On-demand generation of background-free single photons from a solid-state source

Science.gov (United States)

Schweickert, Lucas; Jöns, Klaus D.; Zeuner, Katharina D.; Covre da Silva, Saimon Filipe; Huang, Huiying; Lettner, Thomas; Reindl, Marcus; Zichi, Julien; Trotta, Rinaldo; Rastelli, Armando; Zwiller, Val

2018-02-01

True on-demand high-repetition-rate single-photon sources are highly sought after for quantum information processing applications. However, any coherently driven two-level quantum system suffers from a finite re-excitation probability under pulsed excitation, causing undesirable multi-photon emission. Here, we present a solid-state source of on-demand single photons yielding a raw second-order coherence of g(2 )(0 )=(7.5 ±1.6 )×10-5 without any background subtraction or data processing. To this date, this is the lowest value of g(2 )(0 ) reported for any single-photon source even compared to the previously reported best background subtracted values. We achieve this result on GaAs/AlGaAs quantum dots embedded in a low-Q planar cavity by employing (i) a two-photon excitation process and (ii) a filtering and detection setup featuring two superconducting single-photon detectors with ultralow dark-count rates of (0.0056 ±0.0007 ) s-1 and (0.017 ±0.001 ) s-1, respectively. Re-excitation processes are dramatically suppressed by (i), while (ii) removes false coincidences resulting in a negligibly low noise floor.

[Quantitative image of bone mineral content--dual energy subtraction in a single exposure].

Science.gov (United States)

Katoh, T

1990-09-25

A dual energy subtraction system was constructed on an experimental basis for the quantitative image of bone mineral content. The system consists of a radiography system and an image processor. Two radiograms were taken with dual x-ray energy in a single exposure using an x-ray beam dichromized by a tin filter. In this system, a film cassette was used where a low speed film-screen system, a copper filter and a high speed film-screen system were layered on top of each other. The images were read by a microdensitometer and processed by a personal computer. The image processing included the corrections of the film characteristics and heterogeneity in the x-ray field, and the dual energy subtraction in which the effect of the high energy component of the dichromized beam on the tube side image was corrected. In order to determine the accuracy of the system, experiments using wedge phantoms made of mixtures of epoxy resin and bone mineral-equivalent materials in various fractions were performed for various tube potentials and film processing conditions. The results indicated that the relative precision of the system was within +/- 4% and that the propagation of the film noise was within +/- 11 mg/cm2 for the 0.2 mm pixels. The results also indicated that the system response was independent of the tube potential and the film processing condition. The bone mineral weight in each phalanx of the freshly dissected hand of a rhesus monkey was measured by this system and compared with the ash weight. The results showed an error of +/- 10%, slightly larger than that of phantom experiments, which is probably due to the effect of fat and the variation of focus-object distance. The air kerma in free air at the object was approximately 0.5 mGy for one exposure. The results indicate that this system is applicable to clinical use and provides useful information for evaluating a time-course of localized bone disease.

Hybrid intravenous digital subtraction angiography of the carotid bifurcation

International Nuclear Information System (INIS)

Burbank, F.H.; Enzmann, D.; Keyes, G.S.; Brody, W.R.

1984-01-01

A hybrid digital subtraction angiography technique and noise-reduction algorithm were used to evaluate the carotid bifurcation. Temporal, hybrid, and reduced-noise hybrid images were obtained in right and left anterior oblique projections, and both single- and multiple-frame images were created with each method. The resulting images were graded on a scale of 1 to 5 by three experienced neuroradiologists. Temporal images were preferred over hybrid images. The percentage of nondiagnostic examinations, as agreed upon by two readers, was higher for temporal alone than temporal + hybrid. In addition, also by agreement between two readers, temporal + hybrid images significantly increased the number of bifurcations seen in two views (87%) compared to temporal subtraction alone

NNLO jet cross sections by subtraction

International Nuclear Information System (INIS)

Somogyi, G.; Bolzoni, P.; Trocsanyi, Z.

2010-06-01

We report on the computation of a class of integrals that appear when integrating the so-called iterated singly-unresolved approximate cross section of an earlier NNLO subtraction scheme over the factorised phase space of unresolved partons. The integrated approximate cross section itself can be written as the product of an insertion operator (in colour space) times the Born cross section. We give selected results for the insertion operator for processes with two and three hard partons in the final state. (orig.)

NNLO jet cross sections by subtraction

Energy Technology Data Exchange (ETDEWEB)

Somogyi, G.; Bolzoni, P. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Trocsanyi, Z. [CERN, Geneva (Switzerland)

2010-06-15

We report on the computation of a class of integrals that appear when integrating the so-called iterated singly-unresolved approximate cross section of an earlier NNLO subtraction scheme over the factorised phase space of unresolved partons. The integrated approximate cross section itself can be written as the product of an insertion operator (in colour space) times the Born cross section. We give selected results for the insertion operator for processes with two and three hard partons in the final state. (orig.)

NNLO jet cross sections by subtraction

CERN Document Server

Somogyi, Gabor; Trocsanyi, Zoltan

2010-01-01

We report on the computation of a class of integrals that appear when integrating the so-called iterated singly-unresolved approximate cross section of the NNLO subtraction scheme of [1-4], over the factorised phase space of unresolved partons. The integrated approximate cross section itself can be written as the product of an insertion operator (in colour space) times the Born cross section. We give selected results for the insertion operator for processes with two and three hard partons in the final state.

X-ray image subtracting system

International Nuclear Information System (INIS)

Wesbey, W.H.; Keyes, G.S.; Georges, J.-P.J.

1982-01-01

An X-ray image subtracting system for making low contrast structures in the images more conspicuous is described. An X-ray source projects successive high and low energy X-ray beam pulses through a body and the resultant X-ray images are converted to optical images. Two image pick-up devices such as TV cameras that have synchronously operated shutters receive the alternate images and convert them to corresponding analog video signals. In some embodiments, the analog signals are converted to a matrix of digital pixel signals that are variously processed and subtracted and converted to signals for driving a TV monitor display and analog storage devices. In other embodiments the signals are processed and subtracted in analog form for display. The high and low energy pulses can follow each other immediately so good registration between subtracted images is obtainable even though the anatomy is in motion. The energy levels of the X-ray pulses are chosen to maximize the difference in attenuation between the anatomical structure which is to be subtracted out and that which remains. (author)

Temporal subtraction of dual-energy chest radiographs

International Nuclear Information System (INIS)

Armato, Samuel G. III; Doshi, Devang J.; Engelmann, Roger; Caligiuri, Philip; MacMahon, Heber

2006-01-01

Temporal subtraction and dual-energy imaging are two enhanced radiography techniques that are receiving increased attention in chest radiography. Temporal subtraction is an image processing technique that facilitates the visualization of pathologic change across serial chest radiographic images acquired from the same patient; dual-energy imaging exploits the differential relative attenuation of x-ray photons exhibited by soft-tissue and bony structures at different x-ray energies to generate a pair of images that accentuate those structures. Although temporal subtraction images provide a powerful mechanism for enhancing visualization of subtle change, misregistration artifacts in these images can mimic or obscure abnormalities. The purpose of this study was to evaluate whether dual-energy imaging could improve the quality of temporal subtraction images. Temporal subtraction images were generated from 100 pairs of temporally sequential standard radiographic chest images and from the corresponding 100 pairs of dual-energy, soft-tissue radiographic images. The registration accuracy demonstrated in the resulting temporal subtraction images was evaluated subjectively by two radiologists. The registration accuracy of the soft-tissue-based temporal subtraction images was rated superior to that of the conventional temporal subtraction images. Registration accuracy also was evaluated objectively through an automated method, which achieved an area-under-the-ROC-curve value of 0.92 in the distinction between temporal subtraction images that demonstrated clinically acceptable and clinically unacceptable registration accuracy. By combining dual-energy soft-tissue images with temporal subtraction, misregistration artifacts can be reduced and superior image quality can be obtained

Digital subtraction angiography of the heart and lungs

International Nuclear Information System (INIS)

Moodie, D.S.; Yiannikas, J.

1986-01-01

This book contains 12 chapters. Some of the chapter titles are: Physical Principles of Cardiac Digital Subtraction Angiography, The Use of Intravenous Digital Subtraction Angiography in Evaluating Patients with Complex Congenital Heart Disease, Exercise Intravenous Digital Subtraction Angiograpny, Cardiomyopathic and Cardiac Neoplastic Disease, Digital Subtraction Angiography in the Catheterization Laboratory, and Cardiac Digital Subtraction Angiography - Future Directions

Two-dimensional real-time imaging system for subtraction angiography using an iodine filter

Science.gov (United States)

Umetani, Keiji; Ueda, Ken; Takeda, Tohoru; Anno, Izumi; Itai, Yuji; Akisada, Masayoshi; Nakajima, Teiichi

1992-01-01

A new type of subtraction imaging system was developed using an iodine filter and a single-energy broad bandwidth monochromatized x ray. The x-ray images of coronary arteries made after intravenous injection of a contrast agent are enhanced by an energy-subtraction technique. Filter chopping of the x-ray beam switches energies rapidly, so that a nearly simultaneous pair of filtered and nonfiltered images can be made. By using a high-speed video camera, a pair of two 512 × 512 pixel images can be obtained within 9 ms. Three hundred eighty-four images (raw data) are stored in a 144-Mbyte frame memory. After phantom studies, in vivo subtracted images of coronary arteries in dogs were obtained at a rate of 15 images/s.

Subtraction MR venography acquired from time-resolved contrast-enhanced MR angiography: Comparison with phase-contrast MR venography and single-phase contrast-enhanced MR venography

International Nuclear Information System (INIS)

Jang, Jin Hee; Kim, Bum Soo; KIm, Bom Yi; Choi, Hyun Seok; Jung, So Lyung; Ahn, Kook Jin; Sung, Ji Kyeong

2015-01-01

To evaluate the image characteristics of subtraction magnetic resonance venography (SMRV) from time-resolved contrast-enhanced MR angiography (TRMRA) compared with phase-contrast MR venography (PCMRV) and single-phase contrast-enhanced MR venography (CEMRV). Twenty-one patients who underwent brain MR venography (MRV) using standard protocols (PCMRV, CEMRV, and TRMRA) were included. SMRV was made by subtracting the arterial phase data from the venous phase data in TRMRA. Co-registration and subtraction of the two volume data was done using commercially available software. Image quality and the degree of arterial contamination of the three MRVs were compared. In the three MRVs, 19 pre-defined venous structures (14 dural sinuses and 5 cerebral veins) were evaluated. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the three MRVs were also compared. Single-phase contrast-enhanced MR venography showed better image quality (median score 4 in both reviewers) than did the other two MRVs (p < 0.001), whereas SMRV (median score 3 in both reviewers) and PCMRV (median score 3 in both reviewers) had similar image quality (p ≥ 0.951). SMRV (median score 0 in both reviewers) suppressed arterial signal better than did the other MRVs (median score 1 in CEMRV, median score 2 in PCMRV, both reviewers) (p < 0.001). The dural sinus score of SMRV (median and interquartile range [IQR] 48, 43-50 for reviewer 1, 47, 43-49 for reviewer 2) was significantly higher than for PCMRV (median and IQR 31, 25-34 for reviewer 1, 30, 23-32 for reviewer 2) (p < 0.01) and did not differ from that of CEMRV (median and IQR 50, 47-52 for reviewer 1, 49, 45-51 for reviewer 2) (p = 0.146 in reviewer 1 and 0.123 in reviewer 2). The SNR and CNR of SMRV (median and IQR 104.5, 83.1-121.2 and 104.1, 74.9-120.5, respectively) were between those of CEMRV (median and IQR 150.3, 111-182.6 and 148.4, 108-178.2) and PCMRV (median and IQR 59.4, 49.2-74.9 and 53.6, 43.8-69.2). Subtraction magnetic

Background subtraction theory and practice

CERN Document Server

Elgammal, Ahmed

2014-01-01

Background subtraction is a widely used concept for detection of moving objects in videos. In the last two decades there has been a lot of development in designing algorithms for background subtraction, as well as wide use of these algorithms in various important applications, such as visual surveillance, sports video analysis, motion capture, etc. Various statistical approaches have been proposed to model scene backgrounds. The concept of background subtraction also has been extended to detect objects from videos captured from moving cameras. This book reviews the concept and practice of back

A subtraction scheme for computing QCD jet cross sections at NNLO: integrating the subtraction terms I

Science.gov (United States)

Somogyi, Gábor; Trócsányi, Zoltán

2008-08-01

In previous articles we outlined a subtraction scheme for regularizing doubly-real emission and real-virtual emission in next-to-next-to-leading order (NNLO) calculations of jet cross sections in electron-positron annihilation. In order to find the NNLO correction these subtraction terms have to be integrated over the factorized unresolved phase space and combined with the two-loop corrections. In this paper we perform the integration of all one-parton unresolved subtraction terms.

[Construction of fetal mesenchymal stem cell cDNA subtractive library].

Science.gov (United States)

Yang, Li; Wang, Dong-Mei; Li, Liang; Bai, Ci-Xian; Cao, Hua; Li, Ting-Yu; Pei, Xue-Tao

2002-04-01

To identify differentially expressed genes between fetal mesenchymal stem cell (MSC) and adult MSC, especially specified genes expressed in fetal MSC, a cDNA subtractive library of fetal MSC was constructed using suppression subtractive hybridization (SSH) technique. At first, total RNA was isolated from fetal and adult MSC. Using SMART PCR synthesis method, single-strand and double-strand cDNAs were synthesized. After Rsa I digestion, fetal MSC cDNAs were divided into two groups and ligated to adaptor 1 and adaptor 2 respectively. Results showed that the amplified library contains 890 clones. Analysis of 890 clones with PCR demonstrated that 768 clones were positive. The positive rate is 86.3%. The size of inserted fragments in these positive clones was between 0.2 - 1 kb, with an average of 400 - 600 bp. SSH is a convenient and effective method for screening differentially expressed genes. The constructed cDNA subtractive library of fetal MSC cDNA lays solid foundation for screening and cloning new and specific function related genes of fetal MSC.

Development of a Single-Step Subtraction Method for Eukaryotic 18S and 28S Ribonucleic Acids

Directory of Open Access Journals (Sweden)

Marie J. Archer

2011-01-01

Full Text Available The abundance of mammalian 18S and 28S ribosomal RNA can decrease the detection sensitivity of bacterial or viral targets in complex host-pathogen mixtures. A method to capture human RNA in a single step was developed and characterized to address this issue. For this purpose, capture probes were covalently attached to magnetic microbeads using a dendrimer linker and the solid phase was tested using rat thymus RNA (mammalian components with Escherichia coli RNA (bacterial target as a model system. Our results indicated that random capture probes demonstrated better performance than specific ones presumably by increasing the number of possible binding sites, and the use of a tetrame-thylammonium-chloride (TMA-Cl- based buffer for the hybridization showed a beneficial effect in the selectivity. The subtraction efficiency determined through real-time RT-PCR revealed capture-efficiencies comparable with commercially available enrichment kits. The performance of the solid phase can be further fine tuned by modifying the annealing time and temperature.

Removal of arterial wall calcifications in CT angiography by local subtraction

International Nuclear Information System (INIS)

Straten, Marcel van; Venema, Henk W.; Streekstra, Geert J.; Reekers, Jim A.; Heeten, Gerard J. den; Grimbergen, Cornelis A.

2003-01-01

CT Angiography (CTA) is an established technique for the minimally invasive imaging of arteries. The technique of maximum intensity projection (MIP) is often used to get a comprehensive overview of the vascular anatomy. On a MIP, however, arterial wall calcifications may hinder the visualization of the arterial lumen. These calcifications are in direct contact with the contrast-enhanced blood, which makes removal difficult. We present a local subtraction method for the automatic removal of these calcifications. In our approach a second CT scan has to be made, prior to contrast injection. The calcifications in both scans are registered prior to subtraction to compensate for displacements in between the two scans. Local subtraction results are compared with results obtained by thresholding. The method was tested in a phantom and with data from four patients. The phantom represented an artery with different types of stenosis. Data were used from patients for which CTA of the renal arteries was performed. For two patients the electrocardiogram (ECG) was recorded during the CTA examination, making retrospective cardiac gated reconstructions possible. Both the phantom and the patient study showed that the local subtraction method is capable of removing calcifications and visualizing the residual lumen. In the patient study it appeared that some artifacts remained for higher pitch values. We conclude that the local subtraction method is less subjective and more accurate than thresholding. Best results are obtained by use of a small pitch, at the expense of the volume covered during a single breath hold

Addition Table of Colours: Additive and Subtractive Mixtures Described Using a Single Reasoning Model

Science.gov (United States)

Mota, A. R.; Lopes dos Santos, J. M. B.

2014-01-01

Students' misconceptions concerning colour phenomena and the apparent complexity of the underlying concepts--due to the different domains of knowledge involved--make its teaching very difficult. We have developed and tested a teaching device, the addition table of colours (ATC), that encompasses additive and subtractive mixtures in a single…

Digital subtraction angiography for breast cancer

International Nuclear Information System (INIS)

Tsurumi, Kiyohiko; Okuyama, Nobuo

1987-01-01

We performed digital subtraction angiography (DSA) on 42 patients with breast diseases to investigate its efficiency. As a result we came to the following conclusions: 1. The sensitivity was well evaluated in intraarterial digital subtraction angiography (IA-DSA) of breast. 2. IA-DSA could diagnose difficult cases like cancer which had undergone augmentation mammoplasty, or like Paget's disease and others. 3. DSA was a safe examination method. 4. The sensitivity of IA-DSA of breast cancer is superior to intravenous digital subtraction angiography (IV-DSA). (author)

Identification of proteins involved in the functioning of Riftia pachyptila symbiosis by Subtractive Suppression Hybridization.

Science.gov (United States)

Sanchez, Sophie; Hourdez, Stéphane; Lallier, François H

2007-09-24

Since its discovery around deep sea hydrothermal vents of the Galapagos Rift about 30 years ago, the chemoautotrophic symbiosis between the vestimentiferan tubeworm Riftia pachyptila and its symbiotic sulfide-oxidizing gamma-proteobacteria has been extensively studied. However, studies on the tubeworm host were essentially targeted, biochemical approaches. We decided to use a global molecular approach to identify new proteins involved in metabolite exchanges and assimilation by the host. We used a Subtractive Suppression Hybridization approach (SSH) in an unusual way, by comparing pairs of tissues from a single individual. We chose to identify the sequences preferentially expressed in the branchial plume tissue (the only organ in contact with the sea water) and in the trophosome (the organ housing the symbiotic bacteria) using the body wall as a reference tissue because it is supposedly not involved in metabolite exchanges in this species. We produced four cDNA libraries: i) body wall-subtracted branchial plume library (BR-BW), ii) and its reverse library, branchial plume-subtracted body wall library (BW-BR), iii) body wall-subtracted trophosome library (TR-BW), iv) and its reverse library, trophosome-subtracted body wall library (BW-TR). For each library, we sequenced about 200 clones resulting in 45 different sequences on average in each library (58 and 59 cDNAs for BR-BW and TR-BW libraries respectively). Overall, half of the contigs matched records found in the databases with good E-values. After quantitative PCR analysis, it resulted that 16S, Major Vault Protein, carbonic anhydrase (RpCAbr), cathepsin and chitinase precursor transcripts were highly represented in the branchial plume tissue compared to the trophosome and the body wall tissues, whereas carbonic anhydrase (RpCAtr), myohemerythrin, a putative T-Cell receptor and one non identified transcript were highly specific of the trophosome tissue. Quantitative PCR analyses were congruent with our libraries

Identification of proteins involved in the functioning of Riftia pachyptila symbiosis by Subtractive Suppression Hybridization

Directory of Open Access Journals (Sweden)

Lallier François H

2007-09-01

Full Text Available Abstract Background Since its discovery around deep sea hydrothermal vents of the Galapagos Rift about 30 years ago, the chemoautotrophic symbiosis between the vestimentiferan tubeworm Riftia pachyptila and its symbiotic sulfide-oxidizing γ-proteobacteria has been extensively studied. However, studies on the tubeworm host were essentially targeted, biochemical approaches. We decided to use a global molecular approach to identify new proteins involved in metabolite exchanges and assimilation by the host. We used a Subtractive Suppression Hybridization approach (SSH in an unusual way, by comparing pairs of tissues from a single individual. We chose to identify the sequences preferentially expressed in the branchial plume tissue (the only organ in contact with the sea water and in the trophosome (the organ housing the symbiotic bacteria using the body wall as a reference tissue because it is supposedly not involved in metabolite exchanges in this species. Results We produced four cDNA libraries: i body wall-subtracted branchial plume library (BR-BW, ii and its reverse library, branchial plume-subtracted body wall library (BW-BR, iii body wall-subtracted trophosome library (TR-BW, iv and its reverse library, trophosome-subtracted body wall library (BW-TR. For each library, we sequenced about 200 clones resulting in 45 different sequences on average in each library (58 and 59 cDNAs for BR-BW and TR-BW libraries respectively. Overall, half of the contigs matched records found in the databases with good E-values. After quantitative PCR analysis, it resulted that 16S, Major Vault Protein, carbonic anhydrase (RpCAbr, cathepsin and chitinase precursor transcripts were highly represented in the branchial plume tissue compared to the trophosome and the body wall tissues, whereas carbonic anhydrase (RpCAtr, myohemerythrin, a putative T-Cell receptor and one non identified transcript were highly specific of the trophosome tissue. Conclusion Quantitative PCR

Bone images from dual-energy subtraction chest radiography in the detection of rib fractures.

Science.gov (United States)

Szucs-Farkas, Zsolt; Lautenschlager, Katrin; Flach, Patricia M; Ott, Daniel; Strautz, Tamara; Vock, Peter; Ruder, Thomas D

2011-08-01

To assess the sensitivity and image quality of chest radiography (CXR) with or without dual-energy subtracted (ES) bone images in the detection of rib fractures. In this retrospective study, 39 patients with 204 rib fractures and 24 subjects with no fractures were examined with a single exposure dual-energy subtraction digital radiography system. Three blinded readers first evaluated the non-subtracted posteroanterior and lateral chest radiographs alone, and 3 months later they evaluated the non-subtracted images together with the subtracted posteroanterior bone images. The locations of rib fractures were registered with confidence levels on a 3-grade scale. Image quality was rated on a 5-point scale. Marks by readers were compared with fracture localizations in CT as a standard of reference. The sensivity for fracture detection using both methods was very similar (34.3% with standard CXR and 33.5% with ES-CXR, p=0.92). At the patient level, both sensitivity (71.8%) and specificity (92.9%) with or without ES were identical. Diagnostic confidence was not significantly different (2.61 with CXR and 2.75 with ES-CXR, p=0.063). Image quality with ES was rated higher than that on standard CXR (4.08 vs. 3.74, prib fractures. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

Digital subtraction angiography in ischemic cerebrovascular accidents

Energy Technology Data Exchange (ETDEWEB)

Manelfe, C.; Bonafe, A.; Ducos de Lahitte, M.; Rascol, A.; Prere, J.; Guiraud, B.; Marc-Vergnes, J.P. (Hopital Purpan, 31 - Toulouse (France))

1983-12-29

Recent advances in computer and radiological technology have permitted reassessment of intravenous angiography in the evaluation of cerebrovascular disorders. Although digital subtraction angiography is a relatively new technique, it has rapidly gained a widespread acceptance. It has extended the use of angiography to outpatients and to people in whom conventional angiography is contraindicated. This reliable, safe, and relatively noninvasive technique offers the user two benefits: real-time subtraction and enhanced image quality. The system allows angiographic evaluation of the extracranial and intracranial vessels by means of intravenous injection of contrast material. Extracranial studies clearly demonstrate stenoses and occlusions of the major cervicocephalic arteries. Intracranial studies usually detect major cerebrovascular occlusions and provide insight into the collateral flow patterns. Intravenous digital subtraction angiography permits accurate assessment of cervicocephalic vessels after surgical repair. Although intravenous digital subtraction angiography obviates the need for conventional angiography in many cases, movements from the patients, or superimposition of vascular structures can substantially degrade the quality of the images. Digital subtraction angiography with intra-arterial injection of contrast medium will be contemplated in patients with poor intravenous digital subtraction angiography studies prior to surgery.

Digital subtraction angiography in ischemic cerebrovascular accidents

International Nuclear Information System (INIS)

Manelfe, C.; Bonafe, A.; Ducos de Lahitte, M.; Rascol, A.; Prere, J.; Guiraud, B.; Marc-Vergnes, J.P.

1983-01-01

Recent advances in computer and radiological technology have permitted reassessment of intravenous angiography in the evaluation of cerebrovascular disorders. Although digital subtraction angiography is a relatively new technique, it has rapidly gained a widespread acceptance. It has extended the use of angiography to outpatients and to people in whom conventional angiography is contraindicated. This reliable, safe, and relatively noninvasive technique offers the user two benefits: real-time subtraction and enhanced image quality. The system allows angiographic evaluation of the extracranial and intracranial vessels by means of intravenous injection of contrast material. Extracranial studies clearly demonstrate stenoses and occlusions of the major cervicocephalic arteries. Intracranial studies usually detect major cerebrovascular occlusions and provide insight into the collateral flow patterns. Intravenous digital subtraction angiography permits accurate assessment of cervicocephalic vessels after surgical repair. Although intravenous digital subtraction angiography obviates the need for conventional angiography in many cases, movements from the patients, or superimposition of vascular structures can substantially degrade the quality of the images. Digital subtraction angiography with intra-arterial injection of contrast medium will be contemplated in patients with poor intravenous digital subtraction angiography studies prior to surgery [fr

Photon Subtraction by Many-Body Decoherence

DEFF Research Database (Denmark)

Murray, C. R.; Mirgorodskiy, I.; Tresp, C.

2018-01-01

We experimentally and theoretically investigate the scattering of a photonic quantum field from another stored in a strongly interacting atomic Rydberg ensemble. Considering the many-body limit of this problem, we derive an exact solution to the scattering-induced spatial decoherence of multiple...... stored photons, allowing for a rigorous understanding of the underlying dissipative quantum dynamics. Combined with our experiments, this analysis reveals a correlated coherence-protection process in which the scattering from one excitation can shield all others from spatial decoherence. We discuss how...... this effect can be used to manipulate light at the quantum level, providing a robust mechanism for single-photon subtraction, and experimentally demonstrate this capability....

Analytical optimization of digital subtraction mammography with contrast medium using a commercial unit.

Science.gov (United States)

Rosado-Méndez, I; Palma, B A; Brandan, M E

2008-12-01

Contrast-medium-enhanced digital mammography (CEDM) is an image subtraction technique which might help unmasking lesions embedded in very dense breasts. Previous works have stated the feasibility of CEDM and the imperative need of radiological optimization. This work presents an extension of a former analytical formalism to predict contrast-to-noise ratio (CNR) in subtracted mammograms. The goal is to optimize radiological parameters available in a clinical mammographic unit (x-ray tube anode/filter combination, voltage, and loading) by maximizing CNR and minimizing total mean glandular dose (D(gT)), simulating the experimental application of an iodine-based contrast medium and the image subtraction under dual-energy nontemporal, and single- or dual-energy temporal modalities. Total breast-entrance air kerma is limited to a fixed 8.76 mGy (1 R, similar to screening studies). Mathematical expressions obtained from the formalism are evaluated using computed mammographic x-ray spectra attenuated by an adipose/glandular breast containing an elongated structure filled with an iodinated solution in various concentrations. A systematic study of contrast, its associated variance, and CNR for different spectral combinations is performed, concluding in the proposal of optimum x-ray spectra. The linearity between contrast in subtracted images and iodine mass thickness is proven, including the determination of iodine visualization limits based on Rose's detection criterion. Finally, total breast-entrance air kerma is distributed between both images in various proportions in order to maximize the figure of merit CNR2/D(gT). Predicted results indicate the advantage of temporal subtraction (either single- or dual-energy modalities) with optimum parameters corresponding to high-voltage, strongly hardened Rh/Rh spectra. For temporal techniques, CNR was found to depend mostly on the energy of the iodinated image, and thus reduction in D(gT) could be achieved if the spectral energy

BPHZL-subtraction scheme and axial gauges

Energy Technology Data Exchange (ETDEWEB)

Kreuzer, M.; Rebhan, A.; Schweda, M.; Piguet, O.

1986-03-27

The application of the BPHZL subtraction scheme to Yang-Mills theories in axial gauges is presented. In the auxillary mass formulation we show the validity of the convergence theorems for subtracted momentum space integrals, and we give the integral formulae necessary for one-loop calculations. (orig.).

Subtracted versus non-subtracted digital imaging in peripheral angiography

International Nuclear Information System (INIS)

Fink, U.; Heywang, S.; Mayr, B.; Berger, H.

1989-01-01

Digital subtraction angiography (DSA) plays an important role in the management of vascular diseases of the lower extremities. A disadvantage is the lack of an automatically moving table top. We used a 1,024x1,024 matrix with a large-screen intensifier system and an automated 'stepping' facility. In 161 examinations of the arteries of the lower extremity digital peripheral arteriography was performed with and without the subtraction technique. We compared the influence of different iodine concentrations in DA and DSA. Peripheral DA proved to be equal to peripheral DSA in the region of the pelvis, thigh and knee, with no adequate contrasting being obtained merely in the region of the lower leg arteries in about 45%. It is necessary to use contrast medium at a concentration of 300 mg I/ml. The installation of an automated 'stepping' facility reduces the amount of contrast' medium needed and the exposure time. (orig.)

Self-masking subtraction tomosynthesis

International Nuclear Information System (INIS)

Chakraborty, D.P.; Yester, M.V.; Barnes, G.T.; Lakshminarayanan, A.V.

1984-01-01

The authors tested the image quality and dose savings of self-masking subtraction tomosynthesis (SST), which combines digital tomosynthesis with subtraction of a blurred self-mask. High-quality images of the inner ear of a head phantom were obtained at moderate dose savings. Although they were taken with linear motion, they did not exhibit the streaking due to off-fulcrum objects that is characteristic of conventional linear tomography. SST could reduce patient dose by a factor of at least 12 in examinations of the inner ear, and the mechanical aspects can be implemented with moderate modifications of existing instrumentation

Left-right subtraction of brain CT

International Nuclear Information System (INIS)

Ishiguchi, Tsuneo; Sakuma, Sadayuki

1986-01-01

A new image-processing method to obtain a left-right subtraction image of CT was designed for the automated detection of abnormalities in brain CT. An original CT image was divided in two by a centerline. Then the right half of the image was subtracted from the left half by calculating the absorption value of the pixels on the symmetrical positions against the centerline. The mean and the standard deviation of the absorption value of the pixels in the subtraction image were used as parameters for analysis, and the detectability of abnormal CT findings was evaluated in 100 cases - 50 cases each with normal and abnormal CT. The presence of abnormalities could be diagnosed with a sensitivity of 86 %, a specificity of 90 %, and an overall accuracy of 88 % when the borderline of these parameters between normal and abnormal CT was set at the mean + 2SD in the normal group. As a further analysis, the CT image was subdivided into several areas from a functional or anatomical viewpoint, such as cerebral vascular territories, and the left-right subtraction image of each area was obtained. The possibilities of diagnosing the location of an abnormality and of detecting smaller lesions with this method were shown. Left-right subtraction was considered to be a useful method for the detection of asymmetric abnormalities in the automated diagnosis of brain CT. (author)

Longitudinal development of subtraction performance in elementary school.

Science.gov (United States)

Artemenko, Christina; Pixner, Silvia; Moeller, Korbinian; Nuerk, Hans-Christoph

2017-10-05

A major goal of education in elementary mathematics is the mastery of arithmetic operations. However, research on subtraction is rather scarce, probably because subtraction is often implicitly assumed to be cognitively similar to addition, its mathematical inverse. To evaluate this assumption, we examined the relation between the borrow effect in subtraction and the carry effect in addition, and the developmental trajectory of the borrow effect in children using a choice reaction paradigm in a longitudinal study. In contrast to the carry effect in adults, carry and borrow effects in children were found to be categorical rather than continuous. From grades 3 to 4, children became more proficient in two-digit subtraction in general, but not in performing the borrow operation in particular. Thus, we observed no specific developmental progress in place-value computation, but a general improvement in subtraction procedures. Statement of contribution What is already known on this subject? The borrow operation increases difficulty in two-digit subtraction in adults. The carry effect in addition, as the inverse operation of borrowing, comprises categorical and continuous processing characteristics. What does this study add? In contrast to the carry effect in adults, the borrow and carry effects are categorical in elementary school children. Children generally improve in subtraction performance from grades 3 to 4 but do not progress in place-value computation in particular. © 2017 The British Psychological Society.

Development of Shimadzu digital subtraction system

International Nuclear Information System (INIS)

Nishioka, Hiroyuki; Shibata, Koichi; Shimizu, Yasumitsu; Shibata, Kenji; Wani, Hidenobu

1985-01-01

Shimadzu has recently developed a digital subtraction system. It can perform intra-arterial digital subtraction angiography (DSA) using low concentration of contrast medium, or can visualize arteries with intravenuous injection. It can extremely reduce patient's pain in angiography. Image quality of DSA has been much improved by the development of high quality image amplifiers, improvement of signal-to-noise ratio of the x-ray television unit and the development of digital disk recorders. The peak-hold subtraction method that is now under clinical study presents images of blood vessels as the trace of the flow of contrast medium. The maximum-hold memory where the maximum value of the brightness in some period is stored for every picture element is subtracted from the minimum-hold memory where the minimum value is stored, and thus images of blood vessels can be obtained. Hardware of this method is rather simple and it is expected that the amount of contrast medium may be reduced or x-ray dose of the patient may be decreased. (author)

An automated subtraction of NLO EW infrared divergences

Energy Technology Data Exchange (ETDEWEB)

Schoenherr, Marek [CERN, Theoretical Physics Department, Geneva (Switzerland)

2018-02-15

In this paper a generalisation of the Catani-Seymour dipole subtraction method to next-to-leading order electroweak calculations is presented. All singularities due to photon and gluon radiation off both massless and massive partons in the presence of both massless and massive spectators are accounted for. Particular attention is paid to the simultaneous subtraction of singularities of both QCD and electroweak origin which are present in the next-to-leading order corrections to processes with more than one perturbative order contributing at Born level. Similarly, embedding non-dipole-like photon splittings in the dipole subtraction scheme discussed. The implementation of the formulated subtraction scheme in the framework of the Sherpa Monte-Carlo event generator, including the restriction of the dipole phase space through the α-parameters and expanding its existing subtraction for NLO QCD calculations, is detailed and numerous internal consistency checks validating the obtained results are presented. (orig.)

An analysis of the influence of background subtraction and quenching on jet observables in heavy-ion collisions

CERN Document Server

Apolinario, Liliana; Cunqueiro, Leticia

2013-01-01

Subtraction of the large background in reconstruction is a key ingredient in jet studies in high-energy heavy-ion collisions at RHIC and the LHC. Here we address the question to which extent the most commonly used subtraction techniques are able to eliminate the effects of the background on the most commonly discussed observables at present: single inclusive jet distributions, dijet asymmetry and azimuthal distributions. We consider two different background subtraction methods, an area-based one implemented through the FastJet pack- age and a pedestal subtraction method, that resemble the ones used by the experimental collaborations at the LHC. We also analyze different ways of defining the optimal parame- ters in the second method. We use a toy model that easily allows variations of the background characteristics: average background level and fluctuations and azimuthal structure, but cross- checks are also done with a Monte Carlo simulator. Furthermore, we consider the influence of quenching using Q-PYTHIA o...

Soft-collinear factorization and zero-bin subtractions

International Nuclear Information System (INIS)

Chiu Juiyu; Fuhrer, Andreas; Kelley, Randall; Manohar, Aneesh V.; Hoang, Andre H.

2009-01-01

We study the Sudakov form factor for a spontaneously broken gauge theory using a (new) Δ-regulator. To be well defined, the effective theory requires zero-bin subtractions for the collinear sectors. The zero-bin subtractions depend on the gauge boson mass M and are not scaleless. They have both finite and 1/ε contributions and are needed to give the correct anomalous dimension and low-scale matching contributions. We also demonstrate the necessity of zero-bin subtractions for soft-collinear factorization. We find that after zero-bin subtractions the form factor is the sum of the collinear contributions minus a soft mass-mode contribution, in agreement with a previous result of Idilbi and Mehen in QCD. This appears to conflict with the method-of-regions approach, where one gets the sum of contributions from different regions.

Bone images from dual-energy subtraction chest radiography in the detection of rib fractures

Energy Technology Data Exchange (ETDEWEB)

Szucs-Farkas, Zsolt, E-mail: zsolt.szuecs@insel.ch [Department of Diagnostic, Interventional and Pediatric Radiology, University Hospital Bern, Freiburgstrasse 4, Bern CH-3010 (Switzerland); Lautenschlager, Katrin, E-mail: katrin@students.unibe.ch [Department of Diagnostic, Interventional and Pediatric Radiology, University Hospital Bern, Freiburgstrasse 4, Bern CH-3010 (Switzerland); Flach, Patricia M., E-mail: patricia.flach@irm.unibe.ch [Institute of Forensic Medicine, University of Bern, Freiburgstrasse 4, Bern CH-3010 (Switzerland); Ott, Daniel, E-mail: daniel.ott@insel.ch [Department of Diagnostic, Interventional and Pediatric Radiology, University Hospital Bern, Freiburgstrasse 4, Bern CH-3010 (Switzerland); Strautz, Tamara, E-mail: tamara.strautz@insel.ch [Department of Diagnostic, Interventional and Pediatric Radiology, University Hospital Bern, Freiburgstrasse 4, Bern CH-3010 (Switzerland); Vock, Peter, E-mail: peter.vock@insel.ch [Department of Diagnostic, Interventional and Pediatric Radiology, University Hospital Bern, Freiburgstrasse 4, Bern CH-3010 (Switzerland); Ruder, Thomas D., E-mail: thomas.ruder@irm.unibe.ch [Institute of Forensic Medicine, University of Bern, Freiburgstrasse 4, Bern CH-3010 (Switzerland)

2011-08-15

Objective: To assess the sensitivity and image quality of chest radiography (CXR) with or without dual-energy subtracted (ES) bone images in the detection of rib fractures. Materials and methods: In this retrospective study, 39 patients with 204 rib fractures and 24 subjects with no fractures were examined with a single exposure dual-energy subtraction digital radiography system. Three blinded readers first evaluated the non-subtracted posteroanterior and lateral chest radiographs alone, and 3 months later they evaluated the non-subtracted images together with the subtracted posteroanterior bone images. The locations of rib fractures were registered with confidence levels on a 3-grade scale. Image quality was rated on a 5-point scale. Marks by readers were compared with fracture localizations in CT as a standard of reference. Results: The sensivity for fracture detection using both methods was very similar (34.3% with standard CXR and 33.5% with ES-CXR, p = 0.92). At the patient level, both sensitivity (71.8%) and specificity (92.9%) with or without ES were identical. Diagnostic confidence was not significantly different (2.61 with CXR and 2.75 with ES-CXR, p = 0.063). Image quality with ES was rated higher than that on standard CXR (4.08 vs. 3.74, p < 0.001). Conclusions: Despite a better image quality, adding ES bone images to standard radiographs of the chest does not provide better sensitivity or improved diagnostic confidence in the detection of rib fractures.

Subtraction and dynamic MR images of breast cancer

Energy Technology Data Exchange (ETDEWEB)

Murakami, Yoshitaka; Aoki, Manabu; Harada, Junta (Jikei Univ., Tokyo (Japan). School of Medicine)

1993-04-01

The purpose of this study was to evaluate the diagnostic effectiveness of subtraction and dynamic MR imaging in patients with breast masses. In 23 breast cancers and six fibroadenomas, spin echo T1 images were obtained at 0.2 Tesla before and every minute after intravenous injection of Gd-DTPA (0.1 or 0.2 mmol/kg). Subtraction images were obtained sequentially on the CRT monitor. All breast masses were enhanced after gadolinium and stood out as bright lesions on subtraction images. The tumor margin and its extension were more precisely evaluated on subtraction MR images than on conventional postcontrast MR images. Breast cancer showed a characteristic time-intensity curve with an early peak, in contrast to fibroadenoma, which showed a gradual increase in signal intensity. Subtraction MR imaging is a simple method for the evaluation of breast masses, and further, the time-intensity curve obtained by dynamic study is helpful in the differential diagnosis of lesions. (author).

Spectral amplitude coding OCDMA using and subtraction technique.

Science.gov (United States)

Hasoon, Feras N; Aljunid, S A; Samad, M D A; Abdullah, Mohamad Khazani; Shaari, Sahbudin

2008-03-20

An optical decoding technique is proposed for a spectral-amplitude-coding-optical code division multiple access, namely, the AND subtraction technique. The theory is being elaborated and experimental results have been done by comparing a double-weight code against the existing code, Hadamard. We have proved that the and subtraction technique gives better bit error rate performance than the conventional complementary subtraction technique against the received power level.

Iodine filter imaging system for subtraction angiography using synchrotron radiation

Science.gov (United States)

Umetani, K.; Ueda, K.; Takeda, T.; Itai, Y.; Akisada, M.; Nakajima, T.

1993-11-01

A new type of real-time imaging system was developed for transvenous coronary angiography. A combination of an iodine filter and a single energy broad-bandwidth X-ray produces two-energy images for the iodine K-edge subtraction technique. X-ray images are sequentially converted to visible images by an X-ray image intensifier. By synchronizing the timing of the movement of the iodine filter into and out of the X-ray beam, two output images of the image intensifier are focused side by side on the photoconductive layer of a camera tube by an oscillating mirror. Both images are read out by electron beam scanning of a 1050-scanning-line video camera within a camera frame time of 66.7 ms. One hundred ninety two pairs of iodine-filtered and non-iodine-filtered images are stored in the frame memory at a rate of 15 pairs/s. In vivo subtracted images of coronary arteries in dogs were obtained in the form of motion pictures.

Updates to Constituent Subtraction in Heavy Ions at CMS

CERN Document Server

CMS Collaboration

2018-01-01

The latest upgrades and performance of constituent subtraction in 5.02 TeV PbPb collisions is presented. The constituent subtraction is extended through the full tracker acceptance, increasing the rapidity reach of correctly subtracted jets. A modulation in azimuthal angle is added to the subtraction, accounting for flow on an event-by-event basis and improving jet energy resolution. Closure of jet energy scale after corrections and jet energy resolution is shown for R=0.4 and R=0.8 jets, the latter for the first time in CMS Heavy-Ions.

Removal of Pb(II), Cu(II) and Cd(II) from aqueous solution by some fungi and natural adsorbents in single and multiple metal systems

International Nuclear Information System (INIS)

Shoaib, A.; Badar, T.; Aslam, N.

2011-01-01

Six fungal and 10 natural biosorbents were analyzed for their Cu(II), Cd(II) and Pb(II) uptake capacity from single, binary and ternary metal ion system. Preliminary screening biosorption of assays revealed 2 fungi (Aspergillus niger and Cunninghamella echinulata) and three natural [Cicer arietinum husk, Moringa oleifera flower and soil (clay)] adsorbents hold considerable high adsorption efficiency and capacity for 3 meta l ions amongst the adsorbents. Further biosorption trials with five elected adsorbents showed a considerable reduction in metal uptake capability of adsorbents in binary- and ternary systems as compared to singly metal system. Cd(II) manifested the highest inhibitory effect on the biosorption of other metal ions, followed by Pb(II) and Cu(II). On account of metal preference, the selectivity order for metal ion towards the studied biomass matrices was Pb(II) (40-90%) > Cd(II) (2-53%) > Cu(II) (2-30%). (author)

Parallel decompositions of Mueller matrices and polarimetric subtraction

Directory of Open Access Journals (Sweden)

Gil J.J.

2010-06-01

Full Text Available From a general formulation of the physically realizable parallel decompositions of the Mueller matrix M of a given depolarizing system, a procedure for determining the set of pure Mueller matrices susceptible to be subtracted from M is presented. This procedure provides a way to check if a given pure Mueller matrix N can be subtracted from M or not. If this check is positive, the value of the relative cross section of the subtracted component is also determined.

Removal of Ni(II), Zn(II) and Pb(II) ions from single metal aqueous solution using rice husk-based activated carbon

Energy Technology Data Exchange (ETDEWEB)

Taha, Mohd F., E-mail: faisalt@petronas.com.my; Shaharun, Maizatul S. [Fundamental and Applied Sciences Department, Universiti Teknologi PETRONAS, Bandar Seri Iskandar, 31750, Perak Darul Ridzuan (Malaysia); Shuib, Anis Suhaila, E-mail: anisuha@petronas.com.my; Borhan, Azry [Chemical Engineering Department, Universiti Teknologi PETRONAS, Bandar Seri Iskandar, 31750, Perak Darul Ridzuan (Malaysia)

2014-10-24

An attempt was made to investigate the potential of rice husk-based activated carbon as an alternative low-cost adsorbent for the removal of Ni(II), Zn(II) and Pb(II) ions from single aqueous solution. Rice husk-based activated carbon was prepared via treatment of rice husk with NaOH followed by the carbonization process at 400°C for 2 hours. Three samples, i.e. raw rice husk, rice husk treated with NaOH and rice husk-based activated carbon, were analyzed for their morphological characteristics using field-emission scanning electron microscope/energy dispersive X-ray (FESEM/EDX). These samples were also analyzed for their carbon, hydrogen, nitrogen, oxygen and silica contents using CHN elemental analyzer and FESEM/EDX. The porous properties of rice husk-based activated carbon were determined by Brunauer-Emmett-Teller (BET) surface area analyzer, and its surface area and pore volume were 255 m{sup 2}/g and 0.17 cm{sup 2}/g, respectively. The adsorption studies for the removal of Ni(II), Zn(II) and Pb(II) ions from single metal aqueous solution were carried out at a fixed initial concentration of metal ion (150 ppm) with variation amount of adsorbent (rice husk-based activated carbon) as a function of varied contact time at room temperature. The concentration of each metal ion was analyzed using atomic absorption spectrophotometer (AAS). The results obtained from adsorption studies indicate the potential of rice husk as an economically promising precursor for the preparation of activated carbon for removal of Ni(II), Zn(II) and Pb(II) ions from single aqueous solution. Isotherm and kinetic model analyses suggested that the experimental data of adsorption studies fitted well with Langmuir, Freundlich and second-order kinetic models.

Sorption of Hg(II and Pb(II Ions on Chitosan-Iron(III from Aqueous Solutions: Single and Binary Systems

Directory of Open Access Journals (Sweden)

Byron Lapo

2018-03-01

Full Text Available The present work describes the study of mercury Hg(II and lead Pb(II removal in single and binary component systems into easily prepared chitosan-iron(III bio-composite beads. Scanning electron microscopy and energy-dispersive X-ray (SEM-EDX analysis, Fourier transform infrared spectroscopy (FTIR, thermogravimetric analysis (TGA and point of zero charge (pHpzc analysis were carried out. The experimental set covered pH study, single and competitive equilibrium, kinetics, chloride and sulfate effects as well as sorption–desorption cycles. In single systems, the Langmuir nonlinear model fitted the experimental data better than the Freundlich and Sips equations. The sorbent material has more affinity to Hg(II rather than Pb(II ions, the maximum sorption capacities were 1.8 mmol·g−1 and 0.56 mmol·g−1 for Hg(II and Pb(II, respectively. The binary systems data were adjusted with competitive Langmuir isotherm model. The presence of sulfate ions in the multicomponent system [Hg(II-Pb(II] had a lesser impact on the sorption efficiency than did chloride ions, however, the presence of chloride ions improves the selectivity towards Hg(II ions. The bio-based material showed good recovery performance of metal ions along three sorption–desorption cycles.

Developing a Model to Support Students in Solving Subtraction

Directory of Open Access Journals (Sweden)

Nila Mareta Murdiyani

2013-01-01

Full Text Available Subtraction has two meanings and each meaning leads to the different strategies. The meaning of “taking away something” suggests a direct subtraction, while the meaning of “determining the difference between two numbers” is more likely to be modeled as indirect addition. Many prior researches found that the second meaning and second strategy rarely appeared in the mathematical textbooks and teacher explanations, including in Indonesia. Therefore, this study was conducted to contribute to the development of a local instruction theory for subtraction by designing instructional activities that can facilitate first grade of primary school students to develop a model in solving two digit numbers subtraction. Consequently, design research was chosen as an appropriate approach for achieving the research aim and Realistic Mathematics Education (RME was used as a guide to design the lesson. This study involved 6 students in the pilot experiment, 31 students in the teaching experiment, and a first grade teacher of SDN 179 Palembang. The  result of this study shows that the beads string could bridge students from the contextual problems (taking ginger candies and making grains bracelets to the use of the empty number line. It also shows that the empty number line could promote students to  use different strategies (direct subtraction, indirect addition, and indirect subtraction in solving subtraction problems. Based on these findings, it is recommended to apply RME in the teaching learning process to make it more meaningful for students. Keywords: Subtraction, Design Research, Realistic Mathematics Education, The Beads String, The Empty Number Line DOI: http://dx.doi.org/10.22342/jme.4.1.567.95-112

The Relationship Between Problem Size and Fixation Patterns During Addition, Subtraction, Multiplication, and Division

Directory of Open Access Journals (Sweden)

Evan T. Curtis

2016-08-01

Full Text Available Eye-tracking methods have only rarely been used to examine the online cognitive processing that occurs during mental arithmetic on simple arithmetic problems, that is, addition and multiplication problems with single-digit operands (e.g., operands 2 through 9; 2 + 3, 6 x 8 and the inverse subtraction and division problems (e.g., 5 – 3; 48 ÷ 6. Participants (N = 109 solved arithmetic problems from one of the four operations while their eye movements were recorded. We found three unique fixation patterns. During addition and multiplication, participants allocated half of their fixations to the operator and one-quarter to each operand, independent of problem size. The pattern was similar on small subtraction and division problems. However, on large subtraction problems, fixations were distributed approximately evenly across the three stimulus components. On large division problems, over half of the fixations occurred on the left operand, with the rest distributed between the operation sign and the right operand. We discuss the relations between these eye tracking patterns and other research on the differences in processing across arithmetic operations.

Dual-energy subtraction radiography of the breast

International Nuclear Information System (INIS)

Asaga, Taro; Masuzawa, Chihiro; Kawahara, Satoru; Motohashi, Hisahiko; Okamoto, Takashi; Tamura, Nobuo

1988-01-01

Dual-energy projection radiography was applied to breast examination. To perform the dual-energy subtraction radiography using a digital radiography unit, high and low-energy exposures were made at an appropriate time interval under differing X-ray exposure conditions. Dual-energy subtraction radiography was performed in 41 cancer patients in whom the tumor shadow was equivocal or the border of cancer infiltration was not clearly demonstrated by compression mammography, and 15 patients with benign diseases such as fibrocystic disease, cyst and fibroadenoma. In 21 cases out of the 41 cancer patients, the dual-energy subtraction radiography clearly visualized the malignant tumor shadows and the border of cancer infiltration and the daughter nodules by removing the shadows of normal mammary gland. On the other hand, beign diseases such as fibrocystic disease and cyst could be diagnosed as such, because the tumor shadow and the irregularly concentrated image of mammary gland disappeared by the dual-energy subtraction. These results suggest that this new technique will be useful in examination of breast masses. (author)

Dual-energy subtraction radiography of the breast

Energy Technology Data Exchange (ETDEWEB)

Asaga, Taro; Masuzawa, Chihiro; Kawahara, Satoru; Motohashi, Hisahiko; Okamoto, Takashi; Tamura, Nobuo

1988-06-01

Dual-energy projection radiography was applied to breast examination. To perform the dual-energy subtraction radiography using a digital radiography unit, high and low-energy exposures were made at an appropriate time interval under differing X-ray exposure conditions. Dual-energy subtraction radiography was performed in 41 cancer patients in whom the tumor shadow was equivocal or the border of cancer infiltration was not clearly demonstrated by compression mammography, and 15 patients with benign diseases such as fibrocystic disease, cyst and fibroadenoma. In 21 cases out of the 41 cancer patients, the dual-energy subtraction radiography clearly visualized the malignant tumor shadows and the border of cancer infiltration and the daughter nodules by removing the shadows of normal mammary gland. On the other hand, beign diseases such as fibrocystic disease and cyst could be diagnosed as such, because the tumor shadow and the irregularly concentrated image of mammary gland disappeared by the dual-energy subtraction. These results suggest that this new technique will be useful in examination of breast masses.

Digital subtraction angiography system evaluation with phantoms

International Nuclear Information System (INIS)

Wenstrup, R.S.; Sweeney, K.P.; Scholz, F.J.

1985-01-01

Advances in digital subtraction angiography imaging demonstrate the need for critical evaluation of the performance of digital subtraction equipment. The design of a phantom set for noninvasive assessment of the imaging quality of digital subtraction equipment is described; components include a remotely controlled transport system and individual patterns to evaluate the contrast and detail properties of the image intensifier, low-contrast sensitivity and resolution of the system, geometric distortion of image, linearity, mechanical and electronic stability of equipment, and effects of bone and bowel gas on iodine perception. The performance of an add-on digital radiographic system is presented, along with radiation exposure levels at the image intensifier for a range of radiographic techniques

Motion subtraction of the larynx using digital radiography

International Nuclear Information System (INIS)

Kumakawa, Kohzoh; Miyakawa, Kouichi

1990-01-01

The development of digital radiography (DR) has made it possible to analyze the contour of the laryngeal soft tissue structures in more detail than the conventional screen-film method. The authors first used the DR system for time subtraction of the larynx during inspiration and phonation. The images are acquired by means of frontal tomography of the larynx using the imaging plate during inspiration and phonation separately, and stored into the memory of the DR system. The thickness of the slices is 5.0 mm. Time subtraction between the mask image during inspiration and the live image during phonation is performed using digital processing on CRT. Superimposing the two images at the upper trachea and the thyroid cartilage of the same depth, makes it possible to measure movement of the vocal cord and false vocal cord quantitatively in three dimensions. The authors named this time subtraction as motion subtraction of the larynx. This motion subtraction image can be obtained by on-line digital processing without complicated development technique, but has so high spatial resolution. This image processing seems to be useful in functional radiographic analysis of laryngeal diseases. (author)

Digital subtraction cerebral angiography by intraarterial injection: comparison with conventional angiography

International Nuclear Information System (INIS)

Brant-Zawadzki, M.; Gould, R.; Norman, D.; Newton, T.H.; Lane, B.

1983-01-01

For 4 months, a prototype digital subtraction system was used to obtain images of the cerebral vasculature after intraarterial contrast injections. In 12 instances, the intraarterial injections were recorded with both a digital subtraction unit and conventional direct magnification film-screen system. The digital subtraction and conventional film subtraction images were compared and graded for quality and information content by three skilled observers. In addition, quantitative measurements of contrast-detail performance and spatial resolution were obtained on both the digital system and the screen-film imaging chain. In a clinical setting, both the digital subtraction and conventional film-screen systems provided similar quality images and angiographic information. Contrast-detail curves demonstrated that digital subtraction angiography outperformed conventional film technique for low-contrast objects. Digital subtraction angiography also reduced the time required to obtain the angiogram, markedly reduced film cost, and lowered the contrast agent burden

Development of digital subtraction system DAR-1200

International Nuclear Information System (INIS)

Kawai, Masumi; Shimizu, Yasumitsu; Ozaki, Takeshi; Sawada, Hiroshi; Uzuyama, Kazuhiro; Nishioka, Hiroyuki

1989-01-01

Digital subtraction angiography (DSA) has been of widespread use clinically, and it has attracted considerable attention in angiographic examination today. The merits of Shimadzu high resolution digital subtraction system DAR-1200 are reported in this paper. Furthermore, the principle and clinical usefullness of a new method of DSA called the Peak-Hold DSA are explained especially in details. (author)

Advanced Background Subtraction Applied to Aeroacoustic Wind Tunnel Testing

Science.gov (United States)

Bahr, Christopher J.; Horne, William C.

2015-01-01

An advanced form of background subtraction is presented and applied to aeroacoustic wind tunnel data. A variant of this method has seen use in other fields such as climatology and medical imaging. The technique, based on an eigenvalue decomposition of the background noise cross-spectral matrix, is robust against situations where isolated background auto-spectral levels are measured to be higher than levels of combined source and background signals. It also provides an alternate estimate of the cross-spectrum, which previously might have poor definition for low signal-to-noise ratio measurements. Simulated results indicate similar performance to conventional background subtraction when the subtracted spectra are weaker than the true contaminating background levels. Superior performance is observed when the subtracted spectra are stronger than the true contaminating background levels. Experimental results show limited success in recovering signal behavior for data where conventional background subtraction fails. They also demonstrate the new subtraction technique's ability to maintain a proper coherence relationship in the modified cross-spectral matrix. Beam-forming and de-convolution results indicate the method can successfully separate sources. Results also show a reduced need for the use of diagonal removal in phased array processing, at least for the limited data sets considered.

Sky Subtraction with Fiber-Fed Spectrograph

Science.gov (United States)

Rodrigues, Myriam

2017-09-01

"Historically, fiber-fed spectrographs had been deemed inadequate for the observation of faint targets, mainly because of the difficulty to achieve high accuracy on the sky subtraction. The impossibility to sample the sky in the immediate vicinity of the target in fiber instruments has led to a commonly held view that a multi-object fibre spectrograph cannot achieve an accurate sky subtraction under 1% contrary to their slit counterpart. The next generation of multi-objects spectrograph at the VLT (MOONS) and the planed MOS for the E-ELT (MOSAIC) are fiber-fed instruments, and are aimed to observed targets fainter than the sky continuum level. In this talk, I will present the state-of-art on sky subtraction strategies and data reduction algorithm specifically developed for fiber-fed spectrographs. I will also present the main results of an observational campaign to better characterise the sky spatial and temporal variations ( in particular the continuum and faint sky lines)."

Tomography of photon-added and photon-subtracted states

NARCIS (Netherlands)

Bazrafkan, MR; Man'ko, [No Value

The purpose of this paper is to introduce symplectic and optical tomograms of photon-added and photon-subtracted quantum states. Explicit relations for the tomograms of photon-added and photon-subtracted squeezed coherent states and squeezed number states are obtained. Generating functions for the

Digital subtraction angiography in patients with central vertigo

International Nuclear Information System (INIS)

Inamori, Toru; Takayasu, Yukio; Umetani, Yoshio; Taruoka, Akinori.

1985-01-01

Digital subtraction angiography (DSA) is a recently developed non-invasive intravenous angiography which has become possible through real time digital subtraction of x-ray transmission data from an image intensifier and television system. The output signals of the image intensifier-television camera system are digitized by an analog-digital converter. The digital information, 512x512 pixels and 9 bits deep, is fed into the image processing assembly after logarithmic amplification, where 2-8 frames are added and subtracted from mask images for the final digital images. Intravenous digital subtraction angiography was performed in 21 patients with intractable dizzy spells of central origin resistant to treatment. These patients showed some signs of CNS disturbance, although there were no significant findings on CT scans. Surprisingly, findings were abnormal in 14 of 21 patients (66.7%). DSA is, therefore, considered to be an important aid in the diagnosis of vertigo of the central type. (J.P.N.)

A study on the geometric correction for the digital subtraction radiograph

International Nuclear Information System (INIS)

Lim, Suk Young; Koh, Kwang Joon

2001-01-01

To develop a new subtraction program for registering digital images based on the correspondence of anatomic structures. The digital periapical images were obtained by Digora system with Rinn XCP equipment after translation of 1-16 mm, and rotation of 2-20 at the premolar and molar areas of the human dried mandible. The new subtraction program, NIH Image program and Emago/Advanced program were compared by the peak-signal -to noise ratio (PSNR). The new subtraction program was superior to NIH Images program and Emago/Advanced program up to 16 mm translation and horizontal angulation up to 4. The new subtraction program can be used for subtracting digital periapical images

NNLO jet cross sections by subtraction

Energy Technology Data Exchange (ETDEWEB)

Somogyi, G.; Bolzoni, P. [DESY, Platanenallee 6, D-15738 Zeuthen (Germany); Trocsanyi, Z. [CERN PH-TH, on leave from University of Debrecen and Institute of Nuclear Research of HAS, H-4001 P.O.Box 51 (Hungary)

2010-08-15

We report on the computation of a class of integrals that appear when integrating the so-called iterated singly-unresolved approximate cross section of the NNLO subtraction scheme of Refs. [G. Somogyi, Z. Trocsanyi, and V. Del Duca, JHEP 06, 024 (2005), (arXiv:hep-ph/0502226); G. Somogyi and Z. Trocsanyi, (2006), (arXiv:hep-ph/0609041); G. Somogyi, Z. Trocsanyi, and V. Del Duca, JHEP 01, 070 (2007), (arXiv:hep-ph/0609042); G. Somogyi and Z. Trocsanyi, JHEP 01, 052 (2007), (arXiv:hep-ph/0609043)] over the factorised phase space of unresolved partons. The integrated approximate cross section itself can be written as the product of an insertion operator (in colour space) times the Born cross section. We give selected results for the insertion operator for processes with two and three hard partons in the final state.

NNLO jet cross sections by subtraction

International Nuclear Information System (INIS)

Somogyi, G.; Bolzoni, P.; Trocsanyi, Z.

2010-01-01

We report on the computation of a class of integrals that appear when integrating the so-called iterated singly-unresolved approximate cross section of the NNLO subtraction scheme of Refs. [G. Somogyi, Z. Trocsanyi, and V. Del Duca, JHEP 06, 024 (2005), (arXiv:hep-ph/0502226); G. Somogyi and Z. Trocsanyi, (2006), (arXiv:hep-ph/0609041); G. Somogyi, Z. Trocsanyi, and V. Del Duca, JHEP 01, 070 (2007), (arXiv:hep-ph/0609042); G. Somogyi and Z. Trocsanyi, JHEP 01, 052 (2007), (arXiv:hep-ph/0609043)] over the factorised phase space of unresolved partons. The integrated approximate cross section itself can be written as the product of an insertion operator (in colour space) times the Born cross section. We give selected results for the insertion operator for processes with two and three hard partons in the final state.

Model Checking Timed Automata with Priorities using DBM Subtraction

DEFF Research Database (Denmark)

David, Alexandre; Larsen, Kim Guldstrand; Pettersson, Paul

2006-01-01

In this paper we describe an extension of timed automata with priorities, and efficient algorithms to compute subtraction on DBMs (difference bounded matrices), needed in symbolic model-checking of timed automata with priorities. The subtraction is one of the few operations on DBMs that result...... in a non-convex set needing sets of DBMs for representation. Our subtraction algorithms are efficient in the sense that the number of generated DBMs is significantly reduced compared to a naive algorithm. The overhead in time is compensated by the gain from reducing the number of resulting DBMs since...... this number affects the performance of symbolic model-checking. The uses of the DBM subtraction operation extend beyond timed automata with priorities. It is also useful for allowing guards on transitions with urgent actions, deadlock checking, and timed games....

Evaluation of sacroiliitis: contrast-enhanced MRI with subtraction technique

Energy Technology Data Exchange (ETDEWEB)

Algin, Oktay; Gokalp, Gokhan; Baran, Bulent; Ocakoglu, Gokhan; Yazici, Zeynep [Uludag University, Medical Faculty, Department of Radiology, Gorukle, Bursa (Turkey)

2009-10-15

The purpose of the study was to investigate the diagnostic value of contrast-enhanced MRI using the subtraction technique in the detection of active sacroiliitis. Magnetic resonance imaging was performed in 8 asymptomatic volunteers and 50 patients with clinically suspected active sacroiliitis. On precontrast MR images, T1-weighted spin-echo images with and without fat saturation (T1WFS and T1W), STIR and 3D-FLASH images with fat saturation were obtained in the semicoronal plane using a 1.5 Tesla imager. Postcontrast MRI was performed using the same T1WFS sequence as before contrast injection for all volunteers and patients. Postcontrast images were subtracted from fat-suppressed precontrast images. Enhancement within the joint space and bone marrow was considered to demonstrate active sacroiliitis. In 50 patients (100 sacroiliac joints [SIJs]), 40 (76 SIJs) were considered to have active sacroiliitis based on MR images. Bone marrow edema was present in 33 patients (62 SIJs) on STIR images. Routine MRI allowed identification of contrast enhancement in SIJs on postcontrast T1WFS images in 31 patients (49 SIJs). Contrast enhancement was observed in 40 patients (76 SIJs) who were examined by MRI using the subtraction technique. Contrast enhancement was significantly more conspicuous on subtraction images than on non-subtracted postcontrast T1WFS images (Mann-Whitney U test, p<0.001). Contrast-enhanced MRI with subtraction technique may be useful for early detection of active sacroiliitis. (orig.)

Digital subtraction radiographic evaluation of the standardize periapical intraoral radiographs

International Nuclear Information System (INIS)

Cho, Bong Hae; Nah, Kyung Soo

1993-01-01

The geometrically standardized intraoral radiographs using 5 occlusal registration material were taken serially from immediate, 1 day, 2, 4, 8, 12 and 16 weeks after making the bite blocks. The qualities of those subtracted images were evaluated to check the degree of reproducibility of each impression material. The results were as follows: 1. The standard deviations of the grey scales of the overall subtracted images were 4.9 for Exaflex, 7.2 for Pattern resin, 9.0 for Tooth Shade Acrylic, 12.2 for XCP only, 14.8 for Impregum. 2. The standard deviation of the grey scales of the overall subtracted images were grossly related to those of the localized horizontal line of interest. 3. Exaflex which showed the best subtracted image quality had 15 cases of straight, 14 cases of wave, 1 case of canyon shape. Impregum which showed the worst subtracted image quality had 4 cases of straight, 8 cases of wave, 18 cases of canyon shape respectively.

Temporal subtraction in chest radiography: Automated assessment of registration accuracy

International Nuclear Information System (INIS)

Armato, Samuel G. III; Doshi, Devang J.; Engelmann, Roger; Croteau, Charles L.; MacMahon, Heber

2006-01-01

Radiologists routinely compare multiple chest radiographs acquired from the same patient over time to more completely understand changes in anatomy and pathology. While such comparisons are achieved conventionally through a side-by-side display of images, image registration techniques have been developed to combine information from two separate radiographic images through construction of a 'temporal subtraction image'. Although temporal subtraction images provide a powerful mechanism for the enhanced visualization of subtle change, errors in the clinical evaluation of these images may arise from misregistration artifacts that can mimic or obscure pathologic change. We have developed a computerized method for the automated assessment of registration accuracy as demonstrated in temporal subtraction images created from radiographic chest image pairs. The registration accuracy of 150 temporal subtraction images constructed from the computed radiography images of 72 patients was rated manually using a five-point scale ranging from '5-excellent' to '1-poor'; ratings of 3, 4, or 5 reflected clinically acceptable subtraction images, and ratings of 1 or 2 reflected clinically unacceptable images. Gray-level histogram-based features and texture measures are computed at multiple spatial scales within a 'lung mask' region that encompasses both lungs in the temporal subtraction images. A subset of these features is merged through a linear discriminant classifier. With a leave-one-out-by-patient training/testing paradigm, the automated method attained an A z value of 0.92 in distinguishing between temporal subtraction images that demonstrated clinically acceptable and clinically unacceptable registration accuracy. A second linear discriminant classifier yielded an A z value of 0.82 based on a feature subset selected from an independent database of digitized film images. These methods are expected to advance the clinical utility of temporal subtraction images for chest

Subtractive fabrication of ferroelectric thin films with precisely controlled thickness

Science.gov (United States)

Ievlev, Anton V.; Chyasnavichyus, Marius; Leonard, Donovan N.; Agar, Joshua C.; Velarde, Gabriel A.; Martin, Lane W.; Kalinin, Sergei V.; Maksymovych, Petro; Ovchinnikova, Olga S.

