WorldWideScience

Sample records for single research booth

  1. Photobiological evaluation of tanning booths

    International Nuclear Information System (INIS)

    Nachtwey, D.S.; Rundel, R.D.

    1981-01-01

    The use of tanning booths as a substitute for natural sunlight is becoming increasingly popular. However, unless careful attention is paid to proper design and maintenance, the radiation field inside a tanning booth can be highly anisotropic. The use of simple, inexpensive ultraviolet radiation meters to measure dosage can lead to serious overexposure. Since the ultraviolet radiation inside a tanning booth has a greater proportion of short wavelengths (less than 300 nanometers) than natural sunlight, the amount of skin cancer-inducing radiation received for a tan may be twice that received for a natural suntan

  2. Springer Publishing Booth | 4-5 October

    CERN Multimedia

    2016-01-01

    In the spirit of continuation of the CERN Book Fairs of the past years, Springer Nature will be present with a book and journal booth on October 4th and 5th, located as usual in the foyer of the Main Building. Some of the latest titles in particle physics and related fields will be on sale.   You are cordially invited to come to the booth to meet Heike Klingebiel (Licensing Manager / Library Sales), Hisako Niko (Publishing Editor) and Christian Caron (Publishing Editor). In particular, information about the new Nano database – nanomaterial and device profiles from high-impact journals and patents, manually abstracted, curated and updated by nanotechnology experts – will be available. The database is accessible here: http://nano.nature.com/. 

  3. Anthropometric data collection of Portuguese children using 3D body scanning: considerations about the scanning booth

    Science.gov (United States)

    de Campos, R.; Carvalho, M. A.; Lopes, H. P.; Xu, B.

    2017-10-01

    This paper presents some considerations regarding the scanning booth used in an anthropometric study done with a 3D body scanning technology. The data collected is part of a Ph.D. study conducted in Textile Engineering at University of Minho in Portugal, which aims to develop clothing for overweight and obese Portuguese children aged 2-11 years, of both genders. The challenges faced during data collection are described, and modifications of the scanning booth are proposed. It is possible to conclude that the importance of the scanning booth is key to an efficient anthropometric data collection, including the growth of this technology in the garment industry, Universities Research Institutes involved with anthropometric studies.

  4. Environmental lead exposure to toll booth workers in Hong Kong

    Energy Technology Data Exchange (ETDEWEB)

    Tan, T.C.; Wong, L.T.L.; Lam, C.W.K. (Chinese Univ. of Hong Kong, Shatin)

    1988-01-01

    A survey of workers in the Lion Rock Tunnel toll booths was conducted, as they were regarded as a high risk group in lead exposure due to high density of vehicular traffic. The exposure of the workers to lead was determined by continuous sapling of air around the breathing zone of workers inside the booths. Blood lead concentration of 50 workers showed a mean of 0.65 {mu}mol/L and the mean urine lead concentration was 0.14 {mu}mol/L. Other tests, such as urinary amino-levulinic acid (ALA), erythrocyte zinc protoporphyrin (ZnPP) and hemoglobin concentration (Hb), were also preformed. The blood lead concentrations and other biological parameters of the toll-booth workers were acceptable and may be attributed to the recent legislation to lower the lead content in petrol and to the good preventive measures taken by the management.

  5. Digital Unbounding of the Polling Booth: Ethnography in Small Places

    DEFF Research Database (Denmark)

    Dalsgaard, Steffen; Gad, Christopher

    2017-01-01

    recently occurred in Denmark when the government proposed to digitalise voting. Digitalisation here became a controversy because of the potential illicit influences that computer experts argued would enter the polling booth and challenge the secrecy and the privacy of the vote, the transparency...

  6. Evaluation of VOC emission measurement methods for paint spray booths.

    Science.gov (United States)

    Eklund, B M; Nelson, T P

    1995-03-01

    Interest in regulations to control solvent emissions from automotive painting systems is increasing, especially in ozone nonattainment areas. Therefore, an accurate measurement method for VOC emissions from paint spray booths used in the automotive industry is needed to ascertain the efficiency of the spray booth capture and the total emissions. This paper presents the results of a laboratory study evaluating potential VOC sampling and analytical methods used in estimating paint spray booth emissions, and discusses these results relative to other published data. Eight test methods were selected for evaluation. The accuracy of each sampling and analytical method was determined using test atmospheres of known concentration and composition that closely matched the actual exhaust air from paint spray booths. The solvent mixture to generate the test atmospheres contained a large proportion of polar, oxygenated hydrocarbons such as ketones and alcohols. A series of identical tests was performed for each sampling/analytical method with each test atmosphere to assess the precision of the methods. The study identified significant differences among the test methods in terms of accuracy, precision, cost, and complexity.

  7. PAINT SPRAY BOOTH DESIGN USING RECIRCULATION/PARTITIONING VENTILATION

    Science.gov (United States)

    Many spray painting facility operators have been attempting to reduce the discharge of volatile organic compounds (VOCs) from paint spray booths to the atmosphere. Some have been able to convert to lower VOC containing paints and coatings such as powder coating, waterborne coatin...

  8. An Efficient 16-Bit Multiplier based on Booth Algorithm

    Science.gov (United States)

    Khan, M. Zamin Ali; Saleem, Hussain; Afzal, Shiraz; Naseem, Jawed

    2012-11-01

    Multipliers are key components of many high performance systems such as microprocessors, digital signal processors, etc. Optimizing the speed and area of the multiplier is major design issue which is usually conflicting constraint so that improving speed results mostly in bigger areas. A VHDL designed architecture based on booth multiplication algorithm is proposed which not only optimize speed but also efficient on energy use.

  9. Ergonomic Assessment and Design of Electronic Ticket Booths in Mashhad City

    Directory of Open Access Journals (Sweden)

    H. Razavi

    2015-04-01

    .Conclusion: Vendors of electronic ticket booths are exposed to musculoskeletal and environmental health threats, in Mashhad. Relocating the booths, adjustingcounterand desk height can significantly reduce the risk of mentioned hazards

  10. Springer Publishing book booth | 8-9 October

    CERN Multimedia

    CERN Library

    2015-01-01

    Continuing the spirit of the CERN Book Fairs of the past years, Springer Publishing will have a book booth in the foyer of the Main Building, from 8 to 9 October. Some of the latest titles in particle physics and related fields will be on sale.   For the occasion, Professor Ugo Amaldi will present his new book “Particle Accelerators: From Big Bang Physics to Hadron Therapy” on Thursday, 8 October at 5 p.m. in Room F (Charpak room). The presentation will take place in the framework of the Italian Teachers week and will be followed by a signing session. A special highlight at the Springer booth will be the presentation of the CERN-sponsored Open Access book: “J Rafelski (ed): Melting Hadrons, Boiling Quarks - From Hagedorn Temperature to Ultra-Relativistic Heavy-Ion Collisions at CERN; With a Tribute to Rolf Hagedorn”.

  11. Performance evaluation of mobile downflow booths for reducing airborne particles in the workplace.

    Science.gov (United States)

    Lo, Li-Ming; Hocker, Braden; Steltz, Austin E; Kremer, John; Feng, H Amy

    2017-11-01

    Compared to other common control measures, the downflow booth is a costly engineering control used to contain airborne dust or particles. The downflow booth provides unidirectional filtered airflow from the ceiling, entraining released particles away from the workers' breathing zone, and delivers contained airflow to a lower level exhaust for removing particulates by filtering media. In this study, we designed and built a mobile downflow booth that is capable of quick assembly and easy size change to provide greater flexibility and particle control for various manufacturing processes or tasks. An experimental study was conducted to thoroughly evaluate the control performance of downflow booths used for removing airborne particles generated by the transfer of powdered lactose between two containers. Statistical analysis compared particle reduction ratios obtained from various test conditions including booth size (short, regular, or extended), supply air velocity (0.41 and 0.51 m/s or 80 and 100 feet per minute, fpm), powder transfer location (near or far from the booth exhaust), and inclusion or exclusion of curtains at the booth entrance. Our study results show that only short-depth downflow booths failed to protect the worker performing powder transfer far from the booth exhausts. Statistical analysis shows that better control performance can be obtained with supply air velocity of 0.51 m/s (100 fpm) than with 0.41 m/s (80 fpm) and that use of curtains for downflow booths did not improve their control performance.

  12. The Utility of Single Subject Design Research

    Science.gov (United States)

    Bennett, Kyle D.

    2016-01-01

    Single subject design (SSD) research is a quantitative approach used to investigate basic and applied research questions. It has been used for decades to examine issues of social importance such as those related to general and special education strategies, therapeutic approaches in mental health, community health practices, safety, and business…

  13. Estimating personal exposures based on mass balance material usage rates: validation of a ventilation model in a spray paint booth.

    Science.gov (United States)

    Taylor, Jon R; O'Shaughnessy, Patrick T; Reynolds, Stephen J

    2004-04-01

    The goal of this research was to evaluate an estimating model (box model) with direct measurements of contaminants in an industrial spray painting operation. The research involved a dilution ventilation efficiency experiment that was devised to estimate the effective ventilation rate, sampling for organic compounds (xylene, ethyl benzene, methyl ethyl ketone, and methyl isobutyl ketone) in a paint booth, and simultaneously measuring the mass usage of these compounds during painting operations in order to compare measured with predicted concentrations. The results of the dilution ventilation experiment indicated that channeling of air was occurring due to a high ventilation rate in the painting area. The results of the mass balance usage and air sampling comparisons indicated that predicted concentrations were within the 95% upper/lower confidence interval about the geometric mean in 14 out of 16 area samples taken within the paint booth (87.5%). Correlation analysis between predicted concentrations and area, personal, and exhaust stack concentrations were strongest with exhaust (r = 0.923). Correlations with personal concentrations were not as strong (r = 0.828), and the area concentrations were even less strong (0.757). In conclusion, the box model does appear to be a useful additional tool for estimating worker exposures. However, the characteristics of any particular ventilation system must be understood before modeling is conducted.

  14. Extension of Tom Booth's Modified Power Method for Higher Eigen Modes

    International Nuclear Information System (INIS)

    Zhang, Peng; Lee, Hyunsuk; Lee, Deokjung

    2015-01-01

    A possible technique to get the even higher modes is suggested, but it is difficult to be applied practically. In this paper, a general solution strategy is proposed, which can extend Tom Booth's modified power method to get the higher Eigenmodes and there is no limitation about the number of Eigenmodes that can be obtained with this method. In this paper, a general solution strategy is proposed, which can extend Tom Booth's modified power method to get the higher Eigenmodes and there is no limitation about the number of Eigenmodes that can be obtained with this method. It is more practical than the original solution strategy that Tom Booth proposed. The implementation of the method in Monte Carlo code shows significant advantages comparing to the original power method

  15. London through Rose-Colored Graphics: Visual Rhetoric and Information Graphic Design in Charles Booth's Maps of London Poverty

    Science.gov (United States)

    Kimball, Miles A.

    2006-01-01

    In this article, I examine a historical information graphic--Charles Booth's maps of London poverty (1889-1902)--to analyze the cultural basis of ideas of transparency and clarity in information graphics. I argue that Booth's maps derive their rhetorical power from contemporary visual culture as much as from their scientific authority. The visual…

  16. The Art of Being Persuaded: Wayne Booth's Mutual Inquiry and the Trust to Listen

    Science.gov (United States)

    Baker, Marsha Lee; Dieter, Eric; Dobbins, Zachary

    2014-01-01

    This article examines Wayne C. Booth's legacy as a teacher and scholar through the concept of rhetoric as mutual inquiry that he develops from "Modern Dogma and the Rhetoric of Assent" (1974) through "The Rhetoric of Rhetoric" (2004). Booth's work connects the political and pedagogical in pragmatic and productive ways…

  17. USERS GUIDE FOR THE CONVERSION OF NAVY PAINT SPRAY BOOTH PARTICULATE EMISSION CONTROL SYSTEMS FROM WET TO DRY OPERATION

    Science.gov (United States)

    The report is a guide or convrting U.S. Navy paint spray booth particulate emission control systems from wet to dry operation. The use of water curtains for air pollution control of paint spray booths is considered a major source of water and solid waste pol-lution from industria...

  18. In Tune with Play and Therapy an Interview with Phyllis Booth

    Science.gov (United States)

    American Journal of Play, 2015

    2015-01-01

    Phyllis Booth is a licensed marriage and family therapist, a licensed clinical professional counselor, a registered play therapist and supervisor, and Clinical Director Emeritus of the Theraplay Institute in Evanston, Illinois. Her professional career includes training in clinical psychology at what is now University of Chicago Medicine, teaching…

  19. COST EFFECTIVE VOC EMISSION CONTROL STARTEGIES FOR MILITARY, AEROSPACE,AND INDUSTRIAL PAINT SPRAY BOOTH OPERATIONS: COMBINING IMPROVED VENTILATION SYSTEMS WITH INNOVATIVE, LOW COST EMISSION CONTROL TECHNOLOGIES

    Science.gov (United States)

    The paper describes a full-scale demonstration program in which several paint booths were modified for recirculation ventilation; the booth exhaust streams are vented to an innovative volatile organic compound (VOC) emission control system having extremely low operating costs. ...

  20. Booth Revisited: Identifying the Determinants of Capital Structure in the Sugar Sector

    Directory of Open Access Journals (Sweden)

    A.A. Kanwar

    2007-07-01

    Full Text Available The study assesses whether selected exogenous variables: tax rate, size, asset tangibility, volatility and profitability, affect capital structure in a significant manner in the sugar industry. It suggests that decision on capital structuring is found to be weakly affected by the variables chosen in our study. This is also consistent with the results of Booth et al (2001 where modern financial theory is found to be weakly portable across a group of developed and developing countries. It is recommended that more empirical work is done in order to understand the impact of capital structure choices.

  1. Effect Sizes in Single Case Research: How Large is Large?

    Science.gov (United States)

    Parker, Richard I.; Brossart, Daniel F.; Vannest, Kimberly J.; Long, James R.; De-Alba, Roman Garcia; Baugh, Frank G.; Sullivan, Jeremy R.

    2005-01-01

    This study examined the problem of interpreting effect sizes in single case research. Nine single case analytic techniques were applied to a convenience sample of 77 published interrupted time series (AB) datasets, and the results were compared by technique across the datasets. Reanalysis of the published data helped answer questions about the…

  2. Size distribution of chromate paint aerosol generated in a bench-scale spray booth.

    Science.gov (United States)

    Sabty-Daily, Rania A; Hinds, William C; Froines, John R

    2005-01-01

    Spray painters are potentially exposed to aerosols containing hexavalent chromium [Cr(VI)] via inhalation of chromate-based paint sprays. Evaluating the particle size distribution of a paint spray aerosol, and the variables that may affect this distribution, is necessary to determine the site and degree of respiratory deposition and the damage that may result from inhaled Cr(VI)-containing paint particles. This study examined the effect of spray gun atomization pressure, aerosol generation source and aerosol aging on the size distribution of chromate-based paint overspray aerosols generated in a bench-scale paint spray booth. The study also determined the effect of particle bounce inside a Marple personal cascade impactor on measured size distributions of paint spray aerosols. Marple personal cascade impactors with a modified inlet were used for sample collection. The data indicated that paint particle bounce did not occur inside the cascade impactors sufficiently to affect size distribution when using uncoated stainless steel or PVC substrate sampling media. A decrease in paint aerosol mass median aerodynamic diameter (MMAD) from 8.2 to 7.0 mum was observed as gun atomization pressure increased from 6 to 10 psi. Overspray aerosols were sampled at two locations in the spray booth. A downstream sampling position simulated the exposure of a worker standing between the painted surface and exhaust, a situation encountered in booths with multiple workers. The measured mean MMAD was 7.2 mum. The distance between the painted surface and sampler was varied to sample oversprays of varying ages between 2.8 and 7.7 s. Age was not a significant factor for determining MMAD. Overspray was sampled at a 90 degrees position to simulate a worker standing in front of the surface being painted with air flowing to the worker's side, a common situation in field applications. The resulting overspray MMAD averaged 5.9 mum. Direct-spray aerosols were sampled at ages from 5.3 to 11.7 s

  3. Users Guide for the Conversion of Navy Paint Spray Booth Particulate Emission Control Systems from Wet to Dry Operation

    Science.gov (United States)

    1990-06-01

    filter system or contacting flter vendors, a complete equipment audit must be performed to determine booth system characteristics. Information regarding...media is composed of specially designed woven or nonwoven cloth. It is available in thicknesses ranging from 0.25 to 1 inch, and in pads or rolls up to

  4. Hundreds of Area Residents Visit the National Lab Booth at the Annual In The Street Festival | Poster

    Science.gov (United States)

    Light-up yo-yos, brightly colored portion plates, and a fast spinner game lured hundreds of area residents to the Frederick National Lab booth at this year’s In The Street festival, where they also heard a message from the lab: Stay healthy through healthy habits.

  5. Single-participant research design. Bringing science to managed care.

    Science.gov (United States)

    Morgan, D L; Morgan, R K

    2001-02-01

    The ongoing transition to managed health care continues to have repercussions for health care providers, perhaps the most important of which is an emphasis on accountability for demonstrating the usefulness of clinical interventions. This requirement places a premium on intervention research and highlights the historically strained relationship between psychological research and professional practice. In the midst of this challenge, researchers have increasingly criticized the logic and practice of traditional null hypothesis significance testing. This article describes the history, epistemology, and advantages of single-participant research designs for behavioral scientists and professionals in clinical settings. Although its lack of correspondence with the Fisherian tradition has precluded widespread adoption, the single-participant alternative features a design power and flexibility well suited to both basic science and applied research.

  6. The Applied Behavior Analysis Research Paradigm and Single-Subject Designs in Adapted Physical Activity Research.

    Science.gov (United States)

    Haegele, Justin A; Hodge, Samuel Russell

    2015-10-01

    There are basic philosophical and paradigmatic assumptions that guide scholarly research endeavors, including the methods used and the types of questions asked. Through this article, kinesiology faculty and students with interests in adapted physical activity are encouraged to understand the basic assumptions of applied behavior analysis (ABA) methodology for conducting, analyzing, and presenting research of high quality in this paradigm. The purposes of this viewpoint paper are to present information fundamental to understanding the assumptions undergirding research methodology in ABA, describe key aspects of single-subject research designs, and discuss common research designs and data-analysis strategies used in single-subject studies.

  7. Single cell analysis contemporary research and clinical applications

    CERN Document Server

    Cossarizza, Andrea

    2017-01-01

    This book highlights the current state of the art in single cell analysis, an area that involves many fields of science – from clinical hematology, functional analysis and drug screening, to platelet and microparticle analysis, marine biology and fundamental cancer research. This book brings together an eclectic group of current applications, all of which have a significant impact on our current state of knowledge. The authors of these chapters are all pioneering researchers in the field of single cell analysis. The book will not only appeal to those readers more focused on clinical applications, but also those interested in highly technical aspects of the technologies. All of the technologies identified utilize unique applications of photon detection systems.

  8. EVALUATION OF INNOVATIVE VOLATILE ORGANIC COMPOUND AND HAZARDOUS AIR POLLUTANT CONTROL TECHNOLOGIES FOR U.S. AIR FORCE PAINT SPRAY BOOTHS

    Science.gov (United States)

    This report gives results of an evaluation of carbon paper adsorption catalytic incineration (CPACI) and fluidized-bed catalytic incineration (FBCI) as control technologies to reduce volatile organic compound (VOC) emissions from paint spray booths.

  9. Gravity research on plants: use of single cell experimental models

    Directory of Open Access Journals (Sweden)

    Youssef eChebli

    2011-09-01

    Full Text Available Future space missions and implementation of permanent bases on Moon and Mars will greatly depend on the availability of ambient air and sustainable food supply. Therefore, understanding the effects of altered gravity conditions on plant metabolism and growth is vital for space missions and extra-terrestrial human existence. In this mini-review we summarize how plant cells are thought to perceive changes in magnitude and orientation of the gravity vector. The particular advantages of several single celled model systems for gravity research are explored and an overview over recent advancements and potential use of these systems is provided.

  10. The Use of Single-Subject Research to Identify Evidence-Based Practice in Special Education

    Science.gov (United States)

    Horner, Robert H.; Carr, Edward G.; Halle, James; McGee, Gail; Odom, Samuel; Wolery, Mark

    2005-01-01

    Single-subject research plays an important role in the development of evidence-based practice in special education. The defining features of single-subject research are presented, the contributions of single-subject research for special education are reviewed, and a specific proposal is offered for using single-subject research to document…

  11. An overview on single nucleotide polymorphism studies in mastitis research

    Directory of Open Access Journals (Sweden)

    V. N. Muhasin Asaf

    2014-06-01

    Full Text Available Mastitis is an inflammatory condition of the mammary gland caused by microorganisms as diverse as bacteria, viruses, mycoplasma, yeasts and algae. Mastitis is an economically devastating disease mainly affecting the crossbred cattle in India. Control strategies against mastitis includes antibiotic therapy, vaccination, improvements in dairy cattle husbandry, farm and feeding management etc. but has met with little success.. Mastitis tolerance/susceptibility is difficult to measure directly and hence milk somatic cell count (SCC or milk somatic cell score (SCS is used as an indicator trait for mastitis as both traits are highly positively correlated. Single nucleotide polymorphism (SNP marker is a single base change in a DNA sequence at a given position. SNP markers are the most preferred genetic markers nowadays. Currently most researches worldwide have been targeting molecular high density SNP markers that are linked to mastitis tolerance in an attempt to incorporate to understand the genetics of host resistance to mastitis and this knowledge will be helpful in formulating breeding programmes in an attempt to control mastitis. This article reviews various SNPs which are reported to be significantly associated with mastitis tolerance/susceptibility.

  12. The Old Man and the Glass Booth: Adolf Eichmann and the Migration of an Under- and Overdetermined Iconography

    Directory of Open Access Journals (Sweden)

    Matthias Steinle

    2015-07-01

    Full Text Available This article discusses the image of Adolf Eichmann, which has haunted the screen ever since his spectacular kidnapping in Argentina. Characterized by a lack of archive images from the Nazi era and an abundance of images from the trial in Jerusalem in 1962, the man in the glass booth is an interesting example of the role of archive images in cultural memory and the mediality of history. Eichmann as a “media phenomenon” is analysed in his different dimensions: first a semiologic study of the two iconic images which became “super signs” of the Holocaust, generating contradictory narratives; then an exhaustive overview of the films produced about Adolf Eichmann with their thematic and narrative approaches; the analysis of three films made after the Fall of the Berlin Wall and their link to German national memory; and finally a discussion of the central motive of the glass booth and its migration toward other filmic contexts, giving Eichmann a wider presence in popular culture.

  13. Research highlights: microfluidic-enabled single-cell epigenetics.

    Science.gov (United States)

    Dhar, Manjima; Khojah, Reem; Tay, Andy; Di Carlo, Dino

    2015-11-07

    Individual cells are the fundamental unit of life with diverse functions from metabolism to motility. In multicellular organisms, a single genome can give rise to tremendous variability across tissues at the single-cell level due to epigenetic differences in the genes that are expressed. Signals from the local environment or a history of signals can drive these variations, and tissues have many cell types that play separate roles. This epigenetic heterogeneity is of biological importance in normal functions such as tissue morphogenesis and can contribute to development or resistance of cancer, or other disease states. Therefore, an improved understanding of variations at the single cell level are fundamental to understanding biology and developing new approaches to combating disease. Traditional approaches to characterize epigenetic modifications of chromatin or the transcriptome of cells have often focused on blended responses of many cells in a tissue; however, such bulk measures lose spatial and temporal differences that occur from cell to cell, and cannot uncover novel or rare populations of cells. Here we highlight a flurry of recent activity to identify the mRNA profiles from thousands of single-cells as well as chromatin accessibility and histone marks on single to few hundreds of cells. Microfluidics and microfabrication have played a central role in the range of new techniques, and will likely continue to impact their further development towards routine single-cell epigenetic analysis.

  14. Single-Subject Research Methodology: An Underutilized Tool in the Field of Deafness.

    Science.gov (United States)

    Bullis, Michael; Anderson, Glenn

    1986-01-01

    Single-subject research methods are simple, powerful, and very applicable to selected study of deafness. This article considers group versus single-subject designs; an example of withdrawal single-subject design; and an example of the multiple baseline single-subject design. (CB)

  15. DEMONSTRATION OF A PAINT SPRAY BOOTH EMISSION CONTROL STRATEGY USING RECIRCULATION/PARTITIONING & UV/OZONE POLLUTION EMISSION CONTROL - VOLUME 1. TECHNICAL REPORT

    Science.gov (United States)

    The report describes in detail the source testing, construction, and data reduction/analysis activities that comprise the three phases of a technology demonstration program. Phase I consisted of a detailed baseline evaluation of several paint spray booths operated at the Barstow,...

  16. DEMONSTRATION OF SPLIT-FLOW VENTILATION AND RECIRCULATION AS FLOW-REDUCTION METHODS IN AN AIR FORCE PAINT SPRAY BOOTH - VOLUME II. APPENDICES D-J

    Science.gov (United States)

    During a series of painting operations in a horizontal-flow paint spray booth at Travis AFB, CA, baseline concentrations of four classes of toxic airborne pollutants were measured at 24 locations across a plane immediately forward of the exhaust filters, in the exhaust duct, and ...

  17. 40 CFR Appendix A to Subpart IIIi... - Determination of Capture Efficiency of Automobile and Light-Duty Truck Spray Booth Emissions From...

    Science.gov (United States)

    2010-07-01

    ... CATEGORIES National Emission Standards for Hazardous Air Pollutants: Surface Coating of Automobiles and Light... quickly to avoid further evaporation of VOC. The mass of the wet panel is represented by Wwet,i (grams). 2... area(s) or simulation of all of the flash-off area(s) located after the controlled spray booth zone or...

  18. Research status of large mode area single polarization active fiber

    Science.gov (United States)

    Xiao, Chun; Zhang, Ge; Yang, Bin-hua; Cheng, Wei-feng; Gu, Shao-yi

    2018-03-01

    As high power fiber laser used more and more widely, to increase the output power of fiber laser and beam quality improvement have become an important goal for the development of high power fiber lasers. The use of large mode fiber is the most direct and effective way to solve the nonlinear effect and fiber damage in the fiber laser power lifting process. In order to reduce the effect of polarization of the fiber laser system, the study found that when introduces a birefringence in the single-mode fiber, the polarization state changes caused by the birefringence is far greater than the random polarization state changes, then the external disturbance is completely submerged, finally the polarization can be controlled and stabilized. Through the fine design of the fiber structure, if the birefringence is high enough to achieve the separation of the two polarization states, the fiber will have a different cut-off mechanism to eliminate polarization which is not need, which will realize single mode single polarization transmission in a band. In this paper, different types of single polarization fiber design are presented and the application of these fibers are also discussed.

  19. Researchers propose single grade rule for evaluating hardwood pallet cants

    Science.gov (United States)

    Hal Mitchell; Marshall White; Philip Araman; Peter Hamner

    2008-01-01

    In "price taker" markets, successful businesses are the low cost producers, and pallet manufacturers are no exception. The single largest cost component of pallet manufacturing is raw material costs. Cants and lumber typically account for over 60% of operating costs. In the last three decades, cants have replaced lumber as the primary raw...

  20. Single-Subject Designs and Action Research in the K-12 Setting

    Science.gov (United States)

    Forbes, Sean A.; Ross, Margaret E.; Chesser, Svetlana S.

    2011-01-01

    In as much as educational research is concerned with individual student assessment and development, it is surprising that single-subject designs are not more readily utilized in classroom-based action research. The purpose of this article is to emphasize benefits of single-subject research in the K-12 setting, given that teachers teach and assess…

  1. The AI Interdisciplinary Context: Single or Multiple Research Bases?

    Science.gov (United States)

    Khawam, Yves J.

    1992-01-01

    This study used citation analysis to determine whether the disciplines contributing to the journal literature of artificial intelligence (AI)--philosophy, psychology, linguistics, computer science, and engineering--share a common AI research base. The idea that AI consists of a completely interdisciplinary endeavor was refuted. (MES)

  2. The single publication H-index and the indirect H-index of a researcher

    OpenAIRE

    Egghe, Leo

    2011-01-01

    The single publication H-index, introduced by A. Schubert in 2009 can be applied on all articles in the Hirsch-core of a researcher. In this way one can define the ‘‘indirect H-index’’ of a researcher. Single publication H-index; Indirect H-index

  3. An investigation of emotion experiences at work : a critical incident technique approach / Natalie Booth

    OpenAIRE

    Booth, Natalie

    2013-01-01

    Orientation: Emotions at work have been considered as an important facet of employees’ work life. However, research regarding the investigation of the emotion experiences at work per se has been lacking. Research Purpose: The general objective of this study is to critically investigate what emotion events are experienced and how these events are appraised for them to result in specific emotions. Motivation for the study: Currently a lack of research regarding emotion experiences as a pr...

  4. Single-Case Research Design: An Alternative Strategy for Evidence-Based Practice

    Science.gov (United States)

    Stapleton, Drue; Hawkins, Andrew

    2015-01-01

    Objective: The trend of utilizing evidence-based practice (EBP) in athletic training is now requiring clinicians, researchers, educators, and students to be equipped to both engage in and make judgments about research evidence. Single-case design (SCD) research may provide an alternative approach to develop such skills and inform clinical and…

  5. Studies Using Single-Subject Designs in Sport Psychology: 30 Years of Research

    Science.gov (United States)

    Martin, G. L.; Thompson, K.; Regehr, K.

    2004-01-01

    A prominent feature of behavior-analytic research has been the use of single-subject designs. We examined sport psychology journals and behavioral journals published during the past 30 years, and located 40 studies using single-subject designs to assess interventions for enhancing the performance of athletes and coaches. In this paper, we…

  6. Single-case research design in pediatric psychology: considerations regarding data analysis.

    Science.gov (United States)

    Cohen, Lindsey L; Feinstein, Amanda; Masuda, Akihiko; Vowles, Kevin E

    2014-03-01

    Single-case research allows for an examination of behavior and can demonstrate the functional relation between intervention and outcome in pediatric psychology. This review highlights key assumptions, methodological and design considerations, and options for data analysis. Single-case methodology and guidelines are reviewed with an in-depth focus on visual and statistical analyses. Guidelines allow for the careful evaluation of design quality and visual analysis. A number of statistical techniques have been introduced to supplement visual analysis, but to date, there is no consensus on their recommended use in single-case research design. Single-case methodology is invaluable for advancing pediatric psychology science and practice, and guidelines have been introduced to enhance the consistency, validity, and reliability of these studies. Experts generally agree that visual inspection is the optimal method of analysis in single-case design; however, statistical approaches are becoming increasingly evaluated and used to augment data interpretation.

  7. The Iterative Use of Single Case Research Designs to Advance the Science of EI/ECSE

    Science.gov (United States)

    Barton, Erin E.; Ledford, Jennifer R.; Lane, Justin D.; Decker, Jessica; Germansky, Sara E.; Hemmeter, Mary Louise; Kaiser, Ann

    2016-01-01

    Research in early intervention/early childhood special education (EI/ECSE) is focused on identifying effective practices related to positive outcomes for young children with disabilities and their families. Individual responses to evidence-based practices are often variable, and non-responders are common. Single case research (SCR) might be…

  8. OperaBooth

    DEFF Research Database (Denmark)

    Gelineck, Steven

    2014-01-01

    approaches have been taken to enhance the feeling of intimacy between the users of the installation. The paper describes related work within the field of mediated intimacy and musical interaction forming the initial goals of the system. It then describes the iterative development process, which includes two...... in the eye for an enhanced feeling of intimacy. Finally, a face-tracking algorithm detects when users open their mouth, which results in them triggering the voice of an opera singer. Thus, strangers (who are not musically skilled) are able to explore an opera-duet in a form of musical exploration...

