WorldWideScience

Sample records for single simple global

  1. A Simple Model of Global Aerosol Indirect Effects

    Science.gov (United States)

    Ghan, Steven J.; Smith, Steven J.; Wang, Minghuai; Zhang, Kai; Pringle, Kirsty; Carslaw, Kenneth; Pierce, Jeffrey; Bauer, Susanne; Adams, Peter

    2013-01-01

    Most estimates of the global mean indirect effect of anthropogenic aerosol on the Earth's energy balance are from simulations by global models of the aerosol lifecycle coupled with global models of clouds and the hydrologic cycle. Extremely simple models have been developed for integrated assessment models, but lack the flexibility to distinguish between primary and secondary sources of aerosol. Here a simple but more physically based model expresses the aerosol indirect effect (AIE) using analytic representations of cloud and aerosol distributions and processes. Although the simple model is able to produce estimates of AIEs that are comparable to those from some global aerosol models using the same global mean aerosol properties, the estimates by the simple model are sensitive to preindustrial cloud condensation nuclei concentration, preindustrial accumulation mode radius, width of the accumulation mode, size of primary particles, cloud thickness, primary and secondary anthropogenic emissions, the fraction of the secondary anthropogenic emissions that accumulates on the coarse mode, the fraction of the secondary mass that forms new particles, and the sensitivity of liquid water path to droplet number concentration. Estimates of present-day AIEs as low as 5 W/sq m and as high as 0.3 W/sq m are obtained for plausible sets of parameter values. Estimates are surprisingly linear in emissions. The estimates depend on parameter values in ways that are consistent with results from detailed global aerosol-climate simulation models, which adds to understanding of the dependence on AIE uncertainty on uncertainty in parameter values.

  2. The simple map for a single-null divertor tokamak

    International Nuclear Information System (INIS)

    Punjabi, A.; Verma, A.; Boozer, A.

    1996-01-01

    We present the simple map for a single-null divertor tokamak. The simple map is an area-preserving map based on the idea that magnetic field lines are a single-degree-of-freedom time-dependent Hamiltonian system, and that the basic features of such systems near the X-point are generic. We obtain the properties of this map and the resulting footprints of field lines on the divertor plate. These include the width of the stochastic layer, the edge safety factor, the area of the footprint and the amount of magnetic flux diverted. We give the safety factor profile, the average and median values of strike angles, lengths and the Liapunov exponents. We describe how the effects of magnetic perturbations can be included in the simple map. We show how the map can be applied to the problem of the determination of heat flux on the divertor plate in tokamaks. (Author)

  3. A simple model of global cascades on random networks

    Science.gov (United States)

    Watts, Duncan J.

    2002-04-01

    The origin of large but rare cascades that are triggered by small initial shocks is a phenomenon that manifests itself as diversely as cultural fads, collective action, the diffusion of norms and innovations, and cascading failures in infrastructure and organizational networks. This paper presents a possible explanation of this phenomenon in terms of a sparse, random network of interacting agents whose decisions are determined by the actions of their neighbors according to a simple threshold rule. Two regimes are identified in which the network is susceptible to very large cascadesherein called global cascadesthat occur very rarely. When cascade propagation is limited by the connectivity of the network, a power law distribution of cascade sizes is observed, analogous to the cluster size distribution in standard percolation theory and avalanches in self-organized criticality. But when the network is highly connected, cascade propagation is limited instead by the local stability of the nodes themselves, and the size distribution of cascades is bimodal, implying a more extreme kind of instability that is correspondingly harder to anticipate. In the first regime, where the distribution of network neighbors is highly skewed, it is found that the most connected nodes are far more likely than average nodes to trigger cascades, but not in the second regime. Finally, it is shown that heterogeneity plays an ambiguous role in determining a system's stability: increasingly heterogeneous thresholds make the system more vulnerable to global cascades; but an increasingly heterogeneous degree distribution makes it less vulnerable.

  4. Global-Scale Hydrology: Simple Characterization of Complex Simulation

    Science.gov (United States)

    Koster, Randal D.

    1999-01-01

    Atmospheric general circulation models (AGCMS) are unique and valuable tools for the analysis of large-scale hydrology. AGCM simulations of climate provide tremendous amounts of hydrological data with a spatial and temporal coverage unmatched by observation systems. To the extent that the AGCM behaves realistically, these data can shed light on the nature of the real world's hydrological cycle. In the first part of the seminar, I will describe the hydrological cycle in a typical AGCM, with some emphasis on the validation of simulated precipitation against observations. The second part of the seminar will focus on a key goal in large-scale hydrology studies, namely the identification of simple, overarching controls on hydrological behavior hidden amidst the tremendous amounts of data produced by the highly complex AGCM parameterizations. In particular, I will show that a simple 50-year-old climatological relation (and a recent extension we made to it) successfully predicts, to first order, both the annual mean and the interannual variability of simulated evaporation and runoff fluxes. The seminar will conclude with an example of a practical application of global hydrology studies. The accurate prediction of weather statistics several months in advance would have tremendous societal benefits, and conventional wisdom today points at the use of coupled ocean-atmosphere-land models for such seasonal-to-interannual prediction. Understanding the hydrological cycle in AGCMs is critical to establishing the potential for such prediction. Our own studies show, among other things, that soil moisture retention can lead to significant precipitation predictability in many midlatitude and tropical regions.

  5. Criticality safety validation: Simple geometry, single unit 233U systems

    International Nuclear Information System (INIS)

    Putman, V.L.

    1997-06-01

    Typically used LMITCO criticality safety computational methods are evaluated for suitability when applied to INEEL 233 U systems which reasonably can be modeled as simple-geometry, single-unit systems. Sixty-seven critical experiments of uranium highly enriched in 233 U, including 57 aqueous solution, thermal-energy systems and 10 metal, fast-energy systems, were modeled. These experiments include 41 cylindrical and 26 spherical cores, and 41 reflected and 26 unreflected systems. No experiments were found for intermediate-neutron-energy ranges, or with interstitial non-hydrogenous materials typical of waste systems, mixed 233 U and plutonium, or reflectors such as steel, lead, or concrete. No simple geometry experiments were found with cubic or annular cores, or approximating infinite sea systems. Calculations were performed with various tools and methodologies. Nine cross-section libraries, based on ENDF/B-IV, -V, or -VI.2, or on Hansen-Roach source data, were used with cross-section processing methods of MCNP or SCALE. The k eff calculations were performed with neutral-particle transport and Monte Carlo methods of criticality codes DANT, MCNP 4A, and KENO Va

  6. A simple shear limited, single size, time dependent flocculation model

    Science.gov (United States)

    Kuprenas, R.; Tran, D. A.; Strom, K.

    2017-12-01

    This research focuses on the modeling of flocculation of cohesive sediment due to turbulent shear, specifically, investigating the dependency of flocculation on the concentration of cohesive sediment. Flocculation is important in larger sediment transport models as cohesive particles can create aggregates which are orders of magnitude larger than their unflocculated state. As the settling velocity of each particle is determined by the sediment size, density, and shape, accounting for this aggregation is important in determining where the sediment is deposited. This study provides a new formulation for flocculation of cohesive sediment by modifying the Winterwerp (1998) flocculation model (W98) so that it limits floc size to that of the Kolmogorov micro length scale. The W98 model is a simple approach that calculates the average floc size as a function of time. Because of its simplicity, the W98 model is ideal for implementing into larger sediment transport models; however, the model tends to over predict the dependency of the floc size on concentration. It was found that the modification of the coefficients within the original model did not allow for the model to capture the dependency on concentration. Therefore, a new term within the breakup kernel of the W98 formulation was added. The new formulation results is a single size, shear limited, and time dependent flocculation model that is able to effectively capture the dependency of the equilibrium size of flocs on both suspended sediment concentration and the time to equilibrium. The overall behavior of the new model is explored and showed align well with other studies on flocculation. Winterwerp, J. C. (1998). A simple model for turbulence induced flocculation of cohesive sediment. .Journal of Hydraulic Research, 36(3):309-326.

  7. A simple output voltage control scheme for single phase wavelet ...

    African Journals Online (AJOL)

    DR OKE

    of the wavelet modulated (WM) scheme is that a single synthesis function, derived ... a single-phase H-bridge voltage-source (VS) inverter using MATLAB simulations. ... reconstruction process has been suggested to device a new class of ...

  8. Communicating global climate change using simple indices: an update

    Energy Technology Data Exchange (ETDEWEB)

    Drost, Frank; Karoly, David [University of Melbourne, School of Earth Sciences, Melbourne, VIC (Australia); Braganza, Karl [National Climate Centre, Bureau of Meteorology, Melbourne, VIC (Australia)

    2012-08-15

    Previous studies have shown that there are several indices of global-scale temperature variations, in addition to global-mean surface air temperature, that are useful for distinguishing natural internal climate variations from anthropogenic climate change. Appropriately defined, such indices have the ability to capture spatio-temporal information in a similar manner to optimal fingerprints of climate change. These indices include the contrast between the average temperatures over land and over oceans, the Northern Hemisphere meridional temperature gradient, the temperature contrast between the Northern and Southern Hemisphere and the magnitude of the annual cycle of average temperatures over land. They contain information independent of the global-mean temperature for internal climate variations at decadal time scales and represent different aspects of the climate system, yet they show common responses to anthropogenic climate change. In addition, the ratio of average temperature changes over land to those over the oceans should be nearly constant for transient climate change. Hence, supplementing analysis of global-mean surface temperature with analyses of these indices can strengthen results of attribution studies of causes of observed climate variations. In this study, we extend the previous work by including the last 10 years of observational data and the CMIP3 climate model simulations analysed for the IPCC AR4. We show that observed changes in these indices over the last 10 years provide increased evidence of an anthropogenic influence on climate. We also show the usefulness of these indices for evaluating the performance of climate models in simulating large-scale variability of surface temperature. (orig.)

  9. Simple theory of how spiral galaxies acquire their principal global properties

    International Nuclear Information System (INIS)

    Burstein, D.; Sarazin, C.L.

    1983-01-01

    The strongest correlations among the global properties of spiral galaxies are the power law correlations between luminosity and rotation velocity (the Tully-Fisher relation) and between luminosity and luminous radius. Both of these relations are derived from a single density-radius power-law relation for spiral galaxies, assuming that the total mass-to-luminosity ratio is fixed by the Hubble type of the spiral, and that spirals gain their angular momentum through tidal interactions. The predictions of this simple theory are consistent with the observed luminosity and mass properties of the Hubble type-restricted samples of spiral galaxies studied by Rubin et al. This model suggests that many of the physical properties of spiral galaxies, and of the Hubble sequence, originate before or during the formation of galaxies

  10. A simple formula for determining globally clear skies

    Energy Technology Data Exchange (ETDEWEB)

    Long, C.N.; George, A.T.; Mace, G.G. [Penn State Univ., University Park, PA (United States)] [and others

    1996-04-01

    Surface measurements to serve as {open_quotes}ground truth{close_quotes} are of primary importance in the development of retrieval algorithms using satellite measurements to predict surface irradiance. The most basic algorithms of this type deal with clear sky (i.e., cloudless) top-to-surface shortwave (SW) transfer, serving as a necessary prerequisite towards treating both clear and cloudy conditions. Recently, atmosphere SW cloud forcing to infer the possibility of excess atmospheric absorption (compared with model results) in cloudy atmospheres. The surface component of this ratio relies on inferring the expected clear sky SW irradiance to determine the effects of clouds on the SW energy budget. Solar renewable energy applications make use of clear and cloud fraction climatologies to assess solar radiation resources. All of the above depend to some extent on the identification of globally clear sky conditions and the attendant measurements of downwelling SW irradiance.

  11. Global atmospheric budget of simple monocyclic aromatic compounds

    Directory of Open Access Journals (Sweden)

    D. Cabrera-Perez

    2016-06-01

    Full Text Available The global atmospheric budget and distribution of monocyclic aromatic compounds is estimated, using an atmospheric chemistry general circulation model. Simulation results are evaluated with an ensemble of surface and aircraft observations with the goal of understanding emission, production and removal of these compounds.Anthropogenic emissions provided by the RCP database represent the largest source of aromatics in the model (≃ 23 TgC year−1 and biomass burning from the GFAS inventory the second largest (≃ 5 TgC year−1. The simulated chemical production of aromatics accounts for  ≃ 5 TgC year−1. The atmospheric burden of aromatics sums up to 0.3 TgC. The main removal process of aromatics is photochemical decomposition (≃ 27 TgC  year−1, while wet and dry deposition are responsible for a removal of  ≃ 4 TgC year−1.Simulated mixing ratios at the surface and elsewhere in the troposphere show good spatial and temporal agreement with the observations for benzene, although the model generally underestimates mixing ratios. Toluene is generally well reproduced by the model at the surface, but mixing ratios in the free troposphere are underestimated. Finally, larger discrepancies are found for xylenes: surface mixing ratios are not only overestimated but also a low temporal correlation is found with respect to in situ observations.

  12. Simple test system for single molecule recognition force microscopy

    International Nuclear Information System (INIS)

    Riener, Christian K.; Stroh, Cordula M.; Ebner, Andreas; Klampfl, Christian; Gall, Alex A.; Romanin, Christoph; Lyubchenko, Yuri L.; Hinterdorfer, Peter; Gruber, Hermann J.

    2003-01-01

    We have established an easy-to-use test system for detecting receptor-ligand interactions on the single molecule level using atomic force microscopy (AFM). For this, avidin-biotin, probably the best characterized receptor-ligand pair, was chosen. AFM sensors were prepared containing tethered biotin molecules at sufficiently low surface concentrations appropriate for single molecule studies. A biotin tether, consisting of a 6 nm poly(ethylene glycol) (PEG) chain and a functional succinimide group at the other end, was newly synthesized and covalently coupled to amine-functionalized AFM tips. In particular, PEG 800 diamine was glutarylated, the mono-adduct NH 2 -PEG-COOH was isolated by ion exchange chromatography and reacted with biotin succinimidylester to give biotin-PEG-COOH which was then activated as N-hydroxysuccinimide (NHS) ester to give the biotin-PEG-NHS conjugate which was coupled to the aminofunctionalized AFM tip. The motional freedom provided by PEG allows for free rotation of the biotin molecule on the AFM sensor and for specific binding to avidin which had been adsorbed to mica surfaces via electrostatic interactions. Specific avidin-biotin recognition events were discriminated from nonspecific tip-mica adhesion by their typical unbinding force (∼40 pN at 1.4 nN/s loading rate), unbinding length (<13 nm), the characteristic nonlinear force-distance relation of the PEG linker, and by specific block with excess of free d-biotin. The convenience of the test system allowed to evaluate, and compare, different methods and conditions of tip aminofunctionalization with respect to specific binding and nonspecific adhesion. It is concluded that this system is well suited as calibration or start-up kit for single molecule recognition force microscopy

  13. A Simple But Effective Canonical Dual Theory Unified Algorithm for Global Optimization

    OpenAIRE

    Zhang, Jiapu

    2011-01-01

    Numerical global optimization methods are often very time consuming and could not be applied for high-dimensional nonconvex/nonsmooth optimization problems. Due to the nonconvexity/nonsmoothness, directly solving the primal problems sometimes is very difficult. This paper presents a very simple but very effective canonical duality theory (CDT) unified global optimization algorithm. This algorithm has convergence is proved in this paper. More important, for this CDT-unified algorithm, numerous...

  14. Correlation among electronegativity, cation polarizability, optical basicity and single bond strength of simple oxides

    Energy Technology Data Exchange (ETDEWEB)

    Dimitrov, Vesselin, E-mail: vesselin@uctm.edu [Department of Silicate Technology, University of Chemical Technology and Metallurgy, 8, Kl. Ohridski Blvd., Sofia 1756 (Bulgaria); Komatsu, Takayuki, E-mail: komatsu@mst.nagaokaut.ac.jp [Department of Materials Science and Technology, Nagaoka University of Technology, 1603-1 Kamitomioka-cho, Nagaoka 940-2188 (Japan)

    2012-12-15

    A suitable relationship between free-cation polarizability and electronegativity of elements in different valence states and with the most common coordination numbers has been searched on the basis of the similarity in physical nature of both quantities. In general, the cation polarizability increases with decreasing element electronegativity. A systematic periodic change in the polarizability against the electronegativity has been observed in the isoelectronic series. It has been found that generally the optical basicity increases and the single bond strength of simple oxides decreases with decreasing the electronegativity. The observed trends have been discussed on the basis of electron donation ability of the oxide ions and type of chemical bonding in simple oxides. - Graphical abstract: This figure shows the single bond strength of simple oxides as a function of element electronegativity. A remarkable correlation exists between these independently obtained quantities. High values of electronegativity correspond to high values of single bond strength and vice versa. It is obvious that the observed trend in this figure is closely related to the type of chemical bonding in corresponding oxide. Highlights: Black-Right-Pointing-Pointer A suitable relationship between free-cation polarizability and electronegativity of elements was searched. Black-Right-Pointing-Pointer The cation polarizability increases with decreasing element electronegativity. Black-Right-Pointing-Pointer The single bond strength of simple oxides decreases with decreasing the electronegativity. Black-Right-Pointing-Pointer The observed trends were discussed on the basis of type of chemical bonding in simple oxides.

  15. Single Spore Isolation as a Simple and Efficient Technique to obtain fungal pure culture

    Science.gov (United States)

    Noman, E.; Al-Gheethi, AA; Rahman, N. K.; Talip, B.; Mohamed, R.; H, N.; Kadir, O. A.

    2018-04-01

    The successful identification of fungi by phenotypic methods or molecular technique depends mainly on the using an advanced technique for purifying the isolates. The most efficient is the single spore technique due to the simple requirements and the efficiency in preventing the contamination by yeast, mites or bacteria. The method described in the present work is depends on the using of a light microscope to transfer one spore into a new culture medium. The present work describes a simple and efficient procedure for single spore isolation to purify of fungi recovered from the clinical wastes.

  16. Global solvability of the differential operators non-invariants on semi-simple Lie groups

    International Nuclear Information System (INIS)

    El Hussein, K.

    1991-09-01

    Let G be a connected semi-simple Lie group with finite centre and let G=KAN be the Iwasawa decomposition of G. Let P be a differential operator on G, which is right invariant by the sub-group AN and left invariant by the sub-group K. In this paper, we give a necessary and sufficient condition for the global solvability of P on G. (author). 5 refs

  17. A simple optical fiber device for quantitative fluorescence microscopy of single living cells

    NARCIS (Netherlands)

    van Graft, M.; van Graft, Marja; Oosterhuis, B.; Oosterhuis, Bernard; van der Werf, Kees; de Grooth, B.G.; Greve, Jan

    1993-01-01

    simple and relatively inexpensive system is described for obtaining quantitative fluorescence measurements on single living cells loaded with a fluorescent probe to study cell physiological processes. The light emitted from the fluorescent cells is captured by and transported through an optical

  18. A simple optical fiber device for quantitative fluorescence microscopy of single living cells

    OpenAIRE

    van Graft, M.; van Graft, Marja; Oosterhuis, B.; Oosterhuis, Bernard; van der Werf, Kees; de Grooth, B.G.; Greve, Jan

    1993-01-01

    simple and relatively inexpensive system is described for obtaining quantitative fluorescence measurements on single living cells loaded with a fluorescent probe to study cell physiological processes. The light emitted from the fluorescent cells is captured by and transported through an optical fiber. After passage through appropriate filters the light is measured using a photomultiplier tube. The optical fiber is mounted in one of the microscope outlets. Signals derived from the photomultipl...

  19. Experimental demonstration of a simple displacement sensor based on a bent single-mode–multimode–single-mode fiber structure

    International Nuclear Information System (INIS)

    Wu, Qiang; Semenova, Yuliya; Wang, Pengfei; Hatta, Agus Muhamad; Farrell, Gerald

    2011-01-01

    A simple displacement sensor based on a bent single-mode–multimode–single-mode (SMS) fiber structure is proposed and experimentally investigated. The sensor offers a wider displacement range, not limited by the risk of fiber breakage, as well as a three-fold increase in displacement sensitivity by comparison with a straight SMS structure sensor. This sensor can be interrogated by either an optical spectral analyzer (OSA) or a ratiometric interrogation system: (1) if interrogated by an OSA assuming a resolution of 1 pm, it has a sensitivity of 28.2 nm for a displacement measurement range from 0 to 280 µm; (2) if interrogated by a ratiometric interrogation system, it has worst and best case resolutions of 556 and 38 nm, respectively, for a displacement measurement range from 0 to 520 µm

  20. Simple vs. Complex Carbohydrate Dietary Patterns and the Global Overweight and Obesity Pandemic.

    Science.gov (United States)

    Ferretti, Fabrizio; Mariani, Michele

    2017-10-04

    Nowadays, obesity and being overweight are among the major global health concerns. Many, diet-related diseases impose high tangible and intangible costs, and threaten the sustainability of health-care systems worldwide. In this study, we model, at the macroeconomic level, the impact of energy intake from different types of carbohydrates on the population's BMI (body mass index). We proceed in three steps. First, we develop a framework to analyse both the consumption choices between simple and complex carbohydrates and the effects of these choices on people health conditions. Second, we collect figures for 185 countries (over the period 2012-2014) regarding the shares of simple (sugar and sweetener) and complex (cereal) carbohydrates in each country's total dietary energy supply. Third, we use regression techniques to: (1) estimate the impact of these shares on the country's prevalence of obesity and being overweight; (2) compute for each country an indicator of dietary pattern based on the ratio between simple and complex carbohydrates, weighted by their estimated effects on the prevalence of obesity and being overweight; and (3) measure the elasticity of the prevalence of obesity and being overweight with respect to changes in both carbohydrate dietary pattern and income per capita. We find that unhealthy eating habits and the associated prevalence of excessive body fat accumulation tend to behave as a 'normal good' in low, medium- and high-HDI (Human Development Index) countries, but as an 'inferior good' in very high-HDI countries.

  1. Calibration of a simple and a complex model of global marine biogeochemistry

    Science.gov (United States)

    Kriest, Iris

    2017-11-01

    The assessment of the ocean biota's role in climate change is often carried out with global biogeochemical ocean models that contain many components and involve a high level of parametric uncertainty. Because many data that relate to tracers included in a model are only sparsely observed, assessment of model skill is often restricted to tracers that can be easily measured and assembled. Examination of the models' fit to climatologies of inorganic tracers, after the models have been spun up to steady state, is a common but computationally expensive procedure to assess model performance and reliability. Using new tools that have become available for global model assessment and calibration in steady state, this paper examines two different model types - a complex seven-component model (MOPS) and a very simple four-component model (RetroMOPS) - for their fit to dissolved quantities. Before comparing the models, a subset of their biogeochemical parameters has been optimised against annual-mean nutrients and oxygen. Both model types fit the observations almost equally well. The simple model contains only two nutrients: oxygen and dissolved organic phosphorus (DOP). Its misfit and large-scale tracer distributions are sensitive to the parameterisation of DOP production and decay. The spatio-temporal decoupling of nitrogen and oxygen, and processes involved in their uptake and release, renders oxygen and nitrate valuable tracers for model calibration. In addition, the non-conservative nature of these tracers (with respect to their upper boundary condition) introduces the global bias (fixed nitrogen and oxygen inventory) as a useful additional constraint on model parameters. Dissolved organic phosphorus at the surface behaves antagonistically to phosphate, and suggests that observations of this tracer - although difficult to measure - may be an important asset for model calibration.

  2. A new simple parameterization of daily clear-sky global solar radiation including horizon effects

    International Nuclear Information System (INIS)

    Lopez, Gabriel; Javier Batlles, F.; Tovar-Pescador, Joaquin

    2007-01-01

    Estimation of clear-sky global solar radiation is usually an important previous stage for calculating global solar radiation under all sky conditions. This is, for instance, a common procedure to derive incoming solar radiation from remote sensing or by using digital elevation models. In this work, we present a new model to calculate daily values of clear-sky global solar irradiation. The main goal is the simple parameterization in terms of atmospheric temperature and relative humidity, Angstroem's turbidity coefficient, ground albedo and site elevation, including a factor to take into account horizon obstructions. This allows us to obtain estimates even though a free horizon is not present as is the case of mountainous locations. Comparisons of calculated daily values with measured data show that this model is able to provide a good level of accurate estimates using either daily or mean monthly values of the input parameters. This new model has also been shown to improve daily estimates against those obtained using the clear-sky model from the European Solar Radiation Atlas and other accurate parameterized daily irradiation models. The introduction of Angstroem's turbidity coefficient and ground albedo should allow us to use the increasing worldwide aerosol information available and to consider those sites affected by snow covers in an easy and fast way. In addition, the proposed model is intended to be a useful tool to select clear-sky conditions

  3. A simple technique of intraocular lenses explantation for single-piece foldable lenses

    Directory of Open Access Journals (Sweden)

    Arup Bhaumik

    2017-01-01

    Full Text Available Foldable intraocular lenses (IOLs are most commonly used in modern-day cataract surgery. Explantation of these IOLs is not frequently encountered, but sometimes extreme situations may demand the same. Commonly explantation is achieved by bisecting the IOL inside the anterior chamber with a cutter and delivering the pieces out one by one. This may require corneal wound extension with associated damage and endothelial loss leading to visual deterioration. We devised a simple, innovative IOL explantation technique utilizing a modified Alcon A cartridge and snare. This can successfully refold the IOL to be explanted inside the eye and deliver it out through the same wound. The device has limitations with very thick optic lenses, multipiece, and silicon IOLs. In conclusion, we describe a simple, innovative, and reproducible technique to explant almost any single piece IOL without compromising the original surgery and yielding very satisfactory outcomes.

  4. Large-scale single-chirality separation of single-wall carbon nanotubes by simple gel chromatography

    Science.gov (United States)

    Liu, Huaping; Nishide, Daisuke; Tanaka, Takeshi; Kataura, Hiromichi

    2011-01-01

    Monostructured single-wall carbon nanotubes (SWCNTs) are important in both scientific research and electronic and biomedical applications; however, the bulk separation of SWCNTs into populations of single-chirality nanotubes remains challenging. Here we report a simple and effective method for the large-scale chirality separation of SWCNTs using a single-surfactant multicolumn gel chromatography method utilizing one surfactant and a series of vertically connected gel columns. This method is based on the structure-dependent interaction strength of SWCNTs with an allyl dextran-based gel. Overloading an SWCNT dispersion on the top column results in the adsorption sites of the column becoming fully occupied by the nanotubes that exhibit the strongest interaction with the gel. The unbound nanotubes flow through to the next column, and the nanotubes with the second strongest interaction with the gel are adsorbed in this stage. In this manner, 13 different (n, m) species were separated. Metallic SWCNTs were finally collected as unbound nanotubes because they exhibited the lowest interaction with the gel. PMID:21556063

  5. Addressing challenges in single species assessments via a simple state-space assessment model

    DEFF Research Database (Denmark)

    Nielsen, Anders

    Single-species and age-structured fish stock assessments still remains the main tool for managing fish stocks. A simple state-space assessment model is presented as an alternative to (semi) deterministic procedures and the full parametric statistical catch at age models. It offers a solution...... to some of the key challenges of these models. Compared to the deterministic procedures it solves a list of problems originating from falsely assuming that age classified catches are known without errors and allows quantification of uncertainties of estimated quantities of interest. Compared to full...

  6. Simple and efficient absorption filter for single photons from a cold atom quantum memory.

    Science.gov (United States)

    Stack, Daniel T; Lee, Patricia J; Quraishi, Qudsia

    2015-03-09

    The ability to filter unwanted light signals is critical to the operation of quantum memories based on neutral atom ensembles. Here we demonstrate an efficient frequency filter which uses a vapor cell filled with (85)Rb and a buffer gas to attenuate both residual laser light and noise photons by nearly two orders of magnitude with little loss to the single photons associated with our cold (87)Rb quantum memory. This simple, passive filter provides an additional 18 dB attenuation of our pump laser and erroneous spontaneous emissions for every 1 dB loss of the single photon signal. We show that the addition of a frequency filter increases the non-classical correlations and the retrieval efficiency of our quantum memory by ≈ 35%.

  7. A simple route to the synthesis of single crystalline copper metagermanate nanowires

    Energy Technology Data Exchange (ETDEWEB)

    Pei, L.Z., E-mail: lzpei@ahut.edu.cn [School of Materials Science and Engineering, Institute of Molecular Engineering and Applied Chemistry, Key Lab of Materials Science and Processing of Anhui Province, Anhui University of Technology, Ma' anshan, Anhui 243002 (China); Zhao, H.S. [School of Materials Science and Engineering, Institute of Molecular Engineering and Applied Chemistry, Key Lab of Materials Science and Processing of Anhui Province, Anhui University of Technology, Ma' anshan, Anhui 243002 (China); Tan, W. [Henkel Huawei Electronics Co. Ltd., Lian' yungang, Jiangsu 222006 (China); Yu, H.Y. [School of Materials Science and Engineering, Institute of Molecular Engineering and Applied Chemistry, Key Lab of Materials Science and Processing of Anhui Province, Anhui University of Technology, Ma' anshan, Anhui 243002 (China); Chen, Y.W. [Department of Materials Science, Fudan University, Shanghai 200433 (China); Zhang Qianfeng; Fan, C.G. [School of Materials Science and Engineering, Institute of Molecular Engineering and Applied Chemistry, Key Lab of Materials Science and Processing of Anhui Province, Anhui University of Technology, Ma' anshan, Anhui 243002 (China)

    2009-12-15

    Single crystalline copper metagermanate (CuGeO{sub 3}) nanowires with the diameter of 30-300 nm and length of longer than 100 {mu}m have been prepared by a simple hydrothermal deposition route. X-ray diffraction (XRD), selected area electron diffraction (SAED), high-resolution transmission electron microscopy (HRTEM) and Raman analyses confirm that the nanowires are orthorhombic single crystals with a main growth direction along <101>. Room temperature photoluminescence (PL) measurement shows a strong blue emission peak at 442 nm with a broad emission band. The blue emission may be ascribed to radiative recombination of oxygen vacancies and oxygen-germanium vacancies. The formation process of CuGeO{sub 3} nanowires is also discussed.

  8. A simple global carbon and energy coupled cycle model for global warming simulation: sensitivity to the light saturation effect

    International Nuclear Information System (INIS)

    Ichii, Kazuhito; Murakami, Kazutaka; Mukai, Toshikazu; Yamaguchi, Yasushi; Ogawa, Katsuro

    2003-01-01

    A simple Earth system model, the Four-Spheres Cycle of Energy and Mass (4-SCEM) model, has been developed to simulate global warming due to anthropogenic CO 2 emission. The model consists of the Atmosphere-Earth Heat Cycle (AEHC) model, the Four Spheres Carbon Cycle (4-SCC) model, and their feedback processes. The AEHC model is a one-dimensional radiative convective model, which includes the greenhouse effect of CO 2 and H 2 O, and one cloud layer. The 4-SCC model is a box-type carbon cycle model, which includes biospheric CO 2 fertilization, vegetation area variation, the vegetation light saturation effect and the HILDA oceanic carbon cycle model. The feedback processes between carbon cycle and climate considered in the model are temperature dependencies of water vapor content, soil decomposition and ocean surface chemistry. The future status of the global carbon cycle and climate was simulated up to the year 2100 based on the 'business as usual' (IS92a) emission scenario, followed by a linear decline in emissions to zero in the year 2200. The atmospheric CO 2 concentration reaches 645 ppmv in 2100 and a peak of 760 ppmv approximately in the year 2170, and becomes a steady state with 600 ppmv. The projected CO 2 concentration was lower than those of the past carbon cycle studies, because we included the light saturation effect of vegetation. The sensitivity analysis showed that uncertainties derived from the light saturation effect of vegetation and land use CO 2 emissions were the primary cause of uncertainties in projecting future CO 2 concentrations. The climate feedback effects showed rather small sensitivities compared with the impacts of those two effects. Satellite-based net primary production trends analyses can somewhat decrease the uncertainty in quantifying CO 2 emissions due to land use changes. On the other hand, as the estimated parameter in vegetation light saturation was poorly constrained, we have to quantify and constrain the effect more

  9. A simple and efficient algorithm to estimate daily global solar radiation from geostationary satellite data

    International Nuclear Information System (INIS)

    Lu, Ning; Qin, Jun; Yang, Kun; Sun, Jiulin

    2011-01-01

    Surface global solar radiation (GSR) is the primary renewable energy in nature. Geostationary satellite data are used to map GSR in many inversion algorithms in which ground GSR measurements merely serve to validate the satellite retrievals. In this study, a simple algorithm with artificial neural network (ANN) modeling is proposed to explore the non-linear physical relationship between ground daily GSR measurements and Multi-functional Transport Satellite (MTSAT) all-channel observations in an effort to fully exploit information contained in both data sets. Singular value decomposition is implemented to extract the principal signals from satellite data and a novel method is applied to enhance ANN performance at high altitude. A three-layer feed-forward ANN model is trained with one year of daily GSR measurements at ten ground sites. This trained ANN is then used to map continuous daily GSR for two years, and its performance is validated at all 83 ground sites in China. The evaluation result demonstrates that this algorithm can quickly and efficiently build the ANN model that estimates daily GSR from geostationary satellite data with good accuracy in both space and time. -- Highlights: → A simple and efficient algorithm to estimate GSR from geostationary satellite data. → ANN model fully exploits both the information from satellite and ground measurements. → Good performance of the ANN model is comparable to that of the classical models. → Surface elevation and infrared information enhance GSR inversion.

  10. A simple integrated assessment approach to global change simulation and evaluation

    Science.gov (United States)

    Ogutu, Keroboto; D'Andrea, Fabio; Ghil, Michael

    2016-04-01

    We formulate and study the Coupled Climate-Economy-Biosphere (CoCEB) model, which constitutes the basis of our idealized integrated assessment approach to simulating and evaluating global change. CoCEB is composed of a physical climate module, based on Earth's energy balance, and an economy module that uses endogenous economic growth with physical and human capital accumulation. A biosphere model is likewise under study and will be coupled to the existing two modules. We concentrate on the interactions between the two subsystems: the effect of climate on the economy, via damage functions, and the effect of the economy on climate, via a control of the greenhouse gas emissions. Simple functional forms of the relation between the two subsystems permit simple interpretations of the coupled effects. The CoCEB model is used to make hypotheses on the long-term effect of investment in emission abatement, and on the comparative efficacy of different approaches to abatement, in particular by investing in low carbon technology, in deforestation reduction or in carbon capture and storage (CCS). The CoCEB model is very flexible and transparent, and it allows one to easily formulate and compare different functional representations of climate change mitigation policies. Using different mitigation measures and their cost estimates, as found in the literature, one is able to compare these measures in a coherent way.

  11. Simple vs. Complex Carbohydrate Dietary Patterns and the Global Overweight and Obesity Pandemic

    Directory of Open Access Journals (Sweden)

    Fabrizio Ferretti

    2017-10-01

    Full Text Available Nowadays, obesity and being overweight are among the major global health concerns. Many, diet-related diseases impose high tangible and intangible costs, and threaten the sustainability of health-care systems worldwide. In this study, we model, at the macroeconomic level, the impact of energy intake from different types of carbohydrates on the population’s BMI (body mass index. We proceed in three steps. First, we develop a framework to analyse both the consumption choices between simple and complex carbohydrates and the effects of these choices on people health conditions. Second, we collect figures for 185 countries (over the period 2012–2014 regarding the shares of simple (sugar and sweetener and complex (cereal carbohydrates in each country’s total dietary energy supply. Third, we use regression techniques to: (1 estimate the impact of these shares on the country’s prevalence of obesity and being overweight; (2 compute for each country an indicator of dietary pattern based on the ratio between simple and complex carbohydrates, weighted by their estimated effects on the prevalence of obesity and being overweight; and (3 measure the elasticity of the prevalence of obesity and being overweight with respect to changes in both carbohydrate dietary pattern and income per capita. We find that unhealthy eating habits and the associated prevalence of excessive body fat accumulation tend to behave as a ‘normal good’ in low, medium- and high-HDI (Human Development Index countries, but as an ‘inferior good’ in very high-HDI countries.

  12. A simple and rapid method for high-resolution visualization of single-ion tracks

    Directory of Open Access Journals (Sweden)

    Masaaki Omichi

    2014-11-01

    Full Text Available Prompt determination of spatial points of single-ion tracks plays a key role in high-energy particle induced-cancer therapy and gene/plant mutations. In this study, a simple method for the high-resolution visualization of single-ion tracks without etching was developed through the use of polyacrylic acid (PAA-N, N’-methylene bisacrylamide (MBAAm blend films. One of the steps of the proposed method includes exposure of the irradiated films to water vapor for several minutes. Water vapor was found to promote the cross-linking reaction of PAA and MBAAm to form a bulky cross-linked structure; the ion-track scars were detectable at a nanometer scale by atomic force microscopy. This study demonstrated that each scar is easily distinguishable, and the amount of generated radicals of the ion tracks can be estimated by measuring the height of the scars, even in highly dense ion tracks. This method is suitable for the visualization of the penumbra region in a single-ion track with a high spatial resolution of 50 nm, which is sufficiently small to confirm that a single ion hits a cell nucleus with a size ranging between 5 and 20 μm.

  13. A simple and rapid method for high-resolution visualization of single-ion tracks

    Energy Technology Data Exchange (ETDEWEB)

    Omichi, Masaaki [Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Osaka 565-0871 (Japan); Center for Collaborative Research, Anan National College of Technology, Anan, Tokushima 774-0017 (Japan); Choi, Wookjin; Sakamaki, Daisuke; Seki, Shu, E-mail: seki@chem.eng.osaka-u.ac.jp [Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Osaka 565-0871 (Japan); Tsukuda, Satoshi [Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Miyagi 980-8577 (Japan); Sugimoto, Masaki [Japan Atomic Energy Agency, Takasaki Advanced Radiation Research Institute, Gunma, Gunma 370-1292 (Japan)

    2014-11-15

    Prompt determination of spatial points of single-ion tracks plays a key role in high-energy particle induced-cancer therapy and gene/plant mutations. In this study, a simple method for the high-resolution visualization of single-ion tracks without etching was developed through the use of polyacrylic acid (PAA)-N, N’-methylene bisacrylamide (MBAAm) blend films. One of the steps of the proposed method includes exposure of the irradiated films to water vapor for several minutes. Water vapor was found to promote the cross-linking reaction of PAA and MBAAm to form a bulky cross-linked structure; the ion-track scars were detectable at a nanometer scale by atomic force microscopy. This study demonstrated that each scar is easily distinguishable, and the amount of generated radicals of the ion tracks can be estimated by measuring the height of the scars, even in highly dense ion tracks. This method is suitable for the visualization of the penumbra region in a single-ion track with a high spatial resolution of 50 nm, which is sufficiently small to confirm that a single ion hits a cell nucleus with a size ranging between 5 and 20 μm.

  14. Computational quantum chemistry for single Heisenberg spin couplings made simple: Just one spin flip required

    International Nuclear Information System (INIS)

    Mayhall, Nicholas J.; Head-Gordon, Martin

    2014-01-01

    We highlight a simple strategy for computing the magnetic coupling constants, J, for a complex containing two multiradical centers. On the assumption that the system follows Heisenberg Hamiltonian physics, J is obtained from a spin-flip electronic structure calculation where only a single electron is excited (and spin-flipped), from the single reference with maximum S ^ z , M, to the M − 1 manifold, regardless of the number of unpaired electrons, 2M, on the radical centers. In an active space picture involving 2M orbitals, only one β electron is required, together with only one α hole. While this observation is extremely simple, the reduction in the number of essential configurations from exponential in M to only linear provides dramatic computational benefits. This (M, M − 1) strategy for evaluating J is an unambiguous, spin-pure, wave function theory counterpart of the various projected broken symmetry density functional theory schemes, and likewise gives explicit energies for each possible spin-state that enable evaluation of properties. The approach is illustrated on five complexes with varying numbers of unpaired electrons, for which one spin-flip calculations are used to compute J. Some implications for further development of spin-flip methods are discussed

  15. Simple immunoglobulin G sensor based on thin core single-mode fiber

    Science.gov (United States)

    Zheng, Yingfang; Lang, Tingting; Shen, Tingting; Shen, Changyu

    2018-03-01

    In this paper, a simple fiber biosensor (FOB) for immunoglobulin G (IgG) detection is designed and experimentally verified. The FOB is constructed by a 20 mm long thin core single-mode fiber (TCSMF) sandwiched between two single-mode optical fibers (SMFs). First, the refractive index (RI) sensitivity of the fiber structures is calculated by the beam propagation method. The refractive index sensing experiment is performed using different concentrations of glycerol solutions, and the experimental results are mostly consistent with the simulation predictions. The experimental RI sensitivity increases with the surrounding RI and reaches 82.7 nm/RIU. Then the surface of the FOB is functionalized by APTES for covalent bonding. The human IgG and goat anti-human IgG are chosen as a bioconjugated pair to examine the bio-sensing effectiveness of this FOB. The sensitivity of IgG detection is determined to be 10.4 nm/(mg/ml). And the serum IgG concentration in normal adults lies within the range of 6-16 mg/ml (Worsfold et al., 1985), so the sensor is applicable to human IgG monitoring. The specificity of the FOB is also verified by a contrast experiment conducted using rabbit immunoglobulin G. The proposed FOB is simple, low loss, cost-effective, and can be used for various biological and chemical applications.

  16. Inversion of self-potential anomalies caused by simple-geometry bodies using global optimization algorithms

    International Nuclear Information System (INIS)

    Göktürkler, G; Balkaya, Ç

    2012-01-01

    Three naturally inspired meta-heuristic algorithms—the genetic algorithm (GA), simulated annealing (SA) and particle swarm optimization (PSO)—were used to invert some of the self-potential (SP) anomalies originated by some polarized bodies with simple geometries. Both synthetic and field data sets were considered. The tests with the synthetic data comprised of the solutions with both noise-free and noisy data; in the tests with the field data some SP anomalies observed over a copper belt (India), graphite deposits (Germany) and metallic sulfide (Turkey) were inverted. The model parameters included the electric dipole moment, polarization angle, depth, shape factor and origin of the anomaly. The estimated parameters were compared with those from previous studies using various optimization algorithms, mainly least-squares approaches, on the same data sets. During the test studies the solutions by GA, PSO and SA were characterized as being consistent with each other; a good starting model was not a requirement to reach the global minimum. It can be concluded that the global optimization algorithms considered in this study were able to yield compatible solutions with those from widely used local optimization algorithms. (paper)

  17. Description and validation of the Simple, Efficient, Dynamic, Global, Ecological Simulator (SEDGES v.1.0)

    Science.gov (United States)

    Paiewonsky, Pablo; Elison Timm, Oliver

    2018-03-01

    In this paper, we present a simple dynamic global vegetation model whose primary intended use is auxiliary to the land-atmosphere coupling scheme of a climate model, particularly one of intermediate complexity. The model simulates and provides important ecological-only variables but also some hydrological and surface energy variables that are typically either simulated by land surface schemes or else used as boundary data input for these schemes. The model formulations and their derivations are presented here, in detail. The model includes some realistic and useful features for its level of complexity, including a photosynthetic dependency on light, full coupling of photosynthesis and transpiration through an interactive canopy resistance, and a soil organic carbon dependence for bare-soil albedo. We evaluate the model's performance by running it as part of a simple land surface scheme that is driven by reanalysis data. The evaluation against observational data includes net primary productivity, leaf area index, surface albedo, and diagnosed variables relevant for the closure of the hydrological cycle. In this setup, we find that the model gives an adequate to good simulation of basic large-scale ecological and hydrological variables. Of the variables analyzed in this paper, gross primary productivity is particularly well simulated. The results also reveal the current limitations of the model. The most significant deficiency is the excessive simulation of evapotranspiration in mid- to high northern latitudes during their winter to spring transition. The model has a relative advantage in situations that require some combination of computational efficiency, model transparency and tractability, and the simulation of the large-scale vegetation and land surface characteristics under non-present-day conditions.

  18. A simple analytical model of single-event upsets in bulk CMOS

    Energy Technology Data Exchange (ETDEWEB)

    Sogoyan, Armen V.; Chumakov, Alexander I.; Smolin, Anatoly A., E-mail: aasmol@spels.ru; Ulanova, Anastasia V.; Boruzdina, Anna B.

    2017-06-01

    During the last decade, multiple new methods of single event upset (SEU) rate prediction for aerospace systems have been proposed. Despite different models and approaches being employed in these methods, they all share relatively high usage complexity and require information about a device that is not always available to an end user. This work presents an alternative approach to estimating SEU cross-section as a function of linear energy transfer (LET) that can be further developed into a method of SEU rate prediction. The goal is to propose a simple, yet physics-based, approach with just two parameters that can be used even in situations when only a process node of the device is known. The developed approach is based on geometrical interpretation of SEU cross-section and an analytical solution to the diffusion problem obtained for a simplified IC topology model. A good fit of the model to the experimental data encompassing 7 generations of SRAMs is demonstrated.

  19. Simple and Reproducible Sample Preparation for Single-Shot Phosphoproteomics with High Sensitivity

    DEFF Research Database (Denmark)

    Jersie-Christensen, Rosa R.; Sultan, Abida; Olsen, Jesper V

    2016-01-01

    The traditional sample preparation workflow for mass spectrometry (MS)-based phosphoproteomics is time consuming and usually requires multiple steps, e.g., lysis, protein precipitation, reduction, alkylation, digestion, fractionation, and phosphopeptide enrichment. Each step can introduce chemical...... artifacts, in vitro protein and peptide modifications, and contaminations. Those often result in sample loss and affect the sensitivity, dynamic range and accuracy of the mass spectrometric analysis. Here we describe a simple and reproducible phosphoproteomics protocol, where lysis, denaturation, reduction......, and alkylation are performed in a single step, thus reducing sample loss and increasing reproducibility. Moreover, unlike standard cell lysis procedures the cell harvesting is performed at high temperatures (99 °C) and without detergents and subsequent need for protein precipitation. Phosphopeptides are enriched...

  20. A Simple Setup to Perform 3D Locomotion Tracking in Zebrafish by Using a Single Camera

    Directory of Open Access Journals (Sweden)

    Gilbert Audira

    2018-02-01

    Full Text Available Generally, the measurement of three-dimensional (3D swimming behavior in zebrafish relies on commercial software or requires sophisticated scripts, and depends on more than two cameras to capture the video. Here, we establish a simple and economic apparatus to detect 3D locomotion in zebrafish, which involves a single camera capture system that records zebrafish movement in a specially designed water tank with a mirror tilted at 45 degrees. The recorded videos are analyzed using idTracker, while spatial positions are calibrated by ImageJ software and 3D trajectories are plotted by Origin 9.1 software. This easy setting allowed scientists to track 3D swimming behavior of multiple zebrafish with low cost and precise spatial position, showing great potential for fish behavioral research in the future.

  1. Simple extraction-solvothermal synthesis of single-crystalline silver microplates

    Energy Technology Data Exchange (ETDEWEB)

    You, Ting; Sun, Sixiu; Song, Xinyu; Xu, Shuling [Department of Chemistry and Chemical Engineering, Shandong University (China)

    2009-08-15

    Single-crystalline silver microplates, with average edge length of about 1.5{mu}m and thickness of 100 nm, have been synthesized by a simple extraction-solvothermal method. Samples were characterized in detail by X-ray diffraction (XRD), field-emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM) and High-resolution transmission electron microscopy (HRTEM) technologies. Extractant primary amine N1923 can also act as reducing agent. It has been found that microstructure of the silver can be controlled by the n-octanol during the solvothermal treatment. Based on a series of experimental analysis, the possible formation mechanism of these microplates was discussed briefly. (copyright 2009 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  2. Single crystalline ZnO nanorods grown by a simple hydrothermal process

    Energy Technology Data Exchange (ETDEWEB)

    Pei, L.Z., E-mail: lzpei1977@163.com [School of Materials Science and Engineering, Institute of Molecular Engineering and Applied Chemistry, Key Lab of Materials Science and Processing of Anhui Province, Anhui University of Technology, Ma' anshan, Anhui 243002 (China); Zhao, H.S. [School of Materials Science and Engineering, Institute of Molecular Engineering and Applied Chemistry, Key Lab of Materials Science and Processing of Anhui Province, Anhui University of Technology, Ma' anshan, Anhui 243002 (China); Tan, W. [Henkel Huawei Electronics Co. Ltd., Lian' yungang, Jiangsu 222006 (China); Yu, H.Y. [School of Materials Science and Engineering, Institute of Molecular Engineering and Applied Chemistry, Key Lab of Materials Science and Processing of Anhui Province, Anhui University of Technology, Ma' anshan, Anhui 243002 (China); Chen, Y.W. [Department of Materials Science, Fudan University, Shanghai 200433 (China); Zhang Qianfeng [School of Materials Science and Engineering, Institute of Molecular Engineering and Applied Chemistry, Key Lab of Materials Science and Processing of Anhui Province, Anhui University of Technology, Ma' anshan, Anhui 243002 (China)

    2009-09-15

    Single crystalline ZnO nanorods with wurtzite structure have been prepared by a simple hydrothermal process. The microstructure and composition of the products were studied by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), high-resolution TEM, energy dispersive X-ray spectrum (EDS) and Raman spectrum. The nanorods have diameters ranging from 100 nm to 800 nm and length of longer than 10 {mu}m. Raman peak at 437.8 cm{sup -1} displays the characteristic peak of wurtzite ZnO. Photoluminescence (PL) spectrum shows a blue light emission at 441 nm, which is related to radiative recombination of photo-generated holes with singularly ionized oxygen vacancies.

  3. Single crystalline ZnO nanorods grown by a simple hydrothermal process

    International Nuclear Information System (INIS)

    Pei, L.Z.; Zhao, H.S.; Tan, W.; Yu, H.Y.; Chen, Y.W.; Zhang Qianfeng

    2009-01-01

    Single crystalline ZnO nanorods with wurtzite structure have been prepared by a simple hydrothermal process. The microstructure and composition of the products were studied by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), high-resolution TEM, energy dispersive X-ray spectrum (EDS) and Raman spectrum. The nanorods have diameters ranging from 100 nm to 800 nm and length of longer than 10 μm. Raman peak at 437.8 cm -1 displays the characteristic peak of wurtzite ZnO. Photoluminescence (PL) spectrum shows a blue light emission at 441 nm, which is related to radiative recombination of photo-generated holes with singularly ionized oxygen vacancies.

  4. A simple analytical model of single-event upsets in bulk CMOS

    International Nuclear Information System (INIS)

    Sogoyan, Armen V.; Chumakov, Alexander I.; Smolin, Anatoly A.; Ulanova, Anastasia V.; Boruzdina, Anna B.

    2017-01-01

    During the last decade, multiple new methods of single event upset (SEU) rate prediction for aerospace systems have been proposed. Despite different models and approaches being employed in these methods, they all share relatively high usage complexity and require information about a device that is not always available to an end user. This work presents an alternative approach to estimating SEU cross-section as a function of linear energy transfer (LET) that can be further developed into a method of SEU rate prediction. The goal is to propose a simple, yet physics-based, approach with just two parameters that can be used even in situations when only a process node of the device is known. The developed approach is based on geometrical interpretation of SEU cross-section and an analytical solution to the diffusion problem obtained for a simplified IC topology model. A good fit of the model to the experimental data encompassing 7 generations of SRAMs is demonstrated.

  5. Criticality safety validation: Simple geometry, single unit {sup 233}U systems

    Energy Technology Data Exchange (ETDEWEB)

    Putman, V.L.

    1997-06-01

    Typically used LMITCO criticality safety computational methods are evaluated for suitability when applied to INEEL {sup 233}U systems which reasonably can be modeled as simple-geometry, single-unit systems. Sixty-seven critical experiments of uranium highly enriched in {sup 233}U, including 57 aqueous solution, thermal-energy systems and 10 metal, fast-energy systems, were modeled. These experiments include 41 cylindrical and 26 spherical cores, and 41 reflected and 26 unreflected systems. No experiments were found for intermediate-neutron-energy ranges, or with interstitial non-hydrogenous materials typical of waste systems, mixed {sup 233}U and plutonium, or reflectors such as steel, lead, or concrete. No simple geometry experiments were found with cubic or annular cores, or approximating infinite sea systems. Calculations were performed with various tools and methodologies. Nine cross-section libraries, based on ENDF/B-IV, -V, or -VI.2, or on Hansen-Roach source data, were used with cross-section processing methods of MCNP or SCALE. The k{sub eff} calculations were performed with neutral-particle transport and Monte Carlo methods of criticality codes DANT, MCNP 4A, and KENO Va.

  6. Simple single-emitting layer hybrid white organic light emitting with high color stability

    Science.gov (United States)

    Nguyen, C.; Lu, Z. H.

    2017-10-01

    Simultaneously achieving a high efficiency and color quality at luminance levels required for solid-state lighting has been difficult for white organic light emitting diodes (OLEDs). Single-emitting layer (SEL) white OLEDs, in particular, exhibit a significant tradeoff between efficiency and color stability. Furthermore, despite the simplicity of SEL white OLEDs being its main advantage, the reported device structures are often complicated by the use of multiple blocking layers. In this paper, we report a highly simplified three-layered white OLED that achieves a low turn-on voltage of 2.7 V, an external quantum efficiency of 18.9% and power efficiency of 30 lm/W at 1000 cd/cm2. This simple white OLED also shows good color quality with a color rendering index of 75, CIE coordinates (0.42, 0.46), and little color shifting at high luminance. The device consists of a SEL sandwiched between a hole transport layer and an electron transport layer. The SEL comprises a thermally activated delayer fluorescent molecule having dual functions as a blue emitter and as a host for other lower energy emitters. The improved color stability and efficiency in such a simple device structure is explained as due to the elimination of significant energy barriers at various organic-organic interfaces in the traditional devices having multiple blocking layers.

  7. A large collapsed-state RNA can exhibit simple exponential single-molecule dynamics.

    Science.gov (United States)

    Smith, Glenna J; Lee, Kang Taek; Qu, Xiaohui; Xie, Zheng; Pesic, Jelena; Sosnick, Tobin R; Pan, Tao; Scherer, Norbert F

    2008-05-09

    The process of large RNA folding is believed to proceed from many collapsed structures to a unique functional structure requiring precise organization of nucleotides. The diversity of possible structures and stabilities of large RNAs could result in non-exponential folding kinetics (e.g. stretched exponential) under conditions where the molecules have not achieved their native state. We describe a single-molecule fluorescence resonance energy transfer (FRET) study of the collapsed-state region of the free energy landscape of the catalytic domain of RNase P RNA from Bacillus stearothermophilus (C(thermo)). Ensemble measurements have shown that this 260 residue RNA folds cooperatively to its native state at >or=1 mM Mg(2+), but little is known about the conformational dynamics at lower ionic strength. Our measurements of equilibrium conformational fluctuations reveal simple exponential kinetics that reflect a small number of discrete states instead of the expected inhomogeneous dynamics. The distribution of discrete dwell times, collected from an "ensemble" of 300 single molecules at each of a series of Mg(2+) concentrations, fit well to a double exponential, which indicates that the RNA conformational changes can be described as a four-state system. This finding is somewhat unexpected under [Mg(2+)] conditions in which this RNA does not achieve its native state. Observation of discrete well-defined conformations in this large RNA that are stable on the seconds timescale at low [Mg(2+)] (<0.1 mM) suggests that even at low ionic strength, with a tremendous number of possible (weak) interactions, a few critical interactions may produce deep energy wells that allow for rapid averaging of motions within each well, and yield kinetics that are relatively simple.

  8. A simple formula for estimating global solar radiation in central arid deserts of Iran

    International Nuclear Information System (INIS)

    Sabziparvar, Ali A.

    2008-01-01

    Over the last two decades, using simple radiation models has been an interesting task to estimate daily solar radiation in arid and semi-arid deserts such as those in Iran, where the number of solar observation sites is poor. In Iran, most of the models used so far, have been validated for a few specific locations based on short-term solar observations. In this work, three different radiation models (Sabbagh, Paltridge, Daneshyar) have been revised to predict the climatology of monthly average daily solar radiation on horizontal surfaces in various cities in central arid deserts of Iran. The modifications are made by the inclusion of altitude, monthly total number of dusty days and seasonal variation of Sun-Earth distance. A new height-dependent formula is proposed based on MBE, MABE, MPE and RMSE statistical analysis. It is shown that the revised Sabbagh method can be a good estimator for the prediction of global solar radiation in arid and semi-arid deserts with an average error of less than 2%, that performs a more accurate prediction than those in the previous studies. The required data for the suggested method are usually available in most meteorological sites. For the locations, where some of the input data are not reported, an alternative approach is presented. (author)

  9. Protein Data Bank (PDB): The Single Global Macromolecular Structure Archive.

    Science.gov (United States)

    Burley, Stephen K; Berman, Helen M; Kleywegt, Gerard J; Markley, John L; Nakamura, Haruki; Velankar, Sameer

    2017-01-01

    The Protein Data Bank (PDB)--the single global repository of experimentally determined 3D structures of biological macromolecules and their complexes--was established in 1971, becoming the first open-access digital resource in the biological sciences. The PDB archive currently houses ~130,000 entries (May 2017). It is managed by the Worldwide Protein Data Bank organization (wwPDB; wwpdb.org), which includes the RCSB Protein Data Bank (RCSB PDB; rcsb.org), the Protein Data Bank Japan (PDBj; pdbj.org), the Protein Data Bank in Europe (PDBe; pdbe.org), and BioMagResBank (BMRB; www.bmrb.wisc.edu). The four wwPDB partners operate a unified global software system that enforces community-agreed data standards and supports data Deposition, Biocuration, and Validation of ~11,000 new PDB entries annually (deposit.wwpdb.org). The RCSB PDB currently acts as the archive keeper, ensuring disaster recovery of PDB data and coordinating weekly updates. wwPDB partners disseminate the same archival data from multiple FTP sites, while operating complementary websites that provide their own views of PDB data with selected value-added information and links to related data resources. At present, the PDB archives experimental data, associated metadata, and 3D-atomic level structural models derived from three well-established methods: crystallography, nuclear magnetic resonance spectroscopy (NMR), and electron microscopy (3DEM). wwPDB partners are working closely with experts in related experimental areas (small-angle scattering, chemical cross-linking/mass spectrometry, Forster energy resonance transfer or FRET, etc.) to establish a federation of data resources that will support sustainable archiving and validation of 3D structural models and experimental data derived from integrative or hybrid methods.

  10. New simple deposition model based on reassessment of global fallout data 1954 - 1976

    Energy Technology Data Exchange (ETDEWEB)

    Palsson, S.E. [Icelandic Radiation Safety Authority, Reykjavik (Iceland); Bergan, T.D. [Directorate for Civil Protection and Emergency Planning, Toensberg (Norway); Howard, B.J. [Centre for Ecology and Hydrology, Lancaster Environment Centre, Lancaster (United Kingdom); Ikaeheimonen, T.K. [STUK - Radiation and Nuclear Safety Authority, Helsinki (Finland); Isaksson, M. [Univ. of Gothenburg. Dept. of Radiation Physics, Institute of Clinical Sciences, Sahlgren Academy, Gothenburg (Sweden); Nielsen, Sven P. [Technical Univ. of Denmark. DTU Nutech, Roskilde (Denmark); Paatero, J. [Finnish Meteorological Institute. Observation Services, Helsinki (Finland)

    2012-12-15

    Atmospheric testing of nuclear weapons began in 1945 and largely ceased in 1963. This testing is the major cause of distribution of man-made radionuclides over the globe and constitutes a background that needs to be considered when effects of other sources are estimated. The main radionuclides of long term (after the first months) concern are generally assumed to be {sup 137}Cs and {sup 90}Sr. It has been known for a long time that the deposition density of {sup 137}Cs and {sup 90}Sr is approximately proportional to the amount of precipitation. But the use of this proportional relationship raised some questions such as (a) over how large area can it be assumed that the concentration in precipitation is the same at any given time; (b) how does this agree with the observed latitude dependency of deposition density and (c) are the any other parameters that could be of use in a simple model describing global fallout? These issues were amongst those taken up in the NKS-B EcoDoses activity. The preliminary results for {sup 137}Cs and {sup 90}Sr showed for each that the measured concentration had been similar at many European and N-American sites at any given time and that the change with time had been similar. These finding were followed up in a more thorough study in this (DepEstimates) activity. Global data (including the US EML and UK AERE data sets) from 1954 - 1976 for {sup 90}Sr and {sup 137}Cs were analysed testing how well different potential explanatory variables could describe the deposition density. The best fit was obtained by not assuming the traditional proportional relationship, but instead a non-linear power function. The predictions obtained using this new model may not be significantly different from those obtained using the traditional model, when using a limited data set such as from one country as a test in this report showed. But for larger data sets and understanding of underlying processes the new model should be an improvement. (Author)

  11. A learning rule for very simple universal approximators consisting of a single layer of perceptrons.

    Science.gov (United States)

    Auer, Peter; Burgsteiner, Harald; Maass, Wolfgang

    2008-06-01

    One may argue that the simplest type of neural networks beyond a single perceptron is an array of several perceptrons in parallel. In spite of their simplicity, such circuits can compute any Boolean function if one views the majority of the binary perceptron outputs as the binary output of the parallel perceptron, and they are universal approximators for arbitrary continuous functions with values in [0,1] if one views the fraction of perceptrons that output 1 as the analog output of the parallel perceptron. Note that in contrast to the familiar model of a "multi-layer perceptron" the parallel perceptron that we consider here has just binary values as outputs of gates on the hidden layer. For a long time one has thought that there exists no competitive learning algorithm for these extremely simple neural networks, which also came to be known as committee machines. It is commonly assumed that one has to replace the hard threshold gates on the hidden layer by sigmoidal gates (or RBF-gates) and that one has to tune the weights on at least two successive layers in order to achieve satisfactory learning results for any class of neural networks that yield universal approximators. We show that this assumption is not true, by exhibiting a simple learning algorithm for parallel perceptrons - the parallel delta rule (p-delta rule). In contrast to backprop for multi-layer perceptrons, the p-delta rule only has to tune a single layer of weights, and it does not require the computation and communication of analog values with high precision. Reduced communication also distinguishes our new learning rule from other learning rules for parallel perceptrons such as MADALINE. Obviously these features make the p-delta rule attractive as a biologically more realistic alternative to backprop in biological neural circuits, but also for implementations in special purpose hardware. We show that the p-delta rule also implements gradient descent-with regard to a suitable error measure

  12. A simple method for microtuber production in dioscorea opposita using single nodal segments

    International Nuclear Information System (INIS)

    Li, M.; Wang, Y; Liu, W.; Li, S.

