the design and testing of a single-chip pulse oximeter fabricated in a 0.35 µm CMOS process. The chip includes photodiode, transimpedance amplifier, analogue band-pass filters, analogue-to-digital converters, digital signal processor and LED timing control. The experimentally measured AC and DC characteristics of individual circuits including the DC output voltage of the transimpedance amplifier, transimpedance gain of the transimpedance amplifier, and the central frequency and bandwidth of the analogue band-pass filters, show a good match (within 1%) with the circuit simulations. With modulated light source and integrated lock-in detection the sensor effectively suppresses the interference from ambient light and 1/f noise. In a breath hold and release experiment the single chip sensor demonstrates consistent and comparable performance to commercial pulse oximetry devices with a mean of 1.2% difference. The single-chip sensor enables a compact and robust design solution that offers a route towards wearable devices for health monitoring.

  7. A Single-Chip CMOS Pulse Oximeter with On-Chip Lock-In Detection

    Directory of Open Access Journals (Sweden)

    Diwei He

    2015-07-01

    Full Text Available Pulse oximetry is a noninvasive and continuous method for monitoring the blood oxygen saturation level. This paper presents the design and testing of a single-chip pulse oximeter fabricated in a 0.35 µm CMOS process. The chip includes photodiode, transimpedance amplifier, analogue band-pass filters, analogue-to-digital converters, digital signal processor and LED timing control. The experimentally measured AC and DC characteristics of individual circuits including the DC output voltage of the transimpedance amplifier, transimpedance gain of the transimpedance amplifier, and the central frequency and bandwidth of the analogue band-pass filters, show a good match (within 1% with the circuit simulations. With modulated light source and integrated lock-in detection the sensor effectively suppresses the interference from ambient light and 1/f noise. In a breath hold and release experiment the single chip sensor demonstrates consistent and comparable performance to commercial pulse oximetry devices with a mean of 1.2% difference. The single-chip sensor enables a compact and robust design solution that offers a route towards wearable devices for health monitoring.

  8. Anisotropy effect of crater formation on single crystal silicon surface under intense pulsed ion beam irradiation

    Science.gov (United States)

    Shen, Jie; Yu, Xiao; Zhang, Jie; Zhong, Haowen; Cui, Xiaojun; Liang, Guoying; Yu, Xiang; Huang, Wanying; Shahid, Ijaz; Zhang, Xiaofu; Yan, Sha; Le, Xiaoyun

    2018-04-01

    Due to the induced extremely fast thermal and dynamic process, Intense Pulsed Ion Beam (IPIB) is widely applied in material processing, which can bring enhanced material performance and surface craters as well. To investigate the craters' formation mechanism, a specific model was built with Finite Element Methods (FEM) to simulate the thermal field on irradiated single crystal silicon. The direct evidence for the existence of the simulated 6-fold rotational symmetric thermal distribution was provided by electron microscope images obtained on single crystal silicon. The correlation of the experiment and simulation is of great importance to understand the interaction between IPIB and materials.

  9. Partial Shading Detection in Solar System Using Single Short Pulse of Load

    Directory of Open Access Journals (Sweden)

    Bartczak Mateusz

    2017-03-01

    Full Text Available A single photovoltaic panel under uniform illumination has only one global maximum power point, but the same panel in irregularly illuminated conditions can have more maxima on its power-voltage curve. The irregularly illuminated conditions in most cases are results of partial shading. In the work a single short pulse of load is used to extract information about partial shading. This information can be useful and can help to make some improvements in existing MPPT algorithms. In the paper the intrinsic capacitance of a photovoltaic system is used to retrieve occurrence of partial shading.

  10. Single-shot femtosecond-pulsed phase-shifting digital holography.

    Science.gov (United States)

    Kakue, Takashi; Itoh, Seiya; Xia, Peng; Tahara, Tatsuki; Awatsuji, Yasuhiro; Nishio, Kenzo; Ura, Shogo; Kubota, Toshihiro; Matoba, Osamu

    2012-08-27

    Parallel phase-shifting digital holography is capable of three-dimensional measurement of a dynamically moving object with a single-shot recording. In this letter, we demonstrated a parallel phase-shifting digital holography using a single femtosecond light pulse whose central wavelength and temporal duration were 800 nm and 96 fs, respectively. As an object, we set spark discharge in atmospheric pressure air induced by applying a high voltage to between two electrodes. The instantaneous change in phase caused by the spark discharge was clearly reconstructed. The reconstructed phase image shows the change of refractive index of air was -3.7 × 10(-4).

  11. Single shot three-dimensional pulse sequence for hyperpolarized13C MRI.

    Science.gov (United States)

    Wang, Jiazheng; Wright, Alan J; Hu, De-En; Hesketh, Richard; Brindle, Kevin M

    2017-02-01

    Metabolic imaging with hyperpolarized 13 C-labeled cell substrates is a promising technique for imaging tissue metabolism in vivo. However, the transient nature of the hyperpolarization, and its depletion following excitation, limits the imaging time and the number of excitation pulses that can be used. We describe here a single-shot three-dimensional (3D) imaging sequence and demonstrate its capability to generate 13 C MR images in tumor-bearing mice injected with hyperpolarized [1- 13 C]pyruvate. The pulse sequence acquires a stack-of-spirals at two spin echoes after a single excitation pulse and encodes the kz-dimension in an interleaved manner to enhance robustness to B 0 inhomogeneity. Spectral-spatial pulses are used to acquire dynamic 3D images from selected hyperpolarized 13 C-labeled metabolites. A nominal spatial/temporal resolution of 1.25 × 1.25 × 2.5 mm 3  × 2 s was achieved in tumor images of hyperpolarized [1- 13 C]pyruvate and [1- 13 C]lactate acquired in vivo. Higher resolution in the z-direction, with a different k-space trajectory, was demonstrated in measurements on a thermally polarized [1- 13 C]lactate phantom. The pulse sequence is capable of imaging hyperpolarized 13 C-labeled substrates at relatively high spatial and temporal resolutions and is robust to moderate system imperfections. Magn Reson Med 77:740-752, 2017. © 2016 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 2016 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.

  12. Evolution of energy deposition processes in anthracene single crystal from photochemistry to radiation chemistry under excitation with synchrotron radiation from 3 to 700 eV

    International Nuclear Information System (INIS)

    Nakagawa, Kazumichi; Jin, Zhaohui; Shimoyama, Iwao; Miyake, Yasuyuki; Ueno, Madoka; Kishigami, Yoichi; Horiuchi, Hiroki; Tanaka, Masahito; Kaneko, Fusae; Nishimagi, Hironobu; Kobayashi, Hiroyuki; Kotani, Masahiro

    2008-01-01

    Absolute values of quantum yield Φ(hν) of singlet exciton formation in anthracene single crystals were measured as a function of photon energy hν, with the usage of synchrotron radiation (SR) in 3-700 eV region. Values of Φ(hν) were found to increase linearly for hν≥75 eV. For hν≤40 eV, values of Φ(hν) gave a wealth of structures and are not linear to hν. Because number of secondary electrons produced by radiation is thought to increase in proportional to the incident photon energy, it is natural to conclude that the radiation chemistry effect becomes dominant above 75 eV. On the other hand, values of Φ(hν) showed response due to resonance rather than linear dependence with hν, which implies that the photochemical effect is dominant below 40 eV

  13. A single-probe heat pulse method for estimating sap velocity in trees.

    Science.gov (United States)

    López-Bernal, Álvaro; Testi, Luca; Villalobos, Francisco J

    2017-10-01

    Available sap flow methods are still far from being simple, cheap and reliable enough to be used beyond very specific research purposes. This study presents and tests a new single-probe heat pulse (SPHP) method for monitoring sap velocity in trees using a single-probe sensor, rather than the multi-probe arrangements used up to now. Based on the fundamental conduction-convection principles of heat transport in sapwood, convective velocity (V h ) is estimated from the temperature increase in the heater after the application of a heat pulse (ΔT). The method was validated against measurements performed with the compensation heat pulse (CHP) technique in field trees of six different species. To do so, a dedicated three-probe sensor capable of simultaneously applying both methods was produced and used. Experimental measurements in the six species showed an excellent agreement between SPHP and CHP outputs for moderate to high flow rates, confirming the applicability of the method. In relation to other sap flow methods, SPHP presents several significant advantages: it requires low power inputs, it uses technically simpler and potentially cheaper instrumentation, the physical damage to the tree is minimal and artefacts caused by incorrect probe spacing and alignment are removed. © 2017 The Authors. New Phytologist © 2017 New Phytologist Trust.

  14. Self-phase modulation of a single-cycle terahertz pulse by nonlinear free-carrier response in a semiconductor

    DEFF Research Database (Denmark)

    Turchinovich, Dmitry; Hvam, Jørn Märcher; Hoffmann, Matthias C.

    2012-01-01

    We investigate the self-phase modulation (SPM) of a single-cycle terahertz pulse in a semiconductor, using bulk n-GaAs as a model system. The SPM arises from the heating of free electrons in the electric field of the terahertz pulse, leading to an ultrafast reduction of the plasma frequency...

  15. Single-shot pulse duration and intensity diagnostic for 10-ps MeV gamma pulses based on interferometry

    Science.gov (United States)

    Peng, Bo-dong; Hei, Dong-wei; Song, Yan; Liu, Jun; Zhao, Jun

    2018-04-01

    To measure the temporal width and the intensity evolution versus time of a MeV gamma pulse generated by a Compton Scatter Source, a time-space conversion method is proposed. This design is based on the consideration that the temporal length of the MeV pulse is proportional to the spatial length of the pulse in a certain semiconductor. The spatial length and the intensity evolution versus time of the MeV pulse can be obtained by recording the region of the refractive index change that is induced by the MeV pulse. The simulation suggests that the equivalent temporal spread of a mono-energy MeV δ pulse in a bulk semiconductor is on the order of picoseconds and does not vary significantly with photon energy and material type. According to our analysis, the excess carrier generation time, excess carrier diffusion and recombination do not significantly influence the temporal resolution of this method. The temporal response of the refractive index change to a MeV pulse is also fast enough to meet the measurement requirements. The signal generation process for measuring a 10-ps MeV pulse with a 200-fs probe beam is analyzed, revealing that the transverse size of the MeV pulse does not influence the temporal resolution of this method.

  16. A Sensitive Method for Examining Whole Cell Biochemical Composition in Single Cells of Filamentous Fungi using Synchrotron FTIR Spectromicroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Konstantin,J.; Gough, K.; Julian, R.; Kaminskyj, S.

    2008-01-01

    Cell function is related to cell composition. The asexual state of filamentous fungi (molds and mildews) has two main life cycle stages: vegetative hyphae for substrate colonization and nutrient acquisition, and asexual spores for survival and dispersal. Hyphal composition changes over a few tens of microns during growth and maturation; spores are different from hyphae. Most biochemical analyses are restricted to studying a few components at high spatial resolution (e.g. histochemistry) or many compounds at low spatial resolution (e.g. GC-MS). Synchrotron FTIR spectromicroscopy can be used to study fungal cell biology by fingerprinting varieties of carbohydrates, proteins, and lipids at about 6 microm spatial resolution. FTIR can distinguish fungal species and changes during hyphal growth, and reveals that even fungi grown under optimal vs mildly stressed conditions exhibit dramatic biochemical changes without obvious morphological effects. Here we compare hypha and spore composition of two fungi, Neurospora and Rhizopus. There are clear biochemical changes when Neurospora hyphae commit to spore development, during spore maturation and following germination, many of which are consistent with results from molecular genetics, but have not been shown before at high spatial resolution. Rhizopus spores develop within a fluid-containing sporangium that becomes dry at maturity. Rhizopus spores had similar protein content and significantly more carbohydrate than the sporangial fluid, both of which are novel findings.

  17. Single cell synchrotron FT-IR microspectroscopy reveals a link between neutral lipid and storage carbohydrate fluxes in S. cerevisiae.

    Directory of Open Access Journals (Sweden)

    Frédéric Jamme

    Full Text Available In most organisms, storage lipids are packaged into specialized structures called lipid droplets. These contain a core of neutral lipids surrounded by a monolayer of phospholipids, and various proteins which vary depending on the species. Hydrophobic structural proteins stabilize the interface between the lipid core and aqueous cellular environment (perilipin family of proteins, apolipoproteins, oleosins. We developed a genetic approach using heterologous expression in Saccharomyces cerevisiae of the Arabidopsis thaliana lipid droplet oleosin and caleosin proteins AtOle1 and AtClo1. These transformed yeasts overaccumulate lipid droplets, leading to a specific increase in storage lipids. The phenotype of these cells was explored using synchrotron FT-IR microspectroscopy to investigate the dynamics of lipid storage and cellular carbon fluxes reflected as changes in spectral fingerprints. Multivariate statistical analysis of the data showed a clear effect on storage carbohydrates and more specifically, a decrease in glycogen in our modified strains. These observations were confirmed by biochemical quantification of the storage carbohydrates glycogen and trehalose. Our results demonstrate that neutral lipid and storage carbohydrate fluxes are tightly connected and co-regulated.

  18. Surprise in simplicity: an unusual spectral evolution of a single pulse GRB 151006A

    Science.gov (United States)

    Basak, R.; Iyyani, S.; Chand, V.; Chattopadhyay, T.; Bhattacharya, D.; Rao, A. R.; Vadawale, S. V.

    2017-11-01

    We present a detailed analysis of GRB 151006A, the first gamma-ray burst (GRB) detected by AstroSat Cadmium-Zinc-Telluride Imager (CZTI). We study the long-term spectral evolution by exploiting the capabilities of Fermi and Swift satellites at different phases, which is complemented by the polarization measurement with the CZTI. While the light curve of the GRB in different energy bands shows a simple pulse profile, the spectrum shows an unusual evolution. The first phase exhibits a hard-to-soft evolution until ∼16-20 s, followed by a sudden increase in the spectral peak reaching a few MeV. Such a dramatic change in the spectral evolution in the case of a single pulse burst is reported for the first time. This is captured by all models we used namely, Band function, blackbody+Band and two blackbodies+power law. Interestingly, the Fermi Large Area Telescope also detects its first photon (>100 MeV) during this time. This new injection of energy may be associated with either the beginning of afterglow phase, or a second hard pulse of the prompt emission itself that, however, is not seen in the otherwise smooth pulse profile. By constructing Bayesian blocks and studying the hardness evolution we find a good evidence for a second hard pulse. The Swift data at late epochs (>T90 of the GRB) also show a significant spectral evolution consistent with the early second phase. The CZTI data (100-350 keV), though having low significance (1σ), show high values of polarization in the two epochs (77-94 per cent), in agreement with our interpretation.

  19. A Comparative Study of Single-pulse and Double-pulse Laser-Induced Breakdown Spectroscopy with Uranium-containing Samples.

    Science.gov (United States)

    Skrodzki, Patrick J; Becker, Jason R; Diwakar, Prasoon K; Harilal, Sivanandan S; Hassanein, Ahmed

    2016-03-01

    Laser-induced breakdown spectroscopy (LIBS) holds potential advantages in special nuclear material (SNM) sensing and nuclear forensics, which require rapid analysis, minimal sample preparation, and stand-off distance capability. SNM, such as U, however, result in crowded emission spectra with LIBS, and characteristic emission lines are challenging to discern. It is well-known that double-pulse LIBS (DPLIBS) improves the signal intensity for analytes over conventional single-pulse LIBS (SPLIBS). This study investigates the U signal in a glass matrix using DPLIBS and compares it to signal obtained using SPLIBS. Double-pulse LIBS involves sequential firing of a 1.06 µm Nd:YAG pre-pulse and 10.6 µm TEA CO2 heating pulse in a near collinear geometry. Optimization of experimental parameters including inter-pulse delay and energy follows identification of characteristic lines for the bulk analyte Ca and the minor constituent analyte U for both DPLIBS and SPLIBS. Spatial and temporal coupling of the two pulses in the proposed DPLIBS technique yields improvements in analytical merits with a negligible increase in damage to the sample compared to SPLIBS. Subsequently, the study discusses optimum plasma emission conditions of U lines and relative figures of merit in both SPLIBS and DPLIBS. Investigation into plasma characteristics also addresses plausible mechanisms related to the observed U analyte signal variation between SPLIBS and DPLIBS. © The Author(s) 2016.

  20. Label-free screening of single biomolecules through resistive pulse sensing technology for precision medicine applications

    Science.gov (United States)

    Harrer, S.; Kim, S. C.; Schieber, C.; Kannam, S.; Gunn, N.; Moore, S.; Scott, D.; Bathgate, R.; Skafidas, S.; Wagner, J. M.

    2015-05-01

    Employing integrated nano- and microfluidic circuits for detecting and characterizing biological compounds through resistive pulse sensing technology is a vibrant area of research at the interface of biotechnology and nanotechnology. Resistive pulse sensing platforms can be customized to study virtually any particle of choice which can be threaded through a fluidic channel and enable label-free single-particle interrogation with the primary read-out signal being an electric current fingerprint. The ability to perform label-free molecular screening with single-molecule and even single binding site resolution makes resistive pulse sensing technology a powerful tool for analyzing the smallest units of biological systems and how they interact with each other on a molecular level. This task is at the core of experimental systems biology and in particular ‘omics research which in combination with next-generation DNA-sequencing and next-generation drug discovery and design forms the foundation of a novel disruptive medical paradigm commonly referred to as personalized medicine or precision medicine. DNA-sequencing has approached the 1000-Dollar-Genome milestone allowing for decoding a complete human genome with unmatched speed and at low cost. Increased sequencing efficiency yields massive amounts of genomic data. Analyzing this data in combination with medical and biometric health data eventually enables understanding the pathways from individual genes to physiological functions. Access to this information triggers fundamental questions for doctors and patients alike: what are the chances of an outbreak for a specific disease? Can individual risks be managed and if so how? Which drugs are available and how should they be applied? Could a new drug be tailored to an individual’s genetic predisposition fast and in an affordable way? In order to provide answers and real-life value to patients, the rapid evolvement of novel computing approaches for analyzing big data in

  1. Development of a silicon microstrip detector with single photon sensitivity for fast dynamic diffraction experiments at a synchrotron radiation beam

    Science.gov (United States)

    Arakcheev, A.; Aulchenko, V.; Kudashkin, D.; Shekhtman, L.; Tolochko, B.; Zhulanov, V.

    2017-06-01

    Time-resolved experiments on the diffraction of synchrotron radiation (SR) from crystalline materials provide information on the evolution of a material structure after a heat, electron beam or plasma interaction with a sample under study. Changes in the material structure happen within a microsecond scale and a detector with corresponding parameters is needed. The SR channel 8 of the VEPP-4M storage ring provides radiation from the 7-pole wiggler that allows to reach several tens photons within one μs from a tungsten crystal for the most intensive diffraction peak. In order to perform experiments that allow to measure the evolution of tungsten crystalline structure under the impact of powerful laser beam, a new detector is developed, that can provide information about the distribution of a scattered SR flux in space and its evolution in time at a microsecond scale. The detector is based on the silicon p-in-n microstrip sensor with DC-coupled metal strips. The sensor contains 1024 30 mm long strips with a 50 μm pitch. 64 strips are bonded to the front-end electronics based on APC128 ASICs. The APC128 ASIC contains 128 channels that consist of a low noise integrator with 32 analogue memory cells each. The integrator equivalent noise charge is about 2000 electrons and thus the signal from individual photons with energy above 40 keV can be observed. The signal can be stored at the analogue memory with 10 MHz rate. The first measurements with the beam scattered from a tungsten crystal with energy near 60 keV demonstrated the capability of this prototype to observe the spatial distribution of the photon flux with the intensity from below one photon per channel up to 0~10 photons per channel with a frame rate from 10 kHz up to 1 MHz.

  2. Synchrotron radiation

    International Nuclear Information System (INIS)

    Pattison, P.; Quinn, P.

    1990-01-01

    This report details the activities in synchrotron radiation and related areas at Daresbury Laboratory during 1989/90. The number and scope of the scientific reports submitted by external users and in-house staff is a reflection of the large amount of scheduled beamtime and high operating efficiency achieved at the Synchrotron Radiation Source (SRS) during the past year. Over 4000 hours of user beam were available, equivalent to about 80% of the total scheduled time. Many of the reports collected here illustrate the increasing technical complexity of the experiments now being carried out at Daresbury. Provision of the appropriate technical and scientific infrastructure and support is a continuing challenge. The development of the Materials Science Laboratory together with the existing Biological Support Laboratory will extend the range of experiments which can be carried out on the SRS. This will particularly facilitate work in which the sample must be prepared or characterised immediately before or during an experiment. The year 1989/90 has also seen a substantial upgrade of several stations, especially in the area of x-ray optics. Many of the advantages of the High Brightness Lattice can only be exploited effectively with the use of focusing optics. As the performance of these stations improves, the range of experiments which are feasible on the SRS will be extended significantly. (author)

  3. Single-pulse CARS based multimodal nonlinear optical microscope for bioimaging.

    Science.gov (United States)

    Kumar, Sunil; Kamali, Tschackad; Levitte, Jonathan M; Katz, Ori; Hermann, Boris; Werkmeister, Rene; Považay, Boris; Drexler, Wolfgang; Unterhuber, Angelika; Silberberg, Yaron

    2015-05-18

    Noninvasive label-free imaging of biological systems raises demand not only for high-speed three-dimensional prescreening of morphology over a wide-field of view but also it seeks to extract the microscopic functional and molecular details within. Capitalizing on the unique advantages brought out by different nonlinear optical effects, a multimodal nonlinear optical microscope can be a powerful tool for bioimaging. Bringing together the intensity-dependent contrast mechanisms via second harmonic generation, third harmonic generation and four-wave mixing for structural-sensitive imaging, and single-beam/single-pulse coherent anti-Stokes Raman scattering technique for chemical sensitive imaging in the finger-print region, we have developed a simple and nearly alignment-free multimodal nonlinear optical microscope that is based on a single wide-band Ti:Sapphire femtosecond pulse laser source. Successful imaging tests have been realized on two exemplary biological samples, a canine femur bone and collagen fibrils harvested from a rat tail. Since the ultra-broad band-width femtosecond laser is a suitable source for performing high-resolution optical coherence tomography, a wide-field optical coherence tomography arm can be easily incorporated into the presented multimodal microscope making it a versatile optical imaging tool for noninvasive label-free bioimaging.

  4. Communication: The electronic structure of matter probed with a single femtosecond hard x-ray pulse

    Directory of Open Access Journals (Sweden)

    J. Szlachetko

    2014-03-01

    Full Text Available Physical, biological, and chemical transformations are initiated by changes in the electronic configuration of the species involved. These electronic changes occur on the timescales of attoseconds (10−18 s to femtoseconds (10−15 s and drive all subsequent electronic reorganization as the system moves to a new equilibrium or quasi-equilibrium state. The ability to detect the dynamics of these electronic changes is crucial for understanding the potential energy surfaces upon which chemical and biological reactions take place. Here, we report on the determination of the electronic structure of matter using a single self-seeded femtosecond x-ray pulse from the Linac Coherent Light Source hard x-ray free electron laser. By measuring the high energy resolution off-resonant spectrum (HEROS, we were able to obtain information about the electronic density of states with a single femtosecond x-ray pulse. We show that the unoccupied electronic states of the scattering atom may be determined on a shot-to-shot basis and that the measured spectral shape is independent of the large intensity fluctuations of the incoming x-ray beam. Moreover, we demonstrate the chemical sensitivity and single-shot capability and limitations of HEROS, which enables the technique to track the electronic structural dynamics in matter on femtosecond time scales, making it an ideal probe technique for time-resolved X-ray experiments.

  5. Single cell detection using a glass-based optofluidic device fabricated by femtosecond laser pulses.

    Science.gov (United States)

    Kim, Moosung; Hwang, David J; Jeon, Hojeong; Hiromatsu, Kuniaki; Grigoropoulos, Costas P

    2009-01-21

    We demonstrate the fabrication of integrated three-dimensional microchannel and optical waveguide structures inside fused silica for the interrogation and processing of single cells. The microchannels are fabricated by scanning femtosecond laser pulses (523 nm) and subsequent selective wet etching process. Optical waveguides are additionally integrated with the fabricated microchannels by scanning the laser pulse train inside the glass specimen. Single red blood cells (RBC) in diluted human blood inside of the manufactured microchannel were detected by two optical schemes. The first involved sensing the intensity change of waveguide-delivered He-Ne laser light (632.8 nm) induced by the refractive index difference of a cell flowing in the channel. The other approach was via detection of fluorescence emission from dyed RBC excited by Ar laser light (488 nm) delivered by the optical waveguide. The proposed device was tested to detect 23 fluorescent particles per second by increasing the flow rate up to 0.5 microl min(-1). The optical cell detection experiments support potential implementation of a new generation of glass-based optofluidic biochip devices in various single cell treatment processes including laser based cell processing and sensing.

  6. Universal route to optimal few- to single-cycle pulse generation in hollow-core fiber compressors.

    Science.gov (United States)

    Conejero Jarque, E; San Roman, J; Silva, F; Romero, R; Holgado, W; Gonzalez-Galicia, M A; Alonso, B; Sola, I J; Crespo, H

    2018-02-02

    Gas-filled hollow-core fiber (HCF) pulse post-compressors generating few- to single-cycle pulses are a key enabling tool for attosecond science and ultrafast spectroscopy. Achieving optimum performance in this regime can be extremely challenging due to the ultra-broad bandwidth of the pulses and the need of an adequate temporal diagnostic. These difficulties have hindered the full exploitation of HCF post-compressors, namely the generation of stable and high-quality near-Fourier-transform-limited pulses. Here we show that, independently of conditions such as the type of gas or the laser system used, there is a universal route to obtain the shortest stable output pulse down to the single-cycle regime. Numerical simulations and experimental measurements performed with the dispersion-scan technique reveal that, in quite general conditions, post-compressed pulses exhibit a residual third-order dispersion intrinsic to optimum nonlinear propagation within the fiber, in agreement with measurements independently performed in several laboratories around the world. The understanding of this effect and its adequate correction, e.g. using simple transparent optical media, enables achieving high-quality post-compressed pulses with only minor changes in existing setups. These optimized sources have impact in many fields of science and technology and should enable new and exciting applications in the few- to single-cycle pulse regime.

  7. Optical design and studies of a tiled single grating pulse compressor for enhanced parametric space and compensation of tiling errors

    Science.gov (United States)

    Daiya, D.; Patidar, R. K.; Sharma, J.; Joshi, A. S.; Naik, P. A.; Gupta, P. D.

    2017-04-01

    A new optical design of tiled single grating pulse compressor has been proposed, set-up and studied. The parametric space, i.e. the laser beam diameters that can be accommodated in the pulse compressor for the given range of compression lengths, has been calculated and shown to have up to two fold enhancement in comparison to our earlier proposed optical designs. The new optical design of the tiled single grating pulse compressor has an additional advantage of self compensation of various tiling errors like longitudinal and lateral piston, tip and groove density mismatch, compared to the earlier designs. Experiments have been carried out for temporal compression of 650 ps positively chirped laser pulses, at central wavelength 1054 nm, down to 235 fs in the tiled grating pulse compressor set up with the proposed design. Further, far field studies have been performed to show the desired compensation of the tiling errors takes place in the new compressor.

  8. Proposal for a rotating analyser single crystal spectrometer at a pulsed neutron source

    International Nuclear Information System (INIS)

    Geick, R.; Tietze, H.

    1986-01-01

    We propose a new type of crystal analyser time-of-flight spectrometer for elastic and inelastic single crystal measurements at a pulsed neutron source. Using a nonuniformly rotating analyser, a flexibility of the spectrometer is achieved intermediate between that of the crystal analyser time-of-flight spectrometers like MAX and Constant-Q and the triple axis spectrometer. In detail, we discuss constant-(h/2π)ω and constant-(Q/vertical strokeQvertical stroke) scans for our spectrometer and the nonuniform rotation of the analyser necessary for these special scans. (orig.)

  9. Fracture analysis of surface exfoliation on single crystal silicon irradiated by intense pulsed ion beam

    Science.gov (United States)

    Shen, Jie; Shahid, Ijaz; Yu, Xiao; Zhang, Jie; Zhong, Haowen; Cui, Xiaojun; Liang, Guoying; Yu, Xiang; Huang, Wanying; Yan, Sha; Zhang, Gaolong; Zhang, Xiaofu; Le, Xiaoyun

    2017-12-01

    Surface exfoliation was observed on single crystal silicon surface irradiated by Intense Pulsed Ion Beam (IPIB). As the strong transient thermal stress impact induced by IPIB was mainly attributed to the exfoliation, a micro scale model combined with thermal conduction and linear elastic fracture mechanics was built to analyze the thermal stress distribution along the energy deposition process. After computation with finite element method, J integral parameter was applied as the criterion for crack development. It was demonstrated that the exfoliation initiation calls for specific material, crack depth and IPIB parameter. The results are potentially valuable for beam/target selection and IPIB parameter optimization.

  10. High-aspect-ratio grooves fabricated in silicon by a single pass of femtosecond laser pulses

    International Nuclear Information System (INIS)

    Ma Yuncan; Shi Haitao; Si Jinhai; Ren Hai; Chen Tao; Chen Feng; Hou Xun

    2012-01-01

    High-aspect-ratio grooves have been fabricated in silicon by a single pass of femtosecond laser pulses in water and ambient air. Scanning electron microscopy and energy dispersive x-ray spectroscopy were employed to image for the morphology of the photoinduced grooves and analyze the chemical composition in the surrounding of the grooves. It was observed that the sidewall of the grooves fabricated in water was much smoother than that in ambient air, and there were homogeneous nano-scale protrusions on the sidewall of the grooves fabricated in water. Meanwhile, oxygen species, which was incorporated into the grooves fabricated in air, was not observed in those in water.

  11. Single-frequency pulsed Brillouin-thulium fiber laser at 2 µm with nonlinear polarization rotation and active phase modulation

    Science.gov (United States)

    Wang, Xiong; Lv, Haibin; Zhou, Pu; Wu, Weijun; Wang, Xiaolin; Xiao, Hu; Liu, Zejin

    2014-10-01

    We present a single-frequency (SF) pulsed fiber laser at 2 µm based on stimulated Brillouin scattering in a thulium-doped fiber laser. The effective feedback of the fiber laser is quite weak to induce pulse operation. Nonlinear polarization rotation and active phase modulation are employed to compress the pulse width and stabilize the pulse train. This SF pulsed Brillouin-thulium fiber laser (BTFL) can generate a stable pulse train with a repetition rate of ˜310 kHz and a pulse width of ˜200 ns. The repetition rate of the pulse train can be adjusted by controlling the cavity length, and the pulse width can be tuned between 200 and 500 ns. The central wavelength locates at 1971.58 nm with an optical signal-to-noise ratio of more than 40 dB, and the linewidth is about 6 MHz. This is the first demonstration of the SF pulsed BTFL as far as we know.

  12. High Power, Repetitive, Stacked Blumlein Pulse Generators Commuted by a Single Switching Element

    Science.gov (United States)

    Bhawalkar, Jayant Dilip

    In this work, the stacked Blumlein pulsers developed at the University of Texas at Dallas were characterized and shown to be versatile sources of pulse power for a variety of applications. These devices consisted of several triaxial Blumleins stacked in series at one end. The lines were charged in parallel and synchronously commuted repetitively with a single switching element at the other end. In this way, relatively low charging voltages were multiplied to give a high discharge voltage across an arbitrary load without the need for complex Marx bank circuitry. Several pulser parameters such as the number of stacked Blumlein lines, line configuration, type of switching element, and the length of the lines, were varied and the waveform characteristics were observed and analyzed. It was shown that these devices are capable of generating fast rising waveforms with a wide range of peak voltage and current values. The generation of high power waveforms with pulse durations in the range of 80-600 ns was demonstrated without degradation of the voltage gains. The results of this work indicated that unlike generators based on stacked transmission lines, the effects of parasitic modes were not appreciable for the stacked Blumlein pulsers. Opportunities for tactically packaging these pulsers were also investigated and a significant reduction in their size and weight was demonstrated. For this, dielectric lifetime and Blumlein spacing studies were performed on small scale prototypes. In addition to production of intense X-ray pulses, the possible applications for these novel pulsers include driving magnetrons for high power microwave generation, pumping laser media, or powering e-beam diodes. They could also serve as compact, tabletop sources of high power pulses for various research experiments.

  13. Infrared synchrotron radiation from electron storage rings

    International Nuclear Information System (INIS)

    Duncan, W.D.; Williams, G.P.

    1983-01-01

    Simple and useful approximations, valid at infrared wavelengths, to the equations for synchrotron radiation are presented and used to quantify the brightness and power advantage of current synchrotron radiation light sources over conventional infrared broadband laboratory sources. The Daresbury Synchrotron Radiation Source (SRS) and the Brookhaven National Synchrotron Light Source (vacuum ultraviolet) [NSLS(VUV)] storage rings are used as examples in the calculation of the properties of infrared synchrotron radiation. The pulsed nature of the emission is also discussed, and potential areas of application for the brightness, power, and time structure advantages are presented. The use of infrared free electron lasers and undulators on the next generation of storage ring light sources is briefly considered

  14. In-situ determination of metallic variation and multi-association in single particles by combining synchrotron microprobe, sequential chemical extraction and multivariate statistical analysis.

    Science.gov (United States)

    Zhu, Yu-Min; Zhang, Hua; Fan, Shi-Suo; Wang, Si-Jia; Xia, Yi; Shao, Li-Ming; He, Pin-Jing

    2014-07-15

    Due to the heterogeneity of metal distribution, it is challenging to identify the speciation, source and fate of metals in solid samples at micro scales. To overcome these challenges single particles of air pollution control residues were detected in situ by synchrotron microprobe after each step of chemical extraction and analyzed by multivariate statistical analysis. Results showed that Pb, Cu and Zn co-existed as acid soluble fractions during chemical extraction, regardless of their individual distribution as chlorides or oxides in the raw particles. Besides the forms of Fe2O3, MnO2 and FeCr2O4, Fe, Mn, Cr and Ni were closely associated with each other, mainly as reducible fractions. In addition, the two groups of metals had interrelations with the Si-containing insoluble matrix. The binding could not be directly detected by micro-X-ray diffraction (μ-XRD) and XRD, suggesting their partial existence as amorphous forms or in the solid solution. The combined method on single particles can effectively determine metallic multi-associations and various extraction behaviors that could not be identified by XRD, μ-XRD or X-ray absorption spectroscopy. The results are useful for further source identification and migration tracing of heavy metals. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. Two-dimensional micro-beam imaging of trace elements in a single plankton measured by a synchrotron radiation X-ray fluorescence analysis

    International Nuclear Information System (INIS)

    Ezoe, Masako; Sasaki, Miho; Hokura, Akiko; Nakai, Izumi; Terada, Yasuko; Yoshinaga, Tatsuki; Tukamoto, Katsumi; Hagiwara, Atsushi

    2002-01-01

    Two-dimensional imaging and a quantitative analysis of trace elements in rotifer, Brachionus plicatilis, belonging to zooplankton, were carried out by a synchrotron radiation X-ray fluorescence analysis (SR-XRF). The XRF imaging revealed that female rotifers accumulated Fe and Zn in the digestive organ and Fe, Zn, Cu, and Ca in the sexual organs, while the Mn level was high in the head. From a quantitative analysis by inductively coupled plasma mass spectrometry (ICP-MS), we found that rotifers eat the chlorella and accumulate the above elements in the body. The result of quantitative analyses of Mn, Cu, and Zn by SR-XRF in a single sample is in fair agreement with the average values determined by ICP-MS analyses, which were obtained by measuring a large number of rotifers, digested by nitric acid. The present study has demonstrated that SR-XRF is an effective tool for the trace element analysis of a single individual of rotifer. (author)

  16. Single-shot spectro-temporal characterization of XUV pulses from a seeded free-electron laser

    Science.gov (United States)

    de Ninno, Giovanni; Gauthier, David; Mahieu, Benoît; Ribič, Primož Rebernik; Allaria, Enrico; Cinquegrana, Paolo; Danailov, Miltcho Bojanov; Demidovich, Alexander; Ferrari, Eugenio; Giannessi, Luca; Penco, Giuseppe; Sigalotti, Paolo; Stupar, Matija

    2015-08-01

    Intense ultrashort X-ray pulses produced by modern free-electron lasers (FELs) allow one to probe biological systems, inorganic materials and molecular reaction dynamics with nanoscale spatial and femtoscale temporal resolution. These experiments require the knowledge, and possibly the control, of the spectro-temporal content of individual pulses. FELs relying on seeding have the potential to produce spatially and temporally fully coherent pulses. Here we propose and implement an interferometric method, which allows us to carry out the first complete single-shot spectro-temporal characterization of the pulses, generated by an FEL in the extreme ultraviolet spectral range. Moreover, we provide the first direct evidence of the temporal coherence of a seeded FEL working in the extreme ultraviolet spectral range and show the way to control the light generation process to produce Fourier-limited pulses. Experiments are carried out at the FERMI FEL in Trieste.

  17. Synchrotron topographic evaluation of strain around craters generated by irradiation with X-ray pulses from free electron laser with different intensities

    Czech Academy of Sciences Publication Activity Database

    Wierzchowski, W.; Wieteska, K.; Sobierajski, R.; Klinger, D.; Pelka, J.; Zymierska, D.; Paulmann, C.; Hau-Riege, S.P.; London, R.A.; Graf, A.; Burian, Tomáš; Chalupský, Jaromír; Gaudin, J.; Krzywinski, J.; Moeller, S.; Messerschmidt, M.; Bozek, J.; Bostedt, C.

    2015-01-01

    Roč. 364, Dec (2015), s. 20-26 ISSN 0168-583X Institutional support: RVO:68378271 Keywords : x-ray free electron laser * soft x-ray lasers * irradiation with femtosecond pulses * silicon Subject RIV: BL - Plasma and Gas Discharge Physics OBOR OECD: Fluids and plasma physics (including surface physics) Impact factor: 1.389, year: 2015

  18. Synchrotron-radiation research

    International Nuclear Information System (INIS)

    Cunningham, J.E.

    1982-01-01

    The use of radiation from synchrotron sources has started a renaissance in materials, physics, chemistry, and biology. Synchrotron radiation has advantages over conventional x rays in that its source brightness is a thousand times greater throughout a continuous energy spectrum, and resonances are produced with specific electron energy levels. Two major synchrotron radiation sources are operated by DOE: the Stanford Synchrotron Radiation Laboratory at SLAC, and the National Synchrotron Light Source at Brookhaven

  19. Molecular toxicity of triclosan and carbamazepine to green algae Chlorococcum sp.: A single cell view using synchrotron-based Fourier transform infrared spectromicroscopy.

    Science.gov (United States)

    Xin, Xiaying; Huang, Guohe; Liu, Xia; An, Chunjiang; Yao, Yao; Weger, Harold; Zhang, Peng; Chen, Xiujuan

    2017-07-01

    Although pharmaceuticals and personal care products have been used and introduced into the environment in large quantities, little information on potential ecological risks is currently available considering their effects on living organisms. We verified the feasibility of using synchrotron-based Fourier Transform Infrared (SR-FTIR) spectromicroscopy to explore in vivo toxic effects on single living Chlorococcum sp. cells. The study provided important information to achieve a better understanding of the toxic mechanism of triclosan and carbamazepine on living algae Chlorococcum sp.. Triclosan and carbamazepine had distinctive toxic effects on unicellular living algae. Most strikingly, triclosan had more dramatic toxic effects on biochemical components than carbamazepine. Triclosan can affect algae primarily by inhibiting fatty acid synthesis and causing protein aggregation. The toxicity response was irreversible at higher concentration (100.000 μM), but attenuated at lower concentration (0.391 μM) as time extended. Carbamazepine can produce hydrophobic interactions to affect the phospholipid bilayer and work on specific proteins to disfunction the cell membrane. Carbamazepine-exposed cells developed a resistance while extending exposure time. This is the first demonstration from an ecological standpoint that SR-FTIR can provide an innovative approach to reveal the toxicity of emerging pollutants in aquatic environments. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Beam-based compensation of extracted-beam displacement caused by field ringing of pulsed kicker magnets in the 3 GeV rapid cycling synchrotron of the Japan Proton Accelerator Research Complex

    Science.gov (United States)

    Harada, Hiroyuki; Saha, Pranab Kumar; Tamura, Fumihiko; Meigo, Shin-ichiro; Hotchi, Hideaki; Hayashi, Naoki; Kinsho, Michikazu; Hasegawa, Kazuo

    2017-09-01

    Commissioned in October 2007, the 3 GeV rapid cycling synchrotron (RCS) of the Japan Proton Accelerator Research Complex was designed for a high-intensity output beam power of 1 MW. The RCS extracts 3 GeV proton beams of two bunches by using eight pulsed kicker magnets and three DC septum magnets with 25 Hz repetition. These beams are delivered to a materials and life science experimental facility (MLF) and a 50 GeV main ring synchrotron (MR). However, the flat-top fields of the kicker magnets experience ringing that displaces the position of the extracted beam. This displacement is a major issue from the viewpoint of target integrity at the MLF and emittance growth at MR injection. To understand the flat-top uniformity of the total field of all the kickers, the uniformity was measured as the displacement of the extracted beams by using a shorter bunched beam and scanning the entire trigger timing of the kickers. The beam displacement of the first bunch exceeded the required range. Therefore, we performed beam-based measurements kicker by kicker to understand each field-ringing effect, and then we understood the characteristics (strength and temporal structure) of each ringing field. We managed to cancel out the ringing by using all the beam-based measurement data and optimizing each trigger timing. As a result, the field-ringing effect of the kickers was successfully compensated by optimizing the trigger timing of each kicker without hardware upgrades or improvements to the kicker system. By developing an automatic monitoring and correction system, we now have a higher stability of extracted beams during routine user operation. In this paper, we report our procedure for ringing compensation and present supporting experimental results.

  1. Single- and dual-wavelength laser pulses induced modification in 10×(Al/Ti)/Si multilayer system

    Energy Technology Data Exchange (ETDEWEB)

    Salatić, B. [University of Belgrade, Institute of Physics Belgrade, Pregrevica 118, 11080 Belgrade (Serbia); Petrović, S., E-mail: spetro@vinca.rs [University of Belgrade, Institute of Nuclear Science-Vinča, POB 522, 11001 Belgrade (Serbia); Peruško, D. [University of Belgrade, Institute of Nuclear Science-Vinča, POB 522, 11001 Belgrade (Serbia); Čekada, M.; Panjan, P. [Jožef Stefan Institute, Jamova 39, 1000 Ljubljana (Slovenia); Pantelić, D.; Jelenković, B. [University of Belgrade, Institute of Physics Belgrade, Pregrevica 118, 11080 Belgrade (Serbia)

    2016-01-01

    Graphical abstract: - Highlights: • Experimental and numerical study of laser-induced ablation and micro-sized crater formation. • Dual-wavelength pulses induce creation of wider and deeper craters due to synergies of two processes. • Sunflower-like structure formed by dual-wavelength pulses at low irradiance. • Numerical model of nanosecond pulsed laser ablation for complex (Al/Ti)/Si system has been developed. - Abstract: The surface morphology of the ablation craters created in the multilayer 10×(Al/Ti)/Si system by nanosecond laser pulses at single- and dual wavelength has been studied experimentally and numerically. A complex multilayer thin film including ten (Al/Ti) bilayers deposited by ion sputtering on Si(1 0 0) substrate to a total thickness of 260 nm were illuminated at different laser irradiance in the range 0.25–3.5 × 10{sup 9} W cm{sup −2}. Single pulse laser irradiation was done at normal incidence in air, with the single wavelength, either at 532 nm or 1064 nm or with both laser light simultaneously in the ratio of 1:10 for energy per pulse between second harmonic and 1064 nm. Most of the absorbed laser energy was rapidly transformed into heat, producing intensive modifications of composition and morphology on the sample surface. The results show an increase in surface roughness, formation of specific nanostructures, appearance of hydrodynamic features and ablation of surface material with crater formation. Applying a small fraction (10%) of the second harmonic in dual-wavelength pulses, a modification of the 10×(Al/Ti)/Si system by a single laser pulse was reflected in the formation of wider and/or deeper craters. Numerical calculations show that the main physical mechanism in ablation process is normal evaporation without phase explosion. The calculated and experimental results agree relatively well for the whole irradiance range, what makes the model applicable to complex Al/Ti multilayer systems.

  2. A Novel Single Pulsed Electromagnetic Field Stimulates Osteogenesis of Bone Marrow Mesenchymal Stem Cells and Bone Repair

    OpenAIRE

    Fu, Yin-Chih; Lin, Chih-Chun; Chang, Je-Ken; Chen, Chung-Hwan; Tai, I-Chun; Wang, Gwo-Jaw; Ho, Mei-Ling

    2014-01-01

    Pulsed electromagnetic field (PEMF) has been successfully applied to accelerate fracture repair since 1979. Recent studies suggest that PEMF might be used as a nonoperative treatment for the early stages of osteonecrosis. However, PEMF treatment requires a minimum of ten hours per day for the duration of the treatment. In this study, we modified the protocol of the single-pulsed electromagnetic field (SPEMF) that only requires a 3-minute daily treatment. In the in vitro study, cell proliferat...

  3. Synchrotron radiation

    International Nuclear Information System (INIS)

    Seddon, E.A.; Reid, R.J.

    1992-01-01

    Work at the Daresbury SRS has of necessity been interrupted this year (1991/92) due to the incorporation of Wiggler II. However, considerable beamtime was awarded before the shutdown and the major part of this appendix is concerned with the progress reports of the research undertaken then. The reports have been organised under the following broad headings: Molecular Science (19 papers), Surface and Materials Science (169 papers), Biological Science (85 papers), Instrumental and Technique Developments (13 papers) and Accelerator Physics (3 papers). It is hoped that in time the number of contributions on accelerator physics will grow to reflect the in-house activity on, for example, accelerator improvement and design. The research reports are preceded by the Annual Report of the Synchrotron Radiation Facilities Committee, which outlines the research highlights identified by that Committee (also included are details of the current membership of the SRFC and the chairmen of the Beamtime Allocation Panels). Following the reports are the specifications for the beamlines and stations. This year Section 3 contains 289 reports (nearly 100 more than last year) and the number of publications, generated by scientists and engineers who have used or are associated with Daresbury Laboratory facilities, has topped 500 for the first time. (author)

  4. Diode-pumped, single frequency Nd:YLF laser for 60-beam OMEGA laser pulse-shaping system

    International Nuclear Information System (INIS)

    Okishev, A.V.; Seka, W.

    1997-01-01

    The operational conditions of the OMEGA pulse-shaping system require an extremely reliable and low-maintenance master oscillator. The authors have developed a diode-pumped, single-frequency, pulsed Nd:YLF laser for this application. The laser generates Q-switched pulses of ∼160-ns duration and ∼10-microJ energy content at the 1,053-nm wavelength with low amplitude fluctuations (<0.6% rms) and low temporal jitter (<7 ns rms). Amplitude and frequency feedback stabilization systems have been used for high long-term amplitude and frequency stability

  5. Synchrotron Topographic and Diffractometer Studies of Buried Layered Structures Obtained by Implantation with Swift Heavy Ions in Silicon Single Crystals

    International Nuclear Information System (INIS)

    Wierzchowski, W.; Wieteska, K.; Zymierska, D.; Graeff, W.; Czosnyka, T.; Choinski, J.

    2006-01-01

    A distribution of crystallographic defects and deformation in silicon crystals subjected to deep implantation (20-50 μm) with ions of the energy of a few MeV/amu is studied. Three different buried layered structures (single layer, binary buried structure and triple buried structure) were obtained by implantation of silicon single crystals with 184 MeV argon ions, 29.7 MeV boron ions, and 140 MeV argon ions, each implantation at a fluency of 1x10 14 ions cm -2 . The implanted samples were examined by means of white beam X-ray section and projection topography, monochromatic beam topography and by recording local rocking curves with the beam restricted to 50 x 50 μm 2 . The experiment pointed to a very low level of implantation-induced strain (below 10 -5 ). The white beam Bragg case section experiment revealed a layer producing district black contrast located at a depth of the expected mean ion range. The presence of these buried layered structures in studied silicon crystals strongly affected the fringe pattern caused by curvature of the samples. In case of white beam projection and monochromatic beam topographs the implanted areas were revealed as darker regions with a very tiny grain like structure. One may interpret these results as the effect of considerable heating causing annihilation of point defects and formation of dislocation loops connected with point defect clusters. (author)

  6. Ultra-high-precision time control system over any long time delay for laser pump and synchrotron x-ray probe experiment.

    Science.gov (United States)

    Fukuyama, Yoshimitsu; Yasuda, Nobuhiro; Kim, Jungeun; Murayama, Haruno; Ohshima, Takashi; Tanaka, Yoshihito; Kimura, Shigeru; Kamioka, Hayato; Moritomo, Yutaka; Toriumi, Koshiro; Tanaka, Hitoshi; Kato, Kenichi; Ishikawa, Tetsuya; Takata, Masaki

    2008-04-01

    An ultra-high-precision clock system for long time delay has been developed for picosecond time-resolved x-ray diffraction measurements using synchrotron radiation (SR) pulses and synchronized femtosecond laser pulses. The time delay control between pump laser pulse and the probe SR pulse was achieved by combining an in-phase quadrature modulator and a synchronous counter. This method allowed us to change the delay time by a nearly infinite amount while maintaining the precision of +/-8.40 ps. Time-resolved diffraction measurements using the delay control system were demonstrated for precise measurement of an acoustic velocity in a single crystal of gallium arsenide.

  7. Interaction of single-pulse laser energy with bow shock in hypersonic flow

    Directory of Open Access Journals (Sweden)

    Hong Yanji

    2014-04-01

    Full Text Available Pressure sensing and schlieren imaging with high resolution and sensitivity are applied to the study of the interaction of single-pulse laser energy with bow shock at Mach 5. An Nd:YAG laser operated at 1.06 μm, 100 mJ pulse energy is used to break down the hypersonic flow in a shock tunnel. Three-dimensional Navier–Stokes equations are solved with an upwind scheme to simulate the interaction. The pressure at the stagnation point on the blunt body is measured and calculated to examine the pressure variation during the interaction. Schlieren imaging is used in conjunction with the calculated density gradients to examine the process of the interaction. The results show that the experimental pressure at the stagnation point on the blunt body and schlieren imaging fit well with the simulation. The pressure at the stagnation point on the blunt body will increase when the transmission shock approaches the blunt body and decrease with the formation of the rarefied wave. Bow shock is deformed during the interaction. Quasi-stationary waves are formed by high rate laser energy deposition to control the bow shock. The pressure and temperature at the stagnation point on the blunt body and the wave drag are reduced to 50%, 75% and 81% respectively according to the simulation. Schlieren imaging has provided important information for the investigation of the mechanism of the interaction.

  8. Single Pulse Electrical Stimulation to identify epileptogenic cortex: Clinical information obtained from early evoked responses.