  9. A Starting Point for Fluorescence-Based Single-Molecule Measurements in Biomolecular Research

    Directory of Open Access Journals (Sweden)

    Alexander Gust

    2014-09-01

    Full Text Available Single-molecule fluorescence techniques are ideally suited to provide information about the structure-function-dynamics relationship of a biomolecule as static and dynamic heterogeneity can be easily detected. However, what type of single-molecule fluorescence technique is suited for which kind of biological question and what are the obstacles on the way to a successful single-molecule microscopy experiment? In this review, we provide practical insights into fluorescence-based single-molecule experiments aiming for scientists who wish to take their experiments to the single-molecule level. We especially focus on fluorescence resonance energy transfer (FRET experiments as these are a widely employed tool for the investigation of biomolecular mechanisms. We will guide the reader through the most critical steps that determine the success and quality of diffusion-based confocal and immobilization-based total internal reflection fluorescence microscopy. We discuss the specific chemical and photophysical requirements that make fluorescent dyes suitable for single-molecule fluorescence experiments. Most importantly, we review recently emerged photoprotection systems as well as passivation and immobilization strategies that enable the observation of fluorescently labeled molecules under biocompatible conditions. Moreover, we discuss how the optical single-molecule toolkit has been extended in recent years to capture the physiological complexity of a cell making it even more relevant for biological research.

  10. Single-Case Experimental Designs: A Systematic Review of Published Research and Current Standards

    Science.gov (United States)

    Smith, Justin D.

    2013-01-01

    This article systematically reviews the research design and methodological characteristics of single-case experimental design (SCED) research published in peer-reviewed journals between 2000 and 2010. SCEDs provide researchers with a flexible and viable alternative to group designs with large sample sizes. However, methodological challenges have precluded widespread implementation and acceptance of the SCED as a viable complementary methodology to the predominant group design. This article includes a description of the research design, measurement, and analysis domains distinctive to the SCED; a discussion of the results within the framework of contemporary standards and guidelines in the field; and a presentation of updated benchmarks for key characteristics (e.g., baseline sampling, method of analysis), and overall, it provides researchers and reviewers with a resource for conducting and evaluating SCED research. The results of the systematic review of 409 studies suggest that recently published SCED research is largely in accordance with contemporary criteria for experimental quality. Analytic method emerged as an area of discord. Comparison of the findings of this review with historical estimates of the use of statistical analysis indicates an upward trend, but visual analysis remains the most common analytic method and also garners the most support amongst those entities providing SCED standards. Although consensus exists along key dimensions of single-case research design and researchers appear to be practicing within these parameters, there remains a need for further evaluation of assessment and sampling techniques and data analytic methods. PMID:22845874

  11. Peer Management Interventions: A Meta-Analytic Review of Single-Case Research

    Science.gov (United States)

    Dart, Evan H.; Collins, Tai A.; Klingbeil, David A.; McKinley, Lauren E.

    2014-01-01

    Peer management intervention is a subtype of peer-mediated intervention that involves training individuals to implement standardized intervention protocols to modify the behavior of their peers. This meta-analysis of single-case research synthesized the results of 29 studies examining the effectiveness of school-based peer management…

  12. Applying Quality Indicators to Single-Case Research Designs Used in Special Education: A Systematic Review

    Science.gov (United States)

    Moeller, Jeremy D.; Dattilo, John; Rusch, Frank

    2015-01-01

    This study examined how specific guidelines and heuristics have been used to identify methodological rigor associated with single-case research designs based on quality indicators developed by Horner et al. Specifically, this article describes how literature reviews have applied Horner et al.'s quality indicators and evidence-based criteria.…

  13. Academic Benefits of Peer Tutoring: A Meta-Analytic Review of Single-Case Research

    Science.gov (United States)

    Bowman-Perrott, Lisa; Davis, Heather; Vannest, Kimberly; Williams, Lauren; Greenwood, Charles; Parker, Richard

    2013-01-01

    Peer tutoring is an instructional strategy that involves students helping each other learn content through repetition of key concepts. This meta-analysis examined effects of peer tutoring across 26 single-case research experiments for 938 students in Grades 1-12. The TauU effect size for 195 phase contrasts was 0.75 with a confidence interval of…

  14. No Randomization? No Problem: Experimental Control and Random Assignment in Single Case Research

    Science.gov (United States)

    Ledford, Jennifer R.

    2018-01-01

    Randomization of large number of participants to different treatment groups is often not a feasible or preferable way to answer questions of immediate interest to professional practice. Single case designs (SCDs) are a class of research designs that are experimental in nature but require only a few participants, all of whom receive the…

  15. Results of single borehole hydraulic testing in the Mizunami Underground Research Laboratory project. Phase 2

    International Nuclear Information System (INIS)

    Daimaru, Shuji; Takeuchi, Ryuji; Onoe, Hironori; Saegusa, Hiromitsu

    2012-09-01

    This report summarize the results of the single borehole hydraulic tests of 79 sections conducted as part of the Construction phase (Phase 2) in the Mizunami Underground Research Laboratory (MIU) Project. The details of each test (test interval depth, geology, etc.) as well as the interpreted hydraulic parameters and analytical method used are presented in this report. (author)

  16. SINGLE MOLECULE APPROACHES TO BIOLOGY, 2010 GORDON RESEARCH CONFERENCE, JUNE 27-JULY 2, 2010, ITALY

    Energy Technology Data Exchange (ETDEWEB)

    Professor William Moerner

    2010-07-09

    The 2010 Gordon Conference on Single-Molecule Approaches to Biology focuses on cutting-edge research in single-molecule science. Tremendous technical developments have made it possible to detect, identify, track, and manipulate single biomolecules in an ambient environment or even in a live cell. Single-molecule approaches have changed the way many biological problems are addressed, and new knowledge derived from these approaches continues to emerge. The ability of single-molecule approaches to avoid ensemble averaging and to capture transient intermediates and heterogeneous behavior renders them particularly powerful in elucidating mechanisms of biomolecular machines: what they do, how they work individually, how they work together, and finally, how they work inside live cells. The burgeoning use of single-molecule methods to elucidate biological problems is a highly multidisciplinary pursuit, involving both force- and fluorescence-based methods, the most up-to-date advances in microscopy, innovative biological and chemical approaches, and nanotechnology tools. This conference seeks to bring together top experts in molecular and cell biology with innovators in the measurement and manipulation of single molecules, and will provide opportunities for junior scientists and graduate students to present their work in poster format and to exchange ideas with leaders in the field. A number of excellent poster presenters will be selected for short oral talks. Topics as diverse as single-molecule sequencing, DNA/RNA/protein interactions, folding machines, cellular biophysics, synthetic biology and bioengineering, force spectroscopy, new method developments, superresolution imaging in cells, and novel probes for single-molecule imaging will be on the program. Additionally, the collegial atmosphere of this Conference, with programmed discussion sessions as well as opportunities for informal gatherings in the afternoons and evenings in the beauty of the Il Ciocco site in

  17. Enhancing the hermeneutic single-case efficacy design: Bridging the research-practice gap.

    Science.gov (United States)

    Wall, Jessie M; Kwee, Janelle L; Hu, Monica; McDonald, Marvin J

    2017-09-01

    Systematic case study designs are emerging as alternative paradigm strategies for psychotherapy and social science research. Through enhanced sensitivity to context, these designs examine idiographic profiles of causal processes. We specifically advocate the use of the hermeneutic single-case efficacy design (HSCED). HSCED has recently been used to investigate the efficacy of an existing therapy with a new population (Observed and Experiential Integration for athlete performance barriers) and an emerging therapy (Lifespan Integration Therapy). We describe innovations in HSCED that were implemented for these studies. These developments include (a) integrating psychotherapists as case developers, (b) incorporating multiple cases in one investigation, and (c) tailoring the repertoire of assessment tools. These extensions strategically incorporated principles of contextual paradigms in HSCED, thus complementing single-case designs that neglect idiographic contexts. We discuss recommendations for using HSCED in practice-based research, highlighting its potential as a bridge to address the research-practice gap.

  18. Should researchers use single indicators, best indicators, or multiple indicators in structural equation models?

    Directory of Open Access Journals (Sweden)

    Hayduk Leslie A

    2012-10-01

    Full Text Available Abstract Background Structural equation modeling developed as a statistical melding of path analysis and factor analysis that obscured a fundamental tension between a factor preference for multiple indicators and path modeling’s openness to fewer indicators. Discussion Multiple indicators hamper theory by unnecessarily restricting the number of modeled latents. Using the few best indicators – possibly even the single best indicator of each latent – encourages development of theoretically sophisticated models. Additional latent variables permit stronger statistical control of potential confounders, and encourage detailed investigation of mediating causal mechanisms. Summary We recommend the use of the few best indicators. One or two indicators are often sufficient, but three indicators may occasionally be helpful. More than three indicators are rarely warranted because additional redundant indicators provide less research benefit than single indicators of additional latent variables. Scales created from multiple indicators can introduce additional problems, and are prone to being less desirable than either single or multiple indicators.

  19. Fulfilling the law of a single independent variable and improving the result of mathematical educational research

    Science.gov (United States)

    Pardimin, H.; Arcana, N.

    2018-01-01

    Many types of research in the field of mathematics education apply the Quasi-Experimental method and statistical analysis use t-test. Quasi-experiment has a weakness that is difficult to fulfil “the law of a single independent variable”. T-test also has a weakness that is a generalization of the conclusions obtained is less powerful. This research aimed to find ways to reduce the weaknesses of the Quasi-experimental method and improved the generalization of the research results. The method applied in the research was a non-interactive qualitative method, and the type was concept analysis. Concepts analysed are the concept of statistics, research methods of education, and research reports. The result represented a way to overcome the weaknesses of quasi-Experiments and T-test. In addition, the way was to apply a combination of Factorial Design and Balanced Design, which the authors refer to as Factorial-Balanced Design. The advantages of this design are: (1) almost fulfilling “the low of single independent variable” so no need to test the similarity of the academic ability, (2) the sample size of the experimental group and the control group became larger and equal; so it becomes robust to deal with violations of the assumptions of the ANOVA test.

  20. 2012 Gordon Research Conference, Single molecule approaches to biology, July 15-20 2012

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez, Julio M. [Columbia Univ., New York, NY (United States)

    2012-04-20

    Single molecule techniques are rapidly occupying a central role in biological research at all levels. This transition was made possible by the availability and dissemination of robust techniques that use fluorescence and force probes to track the conformation of molecules one at a time, in vitro as well as in live cells. Single-molecule approaches have changed the way many biological problems are studied. These novel techniques provide previously unobtainable data on fundamental biochemical processes that are essential for all forms of life. The ability of single-molecule approaches to avoid ensemble averaging and to capture transient intermediates and heterogeneous behavior renders them particularly powerful in elucidating mechanisms of the molecular systems that underpin the functioning of living cells. Hence, our conference seeks to disseminate the implementation and use of single molecule techniques in the pursuit of new biological knowledge. Topics covered include: Molecular Motors on the Move; Origin And Fate Of Proteins; Physical Principles Of Life; Molecules and Super-resolution Microscopy; Nanoswitches In Action; Active Motion Or Random Diffusion?; Building Blocks Of Living Cells; From Molecular Mechanics To Physiology; Tug-of-war: Force Spectroscopy Of Single Proteins.

  1. Research

    African Journals Online (AJOL)

    In-depth telephonic interviews were voice recorded and transcribed. Through an inductive ... Two research assistants conducted the research to ..... Assistant Nutritionist. 1.25. M. 30.5. Single. BSc Food Science and Technology. Dietitian. 6. M. 25.6. Single. BSc Human Nutrition and Dietetics. Dietitian. 1. M. 29.6. Single.

  2. Air pollution control system research: An iterative approach to developing affordable systems

    Science.gov (United States)

    Watt, Lewis C.; Cannon, Fred S.; Heinsohn, Robert J.; Spaeder, Timothy A.

    1995-01-01

    This paper describes a Strategic Environmental Research and Development Program (SERDP) funded project led jointly by the Marine Corps Multi-Commodity Maintenance Centers, and the Air and Energy Engineering Research Laboratory (AEERL) of the USEPA. The research focuses on paint booth exhaust minimization using recirculation, and on volatile organic compound (VOC) oxidation by the modules of a hybrid air pollution control system. The research team is applying bench, pilot and full scale systems to accomplish the goals of reduced cost and improved effectiveness of air treatment systems for paint booth exhaust.

  3. DEMONSTRATION OF SPLIT-FLOW VENTILATION AND RECIR CULATION AS FLOW-REDUCTION METHODS IN AN AIR FORCE PAINT SPRAY BOOTH - VOLUME I. MAIN REPORT, APPENDICES A-C

    Science.gov (United States)

    During a series of painting operations in a horizontal-flow paint spray booth at Travis AFB, CA, baseline concentrations of four classes of toxic airborne pollutants were measured at 24 locations across a plane immediately forward of the exhaust filters, in the exhaust duct, and ...

  4. Single Crystal and Large Grain Niobium Research at Michigan State University

    Energy Technology Data Exchange (ETDEWEB)

    Compton, Chris; Aizaz, Ahmad; Baars, Derek; Bieler, Tom; Bierwagen, John; Bricker, Steve; Grimm, Terry; Hartung, Walter; Jiang, Hairong; Johnson, Matt; Popielarski, John; Saxton, Laura; Antoine, Claire; Wagner, Bob; Kneisel, Peter

    2007-09-01

    As Superconducting Radio Frequency (SRF) technology is used in more accelerator designs, research has focused on increasing the efficiency of these accelerators by pushing gradients and investigating cast reduction options. Today, most SRF structures are fabricated from high purity niobium. Over years of research, a material specification has been derived that defines a uniaxial, fine gain structure for SRF cavity fabrication. Most recently a push has been made to investigate the merits of using single or large grain niobium as a possible alternative to fine grain niobium. Michigan State University (MSU), in collaboration with Fermi National Accelerator Laboratory (FNAL) and Thomas Jefferson National Accelerator Facility (JLAB), is researching large grain niobium via cavity fabrication processes end testing, as well as exploring materials science issues associated with recrystallization and heat transfer. Single-cell 1.3 GHz (Beta=0.081) cavities made from both fine end large grain niobium were compared both in terms of fabrication procedures and performance. Two 7-cell cavities are currently being fabricated.

  5. Implementation of a single sign-on system between practice, research and learning systems.

    Science.gov (United States)

    Purkayastha, Saptarshi; Gichoya, Judy W; Addepally, Siva Abhishek

    2017-03-29

    Multiple specialized electronic medical systems are utilized in the health enterprise. Each of these systems has their own user management, authentication and authorization process, which makes it a complex web for navigation and use without a coherent process workflow. Users often have to remember multiple passwords, login/logout between systems that disrupt their clinical workflow. Challenges exist in managing permissions for various cadres of health care providers. This case report describes our experience of implementing a single sign-on system, used between an electronic medical records system and a learning management system at a large academic institution with an informatics department responsible for student education and a medical school affiliated with a hospital system caring for patients and conducting research. At our institution, we use OpenMRS for research registry tracking of interventional radiology patients as well as to provide access to medical records to students studying health informatics. To provide authentication across different users of the system with different permissions, we developed a Central Authentication Service (CAS) module for OpenMRS, released under the Mozilla Public License and deployed it for single sign-on across the academic enterprise. The module has been in implementation since August 2015 to present, and we assessed usability of the registry and education system before and after implementation of the CAS module. 54 students and 3 researchers were interviewed. The module authenticates users with appropriate privileges in the medical records system, providing secure access with minimal disruption to their workflow. No passwords requests were sent and users reported ease of use, with streamlined workflow. The project demonstrates that enterprise-wide single sign-on systems should be used in healthcare to reduce complexity like "password hell", improve usability and user navigation. We plan to extend this to work with other

  6. Social validity in single-case research: A systematic literature review of prevalence and application.

    Science.gov (United States)

    Snodgrass, Melinda R; Chung, Moon Y; Meadan, Hedda; Halle, James W

    2018-03-01

    Single-case research (SCR) has been a valuable methodology in special education research. Montrose Wolf (1978), an early pioneer in single-case methodology, coined the term "social validity" to refer to the social importance of the goals selected, the acceptability of procedures employed, and the effectiveness of the outcomes produced in applied investigations. Since 1978, many contributors to SCR have included social validity as a feature of their articles and several authors have examined the prevalence and role of social validity in SCR. We systematically reviewed all SCR published in six highly-ranked special education journals from 2005 to 2016 to establish the prevalence of social validity assessments and to evaluate their scientific rigor. We found relatively low, but stable prevalence with only 28 publications addressing all three factors of the social validity construct (i.e., goals, procedures, outcomes). We conducted an in-depth analysis of the scientific rigor of these 28 publications. Social validity remains an understudied construct in SCR, and the scientific rigor of social validity assessments is often lacking. Implications and future directions are discussed. Copyright © 2018 Elsevier Ltd. All rights reserved.

  7. Meta-Analysis of Single-Case Research Design Studies on Instructional Pacing.

    Science.gov (United States)

    Tincani, Matt; De Mers, Marilyn

    2016-11-01

    More than four decades of research on instructional pacing has yielded varying and, in some cases, conflicting findings. The purpose of this meta-analysis was to synthesize single-case research design (SCRD) studies on instructional pacing to determine the relative benefits of brisker or slower pacing. Participants were children and youth with and without disabilities in educational settings, excluding higher education. Tau-U, a non-parametric statistic for analyzing data in SCRD studies, was used to determine effect size estimates. The article extraction yielded 13 instructional pacing studies meeting contemporary standards for high quality SCRD research. Eleven of the 13 studies reported small to large magnitude effects when two or more pacing parameters were compared, suggesting that instructional pacing is a robust instructional variable. Brisker instructional pacing with brief inter-trial interval (ITI) produced small increases in correct responding and medium to large reductions in challenging behavior compared with extended ITI. Slower instructional pacing with extended wait-time produced small increases in correct responding, but also produced small increases in challenging behavior compared with brief wait-time. Neither brief ITI nor extended wait-time meets recently established thresholds for evidence-based practice, highlighting the need for further instructional pacing research. © The Author(s) 2016.

  8. The Potential Impact of Social Science Research on Legal Issues Surrounding Single-Sex Classrooms and Schools

    Science.gov (United States)

    Eckes, Suzanne Elizabeth; McCall, Stephanie D.

    2014-01-01

    Purpose: This article examines the role social science has played in litigation involving public single-sex educational programs. It also explores a body of social science research related to gender and education that we believe could assist the courts and school leaders in better examining the possibilities and the limitations of single-sex…

  9. Computational fluid dynamics simulation of a single cylinder research engine working with biodiesel

    Directory of Open Access Journals (Sweden)

    Moldovanu Dan

    2013-01-01

    Full Text Available The main objective of the paper is to present the results of the CFD simulation of a DI single cylinder engine using diesel, biodiesel, or different mixture proportions of diesel and biodiesel and compare the results to a test bed measurement in the same functioning point. The engine used for verifying the results of the simulation is a single cylinder research engine from AVL with an open ECU, so that the injection timings and quantities can be controlled and analyzed. In Romania, until the year 2020 all the fuel stations are obliged to have mixtures of at least 10% biodiesel in diesel [14]. The main advantages using mixtures of biofuels in diesel are: the fact that biodiesel is not harmful to the environment; in order to use biodiesel in your engine no modifications are required; the price of biodiesel is smaller than diesel and also if we compare biodiesel production to the classic petroleum based diesel production, it is more energy efficient; biodiesel assures more lubrication to the engine so the life of the engine is increased; biodiesel is a sustainable fuel; using biodiesel helps maintain the environment and it keeps the people more healthy [1-3].

  10. Mass Spectrometry of Single Particles Levitated in an Electrodynamic Balance: Applications to Laboratory Atmospheric Chemistry Research

    Science.gov (United States)

    Birdsall, A.; Krieger, U. K.; Keutsch, F. N.

    2017-12-01

    Dynamic changes to atmospheric aerosol particle composition (e.g., originating from evaporation/condensation, oxidative aging, or aqueous-phase chemical reactions) impact particle properties with importance for understanding particle effects on climate and human health. These changes can take place over the entire lifetime of an atmospheric particle, which can extend over multiple days. Previous laboratory studies of such processes have included analyzing single particles suspended in a levitation device, such as an electrodynamic balance (EDB), an optical levitator, or an acoustic trap, using optical detection techniques. However, studying chemically complex systems can require an analytical method, such as mass spectrometry, that provides more molecular specificity. Existing work coupling particle levitation with mass spectrometry is more limited and largely has consisted of acoustic levitation of millimeter-sized droplets.In this work an EDB has been coupled with a custom-built ionization source and commercial time-of-flight mass spectrometer (MS) as a platform for laboratory atmospheric chemistry research. Single charged particles (radius 10 μm) have been injected into an EDB, levitated for an arbitrarily long period of time, and then transferred to a vaporization-corona discharge ionization region for MS analysis. By analyzing a series of particles of identical composition, residing in the controlled environment of the EDB for varying times, we can trace the chemical evolution of a particle over hours or days, appropriate timescales for understanding transformations of atmospheric particles.To prove the concept of our EDB-MS system, we have studied the evaporation of particles consisting of polyethylene glycol (PEG) molecules of mixed chain lengths, used as a benchmark system. Our system can quantify the composition of single particles (see Figure for sample spectrum of a single PEG-200 particle: PEG parent ions labeled with m/z, known PEG fragment ions

  11. Stability of infants' preference for prosocial others: Implications for research based on single-choice paradigms.

    Science.gov (United States)

    Nighbor, Tyler; Kohn, Carolynn; Normand, Matthew; Schlinger, Henry

    2017-01-01

    Some research suggests infants display a tendency to judge others' prosocial behavior, and in particular, that infants show a strong preference for prosocial others. For example, data from one frequently cited and well-publicized study showed that, after watching a puppet show with three puppets, 74% of infants chose the puppet that "helped" rather than the puppet that "hindered" a third puppet from attaining its goal. The purpose of the current investigation was to replicate these methods and extend them by including a within-subject measure of infant puppet choice across repeated trials to assess the stability of infants' choice. In the current study, 20 infants viewed a puppet show and chose between two puppets (i.e., helper or hinderer) immediately following the puppet show. Although results were similar to previously published work on the first-choice trial (65% of infants chose the helper puppet on the first trial), infants did not consistently choose the helper across trials; several infants demonstrated a side preference, with 9 infants almost exclusively choosing puppets presented on the right or left side. The current investigation addressed limitations of previous research by including a between-subjects (replication) as well as a within-subjects (extension) repeated measure of choice that allowed for the examination of the stability of the choice measure. Our results, particularly in light of other failed replications, raise questions regarding the robustness of infants' preference for prosocial others and the reliability and validity of the single-choice paradigm.

  12. Single Case Method in Psychology: How to Improve as a Possible Methodology in Quantitative Research.

    Science.gov (United States)

    Krause-Kjær, Elisa; Nedergaard, Jensine I

    2015-09-01

    Awareness of including Single-Case Method (SCM), as a possible methodology in quantitative research in the field of psychology, has been argued as useful, e.g., by Hurtado-Parrado and López-López (IPBS: Integrative Psychological & Behavioral Science, 49:2, 2015). Their article introduces a historical and conceptual analysis of SCMs and proposes changing the, often prevailing, tendency of neglecting SCM as an alternative to Null Hypothesis Significance Testing (NHST). This article contributes by putting a new light on SCM as an equally important methodology in psychology. The intention of the present article is to elaborate this point of view further by discussing one of the most fundamental requirements as well as main characteristics of SCM regarding temporality. In this respect that; "…performance is assessed continuously over time and under different conditions…" Hurtado-Parrado and López-López (IPBS: Integrative Psychological & Behavioral Science, 49:2, 2015). Defining principles when it comes to particular units of analysis, both synchronic (spatial) and diachronic (temporal) elements should be incorporated. In this article misunderstandings of the SCM will be adduced, and further the temporality will be described in order to propose how the SCM could have a more severe usability in psychological research. It is further discussed how to implement SCM in psychological methodology. It is suggested that one solution might be to reconsider the notion of time in psychological research to cover more than a variable of control and in this respect also include the notion of time as an irreversible unity within life.

  13. FIREX-Related Biomass Burning Research Using ARM Single-Particle Soot Photometer Field Campaign Report

    Energy Technology Data Exchange (ETDEWEB)

    Onasch, Timothy B [Aerodyne Research, Inc.; Sedlacek, Arthur J [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2017-03-15

    The scientific focus of this study was to investigate and quantify the mass loadings, chemical compositions, and optical properties of biomass burning particulate emissions generated in the laboratory from Western U.S. fuels using a similar instrument suite to the one deployed on the U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility Gulfstream-1 (G-1) aircraft during the 2013 Biomass Burning Observation Project (BBOP) field study (Kleinman and Sedlacek, 2013). We deployed the single-particle soot photometer (SP2) to make measurements of biomass burning refractory black carbon (rBC) mass loadings and size distributions to correlate with non-refractory particulate matter (NR-PM; i.e., HR-AMS) and rBC (SP-AMS) measurements as a function of photo-oxidation processes in an environmental chamber. With these measurements, we will address the following scientific questions: 1. What are the emission indices (g/kg fuel) of rBC from various wildland fuels from the Pacific Northwest (i.e., relevant to BBOP analysis) as a function of combustion conditions and simulated atmospheric processing in an environmental chamber? 2. What are the optical properties (e.g., mass-specific absorption cross-section [MAC], single-scattering albedo [SSA], and absorption Angstrom exponent [AAE)] of rBC emitted from various wildland fuels and how are they impacted by atmospheric processing? 3. How does the mixing state of rBC in biomass-burning plumes relate to the optical properties? 4. How does the emitted rBC affect radiative forcing?

  14. An Aggregate Study of Single-Case Research Involving Aided AAC: Participant Characteristics of Individuals with Autism Spectrum Disorders

    Science.gov (United States)

    Ganz, Jennifer B.; Earles-Vollrath, Theresa L.; Mason, Rose A.; Rispoli, Mandy J.; Heath, Amy K.; Parker, Richard I.

    2011-01-01

    Individuals with autism spectrum disorders (ASD) who cannot speak at all or not intelligibly are frequently taught to use aided augmentative and alternative communication (AAC). The majority of the research on the use of AAC with individuals with ASD has been single-case research studies. This investigation involved a meta-analysis of the…

  15. Green systems biology - From single genomes, proteomes and metabolomes to ecosystems research and biotechnology.

    Science.gov (United States)

    Weckwerth, Wolfram

    2011-12-10

    Plants have shaped our human life form from the outset. With the emerging recognition of world population feeding, global climate change and limited energy resources with fossil fuels, the relevance of plant biology and biotechnology is becoming dramatically important. One key issue is to improve plant productivity and abiotic/biotic stress resistance in agriculture due to restricted land area and increasing environmental pressures. Another aspect is the development of CO(2)-neutral plant resources for fiber/biomass and biofuels: a transition from first generation plants like sugar cane, maize and other important nutritional crops to second and third generation energy crops such as Miscanthus and trees for lignocellulose and algae for biomass and feed, hydrogen and lipid production. At the same time we have to conserve and protect natural diversity and species richness as a foundation of our life on earth. Here, biodiversity banks are discussed as a foundation of current and future plant breeding research. Consequently, it can be anticipated that plant biology and ecology will have more indispensable future roles in all socio-economic aspects of our life than ever before. We therefore need an in-depth understanding of the physiology of single plant species for practical applications as well as the translation of this knowledge into complex natural as well as anthropogenic ecosystems. Latest developments in biological and bioanalytical research will lead into a paradigm shift towards trying to understand organisms at a systems level and in their ecosystemic context: (i) shotgun and next-generation genome sequencing, gene reconstruction and annotation, (ii) genome-scale molecular analysis using OMICS technologies and (iii) computer-assisted analysis, modeling and interpretation of biological data. Systems biology combines these molecular data, genetic evolution, environmental cues and species interaction with the understanding, modeling and prediction of active

  16. Stability of infants’ preference for prosocial others: Implications for research based on single-choice paradigms

    Science.gov (United States)

    Normand, Matthew; Schlinger, Henry

    2017-01-01

    Some research suggests infants display a tendency to judge others’ prosocial behavior, and in particular, that infants show a strong preference for prosocial others. For example, data from one frequently cited and well-publicized study showed that, after watching a puppet show with three puppets, 74% of infants chose the puppet that “helped” rather than the puppet that “hindered” a third puppet from attaining its goal. The purpose of the current investigation was to replicate these methods and extend them by including a within-subject measure of infant puppet choice across repeated trials to assess the stability of infants’ choice. In the current study, 20 infants viewed a puppet show and chose between two puppets (i.e., helper or hinderer) immediately following the puppet show. Although results were similar to previously published work on the first-choice trial (65% of infants chose the helper puppet on the first trial), infants did not consistently choose the helper across trials; several infants demonstrated a side preference, with 9 infants almost exclusively choosing puppets presented on the right or left side. The current investigation addressed limitations of previous research by including a between-subjects (replication) as well as a within-subjects (extension) repeated measure of choice that allowed for the examination of the stability of the choice measure. Our results, particularly in light of other failed replications, raise questions regarding the robustness of infants’ preference for prosocial others and the reliability and validity of the single-choice paradigm. PMID:28575051

  17. Single-Case Research Methods: History and Suitability for a Psychological Science in Need of Alternatives.

    Science.gov (United States)

    Hurtado-Parrado, Camilo; López-López, Wilson

    2015-09-01

    This paper presents a historical and conceptual analysis of a group of research strategies known as the Single-Case Methods (SCMs). First, we present an overview of the SCMs, their history, and their major proponents. We will argue that the philosophical roots of SCMs can be found in the ideas of authors who recognized the importance of understanding both the generality and individuality of psychological functioning. Second, we will discuss the influence that the natural sciences' attitude toward measurement and experimentation has had on SCMs. Although this influence can be traced back to the early days of experimental psychology, during which incipient forms of SCMs appeared, SCMs reached full development during the subsequent advent of Behavior Analysis (BA). Third, we will show that despite the success of SCMs in BA and other (mainly applied) disciplines, these designs are currently not prominent in psychology. More importantly, they have been neglected as a possible alternative to one of the mainstream approaches in psychology, the Null Hypothesis Significance Testing (NHST), despite serious controversies about the limitations of this prevailing method. Our thesis throughout this section will be that SCMs should be considered as an alternative to NHST because many of the recommendations for improving the use of significance testing (Wilkinson & the TFSI, 1999) are main characteristics of SCMs. The paper finishes with a discussion of a number of the possible reasons why SCMs have been neglected.

  18. Research report 24 single-family dwellings from the fifties; Onderzoekrapport 24 eengezinswoningen jaren '50

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-05-15

    This analysis is part of a coordinated series of studies for different residential building complexes of different corporations. This research report concerns the quick scan to decide on investments for the improvement of three single-family houses complexes, which were built in 1959. Based on four financial scenarios a framework is set up by means of which an integrated investment assessment can be made. In the study, scores are given for improving energy efficiency, reducing emission, quality of the construction, technical quality, urban and architectural quality, indoor environment, social aspects, etc. [Dutch] Deze analyse is onderdeel van een gecoordineerde serie onderzoeken voor verschillende complexen van verschillende corporaties. Dit onderzoeksrapport betreft de quickscan voor de investeringsafweging voor de verbetering van een drietal complexen van het type eengezinswoningen eind jaren vijftig. Op basis van vier financieel onderbouwde scenario's wordt het kader geschetst waarmee een integrale investeringsafweging kan worden gemaakt. In het onderzoek worden waarderingen gegeven voor de verbetering van de aspecten energiezuinigheid, uitstoot), bouwtechnisch kwaliteit, markttechnische kwaliteit, stedenbouwkundige en architectonische kwaliteit, binnenklimaat, sociale aspecten, etc.

