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Sample records for single spermatogonia supports

  1. Radiation-induced DNA single-strand scission and its rejoining in spermatogonia and spermatozoa of mouse

    International Nuclear Information System (INIS)

    Ono, T.; Okada, S.

    1977-01-01

    Gamma-ray-induced DNA single-strand scissions and the ability to repair the scissions in spermatogonia from young mice and in spermatozoa from adult mice were studied quantitatively by an alkaline sucrose density-gradient centrifugation method. The average size of DNAs in non-irradiated spermatogonia was 2.6-3.0xx10 8 daltons, similar to those of a spermatid-rich population, and the size of DNA in non-irradiated spermatozoa was 1.2x10 8 daltons. In spermatogonia, the radiosensitivity of DNA was 0.42 single-strand breaks/10 12 daltons of DNA/rad in oxic conditions and only 0.24 under anoxic conditions. In spermatozoa the break efficiency of DNA was 0.22 single-strand breaks/10 12 daltons of DNA/rad under oxic conditions and altered little under anoxic irradiation. The DNA scissions were efficiently repaired in spermatogonia within 10 min, whereas the breaks in spermatozoa were not rejoined at all even after two days of post-irradiation time. The radiosensitivities of DNA, repair capability and non- and/or slowreparable DNA scissions were compared in spermatogonium-rich, spermatid-rich and spermatozoanrich populations

  2. In vivo dynamics of GFRα1-positive spermatogonia stimulated by GDNF signals using a bead transplantation assay

    Energy Technology Data Exchange (ETDEWEB)

    Uchida, Aya; Kishi, Kasane; Aiyama, Yoshimi; Miura, Kento [Department of Veterinary Anatomy, The University of Tokyo, Yayoi, Tokyo, 113-8657 (Japan); Takase, Hinako M.; Suzuki, Hitomi; Kanai-Azuma, Masami [Department of Experimental Animal Model for Human Disease, Tokyo Medical and Dental University, Tokyo, 113-8510 (Japan); Iwamori, Tokuko [Center of Biomedical Research, Kyusyu University, Fukuoka, 812-8582 (Japan); Kurohmaru, Masamichi; Tsunekawa, Naoki [Department of Veterinary Anatomy, The University of Tokyo, Yayoi, Tokyo, 113-8657 (Japan); Kanai, Yoshiakira, E-mail: aykanai@mail.ecc.u-tokyo.ac.jp [Department of Veterinary Anatomy, The University of Tokyo, Yayoi, Tokyo, 113-8657 (Japan)

    2016-08-05

    In mouse testes, spermatogonial stem cells (SSCs), a subpopulation of GFRα1 (GDNF family receptor-α1)-positive spermatogonia, are widely distributed along the convoluted seminiferous tubules. The proliferation and differentiation of the SSCs are regulated in part by local expression of GDNF (glial cell-derived neurotorphic factor), one of major niche factors for SSCs. However, the in vivo dynamics of the GDNF-stimulated GFRα1-positive spermatogonia remains unclear. Here, we developed a simple method for transplanting DiI-labeled and GDNF-soaked beads into the mouse testicular interstitium. By using this method, we examined the dynamics of GFRα1-positive spermatogonia in the tubular walls close to the transplanted GDNF-soaked beads. The bead-derived GDNF signals were able to induce the stratified aggregate formation of GFRα1-positive undifferentiated spermatogonia by day 3 post-transplantation. Each aggregate consisted of tightly compacted A{sub single} and marginal A{sub paired}–A{sub aligned} GFRα1-positive spermatogonia and was surrounded by A{sub aligned} GFRα1-negative spermatogonia at more advanced stages. These data not only provide in vivo evidence for the inductive roles of GDNF in forming a rapid aggregation of GFRα1-positive spermatogonia but also indicate the usefulness of this in vivo assay system of various growth factors for the stem/progenitor spermatogonia in mammalian spermatogenesis. - Highlights: • A novel bead transplantation assay was developed to examine the in vivo effects of growth factors on spermatogonia. • A rapid aggregation of GFRα1-positive spermatogonia was induced by the transplanted GDNF-soaked beads. • Tightly-compacted A{sub single} and marginal A{sub paired}–A{sub aligned} spermatogonia were formed in each GFRα1-positive aggregate.

  3. Effects of single and split doses of cobalt-60 gamma rays and 14 MeV neutrons on mouse stem cell spermatogonia.

    Science.gov (United States)

    Hacker-Klom, U B; Köhnlein, W; Göhde, W

    2000-12-01

    The long-term effects of ionizing radiation on male gonads may be the result of damage to spermatogonial stem cells. Doses of 10 cGy to 15 Gy (60)Co gamma rays or 10 cGy to 7 Gy 14 MeV neutrons were given to NMRI mice as single or split doses separated by a 24-h interval. The ratios of haploid spermatids/2c cells and the coefficients of variation of DNA histogram peaks as measures of both the cytocidal and the clastogenic actions of radiation were analyzed by DNA flow cytometry after DAPI staining. The coefficient of variation is not only a statistical examination of the data but is also used here as a measure of residual damage to DNA (i.e. a biological dosimeter). Testicular histology was examined in parallel. At 70 days after irradiation, the relative biological effectiveness for neutrons at 50% survival of spermatogonial stem cells was 3.6 for single doses and 2.8 for split doses. The average coefficient of variation of unirradiated controls of elongated spermatids was doubled when stem cells were irradiated with single doses of approximately 14 Gy (60)Co gamma rays or 3 Gy neutrons and observed 70 days later. Split doses of (60)Co gamma rays were more effective than single doses, doubling DNA dispersion at 7 Gy. No fractionation effect was found with neutrons with coefficients of variation.

  4. Imatinib has deleterious effects on differentiating spermatogonia while sparing spermatogonial stem cell self renewal

    Science.gov (United States)

    Heim, Crystal; Minniear, Kayla; Dann, Christina Tenenhaus

    2011-01-01

    Imatinib mesylate is among a growing number of effective cancer drugs that provide molecularly targeted therapy; however, imatinib causes reproductive defects in rodents. The availability of an in vitro system for screening the effect of drugs on spermatogenesis would be beneficial. The imatinib targets, KIT and platelet-derived growth factor receptor beta (PDGFRB), were shown here to be expressed in “germline stem” (GS) cell cultures that contain spermatogonia, including spermatogonial stem cells (SSCs). GS cell cultures were utilized to determine whether imatinib affects SSC self renewal or differentiation. GS cells grown in imatinib retained self renewal based on multiple assays, including transplantation. However, growth in imatinib led to decreased numbers of differentiated spermatogonia and reduced culture growth consistent with the known requirement for KIT in survival and proliferation of spermatogonia. These results build upon the in vivo studies and support the possibility of utilizing GS cell cultures for preclinical drug tests. PMID:21295132

  5. Effective depth of spermatogonia in man

    International Nuclear Information System (INIS)

    Casey, R.; Jewett, M.A.S.; Facey, R.A.

    1982-01-01

    Dosimetry for sperm cells irradiated by high-energy betas requires precise knowledge of the effective depth of the spermatogonia, and hence the thickness of overlying tissues (scrotum plus tunics)), because beta dose rate changes very rapidly with depth. Measurements were made on 25 volunteers and surgical patients by mechanical caliper during surgery (2), by ultrasound (14), or by both (9), all at 20 deg C air temperature. The tunica albuginea (TA) measured 0.1 mm. The surgical results (TA excluded) were 2.0 mm, σ = 0.3 mm (n = 11). The ultrasound results (TA included) were 2.2 mm,σ = 0.6 mm (n = 23). There was no correlation of scrotal thickness with age (24-83 years) and only a very weak correlation (r = 0.3) with body mass. There was no decrease in scrotal thickness (at 20 deg C) with further warming but there was an increase (to 3.3 mm from 2.3 mm) with chilling before measurement. Ultrasound is shown to be valid for such measurements. (author)

  6. Strain differences in the radiosensitivity of mouse spermatogonia

    CERN Document Server

    Bianchi, M; Hurtado de Catalfo, G; Hendry, J H

    1985-01-01

    The radiosensitivity of spermatogonia was found to be greater by up to a factor of 2 in C3H mice than in B6D2F1 mice, whether assessed for the highly sensitive spermatogonia (types A2 to In) or the much more resistant clonogenic spermatogonia which repopulate tubules. The latter were similarly resistant in the B6D2F1 hybrid and in the DBA2 parent, but were much more sensitive in the C57BL parent strain. A difference in sensitivity by up to a factor of 2 results in a variation by a factor of 10 or more in the level of survival of clonogenic cells after high doses. This variation is also observed when comparing data in the literature from different authors using various strains of mice. Using the radiosensitizer misonidazole, it was shown that hypoxia did not play a major role in the lesser sensitivity demonstrated in B6D2F1 mice. The variation in sensitivity is similar to the range reported in the literature for reciprocal translocations.

  7. Histological versus stereological methods applied at spermatogonia during normal human development

    DEFF Research Database (Denmark)

    Cortes, Dina

    1990-01-01

    The number of spermatogonia per tubular transverse section (S/T), and the percentage of seminiferous tubulus containing spermatogonia (the fertility index (FI] were measured in 40 pairs of normal autopsy testes aged 28 weeks of gestation-40 years. S/T and FI showed similar changes during the whole...... period, and were minimal between 1 and 4 years. The number of spermatogonia per testis (S/testis) and the number of spermatogonia per cm3 testis tissue (S/cm3) were estimated by stereological methods in the same testes. S/T and FI respectively were significantly correlated both to S/testis and S/cm3. So...

  8. In vitro differentiation of rat spermatogonia into round spermatids in tissue culture.

    Science.gov (United States)

    Reda, A; Hou, M; Winton, T R; Chapin, R E; Söder, O; Stukenborg, J-B

    2016-09-01

    Do the organ culture conditions, previously defined for in vitro murine male germ cell differentiation, also result in differentiation of rat spermatogonia into post-meiotic germ cells exhibiting specific markers for haploid germ cells? We demonstrated the differentiation of rat spermatogonia into post-meiotic cells in vitro, with emphasis on exhibiting, protein markers described for round spermatids. Full spermatogenesis in vitro from immature germ cells using an organ culture technique in mice was first reported 5 years ago. However, no studies reporting the differentiation of rat spermatogonia into post-meiotic germ cells exhibiting the characteristic protein expression profile or into functional sperm have been reported. Organ culture of testicular fragments of 5 days postpartum (dpp) neonatal rats was performed for up to 52 days. Evaluation of microscopic morphology, testosterone levels, mRNA and protein expression as measured by RT-qPCR and immunostaining were conducted to monitor germ cell differentiation in vitro. Potential effects of melatonin, Glutamax® medium, retinoic acid and the presence of epidydimal fat tissue on the spermatogenic process were evaluated. A minimum of three biological replicates were performed for all experiments presented in this study. One-way ANOVA, ANOVA on ranks and student's t-test were applied to perform the statistical analysis. Male germ cells, present in testicular tissue pieces grown from 5 dpp rats, exhibited positive protein expression for Acrosin and Crem (cAMP (cyclic adenosine mono phosphate) response element modulator) after 52 days of culture in vitro. Intra-testicular testosterone production could be observed after 3 days of culture, while when epididymal fat tissue was added, spontaneous contractility of cultured seminiferous tubules could be observed after 21 days. However, no supportive effect of the supplementation with any factor or the co-culturing with epididymal fat tissue on germ cell differentiation in

  9. Characteristics of A spermatogonia and preleptotene spermatocytes in the vitamin A-deficient rat testis

    NARCIS (Netherlands)

    van Pelt, A. M.; van Dissel-Emiliani, F. M.; Gaemers, I. C.; van der Burg, M. J.; Tanke, H. J.; de rooij, D. G.

    1995-01-01

    The proliferative activity and other characteristics of germ cells in the vitamin A-deficient (VAD) rat testis were investigated. In the VAD testis, A spermatogonia and preleptotene spermatocytes were found. The A spermatogonia in the VAD testis showed a bromodeoxyuridine (BrdU) labeling index of

  10. Histological versus stereological methods applied at spermatogonia during normal human development

    DEFF Research Database (Denmark)

    Cortes, Dina

    1990-01-01

    The number of spermatogonia per tubular transverse section (S/T), and the percentage of seminiferous tubulus containing spermatogonia (the fertility index (FI] were measured in 40 pairs of normal autopsy testes aged 28 weeks of gestation-40 years. S/T and FI showed similar changes during the whol...

  11. Stem cell activity of type A spermatogonia is seasonally regulated in rainbow trout.

    Science.gov (United States)

    Sato, Mana; Hayashi, Makoto; Yoshizaki, Goro

    2017-06-01

    Spermatogonial stem cells (SSCs) support continuous production of sperm throughout the male's life. However, the biological characteristics of SSCs are poorly understood in animals exhibiting seasonal reproduction, even though most wild animals are seasonal breeders. During the spermiation season in rainbow trout, the lumen of the testes contains only spermatozoa and scattered type A spermatogonia (ASG) along the walls of the testicular lobules. These few remaining ASG, designated "residual ASG," are the only germ cells capable of supporting the next spermatogenesis, suggesting that the residual ASG are true SSCs. However, whether residual ASG can behave as SSCs in any teleost species is unknown. In this study, we attempted to clarify the biological characteristics of SSCs associated with seasonal reproduction in rainbow trout using spermatogonial transplantation. We found that the stem cell activity was clearly regulated seasonally during the annual reproductive cycle. Although the residual ASG exhibited moderate transplantability and colony-forming ability at the beginning of the spermiation season, these parameters decreased dramatically later and remained low until the next spermatogenesis was initiated. Furthermore, no clear correlations were observed between these qualitative changes and previously described morphologic characteristics of ASG or plasma sex steroid levels. Our results suggest that the biological properties of SSC populations in rainbow trout are seasonally regulated by a novel mechanism. © The Authors 2017. Published by Oxford University Press on behalf of Society for the Study of Reproduction. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  12. Long-term culture of undifferentiated spermatogonia isolated from immature and adult bovine testes.

    Science.gov (United States)

    Suyatno; Kitamura, Yuka; Ikeda, Shuntaro; Minami, Naojiro; Yamada, Masayasu; Imai, Hiroshi

    2018-03-01

    Undifferentiated spermatogonia eventually differentiate in the testis to produce haploid sperm. Within this cell population, there is a small number of spermatogonial stem cells (SSCs). SSCs are rare cells in the testis, and their cellular characteristics are poorly understood. Establishment of undifferentiated cell line would provide an indispensable tool for studying their biological nature and spermiogenesis/spermatogenesis in vitro. However, there have been few reports on the long-term culture of undifferentiated spermatogonia in species other than rodents. Here, we report the derivation and long-term in vitro culture of undifferentiated spermatogonia cell lines from immature and adult bovine testes. Cell lines from immature testes were maintained in serum-free culture conditions in the presence of glial-cell-line-derived neurotropic factor (GDNF) and bovine leukemia inhibitory factor (bLIF). These cell lines have embryonic stem (ES)-like cell morphology, express pluripotent-stem-cell-specific and germ-cell-specific markers at the protein and mRNA levels, and contributed to the inner cell mass (ICM) of embryos in the blastocyst stage. Meanwhile, cell lines established from adult testes were maintained in low-serum media in the presence of 6-bromoindirubin-3'-oxime (BIO). These cell lines have characteristics resembling those of previously reported male mouse germ cell lines as confirmed by their botryoidally aggregated morphology, as well as the expression of germ-cell-specific markers and pluripotent stem cell markers. These findings could be useful for the development of long-term culture of undifferentiated spermatogonia, which could aid in conservation of species and improvement of livestock production through genome editing technology. © 2018 Wiley Periodicals, Inc.

  13. The Relation Between Adult Dark Spermatogonia and Other Parameters of Fertility Potential in Cryptorchid Testes

    DEFF Research Database (Denmark)

    Thorup, Jørgen Mogens; Kvist, Kolja; Clasen-Linde, Erik

    2013-01-01

    The fertility potential of boys with cryptorchidism may be related to the number of adult dark spermatogonia per tubular transverse section in testicular biopsies taken at orchiopexy. Placental-like alkaline phosphatase positive gonocytes in testes within year 1 of life indicate preserved ability...... for germ cell transformation. We related these parameters to the total number of tubular germ cells and other factors associated with fertility potential....

  14. Molecular Mechanisms Elicited by d-Aspartate in Leydig Cells and Spermatogonia

    OpenAIRE

    Maria Maddalena Di Fiore; Alessandra Santillo; Sara Falvo; Salvatore Longobardi; Gabriella Chieffi Baccari

    2016-01-01

    A bulk of evidence suggests that d-aspartate (d-Asp) regulates steroidogenesis and spermatogenesis in vertebrate testes. This review article focuses on intracellular signaling mechanisms elicited by d-Asp possibly via binding to the N-methyl-d-aspartate receptor (NMDAR) in both Leydig cells, and spermatogonia. In Leydig cells, the amino acid upregulates androgen production by eliciting the adenylate cyclase-cAMP and/or mitogen-activated protein kinase (MAPK) pathways. d-Asp treatment enhances...

  15. Expression of arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells.

    Directory of Open Access Journals (Sweden)

    Michelle L Churchman

    2011-07-01

    Full Text Available The mammalian Cdkn2a (Ink4a-Arf locus encodes two tumor suppressor proteins (p16(Ink4a and p19(Arf that respectively enforce the anti-proliferative functions of the retinoblastoma protein (Rb and the p53 transcription factor in response to oncogenic stress. Although p19(Arf is not normally detected in tissues of young adult mice, a notable exception occurs in the male germ line, where Arf is expressed in spermatogonia, but not in meiotic spermatocytes arising from them. Unlike other contexts in which the induction of Arf potently inhibits cell proliferation, expression of p19(Arf in spermatogonia does not interfere with mitotic cell division. Instead, inactivation of Arf triggers germ cell-autonomous, p53-dependent apoptosis of primary spermatocytes in late meiotic prophase, resulting in reduced sperm production. Arf deficiency also causes premature, elevated, and persistent accumulation of the phosphorylated histone variant H2AX, reduces numbers of chromosome-associated complexes of Rad51 and Dmc1 recombinases during meiotic prophase, and yields incompletely synapsed autosomes during pachynema. Inactivation of Ink4a increases the fraction of spermatogonia in S-phase and restores sperm numbers in Ink4a-Arf doubly deficient mice but does not abrogate γ-H2AX accumulation in spermatocytes or p53-dependent apoptosis resulting from Arf inactivation. Thus, as opposed to its canonical role as a tumor suppressor in inducing p53-dependent senescence or apoptosis, Arf expression in spermatogonia instead initiates a salutary feed-forward program that prevents p53-dependent apoptosis, contributing to the survival of meiotic male germ cells.

  16. Expression of the pluripotency marker UTF1 is restricted to a subpopulation of early A spermatogonia in rat testis

    NARCIS (Netherlands)

    van Bragt, Maaike P. A.; Roepers-Gajadien, Hermien L.; Korver, Cindy M.; Bogerd, Jan; Okuda, Akihiko; Eggen, Bart J. L.; de Rooij, Dirk G.; van Pelt, Ans M. M.

    The population of early A spermatogonia includes stem cells that possess spermatogonial stern cell properties. Recent reports suggest that these cells have the ability to regain pluripotent properties. Here, we show that expression of the pluripotency marker undifferentiated embryonic cell

  17. Expression of the pluripotency marker UTF1 is restricted to a subpopulation of early A spermatogonia in rat testis

    NARCIS (Netherlands)

    van Bragt, Maaike P. A.; Roepers-Gajadien, Hermien L.; Korver, Cindy M.; Bogerd, Jan; Okuda, Akihiko; Eggen, Bart J. L.; de Rooij, Dirk G.; van Pelt, Ans M. M.

    2008-01-01

    The population of early A spermatogonia includes stem cells that possess spermatogonial stem cell properties. Recent reports suggest that these cells have the ability to regain pluripotent properties. Here, we show that expression of the pluripotency marker undifferentiated embryonic cell

  18. Survival and renewal of murine stem Spermatogonia following 60Co radiation

    International Nuclear Information System (INIS)

    Erickson, B.H.

    1981-01-01

    Spermatogonia, with the exception of the few that are either isolated or paired, exist in clones of varying size, and even though the spermatogonium has been the object of much study, our understanding of the radioresponse of the components of this triumvirate is incomplete. Isolated, paired, and clonal spermatogonia are distinguished most reliably when viewed in segments of seminiferous tubules mounted in toto. Tubular segments were isolated from the testes of 80- to 90-day-old BALB/c mice following irradiation doses of 25 to 800 rad and intervals of 1 to 14 days. Neither isolated nor paired spermatogonia were apparently affected by doses up to 200 rad. In contrast the population of A 1 -spermatogonial clones was markedly reduced by a dose of 25 rad. The D 0 and n for the clone were 217 rad and 0.5, respectively. In the apparent absence of a significant elevation in necrosis at doses of 20 rad and less, the loss of A 1 clones was attributed to mitotic inhibition. The comparative unresponsiveness of the isolated spermatogonium to irradiation, its low mitotic rate when contrasted with the clone's high radiosensitivity and mitotic activity, and its apparent ability to excise an abnormal cell and otherwise fragment to give rise to additional clones led to the tentative conclusion that the clone, and not the isolated spermatogonium, is the stem cell

  19. Tolerance of spermatogonia to oxidative stress is due to high levels of Zn and Cu/Zn superoxide dismutase.

    Directory of Open Access Journals (Sweden)

    Fritzie T Celino

    Full Text Available BACKGROUND: Spermatogonia are highly tolerant to reactive oxygen species (ROS attack while advanced-stage germ cells such as spermatozoa are much more susceptible, but the precise reason for this variation in ROS tolerance remains unknown. METHODOLOGY/PRINCIPAL FINDINGS: Using the Japanese eel testicular culture system that enables a complete spermatogenesis in vitro, we report that advanced-stage germ cells undergo intense apoptosis and exhibit strong signal for 8-hydroxy-2'-deoxyguanosine, an oxidative DNA damage marker, upon exposure to hypoxanthine-generated ROS while spermatogonia remain unaltered. Activity assay of antioxidant enzyme, superoxide dismutase (SOD and Western blot analysis using an anti-Copper/Zinc (Cu/Zn SOD antibody showed a high SOD activity and Cu/Zn SOD protein concentration during early spermatogenesis. Immunohistochemistry showed a strong expression for Cu/Zn SOD in spermatogonia but weak expression in advanced-stage germ cells. Zn deficiency reduced activity of the recombinant eel Cu/Zn SOD protein. Cu/Zn SOD siRNA decreased Cu/Zn SOD expression in spermatogonia and led to increased oxidative damage. CONCLUSIONS/SIGNIFICANCE: These data indicate that the presence of high levels of Cu/Zn SOD and Zn render spermatogonia resistant to ROS, and consequently protected from oxidative stress. These findings provide the biochemical basis for the high tolerance of spermatogonia to oxidative stress.

  20. Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor.

    Directory of Open Access Journals (Sweden)

    Aurore Gely-Pernot

    2015-10-01

    Full Text Available All-trans retinoic acid (ATRA is instrumental to male germ cell differentiation, but its mechanism of action remains elusive. To address this question, we have analyzed the phenotypes of mice lacking, in spermatogonia, all rexinoid receptors (RXRA, RXRB and RXRG or all ATRA receptors (RARA, RARB and RARG. We demonstrate that the combined ablation of RXRA and RXRB in spermatogonia recapitulates the set of defects observed both upon ablation of RAR in spermatogonia. We also show that ATRA activates RAR and RXR bound to a conserved regulatory region to increase expression of the SALL4A transcription factor in spermatogonia. Our results reveal that this major pluripotency gene is a target of ATRA signaling and that RAR/RXR heterodimers are the functional units driving its expression in spermatogonia. They add to the mechanisms through which ATRA promote expression of the KIT tyrosine kinase receptor to trigger a critical step in spermatogonia differentiation. Importantly, they indicate also that meiosis eventually occurs in the absence of a RAR/RXR pathway within germ cells and suggest that instructing this process is either ATRA-independent or requires an ATRA signal originating from Sertoli cells.

  1. Fracture resistance of single-tooth implant-supported

    OpenAIRE

    Piloto, P.A.G.; Piloto, Joana F.

    2014-01-01

    The purpose of this study is to identify and compare the fracture behaviour of the ceramic used in a single-tooth implant-supported. This type of prosthesis is mainly used when a single tooth replacement is needed. Two different materials are tested for the abutment (ceramic and titanium), assuming fully connection to the crown. The implant is made of Titanium. The numerical simulations used the concept of continuous damage mechanics to predict crack pattern when loading the tooth in the vert...

  2. A Community Support Group for Single Custodial Fathers.

    Science.gov (United States)

    Tedder, Sandra L.; And Others

    1981-01-01

    Discusses a five-session group experience within the context of establishing a support group for single custodial fathers. Includes topics of dating, remarriage, homemaking and house maintenance, and the effects of divorce on children. A follow-up showed fathers appreciated the sense of community and specific information and coping strategies.…

  3. A Supportive Service to Single Mothers and Their Children

    Science.gov (United States)

    Heger, Donna Tubach

    1977-01-01

    Describes a supportive program for single, young mothers in need of low-cost housing, job-training or schooling, social services and day care. Most enrollees gained a saleable skill and made progress in personal growth and the development of independent living skills. Techniques included a team approach and use of short-term contracts. (BF)

  4. Compactly supported linearised observables in single-field inflation

    International Nuclear Information System (INIS)

    Fröob, Markus B.; Higuchi, Atsushi; Hack, Thomas-Paul

    2017-01-01

    We investigate the gauge-invariant observables constructed by smearing the graviton and inflaton fields by compactly supported tensors at linear order in general single-field inflation. These observables correspond to gauge-invariant quantities that can be measured locally. In particular, we show that these observables are equivalent to (smeared) local gauge-invariant observables such as the linearised Weyl tensor, which have better infrared properties than the graviton and inflaton fields. Special cases include the equivalence between the compactly supported gauge-invariant graviton observable and the smeared linearised Weyl tensor in Minkowski and de Sitter spaces. Our results indicate that the infrared divergences in the tensor and scalar perturbations in single-field inflation have the same status as in de Sitter space and are both a gauge artefact, in a certain technical sense, at tree level.

  5. Compactly supported linearised observables in single-field inflation

    Energy Technology Data Exchange (ETDEWEB)

    Fröob, Markus B.; Higuchi, Atsushi [Department of Mathematics, University of York, Heslington, York, YO10 5DD (United Kingdom); Hack, Thomas-Paul, E-mail: mbf503@york.ac.uk, E-mail: thomas-paul.hack@itp.uni-leipzig.de, E-mail: atsushi.higuchi@york.ac.uk [Institut für Theoretische Physik, Universität Leipzig, Brüderstraße 16, 04103 Leipzig (Germany)

    2017-07-01

    We investigate the gauge-invariant observables constructed by smearing the graviton and inflaton fields by compactly supported tensors at linear order in general single-field inflation. These observables correspond to gauge-invariant quantities that can be measured locally. In particular, we show that these observables are equivalent to (smeared) local gauge-invariant observables such as the linearised Weyl tensor, which have better infrared properties than the graviton and inflaton fields. Special cases include the equivalence between the compactly supported gauge-invariant graviton observable and the smeared linearised Weyl tensor in Minkowski and de Sitter spaces. Our results indicate that the infrared divergences in the tensor and scalar perturbations in single-field inflation have the same status as in de Sitter space and are both a gauge artefact, in a certain technical sense, at tree level.

  6. OCT2, SSX and SAGE1 reveal the phenotypic heterogeneity of spermatocytic seminoma reflecting distinct subpopulations of spermatogonia

    DEFF Research Database (Denmark)

    Lim, Jasmine; Goriely, Anne; Turner, Gareth Dh

    2011-01-01

    Spermatocytic seminoma (SS) is a rare testicular neoplasm that occurs predominantly in older men. In this study, we aimed to shed light on the histogenesis of SS by investigating the developmental expression of protein markers that identify distinct subpopulations of human spermatogonia in the no...... origin of SS or to partial differentiation during tumour progression, including a hitherto unknown OCT2-positive variant of the tumour likely derived from A(dark) spermatogonia. Copyright © 2011 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd....

  7. γ-Ray-induced reciprocal translocations in spermatogonia of the crab-eating monkey (Macaca fascicularis)

    International Nuclear Information System (INIS)

    Matsuda, Y.; Tobari, I.; Yamagiwa, J.; Utsugi, T.; Kitazume, M.; Nakai, S.

    1984-01-01

    The yield of translocations induced by γ-rays in the crab-eating monkey (Macaca fascicularis) spermatogonia were studied by cytological analysis in spermatocytes derived from them. The frequencies of translocations were 0.09 per cent at 0 Gy, 1.9 per cent at 1 Gy, 2.5 per cent at 2 Gy and 1.3 per cent at 3 Gy, showing a humped dose-response curve with a peak yield around 2 Gy. No remarkable inter-seasonal or inter-animal variations in the induction of translocation were observed. The frequencies in the crab-eating monkey were significantly higher than those in the same Macaca genus, the rhesus monkey (Macaca mulatta). This inter-species difference in radiosensitivity might be affected by the condition of spermatogonial stem cells at the time of exposure to radiation, depending on the seasonal change in spermatogenetic activity. (orig.)

  8. Single directional SMO algorithm for least squares support vector machines.

    Science.gov (United States)

    Shao, Xigao; Wu, Kun; Liao, Bifeng

    2013-01-01

    Working set selection is a major step in decomposition methods for training least squares support vector machines (LS-SVMs). In this paper, a new technique for the selection of working set in sequential minimal optimization- (SMO-) type decomposition methods is proposed. By the new method, we can select a single direction to achieve the convergence of the optimality condition. A simple asymptotic convergence proof for the new algorithm is given. Experimental comparisons demonstrate that the classification accuracy of the new method is not largely different from the existing methods, but the training speed is faster than existing ones.

  9. Single Object Tracking With Fuzzy Least Squares Support Vector Machine.

    Science.gov (United States)

    Zhang, Shunli; Zhao, Sicong; Sui, Yao; Zhang, Li

    2015-12-01

    Single object tracking, in which a target is often initialized manually in the first frame and then is tracked and located automatically in the subsequent frames, is a hot topic in computer vision. The traditional tracking-by-detection framework, which often formulates tracking as a binary classification problem, has been widely applied and achieved great success in single object tracking. However, there are some potential issues in this formulation. For instance, the boundary between the positive and negative training samples is fuzzy, and the objectives of tracking and classification are inconsistent. In this paper, we attempt to address the above issues from the fuzzy system perspective and propose a novel tracking method by formulating tracking as a fuzzy classification problem. First, we introduce the fuzzy strategy into tracking and propose a novel fuzzy tracking framework, which can measure the importance of the training samples by assigning different memberships to them and offer more strict spatial constraints. Second, we develop a fuzzy least squares support vector machine (FLS-SVM) approach and employ it to implement a concrete tracker. In particular, the primal form, dual form, and kernel form of FLS-SVM are analyzed and the corresponding closed-form solutions are derived for efficient realizations. Besides, a least squares regression model is built to control the update adaptively, retaining the robustness of the appearance model. The experimental results demonstrate that our method can achieve comparable or superior performance to many state-of-the-art methods.

  10. Fraksi Heksan dan Fraksi Metanol Ekstrak Biji Pepaya Muda Menghambat Spermatogonia Mencit (Mus Musculus Jantan

    Directory of Open Access Journals (Sweden)

    Bagus Komang Satriyasa

    2010-03-01

    spermatogoniaA decreased significantly (p < 0,01. It is concluded that hexan fraction and methanol fraction ofunripe carica papaya seeds extract can decrease spermatogonia A cell of male mice (mus musculus.

  11. Molecular Mechanisms Elicited by d-Aspartate in Leydig Cells and Spermatogonia.

    Science.gov (United States)

    Di Fiore, Maria Maddalena; Santillo, Alessandra; Falvo, Sara; Longobardi, Salvatore; Chieffi Baccari, Gabriella

    2016-07-14

    A bulk of evidence suggests that d-aspartate (d-Asp) regulates steroidogenesis and spermatogenesis in vertebrate testes. This review article focuses on intracellular signaling mechanisms elicited by d-Asp possibly via binding to the N-methyl-d-aspartate receptor (NMDAR) in both Leydig cells, and spermatogonia. In Leydig cells, the amino acid upregulates androgen production by eliciting the adenylate cyclase-cAMP and/or mitogen-activated protein kinase (MAPK) pathways. d-Asp treatment enhances gene and protein expression of enzymes involved in the steroidogenic cascade. d-Asp also directly affects spermatogonial mitotic activity. In spermatogonial GC-1 cells, d-Asp induces phosphorylation of MAPK and AKT serine-threonine kinase proteins, and stimulates expression of proliferating cell nuclear antigen (PCNA) and aurora kinase B (AURKB). Further stimulation of spermatogonial GC-1 cell proliferation might come from estradiol/estrogen receptor β (ESR2) interaction. d-Asp modulates androgen and estrogen levels as well as the expression of their receptors in the rat epididymis by acting on mRNA levels of Srd5a1 and Cyp19a1 enzymes, hence suggesting involvement in spermatozoa maturation.

  12. Molecular Mechanisms Elicited by d-Aspartate in Leydig Cells and Spermatogonia

    Directory of Open Access Journals (Sweden)

    Maria Maddalena Di Fiore

    2016-07-01

    Full Text Available A bulk of evidence suggests that d-aspartate (d-Asp regulates steroidogenesis and spermatogenesis in vertebrate testes. This review article focuses on intracellular signaling mechanisms elicited by d-Asp possibly via binding to the N-methyl-d-aspartate receptor (NMDAR in both Leydig cells, and spermatogonia. In Leydig cells, the amino acid upregulates androgen production by eliciting the adenylate cyclase-cAMP and/or mitogen-activated protein kinase (MAPK pathways. d-Asp treatment enhances gene and protein expression of enzymes involved in the steroidogenic cascade. d-Asp also directly affects spermatogonial mitotic activity. In spermatogonial GC-1 cells, d-Asp induces phosphorylation of MAPK and AKT serine-threonine kinase proteins, and stimulates expression of proliferating cell nuclear antigen (PCNA and aurora kinase B (AURKB. Further stimulation of spermatogonial GC-1 cell proliferation might come from estradiol/estrogen receptor β (ESR2 interaction. d-Asp modulates androgen and estrogen levels as well as the expression of their receptors in the rat epididymis by acting on mRNA levels of Srd5a1 and Cyp19a1 enzymes, hence suggesting involvement in spermatozoa maturation.

  13. Short implants supporting single crowns in atrophic jaws.

    Science.gov (United States)

    Al-Ansari, Asim

    2014-09-01

    PubMed-Medline, Web of Science, Cochrane Library, ProQuest Dissertations and Theses, LILACS, Ebsco-Dentistry and Oral Sciences Source, Scirus, Embase, Scopus and Journal Ovid databases were searched. In addition hand searching of 14 relevant journals was undertaken along with screening of the reference lists of screened article and reviews. Randomised controlled clinical trials (RCTs), controlled clinical trials (CCTs), prospective cohort studies and case series were included. Studies where short (biological failure proportion (BFP), prosthetic failure proportion (PFP) and radiographic marginal bone loss (MBL) were 5.9% (95% CI: 3.7-9.2%), 3.8% (95%CI: 1.9-7.4%), 2.8% (95%CI: 1.4-5.7%) and 0.83 mm (95%CI: 0.54-1.12 mm) respectively. Quantitative analysis showed that placement in the mandible (p = 0.0002) and implants with length ≤ 8 mm (p = 0.01) increased FP, BFP and MBL, whereas qualitative assessment revealed that crown-to-implant ratio did not influence MBL. Within the limitations of the present systematic review with meta-analysis, it is suggested that single crowns supported by short implants are an acceptable and predictable option in the short- and long-term treatment of the atrophic jaws.

  14. Effect of /sup 60/Co. gamma. radiation on the stem and differentiating spermatogonia of the postpuberal rat

    Energy Technology Data Exchange (ETDEWEB)

    Erickson, B.H.

    1976-12-01

    Previous descriptions of the radioresponse of rodent spermatogonia have relied on schemes of spermatogonial proliferation and differentiation that were either incomplete or inaccurate. This study was undertaken, therefore, to interpret the radioresponse of rat spermatogonia after a currently accepted pattern for their renewal and evolution. Rats were irradiated with /sup 60/Co ..gamma.. radiation at doses varying from 12 to 600 rad at 30 rad/min. Tubules were isolated from Zenker-fixed testes and evaluated according to the method of Huckins (Anat. Rec. 169, 533 (1971)). Stem spermatogonial number was little affected by doses up to 200 rad, and the dose-response curve for this criterion yielded a D/sub 0/ of 373 +- 37 rad and an extrapolation number (n) of 2.1 +- 0.3. Stem-cell mitosis, as reflected by counts of type A/sub 1/ spermatogonia, was, however, substantially affected by a dose of 12 rad and was characterized by a D/sub 0/ of 148 +- 8 rad and an n of 0.5 +- 0.1. The dose required to produce a measurable effect increased as the spermatogonium attained higher states of differentiation. D/sub 0/ and n varied from 139 +- 24 rad and 1.2 +- 0.9, respectively, for type A/sub 1/ to 215 +- 14 rad and 2 +- 0.4 for type A/sub 4/. Due to the extreme lability of its mitosis, the stem spermatogonium appeared to be the weakest link in the chain leading to the spermatozoon.

  15. Controlled growth of single nanowires within a supported alumina template

    DEFF Research Database (Denmark)

    Vlad, A.; Mátéfi-Tempfli, M.; Faniel, S.

    2006-01-01

    A simple technique for fabricating single nanowires with well-defined position is presented. The process implies the use of a silicon nitride mask for selective electrochemical growth of the nanowires in a porous alumina template. We show that this method allows the realization of complex nanowire...

  16. Supporting children after single-incident trauma: parents'views.

    NARCIS (Netherlands)

    Alisic, E.; Boeije, H.R.; Jongmans, M.J.; Kleber, R.J.

    2012-01-01

    Objective. To strengthen trauma-informed health care by exploring parents’ experiences of assisting their child after single-incident trauma (eg, violence, accidents, and sudden loss). Method. Semistructured interviews with parents (N = 33) of 25 exposed children (8-12 years). Results. Responsive

  17. Effect of chlorophyllin on induction of exchanges in sister chromatids by gamma irradiation in mice spermatogonia in vivo

    International Nuclear Information System (INIS)

    Mendiola C, M.T.

    1994-01-01

    Mouse were exposed to different doses of gamma radiation and the effect on Sister Chromatid Exchange (SCE) frequency in spermatogonias was evaluated. The effect was analyzed before and after Bromodeoxyuridine (BrdU) incorporation to determine the interference of such agent with the cellular response induced by radiation. The capacity of chlorophyllin (sodium and Copper salt derivative from chlorophyll) to reduce SCE induction by radiation in normal and BrdU radio sensitized spermatogonia was also determined. The results indicate that there was a significant increase in SCE frequency by gamma radiation exposure in these cells, such effect was higher irradiating after BrdU incorporation than before. This fact confirms previous observations that BrdU sensitizes some cells to SCE induction. With regard to the chlorophyllin effect, it was determined that this salt acts as a radioprotector reducing gamma-rays induced SCE before or after BrdU incorporation Total protection was obtained with 200 μg of chlorophyllin per g of body weight in both protocols. Under the experimental conditions this study there was no evidence of genotoxicity induced by chlorophyllin itself. The results suggest that this agent may act as a radioprotector by scavenging free radicals produced by gamma-radiation which cause DNA lesions that are involved in SCE formation. (Author)

  18. Dose-response relationship of γ-ray-induced reciprocal translocations at low doses in spermatogonia of the crab-eating monkey (Macaca fascicularis)

    International Nuclear Information System (INIS)

    Matsuda, Yoichi; Tobari, Izuo; Yamagiwa, Junji; Utsugi, Toyoko; Okamoto, Masanori; Nakai, Sayaka

    1985-01-01

    The yield of translocations induced by acute γ-irradiation at low doses in the crab-eating monkey's (Macaca fascicularis) spermatogonia was examined. Over the low dose range from 0 to 1 Gy, the dose-response relationship for translocation yield was a linear one. To estimate the sensitivity to the induction of translocations in the crab-eating monkey's spermatogonia, the slope of the regression line was compared with those in other mammalian species. Consequently, over the low dose range below 1 Gy, the sensitivity of the crab-eating monkey's spermatogonia to translocation induction was similar to several mammalian species, the mouse, Chinese hamster, and the rabbit, but significantly higher than that of the rhesus monkey and lower than that of the marmoset. (Auth.)

  19. What Can US Single-Payer Supporters Learn From the Swiss Rejection of Single Payer?

    Science.gov (United States)

    Chaufan, Claudia

    2016-01-01

    On September 27, 2014, Swiss voters rejected a proposal to replace their system of about 60 health insurance companies offering mandatory basic health coverage with a single public insurer, the state, which would offer taxpayer-funded coverage of all medically necessary care. The Swiss and the U.S. media, academia, and business sectors, from conservative and liberal camps, interpreted the results to mean a rejection of single payer and a preference for a privately run system, with important implications for health reform in the United States. While on the surface mainstream interpretations appear reasonable, I argue that they have little basis on fact because they rely on assumptions that, while untrue, are repeated as mantras that conveniently justify the continuation of a model of health insurance that is unraveling, less conspicuously in Switzerland, dramatically in the United States. To make my case, I describe the dominant narrative about Swiss health care and mainstream interpretations of the latest referendum on health reform, unpack the problem within these interpretations, and conclude by identifying what lessons the Swiss referendum contains for single payer advocates in the United States in particular and for those who struggle for social and economic rights more generally. © The Author(s) 2016.

  20. An Investigation of Loneliness and Perceived Social Support Among Single and Partnered Young Adults.

    Science.gov (United States)

    Adamczyk, Katarzyna

    This study investigated the possible differences between single individuals and individuals in nonmarital romantic relationships in the domains of emotional (romantic and family) and social loneliness, and of perceived social support from family, friends and significant others. Based on a Polish university-student sample of 315 participants (167 women and 148 men) aged 19 to 25 years ( M  = 21.90, SD  = 2.15), single relationship status was related to greater romantic and family loneliness, and to less perceived social support from significant others and family. Women reported a lower level of social loneliness and a higher level of perceived social support in comparison to men. Relationship status interacted with gender in predicting perceived social support from significant others and friends. Finally, the duration of remaining single and significant others' support were found to be predictive of single young adults' romantic loneliness. In addition, perceived social support from family and significant others were found to moderate the relationship between the duration of remaining single and romantic loneliness. In particular, high family support and medium-high support from significant others mitigated the negative impact of being single for a long time on romantic loneliness.

  1. Selective alkane activation with single-site atoms on amorphous support

    Science.gov (United States)

    Hock, Adam S.; Schweitzer, Neil M.; Miller, Jeffrey T.; Hu, Bo

    2015-11-24

    The present invention relates generally to catalysts and methods for use in olefin production. More particularly, the present invention relates to novel amorphously supported single-center, Lewis acid metal ions and use of the same as catalysts.

  2. Ventricular assist device support in patients with single ventricles: the Melbourne experience.

    Science.gov (United States)

    Poh, Chin L; Chiletti, Roberto; Zannino, Diana; Brizard, Christian; Konstantinov, Igor E; Horton, Stephen; Millar, Johnny; d'Udekem, Yves

    2017-08-01

    The capacity and limitations of ventricular assist device (VAD) support in single-ventricle physiology remains poorly understood. We aimed to review our experience in the use of VAD support in the single-ventricle circulation to determine its feasibility in this population. We reviewed our experience with VAD support in patients with single ventricles over the past 25 years. Fifty-seven patients received 64 runs of VAD support between 1990 and 2015 at a median age of 13 days [interquartile range (IQR) 4.1-99.4 days], of which 55 were supported for post-cardiotomy failure. The majority of patients received short-term VAD support, while 4 patients were either directly supported (1) or transitioned onto the Berlin Heart EXCOR (3). The median duration of support was 3.5 days (IQR 2.8-5.2 days). Twelve patients suffered significant neurological complications, and thromboembolic events occurred in 8 patients. Twenty-nine of the 55 patients were successfully weaned off support (53%). There were 37 inpatient deaths, with a survival-to-hospital discharge rate of 33% (18 of 55). Of the 4 patients supported after early Fontan failure, 3 died. Having a higher mean arterial blood pressure on initiation of VAD support was the only significant predictor of death (hazards ratio 1.08; 95% confidence interval 1.03-1.14; P = 0.002). Patients who required a second run of support had higher hospital mortality (83% vs 63%; P = 0.84). Of the hospital survivors, 12 patients (63%) remain alive without heart transplantation at median 7.2 years (IQR 3.5-14.0) post VAD support. VAD support in patients with a single ventricle has a high hospital mortality, with 1 of 3 patients surviving to discharge. Systemic VAD support is likely futile in the setting of early Fontan failure or when re-initiation of support is required. © The Author 2017. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

  3. Differential Gene Expression Profiling of Enriched Human Spermatogonia after Short- and Long-Term Culture

    Czech Academy of Sciences Publication Activity Database

    Conrad, S.; Azizi, H.; Hatami, M.; Kubista, Mikael; Bonin, M.; Hennenlotter, J.; Renninger, M.; Skutella, T.

    2014-01-01

    Roč. 2014, č. 138350 (2014) ISSN 2314-6133 Institutional support: RVO:86652036 Keywords : ADULT HUMAN TESTIS * GERM-CELL DEVELOPMENT * HUMAN EMBRYONAL CARCINOMA Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 1.579, year: 2014

  4. Recombinant human albumin supports single cell cloning of CHO cells in chemically defined media.

    Science.gov (United States)

    Zhu, Jiang; Wooh, Jong Wei; Hou, Jeff Jia Cheng; Hughes, Benjamin S; Gray, Peter P; Munro, Trent P

    2012-01-01

    Biologic drugs, such as monoclonal antibodies, are commonly made using mammalian cells in culture. The cell lines used for manufacturing should ideally be clonal, meaning derived from a single cell, which represents a technically challenging process. Fetal bovine serum is often used to support low cell density cultures, however, from a regulatory perspective, it is preferable to avoid animal-derived components to increase process consistency and reduce the risk of contamination from adventitious agents. Chinese hamster ovary (CHO) cells are the most widely used cell line in industry and a large number of serum-free, protein-free, and fully chemically defined growth media are commercially available, although these media alone do not readily support efficient single cell cloning. In this work, we have developed a simple, fully defined, single-cell cloning media, specifically for CHO cells, using commercially available reagents. Our results show that a 1:1 mixture of CD-CHO™ and DMEM/F12 supplemented with 1.5 g/L of recombinant albumin (Albucult®) supports single cell cloning. This formulation can support recovery of single cells in 43% of cultures compared to 62% in the presence of serum. Copyright © 2012 American Institute of Chemical Engineers (AIChE).

  5. Referential ZMP Trajectory for Minimizing Variation of COG Velocity in Single Support Phase of Biped Robot

    Science.gov (United States)

    Sato, Tomoya; Ohnishi, Kouhei

    The referential ZMP (Zero-Moment Point) trajectory that minimizes the variation of COG (Center of Gravity) velocity in the single support phase of a biped robot is shown. Two advantages of using this ZMP trajectory are discussed. The first advantage is that the variation of COG velocity is gradual. The second advantage is that the biped robot enables the heel-contact motion and the toe-off motion in the single support phase. The trajectory planning based on this ZMP trajectory is proposed. In simulation and experiment, the validity of the proposed method was confirmed.

  6. Single-Atom Catalyst of Platinum Supported on Titanium Nitride for Selective Electrochemical Reactions.

    Science.gov (United States)

    Yang, Sungeun; Kim, Jiwhan; Tak, Young Joo; Soon, Aloysius; Lee, Hyunjoo

    2016-02-05

    As a catalyst, single-atom platinum may provide an ideal structure for platinum minimization. Herein, a single-atom catalyst of platinum supported on titanium nitride nanoparticles were successfully prepared with the aid of chlorine ligands. Unlike platinum nanoparticles, the single-atom active sites predominantly produced hydrogen peroxide in the electrochemical oxygen reduction with the highest mass activity reported so far. The electrocatalytic oxidation of small organic molecules, such as formic acid and methanol, also exhibited unique selectivity on the single-atom platinum catalyst. A lack of platinum ensemble sites changed the reaction pathway for the oxygen-reduction reaction toward a two-electron pathway and formic acid oxidation toward direct dehydrogenation, and also induced no activity for the methanol oxidation. This work demonstrates that single-atom platinum can be an efficient electrocatalyst with high mass activity and unique selectivity. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Single wall carbon nanotube supports for portable direct methanol fuel cells.

    Science.gov (United States)

    Girishkumar, G; Hall, Timothy D; Vinodgopal, K; Kamat, Prashant V

    2006-01-12

    Single-wall and multiwall carbon nanotubes are employed as carbon supports in direct methanol fuel cells (DMFC). The morphology and electrochemical activity of single-wall and multiwall carbon nanotubes obtained from different sources have been examined to probe the influence of carbon support on the overall performance of DMFC. The improved activity of the Pt-Ru catalyst dispersed on carbon nanotubes toward methanol oxidation is reflected as a shift in the onset potential and a lower charge transfer resistance at the electrode/electrolyte interface. The evaluation of carbon supports in a passive air breathing DMFC indicates that the observed power density depends on the nature and source of carbon nanostructures. The intrinsic property of the nanotubes, dispersion of the electrocatalyst and the electrochemically active surface area collectively influence the performance of the membrane electrode assembly (MEA). As compared to the commercial carbon black support, single wall carbon nanotubes when employed as the support for anchoring the electrocatalyst particles in the anode and cathode sides of MEA exhibited a approximately 30% enhancement in the power density of a single stack DMFC operating at 70 degrees C.

  8. Nanosheet Supported Single-Metal Atom Bifunctional Catalyst for Overall Water Splitting.

    Science.gov (United States)

    Ling, Chongyi; Shi, Li; Ouyang, Yixin; Zeng, Xiao Cheng; Wang, Jinlan

    2017-08-09

    Nanosheet supported single-atom catalysts (SACs) can make full use of metal atoms and yet entail high selectivity and activity, and bifunctional catalysts can enable higher performance while lowering the cost than two separate unifunctional catalysts. Supported single-atom bifunctional catalysts are therefore of great economic interest and scientific importance. Here, on the basis of first-principles computations, we report a design of the first single-atom bifunctional eletrocatalyst, namely, isolated nickel atom supported on β 12 boron monolayer (Ni 1 /β 12 -BM), to achieve overall water splitting. This nanosheet supported SAC exhibits remarkable electrocatalytic performance with the computed overpotential for oxygen/hydrogen evolution reaction being just 0.40/0.06 V. The ab initio molecular dynamics simulation shows that the SAC can survive up to 800 K elevated temperature, while enacting a high energy barrier of 1.68 eV to prevent isolated Ni atoms from clustering. A viable experimental route for the synthesis of Ni 1 /β 12 -BM SAC is demonstrated from computer simulation. The desired nanosheet supported single-atom bifunctional catalysts not only show great potential for achieving overall water splitting but also offer cost-effective opportunities for advancing clean energy technology.

  9. Distinct Expression Profiles and Novel Targets of MicroRNAs in Human Spermatogonia, Pachytene Spermatocytes, and Round Spermatids between OA Patients and NOA Patients

    Directory of Open Access Journals (Sweden)

    Chencheng Yao

    2017-12-01

    Full Text Available Human spermatogenesis includes three main stages, namely, the mitosis of spermatogonia, meiosis of spermatocytes, and spermiogenesis of spermatids, which are precisely regulated by epigenetic and genetic factors. Abnormality of epigenetic and genetic factors can result in aberrant spermatogenesis and eventual male infertility. However, epigenetic regulators in controlling each stage of normal and abnormal human spermatogenesis remain unknown. Here, we have revealed for the first time the distinct microRNA profiles in human spermatogonia, pachytene spermatocytes, and round spermatids between obstructive azoospermia (OA patients and non-obstructive azoospermia (NOA patients. Human spermatogonia, pachytene spermatocytes, and round spermatids from OA patients and NOA patients were isolated using STA-PUT velocity sedimentation and identified by numerous hallmarks for these cells. RNA deep sequencing showed that 396 microRNAs were differentially expressed in human spermatogonia between OA patients and NOA patients and 395 differentially expressed microRNAs were found in human pachytene spermatocytes between OA patients and NOA patients. Moreover, 378 microRNAs were differentially expressed in human round spermatids between OA patients and NOA patients. The differential expression of numerous microRNAs identified by RNA deep sequencing was verified by real-time PCR. Moreover, a number of novel targeting genes for microRNAs were predicted using various kinds of software and further verified by real-time PCR. This study thus sheds novel insights into epigenetic regulation of human normal spermatogenesis and the etiology of azoospermia, and it could offer new targets for molecular therapy to treat male infertility.

  10. Well-defined single-site monohydride silica-supported zirconium from azazirconacyclopropane

    KAUST Repository

    Hamzaoui, Bilel

    2015-01-13

    The silica-supported azazirconacyclopropane ≡SiOZr(HNMe2)(η2-NMeCH2)(NMe2) (1) leads exclusively under hydrogenolysis conditions (H2, 150°C) to the single-site monopodal monohydride silica-supported zirconium species ≡SiOZr(HNMe2)(NMe2)2H (2). Reactivity studies by contacting compound 2 with ethylene, hydrogen/ethylene, propene, or hydrogen/propene, at a temperature of 200°C revealed alkene hydrogenation.

  11. Hybrid Tunable Wideband Single Feed Antenna Element for Smartphones supporting Carrier Aggregation

    DEFF Research Database (Denmark)

    Stanev, Simon Peter; Tatomirescu, Alexandru

    2016-01-01

    This paper presents a single feed antenna with a dual branch matching circuit combined with a 3dB microstrip power divider to support the carrier aggregation in LTE advanced mobile handsets. By the use of the matching circuits, an independent and versatile broadband antenna is achieved. Hence, th...

  12. Ligand-tailored single-site silica supported titanium catalysts: Synthesis, characterization and towards cyanosilylation reaction

    International Nuclear Information System (INIS)

    Xu, Wei; Li, Yani; Yu, Bo; Yang, Jindou; Zhang, Ying; Chen, Xi; Zhang, Guofang; Gao, Ziwei

    2015-01-01

    A successive anchoring of Ti(NMe 2 ) 4 , cyclopentadiene and a O-donor ligand, 1-hydroxyethylbenzene (PEA), 1,1′-bi-2-naphthol (Binol) or 2,3-dihydroxybutanedioic acid diethyl ester (Tartrate), on silica was conducted by SOMC strategy in moderate conditions. The silica, monitored by in-situ Fourier transform infrared spectroscopy (in-situ FT-IR), was pretreated at different temperatures (200, 500 and 800 °C). The ligand tailored silica-supported titanium complexes were characterized by in-situ FT-IR, 13 C CP MAS-NMR, X-ray photoelectron spectroscopy (XPS), X-ray absorption near edge structure (XANES) and elemental analysis in detail, verifying that the surface titanium species are single sited. The catalytic activity of the ligand tailored single-site silica supported titanium complexes was evaluated by a cyanosilylation of benzaldehyde. The results showed that the catalytic activity is dependent strongly on the dehydroxylation temperatures of silica and the configuration of the ligands. - Graphical abstract: The ligand-tailored silica supportedsingle site” titanium complexes were synthesized by SOMC strategy and fully characterized. Their catalytic activity were evaluated by benzaldehyde silylcyanation. - Highlights: • Single-site silica supported Ti active species was prepared by SOMC technique. • O-donor ligand tailored Ti surface species was synthesized. • The surface species was characterized by XPS, 13 C CP-MAS NMR, XANES etc. • Catalytic activity of the Ti active species in silylcyanation reaction was evaluated

  13. Ventilation system consequence calculations to support salt well pumping single-shell tank 241-A-101

    Energy Technology Data Exchange (ETDEWEB)

    Ryan, G.W.

    1997-05-07

    This document presents the radiological dose and toxicological exposure calculations for an accident scenario involved with the ventilation system used to support salt well pumping single-shell tank 241-A-101. This tank has been listed on the Hydrogen Watch List.

  14. Ventilation system consequence calculations to support salt well pumping single-shell tank 241-A-101

    International Nuclear Information System (INIS)

    Ryan, G.W.

    1997-01-01

    This document presents the radiological dose and toxicological exposure calculations for an accident scenario involved with the ventilation system used to support salt well pumping single-shell tank 241-A-101. This tank has been listed on the Hydrogen Watch List

  15. Patients' expectations of and satisfaction with implant-supported fixed partial dentures and single crowns.

    Science.gov (United States)

    de Lima, Elis Andrade; dos Santos, Mateus Bertolini Fernandes; Marchini, Leonardo

    2012-01-01

    Patient variables and expectations may influence patients' evaluations of treatment outcomes, which are essential to the success of therapy. The main objective of this study was to compare patients' expectations before and satisfaction after receiving implant-supported fixed partial dentures (FPDs) and single crowns. A secondary objective was to evaluate other variables that may affect patient satisfaction. The sample comprised 52 volunteers (mean age: 51.2 ± 10.6 years) who had received implant-supported FPDs (n = 25) and single crowns (n = 27). A visual analog scale (VAS) was used to assess their expectations before and satisfaction after therapy with regard to mastication, esthetics, comfort, and phonetics. Patients also completed a questionnaire concerning other variables involved in the treatment and their evaluation of their clinician's conduct. Patient expectations before treatment were higher than satisfaction after treatment, but this difference was significant only for esthetics in patients who had received implant-supported FPDs. Negative correlations were found between satisfaction and age and between number of absent teeth and number of post delivery adjustments, but only for implant-supported FPDs. A positive relationship was found for the majority of questions concerning patients' evaluations of clinician conduct and VAS scores. Patients' evaluation of clinician conduct appears to be an important factor that influences their expectations before and satisfaction after receiving implant-supported FPDs and single crowns.

  16. Tunable reactivity of supported single metal atoms by impurity engineering of the MgO(001) support.

    Science.gov (United States)

    Pašti, Igor A; Johansson, Börje; Skorodumova, Natalia V

    2018-02-28

    Development of novel materials may often require a rational use of high price components, like noble metals, in combination with the possibility to tune their properties in a desirable way. Here we present a theoretical DFT study of Au and Pd single atoms supported by doped MgO(001). By introducing B, C and N impurities into the MgO(001) surface, the interaction between the surface and the supported metal adatoms can be adjusted. Impurity atoms act as strong binding sites for Au and Pd adatoms and can help to produce highly dispersed metal particles. The reactivity of metal atoms supported by doped MgO(001), as probed by CO, is altered compared to their counterparts on pristine MgO(001). We find that Pd atoms on doped MgO(001) are less reactive than on perfect MgO(001). In contrast, Au adatoms bind CO much more strongly when placed on doped MgO(001). In the case of Au on N-doped MgO(001) we find that charge redistribution between the metal atom and impurity takes place even when not in direct contact, which enhances the interaction of Au with CO. The presented results suggest possible ways for optimizing the reactivity of oxide supported metal catalysts through impurity engineering.

  17. Clinical outcomes of zirconia-based implant- and tooth-supported single crowns.

    Science.gov (United States)

    Nejatidanesh, Farahnaz; Moradpoor, Hedayat; Savabi, Omid

    2016-01-01

    Zirconia-based restorations have been increasingly used on implant and teeth abutments, but the evidence about clinical outcomes of these restorations is limited. The aim of this study was to assess up to 7-year clinical outcomes of implant- and tooth-supported zirconia-based single crowns. In this retrospective study, 261 patients with 556 single crowns supported by either teeth (324) or implants (232) were examined during 3- to 7-year follow-up (mean observation of 60.70 months for tooth and 59.20 months for implant-supported crowns). California Dental Association (CDA) quality evaluation system was used to evaluate the restorations. Soft tissue status was assessed using plaque and gingival index scores, bleeding on probing, and pocket depth. Patient and professional satisfaction were evaluated by visual analog scale (VAS). The 5-year Kaplan-Meier survival probability was 98.3 and 97.3 for implant- and tooth-supported crowns, respectively. In regard to CDA rating, most of the crowns were ranked as either excellent or acceptable (99.5 %). The recorded failures were replacement of the crown due to porcelain chipping (3), implant failure (1), and teeth extraction (5). Soft tissue parameters were not affected by the restorations compare to control teeth. The VAS was high for both patients and clinicians. Zirconia-based single crowns on both tooth and implant abutments showed promising clinical performance in this up to 7-year follow-up. The zirconia-based single crowns can be used clinically for tooth- and implant-supported restorations.

  18. On the structure and dynamics of water associated with single-supported zwitterionic and anionic membranes

    DEFF Research Database (Denmark)

    Miskowiec, A.; Buck, Z. N.; Hansen, Flemming Yssing

    2017-01-01

    We have used high-resolution quasielastic neutron scattering (QENS) to investigate the dynamics of water molecules (time scale of motion similar to ∼10-11- 10-9 s) in proximity to single-supported bilayers of the zwitterionic lipid DMPC (1,2-dimyristoyl-sn-glycero-3-phosphorylcholine......) and the anionic lipid DMPG (1,2-dimyristoyl-sn-glycero-3-phosphoglycerol) in the temperature range 160-295 K. For both membranes, the temperature dependence of the intensity of neutrons scattered elastically and incoherently from these samples indicates a series of freezing/melting transitions...... present at temperatures below the freezing point of bulk-like water. We then go on to determine the temperature dependence of the translational diffusion coefficient of the water associated with single-supported DMPG membranes containing two different amounts of water as we have previously done for DMPC...

  19. The autogenous immediate implant supported single-tooth restoration: a 5-year follow-up.

    Science.gov (United States)

    Castelnuovo, Jacopo; Sönmez, Ayse Burçin

    2012-01-01

    When replacing a missing tooth in the esthetic zone, the implant supported single tooth restoration can result in a very natural and pleasing solution for the patient, being also a conservative procedure that preserves the adjacent remaining dentition. Immediate implant placement with an immediate provisional crown can avoid stressful and uncomfortable healing time for the patient who no longer has to wear an interim removable appliance. In selected clinical situations, excellent tooth esthetics for implant supported single tooth restorations can be achieved by using the natural extracted tooth as both provisional and final restoration. No longterm data is available today as far as the survival rate of such restorations and the predictability of such a treatment modality. This case report describes a technique for utilizing the patient's extracted tooth for the fabrication of an inconspicuous final anterior restoration, reporting a 5-year follow-up.

  20. CO oxidation studies over supported noble metal catalysts and single crystals: A review

    Science.gov (United States)

    Boecker, Dirk; Gonzalez, Richard D.

    1987-01-01

    The catalytic oxidation of CO over noble metal catalysts is reviewed. Results obtained on supported noble metal catalysts and single crystals both at high pressures and under UHV conditions are compared. The underlying causes which result in surface instabilities and multiple steady-state oscillations are considered, in particular, the occurrence of hot spots. CO islands of reactivity, surface oxide formation and phase transformations under oscillatory conditions are discussed.

  1. Ligand-tailored single-site silica supported titanium catalysts: Synthesis, characterization and towards cyanosilylation reaction

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Wei; Li, Yani; Yu, Bo; Yang, Jindou; Zhang, Ying; Chen, Xi; Zhang, Guofang, E-mail: gfzhang@snnu.edu.cn; Gao, Ziwei, E-mail: zwgao@snnu.edu.cn

    2015-01-15

    A successive anchoring of Ti(NMe{sub 2}){sub 4}, cyclopentadiene and a O-donor ligand, 1-hydroxyethylbenzene (PEA), 1,1′-bi-2-naphthol (Binol) or 2,3-dihydroxybutanedioic acid diethyl ester (Tartrate), on silica was conducted by SOMC strategy in moderate conditions. The silica, monitored by in-situ Fourier transform infrared spectroscopy (in-situ FT-IR), was pretreated at different temperatures (200, 500 and 800 °C). The ligand tailored silica-supported titanium complexes were characterized by in-situ FT-IR, {sup 13}C CP MAS-NMR, X-ray photoelectron spectroscopy (XPS), X-ray absorption near edge structure (XANES) and elemental analysis in detail, verifying that the surface titanium species are single sited. The catalytic activity of the ligand tailored single-site silica supported titanium complexes was evaluated by a cyanosilylation of benzaldehyde. The results showed that the catalytic activity is dependent strongly on the dehydroxylation temperatures of silica and the configuration of the ligands. - Graphical abstract: The ligand-tailored silica supportedsingle site” titanium complexes were synthesized by SOMC strategy and fully characterized. Their catalytic activity were evaluated by benzaldehyde silylcyanation. - Highlights: • Single-site silica supported Ti active species was prepared by SOMC technique. • O-donor ligand tailored Ti surface species was synthesized. • The surface species was characterized by XPS, {sup 13}C CP-MAS NMR, XANES etc. • Catalytic activity of the Ti active species in silylcyanation reaction was evaluated.