    2015-01-01

    Dioscorea opposita Thunb. (Chinese yam) is an important tuber crop in East Asia because of its dual benefits edible and medicinal properties. Microtubers may provide a feasible alternative to in-vitro-grown plantlets as a means of micropropagation and a way to exchange healthy planting material. In this study, we have developed a simplified culture method for In vitro production of microtubers from D. opposita cv. Tiegun. In this method, microtubers formed in 98% of the internodes of single nodal segments after four weeks of dark-incubation when cultured in MS medium supplemented with 60 g sucrose 1-1 with shaking. Anatomical observations strongly supported the process of tuberization. We also found that 66% of the microtubers produced In vitro sprouted two months after transfer to vermiculite. The protocol presented here provides a simple model for studying the physiological, biochemical, and molecular mechanisms of tuberization in D. opposita, and shows good potential for large-scale production of microtubers as well. (author)

  13. A Simple Interface for 3D Position Estimation of a Mobile Robot with Single Camera.

    Science.gov (United States)

    Chao, Chun-Tang; Chung, Ming-Hsuan; Chiou, Juing-Shian; Wang, Chi-Jo

    2016-03-25

    In recent years, there has been an increase in the number of mobile robots controlled by a smart phone or tablet. This paper proposes a visual control interface for a mobile robot with a single camera to easily control the robot actions and estimate the 3D position of a target. In this proposal, the mobile robot employed an Arduino Yun as the core processor and was remote-controlled by a tablet with an Android operating system. In addition, the robot was fitted with a three-axis robotic arm for grasping. Both the real-time control signal and video transmission are transmitted via Wi-Fi. We show that with a properly calibrated camera and the proposed prototype procedures, the users can click on a desired position or object on the touchscreen and estimate its 3D coordinates in the real world by simple analytic geometry instead of a complicated algorithm. The results of the measurement verification demonstrates that this approach has great potential for mobile robots.

  14. Single-Grasp Object Classification and Feature Extraction with Simple Robot Hands and Tactile Sensors.

    Science.gov (United States)

    Spiers, Adam J; Liarokapis, Minas V; Calli, Berk; Dollar, Aaron M

    2016-01-01

    Classical robotic approaches to tactile object identification often involve rigid mechanical grippers, dense sensor arrays, and exploratory procedures (EPs). Though EPs are a natural method for humans to acquire object information, evidence also exists for meaningful tactile property inference from brief, non-exploratory motions (a 'haptic glance'). In this work, we implement tactile object identification and feature extraction techniques on data acquired during a single, unplanned grasp with a simple, underactuated robot hand equipped with inexpensive barometric pressure sensors. Our methodology utilizes two cooperating schemes based on an advanced machine learning technique (random forests) and parametric methods that estimate object properties. The available data is limited to actuator positions (one per two link finger) and force sensors values (eight per finger). The schemes are able to work both independently and collaboratively, depending on the task scenario. When collaborating, the results of each method contribute to the other, improving the overall result in a synergistic fashion. Unlike prior work, the proposed approach does not require object exploration, re-grasping, grasp-release, or force modulation and works for arbitrary object start positions and orientations. Due to these factors, the technique may be integrated into practical robotic grasping scenarios without adding time or manipulation overheads.

  15. Decision Support System to Choose Digital Single Lens Camera with Simple Additive Weighting Method

    Directory of Open Access Journals (Sweden)

    Tri Pina Putri

    2016-11-01

    Full Text Available One of the technologies that evolve today is Digital Single Lens Reflex (DSLR camera. The number of products makes users have difficulties to choose the appropriate camera based on their criteria. Users may utilize several ways to help them choosing the intended camera such as using magazine, internet, and other media. This paper discusses about a web based decision support system to choose cameras by using SAW (Simple Additive Weighting method in order to make the decision process more effective and efficient. This system is expected to give recommendations about the camera which is appropriate with the user’s need and criteria based on the cost, the resolution, the feature, the ISO, and the censor. The system was implemented by using PHP and MySQL. Based on the result of questionnaire distributed to 20 respondents, 60% respondents agree that this decision support system can help users to choose the appropriate camera DSLR in accordance with the user’s need, 60% of respondents agree that this decision support system is more effective to choose DSLR camera and 75% of respondents agree that this system is more efficient. In addition, 60.55% of respondents agree that this system has met 5 Es Usability Framework.

  16. A Simple Interface for 3D Position Estimation of a Mobile Robot with Single Camera

    Directory of Open Access Journals (Sweden)

    Chun-Tang Chao

    2016-03-01

    Full Text Available In recent years, there has been an increase in the number of mobile robots controlled by a smart phone or tablet. This paper proposes a visual control interface for a mobile robot with a single camera to easily control the robot actions and estimate the 3D position of a target. In this proposal, the mobile robot employed an Arduino Yun as the core processor and was remote-controlled by a tablet with an Android operating system. In addition, the robot was fitted with a three-axis robotic arm for grasping. Both the real-time control signal and video transmission are transmitted via Wi-Fi. We show that with a properly calibrated camera and the proposed prototype procedures, the users can click on a desired position or object on the touchscreen and estimate its 3D coordinates in the real world by simple analytic geometry instead of a complicated algorithm. The results of the measurement verification demonstrates that this approach has great potential for mobile robots.

  17. Determination of particle-release conditions in microfiltration: A simple single-particle model tested on a model membrane

    NARCIS (Netherlands)

    Kuiper, S.; van Rijn, C.J.M.; Nijdam, W.; Krijnen, Gijsbertus J.M.; Elwenspoek, Michael Curt

    2000-01-01

    A simple single-particle model was developed for cross-flow microfiltration with microsieves. The model describes the cross-flow conditions required to release a trapped spherical particle from a circular pore. All equations are derived in a fully analytical way without any fitting parameters. For

  18. A simple model for variations in global mean temperature: implications for decadal variability, the global warming hiatus, and recent temperature rise

    Science.gov (United States)

    Hu, S.; Fedorov, A. V.

    2017-12-01

    Global mean surface temperature (GMST) has steadily risen since the mid-19th century, and at the same time experienced significant variations on interannual and decadal timescales. Various mechanisms have been proposed to explain such variations, ranging from the Pacific decadal oscillation to volcanic eruptions. In this study, we construct a simple, physically-based model of GMST variations that incorporates greenhouse gas emissions, ENSO forcing, and stratospheric sulfate aerosols. The model closely reproduces the history of GMST changes since 1880 with the mean squared error about 0.05°C for the past 60 years, smaller than the typical error of GMST observations (see the figure attached). It also accurately captures decadal GMST variations, including the global warming hiatus in the early 21stcentury. This model can be used to understand the causes of the observed GMST variations and requires little computational resource. Our results confirm that weak El Niño activity was the major cause of the recent global warming hiatus, while the rapid temperature rise since 2014 is due to atmospheric heat release during 2014-2016 El Niño conditions in addition to the continuing background global warming trend. The model can be also used to make predictions for next-year GMST in the short term, and future climate projections in the long term. We will also discuss the implications of this simple model for paleoclimate reconstructions and GCM performance evaluations.

  19. Simple non-Markovian microscopic models for the depolarizing channel of a single qubit

    International Nuclear Information System (INIS)

    Fonseca Romero, K M; Lo Franco, R

    2012-01-01

    The archetypal one-qubit noisy channels - depolarizing, phase-damping and amplitude-damping channels - describe both Markovian and non-Markovian evolution. Simple microscopic models for the depolarizing channel, both classical and quantum, are considered. Microscopic models that describe phase-damping and amplitude-damping channels are briefly reviewed.

  20. Single-session percutaneous ethanol sclerotherapy in simple renal cysts in children: long-term follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Akinci, Devrim; Gumus, Burcak; Ozkan, Orhan S.; Ozmen, Mustafa N.; Akhan, Okan [Hacettepe University School of Medicine, Department of Radiology, Ankara (Turkey)

    2005-02-01

    Simple renal cysts are rare in children and managed conservatively unless symptomatic. To demonstrate the efficacy and long-term results of single-session ethanol sclerotherapy in symptomatic simple renal cysts in children. Three simple renal cysts in three children (age 1, 5 and 16 years) were included in the study. Indications for treatment were flank pain (n=1), hypertension (n=1), and increasing cyst size and urinary tract infection (n=1). The mean follow-up period was 5.5 years (range 3-7 years). The procedures were performed with the guidance of US and fluoroscopy and under IV sedation. After the cystogram, 95% ethanol with a volume of 40% of the cyst volume (but not more than 100 ml) was used as the sclerosing agent. Two cysts disappeared completely, while the volume reduction was 99% for the third cyst at the end of the first year. CT demonstrated calcification of the cyst without an enhancing soft-tissue component in the third one 7 years after sclerotherapy. After the procedures, hypertension and pain resolved without any medication. There were no complications during the procedures or during follow-up. Cytological examination was unremarkable in all patients. Percutaneous treatment of symptomatic simple renal cysts in children with single-session ethanol sclerotherapy is a safe, effective and minimally invasive procedure. Calcification owing to sclerotherapy can be observed on follow-up. (orig.)

  1. Validation of a simple isotopic technique for the measurement of global and separated renal function

    International Nuclear Information System (INIS)

    Chachati, A.; Meyers, A.; Rigo, P.; Godon, J.P.

    1986-01-01

    Schlegel and Gates described an isotopic method for the measurement of global and separated glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) based on the determination by scintillation camera of the fraction of the injected dose (99mTc-DTPA-[ 131 I]hippuran) present in the kidneys 1-3 min after its administration. This method requires counting of the injected dose and attenuation correction, but no blood or urine sampling. We validated this technique by the simultaneous infusion of inulin and para-amino hippuric acid (PAH) in patients with various levels of renal function (anuric to normal). To better define individual renal function we studied 9 kidneys in patients either nephrectomized or with a nephrostomy enabling separated function measurement. A good correlation between inulin, PAH clearance, and isotopic GFR-ERPF measurement for both global and separate renal function was observed

  2. A simple climatology of westerly jet streams in global reanalysis datasets part 1: mid-latitude upper tropospheric jets

    Science.gov (United States)

    Rikus, Lawrie

    2018-04-01

    A simple closed contour object identification scheme has been applied to the zonal mean monthly mean zonal wind fields from nine global reanalysis data sets for 31 years of the satellite era (1979-2009) to identify objects corresponding to westerly jet streams. The results cluster naturally into six individual jet streams but only the mid-latitude upper-tropospheric jets are considered here. The time series of the jet properties from all reanalyses are decomposed into seasonal means and anomalies, and correlations between variables are evaluated, with the aim of identifying robust features which can form the basis of evaluation metrics for climate model simulations of the twentieth century. There is substantial agreement between all the reanalyses for all jet properties although there are some systematic differences with particular data sets. Some of the results from the object identification applied to the reanalyses are used in a simple example of a model evaluation score for the zonal mean jet seasonal cycle.

  3. Harmonic analysis and global solvability of a differential operator invariant on motion groups and semi-simple Lie groups

    International Nuclear Information System (INIS)

    El-Hussein, K.

    1991-08-01

    Let V be a real finite dimensional vector space and let K be a connected compact Lie group, which acts on V by means of a continuous linear representation ρ. Let G=V x p K be the motion group which is the semi-direct product of V by K and let P be an invariant differential operator on G. In this paper we give a necessary and sufficient condition for the global solvability of P on G. Now let G be a connected semi-simple Lie group with finite centre and let P be an invariant differential operator on G. We give also a necessary and sufficient condition for the global solvability of P on G. (author). 8 refs

  4. A Single Global Small-User Nuclear Repository

    International Nuclear Information System (INIS)

    Conca, J.L.; Wright, J.

    2009-01-01

    Global energy partnerships in nuclear power, proposed by France, Russia, U.S. and England, seek to address the proliferation issue by controlling fuel production and nuclear materials, removing the need for each country to develop enrichment, fabrication, recycling or disposal capabilities. Several of the large generator countries such as France, the U.S., Japan, S. Korea, Russia, the U.K., China and India, all have plans for deep geologic repositories because they anticipate sufficient waste over the next century to justify the expense of a repository. However, countries having, or planning, less than five reactors, such as Egypt, Iran, Indonesia, Brazil and about 30 other countries, will not have sufficient waste generation, or a favorable geologic site, to justify the economic and environmental issues of developing their own repository. The Salado salt formation in New Mexico, set aside for nuclear waste disposal within the 16 square-mile area by the Land Withdrawal Act of 1992, is the most optimal geologic formation for the permanent disposal of any nuclear waste and is easily able to host all of the commercial nuclear waste that will be generated in the next thousand years. The U.S. commercial nuclear waste needs presently surpass all others, and will for the foreseeable future. Hosting the relatively small amount of waste from these small-user nations will add little to U.S. waste stream while the cost/benefit analysis from the standpoint of operations, safety, geology, cost and proliferation is overwhelmingly positive for developing such a global repository. Oceanic and overland transportation, high-level disposal logistics and costs from several programs, including WIPP, have demonstrated that the operation would pay for itself from international user fees with no U.S. taxpayer dollars required and still save the world about $400 billion over 100 years. The ethical considerations alone are compelling. (authors)

  5. Laparoscopic treatment of symptomatic simple renal cysts in children: single-center experience

    Directory of Open Access Journals (Sweden)

    Antonio Marte

    2018-05-01

    Full Text Available Simple renal cysts, although common in adults, are rare in children. They are usually discovered incidentally in the course of the study of other urinary tract symptoms, although they are not always asymptomatic. Renal cysts can be classified as being either simple or complex. The purpose of this review is to present our case series of simple symptomatic renal cysts treated with laparoscopy. Nineteen patients with symptomatic renal cysts (6 to 13.5 cm were referred to our institution between January 2006 and January 2017. They comprised 12 (40.5% females and seven (59.5% males, aged 8 to 15, with a mean age of 12.2 years. Of these patients, nine had previously been treated unsuccessfully by ultrasound-guided aspiration/alcoholization with 95%-ethanol, between 9 and 13 months prior to the laparoscopy. Five patients had undergone one treatment and four had undergone two treatments. All of the patients were treated by laparoscopic threetrocar deroofing. The cysts were opened and the wall excised using scissors and a monopolar hook. In most cases, to better handle the edges of the cyst and obtain a better grip, a needle was used to aspirate a small amount of fluid (used for cytological examination. The wall of the cyst was excised, the cyst edges were sealed, and the perirenal fat was placed on the bottom of the cyst (wadding technique. The mean operating time was 95 minutes (range 50- 150. The postoperative course was uneventful for all of the patients. The hospital stay ranged from one to three days. All of the patients were asymptomatic following the treatment. At a mean follow-up time of 3.6 years, none of the patients had experienced a recurrence. Renal function, as assessed by a MAG3 renal scintigraphy scan, was well-preserved in all of the patients, and all of them undergo an annual ultrasound scan.

  6. A simple angular transmit diversity scheme using a single RF frontend for PSK modulation schemes

    DEFF Research Database (Denmark)

    Alrabadi, Osama Nafeth Saleem; Papadias, Constantinos B.; Kalis, Antonis

    2009-01-01

    array (SPA) with a single transceiver, and an array area of 0.0625 square wavelengths. The scheme which requires no channel state information (CSI) at the transmitter, provides mainly a diversity gain to combat against multipath fading. The performance/capacity of the proposed diversity scheme...

  7. Sintered pellets: A simple and cost effective method to predict the performance of GGAG:Ce single crystals

    International Nuclear Information System (INIS)

    Meng, Fang; Koschan, Merry; Melcher, Charles L.; Cohen, Peter

    2015-01-01

    Highlights: • Sintered pellets were firstly used to predict the performance of single crystals. • Similar properties between sintered pellets and single crystals were investigated. • B and Ba increase luminescence intensity in pellets and light yield in crystals. • Ca shortens photoluminescence decay in pellets and scintillation decay in crystals. - Abstract: Polycrystalline Gd 3 Ga 3 Al 2 O 12 :Ce (GGAG:Ce) pellets with various codopants were prepared via solid-state synthesis and characterized by X-ray diffraction, radioluminescence (RL), photoluminescence (PL), reflectivity and PL decay measurements. GGAG:Ce pellets codoped with B and Ba were found to have higher RL intensity than pellets with other codopants, while Ca codoping improved the decay time but reduced the RL intensity. These results were strongly correlated with the performance of these codopants in GGAG:Ce single crystals. The light yield of the single crystals codoped with B or Ba was ∼15% higher than the light yield of the GGAG:Ce crystal without codoping, while Ca codoping in single crystals resulted in lower light yield but shorter scintillation decay time (43 ns vs. 56 ns). The consistent performance of these codopants in both matrix forms indicates that sintering pellets may be used as a simple cost effective technique to evaluate compositions for likely single crystal scintillator performance

  8. Simple Atomic Quantum Memory Suitable for Semiconductor Quantum Dot Single Photons

    Science.gov (United States)

    Wolters, Janik; Buser, Gianni; Horsley, Andrew; Béguin, Lucas; Jöckel, Andreas; Jahn, Jan-Philipp; Warburton, Richard J.; Treutlein, Philipp

    2017-08-01

    Quantum memories matched to single photon sources will form an important cornerstone of future quantum network technology. We demonstrate such a memory in warm Rb vapor with on-demand storage and retrieval, based on electromagnetically induced transparency. With an acceptance bandwidth of δ f =0.66 GHz , the memory is suitable for single photons emitted by semiconductor quantum dots. In this regime, vapor cell memories offer an excellent compromise between storage efficiency, storage time, noise level, and experimental complexity, and atomic collisions have negligible influence on the optical coherences. Operation of the memory is demonstrated using attenuated laser pulses on the single photon level. For a 50 ns storage time, we measure ηe2 e 50 ns=3.4 (3 )% end-to-end efficiency of the fiber-coupled memory, with a total intrinsic efficiency ηint=17 (3 )%. Straightforward technological improvements can boost the end-to-end-efficiency to ηe 2 e≈35 %; beyond that, increasing the optical depth and exploiting the Zeeman substructure of the atoms will allow such a memory to approach near unity efficiency. In the present memory, the unconditional read-out noise level of 9 ×10-3 photons is dominated by atomic fluorescence, and for input pulses containing on average μ1=0.27 (4 ) photons, the signal to noise level would be unity.

  9. A GLOBAL REGISTRATION ALGORITHM OF THE SINGLE-CLOSED RING MULTI-STATIONS POINT CLOUD

    Directory of Open Access Journals (Sweden)

    R. Yang

    2018-04-01

    Full Text Available Aimed at the global registration problem of the single-closed ring multi-stations point cloud, a formula in order to calculate the error of rotation matrix was constructed according to the definition of error. The global registration algorithm of multi-station point cloud was derived to minimize the error of rotation matrix. And fast-computing formulas of transformation matrix with whose implementation steps and simulation experiment scheme was given. Compared three different processing schemes of multi-station point cloud, the experimental results showed that the effectiveness of the new global registration method was verified, and it could effectively complete the global registration of point cloud.

  10. Squidpops: A Simple Tool to Crowdsource a Global Map of Marine Predation Intensity.

    Directory of Open Access Journals (Sweden)

    J Emmett Duffy

    Full Text Available We present a simple, standardized assay, the squidpop, for measuring the relative feeding intensity of generalist predators in aquatic systems. The assay consists of a 1.3-cm diameter disk of dried squid mantle tethered to a rod, which is either inserted in the sediment in soft-bottom habitats or secured to existing structure. Each replicate squidpop is scored as present or absent after 1 and 24 hours, and the data for analysis are proportions of replicate units consumed at each time. Tests in several habitats of the temperate southeastern USA (Virginia and North Carolina and tropical Central America (Belize confirmed the assay's utility for measuring variation in predation intensity among habitats, among seasons, and along environmental gradients. In Belize, predation intensity varied strongly among habitats, with reef > seagrass = mangrove > unvegetated bare sand. Quantitative visual surveys confirmed that assayed feeding intensity increased with abundance and species richness of fishes across sites, with fish abundance and richness explaining up to 45% and 70% of the variation in bait loss respectively. In the southeastern USA, predation intensity varied seasonally, being highest during summer and declining in late autumn. Deployments in marsh habitats generally revealed a decline in mean predation intensity from fully marine to tidal freshwater sites. The simplicity, economy, and standardization of the squidpop assay should facilitate engagement of scientists and citizens alike, with the goal of constructing high-resolution maps of how top-down control varies through space and time in aquatic ecosystems, and addressing a broad array of long-standing hypotheses in macro- and community ecology.

  11. Lessons learned in the conduct of a global, large simple trial of treatments indicated for schizophrenia.

    Science.gov (United States)

    Kolitsopoulos, Francesca M; Strom, Brian L; Faich, Gerald; Eng, Sybil M; Kane, John M; Reynolds, Robert F

    2013-03-01

    Large, "practical" or streamlined trials (LSTs) are used to study the effectiveness and/or safety of medicines in real world settings with minimal study imposed interventions. While LSTs have benefits over traditional randomized clinical trials and observational studies, there are inherent challenges to their conduct. Enrollment and follow-up of a large study sample of patients with mental illness pose a particular difficulty. To assist in overcoming operational barriers in future LSTs in psychiatry, this paper describes the recruitment and observational follow-up strategies used for the ZODIAC study, an international, open-label LST, which followed 18,239 persons randomly assigned to one of two treatments indicated for schizophrenia for 1 year. ZODIAC enrolled patients in 18 countries in North America, South America, Europe, and Asia using broad study entry criteria and required minimal clinical care intervention. Recruitment of adequate numbers and continued engagement of both study centers and subjects were significant challenges. Strategies implemented to mitigate these in ZODIAC include global study expansion, study branding, field coordinator and site relations programs, monthly site newsletters, collection of alternate contact information, conduct of national death index (NDI) searches, and frequent sponsor, contract research organization (CRO) and site interaction to share best practices and address recruitment challenges quickly. We conclude that conduct of large LSTs in psychiatric patient populations is feasible, but importantly, realistic site recruitment goals and maintaining site engagement are key factors that need to be considered in early study planning and conduct. Copyright © 2012 Elsevier Inc. All rights reserved.

  12. Microstructure evolution of pure copper during a single pass of simple shear extrusion (SSE): role of shear reversal

    Energy Technology Data Exchange (ETDEWEB)

    Bagherpour, E., E-mail: e.bagherpour@semnan.ac.ir [Faculty of Metallurgical and Materials Engineering, Semnan University, Semnan (Iran, Islamic Republic of); Department of Mechanical Engineering, Doshisha University, Kyotanabe, Kyoto 610–0394 (Japan); Qods, F., E-mail: qods@semnan.ac.ir [Faculty of Metallurgical and Materials Engineering, Semnan University, Semnan (Iran, Islamic Republic of); Ebrahimi, R., E-mail: ebrahimy@shirazu.ac.ir [Department of Materials Science and Engineering, School of Engineering, Shiraz University, Shiraz (Iran, Islamic Republic of); Miyamoto, H., E-mail: hmiyamot@mail.doshisha.ac.jp [Department of Mechanical Engineering, Doshisha University, Kyotanabe, Kyoto 610–0394 (Japan)

    2016-06-01

    In the present paper the role of shear reversal on microstructure, texture and mechanical properties of pure copper during a single pass of the simple shear extrusion (SSE) process was investigated. For SSE processing an appropriate die with a linear die profile was designed and constructed, which imposes forward shear in the first half and reverse shear in the second half channels. Electron back-scattering diffraction (EBSD), transmission electron microscopy (TEM) and scanning transmission electron microscopy (STEM) were used to evaluate the microstructure of the deformed samples. The geometrical nature of this process imposes a distribution of strain results in the inhomogeneous microstructure and the hardness throughout the plane perpendicular to the extrusion direction. Strain reversal during the process results in a slight reduction in dislocation density, the hardness and mean disorientation angle of the samples, and an increase in the grain size. After a complete pass of SSE, dislocation density decreased by ~14% if compared to the middle of the process. This suggests that the dislocation annihilation occurred by the reversal of the shear strain. The simple shear textures were formed gradually and the strongest simple shear textures were observed on the middle of the SSE channel. The degree of the simple shear textures decreases with the distance from the middle plane where the shear is reversed, but the simple shear textures are still the major components after exit of the channel. Hardness variation was modeled by contributions from dislocation strengthening and grain boundary strengthening, where dislocation density is approximated by the misorientation angle of LAGBs which are regarded as dislocation cell boundaries. As a result, the hardness can be predicted successfully by the microstructural features, i.e. the low-angle boundaries, the mean misorientation angle and the fraction of high-angle grain boundaries.

  13. Adjoint eigenfunctions of temporally recurrent single-spiral solutions in a simple model of atrial fibrillation.

    Science.gov (United States)

    Marcotte, Christopher D; Grigoriev, Roman O

    2016-09-01

    This paper introduces a numerical method for computing the spectrum of adjoint (left) eigenfunctions of spiral wave solutions to reaction-diffusion systems in arbitrary geometries. The method is illustrated by computing over a hundred eigenfunctions associated with an unstable time-periodic single-spiral solution of the Karma model on a square domain. We show that all leading adjoint eigenfunctions are exponentially localized in the vicinity of the spiral tip, although the marginal modes (response functions) demonstrate the strongest localization. We also discuss the implications of the localization for the dynamics and control of unstable spiral waves. In particular, the interaction with no-flux boundaries leads to a drift of spiral waves which can be understood with the help of the response functions.

  14. A simple optimization can improve the performance of single feature polymorphism detection by Affymetrix expression arrays

    Directory of Open Access Journals (Sweden)

    Fujisawa Hironori

    2010-05-01

    Full Text Available Abstract Background High-density oligonucleotide arrays are effective tools for genotyping numerous loci simultaneously. In small genome species (genome size: Results We compared the single feature polymorphism (SFP detection performance of whole-genome and transcript hybridizations using the Affymetrix GeneChip® Rice Genome Array, using the rice cultivars with full genome sequence, japonica cultivar Nipponbare and indica cultivar 93-11. Both genomes were surveyed for all probe target sequences. Only completely matched 25-mer single copy probes of the Nipponbare genome were extracted, and SFPs between them and 93-11 sequences were predicted. We investigated optimum conditions for SFP detection in both whole genome and transcript hybridization using differences between perfect match and mismatch probe intensities of non-polymorphic targets, assuming that these differences are representative of those between mismatch and perfect targets. Several statistical methods of SFP detection by whole-genome hybridization were compared under the optimized conditions. Causes of false positives and negatives in SFP detection in both types of hybridization were investigated. Conclusions The optimizations allowed a more than 20% increase in true SFP detection in whole-genome hybridization and a large improvement of SFP detection performance in transcript hybridization. Significance analysis of the microarray for log-transformed raw intensities of PM probes gave the best performance in whole genome hybridization, and 22,936 true SFPs were detected with 23.58% false positives by whole genome hybridization. For transcript hybridization, stable SFP detection was achieved for highly expressed genes, and about 3,500 SFPs were detected at a high sensitivity (> 50% in both shoot and young panicle transcripts. High SFP detection performances of both genome and transcript hybridizations indicated that microarrays of a complex genome (e.g., of Oryza sativa can be

  15. A tunable and switchable single-longitudinal-mode dual-wavelength fiber laser with a simple linear cavity.

    Science.gov (United States)

    He, Xiaoying; Fang, Xia; Liao, Changrui; Wang, D N; Sun, Junqiang

    2009-11-23

    A simple linear cavity erbium-doped fiber laser based on a Fabry-Perot filter which consists of a pair of fiber Bragg gratings is proposed for tunable and switchable single-longitudinal-mode dual-wavelength operation. The single-longitudinal-mode is obtained by the saturable absorption of an unpumed erbium-doped fiber together with a narrow-band fiber Bragg grating. Under the high pump power (>166 mW) condition, the stable dual-wavelength oscillation with uniform amplitude can be realized by carefully adjusting the polarization controller in the cavity. Wavelength selection and switching are achieved by tuning the narrow-band fiber Bragg grating in the system. The spacing of the dual-wavelength can be selected at 0.20 nm (approximately 25.62 GHz), 0.22 nm (approximately 28.19 GHz) and 0.54 nm (approximately 69.19 GHz).

  16. Outcomes of robot-assisted simple enucleation of renal masses: A single European center experience.

    Science.gov (United States)

    Matei, Deliu Victor; Vartolomei, Mihai Dorin; Musi, Gennaro; Renne, Giuseppe; Tringali, Valeria Maria Lucia; Mistretta, Francesco Alessandro; Delor, Maurizio; Russo, Andrea; Cioffi, Antonio; Bianchi, Roberto; Cozzi, Gabriele; Di Trapani, Ettore; Bottero, Danilo; Cordima, Giovanni; Lucarelli, Giuseppe; Ferro, Matteo; de Cobelli, Ottavio

    2017-05-01

    The aim of this study was to assess the ability of pre-and intraoperative parameters, to predict the risk of perioperative complications after robot-assisted laparoscopic simple enucleation (RASE) of renal masses, and to evaluate the rate of trifecta achievement of this approach stratifying the cohort according to the use of ischemia during the enucleation.From April 2009 to June 2016, 129 patients underwent RASE at our Institution. We stratified the procedures in 2 groups: clamping and clamp-less RASE. After RASE, all specimens were retrospectively reviewed to assess the surface-intermediate-base (SIB) scoring system. Patients were followed-up according to the European Association of Urology guidelines recommendations. All pre-, intra-, and postoperative outcomes were prospectively collected in a customized database and retrospectively analyzed.A total of 112 (86.8%) patients underwent a pure RASE and 17 (13.2%) had a hybrid according to SIB classification system. The mean age was 61.17 years. In 21 patients (16.3%), complications occurred, 13 (61.9%) were Clavien 1 and 2, while 8 were Clavien 3a and b complications. Statistical significant association with complications was found in patients with American Society of Anestesiology (ASA) score 3 (44.5%, P = .04), longer mean operative time (OT) 195 versus 161.36 minutes (P =.03), mean postoperative hemoglobin (Hb) 10.1 versus 11.8 (P 3, longer OT, and ΔHb. RASE is suitable for the clamp-less approach, which allows to perform easier the pure enucleation (SIB 0) and to obtain higher rates of trifecta outcomes.

  17. A Simple Negative Interaction in the Positive Transcriptional Feedback of a Single Gene Is Sufficient to Produce Reliable Oscillations

    Science.gov (United States)

    Miró-Bueno, Jesús M.; Rodríguez-Patón, Alfonso

    2011-01-01

    Negative and positive transcriptional feedback loops are present in natural and synthetic genetic oscillators. A single gene with negative transcriptional feedback needs a time delay and sufficiently strong nonlinearity in the transmission of the feedback signal in order to produce biochemical rhythms. A single gene with only positive transcriptional feedback does not produce oscillations. Here, we demonstrate that this single-gene network in conjunction with a simple negative interaction can also easily produce rhythms. We examine a model comprised of two well-differentiated parts. The first is a positive feedback created by a protein that binds to the promoter of its own gene and activates the transcription. The second is a negative interaction in which a repressor molecule prevents this protein from binding to its promoter. A stochastic study shows that the system is robust to noise. A deterministic study identifies that the dynamics of the oscillator are mainly driven by two types of biomolecules: the protein, and the complex formed by the repressor and this protein. The main conclusion of this paper is that a simple and usual negative interaction, such as degradation, sequestration or inhibition, acting on the positive transcriptional feedback of a single gene is a sufficient condition to produce reliable oscillations. One gene is enough and the positive transcriptional feedback signal does not need to activate a second repressor gene. This means that at the genetic level an explicit negative feedback loop is not necessary. The model needs neither cooperative binding reactions nor the formation of protein multimers. Therefore, our findings could help to clarify the design principles of cellular clocks and constitute a new efficient tool for engineering synthetic genetic oscillators. PMID:22205920

  18. A simple framework for assessing the trade-off between the climate impact of aviation carbon dioxide emissions and contrails for a single flight

    International Nuclear Information System (INIS)

    A Irvine, E; J Hoskins, B; P Shine, K

    2014-01-01

    Persistent contrails are an important climate impact of aviation which could potentially be reduced by re-routing aircraft to avoid contrailing; however this generally increases both the flight length and its corresponding CO 2 emissions. Here, we provide a simple framework to assess the trade-off between the climate impact of CO 2 emissions and contrails for a single flight, in terms of the absolute global warming potential and absolute global temperature potential metrics for time horizons of 20, 50 and 100 years. We use the framework to illustrate the maximum extra distance (with no altitude changes) that can be added to a flight and still reduce its overall climate impact. Small aircraft can fly up to four times further to avoid contrailing than large aircraft. The results have a strong dependence on the applied metric and time horizon. Applying a conservative estimate of the uncertainty in the contrail radiative forcing and climate efficacy leads to a factor of 20 difference in the maximum extra distance that could be flown to avoid a contrail. The impact of re-routing on other climatically-important aviation emissions could also be considered in this framework. (letters)

  19. Production of single superphosphate labeled with 34S Produção de superfosfato simples marcado com 34S

    Directory of Open Access Journals (Sweden)

    Alexssandra Luiza Rodrigues Molina Rossete

    2008-02-01

    Full Text Available Single superphosphate is currently one of the mostly used fertilizers as an alternative source for phosphorus and sulphur. Sulphur presents four stable isotopes (32S, 33S, 34S, and 36S with natural abundances of 95.00; 0.76; 4.22; and 0.014% in atoms, respectively. Single superphosphate labeled with the 34S isotope was obtained from a chemical reaction in stoichiometric amounts between Ca(H2PO42 and Ca34SO4.2H2O. Calcium sulphate (Ca34SO4.2H2O was enriched with 5.85 ± 0.01 atoms % of 34S. The Ca(H2PO42 reagent was obtained from a reaction between CaCl2.2H2O and H3PO4. The reaction between the Ca(H2PO42 thus produced and the labeled Ca34SO4.2H2O compound was then performed to obtain the 34S-labeled single surperphosphate. The thermal decomposition of the labeled superphosphate for the production of gaseous 34SO2 was carried out under a vacuum line at 900ºC in the presence of NaPO3. The isotopic determination of S (atoms % of 34S was carried out on an ATLAS-MAT model CH-4 mass spectrometer. The production yield of Ca(H2PO42 and labeled single superphosphate were approximately 97 and 99% respectively, and the purity level of the labeled single superphosphate was estimated as 96%. No isotopic fractionation was observed in the production process of 34S-labeled single superphosphate.O superfosfato simples é um dos fertilizantes mais utilizados atualmente como fonte de fósforo e uma alternativa para enxofre. O enxofre apresenta quatro isótopos estáveis, 32S, 33S, 34S e 36S, com abundância natural de 95,00; 0,76; 4,22 e 0,014% em átomos, respectivamente. O superfosfato simples marcado com 34S foi obtido a partir da reação química em proporção estequiométrica entre o Ca(H2PO42 e o Ca34SO4.2H2O. O Ca34SO4.2H2O foi enriquecido com 5,85 ± 0,01% em átomos de 34S. O Ca(H2PO42 foi obtido a partir da reação entre CaCl2.2H2O com o H3PO4. A decomposição térmica do superfosfato marcado para produção do 34SO2 gasoso foi realizada em linha de

  20. A road map for the realization of global-scale thorium breeding fuel cycle by single molten-fluoride flow

    International Nuclear Information System (INIS)

    Furukawa, K.; Arakawa, K.; Erbay, L. B.

    2007-01-01

    For global survival in this century, we urgently need to launch a completely new global nuclear fission industry. To get worldwide public acceptance of nuclear energy, improvements are essential not only on safety, radio-waste management and economy but also especially nuclear proliferation resistance and safeguards. However, such global fission industry cannot replace the present fossil fuel industry in the next 50 years, unless the doubling-time of nuclear energy is less than 10 years, preferably 5-7 years. Such a doubling-time cannot be established by any kind of classical 'Fission Breeding Power Station' concept. We need a symbiotic system which couples fission power reactors with a system which can convert fertile thorium to fissile U-233, such as a spallation or D/T fusion (if and when it becomes available). For such a purpose, THORIMS-NES [Thorium Molten-Salt Nuclear Energy Synergetic System] has been proposed, which is composed of simple thermal fission power stations (FUJI) and fissile producing Accelerator Molten-Salt Breeder (AMSB). Its system functions are very ambitious, delicate and complex, but can be realized in the form of simple hardware applying the multifunctional 'single-phase molten-fluoride' circulation system. This system has no difficulties relating with 'radiation-damage', 'heat-removal' and 'chemical processing' owing to the simple 'idealistic ionic liquid' character. FUJI is size-flexible (economical even in smaller sizes), fuel self-sustaining without any continuous chemical processing and without core-graphite replacement, and AMSB is based on a single-fluid molten-salt target/blanket concept, which solves most engineering difficulties such as radiation-damage, heat-removal etc., except high-current proton accelerator development. Several AMSBs are accommodated in the regional centers (several ten sites in the world) with batch chemical processing plants including radio-waste management. The integrated thorium breeding fuel cycle is

  1. A simple rainfall-runoff model for the single and long term hydrological performance of green roofs

    DEFF Research Database (Denmark)

    Locatelli, Luca; Mark, Ole; Mikkelsen, Peter Steen

    Green roofs are being widely implemented for storm water control and runoff reduction. There is need for incorporating green roofs into urban drainage models in order to evaluate their impact. These models must have low computational costs and fine time resolution. This paper aims to develop...... a model of green roof hydrological performance. A simple conceptual model for the long term and single event hydrological performance of green roofs, shows to be capable of reproducing observed runoff measurements. The model has surface and subsurface storage components representing the overall retention...... capacity of the green roof. The runoff from the system is described by the non-linear reservoir method and the storage capacity of the green roof is continuously re-established by evapotranspiration. Runoff data from a green roof in Denmark are collected and used for parameter calibration....

  2. A Simple Differential Mode EMI Suppressor for the LLCL-Filter-Based Single-Phase Grid-Tied Transformerless Inverter

    DEFF Research Database (Denmark)

    Ji, Junhao; Wu, Weimin; He, Yuanbin

    2015-01-01

    The single-phase power converter topologies evolving of photovoltaic applications are still including passive filters, like the LCLor LLCL-filter. Compared with the LCL-filter, the total inductance of the LLCL-filter can be reduced a lot. However, due to the resonant inductor in series...... with the bypass capacitor, the differential mode (DM) electromagnetic interference (EMI) noise attenuation of an LLCL-filter-based grid-tied inverter declines. Conventionally, a capacitor was inserted in parallel with the LC resonant circuit branch of the LLCL-filter to suppress the DM EMI noise. In order...... to achieve a small value of capacitor as well as to minimize the additional reactive power, a novel simple DM EMI suppressor for the LLCL-filter-based system is proposed. The characters of two kinds of DM EMI suppressor are analyzed and compared in detail. Simulations and experiments on a 0.5-kW 110-V/50-Hz...

  3. A simple method for encapsulating single cells in alginate microspheres allows for direct PCR and whole genome amplification.

    Directory of Open Access Journals (Sweden)

    Saharnaz Bigdeli

    Full Text Available Microdroplets are an effective platform for segregating individual cells and amplifying DNA. However, a key challenge is to recover the contents of individual droplets for downstream analysis. This paper offers a method for embedding cells in alginate microspheres and performing multiple serial operations on the isolated cells. Rhodobacter sphaeroides cells were diluted in alginate polymer and sprayed into microdroplets using a fingertip aerosol sprayer. The encapsulated cells were lysed and subjected either to conventional PCR, or whole genome amplification using either multiple displacement amplification (MDA or a two-step PCR protocol. Microscopic examination after PCR showed that the lumen of the occupied microspheres contained fluorescently stained DNA product, but multiple displacement amplification with phi29 produced only a small number of polymerase colonies. The 2-step WGA protocol was successful in generating fluorescent material, and quantitative PCR from DNA extracted from aliquots of microspheres suggested that the copy number inside the microspheres was amplified up to 3 orders of magnitude. Microspheres containing fluorescent material were sorted by a dilution series and screened with a fluorescent plate reader to identify single microspheres. The DNA was extracted from individual isolates, re-amplified with full-length sequencing adapters, and then a single isolate was sequenced using the Illumina MiSeq platform. After filtering the reads, the only sequences that collectively matched a genome in the NCBI nucleotide database belonged to R. sphaeroides. This demonstrated that sequencing-ready DNA could be generated from the contents of a single microsphere without culturing. However, the 2-step WGA strategy showed limitations in terms of low genome coverage and an uneven frequency distribution of reads across the genome. This paper offers a simple method for embedding cells in alginate microspheres and performing PCR on isolated

  4. A simple method for the quantification of benzodiazepine receptors using iodine-123 iomazenil and single-photon emission tomography

    International Nuclear Information System (INIS)

    Ito, Hiroshi; Goto, Ryoui; Koyama, Masamichi; Kawashima, Ryuta; Ono, Shuichi; Sato, Kazunori; Fukuda, Hiroshi

    1996-01-01

    Iodine-123 iomazenil (Iomazenil) is a ligand for central type benzodiazepine receptors that is suitable for single-photon emission tomography (SPET). The purpose of this study was to develop a simple method for the quantification of its binding potential (BP). The method is based on a two-compartment model (K 1 , influx rate constant; k 2 ', efflux rate constant; V T '(=K 1 /k 2 '), the total distribution volumes relative to the total arterial tracer concentration), and requires two SPET scans and one blood sampling. For a given input function, the radioactivity ratio of the early to delayed scans can be considered to tabulate as a function of k 2 ', and a table lookup procedure provides the corresponding k 2 ' value, from which K 1 and V t ' values are then calculated. The arterial input function is obtained by calibration of the standard input function by the single blood sampling. SPET studies were performed on 14 patients with cerebrovascular diseases, dementia or brain tumours (mean age ±SD, 56.0±12.2). None of the patients had any heart, renal or liver disease. A dynamic SPET scan was performed following intravenous bolus injection of Iomazenil. A static SPET scan was performed at 180 min after injection. Frequent blood sampling from the brachial artery was performed on all subjects for determination of the arterial input function. Two-compartment model analysis was validated for calculation of the V T ' value of Iomazenil. Good correlations were observed between V T ' values calculated by three-compartment model analysis and those calculated by the present method, in which the scan time combinations (early scan/delayed scan) used were 15/180 min, 30/180 min or 45/180 min (all combinations: r=0.92), supporting the validity of this method. The present method is simple and applicable for clinical use. (orig.)

  5. Long-term results of single-session percutaneous drainage and ethanol sclerotherapy in simple renal cysts

    International Nuclear Information System (INIS)

    Akinci, Devrim; Akhan, Okan; Ozmen, Mustafa; Gumus, Burcak; Ozkan, Orhan; Karcaaltincaba, Musturay; Cil, Barbaros; Haliloglu, Mithat

    2005-01-01

    Purpose: To demonstrate the efficacy and long-term results of the single-session ethanol sclerotherapy in simple renal cysts. Materials and methods: Ninety-eight cysts in 97 patients (range: 18-76 years; mean age, 54 years) were included in the study. Indications were determined as flank pain in 74, hydronephrosis in 12, hypertension in 8, patient reassurance due to increasing cyst size in three patients. Mean follow-up period was 24.4 months. Procedures were performed with the guidance of fluoroscopy and ultrasonography at all times using 5-7 Fr pigtail catheters. After the cystogram that was obtained in all cases, 95% ethanol with a volume of 30-40% of the cyst volume was used as a sclerosing agent on an outpatient basis. Maximum volume of the injected ethanol was 200 ml. Follow-up examinations were performed 1, 3, 6 and 12 months after the procedure and once every year thereafter. Results: Average cyst volume reduction was 93% at the end of the first year. The cysts disappeared completely in 17 (17.5%) patients. After the procedure, in 67 (90%) patients improvement in flank pain was noted. Sixty-one (82%) patients were free of pain and in 6 (8%) of them the pain decreased. Normotension was obtained in 7 (87.5%) of the 8 hypertensive patients and no hydronephrosis was detected in 10 (83.3%) of the 12 patients after the procedure. Second intervention was required in 2 (2%) patients due to recurrence of cysts and related symptoms. One (1%) patient had small retroperitoneal hematoma that resolved spontaneously and in another (1%) patient spontaneous hemorrhage was detected into the cyst 1 year after the procedure. No other complication was detected during the procedure and follow-up. Conclusion: Percutaneous treatment of simple renal cysts with single-session sclerotherapy is a safe, effective and minimally invasive procedure and can be used as an alternative to multiple-session sclerotherapy with comparable results. High volume, up to 200 ml ethanol can be used

  6. Long-term results of single-session percutaneous drainage and ethanol sclerotherapy in simple renal cysts

    Energy Technology Data Exchange (ETDEWEB)

    Akinci, Devrim [Department of Radiology, School of Medicine, Hacettepe University, Shhiye, Ankara TR-06100 (Turkey)]. E-mail: akincid@hotmail.com; Akhan, Okan [Department of Radiology, School of Medicine, Hacettepe University, Shhiye, Ankara TR-06100 (Turkey); Ozmen, Mustafa [Department of Radiology, School of Medicine, Hacettepe University, Shhiye, Ankara TR-06100 (Turkey); Gumus, Burcak [Department of Radiology, School of Medicine, Hacettepe University, Shhiye, Ankara TR-06100 (Turkey); Ozkan, Orhan [Department of Radiology, School of Medicine, Hacettepe University, Shhiye, Ankara TR-06100 (Turkey); Karcaaltincaba, Musturay [Department of Radiology, School of Medicine, Hacettepe University, Shhiye, Ankara TR-06100 (Turkey); Cil, Barbaros [Department of Radiology, School of Medicine, Hacettepe University, Shhiye, Ankara TR-06100 (Turkey); Haliloglu, Mithat [Department of Radiology, School of Medicine, Hacettepe University, Shhiye, Ankara TR-06100 (Turkey)

    2005-05-01

    Purpose: To demonstrate the efficacy and long-term results of the single-session ethanol sclerotherapy in simple renal cysts. Materials and methods: Ninety-eight cysts in 97 patients (range: 18-76 years; mean age, 54 years) were included in the study. Indications were determined as flank pain in 74, hydronephrosis in 12, hypertension in 8, patient reassurance due to increasing cyst size in three patients. Mean follow-up period was 24.4 months. Procedures were performed with the guidance of fluoroscopy and ultrasonography at all times using 5-7 Fr pigtail catheters. After the cystogram that was obtained in all cases, 95% ethanol with a volume of 30-40% of the cyst volume was used as a sclerosing agent on an outpatient basis. Maximum volume of the injected ethanol was 200 ml. Follow-up examinations were performed 1, 3, 6 and 12 months after the procedure and once every year thereafter. Results: Average cyst volume reduction was 93% at the end of the first year. The cysts disappeared completely in 17 (17.5%) patients. After the procedure, in 67 (90%) patients improvement in flank pain was noted. Sixty-one (82%) patients were free of pain and in 6 (8%) of them the pain decreased. Normotension was obtained in 7 (87.5%) of the 8 hypertensive patients and no hydronephrosis was detected in 10 (83.3%) of the 12 patients after the procedure. Second intervention was required in 2 (2%) patients due to recurrence of cysts and related symptoms. One (1%) patient had small retroperitoneal hematoma that resolved spontaneously and in another (1%) patient spontaneous hemorrhage was detected into the cyst 1 year after the procedure. No other complication was detected during the procedure and follow-up. Conclusion: Percutaneous treatment of simple renal cysts with single-session sclerotherapy is a safe, effective and minimally invasive procedure and can be used as an alternative to multiple-session sclerotherapy with comparable results. High volume, up to 200 ml ethanol can be used

  7. A simple, single-substrate model to interpret intra-annual stable isotope signals in tree-ring cellulose

    Science.gov (United States)

    Ogée, J.; Barbour, M. M.; Wingate, L.; Bert, D.; Bosc, A.; Stievenard, M.; Lambrot, C.; Pierre, M.; Bariac, T.; Dewar, R. C.

    2009-04-01

    High-resolution intra-annual measurements of the carbon and oxygen stable isotope composition of cellulose in annual tree rings (δ13Ccellulose and δ18Ocellulose, respectively) reveal well-defined seasonal patterns that could contain valuable records of past climate and tree function. Interpreting these signals is nonetheless complex because they not only record the signature of current assimilates, but also depend on carbon allocation dynamics within the trees. Here, we present a simple, single-substrate model for wood growth containing only 12 main parameters. The model is used to interpret an isotopic intra-annual chronology collected in an even-aged maritime pine plantation growing in the South-West of France, where climate, soil and flux variables were also monitored. The empirical δ13Ccellulose and δ18Ocellulose exhibit dynamic seasonal patterns, with clear differences between years and individuals, that are mostly captured by the model. In particular, the amplitude of both signals is reproduced satisfactorily as well as the sharp 18O enrichment at the beginning of 1997 and the less pronounced 13C and 18O depletion observed at the end of the latewood. Our results suggest that the single-substrate hypothesis is a good approximation for tree ring studies on Pinus pinaster, at least for the environmental conditions covered by this study. A sensitivity analysis revealed that, in the early wood, the model was particularly sensitive to the date when cell wall thickening begins (twt). We therefore propose to use the model to reconstruct time series of twt and explore how climate influences this key parameter of xylogenesis.

  8. A Simple Fractionated Extraction Method for the Comprehensive Analysis of Metabolites, Lipids, and Proteins from a Single Sample.

    Science.gov (United States)

    Salem, Mohamed; Bernach, Michal; Bajdzienko, Krzysztof; Giavalisco, Patrick

    2017-06-01

    Understanding of complex biological systems requires the measurement, analysis and integration of multiple compound classes of the living cell, usually determined by transcriptomic, proteomic, metabolomics and lipidomic measurements. In this protocol, we introduce a simple method for the reproducible extraction of metabolites, lipids and proteins from biological tissues using a single aliquot per sample. The extraction method is based on a methyl tert-butyl ether: methanol: water system for liquid: liquid partitioning of hydrophobic and polar metabolites into two immiscible phases along with the precipitation of proteins and other macromolecules as a solid pellet. This method, therefore, provides three different fractions of specific molecular composition, which are fully compatible with common high throughput 'omics' technologies such as liquid chromatography (LC) or gas chromatography (GC) coupled to mass spectrometers. Even though the method was initially developed for the analysis of different plant tissue samples, it has proved to be fully compatible for the extraction and analysis of biological samples from systems as diverse as algae, insects, and mammalian tissues and cell cultures.

  9. Simple unification

    International Nuclear Information System (INIS)

    Ponce, W.A.; Zepeda, A.

    1987-08-01

    We present the results obtained from our systematic search of a simple Lie group that unifies weak and electromagnetic interactions in a single truly unified theory. We work with fractionally charged quarks, and allow for particles and antiparticles to belong to the same irreducible representation. We found that models based on SU(6), SU(7), SU(8) and SU(10) are viable candidates for simple unification. (author). 23 refs

  10. An Evaluation of the Value of Choice-Making Opportunities in Single-Operant Arrangements: Simple Fixed- and Progressive-Ratio Schedules

    Science.gov (United States)

    Tiger, Jeffrey H.; Toussaint, Karen A.; Roath, Christopher T.

    2010-01-01

    The current study compared the effects of choice and no-choice reinforcement conditions on the task responding of 3 children with autism across 2 single-operant paradigm reinforcer assessments. The first assessment employed simple fixed-ratio (FR) schedules; the second used progressive-ratio (PR) schedules. The latter assessment identified the…

  11. Global Application of TaiWan Ionospheric Model to Single-Frequency GPS Positioning

    Science.gov (United States)

    Macalalad, E.; Tsai, L. C.; Wu, J.

    2012-04-01

    Ionospheric delay is one the major sources of error in GPS positioning and navigation. This error in both pseudorange and phase ranges vary depending on the location of observation, local time, season, solar cycle and geomagnetic activity. For single-frequency receivers, this delay is usually removed using ionospheric models. Two of them are the Klobuchar, or broadcast, model and the global ionosphere map (GIM) provided by the International GNSS Service (IGS). In this paper, a three dimensional ionospheric electron (ne) density model derived from FormoSat3/COSMIC GPS Radio Occultation measurements, called the TaiWan Ionosphere Model, is used. It was used to calculate the slant total electron content (STEC) between receiver and GPS satellites to correct the pseudorange single-frequency observations. The corrected pseudorange for every epoch was used to determine a more accurate position of the receiver. Observations were made in July 2, 2011(Kp index = 0-2) in five randomly selected sites across the globe, four of which are IGS stations (station ID: cnmr, coso, irkj and morp) while the other is a low-cost single-frequency receiver located in Chungli City, Taiwan (ID: isls). It was illustrated that TEC maps generated using TWIM exhibited a detailed structure of the ionosphere, whereas Klobuchar and GIM only provided the basic diurnal and geographic features of the ionosphere. Also, it was shown that for single-frequency static point positioning TWIM provides more accurate and more precise positioning than the Klobuchar and GIM models for all stations. The average %error of the corrections made by Klobuchar, GIM and TWIM in DRMS are 3.88%, 0.78% and 17.45%, respectively. While the average %error in VRMS for Klobuchar, GIM and TWIM are 53.55%, 62.09%, 66.02%, respectively. This shows the capability of TWIM to provide a good global 3-dimensional ionospheric model.

  12. Performance Considerations for the SIMPL Single Photon, Polarimetric, Two-Color Laser Altimeter as Applied to Measurements of Forest Canopy Structure and Composition

    Science.gov (United States)

    Dabney, Philip W.; Harding, David J.; Valett, Susan R.; Vasilyev, Aleksey A.; Yu, Anthony W.

    2012-01-01

    The Slope Imaging Multi-polarization Photon-counting Lidar (SIMPL) is a multi-beam, micropulse airborne laser altimeter that acquires active and passive polarimetric optical remote sensing measurements at visible and near-infrared wavelengths. SIMPL was developed to demonstrate advanced measurement approaches of potential benefit for improved, more efficient spaceflight laser altimeter missions. SIMPL data have been acquired for wide diversity of forest types in the summers of 2010 and 2011 in order to assess the potential of its novel capabilities for characterization of vegetation structure and composition. On each of its four beams SIMPL provides highly-resolved measurements of forest canopy structure by detecting single-photons with 15 cm ranging precision using a narrow-beam system operating at a laser repetition rate of 11 kHz. Associated with that ranging data SIMPL provides eight amplitude parameters per beam unlike the single amplitude provided by typical laser altimeters. Those eight parameters are received energy that is parallel and perpendicular to that of the plane-polarized transmit pulse at 532 nm (green) and 1064 nm (near IR), for both the active laser backscatter retro-reflectance and the passive solar bi-directional reflectance. This poster presentation will cover the instrument architecture and highlight the performance of the SIMPL instrument with examples taken from measurements for several sites with distinct canopy structures and compositions. Specific performance areas such as probability of detection, after pulsing, and dead time, will be highlighted and addressed, along with examples of their impact on the measurements and how they limit the ability to accurately model and recover the canopy properties. To assess the sensitivity of SIMPL's measurements to canopy properties an instrument model has been implemented in the FLIGHT radiative transfer code, based on Monte Carlo simulation of photon transport. SIMPL data collected in 2010 over

  13. Extracting 3D layout from a single image using global image structures.

    Science.gov (United States)

    Lou, Zhongyu; Gevers, Theo; Hu, Ninghang

    2015-10-01

    Extracting the pixel-level 3D layout from a single image is important for different applications, such as object localization, image, and video categorization. Traditionally, the 3D layout is derived by solving a pixel-level classification problem. However, the image-level 3D structure can be very beneficial for extracting pixel-level 3D layout since it implies the way how pixels in the image are organized. In this paper, we propose an approach that first predicts the global image structure, and then we use the global structure for fine-grained pixel-level 3D layout extraction. In particular, image features are extracted based on multiple layout templates. We then learn a discriminative model for classifying the global layout at the image-level. Using latent variables, we implicitly model the sublevel semantics of the image, which enrich the expressiveness of our model. After the image-level structure is obtained, it is used as the prior knowledge to infer pixel-wise 3D layout. Experiments show that the results of our model outperform the state-of-the-art methods by 11.7% for 3D structure classification. Moreover, we show that employing the 3D structure prior information yields accurate 3D scene layout segmentation.

  14. Obtaining Global Picture From Single Point Observations by Combining Data Assimilation and Machine Learning Tools

    Science.gov (United States)

    Shprits, Y.; Zhelavskaya, I. S.; Kellerman, A. C.; Spasojevic, M.; Kondrashov, D. A.; Ghil, M.; Aseev, N.; Castillo Tibocha, A. M.; Cervantes Villa, J. S.; Kletzing, C.; Kurth, W. S.

    2017-12-01

    Increasing volume of satellite measurements requires deployment of new tools that can utilize such vast amount of data. Satellite measurements are usually limited to a single location in space, which complicates the data analysis geared towards reproducing the global state of the space environment. In this study we show how measurements can be combined by means of data assimilation and how machine learning can help analyze large amounts of data and can help develop global models that are trained on single point measurement. Data Assimilation: Manual analysis of the satellite measurements is a challenging task, while automated analysis is complicated by the fact that measurements are given at various locations in space, have different instrumental errors, and often vary by orders of magnitude. We show results of the long term reanalysis of radiation belt measurements along with fully operational real-time predictions using data assimilative VERB code. Machine Learning: We present application of the machine learning tools for the analysis of NASA Van Allen Probes upper-hybrid frequency measurements. Using the obtained data set we train a new global predictive neural network. The results for the Van Allen Probes based neural network are compared with historical IMAGE satellite observations. We also show examples of predictions of geomagnetic indices using neural networks. Combination of machine learning and data assimilation: We discuss how data assimilation tools and machine learning tools can be combine so that physics-based insight into the dynamics of the particular system can be combined with empirical knowledge of it's non-linear behavior.