  19. Research of Medical Expenditure among Inpatients with Unstable Angina Pectoris in a Single Center.

    Science.gov (United States)

    Wu, Suo-Wei; Pan, Qi; Chen, Tong; Wei, Liang-Yu; Xuan, Yong; Wang, Qin; Li, Chao; Song, Jing-Chen

    2017-07-05

    With the rising incidence as well as the medical expenditure among patients with unstable angina pectoris, the research aimed to investigate the inpatient medical expenditure through the combination of diagnosis-related groups (DRGs) among patients with unstable angina pectoris in a Grade A tertiary hospital to conduct the referential standards of medical costs for the diagnosis. Single-factor analysis and multiple linear stepwise regression method were used to investigate 3933 cases between 2014 and 2016 in Beijing Hospital (China) whose main diagnosis was defined as unstable angina pectoris to determine the main factors influencing the inpatient medical expenditure, and decision tree method was adopted to establish the model of DRGs grouping combinations. The major influential factors of inpatient medical expenditure included age, operative method, therapeutic effects as well as comorbidity and complications (CCs) of the disease, and the 3933 cases were divided into ten DRGs by four factors: age, CCs, therapeutic effects, and the type of surgery with corresponding inpatient medical expenditure standards setup. Data of nonparametric test on medical costs among different groups were all significant (P unstable angina pectoris is conducive in standardizing the diagnosis and treatment behaviors of the hospital and reducing economic burdens among patients.

  20. Experimental research on the stability of armour and secondary layer in a single layered Tetrapod breakwater

    NARCIS (Netherlands)

    De Jong, W.; Verhagen, H.J.; Olthof, J.

    2004-01-01

    Physical model tests were done on an armour of Tetrapods, placed in a single layer. The objective of the investigations was to study the stability of the secondary layer, and to see if the material of this secondary layer could be washed out through the single layer of Tetrapods. It was concluded

  1. Results of single borehole hydraulic tests in the Mizunami Underground Research Laboratory project. FY 2012 - FY 2015

    International Nuclear Information System (INIS)

    Onoe, Hironori; Takeuchi, Ryuji

    2016-11-01

    This report summarize the results of the single borehole hydraulic tests of 151 sections carried out at the -300 m Stage and the -500 m Stage of the Mizunami Underground Research Laboratory from FY 2012 to FY 2015. The details of each test (test interval depth, geology, etc.) as well as the interpreted hydraulic parameters and analytical methods used are presented in this report. Furthermore, the previous results of the single borehole hydraulic tests carried out in the Regional Hydrogeological Study Project and the Mizunami Underground Research Laboratory Project before FY 2012 are also summarized in this report. (author)

  2. Biomass Burning Research Using DOE ARM Single-Particle Soot Photometer (SP2) Field Campaign Report

    Energy Technology Data Exchange (ETDEWEB)

    Onasch, Timothy B [Aerodyne Research, Inc., Billerica, MA (United States); Sedlacek, Arthur J [Brookhaven National Lab. (BNL), Upton, NY (United States); Lewis, Ernie [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2017-03-01

    The focus of this laboratory study was to investigate the chemical and optical properties, and the detection efficiencies, of tar balls generated in the laboratory using the same instruments deployed on the U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility Gulfstream-1 (G-1) aircraft during the 2013 Biomass Burning Observation Project (BBOP) field study, during which tar balls were observed in wildland biomass burning particulate emissions. Key goals of this laboratory study were: (a) measuring the chemical composition of tar balls to provide insights into the atmospheric processes that form (evaporation/oxidation) and modify them in biomass burning plumes, (b) identifying whether tar balls contain refractory black carbon, (c) determining the collection efficiencies of tar balls impacting on the 600oC heated tungsten vaporizer in the Aerodyne Soot Particle Aerosol Mass Spectrometer (SP-AMS) (i.e., given the observed low volatilities, AMS measurements might underestimate organic biomass burning plume loadings), and (d) measuring the wavelength-dependent, mass-specific absorption cross-sections of brown carbon components of tar balls. This project was funded primarily by the DOE Atmospheric System Research (ASR) program, and the ARM Facility made their single-particle soot photometer (SP2) available for September 1-September 31, 2016 in the Aerodyne laboratories. The ARM mentor (Dr. Sedlacek) requested no funds for mentorship or data reduction. All ARM SP2 data collected as part of this project are archived in the ARM Data Archive in accordance with established protocols. The main objectives of the ARM Biomass Burning Observation Period (BBOP, July-October, 2013) field campaign were to (1) assess the impact of wildland fires in the Pacific Northwest on climate, through near-field and regional intensive measurement campaigns, and (2) investigate agricultural burns to determine how those biomass burn plumes differ from

  3. Meta-Analysis of Single-Case Design Research on Self-Regulatory Interventions for Academic Performance

    Science.gov (United States)

    Perry, Valerie; Albeg, Loren; Tung, Catherine

    2012-01-01

    The current study examined the effects of self-regulatory interventions on reading, writing, and math by conducting a meta-analysis of single-case design research. Self-regulatory interventions have promise as an effective approach that is both minimally invasive and involves minimal resources. Effects of the interventions were analyzed by…

  4. Promoting Positive Behavior Using the Good Behavior Game: A Meta-Analysis of Single-Case Research

    Science.gov (United States)

    Bowman-Perrott, Lisa; Burke, Mack D.; Zaini, Samar; Zhang, Nan; Vannest, Kimberly

    2016-01-01

    The Good Behavior Game (GBG) is a classroom management strategy that uses an interdependent group-oriented contingency to promote prosocial behavior and decrease problem behavior. This meta-analysis synthesized single-case research (SCR) on the GBG across 21 studies, representing 1,580 students in pre-kindergarten through Grade 12. The TauU effect…

  5. Self-Management Interventions on Students with Autism: A Meta-Analysis of Single-Subject Research

    Science.gov (United States)

    Carr, Monica E.; Moore, Dennis W.; Anderson, Angelika

    2014-01-01

    Self-management interventions aimed at skill acquisition and/or improving behavior of students diagnosed with autism spectrum disorders were examined. Twenty-three single-subject research design studies met inclusion criteria. Quality assessment of these studies was conducted using the What Works Clearinghouse guidelines, and treatment effect…

  6. Caught between a rock and a hard place: An intrinsic single case study of nurse researchers' experiences of the presence of a nursing research culture in clinical practice.

    Science.gov (United States)

    Berthelsen, Connie Bøttcher; Hølge-Hazelton, Bibi

    2018-04-01

    To explore how nurse researchers in clinical positions experience the presence of a nursing research culture in clinical practice. Higher demands in the hospitals for increasing the quality of patient care engender a higher demand for the skills of health professionals and evidence-based practice. However, the utilisation of nursing research in clinical practice is still limited. Intrinsic single case study design underlined by a constructivist perspective. Data were produced through a focus group interview with seven nurse researchers employed in clinical practice in two university hospitals in Zealand, Denmark, to capture the intrinsic aspects of the concept of nursing research culture in the context of clinical practice. A thematic analysis was conducted based on Braun and Clarke's theoretical guideline. "Caught between a rock and a hard place" was constructed as the main theme describing how nurse researchers in clinical positions experience the presence of a nursing research culture in clinical practice. The main theme was supported by three subthemes: Minimal academic tradition affects nursing research; Minimal recognition from physicians affects nursing research; and Moving towards a research culture. The nurse researchers in this study did not experience the presence of a nursing research culture in clinical practice, however; they called for more attention on removing barriers against research utilisation, promotion of applied research and interdisciplinary research collaboration, and passionate management support. The results of this case study show the pressure which nurse researchers employed in clinical practice are exposed to, and give examples on how to accommodate the further development of a nursing research culture in clinical practice. © 2017 John Wiley & Sons Ltd.

  7. Research Update: Molecular electronics: The single-molecule switch and transistor

    Directory of Open Access Journals (Sweden)

    Kai Sotthewes

    2014-01-01

    Full Text Available In order to design and realize single-molecule devices it is essential to have a good understanding of the properties of an individual molecule. For electronic applications, the most important property of a molecule is its conductance. Here we show how a single octanethiol molecule can be connected to macroscopic leads and how the transport properties of the molecule can be measured. Based on this knowledge we have realized two single-molecule devices: a molecular switch and a molecular transistor. The switch can be opened and closed at will by carefully adjusting the separation between the electrical contacts and the voltage drop across the contacts. This single-molecular switch operates in a broad temperature range from cryogenic temperatures all the way up to room temperature. Via mechanical gating, i.e., compressing or stretching of the octanethiol molecule, by varying the contact's interspace, we are able to systematically adjust the conductance of the electrode-octanethiol-electrode junction. This two-terminal single-molecule transistor is very robust, but the amplification factor is rather limited.

  8. Mobile clusters of single board computers: an option for providing resources to student projects and researchers.

    Science.gov (United States)

    Baun, Christian

    2016-01-01

    Clusters usually consist of servers, workstations or personal computers as nodes. But especially for academic purposes like student projects or scientific projects, the cost for purchase and operation can be a challenge. Single board computers cannot compete with the performance or energy-efficiency of higher-value systems, but they are an option to build inexpensive cluster systems. Because of the compact design and modest energy consumption, it is possible to build clusters of single board computers in a way that they are mobile and can be easily transported by the users. This paper describes the construction of such a cluster, useful applications and the performance of the single nodes. Furthermore, the clusters' performance and energy-efficiency is analyzed by executing the High Performance Linpack benchmark with a different number of nodes and different proportion of the systems total main memory utilized.

  9. Meta-Analysis of Behavioral Self-Management Interventions in Single-Case Research

    Science.gov (United States)

    Briesch, Amy M.; Briesch, Jacquelyn M.

    2016-01-01

    The current study meta-analyzed 47 single-subject studies of behavioral self-management interventions that were published between 1971 and 2011. In addition to obtaining an overall measure of effect across all self-management studies (f = 0.93), analyses were conducted to assess whether treatment effectiveness was moderated by factors such as…

  10. Finding Order in Randomness: Single-Molecule Studies Reveal Stochastic RNA Processing | Center for Cancer Research

    Science.gov (United States)

    Producing a functional eukaryotic messenger RNA (mRNA) requires the coordinated activity of several large protein complexes to initiate transcription, elongate nascent transcripts, splice together exons, and cleave and polyadenylate the 3’ end. Kinetic competition between these various processes has been proposed to regulate mRNA maturation, but this model could lead to multiple, randomly determined, or stochastic, pathways or outcomes. Regulatory checkpoints have been suggested as a means of ensuring quality control. However, current methods have been unable to tease apart the contributions of these processes at a single gene or on a time scale that could provide mechanistic insight. To begin to investigate the kinetic relationship between transcription and splicing, Daniel Larson, Ph.D., of CCR’s Laboratory of Receptor Biology and Gene Expression, and his colleagues employed a single-molecule RNA imaging approach to monitor production and processing of a human β-globin reporter gene in living cells.

  11. A research on the positioning technology of vehicle navigation system from single source to "ASPN"

    Science.gov (United States)

    Zhang, Jing; Li, Haizhou; Chen, Yu; Chen, Hongyue; Sun, Qian

    2017-10-01

    Due to the suddenness and complexity of modern warfare, land-based weapon systems need to have precision strike capability on roads and railways. The vehicle navigation system is one of the most important equipments for the land-based weapon systems that have precision strick capability. There are inherent shortcomings for single source navigation systems to provide continuous and stable navigation information. To overcome the shortcomings, the multi-source positioning technology is developed. The All Source Positioning and Navigaiton (ASPN) program was proposed in 2010, which seeks to enable low cost, robust, and seamless navigation solutions for military to use on any operational platform and in any environment with or without GPS. The development trend of vehicle positioning technology was reviewed in this paper. The trend indicates that the positioning technology is developed from single source and multi-source to ASPN. The data fusion techniques based on multi-source and ASPN was analyzed in detail.

  12. A novel single-cavity three-wavelength photoacoustic spectrometer for atmospheric aerosol research

    Directory of Open Access Journals (Sweden)

    C. Linke

    2016-11-01

    Full Text Available The spectral light-absorbing behavior of carbonaceous aerosols varies depending on the chemical composition and structure of the particles. A new single-cavity three-wavelength photoacoustic spectrometer was developed and characterized for measuring absorption coefficients at three wavelengths across the visible spectral range. In laboratory studies, several types of soot with different organic content were generated by a diffusion flame burner and were investigated for changes in mass-specific absorption cross section (MAC values, absorption and scattering Ångström exponents (αabs and αsca, and single scattering albedo (ω. By increasing the organic carbonaceous (OC content of the aerosol from 50 to 90 % of the total carbonaceous mass, for 660 nm nearly no change of MAC was found with increasing OC content. In contrast, for 532 nm a significant increase, and for 445 nm a strong increase of MAC was found with increasing OC content of the aerosol. Depending on the OC content, the Ångström exponents of absorption and scattering as well as the single scattering albedo increased. These laboratory results were compared to a field study at a traffic-dominated urban site, which was also influenced by residential wood combustion. For this site a daily average value of αabs(445–660 of 1.9 was found.

  13. Single-crystal neutron diffraction at the Australian Replacement Research Reactor

    International Nuclear Information System (INIS)

    Klooster, W.T.

    2001-01-01

    The purpose of the workshop was to: identify the future needs and opportunities for single-crystal neutron diffraction, and specify instrument requirements. important number of experiments. The conclusion of the workshop deliberation was that Australia has a diverse community of users of single-crystal neutron diffraction. A (quasi)-Laue image-plate diffractometer allows the fastest throughput by far, but would exclude an important number of experiments. Most of these could be covered by the additional possibility to locate the image-plate detector on a monochromatic beam. Therefore it was recommend both a white thermal beam and a monochromatic beam (λ= 1 to 2.4 Angstroms) for an image-plate detector. At little additional cost the existing 2TanA instrument could be located semi-permanently on the same monochromatic beam, thus offering three quite different types of single-crystal instruments. Small improvements could be made to the 2TanA instrument to cater for the remaining experiments not suited to an image-plate diffractometer: exchange of the Eulerian cradle for an automated tilt goniometer for extremely bulky sample environment (cryomagnets, large pressure cells), optional larger area detector, analyser crystal. It was recommended that an Instrument Advisory Team will be assembled, and will help in specifying, designing and commissioning the instrument

  14. Implementation research: reactive mass vaccination with single-dose oral cholera vaccine, Zambia.

    Science.gov (United States)

    Poncin, Marc; Zulu, Gideon; Voute, Caroline; Ferreras, Eva; Muleya, Clara Mbwili; Malama, Kennedy; Pezzoli, Lorenzo; Mufunda, Jacob; Robert, Hugues; Uzzeni, Florent; Luquero, Francisco J; Chizema, Elizabeth; Ciglenecki, Iza

    2018-02-01

    To describe the implementation and feasibility of an innovative mass vaccination strategy - based on single-dose oral cholera vaccine - to curb a cholera epidemic in a large urban setting. In April 2016, in the early stages of a cholera outbreak in Lusaka, Zambia, the health ministry collaborated with Médecins Sans Frontières and the World Health Organization in organizing a mass vaccination campaign, based on single-dose oral cholera vaccine. Over a period of 17 days, partners mobilized 1700 health ministry staff and community volunteers for community sensitization, social mobilization and vaccination activities in 10 townships. On each day, doses of vaccine were delivered to vaccination sites and administrative coverage was estimated. Overall, vaccination teams administered 424 100 doses of vaccine to an estimated target population of 578 043, resulting in an estimated administrative coverage of 73.4%. After the campaign, few cholera cases were reported and there was no evidence of the disease spreading within the vaccinated areas. The total cost of the campaign - 2.31 United States dollars (US$) per dose - included the relatively low cost of local delivery - US$ 0.41 per dose. We found that an early and large-scale targeted reactive campaign using a single-dose oral vaccine, organized in response to a cholera epidemic within a large city, to be feasible and appeared effective. While cholera vaccines remain in short supply, the maximization of the number of vaccines in response to a cholera epidemic, by the use of just one dose per member of an at-risk community, should be considered.

  15. Research of documents pertaining to waste migration from leaking single-shell tanks

    Energy Technology Data Exchange (ETDEWEB)

    Consort, S.D. [ICF Kaiser Hanford Co., Richland, WA (United States)

    1994-09-30

    This report contains the results from an investigation of the literature concerning single-shell tank (SST) leaks on the Hanford Site. The purpose of the investigation is to determine if available data confirm or refute the assertion that leaked waste from the SSTs has reached ground water. There are 67 leaking single-shell tanks (SSTs) on the Hanford Site. Although the maximum volume of leaked waste is approximately 4,013,000 L (1,060,000 gal), it is not the only waste in the ground beneath the 200 Area. Before 1966, supernatant solution was intentionally discharged from the cascading SSTs to the ground. Other leaks from piping and surface spills contributed to the waste in the ground. The maximum estimated volume of unintentionally leaked waste from the tanks is less than 1% of the intentionally released liquid waste that was sent to the cribs and trenches from the SSTs. The volume does not include the liquid waste sent intentionally from other facilities directly to the cribs, trenches, and injection wells. The components and concentrations of the intentionally released waste were in compliance with applicable standards at the time of release.

  16. Inclusion of non-English-speaking patients in research: A single institution experience.

    Science.gov (United States)

    Bernier, Rachel; Halpin, Erin; Staffa, Steven J; Benson, Lindsey; DiNardo, James A; Nasr, Viviane G

    2018-03-30

    Considering the recent increase in medical care provided to patients from foreign countries and the diversity of languages spoken by families living within the United States, it is important to determine whether non-English-speaking patients have access to participate in clinical research from which they may benefit. We aimed to determine the number of non-English-speaking patients presenting to Boston Children's Hospital for medical care between 2011 and 2016, the number of clinical research protocols active within the Department of Anesthesiology, Critical Care and Pain Medicine approved to enroll non-English-speaking patients, as well as the number of both non-English- and English-speaking patients approached and enrolled in these studies. Furthermore, we attempted to determine barriers that may have prevented non-English-speaking patients from inclusion in clinical research. We conducted a retrospective review of various data sources during a 5-year period. Data included the number of non-English-speaking patients presenting to Boston Children's Hospital for care as well as the number of English- and non-English-speaking patients approached for studies at the Department of Anesthesiology each year. Additionally, we reviewed data from the IRB which included the justification that research teams provided when opting to exclude non-English-speaking participants. In addition, we attempted to determine the barriers that may have prevented these patients from inclusion in research protocols. We found that the number of non-English-speaking patients presenting to Boston Children's Hospital increased over time. However, the number of studies approved to enroll non-English-speaking patients within the Department of Anesthesiology and the rate of enrollment of these patients did not increase at the same rate. In order to increase the number of non-English-speaking patients approached to participate in research, we must improve cultural awareness and provide investigators

  17. The pipeline project: Pre-publication independent replications of a single laboratory's research pipeline

    NARCIS (Netherlands)

    M. Schweinsberg (Martin); Madan, N. (Nikhil); M. Vianello (Michelangelo); Sommer, S.A. (S. Amy); Jordan, J. (Jennifer); Tierney, W. (Warren); Awtrey, E. (Eli); Zhu, L.L. (Luke Lei); Diermeier, D. (Daniel); Heinze, J.E. (Justin E.); Srinivasan, M. (Malavika); Tannenbaum, D. (David); Bivolaru, E. (Eliza); Dana, J. (Jason); Davis-Stober, C.P. (Clintin P.); C. Du Plessis (Christilene); Gronau, Q.F. (Quentin F.); Hafenbrack, A.C. (Andrew C.); Liao, E.Y. (Eko Yi); Ly, A. (Alexander); Marsman, M. (Maarten); Murase, T. (Toshio); Qureshi, I. (Israr); Schaerer, M. (Michael); Thornley, N. (Nico); Tworek, C.M. (Christina M.); E.J. Wagenmakers (Eric-Jan); Wong, L. (Lynn); Anderson, T. (Tabitha); Bauman, C.W. (Christopher W.); Bedwell, W.L. (Wendy L.); Brescoll, V. (Victoria); Canavan, A. (Andrew); J. Chandler (Jesse); Cheries, E. (Erik); Cheryan, S. (Sapna); Cheung, F. (Felix); Cimpian, A. (Andrei); Clark, M.A. (Mark A.); Cordon, D. (Diana); Cushman, F. (Fiery); Ditto, P.H. (Peter H.); Donahue, T. (Thomas); Frick, S.E. (Sarah E.); Gamez-Djokic, M. (Monica); Grady, R.H. (Rebecca Hofstein); Graham, J. (Jesse); Gu, J. (Jun); Hahn, A. (Adam); Hanson, B.E. (Brittany E.); Hartwich, N.J. (Nicole J.); Hein, K. (Kristie); Inbar, Y. (Yoel); Jiang, L. (Lily); Kellogg, T. (Tehlyr); Kennedy, D.M. (Deanna M.); Legate, N. (Nicole); Luoma, T.P. (Timo P.); Maibuecher, H. (Heidi); Meindl, P. (Peter); Miles, J. (Jennifer); Mislin, A. (Alexandra); Molden, D.C. (Daniel C.); Motyl, M. (Matt); Newman, G. (George); Ngo, H.H. (Hoai Huong); Packham, H. (Harvey); Ramsay, P.S. (Philip S.); Ray, J.L. (Jennifer L.); Sackett, A.M. (Aaron M.); Sellier, A.-L. (Anne-Laure); Sokolova, T. (Tatiana); Sowden, W. (Walter); Storage, D. (Daniel); Sun, X. (Xiaomin); Van Bavel, J.J. (Jay J.); Washburn, A.N. (Anthony N.); Wei, C. (Cong); Wetter, E. (Erik); Wilson, C.T. (Carlos T.); Darroux, S.-C. (Sophie-Charlotte); Uhlmann, E.L. (Eric Luis)

    2016-01-01

    textabstractThis crowdsourced project introduces a collaborative approach to improving the reproducibility of scientific research, in which findings are replicated in qualified independent laboratories before (rather than after) they are published. Our goal is to establish a non-adversarial

  18. Single Group, Pre- and Post-Test Research Designs: Some Methodological Concerns

    Science.gov (United States)

    Marsden, Emma; Torgerson, Carole J.

    2012-01-01

    This article provides two illustrations of some of the factors that can influence findings from pre- and post-test research designs in evaluation studies, including regression to the mean (RTM), maturation, history and test effects. The first illustration involves a re-analysis of data from a study by Marsden (2004), in which pre-test scores are…

  19. Electrodynamic balance-mass spectrometry of single particles as a new platform for atmospheric chemistry research

    Science.gov (United States)

    Birdsall, Adam W.; Krieger, Ulrich K.; Keutsch, Frank N.

    2018-01-01

    New analytical techniques are needed to improve our understanding of the intertwined physical and chemical processes that affect the composition of aerosol particles in the Earth's atmosphere, such as gas-particle partitioning and homogenous or heterogeneous chemistry, and their ultimate relation to air quality and climate. We describe a new laboratory setup that couples an electrodynamic balance (EDB) to a mass spectrometer (MS). The EDB stores a single laboratory-generated particle in an electric field under atmospheric conditions for an arbitrarily long length of time. The particle is then transferred via gas flow to an ionization region that vaporizes and ionizes the analyte molecules before MS measurement. We demonstrate the feasibility of the technique by tracking evaporation of polyethylene glycol molecules and finding agreement with a kinetic model. Fitting data to the kinetic model also allows determination of vapor pressures to within a factor of 2. This EDB-MS system can be used to study fundamental chemical and physical processes involving particles that are difficult to isolate and study with other techniques. The results of such measurements can be used to improve our understanding of atmospheric particles.

  20. Research Techniques Made Simple: Experimental Methodology for Single-Cell Mass Cytometry.

    Science.gov (United States)

    Matos, Tiago R; Liu, Hongye; Ritz, Jerome

    2017-04-01

    Growing recognition of the complexity of interactions within cellular systems has fueled the development of mass cytometry. The precision of time-of-flight mass spectrometry combined with the labeling of specific ligands with mass tags enables detection and quantification of more than 40 markers at a single-cell resolution. The 135 available detection channels allow simultaneous study of additional characteristics of complex biological systems across millions of cells. Cutting-edge mass cytometry by time-of-flight (CyTOF) can profoundly affect our knowledge of cell population heterogeneity and hierarchy, cellular state, multiplexed signaling pathways, proteolysis products, and mRNA transcripts. Although CyTOF is currently scarcely used within the field of investigative dermatology, we aim to highlight CyTOF's utility and demystify the technique. CyTOF may, for example, uncover the immunological heterogeneity and differentiation of Langerhans cells, delineate the signaling pathways responsible for each phase of the hair cycle, or elucidate which proteolysis products from keratinocytes promote skin inflammation. However, the success of mass cytometry experiments depends on fully understanding the methods and how to control for variations when making comparisons between samples. Here, we review key experimental methods for CyTOF that enable accurate data acquisition by optimizing signal detection and minimizing background noise and sample-to-sample variation. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  1. Common single nucleotide variants underlying drug addiction: more than a decade of research.

    Science.gov (United States)

    Bühler, Kora-Mareen; Giné, Elena; Echeverry-Alzate, Victor; Calleja-Conde, Javier; de Fonseca, Fernando Rodriguez; López-Moreno, Jose Antonio

    2015-09-01

    Drug-related phenotypes are common complex and highly heritable traits. In the last few years, candidate gene (CGAS) and genome-wide association studies (GWAS) have identified a huge number of single nucleotide polymorphisms (SNPs) associated with drug use, abuse or dependence, mainly related to alcohol or nicotine. Nevertheless, few of these associations have been replicated in independent studies. The aim of this study was to provide a review of the SNPs that have been most significantly associated with alcohol-, nicotine-, cannabis- and cocaine-related phenotypes in humans between the years of 2000 and 2012. To this end, we selected CGAS, GWAS, family-based association and case-only studies published in peer-reviewed international scientific journals (using the PubMed/MEDLINE and Addiction GWAS Resource databases) in which a significant association was reported. A total of 371 studies fit the search criteria. We then filtered SNPs with at least one replication study and performed meta-analysis of the significance of the associations. SNPs in the alcohol metabolizing genes, in the cholinergic gene cluster CHRNA5-CHRNA3-CHRNB4, and in the DRD2 and ANNK1 genes, are, to date, the most replicated and significant gene variants associated with alcohol- and nicotine-related phenotypes. In the case of cannabis and cocaine, a far fewer number of studies and replications have been reported, indicating either a need for further investigation or that the genetics of cannabis/cocaine addiction are more elusive. This review brings a global state-of-the-art vision of the behavioral genetics of addiction and collaborates on formulation of new hypothesis to guide future work. © 2015 Society for the Study of Addiction.

  2. Alignment of single-case design (SCD) research with individuals who are deaf or hard of hearing with the what Works Clearinghouse standards for SCD research.

    Science.gov (United States)

    Wendel, Erica; Cawthon, Stephanie W; Ge, Jin Jin; Beretvas, S Natasha

    2015-04-01

    The authors assessed the quality of single-case design (SCD) studies that assess the impact of interventions on outcomes for individuals who are deaf or hard-of-hearing (DHH). More specifically, the What Works Clearinghouse (WWC) standards for SCD research were used to assess design quality and the strength of evidence of peer-reviewed studies available in the peer-reviewed, published literature. The analysis yielded four studies that met the WWC standards for design quality, of which two demonstrated moderate to strong evidence for efficacy of the studied intervention. Results of this review are discussed in light of the benefits and the challenges to applying the WWC design standards to research with DHH individuals and other diverse, low-incidence populations. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  3. Principle research on a single mass piezoelectric six-degrees-of-freedom accelerometer.

    Science.gov (United States)

    Liu, Jun; Li, Min; Qin, Lan; Liu, Jingcheng

    2013-08-16

    A signal mass piezoelectric six-degrees-of-freedom (six-DOF) accelerometer is put forward in response to the need for health monitoring of the dynamic vibration characteristics of high grade digitally controlled machine tools. The operating principle of the piezoelectric six-degrees-of-freedom accelerometer is analyzed, and its structure model is constructed. The numerical simulation model (finite element model) of the six axis accelerometer is established. Piezoelectric quartz is chosen for the acceleration sensing element and conversion element, and its static sensitivity, static coupling interference and dynamic natural frequency, dynamic cross coupling are analyzed by ANSYS software. Research results show that the piezoelectric six-DOF accelerometer has advantages of simple and rational structure, correct sensing principle and mathematic model, good linearity, high rigidity, and theoretical natural frequency is more than 25 kHz, no nonlinear cross coupling and no complex decoupling work.

  4. Principle Research on a Single Mass Piezoelectric Six-Degrees-of-Freedom Accelerometer

    Directory of Open Access Journals (Sweden)

    Jingcheng Liu

    2013-08-01

    Full Text Available A signal mass piezoelectric six-degrees-of-freedom (six-DOF accelerometer is put forward in response to the need for health monitoring of the dynamic vibration characteristics of high grade digitally controlled machine tools. The operating principle of the piezoelectric six-degrees-of-freedom accelerometer is analyzed, and its structure model is constructed. The numerical simulation model (finite element model of the six axis accelerometer is established. Piezoelectric quartz is chosen for the acceleration sensing element and conversion element, and its static sensitivity, static coupling interference and dynamic natural frequency, dynamic cross coupling are analyzed by ANSYS software. Research results show that the piezoelectric six-DOF accelerometer has advantages of simple and rational structure, correct sensing principle and mathematic model, good linearity, high rigidity, and theoretical natural frequency is more than 25 kHz, no nonlinear cross coupling and no complex decoupling work.

  5. Explaining variance and identifying predictors of children's communication via a multilevel model of single-case design research.

    Science.gov (United States)

    Ottley, Jennifer Riggie; Ferron, John M; Hanline, Mary Frances

    2016-06-01

    The purpose of this study was to explain the variability in data collected from a single-case design study and to identify predictors of communicative outcomes for children with developmental delays or disabilities (n = 4). Using SAS University Edition, we fit multilevel models with time nested within children. Children's initial levels of communication and teachers' frequency of strategy use when directed at the children predicted children's communicative outcomes. These results indicate that teachers' implementation of evidence-based communication strategies, when directed toward children with disabilities, and the interaction between their use of the strategies and children's initial levels of communication predict children's communicative outcomes. Implications for research and practice are provided.

  6. Treatment Recommendations for Single-Unit Crowns: Findings from The National Dental Practice-Based Research Network

    Science.gov (United States)

    McCracken, Michael S.; Louis, David R.; Litaker, Mark S.; Minyé, Helena M.; Mungia, Rahma; Gordan, Valeria V.; Marshall, Don G.; Gilbert, Gregg H.

    2016-01-01

    Background Objectives were to: (1) quantify practitioner variation in likelihood to recommend a crown; and (2) test whether certain dentist, practice, and clinical factors are significantly associated with this likelihood. Methods Dentists in the National Dental Practice-Based Research Network completed a questionnaire about indications for single-unit crowns. In four clinical scenarios, practitioners ranked their likelihood of recommending a single-unit crown. These responses were used to calculate a dentist-specific “Crown Factor” (CF; range 0–12). A higher score implies a higher likelihood to recommend a crown. Certain characteristics were tested for statistically significant associations with the CF. Results 1,777 of 2,132 eligible dentists responded (83%). Practitioners were most likely to recommend crowns for teeth that were fractured, cracked, endodontically-treated, or had a broken restoration. Practitioners overwhelmingly recommended crowns for posterior teeth treated endodontically (94%). Practice owners, Southwest practitioners, and practitioners with a balanced work load were more likely to recommend crowns, as were practitioners who use optical scanners for digital impressions. Conclusions There is substantial variation in the likelihood of recommending a crown. While consensus exists in some areas (posterior endodontic treatment), variation dominates in others (size of an existing restoration). Recommendations varied by type of practice, network region, practice busyness, patient insurance status, and use of optical scanners. Practical Implications Recommendations for crowns may be influenced by factors unrelated to tooth and patient variables. A concern for tooth fracture -- whether from endodontic treatment, fractured teeth, or large restorations -- prompted many clinicians to recommend crowns. PMID:27492046

  7. Treatment recommendations for single-unit crowns: Findings from The National Dental Practice-Based Research Network.

    Science.gov (United States)

    McCracken, Michael S; Louis, David R; Litaker, Mark S; Minyé, Helena M; Mungia, Rahma; Gordan, Valeria V; Marshall, Don G; Gilbert, Gregg H

    2016-11-01

    The objectives of this study were to quantify practitioner variation in likelihood to recommend a crown and test whether certain dentist, practice, and clinical factors are associated significantly with this likelihood. Dentists in The National Dental Practice-Based Research Network completed a questionnaire about indications for single-unit crowns. In 4 clinical scenarios, practitioners ranked their likelihood of recommending a single-unit crown. The authors used these responses to calculate a dentist-specific crown factor (range, 0-12). A higher score implied a higher likelihood of recommending a crown. The authors tested certain characteristics for statistically significant associations with the crown factor. A total of 1,777 of 2,132 eligible dentists (83%) responded. Practitioners were most likely to recommend crowns for teeth that were fractured, cracked, or endodontically treated or had a broken restoration. Practitioners overwhelmingly recommended crowns for posterior teeth treated endodontically (94%). Practice owners, practitioners in the Southwest, and practitioners with a balanced workload were more likely to recommend crowns, as were practitioners who used optical scanners for digital impressions. There is substantial variation in the likelihood of recommending a crown. Although consensus exists in some areas (posterior endodontic treatment), variation dominates in others (size of an existing restoration). Recommendations varied according to type of practice, network region, practice busyness, patient insurance status, and use of optical scanners. Recommendations for crowns may be influenced by factors unrelated to tooth and patient variables. A concern for tooth fracture-whether from endodontic treatment, fractured teeth, or large restorations-prompted many clinicians to recommend crowns. Copyright © 2016 American Dental Association. Published by Elsevier Inc. All rights reserved.