    Science.gov (United States)

    Mouthaan, B E; van 't Klooster, M A; Keizer, D; Hebbink, G J; Leijten, F S S; Ferrier, C H; van Putten, M J A M; Zijlmans, M; Huiskamp, G J M

    2016-02-01

    Single Pulse Electrical Stimulation (SPES) probes epileptogenic cortex during electrocorticography. Two SPES responses are described: pathological delayed responses (DR, >100 ms) associated with the seizure onset zone (SOZ) and physiological early responses (ER, 80 Hz, in the SOZ and seizure propagation areas. We used data from 12 refractory epilepsy patients. SPES consisted of 10 pulses of 1 ms, 4-8 mA and 5s interval on adjacent electrodes pairs. Data were available at 2048 samples/s for six and 512 samples/s (22 bits) for eight patients and analyzed in the time-frequency (TF) and time-domain (TD). Electrodes with ERs were stronger associated with SOZ than non-SOZ electrodes. ERs with frequency content >80 Hz exist and are specific for SOZ channels. ERs evoked by stimulation of seizure onset electrodes were associated with electrodes involved in seizure propagation. Analysis of ERs can reveal aspects of pathology, manifested by association with seizure propagation and areas with high ER numbers that coincide with the SOZ. Not only DRs, but also ERs could have clinical value for mapping epileptogenic cortex and help to unravel aspects of the epileptic network. Copyright © 2015 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  9. Modified Dual Three-Pulse Modulation technique for single-phase inverter topology

    Science.gov (United States)

    Sree Harsha, N. R.; Anitha, G. S.; Sreedevi, A.

    2016-01-01

    In a recent paper, a new modulation technique called Dual Three Pulse Modulation (DTPM) was proposed to improve the efficiency of the power converters of the Electric/Hybrid/Fuel-cell vehicles. It was simulated in PSIM 9.0.4 and uses analog multiplexers to generate the modulating signals for the DC/DC converter and inverter. The circuit used is complex and many other simulation softwares do not support the analog multiplexers as well. Also, the DTPM technique produces modulating signals for the converter, which are essentially needed to produce the modulating signals for the inverter. Hence, it cannot be used efficiently to switch the valves of a stand-alone inverter. We propose a new method to generate the modulating signals to switch MOSFETs of a single phase Dual-Three pulse Modulation based stand-alone inverter. The circuits proposed are simulated in Multisim 12.0. We also show an alternate way to switch a DC/DC converter in a way depicted by DTPM technique both in simulation (MATLAB/Simulink) and hardware. The circuitry is relatively simple and can be used for the further investigations of DTPM technique.

  10. ZnO thin films on single carbon fibres fabricated by Pulsed Laser Deposition (PLD)

    Energy Technology Data Exchange (ETDEWEB)

    Krämer, André; Engel, Sebastian [Otto Schott Institute of Materials Research (OSIM), Friedrich Schiller University Jena, Löbdergraben 32, 07743 Jena (Germany); Sangiorgi, Nicola [Institute of Science and Technology for Ceramics – National Research Council of Italy (CNR-ISTEC), via Granarolo 64, 48018 Faenza, RA (Italy); Department of Chemical Science and Technologies, University of Rome Tor Vergata, via della Ricerca Scientifica, 00133 Rome (Italy); Sanson, Alessandra [Institute of Science and Technology for Ceramics – National Research Council of Italy (CNR-ISTEC), via Granarolo 64, 48018 Faenza, RA (Italy); Bartolomé, Jose F. [Instituto de Ciencia de Materiales de Madrid (ICMM), Consejo Superior de Investigaciones Científicas (CSIC), C/Sor Juana Inés de la Cruz 3, 28049 Madrid (Spain); Gräf, Stephan, E-mail: stephan.graef@uni-jena.de [Otto Schott Institute of Materials Research (OSIM), Friedrich Schiller University Jena, Löbdergraben 32, 07743 Jena (Germany); Müller, Frank A. [Otto Schott Institute of Materials Research (OSIM), Friedrich Schiller University Jena, Löbdergraben 32, 07743 Jena (Germany); Center for Energy and Environmental Chemistry Jena (CEEC Jena), Friedrich Schiller University Jena, Philosophenweg 7a, 07743 Jena (Germany)

    2017-03-31

    Highlights: • Carbon fibres were entirely coated with thin films consisting of aligned ZnO crystals. • A Q-switched CO2 laser was utilised as radiation source. • Suitability of ZnO thin films on carbon fibres as photo anodes for DSSC was studied. - Abstract: Single carbon fibres were 360° coated with zinc oxide (ZnO) thin films by pulsed laser deposition using a Q-switched CO{sub 2} laser with a pulse duration τ ≈ 300 ns, a wavelength λ = 10.59 μm, a repetition frequency f{sub rep} = 800 Hz and a peak power P{sub peak} = 15 kW in combination with a 3-step-deposition technique. In a first set of experiments, the deposition process was optimised by investigating the crystallinity of ZnO films on silicon and polished stainless steel substrates. Here, the influence of the substrate temperature and of the oxygen partial pressure of the background gas were characterised by scanning electron microscopy and X-ray diffraction analyses. ZnO coated carbon fibres and conductive glass sheets were used to prepare photo anodes for dye-sensitised solar cells in order to investigate their suitability for energy conversion devices. To obtain a deeper insight of the electronic behaviour at the interface between ZnO and substrate I–V measurements were performed.

  11. Fibre-Bragg-grating writing in single-mode optical fibres by UV femtosecond pulses

    International Nuclear Information System (INIS)

    Zagorul'ko, K A; Kryukov, P G; Dianov, Evgenii M; Dragomir, A; Nikogosyan, D N

    2003-01-01

    Fibre-Bragg-grating writing in single-mode optical fibres by the phase-mask method using 220-fs, 264-nm UV pulses of intensity 31 - 77 GW cm -2 is reported for the first time. The achieved degree of modulation of the photoinduced refractive index was 1.9 x 10 -3 in an H 2 -loaded SMF-28 telecommunication fibre and 1.1 x 10 -3 in a H 2 -free Nufern GF1 fibre. The dependence of the induced refractive index on the intensity for the same irradiation fluences in the case of the H 2 -loaded SMF-28 fibre shows that the refractive index is induced due to nonlinear absorption. (letters)

  12. High efficiency 40 K single-stage Stirling-type pulse tube cryocooler

    Science.gov (United States)

    Wu, X. L.; Chen, L. B.; Pan, C. Z.; Cui, C.; Wang, J. J.; Zhou, Y.

    2017-12-01

    A high efficiency single-stage Stirling-type coaxial pulse tube cryocooler (SPTC) operating at around 40 K has been designed, built and tested. The double-inlet and the inertance tubes together with the gas reservoir were adopted as the phase shifters. Under the conditions of 2.5 MPa charging pressure and 30 Hz operating frequency, the prototype has achieved a no-load temperature of 23.8 K with 330 W of electric input power at a rejection temperature of 279 K. When the input power increases to 400 W, it can achieve a cooling capacity of 4.7 W/40 K while rejecting heat at 279 K yielding an efficiency of 7.02% relative to Carnot. It achieves a cooling capacity of 5 W/40 K with an input power of 450 W. It takes 10 minutes for the SPTC to cool to its no-load temperature of 40 K from 295 K.

  13. Digital quantification of rolling circle amplified single DNA molecules in a resistive pulse sensing nanopore.

    Science.gov (United States)

    Kühnemund, M; Nilsson, M

    2015-05-15

    Novel portable, sensitive and selective DNA sensor methods for bio-sensing applications are required that can rival conventionally used non-portable and expensive fluorescence-based sensors. In this paper, rolling circle amplification (RCA) products are detected in solution and on magnetic particles using a resistive pulse sensing (RPS) nanopore. Low amounts of DNA molecules are detected by padlock probes which are circularized in a strictly target dependent ligation reaction. The DNA-padlock probe-complex is captured on magnetic particles by sequence specific capture oligonucleotides and amplified by a short RCA. Subsequent RPS analysis is used to identify individual particles with single attached RCA products from blank particles. This proof of concept opens up for a novel non-fluorescent digital DNA quantification method that can have many applications in bio-sensing and diagnostic approaches. Copyright © 2014 Elsevier B.V. All rights reserved.

  14. Single shot diffraction of picosecond 8.7-keV x-ray pulses

    Directory of Open Access Journals (Sweden)

    F. H. O’Shea

    2012-02-01

    Full Text Available We demonstrate multiphoton, single shot diffraction images of x rays produced by inverse Compton scattering a high-power CO_{2} laser from a relativistic electron beam, creating a pulse of 8.7 keV x rays. The tightly focused, relatively high peak brightness electron beam and high photon density from the 2 J CO_{2} laser yielded 6×10^{7} x-ray photons over the full opening angle in a single shot. Single shot x-ray diffraction is performed by passing the x rays though a vertical slit and on to a flat silicon (111 crystal. 10^{2} diffracted photons were detected. The spectrum of the detected x rays is compared to simulation. The diffraction and detection of 10^{2} x rays is a key step to a more efficient time resolved diagnostic in which the number of observed x rays might reach 10^{4}; enabling a unique, flexible x-ray source as a sub-ps resolution diagnostic for studying the evolution of chemical reactions, lattice deformation and melting, and magnetism.

  15. Serum albumin binding sites properties in donors and in schizophrenia patients: the study of fluorescence decay of the probe K-35 using S-60 synchrotron pulse excitation

    International Nuclear Information System (INIS)

    Gryzunov, Y.A.; Syrejshchikova, T.I.; Komarova, M.N.; Misionzhnik, E.Yu.; Uzbekov, M.G.; Molodetskich, A.V.; Dobretsov, G.E.; Yakimenko, M.N.

    2000-01-01

    The properties of serum albumin obtained from donors and from paranoid schizophrenia patients were studied with the fluorescent probe K-35 (N-carboxyphenylimide of dimethylaminonaphthalic acid) and time-resolved fluorescence spectroscopy on the SR beam station of the S-60 synchrotron of the Lebedev Physical Institute. The mean fluorescence quantum yield of K-35 in patients serum was decreased significantly by 25-60% comparing with donors. The analysis of pre-exponential factors of fluorescence decay using 'amplitude standard' method has shown that in patient sera the fraction of K-35 molecules bound with albumin and inaccessible to fluorescence quenchers ('bright' K-35 molecules with τ 1 =8.0±0.4 ns) is 1.2-3 times less than in the donor sera. The fraction of K-35 molecules with partly quenched fluorescence (τ 2 =1.44±0.22 ns) was significantly increased in schizophrenia patients. The results obtained suggest that the properties of binding region in serum albumin molecules of acute paranoid schizophrenia patients change significantly

  16. Effects of single pulse energy on the properties of ceramic coating prepared by micro-arc oxidation on Ti alloy

    International Nuclear Information System (INIS)

    Wang, Jun-Hua; Wang, Jin; Lu, Yan; Du, Mao-Hua; Han, Fu-Zhu

    2015-01-01

    Highlights: • Single pulse energy remarkably influences the properties of ceramic coating prepared by MAO on Ti alloy. • The accumulative time of impulse width is an important parameter in the scientific and rational measurement of the film forming law of ceramic coating. • The ceramic coating thickness approximately linearly increases with the cumulative time of impulse width. • Larger impulse width resulted in higher single pulse energy, film forming rates and thicker ceramic coating thickness. • The effects of single pulse energy on the micro-hardness and phase composition of ceramic coating are not as evident as those of frequency and duty cycle. - Abstract: The effects of single pulse energy on the properties of ceramic coating fabricated on a Ti–6Al–4V alloy via micro-arc oxidation (MAO) in aqueous solutions containing aluminate, phosphate, and some additives are investigated. The thickness, micro-hardness, surface and cross-sectional morphology, surface roughness, and compositions of the ceramic coating are studied using eddy current thickness meter, micro-hardness tester, JB-4C Precision Surface roughness meter, scanning electron microscopy (SEM) and X-ray diffraction (XRD). Single pulse energy remarkably influences the ceramic coating properties. The accumulative time of impulse width is an important parameter in the scientific and rational measurement of the film forming law of ceramic coating. The ceramic coating thickness approximately linearly increases with the cumulative time of impulse width. Larger impulse width resulted in higher single pulse energy, film forming rates and thicker ceramic coating thickness. The sizes of oxide particles, micro-pores and micro-cracks slightly increase with impulse width and single pulse energy. The main surface conversion products generated during MAO process in aqueous solutions containing aluminate are rutile TiO 2 , anatase TiO 2 , and a large amount of Al 2 TiO 5 . The effects of single pulse

  17. Effects of single pulse energy on the properties of ceramic coating prepared by micro-arc oxidation on Ti alloy

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Jun-Hua [Department of Mechanical Engineering, Tsinghua University, Beijing 100084 (China); School of Materials Science and Engineering, Henan University of Science and Technology, Luoyang 471023 (China); Faculty of Mechanical and Electrical Engineering, Kunming University of Science and Technology, Kunming 650500 (China); Wang, Jin [Department of Mechanical Engineering, Tsinghua University, Beijing 100084 (China); Beijing Key Lab of Precision/Ultra-precision Manufacturing Equipments and Control, Beijing 100084 (China); Lu, Yan [School of Materials Science and Engineering, Henan University of Science and Technology, Luoyang 471023 (China); Du, Mao-Hua [Faculty of Mechanical and Electrical Engineering, Kunming University of Science and Technology, Kunming 650500 (China); Han, Fu-Zhu, E-mail: hanfuzhu@mail.tsinghua.edu.cn [Department of Mechanical Engineering, Tsinghua University, Beijing 100084 (China); Beijing Key Lab of Precision/Ultra-precision Manufacturing Equipments and Control, Beijing 100084 (China)

    2015-01-01

    Highlights: • Single pulse energy remarkably influences the properties of ceramic coating prepared by MAO on Ti alloy. • The accumulative time of impulse width is an important parameter in the scientific and rational measurement of the film forming law of ceramic coating. • The ceramic coating thickness approximately linearly increases with the cumulative time of impulse width. • Larger impulse width resulted in higher single pulse energy, film forming rates and thicker ceramic coating thickness. • The effects of single pulse energy on the micro-hardness and phase composition of ceramic coating are not as evident as those of frequency and duty cycle. - Abstract: The effects of single pulse energy on the properties of ceramic coating fabricated on a Ti–6Al–4V alloy via micro-arc oxidation (MAO) in aqueous solutions containing aluminate, phosphate, and some additives are investigated. The thickness, micro-hardness, surface and cross-sectional morphology, surface roughness, and compositions of the ceramic coating are studied using eddy current thickness meter, micro-hardness tester, JB-4C Precision Surface roughness meter, scanning electron microscopy (SEM) and X-ray diffraction (XRD). Single pulse energy remarkably influences the ceramic coating properties. The accumulative time of impulse width is an important parameter in the scientific and rational measurement of the film forming law of ceramic coating. The ceramic coating thickness approximately linearly increases with the cumulative time of impulse width. Larger impulse width resulted in higher single pulse energy, film forming rates and thicker ceramic coating thickness. The sizes of oxide particles, micro-pores and micro-cracks slightly increase with impulse width and single pulse energy. The main surface conversion products generated during MAO process in aqueous solutions containing aluminate are rutile TiO{sub 2}, anatase TiO{sub 2}, and a large amount of Al{sub 2}TiO{sub 5}. The effects of

  18. Remote Raman spectra of benzene obtained from 217 meters using a single 532 nm laser pulse.

    Science.gov (United States)

    Chen, Teng; Madey, John M J; Price, Frank M; Sharma, Shiv K; Lienert, Barry

    2007-06-01

    This report describes a mobile Raman lidar system that has been developed for spectral measurements of samples located remotely at ranges of hundreds of meters. The performance of this system has been quantitatively verified in a lidar calibration experiment using a hard target of standardized reflectance. A new record in detection range was achieved for remote Raman systems using 532 nm laser excitation. Specifically, Raman spectra of liquid benzene were measured with an integration time corresponding to a single 532 nm laser pulse at a distance of 217 meters. The single-shot Raman spectra at 217 meters demonstrated high signal-to-noise ratio and good resolution sufficient for the unambiguous identification of the samples of interest. The transmitter consists of a 20 Hz Nd:YAG laser emitting at 532 nm and 1064 nm and a 178 mm telescope through the use of which allows the system to produce a focused beam at the target location. The receiver consists of a large custom telescope (609 mm aperture) and a Czerny-Turner monochromator equipped with two fast photomultiplier tubes.

  19. Meterwavelength Single-pulse Polarimetric Emission Survey. IV. The Period Dependence of Component Widths of Pulsars

    Science.gov (United States)

    Skrzypczak, Anna; Basu, Rahul; Mitra, Dipanjan; Melikidze, George I.; Maciesiak, Krzysztof; Koralewska, Olga; Filothodoros, Alexandros

    2018-02-01

    The core component width in normal pulsars, with periods (P) > 0.1 s, measured at the half-power point at 1 GHz, has a lower boundary line (LBL) that closely follows the P ‑0.5 scaling relation. This result is of fundamental importance for understanding the emission process and requires extended studies over a wider frequency range. In this paper we have carried out a detailed study of the profile component widths of 123 normal pulsars observed in the Meterwavelength Single-pulse Polarimetric Emission Survey at 333 and 618 MHz. The components in the pulse profile were separated into core and conal classes. We found that at both frequencies, the core, as well as the conal component widths versus period, had a LBL that followed the P ‑0.5 relation with a similar lower boundary. The radio emission in normal pulsars has been observationally shown to arise from a narrow range of heights around a few hundred kilometers above the stellar surface. In the past the P ‑0.5 relation has been considered as evidence for emission arising from last open dipolar magnetic field lines. We show that the P ‑0.5 dependence only holds if the trailing and leading half-power points of the component are associated with the last open field line. In such a scenario we do not find any physical motivation that can explain the P ‑0.5 dependence for both core and conal components as evidence for dipolar geometry in normal pulsars. We believe the period dependence is a result of a currently unexplained physical phenomenon.

  20. Moessbauer spectroscopy with synchrotron radiation

    International Nuclear Information System (INIS)

    Bergmann, U.

    1994-01-01

    The short pulse nature of synchrotron radiation makes it possible to perform Moessbauer spectroscopy in the time domain, i.e. instead of measuring the transmitted intensity time integrated as a function of source/absorber velocity, the intensity of the scattered radiation is measured time differential. The resulting time spectrum is essentially source independent and complications in the data analysis which are related to the radioactive source are completely removed. Furthermore, the large brightness and well defined polarization of the synchrotron radiation can, e.g., speed up the data collection and facilitate studies of polarization phenomena. To illustrate these new spectroscopic possibilities, measurements of the temperature dependence and polarization dependence of forward scattering from alpha - sup 5 sup 7 Fe nuclei are presented and discussed 26 refs., 5 figs. (author)

  1. Micromirror-based manipulation of synchrotron x-ray beams

    Science.gov (United States)

    Walko, D. A.; Chen, Pice; Jung, I. W.; Lopez, D.; Schwartz, C. P.; Shenoy, G. K.; Wang, Jin

    2017-08-01

    Synchrotron beamlines typically use macroscopic, quasi-static optics to manipulate x-ray beams. We present the use of dynamic microelectromechanical systems-based optics (MEMS) to temporally modulate synchrotron x-ray beams. We demonstrate this concept using single-crystal torsional MEMS micromirrors oscillating at frequencies of 75 kHz. Such a MEMS micromirror, with lateral dimensions of a few hundred micrometers, can interact with x rays by operating in grazing-incidence reflection geometry; x rays are deflected only when an x-ray pulse is incident on the rotating micromirror under appropriate conditions, i.e., at an angle less than the critical angle for reflectivity. The time window for such deflections depends on the frequency and amplitude of the MEMS rotation. We demonstrate that reflection geometry can produce a time window of a few microseconds. We further demonstrate that MEMS optics can isolate x rays from a selected synchrotron bunch or group of bunches. With ray-trace simulations we explain the currently achievable time windows and suggest a path toward improvements.

  2. Room-temperature macromolecular serial crystallography using synchrotron radiation

    Directory of Open Access Journals (Sweden)

    Francesco Stellato

    2014-07-01

    Full Text Available A new approach for collecting data from many hundreds of thousands of microcrystals using X-ray pulses from a free-electron laser has recently been developed. Referred to as serial crystallography, diffraction patterns are recorded at a constant rate as a suspension of protein crystals flows across the path of an X-ray beam. Events that by chance contain single-crystal diffraction patterns are retained, then indexed and merged to form a three-dimensional set of reflection intensities for structure determination. This approach relies upon several innovations: an intense X-ray beam; a fast detector system; a means to rapidly flow a suspension of crystals across the X-ray beam; and the computational infrastructure to process the large volume of data. Originally conceived for radiation-damage-free measurements with ultrafast X-ray pulses, the same methods can be employed with synchrotron radiation. As in powder diffraction, the averaging of thousands of observations per Bragg peak may improve the ratio of signal to noise of low-dose exposures. Here, it is shown that this paradigm can be implemented for room-temperature data collection using synchrotron radiation and exposure times of less than 3 ms. Using lysozyme microcrystals as a model system, over 40 000 single-crystal diffraction patterns were obtained and merged to produce a structural model that could be refined to 2.1 Å resolution. The resulting electron density is in excellent agreement with that obtained using standard X-ray data collection techniques. With further improvements the method is well suited for even shorter exposures at future and upgraded synchrotron radiation facilities that may deliver beams with 1000 times higher brightness than they currently produce.

  3. Space Vector Pulse Width Modulation Strategy for Single-Phase Three-Level CIC T-source Inverter

    DEFF Research Database (Denmark)

    Shults, Tatiana E.; Husev, Oleksandr O.; Blaabjerg, Frede

    2016-01-01

    This paper presents a novel space vector pulse-width modulation strategy for a single-phase three-level buck-boost inverter based on an impedance-source network. The case study system is based on T-source inverter with continuous input current. To demonstrate the improved performance of the inver...

  4. A new approach to fabricating magnetic multilayer nanowires by modifying the ac pulse electrodeposition in a single bath

    Science.gov (United States)

    Ramazani, A.; Ghaffari, M.; Almasi Kashi, M.; Kheiry, F.; Eghbal, F.

    2014-09-01

    This work focused on the development of a new single bath technique to fabricate compositionally modulated Co/Cu, CoFe/Cu and Fe/Cu multilayer nanowires in nanoporous alumina templates prepared by the hard and mild anodization methods. The approach was based on ac pulse electrodeposition, employing successive cycles of alternating continuous and pulsed sine waves with designated off-time between pulses and reduction/oxidation voltages. The substantial control over the composition of each segment was achieved by simultaneous change in the off-time between pulses and the ac deposition voltage. The multilayered nature of the nanostructures was substantiated by transmission electron microscopy. Each layer thickness was also nearly uniform, and could be readily adjusted by the number of pulses. The proposed method facilitates the fabrication of various multilayer nanowires in a single bath, which speeds up the fabrication process and is desirable for their application in nanodevices and nanoelectronics. The effect of magnetic layer thickness on the magnetic behaviour was also studied. Decreasing the magnetic layer thickness caused the parallel coercivity and squareness values to approach those measured in the perpendicular direction. The magnetic easy axis changed from parallel to nearly perpendicular to the nanowire axis, depending on the magnetic layers' aspect ratio and shape anisotropies.

  5. Dielectrophoresis study of temporal change in internal conductivity of single CHO cells after electroporation by pulsed electric fields.

    Science.gov (United States)

    Salimi, E; Braasch, K; Butler, M; Thomson, D J; Bridges, G E

    2017-01-01

    Applying sufficiently strong pulsed electric fields to a cell can permeabilize the membrane and subsequently affect its dielectric properties. In this study, we employ a microfluidic dielectrophoresis cytometry technique to simultaneously electroporate and measure the time-dependent dielectric response of single Chinese hamster ovary cells. Using experimental measurements along with numerical simulations, we present quantitative results for the changes in the cytoplasm conductivity of single cells within seconds after exposure to 100  μ s duration pulsed electric fields with various intensities. It is shown that, for electroporation in a medium with conductivity lower than that of the cell's cytoplasm, the internal conductivity of the cell decreases after the electroporation on a time scale of seconds and stronger pulses cause a larger and more rapid decrease. We also observe that, after the electroporation, the cell's internal conductivity is constrained to a threshold. This implies that the cell prevents some of the ions in its cytoplasm from diffusing through the created pores to the external medium. The temporal change in the dielectric response of each individual cell is continuously monitored over minutes after exposure to pulsed electric fields. A time constant associated with the cell's internal conductivity change is observed, which ranges from seconds to tens of seconds depending on the applied pulse intensity. This experimental observation supports the results of numerical models reported in the literature.

  6. Single-pulse observations of the Galactic Center magnetar PSR J1745-2900 at 3.1 GHz

    Science.gov (United States)

    Yan, W. M.; Wang, N.; Manchester, R. N.; Wen, Z. G.; Yuan, J. P.

    2018-02-01

    We report on single-pulse observations of the Galactic Center magnetar PSR J1745-2900 that were made using the Parkes 64-m radio telescope with a central frequency of 3.1 GHz at five observing epochs between 2013 July and August. The shape of the integrated pulse profiles was relatively stable across the five observations, indicating that the pulsar was in a stable state between MJDs 56475 and 56514. This extends the known stable state of this pulsar to 6.8 months. Short term pulse shape variations were also detected. It is shown that this pulsar switches between two emission modes frequently and that the typical duration of each mode is about ten minutes. No giant pulses or subpulse drifting were observed. Apparent nulls in the pulse emission were detected on MJD 56500. Although there are many differences between the radio emission of magnetars and normal radio pulsars, they also share some properties. The detection of mode changing and pulse nulling in PSR J1745-2900 suggests that the basic radio emission process for magnetars and normal pulsars is the same.

  7. Surface microstructure and chemistry of polyimide by single pulse ablation of picosecond laser

    Science.gov (United States)

    Du, Qifeng; Chen, Ting; Liu, Jianguo; Zeng, Xiaoyan

    2018-03-01

    Polyimide (PI) surface was ablated by the single pulse of picosecond laser, and the effects of laser wavelength (λ= 355 nm and 1064 nm) and fluence on surface microstructure and chemistry were explored. Scanning electron microscopy (SEM) analysis found that different surface microstructures, i.e., the concave of concentric ring and the convex of porous circular disk, were generated by 355 nm and 1064 nm picosecond laser ablation, respectively. X-ray photoelectron spectroscopy (XPS) characterization indicated that due to the high peak energy density of picosecond laser, oxygen and nitrogen from the ambient were incorporated into the PI surface mainly in the form of Cdbnd O and Csbnd Nsbnd C groups. Thus, both of the O/C and N/C atomic content ratios increased, but the increase caused by 1064 nm wavelength laser was larger. It inferred that the differences of PI surface microstructures and chemistry resulted from different laser parameters were related to different laser-matter interaction effects. For 355 nm picosecond laser, no obvious thermal features were observed and the probable ablation process of PI was mainly governed by photochemical effect; while for 1064 nm picosecond laser, obvious thermal feature appeared and photothermal effect was thought to be dominant.

  8. Analysis of Dietz's single, rectangular pulse theory for the generation of radiation via photoelectrons

    International Nuclear Information System (INIS)

    Dipp, T.M.

    1993-12-01

    The generation of radiation via photoelectrons induced off of a conducting surface has been analytically modeled and computationally simulated by several researchers. This paper analyzes and compares Dietz's theory predictions with my research to form a unified foundation of consistent, inter-supporting results that should provide confidence in the independently performed basic research and resulting scaling laws and predictions. In doing so, this paper concentrated on Dietz's small-spot, single, rectangular, ''weak'' pulse theory and equations, which involve nonrelativistic, monoenergetic photoelectrons emitted normal to a conducting surface in vacuum. In this paper I: (1) analytically compare Dietz's theory equations with my theory equations, (2) compare Dietz's theoretical scaling laws with my Particle-In-Cell (PIC) code simulation results, and (3) make Dietz's equations easier to use in predicting and optimizing photoelectron-generated radiation. As a result, it is shown that Dietz's equations match my theory's equations in their predicted scaling laws, differing only slightly in their coefficients and unique model parameters. Also, Dietz's equations generally agree with the PIC code results. Finally, optimization analysis showed that theoretical conversion efficiencies for typical real metals can meet and exceed values of 10 -5 if optimal photon energies of 15 to 20 eV are used. Even better efficiencies should be possible if the small-spot constraint is violated as well

  9. In vivo micro-lesion of single dendrite with femtosecond laser pulses

    Science.gov (United States)

    Sacconi, L.; Masi, A.; Diana, G.; Buffelli, M.; Pavone, F. S.

    2007-07-01

    Recently, two-photon microscopy has been used for high spatial resolution imaging of the intact neocortex in living rodents. In this work we used near-IR femtosecond laser pulses for a combination of two-photon microscopy and microdissection on fluorescently-labeled neuronal structures in living mice. Three-dimensional reconstructions of dendrites expressing the green fluorescence protein were made in the cortex of GFP-M and YFP-H transgenic mice. Afterwards, single dendrites were laser-dissected irradiating the structure with a high femtosecond laser energy dose. We report that laser dissection can be performed with micrometric precision and without any visible collateral damage of the surrounding neuronal structures. After laser irradiation, one part of the severed dendrite underwent degeneration and disappeared within 5 hours. Using a chronically implanted glass window, we performed long-term imaging in the area of the dissected dendrite. Images of the long-term morphological changes in the neuronal network after dendritic lesioning will be provided. Laser microdissection of selected structures of the neuronal branching in vivo represents a promising tool for neurobiological research.

  10. Resonant ablation of single-wall carbon nanotubes by femtosecond laser pulses

    International Nuclear Information System (INIS)

    Arutyunyan, N R; Komlenok, M S; Kononenko, V V; Pashinin, V P; Pozharov, A S; Konov, V I; Obraztsova, E D

    2015-01-01

    The thin 50 nm film of bundled arc-discharge single-wall carbon nanotubes was irradiated by femtosecond laser pulses with wavelengths 675, 1350 and 1745 nm corresponding to the absorption band of metallic nanotubes E 11 M , to the background absorption and to the absorption band of semiconducting nanotubes E 11 S , respectively. The aim was to induce a selective removal of nanotubes of specific type from the bundled material. Similar to conducted thermal heating experiments, the effect of laser irradiation results in suppression of all radial breathing modes in the Raman spectra, with preferential destruction of the metallic nanotubes with diameters less than 1.26 nm and of the semiconducting nanotubes with diameters 1.36 nm. However, the etching rate of different nanotubes depends on the wavelength of the laser irradiation. It is demonstrated that the relative content of nanotubes of different chiralities can be tuned by a resonant laser ablation of undesired nanotube fraction. The preferential etching of the resonant nanotubes has been shown for laser wavelengths 675 nm (E 11 M ) and 1745 nm (E 11 S ). (paper)

  11. Investigating emotional top down modulation of ambiguous faces by single pulse TMS on early visual cortices

    Directory of Open Access Journals (Sweden)

    Zachary Adam Yaple

    2016-06-01

    Full Text Available Top-down processing is a mechanism in which memory, context and expectation are used to perceive stimuli. For this study we investigated how emotion content, induced by music mood, influences perception of happy and sad emoticons. Using single pulse TMS we stimulated right occipital face area (rOFA, primary visual cortex (V1 and vertex while subjects performed a face-detection task and listened to happy and sad music. At baseline, incongruent audio-visual pairings decreased performance, demonstrating dependence of emotion while perceiving ambiguous faces. However, performance of face identification decreased during rOFA stimulation regardless of emotional content. No effects were found between Cz and V1 stimulation. These results suggest that while rOFA is important for processing faces regardless of emotion, V1 stimulation had no effect. Our findings suggest that early visual cortex activity may not integrate emotional auditory information with visual information during emotion top-down modulation of faces.

  12. Analysis of single event transient pulse-width in 65 nm commercial radiation-hardened logic cell

    Science.gov (United States)

    Li, Haisong; Wu, Longsheng; Yang, Bo; Jiang, Yihu

    2017-08-01

    With the critical charge reduced to generate a single event effect (SEE) and high working frequency for a nanometer integrated circuit, the single event effect (SET) becomes increasingly serious for high performance SOC and DSP chips. To analyze the radiation-hardened method of SET for the nanometer integrated circuit, the n+ guard ring and p+ guard ring have been adopted in the layout for a 65 nm commercial radiation-hardened standard cell library. The weakest driving capacity inverter cell was used to evaluate the single event transient (SET) pulse-width distribution. We employed a dual-lane measurement circuit to get more accurate SET’s pulse-width. Six kinds of ions, which provide LETs of 12.5, 22.5, 32.5, 42, 63, and 79.5 {MeV}\\cdot {{cm}}2/{mg}, respectively, have been utilized to irradiate the SET test circuit in the Beijing Tandem Accelerator Nuclear Physics National Laboratory. The testing results reveal that the pulse-width of most SETs is shorter than 400 ps in the range of LETeff from 12.5 {MeV}\\cdot {{cm}}2/{mg} to 79.5 {MeV}\\cdot {{cm}}2/{mg} and the pulse-width presents saturation tendency when the effective linear energy transfer (LETeff) value is larger than 40 {MeV}\\cdot {{cm}}2/{mg}. The test results also show that the hardened commercial standard cell’s pulse-width concentrates on 33 to 264 ps, which decreases by 40% compared to the pulse-width of the 65 nm commercial unhardened standard cell.

  13. Experimental Demonstration of the Induction Synchrotron

    International Nuclear Information System (INIS)

    Takayama, Ken; Nakamura, Eiji; Arakida, Yoshio; Iwashita, Taiki; Kono, Tadaaki; Shimosaki, Yoshito; Wake, Masayoshi; Dixit, Tanuja; Otsuka, Kazunori; Torikai, Kota

    2007-01-01

    We report an experimental demonstration of the induction synchrotron, the concept of which has been proposed as a future accelerator for the second generation of neutrino factory or hadron collider. The induction synchrotron supports a superbunch and a superbunch permits more charge to be accelerated while observing the constraints of the transverse space-charge limit. By using a newly developed induction acceleration system instead of radio-wave acceleration devices, a single proton bunch injected from the 500 MeV booster ring and captured by the barrier bucket created by the induction step voltages was accelerated to 6 GeV in the KEK proton synchrotron

  14. The Australian synchrotron; Le synchrotron australien

    Energy Technology Data Exchange (ETDEWEB)

    Farhi, R

    2005-06-15

    This document recalls the historical aspects of the Australian Synchrotron which will be implemented in 2007. It presents then the objectives of this program, the specifications of the ring and the light lines. (A.L.B.)

  15. Object-oriented identification of forested landslides with derivatives of single pulse LiDAR data

    Science.gov (United States)

    Van Den Eeckhaut, Miet; Kerle, Norman; Poesen, Jean; Hervás, Javier

    2012-11-01

    In contrast to the many studies that use expert-based analysis of LiDAR derivatives for landslide mapping in forested terrain, only few studies have attempted to develop (semi-)automatic methods for extracting landslides from LiDAR derivatives. While all these studies are pixel-based, it has not yet been tested whether object-oriented analysis (OOA) could be an alternative. This study investigates the potential of OOA using only single-pulse LiDAR derivatives, such as slope gradient, roughness and curvature to map landslides. More specifically, the focus is on both LiDAR data segmentation and classification of slow-moving landslides in densely vegetated areas, where spectral data do not allow accurate landslide identification. A multistage procedure has been developed and tested in the Flemish Ardennes (Belgium). The procedure consists of (1) image binarization and multiresolution segmentation, (2) classification of landslide parts (main scarps and landslide body segments) and non-landslide features (i.e. earth banks and cropland fields) with supervised support vector machines at the appropriate scale, (3) delineation of landslide flanks, (4) growing of a landslide body starting from its main scarp, and (5) final cleaning of the inventory map. The results obtained show that OOA using LiDAR derivatives allows recognition and characterization of profound morphologic properties of forested deep-seated landslides on soil-covered hillslopes, because more than 90% of the main scarps and 70% of the landslide bodies of an expert-based inventory were accurately identified with OOA. For mountainous areas with bedrock, on the other hand, creation of a transferable model is expected to be more difficult.

  16. Single and Multiple-Selective Excitation Combined with Pulsed Field Gradients

    Science.gov (United States)

    Dalvit, Claudio; Ko, Soo Young; Böhlen, Jean Marc

    1996-02-01

    Applications of selective, multiselective, and semiselective pulses with pulsed field gradients are described. The use of multiple-selective excitation and PFGs for coherence selection in the selective one-dimensional experiments results in spectra devoid of artifacts and with remarkable solvent suppression. Multiple-selective excitation is also employed in an experiment called Multigate, a variant of the well-known WATERGATE experiment, in order to achieve multiple solvent signal suppression. Finally, new pulse sequences are shown for recording pure absorption ω1semiselective PFG NOESY, ROESY, and TOCSY experiments. The merits and limitations of these experiments are discussed.

  17. Femtosecond laser ablation of silver foil with single and double pulses

    CSIR Research Space (South Africa)

    Roberts, DE

    2009-01-01

    Full Text Available ¼ v2 2 ln E Eth � � (7) so that the waist v at the focus and hence the peak F = 2E/pv2 could be found from the slope of r20 versus ln(E). Absolute values of F were estimated to have an uncertainty of �15%. A Michelson interferometer, with one... was used to check the pulse separation for the Dazzler and the zero crossing of the pulse separation from the Michelson interferometer. 4. Results and discussion The average ablation depth per pulse to penetrate a 50 mm thick Ag foil as a function...

  18. Selective generation of two pulse modes in a single all normal dispersion fiber laser oscillator and analysis of their optical characteristics

    Science.gov (United States)

    Kim, S.; Choi, M.; Song, J. Y.; Lee, J. H.; Kim, Y.

    2017-02-01

    Fiber ultrafast pulses such as mode-locked and noise-like pulses have useful optical characteristics for high precision metrology applications. In this study, we develop an ytterbium doped fiber laser with all normal dispersion which can selectively generate two pulse modes, mode-locked and noise-like pulses, by a turn-key system including polarization control and selective detection parts. The spectral and temporal characteristics of two pulses generated from the single oscillator are analyzed and compared with each other through optical spectrum, RF spectrum and autocorrelation. Furthermore, spectral coherence characteristics are verified through interference signals generated by balanced and unbalanced arm interferometers.

  19. Single pulse vibrational Raman scattering by a broadband KrF excimer laser in a hydrogen-air flame

    Science.gov (United States)

    Pitz, Robert W.; Wehrmeyer, Joseph A.; Bowling, J. M.; Cheng, Tsarng-Sheng

    1990-01-01

    Spontaneous vibrational Raman scattering (VRS) is produced by a broadband excimer laser at 248 nm (KrF) in a H2-air flame, and VRS spectra are recorded for lean, stoichiometric, and rich flames. Except at very lean flame conditions, laser-induced fluorescence (LIF) processes interfere with VRS Stokes lines from H2, H2O, and O2. No interference is found for the N2 Stokes and N2 anti-Stokes lines. In a stoichiometric H2/air flame, single-pulse measurements of N2 concentration and temperature (by the VRS Stokes to anti-Stokes ratio) have a relative standard deviation of 7.7 and 10 percent, respectively. These single pulse measurement errors compare well with photon statistics calculations using measured Raman cross sections.

  20. Monolithic Ytterbium All-single-mode Fiber Laser with Direct Fiber-end Delivery of nJ-level Femtosecond Pulses

    DEFF Research Database (Denmark)

    Turchinovich, Dmitry

    2008-01-01

    We demonstrate a monolithic, i.e. without any free-space coupling, all-single-mode passively modelocked Yb-fiber laser, with direct fiber-end delivery of 364−405 fs pulses of 4 nJ pulse energy using a low-loss hollow-core photonic crystal fiber compression.......We demonstrate a monolithic, i.e. without any free-space coupling, all-single-mode passively modelocked Yb-fiber laser, with direct fiber-end delivery of 364−405 fs pulses of 4 nJ pulse energy using a low-loss hollow-core photonic crystal fiber compression....

  1. Single- and multi-pulse formation of surface structures under static femtosecond irradiation

    Science.gov (United States)

    Guillermin, M.; Garrelie, F.; Sanner, N.; Audouard, E.; Soder, H.

    2007-07-01

    Femtosecond surface structure modifications are investigated under irradiation with laser pulses of 150 fs at 800 nm, on copper and silicon. We report sub-wavelength periodic structures formation (ripples) with a periodicity of 500 nm for both materials. These ripples are perpendicular to the laser polarization and can be obtained with only one pulse. The formation of these ripples corresponds to a fluence threshold of 1 J/cm 2 for copper and 0.15 J/cm 2 for silicon. We find several morphologies when more pulses are applied: larger ripples parallel to the polarization are formed with a periodicity of 1 μm and degenerate into a worm-like morphology with a higher number of pulses. In addition, walls of deep holes also show sub-wavelength and large ripples.

  2. Detection of coincident radiations in a single transducer by pulse shape analysis

    Science.gov (United States)

    Warburton, William K [Menlo Park, CA

    2008-03-11

    Pulse shape analysis determines if two radiations are in coincidence. A transducer is provided that, when it absorbs the first radiation produces an output pulse that is characterized by a shorter time constant and whose area is nominally proportional to the energy of the absorbed first radiation and, when it absorbs the second radiation produces an output pulse that is characterized by a longer time constant and whose area is nominally proportional to the energy of the absorbed second radiation. When radiation is absorbed, the output pulse is detected and two integrals are formed, the first over a time period representative of the first time constant and the second over a time period representative of the second time constant. The values of the two integrals are examined to determine whether the first radiation, the second radiation, or both were absorbed in the transducer, the latter condition defining a coincident event.

  3. Production and utilization of synchronized femtosecond electron and laser single pulses

    International Nuclear Information System (INIS)

    Uesaka, M.; Watanabe, T.; Ueda, T.; Nakajima, K.; Kotaki, H.; Ogata, A.

    1997-01-01

    A subpicosecond (700 fs at FWHM) electron pulse from the S-band (2.856 GHz) linear accelerator (linac) of the NERL (Nuclear Engineering Research Laboratory) was synchronized with a femtosecond (100 fs at FWHM) laser pulse from a T 3 (table-top terawatts) laser with a picosecond time whose standard deviation is 3.7 ps. Then we generated a picosecond characteristic X-ray pulse by irradiating through the electron pulse a Cu target (Kα, 8.1 keV, 1.54 A) and obstained the Bragg diffraction from a NaCl ionic monocrystal using a high sensitivity X-ray imaging plate. Further, we discuss its applications to observe lattice vibration of the monocrystal by using the synchronized laser (pump) and X-ray (probe). (orig.)

  4. Multishot versus single-shot pulse sequences in very high field fMRI: a comparison using retinotopic mapping.

    Directory of Open Access Journals (Sweden)

    Jascha D Swisher

    Full Text Available High-resolution functional MRI is a leading application for very high field (7 Tesla human MR imaging. Though higher field strengths promise improvements in signal-to-noise ratios (SNR and BOLD contrast relative to fMRI at 3 Tesla, these benefits may be partially offset by accompanying increases in geometric distortion and other off-resonance effects. Such effects may be especially pronounced with the single-shot EPI pulse sequences typically used for fMRI at standard field strengths. As an alternative, one might consider multishot pulse sequences, which may lead to somewhat lower temporal SNR than standard EPI, but which are also often substantially less susceptible to off-resonance effects. Here we consider retinotopic mapping of human visual cortex as a practical test case by which to compare examples of these sequence types for high-resolution fMRI at 7 Tesla. We performed polar angle retinotopic mapping at each of 3 isotropic resolutions (2.0, 1.7, and 1.1 mm using both accelerated single-shot 2D EPI and accelerated multishot 3D gradient-echo pulse sequences. We found that single-shot EPI indeed led to greater temporal SNR and contrast-to-noise ratios (CNR than the multishot sequences. However, additional distortion correction in postprocessing was required in order to fully realize these advantages, particularly at higher resolutions. The retinotopic maps produced by both sequence types were qualitatively comparable, and showed equivalent test/retest reliability. Thus, when surface-based analyses are planned, or in other circumstances where geometric distortion is of particular concern, multishot pulse sequences could provide a viable alternative to single-shot EPI.

  5. Single Wake Meandering, Advection and Expansion - An analysis using an adapted Pulsed Lidar and CFD LES-ACL simulations

    DEFF Research Database (Denmark)

    Machefaux, Ewan; Larsen, Gunner Chr.; Troldborg, Niels

    2013-01-01

    In this paper, single wake characteristics have been studied both experimentally and numerically. Firstly, the wake is studied experimentally using full-scale measurements from an adapted focused pulsed lidar system, which potentially gives more insight into the wake dynamics as compared to class...... using the EllipSys3D flow solver using Large Eddy Simulation (LES) and Actuator Line Technique (ACL) to model the rotor. Discrepancies due to the uncertainties on the wake advection velocity are observed and discussed....

  6. Single Wake Meandering, Advection and Expansion - An analysis using an adapted Pulsed Lidar and CFD LES-ACL simulations

    DEFF Research Database (Denmark)

    In this paper, single wake characteristics have been studied both experimentally and numerically. Firstly, the wake is studied experimentally using full-scale measurements from an adapted focused pulsed lidar system, which potentially gives more insight into the wake dynamics as compared to class...... using the EllipSys3D flow solver using Large Eddy Simulation (LES) and Actuator Line Technique (ACL) to model the rotor. Discrepancies due to the uncertainties on the wake advection velocity are observed and discussed....

  7. Multidimensional spectroscopy with a single broadband phase-shaped laser pulse

    International Nuclear Information System (INIS)

    Glenn, Rachel; Mukamel, Shaul

    2014-01-01

    We calculate the frequency-dispersed nonlinear transmission signal of a phase-shaped visible pulse to fourth order in the field. Two phase profiles, a phase-step and phase-pulse, are considered. Two dimensional signals obtained by varying the detected frequency and phase parameters are presented for a three electronic band model system. We demonstrate how two-photon and stimulated Raman resonances can be manipulated by the phase profile and sign, and selected quantum pathways can be suppressed

  8. Synchrotron radiation facilities

    CERN Multimedia

    1972-01-01

    Particularly in the past few years, interest in using the synchrotron radiation emanating from high energy, circular electron machines has grown considerably. In our February issue we included an article on the synchrotron radiation facility at Frascati. This month we are spreading the net wider — saying something about the properties of the radiation, listing the centres where synchrotron radiation facilities exist, adding a brief description of three of them and mentioning areas of physics in which the facilities are used.

  9. Synchrotron-driven spallation sources

    CERN Document Server

    Bryant, P J

    1996-01-01

    The use of synchrotrons for pulsed neutron spallation sources is an example of scientific and technological spin-off from the accelerator development for particle physics. Accelerator-driven sources provide an alternative to the continuous-flux, nuclear reactors that currently furnish the majority of neutrons for research and development. Although the present demand for neutrons can be adequately met by the existing reactors, this situation is unlikely to continue due to the increasing severity of safety regulations and the declared policies of many countries to close down their reactors within the next decade or so. Since the demand for neutrons as a research tool is, in any case,expected to grow, there has been a corresponding interest in sources that are synchrotron-driven or linac-driven with a pulse compression ring and currently several design studies are being made. These accelerator-driven sources also have the advantage of a time structure with a high peak neutron flux. The basic requirement is for a...

  10. Single mode operation in a pulsed Ti:sapphire laser oscillator with a grazing-incidence four-mirror cavity

    CERN Document Server

    Ko, D K; Binks, D J; Gloster, L A W; King, T A

    1998-01-01

    We demonstrate stable single mode operation in a pulsed Ti:sapphire laser oscillator with a novel grazing-incidence four-mirror coupled cavity. This cavity consists of a grating, a gain medium, and four mirrors and, therefore, has a four-arm interferometer configuration. Through the interferometric effect, we could suppress the adjacent modes and obtain stable single mode operation with a bandwidth of < 200 MHz. We also have developed a general analysis of the laser modes and the threshold conditions for configuration and the experimental results agree well with the theoretical predictions.

  11. High-pressure single-crystal synchrotron X-ray diffraction of kainite (KMg(SO4) Cl 3H2O)

    Science.gov (United States)

    Nazzareni, S.; Comodi, P.; Hanfland, M.

    2018-03-01

    Kainite (KMg(SO4) Cl 3H2O) is a "mixed-salt" sulfate from the group of evaporitic minerals more soluble than Ca-sulfate hydrate and NaCl. The compressibility and structural modifications of monoclinic (sp. gr. C2/m) kainite up to a pressure of 14 GPa were studied by high-pressure single-crystal synchrotron X-ray diffraction. Kainite remains stable over the investigated pressure range and no phase transition was recognised. The bulk modulus is K 0 = 31.6 (1) GPa, with K' fixed to 4, as obtained by fitting the P-volume data with a second-order Birch-Murnaghan EoS (BM2); instead of using a BM3 EoS, we obtained K 0 = 32.2(5) GPa, K' =3.8 (1). The linear moduli calculated for the lattice parameters fitting the data with a BM3 EoS are for a-axis M 0a = 117(4) GPa, Mpa = 11(1), for b-axis M 0b = 113(2) GPa, Mpc = 8.6(5), and c-axis M 0c = 68.2(3) GPa, Mpc = 14(1). Structure refinements showed a strong compression of the K polyhedra and in particular K(1) and K(3) polyhedra have similar polyhedral bulk moduli: K 0K(1) = 20.8(7) GPa, K'=4.8(3); K 0K(2) = 29(1) GPa, K'=8.1(6); K 0K(3) = 26(1) GPa, K'=4.2(4). The most compressible bond distances are K(1)-Cl(2) with a shortening of about 13%, K(1)-Cl(1) with a shortening of about 10%, K(3)-Ow(6) and K(3)-O8(B) both with a shortening of 9%. S-tetrahedra are almost incompressible and Mg-octahedra bulk moduli are K 0Mg(2) = 102(4) GPa, and K 0Mg(4) = 72(1) GPa, K 0Mg(1) = 41(4) GPa K'= 8.9(1.7), and K 0Mg(3) = 65(5) GPa K'= 10(2). The strain tensor analysis indicates that the most compressible direction of the kainite monoclinic structure is oriented 29.7(2)° from the c-axis in the (0 1 0) plane. The shortening of the K(1)-K(2) distance (from 4.219(4) Å at ambient P to 3.521(7) Å at 11.9 GPa) and the different compressibilities of the octahedra/tetrahedra may explain why the stiffer direction of kainite is in the a-c plane approximatively along the direction where K(1)-K(2) and Mg(4)-Mg(3)-Mg(4) polyhedra align. This may

  12. Single attosecond pulse generation in an orthogonally polarized two-color laser field combined with a static electric field

    International Nuclear Information System (INIS)

    Xia Changlong; Zhang Gangtai; Wu Jie; Liu Xueshen

    2010-01-01

    We investigate theoretic high-order harmonic generation and single attosecond pulse generation in an orthogonally polarized two-color laser field, which is synthesized by a mid-infrared (IR) pulse (12.5 fs, 2000 nm) in the y component and a much weaker (12 fs, 800 nm) pulse in the x component. We find that the width of the harmonic plateau can be extended when a static electric field is added in the y component. We also investigate emission time of harmonics in terms of a time-frequency analysis to illustrate the physical mechanism of high-order harmonic generation. We calculate the ionization rate using the Ammosov-Delone-Krainov model and interpret the variation of harmonic intensity for different static electric field strengths. When the ratio of strengths of the static and the y-component laser fields is 0.1, a continuous harmonic spectrum is formed from 220 to 420 eV. By superposing a properly selected range of the harmonic spectrum from 300 to 350 eV, an isolated attosecond pulse with a duration of about 75 as is obtained, which is near linearly polarized.