  15. A simple global representation for second-order normal forms of Hamiltonian systems relative to periodic flows

    International Nuclear Information System (INIS)

    Avendaño-Camacho, M; Vallejo, J A; Vorobjev, Yu

    2013-01-01

    We study the determination of the second-order normal form for perturbed Hamiltonians relative to the periodic flow of the unperturbed Hamiltonian H 0 . The formalism presented here is global, and can be easily implemented in any computer algebra system. We illustrate it by means of two examples: the Hénon–Heiles and the elastic pendulum Hamiltonians. (paper)

  16. Will Global Warming Cause a Rise in Sea Level? A Simple Activity about the States of Water

    Science.gov (United States)

    Oguz, Ayse

    2009-01-01

    In this activity, a possible problem related to global warming is clarified by the principle of states of water. The activity consists of an experiment that includes three scientific principles: Archimedes' Principle, the Law of Conservation of Matter, and the fluidity of liquids. The experiment helps students raise questions and open new horizons…

  17. DNA detection and single nucleotide mutation identification using SERS for molecular diagnostics and global health

    Science.gov (United States)

    Ngo, Hoan T.; Gandra, Naveen; Fales, Andrew M.; Taylor, Steve M.; Vo-Dinh, Tuan

    2017-02-01

    Nucleic acid-based molecular diagnostics at the point-of-care (POC) and in resource-limited settings is still a challenge. We present a sensitive yet simple DNA detection method with single nucleotide polymorphism (SNP) identification capability. The detection scheme involves sandwich hybridization of magnetic beads conjugated with capture probes, target sequences, and ultrabright surface-enhanced Raman Scattering (SERS) nanorattles conjugated with reporter probes. Upon hybridization, the sandwich probes are concentrated at the detection focus controlled by a magnetic system for SERS measurements. The ultrabright SERS nanorattles, consisting of a core and a shell with resonance Raman reporters loaded in the gap space between the core and the shell, serve as SERS tags for ultrasensitive signal detection. Specific DNA sequences of the malaria parasite Plasmodium falciparum and dengue virus 1 (DENV1) were used as the model marker system. Detection limit of approximately 100 attomoles was achieved. Single nucleotide polymorphism (SNP) discrimination of wild type malaria DNA and mutant malaria DNA, which confers resistance to artemisinin drugs, was also demonstrated. The results demonstrate the molecular diagnostic potential of the nanorattle-based method to both detect and genotype infectious pathogens. The method's simplicity makes it a suitable candidate for molecular diagnosis at the POC and in resource-limited settings.

  18. Single Image Super-Resolution Using Global Regression Based on Multiple Local Linear Mappings.

    Science.gov (United States)

    Choi, Jae-Seok; Kim, Munchurl

    2017-03-01

    Super-resolution (SR) has become more vital, because of its capability to generate high-quality ultra-high definition (UHD) high-resolution (HR) images from low-resolution (LR) input images. Conventional SR methods entail high computational complexity, which makes them difficult to be implemented for up-scaling of full-high-definition input images into UHD-resolution images. Nevertheless, our previous super-interpolation (SI) method showed a good compromise between Peak-Signal-to-Noise Ratio (PSNR) performances and computational complexity. However, since SI only utilizes simple linear mappings, it may fail to precisely reconstruct HR patches with complex texture. In this paper, we present a novel SR method, which inherits the large-to-small patch conversion scheme from SI but uses global regression based on local linear mappings (GLM). Thus, our new SR method is called GLM-SI. In GLM-SI, each LR input patch is divided into 25 overlapped subpatches. Next, based on the local properties of these subpatches, 25 different local linear mappings are applied to the current LR input patch to generate 25 HR patch candidates, which are then regressed into one final HR patch using a global regressor. The local linear mappings are learned cluster-wise in our off-line training phase. The main contribution of this paper is as follows: Previously, linear-mapping-based conventional SR methods, including SI only used one simple yet coarse linear mapping to each patch to reconstruct its HR version. On the contrary, for each LR input patch, our GLM-SI is the first to apply a combination of multiple local linear mappings, where each local linear mapping is found according to local properties of the current LR patch. Therefore, it can better approximate nonlinear LR-to-HR mappings for HR patches with complex texture. Experiment results show that the proposed GLM-SI method outperforms most of the state-of-the-art methods, and shows comparable PSNR performance with much lower

  19. Genotypic distribution of single nucleotide polymorphisms in oral cancer: global scene.

    Science.gov (United States)

    Multani, Shaleen; Saranath, Dhananjaya

    2016-11-01

    Globocan 2012 reports the global oral cancer incidence of 300,373 new oral cancer cases annually, contributing to 2.1 % of the world cancer burden. The major well-established risk factors for oral cancer include tobacco, betel/areca nut, alcohol and high-risk oncogenic human papilloma virus (HPV) 16/18. However, only 5-10 % of individuals with high-risk lifestyle develop oral cancer. Thus, genomic variants in individuals represented as single nucleotide polymorphisms (SNPs) influence susceptibility to oral cancer. With a view to understanding the role of genomic variants in oral cancer, we reviewed SNPs in case-control studies with a minimum of 100 cases and 100 controls. PubMed and HuGE navigator search engines were used to obtain data published from 1990 to 2015, which identified 67 articles investigating the role of SNPs in oral cancer. Single publications reported 93 SNPs in 55 genes, with 34 SNPs associated with a risk of oral cancer. Meta-analysis of data in multiple studies defined nine SNPs associated with a risk of oral cancer. The genes were associated with critical functions deregulated in cancers, including cell proliferation, immune function, inflammation, transcription, DNA repair and xenobiotic metabolism.

  20. Percutaneous Treatment of Simple Hepatic Cysts: The Long-Term Results of PAIR and Catheterization Techniques as Single-Session Procedures

    International Nuclear Information System (INIS)

    Akhan, Okan; Islim, Filiz; Balci, Sinan; Erbahceci, Aysun; Akpınar, Burcu; Ciftci, Turkmen; Akinci, Devrim

    2016-01-01

    PurposeThe purpose of our study is to evaluate results of percutaneous aspiration with alcohol sclerotherapy in symptomatic patients with simple hepatic cysts by employing single-session techniques either by a needle or a catheter.Materials and MethodsWe retrospectively included 39 simple hepatic cysts in 35 patients treated via percutaneous aspiration and single-session alcohol sclerotherapy between years 1993 and 2012. Indications were pain (n = 28) or ruling out cystic echinococcus (CE) disease (n = 7). 29 cysts in 26 patients were treated by needle technique (Group A) and ten cysts in nine patients were treated by single-session catheter technique (Group B). Patients were followed for 4–173 months (median: 38 months).ResultsAll patients were successfully treated. Before procedure, cyst volumes were 21–676 cc (median: 94 cc). Post-procedure cyst volumes at last follow-up were 0-40 cc (median: 1 cc). The mean decrease in cyst volume was 95.92 ± 2.86 % in all patients (95.96 ± 3.26 % in Group A and 95.80 ± 6.20 % in Group B). There was no statistically significant difference between the volume reduction rates of Group A and Group B. Only one patient, in Group B, developed a major complication, an abscess. Hospitalization period was 1 day for all patients.ConclusionsFor patients with symptomatic simple hepatic cysts smaller than 500 cc in volume by using puncture, aspiration, injection, and reaspiration (PAIR) technique with only needle, single-session alcohol sclerotherapy of 10 min is a safe and effective procedure with high success rate.

  1. Percutaneous Treatment of Simple Hepatic Cysts: The Long-Term Results of PAIR and Catheterization Techniques as Single-Session Procedures

    Energy Technology Data Exchange (ETDEWEB)

    Akhan, Okan, E-mail: akhano@tr.net [Hacettepe University Faculty of Medicine, Department of Radiology (Turkey); Islim, Filiz, E-mail: fislim@yahoo.com [Istanbul Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Department of Radiology (Turkey); Balci, Sinan, E-mail: snnbalci@gmail.com [Hacettepe University Faculty of Medicine, Department of Radiology (Turkey); Erbahceci, Aysun, E-mail: aysunerbahceci@yahoo.com [Istanbul Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Department of Radiology (Turkey); Akpınar, Burcu, E-mail: burcu-akpinar@yahoo.com; Ciftci, Turkmen, E-mail: turkmenciftci@yahoo.com; Akinci, Devrim, E-mail: akincid@hotmail.com [Hacettepe University Faculty of Medicine, Department of Radiology (Turkey)

    2016-06-15

    PurposeThe purpose of our study is to evaluate results of percutaneous aspiration with alcohol sclerotherapy in symptomatic patients with simple hepatic cysts by employing single-session techniques either by a needle or a catheter.Materials and MethodsWe retrospectively included 39 simple hepatic cysts in 35 patients treated via percutaneous aspiration and single-session alcohol sclerotherapy between years 1993 and 2012. Indications were pain (n = 28) or ruling out cystic echinococcus (CE) disease (n = 7). 29 cysts in 26 patients were treated by needle technique (Group A) and ten cysts in nine patients were treated by single-session catheter technique (Group B). Patients were followed for 4–173 months (median: 38 months).ResultsAll patients were successfully treated. Before procedure, cyst volumes were 21–676 cc (median: 94 cc). Post-procedure cyst volumes at last follow-up were 0-40 cc (median: 1 cc). The mean decrease in cyst volume was 95.92 ± 2.86 % in all patients (95.96 ± 3.26 % in Group A and 95.80 ± 6.20 % in Group B). There was no statistically significant difference between the volume reduction rates of Group A and Group B. Only one patient, in Group B, developed a major complication, an abscess. Hospitalization period was 1 day for all patients.ConclusionsFor patients with symptomatic simple hepatic cysts smaller than 500 cc in volume by using puncture, aspiration, injection, and reaspiration (PAIR) technique with only needle, single-session alcohol sclerotherapy of 10 min is a safe and effective procedure with high success rate.

  2. Measuring Globalization

    OpenAIRE

    Andersen, Torben M.; Herbertsson, Tryggvi Thor

    2003-01-01

    The multivariate technique of factor analysis is used to combine several indicators of economic integration and international transactions into a single measure or index of globalization. The index is an alternative to the simple measure of openness based on trade, and it produces a ranking of countries over time for 23 OECD countries. Ireland is ranked as the most globalized country during the 1990?s, while the UK was at the top during the 1980?s. Some of the most notable changes in the rank...

  3. Globalization

    Directory of Open Access Journals (Sweden)

    Tulio Rosembuj

    2006-12-01

    Full Text Available There is no singular globalization, nor is the result of an individual agent. We could start by saying that global action has different angles and subjects who perform it are different, as well as its objectives. The global is an invisible invasion of materials and immediate effects.

  4. Globalization

    OpenAIRE

    Tulio Rosembuj

    2006-01-01

    There is no singular globalization, nor is the result of an individual agent. We could start by saying that global action has different angles and subjects who perform it are different, as well as its objectives. The global is an invisible invasion of materials and immediate effects.

  5. A low-cost phantom for simple routine testing of single photon emission computed tomography (SPECT) cameras

    International Nuclear Information System (INIS)

    Ng, A.H.; Ng, K.H.; Dharmendra, H.; Perkins, A.C.

    2009-01-01

    A simple sphere test phantom has been developed for routine performance testing of SPECT systems in situations where expensive commercial phantoms may not be available. The phantom was based on a design with six universal syringe hubs set in the frame to support a circular array of six glass blown spheres of different sizes. The frame was then placed into a water-filled CT abdomen phantom and scanned with a triple head camera system (Philips IRIX TM , USA). Comparison was made with a commercially available phantom (Deluxe Jaszczak phantom). Whereas the commercial phantom demonstrates cold spot resolution, an important advantage of the sphere test phantom was that hot spot resolution could be easily measured using almost half (370 MBq) of the activity recommended for use in the commercial phantom. Results showed that the contrast increased non-linearly with sphere volume and radionuclide concentration. The phantom was found to be suitable as an inexpensive option for daily performance tests.

  6. Simple convergent-nozzle aerosol injector for single-particle diffractive imaging with X-ray free-electron lasers

    Directory of Open Access Journals (Sweden)

    R. A. Kirian

    2015-07-01

    Full Text Available A major challenge in high-resolution x-ray free-electron laser-based coherent diffractive imaging is the development of aerosol injectors that can efficiently deliver particles to the peak intensity of the focused X-ray beam. Here, we consider the use of a simple convergent-orifice nozzle for producing tightly focused beams of particles. Through optical imaging we show that 0.5 μm particles can be focused to a full-width at half maximum diameter of 4.2 μm, and we demonstrate the use of such a nozzle for injecting viruses into a micro-focused soft-X-ray FEL beam.

  7. High-dose nifuratel for simple and mixed aerobic vaginitis: A single-center prospective open-label cohort study.

    Science.gov (United States)

    Liang, Qian; Li, Nan; Song, Shurong; Zhang, Aihua; Li, Ni; Duan, Ying

    2016-10-01

    The efficacy and safety of two nifuratel dosages for the treatment of aerobic vaginitis (AV) were compared. This was a prospective open-label cohort study of patients diagnosed and treated at the Tianjin Third Central Hospital between January 2012 and December 2013. The co-presence of bacterial vaginosis (BV), vulvovaginal candidiasis (VVC), or/and trichomonal vaginitis (TV; mixed AV) was determined. Patients were randomized to nifuratel-500 (500 mg nifuratel, intravaginal, 10 days) or nifuratel-250 (250 mg nifuratel, intravaginal, 10 days), and followed-up for three to seven days after treatment completion. Primary and secondary outcomes were recovery rate and adverse events, respectively. The study included 142 patients with AV. Age was not significantly different between the groups (n = 71 each), and disease distribution was identical: 29 (40.85%) simple AV and 42 (59.15%) mixed AV (AV + BV, 42.86 %; AV + VVC, 30.95%; AV + TV, 26.19%). In patients with simple AV, the recovery rate did not differ significantly between the nifuratel-500 (26/29, 89.66%) and nifuratel-250 (22/29, 75.86%) groups. In patients with mixed AV, recovery rates were significantly higher in the nifuratel-500 than in the nifuratel-250 group (AV + BV, 88.89% vs 50.00 %; AV + VVC, 76.92 % vs 30.77 %; AV + TV, 90.91 % vs 36.36%; all P < 0.05). Only one patient (nifuratel-500) reported an adverse event (mild anaphylactic reaction). Nifuratel 500 mg showed good clinical efficacy for the treatment of AV, particularly mixed AV, and is superior to the 250 mg dosage in the treatment of mixed AV. © 2016 Japan Society of Obstetrics and Gynecology.

  8. A Simple and Consistent Equation of State for Sodium in the Single Phase and Two Phase Regions

    International Nuclear Information System (INIS)

    Breton, J.P.

    1976-01-01

    An equation of state valid over an extended temperature and density range has been derived. Then, the following properties have been deduced: coefficient of thermal expansion, isothermal coefficient of bulk compressibility, thermal pressure coefficient, heat capacity at constant pressure, at constant volume, along the saturation curve for liquid, for vapor, heat of vaporization, speed of sound, and finally the Mollier diagram and the entropy diagram. All the obtained properties are thermodynamically consistent and satisfy the basic relations of thermodynamics for both single phase and two-phase regions. Experimental results were always used when available

  9. A simple and consistent equation of state for sodium in the single phase and two phase regions

    International Nuclear Information System (INIS)

    Breton, J.P.

    1976-01-01

    An equation of state valid over an extended temperature and density range has been derived. Then, the following properties have been deduced : coefficient of thermal expansion, isothermal coefficient of bulk compressibility, thermal pressure coefficient, heat capacity at constant pressure, at constant volume, along the saturation curve for liquid, for vapor, heat of vaporization, speed of sound, and finally the Mollier diagram and the entropy diagram. All the obtained properties are thermodynamically consistent and satisfy the basic relations of thermodynamics for both single phase and two-phase regions. Experimental results were always used when available. (auth.)

  10. Simple die pressing for making artificial holes in single-grain Gd1.5Ba2Cu3O7−y superconductors

    International Nuclear Information System (INIS)

    Kim, K-M; Park, S-D; Jun, B-H; Kim, C-J; Ko, T K

    2012-01-01

    The presence of artificial holes in single-grain REBa 2 Cu 3 O 7−y (RE123, RE: rare-earth elements) bulk superconductors can facilitate oxygen diffusion into superconducting grains through the increased surface area. In addition to the enhancement of oxygen diffusion, the mechanical properties and thermal conductivity of bulk superconductors can be improved by filling holes with a metallic conductive phase. This study presents a new and simple hole-making process for single-grain RE123 bulk superconductors. Artificial holes 3 or 5 mm in diameter were made for Gd 1.5 Ba 2 Cu 3 O 7−y (Gd1.5) powder compacts prior to the sintering/melt growth process using specially designed pressing dies. The die pressing neither induced cracking in powder compacts nor influenced thermal procedures for the Gd123 growth. Single-grain Gd1.5 bulk superconductors with holes were successfully fabricated by a top-seeded melt growth (TSMG) process using Gd1.5 powder compacts with holes. The die pressing was proven as a time-saving process in comparison with the conventional method which makes holes in sintered or melt-processed hard bodies by mechanical drilling. The detailed fabrication process of single-grain Gd1.5 bulk superconductor with holes, magnetic levitation forces, and magnetic flux density, estimated for the single-grain Gd123 bulk superconductors with holes, are reported. (paper)

  11. Simple Adaptive Single Differential Coherence Detection of BPSK Signals in IEEE 802.15.4 Wireless Sensor Networks.

    Science.gov (United States)

    Zhang, Gaoyuan; Wen, Hong; Wang, Longye; Xie, Ping; Song, Liang; Tang, Jie; Liao, Runfa

    2017-12-26

    In this paper, we propose an adaptive single differential coherent detection (SDCD) scheme for the binary phase shift keying (BPSK) signals in IEEE 802.15.4 Wireless Sensor Networks (WSNs). In particular, the residual carrier frequency offset effect (CFOE) for differential detection is adaptively estimated, with only linear operation, according to the changing channel conditions. It was found that the carrier frequency offset (CFO) and chip signal-to-noise ratio (SNR) conditions do not need a priori knowledge. This partly benefits from that the combination of the trigonometric approximation sin - 1 ( x ) ≈ x and a useful assumption, namely, the asymptotic or high chip SNR, is considered for simplification of the full estimation scheme. Simulation results demonstrate that the proposed algorithm can achieve an accurate estimation and the detection performance can completely meet the requirement of the IEEE 802.15.4 standard, although with a little loss of reliability and robustness as compared with the conventional optimal single-symbol detector.

  12. Globalization

    OpenAIRE

    Andru?cã Maria Carmen

    2013-01-01

    The field of globalization has highlighted an interdependence implied by a more harmonious understanding determined by the daily interaction between nations through the inducement of peace and the management of streamlining and the effectiveness of the global economy. For the functioning of the globalization, the developing countries that can be helped by the developed ones must be involved. The international community can contribute to the institution of the development environment of the gl...

  13. Ocean acidification over the next three centuries using a simple global climate carbon-cycle model: projections and sensitivities

    Energy Technology Data Exchange (ETDEWEB)

    Hartin, Corinne A.; Bond-Lamberty, Benjamin; Patel, Pralit; Mundra, Anupriya

    2016-08-01

    Continued oceanic uptake of anthropogenic CO2 is projected to significantly alter the chemistry of the upper oceans over the next three centuries, with potentially serious consequences for marine ecosystems. Relatively few models have the capability to make projections of ocean acidification, limiting our ability to assess the impacts and probabilities of ocean changes. In this study we examine the ability of Hector v1.1, a reduced-form global model, to project changes in the upper ocean carbonate system over the next three centuries, and quantify the model's sensitivity to parametric inputs. Hector is run under prescribed emission pathways from the Representative Concentration Pathways (RCPs) and compared to both observations and a suite of Coupled Model Intercomparison (CMIP5) model outputs. Current observations confirm that ocean acidification is already taking place, and CMIP5 models project significant changes occurring to 2300. Hector is consistent with the observational record within both the high- (> 55°) and low-latitude oceans (< 55°). The model projects low-latitude surface ocean pH to decrease from preindustrial levels of 8.17 to 7.77 in 2100, and to 7.50 in 2300; aragonite saturation levels (ΩAr) decrease from 4.1 units to 2.2 in 2100 and 1.4 in 2300 under RCP 8.5. These magnitudes and trends of ocean acidification within Hector are largely consistent with the CMIP5 model outputs, although we identify some small biases within Hector's carbonate system. Of the parameters tested, changes in [H+] are most sensitive to parameters that directly affect atmospheric CO2 concentrations – Q10 (terrestrial respiration temperature response) as well as changes in ocean circulation, while changes in ΩAr saturation levels are sensitive to changes in ocean salinity and Q10. We conclude that Hector is a robust tool well suited for rapid ocean acidification

  14. A simple groundwater scheme in the TRIP river routing model: global off-line evaluation against GRACE terrestrial water storage estimates and observed river discharges

    Directory of Open Access Journals (Sweden)

    J.-P. Vergnes

    2012-10-01

    Full Text Available Groundwater is a non-negligible component of the global hydrological cycle, and its interaction with overlying unsaturated zones can influence water and energy fluxes between the land surface and the atmosphere. Despite its importance, groundwater is not yet represented in most climate models. In this paper, the simple groundwater scheme implemented in the Total Runoff Integrating Pathways (TRIP river routing model is applied in off-line mode at global scale using a 0.5° model resolution. The simulated river discharges are evaluated against a large dataset of about 3500 gauging stations compiled from the Global Data Runoff Center (GRDC and other sources, while the terrestrial water storage (TWS variations derived from the Gravity Recovery and Climate Experiment (GRACE satellite mission help to evaluate the simulated TWS. The forcing fields (surface runoff and deep drainage come from an independent simulation of the Interactions between Soil-Biosphere-Atmosphere (ISBA land surface model covering the period from 1950 to 2008. Results show that groundwater improves the efficiency scores for about 70% of the gauging stations and deteriorates them for 15%. The simulated TWS are also in better agreement with the GRACE estimates. These results are mainly explained by the lag introduced by the low-frequency variations of groundwater, which tend to shift and smooth the simulated river discharges and TWS. A sensitivity study on the global precipitation forcing used in ISBA to produce the forcing fields is also proposed. It shows that the groundwater scheme is not influenced by the uncertainties in precipitation data.

  15. Counting efficiencies by liquid scintillation counting. Single isomeric transitions; Eficiencia de recuento por centelleo liquido. Transiciones isomericas simples

    Energy Technology Data Exchange (ETDEWEB)

    Grau Carles, A.; Grau Malonda, A.

    1995-07-01

    In this work we present liquid scintillation counting efficiency tables for several radionuclides with single isomeric transitions, in which electron conversion and gamma emission processes are competitive. We study the radionuclides: 58mCo, 77mSe, 79mBr, 87mSr, S9mY, 93mNb, 103mRh, 107mAg, 109mAg, 113mIn, 131mXe, I33mXe, 135raBa, 137mBa, 167raEr, for two different scintillators, Ultima-Gold and Insta-Gel. We consider volumes of 10 and 15 mL for Ultima Gold, and 15 mL for Insta-Gel. (Author) 18 refs.

  16. Simple Objective Detection of Human Lyme Disease Infection Using Immuno-PCR and a Single Recombinant Hybrid Antigen

    Science.gov (United States)

    Halpern, Micah D.; Molins, Claudia R.; Schriefer, Martin

    2014-01-01

    A serology-based tiered approach has, to date, provided the most effective means of laboratory confirmation of clinically suspected cases of Lyme disease, but it lacks sensitivity in the early stages of disease and is often dependent on subjectively scored immunoblots. We recently demonstrated the use of immuno-PCR (iPCR) for detecting Borrelia burgdorferi antibodies in patient serum samples that were positive for Lyme disease. To better understand the performance of the Lyme disease iPCR assay, the repeatability and variability of the background of the assay across samples from a healthy population (n = 36) were analyzed. Both of these parameters were found to have coefficients of variation of Lyme disease patient serum samples (n = 12) demonstrated a strong correlation with that of 2-tier testing. Furthermore, a simplified iPCR approach using a single hybrid antigen and detecting only IgG antibodies confirmed the 2-tier diagnosis in the Lyme disease patient serum samples (n = 12). Validation of the hybrid antigen IgG iPCR assay using a blinded panel of Lyme disease and non-Lyme disease patient serum samples (n = 92) resulted in a sensitivity of 69% (95% confidence interval [CI], 50% to 84%), compared to that of the 2-tier analysis at 59% (95% CI, 41% to 76%), and a specificity of 98% (95% CI, 91% to 100%) compared to that of the 2-tier analysis at 97% (95% CI, 88% to 100%). A single-tier hybrid antigen iPCR assay has the potential to be an improved method for detecting host-generated antibodies against B. burgdorferi. PMID:24899074

  17. Synthesis of single-crystal PbS nanorods via a simple hydrothermal process using PEO-PPO-PEO triblock copolymer as a structure-directing agent

    International Nuclear Information System (INIS)

    Bu Junfu; Nie Chageng; Liang Jinxia; Sun Lan; Xie Zhaoxiong; Wu Qi; Lin Changjian

    2011-01-01

    Single-crystal PbS nanorods were successfully synthesized through a simple hydrothermal route using PEO-PPO-PEO triblock copolymer (P123) as a structure-directing agent. The XRD pattern indicates that the crystal structure of the nanorods is face-centre-cubic rocksalt. A SEM image shows that the nanorods have a diameter of 40-70 nm and a length of 200-600 nm, and both tips exhibit taper-like structures. HRTEM and SAED images reveal the single-crystalline nature of the nanorods with the growth along the (111) direction. The experimental results indicated that the P123 concentration and reaction temperature played important roles in controlling the morphology of the PbS nanostructures. The optical property of PbS nanorods was investigated by UV-Vis absorption spectroscopy and the band structure was calculated by the B3LYP hybrid density functional theory.

  18. A Simple Network to Remove Interference in Surface EMG Signal from Single Gene Affected Phenylketonuria Patients for Proper Diagnosis

    Science.gov (United States)

    Mohanty, Madhusmita; Basu, Mousumi; Pattanayak, Deba Narayan; Mohapatra, Sumant Kumar

    2018-04-01

    Recently Autosomal Recessive Single Gene (ARSG) diseases are highly effective to the children within the age of 5-10 years. One of the most ARSG disease is a Phenylketonuria (PKU). This single gene disease is associated with mutations in the gene that encodes the enzyme phenylalanine hydroxylase (PAH, Gene 612349). Through this mutation process, PAH of the gene affected patient can not properly manufacture PAH as a result the patients suffer from decreased muscle tone which shows abnormality in EMG signal. Here the extraction of the quality of the PKU affected EMG (PKU-EMG) signal is a keen interest, so it is highly necessary to remove the added ECG signal as well as the biological and instrumental noises. In the Present paper we proposed a method for detection and classification of the PKU affected EMG signal. Here Discrete Wavelet Transformation is implemented for extraction of the features of the PKU affected EMG signal. Adaptive Neuro-Fuzzy Inference System (ANFIS) network is used for the classification of the signal. Modified Particle Swarm Optimization (MPSO) and Modified Genetic Algorithm (MGA) are used to train the ANFIS network. Simulation result shows that the proposed method gives better performance as compared to existing approaches. Also it gives better accuracy of 98.02% for the detection of PKU-EMG signal. The advantages of the proposed model is to use MGA and MPSO to train the parameters of ANFIS network for classification of ECG and EMG signal of PKU affected patients. The proposed method obtained the high SNR (18.13 ± 0.36 dB), SNR (0.52 ± 1.62 dB), RE (0.02 ± 0.32), MSE (0.64 ± 2.01), CC (0.99 ± 0.02), RMSE (0.75 ± 0.35) and MFRE (0.01 ± 0.02), RMSE (0.75 ± 0.35) and MFRE (0.01 ± 0.02). From authors knowledge, this is the first time a composite method is used for diagnosis of PKU affected patients. The accuracy (98.02%), sensitivity (100%) and specificity (98.59%) helps for proper clinical treatment. It can help for readers

  19. Nuclear fusion as new energy option in a global single-regional energy system model

    International Nuclear Information System (INIS)

    Eherer, C.; Baumann, M.; Dueweke, J.; Hamacher, T.

    2005-01-01

    Is there a window of opportunity for fusion on the electricity market under 'business as usual' conditions, and if not, how do the boundary conditions have to look like to open such a window? This question is addressed within a subtask of the Socio-Economic Research on Fusion (SERF) programme of the European Commission. The most advanced energy-modelling framework, the TIMES model generator developed by the Energy Technology System Analysis Project group of the IEA (ETSAP) has been used to implement a global single-regional partial equilibrium energy model. Within the current activities the potential role of fusion power in various future energy scenarios is studied. The final energy demand projections of the baseline of the investigations are based on IIASA-WEC Scenario B. Under the quite conservative baseline assumptions fusion only enters the model solution with 35 GW in 2100 and it can be observed that coal technologies dominate electricity production in 2100. Scenario variations show that the role of fusion power is strongly affected by the availability of GEN IV fission breeding technologies as energy option and by CO 2 emission caps. The former appear to be a major competitor of fusion power while the latter open a window of opportunity for fusion power on the electricity market. An interesting outcome is furthermore that the possible share of fusion electricity is more sensitive to the potential of primary resources like coal, gas and uranium, than to the share of solar and wind power in the system. This indicates that both kinds of technologies, renewables and fusion power, can coexist in future energy systems in case of CO 2 emission policies and/or resource scarcity scenarios. It is shown that Endogenous Technological Learning (ETL), a more consistent description of technological progress than mere time series, has an impact on the model results. (author)

  20. Simple transmission Raman measurements using a single multivariate model for analysis of pharmaceutical samples contained in capsules of different colors.

    Science.gov (United States)

    Lee, Yeojin; Kim, Jaejin; Lee, Sanguk; Woo, Young-Ah; Chung, Hoeil

    2012-01-30

    Direct transmission Raman measurements for analysis of pharmaceuticals in capsules are advantageous since they can be used to determine active pharmaceutical ingredient (API) concentrations in a non-destructive manner and with much less fluorescence background interference from the capsules themselves compared to conventional back-scattering measurements. If a single calibration model such as developed from spectra simply collected in glass vials could be used to determine API concentrations of samples contained in capsules of different colors rather than constructing individual models for each capsule color, the utility of transmission measurements would be further enhanced. To evaluate the feasibility, transmission Raman spectra of binary mixtures of ambroxol and lactose were collected in a glass vial and a partial least squares (PLS) model for the determination of ambroxol concentration was developed. Then, the model was directly applied to determine ambroxol concentrations of samples contained in capsules of 4 different colors (blue, green, white and yellow). Although the prediction performance was slightly degraded when the samples were placed in blue or green capsules, due to the presence of weak fluorescence, accurate determination of ambroxol was generally achieved in all cases. The prediction accuracy was also investigated when the thickness of the capsule was varied. Copyright © 2011 Elsevier B.V. All rights reserved.

  1. Concentrated Solutions of Single-Chain Nanoparticles: A Simple Model for Intrinsically Disordered Proteins under Crowding Conditions.

    Science.gov (United States)

    Moreno, Angel J; Lo Verso, Federica; Arbe, Arantxa; Pomposo, José A; Colmenero, Juan

    2016-03-03

    By means of large-scale computer simulations and small-angle neutron scattering (SANS), we investigate solutions of single-chain nanoparticles (SCNPs), covering the whole concentration range from infinite dilution to melt density. The analysis of the conformational properties of the SCNPs reveals that these synthetic nano-objects share basic ingredients with intrinsically disordered proteins (IDPs), as topological polydispersity, generally sparse conformations, and locally compact domains. We investigate the role of the architecture of the SCNPs in their collapse behavior under macromolecular crowding. Unlike in the case of linear macromolecules, which experience the usual transition from self-avoiding to Gaussian random-walk conformations, crowding leads to collapsed conformations of SCNPs resembling those of crumpled globules. This behavior is already found at volume fractions (about 30%) that are characteristic of crowding in cellular environments. The simulation results are confirmed by the SANS experiments. Our results for SCNPs--a model system free of specific interactions--propose a general scenario for the effect of steric crowding on IDPs: collapse from sparse conformations at high dilution to crumpled globular conformations in cell environments.

  2. The "Parachute" Technique: A Simple and Effective Single-Row Procedure to Achieve an Increased Contact Area Between the Cuff-Tendon and Its Footprint.

    Science.gov (United States)

    Natera, Luis; Consigliere, Paolo; Witney-Lagen, Caroline; Brugera, Juan; Sforza, Giuseppe; Atoun, Ehud; Levy, Ofer

    2017-10-01

    Many techniques of arthroscopic rotator cuff repair have been described. No significant differences in clinical outcomes or rerupture rates have been observed when comparing single-row with double-row methods. Not all single- and double-row repairs are the same. The details of the technique used are crucial. It has been shown that the suture-tendon interface is the weakest point of the reconstruction. Therefore, the biomechanical properties of rotator cuff repairs might be influenced more by the suture configuration than by the number of anchors or by the number of rows involved. Techniques that secure less amount of tendon over a smaller area of the healing zone might be expected to have higher failure rates. The way the sutures of the "parachute technique" are configured represents a quadruple mattress that increases the contact and pressure between the tendon and its footprint and increases the primary load to failure of the repair. We present a simple and effective single-row technique that involves the biomechanical and biological advantages related to the increased contact area and pressure between the cuff and its footprint.

  3. A retrospective study comparing the outcome of horses undergoing small intestinal resection and anastomosis with a single layer (Lembert) or double layer (simple continuous and Cushing) technique.

    Science.gov (United States)

    Close, Kristyn; Epstein, Kira L; Sherlock, Ceri E

    2014-05-01

    To (1) compare postoperative complications and survival in horses after small intestinal resection and anastomosis using 2 anastomosis techniques (single layer Lembert; double layer simple continuous oversewn with Cushing), and (2) to compare outcome by anastomosis type (jejunoileostomy; jejunojejunostomy). Retrospective case series. Horses (n = 53). Medical records (July 2006-July 2010) of all horses that had small intestinal resection and anastomosis. Horses were divided into groups based on technique and type of anastomosis. Comparisons of pre- and intraoperative findings (disease severity), postoperative complications, and survival rates were made between groups. There were no differences in disease severity, postoperative complications, or survival between single layer (n = 23) or double layer (n = 31) anastomoses. There were no differences in disease severity or survival between jejunoileostomy (n = 16) or jejunojejunostomy (n = 38). There was a higher incidence of postoperative colic in hospital after jejunoileostomy (13/16) compared with jejunojejunostomy (18/38) (P = .0127). Postoperative complications and survival are comparable between horses undergoing single layer and double layer small intestinal end-to-end anastomoses. With the exception of increased postoperative colic in the hospital, postoperative complications and survival after jejunoileostomy and jejunojejunostomy are also comparable. © Copyright 2014 by The American College of Veterinary Surgeons.

  4. A single bout of meditation biases cognitive control but not attentional focusing: Evidence from the global-local task.

    Science.gov (United States)

    Colzato, Lorenza S; van der Wel, Pauline; Sellaro, Roberta; Hommel, Bernhard

    2016-01-01

    Recent studies show that a single bout of meditation can impact information processing. We were interested to see whether this impact extends to attentional focusing and the top-down control over irrelevant information. Healthy adults underwent brief single bouts of either focused attention meditation (FAM), which is assumed to increase top-down control, or open monitoring meditation (OMM), which is assumed to weaken top-down control, before performing a global-local task. While the size of the global-precedence effect (reflecting attentional focusing) was unaffected by type of meditation, the congruency effect (indicating the failure to suppress task-irrelevant information) was considerably larger after OMM than after FAM. Our findings suggest that engaging in particular kinds of meditation creates particular cognitive-control states that bias the individual processing style toward either goal-persistence or cognitive flexibility. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Using a medium-throughput comet assay to evaluate the global DNA methylation status of single cells

    Science.gov (United States)

    Lewies, Angélique; Van Dyk, Etresia; Wentzel, Johannes F.; Pretorius, Pieter J.

    2014-01-01

    The comet assay is a simple and cost effective technique, commonly used to analyze and quantify DNA damage in individual cells. The versatility of the comet assay allows introduction of various modifications to the basic technique. The difference in the methylation sensitivity of the isoschizomeric restriction enzymes HpaII and MspI are used to demonstrate the ability of the comet assay to measure the global DNA methylation level of individual cells when using cell cultures. In the experiments described here, a medium-throughput comet assay and methylation sensitive comet assay are combined to produce a methylation sensitive medium-throughput comet assay to measure changes in the global DNA methylation pattern in individual cells under various growth conditions. PMID:25071840

  6. Globalization

    DEFF Research Database (Denmark)

    Plum, Maja

    Globalization is often referred to as external to education - a state of affair facing the modern curriculum with numerous challenges. In this paper it is examined as internal to curriculum; analysed as a problematization in a Foucaultian sense. That is, as a complex of attentions, worries, ways...... of reasoning, producing curricular variables. The analysis is made through an example of early childhood curriculum in Danish Pre-school, and the way the curricular variable of the pre-school child comes into being through globalization as a problematization, carried forth by the comparative practices of PISA...

  7. Globalization

    OpenAIRE

    F. Gerard Adams

    2008-01-01

    The rapid globalization of the world economy is causing fundamental changes in patterns of trade and finance. Some economists have argued that globalization has arrived and that the world is “flat†. While the geographic scope of markets has increased, the author argues that new patterns of trade and finance are a result of the discrepancies between “old†countries and “new†. As the differences are gradually wiped out, particularly if knowledge and technology spread worldwide, the t...

  8. Rudimentary simple, single step fabrication of nano-flakes like AgCd alloy electro-catalyst for oxygen reduction reaction in alkaline fuel cell

    International Nuclear Information System (INIS)

    Bhandary, Nimai; Basu, Suddhasatwa; Ingole, Pravin P.

    2016-01-01

    In this work, for the first time, we report rudimentary simple, single step fabrication of an electro-catalyst based on AgCd alloy nanoparticles with flakes like geometry which shows highly efficient activity towards oxygen reduction reaction (ORR). A simple potentiostatic deposition method has been employed for co-depositing AgCd alloy nanostructures with flakes like shapes along with dendrites on the surface of carbon fibre paper. The chemico-physical properties of the catalyst are investigated by X-ray diffraction (XRD), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and energy dispersive X-ray spectroscopy (EDXS). Electro-catalytic activity of AgCd alloy based electro-catalyst towards ORR is studied in alkaline medium by cyclic voltammetry and rotating ring disk electrode (RRDE) technique. Electrochemical in-situ FTIR measurements are also performed to identify the species generated during ORR process. Based on the results from electro-catalysis experiment, it is concluded that nano-alloyed AgCd electrodeposited on carbon paper shows excellent activity for ORR, following four electron pathways with H_2O_2 yield less than 15%. The combination of low cost of Ag and Cd, fast and facile method of its fabrication and higher activity towards ORR makes the AgCd electro-catalyst an attractive catalyst of choice for alkaline fuel cell.

  9. Global-Local Finite Element Analysis of Bonded Single-Lap Joints

    Science.gov (United States)

    Kilic, Bahattin; Madenci, Erdogan; Ambur, Damodar R.

    2004-01-01

    Adhesively bonded lap joints involve dissimilar material junctions and sharp changes in geometry, possibly leading to premature failure. Although the finite element method is well suited to model the bonded lap joints, traditional finite elements are incapable of correctly resolving the stress state at junctions of dissimilar materials because of the unbounded nature of the stresses. In order to facilitate the use of bonded lap joints in future structures, this study presents a finite element technique utilizing a global (special) element coupled with traditional elements. The global element includes the singular behavior at the junction of dissimilar materials with or without traction-free surfaces.

  10. Potencial de híbridos simples de milho para extração de linhagens Potential of maize single hybrids to generate inbred lines

    Directory of Open Access Journals (Sweden)

    Odair Bison

    2003-04-01

    Full Text Available A utilização de híbridos simples comerciais de milho é uma das opções de populações para a extração de linhagens, porque são adaptados e provavelmente concentram alta freqüência de alelos favoráveis já fixados. Mesmo nos locos que estão segregando, a freqüência de alelos favoráveis é 0,5. Assim, a identificação de populações promissoras, derivadas de híbridos simples superiores, é uma boa estratégia para aumentar a eficiência dos programas de melhoramento. As populações derivadas dos híbridos simples comerciais AG9012 e C333 foram avaliadas com o objetivo de verificar o potencial dessas para extração de linhagens superiores, por meio das estimativas de parâmetros genéticos e fenotípicos, da estimativa de m+a e a metodologia proposta por Jinks & Pooni (1976. Foram avaliadas 169 famílias S1 de cada população, durante a safra agrícola de 1999/2000, na área experimental do Departamento de Biologia da UFLA, em Lavras - MG, em látice simples 13x13, sendo as parcelas constituídas por uma linha de 3 m. As características analisadas foram incidência de Phaeosphaeria maydis em duas épocas, altura de plantas, altura de espigas e produtividade de espigas despalhadas. Foi constatado que há possibilidade de se obterem linhagens com bom desempenho per se, sendo a população derivada do C333 a mais promissora, por associar resistência a Phaeosphaeria maydis e possuir média mais alta e maior probabilidade de obtenção de linhagens superiores. A metodologia proposta por Jinks & Pooni (1976 mostrou-se mais informativa do que a estimativa de m+a para a escolha de populações, mas, quando possível, as duas podem ser utilizadas simultaneamente para auxiliar na decisão dos melhoristas.Populations derived from commercial single hybrids are one of the breeder options for inbred line extraction because of their adaptation and probable high frequency of loci with fixed favorable alleles. Even the segregating loci carry

  11. Solute transport along a single fracture in a porous rock: a simple analytical solution and its extension for modeling velocity dispersion

    Science.gov (United States)

    Liu, Longcheng; Neretnieks, Ivars; Shahkarami, Pirouz; Meng, Shuo; Moreno, Luis

    2018-02-01

    A simple and robust solution is developed for the problem of solute transport along a single fracture in a porous rock. The solution is referred to as the solution to the single-flow-path model and takes the form of a convolution of two functions. The first function is the probability density function of residence-time distribution of a conservative solute in the fracture-only system as if the rock matrix is impermeable. The second function is the response of the fracture-matrix system to the input source when Fickian-type dispersion is completely neglected; thus, the effects of Fickian-type dispersion and matrix diffusion have been decoupled. It is also found that the solution can be understood in a way in line with the concept of velocity dispersion in fractured rocks. The solution is therefore extended into more general cases to also account for velocity variation between the channels. This leads to a development of the multi-channel model followed by detailed statistical descriptions of channel properties and sensitivity analysis of the model upon changes in the model key parameters. The simulation results obtained by the multi-channel model in this study fairly well agree with what is often observed in field experiments—i.e. the unchanged Peclet number with distance, which cannot be predicted by the classical advection-dispersion equation. In light of the findings from the aforementioned analysis, it is suggested that forced-gradient experiments can result in considerably different estimates of dispersivity compared to what can be found in natural-gradient systems for typical channel widths.

  12. Verification of RELAP5/MOD3 with theoretical and numerical stability results on single-phase, natural circulation in a simple loop

    International Nuclear Information System (INIS)

    Ferreri, Juan C.; Ambrosini, Walter

    1998-01-01

    The theoretical results given by Pierre Welander are used to test the capability of the RELAP5 series of codes to predict instabilities in single-phase flow. These results are related to the natural circulation in a loop formed by two parallel adiabatic tubes with a point heat sink at the top and a point heat source at the bottom. A stability curve may be defined for laminar flow and was extended to consider turbulent flow. By a suitable selection of the ratio of the total buoyancy force in the loop to the friction resistance, the flow may show instabilities. The solution was useful to test two basic numerical properties of the RELAP5 code, namely: a) convergence to steady state flow-rate using a 'lumped parameter' approximation to both the heat source and sink and; b) the effect of nodalization to numerically damp the instabilities. It was shown that, using a single volume to lump the heat source and sink, it was not possible to reach convergence to steady state flow rate when the heated (cooled) length was diminished and the heat transfer coefficient increased to keep constant the total heat transferred to (and removed from) the fluid. An algebraic justification of these results is presented, showing that it is a limitation inherent to the numerical scheme adopted. Concerning the effect of nodalization on the damping of instabilities, it was shown that a 'reasonably fine' discretization led, as expected, to the damping of the solution. However, the search for convergence of numerical and theoretical results was successful, showing the expected nearly chaotic behavior. This search lead to very refined nodalization. The results obtained have also been verified by the use of simple, ad hoc codes. A procedure to assess the effects of nodalization on the prediction of instabilities threshold is outlined in this report. It is based on the experience gained with aforementioned simpler codes. (author)

  13. IMPACT OF GLOBAL WARMING ON LIFE: LIFE ON EARTH FROM SINGLE-CELLULAR ORGANISMS TO MULTICELLULAR ORGANISMS

    Energy Technology Data Exchange (ETDEWEB)

    Kartikey Gupta [Grade X, Mayura School, Jaipur (India)

    2008-09-30

    Wherever we look, life can be seen...so many different forms of life, that is, uncountable varieties of animals and plants occupy the whole world today! But, where and how did it all start? The story of evolution is one of the most interesting theories ever put forward. It refers to - the way that simple and small living things eventually changed into much more functional and bigger beings, in course of time. Charles Darwin had explored this mystery, and had provided the reason- Evolution. Evolution is changing of life forms into more functional ones with respect to their changing environment. However, as odd as it may sound, evolution and extinction are closely linked. Because, the better evolved species survives, and throughout the timeline of evolution, there have been many extinction waves. They were all occurred naturally thus proving that the very process of extinction is natural. The earth has seen many variations of global temperature; it has suffered various ice ages, which had also many a times threatened to eradicate most life from the planet. But, every time life has found a way to go on. Therefore, whatever life we see today has resulted from the ongoing long process of evolution. After millions of years, finally we humans have come into existence, and today are the leading species of the world. But, we may possibly be very close to another major extinction wave, the root causes of which are both natural and man-made, but the part played by the latter is much more than the former. Global Warming has now started affecting all kinds of life on the planet, and it is our responsibility as the leading and most intellectual species to try to save our earth. A study reveals that 60% Indian people do not actually know about Global Warming, and that the number of youth aware of Global Warming and Its impacts are much more than the number of adults. About 75% Indians believe that it is the sole responsibility of the government to solve the problems related to

  14. Ambiguity resolution in precise point positioning with hourly data for global single receiver

    Science.gov (United States)

    Zhang, Xiaohong; Li, Pan; Guo, Fei

    2013-01-01

    Integer ambiguity resolution (IAR) can improve precise point positioning (PPP) performance significantly. IAR for PPP became a highlight topic in global positioning system (GPS) community in recent years. More and more researchers focus on this issue. Progress has been made in the latest years. In this paper, we aim at investigating and demonstrating the performance of a global zero-differenced (ZD) PPP IAR service for GPS users by providing routine ZD uncalibrated fractional offsets (UFOs) for wide-lane and narrow-lane. Data sets from all IGS stations collected on DOY 1, 100, 200 and 300 of 2010 are used to validate and demonstrate this global service. Static experiment results show that an accuracy better than 1 cm in horizontal and 1-2 cm in vertical could be achieved in ambiguity-fixed PPP solution with only hourly data. Compared with PPP float solution, an average improvement reaches 58.2% in east, 28.3% in north and 23.8% in vertical for all tested stations. Results of kinematic experiments show that the RMS of kinematic PPP solutions can be improved from 21.6, 16.6 and 37.7 mm to 12.2, 13.3 and 34.3 mm for the fixed solutions in the east, north and vertical components, respectively. Both static and kinematic experiments show that wide-lane and narrow-lane UFO products of all satellites can be generated and provided in a routine way accompanying satellite orbit and clock products for the PPP user anywhere around the world, to obtain accurate and reliable ambiguity-fixed PPP solutions.

  15. Type I error rates of rare single nucleotide variants are inflated in tests of association with non-normally distributed traits using simple linear regression methods.

    Science.gov (United States)

    Schwantes-An, Tae-Hwi; Sung, Heejong; Sabourin, Jeremy A; Justice, Cristina M; Sorant, Alexa J M; Wilson, Alexander F

    2016-01-01

    In this study, the effects of (a) the minor allele frequency of the single nucleotide variant (SNV), (b) the degree of departure from normality of the trait, and (c) the position of the SNVs on type I error rates were investigated in the Genetic Analysis Workshop (GAW) 19 whole exome sequence data. To test the distribution of the type I error rate, 5 simulated traits were considered: standard normal and gamma distributed traits; 2 transformed versions of the gamma trait (log 10 and rank-based inverse normal transformations); and trait Q1 provided by GAW 19. Each trait was tested with 313,340 SNVs. Tests of association were performed with simple linear regression and average type I error rates were determined for minor allele frequency classes. Rare SNVs (minor allele frequency < 0.05) showed inflated type I error rates for non-normally distributed traits that increased as the minor allele frequency decreased. The inflation of average type I error rates increased as the significance threshold decreased. Normally distributed traits did not show inflated type I error rates with respect to the minor allele frequency for rare SNVs. There was no consistent effect of transformation on the uniformity of the distribution of the location of SNVs with a type I error.

  16. Ecological significance of compatible solute accumulation by micro-organisms: from single cells to global climate.

    Science.gov (United States)

    Welsh, D T

    2000-07-01

    The osmoadaptation of most micro-organisms involves the accumulation of K(+) ions and one or more of a restricted range of low molecular mass organic solutes, collectively termed 'compatible solutes'. These solutes are accumulated to high intracellular concentrations, in order to balance the osmotic pressure of the growth medium and maintain cell turgor pressure, which provides the driving force for cell extension growth. In this review, I discuss the alternative roles which compatible solutes may also play as intracellular reserves of carbon, energy and nitrogen, and as more general stress metabolites involved in protection of cells against other environmental stresses including heat, desiccation and freezing. Thus, the evolutionary selection for the accumulation of a specific compatible solute may not depend solely upon its function during osmoadaptation, but also upon the secondary benefits its accumulation provides, such as increased tolerance of other environmental stresses prevalent in the organism's niche or even anti-herbivory or dispersal functions in the case of dimethylsulfoniopropionate (DMSP). In the second part of the review, I discuss the ecological consequences of the release of compatible solutes to the environment, where they can provide sources of compatible solutes, carbon, nitrogen and energy for other members of the micro-flora. Finally, at the global scale the metabolism of specific compatible solutes (betaines and DMSP) in brackish water, marine and hypersaline environments may influence global climate, due to the production of the trace gases, methane and dimethylsulfide (DMS) and in the case of DMS, also couple the marine and terrestrial sulfur cycles.

  17. Dependence of stratocumulus-topped boundary-layer entrainment on cloud-water sedimentation: Impact on global aerosol indirect effect in GISS ModelE3 single column model and global simulations

    Science.gov (United States)

    Ackerman, A. S.; Kelley, M.; Cheng, Y.; Fridlind, A. M.; Del Genio, A. D.; Bauer, S.

    2017-12-01

    Reduction in cloud-water sedimentation induced by increasing droplet concentrations has been shown in large-eddy simulations (LES) and direct numerical simulation (DNS) to enhance boundary-layer entrainment, thereby reducing cloud liquid water path and offsetting the Twomey effect when the overlying air is sufficiently dry, which is typical. Among recent upgrades to ModelE3, the latest version of the NASA Goddard Institute for Space Studies (GISS) general circulation model (GCM), are a two-moment stratiform cloud microphysics treatment with prognostic precipitation and a moist turbulence scheme that includes an option in its entrainment closure of a simple parameterization for the effect of cloud-water sedimentation. Single column model (SCM) simulations are compared to LES results for a stratocumulus case study and show that invoking the sedimentation-entrainment parameterization option indeed reduces the dependence of cloud liquid water path on increasing aerosol concentrations. Impacts of variations of the SCM configuration and the sedimentation-entrainment parameterization will be explored. Its impact on global aerosol indirect forcing in the framework of idealized atmospheric GCM simulations will also be assessed.

  18. Simple machines

    CERN Document Server

    Graybill, George

    2007-01-01

    Just how simple are simple machines? With our ready-to-use resource, they are simple to teach and easy to learn! Chocked full of information and activities, we begin with a look at force, motion and work, and examples of simple machines in daily life are given. With this background, we move on to different kinds of simple machines including: Levers, Inclined Planes, Wedges, Screws, Pulleys, and Wheels and Axles. An exploration of some compound machines follows, such as the can opener. Our resource is a real time-saver as all the reading passages, student activities are provided. Presented in s

  19. Yielding the yield-stress analysis: a study focused on the effects of elasticity on the settling of a single spherical particle in simple yield-stress fluids.

    Science.gov (United States)

    Fraggedakis, D; Dimakopoulos, Y; Tsamopoulos, J

    2016-06-28

    The sedimentation of a single particle in materials that exhibit simultaneously elastic, viscous and plastic behavior is examined in an effort to explain phenomena that contradict the nature of purely yield-stress materials. Such phenomena include the loss of the fore-and-aft symmetry with respect to an isolated settling particle under creeping flow conditions and the appearance of the "negative wake" behind it. Despite the fact that similar observations have been reported in studies involving viscoelastic fluids, researchers conjectured that thixotropy is responsible for these phenomena, as the aging of yield-stress materials is another common feature. By means of transient calculations, we study the effect of elasticity on both the fluidized and the solid phase. The latter is considered to behave as an ideal Hookean solid. The material properties of the model are determined under the isotropic kinematic hardening framework via Large Amplitude Oscillatory Shear (LAOS) measurements. In this way, we are able to predict accurately the unusual phenomena observed in experiments with simple yield-stress materials, irrespective of the appearance of slip on the particle surface. Viscoelasticity favors the formation of intense shear and extensional stresses downstream of the particle, significantly changing the entrapment mechanism in comparison to that observed in viscoplastic fluids. Therefore, the critical conditions under which the entrapment of the particle occurs deviate from the well-known criterion established theoretically by Beris et al. (1985) and verified experimentally by Tabuteau et al. (2007) for similar materials under conditions that elastic effects are negligible. Our predictions are in quantitative agreement with published experimental results by Holenberg et al. (2012) on the loss of the fore-aft symmetry and the formation of the negative wake in Carbopol with well-characterized rheology. Additionally, we propose simple expressions for the Stokes drag

  20. Variational contrast enhancement guided by global and local contrast measurements for single-image defogging

    Science.gov (United States)

    Zhou, Li; Bi, Du-Yan; He, Lin-Yuan

    2015-01-01

    The visibility of images captured in foggy conditions is impaired severely by a decrease in the contrasts of objects and veiling with a characteristic gray hue, which may limit the performance of visual applications out of doors. Contrast enhancement together with color restoration is a challenging mission for conventional fog-removal methods, as the degrading effect of fog is largely dependent on scene depth information. Nowadays, people change their minds by establishing a variational framework for contrast enhancement based on a physically based analytical model, unexpectedly resulting in color distortion, dark-patch distortion, or fuzzy features of local regions. Unlike previous work, our method treats an atmospheric veil as a scattering disturbance and formulates a foggy image as an energy functional minimization to estimate direct attenuation, originating from the work of image denoising. In addition to a global contrast measurement based on a total variation norm, an additional local measurement is designed in that optimal problem for the purpose of digging out more local details as well as suppressing dark-patch distortion. Moreover, we estimate the airlight precisely by maximization with a geometric constraint and a natural image prior in order to protect the faithfulness of the scene color. With the estimated direct attenuation and airlight, the fog-free image can be restored. Finally, our method is tested on several benchmark and realistic images evaluated by two assessment approaches. The experimental results imply that our proposed method works well compared with the state-of-the-art defogging methods.

  1. Dimensions and Global Twist of Single-Layer DNA Origami Measured by Small-Angle X-ray Scattering.

    Science.gov (United States)

    Baker, Matthew A B; Tuckwell, Andrew J; Berengut, Jonathan F; Bath, Jonathan; Benn, Florence; Duff, Anthony P; Whitten, Andrew E; Dunn, Katherine E; Hynson, Robert M; Turberfield, Andrew J; Lee, Lawrence K

    2018-06-04

    The rational design of complementary DNA sequences can be used to create nanostructures that self-assemble with nanometer precision. DNA nanostructures have been imaged by atomic force microscopy and electron microscopy. Small-angle X-ray scattering (SAXS) provides complementary structural information on the ensemble-averaged state of DNA nanostructures in solution. Here we demonstrate that SAXS can distinguish between different single-layer DNA origami tiles that look identical when immobilized on a mica surface and imaged with atomic force microscopy. We use SAXS to quantify the magnitude of global twist of DNA origami tiles with different crossover periodicities: these measurements highlight the extreme structural sensitivity of single-layer origami to the location of strand crossovers. We also use SAXS to quantify the distance between pairs of gold nanoparticles tethered to specific locations on a DNA origami tile and use this method to measure the overall dimensions and geometry of the DNA nanostructure in solution. Finally, we use indirect Fourier methods, which have long been used for the interpretation of SAXS data from biomolecules, to measure the distance between DNA helix pairs in a DNA origami nanotube. Together, these results provide important methodological advances in the use of SAXS to analyze DNA nanostructures in solution and insights into the structures of single-layer DNA origami.

  2. Simple prostatectomy

    Science.gov (United States)

    ... Han M, Partin AW. Simple prostatectomy: open and robot-assisted laparoscopic approaches. In: Wein AJ, Kavoussi LR, ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  3. Global and local characteristics of an autogenous single pass electron beam weld in thick gage UNS S41500 steel

    Energy Technology Data Exchange (ETDEWEB)

    Sarafan, S., E-mail: Sheida.Sarafan.1@ens.etsmtl.ca [École de Technologie Supérieure, Montréal, Québec, Canada H3C 1K3 (Canada); National Research Council Canada, Aerospace, Montréal, Québec, Canada H3T 2B2 (Canada); Wanjara, P., E-mail: priti.wanjara@nrc-cnrc.gc.ca [National Research Council Canada, Aerospace, Montréal, Québec, Canada H3T 2B2 (Canada); Gholipour, J., E-mail: Javad.gholipour@nrc-cnrc.gc.ca [National Research Council Canada, Aerospace, Montréal, Québec, Canada H3T 2B2 (Canada); Champliaud, H., E-mail: henri.champliaud@etsmtl.ca [École de Technologie Supérieure, Montréal, Québec, Canada H3C 1K3 (Canada)

    2016-06-01

    Electron beam welding of UNS S41500, a low carbon martensitic stainless steel utilized in hydroelectric turbine manufacturing, was investigated by applying a single pass autogenous process to penetrate a section thickness of 72 mm without preheating. In the as-welded and post-weld heat treated conditions, the evolution in microhardness and microstructure across the weldments, as well as the global and local tensile properties, were evaluated. In the as-welded condition, assessment of the microhardness and the associated microstructure across the welds led to the identification of six regions, including the fusion zone, four heat affected zones and the base metal; each of these regions consisted of different phase constituents, such as tempered martensite, untempered martensite, delta ferrite and retained austenite. Post-weld heat treatment, undertaken to temper the untempered martensite in the as-welded microstructure, was effective in homogenizing the hardness across the weldment. The mechanical response of the welds, determined through tensile testing at room temperature with an automated non-contact three-dimensional deformation measurement system, indicated that the global tensile properties in the as-welded and post-weld heat treated conditions met the acceptance criteria in the ASME Section IX standard. Also, evaluation of the local tensile properties in the fusion and heat affected zones of the as-welded samples allowed a more comprehensive understanding of the strength and ductility associated with the different microstructures in the “composite” nature of the weldment. Fractographic analysis demonstrated dimpled features on the tensile fracture surfaces and failure was associated with debonding between the martensitic matrix and the secondary phases (such as delta ferrite and retained austenite) that resulted in the formation, growth and coalescence of voids into a macroscale crack.

  4. It Is Not That Simple nor Compelling!; Comment on “Translating Evidence Into Healthcare Policy and Practice: Single Versus Multi-faceted Implementation Strategies – Is There a Simple Answer to a Complex Question?”

    Directory of Open Access Journals (Sweden)

    Tracey Bucknall

    2015-11-01

    Full Text Available Healthcare decisions are often made under pressure, with varying levels of information in a changing clinical context. With limited resources and a focus on improving patient outcomes, healthcare managers and health professionals strive to implement both clinical and cost-effective care. However, the gap between research evidence and health policy/clinical practice persists despite our best efforts. In an attempt to close the gap through behaviour change interventions, there has been a strong held belief that ‘more is better,’ without understanding the mechanisms and circumstances of knowledge translation (KT. We argue that even a singleintervention or strategy in translating evidence into healthcare policy or practice is rarely simple to implement. Nor is the evidence compelling on the best approach. As Harvey and Kitson argued, designing and evaluating KT interventions requires flexibility and responsiveness. If we are to move forward in translation science then we need to use rigorous designs such as randomised controlled trials to test effectiveness of interventions or strategies with embedded process evaluations to understand the reason interventions do or do not work!