  8. A Meta-Analysis of Single Case Research Studies on Aided Augmentative and Alternative Communication Systems with Individuals with Autism Spectrum Disorders

    Science.gov (United States)

    Ganz, Jennifer B.; Earles-Vollrath, Theresa L.; Heath, Amy K.; Parker, Richard I.; Rispoli, Mandy J.; Duran, Jaime B.

    2012-01-01

    Many individuals with autism cannot speak or cannot speak intelligibly. A variety of aided augmentative and alternative communication (AAC) approaches have been investigated. Most of the research on these approaches has been single-case research, with small numbers of participants. The purpose of this investigation was to meta-analyze the single…

  9. Can teaching research methodology influence students' attitude toward science? Cohort study and nonrandomized trial in a single medical school.

    Science.gov (United States)

    Vujaklija, Ana; Hren, Darko; Sambunjak, Dario; Vodopivec, Ivana; Ivanis, Ana; Marusić, Ana; Marusić, Matko

    2010-02-01

    Medical teaching aims to develop attitudes and behaviors underlying professional competence of future physicians. We investigated whether a mandatory course on scientific methodology in the second study year could affect students' attitudes toward science in medicine. In a longitudinal study, students (n = 241) enrolling in 2001-2002 academic year at a single medical school were followed up until graduation in 2006-2007. Each year, they filled out a Likert-type questionnaire of 18 statements evaluating attitude toward science. Direct influence of the course on students' attitudes was tested in a nonrandomized controlled trial with the 2006-2007 second year student cohort. Positive students' attitudes toward science increased during study years (mean [SD] score of the maximum score of 90): from 57.6 (6.0) in the first to 69.8 (10.4) in the sixth year. There was a significant trend of increase in attitudes with the years of study (cubic trend by polynomial contrasts analysis, P = 0.011). Attendance of a course on research methodology significantly increased positive attitudes (score, 67.0 [7.0] before and 70.8 [7.5] after course, P = 0.032 vs control group), regardless of grade point average. The intervention had an effect even when the influence of the initial attitude was accounted for (F1,140 = 9.25, P = 0.003; analysis of covariance). The attitude changes after the course was greatest in students with low initial attitude scores (Spearman rinitial score, score difference, -0.44). Medical students have positive attitudes toward science and scientific method in medicine. Attendance of a course on research methodology had positive short-term effect on students' attitudes toward science. This positive effect should be maintained by vertical integration of the course in the medical curriculum.

  10. Changes in the lipid composition of blood under the influence of a single submaximal exercise capacity (experimental research.

    Directory of Open Access Journals (Sweden)

    Ermolaeva E.N.

    2015-06-01

    Full Text Available In acute physical exercise, there is a change in oxygen delivery working tissues, blood gas transport function and efficiency of the use of oxygen by cells in the process of metabolism, which is the basis for compensation for physical activities. Lipid metabolism plays an important role in the energy supply of muscle activity. The aim of our research is to study the effect of a single submaximal exercise capacity by changing the lipid profile of peripheral blood. Materials and Methods. The study was performed on 18 white rats. Model of acute exercise: animals swam 4 minutes with a load weighing 20% of body weight. Blood sampling was performed by intracardiac way, right after exercise. The blood lipid profile was determined. Results. In the experiment reported an increase in triglycerides, total cholesterol, very low-density lipoproteins, but the atherogenic ratio is maintained at the control values, due to a significant increase in the level of high-density lipoprotein. Conclusion. Acute submaximal exercise capacity by untrained body has an atherogenic effect. Working muscles during physical activity is a major consumer of free fatty acids, which are the source of atherogenic lipoprotein form of the very low and low density.

  11. Research report 24 single-family dwellings from the fifties. Annex; Onderzoekrapport 24 rijwoningen jaren '50. Bijlage

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-05-15

    This analysis is part of a coordinated series of studies for different residential building complexes of different corporations. This research report concerns the quick scan to decide on investments for the improvement of three single-family houses complexes, which were built in 1959. Based on four financial scenarios a framework is set up by means of which an integrated investment assessment can be made. In the study, scores are given for improving energy efficiency, reducing emission, quality of the construction, technical quality, urban and architectural quality, indoor environment, social aspects, etc. [Dutch] Deze analyse is onderdeel van een gecoordineerde serie onderzoeken voor verschillende complexen van verschillende corporaties. Dit onderzoeksrapport betreft de quickscan voor de investeringsafweging voor de verbetering van een drietal complexen van het type eengezinswoningen eind jaren vijftig. Op basis van vier financieel onderbouwde scenario's wordt het kader geschetst waarmee een integrale investeringsafweging kan worden gemaakt. In het onderzoek worden waarderingen gegeven voor de verbetering van de aspecten energiezuinigheid, uitstoot), bouwtechnisch kwaliteit, markttechnische kwaliteit, stedenbouwkundige en architectonische kwaliteit, binnenklimaat, sociale aspecten, etc.

  12. Influence of single-phase heat transfer correlations on safety analysis of research reactors with narrow rectangular fuel channels

    International Nuclear Information System (INIS)

    Rawashdeh, A.; Altamimi, R.; Lee, B.; Chung, Y. J.; Park, S.

    2013-01-01

    The influence of different single-phase heat transfer correlations on the fuel temperature and minimum critical heat flux ratio (MCHFR) during a typical accident of a 5 MW research reactor is investigated. A reactor uses plate type fuel, of which the cooling channels have a narrow rectangular shape. RELAP5/MOD3.3 tends to over-predict the Nusselt number (Nu) at a low Reynolds number (Re) region, and therefore the correlation set is modified to properly describe the thermal behavior at that region. To demonstrate the effect of Nu at a low-Re region on an accident analysis, a two-pump failure accident was chosen as a sample problem. In the accident, the downward core flow decreases by a pump coast-down, and then reverses upward by natural convection. During the pump coast-down and flow reversal, the flow undergoes a laminar flow regime which has a different Nu with respect to the correlation sets. Compared to the results by the original RELAP5/MOD3.3, the modified correlation set predicts the fuel temperature to be a little higher than the original value, and the MCHFR to be a little lower than the original value. Although the modified correlation set predicts the fuel temperature and the MCHFR to be less conservative than those calculated from the original correlation of RELAP5/MOD3.3, the maximum fuel temperature and the MCHFR still satisfy the safety acceptance criteria

  13. Research on the speed of light transmission in a dual-frequency laser pumped single fiber with two directions

    Science.gov (United States)

    Qiu, Wei; Liu, Jianjun; Wang, Yuda; Yang, Yujing; Gao, Yuan; Lv, Pin; Jiang, Qiuli

    2018-01-01

    In this article a general theory of the coherent population oscillation effect in an erbium-doped fiber at room temperature is presented. We use dual pumping light waves with a simplified two-level system. Thus the time delay equations can be calculated from rate equations and the transmission equation. Using numerical simulation, in the case of dual-frequency pump light waves (1480 nm and 980 nm) with two directions, we analyze the influence of the pump power ratio on the group speed of light propagation. In addition, we compare slow light propagation with a single-pumping light and slow light propagation with a dual-pumping light at room temperature. The discussion shows that a larger time delay of slow light propagation can be obtained with a dual-frequency pumping laser. Compared to previous research methods, a dual-frequency laser pumped fiber with two directions is more controllable. Moreover, we conclude that the group velocity of light can be varied by changing the pump ratio.

  14. Quality of Life from the Voting Booth: The Effect of Crime Rates and Income on Recent U.S. Presidential Elections

    Science.gov (United States)

    Hagerty, Michael R.

    2006-01-01

    Quality of Life (QOL) is often measured with surveys of citizen's satisfaction. In contrast, the current research uses already-existing voting data to infer citizens' perceptions of QOL. Under this model, citizens decide how much their QOL has improved (or declined) since the last election, and then vote to reward (or punish) the incumbent party…

  15. The influence of the design matrix on treatment effect estimates in the quantitative analyses of single-subject experimental design research.

    Science.gov (United States)

    Moeyaert, Mariola; Ugille, Maaike; Ferron, John M; Beretvas, S Natasha; Van den Noortgate, Wim

    2014-09-01

    The quantitative methods for analyzing single-subject experimental data have expanded during the last decade, including the use of regression models to statistically analyze the data, but still a lot of questions remain. One question is how to specify predictors in a regression model to account for the specifics of the design and estimate the effect size of interest. These quantitative effect sizes are used in retrospective analyses and allow synthesis of single-subject experimental study results which is informative for evidence-based decision making, research and theory building, and policy discussions. We discuss different design matrices that can be used for the most common single-subject experimental designs (SSEDs), namely, the multiple-baseline designs, reversal designs, and alternating treatment designs, and provide empirical illustrations. The purpose of this article is to guide single-subject experimental data analysts interested in analyzing and meta-analyzing SSED data. © The Author(s) 2014.

  16. Results of the 2015 Scoliosis Research Society Survey on Single Versus Dual Attending Surgeon Approach for Adult Spinal Deformity Surgery.

    Science.gov (United States)

    Scheer, Justin K; Sethi, Rajiv K; Hey, Lloyd A; LaGrone, Michael O; Keefe, Malla; Aryan, Henry E; Errico, Thomas J; Deviren, Vedat; Hart, Robert A; Lafage, Virginie; Schwab, Frank; Daubs, Michael D; Ames, Christopher P

    2017-06-15

    An electronic survey administered to Scoliosis Research Society (SRS) membership. To characterize surgeon practices and views regarding the use of two attending surgeons for adult spinal deformity (ASD) surgery. The use of two experienced attending surgeons can decrease the operative time, estimated blood loss, and perioperative complication rates. However, the current practice patterns for the use of two attending surgeons remains unknown. An electronic, 27-question survey regarding single/dual attending surgeons was administered to the SRS membership. Determinants included: surgeon/practice demographics, assistant type/level of training, and questions regarding use of two attending surgeons. Overall reporting and comparisons between groups were made: US versus international, academic versus private practice, and experience 15 years. A total of 199 surgeons responded from 27 different countries. Overall and between the groups, the respondents significantly reported believing that two attending spine surgeons improves safety, decreases complications, and improves outcomes (P < 0.01). Approximately, 67.3% reported using a second attending ≤25% of the time (33.2% do not), and 24.1% use one ≥51% of the time (similar between groups); 51.1% that have a second attending feel it's limited by reimbursement and access concerns and 71.9% have difficulty getting the second attending reimbursed. 72.3% use a second attending for ALL of the following reasons (no difference between groups): "it's safer/reduces complications," "it decreases operative time," "it decreases blood loss," "it results in improved outcomes," "it's less work and stress for me." If reimbursement was equal/assured for a second attending, 67.5% would use one "more often" or "always." The respondents feel that having a second attending surgeon improves patient care, however most do not use one often. Reasons include reimbursement/access concerns and the majority would use one if reimbursement was

  17. 75 FR 65638 - Award of a Single-source Program Expansion Supplement Grant to the Research Foundation of the...

    Science.gov (United States)

    2010-10-26

    ... training for middle managers and child welfare supervisors, administers BSW and MSW traineeships at... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Award of a Single... (SUNY) at Albany, NY, for the National Child Welfare Workforce Institute (NCWWI) AGENCY: Children's...

  18. Research on High Efficient Single-Phase Multi-Stage Interleaved Bridgeless PFC Frontend for Class-D Amplifiers

    DEFF Research Database (Denmark)

    Li, Qingnan; Thomsen, Ole Cornelius; Andersen, Michael A. E.

    2012-01-01

    In this paper, a 3.5kW single-phase high efficient interleaved Bridgeless PFC (IBPFC) is proposed for class-D amplifiers. This topology achieves a relatively higher efficiency in a wide output power range, which helps to reduce the energy consuming of the whole system. In addition, a detailed...

  19. A meta-analysis of single case research studies on aided augmentative and alternative communication systems with individuals with autism spectrum disorders.

    Science.gov (United States)

    Ganz, Jennifer B; Earles-Vollrath, Theresa L; Heath, Amy K; Parker, Richard I; Rispoli, Mandy J; Duran, Jaime B

    2012-01-01

    Many individuals with autism cannot speak or cannot speak intelligibly. A variety of aided augmentative and alternative communication (AAC) approaches have been investigated. Most of the research on these approaches has been single-case research, with small numbers of participants. The purpose of this investigation was to meta-analyze the single case research on the use of aided AAC with individuals with autism spectrum disorders (ASD). Twenty-four single-case studies were analyzed via an effect size measure, the Improvement Rate Difference (IRD). Three research questions were investigated concerning the overall impact of AAC interventions on targeted behavioral outcomes, effects of AAC interventions on individual targeted behavioral outcomes, and effects of three types of AAC interventions. Results indicated that, overall, aided AAC interventions had large effects on targeted behavioral outcomes in individuals with ASD. AAC interventions had positive effects on all of the targeted behavioral outcome; however, effects were greater for communication skills than other categories of skills. Effects of the Picture Exchange Communication System and speech-generating devices were larger than those for other picture-based systems, though picture-based systems did have small effects.

  20. Single-Case Design Research: Building the Evidence-Base in the Field of Education of Deaf and Hard of Hearing Students.

    Science.gov (United States)

    Cannon, Joanna E; Guardino, Caroline; Antia, Shirin D; Luckner, John L

    2016-01-01

    The field of education of deaf and hard of hearing (DHH) students has a paucity of evidence-based practices (EBPs) to guide instruction. The authors discussed how the research methodology of single-case design (SCD) can be used to build EBPs through direct and systematic replication of studies. An overview of SCD research methods is presented, including an explanation of how internal and external validity issues are addressed, and why SCD is appropriate for intervention research with DHH children. The authors then examine the SCD research in the field according to quality indicators (QIs; at the individual level and as a body of evidence) to determine the existing evidence base. Finally, future replication areas are recommended to fill the gaps in SCD research with students who are DHH in order to add to the evidence base in the field.

  1. Measurement of extravascular lung water using the single indicator method in patients: research and potential clinical value.

    Science.gov (United States)

    Brown, Lisa M; Liu, Kathleen D; Matthay, Michael A

    2009-10-01

    Extravascular lung water includes all of the fluid within the lung but outside of the vasculature. Lung water increases as a result of increased hydrostatic vascular pressure or from an increase in lung endothelial and epithelial permeability or both. Experimentally, extravascular lung water has been measured gravimetrically. Clinically, the chest radiograph is used to determine whether extravascular lung water is present but is an insensitive instrument for determining the quantity of lung water. Bedside measurement of extravascular lung water in patients is now possible using a single indicator thermodilution method. This review critically evaluates the experimental and clinical evidence supporting the potential value of measuring extravascular lung water in patients using the single indicator method.

  2. Perceptual Perspective Taking in Children Who Are Blind: The State of Research and a Single-Case Study

    Science.gov (United States)

    Brambring, Michael

    2005-01-01

    Perceptual perspective taking is regarded as a major milestone in sociocognitive development that sighted children have generally mastered by the age of 4-5 years. In children who are blind, however, most prior research reports a strong developmental delay of several years compared with sighted peers. After examining the current state of research,…

  3. Research

    African Journals Online (AJOL)

    abp

    175-7. PubMed | Google Scholar. 2. Barretti P, Moraes TM, Camargo CH, Caramori JC, Mondelli AL,. Montelli AC, et al. Peritoneal dialysis-related peritonitis due to. Staphylococcus aureus: a single-center experience over 15.

  4. Social anthropological and interdisciplinary research on the conversion of electrically heated single family houses to heating by combined pellet-solar systems

    International Nuclear Information System (INIS)

    Henning, Annette

    2004-01-01

    The social anthropological research presented here is part of the interdisciplinary research project PESTO, which focuses on the (partial or complete) conversion of single family houses from electric heating to heating by combined pellet-solar heating systems. Basic to this research is the assumption that it is more likely that energy conversions are carried through, and that they are successful on a long-term basis, if the new products are designed to fit as well as possible into the everyday lives of people. The anthropological interest in the project can be divided into two parts; motives for or against a conversion among men and women in Swedish households, and product design and placement in (previously) electrically heated single-family houses. Literature studies and semi-structured qualitative interviews are the main methods used in the anthropological part of the project. During the next 3-year project period, these investigations will be used to support information and marketing, and to formulate recommendations for conversion practice of electrically heated single-family houses to combined pellet-solar heating. (Author)

  5. [Argentina, Brazil and Mexico. Biomedical research and the defense of a single standard of attention in developing countries].

    Science.gov (United States)

    Angeles-Llerenas, Angélica; Bello, María Alejandra; Dirce, Guilhem; Salinas, Mario Alberto

    2004-01-01

    In the Helsinki Declaration, which established the ethical principles for research with human subjects, article 5 states, "...concern about the well-being of human beings should always come before the interests of science and of society..." Research proposals should include this commitment, both in developed and developing countries. In countries like Argentina, Brazil and Mexico, much of the population experience situations of great injustice, including a lack of equal access to health care. In some cases, sectors of the pharmaceutical industry may see these deficiencies as offering opportunities for carrying out research and achieving economic profits, something which carries the risk of perpetuating and even intensifying the unjust situations and violations of human rights--these population groups already suffer from. This situation implies the need for commitment to and ethical reflection upon human rights related to health. Agreements are needed between the actors involved in health research: sources of funding, researchers, public policy makers, and the study subjects themselves, in order to protect the latter's rights, including continuity of medical treatment for research subjects, when necessary.

  6. Research on Single-Phase PWM Converter with Reverse Conducting IGBT Based on Loss Threshold Desaturation Control

    Directory of Open Access Journals (Sweden)

    Xianjin Huang

    2017-11-01

    Full Text Available In the application of vehicle power supply and distributed power generation, there are strict requirements for the pulse width modulation (PWM converter regarding power density and reliability. When compared with the conventional insulated gate bipolar transistor (IGBT module, the Reverse Conducting-Insulated Gate Bipolar Transistor (RC-IGBT with the same package has a lower thermal resistance and higher current tolerance. By applying the gate desaturation control, the reverse recovery loss of the RC-IGBT diode may be reduced. In this paper, a loss threshold desaturation control method is studied to improve the output characteristics of the single-phase PWM converter with a low switching frequency. The gate desaturation control characteristics of the RC-IGBT’s diode are studied. A proper current limit is set to avoid the ineffective infliction of the desaturation pulse, while the bridge arm current crosses zero. The expectation of optimized loss decrease is obtained, and the better performance for the RC-IGBTs of the single-phase PWM converter is achieved through the optimized desaturation pulse distribution. Finally, the improved predictive current control algorithm that is applied to the PWM converter with RC-IGBTs is simulated, and is operated and tested on the scaled reduced power platform. The results prove that the gate desaturation control with the improved predictive current algorithm may effectively improve the RC-IGBT’s characteristics, and realize the stable output of the PWM converter.

  7. PAINT SPRAY BOOTH MODIFICATIONS FOR RECIRCULATION VENTILATION

    Science.gov (United States)

    The control of emissions from spray painting operations has historically been cost prohibitive, due to the high exhaust flow rates coupled with low volatile organic compound (VOC) and hazardous air pollutant (HAP) Concentrations. Past studies, conducted by the U.S. EPA and U.S. ...

  8. Experimental and Numerical Research of Stress-Strain State of Homogeneous Soil Massif at Interaction with Single Barrette

    Science.gov (United States)

    Ter-Martirosyan, Z. G.; Ter-Martirosyan, A. Z.; Sidorov, V. V.

    2017-11-01

    Deep foundations are used for the design of high-rise buildings due to a large pressure transfer on the soil base. The foundations of buildings sometimes use barrettes which are able to perceive significant vertical and horizontal loads due to improved lateral surface. Barrettes have increased load bearing capacity as compared with large diameter piles. In modern practice the interaction between barrettes and soil is investigated by analytical and numerical methods and has no sufficient experimental confirmation. The review of experimental methods for the research of the intense stress-strain state of the uniform soil massif at interaction with elements of a deep foundation is provided in this article. Experimental research are planned with the use of laboratory stand for the purpose of qualitative data obtaining on the interaction barrettes with an assessment of a settlement model adequacy and also at the research of the intense stress-strain state by numerical methods.

  9. Production of well defined chemically pure single crystals of rare-earth and actinide compounds for solid state research

    International Nuclear Information System (INIS)

    Vogt, O.; Spirlet, J.C.

    1987-01-01

    Today the understanding of delicate problems such as phase transitions or very low temperature phenomena depend on measurements which are very sensitive to the quality of the sample. Since the magnetic moments of rare-earths and actinides are usually anisotropic all experiments on magnetic properties require single crystals. The usual choice for ultrapurification are physical methods such as sublimation, vacuum melting, zone refining and electrotransport. Work has to be done under UHV conditions. Crystal growth is hampered by the high reactivity. For actinides toxicity and radioactivity are a further important handicap. Methods for crystal growth are solution growth, mineralization, Czochralski or Bridgman technique and zone melting. Crucible free methods are always preferable. (orig.)

  10. Research of all-optical ultra-wideband triplet signal source based on a single semiconductor optical amplifier

    Science.gov (United States)

    Xue, Fei; Li, Pei-li; Zheng, Jia-jin; Wang, Li-li; Liang, Wei-kang

    2013-07-01

    A novel scheme for all-optical ultra-wideband triplet signal pulse generation based on the cross-gain modulation (XGM) in a single semiconductor optical amplifier (SOA) is demonstrated. In this scheme, only one optical source and one SOA are needed, so the configuration is simple. Due to only one wavelength is included in the generated triplet pulse, no time difference between output signal light and probe light is introduced during the transmission process. By using the software of Optisystem 7.0, the impacts of the input signal width, the optical power and the wavelength of the optical source on the generated triplet pulse are numerically simulated and studied. The results show that the proposed scheme has better triplet signal pulse when the input signal pulse width is larger, and it is insensitive to the wavelength change within a certain range.

  11. Experimental research on single-phase heat transfer characteristics in a vertical circular tube under marine conditions

    International Nuclear Information System (INIS)

    Du Sijia; Zhang Hong; Jia Baoshan

    2011-01-01

    Experiments have been conducted to study the heat transfer characteristics of single-phase forced circulation when the test tube was under different marine conditions. The experiments measured the wall temperature of test tube to calculate the heat transfer coefficients at different circumferential places. When the test tube was under inclined conditions, the heat transfer coefficient increased at downside and decreased at upside of test tube because of buoyancy effect. When the test tube was under rolling conditions, the heat transfer coefficients fluctuated with the rolling motions, and the Coriolis force dominated the heat transfer fluctuation during the rolling motion. CFD method was used to simulate the heat transfer phenomena under marine conditions, and the results were accord to the experimental phenomena. (authors)

  12. Research activity on NaxCoO2 single crystals: A brief review on optical conductivity and metamagnetic transition phenomenon

    Directory of Open Access Journals (Sweden)

    N.L. Wang and J.L. Luo

    2005-01-01

    Full Text Available NaxCoO2 material is of great interest because of its rich electronic phase diagram, as well as for displaying superconductivity when intercalated with water. This paper briefly reviews our research activity on its optical properties and a metamagnetic transition phenomenon.

  13. Research

    African Journals Online (AJOL)

    abp

    2015-09-09

    Sep 9, 2015 ... Orthopaedics and Traumatology, Faculty of Medicine, Adiyaman University, 02040 Adiyaman, Turkey,3Department of Orthopedics and. Traumatology, Umraniye Research and Education Hospital, 34899 Istanbul, Turkey, 4Department of Orthopedics and Traumatology, Umraniye. Research and Education ...

  14. Colleagues as Change Agents: How Department Networks and Opinion Leaders Influence Teaching at a Single Research University.

    Science.gov (United States)

    Andrews, T C; Conaway, E P; Zhao, J; Dolan, E L

    2016-01-01

    Relationships with colleagues have the potential to be a source of support for faculty to make meaningful change in how they teach, but the impact of these relationships is poorly understood. We used a mixed-methods approach to investigate the characteristics of faculty who provide colleagues with teaching resources and facilitate change in teaching, how faculty influence one another. Our exploratory investigation was informed by social network theory and research on the impact of opinion leaders within organizations. We used surveys and interviews to examine collegial interactions about undergraduate teaching in life sciences departments at one research university. Each department included discipline-based education researchers (DBERs). Quantitative and qualitative analyses indicate that DBERs promote changes in teaching to a greater degree than other departmental colleagues. The influence of DBERs derives, at least partly, from a perception that they have unique professional expertise in education. DBERs facilitated change through coteaching, offering ready and approachable access to education research, and providing teaching training and mentoring. Faculty who had participated in a team based-teaching professional development program were also credited with providing more support for teaching than nonparticipants. Further research will be necessary to determine whether these results generalize beyond the studied institution. © 2016 T. C. Andrews et al. CBE—Life Sciences Education © 2016 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  15. Research

    African Journals Online (AJOL)

    The research methodology module was reviewed as part of the overall revision of the undergraduate physiotherapy curriculum of ... Structuring the research methodology module using an EBP teaching framework prepares students to formulate a research question, effectively ... manage, and organise bibliographic citations.

  16. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-05-13

    May 13, 2015 ... Systems (SEEDS)-INDEPTH Network Accra, Ghana, 3KEMRI/Wellcome Trust Research Programme, The Centre of Geographical Medicine Research-. Coast, Kilifi, Kenya, 4Population Health Sciences/Research Support Unit, Faculty of Health Sciences, Aga Khan University- East Africa, Nairobi,. Kenya ...

  17. Research

    African Journals Online (AJOL)

    research process, as part of which students must find and appraise evidence from research.[5] This highlights that teaching research methodology is inclined towards equipping students ... Students believed that evidence-based practice was vital, yet their understanding of the concept was restricted when compared with the.

  18. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-03-02

    Mar 2, 2015 ... this program provided short-term and long-term research training to. US infectious disease fellows who would work on collaborative research projects with Kenyan trainees. Since the program began in. 1988, there have been 56 US trainees, and 13 of these continue to collaborate with Kenyan researchers.

  19. Research

    African Journals Online (AJOL)

    raoul

    2012-01-20

    Jan 20, 2012 ... Urhobo/isoko ethnic groups in Delta state and the Bini in Edo state recording the highest prevalence of lymphoid malignancies. ... from a single institution in Thailand over a 15 year period, there was an increase in lymphoma cases from 73 cases per year in the first series to. 189 cases per year in the ...

  20. Research

    African Journals Online (AJOL)

    abp

    2015-10-22

    Oct 22, 2015 ... modifying the method used by Fitzgerald et al. [6], we decided for the criteria returning to work by knee function test, single-legged hop test score, Lachman test, anterior drawer test and pivot-shift test in miners. This study was approved by the institutional ethical committee; all patients were informed and the ...

  1. Research

    African Journals Online (AJOL)

    abp

    2016-05-13

    May 13, 2016 ... Breast cancer patients' presentation for oncological treatment: a single centre study ... demographics, breast cancer burden and health care giver presentation variables were analysed for causal factors of seeking medical help and .... acquisition, and literature search, definition of intellectual content,.

  2. Research

    African Journals Online (AJOL)

    This was a single-centre, cross-sectional study, using the Postgraduate Hospital Educational Environment Measure (PHEEM). The ... 2 Department of Oral and Maxillofacial Surgery and Oral Pathology, Faculty of Dentistry, College of Medical Sciences, University of Maiduguri, Nigeria .... had more positives than negatives.

  3. Research

    African Journals Online (AJOL)

    abp

    2012-07-27

    Jul 27, 2012 ... adult Cameroonian patients on HAART between 2003 and 2009 at the Douala General Hospital was done in search of reported HAART-associated. Adverse Drug .... All patients who were on single or two drug antiretroviral therapy for prevention of mother to child transmission during the study period were ...

  4. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-11-18

    Nov 18, 2015 ... randomized into three treatment arms using random numbers obtained from random number table to be treated with a single dose (400mg) of different brands (Albenz-400 (India, Manufactured by Sterling Lab), Ovis (South Korea, Manufactured by DAE HWA. PHARM.CO.,LTD) and Wormin A 200 (Ethiopia, ...

  5. Stroke research questions: a nursing perspective.

    Science.gov (United States)

    Rowat, Anne; Lawrence, Maggie; Horsburgh, Dorothy; Legg, Lynn; Smith, Lorraine N

    stroke is a national research priority. However, in the literature there is still minimal systematic investigation of stroke nursing - especially practice. The aim of this study was to explore stroke nurses' research priorities through a series of focus groups. the study was qualitative and involved focus groups (n = 7) with registered nurses working in stroke care settings and who were members of the Scottish Stroke Nurses Forum. Data were analysed to identify conceptual categories, which were found to relate to the categories defined by Kirkevold (1997) and Booth (2001). five priority areas for stroke nursing were described: preventive/conserving; supporting/consoling; restorative; integrative; and service structure/systems. by consulting stroke nurses it can be ensured that future research truly reflects the nature of nursing care and is of particular relevance to stroke nursing practice. The development of research evidence-base in stroke nursing will lead to increased knowledge, a better quality of care and ultimately better outcomes for patients.

  6. Non-Stationary Single-Channel Queuing System Features Research in Context of Number of Served Queries

    Directory of Open Access Journals (Sweden)

    Porshnev Sergey

    2017-01-01

    Full Text Available This work devoted to researching of mathematical model of non-stationary queuing system (NQS. Arrival rate in studied NQS λ(t is similar to rate which observed in practice in a real access control system of objects of mass events. Dependence of number of serviced requests from time was calculated. It is proven that the ratio value of served requests at the beginning of event to all served requests described by a deterministic function, depending on the average service rate μ¯$\\bar \\mu $ and the maximum value of the arrival rate function λ(t.

  7. Research

    African Journals Online (AJOL)

    abp

    2015-01-19

    Jan 19, 2015 ... in Cameroon. This study aimed at examining the sexual risk behaviours of high school female learners in Mbonge subdivision of rural Cameroon. ... Despite a wealth of research on youth, little research has been done on the sexual ..... Behavior, and Mental Health: a study of University Students in. Uganda.

  8. researchers

    African Journals Online (AJOL)

    African Sociological Review, 7, (2), 2003, pp.149-161. RESEARCH REPORTS. Revisiting “insiders' and 'outsiders' as social researchers. Marlize Rabe .... use of knowledgeable fieldworkers is then examined by focussing on the work ... A study by Russell (1995:p.95–97) on the long-term effects of incestuous abuse.

  9. Research

    African Journals Online (AJOL)

    2014-05-06

    May 6, 2014 ... facilitate and support articulation between the ECT mid-level worker qualification and the professional B EMC degree. Methods. The researchers used an exploratory, sequential mixed-method design, which is characterised by a qualitative phase of research followed by a quantitative phase. This design is ...