2018-04-01

The ability to control thin-film growth has led to advances in our understanding of fundamental physics as well as to the emergence of novel technologies. However, common thin-film growth techniques introduce a number of limitations related to the concentration of defects on film interfaces and surfaces that limit the scope of systems that can be produced and studied experimentally. Here, we developed an ion-beam based subtractive fabrication process that enables creation and modification of thin films with pre-defined thicknesses. To accomplish this we transformed a multimodal imaging platform that combines time-of-flight secondary ion mass spectrometry with atomic force microscopy to a unique fabrication tool that allows for precise sputtering of the nanometer-thin layers of material. To demonstrate fabrication of thin-films with in situ feedback and control on film thickness and functionality we systematically studied thickness dependence of ferroelectric switching of lead-zirconate-titanate, within a single epitaxial film. Our results demonstrate that through a subtractive film fabrication process we can control the piezoelectric response as a function of film thickness as well as improve on the overall piezoelectric response versus an untreated film.

On the usefulness of portal monitor unit subtraction in radiation therapy

International Nuclear Information System (INIS)

Kuperman, Vadim Y; Lubich, Leslie M

2003-01-01

In order to avoid additional dose to patients caused by portal imaging with megavoltage x-rays, portal monitor units (MUs) are frequently subtracted from the actual treatment MUs. This study examines the usefulness of portal MU subtraction in radiation therapy. For 11 prostate cancer patients treated with 23 MV photons, dose to prostate due to portal filming with 6 MV photons was determined. In all 11 patients subtraction of portal MU values from the actual treatment MUs resulted in a small underdosing of the prostate with an average treatment error of -0.5%. Portal filming without MU subtraction would cause small overdosing of the prostate with an average treatment error of 1.2%. The results of this study indicate that the benefits of portal MU subtraction are in doubt if (a) the energy of treatment x-rays is much higher than that of the portal x-rays and/or (b) when radiotherapy is performed with physical wedges. Based on the obtained results, we argue against unconditional use of the portal MU subtraction method to eliminate the dose from portal imaging

A new registration method with voxel-matching technique for temporal subtraction images

Science.gov (United States)

Itai, Yoshinori; Kim, Hyoungseop; Ishikawa, Seiji; Katsuragawa, Shigehiko; Doi, Kunio

2008-03-01

A temporal subtraction image, which is obtained by subtraction of a previous image from a current one, can be used for enhancing interval changes on medical images by removing most of normal structures. One of the important problems in temporal subtraction is that subtraction images commonly include artifacts created by slight differences in the size, shape, and/or location of anatomical structures. In this paper, we developed a new registration method with voxel-matching technique for substantially removing the subtraction artifacts on the temporal subtraction image obtained from multiple-detector computed tomography (MDCT). With this technique, the voxel value in a warped (or non-warped) previous image is replaced by a voxel value within a kernel, such as a small cube centered at a given location, which would be closest (identical or nearly equal) to the voxel value in the corresponding location in the current image. Our new method was examined on 16 clinical cases with MDCT images. Preliminary results indicated that interval changes on the subtraction images were enhanced considerably, with a substantial reduction of misregistration artifacts. The temporal subtraction images obtained by use of the voxel-matching technique would be very useful for radiologists in the detection of interval changes on MDCT images.

SU-D-17A-02: Four-Dimensional CBCT Using Conventional CBCT Dataset and Iterative Subtraction Algorithm of a Lung Patient

International Nuclear Information System (INIS)

Hu, E; Lasio, G; Yi, B

2014-01-01

Purpose: The Iterative Subtraction Algorithm (ISA) method generates retrospectively a pre-selected motion phase cone-beam CT image from the full motion cone-beam CT acquired at standard rotation speed. This work evaluates ISA method with real lung patient data. Methods: The goal of the ISA algorithm is to extract motion and no- motion components form the full reconstruction CBCT. The workflow consists of subtracting from the full CBCT all of the undesired motion phases and obtain a motion de-blurred single-phase CBCT image, followed by iteration of this subtraction process. ISA is realized as follows: 1) The projections are sorted to various phases, and from all phases, a full reconstruction is performed to generate an image CTM. 2) Generate forward projections of CTM at the desired phase projection angles, the subtraction of projection and the forward projection will reconstruct a CTSub1, which diminishes the desired phase component. 3) By adding back the CTSub1 to CTm, no motion CBCT, CTS1, can be computed. 4) CTS1 still contains residual motion component. 5) This residual motion component can be further reduced by iteration.The ISA 4DCBCT technique was implemented using Varian Trilogy accelerator OBI system. To evaluate the method, a lung patient CBCT dataset was used. The reconstruction algorithm is FDK. Results: The single phase CBCT reconstruction generated via ISA successfully isolates the desired motion phase from the full motion CBCT, effectively reducing motion blur. It also shows improved image quality, with reduced streak artifacts with respect to the reconstructions from unprocessed phase-sorted projections only. Conclusion: A CBCT motion de-blurring algorithm, ISA, has been developed and evaluated with lung patient data. The algorithm allows improved visualization of a single phase motion extracted from a standard CBCT dataset. This study has been supported by National Institute of Health through R01CA133539

Combined nuclear and digital subtraction contrast arthrography in painful knee prosthesis

International Nuclear Information System (INIS)

Namasivayam, J.; Forrester, A.; Poon, F.W.; Cuthbert, G.F.; McKillop, J.H.; Bryan, A.S.

1992-01-01

The evaluation of a painful knee prosthesis remains a difficult problem for both orthopaedic surgeons and radiologists. We have compared digital subtraction arthrography with nuclear-arthrography in 7 patients with a painful knee prosthesis. Three patients showed a loose tibial component, demonstrated by both digital subtraction and nuclear arthrography. All 3 underwent revision of their prosthesis. One patient had an equivocal digital subtraction arthrogram and negative nuclear arthrogram, while both studies were negative in the 3 remaining patients. Nuclear arthrography is a simple procedure and can provide useful additional information when combined with digital subtraction arthrography. (orig.)

Arthrography of painful hips following arthroplasty: Digital versus plain film subtraction

Energy Technology Data Exchange (ETDEWEB)

Walker, C W; FitzRandolph, R L; Dalrymple, G V [Arkansas Univ. for Medical Sciences, Little Rock, AR (USA). Dept. of Radiology John McClellan Memorial Veterans Hospital, Little Rock, AR (USA); Collins, D N [Arkansas Univ. for Medical Sciences, Little Rock, AR (USA). Dept. of Orthopedics John McClellan Memorial Veterans Hospital, Little Rock, AR (USA)

1991-08-01

Digital and manual subtraction images obtained during the arthrographic evaluation of 78 painful hip prostheses were reviewed retrospectively. Revision arthroplasty was performed in 53 of these cases, and the arthrographic and surgical findings were correlated. The digital and manual subtraction images were evaluated without knowledge of the surgical results using established criteria for component loosening. The difference between detection of femoral component loosening on digital as opposed to manual subtraction images was statistically significant (P < 0.05). This study demonstrates that digital subtraction improves the evaluation of femoral component loosening in painful hip prostheses. (orig./GDG).

[sup 99m]Tc-RBC subtraction scintigraphy; Assessmet of bleeding site and rate

Energy Technology Data Exchange (ETDEWEB)

Inagaki, Syoichi; Tonami, Syuichi; Yasui, Masakazu; Kuranishi, Makoto; Sugishita, Kouki; Nakamura, Mamoru (Toyama Medical and Pharmaceutical Univ. (Japan). Hospital)

1994-03-01

Sequential abdominal scintigrams with [sup 99m]Tc-labelled red blood cells (RBC) were subtracted for observing a site of gastrointestinal bleeding and calculating the bleeding rate. This method is technically very easy and can detect the site of bleeding with the minimum rate, as low as 0.2 ml/min., in a phantom experiment. In 23 cases with final diagnosis of gastrointestinal bleeding, conventional non-subtraction scintigraphy detected only 30% (7/23), but subtraction scintigraphy detected 61% (14/23). It was concluded that subtraction scintigraphy had higher sensitivity than conventional scintigraphy for early diagnosing bleeding. A combination of non-subtraction and subtraction scintigraphy is recommended to detect a site of gastrointestinal bleeding in a clinical setting. (author).

Bone marrow edema pattern identification in patients with lytic bone lesions using digital subtraction angiography-like bone subtraction on large-area detector computed tomography.

Science.gov (United States)

Gondim Teixeira, Pedro Augusto; Hossu, Gabriela; Lecocq, Sophie; Razeto, Marco; Louis, Matthias; Blum, Alain

2014-03-01

The objective of this study was to evaluate the performance of digital subtraction angiography (DSA)-like bone subtraction with 2 different registration methods for the identification of bone marrow edema pattern (BMEP) in patients with lytic bone lesions, using magnetic resonance imaging as the criterion standard. Fifty-five patients with a lytic bone lesion were included in this prospective study with approval from the ethics committee. All patients underwent magnetic resonance imaging and low-dose computed tomographic (CT) perfusion after signing an informed consent. Two CT volumes were used for bone subtraction, which was performed with 2 different algorithms (rigid and nonrigid). Enhancement at the nonlytic bone marrow was considered as a sign of BMEP. Two readers evaluated the images blindly. The presence of BMEP on bone-subtracted CT images was evaluated subjectively and quantitatively. Image quality was assessed. Magnetic resonance imaging was used as the criterion standard. Using a rigid registration method, the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of CT with DSA-like bone subtraction BMEP was 77%, 100%, 100%, 68%, and 85%, respectively. The interobserver agreement was good (κ, 0.782). Image quality was better using a nonrigid registration. With this algorithm, artifacts interfered with image interpretation in only 5% of cases. However, there was a noticeable drop in sensitivity and negative predictive value when a nonrigid algorithm was used: 56% and 52%, respectively. The interobserver agreement was average with a nonrigid subtraction algorithm. Computed tomography with DSA-like bone subtraction is sensitive and highly specific for the identification of BMEP associated with lytic bone lesions. Rigid registering should be preferred, but nonrigid algorithms can be used as a second option when artifacts interfere with image interpretation.

The study of myocardial ischemic quality with weighted-subtraction-bull's-eye analysis

International Nuclear Information System (INIS)

Chen Wuduan; Tian Jiahe; Hou Qingtian

1993-01-01

Weighted-Subtraction-Bull's-eye analysis was studied in 33 normal subjects and 58 patients with coronary artery disease after dipyridamole 99m Tc-MIBI myocardial SPECT imaging. Two kinds of Bull's-eye were produced: (1) subtract rest from 1.2 times dipyridamole from 1.2 times rest Bull's-eye; (2) subtract dipyridamole Bull's-eye. The results showed that the weighted-subtraction-Bull's-eye could clearly displayed the location and puality of ischemic myocardium. And also 74% segments showed so called combined ischemic i.e the blood perfusion reduced, increased and sustained simultaneously after dipyridamole. Therefore weighted-subtraction-Bull's-eye analysis had provided a new method for determination of the quality of ischemia

Digital subtraction cardiopulmonary angiography using FCR (Fuji computed radiography)

International Nuclear Information System (INIS)

Tanimura, Shigeo; Tomoyasu, Hiroshi; Banba, Jiro; Masaki, Mikio; Kanno, Yukio; Abe, Kazuo

1987-01-01

Digital subtraction cardiopulmonary angiography using FCR was performed on 46 patients including lung cancer, mediastinal tumor, giant bullous formation and others. The images of digital subtraction for pulmonary artery, pulmonary vein and thoracic aorta were studied by comparing to the conventional pulmonary angiogram. Good images of pulmonary artery due to digital subtraction were obtained in 80 % of the 45 cases. This method needed only half volume of contrast media compared to the conventional for obtaining good images and thus reduced side effect. Therefore this method seems to be an usefull pre-operative examination in various chest diseases, especially in case of lung cancer. (author)

N-jettiness Subtractions for NNLO QCD calculations

International Nuclear Information System (INIS)

Gaunt, Jonathan R.; Stahlhofen, Maximilian; Tackmann, Frank J.; Walsh, Jonathan R.; California Univ., CA

2015-05-01

We present a subtraction method utilizing the N-jettiness observable, Τ N , to perform QCD calculations for arbitrary processes at next-to-next-to-leading order (NNLO). Our method employs soft-collinear effective theory (SCET) to determine the IR singular contributions of N-jet cross sections for Τ N → 0, and uses these to construct suitable Τ N -subtractions. The construction is systematic and economic, due to being based on a physical observable. The resulting NNLO calculation is fully differential and in a form directly suitable for combining with resummation and parton showers. We explain in detail the application to processes with an arbitrary number of massless partons at lepton and hadron colliders together with the required external inputs in the form of QCD amplitudes and lower-order calculations. We provide explicit expressions for the Τ N -subtractions at NLO and NNLO. The required ingredients are fully known at NLO, and at NNLO for processes with two external QCD partons. The remaining NNLO ingredient for three or more external partons can be obtained numerically with existing NNLO techniques. As an example, we employ our method to obtain the NNLO rapidity spectrum for Drell-Yan and gluon-fusion Higgs production. We discuss aspects of numerical accuracy and convergence and the practical implementation. We also discuss and comment on possible extensions, such as more-differential subtractions, necessary steps for going to N 3 LO, and the treatment of massive quarks.

Value of blood-pool subtraction in cardiac indium-111-labeled platelet imaging

Energy Technology Data Exchange (ETDEWEB)

Machac, J.; Vallabhajosula, S.; Goldman, M.E.; Goldsmith, S.J.; Palestro, C.; Strashun, A.; Vaquer, R.; Phillips, R.A.; Fuster, V. (Mt. Sinai Medical Center, New York, NY (USA))

1989-09-01

Blood-pool subtraction has been proposed to enhance {sup 111}In-labeled platelet imaging of intracardiac thrombi. We tested the accuracy of labeled platelet imaging, with and without blood-pool subtraction, in ten subjects with cardiac thrombi of varying age, eight with endocarditis being treated with antimicrobial therapy and ten normal controls. Imaging was performed early after labeled platelet injection (24 hr or less) and late (48 hr or more). Blood-pool subtraction was carried out. All images were graded subjectively by four experienced, blinded readers. Detection accuracy was measured by the sensitivity at three fixed levels of specificity estimated from receiver operator characteristic curve analysis and tested by three-way analysis of variance. Detection accuracy was generally improved on delayed images. Blood-pool subtraction did not improve accuracy. Although blood-pool subtraction increased detection sensitivity, this was offset by decreased specificity. For this population studied, blood-pool subtraction did not improve subjective detection of abnormal platelet deposition by 111In platelet imaging.

Value of blood-pool subtraction in cardiac indium-111-labeled platelet imaging

International Nuclear Information System (INIS)

Machac, J.; Vallabhajosula, S.; Goldman, M.E.; Goldsmith, S.J.; Palestro, C.; Strashun, A.; Vaquer, R.; Phillips, R.A.; Fuster, V.

1989-01-01

Blood-pool subtraction has been proposed to enhance 111 In-labeled platelet imaging of intracardiac thrombi. We tested the accuracy of labeled platelet imaging, with and without blood-pool subtraction, in ten subjects with cardiac thrombi of varying age, eight with endocarditis being treated with antimicrobial therapy and ten normal controls. Imaging was performed early after labeled platelet injection (24 hr or less) and late (48 hr or more). Blood-pool subtraction was carried out. All images were graded subjectively by four experienced, blinded readers. Detection accuracy was measured by the sensitivity at three fixed levels of specificity estimated from receiver operator characteristic curve analysis and tested by three-way analysis of variance. Detection accuracy was generally improved on delayed images. Blood-pool subtraction did not improve accuracy. Although blood-pool subtraction increased detection sensitivity, this was offset by decreased specificity. For this population studied, blood-pool subtraction did not improve subjective detection of abnormal platelet deposition by 111In platelet imaging

NNLO jet cross sections by subtraction

Science.gov (United States)

Somogyi, G.; Bolzoni, P.; Trócsányi, Z.

2010-08-01

We report on the computation of a class of integrals that appear when integrating the so-called iterated singly-unresolved approximate cross section of the NNLO subtraction scheme of Refs. [G. Somogyi, Z. Trócsányi, and V. Del Duca, JHEP 06, 024 (2005), arXiv:hep-ph/0502226; G. Somogyi and Z. Trócsányi, (2006), arXiv:hep-ph/0609041; G. Somogyi, Z. Trócsányi, and V. Del Duca, JHEP 01, 070 (2007), arXiv:hep-ph/0609042; G. Somogyi and Z. Trócsányi, JHEP 01, 052 (2007), arXiv:hep-ph/0609043] over the factorised phase space of unresolved partons. The integrated approximate cross section itself can be written as the product of an insertion operator (in colour space) times the Born cross section. We give selected results for the insertion operator for processes with two and three hard partons in the final state.

Ictal cerebral perfusion patterns in partial epilepsy: SPECT subtraction

International Nuclear Information System (INIS)

Lee, Hyang Woon; Hong, Seung Bong; Tae, Woo Suk; Kim, Sang Eun; Seo, Dae Won; Jeong, Seung Cheol; Yi, Ji Young; Hong, Seung Chyul

2000-01-01

To investigate the various ictal perfusion patterns and find the relationships between clinical factors and different perfusion patterns. Interictal and ictal SPECT and SPECT subtraction were performed in 61 patients with partial epilepsy. Both positive images showing ictal hyperperfusion and negative images revealing ictal hypoperfusion were obtained by SPECT subtraction. The ictal perfusion patterns of subtracted SPECT were classified into focal hyperperfusion, hyperperfusion-plus, combined hyperperfusion-hypoperfusion, and focal hypoperfusion only. The concordance rates with epileptic focus were 91.8% in combined analysis of ictal hyperperfusion and hypoperfusion images of subtracted SPECT, 85.2% in hyperperfusion images only of subtracted SPECT, and 68.9% in conventional ictal SPECT analysis. Ictal hypoperfusion occurred less frequently in temporal lobe epilepsy (TLE) than extratemporal lobe epilepsy. Mesial temporal hyperperfusion alone was seen only in mesial TLE while lateral temporal hyperperfusion alone was observed only in neocortical TLE. Hippocampal sclerosis had much lower incidence of ictal hypoperfusion than any other pathology. Some patients showed ictal hypoperfusion at epileptic focus with ictal hyperperfusion in the neighboring brain regions where ictal discharges propagated. Hypoperfusion as well as hyperperfusion in ictal SPECT should be considered for localizing epileptic focus. Although the mechanism of ictal hypoperfusion could be an intra-ictal early exhaustion of seizure focus or a steal phenomenon by the propagation of ictal discharges to adjacent brain areas, further study is needed to elucidate it.=20

Ictal cerebral perfusion patterns in partial epilepsy: SPECT subtraction

Energy Technology Data Exchange (ETDEWEB)

Lee, Hyang Woon; Hong, Seung Bong; Tae, Woo Suk; Kim, Sang Eun; Seo, Dae Won; Jeong, Seung Cheol; Yi, Ji Young; Hong, Seung Chyul [Sungkyunkwan Univ. School of Medicine, Seoul (Korea, Republic of)

2000-06-01

To investigate the various ictal perfusion patterns and find the relationships between clinical factors and different perfusion patterns. Interictal and ictal SPECT and SPECT subtraction were performed in 61 patients with partial epilepsy. Both positive images showing ictal hyperperfusion and negative images revealing ictal hypoperfusion were obtained by SPECT subtraction. The ictal perfusion patterns of subtracted SPECT were classified into focal hyperperfusion, hyperperfusion-plus, combined hyperperfusion-hypoperfusion, and focal hypoperfusion only. The concordance rates with epileptic focus were 91.8% in combined analysis of ictal hyperperfusion and hypoperfusion images of subtracted SPECT, 85.2% in hyperperfusion images only of subtracted SPECT, and 68.9% in conventional ictal SPECT analysis. Ictal hypoperfusion occurred less frequently in temporal lobe epilepsy (TLE) than extratemporal lobe epilepsy. Mesial temporal hyperperfusion alone was seen only in mesial TLE while lateral temporal hyperperfusion alone was observed only in neocortical TLE. Hippocampal sclerosis had much lower incidence of ictal hypoperfusion than any other pathology. Some patients showed ictal hypoperfusion at epileptic focus with ictal hyperperfusion in the neighboring brain regions where ictal discharges propagated. Hypoperfusion as well as hyperperfusion in ictal SPECT should be considered for localizing epileptic focus. Although the mechanism of ictal hypoperfusion could be an intra-ictal early exhaustion of seizure focus or a steal phenomenon by the propagation of ictal discharges to adjacent brain areas, further study is needed to elucidate it.

Hardware Implementation of a Bilateral Subtraction Filter

Science.gov (United States)

Huertas, Andres; Watson, Robert; Villalpando, Carlos; Goldberg, Steven

2009-01-01

A bilateral subtraction filter has been implemented as a hardware module in the form of a field-programmable gate array (FPGA). In general, a bilateral subtraction filter is a key subsystem of a high-quality stereoscopic machine vision system that utilizes images that are large and/or dense. Bilateral subtraction filters have been implemented in software on general-purpose computers, but the processing speeds attainable in this way even on computers containing the fastest processors are insufficient for real-time applications. The present FPGA bilateral subtraction filter is intended to accelerate processing to real-time speed and to be a prototype of a link in a stereoscopic-machine- vision processing chain, now under development, that would process large and/or dense images in real time and would be implemented in an FPGA. In terms that are necessarily oversimplified for the sake of brevity, a bilateral subtraction filter is a smoothing, edge-preserving filter for suppressing low-frequency noise. The filter operation amounts to replacing the value for each pixel with a weighted average of the values of that pixel and the neighboring pixels in a predefined neighborhood or window (e.g., a 9 9 window). The filter weights depend partly on pixel values and partly on the window size. The present FPGA implementation of a bilateral subtraction filter utilizes a 9 9 window. This implementation was designed to take advantage of the ability to do many of the component computations in parallel pipelines to enable processing of image data at the rate at which they are generated. The filter can be considered to be divided into the following parts (see figure): a) An image pixel pipeline with a 9 9- pixel window generator, b) An array of processing elements; c) An adder tree; d) A smoothing-and-delaying unit; and e) A subtraction unit. After each 9 9 window is created, the affected pixel data are fed to the processing elements. Each processing element is fed the pixel value for

Digital subtraction radiography evaluation of the bone repair process of chronic apical periodontitis after root canal treatment.

Science.gov (United States)

Benfica e Silva, J; Leles, C R; Alencar, A H G; Nunes, C A B C M; Mendonça, E F

2010-08-01

To monitor radiographically the progress of bone repair within chronic periapical lesions after root canal treatment using digital subtraction radiography (DSR). Twelve patients with 17 single-rooted teeth with chronic apical periodontitis associated with an infected necrotic pulp were selected for root canal treatment. Periapical radiographs were taken before treatment (baseline) and immediately post-treatment, 45, 90, 135 and 180 days after treatment. The radiographic protocol included the use of individualized film holders with silicone bite blocks. The six radiographic images were digitized and submitted to digital subtraction using DSR software, resulting in five subtracted images (SI). Quantitative analysis of these SI was performed using Image Tool software to assess pixel value changes, considering a step-wedge as the gold standard and a cut-off value of 128 pixels. The aim was to identify any increase or decrease in mineral density in the region of the periapical lesion. A minor decrease in mineral density at the canal filling session and a significant progressive mineral gain in the following evaluations (P < 0.001) occurred. Pairwise comparison of pixel grey values revealed that only the 180-day follow-up differed significantly from the previous SI. Digital subtraction radiography is a useful method for evaluating the progress of bone repair after root canal treatment. Noticeable mineral gain was observed approximately 90 days after root canal filling and definite bone repair after 180 days.

AutoDipole - Automated generation of dipole subtraction terms

International Nuclear Information System (INIS)

Hasegawa, K.; Uwer, P.

2009-11-01

We present an automated generation of the subtraction terms for next-to-leading order QCD calculations in the Catani-Seymour dipole formalism. For a given scattering process with n external particles our Mathematica package generates all dipole terms, allowing for bothmassless and massive dipoles. The numerical evaluation of the subtraction terms proceeds with MadGraph, which provides Fortran code for the necessary scattering amplitudes. Checks of the numerical stability are discussed. (orig.)

AutoDipole - Automated generation of dipole subtraction terms

Energy Technology Data Exchange (ETDEWEB)

Hasegawa, K.; Uwer, P. [Humboldt-Universitaet, Berlin (Germany). Inst. fuer Physik; Moch, S. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany)

2009-11-15

We present an automated generation of the subtraction terms for next-to-leading order QCD calculations in the Catani-Seymour dipole formalism. For a given scattering process with n external particles our Mathematica package generates all dipole terms, allowing for bothmassless and massive dipoles. The numerical evaluation of the subtraction terms proceeds with MadGraph, which provides Fortran code for the necessary scattering amplitudes. Checks of the numerical stability are discussed. (orig.)

ECG-gating in non-cardiac digital subtraction angiography

International Nuclear Information System (INIS)

Gattoni, F.; Baldini, V.; Cairo, F.

1987-01-01

This paper reports the results of the ECG-gating in non-cardiac digital subtraction angiography (DSA). One hundred and fifteen patients underwent DSA (126 examinations); ECG-gating was applied in 66/126 examinations: images recorded at 70% of R wave were subtracted. Artifacts produced by vascular movements were evaluated in all patients: only 40 examinations, carried out whithout ECG-gating, showed vascular artifacts. The major advantage of the ECG-gated DSA is the more efficent subtraction because of the better images superimposition: therefore, ECG-gating can be clinically helpful. On the contrary, it could be a problem in arrhytmic or bradycardic patients. ECG-gating is helpful in DSA imaging of the thoracic and abdominal aorta and of the cervical and renal arteries. In the examinations of peripheral vessels of the limbs it is not so efficent as in the trunk or in the neck

Automating dipole subtraction

Energy Technology Data Exchange (ETDEWEB)

Hasegawa, K.; Moch, S. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Uwer, P. [Karlsruhe Univ. (T.H.) (Germany). Inst. fuer Theoretische Teilchenphysik

2008-07-15

We report on automating the Catani-Seymour dipole subtraction which is a general procedure to treat infrared divergences in real emission processes at next-to-leading order in QCD. The automatization rests on three essential steps: the creation of the dipole terms, the calculation of the color linked squared Born matrix elements, and the evaluation of different helicity amplitudes. The routines have been tested for a number of complex processes, such as the real emission process gg{yields}t anti tggg. (orig.)

Automating dipole subtraction

International Nuclear Information System (INIS)

Hasegawa, K.; Moch, S.; Uwer, P.

2008-07-01

We report on automating the Catani-Seymour dipole subtraction which is a general procedure to treat infrared divergences in real emission processes at next-to-leading order in QCD. The automatization rests on three essential steps: the creation of the dipole terms, the calculation of the color linked squared Born matrix elements, and the evaluation of different helicity amplitudes. The routines have been tested for a number of complex processes, such as the real emission process gg→t anti tggg. (orig.)

Improvement of Dimensional Accuracy of 3-D Printed Parts using an Additive/Subtractive Based Hybrid Prototyping Approach

Science.gov (United States)

Amanullah Tomal, A. N. M.; Saleh, Tanveer; Raisuddin Khan, Md.

2017-11-01

At present, two important processes, namely CNC machining and rapid prototyping (RP) are being used to create prototypes and functional products. Combining both additive and subtractive processes into a single platform would be advantageous. However, there are two important aspects need to be taken into consideration for this process hybridization. First is the integration of two different control systems for two processes and secondly maximizing workpiece alignment accuracy during the changeover step. Recently we have developed a new hybrid system which incorporates Fused Deposition Modelling (FDM) as RP Process and CNC grinding operation as subtractive manufacturing process into a single setup. Several objects were produced with different layer thickness for example 0.1 mm, 0.15 mm and 0.2 mm. It was observed that pure FDM method is unable to attain desired dimensional accuracy and can be improved by a considerable margin about 66% to 80%, if finishing operation by grinding is carried out. It was also observed layer thickness plays a role on the dimensional accuracy and best accuracy is achieved with the minimum layer thickness (0.1 mm).

Single-Site Palladium(II) Catalyst for Oxidative Heck Reaction: Catalytic Performance and Kinetic Investigations

Energy Technology Data Exchange (ETDEWEB)

Duan, Hui; Li, Mengyang; Zhang, Guanghui; Gallagher, James R.; Huang, Zhiliang; Sun, Yu; Luo, Zhong; Chen, Hongzhong; Miller, Jeffrey T.; Zou, Ruqiang; Lei, Aiwen; Zhao, Yanli

2015-01-01

ABSTRACT: The development of organometallic single-site catalysts (SSCs) has inspired the designs of new heterogeneous catalysts with high efficiency. Nevertheless, the application of SSCs in certain modern organic reactions, such as C-C bond formation reactions, has still been less investigated. In this study, a single-site Pd(II) catalyst was developed, where 2,2'-bipyridine-grafted periodic mesoporous organosilica (PMO) was employed as the support of a Pd(II) complex. The overall performance of the single-site Pd(II) catalyst in the oxidative Heck reaction was then investigated. The investigation results show that the catalyst displays over 99% selectivity for the product formation with high reaction yield. Kinetic profiles further confirm its high catalytic efficiency, showing that the rate constant is nearly 40 times higher than that for the free Pd(II) salt. X-ray absorption spectroscopy reveals that the catalyst has remarkable lifetime and recyclability.

Nonenhanced magnetic resonance angiography (MRA) of the calf arteries at 3 Tesla: intraindividual comparison of 3D flow-dependent subtractive MRA and 2D flow-independent non-subtractive MRA.

Science.gov (United States)

Knobloch, Gesine; Lauff, Marie-Teres; Hirsch, Sebastian; Schwenke, Carsten; Hamm, Bernd; Wagner, Moritz

2016-12-01

To prospectively compare 3D flow-dependent subtractive MRA vs. 2D flow-independent non-subtractive MRA for assessment of the calf arteries at 3 Tesla. Forty-two patients with peripheral arterial occlusive disease underwent nonenhanced MRA of calf arteries at 3 Tesla with 3D flow-dependent subtractive MRA (fast spin echo sequence; 3D-FSE-MRA) and 2D flow-independent non-subtractive MRA (balanced steady-state-free-precession sequence; 2D-bSSFP-MRA). Moreover, all patients underwent contrast-enhanced MRA (CE-MRA) as standard-of-reference. Two readers performed a per-segment evaluation for image quality (4 = excellent to 0 = non-diagnostic) and severity of stenosis. Image quality scores of 2D-bSSFP-MRA were significantly higher compared to 3D-FSE-MRA (medians across readers: 4 vs. 3; p Tesla with significantly higher image quality and diagnostic accuracy compared to 3D flow-dependent subtractive MRA (3D-FSE-MRA). • 2D flow-independent non-subtractive MRA (2D-bSSFP-MRA) is a robust NE-MRA technique at 3T • 2D-bSSFP-MRA outperforms 3D flow-dependent subtractive MRA (3D-FSE-MRA) as NE-MRA of calf arteries • 2D-bSSFP-MRA is a promising alternative to CE-MRA for calf PAOD evaluation.

Digital subtraction angiography (DSA)

International Nuclear Information System (INIS)

Ludwig, J.W.; Eikelboom, B.C.; Van Schaik, C.C.; Taams, A.J.; Teeuwen, C.

1985-01-01

Besides the non-invasive techniques, angiography remains essential. The disadvantages of angiography are the complexity of the procedure and the possibility of complications. Digital subtraction angiography (DSA) is a considerable improvement in the examination of vessels. In DSA, subtraction combined with enhancement of the signals allows the use of intravenous injection to obtain good images of the arteries. However, when the contrast material is supplied intravenously, a rather large amount of contrast material is necessary to obtain images of good quality. Quantities of 30-40 cc of contrast material are required. The advantage of the intravenous injection of contrast material rather than the use of a catheter to deliver the contrast material in loco is that it is almost non-invasive thus circumventing the complications caused by catheter manipulation in the arterial system. This makes it possible to apply this method on an out-patient basis. DSA can also be applied with intra-arterial selective injection of the contrast material. In this case, the strong enhancement with DSA allows the use of a small quantity of contrast material while still obtaining images of the vessels with good contrast definition

Single cell subtractive transcriptomics for identification of cell-specifically expressed candidate genes of pyrrolizidine alkaloid biosynthesis.

Science.gov (United States)

Sievert, Christian; Beuerle, Till; Hollmann, Julien; Ober, Dietrich

2015-09-01

Progress has recently been made in the elucidation of pathways of secondary metabolism. However, because of its diversity, genetic information concerning biosynthetic details is still missing for many natural products. This is also the case for the biosynthesis of pyrrolizidine alkaloids. To close this gap, we tested strategies using tissues that express this pathway in comparison to tissues in which this pathway is not expressed. As many pathways of secondary metabolism are known to be induced by jasmonates, the pyrrolizidine alkaloid-producing species Heliotropium indicum, Symphytum officinale, and Cynoglossum officinale of the Boraginales order were treated with methyl jasmonate. An effect on pyrrolizidine alkaloid levels and on transcript levels of homospermidine synthase, the first specific enzyme of pyrrolizidine alkaloid biosynthesis, was not detectable. Therefore, a method was developed by making use of the often observed cell-specific production of secondary compounds. H. indicum produces pyrrolizidine alkaloids exclusively in the shoot. Homospermidine synthase is expressed only in the cells of the lower leaf epidermis and the epidermis of the stem. Suggesting that the whole pathway of pyrrolizidine alkaloid biosynthesis might be localized in these cells, we have isolated single cells of the upper and lower epidermis by laser-capture microdissection. The resulting cDNA preparations have been used in a subtractive transcriptomic approach. Quantitative real-time polymerase chain reaction has shown that the resulting library is significantly enriched for homospermidine-synthase-coding transcripts providing a valuable source for the identification of further genes involved in pyrrolizidine alkaloid biosynthesis. Copyright © 2015 Elsevier Ltd. All rights reserved.

Subleading power corrections for N -jettiness subtractions

Science.gov (United States)

Moult, Ian; Rothen, Lorena; Stewart, Iain W.; Tackmann, Frank J.; Zhu, Hua Xing

2017-04-01

The N -jettiness observable TN provides a way of describing the leading singular behavior of the N -jet cross section in the τ =TN/Q →0 limit, where Q is a hard interaction scale. We consider subleading-power corrections in the τ ≪1 expansion, and employ soft-collinear effective theory to obtain analytic results for the dominant αsτ ln τ and αs2τ ln3τ subleading terms for thrust in e+e- collisions and 0-jettiness for q q ¯-initiated Drell-Yan-like processes at hadron colliders. These results can be used to significantly improve the numerical accuracy and stability of the N -jettiness subtraction technique for performing fixed-order calculations at next-to-leading order and next-to-next-to-leading order. They reduce the size of missing power corrections in the subtractions by an order of magnitude. We also point out that the precise definition of N -jettiness has an important impact on the size of the power corrections and thus the numerical accuracy of the subtractions. The sometimes employed definition of N -jettiness in the hadronic center-of-mass frame suffers from power corrections that grow exponentially with rapidity, causing the power expansion to deteriorate away from central rapidity. This degradation does not occur for the original N -jettiness definition, which explicitly accounts for the boost of the Born process relative to the frame of the hadronic collision, and has a well-behaved power expansion throughout the entire phase space. Integrated over rapidity, using this N -jettiness definition in the subtractions yields another order of magnitude improvement compared to employing the hadronic-frame definition.

Physical principles of cardiac digital subtraction angiography

International Nuclear Information System (INIS)

Buonocore, E.; Pavlicek, W.

1986-01-01

Advances in the applications of computers with standard radiologic equipment have resulted in the development of electronic, or so-called ''film-less'' imaging. This technique, discussed by the authors, has become of particular value in the visualization of the central vascular system and has become known as digital subtraction angiography (DSA). Commercial products have become increasingly available and are capable of converting T.V. signals, obtained by conventional fluorography, to a computed array of digital values. Addition, subtraction, and averaging of this data, result in images with adequate signal-to-noise ratios that achieve detection of low concentrations of contrast media not possible with conventional screen film techniques. Computer subtraction of unnecessary background information improves the conspicuity of the opacified vessels to permit detection of vascular structures containing a concentration of no more than 1-3 percent of contrast media. This improved visualization is possible even with intravenous peripheral injections or reduced amounts of contrast media given intraarterially. With either method of contrast media administration, DSDA has become an excellent means of anatomic demonstration of the heart and great vessels with decreased morbidity and at lower cost

Probabilistic Model-based Background Subtraction

DEFF Research Database (Denmark)

Krüger, Volker; Anderson, Jakob; Prehn, Thomas

2005-01-01

is the correlation between pixels. In this paper we introduce a model-based background subtraction approach which facilitates prior knowledge of pixel correlations for clearer and better results. Model knowledge is being learned from good training video data, the data is stored for fast access in a hierarchical...

M-BAND IMAGING OF THE HR 8799 PLANETARY SYSTEM USING AN INNOVATIVE LOCI-BASED BACKGROUND SUBTRACTION TECHNIQUE

International Nuclear Information System (INIS)

Galicher, Raphael; Marois, Christian; Macintosh, Bruce; Konopacky, Quinn; Barman, Travis

2011-01-01

Multi-wavelength observations/spectroscopy of exoplanetary atmospheres are the basis of the emerging exciting field of comparative exoplanetology. The HR 8799 planetary system is an ideal laboratory to study our current knowledge gap between massive field brown dwarfs and the cold 5 Gyr old solar system planets. The HR 8799 planets have so far been imaged at J- to L-band, with only upper limits available at M-band. We present here deep high-contrast Keck II adaptive optics M-band observations that show the imaging detection of three of the four currently known HR 8799 planets. Such detections were made possible due to the development of an innovative LOCI-based background subtraction scheme that is three times more efficient than a classical median background subtraction for Keck II AO data, representing a gain in telescope time of up to a factor of nine. These M-band detections extend the broadband photometric coverage out to ∼5 μm and provide access to the strong CO fundamental absorption band at 4.5 μm. The new M-band photometry shows that the HR 8799 planets are located near the L/T-type dwarf transition, similar to what was found by other studies. We also confirm that the best atmospheric fits are consistent with low surface gravity, dusty, and non-equilibrium CO/CH 4 chemistry models.

Digital image comparison by subtracting contextual transformations—percentile rank order differentiation

Science.gov (United States)

Wehde, M. E.

1995-01-01

The common method of digital image comparison by subtraction imposes various constraints on the image contents. Precise registration of images is required to assure proper evaluation of surface locations. The attribute being measured and the calibration and scaling of the sensor are also important to the validity and interpretability of the subtraction result. Influences of sensor gains and offsets complicate the subtraction process. The presence of any uniform systematic transformation component in one of two images to be compared distorts the subtraction results and requires analyst intervention to interpret or remove it. A new technique has been developed to overcome these constraints. Images to be compared are first transformed using the cumulative relative frequency as a transfer function. The transformed images represent the contextual relationship of each surface location with respect to all others within the image. The process of differentiating between the transformed images results in a percentile rank ordered difference. This process produces consistent terrain-change information even when the above requirements necessary for subtraction are relaxed. This technique may be valuable to an appropriately designed hierarchical terrain-monitoring methodology because it does not require human participation in the process.

Late iodine enhancement computed tomography with image subtraction for assessment of myocardial infarction

Energy Technology Data Exchange (ETDEWEB)

Tanabe, Yuki; Kido, Teruhito; Kurata, Akira; Kouchi, Takanori; Fukuyama, Naoki; Yokoi, Takahiro; Miyagawa, Masao; Mochizuki, Teruhito [Ehime University Graduate School of Medicine, Department of Radiology, Toon City, Ehime (Japan); Uetani, Teruyoshi [Department of Cardiology, Ehime University Graduate School of Medicine, Toon City, Ehime (Japan); Yamashita, Natsumi [National Hospital Organization Shikoku Cancer Center, Department of Clinical Biostatistics, Section of Cancer Prevention and Epidemiology, Clinical Research Center, Matsuyama City, Ehime (Japan)

2018-03-15

To evaluate the feasibility of image subtraction in late iodine enhancement CT (LIE-CT) for assessment of myocardial infarction (MI). A comprehensive cardiac CT protocol and late gadolinium enhancement MRI (LGE-MRI) was used to assess coronary artery disease in 27 patients. LIE-CT was performed after stress CT perfusion (CTP) and CT angiography. Subtraction LIE-CT was created by subtracting the mask volume of the left ventricle (LV) cavity from the original LIE-CT using CTP dataset. The %MI volume was quantified as the ratio of LIE to entire LV volume, and transmural extent (TME) of LIE was classified as 0%, 1-24%, 25-49%, 50-74% or 75-100%. These results were compared with LGE-MRI using the Spearman rank test, Bland-Altman method and chi-square test. One hundred twenty-five (29%) of 432 segments were positive on LGE-MRI. Correlation coefficients for original and subtraction LIE-CT to LGE-MRI were 0.79 and 0.85 for %MI volume. Concordances of the 5-point grading scale between original and subtraction LIE-CT with LGE-MRI were 75% and 84% for TME; concordance was significantly improved using the subtraction technique (p <0.05). Subtraction LIE-CT allowed more accurate assessment of MI extent than the original LIE-CT. (orig.)

Decoupling Subtraction Conserving Full Gauge Symmetries : Particles and Fields

OpenAIRE

Noriyasu, OHTSUBO; Hideo, MIYATA; Department of Phycics, Kanazawa Technical College; Department of Information Science, Kanazawa Institute of Technolgy

1984-01-01

A new subtraction scheme (^^^) which realizes the decoupling and conserves the symmetries of full gauge group simultaneously, is proposed. One particle irreducible Green's functions subtracted by ^^^ reveal the effective low energy symmetries at -p^2≪M^2 and the full symmetries at -p^2≫M^2, where M denotes a heavy mass. Also discussed are conditions in order to carry out ^^^ under two-loop approximation.

Digital subtraction radiography in the study of the lacrimal system

International Nuclear Information System (INIS)

Falaschi, F.; Pieri, L.; Perri, G.; Signorini, G.; Genovese Ebert, F.

1988-01-01

The authors emphasize the usefulness of digital dacrycystography (DCG), as compared with various current technoques. Utilizing a radiographic unit equipped with a video-fluoroscopic system and interfaced to a digital video-processor, several digitalized images are acquired before, during and after the injection of contrast medium. Final images are obtained by subtraction of suitable pairs of source frames. Twenty-six patients affected by epiphora have been examined so far. In 21 cases digital subtraction DCG allowed an accurate visualization of the lacrimal system; in the other five patients the amount of information was acceptable. This methodology allows the assessment of both the normal anatomy of the lacrimal passages and their pathological patterns, such as obstructions, stenoses, fistulas, chronic dacrycystites, lacrimal stones. The examination is easy and quick to perform, with no discomfort for the patient. Digital subtraction DCG proves thus to be a very valuable technique thanks to its possible electronic elaboration - i.e. the subtraction and the magnification of images - to its better contrast resolution, and to the possibility it yields of dynamic studies under radioscopic control

Detection of intracranial aneurysms using three-dimensional multidetector-row CT angiography: Is bone subtraction necessary?

International Nuclear Information System (INIS)

Hwang, Seung Bae; Kwak, Hyo Sung; Han, Young Min; Chung, Gyung Ho

2011-01-01

Purpose: The aim of this study was to evaluate the usefulness of three-dimensional CT angiography (3D CTA) with bone subtraction in a comparison with 3D CTA without bone subtraction for the detection of intracranial aneurysms. Materials and methods: Among 337 consecutive patients who had intracranial aneurysms detected on 3D CTA, 170 patients who underwent digital subtraction angiography (DSA) were included in the study. CTA was performed with a 16-slice multidetector-row CT (MDCT) scanner. We created the 3D reconstruction images with and without bone subtraction by using the volume rendering technique. Three neuroradiologists in a blinded fashion interpreted both 3D CTA images with and without bone subtraction. The diagnostic accuracy of both techniques was evaluated using the alternative free-response receiver operating characteristic (ROC) analysis. The sensitivity and positive predictive value were also evaluated. Results: A total of 200 aneurysms (size: 2-23 mm) were detected in 170 patients. The area under the receiver operating characteristic curve (Az) for 3D CTA with bone subtraction (mean, Az = 0.933) was significantly higher than that for 3D CTA without bone subtraction (mean, Az = 0.879) for all observers (P < 0.05). The sensitivity of 3D CTA with bone subtraction for three observers was 90.0, 92.0 and 92.5%, respectively, while the sensitivity of 3D CTA without bone subtraction was 83.5, 83.5 and 87.5%, respectively. No significant difference in positive predictive value was observed between the two modalities. Conclusions: 3D CTA with bone subtraction showed significantly higher diagnostic accuracy for the detection of intracranial aneurysms as compared to 3D CTA without bone subtraction.

Incidence of ischemic lesions in diffusion-weighted imaging after transbrachial digital subtraction angiography

International Nuclear Information System (INIS)

Aschenbach, R.; Majeed, A.; Eger, C.; Basche, S.; Kerl, J.M.; Vogl, T.J.

2008-01-01

Purpose: to evaluate the frequency of ischemia after transbrachial digital subtraction angiography under ambulant conditions using diffusion-weighted imaging. Materials and methods: 200 patients were included in a prospective study design and received transbrachial digital subtraction angiography under ambulant conditions. Before and after digital subtraction angiography, diffusion-weighted imaging of the brain was performed. Results: in our study population no new lesions were found in diffusion-weighted imaging after digital subtraction angiography during the 3-hour window after angiography. One new lesion was found 3 days after angiography as a late onset complication. Therefore, the frequency of neurological complications is at the level of the confidence interval of 0 - 1.5%. Conclusion: the transbrachial approach under ambulant conditions is a safe method for digital subtraction angiography resulting in a low rate of ischemic lesions in diffusion-weighted imaging. (orig.)

Digital subtraction angiography in traumatology

International Nuclear Information System (INIS)

Steudel, A.; Harder, T.; Lackner, K.; Schneider, B.; Orellano, L.; Bonn Univ.; Bonn Univ.

1986-01-01

The methods, indications and results of digital subtraction angiography in traumatology are presented, based on 56 examinations. The different use of intravenous or intraarterial DSA will be discussed with respect to expanding and localisation of traumatic vascular injury. DSA is recommended as the method of choice for follow-up after vascular reconstructive procedure. (orig.) [de

Subtractive Structural Modification of Morpho Butterfly Wings.

Science.gov (United States)

Shen, Qingchen; He, Jiaqing; Ni, Mengtian; Song, Chengyi; Zhou, Lingye; Hu, Hang; Zhang, Ruoxi; Luo, Zhen; Wang, Ge; Tao, Peng; Deng, Tao; Shang, Wen

2015-11-11

Different from studies of butterfly wings through additive modification, this work for the first time studies the property change of butterfly wings through subtractive modification using oxygen plasma etching. The controlled modification of butterfly wings through such subtractive process results in gradual change of the optical properties, and helps the further understanding of structural optimization through natural evolution. The brilliant color of Morpho butterfly wings is originated from the hierarchical nanostructure on the wing scales. Such nanoarchitecture has attracted a lot of research effort, including the study of its optical properties, its potential use in sensing and infrared imaging, and also the use of such structure as template for the fabrication of high-performance photocatalytic materials. The controlled subtractive processes provide a new path to modify such nanoarchitecture and its optical property. Distinct from previous studies on the optical property of the Morpho wing structure, this study provides additional experimental evidence for the origination of the optical property of the natural butterfly wing scales. The study also offers a facile approach to generate new 3D nanostructures using butterfly wings as the templates and may lead to simpler structure models for large-scale man-made structures than those offered by original butterfly wings. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Safety of Diagnostic Cerebral and Spinal Digital Subtraction Angiography in a Developing Country: A Single-Center Experience.

Science.gov (United States)

Bashir, Qasim; Ishfaq, Asim; Baig, Ammad Anwar

2018-02-01

Digital subtraction angiography (DSA) remains the gold standard imaging modality for cerebrovascular disorders. In contrast to developed countries, the safety of the procedure is not extensively reported from the developing countries. Herein, we present a retrospective analysis of the basic technique, indications, and outcomes in 286 patients undergoing diagnostic cerebral and spinal angiography in a developing country, Pakistan. A retrospective review of patient demographics, procedural technique and complication rates of 286 consecutive patients undergoing the diagnostic cerebral/spinal angiography procedure at one institution from May 2013 to December 2015 was performed. Neurological, systemic, or local complications occurring within and after 24 h of the procedure were recorded. Mean age reported for all patients was 49.7 years. Of all the 286 cases, 175 were male (61.2%) and the rest female (111, 38.8%). Cerebral DSA was performed in 279 cases (97.6%), with 7 cases of spinal DSA (2.4%). Subarachnoid hemorrhage was the most common indication for DSA accounting for 88 cases (30.8%), closely followed by stroke (26.6%) and arteriosclerotic vascular disease (23.1%). No intra- or post-procedural neurological complications of any severity were seen in any of the 286 cases. One case of asymptomatic aortic dissection was reported (0.3%) in the entire cohort of patient population. Diagnostic cerebral/spinal digital subtraction angiography was found to be safe in Pakistan, with complication rates at par with and comparable to those reported in the developed world.

Digital subtraction angiography: first 900 cases

International Nuclear Information System (INIS)

Rodgers, H.

1984-01-01

The diagnostic technique of digital subtraction angiography (DSA) is briefly outlined. The operational and technical experiences with a DR-960 DSA system used in the examination of the first 900 cases at St. Thomas' Hospital, London are described. (U.K.)

Thallium-201 and technetium-99m pertechnetate subtraction scintigraphy in patients with hyperparathyroidism

International Nuclear Information System (INIS)

Kuwashima, Shigeko; Koizumi, Mitsuru; Goto, Masafumi; Nomura, Toshiharu; Fujioka, Mutsuhisa; Watari, Tsutomu

1992-01-01

A reliable technique for detecting and localizing abnormal parathyroid tissue has been a persistent problem. We evaluated thallium-technetium (Tl/Tc) subtraction scintigraphy in 16 patients with clinical biochemical evidence of hyperparathyroidism prior to other diagnostic methods and surgery. Seven patients had surgery and were confirmed to have parathyroid adenoma or hyperplasia. The other methods included ultrasonography (US) in 6 patients, computed tomography (CT) in 10 patients, magnetic resonance imaging (MRI) in 8 patients, and bone scintigraphy in 7 patients. In patients who had several imaging modalities, the detection rate was significantly better for Tl/Tc subtraction scan than for US, CT or MRI. Bote scintigraphy, though not so sensitive as Tl/Tc subtraction studies, was an important tool for evaluating metabolic bone disorder including hyperparathyroidism and renal osteodystrophy. Thus, Tl/Tc subtraction scan is more useful for diagnosis when hyperparathyroidism is suspected if both Tl/Tc subtraction scan and bone scan are performed. The detectability depended on the mass size, and detection of abnormal glands was greater for adenoma than for hyperplasia. The results suggest that Tl/Tc subtraction scan is a simple, non-invasive and useful tool for locating parathyroid abnormality even when compared with MRI. (author)

Color Addition and Subtraction Apps

Science.gov (United States)

Ruiz, Frances; Ruiz, Michael J.

2015-01-01

Color addition and subtraction apps in HTML5 have been developed for students as an online hands-on experience so that they can more easily master principles introduced through traditional classroom demonstrations. The evolution of the additive RGB color model is traced through the early IBM color adapters so that students can proceed step by step…

Power corrections in the N-jettiness subtraction scheme

Energy Technology Data Exchange (ETDEWEB)

Boughezal, Radja [High Energy Physics Division, Argonne National Laboratory,Argonne, IL 60439 (United States); Liu, Xiaohui [Department of Physics, Beijing Normal University,Beijing, 100875 (China); Center of Advanced Quantum Studies, Beijing Normal University,Beijing, 100875 (China); Center for High-Energy Physics, Peking University,Beijing, 100871 (China); Maryland Center for Fundamental Physics, University of Maryland,College Park, MD 20742 (United States); Petriello, Frank [Department of Physics & Astronomy, Northwestern University,Evanston, IL 60208 (United States); High Energy Physics Division, Argonne National Laboratory,Argonne, IL 60439 (United States)

2017-03-30

We discuss the leading-logarithmic power corrections in the N-jettiness subtraction scheme for higher-order perturbative QCD calculations. We compute the next-to-leading order power corrections for an arbitrary N-jet process, and we explicitly calculate the power correction through next-to-next-to-leading order for color-singlet production for both qq̄ and gg initiated processes. Our results are compact and simple to implement numerically. Including the leading power correction in the N-jettiness subtraction scheme substantially improves its numerical efficiency. We discuss what features of our techniques extend to processes containing final-state jets.

A simple digital subtraction angiographic instrument

International Nuclear Information System (INIS)

Ando, Hiroshi; Kobayashi, Tsuyoshi; Imai, Yutaka; Yanagishita, Akira

1983-01-01

A digital subtraction angiographic instrument was manufactured using a conventional x-ray TV for gastrointestinal series and a computer for processing of nuclear medical data. The results of visualization of the aorta and its primary branches were reviewed with demonstrable cases. (Chiba, N.)

Summation and subtraction using a modified autoshaping procedure in pigeons.

Science.gov (United States)

Ploog, Bertram O

2008-06-01

A modified autoshaping paradigm (significantly different from those previously reported in the summation literature) was employed to allow for the simultaneous assessment of stimulus summation and subtraction in pigeons. The response requirements and the probability of food delivery were adjusted such that towards the end of training 12 of 48 trials ended in food delivery, the same proportion as under testing. Stimuli (outlines of squares of three sizes and colors: A, B, and C) were used that could be presented separately or in any combination of two or three stimuli. Twelve of the pigeons (summation groups) were trained with either A, B, and C or with AB, BC, and CA, and tested with ABC. The remaining 12 pigeons (subtraction groups) received training with ABC but were tested with A, B, and C or with AB, BC, and CA. These groups were further subdivided according to whether stimulus elements were presented either in a concentric or dispersed manner. Summation did not occur; subtraction occurred in the two concentric groups. For interpretation of the results, configural theory, the Rescorla-Wagner model, and the composite-stimulus control model were considered. The results suggest different mechanisms responsible for summation and subtraction.

The spectrum of singly ionized oxygen, O II

International Nuclear Information System (INIS)

Wenaker, I.

1990-01-01

The spectrum of singly ionized oxygen, O II, emitted by a spark-generated, electrodeless discharge light source, has been investigated in the wavelength range 2100-11700 A. About 740 lines, 359 of which have not been reported earlier, were measured. As a result the energies of about 50 new levels have been determined, and the O II term system now presented includes 254 levels. The quartet system is firmly connected to the doublet system by 56 identified intersystem lines. The ionization limits have been determined by applying the polarization formula to the 4f, 5f, 5g and 6g levels. The experimentally determined value for the lowest limit, 2s 2 2p 2 3 P 0 , is 283270.9±0.5 cm -1 above the 2s 2 2p 3 4 S 3/2 ground state. (orig.)

Appearance of the canine meninges in subtraction magnetic resonance images.

Science.gov (United States)

Lamb, Christopher R; Lam, Richard; Keenihan, Erin K; Frean, Stephen

2014-01-01

The canine meninges are not visible as discrete structures in noncontrast magnetic resonance (MR) images, and are incompletely visualized in T1-weighted, postgadolinium images, reportedly appearing as short, thin curvilinear segments with minimal enhancement. Subtraction imaging facilitates detection of enhancement of tissues, hence may increase the conspicuity of meninges. The aim of the present study was to describe qualitatively the appearance of canine meninges in subtraction MR images obtained using a dynamic technique. Images were reviewed of 10 consecutive dogs that had dynamic pre- and postgadolinium T1W imaging of the brain that was interpreted as normal, and had normal cerebrospinal fluid. Image-anatomic correlation was facilitated by dissection and histologic examination of two canine cadavers. Meningeal enhancement was relatively inconspicuous in postgadolinium T1-weighted images, but was clearly visible in subtraction images of all dogs. Enhancement was visible as faint, small-rounded foci compatible with vessels seen end on within the sulci, a series of larger rounded foci compatible with vessels of variable caliber on the dorsal aspect of the cerebral cortex, and a continuous thin zone of moderate enhancement around the brain. Superimposition of color-encoded subtraction images on pregadolinium T1- and T2-weighted images facilitated localization of the origin of enhancement, which appeared to be predominantly dural, with relatively few leptomeningeal structures visible. Dynamic subtraction MR imaging should be considered for inclusion in clinical brain MR protocols because of the possibility that its use may increase sensitivity for lesions affecting the meninges. © 2014 American College of Veterinary Radiology.

IR subtraction schemes. Integrating the counterterms at NNLO in QCD

Energy Technology Data Exchange (ETDEWEB)

Bolzoni, Paolo; Somogyi, Gabor

2010-06-15

We briefly review a subtraction scheme for computing radiative corrections to QCD jet cross sections that can be defined at any order in perturbation theory. Hereafter we discuss the computational methods used to evaluate analytically and numerically the integrated counterterms arising from such a subtraction scheme. Basically these methods the Mellin-Barnes (MB) representations technique together with the harmonic summation and the sector decomposition. (orig.)

IR subtraction schemes. Integrating the counterterms at NNLO in QCD

International Nuclear Information System (INIS)

Bolzoni, Paolo; Somogyi, Gabor

2010-06-01

We briefly review a subtraction scheme for computing radiative corrections to QCD jet cross sections that can be defined at any order in perturbation theory. Hereafter we discuss the computational methods used to evaluate analytically and numerically the integrated counterterms arising from such a subtraction scheme. Basically these methods the Mellin-Barnes (MB) representations technique together with the harmonic summation and the sector decomposition. (orig.)

Digital subtraction arthrography in preoperative evaluation of painful total hip arthroplasty

International Nuclear Information System (INIS)

Ginai, A.Z.; Biezen, F.C. van; Kint, P.A.M.; Oei, H.Y.; Hop, W.C.J.

1996-01-01

Digital subtraction arthrograms, scintigrams and plain radiographs of 70 consecutive patients who underwent revision hip arthroplasty were scored individually and in masked fashion for the presence or absence of features indicating loosening of femoral and/or acetabular components. The operative findings acted as the gold standard. Digital subtraction arthrography was best for predicting a loose acetabular component, while no significant additional predictive value was found for plain radiographs and scintigraphy. Digital subtraction arthrography was also the most important modality for predicting a loose femoral component, while the plain radiograph was of significant additional value and scintigraphy was of no additional value on multivariate analysis. (orig./MG)

3D temporal subtraction on multislice CT images using nonlinear warping technique

Science.gov (United States)

Ishida, Takayuki; Katsuragawa, Shigehiko; Kawashita, Ikuo; Kim, Hyounseop; Itai, Yoshinori; Awai, Kazuo; Li, Qiang; Doi, Kunio

2007-03-01

The detection of very subtle lesions and/or lesions overlapped with vessels on CT images is a time consuming and difficult task for radiologists. In this study, we have developed a 3D temporal subtraction method to enhance interval changes between previous and current multislice CT images based on a nonlinear image warping technique. Our method provides a subtraction CT image which is obtained by subtraction of a previous CT image from a current CT image. Reduction of misregistration artifacts is important in the temporal subtraction method. Therefore, our computerized method includes global and local image matching techniques for accurate registration of current and previous CT images. For global image matching, we selected the corresponding previous section image for each current section image by using 2D cross-correlation between a blurred low-resolution current CT image and a blurred previous CT image. For local image matching, we applied the 3D template matching technique with translation and rotation of volumes of interests (VOIs) which were selected in the current and the previous CT images. The local shift vector for each VOI pair was determined when the cross-correlation value became the maximum in the 3D template matching. The local shift vectors at all voxels were determined by interpolation of shift vectors of VOIs, and then the previous CT image was nonlinearly warped according to the shift vector for each voxel. Finally, the warped previous CT image was subtracted from the current CT image. The 3D temporal subtraction method was applied to 19 clinical cases. The normal background structures such as vessels, ribs, and heart were removed without large misregistration artifacts. Thus, interval changes due to lung diseases were clearly enhanced as white shadows on subtraction CT images.

High fidelity nanopatterning of proteins onto well-defined surfaces through subtractive contact printing.

Science.gov (United States)

García, José R; Singh, Ankur; García, Andrés J

2014-01-01

In the pursuit to develop enhanced technologies for cellular bioassays as well as understand single cell interactions with its underlying substrate, the field of biotechnology has extensively utilized lithographic techniques to spatially pattern proteins onto surfaces in user-defined geometries. Microcontact printing (μCP) remains an incredibly useful patterning method due to its inexpensive nature, scalability, and the lack of considerable use of specialized clean room equipment. However, as new technologies emerge that necessitate various nano-sized areas of deposited proteins, traditional μCP methods may not be able to supply users with the needed resolution size. Recently, our group developed a modified "subtractive μCP" method which still retains many of the benefits offered by conventional μCP. Using this technique, we have been able to reach resolution sizes of fibronectin as small as 250 nm in largely spaced arrays for cell culture. In this communication, we present a detailed description of our subtractive μCP procedure that expands on many of the little tips and tricks that together make this procedure an easy and effective method for controlling protein patterning. © 2014 Elsevier Inc. All rights reserved.

The Use of Procedural Knowledge in Simple Addition and Subtraction Problems

Science.gov (United States)

Fayol, Michel; Thevenot, Catherine

2012-01-01

In a first experiment, adults were asked to solve one-digit additions, subtractions and multiplications. When the sign appeared 150 ms before the operands, addition and subtraction were solved faster than when the sign and the operands appeared simultaneously on screen. This priming effect was not observed for multiplication problems. A second…

Temporal subtraction of chest radiographs compensating pose differences

Science.gov (United States)

von Berg, Jens; Dworzak, Jalda; Klinder, Tobias; Manke, Dirk; Kreth, Adrian; Lamecker, Hans; Zachow, Stefan; Lorenz, Cristian

2011-03-01

Temporal subtraction techniques using 2D image registration improve the detectability of interval changes from chest radiographs. Although such methods are well known for some time they are not widely used in radiologic practice. The reason is the occurrence of strong pose differences between two acquisitions with a time interval of months to years in between. Such strong perspective differences occur in a reasonable number of cases. They cannot be compensated by available image registration methods and thus mask interval changes to be undetectable. In this paper a method is proposed to estimate a 3D pose difference by the adaptation of a 3D rib cage model to both projections. The difference between both is then compensated for, thus producing a subtraction image with virtually no change in pose. The method generally assumes that no 3D image data is available from the patient. The accuracy of pose estimation is validated with chest phantom images acquired under controlled geometric conditions. A subtle interval change simulated by a piece of plastic foam attached to the phantom becomes visible in subtraction images generated with this technique even at strong angular pose differences like an anterior-posterior inclination of 13 degrees.

Wilson expansion in the minimal subtraction scheme

International Nuclear Information System (INIS)

Smirnov, V.A.

1989-01-01

The small distance expansion of the product of composite fields is constructed for an arbitrary renormalization procedure of the type of minimal subtraction scheme. Coefficient functions of the expansion are expressed explicitly through the Green functions of composite fields. The expansion has the explicity finite form: the ultraviolet (UV) divergences of the coefficient functions and composite fields are removed by the initial renormalization procedure while the infrared (IR) divergences in massless diagrams with nonvanishing contribution into the coefficient functions are removed by the R-operation which is the IR part of the R-operation. The latter is the generalization of the dimensional renormalization in the case when both UV and IR divergences are present. To derive the expansion, a ''pre-subtracting operator'' is introduced and formulas of the counter-term technique are exploited

Revised analysis of singly ionized xenon, Xe II

International Nuclear Information System (INIS)

Hansen, J.E.; Persson, W.

1987-01-01

We present a revised analysis of the spectrum of singly ionized xenon, Xe II. This spectrum has been reanalyzed on the basis of the wavelength material published by Drs J. C. Boyce and C. J. Humphreys. The latter has kindly placed the original wavelength list covering the wavelength range 10220-390 A at our disposal. We report 161 energy levels which have been identified on the basis of classifications of 950 lines. We report first f and g levels in Xe II. Also a number of g-factors have been determined for the first time and we give in total 75 g-factors. We have carried out least-squares fits to the even configurations and report the resulting parameter values and eigenvector compositions. A least-squares fit to the 5p 4 6p configuration is also reported. The levels have been named in jK and for many levels also in LS coupling. The former is the better coupling scheme for Xe II. We present an analysis of the 5s photoelectron satellite spectrum of Xe based on our calculated eigenvector compositions and calculations of transition probabilities for ground state transitions as well as lifetimes for the 6p levels. The latter are compared to recent experimental measurements. A list of wavelengths for observed laser transitions showing the present classifications and a discussion of the determination of the ionization potential of Xe II concludes the paper. (orig.)

Dynamic contrast-enhanced subtraction MR angiography in intracranial vascular abnormalities

International Nuclear Information System (INIS)

Takano, K.; Ono, H.; Utsunomiya, H.; Okazaki, M.; Tanaka, A.

1999-01-01

We present our clinical experience with dynamic contrast-enhanced MR angiography (MRA) with subtraction for assessing intracranial vascular abnormalities. Ten patients with various cerebrovascular disorders underwent dynamic contrast-enhanced MRA on a 1.0-T system. Thirty sections (2 mm) were acquired in 29-30 s. Maximum intensity projection images and subtracted source images were compared with those obtained by conventional angiography. In all cases, the presence or absence of abnormalities in the targeted vessels, as well as the morphology of the sagittal sinuses, was clearly visualized as in conventional angiography, without any obstructions such as hyperintense hematomas or thrombi, or intraluminal turbulence. Although the temporal and spatial resolutions with current hardware are insufficient, these preliminary results suggest that dynamic contrast-enhanced MRA with subtraction may be useful for assessing vascular lesions with hemorrhage or thrombus, and the dural sinuses. (orig.)

Entdeckung elektroschwacher Produktion einzelner Top-Quarks mit dem CDF II Experiment; Discovery electroweak production of single top quarks with the CDF II Experiment

Energy Technology Data Exchange (ETDEWEB)

Luck, Jan [Karlsruhe Inst. of Technology (KIT) (Germany)

2009-01-01

This thesis presents a neural network search for combined as well as separate s- and t-channel single top-quark production with the CDF II experiment at the Tevatron using 3.2 fb^-1 of collision data. It is the twelfth thesis dealing with single top-quark production performed within the CDF Collaboration, whereas three have been done in Run I [53–55] and eight in Run II [23, 25, 28, 39, 56–59].