  2. Implant-supported single crowns predictably survive to five years with limited complications.

    Science.gov (United States)

    Salinas, Thomas; Eckert, Steven

    2012-09-01

    An electronic MEDLINE search was conducted to identify cohort studies, prospective or retrospective, describing clinical performance of implant-supported single crowns. Manual searches of bibliographies from full-text articles and related reviews were conducted using numerous scientific journals. Studies were included if the mean follow-up time was at least 5 years, if articles were published in the English or German language, if patients were physically examined, and if study details were sufficient for data extraction. Of the initial 3601 studies identified, only 26 were selected. No randomized control trials were identified. The 5-year survival and complications of implant-supported single crowns. The primary outcome measure in this study was survival of endosseous implants when used to support single crowns. In addition, the clinical performance of soft tissue (peri-implantitis) and hard tissue (bone level) was documented. Clinical complications of a biomechanical nature were recorded relative to fracture of restorative materials. Poisson's regression models were used to estimate failure and complication rates at 5 years. A systematic review of the scientific literature identified 26 studies from which data were extracted (1558 placed implants). Meta-analysis identified survival of implants used to support and retain single crowns at 96.8% (95% confidence interval [CI]: 95.9%-97.6% after 5 years). The survival rate of the single crown restorations documented in 13 studies was 94.5% (95% 92.5%-95.9%) with a significantly higher survival rate when metal ceramic crowns were used in comparison with all ceramic crowns (95.4% 93.6%-96.7%; 91.2% CI: 86.8%-94.2%). Soft tissue complications, including peri-implantitis, were observed in 9.7% of the single crowns, whereas bone loss exceeding 2 mm was identified on 6.3% of the implants over the 5-year study. Prosthetic or abutment screw loosening was observed in 12.7% of the restoration and screw fracture occurred in 0

  3. Wrinkling instabilities in compressed networks of polymer supported single-wall carbon nanotubes

    Science.gov (United States)

    Harris, John; Iyer, Swathi; Huh, Ji Yeon; Fagan, Jeffrey A.; Chun, Jun Young; Hudson, Steven D.; Obrzut, Jan; Stafford, Christopher M.; Hobbie, Erik K.

    2011-03-01

    Strain-induced structural and electronic changes in polymer supported membranes of purified single-wall carbon nanotubes (SWCNTs) are evaluated through the wrinkling instabilities that develop under both uniaxial and isotropic compression. Nanotubes that have been purified by length or electronic type using density-gradient ultracentrifugation are assembled as surfactant-free thin membranes on prestrained polydimethylsiloxane (PDMS) substrates, and the strain response is measured using a broad range of techniques. The small-strain behavior is inferred from kinetic changes in the wrinkling topography of the SWCNT membranes during the slow drying of pre-swelled polymer supports. The measurements suggest a remarkable degree of strain softening that strongly couples to the anisotropic sheet resistance of the films, which we in turn relate to the microscale anisotropy that develops through excluded volume interactions. Supported by the NSF through CMMI-0969155 and the DOE through DE-FG36-08GO88160.

  4. Electrochemical reduction of CO2on graphene supported transition metals - towards single atom catalysts.

    Science.gov (United States)

    He, Haiying; Jagvaral, Yesukhei

    2017-05-10

    In this study, we have investigated the use of single metal atoms supported on defective graphene as catalysts for the electrochemical reduction of CO 2 using the first-principles approach and the computational hydrogen electrode model. Reaction pathways to produce a variety of C 1 products CO, HCOOH, HCHO, CH 3 OH and CH 4 have been studied in detail for five representative transition metals Ag, Cu, Pd, Pt, and Co. Different pathways were revealed in contrast to those found for metallic crystalline surfaces and nanoparticles. These single atom catalysts have demonstrated a general improvement in rate limiting potentials to generate C 1 hydrocarbons. They also show distinct differences in terms of their efficiency and selectivity in CO 2 reduction, which can be correlated with their elemental properties as a function of their group number in the periodic table. Six best candidates for CH 4 production are identified by conducting computational screening of 28 d-block transition metals. Ag has the lowest overpotential (0.73 V), and is followed by Zn, Ni, Pd, Pt and Ru with overpotentials all below 1 V. Cu in the supported single atom form shows a strong preference towards producing CH 3 OH with an overpotential of 0.68 V well below the value of 1.04 V for producing CH 4 .

  5. A 1-year randomised controlled trial comparing zirconia versus metal-ceramic implant supported single-tooth restorations

    DEFF Research Database (Denmark)

    Hosseini, Mandana; Worsaae, Nils; Schiodt, Morten

    2011-01-01

    To compare the biological, technical and aesthetic outcomes of single implant-supported all-ceramic versus metal-ceramic crowns.......To compare the biological, technical and aesthetic outcomes of single implant-supported all-ceramic versus metal-ceramic crowns....

  6. Study of water diffusion on single-supported bilayer lipid membranes by quasielastic neutron scattering

    DEFF Research Database (Denmark)

    Bai, M.; Miskowiec, A.; Hansen, F. Y.

    2012-01-01

    High-energy-resolution quasielastic neutron scattering has been used to elucidate the diffusion of water molecules in proximity to single bilayer lipid membranes supported on a silicon substrate. By varying sample temperature, level of hydration, and deuteration, we identify three different types...... of diffusive water motion: bulk-like, confined, and bound. The motion of bulk-like and confined water molecules is fast compared to those bound to the lipid head groups (7-10 H2O molecules per lipid), which move on the same nanosecond time scale as H atoms within the lipid molecules. Copyright (C) EPLA, 2012...

  7. Surface tailored single walled carbon nanotubes as catalyst support for direct methanol fuel cell

    Science.gov (United States)

    Kireeti, Kota V. M. K.; Jha, Neetu

    2017-10-01

    A strategy for tuning the surface property of Single Walled Carbon Nanotubes (SWNTs) for enhanced methanol oxidation reaction (MOR) and oxygen reduction reaction (ORR) along with methanol tolerance is presented. The surface functionality is tailored using controlled acid and base treatment. Acid treatment leads to the attachment of carboxylic carbon (CC) fragments to SWNT making it hydrophilic (P3-SWNT). Base treatment of P3-SWNT with 0.05 M NaOH reduces the CCs and makes it hydrophobic (P33-SWNT). Pt catalyst supported on the P3-SWNT possesses enhanced MOR whereas that supported on P33-SWNT not only enhances ORR kinetics but also possess good tolerance towards methanol oxidation as verified by the electrochemical technique.

  8. Ligand-tailored single-site silica supported titanium catalysts: Synthesis, characterization and towards cyanosilylation reaction

    Science.gov (United States)

    Xu, Wei; Li, Yani; Yu, Bo; Yang, Jindou; Zhang, Ying; Chen, Xi; Zhang, Guofang; Gao, Ziwei

    2015-01-01

    A successive anchoring of Ti(NMe2)4, cyclopentadiene and a O-donor ligand, 1-hydroxyethylbenzene (PEA), 1,1‧-bi-2-naphthol (Binol) or 2,3-dihydroxybutanedioic acid diethyl ester (Tartrate), on silica was conducted by SOMC strategy in moderate conditions. The silica, monitored by in-situ Fourier transform infrared spectroscopy (in-situ FT-IR), was pretreated at different temperatures (200, 500 and 800 °C). The ligand tailored silica-supported titanium complexes were characterized by in-situ FT-IR, 13C CP MAS-NMR, X-ray photoelectron spectroscopy (XPS), X-ray absorption near edge structure (XANES) and elemental analysis in detail, verifying that the surface titanium species are single sited. The catalytic activity of the ligand tailored single-site silica supported titanium complexes was evaluated by a cyanosilylation of benzaldehyde. The results showed that the catalytic activity is dependent strongly on the dehydroxylation temperatures of silica and the configuration of the ligands.

  9. Performance of Single Electrode-Supported Cells Operating in the Electrolysis Mode

    Energy Technology Data Exchange (ETDEWEB)

    J. E. O' Brien; G. K. Housley; D. G. Milobar

    2009-11-01

    An experimental study is under way to assess the performance of electrode-supported solid-oxide cells operating in the steam electrolysis mode for hydrogen production over a temperature range of 800 to 900ºC. Results presented in this paper were obtained from single cells, with an active area of 16 cm2 per cell. The electrolysis cells are electrode-supported, with yttria-stabilized zirconia (YSZ) electrolytes (~10 µm thick), nickel-YSZ steam/hydrogen electrodes (~1400 µm thick), and manganite (LSM) air-side electrodes. The experiments were performed over a range of steam inlet mole fractions (0.1 – 0.6), gas flow rates, and current densities (0 to 0.6 A/cm2). Steam consumption rates associated with electrolysis were measured directly using inlet and outlet dewpoint instrumentation. On a molar basis, the steam consumption rate is equal to the hydrogen production rate. Cell performance was evaluated by performing DC potential sweeps at 800, 850, and 900°C. The voltage-current characteristics are presented, along with values of area-specific resistance as a function of current density. Long-term cell performance is also assessed to evaluate cell degradation. Details of the custom single-cell test apparatus developed for these experiments are also presented.

  10. Sintering-resistant Single-Site Nickel Catalyst Supported by Metal-Organic Framework

    Energy Technology Data Exchange (ETDEWEB)

    Li, Zhanyong; Schweitzer, Neil; League, Aaron; Bernales Candia, Sandra Varinia; Peters, Aaron; Getsoian, Andrew G.; Wang, Timothy; Miller, Jeffrey T.; Vjunov, Aleksei; Fulton, John L.; Lercher, Johannes A.; Cramer, Christopher J.; Gagliardi, Laura; Hupp, Joseph; Farha, Omar

    2016-02-17

    Developing supported single-site catalysts is an important goal in heterogeneous catalysis, since the well-defined active sites afford opportunities for detailed mechanistic studies, thereby facilitating the design of improved catalysts. We present herein a method for installing Ni ions uniformly and precisely on the node of a Zr-based MOF, NU-1000, in high density and large quantity (denoted as Ni-AIM) using atomic layer deposition (ALD) in a metal–organic framework (MOF) (AIM). Ni-AIM is demonstrated to be an efficient gas-phase hydrogenation catalyst upon activation. The structure of the active sites in Ni-AIM is proposed, revealing its single-site nature. More importantly, due to the organic linker used to construct the MOF support, the Ni ions stay isolated throughout the hydrogenation catalysis, in accord with its long-term stability. A quantum chemical characterization of the catalyst and the catalytic process complements the experimental results. With validation of computational modeling protocols, we further targeted ethylene oligomerization catalysis by Ni-AIM guided by theoretical prediction. Given the generality of the AIM methodology, this emerging class of materials should prove ripe for the discovery of new catalysts for the transformation of volatile substrates.

  11. Sintering-Resistant Single-Site Nickel Catalyst Supported by Metal-Organic Framework.

    Science.gov (United States)

    Li, Zhanyong; Schweitzer, Neil M; League, Aaron B; Bernales, Varinia; Peters, Aaron W; Getsoian, Andrew Bean; Wang, Timothy C; Miller, Jeffrey T; Vjunov, Aleksei; Fulton, John L; Lercher, Johannes A; Cramer, Christopher J; Gagliardi, Laura; Hupp, Joseph T; Farha, Omar K

    2016-02-17

    Developing supported single-site catalysts is an important goal in heterogeneous catalysis since the well-defined active sites afford opportunities for detailed mechanistic studies, thereby facilitating the design of improved catalysts. We present herein a method for installing Ni ions uniformly and precisely on the node of a Zr-based metal-organic framework (MOF), NU-1000, in high density and large quantity (denoted as Ni-AIM) using atomic layer deposition (ALD) in a MOF (AIM). Ni-AIM is demonstrated to be an efficient gas-phase hydrogenation catalyst upon activation. The structure of the active sites in Ni-AIM is proposed, revealing its single-site nature. More importantly, due to the organic linker used to construct the MOF support, the Ni ions stay isolated throughout the hydrogenation catalysis, in accord with its long-term stability. A quantum chemical characterization of the catalyst and the catalytic process complements the experimental results. With validation of computational modeling protocols, we further targeted ethylene oligomerization catalysis by Ni-AIM guided by theoretical prediction. Given the generality of the AIM methodology, this emerging class of materials should prove ripe for the discovery of new catalysts for the transformation of volatile substrates.

  12. Reactivation of Reward-Related Patterns from Single Past Episodes Supports Memory-Based Decision Making.

    Science.gov (United States)

    Wimmer, G Elliott; Büchel, Christian

    2016-03-09

    Rewarding experiences exert a strong influence on later decision making. While decades of neuroscience research have shown how reinforcement gradually shapes preferences, decisions are often influenced by single past experiences. Surprisingly, relatively little is known about the influence of single learning episodes. Although recent work has proposed a role for episodes in decision making, it is largely unknown whether and how episodic experiences contribute to value-based decision making and how the values of single episodes are represented in the brain. In multiple behavioral experiments and an fMRI experiment, we tested whether and how rewarding episodes could support later decision making. Participants experienced episodes of high reward or low reward in conjunction with incidental, trial-unique neutral pictures. In a surprise test phase, we found that participants could indeed remember the associated level of reward, as evidenced by accurate source memory for value and preferences to re-engage with rewarded objects. Further, in a separate experiment, we found that high-reward objects shown as primes before a gambling task increased financial risk taking. Neurally, re-exposure to objects in the test phase led to significant reactivation of reward-related patterns. Importantly, individual variability in the strength of reactivation predicted value memory performance. Our results provide a novel demonstration that affect-related neural patterns are reactivated during later experience. Reactivation of value information represents a mechanism by which memory can guide decision making. Copyright © 2016 the authors 0270-6474/16/362868-13$15.00/0.

  13. Effect of interlayer on structure and performance of anode-supported SOFC single cells

    International Nuclear Information System (INIS)

    Eom, Tae Wook; Yang, Hae Kwang; Kim, Kyung Hwan; Yoon, Hyon Hee; Kim, Jong Sung; Park, Sang Joon

    2008-01-01

    To lower the operating temperatures in solid oxide fuel cell (SOFC) operations, anode-supported SOFC single cells with a single dip-coated interlayer were fabricated and the effect of the interlayer on the electrolyte structure and the electrical performance was investigated. For the preparation of SOFC single cells, yttria-stabilized zirconia (YSZ) electrolyte, NiO-YSZ anode, and 50% YSZ-50% strontium-doped lanthanum manganite (LSM) cathode were used. In order to characterize the cells, scanning electron microscopy (SEM) and atomic force microscopy (AFM) were utilized and the gas (air) permeability measurements were conducted for gas tightness estimation. When the interlayer was inserted onto NiO-YSZ anode, the surface roughness of anode was diminished by about 40% and dense crack-free electrolytes were obtained. The electrical performance was enhanced remarkably and the maximum power density was 0.57 W/cm 2 at 800 deg. C and 0.44 W/cm 2 at 700 deg. C. On the other hand, the effect of interlayer on the gas tightness was negligible. The characterization study revealed that the enhancement in the electrical performance was mainly attributed to the increase of ion transmission area of anode/electrolyte interface and the increase of ionic conductivity of dense crack-free electrolyte layer

  14. [Study on Sleep Staging Based on Support Vector Machines and Feature Selection in Single Channel Electroencephalogram].

    Science.gov (United States)

    Lin, Xiujing; Xia, Yongming; Qian, Songrong

    2015-06-01

    Sleep electroencephalogram (EEG) is an important index in diagnosing sleep disorders and related diseases. Manual sleep staging is time-consuming and often influenced by subjective factors. Existing automatic sleep staging methods have high complexity and a low accuracy rate. A sleep staging method based on support vector machines (SVM) and feature selection using single channel EEG single is proposed in this paper. Thirty-eight features were extracted from the single channel EEG signal. Then based on the feature selection method F-Score's definition, it was extended to multiclass with an added eliminate factor in order to find proper features, which were used as SVM classifier inputs. The eliminate factor was adopted to reduce the negative interaction of features to the result. Research on the F-Score with an added eliminate factor was further accomplished with the data from a standard open source database and the results were compared with none feature selection and standard F-Score feature selection. The results showed that the present method could effectively improve the sleep staging accuracy and reduce the computation time.

  15. SVMQA: support-vector-machine-based protein single-model quality assessment.

    Science.gov (United States)

    Manavalan, Balachandran; Lee, Jooyoung

    2017-08-15

    The accurate ranking of predicted structural models and selecting the best model from a given candidate pool remain as open problems in the field of structural bioinformatics. The quality assessment (QA) methods used to address these problems can be grouped into two categories: consensus methods and single-model methods. Consensus methods in general perform better and attain higher correlation between predicted and true quality measures. However, these methods frequently fail to generate proper quality scores for native-like structures which are distinct from the rest of the pool. Conversely, single-model methods do not suffer from this drawback and are better suited for real-life applications where many models from various sources may not be readily available. In this study, we developed a support-vector-machine-based single-model global quality assessment (SVMQA) method. For a given protein model, the SVMQA method predicts TM-score and GDT_TS score based on a feature vector containing statistical potential energy terms and consistency-based terms between the actual structural features (extracted from the three-dimensional coordinates) and predicted values (from primary sequence). We trained SVMQA using CASP8, CASP9 and CASP10 targets and determined the machine parameters by 10-fold cross-validation. We evaluated the performance of our SVMQA method on various benchmarking datasets. Results show that SVMQA outperformed the existing best single-model QA methods both in ranking provided protein models and in selecting the best model from the pool. According to the CASP12 assessment, SVMQA was the best method in selecting good-quality models from decoys in terms of GDTloss. SVMQA method can be freely downloaded from http://lee.kias.re.kr/SVMQA/SVMQA_eval.tar.gz. jlee@kias.re.kr. Supplementary data are available at Bioinformatics online. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  16. Decision Support System to Choose Digital Single Lens Camera with Simple Additive Weighting Method

    Directory of Open Access Journals (Sweden)

    Tri Pina Putri

    2016-11-01

    Full Text Available One of the technologies that evolve today is Digital Single Lens Reflex (DSLR camera. The number of products makes users have difficulties to choose the appropriate camera based on their criteria. Users may utilize several ways to help them choosing the intended camera such as using magazine, internet, and other media. This paper discusses about a web based decision support system to choose cameras by using SAW (Simple Additive Weighting method in order to make the decision process more effective and efficient. This system is expected to give recommendations about the camera which is appropriate with the user’s need and criteria based on the cost, the resolution, the feature, the ISO, and the censor. The system was implemented by using PHP and MySQL. Based on the result of questionnaire distributed to 20 respondents, 60% respondents agree that this decision support system can help users to choose the appropriate camera DSLR in accordance with the user’s need, 60% of respondents agree that this decision support system is more effective to choose DSLR camera and 75% of respondents agree that this system is more efficient. In addition, 60.55% of respondents agree that this system has met 5 Es Usability Framework.

  17. Implant-supported single-tooth restorations: a 5-year prospective study.

    Science.gov (United States)

    Wennström, Jan L; Ekestubbe, Annika; Gröndahl, Kerstin; Karlsson, Stig; Lindhe, Jan

    2005-06-01

    Comparatively few studies are available reporting at least 5 years of follow-up data of implant-supported single-tooth replacements. To evaluate prospectively the 5-year outcome of implant-supported single-tooth prosthetic restorations. Forty subjects (mean age 41 years), 23 males and 17 females, who required single-tooth prosthetic replacement for a missing tooth were recruited. A total of 45 self-tapping implants (Astra Tech ST-implants)--40 in the maxilla and five in the mandible--were installed in a two-stage procedure. Abutment connection was performed 3-6 months after implant installation. Clinical and radiographic examinations were performed at the completion of the prosthetic treatment and once a year during a 5-year follow-up period. The analysis of peri-implant bone level alteration was performed on subject and implant levels and by the use of analysis of variance and binary logistic regression. Three patients were lost during the 5 years of follow-up. One implant was lost after 2.5 years in function and another four implants could not be accounted for at the 5-year follow-up examination. The overall failure rate at 5 years was 2.6% (subject level) and 2.3% (implant level). The mean loss of marginal bone at the implants during the first year in function was 0.06 mm (SD 0.67) on the subject level and 0.02 mm (0.65) on the implant level. During the subsequent 4 years the annual change in peri-implant bone level amounted to -0.02 mm (0.22) on both subject and implant levels. Thus, the mean total bone level change over the 5-year interval was -0.14 mm (1.04) on subject level and -0.11 mm (1.00) on the implant level of analysis (p>0.05). The frequency of implants with a 5-year bone loss of > or =1 mm was 13%. Approximately 50% of the implants demonstrated no bone loss. The present clinical trial on single-tooth replacements with the Astra Tech implant system demonstrated that the bone loss during the first year of function as well as annually thereafter was

  18. Electronic structure of surface-supported bis(phthalocyaninato) terbium(III) single molecular magnets.

    Science.gov (United States)

    Vitali, Lucia; Fabris, Stefano; Conte, Adriano Mosca; Brink, Susan; Ruben, Mario; Baroni, Stefano; Kern, Klaus

    2008-10-01

    The electronic structure of isolated bis(phthalocyaninato) terbium(III) molecules, a novel single-molecular-magnet (SMM), supported on the Cu(111) surface has been characterized by density functional theory and scanning tunneling spectroscopy. These studies reveal that the interaction with the metal surface preserves both the molecular structure and the large spin magnetic moment of the metal center. The 4f electron states are not perturbed by the adsorption while a strong molecular/metal interaction can induce the suppression of the minor spin contribution delocalized over the molecular ligands. The calculations show that the inherent spin magnetic moment of the molecule is only weakly affected by the interaction with the surface and suggest that the SMM character might be preserved.

  19. Single Image Super-Resolution by Non-Linear Sparse Representation and Support Vector Regression

    Directory of Open Access Journals (Sweden)

    Yungang Zhang

    2017-02-01

    Full Text Available Sparse representations are widely used tools in image super-resolution (SR tasks. In the sparsity-based SR methods, linear sparse representations are often used for image description. However, the non-linear data distributions in images might not be well represented by linear sparse models. Moreover, many sparsity-based SR methods require the image patch self-similarity assumption; however, the assumption may not always hold. In this paper, we propose a novel method for single image super-resolution (SISR. Unlike most prior sparsity-based SR methods, the proposed method uses non-linear sparse representation to enhance the description of the non-linear information in images, and the proposed framework does not need to assume the self-similarity of image patches. Based on the minimum reconstruction errors, support vector regression (SVR is applied for predicting the SR image. The proposed method was evaluated on various benchmark images, and promising results were obtained.

  20. Automatic pathology classification using a single feature machine learning support - vector machines

    Science.gov (United States)

    Yepes-Calderon, Fernando; Pedregosa, Fabian; Thirion, Bertrand; Wang, Yalin; Lepore, Natasha

    2014-03-01

    Magnetic Resonance Imaging (MRI) has been gaining popularity in the clinic in recent years as a safe in-vivo imaging technique. As a result, large troves of data are being gathered and stored daily that may be used as clinical training sets in hospitals. While numerous machine learning (ML) algorithms have been implemented for Alzheimer's disease classification, their outputs are usually difficult to interpret in the clinical setting. Here, we propose a simple method of rapid diagnostic classification for the clinic using Support Vector Machines (SVM)1 and easy to obtain geometrical measurements that, together with a cortical and sub-cortical brain parcellation, create a robust framework capable of automatic diagnosis with high accuracy. On a significantly large imaging dataset consisting of over 800 subjects taken from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database, classification-success indexes of up to 99.2% are reached with a single measurement.

  1. Single-site SBA-15 supported zirconium catalysts. Synthesis, characterization and toward cyanosilylation reaction

    International Nuclear Information System (INIS)

    Xu, Wei; Yu, Bo; Zhang, Ying; Chen, Xi; Zhang, Guofang; Gao, Ziwei

    2015-01-01

    Graphical abstract: Ligand-modified signal-site SBA-15 supported zirconium catalysts were synthesized by SOMC method and characterized by a variety of techniques. The zirconium surface complexes show high catalytic efficiency for cyanosilylation of benzaldehyde. - Highlights: • Some Zr active species have been anchored on the surface of SBA-15 by SOMC technique. • The structures of the Zr species have been characterized by a variety of techniques. • The anchored Zr species are single-sited surface complexes. • The Zr surface complexes are catalytic active for cyanosilylation of benzaldehyde. - Abstract: A successive anchoring of Zr(NMe 2 ) 4 , cyclopentadiene and a O-donor ligand, 1-hydroxyethylbenzene (PEA), 1,1′-bi-2-naphthol (Binol) or 2,3-dihydroxybutanedioic acid diethyl ester (Tartrate), on dehydroxylated SBA-15 pretreated at 500 °C for 16 h (SBA-15 -500 ) was conducted by SOMC strategy in moderate conditions. The dehydoxylation of SBA-15 was monitored by in situ Fourier transform infrared spectroscopy (in situ FT-IR). The ligand-modified SBA-15 -500 supported zirconium complexes were characterized by in situ FT-IR, 13 C CP MAS-NMR, X-ray photoelectron spectroscopy (XPS), inductively coupled plasma mass spectrometry (ICP-MAS) and elemental analysis in detail, verifying that the surface zirconium species are single-sited. The catalytic activity of these complexes was evaluated by cyanosilylation of benzaldehyde. The results showed that the catalytic activity is dependent strongly on the structure of surface species and the configuration of the ligands

  2. Single-site SBA-15 supported zirconium catalysts. Synthesis, characterization and toward cyanosilylation reaction

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Wei; Yu, Bo; Zhang, Ying; Chen, Xi; Zhang, Guofang, E-mail: gfzhang@snnu.edu.cn; Gao, Ziwei, E-mail: zwgao@snnu.edu.cn

    2015-01-15

    Graphical abstract: Ligand-modified signal-site SBA-15 supported zirconium catalysts were synthesized by SOMC method and characterized by a variety of techniques. The zirconium surface complexes show high catalytic efficiency for cyanosilylation of benzaldehyde. - Highlights: • Some Zr active species have been anchored on the surface of SBA-15 by SOMC technique. • The structures of the Zr species have been characterized by a variety of techniques. • The anchored Zr species are single-sited surface complexes. • The Zr surface complexes are catalytic active for cyanosilylation of benzaldehyde. - Abstract: A successive anchoring of Zr(NMe{sub 2}){sub 4}, cyclopentadiene and a O-donor ligand, 1-hydroxyethylbenzene (PEA), 1,1′-bi-2-naphthol (Binol) or 2,3-dihydroxybutanedioic acid diethyl ester (Tartrate), on dehydroxylated SBA-15 pretreated at 500 °C for 16 h (SBA-15{sub -500}) was conducted by SOMC strategy in moderate conditions. The dehydoxylation of SBA-15 was monitored by in situ Fourier transform infrared spectroscopy (in situ FT-IR). The ligand-modified SBA-15{sub -500} supported zirconium complexes were characterized by in situ FT-IR, {sup 13}C CP MAS-NMR, X-ray photoelectron spectroscopy (XPS), inductively coupled plasma mass spectrometry (ICP-MAS) and elemental analysis in detail, verifying that the surface zirconium species are single-sited. The catalytic activity of these complexes was evaluated by cyanosilylation of benzaldehyde. The results showed that the catalytic activity is dependent strongly on the structure of surface species and the configuration of the ligands.

  3. Redox cycling performance of inert-substrate-supported tubular single cells with nickel anode current collector

    Science.gov (United States)

    Zhao, Kai; Kim, Bok-Hee; Xu, Qing; Du, Yanhai; Ahn, Byung-Guk

    2015-10-01

    An inert-substrate-supported tubular single cell, with a configuration of porous yttria-stabilized zirconia (YSZ) supporter/Ni anode current collector/Ni-Ce0.8Sm0.2O1.9 anode/YSZ/Ce0.8Sm0.2O1.9 bi-layer electrolyte/La0.6Sr0.4Co0.2Fe0.8O3-δ cathode, has been fabricated by extrusion and dip-coating techniques. Thickness of the Ni layer is modified by controlling the number of dip-coatings from one to four. Electrochemical performance and redox cycling stability of the single cell are investigated with respect to the microstructure of the Ni layer. Increasing the thickness of the Ni layer enhances the maximum power density of the cell, while it is unfavorable for the redox cycling stability. Considering the trade-off between these two aspects, an optimum dip-coating time is determined to be two. The cell shows a reasonable maximum power density of 453 mW cm-2 at 800 °C, as well as good redox cycling stability within eight redox cycles. Additionally, 10 vol.% Ce0.8Sm0.2O1.9 ceramic particle is incorporated into the Ni layer to further improve the redox cycling stability. The cell exhibits enhanced redox cycling performance after the Ce0.8Sm0.2O1.9 incorporation. Within seven redox cycles, the cell voltage loss is less than 1% at a current density of 400 mA cm-2, and it maintains 93% of its initial performance after 11 redox cycles.

  4. Reactivity of a Carbon-Supported Single-Site Molybdenum Dioxo Catalyst for Biodiesel Synthesis

    Energy Technology Data Exchange (ETDEWEB)

    Mouat, Aidan R.; Lohr, Tracy L.; Wegener, Evan C.; Miller, Jeffrey T.; Delferro, Massimiliano; Stair, Peter C.; Marks, Tobin J.

    2016-08-23

    A single-site molybdenum dioxo catalyst, (Oc)2Mo(=O)2@C, was prepared via direct grafting of MoO2Cl2(dme) (dme = 1,2-dimethoxyethane) on high-surface- area activated carbon. The physicochemical and chemical properties of this catalyst were fully characterized by N2 physisorption, ICP-AES/OES, PXRD, STEM, XPS, XAS, temperature-programmed reduction with H2 (TPR-H2), and temperature-programmed NH3 desorption (TPD-NH3). The single-site nature of the Mo species is corroborated by XPS and TPR-H2 data, and it exhibits the lowest reported MoOx Tmax of reduction reported to date, suggesting a highly reactive MoVI center. (Oc)2Mo(=O)2@C catalyzes the transesterification of a variety of esters and triglycerides with ethanol, exhibiting high activity at moderate temperatures (60-90 °C) and with negligible deactivation. (Oc)2Mo(=O)2@C is resistant to water and can be recycled at least three times with no loss of activity. The transesterification reaction is determined experimentally to be first order in [ethanol] and first order in [Mo] with ΔH = 10.5(8) kcal mol-1 and ΔS = -32(2) eu. The low energy of activation is consistent with the moderate conditions needed to achieve rapid turnover. This highly active carbon-supported single-site molybdenum dioxo species is thus an efficient, robust, and lowcost catalyst with significant potential for transesterification processes.

  5. Implant-supported single-tooth restorations. A 12-year prospective study.

    Science.gov (United States)

    Donati, Mauro; Ekestubbe, Annika; Lindhe, Jan; Wennström, Jan L

    2016-10-01

    The aim of this study was to evaluate prospectively the 12-year outcome of implant-supported single-tooth restorations. Originally 45 self-tapping Astra Tech TiOblast ® ST-implants were installed by a two-stage protocol in 40 subjects requiring single-tooth prosthetic replacement for a missing tooth. Clinical and radiologic examinations were performed at completion of the prosthetic treatment 4-7 months after implant installation surgery and after 5 and 12 years in function. At 12 years 31 patients and 35 implants were available for evaluation. The overall failure rate after 12 years was 10.3% on the subject level and 9.1% on the implant level. The mean bone loss amounted to 0.67 mm (SD 2.20) on a subject level and 0.47 mm (1.72) on an implant level. Three subjects (10%) and three implants (8.6%) were diagnosed with peri-implantitis. Five subjects had experienced technical complications; three incidences of loosening of the abutment retention screw during the first 5 years and two minor porcelain fracture of the crown (two patients) between 5- and 12-years of follow-up. The findings reported in this 12-year prospective case series suggest that the use of the Astra Tech dental implants may be a valid treatment alternative for single-tooth replacement prostheses. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  6. 77 FR 58404 - Announcing the Award of Two Urgent Single-Source Grants To Support Unaccompanied Alien Children...

    Science.gov (United States)

    2012-09-20

    ...] Announcing the Award of Two Urgent Single-Source Grants To Support Unaccompanied Alien Children Program...) announces the award of two urgent single-source grants from the Unaccompanied Alien Children's Program to... providing services under the Unaccompanied Alien Children's program. Award Grantee organization Location...

  7. Homogeneity of Surface Sites in Supported Single-Site Metal Catalysts: Assessment with Band Widths of Metal Carbonyl Infrared Spectra.

    Science.gov (United States)

    Hoffman, Adam S; Fang, Chia-Yu; Gates, Bruce C

    2016-10-06

    Determining and controlling the uniformity of isolated metal sites on surfaces of supports are central goals in investigations of single-site catalysts because well-defined species provide opportunities for fundamental understanding of the surface sites. CO is a useful probe of surface metal sites, often reacting with them to form metal carbonyls, the infrared spectra of which provide insights into the nature of the sites and the metal-support interface. Metals bonded to various support surface sites give broad bands in the spectra, and when narrow bands are observed, they indicate a high degree of uniformity of the metal sites. Much recent work on single-site catalysts has been done with supports that are inherently nonuniform, giving supported metal species that are therefore nonuniform. Herein we summarize values of ν CO data characterizing supported iridium gem-dicarbonyls, showing that the most nearly uniform of them are those supported on zeolites and the least uniform are those supported on metal oxides. Guided by ν CO data of supported iridium gem-dicarbonyls, we have determined new, general synthesis methods to maximize the degree of uniformity of iridium species on zeolites and on MgO. We report results for a zeolite HY-supported iridium gem-dicarbonyl with full width at half-maximum values of only 4.6 and 5.2 cm -1 characterizing the symmetric and asymmetric CO stretches and implying that this is the most nearly uniform supported single-site metal catalyst.

  8. Prenatal development supports a single origin of laryngeal echolocation in bats.

    Science.gov (United States)

    Wang, Zhe; Zhu, Tengteng; Xue, Huiling; Fang, Na; Zhang, Junpeng; Zhang, Libiao; Pang, Jian; Teeling, Emma C; Zhang, Shuyi

    2017-01-09

    Bat laryngeal echolocation is considered as one of the most complex and diverse modes of auditory sensory perception in animals and its evolutionary history has been the cause of many scientific controversies in the past two decades. To date, the majority of scientific evidence supports that bats (Chiroptera) are divided into two subordinal groups: Yinpterochiroptera, containing the laryngeal echolocating superfamily Rhinolophidae as sister taxa to the non-laryngeal echolocating family Pteropodidae; and Yangochiroptera, containing all other laryngeal echolocating lineages. This topology has led to an unanswered question in mammalian biology: was laryngeal echolocation lost in the ancestral pteropodids or gained convergently in the echolocating bat lineages? To date, there is insufficient and conflicting evidence from fossil, genomic, morphological and phylogenomic data to resolve this question. We detail an ontogenetic study of fetal cochlear development from seven species of bats and five outgroup mammals and show that in early fetal development, all bats including the non-laryngeal echolocating pteropodids have a similarly large cochlea typically associated with laryngeal echolocation abilities. The subsequent cochlear growth rate in the pteropodids is the slowest of all mammals and leads to the pteropodids and the non-echolocating lineages eventually sharing a similar cochlear morphospace as adults. The results suggest that pteropodids maintain a vestigial developmental stage indicative of past echolocation capabilities and thus support a single origin of laryngeal echolocation in bats.

  9. On the structure and dynamics of water associated with single-supported zwitterionic and anionic membranes

    Science.gov (United States)

    Miskowiec, A.; Buck, Z. N.; Hansen, F. Y.; Kaiser, H.; Taub, H.; Tyagi, M.; Diallo, S. O.; Mamontov, E.; Herwig, K. W.

    2017-03-01

    We have used high-resolution quasielastic neutron scattering (QENS) to investigate the dynamics of water molecules (time scale of motion ˜10-11-10-9 s) in proximity to single-supported bilayers of the zwitterionic lipid DMPC (1,2-dimyristoyl-sn-glycero-3-phosphorylcholine) and the anionic lipid DMPG (1,2-dimyristoyl-sn-glycero-3-phosphoglycerol) in the temperature range 160-295 K. For both membranes, the temperature dependence of the intensity of neutrons scattered elastically and incoherently from these samples indicates a series of freezing/melting transitions of the membrane-associated water, which have not been observed in previous studies of multilayer membranes. We interpret these successive phase transitions as evidence of different types of water that are common to the two membranes and which are defined by their local environment: bulk-like water located furthest from the membrane and two types of confined water in closer proximity to the lipids. Specifically, we propose a water type termed "confined 2" located within and just above the lipid head groups of the membrane and confined 1 water that lies between the bulk-like and confined 2 water. Confined 1 water is only present at temperatures below the freezing point of bulk-like water. We then go on to determine the temperature dependence of the translational diffusion coefficient of the water associated with single-supported DMPG membranes containing two different amounts of water as we have previously done for DMPC. To our knowledge, there have been no previous studies comparing the dynamics of water in proximity to zwitterionic and anionic membranes. Our analysis of the water dynamics of the DMPG and DMPC membranes supports the classification of water types that we have inferred from their freezing/melting behavior. However, just as we observe large differences in the freezing/melting behavior between these model membranes for the same water type, our measurements demonstrate variation between these

  10. Mitochondrial Genome Diversity of Native Americans Supports a Single Early Entry of Founder Populations into America

    Science.gov (United States)

    Silva Jr., Wilson A.; Bonatto, Sandro L.; Holanda, Adriano J.; Ribeiro-dos-Santos, Andrea K.; Paixão, Beatriz M.; Goldman, Gustavo H.; Abe-Sandes, Kiyoko; Rodriguez-Delfin, Luis; Barbosa, Marcela; Paçó-Larson, Maria Luiza; Petzl-Erler, Maria Luiza; Valente, Valeria; Santos, Sidney E. B.; Zago, Marco A.

    2002-01-01

    There is general agreement that the Native American founder populations migrated from Asia into America through Beringia sometime during the Pleistocene, but the hypotheses concerning the ages and the number of these migrations and the size of the ancestral populations are surrounded by controversy. DNA sequence variations of several regions of the genome of Native Americans, especially in the mitochondrial DNA (mtDNA) control region, have been studied as a tool to help answer these questions. However, the small number of nucleotides studied and the nonclocklike rate of mtDNA control-region evolution impose several limitations to these results. Here we provide the sequence analysis of a continuous region of 8.8 kb of the mtDNA outside the D-loop for 40 individuals, 30 of whom are Native Americans whose mtDNA belongs to the four founder haplogroups. Haplogroups A, B, and C form monophyletic clades, but the five haplogroup D sequences have unstable positions and usually do not group together. The high degree of similarity in the nucleotide diversity and time of differentiation (i.e., ∼21,000 years before present) of these four haplogroups support a common origin for these sequences and suggest that the populations who harbor them may also have a common history. Additional evidence supports the idea that this age of differentiation coincides with the process of colonization of the New World and supports the hypothesis of a single and early entry of the ancestral Asian population into the Americas. PMID:12022039

  11. Interventions to Support Social Interaction in Children with Autism Spectrum Disorders: A Systematic Review of Single Case Studies

    Science.gov (United States)

    Ozuna, Jennifer; Mavridis, Alexis; Hott, Brittany L.

    2015-01-01

    Social interaction is a core deficit in individuals with autism spectrum disorder (ASD). Therefore, parents and teachers need effective interventions to support students with ASD. This synthesis provides a quantitative analysis of single-subject studies that examine interventions to support social interactions in children with ASD. Results suggest…

  12. Dose-response relationship for translocation induction in spermatogonia of the crab-eating monkey (Macaca fascicularis) by chronic γ-ray-irradiation

    International Nuclear Information System (INIS)

    Tobari, Izuo; Matsuda, Yoichi; Xiaohung, Gu; Yamagiwa, Junju; Utsugi, Toyoko; Kitazume, Masayuki; Okamoto, Masanori

    1988-01-01

    The induction of reciprocal translocations in spermatogonia of the crab-eating monkey (Macaca fascicularis) by chronic γ-irradiation was examined. The frequencies of translocation per cell were 0.15% at 0.3 Gy, 0.27% at 1.0 Gy and 0.33% at 1.5 Gy. The dose-response relationship for translocation yield was a linear one with a regression coefficient (b) of 0.16 · 10 -2 . When the slope (b) of the regression line was compared with that at a high dose rate (0.25 Gy/min, b = 1.79 · 10 -2 , it was clear that the induction rate of translocations after chronic γ-irradiation was only about one-tenth of that after high-dose-rate irradiation. Thus, there was evidence for a pronounced dose-rate effect in the crab-eating monkey. (author). 27 refs.; 2 figs.; 3 tabs

  13. Complete digital workflow for the production of implant-supported single-unit monolithic crowns.

    Science.gov (United States)

    Joda, Tim; Brägger, Urs

    2014-11-01

    The aim of this case series was to introduce a complete digital workflow for the production of monolithic implant crowns. Six patients were treated with implant-supported crowns made of resin nano ceramic (RNC). Starting with an intraoral optical scan (IOS), and following a CAD/CAM process, the monolithic crowns were bonded either to a novel prefabricated titanium abutment base (group A) or to a CAD/CAM-generated individualized titanium abutment (group B) in premolar or molar sites on a soft tissue level dental implant. Economic analyses included clinical and laboratory steps. An esthetic evaluation was performed to compare the two abutment-crown combinations. None of the digitally constructed RNC crowns required any clinical adaptation. Overall mean work time calculations revealed obvious differences for group A (65.3 min) compared with group B (86.5 min). Esthetic analysis demonstrated a more favorable outcome for the prefabricated bonding bases. Prefabricated or individualized abutments on monolithic RNC crowns using CAD/CAM technology in a model-free workflow seem to provide a feasible and streamlined treatment approach for single-edentulous space rehabilitation in the posterior region. However, RNC as full-contour material has to be considered experimental, and further large-scale clinical investigations with long-term follow-up observation are necessary. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  14. Single-component supported lipid bilayers probed using broadband nonlinear optics.

    Science.gov (United States)

    Olenick, Laura L; Chase, Hilary M; Fu, Li; Zhang, Yun; McGeachy, Alicia C; Dogangun, Merve; Walter, Stephanie R; Wang, Hong-Fei; Geiger, Franz M

    2018-01-31

    Broadband SFG spectroscopy is shown to offer considerable advantages over scanning systems in terms of signal-to-noise ratios when probing well-formed single-component supported lipid bilayers formed from zwitterionic lipids with PC headgroups. The SFG spectra obtained from bilayers formed from DOPC, POPC, DLPC, DMPC, DPPC and DSPC show a common peak at ∼2980 cm -1 , which is subject to interference between the C-H and the O-H stretches from the aqueous phase, while membranes having transition temperatures above the laboratory temperature produce SFG spectra with at least two additional peaks, one at ∼2920 cm -1 and another at ∼2880 cm -1 . The results validate spectroscopic and structural data from SFG experiments utilizing asymmetric bilayers in which one leaflet differs from the other in the extent of deuteration. Differences in H 2 O-D 2 O exchange experiments reveal that the lineshapes of the broadband SFG spectra are significantly influenced by interference from OH oscillators in the aqueous phase, even when those oscillators are not probed by the incident infrared light in our broadband setup. In the absence of spectral interference from the OH stretches of the solvent, the alkyl chain terminal methyl group of the bilayer is found to be tilted at an angle of 15° to 35° from the surface normal.

  15. Structure and composition of single Pt–Ru electrocatalyst nanoparticles supported on multiwall carbon nanotubes

    International Nuclear Information System (INIS)

    Paraguay-Delgado, Francisco; Malac, Marek; Alonso-Nuñez, Gabriel

    2014-01-01

    Individual Pt-Ru nanoparticles (NPs) supported on multiwall carbon nanotubes (MWCNTs) synthesized by microemulsion method were characterized by nano beam diffraction (NBD) and high resolution imaging in transmission electron microscopy (TEM). Comparing the TEM images and NBD to simulations provided insight into particle composition, structure and morphology in three dimensions. In particular, the NBD allowed us to detect various components of the individual NPs that would be difficult to observe otherwise. We find that the NPs contain four different components: Pt–RuO 2 , Pt–Ru, RuO 2 and metallic Pt. Often an individual NP is composed of more than one component. The most frequently encountered external morphology is close to a spherical shape and ∼3.7 nm in diameter. The collective properties of NPs’ assemblies were studied by thermogravimetry, differential thermal analysis and x-ray diffraction. The results allowed us to gain some insight into the relation of the NPs’ structure and composition with their catalytic performance, and revealed the presence of components not detectable by bulk methods. The electrocatalytic properties were evaluated by CO stripping, methanol oxidation and oxygen reduction. Bulk characterization methods miss many properties and structures present in the sample due to low volume fraction and due to overlap of reflections. Single NPs should be analyzed to obtain reliable indication of sample composition. (paper)

  16. Single-site SBA-15 supported zirconium catalysts. Synthesis, characterization and toward cyanosilylation reaction

    Science.gov (United States)

    Xu, Wei; Yu, Bo; Zhang, Ying; Chen, Xi; Zhang, Guofang; Gao, Ziwei

    2015-01-01

    A successive anchoring of Zr(NMe2)4, cyclopentadiene and a O-donor ligand, 1-hydroxyethylbenzene (PEA), 1,1‧-bi-2-naphthol (Binol) or 2,3-dihydroxybutanedioic acid diethyl ester (Tartrate), on dehydroxylated SBA-15 pretreated at 500 °C for 16 h (SBA-15-500) was conducted by SOMC strategy in moderate conditions. The dehydoxylation of SBA-15 was monitored by in situ Fourier transform infrared spectroscopy (in situ FT-IR). The ligand-modified SBA-15-500 supported zirconium complexes were characterized by in situ FT-IR, 13C CP MAS-NMR, X-ray photoelectron spectroscopy (XPS), inductively coupled plasma mass spectrometry (ICP-MAS) and elemental analysis in detail, verifying that the surface zirconium species are single-sited. The catalytic activity of these complexes was evaluated by cyanosilylation of benzaldehyde. The results showed that the catalytic activity is dependent strongly on the structure of surface species and the configuration of the ligands.

  17. Support for non-locking parallel reception of packets belonging to a single memory reception FIFO

    Science.gov (United States)

    Chen, Dong [Yorktown Heights, NY; Heidelberger, Philip [Yorktown Heights, NY; Salapura, Valentina [Yorktown Heights, NY; Senger, Robert M [Yorktown Heights, NY; Steinmacher-Burow, Burkhard [Boeblingen, DE; Sugawara, Yutaka [Yorktown Heights, NY

    2011-01-27

    A method and apparatus for distributed parallel messaging in a parallel computing system. A plurality of DMA engine units are configured in a multiprocessor system to operate in parallel, one DMA engine unit for transferring a current packet received at a network reception queue to a memory location in a memory FIFO (rmFIFO) region of a memory. A control unit implements logic to determine whether any prior received packet destined for that rmFIFO is still in a process of being stored in the associated memory by another DMA engine unit of the plurality, and prevent the one DMA engine unit from indicating completion of storing the current received packet in the reception memory FIFO (rmFIFO) until all prior received packets destined for that rmFIFO are completely stored by the other DMA engine units. Thus, there is provided non-locking support so that multiple packets destined for a single rmFIFO are transferred and stored in parallel to predetermined locations in a memory.

  18. Support effects on adsorption and catalytic activation of O2 in single atom iron catalysts with graphene-based substrates.

    Science.gov (United States)

    Gao, Zheng-Yang; Yang, Wei-Jie; Ding, Xun-Lei; Lv, Gang; Yan, Wei-Ping

    2018-03-07

    The adsorption and catalytic activation of O 2 on single atom iron catalysts with graphene-based substrates were investigated systematically by density functional theory calculation. It is found that the support effects of graphene-based substrates have a significant influence on the stability of the single atom catalysts, the adsorption configuration, the electron transfer mechanism, the adsorption energy and the energy barrier. The differences in the stable adsorption configuration of O 2 on single atom iron catalysts with different graphene-based substrates can be well understood by the symmetrical matching principle based on frontier molecular orbital analysis. There are two different mechanisms of electron transfer, in which the Fe atom acts as the electron donor in single vacancy graphene-based substrates while the Fe atom mainly acts as the bridge for electron transfer in double vacancy graphene-based substrates. The Fermi softness and work function are good descriptors of the adsorption energy and they can well reveal the relationship between electronic structure and adsorption energy. This single atom iron catalyst with single vacancy graphene modified by three nitrogen atoms is a promising non-noble metal single atom catalyst in the adsorption and catalytic oxidation of O 2 . Furthermore, the findings can lay the foundation for the further study of graphene-based support effects and provide a guideline for the development and design of new non-noble-metal single atom catalysts.

  19. In patients requiring single-tooth replacement, what are the outcomes of implant- as compared to tooth-supported restorations?

    Science.gov (United States)

    Salinas, Thomas J; Eckert, Steven E

    2007-01-01

    The study provides a systematic review of the literature to determine the long-term survival characteristics of single implant-supported crowns and fixed partial dentures. A search of the MEDLINE, EMBASE, and Cochrane Collaboration databases was conducted to identify articles that compared survival and success of fixed partial dentures and single implant-supported crowns. In addition to comparative cohort studies, articles that pertained specifically to single implant-supported crowns or fixed partial dentures were included in this review. Inclusion criteria for implant and fixed partial denture articles included a minimum 2-year study, primary publication in the English language, a minimum of 12 implants, implants designed to osseointegrate, and inclusion of data regarding implant and prosthetic performance. Data were analyzed using cumulative proportions of survival and success for both prosthetic types and for individual implants. Wilson score method was used to establish 95% confidence intervals for each population. The chi-square test for homogeneity was performed. The literature search failed to identify any articles that directly compared survival or success of single implant-supported restorations with fixed partial dentures. Following the search criteria, and independent analysis by reviewers, 51 articles were identified in the implant literature (agreement, 95.42%; kappa coefficient, 0.8976), and 41 were identified in the fixed partial denture literature (agreement, 90.97%; kappa coefficient, 0.7524). Pooled success of single-implant restorations at 60 months was 95.1% (CI: 92.2%-98.0%), while fixed partial dentures of all designs exhibited an 84.0% success rate (CI: 79.1%-88.9%). This systematic review of the scientific literature failed to demonstrate any direct comparative studies assessing clinical performance of single implant-supported crowns and tooth-supported fixed partial dentures. The analysis suggested differences at 60 months between survival

  20. Well-Defined Silica Supported Aluminum Hydride: Another Step Towards the Utopian Single Site Dream?

    KAUST Repository

    Werghi, Baraa

    2015-07-17

    Reaction of triisobutylaluminum with SBA15700 at room temperature occurs by two parallel pathways involving either silanol or siloxane bridges. It leads to the formation of a well-defined bipodal [(≡SiO)2Al-CH2CH(CH3)2] 1a, silicon isobutyl [≡Si-CH2CH(CH3)2] 1b and a silicon hydride [≡Si-H] 1c. Their structural identity was characterized by FT-IR and advance solid-state NMR spectroscopies (1H, 13C, 29Si, 27Al and 2D multiple quantum), elemental and gas phase analysis, and DFT calculations. The reaction involves the formation of a highly reactive monopodal intermediate: [≡SiO-Al-[CH2CH(CH3)2]2], with evolution of isobutane. This intermediate undergoes two parallel routes: Transfer of either one isobutyl fragment or of one hydride to an adjacent silicon atom. Both processes occur by opening of a strained siloxane bridge, ≡Si-O-Si≡ but with two different mechanisms, showing that the reality of “single site” catalyst may be an utopia: DFT calculations indicate that isobutyl transfer occurs via a simple metathesis between the Al-isobutyl and O-Si bonds, while hydride transfer occurs via a two steps mechanism, the first one is a ß-H elimination to Al with elimination of isobutene, whereas the second is a metathesis step between the formed Al-H bond and a O-Si bond. Thermal treatment of 1a (at 250 °C) under high vacuum (10-5 mbar) generates Al-H through a ß-H elimination of isobutyl fragment. These supported well-defined Al-H which are highly stable with time, are tetra, penta and octa coordinated as demonstrated by IR and 27Al–1H J-HMQC NMR spectroscopy. All these observations indicate that surfaces atoms around the site of grafting play a considerable role in the reactivity of a single site system.

  1. Well-defined silica supported aluminum hydride: another step towards the utopian single site dream?

    Science.gov (United States)

    Werghi, Baraa; Bendjeriou-Sedjerari, Anissa; Sofack-Kreutzer, Julien; Jedidi, Abdesslem; Abou-Hamad, Edy; Cavallo, Luigi; Basset, Jean-Marie

    2015-10-01

    processes occur by opening of a strained siloxane bridge, Si-O-Si but with two different mechanisms, showing that the reality of "single site" catalyst may be an utopia: DFT calculations indicate that isobutyl transfer occurs via a simple metathesis between the Al-isobutyl and O-Si bonds, while hydride transfer occurs via a two steps mechanism, the first one is a β-H elimination to Al with elimination of isobutene, whereas the second is a metathesis step between the formed Al-H bond and a O-Si bond. Thermal treatment of 1a (at 250 °C) under high vacuum (10 -5 mbar) generates Al-H through a β-H elimination of isobutyl fragment. These supported well-defined Al-H which are highly stable with time, are tetra, penta and octa coordinated as demonstrated by IR and 27 Al- 1 H J-HMQC NMR spectroscopy. All these observations indicate that surfaces atoms around the site of grafting play a considerable role in the reactivity of a single site system.

  2. Trade study of leakage detection, monitoring, and mitigation technologies to support Hanford single-shell waste retrieval

    International Nuclear Information System (INIS)

    Hertzel, J.S.

    1996-03-01

    The U.S. Department of Energy has established the Tank Waste Remediation System to safely manage and dispose of low-level, high-level, and transuranic wastes currently stored in underground storage tanks at the Hanford Site in Eastern Washington. This report supports the Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement) Milestone No. M-45-08-T01 and addresses additional issues regarding single-shell tank leakage detection, monitoring, and mitigation technologies and provide an indication of the scope of leakage detection, monitoring, and mitigation activities necessary to support the Tank Waste Remedial System Initial Single-shell Tank Retrieval System project

  3. Anode-supported single-chamber SOFCs based on gadolinia doped ceria electrolytes

    Directory of Open Access Journals (Sweden)

    Morales, M.

    2008-12-01

    Full Text Available The utilization of anode supported electrolytes is a useful strategy to increase the electrical properties of the solid oxide fuel cells, because it is possible to decrease considerably the thickness of the electrolytes. We have prepared successfully singlechamber fuel cells of gadolinia doped ceria electrolytes Ce1-xGdxO2-y (CGO supported on an anode formed by a cermet of Ni-CGO. Mixtures of precursor powders of NiO and gadolinium doped ceria with different particle sizes and compositions were analyzed to obtain optimal bulk porous anodes to be used as anode supported fuel cells. Doped ceria electrolytes were prepared by sol-gel related techniques. Then, ceria based electrolytes were deposited by dip coating at different thickness (15-30 µm using an ink prepared with nanometric powders of electrolytes dispersed in a commercial liquid polymer. Cathodes of La1-xSrxCoO3-s (LSCO were also prepared by sol-gel related techniques and were deposited by dip coating on the electrolyte thick films. Finally, electrical properties were determined in a single-chamber reactor where propane as fuel was mixed with synthetic air above the higher explosive limit. Stable density currents were obtained in these experimental conditions, but flow rates of the carrier gas and propane partial pressure were determinants for the optimization of the electrical properties of the fuel cells.

    La utilización de electrolitos soportados en el ánodo es una estrategia muy útil para mejorar las propiedades eléctricas de las pilas de combustible de óxido sólido, debido a que permiten disminuir considerablemente el espesor de los electrolitos. Para este trabajo, se han preparado exitosamente pilas de combustible de óxido sólido con electrolitos de ceria dopada con Gd, Ce1-xGdxO2-y (CGO soportados sobre un ánodo formado por un cermet de Ni/CGO. Dichas pilas se han

  4. [The ultrastructure of Sertoli cells and spermatogonia in the rats exposed to radiation under conditions of therapeutic and prophylactic application of low-intensity electromagnetic emission].

    Science.gov (United States)

    Korolev, Y N; Bobrovnitskii, I P; Geniatulina, M S; Nikulina, L A; Mikhailik, L V

    2018-04-09

    it has been demonstrated in various experimental studies that radiation exposure produces a negative impact on the processes of spermatogenesis associated with the disturbances of the microcirculation processes in the testes and the development of cellular and intracellular disintegration expressed as destructive changes in the cells leading to their death. The objective of the present study was to detect the ultrastructural abnormalities in the cells of Sertoli and spermatogonia under conditions of their exposure to radiation and to identify the peculiarities of their regeneration under the influence of the therapeutic and prophylactic application of low-intensity ultra-high frequency (UHF) electromagnetic radiation (EMR) and low-intensity low-frequency magnetic field (MF). The experiments were carried out on 28 non-pedigree mature male rats with the body weight 180-220 g that were divided into four groups. The first study group was comprised of the animals exposed to radiation followed by the application of low-intensity ultra-high frequency UHF electromagnetic radiation EMR. The rats in the second study group experienced effects of radiation and low-intensity low-frequency MF. The animals of the third (control) group were exposed to radiation alone, and those comprising the fourth group 1 (only radiation exposure) were considered to be intact. The studies with the use of electron microscopy showed that the therapeutic and prophylactic application of low-intensity ultra-high frequency (UHF) electromagnetic radiation and low-intensity low-frequency magnetic field caused the decrease in the number and the severity of post-radiation defects in the treated cells together with the increase of the number and size of mitochondria as well as hyperplasia of ribosomes; moreover, it promoted cellular and intracellular regeneration. UHF electromagnetic radiation had a more pronounced stimulating effect on the regeneration processes as compared with low-frequency MF

  5. Single Restorations in the Resorbed Posterior Mandible Supported by 6-mm Implants : A 1-Year Prospective Case Series Study

    NARCIS (Netherlands)

    Gulje, Felix L.; Raghoebar, Gerry M.; Vissink, Arjan; Meijer, Henny J. A.

    2015-01-01

    PurposeThe aim of this prospective case series study was to assess the clinical performance of single restorations in the posterior mandible supported by 6-mm implants. Materials and MethodsTwenty-one consecutive patients with one or more missing premolars or molars in the posterior mandible and

  6. Centering Single Cells in Microgels via Delayed Crosslinking Supports Long-Term 3D Culture by Preventing Cell Escape

    NARCIS (Netherlands)

    Kamperman, Tom; Henke, Sieger; Visser, Claas Willem; Karperien, Marcel; Leijten, Jeroen

    2017-01-01

    Single-cell-laden microgels support physiological 3D culture conditions while enabling straightforward handling and high-resolution readouts of individual cells. However, their widespread adoption for long-term cultures is limited by cell escape. In this work, it is demonstrated that cell escape is

  7. Influence of restorative materials on color of implant-supported single crowns in esthetic zone: A spectrophotometric evaluation

    DEFF Research Database (Denmark)

    M., Peng; W.-J., Zhao; M., Hosseini

    2017-01-01

    Restorations of 98 implant-supported single crowns in anterior maxillary area were divided into 5 groups: zirconia abutment, titanium abutment, and gold/gold hue abutment with zirconia coping, respectively, and titanium abutment with metal coping as well as gold/gold hue abutment with metal copin...

  8. On the freezing behavior and diffusion of water in proximity to single-supported zwitterionic and anionic bilayer lipid membranes

    DEFF Research Database (Denmark)

    Miskowiec, A.; Buck, Z. N.; Brown, M. C.

    2014-01-01

    We compare the freezing/melting behavior of water hydrating single-supported bilayers of a zwitterionic lipid DMPC with that of an anionic lipid DMPG. For both membranes, the temperature dependence of the elastically scattered neutron intensity indicates distinct water types undergoing...

  9. A 5-year prospective study of single-tooth replacements supported by the Astra Tech implant: a pilot study

    DEFF Research Database (Denmark)

    Gotfredsen, Klaus

    2004-01-01

    BACKGROUND: Implant-supported single-tooth replacements are an increasingly used method to replace teeth, especially in young patients. Therefore, long-term validation of different treatment modalities with different implant systems is of great importance. PURPOSE: The aim of the present study...... was to make a biologic, technical, and aesthetic evaluation of single-tooth replacement supported by the Astra Tech implant (Astra Tech AB, Mölndal, Sweden) during a 5-year period. MATERIALS AND METHODS: Twenty patients were divided into two consecutively treated groups. In group A the implants were placed...... "early" in the extraction sockets, and standard single-tooth abutments were used. In group B the implants were placed "delayed," and preparable abutments were used. Clinical examinations including registration of plaque, bleeding, crown lengths, soft tissue marginal level, papilla height, complications...

  10. Weighting and Aggregation in Life Cycle Assessment: Do Present Aggregated Single Scores Provide Correct Decision Support?

    DEFF Research Database (Denmark)

    Kalbar, Pradip; Birkved, Morten; Nygaard, Simon Elsborg

    2016-01-01

    approach was adopted to facilitate identification of three main problems related to the single-score calculation approach. The prevailing ReCiPe single-score calculation method does not account for either the effect of so-called dominating alternatives (i.e., alternatives having high values across all...... endpoints) or the interdependency of the indicators being aggregated. It was also found that the simple linear weighted sum method, presently used for obtaining single scores, is not capable of accounting for the effect of weighting schemes and thus cannot realistically represent stakeholders' perspectives...

  11. A high performance catalyst for methane conversion to methanol: graphene supported single atom Co.

    Science.gov (United States)

    Yuan, Jinyun; Zhang, Wenhua; Li, Xingxing; Yang, Jinlong

    2018-02-27

    Employing first principles calculations, we show a two-step reaction mechanism for direct methane oxidation to methanol over a single atom Co-embedded graphene (Gr) catalyst, with N 2 O as the O-donor molecule. C-H activation is the rate-limiting step. The high reaction activity and selectivity under mild conditions were predicted for this catalyst.

  12. Synthesis of Single-Walled Carbon Nanotubes: Effects of Active Metals, Catalyst Supports, and Metal Loading Percentage

    Directory of Open Access Journals (Sweden)

    Wei-Wen Liu

    2013-01-01

    Full Text Available The effects of active metals, catalyst supports, and metal loading percentage on the formation of single-walled carbon nanotubes (SWNTs were studied. In particular, iron, cobalt, and nickel were investigated for SWNTs synthesis. Iron was found to grow better-quality SWNTs compared to cobalt and nickel. To study the effect of catalyst supports, magnesium oxide, silicon oxide, and aluminium oxide were chosen for iron. Among the studied supports, MgO was identified to be a suitable support for iron as it produced SWNTs with better graphitisation determined by Raman analysis. Increasing the iron loading decreased the quality of SWNTs due to extensive agglomeration of the iron particles. Thus, lower metal loading percentage is preferred to grow better-quality SWNTs with uniform diameters.

  13. Novel Anodic Catalyst Support for Direct Methanol Fuel Cell: Characterizations and Single-Cell Performances.

    Science.gov (United States)

    Abdullah, N; Kamarudin, S K; Shyuan, L K

    2018-04-03

    This study introduces a novel titanium dioxide carbon nanofiber (TiO 2 -CNF) support for anodic catalyst in direct methanol fuel cell. The catalytic synthesis process involves several methods, namely the sol-gel, electrospinning, and deposition methods. The synthesized electrocatalyst is compared with other three electrocatalysts with different types of support. All of these electrocatalysts differ based on a number of physical and electrochemical characteristics. Experimental results show that the TiO 2 -CNF support gave the highest current density at 345.64 mA mg catalyst -1 , which is equivalent to 5.54-fold that of carbon support while the power density is almost double that of the commercial electrocatalyst.

  14. Thermal and structural performance of a single tube support post for the Superconducting Super Collider dipole magnet cryostat

    International Nuclear Information System (INIS)

    Boroski, W.N.; Nicol, T.H.; Ruschman, M.K.; Schoo, C.J.