  5. Quantitative historical analysis uncovers a single dimension of complexity that structures global variation in human social organization

    Science.gov (United States)

    Turchin, Peter; Currie, Thomas E.; Whitehouse, Harvey; François, Pieter; Feeney, Kevin; Mullins, Daniel; Hoyer, Daniel; Collins, Christina; Grohmann, Stephanie; Mendel-Gleason, Gavin; Turner, Edward; Dupeyron, Agathe; Cioni, Enrico; Reddish, Jenny; Levine, Jill; Jordan, Greine; Brandl, Eva; Williams, Alice; Cesaretti, Rudolf; Krueger, Marta; Ceccarelli, Alessandro; Figliulo-Rosswurm, Joe; Tuan, Po-Ju; Peregrine, Peter; Marciniak, Arkadiusz; Preiser-Kapeller, Johannes; Kradin, Nikolay; Korotayev, Andrey; Palmisano, Alessio; Baker, David; Bidmead, Julye; Bol, Peter; Christian, David; Cook, Connie; Covey, Alan; Feinman, Gary; Júlíusson, Árni Daníel; Kristinsson, Axel; Miksic, John; Mostern, Ruth; Petrie, Cameron; Rudiak-Gould, Peter; ter Haar, Barend; Wallace, Vesna; Mair, Victor; Xie, Liye; Baines, John; Bridges, Elizabeth; Manning, Joseph; Lockhart, Bruce; Bogaard, Amy; Spencer, Charles

    2018-01-01

    Do human societies from around the world exhibit similarities in the way that they are structured, and show commonalities in the ways that they have evolved? These are long-standing questions that have proven difficult to answer. To test between competing hypotheses, we constructed a massive repository of historical and archaeological information known as “Seshat: Global History Databank.” We systematically coded data on 414 societies from 30 regions around the world spanning the last 10,000 years. We were able to capture information on 51 variables reflecting nine characteristics of human societies, such as social scale, economy, features of governance, and information systems. Our analyses revealed that these different characteristics show strong relationships with each other and that a single principal component captures around three-quarters of the observed variation. Furthermore, we found that different characteristics of social complexity are highly predictable across different world regions. These results suggest that key aspects of social organization are functionally related and do indeed coevolve in predictable ways. Our findings highlight the power of the sciences and humanities working together to rigorously test hypotheses about general rules that may have shaped human history. PMID:29269395

  6. Droids Made Simple

    CERN Document Server

    Mazo, Gary

    2011-01-01

    If you have a Droid series smartphone - Droid, Droid X, Droid 2, or Droid 2 Global - and are eager to get the most out of your device, Droids Made Simple is perfect for you. Authors Martin Trautschold, Gary Mazo and Marziah Karch guide you through all of the features, tips, and tricks using their proven combination of clear instructions and detailed visuals. With hundreds of annotated screenshots and step-by-step directions, Droids Made Simple will transform you into a Droid expert, improving your productivity, and most importantly, helping you take advantage of all of the cool features that c

  7. Analyser for fast single events; Analyseur d'evenements rapides simples; Analizator bystrykh odnokratnykh yavlenij; Analizador de sucesos rapidos no recurrentes

    Energy Technology Data Exchange (ETDEWEB)

    Sedlmeyer, J W; Patten, R B; Fussell, L Jr [Edgerton, Germeshausen And Grier, Inc., Las Vegas, NV (United States)

    1962-04-15

    An electronic analyser has been designed and constructed for use with single non-recurring transient signals. The signal, during passage along a coaxial line, is sampled instantaneously at a number of tap-off points, by means of a single short-duration gate pulse. Multipoint time-dissection is accomplished using a gate-duration and a time-interval between samples, which are independently adjustable from about 4 ns. The time-intervals may be programmed in non-linear array, and jitter is less than 0.5 ns. The speed of response is at present limited by diode characteristics. Each sampled voltage is stretched in a circuit which retains the voltage amplitude. A time-stretch by a factor of 10{sup 8} has been realized, with good stability. These data points may be commutated and transmitted over open-wire to low-frequency recording systems ; they may be converted to digital form for rapid data-processing, using conventional equipment; and/or they may be presented visually. The analyser is advantageous, compared with high-speed oscilloscopy, when large numbers of single-transients require individual analysis; such requirements exist for investigations into fluctuations in the response of systems, or for production-testing of components. The analyser is advantageous when the data-analysis must be accomplished quickly after the signal event occurs; it is not necessary to develop films or to read them. The analyser is also advantageous when the analysis-computation centre is located remotely from the event. Applications of this technique in the nuclear field are many. Fluctuation studies of reactors and subcritical assemblies may be carried out rapidly by pulsed neutron techniques. The build-up and decay characteristics of detectors may be determined, together with analysis of statistics and fluctuations. The pulse shape of the radiation wave from nuclear accelerators may be measured. Neutron-spectrometry using the time-of-flight method may be facilitated. Isomeric studies

  8. A global single-sensor analysis of 2002-2011 tropospheric nitrogen dioxide trends observed from space

    Science.gov (United States)

    Schneider, P.; van der A, R. J.

    2012-08-01

    A global nine-year archive of monthly tropospheric NO2 data acquired by the SCanning Imaging Absorption spectroMeter for Atmospheric CartograpHY (SCIAMACHY) instrument was analyzed with respect to trends between August 2002 and August 2011. In the past, similar studies relied on combining data from multiple sensors; however, the length of the SCIAMACHY data set now for the first time allows utilization of a consistent time series from just a single sensor for mapping NO2 trends at comparatively high horizontal resolution (0.25°). This study provides an updated analysis of global patterns in NO2 trends and finds that previously reported decreases in tropospheric NO2 over Europe and the United States as well as strong increases over China and several megacities in Asia have continued in recent years. Positive trends of up to 4.05 (±0.41) × 1015 molecules cm-2 yr-1 and up to 19.7 (±1.9) % yr-1 were found over China, with the regional mean trend being 7.3 (±3.1) % yr-1. The megacity with the most rapid relative increase was found to be Dhaka in Bangladesh. Subsequently focusing on Europe, the study further analyzes trends by country and finds significantly decreasing trends for seven countries ranging from -3.0 (±1.6) % yr-1 to -4.5 (±2.3) % yr-1. A comparison of the satellite data with station data indicates that the trends derived from both sources show substantial differences on the station scale, i.e., when comparing a station trend directly with the equivalent satellite-derived trend at the same location, but provide quite similar large-scale spatial patterns. Finally, the SCIAMACHY-derived NO2 trends are compared with equivalent trends in NO2concentration computed using the Co-operative Programme for Monitoring and Evaluation of the Long-range Transmission of Air Pollutants in Europe (EMEP) model. The results show that the spatial patterns in trends computed from both data sources mostly agree in Central and Western Europe, whereas substantial differences

  9. A single simple procedure for dewaxing, hydration and heat-induced epitope retrieval (HIER) for immunohistochemistry in formalin fixed paraffin-embedded tissue

    DEFF Research Database (Denmark)

    Paulsen, I M S; Dimke, H; Frische, S

    2015-01-01

    Heat-induced epitope retrieval (HIER) is widely used for immunohistochemistry on formalin fixed paraffin-embedded tissue and includes temperatures well above the melting point of paraffin. We therefore tested whether traditional xylene-based removal of paraffin is required on sections from paraff...... of dewaxing in xylene. In conclusion, the HIER procedure described and tested can be used as a single procedure enabling dewaxing, hydration and epitope retrieval for immunohistochemistry in formalin fixed paraffin-embedded tissue....

  10. Sleep-wake patterns in patients with cirrhosis: all you need to know on a single sheet. A simple sleep questionnaire for clinical use.

    Science.gov (United States)

    Montagnese, Sara; Middleton, Benita; Skene, Debra J; Morgan, Marsha Y

    2009-10-01

    Sleep-wake abnormalities are common in patients with cirrhosis but their evaluation is time consuming and laborious. The aim of this study was to assess the validity of a simple Sleep Timing and Sleep Quality Screening questionnaire (STSQS) against an established sleep quality questionnaire and daily sleep diaries. The study population comprised 87 patients with cirrhosis and 19 healthy volunteers. All participants completed the STSQS (sleep quality score range 1-9) and the Pittsburgh Sleep Quality Index (PSQI; total score range: 0-21; scores >5 identify 'poor' sleepers); a subgroup of 35 patients and 12 healthy volunteers also kept daily sleep diaries for 2 weeks. Patients slept significantly less well than the healthy volunteers (total PSQI score: 8.4+/-4.9 vs. 4.6+/-2.5, p4: sensitivity 75%, specificity 93%; patients: STSQS sleep quality >3: sensitivity 83%, specificity 70%). The STSQS provided estimates of habitual sleep timing variables which did not significantly differ from the average data recorded in the sleep diaries, although more variability was observed in the patients. The STSQS provides acceptable estimates of sleep quality and sleep timing and could be used to identify patients with cirrhosis whose sleep behaviour might require further assessment.

  11. Fototerapia simples versus dupla no tratamento de recém-nascidos a termo com hiperbilirrubinemia não-hemolítica Single vs. double phototherapy in the treatment of full-term newborns with nonhemolytic hyperbilirubinemia

    Directory of Open Access Journals (Sweden)

    Ignacia Silva

    2009-10-01

    Full Text Available OBJETIVO: Comparar a eficácia da fototerapia simples (1 painel versus dupla (2 painéis na redução da hiperbilirrubinemia não-hemolítica em recém-nascidos a termo. MÉTODOS: Os recém-nascidos a termo foram randomizados prospectivamente para receber fototerapia simples ou dupla. Os níveis de bilirrubina foram medidos no momento da internação e em intervalos de 12 horas, assim como em seguimento 48 horas após a alta. RESULTADOS: Trinta e sete pacientes receberam fototerapia simples, e 40, dupla. A redução média dos níveis de bilirrubina nas primeiras 24 horas de tratamento foi maior no grupo que recebeu fototerapia dupla (5,1±2,2 mg/dL versus 4,3±2,1 mg/dL, porém sem significância estatística (p = 0,18. As taxas de readmissão foram similares e nenhum dos grupos apresentou efeitos adversos. CONCLUSÃO: A fototerapia dupla não foi mais eficaz do que a fototerapia simples no tratamento da hiperbilirrubinemia não-hemolítica em recém-nascidos a termo. Entretanto, nossos resultados sugerem que a fototerapia dupla possa ser mais eficaz em recém-nascidos a termo com níveis de bilirrubina mais altos no momento da internação.OBJECTIVES: To compare the effectiveness of single (1 panel vs. double (2 panels phototherapy in reducing nonhemolytic hyperbilirubinemia in term newborns. METHODS: Term newborns with hyperbilirubinemia were prospectively randomized to receive double or single phototherapy. Bilirubin levels were measured at admission and at 12-hour intervals, as well as at a follow-up 48 hours after discharge. RESULTS: Thirty-seven patients received single and 40 double phototherapy. The mean decrease in bilirubin level in the first 24 hours of treatment was greater in the double phototherapy group (5.1±2.2 mg/dL vs. 4.3±2.1 mg/dL, but without statistical significance (p = 0.18. Readmission rates were similar and no adverse effects were found in either group. CONCLUSIONS: Double-surface was not more effective than single

  12. A simple, high-throughput method to detect Plasmodium falciparum single nucleotide polymorphisms in the dihydrofolate reductase, dihydropteroate synthase, and P. falciparum chloroquine resistance transporter genes using polymerase chain reaction- and enzyme-linked immunosorbent

    DEFF Research Database (Denmark)

    Alifrangis, Michael; Enosse, Sonia; Pearce, Richard

    2005-01-01

    Single nucleotide polymorphisms (SNPs) in the Plasmodium falciparum dihydrofolate reductase (dhfr), and dihydropteroate synthetase (dhps), and chloroquine resistance transporter (Pfcrt) genes are used as molecular markers of P. falciparum resistance to sulfadoxine/pyrimethamine and chloroquine....... However, to be a practical tool in the surveillance of drug resistance, simpler methods for high-throughput haplotyping are warranted. Here we describe a quick and simple technique that detects dhfr, dhps, and Pfcrt SNPs using polymerase chain reaction (PCR)- and enzyme-linked immunosorbent assay (ELISA...

  13. SSTO RLVs: More Global Reach? A Study of the Use of Single Stage to Orbit Reusable Launch Vehicles as Airlift Platforms.

    Science.gov (United States)

    1996-11-01

    Orbit ( SSTO ) Reusable Launch Vehicles (RLVs) are currently under cooperative development by NASA, the Air Force, and the aerospace industry in the pursuit...exploit these rapid transit technologies to advance ’Global Reach for America.’ The SSTO RLV is a single stage rocket that will be completely reusable...investigated to assess the projected capabilities and costs of the SSTO system. This paper reviews the proposed capabilities of the SSTO system, discusses

  14. Bentonite clay purification for development of polymeric nan composites using a single screw extruder; Purificacao de argila bentonita para desenvolvimento de nanocomposito polimerico utilizando uma extrusora rosca simples

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    In this work, a bentonite clay rich in montmorillonite was purified and chemical treat to be used in the development of poly (methyl methacrylate) /clay nanocomposites via melting processes. After the clay treatment and purification, a masterbatch with 25% clay and 75% PMMA was produced by solution technique, using acetone as solvent. For produce samples with 2.5% clay, the masterbatch along with pure polymer were added and mixed in single screw extruder with a diameter of 16 mm and W/D 26. X-rays diffractometry (XRD) and X-rays fluorescence (XRF). Tests were performed to evaluate and characterizing the bentonite clay used in the development of this work and differential scanning calorimetry (DSC) tests were performed to evaluate changes in the thermal properties of the nanocomposites produced. (author)

  15. A simple, high throughput method to locate single copy sequences from Bacterial Artificial Chromosome (BAC libraries using High Resolution Melt analysis

    Directory of Open Access Journals (Sweden)

    Caligari Peter DS

    2010-05-01

    Full Text Available Abstract Background The high-throughput anchoring of genetic markers into contigs is required for many ongoing physical mapping projects. Multidimentional BAC pooling strategies for PCR-based screening of large insert libraries is a widely used alternative to high density filter hybridisation of bacterial colonies. To date, concerns over reliability have led most if not all groups engaged in high throughput physical mapping projects to favour BAC DNA isolation prior to amplification by conventional PCR. Results Here, we report the first combined use of Multiplex Tandem PCR (MT-PCR and High Resolution Melt (HRM analysis on bacterial stocks of BAC library superpools as a means of rapidly anchoring markers to BAC colonies and thereby to integrate genetic and physical maps. We exemplify the approach using a BAC library of the model plant Arabidopsis thaliana. Super pools of twenty five 384-well plates and two-dimension matrix pools of the BAC library were prepared for marker screening. The entire procedure only requires around 3 h to anchor one marker. Conclusions A pre-amplification step during MT-PCR allows high multiplexing and increases the sensitivity and reliability of subsequent HRM discrimination. This simple gel-free protocol is more reliable, faster and far less costly than conventional PCR screening. The option to screen in parallel 3 genetic markers in one MT-PCR-HRM reaction using templates from directly pooled bacterial stocks of BAC-containing bacteria further reduces time for anchoring markers in physical maps of species with large genomes.

  16. A single simple procedure for dewaxing, hydration and heat-induced epitope retrieval (HIER for immunohistochemistry in formalin fixed paraffin-embedded tissue

    Directory of Open Access Journals (Sweden)

    I.M.S. Paulsen

    2015-11-01

    Full Text Available Heat-induced epitope retrieval (HIER is widely used for immunohistochemistry on formalin fixed paraffin-embedded tissue and includes temperatures well above the melting point of paraffin. We therefore tested whether traditional xylene-based removal of paraffin is required on sections from paraffin-embedded tissue, when HIER is performed by vigorous boiling in 10 mM Tris/0.5 mM EGTA-buffer (pH=9. Immunohistochemical results using HIER with or without prior dewaxing in xylene were evaluated using 7 primary antibodies targeting proteins located in the cytosol, intracellular vesicles and plasma membrane. No effect of omitting prior dewaxing was observed on staining pattern. Semiquantitative analysis did not show HIER to influence the intensity of labelling consistently. Consequently, quantification of immune labelling intensity using fluorescent secondary antibodies was performed at 5 dilutions of primary antibody with and without prior dewaxing in xylene. No effect of omitting prior dewaxing on signal intensity was detectable indicating similar immunoreactivity in dewaxed and non-dewaxed sections. The intensity of staining the nucleus with the DNA-stain ToPro3 was similarly unaffected by omission of dewaxing in xylene. In conclusion, the HIER procedure described and tested can be used as a single procedure enabling dewaxing, hydration and epitope retrieval for immunohistochemistry in formalin fixed paraffin-embedded tissue.

  17. Numerical investigation on lateral migration and lift force of single bubble in simple shear flow in low viscosity fluid using volume of fluid method

    International Nuclear Information System (INIS)

    Zhongchun, Li; Xiaoming, Song; Shengyao, Jiang; Jiyang, Yu

    2014-01-01

    Highlights: • A VOF simulation of bubble in low viscosity fluid was conducted. • Lift force in different viscosity fluid had different lateral migration characteristics. • Bubble with different size migrated to different direction. • Shear stress triggered the bubble deformation process and the bubble deformation came along with the oscillation behaviors. - Abstract: Two phase flow systems have been widely used in industrial engineering. Phase distribution characteristics are vital to the safety operation and optimization design of two phase flow systems. Lift force has been known as perpendicular to the bubbles’ moving direction, which is one of the mechanisms of interfacial momentum transfer. While most widely used lift force correlations, such as the correlation of Tomiyama et al. (2002), were obtained by experimentally tracking single bubble trajectories in high viscosity glycerol–water mixture, the applicability of these models into low viscosity fluid, such as water in nuclear engineering system, needs to be further evaluated. In the present paper, bubble in low viscosity fluid in shear flow was investigated in a full 3D numerical simulation and the volume of fluid (VOF) method was applied to capture the interface. The fluid parameter: fluid viscosity, bubble parameter: diameter and external flow parameters: shear stress magnitude and liquid velocity were examined. Comparing with bubble in high viscosity shear flow and bubble in low viscosity still flow, relative large bubble in low viscosity shear flow keep an oscillation way towards the moving wall and experienced a shape deformation process. The oscillation amplitude increased as the viscosity of fluid decreased. Small bubble migrated to the static wall in a line with larger migration velocity than that in high viscosity fluid and no deformation occurred. The shear stress triggered the oscillation behaviors while it had no direct influence with the behavior. The liquid velocity had no effect on

  18. 3D skin surface reconstruction from a single image by merging global curvature and local texture using the guided filtering for 3D haptic palpation.

    Science.gov (United States)

    Lee, K; Kim, M; Kim, K

    2018-05-11

    Skin surface evaluation has been studied using various imaging techniques. However, all these studies had limited impact because they were performed using visual exam only. To improve on this scenario with haptic feedback, we propose 3D reconstruction of the skin surface using a single image. Unlike extant 3D skin surface reconstruction algorithms, we utilize the local texture and global curvature regions, combining the results for reconstruction. The first entails the reconstruction of global curvature, achieved by bilateral filtering that removes noise on the surface while maintaining the edge (ie, furrow) to obtain the overall curvature. The second entails the reconstruction of local texture, representing the fine wrinkles of the skin, using an advanced form of bilateral filtering. The final image is then composed by merging the two reconstructed images. We tested the curvature reconstruction part by comparing the resulting curvatures with measured values from real phantom objects while local texture reconstruction was verified by measuring skin surface roughness. Then, we showed the reconstructed result of our proposed algorithm via the reconstruction of various real skin surfaces. The experimental results demonstrate that our approach is a promising technology to reconstruct an accurate skin surface with a single skin image. We proposed 3D skin surface reconstruction using only a single camera. We highlighted the utility of global curvature, which has not been considered important in the past. Thus, we proposed a new method for 3D reconstruction that can be used for 3D haptic palpation, dividing the concepts of local and global regions. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  19. A simple and effective protocol for fast isolation of human Tenon's fibroblasts from a single trabeculectomy biopsy - a comparison of cell behaviour in different culture media.

    Science.gov (United States)

    Przekora, Agata; Zarnowski, Tomasz; Ginalska, Grazyna

    2017-01-01

    Human Tenon's fibroblasts (HTFs) play a crucial role in wound healing. They cause postoperative scarring of the filtering bleb and are thus responsible for trabeculectomy failure. This study aimed to find an effective and fast protocol for HTF isolation from trabeculectomy biopsies. The protocol was compared with the commonly recommended HTF isolation procedure, which uses Dulbecco's modified Eagle's medium (DMEM). We used Eagle's minimum essential medium (EMEM) enriched with fibroblast growth factor (FGF), which selectively promoted the proliferation of HTF cells. A secondary goal was to compare HTF morphology, metabolism and growth during parallel cultivation of the isolated cells in FGF-enriched EMEM and DMEM. Standard procedures for HTF isolation from tissue biopsies require a 20- to 30-day culture of the explants to obtain the first monolayer. Our protocol yielded the first monolayer after approx. 15 days. More importantly, the majority of the cells were fibroblasts with only individual epithelium-derived cells present. Using FGF-enriched EMEM allowed 1.3 × 10 6 vimentin-positive fibroblasts to be obtained from a single biopsy within approx. 25 days. Using DMEM resulted in isolation failure and required exchange to FGF-enriched medium to recover the fibroblast culture. HTFs maintained in FGF-enriched EMEM also showed faster proliferation and a different type I collagen production ability compared to HTFs cultured in DMEM. Thus, FGF-enriched EMEM is recommended for fast propagation of HTFs unless the aim of the study is to assess the effect of a tested agent on proliferation ability or type I collagen production. Our fast protocol for HTF isolation allows easy setup of cell banks by researchers under laboratory conditions and could be very useful during testing of novel ophthalmologic anti-fibrotic agents in vitro. Molecular analysis of HTFs isolated from patients with known treatment histories may provide valuable information on the effects of some

  20. Estabilidade de produção de híbridos simples e duplos de milho oriundos de um mesmo conjunto gênico Yield stability in single and double crosses of maize originated from the same gene pool

    Directory of Open Access Journals (Sweden)

    Juarez Campolina Machado

    2008-01-01

    Full Text Available O presente trabalho foi realizado com o objetivo de comparar a estabilidade de híbridos simples e híbridos duplos de milho oriundos de um mesmo conjunto gênico. Foram avaliados 55 tratamentos, sendo dez híbridos simples comerciais, utilizados como parentais e 45 híbridos duplos resultantes de um dialelo completo. As sementes dos híbridos duplos foram obtidas na área experimental do Departamento de Biologia da Universidade Federal de Lavras (DBI/UFLA. Os experimentos foram desenvolvidos em 15 ambientes, no ano agrícola de 2005/2006, em propriedades de agricultores e estações experimentais. O delineamento experimental utilizado foi o de blocos casualizados com três repetições e o caráter avaliado foi a produtividade de espigas despalhadas (kg ha-1, corrigida para 13% de umidade. Obteve-se a contribuição de cada híbrido para a interação genótipos x ambientes e o desvio em relação ao desempenho máximo em cada ambiente utilizando a estatística não-paramétrica por meio da soma de postos. Os híbridos duplos foram, em média, mais estáveis, contudo, identificaram-se híbridos simples tão estáveis quanto os duplos.The objective of the present work was to study the adaptability and stability of single and double-crosses of maize originated from the same gene pool. Ten commercial single-crosses and all possible double-crosses, obtained from a complete diallel, were evaluated. Seeds of the double-crosses were obtained in an experimental area of the Biology Department at Universidade Federal de Lavras (DBI/UFLA. The experiments were conducted in 15 environments in the 2005/06 growing season, on farms and in experimental stations. The cultural practices were the ones normally used by farmers or experimental stations for maize. The entries were evaluated in randomized complete blocks design with three replications per environment. The trait under study was husked ears yield (kg ha-1, corrected to 13% of moisture content

  1. A single-item global job satisfaction measure is associated with quantitative blood immune indices in white-collar employees.

    Science.gov (United States)

    Nakata, Akinori; Irie, Masahiro; Takahashi, Masaya

    2013-01-01

    Although a single-item job satisfaction measure has been shown to be reliable and inclusive as multiple-item scales in relation to health, studies including immunological data are few. The purpose of this study was to evaluate the validity of single-item job and family life satisfaction based on its association with immune indices. A total of 189 white-collar employees (70% men) underwent a blood draw for the measurement of natural killer (NK), total T, and B cell counts as well as plasma immunoglobulin (Ig) G concentrations and completed single-item job and family life satisfaction measures, respectively. The response options for satisfaction measures were 'dissatisfied' (coded 1) to 'satisfied' (coded 4). Spearman's partial correlations controlling for cofactors revealed that increased job satisfaction was positively associated with NK cells (rsp=0.201, p=0.007) and IgG (rsp=0.178, p=0.018), while family life satisfaction was unrelated to immune indices. Those who reported a combination of low job/low family life satisfaction had significantly lower NK and higher B cell counts than those with a high job/high family life satisfaction. Our study suggests that the single-item summary measure of job satisfaction, but not family life satisfaction, may be a valid tool to evaluate immune status in healthy white-collar employees.

  2. Estimating rice yield related traits and quantitative trait loci analysis under different nitrogen treatments using a simple tower-based field phenotyping system with modified single-lens reflex cameras

    Science.gov (United States)

    Naito, Hiroki; Ogawa, Satoshi; Valencia, Milton Orlando; Mohri, Hiroki; Urano, Yutaka; Hosoi, Fumiki; Shimizu, Yo; Chavez, Alba Lucia; Ishitani, Manabu; Selvaraj, Michael Gomez; Omasa, Kenji

    2017-03-01

    Application of field based high-throughput phenotyping (FB-HTP) methods for monitoring plant performance in real field conditions has a high potential to accelerate the breeding process. In this paper, we discuss the use of a simple tower based remote sensing platform using modified single-lens reflex cameras for phenotyping yield traits in rice under different nitrogen (N) treatments over three years. This tower based phenotyping platform has the advantages of simplicity, ease and stability in terms of introduction, maintenance and continual operation under field conditions. Out of six phenological stages of rice analyzed, the flowering stage was the most useful in the estimation of yield performance under field conditions. We found a high correlation between several vegetation indices (simple ratio (SR), normalized difference vegetation index (NDVI), transformed vegetation index (TVI), corrected transformed vegetation index (CTVI), soil-adjusted vegetation index (SAVI) and modified soil-adjusted vegetation index (MSAVI)) and multiple yield traits (panicle number, grain weight and shoot biomass) across a three trials. Among all of the indices studied, SR exhibited the best performance in regards to the estimation of grain weight (R2 = 0.80). Under our tower-based field phenotyping system (TBFPS), we identified quantitative trait loci (QTL) for yield related traits using a mapping population of chromosome segment substitution lines (CSSLs) and a single nucleotide polymorphism data set. Our findings suggest the TBFPS can be useful for the estimation of yield performance during early crop development. This can be a major opportunity for rice breeders whom desire high throughput phenotypic selection for yield performance traits.

  3. Is simple nephrectomy truly simple? Comparison with the radical alternative.

    Science.gov (United States)

    Connolly, S S; O'Brien, M Frank; Kunni, I M; Phelan, E; Conroy, R; Thornhill, J A; Grainger, R

    2011-03-01

    The Oxford English dictionary defines the term "simple" as "easily done" and "uncomplicated". We tested the validity of this terminology in relation to open nephrectomy surgery. Retrospective review of 215 patients undergoing open, simple (n = 89) or radical (n = 126) nephrectomy in a single university-affiliated institution between 1998 and 2002. Operative time (OT), estimated blood loss (EBL), operative complications (OC) and length of stay in hospital (LOS) were analysed. Statistical analysis employed Fisher's exact test and Stata Release 8.2. Simple nephrectomy was associated with shorter OT (mean 126 vs. 144 min; p = 0.002), reduced EBL (mean 729 vs. 859 cc; p = 0.472), lower OC (9 vs. 17%; 0.087), and more brief LOS (mean 6 vs. 8 days; p < 0.001). All parameters suggest favourable outcome for the simple nephrectomy group, supporting the use of this terminology. This implies "simple" nephrectomies are truly easier to perform with less complication than their radical counterpart.

  4. Renal Transplants from Older Deceased Donors: Use of Preimplantation Biopsy and Differential Allocation to Dual or Single Kidney Transplant according to Histological Score Has No Advantages over Allocation to Single Kidney Transplant by Simple Clinical Indication

    Directory of Open Access Journals (Sweden)

    Costanza Casati

    2018-01-01

    Full Text Available Background. Grafts from elderly donors (ECD are increasingly allocated to single (SKT or dual (DKT kidney transplantation according to biopsy score. Indications and benefits of either procedure lack universal agreement. Methods. A total of 302 ECD-transplants in period from Jan 1, 2000, to Dec 31, 2015, were allocated to SKT (SKTpre on clinical grounds alone (before Dec 2010, pre-DKT era, n=170 or according to a clinical-histological protocol (after Dec 2010, DKT era, n=132 to DKT (n=48, SKT biopsy-based protocol (“high-risk”, SKThr, n=51, or SKT clinically based protocol (“low-risk”, SKTlr, n=33. Graft and patient survival were compared between the two periods and between different transplant categories. Results. Graft and overall survival in recipients from ECD in pre-DKT and DKT era did not differ (5-year graft survival 87.7% and 84.2%, resp.; equal survival in the 2 ECD periods was shown in both donor age ranges of 60–69 and >70-years, and in low-risk or high-risk ECD categories. Within the DKT protocol SKThr showed worst graft and overall survival in the 60–69 donor age range; DKT did not result in significantly better outcome than SKT from ECD in either era. One-year posttransplant creatinine clearance in recipients did not differ between any ECD transplant category. At 3 and 5 years after transplantation there were significantly higher total dialysis-free recipient life years from an equal donor number in the pre-DKT era than in the DKT protocol. Conclusions. Use of a biopsy-based protocol to allocate grafts from aged donors to SKT or DKT did not result in better short term graft survival than a clinically based protocol with allocation only to SKT and reduced overall recipient dialysis-free life years in time.

  5. Renal Transplants from Older Deceased Donors: Use of Preimplantation Biopsy and Differential Allocation to Dual or Single Kidney Transplant according to Histological Score Has No Advantages over Allocation to Single Kidney Transplant by Simple Clinical Indication.

    Science.gov (United States)

    Casati, Costanza; Colombo, Valeriana Giuseppina; Perrino, Marialuisa; Rossetti, Ornella Marina; Querques, Marialuisa; Giacomoni, Alessandro; Binaggia, Agnese; Colussi, Giacomo

    2018-01-01

    Grafts from elderly donors (ECD) are increasingly allocated to single (SKT) or dual (DKT) kidney transplantation according to biopsy score. Indications and benefits of either procedure lack universal agreement. A total of 302 ECD-transplants in period from Jan 1, 2000, to Dec 31, 2015, were allocated to SKT (SKT pre ) on clinical grounds alone (before Dec 2010, pre-DKT era, n = 170) or according to a clinical-histological protocol (after Dec 2010, DKT era, n = 132) to DKT ( n = 48), SKT biopsy-based protocol ("high-risk", SKT hr , n = 51), or SKT clinically based protocol ("low-risk", SKT lr , n = 33). Graft and patient survival were compared between the two periods and between different transplant categories. Graft and overall survival in recipients from ECD in pre-DKT and DKT era did not differ (5-year graft survival 87.7% and 84.2%, resp.); equal survival in the 2 ECD periods was shown in both donor age ranges of 60-69 and >70-years, and in low-risk or high-risk ECD categories. Within the DKT protocol SKT hr showed worst graft and overall survival in the 60-69 donor age range; DKT did not result in significantly better outcome than SKT from ECD in either era. One-year posttransplant creatinine clearance in recipients did not differ between any ECD transplant category. At 3 and 5 years after transplantation there were significantly higher total dialysis-free recipient life years from an equal donor number in the pre-DKT era than in the DKT protocol. Use of a biopsy-based protocol to allocate grafts from aged donors to SKT or DKT did not result in better short term graft survival than a clinically based protocol with allocation only to SKT and reduced overall recipient dialysis-free life years in time.

  6. Isolating the Roles of Different Forcing Agents in Global Stratospheric Temperature Changes Using Model Integrations with Incrementally Added Single Forcings

    Science.gov (United States)

    Aquila, V.; Swartz, W. H.; Waugh, D. W.; Colarco, P. R.; Pawson, S.; Polvani, L. M.; Stolarski, R. S.

    2016-01-01

    Satellite instruments show a cooling of global stratospheric temperatures over the whole data record (1979-2014). This cooling is not linear and includes two descending steps in the early 1980s and mid-1990s. The 1979-1995 period is characterized by increasing concentrations of ozone depleting substances (ODS) and by the two major volcanic eruptions of El Chichon (1982) and Mount Pinatubo (1991). The 1995-present period is characterized by decreasing ODS concentrations and by the absence of major volcanic eruptions. Greenhouse gas (GHG) concentrations increase over the whole time period. In order to isolate the roles of different forcing agents in the global stratospheric temperature changes, we performed a set of AMIP-style simulations using the NASA Goddard Earth Observing System Chemistry-Climate Model (GEOSCCM). We find that in our model simulations the cooling of the stratosphere from 1979 to present is mostly driven by changes in GHG concentrations in the middle and upper stratosphere and by GHG and ODS changes in the lower stratosphere. While the cooling trend caused by increasing GHGs is roughly constant over the satellite era, changing ODS concentrations cause a significant stratospheric cooling only up to the mid-1990s, when they start to decrease because of the implementation of the Montreal Protocol. Sporadic volcanic events and the solar cycle have a distinct signature in the time series of stratospheric temperature anomalies but do not play a statistically significant role in the long-term trends from 1979 to 2014. Several factors combine to produce the step-like behavior in the stratospheric temperatures: in the lower stratosphere, the flattening starting in the mid-1990s is due to the decrease in ozone-depleting substances; Mount Pinatubo and the solar cycle cause the abrupt steps through the aerosol-associated warming and the volcanically induced ozone depletion. In the middle and upper stratosphere, changes in solar irradiance are largely

  7. Crescimento de mudas de pinhão-manso em resposta a adubação com superfosfato simples e pó-de-rocha Growth of jatropha seedlings in response to single superphosphate and rock-flour fertilization

    Directory of Open Access Journals (Sweden)

    Fabiano Barbosa de Souza Prates

    2012-06-01

    Full Text Available Pesquisas feitas com pó-de-rocha têm mostrado a potencialidade de alguns desses resíduos em promover o enriquecimento mineral de solos; prática definida como rochagem do solo. Ela visa aumentar a fertilidade do solo, proporcionar uma boa produtividade e maior sustentabilidade agrícola. O presente trabalho teve por objetivo avaliar o crescimento de mudas de pinhão-manso (Jatropha curcas L. em resposta a adubação do substrato com superfosfato simples e pó-de-rocha. O experimento foi instalado e conduzido no período de setembro a novembro de 2007, em casa de vegetação do Instituto de Ciências Agrárias/UFMG. Os tratamentos, em esquema fatorial 2 x 5, no delineamento em blocos casualizados, com 3 repetições, corresponderam a 2 doses de pó-de-rocha (0 e 20 kg m-3 de substrato e 5 doses de superfosfato simples (1,25; 2,5; 5,0; 7,5 e 10,0 kg m-3 de substrato. Foram avaliados: altura da planta, diâmetro do caule, relação altura da planta/diâmetro do caule, número de folhas por planta, área foliar, matéria fresca e seca da raiz e da parte aérea, matéria fresca e seca total, relação matéria seca da parte aérea/matéria seca da raiz e índice de qualidade de Dickson IQD. Os resultados mostram que não houve interação significativa entre as doses de fósforo e a de pó-de-rocha aplicadas e as variáveis estudadas. A aplicação de superfosfato simples foi significativa para altura da planta, diâmetro do caule, área foliar, matéria fresca da raiz, da parte aérea e total, respondendo positivamente até a dose máxima de fósforo aplicada.Research into rock-flour have shown the potential of some of these residues in promoting the mineral enrichment of soils; a practice defined as stonemeal soil. Such practice aims to increase soil fertility and provide good productivity and greater agricultural sustainability. The present study had as objective to evaluate the growth of jatropha seedlings (Jatropha curcas L. in response to

  8. Portable digital lock-in instrument to determine chemical constituents with single-color absorption measurements for Global Health Initiatives

    Science.gov (United States)

    Vacas-Jacques, Paulino; Linnes, Jacqueline; Young, Anna; Gerrard, Victoria; Gomez-Marquez, Jose

    2014-03-01

    Innovations in international health require the use of state-of-the-art technology to enable clinical chemistry for diagnostics of bodily fluids. We propose the implementation of a portable and affordable lock-in amplifier-based instrument that employs digital technology to perform biochemical diagnostics on blood, urine, and other fluids. The digital instrument is composed of light source and optoelectronic sensor, lock-in detection electronics, microcontroller unit, and user interface components working with either power supply or batteries. The instrument performs lock-in detection provided that three conditions are met. First, the optoelectronic signal of interest needs be encoded in the envelope of an amplitude-modulated waveform. Second, the reference signal required in the demodulation channel has to be frequency and phase locked with respect to the optoelectronic carrier signal. Third, the reference signal should be conditioned appropriately. We present three approaches to condition the signal appropriately: high-pass filtering the reference signal, precise offset tuning the reference level by low-pass filtering, and by using a voltage divider network. We assess the performance of the lock-in instrument by comparing it to a benchmark device and by determining protein concentration with single-color absorption measurements. We validate the concentration values obtained with the proposed instrument using chemical concentration measurements. Finally, we demonstrate that accurate retrieval of phase information can be achieved by using the same instrument.

  9. Portable digital lock-in instrument to determine chemical constituents with single-color absorption measurements for Global Health Initiatives

    Energy Technology Data Exchange (ETDEWEB)

    Vacas-Jacques, Paulino [Little Devices Group, SUTD-MIT International Design Center, Cambridge, Massachusetts 02139 (United States); Wellman Center for Photomedicine and Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02114 (United States); Linnes, Jacqueline [Little Devices Group, SUTD-MIT International Design Center, Cambridge, Massachusetts 02139 (United States); Biomedical Engineering Department, Boston University, Boston, Massachusetts 02215 (United States); Young, Anna; Gomez-Marquez, Jose [Little Devices Group, SUTD-MIT International Design Center, Cambridge, Massachusetts 02139 (United States); Gerrard, Victoria [Little Devices Group, SUTD-MIT International Design Center, Cambridge, Massachusetts 02139 (United States); Opportunity Lab, Singapore University for Technology and Design, Singapore 138682 (Singapore)

    2014-03-15

    Innovations in international health require the use of state-of-the-art technology to enable clinical chemistry for diagnostics of bodily fluids. We propose the implementation of a portable and affordable lock-in amplifier-based instrument that employs digital technology to perform biochemical diagnostics on blood, urine, and other fluids. The digital instrument is composed of light source and optoelectronic sensor, lock-in detection electronics, microcontroller unit, and user interface components working with either power supply or batteries. The instrument performs lock-in detection provided that three conditions are met. First, the optoelectronic signal of interest needs be encoded in the envelope of an amplitude-modulated waveform. Second, the reference signal required in the demodulation channel has to be frequency and phase locked with respect to the optoelectronic carrier signal. Third, the reference signal should be conditioned appropriately. We present three approaches to condition the signal appropriately: high-pass filtering the reference signal, precise offset tuning the reference level by low-pass filtering, and by using a voltage divider network. We assess the performance of the lock-in instrument by comparing it to a benchmark device and by determining protein concentration with single-color absorption measurements. We validate the concentration values obtained with the proposed instrument using chemical concentration measurements. Finally, we demonstrate that accurate retrieval of phase information can be achieved by using the same instrument.

  10. Simple Kidney Cysts

    Science.gov (United States)

    ... Solitary Kidney Your Kidneys & How They Work Simple Kidney Cysts What are simple kidney cysts? Simple kidney cysts are abnormal, fluid-filled ... that form in the kidneys. What are the kidneys and what do they do? The kidneys are ...

  11. Discovery and mapping of a new expressed sequence tag-single nucleotide polymorphism and simple sequence repeat panel for large-scale genetic studies and breeding of Theobroma cacao L.

    Science.gov (United States)

    Allegre, Mathilde; Argout, Xavier; Boccara, Michel; Fouet, Olivier; Roguet, Yolande; Bérard, Aurélie; Thévenin, Jean Marc; Chauveau, Aurélie; Rivallan, Ronan; Clement, Didier; Courtois, Brigitte; Gramacho, Karina; Boland-Augé, Anne; Tahi, Mathias; Umaharan, Pathmanathan; Brunel, Dominique; Lanaud, Claire

    2012-01-01

    Theobroma cacao is an economically important tree of several tropical countries. Its genetic improvement is essential to provide protection against major diseases and improve chocolate quality. We discovered and mapped new expressed sequence tag-single nucleotide polymorphism (EST-SNP) and simple sequence repeat (SSR) markers and constructed a high-density genetic map. By screening 149 650 ESTs, 5246 SNPs were detected in silico, of which 1536 corresponded to genes with a putative function, while 851 had a clear polymorphic pattern across a collection of genetic resources. In addition, 409 new SSR markers were detected on the Criollo genome. Lastly, 681 new EST-SNPs and 163 new SSRs were added to the pre-existing 418 co-dominant markers to construct a large consensus genetic map. This high-density map and the set of new genetic markers identified in this study are a milestone in cocoa genomics and for marker-assisted breeding. The data are available at http://tropgenedb.cirad.fr. PMID:22210604

  12. El uso de fotocélulas de haz simple y doble para medir la velocidad en carreras®. The use of single- and dual-beam photocells to measure the sprint time®.

    Directory of Open Access Journals (Sweden)

    Juan García-López

    2012-10-01

    Full Text Available ResuemnEl objetivo del estudio fue analizar la influencia de la tecnología de las fotocélulas en el registro de tiempo y su fiabilidad durante de carreras de velocidad de corta distancia. Participaron 25 estudiantes (20.5±0.5 años; 1.78±0.02 m; 77.5±1.8 kg que fueron evaluados en 3 días (2 de familiarización y 1 de test. Se registraron aleatoriamente 3 carreras de aceleración y 3 velocidad lanzada, cronometradas simultáneamente a los 5, 10 y 15 m por dos sistemas de fotocélulas DSD Laser System®: haz simple y doble haz. El tipo de fotocélulas utilizadas influyó en el tiempo de carrera (F=11.92 y p 0.80 a los 10 y 5 m, respectivamente. En la carrera lanzada ambos sistemas midieron prácticamente igual (diferencias de ~0.005 s, obteniendo registros fiables a los 15 y 10 m, respectivamente. En conclusión, en carreras de aceleración la distancia mínima a registrar con haz simple debe ser de 10 m, y de 5 m con haz doble, mientras que en carreras lanzadas deberían utilizarse unas distancias mínimas de 15 y 10 m, respectivamente. Futuros estudios deberían analizar la distancia óptima a la primera fotocélula en las carreras de aceleración, para aumentar la fiabilidad de la medición y facilitar la comparación entre registros de diferentes estudios.AbstractThe purpose was to analyze the influence of the timing gates’ technology on both running time performance and its reliability during short sprint distances. Twenty-five physical students participated (20.5±0.5 yr; 1.78±0.02 m; 77.5±1.8 kg, whose were evaluated during 3 separate days (2 familiarization sessions and 1 testing session. Three standing-start and 3 flying-start runs were randomized and simultaneously registered at 5, 10 and 15 m by two timing gates DSD Laser System®: single- and dual-beam. The type of timing gates affected the performance (F=11.92 y p0.80 at the distances of 10 and 5 m, respectively. During the flying-start runs, both systems obtained a very

  13. A simple, low-cost and eco-friendly approach to synthesize single-crystalline LiMn2O4 nanorods with high electrochemical performance for lithium-ion batteries

    International Nuclear Information System (INIS)

    Zhao, Hongyuan; Li, Fang; Liu, Xingquan; Xiong, Weiqiang; Chen, Bing; Shao, Huailing; Que, Dongyang; Zhang, Zheng; Wu, Yue

    2015-01-01

    The single-crystalline LiMn 2 O 4 nanorods were successfully synthesized by a simple, low-cost and eco-friendly approach in which the γ-MnOOH nanorods were prepared through a facile hydrothermal process, in which KMnO 4 was reduced by anhydrous alcohol (CH 3 CH 2 OH) without adding any template reagent or additional surfactant. The crystal structures and morphologies of synthesized materials were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM), respectively. The results showed that the γ-MnOOH nanorods had high crystallinity and well-shaped morphology with an average diameter of 200 nm and an average length of 12 μm. For the resulting LiMn 2 O 4 nanorods, the electrochemical properties were investigated by galvanostatic charge-discharge test, cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). For the optimal LiMn 2 O 4 nanorods, the initial discharge capacity was 123.5 mAh g −1 and remained 110.2 mAh g −1 after 100 cycles at 1.0 C in the voltage range of 3.20∼4.35 V. Moreover, the optimal LiMn 2 O 4 nanorods can present superior rate performance, especially the capacity recovery performance as the charge-discharge rate restores to 0.1 C from 5.0 C. Such excellent electrochemical performance could make them to be the promising cathode material for high performance lithium-ion batteries

  14. Adapting to the global shortage of cholera vaccines: targeted single dose cholera vaccine in response to an outbreak in South Sudan.

    Science.gov (United States)

    Parker, Lucy A; Rumunu, John; Jamet, Christine; Kenyi, Yona; Lino, Richard Laku; Wamala, Joseph F; Mpairwe, Allan M; Ciglenecki, Iza; Luquero, Francisco J; Azman, Andrew S; Cabrol, Jean-Clement

    2017-04-01

    Shortages of vaccines for epidemic diseases, such as cholera, meningitis, and yellow fever, have become common over the past decade, hampering efforts to control outbreaks through mass reactive vaccination campaigns. Additionally, various epidemiological, political, and logistical challenges, which are poorly documented in the literature, often lead to delays in reactive campaigns, ultimately reducing the effect of vaccination. In June 2015, a cholera outbreak occurred in Juba, South Sudan, and because of the global shortage of oral cholera vaccine, authorities were unable to secure sufficient doses to vaccinate the entire at-risk population-approximately 1 million people. In this Personal View, we document the first public health use of a reduced, single-dose regimen of oral cholera vaccine, and show the details of the decision-making process and timeline. We also make recommendations to help improve reactive vaccination campaigns against cholera, and discuss the importance of new and flexible context-specific dose regimens and vaccination strategies. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Electrocardiograph-gated single photon emission computed tomography radionuclide angiography presents good interstudy reproducibility for the quantification of global systolic right ventricular function.

    Science.gov (United States)

    Daou, Doumit; Coaguila, Carlos; Vilain, Didier

    2007-05-01

    Electrocardiograph-gated single photon emission computed tomography (SPECT) radionuclide angiography provides accurate measurement of right ventricular ejection fraction and end-diastolic and end-systolic volumes. In this study, we report the interstudy precision and reliability of SPECT radionuclide angiography for the measurement of global systolic right ventricular function using two, three-dimensional volume processing methods (SPECT-QBS, SPECT-35%). These were compared with equilibrium planar radionuclide angiography. Ten patients with chronic coronary artery disease having two SPECT and planar radionuclide angiography acquisitions were included. For the right ventricular ejection fraction, end-diastolic volume and end-systolic volume, the interstudy precision and reliability were better with SPECT-35% than with SPECT-QBS. The sample sizes needed to objectify a change in right ventricular volumes or ejection fraction were lower with SPECT-35% than with SPECT-QBS. The interstudy precision and reliability of SPECT-35% and SPECT-QBS for the right ventricle were better than those of equilibrium planar radionuclide angiography, but poorer than those previously reported for the left ventricle with SPECT radionuclide angiography on the same population. SPECT-35% and SPECT-QBS present good interstudy precision and reliability for right ventricular function, with the results favouring the use of SPECT-35%. The results are better than those of equilibrium planar radionuclide angiography, but poorer than those previously reported for the left ventricle with SPECT radionuclide angiography. They need to be confirmed in a larger population.

  16. Agronomic traits and chemical composition of single hybrids of sweet corn Caracteres agronômicos e composição química de híbridos simples de milho doce

    Directory of Open Access Journals (Sweden)

    Angela Kwiatkowski

    2011-12-01

    Full Text Available In Brazil, the greengrocery market of sweet corn has been expanding along the country. In contrast, there have been few agri-industries canning sweet corn (Zea mays because of the lack of cultivars with agronomic characteristics proper to industrial purposes. The purpose of this study was to evaluate the general combining ability (GCA of seven inbred lines of sweet corn, and the specific combining ability (SCA of their hybrid combinations based on their agronomic traits, and the chemical composition of the grain. In the growing season 2006/2007, twenty-one single hybrids were evaluated in the Iguatemi Research Station, Maringá County, Northwestern Paraná, in Brazil using a complete randomized block design with four replications. Data were subjected to the analysis of variance and the genotypes were clustered by the Scott-Knott test. We estimated the GCA and SCA effects using the Griffing's method IV with the fixed model for plant height (PH, height of ear (EH, dehusked ears yield (DEY, reducing (RS and total sugars (TS, starch (ST, proteins (PTN, ether extract (EE and fibers (FB. The inbred line L4, which was originated from the 'Doce de Cuba', had the best GCA for crop yield and grain quality and therefore should be used in the next hybrid combinations. The hybrids L4xL5 and L3xL7 were the most promising with regard to crop yield and grain quality.No Brasil, poucas indústrias envazam o milho doce (Zea mays por causa da falta de cultivares para o processamento industrial. Em compensação, o mercado de milho verde doce aumentou. O objetivo deste estudo foi avaliar a capacidade geral de combinação (CGC de sete linhagens de milho doce e da capacidade específica de combinação (CEC das combinações híbridas, com base em características agronômicas e composição química dos grãos. Os vinte e um híbridos simples foram avaliados em blocos casualizados, com quatro repetições, durante o ano agrícola 2006/2007, no distrito de Iguatemi

  17. Crossing simple resonances

    International Nuclear Information System (INIS)

    Collins, T.

    1985-08-01

    A simple criterion governs the beam distortion and/or loss of protons on a fast resonance crossing. Results from numerical integrations are illustrated for simple sextupole, octupole, and 10-pole resonances

  18. Crossing simple resonances

    Energy Technology Data Exchange (ETDEWEB)

    Collins, T.

    1985-08-01

    A simple criterion governs the beam distortion and/or loss of protons on a fast resonance crossing. Results from numerical integrations are illustrated for simple sextupole, octupole, and 10-pole resonances.

  19. Quasispecies made simple.

    Directory of Open Access Journals (Sweden)

    2005-11-01

    Full Text Available Quasispecies are clouds of genotypes that appear in a population at mutation-selection balance. This concept has recently attracted the attention of virologists, because many RNA viruses appear to generate high levels of genetic variation that may enhance the evolution of drug resistance and immune escape. The literature on these important evolutionary processes is, however, quite challenging. Here we use simple models to link mutation-selection balance theory to the most novel property of quasispecies: the error threshold-a mutation rate below which populations equilibrate in a traditional mutation-selection balance and above which the population experiences an error catastrophe, that is, the loss of the favored genotype through frequent deleterious mutations. These models show that a single fitness landscape may contain multiple, hierarchically organized error thresholds and that an error threshold is affected by the extent of back mutation and redundancy in the genotype-to-phenotype map. Importantly, an error threshold is distinct from an extinction threshold, which is the complete loss of the population through lethal mutations. Based on this framework, we argue that the lethal mutagenesis of a viral infection by mutation-inducing drugs is not a true error catastophe, but is an extinction catastrophe.

  20. The Global Programme to Eliminate Lymphatic Filariasis: History and achievements with special reference to annual single-dose treatment with diethylcarbamazine in Samoa and Fiji.

    Science.gov (United States)

    Kimura, Eisaku

    2011-03-01

    Samoa in relation to the annual single-dose MDAs revealed that low density mf carriers, who have a very low mf count of 1-20/ml of venous blood, could not play a significant role in filariasis transmission.From around 1990, studies on spaced low-dose DEC treatments and various types of combination chemotherapy with DEC and ivermectin increased. Albendazole, a well-known anti-intestinal helminths agent, was later added to the combination. The main findings of these studies with W. bancrofti are: (i) a single dose of DEC at 6 mg/kg reduced mean mf density by ca. 90% 1 year after treatment; (ii) the same dose could damage/kill adult worms; (iii) a single dose of ivermectin at ca. 400 µg/kg was more effective than DEC in reducing mf density during the first year and was similarly or less effective in the second year; (iv) ivermectin probably could not kill adult worms; (v) a single combined dose of albendazole (400 mg) and DEC (6 mg/kg) was effective to reduce mf density by 85 to nearly 100% 12-24 months after treatment; and (vi) ivermectin or albendazole included in the combination chemotherapy produced "beyond-filariasis" benefits: clearance/reduction of intestinal helminths, and, additionally, in the case of ivermectin, skin-dwelling ectoparasites.The Global Programme to Eliminate Lymphatic Filariasis (GPELF) started its worldwide activities in 2000, with the target of elimination by 2020. The basic strategy is to conduct annual single-dose MDAs for 4-6 years. In 2000-2007, a minimum of 570 million individuals were treated in 48 of 83 endemic countries. The drugs used are DEC 6 mg/kg plus albendazole 400 mg in most countries, or ivermectin 200-400 µg/kg plus albendazole 400 mg particularly in onchocerciasis endemic countries in Africa. (MDAs with DEC alone had been used in India.)The GPELF achieved impressive results in terms of parasitological cure/improvement, clinical benefits, social and economic impacts, etc. However, the most impressive result of all was the

  1. Global Climate Summaries

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Global Hourly Summaries are simple indicators of observational normals which include climatic data summarizations and frequency distributions. These typically...

  2. Global Mindset in Context

    DEFF Research Database (Denmark)

    Nielsen, Rikke Kristine

    2017-01-01

    This paper addresses the call for identification of organizational contingencies related to global mindset, exploration of different forms of global mindset and their relationship with global strategies (Osland, Bird, Mendenhall & Osland, 2006). To this end, this paper explores global mindset...... development in the context of a 3-year single case study of middle manager microfoundations of global mindset in a Danish multinational corporation working with deliberate global mindset capability development as a vehicle for strategy execution and facilitation of global performance. A force field analysis...

  3. A simple phenotypic classification for celiac disease

    Directory of Open Access Journals (Sweden)

    Ajit Sood

    2018-04-01

    Full Text Available Background/Aims : Celiac disease is a global health problem. The presentation of celiac disease has unfolded over years and it is now known that it can manifest at different ages, has varied presentations, and is prone to develop complications, if not managed properly. Although the Oslo definitions provide consensus on the various terminologies used in literature, there is no phenotypic classification providing a composite diagnosis for the disease. Methods : Various variables identified for phenotypic classification included age at diagnosis, age at onset of symptoms, clinical presentation, family history and complications. These were applied to the existing registry of 1,664 patients at Dayanand Medical College and Hospital, Ludhiana, India. In addition, age was evaluated as below 15 and below 18 years. Cross tabulations were used for the verification of the classification using the existing data. Expert opinion was sought from both international and national experts of varying fields. Results : After empirical verification, age at diagnosis was considered appropriate in between A1 (<18 and A2 (≧18. The disease presentation has been classified into 3 types–P1 (classical, P2 (non-classical and P3 (asymptomatic. Complications were considered as absent (C0 or present (C1. A single phenotypic classification based on these 3 characteristics, namely age at the diagnosis, clinical presentation, and intestinal complications (APC classification was derived. Conclusions : APC classification (age at diagnosis, presentation, complications is a simple disease explanatory classification for patients with celiac disease aimed at providing a composite diagnosis.

  4. Calculation of the detection efficiency in liquid scintillators. I.- Single negatrons emitters; Calculo de la eficiencia de deteccion en liquidos centelleadores. I. Nucleidos que se desintegran por emision simple de negatrones

    Energy Technology Data Exchange (ETDEWEB)

    Grau Malonda, A.; Garcia-torano, E.

    1981-07-01

    Counting efficiency for 62 single beta emitters has been computed from the beta energy distribution, the figure of merit and the ionization quenching. Efficiency v.s. figure of merit is plotted and tabulated. (Author) 16 refs.

  5. The “Parachute” Technique: A Simple and Effective Single-Row Procedure to Achieve an Increased Contact Area Between the Cuff-Tendon and Its Footprint

    OpenAIRE

    Natera, Luis; Consigliere, Paolo; Witney-Lagen, Caroline; Brugera, Juan; Sforza, Giuseppe; Atoun, Ehud; Levy, Ofer

    2017-01-01

    Many techniques of arthroscopic rotator cuff repair have been described. No significant differences in clinical outcomes or rerupture rates have been observed when comparing single-row with double-row methods. Not all single- and double-row repairs are the same. The details of the technique used are crucial. It has been shown that the suture-tendon interface is the weakest point of the reconstruction. Therefore, the biomechanical properties of rotator cuff repairs might be influenced more by ...

  6. Emergent biosynthetic capacity in simple microbial communities.

    Directory of Open Access Journals (Sweden)

    Hsuan-Chao Chiu

    2014-07-01

    Full Text Available Microbes have an astonishing capacity to transform their environments. Yet, the metabolic capacity of a single species is limited and the vast majority of microorganisms form complex communities and join forces to exhibit capabilities far exceeding those achieved by any single species. Such enhanced metabolic capacities represent a promising route to many medical, environmental, and industrial applications and call for the development of a predictive, systems-level understanding of synergistic microbial capacity. Here we present a comprehensive computational framework, integrating high-quality metabolic models of multiple species, temporal dynamics, and flux variability analysis, to study the metabolic capacity and dynamics of simple two-species microbial ecosystems. We specifically focus on detecting emergent biosynthetic capacity--instances in which a community growing on some medium produces and secretes metabolites that are not secreted by any member species when growing in isolation on that same medium. Using this framework to model a large collection of two-species communities on multiple media, we demonstrate that emergent biosynthetic capacity is highly prevalent. We identify commonly observed emergent metabolites and metabolic reprogramming patterns, characterizing typical mechanisms of emergent capacity. We further find that emergent secretion tends to occur in two waves, the first as soon as the two organisms are introduced, and the second when the medium is depleted and nutrients become limited. Finally, aiming to identify global community determinants of emergent capacity, we find a marked association between the level of emergent biosynthetic capacity and the functional/phylogenetic distance between community members. Specifically, we demonstrate a "Goldilocks" principle, where high levels of emergent capacity are observed when the species comprising the community are functionally neither too close, nor too distant. Taken together

  7. OMI/Aura Near UV Aerosol Optical Depth and Single Scattering Albedo Daily L3 Global 1x1 deg Lat/Lon Grid V003

    Data.gov (United States)

    National Aeronautics and Space Administration — The OMI-Aura level-3 daily global gridded (1x1 deg) near-UV Aerosol data product OMAERUVd based on the enhanced algorithm is available from the NASA Goddard Earth...

  8. The global transmission network of HIV-1.

    Science.gov (United States)

    Wertheim, Joel O; Leigh Brown, Andrew J; Hepler, N Lance; Mehta, Sanjay R; Richman, Douglas D; Smith, Davey M; Kosakovsky Pond, Sergei L

    2014-01-15

    Human immunodeficiency virus type 1 (HIV-1) is pandemic, but its contemporary global transmission network has not been characterized. A better understanding of the properties and dynamics of this network is essential for surveillance, prevention, and eventual eradication of HIV. Here, we apply a simple and computationally efficient network-based approach to all publicly available HIV polymerase sequences in the global database, revealing a contemporary picture of the spread of HIV-1 within and between countries. This approach automatically recovered well-characterized transmission clusters and extended other clusters thought to be contained within a single country across international borders. In addition, previously undescribed transmission clusters were discovered. Together, these clusters represent all known modes of HIV transmission. The extent of international linkage revealed by our comprehensive approach demonstrates the need to consider the global diversity of HIV, even when describing local epidemics. Finally, the speed of this method allows for near-real-time surveillance of the pandemic's progression.

  9. Simple WZW currents

    International Nuclear Information System (INIS)

    Fuchs, J.

    1990-08-01

    A complete classification of simple currents of WZW theory is obtained. The proof is based on an analysis of the quantum dimensions of the primary fields. Simple currents are precisely the primaries with unit quantum dimension; for WZW theories explicit formulae for the quantum dimensions can be derived so that an identification of the fields with unit quantum dimension is possible. (author). 19 refs.; 2 tabs

  10. Nondestructive assessment of single-span timber bridges using a vibration- based method

    Science.gov (United States)

    Xiping Wang; James P. Wacker; Angus M. Morison; John W. Forsman; John R. Erickson; Robert J. Ross

    2005-01-01

    This paper describes an effort to develop a global dynamic testing technique for evaluating the overall stiffness of timber bridge superstructures. A forced vibration method was used to measure the natural frequency of single-span timber bridges in the laboratory and field. An analytical model based on simple beam theory was proposed to represent the relationship...