A temporal subtraction method for thoracic CT images based on generalized gradient vector flow

International Nuclear Information System (INIS)

Miyake, Noriaki; Kim, H.; Maeda, Shinya; Itai, Yoshinori; Tan, J.K.; Ishikawa, Seiji; Katsuragawa, Shigehiko

2010-01-01

A temporal subtraction image, which is obtained by subtraction of a previous image from a current one, can be used for enhancing interval changes (such as formation of new lesions and changes in existing abnormalities) on medical images by removing most of the normal structures. If image registration is incorrect, not only the interval changes but also the normal structures would be appeared as some artifacts on the temporal subtraction image. In a temporal subtraction technique for 2-D X-ray image, the effectiveness is shown through a lot of clinical evaluation experiments, and practical use is advancing. Moreover, the MDCT (Multi-Detector row Computed Tomography) can easily introduced on medical field, the development of a temporal subtraction for thoracic CT Images is expected. In our study, a temporal subtraction technique for thoracic CT Images is developed. As the technique, the vector fields are described by use of GGVF (Generalized Gradient Vector Flow) from the previous and current CT images. Afterwards, VOI (Volume of Interest) are set up on the previous and current CT image pairs. The shift vectors are calculated by using nearest neighbor matching of the vector fields in these VOIs. The search kernel on previous CT image is set up from the obtained shift vector. The previous CT voxel which resemble standard the current voxel is detected by voxel value and vector of the GGVF in the kernel. And, the previous CT image is transformed to the same coordinate of standard voxel. Finally, temporal subtraction image is made by subtraction of a warping image from a current one. To verify the proposal method, the result of application to 7 cases and the effectiveness are described. (author)

Single Photon Sensitive HgCdTe Avalanche Photodiode Detector (APD), Phase II

Data.gov (United States)

National Aeronautics and Space Administration — Leveraging Phase I SBIR successes, in Phase II, a single photon sensitive LIDAR receiver will be fabricated and delivered to NASA. In Phase I, high-gain,...

Momentum-subtraction renormalization techniques in curved space-time

Energy Technology Data Exchange (ETDEWEB)

Foda, O.

1987-10-01

Momentum-subtraction techniques, specifically BPHZ and Zimmermann's Normal Product algorithm, are introduced as useful tools in the study of quantum field theories in the presence of background fields. In a model of a self-interacting massive scalar field, conformally coupled to a general asymptotically-flat curved space-time with a trivial topology, momentum-subtractions are shown to respect invariance under general coordinate transformations. As an illustration, general expressions for the trace anomalies are derived, and checked by explicit evaluation of the purely gravitational contributions in the free field theory limit. Furthermore, the trace of the renormalized energy-momentum tensor is shown to vanish at the Gell-Mann Low eigenvalue as it should.

Momentum-subtraction renormalization techniques in curved space-time

International Nuclear Information System (INIS)

Foda, O.

1987-01-01

Momentum-subtraction techniques, specifically BPHZ and Zimmermann's Normal Product algorithm, are introduced as useful tools in the study of quantum field theories in the presence of background fields. In a model of a self-interacting massive scalar field, conformally coupled to a general asymptotically-flat curved space-time with a trivial topology, momentum-subtractions are shown to respect invariance under general coordinate transformations. As an illustration, general expressions for the trace anomalies are derived, and checked by explicit evaluation of the purely gravitational contributions in the free field theory limit. Furthermore, the trace of the renormalized energy-momentum tensor is shown to vanish at the Gell-Mann Low eigenvalue as it should

Subtraction with hadronic initial states at NLO: an NNLO-compatible scheme

Science.gov (United States)

Somogyi, Gábor

2009-05-01

We present an NNLO-compatible subtraction scheme for computing QCD jet cross sections of hadron-initiated processes at NLO accuracy. The scheme is constructed specifically with those complications in mind, that emerge when extending the subtraction algorithm to next-to-next-to-leading order. It is therefore possible to embed the present scheme in a full NNLO computation without any modifications.

Subtraction with hadronic initial states at NLO: an NNLO-compatible scheme

International Nuclear Information System (INIS)

Somogyi, Gabor

2009-01-01

We present an NNLO-compatible subtraction scheme for computing QCD jet cross sections of hadron-initiated processes at NLO accuracy. The scheme is constructed specifically with those complications in mind, that emerge when extending the subtraction algorithm to next-to-next-to-leading order. It is therefore possible to embed the present scheme in a full NNLO computation without any modifications.

Continuous-variable measurement-device-independent quantum key distribution with photon subtraction

Science.gov (United States)

Ma, Hong-Xin; Huang, Peng; Bai, Dong-Yun; Wang, Shi-Yu; Bao, Wan-Su; Zeng, Gui-Hua

2018-04-01

It has been found that non-Gaussian operations can be applied to increase and distill entanglement between Gaussian entangled states. We show the successful use of the non-Gaussian operation, in particular, photon subtraction operation, on the continuous-variable measurement-device-independent quantum key distribution (CV-MDI-QKD) protocol. The proposed method can be implemented based on existing technologies. Security analysis shows that the photon subtraction operation can remarkably increase the maximal transmission distance of the CV-MDI-QKD protocol, which precisely make up for the shortcoming of the original CV-MDI-QKD protocol, and one-photon subtraction operation has the best performance. Moreover, the proposed protocol provides a feasible method for the experimental implementation of the CV-MDI-QKD protocol.

Digital subtraction radiography in the study of moving laryngeal structures

International Nuclear Information System (INIS)

Perri, G.; Falaschi, F.; Pieri, L.; Esposito, S.; Ursino, F.

1988-01-01

Digital subtraction radiography (DSR) was applied to the study of the larynx in 11 healthy subjects and 15 pathological cases. The method, consisting in the subtraction of images obtained at rest and during phonation or respiratory phases, allowed a clear definition of the normal moving structures - i.e. vocal cords, false cords, pyriform sinuses, thyroid cartilage. Moreover, several pathological conditions could be demonstrated. DSR asserts thus itself as a suitable technique in the functional evaluation of glottis

A method for dynamic subtraction MR imaging of the liver

Directory of Open Access Journals (Sweden)

Setti Ernesto

2006-06-01

Full Text Available Abstract Background Subtraction of Dynamic Contrast-Enhanced 3D Magnetic Resonance (DCE-MR volumes can result in images that depict and accurately characterize a variety of liver lesions. However, the diagnostic utility of subtraction images depends on the extent of co-registration between non-enhanced and enhanced volumes. Movement of liver structures during acquisition must be corrected prior to subtraction. Currently available methods are computer intensive. We report a new method for the dynamic subtraction of MR liver images that does not require excessive computer time. Methods Nineteen consecutive patients (median age 45 years; range 37–67 were evaluated by VIBE T1-weighted sequences (TR 5.2 ms, TE 2.6 ms, flip angle 20°, slice thickness 1.5 mm acquired before and 45s after contrast injection. Acquisition parameters were optimized for best portal system enhancement. Pre and post-contrast liver volumes were realigned using our 3D registration method which combines: (a rigid 3D translation using maximization of normalized mutual information (NMI, and (b fast 2D non-rigid registration which employs a complex discrete wavelet transform algorithm to maximize pixel phase correlation and perform multiresolution analysis. Registration performance was assessed quantitatively by NMI. Results The new registration procedure was able to realign liver structures in all 19 patients. NMI increased by about 8% after rigid registration (native vs. rigid registration 0.073 ± 0.031 vs. 0.078 ± 0.031, n.s., paired t-test and by a further 23% (0.096 ± 0.035 vs. 0.078 ± 0.031, p t-test after non-rigid realignment. The overall average NMI increase was 31%. Conclusion This new method for realigning dynamic contrast-enhanced 3D MR volumes of liver leads to subtraction images that enhance diagnostic possibilities for liver lesions.

Mental Computation or Standard Algorithm? Children's Strategy Choices on Multi-Digit Subtractions

Science.gov (United States)

Torbeyns, Joke; Verschaffel, Lieven

2016-01-01

This study analyzed children's use of mental computation strategies and the standard algorithm on multi-digit subtractions. Fifty-eight Flemish 4th graders of varying mathematical achievement level were individually offered subtractions that either stimulated the use of mental computation strategies or the standard algorithm in one choice and two…

Nonenhanced magnetic resonance angiography (MRA) of the calf arteries at 3 Tesla: intraindividual comparison of 3D flow-dependent subtractive MRA and 2D flow-independent non-subtractive MRA

Energy Technology Data Exchange (ETDEWEB)

Knobloch, Gesine; Lauff, Marie-Teres; Hirsch, Sebastian; Hamm, Bernd; Wagner, Moritz [Charite - Universitaetsmedizin Berlin, Department of Radiology, Berlin (Germany); Schwenke, Carsten [SCO:SSiS Statistical Consulting, Berlin (Germany)

2016-12-15

To prospectively compare 3D flow-dependent subtractive MRA vs. 2D flow-independent non-subtractive MRA for assessment of the calf arteries at 3 Tesla. Forty-two patients with peripheral arterial occlusive disease underwent nonenhanced MRA of calf arteries at 3 Tesla with 3D flow-dependent subtractive MRA (fast spin echo sequence; 3D-FSE-MRA) and 2D flow-independent non-subtractive MRA (balanced steady-state-free-precession sequence; 2D-bSSFP-MRA). Moreover, all patients underwent contrast-enhanced MRA (CE-MRA) as standard-of-reference. Two readers performed a per-segment evaluation for image quality (4 = excellent to 0 = non-diagnostic) and severity of stenosis. Image quality scores of 2D-bSSFP-MRA were significantly higher compared to 3D-FSE-MRA (medians across readers: 4 vs. 3; p < 0.0001) with lower rates of non-diagnostic vessel segments on 2D-bSSFP-MRA (reader 1: <1 % vs. 15 %; reader 2: 1 % vs. 29 %; p < 0.05). Diagnostic performance of 2D-bSSFP-MRA and 3D-FSE-MRA across readers showed sensitivities of 89 % (214/240) vs. 70 % (168/240), p = 0.0153; specificities: 91 % (840/926) vs. 63 % (585/926), p < 0.0001; and diagnostic accuracies of 90 % (1054/1166) vs. 65 % (753/1166), p < 0.0001. 2D flow-independent non-subtractive MRA (2D-bSSFP-MRA) is a robust nonenhanced MRA technique for assessment of the calf arteries at 3 Tesla with significantly higher image quality and diagnostic accuracy compared to 3D flow-dependent subtractive MRA (3D-FSE-MRA). (orig.)

Digital subtraction angiography of carotid bifurcation

International Nuclear Information System (INIS)

Vries, A.R. de.

1984-01-01

This study demonstrates the reliability of digital subtraction angiography (DSA) by means of intra- and interobserver investigations as well as indicating the possibility of substituting catheterangiography by DSA in the diagnosis of carotid bifurcation. Whenever insufficient information is obtained from the combination of non-invasive investigation and DSA, a catheterangiogram will be necessary. (Auth.)

Digital subtraction angiography: myths and reality

International Nuclear Information System (INIS)

Levin, D.C.

1984-01-01

Some of the claims made about digital subtraction angiography (DSA) when it was first developed have turned out to be greatly exaggerated, and some members of the radiologic community have become disillusioned with its capabilities. The author discusses some of the limitations of DSA, and concludes that the advantages of DSA outweigh its limitations

The contribution of chemical shift imaging with digital subtracting images to the diagnosis of steatohepatitis

International Nuclear Information System (INIS)

Guo Xinghua; Wang Juanping; Zhang Chongjie; Zheng Guofang; Fan Ruiqiang; Zhu Sumei; Liu Qiwang

2006-01-01

Objective: To investigate the diagnosis value of chemical shift imaging with digital subtracting in steatohepatitis. Methods: The in-phase images were subtracted by the out-phase ones in 34 cases of steatohepatitis, and the CNR were measured on these subtracted images to estimate the steatosis of the liver. The relationship of CT grade of steatohepatitis and CNR from the subtracted images was analyzed to evaluate the relationship between CNR and the degree of hepatic steatosis. The sensitivity and specificity of the subtracting and eyeballing methods were compared with chi-square test. Results: On the subtracted images, the liver and spleen were seen nearly the same aspects as low signals, CNR=0.98±0.06, meanwhile the spongy vertebra and the subcutaneous or abdominal lipid were seen as obvious higher signals in 52 normal cases. On the 34 steatohepatitis, scattered high signals were seen in the liver, which made the signal of liver higher than that of spleen, CNR=3.25±0.91--14.35±6.10. There was positive correlation between CNR and CT grade in the 34 cases of steatohepatitis, r=0.893, P<0.01. The sensitivity and specificity of the subtracting method were 88.24% and 94. 23%, significantly higher than that of the eyeballing results, 32.35% and 80.77%, P<0.01 and P<0.05. Conclusion: Chemical shift imaging with digital subtracting is a sensitive, specific, objective method to diagnose steatohepatitis and it is of potential ability for quantitative diagnosis. (authors)

Evaluation of the minimum iodine concentration for contrast-enhanced subtraction mammography

International Nuclear Information System (INIS)

Baldelli, P; Bravin, A; Maggio, C Di; Gennaro, G; Sarnelli, A; Taibi, A; Gambaccini, M

2006-01-01

Early manifestation of breast cancer is often very subtle and is displayed in a complex and variable pattern of normal anatomy that may obscure the disease. The use of dual-energy techniques, that can remove the structural noise, and contrast media, that enhance the region surrounding the tumour, could help us to improve the detectability of the lesions. The aim of this work is to investigate the use of an iodine-based contrast medium in mammography with two different double exposure techniques: K-edge subtraction mammography and temporal subtraction mammography. Both techniques have been investigated by using an ideal source, like monochromatic beams produced at a synchrotron radiation facility and a clinical digital mammography system. A dedicated three-component phantom containing cavities filled with different iodine concentrations has been developed and used for measurements. For each technique, information about the minimum iodine concentration, which provides a significant enhancement of the detectability of the pathology by minimizing the risk due to high dose and high concentration of contrast medium, has been obtained. In particular, for cavities of 5 and 8 mm in diameter filled with iodine solutions, the minimum concentration needed to obtain a contrast-to-noise ratio of 5 with a mean glandular dose of 2 mGy has been calculated. The minimum concentrations estimated with monochromatic beams and K-edge subtraction mammography are 0.9 mg ml -1 and 1.34 mg ml -1 for the biggest and smallest details, respectively, while for temporal subtraction mammography they are 0.84 mg ml -1 and 1.31 mg ml -1 . With the conventional clinical system the minimum concentrations for the K-edge subtraction mammography are 4.13 mg ml -1 (8 mm diameter) and 5.75 mg ml -1 (5 mm diameter), while for the temporal subtraction mammography they are 1.01 mg ml -1 (8 mm diameter) and 1.57 mg ml -1 (5 mm diameter)

[The backgroud sky subtraction around [OIII] line in LAMOST QSO spectra].

Science.gov (United States)

Shi, Zhi-Xin; Comte, Georges; Luo, A-Li; Tu, Liang-Ping; Zhao, Yong-Heng; Wu, Fu-Chao

2014-11-01

At present, most sky-subtraction methods focus on the full spectrum, not the particular location, especially for the backgroud sky around [OIII] line which is very important to low redshift quasars. A new method to precisely subtract sky lines in local region is proposed in the present paper, which sloves the problem that the width of Hβ-[OIII] line is effected by the backgroud sky subtraction. The exprimental results show that, for different redshift quasars, the spectral quality has been significantly improved using our method relative to the original batch program by LAMOST. It provides a complementary solution for the small part of LAMOST spectra which are not well handled by LAMOST 2D pipeline. Meanwhile, This method has been used in searching for candidates of double-peaked Active Galactic Nuclei.

A study of transverse image reconstruction with digital subtraction angiography

International Nuclear Information System (INIS)

Sakamoto, Kiyoshi; Kotoura, Noriko; Terasawa, Yuuji; Oda, Masahiko; Gotou, Hiroshi; Nasada, Toshiya; Tanooka, Masao

1995-01-01

For digital subtraction angiography (DSA) with C-type equipment, it is possible to radiate an X-ray during rotation and to collect data at different angular settings. We tried to reconstruct transverse image from data obtained by scanning DSA images at different angular settings. 88 projection data were obtained by rotating the object at 180deg during radiation. Reconstruction was made using the convolution method with pixel value distribution for each projection. Similarly, the image quality of the reconstructed images were compared with the unsubtracted and subtracted ones. In case a part object was outside the calculating region, artifacts were generally produced. However, the artifacts were reduced by subtracting the background from the image. In addition, the cupping phenomenon caused by beam hardening was relaxed and high-quality imaging could be achieved. This method will become even more effective, if we will use it with selective angiography in which the limited area is enhanced. (author)

Subtracting and Fitting Histograms using Profile Likelihood

CERN Document Server

D'Almeida, F M L

2008-01-01

It is known that many interesting signals expected at LHC are of unknown shape and strongly contaminated by background events. These signals will be dif cult to detect during the rst years of LHC operation due to the initial low luminosity. In this work, one presents a method of subtracting histograms based on the pro le likelihood function when the background is previously estimated by Monte Carlo events and one has low statistics. Estimators for the signal in each bin of the histogram difference are calculated so as limits for the signals with 68.3% of Con dence Level in a low statistics case when one has a exponential background and a Gaussian signal. The method can also be used to t histograms when the signal shape is known. Our results show a good performance and avoid the problem of negative values when subtracting histograms.

Comparative study between rib imaging of DR dual energy subtraction technology and chest imaging

International Nuclear Information System (INIS)

Yu Jianming; Lei Ziqiao; Kong Xiangchuang

2006-01-01

Objective: To investigate the application value of DR dual energy subtraction technology in rib lesions. Methods: 200 patients were performed with chest DR dual energy subtraction, comparing the rib imaging between DR of thorax and chest imaging using ROC analysis. Results: Among the total of 200 patients, there are 50 cases of rib calcification, 7 cases of rib destruction, 22 cases of rib fracture. The calcification, destruction and fracture were displayed respectively by ribs below diaphragm and rib markings. The analytic parameter of rib imaging of DR dual energy subtraction Az is 0.9367, while that of rib imaging of chest Az is 0.6830. Conclusion: DR dual energy subtraction technology is superior to chest imaging in the displaying of rib lesion and ribs below diaphragm. (authors)

Subtraction of random coincidences in γ-ray spectroscopy: A new approach

International Nuclear Information System (INIS)

Pattabiraman, N.S.; Ghugre, S.S.; Basu, S.K.; Garg, U.; Ray, S.; Sinha, A.K.; Zhu, S.

2006-01-01

A new analytical method for estimation and subsequent subtraction of random coincidences has been developed. It utilizes the knowledge of the counts in the main diagonal of a background-subtracted symmetric data set for the estimation of the events originating from random coincidences. This procedure has been successfully applied to several data sets. It could be a valuable tool for low-fold data sets, especially for low-cross-section events

A method for subtraction of the extrarenal 'background' in dynamic 131I-hippurate renoscintigraphy

International Nuclear Information System (INIS)

Mlodkowska, E.; Liniecki, J.; Surma, M.

1979-01-01

Using a Toshiba GC-401 gamma camera with MDS computer Trinary a new method was developed for subtracting the extrarenal (extracanalicular) 'background' from the count rate recorded over the kidneys after intravenous administration of 131 I-hippurate. Mean subtraction factors of the 'blood' activity curve were calculated from a study of 27 patients who were given 51 Cr-HSA for purposes of conventional renography with 'background' subtraction. The values of the mean subtraction factors anti Fsub(R,L) for the right and left kidney, by which a blood count rate should be multiplied amounted to 0.86 +- 0.12 and 0.79 +- 0.13, respectively. A comparison of the coefficients of variation of the pure renal signal when mean vs. individually determined subtraction factors were used, and the verification of the method in unilaterally nephrectomized patients have demonstrated that determination of the factors, anti Fsub(R,L), for each patient individually is not required and sufficient precision can be obtained by using the method and factors reported in this study. (orig.) [de

Quantitative analysis of planar technetium-99m-sestamibi myocardial perfusion images using modified background subtraction

International Nuclear Information System (INIS)

Koster, K.; Wackers, F.J.; Mattera, J.A.; Fetterman, R.C.

1990-01-01

Standard interpolative background subtraction, as used for thallium-201 ( 201 Tl), may create artifacts when applied to planar technetium-99m-Sestamibi ( 99m Tc-Sestamibi) images, apparently because of the oversubtraction of relatively high extra-cardiac activity. A modified background subtraction algorithm was developed and compared to standard background subtraction in 16 patients who had both exercise-delayed 201 Tl and exercise-rest 99m Tc-Sestamibi imaging. Furthermore, a new normal data base was generated. Normal 99m Tc-Sestamibi distribution was slightly different compared to 201 Tl. Using standard background subtraction, mean defect reversibility was significantly underestimated by 99m Tc-Sestamibi compared to 201 Tl (2.8 +/- 4.9 versus -1.8 +/- 8.4, p less than 0.05). Using the modified background subtraction, mean defect reversibility on 201 Tl and 99m Tc-Sestamibi images was comparable (2.8 +/- 4.9 versus 1.7 +/- 5.2, p = NS). We conclude, that for quantification of 99m Tc-Sestamibi images a new normal data base, as well as a modification of the interpolative background subtraction method should be employed to obtain quantitative results comparable to those with 201 Tl

The digital subtraction technique in lateral urethrocystography. Die laterale Urethrozystographie in digitaler Subtraktionstechnik

Energy Technology Data Exchange (ETDEWEB)

Wolf, K. (Radiologische Abt., Caritas-Krankenhaus, Bad Mergentheim (Germany)); Peterseim, H. (Frauenklinik, Caritas-Krankenhaus, Bad Mergentheim (Germany)); Grehn, S. (Radiologische Abt., Caritas-Krankenhaus, Bad Mergentheim (Germany))

1994-09-01

The first application of the digital subtraction technique to lateral urethrocystography is described. This methodology facilitates gynecological-urological operations by providing reliable investigation results and an unambiguous image interpretation. Methods and first experiences with the digital subtraction technique in gynecological-urological diagnosis are reported. (orig.)

Spectral Subtraction Approach for Interference Reduction of MIMO Channel Wireless Systems

Directory of Open Access Journals (Sweden)

Tomohiro Ono

2005-08-01

Full Text Available In this paper, a generalized spectral subtraction approach for reducing additive impulsive noise, narrowband signals, white Gaussian noise and DS-CDMA interferences in MIMO channel DS-CDMA wireless communication systems is investigated. The interference noise reduction or suppression is essential problem in wireless mobile communication systems to improve the quality of communication. The spectrum subtraction scheme is applied to the interference noise reduction problems for noisy MIMO channel systems. The interferences in space and time domain signals can effectively be suppressed by selecting threshold values, and the computational load with the FFT is not large. Further, the fading effects of channel are compensated by spectral modification with the spectral subtraction process. In the simulations, the effectiveness of the proposed methods for the MIMO channel DS-CDMA is shown to compare with the conventional MIMO channel DS-CDMA.

[Construction of forward and reverse subtracted cDNA libraries between muscle tissue of Meishan and Landrace pigs].

Science.gov (United States)

Xu, De-Quan; Zhang, Yi-Bing; Xiong, Yuan-Zhu; Gui, Jian-Fang; Jiang, Si-Wen; Su, Yu-Hong

2003-07-01

Using suppression subtractive hybridization (SSH) technique, forward and reverse subtracted cDNA libraries were constructed between Longissimus muscles from Meishan and Landrace pigs. A housekeeping gene, G3PDH, was used to estimate the efficiency of subtractive cDNA. In two cDNA libraries, G3PDH was subtracted very efficiently at appropriate 2(10) and 2(5) folds, respectively, indicating that some differentially expressed genes were also enriched at the same folds and the two subtractive cDNA libraries were very successful. A total of 709 and 673 positive clones were isolated from forward and reverse subtracted cDNA libraries, respectively. Analysis of PCR showed that most of all plasmids in the clones contained 150-750 bp inserts. The construction of subtractive cDNA libraries between muscle tissue from different pig breeds laid solid foundations for isolating and identifying the genes determining muscle growth and meat quality, which will be important to understand the mechanism of muscle growth, determination of meat quality and practice of molecular breeding.

Intraarterial digital subtraction angiography

International Nuclear Information System (INIS)

Davis, P.C.

1987-01-01

Digital subtraction angiography (DSA) refers to a radiographic technique of amplifying low levels of contrast from intravascular iodine into an acceptable image of vascular anatomy. Initial enthusiasm suggested that DSA using intravenous injections (IV-DSA) would eliminate most conventional film-screen angiographic studies. It was soon apparent, however, that IV-DSA examinations were often compromised in those patients who most needed a less invasive study. Indeed, only a 70 to 85 percent accuracy rate was achieved with IV-DSA, primarily due to motion artifact, poor cardiac output, overlap of pertinent vessels, and inability to resolve smaller vessels

On a gauge invariant subtraction scheme for massive quantum electrodynamics

International Nuclear Information System (INIS)

Abdalla, E.; Gomes, M.; Koeberle, R.

A momentum-space subtraction scheme for massive quantum electrodynamics is proposed which respects gauge invariance, in contrast to ordinary normal product techniques. As a consequence the dependence of Green functions on the ghost mass becomes very simple and formally gauge invariant normal products of degree up to four, when subtracted according to the proposed scheme, are automatically gauge invariant. As an aplication we discuss the proof of the Adler-Bardeen theorem. Zero mass limits can be taken for Green function after the integration over intermediate states has been carried out [pt

Digital subtraction arthrography of the hips and of the shoulders

International Nuclear Information System (INIS)

Fink, B.K.; Schedel, J.; Fink, U.; Hansen, M.; Hilbertz, T.; Hagena, F.W.

1991-01-01

In a study on 60 patients, it could be shown that very good results can be achieved in the region of the shoulder joint with the use of the digital subtraction technique and of digital image intensifier radiography. A further possibility of using the digital subtraction technique for proving endoprosthesis loosenings of the hip demonstrated its importance after a short time and has become a routine method in the meantime. These two examination techniques are displayed methodologically and their clinical possibilities of use are assessed in this contribution. (orig.)

Tetracoordinate Co(II) complexes containing bathocuproine and single molecule magnetism

Czech Academy of Sciences Publication Activity Database

Smolko, L.; Černák, J.; Dušek, Michal; Titiš, J.; Boča, R.

2016-01-01

Roč. 40, č. 8 (2016), s. 6593-6598 ISSN 1144-0546 R&D Projects: GA MŠk LO1603; GA ČR(CZ) GA15-12653S EU Projects: European Commission(XE) CZ.2.16/3.1.00/24510 Institutional support: RVO:68378271 Keywords : crystal structure * single molecule magnetism * Cu(II) complexes Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 3.269, year: 2016

Radionuclide identification using subtractive clustering method

International Nuclear Information System (INIS)

Farias, Marcos Santana; Mourelle, Luiza de Macedo

2011-01-01

Radionuclide identification is crucial to planning protective measures in emergency situations. This paper presents the application of a method for a classification system of radioactive elements with a fast and efficient response. To achieve this goal is proposed the application of subtractive clustering algorithm. The proposed application can be implemented in reconfigurable hardware, a flexible medium to implement digital hardware circuits. (author)

Subtraction imaging of the ECG gated cardiac CT

Energy Technology Data Exchange (ETDEWEB)

Tanegashima, K.; Fukui, M.; Hyodo, H.

1987-05-01

The subtracting manipulation of contrast-enhanced gated cardiac CT (GCCT) images was experimentally studied with TCT 60A - 30 type (Toshiba) for clinical use, thereby reducing the amount of contrast medium (CM). Initially the optimum relationship between the concentration of CM and its injected velocity was determined using the model of resected canine hearts and in actual dogs. The emphasized good-subtracted images were obtained when the difference of CT values was approximately 40 H.U. between cardiac cavity and myocardium. Such condition was feasible in the use of 25 % Diatrizoic acid and its injected velocity of 0.02 ml/kg/sec. Finally the reduction of the amount of CM by 1/3 became possible in clinical settings. The method is applicable to multi-slice GCCT in various heart diseases.

Preliminary study of lateral cerebral angiography with reverse rotation in the digital image registration and subtraction

International Nuclear Information System (INIS)

Shen Zhenglin; Liu Dongyang; Shen Zhenghai; Li Shuping; Zhang Ziyan; Wu Yongjuan; Liu Peijun

2012-01-01

Objective: Investigate the value and feasibility of image registration with reverse rotation in lateral cerebral DSA. Methods: (1) Experimental study: the target images were subtracted directly, and subtracted again after reverse rotation. Software of registration and subtraction with reverse rotation edited by the author utilizing Visual Basic. The function of the automatic angle detection by the software were evaluated to see whether it detected the angle of line. The subtraction function of DSA by the software was evaluated. (2) Clinical retrospective study: the untreated mask and target images of 15 patients with motion along vertical axis during lateral cerebral DSA were uploaded to the software. The target images were processed with and without the software to get two sets of images. (3) Evaluation: four experienced radiologists read and compared the two sets of the images,and graded their findings. Results: (1) The automatic detection by the software suggested that the target images should be rotated counterclockwise 1.3°. The subtraction result of the software was satisfactory. (2) In the 15 sets of images, there were only three sets of images deemed optimal after traditional subtraction. After reverse rotation, artifacts were significantly reduced and the image sharper. There were ten cases with significant artifacts after traditional subtraction, and those images were sharper and showed more peripheral vessels after reverse rotation. The traditional subtraction images of two sets could not be interpreted,the reverse rotation registration images reached the diagnostic quality. (3) Subjective evaluation: there were more information and less noise and distortion in the registration images with reverse rotation than in the traditional subtraction. But the image resolution decreased slightly after reverse rotation registration. Conclusion: The registration of digital angiography with reverse rotation can improve the image quality in lateral cerebral DSA

Saving radiation dose and contrast media in intravenous digital subtraction angiography by use of bolus chasing

International Nuclear Information System (INIS)

Rueckforth, J.; Schuermann, K.; Vorwerk, D.; Guenther, R.W.

1998-01-01

Purpose: This study evaluates the dose area product, the amount of contrast media and the examination quality of the bolus chasing technique compared to the single-step technique in intravenous digital subtraction angiography. Material and Methods: 15 examinations each with bolus chasing and single-step technique were compared. The dose area product and the volume of contrast media were recorded. The examination quality was scored by two examiners. Results: With bolus chasing the volume of the administered contrast media could be decreased on average by 114 ml (43%). The difference between the dose area product of bolus chasing (722 dGy/cm 2 ) and single-step technique (1910 dGy/cm 2 ) was significant. No significant difference in examination quality was found. Conclusions: The intravenous bolus chasing technique is a practicable method. Compared to the single-step technique it allows a remarkable dose reduction and a low consumption of contrast media without restriction of examination quality. (orig.) [de

Exercise intravenous digital subtraction angiography

International Nuclear Information System (INIS)

Yiannikas, J.

1986-01-01

Attempts to use exercise ventriculography have been made, not only to give diagnostic and perhaps even prognostic information in patients with coronary artery disease, but also in patients with valvular heart disease both before and after surgical intervention. Clearly an accurate method of assessing ventricular function under conditions of stress in various cardiac diseases would provide important information that would help in patient management. Exercise ventriculography using gated blood pool equilibrium technetium studies are widely used, but are limited by spatial resolution and by the foreshortening affects of visualizing the left ventricular chamber in the left anterior oblique view. First pass radionuclide studies have the added advantage of being able to visualize the ventricular chamber in the anterior or even the right anterior oblique view, but are even more limited by their spatial resolution problems. Several investigations have shown that digital subtraction angiography produces left ventricular images with a spatial resolution almost identical to that of conventional contrast ventriculography, but without the inherent problems of cardiac arrhythmias, which often limit the assessment of left ventricular function. Because of its ability to accurately delineate wall motion abnormalities, the technique may provide an adequate assessment of global and regional left ventricular function after exercise. Digital subtraction angiography may identify ischemic wall motion abnormalities produced by exercise in patients who already had significant permanent left ventricular damage from myocardial infarction

A comparative study of additive and subtractive manufacturing for dental restorations.

Science.gov (United States)

Bae, Eun-Jeong; Jeong, Il-Do; Kim, Woong-Chul; Kim, Ji-Hwan

2017-08-01

Digital systems have recently found widespread application in the fabrication of dental restorations. For the clinical assessment of dental restorations fabricated digitally, it is necessary to evaluate their accuracy. However, studies of the accuracy of inlay restorations fabricated with additive manufacturing are lacking. The purpose of this in vitro study was to evaluate and compare the accuracy of inlay restorations fabricated by using recently introduced additive manufacturing with the accuracy of subtractive methods. The inlay (distal occlusal cavity) shape was fabricated using 3-dimensional image (reference data) software. Specimens were fabricated using 4 different methods (each n=10, total N=40), including 2 additive manufacturing methods, stereolithography apparatus and selective laser sintering; and 2 subtractive methods, wax and zirconia milling. Fabricated specimens were scanned using a dental scanner and then compared by overlapping reference data. The results were statistically analyzed using a 1-way analysis of variance (α=.05). Additionally, the surface morphology of 1 randomly (the first of each specimen) selected specimen from each group was evaluated using a digital microscope. The results of the overlap analysis of the dental restorations indicated that the root mean square (RMS) deviation observed in the restorations fabricated using the additive manufacturing methods were significantly different from those fabricated using the subtractive methods (Padditive manufacturing methods (P=.466). Similarly, no significant differences were found between wax and zirconia, the subtractive methods (P=.986). The observed RMS values were 106 μm for stereolithography apparatus, 113 μm for selective laser sintering, 116 μm for wax, and 119 μm for zirconia. Microscopic evaluation of the surface revealed a fine linear gap between the layers of restorations fabricated using stereolithography apparatus and a grooved hole with inconsistent weak scratches

Subtractions in the Adler sum rule and violation of charge symmetry

International Nuclear Information System (INIS)

Dominguez, C.A.; Moreno, H.; Zepeda, A.

1976-01-01

The consequences of a once-subtracted dispersion relation in the derivation of the Adler sum rule are investigated. It is shown that one can expect a breakdown of charge symmetry, of the isotriplet-current hypothesis, and of scaling of the structure functions. These breakdowns are related to the possible presence of a nonzero subtraction function at asymptotic energies and arbitrary q 2 . We also comment about second-class currents and PCAC (partial conservation of axial-vector current) relations

Intravenous digital subtraction angiography in the assessment of patients with left to right shunts before and after surgical correction

International Nuclear Information System (INIS)

Yiannikas, J.; Moodie, D.S.; Gill, C.C.; Sterba, R.; McIntyre, R.; Buonocore, E.

1984-01-01

Pre- and postoperative structural changes and pulmonary to systemic flow (QP/QS) ratios were assessed using digital angiography in 34 patients documented to have a left to right shunt at cardiac catheterization. There were 16 men and 18 women whose ages ranged from 4 months to 60 years. The radiographic single mask mode was used for all digital subtraction angiographic studies with a typical radiographic sequence being 80 to 100 kV, 5 to 10 mA/frame at six frames/s for 15 seconds. Renografin-76 was used as a bolus injection at 0.5 to 1.0 ml/kg via an arm vein in most patients. The level of the left to right shunt and any associated anomalies were noted and compared with results from cardiac catheterization. Digital subtraction angiographic flow curves were generated from the pulmonary arteries, and QP/QS ratios were calculated pre- and postoperatively using the gamma variate fit method and compared with the QP/QS ratio from first pass radionuclide studies. A strong correlation between preoperative digital subtraction angiographically derived QP/QS ratio and radionuclide-derived QP/QS ratio was found, with an r value equal to 0.89, p less than 0.0001. Postoperatively, all patients had a QP/QS ratio less than 1.2:1.0 for both digital subtraction angiography and radionuclide studies. The level of left to right shunt was accurately assessed in all patients, and its absence observed postoperatively. Associated anomalies, such as a persistent left superior vena cava, coarctation of the aorta and partial anomalous venous return, were identified in all cases

IMPROVED BACKGROUND SUBTRACTION FOR THE SLOAN DIGITAL SKY SURVEY IMAGES

International Nuclear Information System (INIS)

Blanton, Michael R.; Kazin, Eyal; Muna, Demitri; Weaver, Benjamin A.; Price-Whelan, Adrian

2011-01-01

We describe a procedure for background subtracting Sloan Digital Sky Survey (SDSS) imaging that improves the resulting detection and photometry of large galaxies on the sky. Within each SDSS drift scan run, we mask out detected sources and then fit a smooth function to the variation of the sky background. This procedure has been applied to all SDSS-III Data Release 8 images, and the results are available as part of that data set. We have tested the effect of our background subtraction on the photometry of large galaxies by inserting fake galaxies into the raw pixels, reanalyzing the data, and measuring them after background subtraction. Our technique results in no size-dependent bias in galaxy fluxes up to half-light radii r 50 ∼ 100 arcsec; in contrast, for galaxies of that size the standard SDSS photometric catalog underestimates fluxes by about 1.5 mag. Our results represent a substantial improvement over the standard SDSS catalog results and should form the basis of any analysis of nearby galaxies using the SDSS imaging data.

Purification, crystallization, X-ray diffraction analysis and phasing of an engineered single-chain PvuII restriction endonuclease

International Nuclear Information System (INIS)

Meramveliotaki, Chrysi; Kotsifaki, Dina; Androulaki, Maria; Hountas, Athanasios; Eliopoulos, Elias; Kokkinidis, Michael

2007-01-01

PvuII is the first type II restriction endonuclease to be converted from its wild-type homodimeric form into an enzymatically active single-chain variant. The enzyme was crystallized and phasing was successfully performed by molecular replacement. The restriction endonuclease PvuII from Proteus vulgaris has been converted from its wild-type homodimeric form into the enzymatically active single-chain variant scPvuII by tandemly joining the two subunits through the peptide linker Gly-Ser-Gly-Gly. scPvuII, which is suitable for the development of programmed restriction endonucleases for highly specific DNA cleavage, was purified and crystallized. The crystals diffract to a resolution of 2.35 Å and belong to space group P4 2 , with unit-cell parameters a = b = 101.92, c = 100.28 Å and two molecules per asymmetric unit. Phasing was successfully performed by molecular replacement

Computed tomography lung iodine contrast mapping by image registration and subtraction

Science.gov (United States)

Goatman, Keith; Plakas, Costas; Schuijf, Joanne; Beveridge, Erin; Prokop, Mathias

2014-03-01

Pulmonary embolism (PE) is a relatively common and potentially life threatening disease, affecting around 600,000 people annually in the United States alone. Prompt treatment using anticoagulants is effective and saves lives, but unnecessary treatment risks life threatening haemorrhage. The specificity of any diagnostic test for PE is therefore as important as its sensitivity. Computed tomography (CT) angiography is routinely used to diagnose PE. However, there are concerns it may over-report the condition. Additional information about the severity of an occlusion can be obtained from an iodine contrast map that represents tissue perfusion. Such maps tend to be derived from dual-energy CT acquisitions. However, they may also be calculated by subtracting pre- and post-contrast CT scans. Indeed, there are technical advantages to such a subtraction approach, including better contrast-to-noise ratio for the same radiation dose, and bone suppression. However, subtraction relies on accurate image registration. This paper presents a framework for the automatic alignment of pre- and post-contrast lung volumes prior to subtraction. The registration accuracy is evaluated for seven subjects for whom pre- and post-contrast helical CT scans were acquired using a Toshiba Aquilion ONE scanner. One hundred corresponding points were annotated on the pre- and post-contrast scans, distributed throughout the lung volume. Surface-to-surface error distances were also calculated from lung segmentations. Prior to registration the mean Euclidean landmark alignment error was 2.57mm (range 1.43-4.34 mm), and following registration the mean error was 0.54mm (range 0.44-0.64 mm). The mean surface error distance was 1.89mm before registration and 0.47mm after registration. There was a commensurate reduction in visual artefacts following registration. In conclusion, a framework for pre- and post-contrast lung registration has been developed that is sufficiently accurate for lung subtraction

Clinical utility of Gd-DTPA subtraction MR imaging for spinal bone metastasis

International Nuclear Information System (INIS)

Ando, Keiichi; Murakami, Masao; Kuroda, Yasumasa

1993-01-01

Based on reports that Gd-DTPA contributes to the detection of tumors, we used it in 31 cases (97 lesions) of spinal bone metastases. The result was that Gd-DTPA increased the intensity of tumors and the surrounding bone marrow to almost the same level in 53%. To show the metastases clearly, an existing subtraction command system was utilized. The technique included the pixel-by-pixel method, to obtain a Gd-DTPA T1-weighted image (T1WI) subtracted by the original T1WI. The detectability of the subtraction image was improved up to 96%, but was less than the original T1WI (99%). Because of the different imaging rationale between two methods, a means to assess the quality of diagnosis must be proposed. To check the normal background, the same kind of postprocessing was performed in 21 patients without malignancy. Gd-DTPA prefusion was highest in the paravertebral veins, moderate in muscles and epidural fat, and lowest in the spinal cord, intervertebral disk and bone cortex. Gd-DTPA enhanced subtraction MR imaging provides a new diagnostic tool to detect and to assess bone metastasis. (author)

Ictal technetium-99 m ethyl cysteinate dimer single-photon emission tomographic findings in epileptic patients with polymicrogyria syndromes: A subtraction of ictal-interictal SPECT coregistered to MRI study

International Nuclear Information System (INIS)

Wichert-Ana, Lauro; Mazzoncini de Azevedo-Marques, Paulo; Santos, Antonio C.; Araujo, David; Ferrari Oliveira, Lucas; Fernandes, Regina M.F.; Velasco, Tonicarlo R.; Sakamoto, Americo C.; Kato, Mery; Muxfeldt Bianchin, Marino

2008-01-01

To describe the ictal technetium-99 m-ECD SPECT findings in polymicrogyria syndromes (PMG) during epileptic seizures. We investigated 17 patients with PMG syndromes during presurgical workup, which included long-term video-electroencephalographic (EEG) monitoring, neurological and psychiatry assessments, invasive EEG, and the subtraction of ictal-interictal SPECT coregistered to magnetic resonance imaging (MRI) (SISCOM). The analysis of the PMG cortex, using SISCOM, revealed intense hyperperfusion in the polymicrogyric lesion during epileptic seizures in all patients. Interestingly, other localizing investigations showed heterogeneous findings. Twelve patients underwent epilepsy surgery, three achieved seizure-freedom, five have worthwhile improvement, and four patients remained unchanged. Our study strongly suggests the involvement of PMG in seizure generation or early propagation. Both conventional ictal single-photon emission computed tomography (SPECT) and SISCOM appeared as the single contributive exam to suggest the localization of the epileptogenic zone. Despite the limited number of resective epilepsy surgery in our study (n = 9), we found a strong prognostic role of SISCOM in predicting surgical outcome. This result may be of great value on surgical decision-making of whether or not the whole or part of the PMG lesion should be surgically resected. (orig.)

Ictal technetium-99 m ethyl cysteinate dimer single-photon emission tomographic findings in epileptic patients with polymicrogyria syndromes: A subtraction of ictal-interictal SPECT coregistered to MRI study

Energy Technology Data Exchange (ETDEWEB)

Wichert-Ana, Lauro [University of Sao Paulo, Center for Epilepsy Surgery, Department of Neurology, Psychiatry and Clinical Psychology, Ribeirao Preto (Brazil); Hospital das Clinicas, USP, Centro de Cirurgia de Epilepsia, CIREP, Ribeirao Preto, SP (Brazil); Mazzoncini de Azevedo-Marques, Paulo; Santos, Antonio C.; Araujo, David [University of Sao Paulo, Center for Imaging Science and Medical Physics, Department of Internal Medicine, Ribeirao Preto (Brazil); Ferrari Oliveira, Lucas [Federal University of Pelotas, Informatics Department, Pelotas, RS (Brazil); Fernandes, Regina M.F.; Velasco, Tonicarlo R.; Sakamoto, Americo C. [University of Sao Paulo, Center for Epilepsy Surgery, Department of Neurology, Psychiatry and Clinical Psychology, Ribeirao Preto (Brazil); Kato, Mery [University of Sao Paulo, Division of Nuclear Medicine, Department of Internal Medicine from the Ribeirao Preto Medical School, Ribeirao Preto (Brazil); Muxfeldt Bianchin, Marino [Rio Grande do Sul Federal University, Neurology Division, HCPA, Porto Alegre, RS (Brazil)

2008-06-15

To describe the ictal technetium-99 m-ECD SPECT findings in polymicrogyria syndromes (PMG) during epileptic seizures. We investigated 17 patients with PMG syndromes during presurgical workup, which included long-term video-electroencephalographic (EEG) monitoring, neurological and psychiatry assessments, invasive EEG, and the subtraction of ictal-interictal SPECT coregistered to magnetic resonance imaging (MRI) (SISCOM). The analysis of the PMG cortex, using SISCOM, revealed intense hyperperfusion in the polymicrogyric lesion during epileptic seizures in all patients. Interestingly, other localizing investigations showed heterogeneous findings. Twelve patients underwent epilepsy surgery, three achieved seizure-freedom, five have worthwhile improvement, and four patients remained unchanged. Our study strongly suggests the involvement of PMG in seizure generation or early propagation. Both conventional ictal single-photon emission computed tomography (SPECT) and SISCOM appeared as the single contributive exam to suggest the localization of the epileptogenic zone. Despite the limited number of resective epilepsy surgery in our study (n = 9), we found a strong prognostic role of SISCOM in predicting surgical outcome. This result may be of great value on surgical decision-making of whether or not the whole or part of the PMG lesion should be surgically resected. (orig.)

Tomosynthesis applied to digital subtraction angiography

International Nuclear Information System (INIS)

Kruger, R.A.; Sedaghati, M.; Roy, D.G.; Liu, P.; Nelson, J.A.; Kubal, W.; Del Rio, P.

1984-01-01

This extension of the author's previous work on tomographic digital subtraction angiography (DSA) describes the theory of tomosynthetic DSA image reconstruction techniques. In addition to developing the resolution limits resulting from x-ray exposure length and image intensifier field curvature, the authors describe one method of image formation and show tomosynthetic DSA images of animal and human anatomy. Methods for improving the present technique are discussed

Digital subtraction angiography

International Nuclear Information System (INIS)

Neuwirth, J. Jr.; Bohutova, J.

1987-01-01

The quality of radiodiagnostic methods to a great extent depends on the quality of the resulting image. The basic technical principles are summed up of the different parts of digital subtraction angiography apparatus and of methods of improving the image. The instrument is based on a videochain consisting of an X-ray tube, an intensifier of the radiographic image, optical parts, a video camera, an analog-to-digital converter and a computer. The main advantage of the digitally processed image is the possibility of optimizing the image into a form which will contain the biggest amount of diagnostically valuable information. Described are the mathematical operations for improving the digital image: spatial filtration, pixel shift, time filtration, image integration, time interval differentation and matched filtering. (M.D.). 8 refs., 3 figs

Preoperative radiological diagnosis by 99mTc·MIBI-99mTc subtraction scintigraphy for primary hyperparathyroidism

International Nuclear Information System (INIS)

Inouye, Takahiro; Tomita, Toshiki; Shinden, Seiichi; Takagi, Hitoshi; Kano, Shigeru.

1996-01-01

Preoperative radiological diagnosis constitutes the most important factor for the surgical treatment of hyperparathyroidism. In this regard, MRI is useful for detecting the abnormal parathyroid, but it is often difficult to localize it using MRI only. It is thus necessary to combine this procedure with excellent subtraction scintigraphy. We performed both 201 Tl- 99m Tc and 99m Tc·MIBI- 99m Tc subtraction scintigraphy in seven patients with primary hyperparathyroidism and compared them the radiological results. Five patients presented parathyroid adenomas and the rest hypertrophy of the parathyroid. We could detect the abnormal parathyroid in four patients (57.1%) by 201 Tl- 99m Tc subtraction scintigraphy and in six patients (85.7%) by 99m Tc·MIBI- 99m Tc subtraction scintigraphy. We therefore believe that 99m Tc·MIBI- 99m Tc subtraction scintigraphy will become an essential examination for primary hyperparathyroidism rather than the presently employed 201 Tl- 99m Tc subtraction scintigraphy. (author)

Parathyroid localizlation by 201Tl-99mTc subtraction scintigraphy

International Nuclear Information System (INIS)

Rademaker, P.; Meijer, S.; Piers, D.A.

1990-01-01

Subtraction scintigraphy with 201 Tl and 99m Tc for parathyroid localization was performed preoperatively in 13 patients with chronic renal failure and secondary hyperparathyroidism. Twenty of the 37 examined pathological glands were predicted correctly (sensitivity 54%). In 3 patients with recurrent hyperparathyroidism after surgery all pathological glands found at second operation had been detected correctly by subtraction scintigraphy. We conclude that this localization method has a limited value when used prior to first neck exploration in secondary hyperparathyroidism. In persistent hyperparathyroidism after surgery it may play a useful role in localizing missed and ectopic glands. (author)

A comparison between magnetic resonance angiography at 3 teslas (time-of-flight and contrast-enhanced and flat-panel digital subtraction angiography in the assessment of embolized brain aneurysms

Directory of Open Access Journals (Sweden)

Guilherme S. Nakiri

2011-01-01

Full Text Available PURPOSE: To compare the time-of-flight and contrast-enhanced- magnetic resonance angiography techniques in a 3 Tesla magnetic resonance unit with digital subtraction angiography with the latest flat-panel technology and 3D reconstruction in the evaluation of embolized cerebral aneurysms. INTRODUCTION: Many embolized aneurysms are subject to a recurrence of intra-aneurismal filling. Traditionally, imaging surveillance of coiled aneurysms has consisted of repeated digital subtraction angiography. However, this method has a small but significant risk of neurological complications, and many authors have advocated the use of noninvasive imaging methods for the surveillance of embolized aneurysms. METHODS: Forty-three aneurysms in 30 patients were studied consecutively between November 2009 and May 2010. Two interventional neuroradiologists rated the time-of-flight-magnetic resonance angiography, the contrast-enhanced-magnetic resonance angiography, and finally the digital subtraction angiography, first independently and then in consensus. The status of aneurysm occlusion was assessed according to the Raymond scale, which indicates the level of recanalization according to degrees: Class 1: excluded aneurysm; Class 2: persistence of a residual neck; Class 3: persistence of a residual aneurysm. The agreement among the analyses was assessed by applying the Kappa statistic. RESULTS: Inter-observer agreement was excellent for both methods (K = 0.93; 95 % CI: 0.84-1. Inter-technical agreement was almost perfect between time-of-flight-magnetic resonance angiography and digital subtraction angiography (K = 0.98; 95 % CI: 0.93-1 and between time-of-flight-magnetic resonance angiography and contrast-enhanced-magnetic resonance angiography (K = 0.98; 95% CI: 0.93-1. Disagreement occurred in only one case (2.3%, which was classified as Class I by time-of-flight-magnetic resonance angiography and Class II by digital subtraction angiography. The agreement between

Performance of a video-image-subtraction-based patient positioning system

International Nuclear Information System (INIS)

Milliken, Barrett D.; Rubin, Steven J.; Hamilton, Russell J.; Johnson, L. Scott; Chen, George T.Y.

1997-01-01

Purpose: We have developed and tested an interactive video system that utilizes image subtraction techniques to enable high precision patient repositioning using surface features. We report quantitative measurements of system performance characteristics. Methods and Materials: Video images can provide a high precision, low cost measure of patient position. Image subtraction techniques enable one to incorporate detailed information contained in the image of a carefully verified reference position into real-time images. We have developed a system using video cameras providing orthogonal images of the treatment setup. The images are acquired, processed and viewed using an inexpensive frame grabber and a PC. The subtraction images provide the interactive guidance needed to quickly and accurately place a patient in the same position for each treatment session. We describe the design and implementation of our system, and its quantitative performance, using images both to measure changes in position, and to achieve accurate setup reproducibility. Results: Under clinical conditions (60 cm field of view, 3.6 m object distance), the position of static, high contrast objects could be measured with a resolution of 0.04 mm (rms) in each of two dimensions. The two-dimensional position could be reproduced using the real-time image display with a resolution of 0.15 mm (rms). Two-dimensional measurement resolution of the head of a patient undergoing treatment for head and neck cancer was 0.1 mm (rms), using a lateral view, measuring the variation in position of the nose and the ear over the course of a single radiation treatment. Three-dimensional repositioning accuracy of the head of a healthy volunteer using orthogonal camera views was less than 0.7 mm (systematic error) with an rms variation of 1.2 mm. Setup adjustments based on the video images were typically performed within a few minutes. The higher precision achieved using the system to measure objects than to reposition

Preparation of a differentially expressed, full-length cDNA expression library by RecA-mediated triple-strand formation with subtractively enriched cDNA fragments

NARCIS (Netherlands)

Hakvoort, T. B.; Spijkers, J. A.; Vermeulen, J. L.; Lamers, W. H.

1996-01-01

We have developed a fast and general method to obtain an enriched, full-length cDNA expression library with subtractively enriched cDNA fragments. The procedure relies on RecA-mediated triple-helix formation of single-stranded cDNA fragments with a double-stranded cDNA plasmid library. The complexes

Aortic blood flow subtraction: an alternative method for measuring total renal blood flow in conscious dogs

DEFF Research Database (Denmark)

Sandgaard, N C F; Andersen, J L; Holstein-Rathlou, N-H

2002-01-01

We have measured total renal blood flow (TRBF) as the difference between signals from ultrasound flow probes implanted around the aorta above and below the renal arteries. The repeatability of the method was investigated by repeated, continuous infusions of angiotensin II and endothelin-1 seven...... arterial blood pressure by 49% and decreased TRBF by 12%, providing an increase in renal vascular resistance of 69%. Dynamic analysis showed autoregulation of renal blood flow in the frequency range ... of TRBF by aortic blood flow subtraction is a practical and reliable method that allows direct comparison of excretory function and renal blood flow from two kidneys. The method also allows direct comparison between TRBF and flow in the caudal aorta....

Development of a Single Detector Ring Micro Crystal Element Scanner: QuickPET II

Directory of Open Access Journals (Sweden)

Robert S. Miyaoka

2005-04-01

Full Text Available This article describes a single ring version of the micro crystal element scanner (MiCES and investigation of its spatial resolution imaging characteristics for mouse positron emission tomography (PET imaging. This single ring version of the MiCES system, referred to as QuickPET II, consists of 18 MiCE detector modules mounted as a single ring in a vertical gantry. The system has a 5.76-cm transverse field of view and a 1.98-cm axial field of view. In addition to the scanner and data acquisition system, we have developed an iterative reconstruction that includes a model of the system's detector response function. Evaluation images of line sources and mice have been acquired. Using filtered backprojection, the resolution for a reconstructed line source has been measured at 1.2 mm full width at half maximum. F-18-2-fluoro-2-deoxyglucose mouse PET images are provided. The result shows that QuickPET II has the imaging characteristics to support high-resolution, static mouse PET studies using 18-F labeled compounds.

Addition and Subtraction but Not Multiplication and Division Cause Shifts of Spatial Attention

Directory of Open Access Journals (Sweden)

Mengjin Li

2018-05-01

Full Text Available Many studies have shown that solving addition and subtraction problems can induce overt shifts of spatial attention. In particular, right-side targets are detected faster than left-side targets when preceded by an addition operation, while left-side targets are detected faster than right-side targets when preceded by a subtraction operation. However, the interaction between space and arithmetic in multiplication or division is hardly studied and remains controversial. In order to make a strong case for the interaction between space and mental arithmetic, we attempted to replicate the spatial-arithmetic association in addition and subtraction (Experiment 1, and at the same time investigated whether shift of spatial attention would also be induced by multiplication or division operations (Experiment 2. We found that solving addition problems facilitated the detection of right-side targets, whereas left-side targets were detected faster after solving subtraction problems. However, no interaction between space and arithmetic operation was observed in multiplication or division. The implication of these findings is discussed.

Novel Ratio Subtraction and Isoabsorptive Point Methods for ...

African Journals Online (AJOL)

Purpose: To develop and validate two innovative spectrophotometric methods used for the simultaneous determination of ambroxol hydrochloride and doxycycline in their binary mixture. Methods: Ratio subtraction and isoabsorptive point methods were used for the simultaneous determination of ambroxol hydrochloride ...

Search for Electroweak Single-Top Quark Production with the CDF II Experiment

Energy Technology Data Exchange (ETDEWEB)

Buehler, Matthias; /Karlsruhe U., EKP

2006-08-01

The CDF II experiment and the Tevatron proton-antiproton collider are parts of the Fermi National Laboratories (Fermilab). The Fermilab is located in the vicinity of Chicago, USA. Today, the Tevatron is the only collider which is able to produce the heaviest known elementary particle, the top quark. The top quark was discovered at the Tevatron by the CDF and the D0 collaborations in 1995 [1]. So far, all the top quarks found are produced via the strong interaction as top-antitop pairs. The Standard Model of elementary particle physics also predicts single-top quark production via the electroweak interaction. This production mode has not yet been observed. The CDF and the D0 collaborations have set upper limits on the cross section for that process in Run I [2, 3] and improved those results in Run II [4, 5]. Single-top quark production is one of the major interests in Run II of the Tevatron as it offers several ways to test the Standard Model and to search for potential physics beyond the Standard Model. The measurement of the cross section of singly produced top quarks via the electroweak interaction offers the possibility to determine the Cabbibo-Kobayashi-Maskawa (CKM) matrix element V{sub tb} directly. The CKM matrix defines the transformation from the eigenstates of the electroweak interactions to the mass eigenstates of the quarks. V{sub tb} gives the strength of the coupling at the Wtb vertex. The single-top quark is produced at this vertex and therefore the cross section of the single-top quark production is directly proportional to |V{sub tb}|{sup 2}. In the Standard Model, three generations of quarks and the unitarity of the CKM matrix are predicted. This leads to V{sub tb} {approx} 1. Up to now, there is no possibility to measure V{sub tb} without using the assumption that there are a certain number of quark generations. Since the measurement of the cross section of single-top quark production is independent of this assumption it could verify another

A simultaneous all-optical half/full-subtraction strategy using cascaded highly nonlinear fibers

Science.gov (United States)

Singh, Karamdeep; Kaur, Gurmeet; Singh, Maninder Lal

2018-02-01

Using non-linear effects such as cross-gain modulation (XGM) and cross-phase modulation (XPM) inside two highly non-linear fibres (HNLF) arranged in cascaded configuration, a simultaneous half/full-subtracter is proposed. The proposed simultaneous half/full-subtracter design is attractive due to several features such as input data pattern independence and usage of minimal number of non-linear elements i.e. HNLFs. Proof of concept simulations have been conducted at 100 Gbps rate, indicating fine performance, as extinction ratio (dB) > 6.28 dB and eye opening factors (EO) > 77.1072% are recorded for each implemented output. The proposed simultaneous half/full-subtracter can be used as a key component in all-optical information processing circuits.

The development of MOSA-II multichannel optical spectrum analyzer

International Nuclear Information System (INIS)

Guo Li; Yang Zhoujing; Fang Shuyao

1989-01-01

The MOSA-II Multichannel Optical Spectrum Analyzer is a high-perfor mance, easy-to-use measurment system for extremely rapid spectral data acquistion, processing and presentation. It consists of four parts: vidicon, data acquiring and timing circuit, the correcting circuit for the geometric distortion and the non-uniform distortion of the vidicon, IBMPC/XT and color plotter. The system has the following functions: single spectrum acquisition, continuous acquisition of multi-spectra, noise reduction, math, operations (including addition, subtraction, multiplication, and division) and geometric transform action of the spectra, and 3D-presentation of the spectra on both the color screen and the plotter. The absolute sensitivity of the system is 18 Photons/sec · mm 2 . The access time for data acquisition is 64 μs/per channel and the spectrum range is 1800 A - 8000A, the geometric distortion<2%, the amplitude error<5%

Background dose subtraction in personnel dosimetry

International Nuclear Information System (INIS)

Picazo, T.; Llorca, N.; Alabau, J.

1997-01-01

In this paper it is proposed to consider the mode of the frequency distribution of the low dose dosemeters from each clinic that uses X rays as the background environmental dose that should be subtracted from the personnel dosimetry to evaluate the doses due to practice. The problems and advantages of this indirect method to estimate the environmental background dose are discussed. The results for 60 towns are presented. (author)

Digital subtraction angiography in the assessment of cardiovascular disease

International Nuclear Information System (INIS)

Harrington, D.P.; Boxt, L.M.

1985-01-01

Digital subtraction angiography (DSA) is a new radiographic method for evaluating the cardiovascular system. It represents another in a continuing series of computer-assisted diagnostic imaging modalities. The advantages of this technique are its relatively noninvasive nature combined with diagnostically acceptable angiographic images of a variety of cardiovascular structures. Major clinical applications of DSA include its use in imaging of localized regions of peripheral arterial disease and as a screening procedure in evaluating extracranial carotid and vertebral artery disease and renovascular hypertension. Cardiac applications of DSA include assessment of ventricular function, recognition and quantification of intracardiac shunts, visualization of coronary artery bypass grafts, and the study of complex congenital cardiac malformations. Digital subtraction angiography may also be used to evaluate intracranial aneurysms and vascular tumors

Spinal pedicle subtraction osteotomy for fixed sagittal imbalance patients

Science.gov (United States)

Hyun, Seung-Jae; Kim, Yongjung J; Rhim, Seung-Chul

2013-01-01

In addressing spinal sagittal imbalance through a posterior approach, the surgeon now may choose from among a variety of osteotomy techniques. Posterior column osteotomies such as the facetectomy or Ponte or Smith-Petersen osteotomy provide the least correction, but can be used at multiple levels with minimal blood loss and a lower operative risk. Pedicle subtraction osteotomies provide nearly 3 times the per-level correction of Ponte/Smith-Petersen osteotomies; however, they carry increased technical demands, longer operative time, and greater blood loss and associated significant morbidity, including neurological injury. The literature focusing on pedicle subtraction osteotomy for fixed sagittal imbalance patients is reviewed. The long-term overall outcomes, surgical tips to reduce the complications and suggestions for their proper application are also provided. PMID:24340276

Introduction to the principles of Digital Subtraction Angiography (DSA)

Energy Technology Data Exchange (ETDEWEB)

Kaplanis, P [Medical Physics Department, Nicosia General Hospital, Nicosia (Cyprus)

1998-12-31

Medical applications of advanced technology have rapidly become more sophisticated and more widespread. The field of diagnostic imaging is by no means an exception. There has been a number of breathtaking developments in the field of medical imaging in recent years. Today higher quality, greater clarity and more minute precision are considered not advantages but necessities. Hence new developments are concentrated in the data acquisition and image processing based on the microprocessor controlled modules interfaced with state of the art radiological imaging equipment. One such development is the subtraction of x-rays vis a computer for better visualization of blood vessels, cavities of the heart and of the coronary and pulmonary vascular system. This procedure is termed Digital Subtraction Angiography (DSA). (author). 5 refs, 3 figs.

Introduction to the principles of Digital Subtraction Angiography (DSA)

International Nuclear Information System (INIS)

Kaplanis, P.

1997-01-01

Medical applications of advanced technology have rapidly become more sophisticated and more widespread. The field of diagnostic imaging is by no means an exception. There has been a number of breathtaking developments in the field of medical imaging in recent years. Today higher quality, greater clarity and more minute precision are considered not advantages but necessities. Hence new developments are concentrated in the data acquisition and image processing based on the microprocessor controlled modules interfaced with state of the art radiological imaging equipment. One such development is the subtraction of x-rays vis a computer for better visualization of blood vessels, cavities of the heart and of the coronary and pulmonary vascular system. This procedure is termed Digital Subtraction Angiography (DSA). (author)

Four-State Continuous-Variable Quantum Key Distribution with Photon Subtraction

Science.gov (United States)

Li, Fei; Wang, Yijun; Liao, Qin; Guo, Ying

2018-06-01

Four-state continuous-variable quantum key distribution (CVQKD) is one of the discretely modulated CVQKD which generates four nonorthogonal coherent states and exploits the sign of the measured quadrature of each state to encode information rather than uses the quadrature \\hat {x} or \\hat {p} itself. It has been proven that four-state CVQKD is more suitable than Gaussian modulated CVQKD in terms of transmission distance. In this paper, we propose an improved four-state CVQKD using an non-Gaussian operation, photon subtraction. A suitable photon-subtraction operation can be exploited to improve the maximal transmission of CVQKD in point-to-point quantum communication since it provides a method to enhance the performance of entanglement-based (EB) CVQKD. Photon subtraction not only can lengthen the maximal transmission distance by increasing the signal-to-noise rate but also can be easily implemented with existing technologies. Security analysis shows that the proposed scheme can lengthen the maximum transmission distance. Furthermore, by taking finite-size effect into account we obtain a tighter bound of the secure distance, which is more practical than that obtained in the asymptotic limit.

A subtraction scheme for computing QCD jet cross sections at NNLO: integrating the doubly unresolved subtraction terms

CERN Document Server

Somogyi, Gabor

2013-01-01

We finish the definition of a subtraction scheme for computing NNLO corrections to QCD jet cross sections. In particular, we perform the integration of the soft-type contributions to the doubly unresolved counterterms via the method of Mellin-Barnes representations. With these final ingredients in place, the definition of the scheme is complete and the computation of the regularised doubly virtual contribution to the NNLO cross section becomes feasible.

Misconception on Addition and Subtraction of Fraction at Primary School Students in Fifth-Grade

Science.gov (United States)

Trivena, V.; Ningsih, A. R.; Jupri, A.

2017-09-01

This study aims to investigate the mastery concept of the student in mathematics learning especially in addition and subtraction of fraction at primary school level. By using qualitative research method, the data were collected from 23 grade five students (10-11-year-old). Instruments included a test, that is accompanied by Certainty Response Index (CRI) and interview with students and teacher. The result of the test has been obtained, then processed by analyzing the student’s answers for each item and then grouped by the CRI categories that combined with the results of the interview with students and teacher. The results showed that student’s mastery-concept on additional and subtraction dominated by category ‘misconception’. So, we can say that mastery-concept on addition and subtraction of fraction at fifth-grade students is still low. Finally, the impact can make most of primary student think that learning addition and subtraction of fraction in mathematics is difficult.

A High Energy and High Efficiency Spectral Shaping Single Frequency Fiber Laser, Phase II

Data.gov (United States)

National Aeronautics and Space Administration — This SBIR phase II project proposes a single frequency high energy fiber laser system for coherent Lidar systems for remote sensing. Current state-of-art...

Venous digital subtraction angiography for diagnosis of renal artery stenosis in arterial hypertony

International Nuclear Information System (INIS)

Schoerner, W.; Kempter, H.; Banzer, D.; Aviles, C.; Weiss, T.; Felix, R.

1984-01-01

Venous digital subtraction angiography was performed in 248 patients for the diagnosis of renal arterial stenosis. In 88% of the investigations the stenosis could be found. Comparison of digital angiography and conventional angiography was made for 57 renal arteries (25 investigations). In 52 renal arteries we found the same results with both methods, in 5 renal arteries we found the same results with both methods, in 5 renal arteries the digital angiography showed false positive results. The spatial resolution of digital subtraction angiography is sufficient for the correct diagnosis of significant renal arterial stenosis. With regard to the lower invasion of digital subtraction angiography compared to conventional angiography the first method should be used for clarification of renal arterial hypertension. (orig.)