    1993-07-01

    The reentrant support post currently incorporated in the Superconducting Super Collider (SSC) dipole cryostat has been shown to meet the structural and thermal requirements of the cryostat, both in prototype magnet assemblies and through component testing. However, the reentrant post design has two major drawbacks: tight dimensional control on all components, and cost driven by these tolerance constraints and a complex assembly procedure. A single tube support post has been developed as an alternative to the reentrant post design. Several prototype assemblies have been fabricated and subjected to structural testing. Compressive, tensile, and bending forces were applied to each assembly with deflection measured at several locations. A prototype support post has also been thermally evaluated in a heat leak measurement facility. Heat load to 4.2 K was measured with the intermediate post intercept operating at various temperatures while thermometers positioned along the conductive path of the post mapped thermal gradients. Results from these measurements indicate the single tube support post meets the design criteria for the SSC dipole magnet cryostat support system

  15. A 1-year randomised controlled trial comparing zirconia versus metal-ceramic implant supported single-tooth restorations

    DEFF Research Database (Denmark)

    Hosseini, Mandana; Worsaae, Nils; Schiødt, Morten

    2011-01-01

    PURPOSE: To compare the biological, technical and aesthetic outcomes of single implant-supported all-ceramic versus metal-ceramic crowns. MATERIALS AND METHODS: Thirty-six patients with premolar agenesis were randomly treated with 38 all-ceramic (AC) and 37 metal-ceramic (MC) implant......-supported single-tooth restorations. A quasi-randomisation of consecutively included restorations in patients with one or more implants was used, i.e. a combination of parallel group (for 13 patients with one restoration) and split-mouth (for 23 patients with =2 restorations). All patients were recalled......, by blinded assessors. RESULTS: One-year after loading, no patient dropped out and no implant failed, though one MC restoration had to be remade. The marginal bone loss was not significantly different between AC and MC restorations (AC: mean 0.08 mm, SD 0.25; MC: mean 0.10 mm, SD 0.17). Seven out of 10...

  16. A single blind randomized control trial on support groups for Chinese persons with mild dementia

    Directory of Open Access Journals (Sweden)

    Young DKW

    2014-12-01

    Full Text Available Daniel KW Young,1 Timothy CY Kwok,2 Petrus YN Ng1 1Department of Social Work, Hong Kong Baptist University, Kowloon Tong, Hong Kong; 2Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong Purpose: Persons with mild dementia experience multiple losses and manifest depressive symptoms. This research study aimed to evaluate the effectiveness of a support group led by a social worker for Chinese persons with mild dementia. Research methods: Participants were randomly assigned to either a ten-session support group or a control group. Standardized assessment tools were used for data collection at pretreatment and post-treatment periods by a research assistant who was kept blind to the group assignment of the participants. Upon completion of the study, 20 treatment group participants and 16 control group participants completed all assessments. Results: At baseline, the treatment and control groups did not show any significant difference on all demographic variables, as well as on all baseline measures; over one-half (59% of all the participants reported having depression, as assessed by a Chinese Geriatric Depression Scale score ≥8. After completing the support group, the depressive mood of the treatment group participants reduced from 8.83 (standard deviation =2.48 to 7.35 (standard deviation =2.18, which was significant (Wilcoxon signed-rank test; P=0.017, P<0.05, while the control group’s participants did not show any significant change. Conclusion: This present study supports the efficacy and effectiveness of the support group for persons with mild dementia in Chinese society. In particular, this present study shows that a support group can reduce depressive symptoms for participants. Keywords: support group, mild dementia, Chinese, depression

  17. SSC 50 MM collider dipole cryostat single tube support post conceptual design and analysis

    International Nuclear Information System (INIS)

    Nicol, T.H.

    1992-01-01

    Superconducting Super Collider (SSC) dipole magnet cold masses are connected to the cryostat vacuum vessel at five places equally spaced along their length. Five supports limit sag of the cold assembly due to its own weight to a level consistent with the final magnet alignment specifications. The design essentially consists of two composite tubes nested within each other as a means of maximizing the thermal path length. In addition it provides an ideal way to utilize materials best suited for the temperature range over which they must operate. Filament wound S-glass is used between 300K and 80K. Filament wound graphite fiber is used between 80K and 20K and between 20K and 4.5K. S-glass is a better thermal performer above approximately 40K. Graphite composites are ideally suited for operation below 40K. The designs for the 50 mm reentrant supports are well documented in the literature. The current design of the reentrant support has two major drawbacks. First, it requires very tight dimensional control on all components; composite tubes and metal attachment parts. Second, it is expensive, with cost being driven by both the tolerance constraints and by a complex assembly procedure. It seems clear that production magnets will require a support structure which is considerably less expensive than that which is currently used. It seems clear that a design alternate for reentrant support posts will be required for production dipoles primarily due to their cost. It seems less clear that injection molded composite materials are the ideal choice. This report describes the conceptual design for a support post whose function is identical to that of the current reentrant design, which requires very few modifications to surrounding cryostat components, is thermally equivalent to the current 50 mm support post, and is nearly equivalent structurally

  18. A technique for fabricating single screw-retained implant-supported interim crowns in conjunction with implant surgery.

    Science.gov (United States)

    McRory, M Eric; Cagna, David R

    2014-06-01

    This article presents an intraoral technique for fabricating single screw-retained implant-supported interim crowns immediately after surgical implant placement in extraction sites. The technique may be used with any implant system that provides a provisional abutment or an open-tray impression coping that can be modified for use as a provisional abutment. Copyright © 2014 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  19. Single-Site Tetracoordinated Aluminum Hydride Supported on Mesoporous Silica. From Dream to Reality!

    KAUST Repository

    Werghi, Baraa

    2016-09-26

    The reaction of mesoporous silica (SBA15) dehydroxylated at 700 °C with diisobutylaluminum hydride, i-Bu2AlH, gives after thermal treatment a single-site tetrahedral aluminum hydride with high selectivity. The starting aluminum isobutyl and the final aluminum hydride have been fully characterized by FT-IR, advanced SS NMR spectroscopy (1H, 13C, multiple quanta (MQ) 2D 1H-1H, and 27Al), and elemental analysis, while DFT calculations provide a rationalization of the occurring reactivity. Trimeric i-Bu2AlH reacts selectively with surface silanols without affecting the siloxane bridges. Its analogous hydride catalyzes ethylene polymerization. Indeed, catalytic tests show that this single aluminum hydride site is active in the production of a high-density polyethylene (HDPE). © 2016 American Chemical Society.

  20. A Forward Dynamic Modelling Investigation of Cause-and-Effect Relationships in Single Support Phase of Human Walking

    Directory of Open Access Journals (Sweden)

    Michael McGrath

    2015-01-01

    Full Text Available Mathematical gait models often fall into one of two categories: simple and complex. There is a large leap in complexity between model types, meaning the effects of individual gait mechanisms get overlooked. This study investigated the cause-and-effect relationships between gait mechanisms and resulting kinematics and kinetics, using a sequence of mathematical models of increasing complexity. The focus was on sagittal plane and single support only. Starting with an inverted pendulum (IP, extended to include a HAT (head-arms-trunk segment and an actuated hip moment, further complexities were added one-by-one. These were a knee joint, an ankle joint with a static foot, heel rise, and finally a swing leg. The presence of a knee joint and an ankle moment (during foot flat were shown to largely influence the initial peak in the vertical GRF curve. The second peak in this curve was achieved through a combination of heel rise and the presence of a swing leg. Heel rise was also shown to reduce errors in the horizontal GRF prediction in the second half of single support. The swing leg is important for centre-of-mass (CM deceleration in late single support. These findings provide evidence for the specific effects of each gait mechanism.

  1. A single protofilament is sufficient to support unidirectional walking of dynein and kinesin.

    Directory of Open Access Journals (Sweden)

    Keitaro Shibata

    Full Text Available Cytoplasmic dynein and kinesin are two-headed microtubule motor proteins that move in opposite directions on microtubules. It is known that kinesin steps by a 'hand-over-hand' mechanism, but it is unclear by which mechanism dynein steps. Because dynein has a completely different structure from that of kinesin and its head is massive, it is suspected that dynein uses multiple protofilaments of microtubules for walking. One way to test this is to ask whether dynein can step along a single protofilament. Here, we examined dynein and kinesin motility on zinc-induced tubulin sheets (zinc-sheets which have only one protofilament available as a track for motor proteins. Single molecules of both dynein and kinesin moved at similar velocities on zinc-sheets compared to microtubules, clearly demonstrating that dynein and kinesin can walk on a single protofilament and multiple rows of parallel protofilaments are not essential for their motility. Considering the size and the motile properties of dynein, we suggest that dynein may step by an inchworm mechanism rather than a hand-over-hand mechanism.

  2. Depression, social support, and clinical outcomes following lung transplantation: a single-center cohort study.

    Science.gov (United States)

    Smith, Patrick J; Snyder, Laurie D; Palmer, Scott M; Hoffman, Benson M; Stonerock, Gregory L; Ingle, Krista K; Saulino, Caroline K; Blumenthal, James A

    2017-11-12

    Depressive symptoms are common among lung transplant candidates and have been associated with poorer clinical outcomes in some studies. Previous studies have been plagued by methodologic problems, including small sample sizes, few clinical events, and uncontrolled confounders, particularly perioperative complications. In addition, few studies have examined social support as a potential protective factor. We therefore examined the association between pretransplant depressive symptoms, social support, and mortality in a large sample of lung transplant recipients. As a secondary aim, we also examined the associations between psychosocial factors, perioperative outcomes [indexed by hospital length of stay (LOS)], and mortality. We hypothesized that depression would be associated with longer LOS and that the association between depression, social support, and mortality would be moderated by LOS. Participants included lung transplant recipients, transplanted at Duke University Medical Center from January 2009 to December 2014. Depressive symptoms were evaluated using the Beck Depression Inventory (BDI-II) and social support using the Perceived Social Support Scale (PSSS). Medical risk factors included forced vital capacity (FVC), partial pressure of carbon dioxide (PCO 2 ), donor age, acute rejection, and transplant type. Functional status was assessed using six-minute walk distance (6MWD). We also controlled for demographic factors, including age, gender, and native disease. Transplant hospitalization LOS was examined as a marker of perioperative clinical outcomes. Participants included 273 lung recipients (174 restrictive, 67 obstructive, 26 cystic fibrosis, and six "other"). Pretransplant depressive symptoms were common, with 56 participants (21%) exhibiting clinically elevated levels (BDI-II ≥ 14). Greater depressive symptoms were associated with longer LOS [adjusted b = 0.20 (2 days per 7-point higher BDI-II score), P social support (P social support were

  3. Fracture Strength and Failure Mode of Maxillary Implant-Supported Provisional Single Crowns : A Comparison of Composite Resin Crowns Fabricated Directly Over PEEK Abutments and Solid Titanium Abutments

    NARCIS (Netherlands)

    Santing, H.J.; Meijer, Henny J.A.; Raghoebar, G.M.; Ozcan, M.

    2012-01-01

    Background: Polyetheretherketone (PEEK) temporary abutments have been recently introduced for making implant-supported provisional single crowns. Little information is available in the dental literature on the durability of provisional implant-supported restorations. Purpose: The objectives of this

  4. Carrier mediated transport through supported liquid membranes; determination of transport parameters from a single transport experiment

    NARCIS (Netherlands)

    Chrisstoffels, L.A.J.; Struijk, Wilhelmina; de Jong, Feike; Reinhoudt, David

    1996-01-01

    This paper describes a time-dependent transport model for carrier assisted cation transport through supported liquid membranes. The model describes the flux of salt as a function of time and two parameters viz. the diffusion coefficient of the cation complex (D), and the extraction constant (Kex).

  5. Extracorporeal Membrane Oxygenation Support in Neonates: A Single Medical Center Experience in Taiwan

    Directory of Open Access Journals (Sweden)

    Chi-Man Kuok

    2017-08-01

    Conclusion: This is the first report for ECMO in neonatal disease in Taiwan. We achieved an overall survival rate of 59.2% with good neurological outcomes in this 10-year experience. ECMO could be a useful transportation tool for critical neonates who have a poor response to ventilator support.

  6. Protein-Nanocrystal Conjugates Support a Single Filament Polymerization Model in R1 Plasmid Segregation

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Charina L.; Claridge, Shelley A.; Garner, Ethan C.; Alivisatos, A. Paul; Mullins, R. Dyche

    2008-07-15

    To ensure inheritance by daughter cells, many low-copy number bacterial plasmids, including the R1 drug-resistance plasmid, encode their own DNA segregation systems. The par operon of plasmid R1 directs construction of a simple spindle structure that converts free energy of polymerization of an actin-like protein, ParM, into work required to move sister plasmids to opposite poles of rod-shaped cells. The structures of individual components have been solved, but little is known about the ultrastructure of the R1 spindle. To determine the number of ParM filaments in a minimal R1 spindle, we used DNA-gold nanocrystal conjugates as mimics of the R1 plasmid. Wefound that each end of a single polar ParM filament binds to a single ParR/parC-gold complex, consistent with the idea that ParM filaments bind in the hollow core of the ParR/parC ring complex. Our results further suggest that multifilament spindles observed in vivo are associated with clusters of plasmidssegregating as a unit.

  7. Inverter Anti-Islanding with Advanced Grid Support in Single- and Multi-Inverter Islands

    Energy Technology Data Exchange (ETDEWEB)

    Hoke, Andy

    2016-08-16

    As PV and other DER systems are connected to the grid at increased penetration levels, island detection may become more challenging for two reasons: 1. In islands containing many DERs, active inverter-based anti-islanding methods may have more difficulty detecting islands because each individual inverter's efforts to detect the island may be interfered with by the other inverters in the island. 2. The increasing numbers of DERs are leading to new requirements that DERs ride through grid disturbances and even actively try to regulate grid voltage and frequency back towards nominal operating conditions. These new grid support requirements may directly or indirectly interfere with anti-islanding controls. This report describes a series of tests designed to examine the impacts of both grid support functions and multi-inverter islands on anti-islanding effectiveness.

  8. Supportive text messaging for depression and comorbid alcohol use disorder: single-blind randomised trial.

    Science.gov (United States)

    Agyapong, Vincent I O; Ahern, Sinead; McLoughlin, Declan M; Farren, Conor K

    2012-12-10

    Mobile phone text message technology has the potential to improve outcomes for patients with depression and co-morbid Alcohol Use Disorder (AUD). To perform a randomised rater-blinded trial to explore the effects of supportive text messages on mood and abstinence outcomes for patients with depression and co-morbid AUD. Participants (n=54) with a DSM IV diagnosis of unipolar depression and AUD who completed an in-patient dual diagnosis treatment programme were randomised to receive twice daily supportive text messages (n=26) or a fortnightly thank you text message (n=28) for three months. Primary outcome measures were Beck's Depression Inventory (BDI-II) scores and Cumulative Abstinence Duration (CAD) in days at three months. NCT0137868. There was a statistically significant difference in three month BDI-II scores between the intervention and control groups; 8.5 (SD=8.0) vs. 16.7 (SD=10.3) respectively after adjusting for the baseline scores, F (1, 49)=9.54, p=0.003, η(p)(2)=0.17. The mean difference in change BDI-II scores was -7.9 (95% CI -13.06 to -2.76, Cohen'sd=0.85). There was a trend for a greater CAD in the text message group than the control group: 88.3 (SD=6.2) vs. 79.3 (SD=24.1), t=1.78, df=48, p=0.08. Limitations of the study include the small sample size, the potential for loss of rater blinding and the lack of long term follow-up to determine the longer term effects of the intervention. Supportive text messages have the potential to improve outcomes for patients with comorbid depression and alcohol dependency syndrome. Copyright © 2012 Elsevier B.V. All rights reserved.

  9. Fracture mode during cyclic loading of implant-supported single-tooth restorations

    DEFF Research Database (Denmark)

    Hosseini, Mandana; Kleven, Erik; Gotfredsen, Klaus

    2012-01-01

    restorations of zirconia abutment-retained crowns with zirconia copings veneered with glass-ceramics (n=8) and feldspathic ceramics (n=8). The control group was composed of 16 metal ceramic restorations of titanium abutment-retained crowns with gold alloy copings veneered with glass (n=8) and feldspathic......STATEMENT OF PROBLEM: Fracture of veneering ceramics in zirconia-based restorations has frequently been reported. Investigation of the fracture mode of implant-supported ceramic restorations by using clinically relevant laboratory protocols is needed. PURPOSE: This study compared the mode...... and resisted more cyclic loads than the ceramic restorations, particularly when the metal ceramic crowns were veneered with glass-ceramics....

  10. The Effect of Peers Support on Postpartum Depression: A Single-Blind Randomized Clinical Trial

    Directory of Open Access Journals (Sweden)

    Mahin Kamalifard

    2013-08-01

    Full Text Available Introduction: Postpartum depression and its consequences not only involve mothers and their children but it will also affect their families. Therefore, this study aimed to investigate the effect of mothers receiving peer support on postpartum depression. Methods: 100 eligible primiparous women participated in a randomized clinical trial. The intervention group received phone calls by their peers from the last three months of pregnancy until two months after delivery. The control group only had access to routine care. Both groups in the second month after delivery were checked regarding depression using Edinburgh Postnatal Depression Scale. Data analysis was performed using independent t-test, chi-square test and covariance analysis. Results: Mean depression score before intervention was 13.92 (3.23 in the control group and 14.06 (3.12 in the intervention group. In week 8 after delivery, mean score of depression in control group was 13.29 (4.08 but in the intervention group it was reduced to 10.25 (4.18. Difference in the reduction of mean postpartum depression score between the two groups showed statistically significant difference (p < 0.001. Conclusion: This study showed that peer support was effective in the prevention of postpartum depression, therefore, it is recommended to be used in the reduction of postpartum depression.

  11. Water Adsorption and Dissociation on Ceria-Supported Single-Atom Catalysts: A First-Principles DFT+U Investigation.

    Science.gov (United States)

    Han, Zhong-Kang; Gao, Yi

    2016-02-01

    Single-atom catalysts have attracted wide attention owing to their extremely high atom efficiency and activities. In this paper, we applied density functional theory with the inclusion of the on-site Coulomb interaction (DFT+U) to investigate water adsorption and dissociation on clean CeO 2 (111) surfaces and single transition metal atoms (STMAs) adsorbed on the CeO 2 (111) surface. It is found that the most stable water configuration is molecular adsorption on the clean CeO 2 (111) surface and dissociative adsorption on STMA/CeO 2 (111) surfaces, respectively. In addition, our results indicate that the more the electrons that transfer from STMA to the ceria substrate, the stronger the binding energies between the STMA and ceria surfaces. A linear relationship is identified between the water dissociation barriers and the d band centers of STMA, known as the generalized Brønsted-Evans-Polanyi principle. By combining the oxygen spillovers, single-atom dispersion stabilities, and water dissociation barriers, Zn, Cr, and V are identified as potential candidates for the future design of ceria-supported single-atom catalysts for reactions in which the dissociation of water plays an important role, such as the water-gas shift reaction. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Influence of Restorative Materials on Color of Implant-Supported Single Crowns in Esthetic Zone: A Spectrophotometric Evaluation

    Science.gov (United States)

    Zhao, Wei-Jie; Hosseini, Mandana; Zhou, Wen-Juan; Xiao, Ting

    2017-01-01

    Restorations of 98 implant-supported single crowns in anterior maxillary area were divided into 5 groups: zirconia abutment, titanium abutment, and gold/gold hue abutment with zirconia coping, respectively, and titanium abutment with metal coping as well as gold/gold hue abutment with metal coping. A reflectance spectrophotometer was used to evaluate the color difference between the implant crowns and contralateral/neighboring teeth, as well as the color difference between the peri-implant soft tissue and the natural marginal mucosa. The mucosal discoloration score was used for subjective evaluation of the esthetic outcome of soft tissue around implant-supported single crowns in the anterior zone, and the crown color match score was used for subjective evaluation of the esthetic outcome of implant-supported restoration. ANOVA analysis was used to compare the differences among groups and Spearman correlation was used to test the relationships. A gold/gold hue abutment with zirconia coping was the best choice for an esthetic crown and the all-ceramic combination was the best for peri-implant soft tissue. Significant correlation was found between the spectrophotometric color difference of peri-implant soft tissue and mucosal discoloration score, while no significant correlation was found between the total spectrophotometric color difference of implant crown and crown color match score. PMID:29349075

  13. Influence of Restorative Materials on Color of Implant-Supported Single Crowns in Esthetic Zone: A Spectrophotometric Evaluation

    Directory of Open Access Journals (Sweden)

    Min Peng

    2017-01-01

    Full Text Available Restorations of 98 implant-supported single crowns in anterior maxillary area were divided into 5 groups: zirconia abutment, titanium abutment, and gold/gold hue abutment with zirconia coping, respectively, and titanium abutment with metal coping as well as gold/gold hue abutment with metal coping. A reflectance spectrophotometer was used to evaluate the color difference between the implant crowns and contralateral/neighboring teeth, as well as the color difference between the peri-implant soft tissue and the natural marginal mucosa. The mucosal discoloration score was used for subjective evaluation of the esthetic outcome of soft tissue around implant-supported single crowns in the anterior zone, and the crown color match score was used for subjective evaluation of the esthetic outcome of implant-supported restoration. ANOVA analysis was used to compare the differences among groups and Spearman correlation was used to test the relationships. A gold/gold hue abutment with zirconia coping was the best choice for an esthetic crown and the all-ceramic combination was the best for peri-implant soft tissue. Significant correlation was found between the spectrophotometric color difference of peri-implant soft tissue and mucosal discoloration score, while no significant correlation was found between the total spectrophotometric color difference of implant crown and crown color match score.

  14. Functions and requirements for subsurface barriers used in support of single-shell tank waste retrieval

    International Nuclear Information System (INIS)

    Lowe, S.S.

    1993-01-01

    The mission of the Tank Waste Remediation System (TWRS) Program is to store, treat, and immobilize highly radioactive Hanford waste in an environmentally sound, safe, and cost-effective manner. The scope of the TWRS Program includes project and program activities for receiving, storing, maintaining, treating, and disposing onsite, or packaging for offsite disposal, all Hanford tank waste. Hanford tank waste includes the contents of 149 single-shell tanks (SSTs) and 28 double-shell tanks (DSTs), plus any new waste added to these facilities, and all encapsulated cesium and strontium stored onsite and returned from offsite users. A key element of the TWRS Program is retrieval of the waste in the SSTs. The waste stored in these underground tanks must be removed in order to minimize environmental, safety, and health risks associated with continuing waste storage. Subsurface barriers are being considered as a means to mitigate the effects of tank leaks including those occurring during SST waste retrieval. The functions to be performed by subsurface barriers based on their role in retrieving waste from the SSTs are described, and the requirements which constrain their application are identified. These functions and requirements together define the functional baseline for subsurface barriers

  15. Grid Frequency Support by Single-Phase Electric Vehicles Employing an Innovative Virtual Inertia Controller

    DEFF Research Database (Denmark)

    Rezkalla, Michel M.N.; Zecchino, Antonio; Pertl, Michael

    2016-01-01

    to limit the rate of change of frequency of power systems, thus, improving frequency dynamics. Electric vehicles (EVs) can represent a reliable solution to enhance frequency stability due to their fast response and capability to provide a large amount of aggregated power. On one hand, EVs are capable...... of adjusting the battery charging process (i.e., power flow) according to pre-defined algorithms. On the other hand, in case of islanded operation (i.e., low inertia), some of the EV's technical constraints might cause oscillations. This study presents two control algorithms which show that the EVs are capable...... of providing virtual inertia support. The first controller employs a traditional droop control, while the second one is equipped with an innovative control algorithm to eliminate likely oscillations. It is shown that, the proposed innovative control algorithm compared to the traditional droop control, assures...

  16. Support vector machines and evolutionary algorithms for classification single or together?

    CERN Document Server

    Stoean, Catalin

    2014-01-01

    When discussing classification, support vector machines are known to be a capable and efficient technique to learn and predict with high accuracy within a quick time frame. Yet, their black box means to do so make the practical users quite circumspect about relying on it, without much understanding of the how and why of its predictions. The question raised in this book is how can this ‘masked hero’ be made more comprehensible and friendly to the public: provide a surrogate model for its hidden optimization engine, replace the method completely or appoint a more friendly approach to tag along and offer the much desired explanations? Evolutionary algorithms can do all these and this book presents such possibilities of achieving high accuracy, comprehensibility, reasonable runtime as well as unconstrained performance.

  17. Cemented versus screw-retained implant-supported single-tooth crowns: a 10-year randomised controlled trial.

    Science.gov (United States)

    Vigolo, Paolo; Mutinelli, Sabrina; Givani, Andrea; Stellini, Edoardo

    2012-01-01

    The purpose of this randomised controlled trial was to compare the long-term clinical outcome of cemented and screw-retained implant-supported single-tooth crowns. Eighteen consecutive patients presenting with single-tooth bilateral edentulous sites in the canine/molar region with adequate bone width, similar bone height at the implant sites, and an occlusal scheme that allowed for the establishment of identical occlusal cusp/fossa contacts were treated. Each patient received two identical implants according to a split-mouth design. One side was randomly selected to be restored with a cemented implant-supported single crown, and the other was restored with a screw-retained implant-supported single crown. Outcome measures were implant success, complications, marginal bone levels and peri-implant soft tissue health. Ten years after initial loading, 2 patients moved away and were lost to follow-up. Two implants placed in the same patient failed 5 years after their insertion; the remaining 30 implants survived, resulting in a cumulative implant success rate of 93.7%. No complication occurred. The mean marginal bone resorption at 10 years after implant placement, measured on intraoral radiographs, was 1.1 ± 0.2 mm for both types of restorations. There were no statistically significant differences between the two groups with respect to peri-implant marginal bone level at the 10-year follow-up appointment (T2) (P = 0.58); at the 4-year follow-up appointment (T1) a statistically significant difference was observed (P = 0.01), but this was not considered clinically relevant (mean difference: -0.06 mm). The status of the soft tissue around the implants remained stable over the evaluation period. No statistically significant difference was identified for the facial keratinised gingiva between the two groups at T1 (P = 0.10) or at T2 (P = 0.07). Within the limitations of this study, the results indicate that there was no evidence of a significant difference in the clinical

  18. Functional aspects of treatment with implant-supported single crowns: a quality control study in subjects with tooth agenesis

    DEFF Research Database (Denmark)

    Goshima, Kenichi; Lexner, Michala O; Thomsen, Carsten Eckhart

    2010-01-01

    after implant placement shortly before crown cementation, and again 1 month after cementation. It consisted of questionnaires [including Oral Health Impact Profile (OHIP-49)] and functional examination with plastic strips, the Dental Prescale Film and the Occluzer system, Xylitol color-changeable gum......BACKGROUND: No comprehensive patient-centered and clinical evaluations of the functional effect of treatment with implant-supported single crowns (ISSC) have been reported previously. OBJECTIVE: To investigate whether and how treatment with ISSC affects masticatory function and Oral Health...

  19. Single Pot Selective Hydrogenation of Furfural to 2-Methylfuran Over Carbon Supported Iridium Catalysts

    KAUST Repository

    Date, Nandan S

    2018-03-20

    Various iridium supported carbon catalysts were prepared and screened for direct hydrogenation of furfural (FFR) to 2-methyl furan (2-MF). Amongest these, 5% Ir/C showed excellent results with complete FFR conversion and highest selectivity of 95% to 2-MF at very low H2 pressure of 100 psig. Metallic (Iro) and oxide ( IrO2) phases of Ir catalyzed first step hydrogenation involving FFR to FAL and subsequent hydrogenation to 2-MF,respecively. This was confirmed by XPS analysis and some controlled experiments. At low temperature of 140 oC, almost equal selectivities of FAL (42%) and 2-MF (43%) were observed, while higher temperature (220oC) favored selective hydrodeoxygenation. At optimized temperature, 2-MF formed selectively while higher pressure and higher catalyst loading favored ring hydrogenation of furfural rather than side chain hydrogenation. With combination of several control experimental results and detailed catalyst characterization, a plausible reaction pathway has been proposed for selective formation of 2-MF. The selectivity to various other products in FFR hydrogenation can be manipulated by tailoring the reaction conditions over the same catalyst.

  20. Monolithic lithium-disilicate single crowns supported by zirconia oral implants: three-year results of a prospective cohort study.

    Science.gov (United States)

    Spies, Benedikt Christopher; Patzelt, Sebastian Berthold Maximilian; Vach, Kirstin; Kohal, Ralf-Joachim

    2016-09-01

    To determine the survival and success rate of CAD/CAM-fabricated monolithic lithium-disilicate crowns supported by zirconia oral implants after 3 years. Twenty-four patients in need of a single tooth replacement received a zirconia implant and were finally restored with 24 single crowns (SCs) ground out of pre-crystallized lithium-disilicate blanks. The restorations were adhesively cemented and evaluated using modified United States Public Health Service (USPHS) criteria. In case of clinically relevant defects that could be repaired to an acceptable level, SCs were regarded as surviving. Restorations with minor chippings, a small-area roughness (ø esthetics, sense, and speech. Monolithic lithium-disilicate SCs supported by zirconia implants showed promising survival and success rates after an observation period of 3 years. It remains to be seen whether the further observation period confirms this positive results. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  1. Single-layer ZnS supported on Au(111): A combined XPS, LEED, STM and DFT study

    Science.gov (United States)

    Deng, Xingyi; Sorescu, Dan C.; Lee, Junseok

    2017-04-01

    Single-layer of ZnS, consisting of one atomic layer of ZnS(111) plane, has been grown on Au(111) and characterized using X-ray photoelectron spectroscopy (XPS), low energy electron diffraction (LEED) and scanning tunneling microscopy (STM). While the LEED measurement indicates a coincidence structure of ZnS-(3×3)/Au(111)-(4×4), high resolution STM images reveal hexagonal unit cells of 6.7×6.7 Å2 and 11.6×11.6 Å2, corresponding to √3 and 3 times the unit cell of the ideal zincblende ZnS-(1×1), respectively, depending on the tunneling conditions. Calculations based on density functional theory (DFT) indicate a significantly reconstructed non-planar structure of ZnS single-layer on Au(111) with 2/3 of the S anions being located nearly in the plane of the Zn cations and the rest 1/3 of the S anions protruding above the Zn plane. The calculated STM image shows similar characteristics to those of the experimental STM image. Additionally, the DFT calculations reveal the different bonding nature of the S anions in ZnS single-layer supported on Au(111).

  2. Estimation of the distribution of low-intensity ultrasound mechanical index as a parameter affecting the proliferation of spermatogonia stem cells in vitro.

    Science.gov (United States)

    Moghaddam, Zeinab Hormozi; Mokhtari-Dizaji, Manijhe; Movahedin, Mansoureh; Ravari, Mohammad Ehsan

    2017-07-01

    Considering the use of physical and mechanical stimulation, such as low-intensity ultrasound for proliferation and differentiation of stem cells, it is essential to understand the physical and acoustical mechanisms of acoustic waves in vitro. Mechanical index is used for quantifying acoustic cavitation and the relationship between acoustic pressure and the frequency. In this study, modeling of the mechanical index was applied to provide treatment protocol and to understand the effective physical processes on reproducibility of stem cells. Due to low intensity of ultrasound, Rayleigh integral model has been used for acoustic pressure computation. The acoustic pressure and mechanical index equations are modeled and solved to estimate optimal mechanical index for 28, 40, 150kHz and 1MHz frequencies. This model are solved in different intensities and distances from transducer in cylindrical coordinates. Based on the results of the mechanical index, regions with threshold mechanical index of 0.7 were identified for extracting of radiation arrangement to cell medium. Acoustic pressure distribution along the axial and radial was extracted. In order to validate the results of the modeling, the acoustic pressure in the water and near field depth was measured by a piston hydrophone. Results of modeling and experiments show that the model is consistent well to experimental results with 0.91 and 0.90 correlation of coefficient (pmechanical index is more effective on enhancing the proliferation rate of the spermatogonia stem cells during the seven days of culture. In contrast, higher mechanical index has a harmful effect on the spermatogonial stem cells. Thus, considering cavitation threshold of different materials is necessary to find effective mechanical index ranges on proliferation for the used frequencies. This acoustic propagation model and ultrasound mechanical index assessments can be used with acceptable accuracy, for the extraction special arrangement of acoustic

  3. Fracture resistance of single-tooth implant-supported zirconia-based indirect composite-layered molar restorations.

    Science.gov (United States)

    Taguchi, Kohei; Komine, Futoshi; Fushiki, Ryosuke; Blatz, Markus B; Kamio, Shingo; Matsumura, Hideo

    2014-08-01

    This study evaluated the fracture resistance of single-tooth implant-supported zirconia-based indirect composite-layered molar restorations. Forty-four titanium abutments (GingiHue Post) were placed on dental implants (Osseotite Implant). Standardized single-tooth cement-retained implant-supported mandibular molar restorations were fabricated for each of four test groups (n = 11) as follows: porcelain-fused-to-metal crowns (PFM), zirconia-based all-ceramic crowns (ZAC), zirconia-based indirect composite-layered crowns primed with Estenia Opaque Primer for zirconia frameworks (ZIC-E), and zirconia-based indirect composite-layered crowns (ZIC). The crowns were luted with a glass-ionomer cement (Ketac Cem Easymix). Fracture resistance (N) was determined by force application of a perpendicular load to the crowns with a universal testing machine. One-way analysis of variance (ANOVA) and the Tukey's HSD test were used to assess differences in fracture resistance values (α = 0.05). Mean fracture resistances (SD) were 3.09 (0.22) kN, 3.11 (0.34) kN, 2.84 (0.21) kN, and 2.50 (0.36) kN for the PFM, ZAC, ZIC-E, and ZIC groups, respectively. Fracture resistance in the ZIC specimens was significantly lower (P zirconia-based indirect composite-layered molar crowns primed with Estenia Opaque Primer for zirconia frameworks (ZIC-E) is comparable to that of porcelain-fused-to-metal (PFM) and zirconia-based all-ceramic (ZAC) restorations. Application of Estenia Opaque Primer to zirconia ceramic framework provides superior fracture resistance in implant-supported zirconia-based indirect composite-layered molar crowns. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  4. Gait analysis following treadmill training with body weight support versus conventional physical therapy: a prospective randomized controlled single blind study.

    Science.gov (United States)

    Lucareli, P R; Lima, M O; Lima, F P S; de Almeida, J G; Brech, G C; D'Andréa Greve, J M

    2011-09-01

    Single-blind randomized, controlled clinical study. To evaluate, using kinematic gait analysis, the results obtained from gait training on a treadmill with body weight support versus those obtained with conventional gait training and physiotherapy. Thirty patients with sequelae from traumatic incomplete spinal cord injuries at least 12 months earlier; patients were able to walk and were classified according to motor function as ASIA (American Spinal Injury Association) impairment scale C or D. Patients were divided randomly into two groups of 15 patients by the drawing of opaque envelopes: group A (weight support) and group B (conventional). After an initial assessment, both groups underwent 30 sessions of gait training. Sessions occurred twice a week, lasted for 30 min each and continued for four months. All of the patients were evaluated by a single blinded examiner using movement analysis to measure angular and linear kinematic gait parameters. Six patients (three from group A and three from group B) were excluded because they attended fewer than 85% of the training sessions. There were no statistically significant differences in intra-group comparisons among the spatial-temporal variables in group B. In group A, the following significant differences in the studied spatial-temporal variables were observed: increases in velocity, distance, cadence, step length, swing phase and gait cycle duration, in addition to a reduction in stance phase. There were also no significant differences in intra-group comparisons among the angular variables in group B. However, group A achieved significant improvements in maximum hip extension and plantar flexion during stance. Gait training with body weight support was more effective than conventional physiotherapy for improving the spatial-temporal and kinematic gait parameters among patients with incomplete spinal cord injuries.

  5. Comparison of Marginal and Internal Adaptation of CAD/CAM and Conventional Cement Retained Implant-Supported Single Crowns.

    Science.gov (United States)

    Nejatidanesh, Farahnaz; Shakibamehr, Amir Hossein; Savabi, Omid

    2016-02-01

    To evaluate the accuracy of marginal and internal adaptation of 2 computer-aided design/computer-aided manufacturing (CAD/CAM) and 2 conventionally made cement retained implant-supported restorations. An abutment and its corresponding fixture analog (Astra Tech) were inserted in left central incisor area of a maxillary cast. Four types of implant-supported single restorations were fabricated on the abutment (n = 10): e.max CAD (Cerec AC system), zirconia-based (Cercon system), IPS e.max Press, and metal-ceramic restorations. The internal and marginal gaps of the studied groups were measured by replica method and stereomicroscope. Data were subjected to 1-way ANOVA and Scheffe post hoc tests (α = 0.05). Mean internal gaps of Cercon (59.48 ± 16.49 μm) and e.max Press (75.62 ± 26.92 μm) groups were significantly different from e.max CAD (120.29 ± 16.74 μm) group, but there was no significant difference between metal-ceramic restorations (89.65 ± 47.84 μm) and e.max CAD. The marginal gaps of e.max CAD (32.02 ± 10.38 μm) and Cercon restorations (34.26 ± 11.41 μm) were significantly superior from metal ceramics (59.19 ± 17.81 μm) and e.max press (74.99 ± 24.51 μm). Within the limitations of this study, it can be concluded that although the marginal and internal gaps of the studied implant-supported restorations were in the clinically acceptable range, single crowns made with CAD/CAM technology provide better marginal fit.

  6. An electrochemical impedance spectroscopy study of polymer electrolyte membrane fuel cells electrocatalyst single wall carbon nanohorns-supported.

    Science.gov (United States)

    Brandão, Lúcia; Boaventura, Marta; Passeira, Carolina; Gattia, Daniele Mirabile; Marazzi, Renzo; Antisari, Marco Vittori; Mendes, Adélio

    2011-10-01

    Electrochemical impedance spectroscopy (EIS) was used to study the polymer electrolyte membrane fuel cells (PEMFC) performance when using single wall carbon nanohorns (SWNH) to support Pt nanoparticles. Additionally, as-prepared and oxidized SWNH Pt-supports were compared with conventional carbon black. Two different oxidizing treatments were considered: oxygen flow at 500 degrees C and reflux in an acid solution at 85 degrees C. Both oxidizing treatments increased SWNH surface area; oxygen treatment increased surface area 4 times while acid treatment increased 2.6 times. The increase in surface area should be related to the opening access to the inner tube of SWNH. Acid treatment of SWNH increased chemical fragility and decreased electrocatalyst load in comparison with as-prepared SWNH. On the other hand, the oxygen treated SWNH sample allowed to obtain the highest electrocatalyst load. The use of as-prepared and oxygen treated SWNH showed in both cases catalytic activities 60% higher than using conventional carbon black as electrocatalyst support in PEMFC. Moreover, EIS analysis indicated that the major improvement in performance is related to the cathode kinetics in the as-prepared SWNH sample, while concerning the oxidized SWNH sample, the improvements are related to the electrokinetics in both anode and cathode electrodes. These improvements should be related with differences in the hydrophobic character between SWNH and carbon black.

  7. Mobile Phone Text Messages to Support Treatment Adherence in Adults With High Blood Pressure (SMS-Text Adherence Support [StAR]): A Single-Blind, Randomized Trial.

    Science.gov (United States)

    Bobrow, Kirsten; Farmer, Andrew J; Springer, David; Shanyinde, Milensu; Yu, Ly-Mee; Brennan, Thomas; Rayner, Brian; Namane, Mosedi; Steyn, Krisela; Tarassenko, Lionel; Levitt, Naomi

    2016-02-09

    We assessed the effect of automated treatment adherence support delivered via mobile phone short message system (SMS) text messages on blood pressure. In this pragmatic, single-blind, 3-arm, randomized trial (SMS-Text Adherence Support [StAR]) undertaken in South Africa, patients treated for high blood pressure were randomly allocated in a 1:1:1 ratio to information only, interactive SMS text messaging, or usual care. The primary outcome was change in systolic blood pressure at 12 months from baseline measured with a validated oscillometric device. All trial staff were masked to treatment allocation. Analyses were intention to treat. Between June 26, 2012, and November 23, 2012, 1372 participants were randomized to receive information-only SMS text messages (n=457), interactive SMS text messages (n=458), or usual care (n=457). Primary outcome data were available for 1256 participants (92%). At 12 months, the mean adjusted change in systolic blood pressure compared with usual care was -2.2 mm Hg (95% confidence interval, -4.4 to -0.04) with information-only SMS and -1.6 mm Hg (95% confidence interval, -3.7 to 0.6) with interactive SMS. Odds ratios for the proportion of participants with a blood pressure high blood pressure, we found a small reduction in systolic blood pressure control compared with usual care at 12 months. There was no evidence that an interactive intervention increased this effect. URL: http://www.clinicaltrials.gov. Unique identifier: NCT02019823. South African National Clinical Trials Register, number SANCTR DOH-27-1212-386; Pan Africa Trial Register, number PACTR201411000724141. © 2016 American Heart Association, Inc.

  8. Development and MASH full-scale crash testing of a high-mounting-height temporary single sign support with aluminum sign.

    Science.gov (United States)

    2013-03-01

    Work zone traffic control devices such as temporary single sign supports are a primary means to communicate : information to motorists in work zone areas. The Federal Highway Administration and the Manual on Uniform Traffic : Control Devices require ...

  9. Pt-Fe catalyst nanoparticles supported on single-wall carbon nanotubes: Direct synthesis and electrochemical performance for methanol oxidation

    Science.gov (United States)

    Ma, Xiaohui; Luo, Liqiang; Zhu, Limei; Yu, Liming; Sheng, Leimei; An, Kang; Ando, Yoshinori; Zhao, Xinluo

    2013-11-01

    Single-wall carbon nanotubes (SWCNTs) supported Pt-Fe nanoparticles have been prepared by one-step hydrogen arc discharge evaporation of carbon electrode containing both Pt and Fe metal elements. The formation of SWCNTs and Pt-Fe nanoparticles occur simultaneously during the evaporation process. High-temperature hydrogen treatment and hydrochloric acid soaking have been carried out to purify and activate those materials in order to obtain a new type of Pt-Fe/SWCNTs catalyst for methanol oxidation. The Pt-Fe/SWCNTs catalyst performs much higher electrocatalytic activity for methanol oxidation, better stability and better durability than a commercial Pt/C catalyst according to the electrochemical measurements, indicating that it has a great potential for applications in direct methanol fuel cells.

  10. Immediate and delayed loading of fixed dental prostheses supported by single or two splinted implants: A histomorphometric study in dogs.

    Science.gov (United States)

    Cesaretti, G; Lang, N P; Viganò, P; Bengazi, F; Apaza Alccayhuaman, K A; Botticelli, D

    2018-04-01

    To evaluate presumptive differences in osseointegration at implants supporting crowns that are physiologically loaded either immediately or 3 months after installation. All premolars and first molars were extracted bilaterally in six dogs. After 3 months of healing, three implants were installed on the premolar region and two in the molar region in one side of the mandible. Likewise, after another 3 months, five implants were installed in the contralateral side, and impressions were taken bilaterally. Within 48 hours, two single crowns were screwed bilaterally onto two implants in the premolar region, and two splinted crowns reproducing the shape of the first molar were screwed bilaterally onto the implants in the molar region. The mesial implants were used as no-loaded controls. Sacrifices were performed after 3 months, and histological analyses were performed. At the premolar sites, mineralised bone-to-implant contact (MBIC%) was 78.0 ± 4.0% and 70.9 ± 7.9% at the delayed and immediately loaded sites, respectively. This difference was statistically significant. At the control implants, MBIC% was 61.4 ± 14.7% and 63.1 ± 13.1% at the delayed and the immediately loaded sites, respectively. At the molar sites, MBIC% was 79.2 ± 10.9% and 61.1 ± 10.3% at the delayed and immediately loaded sites, respectively. Applying a delayed loading to fixed dental prostheses supported by single or two splinted implants yielded higher proportions of bone-to-implant contact (osseointegration) compared to immediately loaded implants. Moreover, both types of loading protocols yielded a higher rate of osseointegration compared to unloaded implant sites after 3 months following implant installation. © 2018 John Wiley & Sons Ltd.

  11. Screening single-atom catalysts for methane activation: α -A l2O3(0001 ) -supported Ni

    Science.gov (United States)

    Gao, Fei; Gao, Shiwu; Meng, Sheng

    2017-08-01

    Methane activation is one of the biggest challenges for chemical conversion of hydrocarbons and fundamental science. We systematically screen d -block transition metal elements as potential candidates of single-atom catalysts (SACs) for methane dissociation. The adsorption of methane on free metal atoms strongly depends on the number of d electrons of SAC, where the maximum binding energy is formed with the Ni group (electronic configuration d8s2 or d9s1 ). Interestingly, the magnetic moment of the SACs decreases by 2 μB for strong interactions, suggesting that the methane-metal bond forms a spin singlet state involving two electrons of opposite spins. To examine the effect of substrates, the screened transition metals, Ni, Rh, and Pt are further put onto prototype metal oxide surfaces. The substrate dramatically modifies the discrete energy levels of a single metal and its catalytic properties. Single Ni atoms supported on an O-terminated α -A l2O3(0001 ) surface (N i1/A l2O3 ) show superior catalytic properties, with a low activation barrier of 0.4 eV (0.11 eV after zero-point energy correction) for the C-H bond dissociation and simultaneously an extreme stability with a high binding energy of ˜9.39 eV for the Ni anchor. This work identifies N i1/A l2O3 catalyst as an optimal SAC and offers new atomistic insights into the mechanism of methane activation on SACs.

  12. Structured oligonucleotides for target indexing to allow single-vessel PCR amplification and solid support microarray hybridization.

    Science.gov (United States)

    Girard, Laurie D; Boissinot, Karel; Peytavi, Régis; Boissinot, Maurice; Bergeron, Michel G

    2015-02-07

    The combination of molecular diagnostic technologies is increasingly used to overcome limitations on sensitivity, specificity or multiplexing capabilities, and provide efficient lab-on-chip devices. Two such techniques, PCR amplification and microarray hybridization are used serially to take advantage of the high sensitivity and specificity of the former combined with high multiplexing capacities of the latter. These methods are usually performed in different buffers and reaction chambers. However, these elaborate methods have high complexity and cost related to reagent requirements, liquid storage and the number of reaction chambers to integrate into automated devices. Furthermore, microarray hybridizations have a sequence dependent efficiency not always predictable. In this work, we have developed the concept of a structured oligonucleotide probe which is activated by cleavage from polymerase exonuclease activity. This technology is called SCISSOHR for Structured Cleavage Induced Single-Stranded Oligonucleotide Hybridization Reaction. The SCISSOHR probes enable indexing the target sequence to a tag sequence. The SCISSOHR technology also allows the combination of nucleic acid amplification and microarray hybridization in a single vessel in presence of the PCR buffer only. The SCISSOHR technology uses an amplification probe that is irreversibly modified in presence of the target, releasing a single-stranded DNA tag for microarray hybridization. Each tag is composed of a 3-nucleotide sequence-dependent segment and a unique "target sequence-independent" 14-nucleotide segment allowing for optimal hybridization with minimal cross-hybridization. We evaluated the performance of five (5) PCR buffers to support microarray hybridization, compared to a conventional hybridization buffer. Finally, as a proof of concept, we developed a multiplexed assay for the amplification, detection, and identification of three (3) DNA targets. This new technology will facilitate the design

  13. Single-Trial Classification of Bistable Perception by Integrating Empirical Mode Decomposition, Clustering, and Support Vector Machine

    Directory of Open Access Journals (Sweden)

    Hualou Liang

    2008-04-01

    Full Text Available We propose an empirical mode decomposition (EMD- based method to extract features from the multichannel recordings of local field potential (LFP, collected from the middle temporal (MT visual cortex in a macaque monkey, for decoding its bistable structure-from-motion (SFM perception. The feature extraction approach consists of three stages. First, we employ EMD to decompose nonstationary single-trial time series into narrowband components called intrinsic mode functions (IMFs with time scales dependent on the data. Second, we adopt unsupervised K-means clustering to group the IMFs and residues into several clusters across all trials and channels. Third, we use the supervised common spatial patterns (CSP approach to design spatial filters for the clustered spatiotemporal signals. We exploit the support vector machine (SVM classifier on the extracted features to decode the reported perception on a single-trial basis. We demonstrate that the CSP feature of the cluster in the gamma frequency band outperforms the features in other frequency bands and leads to the best decoding performance. We also show that the EMD-based feature extraction can be useful for evoked potential estimation. Our proposed feature extraction approach may have potential for many applications involving nonstationary multivariable time series such as brain-computer interfaces (BCI.

  14. Molecular analysis of the freshwater prawn Macrobrachium olfersii (Decapoda, Palaemonidae) supports the existence of a single species throughout its distribution.

    Science.gov (United States)

    Rossi, Natália; Mantelatto, Fernando Luis

    2013-01-01

    Macrobrachium olfersii is an amphidromous freshwater prawn, widespread along the eastern coasts of the Americas. This species shows great morphological modifications during ontogenesis, and several studies have verified the existence of a wide intraspecific variation. Because of this condition, the species is often misidentified, and several synonyms have been documented. To elucidate these aspects, individuals of M. olfersii from different populations along its range of distribution were investigated. The taxonomic limit was established, and the degree of genetic variability of this species was described. We extracted DNA from 53 specimens of M. olfersii, M. americanum, M. digueti and M. faustinum, which resulted in 84 new sequences (22 of 16S mtDNA, 45 of Cythocrome Oxidase I (COI) mtDNA, and 17 of Histone (H3) nDNA). Sequences of three genes (single and concatenated) from these species were used in the Maximum Likelihood and Bayesian Inference phylogenetic analyses and COI sequences from M. olfersii were used in population analysis. The genetic variation was evaluated through the alignment of 554 bp from the 16S, 638 bp from the COI, and 338 bp from the H3. The rates of genetic divergence among populations were lower at the intraspecific level. This was confirmed by the haplotype net, which showed a continuous gene flow among populations. Although a wide distribution and high morphological intraspecific variation often suggest the existence of more than one species, genetic similarity of Caribbean and Brazilian populations of M. olfersii supported them as a single species.

  15. Molecular analysis of the freshwater prawn Macrobrachium olfersii (Decapoda, Palaemonidae supports the existence of a single species throughout its distribution.

    Directory of Open Access Journals (Sweden)

    Natália Rossi

    Full Text Available Macrobrachium olfersii is an amphidromous freshwater prawn, widespread along the eastern coasts of the Americas. This species shows great morphological modifications during ontogenesis, and several studies have verified the existence of a wide intraspecific variation. Because of this condition, the species is often misidentified, and several synonyms have been documented. To elucidate these aspects, individuals of M. olfersii from different populations along its range of distribution were investigated. The taxonomic limit was established, and the degree of genetic variability of this species was described. We extracted DNA from 53 specimens of M. olfersii, M. americanum, M. digueti and M. faustinum, which resulted in 84 new sequences (22 of 16S mtDNA, 45 of Cythocrome Oxidase I (COI mtDNA, and 17 of Histone (H3 nDNA. Sequences of three genes (single and concatenated from these species were used in the Maximum Likelihood and Bayesian Inference phylogenetic analyses and COI sequences from M. olfersii were used in population analysis. The genetic variation was evaluated through the alignment of 554 bp from the 16S, 638 bp from the COI, and 338 bp from the H3. The rates of genetic divergence among populations were lower at the intraspecific level. This was confirmed by the haplotype net, which showed a continuous gene flow among populations. Although a wide distribution and high morphological intraspecific variation often suggest the existence of more than one species, genetic similarity of Caribbean and Brazilian populations of M. olfersii supported them as a single species.

  16. Support effects in single atom iron catalysts on adsorption characteristics of toxic gases (NO2, NH3, SO3 and H2S)

    Science.gov (United States)

    Gao, Zhengyang; Yang, Weijie; Ding, Xunlei; Lv, Gang; Yan, Weiping

    2018-04-01

    The effects of support on gas adsorption is crucial for single atom catalysts design and optimization. To gain insight into support effects on gas adsorption characteristics, a comprehensive theoretical study was performed to investigate the adsorption characteristics of toxic gases (NO2, NH3, SO3 and H2S) by utilizing single atom iron catalysts with three graphene-based supports. The adsorption geometry, adsorption energy, electronic and magnetic properties of the adsorption system have been explored. Additionally, the support effects have been analyzed through d-band center and Fermi softness, and thermodynamic analysis has been performed to consider the effect of temperature on gas adsorption. The support effects have a remarkable influence on the adsorption characteristics of four types of toxic gases which is determined by the electronic structure of graphene-based support, and the electronic structure can be characterized by Fermi softness of catalysts. Fermi softness and uplift height of Fe atom could be good descriptors for the adsorption activity of single atom iron catalysts with graphene-based supports. The findings can lay a foundation for the further study of graphene-based support effects in single atom catalysts and provide a guideline for development and design of new graphene-based support materials utilizing the idea of Fermi softness.

  17. Evaluation of zirconia-based posterior single crowns supported by zirconia implants: preliminary results of a prospective multicenter study.

    Science.gov (United States)

    Spies, Benedikt Christopher; Kohal, Ralf-Joachim; Balmer, Marc; Vach, Kirstin; Jung, Ronald E

    2017-05-01

    The aim of this uncontrolled prospective multicenter study was to determine the success and survival rate of posterior single crowns composed of zirconia frameworks hand-layered with a leucite-reinforced feldspathic ceramic supported by one-piece zirconia oral implants. In two centers, sixty patients received 71 zirconia oral implants. To obtain a clear indication of posterior implant-supported single crowns (ISSCs), 14 patients (25 implants) were excluded from the analysis (11 bridges, three anterior crowns). The remaining patients were provided with single implants in posterior regions. As one patient lost his implant and another refused further participation after final prosthesis insertion, 44 ISSCs/patients (19 females, 25 males) were available for evaluation. Of these patients, all were seen at prosthetic delivery and the 6- and 12-month follow-up appointments. Evaluations were performed using modified United States Public Health Service (USPHS) criteria. Restorations within Alpha and Bravo ratings were regarded as success. This included minor chippings, a slight roughness, slightly soundable restoration margins and minimal contour deficiencies. In case of more distinct defects that could, however, be repaired to a clinically acceptable level, restorations were regarded as surviving. Kaplan-Meier plots and log-rank tests were used for the success/survival analyses and the calculation of potential group differences (gender, jaw and center). After a mean observation period of 12.5 months (SD: 0.8 months), no ISSC had to be replaced, resulting in a Kaplan-Meier survival rate of 100%. The Kaplan-Meier success rate was 90.9% (one major chipping, one obvious roughness, one significant crevice and one pronounced over-contouring). Minor chippings and occlusal roughness were frequent complications. No significantly different survival/success rates could be observed between the mentioned groups. The frequent incidence of minor chippings suggests a high technique

  18. Clinical performance of screw-retained and cemented implant-supported zirconia single crowns: 36-month results.

    Science.gov (United States)

    Cacaci, Claudio; Cantner, Friederike; Mücke, Thomas; Randelzhofer, Peter; Hajtó, Jan; Beuer, Florian

    2017-07-01

    The objective of this clinical study was to evaluate the clinical performance of implant-supported zirconia crowns with a sintered veneering cap. Furthermore, the influence of the type of retention (screw-retained vs cemented single crowns) was analysed. Fifty-eight patients were accommodated with 114 implants, inserted in the molar and premolar regions. Zirconia-based crowns with a sintered veneering cap were either screw-retained (n = 53) or cemented (n = 61) on the implant. Recalls were performed every 6 months. The state of soft tissue was documented by the modified plaque and gingiva index (mPI) and sulcus bleeding index (mSBI). The restorations were evaluated for technical failures like veneering porcelain fractures, surface qualities and marginal fitting. Neither implant loss nor crown fractures occurred. After a mean clinical service time of 36.9 months, fractures of the veneering porcelain were registered in 1.8 % of the cases. The Kaplan-Meier survival probability regarding eventless restorations was 98.2 %. Chipping of the veneering porcelain was registered in two cemented crowns without statistical influence of the type of retention. The indices showed healthy soft periimplant tissues in both groups. Implant-supported zirconia crowns with a sintered veneering cap demonstrated good clinical performance. The type of retention had no influence on technical complications.

  19. Management of Pediatric Acute Liver Failure in a Region With Insufficient Deceased Donor Support: A Single-Center Experience.

    Science.gov (United States)

    Yankol, Yucel; Ertugrul, Mustafa; Kanmaz, Turan; Mecit, Nesimi; Ocak, Ilhan; Durmaz, Ozlem; Acarli, Koray; Kalayoglu, Munci

    2016-10-01

    Acute liver failure is a rapidly progressive and life-threatening disease in children, whose clinical features differ from those of adults. This is a review of a single center's experience with pediatric acute liver failure in a region with insufficient deceased donor support. The study is a retrospective review and analysis of 22 pediatric patients with acute liver failure between January 2007 and May 2013. The cause of acute liver failure was indeterminate in 45.4% of cases. Listing for liver transplant was required in 72.7% of patients, whereas 27.3% developed spontaneous remission. In the patients placed on the liver transplant wait list, 75% underwent liver transplant and 25% died before undergoing liver transplant. The presence of ascites, high-grade encephalopathy, and laboratory findings including high lactate dehydrogenase and phosphorous levels and international normalized ratio were significant parameters in selecting patients needing liver transplants. All liver transplants were from living donors. One- and 3-year patient survival rates after liver transplant were 75% and 75%. No serious donor complications occurred. Living-donor liver transplant may be the only option to save the lives of pediatric patients with acute liver failure, especially in regions with insufficient deceased-donor support. Timely referral to a multidisciplinary transplant center, expedient evaluation of living donors, and appropriate timing of transplant are crucial for a successful outcome.

  20. The role of auditory feedback in music-supported stroke rehabilitation: A single-blinded randomised controlled intervention.

    Science.gov (United States)

    van Vugt, F T; Kafczyk, T; Kuhn, W; Rollnik, J D; Tillmann, B; Altenmüller, E

    2016-01-01

    Learning to play musical instruments such as piano was previously shown to benefit post-stroke motor rehabilitation. Previous work hypothesised that the mechanism of this rehabilitation is that patients use auditory feedback to correct their movements and therefore show motor learning. We tested this hypothesis by manipulating the auditory feedback timing in a way that should disrupt such error-based learning. We contrasted a patient group undergoing music-supported therapy on a piano that emits sounds immediately (as in previous studies) with a group whose sounds are presented after a jittered delay. The delay was not noticeable to patients. Thirty-four patients in early stroke rehabilitation with moderate motor impairment and no previous musical background learned to play the piano using simple finger exercises and familiar children's songs. Rehabilitation outcome was not impaired in the jitter group relative to the normal group. Conversely, some clinical tests suggests the jitter group outperformed the normal group. Auditory feedback-based motor learning is not the beneficial mechanism of music-supported therapy. Immediate auditory feedback therapy may be suboptimal. Jittered delay may increase efficacy of the proposed therapy and allow patients to fully benefit from motivational factors of music training. Our study shows a novel way to test hypotheses concerning music training in a single-blinded way, which is an important improvement over existing unblinded tests of music interventions.

  1. Lipid diffusion in the distal and proximal leaflets of supported lipid bilayer membranes studied by single particle tracking

    Science.gov (United States)

    Schoch, Rafael L.; Barel, Itay; Brown, Frank L. H.; Haran, Gilad

    2018-03-01

    Supported lipid bilayers (SLBs) have been studied extensively as simple but powerful models for cellular membranes. Yet, potential differences in the dynamics of the two leaflets of a SLB remain poorly understood. Here, using single particle tracking, we obtain a detailed picture of bilayer dynamics. We observe two clearly separate diffusing populations, fast and slow, that we associate with motion in the distal and proximal leaflets of the SLB, respectively, based on fluorescence quenching experiments. We estimate diffusion coefficients using standard techniques as well as a new method based on the blur of images due to motion. Fitting the observed diffusion coefficients to a two-leaflet membrane hydrodynamic model allows for the simultaneous determination of the intermonolayer friction coefficient and the substrate-membrane friction coefficient, without any prior assumptions on the strengths of the relevant interactions. Remarkably, our calculations suggest that the viscosity of the interfacial water confined between the membrane and the substrate is elevated by ˜104 as compared to bulk water. Using hidden Markov model analysis, we then obtain insight into the transbilayer movement of lipids. We find that lipid flip-flop dynamics are very fast, with half times in the range of seconds. Importantly, we find little evidence for membrane defect mediated lipid flip-flop for SLBs at temperatures well above the solid-to-liquid transition, though defects seem to be involved when the SLBs are cooled down. Our work thus shows that the combination of single particle tracking and advanced hydrodynamic modeling provides a powerful means to obtain insight into membrane dynamics.

  2. Can an app supporting psoriasis patients improve adherence to topical treatment? A single-blind randomized controlled trial.

    Science.gov (United States)

    Svendsen, Mathias Tiedemann; Andersen, Flemming; Andersen, Kirsten Hammond; Andersen, Klaus Ejner

    2018-02-07

    Topical corticosteroid or corticosteroid/calcipotriol preparations are recommended first-line topical treatments of psoriasis, but a main cause for the lack of efficacy of topical treatments is considered low rates of adherence to topical drugs. Patient support by the use of applications (apps) for smartphones is suggested to improve medical adherence. Design: An investigator-initiated, single-center, single-blind, parallel-group, phase-4 clinical superiority randomized controlled trial (RCT). 134 patients 18 to 75 years of age with mild-to-moderate psoriasis, who are capable of reading English language, own a smartphone, and are candidates for the study drug calcipotriol and betamethasone dipropionate (Cal/BD) cutaneous foam once daily prn (pro re nata). A 28-day adherence-supporting app providing compulsory daily treatment reminders that pop-up on the smartphone screen with a short alert sound. The app synchronizes through Bluetooth® to an electronic monitor (EM) attached to the medication canister. The EM contains a chip registering the amount of foam, day and time the patient use the foam dispenser. The information is displayed in a diary that shows the amount of Cal/BD cutaneous foam used and the number of applied treatment sessions. The app has an optional diary with the patient's rating of symptoms. Non-intervention: Use of Cal/BD cutaneous foam and EM without the app. All participants are prescribed Cal/BD cutaneous foam prn for the entire study period. Primary outcome obtained in week 4: rates of adherence measured by patient report, weight of medication canisters, and number of treatment sessions measured by the EM. Secondary outcomes obtained at baseline, weeks 4, 8, and 26: Lattice System Physician's Global Assessment (LS-PGA) and Dermatology Quality of Life Index (DLQI). This trial tests of whether an app can improve rates of adherence to a topical antipsoriatic drug. If the app improves rates of adherence and reduces the burden of psoriasis in a

  3. A 1-year randomised controlled trial comparing zirconia versus metal-ceramic implant supported single-tooth restorations.

    Science.gov (United States)

    Hosseini, Mandana; Worsaae, Nils; Schiodt, Morten; Gotfredsen, Klaus

    2011-01-01

    To compare the biological, technical and aesthetic outcomes of single implant-supported all-ceramic versus metal-ceramic crowns. Thirty-six patients with premolar agenesis were randomly treated with 38 all-ceramic (AC) and 37 metal-ceramic (MC) implant-supported single-tooth restorations. A quasi-randomisation of consecutively included restorations in patients with one or more implants was used, i.e. a combination of parallel group (for 13 patients with one restoration) and split-mouth (for 23 patients with ≥2 restorations). All patients were recalled for baseline and 1-year followup examinations. Biological and technical outcomes, including complications, were clinically and radiographically registered. The Copenhagen Index Score and visual analogue scale (VAS) score were used to assess professional and patient-reported aesthetic outcomes, respectively, by blinded assessors. One-year after loading, no patient dropped out and no implant failed, though one MC restoration had to be remade. The marginal bone loss was not significantly different between AC and MC restorations (AC: mean 0.08 mm, SD 0.25; MC: mean 0.10 mm, SD 0.17). Seven out of 10 inflammatory reactions were registered at AC restorations. Two technical complications, one loss of retention and one chipping of veneering porcelain were recorded at two metal-ceramic crowns. The marginal adaptation of the all-ceramic crowns was significantly less optimal than the metal-ceramic crowns (P = 0.014). The professional-reported colour match of all-ceramic crowns was significantly better than metal-ceramic crowns (P = 0.031), but other aesthetic parameters as well as the VAS scores demonstrated no statistically significant difference between AC and MC restorations. Marginal bone loss and the aesthetic outcomes were not significantly different between AC and MC restorations in this short-term follow-up study, though inflammatory reactions in the peri-implant mucosa as well as less optimal marginal adaptation were

  4. A Forest of Sub-1.5-nm-wide Single-Walled Carbon Nanotubes over an Engineered Alumina Support

    Science.gov (United States)

    Yang, Ning; Li, Meng; Patscheider, Jörg; Youn, Seul Ki; Park, Hyung Gyu

    2017-04-01

    A precise control of the dimension of carbon nanotubes (CNTs) in their vertical array could enable many promising applications in various fields. Here, we demonstrate the growth of vertically aligned, single-walled CNTs (VA-SWCNTs) with diameters in the sub-1.5-nm range (0.98 ± 0.24 nm), by engineering a catalyst support layer of alumina via thermal annealing followed by ion beam treatment. We find out that the ion beam bombardment on the alumina allows the growth of ultra-narrow nanotubes, whereas the thermal annealing promotes the vertical alignment at the expense of enlarged diameters; in an optimal combination, these two effects can cooperate to produce the ultra-narrow VA-SWCNTs. According to micro- and spectroscopic characterizations, ion beam bombardment amorphizes the alumina surface to increase the porosity, defects, and oxygen-laden functional groups on it to inhibit Ostwald ripening of catalytic Fe nanoparticles effectively, while thermal annealing can densify bulk alumina to prevent subsurface diffusion of the catalyst particles. Our findings contribute to the current efforts of precise diameter control of VA-SWCNTs, essential for applications such as membranes and energy storage devices.