  13. Saturated multikilovolt x-ray amplification with Xe clusters: single-pulse observation of Xe(L) spectral hole burning

    International Nuclear Information System (INIS)

    Borisov, Alex B; Davis, Jack; Song, Xiangyang; Koshman, Yevgeniya; Dai Yang; Boyer, Keith; Rhodes, Charles K

    2003-01-01

    Single-pulse measurements of spectral hole burning of Xe(L) 3d → 2p hollow atom transition arrays observed from a self-trapped plasma channel provide new information on the dynamics of saturated amplification in the λ ∼ 2.8-2.9 A region. The spectral hole burning on transitions in the Xe 34+ and Xe 35+ arrays reaches full suppression of the spontaneous emission and presents a corresponding width Δ h-bar ω x ∼ = 60 eV, a value adequate for efficient amplification of multikilovolt x-ray pulses down to a limiting length τ x ∼ 30 as. The depth of the suppression at 2.86 A indicates that the gain-to-loss ratio is ≥10. An independent determination of the x-ray pulse energy from damage produced on the surface of a Ti foil in the far field of the source gives a pulse energy of 20-30 μJ, a range that correlates well with the observation of the spectral hole burning and indicates an overall extraction efficiency of ∼10%. (letter to the editor)

  14. Quantitative determination of wear metals in engine oils using LIBS: The use of paper substrates and a comparison between single- and double-pulse LIBS

    International Nuclear Information System (INIS)

    A comparison between single- and double-pulse LIBS for the quantitative elemental analysis of used engine oils has been performed. Paper substrates have been utilised for the analysis and are shown to provide better limits of detection (LODs), no splashing and easier sample handling compared to the previously reported experiments using laminar liquid jets and static liquid surfaces. Single-pulse LIBS analysis of oil on paper substrates has had on average 2x better LODs than was obtained using flowing liquid jets, while double-pulse LIBS showed 4x improvement. Single-pulse LIBS has been found preferable for the analysis, as the use of an additional laser in double-pulse LIBS yielded only a minor improvement while adding substantially to the complexity and cost of the system

  15. High-energy synchrotron X-ray radiography of shock-compressed materials

    Science.gov (United States)

    Rutherford, Michael E.; Chapman, David J.; Collinson, Mark A.; Jones, David R.; Music, Jasmina; Stafford, Samuel J. P.; Tear, Gareth R.; White, Thomas G.; Winters, John B. R.; Drakopoulos, Michael; Eakins, Daniel E.

    2015-06-01

    This presentation will discuss the development and application of a high-energy (50 to 250 keV) synchrotron X-ray imaging method to study shock-compressed, high-Z samples at Beamline I12 at the Diamond Light Source synchrotron (Rutherford-Appleton Laboratory, UK). Shock waves are driven into materials using a portable, single-stage gas gun designed by the Institute of Shock Physics. Following plate impact, material deformation is probed in-situ by white-beam X-ray radiography and complimentary velocimetry diagnostics. The high energies, large beam size (13 x 13 mm), and appreciable sample volumes (~ 1 cm3) viable for study at Beamline I12 compliment existing in-house pulsed X-ray capabilities and studies at the Dynamic Compression Sector. The authors gratefully acknowledge the ongoing support of Imperial College London, EPSRC, STFC and the Diamond Light Source, and AWE Plc.

  16. Synchrotron radiation sources

    Energy Technology Data Exchange (ETDEWEB)

    van Steenbergen, A.

    1979-01-01

    As a result of the exponential growth of the utilization of synchrotron radiation for research in the domain of the material sciences, atomic and molecular physics, biology and technology, a major construction activity has been generated towards new dedicated electron storage rings, designed optimally for synchrotron radiation applications, also, expansion programs are underway at the existing facilities, such as DORIS, SPEAR, and VEPP. In this report the basic properties of synchrotron radiation will be discussed, a short overview will be given of the existing and new facilities, some aspects of the optimization of a structure for a synchrotron radiation source will be discussed and the addition of wigglers and undulators for spectrum enhancement will be described. Finally, some parameters of an optimized synchrotron radiation source will be given.

  17. Synchrotron radiation from protons

    International Nuclear Information System (INIS)

    Dutt, S.K.

    1992-12-01

    Synchrotron radiation from protons, though described by the same equations as the radiation from electrons, exhibits a number of interesting features on account of the parameters reached in praxis. In this presentation, we shall point out some of the features relating to (i) normal synchrotron radiation from dipoles in proton machines such as the High Energy Booster and the Superconducting Super Collider; (ii) synchrotron radiation from short dipoles, and its application to light monitors for proton machines, and (iii) synchrotron radiation from undulators in the limit when, the deflection parameter is much smaller than unity. The material for this presentation is taken largely from the work of Hofmann, Coisson, Bossart, and their collaborators, and from a paper by Kim. We shall emphasize the qualitative aspects of synchrotron radiation in the cases mentioned above, making, when possible, simple arguments for estimating the spectral and angular properties of the radiation. Detailed analyses can be found in the literature

  18. Nanofluidic Devices with Two Pores in Series for Resistive-Pulse Sensing of Single Virus Capsids

    DEFF Research Database (Denmark)

    Harms, Zachary D.; Mogensen, Klaus Bo; Rodrigues de Sousa Nunes, Pedro André

    2011-01-01

    We report fabrication and characterization of nanochannel devices with two nanopores in series for resistive-pulse sensing of hepatitis B virus (HBV) capsids. The nanochannel and two pores are patterned by electron beam lithography between two microchannels and etched by reactive ion etching...

  19. Design and Construction of an Autonomous Low-Cost Pulse Height Analyzer and a Single Channel Analyzer for Moessbauer Spectroscopy

    International Nuclear Information System (INIS)

    Velasquez, A.A.; Trujillo, J.M.; Morales, A.L.; Tobon, J.E.; Gancedo, J.R.; Reyes, L.

    2005-01-01

    A multichannel analyzer (MCA) and a single channel-analyzer (SCA) for Moessbauer spectrometry application have been designed and built. Both systems include low-cost digital and analog components. A microcontroller manages, either in PHA or MCS mode, the data acquisition, data storage and setting of the pulse discriminator limits. The user can monitor the system from an external PC through the serial port with the RS232 communication protocol. A graphic interface made with the LabVIEW software allows the user to adjust digitally the lower and upper limits of the pulse discriminator, and to visualize as well as save the PHA spectra in a file. The system has been tested using a 57Co radioactive source and several iron compounds, yielding satisfactory results. The low cost of its design, construction and maintenance make this equipment an attractive choice when assembling a Moessbauer spectrometer

  20. Self-organized single crystal mixed magnetite/cobalt ferrite films grown by infrared pulsed-laser deposition

    Energy Technology Data Exchange (ETDEWEB)

    Figuera, Juan de la, E-mail: juan.delafiguera@iqfr.csic.es [Instituto de Química Física “Rocasolano”, CSIC, Madrid E-28006 (Spain); Quesada, Adrián [Instituto de Cerámica y Vidrio, CSIC, Madrid E-28049 (Spain); Martín-García, Laura; Sanz, Mikel; Oujja, Mohamed; Rebollar, Esther; Castillejo, Marta [Instituto de Química Física “Rocasolano”, CSIC, Madrid E-28006 (Spain); Prieto, Pilar; Muñoz-Martín, Ángel [Universidad Autónoma de Madrid, E-28049 (Spain); Aballe, Lucía [Alba Synchrotron Light Facility, CELLS, Barcelona (Spain); Marco, José F. [Instituto de Química Física “Rocasolano”, CSIC, Madrid E-28006 (Spain)

    2015-12-30

    Highlights: • Infrared pulsed deposition is used to grow single crystal mixed magnetite-cobalt ferrite films. • Distinct topography with two mound types on the surface of the film. • Suggested origin of segregation into two phases is oxygen deficiency during growth. • Mössbauer is required to quantify the two components. - Abstract: We have grown mixed magnetite/cobalt ferrite epitaxial films on SrTiO{sub 3} by infrared pulsed-laser deposition. Diffraction experiments indicate epitaxial growth with a relaxed lattice spacing. The films are flat with two distinct island types: nanometric rectangular mounds in two perpendicular orientations, and larger square islands, attributed to the two main components of the film as determined by Mössbauer spectroscopy. The origin of the segregation is suggested to be the oxygen-deficiency during growth.

  1. A portable high-field pulsed-magnet system for single-crystal x-ray scattering studies

    International Nuclear Information System (INIS)

    Islam, Zahirul; Lang, Jonathan C.; Ruff, Jacob P. C.; Ross, Kathryn A.; Gaulin, Bruce D.; Nojiri, Hiroyuki; Matsuda, Yasuhiro H.; Qu Zhe

    2009-01-01

    We present a portable pulsed-magnet system for x-ray studies of materials in high magnetic fields (up to 30 T). The apparatus consists of a split-pair of minicoils cooled on a closed-cycle cryostat, which is used for x-ray diffraction studies with applied field normal to the scattering plane. A second independent closed-cycle cryostat is used for cooling the sample to near liquid helium temperatures. Pulsed magnetic fields (∼1 ms in total duration) are generated by discharging a configurable capacitor bank into the magnet coils. Time-resolved scattering data are collected using a combination of a fast single-photon counting detector, a multichannel scaler, and a high-resolution digital storage oscilloscope. The capabilities of this instrument are used to study a geometrically frustrated system revealing strong magnetostrictive effects in the spin-liquid state.

  2. Gold nanoshell photomodification under a single-nanosecond laser pulse accompanied by color-shifting and bubble formation phenomena

    International Nuclear Information System (INIS)

    Akchurin, Garif; Khlebtsov, Boris; Akchurin, Georgy; Tuchin, Valery; Zharov, Vladimir; Khlebtsov, Nikolai

    2008-01-01

    Laser-nanoparticle interaction is crucial for biomedical applications of lasers and nanotechnology to the treatment of cancer or pathogenic microorganisms. We report on the first observation of laser-induced coloring of gold nanoshell solution after a one nanosecond pulse and an unprecedentedly low bubble formation (as the main mechanism of cancer cell killing) threshold at a laser fluence of about 4 mJ cm -2 , which is safe for normal tissue. Specifically, silica/gold nanoshell (140/15 nm) suspensions were irradiated with a single 4 ns (1064 nm) or 8 ns (900 nm) laser pulse at fluences ranging from 0.1 mJ cm -2 to 50 J cm -2 . Solution red coloring was observed by the naked eye confirmed by blue-shifting of the absorption spectrum maximum from the initial 900 nm for nanoshells to 530 nm for conventional colloidal gold nanospheres. TEM images revealed significant photomodification of nanoparticles including complete fragmentation of gold shells, changes in silica core structure, formation of small 20-30 nm isolated spherical gold nanoparticles, gold nanoshells with central holes, and large and small spherical gold particles attached to a silica core. The time-resolved monitoring of bubble formation phenomena with the photothermal (PT) thermolens technique demonstrated that after application of a single 8 ns pulse at fluences 5-10 mJ cm -2 and higher the next pulse did not produce any PT response, indicating a dramatic decrease in absorption because of gold shell modification. We also observed a dependence of the bubble expansion time on the laser energy with unusually very fast PT signal rising (∼3.5 ns scale at 0.2 J cm -2 ). Application of the observed phenomena to medical applications is discussed, including a simple visual color test for laser-nanoparticle interaction

  3. A biosafety evaluation of synchrotron radiation X-ray to skin and bone marrow: single dose irradiation study of rats and macaques.

    Science.gov (United States)

    Lu, Yifan; Tang, Guanghui; Lin, Hui; Lin, Xiaojie; Jiang, Lu; Yang, Guo-Yuan; Wang, Yongting

    2017-06-01

    Very limited experimental data is available regarding the safe dosages related to synchrotron radiation (SR) procedures. We used young rats and macaques to address bone marrow and skin tolerance to various doses of synchrotron radiation. Rats were subjected to 0, 0.5, 2.5, 5, 25 or 100 Gy local SR X-ray irradiation at left hind limb. Rat blood samples were analyzed at 2-90 days after irradiation. The SR X-ray irradiated skin and tibia were sectioned for morphological examination. For non-human primate study, three male macaques were subjected to 0.5 or 2.5 Gy SR X-ray on crus. Skin responses of macaques were observed. All rats that received SR X-ray irradiation doses greater than 2.5 Gy experienced hair loss and bone-growth inhibition, which were accompanied by decreased number of follicles, thickened epidermal layer, and decreased density of bone marrow cells (p X-ray but showed significant hair loss when the dose was raised above 2.5 Gy. The safety threshold doses of SR X-ray for rat skin, bone marrow and macaque skin are between 0.5 and 2.5 Gy. Our study provided essential information regarding the biosafety of SR X-ray irradiation.

  4. Construction of a single/multiple wavelength RZ optical pulse source at 40 GHz by use of wavelength conversion in a high-nonlinearity DSF-NOLM

    DEFF Research Database (Denmark)

    Yu, Jianjun; Yujun, Qian; Jeppesen, Palle

    2001-01-01

    A single or multiple wavelength RZ optical pulse source at 40 GHz is successfully obtained by using wavelength conversion in a nonlinear optical loop mirror consisting of high nonlinearity-dispersion shifted fiber.......A single or multiple wavelength RZ optical pulse source at 40 GHz is successfully obtained by using wavelength conversion in a nonlinear optical loop mirror consisting of high nonlinearity-dispersion shifted fiber....

  5. Rapid-Cycling Synchrotron extraction-kicker magent-drive system

    International Nuclear Information System (INIS)

    Suddeth, D.E.; Volk, G.J.

    1981-01-01

    The Rapid-Cycling Synchrotron (RCS) accelerator of the Intense Pulsed Neutron Source-I (IPNS-I) at Argonne National Laboratory utilizes a fast kicker magnet to provide single-turn extraction for a 500-MeV proton beam at a 30 Hz rate. The single-turn, 0.89-m-long ferrite magnet is broken up into two identical cells with four individual windings. Each winding requires a 4863-A magnetizing current into a 7.0-Ω load with a rise time of less than 100 ns and a flattop of about 140 ns. Pulse forming network (PFN) charging and switching techniques along with the components used will be described

  6. High-energy electron emission from metallic nano-tips driven by intense single-cycle terahertz pulses

    Science.gov (United States)

    Li, Sha; Jones, R. R.

    2016-01-01

    Electrons ejected from atoms and subsequently driven to high energies in strong laser fields enable techniques from attosecond pulse generation to imaging with rescattered electrons. Analogous processes govern strong-field electron emission from nanostructures, where long wavelength radiation and large local field enhancements hold the promise for producing electrons with substantially higher energies, allowing for higher resolution time-resolved imaging. Here we report on the use of single-cycle terahertz pulses to drive electron emission from unbiased nano-tips. Energies exceeding 5 keV are observed, substantially greater than previously attained at higher drive frequencies. Despite large differences in the magnitude of the respective local fields, we find that the maximum electron energies are only weakly dependent on the tip radius, for 10 nmsingle-cycle nature of the field, the high-energy electron emission is predicted to be confined to a single burst, potentially enabling a variety of applications. PMID:27830701

  7. Single-pulse characteristics of the Xe(L) amplifier on the Xe35+ (3d→2p) transition array at λ ≅ 2.86 A

    International Nuclear Information System (INIS)

    Borisov, Alex B; Song Xiangyang; Zhang Ping; McCorkindale, John C; Khan, Shahab F; De Jonghe, Richard; Poopalasingam, Sankar; Zhao, Ji; Boyer, Keith; Rhodes, Charles K

    2006-01-01

    The triple comparison of (1) single-pulse spectral data, recorded with a CCD-equipped von Hamos spectrometer both axially and transversely; (2) axially measured time-integrated spectra registered on a film and (3) single-pulse x-ray images of the morphology of the self-trapped plasma channel, recorded simultaneously with the single-pulse spectra, establishes several leading characteristics of the saturated amplification observed on the Xe 35+ transition array at λ ≅ 2.86 A. The chief findings are (α) absolute positive correlation of amplification with the formation of a plasma channel, (β) a perfect spectral match of the amplified transitions in the comparison of axially recorded single-pulse and time-integrated film data and (γ) exact spectral correspondence of both the axially registered single-pulse and time-integrated film data with single-pulse transversely measured spectra exhibiting deep spectral hole burning at the position of the Xe 35+ array. (letter to the editor)

  8. Determination of nanogram quantities of osmium-labeled single stranded DNA by differential pulse stripping voltammetry

    Czech Academy of Sciences Publication Activity Database

    Kizek, René; Havran, Luděk; Fojta, Miroslav; Paleček, Emil

    2002-01-01

    Roč. 55, 1/2 (2002), s. 199-121 ISSN 1567-5394 R&D Projects: GA ČR GV204/97/K084; GA ČR GA204/00/D049; GA AV ČR IAA4004108 Institutional research plan: CEZ:AV0Z5004920 Keywords : differential pulse stripping voltammetry * microdetermination of DNA * chemical modification of DNA Subject RIV: BO - Biophysics Impact factor: 1.463, year: 2002

  9. Pulsed neutron measurement of single and two-phase liquid flow

    International Nuclear Information System (INIS)

    Kehler, P.

    1978-01-01

    Use of radioactive tracers for flow velocity measurements is well developed and documented. Measurement techniques involving pulsed sources of fast (14 MeV) neutrons for in-situ production of tracers can be considered as extensions of the old methods. Improvements offered by these Pulsed Neutron Activation (PNA) techniques over conventional radioisotope techniques are (1) non-intrusion into the system, (2) easier introduction and better mixing of the tracer, and (3) no requirement to handle large amounts of relatively long lived radioactive materials. Just as in conventional tracer techniques, flow velocity measurements by PNA methods can be based on the transit-time or the total-count method. A very significant difference of the PNA technique from conventional methods is that the induced activity is proportional to the density of the fluid, and that PNA techniques can be used for density measurements (of two-phase flows) in addition to flow velocity measurement. Original equations were derived that relate experimental data to the mass flow velocity and the average density. The accuracy of these equations is not effected by the flow regime. Experimental results are presented for tests performed on liquid sodium loops, on air--water loops, on the EBR-II reactor and on the LOFT reactor. Current instrumentation development programs (detectors, pulsed neutron sources) are discussed

  10. Quantifying pulsed electric field-induced membrane nanoporation in single cells.

    Science.gov (United States)

    Moen, Erick K; Ibey, Bennett L; Beier, Hope T; Armani, Andrea M

    2016-11-01

    Plasma membrane disruption can trigger a host of cellular activities. One commonly observed type of disruption is pore formation. Molecular dynamic (MD) simulations of simplified lipid membrane structures predict that controllably disrupting the membrane via nano-scale poration may be possible with nanosecond pulsed electric fields (nsPEF). Until recently, researchers hoping to verify this hypothesis experimentally have been limited to measuring the relatively slow process of fluorescent markers diffusing across the membrane, which is indirect evidence of nanoporation that could be channel-mediated. Leveraging recent advances in nonlinear optical microscopy, we elucidate the role of pulse parameters in nsPEF-induced membrane permeabilization in live cells. Unlike previous techniques, it is able to directly observe loss of membrane order at the onset of the pulse. We also develop a complementary theoretical model that relates increasing membrane permeabilization to membrane pore density. Due to the significantly improved spatial and temporal resolution possible with our imaging method, we are able to directly compare our experimental and theoretical results. Their agreement provides substantial evidence that nanoporation does occur and that its development is dictated by the electric field distribution. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. Linear optics survey of the BESSY II booster synchrotron

    Energy Technology Data Exchange (ETDEWEB)

    Volz, Paul; Jankowiak, Andreas; Ries, Markus [Helmholtz-Zentrum Berlin, Berlin (Germany)

    2016-07-01

    The proposed VSR upgrade for the BESSY II storage ring features photon pulses as short as 1.7 ps. The current injection system (linac, booster synchrotron, and transfer line) cannot provide electron bunches short enough to meet the required injection efficiency for TopUp operation. This contribution investigates if the momentum compaction factor of the booster synchrotron can be decreased just by changing the quadrupole strengths in the existing booster synchrotron lattice. It was found that by splitting the two quadrupole families into four the momentum compaction factor can be reduced.

  12. Power supplies for the injector synchrotron quadrupoles and sextupoles

    International Nuclear Information System (INIS)

    Fathizadeh, M.

    1995-01-01

    This light source note will describe the power supplies for the injector synchrotron quadrupole and sextupole magnets. The injector synchrotron has two families of quadrupole magnets. Each family consists of 40 quadrupole magnets connected in series. These magnets are energized by two phase-controlled, 12-pulse power supplies. Therefore, each power supply will be rated to deliver the necessary power to only 40 quadrupole magnets. The two families of sextupole magnets in the injector synchrotron each consists of 32 sextupole magnets connected in series, powered by a phase-controlled power supply. Thus, each power supply shall be capable of delivering power to only 32 sextupole magnets

  13. National Synchrotron Light Source

    International Nuclear Information System (INIS)

    Hulbert, S.L.; Lazarz, N.M.

    1991-04-01

    This report discussion research being conducted at the National Synchrotron light source. In particular, this report contains operations summaries; symposia, workshops, and projects; NSLS highlights; and abstracts of science at the NSLS

  14. The World of Synchrotrons

    Indian Academy of Sciences (India)

    -particles when .... ence, high-vacuum environment, etc.) make synchrotron radiation a very powerful tool for a variety of .... one of the leading countries along with the United States and the European Union in accelerator-based science re-.

  15. Polymer optical fiber Bragg grating inscription with a single UV laser pulse

    DEFF Research Database (Denmark)

    Pospori, Andreas; Marques, A.T.; Bang, Ole

    2017-01-01

    laser pulse with a duration of 15 ns, which provide energy density of 974 mJ/cm2, is adequate to introduce a refractive index change of 0.74×10-4 in the fiber core. After the exposure, the reflectivity of the grating increases for a few minutes following a second order exponential saturation...... of the grating structures. Optimizing the irradiation conditions and the material chemical composition, a higher refractive index change in the fiber core is feasible. This demonstration significantly improves the potential for commercial exploitation of the technology....

  16. Surface modification of polymethylmethacrylate irradiated with 60 fs single laser pulses

    Czech Academy of Sciences Publication Activity Database

    Klinger, D.; Sobierajski, R.; Nietubyc, R.; Krzywinski, J.; Pelka, J.; Juha, Libor; Jurek, M.; Zymierska, D.; Guizard, S.; Merdji, H.

    2009-01-01

    Roč. 78, Suppl. 10 (2009), S71-S74 ISSN 0969-806X R&D Projects: GA AV ČR KAN300100702; GA MŠk LC510; GA MŠk(CZ) LC528; GA MŠk LA08024; GA AV ČR IAA400100701 Institutional research plan: CEZ:AV0Z10100523 Keywords : polymethylmethacrylate (PMMA) * IR laser ablation * femtosecond laser pulse Subject RIV: BH - Optics, Masers, Lasers Impact factor: 1.149, year: 2009

  17. Empirical modeling of single-wake advection and expansion using full-scale pulsed lidar-based measurements

    DEFF Research Database (Denmark)

    Machefaux, Ewan; Larsen, Gunner Chr.; Troldborg, Niels

    2015-01-01

    and to obtain an estimate of the wake expansion in a fixed frame of reference. A comparison shows good agreement between the measured average expansion and the Computational Fluid Dynamics (CFD) large eddy simulation–actuator line computations. Frandsen’s expansion model seems to predict the wake expansion......In the present paper, single-wake dynamics have been studied both experimentally and numerically. The use of pulsed lidar measurements allows for validation of basic dynamic wake meandering modeling assumptions. Wake center tracking is used to estimate the wake advection velocity experimentally...... fairly well in the far wake but lacks accuracy in the outer region of the near wake. An empirical relationship, relating maximum wake induction and wake advection velocity, is derived and linked to the characteristics of a spherical vortex structure. Furthermore, a new empirical model for single...

  18. Reaction-time-resolved measurements of laser-induced fluorescence in a shock tube with a single laser pulse

    Science.gov (United States)

    Zabeti, S.; Fikri, M.; Schulz, C.

    2017-11-01

    Shock tubes allow for the study of ultra-fast gas-phase reactions on the microsecond time scale. Because the repetition rate of the experiments is low, it is crucial to gain as much information as possible from each individual measurement. While reaction-time-resolved species concentration and temperature measurements with fast absorption methods are established, conventional laser-induced fluorescence (LIF) measurements with pulsed lasers provide data only at a single reaction time. Therefore, fluorescence methods have rarely been used in shock-tube diagnostics. In this paper, a novel experimental concept is presented that allows reaction-time-resolved LIF measurements with one single laser pulse using a test section that is equipped with several optical ports. After the passage of the shock wave, the reactive mixture is excited along the center of the tube with a 266-nm laser beam directed through a window in the end wall of the shock tube. The emitted LIF signal is collected through elongated sidewall windows and focused onto the entrance slit of an imaging spectrometer coupled to an intensified CCD camera. The one-dimensional spatial resolution of the measurement translates into a reaction-time-resolved measurement while the species information can be gained from the spectral axis of the detected two-dimensional image. Anisole pyrolysis was selected as the benchmark reaction to demonstrate the new apparatus.

  19. Storage of multiple single-photon pulses emitted from a quantum dot in a solid-state quantum memory.

    Science.gov (United States)

    Tang, Jian-Shun; Zhou, Zong-Quan; Wang, Yi-Tao; Li, Yu-Long; Liu, Xiao; Hua, Yi-Lin; Zou, Yang; Wang, Shuang; He, De-Yong; Chen, Geng; Sun, Yong-Nan; Yu, Ying; Li, Mi-Feng; Zha, Guo-Wei; Ni, Hai-Qiao; Niu, Zhi-Chuan; Li, Chuan-Feng; Guo, Guang-Can

    2015-10-15

    Quantum repeaters are critical components for distributing entanglement over long distances in presence of unavoidable optical losses during transmission. Stimulated by the Duan-Lukin-Cirac-Zoller protocol, many improved quantum repeater protocols based on quantum memories have been proposed, which commonly focus on the entanglement-distribution rate. Among these protocols, the elimination of multiple photons (or multiple photon-pairs) and the use of multimode quantum memory are demonstrated to have the ability to greatly improve the entanglement-distribution rate. Here, we demonstrate the storage of deterministic single photons emitted from a quantum dot in a polarization-maintaining solid-state quantum memory; in addition, multi-temporal-mode memory with 1, 20 and 100 narrow single-photon pulses is also demonstrated. Multi-photons are eliminated, and only one photon at most is contained in each pulse. Moreover, the solid-state properties of both sub-systems make this configuration more stable and easier to be scalable. Our work will be helpful in the construction of efficient quantum repeaters based on all-solid-state devices.

  20. Investigation of the particle size distribution of the ejected material generated during the single femtosecond laser pulse ablation of aluminium

    International Nuclear Information System (INIS)

    Wu, Han; Zhang, Nan; Zhu, Xiaonong

    2014-01-01

    Highlights: • Single 50 fs laser pulse ablation of an aluminium target in vacuum is investigated in our experiments. • Nanoparticles with large radii of several hundred nanometers are observed. • The nanoparticles are most likely from the mechanical tensile stress relaxation. - Abstract: Single femtosecond laser pulses are employed to ablate an aluminium target in vacuum, and the particle size distribution of the ablated material deposited on a mica substrate is examined with atomic force microscopy (AFM). The recorded AFM images show that these particles have a mean radius of several tens of nanometres. It is also determined that the mean radius of these deposited nanoparticles increases when the laser fluence at the aluminium target increases from 0.44 J/cm 2 to 0.63 J/cm 2 . The mechanism of the laser-induced nanoparticle generation is thought to be photomechanical tensile stress relaxation. Raman spectroscopy measurements confirm that the nanoparticles thus produced have the same structure as the bulk aluminium

  1. Storage of multiple single-photon pulses emitted from a quantum dot in a solid-state quantum memory

    Science.gov (United States)

    Tang, Jian-Shun; Zhou, Zong-Quan; Wang, Yi-Tao; Li, Yu-Long; Liu, Xiao; Hua, Yi-Lin; Zou, Yang; Wang, Shuang; He, De-Yong; Chen, Geng; Sun, Yong-Nan; Yu, Ying; Li, Mi-Feng; Zha, Guo-Wei; Ni, Hai-Qiao; Niu, Zhi-Chuan; Li, Chuan-Feng; Guo, Guang-Can

    2015-01-01

    Quantum repeaters are critical components for distributing entanglement over long distances in presence of unavoidable optical losses during transmission. Stimulated by the Duan–Lukin–Cirac–Zoller protocol, many improved quantum repeater protocols based on quantum memories have been proposed, which commonly focus on the entanglement-distribution rate. Among these protocols, the elimination of multiple photons (or multiple photon-pairs) and the use of multimode quantum memory are demonstrated to have the ability to greatly improve the entanglement-distribution rate. Here, we demonstrate the storage of deterministic single photons emitted from a quantum dot in a polarization-maintaining solid-state quantum memory; in addition, multi-temporal-mode memory with 1, 20 and 100 narrow single-photon pulses is also demonstrated. Multi-photons are eliminated, and only one photon at most is contained in each pulse. Moreover, the solid-state properties of both sub-systems make this configuration more stable and easier to be scalable. Our work will be helpful in the construction of efficient quantum repeaters based on all-solid-state devices. PMID:26468996

  2. European Synchrotron Radiation Facility

    International Nuclear Information System (INIS)

    Buras, B.

    1985-01-01

    How a European Synchrotron Radiation Facility has developed into a detailed proposal recently accepted as the basis for construction of the facility at Grenoble is discussed. In November 1977, the General Assembly of the European Science Foundation (ESF) approved the report of the ESF working party on synchrotron radiation entitled Synchrotron Radiation - a Perspective View for Europe. This report contained as one of its principal recommendations that work should commence on a feasibility study for a European synchrotron radiation laboratory having a dedicated hard X-ray storage ring and appropriate advanced instrumentation. In order to prepare a feasibility study the European Science Foundation set up the Ad-hoc Committee on Synchrotron Radiation, which in turn formed two working groups: one for the machine and another for instrumentation. This feasibility study was completed in 1979 with the publication of the Blue Book describing in detail the so called 1979 European Synchrotron Radiation Facility. The heart of the facility was a 5 GeV electron storage ring and it was assumed that mainly the radiation from bending magnets will be used. The facility is described

  3. Metrology of reflection optics for synchrotron radiation

    International Nuclear Information System (INIS)

    Takacs, P.Z.

    1985-09-01

    Recent years have seen an almost explosive growth in the number of beam lines on new and existing synchrotron radiation facilities throughout the world. The need for optical components to utilize the unique characteristics of synchrotron radiation has increased accordingly. Unfortunately, the technology to manufacture and measure the large, smooth, exotic optical surfaces required to focus and steer the synchrotron radiation beam has not progressed as rapidly as the operational demands on these components. Most companies do not wish to become involved with a project that requires producing a single, very expensive, aspheric optic with surface roughness and figure tolerances that are beyond their capabilities to measure. This paper will review some of the experiences of the National Synchrotron Light Source in procuring grazing incidence optical components over the past several years. We will review the specification process - how it is related to the function of the optic, and how it relates to the metrology available during the manufacturing process and after delivery to the user's laboratory. We will also discuss practical aspects of our experience with new technologies, such as single point diamond turning of metal mirrors and the use of SiC as a mirror material. Recent advances in metrology instrumentation have the potential to move the measurement of surface figure and finish from the research laboratory into the optical shop, which should stimulate growth and interest in the manufacturing of optics to meet the needs of the synchrotron radiation user community

  4. Study on the plasma transport in the T-10 tokamak using deuterium single pulse feed

    International Nuclear Information System (INIS)

    Vasin, N.L.; Vershkov, V.A.; Zhuravlev, V.A.

    1984-01-01

    The experimental data and the results of simulation of a plasma density profile at low pulse feed of a working gas in two modes of the T-10 tokamak with average electron density anti n sub(e)=3.5x10 13 cm -3 , plasma current 220 kA and various values of the longitudinal magnetic field Hsub(Z). For the first mode Hsub(Z) constituted 15 koE for the second one - 30 koE. Combined consideration of electron density profile at the stationary discharge stage and profile evolution dynamics at pulse feed permitted to estimate pinch velocity of a plasma. The diffusion and pinch velocity coefficients in this method to a considerable extent are determined by their parametric dependences. The calculations during feed with the constant diffusion coefficients and pinching velocities as well as with the diffusion coefficient varying inversely proportional to n sub(e) are presented. It is shown that in the low magnetic field mode the pinch velocity values for the medium regions of a filament do not contradict neoclassical values. At the same time in the high magnetic field mode for explaining the n sub(e) growth dynamics the pinch velocity value exceeding the neoclassical value more than by the order value

  5. National Synchrotron Light Source: vacuum system for National Synchrotron Light Source

    International Nuclear Information System (INIS)

    Schuchman, J.C.; Godel, J.B.; Jordan, W.; Oversluizen, T.

    1978-01-01

    The National Synchrotron Light Source (NSLS), a 24 million dollar project under construction at Brookhaven National Laboratory (BNL), is a research facility dedicated to the production of synchrotron radiation. Synchrotron radiation is that radiation produced by the acceleration of charged particles at near the speed of light. This facility will provide a continuous spectrum of radiation from the vacuum ultraviolet to the hard x-ray range. The radiation will be highly intense, 100% polarized, extremely well collimated and will have a pulsed time structure. The radiation will be produced in two electron storage rings at energies of 700 MeV and 2.5 GeV, respectively. A maximum of one ampere at 2 GeV, or one-half ampere at 2.5 GeV, of electron beam will be stored

  6. Pulsed, Single-Frequency, 2-um Seed Source for Coherent LIDAR Applications Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The primary objective of the proposed Phase II effort is to develop and deliver a ruggedized, single-frequency, mJ-level, 2050-nm master oscillator power amplifier...

  7. From single-pulsed field gradient to double-pulsed field gradient MR: gleaning new microstructural information and developing new forms of contrast in MRI.

    Science.gov (United States)

    Shemesh, Noam; Ozarslan, Evren; Komlosh, Michal E; Basser, Peter J; Cohen, Yoram

    2010-08-01

    One of the hallmarks of diffusion NMR and MRI is its ability to utilize restricted diffusion to probe compartments much smaller than the excited volume or the MRI voxel, respectively, and to extract microstructural information from them. Single-pulsed field gradient (s-PFG) MR methodologies have been employed with great success to probe microstructures in various disciplines, ranging from chemistry to neuroscience. However, s-PFG MR also suffers from inherent shortcomings, especially when specimens are characterized by orientation or size distributions: in such cases, the microstructural information available from s-PFG experiments is limited or lost. Double-pulsed field gradient (d-PFG) MR methodology, an extension of s-PFG MR, has attracted attention owing to recent theoretical studies predicting that it can overcome certain inherent limitations of s-PFG MR. In this review, we survey the microstructural features that can be obtained from conventional s-PFG methods in the different q regimes, and highlight its limitations. The experimental aspects of d-PFG methodology are then presented, together with an overview of its theoretical underpinnings and a general framework for relating the MR signal decay and material microstructure, affording new microstructural parameters. We then discuss recent studies that have validated the theory using phantoms in which the ground truth is well known a priori, a crucial step prior to the application of d-PFG methodology in neuronal tissue. The experimental findings are in excellent agreement with the theoretical predictions and reveal, inter alia, zero-crossings of the signal decay, robustness towards size distributions and angular dependences of the signal decay from which accurate microstructural parameters, such as compartment size and even shape, can be extracted. Finally, we show some initial findings in d-PFG MR imaging. This review lays the foundation for future studies, in which accurate and novel microstructural

  8. Numerical simulations of single and double ionization of H2 in short intense laser pulses

    International Nuclear Information System (INIS)

    Baier, Silvio

    2008-01-01

    Rescattering is the dominant process leading to double ionization in atoms and molecules interacting with linearly polarized laser pulses with wavelengths around 800 nm and in an intensity regime of 10 14 to 10 15 W/cm 2 . Using numerical integrations of the two-electron Schroedinger equation of the Hydrogen molecule in appropriate reduced dimensions two mechanisms, namely correlated emission of the electrons and excitation followed by field ionization after rescattering, could be identified and characterized. With the help of a planar model in reduced dimensions these mechanisms were quantitatively compared by their dependence on the molecular alignment with respect to the polarization axis. Two additional mechanisms, which are also related to rescattering, could be identified as well. (orig.)

  9. Low loss depressed cladding waveguide inscribed in YAG:Nd single crystal by femtosecond laser pulses.

    Science.gov (United States)

    Okhrimchuk, Andrey; Mezentsev, Vladimir; Shestakov, Alexander; Bennion, Ian

    2012-02-13

    A depressed cladding waveguide with record low loss of 0.12 dB/cm is inscribed in YAG:Nd(0.3at.%) crystal by femtosecond laser pulses with an elliptical beam waist. The waveguide is formed by a set of parallel tracks which constitute the depressed cladding. It is a key element for compact and efficient CW waveguide laser operating at 1064 nm and pumped by a multimode laser diode. Special attention is paid to mechanical stress resulting from the inscription process. Numerical calculation of mode distribution and propagation loss with the elasto-optical effect taken into account leads to the conclusion that the depressed cladding is a dominating factor in waveguide mode formation, while the mechanical stress only slightly distorts waveguide modes.

  10. High-efficiency 3 W/40 K single-stage pulse tube cryocooler for space application

    Science.gov (United States)

    Zhang, Ankuo; Wu, Yinong; Liu, Shaoshuai; Liu, Biqiang; Yang, Baoyu

    2018-03-01

    Temperature is an extremely important parameter for space-borne infrared detectors. To develop a quantum-well infrared photodetector (QWIP), a high-efficiency Stirling-type pulse tube cryocooler (PTC) has been designed, manufactured and experimentally investigated for providing a large cooling power at 40 K cold temperature. Simulated and experimental studies were carried out to analyse the effects of low temperature on different energy flows and losses, and the performance of the PTC was improved by optimizing components and parameters such as regenerator and operating frequency. A no-load lowest temperature of 26.2 K could be reached at a frequency of 51 Hz, and the PTC could efficiently offer cooling power of 3 W at 40 K cold temperature when the input power was 225 W. The efficiency relative to the Carnot efficiency was approximately 8.4%.

  11. Iron-related toxicity of single-walled carbon nanotubes and crocidolite fibres in human mesothelial cells investigated by Synchrotron XRF microscopy.

    Science.gov (United States)

    Cammisuli, Francesca; Giordani, Silvia; Gianoncelli, Alessandra; Rizzardi, Clara; Radillo, Lucia; Zweyer, Marina; Da Ros, Tatiana; Salomé, Murielle; Melato, Mauro; Pascolo, Lorella

    2018-01-15

    Carbon nanotubes (CNTs) are promising products in industry and medicine, but there are several human health concerns since their fibrous structure resembles asbestos. The presence of transition metals, mainly iron, in the fibres seems also implicated in the pathogenetic mechanisms. To unravel the role of iron at mesothelial level, we compared the chemical changes induced in MeT-5A cells by the exposure to asbestos (crocidolite) or CNTs at different content of iron impurities (raw-SWCNTs, purified- and highly purified-SWCNTs). We applied synchrotron-based X-Ray Fluorescence (XRF) microscopy and soft X-ray imaging (absorption and phase contrast images) to monitor chemical and morphological changes of the exposed cells. In parallel, we performed a ferritin assay. X-ray microscopy imaging and XRF well localize the crocidolite fibres interacting with cells, as well as the damage-related morphological changes. Differently, CNTs presence could be only partially evinced by low energy XRF through carbon distribution and sometimes iron co-localisation. Compared to controls, the cells treated with raw-SWCNTs and crocidolite fibres showed a severe alteration of iron distribution and content, with concomitant stimulation of ferritin production. Interestingly, highly purified nanotubes did not altered iron metabolism. The data provide new insights for possible CNTs effects at mesothelial/pleural level in humans.

  12. Experimental Charge Density in an Oxidized Trinuclear Iron Complex using 15 K Synchrotron and 100 K Conventional Single-Crystal X-ray Diffraction

    International Nuclear Information System (INIS)

    Overgaard, J.; Larsen, F.; Timco, G.; Iversen, B.

    2009-01-01

    The experimental electron density distribution in a crystal consisting of the simplest conceivable trinuclear carboxylate-bridged iron-μ3-oxo dianion with two α-picolinium cations has been determined using both synchrotron (15 K) and conventional (100 K) X-ray diffraction data. The constituent trinuclear oxo-centered molecule consists of six 2-bridging formate groups between the iron pairs, while the axial ligand for all iron atoms is another formate group. The compound {(Fe3O(HCOO)6(HCOO)3)2-·H2O·2(α-CH3NC5H5)+}, ( 1) crystallizes in the monoclinic space group P21/m with charge assisted hydrogen bonds linking the α-picolinium cations to the trinuclear groups. The chemical bonding in the weakly asymmetric Fe3O-core of 1 has been examined through the use of the quantum theory of atoms in molecules, and in combination with experimental d-orbital populations, a significant electron sharing is observed between the Fe atoms and the central oxygen. The central oxygen exhibits clear sp2 hybridization, and the iron atoms have valence shell charge concentrations in all metal-ligand bond directions. The relative bond strengths are evaluated based upon the charge density distribution and found to be in accordance with the geometrical results. Integrated group charges follow expectations from formal chemical valences.

  13. Synchrotron radiation: earth, environmental and materials sciences applications

    International Nuclear Information System (INIS)

    Henderson, G.; Baker, D.R.

    2002-01-01

    Mineralogical Association of Canada Short Course 30 called Synchrotron Radiation: Earth, Environmental and Materials Sciences Applications was held in Saskatoon, Saskatchewan in 2002. This short course attempts to introduce to the general earth science community some of the basics of synchrotron radiation-based research. It is not intended as a review of all aspects of every synchrotron-based technique, although it does include the important literature into which knowledge of more specific areas can be gained. Instead, it covers the basics of synchrotron research at a level suitable for those interested in beginning to use synchrotron radiation in their research. Chapter 1 covers the physics of synchrotron radiation and synchrotron storage rings in general. Chapter 2 details what the Canadian Light Source is, what it will be capable of, and the types of experiments that will be able to be performed on the beamlines. Chapter 3 covers the basics of synchrotron-based diffraction studies including both powder and single crystal studies. Chapter 4 introduces the novice user to X-ray absorption spectroscopy (EXAFS/XANES) and includes details on how to correctly reduce the data. Chapter 5 outlines the capabilities of the X-ray microprobe for chemical analyses, micro-EXAFS/XANES and imaging of geological samples. Chapter 6 gives a detailed overview of synchrotron-based X-ray photoelectron spectroscopy with application to mineralogical and geochemical studies. Finally, chapter 7 introduces the types of experiments within the geological community that are commonly performed on amorphous materials

  14. Micro-pulse polarization lidar at 1.5  μm using a single superconducting nanowire single-photon detector.

    Science.gov (United States)

    Qiu, Jiawei; Xia, Haiyun; Shangguan, Mingjia; Dou, Xiankang; Li, Manyi; Wang, Chong; Shang, Xiang; Lin, Shengfu; Liu, Jianjiang

    2017-11-01

    An all-fiber, eye-safe and micro-pulse polarization lidar is demonstrated with a polarization-maintaining structure, incorporating a single superconducting nanowire single-photon detector (SNSPD) at 1.5 μm. The time-division multiplexing technique is used to achieve a calibration-free optical layout. A single piece of detector is used to detect the backscatter signals at two orthogonal states in an alternative sequence. Thus, regular calibration of the two detectors in traditional polarization lidars is avoided. The signal-to-noise ratio of the lidar is guaranteed by using an SNSPD, providing high detection efficiency and low dark count noise. The linear depolarization ratio (LDR) of the urban aerosol is observed horizontally over 48 h in Hefei [N31°50'37'', E117°15'54''], when a heavy air pollution is spreading from the north to the central east of China. Phenomena of LDR bursts are detected at a location where a building is under construction. The lidar results show good agreement with the data detected from a sun photometer, a 532 nm visibility lidar, and the weather forecast information.

  15. Simulation investigation of thermal phase transformation and residual stress in single pulse EDM of Ti-6Al-4V

    Science.gov (United States)

    Tang, Jiajing; Yang, Xiaodong

    2018-04-01

    The thermal phase transformation and residual stress are ineluctable in the electrical discharge machining (EDM) process, and they will greatly affect the working performances of the machined surface. This paper presents a simulation study on the thermal phase transformation and residual stress in single-pulse EDM of Ti-6Al-4V, which is the most popular titanium alloy in fields such as aircraft engine and some other leading industries. A multi-physics model including thermal, hydraulic, metallography and structural mechanics was developed. Based on the proposed model, the thickness and metallographic structure of the recast layer and heat affected layer (HAZ) were investigated. The distribution and characteristics of residual stress around the discharge crater were obtained. The recast layer and HAZ at the center of crater are found to be the thinnest, and their thicknesses gradually increase approaching the periphery of the crater. The recast layer undergoes a complete α‧ (martensitic) transformation, while the HAZ is mainly composed by the α  +  β  +  α‧ three-phase microstructure. Along the depth direction of crater, the Von Mises stress increases first and then decreases, reaching its maximal value near the interface of recast layer and HAZ. In the recast layer, both compressive stress component and tensile stress component are observed. ANOVA results showed that the influence of discharge current on maximal tensile stress is more significant than that of pulse duration, while the pulse duration has more significant influence on average thickness of the recast layer and the depth location of the maximal tensile stress. The works conducted in this study will help to evaluate the quality and integrity of EDMed surface, especially when the non-destructive testing is difficult to achieve.

  16. A novel single pulsed electromagnetic field stimulates osteogenesis of bone marrow mesenchymal stem cells and bone repair.

    Science.gov (United States)

    Fu, Yin-Chih; Lin, Chih-Chun; Chang, Je-Ken; Chen, Chung-Hwan; Tai, I-Chun; Wang, Gwo-Jaw; Ho, Mei-Ling

    2014-01-01

    Pulsed electromagnetic field (PEMF) has been successfully applied to accelerate fracture repair since 1979. Recent studies suggest that PEMF might be used as a nonoperative treatment for the early stages of osteonecrosis. However, PEMF treatment requires a minimum of ten hours per day for the duration of the treatment. In this study, we modified the protocol of the single-pulsed electromagnetic field (SPEMF) that only requires a 3-minute daily treatment. In the in vitro study, cell proliferation and osteogenic differentiation was evaluated in the hBMSCs. In the in vivo study, new bone formation and revascularization were evaluated in the necrotic bone graft. Results from the in vitro study showed no significant cytotoxic effects on the hBMSCs after 5 days of SPEMF treatment (1 Tesla, 30 pulses per day). hBMSC proliferation was enhanced in the SPEMF-treated groups after 2 and 4 days of treatment. The osteogenic differentiation of hBMSCs was significantly increased in the SPEMF-treated groups after 3-7 days of treatment. Mineralization also increased after 10, 15, 20, and 25 days of treatment in SPEMF-treated groups compared to the control group. The 7-day short-course treatment achieved similar effects on proliferation and osteogenesis as the 25-day treatment. Results from the in vivo study also demonstrated that both the 7-day and 25-day treatments of SPEMF increased callus formation around the necrotic bone and also increased new vessel formation and osteocyte numbers in the grafted necrotic bone at the 2nd and 4th weeks after surgery. In conclusion, the newly developed SPEMF accelerates osteogenic differentiation of cultured hBMSCs and enhances bone repair, neo-vascularization, and cell growth in necrotic bone in mice. The potential clinical advantage of the SPEMF is the short daily application and the shorter treatment course. We suggest that SPEMF may be used to treat fractures and the early stages of osteonecrosis.

  17. A novel single pulsed electromagnetic field stimulates osteogenesis of bone marrow mesenchymal stem cells and bone repair.

    Directory of Open Access Journals (Sweden)

    Yin-Chih Fu

    Full Text Available Pulsed electromagnetic field (PEMF has been successfully applied to accelerate fracture repair since 1979. Recent studies suggest that PEMF might be used as a nonoperative treatment for the early stages of osteonecrosis. However, PEMF treatment requires a minimum of ten hours per day for the duration of the treatment. In this study, we modified the protocol of the single-pulsed electromagnetic field (SPEMF that only requires a 3-minute daily treatment. In the in vitro study, cell proliferation and osteogenic differentiation was evaluated in the hBMSCs. In the in vivo study, new bone formation and revascularization were evaluated in the necrotic bone graft. Results from the in vitro study showed no significant cytotoxic effects on the hBMSCs after 5 days of SPEMF treatment (1 Tesla, 30 pulses per day. hBMSC proliferation was enhanced in the SPEMF-treated groups after 2 and 4 days of treatment. The osteogenic differentiation of hBMSCs was significantly increased in the SPEMF-treated groups after 3-7 days of treatment. Mineralization also increased after 10, 15, 20, and 25 days of treatment in SPEMF-treated groups compared to the control group. The 7-day short-course treatment achieved similar effects on proliferation and osteogenesis as the 25-day treatment. Results from the in vivo study also demonstrated that both the 7-day and 25-day treatments of SPEMF increased callus formation around the necrotic bone and also increased new vessel formation and osteocyte numbers in the grafted necrotic bone at the 2nd and 4th weeks after surgery. In conclusion, the newly developed SPEMF accelerates osteogenic differentiation of cultured hBMSCs and enhances bone repair, neo-vascularization, and cell growth in necrotic bone in mice. The potential clinical advantage of the SPEMF is the short daily application and the shorter treatment course. We suggest that SPEMF may be used to treat fractures and the early stages of osteonecrosis.

  18. LASER APPLICATIONS AND OTHER TOPICS IN QUANTUM ELECTRONICS: Dynamics of splashing of molten metals during irradiation with single CO2 laser pulses

    Science.gov (United States)

    Arutyunyan, R. V.; Baranov, V. Yu; Bol'shov, Leonid A.; Dolgov, V. A.; Malyuta, D. D.; Mezhevov, V. S.; Semak, V. V.

    1988-03-01

    An experimental investigation was made of the dynamics of the loss of the melt as a result of interaction with single-mode CO2 laser radiation pulses of 5-35 μs duration. The dynamics of splashing of the melt during irradiation with short pulses characterized by a Gaussian intensity distribution differed from that predicted by models in which the distribution of the vapor pressure was assumed to be radially homogeneous.

  19. Future Synchrotron Radiation Sources

    CERN Document Server

    Winick, Herman

    2003-01-01

    Sources of synchrotron radiation (also called synchrotron light) and their associated research facilities have experienced a spectacular growth in number, performance, and breadth of application in the past two to three decades. In 1978 there were eleven electron storage rings used as light sources. Three of these were small rings, all below 500 mega-electron volts (MeV), dedicated to this purpose; the others, with energy up to 5 giga-electron volts (GeV), were used parasitically during the operation of the ring for high energy physics research. In addition, at that time synchrotron radiation from nine cyclic electron synchrotrons, with energy up to 5 GeV, was also used parasitically. At present no cyclic synchrotrons are used, while about 50 electron storage rings are in operation around the world as fully dedicated light sources for basic and applied research in a wide variety of fields. Among these fields are structural molecular biology, molecular environmental science, materials, analytic chemistry, micr...