  11. Strategy as simple rules.

    Science.gov (United States)

    Eisenhardt, K M; Sull, D N

    2001-01-01

    The success of Yahoo!, eBay, Enron, and other companies that have become adept at morphing to meet the demands of changing markets can't be explained using traditional thinking about competitive strategy. These companies have succeeded by pursuing constantly evolving strategies in market spaces that were considered unattractive according to traditional measures. In this article--the third in an HBR series by Kathleen Eisenhardt and Donald Sull on strategy in the new economy--the authors ask, what are the sources of competitive advantage in high-velocity markets? The secret, they say, is strategy as simple rules. The companies know that the greatest opportunities for competitive advantage lie in market confusion, but they recognize the need for a few crucial strategic processes and a few simple rules. In traditional strategy, advantage comes from exploiting resources or stable market positions. In strategy as simple rules, advantage comes from successfully seizing fleeting opportunities. Key strategic processes, such as product innovation, partnering, or spinout creation, place the company where the flow of opportunities is greatest. Simple rules then provide the guidelines within which managers can pursue such opportunities. Simple rules, which grow out of experience, fall into five broad categories: how- to rules, boundary conditions, priority rules, timing rules, and exit rules. Companies with simple-rules strategies must follow the rules religiously and avoid the temptation to change them too frequently. A consistent strategy helps managers sort through opportunities and gain short-term advantage by exploiting the attractive ones. In stable markets, managers rely on complicated strategies built on detailed predictions of the future. But when business is complicated, strategy should be simple.

  12. Simple Finite Sums

    KAUST Repository

    Alabdulmohsin, Ibrahim M.

    2018-03-07

    We will begin our treatment of summability calculus by analyzing what will be referred to, throughout this book, as simple finite sums. Even though the results of this chapter are particular cases of the more general results presented in later chapters, they are important to start with for a few reasons. First, this chapter serves as an excellent introduction to what summability calculus can markedly accomplish. Second, simple finite sums are encountered more often and, hence, they deserve special treatment. Third, the results presented in this chapter for simple finite sums will, themselves, be used as building blocks for deriving the most general results in subsequent chapters. Among others, we establish that fractional finite sums are well-defined mathematical objects and show how various identities related to the Euler constant as well as the Riemann zeta function can actually be derived in an elementary manner using fractional finite sums.

  13. Simple Finite Sums

    KAUST Repository

    Alabdulmohsin, Ibrahim M.

    2018-01-01

    We will begin our treatment of summability calculus by analyzing what will be referred to, throughout this book, as simple finite sums. Even though the results of this chapter are particular cases of the more general results presented in later chapters, they are important to start with for a few reasons. First, this chapter serves as an excellent introduction to what summability calculus can markedly accomplish. Second, simple finite sums are encountered more often and, hence, they deserve special treatment. Third, the results presented in this chapter for simple finite sums will, themselves, be used as building blocks for deriving the most general results in subsequent chapters. Among others, we establish that fractional finite sums are well-defined mathematical objects and show how various identities related to the Euler constant as well as the Riemann zeta function can actually be derived in an elementary manner using fractional finite sums.

  14. Excel 2010 Made Simple

    CERN Document Server

    Katz, Abbott

    2011-01-01

    Get the most out of Excel 2010 with Excel 2010 Made Simple - learn the key features, understand what's new, and utilize dozens of time-saving tips and tricks to get your job done. Over 500 screen visuals and clear-cut instructions guide you through the features of Excel 2010, from formulas and charts to navigating around a worksheet and understanding Visual Basic for Applications (VBA) and macros. Excel 2010 Made Simple takes a practical and highly effective approach to using Excel 2010, showing you the best way to complete your most common spreadsheet tasks. You'll learn how to input, format,

  15. Clusters in simple fluids

    International Nuclear Information System (INIS)

    Sator, N.

    2003-01-01

    This article concerns the correspondence between thermodynamics and the morphology of simple fluids in terms of clusters. Definitions of clusters providing a geometric interpretation of the liquid-gas phase transition are reviewed with an eye to establishing their physical relevance. The author emphasizes their main features and basic hypotheses, and shows how these definitions lead to a recent approach based on self-bound clusters. Although theoretical, this tutorial review is also addressed to readers interested in experimental aspects of clustering in simple fluids

  16. Association "Les Simples"

    OpenAIRE

    Thouzery, Michel

    2014-01-01

    Fondée par les producteurs du Syndicat Inter-Massifs pour la Production et l’Économie des Simples (S.I.M.P.L.E.S), l’association base son action sur la recherche et le maintien d’une production de qualité (herboristerie et préparations à base de plantes) qui prend en compte le respect de l’environnement et la pérennité des petits producteurs en zone de montagne. Actions de formation Stages de découverte de la flore médicinale sauvage, Stages de culture et transformation des plantes médicinale...

  17. A simple electron multiplexer

    International Nuclear Information System (INIS)

    Dobrzynski, L; Akjouj, A; Djafari-Rouhani, B; Al-Wahsh, H; Zielinski, P

    2003-01-01

    We present a simple multiplexing device made of two atomic chains coupled by two other transition metal atoms. We show that this simple atomic device can transfer electrons at a given energy from one wire to the other, leaving all other electron states unaffected. Closed-form relations between the transmission coefficients and the inter-atomic distances are given to optimize the desired directional electron ejection. Such devices can be adsorbed on insulating substrates and characterized by current surface technologies. (letter to the editor)

  18. The Bern Simple Climate Model (BernSCM) v1.0: an extensible and fully documented open-source re-implementation of the Bern reduced-form model for global carbon cycle-climate simulations

    Science.gov (United States)

    Strassmann, Kuno M.; Joos, Fortunat

    2018-05-01

    The Bern Simple Climate Model (BernSCM) is a free open-source re-implementation of a reduced-form carbon cycle-climate model which has been used widely in previous scientific work and IPCC assessments. BernSCM represents the carbon cycle and climate system with a small set of equations for the heat and carbon budget, the parametrization of major nonlinearities, and the substitution of complex component systems with impulse response functions (IRFs). The IRF approach allows cost-efficient yet accurate substitution of detailed parent models of climate system components with near-linear behavior. Illustrative simulations of scenarios from previous multimodel studies show that BernSCM is broadly representative of the range of the climate-carbon cycle response simulated by more complex and detailed models. Model code (in Fortran) was written from scratch with transparency and extensibility in mind, and is provided open source. BernSCM makes scientifically sound carbon cycle-climate modeling available for many applications. Supporting up to decadal time steps with high accuracy, it is suitable for studies with high computational load and for coupling with integrated assessment models (IAMs), for example. Further applications include climate risk assessment in a business, public, or educational context and the estimation of CO2 and climate benefits of emission mitigation options.

  19. The Bern Simple Climate Model (BernSCM v1.0: an extensible and fully documented open-source re-implementation of the Bern reduced-form model for global carbon cycle–climate simulations

    Directory of Open Access Journals (Sweden)

    K. M. Strassmann

    2018-05-01

    Full Text Available The Bern Simple Climate Model (BernSCM is a free open-source re-implementation of a reduced-form carbon cycle–climate model which has been used widely in previous scientific work and IPCC assessments. BernSCM represents the carbon cycle and climate system with a small set of equations for the heat and carbon budget, the parametrization of major nonlinearities, and the substitution of complex component systems with impulse response functions (IRFs. The IRF approach allows cost-efficient yet accurate substitution of detailed parent models of climate system components with near-linear behavior. Illustrative simulations of scenarios from previous multimodel studies show that BernSCM is broadly representative of the range of the climate–carbon cycle response simulated by more complex and detailed models. Model code (in Fortran was written from scratch with transparency and extensibility in mind, and is provided open source. BernSCM makes scientifically sound carbon cycle–climate modeling available for many applications. Supporting up to decadal time steps with high accuracy, it is suitable for studies with high computational load and for coupling with integrated assessment models (IAMs, for example. Further applications include climate risk assessment in a business, public, or educational context and the estimation of CO2 and climate benefits of emission mitigation options.

  20. Simple Driving Techniques

    DEFF Research Database (Denmark)

    Rosendahl, Mads

    2002-01-01

    -like language. Our aim is to extract a simple notion of driving and show that even in this tamed form it has much of the power of more general notions of driving. Our driving technique may be used to simplify functional programs which use function composition and will often be able to remove intermediate data...

  1. A Simple Tiltmeter

    Science.gov (United States)

    Dix, M. G.; Harrison, D. R.; Edwards, T. M.

    1982-01-01

    Bubble vial with external aluminum-foil electrodes is sensing element for simple indicating tiltmeter. To measure bubble displacement, bridge circuit detects difference in capacitance between two sensing electrodes and reference electrode. Tiltmeter was developed for experiment on forecasting seismic events by changes in Earth's magnetic field.

  2. A Simple Hydrogen Electrode

    Science.gov (United States)

    Eggen, Per-Odd

    2009-01-01

    This article describes the construction of an inexpensive, robust, and simple hydrogen electrode, as well as the use of this electrode to measure "standard" potentials. In the experiment described here the students can measure the reduction potentials of metal-metal ion pairs directly, without using a secondary reference electrode. Measurements…

  3. Structure of simple liquids

    International Nuclear Information System (INIS)

    Blain, J.F.

    1969-01-01

    The results obtained by application to argon and sodium of the two important methods of studying the structure of liquids: scattering of X-rays and neutrons, are presented on one hand. On the other hand the principal models employed for reconstituting the structure of simple liquids are exposed: mathematical models, lattice models and their derived models, experimental models. (author) [fr

  4. Simple mathematical fireworks

    International Nuclear Information System (INIS)

    De Luca, R; Faella, O

    2014-01-01

    Mathematical fireworks are reproduced in two dimensions by means of simple notions in kinematics and Newtonian mechanics. Extension of the analysis in three dimensions is proposed and the geometric figures the falling tiny particles make on the ground after explosion are determined. (paper)

  5. simple sequence repeat (SSR)

    African Journals Online (AJOL)

    In the present study, 78 mapped simple sequence repeat (SSR) markers representing 11 linkage groups of adzuki bean were evaluated for transferability to mungbean and related Vigna spp. 41 markers amplified characteristic bands in at least one Vigna species. The transferability percentage across the genotypes ranged ...

  6. A Simple Wave Driver

    Science.gov (United States)

    Temiz, Burak Kagan; Yavuz, Ahmet

    2015-01-01

    This study was done to develop a simple and inexpensive wave driver that can be used in experiments on string waves. The wave driver was made using a battery-operated toy car, and the apparatus can be used to produce string waves at a fixed frequency. The working principle of the apparatus is as follows: shortly after the car is turned on, the…

  7. Phase synchronization in inhomogeneous globally coupled map lattices

    International Nuclear Information System (INIS)

    Ho Mingchung; Hung Yaochen; Jiang, I-M.

    2004-01-01

    The study of inhomogeneous-coupled chaotic systems has attracted a lot of attention recently. With simple definition of phase, we present the phase-locking behavior in ensembles of globally coupled non-identical maps. The inhomogeneous globally coupled maps consist of logistic map and tent map simultaneously. Average phase synchronization ratios, which are used to characterize the phase coherent phenomena, depend on different coupling coefficients and chaotic parameters. By using interdependence, the relationship between a single unit and the mean field is illustrated. Moreover, we take the effect of external noise and parameter mismatch into consideration and present the results by numerical simulation

  8. Síntese de nanotubos de carbono de parede simples por sublimação de grafite em atmosfera de hélio Synthesis of single-wall nanotubes by pyrolysis of graphite in helium atmosphere

    Directory of Open Access Journals (Sweden)

    José Gino Venegas Romero

    2002-02-01

    Full Text Available Macroscopic samples of fullerene nanostructures are obtained in a modified arc furnace using the electric arc method with a Helium atmosphere at low pressures. High purity graphite rods are used as electrodes but, when drilled and the orifices filled with powders of transition metals (Fe, Co, Ni acting as catalysts, the resulting particles are carbon nanostructures of the fullerene family, known as Single Wall Nanotubes (SWNTs. They have typical diameters of 1.4 nm, lengths up to tenths of microns and they are arranged together in bundles containing several SWNTs. Those samples are observed and analyzed using Scanning Electron Microscopy (SEM and Transmission Electron Microscopy (TEM techniques.

  9. Global Geomorphology

    Science.gov (United States)

    Douglas, I.

    1985-01-01

    Any global view of landforms must include an evaluation of the link between plate tectonics and geomorphology. To explain the broad features of the continents and ocean floors, a basic distinction between the tectogene and cratogene part of the Earth's surface must be made. The tectogene areas are those that are dominated by crustal movements, earthquakes and volcanicity at the present time and are essentially those of the great mountain belts and mid ocean ridges. Cratogene areas comprise the plate interiors, especially the old lands of Gondwanaland and Laurasia. Fundamental as this division between plate margin areas and plate interiors is, it cannot be said to be a simple case of a distinction between tectonically active and stable areas. Indeed, in terms of megageomorphology, former plate margins and tectonic activity up to 600 million years ago have to be considered.

  10. Simple concurrent garbage collection almost without synchronization

    NARCIS (Netherlands)

    Hesselink, Wim H.; Lali, M.I.

    We present two simple mark and sweep algorithms, A and B, for concurrent garbage collection by a single collector running concurrently with a number of mutators that concurrently modify shared data. Both algorithms are based on the ideas of Ben-Ari's classical algorithm for on-the-fly garbage

  11. Complexity is simple!

    Science.gov (United States)

    Cottrell, William; Montero, Miguel

    2018-02-01

    In this note we investigate the role of Lloyd's computational bound in holographic complexity. Our goal is to translate the assumptions behind Lloyd's proof into the bulk language. In particular, we discuss the distinction between orthogonalizing and `simple' gates and argue that these notions are useful for diagnosing holographic complexity. We show that large black holes constructed from series circuits necessarily employ simple gates, and thus do not satisfy Lloyd's assumptions. We also estimate the degree of parallel processing required in this case for elementary gates to orthogonalize. Finally, we show that for small black holes at fixed chemical potential, the orthogonalization condition is satisfied near the phase transition, supporting a possible argument for the Weak Gravity Conjecture first advocated in [1].

  12. Unicameral (simple) bone cysts.

    Science.gov (United States)

    Baig, Rafath; Eady, John L

    2006-09-01

    Since their original description by Virchow, simple bone cysts have been studied repeatedly. Although these defects are not true neoplasms, simple bone cysts may create major structural defects of the humerus, femur, and os calcis. They are commonly discovered incidentally when x-rays are taken for other reasons or on presentation due to a pathologic fracture. Various treatment strategies have been employed, but the only reliable predictor of success of any treatment strategy is the age of the patient; those being older than 10 years of age heal their cysts at a higher rate than those under age 10. The goal of management is the formation of a bone that can withstand the stresses of use by the patient without evidence of continued bone destruction as determined by serial radiographic follow-up. The goal is not a normal-appearing x-ray, but a functionally stable bone.

  13. Information technology made simple

    CERN Document Server

    Carter, Roger

    1991-01-01

    Information Technology: Made Simple covers the full range of information technology topics, including more traditional subjects such as programming languages, data processing, and systems analysis. The book discusses information revolution, including topics about microchips, information processing operations, analog and digital systems, information processing system, and systems analysis. The text also describes computers, computer hardware, microprocessors, and microcomputers. The peripheral devices connected to the central processing unit; the main types of system software; application soft

  14. Modern mathematics made simple

    CERN Document Server

    Murphy, Patrick

    1982-01-01

    Modern Mathematics: Made Simple presents topics in modern mathematics, from elementary mathematical logic and switching circuits to multibase arithmetic and finite systems. Sets and relations, vectors and matrices, tesselations, and linear programming are also discussed.Comprised of 12 chapters, this book begins with an introduction to sets and basic operations on sets, as well as solving problems with Venn diagrams. The discussion then turns to elementary mathematical logic, with emphasis on inductive and deductive reasoning; conjunctions and disjunctions; compound statements and conditional

  15. Temperature dependence of transport coefficients of 'simple liquid ...

    African Journals Online (AJOL)

    ... has been investigated. The study carried out at two densities, r* = 0.60 and r* = 0.95. Result shows erratic variations of the shear viscosity in the two lattices structures. KeyWords: Temperature effect, face centred, simple cubic, transport properties, simple liquid. [Global Jnl Pure & Appl. Sci. Vol.9(3) 2003: 403-406] ...

  16. Measurement and decomposition of socioeconomic inequality in single and multimorbidity in older adults in China and Ghana: results from the WHO study on global AGEing and adult health (SAGE).

    Science.gov (United States)

    Kunna, Rasha; San Sebastian, Miguel; Stewart Williams, Jennifer

    2017-05-15

    Globally people are living longer and enduring non-communicable diseases (NCDs) many of which co-occur as multimorbidity. Demographic and socioeconomic factors are determinants of inequalities and inequities in health. There is a need for country-specific evidence of NCD inequalities in developing countries where populations are ageing rapidly amid economic and social change. The study measures and decomposes socioeconomic inequality in single and multiple NCD morbidity in adults aged 50 and over in China and Ghana. The data source is the World Health Organization Study on Global AGEing and Adult Health (SAGE) Wave 1 (2007-2010). Nationally representative cross-sectional data collected from adults in China (n = 11,814) and Ghana (n = 4,050) are analysed. Country populations are ranked by a socioeconomic index based on ownership of household assets. The study uses a decomposed concentration index (CI) of single and multiple NCD morbidity (multimorbidity) covering arthritis, diabetes, angina, stroke, asthma, depression, chronic lung disease and hypertension. The CI quantifies the extent of overall inequality on each morbidity measure. The decomposition utilises a regression-based approach to examine individual contributions of demographic and socioeconomic factors, or determinants, to the overall inequality. In China, the prevalence of single and multiple NCD morbidity was 64.7% and 53.4%, compared with 65.9% and 55.5% respectively in Ghana. Inequalities were significant and more highly concentrated among the poor in China (single morbidity CI = -0.0365: 95% CI = -0.0689,-0.0040; multimorbidity CI = -0.0801: 95% CI = -0.1233,-0.0368;). In Ghana inequalities were significant and more highly concentrated among the rich (single morbidity CI = 0.1182; 95% CI = 0.0697, 0.1668; multimorbidity CI = 0.1453: 95% CI = 0.0794, 0.2083). In China, rural residence contributed most to inequality in single morbidity (36.4%) and the wealth

  17. Dimensional analysis made simple

    International Nuclear Information System (INIS)

    Lira, Ignacio

    2013-01-01

    An inductive strategy is proposed for teaching dimensional analysis to second- or third-year students of physics, chemistry, or engineering. In this strategy, Buckingham's theorem is seen as a consequence and not as the starting point. In order to concentrate on the basics, the mathematics is kept as elementary as possible. Simple examples are suggested for classroom demonstrations of the power of the technique and others are put forward for homework or experimentation, but instructors are encouraged to produce examples of their own. (paper)

  18. Applied mathematics made simple

    CERN Document Server

    Murphy, Patrick

    1982-01-01

    Applied Mathematics: Made Simple provides an elementary study of the three main branches of classical applied mathematics: statics, hydrostatics, and dynamics. The book begins with discussion of the concepts of mechanics, parallel forces and rigid bodies, kinematics, motion with uniform acceleration in a straight line, and Newton's law of motion. Separate chapters cover vector algebra and coplanar motion, relative motion, projectiles, friction, and rigid bodies in equilibrium under the action of coplanar forces. The final chapters deal with machines and hydrostatics. The standard and conte

  19. Data processing made simple

    CERN Document Server

    Wooldridge, Susan

    2013-01-01

    Data Processing: Made Simple, Second Edition presents discussions of a number of trends and developments in the world of commercial data processing. The book covers the rapid growth of micro- and mini-computers for both home and office use; word processing and the 'automated office'; the advent of distributed data processing; and the continued growth of database-oriented systems. The text also discusses modern digital computers; fundamental computer concepts; information and data processing requirements of commercial organizations; and the historical perspective of the computer industry. The

  20. ASP made simple

    CERN Document Server

    Deane, Sharon

    2003-01-01

    ASP Made Simple provides a brief introduction to ASP for the person who favours self teaching and/or does not have expensive computing facilities to learn on. The book will demonstrate how the principles of ASP can be learned with an ordinary PC running Personal Web Server, MS Access and a general text editor like Notepad.After working through the material readers should be able to:* Write ASP scripts that can display changing information on a web browser* Request records from a remote database or add records to it* Check user names & passwords and take this knowledge forward, either for their

  1. Theory of simple liquids

    CERN Document Server

    Hansen, Jean-Pierre

    1986-01-01

    This book gives a comprehensive and up-to-date treatment of the theory of ""simple"" liquids. The new second edition has been rearranged and considerably expanded to give a balanced account both of basic theory and of the advances of the past decade. It presents the main ideas of modern liquid state theory in a way that is both pedagogical and self-contained. The book should be accessible to graduate students and research workers, both experimentalists and theorists, who have a good background in elementary mechanics.Key Features* Compares theoretical deductions with experimental r

  2. Single-grain 40Ar-39Ar ages of glauconies: implications for the geologic time scale and global sea level variations

    Science.gov (United States)

    Smith; Evensen; York; Odin

    1998-03-06

    The mineral series glaucony supplies 40% of the absolute-age database for the geologic time scale of the last 250 million years. However, glauconies have long been suspected of giving young potassium-argon ages on bulk samples. Laser-probe argon-argon dating shows that glaucony populations comprise grains with a wide range of ages, suggesting a period of genesis several times longer ( approximately 5 million years) than previously thought. An estimate of the age of their enclosing sediments (and therefore of time scale boundaries) is given by the oldest nonrelict grains in the glaucony populations, whereas the formation times of the younger grains appear to be modulated by global sea level.

  3. What Is a Simple Liquid?

    Directory of Open Access Journals (Sweden)

    Trond S. Ingebrigtsen

    2012-03-01

    Full Text Available This paper is an attempt to identify the real essence of simplicity of liquids in John Locke’s understanding of the term. Simple liquids are traditionally defined as many-body systems of classical particles interacting via radially symmetric pair potentials. We suggest that a simple liquid should be defined instead by the property of having strong correlations between virial and potential-energy equilibrium fluctuations in the NVT ensemble. There is considerable overlap between the two definitions, but also some notable differences. For instance, in the new definition simplicity is not a direct property of the intermolecular potential because a liquid is usually only strongly correlating in part of its phase diagram. Moreover, not all simple liquids are atomic (i.e., with radially symmetric pair potentials and not all atomic liquids are simple. The main part of the paper motivates the new definition of liquid simplicity by presenting evidence that a liquid is strongly correlating if and only if its intermolecular interactions may be ignored beyond the first coordination shell (FCS. This is demonstrated by NVT simulations of the structure and dynamics of several atomic and three molecular model liquids with a shifted-forces cutoff placed at the first minimum of the radial distribution function. The liquids studied are inverse power-law systems (r^{-n} pair potentials with n=18,6,4, Lennard-Jones (LJ models (the standard LJ model, two generalized Kob-Andersen binary LJ mixtures, and the Wahnstrom binary LJ mixture, the Buckingham model, the Dzugutov model, the LJ Gaussian model, the Gaussian core model, the Hansen-McDonald molten salt model, the Lewis-Wahnstrom ortho-terphenyl model, the asymmetric dumbbell model, and the single-point charge water model. The final part of the paper summarizes properties of strongly correlating liquids, emphasizing that these are simpler than liquids in general. Simple liquids, as defined here, may be

  4. Probabilistic simple sticker systems

    Science.gov (United States)

    Selvarajoo, Mathuri; Heng, Fong Wan; Sarmin, Nor Haniza; Turaev, Sherzod

    2017-04-01

    A model for DNA computing using the recombination behavior of DNA molecules, known as a sticker system, was introduced by by L. Kari, G. Paun, G. Rozenberg, A. Salomaa, and S. Yu in the paper entitled DNA computing, sticker systems and universality from the journal of Acta Informatica vol. 35, pp. 401-420 in the year 1998. A sticker system uses the Watson-Crick complementary feature of DNA molecules: starting from the incomplete double stranded sequences, and iteratively using sticking operations until a complete double stranded sequence is obtained. It is known that sticker systems with finite sets of axioms and sticker rules generate only regular languages. Hence, different types of restrictions have been considered to increase the computational power of sticker systems. Recently, a variant of restricted sticker systems, called probabilistic sticker systems, has been introduced [4]. In this variant, the probabilities are initially associated with the axioms, and the probability of a generated string is computed by multiplying the probabilities of all occurrences of the initial strings in the computation of the string. Strings for the language are selected according to some probabilistic requirements. In this paper, we study fundamental properties of probabilistic simple sticker systems. We prove that the probabilistic enhancement increases the computational power of simple sticker systems.

  5. Simple stochastic simulation.

    Science.gov (United States)

    Schilstra, Maria J; Martin, Stephen R

    2009-01-01

    Stochastic simulations may be used to describe changes with time of a reaction system in a way that explicitly accounts for the fact that molecules show a significant degree of randomness in their dynamic behavior. The stochastic approach is almost invariably used when small numbers of molecules or molecular assemblies are involved because this randomness leads to significant deviations from the predictions of the conventional deterministic (or continuous) approach to the simulation of biochemical kinetics. Advances in computational methods over the three decades that have elapsed since the publication of Daniel Gillespie's seminal paper in 1977 (J. Phys. Chem. 81, 2340-2361) have allowed researchers to produce highly sophisticated models of complex biological systems. However, these models are frequently highly specific for the particular application and their description often involves mathematical treatments inaccessible to the nonspecialist. For anyone completely new to the field to apply such techniques in their own work might seem at first sight to be a rather intimidating prospect. However, the fundamental principles underlying the approach are in essence rather simple, and the aim of this article is to provide an entry point to the field for a newcomer. It focuses mainly on these general principles, both kinetic and computational, which tend to be not particularly well covered in specialist literature, and shows that interesting information may even be obtained using very simple operations in a conventional spreadsheet.

  6. A Simple GPU-Accelerated Two-Dimensional MUSCL-Hancock Solver for Ideal Magnetohydrodynamics

    Science.gov (United States)

    Bard, Christopher; Dorelli, John C.

    2013-01-01

    We describe our experience using NVIDIA's CUDA (Compute Unified Device Architecture) C programming environment to implement a two-dimensional second-order MUSCL-Hancock ideal magnetohydrodynamics (MHD) solver on a GTX 480 Graphics Processing Unit (GPU). Taking a simple approach in which the MHD variables are stored exclusively in the global memory of the GTX 480 and accessed in a cache-friendly manner (without further optimizing memory access by, for example, staging data in the GPU's faster shared memory), we achieved a maximum speed-up of approx. = 126 for a sq 1024 grid relative to the sequential C code running on a single Intel Nehalem (2.8 GHz) core. This speedup is consistent with simple estimates based on the known floating point performance, memory throughput and parallel processing capacity of the GTX 480.

  7. Definição da dimensão do indivíduo solo e determinação do número de amostras simples necessário à sua representação Determination of a soil individual and the number of single samples required to represent it

    Directory of Open Access Journals (Sweden)

    André Guarçoni M.

    2006-12-01

    -se coletar 25 amostras simples, necessárias à formação de uma amostra composta representativa, num hexágono de 68,75 cm de lado e área de 1,228 m².A population consists of individuals and a correct sampling of the individuals estimates population characteristics adequately. However, to evaluate soil fertility, what would be the soil individual (sample units, and of what size? The objective of this study was to determine the dimension of the individual soil component of a particular population, in three sampling areas: under no-till or under conventional tillage before or after plowing, and to evaluate soil fertility and develop a soil sampling method, determining the number of single samples required to form a composite sample that would characterize a soil individual (sample unit. Single soil samples (5.4 cm diameter x 10 cm deep were collected along the semi-diagonals of five hexagons outlined on the selected sampling areas. The sampling hexagons had 2 m long sides and from each of the six semi-diagonals, 10 single soil samples (55 per hexagon were collected at the distances 12.5; 25.0; 37.5; 50.0; 75.0; 100.0; 112.5; 150.0 and 200.0 cm, measured from a simple central sample, to the center of the sampling spot. The single central sample was the same for the six semi-diagonals. Soil pH (H2O, available P and K, Ca2+ and Mg2+ concentrations and H + Al, equilibrium-P and organic matter were determined. The single samples were grouped successively from the hexagon center and formed nine sampling units: A (up to 18.75, B (up to 31.25, C (up to 43.75, D (up to 56.25, E (up to 81.25, F (up to 106.25, G (up to 118.75, H (up to 156.25 and I (up to 206.25 cm. Regression analysis of the means and standard deviations of the evaluated characteristics was performed considering the possible dimensions of the soil sample unit. Based on the results, the conclusion was drawn that 25 simple samples must be collected to characterize a soil individual (sample unit, for the formation of a

  8. Security Components of Globalization

    Directory of Open Access Journals (Sweden)

    Florin Iftode

    2015-05-01

    Full Text Available The objective of this paper is our intention to present what are the main connections between globalization and international security. In terms of global security we can perceive the globalization as a process by which global state is represented by the UN, with a single world system, represented by major security organizations and with global effects. We will present from the beginning the main theoretical aspects that define the phenomenon of globalization, and then our contribution in assessing the implications of this phenomenon on the regional and global security. The results of our research are materialized in the last part of the paper. They emphasize the personal assessments on how the phenomenon of globalization has direct effect on global security. When talking about government, we think of norms, rules and decisionmaking procedures in the management of international life. The value that we add to the new scientific interpretation of the definition of globalization is represented, primarily, by the valuable bibliographic used resources and the original approach on the concept that refers to the links between globalization and security. This article may be, at any time, a starting point in an interesting research direction in the field of global security.

  9. Beyond Simple Headquarters Configurations

    DEFF Research Database (Denmark)

    Dellestrand, Henrik; Kappen, Philip; Nell, Phillip Christopher

    We investigate “dual headquarters involvement”, i.e. corporate and divisional headquarters’ simultaneous involvement in subsidiaries’ innovation development projects. Analyses draw on 85 innovation projects in 23 multibusiness firms and reveal that cross-divisional innovation importance, i.......e., an innovation that is important for the firm beyond the divisional boundaries, drives dual headquarters involvement in innovation development. Contrary to expectations, on average, a non-significant effect of cross-divisional embeddedness on dual headquarters involvement is found. Yet, both cross......-divisional importance and embeddedness effects are contingent on the overall complexity of the innovation project as signified by the size of the development network. The results lend support for the notion that parenting in complex structures entails complex headquarters structures and that we need to go beyond simple...

  10. Simple relation algebras

    CERN Document Server

    Givant, Steven

    2017-01-01

    This monograph details several different methods for constructing simple relation algebras, many of which are new with this book. By drawing these seemingly different methods together, all are shown to be aspects of one general approach, for which several applications are given. These tools for constructing and analyzing relation algebras are of particular interest to mathematicians working in logic, algebraic logic, or universal algebra, but will also appeal to philosophers and theoretical computer scientists working in fields that use mathematics. The book is written with a broad audience in mind and features a careful, pedagogical approach; an appendix contains the requisite background material in relation algebras. Over 400 exercises provide ample opportunities to engage with the material, making this a monograph equally appropriate for use in a special topics course or for independent study. Readers interested in pursuing an extended background study of relation algebras will find a comprehensive treatme...

  11. A Simple Harmonic Universe

    Energy Technology Data Exchange (ETDEWEB)

    Graham, Peter W.; /Stanford U., ITP; Horn, Bart; Kachru, Shamit; /Stanford U., ITP /SLAC; Rajendran, Surjeet; /Johns Hopkins U. /Stanford U., ITP; Torroba, Gonzalo; /Stanford U., ITP /SLAC

    2011-12-14

    We explore simple but novel bouncing solutions of general relativity that avoid singularities. These solutions require curvature k = +1, and are supported by a negative cosmological term and matter with -1 < w < -1 = 3. In the case of moderate bounces (where the ratio of the maximal scale factor a{sub +} to the minimal scale factor a{sub -} is {Omicron}(1)), the solutions are shown to be classically stable and cycle through an infinite set of bounces. For more extreme cases with large a{sub +} = a{sub -}, the solutions can still oscillate many times before classical instabilities take them out of the regime of validity of our approximations. In this regime, quantum particle production also leads eventually to a departure from the realm of validity of semiclassical general relativity, likely yielding a singular crunch. We briefly discuss possible applications of these models to realistic cosmology.

  12. SIMPLE for industrial radiography

    International Nuclear Information System (INIS)

    Azhar Azmi; Abd Nassir Ibrahim; Siti Madiha Muhammad Amir; Glam Hadzir Patai Mohamad; Saidi Rajab

    2004-01-01

    The first thing industrial radiographers have to do before commencing radiography works is to determine manually the amount of correct exposure that the film need to be exposed in order to obtain the right density. The amount of exposure depends on many variables such as type of radioisotope, type of film, nature of test-object and its orientation, and specific arrangement related to object location and configuration. In many cases radiography works are rejected because of radiographs fail to meet certain reference criteria as defined in the applicable standard. One of the main reasons of radiograph rejection is due to inadequate exposure received by the films. SIMPLE is a software specially developed to facilitate the calculation of gamma-radiography exposure. By using this software and knowing radiographic parameters to be encountered during the work, it is expected that human error will be minimized, thus enhancing the quality and productivity of NDT jobs. (Author)

  13. Molecular genetics made simple

    Directory of Open Access Journals (Sweden)

    Heba Sh. Kassem

    2012-07-01

    Full Text Available Genetics have undoubtedly become an integral part of biomedical science and clinical practice, with important implications in deciphering disease pathogenesis and progression, identifying diagnostic and prognostic markers, as well as designing better targeted treatments. The exponential growth of our understanding of different genetic concepts is paralleled by a growing list of genetic terminology that can easily intimidate the unfamiliar reader. Rendering genetics incomprehensible to the clinician however, defeats the very essence of genetic research: its utilization for combating disease and improving quality of life. Herein we attempt to correct this notion by presenting the basic genetic concepts along with their usefulness in the cardiology clinic. Bringing genetics closer to the clinician will enable its harmonious incorporation into clinical care, thus not only restoring our perception of its simple and elegant nature, but importantly ensuring the maximal benefit for our patients.

  14. Molecular genetics made simple

    Science.gov (United States)

    Kassem, Heba Sh.; Girolami, Francesca; Sanoudou, Despina

    2012-01-01

    Abstract Genetics have undoubtedly become an integral part of biomedical science and clinical practice, with important implications in deciphering disease pathogenesis and progression, identifying diagnostic and prognostic markers, as well as designing better targeted treatments. The exponential growth of our understanding of different genetic concepts is paralleled by a growing list of genetic terminology that can easily intimidate the unfamiliar reader. Rendering genetics incomprehensible to the clinician however, defeats the very essence of genetic research: its utilization for combating disease and improving quality of life. Herein we attempt to correct this notion by presenting the basic genetic concepts along with their usefulness in the cardiology clinic. Bringing genetics closer to the clinician will enable its harmonious incorporation into clinical care, thus not only restoring our perception of its simple and elegant nature, but importantly ensuring the maximal benefit for our patients. PMID:25610837

  15. SIMPLE LIFE AND RELIGION

    Directory of Open Access Journals (Sweden)

    Ahmet YILDIRIM

    2014-07-01

    Full Text Available Individuals in terms of the economy in which we live is one of the most important phenomenon of the century. This phenomenon present itself as the only determinant of people's lives by entering almost makes itself felt. The mo st obvious objective needs of the economy by triggering motive is to induce people to consume . Consumer culture pervades all aspects of the situation are people . Therefore, these people have the blessing of culture , beauty and value all in the name of w hatever is consumed. This is way out of the siege of moral and religious values we have is to go back again . Referred by local cultural and religious values, based on today increasingly come to the fore and the Muslim way of life appears to be close to th e plain / lean preferred by many people life has been a way of life. Even the simple life , a way of life in the Western world , a conception of life , a philosophy, a movement as it has become widely accepted. Here in determining the Muslim way of life Pr ophet. Prophet (sa lived the kind of life a very important model, sample, and determining which direction is known. Religious values, which is the carrier of the prophets, sent to the society they have always been examples and models. Because every aspect of human life, his life style and the surrounding area has a feature. We also value his life that he has unknowingly and without learning and skills and to understand it is not possible to live our religion . We also our presentation, we mainly of Islam o utlook on life and predicted life - style, including the Prophet of Islam 's (sa simple life to scrutinize and lifestyle issues related to reveal , in short Islam's how life has embraced and the Prophet. Prophet's will try to find answers to questions reg arding how to live.

  16. A SYSTEMATIC SEARCH FOR COROTATING INTERACTION REGIONS IN APPARENTLY SINGLE GALACTIC WOLF-RAYET STARS. II. A GLOBAL VIEW OF THE WIND VARIABILITY

    International Nuclear Information System (INIS)

    Chene, A.-N.; St-Louis, N.

    2011-01-01

    This study is the second part of a survey searching for large-scale spectroscopic variability in apparently single Wolf-Rayet (WR) stars. In a previous paper (Paper I), we described and characterized the spectroscopic variability level of 25 WR stars observable from the northern hemisphere and found 3 new candidates presenting large-scale wind variability, potentially originating from large-scale structures named corotating interaction regions (CIRs). In this second paper, we discuss an additional 39 stars observable from the southern hemisphere. For each star in our sample, we obtained 4-5 high-resolution spectra with a signal-to-noise ratio of ∼100 and determined its variability level using the approach described in Paper I. In total, 10 new stars are found to show large-scale spectral variability of which 7 present CIR-type changes (WR 8, WR 44, WR55, WR 58, WR 61, WR 63, WR 100). Of the remaining stars, 20 were found to show small-amplitude changes and 9 were found to show no spectral variability as far as can be concluded from the data on hand. Also, we discuss the spectroscopic variability level of all single galactic WR stars that are brighter than v ∼ 12.5, and some WR stars with 12.5 < v ≤ 13.5, i.e., all the stars presented in our two papers and four more stars for which spectra have already been published in the literature. We find that 23/68 stars (33.8%) present large-scale variability, but only 12/54 stars (∼22.1%) are potentially of CIR type. Also, we find that 31/68 stars (45.6%) only show small-scale variability, most likely due to clumping in the wind. Finally, no spectral variability is detected based on the data on hand for 14/68 (20.6%) stars. Interestingly, the variability with the highest amplitude also has the widest mean velocity dispersion.

  17. A simple scaler timer

    International Nuclear Information System (INIS)

    Narayanan, R.; Kalavathy, K.R.

    1989-01-01

    In any nuclear reactor, the start-up channels monitor the neutron flux during the start-up operation and give the alarm signals for safety purposes. Normally, a fission chamber is used as a detector to detect the low level neutron fluxes. The output of the detector after amplification and discrimination is shaped in a pulse shaper to provide constant width, constant height pulses for further processing in rate meters. The shaped pulses also go to a scaler timer, where they are counted for fixed time intervals and the accumulated counts displayed. The scaler timer described in this paper uses LSIs to get at a simple, compact and reliable unit. The design is centered around two LSIs. MOS Counter Timebase LSI type MK 5009P (U1) is used to generate the gating pulses. A 1 MHz crystal is used to generate the system clock. A 4 bit address selects the desired gating intervals of 1 or 10 or 100 seconds. In fact, MK 5009 is a very versatile LSI in a 16 pin DIP package, consisting of a MOS oscillator and divider chain. It is binary encoded for frequency division selection ranging from 1 to 36 x 10. With an input frequency of 1 MHz, MK 5009 provides the time periods of 1 μs to 100 seconds, one minute, ten minute and one hour periods. (author)

  18. A Simple Accelerometer Calibrator

    International Nuclear Information System (INIS)

    Salam, R A; Islamy, M R F; Khairurrijal; Munir, M M; Latief, H; Irsyam, M

    2016-01-01

    High possibility of earthquake could lead to the high number of victims caused by it. It also can cause other hazards such as tsunami, landslide, etc. In that case it requires a system that can examine the earthquake occurrence. Some possible system to detect earthquake is by creating a vibration sensor system using accelerometer. However, the output of the system is usually put in the form of acceleration data. Therefore, a calibrator system for accelerometer to sense the vibration is needed. In this study, a simple accelerometer calibrator has been developed using 12 V DC motor, optocoupler, Liquid Crystal Display (LCD) and AVR 328 microcontroller as controller system. The system uses the Pulse Wave Modulation (PWM) form microcontroller to control the motor rotational speed as response to vibration frequency. The frequency of vibration was read by optocoupler and then those data was used as feedback to the system. The results show that the systems could control the rotational speed and the vibration frequencies in accordance with the defined PWM. (paper)

  19. The Monash University Interactive Simple Climate Model

    Science.gov (United States)

    Dommenget, D.

    2013-12-01

    The Monash university interactive simple climate model is a web-based interface that allows students and the general public to explore the physical simulation of the climate system with a real global climate model. It is based on the Globally Resolved Energy Balance (GREB) model, which is a climate model published by Dommenget and Floeter [2011] in the international peer review science journal Climate Dynamics. The model simulates most of the main physical processes in the climate system in a very simplistic way and therefore allows very fast and simple climate model simulations on a normal PC computer. Despite its simplicity the model simulates the climate response to external forcings, such as doubling of the CO2 concentrations very realistically (similar to state of the art climate models). The Monash simple climate model web-interface allows you to study the results of more than a 2000 different model experiments in an interactive way and it allows you to study a number of tutorials on the interactions of physical processes in the climate system and solve some puzzles. By switching OFF/ON physical processes you can deconstruct the climate and learn how all the different processes interact to generate the observed climate and how the processes interact to generate the IPCC predicted climate change for anthropogenic CO2 increase. The presentation will illustrate how this web-base tool works and what are the possibilities in teaching students with this tool are.

  20. Water nanoelectrolysis: A simple model

    Science.gov (United States)

    Olives, Juan; Hammadi, Zoubida; Morin, Roger; Lapena, Laurent

    2017-12-01

    A simple model of water nanoelectrolysis—defined as the nanolocalization at a single point of any electrolysis phenomenon—is presented. It is based on the electron tunneling assisted by the electric field through the thin film of water molecules (˜0.3 nm thick) at the surface of a tip-shaped nanoelectrode (micrometric to nanometric curvature radius at the apex). By applying, e.g., an electric potential V1 during a finite time t1, and then the potential -V1 during the same time t1, we show that there are three distinct regions in the plane (t1, V1): one for the nanolocalization (at the apex of the nanoelectrode) of the electrolysis oxidation reaction, the second one for the nanolocalization of the reduction reaction, and the third one for the nanolocalization of the production of bubbles. These parameters t1 and V1 completely control the time at which the electrolysis reaction (of oxidation or reduction) begins, the duration of this reaction, the electrolysis current intensity (i.e., the tunneling current), the number of produced O2 or H2 molecules, and the radius of the nanolocalized bubbles. The model is in good agreement with our experiments.

  1. A Simple Spectral Observer

    Directory of Open Access Journals (Sweden)

    Lizeth Torres

    2018-05-01

    Full Text Available The principal aim of a spectral observer is twofold: the reconstruction of a signal of time via state estimation and the decomposition of such a signal into the frequencies that make it up. A spectral observer can be catalogued as an online algorithm for time-frequency analysis because is a method that can compute on the fly the Fourier transform (FT of a signal, without having the entire signal available from the start. In this regard, this paper presents a novel spectral observer with an adjustable constant gain for reconstructing a given signal by means of the recursive identification of the coefficients of a Fourier series. The reconstruction or estimation of a signal in the context of this work means to find the coefficients of a linear combination of sines a cosines that fits a signal such that it can be reproduced. The design procedure of the spectral observer is presented along with the following applications: (1 the reconstruction of a simple periodical signal, (2 the approximation of both a square and a triangular signal, (3 the edge detection in signals by using the Fourier coefficients, (4 the fitting of the historical Bitcoin market data from 1 December 2014 to 8 January 2018 and (5 the estimation of a input force acting upon a Duffing oscillator. To round out this paper, we present a detailed discussion about the results of the applications as well as a comparative analysis of the proposed spectral observer vis-à-vis the Short Time Fourier Transform (STFT, which is a well-known method for time-frequency analysis.

  2. Global warning, global warming

    International Nuclear Information System (INIS)

    Benarde, M.A.

    1992-01-01

    This book provides insights into the formidable array of issues which, in a warmer world, could impinge upon every facet of readers lives. It examines climatic change and long-term implications of global warming for the ecosystem. Topics include the ozone layer and how it works; the greenhouse effect; the dangers of imbalance and its effects on human and animal life; disruptions to the basic ecology of the planet; and the real scientific evidence for and against aberrant climatic shifts. The author also examines workable social and political programs and changes that must be instituted to avoid ecological disaster

  3. Vasectomy: A simple snip?

    Directory of Open Access Journals (Sweden)

    Nivedita Bhatta Dhar

    2007-01-01

    Full Text Available Vasectomy is one of the most common forms of permanent sterilization methods currently in use and has a failure rate of < 1% in most reported series. Since failure of vasectomy may result in pregnancy, adequate counseling is essential. Couples are advised that an analysis of a semen specimen after vasectomy is required to confirm success before the use of alternative contraception is abandoned. However, measuring the success of vasectomy is complicated by a lack of consistency with regards to both the number and timing of tests and the end points accepted. Materials and Methods: A Medline search was used to identify manuscripts dealing with vasectomy, with specific attempts to identify protocols designed to confirm sterility. Results and Conclusion: Vasectomy is one of the most reliable permanent methods of contraception. However, despite its popularity, certain issues pertaining to the procedure remain unresolved. Debate continues over the relative merits of the various techniques of isolating and sealing the vasal ends. Postoperative complication rates remain minimal regardless of the technique used, and no single strategy attempting to maximize patient compliance with postoperative semen analysis has enjoyed unmitigated success. Long-term consequences, other than regret, are rare.

  4. Is our world simple?

    International Nuclear Information System (INIS)

    Faessler, A.

    1991-01-01

    Grand unified models try to unify the electroweak interaction of Glashow, Salam, and Weinberg and the strong interaction of the nuclear forces (quantum-chromodynamics) into a single force. These models predict that the neutrino is identical to its antiparticle (Majorana-neutrino), that the neutrino has a mass, and that a small, right-handed, weak interaction also exists. This allows double neutrinoless beta-decay, which is forbidden in the standard model. Thus, double beta-decay without the emission of neutrinos would falsify the standard model and strongly support grand unified models. This neutrinoless double beta-decay has not yet been found but lower limits of the half-life of nuclei against the double neutrinoless beta-decay (about 10 24 years) allow to give upper limits of the neutrino mass and of the right-handedness of the weak interaction. The conditions for such limits are reliable nuclear structure calculations which are available for about 2 to 3 years. (orig.) [de

  5. Simple Synthesis Method for Alumina Nanoparticle

    Directory of Open Access Journals (Sweden)

    Daniel Damian

    2017-11-01

    Full Text Available Globally, the human population steady increase, expansion of urban areas, excessive industrialization including in agriculture, caused not only decrease to depletion of non-renewable resources, a rapid deterioration of the environment with negative impact on water quality, soil productivity and of course quality of life in general. This paper aims to prepare size controlled nanoparticles of aluminum oxide using a simple synthesis method. The morphology and dimensions of nanomaterial was investigated using modern analytical techniques: SEM/EDAX and XRD spectroscopy.

  6. Against Globalization

    DEFF Research Database (Denmark)

    Philipsen, Lotte; Baggesgaard, Mads Anders

    2013-01-01

    In order to understand globalization, we need to consider what globalization is not. That is, in order to understand the mechanisms and elements that work toward globalization, we must, in a sense, read against globalization, highlighting the limitations of the concept and its inherent conflicts....... Only by employing this as a critical practice will we be analytically able to gain a dynamic understanding of the forces of globalization as they unfold today and as they have developed historically....

  7. a simple a simple excitation control excitation control excitation

    African Journals Online (AJOL)

    eobe

    field voltages determined follow a simple quadratic relationship that offer a very simple control scheme, dependent on only the stator current. Keywords: saturated reactances, no-load field voltage, excitation control, synchronous generators. 1. Introduction. Introduction. Introduction. The commonest generator in use today is ...

  8. A simple fracture energy prediction method for fiber network based on its morphological features extracted by X-ray tomography

    International Nuclear Information System (INIS)

    Huang, Xiang; Wang, Qinghui; Zhou, Wei; Li, Jingrong

    2013-01-01

    The fracture behavior of a novel porous metal fiber sintered sheet (PMFSS) was predicted using a semi-empirical method combining the knowledge of its morphological characteristics and micro-mechanical responses. The morphological characteristics were systematically summarized based on the analysis of the topologically identical skeleton representation extracted from the X-ray tomography images. The analytical model firstly proposed by Tan et al. [1] was further modified according to the experimental observations from both tensile tests of single fibers and sintered fiber sheets, which built the coupling of single fiber segment and fiber network in terms of fracture energy using a simple prediction method. The efficacy of the prediction model was verified by comparing the predicted results to the experimental measurements. The prediction error that arose at high porosity was analyzed through fiber orientation distribution. Moreover, the tensile fracture process evolving from single fiber segments at micro-scale to the global mechanical performance was investigated

  9. Estudo da circulação hepatomesentérica pela angiografia por ressonância magnética com gadolínio: comparação entre doses simples e dupla no estudo de pacientes esquistossomóticos Gadolinium-enhanced magnetic resonance angiography for hepatomesenteric vascular evaluation: single and double doses comparison in schistosomiasis patients

    Directory of Open Access Journals (Sweden)

    Rogério Pedreschi Caldana

    2006-08-01

    Full Text Available OBJETIVO: Determinar a freqüência de visualização dos segmentos da circulação hepatomesentérica pela angiografia por ressonância magnética (angio-RM com contraste e comparar o valor do método, utilizando-se duas diferentes dosagens de gadolínio (doses simples e dupla. MATERIAIS E MÉTODOS: Estudo prospectivo de 36 pacientes esquistossomóticos submetidos a angio-RM. Os exames foram realizados em equipamento de RM de 1,5 T, usando-se bobina de corpo e bomba injetora para a administração endovenosa do contraste. Foram utilizadas, de maneira randomizada, dose dupla do contraste paramagnético (0,2 mmol/kg de Gd-DTPA em 21 pacientes e dose simples (0,1 mmol/kg em outros 15 pacientes. Os exames foram interpretados por dois observadores em consenso, que classificaram o grau de visualização de 25 segmentos vasculares estabelecidos para análise, sem conhecimento da dose de gadolínio utilizada. RESULTADOS: Os segmentos vasculares proximais e de maior calibre foram as estruturas com melhor grau de visualização na maioria da amostra em estudo. O tronco celíaco, a artéria hepática comum, a artéria esplênica, a croça e terço médio da artéria mesentérica superior, a veia porta, a veia esplênica e a veia mesentérica superior apresentaram grau 2 de visualização em mais de 70% da amostra. Quanto à comparação das diferentes dosagens, não houve diferença significante (p OBJECTIVE: To evaluate the visibility of hepatomesenteric vascular segments by 3D gadolinium-enhanced magnetic resonance (MR angiography and to compare the method effectiveness between two different gadolinium doses (single and double doses. MATERIALS AND METHODS: A prospective study was performed with 36 schistosomiasis patients who were submitted to 3D contrast-enhanced MR angiography. Scans were performed in a high-field equipment (1.5 T, with body coil and power injector for intravenous contrast administration. Contrast double doses (Gd-DTPA 0.2 mmol/kg and

  10. Corporate Stakeholding and Globalism

    DEFF Research Database (Denmark)

    Lauesen, Linne Marie

    2016-01-01

    , the global warming, the disasters of global consumerism in terms of the collapse of the Rana Plaza factory in the fashion industry, are examples of how the stakeholder concept cannot continue to be defined as narrow as corporations usually does. The butterfly effect of globalism has shown to be – yes, global....... Even the smallest company, the single consumer and the tiniest decision made by anyone may in the future – perhaps even tomorrow – affect stakeholders, we didn’t know existed. The future generation is also to be considered as stakeholders, which decisions made today may affect. Companies, consumers......, everyday people including children already know this even from the first day at school if not before. What we need is not knowledge about these phenomena – it is how to think globally when we decide locally: in companies, in daily households, in education of our future generations. This chapter discusses...

  11. Global Strategy

    DEFF Research Database (Denmark)

    Li, Peter Ping

    2013-01-01

    Global strategy differs from domestic strategy in terms of content and process as well as context and structure. The content of global strategy can contain five key elements, while the process of global strategy can have six major stages. These are expounded below. Global strategy is influenced...... by rich and complementary local contexts with diverse resource pools and game rules at the national level to form a broad ecosystem at the global level. Further, global strategy dictates the interaction or balance between different entry strategies at the levels of internal and external networks....

  12. Characterization of simple wireless neurostimulators and sensors.

    Science.gov (United States)

    Gulick, Daniel W; Towe, Bruce C

    2014-01-01

    A single diode with a wireless power source and electrodes can act as an implantable stimulator or sensor. We have built such devices using RF and ultrasound power coupling. These simple devices could drastically reduce the size, weight, and cost of implants for applications where efficiency is not critical. However, a shortcoming has been a lack of control: any movement of the external power source would change the power coupling, thereby changing the stimulation current or modulating the sensor response. To correct for changes in power and signal coupling, we propose to use harmonic signals from the device. The diode acts as a frequency multiplier, and the harmonics it emits contain information about the drive level and bias. A simplified model suggests that estimation of power, electrode bias, and electrode resistance is possible from information contained in radiated harmonics even in the presence of significant noise. We also built a simple RF-powered stimulator with an onboard voltage limiter.

  13. Seismic waves and earthquakes in a global monolithic model

    Science.gov (United States)

    Roubíček, Tomáš

    2018-03-01

    The philosophy that a single "monolithic" model can "asymptotically" replace and couple in a simple elegant way several specialized models relevant on various Earth layers is presented and, in special situations, also rigorously justified. In particular, global seismicity and tectonics is coupled to capture, e.g., (here by a simplified model) ruptures of lithospheric faults generating seismic waves which then propagate through the solid-like mantle and inner core both as shear (S) or pressure (P) waves, while S-waves are suppressed in the fluidic outer core and also in the oceans. The "monolithic-type" models have the capacity to describe all the mentioned features globally in a unified way together with corresponding interfacial conditions implicitly involved, only when scaling its parameters appropriately in different Earth's layers. Coupling of seismic waves with seismic sources due to tectonic events is thus an automatic side effect. The global ansatz is here based, rather for an illustration, only on a relatively simple Jeffreys' viscoelastic damageable material at small strains whose various scaling (limits) can lead to Boger's viscoelastic fluid or even to purely elastic (inviscid) fluid. Self-induced gravity field, Coriolis, centrifugal, and tidal forces are counted in our global model, as well. The rigorous mathematical analysis as far as the existence of solutions, convergence of the mentioned scalings, and energy conservation is briefly presented.

  14. Global Europa

    DEFF Research Database (Denmark)

    Manners, Ian

    2010-01-01

    at the mythology of ‘global Europa' - the EU in the world. It concludes with a reflection on the way in which the many diverse myths of global Europa compete for daily attention, whether as lore, ideology, or pleasure. In this respect the mythology of global Europa is part of our everyday existence, part of the EU...

  15. Drift estimation from a simple field theory

    International Nuclear Information System (INIS)

    Mendes, F. M.; Figueiredo, A.

    2008-01-01

    Given the outcome of a Wiener process, what can be said about the drift and diffusion coefficients? If the process is stationary, these coefficients are related to the mean and variance of the position displacements distribution. However, if either drift or diffusion are time-dependent, very little can be said unless some assumption about that dependency is made. In Bayesian statistics, this should be translated into some specific prior probability. We use Bayes rule to estimate these coefficients from a single trajectory. This defines a simple, and analytically tractable, field theory.

  16. Global usability

    CERN Document Server

    Douglas, Ian

    2011-01-01

    The concept of usability has become an increasingly important consideration in the design of all kinds of technology. As more products are aimed at global markets and developed through internationally distributed teams, usability design needs to be addressed in global terms. Interest in usability as a design issue and specialist area of research and education has developed steadily in North America and Europe since the 1980's. However, it is only over the last ten years that it has emerged as a global concern. Global Usability provides an introduction to the important issues in globalizing des

  17. Correcting slightly less simple movements

    Directory of Open Access Journals (Sweden)

    M.P. Aivar

    2005-01-01

    Full Text Available Many studies have analysed how goal directed movements are corrected in response to changes in the properties of the target. However, only simple movements to single targets have been used in those studies, so little is known about movement corrections under more complex situations. Evidence from studies that ask for movements to several targets in sequence suggests that whole sequences of movements are planned together. Planning related segments of a movement together makes it possible to optimise the whole sequence, but it means that some parts are planned quite long in advance, so that it is likely that they will have to be modified. In the present study we examined how people respond to changes that occur while they are moving to the first target of a sequence. Subjects moved a stylus across a digitising tablet. They moved from a specified starting point to two targets in succession. The first of these targets was always at the same position but it could have one of two sizes. The second target could be in one of two different positions and its size was different in each case. On some trials the first target changed size, and on some others the second target changed size and position, as soon as the subject started to move. When the size of the first target changed the subjects slowed down the first segment of their movements. Even the peak velocity, which was only about 150 ms after the change in size, was lower. Beside this fast response to the change itself, the dwell time at the first target was also affected: its duration increased after the change. Changing the size and position of the second target did not influence the first segment of the movement, but also increased the dwell time. The dwell time was much longer for a small target, irrespective of its initial size. If subjects knew in advance which target could change, they moved faster than if they did not know which could change. Taken together, these

  18. Simple turbulence measurements with azopolymer thin films.

    Science.gov (United States)

    Barillé, Regis; Pérez, Darío G; Morille, Yohann; Zielińska, Sonia; Ortyl, Ewelina

    2013-04-01

    A simple method to measure the influence on the laser beam propagation by a turbid medium is proposed. This measurement is based on the inscription of a surface relief grating (SRG) on an azopolymer thin film. The grating obtained with a single laser beam after propagation into a turbulent medium is perturbed and directly analyzed by a CCD camera through its diffraction pattern. Later, by scanning the surface pattern with an atomic force microscope, the inscribed SRG is analyzed with the Radon transform. This method has the advantage of using a single beam to remotely inscribe a grating detecting perturbations during the beam path. A method to evaluate the refractive index constant structure is developed.

  19. A Simple Experiment to Demonstrate the Effects of Greenhouse Gases

    Science.gov (United States)

    Keating, C. F.

    2007-01-01

    The role of greenhouse gases in our atmosphere is the subject of considerable discussion and debate. Global warming is well-documented, as is the continually increasing amount of greenhouse gases that human activity puts in the air. Is there a relationship between the two? The simple experiment described in this paper provides a good demonstration…

  20. Simple Solutions for Dry Eye

    Science.gov (United States)

    Patient Education Sheet Simple Solutions for Dry Eye The SSF thanks J. Daniel Nelson, MD, Associate Medical Director, Specialty Care HealthPartners Medical Group & Clinics, and Professor of Ophthalmology, University of ...

  1. Simple Tidal Prism Models Revisited

    Science.gov (United States)

    Luketina, D.

    1998-01-01

    Simple tidal prism models for well-mixed estuaries have been in use for some time and are discussed in most text books on estuaries. The appeal of this model is its simplicity. However, there are several flaws in the logic behind the model. These flaws are pointed out and a more theoretically correct simple tidal prism model is derived. In doing so, it is made clear which effects can, in theory, be neglected and which can not.

  2. SERE: single-parameter quality control and sample comparison for RNA-Seq.

    Science.gov (United States)

    Schulze, Stefan K; Kanwar, Rahul; Gölzenleuchter, Meike; Therneau, Terry M; Beutler, Andreas S

    2012-10-03

    Assessing the reliability of experimental replicates (or global alterations corresponding to different experimental conditions) is a critical step in analyzing RNA-Seq data. Pearson's correlation coefficient r has been widely used in the RNA-Seq field even though its statistical characteristics may be poorly suited to the task. Here we present a single-parameter test procedure for count data, the Simple Error Ratio Estimate (SERE), that can determine whether two RNA-Seq libraries are faithful replicates or globally different. Benchmarking shows that the interpretation of SERE is unambiguous regardless of the total read count or the range of expression differences among bins (exons or genes), a score of 1 indicating faithful replication (i.e., samples are affected only by Poisson variation of individual counts), a score of 0 indicating data duplication, and scores >1 corresponding to true global differences between RNA-Seq libraries. On the contrary the interpretation of Pearson's r is generally ambiguous and highly dependent on sequencing depth and the range of expression levels inherent to the sample (difference between lowest and highest bin count). Cohen's simple Kappa results are also ambiguous and are highly dependent on the choice of bins. For quantifying global sample differences SERE performs similarly to a measure based on the negative binomial distribution yet is simpler to compute. SERE can therefore serve as a straightforward and reliable statistical procedure for the global assessment of pairs or large groups of RNA-Seq datasets by a single statistical parameter.