  5. Mitochondrial population genomics supports a single pre-Clovis origin with a coastal route for the peopling of the Americas.

    Science.gov (United States)

    Fagundes, Nelson J R; Kanitz, Ricardo; Eckert, Roberta; Valls, Ana C S; Bogo, Mauricio R; Salzano, Francisco M; Smith, David Glenn; Silva, Wilson A; Zago, Marco A; Ribeiro-dos-Santos, Andrea K; Santos, Sidney E B; Petzl-Erler, Maria Luiza; Bonatto, Sandro L

    2008-03-01

    It is well accepted that the Americas were the last continents reached by modern humans, most likely through Beringia. However, the precise time and mode of the colonization of the New World remain hotly disputed issues. Native American populations exhibit almost exclusively five mitochondrial DNA (mtDNA) haplogroups (A-D and X). Haplogroups A-D are also frequent in Asia, suggesting a northeastern Asian origin of these lineages. However, the differential pattern of distribution and frequency of haplogroup X led some to suggest that it may represent an independent migration to the Americas. Here we show, by using 86 complete mitochondrial genomes, that all Native American haplogroups, including haplogroup X, were part of a single founding population, thereby refuting multiple-migration models. A detailed demographic history of the mtDNA sequences estimated with a Bayesian coalescent method indicates a complex model for the peopling of the Americas, in which the initial differentiation from Asian populations ended with a moderate bottleneck in Beringia during the last glacial maximum (LGM), around approximately 23,000 to approximately 19,000 years ago. Toward the end of the LGM, a strong population expansion started approximately 18,000 and finished approximately 15,000 years ago. These results support a pre-Clovis occupation of the New World, suggesting a rapid settlement of the continent along a Pacific coastal route.

  6. Evaluation of the single-pass flow-through test to support a low-activity waste specification

    International Nuclear Information System (INIS)

    McGrail, B.P.; Peeler, D.K.

    1995-09-01

    A series of single-pass flow-through (SPFT) tests was performed on five reference low-activity waste glasses and a reference glass from the National Institute of Standards and Technology to support a product specification for low-activity waste (LAW) forms. The results showed that the SPFT test provides a means to quantitatively distinguish among LAW glass forms in terms of their forward reaction rate at a given temperature and solution pH. Two of the test glasses were also subjected to SPFT testing at Argonne National Laboratory (ANL). Forward reaction rate constants calculated from the ANL test data were 100 to over 1,000 times larger than the values obtained from the SPFT tests conducted at PNL. An analysis of the ANL results showed that they were inconsistent with independent measurements done on glasses of similar composition, the known pH-dependence of the forward rate, and with the results from low surface-area-to-volume, short duration product consistency tests. Because the data set obtained from the SPFT tests done at PNL was consistent with each of these same factors, a detailed examination of the test procedures used at both laboratories was performed to determine the cause(s) of the discrepancy. The omission of background subtraction in the data analysis procedure and the short-duration (on the order of hours) of the ANL tests are factors that may have significantly affected the calculated rates

  7. Single Mothers by Choice and Inwedlock Mothers: Sex-Role Orientation, Locus of Control, and Social Support.

    Science.gov (United States)

    Holle, Kimberly Ann

    An emerging family constellation is the family headed by a "single mother by choice," a structure in which both single marital status and parental status are chosen. This study was conducted to determine whether single mothers by choice (N=12) differed significantly from inwedlock mothers (N=18) regarding their childbearing decisions.…

  8. Comparison of implant versus tooth-supported zirconia-based single crowns in a split-mouth design: a 4-year clinical follow-up study.

    Science.gov (United States)

    Güncü, Mustafa Barış; Cakan, Umut; Aktas, Guliz; Güncü, Güliz Nigar; Canay, Şenay

    2016-12-01

    This study aims to evaluate the 4-year clinical performance of tooth versus implant-supported single-unit zirconia crowns (LAVA™) placed on posterior region. Twenty-four patients (10 men and 14 women) who had received 48 single crowns (24 implant-supported and 24 tooth-supported) from January 2007 to December 2009, were included. California Dental Association (CDA) quality assessment system, plaque and gingival index scores were used to evaluate the performance of the crowns at baseline and at all follow-up examinations. During the follow-up period, no fracture of zirconia coping has occurred. Major complication was chipping in three patients that required a new crown fabrication. Except for the failure ones, all crowns in both groups were rated as satisfactory at the follow-up examinations based on the CDA quality assessment criteria. There were no statistically significant differences between tooth and implant-supported crowns in terms of periodontal parameters. The present 4-year follow-up clinical study demonstrates that single-unit tooth- and implant-supported zirconia crowns have similar prosthetic and periodontal outcomes. Single-unit implant or tooth-supported zirconia crowns may be considered acceptable treatment modalities for restoration of either missing or compromised posterior teeth.

  9. Examining the rudimentary steps of the oxygen reduction reaction on single-atomic Pt using Ti-based non-oxide supports

    DEFF Research Database (Denmark)

    Tak, Young Joo; Yang, Sungeun; Lee, Hyunjoo

    2018-01-01

    In the attempt to reduce the high-cost and improve the overall durability of Pt-based electrocatalysts for the oxygen reduction reaction (ORR), density-functional theory (DFT) calculations have been performed to study the energetics of the elementary steps that occur during ORR on TiN(100)- and T...... of the single-atom Pt catalyst, and directly influences the rudimentary ORR steps on these single-atom platinized supports....

  10. Analysis of the distribution of stress and deformation in single implant-supported prosthetic units in implants of different diameters

    Directory of Open Access Journals (Sweden)

    Francesco Salvatore MANNARINO

    Full Text Available Abstract Introduction When stress and strain levels in the bone-implant system exceed It's capacity, a mechanical fatigue occurs, resulting in collapse and loss of osseointegration. Objective Analyze biomechanical behavior in single implant-supported prosthesis with implants of different diameters in the posterior mandible. Material and method Three different finite element models of Cone-Morse implants with the same height were created, varying the diameter (3.3 mm, 4.1 mm and 4.8 mm. The mandibular first molar area was the location of the implant, with It´s component and overlying prosthetic crown. The jawbone was composed of cortical and cancellous bone. Refined mesh of 0.5 mm was created in the critical interfaces to be analyzed. The loading of the models was performed at the point of occlusal contact with an occlusal load of 400 N. Result Maximum stress and strain occurred in the cervical regions of the implants in all groups, either in the implants or in components as well as in the analysis of cortical bone. The greater the diameter, the lower the stress and strain found in the implant. The 3.3 mm group had the highest strain in peri-implant cortical bone, and the 4.1 mm group had the smallest deformation, significantly lower than in the 4.8 mm group. Conclusion Although the biggest implant diameter (4.8 mm appears to have lower values of stress and strain, the group of intermediate implant diameter (4.1 mm showed less deformation rate in the cortical peri-implant bone. Therefore it is concluded that the 4.1 mm implant platform presented a more biomechanically effective peri-implant bone maintenance.

  11. Evaluation of aesthetics of implant-supported single-tooth replacements using different bone augmentation procedures : A prospective randomized clinical study

    NARCIS (Netherlands)

    Meijndert, Leo; Meijer, Henny J. A.; Stellingsma, Kees; Stegenga, Boudewijn; Raghoebar, Gerry M.

    2007-01-01

    Objectives: The aim of this study was to evaluate the aesthetics of implant-supported single-tooth replacements using different augmentation procedures in a prospective study with the use of an objective rating index and with a subjective patient questionnaire, and to compare the results with each

  12. Long-term outcomes of short dental implants supporting single crowns in posterior region: a clinical retrospective study of 5-10 years

    NARCIS (Netherlands)

    Lai, H.C.; Si, M.S.; Zhuang, L.F.; Shen, H.; Liu, Y.; Wismeijer, D.

    2013-01-01

    OBJECTIVE: Aimed to evaluate the long-term clinical and radiographic outcomes of short implants supporting single crowns in the posterior regions. MATERIAL AND METHODS: A retrospective study design was adopted. The clinical and radiographic data of 231 short implants (intra-bony length ≤8 mm)

  13. The role of prosthetic abutment material on the stress distribution in a maxillary single implant-supported fixed prosthesis

    Energy Technology Data Exchange (ETDEWEB)

    Peixoto, Hugo Eduardo, E-mail: hugo.e.peixoto@hotmail.com [Implantology Team, Latin American Institute of Research and Education in Dentistry, Curitiba, Paraná (Brazil); Bordin, Dimorvan, E-mail: dimorvan_bordin@hotmail.com [Department of Prosthodontics and Periodontology, Piracicaba Dental School, State University of Campinas, Limeira avenue, 901-Vila Rezende, Piracicaba, SP 13414-903 (Brazil); Del Bel Cury, Altair A., E-mail: altcury@fop.unicamp.br [Department of Prosthodontics and Periodontology, Piracicaba Dental School, State University of Campinas, Limeira avenue, 901-Vila Rezende, Piracicaba, SP 13414-903 (Brazil); Silva, Wander José da, E-mail: wanderjose@fop.unicamp.br [Department of Prosthodontics and Periodontology, Piracicaba Dental School, State University of Campinas, Limeira avenue, 901-Vila Rezende, Piracicaba, SP 13414-903 (Brazil); Faot, Fernanda, E-mail: fernanda.faot@gmail.com [Department of Restorative Dentistry, School of Dentistry, Federal University of Pelotas, Gonçalves Chaves, 457, 2nd floor, Pelotas, Rio Grande do Sul 96015-560 (Brazil)

    2016-08-01

    Purpose: Evaluate the influence of abutment's material and geometry on stress distribution in a single implant-supported prosthesis. Materials and Methods: Three-dimensional models were made based on tomographic slices of the upper middle incisor area, in which a morse taper implant was positioned and a titanium (Ti) or zirconia (ZrN) universal abutments was installed. The commercially available geometry of titanium (T) and zirconia (Z) abutments were used to draw two models, TM1 and ZM1 respectively, which served as control groups. These models were compared with 2 experimental groups were the mechanical properties of Z were applied to the titanium abutment (TM2) and vice versa for the zirconia abutment (ZM2). Subsequently, loading was simulated in two steps, starting with a preload phase, calculated with the respective friction coefficients of each materials, followed by a combined preload and chewing force. The maximum von Mises stress was described. Data were analyzed by two-way ANOVA that considered material composition, geometry and loading (p < 0.05). Results: Titanium and zirconia abutments showed similar von Mises stresses in the mechanical part of the four models. The area with the highest concentration of stress was the screw thread, following by the screw body. The highest stress levels occurred in screw thread was observed during the preloading phase in the ZM1 model (931 MPa); and during the combined loading in the TM1 model (965 MPa). Statistically significant differences were observed for loading, the material × loading interaction, and the loading × geometry interaction (p < 0.05). Preloading contributed for 77.89% of the stress (p < 0.05). There were no statistically significant differences to the other factors (p > 0.05). Conclusion: The screw was the piece most intensely affected, mainly through the preload force, independent of the abutment's material. - Highlights: • The abutment's screw was the most impaired piece of the

  14. Home detection of freezing of gait using support vector machines through a single waist-worn triaxial accelerometer

    Science.gov (United States)

    Pérez-López, Carlos; Català, Andreu; Moreno Arostegui, Joan M.; Cabestany, Joan; Bayés, Àngels; Alcaine, Sheila; Mestre, Berta; Prats, Anna; Crespo, M. Cruz; Counihan, Timothy J.; Browne, Patrick; Quinlan, Leo R.; ÓLaighin, Gearóid; Sweeney, Dean; Lewy, Hadas; Azuri, Joseph; Vainstein, Gabriel; Annicchiarico, Roberta; Costa, Alberto; Rodríguez-Molinero, Alejandro

    2017-01-01

    Among Parkinson’s disease (PD) symptoms, freezing of gait (FoG) is one of the most debilitating. To assess FoG, current clinical practice mostly employs repeated evaluations over weeks and months based on questionnaires, which may not accurately map the severity of this symptom. The use of a non-invasive system to monitor the activities of daily living (ADL) and the PD symptoms experienced by patients throughout the day could provide a more accurate and objective evaluation of FoG in order to better understand the evolution of the disease and allow for a more informed decision-making process in making adjustments to the patient’s treatment plan. This paper presents a new algorithm to detect FoG with a machine learning approach based on Support Vector Machines (SVM) and a single tri-axial accelerometer worn at the waist. The method is evaluated through the acceleration signals in an outpatient setting gathered from 21 PD patients at their home and evaluated under two different conditions: first, a generic model is tested by using a leave-one-out approach and, second, a personalised model that also uses part of the dataset from each patient. Results show a significant improvement in the accuracy of the personalised model compared to the generic model, showing enhancement in the specificity and sensitivity geometric mean (GM) of 7.2%. Furthermore, the SVM approach adopted has been compared to the most comprehensive FoG detection method currently in use (referred to as MBFA in this paper). Results of our novel generic method provide an enhancement of 11.2% in the GM compared to the MBFA generic model and, in the case of the personalised model, a 10% of improvement with respect to the MBFA personalised model. Thus, our results show that a machine learning approach can be used to monitor FoG during the daily life of PD patients and, furthermore, personalised models for FoG detection can be used to improve monitoring accuracy. PMID:28199357

  15. The effect of defects on the catalytic activity of single Au atom supported carbon nanotubes and reaction mechanism for CO oxidation.

    Science.gov (United States)

    Ali, Sajjad; Fu Liu, Tian; Lian, Zan; Li, Bo; Sheng Su, Dang

    2017-08-23

    The mechanism of CO oxidation by O 2 on a single Au atom supported on pristine, mono atom vacancy (m), di atom vacancy (di) and the Stone Wales defect (SW) on single walled carbon nanotube (SWCNT) surface is systematically investigated theoretically using density functional theory. We determine that single Au atoms can be trapped effectively by the defects on SWCNTs. The defects on SWCNTs can enhance both the binding strength and catalytic activity of the supported single Au atom. Fundamental aspects such as adsorption energy and charge transfer are elucidated to analyze the adsorption properties of CO and O 2 and co-adsorption of CO and O 2 molecules. It is found that CO binds stronger than O 2 on Au supported SWCNT. We clearly demonstrate that the defected SWCNT surface promotes electron transfer from the supported single Au atom to O 2 molecules. On the other hand, this effect is weaker for pristine SWCNTs. It is observed that the high density of spin-polarized states are localized in the region of the Fermi level due to the strong interactions between Au (5d orbital) and the adjacent carbon (2p orbital) atoms, which influence the catalytic performance. In addition, we elucidate both the Langmuir-Hinshelwood (LH) and Eley-Rideal (ER) mechanisms of CO oxidation by O 2 . For the LH pathway, the barriers of the rate-limiting step are calculated to be 0.02 eV and 0.05 eV for Au/m-SWCNT and Au/di-SWCNT, respectively. To regenerate the active sites, an ER-like reaction occurs to form a second CO 2 molecule. The ER pathway is observed on Au/m-SWCNT, Au/SW-SWCNT and Au/SWCNT in which the Au/m-SWCNT has a smaller barrier. The comparison with a previous study (Lu et al., J. Phys. Chem. C, 2009, 113, 20156-20160.) indicates that the curvature effect of SWCNTs is important for the catalytic property of the supported single Au. Overall, Au/m-SWCNT is identified as the most active catalyst for CO oxidation compared to pristine SWCNT, SW-SWCNT and di-SWCNT. Our findings give a

  16. A mixed-methods approach for analysing social support and social anchorage of single mothers’ personal networks

    NARCIS (Netherlands)

    Lumino, Rosaria; Ragozini, Giancarlo; van Duijn, Marijtje; Vitale, Maria Prosperina

    2017-01-01

    The present paper analyses the relationship among social support and personal networks by focusing on social anchorage, which is a specific dimension of social support conveying to what extent people feel integrated into their personal networks. Specifying when, why, and how personal relationships

  17. Monitoring Risk Behaviors by Managing Social Support in the Network of a Forensic Psychiatric Patient : A Single-Case Analysis

    NARCIS (Netherlands)

    ter Haar-Pomp, Lydia; de Beer, Carlijn; van der Lem, Rosalind; Spreen, Marinus; Bogaerts, Stefan

    2015-01-01

    This prospective case study examines changes over time in the social support network of a forensic psychiatric patient diagnosed with attention deficit hyperactivity disorder (ADHD). The focus is on the functional and dysfunctional influences of the patient's social support dynamics on his risk

  18. Spine buddy® supportive pad impact on single-leg static balance and a jogging gait of individuals wearing a military backpack.

    Science.gov (United States)

    Ward, John; Coats, Jesse; Pourmoghaddam, Amir

    2014-12-09

    The Spine Buddy® supportive pad was developed to be inserted underneath military backpacks to help disperse the heavy load of the backpack. The purpose of this study was to determine the impact the additional supportive pad had on static balance and a running gait while wearing a military backpack. Forty healthy subjects (age= 27.5 + 5.6 yrs, body height= 1.78 + 0.06 m, body mass= 86.5 + 14.0 kg: mean + SD) participated in a static single-leg balance test on a force plate with each lower limb while wearing a 15.9 kg military backpack for 30 s. Following this, participants were randomized to one of two interventions: 1) Intervention, which wore the Spine Buddy® supportive pad underneath their backpack or 2) Control, with no additional supportive pad. Post-intervention measurements of static single-leg balance were then recorded. Afterwards, a similar pre vs post testing schedule and randomization scheme was used to test the impact of the supportive pad on a 5 mph jogging gait using Vicon® cameras. Within-group data were analyzed with a 2-way repeated measures ANOVA. Statistically significant differences were not seen between the control and experimental group for balance and gait variables. Preliminarily, this suggests that the Spine Buddy® supportive pad causes no deleterious effect on static balance and a jogging gait in 18-45 year-old asymptomatic individuals.

  19. Spine Buddy® Supportive Pad Impact on Single-Leg Static Balance and a Jogging Gait of Individuals Wearing a Military Backpack

    Directory of Open Access Journals (Sweden)

    Ward John

    2014-12-01

    Full Text Available The Spine Buddy® supportive pad was developed to be inserted underneath military backpacks to help disperse the heavy load of the backpack. The purpose of this study was to determine the impact the additional supportive pad had on static balance and a running gait while wearing a military backpack. Forty healthy subjects (age= 27.5 + 5.6 yrs, body height= 1.78 + 0.06 m, body mass= 86.5 + 14.0 kg: mean + SD participated in a static single-leg balance test on a force plate with each lower limb while wearing a 15.9 kg military backpack for 30 s. Following this, participants were randomized to one of two interventions: 1 Intervention, which wore the Spine Buddy® supportive pad underneath their backpack or 2 Control, with no additional supportive pad. Post-intervention measurements of static single-leg balance were then recorded. Afterwards, a similar pre vs post testing schedule and randomization scheme was used to test the impact of the supportive pad on a 5 mph jogging gait using Vicon® cameras. Within-group data were analyzed with a 2-way repeated measures ANOVA. Statistically significant differences were not seen between the control and experimental group for balance and gait variables. Preliminarily, this suggests that the Spine Buddy® supportive pad causes no deleterious effect on static balance and a jogging gait in 18-45 year-old asymptomatic individuals.

  20. Influence of transmucosal height in abutments of single and multiple implant-supported prostheses: a non-linear three-dimensional finite element analysis.

    Science.gov (United States)

    Borie, Eduardo; Leal, Eduardo; Orsi, Iara Augusta; Salamanca, Carlos; Dias, Fernando José; Weber, Benjamin

    2018-01-01

    The aim of this study was to analyze the influence of three different transmucosal heights of the abutments in single and multiple implant-supported prostheses through the finite element method. External hexagon implants, MicroUnit, and EsthetiCone abutments were scanned and placed in an edentulous maxillary model obtained from a tomography database. The simulations were divided into two groups: (1) one implant with 3.75 × 10 mm placed in the upper central incisor, simulating a single implant-supported fixed prosthesis with an EsthetiCone abutment; and (2) two implants with 3.75 × 10 mm placed in the upper lateral incisors with MicroUnit abutments, simulating a multiple implant-supported prosthesis. Subsequently, each group was subdivided into three models according to the transmucosal height (1, 2, and 3 mm). A static oblique load at an angle of 45 degrees to the long axis of the implant in palatal-buccal direction of 150 and 75 N was applied for multiple and single implant-supported prosthesis, respectively. The implants and abutments were assessed according to the equivalent Von Mises stress analyses while the bone and ceramics were analyzed through maximum and minimum principal stresses. The total deformation values increased in all models, while the transmucosal height was augmented. The transmucosal height of the abutments influences the stress values at the bone, ceramics, implants, and abutments of both the single and multiple implant-supported prostheses, with the transmucosal height of 1 mm showing the lowest stress values.

  1. Investigating the effect of home care program on self-efficacy of femaleheaded single-parent households supported by Isfahan Welfare Organization (Behzisti in year 1394

    Directory of Open Access Journals (Sweden)

    Parvin Moeini

    2016-11-01

    Full Text Available Introduction: Female-headed households are among the most vulnerable groups of society and there are potential of many critical jeopardies for these families. Therefore, this study was focused to evaluate the effect of home care program on self-efficacy of female-headed single parent households supported by Isfahan Behzisti-Welfare Organization in year 2015. Methodology: This study was a quasi-experimental design research with random selection of 36 female headed single parent. Prior to the nursing intervention, demographic and life style information of these families were evaluated using 70 questions in a questionnaires. In addition, a pre-test using a standard self-efficacy questionnaires with 17 questions were used to assess the level of self-efficacy of these families. Following the experiment, these families responded to the self-efficacy questionnaires. For descriptive statistics analysis, frequency, average, and standard deviation were evaluated. Furthermore, paired-sample t-test, Pearson's chi-squared test, Mann–Whitney test, Spearman's rank-order correlation, and Kruskal–Wallis one-way analysis of variance were analyzed using SPSS v.18 software for statistical inference analysis. Results: Our analysis revealed that there was a significant difference (p<0.05 between the score average of pre- and post- home care program. It supported our hypothesis that the supportive home care program had significant effect on self-efficacy of femaleheaded single parent households. Discussion and Conclusion: Following the effect of the supportive nursing intervention on self-efficacy of female-headed households, it should be mentioned that this supportive program can be the best strategic plan to increase the family’s health and preventing health issues. Therefore, given the multiple roles of public health nurse, supportive home care program is critical and should be emphasized.

  2. An analysis of reliability and validity of the papilla index score of implant-supported single crowns of maxillary central incisors

    DEFF Research Database (Denmark)

    Peng, Min; Fei, Wei; Hosseini, Mandana

    2012-01-01

    Objectives: To test the reliability and validity of the papilla index scores of the implant-supported single crowns (ISSCs) of maxillary central incisors. Materials and Methods: Twenty-five patients with 25 ISSCs were included. Two prosthodontists evaluated the papilla index score (PIS) of three ...... inter-observer agreement. The PIS score demonstrated significant correlation to the corresponding PP value (rs=.567, p=.000). Conclusions: The feasibility, reliability and validity of the PIS made the parameter useful for quality control of the pri-implant soft tissue of ISSCs.......Objectives: To test the reliability and validity of the papilla index scores of the implant-supported single crowns (ISSCs) of maxillary central incisors. Materials and Methods: Twenty-five patients with 25 ISSCs were included. Two prosthodontists evaluated the papilla index score (PIS) of three...

  3. A 3-year prospective study of implant-supported, single-tooth restorations of all-ceramic and metal-ceramic materials in patients with tooth agenesis

    DEFF Research Database (Denmark)

    Hosseini, Mandana; Worsaae, Nils; Schiødt, Morten

    2013-01-01

    OBJECTIVES: The purpose of this clinical study was to describe outcome variables of all-ceramic and metal-ceramic implant-supported, single-tooth restorations. MATERIALS AND METHODS: A total of 59 patients (mean age: 27.9 years) with tooth agenesis and treated with 98 implant-supported single...... abutment materials. The frequency of biological complications was higher at restorations with all-ceramic restorations than metal-ceramic crowns. Loss of retention, which was only observed at metal-ceramic crowns, was the most frequent technical complication, and the marginal adaptations of all-ceramic...... restoration materials were registered. After 3 years, the patient-reported outcome variables at different restoration materials were not significantly different. CONCLUSION: The biological outcomes at the zirconia and metal abutments were comparable. All-ceramic crowns demonstrated better colour match...

  4. Comparison of masticatory efficiency, patient satisfaction for single, two, and three implants supported overdenture in the same patient: A pilot study

    Science.gov (United States)

    Bhat, Srinidhi; Chowdhary, Ramesh; Mahoorkar, Sudhindra

    2016-01-01

    Statement of Problem: Over 30% of the world population suffers from edentulism. Implant supported overdenture have been a relatively successful treatment option for edentulism and have shown to slowed the rate of residual resorption and maintain the vertical height of the residual. Purpose: The purpose of this study was to measure patient masticatary efficiency and satisfaction with the mandibular one-, two-, and three-implant-retained overdenture therapy when compared with conventional denture in a the same patients. Materials and Methods: Ten complete edentulous patients, who were wearing conventional complete dentures, were involved in this study. Three single piece endosseous implant of 3.0 mm in diameter and 13 mm in length were surgically placed in the mandible in the region of B, C, and D. Mandibular denture was connected for single, two, and three implant supported overdenture periodically and checked for masticatory efficiency using a bite gauge and patient satisfaction using a questionnaire. Results: Statistical analysis was done using Wilcoxon signed rank test. Four groups of bite forces when compared to each other. Group 1 was compared with Group 2, with the statistical value showing significance. Signed rank test showed no significance (0.268) when Group 2 was compared with Group 3. When Group 3 was compared with Group 4, and Group 1 compared with Group 4, rank test showed significant values. Four groups were compared with each other for patient satisfaction, Group 1 was compared with Group 2, with the statistical value showing no significance. Conclusions: A single midline implant supported overdenture can be considered as a suitable and cost-effective treatment option over conventional denture. The study concludes that masticatory efficiency of this single midline implant supported overdenture is better than the conventional complete denture. PMID:27141169

  5. Long-term outcomes of short dental implants supporting single crowns in posterior region: a clinical retrospective study of 5-10 years.

    Science.gov (United States)

    Lai, Hong-Chang; Si, Mi-Si; Zhuang, Long-Fei; Shen, Hui; Liu, Yue-Lian; Wismeijer, Daniel

    2013-02-01

    Aimed to evaluate the long-term clinical and radiographic outcomes of short implants supporting single crowns in the posterior regions. A retrospective study design was adopted. The clinical and radiographic data of 231 short implants (intra-bony length ≤8 mm) supporting single crowns in 168 patients, were collected after 5-10 (mean 7.22) years' follow-up. Implant and prosthesis failures, peri-implant marginal bone loss, biological and technical complications were evaluated. The influence factors on implant failure were studied. In total 4 implants and 11 prostheses failed. The 10-year (5-year) cumulative survival rate was 98.3% (98.7%) for implant-based analysis and 97.6% (98.2%) for patient-based analysis. The short implants placed in type IV bone yielded more failures than in type I-III and presented a survival rate of 94.0%. The 10-year survival rate of the prostheses was 95.2%. The mean marginal bone loss between implant installation and the 10 years' follow-up visit was 0.63 ± 0.68 mm. The marginal bone loss between the first and 5th year was minimal (0.05 ± 0.10mm and not statistically significant). 18 (7.8%) implants were exposed to biological complications, whereas 29 (12.6%) implants were involved in technical complications. High survival rates for both the implants and the prostheses could be achieved after 5-10 years for short implants supporting single crowns, without severe marginal bone loss and complications. One may conclude that a single crown supported by a short implant is a predictable treatment modality. However, short implants in type IV bone sites should be applied with caution. © 2012 John Wiley & Sons A/S.

  6. Combined single-mode/multimode fiber link supporting simplified in-building 60-GHz gigabit wireless access

    DEFF Research Database (Denmark)

    Pham, Tien Thang; Lebedev, Alexander; Beltrán, Marta

    2012-01-01

    In this paper, we propose and experimentally demonstrate a simple, cost-effective hybrid gigabit fiber-wireless system for in-building wireless access. Simplicity and cost-effectiveness are achieved in all parts of the system by utilizing direct laser modulation, optical frequency up-conversion, ......In this paper, we propose and experimentally demonstrate a simple, cost-effective hybrid gigabit fiber-wireless system for in-building wireless access. Simplicity and cost-effectiveness are achieved in all parts of the system by utilizing direct laser modulation, optical frequency up......-conversion, combined single mode/multimode fiber transmission and envelope detection. Error-free transmission of 2-Gbps data in 60-GHz band over a composite channel including 10-km standard single-mode fiber (SSMF)/1-km multimode fiber (MMF) and 6.5-m air transmission was successfully achieved....

  7. Cumulative Success Rate of Short and Ultrashort Implants Supporting Single Crowns in the Posterior Maxilla: A 3-Year Retrospective Study

    Directory of Open Access Journals (Sweden)

    Giorgio Lombardo

    2017-01-01

    Full Text Available Aim. To determine cumulative success rate (CSR of short and ultrashort implants in the posterior maxilla restored with single crowns. Patients and Methods. We performed a retrospective study in 65 patients with 139 implants. 46 were ultrashort and 93 short. Implants were placed with a staged approach and restored with single crowns. Success rate, clinical and radiographic outcomes, and crown-to-implant ratio (CIR were assessed after three years. Statistical analysis was performed by descriptive and inferential statistics. A log-binomial regression model where the main outcome was implant success was achieved. Coefficients and 95% confidence intervals were reported. Analyses were performed with Stata 13.2 for Windows. Results. 61.54% of patients were female and mean overall age was 51.9±11.08 years old. Overall CSR was 97.1% (95% CI: 92.4–98.9: 97.9 and 95.1% for short and ultrashort, respectively (P value: 0.33. Four implants failed. Covariates were not associated with CSR (P value > 0.05. Regression model showed coefficients correlated with implant success for ultrashort implants (0.87 and most of covariates but none were statistically significant (P values > 0.05. Conclusions. Our results suggest that short and ultrashort implants may be successfully placed and restored with single crowns in the resorbed maxillary molar region.

  8. Cumulative Success Rate of Short and Ultrashort Implants Supporting Single Crowns in the Posterior Maxilla: A 3-Year Retrospective Study.

    Science.gov (United States)

    Lombardo, Giorgio; Pighi, Jacopo; Marincola, Mauro; Corrocher, Giovanni; Simancas-Pallares, Miguel; Nocini, Pier Francesco

    2017-01-01

    To determine cumulative success rate (CSR) of short and ultrashort implants in the posterior maxilla restored with single crowns. We performed a retrospective study in 65 patients with 139 implants. 46 were ultrashort and 93 short. Implants were placed with a staged approach and restored with single crowns. Success rate, clinical and radiographic outcomes, and crown-to-implant ratio (CIR) were assessed after three years. Statistical analysis was performed by descriptive and inferential statistics. A log-binomial regression model where the main outcome was implant success was achieved. Coefficients and 95% confidence intervals were reported. Analyses were performed with Stata 13.2 for Windows. 61.54% of patients were female and mean overall age was 51.9 ± 11.08 years old. Overall CSR was 97.1% (95% CI: 92.4-98.9): 97.9 and 95.1% for short and ultrashort, respectively ( P value: 0.33). Four implants failed. Covariates were not associated with CSR ( P value > 0.05). Regression model showed coefficients correlated with implant success for ultrashort implants (0.87) and most of covariates but none were statistically significant ( P values > 0.05). Our results suggest that short and ultrashort implants may be successfully placed and restored with single crowns in the resorbed maxillary molar region.

  9. A feasible, aesthetic quality evaluation of implant-supported single crowns: an analysis of validity and reliability

    DEFF Research Database (Denmark)

    Hosseini, Mandana; Gotfredsen, Klaus

    2012-01-01

    OBJECTIVES: To test the reliability and validity of six aesthetic parameters and to compare the professional- and patient-reported aesthetic outcomes. MATERIAL AND METHODS: Thirty-four patients with 66 implant-supported premolar crowns were included. Two prosthodontists and 11 dental students......,24) were found between patient and professional evaluations. CONCLUSIONS: The feasibility, reliability and validity of the CIS make the parameters useful for quality control of implant-supported restorations. The professional- and patient-reported aesthetic outcomes had no significant correlation....

  10. 76 FR 78015 - Announcing the Award of a Single-Source Grant to Support Services for Haitian Medical Evacuees to...

    Science.gov (United States)

    2011-12-15

    ... support medical evacuees from the Haiti earthquake of 2010. CFDA Number: 93.576. Statutory Authority: This... affected by the earthquake in 2010. The Haitian medical evacuees were brought to the United States (U.S.) in the aftermath of the earthquake in Haiti on January 12, 2010. This is a population that arrived in...

  11. Grid Frequency Support by Single-Phase Electric Vehicles: Fast Primary Control Enhanced by a Stabilizer Algorithm

    DEFF Research Database (Denmark)

    Zecchino, Antonio; Rezkalla, Michel M.N.; Marinelli, Mattia

    2016-01-01

    ancillary services for supporting the power grid. This paper presents modeling and analysis of the benefits of primary frequency regulation by electric vehicles in a microgrid. An innovative control logic algorithm is introduced, with the purpose of curtailing the number of current set-point variations...

  12. Supported rhodium catalysts for ammonia-borane hydrolysis. Dependence of the catalytic activity on the highest occupied state of the single rhodium atoms

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Liangbing; Li, Hongliang; Zhang, Wenbo; Zhao, Xiao; Qiu, Jianxiang; Li, Aowen; Zheng, Xusheng; Zeng, Jie [Hefei National Lab. for Physical Sciences at the Microscale, Key Lab. of Strongly-Coupled Quantum Matter Physics, Chinese Academy of Sciences, Hefei, Anhui(China); Department of Chemical Physics, University of Science and Technology of China, Hefei, Anhui (China); Hu, Zhenpeng [School of Physics, Nankai University, Tianjin (China); Si, Rui [Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences (China)

    2017-04-18

    Supported metal nanocrystals have exhibited remarkable catalytic performance in hydrogen generation reactions, which is influenced and even determined by their supports. Accordingly, it is of fundamental importance to determine the direct relationship between catalytic performance and metal-support interactions. Herein, we provide a quantitative profile for exploring metal-support interactions by considering the highest occupied state in single-atom catalysts. The catalyst studied consisted of isolated Rh atoms dispersed on the surface of VO{sub 2} nanorods. It was observed that the activation energy of ammonia-borane hydrolysis changed when the substrate underwent a phase transition. Mechanistic studies indicate that the catalytic performance depended directly on the highest occupied state of the single Rh atoms, which was determined by the band structure of the substrates. Other metal catalysts, even with non-noble metals, that exhibited significant catalytic activity towards NH{sub 3}BH{sub 3} hydrolysis were rationally designed by adjusting their highest occupied states. (copyright 2017 Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim)

  13. Influence of implant position on clinical crown length and peri-implant soft tissue dimensions at implant-supported single crowns replacing maxillary central incisors

    DEFF Research Database (Denmark)

    Peng, Min; Fei, Wei; Hosseini, Mandana

    2013-01-01

    The aims of the present study were to evaluate the influence of implant position on clinical crown length and marginal soft tissue dimensions at implant-supported single crowns of maxillary central incisors, and to validate the papilla index score (PIS). Twenty-five patients, who had lost one...... as controls. Paired sample t-testand Pearson´s correlation analysis were used to analyze implant position, dimension of crownand papilla fill.Cohen’s ¿ andSpearman correlation were used to validate the PIS.The implant-supported crown was statistically longer than the contra-lateral tooth......, and there was significant correlation between the oro-facial position of the implant and the crown length difference (r=.607, p=.001). The distalpapilla was significantly shorter than the mesialpapilla at implant-supported crowns (ptooth (p=.415...

  14. Influence of group cohesion on maternal well-being among participants in a support/education group program for single mothers.

    Science.gov (United States)

    Lipman, Ellen L; Waymouth, Marjorie; Gammon, Tara; Carter, Patricia; Secord, Margaret; Leung, Olivia; Mills, Brenda; Hicks, Frances

    2007-10-01

    Single mothers are at increased risk of psychosocial disadvantage, social isolation and physical and mental health difficulties. The authors present (1) the results of group cohesion assessments completed by mothers participating in a trial of community-based support/education groups, and (2) assessments of the association between group cohesion ratings and intervention outcomes of maternal self-evaluations of well-being (mood, self-esteem, and social support) and parenting. Mothers participating in groups completed the Group Atmosphere Scale, a measure of group cohesion, post-group. Overall, most participants provided strong ratings of group cohesion. Significant associations were found between group cohesion and specific positive outcomes. This suggests a positive association between group cohesion and mood, self-esteem, social support, and parenting, in this trial.

  15. γ-Irradiation assisted synthesis of graphene oxide sheets supported Ag nanoparticles with single crystalline structure and parabolic distribution from interlamellar limitation

    Energy Technology Data Exchange (ETDEWEB)

    Yue, Yunhao; Zhou, Baoming; Shi, Jie; Chen, Cheng; Li, Nan; Xu, Zhiwei, E-mail: xuzhiwei@tjpu.edu.cn; Liu, Liangsen; Kuang, Liyun; Ma, Meijun; Fu, Hongjun

    2017-05-01

    Highlights: • Graphene oxide sheets supported Ag nanoparticles composites are successfully prepared via γ-irradiation without surfactant or functional agent. • Ag nanoparticles exhibit single crystalline structure and parabolic distribution on the surface of graphene oxide sheets. • Proposing a view that the growth of intercellular AgNPs can be limited by graphite oxide. - Abstract: This paper reported a method to fabricate graphene oxide sheets supported Ag nanoparticles (AgNPs/GOS) with single crystalline structure and parabolic distribution without surfactant or functional agent. We used imidazole silver nitrate as intercalation precursor into the layers of graphite oxide, and subsequently reduction and growth of interlamellar AgNPs were induced via γ-irradiation. The results illustrated that the synergism of interlamellar limitation of graphite oxide and fragmentation ability of γ-irradiation could prevent coalescent reaction of AgNPs with other oligomeric clusters, and the single crystalline and small-sized (below 13.9 nm) AgNPs were prepared. Moreover, the content and size of AgNPs exhibited parabolic distribution on GOS surface because the graphite oxide exfoliated to GOS from the edge to the central area of layers. In addition, complete exfoliation degree of GOS and large-sized AgNPs were obtained simultaneously under suitable silver ions concentration. Optimized composites exhibited outstanding surface-enhanced Raman scattering properties for crystal violet with enhancement factor of 1.3 × 10{sup 6} and detection limit of 1.0 × 10{sup −7} M, indicating that the AgNPs/GOS composites could be applied to trace detection of organic dyes molecules. Therefore, this study presented a strategy for developing GOS supported nanometal with single crystalline structure and parabolic distribution based on γ-irradiation.

  16. γ-Irradiation assisted synthesis of graphene oxide sheets supported Ag nanoparticles with single crystalline structure and parabolic distribution from interlamellar limitation

    International Nuclear Information System (INIS)

    Yue, Yunhao; Zhou, Baoming; Shi, Jie; Chen, Cheng; Li, Nan; Xu, Zhiwei; Liu, Liangsen; Kuang, Liyun; Ma, Meijun; Fu, Hongjun

    2017-01-01

    Highlights: • Graphene oxide sheets supported Ag nanoparticles composites are successfully prepared via γ-irradiation without surfactant or functional agent. • Ag nanoparticles exhibit single crystalline structure and parabolic distribution on the surface of graphene oxide sheets. • Proposing a view that the growth of intercellular AgNPs can be limited by graphite oxide. - Abstract: This paper reported a method to fabricate graphene oxide sheets supported Ag nanoparticles (AgNPs/GOS) with single crystalline structure and parabolic distribution without surfactant or functional agent. We used imidazole silver nitrate as intercalation precursor into the layers of graphite oxide, and subsequently reduction and growth of interlamellar AgNPs were induced via γ-irradiation. The results illustrated that the synergism of interlamellar limitation of graphite oxide and fragmentation ability of γ-irradiation could prevent coalescent reaction of AgNPs with other oligomeric clusters, and the single crystalline and small-sized (below 13.9 nm) AgNPs were prepared. Moreover, the content and size of AgNPs exhibited parabolic distribution on GOS surface because the graphite oxide exfoliated to GOS from the edge to the central area of layers. In addition, complete exfoliation degree of GOS and large-sized AgNPs were obtained simultaneously under suitable silver ions concentration. Optimized composites exhibited outstanding surface-enhanced Raman scattering properties for crystal violet with enhancement factor of 1.3 × 10 6 and detection limit of 1.0 × 10 −7 M, indicating that the AgNPs/GOS composites could be applied to trace detection of organic dyes molecules. Therefore, this study presented a strategy for developing GOS supported nanometal with single crystalline structure and parabolic distribution based on γ-irradiation.

  17. Supported Single-Site Ti(IV) on a Metal–Organic Framework for the Hydroboration of Carbonyl Compounds

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Zhiyuan [College; amp, Molecular Sciences, Institute of Advanced Studies, Wuhan University, Wuhan 430072, PR China; Chemical; amp, Engineering Division, Argonne National Laboratory, Lemont, Illinois 60439, United States; Liu, Dong [College; amp, Molecular Sciences, Institute of Advanced Studies, Wuhan University, Wuhan 430072, PR China; Chemical; amp, Engineering Division, Argonne National Laboratory, Lemont, Illinois 60439, United States; Camacho-Bunquin, Jeffrey [Chemical; amp, Engineering Division, Argonne National Laboratory, Lemont, Illinois 60439, United States; Zhang, Guanghui [Department; Yang, Dali [College; amp, Molecular Sciences, Institute of Advanced Studies, Wuhan University, Wuhan 430072, PR China; Chemical; amp, Engineering Division, Argonne National Laboratory, Lemont, Illinois 60439, United States; López-Encarnación, Juan M. [Chemical; amp, Engineering Division, Argonne National Laboratory, Lemont, Illinois 60439, United States; Department; Xu, Yunjie [Department; Ferrandon, Magali S. [Chemical; amp, Engineering Division, Argonne National Laboratory, Lemont, Illinois 60439, United States; Niklas, Jens [Chemical; amp, Engineering Division, Argonne National Laboratory, Lemont, Illinois 60439, United States; Poluektov, Oleg G. [Chemical; amp, Engineering Division, Argonne National Laboratory, Lemont, Illinois 60439, United States; Jellinek, Julius [Chemical; amp, Engineering Division, Argonne National Laboratory, Lemont, Illinois 60439, United States; Lei, Aiwen [College; amp, Molecular Sciences, Institute of Advanced Studies, Wuhan University, Wuhan 430072, PR China; Chemical; amp, Engineering Division, Argonne National Laboratory, Lemont, Illinois 60439, United States; Bunel, Emilio E. [Chemical; amp, Engineering Division, Argonne National Laboratory, Lemont, Illinois 60439, United States; Delferro, Massimiliano [Chemical; amp, Engineering Division, Argonne National Laboratory, Lemont, Illinois 60439, United States

    2017-10-10

    ABSTRACT: A stable and structurally well-defined titanium alkoxide catalyst supported on a metal-organic-framework (MOF) of UiO-67 topology (ANL1-Ti(OiPr)2) was synthesized and fully characterized by a variety of analytical and spectroscopic techniques, including BET, TGA, PXRD, XAS, DRIFT, SEM, and DFT computations. The Ti-functionalized MOF was demonstrated active for the catalytic hydroboration of a wide range of aldehydes and ketones with HBpin as the boron source. Compared to traditional homogeneous and supported hydroboration catalysts, ANL1-Ti(OiPr)2 is completely recyclable and reusable, making it a promising hydroboration catalyst alternative for green and sustainable chemical synthesis. DFT calculations suggest that the catalytic hydroboration proceeds via a (1) hydride transfer between the active Ti-hydride species and a carbonyl moiety (rate determining step), and (2) alkoxide transfer (intramolecular σ-bond metathesis) to generate the boronate ester product.

  18. γ-Irradiation assisted synthesis of graphene oxide sheets supported Ag nanoparticles with single crystalline structure and parabolic distribution from interlamellar limitation

    Science.gov (United States)

    Yue, Yunhao; Zhou, Baoming; Shi, Jie; Chen, Cheng; Li, Nan; Xu, Zhiwei; Liu, Liangsen; Kuang, Liyun; Ma, Meijun; Fu, Hongjun

    2017-05-01

    This paper reported a method to fabricate graphene oxide sheets supported Ag nanoparticles (AgNPs/GOS) with single crystalline structure and parabolic distribution without surfactant or functional agent. We used imidazole silver nitrate as intercalation precursor into the layers of graphite oxide, and subsequently reduction and growth of interlamellar AgNPs were induced via γ-irradiation. The results illustrated that the synergism of interlamellar limitation of graphite oxide and fragmentation ability of γ-irradiation could prevent coalescent reaction of AgNPs with other oligomeric clusters, and the single crystalline and small-sized (below 13.9 nm) AgNPs were prepared. Moreover, the content and size of AgNPs exhibited parabolic distribution on GOS surface because the graphite oxide exfoliated to GOS from the edge to the central area of layers. In addition, complete exfoliation degree of GOS and large-sized AgNPs were obtained simultaneously under suitable silver ions concentration. Optimized composites exhibited outstanding surface-enhanced Raman scattering properties for crystal violet with enhancement factor of 1.3 × 106 and detection limit of 1.0 × 10-7 M, indicating that the AgNPs/GOS composites could be applied to trace detection of organic dyes molecules. Therefore, this study presented a strategy for developing GOS supported nanometal with single crystalline structure and parabolic distribution based on γ-irradiation.

  19. Strategies for Balance maintenance in Different Support Surfaces - Mechanisms, Trainability and Transfer to Single-Leg Landing Performance

    DEFF Research Database (Denmark)

    Silva, Priscila de Brito

    2016-01-01

    Well-adapted control of posture is crucial for the human body function. Postural control relates to coordination of body segments to maintain or restore balance, making the execution of a task safer with less effort. This PhD thesis focuses on the effects of different support surfaces on postural...... that postural control strategies are affected by surface stability and optimized with training, but also that the adaptations to training are transferred to movement strategies of sports gestures not involved in the training. This thesis offers a new perspective on how balance training provides protective...

  20. Effect of Abutment Height on Retention of Single Cementretained, Wide- and Narrow-platform Implant-supported Restorations

    Directory of Open Access Journals (Sweden)

    Fariba Saleh Saber

    2012-06-01

    Full Text Available Background and aims. In contrast to prepared natural dentin abutments, little is known concerning factors influencing the retention of fixed prostheses cemented to implant abutments. The aim of this study was to investigate the effect of implant abutment height on the retention of single castings cemented to wide and narrow platform implant abutments. Materials and methods. Thirty-six parallel-sided abutments (Biohorizon Straight Abutment of narrow platform (NP and wide platform (WP sizes with their analogs were used. In each group of platform size, abutments were prepared with axial wall heights of 5, 4, 3, 2 mm (n=9. On the whole 72 castings were constructed, which incorporated an attachment to allow removal. Castings were cemented to abutments with TempBond®. A uniaxial tensile force was applied to the crown using an Instron machine until cement failure occurred. Analysis of variance of the models were fit to determine the effect of height of abutment of the restorations on the mean tensile strength (α=0.05. Results. The mean peak removal force for corresponding abutments was significantly different (P NP; (2 with alteration of axial wall height for NP: 5 mm > 4 mm > 3 mm = 2 mm and for WP: 5 mm > 4 mm = 3 mm = 2 mm. Conclusion. The retention of NP cement-retained restorations is influenced by the wall height but not in same manner as WP. Restorations of narrow-platform size with longer abutment exhibited higher tensile resistance to dislodgement.

  1. XRLINE, a program to evaluate the crystallite size of supported metal catalysts by single X-ray profile Fourier analysis

    International Nuclear Information System (INIS)

    Aldea, N.; Indrea, E.

    1990-01-01

    The computer program presented is based on the Fourier analysis of a singel X-ray diffraction profile. An X-ray diffraction method is presented which is capable of determining the average particle size, microstrain, stacking fault probability as well as the particle size distribution function in crystalline materials. The main numerical methods used are: (i) Smoothing and interpolation by 3rd-order piecewise polynomial functions or by cubic splines with the least squares method; (ii) numerical integration by successive five points formulae and numerical derivative by cubic splines with the least squares method; (iii) estimation of parameters by the weighted least squares method. The results for supported platinum catalysts used in the H/D isotopic exchange reaction are illustrated. (orig.)

  2. Modeling intraparticle transports during propylene polymerizations using supported metallocene and dual function metallocene as catalysts: Single particle model

    Directory of Open Access Journals (Sweden)

    Li Hua-Rong

    2014-01-01

    Full Text Available Two improved multigrain models (MGMs for preparing homopolypropylene and long chain branched polypropylene via propylene polymerization using silica-supported metallocene or dual function metallocene as catalysts are presented in this paper. The presented models are used to predict the intraparticle flow fields involved in the polymerizations. The simulation results show that the flow field distributions involve dare basically identical. The results also show that both the two polymerization processes have an initiation stage and the controlling step for them is reaction-diffusion-reaction with the polymerization proceeding. Furthermore, the simulation results show that the intra particle mass transfer resistance has significant effect on the polymerization but the heat transfer resistance can be ignored.

  3. Analysis of Positive Selection at Single Nucleotide Polymorphisms Associated with Body Mass Index Does Not Support the "Thrifty Gene" Hypothesis.

    Science.gov (United States)

    Wang, Guanlin; Speakman, John R

    2016-10-11

    The "thrifty gene hypothesis" suggests genetic susceptibility to obesity arises because of positive selection for alleles that favored fat deposition and survival during famines. We used public domain data to locate signatures of positive selection based on derived allele frequency, genetic diversity, long haplotypes, and differences between populations at SNPs identified in genome-wide association studies (GWASs) for BMI. We used SNPs near the lactase (LCT), SLC24A5, and SLC45A2 genes as positive controls and 120 randomly selected SNPs as negative controls. We found evidence for positive selection (p positive selection for the protective allele (i.e., for leanness). The widespread absence of signatures of positive selection, combined with selection favoring leanness at some alleles, does not support the suggestion that obesity provided a selective advantage to survive famines, or any other selective advantage. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. Nedaplatin as a Single-Agent Chemotherapy May Support Palliative Therapy for Patients with Adenoid Cystic Carcinoma: A Case Report

    Directory of Open Access Journals (Sweden)

    Hiroyuki Hirakawa

    2017-08-01

    Full Text Available Adenoid cystic carcinoma (ACC is a rare form of adenocarcinoma, which is a broad term describing any cancer that begins in the glandular tissues. It can be found in the head and neck. We report a patient with recurrent ACC arising from the submandibular gland, treated with 100 mg/m2 nedaplatin every 4 weeks. Although our patient’s lactate dehydrogenase levels, which is produced by ACC, showed a rising trend throughout the treatment, the level decreased for approximately 2 weeks immediately after administration of nedaplatin every 4 weeks. Thus, there is a possibility that the agent may be effective. Complications such as anorexia and nausea were observed, but they were tolerated and manageable. Nedaplatin may be considered as a supportive agent during palliative therapy for patients with ACC. More clinical trials regarding nedaplatin are necessary, as this study may indicate that a medical approach works well for ACC.

  5. Method for developing an optimal emergence profile using heat-polymerized provisional restorations for single-tooth implant-supported restorations.

    Science.gov (United States)

    Macintosh, Daniel C T; Sutherland, Mark

    2004-03-01

    This article describes a method for creating an improved emergence profile with single-tooth, implant-supported restorations. An easily trimmed silicone gingival substitute is used to allow polymerization of acrylic resin provisional restorations to achieve control of the emergence profile. Gingival trauma is minimized by eliminating intraoral use of monomer and minimizing surgical procedures. Provisional restorations can be assessed to ensure the contour is acceptable and the trimmed gingival substitute can be used to fabricate a similar profile in the definitive prosthesis. The provisional restorations may be used instead of standard prefabricated healing abutments to guide the healing contours of the peri-implant gingival tissue.

  6. Analyses of 32 Loci Clarify Phylogenetic Relationships among Trypanosoma cruzi Lineages and Support a Single Hybridization prior to Human Contact

    Science.gov (United States)

    Flores-López, Carlos A.; Machado, Carlos A.

    2011-01-01

    Background The genetic diversity of Trypanosoma cruzi, the etiological agent of Chagas disease, has been traditionally divided in two major groups, T. cruzi I and II, corresponding to discrete typing units TcI and TcII-VI under a recently proposed nomenclature. The two major groups of T. cruzi seem to differ in important biological characteristics, and are thus thought to represent a natural division relevant for epidemiological studies and development of prophylaxis. To understand the potential connection between the different manifestations of Chagas disease and variability of T. cruzi strains, it is essential to have a correct reconstruction of the evolutionary history of T. cruzi. Methodology/Principal Findings Nucleotide sequences from 32 unlinked loci (>26 Kilobases of aligned sequence) were used to reconstruct the evolutionary history of strains representing the known genetic variability of T. cruzi. Thorough phylogenetic analyses show that the original classification of T. cruzi in two major lineages does not reflect its evolutionary history and that there is only strong evidence for one major and recent hybridization event in the history of this species. Furthermore, estimates of divergence times using Bayesian methods show that current extant lineages of T. cruzi diverged very recently, within the last 3 million years, and that the major hybridization event leading to hybrid lineages TcV and TcVI occurred less than 1 million years ago, well before the contact of T. cruzi with humans in South America. Conclusions/Significance The described phylogenetic relationships among the six major genetic subdivisions of T. cruzi should serve as guidelines for targeted epidemiological and prophylaxis studies. We suggest that it is important to reconsider conclusions from previous studies that have attempted to uncover important biological differences between the two originally defined major lineages of T. cruzi especially if those conclusions were obtained from single

  7. A simplified method to develop optimal gingival contours for the single implant-supported, metal-ceramic crown in the aesthetic zone.

    Science.gov (United States)

    Kinsel, Richard P; Capoferri, Daniele

    2008-05-01

    Prosthetic replacement of the missing single maxillary central incisor with an implant-supported crown represents a profound aesthetic challenge for the restorative dentist, laboratory technician, and surgeon. In addition to the visual fidelity of color, translucency, contour, and surface texture, the proper soft tissue outline is sacrosanct to the illusion of a natural tooth. The contrast between the uniformly round shoulder of the implant and the tooth's curvilinear cementoenamel junction is particularly problematic. This clinical report demonstrates a simplified method that precisely controls the facial gingival and proximal soft tissue contours for implant-supported, metal-ceramic crowns in the aesthetic zone, using the cervical anatomy of the maxillary incisor tooth as a guide. A new role for the provisional crown that is intended to maximize the volume of keratinized tissue is also described.

  8. Correlations between fracture load of zirconia implant supported single crowns and mechanical properties of restorative material and cement.

    Science.gov (United States)

    Rohr, Nadja; Märtin, Sabrina; Fischer, Jens

    2017-11-23

    Zirconia implants that were restored with veneered zirconia displayed severe chipping rates of the restorations in clinical studies. Purpose of this study was to evaluate the fracture load of different zirconia implant supported monolithic crown materials (zirconia, alumina, lithium disilicate, feldspar ceramic and polymer-infiltrated ceramic) cemented with various cements (Harvard LuteCem SE, Harvard Implant Semi-permanent, Multilink Automix, VITA Adiva F-Cem). Flexural strength and fracture toughness of crown materials and compressive strength of the cements were measured. Fracture load values of crowns fabricated from lithium disilicate, feldspar ceramic and polymer-infiltrated ceramic were increased when cement with high compressive strength was used. Fracture loads for zirconia and alumina crowns were not influenced by the cement. Flexural strength and fracture toughness of the ceramics correlated linearly with the respective fracture load when using adhesive cement with high compressive strength. To achieve sufficient fracture load values, cementation with adhesive cement is essential for feldspar and polymer-infiltrated ceramic.

  9. Marginal Fit Metal-Ceramic and In-Ceram Single Crown Cement retained in Implant-supported Abutments.

    Science.gov (United States)

    Valente, Valdimar S; Francischone, Carlos E; Vilarinho Soares de Moura, C D; Francischone, C E; Silva, Antonio M; Ribeiro, Izabella S; Filho, E M Maia; Bandéca, Matheus C; Tonetto, Mateus R; de Jesus Tavarez, R R

    2016-12-01

    This study evaluated the cervical fit of cemented metal-ceramic and In-Ceram implant-supported crowns, before and after the cementing procedure. Twenty crowns cemented on implant abutments are divided into two groups (n = 10): Group 1 -cemented metal-ceramic crowns and group 2 - cemented In-Ceram crowns. The marginal adaptations before and after cementation were evaluated in a comparison microscope with an error of 1 μm. All crowns were cemented with zinc phosphate cement. The cervical misalignment of cemented crowns before cementation (52.65 ± 11.83 and 85.73 ± 14.06 μm) was lower than that after cementation (66.80 ± 15.86 and 89.36 ± 22.66 μm). The cementing procedure interferes with the marginal fit of cemented crowns on implant abutments, with the prosthesis having better adaptation before cementation. Cemented metal-ceramic crowns exhibited better cervical adaptation than In-Ceram crowns cemented before and after the cementing procedure. The maintenance of gum health and the longevity of prosthetic restorations are closely related to the restoration's marginal integrity.

  10. CO oxidation mechanism on the γ-Al{sub 2}O{sub 3} supported single Pt atom: First principle study

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Hongwei, E-mail: gaohongw369@ms.xjb.ac.cn

    2016-08-30

    Highlights: • DFT studied on CO oxidation mechanism on Pt/γ-Al{sub 2}O{sub 3} catalyst. • DFT studied on the adsorption properties of single Pt on Pt/γ-Al{sub 2}O{sub 3} catalyst. • Pt adsorptions on the Al-terminated surface are more favorable than the ones on the O-terminated surface. • The reactive O*−O−C*=O intermediate mechanism is the dominant reaction pathway for CO oxidation on Pt/γ-Al{sub 2}O{sub 3}. - Abstract: Understanding the role of metal-support interaction for the supported single-atom catalysts is very important in heterogeneous catalysis. Here, Three different CO oxidation mechanisms on Pt/γ-Al{sub 2}O{sub 3} catalyst were probed by periodic density functional theory (DFT) calculations in detail, namely the reactive O*−O−C*=O intermediate mechanism, the reactive CO{sub 3} intermediate mechanism and the Pt-Al{sup 3+} double sites mechanism. According to the calculated results analysis, we concluded that the dominant reaction pathway at the low temperatures is the reactive O*−O−C*=O intermediate mechanism. Our results are in very good agreement with the experimental evidence for O*−O−C*=O coverage on Pt/γ-Al{sub 2}O{sub 3} at room temperature by an in situ diffuse reflectance infrared detector.

  11. Single-Tooth Rehabilitations Supported by Dental Implants Used in an Immediate-Provisionalization Protocol: Report on Long-Term Outcome with Retrospective Follow-Up.

    Science.gov (United States)

    Maló, Paulo; de Araújo Nobre, Miguel; Lopes, Armando; Ferro, Ana; Gravito, Inês

    2015-10-01

    There is a need for long-term studies evaluating the outcome of single-tooth rehabilitations supported by dental implants in immediate loading. To report the long-term outcome (in excess of 5 years) of single-tooth rehabilitations supported by dental implants in an immediate-provisionalization protocol. This retrospective cohort study included 332 consecutive patients (189 females and 143 males) with an average age of 47 years (range: 16 to 82 years) who were rehabilitated between 1996 and 2006 with 594 single crowns supported by dental implants in immediate loading. Implant success rates were calculated based on implant function and using life tables. Marginal bone levels were measured at 5 and 10 years. Mechanical and biological complications were calculated for the follow-up period between implant insertion and 5 years and every 6 months thereafter. Fifty-four patients dropped out of the study (16.5%). Nineteen patients lost a total of 25 implants (n = 23 in the maxilla; n = 2 in the mandible), rendering a cumulative survival rate of 95.7% at both 5 and 10 years of follow-up. The mean marginal bone levels were 1.56 mm (standard deviation 0.78 mm) and 1.75 mm (standard deviation 0.29 mm) at 5 and 10 years of follow-up. Mechanical complications occurred in 83 patients and 116 implants (19.5%) up to the 10-year follow-up, namely prosthetic screw loosening (2.4%), abutment complications (4.4%), fracture of provisional crowns (9.6%), and fracture of definitive ceramic crowns (3.5%). Biological complications occurred in 58 patients and 79 implants (13.3%) up to the 10-year follow-up, with the majority consisting in peri-implant pathology. Considering the high survival rates and stable marginal bone levels after 10 years, it can be concluded within the limitations of the present study that replacement of single teeth with dental implants in an immediate-provisionalization protocol is a viable and safe treatment option for both maxilla and mandible.

  12. Clinical evaluation of 209 all-ceramic single crowns cemented on natural and implant-supported abutments with different luting agents: a 6-year retrospective study.

    Science.gov (United States)

    Sorrentino, Roberto; Galasso, Luigi; Tetè, Stefano; De Simone, Giorgio; Zarone, Fernando

    2012-04-01

    The Procera AllCeram™ system (Nobel Biocare AB, Göteborg, Sweden) is a valid alternative to metal-ceramic restorations. However, limited long-term data of its use for single crowns on natural and implant-supported abutments are available. The present study aimed at evaluating the clinical performances of Procera AllCeram single crowns in both anterior and posterior regions of the oral cavity either on natural tooth or implant abutments over a period of 6 years. Two hundred nine single crowns were fabricated and used in 112 patients. Zinc phosphate and resin luting agents were used to cement the restorations. The crowns were evaluated according to the California Dental Association's quality assessment system. Three crowns were lost at follow-up. Of the 206 restorations, which completed the 6-year follow-up, 9 crowns were affected by mechanical complications and 7 crowns failed. All surviving crowns were ranked as either excellent or acceptable. Cumulative survival and success rates of 95.2 and 90.9%, respectively, were recorded. Within the limitations of the present study, Procera AllCeram crowns proved to be a reliable clinical option to restore both anterior and posterior missing teeth either on natural or implant abutments. The resin cement used in the present study performed better than the zinc phosphate luting agent. © 2009 Wiley Periodicals, Inc.

  13. Impact of prosthetic material on mid- and long-term outcome of dental implants supporting single crowns and fixed partial dentures: A systematic review and meta-analysis.