Syntheses, structures, and properties of imidazolate-bridged Cu(II)-Cu(II) and Cu(II)-Zn(II) dinuclear complexes of a single macrocyclic ligand with two hydroxyethyl pendants.

Science.gov (United States)

Li, Dongfeng; Li, Shuan; Yang, Dexi; Yu, Jiuhong; Huang, Jin; Li, Yizhi; Tang, Wenxia

2003-09-22

The imidazolate-bridged homodinuclear Cu(II)-Cu(II) complex, [(CuimCu)L]ClO(4).0.5H(2)O (1), and heterodinuclear Cu(II)-Zn(II) complex, [(CuimZnL(-)(2H))(CuimZnL(-)(H))](ClO(4))(3) (2), of a single macrocyclic ligand with two hydroxyethyl pendants, L (L = 3,6,9,16,19,22-hexaaza-6,19-bis(2-hydroxyethyl)tricyclo[22,2,2,2(11,14)]triaconta-1,11,13,24,27,29-hexaene), have been synthesized as possible models for copper-zinc superoxide dismutase (Cu(2),Zn(2)-SOD). Their crystal structures analyzed by X-ray diffraction methods have shown that the structures of the two complexes are markedly different. Complex 1 crystallizes in the orthorhombic system, containing an imidazolate-bridged dicopper(II) [Cu-im-Cu](3+) core, in which the two copper(II) ions are pentacoordinated by virtue of an N4O environment with a Cu.Cu distance of 5.999(2) A, adopting the geometry of distorted trigonal bipyramid and tetragonal pyramid, respectively. Complex 2 crystallizes in the triclinic system, containing two similar Cu-im-Zn cores in the asymmetric unit, in which both the Cu(II) and Zn(II) ions are pentacoordinated in a distorted trigonal bipyramid geometry, with the Cu.Zn distance of 5.950(1)/5.939(1) A, respectively. Interestingly, the macrocyclic ligand with two arms possesses a chairlike (anti) conformation in complex 1, but a boatlike (syn) conformation in complex 2. Magnetic measurements and ESR spectroscopy of complex 1 have revealed the presence of an antiferromagnetic exchange interaction between the two Cu(II) ions. The ESR spectrum of the Cu(II)-Zn(II) heterodinuclear complex 2 displayed a typical signal for mononuclear trigonal bipyramidal Cu(II) complexes. From pH-dependent ESR and electronic spectroscopic studies, the imidazolate bridges in the two complexes have been found to be stable over broad pH ranges. The cyclic voltammograms of the two complexes have been investigated. Both of the two complexes can catalyze the dismutation of superoxide and show rather high activity.

Accessing the diffracted wavefield by coherent subtraction

Science.gov (United States)

Schwarz, Benjamin; Gajewski, Dirk

2017-10-01

Diffractions have unique properties which are still rarely exploited in common practice. Aside from containing subwavelength information on the scattering geometry or indicating small-scale structural complexity, they provide superior illumination compared to reflections. While diffraction occurs arguably on all scales and in most realistic media, the respective signatures typically have low amplitudes and are likely to be masked by more prominent wavefield components. It has been widely observed that automated stacking acts as a directional filter favouring the most coherent arrivals. In contrast to other works, which commonly aim at steering the summation operator towards fainter contributions, we utilize this directional selection to coherently approximate the most dominant arrivals and subtract them from the data. Supported by additional filter functions which can be derived from wave front attributes gained during the stacking procedure, this strategy allows for a fully data-driven recovery of faint diffractions and makes them accessible for further processing. A complex single-channel field data example recorded in the Aegean sea near Santorini illustrates that the diffracted background wavefield is surprisingly rich and despite the absence of a high channel count can still be detected and characterized, suggesting a variety of applications in industry and academia.

Digital Subtraction Angiography (DSA) "Road Map": An Angiographic Tool

Science.gov (United States)

Turski, P. A.; Stieghorst, M. F.; Strother, C. M.; Crummy, A. B.; Lieberman, R. P.; Mistretta, C. A.

1982-12-01

Continuous Digital subtraction combined with intraarterial injections of contrast medium permits the display of arterial structures during real time fluoroscopy. This DSA "road map" facilitates selective catheterization and has proved useful in interventional procedures.

Comparison of two interpolative background subtraction methods using phantom and clinical data

International Nuclear Information System (INIS)

Houston, A.S.; Sampson, W.F.D.

1989-01-01

Two interpolative background subtraction methods used in scintigraphy are tested using both phantom and clinical data. Cauchy integral subtraction was found to be relatively free of artefacts but required more computing time than bilinear interpolation. Both methods may be used with reasonable confidence for the quantification of relative measurements such as left ventricular ejection fraction and myocardial perfusion index but should be avoided if at all possible in the quantification of absolute measurements such as glomerular filtration rate. (author)

Clinical application of subtraction CT imaging for evaluation of pulmonary vascular permeability

International Nuclear Information System (INIS)

Kato, Shiro; Asai, Toshihiko; Yatagai, Shigeo; Oonuma, Noboru; Ohno, Kunihiko; Nakamoto, Takaaki; Iizuka, Masahiko

1991-01-01

In this clinical study, one normal subject, one patient with primary interstitial pneumonia, one patient with segmental pneumonia due to Staphylococcus aureus, one patient with post-operative esophageal carcinoma, and two patients with mitral stenosis were studied. Dynamic CT scan images under continuous injection of low osmotic contrast medium were analyzed in series, in an attempt to evaluate vascular permeability quantitatively. The following results were obtained. Subtraction CT scan image 10 minutes after the start of contrast medium injection in two patients with pneumonia, showed a reduction of pulmonary vascular permeability following therapy. Subtraction CT scan image of the patient with post-operative esophageal carcinoma treated with 25 Gy radiation showed a discrepancy between pulmonary vascular permeability and other findings. In hemodynamically stable patients with mitral stenosis, subtraction CT images demonstrated that pulmonary vascular permeability was not affected by pulmonary congestion, irrespective of its severity. (author)

A subtraction scheme for computing QCD jet cross sections at NNLO: integrating the doubly unresolved subtraction terms

Science.gov (United States)

Somogyi, Gábor

2013-04-01

We finish the definition of a subtraction scheme for computing NNLO corrections to QCD jet cross sections. In particular, we perform the integration of the soft-type contributions to the doubly unresolved counterterms via the method of Mellin-Barnes representations. With these final ingredients in place, the definition of the scheme is complete and the computation of fully differential rates for electron-positron annihilation into two and three jets at NNLO accuracy becomes feasible.

A subtraction scheme for computing QCD jet cross sections at NNLO: integrating the doubly unresolved subtraction terms

OpenAIRE

Somogyi, Gabor

2013-01-01

We finish the definition of a subtraction scheme for computing NNLO corrections to QCD jet cross sections. In particular, we perform the integration of the soft-type contributions to the doubly unresolved counterterms via the method of Mellin-Barnes representations. With these final ingredients in place, the definition of the scheme is complete and the computation of fully differential rates for electron-positron annihilation into two and three jets at NNLO accuracy becomes feasible.

Improvement in visibility of simulated lung nodules on computed radiography (CR) chest images by use of temporal subtraction technique

International Nuclear Information System (INIS)

Oda, Nobuhiro; Fujimoto, Keiji; Murakami, Seiichi; Katsuragawa, Shigehiko; Doi, Kunio; Nakata, Hajime

1999-01-01

A temporal subtraction image obtained by subtraction of a previous image from a current one can enhance interval change on chest images. In this study, we compared the visibility of simulated lung nodules on CR images with and without temporal subtraction. Chest phantom images without and with simulated nodules were obtained as previous and current images, respectively, by a CR system. Then, subtraction images were produced with an iterative image warping technique. Twelve simulated nodules were attached on various locations of the chest phantom. The diameter of nodules having a CT number of 47 ranged from 3 mm to 10 mm. Seven radiologists subjectively evaluated the visibility of simulated nodules on CR images with and without temporal subtraction using a three-point rating scale (0: invisible, +1: questionable, +2:visible). The minimum diameter of simulated nodules visible at a frequency greater than 50% was 4 mm on the CR images with temporal subtraction and 6 mm on those without. Our results indicated that the subtraction images clearly improved the visibility of simulated nodules. (author)

Pediatric head and neck lesions: assessment of vascularity by MR digital subtraction angiography.

Science.gov (United States)

Chooi, Weng Kong; Woodhouse, Neil; Coley, Stuart C; Griffiths, Paul D

2004-08-01

Pediatric head and neck lesions can be difficult to characterize on clinical grounds alone. We investigated the use of dynamic MR digital subtraction angiography as a noninvasive adjunct for the assessment of the vascularity of these abnormalities. Twelve patients (age range, 2 days to 16 years) with known or suspected vascular abnormalities were studied. Routine MR imaging, time-of-flight MR angiography, and MR digital subtraction angiography were performed in all patients. The dynamic sequence was acquired in two planes at one frame per second by using a thick section (6-10 cm) selective radio-frequency spoiled fast gradient-echo sequence and an IV administered bolus of contrast material. The images were subtracted from a preliminary mask sequence and viewed as a video-inverted cine loop. In all cases, MR digital subtraction angiography was successfully performed. The technique showed the following: 1) slow flow lesions (two choroidal angiomas, eyelid hemangioma, and scalp venous malformation); 2) high flow lesions that were not always suspected by clinical examination alone (parotid hemangioma, scalp, occipital, and eyelid arteriovenous malformations plus a palatal teratoma); 3) a hypovascular tumor for which a biopsy could be safely performed (Burkitt lymphoma); and 4) a hypervascular tumor of the palate (cystic teratoma). Our early experience suggests that MR digital subtraction angiography can be reliably performed in children of all ages without complication. The technique provided a noninvasive assessment of the vascularity of each lesion that could not always have been predicted on the basis of clinical examination or routine MR imaging alone.

Observation of Electroweak Single Top-Quark Production with the CDF II Experiment

International Nuclear Information System (INIS)

Lueck, Jan

2009-01-01

The standard model of elementary particle physics (SM) predicts, besides the top-quark pair production via the strong interaction, also the electroweak production of single top-quarks (19). Up to now, the Fermilab Tevatron proton-antiproton-collider is the only place to produce and study top quarks emerging from hadron-hadron-collisions. Top quarks were directly observed in 1995 during the Tevatron Run I at a center-of-mass energy of √s = 1.8 TeV simultaneously by the CDF and D0 Collaborations via the strong production of top-quark pairs. Run II of the Tevatron data taking period started 2001 at √s = 1.96 TeV after a five year upgrade of the Tevatron accelerator complex and of both experiments. One main component of its physics program is the determination of the properties of the top quark including its electroweak production. Even though Run II is still ongoing, the study of the top quark is already a successful endeavor, confirmed by dozens of publications from both Tevatron experiments. A comprehensive review of top-quark physics can be found in reference. The reasons for searching for single top-quark production are compelling. As the electroweak top-quark production proceeds via a Wtb vertex, it provides the unique opportunity of the direct measurement of the CKM matrix element |V tb |, which is expected to be |V tb | ∼ 1 in the SM. Significant deviations from unity could be an indication of a fourth quark generation, a production mode via flavor-changing neutral currents, and other new phenomena, respectively. There are two dominating electroweak top-quark production modes at the Fermilab Tevatron: the t-channel exchange of a virtual W boson striking a b quark and the s-channel production of a timelike W boson via the fusion of two quarks. In proton-antiproton-collisions the third electroweak production mode, the associated Wt production of an on-shell W boson in conjunction with a top quark has a comparatively negligible small predicted cross section

Observation of Electroweak Single Top-Quark Production with the CDF II Experiment

Energy Technology Data Exchange (ETDEWEB)

Lueck, Jan [Karlsruhe Inst. of Technology (Germany)

2009-07-24

The standard model of elementary particle physics (SM) predicts, besides the top-quark pair production via the strong interaction, also the electroweak production of single top-quarks [19]. Up to now, the Fermilab Tevatron proton-antiproton-collider is the only place to produce and study top quarks emerging from hadron-hadron-collisions. Top quarks were directly observed in 1995 during the Tevatron Run I at a center-of-mass energy of √s = 1.8 TeV simultaneously by the CDF and D0 Collaborations via the strong production of top-quark pairs. Run II of the Tevatron data taking period started 2001 at √s = 1.96 TeV after a five year upgrade of the Tevatron accelerator complex and of both experiments. One main component of its physics program is the determination of the properties of the top quark including its electroweak production. Even though Run II is still ongoing, the study of the top quark is already a successful endeavor, confirmed by dozens of publications from both Tevatron experiments. A comprehensive review of top-quark physics can be found in reference. The reasons for searching for single top-quark production are compelling. As the electroweak top-quark production proceeds via a Wtb vertex, it provides the unique opportunity of the direct measurement of the CKM matrix element |V_tb|, which is expected to be |V_tb| ~ 1 in the SM. Significant deviations from unity could be an indication of a fourth quark generation, a production mode via flavor-changing neutral currents, and other new phenomena, respectively. There are two dominating electroweak top-quark production modes at the Fermilab Tevatron: the t-channel exchange of a virtual W boson striking a b quark and the s-channel production of a timelike W boson via the fusion of two quarks. In proton-antiproton-collisions the third electroweak production mode, the associated Wt production of an on-shell W boson in conjunction with a top quark has a comparatively negligible small

Big Bang Observer and the neutron-star-binary subtraction problem

International Nuclear Information System (INIS)

Cutler, Curt; Harms, Jan

2006-01-01

The Big Bang Observer (BBO) is a proposed space-based gravitational-wave (GW) mission designed primarily to search for an inflation-generated GW background in the frequency range ∼10 -1 Hz-1 Hz. The major astrophysical foreground in this range is gravitational radiation from inspiralling compact binaries. This foreground is expected to be much larger than the inflation-generated background, so to accomplish its main goal, BBO must be sensitive enough to identify and subtract out practically all such binaries in the observable universe. It is somewhat subtle to decide whether BBO's current baseline design is sufficiently sensitive for this task, since, at least initially, the dominant noise source impeding identification of any one binary is confusion noise from all the others (rather than instrumental noise). Here we present a self-consistent scheme for deciding whether BBO's baseline design is indeed adequate for subtracting out the binary foreground. We conclude that the current baseline should be sufficient. However, if BBO's sensitivity were degraded by a factor 2 from the current baseline, then its ability to detect an underlying primordial background would depend critically on the value of ρ th , the threshold signal-to-noise ratio marking the boundary between detectable and undetectable sources. If BBO's sensitivity were degraded by a factor 4 from the current baseline, it could not detect a primordial background below Ω GW ∼10 -15 . It is impossible to perfectly subtract out each of the binary inspiral waveforms, so an important question is how to deal with the 'residual' errors in the post-subtraction data stream. We sketch a strategy of 'projecting out' these residual errors, at the cost of some effective bandwidth. We also provide estimates of the sizes of various post-Newtonian effects in the inspiral waveforms that must be accounted for in the BBO analysis

The effect of Cu{sup II} ions in L-asparagine single crystals

Energy Technology Data Exchange (ETDEWEB)

Santana, Ricardo C., E-mail: santana@ufg.br; Gontijo, Henrique O.; Menezes, Arthur F.; Martins, José A.; Carvalho, Jesiel F., E-mail: carvalho@ufg.br

2016-11-15

We report the synthesis, crystal growth, and spectroscopic characterization of L-asparagine monohydrate (LAM) single crystals doped with CuII. The crystals were successfully grown by slow cooling from a supersaturated aqueous solution up to size of 16×12×2 mm{sup 3};the effect of copper impurities in the crystals morphology was discussed. Electron Paramagnetic Resonance (EPR) was used to calculate the g and hyperfine coupling (A) tensors of the CuII ions (g{sub 1}=2.044, g{sub 2}=2.105, g{sub 3}=2.383and A{sub 1}≈0, A{sub 2}=35, A{sub 3}=108 Gauss). The EPR spectra for certain orientations of the magnetic field suggest that CuII ions are coordinated to two {sup 14}N atoms. Correlating the EPR and optical absorption results, the crystal field and the Cu{sup II} orbital bond parameters were calculated. The results indicate that the paramagnetic center occupies interstitial rhombic distorted site and the ground orbital state for the unpaired electron is the d(x{sup 2}-y{sup 2}).

Digital subtraction in gadolinium-enhanced MR imaging of the brain: a method to reduce contrast dosage

International Nuclear Information System (INIS)

Chan, J.H.M.; Tsui, E.Y.K.; Chan, C.Y.; Lai, K.F.; Cheung, Y.K.; Wong, K.P.C.; Yuen, M.K.; Chau, L.F.; Fong, D.; Mok, C.K.

2002-01-01

The aim of the study was to investigate the feasibility of using digital subtraction in contrast-enhanced MR imaging of the brain to reduce the MR contrast dosage without jeopardizing patient care. Fifty-two patients with intracranial lesions, either intra-axial or extra-axial, detected by computerized tomography were selected for contrast-enhanced MR imaging with half-dose and full-dose of gadopentetate dimeglumine. The half-dose unsubtracted, full-dose unsubtracted, and half-dose subtracted MR images were visually assessed by counting the number of enhancing brain lesions in the images and quantitatively analyzed by computing their lesion contrast-to-background ratios (CBR). The visual conspicuity of the half-dose subtracted MR images was comparable to that of the full-dose unsubtracted MR images (p>0.05), whereas the CBR of the half-dose subtracted images was approximately two to three times higher than that of the full-dose unsubtracted images. The half-dose subtracted T1-weighted spin-echo images might be able to replace the conventional standard-dose T1-weighted spin-echo images in MR imaging of the brain. (orig.)

[Development of a digital chest phantom for studies on energy subtraction techniques].

Science.gov (United States)

Hayashi, Norio; Taniguchi, Anna; Noto, Kimiya; Shimosegawa, Masayuki; Ogura, Toshihiro; Doi, Kunio

2014-03-01

Digital chest phantoms continue to play a significant role in optimizing imaging parameters for chest X-ray examinations. The purpose of this study was to develop a digital chest phantom for studies on energy subtraction techniques under ideal conditions without image noise. Computed tomography (CT) images from the LIDC (Lung Image Database Consortium) were employed to develop a digital chest phantom. The method consisted of the following four steps: 1) segmentation of the lung and bone regions on CT images; 2) creation of simulated nodules; 3) transformation to attenuation coefficient maps from the segmented images; and 4) projection from attenuation coefficient maps. To evaluate the usefulness of digital chest phantoms, we determined the contrast of the simulated nodules in projection images of the digital chest phantom using high and low X-ray energies, soft tissue images obtained by energy subtraction, and "gold standard" images of the soft tissues. Using our method, the lung and bone regions were segmented on the original CT images. The contrast of simulated nodules in soft tissue images obtained by energy subtraction closely matched that obtained using the gold standard images. We thus conclude that it is possible to carry out simulation studies based on energy subtraction techniques using the created digital chest phantoms. Our method is potentially useful for performing simulation studies for optimizing the imaging parameters in chest X-ray examinations.

Moving object detection using background subtraction

CERN Document Server

Shaikh, Soharab Hossain; Chaki, Nabendu

2014-01-01

This Springer Brief presents a comprehensive survey of the existing methodologies of background subtraction methods. It presents a framework for quantitative performance evaluation of different approaches and summarizes the public databases available for research purposes. This well-known methodology has applications in moving object detection from video captured with a stationery camera, separating foreground and background objects and object classification and recognition. The authors identify common challenges faced by researchers including gradual or sudden illumination change, dynamic bac

Practical applications and methods in performing cardiac digital subtraction angiography

International Nuclear Information System (INIS)

Markovic, D.M.; Withrow, S.; Moodie, D.S.

1986-01-01

One of the purposes of this book is to outline the utility of digital subtraction angiography (DSA) in common clinical practice. No text has dealt with the actual physical setup of the room or the patient prior and during a digital subtraction angiographic study at rest and with exercise. This chapter outlines the steps commonly used when cardiac DSA is performed on patients in the authors' laboratory. The authors have learned over the last few years the best way to prepare the patient and the equipment and it is hoped that utilizing this experience, other centers may avoid the mistakes the authors have made in the past and develop new techniques for the future

Subtracted Dispersion Relations for In-medium Meson Correlators in QCD Sum Rules

Energy Technology Data Exchange (ETDEWEB)

Florkowski, W; Broniowski, W [The H. Niewodniczanski Institute of Nuclear Physics, Cracow (Poland)

1999-01-01

We analyze subtracted dispersion relations for meson correlators at finite baryon density and temperature. Such relations are needed for QCD sum rules. We point out that importance of scattering terms, as well as finite, well-defined subtraction constants. Both are necessary for consistency, in particular for the equality of the longitudinal and transverse correlators in the limit of the vanishing three-momentum of mesons relative to the medium. We present detailed calculations in various mesonic channels of the Fermi gas of nucleons. (author)

Perceiving fingers in single-digit arithmetic problems.

Science.gov (United States)

Berteletti, Ilaria; Booth, James R

2015-01-01

In this study, we investigate in children the neural underpinnings of finger representation and finger movement involved in single-digit arithmetic problems. Evidence suggests that finger representation and finger-based strategies play an important role in learning and understanding arithmetic. Because different operations rely on different networks, we compared activation for subtraction and multiplication problems in independently localized finger somatosensory and motor areas and tested whether activation was related to skill. Brain activations from children between 8 and 13 years of age revealed that only subtraction problems significantly activated finger motor areas, suggesting reliance on finger-based strategies. In addition, larger subtraction problems yielded greater somatosensory activation than smaller problems, suggesting a greater reliance on finger representation for larger numerical values. Interestingly, better performance in subtraction problems was associated with lower activation in the finger somatosensory area. Our results support the importance of fine-grained finger representation in arithmetical skill and are the first neurological evidence for a functional role of the somatosensory finger area in proficient arithmetical problem solving, in particular for those problems requiring quantity manipulation. From an educational perspective, these results encourage investigating whether different finger-based strategies facilitate arithmetical understanding and encourage educational practices aiming at integrating finger representation and finger-based strategies as a tool for instilling stronger numerical sense.

Higgs boson production in association with a jet using jettiness subtraction

Directory of Open Access Journals (Sweden)

Radja Boughezal

2015-09-01

Full Text Available We use the recently proposed jettiness-subtraction scheme to provide the complete calculation of Higgs boson production in association with a jet in hadronic collisions through next-to-next-to-leading order in perturbative QCD. This method exploits the observation that the N-jettiness event-shape variable completely describes the singularity structure of QCD when final-state colored particles are present. Our results are in agreement with a recent computation of the gg and qg partonic initial states based on sector-improved residue subtraction. We present phenomenological results for both fiducial cross sections and distributions at the LHC.

Subtraction method of computing QCD jet cross sections at NNLO accuracy

Science.gov (United States)

Trócsányi, Zoltán; Somogyi, Gábor

2008-10-01

We present a general subtraction method for computing radiative corrections to QCD jet cross sections at next-to-next-to-leading order accuracy. The steps needed to set up this subtraction scheme are the same as those used in next-to-leading order computations. However, all steps need non-trivial modifications, which we implement such that that those can be defined at any order in perturbation theory. We give a status report of the implementation of the method to computing jet cross sections in electron-positron annihilation at the next-to-next-to-leading order accuracy.

Subtraction method of computing QCD jet cross sections at NNLO accuracy

Energy Technology Data Exchange (ETDEWEB)

Trocsanyi, Zoltan [University of Debrecen and Institute of Nuclear Research of the Hungarian Academy of Sciences, H-4001 Debrecen P.O.Box 51 (Hungary)], E-mail: Zoltan.Trocsanyi@cern.ch; Somogyi, Gabor [University of Zuerich, Winterthurerstrasse 190, CH-8057 Zuerich (Switzerland)], E-mail: sgabi@physik.unizh.ch

2008-10-15

We present a general subtraction method for computing radiative corrections to QCD jet cross sections at next-to-next-to-leading order accuracy. The steps needed to set up this subtraction scheme are the same as those used in next-to-leading order computations. However, all steps need non-trivial modifications, which we implement such that that those can be defined at any order in perturbation theory. We give a status report of the implementation of the method to computing jet cross sections in electron-positron annihilation at the next-to-next-to-leading order accuracy.

Improvement of temporal and dynamic subtraction images on abdominal CT using 3D global image matching and nonlinear image warping techniques

International Nuclear Information System (INIS)

Okumura, E; Sanada, S; Suzuki, M; Takemura, A; Matsui, O

2007-01-01

Accurate registration of the corresponding non-enhanced and arterial-phase CT images is necessary to create temporal and dynamic subtraction images for the enhancement of subtle abnormalities. However, respiratory movement causes misregistration at the periphery of the liver. To reduce these misregistration errors, we developed a temporal and dynamic subtraction technique to enhance small HCC by 3D global matching and nonlinear image warping techniques. The study population consisted of 21 patients with HCC. Using the 3D global matching and nonlinear image warping technique, we registered current and previous arterial-phase CT images or current non-enhanced and arterial-phase CT images obtained in the same position. The temporal subtraction image was obtained by subtracting the previous arterial-phase CT image from the warped current arterial-phase CT image. The dynamic subtraction image was obtained by the subtraction of the current non-enhanced CT image from the warped current arterial-phase CT image. The percentage of fair or superior temporal subtraction images increased from 52.4% to 95.2% using the new technique, while on the dynamic subtraction images, the percentage increased from 66.6% to 95.2%. The new subtraction technique may facilitate the diagnosis of subtle HCC based on the superior ability of these subtraction images to show nodular and/or ring enhancement

Multivariate spatial condition mapping using subtractive fuzzy cluster means.

Science.gov (United States)

Sabit, Hakilo; Al-Anbuky, Adnan

2014-10-13

Wireless sensor networks are usually deployed for monitoring given physical phenomena taking place in a specific space and over a specific duration of time. The spatio-temporal distribution of these phenomena often correlates to certain physical events. To appropriately characterise these events-phenomena relationships over a given space for a given time frame, we require continuous monitoring of the conditions. WSNs are perfectly suited for these tasks, due to their inherent robustness. This paper presents a subtractive fuzzy cluster means algorithm and its application in data stream mining for wireless sensor systems over a cloud-computing-like architecture, which we call sensor cloud data stream mining. Benchmarking on standard mining algorithms, the k-means and the FCM algorithms, we have demonstrated that the subtractive fuzzy cluster means model can perform high quality distributed data stream mining tasks comparable to centralised data stream mining.

New electronic filtering technique in digital subtraction angiography

Energy Technology Data Exchange (ETDEWEB)

Stacul, F; Pozzi-Mucelli, R; Predonzan, F; Magnaldi, S; Godina, G

1986-01-01

The authors report their experience with a new electronic filtering technique in digital subtraction angiography (DSA). The principles of the technique are reported and the advantages in comparison with conventional filters are stressed (accurate and fast placement without fluoroscopic exposure). The system provided excellent results in about 900 DSA examinations.

EXTENDED ANALYSIS OF THE SPECTRUM OF SINGLY IONIZED CHROMIUM (Cr II)

Energy Technology Data Exchange (ETDEWEB)

Sansonetti, Craig J.; Nave, Gillian [National Institute of Standards and Technology, Gaithersburg, MD 20899 (United States)

2014-08-01

We have made new observations of the spectrum of singly ionized chromium (Cr II) in the region 2850-37900 Å with the National Institute of Standards and Technology 2 m Fourier transform spectrometer. These data extend our previously reported observations in the near-ultra-violet region. We present a comprehensive list of more than 5300 Cr II lines classified as transitions among 456 even and 457 odd levels, 179 of which are newly located in this work. Using highly excited levels of the 3d {sup 4}({sup 5} D)5g, 3d {sup 4}({sup 5} D)6g, and 3d {sup 4}({sup 5}D)6h configurations, we derive an improved ionization energy of 132971.02 ± 0.12 cm{sup –1} (16.486305 ± 0.000015 eV)

Digital subtraction angiography

International Nuclear Information System (INIS)

Gmelin, E.; Arlart, I.P.

1987-01-01

The introduction explains the technical and physical fundamentals of digital radiography, the principles of digital subtraction, and the various filtering methods. The authors then define the requirements to be met by a DSA equipment in terms of technical components and operational performance. A very extensive chapter deals with the indications supporting intravenous or intraarterial DSA and compares the two methods, showing advantages and drawbacks with respect to practical results. Another chapter discusses the applications of DSA for cardiological diagnostics, as e.g. imaging of the coronary arteries or arterial bypasses, and explains the densitometric and planimetric evaluation of the coronary functional processes. The book also discusses less customary applications of DSA such as the sialography or dacryocystography, as well as angiologic examinations in children. The limits of the DSA methods are discussed in the last chapter, together with aspects such as the radiation exposure of the patient, and cost-benefit analyses, and potential future improvements. With 204 figs., 44 tabs [de

Comparison of iodine K-edge subtraction and fluorescence subtraction imaging in an animal system

International Nuclear Information System (INIS)

Zhang, H.; Zhu, Y.; Bewer, B.; Zhang, L.; Korbas, M.; Pickering, I.J.; George, G.N.; Gupta, M.; Chapman, D.

2008-01-01

K-Edge Subtraction (KES) utilizes the discontinuity in the X-ray absorption across the absorption edge of the selected contrast element and creates an image of the projected density of the contrast element from two images acquired just above and below the K-edge of the contrast element. KES has proved to be powerful in coronary angiography, micro-angiography, bronchography, and lymphatic imaging. X-ray fluorescence imaging is a successful technique for the detection of dilute quantities of elements in specimens. However, its application at high X-ray energies (e.g. at the iodine K-edge) is complicated by significant Compton background, which may enter the energy window set for the contrast material's fluorescent X-rays. Inspired by KES, Fluorescence Subtraction Imaging (FSI) is a technique for high-energy (>20 keV) fluorescence imaging using two different incident beam energies just above and below the absorption edge of a contrast element (e.g. iodine). The below-edge image can be assumed as a 'background' image, which includes Compton scatter and fluorescence from other elements. The above-edge image will contain nearly identical spectral content as the below-edge image but will contain the additional fluorescence of the contrast element. This imaging method is especially promising with thick objects with dilute contrast materials, significant Compton background, and/or competing fluorescence lines from other materials. A quality factor is developed to facilitate the comparison. The theoretical value of the quality factor sets the upper limit that an imaging method can achieve when the noise is Poisson limited. The measured value of this factor makes two or more imaging methods comparable. Using the Hard X-ray Micro-Analysis (HXMA) beamline at the Canadian Light Source (CLS), the techniques of FSI and KES were critically compared, with reference to radiation dose, image acquisition time, resolution, signal-to-noise ratios, and quality factor

A Feature Subtraction Method for Image Based Kinship Verification under Uncontrolled Environments

DEFF Research Database (Denmark)

Duan, Xiaodong; Tan, Zheng-Hua

2015-01-01

The most fundamental problem of local feature based kinship verification methods is that a local feature can capture the variations of environmental conditions and the differences between two persons having a kin relation, which can significantly decrease the performance. To address this problem...... the feature distance between face image pairs with kinship and maximize the distance between non-kinship pairs. Based on the subtracted feature, the verification is realized through a simple Gaussian based distance comparison method. Experiments on two public databases show that the feature subtraction method...

Clinical usefulness of subtraction scintigraphy of the liver with Ga-67-citrate and Tc-99m-colloid

International Nuclear Information System (INIS)

Oyamada, H.; Terui, S.; Nagaiwa, K.; Kawai, H.; Fukukita, H.

1983-01-01

Subtraction scintigraphy of the liver with Ga-67-citrate and Tc-99m-colloid was performed for the radionuclide image diagnosis of intrahepatic masses, especially hepatoma. In this method the Tc-99m image was subtracted from the Ga-67 image. After normalizing both images, 4 different factors (0.6, 0.8, 1.0, and 1.2) were applied to the Tc-99m image before the subtraction. Finally, 4 subtraction images with different contrasts were obtained in one X-ray film. This method was found to be very useful in the assessment of intrahepatic focal accumulation of Ga-67, especially in cases with hepatoma, because it eliminated the uncertainty in the former method in which only visual judgment was done

Speech Enhancement by Multichannel Crosstalk Resistant ANC and Improved Spectrum Subtraction

Directory of Open Access Journals (Sweden)

Zeng Qingning

2006-01-01

Full Text Available A scheme combining multichannel crosstalk resistant adaptive noise cancellation (MCRANC algorithm and improved spectrum subtraction (ISS algorithm is presented to enhance noise carrying speech signals. The scheme would permit locating the microphones in close proximity by virtue of using MCRANC which has the capability of removing the crosstalk effect. MCRANC would also permit canceling out nonstationary noise and making the residual noise more stationary for further treatment by ISS algorithm. Experimental results have indicated that this scheme outperforms many commonly used techniques in the sense of SNR improvement and music effect reduction which is an inevitable byproduct of the spectrum subtraction algorithm.

Effects of global signal regression and subtraction methods on resting-state functional connectivity using arterial spin labeling data.

Science.gov (United States)

Silva, João Paulo Santos; Mônaco, Luciana da Mata; Paschoal, André Monteiro; Oliveira, Ícaro Agenor Ferreira de; Leoni, Renata Ferranti

2018-05-16

Arterial spin labeling (ASL) is an established magnetic resonance imaging (MRI) technique that is finding broader applications in functional studies of the healthy and diseased brain. To promote improvement in cerebral blood flow (CBF) signal specificity, many algorithms and imaging procedures, such as subtraction methods, were proposed to eliminate or, at least, minimize noise sources. Therefore, this study addressed the main considerations of how CBF functional connectivity (FC) is changed, regarding resting brain network (RBN) identification and correlations between regions of interest (ROI), by different subtraction methods and removal of residual motion artifacts and global signal fluctuations (RMAGSF). Twenty young healthy participants (13 M/7F, mean age = 25 ± 3 years) underwent an MRI protocol with a pseudo-continuous ASL (pCASL) sequence. Perfusion-based images were obtained using simple, sinc and running subtraction. RMAGSF removal was applied to all CBF time series. Independent Component Analysis (ICA) was used for RBN identification, while Pearson' correlation was performed for ROI-based FC analysis. Temporal signal-to-noise ratio (tSNR) was higher in CBF maps obtained by sinc subtraction, although RMAGSF removal had a significant effect on maps obtained with simple and running subtractions. Neither the subtraction method nor the RMAGSF removal directly affected the identification of RBNs. However, the number of correlated and anti-correlated voxels varied for different subtraction and filtering methods. In an ROI-to-ROI level, changes were prominent in FC values and their statistical significance. Our study showed that both RMAGSF filtering and subtraction method might influence resting-state FC results, especially in an ROI level, consequently affecting FC analysis and its interpretation. Taking our results and the whole discussion together, we understand that for an exploratory assessment of the brain, one could avoid removing RMAGSF to

Simultaneous optical digital half-subtraction and -addition using SOAs and a PPLN waveguide.

Science.gov (United States)

McGeehan, John E; Kumar, Saurabh; Willner, Alan E

2007-04-30

We demonstrate an optical half-subtracter and half-adder module that performs simultaneous bit-wise subtraction and addition of two 5 Gbit/s RZ data streams. We generate Borrow (/X*Y) and Difference/Sum (X plus sign in circleY, or XOR) outputs using cross-gain modulation (XGM) in two parallel SOAs. Taking advantage of the gain saturation inherent to SOAs, we generate two signals, /X*Y, and X*/Y, and combine them using a passive optical coupler to generate the XOR Difference/Sum output. We use difference-frequency-generation-based lambda-conversion in a PPLN waveguide to generate the Carry (X*Y) output. The PPLN waveguide allows bit-synchronous wavelength shifting, is wide-bandwidth, and offers no intrinsic chirp. Our module uses three active elements to perform simultaneous half-subtraction and addition, and carries a maximum power penalty of 1.0 dB.

Improved detection of pulmonary nodules on energy-subtracted chest radiographs with a commercial computer-aided diagnosis software: comparison with human observers

International Nuclear Information System (INIS)

Szucs-Farkas, Zsolt; Patak, Michael A.; Yuksel-Hatz, Seyran; Ruder, Thomas; Vock, Peter

2010-01-01

To retrospectively analyze the performance of a commercial computer-aided diagnosis (CAD) software in the detection of pulmonary nodules in original and energy-subtracted (ES) chest radiographs. Original and ES chest radiographs of 58 patients with 105 pulmonary nodules measuring 5-30 mm and images of 25 control subjects with no nodules were randomized. Five blinded readers evaluated firstly the original postero-anterior images alone and then together with the subtracted radiographs. In a second phase, original and ES images were analyzed by a commercial CAD program. CT was used as reference standard. CAD results were compared to the readers' findings. True-positive (TP) and false-positive (FP) findings with CAD on subtracted and non-subtracted images were compared. Depending on the reader's experience, CAD detected between 11 and 21 nodules missed by readers. Human observers found three to 16 lesions missed by the CAD software. CAD used with ES images produced significantly fewer FPs than with non-subtracted images: 1.75 and 2.14 FPs per image, respectively (p=0.029). The difference for the TP nodules was not significant (40 nodules on ES images and 34 lesions in non-subtracted radiographs, p = 0.142). CAD can improve lesion detection both on energy subtracted and non-subtracted chest images, especially for less experienced readers. The CAD program marked less FPs on energy-subtracted images than on original chest radiographs. (orig.)

X-ray and neutron single crystal diffraction on (NH4)3H(SO4)2. II. Refinement of crystal structure of phase II at room temperature

International Nuclear Information System (INIS)

Reehuis, M.; Wozniak, K.; Dominiak, P.; Smirnov, L.S.; Natkaniec, I.; Baranov, A.I.; Dolbinina, V.V.

2006-01-01

The (NH 4 ) 3 H(SO 4 ) 2 is of special interest due to the possible influence of ammonium ions on a series of phase transitions: I => II => III => IV => V => VII. Earlier, the X-ray single crystal diffraction study of phase II of (NH 4 ) 3 H(SO 4 ) 2 showed that the crystal structure of this compound has two crystallographically independent groups of ammonium ions NH 4 (1) and NH 4 (2), but orientational positions of these ammonium ions were not determined exactly. The refinement of NH 4 (1) and NH 4 (2) orientational positions in phase II is carried out with the help of the X-ray and neutron single crystal diffraction study. The analyses of differential Fourier maps of electron charge density and nuclear density point out the possibility of disordering of NH 4 (2) ammonium ions

Data analysis of x-ray fluorescence holography by subtracting normal component from inverse hologram

International Nuclear Information System (INIS)

Happo, Naohisa; Hayashi, Kouichi; Hosokawa, Shinya

2010-01-01

X-ray fluorescence holography (XFH) is a powerful technique for determining three-dimensional local atomic arrangements around a specific fluorescing element. However, the raw experimental hologram is predominantly a mixed hologram, i.e., a mixture of hologram generated in both normal and inverse modes, which produces unreliable atomic images. In this paper, we propose a practical subtraction method of the normal component from the inverse XFH data by a Fourier transform for the calculated hologram of a model ZnTe cluster. Many spots originating from the normal components could be properly removed using a mask function, and clear atomic images were reconstructed at adequate positions of the model cluster. This method was successfully applied to the analysis of experimental ZnTe single crystal XFH data. (author)

Can approximate mental calculation account for operational momentum in addition and subtraction?

Science.gov (United States)

Knops, André; Dehaene, Stanislas; Berteletti, Ilaria; Zorzi, Marco

2014-01-01

The operational momentum (OM) effect describes a cognitive bias whereby we overestimate the results of mental addition problems while underestimating for subtraction. To test whether the OM emerges from psychophysical characteristics of the mental magnitude representation we measured two basic parameters (Weber fraction and numerical estimation accuracy) characterizing the mental magnitude representation and participants' performance in cross-notational addition and subtraction problems. Although participants were able to solve the cross-notational problems, they consistently chose relatively larger results in addition problems than in subtraction problems, thus replicating and extending previous results. Combining the above measures in a psychophysical model allowed us to partially predict the chosen results. Most crucially, however, we were not able to fully model the OM bias on the basis of these psychophysical parameters. Our results speak against the idea that the OM is due to basic characteristics of the mental magnitude representation. In turn, this might be interpreted as evidence for the assumption that the OM effect is better explained by attentional shifts along the mental magnitude representation during mental calculation.

Detection of aneurysms in subarachnoidal hemorrhage - CT-angiography versus digital subtraction angiography

International Nuclear Information System (INIS)

Roehnert, W.; Haenig, V.; Hietschold, V.; Abolmaali, N.

1998-01-01

Purpose: The value of CT-angiography (CT-A) for the visualization of intracranial aneurysms was more closely defined by comparison with digital subtraction angiography (DSA). Methods: Over a period of 18 months a total of 106 patients in whom a subarachnoidal hemorrhage had been detected on native CT were examined in parallel by spiral CT and DSA. CT-angiography was performed under standardized parameters and included processing with 3D surface reconstructions. Results: In 64 patients (60.4%) at total of 72 aneurysms were detected. In four cases (6.2%) there were two and in two cases (3.1%) even three aneurysms. The findings of DSA and CTA agreed in 98 cases (92.5%). In four patients (3.8%) a false negative results was obtained in CTA and the initial DSA. Conclusions: Digital subtraction angiography must still be considered as the gold standard in the diagnosis of cerebral aneurysms. On account of its excellent spatial delineation of aneurysms and possibilities for exact measurements, CT-angiography represents a valuable, supplementary method - in some cases also an alternative method - to digital subtraction angiography. (orig.) [de

Children's Understanding of the Addition/Subtraction Complement Principle

Science.gov (United States)

Torbeyns, Joke; Peters, Greet; De Smedt, Bert; Ghesquière, Pol; Verschaffel, Lieven

2016-01-01

Background: In the last decades, children's understanding of mathematical principles has become an important research topic. Different from the commutativity and inversion principles, only few studies have focused on children's understanding of the addition/subtraction complement principle (if a - b = c, then c + b = a), mainly relying on verbal…

Intravenous digital subtraction angiography of the lower limbs combined with field movement (2-field DSA)

International Nuclear Information System (INIS)

Fritschy, P.; Terrier, F.

1988-01-01

We evaluated a bolus-chase technique designed to reduce the volume of contrast material and to shorten examination time during intravenous digital subtraction angiography (IV-DSA) of the lower limbs. With this technique, after a single injection of contrast material, two contiguous fields can be sequentially imaged (two-field DAS) using a step translated X-ray tube. 67 patients with peripheral vascular disease were studied. All examinations provided diagnostic information, so that in no instance additional intra-arterial injections were required. With the two-field DSA only 3.49 injections were needed in the average for five fields examined in each patient, resulting in a 30% reduction of contrast agent used. (orig.) [de

Visualization of the renal venous system by renal arteriography with digital subtraction angiography

International Nuclear Information System (INIS)

Nagai, Jun

1989-01-01

The purpose of this study was to obtain vivid and precise images of intrarenal venous branching using DSA for renal arteriography. The type of system used was an ADAC DPS-4100C with 70-80 kVp, and 320 mA, 25-50 msec at 6 frames/sec. The duration was 10 sec and the matrix size was 512x512. In order to retain clear subtracted images of intrarenal venous branching with minimal noise the three frames were selected on the time-density curve of DSA: (Fig.3). 1) a frame on which renal arteries disappear (frame X), 2) the frame with highest renal venous density value as (frame Y), 3) the difference of the nephrogram density between X and Y frames in which only the density of the nephrogram decreases (frame Z). The mask image is the image subtracted by the equation of the weighted averaging method on X and Z frame and is subtracted from the image of Y frame in the final step. By this method, 40 kidneys in 36 patients were studied, and the intrarenal venous branches up to the interlobar vein was clearly demonstrated in 28 of these cases (70%). This method is useful to estimate the extent of intrarenal lesions and detect abnormal renal blood flow compared with conventional temporal subtraction method. (author)

The role of contrast-enhanced digital subtraction MRI in the diagnosis of vertebral metastasic tumors

International Nuclear Information System (INIS)

Xiao Yeyu; Yang Jun; Qi Weili; Liu Qize; Hong Bikai; Wu Renhua

2008-01-01

Objective: To evaluate the contrast-enhanced digital subtraction MRI in the diagnosis of vertebral metastasic tumors. Methods 66 vertebral metastasic tumors in 43 patients were examined with conventional MRI (T 1 WI, STIR and Contrast-enhanced T 1 WI) and contrast-enhanced digital subtraction MR imaging. All lesions were histologically proved. The quantity and characteristic imaging signs (including spiculation, bull eye sign and irregular edge) of lesions were detected separately by different sequences. K independent samples test was used. Results: The detection rates of 35 vertebral metastasic tumors with vertebral morphological changes were same in all MR sequences. But in the other 31 lesions without vertebral morphological changes, the detection rates were different and STIR was the highest in all sequences. Contrast-enhanced digital subtraction MRI was more sensitive than all the conventional MR sequences in finding characteristic imaging signs with statistically significant differences. Conclusion: Contrast enhanced subtraction MRI is an useful and convenient technique which has great value in finding vertebral metastasic tumors and depicting the characteristic imaging signs. (authors)

Magnetization transfer contrast (MTC) and MTC-subtraction: enhancement of cartilage lesions and intracartilaginous degeneration in vitro

International Nuclear Information System (INIS)

Vahlensieck, M.; Dombrowski, F.; Leutner, C.; Wagner, U.; Reiser, M.

1994-01-01

Human articular cartilage from 16 cadaveric or amputated knees was studied using standard magnetic resonance imaging (MRI), on-resonance magnetization transfer contrast (MTC) and MTC-subtraction MRI. Results were compared with subsequent macroscopic and histopathological findings. MTC-subtraction and T2-weighted spin-echo images visualized cartilaginous surface defects with high sensitivity and specificity. MTC and T2-weighted spin-echo images revealed intra-cartilaginous signal loss without surface defects in 80% of the cases, corresponding to an increased collagen concentration. It is concluded that MTC is sensitive to early cartilage degeneration and MTC-subtraction can be helpful in detecting cartilage defects. (orig.)

Perceiving fingers in single-digit arithmetic problems

Directory of Open Access Journals (Sweden)

Ilaria eBerteletti

2015-03-01

Full Text Available In this study, we investigate in children the neural underpinnings of finger representation and finger movement involved in single-digit arithmetic problems. Evidence suggests that finger representation and finger-based strategies play an important role in learning and understanding arithmetic. Because different operations rely on different networks, we compared activation for subtraction and multiplication problems in independently localized finger somatosensory and motor areas and tested whether activation was related to skill. Brain activations from children between 8 and 13 years of age revealed that only subtraction problems significantly activated finger motor areas, suggesting reliance on finger-based strategies. In addition, larger subtraction problems yielded greater somatosensory activation than smaller problems, suggesting a greater reliance on finger representation for larger numerical values. Interestingly, better performance in subtraction problems was associated with lower activation in the finger somatosensory area. Our results support the importance of fine-grained finger representation in arithmetical skill and are the first neurological evidence for a functional role of the somatosensory finger area in proficient arithmetical problem solving, in particular for those problems requiring quantity manipulation. From an educational perspective, these results encourage investigating whether different finger-based strategies facilitate arithmetical understanding and encourage educational practices aiming at integrating finger representation and finger-based strategies as a tool for instilling stronger numerical sense.

Evaluation of the pulmonary vascular bed by digital subtraction angiography

International Nuclear Information System (INIS)

Shikuwa, Masahiro; Asai, Sadahiro; Hara, Shiro; Yamasa, Toshihiko; Miyahara, Yoshiyuki; Hara, Kohei; Nishijima, Kyoji.

1995-01-01

We studied the usefulness of digital subtraction angiography for evaluating the pulmonary capillary bed. Four individuals underwent the procedure. One was a healthy volunteer and the others were patients with chronic pulmonary emphysema. During catheterization, an 8 F balloon catheter was manipulated into the right pulmonary artery. A total of 20 ml of contrast material was injected at a rate of 10 ml/sec at full inspiration. In the normal subject, the capillary bed filled homogeneously and no defect was seen. In the patients, the pulmonary artery was nearly normal, but severe defects were observed in the pulmonary capillaries. Contrast resolvability was greater with digital subtraction pulmonary angiography than with pulmonary perfusion scintigraphy or pulmonary arteriography. This technique makes possible the visual evaluation of the pulmonary capillary bed. (author)

Evaluation of the utility of temporal subtraction images in successive whole-body bone scans: a prospective clinical study

International Nuclear Information System (INIS)

Shiraishi, J.; Appelbaum, D.; Pu, Y.; Engelmann, R.; Li Qiang; Doi, K.

2007-01-01

We have begun a prospective clinical study for evaluating the clinical utility of temporal subtraction images in successive whole-body bone scans. The computerized temporal subtraction technique has been developed in order to highlight interval changes of abnormal lesions due to skeletal metastases, primary bone tumors, osteomyelitis, and fractures. In our initial preliminary results of the prospective study which was started on November 22, 2006 in our hospital, radiologists reported some interval changes which were not recognized in the initial standard readings, but were obvious when temporal subtraction images were viewed. The usefulness of the temporal subtraction images will be investigated in terms of its clinical utility by the prospective clinical study. (orig.)

Dynamic gadolinium-enhanced subtraction MR imaging - a simple technique for the early diagnosis of Legg-Calve-Perthes disease: preliminary results

International Nuclear Information System (INIS)

Sebag, G.; Ducou Le Pointe, H.; Klein, I.; Maiza, D.; Mazda, K.; Bensahel, H.; Hassan, M.

1997-01-01

To determine whether the simple technique of dynamic gadolinium-enhanced subtraction MR imaging, which is available on standard MR units, can detect ischemia of the femoral head in children with early Legg-Calve-Perthes disease (LCP). Bone perfusion of eight hips in four patients (mean age 7.5 years) was studied using dynamic gadolinium-enhanced substraction MR imaging at the onset of proven LCP (with initial negative plain films). Enhancement of subtracted images was compared with that on standard MR images and with bone scintigraphy findings. Subtraction MR imaging depicted ischemia as a widespread absence of enhancement and was in good agreement with bone scintigraphy. The subtraction technique improved the sensitivity and the specificity of MR imaging in two children. Furthermore, subtraction MR imaging allowed recognition of the pattern of early reperfusion. Our preliminary results indicate that dynamic gadolinium-enhanced subtraction MRI is a simple and promising means of early recognition of ischemia in LCP. (orig.)

A multiple regression analysis for accurate background subtraction in 99Tcm-DTPA renography

International Nuclear Information System (INIS)

Middleton, G.W.; Thomson, W.H.; Davies, I.H.; Morgan, A.

1989-01-01

A technique for accurate background subtraction in 99 Tc m -DTPA renography is described. The technique is based on a multiple regression analysis of the renal curves and separate heart and soft tissue curves which together represent background activity. It is compared, in over 100 renograms, with a previously described linear regression technique. Results show that the method provides accurate background subtraction, even in very poorly functioning kidneys, thus enabling relative renal filtration and excretion to be accurately estimated. (author)

Detection of pulmonary nodules on lung X-ray images. Studies on multi-resolutional filter and energy subtraction images

International Nuclear Information System (INIS)

Sawada, Akira; Sato, Yoshinobu; Kido, Shoji; Tamura, Shinichi

1999-01-01

The purpose of this work is to prove the effectiveness of an energy subtraction image for the detection of pulmonary nodules and the effectiveness of multi-resolutional filter on an energy subtraction image to detect pulmonary nodules. Also we study influential factors to the accuracy of detection of pulmonary nodules from viewpoints of types of images, types of digital filters and types of evaluation methods. As one type of images, we select an energy subtraction image, which removes bones such as ribs from the conventional X-ray image by utilizing the difference of X-ray absorption ratios at different energy between bones and soft tissue. Ribs and vessels are major causes of CAD errors in detection of pulmonary nodules and many researches have tried to solve this problem. So we select conventional X-ray images and energy subtraction X-ray images as types of images, and at the same time select ∇ 2 G (Laplacian of Guassian) filter, Min-DD (Minimum Directional Difference) filter and our multi-resolutional filter as types of digital filters. Also we select two evaluation methods and prove the effectiveness of an energy subtraction image, the effectiveness of Min-DD filter on a conventional X-ray image and the effectiveness of multi-resolutional filter on an energy subtraction image. (author)

Relation between thallium-201/iodine 123-BMIPP subtraction and fluorine 18 deoxyglucose polar maps in patients with hypertrophic cardiomyopathy.

Science.gov (United States)

Ito, Y; Hasegawa, S; Yamaguchi, H; Yoshioka, J; Uehara, T; Nishimura, T

2000-01-01

Clinical studies have shown discrepancies in the distribution of thallium-201 and iodine 123-beta-methyl-iodophenylpentadecanoic acid (BMIPP) in patients with hypertrophic cardiomyopathy (HCM). Myocardial uptake of fluorine 18 deoxyglucose (FDG) is increased in the hypertrophic area in HCM. We examined whether the distribution of a Tl-201/BMIPP subtraction polar map correlates with that of an FDG polar map. We normalized to maximum count each Tl-201 and BMIPP bull's-eye polar map of 6 volunteers and obtained a standard Tl-201/BMIPP subtraction polar map by subtracting a normalized BMIPP bull's-eye polar map from a normalized Tl-201 bull's-eye polar map. The Tl-201/BMIPP subtraction polar map was then applied to 8 patients with HCM (mean age 65+/-12 years) to evaluate the discrepancy between Tl-201 and BMIPP distribution. We compared the Tl-201/BMIPP subtraction polar map with an FDG polar map. In patients with HCM, the Tl-201/BMIPP subtraction polar map showed a focal uptake pattern in the hypertrophic area similar to that of the FDG polar map. By quantitative analysis, the severity score of the Tl-201/BMIPP subtraction polar map was significantly correlated with the percent dose uptake of the FDG polar map. These results suggest that this new quantitative method may be an alternative to FDG positron emission tomography for the routine evaluation of HCM.

Digital subtraction CT angiography for the detection of posterior inferior cerebellar artery aneurysms: comparison with digital subtraction angiography

Energy Technology Data Exchange (ETDEWEB)

Chen, Guo Zhong; Luo, Song; Zhou, Chang Sheng; Zhang, Long Jiang; Lu, Guang Ming [Jinling Hospital, Medical School of Nanjing University, Department of Medical Imaging, Nanjing, Jiangsu (China)

2017-09-15

To evaluate the diagnostic accuracy of digital subtraction CT angiography (DS-CTA) in detecting posterior inferior cerebellar artery (PICA) aneurysms with digital subtraction angiography (DSA) as reference standard. A total of 115 patients, including 56 patients diagnosed with PICA aneurysms by CTA or DSA and 59 non-PICA-aneurysm patients were included in this retrospective study. All patients underwent DS-CTA and DSA. The site of PICA aneurysms and the pattern of haemorrhage were analysed. Sensitivity and specificity of DS-CTA without and with combining haemorrhage pattern in diagnosing PICA aneurysms were evaluated on a per patient and per aneurysm basis with DSA. Of 115 patients, 56 patients (48.7%) had 61 PICA aneurysms (size range, 1.1-13.5 mm; mean size, 4.9 ± 2.8 mm) on DSA. The sensitivity and specificity in depicting PICA aneurysms were 89.3% and 96.6% on a per patient basis and 90.2% and 93.4% on a per aneurysm basis, while the corresponding values were 94.6% and 96.6% on a per patient basis and 95.1% and 93.4% on a per aneurysm basis when combining with haemorrhage site. DS-CTA has a high sensitivity and specificity in detecting PICA aneurysms compared with DSA. It may be helpful for clinical diagnosis of PICA aneurysms to combine with haemorrhage sites. (orig.)

Deblurring in digital tomosynthesis by iterative self-layer subtraction

Science.gov (United States)

Youn, Hanbean; Kim, Jee Young; Jang, SunYoung; Cho, Min Kook; Cho, Seungryong; Kim, Ho Kyung

2010-04-01

Recent developments in large-area flat-panel detectors have made tomosynthesis technology revisited in multiplanar xray imaging. However, the typical shift-and-add (SAA) or backprojection reconstruction method is notably claimed by a lack of sharpness in the reconstructed images because of blur artifact which is the superposition of objects which are out of planes. In this study, we have devised an intuitive simple method to reduce the blur artifact based on an iterative approach. This method repeats a forward and backward projection procedure to determine the blur artifact affecting on the plane-of-interest (POI), and then subtracts it from the POI. The proposed method does not include any Fourierdomain operations hence excluding the Fourier-domain-originated artifacts. We describe the concept of the self-layer subtractive tomosynthesis and demonstrate its performance with numerical simulation and experiments. Comparative analysis with the conventional methods, such as the SAA and filtered backprojection methods, is addressed.

Self-mixing differential vibrometer based on electronic channel subtraction

International Nuclear Information System (INIS)

Donati, Silvano; Norgia, Michele; Giuliani, Guido

2006-01-01

An instrument for noncontact measurement of differential vibrations is developed, based on the self-mixing interferometer. As no reference arm is available in the self-mixing configuration, the differential mode is obtained by electronic subtraction of signals from two (nominally equal) vibrometer channels, taking advantage that channels are servo stabilized and thus insensitive to speckle and other sources of amplitude fluctuation. We show that electronic subtraction is nearly as effective as field superposition. Common-mode suppression is 25-30 dB, the dynamic range (amplitude) is in excess of 100 μm, and the minimum measurable (differential) amplitude is 20 nm on aB=10 kHz bandwidth. The instrument has been used to measure vibrations of two metal samples kept in contact, revealing the hysteresis cycle in the microslip and gross-slip regimes, which are of interest in the study of friction induced vibration damping of gas turbine blades for aircraft applications

Femoral head vascularisation in Legg-Calve-Perthes disease: comparison of dynamic gadolinium-enhanced subtraction MRI with bone scintigraphy

International Nuclear Information System (INIS)

Lamer, Sylvie; Dorgeret, Sophie; Brillet, Pierre-Yves; Hassan, Max; Sebag, Guy H.; Khairouni, Abdeslam; Mazda, Keyvan; Bacheville, Eric; Pennecot, Georges F.; Bloch, Juliette

2002-01-01

Heading AbstractBackground. It has been reported that MRI using a dynamic gadolinium-enhanced subtraction technique can allow the early identification of ischaemia and the pattern of revascularisation in Legg-Calve-Perthes (LCP) disease with increased spatial and contrast resolution. Therefore, dynamic gadolinium-enhanced subtraction (DGS) MRI may be a possible non-ionising substitute for bone scintigraphy.Objective. The purpose of this prospective study was to compare DGS MRI and bone scintigraphy in the assessment of femoral head perfusion in LCP disease.Materials and methods. Twenty-six DGS MR images and bone scintigraphies of 25 hips in 23 children were obtained at different stages of LCP disease; three stage I, 12 stage II, six stage III and five stage IV (Waldenstroem classification). The extent of necrosis, epiphyseal revascularisation pathways (lateral pillar, medial pillar, and/or transphyseal perfusion) and metaphyseal changes were analysed.Results. Total agreement between both techniques was noted in the depiction of epiphyseal necrosis (kappa=1), and metaphyseal abnormalities (kappa=0.9). DGS MRI demonstrated better revascularisation in the lateral (kappa=0.62) and medial pillars (kappa=0.52). The presence of basal transphyseal reperfusion was more conspicuous with MRI.Conclusions. DGS MRI allows early detection of epiphyseal ischaemia and accurate analysis of the different revascularisation patterns. These changes are directly related to the prognosis of LCP disease and can aid therapeutic decision making. (orig.)

Accuracy of digital subtraction radiography in combination with a contrast media in assessment of proximal caries depth

Directory of Open Access Journals (Sweden)

Farzad Esmaeili

2008-07-01

Full Text Available Background and aims. Radiography is used to diagnose the demineralization process and carious lesions; however, conventional radiography and direct digital images do not show these lesions when the amount of demineralization is less than 40%. Digital subtraction radiography has recently been used to improve the diagnostic quality of these lesions. The purpose of this study was to compare the caries depth estimated by digital subtraction radiography in combination with barium sulfate in diagnosing proximal dental caries with histopathologic evaluation. Materials and methods. In this study 30 molars and premolars (24 demineralized lesions with cavity, 8 without cavity were studied. Direct digital images were taken (kVp: 68, mA: 8; t: 0.12 for premolars and t: 0.16 for molars whereas the position of X-ray tube and CCD receptor and teeth was fixed. To prepare the second images 135 gr/L barium sulfate was used. The images obtained with the same exposure and geometry and then subtracted. The depth of the lesions in direct digital and subtracted images were assessed and compared with the depth measured in histopathologic assessments. Results. The mean depths (± SD of the lesions were 1.80 ± 0.77 mm in direct digital radiography, 2.32 ± 0.76 mm in subtracted images after barium sulfate treatment, and 2.51 ± 0.43 mm in histopathologic sections. The statistical difference between direct digital radiography and the other methods was significant (P < 0.05. However, the differences were not statistically significant between subtracted images and histopathologic sections. The average intra-class correlation coefficient was 0.7241 (CI: 95%. Conclusion. The present study has demonstrated that digital subtraction radiography images have the potential to measure the depth of proximal caries with no significant difference with histopathologic evaluation.

An evaluation of the subtraction photoshop software accuracy to detect minor changes in optical density by radiovisiography

Directory of Open Access Journals (Sweden)

Talaeipour AR.

2004-06-01

Full Text Available Statement of Problem: Subtraction is a newly presented radiography technique to detect minor density"nchanges that are not visible by conventional radiography."nPurpose: The aim of this In-vitro study was to evaluate the efficacy of photoshop subtraction software for"ndetecting minor density changes between two dental images."nMaterials and Methods: In this research, five dried human mandibles were held in fixed position while thin"naluminium sheets were superimposed on each mandible on the 1th and 2nd molar teeth regions."nA reference image, without aluminium sheet placement, was obtained from each mandible subsequently series"nconsist of 20 images with aluminium sheets, ranging from 50p. to "5Q0"x were recorded by radiovisiography"n(RVG system. Initial images were subtracted from subsequent ones by Photoshop subtraction software. The"ndifference in density between the two images at the 1st and 2nd molar sites was related to the aluminium"nsheets. The optical density of aluminium sheets was determined by densitometer."nResults: In the present study, 6.6% of the optical density changes of the minimum aluminium thickness as"n300u. could be detected by photoshop software software."nConclusion: The findings of this study showed that the accuracy of photoshop subtraction software was equal"nto that of the conventional subtraction softwares. Additionally, the accuracy of this software was proved to be"nsuitable for clinical investigations of small localized changes in alveolar bone.

Digital subtraction angiography in the diagnosis of Fallot's tetralogy

International Nuclear Information System (INIS)

Ivanitskij, A.V.; Tereshkin, Ya.A.; Sobolev, A.V.; Stolyar, V.L.; Slyunyastikov, M.A.

1995-01-01

The authors analyze the efficacy of digital subtraction angiography (DSA) in the diagnosis of Fallot's tetralogy (FT); this method helps simplity and cut down their scope of investigations but does not deteriorate their informative value. DSA findings in 120 patients with TF are analyzed. 5 refs.; 6 figs

Competitive adsorption of copper(II), cadmium(II), lead(II) and zinc(II) onto basic oxygen furnace slag

International Nuclear Information System (INIS)

Xue Yongjie; Hou Haobo; Zhu Shujing

2009-01-01

Polluted and contaminated water can often contain more than one heavy metal species. It is possible that the behavior of a particular metal species in a solution system will be affected by the presence of other metals. In this study, we have investigated the adsorption of Cd(II), Cu(II), Pb(II), and Zn(II) onto basic oxygen furnace slag (BOF slag) in single- and multi-element solution systems as a function of pH and concentration, in a background solution of 0.01 M NaNO 3 . In adsorption edge experiments, the pH was varied from 2.0 to 13.0 with total metal concentration 0.84 mM in the single element system and 0.21 mM each of Cd(II), Cu(II), Pb(II), and Zn(II) in the multi-element system. The value of pH 50 (the pH at which 50% adsorption occurs) was found to follow the sequence Zn > Cu > Pb > Cd in single-element systems, but Pb > Cu > Zn > Cd in the multi-element system. Adsorption isotherms at pH 6.0 in the multi-element systems showed that there is competition among various metals for adsorption sites on BOF slag. The adsorption and potentiometric titrations data for various slag-metal systems were modeled using an extended constant-capacitance surface complexation model that assumed an ion-exchange process below pH 6.5 and the formation of inner-sphere surface complexes at higher pH. Inner-sphere complexation was more dominant for the Cu(II), Pb(II) and Zn(II) systems

Competitive adsorption of copper(II), cadmium(II), lead(II) and zinc(II) onto basic oxygen furnace slag

Energy Technology Data Exchange (ETDEWEB)

Xue Yongjie [School of Resource and Environment Science, Wuhan University, Hubei, Wuhan (China); Wuhan Kaidi Electric Power Environmental Protection Co. Ltd., Hubei, Wuhan (China)], E-mail: xueyj@mail.whut.edu.cn; Hou Haobo; Zhu Shujing [School of Resource and Environment Science, Wuhan University, Hubei, Wuhan (China)

2009-02-15

Polluted and contaminated water can often contain more than one heavy metal species. It is possible that the behavior of a particular metal species in a solution system will be affected by the presence of other metals. In this study, we have investigated the adsorption of Cd(II), Cu(II), Pb(II), and Zn(II) onto basic oxygen furnace slag (BOF slag) in single- and multi-element solution systems as a function of pH and concentration, in a background solution of 0.01 M NaNO{sub 3}. In adsorption edge experiments, the pH was varied from 2.0 to 13.0 with total metal concentration 0.84 mM in the single element system and 0.21 mM each of Cd(II), Cu(II), Pb(II), and Zn(II) in the multi-element system. The value of pH{sub 50} (the pH at which 50% adsorption occurs) was found to follow the sequence Zn > Cu > Pb > Cd in single-element systems, but Pb > Cu > Zn > Cd in the multi-element system. Adsorption isotherms at pH 6.0 in the multi-element systems showed that there is competition among various metals for adsorption sites on BOF slag. The adsorption and potentiometric titrations data for various slag-metal systems were modeled using an extended constant-capacitance surface complexation model that assumed an ion-exchange process below pH 6.5 and the formation of inner-sphere surface complexes at higher pH. Inner-sphere complexation was more dominant for the Cu(II), Pb(II) and Zn(II) systems.

Competitive adsorption of copper(II), cadmium(II), lead(II) and zinc(II) onto basic oxygen furnace slag.

Science.gov (United States)

Xue, Yongjie; Hou, Haobo; Zhu, Shujing

2009-02-15

Polluted and contaminated water can often contain more than one heavy metal species. It is possible that the behavior of a particular metal species in a solution system will be affected by the presence of other metals. In this study, we have investigated the adsorption of Cd(II), Cu(II), Pb(II), and Zn(II) onto basic oxygen furnace slag (BOF slag) in single- and multi-element solution systems as a function of pH and concentration, in a background solution of 0.01M NaNO(3). In adsorption edge experiments, the pH was varied from 2.0 to 13.0 with total metal concentration 0.84mM in the single element system and 0.21mM each of Cd(II), Cu(II), Pb(II), and Zn(II) in the multi-element system. The value of pH(50) (the pH at which 50% adsorption occurs) was found to follow the sequence Zn>Cu>Pb>Cd in single-element systems, but Pb>Cu>Zn>Cd in the multi-element system. Adsorption isotherms at pH 6.0 in the multi-element systems showed that there is competition among various metals for adsorption sites on BOF slag. The adsorption and potentiometric titrations data for various slag-metal systems were modeled using an extended constant-capacitance surface complexation model that assumed an ion-exchange process below pH 6.5 and the formation of inner-sphere surface complexes at higher pH. Inner-sphere complexation was more dominant for the Cu(II), Pb(II) and Zn(II) systems.