  10. Research on Discretization PI Control Technology of Single-Phase Grid-Connected Inverter with LCL Filter

    Directory of Open Access Journals (Sweden)

    Jianke Li

    2014-01-01

    Full Text Available Compared with L-type filter, LCL-type filter is more suitable for high-power low-switching frequency applications with reducing the inductance, improving dynamic performance. However, the parameter design for the LCL filter is more complex due to the influence of the controller response performance of the converter. If the harmonic current around switching frequency can be fully suppressed, it is possible for inverter to decrease the total inductance as well as the size and the cost. In this paper, the model of the LCL filter is analyzed and numerical algorithms are adopted to analyze the stability of the closed-loop control system and stable regions are deduced with different parameters of LCL filter. Then, the minimum sampling frequencies are deduced with different conditions. Simulation and experimental results are provided to validate the research on the generating mechanism for the unstable region of sampling frequency.

  11. CMDX©-based single source information system for simplified quality management and clinical research in prostate cancer.

    Science.gov (United States)

    Eminaga, Okyaz; Abbas, Mahmoud; Hinkelammert, Reemt; Titze, Ulf; Bettendorf, Olaf; Eltze, Elke; Ozgür, Enver; Semjonow, Axel

    2012-12-03

    Histopathological evaluation of prostatectomy specimens is crucial to decision-making and prediction of patient outcomes in prostate cancer (PCa). Topographical information regarding PCa extension and positive surgical margins (PSM) is essential for clinical routines, quality assessment, and research. However, local hospital information systems (HIS) often do not support the documentation of such information. Therefore, we investigated the feasibility of integrating a cMDX-based pathology report including topographical information into the clinical routine with the aims of obtaining data, performing analysis and generating heat maps in a timely manner, while avoiding data redundancy. We analyzed the workflow of the histopathological evaluation documentation process. We then developed a concept for a pathology report based on a cMDX data model facilitating the topographical documentation of PCa and PSM; the cMDX SSIS is implemented within the HIS of University Hospital Muenster. We then generated a heat map of PCa extension and PSM using the data. Data quality was assessed by measuring the data completeness of reports for all cases, as well as the source-to-database error. We also conducted a prospective study to compare our proposed method with recent retrospective and paper-based studies according to the time required for data analysis. We identified 30 input fields that were applied to the cMDX-based data model and the electronic report was integrated into the clinical workflow. Between 2010 and 2011, a total of 259 reports were generated with 100% data completeness and a source-to-database error of 10.3 per 10,000 fields. These reports were directly reused for data analysis, and a heat map based on the data was generated. PCa was mostly localized in the peripheral zone of the prostate. The mean relative tumor volume was 16.6%. The most PSM were localized in the apical region of the prostate. In the retrospective study, 1623 paper-based reports were transferred

  12. Research

    African Journals Online (AJOL)

    abp

    Research Team in Maternal and Child Health and Nutrition, Mohammed V. University, Rabat, Morocco. Key words: Breast cancer, risk factor, case-control study. Received: 04/01/2016 - Accepted: 17/03/2016 - Published: 06/05/2016. Abstract.

  13. Research

    Science.gov (United States)

    Mathematics Teaching, 1973

    1973-01-01

    Implications for teachers from Piagetian-oriented piagetian-oriented research on problem solving reported in an article by Eleanor Duckworth are presented. Edward de Bono's Children Solve Problems,'' a collection of examples, is also discussed. (MS)

  14. Research

    African Journals Online (AJOL)

    their academic performance, capabilities and functionings. At a tertiary educational level ... Research indicates that academic stressors, living circumstances, working conditions and where students undertake leisure activities affect academic performance .... Insufficient sleep, mild exhaustion, poor eating habits and little ...

  15. Research

    International Nuclear Information System (INIS)

    1999-01-01

    Subjects covered in this section are: (1) PCAST panel promotes energy research cooperation; (2) Letter issued by ANS urges funding balance in FFTF restart consideration and (3) FESAC panel releases report on priorities and balance

  16. Evidence for single-dose protection by the bivalent HPV vaccine-Review of the Costa Rica HPV vaccine trial and future research studies.

    Science.gov (United States)

    Kreimer, Aimée R; Herrero, Rolando; Sampson, Joshua N; Porras, Carolina; Lowy, Douglas R; Schiller, John T; Schiffman, Mark; Rodriguez, Ana Cecilia; Chanock, Stephen; Jimenez, Silvia; Schussler, John; Gail, Mitchell H; Safaeian, Mahboobeh; Kemp, Troy J; Cortes, Bernal; Pinto, Ligia A; Hildesheim, Allan; Gonzalez, Paula

    2018-01-20

    The Costa Rica Vaccine Trial (CVT), a phase III randomized clinical trial, provided the initial data that one dose of the HPV vaccine could provide durable protection against HPV infection. Although the study design was to administer all participants three doses of HPV or control vaccine, 20% of women did not receive the three-dose regimens, mostly due to involuntary reasons unrelated to vaccination. In 2011, we reported that a single dose of the bivalent HPV vaccine could be as efficacious as three doses of the vaccine using the endpoint of persistent HPV infection accumulated over the first four years of the trial; findings independently confirmed in the GSK-sponsored PATRICIA trial. Antibody levels after one dose, although lower than levels elicited by three doses, were 9-times higher than levels elicited by natural infection. Importantly, levels remained essentially constant over at least seven years, suggesting that the observed protection provided by a single dose might be durable. Much work has been done to assure these non-randomized findings are valid. Yet, the group of recipients who received one dose of the bivalent HPV vaccine in the CVT and PATRICIA trials was small and not randomly selected nor blinded to the number of doses received. The next phase of research is to conduct a formal randomized, controlled trial to evaluate the protection afforded by a single dose of HPV vaccine. Complementary studies are in progress to bridge our findings to other populations, and to further document the long-term durability of antibody response following a single dose. Published by Elsevier Ltd.

  17. Recommendations for collaborative paediatric research including biobanking in Europe: a Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) initiative.

    Science.gov (United States)

    Kuemmerle-Deschner, Jasmin B; Hansmann, Sandra; Wulffraat, Nico M; Vastert, Sebastiaan J; Hens, Kristien; Anton, Jordi; Avcin, Tadej; Martini, Alberto; Koné-Paut, Isabelle; Uziel, Yosef; Ravelli, Angelo; Wouters, Carine; Shaw, David; Özen, Seza; Eikelberg, Andreas; Prakken, Berent J; Ruperto, Nicolino; Horneff, Gerd; Constantin, Tamas; Beresford, Michael W; Sikken, Marijn; Foster, Helen E; Haug, Iris; Schuller, Sabrina; Jägle, Christine; Benseler, Susanne M

    2018-03-01

    Innovative research in childhood rheumatic diseases mandates international collaborations. However, researchers struggle with significant regulatory heterogeneity; an enabling European Union (EU)-wide framework is missing. The aims of the study were to systematically review the evidence for best practice and to establish recommendations for collaborative research. The Paediatric Rheumatology European Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) project enabled a scoping review and expert discussion, which then informed the systematic literature review. Published evidence was synthesised; recommendations were drafted. An iterative review process and consultations with Ethics Committees and European experts for ethical and legal aspects of paediatric research refined the recommendations. SHARE experts and patient representatives vetted the proposed recommendations at a consensus meeting using Nominal Group Technique. Agreement of 80% was mandatory for inclusion. The systematic literature review returned 1319 records. A total of 223 full-text publications plus 22 international normative documents were reviewed; 85 publications and 16 normative documents were included. A total of 21 recommendations were established including general principles (1-3), ethics (4-7), paediatric principles (8 and 9), consent to paediatric research (10-14), paediatric databank and biobank (15 and 16), sharing of data and samples (17-19), and commercialisation and third parties (20 and 21). The refined recommendations resulted in an agreement of >80% for all recommendations. The SHARE initiative established the first recommendations for Paediatric Rheumatology collaborative research across borders in Europe. These provide strong support for an urgently needed European framework and evidence-based guidance for its implementation. Such changes will promote research in children with rheumatic diseases. © Article author(s) (or their employer(s) unless otherwise

  18. Research

    African Journals Online (AJOL)

    ebutamanya

    2016-03-24

    Mar 24, 2016 ... national non-governmental organization (NGO) ”Arc en Ciel„. This. NGO, which is familiar with research activities, identified the MSM community leaders in the .... whom there is an emotional attachment) in both homosexual and heterosexual populations [14, 19]. Like other reports from. Cameroon [19] and ...

  19. Research

    African Journals Online (AJOL)

    raoul

    2012-01-11

    Jan 11, 2012 ... 1MPH Programme, Department of Community Medicine, University of Zimbabwe, Zimbabwe, 2Department of Epidemiology and Disease Control,. Ministry ... Pan African Medical Journal. 2012; 11: ..... Mufuta Tshimanga: Had oversight of all the stages of the research and critically reviewed the final draft for.

  20. Research

    African Journals Online (AJOL)

    raoul

    2011-08-25

    Aug 25, 2011 ... euthanasia were also queried. Data was analyzed using Epidata, SPSS 16.0 and Microsoft Excel. Results: Thirty-eight (97.4%) of thirty-nine institutions reported using animals for education and/or research. Thirty (76.9%) institutions reported using analgesics or anesthetics on a regular basis. Thirteen ...

  1. Research

    African Journals Online (AJOL)

    abp

    2016-02-01

    Feb 1, 2016 ... University Hospital, DK-5000 Odense, Denmark, 3Center for Global Health, Institute of Clinical Research, University of Southern Denmark, DK-5000. Odense .... BHP is a Danish-Guinean Demographic Surveillance Site with a study-area .... variables such as age groups, previous military duty, history of.

  2. Research

    African Journals Online (AJOL)

    Research. May 2016, Vol. 8, No. 1 AJHPE 37. Students who enrol in occupational therapy (OT) at the. University of Kwa Zulu-Natal (UKZN), Durban, South Africa ... The latter may include becoming familiar with the disintegrating social systems in primary .... They also lacked the skills needed to adapt sessions and failed to ...

  3. Research

    African Journals Online (AJOL)

    raoul

    2011-12-14

    Dec 14, 2011 ... skills through hands-on application of epidemiology to real public health issues. For the most part, residents carry out research projects in priority areas of the districts they are attached, often under direct supervision of the local or provincial health leaders [2]. In Africa, these programs formed a networking ...

  4. Research

    African Journals Online (AJOL)

    abp

    2014-03-21

    Mar 21, 2014 ... Published in partnership with the African Field Epidemiology Network (AFENET). (www.afenet.net). Research ... were intervention strategies for primary health care delivery at the district and community levels ..... to be a gap between policy formation and implementation as only immunization services are.

  5. Research

    African Journals Online (AJOL)

    abp

    2013-03-05

    Mar 5, 2013 ... food market) [10]. There are few studies that provide data on NCDs from Africa and these are mainly from South Africa [11]. In the same vein, research efforts in The .... males, in view of the relationships between obesity, physical inactivity and .... pronged intervention strategies-epidemiological surveillance,.

  6. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-11-23

    Nov 23, 2015 ... 1Amref Health Africa, P.O Box 2773 Dar es Salaam, Tanzania, 2Kilimanjaro Reproductive Health Program, Moshi, Tanzania, 3Population Services. International, Nairobi .... testing, HIV testing history and HIV test results. ..... due to differences in the research designs, nature of population and sample size ...

  7. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-06-22

    Jun 22, 2015 ... collaboration with Makerere University, School of Public Health. We acknowledge The Family Health Research and Development Centre. (FHRDC) Uganda. Supported by Bill & Melinda Gates Institute for. Population & Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, ...

  8. Research

    African Journals Online (AJOL)

    abp

    2016-04-14

    Apr 14, 2016 ... Methods. Study design: A mixed method cross-sectional design using both quantitative and qualitative research methods as described by. Hanson et al [33] was employed. Settings: The study was based on data from the midterm evaluation that was conducted between August-December 2012 involving ...

  9. Research

    African Journals Online (AJOL)

    The study followed a qualitative research design using semi-structured interviews with full-time SA- or foreign-qualified specialists at. Kimberley Hospital ... average number of weekly hours spent on undergraduate student training ... The best place to learn is at the bedside; a student should see the patient, read up and ...

  10. Research

    African Journals Online (AJOL)

    the importance of the learning setting (curriculum context), a capability approach to learning (the process), and the production of expert generalists. (the outcome) .... including communication, learning transfer, teamwork, self-confidence, and reciprocal and effective practice.[6-8] Research also shows that PAL provides a.

  11. Research

    African Journals Online (AJOL)

    raoul

    2011-11-14

    Nov 14, 2011 ... Data were collected between February and March 2010 using a questionnaire, designed by the researcher. It comprised two sections; the ..... Bazant ES, Koenig MA, Fotso J-C, Mills S. Women's Use of Private and Government Health Facilities for Childbirth in Nairobi's Informal. Settlements. Stud Fam Plann ...

  12. Research

    African Journals Online (AJOL)

    Research. This article provides a detailed description of the development of an evaluation matrix that represents the organising structure for evaluating the impact of the interdisciplinary health-promotion course on multiple stakeholders. The evaluation was designed to answer the questions relating to the perceptions and ...

  13. Research

    African Journals Online (AJOL)

    2017-03-18

    Mar 18, 2017 ... promote CPD by working in partnership with employers, academic institutions ... SORK, employers and institutions of higher education all have a responsibility towards the culture of lifelong learning. As the ... further approved by the Higher Degrees and Research Ethics Committees of the University of ...

  14. Research

    African Journals Online (AJOL)

    abp

    2014-08-29

    Aug 29, 2014 ... Page number not for citation purposes ... Pan African Medical Journal – ISSN: 1937- 8688 (www.panafrican-med-journal.com). Published in partnership with the African Field Epidemiology Network (AFENET). (www.afenet.net). Research .... and education, hence a higher risk of morbidity and mortality and a.

  15. Research

    African Journals Online (AJOL)

    tions as their reality.[14]. Research context. At Stellenbosch University (SU), Cape Town,. SA, final-year physiotherapy students each spend. 6 weeks at a community site learning to integrate and apply the principles of PHC and community- based rehabilitation. Approximately 5 - 10 clients are seen in their homes per week.

  16. Research

    African Journals Online (AJOL)

    the classroom.[9] Cognitive learning is achieved when students can make connections among and interpret different aspects of a subject to apply what they have learned in other fields of ... the effect of the field trips on the students' perceptions. ... researcher in higher education teaching and learning facilitated the data-.

  17. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-12-02

    Dec 2, 2015 ... It is an important aspect of quality of life which is often neglected by people in this age group, attending physicians and the society as a whole. The study was aimed at determining ... or a trained research assistant for those who could neither read nor write. Consenting individuals above this age who have ...

  18. Research

    African Journals Online (AJOL)

    abp

    2014-01-31

    Jan 31, 2014 ... by Hazarika in a population-based study in India. The researcher noted that patients' preference to the private health facilities was due mainly to their dissatisfaction with the services in the public health facilities [11]. Furthermore, the quality of the services in the private health facilities could also be a major ...

  19. Research

    African Journals Online (AJOL)

    abp

    2017-11-30

    Nov 30, 2017 ... Authors' contributions. All the authors have read and agreed to the final manuscript. Acknowledgments. The author was supported by a postdoctoral fellowship awarded by the South African National Research Foundation (NRF). The content of this manuscript does not necessarily represent the official views.

  20. Research

    African Journals Online (AJOL)

    abp

    2017-12-05

    Dec 5, 2017 ... work is properly cited. Pan African Medical Journal – ISSN: 1937- 8688 ... an unfinished business as dozens of studies reveal millions of children worldwide have not yet benefited from the .... regions included in the research site [24]. Results. In the final analysis, three working themes were generated.

  1. Research

    African Journals Online (AJOL)

    Workshop on {topic}; research project; clinical practical experience. Outputs. Tangible products/by-products of activities (but not whether students learned anything). Certificates of completion; records of actions by participants (i.e. log books); number of students at clinical site. Intermediate outcomes Learning connected to ...

  2. Research

    African Journals Online (AJOL)

    abp

    2017-05-18

    May 18, 2017 ... available to populations of developing countries [2-5]. In 2013, in. Western and Central Europe and ..... initiation among the infected persons in the community. Addressing stigma and educating ... Lifespan/Tufts/Brown Center for AIDS Research (P30AI042853). Tables. Table 1: Baseline characteristics of ...

  3. Research

    African Journals Online (AJOL)

    2014-05-18

    May 18, 2014 ... Research. Practice within the clinical arena is recognised as the best means of socialising students into the physiotherapy profession[1-5] and is known to ..... A ect. Intervention. Overall preparedness. Fig. 1. Means and 95% CIs of the mean scores of each component (n=58; 9 missing). There is a significant ...

  4. Research

    African Journals Online (AJOL)

    YouTube, TED and other podcast websites. Other researchers have also documented their procedures. Corl et al.[5] describe the basic process of producing a podcast, and Jham et al.[6] list a number of universities actively doing podcasts. Besides the lecture podcasts, we have also captured numerous clinical.

  5. ASM Inaugural Lecture 2010: Single crystal X-ray structural determination: A powerful technique for natural products research and drug discovery

    International Nuclear Information System (INIS)

    Fun Hoong Kun; Chantrapromma, S.; Boonnak, N.; Lee, V.S.

    2010-01-01

    Drug discovery from natural products resources have been extensively studied worldwide because natural products with their great structural diversity have traditionally provided most of the drugs in use. They offer major opportunities for finding novel low molecular weight leading-structures that are active against a wide range of assay targets. The most important step in the discovery process is the identification of compounds with interesting biological activity. Single crystal X-ray structure determination is a powerful technique for natural products research and drug discovery. The detailed three-dimensional structures that emerge can be co-related to the activities to these structures. In this article the following is presented: (i) co-crystal and disorder structures; (ii) determination of absolute configuration and (iii) the ability to distinguish between whether a natural product compound is a natural product or a natural product artifact. All these three properties are unique to the technique of single crystal X-ray structure determination. Case (iii) was demonstrated with a compound containing a chromene ring, namely macluraxanthone (which was isolated from Cratoxylum formosum subsp. pruniflorum, a Thai medicinal plant). (author)

  6. Moderation of effects of AAC based on setting and types of aided AAC on outcome variables: an aggregate study of single-case research with individuals with ASD.

    Science.gov (United States)

    Ganz, Jennifer B; Rispoli, Mandy J; Mason, Rose Ann; Hong, Ee Rea

    2014-06-01

    The purpose of this meta-analysis was to evaluate the potential moderating effects of intervention setting and type of aided augmentative and alternative communication (AAC) on outcome variables for students with autism spectrum disorders. Improvement rate difference, an effect size measure, was used to calculate aggregate effects across 35 single-case research studies. Results indicated that the largest effects for aided AAC were observed in general education settings. With respect to communication outcomes, both speech generating devices (SGDs) and the Picture Exchange Communication System (PECS) were associated with larger effects than other picture-based systems. With respect to challenging behaviour outcomes, SGDs produced larger effects than PECS. This aggregate study highlights the importance of considering intervention setting, choice of AAC system and target outcomes when designing and planning an aided AAC intervention.

  7. A meta-analysis of single-case research on behavior contracts: effects on behavioral and academic outcomes among children and youth.

    Science.gov (United States)

    Bowman-Perrott, Lisa; Burke, Mack D; de Marin, Sharon; Zhang, Nan; Davis, Heather

    2015-03-01

    The purpose of this meta-analysis was to quantitatively summarize the single-case research (SCR) literature on the use of behavior contracts with children and youth. This study examined the efficacy of behavior contracts on problem behaviors and academic behaviors across 18 SCR studies. Academic and behavioral outcomes were examined for 58 children and youth ages 5 to 21 using the TauU effect size index. Results indicated the overall moderate effect of the use of behavior contracts was ES = .57 (95% confidence interval [CI95] = [0.55, 0.58]) with a range of effects across studies (ES = .27 to ES = 1.00). Moderator analyses indicated that behavior contracts are beneficial for students regardless of grade level, gender, or disability status. Findings suggest that the intervention is more effective in reducing inappropriate behaviors than increasing appropriate behaviors, and that academic outcomes are positively affected by behavior contracting. © The Author(s) 2014.

  8. International trade shows: Structure, strategy and performance of exhibitors at individual booths vs. joint booths

    DEFF Research Database (Denmark)

    Hansen, Kåre

    2000-01-01

    of exhibitors at the international food shows SIAL (Paris) and ANUGA (Cologne) showed several significant differences with regard to structure and strategy. However, no significant differences in the performance assessments between the two partici-pation modes were found. The findings have important...... implications for exhibitors at interna-tional trade shows and export marketing programmes and other marketing programmes offering services to international trade show exhibitors....

  9. Setting up a Prospective Thyroid Biobank for Translational Research: Practical Approach of a Single Institution (2004-2009, Pasteur Hospital, Nice, France).

    Science.gov (United States)

    Lassalle, Sandra; Hofman, Véronique; Ilie, Marius; Butori, Catherine; Bonnetaud, Christelle; Gaziello, Marie Clotilde; Selva, Eric; Gavric-Tanga, Virginie; Guevara, Nicolas; Castillo, Laurent; Santini, José; Chabannon, Christian; Hofman, Paul

    2011-03-01

    In the last few years, conditions for setting up a human biobank in France have been upgraded by taking into account (1) the new laws and regulations that integrate the ethical and societal dimension of biobanking and delineate the risks for patients associated with the procurement of human cells and tissues, (2) the increasing request by scientists for human samples with proven biological quality and sophisticated sets of annotations, including information produced through the evergrowing use of molecular biology in pathology, and (3) establishment of procedures concerning the safety of the personnel working with biological products. For this purpose, health authorities and national research institutes in France have provided significant support for the set up of biobanks. The present work was conducted to describe how we set up a biobank targeting diseases of a specific organ (thyroid gland), with the aim of rapidly developing translational research projects. The prospective experience of a single institution (Pasteur Hospital, Nice, France) over a 6-year period (2004-2009) is presented from the practical point of view of a surgical pathology laboratory. We describe different procedures required to obtain high-quality thyroid biological resources and clinical annotations. The procedures were established for the management of biological products obtained from 1454 patients who underwent thyroid surgery. The preanalytical steps leading to the storage of frozen specimens were carried out in parallel with diagnostic procedures. As the number of international networks for research programs using biological products is steadily increasing, it is crucial to harmonize the procedures used by biobanks. In this regard, the described thyroid biobank has been set up using criteria established by the French National Cancer Institute (Institut National du Cancer) to guarantee the quality of different collections stored in biobanks.

  10. The Power of Flash Mob Research: Conducting a Nationwide Observational Clinical Study on Capillary Refill Time in a Single Day.

    Science.gov (United States)

    Alsma, Jelmer; van Saase, Jan L C M; Nanayakkara, Prabath W B; Schouten, W E M Ineke; Baten, Anique; Bauer, Martijn P; Holleman, Frits; Ligtenberg, Jack J M; Stassen, Patricia M; Kaasjager, Karin H A H; Haak, Harm R; Bosch, Frank H; Schuit, Stephanie C E

    2017-05-01

    Capillary refill time (CRT) is a clinical test used to evaluate the circulatory status of patients; various methods are available to assess CRT. Conventional clinical research often demands large numbers of patients, making it costly, labor-intensive, and time-consuming. We studied the interobserver agreement on CRT in a nationwide study by using a novel method of research called flash mob research (FMR). Physicians in the Netherlands were recruited by using word-of-mouth referrals, conventional media, and social media to participate in a nationwide, single-day, "nine-to-five," multicenter, cross-sectional, observational study to evaluate CRT. Patients aged ≥ 18 years presenting to the ED or who were hospitalized were eligible for inclusion. CRT was measured independently (by two investigators) at the patient's sternum and distal phalanx after application of pressure for 5 s (5s) and 15 s (15s). On October 29, 2014, a total of 458 investigators in 38 Dutch hospitals enrolled 1,734 patients. The mean CRT measured at the distal phalanx were 2.3 s (5s, SD 1.1) and 2.4 s (15s, SD 1.3). The mean CRT measured at the sternum was 2.6 s (5s, SD 1.1) and 2.7 s (15s, SD 1.1). Interobserver agreement was higher for the distal phalanx (κ value, 0.40) than for the sternum (κ value, 0.30). Interobserver agreement on CRT is, at best, moderate. CRT measured at the distal phalanx yielded higher interobserver agreement compared with sternal CRT measurements. FMR proved a valuable instrument to investigate a relatively simple clinical question in an inexpensive, quick, and reliable manner. Copyright © 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

  11. Effectiveness of a brief school-based body image intervention 'Dove Confident Me: Single Session' when delivered by teachers and researchers: Results from a cluster randomised controlled trial.

    Science.gov (United States)

    Diedrichs, Phillippa C; Atkinson, Melissa J; Steer, Rebecca J; Garbett, Kirsty M; Rumsey, Nichola; Halliwell, Emma

    2015-11-01

    This study evaluated a 90-min single session school-based body image intervention (Dove Confident Me: Single Session), and investigated if delivery could be task-shifted to teachers. British adolescents (N = 1707; 11-13 years; 50.83% girls) participated in a cluster randomised controlled trial [lessons as usual control; intervention teacher-led (TL); intervention researcher-led (RL)]. Body image, risk factors, and psychosocial and disordered eating outcomes were assessed 1-week pre-intervention, immediate post-intervention, and 4-9.5 weeks follow-up. Multilevel mixed-models showed post-intervention improvements for intervention students relative to control in body esteem (TL; girls only), negative affect (TL), dietary restraint (TL; girls only), eating disorder symptoms (TL), and life engagement (TL; RL). Awareness of sociocultural pressures increased at post-intervention (TL). Effects were small-medium in size (ds 0.19-0.76) and were not maintained at follow-up. There were no significant differences between conditions at post or follow-up on body satisfaction, appearance comparisons, teasing, appearance conversations and self-esteem. The intervention had short-term benefits for girls' body image and dietary restraint, and for eating disorder symptoms and some psychosocial outcomes among girls and boys. A multi-session version of the intervention is likely to be necessary for sustained improvements. Teachers can deliver this intervention effectively with minimal training, indicating broader scale dissemination is feasible. ISRCTN16782819. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  12. Research Research

    African Journals Online (AJOL)

    Research. May 2014, Vol. 6, No. 1 AJHPE 33. Research. Currently, radiography students are faced with the challenge of having to learn factual information, while ... A descriptive exploratory research design was used to collect both ..... Creswell J. Research Design: Quantitative, Qualitative and Mixed Methods Approaches.

  13. Single molecules and nanotechnology

    CERN Document Server

    Vogel, Horst

    2007-01-01

    This book focuses on recent advances in the rapidly evolving field of single molecule research. These advances are of importance for the investigation of biopolymers and cellular biochemical reactions, and are essential to the development of quantitative biology. Written by leading experts in the field, the articles cover a broad range of topics, including: quantum photonics of organic dyes and inorganic nanoparticles their use in detecting properties of single molecules the monitoring of single molecule (enzymatic) reactions single protein (un)folding in nanometer-sized confined volumes the dynamics of molecular interactions in biological cells The book is written for advanced students and scientists who wish to survey the concepts, techniques and results of single molecule research and assess them for their own scientific activities.

  14. Single Policy Study

    DEFF Research Database (Denmark)

    Kronsell, Annica; Manners, Ian James

    2015-01-01

    Single policy studies are the most common form of European Union (EU) research. Single policy studies are widely used to understand the role of the EU in a wide variety of sectors, together with their development over time, and often offer public policy prescriptions. This chapter discusses the r...... Policy (CSDP). The examples are illustrative of how single policy studies can be designed to use different approaches in the analysis: multiple streams approach to policy-making; a comparative hypothesis testing; and feminist institutional theory.......Single policy studies are the most common form of European Union (EU) research. Single policy studies are widely used to understand the role of the EU in a wide variety of sectors, together with their development over time, and often offer public policy prescriptions. This chapter discusses...... the relevance of single policy studies in EU research and give examples of how such research can be designed and carried out. The chapter reviews three examples of single policy studies using different methods based on EU environmental policy, the EU biofuels directive, and the EU Common Security and Defence...

  15. Caught between a rock and a hard place: An intrinsic single-case study of nurse researchers’ experiences of the presence of a nursing research culture in clinical practice

    DEFF Research Database (Denmark)

    Bøttcher Berthelsen, Connie; Hølge-Hazelton, Bibi

    2017-01-01

    for the skills of health professionals and evidence-based practice. However, the utilization of nursing research in clinical practice is still limited. DESIGN: Intrinsic single-case study design underlined by a constructivist perspective. METHODS: Data were produced through a focus group interview with seven......: 'Caught between a rock and a hard place' was constructed as the main theme describing how nurse researchers in clinical positions experience the presence of a nursing research culture in clinical practice. The main theme was supported by three sub-themes: Minimal academic tradition affects nursing...

  16. Research on absolute measurement of 222Rn/220Rn concentrations based on a single small scintillation cell and delay-time method

    International Nuclear Information System (INIS)

    Zhou Jianbo; Zhao Xiuliang; Yu Hong; Xiao Yongjun; Wu Yongyan

    2009-01-01

    A single small scintillation with delay-time method is used to measure radon and thoron concentrations in their mixed atmosphere-of absolute measurement of radon and thoron concentrations was discussed. The conditions of using radon to test this method was described and a experiment was designed to prove it. Compare to the reference number, Its margin of error was -2.9%∼+3.4%, and the best time of the measurement of radon was 10-45 minutes. In conclusion, a single small scintillation cell could be used for absolute measurement radon and thoron concentrations. (authors)

  17. Researching research

    DEFF Research Database (Denmark)

    Pais, Alexandre; Valero, Paola

    2012-01-01

    We discuss contemporary theories in mathematics education in order to do research on research. Our strategy consists of analysing discursively and ideologically recent key publications addressing the role of theory in mathematics education research. We examine how the field fabricates its object...... of research by deploying Foucault’s notion of bio-politics - mainly to address the object “learning” - and Žižek’s ideology critique - to address the object “mathematics”. These theories, which have already been used in the field to research teaching and learning, have a great potential to contribute...... to a reflexivity of research on its discourses and effects. Furthermore, they enable us to present a clear distinction between what has been called the sociopolitical turn in mathematics education research and what we call a positioning of mathematics education (research) practices in the Political....

  18. School-Based Peer-Related Social Competence Interventions for Children with Autism Spectrum Disorder: A Meta-Analysis and Descriptive Review of Single Case Research Design Studies

    Science.gov (United States)

    Whalon, Kelly J.; Conroy, Maureen A.; Martinez, Jose R.; Werch, Brittany L.

    2015-01-01

    The purpose of this review was to critically examine and summarize the impact of school-based interventions designed to facilitate the peer-related social competence of children with autism spectrum disorder (ASD). Reviewed studies employed a single-case experimental design, targeted peer-related social competence, included children 3-12 years old…

  19. Reliability of 3-Dimensional Measures of Single-Leg Cross Drop Landing Across 3 Different Institutions: Implications for Multicenter Biomechanical and Epidemiological Research on ACL Injury Prevention.

    Science.gov (United States)

    DiCesare, Christopher A; Bates, Nathaniel A; Barber Foss, Kim D; Thomas, Staci M; Wordeman, Samuel C; Sugimoto, Dai; Roewer, Benjamin D; Medina McKeon, Jennifer M; Di Stasi, Stephanie; Noehren, Brian W; Ford, Kevin R; Kiefer, Adam W; Hewett, Timothy E; Myer, Gregory D

    2015-12-01

    Anterior cruciate ligament (ACL) injuries are physically and financially devastating but affect a relatively small percentage of the population. Prospective identification of risk factors for ACL injury necessitates a large sample size; therefore, study of this injury would benefit from a multicenter approach. To determine the reliability of kinematic and kinetic measures of a single-leg cross drop task across 3 institutions. Controlled laboratory study. Twenty-five female high school volleyball players participated in this study. Three-dimensional motion data of each participant performing the single-leg cross drop were collected at 3 institutions over a period of 4 weeks. Coefficients of multiple correlation were calculated to assess the reliability of kinematic and kinetic measures during the landing phase of the movement. Between-centers reliability for kinematic waveforms in the frontal and sagittal planes was good, but moderate in the transverse plane. Between-centers reliability for kinetic waveforms was good in the sagittal, frontal, and transverse planes. Based on these findings, the single-leg cross drop task has moderate to good reliability of kinematic and kinetic measures across institutions after implementation of a standardized testing protocol. Multicenter collaborations can increase study numbers and generalize results, which is beneficial for studies of relatively rare phenomena, such as ACL injury. An important step is to determine the reliability of risk assessments across institutions before a multicenter collaboration can be initiated.