    Science.gov (United States)

    Abou-Ayash, Samir; Strasding, Malin; Rücker, Gerta; Att, Wael

    The impact of prosthetic material selection on implant survival is not clear. The current criteria for choosing a prosthetic material seem to be based on clinician preferences. This systematic review aims to evaluate the impact of restorative materials on the mid- and long-term survival of implants supporting single crowns and fixed partial dentures. Hand and MEDLINE searches were performed to identify relevant literature for single crowns (SC) and fixed partial dentures (FPD). Further inclusion criteria were a mean follow-up period of at least 3 years, the inclusion of at least 10 patients in a relevant study cohort, and a clear description of prosthesis type and prosthetic material. A total of 63 studies for the SC group and 11 studies for the FPD group were included. Full arch restorations were not included. The materials utilised in the SC group were metal-ceramic (precious and non-precious), lithium-disilicate, veneered zirconia, veneered alumina, and nanoceramics. The materials used in the FPD group were metal-ceramic (precious), veneered titanium, metal-resin (precious), and veneered zirconia. No significant impact on the prosthetic material relating to mid- or long-term implant survival was identified. Furthermore, there were no statistically significant differences between the survival rates of the dental prostheses made from different materials (SC and FPD group). Single crowns made of nanoceramics showed a higher risk for decementation relative to other materials (0.80, 95% CI [0.67; 0.89]; P prosthetic material selection has no influence on mid- and long-term survival of implants restored with single crowns and fixed partial dentures. Similarly, the prosthetic material seems to have no significant impact on prosthetic survival rates. Further research is required to provide more evidence regarding the impact of the prosthetic material on long-term outcome. Conflict-of-interest statement: The authors declare that they have no conflict of interest.

  14. Effect of using a laryngeal tube on the no-flow time in a simulated, single-rescuer, basic life support setting with inexperienced users.

    Science.gov (United States)

    Meyer, O; Bucher, M; Schröder, J

    2016-03-01

    The laryngeal tube (LT) is a recommended alternative to endotracheal intubation during advanced life support (ALS). Its insertion is relatively simple; therefore, it may also serve as an alternative to bag mask ventilation (BMV) for untrained personnel performing basic life support (BLS). Data support the influence of LT on the no-flow time (NFT) compared with BMV during ALS in manikin studies. We performed a manikin study to investigate the effect of using the LT for ventilation instead of BMV on the NFT during BLS in a prospective, randomized, single-rescuer study. All 209 participants were trained in BMV, but were inexperienced in using LT; each participant performed BLS during a 4-min time period. No significant difference in total NFT (LT: mean 81.1 ± 22.7 s; BMV: mean 83.2 ± 13.1 s, p = 0.414) was found; however, significant differences in the later periods of the scenario were identified. While ventilating with the LT, the proportion of chest compressions increased significantly from 67.2 to 73.2%, whereas the proportion of chest compressions increased only marginally when performing BMV. The quality of the chest compressions and the associated ventilation rate did not differ significantly. The mean tidal volume and mean minute volume were significantly lower when performing BMV. The NFT was significantly shorter in the later periods in a single-rescuer, cardiac arrest scenario when using an LT without previous training compared with BMV with previous training. A possible explanation for this result may be the complexity and workload of alternating tasks (e.g., time loss when reclining the head and positioning the mask for each ventilation during BMV).

  15. Fracture strength and failure mode of maxillary implant-supported provisional single crowns: a comparison of composite resin crowns fabricated directly over PEEK abutments and solid titanium abutments.

    Science.gov (United States)

    Santing, Hendrik Jacob; Meijer, Henny J A; Raghoebar, Gerry M; Özcan, Mutlu

    2012-12-01

    Polyetheretherketone (PEEK) temporary abutments have been recently introduced for making implant-supported provisional single crowns. Little information is available in the dental literature on the durability of provisional implant-supported restorations. The objectives of this study were to evaluate the fracture strength of implant-supported composite resin crowns on PEEK and solid titanium temporary abutments, and to analyze the failure types. Three types of provisional abutments, RN synOcta Temporary Meso Abutment (PEEK; Straumann), RN synOcta Titanium Post for Temporary Restorations (Straumann), and Temporary Abutment Engaging NobRplRP (Nobel Biocare) were used, and provisional screw-retained crowns using composite resin (Solidex) were fabricated for four different locations in the maxilla. The specimens were tested in a universal testing machine at a crosshead speed of 1 mm/minute until fracture occurred. The failure types were analyzed and further categorized as irreparable (Type 1) or reparable (Type 2). No significant difference was found between different abutment types. Only for the position of the maxillary central incisor, composite resin crowns on PEEK temporary abutments showed significantly lower (p Provisional crowns on PEEK abutments showed similar fracture strength as titanium temporary abutments except for central incisors. Maxillary right central incisor composite resin crowns on PEEK temporary abutments fractured below the mean anterior masticatory loading forces reported to be approximately 206 N. © 2010 Wiley Periodicals, Inc.

  16. Boosted Regression Trees Outperforms Support Vector Machines in Predicting (Regional) Yields of Winter Wheat from Single and Cumulated Dekadal Spot-VGT Derived Normalized Difference Vegetation Indices

    Science.gov (United States)

    Stas, Michiel; Dong, Qinghan; Heremans, Stien; Zhang, Beier; Van Orshoven, Jos

    2016-08-01

    This paper compares two machine learning techniques to predict regional winter wheat yields. The models, based on Boosted Regression Trees (BRT) and Support Vector Machines (SVM), are constructed of Normalized Difference Vegetation Indices (NDVI) derived from low resolution SPOT VEGETATION satellite imagery. Three types of NDVI-related predictors were used: Single NDVI, Incremental NDVI and Targeted NDVI. BRT and SVM were first used to select features with high relevance for predicting the yield. Although the exact selections differed between the prefectures, certain periods with high influence scores for multiple prefectures could be identified. The same period of high influence stretching from March to June was detected by both machine learning methods. After feature selection, BRT and SVM models were applied to the subset of selected features for actual yield forecasting. Whereas both machine learning methods returned very low prediction errors, BRT seems to slightly but consistently outperform SVM.

  17. An analysis of reliability and validity of the papilla index score of implant-supported single crowns of maxillary central incisors

    DEFF Research Database (Denmark)

    Peng, Min; Fei, Wei; Hosseini, Mandana

    2012-01-01

    Objectives: To test the reliability and validity of the papilla index scores of the implant-supported single crowns (ISSCs) of maxillary central incisors. Materials and Methods: Twenty-five patients with 25 ISSCs were included. Two prosthodontists evaluated the papilla index score (PIS) of three...... fill percent (PP) was calculated. The validity of PIS was tested against the corresponding papilla fill percent (PP) by using the Spearman correlation analysis. Results: The intra-observer agreement was >70% in 4/5 and >50% in all observations, the pooled Cohen’s ¿ was 0.64 and 0.70 for two observers...... inter-observer agreement. The PIS score demonstrated significant correlation to the corresponding PP value (rs=.567, p=.000). Conclusions: The feasibility, reliability and validity of the PIS made the parameter useful for quality control of the pri-implant soft tissue of ISSCs....

  18. An Up-to-15-Year Comparison of the Survival and Complication Burden of Three-Unit Tooth-Supported Fixed Dental Prostheses and Implant-Supported Single Crowns.

    Science.gov (United States)

    Walton, Terry R

    2015-01-01

    To assess and compare the outcomes and economic complication burden of three-unit tooth-supported fixed dental prostheses (TFDPs) and implant-supported single crowns (ISCs) provided to a sequential cohort in a specialist prosthodontic practice over a 15-year period. Sequential patients requiring replacement of a single missing tooth between 1996 and 2010 with a metal-ceramic three-unit TFDP (n = 145 patients, n = 174 prostheses) or ISC (n = 174 patients, n = 220 prostheses) were included. Prostheses subjectively judged at insertion to have an unfavorable 10-year prognosis (17 TFDPs, 0 ISCs) were removed from statistical analyses. The estimated cumulative survival (ECS) was calculated with the life table actuarial method and standard errors calculated with the Greenwood formula. Differences in outcomes between all prostheses and those replacing only anterior or only posterior teeth were assessed with the log rank test. Complication incidence, severity, and economic burden, measured in time/cost accounting units (TAUs), were tallied and compared descriptively. The 15-year ECS did not differ for 112 TFDPs (92.75% ± 3.28%) and 81 ISCs (95.95% ± 2.92%) replacing posterior teeth. However, the 15-year ECS was significantly greater for 139 ISCs (93.33% ± 6.44%) than for 45 TFDPs (82.82% ± 6.50%) replacing anterior teeth. The economic burden of nonterminal complications for both prostheses was low (mean = 0.3 and 0.2 TAUs per prosthesis for TFDPs and ISCs, respectively). This equated to 3 TAUs/100 years in clinical service and 4 TAUs/100 years in clinical service for the TFDPs and ISCs, respectively. The survival of three-unit TFDPs and ISCs over 15 years was not statistically different when replacing posterior teeth, but ISCs survived significantly better when replacing anterior teeth. The complication rates of the TFDPs and ISCs were similar, but the economic burden for the TFDPs was greater.

  19. Experimental zirconia abutments for implant-supported single-tooth restorations in esthetically demanding regions: 4-year results of a prospective clinical study.

    Science.gov (United States)

    Glauser, Roland; Sailer, Irena; Wohlwend, Arnold; Studer, Stephan; Schibli, Monica; Schärer, Peter

    2004-01-01

    This prospective clinical study evaluated an experimental implant abutment made of densely sintered zirconia with respect to peri-implant hard and soft tissue reaction as well as fracture resistance over time. Twenty-seven consecutively treated patients with 54 single-tooth implants were included. Zirconia abutment ingots were individually shaped and set on the implants with gold screws. All-ceramic (Empress I) crowns were cemented using a composite cement. At the 1- and 4-year examinations, reconstructions were evaluated for technical problems (fracture of abutment or crown, loosening of abutment screw). Modified Plaque and simplified Gingival Indices were recorded at implants and neighboring teeth, and peri-implant bone levels were radiographically determined. All but 1 of the 27 patients with 53 restorations could be evaluated at 1 year, and 36 restorations in 18 patients were evaluated 4 years after abutment and crown insertion. The median observation period for the reconstructions was 49.2 months. No abutment fractures occurred. Abutment screw loosening was reported for 2 restorations at 8 months and 27 months, respectively. Mean Plaque Index was 0.4 (SD 0.6) at abutments and 0.5 (SD 0.6) at teeth; mean Gingival Index was 0.7 (SD 0.5) at abutments and 0.9 (SD 0.5) at teeth. Mean marginal bone loss measured 1.2 mm (SD 0.5) after 4 years of functional loading. Zirconia abutments offered sufficient stability to support implant-supported single-tooth reconstructions in anterior and premolar regions. The soft and hard tissue reaction toward zirconia was favorable.

  20. Five-year results of a randomized controlled clinical trial comparing zirconia and titanium abutments supporting single-implant crowns in canine and posterior regions.

    Science.gov (United States)

    Zembic, Anja; Bösch, Adrian; Jung, Ronald E; Hämmerle, Christoph H F; Sailer, Irena

    2013-04-01

    To test the survival rates, and the technical and biological complication rates of customized zirconia and titanium abutments 5 years after crown insertion. Twenty-two patients with 40 single implants in maxillary and mandibular canine and posterior regions were included. The implant sites were randomly assigned to zirconia abutments supporting all-ceramic crowns or titanium abutments supporting metal-ceramic crowns. Clinical examinations were performed at baseline, and at 6, 12, 36 and 60 months of follow-up. The abutments and reconstructions were examined for technical and/or biological complications. Probing pocket depth (PPD), plaque control record (PCR) and Bleeding on Probing (BOP) were assessed at abutments (test) and analogous contralateral teeth (control). Radiographs of the implants revealed the bone level (BL) on mesial (mBL) and distal sides (dBL). Data were statistically analyzed with nonparametric mixed models provided by Brunner and Langer and STATA (P zirconia and 10 titanium abutments were available at a mean follow-up of 5.6 years (range 4.5-6.3 years). No abutment fracture or loss of a reconstruction occurred. Hence, the survival rate was 100% for both. Survival of implants supporting zirconia abutments was 88.9% and 90% for implants supporting titanium abutments. Chipping of the veneering ceramic occurred at three metal-ceramic crowns supported by titanium abutments. No significant differences were found at the zirconia and titanium abutments for PPD (meanPPDZrO2 3.3 ± 0.6 mm, mPPDTi 3.6 ± 1.1 mm), PCR (mPCRZrO2 0.1 ± 0.3, mPCRTi 0.3 ± 0.2) and BOP (mBOPZrO2 0.5 ± 0.3, mBOPTi 0.6 ± 0.3). Moreover, the BL was similar at implants supporting zirconia and titanium abutments (mBLZrO2 1.8 ± 0.5, dBLZrO2 2.0 ± 0.8; mBLTi 2.0 ± 0.8, dBLTi 1.9 ± 0.8). There were no statistically or clinically relevant differences between the 5-year survival rates, and the technical and biological complication rates of zirconia and

  1. Emotion Recognition from Single-Trial EEG Based on Kernel Fisher’s Emotion Pattern and Imbalanced Quasiconformal Kernel Support Vector Machine

    Directory of Open Access Journals (Sweden)

    Yi-Hung Liu

    2014-07-01

    Full Text Available Electroencephalogram-based emotion recognition (EEG-ER has received increasing attention in the fields of health care, affective computing, and brain-computer interface (BCI. However, satisfactory ER performance within a bi-dimensional and non-discrete emotional space using single-trial EEG data remains a challenging task. To address this issue, we propose a three-layer scheme for single-trial EEG-ER. In the first layer, a set of spectral powers of different EEG frequency bands are extracted from multi-channel single-trial EEG signals. In the second layer, the kernel Fisher’s discriminant analysis method is applied to further extract features with better discrimination ability from the EEG spectral powers. The feature vector produced by layer 2 is called a kernel Fisher’s emotion pattern (KFEP, and is sent into layer 3 for further classification where the proposed imbalanced quasiconformal kernel support vector machine (IQK-SVM serves as the emotion classifier. The outputs of the three layer EEG-ER system include labels of emotional valence and arousal. Furthermore, to collect effective training and testing datasets for the current EEG-ER system, we also use an emotion-induction paradigm in which a set of pictures selected from the International Affective Picture System (IAPS are employed as emotion induction stimuli. The performance of the proposed three-layer solution is compared with that of other EEG spectral power-based features and emotion classifiers. Results on 10 healthy participants indicate that the proposed KFEP feature performs better than other spectral power features, and IQK-SVM outperforms traditional SVM in terms of the EEG-ER accuracy. Our findings also show that the proposed EEG-ER scheme achieves the highest classification accuracies of valence (82.68% and arousal (84.79% among all testing methods.

  2. Findings of a Four-Year Randomized Controlled Clinical Trial Comparing Two-Piece and One-Piece Zirconia Abutments Supporting Single Prosthetic Restorations in Maxillary Anterior Region

    Directory of Open Access Journals (Sweden)

    Guerino Paolantoni

    2016-01-01

    Full Text Available The purpose of this randomized controlled study is to investigate the clinical results obtained over four years and incidence of complications associated with one- versus two-piece custom made zirconia anchorages, in single tooth implant-supported restorations of the maxillary anterior region. Sixty-five patients, with a total of 74 missing maxillary teeth, were selected in the period from February 2007 to July 2010. Two different ways of custom made zirconia abutment and final prosthetic restoration were evaluated: a standard zirconia abutment associated with a pressed layer of lithium disilicate with an all-ceramic cemented restoration versus one-piece restoration with the facing porcelain fired and pressed straight to the custom made zirconia abutment. In 29 cases, the restoration consisted of an all-ceramic restoration for cementation (two pieces; in 45 cases the restoration was a screw-retained restoration (one piece. Three all-ceramic restorations broke during the observation time. Two one-piece restorations fractured after 26 months. At follow-up examination there were no significant differences between one-piece and two-piece groups regarding the PI, BI, and MBL. Awaiting studies with longer follow-up times, a careful conclusion is that zirconia anchorages for single-implant restorations seem to demonstrate good short-term technical and biological results.

  3. Preparation of highly dispersed Ru-Sn bimetallic supported catalysts from the single source precursors Cp(PPh32Ru-SnX3 (X = Cl or Br

    Directory of Open Access Journals (Sweden)

    Ana Cláudia Bernardes Silva

    2003-06-01

    Full Text Available In this work highly dispersed Ru-Sn bimetallic catalysts have been prepared from organobimetallic Cp(PPh32Ru-SnX3 (X = Cl or Br complexes. These single source precursors can be easily impregnated in high surface area supports, such as activated carbon and sol-gel SiO2, and upon controlled thermal treatment the ligands are released as volatile products resulting in the formation of the bimetallic system Ru-Sn. Catalytic reactions, such as hydrodechlorination of CCl4 and chlorobenzene and TPR (Temperature Programmed Reduction experiments carried out with these RuSn catalysts suggested a strong interaction between Ruthenium and Tin. Mössbauer measurements showed that these materials when exposed to air are immediately oxidized to form Sn (IV. It was shown that upon controlled reduction conditions with H2 it is possible to reduce selectively Sn to different oxidation states and different phases. The Sn oxidation state showed significant effect on the catalytic hydrogenation of 1,5-cyclooctadiene. The use of these single source precursors with a controlled decomposition/reduction procedure allows the preparation of unique catalysts with an intimate interaction between the components ruthenium and tin and the possibility of varying the Sn oxidation state around the Ru metal.

  4. Findings of a Four-Year Randomized Controlled Clinical Trial Comparing Two-Piece and One-Piece Zirconia Abutments Supporting Single Prosthetic Restorations in Maxillary Anterior Region

    Science.gov (United States)

    Paolantoni, Guerino; Marenzi, Gaetano; Blasi, Andrea; Mignogna, Jolanda; Sammartino, Gilberto

    2016-01-01

    The purpose of this randomized controlled study is to investigate the clinical results obtained over four years and incidence of complications associated with one- versus two-piece custom made zirconia anchorages, in single tooth implant-supported restorations of the maxillary anterior region. Sixty-five patients, with a total of 74 missing maxillary teeth, were selected in the period from February 2007 to July 2010. Two different ways of custom made zirconia abutment and final prosthetic restoration were evaluated: a standard zirconia abutment associated with a pressed layer of lithium disilicate with an all-ceramic cemented restoration versus one-piece restoration with the facing porcelain fired and pressed straight to the custom made zirconia abutment. In 29 cases, the restoration consisted of an all-ceramic restoration for cementation (two pieces); in 45 cases the restoration was a screw-retained restoration (one piece). Three all-ceramic restorations broke during the observation time. Two one-piece restorations fractured after 26 months. At follow-up examination there were no significant differences between one-piece and two-piece groups regarding the PI, BI, and MBL. Awaiting studies with longer follow-up times, a careful conclusion is that zirconia anchorages for single-implant restorations seem to demonstrate good short-term technical and biological results. PMID:27027093

  5. Numerical Control Machine Tool Fault Diagnosis Using Hybrid Stationary Subspace Analysis and Least Squares Support Vector Machine with a Single Sensor

    Directory of Open Access Journals (Sweden)

    Chen Gao

    2017-03-01

    Full Text Available Tool fault diagnosis in numerical control (NC machines plays a significant role in ensuring manufacturing quality. However, current methods of tool fault diagnosis lack accuracy. Therefore, in the present paper, a fault diagnosis method was proposed based on stationary subspace analysis (SSA and least squares support vector machine (LS-SVM using only a single sensor. First, SSA was used to extract stationary and non-stationary sources from multi-dimensional signals without the need for independency and without prior information of the source signals, after the dimensionality of the vibration signal observed by a single sensor was expanded by phase space reconstruction technique. Subsequently, 10 dimensionless parameters in the time-frequency domain for non-stationary sources were calculated to generate samples to train the LS-SVM. Finally, the measured vibration signals from tools of an unknown state and their non-stationary sources were separated by SSA to serve as test samples for the trained SVM. The experimental validation demonstrated that the proposed method has better diagnosis accuracy than three previous methods based on LS-SVM alone, Principal component analysis and LS-SVM or on SSA and Linear discriminant analysis.

  6. Findings of a Four-Year Randomized Controlled Clinical Trial Comparing Two-Piece and One-Piece Zirconia Abutments Supporting Single Prosthetic Restorations in Maxillary Anterior Region.

    Science.gov (United States)

    Paolantoni, Guerino; Marenzi, Gaetano; Blasi, Andrea; Mignogna, Jolanda; Sammartino, Gilberto

    2016-01-01

    The purpose of this randomized controlled study is to investigate the clinical results obtained over four years and incidence of complications associated with one- versus two-piece custom made zirconia anchorages, in single tooth implant-supported restorations of the maxillary anterior region. Sixty-five patients, with a total of 74 missing maxillary teeth, were selected in the period from February 2007 to July 2010. Two different ways of custom made zirconia abutment and final prosthetic restoration were evaluated: a standard zirconia abutment associated with a pressed layer of lithium disilicate with an all-ceramic cemented restoration versus one-piece restoration with the facing porcelain fired and pressed straight to the custom made zirconia abutment. In 29 cases, the restoration consisted of an all-ceramic restoration for cementation (two pieces); in 45 cases the restoration was a screw-retained restoration (one piece). Three all-ceramic restorations broke during the observation time. Two one-piece restorations fractured after 26 months. At follow-up examination there were no significant differences between one-piece and two-piece groups regarding the PI, BI, and MBL. Awaiting studies with longer follow-up times, a careful conclusion is that zirconia anchorages for single-implant restorations seem to demonstrate good short-term technical and biological results.

  7. Radiation-induced traslocations in spermatogonia. I

    International Nuclear Information System (INIS)

    Brewen, G.; Preston, R.J.; Luippold, H.E.

    1979-01-01

    In an attempt to further study the influence of low dose rates on translocation frequency, with an emphasis on possible increases at very low dose rates, the authors carried out an experiment over a dose rate range of 1-0.001 R/min, with 2, 3 or 4 doses at each dose rate. Adult male CD1 mice (Charles River Breeding Farms) which were 8-10 weeks old at the start of the irradiations were used throughout the experiment, with the exception of a few animals which were about 40 weeks old and served as an aged control. (Auth.)

  8. Doxorubicin and vincristine affect undifferentiated rat spermatogonia

    NARCIS (Netherlands)

    Beaud, Hermance; van Pelt, Ans; Delbes, Geraldine

    2017-01-01

    Anticancer drugs, such as alkylating agents, can affect male fertility by targeting the DNA of proliferative spermatogonial stem cells (SSC). Therefore, to reduce such side effects, other chemotherapeutics are used. However, less is known about their potential genotoxicity on SSC. Moreover, DNA

  9. Short (8-mm) locking-taper implants supporting single crowns in posterior region: a prospective clinical study with 1-to 10-years of follow-up.

    Science.gov (United States)

    Mangano, Francesco Guido; Shibli, Jamil Awad; Sammons, Rachel Lilian; Iaculli, Flavia; Piattelli, Adriano; Mangano, Carlo

    2014-08-01

    The aim of this study was to evaluate the long-term outcome of short (8-mm) locking-taper implants supporting single crowns in the posterior regions and to analyze the influence of different factors on implant survival and implant-crown success rates. Between June 2002 and September 2011, all patients referred to two private practices for treatment with short (8-mm) implants supporting single tooth restorations in posterior areas of both jaws were considered for inclusion in this study. At each annual follow-up session, clinical and radiographic parameters were assessed. Implant-crown success criteria included absence of pain, suppuration, mobility, and peri-implant radiolucency, distance between the implant shoulder and the first visible bone-to-implant contact (DIB) implant-crown success were assessed using the Kaplan-Meier survival estimator; Chi-square test was applied to evaluate correlations between the study variables. The statistical analysis was performed at the patient and at the implant level. Two hundred and fifteen implants (124 maxilla; 91 mandible) were placed in 194 patients (104 men; 90 women). Three implants failed (2 maxilla; 1 mandible). The 10-year cumulative survival rate was 98.4% (patient-based) and 98.5% (implant-based). Among the surviving implants, the mean DIB was 0.31 (±0.24), 0.43 (±0.29), and 0.62 (±0.31) mm at the 1-, 5-, and 10-year follow-up session; two biologic and three prosthetic complications were reported, for a 10-year cumulative implant-crown success rate of 95.8% (patient-based) and 95.9% (implant-based). The implant survival and implant-crown success rates did not differ significantly with respect to patients' gender, age, smoking habit, parafunctional habit, implant location, implant diameter, and bone type. The use of short (8-mm) locking-taper implants is a predictable treatment modality for the restoration of single tooth gaps of posterior segments of dentition. © 2013 John Wiley & Sons A/S. Published by John

  10. Tuning the properties of metal–organic framework nodes as supports of single-site iridium catalysts: node modification by atomic layer deposition of aluminium

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Dong [Department of Chemical Engineering; University of California; Davis; USA; Momeni, Mohammad R. [Department of Chemistry; Chemical Theory Center; Supercomputing Institute; University of Minnesota; Minneapolis; Demir, Hakan [Department of Chemistry; Chemical Theory Center; Supercomputing Institute; University of Minnesota; Minneapolis; Pahls, Dale R. [Department of Chemistry; Chemical Theory Center; Supercomputing Institute; University of Minnesota; Minneapolis; Rimoldi, Martino [Department of Chemistry; Northwestern University; Evanston; USA; Wang, Timothy C. [Department of Chemistry; Northwestern University; Evanston; USA; Farha, Omar K. [Department of Chemistry; Northwestern University; Evanston; USA; Department of Chemistry; Hupp, Joseph T. [Department of Chemistry; Northwestern University; Evanston; USA; Cramer, Christopher J. [Department of Chemistry; Chemical Theory Center; Supercomputing Institute; University of Minnesota; Minneapolis; Gates, Bruce C. [Department of Chemical Engineering; University of California; Davis; USA; Gagliardi, Laura [Department of Chemistry; Chemical Theory Center; Supercomputing Institute; University of Minnesota; Minneapolis

    2017-01-01

    The metal–organic framework NU-1000, with Zr6-oxo, hydroxo, and aqua nodes, was modified by incorporation of hydroxylated Al(iii) ions by ALD-like chemistry with [Al(CH3)2(iso-propoxide)]2followed by steam (ALD = atomic layer deposition). Al ions were installed to the extent of approximately 7 per node. Single-site iridium diethylene complexes were anchored to the nodes of the modified and unmodified MOFs by reaction with Ir(C2H4)2(acac) (acac = acetylacetonate) and converted to Ir(CO)2complexes by treatment with CO. Infrared spectra of these supported complexes show that incorporation of Al weakened the electron donor tendency of the MOF. Correspondingly, the catalytic activity of the initial supported iridium complexes for ethylene hydrogenation increased, as did the selectivity for ethylene dimerization. The results of density functional theory calculations with a simplified model of the nodes incorporating Al(iii) ions are in qualitative agreement with some catalyst performance data.

  11. A 3-year prospective study of implant-supported, single-tooth restorations of all-ceramic and metal-ceramic materials in patients with tooth agenesis.

    Science.gov (United States)

    Hosseini, Mandana; Worsaae, Nils; Schiødt, Morten; Gotfredsen, Klaus

    2013-10-01

    The purpose of this clinical study was to describe outcome variables of all-ceramic and metal-ceramic implant-supported, single-tooth restorations. A total of 59 patients (mean age: 27.9 years) with tooth agenesis and treated with 98 implant-supported single-tooth restorations were included in this study. Two patients did not attend baseline examination, but all patients were followed for 3 years. The implants supported 52 zirconia, 21 titanium and 25 gold alloy abutments, which retained 64 all-ceramic and 34 metal-ceramic crowns. At baseline and 3-year follow-up examinations, the biological outcome variables such as survival rate of implants, marginal bone level, modified Plaque Index (mPlI), modified Sulcus Bleeding Index (mBI) and biological complications were registered. The technical outcome variables included abutment and crown survival rate, marginal adaptation of crowns, cement excess and technical complications. The aesthetic outcome was assessed by using the Copenhagen Index Score, and the patient-reported outcomes were recorded using the OHIP-49 questionnaire. The statistical analyses were mainly performed by using mixed model of ANOVA for quantitative data and PROC NLMIXED for ordinal categorical data. The 3-year survival rate was 100% for implants and 97% for abutments and crowns. Significantly more marginal bone loss was registered at gold-alloy compared to zirconia abutments (P = 0.040). The mPlI and mBI were not significantly different at three abutment materials. The frequency of biological complications was higher at restorations with all-ceramic restorations than metal-ceramic crowns. Loss of retention, which was only observed at metal-ceramic crowns, was the most frequent technical complication, and the marginal adaptations of all-ceramic crowns were significantly less optimal than metal-ceramic crowns (P = 0.020). The professional-reported aesthetic outcome demonstrated significantly superior colour match of all-ceramic over metal

  12. Effects of single dose GnRH agonist as luteal support on pregnancy outcome in frozen-thawed embryo transfer cycles: an RCT

    Directory of Open Access Journals (Sweden)

    Robab Davar

    2015-08-01

    Full Text Available Background: There is no doubt that luteal phase support is essential to enhance the reproductive outcome in IVF cycles. In addition to progesterone and human chorionic gonadotropin, several studies have described GnRH agonists as luteal phase support to improve implantation rate, pregnancy rate and live birth rate, whereas other studies showed dissimilar conclusions. All of these studies have been done in fresh IVF cycles. Objective: To determine whether an additional GnRH agonist administered at the time of implantation for luteal phase support in frozen-thawed embryo transfer (FET improves the embryo developmental potential. Materials and Methods: This is a prospective controlled trial study in 200 FET cycles, patients were randomized on the day of embryo transfer into group 1 (n=100 to whom a single dose of GnRH agonist (0.1 mg triptorelin was administered three days after transfer and group 2 (n=100, who did not receive agonist. Both groups received daily vaginal progesterone suppositories plus estradiol valerate 6 mg daily. Primary outcome measure was clinical pregnancy rate. Secondary outcome measures were implantation rate, chemical, ongoing pregnancy rate and abortion rate. Results: A total of 200 FET cycles were analyzed. Demographic data and embryo quality were comparable between two groups. No statistically significant difference in clinical and ongoing pregnancy rates was observed between the two groups (26% versus 21%, p=0.40 and 21% versus 17%, p=0.37, respectively. Conclusion: Administration of a subcutaneous GnRH agonist at the time of implantation does not increase clinical or ongoing pregnancy.

  13. Supportive text messages for patients with alcohol use disorder and a comorbid depression: a protocol for a single-blind randomised controlled aftercare trial.

    Science.gov (United States)

    Hartnett, Dan; Murphy, Edel; Kehoe, Elizabeth; Agyapong, Vincent; McLoughlin, Declan M; Farren, Conor

    2017-05-29

    Alcohol use disorders (AUDs) and mood disorders commonly co-occur, and are associated with a range of negative outcomes for patients. Mobile phone technology has the potential to provide personalised support for such patients and potentially improve outcomes in this difficult-to-treat cohort. The aim of this study is to examine whether receiving supporting SMS text messages, following discharge from an inpatient dual diagnosis treatment programme, has a positive impact on mood and alcohol abstinence in patients with an AUD and a comorbid mood disorder. The present study is a single-blind randomised controlled trial. Patients aged 18-70 years who meet the criteria for both alcohol dependency syndrome/alcohol abuse and either major depressive disorder or bipolar disorder according to the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders IV Axis I will be randomised to receive twice-daily supportive SMS text messages for 6 months plus treatment as usual, or treatment as usual alone, and will be followed-up at 3, 6, 9 and 12 months postdischarge. Primary outcome measures will include changes from baseline in cumulative abstinence duration, which will be expressed as the proportion of days abstinent from alcohol in the preceding 90 days, and changes from baseline in Beck Depression Inventory scores. The trial has received full ethical approval from the St. Patrick's Hospital Research Ethics Committee (protocol 13/14). Results of the trial will be disseminated through peer-reviewed journal articles and at academic conferences. NCT02404662; Pre-results. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  14. Clinical Results and Technical Complications of Posterior Implant-Supported Modified Monolithic Zirconia Single Crowns and Short-Span Fixed Dental Prostheses: A 2-Year Pilot Study.

    Science.gov (United States)

    Cheng, Chih-Wen; Chien, Chia-Hui; Chen, Chun-Jung; Papaspyridakos, Panos

    2018-02-01

    The purpose of this clinical trial was to investigate the clinical outcomes of implant-supported modified monolithic zirconia single crowns (SCs) and short-span fixed dental prostheses (FDPs) after a follow-up of 2 years. Twenty-seven patients in need of implant-supported SCs or 3-unit FDPs in the posterior maxilla or mandible were consecutively selected for this study. A total of 56 modified monolithic zirconia prostheses including 44 SCs (8 screw-retained, 36 cement-retained) and twelve 3-unit FDPs (5 screw-retained, 7 cement-retained) were included in this study. All patients were followed at 6 months, 12 months, 18 months, and 2 years after placement of the modified monolithic zirconia prostheses. During the follow-up period, all prostheses were evaluated with clinical and radiographic examinations. The following technical parameters were assessed: framework fracture, fracture of veneering porcelain, screw loosening, loss of retention because of prosthesis de-cementation and opposing tooth fracture. No implant was lost during the follow-up period, yielding a 2-year implant survival of 100%. One FDP failed because of framework fracture. The overall prosthesis survival rate was 98.2% after 2 years of clinical service. During the study, 5 complication events were observed in 3 SCs and one FDP, including one fracture of veneering porcelain and 2 screw loosenings in 3 SCs, and loss of retention and opposing tooth fracture in the same FDP. Therefore, the complication-free rate of prostheses was 91.1%. According to the results of this study, the modified monolithic zirconia design used in this study resulted in a favorable short-term outcome for posterior implant-supported SCs and 3-unit FDPs. © 2017 by the American College of Prosthodontists.

  15. Eleven-Year Follow-Up of a Prospective Study of Zirconia Implant Abutments Supporting Single All-Ceramic Crowns in Anterior and Premolar Regions.

    Science.gov (United States)

    Zembic, Anja; Philipp, Alexander Otto Hermann; Hämmerle, Christoph Hans Franz; Wohlwend, Arnold; Sailer, Irena

    2015-10-01

    Clinical studies on zirconia abutments report very good survival rates and biological and technical results, but few have an observation period of more than 5 years. The aim of this study was to assess the long-term performance of customized zirconia implant abutments supporting all-ceramic crowns. Twenty-seven patients receiving 54 single implants were included (25 incisors, 14 canines, 15 premolars in both jaws). Yttria-stabilized zirconia abutments were screwed to the implants with a defined torque. All-ceramic crowns were adhesively cemented onto the abutments. The implants, abutments, and crowns were clinically and radiographically examined after 11 years of use. Modified United States Public Health Service (USPHS) criteria were used to assess technical outcomes: fracture of abutment/crown framework/veneering ceramic, loosening of abutment screw/crown, marginal adaptation, anatomical form, occlusal wear, and abutment fit. The biological parameters were pocket probing depth, plaque control record, bleeding on probing, papilla index, and gingival/mucosal recession at implants and neighboring natural teeth. The cumulative success rate of abutments and crowns was calculated by the Kaplan-Meier method. The results of the USPHS criteria were analyzed descriptively. Sixteen patients with 31 zirconia abutments were examined at 11.3 (±0.9) years after implantation. No abutment or crown was lost. The cumulative success rate was 96.3% for abutments and 90.7% for crowns. Two abutment screws loosened, and three crowns exhibited minor chipping. There were no biological complications. Customized zirconia single implant abutments exhibited excellent long-term outcomes in anterior and premolar regions. © 2014 Wiley Periodicals, Inc.

  16. A single source precursor route to group 13 homo- and heterometallic oxides as highly active supports for gold-catalyzed aerobic epoxidation of trans-stilbene

    KAUST Repository

    Mishra, Shashank K.

    2012-12-14

    A new Mitsubishi-type of star-shaped homoleptic derivative of indium(III), In4(mdea)6 (2, mdeaH2 = N-methyldiethanolamine) , was synthesized by the chloro-aminoalkoxo exchange reaction of a heteroleptic complex In6Cl6(mdea)6 (1) and used as a facile single source molecular precursor for the sol-gel preparation of high surface area indium oxide. Successful deposition of gold nanoparticles (1 wt.-%) of average size 3.3 nm on the above metal oxide by using HAuCl4· 3H2O afforded a highly efficient Au/In2O3 catalyst for the aerobic epoxidation of trans-stilbene at low temperature. The above single source precursor approach was further extended to obtain other group 13 homo- and heterometallic oxides, namely, α-Ga2O 3, β-Ga2O3 and Al4Ga 2O9, as highly active supports for gold catalysts. The obtained Au/M2O3 (M = Ga, In) and Au/Al4Ga 2O9 catalysts were thoroughly characterized by using several physicochemical techniques such as XRD, high resolution transmission electron microscopy (HR-TEM), energy-dispersive X-ray (EDX) spectroscopy, and X-ray photoelectron spectroscopy (XPS). A comparative study of the above catalysts for the model aerobic oxidation of stilbene in methylcyclohexane was undertaken. Highly efficient catalysts for aerobic oxidation reactions were obtained by depositing gold nanoparticles on group 13 mono- or mixed metal oxides prepared from the hydrolysis of well-characterized homo- and heterometallic N-methyldiethanolaminate derivatives. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Narrow- and regular-diameter implants in the posterior region of the jaws to support single crowns: A 3-year split-mouth randomized clinical trial.

    Science.gov (United States)

    de Souza, André Barbisan; Sukekava, Flávia; Tolentino, Livia; César-Neto, João Batista; Garcez-Filho, João; Araújo, Mauricio G

    2018-01-01

    The objective of this 3-year split-mouth randomized controlled clinical study was to compare narrow-diameter implants (NDIs) to regular-diameter implants (RDIs) in the posterior region of the jaws (premolars and molars) in regards to (i) the marginal bone level (MBL) and (ii) implant and prosthesis survival and success rates. A total of 22 patients were included in the study. Each patient received at least one implant of each diameter (Ø3.3 and Ø4.1 mm), placed either in the maxilla or mandible to support single crowns. A total 44 implants (22 NDIs and 22 RDIs) were placed and included in the study. Twenty-one implants were placed in the premolar, whereas 23 were placed in molar areas. Radiographic evaluations to access the MBL were performed immediately after implant placement, 1 and 3 years after implant loading. Peri-implant clinical variables including probing pocket depth (PPD) and bleeding on probing (BoP) were obtained after crown delivery, 1 and 3 years after loading. Furthermore, the survival and success rates of the implants and prosthesis were also evaluated. Twenty patients were able to complete the study. There was no statistically significant difference regarding MBL between groups at implant placement (p = .084), 1-year (p = .794) and 3-year (p = .598) time intervals. The mean peri-implant bone loss at 3-year follow-up was -0.58 ± 0.39 mm (95% CI: -0.751 to -0.409) and -0.53 ± 0.46 mm (95% CI: -0.731 to -0.329) for NDIs and RDIs, respectively. BoP was present at 15% and 10% of NDIs and RDIs, respectively, at 3-year follow-up. PPD >5 mm was observed in 5% and 0% of the implants of NDIs and RDIs, respectively, at 3-year follow-up. At the 3-year examination, the implant success rates were in the NDIs and RDIs sites, respectively, 95% and 100%. The corresponding values for prosthesis success rates were 90% for NDIs and 95% for RDIs. The present study demonstrated that NDIs placed to support single crowns in the posterior region did

  18. Risk factors for single crowns supported by short (6-mm) implants in the posterior region: A prospective clinical and radiographic study.

    Science.gov (United States)

    Villarinho, Eduardo Aydos; Triches, Diego Fernandes; Alonso, Fernando Rizzo; Mezzomo, Luis André Mendonça; Teixeira, Eduardo Rolim; Shinkai, Rosemary Sadami Arai

    2017-08-01

    The use of short implants is still not a consensus for challenging clinical situations, such as unfavorable crown-to-implant (C/I) ratio. This prospective study evaluated the rates of prosthetic complications and implant failure, the mean marginal bone loss of 6-mm dental implants with single crowns in posterior regions and the potential risk factors. Forty-six dental implants, 6-mm long and 4.1-mm wide, were placed in the posterior region in 20 patients. Patients were clinically and radiographically examined after the restoration with single crowns and on a yearly basis. Potential risk factors (arch, bruxism, maximum bite force, anatomical and clinical C/I ratios, and occlusal table area) were analyzed according to the following outcomes: implant survival, bone loss, and prosthetic complications. The mean follow-up time was 45 ± 9 (16-57) months. There was no early loss of implants. After prosthetic loading, 4 implants were lost (2 in the mandible and 2 in the maxilla; 91.3% survival), and there were 13 prosthetic complications (28.3%), yielding a 65.2% success rate. The frailty term showed a 95% greater chance of loss in the mandible than the maxilla. Mean peri-implant bone loss was of 0.2 ± 0.4 mm, 0.1 ± 0.2 mm, 0.1 ± 0.3 mm, and 0.2 ± 0.4 mm in the first, second, third, and fourth years, respectively, with a mean cumulative loss of 0.3 ± 0.5 mm at 48 months. In the multilevel model, the effects of the clinical C/I ratio and time were significant for bone loss (P implants supporting single crowns performed well, but the mandible shows a higher risk of failure. The time and clinical C/I ratio are predictors for bone loss. © 2017 Wiley Periodicals, Inc.

  19. The Up-to-14-Year Survival and Complication Burden of 256 TiUnite Implants Supporting One-Piece Cast Abutment/Metal-Ceramic Implant-Supported Single Crowns.

    Science.gov (United States)

    Walton, Terry R

    To assess the estimated cumulative survival (ECS) and explore the technical and biologic complications of 256 TiUnite implants (Nobel Biocare) supporting one-piece cast abutment/metal-ceramic implant-supported single crowns (ISCs) in situ for up to 14 years. A prospective sequentially recruited cohort of 207 patients received 256 metal-ceramic ISCs on TiUnite implants between 2001 and 2014. All but 24 patients with 27 crowns were clinically evaluated between January 2014 and April 2015 in conjunction with or in addition to their tailored maintenance program. Radiographs were obtained, and any previously recorded treatments associated with the crowns were tabulated. The ECS and standard errors were calculated with the life table actuarial method and Greenwood's formula, respectively. The log rank test was applied to assess differences between anterior and posterior crowns. Complication incidence, severity, and economic burden, measured in time/cost accounting units (TAUs), were tallied and compared descriptively. Independent groups were compared with the Mann-Whitney U test and related groups with the Wilcoxon Signed Rank Test. The mean clinical service time of the crowns was 5.61 years (44 ≥ 10 years). The 14-year ECS was 95.95% ± 3.20% with no significant difference between anterior and posterior prostheses. Only seven implants lost marginal bone ≥ one thread from the time of crown insertion. There were 30 nonterminal complications (16 biologic, 14 mechanical). The associated economic burden was low (n = 35 TAUs). High gold-alloy one-piece cast abutment/metal-ceramic ISCs on TiUnite implants exhibited excellent longevity and few complications over 14 years.

  20. DFT + U investigation on the adsorption and initial decomposition of methylamine by a Pt single-atom catalyst supported on rutile (110) TiO{sub 2}

    Energy Technology Data Exchange (ETDEWEB)

    Lv, Cun-Qin [College of Chemistry and Environmental Engineering, Shanxi Datong University, Datong 037009, Shanxi Province (China); Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), Nankai University, Tianjin 300071 (China); Liu, Jian-Hong, E-mail: ljh173@126.com [College of Chemistry and Environmental Engineering, Shanxi Datong University, Datong 037009, Shanxi Province (China); Guo, Yong; Li, Xue-Mei [College of Chemistry and Environmental Engineering, Shanxi Datong University, Datong 037009, Shanxi Province (China); Wang, Gui-Chang, E-mail: wangguichang@nankai.edu.cn [Department of Chemistry, Tianjin Key Lab. of Metal and Molecule-Based Material Chemistry, Nankai University, Tianjin 300071 (China)

    2016-12-15

    Highlights: • DFT + U is used to investigate the initial decomposition of methylamine. • The adsorption characteristics of possible intermediates involved in methylamine initial decomposition are discussed. • The energy barriers of the possible elementary reactions involved are obtained. • C−H bond scission is the most favored among the C−H, N−H and C−N bond breakings in methylamine. - Abstract: The adsorption and initial decomposition for methylamine catalyzed by a single Pt atom supported on rutile (110) titania (namely, Pt{sub 1}/TiO{sub 2}–R(110)) surface have been investigated by the density functional theory slab calculations with Hubbard corrections (DFT + U). The main purpose of the work is to better understand the role of dispersed platinum metal on the surface of rutile (110) titania in the initial decomposition of methylamine. Our calculated results show that the barriers increased with the order of C−H < N−H < C−N, which indicates that the C−H bond is the easiest to decompose and the C−N bond is the most difficult to break.

  1. Comparison of forward versus backward walking using body weight supported treadmill training in an individual with a spinal cord injury: a single subject design.

    Science.gov (United States)

    Moriello, Gabriele; Pathare, Neeti; Cirone, Cono; Pastore, Danielle; Shears, Dacia; Sulehri, Sahira

    2014-01-01

    Body weight supported treadmill training (BWSTT) is a task-specific intervention that promotes functional locomotion. There is no research evaluating the effect of backward walking (BW) using BWSTT in individuals with spinal cord injury (SCI). The purpose of this single subject design was to examine the differences between forward walking (FW) and BW training using BWSTT in an individual with quadriparesis. The participant was a 57-year-old male with incomplete C3-C6 SCI. An ABABAB design (A = BW; B = FW; each phase = 3 weeks of biweekly sessions) was utilized. Outcome measures included: gait parameters; a timed 4-meter walk; the 5-repetition sit-to-stand test (STST); tandem stance time; and 6-minute walk test (6MWT). Data was analyzed with split level method of trend estimation. Improvements in gait parameters, on the timed 4-meter walk, 6MWT, tandem balance and aerobic endurance were similar with FW and BW training. The only difference between FW and BW training was that BW training resulted in greater improvements in the STST. The results of this study suggest that in this individual backward walking training was advantageous, resulting in improved ability to perform the 5-repetition STST. It is suspected that these changes can be attributed to the differences in muscle activation and task difficulty between FW and BW.

  2. IMPROVED EX-TANK LEAK DETECTION and MONITORING TECHNOLOGY DEMONSTRATIONS IN SUPPORT OF SINGLE SHELL TANK (SST) WASTE RETRIEVAL AT HANFORD SITE

    International Nuclear Information System (INIS)

    ROGER, R.M.; CAMMANN, J.W.

    2002-01-01

    Led by the United States Department of Energy Office of River Protection (DOE-ORP) and CH2M HILL Hanford Group, Inc. (CHG), a team of experts from other facilities have been working together to narrow the field of new external tank leak detection technologies. The ability to detect and assess potential leaks more quickly will help reduce potential risks to public health and the environment during efforts to retrieve millions of gallons of waste from Hanford's older single-shell tanks (SST's). A method for early and reliable detection of leaks around and below the entire 75-foot diameter bottom of a SST is needed. ''Proof-of-concept'' testing of six ex-tank leak detection and monitoring technologies was conducted at Hanford's 105-A Mock Tank Site in August 2001. A workshop was conducted in January, 2002 to review the results and select the best of the methods tested for further testing and demonstration in support of an SST retrieval. Three methods were selected: High Resolution Resistivity; Electrical Resistance Tomography--Long Electrodes; and Electrical Resistance Tomography--Point Electrode Arrays. Planned development activity includes performance evaluation tests to determine probability of detection and the probability of false alarm for each technology and deployability tests in an actual Hanford tank farm environment

  3. A Polymer Encapsulation Strategy to Synthesize Porous Nitrogen-Doped Carbon-Nanosphere-Supported Metal Isolated-Single-Atomic-Site Catalysts.

    Science.gov (United States)

    Han, Aijuan; Chen, Wenxing; Zhang, Shaolong; Zhang, Maolin; Han, Yunhu; Zhang, Jian; Ji, Shufang; Zheng, Lirong; Wang, Yu; Gu, Lin; Chen, Chen; Peng, Qing; Wang, Dingsheng; Li, Yadong

    2018-03-06

    A novel polymer encapsulation strategy to synthesize metal isolated-single-atomic-site (ISAS) catalysts supported by porous nitrogen-doped carbon nanospheres is reported. First, metal precursors are encapsulated in situ by polymers through polymerization; then, metal ISASs are created within the polymer-derived p-CN nanospheres by controlled pyrolysis at high temperature (200-900 °C). Transmission electron microscopy and N 2 sorption results reveal this material to exhibit a nanospheric morphology, a high surface area (≈380 m 2 g -1 ), and a porous structure (with micropores and mesopores). Characterization by aberration-corrected high-angle annular dark-field scanning transmission electron microscopy and X-ray absorption fine structure confirms the metal to be present as metal ISASs. This methodology is applicable to both noble and nonprecious metals (M-ISAS/p-CN, M = Co, Ni, Cu, Mn, Pd, etc.). In particular, the Co-ISAS/p-CN nanospheres obtained using this method show comparable (E 1/2 = 0.838 V) electrochemical oxygen reduction activity to commercial Pt/C with 20 wt% Pt loading (E 1/2 = 0.834 V) in alkaline media, superior methanol tolerance, and outstanding stability, even after 5000 cycles. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Uranium tris-aryloxide derivatives supported by triazacyclononane: engendering a reactive uranium(III) center with a single pocket for reactivity.

    Science.gov (United States)

    Castro-Rodriguez, Ingrid; Olsen, Kristian; Gantzel, Peter; Meyer, Karsten

    2003-04-16

    The synthesis and spectroscopic characterization of the mononuclear uranium complex [((ArO)(3)tacn)U(III)(NCCH(3))] is reported. The uranium(III) complex reacts with organic azides to yield uranium(IV) azido as well as uranium(V) imido complexes, [((ArO)(3)tacn)U(IV)(N(3))] and [((ArO)(3)tacn)U(V)(NSi(CH(3))(3))]. Single-crystal X-ray diffraction, spectroscopic, and computational studies of this analogous series of uranium tris-aryloxide complexes supported by triazacyclononane are described. The hexadentate, tris-anionic ligand coordinates to the large uranium ion in unprecedented fashion, engendering coordinatively unsaturated and highly reactive uranium centers. The macrocyclic triazacyclononane tris-aryloxide derivative occupies six coordination sites, with the three aryloxide pendant arms forming a trigonal plane at the metal center. DFT quantum mechanic methods were applied to rationalize the reactivity and to elucidate the electronic structure of the newly synthesized compounds. It is shown that the deeply colored uranium(III) and uranium(V) species are stabilized via pi-bonding interaction, involving uranium f-orbitals and the axial acetonitrile and imido ligand, respectively. In contrast, the bonding in the colorless uranium(IV) azido complex is purely ionic in nature. The magnetism of the series of complexes with an [N3O3-N(ax)] core structure and oxidation states +III, +IV, and +V is discussed in context of the electronic structures.

  5. MedTech Mag-Lev, single-use, extracorporeal magnetically levitated centrifugal blood pump for mid-term circulatory support.

    Science.gov (United States)

    Nagaoka, Eiki; Fujiwara, Tatsuki; Kitao, Takashi; Sakota, Daisuke; Shinshi, Tadahiko; Arai, Hirokuni; Takatani, Setsuo

    2013-01-01

    Short- to mid-term extracorporeal ventricular assist devices (VADs) are recommended for critical cardiogenic shock patients. We have designed a preclinical, single-use MedTech Mag-Lev VAD for one-month extracorporeal use. The impeller-rotor of the pump was suspended by a two degree-of-freedom active magnetic bearing in a 300 μm fluid gap, where the computational fluid dynamics analysis predicted a secondary flow of about 400-500 ml/min at a pump speed of 1800-2200 rpm. Three eddy current sensors were employed to implement noise- and drift-free magnetic levitation. The pump components were injection molded using polycarbonate for smooth surfaces as well as improved reproducibility, followed by coating with a biocompatible 2-methacryloyl-oxyethyl phosphorylcholine polymer. Chronic animal experiments were performed in nine calves. Three of the nine calves were excluded from analysis for problems with the circuit. Five of the six (83.3%) completed the 60 day duration of the study, while one prematurely died of massive bleeding due to inflow port detachment. The pump did not stop due to magnetic-levitation malfunction. Neither pump thrombosis nor major organ infarction was observed at autopsy. In comparison to machined surfaces, the injection-molded pump surfaces were thrombus-free after 60 day implantation. This study demonstrates the feasibility of MedTech Mag-Lev VAD for 60 day circulatory support.

  6. All-ceramic or metal-ceramic tooth-supported fixed dental prostheses (FDPs)? A systematic review of the survival and complication rates. Part I: Single crowns (SCs).

    Science.gov (United States)

    Sailer, Irena; Makarov, Nikolay Alexandrovich; Thoma, Daniel Stefan; Zwahlen, Marcel; Pjetursson, Bjarni Elvar

    2015-06-01

    To assess the 5-year survival of metal-ceramic and all-ceramic tooth-supported single crowns (SCs) and to describe the incidence of biological, technical and esthetic complications. Medline (PubMed), Embase, Cochrane Central Register of Controlled Trials (CENTRAL) searches (2006-2013) were performed for clinical studies focusing on tooth-supported fixed dental prostheses (FDPs) with a mean follow-up of at least 3 years. This was complimented by an additional hand search and the inclusion of 34 studies from a previous systematic review [1,2]. Survival and complication rates were analyzed using robust Poisson's regression models to obtain summary estimates of 5-year proportions. Sixty-seven studies reporting on 4663 metal-ceramic and 9434 all-ceramic SCs fulfilled the inclusion criteria. Seventeen studies reported on metal-ceramic crowns, and 54 studies reported on all-ceramic crowns. Meta-analysis of the included studies indicated an estimated survival rate of metal-ceramic SCs of 94.7% (95% CI: 94.1-96.9%) after 5 years. This was similar to the estimated 5-year survival rate of leucit or lithium-disilicate reinforced glass ceramic SCs (96.6%; 95% CI: 94.9-96.7%), of glass infiltrated alumina SCs (94.6%; 95% CI: 92.7-96%) and densely sintered alumina and zirconia SCs (96%; 95% CI: 93.8-97.5%; 92.1%; 95% CI: 82.8-95.6%). In contrast, the 5-year survival rates of feldspathic/silica-based ceramic crowns were lower (pcrowns exhibited significantly lower survival rates in the posterior region (pcrown types performed similarly. Densely sintered zirconia SCs were more frequently lost due to veneering ceramic fractures than metal-ceramic SCs (p<0.001), and had significantly more loss of retention (p<0.001). In total higher 5 year rates of framework fracture were reported for the all-ceramic SCs than for metal-ceramic SCs. Survival rates of most types of all-ceramic SCs were similar to those reported for metal-ceramic SCs, both in anterior and posterior regions. Weaker

  7. Single implant-supported crowns in the aesthetic zone: patient satisfaction with aesthetic appearance compared with appraisals by laypeople and dentists.

    Science.gov (United States)

    Fava, Joseph; Lin, Mark; Zahran, Mohammed; Jokstad, Asbjorn

    2015-10-01

    To appraise the patients' satisfaction with aesthetic outcomes following an implant restoration in the anterior maxilla as compared to appraisals made by dentists and laypeople. Randomly selected patients (n = 116) restored with an implant-retained crown in the anterior maxilla were invited to rate their satisfaction with aesthetic outcomes using a questionnaire containing seven criteria, each graded from excellent to poor. Projected images of the patient smiles were appraised by dentists (n = 8) and laypeople (n = 6) using the same assessment criteria in a room setting. In addition, the laypeople judged the same cases on printed 10 × 15 cm photographs in a separate setting. Jemt papilla scores, pink aesthetic score (PES) and white esthetic score (WES) were assigned by the dentists. Differences in the levels of satisfaction between the patient, and appraisals by the dentists and the laypeople were compared using non-parametric statistical tests. Patients' opinions of their aesthetic appearance following the placement of a single implant-supported crown in the aesthetic zone were in general very favourable. The laypeople were more critical than the dentists when the aesthetic outcomes were appraised on magnified images projected onto a screen. Laypeople became less critical when evaluating the aesthetic outcomes on printed photographs compared to appraisals on a screen. Patient satisfaction with their aesthetic appearance differed from dentists' and laypeople's appraisals. Factors other than the actual aesthetic outcome itself appear to influence patients' satisfaction with their end results. Laypeople's appraisal is influenced by the magnification and method used for appraising the aesthetic outcomes. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  8. Performance of zirconia abutments for implant-supported single-tooth crowns in esthetic areas: a retrospective study up to 12-year follow-up.

    Science.gov (United States)

    Passos, Sheila Pestana; Linke, Bernie; Larjava, Hannu; French, David

    2016-01-01

    The aim of this clinical study was to assess complications, success, and survival rates of zirconia abutments from different implant designs. Anterior implant-supported single-tooth restorations, after 1-12 years of clinical function, were evaluated. One hundred and fifty-eight zirconia implant abutments placed in 141 patients were evaluated. Mechanical complications were observed, such as presence or absence of abutment fractures and loss of retention. In addition, the peri-implant parameters were observed. Statistical analysis was performed using Fisher's exact tests, and bone level was analyzed using the nonparametric Mann-Whitney U-test for non-normally distributed data. Sixteen restorations exhibited different complications. However, no significant difference was observed between the standard and platform switching. The standard platforms exhibited higher marginal bone loss than platform switching design followed up to 5 years. Platform switching has a potentially higher risk of fracture in some designs. In our study, one standard platform as well as two-platform switch designs seem to withstand fracture in the anterior area, regardless of the implant width. Survival and success rates were 93.8% and 81.2% (up to >7 years ≤12), respectively, for standard platform; and 90 and 84% (up to >2 years ≤5), respectively, for platform switching. In general, standard platform implants restored with zirconia abutments were successful for the longest periods of observation and are a viable treatment alternative in anterior areas. Some of the studied designs of platform switching implants with zirconia abutments performed well for up to 5 years. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  9. Oral health related quality-of-life outcomes of partially edentulous patients treated with implant-supported single crowns or fixed partial dentures.

    Science.gov (United States)

    AlZarea, Bader K

    2017-05-01

    Oral health-related quality of life (OHRQoL) is afflicted by different variables. Limited information is available regarding the impact of different phases of implant therapy on OHRQoL of edentulous patients. This study was carried out to assess the OHRQoL of patients treated with implant-supported single crowns or fixed partial dentures. A total of 79 healthy partially edentulous subjects needing implant therapy were incorporated in this study. Before placement of the implants, the subjects were instructed to fill the original version of OHIP questionnaire. Subsequently patients received titanium oral implants of the ITI® Dental Implant System. After 1st, 2nd and 3rd year of implant placement, patients filled the same OHIP-49 questionnaire. In this manner the impact of implant therapy on OHRQoL by putting in comparison pre- and post-treatment OHIP-49 scores was assessed. Statistical analyses were performed using Statistical Package for the Social Science software (SPSS, version 22, Chicago, IL, USA). Paired t test and Unpaired t test were performed and a statistical significance was set at 5% level of significance ( p disability, psychological disability, social disability were significantly decreased from baseline to 1st year ( p 0.05). All variables were also significantly decreased from baseline to 2nd year and 3rd year ( p 0.05). Patients aged less than 60 years and more than 60 years of age groups differed significantly with respect to OHIP scores measured at 1st year, 2nd year and at 3rd year of implant placement ( p Oral health-related quality-of-life.

  10. Single crowns in the resorbed posterior maxilla supported by either 6-mm implants or by 11-mm implants combined with sinus floor elevation surgery : A 1-year randomised controlled trial

    NARCIS (Netherlands)

    Guljé, Felix L; Raghoebar, Gerry M; Vissink, Arjan; Meijer, Henny J A

    2014-01-01

    Purpose: The aim of this randomised controlled trial was to assess the clinical performance of single crowns in the posterior maxilla supported by either 6-mm or 11-mm implants combined with maxillary sinus floor elevation. Materials and methods: 41 consecutive patients with one missing premolar or

  11. Impact of Crown-Implant Ratio of Single Restorations Supported by 6-mm Implants : A Short-Term Case Series Study

    NARCIS (Netherlands)

    Gulje, Felix L.; Raghoebar, Gerry M.; Erkens, Ward A. L.; Meijer, Henny J. A.

    PURPOSE: High crown-implant ratios might affect the biologic and technical performance of a reconstruction. The aim of this study was to assess whether a higher crown-implant ratio of single restorations on 6-mm implants resulted in more peri-implant bone loss and more prosthetic complications

  12. Analysis of crestal bone loss around single piece ball attachment implant placed bilaterally in canine region and wear of O-ring in implant supported overdenture: Three year follow-up.

    Science.gov (United States)

    Raza, Fathima Banu; Vaidyanathan, Anand Kumar; Veeravalli, Padmanabhan T; Ravishankar, Subhiksha; Ali, Aashique S

    2018-03-06

    Single piece implant in fixed prosthesis is widely been evaluated, however, long term evaluation of crestal bone loss and the wear of O-ring in single piece ball attachment implant supported overdenture is yet to be evaluated PURPOSE: The present article evaluates the crestal bone loss around single piece ball attachment implants placed bilaterally in the canine region and the wear of O-ring in implant supported overdenture over a period of three years. Twelve completely edentulous patients between the age group of 55-65 years were selected. Two 3.3 mm × 13 mm myriad snap fit implants were placed in the mandibular interforaminal region. All the implants were conventionally loaded at three months after surgical placement. Intra-oral periapical radiographs were made and crestal bone loss was measured at the end of one year and three years. The elasticity and wear of O-Ring was assessed after three years of usage. The crestal bone loss showed no significant difference between the first and third year after implant placement. The mean bone loss at the end of third year was 1.5 mm. Analysis of O-ring for change in the elasticity showed reduction in displacement and a significant increase in maximum displacement and elongation. The area of O-ring and yield stress did not show any changes from the standard value. Compression set damage was observed in the O-ring at the end of three years. The present study shows that the bilateral single piece implant supported overdenture has a success rate equivalent to the two piece implant supported overdenture and is a viable treatment option. © 2018 Wiley Periodicals, Inc.

  13. Clinical, esthetic, and radiographic evaluation of small-diameter (3.0-mm) implants supporting single crowns in the anterior region: a 3-year prospective study.

    Science.gov (United States)

    Pieri, Francesco; Siroli, Lucia; Forlivesi, Caterina; Corinaldesi, Giuseppe

    2014-01-01

    Fifty patients underwent single-tooth replacement in the maxillary and mandibular incisor area using two-piece 3.0-mm-diameter implants. Clinical and radiographic measurements of soft and hard tissue levels and esthetic parameters (pink esthetic score/white esthetic score [PES/WES]) were assessed at 3 years. No implant failed (success rate: 100%), and facial soft tissues and marginal bone levels remained stable throughout the study period. The mean total PES/WES was high (14.1 ± 1.75), and only one implant demonstrated an unfavorable esthetic outcome (PES/WES = 10). The use of 3.0-mm-diameter implants appears to be a viable treatment procedure in the medium term for single-tooth anterior restorations with limited dimensions.

  14. Single-blind randomized clinical trial to evaluate clinical and radiological outcomes after one year of immediate versus delayed implant placement supporting full-arch prostheses

    OpenAIRE

    Pellicer-Chover, Hilario; Peñarrocha-Oltra, David; Bagán, Leticia; Fichy-Fernandez, Antonio J.; Canullo, Luigi; Peñarrocha-Diago, Miguel

    2013-01-01

    Purpose: To evaluate and compare peri-implant health, marginal bone loss and success of immediate and delayed implant placement for rehabilitation with full-arch fixed prostheses. Material and Methods: The present study was a prospective, randomized, single-blind, clinical preliminary trial. Patients were randomized into two treatment groups. In Group A implants were placed immediately post-extraction and in Group B six months after extraction. The following control time-points were establish...

  15. Sensory modulation intervention and behaviour support modification for the treatment of severe aggression in Huntington's disease. A single case experimental design.

    Science.gov (United States)

    Fisher, Caroline A; Brown, Anahita

    2017-09-01

    Aggression is common in Huntington's disease. However, at present there are no standard guidelines for managing aggression in Huntington's sufferers due to a lack of empirical research. This paper presents a case study of the treatment of very high levels of aggression with sensory modulation and behaviour support intervention in a Huntington's sufferer. The client exhibited a range of aggressive behaviours, including physical aggression to people, furniture and objects, and verbal aggression. Following an eight week baseline phase, five weeks of sensory modulation intervention were employed. A behaviour support plan was then implemented as an adjunct to the sensory intervention, with aggressive behaviour systematically audited for a further 11 weeks. The results indicate a significant reduction in reported levels of aggression during the combined sensory modulation and behaviour support phase, compared to both the baseline and the sensory modulation therapy alone phases. This case study highlights the efficacy non-pharmacological interventions may have for reducing aggression in HD.