Tumor scintigraphy by the method for subtracting the initial image with technetium-99m labeled antibody

International Nuclear Information System (INIS)

Karube, Yoshiharu; Katsuno, Kentaro; Ito, Sanae; Matsunaga, Kazuhisa; Takata, Jiro; Kuroki, Masahide; Murakami, Masaaki; Matsuoka, Yuji

1999-01-01

The method for subtracting the initial image from the localization image was evaluated for radioimmunoscintigraphy of tumors with technetium-99m (Tc-99m) labeled antibodies. Monoclonal antibodies were parental mouse and mouse-human chimeric antibodies to carcinoembryonic antigen (CEA), designated F11-39 and ChF11-39, respectively, both of which have been found to discriminate CEA in tumor tissues from the CEA-related antigens. After reduction of the intrinsic disulfide bonds, these antibodies were labeled with Tc-99m. In vivo studies were performed on athymic nude mice bearing the human CEA-producing gastric carcinoma xenografts. Though biodistribution results showed selective and progressive accumulation of Tc-99m labeled antibodies at the tumor site, high radioactivity in blood was inappropriate for scintigraphic visualization of the tumors within a few hours. We examined the subtraction of the initial Tc-99m image from the Tc-99m localization image after a few hours. Subtracted images of the same count reflected the in vivo behavior of the Tc-99m radioactivity. The subtracted scintigrams revealed excellent tumor images with no significant extrarenal background. Visualization of the tumor site was dependent on antigen-specific binding and nonspecific exudation. These results demonstrate that a method of subtraction of the initial image may serve as a potentially useful diagnostic method for an abnormal site for agents with a low pharmacokinetic value. (author)

Counting the mismatches - lung ventilation/perfusion subtraction index

International Nuclear Information System (INIS)

Anderson, T.C.; Evans, S.G.; Larcos, G.; Farlow, D.C.

1998-01-01

Full text: There is potential for interobserver variability in interpretation of ventilation/perfusion (V/Q) scans. Objective quantification of V/Q mismatch could be useful. Thus, the aim of this study is to determine the validity of image subtraction in a group of 27 patients (11 men, 8 women; mean age 59.4 years [range 21-81 years])investigated by V/Q scans for suspected pulmonary emboli. A standard 6 view V/Q scan was obtained with two cobalt markers used on the anterior and posterior surfaces for image alignment. Ventilation images were normalised to the perfusion using an area of normal ventilation and perfusion. With the use of automated, and if required, manual alignment, perfusion images were subtracted from ventilation, with a median filter applied. A summed index of mismatch for each lung scan was calculated from the difference. This index was then retrospectively compared to the result reported by one of four experienced physicians. Two patients with chronic obstructive airways disease were excluded from analysis. We conclude that high probability V/Q scans can be differentiated from low probability studies using this index; further prospective investigation in a larger cohort is warranted

Determination of the kalium-subtracted total beta in food

International Nuclear Information System (INIS)

Liu Guofan

1985-01-01

A procedure for measuring the kalium-subtracted total beta in food can be applied to estimating the contamination of beta nuclides except 40 K. The procedure, calculating formula, and some experiences in practice are described in this paper. The method is simple, rapid, and very useful to food contamination monitoring

Continuous-variable measurement-device-independent quantum key distribution with virtual photon subtraction

Science.gov (United States)

Zhao, Yijia; Zhang, Yichen; Xu, Bingjie; Yu, Song; Guo, Hong

2018-04-01

The method of improving the performance of continuous-variable quantum key distribution protocols by postselection has been recently proposed and verified. In continuous-variable measurement-device-independent quantum key distribution (CV-MDI QKD) protocols, the measurement results are obtained from untrusted third party Charlie. There is still not an effective method of improving CV-MDI QKD by the postselection with untrusted measurement. We propose a method to improve the performance of coherent-state CV-MDI QKD protocol by virtual photon subtraction via non-Gaussian postselection. The non-Gaussian postselection of transmitted data is equivalent to an ideal photon subtraction on the two-mode squeezed vacuum state, which is favorable to enhance the performance of CV-MDI QKD. In CV-MDI QKD protocol with non-Gaussian postselection, two users select their own data independently. We demonstrate that the optimal performance of the renovated CV-MDI QKD protocol is obtained with the transmitted data only selected by Alice. By setting appropriate parameters of the virtual photon subtraction, the secret key rate and tolerable excess noise are both improved at long transmission distance. The method provides an effective optimization scheme for the application of CV-MDI QKD protocols.

Venous digital subtraction angiography of the renal arteries in hypertensive patients

International Nuclear Information System (INIS)

Brecht, G.; Harder, T.; Franken, T.

1984-01-01

We carried out 1890 venous digital subtraction angiograms; this included 113 patients with hypertension in order to exclude renal artery stenosis. On four occasions it was used following surgery on a renal artery. Renal artery stenosis or occlusion was demonstrated in twelve patients, and other vascular diseases or anomalies were found in 24. Two abnormal renal arteries were found following renal artery surgery. The results are compared with smaller groups of patients examined by DSA, and with the results of conventional subtraction methods reported in the literature. In only eight patients (6.8%) DSA provided insufficient information and had to be supplemented by aortography. The method has proved to be a valuable and simple screening method for the investigation of hypertension. (orig.) [de

[X-ray semiotics of sialolithiasis in functional digital subtraction sialography].

Science.gov (United States)

Iudin, L A; Kondrashin, S A; Afanas'ev, V V; Shchipskiĭ, A V

1995-01-01

Twenty-seven patients with sialolithiasis were examined using functional subtraction sialography developed by the authors. Differential diagnostic signs characterizing the degree of involvement of the salivary gland were defined. High efficacy of the method helps correctly plan the treatment strategy.

PCA-based approach for subtracting thermal background emission in high-contrast imaging data

Science.gov (United States)

Hunziker, S.; Quanz, S. P.; Amara, A.; Meyer, M. R.

2018-03-01

Aims.Ground-based observations at thermal infrared wavelengths suffer from large background radiation due to the sky, telescope and warm surfaces in the instrument. This significantly limits the sensitivity of ground-based observations at wavelengths longer than 3 μm. The main purpose of this work is to analyse this background emission in infrared high-contrast imaging data as illustrative of the problem, show how it can be modelled and subtracted and demonstrate that it can improve the detection of faint sources, such as exoplanets. Methods: We used principal component analysis (PCA) to model and subtract the thermal background emission in three archival high-contrast angular differential imaging datasets in the M' and L' filter. We used an M' dataset of β Pic to describe in detail how the algorithm works and explain how it can be applied. The results of the background subtraction are compared to the results from a conventional mean background subtraction scheme applied to the same dataset. Finally, both methods for background subtraction are compared by performing complete data reductions. We analysed the results from the M' dataset of HD 100546 only qualitatively. For the M' band dataset of β Pic and the L' band dataset of HD 169142, which was obtained with an angular groove phase mask vortex vector coronagraph, we also calculated and analysed the achieved signal-to-noise ratio (S/N). Results: We show that applying PCA is an effective way to remove spatially and temporarily varying thermal background emission down to close to the background limit. The procedure also proves to be very successful at reconstructing the background that is hidden behind the point spread function. In the complete data reductions, we find at least qualitative improvements for HD 100546 and HD 169142, however, we fail to find a significant increase in S/N of β Pic b. We discuss these findings and argue that in particular datasets with strongly varying observing conditions or

Intraarterial digital subtraction angiography in neuroradiology

International Nuclear Information System (INIS)

Zeumer, H.

1987-01-01

Neuroradiology always could make best use of subtraction methods, due to the relative immobility and constant shape of the skull. Arterial DSA now has extended the potential uses while reducing the patient's radiation exposure, the contrast medium dosage and osmolarity. The considerable cut-back in time required for invasive examination has reduced the risk of diagnostic and therapeutic measures. The advantages consisting of immediate image display with high contrast resolution in most of the diagnostic tasks counterbalance the disadvantage of low focal resolution of the DSA in neuroradiology. Interventional neuroradiology today cannot do without i.a. DSA. (orig.) [de

Aggression-related brain function assessed with the Point Subtraction Aggression Paradigm in fMRI

DEFF Research Database (Denmark)

Skibsted, Anine P; Cunha-Bang, Sofi da; Carré, Justin M

2017-01-01

The Point Subtraction Aggression Paradigm (PSAP) measures aggressive behavior in response to provocations. The aim of the study was to implement the PSAP in a functional neuroimaging environment (fMRI) and evaluate aggression-related brain reactivity including response to provocations and associa......The Point Subtraction Aggression Paradigm (PSAP) measures aggressive behavior in response to provocations. The aim of the study was to implement the PSAP in a functional neuroimaging environment (fMRI) and evaluate aggression-related brain reactivity including response to provocations...... and associations with aggression within the paradigm. Twenty healthy participants completed two 12-min PSAP sessions within the scanner. We evaluated brain responses to aggressive behavior (removing points from an opponent), provocations (point subtractions by the opponent), and winning points. Our results showed...... with the involvement of these brain regions in emotional and impulsive behavior. Striatal reactivity may suggest an involvement of reward during winning and stealing points....

Effect of relative nanohole position on colour purity of ultrathin plasmonic subtractive colour filters

International Nuclear Information System (INIS)

Sun, L B; Hu, X L; Zhang, D X; Zeng, Beibei; Wang, L S; Yang, S M; Tai, R Z; Fecht, H J; Jiang, J Z

2015-01-01

Plasmonic subtractive color filters through patterning periodic nanostructures on ultrathin Ag films deposited on a glass substrate, exhibiting good durability, simple fabrication, and flexible color tunability, have attracted considerable attention due to their tremendous potential applications. While previous studies have mainly focused on their extraordinary physical mechanisms, color purity, which is another key parameter for high quality imaging applications, has been much less investigated. In this work, we demonstrate that the relative position of nanoholes patterned on ultrathin Ag films can largely affect the color purity of plasmonic subtractive color filters. The calculated results agree reasonably well with the experimental data, revealing that the purity of subtractive colors can be improved by changing the nanohole arrays from square lattice to triangular lattice without reducing transmission at visible frequencies. In addition, underlying mechanisms are clarified by systematically analyzing the dominant valley in transmission spectra. (paper)

A study on computer-aided diagnosis based on temporal subtraction of sequential chest radiographs (in Japanese)

International Nuclear Information System (INIS)

Kano, Akiko

2001-01-01

An automated digital image subtraction technique for use with pairs of temporally sequential chest radiographs has been developed to aid radiologists in the detection of interval changes. Automated image registration based on nonlinear geometric warping is performed prior to subtraction in order to deal with complicated radiographic misregistration. Processing includes global matching, to achieve rough registration between the entire lung fields in the two images, and local matching, based on a cross-correlation method, to determine local shift values for a number of small regions. A proper warping of x,y-coordinates is determined by fitting two-dimensional polynomials to the distributions of the shift values. One image is warped and then subtracted from the other. The resultant subtraction images were able to enhance the conspicuity of various types of interval changes. Improved global matching based on a weighted template matching method achieved robust registration even with photofluorographs taken in chest mass screening programs, which had previously presented us with a relatively large number of poor-registration images. The new method was applied to 129 pairs of chest mass screening images, and offered registration accuracy as good as manual global matching. An observer test using 114 cases including 57 lung cancer cases presented better sensitivity and specificity on average compared to conventional comparison readings. In addition, newly developed image processing that eliminates the rib edge artifacts in subtraction images was applied to 26 images having pathological interval changes; results showed the potential for application to automated schemes for the detection of interval change patterns. With its capacity to improve the diagnostic accuracy of chest radiographs, the chest temporal subtraction technique promises to become an important element of computer-aided diagnosis (CAD) systems

Construction and identification of subtracted cDNA library in bone marrow cells of radon-exposed mice

International Nuclear Information System (INIS)

Li Jianxiang; Nie Jihua; Tong Jian; Fu Chunling; Zhou Jianwei

2008-01-01

Objective: To construct and identify subtracted cDNA library in bone marrow cells of mice exposed to radon inhalation. Methods: Adult male BALB/c mice, weighing 18-22 g, were placed in a multi- functional radon chamber. One group of mice was exposed to radon up to the accumulative dose of 105 work level month (WLM). The control group of mice was housed in a room with an accumulative dose of 1 WLM. To construct a subtracted cDNA library enriched with differentially expressed genes, the SMART technique and the suppression subtractive hybridization were performed. The obtained forward and reverse cDNA fragments were directly inserted into pMD18-T vector and transformed into E. coli JM109. The inserting cDNA fragments were screened by the blue-and-white blot screening and nested PCR of bacterium liquid. Results: The 244 of 285 white bacteria clones obtained randomly were positive clones contained 100-1100 bp inserted cDNA fragments. Conclusions: The forward and reverse subtracted cDNA library in bone marrow cells of mice exposed to radon inhalation is successfully constructed. (authors)

Enhancing quantum entanglement for continuous variables by a coherent superposition of photon subtraction and addition

Energy Technology Data Exchange (ETDEWEB)

Lee, Su-Yong; Kim, Ho-Joon [Department of Physics, Texas A and M University at Qatar, P.O. Box 23874, Doha (Qatar); Ji, Se-Wan [School of Computational Sciences, Korea Institute for Advanced Study, Seoul 130-012 (Korea, Republic of); Nha, Hyunchul [Department of Physics, Texas A and M University at Qatar, P.O. Box 23874, Doha (Qatar); Institute fuer Quantenphysik, Universitaet Ulm, D-89069 Ulm (Germany)

2011-07-15

We investigate how the entanglement properties of a two-mode state can be improved by performing a coherent superposition operation ta+ra{sup {dagger}} of photon subtraction and addition, proposed by Lee and Nha [Phys. Rev. A 82, 053812 (2010)], on each mode. We show that the degree of entanglement, the Einstein-Podolsky-Rosen-type correlation, and the performance of quantum teleportation can be all enhanced for the output state when the coherent operation is applied to a two-mode squeezed state. The effects of the coherent operation are more prominent than those of the mere photon subtraction a and the addition a{sup {dagger}} particularly in the small-squeezing regime, whereas the optimal operation becomes the photon subtraction (case of r=0) in the large-squeezing regime.

Sky subtraction at the Poisson limit with fibre-optic multiobject spectroscopy

Science.gov (United States)

Sharp, R.; Parkinson, H.

2010-11-01

We report on the limitations of sky-subtraction accuracy for long-duration fibre-optic multiobject spectroscopy of faint astronomical sources during long-duration exposures. We show that while standard sky subtraction techniques yield accuracies consistent with the Poisson noise limit for exposures of 1h duration, there are large-scale systematic defects that inhibit the sensitivity gains expected on the summation of longer duration exposures. For the AAOmega system at the Anglo-Australian Telescope, we identify a limiting systematic sky-subtraction accuracy, which is reached after integration times of 4-10h. We show that these systematic defects can be avoided through the use of the fibre nod-and-shuffle (N+S) observing mode, but with a potential cost in observing efficiency. Finally, we demonstrate that these disadvantages can be overcome through the application of a Principal Components Analysis (PCA) sky-subtraction routine. Such an approach minimize systematic residuals across long-duration exposures, allowing deep integrations. We apply the PCA approach to over 200h of on-sky observations and conclude that for the AAOmega system, the residual error in long-duration observations falls at a rate proportional to τ-0.32 in contrast to the τ-0.5 rate expected from theoretical considerations. With this modest rate of decline, the PCA approach represents a more efficient mode of observation than the N+S technique for observations in the sky limited regime with durations of 10-100h (even before accounting for the additional signal-to-noise ratio and targeting efficiency losses often associated with the N+S technique). This conclusion has important implications for the observing strategies of the next generation of fibre-optics redshift surveys with existing facilities as well as design implications for fibre-optic systems destined for new facilities. It argues against the use of the inherently inefficient N+S technique for faint object fibre-optic survey

Clinical evaluation of dual-energy bone removal in CT angiography of the head and neck: comparison with conventional bone-subtraction CT angiography

International Nuclear Information System (INIS)

Deng, K.; Liu, C.; Ma, R.; Sun, C.; Wang, X.-M.; Ma, Z.-T.; Sun, X.-L.

2009-01-01

Aim: To evaluate the bone-subtraction effect of dual-energy bone removal in computed tomography angiography (CTA) of the head and neck in comparison with conventional bone-subtraction CTA. Material and Methods: The study comprised 52 patients who were divided into two groups at random, and examined using dual-source CT for head and neck CTA. Dual-energy bone removal CTA and conventional bone-subtraction CTA were applied to each of the two groups, respectively. The bone subtraction was performed automatically in both methods. Vascular structures, as well as brain tissue remained visible. The subtracted images were further processed with maximum intensity projection (MIP) and volume-rendering technique (VRT) for image evaluation. Two experienced radiologists reviewed the resulting subtracted and non-subtracted volume data with respect to the delineation and detection of image quality and vascular pathology. Results: The means of the weighted CT dose index (CTDIvol) for bone-removal dual-energy CTA and conventional bone-subtraction CTA were 20.56 ± 0.01 mGy and 25.57 ± 0.56 mGy, respectively. There was a significant difference between them. The percentage of carotid and vertebral arteries and all other vessels that could be successfully assessed with these two methods were 87.8, 68, and 83%, and 93.5, 91.8, and 92.6%, respectively. There were no significant differences in the visualization of the carotid arteries; however, there were significant differences in the visualization of the vertebral arteries. Conclusion: Compared with conventional bone-subtraction CTA, dual-energy bone-removal CTA had a lower radiation dose. It eliminated most bones in the head and neck successfully; however, the bone subtraction effect around the vertebral artery was unsatisfactory. Dual-energy bone-removal CTA provides a new method for detecting vascular diseases in routine clinical work.

Formation of a dinuclear copper(II) complex through the cleavage of CSingle-Bond' name='Single-Bond' value='Single-Bond'/>N bond of 1-benzoyl-3-(pyridin-2-yl)-1H-pyrazole

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Shardin, Rosidah; Pui, Law Kung; Yamin, Bohari M. [School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, UKM 43600 Bangi, Selangor (Malaysia); Kassim, Mohammad B. [School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, UKM 43600 Bangi, Selangor, Malaysia and Fuel Cell Institute, Universiti Kebangsaan Malaysia, UKM 43600 Bangi, Selangor (Malaysia)

2014-09-03

A simple mononuclear octahedral copper(II) complex was attempted from the reaction of three moles of 1-benzoyl-3-(pyridin-2-yl)-1H-pyrazole and one mole of copper(II) perchlorate hexahydrate in methanol. However, the product of the reaction was confirmed to be a dinuclear copper(II) complex with μ-(3-(pyridin-2-yl)-pyrazolato) and 3-(pyridin-2-yl)-1H-pyrazole ligands attached to each of the Cu(II) centre atom. The copper(II) ion assisted the cleavage of the C{sub benzoyl}Single-Bond' name='Single-Bond' value='Single-Bond'/>N bond afforded a 3-(pyridin-2-yl)-1H-pyrazole molecule. Deprotonation of the 3-(pyridin-2-yl)-1H-pyrazole gave a 3-(pyridin-2-yl)-pyrazolato, which subsequently reacted with the Cu(II) ion to give the (3-(pyridin-2-yl)-pyrazolato)(3-(pyridin-2-yl)-1H-pyrazole)Cu(II) product moiety. The structure of the dinuclear complex was confirmed by x-ray crystallography. The complex crystallized in a monoclinic crystal system with P2(1)/n space group and cell dimensions of a = 12.2029(8) Å, b = 11.4010(7) Å, c = 14.4052(9) Å and β = 102.414(2)°. The compound was further characterized by mass spectrometry, CHN elemental analysis, infrared and UV-visible spectroscopy and the results concurred with the x-ray structure. The presence of d-d transition at 671 nm (ε = 116 dm{sup 3} mol{sup −1} cm{sup −1}) supports the presence of Cu(II) centres.

Similarity renormalization group evolution of N N interactions within a subtractive renormalization scheme

Directory of Open Access Journals (Sweden)

Durães F.O.

2010-04-01

Full Text Available We apply the similarity renormalization group (SRG approach to evolve a nucleon-nucleon (N N interaction in leading-order (LO chiral effective field theory (ChEFT, renormalized within the framework of the subtracted kernel method (SKM. We derive a fixed-point interaction and show the renormalization group (RG invariance in the SKM approach. We also compare the evolution of N N potentials with the subtraction scale through a SKM RG equation in the form of a non-relativistic Callan-Symanzik (NRCS equation and the evolution with the similarity cutoff through the SRG transformation.

Quantitative digital subtraction radiography in the assessment of external apical root resorption induced by orthodontic therapy: a retrospective study.

Science.gov (United States)

Sunku, Raghavendra; Roopesh, R; Kancherla, Pavan; Perumalla, Kiran Kumar; Yudhistar, Palla Venkata; Reddy, V Sridhar

2011-11-01

The objective of this study was to evaluate density changes around the apices of teeth during orthodontic treatment by using digital subtraction radiography to measure the densities around six teeth (maxilla central incisors, lateral incisors, and canines) before and after orthodontic treatment in 36 patients and also assess treatment variables and their coorelation with root resorption. A total of 36 consecutive patient files were selected initially. The selected patients presented with a class I or II relationship and were treated with or without premolar extractions and fixed appliances. Some class II patients were treated additionally with extraoral forces or functional appliances. External apical root resorption (EARR) per tooth in millimeters was calculated and was also expressed as a percentage of the original root length. Image reconstruction and subtraction were performed using the software Regeemy Image Registration and Mosaicing (version 0.2.43-RCB, DPI-INPE, Sao Jose dos Campos, Sao Paulo, Brazil) by a single operator. A region of interest (ROI) was defined in the apical third of the root and density calibration was made in Image J® using enamel (gray value = 255) as reference in the same image. The mean gray values in the ROIs were reflective of the change in the density values between the two images. The root resorption of the tooth and the factors of malocclusion were analyzed with a one-way ANOVA. An independent t-test was performed to compare the mean amount of resorption between male and female, between extraction and nonextraction cases. The density changes after orthodontic treatment were analyzed using the Wilcoxon signedrank test. In addition, the density changes in different teeth were analyzed using the Kruskal-Wallis test. The cut-off for statistical significance was a p-value of 0.05. All the statistical analyses were carried out using SPSS (version 13.0 for Windows, Chicago, IL, USA). Gender, the age at which treatment was started and

Adiabatic regularization of the power spectrum in nonminimally coupled general single-field inflation

Science.gov (United States)

Alinea, Allan L.; Kubota, Takahiro

2018-03-01

We perform adiabatic regularization of power spectrum in nonminimally coupled general single-field inflation with varying speed of sound. The subtraction is performed within the framework of earlier study by Urakawa and Starobinsky dealing with the canonical inflation. Inspired by Fakir and Unruh's model on nonminimally coupled chaotic inflation, we find upon imposing near scale-invariant condition, that the subtraction term exponentially decays with the number of e -folds. As in the result for the canonical inflation, the regularized power spectrum tends to the "bare" power spectrum as the Universe expands during (and even after) inflation. This work justifies the use of the "bare" power spectrum in standard calculation in the most general context of slow-roll single-field inflation involving nonminimal coupling and varying speed of sound.

Removing ECG Artifact from the Surface EMG Signal Using Adaptive Subtraction Technique

Science.gov (United States)

Abbaspour, S; Fallah, A

2014-01-01

Background: The electrocardiogram artifact is a major contamination in the electromyogram signals when electromyogram signal is recorded from upper trunk muscles and because of that the contaminated electromyogram is not useful. Objective: Removing electrocardiogram contamination from electromyogram signals. Methods: In this paper, the clean electromyogram signal, electrocardiogram artifact and electrocardiogram signal were recorded from leg muscles, the pectoralis major muscle of the left side and V4, respectively. After the pre-processing, contaminated electromyogram signal is simulated with a combination of clean electromyogram and electrocardiogram artifact. Then, contaminated electromyogram is cleaned using adaptive subtraction method. This method contains some steps; (1) QRS detection, (2) formation of electrocardiogram template by averaging the electrocardiogram complexes, (3) using low pass filter to remove undesirable artifacts, (4) subtraction. Results: Performance of our method is evaluated using qualitative criteria, power spectrum density and coherence and quantitative criteria signal to noise ratio, relative error and cross correlation. The result of signal to noise ratio, relative error and cross correlation is equal to 10.493, 0.04 and %97 respectively. Finally, there is a comparison between proposed method and some existing methods. Conclusion: The result indicates that adaptive subtraction method is somewhat effective to remove electrocardiogram artifact from contaminated electromyogram signal and has an acceptable result. PMID:25505766

Clinical application of dynamic digital subtraction angiography in cerebrovascular ischemic diseases

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Hirata, Yoshifumi; Nonaka, Nobuhito; Matsukado, Yasuhiko; Takahashi, Mutsumasa

1987-09-01

Dynamic intravenous digital subtraction angiography (IV-DSA) was performed in 37 patients with cerebrovascular ischemic diseases. The time density curve of IV-DSA was analysed, and peak time, mean transit time and mode of transit time were obtained in each patient. On the basis of these values, cerebral perfusion was classified into low, normal and high perfusion patterns. Normal perfusion pattern was noted in 40% of patients with transient ischemic attack (TIA) and 7 % of patients with cerebral infarction. Low perfusion pattern was observed in 60 % of patients with TIA and 87 % of patients with cerebral infarction. High perfusion pattern was encountered only in 7 % of patients with cerebral infarction. In ischemic patients with moyamoya disease, extremely prolonged cerebral circulation time was evidenced by the presence of a flat or uphill type of the time density curve. This finding well correlated with decreased cerebral blood flow on single photon emission tomography. These findings suggest that the analysis of dynamic DSA is very important and useful in the clinical evaluation of patients with cerebrovascular ischemic diseases.

Intraarterial digital subtraction angiography applied to diagnosis of hepatocellular carcinoma

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Nishizawa, Sadahiko; Sano, Akira; Imanaka, Kazufumi; Sasai, Keisuke; Nagae, Toshiyuki; Mizutani, Masaru; Hatabu, Hiroto; Sadatou, Norihiro; Kuroda, Yasumasa

1985-12-01

This paper deals with diagnostic values of intraarterial digital subtraction angiography (IADSA) for evaluating hepatocellular carcinoma. The present series consists of 44 patients with hepatocellular carcinoma, who underwent IADSA combined with conventional hepatic angiography 67 times in total. The evaluated vessels by IADSA included 70 hepatic arteries and 36 portal veins. Comparative studies on the image quality of IADSA with conventional angiography were made in referring to the tumor stain for arteriograms and resolution of intrahepatic portal branches for portograms. Diagnostic superiority including equality of DSA image to conventional was noted in arteriograms: 72.7 % in the right lobe and 86 % in the left. Most deteriorated DSA images were caused by misregistration artifacts. IADSA portography revealed basically diagnostic values to demonstrate lobar, segmental or more peripheral branches in about 95 % of cases studied. DSA, characterized by high contrast resolution and real-time subtraction, offered important and effective informations for interventional angiography as well as resectability of the tumors, requiring less contrast medium.

Digital subtraction angiography in pediatric cerebrovascular occlusive disease

International Nuclear Information System (INIS)

Faerber, E.N.; Griska, L.A.B.; Swartz, J.D.; Capitanio, M.A.; Popky, G.L.

1984-01-01

While conventional angiography has been used to demonstrate cerebrovascular occlusive disease in the past, digital subtraction angiography (DSA) is capable of showing progressive vascular involvement with ease, simplicity, and extremely low morbidity, making it particularly well suited for children and outpatients either alone or coordinated with computed tomography. The authors discuss the usefulness and advantages of DSA as demonstrated in 7 infants and children with hemiplegia, 4 of whom had sickle-cell disease

Digital subtraction angiography of the thoracic aorta

International Nuclear Information System (INIS)

Grossman, L.B.; Buonocore, E.; Modic, M.T.; Meaney, T.F.

1984-01-01

Forty-three patients with acquired and congenital abnormalities of the thoracic aorta were studied using digital subtraction angiography (DSA) after an intravenous bolus injection of 40 ml of contrast material. Abnormalities studied included coarctation, pseudocoarctation, Marfan syndrome, cervical aorta, double aortic arch, aneurysm, dissection, and tumor. Twenty-four patients also had conventional angiography. DSA was accurate in 95% of cases; in the other 5%, involving patients with acute type I dissection, the coronary arteries could not be seen. The authors concluded that in 92% of their patients, DSA could have replaced the standard aortogram

Digital subtraction angiography of the thoracic aorta

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Grossman, L.B.; Buonocore, E.; Modic, M.T.; Meaney, T.F.

1984-02-01

Forty-three patients with acquired and congenital abnormalities of the thoracic aorta were studied using digital subtraction angiography (DSA) after an intravenous bolus injection of 40 ml of contrast material. Abnormalities studied included coarctation, pseudocoarctation, Marfan syndrome, cervical aorta, double aortic arch, aneurysm, dissection, and tumor. Twenty-four patients also had conventional angiography. DSA was accurate in 95% of cases; in the other 5%, involving patients with acute type I dissection, the coronary arteries could not be seen. The authors concluded that in 92% of their patients, DSA could have replaced the standard aortogram.

Real-time digital x-ray subtraction imaging

International Nuclear Information System (INIS)

Mistretta, C.A.; Kruger, R.A.; Houk, T.L.

1982-01-01

A method of producing visible difference images derived from an x-ray image of an anatomical subject is described. X-rays are directed through the subject, and the image is converted into television fields comprising trains of analog video signals. The analog signals are converted into digital signals, which are then integrated over a predetermined time corresponding to several television fields. Difference video signals are produced by performing a subtraction between the ongoing video signals and the corresponding integrated signals, and are converted into visible television difference images representing changes in the x-ray image

Clinical application of digital subtraction angiography (DSA)

International Nuclear Information System (INIS)

Morimoto, Tadashi; Kaku, Suiei; Morikawa, Eiji

1984-01-01

Intra-arterial digital subtraction angiography (IA-DSA) by the direct puncture of the carotid artery was described with special reference to its techniques, and cases were presented. This method was safe and painless and could be performed repeatedly. Cerebral angiographic images obtained by this method were either superior or fully compatible to the conventional cerebral angiography. It is therefore of great diagnostic value and can replace the conventional method. Furthermore, since the pretreatment is unnecessary and the time required is short, IA-DSA can be used as an adjuvant method for emergency diagnosis. (Namekawa, K)

Procedures for imaging of hemodialysis fistulas with particular reference to digital subtraction angiography (DSA)

International Nuclear Information System (INIS)

Neufang, K.F.R.; Erasmi-Koerber, H.; Wimmer, G.; Koeln Univ.

1983-01-01

All angiographic procedures established for imaging of hemodialysis fistulas, such as direct venous angiography, intravenous subtraction angiography and arteriography by direct puncture of the brachial artery of by Seldinger's transfemoral technique, can also be effected with digital image processing. Depending on the angiographic technique, the use of digital subtraction angiography has several advantages: lower doses and concentrations of the contrast agent, lower risk of complications (thrombosis of the fistula, vasospasm) and freedom from pain. In addition, there is a marked reduction of examination time and film cost. (orig.)

Evaluation of chronic periapical lesions by digital subtraction radiography by using Adobe Photoshop CS: a technical report.

Science.gov (United States)

Carvalho, Fabiola B; Gonçalves, Marcelo; Tanomaru-Filho, Mário

2007-04-01

The purpose of this study was to describe a new technique by using Adobe Photoshop CS (San Jose, CA) image-analysis software to evaluate the radiographic changes of chronic periapical lesions after root canal treatment by digital subtraction radiography. Thirteen upper anterior human teeth with pulp necrosis and radiographic image of chronic periapical lesion were endodontically treated and radiographed 0, 2, 4, and 6 months after root canal treatment by using a film holder. The radiographic films were automatically developed and digitized. The radiographic images taken 0, 2, 4, and 6 months after root canal therapy were submitted to digital subtraction in pairs (0 and 2 months, 2 and 4 months, and 4 and 6 months) choosing "image," "calculation," "subtract," and "new document" tools from Adobe Photoshop CS image-analysis software toolbar. The resulting images showed areas of periapical healing in all cases. According to this methodology, the healing or expansion of periapical lesions can be evaluated by means of digital subtraction radiography by using Adobe Photoshop CS software.

Increasing LIGO sensitivity by feedforward subtraction of auxiliary length control noise

International Nuclear Information System (INIS)

Meadors, Grant David; Riles, Keith; Kawabe, Keita

2014-01-01

LIGO, the Laser Interferometer Gravitational-wave Observatory, has been designed and constructed to measure gravitational wave strain via differential arm length. The LIGO 4 km Michelson arms with Fabry–Perot cavities have auxiliary length control servos for suppressing Michelson motion of the beam-splitter and arm cavity input mirrors, which degrades interferometer sensitivity. We demonstrate how a post facto pipeline improves a data sample from LIGO Science Run 6 with feedforward subtraction. Dividing data into 1024 s windows, we numerically fit filter functions representing the frequency-domain transfer functions from Michelson length channels into the gravitational-wave strain data channel for each window, then subtract the filtered Michelson channel noise (witness) from the strain channel (target). In this paper we describe the algorithm, assess achievable improvements in sensitivity to astrophysical sources, and consider relevance to future interferometry. (paper)

Use of digital subtraction angiography for renal transplant evaluation

International Nuclear Information System (INIS)

Fanucci, E.; Orlacchio, A.; Pocek, M.; Svegliati, F.

1986-01-01

Intravenous digital subtraction angiography (IVDSA) was used to evaluate 6 renal allograft recipients and 3 potential renal donors. In 4 potential renal donors and in 2 allograft recipients, angiographic data were confirmed by surgery. IVDSA is a safe, accurate, easily performed, outpatient procedure; in our opinion DSA should became the procedure of choice to study vascular anatomy in renal transplant evaluation

Evaluation of carotid vessel wall enhancement with image subtraction after gadobenate dimeglumine-enhanced MR angiography

International Nuclear Information System (INIS)

Sardanelli, Francesco; Di Leo, Giovanni; Aliprandi, Alberto; Flor, Nicola; Papini, Giacomo D.E.; Roccatagliata, Luca; Cotticelli, Biagio; Nano, Giovanni; Cornalba, Gianpaolo

2009-01-01

Objectives: This study was aimed at testing the value of image subtraction for evaluating carotid vessel wall enhancement in contrast-enhanced MR angiography (MRA). Materials and methods: IRB approval was obtained. The scans of 81 consecutive patients who underwent carotid MRA with 0.1 mmol/kg of gadobenate dimeglumine were reviewed. Axial carotid 3D T1-weighted fast low-angle shot sequence before and 3 min after contrast injection were acquired and subtracted (enhanced minus unenhanced). Vessel wall enhancement was assigned a four-point score using native or subtracted images from 0 (no enhancement) to 3 (strong enhancement). Stenosis degree was graded according to NASCET. Results: With native images, vessel wall enhancement was detected in 20/81 patients (25%) and in 20/161 carotids (12%), and scored 2.0 ± 0.6 (mean ± standard deviation); with subtracted images, in 21/81 (26%) and 22/161 (14%), and scored 2.5 ± 0.6, respectively (P < 0.001, Sign test). The overall stenosis degree distribution was: mild, 41/161 (25%); moderate, 77/161 (48%); severe, 43/161 (27%). Carotids with moderate stenosis showed vessel wall enhancement with a frequency (17/77, 22%) significantly higher than that observed in carotids with mild stenosis (1/41, 2%) (P = 0.005, Fisher exact test) and higher, even though with borderline significance (P = 0.078, Fisher exact test), than that observed in carotids with severe stenosis (4/43, 9%). Conclusion: Roughly a quarter of patients undergoing carotid MRA showed vessel wall enhancement. Image subtraction improved vessel wall enhancement conspicuity. Vessel wall enhancement seems to be an event relatively independent from the degree of stenosis. Further studies are warranted to define the relation between vessel wall enhancement and histopathology, inflammatory status, and instability.

Reduction of Musical Noise in Spectral Subtraction Method Using Subframe Phase Randomization

Energy Technology Data Exchange (ETDEWEB)

Seok, J.W.; Bae, K.S. [Kyungpook National University, Taegu (Korea)

1999-06-01

The Subframe phase randomization method is applied to the spectral subtraction method to reduce the musical noise in nonvoicing region after speech enhancement. The musical noise in the spectral subtraction method is the result of the narrowband tonal components that appearing somewhat periodically in the spectrogram of unvoiced and silence regions. Thus each synthesis frame in nonvoicing region is divided into several subframes to broaden the narrowband spectrum, and then phases of silence and unvoiced regions are randomized to eliminate the tonal components in the spectrum while keeping the shape of the amplitude spectrum. Performance assessments based on visual inspection of spectrogram, objective measure, and informal subjective listening tests demonstrate the superiority of the proposed algorithm. (author). 7 refs., 5 figs.

Electron paramagnetic resonance in myoglobin single crystals doped with Cu(II) : conformational changes

International Nuclear Information System (INIS)

Nascimento, O.R.

1976-03-01

Single crystals of sperm whale met-Myoglobin were doped with Cu (II) by immersion in a saturaded solution of NH 3 (SO 4 ) containing diluted Cu (SO 4 ).Two isotropic EPR spectra with different parameters and three anisotropic EPR spectra corresponding to three distinct types of Cu(II) : Mb complexes were identified. A fitting of the angular variation of the EPR spectrum of one of the complexes named here Cu(II)A : Mb was done using a spin Hamiltonian with axial symmetry calculated up to second order which gave the EPR hyperfine parameters.A study of the thermal variation of the complex Cu (II)A : Mb EPR spectrum in the temperature range of 25 0 C to 55 0 C allowed an identification of a conformational variation of the molecule the spectrum evolved from the anisotropic to isotropic spectrum with different parameters. A model of the Cu(II)A : Mb complex is proposed to explain the conformational change of the molecule by means of EPR spectra before and after thermal treatment. The isotropic spectrum obtained with the crystal at 55 0 C presents the EPR parameters very similar to the same parameters obtained with the Cu (II) : Mb complex in aqueous solution at 77 0 K, whereas the isotropic spectra parameters obtained with the dried crystal are quite different. It was possible to identify two different tertiary structures of the myoglobin molecule : one corresponding to the molecule in the crystal at 55 0 C and other to the dry crystal. A slight difference in the crystalline and solution structure of the myoglobin mollecule is observed. (Author) [pt

Fabrication of lithium ceramic pellets, rings and single crystals for irradiation in BEATRIX-II

International Nuclear Information System (INIS)

Slagle, O.D.; Noda, K.; Takahashi, T.

1989-04-01

BEATRIX-II is an IEA sponsored experiment of lithium ceramic solid breeder materials in the FFTF/MOTA. Li 2 O solid pellets and annular ring specimens were fabricated for in-situ tritium release tests. In addition, a series of single crystal and polycrystalline lithium ceramic samples were fabricated to determine the irradiation behavior and beryllium compatibility. 6 refs., 10 figs., 4 tabs

Motion compensation in digital subtraction angiography using graphics hardware.

Science.gov (United States)

Deuerling-Zheng, Yu; Lell, Michael; Galant, Adam; Hornegger, Joachim

2006-07-01

An inherent disadvantage of digital subtraction angiography (DSA) is its sensitivity to patient motion which causes artifacts in the subtraction images. These artifacts could often reduce the diagnostic value of this technique. Automated, fast and accurate motion compensation is therefore required. To cope with this requirement, we first examine a method explicitly designed to detect local motions in DSA. Then, we implement a motion compensation algorithm by means of block matching on modern graphics hardware. Both methods search for maximal local similarity by evaluating a histogram-based measure. In this context, we are the first who have mapped an optimizing search strategy on graphics hardware while paralleling block matching. Moreover, we provide an innovative method for creating histograms on graphics hardware with vertex texturing and frame buffer blending. It turns out that both methods can effectively correct the artifacts in most case, as the hardware implementation of block matching performs much faster: the displacements of two 1024 x 1024 images can be calculated at 3 frames/s with integer precision or 2 frames/s with sub-pixel precision. Preliminary clinical evaluation indicates that the computation with integer precision could already be sufficient.

Notes on some experiments on the application of subtractive compensation to USGS seismic magnetic tape recording and playback systems

Science.gov (United States)

Eaton, Jerry P.

1975-01-01

The purpose of these experiments is to lay the groundwork for the implementation of subtractive compensation of the USGS seismic network tape playbacks utilizing the Develco model 6203 discriminators at a x1 playback speed. Although the Develco discriminators were designed for this application and a matching Develco compensation discriminator was purchased, effective use of this system for subtractive compensation has been blocked by the inadequate (frequency dependent) matching of the phase of the compensation signal to that of the data signal at the point compensation is carried out in the data discriminators. John Van Schaack has ameliorated the phase mismatch problem by an empirical alteration of the compensation discriminator input bandpass filter. We have selected a set (of eight) Develco discriminators and adjusted their compensation signal input levels to minimize spurious signals (noise) originating from tape speed irregularities. The sensitivity of the data discriminators was adjusted so that deviations of +125 Hz and -125 Hz produced output signals of +2.00 volts and -2.00 volts, respectively. The eight data discriminators are driven by a multiplex signal on a single tape track (subcarriers 680, 1020, 1360, 1700, 2040, 2380, 2720, and 3060 Hz). The Develco-supplied compensation discriminator requires an unmodulated 3125 Hz signal on a separate tape track.

Value of Single-Dose Contrast-Enhanced Magnetic Resonance Angiography Versus Intraarterial Digital Subtraction Angiography in Therapy Indications in Abdominal and Iliac Arteries

International Nuclear Information System (INIS)

Schaefer, Philipp J.; Schaefer, Fritz K. W.; Mueller-Huelsbeck, Stefan; Both, Markus; Heller, Martin; Jahnke, Thomas

2007-01-01

The objective of the study was to prove the value of single-dose contrast-enhanced magnetic resonance angiography [three-dimensional (3D) ceMRA] in abdominal and iliac arteries versus the reference standard intra-arterial digital subtraction angiography (i.a.DSA) when indicating a therapy. Patients suspected of having abdominal or iliac artery stenosis were included in this study. A positive vote of the local Ethics Committee was given. After written informed consent was obtained, 37 patients were enrolled, of which 34 were available for image evaluation. Both 3D ceMRA and i.a. DSA were performed for each patient. The dosage for 3D ceMRA was 0.1 mmol/kg body weight in a 1.5-T scanner with a phased-array coil. The parameters of the 3D-FLASH sequence were as follows: TR/TE 4.6/1.8 ms, effective thickness 3.5 mm, matrix 512 x 200, flip angle 30 o , field of view 420 mm, TA 23 s, coronal scan orientation. Totally, 476 vessel segments were evaluated for stenosis degree by two radiologists in a consensus fashion in a blinded read. For each patient, a therapy was proposed, if clinically indicated. Sensitivity, specificity, positive and negative predictive values, and accuracy for stenoses ≥50% were 68%, 92%, 44%, 97%, and 90%, respectively. In 13/34 patients, a discrepancy was found concerning therapy decisions based on MRA findings versus therapy decisions based on the reference standard DSA. The results showed that the used MRA imaging technique of abdominal and iliac arteries is not competitive to i.a. DSA, with a high rate of misinterpretation of the MRAs resulting in incorrect therapies

A novel approach to background subtraction in contrast-enhanced dual-energy digital mammography with commercially available mammography devices: Noise minimization

International Nuclear Information System (INIS)

Contillo, Adriano; Di Domenico, Giovanni; Cardarelli, Paolo; Gambaccini, Mauro; Taibi, Angelo

2016-01-01

Purpose: Dual-energy image subtraction represents a useful tool to improve the detectability of small lesions, especially in dense breasts. A feature it shares with all x-ray imaging techniques is the appearance of fluctuations in the texture of the background, which can obscure the visibility of interesting details. The aim of the work is to investigate the main noise sources, in order to create a better performing subtraction mechanism. In particular, the structural noise cancellation was achieved by means of a suitable extension of the dual-energy algorithm. Methods: The effect of the cancellation procedure was tested on an analytical simulation of a target with varying structural composition. Subsequently, the subtraction algorithm was also applied to a set of actual radiographs of a breast phantom exhibiting a nonuniform background pattern. The background power spectra of the outcomes were computed and compared to the ones obtained from a standard subtraction algorithm. Results: The comparison between the standard and the proposed cancellations showed an overall suppression of the magnitudes of the spectra, as well as a flattening of the frequency dependence of the structural component of the noise. Conclusions: The proposed subtraction procedure provides an effective cancellation of the residual background fluctuations. When combined with the polychromatic correction already described in a companion publication, it results in a high performing dual-energy subtraction scheme for commercial mammography units.

A novel approach to background subtraction in contrast-enhanced dual-energy digital mammography with commercially available mammography devices: Noise minimization

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Contillo, Adriano, E-mail: contillo@fe.infn.it; Di Domenico, Giovanni; Cardarelli, Paolo; Gambaccini, Mauro; Taibi, Angelo [Dipartimento di Fisica e Scienze della Terra, Università degli Studi di Ferrara, Via Saragat 1, I-44122 Ferrara (Italy)

2016-06-15

Purpose: Dual-energy image subtraction represents a useful tool to improve the detectability of small lesions, especially in dense breasts. A feature it shares with all x-ray imaging techniques is the appearance of fluctuations in the texture of the background, which can obscure the visibility of interesting details. The aim of the work is to investigate the main noise sources, in order to create a better performing subtraction mechanism. In particular, the structural noise cancellation was achieved by means of a suitable extension of the dual-energy algorithm. Methods: The effect of the cancellation procedure was tested on an analytical simulation of a target with varying structural composition. Subsequently, the subtraction algorithm was also applied to a set of actual radiographs of a breast phantom exhibiting a nonuniform background pattern. The background power spectra of the outcomes were computed and compared to the ones obtained from a standard subtraction algorithm. Results: The comparison between the standard and the proposed cancellations showed an overall suppression of the magnitudes of the spectra, as well as a flattening of the frequency dependence of the structural component of the noise. Conclusions: The proposed subtraction procedure provides an effective cancellation of the residual background fluctuations. When combined with the polychromatic correction already described in a companion publication, it results in a high performing dual-energy subtraction scheme for commercial mammography units.

DESIGN STUDY: INTEGER SUBTRACTION OPERATION TEACHING LEARNING USING MULTIMEDIA IN PRIMARY SCHOOL

Directory of Open Access Journals (Sweden)

Rendi Muhammad Aris

2016-12-01

Full Text Available This study aims to develop a learning trajectory to help students understand concept of subtraction of integers using multimedia in the fourth grade. This study is thematic integrative learning in Curriculum 2013 PMRI based. The method used is design research consists of three stages; preparing for the experiment, design experiment, retrospective analysis. The studied was conducted on 20 students of grade four SDN 1 Muara Batun, OKI. The activities of students in this study consisted of six learning trajectories. The first activity asks the students to classify heroism and non-heroism acts, summarize, and classify integers and non-integer. The second activity asks the students to answer the questions in the film given. The third activity asks students to count the remaining gravel in the film. The fourth activity asks students to count remaining spent money in the film. The fifth activity invites students to play rubber seeds in the bag. The last activity asks students to answer the questions in the student worksheet. The media used along the learning activities are a ruler, rubber seed, student worksheet, money, gravel, and film. The results indicate that the learning trajectory using multimedia help students understand the concept of integer subtraction integer. Keywords: Subtraction Integer, PMRI, Multimedia DOI: http://dx.doi.org/10.22342/jme.8.1.3233.95-102

Intravenous digital subtraction angiography investigation of reversible cerebral ischemia

International Nuclear Information System (INIS)

Pistolesi, G.F.; Maso, R.; Filosto, L.; Piovan, E.; Morgante, D.; Taddei, G.; Tonegutti, M.; Portuese, A.

1986-01-01

The brachio-cephalic, carotid, vertebral and intra-cranial vessels of 497 patients presenting reversible ischemic attacks (R.I.A) were evaluated with venous digital subtraction angiography (V.D.S.A.). Alterations of the vascular wall were observed in 289/497 (58.2%) patients, of whom 60% presented multiple locations (539 lesions): obstruction (12%), stenosis >50% (29%), stenosis 50%. The incidence of vascular lesions was higher (p [fr

Segmentation of Moving Object Using Background Subtraction Method in Complex Environments

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S. Kumar

2016-06-01

Full Text Available Background subtraction is an extensively used approach to localize the moving object in a video sequence. However, detecting an object under the spatiotemporal behavior of background such as rippling of water, moving curtain and illumination change or low resolution is not a straightforward task. To deal with the above-mentioned problem, we address a background maintenance scheme based on the updating of background pixels by estimating the current spatial variance along the temporal line. The work is focused to immune the variation of local motion in the background. Finally, the most suitable label assignment to the motion field is estimated and optimized by using iterated conditional mode (ICM under a Markovian framework. Performance evaluation and comparisons with the other well-known background subtraction methods show that the proposed method is unaffected by the problem of aperture distortion, ghost image, and high frequency noise.

[Myocardial perfusion imaging by digital subtraction angiography].

Science.gov (United States)

Kadowaki, H; Ishikawa, K; Ogai, T; Katori, R

1986-03-01

Several methods of digital subtraction angiography (DSA) were compared to determine which could better visualize regional myocardial perfusion using coronary angiography in seven patients with myocardial infarction, two with angina pectoris and five with normal coronary arteries. Satisfactory DSA was judged to be achieved if the shape of the heart on the mask film was identical to that on the live film and if both films were exactly superimposed. To obtain an identical mask film in the shape of each live film, both films were selected from the following three phases of the cardiac cycle; at the R wave of the electrocardiogram, 100 msec before the R wave, and 200 msec before the R wave. The last two were superior for obtaining mask and live films which were similar in shape, because the cardiac motion in these phases was relatively small. Using these mask and live films, DSA was performed either with the continuous image mode (CI mode) or the time interval difference mode (TID mode). The overall perfusion of contrast medium through the artery to the vein was adequately visualized using the CI mode. Passage of contrast medium through the artery, capillary and vein was visualized at each phase using TID mode. Subtracted images were displayed and photographed, and the density of the contrast medium was adequate to display contour lines as in a relief map. Using this DSA, it was found that regional perfusion of the contrast medium was not always uniform in normal subjects, depending on the typography of the coronary artery.(ABSTRACT TRUNCATED AT 250 WORDS)

Using a digital signal processor as a data stream controller for digital subtraction angiography

International Nuclear Information System (INIS)

Meng, J.D.; Katz, J.E.

1991-10-01

High speed, flexibility, and good arithmetic abilities make digital signal processors (DSP) a good choice as input/output controllers for real time applications. The DSP can be made to pre-process data in real time to reduce data volume, to open early windows on what is being acquired and to implement local servo loops. We present an example of a DSP as an input/output controller for a digital subtraction angiographic imaging system. The DSP pre-processes the raw data, reducing data volume by a factor of two, and is potentially capable of producing real-time subtracted images for immediate display

Non-perturbative subtractions in the heavy quark effective field theory

International Nuclear Information System (INIS)

Maiani, L.; Martinelli, G.; Sachrajda, C.T.

1992-01-01

We demonstrate the presence of ultraviolet power divergences in the O(1/m h ) corrections to matrix elements of hadronic operators containing a heavy quark field (where m h is the mass of the heavy quark). These power divergences must be subtracted non-perturbatively. The implications for lattice computations are discussed in detail. (orig.)

Digital subtraction angiography in the evaluation of chemodectomas

International Nuclear Information System (INIS)

Vlahos, L.; Papathanasiou, M.; Gouliamos, A.; Dimakakos, P.; Papavassiliou, C.

1988-01-01

During the last 2 years eleven patients with surgically confirmed chemodectomas have been investigated by means of digital subtraction angiography (DSA). Seven patients underwent i.v. DSA, which revealed eight carotid body tumours, and in the remaining four with jugulotympanic chemodectomas intra-arterial (i.a.) DSA was performed. We found i.v. DSA an easy and satisfactory method for the investigation of carotid body tumours but when glomus intravagale, tympanicum or jugulare is suspected an i.a. selective injection is required. (orig.) [de

Digital subtraction angiography in the evaluation of chemodectomas

Energy Technology Data Exchange (ETDEWEB)

Vlahos, L.; Papathanasiou, M.; Gouliamos, A.; Dimakakos, P.; Papavassiliou, C.

1988-05-01

During the last 2 years eleven patients with surgically confirmed chemodectomas have been investigated by means of digital subtraction angiography (DSA). Seven patients underwent i.v. DSA, which revealed eight carotid body tumours, and in the remaining four with jugulotympanic chemodectomas intra-arterial (i.a.) DSA was performed. We found i.v. DSA an easy and satisfactory method for the investigation of carotid body tumours but when glomus intravagale, tympanicum or jugulare is suspected an i.a. selective injection is required.

Construction and partial sequencing of a subtractive library in Calcutta 4 (Musa AA in early stage of infection with Mycosphaerella fijiensis Morelet

Directory of Open Access Journals (Sweden)

Milady Mendoza-Rodríguez

2006-10-01

Full Text Available The study of genes involved in plant defense response against pathogen attack, is one of most important steps leading to the elucidation of disease resistance molecular mechanisms. The generation of subtracted deoxyribonucleic acid libraries (cDNA, by means of suppression subtractive hybridization technique (SSH, has been used for this purpose. A subtractive hybridization was made between a cDNA population obtained from ‘Calcutta 4’ inoculated leaves with M. fijiensis (CCIBP-Pf83 and a mixture of cDNA from ‘Calcutta 4’ non inoculated leaves and mycelium. Leaves samples were taken at 6, 10 and 12 days after inoculation. The subtracted library was obtained by cloning and transformation of subtracted products and as a result, 600 recombinants clones were obtained. Sequence analysis of sixty nine clones, revealed redundancy of the expressed sequence tags and most of them showed no homology with reported sequences at databases and only 13 % had a high homology with metalothioneins. The results constitute a step in advance in the molecular study of Musa-Mycosphaerella fijiensis interaction. Key words: Banana-Mycosphaerella fijiensis interaction, BlackSigatoka, Musa spp., suppression subtractive hybridization

Digital subtraction angiography (DSA) of the heart and coronary arteries

International Nuclear Information System (INIS)

Struyven, J.J.; Delcour, C.; Brion, J.P.; Vandenbosch, G.; Claessens, J.

1986-01-01

Digital subtraction angiography has potential advantages over conventional radiography. The removal of background structures makes possible to visualize chambers of the heart, great vessels and coronary arteries with a lower iodine signal than with conventional cineangiography. Digital data used for imaging can been manipulated for assessment and quantitation of the ventricular fonction and the coronary circulation

Pulmonary arteriography by digital subtraction angiographic method in cyanotic heart disease with pulmonary stenosis or pulmonary atresia

International Nuclear Information System (INIS)

Kobayashi, Junjiro; Hirose, Hajime; Nakano, Susumu

1985-01-01

Pulmonary arteriography was performed by digital subtraction angiographic (DSA) method in 10 patients with cyanotic heart disease associated with pulmonary stenosis or pulmonary atresia. Ten patients consisted of five patients with tetralogy of Fallot, three with single ventricle and pulmonary stenosis, and two with pseudotruncus arteriosus. Hepato-clavicular position was taken in four patients. Pulmonary artery and its main branches were opacified and recognized clearly, and their diameter could be measured accurately with a small amount of contrast medium. There was a good correlation between the diameter of pulmonary artery measured by DSA and that measured by conventional pulmonary arteriography. DSA is a useful method for evaluating the size and the stenosis of pulmonary artery especially in small cyanotic infants. (author)

K-edge subtraction synchrotron X-ray imaging in bio-medical research.

Science.gov (United States)

Thomlinson, W; Elleaume, H; Porra, L; Suortti, P

2018-05-01

High contrast in X-ray medical imaging, while maintaining acceptable radiation dose levels to the patient, has long been a goal. One of the most promising methods is that of K-edge subtraction imaging. This technique, first advanced as long ago as 1953 by B. Jacobson, uses the large difference in the absorption coefficient of elements at energies above and below the K-edge. Two images, one taken above the edge and one below the edge, are subtracted leaving, ideally, only the image of the distribution of the target element. This paper reviews the development of the KES techniques and technology as applied to bio-medical imaging from the early low-power tube sources of X-rays to the latest high-power synchrotron sources. Applications to coronary angiography, functional lung imaging and bone growth are highlighted. A vision of possible imaging with new compact sources is presented. Copyright © 2018 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

Predictive value of digital subtraction angiography in patients with tuberculous meningitis

International Nuclear Information System (INIS)

Rojas-Echeverri, L.A.; Soto-Hernandez, J.L.; Garza, S.; Martinez-Zubieta, R.; Miranda, L.I.; Garcia-Ramos, G.; Zenteno, M.

1996-01-01

Digital subtraction angiography (DSA) was performed in 24 adults with tuberculous meningitis (TBM) and results were correlated with 24 admission and 16 follow-up CT examinations. 19 MRI studies and clinical outcome at a mean follow-up of 44 weeks. DSA was abnormal in 11 patients. Abnormal DSA was associated with advenced clinical stages of the Medical Research Council classification, admission CT with hydrocephalus or gyral cortical enhancement. MRI disclosed brain infarcts not seen on initial CT in 8 cases. Of seven patients who died, 4 had abnormal and 3 normal DSA. Among patients who survived, those with normal DSA had a better functional outcome by Karnofsky scores. During follow-up infarcts were evident in 16 patients. Abnormal DSA in relation to brain infarcts had a sensitivity of 0.56, specificity 0.75, positive predictive value 0.82 and negative predictive value 0.46. A single arteriogram does not predict the outcome in patients with TBM and its value is limited in the assessment of vascular complications of TBM. Angiography in TBM is justified only in specific clinical trials to assess new therapeutic modalities against infarcts. (orig.)

Zinc(II) and the single-stranded DNA binding protein of bacteriophage T4

International Nuclear Information System (INIS)

Gauss, P.; Krassa, K.B.; McPheeters, D.S.; Nelson, M.A.; Gold, L.

1987-01-01

The DNA binding domain of the gene 32 protein of the bacteriophage T4 contains a single zinc-finger sequence. The gene 32 protein is an extensively studied member of a class of proteins that bind relatively nonspecifically to single-stranded DNA. The authors have sequenced and characterized mutations in gene 32 whose defective proteins are activated by increasing the Zn(II) concentration in the growth medium. The results identify a role for the gene 32 protein in activation of T4 late transcription. Several eukaryotic proteins with zinc fingers participate in activation of transcription, and the gene 32 protein of T4 should provide a simple, well-characterized system in which genetics can be utilized to study the role of a zinc finger in nucleic acid binding and gene expression

Evaluation of left ventricular function using digital subtraction ventriculography

International Nuclear Information System (INIS)

Yiannikas, J.; Detrano, R.

1986-01-01

Digital subtraction ventriculography following injections of contrast via peripheral veins provides excellent images to assess left ventricular function. The images are essentially identical to those following DCV, but allow more uniform mixing of contrast in the left ventricular chamber. Furthermore, few, if any, cardiac arrhythmias occur, hence obviating difficulties that arise from DCV. The spatial resolution of the method is such that regional wall motion assessment of ventricular function is more accurate than that of other noninvasive imaging methods. The use of video-densitometry allows accurate assessment of left ventricular function even when the left ventricular cavity is nonsymmetrically deformed and aneurysmal. In the setting of the cardiac catheterization laboratory, digital ventriculography may provide a safer means of assessing left ventricular function when critical coronary or myocardial disease is present and allows multiple assessments of ventricular function during the same study. Although excellent correlations with standard ventriculography have been noted by all workers, significant discrepancies still exist in individual patients, particularly in the calculations of end diastolic volumes. In the authors experience and in those of most workers, the largest discrepancies existed in patients in whom suboptimal studies are included for analysis. The most frequent reason for the occasional suboptimal study as with all digital subtraction work is the misregistration that results from motion

Brain MR post-gadolinium contrast in multiple sclerosis: the role of magnetization transfer and image subtraction in detecting more enhancing lesions

Energy Technology Data Exchange (ETDEWEB)

Gavra, M.M.; Gouliamos, A.D.; Vlahos, L.J. [Department of Radiology, ' ' Aretaieion' ' Hospital,University of Athens Medical School, Athens (Greece); Voumvourakis, C.; Sfagos, C. [Department of Neurology, ' ' Eginiteion' ' Hospital, University of Athens Medical School, Athens (Greece)

2004-03-01

Our purpose was to evaluate the role of magnetization transfer and image subtraction in detecting more enhancing lesions in brain MR imaging of patients with multiple sclerosis (MS). Thirty-one MS patients underwent MR imaging of the brain with T1-weighted spin echo sequences without and with magnetization transfer (MT) using a 1.5 T imager. Both sequences were acquired before and after intravenous injection of a paramagnetic contrast agent. Subtraction images in T1-weighted sequences were obtained by subtracting the pre-contrast images from the post-contrast ones. A significant difference was found between the numbers of enhanced areas in post-gadolinium T1-weighted images without and with MT (p=0.020). The post-gadolinium T1-weighted images with MT allowed the detection of an increased (13) number of enhancing lesions compared with post-gadolinium T1-weighted images without MT. A significant difference was also found between the numbers of enhanced areas in post-gadolinium T1-weighted images without MT and subtraction images without MT (p=0.020). The subtraction images without MT allowed the detection of an increased (10) number of enhancing lesions compared with post-gadolinium T1-weighted images without MT. Magnetization transfer contrast and subtraction techniques appear to be the simplest and least time-consuming applications to improve the conspicuity and detection of contrast-enhancing lesions in patients with MS. (orig.)

Brain MR post-gadolinium contrast in multiple sclerosis: the role of magnetization transfer and image subtraction in detecting more enhancing lesions

International Nuclear Information System (INIS)

Gavra, M.M.; Gouliamos, A.D.; Vlahos, L.J.; Voumvourakis, C.; Sfagos, C.

2004-01-01

Our purpose was to evaluate the role of magnetization transfer and image subtraction in detecting more enhancing lesions in brain MR imaging of patients with multiple sclerosis (MS). Thirty-one MS patients underwent MR imaging of the brain with T1-weighted spin echo sequences without and with magnetization transfer (MT) using a 1.5 T imager. Both sequences were acquired before and after intravenous injection of a paramagnetic contrast agent. Subtraction images in T1-weighted sequences were obtained by subtracting the pre-contrast images from the post-contrast ones. A significant difference was found between the numbers of enhanced areas in post-gadolinium T1-weighted images without and with MT (p=0.020). The post-gadolinium T1-weighted images with MT allowed the detection of an increased (13) number of enhancing lesions compared with post-gadolinium T1-weighted images without MT. A significant difference was also found between the numbers of enhanced areas in post-gadolinium T1-weighted images without MT and subtraction images without MT (p=0.020). The subtraction images without MT allowed the detection of an increased (10) number of enhancing lesions compared with post-gadolinium T1-weighted images without MT. Magnetization transfer contrast and subtraction techniques appear to be the simplest and least time-consuming applications to improve the conspicuity and detection of contrast-enhancing lesions in patients with MS. (orig.)

Performance of computed tomography for contrast agent concentration measurements with monochromatic x-ray beams: comparison of K-edge versus temporal subtraction

International Nuclear Information System (INIS)

Elleaume, H.; Charvet, A.M.; Corde, S.; Esteve, F.; Le Bas, J.F.

2002-01-01

We investigated the performance of monochromatic computed tomography for the quantification of contrast agent concentrations. Two subtraction methods (K-edge subtraction and temporal subtraction) were evaluated and compared theoretically and experimentally in terms of detection limit, precision and accuracy. Measurements were performed using synchrotron x-rays with Lucite phantoms (10 cm and 17.5 cm in diameter) containing iodine or gadolinium solutions ranging from 50 μg ml -1 to 5 mg ml -1 . The experiments were carried out using monochromators developed at the European Synchrotron Radiation Facility (ESRF) medical beamline. The phantoms were imaged either above and below the contrast agent K-edge, or before and after the addition of the contrast agent. Both methods gave comparable performance for phantoms less than 10 cm in diameter. For large phantoms, equivalent to a human head, the temporal subtraction is more suitable for detecting elements such as iodine, keeping a reasonable x-ray dose delivered to the phantom. A good agreement was obtained between analytical calculations, simulations and measurements. The beam harmonic content was taken into account in the simulations. It explains the performance degradation with high contrast agent concentrations. The temporal subtraction technique has the advantage of energy tunability and is well suited for imaging elements, such as iodine or gadolinium, in highly absorbing samples. For technical reasons, the K-edge method is preferable when the imaged organ is moving since the two measurements can be performed simultaneously, which is mandatory for obtaining a good subtraction. (author)

Quantitative analysis of alveolar bone change following implant placement using intraoral radiographic subtraction

International Nuclear Information System (INIS)

Kimura, Hiroyuki; Kanda, Shigenobu; Tanaka, Takemasa

2002-01-01

The purpose of this study was to develop a procedure for quantitative analysis using intraoral radiographs of alveolar bone after placement of dental implants and to consider the validity of the method. We evaluated the ten patients (2 males and 8 females, average age: 48.4 years-old), who were treated with dental implant operation in the site of mandibular molar region, since October of 1999 until September of 2000 in Kimura Dental Clinic (Kumamoto, Japan). We evaluated the intraoral radiographs taken pre- and post- operatively and at follow-up examination. To detect alveolar bone change on radiograph, we adopted the digital subtraction method. Although the radiographs were taken under an ordinary technique with cone indicator, we did not apply the standardized technique with fixing material customized for each patient. Therefore, we used geometric correction and density compensation before subtraction. We assessed the basic statistical values (mean, variance, kurtosis and skewness) of the region of interest (ROI) of the subtracted images. Also, we noted PPD (probing pocket depth) and BOP (bleeding on probing) at each site as indicators of clinical findings and all implanted sites were classified according to the PPD or BOP, i.e. PPD increased group ''PPD (+)'' and PPD stable group ''PPD (-)'', likewise BOP positive group ''BOP (+)'' and negative group ''BOP (-)''. We considered the statistical values of ROI in each group and compared these findings. Mean and variance values of PPD (+) were higher than those of PPD (-) and there was a significant difference in mean value (p=0.031). Similarly, mean and variance values of BOP (+) were statistically higher than those of BOP (-) (p=0.041 and p=0.0087, respectively). Concerning kurtosis and skewness, there was no difference between PPD (+) and PPD (-), or between BOP (+) and BOP (-). Using our method, the radiographs taken for follow-up examination could be assessed quantitatively. It is suggested that geometric

Analysis of luminosity distributions of strong lensing galaxies: subtraction of diffuse lensed signal

Science.gov (United States)

Biernaux, J.; Magain, P.; Hauret, C.