  20. Clinical evaluation of 1,132 zirconia-based single crowns: a retrospective cohort study from the AIOP clinical research group.

    Science.gov (United States)

    Monaco, Carlo; Caldari, Mauro; Scotti, Roberto

    2013-01-01

    The aim of this retrospective cohort study was to gather the outcomes of zirconia single crowns made by 16 members of the Italian Academy of Prosthetic Dentistry (AIOP) over a time period of up to 5 years. A total of 398 patients treated in private practices with 1,132 zirconia-based single-crown restorations made on natural teeth from January 2005 to July 2010 were included. Three hundred forty-three anterior restorations (30.3%) and 789 posterior crowns (69.7%) were made with 16 types of zirconia, using primarily chamfer or knife-edge tooth preparation, and examined according to the esthetic, functional, and biologic criteria. To evaluate the relationship of parafunction with mechanical failure, patients with clenching or bruxism were not excluded from the study group. The cumulative survival rate of all restorations was 98.1%, while the cumulative success rate was 94.3%. Functional criteria had the highest number of failures. The odds ratio (OR) for all restorations was calculated to clarify the relationship between patients who were subject/not subject to parafunctions and technical complications; the OR was 2.60. An association between parafunction and mechanical failure was found in patients with severe parafunction. Porcelain-veneered zirconia single crowns with chamfer and knife-edge preparations showed good clinical results over a period of up to 5 years. Technical complications were few and were limited primarily to patients with parafunction.

  1. Single-Phase PLLs

    DEFF Research Database (Denmark)

    Golestan, Saeed; Guerrero, Josep M.; Quintero, Juan Carlos Vasquez

    2017-01-01

    Single-phase phase-locked loops (PLLs) are popular for the synchronization and control of single-phase gridconnected converters. They are also widely used for monitoring and diagnostic purposes in the power and energy areas. In recent years, a large number of single-phase PLLs with different...... structures and properties have been proposed in the literature. The main aim of this paper is to provide a review of these PLLs. To this end, the single-phase PLLs are first classified into two major categories: 1) power-based PLLs (pPLLs), and 2) quadrature signal generation-based PLLs (QSG......-PLLs). The members of each category are then described and their pros and cons are discussed. This work provides a deep insight into characteristics of different single-phase PLLs and, therefore, can be considered as a reference for researchers and engineers....

  2. Understanding implementation and change in complex interventions. From single- to multi-methodological research on the promotion of youths’ participation in physical education

    DEFF Research Database (Denmark)

    Agergaard, Sine; Dankers, Silke; Munk, Mette

    2018-01-01

    Existing studies on complex interventions aiming to promote youths’ participation in physical education (PE) appear to be predominantly single-methodological. The aim of this article is to examine the benefits and challenges of evaluating an intervention to increase youths’ participation...... and experiences of social inclusion in the PE context using a multi-method approach integrating quantitative and qualitative approaches. The multi-method approach allowed an integration of the findings with regard to the implementation as well as the effect of the intervention. First of all, standardized...

  3. Comparative research on “high currents” induced by single event latch-up and transient-induced latch-up

    International Nuclear Information System (INIS)

    Chen Rui; Han Jian-Wei; Zheng Han-Sheng; Yu Yong-Tao; Shangguang Shi-Peng; Feng Guo-Qiang; Ma Ying-Qi

    2015-01-01

    By using the pulsed laser single event effect facility and electro-static discharge (ESD) test system, the characteristics of the “high current”, relation with external stimulus and relevance to impacted modes of single event latch-up (SEL) and transient-induced latch-up (TLU) are studied, respectively, for a 12-bit complementary metal–oxide semiconductor (CMOS) analog-to-digital converter. Furthermore, the sameness and difference in physical mechanism between “high current” induced by SEL and that by TLU are disclosed in this paper. The results show that the minority carrier diffusion in the PNPN structure of the CMOS device which initiates the active parasitic NPN and PNP transistors is the common reason for the “high current” induced by SEL and for that by TLU. However, for SEL, the minority carrier diffusion is induced by the ionizing radiation, and an underdamped sinusoidal voltage on the supply node (the ground node) is the cause of the minority carrier diffusion for TLU. (paper)

  4. Research on modeling of the agile satellite using a single gimbal magnetically suspended CMG and the disturbance feedforward compensation for rotors.

    Science.gov (United States)

    Cui, Peiling; Yan, Ning

    2012-12-12

    The magnetically suspended Control Moment Gyroscope (CMG) has the advantages of long-life, micro-vibration and being non-lubricating, and is the ideal actuator for agile maneuver satellite attitude control. However, the stability of the rotor in magnetic bearing and the precision of the output torque of a magnetically suspended CMG are affected by the rapid maneuvers of satellites. In this paper, a dynamic model of the agile satellite including a magnetically suspended single gimbal control moment gyroscope is built and the equivalent disturbance torque effected on the rotor is obtained. The feedforward compensation control method is used to depress the disturbance on the rotor. Simulation results are given to show that the rotor displacement is obviously reduced.

  5. Research on Modeling of the Agile Satellite Using a Single Gimbal Magnetically Suspended CMG and the Disturbance Feedforward Compensation for Rotors

    Directory of Open Access Journals (Sweden)

    Ning Yan

    2012-12-01

    Full Text Available The magnetically suspended Control Moment Gyroscope (CMG has the advantages of long-life, micro-vibration and being non-lubricating, and is the ideal actuator for agile maneuver satellite attitude control. However, the stability of the rotor in magnetic bearing and the precision of the output torque of a magnetically suspended CMG are affected by the rapid maneuvers of satellites. In this paper, a dynamic model of the agile satellite including a magnetically suspended single gimbal control moment gyroscope is built and the equivalent disturbance torque effected on the rotor is obtained. The feedforward compensation control method is used to depress the disturbance on the rotor. Simulation results are given to show that the rotor displacement is obviously reduced.

  6. School-based peer-related social competence interventions for children with autism spectrum disorder: a meta-analysis and descriptive review of single case research design studies.

    Science.gov (United States)

    Whalon, Kelly J; Conroy, Maureen A; Martinez, Jose R; Werch, Brittany L

    2015-06-01

    The purpose of this review was to critically examine and summarize the impact of school-based interventions designed to facilitate the peer-related social competence of children with autism spectrum disorder (ASD). Reviewed studies employed a single-case experimental design, targeted peer-related social competence, included children 3-12 years old with an ASD, and took place in school settings. Articles were analyzed descriptively and using the evaluative method to determine study quality. Additionally, effect size estimates were calculated using nonoverlap of all pairs method and Tau-U. A total of 37 studies including 105 children were reviewed. Overall, ES estimates ranged from weak to strong, but on average, the reviewed interventions produced a moderate to strong effect, and quality ratings were generally in the acceptable to high range. Findings suggest that children with ASD can benefit from social skill interventions implemented with peers in school settings.

  7. Efficacy of behavioral interventions for reducing problem behavior in persons with autism: an updated quantitative synthesis of single-subject research.

    Science.gov (United States)

    Heyvaert, Mieke; Saenen, Lore; Campbell, Jonathan M; Maes, Bea; Onghena, Patrick

    2014-10-01

    Problem or challenging behaviors are highly prevalent among persons with autism and bring along major risks for the individual with autism and his/her family. In order to reduce the problem behavior, several behavioral interventions are used. We conducted a quantitative synthesis of single-subject studies to examine the efficacy of behavioral interventions for reducing problem behavior in persons with autism. Two hundred and thirteen studies representing 358 persons with autism met the inclusion criteria and were included in the statistical analyses. Overall, we found that behavioral interventions were on average effective in reducing problem behavior in individuals with autism, but some interventions were significantly more effective than others. The results further showed that the use of positive (nonaversive) behavioral interventions was increasing over time. The behavioral interventions were on average equally effective regardless of the type of problem behavior that was targeted. Interventions preceded by a functional analysis reduced problem behavior significantly more than interventions not preceded by a functional analysis. Finally, treatment and experimental characteristics, but not participant characteristics, were statistically significant moderators of the behavioral treatment effectiveness. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. Implementasi dan Evaluasi Kinerja Multi Input SingleOutput Orthogonal Frequency Division Multiplexing (MISO OFDM Menggunakan Wireless Open Access Research Platform (WARP

    Directory of Open Access Journals (Sweden)

    Galih Permana Putra

    2017-01-01

    Full Text Available Teknologi komunikasi nirkabel terus berkembang untuk memenuhi kebutuhan manusia akan koneksi informasi yang cepat, pengiriman data yang berkapasitas besar dan dapat diandalkan. Di dalam proses tersebut banyak sekali gangguan yang dapat mempengaruhi penurunan kinerja komunikasi diantaranya adalah multipath fading [1]. Multi Input Single Output (MISO merupakan salah satu teknik space diversity yang menggunakan banyak antena dengan tujuan untuk mengatasi multipath fading. Adapun pada proses transmisi digunakan teknik Orthogonal Frequency-Division Multiplexing (OFDM yang bertujuan memberikan keuntungan dalam hal efisiensi pada saat transmisi data dan mampu menghindari Inter Simbol Interference (ISI. Pada penelitian ini akan dibandingkan kinerja sistem MISO OFDM dan SISO OFDM yang akan disimulasikan dan di implementasikan pada modul Wireless Open Access Penelitian Platform (WARP untuk mengevaluasi kinerja BER sebagai fungsi dari daya pancar dan jarak variasi. Parameter yang digunakan di dalam pengukuran berdasarkan IEEE 802.11 a/g karena menggunakan frekuensi 2,4 Ghz. Terdapat dua skema pengukuran yaitu SISO OFDM dan MISO OFDM dengan variasi jarak 4,6 dan 8 meter dengan variasi daya pancar -35 s/d -4 dBm dengan peningkatan gain 5 kali secara berkala. Dari dua skema yang dilaksanakan dapat disimpulkan bahwa semakin jauh jarak antara pemancar dan penerima maka dibutuhkan penambahan gain untuk menjaga kualitas data yang dikirimkan. Disamping itu, terdapat perbedaan nilai gain untuk mencapai nilai BER = dibutuhkan penambahan gain = - 33 sedangkan pada SISO OFM dibutuhkan penambahan gain = -18.

  9. Always single and single again women: a qualitative study.

    Science.gov (United States)

    Lewis, K G; Moon, S

    1997-04-01

    What is it like to be a single woman today? Are the experiences of women who have always been single different from those who find themselves single again after having been married? How can family therapists promote the development of single women both individually and relationally? The purpose of this phenomenological, multiple-case study was to investigate perceptions of being single among heterosexual single women between the ages of 30 and 65. Nine focus group interviews and a semistructured, mailed questionnaire were used to collect the data. Constant comparative analyses were used to develop the findings. The findings were organized around the most salient theme that emerged from the analyses: single women have unresolved or unrecognized ambivalences about being single. This overarching theme was supported by three subassertions: (a) single women are aware of both the advantages and the drawbacks of being single; (b) single women are ambivalent about the reasons for their singleness; (c) although content with being single, many women simultaneously experience feelings of loss and grief. Implications for the clinical practice of family therapy and future research on single women are discussed.

  10. Single Item Inventory Models

    NARCIS (Netherlands)

    E.M. Bazsa-Oldenkamp; P. den Iseger

    2001-01-01

    textabstractThis paper extends a fundamental result about single-item inventory systems. This approach allows more general performance measures, demand processes and order policies, and leads to easier analysis and implementation, than prior research. We obtain closed form expressions for the

  11. A systematic study on the influencing parameters and improvement of quantitative analysis of multi-component with single marker method using notoginseng as research subject.

    Science.gov (United States)

    Wang, Chao-Qun; Jia, Xiu-Hong; Zhu, Shu; Komatsu, Katsuko; Wang, Xuan; Cai, Shao-Qing

    2015-03-01

    A new quantitative analysis of multi-component with single marker (QAMS) method for 11 saponins (ginsenosides Rg1, Rb1, Rg2, Rh1, Rf, Re and Rd; notoginsenosides R1, R4, Fa and K) in notoginseng was established, when 6 of these saponins were individually used as internal referring substances to investigate the influences of chemical structure, concentrations of quantitative components, and purities of the standard substances on the accuracy of the QAMS method. The results showed that the concentration of the analyte in sample solution was the major influencing parameter, whereas the other parameters had minimal influence on the accuracy of the QAMS method. A new method for calculating the relative correction factors by linear regression was established (linear regression method), which demonstrated to decrease standard method differences of the QAMS method from 1.20%±0.02% - 23.29%±3.23% to 0.10%±0.09% - 8.84%±2.85% in comparison with the previous method. And the differences between external standard method and the QAMS method using relative correction factors calculated by linear regression method were below 5% in the quantitative determination of Rg1, Re, R1, Rd and Fa in 24 notoginseng samples and Rb1 in 21 notoginseng samples. And the differences were mostly below 10% in the quantitative determination of Rf, Rg2, R4 and N-K (the differences of these 4 constituents bigger because their contents lower) in all the 24 notoginseng samples. The results indicated that the contents assayed by the new QAMS method could be considered as accurate as those assayed by external standard method. In addition, a method for determining applicable concentration ranges of the quantitative components assayed by QAMS method was established for the first time, which could ensure its high accuracy and could be applied to QAMS methods of other TCMs. The present study demonstrated the practicability of the application of the QAMS method for the quantitative analysis of multi

  12. Are plant-based functional foods better choice against cancer than single phytochemicals? A critical review of current breast cancer research.

    Science.gov (United States)

    Kapinova, Andrea; Stefanicka, Patrik; Kubatka, Peter; Zubor, Pavol; Uramova, Sona; Kello, Martin; Mojzis, Jan; Blahutova, Dana; Qaradakhi, Tawar; Zulli, Anthony; Caprnda, Martin; Danko, Jan; Lasabova, Zora; Busselberg, Dietrich; Kruzliak, Peter

    2017-12-01

    Breast cancer is the most common malignancy in women worldwide. Over 90% of all breast cancer cases are of different 'sporadic' cell types, thus placing emphasis on the need for breast cancer prevention and new effective treatment strategies. In recent years, pre-clinical research provides growing evidence regarding the beneficial action of bioactive plant-derived substances - phytochemicals, on multiple cancer-related biological pathways. The important natural source of various phytochemicals with anti-oncogenic properties are plant-based functional foods. It is hypothesized that a significant anti-tumour activity of plant-based functional foods are the result of a combination of various phytochemicals rather than an isolated agent. The mixture of phytochemicals with various biological activities present in whole foods could have additive or synergistic effects against carcinogenesis. Clinically, it is very important to compare the effect of the isolated phytochemicals against the mixture of phytochemicals present in specific plant-based functional foods. Therefore, the purpose of this review article is to compare anticancer activities of isolated phytochemicals and plant-based functional foods for the prevention and therapy of breast carcinoma. Our conclusion supports the hypothesis that a mixture of wide range of phytochemicals with a plethora of biological activities present in whole plant-derived foods could have additive or synergistic effects against breast cancer. Although, the lack of parallel comparative studies between whole natural foods versus isolated plant compounds limits our conclusion, future pre-clinical and clinical studies evaluating this issue is required. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  13. Telecommuting from an Electronic Cottage: Negotiating Potholes and Toll Booths.

    Science.gov (United States)

    Craumer, Pat; Marshall, Lucy

    1997-01-01

    Though telecommuting has been found to increase employee productivity as much as 20%, not all employers and workers embrace the concept. This article examines the pros and cons of telecommuting by presenting case studies of remote employment and a self-owned business. Provides a bibliography of print and nonprint resources for remote working and a…

  14. METROLOGICAL CONTROL OF LIGHTING IN STANDARDS BOOTHS FOR VISUAL APPRAISAL

    OpenAIRE

    MIGUEL DE FREITAS CHRISTINO

    2004-01-01

    Não obstante os sofisticados avanços em tecnologias ópticas, ainda não existem fontes de luz artificial capazes de simular de forma adequada a luz do dia natural. Alcançar um padrão de iluminação como este representará uma redução nos custos de produção, em função de retrabalhos gerados por avaliações visuais pouco confiáveis, e nas divergências comerciais relacionadas a produtos que têm como característica de controle a cor, tais como artigos têxteis, gráficos,...

  15. A comparison of single-suture and double-suture incision closures in seaward-migrating juvenile Chinook salmon implanted with acoustic transmitters: implications for research in river basins containing hydropower structures

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Richard S.; Deters, Katherine A.; Cook, Katrina V.; Eppard, M. B.

    2013-07-15

    Reductions in the size of acoustic transmitters implanted in migrating juvenile salmonids have resulted in the ability to make shorter incisions that may warrant using only a single suture for closure. However, it is not known if one suture will sufficiently hold the incision closed, particularly when outward pressure is placed on the surgical site such as when migrating fish experience pressure changes associated with passage at hydroelectric dams. The objective of this research was to evaluate the effectiveness of single-suture incision closures on juvenile Chinook salmon (Oncorhynchus tshawytscha). Juvenile Chinook salmon were surgically implanted with a 2012 Juvenile Salmon Acoustic Telemetry System (JSATS) transmitter (0.30 g) and a passive integrated transponder tag (0.10 g) and incisions were closed with either one suture or two sutures. Mortality and tag retention were monitored and fish were examined after 7 and 14 days to evaluate tissue responses. In a separate experiment, surgically implanted fish were exposed to simulated turbine passage and then examined for expulsion of transmitters, expulsion of viscera through the incision, and mortal injury. With incisions closed using a single suture, there was no mortality or tag loss and similar or reduced tissue reaction compared to incisions closed with two sutures. Further, surgery time was significantly reduced when one suture was used, which leads to less handling and reduced stress. No tags were expelled during pressure scenarios and expulsion of viscera only occurred in two non-mortally injured fish (5%) with single sutures that were also exposed to very high pressure changes. No viscera expulsion was present in fish exposed to pressure scenarios likely representative of hydroturbine passage at many Columbia River dams (e.g. <2.7 ratio of pressure change; an acclimation pressure of 146.2 absolute kpa and a lowest exposure pressure of ~ 53.3 absolute kpa). Based on these results, we recommend the use of a

  16. Single Purpose Satellite Systems

    OpenAIRE

    Watkins, Warren

    1989-01-01

    This paper examines the need for tactically responsive space systems capable of supporting battlefield and fleet commanders. Terminology used to describe this category of satellite system varies according to organization or agency. The Defense Advanced Research Projects Agency's Lightsat, the Naval Space Command's SPINSAT, and the Air Force Space Command s TACSAT, are reviewed. The United State Space Command's space support mission IS addressed and the role single-purpose satellites can play ...

  17. Constructing the single woman in therapy

    OpenAIRE

    Reynolds, Jill

    2002-01-01

    This article brings a social constructionist perspective to discussion of the therapeutic literature on singleness and draws on the author's research interviews with single women to consider how therapists might make use of this perspective in their practice.

  18. Mixed methods research.

    Science.gov (United States)

    Halcomb, Elizabeth; Hickman, Louise

    2015-04-08

    Mixed methods research involves the use of qualitative and quantitative data in a single research project. It represents an alternative methodological approach, combining qualitative and quantitative research approaches, which enables nurse researchers to explore complex phenomena in detail. This article provides a practical overview of mixed methods research and its application in nursing, to guide the novice researcher considering a mixed methods research project.

  19. Single frequency semiconductor lasers

    CERN Document Server

    Fang, Zujie; Chen, Gaoting; Qu, Ronghui

    2017-01-01

    This book systematically introduces the single frequency semiconductor laser, which is widely used in many vital advanced technologies, such as the laser cooling of atoms and atomic clock, high-precision measurements and spectroscopy, coherent optical communications, and advanced optical sensors. It presents both the fundamentals and characteristics of semiconductor lasers, including basic F-P structure and monolithic integrated structures; interprets laser noises and their measurements; and explains mechanisms and technologies relating to the main aspects of single frequency lasers, including external cavity lasers, frequency stabilization technologies, frequency sweeping, optical phase locked loops, and so on. It paints a clear, physical picture of related technologies and reviews new developments in the field as well. It will be a useful reference to graduate students, researchers, and engineers in the field.

  20. Researcher / Researched: Repositioning Research Paradigms

    Science.gov (United States)

    Meerwald, Agnes May Lin

    2013-01-01

    "Researcher / Researched" calls for a complementary research methodology by proposing autoethnography as both a method and text that crosses the boundaries of conventional and alternative methodologies in higher education. Autoethnography rearticulates the researcher / researched positions by blurring the boundary between them. This…

  1. Time relative single-photon (photoelectron) method

    International Nuclear Information System (INIS)

    Luo Binqiao

    1988-01-01

    A single-photon (photoelectron) measuring system is designed. It researches various problems in single-photon (photoelectron) method. The electronic resolving time is less than 25 ps. The resolving time of single-photon (photoelectron) measuring system is 25 to 65 ps

  2. The Promise of Single-Sex Classes

    Science.gov (United States)

    Stotsky, Sandra

    2012-01-01

    Despite the enthusiasm and the absence of definitive research on the pros and cons of single-sex classes, a 2011 article in Science, titled "The Pseudoscience of Single-Sex Schooling," by a new organization called American Council for CoEducational Schooling (ACCES) came out with the astonishing conclusion that single-sex education is…

  3. Evaluating the quality of research into a single prognostic biomarker: a systematic review and meta-analysis of 83 studies of C-reactive protein in stable coronary artery disease.

    Directory of Open Access Journals (Sweden)

    Harry Hemingway

    2010-06-01

    Full Text Available Systematic evaluations of the quality of research on a single prognostic biomarker are rare. We sought to evaluate the quality of prognostic research evidence for the association of C-reactive protein (CRP with fatal and nonfatal events among patients with stable coronary disease.We searched MEDLINE (1966 to 2009 and EMBASE (1980 to 2009 and selected prospective studies of patients with stable coronary disease, reporting a relative risk for the association of CRP with death and nonfatal cardiovascular events. We included 83 studies, reporting 61,684 patients and 6,485 outcome events. No study reported a prespecified statistical analysis protocol; only two studies reported the time elapsed (in months or years between initial presentation of symptomatic coronary disease and inclusion in the study. Studies reported a median of seven items (of 17 from the REMARK reporting guidelines, with no evidence of change over time. The pooled relative risk for the top versus bottom third of CRP distribution was 1.97 (95% confidence interval [CI] 1.78-2.17, with substantial heterogeneity (I(2 = 79.5. Only 13 studies adjusted for conventional risk factors (age, sex, smoking, obesity, diabetes, and low-density lipoprotein [LDL] cholesterol and these had a relative risk of 1.65 (95% CI 1.39-1.96, I(2 = 33.7. Studies reported ten different ways of comparing CRP values, with weaker relative risks for those based on continuous measures. Adjusting for publication bias (for which there was strong evidence, Egger's p<0.001 using a validated method reduced the relative risk to 1.19 (95% CI 1.13-1.25. Only two studies reported a measure of discrimination (c-statistic. In 20 studies the detection rate for subsequent events could be calculated and was 31% for a 10% false positive rate, and the calculated pooled c-statistic was 0.61 (0.57-0.66.Multiple types of reporting bias, and publication bias, make the magnitude of any independent association between CRP and prognosis

  4. Hydrodynamics and heat transfer in reactor components cooled by liquid metal coolants in single/two phase. 11. meeting of the International Association for Hydraulic Research (IAHR) Working Group. Working material

    International Nuclear Information System (INIS)

    2005-01-01

    This Working Material includes the papers presented at the International Meeting 'Hydrodynamics and heat transfer in reactor components cooled by liquid metal coolants in single/two-phase', which was held 5-9 July 2004 at the State Scientific Center of Russian Federation - Institute for Physics and Power Engineering named after A.I. Leypunsky, in Obninsk near Moscow. The objectives of the meeting were to discuss new results obtained in the field of liquid metal coolant and to recommend the lines of further general physics and applied investigations, with the purpose of validating existing and codes under development for liquid metal cooled advanced and new generation nuclear reactors. Most of the contributions present results of experimental and numerical investigations into velocity, temperature and heat transfer in fuel subassemblies of fast reactors cooled by sodium or lead. In the frame of the meeting a benchmark problem devoted to heat transfer in the model subassembly of the fast reactor BREST-OD-300 was proposed. Experts from 5 countries (Japan, Netherlands, Spain, Republic of Korea, and Russia) took part in this benchmark exercise. The results of the benchmark calculations are summarized in the Working Material. The results of hydrodynamic studies of pressure head chambers and collector systems of liquid metal cooled reactors are presented in a number of papers. Also attention was given to the generalization of experimental data on hydraulic losses in the pipelines in case of mutual influence of local pressure drops, and to the modeling of natural convection in the fuel subassemblies and circuits with liquid metal cooling. Special emphasis at the meeting was placed on thermal hydraulics issues related to the development and design of target systems, such as heat removal in the target unit of the cascade subcritical reactor cooled by liquid salt; the target complex MK-1 for accelerator driven systems cooled by eutectic lead-bismuth alloy; and the test

  5. Microfluidics for single cell analysis

    DEFF Research Database (Denmark)

    Jensen, Marie Pødenphant

    Isolation and manipulation of single cells have gained an increasing interest from researchers because of the heterogeneity of cells from the same cell culture. Single cell analysis can ensure a better understanding of differences between individual cells and potentially solve a variety of clinical...... problems. In this thesis lab on a chip systems for rare single cell analysis are investigated. The focus was to develop a commercial, disposable device for circulating tumour cell (CTC) analysis. Such a device must be able to separate rare cells from blood samples and subsequently capture the specific...... cells, and simultaneously be fabricated and operated at low costs and be user-friendly. These challenges were addressed through development of two microfluidic devices, one for rare cell isolation based on pinched flow fractionation (PFF) and one for single cell capture based on hydrodynamic trapping...

  6. Single-Pilot Workload Management

    Science.gov (United States)

    Rogers, Jason; Williams, Kevin; Hackworth, Carla; Burian, Barbara; Pruchnicki, Shawn; Christopher, Bonny; Drechsler, Gena; Silverman, Evan; Runnels, Barry; Mead, Andy

    2013-01-01

    Integrated glass cockpit systems place a heavy cognitive load on pilots (Burian Dismukes, 2007). Researchers from the NASA Ames Flight Cognition Lab and the FAA Flight Deck Human Factors Lab examined task and workload management by single pilots. This poster describes pilot performance regarding programming a reroute while at cruise and meeting a waypoint crossing restriction on the initial descent.

  7. Use of an in-field-of-view shield to improve count rate performance of the single crystal layer high-resolution research tomograph PET scanner for small animal brain scans

    International Nuclear Information System (INIS)

    Boellaard, R; Jong, H W A M de; Molthoff, C F M; Buijs, F; Lenox, M; Nutt, R; Lammertsma, A A

    2003-01-01

    The count rate performance of the single LSO crystal layer high-resolution research tomograph (HRRT-S) PET scanner is limited by the processing speed of its electronics. Therefore, the feasibility of using an in-field-of-view (in-FOV) shield to improve the noise equivalent count rates (NECR) for small animal brain studies was investigated. The in-FOV shield consists of a lead tube of 12 cm length, 6 cm inner diameter and 9 mm wall thickness. It is large enough to shield the activity in the body of a rat or mouse. First, the effect of this shield on NECR was studied. Secondly, a number of experiments were performed to assess the effects of the shield on the accuracy of transmission scan data and, next, on reconstructed activity distribution in the brain. For activities below 150 MBq NECR improved only by 5-10%. For higher activities NECR maxima of 1.2E4 cps at 200 MBq and 2.2E4 cps at 370 MBq were found without and with shield, respectively. Listmode data taken without shield, however, were corrupted for activities above 75 MBq due to data overrun problems (time tag losses) of the electronics. When the shield was used data overrun was avoided up to activities of 150 MBq. For the unshielded part of the phantom, transmission scan data were the same with and without shield. The estimated scatter contribution was approximately 8.5% without and 5.5% with shield. Reconstructed emission data showed a difference up to 5% in the unshielded part of the phantom at 5 mm or more from the edge of the shielding. Of this 5% about 3% results from the difference in the uncorrected scatter contribution. In conclusion, an in-FOV shield can be used successfully in an HRRT PET scanner to improve NECR and accuracy of small animal brain studies. The latter is especially important when high activities are required for tracers with low brain uptake or when multiple animals are scanned simultaneously. (note)

  8. A Study on the IAEA Technical Exhibition on the Technology related to Research Reactor in Korea

    International Nuclear Information System (INIS)

    Wu, S. I.; Oh, S. Y.; Ha, J. J.

    2011-03-01

    The Republic of Korea is holding an exhibition to share the experience and relevant knowledge on the development of nuclear infrastructure including Research Reactor exportation with the IAEA Member States. It is on display at Booth No. 7-9, Ground Floor of Building C, VIC Rotunda for one week from 20 to 24 September 2010. The exhibition, under the theme 'Research reactor and it's Technology in Korea', puts emphasis on Korea's experience and knowledge accumulated in the course of implementing nuclear power projects particularly in the development of nuclear infrastructure including Research Reactor exportation through the past half century. The experience and knowledge could serve as an invaluable model to the IAEA Member States that are interested in nuclear power projects. This project covers development of display material for the exhibition as follows; o Development of 6 minute video images titled 'Research reactor and it's Technology in Korea' to be presented for the exhibition. o Development of panels titled 'Jordan Research and Training Reactor', and 'Advanced Korean Research Reactor Technology using HANARO' o Selection of display materials, i.e., JRTR mock-up which is miniature of JRTR designed by the KAERI, guidance of JRTR project(including size, thermal power and so on) o Publication of exhibition brochure which explains the development of Korea's nuclear energy and closer cooperation between Korea and the IAEA. o Publication of the exhibition invitation card

  9. The most important single factor influencing learning is what the learner already knows - What do the learner know about clouds, precipitation, wind and greenhouse effect; a short review of research from 1883 to 2009

    Science.gov (United States)

    Hansen, P. J. K.

    2009-09-01

    If I had to reduce all of educational psychology to just one principle, I would say this: The most important single factor influencing learning is what the learner already knows. Ascertain this and teach him accordingly. This famous quotation from David Ausubel in 1968 points out one of the fundaments for constructivism as theory of learning and knowledge, and states a still common held teaching approach. The first one found to investigate "what the learner already knows" about weather and climate elements, was the American pioneer psychologist Granville Stanley Hall in 1883, studying children of age 4 to 8. Since then many articles and books have been written on the same topics under different theories of learning, knowledge and teaching. Most outstanding are two books from Jean Piaget in 1926 and 1927, both including children's shifting ideas from age 3 to 12 about weather and climate elements and their causes. His books were the start of his lifelong work (till 1980) on what he called theory of Genetic Epistemology, another fundament of constructivism. Common features of Hall, Piaget and many other researches' discoveries are for instance that the youngest children (smoke, dust, earth or stone. Clouds move because men, God or the clouds themselves want to; or move when we move. Clouds give rain because men, God or the clouds themselves want to; or rain is needed; or the clouds sweat or melt; or rain is sinks or buckets in the clouds running over. Wind is the breath of men or God; or made by machines; or made by the movement of trees, clouds or other objects. The presentation will discuss some ideas of how to "teach him accordingly" at primary and lower secondary education. The first one found to investigate what the learner already knows about the greenhouse effect and related topics is this author in 1989, studying students at age 15. The most outstanding and productive researchers on this field are the English environmental educators Edward Boyes and Martin

  10. Single Audit: Single Audit Act Effectiveness Issues

    National Research Council Canada - National Science Library

    Thompson, Sally

    2002-01-01

    As discussed in the report we are releasing today, our work to review agency actions to ensure that recipients take timely and appropriate corrective actions to fix audit findings contained in single...