  20. Australian synchrotron radiation science

    International Nuclear Information System (INIS)

    White, J.W.

    1996-01-01

    Full text: The Australian Synchrotron Radiation Program, ASRP, has been set up as a major national research facility to provide facilities for scientists and technologists in physics, chemistry, biology and materials science who need access to synchrotron radiation. Australia has a strong tradition in crystallography and structure determination covering small molecule crystallography, biological and protein crystallography, diffraction science and materials science and several strong groups are working in x-ray optics, soft x-ray and vacuum ultra-violet physics. A number of groups whose primary interest is in the structure and dynamics of surfaces, catalysts, polymer and surfactant science and colloid science are hoping to use scattering methods and, if experience in Europe, Japan and USA can be taken as a guide, many of these groups will need third generation synchrotron access. To provide for this growing community, the Australian National Beamline at the Photon Factory, Tsukuba, Japan, has been established since 1990 through a generous collaboration with Japanese colleagues, the beamline equipment being largely produced in Australia. This will be supplemented in 1997 with access to the world's most powerful synchrotron x-ray source at the Advanced Photon Source, Argonne National Laboratory, USA. Some recent experiments in surface science using neutrons as well as x-rays from the Australian National Beamline will be used to illustrate one of the challenges that synchrotron x-rays may meet

  1. Tabletop synchrotron and its unique features

    International Nuclear Information System (INIS)

    Yamada, Hironari

    2002-01-01

    Two synchrotrons, AURORA and MIRRORCLE, were built in Ritsumeikan University. MIRRORCLE-20 is the smallest normal conduction synchrotron (15 cm orbit radius and 1.2 m outer diameter) in the world. It uses 2/3 resonance method for electron beam incidence but is not optimized for X-ray generation. MIRRORCLE-6 shall be optimized for X-ray generation. X-ray generated by MIRRORCLE shows very flat white light, rich in hard X-ray, pulse with width changeable from a few μs to a few ms , wide radiation angle of 25 mrad at MIRRORCLE-20 and 80 mrad at MIRRORCLE-8 and high coherence. The feature such as pulsed light and high coherence is expected to new application which photon radiation cannot practice. Imaging experiments by MIRRORCLE were carried out by Cu plate, Al plate, Teflon and acryl plate. We took a photograph of insect, electric lamp, connector, and cyclotron. New X-ray generation mechanism, X-ray strength, development of tabletop synchrotron and features of X-ray beam are explained. (S.Y.)

  2. Ultrafast molecular dynamics illuminated with synchrotron radiation

    International Nuclear Information System (INIS)

    Bozek, John D.; Miron, Catalin

    2015-01-01

    Highlights: • Ultrafast molecular dynamics probed with synchrotron radiation. • Core-excitation as probe of ultrafast dynamics through core-hole lifetime. • Review of experimental and theoretical methods in ultrafast dynamics using core-level excitation. - Abstract: Synchrotron radiation is a powerful tool for studying molecular dynamics in small molecules in spite of the absence of natural matching between the X-ray pulse duration and the time scale of nuclear motion. Promoting core level electrons to unoccupied molecular orbitals simultaneously initiates two ultrafast processes, nuclear dynamics on the potential energy surfaces of the highly excited neutral intermediate state of the molecule on the one hand and an ultrafast electronic decay of the intermediate excited state to a cationic final state, characterized by a core hole lifetime. The similar time scales of these processes enable core excited pump-probe-type experiments to be performed with long duration X-ray pulses from a synchrotron source. Recent results obtained at the PLIEADES beamline concerning ultrafast dissociation of core excited states and molecular potential energy curve mapping facilitated by changes in the geometry of the short-lived intermediate core excited state are reviewed. High brightness X-ray beams combined with state-of-the art electron and ion-electron coincidence spectrometers and highly sophisticated theoretical methods are required to conduct these experiments and to achieve a full understanding of the experimental results.

  3. Tabletop synchrotron and its unique features

    CERN Document Server

    Yamada, H

    2002-01-01

    Two synchrotrons, AURORA and MIRRORCLE, were built in Ritsumeikan University. MIRRORCLE-20 is the smallest normal conduction synchrotron (15 cm orbit radius and 1.2 m outer diameter) in the world. It uses 2/3 resonance method for electron beam incidence but is not optimized for X-ray generation. MIRRORCLE-6 shall be optimized for X-ray generation. X-ray generated by MIRRORCLE shows very flat white light, rich in hard X-ray, pulse with width changeable from a few mu s to a few ms , wide radiation angle of 25 mrad at MIRRORCLE-20 and 80 mrad at MIRRORCLE-8 and high coherence. The feature such as pulsed light and high coherence is expected to new application which photon radiation cannot practice. Imaging experiments by MIRRORCLE were carried out by Cu plate, Al plate, Teflon and acryl plate. We took a photograph of insect, electric lamp, connector, and cyclotron. New X-ray generation mechanism, X-ray strength, development of tabletop synchrotron and features of X-ray beam are explained. (S.Y.)

  4. Single shot damage mechanism of Mo/Si multilayer optics under intense pulsed XUV-exposures

    NARCIS (Netherlands)

    Khorsand, A.R.; Sobierajski, R.; Louis, Eric; Bruijn, S.; Gleeson, A.; van de Kruijs, Robbert Wilhelmus Elisabeth; Gullikson, E.M.; Bijkerk, Frederik

    2010-01-01

    We investigated single shot damage of Mo/Si multilayer coatings exposed to the intense fs XUV radiation at the Free-electron LASer facility in Hamburg - FLASH. The interaction process was studied in situ by XUV reflectometry, time resolved optical microscopy, and “post-mortem” by

  5. Single-session combination treatment with intense pulsed light and nonablative fractional photothermolysis: a split-face study.

    Science.gov (United States)

    Kearney, Chris; Brew, Daniel

    2012-07-01

    Intense pulsed light (IPL) and fractional photothermolysis (FP) are effective nonablative treatments for photoaging. To investigate the safety and efficacy of administering these two treatments in the same session with the aim of maximizing results while maintaining safety and minimizing downtime. We sought to compare the efficacy of the combination treatment with that of individual treatments of IPL and FP by conducting a split-face study. Twenty-nine subjects received a full-face standard-strength treatment with IPL immediately followed by treatment with 1550-nm FP. A further 14 patients underwent a split-face study comparing combined IPL and FP on one side of the face with these two treatments performed in isolation, 4 weeks apart, on the other side. The combination treatment achieved results statistically superior to treatment with IPL alone, FP alone, and treatment with IPL and FP performed 4 weeks apart. Downtime and adverse events were similar to those expected with individual treatments of IPL or FP alone. Intense pulsed light and PF appear to be synergistic when performed together in a single session, and the combination treatment is associated with a good safety profile and minimal downtime. © 2012 by the American Society for Dermatologic Surgery, Inc. Published by Wiley Periodicals, Inc.

  6. Beam extraction control systems of the fast-cycling synchrotron

    International Nuclear Information System (INIS)

    Toumanian, A.; Zapolski, N.; Nickogosian, V.; Ananian, A.; Kazarian, A.; Khoetsian, M.; Agababian, A.; Matevosian, A.

    1992-01-01

    A compact system controlling the extraction of different beams (gamma, electron, synchrotron radiation) in single and simultaneous operation modes at high electromagnetic disturbances level based on using one computer of IBM PC/AT type is described. (author)

  7. ANALYTICAL EXPRESSION FOR THE ELECTRIC FIELD OF THE SINGLE MODE LASER HOMOGENEOUS BROADENING IN THE PULSE REGIME

    Directory of Open Access Journals (Sweden)

    S. Ayadi

    2015-07-01

    Full Text Available The simplest model of the laser is that of a single mode system homogenously broadened. The dynamical behavior of this laser is described by three differential equations, called Haken-Lorenz equations[1],  similar to the Lorenz model [1] already known to predict deterministic chaos. In previous recent work [5-7] we have proposed a simple harmonic expansion method to obtain a series of harmonics terms that yield analytical solutions to the laser equations. ¶This method allows us to derive an analytical expression of the laser field amplitude  when this last  undergoes a  periodic oscillations around zero mean value. We also obtain an analytical expression of the pulsing frequency.

  8. Optoelectronic Picosecond Detection of Synchrotron X-rays

    Energy Technology Data Exchange (ETDEWEB)

    Durbin, Stephen M. [Purdue Univ., West Lafayette, IN (United States)

    2017-08-04

    The goal of this research program was to develop a detector that would measure x-ray time profiles with picosecond resolution. This was specifically aimed for use at x-ray synchrotrons, where x-ray pulse profiles have Gaussian time spreads of 50-100 ps (FWHM), so the successful development of such a detector with picosecond resolution would permit x-ray synchrotron studies to break through the pulse width barrier. That is, synchrotron time-resolved studies are currently limited to pump-probe studies that cannot reveal dynamics faster than ~50 ps, whereas the proposed detector would push this into the physically important 1 ps domain. The results of this research effort, described in detail below, are twofold: 1) the original plan to rely on converting electronic signals from a semiconductor sensor into an optical signal proved to be insufficient for generating signals with the necessary time resolution and sensitivity to be widely applicable; and 2) an all-optical method was discovered whereby the x-rays are directly absorbed in an optoelectronic material, lithium tantalate, which can then be probed by laser pulses with the desired picosecond sensitivity for detection of synchrotron x-rays. This research program has also produced new fundamental understanding of the interaction of x-rays and optical lasers in materials that has now created a viable path for true picosecond detection of synchrotron x-rays.

  9. Characterization of temporal coherence of hard X-ray free-electron laser pulses with single-shot interferograms

    Directory of Open Access Journals (Sweden)

    Taito Osaka

    2017-11-01

    Full Text Available Temporal coherence is one of the most fundamental characteristics of light, connecting to spectral information through the Fourier transform relationship between time and frequency. Interferometers with a variable path-length difference (PLD between the two branches have widely been employed to characterize temporal coherence properties for broad spectral regimes. Hard X-ray interferometers reported previously, however, have strict limitations in their operational photon energies, due to the specific optical layouts utilized to satisfy the stringent requirement for extreme stability of the PLD at sub-ångström scales. The work presented here characterizes the temporal coherence of hard X-ray free-electron laser (XFEL pulses by capturing single-shot interferograms. Since the stability requirement is drastically relieved with this approach, it was possible to build a versatile hard X-ray interferometer composed of six separate optical elements to cover a wide photon energy range from 6.5 to 11.5 keV while providing a large variable delay time of up to 47 ps at 10 keV. A high visibility of up to 0.55 was observed at a photon energy of 10 keV. The visibility measurement as a function of time delay reveals a mean coherence time of 5.9 ± 0.7 fs, which agrees with that expected from the single-shot spectral information. This is the first result of characterizing the temporal coherence of XFEL pulses in the hard X-ray regime and is an important milestone towards ultra-high energy resolutions at micro-electronvolt levels in time-domain X-ray spectroscopy, which will open up new opportunities for revealing dynamic properties in diverse systems on timescales from femtoseconds to nanoseconds, associated with fluctuations from ångström to nanometre spatial scales.

  10. Design of kicker magnet and power supply unit for synchrotron beam injection

    International Nuclear Information System (INIS)

    Wang, Ju.

    1991-03-01

    To inject beams from the positron accumulator ring (PAR) into the synchrotron, a pulsed kicker magnet is used. The specifications of this kicker magnet and the power supply unit are listed and discussed in this report

  11. Pulsed IR Heating Studies of Single-Molecule DNA Duplex Dissociation Kinetics and Thermodynamics

    Science.gov (United States)

    Holmstrom, Erik D.; Dupuis, Nicholas F.; Nesbitt, David J.

    2014-01-01

    Single-molecule fluorescence spectroscopy is a powerful technique that makes it possible to observe the conformational dynamics associated with biomolecular processes. The addition of precise temperature control to these experiments can yield valuable thermodynamic information about equilibrium and kinetic rate constants. To accomplish this, we have developed a microscopy technique based on infrared laser overtone/combination band absorption to heat small (≈10−11 liter) volumes of water. Detailed experimental characterization of this technique reveals three major advantages over conventional stage heating methods: 1), a larger range of steady-state temperatures (20–100°C); 2), substantially superior spatial (≤20 μm) control; and 3), substantially superior temporal (≈1 ms) control. The flexibility and breadth of this spatial and temporally resolved laser-heating approach is demonstrated in single-molecule fluorescence assays designed to probe the dissociation of a 21 bp DNA duplex. These studies are used to support a kinetic model based on nucleic acid end fraying that describes dissociation for both short (10 bp) DNA duplexes. These measurements have been extended to explore temperature-dependent kinetics for the 21 bp construct, which permit determination of single-molecule activation enthalpies and entropies for DNA duplex dissociation. PMID:24411254

  12. Synchrotron radiation sources: general features and vacuum system

    International Nuclear Information System (INIS)

    Craievich, A.F.

    1985-01-01

    In the last years the electron or positron storage rings, which were until 1970 only used for high energy physics experiments, begun to be built in several countries exclusively as electromagnetic radiation source (synchrotron radiation). The sources are generally made up by injector (linear accelerator or microtron), 'booster' (synchrotron), storage ring, insertions ('Wigglers' and ondulators) and light lines. The interest by these sources are due to the high intensity, large spectrum (from infrared to the X-rays), polarization and pulsed structure of the produced radiation. For the ultra-vacuum obtainement, necessary for the functioning storage rings (p=10 -9 Torr), several special procedures are used. In Brazil the Synchrotron Radiation National Laboratory of the CNPq worked out a conceptual project of synchrotron radiation source, whose execution should begin by the construction of the several components prototypes. (L.C.) [pt

  13. Properties of synchrotron radiation

    International Nuclear Information System (INIS)

    Materlik, G.

    1982-01-01

    This paper forms the introductory chapter to a book concerning the use of synchrotron radiation for investigation of the structure and mechanism of biological macromolecules. After a historical section, the physics of synchrotron radiation is summarized so that the most promising experiments may be extrapolated. Irradiated power and intensity, polarization and angular distribution, brilliance of a real source, and developments such as wigglers and undulators are briefly dealt with. The paper includes a tabulated compilation of proposed and operating machines in 1982, with some of their characteristics. (U.K.)

  14. Compact synchrotron light sources

    CERN Document Server

    Weihreter, Ernst

    1996-01-01

    This book covers a new niche in circular accelerator design, motivated by the promising industrial prospects of recent micromanufacturing methods - X-ray lithography, synchrotron radiation-based micromachining and microanalysis techniques. It describes the basic concepts and the essential challenges for the development of compact synchrotron radiation sources from an accelerator designer's point of view and gives an outline of the actual state of the art. The volume is intended as an introduction and as a reference for physicists, engineers and managers involved in this rapidly developing fiel

  15. Differential pulse amplitude modulation for multiple-input single-output OWVLC

    Science.gov (United States)

    Yang, S. H.; Kwon, D. H.; Kim, S. J.; Son, Y. H.; Han, S. K.

    2015-01-01

    White light-emitting diodes (LEDs) are widely used for lighting due to their energy efficiency, eco-friendly, and small size than previously light sources such as incandescent, fluorescent bulbs and so on. Optical wireless visible light communication (OWVLC) based on LED merges lighting and communications in applications such as indoor lighting, traffic signals, vehicles, and underwater communications because LED can be easily modulated. However, physical bandwidth of LED is limited about several MHz by slow time constant of the phosphor and characteristics of device. Therefore, using the simplest modulation format which is non-return-zero on-off-keying (NRZ-OOK), the data rate reaches only to dozens Mbit/s. Thus, to improve the transmission capacity, optical filtering and pre-, post-equalizer are adapted. Also, high-speed wireless connectivity is implemented using spectrally efficient modulation methods: orthogonal frequency division multiplexing (OFDM) or discrete multi-tone (DMT). However, these modulation methods need additional digital signal processing such as FFT and IFFT, thus complexity of transmitter and receiver is increasing. To reduce the complexity of transmitter and receiver, we proposed a novel modulation scheme which is named differential pulse amplitude modulation. The proposed modulation scheme transmits different NRZ-OOK signals with same amplitude and unit time delay using each LED chip, respectively. The `N' parallel signals from LEDs are overlapped and directly detected at optical receiver. Received signal is demodulated by power difference between unit time slots. The proposed scheme can overcome the bandwidth limitation of LEDs and data rate can be improved according to number of LEDs without complex digital signal processing.

  16. Pulsed neutron sources at KAON

    International Nuclear Information System (INIS)

    Thorson, I.M.; Egelstaff, P.A.; Craddock, M.K.

    1991-01-01

    The proposed KAON Factory facility at TRIUMF consists of a number of synchrotrons and storage rings which offer proton beams of energies between 0.45 and 30 GeV with varying pulse amplitudes, widths and repetition rates. Various possibilities for feeding these beams to a pulsed neutron facility and their potential for future development are examined. The incremental cost of such a pulsed neutron facility is estimated approximately. (author)

  17. Relativistic electron beams driven by single-cycle laser pulses at kHz repetition rate (Conference Presentation)

    Science.gov (United States)

    Faure, Jérôme; Guénot, Diego; Gustas, Dominykas; Vernier, Aline; Beaurepaire, Benoît; Böhle, Frederik; López-Martens, Rodrigo; Lifschitz, Agustin

    2017-05-01

    Laser-plasma accelerators are usually driven by 100-TW class laser systems with rather low repetition rates. However, recent years have seen the emergence of laser-plasma accelerators operating with kHz lasers and energies lower than 10 mJ. The high repetition-rate is particularly interesting for applications requiring high stability and high signal-to-noise ratio but lower energy electrons. For example, our group recently demonstrated that kHz laser-driven electron beams could be used to capture ultrafast structural dynamics in Silicon nano-membranes via electron diffraction with picosecond resolution. In these first experiments, electrons were injected in the density gradients located at the plasma exit, resulting in rather low energies in the 100 keV range. The electrons being nonrelativistic, the bunch duration quickly becomes picosecond long. Relativistic energies are required to mitigate space charge effects and maintain femtosecond bunches. In this paper, we will show very recent results where electrons are accelerated in laser-driven wakefields to relativistic energies, reaching up to 5 MeV at kHz repetition rate. The electron energy was increased by nearly two orders of magnitude by using single-cycle laser pulses of 3.5 fs, with only 2.5 mJ of energy. Using such short pulses of light allowed us to resonantly excite high amplitude and nonlinear plasma waves at high plasma density, ne=1.5-2×1020 cm-3, in a regime close to the blow-out regime. Electrons had a peaked distribution around 5 MeV, with a relative energy spread of 30 %. Charges in the 100's fC/shot and up to pC/shot where measured depending on plasma density. The electron beam was fairly collimated, 20 mrad divergence at Full Width Half Maximum. The results show remarkable stability of the beam parameters in terms of beam pointing and electron distribution. 3D PIC simulations reproduce the results very well and indicate that electrons are injected by the ionization of Nitrogen atoms, N5+ to N6

  18. Solid-state reactivity explored in situ by synchrotron radiation on single crystals: from SrFeO2.5 to SrFeO3 via electrochemical oxygen intercalation

    International Nuclear Information System (INIS)

    Maity, A; Dutta, R; Penkala, B; Ceretti, M; Letrouit-Lebranchu, A; Perichon, A; Paulus, W; Chernyshov, D; Piovano, A; Bossak, A; Meven, M

    2015-01-01

    In this study we demonstrate the feasibility of following up a chemical reaction by single crystal x-ray (synchrotron) diffraction under operando conditions, carried out in a specially designed electrochemical cell mounted on the BM01A at the European Synchrotron Radiation Facility (ESRF). We investigated in detail the electrochemical oxidation of SrFeO 2.5 to SrFeO 3 on a spherical single crystal of 70 µm diameter by in situ diffraction at an ambient temperature. Complete data sets were obtained by scanning the whole reciprocal space using a 2M Pilatus detector, resulting in 3600 frames with a resolution of 0.1° per data set, each obtained in 18 min. The crystal was mounted in a specially designed electrochemical cell with 1N KOH used as the electrolyte. During the electrochemical oxidation, the reaction proceeds following the phase sequence SrFeO 2.5 /SrFeO 2.75 /SrFeO 2.875 /SrFeO 3 , structurally accompanied by establishing a complex series of long-range oxygen vacancy ordering, which gets instantly organized at ambient temperature. The topotactic reaction pathway is discussed in terms of the evolution of the twin domain structure. The formation of SrFeO 2.875 is accompanied by the formation of diffuse streaks along the [1 0 0]-direction of the perovskite cell, reaching high d-spacings. The diffuse streaks are discussed and are thought to originate from a modified twin structure induced by the SrFeO 2.75 to SrFeO 2.875 transition, and the associated changes in the domain structure, developed during the oxygen intercalation. We equally analysed and discussed in detail the twin structure of all the title compounds. We confirm the ground state of SrFeO 2.5 is able to adopt the Imma space group symmetry, showing stacking faults of the tetrahedral layers along the stacking axis of the brownmillerite unit cell, indicated by the 1D diffuse rods. We showed that in situ single crystal diffraction has huge potential in the study of non-stoichiometric compounds

  19. Solid-state reactivity explored in situ by synchrotron radiation on single crystals: from SrFeO2.5 to SrFeO3 via electrochemical oxygen intercalation

    Science.gov (United States)

    Maity, A.; Dutta, R.; Penkala, B.; Ceretti, M.; Letrouit-Lebranchu, A.; Chernyshov, D.; Perichon, A.; Piovano, A.; Bossak, A.; Meven, M.; Paulus, W.

    2015-12-01

    In this study we demonstrate the feasibility of following up a chemical reaction by single crystal x-ray (synchrotron) diffraction under operando conditions, carried out in a specially designed electrochemical cell mounted on the BM01A at the European Synchrotron Radiation Facility (ESRF). We investigated in detail the electrochemical oxidation of SrFeO2.5 to SrFeO3 on a spherical single crystal of 70 µm diameter by in situ diffraction at an ambient temperature. Complete data sets were obtained by scanning the whole reciprocal space using a 2M Pilatus detector, resulting in 3600 frames with a resolution of 0.1° per data set, each obtained in 18 min. The crystal was mounted in a specially designed electrochemical cell with 1N KOH used as the electrolyte. During the electrochemical oxidation, the reaction proceeds following the phase sequence SrFeO2.5/SrFeO2.75/SrFeO2.875/SrFeO3, structurally accompanied by establishing a complex series of long-range oxygen vacancy ordering, which gets instantly organized at ambient temperature. The topotactic reaction pathway is discussed in terms of the evolution of the twin domain structure. The formation of SrFeO2.875 is accompanied by the formation of diffuse streaks along the [1 0 0]-direction of the perovskite cell, reaching high d-spacings. The diffuse streaks are discussed and are thought to originate from a modified twin structure induced by the SrFeO2.75 to SrFeO2.875 transition, and the associated changes in the domain structure, developed during the oxygen intercalation. We equally analysed and discussed in detail the twin structure of all the title compounds. We confirm the ground state of SrFeO2.5 is able to adopt the Imma space group symmetry, showing stacking faults of the tetrahedral layers along the stacking axis of the brownmillerite unit cell, indicated by the 1D diffuse rods. We showed that in situ single crystal diffraction has huge potential in the study of non-stoichiometric compounds under operando

  20. Reflectometry with synchrotron radiation

    International Nuclear Information System (INIS)

    Krumrey, Michael; Cibik, Levent; Fischer, Andreas; Gottwald, Alexander; Kroth, Udo; Scholze, Frank

    2014-01-01

    The measurement of the reflectivity for VUV, XUV, and X-radiation at the PTB synchrotron radiation sources is described. The corresponding data of the used beams are presented. Results of experiments on a Cu-Ni double-layer, SiO 2 , Si, and MgF 2 are presented. (HSI)

  1. The World of Synchrotrons

    Indian Academy of Sciences (India)

    Charged-particles when accelerated radiateelectromag- netic energy. This interesting physical phenomenon, now known by the name synchrotron radiation had its theoretical beginnings, a long time ago, at the time of classical electrodynamics. These theoretical studies had to wait for about half a century till the ...

  2. The World of Synchrotrons

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 6; Issue 11. The World of Synchrotrons. Sameen Ahmed Khan. General Article Volume 6 Issue 11 November 2001 pp 77-84. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/006/11/0077-0084 ...

  3. Characteristics of synchrotron radiation

    International Nuclear Information System (INIS)

    Brown, G.S.

    1984-01-01

    The characteristics and production of synchrotron radiation are qualitatively discussed. The spectral properties of wigglers and undulators are briefly described. Possible applications in condensed matter physics are outlined. These include atomic and molecular studies, crystallography, impurities in solids and radiographic imaging

  4. Synchrotron radiation research

    International Nuclear Information System (INIS)

    Markus, N.

    1995-01-01

    In the many varied application fields of accelerators, synchrotron radiation ranks as one of the most valuable and widely useful tools. Synchrotron radiation is produced in multi-GeV electron synchrotrons and storage rings, and emerges tangentially in a narrow vertical fan. Synchrotron radiation has been used extensively for basic studies and, more recently, for applied research in the chemical, materials, biotechnology and pharmaceutical industries. Initially, the radiation was a byproduct of high energy physics laboratories but the high demand soon resulted in the construction of dedicated electron storage rings. The accelerator technology is now well developed and a large number of sources have been constructed, with energies ranging from about 1.5 to 8 GeV including the 6 GeV European Synchrotron Radiation Facility (ESRF) source at Grenoble, France. A modern third-generation synchrotron radiation source has an electron storage ring with a complex magnet lattice to produce ultra-low emittance beams, long straights for 'insertion devices', and 'undulator' or 'wiggler' magnets to generate radiation with particular properties. Large beam currents are necessary to give high radiation fluxes and long beam lifetimes require ultra high vacuum systems. Industrial synchrotron radiation research programmes use either Xray diffraction or spectroscopy to determine the structures of a wide range of materials. Biological and pharmaceutical applications study the functions of various proteins. With this knowledge, it is possible to design molecules to change protein behaviour for pharmaceuticals, or to configure more active proteins, such as enzymes, for industrial processes. Recent advances in molecular biology have resulted in a large increase in protein crystallography studies, with researchers using crystals which, although small and weakly diffracting, benefit from the high intensity. Examples with commercial significance include the study of

  5. Pulsed-laser-deposited, single-crystalline Cu2O films with low resistivity achieved through manipulating the oxygen pressure

    Science.gov (United States)

    Liu, Xiaohui; Xu, Meng; Zhang, Xijian; Wang, Weiguang; Feng, Xianjin; Song, Aimin

    2018-03-01

    Low-resistivity, single-crystalline Cu2O films were realized on MgO (110) substrates through manipulating the oxygen pressure (PO2) of pulsed-laser deposition. X-ray diffraction and high resolution transmission electron microscopy measurements revealed that the films deposited at PO2 of 0.06 and 0.09 Pa were single phase Cu2O and the 0.09-Pa-deposited film exhibited the best crystallinity with an epitaxial relationship of Cu2O (110)∥MgO (110) with Cu2O (001)∥MgO (001). The pure phase Cu2O films exhibited higher transmittances and larger band gaps with an optical band gap of 2.56 eV obtained for the 0.09 Pa-deposited film. Hall-effect measurements demonstrated that the Cu2O film deposited at 0.09 Pa had the lowest resistivity of 6.67 Ω cm and highest Hall mobility of 23.75 cm2 v-1 s-1.

  6. Effect of supply voltage and body-biasing on single-event transient pulse quenching in bulk fin field-effect-transistor process

    International Nuclear Information System (INIS)

    Yu Jun-Ting; Chen Shu-Ming; Chen Jian-Jun; Huang Peng-Cheng; Song Rui-Qiang

    2016-01-01

    Charge sharing is becoming an important topic as the feature size scales down in fin field-effect-transistor (FinFET) technology. However, the studies of charge sharing induced single-event transient (SET) pulse quenching with bulk FinFET are reported seldomly. Using three-dimensional technology computer aided design (3DTCAD) mixed-mode simulations, the effects of supply voltage and body-biasing on SET pulse quenching are investigated for the first time in bulk FinFET process. Research results indicate that due to an enhanced charge sharing effect, the propagating SET pulse width decreases with reducing supply voltage. Moreover, compared with reverse body-biasing (RBB), the circuit with forward body-biasing (FBB) is vulnerable to charge sharing and can effectively mitigate the propagating SET pulse width up to 53% at least. This can provide guidance for radiation-hardened bulk FinFET technology especially in low power and high performance applications. (paper)

  7. Measurement of the ratio of double-to-single photoionization of helium at 2.8 keV using synchrotron radiation

    International Nuclear Information System (INIS)

    Levin, J.C.; Lindle, D.W.; Keller, N.; Miller, R.D.; Azuma, Y.; Mansour, N.B.; Berry, H.G.; Sellin, I.A.

    1991-01-01

    We report the first measurement of the ratio of double-to-single photoionization of helium well above the double-ionization threshold. Using a time-of-flight technique, we find He ++ /He + =1.6±0.3% at hν=2.8 keV. This value lies between calculations by Amusia (2.3%) and by Samson, who predicts 1.2% by analogy with electron-impact ionization cross sections of singly charged ions. Good agreement is obtained with older shake calculations of Byron and Joachain, and of Aberg, who predict 1.7%

  8. Modeling of time evolution of power and temperature in single-pulse and multi-pulses diode-pumped alkali vapor lasers.

    Science.gov (United States)

    Shen, Binglin; Huang, Jinghua; Xu, Xingqi; Xia, Chunsheng; Pan, Bailiang

    2017-06-12

    A physical model combining rate, power propagation, and transient heat conduction equations for diode-pumped alkali vapor lasers (DPAL) is applied to a pulsed Rb-CH 4 DPAL, which agrees well with the time evolution of laser power and temperature measured by K absorption spectroscopy. The output feature and temperature rise of a multi-pulse DPAL are also calculated in the time domain, showing that if we energize the pump light when the temperature rise decays to 1/2, rather than 1/e of its maximum, we can increase the duty cycle and obtain more output energy. The repetition rate of >100Hz is high enough to achieve QCW (quasi-continuous-wave) laser pulses.

  9. Laser synchrotron radiation and beam cooling

    Energy Technology Data Exchange (ETDEWEB)

    Esarey, E.; Sprangle, P.; Ting, A. [Naval Research Lab., Washington, DC (United States)] [and others

    1995-12-31

    The interaction of intense {approx_gt} 10{sup 18} W/cm{sup 2}, short pulse ({approx_lt} 1 ps) lasers with electron beams and plasmas can lead to the generation of harmonic radiation by several mechanisms. Laser synchrotron radiation may provide a practical method for generating tunable, near monochromatic, well collimated, short pulse x-rays in compact, relatively inexpensive source. The mechanism for the generation of laser synchrotron radiation is nonlinear Thomson scattering. Short wavelengths can be generated via Thomson scattering by two methods, (i) backscattering from relativistic electron beams, in which the radiation frequency is upshifted by the relativistic factor 4{gamma}{sup 2}, and (ii) harmonic scattering, in which a multitude of harmonics are generated with harmonic numbers extending out to the critical harmonic number nc{approx_equal}a{sub 0}{sup 3} {much_gt} 1, where a{sub 0} {approx_equal}10{sup -9}{lambda}I{sup 1/2}, {lambda} is the laser wavelength in {mu}m and I is the laser intensity in W/cm{sup 2}. Laser synchrotron sources are capable of generating short ({approx_lt} ps) x-ray pulses with high peak flux ({approx_gt} 10{sup 21} photons/s) and brightness ({approx_gt}{sup 19} photons/s-mm{sup 2}-mrad{sup 2} 0.1%BW. As the electron beam radiates via Thomson scattering, it can subsequently be cooled, i.e., the beam emittance and energy spread can be reduced. This cooling can occur on rapid ({approximately} ps) time scales. In addition, electron distributions with sufficiently small axial energy spreads can be used to generate coherent XUV radiation via a laser-pumped FEL mechanism.

  10. A spin echo sequence with a single-sided bipolar diffusion gradient pulse to obtain snapshot diffusion weighted images in moving media

    Science.gov (United States)

    Freidlin, R. Z.; Kakareka, J. W.; Pohida, T. J.; Komlosh, M. E.; Basser, P. J.

    2012-08-01

    In vivo MRI data can be corrupted by motion. Motion artifacts are particularly troublesome in Diffusion Weighted MRI (DWI), since the MR signal attenuation due to Brownian motion can be much less than the signal loss due to dephasing from other types of complex tissue motion, which can significantly degrade the estimation of self-diffusion coefficients, diffusion tensors, etc. This paper describes a snapshot DWI sequence, which utilizes a novel single-sided bipolar diffusion sensitizing gradient pulse within a spin echo sequence. The proposed method shortens the diffusion time by applying a single refocused bipolar diffusion gradient on one side of a refocusing RF pulse, instead of a set of diffusion sensitizing gradients, separated by a refocusing RF pulse, while reducing the impact of magnetic field inhomogeneity by using a spin echo sequence. A novel MRI phantom that can exhibit a range of complex motions was designed to demonstrate the robustness of the proposed DWI sequence.

  11. Single pulse two-photon fluorescence lifetime imaging (SP-FLIM) with MHz pixel rate and an all fiber based setup

    Science.gov (United States)

    Eibl, Matthias; Karpf, Sebastian; Hakert, Hubertus; Weng, Daniel; Pfeiffer, Tom; Kolb, Jan Philip; Huber, Robert

    2017-07-01

    Newly developed microscopy methods have the goal to give researches in bio-molecular science a better understanding of processes ongoing on a cellular level. Especially two-photon excited fluorescence (TPEF) microscopy is a readily applied and widespread modality. Compared to one photon fluorescence imaging, it is possible to image not only the surface but also deeper lying structures. Together with fluorescence lifetime imaging (FLIM), which provides information on the chemical composition of a specimen, deeper insights on a molecular level can be gained. However, the need for elaborate light sources for TPEF and speed limitations for FLIM hinder an even wider application. In this contribution, we present a way to overcome this limitations by combining a robust and inexpensive fiber laser for nonlinear excitation with a fast analog digitization method for rapid FLIM imaging. The applied sub nanosecond pulsed laser source is perfectly suited for fiber delivery as typically limiting non-linear effects like self-phase or cross-phase modulation (SPM, XPM) are negligible. Furthermore, compared to the typically applied femtosecond pulses, our longer pulses produce much more fluorescence photons per single shot. In this paper, we show that this higher number of fluorescence photons per pulse combined with a high analog bandwidth detection makes it possible to not only use a single pulse per pixel for TPEF imaging but also to resolve the exponential time decay for FLIM. To evaluate our system, we acquired FLIM images of a dye solution with single exponential behavior to assess the accuracy of our lifetime determination and also FLIM images of a plant stem at a pixel rate of 1 MHz to show the speed performance of our single pulse two-photon FLIM (SP-FLIM) system.

  12. Double Pass 595?nm pulsed dye laser at a 6 minute interval for the treatment of port-wine stains is not more effective than single pass

    NARCIS (Netherlands)

    Peters, M. A. D.; van Drooge, A. M.; Wolkerstorfer, A.; van Gemert, M. J. C.; van der Veen, J. P. W.; Bos, J. D.; Beek, J. F.

    2012-01-01

    Background Pulsed dye laser (PDL) is the first choice for treatment of port wine stains (PWS). However, outcome is highly variable and only a few patients achieve complete clearance. The objective of the study was to compare efficacy and safety of single pass PDL with double pass PDL at a 6 minute

  13. CORNELL: Synchrotron 25

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    A recent celebration marked the twenty-fifth anniversary of the Cornell Electron Synchrotron. The major milestone in the commissioning of the synchrotron was on October 11, 1967 when Helen Edwards, Boyce McDaniel, and Maury Tigner achieved a 7 GeV beam, a worldrecord energy for electron synchrotrons at that time. Like so many advances in experimental physics, this occurred early in the morning - 3 a.m.! The transition from accelerator commissioning to high energy physics operation was extremely rapid; 7 GeV operation for data collection was routine just five weeks later. Throughout its life as a source of photon and electron beams for fixed target experiments, the synchrotron maintained energy leadership for circular electron machines. Originally designed for operation at 10 GeV, eventually it consistently provided beams for experiments at energies up to 11.6 GeV. It now operates at 5 GeV, serving as the injector for the CESR electron-positron storage ring. Robert Wilson was director of the laboratory during the design and most of the construction of the machine. He left near the end of the construction to become the first director of Fermilab and was replaced by Boyce McDaniel, who guided the laboratory from the completion of the synchrotron to the construction and early operation of CESR. Wilson recalled how the laboratory had originally proposed a 3 GeV turnkey machine to be built entirely by industry and would fit in the space previously occupied by earlier Cornell accelerators. However, members of the laboratory realized that 3 GeV would not open new physics frontiers, that the construction of the accelerator was much of the fun of doing high energy physics experiments, and that a more challenging project was needed. This led to the proposal for the 10 GeV synchrotron which was built in the ''Cornell Style'' with many of the components fabricated and nearly all of the assembly done at Cornell

  14. Blue luminescence in ZnO single crystals, nanopowders, ceramic

    International Nuclear Information System (INIS)

    LGrigorjeva; Millers, D; Pankratov, V; Kalinko, A; Grabis, J; Monty, C

    2007-01-01

    The luminescence spectra and luminescence decay processes were studied in a ZnO single crystal, nanopowders and ceramic at liquid helium and room temperature under VUV synchrotron radiation as well as under pulsed laser excitation. The exciton-exciton and exciton-multiphonon processes were compared in different ZnO nanopowders (commercial powder, powders obtained by vaporization-condensation technique) and ceramic. The possibility of luminescence decay time modification by Al 3+ doping was shown

  15. Towards diffractive imaging with single pulses of FEL radiation. Dynamics within irradiatied samples and their influence on the analysis of imaging data

    International Nuclear Information System (INIS)

    Wang, Fenglin

    2010-08-01

    3D single particle coherent diffraction imaging (CDI) of bioparticles (such as proteins, macromolecules and viruses) is one of the main possible applications of the new generation of light sources: free-electron lasers (FELs), which are now available at FLASH (Hamburg, Germany) and LCLS (Stanford, U.S.A.). The extremely bright and ultrashort FEL pulses potentially enable CDI to achieve high resolution down to subnanometer length scale. However, intense FEL pulses cause serious radiation damage in bioparticles, even during single shots, which may set the resolution limits for CDI with FELs. Currently, since the signal-to-noise ratio is very low for small biological particles, direct experimental study of radiation damage in the single particle imaging is fairly difficult. Single atomic (noble gas) clusters become good objects to reveal effects of radiation damage processes on CDI with FEL radiation. This thesis studies three aspects of the radiation damage problem, which are treated in three independent chapters: (1) Molecular Dynamics simulations to quantitively describe radiation damage processes within irradiated atomic clusters during single pulses; (2) reconstruction analysis of single-shot CDI diffraction patterns of atomic clusters, which may potentially help to understand the radiation damage occurring in biological samples; and (3) testing the effects of coating water layers in CDI, which is supposed to minimize the radiation damage in irradiated bioparticles. (orig.)

  16. Towards diffractive imaging with single pulses of FEL radiation. Dynamics within irradiatied samples and their influence on the analysis of imaging data

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Fenglin

    2010-08-15

    3D single particle coherent diffraction imaging (CDI) of bioparticles (such as proteins, macromolecules and viruses) is one of the main possible applications of the new generation of light sources: free-electron lasers (FELs), which are now available at FLASH (Hamburg, Germany) and LCLS (Stanford, U.S.A.). The extremely bright and ultrashort FEL pulses potentially enable CDI to achieve high resolution down to subnanometer length scale. However, intense FEL pulses cause serious radiation damage in bioparticles, even during single shots, which may set the resolution limits for CDI with FELs. Currently, since the signal-to-noise ratio is very low for small biological particles, direct experimental study of radiation damage in the single particle imaging is fairly difficult. Single atomic (noble gas) clusters become good objects to reveal effects of radiation damage processes on CDI with FEL radiation. This thesis studies three aspects of the radiation damage problem, which are treated in three independent chapters: (1) Molecular Dynamics simulations to quantitively describe radiation damage processes within irradiated atomic clusters during single pulses; (2) reconstruction analysis of single-shot CDI diffraction patterns of atomic clusters, which may potentially help to understand the radiation damage occurring in biological samples; and (3) testing the effects of coating water layers in CDI, which is supposed to minimize the radiation damage in irradiated bioparticles. (orig.)

  17. MICROANALYSIS OF MATERIALS USING SYNCHROTRON RADIATION.

    Energy Technology Data Exchange (ETDEWEB)

    JONES,K.W.; FENG,H.

    2000-12-01

    High intensity synchrotron radiation produces photons with wavelengths that extend from the infrared to hard x rays with energies of hundreds of keV with uniquely high photon intensities that can be used to determine the composition and properties of materials using a variety of techniques. Most of these techniques represent extensions of earlier work performed with ordinary tube-type x-ray sources. The properties of the synchrotron source such as the continuous range of energy, high degree of photon polarization, pulsed beams, and photon flux many orders of magnitude higher than from x-ray tubes have made possible major advances in the possible chemical applications. We describe here ways that materials analyses can be made using the high intensity beams for measurements with small beam sizes and/or high detection sensitivity. The relevant characteristics of synchrotron x-ray sources are briefly summarized to give an idea of the x-ray parameters to be exploited. The experimental techniques considered include x-ray fluorescence, absorption, and diffraction. Examples of typical experimental apparatus used in these experiments are considered together with descriptions of actual applications.

  18. Shifts in the metabolic function of a benthic estuarine microbial community following a single pulse exposure to silver nanoparticles

    International Nuclear Information System (INIS)

    Echavarri-Bravo, Virginia; Paterson, Lynn; Aspray, Thomas J.; Porter, Joanne S.; Winson, Michael K.; Thornton, Barry; Hartl, Mark G.J.

    2015-01-01

    The increasing use of silver nanoparticles (AgNPs) as a biocidal agent and their potential accumulation in sediments may threaten non-target natural environmental bacterial communities. In this study a microcosm approach was established to investigate the effects of well characterized OECD AgNPs (NM-300) on the function of the bacterial community inhabiting marine estuarine sediments (salinity 31‰). The results showed that a single pulse of NM-300 AgNPs (1 mg L −1 ) that led to sediment concentrations below 6 mg Ag kg −1 dry weight inhibited the bacterial utilization of environmentally relevant carbon substrates. As a result, the functional diversity changed, but recovered after 120 h under the experimental conditions. This microcosm study suggests that AgNPs under environmentally relevant experimental conditions can negatively affect bacterial function and provides an insight into the understanding of the bacterial community response and resilience to AgNPs exposure, important for informing relevant regulatory measures. - Highlights: • AgNPs affected the bacterial community function in estuarine marine sediments. • AgNPs inhibited the bacterial utilization of environmentally relevant substrates. • Heterotrophic bacterial groups showed resilience to AgNPs after 120 h exposure. • AgNPs did not affect the bacterial community structure in sediments. - AgNPs inhibited the bacterial utilization of environmentally relevant substrates and caused temporary shifts in the bacterial functional diversity in marine estuarine sediments

  19. Size dependent Raman and absorption studies of single walled carbon nanotubes synthesized by pulse laser deposition at room temperature

    Science.gov (United States)

    Dixit, Saurabh; Singhal, Sonal; Vankar, V. D.; Shukla, A. K.

    2017-10-01

    In this article, size dependent correlation of acoustic states is established for radial breathing mode (RBM). Single walled carbon nanotubes (SWCNTs) are synthesized along with carbon encapsulated iron nanoparticles by pulse laser deposition at room temperature. Ferrocene is used as a catalyst for growth of SWCNTs. Various studies such as HR-TEM, X-Ray Diffraction (XRD), Raman spectroscopy and NIR-Absorption spectroscopy are utilized to confirm the presence of SWCNTs in the as-synthesized and purified samples. RBM of SWCNTs can be differentiated here from Raman modes of carbon encapsulated iron nanoparticles by comparing their line shape asymmetry as well as oscillator strength. Furthermore, a quantum confinement model is proposed for RBM. It is invoked here that RBM is manifestation of quantum confinement of acoustic phonons. Well reported analytical relation of RBM is utilized to explore the nature of phonons responsible for RBM on the basis of quantum confinement model. Diameters of SWCNTs estimated by Raman studies are found to be in reasonably good agreement with that of NIR-absorption studies.

  20. Single-cell pulsed-field gel electrophoresis to detect the early stage of DNA fragmentation in human sperm nuclei.

    Directory of Open Access Journals (Sweden)

    Satoru Kaneko

    Full Text Available Single-cell pulsed-field gel electrophoresis (SCPFGE with dual electrode pairs was developed to detect the early stage of DNA fragmentation in human sperm. The motile sperm were purified by the commonly used density-gradient centrifugation technique and subsequent swim-up. The sperm were embedded in a thin film of agarose containing bovine trypsin (20 µg/mL and were then lysed. Prior to SCPFGE, proteolysis of DNA-binding components, such as protamine and the nuclear matrix was essential to separate the long chain fibers from the fibrous and granular fragments derived from a single nucleus. The overall electrophoretic profiles elucidated the course of DNA fragmentation. A few large fibrous fragments were observed at the beginning of the process, however, as the fragmentation advanced, the long chain fibers decreased and shortened, and, conversely, the granular fragments increased until finally almost all the DNA was shredded. Although the ejaculate contained sperm with heterogeneous stages, the purified motile sperm exhibited several dozens of uniformly elongated fibers arising from the tangled DNA at the origin, whereas a part of these fibers gave rise to fibrous fragments beyond the tip of the elongated fibers, and their numbers and sizes varied among the sperm. Conventional intra-cytoplasmic sperm injection (ICSI usually depends on intra-operative light microscopic observation to select a sperm for injection. The present results revealed that sperm motility could not give full assurance of DNA integrity. SCPFGE is likely to serve an important role in the preoperative differential diagnosis to determine the competence of the sperm population provided for injection.

  1. Nanoplasma dynamics of single large xenon clusters irradiated with superintense x-ray pulses from the linac coherent light source free-electron laser.

    Science.gov (United States)

    Gorkhover, T; Adolph, M; Rupp, D; Schorb, S; Epp, S W; Erk, B; Foucar, L; Hartmann, R; Kimmel, N; Kühnel, K-U; Rolles, D; Rudek, B; Rudenko, A; Andritschke, R; Aquila, A; Bozek, J D; Coppola, N; Erke, T; Filsinger, F; Gorke, H; Graafsma, H; Gumprecht, L; Hauser, G; Herrmann, S; Hirsemann, H; Hömke, A; Holl, P; Kaiser, C; Krasniqi, F; Meyer, J-H; Matysek, M; Messerschmidt, M; Miessner, D; Nilsson, B; Pietschner, D; Potdevin, G; Reich, C; Schaller, G; Schmidt, C; Schopper, F; Schröter, C D; Schulz, J; Soltau, H; Weidenspointner, G; Schlichting, I; Strüder, L; Ullrich, J; Möller, T; Bostedt, C

    2012-06-15

    The plasma dynamics of single mesoscopic Xe particles irradiated with intense femtosecond x-ray pulses exceeding 10(16)  W/cm2 from the Linac Coherent Light Source free-electron laser are investigated. Simultaneous recording of diffraction patterns and ion spectra allows eliminating the influence of the laser focal volume intensity and particle size distribution. The data show that for clusters illuminated with intense x-ray pulses, highly charged ionization fragments in a narrow distribution are created and that the nanoplasma recombination is efficiently suppressed.

  2. Thermally-fluctuated single-flux-quantum pulse intervals reflected in input-output characteristics of a double-flux-quantum amplifier

    Science.gov (United States)

    Mizugaki, Yoshinao; Urai, Yoshiaki; Shimada, Hiroshi

    2017-07-01

    A double-flux-quantum amplifier (DFQA) is a voltage multiplier of quantum accuracy, which we have employed at the final stage of a single-flux-quantum (SFQ) digital-to-analog converter (DAC). We recently found that experimental input-output (IO) characteristics of DFQAs were always slightly different from numerical results assuming ideally-periodic SFQ pulse trains. That is, experimental IO characteristics obtained using an over-biasing method were gradually deteriorated near their maximum operation voltages. Numerical simulation including the over-biasing method at a finite temperature suggested that the difference was likely to be attributed to thermally-fluctuated intervals of input SFQ pulses.

  3. Studying Magnetohydrodynamic Turbulence with Synchrotron Polarization Dispersion

    OpenAIRE

    Zhang, Jian-Fu; Lazarian, Alex; Lee, Hyeseung; Cho, Jungyeon

    2016-01-01

    We test a new technique of studying magnetohydrodynamic (MHD) turbulence suggested by Lazarian \\& Pogosyan, using synthetic synchrotron polarization observations. This paper focuses on a one-point statistics, which is termed the polarization frequency analysis, that is characterized by the variance of polarized emission as a function of the square of wavelengths along a single line of sight. We adopt a ratio $\\eta$ of the standard deviation of the line-of-sight turbulent magnetic field to the...

  4. Extinction correction and synchrotron radiation

    International Nuclear Information System (INIS)

    Suortti, P.

    1983-01-01

    The primary extinction factor ysub(p) is defined as the ratio of the integrated reflection from a coherently diffracting domain to the integrated kinematical reflection from the same domain. When ysub(p) is larger than 0.5 it may be approximated by ysub(p)= exp[-(αdelta) 2 ], where α is about 0.5 and delta the average size of the coherent domain when measured in units of the extinction length Λ, delta = D/Λ. Transfer equations are applied to symmetrical Laue diffraction, and the reflectivity per unit length, sigma(epsilon) is solved from the measured reflecting ratio as a function of the rocking angle epsilon = theta -thetasub(B). Measurements with conventional x-ray sources are made on single crystal slabs of Be and Si using AgKβ, MoKα 1 and CuKα radiation. The primary extinction factor ysub(p)(epsilon) is solved from a point-by-point comparison of two measurements where the extinction length Λ is changed by varying the polarization and/or wavelength of the x-ray beam. The results show that primary and secondary extinction are strongly correlated, and that the customary assumption of independent size and orientation distributions of crystal mosaics is unjustified. The structure factors for Be and Si show close agreement with other recent measurements and calculations. The limitations of the method are discussed in length, particularly the effects of beam divergences and incoherence of the rays in the crystal. It is concluded that under typical experimental conditions the requirements of the theory are met. Practical limitations arising from the use of characteristic wavelengths and unpolarized radiation prohibit the use of the full potential of the method. The properties of a synchrotron radiation source are compared with a conventional x-ray source, and it is demonstrated that the experimental limitations can be removed by the use of synchrotron radiation. A diffraction experiment with synchrotron radiation is outlined, as well as generalization of the

  5. X-ray pulse preserving single-shot optical cross-correlation method for improved experimental temporal resolution

    International Nuclear Information System (INIS)

    Beye, M.; Krupin, O.; Hays, G.; Jong, S. de; Lee, S.; Coffee, R.; Holmes, M. R.; Fry, A. R.; White, W. E.; Bostedt, C.; Schlotter, W. F.; Reid, A. H.; Rupp, D.; Lee, W.-S.; Scherz, A. O.; Chuang, Y.-D.; Cryan, J. P.; Glownia, J. M.; Foehlisch, A.; Durr, H. A.