2017-08-01

Context. Strong gravitational lensing gives access to the total mass distribution of galaxies. It can unveil a great deal of information about the lenses' dark matter content when combined with the study of the lenses' light profile. However, gravitational lensing galaxies, by definition, appear surrounded by lensed signal, both point-like and diffuse, that is irrelevant to the lens flux. Therefore, the observer is most often restricted to studying the innermost portions of the galaxy, where classical fitting methods show some instabilities. Aims: We aim at subtracting that lensed signal and at characterising some lenses' light profile by computing their shape parameters (half-light radius, ellipticity, and position angle). Our objective is to evaluate the total integrated flux in an aperture the size of the Einstein ring in order to obtain a robust estimate of the quantity of ordinary (luminous) matter in each system. Methods: We are expanding the work we started in a previous paper that consisted in subtracting point-like lensed images and in independently measuring each shape parameter. We improve it by designing a subtraction of the diffuse lensed signal, based only on one simple hypothesis of symmetry. We apply it to the cases where it proves to be necessary. This extra step improves our study of the shape parameters and we refine it even more by upgrading our half-light radius measurement method. We also calculate the impact of our specific image processing on the error bars. Results: The diffuse lensed signal subtraction makes it possible to study a larger portion of relevant galactic flux, as the radius of the fitting region increases by on average 17%. We retrieve new half-light radii values that are on average 11% smaller than in our previous work, although the uncertainties overlap in most cases. This shows that not taking the diffuse lensed signal into account may lead to a significant overestimate of the half-light radius. We are also able to measure

Geometrical accuracy of metallic objects produced with additive or subtractive manufacturing: A comparative in vitro study.

Science.gov (United States)

Braian, Michael; Jönsson, David; Kevci, Mir; Wennerberg, Ann

2018-04-06

To evaluate the accuracy and precision of objects produced by additive manufacturing systems (AM) for use in dentistry and to compare with subtractive manufacturing systems (SM). Ten specimens of two geometrical objects were produced by five different AM machines and one SM machine. Object A mimics an inlay-shaped object, while object B imitates a four-unit bridge model. All the objects were sorted into different measurement dimensions (x, y, z), linear distances, angles and corner radius. None of the additive manufacturing or subtractive manufacturing groups presented a perfect match to the CAD file with regard to all parameters included in the present study. Considering linear measurements, the precision for subtractive manufacturing group was consistent in all axes for object A, presenting results of additive manufacturing groups had consistent precision in the x-axis and y-axis but not in the z-axis. With regard to corner radius measurements, the SM group had the best overall accuracy and precision for both objects A and B when compared to the AM groups. Within the limitations of this in vitro study, the conclusion can be made that subtractive manufacturing presented overall precision on all measurements below 0.050mm. The AM machines also presented fairly good precision, additive techniques are now being implemented. Thus all these production techniques need to be tested, compared and validated. Copyright © 2018 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved.

The potential for neurovascular intravenous angiography using K-edge digital subtraction angiography

International Nuclear Information System (INIS)

Schueltke, E.; Fiedler, S.; Kelly, M.; Griebel, R.; Juurlink, B.; LeDuc, G.; Esteve, F.; Le Bas, J.-F.; Renier, M.; Nemoz, C.; Meguro, K.

2005-01-01

Background: Catheterization of small-caliber blood vessels in the central nervous system can be extremely challenging. Alternatively, intravenous (i.v.) administration of contrast agent is minimally invasive and therefore carries a much lower risk for the patient. With conventional X-ray equipment, volumes of contrast agent that could be safely administered to the patient do not allow acquisition of high-quality images after i.v. injection, because the contrast bolus is extremely diluted by passage through the heart. However, synchrotron-based digital K-edge subtraction angiography does allow acquisition of high-quality images after i.v. administration of relatively small doses of contrast agent. Materials and methods: Eight adult male New Zealand rabbits were used for our experiments. Animals were submitted to both angiography with conventional X-ray equipment and synchrotron-based digital subtraction angiography. Results: With conventional X-ray equipment, no contrast was seen in either cerebral or spinal blood vessels after i.v. injection of iodinated contrast agent. However, using K-edge digital subtraction angiography, as little as 1 ml iodinated contrast agent, when administered as i.v. bolus, yielded images of small-caliber blood vessels in the central nervous system (both brain and spinal cord). Conclusions: If it would be possible to image blood vessels of the same diameter in the central nervous system of human patients, the synchrotron-based technique could yield high-quality images at a significantly lower risk for the patient than conventional X-ray imaging. Images could be acquired where catheterization of feeding blood vessels has proven impossible

The value of subtraction MRI in detection of amyloid-related imaging abnormalities with oedema or effusion in Alzheimer's patients: An interobserver study.

Science.gov (United States)

Martens, Roland M; Bechten, Arianne; Ingala, Silvia; van Schijndel, Ronald A; Machado, Vania B; de Jong, Marcus C; Sanchez, Esther; Purcell, Derk; Arrighi, Michael H; Brashear, Robert H; Wattjes, Mike P; Barkhof, Frederik

2018-03-01

Immunotherapeutic treatments targeting amyloid-β plaques in Alzheimer's disease (AD) are associated with the presence of amyloid-related imaging abnormalities with oedema or effusion (ARIA-E), whose detection and classification is crucial to evaluate subjects enrolled in clinical trials. To investigate the applicability of subtraction MRI in the ARIA-E detection using an established ARIA-E-rating scale. We included 75 AD patients receiving bapineuzumab treatment, including 29 ARIA-E cases. Five neuroradiologists rated their brain MRI-scans with and without subtraction images. The accuracy of evaluating the presence of ARIA-E, intraclass correlation coefficient (ICC) and specific agreement was calculated. Subtraction resulted in higher sensitivity (0.966) and lower specificity (0.970) than native images (0.959, 0.991, respectively). Individual rater detection was excellent. ICC scores ranged from excellent to good, except for gyral swelling (moderate). Excellent negative and good positive specific agreement among all ARIA-E imaging features was reported in both groups. Combining sulcal hyperintensity and gyral swelling significantly increased positive agreement for subtraction images. Subtraction MRI has potential as a visual aid increasing the sensitivity of ARIA-E assessment. However, in order to improve its usefulness isotropic acquisition and enhanced training are required. The ARIA-E rating scale may benefit from combining sulcal hyperintensity and swelling. • Subtraction technique can improve detection amyloid-related imaging-abnormalities with edema/effusion in Alzheimer's patients. • The value of ARIA-E detection, classification and monitoring using subtraction was assessed. • Validation of an established ARIA-E rating scale, recommendations for improvement are reported. • Complementary statistical methods were employed to measure accuracy, inter-rater-reliability and specific agreement.

Using the hydrophobic subtraction model to choose orthogonal columns for online comprehensive two-dimensional liquid chromatography

DEFF Research Database (Denmark)

Græsbøll, Rune; Nielsen, Nikoline Juul; Christensen, Jan H.

2014-01-01

A method for choosing orthogonal columns for a specific sample set in on-line comprehensive two-dimensional liquid chromatography (LC×LC) was developed on the basis of the hydrophobic subtraction model. The method takes into account the properties of the sample analytes by estimating new F...... neutral and 4 acidic oxygenated polycyclic aromatic compounds (PACs) and 3 nitrogen-containing PAC bases was measured isocratically on 12 columns. The isocratic runs were used to determine the hydrophobic subtraction model analyte parameters, and these were used to estimate new F-weights and predict...

Application of digital subtraction angiography in disease of large cardiac vessel

Energy Technology Data Exchange (ETDEWEB)

Arisawa, Jun; Sone, Shusuke; Morimoto, Shizuo; Ikezoe, Junpei; Higashibara, Tokuro; Hanayama, Masayuki

1983-06-01

Digital subtraction angiography (DSA) was performed in 31 cases of disease of large cardiac vessel. DSA was useful for the diagnosis of aortic aneurysm and malformation of large vessels, follow-up after A-C bypass operation and Blalock's shunt operation for tetralogy of Fallot and as an adjuvant modality in cardiac catheterization.

Application of digital subtraction angiography in disease of large cardiac vessel

International Nuclear Information System (INIS)

Arisawa, Jun; Sone, Shusuke; Morimoto, Shizuo; Ikezoe, Junpei; Higashibara, Tokuro; Hanayama, Masayuki

1983-01-01

Digital subtraction angiography (DSA) was performed in 31 cases of disease of large cardiac vessel. DSA was useful for the diagnosis of aortic aneurysm and malformation of large vessels, follow-up after A-C bypass operation and Blalock's shunt operation for tetralogy of Fallot and as an adjuvant modality in cardiac catheterization. (Chiba, N.)

Myocardial perfusion imaging by digital subtraction angiography

International Nuclear Information System (INIS)

Kadowaki, Hiroyuki; Ishikawa, Kinji; Ogai, Toshihiro; Katori, Ryo

1986-01-01

Several methods of digital subtraction angiography (DSA) were compared to determine which could better visualize regional myocardial perfusion using coronary angiography in seven patients with myocardial infarction, two with angina pectoris and five with normal coronary arteries. Satisfactory DSA was judged to be achieved if the shape of the heart on the mask film was identical to that on the live film and if both films were exactly superimposed. To obtain an identical mask film in the shape of each live film, both films were selected from the following three phases of the cardiac cycle; 1) at the R wave of the electrocardiogram, 2) 100 msec before the R wave, and 3) 200 msec before the R wave. The last two were superior for obtaining mask and live films which were similar in shape, because the cardiac motion in these phases was relatively small. Using these mask and live films, DSA was performed either with the continuous image mode (CI mode) or the time interval difference mode (TID mode). The overall perfusion of contrast medium through the artery to the vein was adequately visualized using the CI mode. Passage of contrast medium through the artery, capillary and vein was visualized at each phase using TID mode. Subtracted images were displayed and photographed, and the density of the contrast medium was adequate to display contour lines as in a relief map. Using this DSA, it was found that regional perfusion of the contrast medium was not always uniform in normal subjects, depending on the typography of the coronary artery. In all patients with anterior myocardial infarction, low perfusion was observed at the infarcted portion compared to the non-infarcted myocardium. In patients with inferior myocardial infarction, this low perfusion area was not observed because right coronary angiography was not subjected to DSA in this study. (J.P.N.)

N-jettiness subtractions for gg→H at subleading power

Energy Technology Data Exchange (ETDEWEB)

Moult, Ian [California Univ., Berkeley, CA (United States). Berkeley Center for Theoretical Physics; Lawrence Berkeley National Laboratory, CA (United States). Theoretical Physics Group; Rothen, Lorena; Tackmann, Frank J. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany). Gruppe Theorie; Stewart, Iain W. [Massachusetts Institute of Technology, Cambridge, MA (United States). Center for Theoretical Physics; Zhu, Hua Xing [Massachusetts Institute of Technology, Cambridge, MA (United States). Center for Theoretical Physics; Zhejiang Univ. (China). Dept. of Physics

2017-10-15

N-jettiness subtractions provide a general approach for performing fully-differential next-to-next-to-leading order (NNLO) calculations. Since they are based on the physical resolution variable N-jettiness, T{sub N}, subleading power corrections in τ =T{sub N}/Q, with Q a hard interaction scale, can also be systematically computed. We study the structure of power corrections for 0-jettiness, T{sub 0}, for the gg→H process. Using the soft-collinear effective theory we analytically compute the leading power corrections α{sub s}τ ln τ and α{sub s}{sup 2}τ ln{sup 3}τ (finding partial agreement with a previous result in the literature), and perform a detailed numerical study of the power corrections in the gg, gq, and q anti q channels. This includes a numerical extraction of the α{sub s}τ and α{sub s}{sup 2}τ ln{sup 2}τ corrections, and a study of the dependence on the T{sub 0} definition. Including such power suppressed logarithms significantly reduces the size of missing power corrections, and hence improves the numerical efficiency of the subtraction method. Having a more detailed understanding of the power corrections for both q anti q and gg initiated processes also provides insight into their universality, and hence their behavior in more complicated processes where they have not yet been analytically calculated.

N-jettiness subtractions for gg→H at subleading power

International Nuclear Information System (INIS)

Moult, Ian; Lawrence Berkeley National Laboratory, CA; Rothen, Lorena; Tackmann, Frank J.; Stewart, Iain W.; Zhu, Hua Xing; Zhejiang Univ.

2017-10-01

N-jettiness subtractions provide a general approach for performing fully-differential next-to-next-to-leading order (NNLO) calculations. Since they are based on the physical resolution variable N-jettiness, T N , subleading power corrections in τ =T N /Q, with Q a hard interaction scale, can also be systematically computed. We study the structure of power corrections for 0-jettiness, T 0 , for the gg→H process. Using the soft-collinear effective theory we analytically compute the leading power corrections α s τ ln τ and α s 2 τ ln 3 τ (finding partial agreement with a previous result in the literature), and perform a detailed numerical study of the power corrections in the gg, gq, and q anti q channels. This includes a numerical extraction of the α s τ and α s 2 τ ln 2 τ corrections, and a study of the dependence on the T 0 definition. Including such power suppressed logarithms significantly reduces the size of missing power corrections, and hence improves the numerical efficiency of the subtraction method. Having a more detailed understanding of the power corrections for both q anti q and gg initiated processes also provides insight into their universality, and hence their behavior in more complicated processes where they have not yet been analytically calculated.

Chromospheric Ca II H and K and H-alpha emission in single and binary stars of spectral types F6-M2

International Nuclear Information System (INIS)

Strassmeier, K.G.; Fekel, F.C.; Bopp, B.W.; Dempsey, R.C.; Henry, G.W.

1990-01-01

New observations of the Ca II H and K and H-epsilon region and/or the Balmer H-alpha line are presented for 100 mostly very active stars but also for weak or inactive stars with suspected activity. Correlations between chromospheric activity at Ca II H and K and H-alpha and effective surface temperature and rotation are identified, and several new stars with chromospheric Ca II H and K emission are discovered. No single activity-rotation relation can be derived for all luminosity classes, and there is clear evidence that evolved stars are generally more active than main-sequence stars of the same rotation period. Binary within the evolved stars appears to play no role, while main-sequence binary stars show generally higher levels of activity than their single counterparts. Chromospheric emission in the Ca II H and K lines depends on surface temperature in that flux declines with cooler temperature. 63 refs

Nonlinear ultrasonic imaging method for closed cracks using subtraction of responses at different external loads.

Science.gov (United States)

Ohara, Yoshikazu; Horinouchi, Satoshi; Hashimoto, Makoto; Shintaku, Yohei; Yamanaka, Kazushi

2011-08-01

To improve the selectivity of closed cracks for objects other than cracks in ultrasonic imaging, we propose an extension of a novel imaging method, namely, subharmonic phased array for crack evaluation (SPACE) as well as another approach using the subtraction of responses at different external loads. By applying external static or dynamic loads to closed cracks, the contact state in the cracks varies, resulting in an intensity change of responses at cracks. In contrast, objects other than cracks are independent of external load. Therefore, only cracks can be extracted by subtracting responses at different loads. In this study, we performed fundamental experiments on a closed fatigue crack formed in an aluminum alloy compact tension (CT) specimen using the proposed method. We examined the static load dependence of SPACE images and the dynamic load dependence of linear phased array (PA) images by simulating the external loads with a servohydraulic fatigue testing machine. By subtracting the images at different external loads, we show that this method is useful in extracting only the intensity change of responses related to closed cracks, while canceling the responses of objects other than cracks. Copyright © 2010 Elsevier B.V. All rights reserved.

Double-nuclide subtraction scintiscanning of the pancreas

International Nuclear Information System (INIS)

Streithoff, E.C.

1978-01-01

The paper intends to find out if there is a correlation between clinical pancreas diagnoses and diagnoses by subtraction scintiscanning; furthermore, the findings of scintiscanning are compared with those of radiological and sonographic methods. In order to get a picture of the efficiency of the methods applied, not only their accuracy is determined but also their validity sum and validity product. The best results are achieved here with angiography, ERCP, and sonography. In the case of pancreatic scintiscanning, an optimal result well above the international standard is only obtained for sensitivity. On the basis of these results, the indications for an optimal and useful application of pancreatic scintiscanning are determined. (orig./AJ) [de

[Design and development of the DSA digital subtraction workstation].

Science.gov (United States)

Peng, Wen-Xian; Peng, Tian-Zhou; Xia, Shun-Ren; Jin, Guang-Bo

2008-05-01

According to the patient examination criterion and the demands of all related departments, the DSA digital subtraction workstation has been successfully designed and is introduced in this paper by analyzing the characteristic of video source of DSA which was manufactured by GE Company and has no DICOM standard interface. The workstation includes images-capturing gateway and post-processing software. With the developed workstation, all images from this early DSA equipment are transformed into DICOM format and then are shared in different machines.

Synthesis, spectral and thermal studies of pyridyl adducts of Zn(II) and Cd(II) dithiocarbamates, and their use as single source precursors for ZnS and CdS nanoparticles

OpenAIRE

Onwudiwe, Damian C.; Strydom, Christien A.; Jordaan, Anine; Oluwafemi, Oluwatobi S.; Hosten, Eric

2014-01-01

The synthesis, spectroscopic characterisation, and thermal studies of pyridyl adducts of Zn(II) and Cd(II) complexes of N-ethyl-N-phenyl dithiocarbamate, represented as [ZnL2py] and [CdL2py2], are reported. Single-crystal X-ray structural analysis of the Zn compound showed that it is five-coordinate with four sulphurs from dithiocarbamate and one nitrogen from pyridine in a distorted square pyramidal geometry. The thermogravimetric studies indicate that the zinc and cadmium compou...

Videodensitometric assessment of right and left ventricular functions by digital subtraction angiography

International Nuclear Information System (INIS)

Ikeda, Hisao; Yoshiga, Osamu; Shibao, Keigo

1987-01-01

Intravenous digital subtraction (DS) ventriculography was performed in a series of 50 patients with heart diseases to determine right and left ventricular volumes and systolic indices. Right ventricular volume and right ventricular ejection fraction obtained by DS ventriculography were well correlated with those by geometric methods. In 43 patients with left ventricular ejection fraction of 55 % or greater, end-diastolic volume, stroke volume, and ejection fraction in the right ventricle did not differ from those in the left ventricle ; however, both the 1/3 ejection fraction and the peak ejection rate of the right ventricle were significantly lower than those of the left ventricle, suggesting the different modes of left and right ventricular contraction. In the other seven patients with chronic left ventricular failure, right ventricular systolic function may be preserved, even when left ventricular function is severely impaired. Digital subtraction ventriculography has proved to be a simple, useful method in the quanlitative and quantitative assessments of the right and left ventricles. (Namekawa, K.)

Ability of subtraction and dynamic MR imaging to detect breast tumors. Comparison with ultrasonography and mammography

International Nuclear Information System (INIS)

Terao, Eri; Takeuchi, Hiroaki; Iwamura, Akira; Murakami, Yoshitaka; Harada, Junta; Tada, Shinpei

1994-01-01

We evaluated the ability of subtraction and dynamic MR imaging to accurately detect breast tumors. Sixty-five breast carcinomas and 24 fibroadenomas were examined by an SE pulse sequence using a 0.2 Tesla unit. Subtraction MR images were obtained every minute during dynamic study with Gd-DTPA. Almost all breast tumors were seen as very bright masses, and the margin of the mass was clearly demonstrated on subtraction MR images. Breast carcinomas and fibroadenomas showed characteristic time-intensity curves on dynamic study. Time-intensity curves of the early peak type and plateau type were seen in 97% of breast carcinomas, while the gradually increasing type was seen in 92% of fibroadenomas. The detectability of breast carcinoma was 98% by MRI, 98% by ultrasonography, and 87% by mammography. That of fibroadenoma was 95% by MRI, 91% by ultrasonography and 60% by mammography. Sensitivity and specificity for breast carcinoma were 98% and 92% for MRI and 97% and 71% for ultrasonography. For fibroadenoma, they were 96% and 98% for MRI and 89% and 92% for ultrasonography. (author)

Ability of subtraction and dynamic MR imaging to detect breast tumors. Comparison with ultrasonography and mammography

Energy Technology Data Exchange (ETDEWEB)

Terao, Eri; Takeuchi, Hiroaki; Iwamura, Akira; Murakami, Yoshitaka; Harada, Junta; Tada, Shinpei (Jikei Univ., Tokyo (Japan). School of Medicine)

1994-09-01

We evaluated the ability of subtraction and dynamic MR imaging to accurately detect breast tumors. Sixty-five breast carcinomas and 24 fibroadenomas were examined by an SE pulse sequence using a 0.2 Tesla unit. Subtraction MR images were obtained every minute during dynamic study with Gd-DTPA. Almost all breast tumors were seen as very bright masses, and the margin of the mass was clearly demonstrated on subtraction MR images. Breast carcinomas and fibroadenomas showed characteristic time-intensity curves on dynamic study. Time-intensity curves of the early peak type and plateau type were seen in 97% of breast carcinomas, while the gradually increasing type was seen in 92% of fibroadenomas. The detectability of breast carcinoma was 98% by MRI, 98% by ultrasonography, and 87% by mammography. That of fibroadenoma was 95% by MRI, 91% by ultrasonography and 60% by mammography. Sensitivity and specificity for breast carcinoma were 98% and 92% for MRI and 97% and 71% for ultrasonography. For fibroadenoma, they were 96% and 98% for MRI and 89% and 92% for ultrasonography. (author).

Competitive adsorption of Pb(II), Cu(II), and Zn(II) ions onto hydroxyapatite-biochar nanocomposite in aqueous solutions

Science.gov (United States)

Wang, Yu-Ying; Liu, Yu-Xue; Lu, Hao-Hao; Yang, Rui-Qin; Yang, Sheng-Mao

2018-05-01

A hydroxyapatite-biochar nanocomposite (HAP-BC) was successfully fabricated and its physicochemical properties characterized. The analyses showed that HAP nanoparticles were successfully loaded on the biochar surface. The adsorption of Pb(II), Cu(II), and Zn(II) by HAP-BC was systematically studied in single and ternary metal systems. The results demonstrated that pH affects the adsorption of heavy metals onto HAP-BC. Regarding the adsorption kinetics, the pseudo-second-order model showed the best fit for all three heavy metal ions on HAP-BC. In both single and ternary metal ion systems, the adsorption isotherm of Pb(II) by HAP-BC followed Langmuir model, while those of Cu(II) and Zn(II) fitted well with Freundlich model. The maximum adsorption capacity for each tested metal by HAP-BC was higher than that of pristine rice straw biochar (especially for Pb(II)) or those of other reported adsorbents. Therefore, HAP-BC could explore as a new material for future application in heavy metal removal.

DNA damage by the cobalt (II) and zinc (II) complexes of ...

African Journals Online (AJOL)

Using the single cell gel electrophoresis method, the tetraazamacrocycle Zn(II) complex (Zn(II)-L) and the tetraazamacrocycle Co(II) complex (Co(II)-L) were investigated focusing on their DNA damage to Tetrahymena thermophila. When the cells were treated with the 0.05, 0.25 and 0.50 mg/ml Zn(II)-L, the tail length ...

Digital subtraction angiography in head and neck radiology

Energy Technology Data Exchange (ETDEWEB)

Carmody, R F; Seeger, J F; Smith, R L; Horsley, W W; Miller, R W

1984-07-01

Intravenous digital subtraction angiography (IVDSA) was used to evaluate 44 patients with suspected otolaryngologic abnormalities. Sixteen had IVDSA for pulsatile tinnitus or suspected glomus tumor of the petrous bone. Nine patients were evaluated because of pulsatile neck masses, and 12 others had suspected tumors of the neck, face, and paranasal sinuses. Seven had IVDSA following head and neck trauma. The technique of examination is described. The current indications of IVDSA in head and neck radiology are discussed. It is concluded that IVDSA is a suitable substitute for conventional angiography for many otolaryngologic conditions and, because of its safety, can be used more liberally.

Low-cost addition-subtraction sequences for the final exponentiation computation in pairings

DEFF Research Database (Denmark)

Guzmán-Trampe, Juan E; Cruz-Cortéz, Nareli; Dominguez Perez, Luis

2014-01-01

In this paper, we address the problem of finding low cost addition–subtraction sequences for situations where a doubling step is significantly cheaper than a non-doubling one. One application of this setting appears in the computation of the final exponentiation step of the reduced Tate pairing d...

Fourier Analysis of Single-Shot Dual-Energy X-ray Imaging Characteristics

International Nuclear Information System (INIS)

Kim, Jun Woo; Kim, Dong Woon; Kim, Ho Kyung

2016-01-01

The sandwich detector was realized by stacking two scintillator-based flat-panel detectors (FPDs) between which an intermediate copper (Cu) filter layer was placed to further enhance spectral energy separation. As a result, the proper selection of filter material and its thickness could be a trade-off between the extent of energy separation (hence, DE image quality) and image noise due to reduction in the number of x-ray quanta reaching the rear FPD. Although the conventional kVp-switching dual-shot method showed better image qualities than the single-shot method because of larger spectral energy separation, the motion-artifact-free DE image with reasonably good image quality was a potential prospect of the single-shot method. For the reliable and better use of the sandwich detector for specific imaging applications, the sandwich detector should be optimally designed with a proper selection of scintillator material and thickness in each detector layer (i.e. the front and rear detectors), and aforementioned intermediate filter material and thickness. It is noted that glue is used to adhere the fragile photodiode array onto the ceramic substrate and these glue patterns are apparent in the rear and DE images. The glue pattern in the rear image comes from the front FPD. Unlike the conventional ESF as shown in Fig. 3(a), the ESF obtained from the subtracted image showed an enhancement as shown in Fig. 3(b). Consequently, the MTF obtained from the subtraction ESF showed a bandpass filter characteristic, as shown in Fig. 3(c), unlike the conventional low-pass filter characteristic (i.e., monotonic decrease of MTF value with increasing the spatial frequency). This MTF characteristic is due to the subtraction of two images with different spatial resolving powers (i.e., different thicknesses of phosphors between the front and rear detectors) as can be seen in unsharp masking digital image processing, which subtracts Gaussian-blurred image from the original image

Fourier Analysis of Single-Shot Dual-Energy X-ray Imaging Characteristics

Energy Technology Data Exchange (ETDEWEB)

Kim, Jun Woo; Kim, Dong Woon; Kim, Ho Kyung [Pusan National University, Busan (Korea, Republic of)

2016-05-15

The sandwich detector was realized by stacking two scintillator-based flat-panel detectors (FPDs) between which an intermediate copper (Cu) filter layer was placed to further enhance spectral energy separation. As a result, the proper selection of filter material and its thickness could be a trade-off between the extent of energy separation (hence, DE image quality) and image noise due to reduction in the number of x-ray quanta reaching the rear FPD. Although the conventional kVp-switching dual-shot method showed better image qualities than the single-shot method because of larger spectral energy separation, the motion-artifact-free DE image with reasonably good image quality was a potential prospect of the single-shot method. For the reliable and better use of the sandwich detector for specific imaging applications, the sandwich detector should be optimally designed with a proper selection of scintillator material and thickness in each detector layer (i.e. the front and rear detectors), and aforementioned intermediate filter material and thickness. It is noted that glue is used to adhere the fragile photodiode array onto the ceramic substrate and these glue patterns are apparent in the rear and DE images. The glue pattern in the rear image comes from the front FPD. Unlike the conventional ESF as shown in Fig. 3(a), the ESF obtained from the subtracted image showed an enhancement as shown in Fig. 3(b). Consequently, the MTF obtained from the subtraction ESF showed a bandpass filter characteristic, as shown in Fig. 3(c), unlike the conventional low-pass filter characteristic (i.e., monotonic decrease of MTF value with increasing the spatial frequency). This MTF characteristic is due to the subtraction of two images with different spatial resolving powers (i.e., different thicknesses of phosphors between the front and rear detectors) as can be seen in unsharp masking digital image processing, which subtracts Gaussian-blurred image from the original image.

Use of images of ictal-inter-ictal SPECT subtraction superimposed on MRI in pharmaco-resistant partial epilepsies in infants

International Nuclear Information System (INIS)

Vera, P.; Kaminska, A.; Cieuta, C.; Mangin, F.; Frouin, V.; Dulac, O.; Chiron, C.

1997-01-01

To study the significance of ictal SPECT in the pre-surgical examination of infant epilepsies we have explored 16 infants aged 3 months to 18 years presenting partial pharmaco-resistant epilepsy. All of them have had an ictal SPECT under EEG - video recording than, two days after, an inter-ictal SPECT coupled to a 3D cerebral MRI. The perfusion tracer, the 99m Tc - ECD, was injected in average at 15 seconds after the outset of crisis. The image processing implied a matching of the two SPECT examinations by a 3D rigid superposition method, a normalization and than a inter-ictal-ictal image subtraction. Finally, the subtraction was matched and superimposed on the MRI. The SPECT subtraction image showed one or several centres of ictal hyper-output in 15 patients, while the separated visual ictal and inter-ictal images were contributory in 8 cases only. The 16. infant presented very short crises (<10 sec). In the cases when the outset point of crises could be established clinically (12 cases) and/or on EEG (8 cases) a hyper-output of concordant localization was recorded. In 5 infants who have had an electrocorticography, a concordance was obtained in all the cases except in an infant having very short crises the subtraction image did not show hyper-output. These preliminary results show that the ictal - inter-ictal SPECT subtraction images, adjusted on MRI, appears to be reliable in detecting the outset point of crises in infants and at the same time useful in guiding the positioning of intra-cranial electrodes prior to surgery intervention

Usefulness of computerized method for lung nodule detection on digital chest radiographs using similar subtraction images from different patients

International Nuclear Information System (INIS)

Aoki, Takatoshi; Oda, Nobuhiro; Yamashita, Yoshiko; Yamamoto, Keiji; Korogi, Yukunori

2012-01-01

Purpose: The purpose of this study is to evaluate the usefulness of a novel computerized method to select automatically the similar chest radiograph for image subtraction in the patients who have no previous chest radiographs and to assist the radiologists’ interpretation by presenting the “similar subtraction image” from different patients. Materials and methods: Institutional review board approval was obtained, and the requirement for informed patient consent was waived. A large database of approximately 15,000 normal chest radiographs was used for searching similar images of different patients. One hundred images of candidates were selected according to two clinical parameters and similarity of the lung field in the target image. We used the correlation value of chest region in the 100 images for searching the most similar image. The similar subtraction images were obtained by subtracting the similar image selected from the target image. Thirty cases with lung nodules and 30 cases without lung nodules were used for an observer performance test. Four attending radiologists and four radiology residents participated in this observer performance test. Results: The AUC for all radiologists increased significantly from 0.925 to 0.974 with the CAD (P = .004). When the computer output images were available, the average AUC for the residents was more improved (0.960 vs. 0.890) than for the attending radiologists (0.987 vs. 0.960). Conclusion: The novel computerized method for lung nodule detection using similar subtraction images from different patients would be useful to detect lung nodules on digital chest radiographs, especially for less experienced readers.

Temporal digital subtraction radiography with a personal computer digital workstation

International Nuclear Information System (INIS)

Kircos, L.; Holt, W.; Khademi, J.

1990-01-01

Technique have been developed and implemented on a personal computer (PC)-based digital workstation to accomplish temporal digital subtraction radiography (TDSR). TDSR is useful in recording radiologic change over time. Thus, this technique is useful not only for monitoring chronic disease processes but also for monitoring the temporal course of interventional therapies. A PC-based digital workstation was developed on a PC386 platform with add-in hardware and software. Image acquisition, storage, and processing was accomplished using 512 x 512 x 8- or 12-bit frame grabber. Software and hardware were developed to accomplish image orientation, registration, gray scale compensation, subtraction, and enhancement. Temporal radiographs of the jaws were made in a fixed and reproducible orientation between the x-ray source and image receptor enabling TDSR. Temporal changes secondary to chronic periodontal disease, osseointegration of endosseous implants, and wound healing were demonstrated. Use of TDSR for chest imaging was also demonstrated with identification of small, subtle focal masses that were not apparent with routine viewing. The large amount of radiologic information in images of the jaws and chest may obfuscate subtle changes that TDSR seems to identify. TDSR appears to be useful as a tool to record temporal and subtle changes in radiologic images

Potentiation of a p53-SLP vaccine by cyclophosphamide in ovarian cancer : A single-arm phase II study

NARCIS (Netherlands)

Vermeij, Renee; Leffers, Ninke; Hoogeboom, Baukje-Nynke; Hamming, Ineke L. E.; Wolf, Rinze; Reyners, Anna K. L.; Molmans, Barbara H. W.; Hollema, Harry; Bart, Joost; Drijfhout, Jan W.; Oostendorp, Jaap; van der Zee, Ate G. J.; Melief, Cornelis J.; van der Burg, Sjoerd H.; Daemen, Toos; Nijman, Hans W.

2012-01-01

The purpose of the current phase II single-arm clinical trial was to evaluate whether pretreatment with low-dose cyclophosphamide improves immunogenicity of a p53-synthetic long peptide (SLP) vaccine in patients with recurrent ovarian cancer. Patients with ovarian cancer with elevated serum levels

In vivo optical imaging of amblyopia: Digital subtraction autofluorescence and split-spectrum amplitude-decorrelation angiography.

Science.gov (United States)

Guo, Lei; Tao, Jun; Xia, Fan; Yang, Zhi; Ma, Xiaoli; Hua, Rui

2016-09-01

Amblyopia is a visual impairment that is attributed to either abnormal binocular interactions or visual deprivation. The retina and choroids have been shown to be involved in the development of amblyopia. The purpose of this study was to investigate the retinal and choroidal microstructural abnormalities of amblyopia using digital subtraction autofluorescence and split-spectrum amplitude-decorrelation angiography (SSADA) approaches. This prospective study included 44 eyes of 22 patients with unilateral amblyopia. All patients who received indirect ophthalmoscopy, combined depth imaging spectral domain optical coherence tomography (OCT), SSADA-OCT, and macular blue light (BL-) and near-infrared (NIR-) autofluorescences underwent pupil dilation. The subfoveal choroidal thickness (SFCT) was measured. BL- and NIR-autofluorescences were determined for all patients and used to generate subtraction images with ImageJ software. The superficial, deep layers of the retina, and inner choroid layer were required for SSADA-OCT. For the normal eyes, a regularly increasing signal was observed in the central macula based on the subtraction images. In contrast, a decreased signal for the central patch or a reduced peak was detected in 16 of 22 amblyopic eyes (72.7%). The mean SFCT of the amblyopic eyes was greater than that of the fellow normal eyes (399.25 ± 4.944 µm vs. 280.58 ± 6.491 µm, respectively, P autofluorescence. The mechanistic relationship of a thicker choroid and choroidal capillary atrophy with amblyopia remains to be described. The digital subtraction image confirmed the changes in the microstructure of the amblyopic retina as a supplementary approach to detect the progression of amblyopia. Lasers Surg. Med. 48:660-667, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

The Pedestrian Detection Method Using an Extension Background Subtraction about the Driving Safety Support Systems

Science.gov (United States)

Muranaka, Noriaki; Date, Kei; Tokumaru, Masataka; Imanishi, Shigeru

In recent years, the traffic accident occurs frequently with explosion of traffic density. Therefore, we think that the safe and comfortable transportation system to defend the pedestrian who is the traffic weak is necessary. First, we detect and recognize the pedestrian (the crossing person) by the image processing. Next, we inform all the drivers of the right or left turn that the pedestrian exists by the sound and the image and so on. By prompting a driver to do safe driving in this way, the accident to the pedestrian can decrease. In this paper, we are using a background subtraction method for the movement detection of the movement object. In the background subtraction method, the update method in the background was important, and as for the conventional way, the threshold values of the subtraction processing and background update were identical. That is, the mixing rate of the input image and the background image of the background update was a fixation value, and the fine tuning which corresponded to the environment change of the weather was difficult. Therefore, we propose the update method of the background image that the estimated mistake is difficult to be amplified. We experiment and examines in the comparison about five cases of sunshine, cloudy, evening, rain, sunlight change, except night. This technique can set separately the threshold values of the subtraction processing and background update processing which suited the environmental condition of the weather and so on. Therefore, the fine tuning becomes possible freely in the mixing rate of the input image and the background image of the background update. Because the setting of the parameter which suited an environmental condition becomes important to minimize mistaking percentage, we examine about the setting of a parameter.

Infinity subtraction in a quantum field theory of charges and monopoles

International Nuclear Information System (INIS)

Panagiotakopoulos, C.

1982-03-01

Subtraction of ultraviolet infinities in Zwanziger's local quantum field theory of charges and monopoles is described. It involves an infinite number of graphs. The whole programme rests on the assumption that the infinite summations involved do not give rise to pathological situations and the Ward identities are satisfied even after the string cancellations. The resulting finite theory is Lorentz invariant. (author)

Digital subtraction angiography and intraarterial contrast medium injection for coronary examinations

Energy Technology Data Exchange (ETDEWEB)

Tobio, R; Kallmeyer, C; Castello, J

1985-01-01

Digital subtraction angiography (DSA) is an established method of vasography, most extensively used as i.v. DSA. Intraarterial injection, however, applying selective or non-selective contrast medium injection, seems to be at least as important a technique although it has not yet met with corresponding interest. The article explains advantages of the technique for angiographic examinations, in particular of coronary angiography.

Centrically reordered inversion recovery half-Fourier single-shot turbo spin-echo sequence: improvement of the image quality of oxygen-enhanced MRI

International Nuclear Information System (INIS)

Ohno, Yoshiharu; Hatabu, Hiroto; Higashino, Takanori; Kawamitsu, Hideaki; Watanabe, Hirokazu; Takenaka, Daisuke; Cauteren, Marc van; Sugimura, Kazuro

2004-01-01

Purpose: The purpose of the study presented here was to determine the improvement in image quality of oxygen-enhanced magnetic resonance (MR) subtraction imaging obtained with a centrically reordered inversion recovery half-Fourier single-shot turbo spin-echo (c-IR-HASTE) sequence compared with that obtained with a conventional sequentially reordered inversion recovery single-shot HASTE (s-IR-HASTE) sequence for pulmonary imaging. Materials and methods: Oxygen-enhanced MR imaging using a 1.5 T whole body scanner was performed on 12 healthy, non-smoking volunteers. Oxygen-enhanced MR images were obtained with the coronal two-dimensional (2D) c-IR-HASTE sequence and 2D s-IR-HASTE sequence combined with respiratory triggering. For a 256x256 matrix, 132 phase-encoding steps were acquired including four steps for phase correction. Inter-echo spacing for each sequence was 4.0 ms. The effective echo time (TE) for c-IR-HASTE was 4.0 ms, and 16 ms for s-IR-HASTE. The inversion time (TI) was 900 ms. To determine the improvement in oxygen-enhanced MR subtraction imaging by c-IR-HASTE, CNRs of subtraction image, overall image quality, and image degradation of the c-IR-HASTE and s-IR-HASTE techniques were statistically compared. Results: CNR, overall image quality, and image degradation of c-IR-HASTE images showed significant improvement compared to those s-IR-HASTE images (P<0.05). Conclusion: Centrically reordered inversion recovery half-Fourier single-shot turbo spin-echo (c-IR-HASTE) sequence enhanced the signal from the lung and improved the image quality of oxygen-enhanced MR subtraction imaging

VizieR Online Data Catalog: SNe II light curves & spectra from the CfA (Hicken+, 2017)

Science.gov (United States)

Hicken, M.; Friedman, A. S.; Blondin, S.; Challis, P.; Berlind, P.; Calkins, M.; Esquerdo, G.; Matheson, T.; Modjaz, M.; Rest, A.; Kirshner, R. P.

2018-01-01

Since all of the optical photometry reported here was produced as part of the CfA3 and CfA4 processing campaigns, see Hicken+ (2009, J/ApJ/700/331) and Hicken+ (2012, J/ApJS/200/12) for greater details on the instruments, observations, photometry pipeline, calibration, and host-galaxy subtraction used to create the CfA SN II light curves. (8 data files).

Dual isotope, single acquisition parathyroid imaging

International Nuclear Information System (INIS)

Triantafillou, M.; McDonald, H.J.

1998-01-01

Full text: Nuclear Medicine parathyroid imaging using Thallium-201(TI) and Technetium-99m(Tc) is an often used imaging modality for the detection of parathyroid adenomas and hyper parathyroidism. The conventional Tl/Tc subtraction technique requires 2 separate injections and acquisitions which are then normalised and subtracted from each other. This lengthy technique is uncomfortable for patients and can result in false positive scan results due to patient movement between and during the acquisition process. We propose a simplified injection and single acquisition technique, that reduces the chance of movement and thus reduces the chance of false positive scan results. The technique involves the injection of Tc followed by the Tl injection 10 minutes later. After a further 10 min wait, imaging is performed using a dual isotope acquisition, with window (W) 1 set on 140 keV 20%W 5% off peak and W2 peaked for 70 keV 20%W., acquired for 10 minutes. We have imaged 27 patients with this technique, 15 had positive parathyroid imaging. Of the 15, 11 had positive ultrasound correlation. Of the remaining 4, 2 have had positive surgical findings for adenomas, the other 2 are awaiting follow-up. Of the 12 patients with negative parathyroid imaging, 2 have been shown to be false - negative with surgery. In conclusion, the single acquisition technique suggested by us is a valid method of imaging parathyroids that reduces the chance of false positive results due to movement

Association between single nucleotide polymorphism of apoVLDL-II ...

African Journals Online (AJOL)

ONOS

2010-07-05

Jul 5, 2010 ... Very low density apolipoprotein-II (apoVLDL-II) is a major polypeptide component of avian VLDL. The function of apoVLDL-II is the transport of neutral lipids (triacylglycerol) in the form of VLDL in the plasma. The apoVLDLII gene is dormant in embryos, chicks and roosters but can be activated by estrogen.

Digital subtraction angiography in 105 living renal transplant donors

International Nuclear Information System (INIS)

Suh, Ho Jong; Oh, Kyung Seung; Kim, So Sun; Huh, Jin Do; Kim, Ho Joon; Chun, Byung Hee; Joh, Young Duck

1989-01-01

In order to analyze the number and length of the renal arteries and to evaluate abnormalities of the renal parenchyma and vessel, digital subtraction angiogram images of 105 potential renal donors (45 men and 60 women aged 17-66 years) were studied retrospectively. For the entire series, 31 donors had multiple renal arteries on one side (15 on the left, 11 on the right) and 5 donors on the both sides. 89 donors were family related either parents or siblings of recipients. The estimation of the length of the renal artery was based on the mean height of the second lumbar vertebral body (L2). The right renal artery is significant longer than on the left and measured more than the height of L2 vertebral body in 84 cases on the right and 60 cases on the left. Twenty two donors underwent right nephrectomy due to presence of multiple renal arteries on the left (N=14), proximal bifurcation of left main renal artery (N=3), and young females in reproductive age (N=5). Unexpected abnormalities found with angiogram were seen in 7 cases and they include renal artery stenosis (N=2), renal cysts (N=4) and focal infarction (N=1). In cases of the renal cysts and focal infarction, there were no serious complications related to the abnormalities. It is conclude that intra-arterial digital subtraction angiography is safe and efficient method to image renal anatomy of the potential renal donors

Clinical use of the ABO-Scoring Index: reliability and subtraction frequency.

Science.gov (United States)

Lieber, William S; Carlson, Sean K; Baumrind, Sheldon; Poulton, Donald R

2003-10-01

This study tested the reliability and subtraction frequency of the study model-scoring system of the American Board of Orthodontists (ABO). We used a sample of 36 posttreatment study models that were selected randomly from six different orthodontic offices. Intrajudge and interjudge reliability was calculated using nonparametric statistics (Spearman rank coefficient, Wilcoxon, Kruskal-Wallis, and Mann-Whitney tests). We found differences ranging from 3 to 6 subtraction points (total score) for intrajudge scoring between two sessions. For overall total ABO score, the average correlation was .77. Intrajudge correlation was greatest for occlusal relationships and least for interproximal contacts. Interjudge correlation for ABO score averaged r = .85. Correlation was greatest for buccolingual inclination and least for overjet. The data show that some judges, on average, were much more lenient than others and that this resulted in a range of total scores between 19.7 and 27.5. Most of the deductions were found in the buccal segments and most were related to the second molars. We present these findings in the context of clinicians preparing for the ABO phase III examination and for orthodontists in their ongoing evaluation of clinical results.

Clinical application of digital subtraction angiography for arterial portography

International Nuclear Information System (INIS)

Ohtomo, Kuni; Furui, Shigeru; Yashiro, Naofumi; Itai, Yuji; Iio, Masahiro

1983-01-01

Intra-arterial digital subtraction portography(IADSP) after superior mesenteric artery injection was described. A total dose of 15 ml to 20 ml of 76% contrast medium was injected at a rate of 5 ml/sec in 14 cases (9 hepatomas, 2 metastatic liver tumors, 2 cavernous hemangiomas, 1 liver cirrhosis). In 11 cases, portal venous system was clearly demonstrated by IADSP. In 8 hepatomas tumor thrombus of portal venous system could be ruled out by IADSP and embolization therapy was carried out. IADSP was also useful for demonstrating esophageal varix and splenorenal shunt. (author)

Digital subtraction angiography in head and neck radiology

International Nuclear Information System (INIS)

Carmody, R.F.; Seeger, J.F.; Smith, R.L.; Horsley, W.W.; Miller, R.W.

1984-01-01

Intravenous digital subtraction angiography (IVDSA) was used to evaluate 44 patients with suspected otolaryngologic abnormalities. Sixteen had IVDSA for pulsatile tinnitus or suspected glomus tumor of the petrous bone. Nine patients were evaluated because of pulsatile neck masses, and 12 others had suspected tumors of the neck, face, and paranasal sinuses. Seven had IVDSA following head and neck trauma. The technique of examination is described. The current indications of IVDSA in head and neck radiology are discussed. It is concluded that IVDSA is a suitable substitute for conventional angiography for many otolaryngologic conditions and, because of its safety, can be used more liberally. (orig.)

[Clinical values of hemodynamics assessment by parametric color coding of digital subtraction angiography before and after endovascular therapy for critical limb ischaemia].

Science.gov (United States)

Su, Haobo; Lou, Wensheng; Gu, Jianping

2015-10-06

To investigate the feasibility of parametric color coding of digital subtraction angiography (Syngo iFlow) for hemodynamics assessment in patients with critical limb ischemia in pre- and post-endovascular therapy. To explore the correlation between Syngo iFlow and the conventional techniques. from January 2013 to December 2014, Clinical data of 21 patients with TASC II type B and type C femoropopliteal arteriosclerotic occlusive disease who were treated by percutaneous transluminal angioplasty and/or primary stent implantation in Nanjing first hospital were analyzed retrospectively. Of these patients there were 10 males and 11 females with an average age of (72±6) years (range from 58-85 years). The treatment efficacy was assessed by the variation of a series of clinical symptoms indexes (such as pain score, cold sensation score and intermittent claudication score), ankle braehial index (ABI) and transcutaneous oxygen pressure (TcPO2). Angiography was performed with the same protocol before and after treatment and parametric color coding of digital subtraction angiography was created by Syngo iFlow software on a dedicated workstation. The time to peak (TTP) of artery and tissue perfusion selected at the same regions of foot and ankle were measured and analyzed to evaluate the improvement of microcirculation and hemodynamics of the ischemic limb. The correlations between Syngo iFlow and the traditional clinical evaluation methods were explored using the Spearman rank correlation test. All patients (21 limbs) underwent successful endovaseular therapy. The mean pain score, cold sensation score, intermittent claudication score, ABI and TcPO2 before treatment were (0.48±0.68), (2.71±0.72), (2.86±0.85), ABI (0.33±0.07), TcPO2 (26.83±3.41) mmHg. While 1 week after treatment all above indicators were (2.57±0.93), (0.33±0.48), (0.90±0.54), (0.69±0.11), TcPO2 (53.75±3.60) mmHg respectively. There were significant statistical differences between pre- and post

Confirmation of T1-Bright Vein of Galen Aneurysm Spontaneous Thrombosis by Subtraction Magnetic Resonance Venography: A Case Report

Energy Technology Data Exchange (ETDEWEB)

Irfan, M.; Lohman, B.; McKinney, A.M. (Dept. of Radiology/Neuroradiology, Univ. of Minnesota, Minneapolis, Minnesota (United States))

2009-08-15

Spontaneous thrombosis of a vein of Galen aneurysmal malformation (VOGM) is rare. We describe a 2-month-old patient with a patent VOGM and hydrocephalus, also confirmed patent at 6 months, but with subsequent lack of filling on pre-embolization catheter digital subtraction angiography (DSA) at 9 months' age. Due to the presence of T1- and T2-bright signal, noncontrast T1-weighted images (T1WI), T2-weighted images (T2WI), two-dimensional (2D) time-of-flight (TOF) magnetic resonance venography (MRV), and postcontrast T1WI were ambiguous for patency. However, subtracting the pre- from the postcontrast MRV images confirmed closure compared to subtracted images at 6 months' age. The factors contributing to thrombosis were likely a combination of a disproportionately small straight sinus, ventriculostomy, and contrast medium from DSA.

Intra-arterial digital subtraction angiography in the diagnosis of insulinomas

International Nuclear Information System (INIS)

Moulopoulou, A.; Vlahos, L.

1988-01-01

Two cases of surgically proved benign insulinoma of the pancreas were correctly localized with intra-arterial digital subtraction angiography (IA-DSA) of the coeliac and the superior mesenteric artery, while the respective dynamic computed tomography (CT) and ultrasound (US) examinations were negative. In a third case of organic hyperinsulinism, IA-DSA, CT and US suggested a pancreatic islet-cell tumor, but the histological examination of the resected suspicious area was that of focal hyperplasia. 17 refs.; 3 figs

Experimental test of the strongly nonclassical character of a noisy squeezed single-photon state

DEFF Research Database (Denmark)

Jezek, M.; Tipsmark, A.; Dong, R.

2012-01-01

We experimentally verify the quantum non-Gaussian character of a conditionally generated noisy squeezed single-photon state with a positive Wigner function. Employing an optimized witness based on probabilities of squeezed vacuum and squeezed single-photon states, we prove that the state cannot...... be expressed as a mixture of Gaussian states. In our experiment, the non-Gaussian state is generated by conditional subtraction of a single photon from a squeezed vacuum state. The state is probed with a homodyne detector and the witness is determined by averaging a suitable pattern function over the measured...

Quantifying the relative contributions of divisive and subtractive feedback to rhythm generation.

Directory of Open Access Journals (Sweden)

Joël Tabak

2011-04-01

Full Text Available Biological systems are characterized by a high number of interacting components. Determining the role of each component is difficult, addressed here in the context of biological oscillations. Rhythmic behavior can result from the interplay of positive feedback that promotes bistability between high and low activity, and slow negative feedback that switches the system between the high and low activity states. Many biological oscillators include two types of negative feedback processes: divisive (decreases the gain of the positive feedback loop and subtractive (increases the input threshold that both contribute to slowly move the system between the high- and low-activity states. Can we determine the relative contribution of each type of negative feedback process to the rhythmic activity? Does one dominate? Do they control the active and silent phase equally? To answer these questions we use a neural network model with excitatory coupling, regulated by synaptic depression (divisive and cellular adaptation (subtractive feedback. We first attempt to apply standard experimental methodologies: either passive observation to correlate the variations of a variable of interest to system behavior, or deletion of a component to establish whether a component is critical for the system. We find that these two strategies can lead to contradictory conclusions, and at best their interpretive power is limited. We instead develop a computational measure of the contribution of a process, by evaluating the sensitivity of the active (high activity and silent (low activity phase durations to the time constant of the process. The measure shows that both processes control the active phase, in proportion to their speed and relative weight. However, only the subtractive process plays a major role in setting the duration of the silent phase. This computational method can be used to analyze the role of negative feedback processes in a wide range of biological rhythms.

A Monte Carlo simulation study of an improved K-edge log-subtraction X-ray imaging using a photon counting CdTe detector

Energy Technology Data Exchange (ETDEWEB)

Lee, Youngjin, E-mail: radioyoungj@gmail.com [Department of Radiological Science, Eulji University, 553, Sanseong-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do (Korea, Republic of); Lee, Amy Candy [Department of Mathematics and Statistics, McGill University (Canada); Kim, Hee-Joung [Department of Radiological Science and Radiation Convergence Engineering, Yonsei University (Korea, Republic of)

2016-09-11

Recently, significant effort has been spent on the development of photons counting detector (PCD) based on a CdTe for applications in X-ray imaging system. The motivation of developing PCDs is higher image quality. Especially, the K-edge subtraction (KES) imaging technique using a PCD is able to improve image quality and useful for increasing the contrast resolution of a target material by utilizing contrast agent. Based on above-mentioned technique, we presented an idea for an improved K-edge log-subtraction (KELS) imaging technique. The KELS imaging technique based on the PCDs can be realized by using different subtraction energy width of the energy window. In this study, the effects of the KELS imaging technique and subtraction energy width of the energy window was investigated with respect to the contrast, standard deviation, and CNR with a Monte Carlo simulation. We simulated the PCD X-ray imaging system based on a CdTe and polymethylmethacrylate (PMMA) phantom which consists of the various iodine contrast agents. To acquired KELS images, images of the phantom using above and below the iodine contrast agent K-edge absorption energy (33.2 keV) have been acquired at different energy range. According to the results, the contrast and standard deviation were decreased, when subtraction energy width of the energy window is increased. Also, the CNR using a KELS imaging technique is higher than that of the images acquired by using whole energy range. Especially, the maximum differences of CNR between whole energy range and KELS images using a 1, 2, and 3 mm diameter iodine contrast agent were acquired 11.33, 8.73, and 8.29 times, respectively. Additionally, the optimum subtraction energy width of the energy window can be acquired at 5, 4, and 3 keV for the 1, 2, and 3 mm diameter iodine contrast agent, respectively. In conclusion, we successfully established an improved KELS imaging technique and optimized subtraction energy width of the energy window, and based on

Characterization of unknown genetic modifications using high throughput sequencing and computational subtraction

Directory of Open Access Journals (Sweden)

Butenko Melinka A

2009-10-01

Full Text Available Abstract Background When generating a genetically modified organism (GMO, the primary goal is to give a target organism one or several novel traits by using biotechnology techniques. A GMO will differ from its parental strain in that its pool of transcripts will be altered. Currently, there are no methods that are reliably able to determine if an organism has been genetically altered if the nature of the modification is unknown. Results We show that the concept of computational subtraction can be used to identify transgenic cDNA sequences from genetically modified plants. Our datasets include 454-type sequences from a transgenic line of Arabidopsis thaliana and published EST datasets from commercially relevant species (rice and papaya. Conclusion We believe that computational subtraction represents a powerful new strategy for determining if an organism has been genetically modified as well as to define the nature of the modification. Fewer assumptions have to be made compared to methods currently in use and this is an advantage particularly when working with unknown GMOs.

SPEAR II performance

International Nuclear Information System (INIS)

Paterson, J.M.

1975-01-01

The single beam and colliding beam performance of the SLAC electron-positron storage ring SPEAR II is described. The sevenfold increase in harmonic number in SPEAR II in comparison to SPEAR I has made significant changes in single beam behavior. Strong synchrobetatron resonances and a new transverse instability are observed, and our first studies of these phenomena are described. Measurements on current dependent bunch lengthening are presented. (auth)

Signal-to-noise ratio measurement in parallel MRI with subtraction mapping and consecutive methods

International Nuclear Information System (INIS)

Imai, Hiroshi; Miyati, Tosiaki; Ogura, Akio; Doi, Tsukasa; Tsuchihashi, Toshio; Machida, Yoshio; Kobayashi, Masato; Shimizu, Kouzou; Kitou, Yoshihiro

2008-01-01

When measuring the signal-to-noise ratio (SNR) of an image the used parallel magnetic resonance imaging, it was confirmed that there was a problem in the application of past SNR measurement. With the method of measuring the noise from the background signal, SNR with parallel imaging was higher than that without parallel imaging. In the subtraction method (NEMA standard), which sets a wide region of interest, the white noise was not evaluated correctly although SNR was close to the theoretical value. We proposed two techniques because SNR in parallel imaging was not uniform according to inhomogeneity of the coil sensitivity distribution and geometry factor. Using the first method (subtraction mapping), two images were scanned with identical parameters. The SNR in each pixel divided the running mean (7 by 7 pixels in neighborhood) by standard deviation/√2 in the same region of interest. Using the second (consecutive) method, more than fifty consecutive scans of the uniform phantom were obtained with identical scan parameters. Then the SNR was calculated from the ratio of mean signal intensity to the standard deviation in each pixel on a series of images. Moreover, geometry factors were calculated from SNRs with and without parallel imaging. The SNR and geometry factor using parallel imaging in the subtraction mapping method agreed with those of the consecutive method. Both methods make it possible to obtain a more detailed determination of SNR in parallel imaging and to calculate the geometry factor. (author)

Detection of simulated pulmonary nodules by single-exposure dual-energy computed radiography of the chest: effect of a computer-aided diagnosis system (Part 2)

International Nuclear Information System (INIS)

Kido, Shoji; Kuriyama, Keiko; Kuroda, Chikazumi; Nakamura, Hironobu; Ito, Wataru; Shimura, Kazuo; Kato, Hisatoyo

2002-01-01

Objective: To evaluate the performance of the computer-aided diagnosis (CAD) scheme on the detection of pulmonary nodules (PNs) in single-exposure dual-energy subtraction computed radiography (CR) images of the chest, and to evaluate the effect of this CAD scheme on radiologists' detectabilities. Methods and material: We compared the detectability by the CAD scheme with the detectability by 12 observers by using conventional CR (C-CR) and bone-subtracted CR (BS-CR) images of 25 chest phantoms with a low-contrast nylon nodule. Results: Both in the CAD scheme and for the observers, the detectability of BS-CR images was superior to that of C-CR images (P<0.005). The detection performance of the CAD scheme was equal to that of the observers. The nodules detected by the CAD did not necessarily coincide with those by the observers. Thus, if observers can use the results of the CAD system as a 'second opinion', their detectabilities increase. Conclusion: The CAD system for detection of PNs in the single-exposure dual-energy subtraction method is promising for improving radiologists' detectabilities of PNs

Real-time digital x-ray subtraction imaging

International Nuclear Information System (INIS)

Mistretta, C.A.

1982-01-01

The invention provides a method of producing visible difference images derived from an X-ray image of an anatomical subject, comprising the steps of directing X-rays through the anatomical subject for producing an image, converting the image into television fields comprising trains of on-going video signals, digitally storing and integrating the on-going video signals over a time interval corresponding to several successive television fields and thereby producing stored and integrated video signals, recovering the video signals from storage and producing integrated video signals, producing video difference signals by performing a subtraction between the integrated video signals and the on-going video signals outside the time interval, and converting the difference signals into visible television difference images representing on-going changes in the X-ray image

(18)F-alfatide II and (18)F-FDG dual-tracer dynamic PET for parametric, early prediction of tumor response to therapy.

Science.gov (United States)

Guo, Jinxia; Guo, Ning; Lang, Lixin; Kiesewetter, Dale O; Xie, Qingguo; Li, Quanzheng; Eden, Henry S; Niu, Gang; Chen, Xiaoyuan

2014-01-01

A single dynamic PET acquisition using multiple tracers administered closely in time could provide valuable complementary information about a tumor's status under quasiconstant conditions. This study aimed to investigate the utility of dual-tracer dynamic PET imaging with (18)F-alfatide II ((18)F-AlF-NOTA-E[PEG4-c(RGDfk)]2) and (18)F-FDG for parametric monitoring of tumor responses to therapy. We administered doxorubicin to one group of athymic nude mice with U87MG tumors and paclitaxel protein-bound particles to another group of mice with MDA-MB-435 tumors. To monitor therapeutic responses, we performed dual-tracer dynamic imaging, in sessions that lasted 90 min, starting with injection via the tail vein catheters with (18)F-alfatide II, followed 40 min later by (18)F-FDG. To achieve signal separation of the 2 tracers, we fit a 3-compartment reversible model to the time-activity curve of (18)F-alfatide II for the 40 min before (18)F-FDG injection and then extrapolated to 90 min. The (18)F-FDG tumor time-activity curve was isolated from the 90-min dual-tracer tumor time-activity curve by subtracting the fitted (18)F-alfatide II tumor time-activity curve. With separated tumor time-activity curves, the (18)F-alfatide II binding potential (Bp = k3/k4) and volume of distribution (VD) and (18)F-FDG influx rate ((K1 × k3)/(k2 + k3)) based on the Patlak method were calculated to validate the signal recovery in a comparison with 60-min single-tracer imaging and to monitor therapeutic response. The transport and binding rate parameters K1-k3 of (18)F-alfatide II, calculated from the first 40 min of the dual-tracer dynamic scan, as well as Bp and VD correlated well with the parameters from the 60-min single-tracer scan (R(2) > 0.95). Compared with the results of single-tracer PET imaging, (18)F-FDG tumor uptake and influx were recovered well from dual-tracer imaging. On doxorubicin treatment, whereas no significant changes in static tracer uptake values of (18)F-alfatide II

Averaged subtracted polarization imaging for endoscopic diagnostics of surface microstructures on translucent mucosae

Science.gov (United States)

Kanamori, Katsuhiro

2016-07-01

An endoscopic image processing technique for enhancing the appearance of microstructures on translucent mucosae is described. This technique employs two pairs of co- and cross-polarization images under two different linearly polarized lights, from which the averaged subtracted polarization image (AVSPI) is calculated. Experiments were then conducted using an acrylic phantom and excised porcine stomach tissue using a manual experimental setup with ring-type lighting, two rotating polarizers, and a color camera; better results were achieved with the proposed method than with conventional color intensity image processing. An objective evaluation method that uses texture analysis was developed and used to evaluate the enhanced microstructure images. This paper introduces two types of online, rigid-type, polarimetric endoscopic implementations using a polarized ring-shaped LED and a polarimetric camera. The first type uses a beam-splitter-type color polarimetric camera, and the second uses a single-chip monochrome polarimetric camera. Microstructures on the mucosa surface were enhanced robustly with these online endoscopes regardless of the difference in the extinction ratio of each device. These results show that polarimetric endoscopy using AVSPI is both effective and practical for hardware implementation.

Matching of singly- and doubly-unresolved limits of tree-level QCD squared matrix elements

Energy Technology Data Exchange (ETDEWEB)

Somogyi, Gabor [University of Debrecen and Institute of Nuclear Research of the Hungarian Academy of Sciences, H-4001 Debrecen, PO Box 51 (Hungary); Trocsanyi, Zoltan [University of Debrecen and Institute of Nuclear Research of the Hungarian Academy of Sciences, H-4001 Debrecen, PO Box 51 (Hungary); Duca, Vittorio Del [Istituto Nazionale di Fisica Nucleare, Sez. di Torino, via P. Giuria, 1 - 10125 Torino (Italy)

2005-06-01

We describe how to disentangle the singly- and doubly-unresolved (soft and/or collinear) limits of tree-level QCD squared matrix elements. Using the factorization formulae presented in this paper, we outline a viable general subtraction scheme for computing next-to-next-to-leading order corrections for electron-positron annihilation into jets.

Application of the singularity subtraction method for (d,p) reactions on light nuclei

International Nuclear Information System (INIS)

Borbely, I.

1974-01-01

It is shown that the method of subtraction the nearest singularity can be used successfully for data processing of (d,p) reactions. The data on the nuclear structure, thus obtained, can then be used for a more efficient study of the reaction mechanism with the use of traditional methods

The identification of genes specific to Prevotella intermedia and Prevotella nigrescens using genomic subtractive hybridization.

Science.gov (United States)

Masakiyo, Yoshiaki; Yoshida, Akihiro; Shintani, Yasuyuki; Takahashi, Yusuke; Ansai, Toshihiro; Takehara, Tadamichi

2010-06-01

Prevotella intermedia and Prevotella nigrescens, which are often isolated from periodontal sites, were once considered two different genotypes of P. intermedia. Although the genomic sequence of P. intermedia was determined recently, little is known about the genetic differences between P. intermedia and P. nigrescens. The subtractive hybridization technique is a powerful method for generating a set of DNA fragments differing between two closely related bacterial strains or species. We used subtractive hybridization to identify the DNA regions specific to P. intermedia ATCC 25611 and P. nigrescens ATCC 25261. Using this method, four P. intermedia ATCC 25611-specific and three P. nigrescens ATCC 25261-specific regions were determined. From the species-specific regions, insertion sequence (IS) elements were isolated for P. intermedia. IS elements play an important role in the pathogenicity of bacteria. For the P. intermedia-specific regions, the genes adenine-specific DNA-methyltransferase and 8-amino-7-oxononanoate synthase were isolated. The P. nigrescens-specific region contained a Flavobacterium psychrophilum SprA homologue, a cell-surface protein involved in gliding motility, Prevotella melaninogenica ATCC 25845 glutathione peroxide, and Porphyromonas gingivalis ATCC 33277 leucyl-tRNA synthetase. The results demonstrate that the subtractive hybridization technique was useful for distinguishing between the two closely related species. Furthermore, this technique will contribute to our understanding of the virulence of these species. 2009 Elsevier Ltd. All rights reserved.

Reaction of single-standard DNA with hydroxyl radical generated by iron(II)-ethylenediaminetetraacetic acid

International Nuclear Information System (INIS)

Prigodich, R.V.; Martin, C.T.

1990-01-01

This study demonstrates that the reaction of Fe(II)-EDTA and hydrogen peroxide with the single-stranded nucleic acids d(pT) 70 and a 29-base sequence containing a mixture of bases results in substantial damage which is not directly detected by gel electrophoresis. Cleavage of the DNA sugar backbone is enhanced significantly after the samples are incubated at 90 degree C in the presence of piperidine. The latter reaction is used in traditional Maxam-Gilbert DNA sequencing to detect base damage, and the current results are consistent with reaction of the hydroxyl radical with the bases in single-stranded DNA (although reaction with sugar may also produce adducts that are uncleaved but labile to cleavage by piperidine). We the authors propose that hydroxyl radicals may react preferentially with the nucleic acid bases in ssDNA and that reaction of the sugars in dsDNA is dominant because the bases are sequestered within the double helix. These results have implications both for the study of single-stranded DNA binding protein binding sites and for the interpretation of experiments using the hydroxyl radical to probe DNA structure or to footprint double-stranded DNA binding protein binding sites

The reduction of motion artifacts in digital subtraction angiography by geometrical image transformation

International Nuclear Information System (INIS)

Fitzpatrick, J.M.; Pickens, D.R.; Mandava, V.R.; Grefenstette, J.J.