  11. Single photon from a single trapped atom

    International Nuclear Information System (INIS)

    Dingjan, J.; Jones, M.P.A.; Beugnon, J.; Darquiee, B.; Bergamini, S.; Browaeys, A.; Messin, G.; Grangier, P.

    2005-01-01

    Full text: A quantum treatment of the interaction between atoms and light usually begins with the simplest model system: a two-level atom interacting with a monochromatic light wave. Here we demonstrate an elegant experimental realization of this system using an optically trapped single rubidium atom illuminated by resonant light pulses. We observe Rabi oscillations, and show that this system can be used as a highly efficient triggered source of single photons with a well-defined polarisation. In contrast to other sources based on neutral atoms and trapped ions, no optical cavity is required. We achieved a flux of single photons of about 10 4 s -1 at the detector, and observe complete antibunching. This source has potential applications for distributed atom-atom entanglement using single photons. (author)

  12. Single Molecule Applications of Quantum Dots

    DEFF Research Database (Denmark)

    Rasmussen, Thomas Elmelund; Jauffred, Liselotte; Brewer, Jonathan R.

    2013-01-01

    Fluorescent nanocrystals composed of semiconductor materials were first introduced for biological applications in the late 1990s. The focus of this review is to give a brief survey of biological applications of quantum dots (QDs) at the single QD sensitivity level. These are described as follows:...... experiments held together with the prospects in localization microscopy and single molecule manipulation experiments gave QDs a promising future in single molecule research....

  13. Research Associate | Center for Cancer Research

    Science.gov (United States)

    PROGRAM DESCRIPTION The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives.  The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI’s intramural Center for Cancer Research (CCR).  The dedicated units provide electron microscopy, protein characterization, protein expression, optical microscopy and nextGen sequencing. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research.  CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise. KEY ROLES/RESPONSIBILITIES We are seeking a highly motivated Research Associate II to join the newly established Single Cell Analysis Facility (SCAF) of the CCR at NCI.  The SCAF will house state of the art single cell sequencing technologies including 10xGenomics Chromium, BD Genomics Rhapsody, DEPPArray, and other emerging single cell technologies. This person will work under the guidance of SCAF senior staff to carry out single cell sequencing experiments.

  14. Single frequency intracavity SRO

    DEFF Research Database (Denmark)

    Abitan, Haim; Buchhave, Preben

    2000-01-01

    Summary form only given. A single resonance optical parametric oscillator (SRO) is inserted intracavity to a CW high power, single frequency, and ring Nd:YVO4 laser. We obtain a stable single frequency CW SRO with output at 1.7-1.9 μm (idler) and a resonating signal at 2.3-2.6 μm. The behavior...

  15. Single atom spintronics

    International Nuclear Information System (INIS)

    Sullivan, M. R.; Armstrong, J. N.; Hua, S. Z.; Chopra, H. D.

    2005-01-01

    Full text: Single atom spintronics (SASS) represents the ultimate physical limit in device miniaturization. SASS is characterized by ballistic electron transport, and is a fertile ground for exploring new phenomena. In addition to the 'stationary' (field independent) scattering centers that have a small and fixed contribution to total transmission probability of electron waves, domain walls constitute an additional and enhanced source of scattering in these magnetic quantum point contacts (QPCs), the latter being both field and spin-dependent. Through the measurement of complete hysteresis loops as a function of quantized conductance, we present definitive evidence of enhanced backscattering of electron waves by atomically sharp domain walls in QPCs formed between microfabricated thin films [1]. Since domain walls move in a magnetic field, the magnitude of spin-dependent scattering changes as the QPC is cycled along its hysteresis loop. For example, as shown in the inset in Fig. 1, from zero towards saturation in a given field direction, the resistance varies as the wall is being swept away, whereas the resistance is constant upon returning from saturation towards zero, since in this segment of the hysteresis loop no domain wall is present across the contact. The observed spin-valve like behavior is realized by control over wall width and shape anisotropy. This behavior also unmistakably sets itself apart from any mechanical artifacts; additionally, measurements made on single atom contacts provide an artifact-free environment [2]. Intuitively, it is simpler to organize the observed BMR data according to all possible transitions between different conductance plateaus, as shown by the dotted line in Fig. 1; the solid circles show experimental data for Co, which follows the predicted scheme. Requisite elements for the observation of the effect will be discussed in detail along with a review of state of research in this field. Practically, the challenge lies in making

  16. Single Molecule Electronics and Devices

    Science.gov (United States)

    Tsutsui, Makusu; Taniguchi, Masateru

    2012-01-01

    The manufacture of integrated circuits with single-molecule building blocks is a goal of molecular electronics. While research in the past has been limited to bulk experiments on self-assembled monolayers, advances in technology have now enabled us to fabricate single-molecule junctions. This has led to significant progress in understanding electron transport in molecular systems at the single-molecule level and the concomitant emergence of new device concepts. Here, we review recent developments in this field. We summarize the methods currently used to form metal-molecule-metal structures and some single-molecule techniques essential for characterizing molecular junctions such as inelastic electron tunnelling spectroscopy. We then highlight several important achievements, including demonstration of single-molecule diodes, transistors, and switches that make use of electrical, photo, and mechanical stimulation to control the electron transport. We also discuss intriguing issues to be addressed further in the future such as heat and thermoelectric transport in an individual molecule. PMID:22969345

  17. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    The research design used in this study is analytical research design. Moreover, the research approach used in the study was a quantitative approach supplemented or complemented by a qualitative research approach. Subjects of the Study and Sampling Techniques. The study was designed to explore the effect of.

  18. FRAXA Research Foundation

    Science.gov (United States)

    ... when a single gene shuts down. Our children lack one protein vital for normal brain ... Advisory Board. FRAXA has funded over $26,000,000 in research worldwide; hundreds of teams are in their labs ...

  19. The Long Night of Research, Vienna International Centre (VIC), Vienna, Austria, 22 April 2016

    International Nuclear Information System (INIS)

    Jandrić, Zora; Abrahim, Aiman; Kelly, Simon; Cannavan, Andrew

    2016-01-01

    On 22 April the IAEA, along with other VIC-based organizations, took part in the biannual Long Night of Research (Lange Nacht der Forschung); an Austria-wide event coordinated by several Austrian government ministries that aims to spark interest in science and research. This was the seventh year of the Long Night of Research, and the first time the IAEA was involved. The VIC was one of around 250 exhibit locations across the country. The event gave visitors a chance to learn about the variety of nuclear applications in various fields. The Food and Environmental Protection Laboratory (FEPL) exhibition booth focused on testing for food authenticity, posing the question ‘is your food what you think it is?’. Food is an essential part of our daily lives. We need our food to be safe and we want to know what we are eating. Nuclear and related techniques can be used to control food safety and to fight food fraud – the deliberate mislabelling of food products

  20. Single ventricle cardiac defect

    International Nuclear Information System (INIS)

    Eren, B.; Turkmen, N.; Fedakar, R.; Cetin, V.

    2010-01-01

    Single ventricle heart is defined as a rare cardiac abnormality with a single ventricle chamber involving diverse functional and physiological defects. Our case is of a ten month-old baby boy who died shortly after admission to the hospital due to vomiting and diarrhoea. Autopsy findings revealed cyanosis of finger nails and ears. Internal examination revealed; large heart, weighing 60 grams, single ventricle, without a septum and upper membranous part. Single ventricle is a rare pathology, hence, this paper aims to discuss this case from a medico-legal point of view. (author)

  1. Research of predictive factors for cardiac resynchronization therapy: a prospective study comparing data from phase-analysis of gated myocardial perfusion single-photon computed tomography and echocardiography : Trying to anticipate response to CRT.

    Science.gov (United States)

    Gendre, Rémy; Lairez, O; Mondoly, P; Duparc, A; Carrié, D; Galinier, M; Berry, I; Cognet, T

    2017-04-01

    Cardiac resynchronization therapy (CRT) reduces morbidity and mortality in chronic systolic heart failure. About 20% of implanted patients are considered as "non-responders". This study aimed to evaluate gated myocardial perfusion single-photon emission computed tomography (GMPS) phase parameters as compared to echocardiography in the assessment of predictors for response to CRT before and after CRT activation. Forty-two patients were prospectively included during 15 months. A single injection of 99m Tc-tetrofosmin was used to acquire GMPS phase pre- and post-CRT activation. Indicators of positive CRT response were improvement of functional status and 15% reduction in left ventricular end-systolic volume at 3 months. Phase parameters at baseline were similar in the two groups with no influence of perfusion data. Phase parameters after CRT activation were significantly improved in the responders' group (Δ Bandwidth -19° ± 24° vs. 13° ± 31°, p = 0.001; Δ SD -20° ± 30° vs. 26° ± 46°, p = 0.001; Δ Entropy -11 ± 12 vs. 2 ± 6%, p = 0.001). Feasibility and reproducibility were higher for GMPS. Acute phase modifications after CRT activation may predict response to CRT immediately after implantation, but not at baseline, even when adjusted to perfusion data.

  2. Plant single-cell and single-cell-type metabolomics.

    Science.gov (United States)

    Misra, Biswapriya B; Assmann, Sarah M; Chen, Sixue

    2014-10-01

    In conjunction with genomics, transcriptomics, and proteomics, plant metabolomics is providing large data sets that are paving the way towards a comprehensive and holistic understanding of plant growth, development, defense, and productivity. However, dilution effects from organ- and tissue-based sampling of metabolomes have limited our understanding of the intricate regulation of metabolic pathways and networks at the cellular level. Recent advances in metabolomics methodologies, along with the post-genomic expansion of bioinformatics knowledge and functional genomics tools, have allowed the gathering of enriched information on individual cells and single cell types. Here we review progress, current status, opportunities, and challenges presented by single cell-based metabolomics research in plants. Copyright © 2014 Elsevier Ltd. All rights reserved.

  3. Single Cell Isolation and Analysis

    Directory of Open Access Journals (Sweden)

    Ping Hu

    2016-10-01

    Full Text Available Increasing evidence shows that the heterogeneity of individual cells within a genetically identical population can be critical to their peculiar function and fate. Conventional cell based assays mainly analysis the average responses from a population cells, while the difference within individual cells may often be masked. The cell size, RNA transcripts and protein expression level are quite different within individual cells and these variations are key point to answer the problems in cancer, neurobiology, stem cell biology, immunology and developmental biology. To better understand the cell-to-cell variations, the single cell analysis can provide much more detailed information which may be helpful for therapeutic decisions in an increasingly personalized medicine. In this review, we will focus on the recent development in single cell analysis, including methods used in single cell isolation, analysis and some application examples. The review provides the historical background to single cell analysis, discusses limitations, and current and future possibilities in this exciting field of research.

  4. Single-Molecule Spectroscopy

    Indian Academy of Sciences (India)

    IAS Admin

    GENERAL ARTICLE. Single-Molecule Spectroscopy. Every Molecule is Different! Kankan Bhattacharyya. Keywords. Single-molecule spectroscopy. (SMS), confocal microscopy,. FCS, sm-FRET, FLIM. 1 High-resolution spectrum re- fers to a spectrum consisting of very sharp lines. The sharp lines clearly display transitions to ...

  5. Single-Molecule Spectroscopy

    Indian Academy of Sciences (India)

    IAS Admin

    RESONANCE. February 2015. GENERAL ARTICLE. Single-Molecule Spectroscopy. Every Molecule is Different! Kankan Bhattacharyya. Keywords. Single-molecule ..... Resonance Energy. Transfer (FRET) is an elegant technique to measure the distance between a donor and an acceptor molecule. FRET refers to the.

  6. Single photon and nonlocality

    Indian Academy of Sciences (India)

    critical analysis of the concept of hidden variable used by the authors of [1] shows that the reasoning is not correct. Keywords. Nonlocality; single particle; hidden variables. PACS Nos 03.67.Ba; 03.65.Ta; 32.80.Lg; 07.79.Fc. 1. Introduction. Quantum nonlocality [2] for single particle is a subject of debate since the origin.

  7. Single gaze gestures

    DEFF Research Database (Denmark)

    Møllenbach, Emilie; Lilholm, Martin; Gail, Alastair

    2010-01-01

    This paper examines gaze gestures and their applicability as a generic selection method for gaze-only controlled interfaces. The method explored here is the Single Gaze Gesture (SGG), i.e. gestures consisting of a single point-to-point eye movement. Horizontal and vertical, long and short SGGs were...

  8. Understanding Single Adulthood.

    Science.gov (United States)

    Stein, Peter J.

    The life styles and life chances of the unmarried include elements of choices. Singles may be grouped and characterized according to whether their status may be considered stable or temporary. A life cycle, or continuum model of singlehood is reviewed, including its different factors, or phases. A new model for singles is proposed--a life spiral…

  9. Single-sided NMR

    CERN Document Server

    Casanova, Federico; Blümich, Bernhard

    2011-01-01

    Single-Sided NMR describes the design of the first functioning single-sided tomograph, the related measurement methods, and a number of applications. One of the key advantages to this method is the speed at which the images are obtained.

  10. Single Nanoparticle Plasmonic Sensors

    Directory of Open Access Journals (Sweden)

    Manish Sriram

    2015-10-01

    Full Text Available The adoption of plasmonic nanomaterials in optical sensors, coupled with the advances in detection techniques, has opened the way for biosensing with single plasmonic particles. Single nanoparticle sensors offer the potential to analyse biochemical interactions at a single-molecule level, thereby allowing us to capture even more information than ensemble measurements. We introduce the concepts behind single nanoparticle sensing and how the localised surface plasmon resonances of these nanoparticles are dependent upon their materials, shape and size. Then we outline the different synthetic approaches, like citrate reduction, seed-mediated and seedless growth, that enable the synthesis of gold and silver nanospheres, nanorods, nanostars, nanoprisms and other nanostructures with tunable sizes. Further, we go into the aspects related to purification and functionalisation of nanoparticles, prior to the fabrication of sensing surfaces. Finally, the recent developments in single nanoparticle detection, spectroscopy and sensing applications are discussed.

  11. Single-photon imaging

    CERN Document Server

    Seitz, Peter

    2011-01-01

    The acquisition and interpretation of images is a central capability in almost all scientific and technological domains. In particular, the acquisition of electromagnetic radiation, in the form of visible light, UV, infrared, X-ray, etc. is of enormous practical importance. The ultimate sensitivity in electronic imaging is the detection of individual photons. With this book, the first comprehensive review of all aspects of single-photon electronic imaging has been created. Topics include theoretical basics, semiconductor fabrication, single-photon detection principles, imager design and applications of different spectral domains. Today, the solid-state fabrication capabilities for several types of image sensors has advanced to a point, where uncoooled single-photon electronic imaging will soon become a consumer product. This book is giving a specialist´s view from different domains to the forthcoming “single-photon imaging” revolution. The various aspects of single-photon imaging are treated by internati...

  12. A new high-quality set of singly (H-2) and doubly (H-2 and O-18) stable isotope labeled reference waters for biomedical and other isotope-labeled research

    NARCIS (Netherlands)

    Faghihi, V.; Verstappen-Dumoulin, B. M. A. A.; Jansen, H. G.; van Dijk, G.; Aerts-Bijma, A. T.; Kerstel, E. R. T.; Groening, M.; Meijer, H. A. J.

    2015-01-01

    RATIONALE: Research using water with enriched levels of the rare stable isotopes of hydrogen and/or oxygen requires well-characterized enriched reference waters. The International Atomic Energy Agency (IAEA) did have such reference waters available, but these are now exhausted. New reference waters

  13. Original Research Original Research

    African Journals Online (AJOL)

    User

    anically governed fuel e past, the marked uting power on the in the market has made el control to el fuel injection system. To conduct laboratory single cylinder engine, ction variables and the de flexible. As such, an for the system was variables like injection and multiple injection egulated and controlled n advanced injection.

  14. Single Sign-on Authentication server (part of CLARIN infrastructure)

    NARCIS (Netherlands)

    de Jong, H.A.; Maas, M.

    2013-01-01

    The Huygens Single Sign-on server allows federated logins (authentication) via SURFconext affiliates thus facilitating all connected (academic / research) institutes to use online Huygens ING software services.

  15. Single neuron computation

    CERN Document Server

    McKenna, Thomas M; Zornetzer, Steven F

    1992-01-01

    This book contains twenty-two original contributions that provide a comprehensive overview of computational approaches to understanding a single neuron structure. The focus on cellular-level processes is twofold. From a computational neuroscience perspective, a thorough understanding of the information processing performed by single neurons leads to an understanding of circuit- and systems-level activity. From the standpoint of artificial neural networks (ANNs), a single real neuron is as complex an operational unit as an entire ANN, and formalizing the complex computations performed by real n

  16. Single photon ECT

    International Nuclear Information System (INIS)

    Maeda, Toshio; Matsuda, Hiroshi; Tada, Akira; Bunko, Hisashi; Koizumi, Kiyoshi

    1982-01-01

    The detectability of lesions located deep in a body or overlapped with a physiologically increased activity improve with the help of single photon ECT. In some cases, the ECT is superior to the conventional gamma camera images and X-ray CT scans in the evaluation of the location and size of lesion. The single photon ECT of the brain compares favorably with the contrast enhansed X-ray CT scans. The most important adaptation of the single photon ECT are the detection of recurrent brain tumors after craniotomy and the evaluation of ischemic heart diseases. (author)

  17. Single Electron Tunneling

    International Nuclear Information System (INIS)

    Ruggiero, Steven T.

    2005-01-01

    Financial support for this project has led to advances in the science of single-electron phenomena. Our group reported the first observation of the so-called ''Coulomb Staircase'', which was produced by tunneling into ultra-small metal particles. This work showed well-defined tunneling voltage steps of width e/C and height e/RC, demonstrating tunneling quantized on the single-electron level. This work was published in a now well-cited Physical Review Letter. Single-electron physics is now a major sub-field of condensed-matter physics, and fundamental work in the area continues to be conducted by tunneling in ultra-small metal particles. In addition, there are now single-electron transistors that add a controlling gate to modulate the charge on ultra-small photolithographically defined capacitive elements. Single-electron transistors are now at the heart of at least one experimental quantum-computer element, and single-electron transistor pumps may soon be used to define fundamental quantities such as the farad (capacitance) and the ampere (current). Novel computer technology based on single-electron quantum dots is also being developed. In related work, our group played the leading role in the explanation of experimental results observed during the initial phases of tunneling experiments with the high-temperature superconductors. When so-called ''multiple-gap'' tunneling was reported, the phenomenon was correctly identified by our group as single-electron tunneling in small grains in the material. The main focus throughout this project has been to explore single electron phenomena both in traditional tunneling formats of the type metal/insulator/particles/insulator/metal and using scanning tunneling microscopy to probe few-particle systems. This has been done under varying conditions of temperature, applied magnetic field, and with different materials systems. These have included metals, semi-metals, and superconductors. Amongst a number of results, we have

  18. Thermal and Pressure Characterization of a Wind Tunnel Force Balance Using the Single Vector System. Experimental Design and Analysis Approach to Model Pressure and Temperature Effects in Hypersonic Wind Tunnel Research

    Science.gov (United States)

    Lynn, Keith C.; Commo, Sean A.; Johnson, Thomas H.; Parker, Peter A,

    2011-01-01

    Wind tunnel research at NASA Langley Research Center s 31-inch Mach 10 hypersonic facility utilized a 5-component force balance, which provided a pressurized flow-thru capability to the test article. The goal of the research was to determine the interaction effects between the free-stream flow and the exit flow from the reaction control system on the Mars Science Laboratory aeroshell during planetary entry. In the wind tunnel, the balance was exposed to aerodynamic forces and moments, steady-state and transient thermal gradients, and various internal balance cavity pressures. Historically, these effects on force measurement accuracy have not been fully characterized due to limitations in the calibration apparatus. A statistically designed experiment was developed to adequately characterize the behavior of the balance over the expected wind tunnel operating ranges (forces/moments, temperatures, and pressures). The experimental design was based on a Taylor-series expansion in the seven factors for the mathematical models. Model inversion was required to calculate the aerodynamic forces and moments as a function of the strain-gage readings. Details regarding transducer on-board compensation techniques, experimental design development, mathematical modeling, and wind tunnel data reduction are included in this paper.

  19. Stresses of Single Parenting

    Science.gov (United States)

    ... Text Size Email Print Share Stresses of Single Parenting Page Content Article Body What are some ways ... way. Check your local library for books on parenting. Local hospitals, the YMCA, and church groups often ...

  20. A Single Atom Antenna

    International Nuclear Information System (INIS)

    Trinter, Florian; Williams, Joshua B; Weller, Miriam; Waitz, Markus; Pitzer, Martin; Voigtsberger, Jörg; Schober, Carl; Kastirke, Gregor; Müller, Christian; Goihl, Christoph; Burzynski, Phillip; Wiegandt, Florian; Wallauer, Robert; Kalinin, Anton; Schmidt, Lothar Ph H; Schöffler, Markus S; Jahnke, Till; Dörner, Reinhard; Chiang, Ying-Chih; Gokhberg, Kirill

    2015-01-01

    Here we demonstrate the smallest possible implementation of an antenna-receiver complex which consists of a single (helium) atom acting as the antenna and a second (neon) atom acting as a receiver. (paper)

  1. Single Beam Holography.

    Science.gov (United States)

    Chen, Hsuan; Ruterbusch, Paul H.

    1979-01-01

    Discusses how holography can be used as part of undergraduate physics laboratories. The authors propose a single beam technique of holography, which will reduce the recording scheme as well as relax the isolation requirements. (HM)

  2. Epigenetics reloaded: the single-cell revolution.

    Science.gov (United States)

    Bheda, Poonam; Schneider, Robert

    2014-11-01

    Mechanistically, how epigenetic states are inherited through cellular divisions remains an important open question in the chromatin field and beyond. Defining the heritability of epigenetic states and the underlying chromatin-based mechanisms within a population of cells is complicated due to cell heterogeneity combined with varying levels of stability of these states; thus, efforts must be focused toward single-cell analyses. The approaches presented here constitute the forefront of epigenetics research at the single-cell level using classic and innovative methods to dissect epigenetics mechanisms from the limited material available in a single cell. This review further outlines exciting future avenues of research to address the significance of epigenetic heterogeneity and the contributions of microfluidics technologies to single-cell isolation and analysis. Copyright © 2014 Elsevier Ltd. All rights reserved.

  3. Single-cell photoacoustic thermometry.

    Science.gov (United States)

    Gao, Liang; Wang, Lidai; Li, Chiye; Liu, Yan; Ke, Haixin; Zhang, Chi; Wang, Lihong V

    2013-02-01

    A novel photoacoustic thermometric method is presented for simultaneously imaging cells and sensing their temperature. With three-seconds-per-frame imaging speed, a temperature resolution of 0.2°C was achieved in a photo-thermal cell heating experiment. Compared to other approaches, the photoacoustic thermometric method has the advantage of not requiring custom-developed temperature-sensitive biosensors. This feature should facilitate the conversion of single-cell thermometry into a routine lab tool and make it accessible to a much broader biological research community.

  4. Upconversion luminescence behavior of single nanoparticles

    Science.gov (United States)

    Zhou, Jiajia; Xu, Shiqing; Zhang, Junjie; Qiu, Jianrong

    2015-09-01

    Upconversion nanoparticles (UCNPs) have made a significant and valuable contribution to materials science, photophysics, and biomedicine due to their specific spectroscopic characteristics. However, the ensemble spectroscopy of UCNPs is limited because of the electronic behavior in average effect, which ignores the fact that these nanoparticles are heterogeneous. With regards to the research focus on heterogeneous intrinsic structures, unique photophysical phenomena, and advanced applications, the optical characterization of single UCNPs have been promoted to the frontier development of the UCNPs community. In this review, we give an overview of the importance of single UCNPs characterization, typical principles of UC, and single particle detection methods. Considerable emphasis is placed on the specific spectroscopic study of single UCNPs, which shows fantastic photophysical phenomena beyond ensemble measurement. Parallel efforts are devoted to the current applications of single UCNPs.

  5. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    rts Research Journal. 2015, 4(4): 58-64. ://www.starjournal.org/ ts of Some Species stern Ghats. 577 451, vempu University,. Article Information. Article History: ..... Journal of. Medicinal Plants Research 4(3): 267-270. Johns, T., Duquette, M. (1991). Deficiency of phosphorus in man. The American Journal of Clinical Nutrition ...

  6. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    ere analyzed by descriptive statistics, Pearson Product nd factor analysis. Findings showed that 64.3percent of in Ise Ekiti. The mean score of the respondent's age was re married with ... n, storage of watermelon, market price of watermelon and elon disease .... research objectives and research works related to the issues.

  7. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    Faculty of Education and Behavioral Science,. Abstract. The main purpose of this research was to examine th styles, academic self concept, academic motivation and s sample for this research consisted of 136 from stratified random sampling of which 82 males and 54 students consisting grade 9th and 10th. Data analysis w.

  8. Elementary Student Perspectives on Single-Gender Classes

    Science.gov (United States)

    Tichenor, Mercedes; Tichenor, John; Piechura, Kathy; Heins, Elizabeth; MacIssac, Doug

    2015-01-01

    Interest in single-gender education has grown significantly since the U.S. Department of Education published regulations for the practice in 2006. Although research provides mixed results on the academic effectiveness of single-gender programs, many districts around the country are providing single-gender classes as a parent choice option under…

  9. The Feasibility of Single-Item Measures for Organizational Justice

    Science.gov (United States)

    Jordan, Jeremy S.; Turner, Brian A.

    2008-01-01

    Researchers in a number of disciplines have examined the utility of single-item measures for both affective and cognitive constructs. While these authors have indicated that, under certain circumstances, the use of single-item measures is appropriate, there remains concern regarding the reliability and validity of single-item measures. This study…

  10. Single fatherhood due to cancer.

    Science.gov (United States)

    Yopp, Justin M; Rosenstein, Donald L

    2012-12-01

    Cancer is a leading cause of widowed fatherhood in the USA. Fathers whose spouses have died from cancer constitute a potentially vulnerable population as they adjust to their role as sole or primary caregiver while managing their own grief and that of their children. The importance of addressing the psychological needs of widowed fathers is underscored by data showing that father's coping and emotional availability are closely tied to their bereaved children's mental health. Surprisingly, scant attention has been given to the phenomenon of widowed fatherhood with virtually no clinical resources or research studies devoted to fathers who have lost their wives to cancer. This commentary highlights key challenges facing this underserved population of widowers and calls for development of research agendas and clinical interventions for single fathers due to cancer. Copyright © 2011 John Wiley & Sons, Ltd.

  11. Single-pilot workload management in entry-level jets.

    Science.gov (United States)

    2013-09-01

    Researchers from the NASA Ames Flight Cognition Lab and the FAAs Flight Deck Human Factors Research Laboratory at the Civil Aerospace Medical Institute (CAMI) examined task and workload management by single pilots in Very Light Jets (VLJs), also c...

  12. Single-Mode VCSELs

    Science.gov (United States)

    Larsson, Anders; Gustavsson, Johan S.

    The only active transverse mode in a truly single-mode VCSEL is the fundamental mode with a near Gaussian field distribution. A single-mode VCSEL produces a light beam of higher spectral purity, higher degree of coherence and lower divergence than a multimode VCSEL and the beam can be more precisely shaped and focused to a smaller spot. Such beam properties are required in many applications. In this chapter, after discussing applications of single-mode VCSELs, we introduce the basics of fields and modes in VCSELs and review designs implemented for single-mode emission from VCSELs in different materials and at different wavelengths. This includes VCSELs that are inherently single-mode as well as inherently multimode VCSELs where higher-order modes are suppressed by mode selective gain or loss. In each case we present the current state-of-the-art and discuss pros and cons. At the end, a specific example with experimental results is provided and, as a summary, the most promising designs based on current technologies are identified.

  13. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    . This study focused on assessing the perceptions, prac instruction by primary school teachers. The research type with embedded mixed approach. Data were ga primary school teachers via questionnaire, semi discussion. The reliability ...

  14. Single-Photon Optomechanics

    Science.gov (United States)

    Nunnenkamp, A.; Børkje, K.; Girvin, S. M.

    2011-08-01

    Optomechanics experiments are rapidly approaching the regime where the radiation pressure of a single photon displaces the mechanical oscillator by more than its zero-point uncertainty. We show that in this limit the power spectrum has multiple sidebands and that the cavity response has several resonances in the resolved-sideband limit. Using master-equation simulations, we also study the crossover from the weak-coupling many-photon to the single-photon strong-coupling regime. Finally, we find non-Gaussian steady states of the mechanical oscillator when multiphoton transitions are resonant. Our study provides the tools to detect and take advantage of this novel regime of optomechanics.

  15. Single well techniques

    International Nuclear Information System (INIS)

    Drost, W.

    1983-01-01

    The single well technique method includes measurement of parameters of groundwater flow in saturated rock. For determination of filtration velocity the dilution of radioactive tracer is measured, for direction logging the collimeter is rotated in the probe linked with the compass. The limiting factor for measurement of high filtration velocities is the occurrence of turbulent flow. The single well technique is used in civil engineering projects, water works and subsurface drainage of liquid waste from disposal sites. The radioactive tracer method for logging the vertical fluid movement in bore-holes is broadly used in groundwater survey and exploitation. (author)

  16. Biocatalytic Single Enzyme Nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Grate, Jay W.; Kim, Jungbae

    2004-03-31

    As an innovative way of enzyme stabilization, we recently developed a new enzyme composite of nano-meter scale that we call "single-enzyme nanoparticles (SENs)" (9). Each enzyme molecule is surrounded with a porous composite organic/inorganic network of less than a few nanometers think. This approach represents a new type of enzyme-containing nanostructure. In experiments with perotease (chymotrypsin, CT), the activity of single enzyme nanoparticle form of the enzyme was greatly stabilized compared to the free form, without imposing a serious mass transfer limitation of substrates. In this chapter we will describe the synthesis, characterization and catalytic activity of the new SENs.

  17. Single port laparoscopic surgery

    DEFF Research Database (Denmark)

    Springborg, Henrik; Istre, Olav

    2012-01-01

    potential benefits. Theoretically, cosmetic outcomes, postoperative pain and complication rates could be improved with use of single site surgery. This study describes introduction of the method in a private hospital in Denmark, in which 40 patients have been treated for benign gynecologic conditions......LESS, or laparo-endoscopic single site surgery, is a promising new method in minimally invasive surgery. An increasing number of surgical procedures are being performed using this technique, however, its large-scale adoption awaits results of prospective randomized controlled studies confirming...

  18. Single-Sex Education in Public School Settings

    Science.gov (United States)

    Crawford-Ferre, Heather Glynn; Wiest, Lynda R.

    2013-01-01

    Although researchers have studied the effectiveness of single-sex education (SSE), the findings have been mixed. This exploratory study reports the perceived goals and effectiveness of single-sex education based on interviews with a small group of educators involved with SSE in various ways. Research participants included a school principal and…

  19. Gender and Leadership Styles in Single-Sex Academic Institutions

    Science.gov (United States)

    Taleb, Hanan M.

    2010-01-01

    Purpose: This paper aims to investigate the relationship between gender and female leadership styles in a single-sex academic institution in Saudi Arabia. Design/methodology/approach: Essentially, a qualitative research approach that utilised a single case-study methodology was adopted. As part of this research, seven in-depth semi-structured…

  20. Artistic research, context research

    Directory of Open Access Journals (Sweden)

    Ricardo Benjamín Toledo Castellanos

    2012-06-01

    Full Text Available Some concepts in contemporary art works, dealing with some life aspects and passed through the sensitive and expressive test, are formulated in this paper and shed light on the foundation of researches about singular phenomenons of the existence. For this, it is argued that there are researches belonging to arts, fundamental researches that compromise the certainty of the assumptions where the sense system of a context has its bases (epoch, culture, nation, region. These researches come ahead of the researches of the rational-discursive enunciation fields, given that the last ones haven’t passed any protocol accepted yet by any community. To bring into play the certainty is done by a cognitive movement named by Martin Heidegger unconcealment [Unverborgenheit], and it consist on the interruption of the habituality of the beings who form the (trustworthy family setting to put into perspective the fundamental structures that allow to produce its sense. The unconcealment, typical in art and in creative actions, sets up an event that stops the solidity of the established (social, ethical, technical, scientific, philosophical order, and unleashes conditions for changing the lifestyles hold until then.