    2012-01-01

    We measured the relative arrival time between an optical pulse and a soft x-ray pulse from a free-electron laser. This femtosecond cross-correlation measurement was achieved by observing the change in optical reflectivity induced through the absorption of a fraction of the x-ray pulse. The main x-ray pulse energy remained available for an independent pump-probe experiment where the sample may be opaque to soft x-rays. The method was employed to correct the two-pulse delay data from a canonical pump-probe experiment and demonstrate 130 ± 20 fs (FWHM) temporal resolution. We further analyze possible timing jitter sources and point to future improvements.

  6. Deep tissue optical imaging of upconverting nanoparticles enabled by exploiting higher intrinsic quantum yield through use of millisecond single pulse excitation with high peak power

    DEFF Research Database (Denmark)

    Liu, Haichun; Xu, Can T.; Dumlupinar, Gökhan

    2013-01-01

    the possible thermal side-effects of the excitation light moderate. These key results facilitate means to break through the general shallow depth limit of upconverting-nanoparticle-based fluorescence techniques, necessary for a range of biomedical applications, including diffuse optical imaging, photodynamic......We have accomplished deep tissue optical imaging of upconverting nanoparticles at 800 nm, using millisecond single pulse excitation with high peak power. This is achieved by carefully choosing the pulse parameters, derived from time-resolved rate-equation analysis, which result in higher intrinsic...... quantum yield that is utilized by upconverting nanoparticles for generating this near infrared upconversion emission. The pulsed excitation approach thus promises previously unreachable imaging depths and shorter data acquisition times compared with continuous wave excitation, while simultaneously keeping...

  7. Synchrotrons for hadron therapy: Part I

    CERN Document Server

    Badano, L; Bryant, P; Crescenti, M; Holy, P; Knaus, P; Maier, A; Pullia, M; Rossi, S

    1999-01-01

    The treatment of cancer with accelerator beams has a long history with betatrons, linacs, cyclotrons and now synchrotrons being exploited for this purpose. Treatment techniques can be broadly divided into the use of spread-out beams and scanned 'pencil' beams. The Bragg-peak behaviour of hadrons makes them ideal candidates for the latter. The combination of precisely focused 'pencil' beams with controllable penetration (Bragg peak) and high, radio-biological efficiency (light ions) opens the way to treating the more awkward tumours that are radio-resistant, complex in shape and lodged against critical organs. To accelerate light ions (probably carbon) with pulse-to-pulse energy variation, a synchrotron is the natural choice. The beam scanning system is controlled via an on-line measurement of the particle flux entering the patient and, for this reason, the beam spill must be extended in time (seconds) by a slow-extraction scheme. The quality of the dose intensity profile ultimately depends on the uniformity o...

  8. Berkeley Lab's ALS generates femtosecond synchrotron radiation

    CERN Document Server

    Robinson, A L

    2000-01-01

    A team at Berkeley's Advanced Light Source has shown how a laser time-slicing technique provides a path to experiments with ultrafast time resolution. A Lawrence Berkeley National Laboratory team has succeeded in generating 300 fs pulses of synchrotron radiation at the ALS synchrotron radiation machine. The team's members come from the Materials Sciences Division (MSD), the Center for Beam Physics in the Accelerator and Fusion Research Division and the Advanced Light Source (ALS). Although this proof-of principle experiment made use of visible light on a borrowed beamline, the laser "time-slicing" technique at the heart of the demonstration will soon be applied in a new bend magnet beamline that was designed specially for the production of femtosecond pulses of X-rays to study long-range and local order in condensed matter with ultrafast time resolution. An undulator beamline based on the same technique has been proposed that will dramatically increase the flux and brightness. The use of X-rays to study the c...

  9. Synchrotrons for hadron therapy, part 1

    CERN Document Server

    Badano, L; Bryant, P J; Crescenti, M; Holy, P; Knaus, P; Maier, A T; Pullia, M; Rossi, S

    1999-01-01

    The treatment of cancer with accelerator beams has a long history with linacs, cyclotrons and now synchrotrons being exploited for this purpose. Treatment techniques can be broadly divided into the use of spread-out beams and scanned 'pencil' beams. The Bragg-peak behaviour of hadrons makes them ideal candidates for the latter. The combination of precisely focused 'pencil' beams with controllable penetration (Bragg peak) and high, radio-biological efficiency (light ions) opens the way to treating the more awkward tumours that are radio-resistant, complex in shape and lodged against critical organs. To accelerate light ions (probably carbon) with pulse-to-pulse energy variation, a synchrotron is the natural choice. The beam scanning system is controlled via an on-line measurement of the particle flux entering the patient and, for this reason, the beam spill must be extended in time (seconds) by a slow-extraction scheme. The quality of the dose intensity profile ultimately depends on the uniformity of the beam ...

  10. The effect of the shape of single, sub-ms voltage pulses on the rates of surface immobilization and hybridization of DNA

    International Nuclear Information System (INIS)

    Cabeca, R; Rodrigues, M; Chu, V; Conde, J P; Prazeres, D M F

    2009-01-01

    Electric fields generated by single square and sinusoidal voltage pulses with amplitudes below 2 V were used to assist the covalent immobilization of single-stranded, thiolated DNA probes, onto a chemically functionalized SiO 2 surface and to assist the specific hybridization of single-stranded DNA targets with immobilized complementary probes. The single-stranded immobilized DNA probes were either covalently immobilized (chemisorption) or electrostatically adsorbed (physisorption) to a chemically functionalized surface. Comparing the speed of electric field assisted immobilization and hybridization with the corresponding control reactions (without electric field), an increase of several orders of magnitude is observed, with the reaction timescaled down from 1 to 2 h to a range between 100 ns and 1 ms. The influence of the shape of the voltage pulse (square versus sinusoidal) and its duration were studied for both immobilization and hybridization reactions. The results show that pulsed electric fields are a useful tool to achieve temporal and spatial control of surface immobilization and hybridization reactions of DNA.

  11. Brain activity modification produced by a single radioelectric asymmetric brain stimulation pulse: a new tool for neuropsychiatric treatments. Preliminary fMRI study

    Directory of Open Access Journals (Sweden)

    Castagna A

    2011-10-01

    Full Text Available Salvatore Rinaldi1,2, Vania Fontani1, Alessandro Castagna1 1Department of Neuro-Psycho-Physio Pathology, Rinaldi Fontani Institute, Florence, Italy; 2Medical School of Occupational Medicine, University of Florence, Florence, Italy Purpose: Radioelectric asymmetric brain stimulation technology with its treatment protocols has shown efficacy in various psychiatric disorders. The aim of this work was to highlight the mechanisms by which these positive effects are achieved. The current study was conducted to determine whether a single 500-millisecond radioelectric asymmetric conveyor (REAC brain stimulation pulse (BSP, applied to the ear, can effect a modification of brain activity that is detectable using functional magnetic resonance imaging (fMRI. Methods: Ten healthy volunteers, six females and four males, underwent fMRI during a simple finger-tapping motor task before and after receiving a single 500-millisecond REAC-BSP. Results: The fMRI results indicate that the average variation in task-induced encephalic activation patterns is lower in subjects following the single REAC pulse. Conclusion: The current report demonstrates that a single REAC-BSP is sufficient to modulate brain activity in awake subjects, able to be measured using fMRI. These initial results open new perspectives into the understanding of the effects of weak and brief radio pulses upon brain activity, and provide the basis for further indepth studies using REAC-BSP and fMRI. Keywords: fMRI, brain stimulation, brain modulation, REAC, neuropsychiatric treatments

  12. Study of single pulsed-field magnetization of Gd-Ba-Cu-O bulk high-temperature superconductor with a split type of armature coil for rotating machinery

    International Nuclear Information System (INIS)

    Morita, E; Matsuzaki, H; Kimura, Y; Ohtani, I; Ogata, H; Izumi, M; Nonaka, Y; Murakami, M; Ida, T; Sugimoto, H; Miki, M; Kitano, M

    2006-01-01

    We employed a Gd-bulk HTS as rotating field magnet poles aiming for a smaller and lighter axial-gap-type motor. The bulk was inserted in the split-type armature pulsed copper coils and cooled down to 77 K under zero field. Employing the bulk magnet to HTS rotating machinery, the number of pulsed field magnetizations should be reduced for practical use. Thereby, a single pulsed current was applied to the pulsed copper coils to magnetize the bulk. The trapped field distribution and transient flux behaviour strongly depend on the radial dimension of the armature coil with a vortex-type winding. On decreasing the diameter of the pulsed copper armature coil, the distribution of the trapped flux density on the surface of the bulk becomes close to a conical shape. In contrast to the use of a solenoid, the application of vortex-type armature coils to magnetization of Gd-bulk HTS shows a quick intervention of the external magnetic flux into the centre of the bulk. The magnetization to the bulk HTS of the vortex-type copper coils with an optimum radius is useful and may be an effective technique for applied bulk HTS for rotating machines such as motors and/or generators

  13. 175 fs-long pulses from a high-power single-mode Er-doped fiber laser at 1550 nm

    Science.gov (United States)

    Elahi, Parviz; Kalaycıoğlu, Hamit; Li, Huihui; Akçaalan, Önder; Ilday, F. Ömer

    2017-11-01

    Development of Er-doped ultrafast lasers have lagged behind the corresponding developments in Yb- and Tm-doped lasers, in particular, fiber lasers. Various applications benefit from operation at a central wavelength of 1.5 μm and its second harmonic, including emerging applications such as 3D processing of silicon and 3D printing based on two-photon polymerization. We report a simple, robust fiber master oscillator power amplifier operating at 1.55 μm, implementing chirp pulse amplification using single-mode fibers for diffraction-limited beam quality. The laser generates 80 nJ pulses at a repetition rate of 43 MHz, corresponding to an average power of 3.5 W, which can be compressed down to 175 fs. The generation of short pulses was achieved using a design which is guided by numerical simulations of pulse propagation and amplification and manages to overturn gain narrowing with self-phase modulation, without invoking excessive Raman scattering processes. The seed source for the two-stage amplifier is a dispersion-managed passively mode-locked oscillator, which generates a ∼40 nm-wide spectrum and 1.7-ps linearly chirped pulses.

  14. A single 60-min bout of peristaltic pulse external pneumatic compression transiently upregulates phosphorylated ribosomal protein s6.

    Science.gov (United States)

    Martin, J S; Kephart, W C; Mobley, C B; Wilson, T J; Goodlett, M D; Roberts, M D

    2017-11-01

    We investigated whether a single 60-min bout of whole leg, peristaltic pulse external pneumatic compression (EPC) altered select growth factor-related mRNAs and/or various phospho(p)-proteins related to cell growth, proliferation, inflammation and apoptosis signalling (e.g. Akt-mTOR, Jak-Stat). Ten participants (8 males, 2 females; aged 22·2 ± 0·4 years) reported to the laboratory 4 h post-prandial, and vastus lateralis muscle biopsies were obtained prior to (PRE), 1 h and 4 h post-EPC treatment. mRNA expression was analysed using real-time RT-PCR and phosphophorylated and cleaved proteins were analysed using an antibody array. No changes in selected growth factor-related mRNAs were observed following EPC. All p-proteins significantly altered by EPC decreased, except for p-rps6 (Ser235/236) which increased 31% 1 h post-EPC compared to PRE levels (P = 0·016). Notable decreases also included p-BAD (Ser112; -28%, P = 0·004) at 4 h post-EPC compared to PRE levels. In summary, an acute bout of EPC transiently upregulates p-rps6 as well as affecting other markers in the Akt-mTOR signalling cascade. Future research should characterize whether chronic EPC application promotes alterations in lower-limb musculature and/or enhances exercise-induced training adaptations. © 2016 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

  15. Compact synchrotron radiation source

    International Nuclear Information System (INIS)

    Liu, N.; Wang, T.; Tian, J.; Lin, Y.; Chen, S.; He, W.; Hu, Y.; Li, Q.

    1985-01-01

    A compact 800 MeV synchrotron radiation source is discussed. The storage ring has a circumference of 30.3 m, two 90 degree and four 45 degree bending magnet sections, two long straight sections and four short straight sections. The radius of the bending magnet is 2.224m. The critical wave length is 24A. The injector is a 15 Mev Microtron Electrons are accelerated from 15 Mev to 800 Mev by ramping the field of the ring. The expected stored current will be around 100 ma

  16. The synchrotron radiation

    International Nuclear Information System (INIS)

    Chevallier, P.

    1994-01-01

    Synchrotron Radiation is a fantastic source of electromagnetic radiation the energy spectrum of which spreads continuously from the far infrared to hard X-rays. For this reason a wide part of the scientific community, fundamentalists as well as industry, is concerned by its use. We shall describe here the main properties of this light source and give two examples of application in the field of characterization of materials: EXAFS (Extended X-Ray Absorption Fine Structure) and X-ray fluorescence. (author). 8 figs., 21 refs

  17. Synchrotron radiation and applications

    International Nuclear Information System (INIS)

    Nenner, I.; Dexpert, H.; Bessiere, M.

    1989-01-01

    Synchrotron radiation gives a very large wavelength spectra from infrared to X-rays. The continuous spectra in the far ultraviolet and X rays and also the brightness of the source enlarge the studies of structural and electronic properties of matter. In a brief review of main applications, the paper presents more particularly absorption, diffusion and diffraction phenomena. Examples taken in inorganic chemistry and condensed matter physics show the power of X-ray aborption spectroscopy and electron spectroscopy methods (angular analysis of photoelectrons and mass spectroscopy) for the study of surfaces and solids. 51 refs [fr

  18. Synchrotron Moessbauer reflectometry

    Energy Technology Data Exchange (ETDEWEB)

    Nagy, D.L.; Bottyan, L.; Deak, L.; Szilagyi, E. [KFKI Research Institute for Particle and Nuclear Physics (Hungary); Spiering, H. [Johannes Gutenberg Universitaet Mainz, Institut fuer Anorganische und Analytische Chemie (Germany); Dekoster, J.; Langouche, G. [K.U. Leuven, Instituut voor Kern- en Stralingsfysica (Belgium)

    2000-07-15

    Grazing incidence nuclear resonant scattering of synchrotron radiation can be applied to perform depth-selective phase analysis and to determine the isotopic and magnetic structure of thin films and multilayers. Principles and recent experiments of this new kind of reflectometry are briefly reviewed. Methodological aspects are discussed. Model calculations demonstrate how the orientations of the sublattice magnetisation in ferro- and antiferromagnetic multilayers affect time-integral and time-differential spectra. Experimental examples show the efficiency of the method in investigating finite-stacking, in-plane and out-of-plane anisotropy and spin-flop effects in magnetic multilayers.

  19. Single-cycle terahertz pulses with >0.2 V/A field amplitudes via coherent transition radiation

    International Nuclear Information System (INIS)

    Daranciang, Dan; Goodfellow, John; Fuchs, Matthias; Ghimire, Shambhu; Wen, Haidan; Reis, David A.; Loos, Henrik; Fisher, Alan S.; Lindenberg, Aaron M.

    2011-01-01

    We demonstrate terahertz pulses with field amplitudes exceeding 0.2 V/A generated by coherent transition radiation. Femtosecond, relativistic electron bunches generated at the Linac Coherent Light Source are passed through a beryllium foil, and the emitted radiation is characterized as a function of the bunch duration and charge. Broadband pulses centered at a frequency of 10 THz with energies of 140 μJ are measured. These far-below-bandgap pulses drive a nonlinear optical response in a silicon photodiode, with which we perform nonlinear autocorrelations that yield information regarding the terahertz temporal profile. Simulations of the spatiotemporal profile agree well with experimental results.

  20. Phase lock of rapid cycling synchrotron and neutron choppers

    International Nuclear Information System (INIS)

    Praeg, W.; McGhee, D.; Volk, G.

    1981-01-01

    The 500-MeV synchrotron of Argonne's Intense Pulsed Neutron Source operates at 30 Hz. Its beam spill must be locked to neutron choppers with a precision of +- 0.5 μs. A chopper and an accelerator have large and different inertias. This makes synchronization by phase lock to the 60-Hz power line extremely difficult. We solved the phasing problems by running both the Ring Magnet Power Supply (RMPS) of the synchrotron and the chopper motors from a common oscillator that is stable to 1 ppM and by controlling five quantities of the RMPS. The quantities controlled by feedback loops are dc current, injection current, ejection current, resonant frequency, and the phase shift between the synchrotron peak field and the chopper window

  1. Investigation on a Novel Discontinuous Pulse-Width Modulation Algorithm for Single-phase Voltage Source Rectifier

    DEFF Research Database (Denmark)

    Qu, Hao; Yang, Xijun; Guo, Yougui

    2014-01-01

    Single-phase voltage source converter (VSC) is an important power electronic converter (PEC), including single-phase voltage source inverter (VSI), single-phase voltage source rectifier (VSR), single-phase active power filter (APF) and single-phase grid-connection inverter (GCI). Single-phase VSC...

  2. Synchrotrons and their applications in medical imaging and therapy

    International Nuclear Information System (INIS)

    Lewis, R.

    2004-01-01

    Full text: Australasia's first synchrotron is being built on the campus of Monash University near Melbourne. Is it of any relevance to the medical imaging and radiation therapy communities? The answer is an unequivocal yes. Synchrotrons overcome many of the problems with conventional X-ray sources and as a result make it possible to demonstrate extraordinary advances in both X-ray imaging and indeed in radio-therapy. Synchrotron imaging offers us a window into what is possible and the results are spectacular. Specific examples include lung images that reveal alveolar structure and computed tomography of single cells. For therapy treatments are being pioneered that seem to be effective on high grade gliomas. An overview of the status of medical applications using synchrotrons will be given and the proposed Australian medical imaging and therapy facilities will be described and some of the proposed research highlighted. Copyright (2004) Australasian College of Physical Scientists and Engineers in Medicine

  3. Single-pulse terahertz coherent control of spin resonance in the canted antiferromagnet YFeO3, mediated by dielectric anisotropy

    DEFF Research Database (Denmark)

    Jin, Zuanming; Mics, Zoltán; Ma, Guohong

    2013-01-01

    We report on the coherent control of terahertz (THz) spin waves in a canted antiferromagnet yttrium orthoferrite, YFeO3, associated with a quasiferromagnetic (quasi-FM) spin resonance at a frequency of 0.3 THz, using a single-incident THz pulse. The spin resonance is excited impulsively by the ma...... polarization of the THz oscillation at the spin resonance frequency, suggests a key role of magnon–phonon coupling in spin-wave energy dissipation....

  4. Lattice Design of a Medical Synchrotron

    Energy Technology Data Exchange (ETDEWEB)

    Jang, Ji Ho; Cho, Yong Sub; Kwon, Hyeok Jung [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Lee, Yong Yung [BNL, New York (United States)

    2010-05-15

    The proton therapy is a fast-growing method for a cancer treatment because it can concentrate proton beams into cancer cells and minimize damage on normal cells by using a Bragg peak. The design study on the synchrotron for the proton therapy is in progress as an R and D for using PEFP (proton engineering frontier project) accelerator technology. The injection energy is 3 MeV which is provided by an RFQ (radio frequency quadrupole). The maximum extraction energy is 250 MeV for treatment of deepest tumors in human body. It includes a slow extraction method through the third order resonance and a single turn extraction option. This brief report summarized the lattice design of the synchrotron

  5. Experience with synchrotron radiation sources

    International Nuclear Information System (INIS)

    Krinsky, S.

    1987-01-01

    The development of synchrotron radiation sources is discussed, emphasizing characteristics important for x-ray microscopy. Bending magnets, wigglers and undulators are considered as sources of radiation. Operating experience at the national Synchrotron Light Source on the VUV and XRAY storage rings is reviewed, with particular consideration given to achieved current and lifetime, transverse bunch dimensions, and orbit stability. 6 refs., 3 figs

  6. Synchrotron Elettra. Status and perspectives

    International Nuclear Information System (INIS)

    Remec, I.

    1992-01-01

    Synchrotron radiation and the possibilities for its applications are shortly presented. Elettra, the third generation synchrotron, now under construction in Trieste, Italy, is briefly described and its main characteristics are given. Current activities in Slovenia, related to Elettra, are presented. (author) [sl

  7. A novel molecular synchrotron for cold collision and EDM experiments.

    Science.gov (United States)

    Hou, Shunyong; Wei, Bin; Deng, Lianzhong; Yin, Jianping

    2016-09-07

    Limited by the construction demands, the state-of-the-art molecular synchrotrons consist of only 40 segments that hardly make a good circle. Imperfections in the circular structure will lead to the appearance of unstable velocity regions (i.e. stopbands), where molecules of certain forward velocity will be lost from the structure. In this paper, we propose a stopband-free molecular synchrotron. It contains 1570 ring electrodes, which nearly make a perfect circle, capable of confining both light and heavy polar molecules in the low-field-seeking states. Molecular packets can be conveniently manipulated with this synchrotron by various means, like acceleration, deceleration or even trapping. Trajectory calculations are carried out using a pulsed (88)SrF molecular beam with a forward velocity of 50 m/s. The results show that the molecular beam can make more than 500 round trips inside the synchrotron with a 1/e lifetime of 6.2 s. The synchrotron can find potential applications in low-energy collision and reaction experiments or in the field of precision measurements, such as the searches for electric dipole moment of elementary particles.

  8. Single-bunch kicker pulser

    International Nuclear Information System (INIS)

    Frey, W.W.

    1983-01-01

    The single-bunch kicker magnet is powered by a capacitor discharge pulser. The ferrite-core magnet is used to kick out one of twelve proton bunches circulating in the AGS (Alternating Gradient Synchrotron) into the experimental area. The magnet current pulse has a half-sinusoid shape, with a peak current of 2800 A. The pulse current rises and falls to zero, with minimum undershoot, in 410 nsec to minimize effects on adjacent bunches. The magnet inductance is 1.0 μHy. The pulser is mounted on the kicker magnet in the AGS ring, and is exposed to ionizing radiation. The HVDC power supply, controls, monitoring, and auxiliary circuits are housed approximately 300 feet away external to the ring. A two-gap thyratron is used to discharge the energy storage capacitor. Two hydrogen diodes are series connected to function as an inverse diode

  9. Single-bunch kicker pulser

    Energy Technology Data Exchange (ETDEWEB)

    Frey, W.W.

    1983-01-01

    The single-bunch kicker magnet is powered by a capacitor discharge pulser. The ferrite-core magnet is used to kick out one of twelve proton bunches circulating in the AGS (Alternating Gradient Synchrotron) into the experimental area. The magnet current pulse has a half-sinusoid shape, with a peak current of 2800 A. The pulse current rises and falls to zero, with minimum undershoot, in 410 nsec to minimize effects on adjacent bunches. The magnet inductance is 1.0 ..mu..Hy. The pulser is mounted on the kicker magnet in the AGS ring, and is exposed to ionizing radiation. The HVDC power supply, controls, monitoring, and auxiliary circuits are housed approximately 300 feet away external to the ring. A two-gap thyratron is used to discharge the energy storage capacitor. Two hydrogen diodes are series connected to function as an inverse diode.

  10. Terahertz Coherent Synchrotron Radiation in the MIT-Bates South Hall Ring

    CERN Document Server

    Wang, Fuhua; Cheever, Dan; Farkhondeh, Manouchehr; Franklin, Wilbur; Graves, William; Ihloff, Ernie; Podobedov, Boris; Sannibale, Fernando; Tschalär, C; Wang, Defa; Wang, Dong; Zwart, Townsend; van der Laan, Jan

    2005-01-01

    We investigate the terahertz coherent synchrotron radiation (CSR) potential of the South Hall Ring (SHR) at MIT-Bates Linear Accelerator Center. The SHR is equipped with a unique single cavity, 2.856 GHz RF system. The high RF frequency is advantageous for producing short bunch length and for having higher bunch current threshold to generate stable CSR. Combining with other techniques such as external pulse stacking cavity, femtosecond laser slicing, the potential for generating ultra-stable, high power, broadband terahertz CSR is very attractive. Beam dynamics issues related to short bunch length operation, and may associated with the high frequency RF system, such as multi-bunch instability are concerned. They could affect bunch length, bunch intensity and beam stability. The SHR is ideal for experimental exploration of these problems. Results of initial test of low momentum compaction lattice and bunch length measurements are presented and compared to expectations.

  11. Time-resolved materials science opportunities using synchrotron x-ray sources

    International Nuclear Information System (INIS)

    Larson, B.C.; Tischler, J.Z.

    1995-06-01

    The high brightness, high intensity, and pulsed time-structure of synchrotron sources provide new opportunities for time-resolved x-ray diffraction investigations. With third generation synchrotron sources coming on line, high brilliance and high brightness are now available in x-ray beams with the highest flux. In addition to the high average flux, the instantaneous flux available in synchrotron beams is greatly enhanced by the pulsed time structure, which consists of short bursts of x-rays that are separated by ∼tens to hundreds of nanoseconds. Time-resolved one- and two-dimensional position sensitive detection techniques that take advantage of synchrotron radiation for materials science x-ray diffraction investigations are presented, and time resolved materials science applications are discussed in terms of recent diffraction and spectroscopy results and materials research opportunities

  12. Longwave infrared, single-frequency, tunable, pulsed optical parametric oscillator based on orientation-patterned GaAs for gas sensing.

    Science.gov (United States)

    Clément, Q; Melkonian, J-M; Dherbecourt, J-B; Raybaut, M; Grisard, A; Lallier, E; Gérard, B; Faure, B; Souhaité, G; Godard, A

    2015-06-15

    We demonstrate a nanosecond single-frequency nested cavity optical parametric oscillator (NesCOPO) based on orientation-patterned GaAs (OP-GaAs). Its low threshold energy of 10 μJ enables to pump it with a pulsed single-frequency Tm:YAP microlaser. Stable single-longitudinal-mode emission is obtained owing to Vernier spectral filtering provided by the dual-cavity doubly-resonant NesCOPO scheme. Crystal temperature tuning covers the 10.3-10.9 μm range with a quasi-phase-matching period of 72.6 μm. A first step toward the implementation of this device in a differential absorption lidar is demonstrated by carrying out short-range standoff detection of ammonia vapor around 10.4 μm. Owing to the single-frequency emission, interferences due to absorption by atmospheric water vapor can be discriminated from the analyte signal.

  13. Proton synchrotron accelerator theory

    International Nuclear Information System (INIS)

    Wilson, E.J.N.

    1977-01-01

    This is the text of a series of lectures given as part of the CERN Academic Training Programme and primarily intended for young engineers and technicians in preparation for the running-in of the 400 GeV Super Proton Synchrotron (SPS). Following the definition of basic quantities, the problems of betatron motion and the effect of momentum spread and orbital errors on the transverse motion of the beam are reviewed. Consideration is then given to multipole fields, chromaticity and non-linear resonances. After dealing with basic relations governing longitudinal beam dynamics, the space-charge, resistive-wall and other collective effects are treated, with reference to precautions in the SPS to prevent their occurrence. (Auth.)

  14. Control circuits for the 1.3 GeV electron synchrotron

    International Nuclear Information System (INIS)

    Asaoka, S.; Shiino, K.; Yoshioka, M.; Norimura, K.

    1980-01-01

    Following control circuits for the 1.3 GeV electron synchrotron, Institute for Nuclear Study, University of Tokyo, have been designed and constructed. 1. Variable delay circuits for the timing pulse of the synchrotron. 2. An alarm circuit for sputter ion pumps. 3. A sample and hold circuit for digital display and computer control of the beam intensity. This report describes detailes of the circuits and their specificatons. (author)

  15. Dependence of single-shot pulse durations on near-infrared filamentation-guided breakdown in air

    Directory of Open Access Journals (Sweden)

    Andreas Schmitt-Sody

    2017-03-01

    Full Text Available We present results of an experimental investigation of laser pulsewidth dependence of filamentation-guided high voltage breakdown in air. The experiments are conducted at laser peak power levels of 1 TW and pulse durations of 0.7 to 10 ps with a discharge gap separation of 10 cm. Synchronized electrical and optical diagnostic techniques were used to determine the pulsewidth dependence on the breakdown mechanism, threshold levels, time delays and associated jitter. The results indicate that longer pulses provide greater than 30% reduction in breakdown threshold voltage.

  16. Formation of periodic mesoscale structures arranged in a circular symmetry at the silicon surface exposed to radiation of a single femtosecond laser pulse

    International Nuclear Information System (INIS)

    Romashevskiy, S.A.; Ashitkov, S.I.; Ovchinnikov, A.V.; Kondratenko, P.S.; Agranat, M.B.

    2016-01-01

    Graphical abstract: - Highlights: • Single pulse irradiation of silicon gave rise to the periodic mesoscale structures. • The number of the periodic structures depends on the incident laser fluence. • The theory of periodically modulated absorption of laser energy is proposed. - Abstract: The periodic mesoscale structures arranged in a circular symmetry were found at the silicon surface exposed to radiation of the single femtosecond laser pulse with a Gaussian intensity profile in the ambient air conditions. These peculiar structures have the appearance of the protrusions of ∼10 nm height and of ∼600 nm width (at a FWHM) separately located inside the ablated region with a period of the incident laser wavelength. It was found that their position at the surface corresponds to the specified laser intensity slightly above the ablation threshold. The number of the formed periodic structures varies with the fluence of the incident laser pulse and in our experiments it was found to have changed from one to eleven. We suppose that formation of these mesoscale structures is caused by heating of a microscale volume to the strongly defined temperature. The theoretical model was proposed to explain the obtained data. It assumes that the interference of incident laser radiation with laser-induced surface electromagnetic waves results in generation of periodic distribution of electron temperature. Thus formation of the periodic structures at the specified laser intensity is attributed to periodically modulated absorption of laser energy at a focal laser spot.

  17. Synchrotron Intensity Gradients as Tracers of Interstellar Magnetic Fields

    International Nuclear Information System (INIS)

    Lazarian, A.; Yuen, Ka Ho; Lee, Hyeseung; Cho, J.

    2017-01-01

    On the basis of the modern understanding of MHD turbulence, we propose a new way of using synchrotron radiation: using synchrotron intensity gradients (SIGs) for tracing astrophysical magnetic fields. We successfully test the new technique using synthetic data obtained with 3D MHD simulations and provide the demonstration of the practical utility of the technique by comparing the directions of magnetic fields that are obtained with PLANCK synchrotron intensity data to the directions obtained with PLANCK synchrotron polarization data. We demonstrate that the SIGs can reliably trace magnetic fields in the presence of noise and can provide detailed maps of magnetic field directions. We also show that the SIGs are relatively robust for tracing magnetic fields while the low spatial frequencies of the synchrotron image are removed. This makes the SIGs applicable to the tracing of magnetic fields using interferometric data with single-dish measurement absent. We discuss the synergy of using the SIGs together with synchrotron polarization in order to find the actual direction of the magnetic fields and quantify the effects of Faraday rotation as well as with other ways of studying astrophysical magnetic fields. We test our method in the presence of noise and the resolution effects. We stress the complementary nature of the studies using the SIG technique and those employing the recently introduced velocity gradient techniques that trace magnetic fields using spectroscopic data.

  18. Synchrotron Intensity Gradients as Tracers of Interstellar Magnetic Fields

    Science.gov (United States)

    Lazarian, A.; Yuen, Ka Ho; Lee, Hyeseung; Cho, J.

    2017-06-01

    On the basis of the modern understanding of MHD turbulence, we propose a new way of using synchrotron radiation: using synchrotron intensity gradients (SIGs) for tracing astrophysical magnetic fields. We successfully test the new technique using synthetic data obtained with 3D MHD simulations and provide the demonstration of the practical utility of the technique by comparing the directions of magnetic fields that are obtained with PLANCK synchrotron intensity data to the directions obtained with PLANCK synchrotron polarization data. We demonstrate that the SIGs can reliably trace magnetic fields in the presence of noise and can provide detailed maps of magnetic field directions. We also show that the SIGs are relatively robust for tracing magnetic fields while the low spatial frequencies of the synchrotron image are removed. This makes the SIGs applicable to the tracing of magnetic fields using interferometric data with single-dish measurement absent. We discuss the synergy of using the SIGs together with synchrotron polarization in order to find the actual direction of the magnetic fields and quantify the effects of Faraday rotation as well as with other ways of studying astrophysical magnetic fields. We test our method in the presence of noise and the resolution effects. We stress the complementary nature of the studies using the SIG technique and those employing the recently introduced velocity gradient techniques that trace magnetic fields using spectroscopic data.

  19. Synchrotron Intensity Gradients as Tracers of Interstellar Magnetic Fields

    Energy Technology Data Exchange (ETDEWEB)

    Lazarian, A.; Yuen, Ka Ho; Lee, Hyeseung; Cho, J. [Department of Astronomy, University of Wisconsin-Madison, 2535 Sterling Hall, 475 North Charter Street, Madison, WI 53706-1507 (United States)

    2017-06-10

    On the basis of the modern understanding of MHD turbulence, we propose a new way of using synchrotron radiation: using synchrotron intensity gradients (SIGs) for tracing astrophysical magnetic fields. We successfully test the new technique using synthetic data obtained with 3D MHD simulations and provide the demonstration of the practical utility of the technique by comparing the directions of magnetic fields that are obtained with PLANCK synchrotron intensity data to the directions obtained with PLANCK synchrotron polarization data. We demonstrate that the SIGs can reliably trace magnetic fields in the presence of noise and can provide detailed maps of magnetic field directions. We also show that the SIGs are relatively robust for tracing magnetic fields while the low spatial frequencies of the synchrotron image are removed. This makes the SIGs applicable to the tracing of magnetic fields using interferometric data with single-dish measurement absent. We discuss the synergy of using the SIGs together with synchrotron polarization in order to find the actual direction of the magnetic fields and quantify the effects of Faraday rotation as well as with other ways of studying astrophysical magnetic fields. We test our method in the presence of noise and the resolution effects. We stress the complementary nature of the studies using the SIG technique and those employing the recently introduced velocity gradient techniques that trace magnetic fields using spectroscopic data.

  20. The European Synchrotron Radiation Facility

    DEFF Research Database (Denmark)

    Buras, B.; Materlik, G.

    1986-01-01

    In recent years, X-ray synchrotron radiation became a powerful tool for studies of condensed matter, and in view of that a proposal for the construction of a European Synchrotron Radiation Facility (ESRF) was elaborated in some detail by the European Synchrotron Radiation Project. The heart...... by a great flexibility and a small emittance (7×10−9 rad m) leading to a very high brilliance (1019 photons/(s mm2 mrad2) in a relative bandwidth of 0.1% in case of a 1 Å undulator). The overview, as seen from the users point of view, gives a brief account of the storage ring, emitted radiation...

  1. Description and verification of an algorithm for obtaining microdosimetric quantities for high-LET radiation using a single TEPC without pulse height analysis.

    Science.gov (United States)

    Borak, Thomas B; Chapman, Phillip L

    2014-10-01

    Microdosimetric spectra of single event distributions have been used to provide estimates of quality factors for radiation protection of high-LET radiation. In situations with high-dose rates it becomes difficult to measure, record and store energy deposition from single events. An alternative approach is to store random energy deposition events in a sequence of fixed time intervals that does not require identifying from single events. This can be accomplished with a single detector without pulse height analysis. We show the development of the algorithm using expectation analysis of the statistical estimators for moments of lineal energy: ȳf and ȳD. The method was tested using Monte Carlo simulations based on single event distributions measured with spherical tissue equivalent proportional counters where the event sizes spanned more than two orders of magnitude. The evaluation included testing at various mean numbers of events per interval (i.e., dose rate) and numbers of intervals (i.e., total duration). Results of the expectation analysis and Monte Carlo simulation showed that the algorithm corrects for the excess dispersion due to the random number of events in each time interval when the underlying dose rate is constant. It also converges to the correct value when there is a linear trend in dose rate of the duration of the measurement process. Although this system is not applicable for pulsed radiation fields it proved to be robust when applied to measured distributions with single event spectra (PuBe neutrons, Fe ions at 1,000 MeV/nucleon and a power function distribution of single event sizes) with a coefficient of variation of 25% for estimates of ȳD using 100 sampling intervals and 10% using 400 sampling intervals.

  2. Cardiac imaging at 7 Tesla: Single- and two-spoke radiofrequency pulse design with 16-channel parallel excitation.

    Science.gov (United States)

    Schmitter, Sebastian; DelaBarre, Lance; Wu, Xiaoping; Greiser, Andreas; Wang, Dingxin; Auerbach, Edward J; Vaughan, J Thomas; Uğurbil, Kâmil; Van de Moortele, Pierre-François

    2013-11-01

    Higher signal to noise ratio (SNR) and improved contrast have been demonstrated at ultra-high magnetic fields (≥7 Tesla [T]) in multiple targets, often with multi-channel transmit methods to address the deleterious impact on tissue contrast due to spatial variations in B1 (+) profiles. When imaging the heart at 7T, however, respiratory and cardiac motion, as well as B0 inhomogeneity, greatly increase the methodological challenge. In this study we compare two-spoke parallel transmit (pTX) RF pulses with static B1 (+) shimming in cardiac imaging at 7T. Using a 16-channel pTX system, slice-selective two-spoke pTX pulses and static B1 (+) shimming were applied in cardiac CINE imaging. B1 (+) and B0 mapping required modified cardiac triggered sequences. Excitation homogeneity and RF energy were compared in different imaging orientations. Two-spoke pulses provide higher excitation homogeneity than B1 (+) shimming, especially in the more challenging posterior region of the heart. The peak value of channel-wise RF energy was reduced, allowing for a higher flip angle, hence increased tissue contrast. Image quality with two-spoke excitation proved to be stable throughout the entire cardiac cycle. Two-spoke pTX excitation has been successfully demonstrated in the human heart at 7T, with improved image quality and reduced RF pulse energy when compared with B1 (+) shimming. Copyright © 2013 Wiley Periodicals, Inc.

  3. Homogenization optics to improve detectability of a fluorescence response to a single laser pulse: Detection of feces on apples

    Science.gov (United States)

    Fecal contamination of produce is a known food safety risk. Measuring fluorescence responses to UV excitation is an established method for detecting such contamination. One measurement system utilizes a pulsed UV laser to induce a fluorescence response from fecal material and a gated intensified cam...

  4. Single-pass waveguide amplifiers in Er-Yb doped zinc polyphosphate glass fabricated with femtosecond laser pulses

    NARCIS (Netherlands)

    Fletcher, L.B.; Witcher, J.J.; Troy, N.; Brow, R.K.; Krol, D.M.

    2012-01-01

    We have investigated the direct fabrication of subsurface waveguide amplifiers in Er-Yb zinc polyphosphate glass by utilizing the relationship between the initial glass composition and the resulting changes to the network structure after modification by fs laser pulses. Waveguides, exhibiting

  5. Single-shot all-optical sampling oscilloscope using a polarization-maintaining resonator for pulse replication

    Czech Academy of Sciences Publication Activity Database

    Komanec, M.; Honzátko, Pavel; Zvánovec, S.

    2010-01-01

    Roč. 52, č. 11 (2010), s. 2452-2456 ISSN 0895-2477 R&D Projects: GA AV ČR 1ET300670502 Institutional research plan: CEZ:AV0Z20670512 Keywords : optical sampling oscilloscope * four-wave mixing * fiber pulse replicator * highly nonlinear fiber Subject RIV: BH - Optics, Masers, Lasers Impact factor: 0.656, year: 2010

  6. Broadband single-transverse-mode fluorescence sources based on ribs fabricated in pulsed laser deposited Ti: sapphire waveguides

    NARCIS (Netherlands)

    Grivas, C.; May-Smith, T.C.; Shepherd, D.P.; Eason, R.W.; Pollnau, Markus; Jelinek, M.

    2004-01-01

    Active rib waveguides with depths and widths varying from 3 to 5 μm and from 9 to 24 μm, respectively, have been structured by $Ar^{+}$-beam etching in pulsed laser deposited Ti:sapphire layers. Losses in the channel structures were essentially at the same levels as the unstructured planar waveguide

  7. Front-surface fabrication of moderate aspect ratio micro-channels in fused silica by single picosecond Gaussian-Bessel laser pulse

    Science.gov (United States)

    Liu, Xin; Sanner, Nicolas; Sentis, Marc; Stoian, Razvan; Zhao, Wei; Cheng, Guanghua; Utéza, Olivier

    2018-02-01

    Single-shot Gaussian-Bessel laser beams of 1 ps pulse duration and of 0.9 μm core size and 60 μm depth of focus are used for drilling micro-channels on front side of fused silica in ambient condition. Channels ablated at different pulse energies are fully characterized by AFM and post-processing polishing procedures. We identify experimental energy conditions (typically 1.5 µJ) suitable to fabricate non-tapered channels with mean diameter of 1.2 µm and length of 40 μm while maintaining an utmost quality of the front opening of the channels. In addition, by further applying accurate post-polishing procedure, channels with high surface quality and moderate aspect ratio down to a few units are accessible, which would find interest in the surface micro-structuring of materials, with perspective of further scalability to meta-material specifications.

  8. Integrated Method for Purification and Single-Particle Characterization of Lentiviral Vector Systems by Size Exclusion Chromatography and Tunable Resistive Pulse Sensing.

    Science.gov (United States)

    Heider, Susanne; Muzard, Julien; Zaruba, Marianne; Metzner, Christoph

    2017-07-01

    Elements derived from lentiviral particles such as viral vectors or virus-like particles are commonly used for biotechnological and biomedical applications, for example in mammalian protein expression, gene delivery or therapy, and vaccine development. Preparations of high purity are necessary in most cases, especially for clinical applications. For purification, a wide range of methods are available, from density gradient centrifugation to affinity chromatography. In this study we have employed size exclusion columns specifically designed for the easy purification of extracellular vesicles including exosomes. In addition to viral marker protein and total protein analysis, a well-established single-particle characterization technology, termed tunable resistive pulse sensing, was employed to analyze fractions of highest particle load and purity and characterize the preparations by size and surface charge/electrophoretic mobility. With this study, we propose an integrated platform combining size exclusion chromatography and tunable resistive pulse sensing for monitoring production and purification of viral particles.

  9. Design and Construction of an Autonomous Low-Cost Pulse Height Analyzer and a Single Channel Analyzer for Mössbauer Spectroscopy

    Science.gov (United States)

    Velásquez, A. A.; Gancedo, J. R.; Trujillo, J. M.; Morales, A. L.; Tobón, J. E.; Reyes, L.

    2005-04-01

    A multichannel analyzer (MCA) and a single channel-analyzer (SCA) for Mössbauer spectrometry application have been designed and built. Both systems include low-cost digital and analog components. A microcontroller manages, either in PHA or MCS mode, the data acquisition, data storage and setting of the pulse discriminator limits. The user can monitor the system from an external PC through the serial port with the RS232 communication protocol. A graphic interface made with the LabVIEW software allows the user to adjust digitally the lower and upper limits of the pulse discriminator, and to visualize as well as save the PHA spectra in a file. The system has been tested using a 57Co radioactive source and several iron compounds, yielding satisfactory results. The low cost of its design, construction and maintenance make this equipment an attractive choice when assembling a Mössbauer spectrometer.

  10. Assessment of high-power kW-class single-diode bars for use in highly efficient pulsed solid state laser systems

    Science.gov (United States)

    Lucianetti, Antonio; Pilar, Jan; Pranovich, Alina; Divoky, Martin; Mocek, Tomas; Ertel, K.; Jelinkova, Helena; Crump, P.; Frevert, C.; Staske, R.; Erbert, Götz; Traenkle, Günther

    2015-03-01

    In this work, we present measurements of efficiency-optimized 940 nm diode laser bars with long resonators that are constructed with robustly passivated output facets at the Ferdinand-Braun-Institut (FBH). The measurements were performed at room temperature on a test bench developed at HiLASE Centre, as a function of operating condition. The single-diode bars generated < 1.0 kW when tested with 1 ms pulses at 1-10Hz operating frequency, corresponding to < 1 J per pulse. The maximum electrical-to-optical efficiency was < 60 %, with operating efficiency at 1 kW of < 50%, limited by the ~ 200 μΩ resistance of the bar packaging. In addition, slow axis divergence at 1 kW was below 6° FWHM and spectral width at 1 kW was below 7 nm FWHM, as needed for pumping Yb-doped solid state amplifier crystals.

  11. A dense plasma focus-based neutron source for a single-shot detection of illicit materials and explosives by a nanosecond neutron pulse

    Energy Technology Data Exchange (ETDEWEB)

    Gribkov, V A; Latyshev, S V [Institute of Theoretical and Experimental Physics, Moscow (Russian Federation); Miklaszewski, R A; Chernyshova, M [Institute of Plasma Physics and Laser Microfusion, Warsaw (Poland); Drozdowicz, K; Wiacek, U [Institute of Nuclear Physics, Krakow (Poland); Tomaszewski, K [ACS Ltd, Warsaw (Poland); Lemeshko, B D [N L Dukhov All-Russian Institute of Automation, Moscow (Russian Federation)], E-mail: gribkovv@yahoo.com

    2010-03-15

    Recent progress in a single-pulse Nanosecond Impulse Neutron Investigation System (NINIS) intended for interrogation of hidden objects by means of measuring elastically scattered neutrons is presented in this paper. The method uses very bright neutron pulses having duration of the order of 10 ns only, which are generated by dense plasma focus (DPF) devices filled with pure deuterium or DT mixture as a working gas. The small size occupied by the neutron bunch in space, number of neutrons per pulse and mono-chromaticity ({delta}E/E{approx}1%) of the neutron spectrum provides the opportunity to use a time-of-flight (TOF) technique with flying bases of about a few metres. In our researches we used DPF devices having bank energy in the range 2-7 kJ. The devices generate a neutron yield of the level of 10{sup 8}-10{sup 9} 2.45 MeV and 10{sup 10}-10{sup 11} 14 MeV neutrons per pulse with pulse duration {approx}10-20 ns. TOF base in the tests was 2.2-18.5 m. We have demonstrated the possibility of registering of neutrons scattered by the substances under investigation-1 litre bottles with methanol (CH{sub 3}OH), phosphoric (H{sub 2}PO{sub 4}) and nitric (HNO{sub 3}) acids as well as a long object-a 1 m gas tank filled with deuterium at high pressure. It is shown that the above mentioned short TOF bases and relatively low neutron yields are enough to distinguish different elements' nuclei composing the substance under interrogation and to characterize the geometry of lengthy objects in some cases. The wavelet technique was employed to 'clean' the experimental data registered. The advantages and restrictions of the proposed and tested NINIS technique in comparison with other methods are discussed.

  12. A dense plasma focus-based neutron source for a single-shot detection of illicit materials and explosives by a nanosecond neutron pulse

    International Nuclear Information System (INIS)

    Gribkov, V A; Latyshev, S V; Miklaszewski, R A; Chernyshova, M; Drozdowicz, K; Wiacek, U; Tomaszewski, K; Lemeshko, B D

    2010-01-01

    Recent progress in a single-pulse Nanosecond Impulse Neutron Investigation System (NINIS) intended for interrogation of hidden objects by means of measuring elastically scattered neutrons is presented in this paper. The method uses very bright neutron pulses having duration of the order of 10 ns only, which are generated by dense plasma focus (DPF) devices filled with pure deuterium or DT mixture as a working gas. The small size occupied by the neutron bunch in space, number of neutrons per pulse and mono-chromaticity (ΔE/E∼1%) of the neutron spectrum provides the opportunity to use a time-of-flight (TOF) technique with flying bases of about a few metres. In our researches we used DPF devices having bank energy in the range 2-7 kJ. The devices generate a neutron yield of the level of 10 8 -10 9 2.45 MeV and 10 10 -10 11 14 MeV neutrons per pulse with pulse duration ∼10-20 ns. TOF base in the tests was 2.2-18.5 m. We have demonstrated the possibility of registering of neutrons scattered by the substances under investigation-1 litre bottles with methanol (CH 3 OH), phosphoric (H 2 PO 4 ) and nitric (HNO 3 ) acids as well as a long object-a 1 m gas tank filled with deuterium at high pressure. It is shown that the above mentioned short TOF bases and relatively low neutron yields are enough to distinguish different elements' nuclei composing the substance under interrogation and to characterize the geometry of lengthy objects in some cases. The wavelet technique was employed to 'clean' the experimental data registered. The advantages and restrictions of the proposed and tested NINIS technique in comparison with other methods are discussed.

  13. A dense plasma focus-based neutron source for a single-shot detection of illicit materials and explosives by a nanosecond neutron pulse

    Science.gov (United States)

    Gribkov, V. A.; Latyshev, S. V.; Miklaszewski, R. A.; Chernyshova, M.; Drozdowicz, K.; Wiącek, U.; Tomaszewski, K.; Lemeshko, B. D.

    2010-03-01

    Recent progress in a single-pulse Nanosecond Impulse Neutron Investigation System (NINIS) intended for interrogation of hidden objects by means of measuring elastically scattered neutrons is presented in this paper. The method uses very bright neutron pulses having duration of the order of 10 ns only, which are generated by dense plasma focus (DPF) devices filled with pure deuterium or DT mixture as a working gas. The small size occupied by the neutron bunch in space, number of neutrons per pulse and mono-chromaticity (ΔE/E~1%) of the neutron spectrum provides the opportunity to use a time-of-flight (TOF) technique with flying bases of about a few metres. In our researches we used DPF devices having bank energy in the range 2-7 kJ. The devices generate a neutron yield of the level of 108-109 2.45 MeV and 1010-1011 14 MeV neutrons per pulse with pulse duration ~10-20 ns. TOF base in the tests was 2.2-18.5 m. We have demonstrated the possibility of registering of neutrons scattered by the substances under investigation—1 litre bottles with methanol (CH3OH), phosphoric (H2PO4) and nitric (HNO3) acids as well as a long object—a 1 m gas tank filled with deuterium at high pressure. It is shown that the above mentioned short TOF bases and relatively low neutron yields are enough to distinguish different elements' nuclei composing the substance under interrogation and to characterize the geometry of lengthy objects in some cases. The wavelet technique was employed to 'clean' the experimental data registered. The advantages and restrictions of the proposed and tested NINIS technique in comparison with other methods are discussed.

  14. Advanced Synchrotron Techniques at High Pressure Collaborative Access Team (HPCAT)

    Science.gov (United States)

    Shen, G.; Sinogeikin, S. V.; Chow, P.; Kono, Y.; Meng, Y.; Park, C.; Popov, D.; Rod, E.; Smith, J.; Xiao, Y.; Mao, H.