  16. The NOD3 software package: A graphical user interface-supported reduction package for single-dish radio continuum and polarisation observations

    Science.gov (United States)

    Müller, Peter; Krause, Marita; Beck, Rainer; Schmidt, Philip

    2017-10-01

    Context. The venerable NOD2 data reduction software package for single-dish radio continuum observations, which was developed for use at the 100-m Effelsberg radio telescope, has been successfully applied over many decades. Modern computing facilities, however, call for a new design. Aims: We aim to develop an interactive software tool with a graphical user interface for the reduction of single-dish radio continuum maps. We make a special effort to reduce the distortions along the scanning direction (scanning effects) by combining maps scanned in orthogonal directions or dual- or multiple-horn observations that need to be processed in a restoration procedure. The package should also process polarisation data and offer the possibility to include special tasks written by the individual user. Methods: Based on the ideas of the NOD2 package we developed NOD3, which includes all necessary tasks from the raw maps to the final maps in total intensity and linear polarisation. Furthermore, plot routines and several methods for map analysis are available. The NOD3 package is written in Python, which allows the extension of the package via additional tasks. The required data format for the input maps is FITS. Results: The NOD3 package is a sophisticated tool to process and analyse maps from single-dish observations that are affected by scanning effects from clouds, receiver instabilities, or radio-frequency interference. The "basket-weaving" tool combines orthogonally scanned maps into a final map that is almost free of scanning effects. The new restoration tool for dual-beam observations reduces the noise by a factor of about two compared to the NOD2 version. Combining single-dish with interferometer data in the map plane ensures the full recovery of the total flux density. Conclusions: This software package is available under the open source license GPL for free use at other single-dish radio telescopes of the astronomical community. The NOD3 package is designed to be

  17. "Hydro-metathesis" of olefins: A catalytic reaction using a bifunctional single-site tantalum hydride catalyst supported on fibrous silica (KCC-1) nanospheres

    KAUST Repository

    Polshettiwar, Vivek

    2011-02-18

    Tantalizing hydrocarbons: Tantalum hydride supported on fibrous silica nanospheres (KCC-1) catalyzes, in the presence of hydrogen, the direct conversion of olefins into alkanes that have higher and lower numbers of carbon atoms (see scheme). This catalyst shows remarkable catalytic activity and stability, with excellent potential of regeneration. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Production of propylene from 1-butene on highly active "bi-functional single active site" catalyst: Tungsten carbene-hydride supported on alumina

    KAUST Repository

    Mazoyer, Etienne

    2011-12-02

    1-Butene is transformed in a continuous flow reactor over tungsten hydrides precursor W-H/Al2O3, 1, giving a promising yield into propylene at 150 °C and different pressures. Tungsten carbene-hydride single active site operates as a "bi-functional catalyst" through 1-butene isomerization on W-hydride and 1-butene/2-butenes cross-metathesis on W-carbene. This active moiety is generated in situ at the initiation steps by insertion of 1-butene on tungsten hydrides precursor W-H/Al2O3, 1 followed by α-H and β-H abstraction. © 2011 American Chemical Society.

  19. Stabilizing Single Sites on Solid Supports: Robust Grafted Ti(IV)-Calixarene Olefin Epoxidation Catalysts via Surface Polymerization and Cross-Linking

    OpenAIRE

    Guo, Yijun; Solovyov, Andrew; Grosso-Giordano, Nicolás A.; Hwang, Son-Jong; Katz, Alexander

    2016-01-01

    This manuscript develops a surface polymerization and cross-linking approach for the stabilization of single-site catalysts on solid surfaces, which is demonstrated here for grafted Ti(IV)-calixarene Lewis acids on silica. Our approach relies on cationic polymerization that is initiated by an adsorbed B(C_6F_5)_3 and uses styrene as the monomer and diisopropenylbenzene as the cross-linking agent. The mildness of this polymerization method is demonstrated by its lack of blocking micropores and...

  20. A Common Single-Site Pt(II)–O(OH) x – Species Stabilized by Sodium on “Active” and “Inert” Supports Catalyzes the Water-Gas Shift Reaction

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Ming [Department; Liu, Jilei [Department; Lee, Sungsik [X-ray; Zugic, Branko [Department; Huang, Jun [School; Allard, Lawrence F. [Materials; Flytzani-Stephanopoulos, Maria [Department

    2015-03-05

    While it is long known that different types of support oxides have different capabilities to anchor metals and thus tailor the catalytic behavior, it is not always clear whether the support is a mere carrier of the active metal site, itself not participating directly in the reaction pathway. We report that catalytically similar single-atom centric Pt sites are formed by binding to sodium ions through ?O ligands, the ensemble being equally effective on supports as diverse as TiO2, L-zeolites, and mesoporous silica MCM-41. Loading of 0.5 wt.% Pt on all these supports, preserves the Pt in atomic dispersion as Pt(II), the Pt-O(OH)x- species catalyzing the water-gas shift reaction (WGS) from ~120 to 400 oC. Since the effect of support is ?indirect,? these findings pave the way for the use of a variety of earth-abundant supports as carriers of atomically dispersed platinum for application to catalytic fuel-gas processing.

  1. Immediate loading of bimaxillary total fixed prostheses supported by five flapless-placed implants with machined surfaces: A 6-month follow-up prospective single cohort study.

    Science.gov (United States)

    Cannizzaro, Gioacchino; Felice, Pietro; Loi, Ignazio; Viola, Paolo; Ferri, Vittorio; Leone, Michele; Collivasone, Dario; Esposito, Marco

    2016-01-01

    To evaluate the clinical outcome of fully edentulous patients rehabilitated with immediately loaded bimaxillary screw-retained metal-resin prostheses supported by five implants placed flapless: two in the mandible and three in the maxillae. Twenty-five consecutively treated patients were recruited. To be immediately loaded, implants had to be inserted with a minimum torque of 80 Ncm. Outcome measures were prosthesis and implant failures, and complications. Six months after loading no patients dropped out and no prosthesis or implant failed. Two maxillary prostheses were loaded early at 8 weeks because implants were inserted with a torque inferior to 45 Ncm. Three complications occurred in two patients but they were all successfully treated. Six months after loading, immediately loaded bimaxillary cross-arch prostheses can be supported by only two mandibular and three maxillary flapless-placed dental implants. Longer follow-ups of approximately 10 years are needed to understand the prognosis of this treatment modality.

  2. OPeNDAP servers like Hyrax and TDS can easily support common single-sign-on authentication protocols using the Apache httpd and related software; adding support for these protocols to clients can be more challenging

    Science.gov (United States)

    Gallagher, J. H. R.; Potter, N.; Evans, B. J. K.

    2016-12-01

    OPeNDAP, in conjunction with the Australian National University, documented the installation process needed to add authentication to OPeNDAP-enabled data servers (Hyrax, TDS, etc.) and examined 13 OPeNDAP clients to determine how best to add authentication using LDAP, Shibboleth and OAuth2 (we used NASA's URS). We settled on a server configuration (architecture) that uses the Apache web server and a collection of open-source modules to perform the authentication and authorization actions. This is not the only way to accomplish those goals, but using Apache represents a good balance between functionality, leveraging existing work that has been well vetted and includes support for a wide variety of web services, include those that depend on a servlet engine such as tomcat (which both Hyrax and TDS do). Or work shows how LDAP, OAuth2 and Shibboleth can all be accommodated using this readily available software stack. Also important is that the Apache software is very widely used and is fairly robust - extremely important for security software components. In order to make use of a server requiring authentication, clients must support the authentication process. Because HTTP has included authentication for well over a decade, and because HTTP/HTTPS can be used by simply linking programs with a library, both the LDAP and OAuth2/URS authentication schemes have almost universal support within the OPeNDAP client base. The clients, i.e. the HTTP client libraries they employ, understand how to submit the credentials to the correct server when confronted by an HTTP/S Unauthorized (401) response. Interestingly OAuth2 can achieve it's SSO objectives while relying entirely on normative HTTP transport. All 13 of the clients examined worked.The situation with Shibboleth is different. While Shibboleth does use HTTP, it also requires the client to either scrape a web page or support the SAML2.0 ECP profile, which, for programmatic clients, means using SOAP messages. Since working with

  3. Computational Study on M1/POM Single-Atom Catalysts (M = Cu, Zn, Ag, and Au; POM = [PW12O40]3-): Metal-Support Interactions and Catalytic Cycle for Alkene Epoxidation.

    Science.gov (United States)

    Liu, Chun-Guang; Jiang, Meng-Xu; Su, Zhong-Min

    2017-09-05

    Geometrical structures, metal-support interactions, and infrared (IR) spectroscopy of a series of M 1 /POM (M = Cu, Zn, Ag, and Au; POM = [PW 12 O 40 ] 3- ) single-atom catalysts (SACs), and catalytic cycle for alkene epoxidation catalyzed by M 1 /POM SACs were studied using density functional theory (DFT) calculations. The calculations demonstrate that the most probable anchoring sties for the isolated single atoms studied here in the M 1 /POM SACs are the fourfold hollow sites on the surface of POM support. The bonding interaction between single metal atom and surface of POM support comes from the molecular orbitals with a mixture of d atomic orbital of metal and 2p group orbital of surface oxygen atoms of POM cage. The calculated adsorption energy of isolated metal atoms in these M 1 /POM SACs indicates that the early transition metals (Cu and Zn) have high thermal stability. The DFT-derived IR spectra show that the four characteristic peaks of free Keggin-type POM structure split into six because of introduction of isolated metal atom. Compared with other metal atoms, the Zn 1 /POM SAC has the high reactivity for activity of dioxygen molecule, because the dioxygen moiety in Zn 1 /POM SAC displays O 2 - · radical feature with [POM 4- ·Zn 2+ O 2 - ·] 3- configuration. Finally, a catalytic cycle for ethylene epoxidation by O 2 catalyzed by Zn 1 /POM SAC was proposed based on our DFT calculations. Supported noble-metal SACs are among the most important catalysts currently. However, noble metals are expensive and of limited supply. Development of non-noble-metal SACs is of essential importance. Therefore, the reported Zn 1 /POM SAC would be very useful to guide the search for SACs into non-noble metals.

  4. Towards a Decision Support Tool for 3d Visualisation: Application to Selectivity Purpose of Single Object in a 3d City Scene

    Science.gov (United States)

    Neuville, R.; Pouliot, J.; Poux, F.; Hallot, P.; De Rudder, L.; Billen, R.

    2017-10-01

    This paper deals with the establishment of a comprehensive methodological framework that defines 3D visualisation rules and its application in a decision support tool. Whilst the use of 3D models grows in many application fields, their visualisation remains challenging from the point of view of mapping and rendering aspects to be applied to suitability support the decision making process. Indeed, there exists a great number of 3D visualisation techniques but as far as we know, a decision support tool that facilitates the production of an efficient 3D visualisation is still missing. This is why a comprehensive methodological framework is proposed in order to build decision tables for specific data, tasks and contexts. Based on the second-order logic formalism, we define a set of functions and propositions among and between two collections of entities: on one hand static retinal variables (hue, size, shape…) and 3D environment parameters (directional lighting, shadow, haze…) and on the other hand their effect(s) regarding specific visual tasks. It enables to define 3D visualisation rules according to four categories: consequence, compatibility, potential incompatibility and incompatibility. In this paper, the application of the methodological framework is demonstrated for an urban visualisation at high density considering a specific set of entities. On the basis of our analysis and the results of many studies conducted in the 3D semiotics, which refers to the study of symbols and how they relay information, the truth values of propositions are determined. 3D visualisation rules are then extracted for the considered context and set of entities and are presented into a decision table with a colour coding. Finally, the decision table is implemented into a plugin developed with three.js, a cross-browser JavaScript library. The plugin consists of a sidebar and warning windows that help the designer in the use of a set of static retinal variables and 3D environment

  5. Impact of different catalysis supported by oyster shells on the pyrolysis of tyre wastes in a single and a double fixed bed reactor.

    Science.gov (United States)

    Kordoghli, Sana; Khiari, Besma; Paraschiv, Maria; Zagrouba, Fethi; Tazerout, Mohand

    2017-09-01

    The treatment and disposal of tyres from vehicles has long been of considerable environmental importance. Studies have been undertaken to reduce their environmental impact. In this study, an alternative gas was produced from automobile tyre wastes by the means of a controlled pyrolysis. To do so, a novel catalytic system was designed with the aim of increasing the rate of conversion and improving the quality of the pyrolysis products. This work aimed also to reduce the severity of the overall reactions, by using powder catalysts (MgO, Al 2 O 3 , CaCO 3 , and zeolite ZSM-5) uniformly distributed on two layers of oyster shells (OS) particles. The catalyst/tyres mass ratio was kept for all the tests at 1/30. The pyrolysis reactor was maintained at 500°C and the influence of each catalyst and of the number of shell beds (0, 1 or 2), on the yield and composition of the derived products, was examined. The gas yields could contribute by 1.2% of total consumption in Tunisia. Furthermore, some combinations could upgrade the derived gas and made it possible to use it as such or with the minimum of post-treatment. It was found that, with the use of supported catalyst, the gas produced is 45% greater compared to classical thermal pyrolysis. The Heating value of the produced gas was also improved by the use of supported catalysts; it was found 16% greater with the use of Al 2 O 3 /OS compared to non-catalytic pyrolysis. When compared to the gas obtained from only one catalytic supported bed, the sulfur content was reduced by 80% with the use of CaCO 3 /OS on two catalytic beds. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Single-Tooth Replacement Using Dental Implants Supporting All-Ceramic and Metal-Based Reconstructions: Results at 18 Months of Loading.

    Science.gov (United States)

    Bösch, Adrian; Jung, Ronald Ernst; Sailer, Irena; Goran, Benic; Hämmerle, Christoph Hans; Thoma, Daniel Stefan

    The aim of this study was to compare customized zirconia and titanium abutments with respect to survival rates and technical, biologic, and esthetic outcomes. A total of 28 patients with single implants were randomly assigned to 12 customized zirconia (test, AC) and 16 customized titanium (control, MC) abutments. Technical, biologic, and esthetic outcomes were assessed after a mean follow-up time of 18 months. No biologic complications were observed, and no statistical difference for the bone-to-implant distance was found at 18 months (AC -0.05 ± 0.51 mm vs MC -0.28 ± 0.77 mm; P = .40). A similar discoloration of the peri-implant mucosa was observed (ΔE AC 9.6 ± 5.4, ΔE MC 7.6 ± 5.3; P = .46). The mean papilla score values evaluation presented no statistically significant differences between the test and control groups (AC 2.07 ± 0.94, MC 1.96 ± 0.84). At 18 months, reconstructions based on zirconia and titanium abutments exhibited similar survival rates and similar clinical outcomes.

  7. Single Site Silica Supported Tetramethyl Niobium by the SOMC Strategy: Synthesis, Characterization and Structure-Activity Relationship in Ethylene Oligomerization Reaction

    KAUST Repository

    Hamieh, Ali Imad Ali

    2017-06-06

    Silica supported Tetramethyl niobium complex [(≡SiO)NbMe4] 2 has been isolated by surface alkylation of [(≡SiO-)NbCl3Me] 1 with dimethyl zinc in pentane. 1 can be easily synthesized by grafting of NbCl3Me2 on to the surface of partially dehydroxylated silica by the SOMC strategy. Precise structural analysis was carried out by the FTIR, advance solid state NMR, elemental analysis and mass balance techniques (gas quantification after treating 2 with degassed water) . Complex 1 was found to be active in the ethylene oligomerization to produce up to C30, whereas to our surprise complex 2 selectively dimerizes ethylene into 1-butene in the absence of a co-catalyst at the same conversion levels.

  8. Single site silica supported tetramethyl niobium by the SOMC strategy: synthesis, characterization and structure-activity relationship in the ethylene oligomerization reaction.

    Science.gov (United States)

    Hamieh, Ali; Dey, Raju; Nekoueishahraki, Bijan; Samantaray, Manoja K; Chen, Yin; Abou-Hamad, Edy; Basset, Jean-Marie

    2017-06-27

    A silica supported tetramethyl niobium complex [([triple bond, length as m-dash]SiO)NbMe 4 ] 2 has been isolated by the surface alkylation of [([triple bond, length as m-dash]SiO-)NbCl 3 Me] 1 with dimethyl zinc in pentane. 1 can be easily synthesized by grafting NbCl 3 Me 2 onto the surface of partially dehydroxylated silica by the SOMC strategy. Precise structural analysis was carried out using FTIR, advanced solid state NMR, elemental analysis and mass balance techniques (gas quantification after treating 2 with degassed water). Complex 1 was found to be active in the ethylene oligomerization reaction, producing up to C 30 , whereas to our surprise complex 2 selectively dimerized ethylene into 1-butene in the absence of a co-catalyst at the same conversion level.

  9. Niche overlap of congeneric invaders supports a single-species hypothesis and provides insight into future invasion risk: implications for global management of the Bactrocera dorsalis complex.

    Science.gov (United States)

    Hill, Matthew P; Terblanche, John S

    2014-01-01

    The invasive fruit fly, Bactrocera invadens, has expanded its range rapidly over the past 10 years. Here we aimed to determine if the recent range expansion of Bactrocera invadens into southern Africa can be better understood through niche exploration tools, ecological niche models (ENMs), and through incorporating information about Bactrocera dorsalis s.s., a putative conspecific species from Asia. We test for niche overlap of environmental variables between Bactrocera invadens and Bactrocera dorsalis s.s. as well as two other putative conspecific species, Bactrocera philippinensis and B. papayae. We examine overlap and similarity in the geographical expression of each species' realised niche through reciprocal distribution models between Africa and Asia. We explore different geographical backgrounds, environmental variables and model complexity with multiple and single Bactrocera species hypotheses in an attempt to predict the recent range expansion of B. invadens into northern parts of South Africa. Bactrocera invadens has a high degree of niche overlap with B. dorsalis s.s. (and B. philippinensis and B. papayae). Ecological niche models built for Bactrocera dorsalis s.s. have high transferability to describe the range of B. invadens, and B. invadens is able to project to the core range of B. dorsalis s.s. The ENMs of both Bactrocera dorsalis and B. dorsalis combined with B. philipenesis and B. papayae have significantly higher predictive ability to capture the distribution points in South Africa than for B. invadens alone. Consistent with other studies proposing these Bactrocera species as conspecific, niche similarity and overlap between these species is high. Considering these other Bactrocera dorsalis complex species simultaneously better describes the range expansion and invasion potential of B. invadens in South Africa. We suggest that these species should be considered the same-at least functionally-and global quarantine and management strategies applied

  10. Single-blind randomized clinical trial to evaluate clinical and radiological outcomes after one year of immediate versus delayed implant placement supporting full-arch prostheses

    Science.gov (United States)

    Pellicer-Chover, Hilario; Peñarrocha-Oltra, David; Bagán, Leticia; Fichy-Fernandez, Antonio J.; Canullo, Luigi

    2014-01-01

    Purpose: To evaluate and compare peri-implant health, marginal bone loss and success of immediate and delayed implant placement for rehabilitation with full-arch fixed prostheses. Material and Methods: The present study was a prospective, randomized, single-blind, clinical preliminary trial. Patients were randomized into two treatment groups. In Group A implants were placed immediately post-extraction and in Group B six months after extraction. The following control time-points were established: one week, six months and twelve months after loading. Measurements were taken of peri-implant crevicular fluid volume, plaque index, gingival retraction, keratinized mucosa, probing depth, modified gingival index and presence of mucositis. Implant success rates were evaluated for the two groups. The study sample included fifteen patients (nine women and six men) with a mean average age of 63.7 years. One hundred and forty-four implants were placed: 76 placed in healed sites and 68 placed immediately. Results: At the moment of prosthetic loading, keratinized mucosa width and probing depth were higher in immediate implants than delayed implants, with statistically significant differences. However, after six and twelve months, differences between groups had disappeared. Bone loss was 0.54 ± 0.39 mm for immediate implants and 0.66 ± 0.25 mm for delayed implants (p=0.201). No implants failed in either group. Conclusions: The present study with a short follow-up and a small sample yielded no statistically significant differences in implant success and peri-implant marginal bone loss between immediate and delayed implants with fixed full-arch prostheses. Peri-implant health showed no statistically significant differences for any of the studied parameters (crevicular fluid volume, plaque index, gingival retraction, keratinized mucosa, probing depth, modified gingival index and presence of mucositis) at the twelve-month follow-up. Key words:Immediate implants, delayed implants

  11. Niche Overlap of Congeneric Invaders Supports a Single-Species Hypothesis and Provides Insight into Future Invasion Risk: Implications for Global Management of the Bactrocera dorsalis Complex

    Science.gov (United States)

    Hill, Matthew P.; Terblanche, John S.

    2014-01-01

    Background The invasive fruit fly, Bactrocera invadens, has expanded its range rapidly over the past 10 years. Here we aimed to determine if the recent range expansion of Bactrocera invadens into southern Africa can be better understood through niche exploration tools, ecological niche models (ENMs), and through incorporating information about Bactrocera dorsalis s.s., a putative conspecific species from Asia. We test for niche overlap of environmental variables between Bactrocera invadens and Bactrocera dorsalis s.s. as well as two other putative conspecific species, Bactrocera philippinensis and B. papayae. We examine overlap and similarity in the geographical expression of each species’ realised niche through reciprocal distribution models between Africa and Asia. We explore different geographical backgrounds, environmental variables and model complexity with multiple and single Bactrocera species hypotheses in an attempt to predict the recent range expansion of B. invadens into northern parts of South Africa. Principal Findings Bactrocera invadens has a high degree of niche overlap with B. dorsalis s.s. (and B. philippinensis and B. papayae). Ecological niche models built for Bactrocera dorsalis s.s. have high transferability to describe the range of B. invadens, and B. invadens is able to project to the core range of B. dorsalis s.s. The ENMs of both Bactrocera dorsalis and B. dorsalis combined with B. philipenesis and B. papayae have significantly higher predictive ability to capture the distribution points in South Africa than for B. invadens alone. Conclusions/Significance Consistent with other studies proposing these Bactrocera species as conspecific, niche similarity and overlap between these species is high. Considering these other Bactrocera dorsalis complex species simultaneously better describes the range expansion and invasion potential of B. invadens in South Africa. We suggest that these species should be considered the same–at least

  12. Niche overlap of congeneric invaders supports a single-species hypothesis and provides insight into future invasion risk: implications for global management of the Bactrocera dorsalis complex.

    Directory of Open Access Journals (Sweden)

    Matthew P Hill

    Full Text Available BACKGROUND: The invasive fruit fly, Bactrocera invadens, has expanded its range rapidly over the past 10 years. Here we aimed to determine if the recent range expansion of Bactrocera invadens into southern Africa can be better understood through niche exploration tools, ecological niche models (ENMs, and through incorporating information about Bactrocera dorsalis s.s., a putative conspecific species from Asia. We test for niche overlap of environmental variables between Bactrocera invadens and Bactrocera dorsalis s.s. as well as two other putative conspecific species, Bactrocera philippinensis and B. papayae. We examine overlap and similarity in the geographical expression of each species' realised niche through reciprocal distribution models between Africa and Asia. We explore different geographical backgrounds, environmental variables and model complexity with multiple and single Bactrocera species hypotheses in an attempt to predict the recent range expansion of B. invadens into northern parts of South Africa. PRINCIPAL FINDINGS: Bactrocera invadens has a high degree of niche overlap with B. dorsalis s.s. (and B. philippinensis and B. papayae. Ecological niche models built for Bactrocera dorsalis s.s. have high transferability to describe the range of B. invadens, and B. invadens is able to project to the core range of B. dorsalis s.s. The ENMs of both Bactrocera dorsalis and B. dorsalis combined with B. philipenesis and B. papayae have significantly higher predictive ability to capture the distribution points in South Africa than for B. invadens alone. CONCLUSIONS/SIGNIFICANCE: Consistent with other studies proposing these Bactrocera species as conspecific, niche similarity and overlap between these species is high. Considering these other Bactrocera dorsalis complex species simultaneously better describes the range expansion and invasion potential of B. invadens in South Africa. We suggest that these species should be considered the same

  13. Immediate rehabilitation of the edentulous jaws with full fixed prostheses supported by four implants: interim results of a single cohort prospective study.

    Science.gov (United States)

    Agliardi, Enrico; Panigatti, Stefano; Clericò, Matteo; Villa, Cristina; Malò, Paulo

    2010-05-01

    The purpose of this study was to prospectively evaluate the clinical and radiographic outcomes of immediately loaded full-arch fixed prostheses supported by a combination of axially and non-axially positioned implants in a large cohort of patients with completely edentulous jaws, up to 5 years of function. One hundred and seventy-three edentulous patients (80 males and 93 females) were enrolled according to specific selection criteria. Each patient received a full-arch fixed prosthesis supported by two distal tilted implants and two anterior axially placed implants. The provisional functional acrylic prosthesis was delivered the same day as surgery in all cases. All cases were finalized 4-6 months later. The patients were scheduled for follow-up at 6 and 12 months of function, and annually up to 5 years. At each follow-up plaque and bleeding score was assessed and radiographic evaluation of marginal bone level was performed. The overall follow-up range was 4-59 months. A total of 154 immediately loaded prostheses (61 in the maxilla and 93 in the mandible) were in function for at least 1 year and were considered for the analysis. Four axially placed implants failed in the maxilla and one tilted implant in the mandible, all within 6 months of loading. No further implant failure occurred to date. Implant survival at 1 year was 98.36% and 99.73% for the maxilla and the mandible, respectively. Marginal bone loss at 1 year averaged 0.9+/-0.7 mm in the maxilla (204 implants) and 1.2+/-0.9 mm in the mandible (292 implants). No difference was found in marginal bone loss between axial and tilted implants. Plaque and bleeding scores progressively improved from 6 to 12 months. Fracture of the acrylic prosthesis occurred in 14% of total cases. The present preliminary results from a relatively large sample size suggest that the present technique can be considered a viable treatment option for the immediate rehabilitation of both mandible and maxilla.

  14. DNA sequences of troglobitic nicoletiid insects support Sierra de El Abra and the Sierra de Guatemala as a single biogeographical area: Implications for Astyanax

    Directory of Open Access Journals (Sweden)

    Luis Espinasa

    2014-03-01

    Full Text Available The blind Mexican tetra fish, Astyanax mexicanus, has become the most influential model for research of cave adapted organisms. Many authors assume that the Sierra de Guatemala populations and the Sierra de El Abra populations are derived from two independent colonizations. This assumption arises in part from biogeography. The 100 m high, 100 m wide Servilleta Canyon of the Boquillas River separates both mountain ranges and is an apparent barrier for troglobite dispersion. Anelpistina quinterensis (Nicoletiidae, Zygentoma, Insecta is one of the most troglomorphic nicoletiid silverfish insects ever described. 16S rRNA sequences support that this species migrated underground to reach both mountain ranges within less than 12,000 years. Furthermore, literature shows a plethora of aquatic and terrestrial cave restricted species that inhabit both mountain ranges. Thus, the Servilleta canyon has not been an effective biological barrier that prevented underground migration of troglobites between the Sierra de Guatemala and the Sierra de El Abra. The Boquillas River has changed its course throughout time. Caves that in the past connected the two Sierras were only recently geologically truncated by the erosion of the new river course. It is likely that, with the geological changes of the area and throughout the 2-8 million years of evolutionary history of cave Astyanax, there have been opportunities to migrate across the Servilleta canyon.

  15. Immediate loading of two flapless placed mandibular implants supporting cross-arch fixed prostheses: a 3-year follow-up prospective single cohort study.

    Science.gov (United States)

    Cannizzaro, Gioacchino; Felice, Pietro; Boveri, Muriel; Lazzarini, Matteo; Ferri, Vittorio; Leone, Michele; Esposito, Marco

    2014-01-01

    To evaluate the clinical outcome of two implants placed flapless in fully edentulous mandibles and immediately restored with a metal-resin screw-retained cross-arch prostheses 3 years after loading. Eighty consecutively patients were recruited. Implants for immediate loading had to be inserted with a minimum torque of 80 Ncm. Outcome measures, evaluated by two independent assessors, were: prosthesis and implant failures, complications, marginal bone level changes, implant stability quotient (ISQ) values and patient satisfaction. Three years after loading, all prostheses were in function although one patient did not come back for the 1- and 3-year follow-ups. Two implants failed early in two patients, but were successfully replaced and their prostheses remade. Twelve complications occurred in 10 patients but were all successfully treated. After 3 years, mean marginal bone loss was 0.43 mm, mean ISQ values decreased from 75.4 to 75.3, and all but four patients were fully satisfied with the therapy. Four patients were partially satisfied because, lacking molars, they could not chew as they wished. Immediately loaded mandibular cross-arch partial dentures can be supported by only two dental implants up to 3 years. Longer follow-ups (around 10 years) are needed to know the prognosis of this treatment modality.

  16. A comparison of the effects of visual deprivation and regular body weight support treadmill training on improving over-ground walking of stroke patients: a multiple baseline single subject design.

    Science.gov (United States)

    Kim, Jeong-Soo; Kang, Sun-Young; Jeon, Hye-Seon

    2015-01-01

    The body-weight-support treadmill (BWST) is commonly used for gait rehabilitation, but other forms of BWST are in development, such as visual-deprivation BWST (VDBWST). In this study, we compare the effect of VDBWST training and conventional BWST training on spatiotemporal gait parameters for three individuals who had hemiparetic strokes. We used a single-subject experimental design, alternating multiple baselines across the individuals. We recruited three individuals with hemiparesis from stroke; two on the left side and one on the right. For the main outcome measures we assessed spatiotemporal gait parameters using GAITRite, including: gait velocity; cadence; step time of the affected side (STA); step time of the non-affected side (STN); step length of the affected side (SLA); step length of the non-affected side (SLN); step-time asymmetry (ST-asymmetry); and step-length asymmetry (SL-asymmetry). Gait velocity, cadence, SLA, and SLN increased from baseline after both interventions, but STA, ST-asymmetry, and SL-asymmetry decreased from the baseline after the interventions. The VDBWST was significantly more effective than the BWST for increasing gait velocity and cadence and for decreasing ST-asymmetry. VDBWST is more effective than BWST for improving gait performance during the rehabilitation for ground walking.

  17. Assessment of Marginal Peri-implant Bone-Level Short-Length Implants Compared with Standard Implants Supporting Single Crowns in a Controlled Clinical Trial: 12-Month Follow-up.

    Science.gov (United States)

    Mendoza-Azpur, Gerardo; Lau, Miguel; Valdivia, Erick; Rojas, Jorge; Muñoz, Henry; Nevins, Myron

    In oral rehabilitation, crown-to-root ratio is accepted as an indicator of bone loss, and this concept was transferred to implants. Recent studies have indicated that there is no significant difference between short and standard implants. The aim of this study was to compare marginal bone-level alteration through radiographic evaluation and clinical parameters between short and standard implants supporting single crowns. This prospective clinical trial study included 82 systemically healthy, nonsmoking subjects. Patients were divided into two groups: one group for short dental implants measuring 5.5 or 7 mm, and one group for standard dental implants measuring 10 or 12 mm, in accordance with the individual needs of the patient. A clinical dental history was taken for each subject, including model casts, dental radiography, and cone beam computed tomography. A periapical analysis was also performed using ImageJ computer software to establish the initial bone measurement and periapical bone loss. A statistically significant difference was found in favor of the standard-length implants after 12 months, with greater gingival recession around the implant; however, bone loss in the short implants did not exceed 0.53 mm. The treatment with 5.5- to 7-mm-length implants is as reliable as treatment with 10- or 12-mm implants. Peri-implant bone loss is minimal, and therefore use of short implants can be recommended as treatment for the restoration of partially edentulous patients without the need for splinted crowns.

  18. Single Purpose Satellite Systems

    OpenAIRE

    Watkins, Warren

    1989-01-01

    This paper examines the need for tactically responsive space systems capable of supporting battlefield and fleet commanders. Terminology used to describe this category of satellite system varies according to organization or agency. The Defense Advanced Research Projects Agency's Lightsat, the Naval Space Command's SPINSAT, and the Air Force Space Command s TACSAT, are reviewed. The United State Space Command's space support mission IS addressed and the role single-purpose satellites can play ...

  19. Well-defined silica supported aluminum hydride: another step towards the utopian single site dream?† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc02276b Click here for additional data file.

    Science.gov (United States)

    Werghi, Baraa; Bendjeriou-Sedjerari, Anissa; Sofack-Kreutzer, Julien; Jedidi, Abdesslem; Abou-Hamad, Edy

    2015-01-01

    of a strained siloxane bridge, Si–O–Si but with two different mechanisms, showing that the reality of “single site” catalyst may be an utopia: DFT calculations indicate that isobutyl transfer occurs via a simple metathesis between the Al-isobutyl and O–Si bonds, while hydride transfer occurs via a two steps mechanism, the first one is a β-H elimination to Al with elimination of isobutene, whereas the second is a metathesis step between the formed Al–H bond and a O–Si bond. Thermal treatment of 1a (at 250 °C) under high vacuum (10–5 mbar) generates Al–H through a β-H elimination of isobutyl fragment. These supported well-defined Al–H which are highly stable with time, are tetra, penta and octa coordinated as demonstrated by IR and 27Al–1H J-HMQC NMR spectroscopy. All these observations indicate that surfaces atoms around the site of grafting play a considerable role in the reactivity of a single site system. PMID:28757945

  20. The impact of severity of initial illness, determined by SOFA score, and presence of anemia on outcomes among patients requiring Extra Corporal Membrane Oxygenation (ECMO) support: A single center experience.

    Science.gov (United States)

    Elabbassi, Wael; Aila, Farah Al; Chowdhury, Mohammed Andaleeb; Najib, Ahmed; Zaid, H; Michelin, M; Nooryani, Arif Al

    ECMO provides respiratory and circulatory support in critically ill patients. In our study, we report on a single center experience with ECMO and aim to identify the prognostic markers for survival to discharge from hospital. A registry was maintained on all patients who underwent ECMO implantation from September 2012 till January 2016 at a single institution. The collected data was analyzed to identify baseline characteristics, outcomes including clinical variables predictive of poor outcome. A total of 29 patients underwent ECMO implantation. The average age of patients was 42±18years. 59% were males (N=17). 19 cases had a cardiac indication for ECMO (66%) while 10 cases had a pulmonary indication (34%). On univariate analysis; presence of Multi-organ failure, SOFA score more than 18 and hemoglobin less than 10g/dl at baseline and after ECMO removal were associated with increased 30day mortality. Pearson correlation with 30day mortality showed a positive correlation with MOF (+0.562, p=0.002) and SOFA score >18 (+0.448, p=0.015) and a negative correlation with anemia (-0.507, p=0.005). 15 out of the total 29 patients (52%) died within 30days of admission. Patients with MOF (log rank: 10.926, p=0.001), SOFA score >18 (log rank: 7.758, p=0.005) and hemoglobin <10g/dl (log rank: 5.595, p=0.018) had decreased survival on 30day follow up. Although the use of ECMO as a last line in the treatment of critical patients refractory to conventional treatment measures constitutes an important improvement in their care; with 48% overall survival; patient selection and timing of ECMO initiation remains challenging. Patients who already had signs of MOF and a high SOFA score portended a poor response. Similarly for anemic patients. Hence the importance of consideration for ECMO use earlier in course of illness rather than later. Screening and aggressive treatment of anemia in those patients may help improve the outcomes. Copyright © 2017. Published by Elsevier B.V.

  1. Evaluation of the clinical and aesthetic outcomes of Straumann(®) Standard Plus implants supported single crowns placed in non-augmented healed sites in the anterior maxilla: a 5-8 years retrospective study.

    Science.gov (United States)

    Zhao, Xu; Qiao, Shi-Chong; Shi, Jun-Yu; Uemura, Naoya; Arai, Korenori; Lai, Hong-Chang

    2016-01-01

    To evaluate the long-term aesthetic outcome of the single crowns supported by soft tissue level implants placed in healed sites in the anterior maxilla region via the pink aesthetic score (PES) and the white aesthetic score (WES). According to the inclusion criteria, patients who had received a single Straumann(®) Standard Plus implant in the anterior maxilla at the Shanghai 9th People's Hospital between 2005 and 2008 were invited for a re-examination based on a number of inclusion criteria and exclusion criteria. Clinical, radiographic and aesthetic outcomes (PES/WES) were assessed during their revisit at 5-8 years after crown placement. Forty-five patients were enrolled in the study. All 45 implants were successfully integrated and most of the implants did not show signs of peri-implant disease at the time of the assessment. The marginal bone resorption was 1.10 ± 0.92 mm. The mean total PES was 8.48 ± 2.62 at the baseline, 9.57 ± 2.37 at the 6-10 months revisit and 9.01 ± 2.45 at the 5-8 years follow-up. The scores of the mesial and distal papillae increased significantly between the baseline and 6-10 months follow-up, this improvement remained stable at the 5-8 years follow-up. The scores of soft tissue level, colour of the soft tissue, soft tissue texture and the alveolar process decreased significantly between the 6-10 months and 5-8 years revisits. The mean WES was 7.83 ± 1.60 at the baseline and 7.72 ± 1.43 at the 5-8 years revisit. There was no significant difference of the WES between the baseline and 5-8 years revisit. The possibility of spontaneous papillae regeneration after implant treatment and the long-term stability of the regenerated papillae were confirmed. However, recession of the facial soft tissue has been found. The incidence of the recession at thin biotype sites tended to be higher. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  2. Always single and single again women: a qualitative study.

    Science.gov (United States)

    Lewis, K G; Moon, S

    1997-04-01

    What is it like to be a single woman today? Are the experiences of women who have always been single different from those who find themselves single again after having been married? How can family therapists promote the development of single women both individually and relationally? The purpose of this phenomenological, multiple-case study was to investigate perceptions of being single among heterosexual single women between the ages of 30 and 65. Nine focus group interviews and a semistructured, mailed questionnaire were used to collect the data. Constant comparative analyses were used to develop the findings. The findings were organized around the most salient theme that emerged from the analyses: single women have unresolved or unrecognized ambivalences about being single. This overarching theme was supported by three subassertions: (a) single women are aware of both the advantages and the drawbacks of being single; (b) single women are ambivalent about the reasons for their singleness; (c) although content with being single, many women simultaneously experience feelings of loss and grief. Implications for the clinical practice of family therapy and future research on single women are discussed.

  3. Single Electron Tunneling

    International Nuclear Information System (INIS)

    Ruggiero, Steven T.

    2005-01-01

    Financial support for this project has led to advances in the science of single-electron phenomena. Our group reported the first observation of the so-called ''Coulomb Staircase'', which was produced by tunneling into ultra-small metal particles. This work showed well-defined tunneling voltage steps of width e/C and height e/RC, demonstrating tunneling quantized on the single-electron level. This work was published in a now well-cited Physical Review Letter. Single-electron physics is now a major sub-field of condensed-matter physics, and fundamental work in the area continues to be conducted by tunneling in ultra-small metal particles. In addition, there are now single-electron transistors that add a controlling gate to modulate the charge on ultra-small photolithographically defined capacitive elements. Single-electron transistors are now at the heart of at least one experimental quantum-computer element, and single-electron transistor pumps may soon be used to define fundamental quantities such as the farad (capacitance) and the ampere (current). Novel computer technology based on single-electron quantum dots is also being developed. In related work, our group played the leading role in the explanation of experimental results observed during the initial phases of tunneling experiments with the high-temperature superconductors. When so-called ''multiple-gap'' tunneling was reported, the phenomenon was correctly identified by our group as single-electron tunneling in small grains in the material. The main focus throughout this project has been to explore single electron phenomena both in traditional tunneling formats of the type metal/insulator/particles/insulator/metal and using scanning tunneling microscopy to probe few-particle systems. This has been done under varying conditions of temperature, applied magnetic field, and with different materials systems. These have included metals, semi-metals, and superconductors. Amongst a number of results, we have

  4. PVM Support for Clusters

    Science.gov (United States)

    Springer, P.

    2000-01-01

    The latest version of PVM (3.4.3) now contains support for a PC cluster running Linux, also known as a Beowulf system. A PVM user of a computer outside the Beowulf system can add the Beowulf as a single machine.

  5. From single-site tantalum complexes to nanoparticles of TaxNy and TaOxNy supported on silica: elucidation of synthesis chemistry by dynamic nuclear polarization surface enhanced NMR spectroscopy and X-ray absorption spectroscopy

    KAUST Repository

    Mohandas, Janet Chakkamadathil

    2017-06-08

    Air-stable catalysts consisting of tantalum nitride nanoparticles represented as a mixture of TaxNy and TaOxNy with diameters in the range of 0.5 to 3 nm supported on highly dehydroxylated silica were synthesized from TaMe5 (Me = methyl) and dimeric Ta-2(OMe)(10) with guidance by the principles of surface organometallic chemistry (SOMC). Characterization of the supported precursors and the supported nanoparticles formed from them was carried out by IR, NMR, UV-Vis, extended X-ray absorption fine structure, and X-ray photoelectron spectroscopies complemented with XRD and high-resolution TEM, with dynamic nuclear polarization surface enhanced NMR spectroscopy being especially helpful by providing enhanced intensities of the signals of H-1, C-13, Si-29, and N-15 at their natural abundances. The characterization data provide details of the synthesis chemistry, including evidence of (a) O-2 insertion into Ta-CH3 species on the support and (b) a binuclear to mononuclear transformation of species formed from Ta-2(OMe)(10) on the support. A catalytic test reaction, cyclooctene epoxidation, was used to probe the supported nanoparticles, with 30% H2O2 serving as the oxidant. The catalysts gave selectivities up to 98% for the epoxide at conversions as high as 99% with a 3.4 wt% loading of Ta present as TaxNy/TaOxNy.

  6. Supporting Families to Support Students

    Science.gov (United States)

    Kelly, John; Rossen, Eric; Cowan, Katherine C.

    2018-01-01

    Collaboration between students' families and the school is an essential component to promoting student mental and behavioral health. Many schools structure their mental health services using a Multi-Tiered System of Supports that offers three different tiers of support from universal supports to personalized help for students with serious…

  7. VIDENTE: a graphical user interface and decision support system for stochastic modelling of water table fluctuations at a single location; includes documentation of the programs KALMAX, KALTFN, SSD and EMERALD and introductions to stochastic modellin

    NARCIS (Netherlands)

    Bierkens, M.F.P.; Bron, W.A.

    2000-01-01

    The VIDENTE program contains a decision support system (DSS) to choose between different models for stochastic modelling of water-table depths, and a graphical user interface to facilitate operating and running four implemented models: KALMAX, KALTFN,SSDS and EMERALD. In self-contained parts each of

  8. Supporting Members and Friends

    Science.gov (United States)

    2005-10-01

    Thank you! Over the past year, AGU has received 12,104 gifts, both large and small, from members and friends. The Union has also received corporate contributions, National Science Foundation grants, and support from the National Oceanographic Partnership Program and National Association of Geoscience Teachers. Together their generosity has benefited AGU non revenue producing programs that are critical to our science and the future health of the Union. The following list gratefully acknowledges annual gifts of $100 or more and cumulative giving of $5,000 or more. The 1919 Society ($100,000 or more) and Benefactors ($5,000-$99,999) recognize single major gifts and cumulative contributions. Three circles acknowledge annual giving: President's Circle ($1,000 or more), Leadership Circle ($200-$999), and Supporters Circle ($100-$199). Supporting Life Members, who contribute a one-time gift of $1,200 in addition to lifetime dues, are among our most loyal Supporters.

  9. Supporting Info

    Data.gov (United States)

    U.S. Environmental Protection Agency — Supporting Info. This dataset is associated with the following publication: Washington , J., and T. Jenkins. Abiotic Hydrolysis of Fluorotelomer-Based Polymers as a...

  10. Supporting Info

    Data.gov (United States)

    U.S. Environmental Protection Agency — Supporting Information. This dataset is associated with the following publication: Washington , J., T. Jenkins, and E. Weber. Identification of Unsaturated and 2H...

  11. Supporting Information

    Data.gov (United States)

    U.S. Environmental Protection Agency — This is the supporting information for the journal article. This dataset is associated with the following publication: Rankin, K., S. Mabury, T. Jenkins, and J....

  12. Syntheses, crystal structures and magnetic properties of two mixed-valence Co(iii)Co(ii) compounds derived from Schiff base ligands: field-supported single-ion-magnet behavior with easy-plane anisotropy.

    Science.gov (United States)

    Mandal, Shuvankar; Mondal, Suraj; Rajnák, Cyril; Titiš, Ján; Boča, Roman; Mohanta, Sasankasekhar

    2017-10-14

    Two μ-phenoxo-μ 1,1 -azide dinuclear Co III Co II complexes [Co III (N 3 ) 2 L 1 (μ 1,1 -N 3 )Co II (N 3 )]·MeOH (1) and [Co III (N 3 ) 2 L 2 (μ 1,1 -N 3 )Co II (N 3 )]·MeOH (2) (HL 1 and HL 2 are two Schiff base ligands having N 2 O-N 2 O compartments) both possess one hexacoordinate Co(iii) and one pentacoordinate Co(ii) center. DC magnetic susceptibility and magnetization measurements show an appreciable amount of positive magnetic anisotropy (D/hc∼ 40 cm -1 ) that is also confirmed by ab initio CASSCF calculations. AC susceptibility measurements of 1 reveal that it exhibits a slow magnetic relaxation with two relaxation channels. The external magnetic field supports the low-frequency (LF) channel that escapes on heating more progressively than the high-frequency (HF) branch. The relaxation time is as slow as τ = 255 ms at T = 1.9 K and B DC = 0.6 T, where the LF mole fraction is 69%. The complex 2 also displays similar field-supported slow magnetic relaxation with two relaxation channels.

  13. Methodology and assumptions for evaluating heating and cooling energy requirements in new single-family residential buildings: Technical support document for the PEAR (Program for Energy Analysis of Residences) microcomputer program

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Y.J.; Ritschard, R.; Bull, J.; Byrne, S.; Turiel, I.; Wilson, D.; Hsui, C.; Foley, D.

    1987-01-01

    This report provides technical documentation for a software package called PEAR (Program for Energy Analysis of Residences) developed by LBL. PEAR offers an easy-to-use and accurate method of estimating the energy savings associated with various energy conservation measures used in site-built, single-family homes. This program was designed for use by non-technical groups such as home builders, home buyers or others in the buildings industry, and developed as an integral part of a set of voluntary guidelines entitled Affordable Housing Through Energy Conservation: A Guide to Designing and Constructing Energy Efficient Homes. These guidelines provide a method for selecting and evaluating cost-effective energy conservation measures based on the energy savings estimated by PEAR. This work is part of a Department of Energy program aimed at conducting research that will improve the energy efficiency of the nation's stock of conventionally-built and manufactured homes, and presenting the results to the public in a simplified format.

  14. Mirror Support

    Science.gov (United States)

    Baron, Richard L. (Inventor)

    2013-01-01

    Disclosed herein is a method of making a mirror support comprising a composite, the composite comprising a plurality of carbon nanotubes, wherein at least two of the plurality of carbon nanotubes are bonded to each other through a bridging moiety bound to each of the two carbon nanotubes, and a laminate comprising the composite.

  15. Supporting ATLAS

    CERN Multimedia

    maximilien brice

    2003-01-01

    Eighteen feet made of stainless steel will support the barrel ATLAS detector in the cavern at Point 1. In total, the ATLAS feet system will carry approximately 6000 tons, and will give the same inclination to the detector as the LHC accelerator.

  16. Supporting Transition

    Science.gov (United States)

    Qureshi, Asima; Petrucco, James

    2018-01-01

    Meadowbrook Primary School has explored the use of The Teacher Assessment in Primary Science (TAPS) to support transition, initially for transfer to secondary school and now for transition from Early Years Foundation Stage (EYFS) into Key Stage 1 (ages 5-7). This article will consider an example of a secondary transition project and discuss the…

  17. Long-term results of dose-intensive chemotherapy with G-CSF support (TCC-NHL-91) for advanced intermediate-grade non-Hodgkin's lymphoma: a review of 59 consecutive cases treated at a single institute.

    Science.gov (United States)

    Akutsu, Miyuki; Tsunoda, Saburo; Izumi, Tohru; Tanaka, Masaru; Katano, Susumu; Inoue, Koichi; Igarashi, Seiji; Hirabayashi, Kaoru; Furukawa, Yusuke; Ohmine, Ken; Sato, Kazuya; Kobayashi, Hiroyuki; Ozawa, Keiya; Kirito, Keita; Nagashima, Takahiro; Teramukai, Satoshi; Fukushima, Masanori; Kano, Yasuhiko

    2008-01-01

    We evaluated the long-term outcome of very dose-intensive chemotherapy (TCC-NHL-91) for advanced intermediate-grade lymphoma, in which an eight-cycle regimen with 11 drugs was given with granulocyte colony-stimulating factor (G-CSF) support (total 18 weeks). Fifty-nine patients were treated during February 1, 1991 and March 31, 2001 (median age: 48 years). Forty-three patients (73%) were in a high-intermediate risk or high-risk group (HI/H) according to the age-adjusted International Prognostic Index (aa-IPI). Forty-six patients received 7 or 8 cycles of therapy. Ten of 15 patients over age 60 stopped before 7 cycles. Forty-three patients with an initial bulky mass or a residual mass received involved-field radiation. Overall, 56 patients (95%) achieved complete remission (CR). Grade 4 hematotoxicity was observed in all patients. With a median follow-up of 128 months, the 10-year overall survival (OS) and progression-free survival (PFS) rates were 76% and 61%, respectively. Neither aa-IPI risk factors nor the index itself was associated with response, OS, or PFS. One patient died of sepsis during the therapy and one died of secondary leukemia. This retrospective study suggests that the TCC-NHL-91 regimen achieves high CR, OS, and PFS in patients with advanced intermediate-grade lymphoma up to 60 years old and may be a valuable asset in the management of this disease. Further evaluation and prospective studies of the TCC-NHL-91 are warranted.

  18. Immediate loading of 2 (all-on-2) flapless-placed mandibular implants supporting cross-arch fixed prostheses: interim data from a 1-year follow-up prospective single cohort study.

    Science.gov (United States)

    Cannizzaro, Gioacchino; Felice, Pietro; Giorgi, Angelo; Lazzarini, Matteo; Ferri, Vittorio; Leone, Michele; Esposito, Marco

    2012-01-01

    To evaluate the clinical outcome of 2 implants placed flapless in fully edentulous mandibles and immediately restored with a metal-resin screw-retained cross-arch prosthesis 1 year after loading. Eighty consecutive patients were recruited. To be immediately loaded, implants had to be inserted with a minimum torque of 80 Ncm. Outcome measures, evaluated by two independent assessors, were prosthesis and implant failures, complications, marginal bone level changes, implant stability quotient (ISQ) values and patient satisfaction. Flaps were raised in 7 patients. Twelve implants in 7 patients did not reach the planned insertion torque. Four implants in 3 patients were immediately replaced by larger diameter implants and achieved the desired torque, whereas the remaining implants were immediately loaded anyway. Two implants failed early in 2 patients, but were successfully replaced and their prostheses remade. One month after loading, 72 (90%) patients declared to be completely satisfied with the therapy, 7 (9%) partially satisfied and 1 (1%) unsatisfied. One year after loading, all prostheses were in function, though one patient did not attend the 1-year control. Eight (10%) complications occurred, all successfully treated. After 1 year, the mean marginal bone loss was 0.3 mm and mean ISQ values decreased from 75.4 to 72.4. These short-term results at 1 year after loading suggest that immediately loaded mandibular cross-arch fixed prostheses can be supported by only 2 dental implants. Longer follow-ups (around 10 years) are needed to know the prognosis of this treatment modality.

  19. R-hyper-CVAD versus R-CHOP/cytarabine with high-dose therapy and autologous haematopoietic stem cell support in fit patients with mantle cell lymphoma: 20 years of single-center experience.

    Science.gov (United States)

    Widmer, Fabienne; Balabanov, Stefan; Soldini, Davide; Samaras, Panagiotis; Gerber, Bernhard; Manz, Markus G; Goede, Jeroen S

    2018-02-01

    Standard of care for untreated mantle cell lymphoma (MCL) is still debated. At the University Hospital Zurich, advanced MCL in physically fit patients is treated either with rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone induction followed by consolidating high-dose chemotherapy and autologous stem cell support (R-CHOP/HD-ASCT), or with rituximab plus fractionated cyclophosphamide, vincristine, doxorubicin and dexamethasone alternating with high-dose methotrexate-cytarabine (R-hyper-CVAD/MTX-AraC) without consolidating HD-ASCT upon physicians' and patients' choice. We retrospectively analysed the outcome and therapy tolerance in patients with MCL treated with R-CHOP/HD-ASCT or R-hyper-CVAD/MTX-AraC at the University Hospital Zurich between January 1996 and January 2016. Forty-three patients were included; 29 patients received R-CHOP/HD-ASCT and 14 patients R-hyper-CVAD/MTX-AraC. Mean age at diagnosis was 54.4 years (range 38-68 years). Thirty-five patients (81.4%) completed the entire first-line therapy (n = 24 in the R-CHOP/HD-ASCT group, n = 11 in the R-hyper-CVAD group). Of those, all patients responded and 97% achieved a complete remission (CR). With a mean follow-up of 5.7 years 10-year progression-free survival (PFS) for all patients was 32% and overall survival (OS) was 76%, with no difference between the two therapy groups. Complication-induced hospitalisation rate, haematological toxicity and economic burden were significantly higher in the R-hyper-CVAD therapy group. In contrast, quality of life and global health state were better in the R-hyper-CVAD therapy group. Both first-line therapies showed similar outcome with a median OS longer than 10 years. Due to significantly lower haematological toxicity and lower economic burden, we recommend R-CHOP/HD-ASCT as first-line therapy in fit adult patients with advanced MCL.

  20. Genetic injury in hybrid male mice exposed to low doses of /sup 60/CO. gamma. -rays or fission neutrons. 1. Response to single doses

    Energy Technology Data Exchange (ETDEWEB)

    Grahn, D.; Carnes, B.A.; Farrington, B.H.; Lee, C.H. (Argonne National Lab., IL (USA))

    1984-11-01

    Young adult male B6CF/sub 1/ mice were exposed to single whole body doses of fission neutrons or /sup 60/Co ..gamma.. rays. Postspermatogonial dominant lethal injury, incidence of reciprocal chromosome translocations induced in spermatogonia, incidence of abnormal epididymal sperm 4-6 weeks after exposure, and testis weight loss 3-6 weeks after exposure were all measured. Significant effects were seen at 1 and 2.5 rad of neutrons consistent with extrapolation from higher doses, with the exception of dominant lethal mutations, which occurred in significant excess of expectation. Dose-response functions were linear or linear-quadratic, depending upon end point, radiation quality, and dose range. For translocation frequencies, the D/sup 2/ term was negative for neutron and positive for ..gamma..-ray irradiations. RBE values varied with dose and end point. For testis weight loss and abnormal sperm over the full dose range, the RBEs were between 5 and 6. They were between 7 and 9 at lower doses (< 10 rad) for translocations. RBEs for postimplantation and total dominant lethal rates were 5-6 above 10 rad and 10-14 below 10 rad. The RBEs for preimplant losses were between 15 and 25 above 10 rad and possibly higher below 10 rad, although the data are statistically 'noisy'.

  1. Supporting ATLAS

    CERN Multimedia

    2003-01-01

    Eighteen feet made of stainless steel will support the barrel ATLAS detector in the cavern at Point 1. In total, the ATLAS feet system will carry approximately 6000 tons, and will give the same inclination to the detector as the LHC accelerator. The installation of the feet is scheduled to finish during January 2004 with an installation precision at the 1 mm level despite their height of 5.3 metres. The manufacture was carried out in Russia (Company Izhorskiye Zavody in St. Petersburg), as part of a Russian and JINR Dubna in-kind contribution to ATLAS. Involved in the installation is a team from IHEP-Protvino (Russia), the ATLAS technical co-ordination team at CERN, and the CERN survey team. In all, about 15 people are involved. After the feet are in place, the barrel toroid magnet and the barrel calorimeters will be installed. This will keep the ATLAS team busy for the entire year 2004.

  2. Support facilities

    International Nuclear Information System (INIS)

    Williamson, F.S.; Blomquist, J.A.; Fox, C.A.

    1977-01-01

    Computer support is centered on the Remote Access Data Station (RADS), which is equipped with a 1000 lpm printer, 1000 cpm reader, and a 300 cps paper tape reader with 500-foot spools. The RADS is located in a data preparation room with four 029 key punches (two of which interpret), a storage vault for archival magnetic tapes, card files, and a 30 cps interactive terminal principally used for job inquiry and routing. An adjacent room provides work space for users, with a documentation library and a consultant's office, plus file storage for programs and their documentations. The facility has approximately 2,600 square feet of working laboratory space, and includes two fully equipped photographic darkrooms, sectioning and autoradiographic facilities, six microscope cubicles, and five transmission electron microscopes and one Cambridge scanning electron microscope equipped with an x-ray energy dispersive analytical system. Ancillary specimen preparative equipment includes vacuum evaporators, freeze-drying and freeze-etching equipment, ultramicrotomes, and assorted photographic and light microscopic equipment. The extensive physical plant of the animal facilities includes provisions for holding all species of laboratory animals under controlled conditions of temperature, humidity, and lighting. More than forty rooms are available for studies of the smaller species. These have a potential capacity of more than 75,000 mice, or smaller numbers of larger species and those requiring special housing arrangements. There are also six dog kennels to accommodate approximately 750 dogs housed in runs that consist of heated indoor compartments and outdoor exercise areas

  3. Single atom spintronics

    International Nuclear Information System (INIS)

    Sullivan, M. R.; Armstrong, J. N.; Hua, S. Z.; Chopra, H. D.

    2005-01-01

    Full text: Single atom spintronics (SASS) represents the ultimate physical limit in device miniaturization. SASS is characterized by ballistic electron transport, and is a fertile ground for exploring new phenomena. In addition to the 'stationary' (field independent) scattering centers that have a small and fixed contribution to total transmission probability of electron waves, domain walls constitute an additional and enhanced source of scattering in these magnetic quantum point contacts (QPCs), the latter being both field and spin-dependent. Through the measurement of complete hysteresis loops as a function of quantized conductance, we present definitive evidence of enhanced backscattering of electron waves by atomically sharp domain walls in QPCs formed between microfabricated thin films [1]. Since domain walls move in a magnetic field, the magnitude of spin-dependent scattering changes as the QPC is cycled along its hysteresis loop. For example, as shown in the inset in Fig. 1, from zero towards saturation in a given field direction, the resistance varies as the wall is being swept away, whereas the resistance is constant upon returning from saturation towards zero, since in this segment of the hysteresis loop no domain wall is present across the contact. The observed spin-valve like behavior is realized by control over wall width and shape anisotropy. This behavior also unmistakably sets itself apart from any mechanical artifacts; additionally, measurements made on single atom contacts provide an artifact-free environment [2]. Intuitively, it is simpler to organize the observed BMR data according to all possible transitions between different conductance plateaus, as shown by the dotted line in Fig. 1; the solid circles show experimental data for Co, which follows the predicted scheme. Requisite elements for the observation of the effect will be discussed in detail along with a review of state of research in this field. Practically, the challenge lies in making

  4. Work life and mental wellbeing of single and non-single working mothers in Scandinavia.

    Science.gov (United States)

    Bull, Torill; Mittelmark, Maurice B

    2009-08-01

    This study examined levels and predictors of mental wellbeing in Scandinavian working single and non-single mothers, with a special focus on financial stress, job characteristics and work-family conflict. The European Social Survey Round 2 (2005) provided questionnaire data from 73 single and 432 non-single working mothers in Denmark, Sweden and Norway. Respondents answered questions about the outcome variables life satisfaction, happiness, and positive affect, and predictor variables financial stress, job characteristics, work-family conflict, and social support. Hierarchical multiple regression was used to assess the relationships between predictor variables and mental wellbeing outcomes. Single working mothers scored significantly lower on life satisfaction and happiness, but not on positive affect, than did non-single mothers. Financial stress was higher in the single mother group. There were no significant differences in levels of enriching or stressful job characteristics, or in levels of social support. While financial stress and work-family conflict were important predictors in both groups, the relationship between financial stress and wellbeing was far stronger in the single mother group. Confidant support was a significant predictor only in the single mother group, and social participation only in the non-single mothers group. This study suggests that the Scandinavian welfare democracies have not yet been successful in relieving the financial pressure experienced by single working mothers. Development of efficient financial support systems should be prioritized. Ways to reduce work-family conflict in both single and non-single mothers in Scandinavia should also be given increased attention.

  5. Single Audit: Single Audit Act Effectiveness Issues

    National Research Council Canada - National Science Library

    Thompson, Sally

    2002-01-01

    As discussed in the report we are releasing today, our work to review agency actions to ensure that recipients take timely and appropriate corrective actions to fix audit findings contained in single...

  6. Single photon from a single trapped atom

    International Nuclear Information System (INIS)

    Dingjan, J.; Jones, M.P.A.; Beugnon, J.; Darquiee, B.; Bergamini, S.; Browaeys, A.; Messin, G.; Grangier, P.

    2005-01-01

    Full text: A quantum treatment of the interaction between atoms and light usually begins with the simplest model system: a two-level atom interacting with a monochromatic light wave. Here we demonstrate an elegant experimental realization of this system using an optically trapped single rubidium atom illuminated by resonant light pulses. We observe Rabi oscillations, and show that this system can be used as a highly efficient triggered source of single photons with a well-defined polarisation. In contrast to other sources based on neutral atoms and trapped ions, no optical cavity is required. We achieved a flux of single photons of about 10 4 s -1 at the detector, and observe complete antibunching. This source has potential applications for distributed atom-atom entanglement using single photons. (author)

  7. Thermally stable nanoparticles on supports

    Science.gov (United States)

    Roldan Cuenya, Beatriz; Naitabdi, Ahmed R.; Behafarid, Farzad

    2012-11-13

    An inverse micelle-based method for forming nanoparticles on supports includes dissolving a polymeric material in a solvent to provide a micelle solution. A nanoparticle source is dissolved in the micelle solution. A plurality of micelles having a nanoparticle in their core and an outer polymeric coating layer are formed in the micelle solution. The micelles are applied to a support. The polymeric coating layer is then removed from the micelles to expose the nanoparticles. A supported catalyst includes a nanocrystalline powder, thin film, or single crystal support. Metal nanoparticles having a median size from 0.5 nm to 25 nm, a size distribution having a standard deviation .ltoreq.0.1 of their median size are on or embedded in the support. The plurality of metal nanoparticles are dispersed and in a periodic arrangement. The metal nanoparticles maintain their periodic arrangement and size distribution following heat treatments of at least 1,000.degree. C.

  8. Single frequency intracavity SRO

    DEFF Research Database (Denmark)

    Abitan, Haim; Buchhave, Preben

    2000-01-01

    Summary form only given. A single resonance optical parametric oscillator (SRO) is inserted intracavity to a CW high power, single frequency, and ring Nd:YVO4 laser. We obtain a stable single frequency CW SRO with output at 1.7-1.9 μm (idler) and a resonating signal at 2.3-2.6 μm. The behavior...

  9. Initial Single-Shell Tank Retrieval System mission analysis report

    International Nuclear Information System (INIS)

    Hertzel, J.S.

    1996-03-01

    This document provides the mission analysis for the Initial Single-Shell Tank Retrieval System task, which supports the Single-Shell Tank Waste Retrieval Program in its commitment to remove waste from single-shell tanks for treatment and final closure

  10. Faith in action: serving single moms.

    Science.gov (United States)

    Briggs, Crista L; Lovan, Sherry; Cornell, Audrey

    2011-01-01

    In 2009, female-headed households represented 29.9% (4.4 million) of all U.S. families, with many living below the poverty line. A church in Bowling Green, Kentucky, began a Single Mothers' Oil Change service, incorporating health screening by nurses using Pender's Health Promotion Model. Nurses are equipped to identify health barriers and offer health promotion guidance and social support to single, low-income women.

  11. Single ventricle cardiac defect

    International Nuclear Information System (INIS)

    Eren, B.; Turkmen, N.; Fedakar, R.; Cetin, V.