  3. SHADOW GLOBALIZATION

    OpenAIRE

    Larissa Mihaylovna Kapitsa

    2014-01-01

    The article reviews some development trends brought about by globalization, particularly, a growing tax evasion and tax avoidance, an expansion of illicit financial flows and the proliferation of a global criminal network. The author draws attention to some new phenomena, particularly, cosmopolitanization of some parts of national elites and a deepening divide between national interests and the private interests of elites as a consequence of financial globalization. Modern mass media, both Ru...

  4. Global Mindset

    DEFF Research Database (Denmark)

    Sørensen, Olav Jull

    2016-01-01

    The concept of Global Mindset (GM) – the way to think about the global reality – is on the agenda of multinational companies concomitant with the increase in global complexity, uncertainty and diversity. In spite of a number of studies, the concept is still fluid and far from a managerial.......e. the capability to sense (quickly), reflect (constructively) and act purposefully (for mutual benefit). A case on an MNC is used at the end to show the organizational manifestations of a GM....

  5. Interfacing a one-dimensional lake model with a single-column atmospheric model: 2. Thermal response of the deep Lake Geneva, Switzerland under a 2 × CO2 global climate change

    Science.gov (United States)

    Perroud, Marjorie; Goyette, StéPhane

    2012-06-01

    In the companion to the present paper, the one-dimensional k-ɛ lake model SIMSTRAT is coupled to a single-column atmospheric model, nicknamed FIZC, and an application of the coupled model to the deep Lake Geneva, Switzerland, is described. In this paper, the response of Lake Geneva to global warming caused by an increase in atmospheric carbon dioxide concentration (i.e., 2 × CO2) is investigated. Coupling the models allowed for feedbacks between the lake surface and the atmosphere and produced changes in atmospheric moisture and cloud cover that further modified the downward radiation fluxes. The time evolution of atmospheric variables as well as those of the lake's thermal profile could be reproduced realistically by devising a set of adjustable parameters. In a "control" 1 × CO2 climate experiment, the coupled FIZC-SIMSTRAT model demonstrated genuine skills in reproducing epilimnetic and hypolimnetic temperatures, with annual mean errors and standard deviations of 0.25°C ± 0.25°C and 0.3°C ± 0.15°C, respectively. Doubling the CO2 concentration induced an atmospheric warming that impacted the lake's thermal structure, increasing the stability of the water column and extending the stratified period by 3 weeks. Epilimnetic temperatures were seen to increase by 2.6°C to 4.2°C, while hypolimnion temperatures increased by 2.2°C. Climate change modified components of the surface energy budget through changes mainly in air temperature, moisture, and cloud cover. During summer, reduced cloud cover resulted in an increase in the annual net solar radiation budget. A larger water vapor deficit at the air-water interface induced a cooling effect in the lake.

  6. A Geometry-Based Cycle Slip Detection and Repair Method with Time-Differenced Carrier Phase (TDCP for a Single Frequency Global Position System (GPS + BeiDou Navigation Satellite System (BDS Receiver

    Directory of Open Access Journals (Sweden)

    Chuang Qian

    2016-12-01

    Full Text Available As the field of high-precision applications based on carriers continues to expand, the development of low-cost, small, modular receivers and their application in diverse scenarios and situations with complex data quality has increased the requirements of carrier-phase data preprocessing. A new geometry-based cycle slip detection and repair method based on Global Position System (GPS + BeiDou Navigation Satellite System (BDS is proposed. The method uses a Time-differenced Carrier Phase (TDCP model, which eliminates the Inner-System Bias (ISB between GPS and BDS, and it is conducive to the effective combination of GPS and BDS. It avoids the interference of the noise of the pseudo-range with cycle slip detection, while the cycle slips are preserved as integers. This method does not limit the receiver frequency number, and it is applicable to single-frequency data. The process is divided into two steps to detect and repair cycle slip. The first step is cycle slip detection, using the Improved Local Analysis Method (ILAM to find satellites that have cycle slips; The second step is to repair the cycle slips, including estimating the float solution of changes in ambiguities at the satellites that have cycle slips with the least squares method and the integer solution of the cycle slips by rounding. In the process of rounding, in addition to the success probability, a decimal test is carried out to validate the result. Finally, experiments with filed test data are carried out to prove the effectiveness of this method. The results show that the detectable cycle slips number with GPS + BDS is much greater than that with GPS. The method can also detect the non-integer outliers while fixing the cycle slip. The maximum decimal bias in repair is less than that with GPS. It implies that this method takes full advantages of multi-system.

  7. Synchronization of chaos in RCL-shunted Josephson junction using a simple adaptive controller

    International Nuclear Information System (INIS)

    Guo, R; Vincent, U E; Idowu, B A

    2009-01-01

    In this paper, a simple adaptive control is proposed for the synchronization of chaotic dynamics of resistive-capacitive-inductive-shunted Josephson junctions (RCLSJ). The synchronization problem is investigated based on a drive-response system configuration consisting of two identical RCLSJ with and without identical system parameters. In addition, the synchronization when the system parameters are unknown is considered based on adaptive parameter control estimation. Sufficient conditions for global asymptotic synchronization are given and numerical simulations are employed to demonstrate the efficiency of the adaptive control scheme. In the presence of noise, we also show that the synchronization is robust and discuss the implication of our adaptive control technique in rapid single flux quantum (RSFQ) devices.

  8. The Impact of Globalization on African Conflicts

    National Research Council Canada - National Science Library

    Addo, Jonathan

    2003-01-01

    ... a cauldron of instability and economic deprivation. Globalization, which in simple terms means a worldwide network of interdependence, is a phenomenon, which emerged at the end of the Cold War and the advent of the information revolution...

  9. A Simple Calorimetric Experiment that Highlights Aspects of Global Heat Retention and Global Warming

    Science.gov (United States)

    Burley, Joel D.; Johnston, Harold S.

    2007-01-01

    In this laboratory experiment, general chemistry students measure the heating curves for three different systems: (i) 500 g of room-temperature water heated by a small desk lamp, (ii) 500 g of an ice-water mixture warmed by conduction with room-temperature surroundings, and (iii) 500 g of an ice-water mixture heated by a small desk lamp and by…

  10. Single-Arc IMRT?

    International Nuclear Information System (INIS)

    Bortfeld, Thomas; Webb, Steve

    2009-01-01

    The idea of delivering intensity-modulated radiation therapy (IMRT) with a multileaf collimator in a continuous dynamic mode during a single rotation of the gantry has recently gained momentum both in research and industry. In this note we investigate the potential of this Single-Arc IMRT technique at a conceptual level. We consider the original theoretical example case from Brahme et al that got the field of IMRT started. Using analytical methods, we derive deliverable intensity 'landscapes' for Single-Arc as well as standard IMRT and Tomotherapy. We find that Tomotherapy provides the greatest flexibility in shaping intensity landscapes and that it allows one to deliver IMRT in a way that comes close to the ideal case in the transverse plane. Single-Arc and standard IMRT make compromises in different areas. Only in relatively simple cases that do not require substantial intensity modulation will Single-Arc be dosimetrically comparable to Tomotherapy. Compared with standard IMRT, Single-Arc could be dosimetrically superior in certain cases if one is willing to accept the spreading of low dose values over large volumes of normal tissue. In terms of treatment planning, Single-Arc poses a more challenging optimization problem than Tomotherapy or standard IMRT. We conclude that Single-Arc holds potential as an efficient IMRT technique especially for relatively simple cases. In very complex cases, Single-Arc may unduly compromise the quality of the dose distribution, if one tries to keep the treatment time below 2 min or so. As with all IMRT techniques, it is important to explore the tradeoff between plan quality and the efficiency of its delivery carefully for each individual case. (note)

  11. Gendering Globalization

    DEFF Research Database (Denmark)

    Siim, Birte

    2009-01-01

    The current global financial situation bluntly and brutally brings home the fact that the global and local are closely connected in times of opportunity as well as crises. The articles in this issue of Asia Insights are about ontra-action between Asia, particularly China, and the Nordic countries...

  12. Developing Globalization

    DEFF Research Database (Denmark)

    Hansen, Annette Skovsted

    2017-01-01

    This chapter is the first qualitative micro case study of one aspect of globalization: personal networks as a concrete outcome of development assistance spending. The empirical findings related in this paper present circumstantial evidence that Japanese foreign aid has contributed to globalization...

  13. Global Uddannelse

    DEFF Research Database (Denmark)

    Jensen, Niels Rosendal

    Antologien handler om "demokratiproblemer i den globale sammenhæng" (del I) og "demokratiproblemer i uddannelse og for de offentligt ansatte" (del II), bundet sammen af et mellemstykke, der rækker ud mod begge poler både det globale og det lokale ved at knytte det til forholdet mellem marked...

  14. Simple arithmetic: not so simple for highly math anxious individuals.

    Science.gov (United States)

    Chang, Hyesang; Sprute, Lisa; Maloney, Erin A; Beilock, Sian L; Berman, Marc G

    2017-12-01

    Fluency with simple arithmetic, typically achieved in early elementary school, is thought to be one of the building blocks of mathematical competence. Behavioral studies with adults indicate that math anxiety (feelings of tension or apprehension about math) is associated with poor performance on cognitively demanding math problems. However, it remains unclear whether there are fundamental differences in how high and low math anxious individuals approach overlearned simple arithmetic problems that are less reliant on cognitive control. The current study used functional magnetic resonance imaging to examine the neural correlates of simple arithmetic performance across high and low math anxious individuals. We implemented a partial least squares analysis, a data-driven, multivariate analysis method to measure distributed patterns of whole-brain activity associated with performance. Despite overall high simple arithmetic performance across high and low math anxious individuals, performance was differentially dependent on the fronto-parietal attentional network as a function of math anxiety. Specifically, low-compared to high-math anxious individuals perform better when they activate this network less-a potential indication of more automatic problem-solving. These findings suggest that low and high math anxious individuals approach even the most fundamental math problems differently. © The Author (2017). Published by Oxford University Press.

  15. Firm Size Distribution in Fortune Global 500

    Science.gov (United States)

    Chen, Qinghua; Chen, Liujun; Liu, Kai

    By analyzing the data of Fortune Global 500 firms from 1996 to 2008, we found that their ranks and revenues always obey the same distribution, which implies that worldwide firm structure has been stable for a long time. The fitting results show that simple Zipf distribution is not an ideal model for global firms, while SCL, FSS have better fitting goodness, and lognormal fitting is the best. And then, we proposed a simple explanation.

  16. Global Mindsets

    DEFF Research Database (Denmark)

    Global Mindsets: Exploration and Perspectives seeks to tackle a topic that is relatively new in research and practice, and is considered by many to be critical for firms seeking to conduct global business. It argues that multiple mindsets exist (across and within organizations), that they operate...... in a global context, and that they are dynamic and undergo change and action. Part of the mindset(s) may depend upon place, situation and context where individuals and organizations operate. The book will examine the notion of "mindset" is situational and dynamic, especially in a global setting, why...... it is important for future scholars and managers and how it could be conceptualized. Global Mindsets: Exploration and Perspectives is split into two major sections; the first examines where the literature currently is with respect to the knowledge in the field and what conceptual frameworks guide the thinking...

  17. Global warming

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    Canada's Green Plan strategy for dealing with global warming is being implemented as a multidepartmental partnership involving all Canadians and the international community. Many of the elements of this strategy are built on an existing base of activities predating the Green Plan. Elements of the strategy include programs to limit emissions of greenhouse gases, such as initiatives to encourage more energy-efficient practices and development of alternate fuel sources; studies and policy developments to help Canadians prepare and adapt to climate change; research on the global warming phenomenon; and stimulation of international action on global warming, including obligations arising out of the Framework Convention on Climate Change. All the program elements have been approved, funded, and announced. Major achievements to date are summarized, including improvements in the Energy Efficiency Act, studies on the socioeconomic impacts of global warming, and participation in monitoring networks. Milestones associated with the remaining global warming initiatives are listed

  18. Global building physics

    DEFF Research Database (Denmark)

    Rode, Carsten

    2013-01-01

    High ambitions are set for the building physics performance of buildings today. No single technology can achieve fulfilment of these ambitions alone. Integrated, multi-facetted solutions and optimization are necessary. A holistic, or ‘global’, technological perspective is needed, which includes all...... aspects of the building as defined in building engineering. We live in an international society and building solutions are developed across country borders. Building physics is a global theme. The International Association of Building Physics has global appeal. This brief article reports the keynote...

  19. Global Building Physics

    DEFF Research Database (Denmark)

    Rode, Carsten

    2012-01-01

    High ambitions are set for the building physics performance of buildings today. No single technology can achieve fulfilment of these ambitions alone. Integrated, multi-facetted solutions and optimization are necessary. A holistic, or “global”, technological perspective is needed, which includes all...... aspects of the building as defined in building engineering. We live in an international society and building solutions are developed across country borders. Building physics is a global theme. The International Association of Building Physics has global appeal. The keynote lecture and this brief paper...

  20. Generalized Gradient Approximation Made Simple

    International Nuclear Information System (INIS)

    Perdew, J.P.; Burke, K.; Ernzerhof, M.

    1996-01-01

    Generalized gradient approximations (GGA close-quote s) for the exchange-correlation energy improve upon the local spin density (LSD) description of atoms, molecules, and solids. We present a simple derivation of a simple GGA, in which all parameters (other than those in LSD) are fundamental constants. Only general features of the detailed construction underlying the Perdew-Wang 1991 (PW91) GGA are invoked. Improvements over PW91 include an accurate description of the linear response of the uniform electron gas, correct behavior under uniform scaling, and a smoother potential. copyright 1996 The American Physical Society

  1. Coherent single-photon absorption by single emitters coupled to 1D nanophotonic waveguides

    DEFF Research Database (Denmark)

    Chen, Yuntian; Wubs, Martijn; Mørk, Jesper

    2012-01-01

    We have derived an efficient model that allows calculating the dynamical single-photon absorption of an emitter coupled to a waveguide. We suggest a novel and simple structure that leads to strong single-photon absorption.......We have derived an efficient model that allows calculating the dynamical single-photon absorption of an emitter coupled to a waveguide. We suggest a novel and simple structure that leads to strong single-photon absorption....

  2. SHADOW GLOBALIZATION

    Directory of Open Access Journals (Sweden)

    Larissa Mihaylovna Kapitsa

    2014-01-01

    Full Text Available The article reviews some development trends brought about by globalization, particularly, a growing tax evasion and tax avoidance, an expansion of illicit financial flows and the proliferation of a global criminal network. The author draws attention to some new phenomena, particularly, cosmopolitanization of some parts of national elites and a deepening divide between national interests and the private interests of elites as a consequence of financial globalization. Modern mass media, both Russian and foreign, tend to interpret globalization processes exclusively from the position of conformism, and for some of the researchers globalization became the "sacred cow", which one may only worship. Critical analysis of the processes associated with globalization is given a hostile reception. In response to criticism of globalization, one can hear the very same argument: "globalization in inevitable!" Such a state of affairs, the very least, causes perplexity. Some of the world development trends been observed over the past years raise serious concerns about the security and welfare of the peoples of the world. One of such trends has been the globalization of shadow economic activities. Methods of fight against the criminal economy been applied in international practice can be grouped into: 1 punitive enforcement (or criminal-legal methods and 2 socio-economic methods. As the results of various research works evidence punitive enforcement methods not supported by socio-economic measures not effective enough. Toughening the control over criminal economic activities in the absence of preventive and corrective actions aiming to neutralize institutional, social and other stimuli facilitating criminalization of economic activities can result in large losses of financial assets in the form of mass capital flight

  3. Shadow Globalization

    Directory of Open Access Journals (Sweden)

    Larissa Mihaylovna Kapitsa

    2014-01-01

    Full Text Available The article reviews some development trends brought about by globalization, particularly, a growing tax evasion and tax avoidance, an expansion of illicit financial flows and the proliferation of a global criminal network. The author draws attention to some new phenomena, particularly, cosmopolitanization of some parts of national elites and a deepening divide between national interests and the private interests of elites as a consequence of financial globalization. Modern mass media, both Russian and foreign, tend to interpret globalization processes exclusively from the position of conformism, and for some of the researchers globalization became the "sacred cow", which one may only worship. Critical analysis of the processes associated with globalization is given a hostile reception. In response to criticism of globalization, one can hear the very same argument: "globalization in inevitable!" Such a state of affairs, the very least, causes perplexity. Some of the world development trends been observed over the past years raise serious concerns about the security and welfare of the peoples of the world. One of such trends has been the globalization of shadow economic activities. Methods of fight against the criminal economy been applied in international practice can be grouped into: 1 punitive enforcement (or criminal-legal methods and 2 socio-economic methods. As the results of various research works evidence punitive enforcement methods not supported by socio-economic measures not effective enough. Toughening the control over criminal economic activities in the absence of preventive and corrective actions aiming to neutralize institutional, social and other stimuli facilitating criminalization of economic activities can result in large losses of financial assets in the form of mass capital flight

  4. Emergence Issues - not so simple

    African Journals Online (AJOL)

    Anaesthetics Supplement: Emergence Issues - not so simple. S Afr Fam Pract 2014. Vol 56 No 2 Supplement 1. Introduction. Emergence from anaesthesia is by definition the process of return to baseline physiological function of all organ systems after cessation of administration of general anaesthesia and is the stage from ...

  5. On framed simple Lie groups

    OpenAIRE

    MINAMI, Haruo

    2016-01-01

    For a compact simple Lie group $G$, we show that the element $[G, \\mathcal{L}] \\in \\pi^S_*(S^0)$ represented by the pair $(G, \\mathcal{L})$ is zero, where $\\mathcal{L}$ denotes the left invariant framing of $G$. The proof relies on the method of E. Ossa [Topology, 21 (1982), 315–323].

  6. The simple ethers of glycerin

    International Nuclear Information System (INIS)

    Kimsanov, B.Kh.; Karimov, M.B.

    1998-01-01

    From glycerin derivatives the considerable interest is present simple ethers because many of them are biological active and found wide practical using as an effect drugs, inters for thin organic synthesis, vehicle for injections, regulators of plants growth, reagents, components for perfumery-cosmetic goods and etc

  7. Solving Simple Kinetics without Integrals

    Science.gov (United States)

    de la Pen~a, Lisandro Herna´ndez

    2016-01-01

    The solution of simple kinetic equations is analyzed without referencing any topic from differential equations or integral calculus. Guided by the physical meaning of the rate equation, a systematic procedure is used to generate an approximate solution that converges uniformly to the exact solution in the case of zero, first, and second order…

  8. Grief: Difficult Times, Simple Steps.

    Science.gov (United States)

    Waszak, Emily Lane

    This guide presents techniques to assist others in coping with the loss of a loved one. Using the language of 9 layperson, the book contains more than 100 tips for caregivers or loved ones. A simple step is presented on each page, followed by reasons and instructions for each step. Chapters include: "What to Say"; "Helpful Things to Do"; "Dealing…

  9. Simple stålrammebygninger

    DEFF Research Database (Denmark)

    Ellum, J.C.

    Anvisningen gennemgår dimensioneringen og bringer detaljerede konstruktionstegninger til simple stålrammebygninger, dvs. lukkede, fritliggende bygninger i én etage, hvor tagkonstruktionen ud over egenlast kun er påvirket af naturlaster, dvs. sne og vind. Dimensioneringen sker ved at udfylde et di...

  10. Simple models with ALICE fluxes

    CERN Document Server

    Striet, J

    2000-01-01

    We introduce two simple models which feature an Alice electrodynamics phase. In a well defined sense the Alice flux solutions we obtain in these models obey first order equations similar to those of the Nielsen-Olesen fluxtube in the abelian higgs model in the Bogomol'nyi limit. Some numerical solutions are presented as well.

  11. Global Rome

    DEFF Research Database (Denmark)

    Is 21st-century Rome a global city? Is it part of Europe's core or periphery? This volume examines the “real city” beyond Rome's historical center, exploring the diversity and challenges of life in neighborhoods affected by immigration, neoliberalism, formal urban planning, and grassroots social...... movements. The contributors engage with themes of contemporary urban studies–the global city, the self-made city, alternative modernities, capital cities and nations, urban change from below, and sustainability. Global Rome serves as a provocative introduction to the Eternal City and makes an original...

  12. Structure of simple liquids; Structure des liquides simples

    Energy Technology Data Exchange (ETDEWEB)

    Blain, J F [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1969-07-01

    The results obtained by application to argon and sodium of the two important methods of studying the structure of liquids: scattering of X-rays and neutrons, are presented on one hand. On the other hand the principal models employed for reconstituting the structure of simple liquids are exposed: mathematical models, lattice models and their derived models, experimental models. (author) [French] On presente d'une part les resultats obtenus par application a l'argon et au sodium des deux principales methodes d'etude de la structure des liquides: la diffusion des rayons X et la diffusion des neutrons; d'autre part, les principaux modeles employes pour reconstituer la structure des liquides simples sont exposes: modeles mathematiques, modeles des reseaux et modeles derives, modeles experimentaux. (auteur)

  13. Global Managers

    DEFF Research Database (Denmark)

    Barakat, Livia L.; Lorenz, Melanie P.; Ramsey, Jase R.

    2016-01-01

    Purpose: – The purpose of this paper is to examine the effect of cultural intelligence (CQ) on the job performance of global managers. Design/methodology/approach: – In total, 332 global managers were surveyed from multinational companies operating in Brazil. The mediating effect of job...... satisfaction was tested on the CQ-job performance relationship. Findings: – The findings suggest that job satisfaction transmits the effect of CQ to job performance, such that global managers high in CQ exhibit more job satisfaction in an international setting, and therefore perform better at their jobs....... Practical implications: – Results imply that global managers should increase their CQ in order to improve their job satisfaction and ultimately perform better in an international context. Originality/value: – The authors make three primary contributions to the international business literature. First...

  14. A simple approximation method for dilute Ising systems

    International Nuclear Information System (INIS)

    Saber, M.

    1996-10-01

    We describe a simple approximate method to analyze dilute Ising systems. The method takes into consideration the fluctuations of the effective field, and is based on a probability distribution of random variables which correctly accounts for all the single site kinematic relations. It is shown that the simplest approximation gives satisfactory results when compared with other methods. (author). 12 refs, 2 tabs

  15. epilepsy following simple febrile seizure in a rural community in ...

    African Journals Online (AJOL)

    2011-12-12

    Dec 12, 2011 ... family history of epilepsy did not significantly influence the development of later epilepsy X2 ... following a single simple febrile seizure. MATERIALS ANd ... If the parent did not witness the seizure, an adult who witnessed the ...

  16. How to observe simple structures in deep inelastic reactions

    International Nuclear Information System (INIS)

    Frascaria, N.

    1981-10-01

    Evidence is presented for the observation of simple structures at high excitation energy in the energy spectra of fragments from numerous ion reactions. Techniques employed in the single as well as in the coincidence experiments are discussed. The main characteristics of these structures are pointed out and some possible interpretations of the experimental observations are given

  17. Good results after laparoscopic marsupialisation of simple liver cysts

    DEFF Research Database (Denmark)

    Nørregaard, Christian Lolle; Ainsworth, Alan Patrick

    2014-01-01

    INTRODUCTION: Large simple liver cysts often tend to be symptomatic with pain being the most common symptom. MATERIAL AND METHODS: This was a retrospective study of patients who had intended laparoscopic surgery for liver cysts between December 2007 and December 2012 at a single institution...

  18. Advanced statistics: linear regression, part I: simple linear regression.

    Science.gov (United States)

    Marill, Keith A

    2004-01-01

    Simple linear regression is a mathematical technique used to model the relationship between a single independent predictor variable and a single dependent outcome variable. In this, the first of a two-part series exploring concepts in linear regression analysis, the four fundamental assumptions and the mechanics of simple linear regression are reviewed. The most common technique used to derive the regression line, the method of least squares, is described. The reader will be acquainted with other important concepts in simple linear regression, including: variable transformations, dummy variables, relationship to inference testing, and leverage. Simplified clinical examples with small datasets and graphic models are used to illustrate the points. This will provide a foundation for the second article in this series: a discussion of multiple linear regression, in which there are multiple predictor variables.

  19. Globalization & technology

    DEFF Research Database (Denmark)

    Narula, Rajneesh

    Technology and globalization are interdependent processes. Globalization has a fundamental influence on the creation and diffusion of technology, which, in turn, affects the interdependence of firms and locations. This volume examines the international aspect of this interdependence at two levels...... of innovation" understanding of learning. Narula and Smith reconcile an important paradox. On the one hand, locations and firms are increasingly interdependent through supranational organisations, regional integration, strategic alliances, and the flow of investments, technologies, ideas and people...

  20. Another globalization

    OpenAIRE

    Prof. Ph.D. Ion Bucur

    2007-01-01

    Finding the anachronisms and the failures of the present globalization, as well as the vitiated system of world-wide government, has stimulated the debates regarding the identification of a more equitable form of globalization to favor the acceleration of the economic increase and the reduction of poverty.The deficiency of the present international economic institutions, especially the lack of transparency and democratic responsibility, claims back with acuteness the reformation of ...

  1. Gendered globalization

    DEFF Research Database (Denmark)

    Milwertz, Cecilia Nathansen; Cai, Yiping

    2017-01-01

    Both the People’s Republic of China (PRC) and Nordic countries (Sweden, Iceland, Denmark, Norway and Finland) view gender equality as a social justice issue and are politically committed towards achieving gender equality nationally and internationally. Since China has taken a proactive position...... on globalization and global governance, gender equality is possibly an area that China may wish to explore in collaboration with the Nordic countries....

  2. Global warming

    CERN Document Server

    Hulme, M

    1998-01-01

    Global warming-like deforestation, the ozone hole and the loss of species- has become one of the late 20the century icons of global environmental damage. The threat, is not the reality, of such a global climate change has motivated governments. businesses and environmental organisations, to take serious action ot try and achieve serious control of the future climate. This culminated last December in Kyoto in the agreement for legally-binding climate protocol. In this series of three lectures I will provide a perspective on the phenomenon of global warming that accepts the scientific basis for our concern, but one that also recognises the dynamic interaction between climate and society that has always exited The future will be no different. The challenge of global warning is not to pretend it is not happening (as with some pressure groups), nor to pretend it threatens global civilisation (as with other pressure groups), and it is not even a challenge to try and stop it from happening-we are too far down the ro...

  3. Reaction chemistry of nitrogen species in hydrothermal systems: Simple reactions, waste simulants, and actual wastes

    International Nuclear Information System (INIS)

    Dell'Orco, P.; Luan, L.; Proesmans, P.; Wilmanns, E.

    1995-01-01

    Results are presented from hydrothermal reaction systems containing organic components, nitrogen components, and an oxidant. Reaction chemistry observed in simple systems and in simple waste simulants is used to develop a model which presents global nitrogen chemistry in these reactive systems. The global reaction path suggested is then compared with results obtained for the treatment of an actual waste stream containing only C-N-0-H species

  4. Simple spatial scaling rules behind complex cities.

    Science.gov (United States)

    Li, Ruiqi; Dong, Lei; Zhang, Jiang; Wang, Xinran; Wang, Wen-Xu; Di, Zengru; Stanley, H Eugene

    2017-11-28

    Although most of wealth and innovation have been the result of human interaction and cooperation, we are not yet able to quantitatively predict the spatial distributions of three main elements of cities: population, roads, and socioeconomic interactions. By a simple model mainly based on spatial attraction and matching growth mechanisms, we reveal that the spatial scaling rules of these three elements are in a consistent framework, which allows us to use any single observation to infer the others. All numerical and theoretical results are consistent with empirical data from ten representative cities. In addition, our model can also provide a general explanation of the origins of the universal super- and sub-linear aggregate scaling laws and accurately predict kilometre-level socioeconomic activity. Our work opens a new avenue for uncovering the evolution of cities in terms of the interplay among urban elements, and it has a broad range of applications.

  5. Search without Boundaries Using Simple APIs

    Science.gov (United States)

    Tong, Qi

    2009-01-01

    The U.S. Geological Survey (USGS) Library, where the author serves as the digital services librarian, is increasingly challenged to make it easier for users to find information from many heterogeneous information sources. Information is scattered throughout different software applications (i.e., library catalog, federated search engine, link resolver, and vendor websites), and each specializes in one thing. How could the library integrate the functionalities of one application with another and provide a single point of entry for users to search across? To improve the user experience, the library launched an effort to integrate the federated search engine into the library's intranet website. The result is a simple search box that leverages the federated search engine's built-in application programming interfaces (APIs). In this article, the author describes how this project demonstrated the power of APIs and their potential to be used by other enterprise search portals inside or outside of the library.

  6. Simple implementation of general dark energy models

    International Nuclear Information System (INIS)

    Bloomfield, Jolyon K.; Pearson, Jonathan A.

    2014-01-01

    We present a formalism for the numerical implementation of general theories of dark energy, combining the computational simplicity of the equation of state for perturbations approach with the generality of the effective field theory approach. An effective fluid description is employed, based on a general action describing single-scalar field models. The formalism is developed from first principles, and constructed keeping the goal of a simple implementation into CAMB in mind. Benefits of this approach include its straightforward implementation, the generality of the underlying theory, the fact that the evolved variables are physical quantities, and that model-independent phenomenological descriptions may be straightforwardly investigated. We hope this formulation will provide a powerful tool for the comparison of theoretical models of dark energy with observational data

  7. Simple Electromagnetic Analysis in Cryptography

    Directory of Open Access Journals (Sweden)

    Zdenek Martinasek

    2012-07-01

    Full Text Available The article describes the main principle and methods of simple electromagnetic analysis and thus provides an overview of simple electromagnetic analysis.The introductions chapters describe specific SPA attack used visual inspection of EM traces, template based attack and collision attack.After reading the article, the reader is sufficiently informed of any context of SEMA.Another aim of the article is the practical realization of SEMA which is focused on AES implementation.The visual inspection of EM trace of AES is performed step by step and the result is the determination of secret key Hamming weight.On the resulting EM trace, the Hamming weight of the secret key 1 to 8 was clearly visible.This method allows reduction from the number of possible keys for following brute force attack.

  8. Complexity-aware simple modeling.

    Science.gov (United States)

    Gómez-Schiavon, Mariana; El-Samad, Hana

    2018-02-26

    Mathematical models continue to be essential for deepening our understanding of biology. On one extreme, simple or small-scale models help delineate general biological principles. However, the parsimony of detail in these models as well as their assumption of modularity and insulation make them inaccurate for describing quantitative features. On the other extreme, large-scale and detailed models can quantitatively recapitulate a phenotype of interest, but have to rely on many unknown parameters, making them often difficult to parse mechanistically and to use for extracting general principles. We discuss some examples of a new approach-complexity-aware simple modeling-that can bridge the gap between the small-scale and large-scale approaches. Copyright © 2018 Elsevier Ltd. All rights reserved.

  9. Simple Functions Spreadsheet tool presentation

    International Nuclear Information System (INIS)

    Grive, Mireia; Domenech, Cristina; Montoya, Vanessa; Garcia, David; Duro, Lara

    2010-09-01

    This document is a guide for users of the Simple Functions Spreadsheet tool. The Simple Functions Spreadsheet tool has been developed by Amphos 21 to determine the solubility limits of some radionuclides and it has been especially designed for Performance Assessment exercises. The development of this tool has been promoted by the necessity expressed by SKB of having a confident and easy-to-handle tool to calculate solubility limits in an agile and relatively fast manner. Its development started in 2005 and since then, it has been improved until the current version. This document describes the accurate and preliminary study following expert criteria that has been used to select the simplified aqueous speciation and solid phase system included in the tool. This report also gives the basic instructions to use this tool and to interpret its results. Finally, this document also reports the different validation tests and sensitivity analyses that have been done during the verification process

  10. Gradings on simple Lie algebras

    CERN Document Server

    Elduque, Alberto

    2013-01-01

    Gradings are ubiquitous in the theory of Lie algebras, from the root space decomposition of a complex semisimple Lie algebra relative to a Cartan subalgebra to the beautiful Dempwolff decomposition of E_8 as a direct sum of thirty-one Cartan subalgebras. This monograph is a self-contained exposition of the classification of gradings by arbitrary groups on classical simple Lie algebras over algebraically closed fields of characteristic not equal to 2 as well as on some nonclassical simple Lie algebras in positive characteristic. Other important algebras also enter the stage: matrix algebras, the octonions, and the Albert algebra. Most of the presented results are recent and have not yet appeared in book form. This work can be used as a textbook for graduate students or as a reference for researchers in Lie theory and neighboring areas.

  11. Licensing of simple digital devices

    International Nuclear Information System (INIS)

    Jackson, T. W.

    2008-01-01

    The inability to guarantee error-free software gave rise to the potential for common-cause failure of digital safety systems in nuclear power plants. To address this vulnerability, the U. S. Nuclear Regulatory Commission (NRC) required a quality software development process and a defense-in-depth and diversity analysis for digital safety systems. As a result of recent interim [NRC] staff guidance in the digital instrumentation and control (I and C) area, licensing of simple digital devices decreases some regulatory burden with respect to demonstrating a quality software development process and defense-in-depth and diversity analysis. This paper defines simple digital devices and addresses the interim staff guidance that applies to such devices. The paper also highlights the technical aspects that affect the licensing of such devices and incorporates licensing experience in the U.S. to date. (authors)

  12. A simple electron plasma wave

    International Nuclear Information System (INIS)

    Brodin, G.; Stenflo, L.

    2017-01-01

    Considering a class of solutions where the density perturbations are functions of time, but not of space, we derive a new exact large amplitude wave solution for a cold uniform electron plasma. This result illustrates that most simple analytical solutions can appear even if the density perturbations are large. - Highlights: • The influence of large amplitude electromagnetic waves on electrostatic oscillations is found. • A generalized Mathieu equation is derived. • Anharmonic wave profiles are computed numerically.

  13. A Simple Probabilistic Combat Model

    Science.gov (United States)

    2016-06-13

    Government may violate any copyrights that exist in this work. This page intentionally left blank. ABSTRACT The Lanchester ...page intentionally left blank. TABLE OF CONTENTS Page No.Abstract iii List of Illustrations vii 1. INTRODUCTION 1 2. DETERMINISTIC LANCHESTER MODEL...This page intentionally left blank. 1. INTRODUCTION The Lanchester combat model1 is a simple way to assess the effects of quantity and quality

  14. A simple electron plasma wave

    Energy Technology Data Exchange (ETDEWEB)

    Brodin, G., E-mail: gert.brodin@physics.umu.se [Department of Physics, Umeå University, SE-901 87 Umeå (Sweden); Stenflo, L. [Department of Physics, Linköping University, SE-581 83 Linköping (Sweden)

    2017-03-18

    Considering a class of solutions where the density perturbations are functions of time, but not of space, we derive a new exact large amplitude wave solution for a cold uniform electron plasma. This result illustrates that most simple analytical solutions can appear even if the density perturbations are large. - Highlights: • The influence of large amplitude electromagnetic waves on electrostatic oscillations is found. • A generalized Mathieu equation is derived. • Anharmonic wave profiles are computed numerically.

  15. Simple and Realistic Data Generation

    DEFF Research Database (Denmark)

    Pedersen, Kenneth Houkjær; Torp, Kristian; Wind, Rico

    2006-01-01

    This paper presents a generic, DBMS independent, and highly extensible relational data generation tool. The tool can efficiently generate realistic test data for OLTP, OLAP, and data streaming applications. The tool uses a graph model to direct the data generation. This model makes it very simple...... to generate data even for large database schemas with complex inter- and intra table relationships. The model also makes it possible to generate data with very accurate characteristics....

  16. Classification of simple current invariants

    CERN Document Server

    Gato-Rivera, Beatriz

    1992-01-01

    We summarize recent work on the classification of modular invariant partition functions that can be obtained with simple currents in theories with a center (Z_p)^k with p prime. New empirical results for other centers are also presented. Our observation that the total number of invariants is monodromy-independent for (Z_p)^k appears to be true in general as well. (Talk presented in the parallel session on string theory of the Lepton-Photon/EPS Conference, Geneva, 1991.)

  17. Instant simple botting with PHP

    CERN Document Server

    Anderson, Shay Michael

    2013-01-01

    do for you, and then get to work with the most important features and tasks. This book is a hands-on Starter guide that takes the reader from initialization to the coding and implementation of bot apps.Instant Simple Botting with PHP targets programmers of all levels who are familiar with common PHP functions and syntax, and who want to learn about bots and how to design and develop bots using objects.

  18. Adverse selection without single crossing

    DEFF Research Database (Denmark)

    Schottmüller, Christoph

    2015-01-01

    The single-crossing assumption simplifies the analysis of screening models as local incentive compatibility becomes sufficient for global incentive compatibility. If single crossing is violated, global incentive compatibility constraints have to be taken into account. This paper studies monotone...... solutions in a screening model that allows a one-time violation of single crossing. The results show that local and non-local incentive constraints distort the solution in opposite directions. Therefore, the optimal decision might involve distortions above as well as below the first-best decision...

  19. Global Issues

    Energy Technology Data Exchange (ETDEWEB)

    Seitz, J.L.

    2001-10-15

    Global Issues is an introduction to the nature and background of some of the central issues - economic, social, political, environmental - of modern times. This new edition of this text has been fully updated throughout and features expanded sections on issues such as global warming, biotechnology, and energy. Fully updated throughout and features expanded sections on issues such as global warming, biotechnology, and energy. An introduction to the nature and background of some of the central issues - economic, social, political, environmental - of modern times. Covers a range of perspectives on a variety of societies, developed and developing. Extensively illustrated with diagrams and photographs, contains guides to further reading, media, and internet resources, and includes suggestions for discussion and studying the material. (author)

  20. Global Inequality

    DEFF Research Database (Denmark)

    Niño-Zarazúa, Miguel; Roope, Laurence; Tarp, Finn

    2017-01-01

    This paper measures trends in global interpersonal inequality during 1975–2010 using data from the most recent version of the World Income Inequality Database (WIID). The picture that emerges using ‘absolute,’ and even ‘centrist’ measures of inequality, is very different from the results obtained...... using standard ‘relative’ inequality measures such as the Gini coefficient or Coefficient of Variation. Relative global inequality has declined substantially over the decades. In contrast, ‘absolute’ inequality, as captured by the Standard Deviation and Absolute Gini, has increased considerably...... and unabated. Like these ‘absolute’ measures, our ‘centrist’ inequality indicators, the Krtscha measure and an intermediate Gini, also register a pronounced increase in global inequality, albeit, in the case of the latter, with a decline during 2005 to 2010. A critical question posed by our findings is whether...

  1. Global Inequality

    DEFF Research Database (Denmark)

    Niño-Zarazúa, Miguel; Roope, Laurence; Tarp, Finn

    2017-01-01

    This paper measures trends in global interpersonal inequality during 1975–2010 using data from the most recent version of the World Income Inequality Database (WIID). The picture that emerges using ‘absolute,’ and even ‘centrist’ measures of inequality, is very different from the results obtained...... by centrist measures such as the Krtscha, could return to 1975 levels, at today's domestic and global per capita income levels, but this would require quite dramatic structural reforms to reduce domestic inequality levels in most countries....... using standard ‘relative’ inequality measures such as the Gini coefficient or Coefficient of Variation. Relative global inequality has declined substantially over the decades. In contrast, ‘absolute’ inequality, as captured by the Standard Deviation and Absolute Gini, has increased considerably...

  2. Global Programs

    Science.gov (United States)

    Lindberg Christensen, Lars; Russo, P.

    2009-05-01

    IYA2009 is a global collaboration between almost 140 nations and more than 50 international organisations sharing the same vision. Besides the common brand, mission, vision and goals, IAU established eleven cornerstones programmes to support the different IYA2009 stakeholder to organize events, activities under a common umbrella. These are global activities centred on specific themes and are aligned with IYA2009's main goals. Whether it is the support and promotion of women in astronomy, the preservation of dark-sky sites around the world or educating and explaining the workings of the Universe to millions, the eleven Cornerstones are key elements in the success of IYA2009. However, the process of implementing global projects across cultural boundaries is challenging and needs central coordination to preserve the pre-established goals. During this talk we will examine the ups and downs of coordinating such a project and present an overview of the principal achievements for the Cornerstones so far.

  3. Global rotation

    International Nuclear Information System (INIS)

    Rosquist, K.

    1980-01-01

    Global rotation in cosmological models is defined on an observational basis. A theorem is proved saying that, for rigid motion, the global rotation is equal to the ordinary local vorticity. The global rotation is calculated in the space-time homogeneous class III models, with Godel's model as a special case. It is shown that, with the exception of Godel's model, the rotation in these models becomes infinite for finite affine parameter values. In some directions the rotation changes sign and becomes infinite in a direction opposite to the local vorticity. The points of infinite rotation are identified as conjugate points along the null geodesics. The physical interpretation of the infinite rotation is discussed, and a comparison with the behaviour of the area distance at conjugate points is given. (author)

  4. A simple observer of the generalized Chen chaotic systems

    International Nuclear Information System (INIS)

    Sun, Y.-J.

    2009-01-01

    In this paper, the generalized Chen chaotic system is considered and the state observation problem of such a system is investigated. Based on the time-domain approach, a simple observer for the generalized Chen chaotic system is proposed to guarantee the global exponential stability of the resulting error system. Furthermore, the guaranteed exponential convergence rate can be correctly estimated. Finally, a numerical example is provided to illustrate the use of the main result.

  5. A simple observer design of the generalized Lorenz chaotic systems

    International Nuclear Information System (INIS)

    Sun, Y.-J.

    2010-01-01

    In this Letter, the generalized Lorenz chaotic system is considered and the state observation problem of such a system is investigated. Based on the time-domain approach, a simple observer for the generalized Lorenz chaotic system is developed to guarantee the global exponential stability of the resulting error system. Moreover, the guaranteed exponential convergence rate can be correctly estimated. Finally, a numerical example is given to show the effectiveness of the obtained result.

  6. Another globalization

    Directory of Open Access Journals (Sweden)

    Prof. Ph.D. Ion Bucur

    2007-05-01

    Full Text Available Finding the anachronisms and the failures of the present globalization, as well as the vitiated system of world-wide government, has stimulated the debates regarding the identification of a more equitable form of globalization to favor the acceleration of the economic increase and the reduction of poverty.The deficiency of the present international economic institutions, especially the lack of transparency and democratic responsibility, claims back with acuteness the reformation of the architecture of the international institutional system and the promotion of those economical policies which must ensure the stability world-wide economy and the amelioration of the international equity.

  7. Going global

    International Nuclear Information System (INIS)

    Meade, W.; Poirier, J.L.

    1992-01-01

    This article discusses the global market for independent power projects and the increased competition and strategic alliances that are occurring to take advantage of the increasing demand. The topics of the article include the amount of involvement of US companies in the global market, the forces driving the market toward independent power, markets in the United Kingdom, North America, Turkey, Central America, South America, the Caribbean, Europe, the Federal Republic of Germany, India, the former Eastern European countries, Asia and the Pacific nations, and niche markets

  8. Assessment of global phase uncertainty in case-control studies

    Directory of Open Access Journals (Sweden)

    van Houwelingen Hans C

    2009-09-01

    Full Text Available Abstract Background In haplotype-based candidate gene studies a problem is that the genotype data are unphased, which results in haplotype ambiguity. The measure 1 quantifies haplotype predictability from genotype data. It is computed for each individual haplotype, and for a measure of global relative efficiency a minimum value is suggested. Alternatively, we developed methods directly based on the information content of haplotype frequency estimates to obtain global relative efficiency measures: and based on A- and D-optimality, respectively. All three methods are designed for single populations; they can be applied in cases only, controls only or the whole data. Therefore they are not necessarily optimal for haplotype testing in case-control studies. Results A new global relative efficiency measure was derived to maximize power of a simple test statistic that compares haplotype frequencies in cases and controls. Application to real data showed that our proposed method gave a clear and summarizing measure for the case-control study conducted. Additionally this measure might be used for selection of individuals, who have the highest potential for improving power by resolving phase ambiguity. Conclusion Instead of using relative efficiency measure for cases only, controls only or their combined data, we link uncertainty measure to case-control studies directly. Hence, our global efficiency measure might be useful to assess whether data are informative or have enough power for estimation of a specific haplotype risk.

  9. Single port laparoscopic surgery

    DEFF Research Database (Denmark)

    Springborg, Henrik; Istre, Olav

    2012-01-01

    LESS, or laparo-endoscopic single site surgery, is a promising new method in minimally invasive surgery. An increasing number of surgical procedures are being performed using this technique, however, its large-scale adoption awaits results of prospective randomized controlled studies confirming...... potential benefits. Theoretically, cosmetic outcomes, postoperative pain and complication rates could be improved with use of single site surgery. This study describes introduction of the method in a private hospital in Denmark, in which 40 patients have been treated for benign gynecologic conditions....... Although the operations described are the first of their kind reported in Denmark, favorable operating times and very low complication rates are seen. It is the authors' opinion that in addition to being feasible for hysterectomy, single port laparoscopy may become the preferred method for many simple...

  10. Correlation and simple linear regression.

    Science.gov (United States)

    Zou, Kelly H; Tuncali, Kemal; Silverman, Stuart G

    2003-06-01

    In this tutorial article, the concepts of correlation and regression are reviewed and demonstrated. The authors review and compare two correlation coefficients, the Pearson correlation coefficient and the Spearman rho, for measuring linear and nonlinear relationships between two continuous variables. In the case of measuring the linear relationship between a predictor and an outcome variable, simple linear regression analysis is conducted. These statistical concepts are illustrated by using a data set from published literature to assess a computed tomography-guided interventional technique. These statistical methods are important for exploring the relationships between variables and can be applied to many radiologic studies.

  11. Systems analysis made simple computerbooks

    CERN Document Server

    Antill, Lyn

    1980-01-01

    Systems Analysis: Made Simple Computerbooks introduces the essential elements of information systems analysis and design and teaches basic technical skills required for the tasks involved. The book covers the aspects to the design of an information system; information systems and the organization, including the types of information processing activity and computer-based information systems; the role of the systems analyst; and the human activity system. The text also discusses information modeling, socio-technical design, man-machine interface, and the database design. Software specification

  12. Computer electronics made simple computerbooks

    CERN Document Server

    Bourdillon, J F B

    1975-01-01

    Computer Electronics: Made Simple Computerbooks presents the basics of computer electronics and explains how a microprocessor works. Various types of PROMs, static RAMs, dynamic RAMs, floppy disks, and hard disks are considered, along with microprocessor support devices made by Intel, Motorola and Zilog. Bit slice logic and some AMD bit slice products are also described. Comprised of 14 chapters, this book begins with an introduction to the fundamentals of hardware design, followed by a discussion on the basic building blocks of hardware (NAND, NOR, AND, OR, NOT, XOR); tools and equipment that

  13. Singular perturbation of simple eigenvalues

    International Nuclear Information System (INIS)

    Greenlee, W.M.

    1976-01-01

    Two operator theoretic theorems which generalize those of asymptotic regular perturbation theory and which apply to singular perturbation problems are proved. Application of these theorems to concrete problems is involved, but the perturbation expansions for eigenvalues and eigenvectors are developed in terms of solutions of linear operator equations. The method of correctors, as well as traditional boundary layer techniques, can be used to apply these theorems. The current formulation should be applicable to highly singular ''hard core'' potential perturbations of the radial equation of quantum mechanics. The theorems are applied to a comparatively simple model problem whose analysis is basic to that of the quantum mechanical problem

  14. Simple Simulations of DNA Condensation

    Energy Technology Data Exchange (ETDEWEB)

    STEVENS,MARK J.

    2000-07-12

    Molecular dynamics simulations of a simple, bead-spring model of semiflexible polyelectrolytes such as DNA are performed. All charges are explicitly treated. Starting from extended, noncondensed conformations, condensed structures form in the simulations with tetravalent or trivalent counterions. No condensates form or are stable for divalent counterions. The mechanism by which condensates form is described. Briefly, condensation occurs because electrostatic interactions dominate entropy, and the favored Coulombic structure is a charge ordered state. Condensation is a generic phenomena and occurs for a variety of polyelectrolyte parameters. Toroids and rods are the condensate structures. Toroids form preferentially when the molecular stiffness is sufficiently strong.

  15. Wrist arthrography: a simple method

    Energy Technology Data Exchange (ETDEWEB)

    Berna-Serna, Juan D.; Reus, Manuel; Alonso, Jose [Virgen de la Arrixaca University Hospital, Department of Radiology, El Palmar (Murcia) (Spain); Martinez, Francisco; Domenech-Ratto, Gines [University of Murcia, Department of Human Anatomy, Faculty of Medicine, Murcia (Spain)

    2006-02-01

    A technique of wrist arthrography is presented using an adhesive marker-plate with radiopaque coordinates to identify precisely sites for puncture arthrography of the wrist and to obviate the need for fluoroscopic guidance. Radiocarpal joint arthrography was performed successfully in all 24 cases, 14 in the cadaveric wrists and 10 in the live patients. The arthrographic procedure described in this study is simple, safe, and rapid, and has the advantage of precise localisation of the site for puncture without need for fluoroscopic guidance. (orig.)

  16. Windows Phone 7 Made Simple

    CERN Document Server

    Trautschold, Martin

    2011-01-01

    With Windows Phone 7, Microsoft has created a completely new smartphone operating system that focuses on allowing users to be productive with their smartphone in new ways, while offering seamless integration and use of Microsoft Office Mobile as well as other productivity apps available in the Microsoft App Store. Windows Phone 7 Made Simple offers a clear, visual, step-by-step approach to using your Windows Phone 7 smartphone, no matter what the manufacturer. Author Jon Westfall is an expert in mobile devices, recognized by Microsoft as a "Most Valuable Professional" with experience

  17. Global Games

    NARCIS (Netherlands)

    van Bottenburg, Maarten

    2001-01-01

    Why is soccer the sport of choice in South America, while baseball has soared to popularity in the Carribean? How did cricket become India's national sport, while China is a stronghold of table tennis? In Global Games, Maarten van Bottenburg asserts that it is the 'hidden competition' of social and

  18. Going global?

    DEFF Research Database (Denmark)

    Fejerskov, Adam Moe; Rasmussen, Christel

    2016-01-01

    occurred at a more micro level. This article explores this issue by studying the international activities of Danish foundations. It finds that grant-making on global issues is increasing, and that several foundations have undergone transformations in their approach to grantmaking, making them surprisingly...

  19. Justice Globalism

    NARCIS (Netherlands)

    Wilson, Erin; Steger, Manfred; Siracusa, Joseph; Battersby, Paul

    2014-01-01

    The pursuit of a global order founded on universal rules extends beyond economics into the normative spheres of law, politics and justice. Justice globalists claim universal principles applicable to all societies irrespective of religion or ideology. This view privileges human rights, democracy and

  20. Brief motivational interview and educational brochure in emergency room settings for adolescents and young adults with alcohol-related problems: a randomized single-blind clinical trial Intervenção motivacional breve e brochura educacional em pronto-socorro para adolescentes e adultos jovens com problemas relacionados ao álcool: um ensaio clínico simples-cego randomizado

    Directory of Open Access Journals (Sweden)

    Maria Luiza Segatto

    2011-09-01

    Full Text Available OBJECTIVE: To evaluate the effectiveness of brief motivational interviewing and an educational brochure when delivered in emergency room to reduce alcohol abuse and related problems among adolescents and young adults. METHOD: A randomized single-blind clinical trial with a three-month follow-up was carried out at three emergency rooms from October 2004 to November 2005; subjects assessed were 16-25 years old treated for alcohol related events up to 6 hours after consumption. Socio-demographic data, quantity, frequency and negative consequences of alcohol consumption, motivation to change habits and future risk perception were evaluated. Statistical analysis was performed on subjects who completed follow-up (completers. ANCOVA model was used to analyze the difference between the intervention groups with statistical significance level α = 5% and confidence interval (CI of 95%. RESULTS: 186 subjects formed the initial sample, being 175 included and randomized to the educational brochure group (n = 88 or motivational interviewing group (n = 87. Follow-up assessment was performed in 85.2% of the sample. No significant difference between groups was observed. However, significant reductions (p OBJETIVO: Avaliar a efetividade da entrevista motivacional breve e de uma brochura educativa quando aplicadas em prontos-socorros para reduzir o abuso e problemas relacionados ao álcool entre os jovens. MÉTODO: Um ensaio clínico randomizado simples-cego com três meses de seguimento foi realizado em três prontos-socorros de outubro de 2004 a novembro de 2005, com indivíduos de 16-25 anos tratados por eventos relacionados ao álcool com até 6 horas após o consumo. Dados sociodemográficos, quantidade, frequência e consequências negativas, motivação para mudanças de hábitos e percepção para riscos do consumo de álcool foram avaliados. A análise estatística foi realizada em indivíduos que completaram o seguimento (completados. Modelo de ANCOVA

  1. Brief motivational interview and educational brochure in emergency room settings for adolescents and young adults with alcohol related problems: a randomized single blind clinical trial Intervenção motivacional breve e brochura educacional em pronto-socorro para adolescentes e adultos jovens com problemas relacionados ao álcool: um ensaio clínico simples cego randomizado

    Directory of Open Access Journals (Sweden)

    Maria Luiza Segatto

    2011-01-01

    Full Text Available OBJECTIVE: To evaluate the effectiveness of brief motivational interviewing and an educational brochure when delivered in emergency room to reduce alcohol abuse and related problems among adolescents and young adults. METHOD: a randomized single blind clinical trial with a 3 month follow-up was carried out at three emergency rooms from October 2004 to November 2005; subjects assessed were 16-25 years old treated for alcohol related events up to 6 hours after consumption. Socio-demographic data, quantity, frequency and negative consequences of alcohol consumption, motivation to change habits and future risk preception were evaluated. Statistical analysis was performed on subjects who completed follow up (completers. ANCOVA model was used to analyze the difference between the intervention groups with statistical significance level α = 5% and Confidence Interval (CI 95%. RESULTS: 186 subjects formed the initial sample, being n = 175 included and randomized to educational brochure group (n = 88 or motivational interviewing group (n = 87. Follow-up assessment was performed in 85.2% sample. No significant difference between groups was observed. However, significant reductions (p OBJETIVO: Avaliar a efetividade da entrevista motivacional breve e de uma brochura educativa quando aplicadas em prontos-socorros para reduzir o abuso e problemas relacionados ao álcool entre os jovens. MÉTODO: Um ensaio clínico randomizado simples-cego com três meses de seguimento foi realizado em três prontos-socorros de outubro de 2004 a novembro de 2005, com indivíduos de 16-25 anos tratados por eventos relacionados ao álcool com até 6 horas após o consumo. Dados sociodemográficos, quantidade, frequência e consequências negativas, motivação para mudanças de hábitos e percepção para riscos do consumo de álcool foram avaliados. A análise estatística foi realizada em indivíduos que completaram o seguimento (completados. Modelo de ANCOVA foi utilizado

  2. Efficiency, sustainability and global warming

    International Nuclear Information System (INIS)

    Woodward, Richard T.; Bishop, Richard C.

    1995-01-01

    Economic analyses of global warming have typically been grounded in the theory of economic efficiency. Such analyses may be inappropriate because many of the underlying concerns about climate change are rooted not in efficiency, but in the intergenerational allocation of economic endowments. A simple economic model is developed which demonstrates that an efficient economy is not necessarily a sustainable economy. This result leads directly to questions about the policy relevance of several economic studies of the issue. We then consider policy alternatives to address global warming in the context of economies with the dual objectives of efficiency and sustainability, with particular attention to carbon-based taxes

  3. Global swindle of global warming

    NARCIS (Netherlands)

    Zeiler, W.

    2007-01-01

    Voor sommige mensen is het nog steeds niet aannemelijk dat we te maken hebben met de effecten van ‘Global Warming’, de opwarming van de aarde door voornamelijk de broeikasgassen die vrijkomen bij de verbranding van fossiele brandstoffen. In de media worden voor- en tegenstanders aan het woord

  4. A simple mixture to enhance muscle transmittance

    Science.gov (United States)

    Oliveira, Luís; Lage, Armindo; Clemente, Manuel Pais; Tuchin, Valery V.

    2008-06-01

    Skeletal muscle is a fibrous tissue composed by muscle fibers and interstitial fluid. Due to this constitution, the muscle presents a non uniform refractive index profile that origins strong light scattering. One way to improve tissue transmittance is to reduce this refractive index mismatch by immersing the muscle in an optical clearing agent. As a consequence of such immersion tissue also suffers dehydration. The study of the optical clearing effect created by a simple mixture composed by ethanol, glycerol and distilled water has proven its effectiveness according to the variations observed in the parameters under study. The effect was characterized in terms of its magnitude, time duration and histological variations. The applied treatment has created a small reduction of the global sample refractive index that is justified by the long time rehydration caused by water in the immersing solution. From the reduction in sample pH we could also identify the dehydration process created in the sample. The immersion treatment has originated fiber bundle contraction and a spread distribution of the muscle fiber bundles inside. New studies with the mixture used, or with other combinations of its constituents might be interesting to perform with the objective to develop new clinical procedures.

  5. Conceived globals

    DEFF Research Database (Denmark)

    Cheraghi, Maryam; Schøtt, Thomas

    2016-01-01

    and culture which have separate effects. Being man, young, educated and having entrepreneurial competencies promote transnational networking extensively. Networking is embedded in culture, in the way that transnational networking is more extensive in secular-rational culture than in traditional culture.......A firm may be conceived global, in the sense that, before its birth, the founding entrepreneur has a transnational network of advisors which provides an embedding for organising the upstart that may include assembling resources and marketing abroad. The purpose is to account for the entrepreneurs...... the intending, starting and operating phases, fairly constantly with only small fluctuations. The firm is conceived global in terms of the entrepreneur's transnational networking already in the pre-birth phase, when the entrepreneur is intending to start the firm. These phase effects hardly depend on attributes...

  6. Global Derivatives

    DEFF Research Database (Denmark)

    Andersen, Torben Juul

    approaches to dealing in the global business environment." - Sharon Brown-Hruska, Commissioner, Commodity Futures Trading Commission, USA. "This comprehensive survey of modern risk management using derivative securities is a fine demonstration of the practical relevance of modern derivatives theory to risk......" provides comprehensive coverage of different types of derivatives, including exchange traded contracts and over-the-counter instruments as well as real options. There is an equal emphasis on the practical application of derivatives and their actual uses in business transactions and corporate risk...... management situations. Its key features include: derivatives are introduced in a global market perspective; describes major derivative pricing models for practical use, extending these principles to valuation of real options; practical applications of derivative instruments are richly illustrated...

  7. OMI/Aura Multi-wavelength Aerosol Optical Depth and Single Scattering Albedo Daily L2 Global 0.25x0.25 deg Lat/Lon Grid V003

    Data.gov (United States)

    National Aeronautics and Space Administration — The second release of Collection 3 OMI/Aura level-2G daily global gridded (0.25x0.25 deg) Aerosol data product OMAEROG (Version 003 has been made available to the...

  8. OMI/Aura Near UV Aerosol Optical Depth and Single Scattering Albedo Daily L2 Global 0.25x0.25 deg Lat/Lon Grid V003

    Data.gov (United States)

    National Aeronautics and Space Administration — The OMI-Aura level-2G daily global gridded (0.25x0.25 deg) near-UV Aerosol data product OMAERUVG based on the enhanced algorithm is available from the NASA Goddard...

  9. iPad Made Simple

    CERN Document Server

    Trautschold, Martin; Learning, MSL Made Simple

    2010-01-01

    The new iPad is sleek, powerful, and most importantly, it's much more than just a big iPhone. Your iPad is can be used for reading, surfing the web, emailing, watching TV/Movies, getting work done, and much more. And with the upcoming wave of iPad apps, the possibilities are endless. iPad X Made Simple clarifies all of the key features on the iPad, introduces what's new, and also reveals dozens of time-saving shortcuts and techniques. The book has over 1,000 screen shots that are carefully annotated with step-by-step instructions. * Clear instructions on how to set up and use the iPad * Illust

  10. Methadone radioimmunoassay: two simple methods

    International Nuclear Information System (INIS)

    Robinson, K.; Smith, R.N.