    2012-12-01

    High Pressure Collaborative Access Team (HPCAT) is dedicated to advancing cutting-edge, multidisciplinary, high-pressure science and technology using synchrotron radiation at Sector 16 of the Advanced Photon Source (APS) of Argonne National Laboratory. At HPCAT an array of novel x-ray diffraction and spectroscopic techniques has been integrated with high pressure and extreme temperature instrumentation for studies of structure and materials properties at extreme conditions.. HPCAT consists of four active independent beamlines performing a large range of various experiments at extreme conditions. 16BM-B beamline is dedicated to energy dispersive and white Laue X-ray diffraction. The majority of experiments are performed with a Paris-Edinburgh large volume press (to 7GPa and 2500K) and include amorphous and liquid structure measurement, white beam radiography, elastic sound wave velocity measurement of amorphous solid materials, with viscosity and density measurement of liquid being under development. 16BM-D is a monochromatic diffraction beamline for powder and single crystal diffraction at high pressure and high (resistive heating) / low (cryostats) temperature. The additional capabilities include high-resolution powder diffraction and x-ray absorption near edge structure (XANES) spectroscopy. The insertion device beamline of HPCAT has two undulators in canted mode (operating independently) and LN cooled Si monochromators capable of providing a large range of energies. 16IDB is a microdiffraction beamline mainly focusing on high-pressure powder and single crystal diffraction in DAC at high temperatures (double-sided laser heating and resistive heating) and low temperature (various cryostats). The modern instrumentation allows high-quality diffraction at megabar pressures from light element, fast experiments with pulsed laser heating, fast dynamic experiments with Pilatus detector, and so on. 16ID-D beamline is dedicated to x-ray scattering and spectroscopy research

  15. Progress in multi-element silicon detectors for synchrotron XRF applications

    International Nuclear Information System (INIS)

    Ludewigt, B.; Rossington, C.; Kipnis, I.; Krieger, B.

    1995-10-01

    Multi-element silicon strip detectors, in conjunction with integrated circuit pulse-processing electronics, offer an attractive alternative to conventional lithium-drifted silicon and high purity germanium detectors for high count rate, low noise synchrotron x-ray fluorescence applications. We have been developing these types of detectors specifically for low noise synchrotron applications, such as extended x-ray absorption fine structure spectroscopy, microprobe x-ray fluorescence and total reflection x-ray fluorescence. The current version of the 192-element detector and integrated circuit preamplifier, cooled to -25 degrees C with a single-stage thermoelectric cooler, achieves an energy resolution of <200 eV full width of half maximum (FWHM) per channel (at 5.9 keV, 2 μs peaking time), and each detector element is designed to handle ∼20 kHz count rate. The detector system will soon be completed to 64 channels using new application specific integrated circuit (ASIC) amplifier chips, new CAMAC (Computer Automated Measurement and Control standard) analog-to-digital converters recently developed at Lawrence Berkeley National Laboratory (LBNL), CAMAC histogramming modules, and Macintosh-based data acquisition software. We report on the characteristics of this detector system, and the work in progress towards the next generation system

  16. Computational study of the afterglow in single and sequential pulsing of an atmospheric-pressure plasma jet

    Science.gov (United States)

    Hasan, M. I.; Bradley, J. W.

    2015-10-01

    The spatial distribution of charged species in the afterglow of a helium plasma jet impinging atmospheric air has been computed using a 2D axisymmetric fluid model. The model is solved for two consecutive pulse periods of a rectangular voltage waveform (duration of 60 ns) and for two different frequencies (25 and 50 kHz). The most abundant ionic species in the afterglow are found to be \\text{O}2+ and \\text{O}2- with their concentrations increasing by about an order of magnitude (up to about 1018 m-3 and 1017 m-3 respectively) in the initial 1 μs. In the first pulse, these species form a halo around the diffusing He+ and electron rich central channel, the shape of the former being strongly correlated with the shape of He-air mixing layer computed using a hydrodynamic model. In the next pulse, this general configuration is also observed; however \\text{O}2+ is more concentrated on the axis of the jet, this being due to influence of residual electrons in the central channel. For \\text{O}2- there is little difference in their spatial distribution compared to the initial pulse. For higher frequency pulsing, the higher concentration of residual electrons lowers the necessary ignition electric field reducing the concentrations (by 25%) of charged species in a period of the applied waveform. This work provides new information on the concentration and distribution of ionic species generated by atmospheric-pressure capillary discharges of interest to those developing such sources for range of applications, particularly in the field of plasma medicine.

  17. Pulsed, tunable, single-frequency OP-GaAs OPO for the standoff detection of hazardous chemicals in the longwave infrared

    Science.gov (United States)

    Clément, Q.; Melkonian, J.-M.; Dherbecourt, J.-B.; Raybaut, M.; Grisard, A.; Lallier, E.; Gérard, B.; Faure, B.; Souhaité, G.; Godard, A.

    2015-10-01

    We present our results on the first nanosecond single-frequency optical parametric oscillator (OPO) emitting in the longwave infrared. It is based on orientation-patterned GaAs (OP-GaAs), and can be pumped by a pulsed singlefrequency Tm:YAP microlaser thanks to its low oscillation threshold of 10 μJ. Stable single-longitudinal mode emission of the OPO is obtained owing to Vernier spectral filtering provided by its nested cavity OPO (NesCOPO) scheme. Crystal temperature tuning covers the 10.3-10.9 μm range with a single quasi-phase-matching period of 72.6 μm. Shortrange standoff detection of ammonia vapor around 10.4 μm is performed with this source. We believe that this achievement paves the way to differential absorption lidars in the LWIR with increased robustness and reduced footprint.

  18. Inverse comptonization vs. thermal synchrotron

    International Nuclear Information System (INIS)

    Fenimore, E.E.; Klebesadel, R.W.; Laros, J.G.

    1983-01-01

    There are currently two radiation mechanisms being considered for gamma-ray bursts: thermal synchrotron and inverse comptonization. They are mutually exclusive since thermal synchrotron requires a magnetic field of approx. 10 12 Gauss whereas inverse comptonization cannot produce a monotonic spectrum if the field is larger than 10 11 and is too inefficient relative to thermal synchrotron unless the field is less than 10 9 Gauss. Neither mechanism can explain completely the observed characteristics of gamma-ray bursts. However, we conclude that thermal synchrotron is more consistent with the observations if the sources are approx. 40 kpc away whereas inverse comptonization is more consistent if they are approx. 300 pc away. Unfortunately, the source distance is still not known and, thus, the radiation mechanism is still uncertain

  19. Regions compete for French synchrotron

    CERN Multimedia

    2000-01-01

    Ten regions in France have placed bids to host the planned national synchrotron Soleil. Leading contenders include a joint bid from Ile-de-France and Essonne for Orsay, offering FF 1 billion towards the construction costs (2 paragraphs).

  20. Proton synchrotrons for cancer therapy

    CERN Document Server

    Coutrakon, G

    2000-01-01

    Synchrotrons offer several advantages over linear accelerators and cyclotrons for cancer treatment. Their compact size, low radiation shielding requirements, and ease of energy control make them ideally suited to this application. In this paper, we examine the requirements for therapy machines and compare the capabilities of linear accelerators, cyclotrons, and synchrotrons, which are currently being used, or are in development, for cancer treatment. At Loma Linda University Medical Center, a 250-MeV proton synchrotron has been in use to treat more than five thousand patients in the last 10 yr. The capabilities of this accelerator will be presented as well as some of the new synchrotrons which are being built or designed for future therapy applications. (0 refs).

  1. Synchrotron light source data book

    International Nuclear Information System (INIS)

    Murphy, J.

    1989-01-01

    The ''Synchrotron Light Source Data Book'' is as its name implies a collection of data on existing and planned synchrotron light sources. The intention was to provide a compendium of tools for the design of electron storage rings as synchrotron radiation sources. The slant is toward the accelerator physicist as other booklets such as the X-ray Data Booklet, edited by D. Vaughan (LBL PUB-490), address the 'use' of synchrotron radiation. It is hoped that the booklet serves as a pocket sized reference to facilitate back of the envelope type calculations. It contains some useful formulae in 'practical units' and a brief description of many of the existing and planned light source lattices

  2. Reshuffle lifts French synchrotron hopes

    CERN Multimedia

    McCabe, H

    2000-01-01

    The sacking of Claude Allegre as research minister has raised doubts over the level of France's promised participation in the construction of Diamond but reawakened French hopes that the synchrotron Soleil may now be built (1 page).

  3. Glancing angle synchrotron X-ray diffraction

    International Nuclear Information System (INIS)

    Cernik, R.J.

    1996-01-01

    This paper describes in basic detail some of the techniques that can be used to study thin films and surfaces. These are all in the X-ray region and cover reflectivity, diffraction form polycrystalline films, textured films and single crystal films. Other effects such as fluorescence and diffuse scattering are mentioned but not discussed in detail. Two examples of the reflectivity from multilayers and the diffraction from iron oxide films are discussed. The advantages of the synchrotron for these studies is stressed and the experimental geometries that can be employed are described i detail. A brief bibliography is provided at the end to accompany this part of the 1996 Frascati school

  4. Glancing angle synchrotron X-ray diffraction

    Energy Technology Data Exchange (ETDEWEB)

    Cernik, R.J. [Daresbury Lab., Warrington, WA (United States)

    1996-09-01

    This paper describes in basic detail some of the techniques that can be used to study thin films and surfaces. These are all in the X-ray region and cover reflectivity, diffraction form polycrystalline films, textured films and single crystal films. Other effects such as fluorescence and diffuse scattering are mentioned but not discussed in detail. Two examples of the reflectivity from multilayers and the diffraction from iron oxide films are discussed. The advantages of the synchrotron for these studies is stressed and the experimental geometries that can be employed are described i detail. A brief bibliography is provided at the end to accompany this part of the 1996 Frascati school.

  5. Single-pulse measurement of density and temperature in a turbulent, supersonic flow using UV laser spectroscopy

    Science.gov (United States)

    Fletcher, D. G.; Mckenzie, R. L.

    1992-01-01

    Nonintrusive measurements of density and temperature and their turbulent fluctuation levels have been obtained in the boundary layer of an unseeded, Mach 2 wind tunnel flow. The spectroscopic technique that was used to make the measurements is based on the combination of laser-induced oxygen fluorescence and Raman scattering by oxygen and nitrogen from the same laser pulse. Results from this demonstration experiment compare favorably with previous measurements obtained in the same facility from conventional probes and an earlier spectroscopic technique.

  6. XPEEM spectro-microscopy using synchrotron radiation; La spectromicroscopie XPEEM avec le rayonnement synchrotron

    Energy Technology Data Exchange (ETDEWEB)

    Barrett, N. [CEA Saclay (DSM/IRAMIS/SPCSI), 91 - Gif-sur-Yvette (France); Renault, O. [CEA Grenoble, Lab. d' Electronique et de Technologie de l' Informatique (LETI), Minatec, 38 (France)

    2009-07-01

    Synchrotron radiation offers new dimensions to photoelectron spectroscopy. Third generation synchrotron radiation sources offer optimization of the photoionization cross-sections and surface sensitivity, as well as the availability of high brilliance photon beams. Angularly resolved photoelectron spectroscopy (ARPES) can do band mapping of single crystal electronic structure. X-ray photoelectron spectroscopy (XPS) probes the chemical environment of constituent atoms. With respect to ARPES and XPS, photoelectron emission microscopy (PEEM) conserves the spatial origin of the photoelectrons thanks to electron optics which collect, focus and enlarges the photoelectric signal. The ultimate spatial resolution is determined by electron diffraction and the chromatic and spherical aberrations. Synchrotron radiation is therefore well adapted to finding the necessary compromise between aberration minimization using apertures and the microscope transmission for full spectroscopic PEEM. We present the perspectives for spectral reconstruction of submicron zones of samples having chemical, elemental or electronic inhomogeneities with a spatial resolution between 50 and 100 nm. Several examples will illustrate the potential of the technique: molecular grafting; chemical imaging of single nano-wires and polycrystalline structures. (authors)

  7. Comparison of photobiomodulation therapy and suprascapular nerve-pulsed radiofrequency in chronic shoulder pain: a randomized controlled, single-blind, clinical trial.

    Science.gov (United States)

    Ökmen, Burcu Metin; Ökmen, Korgün

    2017-11-01

    Shoulder pain can be difficult to treat due to its complex anatomic structure, and different treatment methods can be used. We aimed to examine the efficacy of photobiomodulation therapy (PBMT) and suprascapular nerve (SSN)-pulsed radiofrequency (RF) therapy. In this prospective, randomized, controlled, single-blind study, 59 patients with chronic shoulder pain due to impingement syndrome received PBMT (group H) or SSN-pulsed RF therapy (group P) in addition to exercise therapy for 14 sessions over 2 weeks. Records were taken using visual analog scale (VAS), Shoulder Pain and Disability Index (SPADI), and Nottingham Health Profile (NHP) scoring systems for pretreatment (PRT), posttreatment (PST), and PST follow-up at months 1, 3, and 6. There was no statistically significant difference in initial VAS score, SPADI, and NHP values between group H and group P (p > 0.05). Compared to the values of PRT, PST, and PST at months 1, 3, and 6, VAS, SPADI, and NHP values were statistically significantly lower in both groups (p shoulder pain. PBMT seems to be advantageous compared to SSN-pulsed RF therapy, as it is a noninvasive method.

  8. Long-lasting changes in brain activation induced by a single REAC technology pulse in Wi-Fi bands. Randomized double-blind fMRI qualitative study.

    Science.gov (United States)

    Rinaldi, Salvatore; Mura, Marco; Castagna, Alessandro; Fontani, Vania

    2014-07-11

    The aim of this randomized double-blind study was to evaluate in healthy adult subjects, with functional magnetic resonance imaging (fMRI), long lasting changes in brain activation patterns following administration of a single, 250 milliseconds pulse emitted with radio-electric asymmetric conveyer (REAC) technology in the Wi-Fi bands. The REAC impulse was not administered during the scan, but after this, according to a protocol that has previously been demonstrated to be effective in improving motor control and postural balance, in healthy subjects and patients. The study was conducted on 33 healthy volunteers, performed with a 1.5 T unit while operating a motor block task involving cyclical and alternating flexion and extension of one leg. Subsequently subjects were randomly divided into a treatment and a sham treatment control group. Repeated fMRI examinations were performed following the administration of the REAC pulse or sham treatment. The Treated group showed cerebellar and ponto-mesencephalic activation components that disappeared in the second scan, while these activation components persisted in the Sham group. This study shows that a very weak signal, such as 250 milliseconds Wi-Fi pulse, administered with REAC technology, could lead to lasting effects on brain activity modification.

  9. Phase delaying the human circadian clock with a single light pulse and moderate delay of the sleep/dark episode: no influence of iris color.

    Science.gov (United States)

    Canton, Jillian L; Smith, Mark R; Choi, Ho-Sun; Eastman, Charmane I

    2009-07-17

    Light exposure in the late evening and nighttime and a delay of the sleep/dark episode can phase delay the circadian clock. This study assessed the size of the phase delay produced by a single light pulse combined with a moderate delay of the sleep/dark episode for one day. Because iris color or race has been reported to influence light-induced melatonin suppression, and we have recently reported racial differences in free-running circadian period and circadian phase shifting in response to light pulses, we also tested for differences in the magnitude of the phase delay in subjects with blue and brown irises. Subjects (blue-eyed n = 7; brown eyed n = 6) maintained a regular sleep schedule for 1 week before coming to the laboratory for a baseline phase assessment, during which saliva was collected every 30 minutes to determine the time of the dim light melatonin onset (DLMO). Immediately following the baseline phase assessment, which ended 2 hours after baseline bedtime, subjects received a 2-hour bright light pulse (~4,000 lux). An 8-hour sleep episode followed the light pulse (i.e. was delayed 4 hours from baseline). A final phase assessment was conducted the subsequent night to determine the phase shift of the DLMO from the baseline to final phase assessment.Phase delays of the DLMO were compared in subjects with blue and brown irises. Iris color was also quantified from photographs using the three dimensions of red-green-blue color axes, as well as a lightness scale. These variables were correlated with phase shift of the DLMO, with the hypothesis that subjects with lighter irises would have larger phase delays. The average phase delay of the DLMO was -1.3 +/- 0.6 h, with a maximum delay of ~2 hours, and was similar for subjects with blue and brown irises. There were no significant correlations between any of the iris color variables and the magnitude of the phase delay. A single 2-hour bright light pulse combined with a moderate delay of the sleep/dark episode

  10. Phase delaying the human circadian clock with a single light pulse and moderate delay of the sleep/dark episode: no influence of iris color

    Directory of Open Access Journals (Sweden)

    Choi Ho-Sun

    2009-07-01

    Full Text Available Abstract Background Light exposure in the late evening and nighttime and a delay of the sleep/dark episode can phase delay the circadian clock. This study assessed the size of the phase delay produced by a single light pulse combined with a moderate delay of the sleep/dark episode for one day. Because iris color or race has been reported to influence light-induced melatonin suppression, and we have recently reported racial differences in free-running circadian period and circadian phase shifting in response to light pulses, we also tested for differences in the magnitude of the phase delay in subjects with blue and brown irises. Methods Subjects (blue-eyed n = 7; brown eyed n = 6 maintained a regular sleep schedule for 1 week before coming to the laboratory for a baseline phase assessment, during which saliva was collected every 30 minutes to determine the time of the dim light melatonin onset (DLMO. Immediately following the baseline phase assessment, which ended 2 hours after baseline bedtime, subjects received a 2-hour bright light pulse (~4,000 lux. An 8-hour sleep episode followed the light pulse (i.e. was delayed 4 hours from baseline. A final phase assessment was conducted the subsequent night to determine the phase shift of the DLMO from the baseline to final phase assessment. Phase delays of the DLMO were compared in subjects with blue and brown irises. Iris color was also quantified from photographs using the three dimensions of red-green-blue color axes, as well as a lightness scale. These variables were correlated with phase shift of the DLMO, with the hypothesis that subjects with lighter irises would have larger phase delays. Results The average phase delay of the DLMO was -1.3 ± 0.6 h, with a maximum delay of ~2 hours, and was similar for subjects with blue and brown irises. There were no significant correlations between any of the iris color variables and the magnitude of the phase delay. Conclusion A single 2-hour bright light

  11. Investigation of visible emission induced by infrared femtosecond pulses in erbium-doped YVO{sub 4} and LuVO{sub 4} single crystals

    Energy Technology Data Exchange (ETDEWEB)

    Ryba-Romanowski, Witold; Macalik, Bogusław; Strzęp, Adam; Lisiecki, Radosław, E-mail: R.Lisiecki@int.pan.wroc.pl; Solarz, Piotr; Kowalski, Robert M.

    2013-12-15

    Illumination of single crystal samples of erbium-doped YVO{sub 4} and LuVO{sub 4} by infrared femtosecond pulses brings about an intense green luminescence assigned to the {sup 4}S{sub 3/2} - {sup 4}I{sub 15/2} transition of Er{sup 3+} ions. When lowering the sample temperature an additional broad band in the blue related to the VO{sub 4}{sup 3−} emission appears and next grows steadily. It has been observed that the variation of wavelength of incident infrared femtosecond pulses in the region 800 nm–1600 nm affects weakly the intensity of both the blue and green luminescence bands. Analysis of luminescence dynamics made it possible to reveal that upon infrared excitation the rise time of the {sup 4}S{sub 3/2} luminescence is longer by a factor of four, roughly as compared to that recorded upon direct excitation into high energy levels of Er{sup 3+}. Observed temperature dependence of up-converted blue and green luminescence implies that the energy transfer from vanadate groups cannot be considered as a main mechanism involved in the excitation erbium ions. It has been supposed that erbium ions are likely to be excited by energy transfer from free electrons created in the conduction band of the host by multiphoton excitation and /or by non-resonant multi-step ETU process involving absorption of infrared light in multiphonon side bands of electronic transitions. Creation of free electrons has been corroborated by changes of electrical conductivity of crystals induced by an illumination with infrared femtosecond pulses. -- Highlights: • Processes of interaction of ultrashort light pulses with pure and rare earth-doped vanadate crystals are considered. • Effect and mechanism of excitation of up-converted visible luminescence initiated by infrared femtosecond pulses are examined. • The unlike phenomena was observed in relation to excitation with nanosecond or longer lasting light pulses. • The energy transfer from free electrons to erbium ions is concluded.

  12. A comparative study of the laser induce breakdown spectroscopy in single- and double-pulse laser geometry

    International Nuclear Information System (INIS)

    Sun Duixiong; Su Maogen; Dong Chenzhong; Wen Guanhong; Cao Xiangnian

    2013-01-01

    A time resolved laser induced breakdown spectroscopy technique (LIBS) was used for the investigation of emission signal enhancement on double-pulse LIBS. Two Q-switched Nd:YAG lasers at 1064 nm wavelength have been employed to generate laser-induced plasma on aluminium-based alloys. The plasma emission signals were recorded by spectrometer with ICCD detector. Spectral response calibration was performed by using deuterium and tungsten halogen lamps. Time evolution of the plasma temperature and electron density was investigated in SP and DP experiments. Based on the investigation of plasma parameters, the enhancements of emission line intensities were investigated, and the mechanisms of it were discussed. (author)

  13. Single-pass waveguide amplifiers in Er-Yb doped zinc polyphosphate glass fabricated with femtosecond laser pulses.

    Science.gov (United States)

    Fletcher, Luke B; Witcher, Jon J; Troy, Neil; Brow, Richard K; Krol, Denise M

    2012-04-01

    We have investigated the direct fabrication of subsurface waveguide amplifiers in Er-Yb zinc polyphosphate glass by utilizing the relationship between the initial glass composition and the resulting changes to the network structure after modification by fs laser pulses. Waveguides, exhibiting internal gain of 1 dB/cm at 1.53 μm when pumped with 500 mW at 976 nm, were directly fabricated using a regenerative amplified Ti:sapphire 1 kHz, 180 fs laser system. Optical properties as well as insertion losses and internal gain are reported.

  14. Status of the PuMa-ECR (Pulsed Magnetic field)

    International Nuclear Information System (INIS)

    Ratzinger, U.; Muehle, C.; Bleuel, W.; Joest, G.; Leible, K.; Schennach, S.; Wolf, B.H.

    1993-01-01

    Synchrotrons like the heavy ion synchrotron SIS at GSI need an efficient low duty cycle injector (typical 1 pulse/s and 200 μs pulse length). To improve the peak current, an ECR ion source has been designed using a pulsed magnetic field to force ion extraction. We replaced the hexapole of a 10 GHz MINIMAFIOS ECR ion source by a vacuum chamber containing a watercooled bilayered solenoid coil and a decapole permanent magnetic structure. A pulse line feeds the solenoid with a 250 μs pulse which increases the magnetic field in the minimum B region by 0.3 Tesla. This process opens the magnetic bottle along the beam axis resulting in an extracted ion pulse. First tests of the PuMa-ECR configuration in cw and pulsed operation are presented and analysed. (orig.)

  15. Cortico-cortical and motor evoked potentials to single and paired-pulse stimuli: An exploratory transcranial magnetic and intracranial electric brain stimulation study.

    Science.gov (United States)

    Boulogne, Sébastien; Andre-Obadia, Nathalie; Kimiskidis, Vasilios K; Ryvlin, Philippe; Rheims, Sylvain

    2016-11-01

    Paired-pulse (PP) paradigms are commonly employed to assess in vivo cortical excitability using transcranial magnetic stimulation (TMS) to stimulate the primary motor cortex and modulate the induced motor evoked potential (MEP). Single-pulse cortical direct electrical stimulation (DES) during intracerebral EEG monitoring allows the investigation of brain connectivity by eliciting cortico-cortical evoked potentials (CCEPs). However, PP paradigm using intracerebral DES has rarely been reported and has never been previously compared with TMS. The work was intended (i) to verify that the well-established modulations of MEPs following PP TMS remain similar using DES in the motor cortex, and (ii) to evaluate if a similar pattern could be observed in distant cortico-cortical connections through modulations of CCEP. Three patients undergoing intracerebral EEG monitoring with electrodes implanted in the central region were studied. Single-pulse DES (1-3 mA, 1 ms, 0.2 Hz) and PP DES using six interstimulus intervals (5, 15, 30, 50, 100, and 200 ms) in the motor cortex with concomitant recording of CCEPs and MEPs in contralateral muscles were performed. Finally, a navigated PP TMS session targeted the intracranial stimulation site to record TMS-induced MEPs in two patients. MEP modulations elicited by PP intracerebral DES proved similar among the three patients and to those obtained by PP TMS. CCEP modulations elicited by PP intracerebral DES usually showed a pattern comparable to that of MEP, although a different pattern could be observed occasionally. PP intracerebral DES seems to involve excitatory and inhibitory mechanisms similar to PP TMS and allows the recording of intracortical inhibition and facilitation modulation on cortico-cortical connections. Hum Brain Mapp 37:3767-3778, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  16. Characterisation of the UFXC32k hybrid pixel detector for time-resolved pump-probe diffraction experiments at Synchrotron SOLEIL

    Science.gov (United States)

    Dawiec, A.; Maj, P.; Ciavardini, A.; Gryboś, P.; Laulhé, C.; Menneglier, C.; Szczygieł, R.

    2017-03-01

    The experimental set-up for time-resolved studies of ultra-fast photo-induced structural dynamics at the Synchrotron SOLEIL is based on a general pump-probe scheme that has been developed and implemented on the CRISTAL hard X-ray diffraction beamline [1,2]. In a so-called pump-probe cycle, the sample is excited with an ultra-short laser pulse of ≈40 fs duration (the pump), and induced changes in its atomic structure are studied by measuring, with a precisely controlled delay, a diffraction pattern from a single pulse of synchrotron radiation (the probe) with a 2-D pixel detector. An improvement to the classical scheme is proposed, where the sample's response is probed at two different delays after each laser excitation. The first measurement at short delays allows studying the photo-induced dynamics. The second one is a reference measurement taken after sample's relaxation, which permits detection of drifts in the experimental conditions (e.g. beam misalignment, sample degradation). A hybrid pixel detector with a very fast readout time, a high dynamic range and extended linearity was tested to achieve the experiment objectives. In this paper, the first results obtained with the UFXC32k single photon counting detector are presented.

  17. Spin echo in synchrotrons

    Directory of Open Access Journals (Sweden)

    Alexander W. Chao

    2007-01-01

    Full Text Available As a polarized beam is accelerated through a depolarization resonance, its polarization is reduced by a well-defined calculable reduction factor. When the beam subsequently crosses a second resonance, the final beam polarization is considered to be reduced by the product of the two reduction factors corresponding to the two crossings, each calculated independently of the other. This is a good approximation when the spread of spin precession frequency Δν_{spin} of the beam (particularly due to its energy spread is sufficiently large that the spin precession phases of individual particles smear out completely during the time τ between the two crossings. This approximate picture, however, ignores two spin dynamics effects: an interference-overlap effect and a spin echo effect. This paper is to address these two effects. The interference-overlap effect occurs when Δν_{spin} is too small, or when τ is too short, to complete the smearing process. In this case, the two resonance crossings overlap each other, and the final polarization exhibits constructive or destructive interference patterns depending on the exact value of τ. Typically, the beam’s energy spread is large and this interference-overlap effect does not occur. To study this effect, therefore, it is necessary to reduce the beam energy spread and to consider two resonance crossings very close to each other. The other mechanism, also due to the interplay between two resonance crossings, is spin echo. It turns out that even when the precession phases appear to be completely smeared between the two crossings, there will still be a sudden and short-lived echo signal of beam polarization at a time τ after the second crossing; the magnitude of which can be as large as 57%. This echo signal exists even when the beam has a sizable energy spread and when τ is very large, and could be a sensitive (albeit challenging way to experimentally test the intricate spin dynamics in a synchrotron

  18. Contact microscopy with synchrotron radiation

    Energy Technology Data Exchange (ETDEWEB)

    Panessa-Warren, B.J.

    1985-10-01

    Soft x-ray contact microscopy with synchrotron radiation offers the biologist and especially the microscopist, a way to morphologically study specimens that could not be imaged by conventional TEM, STEM or SEM methods (i.e. hydrated samples, samples easily damaged by an electron beam, electron dense samples, thick specimens, unstained low contrast specimens) at spatial resolutions approaching those of the TEM, with the additional possibility to obtain compositional (elemental) information about the sample as well. Although flash x-ray sources offer faster exposure times, synchrotron radiation provides a highly collimated, intense radiation that can be tuned to select specific discrete ranges of x-ray wavelengths or specific individual wavelengths which optimize imaging or microanalysis of a specific sample. This paper presents an overview of the applications of x-ray contact microscopy to biological research and some current research results using monochromatic synchrotron radiation to image biological samples. 24 refs., 10 figs.

  19. The Cryogenic Anti-Coincidence detector for ATHENA X-IFU: pulse analysis of the AC-S7 single pixel prototype

    Science.gov (United States)

    D'Andrea, M.; Argan, A.; Lotti, S.; Macculi, C.; Piro, L.; Biasotti, M.; Corsini, D.; Gatti, F.; Torrioli, G.

    2016-07-01

    The ATHENA observatory is the second large-class mission in ESA Cosmic Vision 2015-2025, with a launch foreseen in 2028 towards the L2 orbit. The mission addresses the science theme "The Hot and Energetic Universe", by coupling a high-performance X-ray Telescope with two complementary focal-plane instruments. One of these is the X-ray Integral Field Unit (X-IFU): it is a TES based kilo-pixel order array able to provide spatially resolved high-resolution spectroscopy (2.5 eV at 6 keV) over a 5 arcmin FoV. The X-IFU sensitivity is degraded by the particles background expected at L2 orbit, which is induced by primary protons of both galactic and solar origin, and mostly by secondary electrons. To reduce the background level and enable the mission science goals, a Cryogenic Anticoincidence (CryoAC) detector is placed TESes. The CryoAC development schedule foresees by Q1 2017 the delivery of a Demonstration Model (DM) to the X-IFU FPA development team. The DM is a single-pixel detector that will address the final design of the CryoAC. It will verify some representative requirements at single-pixel level, especially the detector operation at 50 mK thermal bath and the threshold energy at 20 keV. To reach the final DM design we have developed and tested the AC-S7 prototype, with 1 cm2 absorber area sensed by 65 Ir TESes. Here we will discuss the pulse analysis of this detector, which has been illuminated by the 60 keV line from a 241Am source. First, we will present the analysis performed to investigate pulses timings and spectrum, and to disentangle the athermal component of the pulses from the thermal one. Furthermore, we will show the application to our dataset of an alternative method of pulse processing, based upon Principal Component Analysis (PCA). This kind of analysis allow us to recover better energy spectra than achievable with traditional methods, improving the evaluation of the detector threshold energy, a fundamental parameter characterizing the Cryo

  20. Nanodiamond embedded ta-C composite film by pulsed filtered vacuum arc deposition from a single target

    Science.gov (United States)

    Iyer, Ajai; Etula, Jarkko; Ge, Yanling; Liu, Xuwen; Koskinen, Jari

    2016-11-01

    Detonation Nanodiamonds (DNDs) are known to have sp3 core, sp2 shell, small size (few nm) and are gaining importance as multi-functional nanoparticles. Diverse methods have been used to form composites, containing detonation nanodiamonds (DNDs) embedded in conductive and dielectric matrices for various applications. Here we show a method, wherein DND-ta-C composite film, consisting of DNDs embedded in ta-C matrix have been co-deposited from the same cathode by pulsed filtered cathodic vacuum arc method. Transmission Electron Microscope analysis of these films revel the presence of DNDs embedded in the matrix of amorphous carbon. Raman spectroscopy indicates that the presence of DNDs does not adversely affect the sp3 content of DND-ta-C composite film compared to ta-C film of same thickness. Nanoindentation and nanowear tests indicate that DND-ta-C composite films possess improved mechanical properties in comparison to ta-C films of similar thickness.

  1. An efficient fluorescent single-particle position tracking system for long-term pulsed measurements of nitrogen-vacancy centers in diamond

    Science.gov (United States)

    Kim, Kiho; Yun, Jiwon; Lee, Donghyuck; Kim, Dohun

    2018-02-01

    A simple and convenient design enables real-time three-dimensional position tracking of nitrogen-vacancy (NV) centers in diamond. The system consists entirely of commercially available components (a single-photon counter, a high-speed digital-to-analog converter, a phase-sensitive detector-based feedback device, and a piezo stage), eliminating the need for custom programming or rigorous optimization processes. With a large input range of counters and trackers combined with high sensitivity of single-photon counting, high-speed position tracking (upper bound recovery time of 0.9 s upon 250 nm of step-like positional shift) not only of bright ensembles, but also of low-photon-collection-efficiency single to few NV centers (down to 103 s-1) is possible. The tracking requires position modulation of only 10 nm, which allows simultaneous position tracking and pulsed measurements in the long term. Therefore, this tracking system enables measuring a single-spin magnetic resonance and Rabi oscillations at a very high resolution even without photon collection optimization. The system is widely applicable to various fields related to NV center quantum manipulation research such as NV optical trapping, NV tracking in fluid dynamics, and biological sensing using NV centers inside a biological cell.

  2. Synchrotron radiation and structural proteomics

    CERN Document Server

    Pechkova, Eugenia

    2011-01-01

    This book presents an overview of the current state of research in both synchrotron radiation and structural proteomics from different laboratories worldwide. The book presents recent research results in the most advanced methods of synchrotron radiation analysis, protein micro- and nano crystallography, X-ray scattering and X-ray optics, coherent X-Ray diffraction, and laser cutting and contactless sample manipulation are described in details. The book focuses on biological applications and highlights important aspects such as radiation damage and molecular modeling.

  3. Light field driven streak-camera for single-shot measurements of the temporal profile of XUV-pulses from a free-electron laser; Lichtfeld getriebene Streak-Kamera zur Einzelschuss Zeitstrukturmessung der XUV-Pulse eines Freie-Elektronen Lasers

    Energy Technology Data Exchange (ETDEWEB)

    Fruehling, Ulrike

    2009-10-15

    The Free Electron Laser in Hamburg (FLASH) is a source for highly intense ultra short extreme ultraviolet (XUV) light pulses with pulse durations of a few femtoseconds. Due to the stochastic nature of the light generation scheme based on self amplified spontaneous emission (SASE), the duration and temporal profile of the XUV pulses fluctuate from shot to shot. In this thesis, a THz-field driven streak-camera capable of single pulse measurements of the XUV pulse-profile has been realized. In a first XUV-THz pump-probe experiment at FLASH, the XUV-pulses are overlapped in a gas target with synchronized THz-pulses generated by a new THz-undulator. The electromagnetic field of the THz light accelerates photoelectrons produced by the XUV-pulses with the resulting change of the photoelectron momenta depending on the phase of the THz field at the time of ionisation. This technique is intensively used in attosecond metrology where near infrared streaking fields are employed for the temporal characterisation of attosecond XUV-Pulses. Here, it is adapted for the analysis of pulse durations in the few femtosecond range by choosing a hundred times longer far infrared streaking wavelengths. Thus, the gap between conventional streak cameras with typical resolutions of hundreds of femtoseconds and techniques with attosecond resolution is filled. Using the THz-streak camera, the time dependent electric field of the THz-pulses was sampled in great detail while on the other hand the duration and even details of the time structure of the XUV-pulses were characterized. (orig.)

  4. X-ray fluorescence with synchrotron radiation

    International Nuclear Information System (INIS)

    Raman, S.; Sparks, C.J. Jr.

    1978-01-01

    An experimental set-up for x-ray fluorescence analysis with synchrotron radiation was built and installed at the Stanford Synchrotron Radiation Project. X-ray spectra were taken from numerous and varied samples in order to assess the potential of synchrotron radiation as an excitation source for multielement x-ray fluorescence analysis. For many applications, the synchrotron radiation technique is shown to be superior to other x-ray fluorescence methods, especially those employing electrons and protons as excitation sources

  5. Detection of explosives and other illicit materials by a single nanosecond neutron pulses - Monte-Carlo simulations of the detection process

    International Nuclear Information System (INIS)

    Miklaszewski, R.; Drozdowicz, K.; Wiacek, U.; Dworak, D.; Gribkov, V.

    2011-01-01

    Recent progress in the development of a single-pulse Nanosecond Impulse Neutron Investigation System (NINIS) intended for interrogation of hidden objects (explosives and other illicit materials) by means of measuring elastically scattered neutrons is presented in this paper. The method is based on the well know fact that nuclide-specific information is present in the scattered neutron field. The method uses very bright neutron pulses having duration of the order of few nanoseconds, generated by a dense plasma focus (DPF) devices filled with a pure deuterium or deuterium-tritium mixture as a working gas. Very short duration of the neutron pulse, its high brightness and mono-chromaticity allow to use the time-of-flight method with bases of about few meters to distinguish signals from neutrons scattered by different elements. Results of the Monte Carlo simulations of the scattered neutron field from several compounds (explosives and everyday use materials) are presented in the paper. The MCNP5 code has been used to get information on the angular and energy distributions of the neutrons scattered by the above mentioned compounds assuming the initial neutron energy equal to 2.45 MeV (D-D). A new input has been elaborated that allows the modelling of not only a spectrum of the neutrons scattered at different angles but also their time history from the moment of generation up to detection. Such an approach allows getting approximate signals as registered by scintillator + photomultiplier probes placed at various distances from the scattering object, demonstrating a principal capability of the method to identify an elemental content of the inspected objects. Preliminary results of the MCNP modelling of the interrogation process of the airport luggage containing several illicit objects are presented as well. (authors)

  6. Efficiency of Synchrotron Radiation from Rotation-powered Pulsars

    Energy Technology Data Exchange (ETDEWEB)

    Kisaka, Shota [Department of Physics and Mathematics, Aoyama Gakuin University, Sagamihara, Kanagawa, 252-5258 (Japan); Tanaka, Shuta J., E-mail: kisaka@phys.aoyama.ac.jp, E-mail: sjtanaka@center.konan-u.ac.jp [Department of Physics, Konan University, Kobe, Hyogo, 658-8501 (Japan)

    2017-03-01

    Synchrotron radiation is widely considered to be the origin of the pulsed non-thermal emissions from rotation-powered pulsars in optical and X-ray bands. In this paper, we study the synchrotron radiation emitted by the created electron and positron pairs in the pulsar magnetosphere to constrain the energy conversion efficiency from the Poynting flux to the particle energy flux. We model two pair creation processes, two-photon collision, which efficiently works in young γ -ray pulsars (≲10{sup 6} year), and magnetic pair creation, which is the dominant process to supply pairs in old pulsars (≳10{sup 6} year). Using the analytical model, we derive the maximum synchrotron luminosity as a function of the energy conversion efficiency. From the comparison with observations, we find that the energy conversion efficiency to the accelerated particles should be an order of unity in the magnetosphere, even though we make a number of the optimistic assumptions to enlarge the synchrotron luminosity. In order to explain the luminosity of the non-thermal X-ray/optical emission from pulsars with low spin-down luminosity L {sub sd} ≲ 10{sup 34} erg s{sup −1}, non-dipole magnetic field components should be dominant at the emission region. For the γ -ray pulsars with L {sub sd} ≲ 10{sup 35} erg s{sup −1}, observed γ -ray to X-ray and optical flux ratios are much higher than the flux ratio between curvature and the synchrotron radiations. We discuss some possibilities such as the coexistence of multiple accelerators in the magnetosphere as suggested from the recent numerical simulation results. The obtained maximum luminosity would be useful to select observational targets in X-ray and optical bands.

  7. Excitation of nuclear states by synchrotron radiation

    International Nuclear Information System (INIS)

    Olariu, Albert

    2003-01-01

    We study the excitation of nuclear states by gamma ray beams of energy up to 200 keV produced as synchrotron radiation. We consider the possibility to populate an excited state |i> in two steps, from the ground state |g> to an intermediary state |n> which decays by gamma emission or internal conversion to a lower state |i>. The aim of this study is to establish that the probability P 2 of the two-step transition |g> → |n> → |i> should be greater than the probability P 1 of the direct transition |g> → |i>. The probabilities P 1 and P 2 correspond to a radiation pulse of duration equal to the half-time of the state |i>. We have written a computer program in C++ which computes the probability P 2 , the ratio P 2 /P 1 and the rate C 2 of the two-step transitions for any nuclei and different configurations of states. The program uses a database which contains information on the energy levels, half-lives, spins and parities of nuclear states and on the relative intensities of the nuclear transitions. If the half-lives or the relative intensities are not known the program uses the Weisskopf estimates for the transition half-lives. An interpolation program of internal conversion coefficients has also been used. We listed the values obtained for P 2 , P 2 /P 1 and C 2 in a number of cases in which P 2 is significant from the 2900 considered cases. The states |i> and |n> have the energies E i and E n , the corresponding half-lives being t i and t n . The spectral density of the synchrotron radiation has been considered to be 10 12 photons cm -2 s -1 eV -1 . We listed only the cases for which the relative intensities of the transitions from levels |n> and |i> to lower states are known. The calculations carried out in this study allowed us to identify nuclei for which P 2 has relatively great values. In the listed cases P 2 /P 1 >>1, so that the two-step excitation by synchrotron radiation is more efficient than the direct excitation |g> → |i>. For a sample having 10

  8. Pulsed laser deposition of chalcogenide sulfides from multi- and single-component targets: the non-stoichiometric material transfer

    DEFF Research Database (Denmark)

    Schou, Jørgen; Ganskukh, Mungunshagai; Ettlinger, Rebecca Bolt

    2018-01-01

    , and the Cu content is also very low at low fluence from a single-component target. Above this threshold, the Cu content in the films increases almost linearly up to a value above the stoichiometric value, while the ratio of the concentration of the other metals Zn to Sn (Zn/Sn) remains constant. Films...

  9. Single particle deformation and analysis of the same silica coated gold nanorods before and after fs-laser pulse excitation

    NARCIS (Netherlands)

    Albrecht, W.; Deng, Tian-Song; Goris, Bart; van Huis, M.A.; Bals, Sarah; van Blaaderen, Alfons

    2016-01-01

    We performed single particle deformation experiments on silicacoated gold nanorods under femtosecond (fs) illumination. Changes in the particle shape were analyzed by electron microscopy and associated changes in the plasmon resonance by electron energy loss spectroscopy. Silica-coated rods were

  10. High-pressure single-crystal neutron diffraction (to 20 kbar) using a pulsed source: Preliminary investigation of Tl3PSe4

    International Nuclear Information System (INIS)

    Alkire, R.W.; Larson, A.C.; Vergamini, P.J.; Schirber, J.E.; Morosin, B.

    1985-01-01

    A new technique is described for performing high-pressure single-crystal neutron diffraction [up to 20 kbar (2GPa) at room temperature], using a BeCu pressure cell, an area detector and the Los Alamos National Laboratory pulsed neutron source. Success of this method depends on the increase in information available with a multi-wavelength pulse neutron source, a novel orientation of a cylindrically symmetric pressure cell with its axis coincident with the neutron beam and a specific crystal orientation within the pressure cell. Bragg scattering from the pressure cell is avoided and background for a given 2theta is constant. For a crystal of orthorhombic or higher symmetry oriented with the incident beam passing midway between the major lattice vectors, it will be possible to refine a complete three-dimensional structure with data collected from only one pressure loading. Preliminary investigations of Tl 3 PSe 4 lattice parameters (space group Pcmn) at 15(1)kbar yielded linear compressibilities (. 1000 in kbar -1 ) of Ksub(a) = 1.05(8), Ksub(b) = 1.50(10), Ksub(c) = 1.20(8). The anisotropic compressibility is explained by examination of the ambient-pressure room-temperature structure. (orig.)

  11. DESY: Synchrotron and storage rings

    CERN Multimedia

    1972-01-01

    An improvement programme has been under way for several years at the 7.5 GeV électron synchrotron at DESY. In particular it has been designed to increase the accelerated beam intensity, to achieve better quality of the ejected électron beams and photon beams and to improve machine reliability.

  12. Biological physics and synchrotron radiation

    Energy Technology Data Exchange (ETDEWEB)

    Filhol, J.M.; Chavanne, J. [European Synchrotron Radiation Facility, 38 - Grenoble (France); Weckert, E. [Hasylab at Desy, Hamburg (Germany)] [and others

    2001-07-01

    This conference deals with the applications of synchrotron radiation to current problems in biology and medicine. Seven sessions take stock on the subject: sources and detectors; inelastic scattering and dynamics; muscle diffraction; reaction mechanisms; macromolecular assemblies; medical applications; imaging and spectroscopy. The document presents the papers abstracts. (A.L.B.)

  13. The Australian synchrotron research program

    International Nuclear Information System (INIS)

    Garrett, R.F.

    1998-01-01

    Full text: The Australian Synchrotron Research Program (ASRP) was established in 1996 under a 5 year grant from the Australian Government, and is managed by ANSTO on behalf of a consortium of Australian universities and research organisations. It has taken over the operation of the Australian National Beamline Facility (ANBF) at the Photon Factory, and has joined two CATS at the Advanced Photon Source: the Synchrotron Radiation Instrumentation CAT (SRI-CAT) and the Consortium for Advanced Radiation Sources (CARS). The ASRP thus manages a comprehensive range of synchrotron radiation research facilities for Australian science. The ANBF is a general purpose hard X-ray beamline which has been in operation at the Photon Factory since 1993. It currently caters for about 35 Australian research teams per year. The facilities available at the ANBF will be presented and the research program will be summarised. The ASRP facilities at the APS comprise the 5 sectors operated by SRI-CAT, BioCARS and ChemMatCARS. A brief description will be given of the ASRP research programs at the APS, which will considerably broaden the scope of Australian synchrotron science

  14. Optical systems for synchrotron radiation

    International Nuclear Information System (INIS)

    Howells, M.R.

    1985-12-01

    Various fundamental topics which underlie the design and use of optical systems for synchrotron radiation are considered from the viewpoint of linear system theory. These topics include the damped harmonic oscillator, free space propagation of an optical field, electromagnetic theory of optical properties of materials, theory of dispersion, and the Kramers-Kronig relations. 32 refs., 5 figs

  15. Biological physics and synchrotron radiation

    International Nuclear Information System (INIS)

    Filhol, J.M.; Chavanne, J.; Weckert, E.

    2001-01-01

    This conference deals with the applications of synchrotron radiation to current problems in biology and medicine. Seven sessions take stock on the subject: sources and detectors; inelastic scattering and dynamics; muscle diffraction; reaction mechanisms; macromolecular assemblies; medical applications; imaging and spectroscopy. The document presents the papers abstracts. (A.L.B.)

  16. Relaxation experiments with synchrotron radiation

    NARCIS (Netherlands)

    Leupold, O; Bernhard, A; Gerdau, E; Jaschke, J; Ruter, HD; Shvydko, Y; Alp, EE; Hession, P; Hu, M; Sturhahn, W; Sutter, J; Toellner, T; Chumakov, AI; Metge, J; Ruffer, R

    1998-01-01

    Relaxation phenomena show up in standard energy domain Mossbauer spectra via line broadening. The evaluation of such spectra is in most cases done by adopting the stochastic theory mainly developed in the 60s and 70s. Due to the time structure and the polarization of the synchrotron radiation

  17. Synchrotron radiation and biomedical imaging

    International Nuclear Information System (INIS)

    Luccio, A.

    1986-08-01

    In this lecture we describe the characteristics of Synchrotron radiation as a source of X rays. We discuss the properties of SR arc sources, wigglers, undulators and the use of backscattering of laser light. Applications to angiography, X ray microscopy and tomography are reviewed. 16 refs., 23 figs

  18. Single-electron multiplication statistics as a combination of Poissonian pulse height distributions using constraint regression methods

    International Nuclear Information System (INIS)

    Ballini, J.-P.; Cazes, P.; Turpin, P.-Y.

    1976-01-01

    Analysing the histogram of anode pulse amplitudes allows a discussion of the hypothesis that has been proposed to account for the statistical processes of secondary multiplication in a photomultiplier. In an earlier work, good agreement was obtained between experimental and reconstructed spectra, assuming a first dynode distribution including two Poisson distributions of distinct mean values. This first approximation led to a search for a method which could give the weights of several Poisson distributions of distinct mean values. Three methods have been briefly exposed: classical linear regression, constraint regression (d'Esopo's method), and regression on variables subject to error. The use of these methods gives an approach of the frequency function which represents the dispersion of the punctual mean gain around the whole first dynode mean gain value. Comparison between this function and the one employed in Polya distribution allows the statement that the latter is inadequate to describe the statistical process of secondary multiplication. Numerous spectra obtained with two kinds of photomultiplier working under different physical conditions have been analysed. Then two points are discussed: - Does the frequency function represent the dynode structure and the interdynode collection process. - Is the model (the multiplication process of all dynodes but the first one, is Poissonian) valid whatever the photomultiplier and the utilization conditions. (Auth.)

  19. Ultrafast photoisomerization and its single-shot pump pulse efficiency of trans-azobenzene derivative: Compound for photosensitive DNA

    Science.gov (United States)

    Chen, Tao; Yamaguchi, Atsushi; Igarashi, Kazumasa; Nakagawa, Naoya; Nishioka, Hidenori; Asanuma, Hiroyuki; Yamashita, Mikio

    2012-03-01

    The femtosecond photoisomerization processes of trans (T) 4-carboxy-2',6'-dimethylazobenzen, which has been employed recently as an efficient photoregulator of DNA hybridization, were clarified by the rate equation analysis of measured transient absorbance changes with (350 nm) and without (380 nm) ground-state absorption of both the reactant (T) and photoproduct ( cis: C) isomers under S 2T-band excitation (360 nm, 150 fs pump): after excitation to the S 2T state with a 450-fs lifetime, ~ 1.5% of the T-molecules in the S 2T state are isomerized to the C-form within ~ 6 ps through the intermediate state (so called bottleneck state), but most of those return back to the T ground-state S 2T via the internal conversion processes with an ultrafast kinetic rate of 2.2 × 10 12 s - 1 . Moreover, the rate equation analysis enables us to determine the T-to-C photoisomerization rate ηT,C per pump pulse to be 0.0011 at the pump energy of 80 nJ from the amplitude A3,350 of the offset component in the 350-nm probe signal, and to obtain the photoisomerization quantum yield Φ T,C = 0.094. The latter value is slightly lower than that of T-azobenzene, and well agrees with that (Φ T,C = 0.097) measured by the conventional CW irradiation method using a photostationary state.

  20. Ferroelectrics under the Synchrotron Light: A Review

    Directory of Open Access Journals (Sweden)

    Luis E. Fuentes-Cobas

    2015-12-01

    Full Text Available Currently, an intensive search for high-performance lead-free ferroelectric materials is taking place. ABO3 perovskites (A = Ba, Bi, Ca, K and Na; B = Fe, Nb, Ti, and Zr appear as promising candidates. Understanding the structure–function relationship is mandatory, and, in this field, the roles of long- and short-range crystal orders and interactions are decisive. In this review, recent advances in the global and local characterization of ferroelectric materials by synchrotron light diffraction, scattering and absorption are analyzed. Single- and poly-crystal synchrotron diffraction studies allow high-resolution investigations regarding the long-range average position of ions and subtle global symmetry break-downs. Ferroelectric materials, under the action of electric fields, undergo crystal symmetry, crystallite/domain orientation distribution and strain condition transformations. Methodological aspects of monitoring these processes are discussed. Two-dimensional diffraction clarify larger scale ordering: polycrystal texture is measured from the intensities distribution along the Debye rings. Local order is investigated by diffuse scattering (DS and X-ray absorption fine structure (XAFS experiments. DS provides information about thermal, chemical and displacive low-dimensional disorders. XAFS investigation of ferroelectrics reveals local B-cation off-centering and oxidation state. This technique has the advantage of being element-selective. Representative reports of the mentioned studies are described.