1988-01-01

In the diagnosis of arteriosclerosis, radio-opaque dye is injected into the interior of the arteries to make them visible. Because of its increased contrast sensitivity, digital subtraction angiography has the potential for providing diagnostic images of arteries with reduced dye volumes. In the conventional technique, a mask image, acquired before the introduction of the dye, is subtracted from the contrast image, acquired after the dye is introduced, to produce a difference image in which only the dye in the arteries is visible. The usefulness of this technique has been severely limited by the image degradation caused by patient motion during image acquisition. This motion produces artifacts in the difference image that obscure the arteries. One technique for dealing with the problem is to reduce the degradation by means of image registration. The registration is carried out by means of a geometrical transformation of the mask image before subtraction so that it is in registration with the contrast image. This paper describes a technique for determining an optimal transformation. The authors employ a one-to-one elastic mapping and the Jacobian of that mapping to produce a geometrical image transformation. They choose a parameterized class of such mappings and use a heuristic search algorithm to optimize the parameters to minimize the severity of the motion artifacts. To increase the speed of the optimization process they use a statistical image comparison technique that provides a quick approximate evaluation of each image transformation. They present the experimental results of the application of their registration system to mask-contrast pairs, for images acquired from a specially designed phantom, and for clinical images

UBVRIz LIGHT CURVES OF 51 TYPE II SUPERNOVAE

International Nuclear Information System (INIS)

Galbany, Lluis; Hamuy, Mario; Jaeger, Thomas de; Moraga, Tania; González-Gaitán, Santiago; Gutiérrez, Claudia P.; Phillips, Mark M.; Morrell, Nidia I.; Thomas-Osip, Joanna; Suntzeff, Nicholas B.; Maza, José; González, Luis; Antezana, Roberto; Wishnjewski, Marina; Krisciunas, Kevin; Krzeminski, Wojtek; McCarthy, Patrick; Anderson, Joseph P.; Stritzinger, Maximilian; Folatelli, Gastón

2016-01-01

We present a compilation of UBVRIz light curves of 51 type II supernovae discovered during the course of four different surveys during 1986–2003: the Cerro Tololo Supernova Survey, the Calán/Tololo Supernova Program (C and T), the Supernova Optical and Infrared Survey (SOIRS), and the Carnegie Type II Supernova Survey (CATS). The photometry is based on template-subtracted images to eliminate any potential host galaxy light contamination, and calibrated from foreground stars. This work presents these photometric data, studies the color evolution using different bands, and explores the relation between the magnitude at maximum brightness and the brightness decline parameter (s) from maximum light through the end of the recombination phase. This parameter is found to be shallower for redder bands and appears to have the best correlation in the B band. In addition, it also correlates with the plateau duration, being shorter (longer) for larger (smaller) s values

UBVRIz LIGHT CURVES OF 51 TYPE II SUPERNOVAE

Energy Technology Data Exchange (ETDEWEB)

Galbany, Lluis; Hamuy, Mario; Jaeger, Thomas de; Moraga, Tania; González-Gaitán, Santiago; Gutiérrez, Claudia P. [Millennium Institute of Astrophysics, Universidad de Chile (Chile); Phillips, Mark M.; Morrell, Nidia I.; Thomas-Osip, Joanna [Carnegie Observatories, Las Campanas Observatory, Casilla 60, La Serena (Chile); Suntzeff, Nicholas B. [Department of Physics and Astronomy, Texas A and M University, College Station, TX 77843 (United States); Maza, José; González, Luis; Antezana, Roberto; Wishnjewski, Marina [Departamento de Astronomía, Universidad de Chile, Camino El Observatorio 1515, Las Condes, Santiago (Chile); Krisciunas, Kevin [George P. and Cynthia Woods Mitchell Institute for Fundamental Physics and Astronomy, Texas A. and M. University, Department of Physics and Astronomy, 4242 TAMU, College Station, TX 77843 (United States); Krzeminski, Wojtek [N. Copernicus Astronomical Center, ul. Bartycka 18, 00-716 Warszawa (Poland); McCarthy, Patrick [The Observatories of the Carnegie Institution for Science, 813 Santa Barbara Street, Pasadena, CA 91101 (United States); Anderson, Joseph P. [European Southern Observatory, Alonso de Cordova 3107, Vitacura, Casilla 19001, Santiago (Chile); Stritzinger, Maximilian [Department of Physics and Astronomy, Aarhus University (Denmark); Folatelli, Gastón, E-mail: lgalbany@das.uchile.cl [Instituto de Astrofísica de La Plata (IALP, CONICET) (Argentina); and others

2016-02-15

We present a compilation of UBVRIz light curves of 51 type II supernovae discovered during the course of four different surveys during 1986–2003: the Cerro Tololo Supernova Survey, the Calán/Tololo Supernova Program (C and T), the Supernova Optical and Infrared Survey (SOIRS), and the Carnegie Type II Supernova Survey (CATS). The photometry is based on template-subtracted images to eliminate any potential host galaxy light contamination, and calibrated from foreground stars. This work presents these photometric data, studies the color evolution using different bands, and explores the relation between the magnitude at maximum brightness and the brightness decline parameter (s) from maximum light through the end of the recombination phase. This parameter is found to be shallower for redder bands and appears to have the best correlation in the B band. In addition, it also correlates with the plateau duration, being shorter (longer) for larger (smaller) s values.

The Role of Bone Subtraction Computed Tomographic Angiography in Determining Intracranial Aneurysms in Non-Traumatic Subarachnoid Hemorrhage

International Nuclear Information System (INIS)

Kayhan, Aysegul; Koc, Osman; Keskin, Suat; Keskin, Fatih

2014-01-01

The presence of blood in the subarachnoid space is an acute pathology with a serious risk of death and complications. The most common etiology (approximately 80%) is intracranial aneurysm. The aim of this study was to assess the role of bone subtracted computed tomographic angiography (BSCTA), a novel and noninvasive method for determining and characterizing intracranial aneurysms. Sixty consecutive patients with clinically suspected non-traumatic subarachnoid hemorrhage (SAH) were considered to enter the study. The subtraction quality was inadequate in ten patients; thus, they were excluded, leaving 50 patients (84.4%) in the study. Bone subtracted and non-subtracted 3D images were obtained from the BSCTA raw data sets. All images obtained by digital subtraction angiography (DSA), BSCTA, and computed tomographic angiography (CTA) were evaluated for the presence or absence of an aneurysm and the location, minimal sac diameter, and neck size ratio of the aneurysm. DSA was considered as the gold standard during the evaluation of the data. Of the 50 patients who participated in this study, 11 had no aneurysms as determined by both CTA and DSA. Examination of the remaining 39 patients revealed the presence of 51 aneurysms. While 3D-CTA could not detect six aneurysms that were located in the base of the skull, 3D-BSCTA easily detected them. Moreover, five aneurysms were only partially detected by 3D-CTA. According to this data, the sensitivity of 3D-BSCTA and 3D-CTA was calculated as 98% and 86.3%, respectively; the specificity was calculated as 100% and 90.9%, respectively, per aneurysm; and the sensitivity of 100% for 3D-BSCTA and 98% for 3D-CTA was achieved by using combined images with multi-planar reconstruction (MPR) and maximum intensity projection (MIP). BSCTA detected and characterized the aneurysms as well as DSA, and BSCTA and DSA gave concordant results in detecting aneurysms. BSCTA is easily accessible, less time consuming, and most importantly, a non

The Role of Bone Subtraction Computed Tomographic Angiography in Determining Intracranial Aneurysms in Non-Traumatic Subarachnoid Hemorrhage

Science.gov (United States)

Kayhan, Aysegul; Koc, Osman; Keskin, Suat; Keskin, Fatih

2014-01-01

Background: The presence of blood in the subarachnoid space is an acute pathology with a serious risk of death and complications. The most common etiology (approximately 80%) is intracranial aneurysm. Objectives: The aim of this study was to assess the role of bone subtracted computed tomographic angiography (BSCTA), a novel and noninvasive method for determining and characterizing intracranial aneurysms. Patients and Methods: Sixty consecutive patients with clinically suspected non-traumatic subarachnoid hemorrhage (SAH) were considered to enter the study. The subtraction quality was inadequate in ten patients; thus, they were excluded, leaving 50 patients (84.4%) in the study. Bone subtracted and non-subtracted 3D images were obtained from the BSCTA raw data sets. All images obtained by digital subtraction angiography (DSA), BSCTA, and computed tomographic angiography (CTA) were evaluated for the presence or absence of an aneurysm and the location, minimal sac diameter, and neck size ratio of the aneurysm. DSA was considered as the gold standard during the evaluation of the data. Results: Of the 50 patients who participated in this study, 11 had no aneurysms as determined by both CTA and DSA. Examination of the remaining 39 patients revealed the presence of 51 aneurysms. While 3D-CTA could not detect six aneurysms that were located in the base of the skull, 3D-BSCTA easily detected them. Moreover, five aneurysms were only partially detected by 3D-CTA. According to this data, the sensitivity of 3D-BSCTA and 3D-CTA was calculated as 98% and 86.3%, respectively; the specificity was calculated as 100% and 90.9%, respectively, per aneurysm; and the sensitivity of 100% for 3D-BSCTA and 98% for 3D-CTA was achieved by using combined images with multi-planar reconstruction (MPR) and maximum intensity projection (MIP). BSCTA detected and characterized the aneurysms as well as DSA, and BSCTA and DSA gave concordant results in detecting aneurysms. Conclusions: BSCTA is

The comparison of Tc99m-pertechnetate/mibi subtraction and double phase Tc99m-mibi techniques in parathyroid imaging

International Nuclear Information System (INIS)

Bilkay, Ue.; Erinc, R.; Karapolat, I.; Kumanlioglu, K.

2001-01-01

Experienced parathyroid surgeons can localize nearly %90-95 of the abnormal parathyroid glands with total thyroid bed exploration. For this reason, for the first surgical exploration preoperative imaging of the gland could be considered unnecessary. However, localization of the abnormal parathyroid tissue preoperatively could be beneficial in ectopic adenomas which consists %20 of all adenomas and also in shortening surgical procedure in single adenomas with the use of unilateral exploration. Re-exploration after an unsuccessful surgery is the most widely accepted indication for parathyroid imaging. Today, although Tc99m-MIBI is the accepted radionuclide with the advantages of giving better image quality with lower radiation dose over Tl-201, for imaging hyper functioning parathyroid tissue, there is no consensus on the ideal imaging protocol. Single-tracer double-phase imaging (STDP) and dual-tracer subtraction technique (Tc99m-pertechnetate/Tc99m-MIBI) (DTST) are proposed protocols using Tc99m-MIBI. The aim of this ongoing study is; to compare STDP imaging with DTST and to compare sensitivity of pinhole and high resolution parallel hole images in STDP protocol

On the difference between additive and subtractive QM/MM calculations

Science.gov (United States)

Cao, Lili; Ryde, Ulf

2018-04-01

The combined quantum mechanical (QM) and molecular mechanical (MM) approach (QM/MM) is a popular method to study reactions in biochemical macromolecules. Even if the general procedure of using QM for a small, but interesting part of the system and MM for the rest is common to all approaches, the details of the implementations vary extensively, especially the treatment of the interface between the two systems. For example, QM/MM can use either additive or subtractive schemes, of which the former is often said to be preferable, although the two schemes are often mixed up with mechanical and electrostatic embedding. In this article, we clarify the similarities and differences of the two approaches. We show that inherently, the two approaches should be identical and in practice require the same sets of parameters. However, the subtractive scheme provides an opportunity to correct errors introduced by the truncation of the QM system, i.e. the link atoms, but such corrections require additional MM parameters for the QM system. We describe and test three types of link-atom correction, viz. for van der Waals, electrostatic and bonded interactions. The calculations show that electrostatic and bonded link-atom corrections often give rise to problems in the geometries and energies. The van der Waals link-atom corrections are quite small and give results similar to a pure additive QM/MM scheme. Therefore, both approaches can be recommended.

On the Difference Between Additive and Subtractive QM/MM Calculations

Directory of Open Access Journals (Sweden)

Lili Cao

2018-04-01

Full Text Available The combined quantum mechanical (QM and molecular mechanical (MM approach (QM/MM is a popular method to study reactions in biochemical macromolecules. Even if the general procedure of using QM for a small, but interesting part of the system and MM for the rest is common to all approaches, the details of the implementations vary extensively, especially the treatment of the interface between the two systems. For example, QM/MM can use either additive or subtractive schemes, of which the former is often said to be preferable, although the two schemes are often mixed up with mechanical and electrostatic embedding. In this article, we clarify the similarities and differences of the two approaches. We show that inherently, the two approaches should be identical and in practice require the same sets of parameters. However, the subtractive scheme provides an opportunity to correct errors introduced by the truncation of the QM system, i.e., the link atoms, but such corrections require additional MM parameters for the QM system. We describe and test three types of link-atom correction, viz. for van der Waals, electrostatic, and bonded interactions. The calculations show that electrostatic and bonded link-atom corrections often give rise to problems in the geometries and energies. The van der Waals link-atom corrections are quite small and give results similar to a pure additive QM/MM scheme. Therefore, both approaches can be recommended.

The value of subtraction MRI in detection of amyloid-related imaging abnormalities with oedema or effusion in Alzheimer's patients. An interobserver study

International Nuclear Information System (INIS)

Martens, Roland M.; Bechten, Arianne; Ingala, Silvia; Schijndel, Ronald A. van; Machado, Vania B.; Jong, Marcus C. de; Sanchez, Esther; Wattjes, Mike P.; Purcell, Derk; Arrighi, Michael H.; Brashear, Robert H.; Barkhof, Frederik

2018-01-01

Immunotherapeutic treatments targeting amyloid-β plaques in Alzheimer's disease (AD) are associated with the presence of amyloid-related imaging abnormalities with oedema or effusion (ARIA-E), whose detection and classification is crucial to evaluate subjects enrolled in clinical trials. To investigate the applicability of subtraction MRI in the ARIA-E detection using an established ARIA-E-rating scale. We included 75 AD patients receiving bapineuzumab treatment, including 29 ARIA-E cases. Five neuroradiologists rated their brain MRI-scans with and without subtraction images. The accuracy of evaluating the presence of ARIA-E, intraclass correlation coefficient (ICC) and specific agreement was calculated. Subtraction resulted in higher sensitivity (0.966) and lower specificity (0.970) than native images (0.959, 0.991, respectively). Individual rater detection was excellent. ICC scores ranged from excellent to good, except for gyral swelling (moderate). Excellent negative and good positive specific agreement among all ARIA-E imaging features was reported in both groups. Combining sulcal hyperintensity and gyral swelling significantly increased positive agreement for subtraction images. Subtraction MRI has potential as a visual aid increasing the sensitivity of ARIA-E assessment. However, in order to improve its usefulness isotropic acquisition and enhanced training are required. The ARIA-E rating scale may benefit from combining sulcal hyperintensity and swelling. (orig.)

The value of subtraction MRI in detection of amyloid-related imaging abnormalities with oedema or effusion in Alzheimer's patients. An interobserver study

Energy Technology Data Exchange (ETDEWEB)

Martens, Roland M.; Bechten, Arianne; Ingala, Silvia; Schijndel, Ronald A. van; Machado, Vania B.; Jong, Marcus C. de; Sanchez, Esther; Wattjes, Mike P. [VU University Medical Center, Department of Radiology and Nuclear Medicine, Neuroscience Campus Amsterdam (Netherlands); Purcell, Derk [California Pacific Medical Center, Department of Radiology, San Francisco, CA (United States); BioClinica Inc, Newark, CA (United States); Arrighi, Michael H.; Brashear, Robert H. [Janssen Alzheimer Immunotherapy Research and Development, LLC, South San Francisco, CA (United States); Barkhof, Frederik [VU University Medical Center, Department of Radiology and Nuclear Medicine, Neuroscience Campus Amsterdam (Netherlands); University College London, Institutes of Neurology and Healthcare Engineering, London (United Kingdom)

2018-03-15

Immunotherapeutic treatments targeting amyloid-β plaques in Alzheimer's disease (AD) are associated with the presence of amyloid-related imaging abnormalities with oedema or effusion (ARIA-E), whose detection and classification is crucial to evaluate subjects enrolled in clinical trials. To investigate the applicability of subtraction MRI in the ARIA-E detection using an established ARIA-E-rating scale. We included 75 AD patients receiving bapineuzumab treatment, including 29 ARIA-E cases. Five neuroradiologists rated their brain MRI-scans with and without subtraction images. The accuracy of evaluating the presence of ARIA-E, intraclass correlation coefficient (ICC) and specific agreement was calculated. Subtraction resulted in higher sensitivity (0.966) and lower specificity (0.970) than native images (0.959, 0.991, respectively). Individual rater detection was excellent. ICC scores ranged from excellent to good, except for gyral swelling (moderate). Excellent negative and good positive specific agreement among all ARIA-E imaging features was reported in both groups. Combining sulcal hyperintensity and gyral swelling significantly increased positive agreement for subtraction images. Subtraction MRI has potential as a visual aid increasing the sensitivity of ARIA-E assessment. However, in order to improve its usefulness isotropic acquisition and enhanced training are required. The ARIA-E rating scale may benefit from combining sulcal hyperintensity and swelling. (orig.)

Thallium-201 chloride dynamic analysis using thallium-201 chloride and sodium iodide-131 thyroid subtraction scintigraphy

Energy Technology Data Exchange (ETDEWEB)

Morimoto, Setsuo; Hiraki, Yoshio; Togami, Izumi [Okayama Univ. (Japan). School of Medicine

1984-10-01

The mechanism of /sup 201/Tl chloride accumulation is unclear in thyroid gland and thyroid tumor. This report examines 108 patients that received thyroid scintigraphy examinations with both /sup 201/Tl chloride and sodium /sup 131/I. The patients were diagnosed clinically and histologically whenever possible. The ROI were obtained by subtraction imaging with both isotopes and by subtraction positive and negative areas of imaging. Dynamic curves were obtained for /sup 201/Tl chloride per square unit of each ROI. The dynamic curve in the radioiodide-accumulated area was examined. The data indicate that the clearance rate of /sup 201/Tl chloride (T/sub 15/) was correlated with the sodium /sup 131/I uptake rate at 24 h (r=0.70).

Subtraction radiography and computer assisted densitometric analyses of standardized radiographs. A comparison study with /sup 125/I absorptiometry

Energy Technology Data Exchange (ETDEWEB)

Ortmann, L.F.; Dunford, R.; McHenry, K.; Hausmann, E.

1985-01-01

A standardized radiographic series of incrementally increasing alveolar crestal defects in skulls were subjected to analyses by subtraction radiography and computer assisted quantitative densitometric analysis. Subjects were able to detect change using subtraction radiography in alveolar bone defects with bone loss in the range of 1-5 percent as measured by /sup 125/I absorptiometry. Quantitative densitometric analyses utilizing radiographic pairs adjusted for differences in contrast (gamma corrected) can be used to follow longitudinal changes at a particular alveolar bone site. Such measurements correlate with change observed by /sup 125/I absorptiometry (r=0.82-0.94). (author).

Maximal Abelian and Curci-Ferrari gauges in momentum subtraction at three loops

Science.gov (United States)

Bell, J. M.; Gracey, J. A.

2015-12-01

The vertex structure of QCD fixed in the maximal Abelian gauge (MAG) and Curci-Ferrari gauge is analyzed at two loops at the fully symmetric point for the 3-point functions corresponding to the three momentum subtraction (MOM) renormalization schemes. Consequently, the three-loop renormalization group functions are determined for each of these three schemes in each gauge using properties of the renormalization group equation.

Pelvic digital subtraction catheter angiography-Are routine oblique projections necessary?

International Nuclear Information System (INIS)

Rane, Neil; Imam, Atique; Foley, Peter; Timmons, Grace; Uberoi, Raman

2011-01-01

The oblique projection is used widely in imaging of the lower vascular tree. Much of the evidence justifying the oblique projection is anecdotal. This study compares the sensitivity of the anteroposterior (AP) projection alone in lower limb vascular catheter angiography to that combined with the oblique projection. 110 digitally subtracted angiograms were analysed initially on AP and subsequently on oblique views. Oblique imaging increases confidence, demonstrates stenoses not seen on AP and changes the diagnosis. This supports the use of the oblique projection in lower limb vascular interventional imaging.

Multinuclide digital subtraction imaging in symptomatic prostnetic joints

International Nuclear Information System (INIS)

Chafetz, N.; Hattner, R.S.; Ruarke, W.C.; Helms, C.A.; Genant, H.K.; Murray, W.R.

1985-01-01

One hundred eleven patients with symptomatic prosthetic joints (86 hips, 23 knees, and two shoulders) were evaluated for prosthetic loosening and infection by combined technetium-99m-MDP/gallium-67 digital subtraction imaging. Clinical correlation was based on the assessment of loosening and bacterial cultures obtained at the time of surgery in 54 patients, joint aspiration cultures obtained in 37 patients, and long-term clinical follow-up for greater than 1.5 years in an additional 15 patients. Results revealed an 80-90% predictive value of a positive test for loosening, and a 95% predictive value of a negative test for infection. However, because of the low sensitivities and specificities observed, this approach to the evaluation of symptomatic prosthetic joints does not seem cost effective

THE APPLICATION OF CONTINUOUS WAVELET TRANSFORM BASED FOREGROUND SUBTRACTION METHOD IN 21 cm SKY SURVEYS

International Nuclear Information System (INIS)

Gu Junhua; Xu Haiguang; Wang Jingying; Chen Wen; An Tao

2013-01-01

We propose a continuous wavelet transform based non-parametric foreground subtraction method for the detection of redshifted 21 cm signal from the epoch of reionization. This method works based on the assumption that the foreground spectra are smooth in frequency domain, while the 21 cm signal spectrum is full of saw-tooth-like structures, thus their characteristic scales are significantly different. We can distinguish them in the wavelet coefficient space easily and perform the foreground subtraction. Compared with the traditional spectral fitting based method, our method is more tolerant to complex foregrounds. Furthermore, we also find that when the instrument has uncorrected response error, our method can also work significantly better than the spectral fitting based method. Our method can obtain similar results with the Wp smoothing method, which is also a non-parametric method, but our method consumes much less computing time

A subtractive approach to interior intrusion detection system design

International Nuclear Information System (INIS)

Sons, R.J.; Graham, R.H. Jr.

1986-01-01

This paper discusses the subtractive approach to interior intrusion detection system design which assumes that all sensors are viable candidates until they are subjected to the constraints imposed by a particular facility. The constraints are determined by a sequence of questions concerning parameters such as threat definition, facility description and operation, environment, assets to be protected, security system capabilities, and cost. As a result of the questioning, some sensors will be eliminated from the candidate list, and the ''best'' set of sensors for the facility will remain. This form of questioning could be incorporated into an expert system aiding future intrusion detection system designs

Intra-arterial digital subtraction angiography of the carotid arteries

International Nuclear Information System (INIS)

Nakstad, P.; Bakke, S.J.; Kjartansson, O.; Nyhus, S.

1986-01-01

A cross-over test in intra-arterial digital subtraction angiography (IADSA) of the carotid arteries was performed in 50 patients to evaluate image quality and side-effects with iohexol and metrizoate injected at concentrations of 100 mg I/ml by hand. The image quality was excellent or good in all cases. Although the severity and the frequency of side-effects were higher with metrizoate, both contrast media were suitable for IADSA at this low concentration. No complications were seen. It was assumed that the risk with IADSA was less than that of conventional-selectivity and with small amounts of contrast media, as in this study. (orig.)

Digital subtraction angiography - a new approach to brain death determination in the newborn

International Nuclear Information System (INIS)

Albertini, A.; Schonfeld, S.; Hiatt, M.; Hegyi, T.

1993-01-01

The diagnosis of brain death in the newborn infants is elusive and often difficult. The lack of cerebral blood flow has become an identified criterion for loss of cerebral function. The diagnosis can be obtained by the technique of digital subtraction angiography, which is presented in two case reports demonstrating the utility of this technique. (orig.)

Real-time digital X-ray subtraction imaging

International Nuclear Information System (INIS)

Mistretta, C.A.; Kruger, R.A.; Houk, T.L.

1979-01-01

A diagnostic anatomical X-ray apparatus comprising a converter and a television camera for converting an X-ray image of a subject into a series of television fields of video signals is described in detail. A digital memory system stores and integrates the video signals over a time interval corresponding to a plurality of successive television fields. The integrated video signals are recovered from storage and fed to a digital or analogue subtractor, the resulting output being displayed on a television monitor. Thus the display represents on-going changes in the anatomical X-ray image. In a modification, successive groups of fields are stored and integrated in three memories, cyclically, and subtractions are performed between successive pieces of integrated signals to provide a display of successive alterations in the X-ray image. For investigations of the heart, the integrating interval should be of the order of one cardiac cycle. (author)

Thallium-technetium-subtraction scintigraphy in secondary hyperparathyroidism

International Nuclear Information System (INIS)

Adalet, I.; Hawkins, T.; Clark, F.; Wilkinson, R.

1994-01-01

Between 1983 and 1992 thallium-technetium subtraction scintigraphy (TTS) was performed on 74 patients with clinical and biochemical evidence of hyperparathyroidism. Twenty-five of the 53 investigations since 1988 were conducted on patients with renal failure with a suspicion of secondary hyperparathyroidism. In a retrospective study we have evaluated radioisotope scintigraphy for patients with adenoma and for renal failure patients with possible parathyroid hyperplasia. Thirty of 74 patients underwent neck exploration. Scintigraphy detected 17 of 24 parathyroid adenomas (sensitivity 71%). In contrast, in six renal patients who came to operation, scintigraphy localised only 5 of 20 hyperplastic parathyroid glands (sensitivity 25%) and in one renal patient we localised a parathyroid adenoma. A review of the literature shows low detection rates for hyperplasia by TTS to be a common observation. Based on these findings a rational approach is offered for parathyroid localisation in renal patients prior to neck exploration. (orig.)

Synthesis, spectral and thermal studies of pyridyl adducts of Zn(II) and Cd(II) dithiocarbamates, and their use as single source precursors for ZnS and CdS nanoparticles.

Science.gov (United States)

Onwudiwe, Damian C; Strydom, Christien A; Oluwafemi, Oluwatobi S; Hosten, Eric; Jordaan, Anine

2014-06-21

The synthesis, spectroscopic characterisation, and thermal studies of pyridyl adducts of Zn(II) and Cd(II) complexes of N-ethyl-N-phenyl dithiocarbamate, represented as [ZnL2py] and [CdL2py2], are reported. Single-crystal X-ray structural analysis of the Zn compound showed that it is five-coordinate with four sulphurs from dithiocarbamate and one nitrogen from pyridine in a distorted square pyramidal geometry. The thermogravimetric studies indicate that the zinc and cadmium compounds undergo fast weight loss, and the temperature at maximum rate of decomposition is at 277 °C and 265 °C respectively, to give the metal (Zn or Cd) sulphide residues. These compounds were used as single molecule precursors to produce nanocrystalline MS (M = Zn, Cd) after thermolysis in hexadecylamine. The morphological and optical properties of the resulting MS nanocrystallites were investigated using transmission electron microscopy (TEM), scanning electron microscopy (SEM), UV-Vis absorption and photoluminescence (PL) spectroscopy, and powdered X-ray diffraction (XRD). By varying the growth time, the temporal evolution of the optical properties and morphology of the nanocrystals were investigated.

N -jettiness subtractions for g g →H at subleading power

Science.gov (United States)

Moult, Ian; Rothen, Lorena; Stewart, Iain W.; Tackmann, Frank J.; Zhu, Hua Xing

2018-01-01

N -jettiness subtractions provide a general approach for performing fully-differential next-to-next-to-leading order (NNLO) calculations. Since they are based on the physical resolution variable N -jettiness, TN , subleading power corrections in τ =TN/Q , with Q a hard interaction scale, can also be systematically computed. We study the structure of power corrections for 0-jettiness, T0, for the g g →H process. Using the soft-collinear effective theory we analytically compute the leading power corrections αsτ ln τ and αs2τ ln3τ (finding partial agreement with a previous result in the literature), and perform a detailed numerical study of the power corrections in the g g , g q , and q q ¯ channels. This includes a numerical extraction of the αsτ and αs2τ ln2τ corrections, and a study of the dependence on the T0 definition. Including such power suppressed logarithms significantly reduces the size of missing power corrections, and hence improves the numerical efficiency of the subtraction method. Having a more detailed understanding of the power corrections for both q q ¯ and g g initiated processes also provides insight into their universality, and hence their behavior in more complicated processes where they have not yet been analytically calculated.

Use of signal subtraction methods in ESR dating of burned flint

International Nuclear Information System (INIS)

Porat, Naomi; Schwarcz, H.P.

1991-01-01

Geological samples of chert display some of the characteristics of electron spin resonance (ESR) signals of quartz. When chert is heated in a fireplace, most of these signals are annealed. The signals grow again in fire-heated chert buried in archaeological sites, as a result of internal and external radiation doses. The date of the heating event can be determined from the acquired dose (AD) and the dose rate. The E' and Al signals are best suited for dating. Although many cherts, when heated to a sufficient temperature, acquire a carbon radical (C) signal that largely obscures the E' signal, it can be subtracted from digitized spectra. The E' signal also appears to saturate at relatively low doses, restricting the time range of dating to between 200 and 600 ka, depending on the dose rates. The Al signal shows no saturation, but is also interfered with by organic signals, present in burnt and unburned flint. These can also be subtracted to reveal the ''pure'' Al signal. Applying the E' signal to date flint from Yabroud, we obtain an age between 100 and 125 ka, while both thermoluminescence (TL) dating of the flint and ESR dating of tooth enamel give 195 and 225 ka, respectively; the discrepancy may be due to an overestimate of the α-efficiency. At Nahr Ibrahim, the age (c. 80 ka) is consistent with archaeological estimates. (author)

The parallel-sequential field subtraction technique for coherent nonlinear ultrasonic imaging

Science.gov (United States)

Cheng, Jingwei; Potter, Jack N.; Drinkwater, Bruce W.

2018-06-01

Nonlinear imaging techniques have recently emerged which have the potential to detect cracks at a much earlier stage than was previously possible and have sensitivity to partially closed defects. This study explores a coherent imaging technique based on the subtraction of two modes of focusing: parallel, in which the elements are fired together with a delay law and sequential, in which elements are fired independently. In the parallel focusing a high intensity ultrasonic beam is formed in the specimen at the focal point. However, in sequential focusing only low intensity signals from individual elements enter the sample and the full matrix of transmit-receive signals is recorded and post-processed to form an image. Under linear elastic assumptions, both parallel and sequential images are expected to be identical. Here we measure the difference between these images and use this to characterise the nonlinearity of small closed fatigue cracks. In particular we monitor the change in relative phase and amplitude at the fundamental frequencies for each focal point and use this nonlinear coherent imaging metric to form images of the spatial distribution of nonlinearity. The results suggest the subtracted image can suppress linear features (e.g. back wall or large scatters) effectively when instrumentation noise compensation in applied, thereby allowing damage to be detected at an early stage (c. 15% of fatigue life) and reliably quantified in later fatigue life.

Crowded Field Photometry and Moving Object Detection with Optimal Image Subtraction

Science.gov (United States)

Lee, Austin A. T.; Scheulen, F.; Sauro, C. M.; McMahon, C. T.; Berry, S. J.; Robinson, C. H.; Buie, M. W.; Little, P.

2010-05-01

High precision photometry and moving object detection are essential in the study of Pluto and the Kuiper Belt. In particular, the New Horizons mission would benefit from an accurate and fast method of performing image subtraction to locate faint Kuiper Belt Objects (KBO) among large data sets. The optimal image subtraction (OIS) algorithm was optimized for IDL to decrease execution time by a factor of about 140 from a previous implementation (Miller 2008, PASP, 120, 449). In addition, a powerful image transformation and interpolation routine was written to provide OIS with well-aligned input images using astrometric fit data. The first half of this project is complete including the code optimization and the alignment routine. The second half of the project is focused on using these tools to search a 5 x 10 degree search area to find KBOs for possible targets for the New Horizons mission. We will present examples of how these tools work and along with resulting Pluto photometry and KBO target lists. The optimized OIS and transformation routines are available in Marc Buie's IDL library at http://www.boulder.swri.edu/ buie/idl/ as ois.pro and dewarp.pro. This project was conducted for Harvey Mudd College's Clinic Program with financial support from the NASA Planetary Astronomy Program grant number NNX09AB43G.

Use of subvoxel registration and subtraction to improve demonstration of contrast enhancement in MRI of the brain

International Nuclear Information System (INIS)

Curati, W.L.; Williams, E.J.; Oatridge, A.; Hajnal, J.V.; Saeed, N.; Bydder, G.M.

1996-01-01

To assess the potential of registration of images before and after contrast medium for improving the demonstration of contrast enhancement, we compared conventional 2 D T 1-weighted spin-echo images with precisely registered 3 D volume images and subtraction images derived from them in 2 normal subjects and 30 patients with a variety of brain disease. The volume images were registered to subvoxel accuracy using a rigid body translation and rotation, sinc interpolation and a least-squares fit; subtraction images were obtained from these. Normal contrast enhancement was demonstrated better with positionally registered volume and subtraction images than with conventional images in the meninges, ependyma, diploic veins, scalp, skin, orbit and sinuses. Abnormal enhancement was seen better in meningeal disease, multiple sclerosis and tumours as well as on follow-up studies. Subvoxel registration of images before and after contrast medium may be of considerable value in the recognition of contrast enhancement where there are small changes, or where the changes affect tissues with high or low baseline signal values. The technique also appears likely to be of value in demonstrating contrast enhancement in tissues at inferfaces and at other areas of complex anatomy, and in follow-up studies. (orig.). With 4 figs., 4 tabs

Study of GABAergic extra-synaptic tonic inhibition in single neurons and neural populations by traversing neural scales: application to propofol-induced anaesthesia.

Science.gov (United States)

Hutt, Axel; Buhry, Laure

2014-12-01

Anaesthetic agents are known to affect extra-synaptic GABAergic receptors, which induce tonic inhibitory currents. Since these receptors are very sensitive to small concentrations of agents, they are supposed to play an important role in the underlying neural mechanism of general anaesthesia. Moreover anaesthetic agents modulate the encephalographic activity (EEG) of subjects and hence show an effect on neural populations. To understand better the tonic inhibition effect in single neurons on neural populations and hence how it affects the EEG, the work considers single neurons and neural populations in a steady-state and studies numerically and analytically the modulation of their firing rate and nonlinear gain with respect to different levels of tonic inhibition. We consider populations of both type-I (Leaky Integrate-and-Fire model) and type-II (Morris-Lecar model) neurons. To bridge the single neuron description to the population description analytically, a recently proposed statistical approach is employed which allows to derive new analytical expressions for the population firing rate for type-I neurons. In addition, the work shows the derivation of a novel transfer function for type-I neurons as considered in neural mass models and studies briefly the interaction of synaptic and extra-synaptic inhibition. We reveal a strong subtractive and divisive effect of tonic inhibition in type-I neurons, i.e. a shift of the firing rate to higher excitation levels accompanied by a change of the nonlinear gain. Tonic inhibition shortens the excitation window of type-II neurons and their populations while maintaining the nonlinear gain. The gained results are interpreted in the context of recent experimental findings under propofol-induced anaesthesia.

A feasibility study of projection-based energy weighting based on a photon-counting detector in contrast-enhanced digital subtraction mammography: a simulation study

International Nuclear Information System (INIS)

Choi, Sunghoon; Lee, Seungwan; Choi, Yuna; Kim, Heejoung

2014-01-01

Contrast media, such as iodine and gadolinium, are generally used in digital subtraction mammography to enhance the contrast between target and background materials. In digital subtraction mammography, where one image (with contrast medium) is subtracted from another (anatomical background) to facilitate visualization of the tumor structure, tumors can be more easily distinguished after the injection of a contrast medium. In order to have more an effective method to increase the contrast-to-noise ratio (CNR), we applied a projection-based energy-weighting method. The purpose of this study is to demonstrate the feasibility of using the projection-based energy-weighting method in digital subtraction mammography. Unlike some other previous studies, we applied the projection-based energy-weighting method to more practical mammography conditions by using the Monte Carlo method to simulate four different iodine solutions embedded in a breast phantom comprised of 50% adipose and 50% glandular tissues. We also considered an optimal tube voltage and anode/filter combination in digital iodine contrast media mammography in order to maximize the figure-of-merit (FOM). The simulated source energy was from 20 to 45 keV to prevent electronic noise and include the k-edge energy of iodine (33.2 keV). The results showed that the projection-based energy-weighting improved the CNR by factors of 1.05 - 1.86 compared to the conventionally integrated images. Consequently, the CNR of digital subtraction mammography images can be improved by using projection-based energy-weighting with photon-counting detectors.

A feasibility study of projection-based energy weighting based on a photon-counting detector in contrast-enhanced digital subtraction mammography: a simulation study

Energy Technology Data Exchange (ETDEWEB)

Choi, Sunghoon; Lee, Seungwan; Choi, Yuna; Kim, Heejoung [Yonsei University, Wonju (Korea, Republic of)

2014-06-15

Contrast media, such as iodine and gadolinium, are generally used in digital subtraction mammography to enhance the contrast between target and background materials. In digital subtraction mammography, where one image (with contrast medium) is subtracted from another (anatomical background) to facilitate visualization of the tumor structure, tumors can be more easily distinguished after the injection of a contrast medium. In order to have more an effective method to increase the contrast-to-noise ratio (CNR), we applied a projection-based energy-weighting method. The purpose of this study is to demonstrate the feasibility of using the projection-based energy-weighting method in digital subtraction mammography. Unlike some other previous studies, we applied the projection-based energy-weighting method to more practical mammography conditions by using the Monte Carlo method to simulate four different iodine solutions embedded in a breast phantom comprised of 50% adipose and 50% glandular tissues. We also considered an optimal tube voltage and anode/filter combination in digital iodine contrast media mammography in order to maximize the figure-of-merit (FOM). The simulated source energy was from 20 to 45 keV to prevent electronic noise and include the k-edge energy of iodine (33.2 keV). The results showed that the projection-based energy-weighting improved the CNR by factors of 1.05 - 1.86 compared to the conventionally integrated images. Consequently, the CNR of digital subtraction mammography images can be improved by using projection-based energy-weighting with photon-counting detectors.

Evaluation of left ventricular function by digital subtraction angiography

International Nuclear Information System (INIS)

Kuribayashi, Sachio; Ootaki, Makoto; Matsuyama, Seiya; Kanemoto, Nariaki; Furuya, Hideo

1985-01-01

Effects of contrast medium doses on left ventriculographic images using intravenous digital subtraction angiography (IVDSA-LVG) were assessed. The validity of IVDSA-LVG in evaluating ejection fraction (FF) and left ventricular regional wall motion was determined by comparison with conventional left ventriculography using direct injection (direct LVG). The advantages of left ventriculography using intraarterial subtraction angiography (IADSA-LVG) performed by injecting small doses of contrast media directly into the left ventricle were stressed. 1. To assess the effects of doses of contrast media on IVDSA-LVG, 10, 20, and 30 ml Urografin-76 were injected into the superior vena cava in 16 patients, and the resulting images were compared in each patient. With only 10 ml contrast medium, left ventricular opacification was fairly good, and regional wall motion was evaluated in many cases, but 30 ml were needed to calculate ventricular volume and EF. 2. To determine the validity of IVDSA-LVG in evaluating EF and regional wall motion, we compared IVDSA-LVG using 30 ml of contrast medium with direct LVG in 18 patients. There was a good correlation between the two methods in determining EF (r = 0.877), and 90 % of the interpretations of regional wall motion were in agreement by the two methods. IVDSA-LVG was useful and accurate in evaluating EF and regional wall motion of the left ventricle. 3. IADSA-LVG was performed for five patients, and good quality images were obtained in many cases, even with relatively small doses (10 ml) of contrast media. These results suggested that this method may be used in cases with impaired LV function, to avoid hemodynamic derangement induced by conventional direct LVG using large doses of contrast medium. (author)

Improved MDCT monitoring of pelvic myeloma bone disease through the use of a novel longitudinal bone subtraction post-processing algorithm

Energy Technology Data Exchange (ETDEWEB)

Horger, Marius; Thaiss, Wolfgang M.; Nikolaou, Konstantin; Kloth, Christopher [Eberhard-Karls-University Tuebingen, Department of Diagnostic and Interventional Radiology, Tuebingen (Germany); Ditt, Hendrik [Sector Imaging and Interventional Radiology, Siemens AG Healthcare, Forchheim (Germany); Weisel, Katja [Eberhard-Karls-University Tuebingen, Department of Internal Medicine II, Tuebingen (Germany); Fritz, Jan [Johns Hopkins University School of Medcine, Russell H. Morgan Department of Radiology and Radiological Science, Baltimore, MD (United States); Liao, Shu [Siemens Medical Solutions, Malvern, PA (United States)

2017-07-15

To evaluate the diagnostic performance of a novel CT post-processing software that generates subtraction maps of baseline and follow-up CT examinations in the course of myeloma bone lesions. This study included 61 consecutive myeloma patients who underwent repeated whole-body reduced-dose MDCT at our institution between November 2013 and June 2015. CT subtraction maps classified a progressive disease (PD) vs. stable disease (SD)/remission. Bone subtraction maps (BSMs) only and in combination with 1-mm (BSM+) source images were compared with 5-mm axial/MPR scans. Haematological response categories at follow-up were: complete remission (n = 9), very good partial remission (n = 2), partial remission (n = 17) and SDh (n = 19) vs. PDh (n = 14). Five-millimetre CT scan yielded PD (n = 14) and SD/remission (n = 47) whereas bone subtraction + 1-mm axial scans (BSM+) reading resulted in PD (n = 18) and SD/remission (n = 43). Sensitivity/ specificity/accuracy for 5-mm/1-mm/BSM(alone)/BSM + in ''lesion-by-lesion'' reading was 89.4 %/98.9 %/98.3 %/ 99.5 %; 69.1 %/96.9 %/72 %/92.1 % and 83.8 %/98.4 %/92.1 %/98.3 %, respectively. The use of BSM+ resulted in a change of response classification in 9.8 % patients (n = 6) from SD to PD. BSM reading is more accurate for monitoring myeloma compared to axial scans whereas BSM+ yields similar results with 1-mm reading (gold standard) but by significantly reduced reading time. (orig.)

Improved MDCT monitoring of pelvic myeloma bone disease through the use of a novel longitudinal bone subtraction post-processing algorithm

International Nuclear Information System (INIS)

Horger, Marius; Thaiss, Wolfgang M.; Nikolaou, Konstantin; Kloth, Christopher; Ditt, Hendrik; Weisel, Katja; Fritz, Jan; Liao, Shu

2017-01-01

To evaluate the diagnostic performance of a novel CT post-processing software that generates subtraction maps of baseline and follow-up CT examinations in the course of myeloma bone lesions. This study included 61 consecutive myeloma patients who underwent repeated whole-body reduced-dose MDCT at our institution between November 2013 and June 2015. CT subtraction maps classified a progressive disease (PD) vs. stable disease (SD)/remission. Bone subtraction maps (BSMs) only and in combination with 1-mm (BSM+) source images were compared with 5-mm axial/MPR scans. Haematological response categories at follow-up were: complete remission (n = 9), very good partial remission (n = 2), partial remission (n = 17) and SDh (n = 19) vs. PDh (n = 14). Five-millimetre CT scan yielded PD (n = 14) and SD/remission (n = 47) whereas bone subtraction + 1-mm axial scans (BSM+) reading resulted in PD (n = 18) and SD/remission (n = 43). Sensitivity/ specificity/accuracy for 5-mm/1-mm/BSM(alone)/BSM + in ''lesion-by-lesion'' reading was 89.4 %/98.9 %/98.3 %/ 99.5 %; 69.1 %/96.9 %/72 %/92.1 % and 83.8 %/98.4 %/92.1 %/98.3 %, respectively. The use of BSM+ resulted in a change of response classification in 9.8 % patients (n = 6) from SD to PD. BSM reading is more accurate for monitoring myeloma compared to axial scans whereas BSM+ yields similar results with 1-mm reading (gold standard) but by significantly reduced reading time. (orig.)

Evaluation and quality control of digital subtraction angiography systems

International Nuclear Information System (INIS)

Louisot, P.

1986-04-01

After reviewing the development of systems used in angiography, we rewind the medical interest and describe the steps of an angiographic examination. The following chapter is dedicated to the techniques used for the digitalization of video images. The components of the system involved in the image acquisition are thoroughly investigated in chapter 4. Then, we analyse the capabilities of the machines available in France in 1985. Chapter 6 is devoted to the criteria of quality in digital imaging. In order to assign qualitative values to the above criteria, we design a control procedure which is described in chapter 7. The procedure thus allows the estimate of the physical performances of angiographic digital subtraction systems [fr

A Theoretical and Experimental Study of the Subtraction of Two Scintigraphic Images - As Applied to Visualization of the Pancreas; Etude Theorique et Experimentale de la Soustraction de Deux Images Scintigraphiques

Energy Technology Data Exchange (ETDEWEB)

Desgrez, A.; Razafindramamba, V.; Saint-Laurent, J. de; Kellershohn, C. [CEA, Service Hospitalier Frederic Joliot, Orsay (France)

1969-05-15

Some scintigraphic studies are limited because the tissue being depicted is not selective with respect to the radioactive product available. For example, the radioactivity of the circulating blood interferes with mercury scanning of bucco-pharyngeal tumours. Scintigraphy of the pancreas is likewise impeded by localization of selenomethionine in the liver. Similarly, certain types of liver incorporation impair the visualization of insufficiency in the right kidney. One solution to this problem is to use two different labelled compounds to produce two images and then subtract one from the other so as to separate out the tissue to be depicted. The paper deals with the various problems involved in such subtraction. For example, exact spatial coincidence ofthedata to be subtracted can be ensured only by simultaneous recording of the two images; aconsecutive recording, even if it is fast, may be detrimental. The operation often consists in a double technique: suppression of the unwanted tissue by subtraction and amplification of the contrast between the tissue under investigation and residual background noise. These two operations, subtraction and amplification, relate to variable magnitudes; the resolution of the final image is thus a function of certain statistical parameters, which are also discussed. In studies carried out on the pancreas, attention is paid to the respective advantages and conditions of spectrometric separation of the various products which can be used for subtraction; the value of labelled rose bengal, which can also be used for eliminating certain intestinal loops, is stressed. A description is given of two types of apparatus which can be used in making the subtraction. The first and cheaper device involves storing the data obtained on four-track magnetic tape; the second and more rapid method utilizes the memory of a 4096-channel analyser. With both of these devices it is possible to make several subtractions during a single examination and the

Diffraction, chopping, and background subtraction for LDR

Science.gov (United States)

Wright, Edward L.

1988-01-01

The Large Deployable Reflector (LDR) will be an extremely sensitive infrared telescope if the noise due to the photons in the large thermal background is the only limiting factor. For observations with a 3 arcsec aperture in a broadband at 100 micrometers, a 20-meter LDR will emit 10(exp 12) per second, while the photon noise limited sensitivity in a deep survey observation will be 3,000 photons per second. Thus the background subtraction has to work at the 1 part per billion level. Very small amounts of scattered or diffracted energy can be significant if they are modulated by the chopper. The results are presented for 1-D and 2-D diffraction calculations for the lightweight, low-cost LDR concept that uses an active chopping quaternary to correct the wavefront errors introduced by the primary. Fourier transforms were used to evaluate the diffraction of 1 mm waves through this system. Unbalanced signals due to dust and thermal gradients were also studied.

Alpha efficiency under TL and OSL - A subtraction technique using OSL and TL to detect artificial irradiation

International Nuclear Information System (INIS)

Zink, A.J.C.; Dabis, S.; Porto, E.; Castaing, J.

2010-01-01

With the development of thermoluminescence (TL) and optically stimulated luminescence (OSL) to determine the authenticity of old ceramics, forgers use artificial irradiation by gamma ray to age modern productions. Besides fraudulent action, objects can be exposed to various sources of X-rays (e.g. radiography, security control at airports). For all these reasons, the determination of artificial irradiation is an important topic for dating art objects. The main technique to identify artificial irradiations is the subtraction technique. It is based on the fact that alpha efficiency varies according to the luminescence technique (fine grain, coarse grains, predose, OSL). Having observed a rather significant difference of alpha efficiency for TL and OSL, we propose a new subtraction technique using OSL and TL of fine grains.

A simple proof of renormalization group equation in the minimal subtraction scheme

International Nuclear Information System (INIS)

Chetyrkin, K.G.

1989-04-01

We give a simple combinatorial proof of the renormalization group equation in the minimal subtraction scheme. Being mathematically rigorous, the proof avoids both the notorious complexity of techniques using parametric representations of Feynman diagrams and heuristic arguments of usual ''proofs'' calling up bare fields living in the space-time of complex dimension. It also copes easily with the general case of Green functions of arbitrary number of composite fields. (author). 24 refs

Intraarterial digital subtraction angiography in bronchogenic carcinoma treated with bronchial artery infusion

International Nuclear Information System (INIS)

Gao-Jun Teng; Xi-Lei Chai; Guang-Ru Gao; Cheng-Fong Chu; Xian-Guang Zhou; Zhu-Yi Zhang; Ru-Li Xiang

1991-01-01

Intra-arterial digital subtraction angiography (IADSA) has been used with advantage for control of the results of bronchial artery infusion of drugs for primarily unresectable bronchogenic carcinoma. The IADSA has been performed as road mapping prior to therapy. Drug treatment has been performed with 4 different regimes, depending on tumour type. Debulking and in some cases complete healing are the results, which are superior to other reported treatments. (author). 7 refs.; 4 figs.; 3 tabs

Developments in dual-energy, single-exposure chest radiography

International Nuclear Information System (INIS)

Ho Jungtsuoe.

1990-01-01

Conventional chest radiography (CCR), the most commonly performed technique for the diagnosis of lung cancer, does not detect a high percentage of these tumors. One reason for errors is the overlap of tumor image with bone image in a chest radiograph. Dual-energy (DE) radiography has been suggested as the most effective method to eliminate bone contrast for better lung tumor visualization. DE radiography also provides a bone image from which benign nodules can be identified by the presence of nodule calcification. The purpose of this study is to evaluate the performance of a film-screen based DE, single exposure technique in lung nodule detection and to improve its performance by both hardware (HD) and software developments (SD) to increase the accuracy of lung cancer diagnosis. Previous implementation of the technique resulted in small residual tissue contrast and incomplete tissue subtraction due to screen selection and x-ray beam hardening, respectively. HD, including uses of a new screen pair (Y 2 O 2 S/CaWO 4 ) and a K-edge filter (europium), were studied to improve residual tissue contrast by increasing the energy separation. Successful SD included a three-dimensional interpolation algorithm and noise suppression methods to achieve complete tissue subtraction and noise reduction, respectively. The results show that the new screen pair performed better than LaOBr/CaWo 4 ; the use of K-edge filter produced more residual tissue contrast than that obtained without it. Even though the dual exposure technique performed better than the single exposure technique in a simulated lung nodule detection study, the difference between the two techniques was statistically insignificant and they both performed better than CCR. Based on these encouraging results, the author concludes that the film-screen based DE, single exposure technique, with the HD and SD holds promise for further clinical study

Characterization by Suppression Subtractive Hybridization of Transcripts That Are Differentially Expressed in Leaves of Anthracnose-Resistant Ramie Cultivar.

Science.gov (United States)

Xuxia, Wang; Jie, Chen; Bo, Wang; Lijun, Liu; Hui, Jiang; Diluo, Tang; Dingxiang, Peng

2012-01-01

For the purpose of screening putative anthracnose resistance-related genes of ramie ( Boehmeria nivea L. Gaud), a cDNA library was constructed by suppression subtractive hybridization using anthracnose-resistant cultivar Huazhu no. 4. The cDNAs from Huazhu no. 4, which were infected with Colletotrichum gloeosporioides , were used as the tester and cDNAs from uninfected Huazhu no. 4 as the driver. Sequencing analysis and homology searching showed that these clones represented 132 single genes, which were assigned to functional categories, including 14 putative cellular functions, according to categories established for Arabidopsis . These 132 genes included 35 disease resistance and stress tolerance-related genes including putative heat-shock protein 90, metallothionein, PR-1.2 protein, catalase gene, WRKY family genes, and proteinase inhibitor-like protein. Partial disease-related genes were further analyzed by reverse transcription PCR and RNA gel blot. These expressed sequence tags are the first anthracnose resistance-related expressed sequence tags reported in ramie.

Utility of noise addition image made by using water phantom and image addition and subtraction software

International Nuclear Information System (INIS)

Watanabe, Ryo; Aoki, Takahiro; Hayano, Mizuho; Ogawa, Masato; Mituzono, Hiroki; Watanabe, Yuka

2010-01-01

In optimizing exposures, it is very important to evaluate the impact of image noise on image quality. To realize this, there is a need to evaluate how much image noise will make the subject disease invisible. But generally it is very difficult to shoot images of different quality in a clinical examination. Thus, a method to create a noise addition image by adding the image noise to raw data has been reported. However, this approach requires a special system, so it is difficult to implement in many facilities. We have invented a method to easily create a noise addition image by using the water phantom and image add-subtract software that accompanies the device. To create a noise addition image, first we made a noise image by subtracting the water phantom with different standard deviation (SD). A noise addition image was then created by adding the noise image to the original image. By using this method, a simulation image with intergraded SD can be created from the original. Moreover, the noise frequency component of the created noise addition image is as same as the real image. Thus, the relationship of image quality to SD in the clinical image can be evaluated. Although this method is an easy method of LDSI creation on image data, a noise addition image can be easily created by using image addition and subtraction software and water phantom, and this can be implemented in many facilities. (author)

Predicting the effect of spectral subtraction on the speech recognition threshold based on the signal-to-noise ratio in the envelope domain

DEFF Research Database (Denmark)

Jørgensen, Søren; Dau, Torsten

2011-01-01

rarely been evaluated perceptually in terms of speech intelligibility. This study analyzed the effects of the spectral subtraction strategy proposed by Berouti at al. [ICASSP 4 (1979), 208-211] on the speech recognition threshold (SRT) obtained with sentences presented in stationary speech-shaped noise....... The SRT was measured in five normal-hearing listeners in six conditions of spectral subtraction. The results showed an increase of the SRT after processing, i.e. a decreased speech intelligibility, in contrast to what is predicted by the Speech Transmission Index (STI). Here, another approach is proposed......, denoted the speech-based envelope power spectrum model (sEPSM) which predicts the intelligibility based on the signal-to-noise ratio in the envelope domain. In contrast to the STI, the sEPSM is sensitive to the increased amount of the noise envelope power as a consequence of the spectral subtraction...

Multi-section CT angiography compared with digital subtraction angiography in diagnosing major arterial hemorrhage in inflammatory pancreatic disease

International Nuclear Information System (INIS)

Hyare, Harpreet; Desigan, Sharmini; Nicholl, Helen; Guiney, Michael J.; Brookes, Jocelyn A.; Lees, William R.

2006-01-01

Purpose: Major arterial hemorrhage is an uncommon but serious complication of pancreatitis with high morbidity and mortality. Digital subtraction angiography (DSA) has long been the gold standard for the detection of a visceral artery pseudoaneurysm or for the site of active bleeding in patients with pancreatitis. Multi-section CT angiography is a minimally invasive technique which can provide high-resolution and high-contrast images of the arterial lumen and wall, with a much lower risk of complication and morbidity compared to DSA. The aim of this study was to determine the accuracy of multi-section CT angiography for the diagnosis of arterial complications of inflammatory pancreatitic disease. Materials and methods: A retrospective analysis of all patients undergoing visceral angiography for major bleeding as a complication of pancreatitis between 1998 and 2004 was performed. Twenty-nine studies in 25 patients (20 males, 5 females) with a mean age of 50.9 years (range 11-67 years) were identified where multi-section CT angiography was performed in the 24 h preceding the digital subtraction angiogram. Results: Digital subtraction angiography detected a pseudoaneurysm or contrast extravasation in 19 studies and no bleeding was demonstrated in 9 studies. CT angiography correctly identified the site and type of bleeding in 18 of the 19 positive studies. CT angiography detected extravasation of contrast in one study that was not demonstrated on digital subtraction angiography. The sensitivity and specificity for multi-section CT angiography for the detection of major arterial bleeding on a background of pancreatitis were 0.947 and 0.900, respectively. Conclusion: Multi-section CT angiography is a sensitive and accurate technique for the detection of major arterial hemorrhage in inflammatory pancreatic disease and should be considered as the first investigation in the management of these patients

Digital video subtraction fluorography (DVSF) in the diagnosis of bronchial abnormality associated with congenital heart diseases

International Nuclear Information System (INIS)

Sano, Tetsuya; Arisawa, Jun; Nakajima, Toru

1990-01-01

To assess bronchial morphology and abnormality, 14 children with congenital heart diseases including 2 postoperative patients (age, 2 m.-4 yr) were studied by digital video subtraction fluorography (DVSF) using digital subtraction and image processing system (Philips, DVI-2). This newly developed technique clearly defined bronchial anatomy in all 14 patients. Bronchial situs could be determined in all 8 patients with complex heart anomalies. Out of 8 patients with respiratory distress in this study, obvious bronchial stenosis or obstruction was found by DVSF in 5 patients. Thus, DVSF image defined anatomies of main and lobar bronchi more clearly than previous noninvasive methods. Moreover, DVSF is noninvasive and easily performed even for small infants and critically ill patients. In conclusion, DVSF may be a useful technique to assess bronchial morphology and abnormality in patients with congenital heart diseases. (author)

Suppression subtractive hybridization as a tool to identify anthocyanin metabolism-related genes in apple skin.

Science.gov (United States)

Ban, Yusuke; Moriguchi, Takaya

2010-01-01

The pigmentation of anthocyanins is one of the important determinants for consumer preference and marketability in horticultural crops such as fruits and flowers. To elucidate the mechanisms underlying the physiological process leading to the pigmentation of anthocyanins, identification of the genes differentially expressed in response to anthocyanin accumulation is a useful strategy. Currently, microarrays have been widely used to isolate differentially expressed genes. However, the use of microarrays is limited by its high cost of special apparatus and materials. Therefore, availability of microarrays is limited and does not come into common use at present. Suppression subtractive hybridization (SSH) is an alternative tool that has been widely used to identify differentially expressed genes due to its easy handling and relatively low cost. This chapter describes the procedures for SSH, including RNA extraction from polysaccharides and polyphenol-rich samples, poly(A)+ RNA purification, evaluation of subtraction efficiency, and differential screening using reverse northern in apple skin.

Two-step digit-set-restricted modified signed-digit addition-subtraction algorithm and its optoelectronic implementation.

Science.gov (United States)

Qian, F; Li, G; Ruan, H; Jing, H; Liu, L

1999-09-10

A novel, to our knowledge, two-step digit-set-restricted modified signed-digit (MSD) addition-subtraction algorithm is proposed. With the introduction of the reference digits, the operand words are mapped into an intermediate carry word with all digits restricted to the set {1, 0} and an intermediate sum word with all digits restricted to the set {0, 1}, which can be summed to form the final result without carry generation. The operation can be performed in parallel by use of binary logic. An optical system that utilizes an electron-trapping device is suggested for accomplishing the required binary logic operations. By programming of the illumination of data arrays, any complex logic operations of multiple variables can be realized without additional temporal latency of the intermediate results. This technique has a high space-bandwidth product and signal-to-noise ratio. The main structure can be stacked to construct a compact optoelectronic MSD adder-subtracter.

201Tl-99mTc subtraction scintigraphy as a preoperative localization procedure for persistent primary and secondary hyperparathyroidism

International Nuclear Information System (INIS)

Geipel, D.; Mischke, W.; Deckart, H.; Weiss, M.L.

1989-01-01

5 patients with a persistent hyperparathyroidism underwent thallium-technetium subtraction scintigraphy prior to reoperation. In all cases the fidings obtained by scintigraphy were confirmed by operation. Based on the preoperative localization of parathyroid adenomas and hyperplastic parathyroid bodies, respectively, their extirpation could be performed in short time. This new nuclear medicine localization procedure for identifying hyperparathyroidism has proved to be useful both in the cervical region and the mediastinum. Thus, as a sensitive method with a non-invasive character this procedure should be applied to reoperations before any other localization method. The indication for performing thallium-technetium subtraction scintigraphy as well as its evaluation have to be carried out in close collaboration between surgeons and nuclear medicine specialists. (author)

Optimizing Energy Consumption in Vehicular Sensor Networks by Clustering Using Fuzzy C-Means and Fuzzy Subtractive Algorithms

Science.gov (United States)

Ebrahimi, A.; Pahlavani, P.; Masoumi, Z.

2017-09-01

Traffic monitoring and managing in urban intelligent transportation systems (ITS) can be carried out based on vehicular sensor networks. In a vehicular sensor network, vehicles equipped with sensors such as GPS, can act as mobile sensors for sensing the urban traffic and sending the reports to a traffic monitoring center (TMC) for traffic estimation. The energy consumption by the sensor nodes is a main problem in the wireless sensor networks (WSNs); moreover, it is the most important feature in designing these networks. Clustering the sensor nodes is considered as an effective solution to reduce the energy consumption of WSNs. Each cluster should have a Cluster Head (CH), and a number of nodes located within its supervision area. The cluster heads are responsible for gathering and aggregating the information of clusters. Then, it transmits the information to the data collection center. Hence, the use of clustering decreases the volume of transmitting information, and, consequently, reduces the energy consumption of network. In this paper, Fuzzy C-Means (FCM) and Fuzzy Subtractive algorithms are employed to cluster sensors and investigate their performance on the energy consumption of sensors. It can be seen that the FCM algorithm and Fuzzy Subtractive have been reduced energy consumption of vehicle sensors up to 90.68% and 92.18%, respectively. Comparing the performance of the algorithms implies the 1.5 percent improvement in Fuzzy Subtractive algorithm in comparison.

The data analysis of the single well injection-withdraw tracer experiment using the MACRO II

International Nuclear Information System (INIS)

Shirakawa, Toshihiko; Kanazawa, Yasuo; Hatanaka, Koichiro

2001-04-01

On understanding the radionuclide transport in natural barrier in radioactive waste isolation research, the macroscopic dispersion in heterogeneous permeability field in the underground rock is regarded as an important process. Therefore, we have conducted lots of tracer experiments by the MACRO II facility with an artificially constructed heterogeneous permeability field. In order to study the scale dependence of dispersion coefficients in case of laboratory experiments, we placed the flow cell horizontally, and conducted injection-withdraw tracer experiment with a single well. We have conducted 15 cases experiments. These cases were prepared by changing a position of single well and the injection-withdraw time. At each position we have conducted 9 cases and 6 cases experiments. In this report, we evaluated the macroscopic dispersion coefficients by the fitting of analytical solution to breakthrough curve measured by the 15 cases pumping tracer experiment. Consequently, we could evaluate the dispersion coefficients for 12 cases of 15 cases. Then, we discussed the relation between a injection-withdraw flow rate and a property of heterogeneous media and dispersion coefficient. The conclusions obtained from the results of the evaluation are summarized as follows, It was found that the macroscopic dispersion coefficients tend to be increased with increase of the average radius of tracer front spread around a single well. We have conducted any experiments with s single well settled at two positions. In case of that there is low permeability around a single well, we found dispersion coefficients are large. In case of that there is high permeability around a single well, we found dispersion coefficients are small. In three cases that we could not evaluate because of incorrect accuracy of fitting, we have found it possible that there is some points that dispersion coefficients were strikingly small in tracer front. (author)

Field trial of a fast single-pass transmit-receive probe during Gentilly II steam generator tube inspection

International Nuclear Information System (INIS)

Obrutsky, L.; Cantin, M.; Renaud, J.; Cecco, V.; Lakhan, R.; Sullivan, S.

2000-01-01

A new generation of transmit-receive single-pass probes, denoted as C6 or X probe, was field tested during the Gentilly II, 2000 steam generator tube inspection. This probe has a performance equivalent to rotating probes and can be used for tubesheet and full-length inspection at an inspection speed equivalent to that of bobbin probes. Existing C3 transmit-receive probes have been demonstrated to be effective in detecting circumferential cracks. The C5 probe can detect both circumferential and axial cracks and volumetric defects but cannot discriminate between them. The C6 probe expands on the capabilities of both probes in a single probe head. It can simultaneously detect and discriminate between circumferential and axial cracks to satisfy different plugging criteria. It has excellent coverage, good defect detectability, and improved sizing and characterization. Probe data is displayed in C-scan format so that the amount of data to be analyzed is similar to rotating probes. The C6 probe will significantly decrease inspection time and the need for re-inspection and tube pulling. This paper describes the advantages of the probe and demonstrates its capabilities employing signals from tube samples with calibration flaws and laboratory induced cracks. It shows the results from the field trial of the probe at Gentilly II and describes the instrumentation, hardware and software used for the inspection. (author)

Field trial of a fast single-pass transmit-receive probe during Gentilly II steam generator tube inspection

International Nuclear Information System (INIS)

Obrutsky, L.; Cantin, M.; Renaud, J.; Cecco, V.; Lakhan, R.; Sullivan, S.

2000-01-01

A new generation of transmit-receive single-pass probes, denoted as C6 or X probe, was field-tested during the Gentilly II, 2000 steam generator tube inspection. This probe has a performance equivalent to rotating probes and can be used for tubesheet and full-length inspection at an inspection speed equivalent to that of bobbin probes. Existing C3 transmit-receive probes have been demonstrated to be effective in detecting circumferential cracks. The C5 probe can detect both circumferential and axial cracks and volumetric defects but cannot discriminate between them. The C6 probe expands on the capabilities of both probes in a single probe head. It can simultaneously detect and discriminate between circumferential and axial cracks to satisfy different plugging criteria. It has excellent coverage, good defect detectability, and improved sizing and characterization. Probe data is displayed in C-scan format so that the amount of data to be analyzed is similar to rotating probes. The C6 probe will significantly decrease inspection time and the need for re-inspection and tube pulling. This paper describes the advantages of the probe and demonstrates its capabilities employing signals from tube samples with calibration flaws and laboratory induced cracks. It shows the results from the field trial of the probe at Gentilly II and describes the instrumentation, hardware and software used for the inspection. (author)

On Semiotics and Jumping Frogs: The Role of Gesture in the Teaching of Subtraction

Science.gov (United States)

Farrugia, Marie Therese

2017-01-01

In this article, I describe a research/teaching experience I undertook with a class of 5-year-old children in Malta. The topic was subtraction on the number line. I interpret the teaching/learning process through a semiotic perspective. In particular, I highlight the role played by the gesture of forming "frog jumps" on the number line.…

Assessment of maximal myocardial perfusion by ECG-triggered digital subtraction angiography

Energy Technology Data Exchange (ETDEWEB)

Pijls, N.H.J.; Uijen, G.J.H.; Werf, T. van der (Katholieke Univ. Nijmegen (Netherlands). Cardiology Dept.)

1991-01-01

Early studies about calculation of coronary blood flow by analysis of contrast agent passage on the coronary arteriogram were reported more than 2 decades ago by Rutishauser et al. and Smith et al. Thereafter is was shown that visualization of contrast passage through the myocardium could be enhanced by ECG-triggered digital subtraction imaging and it was suggested that myocardial flow could be calculated by studying the temporal changes in contrast intensity in a myocardial region of interest (ROI) as a function of time: the time density curve (TDC). (orig./GDG).

Dissociation of Subtraction and Multiplication in the Right Parietal Cortex: Evidence from Intraoperative Cortical Electrostimulation

Science.gov (United States)

Yu, Xiaodan; Chen, Chuansheng; Pu, Song; Wu, Chenxing; Li, Yongnian; Jiang, Tao; Zhou, Xinlin

2011-01-01

Previous research has consistently shown that the left parietal cortex is critical for numerical processing, but the role of the right parietal lobe has been much less clear. This study used the intraoperative cortical electrical stimulation approach to investigate neural dissociation in the right parietal cortex for subtraction and…

Single d(ApG)/cis-diamminedichloroplatinum(II) adduct-induced mutagenesis in Escherichia coli

International Nuclear Information System (INIS)

Burnouf, D.; Fuchs, R.P.P.; Gauthier, C.; Chottard, J.C.