    2010-01-01

    Single ventricle heart is defined as a rare cardiac abnormality with a single ventricle chamber involving diverse functional and physiological defects. Our case is of a ten month-old baby boy who died shortly after admission to the hospital due to vomiting and diarrhoea. Autopsy findings revealed cyanosis of finger nails and ears. Internal examination revealed; large heart, weighing 60 grams, single ventricle, without a septum and upper membranous part. Single ventricle is a rare pathology, hence, this paper aims to discuss this case from a medico-legal point of view. (author)

  12. Deep Support Vector Machines for Regression Problems

    NARCIS (Netherlands)

    Wiering, Marco; Schutten, Marten; Millea, Adrian; Meijster, Arnold; Schomaker, Lambertus

    2013-01-01

    In this paper we describe a novel extension of the support vector machine, called the deep support vector machine (DSVM). The original SVM has a single layer with kernel functions and is therefore a shallow model. The DSVM can use an arbitrary number of layers, in which lower-level layers contain

  13. Single-instruction multiple-data execution

    CERN Document Server

    Hughes, Christopher J

    2015-01-01

    Having hit power limitations to even more aggressive out-of-order execution in processor cores, many architects in the past decade have turned to single-instruction-multiple-data (SIMD) execution to increase single-threaded performance. SIMD execution, or having a single instruction drive execution of an identical operation on multiple data items, was already well established as a technique to efficiently exploit data parallelism. Furthermore, support for it was already included in many commodity processors. However, in the past decade, SIMD execution has seen a dramatic increase in the set of

  14. Single-Molecule Spectroscopy

    Indian Academy of Sciences (India)

    IAS Admin

    GENERAL ARTICLE. Single-Molecule Spectroscopy. Every Molecule is Different! Kankan Bhattacharyya. Keywords. Single-molecule spectroscopy. (SMS), confocal microscopy,. FCS, sm-FRET, FLIM. 1 High-resolution spectrum re- fers to a spectrum consisting of very sharp lines. The sharp lines clearly display transitions to ...

  15. Single-Molecule Spectroscopy

    Indian Academy of Sciences (India)

    IAS Admin

    RESONANCE. February 2015. GENERAL ARTICLE. Single-Molecule Spectroscopy. Every Molecule is Different! Kankan Bhattacharyya. Keywords. Single-molecule ..... Resonance Energy. Transfer (FRET) is an elegant technique to measure the distance between a donor and an acceptor molecule. FRET refers to the.

  16. Single photon and nonlocality

    Indian Academy of Sciences (India)

    critical analysis of the concept of hidden variable used by the authors of [1] shows that the reasoning is not correct. Keywords. Nonlocality; single particle; hidden variables. PACS Nos 03.67.Ba; 03.65.Ta; 32.80.Lg; 07.79.Fc. 1. Introduction. Quantum nonlocality [2] for single particle is a subject of debate since the origin.

  17. Single gaze gestures

    DEFF Research Database (Denmark)

    Møllenbach, Emilie; Lilholm, Martin; Gail, Alastair

    2010-01-01

    This paper examines gaze gestures and their applicability as a generic selection method for gaze-only controlled interfaces. The method explored here is the Single Gaze Gesture (SGG), i.e. gestures consisting of a single point-to-point eye movement. Horizontal and vertical, long and short SGGs were...

  18. Understanding Single Adulthood.

    Science.gov (United States)

    Stein, Peter J.

    The life styles and life chances of the unmarried include elements of choices. Singles may be grouped and characterized according to whether their status may be considered stable or temporary. A life cycle, or continuum model of singlehood is reviewed, including its different factors, or phases. A new model for singles is proposed--a life spiral…

  19. Single-sided NMR

    CERN Document Server

    Casanova, Federico; Blümich, Bernhard

    2011-01-01

    Single-Sided NMR describes the design of the first functioning single-sided tomograph, the related measurement methods, and a number of applications. One of the key advantages to this method is the speed at which the images are obtained.

  20. Social psychological-pedagogical support of singleparent family

    Directory of Open Access Journals (Sweden)

    Ruslana Kazhuk

    2018-01-01

    Full Text Available The article deals with the definition of the concept of "incomplete family", describes the typology of single-parent families, the necessity of special social psychological and pedagogical support for children from such families and their parents has been proved. The analysis of various concepts of ―support‖has been made. The idea of psychological and pedagogical support of modern incomplete families has been determined. Key words: incomplete family, types of single-parent families, support, social support, psychological and pedagogical support of single-parent families.

  1. Single molecules and nanotechnology

    CERN Document Server

    Vogel, Horst

    2007-01-01

    This book focuses on recent advances in the rapidly evolving field of single molecule research. These advances are of importance for the investigation of biopolymers and cellular biochemical reactions, and are essential to the development of quantitative biology. Written by leading experts in the field, the articles cover a broad range of topics, including: quantum photonics of organic dyes and inorganic nanoparticles their use in detecting properties of single molecules the monitoring of single molecule (enzymatic) reactions single protein (un)folding in nanometer-sized confined volumes the dynamics of molecular interactions in biological cells The book is written for advanced students and scientists who wish to survey the concepts, techniques and results of single molecule research and assess them for their own scientific activities.

  2. Single Nanoparticle Plasmonic Sensors

    Directory of Open Access Journals (Sweden)

    Manish Sriram

    2015-10-01

    Full Text Available The adoption of plasmonic nanomaterials in optical sensors, coupled with the advances in detection techniques, has opened the way for biosensing with single plasmonic particles. Single nanoparticle sensors offer the potential to analyse biochemical interactions at a single-molecule level, thereby allowing us to capture even more information than ensemble measurements. We introduce the concepts behind single nanoparticle sensing and how the localised surface plasmon resonances of these nanoparticles are dependent upon their materials, shape and size. Then we outline the different synthetic approaches, like citrate reduction, seed-mediated and seedless growth, that enable the synthesis of gold and silver nanospheres, nanorods, nanostars, nanoprisms and other nanostructures with tunable sizes. Further, we go into the aspects related to purification and functionalisation of nanoparticles, prior to the fabrication of sensing surfaces. Finally, the recent developments in single nanoparticle detection, spectroscopy and sensing applications are discussed.

  3. Single-photon imaging

    CERN Document Server

    Seitz, Peter

    2011-01-01

    The acquisition and interpretation of images is a central capability in almost all scientific and technological domains. In particular, the acquisition of electromagnetic radiation, in the form of visible light, UV, infrared, X-ray, etc. is of enormous practical importance. The ultimate sensitivity in electronic imaging is the detection of individual photons. With this book, the first comprehensive review of all aspects of single-photon electronic imaging has been created. Topics include theoretical basics, semiconductor fabrication, single-photon detection principles, imager design and applications of different spectral domains. Today, the solid-state fabrication capabilities for several types of image sensors has advanced to a point, where uncoooled single-photon electronic imaging will soon become a consumer product. This book is giving a specialist´s view from different domains to the forthcoming “single-photon imaging” revolution. The various aspects of single-photon imaging are treated by internati...

  4. Single-Phase PLLs

    DEFF Research Database (Denmark)

    Golestan, Saeed; Guerrero, Josep M.; Quintero, Juan Carlos Vasquez

    2017-01-01

    Single-phase phase-locked loops (PLLs) are popular for the synchronization and control of single-phase gridconnected converters. They are also widely used for monitoring and diagnostic purposes in the power and energy areas. In recent years, a large number of single-phase PLLs with different...... structures and properties have been proposed in the literature. The main aim of this paper is to provide a review of these PLLs. To this end, the single-phase PLLs are first classified into two major categories: 1) power-based PLLs (pPLLs), and 2) quadrature signal generation-based PLLs (QSG......-PLLs). The members of each category are then described and their pros and cons are discussed. This work provides a deep insight into characteristics of different single-phase PLLs and, therefore, can be considered as a reference for researchers and engineers....

  5. Group Decision Process Support

    DEFF Research Database (Denmark)

    Gøtze, John; Hijikata, Masao

    1997-01-01

    Introducing the notion of Group Decision Process Support Systems (GDPSS) to traditional decision-support theorists.......Introducing the notion of Group Decision Process Support Systems (GDPSS) to traditional decision-support theorists....

  6. Single Policy Study

    DEFF Research Database (Denmark)

    Kronsell, Annica; Manners, Ian James

    2015-01-01

    Single policy studies are the most common form of European Union (EU) research. Single policy studies are widely used to understand the role of the EU in a wide variety of sectors, together with their development over time, and often offer public policy prescriptions. This chapter discusses the r...... Policy (CSDP). The examples are illustrative of how single policy studies can be designed to use different approaches in the analysis: multiple streams approach to policy-making; a comparative hypothesis testing; and feminist institutional theory.......Single policy studies are the most common form of European Union (EU) research. Single policy studies are widely used to understand the role of the EU in a wide variety of sectors, together with their development over time, and often offer public policy prescriptions. This chapter discusses...... the relevance of single policy studies in EU research and give examples of how such research can be designed and carried out. The chapter reviews three examples of single policy studies using different methods based on EU environmental policy, the EU biofuels directive, and the EU Common Security and Defence...

  7. Single neuron computation

    CERN Document Server

    McKenna, Thomas M; Zornetzer, Steven F

    1992-01-01

    This book contains twenty-two original contributions that provide a comprehensive overview of computational approaches to understanding a single neuron structure. The focus on cellular-level processes is twofold. From a computational neuroscience perspective, a thorough understanding of the information processing performed by single neurons leads to an understanding of circuit- and systems-level activity. From the standpoint of artificial neural networks (ANNs), a single real neuron is as complex an operational unit as an entire ANN, and formalizing the complex computations performed by real n

  8. Single photon ECT

    International Nuclear Information System (INIS)

    Maeda, Toshio; Matsuda, Hiroshi; Tada, Akira; Bunko, Hisashi; Koizumi, Kiyoshi

    1982-01-01

    The detectability of lesions located deep in a body or overlapped with a physiologically increased activity improve with the help of single photon ECT. In some cases, the ECT is superior to the conventional gamma camera images and X-ray CT scans in the evaluation of the location and size of lesion. The single photon ECT of the brain compares favorably with the contrast enhansed X-ray CT scans. The most important adaptation of the single photon ECT are the detection of recurrent brain tumors after craniotomy and the evaluation of ischemic heart diseases. (author)

  9. Single gene retrieval from thermally degraded DNA

    Indian Academy of Sciences (India)

    Unknown

    So, based on known geothermal gra- dients and the depth of ancient remains, one can try to estimate the chances of retrieval of single genes. Acknowledgements. We thank Prof. Gerard Peter Latawiec (University of Read- ing, UK) for his critical reading of the manuscript. This work was supported by the NSFC key project ...

  10. Stresses of Single Parenting

    Science.gov (United States)

    ... Text Size Email Print Share Stresses of Single Parenting Page Content Article Body What are some ways ... way. Check your local library for books on parenting. Local hospitals, the YMCA, and church groups often ...

  11. A Single Atom Antenna

    International Nuclear Information System (INIS)

    Trinter, Florian; Williams, Joshua B; Weller, Miriam; Waitz, Markus; Pitzer, Martin; Voigtsberger, Jörg; Schober, Carl; Kastirke, Gregor; Müller, Christian; Goihl, Christoph; Burzynski, Phillip; Wiegandt, Florian; Wallauer, Robert; Kalinin, Anton; Schmidt, Lothar Ph H; Schöffler, Markus S; Jahnke, Till; Dörner, Reinhard; Chiang, Ying-Chih; Gokhberg, Kirill

    2015-01-01

    Here we demonstrate the smallest possible implementation of an antenna-receiver complex which consists of a single (helium) atom acting as the antenna and a second (neon) atom acting as a receiver. (paper)

  12. Single Beam Holography.

    Science.gov (United States)

    Chen, Hsuan; Ruterbusch, Paul H.

    1979-01-01

    Discusses how holography can be used as part of undergraduate physics laboratories. The authors propose a single beam technique of holography, which will reduce the recording scheme as well as relax the isolation requirements. (HM)

  13. Estimates of genetic parameters of body weight in descendants of x-irradiated rat spermatogonia

    International Nuclear Information System (INIS)

    Gianola, D.; Chapman, A.B.; Rutledge, J.J.

    1977-01-01

    Effects of nine generations of 450 R per generation of ancestral spermatogonial x irradiation of inbred rats on genetic parameters of body weight at 3, 6 and 10 weeks of age and of weight gains between these periods were studied. Covariances among relatives were estimated by mixed model and regression techniques in randomly selected lines with (R) and without (C) radiation history. Analyses of the data were based on five linear genetic models combining additive direct, additive indirect (maternal), dominance and environmental effects. Parameters in these models were estimated by generalized least-squares. A model including direct and indirect genetic effects fit more closely to the data in both R and C lines. Overdominance of induced mutations did not seem to be present. Ancestral irradiation increased maternal additive genetic variances of body weights and gains but not direct genetic variances. Theoretically, due to a negative direct-maternal genetic correlation, within full-sib family selection would be ineffective in increasing body weight at six weeks in both R and C lines. However, progress from mass selection would be expected to be faster in the R lines

  14. AZFc deletions do not affect the function of human spermatogonia in vitro

    NARCIS (Netherlands)

    Nickkholgh, B.; Korver, C. M.; van Daalen, S. K. M.; van Pelt, A. M. M.; Repping, S.

    2015-01-01

    Azoospermic factor c (AZFc) deletions are the underlying cause in 10% of azoo- or severe oligozoospermia. Through extensive molecular analysis the precise genetic content of the AZFc region and the origin of its deletion have been determined. However, little is known about the effect of AZFc

  15. Aging results in molecular changes in an enriched population of undifferentiated rat spermatogonia.

    Science.gov (United States)

    Paul, Catriona; Nagano, Makoto; Robaire, Bernard

    2013-12-01

    A strong correlation exists between increasing paternal age and a decline in reproductive function. Testis aging is associated with testicular atrophy, increased DNA damage, and de novo mutations. It is unclear whether these problems arise from the spermatogonial stem cells (SSCs), a buildup of anomalies as older germ cells progress through spermatogenesis, or both. We hypothesize that with the continual divisions of SSCs that maintain the germ cell population, an alteration of these cells occurs over time. To test this, we utilized young (4-mo-old) and aged (18- and 21-mo-old) transgenic rats that express GFP in germ cells only. We first examined the number and activity of SSCs from the different age groups by transplantation. Aged rats had numerically fewer SSCs than young rats (age, we isolated an SSC-enriched population of CD9-positive (CD9(+)) cells using fluorescence-activated cell sorting (confirmed by transplantation studies) and extracted RNA for microarray analysis. In the aged CD9(+) cells, 60 transcripts were upregulated and more than 500 downregulated compared to the young cells. An altered expression was found for transcripts involved in mitosis and in DNA damage response. These results suggest molecular alterations in the SSC-enriched population of aged CD9(+) cells, implying that reproductive aging originates in the undifferentiated cells of spermatogenesis.

  16. Single-Mode VCSELs

    Science.gov (United States)

    Larsson, Anders; Gustavsson, Johan S.

    The only active transverse mode in a truly single-mode VCSEL is the fundamental mode with a near Gaussian field distribution. A single-mode VCSEL produces a light beam of higher spectral purity, higher degree of coherence and lower divergence than a multimode VCSEL and the beam can be more precisely shaped and focused to a smaller spot. Such beam properties are required in many applications. In this chapter, after discussing applications of single-mode VCSELs, we introduce the basics of fields and modes in VCSELs and review designs implemented for single-mode emission from VCSELs in different materials and at different wavelengths. This includes VCSELs that are inherently single-mode as well as inherently multimode VCSELs where higher-order modes are suppressed by mode selective gain or loss. In each case we present the current state-of-the-art and discuss pros and cons. At the end, a specific example with experimental results is provided and, as a summary, the most promising designs based on current technologies are identified.

  17. Single-Photon Optomechanics

    Science.gov (United States)

    Nunnenkamp, A.; Børkje, K.; Girvin, S. M.

    2011-08-01

    Optomechanics experiments are rapidly approaching the regime where the radiation pressure of a single photon displaces the mechanical oscillator by more than its zero-point uncertainty. We show that in this limit the power spectrum has multiple sidebands and that the cavity response has several resonances in the resolved-sideband limit. Using master-equation simulations, we also study the crossover from the weak-coupling many-photon to the single-photon strong-coupling regime. Finally, we find non-Gaussian steady states of the mechanical oscillator when multiphoton transitions are resonant. Our study provides the tools to detect and take advantage of this novel regime of optomechanics.

  18. Single well techniques

    International Nuclear Information System (INIS)

    Drost, W.

    1983-01-01

    The single well technique method includes measurement of parameters of groundwater flow in saturated rock. For determination of filtration velocity the dilution of radioactive tracer is measured, for direction logging the collimeter is rotated in the probe linked with the compass. The limiting factor for measurement of high filtration velocities is the occurrence of turbulent flow. The single well technique is used in civil engineering projects, water works and subsurface drainage of liquid waste from disposal sites. The radioactive tracer method for logging the vertical fluid movement in bore-holes is broadly used in groundwater survey and exploitation. (author)

  19. Biocatalytic Single Enzyme Nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Grate, Jay W.; Kim, Jungbae

    2004-03-31

    As an innovative way of enzyme stabilization, we recently developed a new enzyme composite of nano-meter scale that we call "single-enzyme nanoparticles (SENs)" (9). Each enzyme molecule is surrounded with a porous composite organic/inorganic network of less than a few nanometers think. This approach represents a new type of enzyme-containing nanostructure. In experiments with perotease (chymotrypsin, CT), the activity of single enzyme nanoparticle form of the enzyme was greatly stabilized compared to the free form, without imposing a serious mass transfer limitation of substrates. In this chapter we will describe the synthesis, characterization and catalytic activity of the new SENs.

  20. Single port laparoscopic surgery

    DEFF Research Database (Denmark)

    Springborg, Henrik; Istre, Olav

    2012-01-01

    potential benefits. Theoretically, cosmetic outcomes, postoperative pain and complication rates could be improved with use of single site surgery. This study describes introduction of the method in a private hospital in Denmark, in which 40 patients have been treated for benign gynecologic conditions......LESS, or laparo-endoscopic single site surgery, is a promising new method in minimally invasive surgery. An increasing number of surgical procedures are being performed using this technique, however, its large-scale adoption awaits results of prospective randomized controlled studies confirming...

  1. LENA Conversion Foils Using Single-Layer Graphene, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Our key innovation will be the use of single-layer graphene as LENA conversion foils, with appropriate microgrids and nanogrids to support the foils. Phase I...

  2. Single-Molecule Spectroscopy

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 20; Issue 2. Single-Molecule Spectroscopy: Every Molecule is Different! Kankan Bhattacharyya. General Article Volume 20 Issue 2 February 2015 pp 151-164. Fulltext. Click here to view fulltext PDF. Permanent link:

  3. Single Item Inventory Models

    NARCIS (Netherlands)

    E.M. Bazsa-Oldenkamp; P. den Iseger

    2001-01-01

    textabstractThis paper extends a fundamental result about single-item inventory systems. This approach allows more general performance measures, demand processes and order policies, and leads to easier analysis and implementation, than prior research. We obtain closed form expressions for the

  4. Single Nucleotide Polymorphism

    DEFF Research Database (Denmark)

    Børsting, Claus; Pereira, Vania; Andersen, Jeppe Dyrberg

    2014-01-01

    Single nucleotide polymorphisms (SNPs) are the most frequent DNA sequence variations in the genome. They have been studied extensively in the last decade with various purposes in mind. In this chapter, we will discuss the advantages and disadvantages of using SNPs for human identification...

  5. Single Value Devices

    NARCIS (Netherlands)

    Mader, Angelika H.; Dertien, Edwin Christian; Reidsma, Dennis

    2011-01-01

    We live in a world of continuous information overflow, but the quality of information and communication is suffering. Single value devices contribute to the information and communication quality by fo- cussing on one explicit, relevant piece of information. The information is decoupled from a

  6. Single Value Devices

    NARCIS (Netherlands)

    Mader, Angelika H.; Dertien, Edwin Christian; Reidsma, Dennis; Camurri, Antonio; Costa, Cristina

    We live in a world of continuous information overflow, but the quality of information and communication is suffering. Single value devices contribute to information and communication quality by focussing on one explicit, relevant piece of information. The information is decoupled from a computer and

  7. Single Value Devices

    NARCIS (Netherlands)

    Mader, Angelika H.; Reidsma, Dennis; Dertien, Edwin Christian; Volpe, G; Kolkmeier, Jan; Camurri, A.; Kolkmeier, Jan; Nijholt, Antinus

    2015-01-01

    We live in a world of continuous information overflow, but the quality of information and communication is suffering. Single value devices contribute to the information and communication quality by focussing on one explicit, relevant piece of information. The information is decoupled from a computer

  8. Beware the single hit!

    CERN Multimedia

    2008-01-01

    The first time that single particle effects from cosmic rays on electronics were observed was in 1991, when one of the instruments aboard an ESA satellite broke down after only five days in space. On 5 July, the TS-LEA group will have completed the installation of monitors that will help to reduce similar dangerous effects on LHC electronics.

  9. Single reusable spacecraft

    Data.gov (United States)

    National Aeronautics and Space Administration — Design of a my single person reusable spacecraft. It can carry one person and it has to be dropped from an aircraft at an altitude of 40,000 - 45,000 feet. Can be...

  10. Single-Molecule Spectroscopy

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 20; Issue 2. Single-Molecule Spectroscopy: Every Molecule is Different! ... Author Affiliations. Kankan Bhattacharyya1. Department of Physical Chemistry, Indian Association for the Cultivation of Science Jadavpur, Kolkata 700 032 India.

  11. Single photon and nonlocality

    Indian Academy of Sciences (India)

    In a paper by Home and Agarwal [1], it is claimed that quantum nonlocality can be revealed in a simple interferometry experiment using only single particles. A critical analysis of the concept of hidden variable used by the authors of [1] shows that the reasoning is not correct.

  12. Beyond the Single Story

    Science.gov (United States)

    McKenney, Yekaterina

    2016-01-01

    Teachers of world literature have the opportunity to help students explore the more complex reality behind the stereotypes that they often see in the media. If we don't encourage students to challenge one-dimensional "single stories" that characterize an entire people--whether Muslims, Russians, Mexicans, African Americans, Chinese,…

  13. Calixarene-supported clusters

    DEFF Research Database (Denmark)

    Taylor, Stephanie M.; McIntosh, Ruaraidh D.; Piligkos, Stergios

    2012-01-01

    A combination of complementary cluster ligands results in the formation of a new calixarene-supported ferromagnetic [Mn(5)] cage that displays the characteristic bonding modes of each support.......A combination of complementary cluster ligands results in the formation of a new calixarene-supported ferromagnetic [Mn(5)] cage that displays the characteristic bonding modes of each support....

  14. Flowcharts as Technical Support

    Science.gov (United States)

    Caudill, Jason

    2007-01-01

    Any time technology is employed in an organization there is a need to provide support for the users. Such support usually needs to be offered at the location where users are trying to access the technological resources. More often than not, the user who needs the support wants to get the support immediately, not at some point in the future after a…

  15. Underground mining operation supports

    Energy Technology Data Exchange (ETDEWEB)

    Khusid, M.B.; Kozel, A.M.

    1980-12-10

    Underground mining operation supports include the supporting layer surrounded by a cylindrical jacket of cemented rock. To decrease the loss of support material due to the decreasing rock pressure on the supporting layer, the cylindrical jacket of cemented rock has an uncemented layer inside, dividing it into 2 concentric cylindrical parts.

  16. Perceptions of Parent School Collaboration within Single Parent Households

    Science.gov (United States)

    Josafat, Jason Marc

    2015-01-01

    Little is known regarding the involvement levels of single parents in their child's education or what schools can do to support the collaborative involvement with single parents. This is important, because parent involvement is crucial for student success, and schools play an important part in garnering this role towards parent involvement; single…

  17. Single sheet iron oxides

    DEFF Research Database (Denmark)

    Yin, Zhou

    activity. LDH single sheets have been reported to be effective sorbents, catalysts in electrochemical and photochemical reactions, and building thin films together with other nanomaterials for designing new functionalities. Here we focus on the delamination of FeII-FeIII LDHs into single sheet iron oxide...... was rapid compared to other iron oxides, reaching equilibrium within 60 minutes. Arsenic sorption and acid-base titration data could be successfully described with a 1pk Basic Stern Model (BSM). The point of zero charge was around 8. The intrinsic surface complexation equilibrium constants (log K...... became abundant at low pH. (3) Electrochemical reduction of chlorinated compounds using an SSI modified electrode. Here, the electrochemical reactivity of SSIs coated on indium tin oxide coated glass electrodes was investigated. Iron on the SSI modified electrode showed a typical Cyclic Voltammetry...

  18. Single frequency semiconductor lasers

    CERN Document Server

    Fang, Zujie; Chen, Gaoting; Qu, Ronghui

    2017-01-01

    This book systematically introduces the single frequency semiconductor laser, which is widely used in many vital advanced technologies, such as the laser cooling of atoms and atomic clock, high-precision measurements and spectroscopy, coherent optical communications, and advanced optical sensors. It presents both the fundamentals and characteristics of semiconductor lasers, including basic F-P structure and monolithic integrated structures; interprets laser noises and their measurements; and explains mechanisms and technologies relating to the main aspects of single frequency lasers, including external cavity lasers, frequency stabilization technologies, frequency sweeping, optical phase locked loops, and so on. It paints a clear, physical picture of related technologies and reviews new developments in the field as well. It will be a useful reference to graduate students, researchers, and engineers in the field.

  19. Thermoluminescent properties of undoped and Ce-doped lutetium orthosilicate and yttrium orthosilicate single crystals and single crystalline films scintillators

    Czech Academy of Sciences Publication Activity Database

    Twardak, A.; Bilski, B.; Zorenko, Yu.; Zorenko, T.; Gorbenko, V.; Mandowska, E.; Mandowski, A.; Sidletskiy, O.; Mareš, Jiří A.

    2014-01-01

    Roč. 61, č. 1 (2014), s. 276-281 ISSN 0018-9499 Institutional support: RVO:68378271 Keywords : LSO * single crystalline films * single crystals * thermoluminescence * YSO Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.283, year: 2014

  20. Watching single molecules dance

    Science.gov (United States)

    Mehta, Amit Dinesh

    Molecular motors convert chemical energy, from ATP hydrolysis or ion flow, into mechanical motion. A variety of increasingly precise mechanical probes have been developed to monitor and perturb these motors at the single molecule level. Several outstanding questions can be best approached at the single molecule level. These include: how far does a motor progress per energy quanta consumed? how does its reaction cycle respond to load? how many productive catalytic cycles can it undergo per diffusional encounter with its track? and what is the mechanical stiffness of a single molecule connection? A dual beam optical trap, in conjunction with in vitro ensemble motility assays, has been used to characterize two members of the myosin superfamily: muscle myosin II and chick brain myosin V. Both move the helical polymer actin, but myosin II acts in large ensembles to drive muscle contraction or cytokinesis, while myosin V acts in small numbers to transport vesicles. An optical trapping apparatus was rendered sufficiently precise to identify a myosin working stroke with 1nm or so, barring systematic errors such as those perhaps due to random protein orientations. This and other light microscopic motility assays were used to characterize myosin V: unlike myosin II this vesicle transport protein moves through many increments of travel while remaining strongly bound to a single actin filament. The step size, stall force, and travel distance of myosin V reveal a remarkably efficient motor capable of moving along a helical track for over a micrometer without significantly spiraling around it. Such properties are fully consistent with the putative role of an organelle transport motor, present in small numbers to maintain movement over long ranges relative to cellular size scales. The contrast between myosin II and myosin V resembles that between a human running on the moon and one walking on earth, where the former allows for faster motion when in larger ensembles but for less

  1. Single rotor turbine engine

    Science.gov (United States)

    Platts, David A.

    2002-01-01

    There has been invented a turbine engine with a single rotor which cools the engine, functions as a radial compressor, pushes air through the engine to the ignition point, and acts as an axial turbine for powering the compressor. The invention engine is designed to use a simple scheme of conventional passage shapes to provide both a radial and axial flow pattern through the single rotor, thereby allowing the radial intake air flow to cool the turbine blades and turbine exhaust gases in an axial flow to be used for energy transfer. In an alternative embodiment, an electric generator is incorporated in the engine to specifically adapt the invention for power generation. Magnets are embedded in the exhaust face of the single rotor proximate to a ring of stationary magnetic cores with windings to provide for the generation of electricity. In this alternative embodiment, the turbine is a radial inflow turbine rather than an axial turbine as used in the first embodiment. Radial inflow passages of conventional design are interleaved with radial compressor passages to allow the intake air to cool the turbine blades.

  2. Single Atoms in Nearly Concentric Cavity

    Science.gov (United States)

    Utama, Adrian Nugraha; Nguyen, Chi Huan; Lewty, Nick; Kurtsiefer, Christian; Quantum Optics Group Team

    2017-04-01

    Strong interaction between photons and neutral single atoms are usually observed in cavity quantum electrodynamics (CQED) systems with high finesse mirrors and small physical volume. We demonstrate another approach that employs a near concentric cavity with relatively low finesse mirrors ( 100) and large physical separation between mirrors ( 10 mm). The transmission spectrum of our CQED system with trapped single atoms is observed to exhibit two resolved normal mode peaks, in which the single atom cooperativity is estimated to be around 0.4. The cooperativity of the system can be improved further by increasing the finesse of the mirrors or moving the cavity closer to the concentric point. The successful realization of concentric CQED systems will open opportunities for scaling up with applications in quantum computing. This work is supported by the National Research Foundation and Ministry of Education, Singapore.

  3. Uniform Single Valued Neutrosophic Graphs

    Directory of Open Access Journals (Sweden)

    S. Broumi

    2017-09-01

    Full Text Available In this paper, we propose a new concept named the uniform single valued neutrosophic graph. An illustrative example and some properties are examined. Next, we develop an algorithmic approach for computing the complement of the single valued neutrosophic graph. A numerical example is demonstrated for computing the complement of single valued neutrosophic graphs and uniform single valued neutrosophic graph.

  4. Single Pass Albumin Dialysis in Hepatorenal Syndrome

    Directory of Open Access Journals (Sweden)

    Rahman Ebadur

    2008-01-01

    Full Text Available Hepatorenal syndrome (HRS is the most appalling complication of acute or chronic liver disease with 90% mortality rate. Single pass albumin dialysis (SPAD can be considered as a noble liver support technique in HRS. Here, we present a case of a young healthy patient who developed hyperacute fulminant liver failure that progressed to HRS. The patient was offered SPAD as a bridge to liver transplantation, however, it resulted in an excellent recovery.

  5. Compactly supported frames for decomposition spaces

    DEFF Research Database (Denmark)

    Nielsen, Morten; Rasmussen, Kenneth Niemann

    2012-01-01

    In this article we study a construction of compactly supported frame expansions for decomposition spaces of Triebel-Lizorkin type and for the associated modulation spaces. This is done by showing that finite linear combinations of shifts and dilates of a single function with sufficient decay in b...

  6. Reactor pressure vessel support

    International Nuclear Information System (INIS)

    Butti, J.P.

    1978-01-01

    A link and pin support system provides the primary vertical and lateral support for a nuclear reactor pressure vessel without restricting thermally induced radial and vertical expansion and contraction

  7. Paladin Software Support Lab

    Data.gov (United States)

    Federal Laboratory Consortium — The Paladin Software Support Environment (SSE) occupies 2,241 square-feet. It contains the hardware and software tools required to support the Paladin Automatic Fire...

  8. Nutrition support in hospitals

    DEFF Research Database (Denmark)

    Kondrup, Jens

    2005-01-01

    Nutrition support in hospitals is becoming an area of focus because of the evidence showing improved clinical outcome with nutrition support, its status as a human rights issue and its integration into quality assurance.......Nutrition support in hospitals is becoming an area of focus because of the evidence showing improved clinical outcome with nutrition support, its status as a human rights issue and its integration into quality assurance....

  9. Single Parenthood Impact on Street Children in Ibadan Metropolis ...

    African Journals Online (AJOL)

    ... parenthood could be totally reduced if not totally eliminated from the society. Government should provide free and compulsory education to children without family support and help the less privileged parents with financial support by empowering them. Key words: Single Parenthood, Street Children, Anti-Social Behaviour,

  10. Maximum Gene-Support Tree

    Directory of Open Access Journals (Sweden)

    Yunfeng Shan

    2008-01-01

    Full Text Available Genomes and genes diversify during evolution; however, it is unclear to what extent genes still retain the relationship among species. Model species for molecular phylogenetic studies include yeasts and viruses whose genomes were sequenced as well as plants that have the fossil-supported true phylogenetic trees available. In this study, we generated single gene trees of seven yeast species as well as single gene trees of nine baculovirus species using all the orthologous genes among the species compared. Homologous genes among seven known plants were used for validation of the finding. Four algorithms—maximum parsimony (MP, minimum evolution (ME, maximum likelihood (ML, and neighbor-joining (NJ—were used. Trees were reconstructed before and after weighting the DNA and protein sequence lengths among genes. Rarely a gene can always generate the “true tree” by all the four algorithms. However, the most frequent gene tree, termed “maximum gene-support tree” (MGS tree, or WMGS tree for the weighted one, in yeasts, baculoviruses, or plants was consistently found to be the “true tree” among the species. The results provide insights into the overall degree of divergence of orthologous genes of the genomes analyzed and suggest the following: 1 The true tree relationship among the species studied is still maintained by the largest group of orthologous genes; 2 There are usually more orthologous genes with higher similarities between genetically closer species than between genetically more distant ones; and 3 The maximum gene-support tree reflects the phylogenetic relationship among species in comparison.

  11. Single Electrode Heat Effects

    DEFF Research Database (Denmark)

    Jacobsen, Torben; Broers, G. H. J.

    1977-01-01

    The heat evolution at a single irreversibly working electrode is treated onthe basis of the Brønsted heat principle. The resulting equation is analogous to the expression for the total heat evolution in a galvanic cellwith the exception that –DeltaS is substituted by the Peltier entropy, Delta......SP, of theelectrode reaction. eta is the overvoltage at the electrode. This equation is appliedto a high temperature carbonate fuel cell. It is shown that the Peltier entropyterm by far exceeds the heat production due to the irreversible losses, and thatthe main part of heat evolved at the cathode is reabsorbed...

  12. Single Port Management: Critical Link in the Reception, Staging, Onward Movement, and Integration Process

    National Research Council Canada - National Science Library

    Bush, Ralph

    1998-01-01

    .... The doctrine on single port management is still evolving and not entirely written. With clearly defined responsibilities and accepted doctrine, our ability to support geographic commanders greatly improves...

  13. Single photons on demand

    International Nuclear Information System (INIS)

    Grangier, P.; Abram, I.

    2004-01-01

    Quantum cryptography and information processing are set to benefit from developments in novel light sources that can emit photons one by one. Quantum mechanics has gained a reputation for making counter-intuitive predictions. But we rarely get the chance to witness these effects directly because, being humans, we are simply too big. Take light, for example. The light sources that are familiar to us, such as those used in lighting and imaging or in CD and DVD players, are so huge that they emit billions and billions of photons. But what if there was a light source that emitted just one photon at a time? Over the past few years, new types of light source that are able to emit photons one by one have been emerging from laboratories around the world. Pulses of light composed of a single photon correspond to power flows in the femtowatt range - a million billion times less than that of a table lamp. The driving force behind the development of these single-photon sources is a range of novel applications that take advantage of the quantum nature of light. Quantum states of superposed and entangled photons could lead the way to guaranteed-secure communication, to information processing with unprecedented speed and efficiency, and to new schemes for quantum teleportation. (U.K.)

  14. Single-borehole techniques

    International Nuclear Information System (INIS)

    Klotz, D.; Moser, H.; Trimborn, P.

    1978-01-01

    Proceeding on the theoretical considerations and on the experience and practice derived from laboratory and field testing, a system consisting of tracer injection units, detector units, measuring probe units and packers is presented, from which the different borehole probes required can be combined. A couple of examples of recent applications shows the position of the Single-Borehole Techniques with respect to the traditional methods used for the measurement of the ground-water flow. A confrontation of the permeabilities of different aquifers consents, both on the basis of the Single-Borehole Techniques as by pumping experiments, the determination of the reliability of the Point-Dilution-Method. The Point-Dilution-Method is giving information about the vertical and horizontal distribution of the permeabilities in an aquifer. By measuring the vertical current in two karst wells, the tributary horizons of a well have been determined, which gave valuable information for the subsequent well construction. Local leakages could be detected by measuring the vertical flow rate through observation wells arranged along a grout curtain erected on both sides of the retaining barrage of the Keban dam. (orig.) [de

  15. Heralded single-photon absorption by a single atom

    Science.gov (United States)

    Piro, N.; Rohde, F.; Schuck, C.; Almendros, M.; Huwer, J.; Ghosh, J.; Haase, A.; Hennrich, M.; Dubin, F.; Eschner, J.

    2011-01-01

    Emission and absorption of single photons by single atoms is a fundamental limit of matter-light interaction, manifesting its quantum mechanical nature. As a controlled process, it is also a key tool in quantum optical information technology . Controlled single-photon emission is well advanced ; for controlled single-photon absorption by a single atom, proposals exist but only preliminary experimental steps have been taken . Here we report the absorption of single photons by a single trapped ion: employing a photon pair source, detection of the quantum-correlated partner photon heralds the presence of the resonant photon at the atom. We find clear correlations between the detection of the herald and the absorption process in the atom; we also demonstrate polarization control of this process. Our experiment evidences previously unexplored interaction between a single absorber and a quantum light source; with improved control over the coupling, it will open up new avenues in quantum technology.

  16. HANARO user support and training

    Energy Technology Data Exchange (ETDEWEB)

    Seong, Baek Seok; Lee, J. S.; Sim, C. M. [KAERI, Daejeon (Korea, Republic of)

    2007-10-15

    The purpose of this project is to support external users to promote shared-use of HANARO effectively. To this end, external manpower was recruited and trained. Also, in order to broaden HANARO user-base, practice-oriented training was given. The total number of projects selected as a part of this program was 20 this year. These composed of four broad fields: neutron beam utilization, materials and nuclear fuel irradiation test, neutron activation analysis and radioisotope production. In each field, the number of projects was 11, 1, 3 and 2 respectively. In addition, considering the time spent on support, total supporting ratio has reached to an average of 14% over three fields. It was 23% for neutron beam utilization, 11% for materials/nuclear materials irradiation test, and 8% for neutron activation analysis. In order to broaden HANARO's potential user-base and increase the utilization of the HANARO experimental facility, practice-oriented HANARO user training was given. All participants from industry, academia, and national labs trained on working instruments of various fields such as neutron beam applications, materials and nuclear fuel irradiation test, and neutron activation analysis. 'HANARO (utilization and research) information management system' has been developed in an effort to create a single database. By having it available on the net, it will serve as HANARO's important 'Information Platform' along with HANARO web site

  17. From single-site tantalum complexes to nanoparticles of Ta x N y and TaO x N y supported on silica: elucidation of synthesis chemistry by dynamic nuclear polarization surface enhanced NMR spectroscopy and X-ray absorption spectroscopy.

    Science.gov (United States)

    Mohandas, Janet C; Abou-Hamad, Edy; Callens, Emmanuel; Samantaray, Manoja K; Gajan, David; Gurinov, Andrei; Ma, Tao; Ould-Chikh, Samy; Hoffman, Adam S; Gates, Bruce C; Basset, Jean-Marie

    2017-08-01

    Air-stable catalysts consisting of tantalum nitride nanoparticles represented as a mixture of Ta x N y and TaO x N y with diameters in the range of 0.5 to 3 nm supported on highly dehydroxylated silica were synthesized from TaMe 5 (Me = methyl) and dimeric Ta 2 (OMe) 10 with guidance by the principles of surface organometallic chemistry (SOMC). Characterization of the supported precursors and the supported nanoparticles formed from them was carried out by IR, NMR, UV-Vis, extended X-ray absorption fine structure, and X-ray photoelectron spectroscopies complemented with XRD and high-resolution TEM, with dynamic nuclear polarization surface enhanced NMR spectroscopy being especially helpful by providing enhanced intensities of the signals of 1 H, 13 C, 29 Si, and 15 N at their natural abundances. The characterization data provide details of the synthesis chemistry, including evidence of (a) O 2 insertion into Ta-CH 3 species on the support and (b) a binuclear to mononuclear transformation of species formed from Ta 2 (OMe) 10 on the support. A catalytic test reaction, cyclooctene epoxidation, was used to probe the supported nanoparticles, with 30% H 2 O 2 serving as the oxidant. The catalysts gave selectivities up to 98% for the epoxide at conversions as high as 99% with a 3.4 wt% loading of Ta present as Ta x N y /TaO x N y .

  18. 75 FR 9247 - Single Family Mortgage Insurance Premium, Single Family

    Science.gov (United States)

    2010-03-01

    ... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5376-N-13] Single Family Mortgage Insurance Premium, Single Family AGENCY: Office of the Chief Information Officer, HUD. ACTION: Notice... is soliciting public comments on the subject proposal. Lenders use the Single Family Premium...

  19. Optomechanics of Single Aluminum Nanodisks.

    Science.gov (United States)

    Su, Man-Nung; Dongare, Pratiksha D; Chakraborty, Debadi; Zhang, Yue; Yi, Chongyue; Wen, Fangfang; Chang, Wei-Shun; Nordlander, Peter; Sader, John E; Halas, Naomi J; Link, Stephan

    2017-04-12

    Aluminum nanostructures support tunable surface plasmon resonances and have become an alternative to gold nanoparticles. Whereas gold is the most-studied plasmonic material, aluminum has the advantage of high earth abundance and hence low cost. In addition to understanding the size and shape tunability of the plasmon resonance, the fundamental relaxation processes in aluminum nanostructures after photoexcitation must be understood to take full advantage of applications such as photocatalysis and photodetection. In this work, we investigate the relaxation following ultrafast pulsed excitation and the launching of acoustic vibrations in individual aluminum nanodisks, using single-particle transient extinction spectroscopy. We find that the transient extinction signal can be assigned to a thermal relaxation of the photoexcited electrons and phonons. The ultrafast heating-induced launching of in-plane acoustic vibrations reveals moderate binding to the glass substrate and is affected by the native aluminum oxide layer. Finally, we compare the behavior of aluminum nanodisks to that of similarly prepared and sized gold nanodisks.

  20. Supporting calculations and assumptions for use in WESF safetyanalysis

    Energy Technology Data Exchange (ETDEWEB)

    Hey, B.E.

    1997-03-07

    This document provides a single location for calculations and assumptions used in support of Waste Encapsulation and Storage Facility (WESF) safety analyses. It also provides the technical details and bases necessary to justify the contained results.

  1. Isotropic Single Negative Metamaterials

    Directory of Open Access Journals (Sweden)

    P. Protiva

    2008-09-01

    Full Text Available This paper presents the application of simple, and therefore cheap, planar resonators for building 3D isotropic metamaterials. These resonators are: a broadside-coupled split ring resonator with a magnetic response providing negative permeability; an electric dipole terminated by a loop inductor together with a double H-shaped resonator with an electric response providing negative permittivity. Two kinds of 3D isotropic single negative metamaterials are reported. The first material consists of unit cells in the form of a cube bearing on its faces six equal planar resonators with tetrahedral symmetry. In the second material, the planar resonators boxed into spherical plastic shells and randomly distributed in a hosting material compose a real 3D volumetric metamaterial with an isotropic response. In both cases the metamaterial shows negative permittivity or permeability, according to the type of resonators that are used. The experiments prove the isotropic behavior of the cells and of the metamaterial specimens.

  2. Lanthanide single molecule magnets

    CERN Document Server

    Tang, Jinkui

    2015-01-01

    This book begins by providing basic information on single-molecule magnets (SMMs), covering the magnetism of lanthanide, the characterization and relaxation dynamics of SMMs, and advanced means of studying lanthanide SMMs. It then systematically introduces lanthanide SMMs ranging from mononuclear and dinuclear to polynuclear complexes, classifying them and highlighting those SMMs with high barrier and blocking temperatures – an approach that provides some very valuable indicators for the structural features needed to optimize the contribution of an Ising type spin to a molecular magnet. The final chapter presents some of the newest developments in the lanthanide SMM field, such as the design of multifunctional and stimuli-responsive magnetic materials as well as the anchoring and organization of the SMMs on surfaces. In addition, the crystal structure and magnetic data are clearly presented with a wealth of illustrations in each chapter, helping newcomers and experts alike to better grasp ongoing trends and...

  3. Coronary single vessel disease

    International Nuclear Information System (INIS)

    Kaltenbach, M.; Kober, G.; Satter, P.; Gruentzig, A.; Myler, R.; Sterzer, S.

    1980-01-01

    The seven-years-survival rate is about 80 percent with respect to the most favourable long-time prognosis for coronary single vessel diseases under conservative therapy. In this contribution the control angiography of 76 patients after aorto-coronary bypass operation or transluminal angioplastic is reported. Only two patients subjected to a bypass operation. The recidivity rate is 10 percent after an operation, whereby it is not possible to make a recidivity prognosis. If a recidivity shows up it is being developped during the first three months. If the control angiography three months after the operation shows a good result, then a favourable steady state result can be expected. A comparison of the result with four different centers is given. (APR) [de

  4. Single-Molecule Nanomagnets

    Science.gov (United States)

    Friedman, Jonathan R.; Sarachik, Myriam P.

    2010-04-01

    Single-molecule magnets straddle the classical and quantum mechanical worlds, displaying many fascinating phenomena. They may have important technological applications in information storage and quantum computation. We review the physical properties of two prototypical molecular nanomagnets, Mn12-acetate and Fe8: Each behaves as a rigid, spin-10 object and exhibits tunneling between up and down directions. As temperature is lowered, the spin-reversal process evolves from thermal activation to pure quantum tunneling. At low temperatures, magnetic avalanches occur in which the magnetization of an entire sample rapidly reverses. We discuss the important role that symmetry-breaking fields play in driving tunneling and in producing Berry-phase interference. Recent experimental advances indicate that quantum coherence can be maintained on timescales sufficient to allow a meaningful number of quantum computing operations to be performed. Efforts are under way to create monolayers and to address and manipulate individual molecules.

  5. Single Nucleotide Polymorphism

    DEFF Research Database (Denmark)

    Børsting, Claus; Pereira, Vania; Andersen, Jeppe Dyrberg

    2014-01-01

    and briefly describe the methods that are preferred for SNP typing in forensic genetics. In addition, we will illustrate how SNPs can be used as investigative leads in the police investigation by discussing the use of ancestry informative markers and forensic DNA phenotyping. Modern DNA sequencing......Single nucleotide polymorphisms (SNPs) are the most frequent DNA sequence variations in the genome. They have been studied extensively in the last decade with various purposes in mind. In this chapter, we will discuss the advantages and disadvantages of using SNPs for human identification...... technologies (also called next generation sequencing or NGS) have the potential to completely transform forensic genetic investigations as we know them today. Here, we will make a short introduction to NGS and explain how NGS may combine analysis of the traditional forensic genetic markers with analysis...

  6. Lanthanide single molecule magnets

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Jinkui; Zhang, Peng [Chinese Academy of Sciences, Changchun (China). Changchun Inst. of Applied Chemistry

    2015-10-01

    This book begins by providing basic information on single-molecule magnets (SMMs), covering the magnetism of lanthanide, the characterization and relaxation dynamics of SMMs and advanced means of studying lanthanide SMMs. It then systematically introduces lanthanide SMMs ranging from mononuclear and dinuclear to polynuclear complexes, classifying them and highlighting those SMMs with high barrier and blocking temperatures - an approach that provides some very valuable indicators for the structural features needed to optimize the contribution of an Ising type spin to a molecular magnet. The final chapter presents some of the newest developments in the lanthanide SMM field, such as the design of multifunctional and stimuli-responsive magnetic materials as well as the anchoring and organization of the SMMs on surfaces. In addition, the crystal structure and magnetic data are clearly presented with a wealth of illustrations in each chapter, helping newcomers and experts alike to better grasp ongoing trends and explore new directions.

  7. Development of BMV supports

    Energy Technology Data Exchange (ETDEWEB)

    Wala, T.; Machata, A. (Bansky Vyskumny Ustav, Prievidza (Czechoslovakia))

    1991-03-01

    Evaluates design and performance tests of the BMV-2.0-3.2 and BMV-1 powered supports developed by the Prievidza coal mines in Slovakia for medium seam mining (and thick seam mining by slicing) with caving. Design of experimental units of the supports developed in 1983 and in 1985 (the BMV-2.0-3.2), design changes introduced after the tests and design of the final versions of the BMV-1 supports successfully tested in 1988-1989 are analyzed. The BMV-1 support unit with a mass of 11,500 kg has a closed height of 2,330 mm, an open height of 3,400 mm. Bearing capacity of a hydraulic leg is 1,600 kN. The BMV-1 support has 2 legs. Maximum bearing capacity of a support unit is 2,414 kN, minimum is 2,287 kN, specific support resistance is 697 kN/m{sup 2}. Powered support dimensions, hydraulic systems, advancing and cooperation with other equipment types (e.g. shearer loaders and chain conveyors) are analyzed. Performance tests in the Novaky mine showed the BMV-1 to be superior to the MHW 446 and MHW 4500 powered supports manufactured by Hemscheidt in the FRG. 6 refs.

  8. Morocco - Enterprise Support

    Data.gov (United States)

    Millennium Challenge Corporation — The evaluation will measure the specific contribution of the training and support program on key business outcomes. There have been no rigorous evaluations conducted...

  9. Single Motherhood, Living Arrangements, and Time With Children in Japan.

    Science.gov (United States)

    Raymo, James M; Park, Hyunjoon; Iwasawa, Miho; Zhou, Yanfei

    2014-08-01

    The authors examined relationships between single parenthood and mothers' time with children in Japan. Using data from the 2011 National Survey of Households with Children (N = 1,926), they first demonstrate that time spent with children and the frequency of shared dinners are significantly lower for single mothers than for their married counterparts. For single mothers living alone, less time with children reflects long work hours and work-related stress. Single mothers coresiding with parents spend less time with children and eat dinner together less frequently than either married mothers or their unmarried counterparts not living with parents, net of (grand)parental support, work hours, income, and stress. The findings suggest that rising divorce rates and associated growth in single-mother families may have a detrimental impact on parents' time with children in Japan and that the relatively high prevalence of intergenerational coresidence among single mothers may do little to temper this impact.

  10. A single particle energies

    Energy Technology Data Exchange (ETDEWEB)

    Bodmer, A.R. [Illinois Univ., Chicago, IL (United States). Dept. of Physics]|[Argonne National Lab., IL (United States); Usmani, Q.N.; Sami, M. [Jamia Millia Islamia, New Delhi (India). Dept. of Physics

    1993-09-01

    We consider the binding energies of {Lambda} hypernuclei (HN), in particular the single-particle (s.p.) energy data, which have been obtained for a wide range of HN with mass numbers A {le} 89 and for orbital angular momenta {ell}{sub {Lambda}} {le} 4. We briefly review some of the relevant properties of A hypernuclei. These are nuclei {sub {Lambda}}{sup A}Z with baryon number A in which a single {Lambda} hyperon (baryon number = 1) is bound to an ordinary nucleus {sup A}Z consisting of A - 1 nucleons = Z protons + N neutrons. The {Lambda} hyperon is neutral, has spin 1/2, strangeness S = {minus}1, isospin I = O and a mass M{sub {Lambda}} = 1116 MeV/c{sup 2}. Although the {Lambda} interacts with a nucleon, its interaction is only about half as strong as that between two nucleons, and thus very roughly V{sub {Lambda}N} {approx} 0.5 V{sub NN}. As a result, the two-body {Lambda}N system is unbound, and the lightest bound HN is the three-body hypertriton {sub {Lambda}}{sup 3}H in which the {Lambda} is bound to a deuteron with the {Lambda}-d separation energy being only {approx} 0.1 MeV corresponding to an exponential tail of radius {approx} 15 fm! In strong interactions the strangeness S is of course conserved, and the {Lambda} is distinct from the nucleons. In a HN strangeness changes only in the weak decays of the {Lambda} which can decay either via ``free`` pionic decay {Lambda} {yields} N + {pi} or via induced decay {Lambda} + N {yields} N + N which is only possible in the presence of nucleons. Because of the small energy release the pionic decay is strongly suppressed in all but the lightest HN and the induced decay dominates. However, the weak decay lifetime {approx} 10{sup {minus}10}s is in fact close to the lifetime of a free {Lambda}. Since this is much longer than the strong interaction time {approx} 10{sup {minus}22}s we can ignore the weak interactions when considering the binding of HN, just as for ordinary nuclei.

  11. A single particle energies

    International Nuclear Information System (INIS)

    Bodmer, A.R.; Usmani, Q.N.; Sami, M.

    1993-01-01

    We consider the binding energies of Λ hypernuclei (HN), in particular the single-particle (s.p.) energy data, which have been obtained for a wide range of HN with mass numbers A ≤ 89 and for orbital angular momenta ell Λ ≤ 4. We briefly review some of the relevant properties of A hypernuclei. These are nuclei Λ A Z with baryon number A in which a single Λ hyperon (baryon number = 1) is bound to an ordinary nucleus A Z consisting of A - 1 nucleons = Z protons + N neutrons. The Λ hyperon is neutral, has spin 1/2, strangeness S = -1, isospin I = O and a mass M Λ = 1116 MeV/c 2 . Although the Λ interacts with a nucleon, its interaction is only about half as strong as that between two nucleons, and thus very roughly V ΛN ∼ 0.5 V NN . As a result, the two-body ΛN system is unbound, and the lightest bound HN is the three-body hypertriton Λ 3 H in which the Λ is bound to a deuteron with the Λ-d separation energy being only ∼ 0.1 MeV corresponding to an exponential tail of radius ∼ 15 fm exclamation point In strong interactions the strangeness S is of course conserved, and the Λ is distinct from the nucleons. In a HN strangeness changes only in the weak decays of the Λ which can decay either via ''free'' pionic decay Λ → N + π or via induced decay Λ + N → N + N which is only possible in the presence of nucleons. Because of the small energy release the pionic decay is strongly suppressed in all but the lightest HN and the induced decay dominates. However, the weak decay lifetime ∼ 10 -10 s is in fact close to the lifetime of a free Λ. Since this is much longer than the strong interaction time ∼ 10 -22 s we can ignore the weak interactions when considering the binding of HN, just as for ordinary nuclei

  12. Product Support Manager Guidebook

    Science.gov (United States)

    2011-04-01

    traceability preventing requirements creep. Continuously influence the deployed system design for support Identify and address supportability cost...Item Unique Identification (IUID) 4.17.3. Radio Frequency Identification ( RFID ) 4.18. Shelf Life Management 4.19. Buffer Management PSM Guidebook...Reliability Centered Maintenance RDD Required Delivery Date RDT&E Research, Development, Test, and Evaluation RFID Radio Frequency Identification

  13. Nanostructured catalyst supports

    Science.gov (United States)

    Zhu, Yimin; Goldman, Jay L.; Qian, Baixin; Stefan, Ionel C.

    2012-10-02

    The present invention relates to SiC nanostructures, including SiC nanopowder, SiC nanowires, and composites of SiC nanopowder and nanowires, which can be used as catalyst supports in membrane electrode assemblies and in fuel cells. The present invention also relates to composite catalyst supports comprising nanopowder and one or more inorganic nanowires for a membrane electrode assembly.

  14. Cable Supported Bridges

    DEFF Research Database (Denmark)

    Gimsing, Niels Jørgen

    Cable supported bridges in the form of suspension bridges and cable-stayed bridges are distinguished by their ability to overcome large spans.The book concentrates on the synthesis of cable supported bridges, covering both design and construction aspects. The analytical part covers simple methods...

  15. Decision Support Tool

    NARCIS (Netherlands)

    Ritsema van Eck, Gerard; Ceross, Aaron

    The decision support tool is part of the toolkit for policy makers which came out of the FP7 RESPECT project, which dealt with privacy and surveillance. It's aim is to support decision makers at all levels of government who face difficult decisions regarding the implementation of surveillance

  16. Magnetic support system

    NARCIS (Netherlands)

    Nijsse, G.J.P.; Spronck, J.W.

    1999-01-01

    There is described a support system enabling supporting an object such as a platform (1) free from vibration, in that bearing elements (50) have a stiffness (k) which at a working point (z0) equals zero. A bearing element (50) comprises two magnetic couplings (51, 52) provided by permanent magnets

  17. Supporting Inclusive Growth

    International Development Research Centre (IDRC) Digital Library (Canada)

    msandilands

    2010-10-27

    Oct 27, 2010 ... United Nations Development Programme. WRC. Women's Rights and Citizenship ... The goal of the Supporting Inclusive Growth (SIG) program is to support rigorous and policy-oriented research that ... Exploring synergies with IDRC's Environmental Economics program and other lead players outside the ...

  18. The single entity option

    International Nuclear Information System (INIS)

    Friedlander, M.C.; Roberts, K.M.

    1997-01-01

    Traditionally, an owner hires an engineer to design a power facility or other project and then circulates the completed plans to several contractors for competitive bidding. Although there are many variations on this theme, there is an alternative method which is growing in popularity--the design-build concept. In this construction method, the same entity designs and constructs the facility. The design builder may be a single firm with both design and construction capacity in-house, or it may be a combination of two or more firms with complementary abilities. If there are multiple firms, they may be structured as a joint venture or with one of the firms prime and the others in a subcontracting role. The critical aspect is that the owner contracts with one entity which has the responsibility for both designing and constructing the facility. According to statistics compiled by the Design-Build Institute of America and F.W. Dodge DATALINE2, a national reporter of construction statistics and information, from April 1995 to April 1996 the number of design-build contracts increased 103 percent over the previous year. Of a total $212 billion construction market, about $37.2 billion--18 percent--was design build. The strongest growth was in the category of industrial--plants, refineries, factories and warehouses--in which the concept use was up more than 300 percent from the previous year

  19. VIDENTE 1.1: a graphical user interface and decision support system for stochastic modelling of water table fluctuations at a single location; includes documentation of the programs KALMAX, KALTFN, SSD and EMERALD and introductions to stochastic modelling; 2nd rev. ed

    NARCIS (Netherlands)

    Bierkens, M.F.P.; Bron, W.A.; Knotters, M.

    2002-01-01

    A description is given of the program VIDENTE. VIDENTE contains a decision support system to choose between different models for stochastic modelling of water-table depths and a graphical user interface to facilitate operating and running four implemented models: KALMAX, KALTFN, SSD and EMERALD. In

  20. Mathematical Modeling Of Life-Support Systems

    Science.gov (United States)

    Seshan, Panchalam K.; Ganapathi, Balasubramanian; Jan, Darrell L.; Ferrall, Joseph F.; Rohatgi, Naresh K.

    1994-01-01

    Generic hierarchical model of life-support system developed to facilitate comparisons of options in design of system. Model represents combinations of interdependent subsystems supporting microbes, plants, fish, and land animals (including humans). Generic model enables rapid configuration of variety of specific life support component models for tradeoff studies culminating in single system design. Enables rapid evaluation of effects of substituting alternate technologies and even entire groups of technologies and subsystems. Used to synthesize and analyze life-support systems ranging from relatively simple, nonregenerative units like aquariums to complex closed-loop systems aboard submarines or spacecraft. Model, called Generic Modular Flow Schematic (GMFS), coded in such chemical-process-simulation languages as Aspen Plus and expressed as three-dimensional spreadsheet.

  1. Stress and social support.

    Science.gov (United States)

    Baqutayan, Shadiya

    2011-01-01

    This is an experimental study and it discusses the effectiveness of social support in managing academic stress among students. The purpose of this study is to understand the importance of social support in managing stress. Simple random sampling was assigned to a number of 120 students, equally divided into an experimental and a control group. Classes on social support as coping mechanisms were given to the experimental group only. The accumulated data were then analyzed, descriptive statistics were used to interpret and evaluate the prevalence of academic stress, and social support. Correlation analysis was employed in the examination of the relationship between stress and social support. The findings of this study indicate that there are significant differences between the experimental group and the control group in relation to stress and social support. Eventually, the experimental group proved to cope with academic stress better than the control group, and they were satisfied with their academic performance during the experimentation. Hence, it is highly advisable to encourage the students to use social support as coping mechanisms.

  2. How and Why Do Top Managers Support or Not Support Strategic IS Projects?

    NARCIS (Netherlands)

    Boonstra, A.; CruzCunha, MM; Varajao, J; Powell, P; Martinho, R

    2011-01-01

    There is much evidence that top management support is the single most important determinant of IS project success. This is especially the case in complex and large-scale IS projects. Surprisingly however, despite its crucial importance there is only limited knowledge of the types of behaviour

  3. Beyond Family-Friendly: The Construct and Measurement of Singles-Friendly Work Culture

    Science.gov (United States)

    Casper, Wendy J.; Weltman, David; Kwesiga, Eileen

    2007-01-01

    Although research has examined work-family issues and organizational support for employees' family responsibilities, few studies have explored the work-life issues of single employees without children. The current study examines single employees' perceptions of how their organizations support their work-life balance in comparison to employees with…

  4. HANARO user support

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jeong Soo; Kim, Y. J.; Seong B.S. [and others

    2003-06-01

    The purpose of this project is to support external user for the promotion of HANARO common utilization effectively. To do this, external manpower was recruited and trained. Also, in order to find out and cultivate HANARO user, practice-oriented education was done. The total number of project selected as the promotion of HANARO common utilization was 31 in this year. These composed of four fields such as neutron beam utilization, materials/nuclear materials irradiation test, neutron activation analysis and radioisotope production. In each field, the numbers of project were 17, 7, 4 and 3 respectively. At first, from a selected project of view, supporting ratio by external manpower was reached to the 58%, that is, 18 out of 31 project was supported. In each field, it was 82% for neutron beam utilization and 100% for neutron activation analysis. Also, from the utilization time point of view, supporting ratio of external manpower was reached to 30% for neutron beam utilization and 59% for neutron activation analysis. Otherwise, supporting ratio by manpower in KAERI was reached to 97%, that is, 30 out of 31 project was supported. Also, from the utilization time point of view, total supporting ratio was reached to 15%. In each field, it was 20% for neutron beam utilization, 18% for materials/nuclear materials irradiation test, 20% for neutron activation analysis and 6% for radioisotope production. In order to contribute finding and cultivating of HANARO potential user and increase utilization ratio of HANARO experimental facility, practice-oriented HANARO user education has been done. At first, 32 participants from industries, universities, institutes were educated and practiced on HRPD/SANS instrument in the field of neutron beam utilization. Otherwise, in order to support external user effectively, external manpower were trained. Also, more effective support for external user could be possible through the grasping difficulty and problem on the performance of project

  5. Single-dopant resonance in a single-electron transistor

    OpenAIRE

    Golovach, V. N.; Jehl, X.; Houzet, M.; Pierre, M.; Roche, B.; Sanquer, M.; Glazman, L. I.

    2011-01-01

    Single dopants in semiconductor nanostructures have been studied in great details recently as they are good candidates for quantum bits, provided they are coupled to a detector. Here we report coupling of a single As donor atom to a single-electron transistor (SET) in a silicon nanowire field-effect transistor. Both capacitive and tunnel coupling are achieved, the latter resulting in a dramatic increase of the conductance through the SET, by up to one order of magnitude. The experimental resu...

  6. Amitraz poisoning treatment: still supportive?

    Science.gov (United States)

    Eizadi-Mood, Nastaran; Sabzghabaee, Ali Mohammad; Gheshlaghi, Farzad; Yaraghi, Ahmad

    2011-01-01

    Amitraz is a triazapentadiene, an α2 adrenergic agonist and a member of the amidine chemical family. A limited number of human intoxication cases have been published in the literature. Lack of a clear and specific protocol for the therapy of amitraz intoxication may make its successfully managed case reports useful and valuable for other clinical practitioners in poisoning departments. The case is about a 22 years old female, single, university student, ingested a glass of amitraz poison (about 100 mL of a 20% solution) as a suicidal attempt on 11:30 am which was about 3.5 h before her hospital admission. She found nausea, vomiting, and dizziness. Immediately, her family took her to a clinic near their house. At that clinic (13:30 pm) she had miosis and they did gastric lavage , one adult dose of activated charcoal (50 g) and referred her to our Poisoning Emergency Department, where she was managed supportively and successfully. Amitraz is a poisonous chemical which may cause central nervous system depression and also respiratory/cardiovascular symptoms as well. Several studies reported that using atropine for those amitraz poisoned patients with both miosis and bradycardia resolved the problem and recommend it as the first line of drug therapy when bradycardia occurs from vagal stimulation and atrioventricular block. Management of amitraz poisoning is still considered to be supportive and symptomatic. Although the effects of activated charcoal and cathartics have not been studied, they may still be considered for treatment.