    1983-01-01

    Two simple and economical radioimmunoassays for methadone in blood or urine are described. Haemolysis, decomposition, common anticoagulants and sodium fluoride do not affect the results. One assay used commercially-available [1- 3 H](-)-methadone hydrobromide as the label, while the other uses a radioiodinated conjugate of 4-dimethylamino-2,2-diphenylpentanoic acid and L-tyrosine methyl ester. A commercially-available antiserum is used in both assays. Normethadone and α-methadol cross-react to a small extent with the antiserum while methadone metabolites, dextropropoxyphene, dipipanone and phenadoxone have negligible cross-reactivities. The 'cut-offs' of the two assays as described are 30 and 33 ng ml -1 for blood, and 24 and 21 ng ml -1 for urine. The assay using the radioiodinated conjugate can be made more sensitive if required by increasing the specific activity of the label. (author)

  11. Simple types of anisotropic inflation

    International Nuclear Information System (INIS)

    Barrow, John D.; Hervik, Sigbjoern

    2010-01-01

    We display some simple cosmological solutions of gravity theories with quadratic Ricci curvature terms added to the Einstein-Hilbert Lagrangian which exhibit anisotropic inflation. The Hubble expansion rates are constant and unequal in three orthogonal directions. We describe the evolution of the simplest of these homogeneous and anisotropic cosmological models from its natural initial state and evaluate the deviations they will create from statistical isotropy in the fluctuations produced during a period of anisotropic inflation. The anisotropic inflation is not a late-time attractor in these models but the rate of approach to a final isotropic de Sitter state is slow and is conducive to the creation of observable anisotropic statistical effects in the microwave background. The statistical anisotropy would not be scale invariant and the level of statistical anisotropy will grow with scale.

  12. Energy globalization

    International Nuclear Information System (INIS)

    Tierno Andres

    1997-01-01

    Toward the future, the petroleum could stop to be the main energy source in the world and the oil companies will only survive if they are adjusted to the new winds that blow in the general energy sector. It will no longer be enough to be the owner of the resource (petroleum or gas) so that a company subsists and be profitable in the long term. The future, it will depend in great measure of the vision with which the oil companies face the globalization concept that begins to experience the world in the energy sector. Concepts like globalization, competition, integration and diversification is something that the companies of the hydrocarbons sector will have very present. Globalization means that it should be been attentive to what happens in the world, beyond of the limits of its territory, or to be caught by competitive surprises that can originate in very distant places. The search of cleaner and friendlier energy sources with the means it is not the only threat that it should fear the petroleum. Their substitution for electricity in the big projects of massive transport, the technology of the communications, the optic fiber and the same relationships with the aboriginal communities are aspects that also compete with the future of the petroleum

  13. Global overeksponering

    DEFF Research Database (Denmark)

    Rosenstand, Claus A. Foss

    2007-01-01

    forandringer. Den globale orientering kommer blandt andet til udtryk i det relativt store internationale netværk, som bakker de unge op i deres protester - enten ved tilstedeværelse i København eller andre sympatiaktioner. Siden den 11. september, 2001, er globale realiteter blevet eksponeret i massemedierne...... så bliver der blændet fuldt op for linsen d. 11. september, 2001 til en global verden, hvor de demokratiske værdier ikke gælder. Lad mig blot give et eksempel: Guatanamo. Jeg skal hverken tale for eller imod den måde verden er indrettet på - da det er denne analyse uvedkommende - men blot pege på...... med væsentligt større kraft end tidligere. Før den 11. september blev globaliseringen udelukkende tegnet af jetsettet. Altså internationale politikere, kulturkoryfæer, videnskabsfolk og forretningsfolk, der har handler ud fra kendte rationaler. Men jetsettet har ikke længere den privilegeret position...

  14. Globalization – Chances or Risks

    Directory of Open Access Journals (Sweden)

    MĂDĂLINA ANTOANETA RĂDOI

    2015-05-01

    Full Text Available There are for and against arguments as regards the process of globalization. But what is globalization: a concept, a reality or a state as such? We can consider that globalization reflects the natural continuity of a process that appeared a long time ago and that has evolved ever since or a new phenomenon that was generated by the speed with which new technology and information flow. Milton Friedman, a fervent supporter of globalization, gives an answer to the question “what is globalization”; according to him, “globalization is not a simple tendency or phantasy but rather an international system. It is the new system that has replaced the Cold War system and that, like the former one, has its own laws and logic, being able to directly or indirectly influence today’s politics, the environment, geopolitics and the economy of every country in the world.” (Friedman, 2000. Globalization represents: the unlimited ascend of technology, the free flow of information, the annihilation of territorial limits, the uniformity of economy, the free flow of capital, the mobility of the person, as well as a political form of organization that aims at a future global government.

  15. Semantic markup of sensor capabilities: how simple it too simple?

    Science.gov (United States)

    Rueda-Velasquez, C. A.; Janowicz, K.; Fredericks, J.

    2016-12-01

    Semantics plays a key role for the publication, retrieval, integration, and reuse of observational data across the geosciences. In most cases, one can safely assume that the providers of such data, e.g., individual scientists, understand the observation context in which their data are collected,e.g., the used observation procedure, the sampling strategy, the feature of interest being studied, and so forth. However, can we expect that the same is true for the technical details of the used sensors and especially the nuanced changes that can impact observations in often unpredictable ways? Should the burden of annotating the sensor capabilities, firmware, operation ranges, and so forth be really part of a scientist's responsibility? Ideally, semantic annotations should be provided by the parties that understand these details and have a vested interest in maintaining these data. With manufactures providing semantically-enabled metadata for their sensors and instruments, observations could more easily be annotated and thereby enriched using this information. Unfortunately, today's sensor ontologies and tool chains developed for the Semantic Web community require expertise beyond the knowledge and interest of most manufacturers. Consequently, knowledge engineers need to better understand the sweet spot between simple ontologies/vocabularies and sufficient expressivity as well as the tools required to enable manufacturers to share data about their sensors. Here, we report on the current results of EarthCube's X-Domes project that aims to address the questions outlined above.

  16. Simple and Accurate Analytical Solutions of the Electrostatically Actuated Curled Beam Problem

    KAUST Repository

    Younis, Mohammad I.

    2014-01-01

    We present analytical solutions of the electrostatically actuated initially deformed cantilever beam problem. We use a continuous Euler-Bernoulli beam model combined with a single-mode Galerkin approximation. We derive simple analytical expressions

  17. single crystals

    Indian Academy of Sciences (India)

    2018-05-18

    May 18, 2018 ... Abstract. 4-Nitrobenzoic acid (4-NBA) single crystals were studied for their linear and nonlinear optical ... studies on the proper growth, linear and nonlinear optical ..... between the optic axes and optic sign of the biaxial crystal.

  18. Gaseous diffusion flames: simple structures and their interaction

    Energy Technology Data Exchange (ETDEWEB)

    Cavaliere, A. [Universita degli Studi Federico II, Naples (Italy). Dip. di Ingegneria Chimica; Ragucci, R. [Istituto di Ricerche sulla Combustione C,N.R., Naples (Italy)

    2001-07-01

    This is a synoptic overview of a selection of works dealing with single diffusive structures, with their mutual interaction in simple flows and their statistical modeling in complex flows. The focus is on reacting conditions pertaining to gaseous diffusion flames, but isothermal structures are also described when they are of some conceptual interest. This paper considers only few representative works for each subject, which are functional in explaining the key characteristics of the diffusive structures. The extension, given to single subjects, is not weighed according to the number of related publications but on the relevance to the basic understanding of the general framework concerning diffusion flames. One-dimensional structures are first discussed. They are ordered according to the number of balance equation terms needed for their description. Two-dimensional (2D) structures are then introduced following an order based on their convolution level. Some pioneering work on three-dimensional structures is further quoted. The temporal evolution of simple structures in quiescent or simple flowing 2D systems is considered. The latter case is exploited to present classification of diffusion-controlled mixing regimes. Modeling characterization approach of turbulent diffusion flames is also described in order to yield a self-sufficient didactic presentation. The approach based on the flame surface density model is specifically discussed because of its potential use in the determination of qualitative and quantitative features of simple diffusion flames. (author)

  19. Global safety

    Directory of Open Access Journals (Sweden)

    Dorien J. DeTombe

    2010-08-01

    Full Text Available Global Safety is a container concept referring to various threats such as HIV/Aids, floods and terrorism; threats with different causes and different effects. These dangers threaten people, the global economy and the slity of states. Policy making for this kind of threats often lack an overview of the real causes and the interventions are based on a too shallow analysis of the problem, mono-disciplinary and focus mostly only on the effects. It would be more appropriate to develop policy related to these issues by utilizing the approaches, methods and tools that have been developed for complex societal problems. Handling these complex societal problems should be done multidisciplinary instead of mono-disciplinary. In order to give politicians the opportunity to handle complex problems multidisciplinary, multidisciplinary research institutes should be created. These multidisciplinary research institutes would provide politicians with better approaches to handle this type of problem. In these institutes the knowledge necessary for the change of these problems can be created through the use of the Compram methodology which has been developed specifically for handling complex societal problems. In a six step approach, experts, actors and policymakers discuss the content of the problem and the possible changes. The framework method uses interviewing, the Group Decision Room, simulation models and scenario's in a cooperative way. The methodology emphasizes the exchange of knowledge and understanding by communication among and between the experts, actors and politicians meanwhile keeping emotion in mind. The Compram methodology will be further explained in relation to global safety in regard to terrorism, economy, health care and agriculture.

  20. Global ambitions

    International Nuclear Information System (INIS)

    Scruton, M.

    1996-01-01

    The article discusses global ambitions concerning the Norwegian petroleum industry. With the advent of the NORSOK (Forum for development and operation) cost reduction programme and a specific focus on key sectors of the market, the Norwegian oil industry is beginning to market its considerable technological achievements internationally. Obviously, the good fortune of having tested this technology in a very demanding domestic arena means that Norwegian offshore support companies, having succeeded at home, are perfectly poised to export their expertise to the international sector. Drawing on the traditional strengths of the country's maritime heritage, with mobile rig and specialized vessel business featuring strongly, other key technologies have been developed. 5 figs., 1 tab

  1. Simple substrates for complex cognition

    Directory of Open Access Journals (Sweden)

    Peter Dayan

    2008-12-01

    Full Text Available Complex cognitive tasks present a range of computational and algorithmic challenges for neural accounts of both learning and inference. In particular, it is extremely hard to solve them using the sort of simple policies that have been extensively studied as solutions to elementary Markov decision problems. There has thus been recent interest in architectures for the instantiation and even learning of policies that are formally more complicated than these, involving operations such as gated working memory. However, the focus of these ideas and methods has largely been on what might best be considered as automatized, routine or, in the sense of animal conditioning, habitual, performance. Thus, they have yet to provide a route towards understanding the workings of rule-based control, which is critical for cognitively sophisticated competence. Here, we review a recent suggestion for a uniform architecture for habitual and rule-based execution, discuss some of the habitual mechanisms that underpin the use of rules, and consider a statistical relationship between rules and habits.

  2. Plunger with simple retention valve

    International Nuclear Information System (INIS)

    Fekete, A.V.

    1987-01-01

    This patent describes a positive displacement retention valve apparatus in which the actual flow equals the theoretical maximum flow through the retention valve. The apparatus includes, in combination, a confined fluid flow conduit, a piston adapted for reciprocal movement within the fluid flow conduit between upstream and downstream limit positions, piston reciprocating means, and pressure responsive check valve means located upstream with respect to the piston in the fluid flow conduit. The pressure responsive check valve means operable to permit fluid flow therethrough in a downstream direction toward the piston, and to preclude fluid flow therethrough in an opposite direction. The piston is composed of parts which are relatively movable with respect to one another. The piston includes a simple retention valve consisting of a plug means, a cylinder having a minimum and a maximum internal cross section flow area therein and being reciprocal within the confined fluid flow conduit, and a seat on the cylinder for the plug means. The piston reciprocating means are operatively connected to the plug means

  3. Global scenarios and trends

    International Nuclear Information System (INIS)

    2011-01-01

    The 21st century brings with it a number of disturbing challenges. They may even threaten to disrupt world order. Many agree the most critical and urgent challenge of all confronting human kind today is climate change. Global warming has reached a level which can trigger drastic shifts in world weather. There is convincing evidence to show that global warming is significantly attributed to mans own activities. If man is responsible for the warming of the planet, then only man can help stop global warming. Only man can reverse climate change. Climate change has the power to literally destruct the world. The adverse effects of global climate change are increasingly evident from the frequency and ferocity of natural disasters like the recent severe drought and flood in Queensland, Australia; the prolonged drought in East Africa; the destructive typhoon Nargis in Myanmar; the terrifying hurricane Katrina which brought New Orleans to its knees; the disastrous Mississippi flood and killer cyclones in USA and the out of season drought and flood in the Yangtze river basin. The list does not end there. Dr. R. K. Pachauri, Chairman of the Intergovernmental Panel on Climate Change (IPCC), in his lecture on 28 April 2011 at UNITEN, entitled Fukushima, Energy and Climate Change reaffirmed that the warming of the earths climate system is unequivocal. That climate change is mans common enemy is no longer in doubt. This is the reason why many see climate change as the single most important driver of the expanding global interest in green technology and a low carbon economy. (author)

  4. Internationalization or globalization of higher education

    Science.gov (United States)

    Rezaei, Habibolah; Yousefi, Alireza; Larijani, Bagher; Dehnavieh, Reza; Rezaei, Nima; Adibi, Peyman

    2018-01-01

    INTRODUCTION: Studies about globalization and internationalization demonstrate different attitudes in explaining these concepts. Since there is no consensus among Iranian specialists about these concepts, the purpose of this study is to explain the concepts of internationalization and globalization in Iran. MATERIALS AND METHODS: This study is a systematic review done in the first half of 2016. To explain the concept of globalization and internationalization, articles in Scientific Information D atabase, Magiran database, and Google Scholar were searched with the keywords such as globalization, scientific exchange, international cooperation, curriculum exchange, student exchange, faculty exchange, multinational cooperation, transnational cooperation, and collaborative research. Articles, used in this study, were in Persian and were devoted to internationalization and globalization between 2001 and 2016. The criterion of discarding the articles was duplicity. RESULTS: As many as 180 Persian articles were found on this topic. After discarding repetitive articles, 64 remained. Among those, 39 articles mentioned the differences between globalization and internationalization. Definitions of globalization were categorized in four categories, including globalization, globalizing, globalization of higher education, and globalizing of higher education. Definitions about internationalization were categorized in five categories such as internationalization, internationalization of higher education, internationalization of the curriculum, internationalization of curriculum studies, and internationalization of curriculum profession. CONCLUSION: The spectrum of the globalization of higher education moves from dissonance and multipolarization to unification and single polarization of the world. One end of the spectrum, which is unification and single polarization of the world, is interpreted as globalization. The other side of the spectrum, which is dissonance and

  5. Internationalization or globalization of higher education.

    Science.gov (United States)

    Rezaei, Habibolah; Yousefi, Alireza; Larijani, Bagher; Dehnavieh, Reza; Rezaei, Nima; Adibi, Peyman

    2018-01-01

    Studies about globalization and internationalization demonstrate different attitudes in explaining these concepts. Since there is no consensus among Iranian specialists about these concepts, the purpose of this study is to explain the concepts of internationalization and globalization in Iran. This study is a systematic review done in the first half of 2016. To explain the concept of globalization and internationalization, articles in Scientific Information D atabase, Magiran database, and Google Scholar were searched with the keywords such as globalization, scientific exchange, international cooperation, curriculum exchange, student exchange, faculty exchange, multinational cooperation, transnational cooperation, and collaborative research. Articles, used in this study, were in Persian and were devoted to internationalization and globalization between 2001 and 2016. The criterion of discarding the articles was duplicity. As many as 180 Persian articles were found on this topic. After discarding repetitive articles, 64 remained. Among those, 39 articles mentioned the differences between globalization and internationalization. Definitions of globalization were categorized in four categories, including globalization, globalizing, globalization of higher education, and globalizing of higher education. Definitions about internationalization were categorized in five categories such as internationalization, internationalization of higher education, internationalization of the curriculum, internationalization of curriculum studies, and internationalization of curriculum profession. The spectrum of the globalization of higher education moves from dissonance and multipolarization to unification and single polarization of the world. One end of the spectrum, which is unification and single polarization of the world, is interpreted as globalization. The other side of the spectrum, which is dissonance and multipolarization, is interpreted as globalizing. The definition of

  6. Expectations for inflationary observables: simple or natural?

    Science.gov (United States)

    Musoke, Nathan; Easther, Richard

    2017-12-01

    We describe the general inflationary dynamics that can arise with a single, canonically coupled field where the inflaton potential is a 4-th order polynomial. This scenario yields a wide range of combinations of the empirical spectral observables, ns, r and αs. However, not all combinations are possible and next-generation cosmological experiments have the ability to rule out all inflationary scenarios based on this potential. Further, we construct inflationary priors for this potential based on physically motivated choices for its free parameters. These can be used to determine the degree of tuning associated with different combinations of ns, r and αs and will facilitate treatments of the inflationary model selection problem. Finally, we comment on the implications of these results for the naturalness of the overall inflationary paradigm. We argue that ruling out all simple, renormalizable potentials would not necessarily imply that the inflationary paradigm itself was unnatural, but that this eventuality would increase the importance of building inflationary scenarios in the context of broader paradigms of ultra-high energy physics.

  7. Entanglement in a simple quantum phase transition

    International Nuclear Information System (INIS)

    Osborne, Tobias J.; Nielsen, Michael A.

    2002-01-01

    What entanglement is present in naturally occurring physical systems at thermal equilibrium? Most such systems are intractable and it is desirable to study simple but realistic systems that can be solved. An example of such a system is the one-dimensional infinite-lattice anisotropic XY model. This model is exactly solvable using the Jordan-Wigner transform, and it is possible to calculate the two-site reduced density matrix for all pairs of sites. Using the two-site density matrix, the entanglement of formation between any two sites is calculated for all parameter values and temperatures. We also study the entanglement in the transverse Ising model, a special case of the XY model, which exhibits a quantum phase transition. It is found that the next-nearest-neighbor entanglement (though not the nearest-neighbor entanglement) is a maximum at the critical point. Furthermore, we show that the critical point in the transverse Ising model corresponds to a transition in the behavior of the entanglement between a single site and the remainder of the lattice

  8. ZeroMQ: Messaging Made Simple

    CERN Multimedia

    CERN. Geneva

    2013-01-01

    Since its inception in 2007, ZeroMQ has defined a new product category of thin, fast, open source message transports. This little library has now grown into a large, vibrant community of projects tied together with standard protocols and APIs. Applications, written in any language, talk to each other over TCP, multicast, or inproc transports, using a single socket-based API, and a set of "patterns" (pub-sub, request-reply, dealer-router, pipeline). ZeroMQ handles message framing, batching, and I/O, but ignores aspects like serialization and persistence. By focussing on the essentials, and acting as a toolkit rather than a pre-packaged solution, ZeroMQ turns the complex problem of distributed computing into a relatively simple recipe. About the speaker Pieter Hintjens is a writer, programmer, and public speaker who has spent decades building large software systems, organizations, and businesses. He designed the Advanced Message Queuing Protocol (AMQP) in 2006 for JPMorganChase and left ...

  9. Global health and global health ethics

    National Research Council Canada - National Science Library

    Benatar, S. R; Brock, Gillian

    2011-01-01

    ...? What are our responsibilities and how can we improve global health? Global Health and Global Health Ethics addresses these questions from the perspective of a range of disciplines, including medicine, philosophy and the social sciences...

  10. Renormalization group analysis of a simple hierarchical fermion model

    International Nuclear Information System (INIS)

    Dorlas, T.C.

    1991-01-01

    A simple hierarchical fermion model is constructed which gives rise to an exact renormalization transformation in a 2-dimensional parameter space. The behaviour of this transformation is studied. It has two hyperbolic fixed points for which the existence of a global critical line is proven. The asymptotic behaviour of the transformation is used to prove the existence of the thermodynamic limit in a certain domain in parameter space. Also the existence of a continuum limit for these theories is investigated using information about the asymptotic renormalization behaviour. It turns out that the 'trivial' fixed point gives rise to a two-parameter family of continuum limits corresponding to that part of parameter space where the renormalization trajectories originate at this fixed point. Although the model is not very realistic it serves as a simple example of the appliclation of the renormalization group to proving the existence of the thermodynamic limit and the continuum limit of lattice models. Moreover, it illustrates possible complications that can arise in global renormalization group behaviour, and that might also be present in other models where no global analysis of the renormalization transformation has yet been achieved. (orig.)

  11. SSL - THE SIMPLE SOCKETS LIBRARY

    Science.gov (United States)

    Campbell, C. E.

    1994-01-01

    The Simple Sockets Library (SSL) allows C programmers to develop systems of cooperating programs using Berkeley streaming Sockets running under the TCP/IP protocol over Ethernet. The SSL provides a simple way to move information between programs running on the same or different machines and does so with little overhead. The SSL can create three types of Sockets: namely a server, a client, and an accept Socket. The SSL's Sockets are designed to be used in a fashion reminiscent of the use of FILE pointers so that a C programmer who is familiar with reading and writing files will immediately feel comfortable with reading and writing with Sockets. The SSL consists of three parts: the library, PortMaster, and utilities. The user of the SSL accesses it by linking programs to the SSL library. The PortMaster initializes connections between clients and servers. The PortMaster also supports a "firewall" facility to keep out socket requests from unapproved machines. The "firewall" is a file which contains Internet addresses for all approved machines. There are three utilities provided with the SSL. SKTDBG can be used to debug programs that make use of the SSL. SPMTABLE lists the servers and port numbers on requested machine(s). SRMSRVR tells the PortMaster to forcibly remove a server name from its list. The package also includes two example programs: multiskt.c, which makes multiple accepts on one server, and sktpoll.c, which repeatedly attempts to connect a client to some server at one second intervals. SSL is a machine independent library written in the C-language for computers connected via Ethernet using the TCP/IP protocol. It has been successfully compiled and implemented on a variety of platforms, including Sun series computers running SunOS, DEC VAX series computers running VMS, SGI computers running IRIX, DECstations running ULTRIX, DEC alpha AXPs running OSF/1, IBM RS/6000 computers running AIX, IBM PC and compatibles running BSD/386 UNIX and HP Apollo 3000

  12. Reconstructing Nearly Simple Polytopes from their Graph

    OpenAIRE

    Doolittle, Joseph

    2017-01-01

    We present a partial description of which polytopes are reconstructible from their graphs. This is an extension of work by Blind and Mani (1987) and Kalai (1988), which showed that simple polytopes can be reconstructed from their graphs. In particular, we introduce a notion of $h$-nearly simple and prove that 1-nearly simple and 2-nearly simple polytopes are reconstructible from their graphs. We also give an example of a 3-nearly simple polytope which is not reconstructible from its graph. Fu...

  13. Global teaching of global seismology

    Science.gov (United States)

    Stein, S.; Wysession, M.

    2005-12-01

    Our recent textbook, Introduction to Seismology, Earthquakes, & Earth Structure (Blackwell, 2003) is used in many countries. Part of the reason for this may be our deliberate attempt to write the book for an international audience. This effort appears in several ways. We stress seismology's long tradition of global data interchange. Our brief discussions of the science's history illustrate the contributions of scientists around the world. Perhaps most importantly, our discussions of earthquakes, tectonics, and seismic hazards take a global view. Many examples are from North America, whereas others are from other areas. Our view is that non-North American students should be exposed to North American examples that are type examples, and that North American students should be similarly exposed to examples elsewhere. For example, we illustrate how the Euler vector geometry changes a plate boundary from spreading, to strike-slip, to convergence using both the Pacific-North America boundary from the Gulf of California to Alaska and the Eurasia-Africa boundary from the Azores to the Mediterranean. We illustrate diffuse plate boundary zones using western North America, the Andes, the Himalayas, the Mediterranean, and the East Africa Rift. The subduction zone discussions examine Japan, Tonga, and Chile. We discuss significant earthquakes both in the U.S. and elsewhere, and explore hazard mitigation issues in different contexts. Both comments from foreign colleagues and our experience lecturing overseas indicate that this approach works well. Beyond the specifics of our text, we believe that such a global approach is facilitated by the international traditions of the earth sciences and the world youth culture that gives students worldwide common culture. For example, a video of the scene in New Madrid, Missouri that arose from a nonsensical earthquake prediction in 1990 elicits similar responses from American and European students.

  14. Globalizing Denmark

    DEFF Research Database (Denmark)

    Selmer, Jan; Lauring, Jakob

    2013-01-01

    countries to keep up the process of globalization may be substantial, and the economic gains for such countries from adjusting to a more internationally integrated world economy are clear. However, in small- population economies, especially social-democratic welfare states, the internal pressure......This exploratory article examines the paradox of being open-minded while ethnocentric as expressed in Danish international management practices at the micro level. With a population of 5.4 million, Denmark is one of the smallest of the European countries. The pressure on many small advanced...... to integrate counteracts to some extent the need to maintain openness to differences. Thus, a strong economy and a feeling of smug ethnocentrism in Denmark generate a central paradox in thinking about internationalization in Danish society....

  15. Global engineering

    International Nuclear Information System (INIS)

    Plass, L.

    2001-01-01

    This article considers the challenges posed by the declining orders in the plant engineering and contracting business in Germany, the need to remain competitive, and essential preconditions for mastering the challenge. The change in engineering approach is illustrated by the building of a methanol plant in Argentina by Lurgi with the basic engineering completed in Frankfurt with involvement of key personnel from Poland, completely engineered subsystems from a Brazilian subsupplier, and detailed engineering work in Frankfurt. The production of methanol from natural gas using the LurgiMega/Methanol process is used as a typical example of the industrial plant construction sector. The prerequisites for successful global engineering are listed, and error costs in plant construction, possible savings, and process intensification are discussed

  16. Global warming

    International Nuclear Information System (INIS)

    Houghton, John

    2005-01-01

    'Global warming' is a phrase that refers to the effect on the climate of human activities, in particular the burning of fossil fuels (coal, oil and gas) and large-scale deforestation, which cause emissions to the atmosphere of large amounts of 'greenhouse gases', of which the most important is carbon dioxide. Such gases absorb infrared radiation emitted by the Earth's surface and act as blankets over the surface keeping it warmer than it would otherwise be. Associated with this warming are changes of climate. The basic science of the 'greenhouse effect' that leads to the warming is well understood. More detailed understanding relies on numerical models of the climate that integrate the basic dynamical and physical equations describing the complete climate system. Many of the likely characteristics of the resulting changes in climate (such as more frequent heat waves, increases in rainfall, increase in frequency and intensity of many extreme climate events) can be identified. Substantial uncertainties remain in knowledge of some of the feedbacks within the climate system (that affect the overall magnitude of change) and in much of the detail of likely regional change. Because of its negative impacts on human communities (including for instance substantial sea-level rise) and on ecosystems, global warming is the most important environmental problem the world faces. Adaptation to the inevitable impacts and mitigation to reduce their magnitude are both necessary. International action is being taken by the world's scientific and political communities. Because of the need for urgent action, the greatest challenge is to move rapidly to much increased energy efficiency and to non-fossil-fuel energy sources

  17. Global gamesmanship.

    Science.gov (United States)

    MacMillan, Ian C; van Putten, Alexander B; McGrath, Rita Gunther

    2003-05-01

    Competition among multinationals these days is likely to be a three-dimensional game of global chess: The moves an organization makes in one market are designed to achieve goals in another in ways that aren't immediately apparent to its rivals. The authors--all management professors-call this approach "competing under strategic interdependence," or CSI. And where this interdependence exists, the complexity of the situation can quickly overwhelm ordinary analysis. Indeed, most business strategists are terrible at anticipating the consequences of interdependent choices, and they're even worse at using interdependency to their advantage. In this article, the authors offer a process for mapping the competitive landscape and anticipating how your company's moves in one market can influence its competitive interactions in others. They outline the six types of CSI campaigns--onslaughts, contests, guerrilla campaigns, feints, gambits, and harvesting--available to any multiproduct or multimarket corporation that wants to compete skillfully. They cite real-world examples such as the U.S. pricing battle Philip Morris waged with R.J. Reynolds--not to gain market share in the domestic cigarette market but to divert R.J. Reynolds's resources and attention from the opportunities Philip Morris was pursuing in Eastern Europe. And, using data they collected from their studies of consumer-products companies Procter & Gamble and Unilever, the authors describe how to create CSI tables and bubble charts that present a graphical look at the competitive landscape and that may uncover previously hidden opportunities. The CSI mapping process isn't just for global corporations, the authors explain. Smaller organizations that compete with a portfolio of products in just one national or regional market may find it just as useful for planning their next business moves.

  18. Refrigeration and global warming

    International Nuclear Information System (INIS)

    Anon.

    1997-01-01

    Some aspects of global warming in general, and the implications for refrigerants and refrigerator efficiency in particular, are briefly considered in a question and answer format. The concepts of Global Warming Potential (GWP) and Total Equivalent Warming Impact (TEWI) are explained. GWP is an index which allows a simple comparison to be make between the warming effects of different gases on a kg to kg basis relative to carbon. The GWP depends both on the lifetime of a substance in the atmosphere and its infra-red absorption capacity. The overall warming effect of operating a refrigeration system for its entire life is measured by its TEWI. Chloroflourocarbons (CFCs) which have been widely used as refrigerants are powerful greenhouse gases with high GWPs. Because of the bank of CFCs in refrigerating systems, their levels in the atmosphere are still increasing and it will be some time before refrigerant changes will be effective in reducing the warming effects of refrigerant releases. Hydrocarbons, hydroflourocarbons and ammonia all have a part to play as substitute refrigerants. Refrigerator efficiency is very important in terms of reducing CO 2 emissions. (UK)

  19. Interaction dynamics of multiple mobile robots with simple navigation strategies

    Science.gov (United States)

    Wang, P. K. C.

    1989-01-01

    The global dynamic behavior of multiple interacting autonomous mobile robots with simple navigation strategies is studied. Here, the effective spatial domain of each robot is taken to be a closed ball about its mass center. It is assumed that each robot has a specified cone of visibility such that interaction with other robots takes place only when they enter its visibility cone. Based on a particle model for the robots, various simple homing and collision-avoidance navigation strategies are derived. Then, an analysis of the dynamical behavior of the interacting robots in unbounded spatial domains is made. The article concludes with the results of computer simulations studies of two or more interacting robots.

  20. 10 rules for managing global innovation.

    Science.gov (United States)

    Wilson, Keeley; Doz, Yves L

    2012-10-01

    More and more companies recognize that their dispersed, global operations are a treasure trove of ideas and capabilities for innovation. But it's proving harder than expected to unearth those ideas or exploit those capabilities. Part of the problem is that companies manage global innovation the same way they manage traditional, single-location projects. Single-location projects draw on a large reservoir of tacit knowledge, shared context, and trust that global projects lack. The management challenge, therefore, is to replicate the positive aspects of colocation while harnessing the opportunities of dispersion. In this article, Insead's Wilson and Doz draw on research into global strategy and innovation to present a set of guidelines for setting up and managing global innovation. They explore in detail the challenges that make global projects inherently different and show how these can be overcome by applying superior project management skills across teams, fostering a strong collaborative culture, and using a robust array of communications tools.

  1. Globalization, Credence Goods and International Civil Society

    OpenAIRE

    Krautheim, Sebastian; Verdier, Thierry

    2012-01-01

    The process of globalization is characterized by an impressive growth in global value chains, as well as the proliferation of non-governmental organizations (NGOs) interacting with production and sourcing decisions of multinational firms. In this paper, we present a simple North-South model of international trade allowing for the joint emergence of firm offshoring to South and NGO activism financed by donations from the civil society. In our model northern consumers care about unobservable “c...

  2. Climate stability and sensitivity in some simple conceptual models

    Energy Technology Data Exchange (ETDEWEB)

    Bates, J. Ray [University College Dublin, Meteorology and Climate Centre, School of Mathematical Sciences, Dublin (Ireland)

    2012-02-15

    A theoretical investigation of climate stability and sensitivity is carried out using three simple linearized models based on the top-of-the-atmosphere energy budget. The simplest is the zero-dimensional model (ZDM) commonly used as a conceptual basis for climate sensitivity and feedback studies. The others are two-zone models with tropics and extratropics of equal area; in the first of these (Model A), the dynamical heat transport (DHT) between the zones is implicit, in the second (Model B) it is explicitly parameterized. It is found that the stability and sensitivity properties of the ZDM and Model A are very similar, both depending only on the global-mean radiative response coefficient and the global-mean forcing. The corresponding properties of Model B are more complex, depending asymmetrically on the separate tropical and extratropical values of these quantities, as well as on the DHT coefficient. Adopting Model B as a benchmark, conditions are found under which the validity of the ZDM and Model A as climate sensitivity models holds. It is shown that parameter ranges of physical interest exist for which such validity may not hold. The 2 x CO{sub 2} sensitivities of the simple models are studied and compared. Possible implications of the results for sensitivities derived from GCMs and palaeoclimate data are suggested. Sensitivities for more general scenarios that include negative forcing in the tropics (due to aerosols, inadvertent or geoengineered) are also studied. Some unexpected outcomes are found in this case. These include the possibility of a negative global-mean temperature response to a positive global-mean forcing, and vice versa. (orig.)

  3. Combining p-values in replicated single-case experiments with multivariate outcome.

    Science.gov (United States)

    Solmi, Francesca; Onghena, Patrick

    2014-01-01

    Interest in combining probabilities has a long history in the global statistical community. The first steps in this direction were taken by Ronald Fisher, who introduced the idea of combining p-values of independent tests to provide a global decision rule when multiple aspects of a given problem were of interest. An interesting approach to this idea of combining p-values is the one based on permutation theory. The methods belonging to this particular approach exploit the permutation distributions of the tests to be combined, and use a simple function to combine probabilities. Combining p-values finds a very interesting application in the analysis of replicated single-case experiments. In this field the focus, while comparing different treatments effects, is more articulated than when just looking at the means of the different populations. Moreover, it is often of interest to combine the results obtained on the single patients in order to get more global information about the phenomenon under study. This paper gives an overview of how the concept of combining p-values was conceived, and how it can be easily handled via permutation techniques. Finally, the method of combining p-values is applied to a simulated replicated single-case experiment, and a numerical illustration is presented.

  4. Singled out?

    Science.gov (United States)

    Waller, Frank

    2004-03-01

    The increasing use of single use medical devices is being driven by a growing awareness of iatrogenic (from the Greek; caused by the doctor) and nosocomial infections. Public health perceptions relating to transmissible spongiform encephalopathies, specifically variant Creutzfeldt-Jakob disease (vCJD), the Human Immunodeficiency Virus (HIV) and Hepatitis B are high on the political agenda and a matter of concern to healthcare professionals.

  5. A simple method for multiday imaging of slice cultures.

    Science.gov (United States)

    Seidl, Armin H; Rubel, Edwin W

    2010-01-01

    The organotypic slice culture (Stoppini et al. A simple method for organotypic cultures of nervous tissue. 1991;37:173-182) has become the method of choice to answer a variety of questions in neuroscience. For many experiments, however, it would be beneficial to image or manipulate a slice culture repeatedly, for example, over the course of many days. We prepared organotypic slice cultures of the auditory brainstem of P3 and P4 mice and kept them in vitro for up to 4 weeks. Single cells in the auditory brainstem were transfected with plasmids expressing fluorescent proteins by way of electroporation (Haas et al. Single-cell electroporation for gene transfer in vivo. 2001;29:583-591). The culture was then placed in a chamber perfused with oxygenated ACSF and the labeled cell imaged with an inverted wide-field microscope repeatedly for multiple days, recording several time-points per day, before returning the slice to the incubator. We describe a simple method to image a slice culture preparation during the course of multiple days and over many continuous hours, without noticeable damage to the tissue or photobleaching. Our method uses a simple, inexpensive custom-built insulator constructed around the microscope to maintain controlled temperature and uses a perfusion chamber as used for in vitro slice recordings. (c) 2009 Wiley-Liss, Inc.

  6. Global economic processes and Ukraine

    Directory of Open Access Journals (Sweden)

    Svitlana Radzievska

    2014-02-01

    Full Text Available The paper presents main trends in global economic development and impact thereof on Ukraine. A characteristic feature of the contemporary world is acceleration of globalization caused by achievements of the scientific and technological progress, which have provided technical means for successful overcoming the factors of time and space, whereby making the world more compact and ensuring the possibility of functioning as a single economic mechanism. Growing of opportunities for solving global problems is accompanied by aggravation of the latter such as: population growth, depletion of natural resources, deterioration of the environment, the mounting danger of climatic changes, potential failure to provide people with foods and potable water. Growth of social inequality in the world is also observed, as is increased differentiation of population by income level, which intensifies migration processes and thereby creates new problems related to coexistence of people belonging to different civilizations, cultures and value systems. An integral part of globalization is formation of regional associations which requires Ukraine to participate in this phase of globalization by means of becoming a member of a regional integration association with the purpose of improving its competitiveness and ensuring decent living for Ukrainian people under conditions of humanity functioning as a single planetary organism

  7. Transfer of Training in Simple Addition.

    Science.gov (United States)

    Chen, Yalin; Campbell, Jamie I D

    2017-04-18

    In recent years several researchers have proposed that skilled adults may solve single-digit addition problems (e.g. 3 + 1 = 4, 4 + 3 = 7) using a fast counting procedure. Practicing a procedure, often leads to transfer of learning and faster performance of unpracticed items. Such transfer has been demonstrated using a counting-based alphabet arithmetic task (e.g., B + 4 = C D E F) that indicated robust generalization of practice (i.e., RT gains) when untrained transfer problems at test had been implicitly practiced (e.g., practice B + 3, test B + 2 or B + 1). Here we constructed analogous simple addition problems (practice 4 + 3, test 4 + 2 or 4 + 1). In each of three experiments (total n = 108) participants received six practice blocks followed by two test blocks of new problems to examine generalization effects. Practice of addition identity-rule problems (i.e., 0 + N = N) showed complete transfer of RT gains made during practice to unpracticed items at test. In contrast, the addition ties (2 + 2, 3 + 3, etc.) presented large RT costs for unpracticed problems at test, but sped up substantially in the second test block. This pattern is consistent with item-specific strengthening of associative memory. The critical items were small non-tie additions (sum ≤ 10) for which the test problems would be implicitly practiced if counting was employed during practice. In all three experiments (and collectively) there was no evidence of generalization for these items in the first test block, but there was robust speed up when the items were repeated in the second test block. Thus, there was no evidence of the generalization of practice that would be expected if counting procedures mediated our participants' performance on small non-tie addition problems.

  8. Global challenges

    International Nuclear Information System (INIS)

    Blix, H.

    1990-01-01

    A major challenge now facing the world is the supply of energy needed for growth and development in a manner which is not only economically viable but also environmentally acceptable and sustainable in view of the demands of and risks to future generations. The internationally most significant pollutants from energy production through fossil fuels are SO 2 and NO x which cause acid rain, and CO 2 which is the most significant contributor to the greenhouse effect. Nuclear power, now providing about 17% of the world's electricity and 5% of the primary energy already is making a notable contribution to avoiding these emissions. While the industrialized countries will need more energy and especially electricity in the future, the needs of the developing countries are naturally much larger and present a tremendous challenge to the shaping of the world's future energy supply system. The advanced countries will have to accept special responsibilities, as they can most easily use advanced technologies and they have been and remain the main contributors to the environmental problems we now face. Energy conservation and resort to new renewable energy sources, though highly desirable, appear inadequate alone to meet the challenges. The world can hardly afford to do without an increased use of nuclear power, although it is strongly contested in many countries. The objections raised against the nuclear option focus on safety, waste management and disposal problems and the risk for proliferation of nuclear weapons. These issues are not without their problems. The risk of proliferation exists but will not appreciably diminish with lesser global reliance on nuclear power. The waste issue is more of a political than a technical problem. The use of nuclear power, or any other energy source, will never be at zero risk, but the risks are constantly reduced by new techniques and practices. The IAEA sees it as one of its priority tasks to promote such techniques. (author)

  9. Simple Impeller Systems for Maintenance of Oil Palm Culture Aggregates

    International Nuclear Information System (INIS)

    Tarmizi, A.H.; Zaiton, R.; Rosli, M.Y.

    2016-01-01

    Scaling up of liquid culture systems generally involves moving from the use of simple shake flasks to bioreactors or specialised vessels; this is costly. A new innovation called the Two-in-One MPOB Simple Impeller (2-in-1 MoSLIM) was developed using commonly available Schott bottles in the laboratory. This system provided simultaneous aeration and agitation (two-in-one) in a single device for tissue propagation in liquid culture. The 2-in-1 MoSLIM produced cell aggregates with fresh weight increments of two- to six-fold over 30-40 days. This system was a convenient alternative compared to the conventional shake flask system. Multiplication of cultures in the 2-in-1 MoSLIM did not require any shaker or a big space area. This system with a working volume of 300 - 700 ml used a simple impeller and a pump for agitation and aeration purposes. However, with the 2-in-1 MoSLIM, media replenishment remained a tedious task. To overcome this, modifications were made to the system to enable media replenishment on-site without the need of a sterile hood. The adaptation of 2-in-1 MoSLIM with an earlier innovation, Fast Transfer Technique (MoFaTT) in Liquid Culture System, resulted in the development of the Simple Impeller with Fast Transfer Technique (SLIM-FaTT) system. This new system can be applied to the liquid culture system of any crop with a potential towards automation. (author)

  10. Integrin Beta 1 Suppresses Multilayering of a Simple Epithelium

    Science.gov (United States)

    Chen, Jichao; Krasnow, Mark A.

    2012-01-01

    Epithelia are classified as either simple, a single cell layer thick, or stratified (multilayered). Stratified epithelia arise from simple epithelia during development, and transcription factor p63 functions as a key positive regulator of epidermal stratification. Here we show that deletion of integrin beta 1 (Itgb1) in the developing mouse airway epithelium abrogates airway branching and converts this monolayer epithelium into a multilayer epithelium with more than 10 extra layers. Mutant lung epithelial cells change mitotic spindle orientation to seed outer layers, and cells in different layers become molecularly and functionally distinct, hallmarks of normal stratification. However, mutant lung epithelial cells do not activate p63 and do not switch to the stratified keratin profile of epidermal cells. These data, together with previous data implicating Itgb1 in regulation of epidermal stratification, suggest that the simple-versus-stratified developmental decision may involve not only stratification inducers like p63 but suppressors like Itgb1 that prevent simple epithelia from inappropriately activating key steps in the stratification program. PMID:23285215

  11. Learning Global-Local Distance Metrics for Signature-Based Biometric Cryptosystems

    Directory of Open Access Journals (Sweden)

    George S. Eskander Ekladious

    2017-11-01

    Full Text Available Biometric traits, such as fingerprints, faces and signatures have been employed in bio-cryptosystems to secure cryptographic keys within digital security schemes. Reliable implementations of these systems employ error correction codes formulated as simple distance thresholds, although they may not effectively model the complex variability of behavioral biometrics like signatures. In this paper, a Global-Local Distance Metric (GLDM framework is proposed to learn cost-effective distance metrics, which reduce within-class variability and augment between-class variability, so that simple error correction thresholds of bio-cryptosystems provide high classification accuracy. First, a large number of samples from a development dataset are used to train a global distance metric that differentiates within-class from between-class samples of the population. Then, once user-specific samples are available for enrollment, the global metric is tuned to a local user-specific one. Proof-of-concept experiments on two reference offline signature databases confirm the viability of the proposed approach. Distance metrics are produced based on concise signature representations consisting of about 20 features and a single prototype. A signature-based bio-cryptosystem is designed using the produced metrics and has shown average classification error rates of about 7% and 17% for the PUCPR and the GPDS-300 databases, respectively. This level of performance is comparable to that obtained with complex state-of-the-art classifiers.

  12. Some Einstein spaces and their global properties

    International Nuclear Information System (INIS)

    Siklos, S.T.C.

    1981-01-01

    The global structure of a class of Einstein spaces is investigated. These spaces have algebraically special Weyl tensors and contain homogeneous hypersurfaces. It is found that they display simple examples of a variety of interesting configuration involving horizons and singularities. (author)

  13. Local smoothness for global optical flow

    DEFF Research Database (Denmark)

    Rakêt, Lars Lau

    2012-01-01

    by this technique and work on local-global optical flow we propose a simple method for fusing optical flow estimates of different smoothness by evaluating interpolation quality locally by means of L1 block match on the corresponding set of gradient images. We illustrate the method in a setting where optical flows...

  14. Does trade liberalization increase global pollution?

    International Nuclear Information System (INIS)

    Beladi, Hamid; Oladi, Reza

    2011-01-01

    In this paper we consider a simple duopoly market in which a home firm and a foreign firm use labor to produce an identical product and supply it to the home market. Firms emit pollution as a by-product of production. We show conditions under which international trade liberalization decreases (increases) the global pollution. (author)

  15. Simple sorting algorithm test based on CUDA

    OpenAIRE

    Meng, Hongyu; Guo, Fangjin

    2015-01-01

    With the development of computing technology, CUDA has become a very important tool. In computer programming, sorting algorithm is widely used. There are many simple sorting algorithms such as enumeration sort, bubble sort and merge sort. In this paper, we test some simple sorting algorithm based on CUDA and draw some useful conclusions.

  16. The Fluid Foil: The Seventh Simple Machine

    Science.gov (United States)

    Mitts, Charles R.

    2012-01-01

    A simple machine does one of two things: create a mechanical advantage (lever) or change the direction of an applied force (pulley). Fluid foils are unique among simple machines because they not only change the direction of an applied force (wheel and axle); they convert fluid energy into mechanical energy (wind and Kaplan turbines) or vice versa,…

  17. Simple utility functions with Giffen demand

    DEFF Research Database (Denmark)

    Sørensen, Peter Norman

    2007-01-01

    Simple utility functions with the Giffen property are presented: locally, the demand curve for a good is upward sloping. The utility functions represent continuous, monotone, convex preferences......Simple utility functions with the Giffen property are presented: locally, the demand curve for a good is upward sloping. The utility functions represent continuous, monotone, convex preferences...

  18. Falling balls and simple shearing strain

    International Nuclear Information System (INIS)

    Brun, J L; Pacheco, A F

    2006-01-01

    The problem of particles falling under gravity allows us to relate Hamiltonian mechanics to such different subjects as elasticity and fluid mechanics. It is with this in mind that mechanics gives us the opportunity of introducing, in a rather simple and unusual form, some concepts such as vorticity, the incompressibility condition or simple shear strain to physics students at the undergraduate level

  19. Simple clamped connection for bamboo truss systems

    NARCIS (Netherlands)

    Blok, R.

    2016-01-01

    “How to make fast and simple tension connections for truss systems?” The Solution: The innovation is a connection that uses only widely available base components (boltsand threaded steel bars) and simple hand tools to install it. With a handsaw and aspanner, the bamboo stems can be combined into to

  20. NVU perspective on simple liquids’ quasiuniversality

    DEFF Research Database (Denmark)

    Dyre, J. C.

    2013-01-01

    The last half-century of research into the structure, dynamics, and thermodynamics of simple liquids has revealed a number of approximate universalities. This paper argues that simple liquids' reduced-coordinate constant-potential-energy hypersurfaces constitute a quasiuniversal family of compact...

  1. A simple approach to nonlinear oscillators

    International Nuclear Information System (INIS)

    Ren Zhongfu; He Jihuan

    2009-01-01

    A very simple and effective approach to nonlinear oscillators is suggested. Anyone with basic knowledge of advanced calculus can apply the method to finding approximately the amplitude-frequency relationship of a nonlinear oscillator. Some examples are given to illustrate its extremely simple solution procedure and an acceptable accuracy of the obtained solutions.

  2. Sporadic simple groups and quotient singularities

    International Nuclear Information System (INIS)

    Cheltsov, I A; Shramov, C A

    2013-01-01

    We show that if a faithful irreducible representation of a central extension of a sporadic simple group with centre contained in the commutator subgroup gives rise to an exceptional (resp. weakly exceptional but not exceptional) quotient singularity, then that simple group is the Hall-Janko group (resp. the Suzuki group)

  3. A simple model of HIV epidemic in Italy: The role of the antiretroviral treatment.

    Science.gov (United States)

    Papa, Federico; Binda, Francesca; Felici, Giovanni; Franzetti, Marco; Gandolfi, Alberto; Sinisgalli, Carmela; Balotta, Claudia

    2018-02-01

    In the present paper we propose a simple time-varying ODE model to describe the evolution of HIV epidemic in Italy. The model considers a single population of susceptibles, without distinction of high-risk groups within the general population, and accounts for the presence of immigration and emigration, modelling their effects on both the general demography and the dynamics of the infected subpopulations. To represent the intra-host disease progression, the untreated infected population is distributed over four compartments in cascade according to the CD4 counts. A further compartment is added to represent infected people under antiretroviral therapy. The per capita exit rate from treatment, due to voluntary interruption or failure of therapy, is assumed variable with time. The values of the model parameters not reported in the literature are assessed by fitting available epidemiological data over the decade 2003÷2012. Predictions until year 2025 are computed, enlightening the impact on the public health of the early initiation of the antiretroviral therapy. The benefits of this change in the treatment eligibility consist in reducing the HIV incidence rate, the rate of new AIDS cases, and the rate of death from AIDS. Analytical results about properties of the model in its time-invariant form are provided, in particular the global stability of the equilibrium points is established either in the absence and in the presence of infected among immigrants.

  4. Influence of dose rate on the induction of simple and complex chromosome exchanges by gamma rays.

    Science.gov (United States)

    Loucas, Bradford D; Eberle, Richard; Bailey, Susan M; Cornforth, Michael N

    2004-10-01

    Single-color painting of whole chromosomes, or protocols in which only a few chromosomes are distinctively painted, will always fail to detect a proportion of complex exchanges because they frequently produce pseudosimple painting patterns that are indistinguishable from those produced by bona fide simple exchanges. When 24-color multi-fluor FISH (mFISH) was employed for the purpose of distinguishing (truly) simple from pseudosimple exchanges, it was confirmed that the acute low-LET radiation dose-response relationship for simple exchanges lacked significant upward curvature. This result has been interpreted to indicate that the formation of simple exchanges requires only one chromosome locus be damaged (e.g. broken) by radiation to initiate an exchange-not two, as classical cytogenetic theory maintains. Because a one-lesion mechanism implies single-track action, it follows that the production of simple exchanges should not be influenced by changes in dose rate. To examine this prediction, we irradiated noncycling primary human fibroblasts with graded doses of (137)Cs gamma rays at an acute dose rate of 1.10 Gy/min and compared, using mFISH, the yield of simple exchanges to that observed after exposure to the same radiation delivered at a chronic dose rate of 0.08 cGy/min. The shape of the dose response was found to be quasi-linear for both dose rates, but, counter to providing support for a one-lesion mechanism, the yield of simple aberrations was greatly reduced by protracted exposure. Although chronic doses were delivered at rates low enough to produce damage exclusively by single-track action, this did not altogether eliminate the formation of complex aberrations, an analysis of which leads to the conclusion that a single track of low-LET radiation is capable of inducing complex exchanges requiring up to four proximate breaks for their formation. For acute exposures, the ratio of simple reciprocal translocations to simple dicentrics was near unity.

  5. Global properties of cellular automata

    International Nuclear Information System (INIS)

    Jen, E.

    1986-01-01

    Cellular automata are discrete mathematical systems that generate diverse, often complicated, behavior using simple deterministic rules. Analysis of the local structure of these rules makes possible a description of the global properties of the associated automata. A class of cellular automata that generate infinitely many aperoidic temporal sequences is defined,a s is the set of rules for which inverses exist. Necessary and sufficient conditions are derived characterizing the classes of ''nearest-neighbor'' rules for which arbitrary finite initial conditions (i) evolve to a homogeneous state; (ii) generate at least one constant temporal sequence

  6. Global Cooling: Effect of Urban Albedo on Global Temperature

    Energy Technology Data Exchange (ETDEWEB)

    Akbari, Hashem; Menon, Surabi; Rosenfeld, Arthur

    2007-05-22

    In many urban areas, pavements and roofs constitute over 60% of urban surfaces (roof 20-25%, pavements about 40%). The roof and the pavement albedo can be increased by about 0.25 and 0.10, respectively, resulting in a net albedo increase for urban areas of about 0.1. Many studies have demonstrated building cooling-energy savings in excess of 20% upon raising roof reflectivity from an existing 10-20% to about 60%. We estimate U.S. potential savings in excess of $1 billion (B) per year in net annual energy bills. Increasing albedo of urban surfaces can reduce the summertime urban temperature and improve the urban air quality. Increasing the urban albedo has the added benefit of reflecting more of the incoming global solar radiation and countering the effect of global warming. We estimate that increasing albedo of urban areas by 0.1 results in an increase of 3 x 10{sup -4} in Earth albedo. Using a simple global model, the change in air temperature in lowest 1.8 km of the atmosphere is estimated at 0.01K. Modelers predict a warming of about 3K in the next 60 years (0.05K/year). Change of 0.1 in urban albedo will result in 0.01K global cooling, a delay of {approx}0.2 years in global warming. This 0.2 years delay in global warming is equivalent to 10 Gt reduction in CO2 emissions.

  7. Changing global carbon cycle

    International Nuclear Information System (INIS)

    Canadell, Pep

    2007-01-01

    Full text: The increase in atmospheric carbon dioxide (C02) is the single largest human perturbation on the earth's radiative balance contributing to climate change. Its rate of change reflects the balance between anthropogenic carbon emissions and the dynamics of a number of terrestrial and ocean processes that remove or emit C02. It is the long term evolution of this balance that will determine to large extent the speed and magnitude of the human induced climate change and the mitigation requirements to stabilise atmospheric C02 concentrations at any given level. In this talk, we show new trends in global carbon sources and sinks, with particularly focus on major shifts occurring since 2000 when the growth rate of atmospheric C02 has reached its highest level on record. The acceleration in the C02 growth results from the combination of several changes in properties of the carbon cycle, including: acceleration of anthropogenic carbon emissions; increased carbon intensity of the global economy, and decreased efficiency of natural carbon sinks. We discuss in more detail some of the possible causes of the reduced efficiency of natural carbon sinks on land and oceans, such as the decreased net sink in the Southern Ocean and on terrestrial mid-latitudes due to world-wide occurrence of drought. All these changes reported here characterise a carbon cycle that is generating stronger than expected climate forcing, and sooner than expected

  8. From conceptual pluralism to practical agreement on policy: global responsibility for global health.

    Science.gov (United States)

    Ruger, Jennifer Prah; Hammonds, Rachel; Ooms, Gorik; Barry, Donna; Chapman, Audrey; Van Damme, Wim

    2015-10-28

    As the human cost of the global economic crisis becomes apparent the ongoing discussions surrounding the post-2015 global development framework continue at a frenzied pace. Given the scale and scope of increased globalization moving forward in a post-Millennium Development Goals era, to protect and realize health equity for all people, has never been more challenging or more important. The unprecedented nature of global interdependence underscores the importance of proposing policy solutions that advance realizing global responsibility for global health. This article argues for advancing global responsibility for global health through the creation of a Global Fund for Health. It suggests harnessing the power of the exceptional response to the combined epidemics of AIDS, TB and Malaria, embodied in the Global Fund to Fight AIDS, Tuberculosis and Malaria, to realize an expanded, reconceptualized Global Fund for Health. However this proposal creates both an analytical quandary embedded in conceptual pluralism and a practical dilemma for the scope and raison d'etre of a new Global Fund for Health. To address these issues we offer a logical framework for moving from conceptual pluralism in the theories supporting global responsibility for health to practical agreement on policy to realize this end. We examine how the innovations flowing from this exceptional response can be coupled with recent ideas and concepts, for example a global social protection floor, a Global Health Constitution or a Framework Convention for Global Health, that share the global responsibility logic that underpins a Global Fund for Health. The 2014 Lancet Commission on Global Governance for Health Report asks whether a single global health protection fund would be better for global health than the current patchwork of global and national social transfers. We concur with this suggestion and argue that there is much room for practical agreement on a Global Fund for Health that moves from the

  9. Surface core-level shifts for simple metals

    DEFF Research Database (Denmark)

    Aldén, Magnus; Skriver, Hans Lomholt; Johansson, Börje

    1994-01-01

    screening, whereby a SCLS becomes equivalent to the surface segregation energy of a core-ionized atom, a quantity we obtain by separate bulk and surface impurity calculations. The results are in good agreement with experiment in most of those cases where the data originates from single-crystal measurements....... We discuss the surface shifts of the electrostatic potentials and the band centers in order to trace the microscopic origin of the SCLS in the simple metals and find that the anomalous subsurface core-level shifts in beryllium are caused by charge dipoles, which persist several layers into the bulk...

  10. A simple technique for correction of relapsed overjet.

    Science.gov (United States)

    Kakkirala, Neelima; Saxena, Ruchi

    2014-01-01

    Class III malocclusions are usually growth related discrepancies, which often become more severe when growth is completed Orthognathic surgery can be a part of the treatment plan, although a good number of cases can be treated non-surgically by camouflage treatment. The purpose of this report is to review the relapse tendency in patients treated non-surgically. A simple technique is described to combat one such post-treatment relapse condition in an adult patient who had undergone orthodontic treatment by extraction of a single lower incisor.

  11. Simple method for correct enumeration of Staphylococcus aureus

    DEFF Research Database (Denmark)

    Haaber, J.; Cohn, M. T.; Petersen, A.

    2016-01-01

    culture. When grown in such liquid cultures, the human pathogen Staphylococcus aureus is characterized by its aggregation of single cells into clusters of variable size. Here, we show that aggregation during growth in the laboratory standard medium tryptic soy broth (TSB) is common among clinical...... and laboratory S. aureus isolates and that aggregation may introduce significant bias when applying standard enumeration methods on S. aureus growing in laboratory batch cultures. We provide a simple and efficient sonication procedure, which can be applied prior to optical density measurements to give...

  12. SIMCRI: a simple computer code for calculating nuclear criticality parameters

    International Nuclear Information System (INIS)

    Nakamaru, Shou-ichi; Sugawara, Nobuhiko; Naito, Yoshitaka; Katakura, Jun-ichi; Okuno, Hiroshi.

    1986-03-01

    This is a user's manual for a simple criticality calculation code SIMCRI. The code has been developed to facilitate criticality calculation on a single unit of nuclear fuel. SIMCRI makes an extensive survey with a little computing time. Cross section library MGCL for SIMCRI is the same one for the Monte Carlo criticality code KENOIV; it is, therefore, easy to compare the results of the two codes. SIMCRI solves eigenvalue problems and fixed source problems based on the one space point B 1 equation. The results include infinite and effective multiplication factor, critical buckling, migration area, diffusion coefficient and so on. SIMCRI is comprised in the criticality safety evaluation code system JACS. (author)

  13. Simple radiological indicators for staghorn calculi response to ESWL.

    Science.gov (United States)

    Murshidi, M S

    2006-01-01

    To evaluate staghorn calculi response to ESWL using simple radiological indicators which are stone size, stone homogeneity, and stone density. This is a prospective study of 60 patients with staghorn calculi where the majority had ESWL. The relationship between response and size, homogeneity and density is studied. Single staghorn calculus less than 4 cm, heterogeneous with stone density similar to bone or a little denser than bone has best response to ESWL. ESWL is useful as first line therapy for staghorn calculi less than 4 cm, heterogeneous with similar density to bone or a little denser than bone.

  14. New Results of Global Exponential Stabilization for BLDCMs System

    OpenAIRE

    Fengxia Tian; Fangchao Zhen; Guopeng Zhou; Xiaoxin Liao

    2015-01-01

    The global exponential stabilization for brushless direct current motor (BLDCM) system is studied. Four linear and simple feedback controllers are proposed to realize the global stabilization of BLDCM with exponential convergence rate; the control law used in each theorem is less conservative and more concise. Finally, an example is given to demonstrate the correctness of the proposed results.

  15. Fourier phase retrieval with a single mask by Douglas-Rachford algorithms.

    Science.gov (United States)

    Chen, Pengwen; Fannjiang, Albert

    2018-05-01

    The Fourier-domain Douglas-Rachford (FDR) algorithm is analyzed for phase retrieval with a single random mask. Since the uniqueness of phase retrieval solution requires more than a single oversampled coded diffraction pattern, the extra information is imposed in either of the following forms: 1) the sector condition on the object; 2) another oversampled diffraction pattern, coded or uncoded. For both settings, the uniqueness of projected fixed point is proved and for setting 2) the local, geometric convergence is derived with a rate given by a spectral gap condition. Numerical experiments demonstrate global, power-law convergence of FDR from arbitrary initialization for both settings as well as for 3 or more coded diffraction patterns without oversampling. In practice, the geometric convergence can be recovered from the power-law regime by a simple projection trick, resulting in highly accurate reconstruction from generic initialization.