1990-01-01

The mutation spectrum induced by the widely used antitumor drug cis-diamminedichloroplatinum(II) (cis-DDP) showed that cisDDP[d(ApG)] adducts, although they account for only 25% of the lesions formed are ∼5 times more mutagenic than the major GG adduct. The authors report the construction of vectors bearing a single cisDDP[d(ApG)] lesion and their use in mutagenesis experiments in Escherichia coli. The mutagenic processing of the lesion is found to depend strictly on induction of the SOS system of the bacterial host cells. In SOS-induced cells, mutation frequencies of 1-2% were detected. All these mutations are targeted to the 5' base of the adduct. Single A → T transversions are mainly observed (80%), whereas A → G transitions account for 10% of the total mutations. Tandem base-pair substitutions involving the adenine residue and the thymine residue immediately 5' to the adduct occur at a comparable frequency (10%). No selective loss of the strand bearing the platinum adduct was seen, suggesting that, in vivo, cisDDP[d(ApG)] adducts are not blocking lesions. The high mutation specificity of cisDDP-[d(ApG)]-induced mutagenesis is discussed in relation to structural data

Spectral K-edge subtraction imaging of experimental non-radioactive barium uptake in bone.

Science.gov (United States)

Panahifar, Arash; Samadi, Nazanin; Swanston, Treena M; Chapman, L Dean; Cooper, David M L

2016-12-01

To evaluate the feasibility of using non-radioactive barium as a bone tracer for detection with synchrotron spectral K-edge subtraction (SKES) technique. Male rats of 1-month old (i.e., developing skeleton) and 8-month old (i.e., skeletally mature) were orally dosed with low dose of barium chloride (33mg/kg/day Ba 2+ ) for 4weeks. The fore and hind limbs were dissected for imaging in projection and computed tomography modes at 100μm and 52μm pixel sizes. The SKES method utilizes a single bent Laue monochromator to prepare a 550eV energy spectrum to encompass the K-edge of barium (37.441keV), for collecting both 'above' and 'below' the K-edge data sets in a single scan. The SKES has a very good focal size, thus limits the 'crossover' and motion artifacts. In juvenile rats, barium was mostly incorporated in the areas of high bone turnover such as at the growth plate and the trabecular surfaces, but also in the cortical bone as the animals were growing at the time of tracer administration. However, the adults incorporated approximately half the concentration and mainly in the areas where bone remodeling was predominant and occasionally in the periosteal and endosteal layers of the diaphyseal cortical bone. The presented methodology is simple to implement and provides both structural and functional information, after labeling with barium, on bone micro-architecture and thus has great potential for in vivo imaging of pre-clinical animal models of musculoskeletal diseases to better understand their mechanisms and to evaluate the efficacy of pharmaceuticals. Copyright © 2016 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

Single peak parameters technique for simultaneous measurements: Spectrophotometric sequential injection determination of Fe(II) and Fe(III).

Science.gov (United States)

Kozak, J; Paluch, J; Węgrzecka, A; Kozak, M; Wieczorek, M; Kochana, J; Kościelniak, P

2016-02-01

Spectrophotometric sequential injection system (SI) is proposed to automate the method of simultaneous determination of Fe(II) and Fe(III) on the basis of parameters of a single peak. In the developed SI system, sample and mixture of reagents (1,10-phenanthroline and sulfosalicylic acid) are introduced into a vessel, where in an acid environment (pH≅3) appropriate compounds of Fe(II) and Fe(III) with 1,10-phenanthroline and sulfosalicylic acid are formed, respectively. Then, in turn, air, sample, EDTA and sample again, are introduced into a holding coil. After the flow reversal, a segment of air is removed from the system by an additional valve and as EDTA replaces sulfosalicylic acid forming a more stable colorless compound with Fe(III), a complex signal is registered. Measurements are performed at wavelength 530 nm. The absorbance measured at minimum of the negative peak and the area or the absorbance measured at maximum of the signal can be used as measures corresponding to Fe(II) and Fe(III) concentrations, respectively. The time of the peak registration is about 2 min. Two-component calibration has been applied to analysis. Fe(II) and Fe(III) can be determined within the concentration ranges of 0.04-4.00 and 0.1-5.00 mg L(-1), with precision less than 2.8% and 1.7% (RSD), respectively and accuracy better than 7% (RE). The detection limit is 0.04 and 0.09 mg L(-1) for Fe(II) and Fe(III), respectively. The method was applied to analysis of artesian water samples. Copyright © 2015 Elsevier B.V. All rights reserved.

Identification of derlin-1 as a novel growth factor-responsive endothelial antigen by suppression subtractive hybridization

International Nuclear Information System (INIS)

Ran Yuliang; Jiang Yangfu; Zhong Xing; Zhou Zhuan; Liu Haiyan; Hu Hai; Lou Jinning; Yang Zhihua

2006-01-01

Endothelial cells play an important regulatory role in embryonic development, reproductive functions, tumor growth and progression. In the present study, the suppression subtractive hybridization (SSH) method was employed to identify differentially expressed genes between non-stimulated endothelial cells and activated endothelial cells. Following mRNA isolation of non-stimulated and hepatocellular carcinoma homogenate-stimulated cells, cDNAs of both populations were prepared and subtracted by suppressive PCR. Sequencing of the enriched cDNAs identified a couple of genes differentially expressed, including derlin-1. Derlin-1 was significantly up-regulated by tumor homogenates, VEGF, and endothelial growth supplements in a dose-dependent manner. Knock-down of derlin-1 triggered endothelial cell apoptosis, inhibited endothelial cell proliferation, and blocked the formation of a network of tubular-like structures. Our data reveal that derlin-1 is a novel growth factor-responsive endothelial antigen that promotes endothelial cell survival and growth

Optical image encryption based on real-valued coding and subtracting with the help of QR code

Science.gov (United States)

Deng, Xiaopeng

2015-08-01

A novel optical image encryption based on real-valued coding and subtracting is proposed with the help of quick response (QR) code. In the encryption process, the original image to be encoded is firstly transformed into the corresponding QR code, and then the corresponding QR code is encoded into two phase-only masks (POMs) by using basic vector operations. Finally, the absolute values of the real or imaginary parts of the two POMs are chosen as the ciphertexts. In decryption process, the QR code can be approximately restored by recording the intensity of the subtraction between the ciphertexts, and hence the original image can be retrieved without any quality loss by scanning the restored QR code with a smartphone. Simulation results and actual smartphone collected results show that the method is feasible and has strong tolerance to noise, phase difference and ratio between intensities of the two decryption light beams.

Use of the digital subtraction angiography in the study of aortic dissecting aneurisms

Energy Technology Data Exchange (ETDEWEB)

Orlacchio, A; Fanucci, E; Pocek, M; Cirillo, F

1984-01-01

Authors on the basis of their data discuss the opportunity affered by the digital subtraction angiography (DSA) in the study of the aorta dissecting aneurisms. DSA as a consequence of the image formation and processing techniques allows the optimization of information concerning the reflux kinetics in the true and false lumen and offers a vascular mapping of the body district under study which is enough indicative to the subsequent therapy.

Phantom evaluation of simultaneous thallium-201/technetium-99m acquisition in single-photon emission tomography

International Nuclear Information System (INIS)

Cao Zongjian; Chen, C.C.; Maunoury, C.; Holder, L.E.; Abraham, T.C.; Tehan, A.

1996-01-01

This study investigated downscatter effects in cardiac single-photon emission tomographic studies with simultaneous thallium-201/technetium-99m acquisition, and evaluated a previously proposed subtraction technique for downscatter compensation. Ten studies were carried out with different defect sizes and locations and varying activity distributions using four energy windows: 70±10% keV, 140±10% keV, 100±10% KeV, and 103±16% keV. The subtraction technique used the 100- or 103-keV data to remove scattered 99m Tc counts from the 70-keV data. The size and contrast of infarcts in the dual-isotope 70-keV image were artificially decreased compared to those in the 140-keV image, caused by scattered 99m Tc counts that were comparable to the primary 201 Tl counts in the 70-keV window. The subtraction technique produced larger defects and more heterogeneous activity in the myocardial wall in dual-isotope 70-keV images compared to the corresponding 201 Tl-only images. These artifacts were caused by the markedly different spatial distributions of scattered 99m Tc counts in the 100-keV (or 103-keV) window as compared with the 70-keV window. It is concluded that scattered 99m Tc photons may cause overestimation of ischemia and myocardial viability in simultaneous dual-isotope patient studies. The proposed subtraction technique was inaccurate and produced image artifacts. Adequate downscatter compensation methods must be developed before applying simultaneous 201 Tl/ 99m Tc acquisition in clinical practice. (orig.). With 6 figs., 3 tabs

Detection of broad ultraviolet Fe II lines in the spectrum of NGC 1068

International Nuclear Information System (INIS)

Snijders, M.A.J.; Netzer, Hagai; Boksenberg, A.

1986-01-01

Ultraviolet observations of the nucleus of NGC 1068, obtained by the IUE over a period of 5 yr, are combined to give a high signal-to-noise spectrum of this source. The ultraviolet stellar continuum, obtained by comparison with ground-based data, is subtracted to show the nuclear non-stellar component. The resulting spectrum shows clearly the presence of strong broad FeII emission bands similar to those observed in many broad-line objects. Broad profiles are also seen in other strong emission lines. These observations confirm the recent discovery of an optical Seyfert type 1 spectrum in NGC 1068. (author)

Analysis of Radiation Effects in Digital Subtraction Angiography of Intracranial Artery Stenosis.

Science.gov (United States)

Guo, Chaoqun; Shi, Xiaolei; Ding, Xianhui; Zhou, Zhiming

2018-04-21

Intracranial artery stenosis (IAS) is the most common cause for acute cerebral accidents. Digital subtraction angiography (DSA) is the gold standard to detect IAS and usually brings excess radiation exposure to examinees and examiners. The artery pathology might influence the interventional procedure, causing prolonged radiation effects. However, no studies on the association between IAS pathology and operational parameters are available. A retrospective analysis was conducted on 93 patients with first-ever stroke/transient ischemic attack, who received DSA examination within 3 months from onset in this single center. Comparison of baseline characteristics was determined by 2-tailed Student's t-test or the chi-square test between subjects with and without IAS. A binary logistic regression analysis was performed to determine the association between IAS pathology and the items with a P value 42 with IAS and 51 without IAS) in this study. The 2 groups shared no significance of the baseline characteristics (P > 0.05). We found a significantly higher total time, higher kerma area product, greater total dose, and greater DSA dose in the IAS group than in those without IAS (P IAS pathology (P 0.05). IAS pathology would indicate a prolonged total time of DSA procedure in clinical practice. However, the radiation effects would not change with pathologic changes. Copyright © 2018 Elsevier Inc. All rights reserved.

Synthesis, characterization and single crystal x-ray analysis of a complex of iron(II) bis(2,4-dimethylphenyl)dithiophosphate with 4-ethylpyridine

Energy Technology Data Exchange (ETDEWEB)

Kumar, Sandeep; Andotra, Savit; Kaur, Mandeep [University of Jammu, Department of Chemistry (India); Gupta, Vivek K.; Kant, Rajni [Department of Physics and Electronics, University of Jammu, X-ray Crystallographic Laboratory (India); Pandey, Sushil K., E-mail: kpsushil@rediffmail.com [University of Jammu, Department of Chemistry (India)

2016-09-15

Complex of iron(II) bis(2,4-dimethylphenyl)dithiophosphate with 4-ethylpyridine [((2,4- (CH{sub 3}){sub 2}C{sub 6}H{sub 3}O)2PS2)2Fe(NC{sub 5}H{sub 4}(C{sub 2}H{sub 5})-4){sub 2}] is synthesized and characterized by elemental analysis, magnetic moment, IR spectroscopy and single crystal X-ray analysis. Complex crystallizes in the monoclinic sp. gr. P2{sub 1}/n, Z = 2. Crystal structure consists of mononuclear units with Fe(II) ion chelated by four S atoms of the two diphenyldithiophosphate ligands in bidentate manner. N atoms from two 4-ethylpyridine ligands are axially coordinated to the Fe(II) atom leading to an octahedral geometry.

Clinical evaluation of bone-subtraction CT angiography (BSCTA) in head and neck imaging

International Nuclear Information System (INIS)

Lell, M.; Anders, K.; Bautz, W.; Klotz, E.; Ditt, H.; Tomandl, B.F.

2006-01-01

Fifty-one patients were examined with bone subtraction CT angiography (BSCTA). Data were acquired on 4-and 64-slice spiral CT systems. The post-processing method is based on fully automatic registration of non-enhanced and contrast-enhanced CT data and subsequent selective bone removal. Vascular structures and brain tissue are retained with the original CTA noise level. Image quality and delineation of the pathologic process were assessed and artifacts introduced by the bone removal process recorded. The bone subtraction algorithm worked successfully in all examinations. The processing time was 6 min on average. Image quality was rated excellent in 20 (39%), good in 26 (51%) and acceptable in 5 (10%) patients. Ophthalmic arteries were visible in 12 (24%) patients bilaterally, in 13 (25%) patients unilaterally and in 26 (51%) patients at least at the origin. BSCTA improved visualization of the infraclinoid ICA and the vertebral arteries. The depiction of stenosis of the extracranial ICA and supraclinoid aneurysms was not significantly improved. In patients with suspicion of sinus thrombosis, BSCTA and conventional CTA yielded similar results. To conclude, BSCTA improves the visualization of vessels with close contact to bone and can improve the diagnostic accuracy and therapy planning of infraclinoid aneurysms. (orig.)

Influence of the large-small split effect on strategy choice in complex subtraction.

Science.gov (United States)

Xiang, Yan Hui; Wu, Hao; Shang, Rui Hong; Chao, Xiaomei; Ren, Ting Ting; Zheng, Li Ling; Mo, Lei

2018-04-01

Two main theories have been used to explain the arithmetic split effect: decision-making process theory and strategy choice theory. Using the inequality paradigm, previous studies have confirmed that individuals tend to adopt a plausibility-checking strategy and a whole-calculation strategy to solve large and small split problems in complex addition arithmetic, respectively. This supports strategy choice theory, but it is unknown whether this theory also explains performance in solving different split problems in complex subtraction arithmetic. This study used small, intermediate and large split sizes, with each split condition being further divided into problems requiring and not requiring borrowing. The reaction times (RTs) for large and intermediate splits were significantly shorter than those for small splits, while accuracy was significantly higher for large and middle splits than for small splits, reflecting no speed-accuracy trade-off. Further, RTs and accuracy differed significantly between the borrow and no-borrow conditions only for small splits. This study indicates that strategy choice theory is suitable to explain the split effect in complex subtraction arithmetic. That is, individuals tend to choose the plausibility-checking strategy or the whole-calculation strategy according to the split size. © 2016 International Union of Psychological Science.

Magneto-structural correlations in a family of Fe(II)Re(IV)(CN)2 single-chain magnets: density functional theory and ab initio calculations.

Science.gov (United States)

Zhang, Yi-Quan; Luo, Cheng-Lin; Wu, Xin-Bao; Wang, Bing-Wu; Gao, Song

2014-04-07

Until now, the expressions of the anisotropic energy barriers Δξ and ΔA, using the uniaxial magnetic anisotropy D, the intrachain coupling strength J, and the high-spin ground state S for single-chain magnets (SCMs) in the intermediate region between the Ising and the Heisenberg limits, were unknown. To explore this relationship, we used density functional theory and ab initio methods to obtain expressions of Δξ and ΔA in terms of D, J, and S of six R4Fe(II)-Re(IV)Cl4(CN)2 (R = diethylformamide (1), dibutylformamide (2), dimethylformamide (3), dimethylbutyramide (4), dimethylpropionamide (5), and diethylacetamide (6)) SCMs in the intermediate region. The ΔA value for compounds 1-3 was very similar to the magnetic anisotropic energy of a single Fe(II), while the value of Δξ was predicted using the exchange interaction of Fe(II) with the neighboring Re(IV), which could be expressed as 2JSReSFe. Similar to compounds 1-3, the anisotropy energy barrier ΔA of compounds 4 and 5 was also equal to (Di - Ei)SFe(2), but the correlation energy Δξ was closely equal to 2JSReSFe(cos 98.4 - cos 180) due to the reversal of the spins on the opposite Fe(II). For compound 6, one unit cell of Re(IV)Fe(II) was regarded as a domain wall since it had two different Re(IV)-Fe(II) couplings. Thus, the Δξ of compound 6 was expressed as 4J″SRe1Fe1SRe2Fe2, where J″ was the coupling constant of the neighboring unit cells of Re1Fe1 and Re2Fe2, and ΔA was equal to the anisotropic energy barrier of one domain wall given by DRe1Fe1(S(2)Re1Fe1 - 1/4).

Subtractive Inhibition Assay for the Detection of E. coli O157:H7 Using Surface Plasmon Resonance

Directory of Open Access Journals (Sweden)

Chengyan Si

2011-03-01

Full Text Available A surface plasmon resonance (SPR immunosensor was developed for the detection of E. coli O157:H7 by means of a new subtractive inhibition assay. In the subtractive inhibition assay, E. coli O157:H7 cells and goat polyclonal antibodies for E. coli O157:H7 were incubated for a short of time, and then the E. coli O157:H7 cells which bound antibodies were removed by a stepwise centrifugation process. The remaining free unbound antibodies were detected through interaction with rabbit anti-goat IgG polyclonal antibodies immobilized on the sensor chip using a BIAcore 3000 biosensor. The results showed that the signal was inversely correlated with the concentration of E. coli O157:H7 cells in a range from 3.0 × 104 to 3.0 × 108 cfu/mL with a detection limit of 3.0 × 104 cfu/mL. Compared with direct SPR by immobilizing antibodies on the chip surface to capture the bacterial cells and ELISA for E. coli O157:H7 (detection limit: both 3.0 × 105 cfu/mL in this paper, the detection limit of subtractive inhibition assay method was reduced by one order of magnitude. The method simplifies bacterial cell detection to protein-protein interaction, which has the potential for providing a practical alternative for the monitoring of E. coli O157:H7 and other pathogens.

OPTIMIZING ENERGY CONSUMPTION IN VEHICULAR SENSOR NETWORKS BY CLUSTERING USING FUZZY C-MEANS AND FUZZY SUBTRACTIVE ALGORITHMS

Directory of Open Access Journals (Sweden)

A. Ebrahimi

2017-09-01

Full Text Available Traffic monitoring and managing in urban intelligent transportation systems (ITS can be carried out based on vehicular sensor networks. In a vehicular sensor network, vehicles equipped with sensors such as GPS, can act as mobile sensors for sensing the urban traffic and sending the reports to a traffic monitoring center (TMC for traffic estimation. The energy consumption by the sensor nodes is a main problem in the wireless sensor networks (WSNs; moreover, it is the most important feature in designing these networks. Clustering the sensor nodes is considered as an effective solution to reduce the energy consumption of WSNs. Each cluster should have a Cluster Head (CH, and a number of nodes located within its supervision area. The cluster heads are responsible for gathering and aggregating the information of clusters. Then, it transmits the information to the data collection center. Hence, the use of clustering decreases the volume of transmitting information, and, consequently, reduces the energy consumption of network. In this paper, Fuzzy C-Means (FCM and Fuzzy Subtractive algorithms are employed to cluster sensors and investigate their performance on the energy consumption of sensors. It can be seen that the FCM algorithm and Fuzzy Subtractive have been reduced energy consumption of vehicle sensors up to 90.68% and 92.18%, respectively. Comparing the performance of the algorithms implies the 1.5 percent improvement in Fuzzy Subtractive algorithm in comparison.

Density of vibrational States of the light-harvesting complex II of green plants studied by inelastic neutron scattering

CERN Document Server

Pieper, J K; Renger, G; Lechner, R E

2004-01-01

Results of inelastic neutron scattering (INS) experiments are reported for the solubilized trimeric light-harvesting complex of photosystem II (LHC II) in the temperature range from 5 to 100 K. Two incident neutron wavelengths of 2.0 ( similar to 20 meV) and 5.1 A ( similar to 3.2 meV) corresponding to elastic energy resolutions of DeltaE = 0.920 meV and DeltaE = 0.093 meV, respectively, are employed to study INS spectra of LHC II for both neutron energy loss and gain. Solubilized LHC II and D//2O-containing buffer solution are investigated separately in order to properly subtract the contribution of the solvent. The inelastic part of the scattering function S(Q, omega) derived for the LHC II protein resembles the well-known "Boson-peak" and is characterized by a maximum at about 2.5 meV and a strongly asymmetric line shape with a slight tailing toward higher energy transfers. Analysis of the momentum transfer dependence of S(Q, omega) reveals that both the elastic and inelastic contributions to S(Q, omega) e...

Single top quark t W + X production at the LHC a closer look

CERN Document Server

Belyaev, A.

2001-01-01

We have reexamined the tW+X single top-quark production process which is important at the LHC contrary to the Tevatron. The special attention was paid to the treatment of the 2->2[Wt] process and the part of it's next-to-leading correction: 2->3[Wtb] process. We show that 2->3[Wtb] process has to be correctly taken into account with a proper subtraction of the top pair contribution and that it has qualitatively different kinematical distributions from the 2->2[Wt] process. We present the total cross section of the tW+X production to be about 62 pb at QCD scale be taken as a top quark mass, suggest the method of combining Wt and Wtb processes with gauge invariant subtraction of the tt-bar part which allows to reproduce correct kinematical properties and perform a proper event simulation of the tW+X process in the whole kinematical region.

A subtraction scheme for computing QCD jet cross sections at NNLO: regularization of doubly-real emissions

International Nuclear Information System (INIS)

Somogyi, Gabor; Trocsanyi, Zoltan; Del Duca, Vittorio

2007-01-01

We present a generalization of the dipole subtraction scheme for computing jet cross sections in electron-positron annihilation at next-to-next-to-leading order accuracy in perturbative QCD. In this first part we deal with the regularization of the doubly-real contribution to the NNLO correction

A subtraction scheme for computing QCD jet cross sections at NNLO: regularization of doubly-real emissions

Energy Technology Data Exchange (ETDEWEB)

Somogyi, Gabor [University of Debrecen and Institute of Nuclear Research of the Hungarian Academy of Sciences, H-4001 Debrecen, PO Box 51 (Hungary); Trocsanyi, Zoltan [University of Debrecen and Institute of Nuclear Research of the Hungarian Academy of Sciences, H-4001 Debrecen, PO Box 51 (Hungary); Del Duca, Vittorio [Istituto Nazionale di Fisica Nucleare, Sez. di Torino, via P. Giuria, 1 - 10125 Turin (Italy)

2007-01-15

We present a generalization of the dipole subtraction scheme for computing jet cross sections in electron-positron annihilation at next-to-next-to-leading order accuracy in perturbative QCD. In this first part we deal with the regularization of the doubly-real contribution to the NNLO correction.

A subtraction scheme for computing QCD jet cross sections at NNLO: regularization of real-virtual emission

Energy Technology Data Exchange (ETDEWEB)

Somogyi, Gabor; Trocsanyi, Zoltan [University of Debrecen and Institute of Nuclear Research of the Hungarian Academy of Sciences, H-4001 Debrecen, PO Box 51 (Hungary)

2007-01-15

We present a generalization of the dipole subtraction scheme for computing jet cross sections in electron-positron annihilation at next-to-next-to-leading order accuracy in perturbative QCD. In this second part we deal with the regularization of the real-virtual contribution to the NNLO correction.

Postoperative three-dimensional CT angiography after cerebral aneurysm clipping with titanium clips: detection with single detector CT. Comparison with intra-arterial digital subtraction angiography

International Nuclear Information System (INIS)

Sakuma, I.; Tomura, N.; Kinouchi, H.; Takahashi, S.; Otani, T.; Watarai, J.; Mizoi, K.

2006-01-01

AIM: To assess the significance of three-dimensional computed tomography angiography (3D-CTA) in detecting remnant necks after cerebral aneurysm clipping. MATERIALS AND METHODS: A total of 59 patients (77 aneurysms) underwent surgery using titanium clips. Two blinded observers independently evaluated the presence of neck remnants on shaded-surface display (SSD) imaging, volume rendered (VR) imaging, and intra-arterial digital subtraction angiography (IADSA). RESULTS: Mean sensitivity and specificity for detecting neck remnants were 50.0 and 74.2% for SSD imaging, 61.5 and 82.8% for VR imaging, and 92.3 and 92.2% for IADSA, respectively. Receiver operating characteristic (ROC) analysis revealed excellent diagnostic performance for IADSA [mean area under ROC curve (Az)=0.97], and good diagnostic performance for 3D-CTA (Az=0.70 and 0.76 for SSD and VR, respectively). Specificity of VR was better than that SSD (p=0.082), however, there was no significant difference between them. CONCLUSION: Use of 3D-CTA techniques can facilitate postoperative evaluation

Electrochemical characterization of mixed self-assembled films of water-soluble single-walled carbon nanotube-poly(m-aminobenzene sulfonic acid) and Iron(II) tetrasulfophthalocyanine

CSIR Research Space (South Africa)

Agboola, BO

2010-09-01

Full Text Available The redox activities of water-soluble iron(II) tetrasulfophthalocyanine (FeTSPc) and single-walled carbon nanotube-poly(m-aminobenzene sulfonic acid) (SWCNT-PABS) adsorbed on a gold surface precoated with a self-assembled monolayer (SAM) of 2...

An Application of Fuzzy Inference System by Clustering Subtractive Fuzzy Method for Estimating of Product Requirement

Directory of Open Access Journals (Sweden)

Fajar Ibnu Tufeil

2009-06-01

Full Text Available Model fuzzy memiliki kemampuan untuk menjelaskan secara linguistik suatu sistem yang terlalu kompleks. Aturan-aturan dalam model fuzzy pada umumnya dibangun berdasarkan keahlian manusia dan pengetahuan heuristik dari sistem yang dimodelkan. Teknik ini selanjutnya dikembangkan menjadi teknik yang dapat mengidentifikasi aturan-aturan dari suatu basis data yang telah dikelompokkan berdasarkan persamaan strukturnya. Dalam hal ini metode pengelompokan fuzzy berfungsi untuk mencari kelompok-kelompok data. Informasi yang dihasilkan dari metode pengelompokan ini, yaitu informasi tentang pusat kelompok, digunakan untuk membentuk aturan-aturan dalam sistem penalaran fuzzy. Dalam skripsi ini dibahas mengenai penerapan fuzzy infereance system dengan metode pengelompokan fuzzy subtractive clustering, yaitu untuk membentuk sistem penalaran fuzzy dengan menggunakan model fuzzy Takagi-Sugeno orde satu. Selanjutnya, metode pengelompokan fuzzy subtractive clustering diterapkan dalam memodelkan masalah dibidang pemasaran, yaitu untuk memprediksi permintaan pasar terhadap suatu produk susu. Aplikasi ini dibangun menggunakan Borland Delphi 6.0. Dari hasil pengujian diperoleh tingkat error prediksi terkecil yaitu dengan Error Average 0.08%.

Displacement-enhanced entanglement distillation of single-mode-squeezed entangled states

DEFF Research Database (Denmark)

Tipsmark, Anders; Neergaard-Nielsen, Jonas Schou; Andersen, Ulrik Lund

2013-01-01

It has been shown that entanglement distillation of Gaussian entangled states by means of local photon subtraction can be improved by local Gaussian transformations. Here we show that a similar effect can be expected for the distillation of an asymmetric Gaussian entangled state that is produced...... by a single squeezed beam. We show that for low initial entanglement, our largely simplified protocol generates more entanglement than previous proposed protocols. Furthermore, we show that the distillation scheme also works efficiently on decohered entangled states as well as with a practical photon...

Accuracy and precision of polyurethane dental arch models fabricated using a three-dimensional subtractive rapid prototyping method with an intraoral scanning technique.

Science.gov (United States)

Kim, Jae-Hong; Kim, Ki-Baek; Kim, Woong-Chul; Kim, Ji-Hwan; Kim, Hae-Young

2014-03-01

This study aimed to evaluate the accuracy and precision of polyurethane (PUT) dental arch models fabricated using a three-dimensional (3D) subtractive rapid prototyping (RP) method with an intraoral scanning technique by comparing linear measurements obtained from PUT models and conventional plaster models. Ten plaster models were duplicated using a selected standard master model and conventional impression, and 10 PUT models were duplicated using the 3D subtractive RP technique with an oral scanner. Six linear measurements were evaluated in terms of x, y, and z-axes using a non-contact white light scanner. Accuracy was assessed using mean differences between two measurements, and precision was examined using four quantitative methods and the Bland-Altman graphical method. Repeatability was evaluated in terms of intra-examiner variability, and reproducibility was assessed in terms of inter-examiner and inter-method variability. The mean difference between plaster models and PUT models ranged from 0.07 mm to 0.33 mm. Relative measurement errors ranged from 2.2% to 7.6% and intraclass correlation coefficients ranged from 0.93 to 0.96, when comparing plaster models and PUT models. The Bland-Altman plot showed good agreement. The accuracy and precision of PUT dental models for evaluating the performance of oral scanner and subtractive RP technology was acceptable. Because of the recent improvements in block material and computerized numeric control milling machines, the subtractive RP method may be a good choice for dental arch models.

Einstein-Podolsky-Rosen paradox in single pairs of images.

Science.gov (United States)

Lantz, Eric; Denis, Séverine; Moreau, Paul-Antoine; Devaux, Fabrice

2015-10-05

Spatially entangled twin photons provide a test of the Einstein-Podolsky-Rosen (EPR) paradox in its original form of position (image plane) versus impulsion (Fourier plane). We show that recording a single pair of images in each plane is sufficient to safely demonstrate an EPR paradox. On each pair of images, we have retrieved the fluctuations by subtracting the fitted deterministic intensity shape and then have obtained an intercorrelation peak with a sufficient signal to noise ratio to safely distinguish this peak from random fluctuations. A 95% confidence interval has been determined, confirming a high degree of paradox whatever the considered single pairs. Last, we have verified that the value of the variance of the difference between twin images is always below the quantum (poissonian) limit, in order to ensure the particle character of the demonstration. Our demonstration shows that a single image pattern can reveal the quantum and non-local behavior of light.

Does one see gluon condensation after subtraction of mean field perturbation theory from Monte Carlo data

International Nuclear Information System (INIS)

Schlichting, H.

1985-01-01

We do a linearised mean field calculation in axial gauge for the four dimensional mixed fundamental adjoint SU(2) lattice gauge theory and extract the gluon condensate parameter from the expectation values of the plaquette and the action by subtracting mean field perturbation theory from Monte Carlo data. (orig.)

Single-molecule fluorescence polarization study of conformational change in archaeal group II chaperonin.

Directory of Open Access Journals (Sweden)

Ryo Iizuka

Full Text Available Group II chaperonins found in archaea and in eukaryotic cytosol mediate protein folding without a GroES-like cofactor. The function of the cofactor is substituted by the helical protrusion at the tip of the apical domain, which forms a built-in lid on the central cavity. Although many studies on the change in lid conformation coupled to the binding and hydrolysis of nucleotides have been conducted, the molecular mechanism of lid closure remains poorly understood. Here, we performed a single-molecule polarization modulation to probe the rotation of the helical protrusion of a chaperonin from a hyperthermophilic archaeum, Thermococcus sp. strain KS-1. We detected approximately 35° rotation of the helical protrusion immediately after photorelease of ATP. The result suggests that the conformational change from the open lid to the closed lid state is responsible for the approximately 35° rotation of the helical protrusion.

Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets

International Nuclear Information System (INIS)

Sousa, Josane F; Espreafico, Enilza M

2008-01-01

Melanoma progression occurs through three major stages: radial growth phase (RGP), confined to the epidermis; vertical growth phase (VGP), when the tumor has invaded into the dermis; and metastasis. In this work, we used suppression subtractive hybridization (SSH) to investigate the molecular signature of melanoma progression, by comparing a group of metastatic cell lines with an RGP-like cell line showing characteristics of early neoplastic lesions including expression of the metastasis suppressor KISS1, lack of αvβ3-integrin and low levels of RHOC. Two subtracted cDNA collections were obtained, one (RGP library) by subtracting the RGP cell line (WM1552C) cDNA from a cDNA pool from four metastatic cell lines (WM9, WM852, 1205Lu and WM1617), and the other (Met library) by the reverse subtraction. Clones were sequenced and annotated, and expression validation was done by Northern blot and RT-PCR. Gene Ontology annotation and searches in large-scale melanoma expression studies were done for the genes identified. We identified 367 clones from the RGP library and 386 from the Met library, of which 351 and 368, respectively, match human mRNA sequences, representing 288 and 217 annotated genes. We confirmed the differential expression of all genes selected for validation. In the Met library, we found an enrichment of genes in the growth factors/receptor, adhesion and motility categories whereas in the RGP library, enriched categories were nucleotide biosynthesis, DNA packing/repair, and macromolecular/vesicular trafficking. Interestingly, 19% of the genes from the RGP library map to chromosome 1 against 4% of the ones from Met library. This study identifies two populations of genes differentially expressed between melanoma cell lines from two tumor stages and suggests that these sets of genes represent profiles of less aggressive versus metastatic melanomas. A search for expression profiles of melanoma in available expression study databases allowed us to point to a

Specific heat and magnetization of a ZrB12 single crystal: characterization of a type II/1 superconductor

OpenAIRE

Wang, Yuxing; Lortz, Rolf; Paderno, Yuriy; Filippov, Vladimir; Abe, Satoko; Tutsch, Ulrich; Junod, Alain

2005-01-01

We measured the specific heat, the magnetization, and the magnetoresistance of a single crystal of ZrB12, which is superconducting below Tc ~ 6 K. The specific heat in zero field shows a BCS-type superconducting transition. The normal- to superconducting-state transition changes from first order (with a latent heat) to second order (without latent heat) with increasing magnetic field, indicating that the pure compound is a low-kappa, type-II/1 superconductor in the classification of Auer and ...

Synthesis and Crystal Structures of Luminescent Mononuclear Ni(ii and Cd(ii Complexes with 1,10-phenanthroline

Directory of Open Access Journals (Sweden)

Ecaterina Tocana

2017-12-01

Full Text Available New supramolecular systems of Ni(II and Cd(II with 1,10-phenanthroline constructed by non-covalent interactions have been synthesized and characterized by single-crystal X-ray diffractometry. The smaller nickel(II ion forms a cis complex with outer-sphere perchlorates, while the cadmium(II ion forms a trans complex involving inner-sphere perchlorates. Both compoundsrevealintraligand-basedluminescentproperties.

Heritage Language Learners in Mixed Spanish Classes: Subtractive Practices and Perceptions of High School Spanish Teachers

Science.gov (United States)

Randolph, Linwood J., Jr.

2017-01-01

This qualitative study investigated the language ideologies and instructional practices of an entire Spanish language faculty at a high school in a new gateway state for immigration. The study examined additive and subtractive practices of teachers as they strived to teach Spanish to heritage language learners (HLLs) enrolled in mixed…

Mental Subtraction in High- and Lower Skilled Arithmetic Problem Solvers: Verbal Report versus Operand-Recognition Paradigms

Science.gov (United States)

Thevenot, Catherine; Castel, Caroline; Fanget, Muriel; Fayol, Michel

2010-01-01

The authors used the operand-recognition paradigm (C. Thevenot, M. Fanget, & M. Fayol, 2007) in order to study the strategies used by adults to solve subtraction problems. This paradigm capitalizes on the fact that algorithmic procedures degrade the memory traces of the operands. Therefore, greater difficulty in recognizing them is expected…

320-Multidetector row whole-head dynamic subtracted CT angiography and whole-brain CT perfusion before and after carotid artery stenting: Technical note

International Nuclear Information System (INIS)

San Millan Ruiz, Diego; Murphy, Kieran; Gailloud, Philippe

2010-01-01

Introduction: Multidetector CT (MDCT) is increasingly used for the investigation of neurovascular disorders, but restricted z-axis coverage (3.2 cm for 64-MDCT) currently limits perfusion to a small portion of the brain close to the circle of Willis, and precludes dynamic angiographic appreciation of the entire brain circulation. We illustrate the clinical potential of recently developed 320-MDCT extending the z-axis coverage to 16 cm in a patient with symptomatic carotid artery stenosis. Methods: In a 74-year-old patient presenting with critical symptomatic stenosis of the left CCA, pre- and post-carotid artery stenting whole-head subtracted dynamic MDCT angiography and perfusion were obtained in addition to CT angiography of the supra-aortic trunks. Both whole-head subtracted MDCT angiography and perfusion demonstrated delayed left ICA circulation, which normalized after carotid stenting. Discussion: 320-MDCT offers unprecedented z-axis coverage allowing for whole-brain perfusion and subtracted dynamic angiography of the entire intracranial circulation. These innovations can consolidate the role of MDCT as a first intention imaging technique for cerebrovascular disorders, in particular for the acute management of stroke.

The spectrum of singly ionized yttrium, Y II

International Nuclear Information System (INIS)

Nilsson, A.E.; Johansson, S.; Kurucz, R.L.

1991-01-01

Hollow-cathode spectra of yttrium have been registered in the wavelength region 1000-48800 A. Resonant charge transfer reactions in the light source favour the excitation of Y II, where 174 new levels have been established by means of 1284 newly classified lines. Altogether we report 1521 lines between 235 levels in Y II. The ground complex (4d+5s) 2 is now completely known and a number of Rydberg series have been extended. The new levels belong to the 4dnl (nl=7s, 8s, 9s, 6p, 7p, 4d, 5d, 6d, 7d, 8d, 4f, 5f, 6f, 7f, 5g) and 5snl (nl=7s, 8s, 6p, 6d, 4f, 5f) configurations. Eigenvector compositions, based on paramagnetic calculations including configuration interaction, are given for all levels. The ionization limit has been determined to 98590 ± 5 cm -1 . (orig.)

Method and apparatus for performing digital intravenous subtraction angiography

International Nuclear Information System (INIS)

Stein, J.A.

1986-01-01

This invention relates to digital intravenous subtraction angiography (DISA), and more particularly concerns novel apparatus and techniques for providing high resolution angiograms with equipment that coacts with existing standard medical X-ray equipment. A typical medical X-ray generator provides low mA, continuous X-ray exposures illuminating a standard image intensifier producing an image scanned by a conventional television camera to produce a video signal. An analog-to-digital converter digitizes the signal, and adding means adds the digital frame signals together in real time to provide an intermediate digital signal representing the addition of 5 to 20 frames. Digital storage means store the intermediate image signals. Preferably there are two system memories with means for summing a subsequent intermediate image in the second memory while a previously-formed intermediate image is being transferred to disk storage

Timelike single-logarithm-resummed splitting functions

Energy Technology Data Exchange (ETDEWEB)

Albino, S.; Bolzoni, P.; Kniehl, B.A. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Kotikov, A.V. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Joint Inst. of Nuclear Research, Moscow (Russian Federation). Bogoliubov Lab. of Theoretical Physics

2011-08-15

We calculate the single logarithmic contributions to the quark singlet and gluon matrix of timelike splitting functions at all orders in the modified minimal-subtraction (MS) scheme. We fix two of the degrees of freedom of this matrix from the analogous results in the massive-gluon regularization scheme by using the relation between that scheme and the MS scheme. We determine this scheme transformation from the double logarithmic contributions to the timelike splitting functions and the coefficient functions of inclusive particle production in e{sup +}e{sup -} annihilation now available in both schemes. The remaining two degrees of freedom are fixed by reasonable physical assumptions. The results agree with the fixed-order results at next-to-next-to-leading order in the literature. (orig.)

How to build institutionalization on students: a pilot experiment on a didactical design of addition and subtraction involving negative integers

Science.gov (United States)

Fuadiah, N. F.; Suryadi, D.; Turmudi

2018-05-01

This study focuses on the design of a didactical situation in addition and subtraction involving negative integers at the pilot experiment phase. As we know, negative numbers become an obstacle for students in solving problems related to them. This study aims to create a didactical design that can assist students in understanding the addition and subtraction. Another expected result in this way is that students are introduced to the characteristics of addition and subtraction of integers. The design was implemented on 32 seventh grade students in one of the classes in a junior secondary school as the pilot experiment. Learning activities were observed thoroughly including the students’ responses that emerged during the learning activities. The written documentation of the students was also used to support the analysis in the learning activities. The results of the analysis showed that this method could help the students perform a large number of integer operations that could not be done with a number line. The teacher’s support as a didactical potential contract was still needed to encourage institutionalization processes. The results of the design analysis used as the basis of the revision are expected to be implemented by the teacher in the teaching experiment.

Growth and characterization of dichlorobis L-proline Zn(II): A semiorganic nonlinear optical single crystal

Science.gov (United States)

Lydia Caroline, M.; Kandasamy, A.; Mohan, R.; Vasudevan, S.

2009-02-01

A semiorganic nonlinear optical material dichlorobis L-proline Zn (II) (DBLPZ), with molecular formula [ZnCl 2(C 5H 9NO 2) 2], has been synthesized from mixed solvents of deionised water and methanol. Single crystals of DBLPZ were successfully grown by the slow evaporation method at an ambient temperature. Single-crystal X-ray diffractometer was utilized to measure unit cell parameters and to confirm the crystal structure. The powder X-ray diffraction pattern of the grown DBLPZ has been indexed. The modes of vibration of different molecular groups present in the sample were identified by the FTIR spectral analysis. The optical transmittance window and the lower cutoff wavelength of the DBLPZ have been identified by UV-vis-NIR studies. Thermal stability of the DBLPZ was determined from TG/DTA/DSC curves, which indicate that the material is stable up to 242.3 °C. The existence of second harmonic generation signals was observed using Nd:YAG laser with fundamental wavelength of 1064 nm possessing SHG efficiency of 0.5 times of KDP and hence it can be a potential material for the frequency-doubling process.

Usefulness of multi-plane dynamic subtraction CT (MPDS-CT) for intracranial high density lesions

Energy Technology Data Exchange (ETDEWEB)

Takagi, Ryo; Kumazaki, Tatsuo [Nippon Medical School, Tokyo (Japan)

1996-02-01

We present a new CT technique using the high speed CT scanner in detection and evaluation of temporal and spatial contrast enhancement of intracranial high density lesions. A multi-plane dynamic subtraction CT (MPDS-CT) was performed in 21 patients with intracranial high density lesions. These lesions consisted of 10 brain tumors, 7 intracerebral hemorrhages and 4 vascular malformations (2 untreated, 2 post-embolization). Baseline study was first performed, and 5 sequential planes of covering total high density lesions were selected. After obtaining the 5 sequential CT images as mask images, three series of multi-plane dynamic CT were performed for the same 5 planes with an intravenous bolus injection of contrast medium. MPDS-CT images were reconstructed by subtracting dynamic CT images from the mask ones. MPDS-CT were compared with conventional contrast-enhanced CT. MPDS-CT images showed the definite contrast enhancement of high density brain tumors and vascular malformations which were not clearly identified on conventional contrast-enhanced CT images because of calcified or hemorrhagic lesions and embolic materials, enabling us to eliminate enhanced abnormalities with non-enhanced areas such as unusual intracerebral hemorrhages. MPDS-CT will provide us further accurate and objective information and will be greatly helpful for interpreting pathophysiologic condition. (author).

Assessment of blood supply to intracranial pathologies in children using MR digital subtraction angiography

Energy Technology Data Exchange (ETDEWEB)

Chooi, Weng Kong; Coley, Stuart C. [Royal Hallamshire Hospital, Department of Radiology, Sheffield (United Kingdom); Connolly, Dan J.A. [Royal Hallamshire Hospital, Department of Radiology, Sheffield (United Kingdom); Sheffield Children' s Hospital, Department of Radiology, Sheffield (United Kingdom); Griffiths, Paul D. [Royal Hallamshire Hospital, Department of Radiology, Sheffield (United Kingdom); Sheffield Children' s Hospital, Department of Radiology, Sheffield (United Kingdom); University of Sheffield, Academic Unit of Radiology, Sheffield (United Kingdom); Floor C, Royal Hallamshire Hospital, Section of Academic Radiology, Sheffield (United Kingdom)

2006-10-15

MR digital subtraction angiography (MR-DSA) is a contrast-enhanced MR angiographic sequence that enables time-resolved evaluation of the cerebral circulation. We describe the feasibility and technical success of our attempts at MR-DSA for the assessment of intracranial pathology in children. We performed MR-DSA in 15 children (age range 5 days to 16 years) referred for MR imaging because of known or suspected intracranial pathology that required a dynamic assessment of the cerebral vasculature. MR-DSA consisted of a thick (6-10 mm) slice-selective RF-spoiled fast gradient-echo sequence (RF-FAST) acquired before and during passage of an intravenously administered bolus of Gd-DTPA. The images were subtracted and viewed as a cine loop. MR-DSA was performed successfully in all patients. High-flow lesions were shown in four patients; these included vein of Galen aneurysmal malformation, dural fistula, and two partially treated arteriovenous malformations (AVMs). Low-flow lesions were seen in three patients, all of which were tumours. Normal flow was confirmed in eight patients including two with successfully treated AVMs, and in three patients with cavernomas. Our early experience suggests that MR-DSA is a realistic, non-invasive alternative to catheter angiography in certain clinical settings. (orig.)

Assessment of blood supply to intracranial pathologies in children using MR digital subtraction angiography

International Nuclear Information System (INIS)

Chooi, Weng Kong; Coley, Stuart C.; Connolly, Dan J.A.; Griffiths, Paul D.

2006-01-01

MR digital subtraction angiography (MR-DSA) is a contrast-enhanced MR angiographic sequence that enables time-resolved evaluation of the cerebral circulation. We describe the feasibility and technical success of our attempts at MR-DSA for the assessment of intracranial pathology in children. We performed MR-DSA in 15 children (age range 5 days to 16 years) referred for MR imaging because of known or suspected intracranial pathology that required a dynamic assessment of the cerebral vasculature. MR-DSA consisted of a thick (6-10 mm) slice-selective RF-spoiled fast gradient-echo sequence (RF-FAST) acquired before and during passage of an intravenously administered bolus of Gd-DTPA. The images were subtracted and viewed as a cine loop. MR-DSA was performed successfully in all patients. High-flow lesions were shown in four patients; these included vein of Galen aneurysmal malformation, dural fistula, and two partially treated arteriovenous malformations (AVMs). Low-flow lesions were seen in three patients, all of which were tumours. Normal flow was confirmed in eight patients including two with successfully treated AVMs, and in three patients with cavernomas. Our early experience suggests that MR-DSA is a realistic, non-invasive alternative to catheter angiography in certain clinical settings. (orig.)

Assessment of blood supply to intracranial pathologies in children using MR digital subtraction angiography.

Science.gov (United States)

Chooi, Weng Kong; Connolly, Dan J A; Coley, Stuart C; Griffiths, Paul D

2006-10-01

MR digital subtraction angiography (MR-DSA) is a contrast-enhanced MR angiographic sequence that enables time-resolved evaluation of the cerebral circulation. We describe the feasibility and technical success of our attempts at MR-DSA for the assessment of intracranial pathology in children. We performed MR-DSA in 15 children (age range 5 days to 16 years) referred for MR imaging because of known or suspected intracranial pathology that required a dynamic assessment of the cerebral vasculature. MR-DSA consisted of a thick (6-10 mm) slice-selective RF-spoiled fast gradient-echo sequence (RF-FAST) acquired before and during passage of an intravenously administered bolus of Gd-DTPA. The images were subtracted and viewed as a cine loop. MR-DSA was performed successfully in all patients. High-flow lesions were shown in four patients; these included vein of Galen aneurysmal malformation, dural fistula, and two partially treated arteriovenous malformations (AVMs). Low-flow lesions were seen in three patients, all of which were tumours. Normal flow was confirmed in eight patients including two with successfully treated AVMs, and in three patients with cavernomas. Our early experience suggests that MR-DSA is a realistic, non-invasive alternative to catheter angiography in certain clinical settings.

Identification of immune response-related genes in the Chinese oak silkworm, Antheraea pernyi by suppression subtractive hybridization.

Science.gov (United States)

Liu, Qiu-Ning; Zhu, Bao-Jian; Wang, Lei; Wei, Guo-Qing; Dai, Li-Shang; Lin, Kun-Zhang; Sun, Yu; Qiu, Jian-Feng; Fu, Wei-Wei; Liu, Chao-Liang

2013-11-01

Insects possess an innate immune system that responds to invading microorganisms. In this study, a subtractive cDNA library was constructed to screen for immune response-related genes in the fat bodies of Antheraea pernyi (Lepidoptera: Saturniidae) pupa challenged with Escherichia coli. Four hundred putative EST clones were identified by suppression subtractive hybridization (SSH), including 50 immune response-related genes, three cytoskeleton genes, eight cell cycle and apoptosis genes, five respiration and energy metabolism genes, five transport genes, 40 metabolism genes, ten stress response genes, four transcription and translation regulation genes and 77 unknown genes. To verify the reliability of the SSH data, the transcription of a set of randomly selected immune response-related genes were confirmed by semi-quantitative reverse transcription-PCR (RT-PCR) and real-time quantitative reverse transcription-PCR (qRT-PCR). These identified immune response-related genes provide insight into understanding the innate immunity in A. pernyi. Copyright © 2013 Elsevier Inc. All rights reserved.

Cloning the Gravity and Shear Stress Related Genes from MG-63 Cells by Subtracting Hybridization

Science.gov (United States)

Zhang, Shu; Dai, Zhong-quan; Wang, Bing; Cao, Xin-sheng; Li, Ying-hui; Sun, Xi-qing

2008-06-01

Background The purpose of the present study was to clone the gravity and shear stress related genes from osteoblast-like human osteosarcoma MG-63 cells by subtractive hybridization. Method MG-63 cells were divided into two groups (1G group and simulated microgravity group). After cultured for 60 h in two different gravitational environments, two groups of MG-63 cells were treated with 1.5Pa fluid shear stress (FSS) for 60 min, respectively. The total RNA in cells was isolated. The gravity and shear stress related genes were cloned by subtractive hybridization. Result 200 clones were gained. 30 positive clones were selected using PCR method based on the primers of vector and sequenced. The obtained sequences were analyzed by blast. changes of 17 sequences were confirmed by RT-PCR and these genes are related to cell proliferation, cell differentiation, protein synthesis, signal transduction and apoptosis. 5 unknown genes related to gravity and shear stress were found. Conclusion In this part of our study, our result indicates that simulated microgravity may change the activities of MG-63 cells by inducing the functional alterations of specific genes.

A System based on Adaptive Background Subtraction Approach for Moving Object Detection and Tracking in Videos

Directory of Open Access Journals (Sweden)

Bahadır KARASULU

2013-04-01

Full Text Available Video surveillance systems are based on video and image processing research areas in the scope of computer science. Video processing covers various methods which are used to browse the changes in existing scene for specific video. Nowadays, video processing is one of the important areas of computer science. Two-dimensional videos are used to apply various segmentation and object detection and tracking processes which exists in multimedia content-based indexing, information retrieval, visual and distributed cross-camera surveillance systems, people tracking, traffic tracking and similar applications. Background subtraction (BS approach is a frequently used method for moving object detection and tracking. In the literature, there exist similar methods for this issue. In this research study, it is proposed to provide a more efficient method which is an addition to existing methods. According to model which is produced by using adaptive background subtraction (ABS, an object detection and tracking system’s software is implemented in computer environment. The performance of developed system is tested via experimental works with related video datasets. The experimental results and discussion are given in the study

Single-loop renormalizations and properties of radiative corrections in the Fried-Yennie gauge

International Nuclear Information System (INIS)

Karshenboim, S.G.; Shelyuto, V.A.; Eides, M.I.

1988-01-01

Single-loop radiative corrections are studied in the Fried-Yennie gauge. It is shown that in this gauge the usual subtraction procedure on the mass shell does not require introduction of an infrared photon mass. The behavior of the diagrams containing radiative corrections near the mass shell is investigated, and it is shown that in the Fried-Yennie gauge this behavior is softer than in any other gauge and softer than the behavior of the corresponding graphs without radiative corrections

Cryo-imaging of fluorescently labeled single cells in a mouse

Science.gov (United States)

Steyer, Grant J.; Roy, Debashish; Salvado, Olivier; Stone, Meredith E.; Wilson, David L.

2009-02-01

We developed a cryo-imaging system to provide single-cell detection of fluorescently labeled cells in mouse, with particular applicability to stem cells and metastatic cancer. The Case cryoimaging system consists of a fluorescence microscope, robotic imaging positioner, customized cryostat, PC-based control system, and visualization/analysis software. The system alternates between sectioning (10-40 μm) and imaging, collecting color brightfield and fluorescent blockface image volumes >60GB. In mouse experiments, we imaged quantum-dot labeled stem cells, GFP-labeled cancer and stem cells, and cell-size fluorescent microspheres. To remove subsurface fluorescence, we used a simplified model of light-tissue interaction whereby the next image was scaled, blurred, and subtracted from the current image. We estimated scaling and blurring parameters by minimizing entropy of subtracted images. Tissue specific attenuation parameters were found [uT : heart (267 +/- 47.6 μm), liver (218 +/- 27.1 μm), brain (161 +/- 27.4 μm)] to be within the range of estimates in the literature. "Next image" processing removed subsurface fluorescence equally well across multiple tissues (brain, kidney, liver, adipose tissue, etc.), and analysis of 200 microsphere images in the brain gave 97+/-2% reduction of subsurface fluorescence. Fluorescent signals were determined to arise from single cells based upon geometric and integrated intensity measurements. Next image processing greatly improved axial resolution, enabled high quality 3D volume renderings, and improved enumeration of single cells with connected component analysis by up to 24%. Analysis of image volumes identified metastatic cancer sites, found homing of stem cells to injury sites, and showed microsphere distribution correlated with blood flow patterns. We developed and evaluated cryo-imaging to provide single-cell detection of fluorescently labeled cells in mouse. Our cryo-imaging system provides extreme (>60GB), micron

Genomic Diversity of Burkholderia pseudomallei Clinical Isolates: Subtractive Hybridization Reveals a Burkholderia mallei-Specific Propage in B. pseudomallei 1026b

National Research Council Canada - National Science Library

DeShazer, David

2004-01-01

.... pseudomallei, 1026b and K96243. Numerous mobile genetic elements, including a temperate bacteriophage designated phi1026b, were identified among the 1026b-specific suppression subtractive hybridization products...

Single Electron Transistor Platform for Microgravity Proteomics, Phase II

Data.gov (United States)

National Aeronautics and Space Administration — This Phase II program builds from the successful Phase I efforts to demonstrate that Quantum Logic Devices' nanoelectronic platform for biological detection could...

Mycotic aneurysms in intravenous drug abusers: the utility of intravenous digital subtraction angiography

International Nuclear Information System (INIS)

Shetty, P.C.; Krasicky, G.A.; Sharma, R.P.; Vemuri, B.R.; Burke, M.M.

1985-01-01

Two-hundred thirteen intravenous digital subtraction angiographic (DSA) examinations were performed on 195 intravenous drug abusers to rule out the possibility of a mycotic aneurysm in a groin, neck, or upper extremity infection. Twenty-three surgically proved cases of mycotic aneurysm were correctly identified with no false positive results. In addition, six cases of major venous occlusion were documented. The authors present the results of their experience and conclude that DSA is an effective and cost-efficient method of examining this high risk patient population

Theoretical study of diaquamalonatozinc(II) single crystal for applications in non-linear optical devices

Science.gov (United States)

Chakraborty, Mitesh; Rai, Vineet Kumar

2017-12-01

The aim of the present paper is to employ theoretical methods to investigate the zero field splitting (ZFS) parameter and to investigate the position of the dopant in the host. These theoretical calculations have been compared with the empirical results. The superposition model (SPM) with the microscopic spin-Hamiltonian (MSH) theory and the coefficient of fractional parentage have been employed to investigate the dopant manganese(II) ion substitution in the diaquamalonatozinc(II) (DAMZ) single crystal. The magnetic parameters, viz. g-tensor and D-tensor, has been determined by using the ORCA program package developed by F Neese et al. The unrestricted Kohn-Sham orbitals-based Pederson-Khanna (PK) as the unperturbed wave function is observed to be the most suitable for the computational calculation of spin-orbit tensor (D^{SO}) of the axial ZFS parameter D. The effects of spin-spin dipolar couplings are taken into account. The unrestricted natural orbital (UNO) is used for the calculation of spin-spin dipolar contributions to the ZFS tensor. A comparative study of the quantum mechanical treatment of Pederson-Khanna (PK) with coupled perturbation (CP) is reported in the present study. The unrestricted Kohn-Sham-based natural orbital with Pederson-Khanna-type of perturbation approach validates the experimental results in the evaluation of ZFS parameters. The theoretical results are appropriate with the experimental ones and indicate the interstitial occupancy of Mn^{2+} ion in the host matrix.

Detection of a possible epilepsy focus in a preoperated patient by perfusion SPECT and computer-aided subtraction analysis

International Nuclear Information System (INIS)

Apostolova, I.; Wilke, F.; Clausen, M.; Buchert, R.; Lindenau, M.; Stodieck, S.; Fiehler, J.; Heese, O.

2008-01-01

Ictal perfusion SPECT with either 9 9mTc-hexamethylpropylene amine oxime (HMPAO) or 9 9mTc-ethylcysteinate dimer (ECD) has been reported to provide very good sensitivity for the determination of the SOA in fTLE. Sensitivity of interictal perfusion SPECT is much lower. However, interictal perfusion SPECT might enhance the specificity of ictal SPECT findings by improving the discrimination between seizure related local hyperperfusion and intersubject variability of perfusion (physiologic hyperperfusion). In addition, the combination of interictal and ictal perfusion SPECT might provide improved sensitivity compared to ictal SPECT alone, particularly when computer-aided subtraction of ictal and interictal SPECT is used instead of traditional side-by-side visual comparison. The combination of ictal and interictal perfusion SPECT eliminates not only physiological inter-subject variance, but it can also eliminate severe partial volume effects. Computer-aided subtraction analysis appears particularly useful in this case

Detection of a possible epilepsy focus in a preoperated patient by perfusion SPECT and computer-aided subtraction analysis

Energy Technology Data Exchange (ETDEWEB)

Apostolova, I.; Wilke, F.; Clausen, M.; Buchert, R. [Univ. Medical Center Hamburg-Eppendorf (Germany). Dept. of Nuclear Medicine; Lindenau, M.; Stodieck, S. [Protestant Hospital Alsterdorf, Hamburg (Germany). Dept. of Neurology and Epileptology; Fiehler, J. [Univ. Medical Center Hamburg-Eppendorf (Germany). Dept. of Neuroradiology; Heese, O. [Univ. Medical Center Hamburg-Eppendorf (Germany). Neurological Surgery

2008-07-01

Ictal perfusion SPECT with either {sup 9}9mTc-hexamethylpropylene amine oxime (HMPAO) or {sup 9}9mTc-ethylcysteinate dimer (ECD) has been reported to provide very good sensitivity for the determination of the SOA in fTLE. Sensitivity of interictal perfusion SPECT is much lower. However, interictal perfusion SPECT might enhance the specificity of ictal SPECT findings by improving the discrimination between seizure related local hyperperfusion and intersubject variability of perfusion (physiologic hyperperfusion). In addition, the combination of interictal and ictal perfusion SPECT might provide improved sensitivity compared to ictal SPECT alone, particularly when computer-aided subtraction of ictal and interictal SPECT is used instead of traditional side-by-side visual comparison. The combination of ictal and interictal perfusion SPECT eliminates not only physiological inter-subject variance, but it can also eliminate severe partial volume effects. Computer-aided subtraction analysis appears particularly useful in this case.

TU-CD-207-03: Time Evolution of Texture Parameters of Subtracted Images Obtained by Contrast-Enhanced Digital Mammography (CEDM)

Energy Technology Data Exchange (ETDEWEB)

Mateos, M-J; Brandan, M-E [Instituto de Fisica, Universidad Nacional Autonom de Mexico, Mexico, Distrito Federal (Mexico); Gastelum, A; Marquez, J [Centro de Ciencias Aplicadas y Desarrollo Tecnologico Universidad Nacional Autonoma de Mexico, Mexico, Distrito Federal (Mexico)

2015-06-15

Purpose: To evaluate the time evolution of texture parameters, based on the gray level co-occurrence matrix (GLCM), in subtracted images of 17 patients (10 malignant and 7 benign) subjected to contrast-enhanced digital mammography (CEDM). The goal is to determine the sensitivity of texture to iodine uptake at the lesion, and its correlation (or lack of) with mean-pixel-value (MPV). Methods: Acquisition of clinical images followed a single-energy CEDM protocol using Rh/Rh/48 kV plus external 0.5 cm Al from a Senographe DS unit. Prior to the iodine-based contrast medium (CM) administration a mask image was acquired; four CM images were obtained 1, 2, 3, and 5 minutes after CM injection. Temporal series were obtained by logarithmic subtraction of registered CM minus mask images.Regions of interest (ROI) for the lesion were drawn by a radiologist and the texture was analyzed. GLCM was evaluated at a 3 pixel distance, 0° angle, and 64 gray-levels. Pixels identified as registration errors were excluded from the computation. 17 texture parameters were chosen, classified according to similarity into 7 groups, and analyzed. Results: In all cases the texture parameters within a group have similar dynamic behavior. Two texture groups (associated to cluster and sum mean) show a strong correlation with MPV; their average correlation coefficient (ACC) is r{sup 2}=0.90. Other two groups (contrast, homogeneity) remain constant with time, that is, a low-sensitivity to CM uptake. Three groups (regularity, lacunarity and diagonal moment) are sensitive to CM uptake but less correlated with MPV; their ACC is r{sup 2}=0.78. Conclusion: This analysis has shown that, at least groups associated to regularity, lacunarity and diagonal moment offer dynamical information additional to the mean pixel value due to the presence of CM at the lesion. The next step will be the analysis in terms of the lesion pathology. Authors thank PAPIIT-IN105813 for support. Consejo Nacional de Ciencia Y

Parametric Imaging Of Digital Subtraction Angiography Studies For Renal Transplant Evaluation

Science.gov (United States)

Gallagher, Joe H.; Meaney, Thomas F.; Flechner, Stuart M.; Novick, Andrew C.; Buonocore, Edward

1981-11-01

A noninvasive method for diagnosing acute tubular necrosis and rejection would be an important tool for the management of renal transplant patients. From a sequence of digital subtraction angiographic images acquired after an intravenous injection of radiographic contrast material, the parametric images of the maximum contrast, the time when the maximum contrast is reached, and two times the time at which one half of the maximum contrast is reached are computed. The parametric images of the time when the maximum is reached clearly distinguish normal from abnormal renal function. However, it is the parametric image of two times the time when one half of the maximum is reached which provides some assistance in differentiating acute tubular necrosis from rejection.

Radiation doses to patients from digital subtraction angiography

International Nuclear Information System (INIS)

Goni, H.; Tsalafoutas, I. A.; Tzortzis, G.; Pappas, P.; Bouzas, N.; Loulakas, J.; Georgiou, A.; Georgiou, E.; Yakoumakis, E. N.

2005-01-01

This investigation determined patient doses during digital subtraction angiography (DSA). Fluoroscopy time, dose-area product (DAP) and entrance surface air kerma (ESAK) were analysed from 263 DSA examinations, classified into seven categories: (1) abdominal aorta, iliac, femoral, popliteal and leg arteries; (2) abdominal aorta and super-selective DSA of renal arteries; (3) combination of (1) and (2); (4) super-selective DSA of common carotid and vertebral arteries, intracranial branches in face and profile projections; (5) super-selective DSA of hepatic, splenic, superior and inferior mesenteric arteries; (6) combination of (1) and (4); and (7) celiac trunk and branches. Median DAP values were 67.7, 92.9, 76.6, 53.6, 105.7, 76.1 and 2.6 Gy cm 2 , respectively. With the exception of one examination, ESAK values were below 2 Gy: the limit for erythema. Compared with published data, DAP values were within the range reported for (1) and (4), slightly larger for (2) and (5), whereas no references were identified for the remaining three categories. (authors)

Isolation of differentially expressed sex genes in garden asparagus using suppression subtractive hybridization.

Science.gov (United States)

Deng, Chuan-liang; Wang, Ning-na; Li, Shu-fen; Dong, Tian-yu; Zhao, Xin-peng; Wang, Shao-jing; Gao, Wu-jun; Lu, Long-dou

2015-09-01

Garden asparagus (Asparagus officinalis L.) is a dioecious species whose male and female flowers are found in separate unisexual individuals. A region called the M-locus, located on a pair of homomorphic sex chromosomes, controls sexual dimorphism in asparagus. To date, no sex determining gene has been isolated from asparagus. To identify more genes involved in flower development in asparagus, subtractive hybridization library of male flowers in asparagus was constructed by suppression subtraction hybridization. A total of 107 expressed sequence tags (ESTs) were identified. BLASTX analysis showed that the library contained several genes that could be related to flower development. The expression patterns of seven selected genes believed to be involved in the development of asparagus male flower were further analyzed by semi-quantitative or real-time reverse-transcription polymerase chain reaction (RT-PCR). Results showed that AOEST4-5, AOEST12-40, and AOEST13-38 were strongly expressed in the male flower stage, whereas no transcript level of AOEST13-38 was detected in the female flower stage. The expression levels of AOEST13-87, AOEST13-92, AOEST13-40, and AOEST18-87 in the male flower stage were also higher than those in the female flower stage, although these transcripts were also expressed in other tissues. The identified genes can provide a strong starting point for further studies on the underlying molecular differences between the male and female flowers of asparagus.

Digital subtraction angiography with an Isocon camera system: clinical applications

International Nuclear Information System (INIS)

Barbaric, Z.L.; Gomes, A.S.; Deckard, M.E.; Nelson, R.S.; Moler, C.L.

1984-01-01

A new imaging system for digital subtraction angiography (DSA) was evaluated in 30 clinical studies. The image receptor is a 25 X 25 cm, 12 par gadolinium oxysulfate rare-earth screen whose light output is focused to a low-light-level Isocon camera. The video signal is digitized and processed by an image-array processor containing 31 512 X 512 memories 8 bits deep. In most patients, intraarterial DSA studies were done in conjunction with conventional arteriography. In these arterial studies, images adequate to make a specific diagnosis were obtained using half the radiation dose and half the amount of contrast material needed for conventional angiography. In eight intravenous studies performed either to identify renal artery stenosis or for evaluation of congenital heart anomalies, the images were diagnostic but objectionably noisy

A revision of the subtract-with-borrow random number generators

Science.gov (United States)

Sibidanov, Alexei

2017-12-01

The most popular and widely used subtract-with-borrow generator, also known as RANLUX, is reimplemented as a linear congruential generator using large integer arithmetic with the modulus size of 576 bits. Modern computers, as well as the specific structure of the modulus inferred from RANLUX, allow for the development of a fast modular multiplication - the core of the procedure. This was previously believed to be slow and have too high cost in terms of computing resources. Our tests show a significant gain in generation speed which is comparable with other fast, high quality random number generators. An additional feature is the fast skipping of generator states leading to a seeding scheme which guarantees the uniqueness of random number sequences. Licensing provisions: GPLv3 Programming language: C++, C, Assembler