  1. Ferroelectrics under the Synchrotron Light: A Review

    Science.gov (United States)

    Fuentes-Cobas, Luis E.; Montero-Cabrera, María E.; Pardo, Lorena; Fuentes-Montero, Luis

    2015-01-01

    Currently, an intensive search for high-performance lead-free ferroelectric materials is taking place. ABO3 perovskites (A = Ba, Bi, Ca, K and Na; B = Fe, Nb, Ti, and Zr) appear as promising candidates. Understanding the structure–function relationship is mandatory, and, in this field, the roles of long- and short-range crystal orders and interactions are decisive. In this review, recent advances in the global and local characterization of ferroelectric materials by synchrotron light diffraction, scattering and absorption are analyzed. Single- and poly-crystal synchrotron diffraction studies allow high-resolution investigations regarding the long-range average position of ions and subtle global symmetry break-downs. Ferroelectric materials, under the action of electric fields, undergo crystal symmetry, crystallite/domain orientation distribution and strain condition transformations. Methodological aspects of monitoring these processes are discussed. Two-dimensional diffraction clarify larger scale ordering: polycrystal texture is measured from the intensities distribution along the Debye rings. Local order is investigated by diffuse scattering (DS) and X-ray absorption fine structure (XAFS) experiments. DS provides information about thermal, chemical and displacive low-dimensional disorders. XAFS investigation of ferroelectrics reveals local B-cation off-centering and oxidation state. This technique has the advantage of being element-selective. Representative reports of the mentioned studies are described. PMID:28787814

  2. Single-Step Fabrication of Gd2O3@SiO2 Nanoparticles for use as MRI Contrast Agents by Pulsed Laser Ablation in Liquid

    Science.gov (United States)

    Luo, Ning-Qi; Huang, Zhan-Yun; Li, Li; Shao, Yuan-Zhi; Chen, Di-Hu

    2013-03-01

    Gd2O3@SiO2 nanoparticles with a core-shell structure are synthesized by pulsed laser ablation in liquid (PLAL) in single steps. A Gd2O3 target immersed in tetraethyl orthosilicate (TEOS) is ablated by a microsecond Nd:YAG laser, which induces the generation of a Gd2O3 plasma plume and pyrolysis of the TEOS. We propose that the moment Gd2O3 nanoparticles are formed they will be coated immediately by SiO2 and directly synthesized Gd2O3@SiO2 core-shell nanoparticles. These particles obtain high r1 relaxivity of 5.26s-1mM-1 and are used as T1-weighted magnetic resonance imaging contrast agents. It is shown that the PLAL technique is promising for fabricating core-shell structure nanomaterial with potential medical applications.

  3. Pulsed irradiation improves target selectivity of infrared laser-evoked gene operator for single-cell gene induction in the nematode C. elegans.

    Science.gov (United States)

    Suzuki, Motoshi; Toyoda, Naoya; Takagi, Shin

    2014-01-01

    Methods for turning on/off gene expression at the experimenter's discretion would be useful for various biological studies. Recently, we reported on a novel microscope system utilizing an infrared laser-evoked gene operator (IR-LEGO) designed for inducing heat shock response efficiently in targeted single cells in living organisms without cell damage, thereby driving expression of a transgene under the control of a heat shock promoter. Although the original IR-LEGO can be successfully used for gene induction, several limitations hinder its wider application. Here, using the nematode Caenorhabditis elegans (C. elegans) as a subject, we have made improvements in IR-LEGO. For better spatial control of heating, a pulsed irradiation method using an optical chopper was introduced. As a result, single cells of C. elegans embryos as early as the 2-cell stage and single neurons in ganglia can be induced to express genes selectively. In addition, the introduction of site-specific recombination systems to IR-LEGO enables the induction of gene expression controlled by constitutive and cell type-specific promoters. The strategies adopted here will be useful for future applications of IR-LEGO to other organisms.

  4. Phase-locked MHz pulse selector for x-ray sources.

    Science.gov (United States)

    Förster, Daniel F; Lindenau, Bernd; Leyendecker, Marko; Janssen, Franz; Winkler, Carsten; Schumann, Frank O; Kirschner, Jürgen; Holldack, Karsten; Föhlisch, Alexander

    2015-05-15

    Picosecond x-ray pulses are extracted with a phase-locked x-ray pulse selector at 1.25 MHz repetition rate from the pulse trains of the accelerator-driven multiuser x-ray source BESSY II preserving the peak brilliance at high pulse purity. The system consists of a specially designed in-vacuum chopper wheel rotating with ≈1  kHz angular frequency. The wheel is driven in an ultrahigh vacuum and is levitated on magnetic bearings being capable of withstanding high centrifugal forces. Pulses are picked by 1252 high-precision slits of 70 μm width on the outer rim of the wheel corresponding to a temporal opening window of the chopper of 70 ns. We demonstrate how the electronic phase stabilization of ±2  ns together with an arrival time jitter of the individual slits of the same order of magnitude allows us to pick short single bunch x-ray pulses out of a 200 ns ion clearing gap in a multibunch pulse train as emitted from a synchrotron facility at 1.25 MHz repetition rate with a pulse purity below the shot noise detection limit. The approach is applicable to any high-repetition pulsed radiation source, in particular in the x-ray spectral range up to 10 keV. The opening window in a real x-ray beamline, its stability, as well as the limits of mechanical pulse picking techniques in the MHz range are discussed.

  5. High-current, low-energy synchrotrons and compressor rings

    International Nuclear Information System (INIS)

    Kustom, R.L.

    1984-01-01

    The primary application of high-current, low-energy synchrotrons and linac compressor rings is as proton drivers for pulsed-spallation neutron sources. They operate in the range of 500 to 1500 MeV with extracted beam repetition rates between 12 to 100 Hz. The time-averaged currents on target are a few tens of microamperes today, soon will be a few thousand in the future. The characteristics for the accelerators and compressor rings, their limitations, and existing and proposed major facilities are described. 22 references, 5 figures, 6 tables

  6. Development of a High Dynamic Range Pixel Array Detector for Synchrotrons and XFELs

    Science.gov (United States)

    Weiss, Joel Todd

    Advances in synchrotron radiation light source technology have opened new lines of inquiry in material science, biology, and everything in between. However, x-ray detector capabilities must advance in concert with light source technology to fully realize experimental possibilities. X-ray free electron lasers (XFELs) place particularly large demands on the capabilities of detectors, and developments towards diffraction-limited storage ring sources also necessitate detectors capable of measuring very high flux [1-3]. The detector described herein builds on the Mixed Mode Pixel Array Detector (MM-PAD) framework, developed previously by our group to perform high dynamic range imaging, and the Adaptive Gain Integrating Pixel Detector (AGIPD) developed for the European XFEL by a collaboration between Deustsches Elektronen-Synchrotron (DESY), the Paul-Scherrer-Institute (PSI), the University of Hamburg, and the University of Bonn, led by Heinz Graafsma [4, 5]. The feasibility of combining adaptive gain with charge removal techniques to increase dynamic range in XFEL experiments is assessed by simulating XFEL scatter with a pulsed infrared laser. The strategy is incorporated into pixel prototypes which are evaluated with direct current injection to simulate very high incident x-ray flux. A fully functional 16x16 pixel hybrid integrating x-ray detector featuring several different pixel architectures based on the prototypes was developed. This dissertation describes its operation and characterization. To extend dynamic range, charge is removed from the integration node of the front-end amplifier without interrupting integration. The number of times this process occurs is recorded by a digital counter in the pixel. The parameter limiting full well is thereby shifted from the size of an integration capacitor to the depth of a digital counter. The result is similar to that achieved by counting pixel array detectors, but the integrators presented here are designed to tolerate a

  7. CVD diamond windows for infrared synchrotron applications

    International Nuclear Information System (INIS)

    Sussmann, R.S.; Pickles, C.S.J.; Brandon, J.R.; Wort, C.J.H.; Coe, S.E.; Wasenczuk, A.; Dodge, C.N.; Beale, A.C.; Krehan, A.J.; Dore, P.; Nucara, A.; Calvani, P.

    1998-01-01

    This paper describes the attributes that make diamond a unique material for infrared synchrotron beam experiments. New developments in diamond synthesised by Chemical Vapour Deposition (CVD) promise to extend the range of applications which have been hitherto limited by the availability and cost of large-size single-crystal diamond. Polycrystalline CVD diamond components such as large (100 mm) diameter windows with extremely good transparency over a wide spectral range are now commercially available. Properties of CVD diamond of relevance to optical applications, such as mechanical strength, thermal conductivity and absolute bulk absorption, are discussed. It is shown that although some of the properties of CVD diamond (similar to other polycrystalline industrial ceramics) are affected by the grain structure, currently produced CVD diamond optical components have the quality and performance required for numerous demanding applications

  8. Synchrotron radiation in solid state chemistry

    International Nuclear Information System (INIS)

    Ghigna, Paolo; Pin, Sonia; Spinolo, Giorgio; Newton, Mark A.; Chiara Tarantino, Serena; Zema, Michele

    2011-01-01

    An approach towards the reactivity in the solid state is proposed, primarily based on recognizing the crucial role played by the interfacial free energy and by the topotactical relationship between the two reactants, which in turn control formation of the new phase and its spatial and orientational relationships with respect to the parent phases. Using one of the reactants in the form of film, the ratio between bulk and interfacial free energy can be changed, and the effect of interfacial free energy is maximized. The role of Synchrotron Radiation in such an approach is exemplified by using a new developed technique for μ-XANES mapping with nanometric resolution for studying the reactivity of thin films of NiO onto differently oriented Al 2 O 3 single crystals. The result obtained allowed us to speculate about the rate determining step of the NiO+Al 2 O 3 →NiAl 2 O 4 interfacial reaction.

  9. Advances in single- and multi-stage Stirling-type pulse tube cryocoolers for space applications in NLIP/SITP/CAS

    Science.gov (United States)

    Dang, Haizheng; Tan, Jun; Zha, Rui; Li, Jiaqi; Zhang, Lei; Zhao, Yibo; Gao, Zhiqian; Bao, Dingli; Li, Ning; Zhang, Tao; Zhao, Yongjiang; Zhao, Bangjian

    2017-12-01

    This paper presents a review of recent advances in single- and multi-stage Stirling-type pulse tube cryocoolers (SPTCs) for space applications developed at the National Laboratory for Infrared Physics, Shanghai Institute of Technical Physics, Chinese Academy of Sciences (NLIP/SITP/CAS). A variety of single-stage SPTCs operating at 25-150 K have been developed, including several mid-sized ones operating at 80-110 K. Significant progress has been achieved in coolers operating at 30-40 K which use common stainless steel meshes as regenerator matrices. Another important advance is the micro SPTCs with an overall mass of 300-800 g operating at high frequencies varying from 100 Hz to 400 Hz. The main purpose of developing two-stage SPTCs is to simultaneously acquire cooling capacities at both stages, obviating the need for auxiliary precooling in various applications. The three-stage SPTCs are developed mainly for applications at around 10 K, which are also used for precooling the J-T coolers to achieve further lower temperatures. The four-stage SPTCs are developed to directly achieve the liquid helium temperature for cooling space low-Tc superconducting devices and for the deep space exploration as well. Several typical development programs are described and an overview of the cooler performances is presented.

  10. Medical applications of synchrotron radiation

    International Nuclear Information System (INIS)

    Thomlinson, W.

    1991-10-01

    Ever since the first diagnostic x-ray was done in the United States on February 3, 1896, the application of ionizing radiation to the field of medicine has become increasingly important. Both in clinical medicine and basic research the use of x-rays for diagnostic imaging and radiotherapy is now widespread. Radiography, angiography, CAT and PETT scanning, mammography, and nuclear medicine are all examples of technologies developed to image the human anatomy. In therapeutic applications, both external and internal sources of radiation are applied to the battle against cancer. The development of dedicated synchrotron radiation sources has allowed exciting advances to take place in many of these applications. The new sources provide tunable, high-intensity monochromatic beams over a wide range of energies which can be tailored to specific programmatic needs. This paper surveys those areas of medical research in which synchrotron radiation facilities are actively involved

  11. Synchrotron radiation in atomic physics

    International Nuclear Information System (INIS)

    Crasemann, B.

    1998-01-01

    Much of present understanding of atomic and molecular structure and dynamics was gained through studies of photon-atom interactions. In particular, observations of the emission, absorption, and scattering of X rays have complemented particle-collision experiments in elucidating the physics of atomic inner shells. Grounded on Max von Laue's theoretical insight and the invention of the Bragg spectrometer, the field's potential underwent a step function with the development of synchrotron-radiation sources. Notably current third-generation sources have opened new horizons in atomic and molecular physics by producing radiation of wide tunability and exceedingly high intensity and polarization, narrow energy bandwidth, and sharp time structure. In this review, recent advances in synchrotron-radiation studies in atomic and molecular science are outlined. Some tempting opportunities are surveyed that arise for future studies of atomic processes, including many-body effects, aspects of fundamental photon-atom interactions, and relativistic and quantum-electrodynamic phenomena. (author)

  12. Medical Applications of Synchrotron Radiation

    Science.gov (United States)

    Thomlinson, W.

    1991-10-01

    Ever since the first diagnostic x-ray was done in the United States on February 3, 1896, the application of ionizing radiation to the field of medicine has become increasingly important. Both in clinical medicine and basic research the use of x-rays for diagnostic imaging and radiotherapy is now widespread. Radiography, angiography, CAT and PETT scanning, mammography, and nuclear medicine are all examples of technologies developed to image the human anatomy. In therapeutic applications, both external and internal sources of radiation are applied to the battle against cancer. The development of dedicated synchrotron radiation sources has allowed exciting advances to take place in many of these applications. The new sources provide tunable, high-intensity monochromatic beams over a wide range of energies which can be tailored to specific programmatic needs. This paper surveys those areas of medical research in which synchrotron radiation facilities are actively involved.

  13. Australian synchrotron light source - (boomerang)

    International Nuclear Information System (INIS)

    Boldeman, J.

    2001-01-01

    The Australian National Synchrotron Light Source - (Boomerang) is to be installed at the Monash University in Victoria. This report provides some background to the proposed facility and discusses aspects of a prospective design. Recently, significant effort was devoted to refining the in principle design and a lattice providing an emittance od 18 nm rad was obtained with a distributed dispersion in the straight section of 0.29m. Exhaustive studies have been made of the economic benefits that would accrue to Australia to Australia following the installation of this facility. This design is a refinement of the design concept presented to the SRI -2000, Berlin (Boldeman, Einfeld et al), to the meeting of the 4th Asian Forum and the Preliminary Design Study presented to the Australian Synchrotron Research Program

  14. An ion synchrotron design program

    International Nuclear Information System (INIS)

    Yoshida, Katsuhisa; Ishi, Yoshihiro

    1995-01-01

    Ion synchrotrons have promising applications in medical and other commercial settings as well as in physics research. Mitsubishi Electric has developed a program to facilitate efficiency studies on processes such as ion injection, radio-frequency capture and acceleration, and beam extraction. The integration method used in the particle-orbit calculations maintains the symplectic characteristic of Hamilton dynamics making it possible to simulate long-term phenomena reliably. The article introduces this program and several of its applications. (author)

  15. Synchrotron-based photoelectron microscopy

    International Nuclear Information System (INIS)

    Barinov, Alexei; Dudin, Pavel; Gregoratti, Luca; Locatelli, Andrea; Onur Mentes, Tevfik; Angel Nino, Miquel; Kiskinova, Maya

    2009-01-01

    The paper is a brief overview of the operation principles and the potentials of the scanning photoelectron microscopes (SPEM) and X-ray photoemission electron microscopes (XPEEM) operating at synchrotron facilities. Selected results will illustrate the impact of high spatial resolution for micro-characterization of the surface composition and electronic structure, a key issue for analysis of technologically relevant materials and for fundamental understanding of many unexplored surface phenomena.

  16. Threedimensional microfabrication using synchrotron radiation

    International Nuclear Information System (INIS)

    Ehrfeld, W.

    1990-01-01

    For fabricating microstructures with extreme structural heights a technology has been developed which is based on deep-etch lithography and subsequent replication processes. A particularly high precision is achieved if the lithographic process is carried out by means of synchrotron radiation. Electroforming and molding processes are used for the replication of microstructures from a large variety of materials. The field of application comprises sensors, electrical and optical microconnectors, components for fluid technology, microfiltration systems and novel composite materials. (author)

  17. Infrared microspectroscopy with synchrotron radiation

    Energy Technology Data Exchange (ETDEWEB)

    Carr, G.L.; Williams, G.P. [Brookhaven National Lab., Upton, NY (United States). National Synchrotron Light Source

    1997-09-01

    Infrared microspectroscopy with a high brightness synchrotron source can achieve a spatial resolution approaching the diffraction limit. However, in order to realize this intrinsic source brightness at the specimen location, some care must be taken in designing the optical system. Also, when operating in diffraction limited conditions, the effective spatial resolution is no longer controlled by the apertures typically used for a conventional (geometrically defined) measurement. Instead, the spatial resolution depends on the wavelength of light and the effective apertures of the microscope`s Schwarzchild objectives. The authors have modeled the optical system from the synchrotron source up to the sample location and determined the diffraction-limited spatial distribution of light. Effects due to the dependence of the synchrotron source`s numerical aperture on wavelength, as well as the difference between transmission and reflection measurement modes, are also addressed. Lastly, they examine the benefits (when using a high brightness source) of an extrinsic germanium photoconductive detector with cone optics as a replacement for the standard MCT detector.

  18. Synchrotron/crystal sample preparation

    Science.gov (United States)

    Johnson, R. Barry

    1993-01-01

    The Center for Applied Optics (CAO) of the University of Alabama in Huntsville (UAH) prepared this final report entitled 'Synchrotron/Crystal Sample Preparation' in completion of contract NAS8-38609, Delivery Order No. 53. Hughes Danbury Optical Systems (HDOS) is manufacturing the Advanced X-ray Astrophysics Facility (AXAF) mirrors. These thin-walled, grazing incidence, Wolter Type-1 mirrors, varying in diameter from 1.2 to 0.68 meters, must be ground and polished using state-of-the-art techniques in order to prevent undue stress due to damage or the presence of crystals and inclusions. The effect of crystals on the polishing and grinding process must also be understood. This involves coating special samples of Zerodur and measuring the reflectivity of the coatings in a synchrotron system. In order to gain the understanding needed on the effect of the Zerodur crystals by the grinding and polishing process, UAH prepared glass samples by cutting, grinding, etching, and polishing as required to meet specifications for witness bars for synchrotron measurements and for investigations of crystals embedded in Zerodur. UAH then characterized these samples for subsurface damage and surface roughness and figure.

  19. Rotating crystal cube as a variable shutter for use with synchrotron radiation

    International Nuclear Information System (INIS)

    McPherson, A.

    1998-01-01

    A beam chopper together with the temporal structure of x-rays emitted by a synchrotrons storage ring can be utilized to generate x-ray bursts of variable length and time separation. A Si cube, cut for diffraction from the (220) planes, was mounted to a low-speed motor to produce a beam chopper based upon the Darwin width of the crystal. An x-ray pulse, consisting of an envelope of individual pulses characterizing the loading pattern of the storage ring, was transmitted. The width of the transmitted pulse and the time between pulses was varied by varying the rotation frequency of the Si cube. Pulses as short as ∼75 ps or as long as ∼4 micros were transmitted with pulse separation spanning from 4 ms to 167 ms

  20. Initial scientific uses of coherent synchrotron radiation inelectron storage rings

    Energy Technology Data Exchange (ETDEWEB)

    Basov, D.N.; Feikes, J.; Fried, D.; Holldack, K.; Hubers, H.W.; Kuske, P.; Martin, M.C.; Pavlov, S.G.; Schade, U.; Singley, E.J.; Wustefeld, G.

    2004-11-23

    The production of stable, high power, coherent synchrotron radiation at sub-terahertz frequency at the electron storage ring BESSY opens a new region in the electromagnetic spectrum to explore physical properties of materials. Just as conventional synchrotron radiation has been a boon to x-ray science, coherent synchrotron radiation may lead to many new innovations and discoveries in THz physics. With this new accelerator-based radiation source we have been able to extend traditional infrared measurements down into the experimentally poorly accessible sub-THz frequency range. The feasibility of using the coherent synchrotron radiation in scientific applications was demonstrated in a series of experiments: We investigated shallow single acceptor transitions in stressed and unstressed Ge:Ga by means of photoconductance measurements below 1 THz. We have directly measured the Josephson plasma resonance in optimally doped Bi{sub 2}Sr{sub 2}CaCu{sub 2}O{sub 8} for the first time and finally we succeeded to confine the sub-THz radiation for spectral near-field imaging on biological samples such as leaves and human teeth.

  1. High-speed X-ray imaging pixel array detector for synchrotron bunch isolation

    International Nuclear Information System (INIS)

    Philipp, Hugh T.; Tate, Mark W.; Purohit, Prafull; Shanks, Katherine S.; Weiss, Joel T.; Gruner, Sol M.

    2016-01-01

    A high-speed pixel array detector for time-resolved X-ray imaging at synchrotrons has been developed. The ability to isolate single synchrotron bunches makes it ideal for time-resolved dynamical studies. A wide-dynamic-range imaging X-ray detector designed for recording successive frames at rates up to 10 MHz is described. X-ray imaging with frame rates of up to 6.5 MHz have been experimentally verified. The pixel design allows for up to 8–12 frames to be stored internally at high speed before readout, which occurs at a 1 kHz frame rate. An additional mode of operation allows the integration capacitors to be re-addressed repeatedly before readout which can enhance the signal-to-noise ratio of cyclical processes. This detector, along with modern storage ring sources which provide short (10–100 ps) and intense X-ray pulses at megahertz rates, opens new avenues for the study of rapid structural changes in materials. The detector consists of hybridized modules, each of which is comprised of a 500 µm-thick silicon X-ray sensor solder bump-bonded, pixel by pixel, to an application-specific integrated circuit. The format of each module is 128 × 128 pixels with a pixel pitch of 150 µm. In the prototype detector described here, the three-side buttable modules are tiled in a 3 × 2 array with a full format of 256 × 384 pixels. The characteristics, operation, testing and application of the detector are detailed

  2. Pulse Generator

    Science.gov (United States)

    Greer, Lawrence (Inventor)

    2017-01-01

    An apparatus and a computer-implemented method for generating pulses synchronized to a rising edge of a tachometer signal from rotating machinery are disclosed. For example, in one embodiment, a pulse state machine may be configured to generate a plurality of pulses, and a period state machine may be configured to determine a period for each of the plurality of pulses.

  3. Radiation stability of protein crystals grown by nanostructured templates: synchrotron microfocus analysis

    International Nuclear Information System (INIS)

    Pechkova, Eugenia; Tropiano, Giuseppe; Riekel, Christian; Nicolini, Claudio

    2004-01-01

    X-ray radiation damage of lysozyme single crystals by an intense monochromatic beam from a focussed third-generation synchrotron radiation source has been studied. The preliminary results show a significantly higher resistance to synchrotron radiation of lysozyme microcrystals produced by means of nanotechnology-based template with respect to those prepared by classical methodology. The implications of this finding for protein crystallography are discussed

  4. Small Field-of-view single-shot EPI-DWI of the prostate: Evaluation of spatially-tailored two-dimensional radiofrequency excitation pulses.

    Science.gov (United States)

    Attenberger, Ulrike I; Rathmann, Nils; Sertdemir, Metin; Riffel, Philipp; Weidner, Anja; Kannengiesser, Stefan; Morelli, John N; Schoenberg, Stefan O; Hausmann, Daniel

    2016-06-01

    Spatially-tailored (RF) excitation pulses in echo-planar imaging (EPI), combined with a decreased FOV in the phase-encoding direction, enable a reduction of k-space acquisition lines, which shortens the echo train length (ETL) and reduces susceptibility artifacts. The purpose of this study was to evaluate the image quality of a zoomed EPI (z-EPI) sequence in diffusion-weighted imaging (DWI) of the prostate in comparison to a conventional single-shot EPI using single-channel (c-EPI1) and multi-channel (c-EPI2) RF excitation, with and without use of an endorectal coil. 33 consecutive patients (mean age: 61 +/- 9 years; mean PSA: 8.67±6.23 ng/ml) with examinations between 10/2012 and 02/2014 were analyzed in this retrospective study. In 26 of 33 patients the initial multiparametric (mp)-MRI was performed on a whole-body 3T scanner (Magnetom Trio, Siemens, Erlangen, Germany) using an endorectal coil (c (conventional)-EPI1). Zoomed-EPI (Z-EPI) examinations of these patients and a complete mp-MRI protocol including c-EPI2 of 7 additional patients were carried out on another 3T wb MR scanner with two-channel dynamic parallel transmit capability (Magnetom Skyra with TimTX TrueShape, Siemens). For z-EPI, the one-dimensional spatially selective RF excitation pulse was replaced by a two-dimensional RF pulse. Degree of image blur and susceptibility artifacts (0=not present to 3= non-diagnostic), maximum image distortion (mm), apparent diffusion coefficient (ADC) values, as well as overall scan preference were evaluated. SNR maps were generated to compare c-EPI2 and z-EPI. Overall image quality of z-EPI was preferred by both readers in all examinations with a single exception. Susceptibility artifacts were rated significantly lower on z-EPI compared to both other methods (z-EPI vs c-EPI1: p<0.01; z-EPI vs c-EPI2: p<0.01) as well as image blur (z-EPI vs c-EPI1: p<0.01; z-EPI vs c-EPI2: p<0.01). Image distortion was not statistically significantly reduced with z-EPI (z-EPI vs c

  5. A NEW THERMIONIC RF ELECTRON GUN FOR SYNCHROTRON LIGHT SOURCES

    Energy Technology Data Exchange (ETDEWEB)

    Kutsaev, Sergey; Agustsson, R.; Hartzell, J; Murokh, A.; Nassiri, A.; Savin, E.; Smirnov, A.V.; Smirnov, A. Yu; Sun, Y.; Verma, A; Waldschmidt, Geoff; Zholents, A.

    2017-06-02

    A thermionic RF gun is a compact and efficient source of electrons used in many practical applications. RadiaBeam Systems and the Advanced Photon Source at Argonne National Laboratory collaborate in developing of a reliable and robust thermionic RF gun for synchrotron light sources which would offer substantial improvements over existing thermionic RF guns and allow stable operation with up to 1A of beam peak current at a 100 Hz pulse repetition rate and a 1.5 μs RF pulse length. In this paper, we discuss the electromagnetic and engineering design of the cavity and report the progress towards high power tests of the cathode assembly of the new gun.

  6. Design of a dedicated beamline for THz coherent synchrotron radiation at UVSOR-III

    International Nuclear Information System (INIS)

    Kimura, Shin-ichi; Nakamura, Eiken; Imura, Keiichiro; Katoh, Masahiro; Hosaka, Masahito; Takahashi, Toshiharu

    2012-01-01

    We report the design of a THz beamline for coherent synchrotron radiation (CSR) at the UVSOR-III very-low-emittance synchrotron radiation light source. The emitted THz-CSR is collected by a three-dimensional 'magic mirror', which is a perfect collecting mirror for bending-magnet radiation with an acceptance angle of 288 mrad (H) × 80 mrad (V). A quasi-monochromatic THz-CSR with an average flux of 104 μW/0.1 % b.w. and a peak power of 120 nJ/pulse/0.1 % b.w. is expected at the beamline.

  7. Heavy Ion Injection Into Synchrotrons, Based On Electron String Ion Sources

    CERN Document Server

    Donets, E E; Syresin, E M

    2004-01-01

    A possibility of heavy ions injection into synchrotrons is discussed on the base of two novel ion sources, which are under development JINR during last decade: 1) the electron string ion source (ESIS), which is a modified version of a conventional electron beam ion source (EBIS), working in a reflex mode of operation, and 2) the tubular electron string ion source (TESIS). The Electron String Ion Source "Krion-2" (VBLHE, JINR, Dubna) with an applied confining magnetic field of 3 T was used for injection into the superconducting JINR synchrotron - Nuclotron and during this runs the source provided a high pulse intensity of the highly charged ion beams: Ar16+

  8. Synchrotron Environmental Science-I Workshop Report

    International Nuclear Information System (INIS)

    1999-01-01

    Attendees of the Synchrotrons Environmental Science 1 (SES-1) workshop represented a broad spectrum of environmental science research areas and expertise in all of the current synchrotrons techniques (X-ray scattering and diffraction, X-ray absorption spectroscopy, and two- and three-dimensional X-ray imaging). These individuals came together to discuss current measurement obstacles in environmental research and, more specifically, ways to overcome such obstacles by applying synchrotrons radiation techniques. Significant obstacles in measurement affect virtually all of the research issues described. Attendees identified synchrotrons approaches of potential value in their research. A number of the environmental research studies discussed are currently being addressed with some success by synchrotron-based approaches. Nevertheless, improvements in low-Z measurement capabilities are needed to facilitate the use of synchrotrons radiation methodologies in environmental research

  9. Synchrotron Environmental Science-I Workshop Report.

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-08

    Attendees of the Synchrotrons Environmental Science 1 (SES-1) workshop represented a broad spectrum of environmental science research areas and expertise in all of the current synchrotrons techniques (X-ray scattering and diffraction, X-ray absorption spectroscopy, and two- and three-dimensional X-ray imaging). These individuals came together to discuss current measurement obstacles in environmental research and, more specifically, ways to overcome such obstacles by applying synchrotrons radiation techniques. Significant obstacles in measurement affect virtually all of the research issues described. Attendees identified synchrotrons approaches of potential value in their research. A number of the environmental research studies discussed are currently being addressed with some success by synchrotron-based approaches. Nevertheless, improvements in low-Z measurement capabilities are needed to facilitate the use of synchrotrons radiation methodologies in environmental research.

  10. Light source for synchrotron radiation x-ray topography study at Beijing Synchrotron Radiation Laboratory (BSRL)

    International Nuclear Information System (INIS)

    Zhao Jiyong; Jiang Jianhua; Tian Yulian

    1992-01-01

    Characteristics of the synchrotron radiation source for X-ray topography study at Beijing Synchrotron Radiation Laboratory (BSRL) is described, local geometrical resolution of topographies is discussed, and the diffracting intensities of white beam topography is given

  11. Optical synchrotron radiation beam imaging with a digital mask

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Hao [Univ. of Maryland, College Park, MD (United States); Fiorito, Ralph [Univ. of Maryland, College Park, MD (United States); Corbett, Jeff [SLAC National Accelerator Lab., Menlo Park, CA (United States); Shkvarunets, Anatoly [Univ. of Maryland, College Park, MD (United States); Tian, Kai [SLAC National Accelerator Lab., Menlo Park, CA (United States); Fisher, Alan [SLAC National Accelerator Lab., Menlo Park, CA (United States); Douglas, D. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Wilson, F. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Zhang, S. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Mok, W. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Mitsuhashi, T. [KEK, Tsukuba (Japan)

    2016-01-01

    The 3GeV SPEAR3 synchrotron light source operates in top-up injection mode with up to 500mA circulating in the storage ring (equivalently 392nC). Each injection pulse contains only 40-80 pC producing a contrast ratio between total stored charge and injected charge of about 6500:1. In order to study transient injected beam dynamics during User operations, it is desirable to optically image the injected pulse in the presence of the bright stored beam. In the present work this is done by re-imaging visible synchrotron radiation onto a digital micro-mirror-array device (DMD), which is then used as an optical mask to block out light from the bright central core of the stored beam. The physical masking, together with an asynchronously-gated, ICCD imaging camera makes it is possible to observe the weak injected beam component on a turn-by-turn basis. The DMD optical masking system works similar to a classical solar coronagraph but has some distinct practical advantages: i.e. rapid adaption to changes in the shape of the stored beam, high extinction ratio for unwanted light and minimum scattering from the primary beam into the secondary optics. In this paper we describe the DMD masking method, features of the high dynamic range point spread function for the SPEAR3 optical beam line and measurements of the injected beam in the presence of the stored beam.

  12. Synchrotron Radiation in Biology and Medicine

    International Nuclear Information System (INIS)

    Pelka, J.B.

    2008-01-01

    This work is focused on a present status of synchrotron radiation X-ray applications in medicine and biology to imaging, diagnostics, and radio- therapy. Properties of X-ray beams generated by synchrotron sources are compared with radiation produced by classical laboratory X-ray tubes. A list of operating and planned synchrotron facilities applicable to biomedical purposes is given, together with their basic characteristics. A concise overview of typical X-ray synchrotron techniques in biology and medicine is carried out with discussion of their specific properties and examples of typical results. (author)

  13. Atomic physics research with synchrotron radiation

    International Nuclear Information System (INIS)

    Crasemann, B.; Wuilleumier, F.

    1985-01-01

    This chapter discusses applications of synchrotron light in atomic and molecular physics. Use of the radiation from storage rings has expanded and lent access to new areas of absorption and photoemission spectroscopy and scattering experiments. Techniques applied in connection with synchrotron radiation are discussed including absorption spectroscopy, photoelectron spectroscopy, fluorescence spectroscopy and X-ray scattering. Problem areas that are being studied by the techniques mentioned above are discussed. Synchrotron radiation has provided the means for measuring the threshold-excitation and interference effects that signal the breakdown of the two-step model of atomic excitation/deexcitation. Synchrotron radiation provides more means of excited-state photoionization measurements

  14. Support for Synchrotron Access by Environmental Scientists

    International Nuclear Information System (INIS)

    Daly, Michael; Madden, Andrew; Palumbo, Anthony; Qafoku, N.

    2006-01-01

    To support ERSP-funded scientists in all aspects of synchrotron-based research at the Advanced Photon Source (APS). This support comes in one or more of the following forms: (1) writing proposals to the APS General User (GU) program, (2) providing time at MRCAT/EnviroCAT beamlines via the membership of the Molecular Environmental Science (MES) Group in MRCAT/EnviroCAT, (3) assistance in experimental design and sample preparation, (4) support at the beamline during the synchrotron experiment, (5) analysis and interpretation of the synchrotron data, and (6) integration of synchrotron experimental results into manuscripts

  15. Assessment of Event-Related EEG Power After Single-Pulse TMS in Unresponsive Wakefulness Syndrome and Minimally Conscious State Patients.

    Science.gov (United States)

    Formaggio, Emanuela; Cavinato, Marianna; Storti, Silvia Francesca; Tonin, Paolo; Piccione, Francesco; Manganotti, Paolo

    2016-03-01

    In patients without a behavioral response, non-invasive techniques and new methods of data analysis can complement existing diagnostic tools by providing a method for detecting covert signs of residual cognitive function and awareness. The aim of this study was to investigate the brain oscillatory activities synchronized by single-pulse transcranial magnetic stimulation (TMS) delivered over the primary motor area in the time-frequency domain in patients with the unresponsive wakefulness syndrome or in a minimally conscious state as compared to healthy controls. A time-frequency analysis based on the wavelet transform was used to characterize rapid modifications of oscillatory EEG rhythms induced by TMS in patients as compared to healthy controls. The pattern of EEG changes in the patients differed from that of healthy controls. In the controls there was an early synchronization of slow waves immediately followed by a desynchronization of alpha and beta frequency bands over the frontal and centro-parietal electrodes, whereas an opposite early synchronization, particularly over motor areas for alpha and beta and over the frontal and parietal electrodes for beta power, was seen in the patients. In addition, no relevant modification in slow rhythms (delta and theta) after TMS was noted in patients. The clinical impact of these findings could be relevant in neurorehabilitation settings for increasing the awareness of these patients and defining new treatment procedures.

  16. Kinetics of the Thermal Decomposition of Tetramethylsilane behind the Reflected Shock Waves in a Single Pulse Shock Tube (SPST) and Modeling Study

    Science.gov (United States)

    Parandaman, A.; Sudhakar, G.; Rajakumar, B.

    Thermal reactions of Tetramethylsilane (TMS) diluted in argon were studied behind the reflected shock waves in a single-pulse shock tube (SPST) over the temperature range of 1085-1221 K and pressures varied between 10.6 and 22.8 atm. The stable products resulting from the decomposition of TMS were identified and quantified using gas chromatography and also verified with Fourier Transform Infrared (FTIR) spectrometer. The major reaction products are methane (CH4) and ethylene (C2H4). The minor reaction products are ethane (C2H6) and propylene (C3H6). The initiation of mechanism in the decomposition of TMS takes plays via the Si-C bond scission by ejecting the methyl radicals (CH3) and trimethylsilyl radicals ((CH3)3Si). The measured temperature dependent rate coefficient for the total decomposition of TMS was to be ktotal = 1.66 ×1015 exp (-64.46/RT) s-1 and for the formation of CH4 reaction channel was to be k = 2.20 × 1014 exp (-60.15/RT) s-1, where the activation energies are given in kcal mol-1. A kinetic scheme containing 17 species and 28 elementary reactions was used for the simulation using chemical kinetic simulator over the temperature range of 1085-1221 K. The agreement between the experimental and simulated results was satisfactory.

  17. Double Pass 595 nm Pulsed Dye Laser Does Not Enhance the Efficacy of Port Wine Stains Compared with Single Pass: A Randomized Comparison with Histological Examination.

    Science.gov (United States)

    Yu, Wenxin; Zhu, Jiafang; Wang, Lizhen; Qiu, Yajing; Chen, Yijie; Yang, Xi; Chang, Lei; Ma, Gang; Lin, Xiaoxi

    2018-03-27

    To compare the efficacy and safety of double-pass pulsed dye laser (DWL) and single-pass PDL (SWL) in treating virgin port wine stain (PWS). The increase in the extent of vascular damage attributed to the use of double-pass techniques for PWS remains inconclusive. A prospective, side-by-side comparison with a histological study for virgin PWS is still lacking. Twenty-one patients (11 flat PWS, 10 hypertrophic PWS) with untreated PWS underwent 3 treatments at 2-month intervals. Each PWS was divided into three treatment sites: SWL, DWL, and untreated control. Chromametric and visual evaluation of the efficacy and evaluation of side effects were conducted 3 months after final treatment. Biopsies were taken at the treated sites immediately posttreatment. Chromametric and visual evaluation suggested that DWL sites showed no significant improvement compared with SWL (p > 0.05) in treating PWS. The mean depth of photothermal damage to the vessels was limited to a maximum of 0.36-0.41 mm in both SWL and DWL sides. Permanent side effects were not observed in any patients. Double-pass PDL does not enhance PWS clearance. To improve the clearance of PWS lesions, either the depth of laser penetration should be increased or greater photothermal damage to vessels should be generated.

  18. A Study of Cortical Excitability, Central Motor Conduction, and Cortical Inhibition Using Single Pulse Transcranial Magnetic Stimulation in Patients with Early Frontotemporal and Alzheimer's Dementia.

    Science.gov (United States)

    Chandra, Sadanandavalli Retnaswami; Issac, Thomas Gregor; Nagaraju, B C; Philip, Mariamma

    2016-01-01

    Degenerative cortical dementias affect several million people worldwide. Early diagnosis and categorization are essential for initiating appropriate pharmacological and nonpharmacological treatment so that deterioration can be postponed, and disability adjusted life years can be saved both for the patient and for the caregiver. Therefore, an early, simple, noninvasive biomarker will serve as a boon. Patients who satisfied probable Alzheimer's disease (AD) or frontotemporal dementia (FTD) using international consensus criteria for FTD and National Institute of Neurological Disorders and Stroke-AD and Related Disorders Association criteria for AD were evaluated using single pulse transcranial magnetic stimulation with figure of eight coil and motor evoked potential from right first dorsal interossei. Resting threshold (MT), central motor conduction time (CMCT), and silent period (SP) were evaluated. Resting MT and SP are reduced in patients with Alzheimer's disease whereas CMCT is prolonged in patients with FTD and SP is in the lower limit of normal in both conditions. The patterns of central motor conduction and MT are distinctly different in patients with early Alzheimer's disease (AD) and FTD.

  19. Low temperature pulsed direct current magnetron sputtering technique for single phase β-In2S3 buffer layers for solar cell applications

    Science.gov (United States)

    Karthikeyan, Sreejith; Hill, Arthur E.; Pilkington, Richard D.

    2017-10-01

    This work explores the possibilities of using the pulsed direct current (dc) magnetron sputtering (PDCMS) process to deposit an alternative to the cadmium sulphide buffer layer in copper indium gallium diselenide - based solar cells. The main problems with the CdS layer are its toxic nature and its deposition using a chemical bath technique. These factors make it difficult to incorporate into in-line production and significant effort has been expended to find a suitable alternative buffer layer with in-line manufacturing capability. Towards this aim, the material properties of an In2S3 film, sputtered from a powder target, have been investigated. Films were deposited at different substrate temperatures ranging from ;no additional substrate heating; to 250 °C. The deposition of a single phase β-In2S3 without substrate heating/annealing has not previously been reported. The films deposited by the ion-enhanced PdcMS technique without any additional heating were found to be single phase. The grain size increased with increase in substrate temperature. However, this led to a decrease in the sulphur content; as a result the band gap decreased. For solar cell applications, the CdS buffer layer (optical band gap ∼2.4 eV) needs to be replaced with a material which has a band gap wider than 2.4 eV for improved performance and reduction of absorption loss in the blue wavelength region. Ideally the band gap should be between 2.6 and 3.0 eV. Our PdcMS room temperature deposited In2S3 had a measured band gap of 2.77 eV.

  20. Real-time monitoring of longitudinal electron bunch parameters by intensity-integrated and spectroscopic measurements of single coherent THz pulses

    International Nuclear Information System (INIS)

    Wesch, Stephan

    2012-12-01

    High-gain free-electron lasers (FELs) generate intense and monochromatic photon pulses with few tens of femtosecond duration. For this purpose, electron beams are accelerated to relativistic energies and shrunk longitudinally down to micrometer size.The diagnosis of theses compressed electron bunches is a challenge especially for MHz bunch repetition rates as provided by the FEL FLASH in Hamburg. In this thesis, coherently emitted THz radiation of single electron bunches were investigated, on which the longitudinal structure is imprinted. Two instruments were used: First, the FLASH bunch compression monitors, relying on the integrated intensity measurement of diffraction radiation, were modified to determine the overall length of every bunch behind the two bunch compressors (BC). A model was developed showing that their response is independent of the exact bunch shape for lengths below 200 μm (rms). This could experimentally be verified in the range between 50 and 190 μm within 7% accuracy for themonitor behind the last BC by comparison with measurements with the transverse deflecting structure (TDS). Second, a single-shot spectrometer with five staged reflective blazed gratings has been designed, build and commissioned. With its two grating sets, the wavelength ranges from 5.5 to 44 μm and 45 to 440 μm can be simultaneously detected by 118 fast pyroelectric elements. Measurements based on transition radiation spectra were compared with profiles recorded by the TDS.The shape of the spectra as well as the reconstructed temporal profiles (using the Kramers-Kronig relation for phase retrieval) are in excellent agreement. For bunches with a charge of 50 pC, bunch lengths down to 5 μm (fhwm) could be detected.

  1. Sensitivities in synchrotron radiation TXRF

    International Nuclear Information System (INIS)

    Pianetta, P.; Baur, K.; Brennan, S.

    2000-01-01

    This work describes the progress we achieved at the Stanford Synchrotron Radiation Laboratory (SSRL) in improving the sensitivity for both the transition metals and light elements such as Al and Na. The transition metal work has matured to the point where a facility exists at SSRL in which semiconductor companies are able to perform industrially relevant measurements at state of the art detection limits. This facility features clean wafer handling and automated data acquisition making routine analytical measurements possible. The best sensitivity demonstrated so far is 3.4 E7 atoms/cm 2 for a 5000 second count time corresponding to 7.6 E7 atoms/cm 2 for a standard 1000 second count time. This is more than a factor of 100 better than what can be achieved with conventional TXRF systems. The detection of light elements such as Al and Na is challenging due to the presence of the h stronger Si fluorescence peak. For traditional energy-dispersive detection only the tunability of synchrotron radiation to excitation energies below the Si-K absorption edge leads to an acceptable sensitivity for Al detection which is limited by a large background due to inelastic x-ray Raman scattering. An alternative approach to overcome the Raman contribution and the strong Si fluorescence is to use a wavelength-dispersive spectrometer for fluorescence detection. The benefits of such a multilayer spectrometer over a solid state detector are its higher energy resolution and greater dynamic range. This strategy allows primary excitation above the Si K absorption edge, eliminating the background due to Raman scattering, and a gracing emission geometry to guarantee high surface sensitivity. Studies testing this concept in combination with high flux synchrotron radiation are underway and first results will be presented. (author)

  2. Vacuum system for HIMAC synchrotrons

    International Nuclear Information System (INIS)

    Kanazawa, M.; Sudou, M.; Sato, K.

    1994-01-01

    HIMAC synchrotrons are now under construction, which require vacuum chambers of large aperture and high vacuum of about 10 -9 torr. Wide thin wall vacuum chamber of 0.3 mm thickness reinforced with ribs has been developed as the chamber at dipole magnet. We have just now started to evacuate the lower ring. The obtained average value was about 5x10 -8 torr with turbo-molecular and sputter ion pumps, and 1.1x10 -9 torr after baking. (author)

  3. Synchrotron light and its uses

    International Nuclear Information System (INIS)

    Blewett, J.P.

    1978-01-01

    It was known for a century that charged particles radiate when accelerated and that relativistic electrons in the energy range between 100 MeV and several GeV and constrained to travel in circular orbits emit concentrated, intense beams with broad continuous spectra that can cover the electromagnetic spectrum from infrared through hard x-rays. Recently the possible applications of this radiation were appreciated and electron synchrotrons and electron storage rings are now being used in many centers for studies of the properties of matter in the solid, liquid and gaseous states. 10 references

  4. Serial crystallography using synchrotron radiation

    OpenAIRE

    Rossmann, Michael G.

    2014-01-01

    A brief history is given of how X-ray diffraction data from crystals have been recorded. Today there are new possibilities, spawned by the availability of free electron lasers that produce powerful femtosecond long X-ray pulses.

  5. Serial crystallography using synchrotron radiation.

    Science.gov (United States)

    Rossmann, Michael G

    2014-03-01

    A brief history is given of how X-ray diffraction data from crystals have been recorded. Today there are new possibilities, spawned by the availability of free electron lasers that produce powerful femtosecond long X-ray pulses.

  6. Photoemission spectroscopy using synchrotron radiation

    International Nuclear Information System (INIS)

    Kobayashi, K.L.I.

    1980-01-01

    It is an epoch making event for photoemission spectroscopy that the light sources of continuous wavelength from vacuum ultra-violet to X-ray region have become available by the advent of synchrotron radiation. Specifically the progress after stable intense light has become obtainable from storage rings is very significant. One of the features of these synchrotron radiation is its extreme polarization of radiating pattern. Though the elementary processes of photoemission out of solids are the basic themes, phenomenalistic 3-stage model is usually applied to the analysis of experiments. In this model, the process of photoemission is considered by dividing into three stages, namely the generation of photoelectrons due to optical transition between electron status -- the transportation of photoelectrons to solid surfaces -- breaking away from the surfaces. The spectrometers, the energy analyzers of photoelectrons, and sample-preparing room used for photoemission spectroscopy are described. Next, energy distribution curves are explained. At the end, photoelectron yield spectroscopy, CFS (constant final energy spectroscopy) and CIS (constant initial energy spectroscopy), Auger yield and interatomic Auger yield, the determination of surface structure by normal emission CIS, and surface EXAFS (extended X-ray absorption fine structure) are described. As seen above, the application specifically to surface physics is promising in the future. (Wakatsuki, Y.)

  7. Sirepo for Synchrotron Radiation Workshop

    Energy Technology Data Exchange (ETDEWEB)

    2016-10-25

    Sirepo is an open source framework for cloud computing. The graphical user interface (GUI) for Sirepo, also known as the client, executes in any HTML5 compliant web browser on any computing platform, including tablets. The client is built in JavaScript, making use of the following open source libraries: Bootstrap, which is fundamental for cross-platform web applications; AngularJS, which provides a model–view–controller (MVC) architecture and GUI components; and D3.js, which provides interactive plots and data-driven transformations. The Sirepo server is built on the following Python technologies: Flask, which is a lightweight framework for web development; Jinja, which is a secure and widely used templating language; and Werkzeug, a utility library that is compliant with the WSGI standard. We use Nginx as the HTTP server and proxy, which provides a scalable event-driven architecture. The physics codes supported by Sirepo execute inside a Docker container. One of the codes supported by Sirepo is the Synchrotron Radiation Workshop (SRW). SRW computes synchrotron radiation from relativistic electrons in arbitrary magnetic fields and propagates the radiation wavefronts through optical beamlines. SRW is open source and is primarily supported by Dr. Oleg Chubar of NSLS-II at Brookhaven National Laboratory.

  8. Study of spear as a dedicated source of synchrotron radiation

    International Nuclear Information System (INIS)

    Cerino, J.; Golde, A.; Hastings, J.; Lindau, I.; Salsburg, B.; Winick, H.; Lee, M.; Morton, P.; Garren, A.

    1977-11-01

    A study was made of the potential of SPEAR as a dedicated source of synchrotron radiation, based on the expectation that SPEAR will become increasingly available for this purpose as PEP, the 18-GeV colliding-beam storage ring now under construction by LBL and SLAC, becomes operational. A synchrotron radiation research program has been underway since May, 1974. Two beam ports capable of serving 9 simultaneous users are now operational. In single-beam multi-bunch operation high currents are possible (225 mA has been achieved and > approximately 300 mA is expected) and the electron beam emittance can be made smaller, resulting in higher source point brightness. Descriptions are given of SPEAR capabilities and of plans to expand the research capability by adding beam runs and by inserting wiggler magnets in SPEAR straight sections

  9. Synchrotron radiation in transactinium research report of the workshop

    International Nuclear Information System (INIS)

    1992-11-01

    This report contains viewgraphs on the following topics. The advanced light source U8 undulator beamline, 20--300 eV; gas-phase actinide studies with synchrotron radiation; atomic structure calculations for heavy atoms; flux growth of single crystal uranium intermetallics: Extension to transuranics; x-ray absorption near-edge structure studies of actinide compounds; surface as a new stage for studying actinides: Theoretical study of the surface electronic structure of uranium; magnetic x-ray scattering experiments at resonant energies; beamline instruments for radioactive materials; the search for x-ray absorption magnetic circular dichroism in actinide materials: preliminary experiments using UFe 2 and U-S; the laser plasma laboratory light source: a source of preliminary transuranic data; electron spectroscopy of heavy fermion actinide materials; study of thin layers of actinides. Present status and future use of synchrotron radiation; electronic structure and correlated-electron theory for actinide materials; and heavy fermion and kondo phenomena in actinide materials

  10. SR TXRF: performances and perspectives of a dedicated synchrotron beamline

    International Nuclear Information System (INIS)

    Comin, F.; Apostolo, G.