  7. HANARO user support and training

    Energy Technology Data Exchange (ETDEWEB)

    Seong, Baek Seok; Lee, J. S.; Sim, C. M. [KAERI, Daejeon (Korea, Republic of)

    2006-10-15

    The purpose of this project is to support external users to promote shared-use of HANARO effectively. To this end, external manpower was recruited and trained. Also, in order to broaden HANARO user-base, practice-oriented training was given. The total number of projects selected as a part of this program was 36 this year. These composed of four broad fields: neutron beam utilization, materials and nuclear fuel irradiation test, neutron activation analysis and radioisotope production. In each field, the number of projects was 22, 4, 6 and 4 respectively. The HANARO user supports used for these projects were carried out 40 events with 355 samples for neutron beam utilization, 16 events with 1,404 hr for materials and nuclear fuel irradiation test, 8 events with 369 samples and 4 events for radioisotope production. In order to broaden HANARO's potential user-base and increase the utilization of the HANARO experimental facility, practice-oriented HANARO user training was given. All participants from industry, academia, and national labs trained on working instruments of various fields such as neutron beam applications, materials and nuclear fuel irradiation test, and neutron activation analysis. 'HANARO (utilization and research) information management system' has been developed in an effort to create a single database. By having it available on the net, it will serve as HANARO's important 'Information Platform' along with HANARO web site

  8. Patient support systems

    International Nuclear Information System (INIS)

    Braden, A.B.; McBride, T.R.; Styblo, D.J.; Taylor, S.K.; Richey, J.B.

    1979-01-01

    A patient support system for use in computerized tomography (CT) is described. The system is particularly useful for CT scanning of the brain and also of the abdominal area. The support system consists of two moveable tables which may be translated into position for X-ray scanning of the patient's body and which may be translated incrementally and automatically to obtain scans at adjacent locations. For use with brain scans, the second table is replaced by a detachable restraint assembly which is described in detail. The support system is so designed that only a small volume of low density material will intercept the X-ray beam. (UK)

  9. The southern Benguela ecosystem supports a large and highly ...

    African Journals Online (AJOL)

    spamer

    The southern Benguela ecosystem supports a large and highly productive assemblage of epipelagic ... These results support previous single-species laboratory studies and suggest that competi- tion between the two species in the field may be .... in their visual field (Lazarro 1987). Particulate-feeding anchovy are therefore ...

  10. Editorial: Support (November 2007

    Directory of Open Access Journals (Sweden)

    Dru Lavigne

    2007-11-01

    Full Text Available What is your first thought when you encounter the term "open source support"? A programmer typing the answer to a question using a chat utility? Hours spent scouring the Internet for a working configuration sample? Contacting a support engineer at a commercial call centre? If you find it difficult to think about a support engineer, you're not alone. Actuate's recently published 2007 Open Source Survey of senior personnel from financial services, Telco, and public sector organizations across North America and Europe indicates that 46.3% of respondents cite the lack of availability of long term support as a major barrier to their company's adoption of open source technologies.

  11. Online social support networks.

    Science.gov (United States)

    Mehta, Neil; Atreja, Ashish

    2015-04-01

    Peer support groups have a long history and have been shown to improve health outcomes. With the increasing familiarity with online social networks like Facebook and ubiquitous access to the Internet, online social support networks are becoming popular. While studies have shown the benefit of these networks in providing emotional support or meeting informational needs, robust data on improving outcomes such as a decrease in health services utilization or reduction in adverse outcomes is lacking. These networks also pose unique challenges in the areas of patient privacy, funding models, quality of content, and research agendas. Addressing these concerns while creating patient-centred, patient-powered online support networks will help leverage these platforms to complement traditional healthcare delivery models in the current environment of value-based care.

  12. On rationally supported surfaces

    DEFF Research Database (Denmark)

    Gravesen, Jens; Juttler, B.; Sir, Z.

    2008-01-01

    We analyze the class of surfaces which are equipped with rational support functions. Any rational support function can be decomposed into a symmetric (even) and an antisymmetric (odd) part. We analyze certain geometric properties of surfaces with odd and even rational support functions....... In particular it is shown that odd rational support functions correspond to those rational surfaces which can be equipped with a linear field of normal vectors, which were discussed by Sampoli et al. (Sampoli, M.L., Peternell, M., Juttler, B., 2006. Rational surfaces with linear normals and their convolutions...... with rational surfaces. Comput. Aided Geom. Design 23, 179-192). As shown recently, this class of surfaces includes non-developable quadratic triangular Bezier surface patches (Lavicka, M., Bastl, B., 2007. Rational hypersurfaces with rational convolutions. Comput. Aided Geom. Design 24, 410426; Peternell, M...

  13. Hemodynamic Support in Sepsis

    Directory of Open Access Journals (Sweden)

    Fatih Yildiz

    2014-04-01

    Full Text Available Sepsis is called systemic inflammatory response syndrome due to infection. When added to organs failure and perfusion abnormality is defined in severe sepsis, Hypotension that do not respond to fluid therapy is as defined septic shock. Fluid resuscitation is a most important parts of the treatment in patients with septic shock. Ongoing hypotension that despite of the adequate fluid therapy, vasopressor support initiation is required. Sepsis and septic shock, hemodynamic support is often understood as the hemodynamic support. The different approaches to the development of methods to track and objective comes up. Patients with severe sepsis and septic shock should be follow in the intensive care unit and rapid fluid replacement and effectual hemodynamic support should be provided.

  14. IT Supporting Strategy Formulation

    NARCIS (Netherlands)

    Achterbergh, J.M.I.M.; Khosrow-Pour, M.

    2005-01-01

    This overview approaches information and communication technology (ICT) for competitive intelligence from the perspective of strategy formulation. It provides an ICT architecture for supporting the knowledge processes producing relevant knowledge for strategy formulation. To determine what this

  15. [Support in addictology: hydrotherapy].

    Science.gov (United States)

    Hibou, Alain; Bordeau, Annick; Pean, Isabelle; Rouland, Elina; Charpentier, Maud

    2013-01-01

    Hydrotherapy is a corporal mediation treatment used with patients with addictions by the Mayenne centre for addiction support therapy and prevention. A demonstration of the benefit of hydrotherapy for these patients through a patient's case.

  16. [Implant supported prostheses (1)].

    Science.gov (United States)

    del Río Highsmith, J; López Lozano, J F

    1988-11-01

    In the present article deals with a number of general considerations in the realization of prostheses over endosseous implants. The different principles to study in the construction of a fixed protesic rehabilitation implanto-supported are analyzed.

  17. Chromatography resin support

    Science.gov (United States)

    Dobos, James G.

    2002-01-01

    An apparatus and method of using an improved chromatography resin support is disclosed. The chromatography support platform is provided by a stainless steel hollow cylinder adapted for being inserted into a chromatography column. An exterior wall of the stainless steel cylinder defines a groove for carrying therein an "O"-ring. The upper surface of the stainless steel column is covered by a fine stainless steel mesh welded to the edges of the stainless steel cylinder. When placed upon a receiving ledge defined within a chromatography column, the "O"-ring provides a fluid tight seal with the inner edge wall of the chromatography cylinder. The stainless steel mesh supports the chromatography matrix and provides a back flushable support which is economical and simple to construct.

  18. Endodontic therapy or single tooth implant? A systematic review.

    Science.gov (United States)

    Torabinejad, Mahmoud; Lozada, Jaime; Puterman, Israel; White, Shane N

    2008-06-01

    Should a tooth with pulpal involvement be saved through endodontic therapy, or extracted and replaced with a single tooth implant? Within the limitations of the existing literature, this systematic review of treatment outcomes found that initial endodontic treatment had a high long-term survival rate, equivalent to replacement of a missing tooth with an implant-supported restoration. Single tooth implants should be considered as the first treatment option for patients requiring extraction and tooth replacement.

  19. Support for breastfeeding mothers.

    Science.gov (United States)

    Britton, C; McCormick, F M; Renfrew, M J; Wade, A; King, S E

    2007-01-24

    There is extensive evidence of the benefits of breastfeeding for infants and mothers. In 2003, the World Health Organization (WHO) recommended infants be fed exclusively on breast milk until six months of age. However, breastfeeding rates in many developed countries continue to be resistant to change. To assess the effectiveness of support for breastfeeding mothers. We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (January 2006), MEDLINE (1966 to November 2005), EMBASE (1974 to November 2005) and MIDIRS (1991 to September 2005). Randomised or quasi-randomised controlled trials comparing extra support for breastfeeding mothers with usual maternity care. Two authors independently assessed trial quality and extracted data. We have included 34 trials (29,385 mother-infant pairs) from 14 countries. All forms of extra support analysed together showed an increase in duration of 'any breastfeeding' (includes partial and exclusive breastfeeding) (relative risk (RR) for stopping any breastfeeding before six months 0.91, 95% confidence interval (CI) 0.86 to 0.96). All forms of extra support together had a larger effect on duration of exclusive breastfeeding than on any breastfeeding (RR 0.81, 95% CI 0.74 to 0.89). Lay and professional support together extended duration of any breastfeeding significantly (RR before 4-6 weeks 0.65, 95% 0.51 to 0.82; RR before 2 months 0.74, 95% CI 0.66 to 0.83). Exclusive breastfeeding was significantly prolonged with use of WHO/UNICEF training (RR 0.69, 95% CI 0.52 to 0.91). Maternal satisfaction was poorly reported. Additional professional support was effective in prolonging any breastfeeding, but its effects on exclusive breastfeeding were less clear. WHO/UNICEF training courses appeared to be effective for professional training. Additional lay support was effective in prolonging exclusive breastfeeding, while its effects on duration of any breastfeeding were uncertain. Effective support offered by professionals and

  20. Anode Support Creep

    DEFF Research Database (Denmark)

    2015-01-01

    Initial reduction temperature of an SOC is kept higher than the highest intended operation temperature of the SOC to keep the electrolyte under compression by the Anode Support at all temperatures equal to and below the maximum intended operation temperature.......Initial reduction temperature of an SOC is kept higher than the highest intended operation temperature of the SOC to keep the electrolyte under compression by the Anode Support at all temperatures equal to and below the maximum intended operation temperature....

  1. Decision support systems

    OpenAIRE

    Georgiana MARIN

    2008-01-01

    Decision Support Systems (DSS) are a specific class of computerized information system that supports business and organizational decision-making activities. A properly-designed DSS is an interactive software-based system intended to help decision makers compile useful information from raw data, documents, personal knowledge, and/or business models to identify and solve problems and make decisions. DSS belong to an environment with multidisciplinary foundations, including database reasearch, a...

  2. Understanding Mediation Support

    OpenAIRE

    Lanz, David; Pring, Jamie; von Burg, Corinne; Zeller, Mathias

    2017-01-01

    Recent decades have witnessed increasing institutionalization of mediation support through the establishment of mediation support structures (MSS) within foreign ministries and secretariats of multilateral organizations. This study sheds light on this trend and aims to better understand the emergence, design and development of different MSS. This study analyzes six MSS, namely those established in the United Nations (UN), the Organization for Security and Co-operation in Europe (OSCE), the Eu...

  3. Support vector machines applications

    CERN Document Server

    Guo, Guodong

    2014-01-01

    Support vector machines (SVM) have both a solid mathematical background and good performance in practical applications. This book focuses on the recent advances and applications of the SVM in different areas, such as image processing, medical practice, computer vision, pattern recognition, machine learning, applied statistics, business intelligence, and artificial intelligence. The aim of this book is to create a comprehensive source on support vector machine applications, especially some recent advances.

  4. Single Photon Double Ionization of Atomic Oxygen

    Science.gov (United States)

    Wickramarathna, Madhushani; Gorczyca, Thomas; Ballance, Connor; Stolte, Wayne

    2017-04-01

    Single photon double ionization cross sections are calculated using an R-matrix with pseudostates (RMPS) method which was recently applied by Gorczyca et al. for the double photoionization of helium. With the convergence of these theoretical calculations for the simple case of helium, we extend this methodology to consider the more complex case of oxygen double photoionization. We compare our calculated results with recent measurements at the Advanced Light Source, as well as earlier experimental measurements. Our RMPS results agree well, qualitatively, with the experimental measurements, but there exist outstanding discrepancies to be addressed. This project is supported by NASA APRA award NNX17AD41G.

  5. Advances in single chain technology.

    Science.gov (United States)

    Gonzalez-Burgos, Marina; Latorre-Sanchez, Alejandro; Pomposo, José A

    2015-10-07

    The recent ability to manipulate and visualize single atoms at atomic level has given rise to modern bottom-up nanotechnology. Similar exquisite degree of control at the individual polymeric chain level for producing functional soft nanoentities is expected to become a reality in the next few years through the full development of so-called "single chain technology". Ultra-small unimolecular soft nano-objects endowed with useful, autonomous and smart functions are the expected, long-term valuable output of single chain technology. This review covers the recent advances in single chain technology for the construction of soft nano-objects via chain compaction, with an emphasis in dynamic, letter-shaped and compositionally unsymmetrical single rings, complex multi-ring systems, single chain nanoparticles, tadpoles, dumbbells and hairpins, as well as the potential end-use applications of individual soft nano-objects endowed with useful functions in catalysis, sensing, drug delivery and other uses.

  6. LHC magnet support post

    CERN Multimedia

    1995-01-01

    A prototype magnet support for the Large Hadron Collider (LHC). The magnet supports have to bridge a difference in temperature of 300 degrees. Electrical connections, instrumentation and the posts on which the magnets stand are the only points where heat transfer can happen through conduction. They are all carefully designed to draw off heat progressively. The posts are made of 4 mm thick glass-fibre– epoxy composite material. Each post supports 10 000 kg of magnet and leaks just 0.1 W of heat. This piece required a long development period which started in the early ’90s and continued until the end of the decade. The wires next to the support post are wires from strain gauges, which are employed to measure the stress level in the material when the support is mechanically loaded. These supports are mechanically optimized to withstand a weight of up to 100Kn (10 tons) while being as thin as possible to minimize conduction heat to magnets. This is the reason why the stress measurement was extensively done...

  7. Bully Prevention in Positive Behavior Support

    OpenAIRE

    Ross, Scott W.; Horner, R. H.

    2009-01-01

    Bullying behaviors are a growing concern in U.S. schools. We present here a behavioral approach to bully prevention utilizing a schoolwide intervention. Bully prevention in positive behavior support (BP-PBS) teaches students to withhold the social rewards hypothesized to maintain bullying. A single-subject multiple baseline design across 6 students and three elementary schools was implemented in an empirical evaluation of the intervention's effectiveness. Results indicated that implementation...

  8. Nanodiamond Emitters of Single Photons

    Directory of Open Access Journals (Sweden)

    Vlasov I.I.

    2015-01-01

    Full Text Available Luminescence properties of single color centers were studied in nanodiamonds of different origin. It was found that single photon emitters could be realized even in molecularsized diamond (less than 2 nm capable of housing stable luminescent center “silicon-vacancy.” First results on incorporation of single-photon emitters based on luminescent nanodiamonds in plasmonic nanoantennas to enhance the photon count rate and directionality, diminish the fluorescence decay time, and provide polarization selectivity are presented.

  9. Control of Single-Stage Single-Phase PV inverter

    DEFF Research Database (Denmark)

    Ciobotaru, Mihai; Teodorescu, Remus; Blaabjerg, Frede

    2005-01-01

    In this paper the issue of control strategies for single-stage photovoltaic (PV) inverter is addressed. Two different current controllers have been implemented and an experimental comparison between them has been made. A complete control structure for the single-phase PV system is also presented...

  10. Do single women value early retirement more than single men?

    DEFF Research Database (Denmark)

    Danø, Anne Møller; Ejrnæs, Mette; Husted, Leif

    2005-01-01

    The focus of this paper is to analyse why a large fraction of single elderly people choose to retire early. A structural model directly based on the individual decision of labour supply is estimated on a sample of singles, where singles are defined as those who are living alone. We find that inco...... are willing to reduce the income to 81%. Men's retirement decision is mainly influenced by income and health, whereas women's retirement decision is also affected by education and unemployment experience...... and health are important determinants of the retirement decision. Furthermore, we find substantial gender differences in the retirement pattern. Healthy single women value retirement more than healthy single men and are willing to reduce their disposable income to 74% of their previous income while men...

  11. Visual Decision Support Tool for Supporting Asset ...

    Science.gov (United States)

    Abstract:Managing urban water infrastructures faces the challenge of jointly dealing with assets of diverse types, useful life, cost, ages and condition. Service quality and sustainability require sound long-term planning, well aligned with tactical and operational planning and management. In summary, the objective of an integrated approach to infrastructure asset management is to assist utilities answer the following questions:•Who are we at present?•What service do we deliver?•What do we own?•Where do we want to be in the long-term?•How do we get there?The AWARE-P approach (www.aware-p.org) offers a coherent methodological framework and a valuable portfolio of software tools. It is designed to assist water supply and wastewater utility decision-makers in their analyses and planning processes. It is based on a Plan-Do-Check-Act process and is in accordance with the key principles of the International Standards Organization (ISO) 55000 standards on asset management. It is compatible with, and complementary to WERF’s SIMPLE framework. The software assists in strategic, tactical, and operational planning, through a non-intrusive, web-based, collaborative environment where objectives and metrics drive IAM planning. It is aimed at industry professionals and managers, as well as at the consultants and technical experts that support them. It is easy to use and maximizes the value of information from multiple existing data sources, both in da

  12. Social Support of Adolescent Survivors of Child Sexual Abuse and Sexual Revictimization in Turkey.

    Science.gov (United States)

    Koçtürk, Nilüfer; Bilge, Filiz

    2018-01-01

    Sexual revictimization refers to having a history of child sexual abuse and an experience of being assaulted again in adolescence or adulthood. This descriptive study examined perceived social support of nonvictim adolescents and adolescents who had survived single sexual abuse and sexual revictimization. Participants were 210 adolescent girls, all aged between 15 and 18, selected by a convenience sampling method; 70 had survived sexual revictimization, 70 had survived single sexual abuse, and 70 were nonvictims. The Perceived Social Support Scale was administered, and a one-way ANOVA was conducted for data analysis. Perceived social support from the community was lower in the sexual revictimization group than in the single sexual abuse and comparison groups. Family social support did not differ between the sexual revictimization and single sexual abuse groups but was lower in both than in the comparison group. These results indicate that victims of sexual revictimization need social support, and both sexual revictimization and single sexual abuse victims need familial support.

  13. EPICS GPIB device support

    International Nuclear Information System (INIS)

    Winans, J.

    1993-01-01

    A GPIB device support module is used to provide access to the operating parameters of a GPIB device. GPIB devices may be accessed via National Instruments 1014 cards or via Bitbus Universal Gateways. GPIB devices typically have many parameters, each of which may be thought of in terms of the standard types of database records available in EPICS. It is the job of the device support module designer to decide how the mapping of these parameters will be made to the available record types. Once this mapping is complete, the device support module may be written. The writing of the device support module consists primarily of the construction of a parameter table. This table is used to associate the database record types with the operating parameters of the GPIB instrument. Other aspects of module design include the handling of SRQ events and errors. SRQ events are made available to the device support module if so desired. The processing of an SRQ event is completely up to the designer of the module. They may be ignored, tied to event based record processing, or anything else the designer wishes. Error conditions may be handled in a similar fashion

  14. Quantum optics with single quantum dot devices

    International Nuclear Information System (INIS)

    Zwiller, Valery; Aichele, Thomas; Benson, Oliver

    2004-01-01

    A single radiative transition in a single-quantum emitter results in the emission of a single photon. Single quantum dots are single-quantum emitters with all the requirements to generate single photons at visible and near-infrared wavelengths. It is also possible to generate more than single photons with single quantum dots. In this paper we show that single quantum dots can be used to generate non-classical states of light, from single photons to photon triplets. Advanced solid state structures can be fabricated with single quantum dots as their active region. We also show results obtained on devices based on single quantum dots

  15. Mental health among single and partnered parents in South Korea.

    Directory of Open Access Journals (Sweden)

    Kyoung Ae Kong

    Full Text Available This study compares the mental health of single parents relative to partnered parents and assesses the contribution of the social and demographic factors to this difference, examining the gender difference in it.We analyzed 12,024 single and partnered subjects, aged 30-59 years, living with children, aged 0-19 years, drawn from the 4th, 5th, and 6th Korea National Health and Nutrition Examination Survey (KNHANES dataset in South Korea conducted from 2007-2013. Mental health was evaluated by self-reported questionnaires including depressive mood for recent two weeks, presence of suicidal ideation, and the Korean version of the Alcohol Use Disorder Identification Test. Covariates included age, physical illness, socioeconomic status (family income, recipient of national basic livelihood guarantees, educational level, house ownership, job, and residential area, family structure, and support (co-residence of another adult. Multiple logistic regression was carried out and the explained fractions of each covariate was calculated.Single parents had significantly poorer mental health than their partnered counterparts, with odds ratio (OR of 2.02 (95% confidence interval (CI 1.56-2.63 for depressive symptoms, 1.69 (95% CI 1.27-2.25 for suicidal ideation, and 1.74 (95% CI 1.38-2.20 for any of the three mental health statuses (suspicious depression, suicidal ideation, and alcohol dependence after controlling for the covariates. The odds of depressive symptoms (OR = 3.13, 95% CI 2.50-3.93 and suicidal ideation (OR = 2.50, 95% CI 1.97-3.17 among both single fathers and mothers were higher than partnered parents. However, the odds of alcohol dependence were 3.6 times higher among single mothers than partnered mothers (OR = 3.58, 95% CI 1.81-7.08 and were 1.4 times greater among single fathers than partnered fathers (OR = 1.35, 95% CI 0.81-2.25. Socio-economic status explained more than 50% (except for substance use disorders of the poorer mental health in

  16. Decision support systems

    DEFF Research Database (Denmark)

    Jørgensen, L.N.; Noe, E.; Langvad, A.M.

    2007-01-01

    The highly complex knowledge of scientific disciplines makes nuanced analysis and modelling possible. However, the information produced often does not reach farmers because it is presented in a way that does not correspond to the way their work is carried out in practice. The decision support...... 1000 farmers). A sociological investigation of farmers' decision-making styles in the area of crop protection has shown that arable farmers can be divided into three major groups: (a) system-orientated farmers, (b) experience-based farmers and (c) advisory-orientated farmers. The information required...... by these three groups to make their decisions varies and therefore different ways of using decision support systems need to be provided. Decision support systems need to be developed in close dialogue and collaboration with user groups....

  17. Reactor core lower support

    International Nuclear Information System (INIS)

    1981-01-01

    This patent refers to the lower support of a nuclear reactor core, and is intended for supporting each fuel assembly of the core and for distributing the primary coolant through these assemblies. It is composed of: - A first thick plate supporting the fuel assemblies. Vertical channels are machined in this plate directly facing each assembly for the passage of the primary fluid: - A second thin plate drilled with orifices, fixed under the first plate, with no space between them, and so positioned that each orifice is directly facing one of the channels. The section of the orifices diminishes from the centre of the plate towards its periphery. The second plate can also be constituted of an assembly of juxtaposed smaller plates, each small plate being secured to the first plate independently of the neighbouring plates [fr

  18. Single-cavity SLED device

    International Nuclear Information System (INIS)

    Lippmann, B.A.

    1984-09-01

    The conventional SLED device used at SLAC requires two cavities. However, the same effect can be obtained with a single cavity; the theory and operation of the device is the same, only the hardware is changed. The single-cavity device is described here

  19. Single top t-channel

    CERN Document Server

    Faltermann, Nils

    2017-01-01

    The production of single top quarks allows to study the interplay of top quark physics and the electroweak sector of the standard model. Deviations from predictions can be a hint for physics beyond the standard model. The t-channel is the dominant production mode for single top quarks at the LHC. This talk presents the latest measurements from the ATLAS and CMS collaborations.

  20. Quantum transport through single molecules

    NARCIS (Netherlands)

    Osorio Oliveros, E.A.

    2009-01-01

    This thesis describes three-terminal transport measurements through single molecules. The interest in this field stems from the dream that single molecules will form the building blocks for future nanoscale electronic devices. The advantages are their small size -nanometers-, and their synthetic

  1. Potential support ratios

    DEFF Research Database (Denmark)

    Kjærgaard, Søren; Canudas-Romo, Vladimir

    2017-01-01

    , the prospective potential support ratio usually focuses on the current mortality schedule, or period life expectancy. Instead, in this paper we look at the actual mortality experienced by cohorts in a population, using cohort life tables. We analyse differences between the two perspectives using mortality models......, historical data, and forecasted data. Cohort life expectancy takes future mortality improvements into account, unlike period life expectancy, leading to a higher prospective potential support ratio. Our results indicate that using cohort instead of period life expectancy returns around 0.5 extra younger...

  2. Radwaste Decision Support System

    International Nuclear Information System (INIS)

    Westrom, G.; Vance, J.N.; Gelhaus, F.E.

    1989-01-01

    The purpose of the Radwaste Decision Support System (RDSS) is to provide expert advice, analysis results and instructional material relative to the treatment, handling, transport and disposal of low-level radioactive waste produced in nuclear power plants. This functional specification addresses the following topics: Functions of the RDSS, Relationships and interfaces between the function, Development of the decisions and logic tree structures embodied in waste management, Elements of the database and the characteristics required to support the decision-making process, Specific User requirements for the RDSS, Development of the user interface, Basic software architecture, and Concepts for the RDSS usage including updating and maintenance

  3. A temporary face support

    Energy Technology Data Exchange (ETDEWEB)

    Popov, V.I.; Bakhtin, V.N.; Tolkachev, N.I.

    1980-03-30

    A temporary face support is proposed. It includes a beam supported by hydraulic jacks on the housing of the cutter-loader with a working tool and rotary pressure regulator. It differs in that to decrease the volume of unsecured roofing in the face space between the leading edge of the beam and the cutting tool of the cutter-loader, the beam is hinged onto the housing of the rotary pressure regulator by a fastened connecting rod, and the hydraulic jacks are provided with additional powered elements with a mechanism that regulates the length of the cut-off plate of the hydraulic pump when the seam pressure changes.

  4. Palpability Support Demonstrated

    DEFF Research Database (Denmark)

    Brønsted, Jeppe; Grönvall, Erik; Fors, David

    2007-01-01

    the situation. The concept of palpable computing, introduced by the PalCom project, denotes systems which support such understandability. In PalCom, a set of prototype scenarios provide input for an open software architecture and a conceptual framework for palpable computing. One of these prototype scenarios...... is based on the Active Surfaces concept in which therapists rehabilitate physically and mentally impaired children by means of an activity that stimulates the children both physically and cognitively. In this paper we demonstrate how palpability can be supported in a prototype of the Active Surfaces...

  5. Single-dopant resonance in a single-electron transistor

    Science.gov (United States)

    Golovach, V. N.; Jehl, X.; Houzet, M.; Pierre, M.; Roche, B.; Sanquer, M.; Glazman, L. I.

    2011-02-01

    Single dopants in semiconductor nanostructures have been studied in great detail recently as they are good candidates for quantum bits, provided they are coupled to a detector. Here we report the coupling of a single As donor atom to a single-electron transistor (SET) in a silicon nanowire field-effect transistor. Both capacitive and tunnel coupling are achieved, the latter resulting in a dramatic increase of the conductance through the SET, by up to one order of magnitude. The experimental results are well explained by the rate-equation theory developed in parallel with the experiment.

  6. Epartners supporting behavior change

    NARCIS (Netherlands)

    Otten, W.; Blanson Henkemans, O.A.; Keulen, H. van; Janssen, J.B.; Nunen, A. van

    2013-01-01

    The present report focuses on developing a comprehensive framework that guides the design of ePartners that support behavior change to promote health. An ePartner is an interactive, virtual or embodied computer assistant to which one can communicate and that assists persons through tailored advice,

  7. Supporting Music Teacher Mentors

    Science.gov (United States)

    Zaffini, Erin Dineen

    2015-01-01

    While much discussion and research is focused on the importance of music teacher mentors for preservice teachers and novice in-service music educators, little discussion has been devoted to the topic of how we, as members of the music education profession, can support the role of music teacher mentors. This article explores some of the benefits…

  8. Supporting clinicians in infrastructuring

    DEFF Research Database (Denmark)

    Simonsen, Jesper; Hertzum, Morten; Karasti, Helena

    2015-01-01

    the notion of infrastructuring, we carry out an infrastructural analysis of eWBs and approach our joint efforts as unfolding and continuing the con-figuration of participatory design activities. We identify a need for local support and novel competences among the clinicians in order for them to engage...

  9. Participatory IT-support

    DEFF Research Database (Denmark)

    Kanstrup, Anne Marie; Bertelsen, Pernille

    2006-01-01

    Beyond the initial phases of systems design Participatory Design has potentiality to include operation and maintenance of IT systems in organizations. The paper presents this argument through reports from case studies of local IT-support coined ‘participatory IT-support’. The paper presents...

  10. Student support infrastructure

    DEFF Research Database (Denmark)

    Nøhr, Christian

    2004-01-01

    The development and diffusion of distance learning programmes has made it possible for students to choose their preferred location to study and consequently, they are expected to be able to use new technologies in order to gain necessary support in a wide range of ares. When universities implement...

  11. Supporting Information.pdf

    Indian Academy of Sciences (India)

    Administrator

    Supporting information. Excited State Dynamics of 9,9´-Bianthryl in Room Temperature Ionic Liquids as. Revealed by Picosecond Time-Resolved Fluorescence Study. Dinesh Chandra Khara, Aniruddha Paul, K. Santhosh and Anunay Samanta*. School of Chemistry, University of Hyderabad, Hyderabad 500046, India.

  12. Visual management support system

    Science.gov (United States)

    Lee Anderson; Jerry Mosier; Geoffrey Chandler

    1979-01-01

    The Visual Management Support System (VMSS) is an extension of an existing computer program called VIEWIT, which has been extensively used by the U. S. Forest Service. The capabilities of this program lie in the rapid manipulation of large amounts of data, specifically opera-ting as a tool to overlay or merge one set of data with another. VMSS was conceived to...

  13. Essential Civil Support Tasks

    Science.gov (United States)

    2010-12-01

    community over a variety of issues, such as hunger , poor employment opportunities, inadequate community services, poor housing, and labor issues...Phoenix, Arizona; Las Vegas, Nevada ; and Denver, Colorado. It established an evacuation infrastructure with unit personnel and contractor support. The

  14. [Social support after traumatism].

    Science.gov (United States)

    Maercker, A; Heim, E; Hecker, T; Thoma, M V

    2017-01-01

    The classical concept of social support has recently become of relevance again, particularly in the context of traumatized patient groups, which include refugees and migrants. This article summarizes the evidence from social support research, e. g. different types of positive effects as well as context, gender and cultural aspects. These aspects are highlighted by means of studies stemming from applied healthcare research and thus describe a wide range of health effects, e.g. increased well-being and reduced depressive symptoms, improved functional abilities, better immune status and longevity. Two new trauma-specific differentiations of the social support concept are introduced: societal acknowledgement as a trauma survivor and disclosure of traumatic experiences. Against this background several implications for working with refugees arise: promotion of self-efficacy and posttraumatic maturation as well as the treatment of mental disorders show considerable benefits from focusing on social support. Finally, possibilities emerging from digital communication media are discussed, which are particularly relevant in this context.

  15. Adhered Supported Carbon Nanotubes

    International Nuclear Information System (INIS)

    Johnson, Dale F.; Craft, Benjamin J.; Jaffe, Stephen M.

    2001-01-01

    Carbon nanotubes (NTs) in excess of 200 μm long are grown by catalytic pyrolysis of hydrocarbon vapors. The nanotubes grow continuously without the typical extinction due to catalyst encapsulation. A woven metal mesh supports the nanotubes creating a metal supported nanotube (MSNT) structure. The 140 μm wide mesh openings are completely filled by 70 nm diameter multiwalled nanotubes (MWNTs). The MWNTs are straight, uniform and highly crystalline. Their wall thickness is about 10 nm (30 graphite layers). The adherent NTs are not removed from the support in a Scotch tape pull test. A 12.5 cm 2 capacitor made from two MSNT structures immersed in 1 M KCl has a capacitance of 0.35 F and an equivalent series resistance of 0.18 Ω. Water flows through the MSNT at a flow velocity of 1 cm/min with a pressure drop of 15 inches of water. With the support removed, the MWNTs naturally form a carbon nanocomposite (CNC) paper with a specific area of 80 m 2 /gm, a bulk density of 0.21 g/cm 3 , an open pore fraction of 0.81, and a resistivity of 0.16 Ω-cm

  16. Supporting shop floor intelligence

    DEFF Research Database (Denmark)

    Carstensen, Peter; Schmidt, Kjeld; Wiil, Uffe Kock

    1999-01-01

    Many manufacturing enterprises are now trying to introduce various forms of flexible work organizations on the shop floor. However, existing computer-based production planning and control systems pose severe obstacles for autonomous working groups and other kinds of shop floor control to become......-to-day production planning by supporting intelligent and responsible workers in their situated coordination activities on the shop floor....

  17. BUSINESS ENGLISH COURSES ONLINE SUPPORT

    Directory of Open Access Journals (Sweden)

    KUČÍRKOVÁ, Lenka

    2011-12-01

    Full Text Available The paper deals with the project called Online Study Support for the Subject of Business English within the Fund of Higher Education Development of the Czech Republic. It will be created in the form of a twelve-module course in the Moodle Learning Management System (LMS on the B1 level of the Common European Framework of References for Languages. Moodle is an open source Virtual Learning Environment which is free, developed by a worldwide community and is used for study purposes. It allows the teachers to create online courses and the students to enrol in them. The course is focused on the development of business and economic terminology, on reading comprehension, listening comprehension and the work with up-to-date authentic audio-visual materials. The course comprises the topics such as business and its basic terms, business letters, business organizations, macroeconomics and microeconomics, personnel management, marketing, email, accounting and finance etc. Single units have the following structure: lead in, key words and definitions, specialist material, various activities such as filling in the gaps, multiple choice, matching, word formation, word order etc. These electronic activities are created in the most famous authoring tool in our field called Hot Potatoes, they can be stored on a central server and accessed from anywhere through the Internet. Online support will be intended for students of all faculties and fields of study at the Czech University of Life Sciences (CULS in Prague, including incoming Erasmus students and academic staff as well as the students of other universities.

  18. Single banking supervision and the single supervisory mechanism

    Directory of Open Access Journals (Sweden)

    Gheorghe, C. A.

    2013-06-01

    Full Text Available A resolution seems to have been found for the banking crisis. The first steps have been made towards the construction of the Economic and Monetary Union, steps involving the single supervision of banks, in order to avoid the discount of a new financial crisis on the expense of the EU state members. The Single Supervisory Mechanism – SSM is to become effective as of March 1, 2014, at the earliest.

  19. Settling for less out of fear of being single.

    Science.gov (United States)

    Spielmann, Stephanie S; MacDonald, Geoff; Maxwell, Jessica A; Joel, Samantha; Peragine, Diana; Muise, Amy; Impett, Emily A

    2013-12-01

    The present research demonstrates that fear of being single predicts settling for less in romantic relationships, even accounting for constructs typically examined in relationship research such as anxious attachment. Study 1 explored the content of people's thoughts about being single. Studies 2A and 2B involved the development and validation of the Fear of Being Single Scale. Study 2C provided preliminary support for the hypothesis that fear of being single predicts settling for less in ongoing relationships, as evidenced by greater dependence in unsatisfying relationships. Study 3 replicated this effect in a longitudinal study demonstrating that fear of being single predicts lower likelihood of initiating the dissolution of a less satisfying relationship. Studies 4A and 4B explored the predictive ability of fear of being single for self-reported dating standards. Across both samples, fear of being single was unrelated to self-reported standards for a mate, with the exception of consistently higher standards for parenting. Studies 5 and 6 explored romantic interest in targets that were manipulated to vary in responsiveness and physical attractiveness. These studies found that fear of being single consistently predicted romantic interest in less responsive and less attractive dating targets. Study 7 explored fear of being single during a speed-dating event. We found that fear of being single predicted being less selective in expressing romantic interest but did not predict other daters' romantic interest. Taken together, the present research suggests that fear of being single is a meaningful predictor of settling for less in relationships. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  20. Combined low dose local anesthetics and opioids versus single use ...

    African Journals Online (AJOL)

    2014-09-24

    Sep 24, 2014 ... stay of the patients. Therefore, reducing the side effects associated with intrathecal anesthesia is quite helpful to support better postoperative management. Combined low dose local anesthetics and opioids versus single use of LA for transurethral urological surgery: A meta‑analysis. Y Ding, M Li, L Chen1, ...

  1. Kernel Function Tuning for Single-Layer Neural Networks

    Czech Academy of Sciences Publication Activity Database

    Vidnerová, Petra; Neruda, Roman

    -, accepted 28.11. 2017 (2018) ISSN 2278-0149 R&D Projects: GA ČR GA15-18108S Institutional support: RVO:67985807 Keywords : single-layer neural networks * kernel methods * kernel function * optimisation Subject RIV: IN - Informatics, Computer Science http://www.ijmerr.com/

  2. Double minimum creep of single crystal Ni-base superalloys

    Czech Academy of Sciences Publication Activity Database

    WU, X.; Wollgramm, P.; Somsen, C.; Dlouhý, Antonín; Kostka, A.; Eggeler, G.

    2016-01-01

    Roč. 112, JUN (2016), s. 242-260 ISSN 1359-6454 R&D Projects: GA ČR(CZ) GA14-22834S Institutional support: RVO:68081723 Keywords : Single crystal Ni-base superalloys * Primary creep * Transmission electron microscopy * Dislocations * Stacking fault s Subject RIV: JG - Metallurgy Impact factor: 5.301, year: 2016

  3. Business process support

    Energy Technology Data Exchange (ETDEWEB)

    Carle, Adriana; Fiducia, Daniel [Transportadora de Gas del Sur S.A. (TGS), Buenos Aires (Argentina)

    2005-07-01

    This paper is about the own development of business support software. The developed applications are used to support two business processes: one of them is the process of gas transportation and the other is the natural gas processing. This software has interphases with the ERP SAP, software SCADA and on line gas transportation simulation software. The main functionalities of the applications are: entrance on line real time of clients transport nominations, transport programming, allocation of the clients transport nominations, transport control, measurements, balanced pipeline, allocation of gas volume to the gas processing plants, calculate of product tons processed in each plant and tons of product distributed to clients. All the developed software generates information to the internal staff, regulatory authorities and clients. (author)

  4. Support open access publishing

    DEFF Research Database (Denmark)

    Ekstrøm, Jeannette

    2013-01-01

    Projektet Support Open Access Publishing har til mål at få opdateret Sherpa/Romeo databasen (www.sherpa.ac.uk/romeo) med fagligt relevante, danske tidsskrifter. Projektet skal endvidere undersøge mulighederne for at få udviklet en database, hvor forskere på tværs af relevante tidsskriftsinformati......Projektet Support Open Access Publishing har til mål at få opdateret Sherpa/Romeo databasen (www.sherpa.ac.uk/romeo) med fagligt relevante, danske tidsskrifter. Projektet skal endvidere undersøge mulighederne for at få udviklet en database, hvor forskere på tværs af relevante...... tidsskriftsinformationer (faglig disciplin, BFI niveau, Impact Factor, Open Access) vil kunne danne sig et hurtigt overblik, for derved at kunne træffe et kvalificeret valg om, hvor og hvordan man skal publicere sine forskningsresultater....

  5. RoboWeedSupport

    DEFF Research Database (Denmark)

    Dyrmann, Mads; Nyholm Jørgensen, Rasmus

    2015-01-01

    Information about the weed population in fields is important for determining the optimal herbicides for the fields. A system based on images is presented that can provide support in determining the species and density of the weeds. Firstly, plants are segmented from the soil. Plants that after...... the segmentation are divided in multiple parts are selected manually and a cost image is created by weighting pixels according to their relationship to plant. This relationship is based on the colours of pixels and the weighting of nearby pixels. This cost map is used to find the optimal route that connects...... the plant parts. By using a Support Vector Machine with 18 feature descriptors, suggestions on which plants are present in the images are given. The system is currently able to classify 11 plant species with a precision of 93.0%...

  6. Supporting Transparency between Students

    DEFF Research Database (Denmark)

    Dalsgaard, Christian

    The paper presents the results of a case study that explores the potentials of weblogs and social bookmarking to support transparency in a university course. In the course, groups of students used weblogs and social bookmarking in their work. The objective of the case was to empower students...... by providing them with tools that would be visible to the other students in the course, thus, making students’ ideas, thoughts and questions visible to the other students in the course. The paper concludes that use of digital media for transparency can support empowerment of students and inspiration among...... students in a course, but that the challenge is to create a balance between personal tools and tools for collaborative group work that are also suitable for transparency between students....

  7. Single-electron thermal noise.

    Science.gov (United States)

    Nishiguchi, Katsuhiko; Ono, Yukinori; Fujiwara, Akira

    2014-07-11

    We report the observation of thermal noise in the motion of single electrons in an ultimately small dynamic random access memory (DRAM). The nanometer-scale transistors that compose the DRAM resolve the thermal noise in single-electron motion. A complete set of fundamental tests conducted on this single-electron thermal noise shows that the noise perfectly follows all the aspects predicted by statistical mechanics, which include the occupation probability, the law of equipartition, a detailed balance, and the law of kT/C. In addition, the counting statistics on the directional motion (i.e., the current) of the single-electron thermal noise indicate that the individual electron motion follows the Poisson process, as it does in shot noise.

  8. Single-employer Pension Plans

    Data.gov (United States)

    Pension Benefit Guaranty Corporation — This spreadsheet lists the active single-employer pensions plans insured by PBGC. Plans are identified by name, employer identification number (EIN) and plan number...

  9. Microfluidics for single cell analysis

    DEFF Research Database (Denmark)

    Jensen, Marie Pødenphant

    Isolation and manipulation of single cells have gained an increasing interest from researchers because of the heterogeneity of cells from the same cell culture. Single cell analysis can ensure a better understanding of differences between individual cells and potentially solve a variety of clinical...... problems. In this thesis lab on a chip systems for rare single cell analysis are investigated. The focus was to develop a commercial, disposable device for circulating tumour cell (CTC) analysis. Such a device must be able to separate rare cells from blood samples and subsequently capture the specific...... cells, and simultaneously be fabricated and operated at low costs and be user-friendly. These challenges were addressed through development of two microfluidic devices, one for rare cell isolation based on pinched flow fractionation (PFF) and one for single cell capture based on hydrodynamic trapping...

  10. Single Sign On Internal (SSOi)

    Data.gov (United States)

    Department of Veterans Affairs — Provides single sign-on solution for internal facing VA applications. Allows internal users access to a variety of VA systems and applications using a reduced set of...

  11. COM Support in BETA

    DEFF Research Database (Denmark)

    Madsen, Ole Lehrmann

    1999-01-01

    Component technologies based on binary units of independent production are some of the most important contributions to software architecture and reuse during recent years. Especially the COM technologies and the CORBA standard from the Object Management Group have contributed new and interesting ...... principles for software architecture, and proven to be useful in parctice. In this paper ongoing work with component support in the BETA language is described....

  12. Services Supporting the Customer

    DEFF Research Database (Denmark)

    Gremyr, Ida; Halldorsson, Arni; Hsuan, Juliana

    2017-01-01

    This paper focuses on customer and user experience of advanced service offerings, focusing mechanisms such as e.g. feedback processes as a means to utilise and learn from users’ experiences. The purpose is to understand how servitization changes the constellation of actors in aftermarket value......-organisational) and interaction mechanisms (existing and new) when transitioning to offering more advanced services such as “services supporting customers”....

  13. Supporting shop floor intelligence

    DEFF Research Database (Denmark)

    Carstensen, Peter; Schmidt, Kjeld; Wiil, Uffe Kock

    1999-01-01

    Many manufacturing enterprises are now trying to introduce various forms of flexible work organizations on the shop floor. However, existing computer-based production planning and control systems pose severe obstacles for autonomous working groups and other kinds of shop floor control to become r......-to-day production planning by supporting intelligent and responsible workers in their situated coordination activities on the shop floor....

  14. Allographic Agraphia for Single letters

    OpenAIRE

    Menichelli, Alina; Machetta, Francesca; Zadini, Antonella; Semenza, Carlo

    2012-01-01

    The case is reported of a patient (PS) who, following acute encephalitis with residual occipito-temporal damage, showed a selective deficit in writing cursive letters in isolation, but no difficulty to write cursive-case words and non-words. Notably, he was able to recognize the same allographs he could not write and to produce both single letters and words in print. In addition to this selective single letter writing difficulty, the patient demonstrated an inability to correctly perform a se...

  15. Single nanoparticle tracking spectroscopic microscope

    Science.gov (United States)

    Yang, Haw [Moraga, CA; Cang, Hu [Berkeley, CA; Xu, Cangshan [Berkeley, CA; Wong, Chung M [San Gabriel, CA

    2011-07-19

    A system that can maintain and track the position of a single nanoparticle in three dimensions for a prolonged period has been disclosed. The system allows for continuously imaging the particle to observe any interactions it may have. The system also enables the acquisition of real-time sequential spectroscopic information from the particle. The apparatus holds great promise in performing single molecule spectroscopy and imaging on a non-stationary target.

  16. Single--stranded DNA mycoplasmaviruses

    Energy Technology Data Exchange (ETDEWEB)

    Maniloff, J.; Das, J.; Nowak, J.A.

    1978-01-01

    Two general types of single--stranded DNA bacteriophases have been described, icosahedral virions (e.g., 0X174) and filamentous virions (e.g., M13). Mycoplasmavirus MVL51 appears to represent another type of single--stranded DNA phage, with a genome size close to that of 0X174 and a nonlytic mode of infection like that of filamentous phages. The bullet shaped MVL51 morphology is unlike that of other known phages.

  17. Analysis of single biological cells

    International Nuclear Information System (INIS)

    Watt, Frank

    2002-01-01

    The extraction of elemental information from single cultured cells using nuclear microscopy is an area of great potential because it can provide both quantitative information on the uptake of elements by the cell, and also its elemental response to a wide variety of external stimuli. A recent technique based on nuclear physics technology enables the analysis of single cells down to the parts per million level to be achieved

  18. User and virtual organisation support in EGEE

    CERN Document Server

    Donno, Flavia

    2006-01-01

    User and virtual organisation support in EGEE Providing adequate user support in a grid environment is a very challenging task due to the distributed nature of the grid. The variety of users and the variety of Virtual Organizations (VO) with a wide range of applications in use add further to the challenge. The people asking for support are of various kinds. They can be generic grid beginners, users belonging to a given Virtual Organization and dealing with a specific set of applications, site administrators operating grid services and local computing infrastructures, grid monitoring operators who check the status of the grid and need to contact the specific site to report problems; to this list can be added network specialists and others. Wherever a user is located and whatever the problem experienced is, a user expects from a support infrastructure a given set of services. A non-exhaustive list is the following: a) a single access point for support; b) a portal with a well structured sources of information a...

  19. Bayesian Decision Support

    Science.gov (United States)

    Berliner, M.

    2017-12-01

    Bayesian statistical decision theory offers a natural framework for decision-policy making in the presence of uncertainty. Key advantages of the approach include efficient incorporation of information and observations. However, in complicated settings it is very difficult, perhaps essentially impossible, to formalize the mathematical inputs needed in the approach. Nevertheless, using the approach as a template is useful for decision support; that is, organizing and communicating our analyses. Bayesian hierarchical modeling is valuable in quantifying and managing uncertainty such cases. I review some aspects of the idea emphasizing statistical model development and use in the context of sea-level rise.

  20. Palpability Support Demonstrated

    DEFF Research Database (Denmark)

    Brønsted, Jeppe Rørbæk; Grönvall, Erik; Fors, David

    2007-01-01

    In ubiquitous computing, as more and more devices are embedded into the environment, there is a risk that the user loses the understanding of the system. In normal use this is not always a problem, but when breakdowns occur it is crucial that the user understands the system to be able to handle...... is based on the Active Surfaces concept in which therapists rehabilitate physically and mentally impaired children by means of an activity that stimulates the children both physically and cognitively. In this paper we demonstrate how palpability can be supported in a prototype of the Active Surfaces...

  1. Stennis supports LCROSS sessions

    Science.gov (United States)

    2009-01-01

    Stennis Space Center personnel supported a pair of events marking NASA's Lunar CRater Observation and Sensing Satellite (LCROSS) mission Oct. 9. Stennis participated in daylong activities at the Russell C. Davis Planetarium in Jackson, Miss., and the Kenner (La.) Planetarium Megadome Cinema, providing exhibits, videos and educational activities for students at both sites. The LCROSS mission involved crashing two objects into the moon in order to search for evidence of lunar water ice, an important resource for future sustainable exploration. Pictured at the Kenner planetarium are students from Emily C. Watkins and St. John the Baptist Parish schools at Kenner.

  2. Support or Barrier?

    DEFF Research Database (Denmark)

    Sanden, Guro Refsum; Lønsmann, Dorte

    employees use to cross language boundaries in their everyday work, and, secondly, how these practices relate to top-down language management in the case companies. Our findings show that employees are often dependent on ad hoc and informal solutions in cross- language situations, which leads us......This study offers a critical look at how corporate-level language management influences front-line language practices among employees in three multinational corporations (MNCs) headquartered in Scandinavia. Based on interview and document data, we examine, firstly, what front-line practices...... to a discussion of how a company’s language policy may be seen as both support and a barrier....

  3. CANADA: TRIUMF support

    International Nuclear Information System (INIS)

    Anon.

    1994-01-01

    Citing insufficient levels of foreign contributions, on 22 February Canadian Industry Minister John Manley announced the Federal Government's decision not to support further the KAON accelerator project for the TRIUMF Laboratory in Vancouver. KAON was intended as a five-ring particle 'factory' using KAON's existing 500 MeV cyclotron as injector, producing a variety of beams a hundred times more intense than currently available sources. The mood had been optimistic in the late 1980s when development money came through both from the regional British Columbia administration and from Ottawa

  4. Single VDTA Based Dual Mode Single Input Multioutput Biquad Filter

    Directory of Open Access Journals (Sweden)

    Rajeshwari Pandey

    2016-01-01

    Full Text Available This paper presents a dual mode, single input multioutput (SIMO biquad filter configuration using single voltage differencing transconductance amplifier (VDTA, three capacitors, and a grounded resistor. The proposed topology can be used to synthesize low pass (LP, high pass (HP, and band pass (BP filter functions. It can be configured as voltage mode (VM or current mode (CM structure with appropriate input excitation choice. The angular frequency (ω0 of the proposed structure can be controlled independently of quality factor (Q0. Workability of the proposed biquad configuration is demonstrated through PSPICE simulations using 0.18 μm TSMC CMOS process parameters.

  5. Single particle tracking and single molecule energy transfer

    CERN Document Server

    Bräuchle, Christoph; Michaelis, Jens

    2009-01-01

    Closing a gap in the literature, this handbook gathers all the information on single particle tracking and single molecule energy transfer. It covers all aspects of this hot and modern topic, from detecting virus entry to membrane diffusion, and from protein folding using spFRET to coupled dye systems, as well recent achievements in the field. Throughout, the first-class editors and top international authors present content of the highest quality, making this a must-have for physical chemists, spectroscopists, molecular physicists and biochemists.

  6. Zero-mode waveguide nanophotonic structures for single molecule characterization

    Science.gov (United States)

    Crouch, Garrison M.; Han, Donghoon; Bohn, Paul W.

    2018-05-01

    Single-molecule characterization has become a crucial research tool in the chemical and life sciences, but limitations, such as limited concentration range, inability to control molecular distributions in space, and intrinsic phenomena, such as photobleaching, present significant challenges. Recent developments in non-classical optics and nanophotonics offer promising routes to mitigating these restrictions, such that even low affinity (K D ~ mM) biomolecular interactions can be studied. Here we introduce and review specific nanophotonic devices used to support single molecule studies. Optical nanostructures, such as zero-mode waveguides (ZMWs), are usually fabricated in thin gold or aluminum films and serve to confine the observation volume of optical microspectroscopy to attoliter to zeptoliter volumes. These simple nanostructures allow individual molecules to be isolated for optical and electrochemical analysis, even when the molecules of interest are present at high concentration (µM–mM) in bulk solution. Arrays of ZMWs may be combined with optical probes such as single molecule fluorescence, single molecule fluorescence resonance energy transfer, and fluorescence correlation spectroscopy for distributed analysis of large numbers of single-molecule reactions or binding events in parallel. Furthermore, ZMWs may be used as multifunctional devices, for example by combining optical and electrochemical functions in a single discrete architecture to achieve electrochemical ZMWs. In this review, we will describe the optical properties, fabrication, and applications of ZMWs for single-molecule studies, as well as the integration of ZMWs into systems for chemical and biochemical analysis.

  7. Single Molecule Electronics and Devices

    Science.gov (United States)

    Tsutsui, Makusu; Taniguchi, Masateru

    2012-01-01

    The manufacture of integrated circuits with single-molecule building blocks is a goal of molecular electronics. While research in the past has been limited to bulk experiments on self-assembled monolayers, advances in technology have now enabled us to fabricate single-molecule junctions. This has led to significant progress in understanding electron transport in molecular systems at the single-molecule level and the concomitant emergence of new device concepts. Here, we review recent developments in this field. We summarize the methods currently used to form metal-molecule-metal structures and some single-molecule techniques essential for characterizing molecular junctions such as inelastic electron tunnelling spectroscopy. We then highlight several important achievements, including demonstration of single-molecule diodes, transistors, and switches that make use of electrical, photo, and mechanical stimulation to control the electron transport. We also discuss intriguing issues to be addressed further in the future such as heat and thermoelectric transport in an individual molecule. PMID:22969345

  8. Allographic agraphia for single letters.

    Science.gov (United States)

    Menichelli, Alina; Machetta, Francesca; Zadini, Antonella; Semenza, Carlo

    2012-01-01

    The case is reported of a patient (PS) who, following acute encephalitis with residual occipito-temporal damage, showed a selective deficit in writing cursive letters in isolation, but no difficulty to write cursive-case words and non-words. Notably, he was able to recognize the same allographs he could not write and to produce both single letters and words in print. In addition to this selective single letter writing difficulty, the patient demonstrated an inability to correctly perform a series of imagery tasks for cursive letters. PS's performance may indicate that single letter production requires explicit imagery. Explicit imagery may not be required, instead, when letters have to be produced in the context of a word: letter production in this case may rely on implicit retrieval of well learned scripts in a procedural way.

  9. From joint to single audits

    DEFF Research Database (Denmark)

    Holm, Claus; Thinggaard, Frank

    2018-01-01

    This study analyses audit quality differences between audits by a single big audit firm and joint audits with either one or two big audit firms. We exploit the unique situation in Denmark beginning on 1 January 2005, at which time a long-standing mandatory joint audit system for listed companies...... was replaced by a voluntary joint audit system. First, we report the results of a survey of Danish CFOs’ views on and their experiences with the choice of single or joint audits and their perceptions of audit quality. Second, based on data from the mandatory joint audit abolition year and the following two...... years, we test the audit quality differences using abnormal accruals. Most CFOs perceive that audit quality by a single big four audit firm is the same as it is in joint audits with either one or two big four audit firms. The results of our empirical analysis are in line with the perceptions. We find...

  10. Health Insurance without Single Crossing

    DEFF Research Database (Denmark)

    Boone, Jan; Schottmüller, Christoph

    2017-01-01

    Standard insurance models predict that people with high risks have high insurance coverage. It is empirically documented that people with high income have lower health risks and are better insured. We show that income differences between risk types lead to a violation of single crossing...... in an insurance model where people choose treatment intensity. We analyse different market structures and show the following: If insurers have market power, the violation of single crossing caused by income differences and endogenous treatment choice can explain the empirically observed outcome. Our results do...

  11. Single transverse mode protein laser

    Science.gov (United States)

    Dogru, Itir Bakis; Min, Kyungtaek; Umar, Muhammad; Bahmani Jalali, Houman; Begar, Efe; Conkar, Deniz; Firat Karalar, Elif Nur; Kim, Sunghwan; Nizamoglu, Sedat

    2017-12-01

    Here, we report a single transverse mode distributed feedback (DFB) protein laser. The gain medium that is composed of enhanced green fluorescent protein in a silk fibroin matrix yields a waveguiding gain layer on a DFB resonator. The thin TiO2 layer on the quartz grating improves optical feedback due to the increased effective refractive index. The protein laser shows a single transverse mode lasing at the wavelength of 520 nm with the threshold level of 92.1 μJ/ mm2.

  12. Single liner shipping service design

    DEFF Research Database (Denmark)

    Plum, Christian Edinger Munk; Pisinger, David; Salazar-González, Juan-José

    2014-01-01

    The design of container shipping networks is an important logistics problem, involving assets and operational costs measured in billions of dollars. To guide the optimal deployment of the ships, a single vessel round trip is considered by minimizing operational costs and flowing the best paying...... demand under commercially driven constraints. This paper introduces the Single Liner Shipping Service Design Problem. Arc-flow and path-flow models are presented using state-of-the-art elements from the wide literature on pickup and delivery problems. A Branch-and-Cut-and-Price algorithm is proposed...

  13. The nutritive value of single foods.

    Science.gov (United States)

    Williams, R J; Heffley, J D; Bode, C W

    1971-10-01

    This is an extension of an earlier study in which we found that while commercial "enriched" bread alone would not support the life of weanling rats in a 90-day test, enrichment could be updated at low cost, with the result that rats consuming the improved bread alone lived during the test period and grew seven times as fast. Prominent nutritionists criticized this study on the basis that bread is not eaten alone and that other single foods are likewise deficient. It was stated: "the experiments you performed would have given the same or similar results if you had begun with milk, eggs, meat, or any other food". Skepticism regarding this statement led to experimental trials in which milk, meat, eggs, and several other foods, including breakfast cereals, were fed singly to groups of animals. Eggs proved to be a remarkably complete food, and milk exhibited about the same excellence until the iron deficiency became evident after about two months. "Enriched" breakfast foods and macaroni were highly deficient and could be improved greatly by supplementation.As an outgrowth of this study, we are developing a method of biological testing which is incomparably better for evaluating foods than consulting food composition tables. On the basis of the tabulated data alone one might conclude that "enriched" puffed rice, for example, is only slightly inferior nutritionally to eggs. Our experiments have shown this assumption to be grossly in error.

  14. Single coil bistable, bidirectional micromechanical actuator

    Science.gov (United States)

    Tabat, Ned; Guckel, Henry

    1998-09-15

    Micromechanical actuators capable of bidirectional and bistable operation can be formed on substrates using lithographic processing techniques. Bistable operation of the microactuator is obtained using a single coil and a magnetic core with a gap. A plunger having two magnetic heads is supported for back and forth linear movement with respect to the gap in the magnetic core, and is spring biased to a neutral position in which the two heads are on each side of the gap in the core. The single electrical coil is coupled to the core and is provided with electrical current to attract one of the heads toward the core by reluctance action to drive the plunger to a limit of travel in one direction. The current is then cut off and the plunger returns by spring action toward the gap, whereafter the current is reapplied to the coil to attract the other head of the plunger by reluctance action to drive the plunger to its other limit of travel. This process can be repeated at a time when switching of the actuator is required.

  15. Supporting analyses and assessments

    Energy Technology Data Exchange (ETDEWEB)

    Ohi, J. [National Renewable Energy Lab., Golden, CO (United States)

    1995-09-01

    Supporting analysis and assessments can provide a sound analytic foundation and focus for program planning, evaluation, and coordination, particularly if issues of hydrogen production, distribution, storage, safety, and infrastructure can be analyzed in a comprehensive and systematic manner. The overall purpose of this activity is to coordinate all key analytic tasks-such as technology and market status, opportunities, and trends; environmental costs and benefits; and regulatory constraints and opportunities-within a long-term and systematic analytic foundation for program planning and evaluation. Within this context, the purpose of the project is to help develop and evaluate programmatic pathway options that incorporate near and mid-term strategies to achieve the long-term goals of the Hydrogen Program. In FY 95, NREL will develop a comprehensive effort with industry, state and local agencies, and other federal agencies to identify and evaluate programmatic pathway options to achieve the long-term goals of the Program. Activity to date is reported.

  16. Automated support erection system

    Energy Technology Data Exchange (ETDEWEB)

    Smida, L.; Ondovcin, K.

    1988-03-01

    Describes development of the SPV-1000 roof support feeder, first used in the Cigel coal mine in 1985, and the SPV-1000/u variant which is suitable for use with boring, blasting and shearing methods. The SPV-1000/u moves along a 2D-24 monorail transport system and consists of a segment carrier, manipulator, stabilizer, drive unit, hydraulics unit, control panel, traction unit, control box, rear bogey, limiter bogey, cable bogey, front bogey and assembly unit. Gives details of electrical and hydraulic circuits and main technical parameters: supply voltage 3 x 500 V, 50 Hz; control voltage 24 V; electric motor output 11 kW; hydrostatic transmission; hydraulic pressure 16 MPa; feeder width 800 mm; tractive force 20 kN; speed 0-0.4 m/s. Concludes that use of the SPV-1000/u leads to increased safety and reduced stress and that further refinements will be incorporated into future versions.

  17. Support grows for privatization

    International Nuclear Information System (INIS)

    Anon.

    1996-01-01

    Issues relating to the privatization of Ontario Hydro were discussed in light of the Corporation's first ever indication of being in favour of privatization in its January 26, 1996 submission to the Macdonald Committee, which is studying electric sector reform options for the Ontario government. In the course of the Committee hearings a majority of the interested parties were in favour of some form of privatization, except the labour union, which was, and continues to be, opposed. While welcoming the apparent change in attitude, IPPSO believes that Ontario Hydro's new proposal would, in fact,lessen competition, rather than increase it. It was stated that what Ontario Hydro is asking is to be granted commercial rights, which some experts describe as absolute freedom without meaningful regulation or competition for an indefinite period of time. Details of Ontario Hydro's submission to the Committee, and the basis of the objection of the privatization supporters were explained

  18. [Nutritional support for patients].

    Science.gov (United States)

    Corbee, Ronald Jan; van Kerkhoven, Wim

    2012-06-01

    A good intake of fluids and essential nutrients in the first fourteen days is of vital importance to recuperating animals. Moreover, it is important to encourage cats and dogs to eat after illness or surgery, in order to promote optimal functioning of the gut and the immune system. Enteral nutrition is to be preferred to nasogastric feeding or parenteral nutrition. In the first stage of recovery, during the first 24 to 48 hours, it is important to feed the gut' with nutrients, and thereafter, in the second stage of recovery (after day 3), the calorie intake can be increased. Timely nutritional support with nutraceuticals, such as arginine, glutamine, taurine, long-chain polyunsaturated omega-3 fatty acids, and prebiotic fibres, can considerably shorten the recovery period of cats and dogs after illness or surgery

  19. Support and maneuvering device

    Science.gov (United States)

    Wood, R.L.

    1987-03-23

    A support and maneuvering device includes an elongated flexible inflatable enclosure having a fixed end and a movable end. The movable end is collapsible toward the fixed end to a contracted position when the enclosure is in a noninflated condition. Upon inflation, the movable end is movable away from the fixed end to an extended position. The movable end includes means for mounting an article such as a solar reflector thereon. The device also includes a plurality of position controlling means disposed about the movable end to effect adjusting movement of portions thereof by predetermined amounts and for controlling an angle at which the article disposed at the movable end is oriented. The plurality of position controlling means limits a suitable number degrees of freedom of the movable end for transmitting a steering motion thereto and for controlling the position thereof. 9 figs.

  20. Institutional Support for the Virtual Professor

    Directory of Open Access Journals (Sweden)

    Tom JONES

    2004-01-01

    Full Text Available Academics who hold positions at single-mode, distance education institutions are presently being hampered by an adherence to a long-standing set of protocols (specific office location, face-to-face meetings that were put in place when the conventional post-secondary was the norm. With the advent of a powerful merging of personal computers and the internet, a shift from those protocols to one of support for the virtual professor is in the offing, to the benefit of both the professoriate and the student. A key factor in this shift is the degree and quality of institutional support that will allow these changes to take place. This paper focuses on a number of the key factors that will have to be addressed if this new type of distance education academic is to function effectively.