  16. A simple model for binary star evolution

    International Nuclear Information System (INIS)

    Whyte, C.A.; Eggleton, P.P.

    1985-01-01

    A simple model for calculating the evolution of binary stars is presented. Detailed stellar evolution calculations of stars undergoing mass and energy transfer at various rates are reported and used to identify the dominant physical processes which determine the type of evolution. These detailed calculations are used to calibrate the simple model and a comparison of calculations using the detailed stellar evolution equations and the simple model is made. Results of the evolution of a few binary systems are reported and compared with previously published calculations using normal stellar evolution programs. (author)

  17. Globalization and inequality

    NARCIS (Netherlands)

    Mills, Melinda

    Globalization is increasingly linked to inequality, but with often divergent and polarized findings. Some researchers show that globalization accentuates inequality both within and between countries. Others maintain that these claims are patently incorrect, arguing that globalization has

  18. Exploring Late Globalization

    DEFF Research Database (Denmark)

    Turcan, Romeo V.

    2016-01-01

    literature on late globalization from sociocultural and economic perspectives. It illustrates in a vignette the character and features of late globalization observable in the withdrawal from foreign locations or deinternationalization of universities, as late globalizing entitis. The paper discusses...

  19. Globalization and economic cooperation

    Directory of Open Access Journals (Sweden)

    Javier Divar

    2006-12-01

    Full Text Available Economic globalization is nothing, really, that the universality of capitalism. Not globalized culture, and economic participation, and human rights, ... has only globalized market. We must react by substituting those materialistic values with cooperative economy.

  20. Simple and effective graphene laser processing for neuron patterning application

    Science.gov (United States)

    Lorenzoni, Matteo; Brandi, Fernando; Dante, Silvia; Giugni, Andrea; Torre, Bruno

    2013-06-01

    A straightforward fabrication technique to obtain patterned substrates promoting ordered neuron growth is presented. Chemical vapor deposition (CVD) single layer graphene (SLG) was machined by means of single pulse UV laser ablation technique at the lowest effective laser fluence in order to minimize laser damage effects. Patterned substrates were then coated with poly-D-lysine by means of a simple immersion in solution. Primary embryonic hippocampal neurons were cultured on our substrate, demonstrating an ordered interconnected neuron pattern mimicking the pattern design. Surprisingly, the functionalization is more effective on the SLG, resulting in notably higher alignment for neuron adhesion and growth. Therefore the proposed technique should be considered a valuable candidate to realize a new generation of highly specialized biosensors.

  1. Solar distillation between a simple and double-glazing

    Directory of Open Access Journals (Sweden)

    Abderrahmane KHECHEKHOUCHE

    2017-12-01

    Full Text Available The south-east region of Algeria suffers from a great socio-economic problem that affects a large population. Faced with the unavailability of drinking water, solar distillation; which appears to be a suitable and inexpensive solution; was adopted by local researchers. Improving the productivity of a solar greenhouse distiller is the subject of several researches in the world. As it is well known, distiller with simple glazing is wildly studied but unfortunately has feeble efficiency. Double glazing is a method that increases the efficiency of a flat solar collector. The idea is to use the same technique on a single-slope solar distiller (50 x 50 cm. Two glass plates separated by 1 cm between them air is trapped. Experience shows that this technique has a negative effect on the productivity of the distiller with a rate of 88.63%; it means 9 times. So double glazing is not recommended in the single slope solar distiller.

  2. A simple predictive model for the structure of the oceanic pycnocline

    Science.gov (United States)

    Gnanadesikan

    1999-03-26

    A simple theory for the large-scale oceanic circulation is developed, relating pycnocline depth, Northern Hemisphere sinking, and low-latitude upwelling to pycnocline diffusivity and Southern Ocean winds and eddies. The results show that Southern Ocean processes help maintain the global ocean structure and that pycnocline diffusion controls low-latitude upwelling.

  3. A simple approach to recycle broiler litter as animal feed | Makinde ...

    African Journals Online (AJOL)

    Broiler litter (BL) is a major waste from poultry production that constitutes serious disposal and environmental pollution problems globally despite its potential as animal feed. Therefore, the objective of this study was to develop a simple procedure for converting broiler litter into animal feed using wheat offal (WO) and cattle ...

  4. Rational non-Pu fuel-cycle composed simple power-stations and fissile producers

    International Nuclear Information System (INIS)

    Furukawa, K.; Mitachi, K.; Kato, Y.; Lecocq, A.

    1989-01-01

    In the next century, the fission breeder concept would not be practical for solving global energy problems. As a measure, a new rational is needed. In this paper the breeding fuel cycle system is proposed to establish the improvement in issues of safety, power-size flexibility, anti-terrorism and radio-waste, economy, etc. securing the simple operation, maintenance and chemical processing

  5. The Global File System

    Science.gov (United States)

    Soltis, Steven R.; Ruwart, Thomas M.; OKeefe, Matthew T.

    1996-01-01

    The global file system (GFS) is a prototype design for a distributed file system in which cluster nodes physically share storage devices connected via a network-like fiber channel. Networks and network-attached storage devices have advanced to a level of performance and extensibility so that the previous disadvantages of shared disk architectures are no longer valid. This shared storage architecture attempts to exploit the sophistication of storage device technologies whereas a server architecture diminishes a device's role to that of a simple component. GFS distributes the file system responsibilities across processing nodes, storage across the devices, and file system resources across the entire storage pool. GFS caches data on the storage devices instead of the main memories of the machines. Consistency is established by using a locking mechanism maintained by the storage devices to facilitate atomic read-modify-write operations. The locking mechanism is being prototyped in the Silicon Graphics IRIX operating system and is accessed using standard Unix commands and modules.

  6. Dynamics of unwinding of a simple entaglement

    NARCIS (Netherlands)

    Wiegel, F.W.; Michels, J.P.J.

    1987-01-01

    The dynamics of unwinding of a simple entanglement is studied in two ways, firstly using an optimal path approximation in the Rouse model and secondly by simulating the movement of a more realistic model using Brownian molecular dynamics

  7. A Simple Preparation Method for Diphosphoimidazole

    DEFF Research Database (Denmark)

    Rosenberg, T.

    1964-01-01

    A simple method for the preparation of diphosphoimidazole is presented that involves direct phosphorylation of imidazole by phosphorus oxychloride in alkaline aqueous solution. Details are given on the use of diphosphoimidazole in preparing sodium phosphoramidate and certain phosphorylated amino...

  8. simple and rapid spectrophotometric assay of levocetirizine

    African Journals Online (AJOL)

    Preferred Customer

    Simple, rapid, selective and fairly sensitive method is described for the ... Determination of small amounts of LCTZ in pharmaceutical preparations is important for .... sodium hydroxide and extraction of HCl-free-amine into chloroform followed ...

  9. Simple Perturbation Example for Quantum Chemistry.

    Science.gov (United States)

    Goodfriend, P. L.

    1985-01-01

    Presents a simple example that illustrates various aspects of the Rayleigh-Schrodinger perturbation theory. The example is a particularly good one because it is straightforward and can be compared with both the exact solution and with experimental data. (JN)

  10. The Invention Convention: Mind Meets Simple Machines.

    Science.gov (United States)

    Hadi-Tabassum, Samina

    1997-01-01

    Describes an Earth Day celebration where students had to design an invention made of simple machines that could crush an empty aluminum can through 10 rapid mechanical movements using materials foraged from the students' homes. (JRH)

  11. Simple and Clear Proofs of Stirling's Formula

    Science.gov (United States)

    Niizeki, Shozo; Araki, Makoto

    2010-01-01

    The purpose of our article is to show two simpler and clearer methods of proving Stirling's formula than the traditional and conventional ones. The distinction of our method is to use the simple trapezoidal formula.

  12. Low Cost, Simple, Intrauterine Insemination Procedure

    African Journals Online (AJOL)

    AJRH Managing Editor

    quite simple intrauterine insemination technique which may be performed in developing countries, without the need of sophisticated ... Cytoplasmic Sperm Injection (ICSI), are quite ... were administered only once by intramuscular injection ...

  13. Studies of global warming and global energy

    International Nuclear Information System (INIS)

    Inaba, Atsushi

    1993-01-01

    Global warming caused by increase in atmospheric CO 2 concentration has been the focus of many recent global energy studies. CO 2 is emitted to the atmosphere mainly from the combustion of fossil fuels. This means that global warming is fundamentally a problem of the global energy system. An analysis of the findings of recent global energy studies is made in this report. The results are categorized from the viewpoint of concern about global warming. The analysis includes energy use and CO 2 emissions, measures taken to restrain CO 2 emissions and the cost of such measure, and suggestions for long term global energy generation. Following this comparative analysis, each of the studies is reviewed in detail. (author) 63 refs

  14. Globalization and State Soverignty

    National Research Council Canada - National Science Library

    Islam, Mainul

    2003-01-01

    .... Globalized capital is reorganizing business firms and undermining national politics. Globalization creates vast new markets and gigantic new wealth, as well as widespread suffering, disorder and unrest...

  15. Substoichiometric method in the simple radiometric analysis

    International Nuclear Information System (INIS)

    Ikeda, N.; Noguchi, K.

    1979-01-01

    The substoichiometric method is applied to simple radiometric analysis. Two methods - the standard reagent method and the standard sample method - are proposed. The validity of the principle of the methods is verified experimentally in the determination of silver by the precipitation method, or of zinc by the ion-exchange or solvent-extraction method. The proposed methods are simple and rapid compared with the conventional superstoichiometric method. (author)

  16. Simple versus complex degenerative mitral valve disease.

    Science.gov (United States)

    Javadikasgari, Hoda; Mihaljevic, Tomislav; Suri, Rakesh M; Svensson, Lars G; Navia, Jose L; Wang, Robert Z; Tappuni, Bassman; Lowry, Ashley M; McCurry, Kenneth R; Blackstone, Eugene H; Desai, Milind Y; Mick, Stephanie L; Gillinov, A Marc

    2018-07-01

    At a center where surgeons favor mitral valve (MV) repair for all subsets of leaflet prolapse, we compared results of patients undergoing repair for simple versus complex degenerative MV disease. From January 1985 to January 2016, 6153 patients underwent primary isolated MV repair for degenerative disease, 3101 patients underwent primary isolated MV repair for simple disease (posterior prolapse), and 3052 patients underwent primary isolated MV repair for complex disease (anterior or bileaflet prolapse), based on preoperative echocardiographic images. Logistic regression analysis was used to generate propensity scores for risk-adjusted comparisons (n = 2065 matched pairs). Durability was assessed by longitudinal recurrence of mitral regurgitation and reoperation. Compared with patients with simple disease, those undergoing repair of complex pathology were more likely to be younger and female (both P values < .0001) but with similar symptoms (P = .3). The most common repair technique was ring/band annuloplasty (3055/99% simple vs 3000/98% complex; P = .5), followed by leaflet resection (2802/90% simple vs 2249/74% complex; P < .0001). Among propensity-matched patients, recurrence of severe mitral regurgitation 10 years after repair was 6.2% for simple pathology versus 11% for complex pathology (P = .007), reoperation at 18 years was 6.3% for simple pathology versus 11% for complex pathology, and 20-year survival was 62% for simple pathology versus 61% for complex pathology (P = .6). Early surgical intervention has become more common in patients with degenerative MV disease, regardless of valve prolapse complexity or symptom status. Valve repair was associated with similarly low operative risk and time-related survival but less durability in complex disease. Lifelong annual echocardiographic surveillance after MV repair is recommended, particularly in patients with complex disease. Copyright © 2018 The American Association for Thoracic Surgery

  17. Infinitivo simple y compuesto con predicados declarativos

    OpenAIRE

    Rodríguez Espiñeira, María José

    2012-01-01

    Este trabajo se centra en las diferencias semánticas y sintácticas que presentan las construcciones de infinitivo simple y compuesto que actúan como objeto directo de predicados declarativos. El tema despierta interés por varios motivos: (1) Se trata de un subconjunto de verbos que subordinan infinitivos simples de un elenco restringido, pero que admiten regularmente infinitivos compuestos.

  18. Simple Lie algebras and Dynkin diagrams

    International Nuclear Information System (INIS)

    Buccella, F.

    1983-01-01

    The following theorem is studied: in a simple Lie algebra of rank p there are p positive roots such that all the other n-3p/2 positive roots are linear combinations of them with integer non negative coefficients. Dykin diagrams are built by representing the simple roots with circles and drawing a junction between the roots. Five exceptional algebras are studied, focusing on triple junction algebra, angular momentum algebra, weights of the representation, antisymmetric tensors, and subalgebras

  19. Signed Young Modules and Simple Specht Modules

    OpenAIRE

    Danz, Susanne; Lim, Kay Jin

    2015-01-01

    By a result of Hemmer, every simple Specht module of a finite symmetric group over a field of odd characteristic is a signed Young module. While Specht modules are parametrized by partitions, indecomposable signed Young modules are parametrized by certain pairs of partitions. The main result of this article establishes the signed Young module labels of simple Specht modules. Along the way we prove a number of results concerning indecomposable signed Young modules that are of independent inter...

  20. Global structure of a polynomial autonomous system on the plane

    International Nuclear Information System (INIS)

    Nguyen Van Chau.

    1991-10-01

    This note is to study the global behaviour of a polynomial autonomous system on the plane with divergence non-positive outside a bounded set. It is shown that in some certain conditions the global structure of such system can be simple. The main result here can be seen as an improvement of the result of Olech and Meister concerning with the global asymptotical stable conjecture of Markur and Yamable and the Jacobian Conjecture. (author). 13 refs

  1. A simple, one-tube assay for the simultaneous detection and diagnosis of ten Australian poultry Eimeria.

    Science.gov (United States)

    Godwin, Rosamond M; Morgan, Jess A T

    2014-02-01

    Coccidiosis is a costly worldwide enteric disease of chickens caused by parasites of the genus Eimeria. At present, there are seven described species that occur globally and a further three undescribed, operational taxonomic units (OTUs X, Y, and Z) that are known to infect chickens from Australia. Species of Eimeria have both overlapping morphology and pathology and frequently occur as mixed-species infections. This makes definitive diagnosis with currently available tests difficult and, to date, there is no test for the detection of the three OTUs. This paper describes the development of a PCR-based assay that is capable of detecting all ten species of Eimeria, including OTUs X, Y, and Z in field samples. The assay is based on a single set of generic primers that amplifies a single diagnostic fragment from the mitochondrial genome of each species. This one-tube assay is simple, low-cost, and has the capacity to be high throughput. It will therefore be of great benefit to the poultry industry for Eimeria detection and control, and the confirmation of identity and purity of vaccine strains. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Simple classical model for Fano statistics in radiation detectors

    Energy Technology Data Exchange (ETDEWEB)

    Jordan, David V. [Pacific Northwest National Laboratory, National Security Division - Radiological and Chemical Sciences Group PO Box 999, Richland, WA 99352 (United States)], E-mail: David.Jordan@pnl.gov; Renholds, Andrea S.; Jaffe, John E.; Anderson, Kevin K.; Rene Corrales, L.; Peurrung, Anthony J. [Pacific Northwest National Laboratory, National Security Division - Radiological and Chemical Sciences Group PO Box 999, Richland, WA 99352 (United States)

    2008-02-01

    A simple classical model that captures the essential statistics of energy partitioning processes involved in the creation of information carriers (ICs) in radiation detectors is presented. The model pictures IC formation from a fixed amount of deposited energy in terms of the statistically analogous process of successively sampling water from a large, finite-volume container ('bathtub') with a small dipping implement ('shot or whiskey glass'). The model exhibits sub-Poisson variance in the distribution of the number of ICs generated (the 'Fano effect'). Elementary statistical analysis of the model clarifies the role of energy conservation in producing the Fano effect and yields Fano's prescription for computing the relative variance of the IC number distribution in terms of the mean and variance of the underlying, single-IC energy distribution. The partitioning model is applied to the development of the impact ionization cascade in semiconductor radiation detectors. It is shown that, in tandem with simple assumptions regarding the distribution of energies required to create an (electron, hole) pair, the model yields an energy-independent Fano factor of 0.083, in accord with the lower end of the range of literature values reported for silicon and high-purity germanium. The utility of this simple picture as a diagnostic tool for guiding or constraining more detailed, 'microscopic' physical models of detector material response to ionizing radiation is discussed.

  3. Ability of Aphis gossypii and Myzus persicae to Transmit Cucumber mosaic virus in Single and Mixed Infection with Two Potyviruses to Zucchini Squash Eficiência dos afídeos Aphis gossypii e Myzus persicae na transmissão do Cucumber mosaic virus em infecção simples e mista com dois Potyvirus para abobrinha de moita

    Directory of Open Access Journals (Sweden)

    Zayame Vegette Pinto

    2008-06-01

    Full Text Available The main objective of this work was to investigate the ability of Aphis gossypii and Myzus persicae to transmit Cucumber mosaic virus (CMV singly and mixed with two potyviruses (Papaya ringspot virus - type W, PRSV-W and Zucchini yellow mosaic virus, ZYMV, to zucchini squash plants (Cucurbita pepo. The results showed that the potyviruses in general were more efficiently transmitted by both species of aphids as compared to CMV. The transmission of PRSV-W, ZYMV and CMV separately was more efficient than in mixture.O objetivo desse trabalho foi estudar a eficiência de Aphis gossypii e Myzus persicae na transmissão do vírus do mosaico do pepino (Cucumber mosaic virus, CMV, isoladamente e em mistura com duas espécies de potyvirus (Vírus do mosaico do mamoeiro = Papaya ringspot virus - type W, PRSV-W e Vírus do mosaico amarelo da abobrinha = Zucchini yellow mosaic virus, ZYMV, para planta-testes de abobrinha de moita (Cucurbita pepo. Os dois potyvirus em geral foram transmitidos com mais eficiência pelas duas espécies de afídeos do que o CMV. A transmissão do PRSV-W, ZYMV e CMV, separadamente, foi mais eficiente do que em mistura.

  4. Development of a simple and sensitive liquid chromatography triple quadrupole mass spectrometry (LC-MS/MS) method for the determination of cannabidiol (CBD), Δ9-tetrahydrocannabinol (THC) and its metabolites in rat whole blood after oral administration of a single high dose of CBD.

    Science.gov (United States)

    Palazzoli, Federica; Citti, Cinzia; Licata, Manuela; Vilella, Antonietta; Manca, Letizia; Zoli, Michele; Vandelli, Maria Angela; Forni, Flavio; Cannazza, Giuseppe

    2018-02-20

    The investigation of the possible conversion of cannabidiol (CBD) into Δ 9 -tetrahydrocannabinol (THC) in vivo after oral administration of CBD is reported herein since recent publications suggested a rapid conversion in simulated gastric fluid. To this end, single high dose of CBD (50mg/kg) was administered orally to rats and their blood was collected after 3 and 6h. A highly sensitive and selective LC-MS/MS method was developed and fully validated in compliance with the Scientific Working Group of Forensic Toxicology (SWGTOX) standard practices for method validation in forensic toxicology. This method also involved the optimization of cannabinoids and their metabolites extraction in order to remove co-eluting phospholipids and increase the sensitivity of the MS detection. Neither THC nor its metabolites were detected in rat whole blood after 3 or 6h from CBD administration. After oral administration, the amount of CBD dissolved in olive oil was higher than that absorbed from an ethanolic solution. This could be explained by the protection of lipid excipients towards CBD from acidic gastric juice. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Chained learning architectures in a simple closed-loop behavioural context

    DEFF Research Database (Denmark)

    Kulvicius, Tomas; Porr, Bernd; Wörgötter, Florentin

    2007-01-01

    are very simple and consist of single learning unit. The current study is trying to solve this problem focusing on chained learning architectures in a simple closed-loop behavioural context. METHODS: We applied temporal sequence learning (Porr B and Wörgötter F 2006) in a closed-loop behavioural system...... where a driving robot learns to follow a line. Here for the first time we introduced two types of chained learning architectures named linear chain and honeycomb chain. We analyzed such architectures in an open and closed-loop context and compared them to the simple learning unit. CONCLUSIONS...

  6. Tempo de reação simples auditivo e visual em surfistas com diferentes níveis de habilidade: comparação entre atletas profissionais, amadores e praticantes Auditory and visual single reaction span in surfers with different ability levels: comparison of professional, amateur athletes and surf practitioners

    Directory of Open Access Journals (Sweden)

    César Augusto Otero Vaghetti

    2007-04-01

    Full Text Available O tempo de reação simples (TRS representa o nível de coordenação neuromuscular, no qual os estímulos visuais, auditivos ou táteis são decodificados pelo corpo através de diferentes processos físico-químicos e mecânicos. O objetivo desta pesquisa foi identificar os TRS auditivo e visual em surfistas profissionais, amadores e praticantes, verificar se existem diferenças estatísticas entre os grupos de surfistas e correlacionar os tempos de reação com a performance dos atletas. Participaram deste estudo 103 surfistas: 42 atletas profissionais do sexo masculino (brasileiros e estrangeiros, 11 atletas profissionais do sexo feminino, 25 atletas amadores universitários e 25 praticantes de surfe. A coleta de dados foi realizada nas praias onde aconteceram os respectivos eventos, WQS (World Qualifyng Series, etapa do circuito mundial, Superfsurf (etapa do campeonato brasileiro de surfe profissional, CCSU (etapa do circuito catarinense de surfe universitário. Foram utilizados como instrumentação um interruptor com uma tecla de sensibilidade de 0,8N, um LED para estímulo visual, duas caixas acústicas, com 315Hz de freqüência e 81dB de pressão sonora, para estímulo auditivo e um dispositivo eletrônico com a finalidade de gerar o sinal auditivo, visual e de sincronismo. A aquisição dos dados foi realizada utilizando o software SAD versão 32. Foram encontradas diferenças estatisticamente significativas para os TRS auditivo e visual entre os profissionais (masculinos versus praticantes, profissionais (femininos versus praticantes. Entre os amadores versus praticantes foram encontradas diferenças estatisticamente significativas apenas para o TRS visual, com TRS menores para os mais experientes. Uma correlação positiva foi encontrada para o TRS visual entre os profissionais (femininos versus no ranking.The reaction span RS (RTS represents the level of neuromuscular coordination in which the visual, auditory or touch stimuli are

  7. Simple additive simulation overestimates real influence: altered nitrogen and rainfall modulate the effect of warming on soil carbon fluxes.

    Science.gov (United States)

    Ni, Xiangyin; Yang, Wanqin; Qi, Zemin; Liao, Shu; Xu, Zhenfeng; Tan, Bo; Wang, Bin; Wu, Qinggui; Fu, Changkun; You, Chengming; Wu, Fuzhong

    2017-08-01

    Experiments and models have led to a consensus that there is positive feedback between carbon (C) fluxes and climate warming. However, the effect of warming may be altered by regional and global changes in nitrogen (N) and rainfall levels, but the current understanding is limited. Through synthesizing global data on soil C pool, input and loss from experiments simulating N deposition, drought and increased precipitation, we quantified the responses of soil C fluxes and equilibrium to the three single factors and their interactions with warming. We found that warming slightly increased the soil C input and loss by 5% and 9%, respectively, but had no significant effect on the soil C pool. Nitrogen deposition alone increased the soil C input (+20%), but the interaction of warming and N deposition greatly increased the soil C input by 49%. Drought alone decreased the soil C input by 17%, while the interaction of warming and drought decreased the soil C input to a greater extent (-22%). Increased precipitation stimulated the soil C input by 15%, but the interaction of warming and increased precipitation had no significant effect on the soil C input. However, the soil C loss was not significantly affected by any of the interactions, although it was constrained by drought (-18%). These results implied that the positive C fluxes-climate warming feedback was modulated by the changing N and rainfall regimes. Further, we found that the additive effects of [warming × N deposition] and [warming × drought] on the soil C input and of [warming × increased precipitation] on the soil C loss were greater than their interactions, suggesting that simple additive simulation using single-factor manipulations may overestimate the effects on soil C fluxes in the real world. Therefore, we propose that more multifactorial experiments should be considered in studying Earth systems. © 2016 John Wiley & Sons Ltd.

  8. Contribution to the asymptotic estimation of the global error of single step numerical integration methods. Application to the simulation of electric power networks; Contribution a l'estimation asymptotique de l'erreur globale des methodes d'integration numerique a un pas. Application a la simulation des reseaux electriques

    Energy Technology Data Exchange (ETDEWEB)

    Aid, R.

    1998-01-07

    This work comes from an industrial problem of validating numerical solutions of ordinary differential equations modeling power systems. This problem is solved using asymptotic estimators of the global error. Four techniques are studied: Richardson estimator (RS), Zadunaisky's techniques (ZD), integration of the variational equation (EV), and Solving for the correction (SC). We give some precisions on the relative order of SC w.r.t. the order of the numerical method. A new variant of ZD is proposed that uses the Modified Equation. In the case of variable step-size, it is shown that under suitable restriction, on the hypothesis of the step-size selection, ZD and SC are still valid. Moreover, some Runge-Kutta methods are shown to need less hypothesis on the step-sizes to exhibit a valid order of convergence for ZD and SC. Numerical tests conclude this analysis. Industrial cases are given. Finally, an algorithm to avoid the a priori specification of the integration path for complex time differential equations is proposed. (author)

  9. Is globalization healthy: a statistical indicator analysis of the impacts of globalization on health.

    Science.gov (United States)

    Martens, Pim; Akin, Su-Mia; Maud, Huynen; Mohsin, Raza

    2010-09-17

    It is clear that globalization is something more than a purely economic phenomenon manifesting itself on a global scale. Among the visible manifestations of globalization are the greater international movement of goods and services, financial capital, information and people. In addition, there are technological developments, more transboundary cultural exchanges, facilitated by the freer trade of more differentiated products as well as by tourism and immigration, changes in the political landscape and ecological consequences. In this paper, we link the Maastricht Globalization Index with health indicators to analyse if more globalized countries are doing better in terms of infant mortality rate, under-five mortality rate, and adult mortality rate. The results indicate a positive association between a high level of globalization and low mortality rates. In view of the arguments that globalization provides winners and losers, and might be seen as a disequalizing process, we should perhaps be careful in interpreting the observed positive association as simple evidence that globalization is mostly good for our health. It is our hope that a further analysis of health impacts of globalization may help in adjusting and optimising the process of globalization on every level in the direction of a sustainable and healthy development for all.

  10. Is globalization healthy: a statistical indicator analysis of the impacts of globalization on health

    Directory of Open Access Journals (Sweden)

    Martens Pim

    2010-09-01

    Full Text Available Abstract It is clear that globalization is something more than a purely economic phenomenon manifesting itself on a global scale. Among the visible manifestations of globalization are the greater international movement of goods and services, financial capital, information and people. In addition, there are technological developments, more transboundary cultural exchanges, facilitated by the freer trade of more differentiated products as well as by tourism and immigration, changes in the political landscape and ecological consequences. In this paper, we link the Maastricht Globalization Index with health indicators to analyse if more globalized countries are doing better in terms of infant mortality rate, under-five mortality rate, and adult mortality rate. The results indicate a positive association between a high level of globalization and low mortality rates. In view of the arguments that globalization provides winners and losers, and might be seen as a disequalizing process, we should perhaps be careful in interpreting the observed positive association as simple evidence that globalization is mostly good for our health. It is our hope that a further analysis of health impacts of globalization may help in adjusting and optimising the process of globalization on every level in the direction of a sustainable and healthy development for all.

  11. Globalization challenges in a globalized world

    Directory of Open Access Journals (Sweden)

    Dr.Sc. Gjon Boriçi

    2016-01-01

    Full Text Available Globalization is an ongoing phenomenon trying to redefine the economic, social, cultural and political dynamics of contemporary societies. The communication among countries and not only them, has been increased expanding political ties, making possible greater economic integration and wider cultural relations combined with augmented global wealth across the world. But, the process of globalization is in wider terms considered a beneficial one, but also viewed by some countries as a menace to national sovereignty and national culture. This paper tries to explain the obstacles to the process of globalization and its attendant benefits. Although globalization has arisen as a result of a more stable world, the factors that had contributed to its rise also help the factions interested to bring destabilization. In an academic approach in this article, between the research and comparative methods, I have been trying to get the maxims between economy, politics and diplomacy in their efforts of affecting the global era.

  12. Cosmic global strings

    International Nuclear Information System (INIS)

    Sikivie, P.

    1991-01-01

    The topics are: global strings; the gravitational field of a straight global string; how do global strings behave?; the axion cosmological energy density; computer simulations of the motion and decay of global strings; electromagnetic radiation from the conversion of Nambu-Goldstone bosons in astrophysical magnetic fields. (orig.)

  13. Globalization and business ethics

    OpenAIRE

    Khadartseva, L.; Agnaeva, L.

    2014-01-01

    It is assumed that local conditions of markets may be different, but some global markets, ethics and social responsibility principles should be applicable to all markets. As markets globalize and an increasing proportion of business activity transcends national borders, institutions need to help manage, regulate, and police the global marketplace, and to promote the establishment of multinational treaties to govern the global business system

  14. Genetics of simple and complex host-parasite interactions

    International Nuclear Information System (INIS)

    Sidhu, G.S.; Webster, J.M.

    1977-01-01

    In nature a host plant can be viewed as a miniature replica of an ecological system where true and incidental parasites share the same habitat. Consequently, they influence each other's presence directly by interspecific interaction, and indirectly by inducing changes in the host's physiology and so form disease complexes. Since all physiological phenomena have their counterpart in the respective genetic systems of interacting organisms, valuable genetic information can be derived from the analysis of complex parasitic systems. Disease complexes may be classified according to the nature of interaction between various parasites on the same host. One parasite may nullify the host's resistance to another (e.g. Tomato - Meloidogyne incognita + Fusarium oxysporum lycopersici system). Conversely, a parasite may invoke resistance in the host against another parasite (e.g. Tomato - Fusarium oxysporum lycopersici + Verticillium albo atrum system). From the study of simple parasitic systems we know that resistance versus susceptibility against a single parasite is normally monogenically controlled. However, when more than one parasite interacts to invoke or nullify each other's responses on the same host plant, the genetic results suggest epistatic ratios. Nevertheless, epistatic ratios have been obtained also from simple parasitic systems owing to gene interaction. The epistatic ratios obtained from complex and simple parasitic systems are contrasted and compared. It is suggested that epistatic ratios obtained from simple parasitic systems may, in fact, be artifacts resulting from complex parasitic associations that often occur in nature. Polygenic inheritance and the longevity of a cultivar is also discussed briefly in relation to complex parasitic associations. Induced mutations can play a significant role in the study of complex parasitic associations, and thus can be very useful in controlling plant diseases

  15. Proton facility economics: the importance of "simple" treatments.

    Science.gov (United States)

    Johnstone, Peter A S; Kerstiens, John; Richard, Helsper

    2012-08-01

    Given the cost and debt incurred to build a modern proton facility, impetus exists to minimize treatment of patients with complex setups because of their slower throughput. The aim of this study was to determine how many "simple" cases are necessary given different patient loads simply to recoup construction costs and debt service, without beginning to cover salaries, utilities, beam costs, and so on. Simple cases are ones that can be performed quickly because of an easy setup for the patient or because the patient is to receive treatment to just one or two fields. A "standard" construction cost and debt for 1, 3, and 4 gantry facilities were calculated from public documents of facilities built in the United States, with 100% of the construction funded through standard 15-year financing at 5% interest. Clinical best case (that each room was completely scheduled with patients over a 14-hour workday) was assumed, and a statistical analysis was modeled with debt, case mix, and payer mix moving independently. Treatment times and reimbursement data from the investigators' facility for varying complexities of patients were extrapolated for varying numbers treated daily. Revenue assumptions of $X per treatment were assumed both for pediatric cases (a mix of Medicaid and private payer) and state Medicare simple case rates. Private payer reimbursement averages $1.75X per treatment. The number of simple patients required daily to cover construction and debt service costs was then derived. A single gantry treating only complex or pediatric patients would need to apply 85% of its treatment slots simply to service debt. However, that same room could cover its debt treating 4 hours of simple patients, thus opening more slots for complex and pediatric patients. A 3-gantry facility treating only complex and pediatric cases would not have enough treatment slots to recoup construction and debt service costs at all. For a 4-gantry center, focusing on complex and pediatric cases alone

  16. Advances in stochastic and deterministic global optimization

    CERN Document Server

    Zhigljavsky, Anatoly; Žilinskas, Julius

    2016-01-01

    Current research results in stochastic and deterministic global optimization including single and multiple objectives are explored and presented in this book by leading specialists from various fields. Contributions include applications to multidimensional data visualization, regression, survey calibration, inventory management, timetabling, chemical engineering, energy systems, and competitive facility location. Graduate students, researchers, and scientists in computer science, numerical analysis, optimization, and applied mathematics will be fascinated by the theoretical, computational, and application-oriented aspects of stochastic and deterministic global optimization explored in this book. This volume is dedicated to the 70th birthday of Antanas Žilinskas who is a leading world expert in global optimization. Professor Žilinskas's research has concentrated on studying models for the objective function, the development and implementation of efficient algorithms for global optimization with single and mu...

  17. The Governance of Global Wealth Chains

    DEFF Research Database (Denmark)

    Seabrooke, Leonard; Wigan, Duncan

    ) innovation capacities among suppliers of products used in wealth chains. We then differentiate five types of global value chain governance - market, modular, relational, captive, and hierarchy - which range from simple ‘off shelf’ products shielded from regulators by advantageous international tax laws...... to highly complex and flexible innovative financial products produced by large financial institutions and corporations. This paper highlights how Global Wealth Chains intersect with value chains and real economies, and provides three brief case studies on offshore shell companies, family property trusts......This working paper creates a theoretical framework to explain how Global Wealth Chains are created, maintained, and governed. We draw upon different strands of literature, including scholarship in international political economy and economic geography on Global Value Chains, literature on finance...

  18. The Governance of Global Wealth Chains

    DEFF Research Database (Denmark)

    Seabrooke, Leonard; Wigan, Duncan

    liability and (3) innovation capacities among suppliers of products used in wealth chains. We then differentiate five types of global value chain governance - market, modular, relational, captive, an d hierarchy – which range from simple ‘off shelf’ products shielded from regulators by advantageous...... international tax laws to highly complex and flexible innovative financial products produced by large financial institutions and corporations. This article highlights how Global Wealth Cha ins intersect with value chains and real economies, and provides three brief case studies on offshore shell companies......This introduction to the Special Issue creates a theoretical framework to explain how Global Wealth Chains are created, maintained, and governed. We draw upon different strands of literature, including scholarship in international political economy and economic geography on Global Value Chains...

  19. The Governance of Global Wealth Chains

    DEFF Research Database (Denmark)

    Seabrooke, Leonard; Wigan, Duncan

    2017-01-01

    This article offers a theoretical framework to explain how Global Wealth Chains (GWCs) are created, maintained, and governed. We draw upon different strands of literature, including scholarship in International Political Economy and Economic Geography on Global Value Chains, literature on finance...... innovative financial products produced by large financial institutions and corporations. This article highlights how GWCs intersect with value chains, and provides brief case examples of wealth chains and how they interact.......This article offers a theoretical framework to explain how Global Wealth Chains (GWCs) are created, maintained, and governed. We draw upon different strands of literature, including scholarship in International Political Economy and Economic Geography on Global Value Chains, literature on finance...... capacities among suppliers of products used in wealth chains. We then differentiate five types of GWC governance – Market, Modular, Relational, Captive, and Hierarchy – which range from simple ‘off shelf’ products shielded from regulators by advantageous international tax laws to highly complex and flexible...

  20. The Design of SimpleITK

    Directory of Open Access Journals (Sweden)

    Bradley Christopher Lowekamp

    2013-12-01

    Full Text Available SimpleITK is a new interface to the Insight Segmentation andRegistration Toolkit (ITK designed to facilitate rapid prototyping, educationand scientific activities, via high level programminglanguages. ITK is a templated C++ library of image processingalgorithms and frameworks for biomedical and other applications, andit was designed to be generic, flexible and extensible. Initially, ITKprovided a direct wrapping interface to languages such as Python andTcl through the WrapITK system. Unlike WrapITK, which exposed ITK'scomplex templated interface, SimpleITK was designed to provide an easyto use and simplified interface to ITK's algorithms. It includesprocedural methods, hides ITK's demand driven pipeline, and provides atemplate-less layer. Also SimpleITK provides practical conveniencessuch as binary distribution packages and overloaded operators. Ouruser-friendly design goals dictated a departure from the directinterface wrapping approach of WrapITK, towards a new facadeclass structure that only exposes the required functionality, hidingITK's extensive template use. Internally SimpleITK utilizes a manualdescription of each filter with code-generation and advanced C++meta-programming to provide the higher-level interface, bringing thecapabilities of ITK to a wider audience. SimpleITK is licensed asopen source software under the Apache License Version 2.0 and more informationabout downloading it can be found at http://www.simpleitk.org.

  1. GLOBAL RELATIONSHIP MANAGEMENT

    OpenAIRE

    Er Kirtesh Jailia; Mrs.Manisha jailia; Er.Priyanka Jailia

    2010-01-01

    In this paper we are going to discuss about the concept of Global relationship management. This is an important concept because now a day the whole business community is moving globally, means the geographical boundaries are of no more concern for the business communities. The global thinking of the business communities leads to the global relationship hence it is important for them to effectively manage such global relationship so that they can achieve what they want. The main concern is ove...

  2. A Global Stock and Bond Model

    OpenAIRE

    Connor, Gregory

    1996-01-01

    Factor models are now widely used to support asset selection decisions. Global asset allocation, the allocation between stocks versus bonds and among nations, usually relies instead on correlation analysis of international equity and bond indexes. It would be preferable to have a single integrated framework for both asset selection and asset allocation. This framework would require a factor model applicable at an asset or country level, as well as at a global level,...

  3. Vortex breakdown in simple pipe bends

    Science.gov (United States)

    Ault, Jesse; Shin, Sangwoo; Stone, Howard

    2016-11-01

    Pipe bends and elbows are one of the most common fluid mechanics elements that exists. However, despite their ubiquity and the extensive amount of research related to these common, simple geometries, unexpected complexities still remain. We show that for a range of geometries and flow conditions, these simple flows experience unexpected fluid dynamical bifurcations resembling the bubble-type vortex breakdown phenomenon. Specifically, we show with simulations and experiments that recirculation zones develop within the bends under certain conditions. As a consequence, fluid and particles can remain trapped within these structures for unexpectedly-long time scales. We also present simple techniques to mitigate this recirculation effect which can potentially have impact across industries ranging from biomedical and chemical processing to food and health sciences.

  4. Analyzing Global Components in Developmental Dyscalculia and Dyslexia.

    Science.gov (United States)

    Filippo, Gloria Di; Zoccolotti, Pierluigi

    2018-01-01

    The study examined whether developmental deficits in reading and numerical skills could be expressed in terms of global factors by reference to the rate and amount (RAM) and difference engine (DEM) models. From a sample of 325 fifth grade children, we identified 5 children with dyslexia, 16 with dyscalculia, 7 with a "mixed pattern," and 49 control children. Children were asked to read aloud words presented individually that varied for frequency and length and to respond (either vocally or manually) to a series of simple number tasks (addition, subtraction, number reading, and number comparisons). Reaction times were measured. Results indicated that the deficit of children with dyscalculia and children with a mixed pattern on numerical tasks could be explained by a single global factor, similarly to the reading deficit shown by children with dyslexia. As predicted by the DEM, increases in task difficulty were accompanied by a corresponding increase in inter-individual variability for both the reading and numerical tasks. These relationships were constant across the four groups of children but differed in terms of slope and intercept on the x -axis, indicating that two different general rules underlie performance in reading and numerical skills. The study shows for the first time that, as previously shown for reading, also numerical performance can be explained with reference to a global factor. The advantage of this approach is that it takes into account the over-additivity effect, i.e., the presence of larger group differences in the case of more difficult conditions over and above the characteristics of the experimental conditions. It is concluded that reference to models such as the RAM and DEM can be useful in delineating the characteristics of the dyscalculic deficit as well as in the description of co-morbid disturbances, as in the case of dyslexia and dyscalculia.

  5. Analyzing Global Components in Developmental Dyscalculia and Dyslexia

    Directory of Open Access Journals (Sweden)

    Gloria Di Filippo

    2018-02-01

    Full Text Available The study examined whether developmental deficits in reading and numerical skills could be expressed in terms of global factors by reference to the rate and amount (RAM and difference engine (DEM models. From a sample of 325 fifth grade children, we identified 5 children with dyslexia, 16 with dyscalculia, 7 with a “mixed pattern,” and 49 control children. Children were asked to read aloud words presented individually that varied for frequency and length and to respond (either vocally or manually to a series of simple number tasks (addition, subtraction, number reading, and number comparisons. Reaction times were measured. Results indicated that the deficit of children with dyscalculia and children with a mixed pattern on numerical tasks could be explained by a single global factor, similarly to the reading deficit shown by children with dyslexia. As predicted by the DEM, increases in task difficulty were accompanied by a corresponding increase in inter-individual variability for both the reading and numerical tasks. These relationships were constant across the four groups of children but differed in terms of slope and intercept on the x-axis, indicating that two different general rules underlie performance in reading and numerical skills. The study shows for the first time that, as previously shown for reading, also numerical performance can be explained with reference to a global factor. The advantage of this approach is that it takes into account the over-additivity effect, i.e., the presence of larger group differences in the case of more difficult conditions over and above the characteristics of the experimental conditions. It is concluded that reference to models such as the RAM and DEM can be useful in delineating the characteristics of the dyscalculic deficit as well as in the description of co-morbid disturbances, as in the case of dyslexia and dyscalculia.

  6. TRSkit: A Simple Digital Library Toolkit

    Science.gov (United States)

    Nelson, Michael L.; Esler, Sandra L.

    1997-01-01

    This paper introduces TRSkit, a simple and effective toolkit for building digital libraries on the World Wide Web. The toolkit was developed for the creation of the Langley Technical Report Server and the NASA Technical Report Server, but is applicable to most simple distribution paradigms. TRSkit contains a handful of freely available software components designed to be run under the UNIX operating system and served via the World Wide Web. The intended customer is the person that must continuously and synchronously distribute anywhere from 100 - 100,000's of information units and does not have extensive resources to devote to the problem.

  7. Assessment of daylight quality in simple rooms

    DEFF Research Database (Denmark)

    Johnsen, Kjeld; Dubois, Marie-Claude; Sørensen, Karl Grau

    The present report documents the results of a study on daylight conditions in simple rooms of residential buildings. The overall objective of the study was to develop a basis for a method for the assessment of daylight quality in a room with simple geometry and window configurations. As a tool...... in daylighting conditions for a number of lighting parameters. The results gave clear indications of, for instance, which room would be the brightest, under which conditions might glare be a problem and which type of window would yield the greatest luminous variation (or visual interest), etc....

  8. Strong Bisimilarity of Simple Process Algebras

    DEFF Research Database (Denmark)

    Srba, Jirí

    2003-01-01

    We study bisimilarity and regularity problems of simple process algebras. In particular, we show PSPACE-hardness of the following problems: (i) strong bisimilarity of Basic Parallel Processes (BPP), (ii) strong bisimilarity of Basic Process Algebra (BPA), (iii) strong regularity of BPP, and (iv......) strong regularity of BPA. We also demonstrate NL-hardness of strong regularity problems for the normed subclasses of BPP and BPA. Bisimilarity problems of simple process algebras are introduced in a general framework of process rewrite systems, and a uniform description of the new techniques used...

  9. Simple gas chromatographic method for furfural analysis.

    Science.gov (United States)

    Gaspar, Elvira M S M; Lopes, João F

    2009-04-03

    A new, simple, gas chromatographic method was developed for the direct analysis of 5-hydroxymethylfurfural (5-HMF), 2-furfural (2-F) and 5-methylfurfural (5-MF) in liquid and water soluble foods, using direct immersion SPME coupled to GC-FID and/or GC-TOF-MS. The fiber (DVB/CAR/PDMS) conditions were optimized: pH effect, temperature, adsorption and desorption times. The method is simple and accurate (RSDfurfurals will contribute to characterise and quantify their presence in the human diet.

  10. A simple technique for laparoscopic gastrostomy.

    Science.gov (United States)

    Murphy, C; Rosemurgy, A S; Albrink, M H; Carey, L C

    1992-05-01

    While endoscopically placed gastrostomy tubes are routinely simple, they are not always feasible. Endoscopic technique also does not uniformly secure the tube to the abdominal wall, which presents possible complications, including leakage, accidental early tube removal, intraperitoneal catheter migration and necrosis of the stomach or abdominal wall because of excessive traction. Presented herein is a technique that is rapid, simple and eliminates some of these potential complications. The technique is easily combined with other operative procedures, such as tracheostomy, is done under direct vision, can be performed quickly with intravenous sedation and local anesthetic and is a safe method of tube placement for enteral feeding or gastric decompression.

  11. Simple 2-representations and Classification of Categorifications

    DEFF Research Database (Denmark)

    Agerholm, Troels

    We consider selfadjoint functors defined on categories of modules over finite dimensional algebras and classify those that satisfy some simple relations. In particular we classify self- adjoint idempotents and selfadjoint squareroots of a multiple of the identity functor. This is related to the t......We consider selfadjoint functors defined on categories of modules over finite dimensional algebras and classify those that satisfy some simple relations. In particular we classify self- adjoint idempotents and selfadjoint squareroots of a multiple of the identity functor. This is related...

  12. Molecular implementation of simple logic programs.

    Science.gov (United States)

    Ran, Tom; Kaplan, Shai; Shapiro, Ehud

    2009-10-01

    Autonomous programmable computing devices made of biomolecules could interact with a biological environment and be used in future biological and medical applications. Biomolecular implementations of finite automata and logic gates have already been developed. Here, we report an autonomous programmable molecular system based on the manipulation of DNA strands that is capable of performing simple logical deductions. Using molecular representations of facts such as Man(Socrates) and rules such as Mortal(X) logical deductions and delivers the result. This prototype is the first simple programming language with a molecular-scale implementation.

  13. pyhector: A Python interface for the simple climate model Hector

    Energy Technology Data Exchange (ETDEWEB)

    N Willner, Sven; Hartin, Corinne; Gieseke, Robert

    2017-04-01

    Pyhector is a Python interface for the simple climate model Hector (Hartin et al. 2015) developed in C++. Simple climate models like Hector can, for instance, be used in the analysis of scenarios within integrated assessment models like GCAM1, in the emulation of complex climate models, and in uncertainty analyses. Hector is an open-source, object oriented, simple global climate carbon cycle model. Its carbon cycle consists of a one pool atmosphere, three terrestrial pools which can be broken down into finer biomes or regions, and four carbon pools in the ocean component. The terrestrial carbon cycle includes primary production and respiration fluxes. The ocean carbon cycle circulates carbon via a simplified thermohaline circulation, calculating air-sea fluxes as well as the marine carbonate system (Hartin et al. 2016). The model input is time series of greenhouse gas emissions; as example scenarios for these the Pyhector package contains the Representative Concentration Pathways (RCPs)2. These were developed to cover the range of baseline and mitigation emissions scenarios and are widely used in climate change research and model intercomparison projects. Using DataFrames from the Python library Pandas (McKinney 2010) as a data structure for the scenarios simplifies generating and adapting scenarios. Other parameters of the Hector model can easily be modified when running the model. Pyhector can be installed using pip from the Python Package Index.3 Source code and issue tracker are available in Pyhector's GitHub repository4. Documentation is provided through Readthedocs5. Usage examples are also contained in the repository as a Jupyter Notebook (Pérez and Granger 2007; Kluyver et al. 2016). Courtesy of the Mybinder project6, the example Notebook can also be executed and modified without installing Pyhector locally.

  14. Global health research needs global networking

    NARCIS (Netherlands)

    Ignaciuk, A.; Leemans, R.

    2012-01-01

    To meet the challenges arising from global environmental change on human health, co-developing common approaches and new alliances of science and society are necessary. The first steps towards defining cross-cutting, health-environment issues were developed by the Global Environmental Change and

  15. A real-time Global Warming Index.

    Science.gov (United States)

    Haustein, K; Allen, M R; Forster, P M; Otto, F E L; Mitchell, D M; Matthews, H D; Frame, D J

    2017-11-13

    We propose a simple real-time index of global human-induced warming and assess its robustness to uncertainties in climate forcing and short-term climate fluctuations. This index provides improved scientific context for temperature stabilisation targets and has the potential to decrease the volatility of climate policy. We quantify uncertainties arising from temperature observations, climate radiative forcings, internal variability and the model response. Our index and the associated rate of human-induced warming is compatible with a range of other more sophisticated methods to estimate the human contribution to observed global temperature change.

  16. Globalization of nuclear activities and global governance

    International Nuclear Information System (INIS)

    Sefidvash, Farhang

    1997-01-01

    The safe production of nuclear energy as well as the disarmament of nuclear weapons and the peaceful utilization of nuclear materials resulting from dismantling of such weapons are some of the formidable problems of global governance. The Commission on Global Governance was established in 1992 in the belief that international developments had created a unique opportunity for strengthening global co-operation to meet the challenge of securing peace, achieving sustainable development, and universalizing democracy. Here a summary of their proposals on the globalization of nuclear activities to face challenges of the coming century is given. To follow up their activities by the worlds community in general. The research Centre for Global Governance (RCGG) at the Federal University of Rio Grande do Sul was established. Already a great number of researchers from many different countries have adhered to the Centre. Here the program of the RCGG is described. (author)

  17. Globalization of nuclear activities and global governance

    Energy Technology Data Exchange (ETDEWEB)

    Sefidvash, Farhang [Rio Grande do Sul Univ., Porto Alegre, RS (Brazil). Dept. de Engenharia Nuclear

    1997-07-01

    The safe production of nuclear energy as well as the disarmament of nuclear weapons and the peaceful utilization of nuclear materials resulting from dismantling of such weapons are some of the formidable problems of global governance. The Commission on Global Governance was established in 1992 in the belief that international developments had created a unique opportunity for strengthening global co-operation to meet the challenge of securing peace, achieving sustainable development, and universalizing democracy. Here a summary of their proposals on the globalization of nuclear activities to face challenges of the coming century is given. To follow up their activities by the worlds community in general. The research Centre for Global Governance (RCGG) at the Federal University of Rio Grande do Sul was established. Already a great number of researchers from many different countries have adhered to the Centre. Here the program of the RCGG is described. (author)

  18. A single variable shear deformable nonlocal theory for transversely ...

    Indian Academy of Sciences (India)

    Rameshchandra P Shimpi

    2018-05-11

    May 11, 2018 ... Abstract. In this paper, a simple single variable shear deformable nonlocal theory for bending of micro- and ... the models based upon continuum mechanics are widely .... of the body. ...... Elsevier Science Ltd, Oxford, UK. pp.

  19. Simple Approach to Superamphiphobic Overhanging Silicon Nanostructures

    DEFF Research Database (Denmark)

    Kumar, Rajendra; Mogensen, Klaus Bo; Bøggild, Peter

    2010-01-01

    with contact angles up to 152 degrees and roll-off angle down to 8 degrees. Such nonlithographic nanoscale overhanging Structures can also be added to silicon nanograss by deposition of a thin SiO2 layer, which equips the silicon rods with 100-300 nm sized overhanging Structures. This is a simple, fast...

  20. Question Answering for Dutch : Simple does it

    NARCIS (Netherlands)

    Hoekstra, A.H.; Hiemstra, Djoerd; van der Vet, P.E.; Huibers, Theo W.C.; Schobbens, Pierre-Yves; Vanhoof, Wim; Schwanen, Gabriel

    2006-01-01

    When people pose questions in natural language to search for information on the web, the role of question answering (QA) systems becomes important. In this paper the QAsystem simpleQA, capable of answering Dutch questions on which the answer is a person or a location, is described. The system's

  1. Nature versus Nurture: The Simple Contrast

    Science.gov (United States)

    Davidoff, Jules; Goldstein, Julie; Roberson, Debi

    2009-01-01

    We respond to the commentary of Franklin, Wright, and Davies ("Journal of Experimental Child Psychology, 102", 239-245 [2009]) by returning to the simple contrast between nature and nurture. We find no evidence from the toddler data that makes us revise our ideas that color categories are learned and never innate. (Contains 1 figure.)

  2. Simple picture of the annihilation process

    International Nuclear Information System (INIS)

    Gotsman, E.; Nussinov, S.

    1980-01-01

    We propose a simple geometrical picture for B-barB annihilations, which is motivated by the electric-flux-tube model and is consistent with the quark-rearrangement model, as well as the nonplanar multiperipheral quark-exchange model. Within its framework we are able to explain all the salient features of the experimental annihilation data

  3. Simple Analysis of Historical Lime Mortars

    Science.gov (United States)

    Pires, Joa~o

    2015-01-01

    A laboratory experiment is described in which a simple characterization of a historical lime mortar is made by the determination of its approximate composition by a gravimetric method. Fourier transform infrared (FTIR) spectroscopy and X-ray diffraction (XRD) are also used for the qualitative characterization of the lime mortar components. These…

  4. Seismic Safety Of Simple Masonry Buildings

    International Nuclear Information System (INIS)

    Guadagnuolo, Mariateresa; Faella, Giuseppe

    2008-01-01

    Several masonry buildings comply with the rules for simple buildings provided by seismic codes. For these buildings explicit safety verifications are not compulsory if specific code rules are fulfilled. In fact it is assumed that their fulfilment ensures a suitable seismic behaviour of buildings and thus adequate safety under earthquakes. Italian and European seismic codes differ in the requirements for simple masonry buildings, mostly concerning the building typology, the building geometry and the acceleration at site. Obviously, a wide percentage of buildings assumed simple by codes should satisfy the numerical safety verification, so that no confusion and uncertainty have to be given rise to designers who must use the codes. This paper aims at evaluating the seismic response of some simple unreinforced masonry buildings that comply with the provisions of the new Italian seismic code. Two-story buildings, having different geometry, are analysed and results from nonlinear static analyses performed by varying the acceleration at site are presented and discussed. Indications on the congruence between code rules and results of numerical analyses performed according to the code itself are supplied and, in this context, the obtained result can provide a contribution for improving the seismic code requirements

  5. Bayesian decision theory : A simple toy problem

    NARCIS (Netherlands)

    van Erp, H.R.N.; Linger, R.O.; van Gelder, P.H.A.J.M.

    2016-01-01

    We give here a comparison of the expected outcome theory, the expected utility theory, and the Bayesian decision theory, by way of a simple numerical toy problem in which we look at the investment willingness to avert a high impact low probability event. It will be found that for this toy problem

  6. Low Cost, Simple, Intrauterine Insemination Procedure with ...

    African Journals Online (AJOL)

    During the last 30 years however, intrauterine insemination has evolved with the introduction of ovulation stimulating protocols and sperm preparation methods taken from assisted reproduction techniques. Costs have risen, but the success rate has not risen to the same extent. We have therefore developed a quite simple ...

  7. A rewriting view of simple typing

    NARCIS (Netherlands)

    Stump, A.; Zantema, H.; Kimmell, G.; El Haj Omar, R.

    2013-01-01

    This paper shows how a recently developed view of typing as small-step abstract reduction, due to Kuan, MacQueen, and Findler, can be used to recast the development of simple type theory from a rewriting perspective. We show how standard meta-theoretic results can be proved in a completely new way,

  8. Studying the Greenhouse Effect: A Simple Demonstration.

    Science.gov (United States)

    Papageorgiou, G.; Ouzounis, K.

    2000-01-01

    Studies the parameters involved in a presentation of the greenhouse effect and describes a simple demonstration of this effect. Required equipment includes a 100-120 watt lamp, a 250mL beaker, and a thermometer capable of recording 0-750 degrees Celsius together with a small amount of chloroform. (Author/SAH)

  9. Simple parametrization of nucleon form factors

    International Nuclear Information System (INIS)

    Kelly, J.J.

    2004-01-01

    This Brief Report provides simple parametrizations of the nucleon electromagnetic form factors using functions of Q 2 that are consistent with dimensional scaling at high Q 2 . Good fits require only four parameters each for G Ep , G Mp , and G Mn and only two for G En

  10. A Simple Sketch Symbolizing Self-Reliance

    Centers for Disease Control (CDC) Podcasts

    2017-02-16

    EID Managing Editor, Byron Breedlove, reads his cover art story, A Simple Sketch Symbolizing Self-Reliance.  Created: 2/16/2017 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 2/16/2017.

  11. Simple Cloud Chambers Using Gel Ice Packs

    Science.gov (United States)

    Kamata, Masahiro; Kubota, Miki

    2012-01-01

    Although cloud chambers are highly regarded as teaching aids for radiation education, school teachers have difficulty in using cloud chambers because they have to prepare dry ice or liquid nitrogen before the experiment. We developed a very simple and inexpensive cloud chamber that uses the contents of gel ice packs which can substitute for dry…

  12. A Study of Simple Diffraction Models

    DEFF Research Database (Denmark)

    Agerkvist, Finn

    In this paper two simple methods for cabinet edge diffraction are examined. Calculations with both models are compared with more sophisticated theoretical models and with measured data. The parameters involved are studied and their importance for normal loudspeaker box designs is examined....

  13. Variations on a Simple Dice Game

    Science.gov (United States)

    Heafner, Joe

    2018-01-01

    I begin my introductory astronomy course with a unit on critical thinking that focuses on, among other things, the differences between the "scientific method" as frequently presented in textbooks and actual scientific practice. One particular classroom activity uses a simple dice game to simulate observation of a natural phenomenon and…

  14. Tour of a Simple Trigonometry Problem

    Science.gov (United States)

    Poon, Kin-Keung

    2012-01-01

    This article focuses on a simple trigonometric problem that generates a strange phenomenon when different methods are applied to tackling it. A series of problem-solving activities are discussed, so that students can be alerted that the precision of diagrams is important when solving geometric problems. In addition, the problem-solving plan was…

  15. A rewriting view of simple typing

    NARCIS (Netherlands)

    Stump, A.; Zantema, H.; Kimmell, G.; El Haj Omar, R.

    2012-01-01

    This paper shows how a recently developed view of typing as small-step abstract reduction, due to Kuan, MacQueen, and Findler, can be used to recast the development of simple type theory from a rewriting perspective. We show how standard meta-theoretic results can be proved in a completely new way,

  16. A simple model for indentation creep

    Science.gov (United States)

    Ginder, Ryan S.; Nix, William D.; Pharr, George M.

    2018-03-01

    A simple model for indentation creep is developed that allows one to directly convert creep parameters measured in indentation tests to those observed in uniaxial tests through simple closed-form relationships. The model is based on the expansion of a spherical cavity in a power law creeping material modified to account for indentation loading in a manner similar to that developed by Johnson for elastic-plastic indentation (Johnson, 1970). Although only approximate in nature, the simple mathematical form of the new model makes it useful for general estimation purposes or in the development of other deformation models in which a simple closed-form expression for the indentation creep rate is desirable. Comparison to a more rigorous analysis which uses finite element simulation for numerical evaluation shows that the new model predicts uniaxial creep rates within a factor of 2.5, and usually much better than this, for materials creeping with stress exponents in the range 1 ≤ n ≤ 7. The predictive capabilities of the model are evaluated by comparing it to the more rigorous analysis and several sets of experimental data in which both the indentation and uniaxial creep behavior have been measured independently.

  17. Simple Calculation Programs for Biology Other Methods

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Simple Calculation Programs for Biology Other Methods. Hemolytic potency of drugs. Raghava et al., (1994) Biotechniques 17: 1148. FPMAP: methods for classification and identification of microorganisms 16SrRNA. graphical display of restriction and fragment map of ...

  18. Simple model of the arms race

    International Nuclear Information System (INIS)

    Zane, L.I.

    1982-01-01

    A simple model of a two-party arms race is developed based on the principle that the race will continue so long as either side can unleash an effective first strike against the other side. The model is used to examine how secrecy, the ABM, MIRV-ing, and an MX system affect the arms race

  19. Microwave Radiometer Linearity Measured by Simple Means

    DEFF Research Database (Denmark)

    Skou, Niels

    2002-01-01

    Modern spaceborne radiometer systems feature an almost perfect on-board calibration, hence the primary calibration task to be carried out before launch is a check of radiometer linearity. This paper describes two ways of measuring linearity of microwave radiometers only requiring relatively simple...

  20. Simple Calculation Programs for Biology Immunological Methods

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Simple Calculation Programs for Biology Immunological Methods. Computation of Ab/Ag Concentration from EISA data. Graphical Method; Raghava et al., 1992, J. Immuno. Methods 153: 263. Determination of affinity of Monoclonal Antibody. Using non-competitive ...