    2000-01-01

    In principle the brilliance of synchrotron radiation x-ray beams combined with a high degree of linear polarization allows to reach at the same time low LLDs, mapping of the impurity distribution and chemical identification for elements as light as Na. The TXRF facility at the European synchrotron radiation facility is installed along a beamline dedicated to industry and is designed to reach ultimate detection limits of 6 x 10 7 at/cm 2 in selected areas, or to map the concentration of contaminants with LLD in the scale 10 9 at/cm 2 . In the present configuration the facility works in vacuum with a single element detector. Loading, unloading and pump down of wafers is completely automatic. Typical DDLs are of few 10 9 at/cm 2 for Na and Al and 10 8 at/cm 2 for transition metals. Absorption spectra (XANES and EXAFS) of TM help in the defining the chemistry of the contaminant. (author)

  11. Development of a synchrotron timing system on a programmable chip

    International Nuclear Information System (INIS)

    Lin Feiyu; Qiao Weimin; Wang Yanyu; Guo Yuhui

    2009-01-01

    A synchrotron requires extremely high time constraints for timing signals, so timing system is very important for a synchrotron control system. A FPGA+ARM+Linux+DSP architecture has been mainly used in timing control of the HIRFL-CSR control system. In this paper, we report the development of the SOPC(System On a Programmable Chip) based on FPGA and uClinux.It can integrate all the functions of ARM+Linux in one single FPGA chip, hence no need of the dedicated ARM chip, and the reduced cost. The maximum operation frequency of this system is 185 MHz. The hardware consumes less than 4% of total resources of FPGA chip. And both the hardware system and the operating system of the SOPC are reconfigurable. The SOPC system has a wide prospect of applications in accelerator engineering and many fields of scientific research. (authors)

  12. Synchrotron applications in wood preservation and deterioration

    Science.gov (United States)

    Barbara L. Illman

    2003-01-01

    Several non-intrusive synchrotron techniques are being used to detect and study wood decay. The techniques use high intensity synchrotron-generated X-rays to determine the atomic structure of materials with imaging, diffraction, and absorption. Some of the techniques are X-ray absorption near edge structure (XANES), X-ray fluorescence spectroscopy (XFS), X-ray...

  13. High pressure and synchrotron radiation satellite workshop

    International Nuclear Information System (INIS)

    Bass, J.; Guignot, N.; Morard, G.; Mezouar, M.; Andrault, D.; Bolfan-Casanova, N.; Sturhahn, W.; Daniel, I.; Reynard, B.; Simionovici, A.; Sanchez Valle, C.; Martinez, I.; Kantor, I.; Dubrovinsky, I.; Mccammon, C.; Dubrovinskaia, N.; Kurnosiv, A.; Kuznetsov, A.; Goncharenko, I.; Loubeyre, P.; Desgreniers, S.; Weck, G.; Yoo, C.S.; Iota, V.; Park, J.; Cynn, H.; Gorelli, F.; Toulemonde, P.; Machon, D.; Merlen, A.; San Miguel, A.; Amboage, M.; Aquilanti, G.; Mathon, O.; Pascarelli, S.; Itie, J.P.; Mcmillan, P.F.; Trapananti, A.; Di Cicco, A.; Panfilis, S. de; Filipponi, A.; Kreisel, J.; Bouvier, P.; Dkhil, B.; Chaabane, B.; Rosner, H.; Koudela, D.; Schwarz, U.; Handestein, A.; Hanfland, M.; Opahle, I.; Koepernik, K.; Kuzmin, M.; Mueller, K.H.; Mydosh, J.; Richter, M.; Hejny, C.; Falconi, S.; Lundegaard, L.F.; Mcmahon, M.I; Loa, I.; Syassen, K.; Wang, X.; Roth, H.; Lorenz, T.; Farber Daniel, I.; Antonangeli Daniele, I.; Krisch, M.; Badro, J.; Fiquet, G.; Occelli, F.; Mao, W.L.; Mao, H.K.; Eng, P.; Kao, C.C.; Shu, J.F.; Hemley, R.J.; Tse, J.S.; Yao, Y.; Deen, P.P.; Paolasini, I.; Braithwaite, D.; Kernavanois, N.; Lapertot, G.; Rupprecht, K.; Leupold, O.; Ponkratz, U.; Wortmann, G.; Beraud, A.; Krisch, M.; Farber, D.; Antonangeli, D.; Aracne, C.; Zarestky, J.L.; Mcqueeney, R.; Mathon, O.; Baudelet, F.; Decremps, F.; Itie, J.P.; Nataf, I.; Pascarelli, S.; Polian, A.

    2006-01-01

    The workshop is dedicated to recent advances on science at high pressure at third generation synchrotron sources. A variety of experiments using synchrotron radiation techniques including X-ray diffraction, EXAFS (extended X-ray absorption fine structure), inelastic X-ray scattering, Compton scattering and Moessbauer spectroscopy of crystalline, liquid or amorphous samples, are reported. This document gathers the abstracts of the presentations

  14. High-Intensity Synchrotron Radiation Effects

    CERN Document Server

    Suetsugu, Y.

    2016-01-01

    Various effects of intense synchrotron radiation on the performance of particle accelerators, especially for storage rings, are discussed. Following a brief introduction to synchrotron radiation, the basic concepts of heat load, gas load, electron emission, and the countermeasures against these effects are discussed.

  15. High pressure and synchrotron radiation satellite workshop

    Energy Technology Data Exchange (ETDEWEB)

    Bass, J.; Guignot, N.; Morard, G.; Mezouar, M.; Andrault, D.; Bolfan-Casanova, N.; Sturhahn, W.; Daniel, I.; Reynard, B.; Simionovici, A.; Sanchez Valle, C.; Martinez, I.; Kantor, I.; Dubrovinsky, I.; Mccammon, C.; Dubrovinskaia, N.; Kurnosiv, A.; Kuznetsov, A.; Goncharenko, I.; Loubeyre, P.; Desgreniers, S.; Weck, G.; Yoo, C.S.; Iota, V.; Park, J.; Cynn, H.; Gorelli, F.; Toulemonde, P.; Machon, D.; Merlen, A.; San Miguel, A.; Amboage, M.; Aquilanti, G.; Mathon, O.; Pascarelli, S.; Itie, J.P.; Mcmillan, P.F.; Trapananti, A.; Di Cicco, A.; Panfilis, S. de; Filipponi, A.; Kreisel, J.; Bouvier, P.; Dkhil, B.; Chaabane, B.; Rosner, H.; Koudela, D.; Schwarz, U.; Handestein, A.; Hanfland, M.; Opahle, I.; Koepernik, K.; Kuzmin, M.; Mueller, K.H.; Mydosh, J.; Richter, M.; Hejny, C.; Falconi, S.; Lundegaard, L.F.; Mcmahon, M.I; Loa, I.; Syassen, K.; Wang, X.; Roth, H.; Lorenz, T.; Farber Daniel, I.; Antonangeli Daniele, I.; Krisch, M.; Badro, J.; Fiquet, G.; Occelli, F.; Mao, W.L.; Mao, H.K.; Eng, P.; Kao, C.C.; Shu, J.F.; Hemley, R.J.; Tse, J.S.; Yao, Y.; Deen, P.P.; Paolasini, I.; Braithwaite, D.; Kernavanois, N.; Lapertot, G.; Rupprecht, K.; Leupold, O.; Ponkratz, U.; Wortmann, G.; Beraud, A.; Krisch, M.; Farber, D.; Antonangeli, D.; Aracne, C.; Zarestky, J.L.; Mcqueeney, R.; Mathon, O.; Baudelet, F.; Decremps, F.; Itie, J.P.; Nataf, I.; Pascarelli, S.; Polian, A

    2006-07-01

    The workshop is dedicated to recent advances on science at high pressure at third generation synchrotron sources. A variety of experiments using synchrotron radiation techniques including X-ray diffraction, EXAFS (extended X-ray absorption fine structure), inelastic X-ray scattering, Compton scattering and Moessbauer spectroscopy of crystalline, liquid or amorphous samples, are reported. This document gathers the abstracts of the presentations.

  16. Funding problems threaten Middle East's synchrotron

    CERN Multimedia

    McCabe, H

    1999-01-01

    Scientists will tour the Middle East to try to raise support for the Synchrotron radiation for Experimental Science and Applications in the Middle East project. The plan is to dismantle and move a decommissioned synchrotron from Berlin to the Middle East where scientists of any nationality would be able to use it (3 paragraphs).

  17. Protein Data Bank Depositions from Synchrotron Sources

    International Nuclear Information System (INIS)

    Jiang, J.; Sweet, R.

    2004-01-01

    A survey and analysis of Protein Data Bank (PDB) depositions from international synchrotron radiation facilities, based on the latest released PDB entries, are reported. The results ( ) show that worldwide, every year since 1999, more than 50% of the deposited X-ray structures have used synchrotron facilities, reaching 75% by 2003. In this web-based database, all PDB entries among individual synchrotron beamlines are archived, synchronized with the weekly PDB release. Statistics regarding the quality of experimental data and the refined model for all structures are presented, and these are analysed to reflect the impact of synchrotron sources. The results confirm the common impression that synchrotron sources extend the size of structures that can be solved with equivalent or better quality than home sources

  18. Some feature of interpretation of tension single pulsed electromagnetic field of the Earth to create the model parameter fields physical properties

    Directory of Open Access Journals (Sweden)

    Mokritskaya T.P.

    2014-12-01

    Full Text Available Stochastic analysis of the results of different methods of obtaining and processing of information allows us to solve problems on a qualitatively different level. This is important when creating complex earth models and fields of its parameters, particularly the physical properties. Application of remote sensing methods (geophysical investigations with the registration of a single pulse intensity of the electromagnetic field of the Earth (EIEMPZ seismic profiling, is expanding. Interesting results of the joint interpretation of the results of geophysical and laboratory studies of physical soil. Interesting results of the joint interpretation of the results of geophysical and laboratory studies of physical soil. For the first time a methodology for assessing the state of the soil [3] applied for a joint interpretation of materials determine the field strength EMPZ, seismic profiling, and laboratory techniques. This has allowed to characterize the state of the geological environment and to build a model of inhomogeneous density distribution of fractured rocks at depth. In this paper we made a mathematical analysis of the results of research and talus deposits eluvial clay Taurian series, studied at one of the construction sites southern coast at a depth of 12.0 -25.0 m. Methods of statistical analysis, assessment of homogeneity and symmetrically distributed, rank correlation and multiple regression analysis described in [3]. The analysis of the spatial distribution of areas extrem value of EMPZ, heterogeneity of seismic rigidity. Statistical characteristics of indicators of physical properties reflect the genetic characteristics of the formation and the current state of silty-clay sediments of different genesis.It is proved that the regression model can be applied to interpret the state of the array in the construction of geodynamic model. It is established that the creation of forward-looking (dynamic models for the distribution of the physical

  19. The Effects of a Single Developmentally Entrained Pulse of Testosterone in Female Neonatal Mice on Reproductive and Metabolic Functions in Adult Life.

    Science.gov (United States)

    Jang, Hyeran; Bhasin, Shalender; Guarneri, Tyler; Serra, Carlo; Schneider, Mary; Lee, Mi-Jeong; Guo, Wen; Fried, Susan K; Pencina, Karol; Jasuja, Ravi

    2015-10-01

    Early postnatal exposures to sex steroids have been well recognized to modulate predisposition to diseases of adulthood. There is a complex interplay between timing, duration and dose of endocrine exposures through environmental or dietary sources that may alter the sensitivity of target tissues to the exogenous stimuli. In this study, we determined the metabolic and reproductive programming effects of a single developmentally entrained pulse of testosterone (T) given to female mice in early postnatal period. CD-1 female mice pups were injected with either 5 μg of T enanthate (TE) or vehicle (control [CON] group) within 24 hours after birth and followed to adult age. A total of 66% of T-treated mice exhibited irregular cycling, anovulatory phenotype, and significantly higher ovarian weights than vehicle-treated mice. Longitudinal nuclear magnetic resonance measurements revealed that TE group had greater body weight, whole-body lean, and fat mass than the CON group. Adipose tissue cellularity analysis in TE group revealed a trend toward higher size and number than their littermate CONs. The brown adipose tissue of TE mice exhibited white fat infiltration with down-regulation of several markers, including uncoupling protein 1 (UCP-1), cell death-inducing DNA fragmentation factor, α-subunit-like effector A, bone morphogenetic protein 7 as well as brown adipose tissue differentiation-related transcription regulators. T-injected mice were also more insulin resistant than CON mice. These reproductive and metabolic reprogramming effects were not observed in animals exposed to TE at 3 and 6 weeks of age. Collectively, these data suggest that sustained reproductive and metabolic alterations may result in female mice from a transient exposure to T during a narrow postnatal developmental window.

  20. Evaluating scintillator performance in time-resolved hard X-ray studies at synchrotron light sources

    International Nuclear Information System (INIS)

    Rutherford, Michael E.; Chapman, David J.; White, Thomas G.; Drakopoulos, Michael; Rack, Alexander; Eakins, Daniel E.

    2016-01-01

    Scintillator performance in time-resolved, hard, indirect detection X-ray studies on the sub-microsecond timescale at synchrotron light sources is reviewed, modelled and examined experimentally. LYSO:Ce is found to be the only commercially available crystal suitable for these experiments. The short pulse duration, small effective source size and high flux of synchrotron radiation is ideally suited for probing a wide range of transient deformation processes in materials under extreme conditions. In this paper, the challenges of high-resolution time-resolved indirect X-ray detection are reviewed in the context of dynamic synchrotron experiments. In particular, the discussion is targeted at two-dimensional integrating detector methods, such as those focused on dynamic radiography and diffraction experiments. The response of a scintillator to periodic synchrotron X-ray excitation is modelled and validated against experimental data collected at the Diamond Light Source (DLS) and European Synchrotron Radiation Facility (ESRF). An upper bound on the dynamic range accessible in a time-resolved experiment for a given bunch separation is calculated for a range of scintillators. New bunch structures are suggested for DLS and ESRF using the highest-performing commercially available crystal LYSO:Ce, allowing time-resolved experiments with an interframe time of 189 ns and a maximum dynamic range of 98 (6.6 bits)

  1. Evaluating scintillator performance in time-resolved hard X-ray studies at synchrotron light sources

    Energy Technology Data Exchange (ETDEWEB)

    Rutherford, Michael E.; Chapman, David J.; White, Thomas G. [Imperial College London, London (United Kingdom); Drakopoulos, Michael [Diamond Light Source, I12 Joint Engineering, Environmental, Processing (JEEP) Beamline, Didcot, Oxfordshire (United Kingdom); Rack, Alexander [European Synchrotron Radiation Facility, Grenoble (France); Eakins, Daniel E., E-mail: d.eakins@imperial.ac.uk [Imperial College London, London (United Kingdom)

    2016-03-24

    Scintillator performance in time-resolved, hard, indirect detection X-ray studies on the sub-microsecond timescale at synchrotron light sources is reviewed, modelled and examined experimentally. LYSO:Ce is found to be the only commercially available crystal suitable for these experiments. The short pulse duration, small effective source size and high flux of synchrotron radiation is ideally suited for probing a wide range of transient deformation processes in materials under extreme conditions. In this paper, the challenges of high-resolution time-resolved indirect X-ray detection are reviewed in the context of dynamic synchrotron experiments. In particular, the discussion is targeted at two-dimensional integrating detector methods, such as those focused on dynamic radiography and diffraction experiments. The response of a scintillator to periodic synchrotron X-ray excitation is modelled and validated against experimental data collected at the Diamond Light Source (DLS) and European Synchrotron Radiation Facility (ESRF). An upper bound on the dynamic range accessible in a time-resolved experiment for a given bunch separation is calculated for a range of scintillators. New bunch structures are suggested for DLS and ESRF using the highest-performing commercially available crystal LYSO:Ce, allowing time-resolved experiments with an interframe time of 189 ns and a maximum dynamic range of 98 (6.6 bits)

  2. A new fixed-target approach for serial crystallography at synchrotron light sources and X-ray free electron lasers

    Energy Technology Data Exchange (ETDEWEB)

    Roedig, Philip

    2017-07-15

    In the framework of this thesis, a new method for high-speed fixed-target serial crystallography experiments and its applicability to biomacromolecular crystallography at both synchrotron light sources and X-ray free electron lasers (XFELs) is presented. The method is based on a sample holder, which can carry up to 20,000 microcrystals and which is made of single-crystalline silicon. Using synchrotron radiation, the structure of Operophtera brumata cytoplasmic polyhedrosis virus type 18 polyhedrin, lysozyme and cubic insulin was determined by collecting X-ray diffraction data from multiple microcrystals. Data collection was shown to be possible at both cryogenic and ambient conditions. For room-temperature measurements, both global and specific indications of radiation damage were investigated and characterized. Due to the sieve-like structure of the chip, the microcrystals tend to arrange themselves according to the micropore pattern, which allows for efficient sampling of the sample material. In combination with a high-speed scanning stage, the sample holder was furthermore shown to be highly suitable for serial femtosecond crystallography experiments. By fast raster scanning of the chip through the pulsed X-ray beam of an XFEL, structure determination of a virus, using the example of bovine enterovirus type 2, has been demonstrated at an XFEL for the first time. Hit rates of up to 100% were obtained by the presented method, which refers to a reduction in sample consumption by at least three orders of magnitude with respect to common liquid-jet injection methods used for sample delivery. In this way, the typical time needed for data collection in serial femtosecond crystallography is significantly decreased. The presented technique for sample loading of the chip is easy to learn and results in efficient removal of the surrounding mother liquor, thereby reducing the generated background signal. Since the chip is made of single-crystalline silicon, in principle no

  3. A new fixed-target approach for serial crystallography at synchrotron light sources and X-ray free electron lasers

    International Nuclear Information System (INIS)

    Roedig, Philip

    2017-07-01

    In the framework of this thesis, a new method for high-speed fixed-target serial crystallography experiments and its applicability to biomacromolecular crystallography at both synchrotron light sources and X-ray free electron lasers (XFELs) is presented. The method is based on a sample holder, which can carry up to 20,000 microcrystals and which is made of single-crystalline silicon. Using synchrotron radiation, the structure of Operophtera brumata cytoplasmic polyhedrosis virus type 18 polyhedrin, lysozyme and cubic insulin was determined by collecting X-ray diffraction data from multiple microcrystals. Data collection was shown to be possible at both cryogenic and ambient conditions. For room-temperature measurements, both global and specific indications of radiation damage were investigated and characterized. Due to the sieve-like structure of the chip, the microcrystals tend to arrange themselves according to the micropore pattern, which allows for efficient sampling of the sample material. In combination with a high-speed scanning stage, the sample holder was furthermore shown to be highly suitable for serial femtosecond crystallography experiments. By fast raster scanning of the chip through the pulsed X-ray beam of an XFEL, structure determination of a virus, using the example of bovine enterovirus type 2, has been demonstrated at an XFEL for the first time. Hit rates of up to 100% were obtained by the presented method, which refers to a reduction in sample consumption by at least three orders of magnitude with respect to common liquid-jet injection methods used for sample delivery. In this way, the typical time needed for data collection in serial femtosecond crystallography is significantly decreased. The presented technique for sample loading of the chip is easy to learn and results in efficient removal of the surrounding mother liquor, thereby reducing the generated background signal. Since the chip is made of single-crystalline silicon, in principle no

  4. PULSE GENERATOR

    Science.gov (United States)

    Roeschke, C.W.

    1957-09-24

    An improvement in pulse generators is described by which there are produced pulses of a duration from about 1 to 10 microseconds with a truly flat top and extremely rapid rise and fall. The pulses are produced by triggering from a separate input or by modifying the current to operate as a free-running pulse generator. In its broad aspect, the disclosed pulse generator comprises a first tube with an anode capacitor and grid circuit which controls the firing; a second tube series connected in the cathode circuit of the first tube such that discharge of the first tube places a voltage across it as the leading edge of the desired pulse; and an integrator circuit from the plate across the grid of the second tube to control the discharge time of the second tube, determining the pulse length.

  5. Generation of brain pseudo-CTs using an undersampled, single-acquisition UTE-mDixon pulse sequence and unsupervised clustering

    International Nuclear Information System (INIS)

    Su, Kuan-Hao; Hu, Lingzhi; Traughber, Melanie; Stehning, Christian; Helle, Michael; Qian, Pengjiang; Thompson, Cheryl L.; Pereira, Gisele C.; Traughber, Bryan J.; Jordan, David W.; Herrmann, Karin A.; Muzic, Raymond F.

    2015-01-01

    Purpose: MR-based pseudo-CT has an important role in MR-based radiation therapy planning and PET attenuation correction. The purpose of this study is to establish a clinically feasible approach, including image acquisition, correction, and CT formation, for pseudo-CT generation of the brain using a single-acquisition, undersampled ultrashort echo time (UTE)-mDixon pulse sequence. Methods: Nine patients were recruited for this study. For each patient, a 190-s, undersampled, single acquisition UTE-mDixon sequence of the brain was acquired (TE = 0.1, 1.5, and 2.8 ms). A novel method of retrospective trajectory correction of the free induction decay (FID) signal was performed based on point-spread functions of three external MR markers. Two-point Dixon images were reconstructed using the first and second echo data (TE = 1.5 and 2.8 ms). R2 ∗ images (1/T2 ∗ ) were then estimated and were used to provide bone information. Three image features, i.e., Dixon-fat, Dixon-water, and R2 ∗ , were used for unsupervised clustering. Five tissue clusters, i.e., air, brain, fat, fluid, and bone, were estimated using the fuzzy c-means (FCM) algorithm. A two-step, automatic tissue-assignment approach was proposed and designed according to the prior information of the given feature space. Pseudo-CTs were generated by a voxelwise linear combination of the membership functions of the FCM. A low-dose CT was acquired for each patient and was used as the gold standard for comparison. Results: The contrast and sharpness of the FID images were improved after trajectory correction was applied. The mean of the estimated trajectory delay was 0.774 μs (max: 1.350 μs; min: 0.180 μs). The FCM-estimated centroids of different tissue types showed a distinguishable pattern for different tissues, and significant differences were found between the centroid locations of different tissue types. Pseudo-CT can provide additional skull detail and has low bias and absolute error of estimated CT

  6. Generation of brain pseudo-CTs using an undersampled, single-acquisition UTE-mDixon pulse sequence and unsupervised clustering

    Energy Technology Data Exchange (ETDEWEB)

    Su, Kuan-Hao [Case Center for Imaging Research, Case Western Reserve University, Cleveland, Ohio 44106 and Department of Radiology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio 44106 (United States); Hu, Lingzhi; Traughber, Melanie [Philips Healthcare, Cleveland, Ohio 44143 (United States); Stehning, Christian; Helle, Michael [Philips Research, Hamburg 22335 (Germany); Qian, Pengjiang [School of Digital Media, Jiangnan University, Jiangsu 214122 (China); Thompson, Cheryl L. [Departments of Family Medicine and Community Health and Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio 44106 and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio 44106 (United States); Pereira, Gisele C.; Traughber, Bryan J., E-mail: bryan.traughber@case.edu [Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University, Cleveland, Ohio 44106 (United States); Jordan, David W. [Department of Radiology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio 44106 (United States); Herrmann, Karin A. [Department of Radiology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio 44106 and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio 44106 (United States); Muzic, Raymond F. [Case Center for Imaging Research, Case Western Reserve University, Cleveland, Ohio 44106 (United States); Department of Radiology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio 44106 (United States); Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106 (United States)

    2015-08-15

    Purpose: MR-based pseudo-CT has an important role in MR-based radiation therapy planning and PET attenuation correction. The purpose of this study is to establish a clinically feasible approach, including image acquisition, correction, and CT formation, for pseudo-CT generation of the brain using a single-acquisition, undersampled ultrashort echo time (UTE)-mDixon pulse sequence. Methods: Nine patients were recruited for this study. For each patient, a 190-s, undersampled, single acquisition UTE-mDixon sequence of the brain was acquired (TE = 0.1, 1.5, and 2.8 ms). A novel method of retrospective trajectory correction of the free induction decay (FID) signal was performed based on point-spread functions of three external MR markers. Two-point Dixon images were reconstructed using the first and second echo data (TE = 1.5 and 2.8 ms). R2{sup ∗} images (1/T2{sup ∗}) were then estimated and were used to provide bone information. Three image features, i.e., Dixon-fat, Dixon-water, and R2{sup ∗}, were used for unsupervised clustering. Five tissue clusters, i.e., air, brain, fat, fluid, and bone, were estimated using the fuzzy c-means (FCM) algorithm. A two-step, automatic tissue-assignment approach was proposed and designed according to the prior information of the given feature space. Pseudo-CTs were generated by a voxelwise linear combination of the membership functions of the FCM. A low-dose CT was acquired for each patient and was used as the gold standard for comparison. Results: The contrast and sharpness of the FID images were improved after trajectory correction was applied. The mean of the estimated trajectory delay was 0.774 μs (max: 1.350 μs; min: 0.180 μs). The FCM-estimated centroids of different tissue types showed a distinguishable pattern for different tissues, and significant differences were found between the centroid locations of different tissue types. Pseudo-CT can provide additional skull detail and has low bias and absolute error of

  7. Medical application of Synchrotron Radiation

    International Nuclear Information System (INIS)

    Hyodo, Kazuyuki; Nishimura, Katsuyuki.

    1990-01-01

    The number of patients suffering from ischemic heart disease is also increasing rapidly in Japan. The standard method for assessing coronary artery diseases is the coronary angiography. Excellent images are taken by this method, however, it is an invasive method in which a catheter into a peripheral artery. The patients would obtain great benefit if the coronary arteries could be distinguished by intravenous injection of the contrast material. The K-edge subtraction method, which uses the K-edge discontinuity in the attenuation coefficient of the contrast material, is considered to be the most suitable method for coronary angiography by peripheral venous injection. Synchrotron Radiation (SR) is so intense that it allows selection of monochromatic X-rays, and studies on K-edge subtraction using SR has been started at some facilities. Recent activities K-edge subtraction method at the Accumulation Ring are briefly described here. (author)

  8. Rapid cycling superconducting booster synchrotron

    International Nuclear Information System (INIS)

    Dinev, D.; Agapov, N.; Butenko, A.

    2001-01-01

    The existing set of Nuclotron heavy ion sources, such as duoplasmatron, polarized deuteron, laser and electron beam ion sources permits to have ion beams over a wide range of masses. The main problem for us now is to gain high intensity of accelerator particles. It can be solved by means of multiturn injection of the low current beams into the booster, acceleration up to the intermediate energies, stripping and transferring into the main ring. A design study of this accelerator - the 250 MeV/Amu Nuclotron booster synchrotron at 1 Hz repetition rate and circumference of 84 m, has been completed. The lattice dipole and quadrupole magnets have an iron yoke coils, made of hollow superconductor, are cooled by two-phase Helium flow, as well as the Nuclotron magnets. (authors)

  9. High heat load synchrotron optics

    International Nuclear Information System (INIS)

    Mills, D.M.

    1993-01-01

    Third generation synchrotron radiation sources currently being constructed worldwide will produce x-ray beams of unparalleled power and power density. These high heat fluxes coupled with the stringent dimensional requirements of the x-ray optical components pose a prodigious challenge to designers of x-ray optical elements, specifically x-ray mirrors and crystal monochromators. Although certain established techniques for the cooling of high heat flux components can be directly applied to this problem, the thermal management of high heat load x-ray optical components has several unusual aspects that may ultimately lead to unique solutions. This manuscript attempts to summarize the various approaches currently being applied to this undertaking and to point out the areas of research that require further development

  10. Synchrotron tomography on metallic foams

    International Nuclear Information System (INIS)

    Haibel, A.; Banhart, J.

    2003-01-01

    Metallic foams are a class of materials with unique properties. In contrast to most aqueous foams which are stable due to surface active agents, the liquid state of metallic foams can be stabilized by admixing small non-soluble particles. We present the results of our investigations on such materials consisting three different components: an aluminium alloy, silicon carbide particles for foam stabilization, and titanium hydride acting as blowing agent. By means of synchrotron-tomography we visualized the three dimensional distribution of the silicon carbide and the titanium hydride particles in the unfoamed cast solid precursor, in the fully foamed liquid state, and in the solidified final state of the foam. We analyzed the silicon carbide formation in these three foaming stages and its influence of the pore stability

  11. High-intensity laser synchrotron x-ray source

    International Nuclear Information System (INIS)

    Pogorelsky, I.V.

    1995-10-01

    A laser interacting with a relativistic electron beam behaves like a virtual wiggler of an extremely short period equal to half of the laser wavelength. This approach opens a route to relatively compact, high-brightness x-ray sources alternative or complementary to conventional synchrotron light sources. Although not new, the Laser Synchrotron Light Source (LSLS) concept is still waiting for a convincing demonstration. Available at the BNL's Accelerator Test Facility (ATF), a high-brightness electron beam and the high-power C0 2 laser may be used as prototype LSLS brick stones. In a feasible demonstration experiment, 10-GW, 100-ps C0 2 laser beam will be brought to a head-on collision with a 10-ps, 0.5-nC, 70 MeV electron bunch. Flashes of well-collimated, up to 9.36-keV (∼ Angstrom) x-rays of 10-ps pulse duration, with a flux of ∼10 19 photons/sec will be produced via linear Compton backscattering. The x-ray spectrum is tunable proportionally to a variable e-beam energy. A natural short-term extension of the proposed experiment would be further enhancement of the x-ray flux to a 10 21 -10 22 photons/sec level, after the ongoing ATF CO 2 laser upgrade to 1 TW peak power and electron bunch shortening to 3 ps. The ATF LSLS x-ray beamline, exceeding by orders of magnitude the peak fluxes attained at the National Synchrotron Light Source (NSLS) x-ray storage ring, may become attractive for certain users, e.g., for biological x-ray microscopy. In addition, a terawatt CO 2 laser will enable harmonic multiplication of the x-ray spectrum via nonlinear Compton scattering

  12. Characterization of Medipix3 With Synchrotron Radiation

    CERN Document Server

    Gimenez, E N; Marchal, J; Turecek, D; Ballabriga, R; Tartoni, N; Campbell, M; Llopart, X; Sawhney, K J S

    2011-01-01

    Medipix3 is the latest generation of photon counting readout chips of the Medipix family. With the same dimensions as Medipix2 (256 x 256 pixels of 55 mu m x 55 mu m pitch each), Medipix3 is however implemented in an 8-layer metallization 0.13 mu m CMOS technology which leads to an increase in the functionality associated with each pixel over Medipix2. One of the new operational modes implemented in the front-end architecture is the Charge Summing Mode (CSM). This mode consists of a charge reconstruction and hit allocation algorithm which eliminates event-by-event the low energy counts produced by charge-shared events between adjacent pixels. The present work focuses on the study of the CSM mode and compares it to the Single Pixel Mode (SPM) which is the conventional readout method for these kind of detectors and it is also implemented in Medipix3. Tests of a Medipix3 chip bump-bonded to a 300 mu m thick silicon photodiode sensor were performed at the Diamond Light Source synchrotron to evaluate the performan...

  13. Studying Magnetohydrodynamic Turbulence with Synchrotron Polarization Dispersion

    Science.gov (United States)

    Zhang, Jian-Fu; Lazarian, Alex; Lee, Hyeseung; Cho, Jungyeon

    2016-07-01

    We test a new technique for studying magnetohydrodynamic turbulence suggested by Lazarian & Pogosyan, using synthetic observations of synchrotron polarization. This paper focuses on a one-point statistics, which is termed polarization frequency analysis, that is characterized by the variance of polarized emission as a function of the square of the wavelength along a single line of sight. We adopt the ratio η of the standard deviation of the line-of-sight turbulent magnetic field to the line-of-sight mean magnetic field to depict the level of turbulence. When this ratio is large (η \\gg 1), which characterizes a region dominated by turbulent field, or small (η ≲ 0.2), which characterizes a region dominated by the mean field, we obtain the polarization variance \\propto {λ }-2 or \\propto {λ }-2-2m, respectively. At small η, I.e., in the region dominated by the mean field, we successfully recover the turbulent spectral index from the polarization variance. We find that our simulations agree well with the theoretical prediction of Lazarian & Pogosyan. With existing and upcoming data cubes from the Low-Frequency Array for Radio Astronomy (LOFAR) and the Square Kilometer Array (SKA), this new technique can be applied to study the magnetic turbulence in the Milky Way and other galaxies.

  14. Report of the Synchrotron Radiation Vacuum Workshop

    Energy Technology Data Exchange (ETDEWEB)

    Avery, R.T.

    1984-06-01

    The Synchrotron Radiation Vacuum Workshop was held to consider two vacuum-related problems that bear on the design of storage rings and beam lines for synchrotron radiation facilities. These problems are gas desorption from the vacuum chamber walls and carbon deposition on optical components. Participants surveyed existing knowledge on these topics and recommended studies that should be performed as soon as possible to provide more definitive experimental data on these topics. This data will permit optimization of the final design of the Advanced Light Source (ALS) and its associated beam lines. It also should prove useful for other synchrotron radiation facilities as well.

  15. Synchrotron power supply of TARN II

    International Nuclear Information System (INIS)

    Watanabe, Shin-ichi.

    1991-07-01

    The construction and performance of synchrotron power supply of TARN II are described. The 1.1 GeV synchrotron-cooler TARN II has been constructed at Institute for Nuclear Study, University of Tokyo. Constructed power supply for the dipole magnets is 600 V, 2500 A operated in the mode of trapezoid wave form with the repetition cycle of 0.1 Hz. The stability of magnetic field within 10 -3 and tracking error of 10 -4 have been attained with the aid of computer control system. First trial of synchrotron acceleration of He 2+ beam has been done up to 600 MeV in April, 1991. (author)

  16. Report of the Synchrotron Radiation Vacuum Workshop

    International Nuclear Information System (INIS)

    Avery, R.T.

    1984-06-01

    The Synchrotron Radiation Vacuum Workshop was held to consider two vacuum-related problems that bear on the design of storage rings and beam lines for synchrotron radiation facilities. These problems are gas desorption from the vacuum chamber walls and carbon deposition on optical components. Participants surveyed existing knowledge on these topics and recommended studies that should be performed as soon as possible to provide more definitive experimental data on these topics. This data will permit optimization of the final design of the Advanced Light Source (ALS) and its associated beam lines. It also should prove useful for other synchrotron radiation facilities as well

  17. Electric field detection of coherent synchrotron radiation in a storage ring generated using laser bunch slicing

    International Nuclear Information System (INIS)

    Katayama, I.; Shimosato, H.; Bito, M.; Furusawa, K.; Adachi, M.; Zen, H.; Kimura, S.; Katoh, M.; Shimada, M.; Yamamoto, N.; Hosaka, M.; Ashida, M.

    2012-01-01

    The electric field of coherent synchrotron radiation (CSR) generated by laser bunch slicing in a storage ring has been detected by an electro-optic sampling method. The gate pulses for sampling are sent through a large-mode-area photonic-crystal fiber. The observed electric field profile of the CSR is in good agreement with the spectrum of the CSR observed using Fourier transform far-infrared spectrometry, indicating good phase stability in the CSR. The longitudinal density profiles of electrons modulated by laser pulses were evaluated from the electric field profile.

  18. Electron multiplier as a detector for soft x rays from synchrotron and laser plasma sources

    Science.gov (United States)

    Buckley, Christopher J.; Dermody, Geraint; Khaleque, Naz I.; Michette, Alan G.; Pfauntsch, Slawka J.; Turcu, I. C. Edmond; Allott, Ric M.

    1998-11-01

    An electron-tubes-LTD 129EM electron multiplier tube has been modified to act as a detector of soft x-rays. the first dynode was coated with 100 nm of CsI and the assembly was mounted in a small vacuum chamber with 100 nm thick silicon nitride entrance window. Initial tests show the detector is linear up to an input flux of approximately 1MHz on a synchrotron source and has proved effective in providing pulse height discrimination when used on a pulsed laser plasma source.

  19. Activity report of Synchrotron Radiation Laboratory 2005

    International Nuclear Information System (INIS)

    2006-11-01

    Since 1980s, the Synchrotron Radiation Laboratory (SRL) has been promoting the 'Super-SOR' project, the new synchrotron radiation facility dedicated to sciences in vacuum ultraviolet and soft X-ray regions. The University of Tokyo considered the project as one of the most important future academic plans and strongly endorsed to construct the new facility with an electron storage ring of third generation type in the Kashiwa campus. During last year, the design of the accelerator system was slightly modified to obtain stronger support of the people in the field of bio-sciences, such as medicine, pharmacy, agriculture, etc. The energy of the storage ring was increased to 2.4 GeV, which is determined to obtain undulator radiation with sufficient brightness in X-ray region for the protein crystallography experiments. The value was also optimised to avoid considerable degradation of undulator radiation in the VUV and soft X-ray regions. However, in October last year, the president office of the University found out that the promotion of the project was very difficult for financial reasons. The budget for the new facility project is too big to be supported by a single university. The decision was intensively discussed by the International Review Committee on the Institute for Solid State Physics (ISSP), which was held at ISSP from November 14 to 16. The committee understood that the restructuring of the University system in Japan would overstrain the financial resources of the University of Tokyo and accepted the decision by the University. Presently, SRL has inclined to install beamlines using undulator radiation in other SR facilities instead of constructing a facility with a light source accelerator. At new beamlines, SRL will promote advanced materials sciences utilizing high brilliance and small emittance of synchrotron radiation which have been considered in the Super-SOR project. They are those such as microscopy and time-resolved experiments, which will only be

  20. Protein crystal structure from non-oriented, single-axis sparse X-ray data

    Directory of Open Access Journals (Sweden)

    Jennifer L. Wierman

    2016-01-01

    Full Text Available X-ray free-electron lasers (XFELs have inspired the development of serial femtosecond crystallography (SFX as a method to solve the structure of proteins. SFX datasets are collected from a sequence of protein microcrystals injected across ultrashort X-ray pulses. The idea behind SFX is that diffraction from the intense, ultrashort X-ray pulses leaves the crystal before the crystal is obliterated by the effects of the X-ray pulse. The success of SFX at XFELs has catalyzed interest in analogous experiments at synchrotron-radiation (SR sources, where data are collected from many small crystals and the ultrashort pulses are replaced by exposure times that are kept short enough to avoid significant crystal damage. The diffraction signal from each short exposure is so `sparse' in recorded photons that the process of recording the crystal intensity is itself a reconstruction problem. Using the EMC algorithm, a successful reconstruction is demonstrated here in a sparsity regime where there are no Bragg peaks that conventionally would serve to determine the orientation of the crystal in each exposure. In this proof-of-principle experiment, a hen egg-white lysozyme (HEWL crystal rotating about a single axis was illuminated by an X-ray beam from an X-ray generator to simulate the diffraction patterns of microcrystals from synchrotron radiation. Millions of these sparse frames, typically containing only ∼200 photons per frame, were recorded using a fast-framing detector. It is shown that reconstruction of three-dimensional diffraction intensity is possible using the EMC algorithm, even with these extremely sparse frames and without knowledge of the rotation angle. Further, the reconstructed intensity can be phased and refined to solve the protein structure using traditional crystallographic software. This suggests that synchrotron-based serial crystallography of micrometre-sized crystals can be practical with the aid of the EMC algorithm even in cases

  1. High density terahertz frequency comb produced by coherent synchrotron radiation

    Science.gov (United States)

    Tammaro, S.; Pirali, O.; Roy, P.; Lampin, J.-F.; Ducournau, G.; Cuisset, A.; Hindle, F.; Mouret, G.

    2015-07-01

    Frequency combs have enabled significant progress in frequency metrology and high-resolution spectroscopy extending the achievable resolution while increasing the signal-to-noise ratio. In its coherent mode, synchrotron radiation is accepted to provide an intense terahertz continuum covering a wide spectral range from about 0.1 to 1 THz. Using a dedicated heterodyne receiver, we reveal the purely discrete nature of this emission. A phase relationship between the light pulses leads to a powerful frequency comb spanning over one decade in frequency. The comb has a mode spacing of 846 kHz, a linewidth of about 200 Hz, a fractional precision of about 2 × 10-10 and no frequency offset. The unprecedented potential of the comb for high-resolution spectroscopy is demonstrated by the accurate determination of pure rotation transitions of acetonitrile.

  2. Arbitrary function generator for APS injector synchrotron correction magnets

    International Nuclear Information System (INIS)

    Despe, O.D.

    1991-01-01

    The APS injector synchrotron has eighty correction magnets around its circumference to provide the vernier field changes required for beam orbit correction during acceleration. The arbitrary function generator (AFG) design is based on scanning out encoded data from a semi-conductor memory, a first-in-first-out (FIFO) device. The data input consists of a maximum of 20 correction values specified within the acceleration window. Additional points between these values are then linearly interpolated to create a uniformly spaced 1000 data-point function stored in the FIFO. Each point, encoded as a 3-bit value is scanned out in synchronism with the injection pulse and used to clock the up/down counter driving the DAC. The DAC produces the analog reference voltage used to control the magnet current. 1 ref., 4 figs

  3. Beam loss control on the ISIS synchrotron simulations, measurements, upgrades

    CERN Document Server

    Warsop, C M

    2003-01-01

    The ISIS 800 MeV proton synchrotron presently provides 2.5*10/sup 13/ protons per pulse at 50 Hz, corresponding to a mean power of 160 kW. A dual harmonic RF system upgrade, now being installed, is expected to increase the intensity and power to about 3.75*10/sup 13/ ppp and 240 kW respectively. This paper describes work presently underway to understand and optimise beam loss control, which is a dominant factor determining operational performance. The main features of the collimation system are described, and Monte Carlo simulations of the loss control process are used to understand variations of efficiency with beam loss mode (growth rate, plane). Results of simulations are compared with measurements and operational data. Improvements to measurements are also outlined.

  4. A prototype chopper for synchrotron time-resolved crystallographic measurements

    International Nuclear Information System (INIS)

    Husheer, S. L. G.; Cole, J. M.; D'Almeida, T.; Teat, S. J.

    2010-01-01

    A mechanical x-ray chopper has been designed to perform microsecond time-resolved crystallographic studies at the DIAMOND synchrotron I19 beamline. It consists of two asymmetric absorbers rotating synchronously at frequencies from 0 to 50 Hz in the same direction around a rotation axis that is parallel to the x-ray beam. The duration of the x-ray pulses produced by the chopper is determined by the relative phase between the two blades, which can be adjusted. The chopper system presented in this paper offers a time resolution suitable for conducting in situ experiments that afford the crystal structure of materials while in their transient (>10 μs) photoactivated excited states.

  5. Spain in quandry over French synchrotron

    CERN Multimedia

    Bosch, X

    2000-01-01

    The French government has invited Spain to participate in the funding and operation of its proposed synchrotron Soleil. This could result though in the end of Spanish scientists' hopes for their own machine (1 page).

  6. National Synchrotron Light Source annual report 1988

    Energy Technology Data Exchange (ETDEWEB)

    Hulbert, S.; Lazarz, N.; Williams, G. (eds.)

    1988-01-01

    This report discusses the experiment done at the National Synchrotron Light Source. Most experiments discussed involves the use of the x-ray beams to study physical properties of solid materials. (LSP)

  7. Simulation of synchrotron motion with rf noise

    International Nuclear Information System (INIS)

    Leemann, B.T.; Forest, E.; Chattopadhyay, S.

    1986-08-01

    The theoretical formulation is described that is behind an algorithm for synchrotron phase-space tracking with rf noise and some preliminary simulation results of bunch diffusion under rf noise obtained by actual tracking

  8. Stanford Synchrotron Radiation Light Source (SSRL)

    Data.gov (United States)

    Federal Laboratory Consortium — The SSRL at SLAC National Accelerator Laboratory was built in 1974 to take and use for synchrotron studies the intense x-ray beams from the SPEAR storage ring that...

  9. Synchrotron X-ray magnetic scattering

    CERN Document Server

    Stirling, W G

    2003-01-01

    Research on magnetic materials constitutes an increasingly important part of the programmes of most major synchrotron radiation centres. The extremely high brilliance and small spot size of advanced synchrotron beamlines, combined with element-specific resonant effects at certain absorption edges, provide a powerful probe of magnetic structures and phase transitions, with excellent wavevector resolution. Over the last decade a variety of experimental techniques have been developed, exploiting these effects for the study of thin film, multilayer and bulk magnetic materials. In this paper the basic concepts of X-ray magnetic scattering will be introduced, followed by recent examples taken from work at Daresbury Laboratory (UK), the European Synchrotron Radiation Facility (Grenoble, France) and the National Synchrotron Light Source (Brookhaven National Laboratory, USA). Investigations of domain patterns in thin magnetic films employing X-ray resonant magnetic scattering (XRMS) will be described, followed by a se...

  10. Molecular photoemission studies using synchrotron radiation

    International Nuclear Information System (INIS)

    Truesdale, C.M.

    1983-04-01

    The angular distributions of photoelectrons and Auger electrons were measured by electron spectroscopy using synchrotron radiation. The experimental results are compared with theoretical calculations to interpret the electronic behavior of photoionization for molecular systems

  11. Applications of synchrotron radiation in Biophysics

    International Nuclear Information System (INIS)

    Bemski, G.

    1983-01-01

    A short introduction to the generation of the synchrotron radiation is made. Following, the applications of such a radiation in biophysics with emphasis to the study of the hemoglobin molecule are presented. (L.C.) [pt

  12. Synchrotron radiation applications in medical research

    Energy Technology Data Exchange (ETDEWEB)

    Thomlinson, W.

    1997-08-01

    Over the past two decades there has been a phenomenal growth in the number of dedicated synchrotron radiation facilities and a corresponding growth in the number of applications in both basic and applied sciences. The high flux and brightness, tunable beams, time structure and polarization of synchrotron radiation provide an ideal x- ray source for many applications in the medical sciences. There is a dual aspect to the field of medical applications of synchrotron radiation. First there are the important in-vitro programs such as structural biology, x-ray microscopy, and radiation cell biology. Second there are the programs that are ultimately targeted at in-vivo applications. The present status of synchrotron coronary angiography, bronchography, multiple energy computed tomography, mammography and radiation therapy programs at laboratories around the world is reviewed.

  13. Fiber structural analysis by synchrotron radiation

    CERN Document Server

    Kojima, J I; Kikutani, T

    2003-01-01

    Topics of fiber structural analysis by synchrotron radiation are explained. There are only three synchrotron radiation facilities in the world, SPring-8 (Super Photon ring-8) in Japan, APS (Advanced Photon Source) in U.S.A. and ESRF (European Synchrotron Radiation Facility) in France. Online measurement of melt spinning process of PET and Nylon6 is explained in detail. Polypropylene and PBO (poly-p-phenylenebenzobisoxazole) was measured by WAXD (Wide Angle X-ray Diffraction)/SAXS (Small Angle X-ray Scattering) at the same time. Some examples of measure of drawing process of fiber are described. The structure formation process of spider's thread was measured. Micro beam of X-ray of synchrotron facility was improved and it attained to 65nm small angle resolving power by 10 mu m beamsize. (S.Y.)

  14. National synchrotron light source VUV storage ring

    International Nuclear Information System (INIS)

    Blumberg, L.; Bittner, J.; Galayda, J.; Heese, R.; Krinsky, S.; Schuchman, J.; van Steenbergen, A.

    1979-01-01

    A 700 MeV electron storage ring designed for synchrotron radiation applications is described. Lattice and stability calculations are presented and the vacuum, correction and injection systems are discussed

  15. Probing droplets with biological colloidal suspensions on smart surfaces by synchrotron radiation micro- and nano-beams

    KAUST Repository

    Marinaro, Giovanni

    2015-03-01

    Droplets with colloidal biological suspensions evaporating on substrates with defined wetting properties generate confined environments for initiating aggregation and self-assembly processes. We describe smart micro- and nanostructured surfaces, optimized for probing single droplets and residues by synchrotron radiation micro- and nanobeam diffraction techniques. Applications are presented for Ac-IVD and β-amyloid (1-42) peptides capable of forming cross-β sheet structures. Complementary synchrotron radiation FTIR microspectroscopy addresses secondary structure formation. The high synchrotron radiation source brilliance enables fast raster-scan experiments. © 2015 Elsevier Ltd.

  16. Early British synchrotrons, an informal history

    International Nuclear Information System (INIS)

    Lawson, J.D.

    1997-02-01

    An historical account of the design and construction of early synchrotrons in the United Kingdom, based partly on personal reminiscences, is presented. Material is also drawn from archives at Birmingham and CERN. The document covers the period from plans for the world's first synchrotron at Malvern after the Second World War to work done at Harwell Laboratory for CERN in the period 1951-1953. (UK)

  17. Facilities for small-molecule crystallography at synchrotron sources.

    Science.gov (United States)

    Barnett, Sarah A; Nowell, Harriott; Warren, Mark R; Wilcox, Andrian; Allan, David R

    2016-01-01

    Although macromolecular crystallography is a widely supported technique at synchrotron radiation facilities throughout the world, there are, in comparison, only very few beamlines dedicated to small-molecule crystallography. This limited provision is despite the increasing demand for beamtime from the chemical crystallography community and the ever greater overlap between systems that can be classed as either small macromolecules or large small molecules. In this article, a very brief overview of beamlines that support small-molecule single-crystal diffraction techniques will be given along with a more detailed description of beamline I19, a dedicated facility for small-molecule crystallography at Diamond Light Source.

  18. Synchrotron radiation from spherically accreting black holes

    International Nuclear Information System (INIS)

    Ipser, J.R.; Price, R.H.

    1982-01-01

    Spherical accretion onto a Schwartzchild black hole, of gas with frozen-in magnetic field, is studied numerically and analytically for a range of hole masses and accretion rates in which synchrotron emission is the dominant radiative mechanism. At small radii the equipartition of magnetic, kinetic, and gravitational energy is assumed to apply, and the gas is heated by dissipation of infalling magnetic energy, turbulent energy, etc. The models can be classified into three types: (a) synchrotron cooling negligible, (b) synchrotron cooling important but synchrotron self-absorption negligible, (c) synchrotron cooling and self-absorption important. In the first case gas temperatures become very high near the horizon but luminosity efficiencies (luminosity/mass-energy accretion rate) are low. In cases (b) and (c) the gas flow near the horizon is essentially isothermal and luminosity efficiencies are fairly high. The analysis and results for the isothermal cases (b) and (c) are valid only for moderate dissipative heating and synchrotron self-absorption. If self-absorption is very strong or if dissipated energy is comparable to infall energy, Comptonization effects, not included in the analysis, become important

  19. Pulse Oximetry

    Science.gov (United States)

    ... American Thoracic Society www. thoracic. org American Thoracic Society PATIENT EDUCATION | INFORMATION SERIES How accurate is the pulse oximeter? The ... patient. co. uk/ doctor/ Pulse- Oximetry. htm This ... service of the American Thoracic Society. The content is for educational purposes only. It ...

  20. Starting up the Saturne synchrotron

    International Nuclear Information System (INIS)

    Salvat, M.

    1958-02-01

    Illustrated by many drawings and graphs, this report describes and comments all operations and measurements to be performed for starting up the Saturne synchrotron until particle acceleration exclusively. The author reports the study of beam as it goes out of the Van de Graaff: experiment of position and stability of the beam axis, study of beam current and geometric characteristics (calibration of the induction probe), experiment of mass separation and proton percentage, and adjustment of regulation and Van de Graaff fall law. In a second part, he reports the optics alignment and the study of optics property (installation of the different sectors, study of inflector end voltage, and influence of inflector position in the chamber). The third part addresses the examination of phenomena associated with injection: injection method and definition of the initial instant, search for injection optimum conditions, study of particle lifetime and of phenomena on the inner probe. The fourth part proposes theoretical additional elements regarding the movement of particles at the injection in the useful area, and phenomena occurring on targets and on the inner probe