  1. Single-Molecule Spectroscopy

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 20; Issue 2. Single-Molecule Spectroscopy: Every Molecule is Different! Kankan Bhattacharyya. General Article Volume 20 Issue 2 February 2015 pp 151-164. Fulltext. Click here to view fulltext PDF. Permanent link:

  2. Single Nucleotide Polymorphism

    DEFF Research Database (Denmark)

    Børsting, Claus; Pereira, Vania; Andersen, Jeppe Dyrberg

    2014-01-01

    Single nucleotide polymorphisms (SNPs) are the most frequent DNA sequence variations in the genome. They have been studied extensively in the last decade with various purposes in mind. In this chapter, we will discuss the advantages and disadvantages of using SNPs for human identification...

  3. Single Value Devices

    NARCIS (Netherlands)

    Mader, Angelika H.; Dertien, Edwin Christian; Reidsma, Dennis

    2011-01-01

    We live in a world of continuous information overflow, but the quality of information and communication is suffering. Single value devices contribute to the information and communication quality by fo- cussing on one explicit, relevant piece of information. The information is decoupled from a

  4. Single Value Devices

    NARCIS (Netherlands)

    Mader, Angelika H.; Dertien, Edwin Christian; Reidsma, Dennis; Camurri, Antonio; Costa, Cristina

    We live in a world of continuous information overflow, but the quality of information and communication is suffering. Single value devices contribute to information and communication quality by focussing on one explicit, relevant piece of information. The information is decoupled from a computer and

  5. Single Value Devices

    NARCIS (Netherlands)

    Mader, Angelika H.; Reidsma, Dennis; Dertien, Edwin Christian; Volpe, G; Kolkmeier, Jan; Camurri, A.; Kolkmeier, Jan; Nijholt, Antinus

    2015-01-01

    We live in a world of continuous information overflow, but the quality of information and communication is suffering. Single value devices contribute to the information and communication quality by focussing on one explicit, relevant piece of information. The information is decoupled from a computer

  6. Beware the single hit!

    CERN Multimedia

    2008-01-01

    The first time that single particle effects from cosmic rays on electronics were observed was in 1991, when one of the instruments aboard an ESA satellite broke down after only five days in space. On 5 July, the TS-LEA group will have completed the installation of monitors that will help to reduce similar dangerous effects on LHC electronics.

  7. Single reusable spacecraft

    Data.gov (United States)

    National Aeronautics and Space Administration — Design of a my single person reusable spacecraft. It can carry one person and it has to be dropped from an aircraft at an altitude of 40,000 - 45,000 feet. Can be...

  8. Single-Molecule Spectroscopy

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 20; Issue 2. Single-Molecule Spectroscopy: Every Molecule is Different! ... Author Affiliations. Kankan Bhattacharyya1. Department of Physical Chemistry, Indian Association for the Cultivation of Science Jadavpur, Kolkata 700 032 India.

  9. Single photon and nonlocality

    Indian Academy of Sciences (India)

    In a paper by Home and Agarwal [1], it is claimed that quantum nonlocality can be revealed in a simple interferometry experiment using only single particles. A critical analysis of the concept of hidden variable used by the authors of [1] shows that the reasoning is not correct.

  10. Beyond the Single Story

    Science.gov (United States)

    McKenney, Yekaterina

    2016-01-01

    Teachers of world literature have the opportunity to help students explore the more complex reality behind the stereotypes that they often see in the media. If we don't encourage students to challenge one-dimensional "single stories" that characterize an entire people--whether Muslims, Russians, Mexicans, African Americans, Chinese,…

  11. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    Science, T. Sci. Technol. Study on Silkworm Bed Cleaning. Abiy Tilahun*, Kedir Shifa, Ah. Ethiopian Institute of Agricultural Research, M. Abstract. Bed cleaning is an important ... DOI: http://dx.doi.org/10.4314/star.v4. ISSN: 2226-7522(Print) and .... to them and invariably a part of the feed is left behind on the rearing bed.

  12. Original Research Original Research

    African Journals Online (AJOL)

    User

    2013-03-28

    Mar 28, 2013 ... food production in sub-Saharan Africa coun. (Sanchez, 2010). Soil is the most precious vital natural resource and it must be mana. Original Research .... Exchangeable K and Na were measured by fl photometer. Exchangeable acidity determined by saturating the samples with. KCl solution and titrated with ...

  13. Original Research Original Research

    African Journals Online (AJOL)

    User

    questionnaires and analyzed using cross tab revealed the transfer of ... informal enterprises with the rural economy. Original Research. 95 ... ise from the formal sectors ew (1994) accepts these is study of the dynamics of lared the informal tailoring inputs from intermediary of and this is economic of inputs. According to.

  14. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    rRNA was amplified in MJ Research PTC-225 Peltier. Thermal Cycler. The 27F primer with the sequence. (AGAGTTTGATCMTGGCTCAG) having 20 bases and primer. 1492R with the sequence. (TACGGYTACCTTGTTACGACTT) having 22 bases was used.1ng of template DNA was added to 20 ng of PCR reaction solution.

  15. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    ISSN: 2226-7522(Print) and 2305-. Science, Technology and Arts Research Journ. Sci. Technol. Arts Res. .... did a study on early grade reading and writing. Accordingly, although students in grades 1-3 have been ..... on reading comprehension, vocabulary and grammar sections were developed from chapters covered. In.

  16. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    When the quantitative method was a dominant approach to address the research problem, the qualitative one was used to substantiate the quantitative data. In this study which was conducted at Bahir Dar. University, subjects of the study included 445 the summer modality secondary education prospective teachers of 10.

  17. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    Thirty Grade 4 experimental pre- and post-test research design to ing strategies and fluency as a result of teacher cy tests, two structured classroom observation sed as data collecting instruments. The quantitative and percentages whereas the qualitative ones were ative and qualitative data indicated improvements in use.

  18. Original Research Original Research

    African Journals Online (AJOL)

    User

    2013-05-22

    May 22, 2013 ... and low levels of irrigation, soil degradation, soil erosion, inadequate agricultural research and extension, and constraints in market development. (Alemayehu ..... farm's primary asset. Printed in Australia by BPA Print. Group. Pp. 191. Hazelton Pam and Brian Murphy. (2007). Interpreting Soil. Test Results.

  19. Original Research Original Research

    African Journals Online (AJOL)

    User

    2013-06-20

    Jun 20, 2013 ... great value in Ethiopian socio-economic growt requires small capital, promote inter linkages as it is a base for medium and large enterprises, increased domestic saving investment. Also they help for bal development provision of goods and services. Original Research. 123. 3327 (Online) esearch Journal.

  20. Original Research Original Research

    African Journals Online (AJOL)

    User

    , fatty makeup of compost and raised the tempera of composting dairy manure and bedding by average of 3.4°C during an 8-wk developm period. BD compost preparation are used to. Original Research. 32. 3327 (Online) esearch Journal.

  1. Original Research Original Research

    African Journals Online (AJOL)

    User

    2013-06-25

    Jun 25, 2013 ... the feeding practices (Kassahun, 2000). This involves the use of fodder bank, f trees, agro-industrial by-products such as, seed cake and urea to overcome CP shor. (ILCA, 1990). Supplementation of poor q roughage feed with suitable energy and p. Original Research. 38. 3327 (Online) esearch Journal.

  2. Original Research Original Research

    African Journals Online (AJOL)

    User

    2013-03-30

    Mar 30, 2013 ... cience, Technology and Arts Research. Jan-Mar 2013, .... manner. The 1958/9 curriculum marks the second development in English language education. The third English curriculum appeared in 1963-4. The 1967-8 curriculum is the last ... The students continued using it as a. Medium of Instruction from ...

  3. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    antioxidant activity of the stem bark extract was studied assay. Extract was shown to display a dose dependent f ... play an essential role in the primary health care of 80% the world's underdeveloped and developing countri ... Science, Technology and Arts Research Journ. Sci. Technol. Arts Res. J., April-June 2015, 4.

  4. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    Abstract. This study examined the effects of teacher scaff comprehension in Dona Berber Primary School, Ethiopi were selected using purposive sampling. A quasi research design was employed to examine chang strategies and reading comprehension as a pre-and post-reading comprehension tests checklists, and Focus ...

  5. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    Ethiopian Institute of Agricultural Research, Kulu. Abstract. There is high wheat yield variation among smallholders in mainly due to socio-economic, farm inputs utiliza characteristics of the farmers. This study identifies the probability of wheat yield tends to be relatively low, med influencing factors. Cross-sectional data ...

  6. Experimental techniques for single cell and single molecule biomechanics

    International Nuclear Information System (INIS)

    Lim, C.T.; Zhou, E.H.; Li, A.; Vedula, S.R.K.; Fu, H.X.

    2006-01-01

    Stresses and strains that act on the human body can arise either from external physical forces or internal physiological environmental conditions. These biophysical interactions can occur not only at the musculoskeletal but also cellular and molecular levels and can determine the health and function of the human body. Here, we seek to investigate the structure-property-function relationship of cells and biomolecules so as to understand their important physiological functions as well as establish possible connections to human diseases. With the recent advancements in cell and molecular biology, biophysics and nanotechnology, several innovative and state-of-the-art experimental techniques and equipment have been developed to probe the structural and mechanical properties of biostructures from the micro- down to picoscale. Some of these experimental techniques include the optical or laser trap method, micropipette aspiration, step-pressure technique, atomic force microscopy and molecular force spectroscopy. In this article, we will review the basic principles and usage of these techniques to conduct single cell and single molecule biomechanics research

  7. Cancer Research

    Science.gov (United States)

    NCI is the nation's leader in cancer research. Learn more about NCI's cancer research areas, key initiatives, progress made in cancer research, and resources for researchers like research tools, specimens and data.

  8. Does single blind peer review hinder newcomers?

    NARCIS (Netherlands)

    Seeber, Marco; Bacchelli, A.

    2017-01-01

    Several fields of research are characterized by the coexistence of two different peer review modes to select quality contributions for scientific venues, namely double blind (DBR) and single blind (SBR) peer review. In the first, the identities of both authors and reviewers are not known to each

  9. Controlled generation of a single Trichel pulse and a series of single Trichel pulses in air

    Science.gov (United States)

    Mizeraczyk, Jerzy; Berendt, Artur; Akishev, Yuri

    2018-04-01

    In this paper, a simple method for the controlled generation of a single Trichel pulse or a series of single Trichel pulses of a regulated repetition frequency in air is proposed. The concept of triggering a single Trichel pulse or a series of such pulses is based on the precise controlling the voltage inception of the negative corona, which can be accomplished through the use of a ramp voltage pulse or a series of such pulses with properly chosen ramp voltage pulse parameters (rise and fall times, and ramp voltage pulse repetition frequency). The proposal has been tested in experiments using a needle-to-plate electrode arrangement in air, and reproducible Trichel pulses (single or in a series) were obtained by triggering them with an appropriately designed voltage waveform. The proposed method and results obtained have been qualitatively analysed. The analysis provides guidance for designing the voltage ramp pulse in respect of the generation of a single Trichel pulse or a series of single Trichel pulses. The controlled generation of a single Trichel pulse or a series of such pulses would be a helpful research tool for the refined studies of the fundamental processes in a negative corona discharge in a single- (air is an example) and multi-phase gaseous fluids. The controlled generation of a single Trichel pulse or a series of Trichel pulses can also be attractive for those corona treatments which need manipulation of the electric charge and heat portions delivered by the Trichel pulses to the object.

  10. Single sheet iron oxides

    DEFF Research Database (Denmark)

    Yin, Zhou

    activity. LDH single sheets have been reported to be effective sorbents, catalysts in electrochemical and photochemical reactions, and building thin films together with other nanomaterials for designing new functionalities. Here we focus on the delamination of FeII-FeIII LDHs into single sheet iron oxide...... was rapid compared to other iron oxides, reaching equilibrium within 60 minutes. Arsenic sorption and acid-base titration data could be successfully described with a 1pk Basic Stern Model (BSM). The point of zero charge was around 8. The intrinsic surface complexation equilibrium constants (log K...... became abundant at low pH. (3) Electrochemical reduction of chlorinated compounds using an SSI modified electrode. Here, the electrochemical reactivity of SSIs coated on indium tin oxide coated glass electrodes was investigated. Iron on the SSI modified electrode showed a typical Cyclic Voltammetry...

  11. Watching single molecules dance

    Science.gov (United States)

    Mehta, Amit Dinesh

    Molecular motors convert chemical energy, from ATP hydrolysis or ion flow, into mechanical motion. A variety of increasingly precise mechanical probes have been developed to monitor and perturb these motors at the single molecule level. Several outstanding questions can be best approached at the single molecule level. These include: how far does a motor progress per energy quanta consumed? how does its reaction cycle respond to load? how many productive catalytic cycles can it undergo per diffusional encounter with its track? and what is the mechanical stiffness of a single molecule connection? A dual beam optical trap, in conjunction with in vitro ensemble motility assays, has been used to characterize two members of the myosin superfamily: muscle myosin II and chick brain myosin V. Both move the helical polymer actin, but myosin II acts in large ensembles to drive muscle contraction or cytokinesis, while myosin V acts in small numbers to transport vesicles. An optical trapping apparatus was rendered sufficiently precise to identify a myosin working stroke with 1nm or so, barring systematic errors such as those perhaps due to random protein orientations. This and other light microscopic motility assays were used to characterize myosin V: unlike myosin II this vesicle transport protein moves through many increments of travel while remaining strongly bound to a single actin filament. The step size, stall force, and travel distance of myosin V reveal a remarkably efficient motor capable of moving along a helical track for over a micrometer without significantly spiraling around it. Such properties are fully consistent with the putative role of an organelle transport motor, present in small numbers to maintain movement over long ranges relative to cellular size scales. The contrast between myosin II and myosin V resembles that between a human running on the moon and one walking on earth, where the former allows for faster motion when in larger ensembles but for less

  12. Research about Research

    OpenAIRE

    2016-01-01

    Conté els articles següents: PhD Selection: Factors to take into account / Natalia Delgado, Tessy Troes, Meghana Sudhindra, and Helena Cuesta -- Portrait of a science disseminator / Beatriz Cabrero Daniel, Alberto Martínez-Rodríguez, Mari Celi Morales Muñoz and Carla Ten Ventura -- Social impact of Artificial Intelligence: Robotics / Kushagra Sharma, Manaswi Mishra, Siddharth Bhardwaj -- Is Interdisciplinary research the way to go? / Adrian Arroyo Perez, Giorgos Neokleous, Pantelis Stylianid...

  13. Single rotor turbine engine

    Science.gov (United States)

    Platts, David A.

    2002-01-01

    There has been invented a turbine engine with a single rotor which cools the engine, functions as a radial compressor, pushes air through the engine to the ignition point, and acts as an axial turbine for powering the compressor. The invention engine is designed to use a simple scheme of conventional passage shapes to provide both a radial and axial flow pattern through the single rotor, thereby allowing the radial intake air flow to cool the turbine blades and turbine exhaust gases in an axial flow to be used for energy transfer. In an alternative embodiment, an electric generator is incorporated in the engine to specifically adapt the invention for power generation. Magnets are embedded in the exhaust face of the single rotor proximate to a ring of stationary magnetic cores with windings to provide for the generation of electricity. In this alternative embodiment, the turbine is a radial inflow turbine rather than an axial turbine as used in the first embodiment. Radial inflow passages of conventional design are interleaved with radial compressor passages to allow the intake air to cool the turbine blades.

  14. Single scattering properties of hydrosols

    Science.gov (United States)

    Mukherjee, L.; Zhai, P.; Hu, Y.

    2017-12-01

    The single scattering or inherent optical properties (IOPs) of hydrosols play an important role in the complete study of ocean optics, ocean color remote sensing, and ocean biogeochemistry research. Measurements show that hydrosols can be of various sizes and shapes, which suggests that general non-spherical models should be considered for the study of IOPs of hydrosols. In this work, the IOPs of randomly oriented non-spherical hydrosols of both absorbing and non-absorbing types are modeled using the Amsterdam Discrete Dipole Approximation (ADDA). We have defined the degree of optical non-sphericity (DONS) and investigated the dependence of DONS on refractive indices, sizes, and aspect ratios. For particles with non-unit aspect ratios, the magnitude of DONS increases with an increase of refractive index and aspect ratio. In general, the value of DONS increases with increase in particle size. The variation of DONS with respect to refractive indices and aspect ratios of the hydrosols makes it an important parameter in the study of ocean optics. Dependence of backscattering fraction on non-sphericity, size, and aspect ratio of the hydrosols is also demonstrated. The modeling of single scattering properties of hydrosols with different microphysical parameters would help to interpret the ocean radiation field measured by in situ or remote sensing sensors. Understanding the IOPs of hydrosols would lead to better radiative transfer models in ocean waters and new remote sensing technologies of hydrosol compositions.

  15. Stress Level and Adversity Quotient among Single Working Mothers

    Directory of Open Access Journals (Sweden)

    Dianne Bautista Solis

    2015-12-01

    Full Text Available The study identified the profile of the single working mothers in terms of number of children, number of years as a single parent and reason for being a single parent; assessed the single mothers’ stress level and adversity quotient; determined the significant difference of stress level and adversity quotient of single mothers when grouped according to profile variables; determined the best predictor of stress level and adversity quotient. Moreover this research endeavoured to test significant relationship between the adversity quotient and stress level of single working mothers. Lastly, it proposed a stress management program for single working mothers for them to cope with their stress and adversities in life. The researcher employed quantitative method using standardized questionnaires namely Depression, Anxiety, Stress Scale (DASS and Adversity Response Profile (ARP. The respondents were twenty five (25 single working mothers of the students of Batangas State University. From the results, majority of the respondents have 3 children, widow and in early years as single parent; with a normal level of stress and an average adversity quotient.. There are no significant differences on the stress level and adversity quotient of the respondents when grouped according to profile variables. Finally, stress level has no significant effect on adversity quotient of single working mothers. From the findings, the researcher further recommends that the Office of Guidance and Counseling should update the student information database to determine students with a single working mother. The Parent-Teacher Association may form a single-parent subgroup for the single working mothers to be able to identify to other mothers with same situation. Moreover, the proposed stress management program may be reviewed and implemented by the Office of Guidance and Counseling in coordination with the Parent-Teacher Association of Batangas State University. Future researchers

  16. Uniform Single Valued Neutrosophic Graphs

    Directory of Open Access Journals (Sweden)

    S. Broumi

    2017-09-01

    Full Text Available In this paper, we propose a new concept named the uniform single valued neutrosophic graph. An illustrative example and some properties are examined. Next, we develop an algorithmic approach for computing the complement of the single valued neutrosophic graph. A numerical example is demonstrated for computing the complement of single valued neutrosophic graphs and uniform single valued neutrosophic graph.

  17. The Meaning of "Being Single" for Mormon College-Age Single Adults

    OpenAIRE

    Darrington, Jana

    2003-01-01

    This study researched the meaning of being single among 24 college-age adults of The Church of Jesus Christ of Latter-day Saints (i.e., Mormons). It examined influences on the construction of meanings of singlehood, gender patterns regarding the meaning of singlehood, and pressures on L.D.S. singles to date and marry. The most important finding was that positive attitudes toward singlehood are more prevalent than negative or ambivalent attitudes. Families, as gate-keepers and transmitters ...

  18. [Music therapy single case research--a qualitative approach].

    Science.gov (United States)

    Langenberg, M; Frommer, J; Tress, W

    1995-12-01

    A qualitative approach for describing music psychotherapy treatment is developed. For this purpose we employ the methodological principle of triangulation of perspectives (patient, therapist, independent observers, composers). Our approach is based on the concept of the resonator function describing the perceptive capacity of all participants for effective and relationship-referred significance of the work produced during the treatment. The qualitative method importing and extending the knowledge of the inner context of the case is illustrated by two musical improvisations from the treatment of a female patient suffering from chronic migraine.

  19. Single Electrode Heat Effects

    DEFF Research Database (Denmark)

    Jacobsen, Torben; Broers, G. H. J.

    1977-01-01

    The heat evolution at a single irreversibly working electrode is treated onthe basis of the Brønsted heat principle. The resulting equation is analogous to the expression for the total heat evolution in a galvanic cellwith the exception that –DeltaS is substituted by the Peltier entropy, Delta......SP, of theelectrode reaction. eta is the overvoltage at the electrode. This equation is appliedto a high temperature carbonate fuel cell. It is shown that the Peltier entropyterm by far exceeds the heat production due to the irreversible losses, and thatthe main part of heat evolved at the cathode is reabsorbed...

  20. Attitudes Toward the Ethics of Research Using Social Media: A Systematic Review.

    Science.gov (United States)

    Golder, Su; Ahmed, Shahd; Norman, Gill; Booth, Andrew

    2017-06-06

    . Guidelines on ethical conduct should be based on current evidence and standardized to avoid discrepancies between, and duplication across, different institutions, taking into consideration different jurisdictions. ©Su Golder, Shahd Ahmed, Gill Norman, Andrew Booth. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 06.06.2017.

  1. Coherent manipulation of single spins in semiconductors.

    Science.gov (United States)

    Hanson, Ronald; Awschalom, David D

    2008-06-19

    During the past few years, researchers have gained unprecedented control over spins in the solid state. What was considered almost impossible a decade ago, in both conceptual and practical terms, is now a reality: single spins can be isolated, initialized, coherently manipulated and read out using both electrical and optical techniques. Progress has been made towards full control of the quantum states of single and coupled spins in a variety of semiconductors and nanostructures, and towards understanding the mechanisms through which spins lose coherence in these systems. These abilities will allow pioneering investigations of fundamental quantum-mechanical processes and provide pathways towards applications in quantum information processing.

  2. Single photons on demand

    International Nuclear Information System (INIS)

    Grangier, P.; Abram, I.

    2004-01-01

    Quantum cryptography and information processing are set to benefit from developments in novel light sources that can emit photons one by one. Quantum mechanics has gained a reputation for making counter-intuitive predictions. But we rarely get the chance to witness these effects directly because, being humans, we are simply too big. Take light, for example. The light sources that are familiar to us, such as those used in lighting and imaging or in CD and DVD players, are so huge that they emit billions and billions of photons. But what if there was a light source that emitted just one photon at a time? Over the past few years, new types of light source that are able to emit photons one by one have been emerging from laboratories around the world. Pulses of light composed of a single photon correspond to power flows in the femtowatt range - a million billion times less than that of a table lamp. The driving force behind the development of these single-photon sources is a range of novel applications that take advantage of the quantum nature of light. Quantum states of superposed and entangled photons could lead the way to guaranteed-secure communication, to information processing with unprecedented speed and efficiency, and to new schemes for quantum teleportation. (U.K.)

  3. Single-borehole techniques

    International Nuclear Information System (INIS)

    Klotz, D.; Moser, H.; Trimborn, P.

    1978-01-01

    Proceeding on the theoretical considerations and on the experience and practice derived from laboratory and field testing, a system consisting of tracer injection units, detector units, measuring probe units and packers is presented, from which the different borehole probes required can be combined. A couple of examples of recent applications shows the position of the Single-Borehole Techniques with respect to the traditional methods used for the measurement of the ground-water flow. A confrontation of the permeabilities of different aquifers consents, both on the basis of the Single-Borehole Techniques as by pumping experiments, the determination of the reliability of the Point-Dilution-Method. The Point-Dilution-Method is giving information about the vertical and horizontal distribution of the permeabilities in an aquifer. By measuring the vertical current in two karst wells, the tributary horizons of a well have been determined, which gave valuable information for the subsequent well construction. Local leakages could be detected by measuring the vertical flow rate through observation wells arranged along a grout curtain erected on both sides of the retaining barrage of the Keban dam. (orig.) [de

  4. Heralded single-photon absorption by a single atom

    Science.gov (United States)

    Piro, N.; Rohde, F.; Schuck, C.; Almendros, M.; Huwer, J.; Ghosh, J.; Haase, A.; Hennrich, M.; Dubin, F.; Eschner, J.

    2011-01-01

    Emission and absorption of single photons by single atoms is a fundamental limit of matter-light interaction, manifesting its quantum mechanical nature. As a controlled process, it is also a key tool in quantum optical information technology . Controlled single-photon emission is well advanced ; for controlled single-photon absorption by a single atom, proposals exist but only preliminary experimental steps have been taken . Here we report the absorption of single photons by a single trapped ion: employing a photon pair source, detection of the quantum-correlated partner photon heralds the presence of the resonant photon at the atom. We find clear correlations between the detection of the herald and the absorption process in the atom; we also demonstrate polarization control of this process. Our experiment evidences previously unexplored interaction between a single absorber and a quantum light source; with improved control over the coupling, it will open up new avenues in quantum technology.

  5. A single broken thread

    DEFF Research Database (Denmark)

    Douglas-Jones, Rachel

    2012-01-01

    In exploring the work and role of ethics review committees in Asia, this paper takes as its starting point an image of a finely woven silk cloth. The image was used at an international conference to describe the ‘matrix’ of persons and institutions involved in biomedical research, with the implic......In exploring the work and role of ethics review committees in Asia, this paper takes as its starting point an image of a finely woven silk cloth. The image was used at an international conference to describe the ‘matrix’ of persons and institutions involved in biomedical research...... ethics committees in the Asian region, I show how the image can be used to understand the place of ethics as a contemporary concern in research settings....

  6. 75 FR 9247 - Single Family Mortgage Insurance Premium, Single Family

    Science.gov (United States)

    2010-03-01

    ... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5376-N-13] Single Family Mortgage Insurance Premium, Single Family AGENCY: Office of the Chief Information Officer, HUD. ACTION: Notice... is soliciting public comments on the subject proposal. Lenders use the Single Family Premium...

  7. IT Tools for Teachers and Scientists, Created by Undergraduate Researchers

    Science.gov (United States)

    Millar, A. Z.; Perry, S.

    2007-12-01

    of a multi-media, general education curriculum at University of Southern California. Throughout this meeting, at the SCEC booth, UseIT interns will be demonstrating both the serious games and SCEC-VDO. SCEC/UseIT is a National Science Foundation Research Experience for Undergraduates site.

  8. Social Work Research

    DEFF Research Database (Denmark)

    Social work research has gathered a greater transparency and clarity of identity in North American and parts of Europe. Furthermore, the rapid emergence of social work research in other European countries, China, India, Japan and elsewhere in Asia and Pacific Rim countries, and gradually in South...... America, has created a need for a collection that can contribute to both shaping and making accessible key and sometimes hard-to-access sources. This four-volume collection answers this need, bringing together key literature in a single resource and structuring it into thematic volumes to enable clear...... understanding of the different aspects involved in the research. Volume One: Historical Trajectories, Purposes and Key Concepts Volume Two: Key Decisions about Research Strategy Volume Three: The Practice of Social Work Research Volume Four: The Contexts of Social Work Research...

  9. Isotropic Single Negative Metamaterials

    Directory of Open Access Journals (Sweden)

    P. Protiva

    2008-09-01

    Full Text Available This paper presents the application of simple, and therefore cheap, planar resonators for building 3D isotropic metamaterials. These resonators are: a broadside-coupled split ring resonator with a magnetic response providing negative permeability; an electric dipole terminated by a loop inductor together with a double H-shaped resonator with an electric response providing negative permittivity. Two kinds of 3D isotropic single negative metamaterials are reported. The first material consists of unit cells in the form of a cube bearing on its faces six equal planar resonators with tetrahedral symmetry. In the second material, the planar resonators boxed into spherical plastic shells and randomly distributed in a hosting material compose a real 3D volumetric metamaterial with an isotropic response. In both cases the metamaterial shows negative permittivity or permeability, according to the type of resonators that are used. The experiments prove the isotropic behavior of the cells and of the metamaterial specimens.

  10. Lanthanide single molecule magnets

    CERN Document Server

    Tang, Jinkui

    2015-01-01

    This book begins by providing basic information on single-molecule magnets (SMMs), covering the magnetism of lanthanide, the characterization and relaxation dynamics of SMMs, and advanced means of studying lanthanide SMMs. It then systematically introduces lanthanide SMMs ranging from mononuclear and dinuclear to polynuclear complexes, classifying them and highlighting those SMMs with high barrier and blocking temperatures – an approach that provides some very valuable indicators for the structural features needed to optimize the contribution of an Ising type spin to a molecular magnet. The final chapter presents some of the newest developments in the lanthanide SMM field, such as the design of multifunctional and stimuli-responsive magnetic materials as well as the anchoring and organization of the SMMs on surfaces. In addition, the crystal structure and magnetic data are clearly presented with a wealth of illustrations in each chapter, helping newcomers and experts alike to better grasp ongoing trends and...

  11. Coronary single vessel disease

    International Nuclear Information System (INIS)

    Kaltenbach, M.; Kober, G.; Satter, P.; Gruentzig, A.; Myler, R.; Sterzer, S.

    1980-01-01

    The seven-years-survival rate is about 80 percent with respect to the most favourable long-time prognosis for coronary single vessel diseases under conservative therapy. In this contribution the control angiography of 76 patients after aorto-coronary bypass operation or transluminal angioplastic is reported. Only two patients subjected to a bypass operation. The recidivity rate is 10 percent after an operation, whereby it is not possible to make a recidivity prognosis. If a recidivity shows up it is being developped during the first three months. If the control angiography three months after the operation shows a good result, then a favourable steady state result can be expected. A comparison of the result with four different centers is given. (APR) [de

  12. Single-Molecule Nanomagnets

    Science.gov (United States)

    Friedman, Jonathan R.; Sarachik, Myriam P.

    2010-04-01

    Single-molecule magnets straddle the classical and quantum mechanical worlds, displaying many fascinating phenomena. They may have important technological applications in information storage and quantum computation. We review the physical properties of two prototypical molecular nanomagnets, Mn12-acetate and Fe8: Each behaves as a rigid, spin-10 object and exhibits tunneling between up and down directions. As temperature is lowered, the spin-reversal process evolves from thermal activation to pure quantum tunneling. At low temperatures, magnetic avalanches occur in which the magnetization of an entire sample rapidly reverses. We discuss the important role that symmetry-breaking fields play in driving tunneling and in producing Berry-phase interference. Recent experimental advances indicate that quantum coherence can be maintained on timescales sufficient to allow a meaningful number of quantum computing operations to be performed. Efforts are under way to create monolayers and to address and manipulate individual molecules.

  13. Single Nucleotide Polymorphism

    DEFF Research Database (Denmark)

    Børsting, Claus; Pereira, Vania; Andersen, Jeppe Dyrberg

    2014-01-01

    and briefly describe the methods that are preferred for SNP typing in forensic genetics. In addition, we will illustrate how SNPs can be used as investigative leads in the police investigation by discussing the use of ancestry informative markers and forensic DNA phenotyping. Modern DNA sequencing......Single nucleotide polymorphisms (SNPs) are the most frequent DNA sequence variations in the genome. They have been studied extensively in the last decade with various purposes in mind. In this chapter, we will discuss the advantages and disadvantages of using SNPs for human identification...... technologies (also called next generation sequencing or NGS) have the potential to completely transform forensic genetic investigations as we know them today. Here, we will make a short introduction to NGS and explain how NGS may combine analysis of the traditional forensic genetic markers with analysis...

  14. Lanthanide single molecule magnets

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Jinkui; Zhang, Peng [Chinese Academy of Sciences, Changchun (China). Changchun Inst. of Applied Chemistry

    2015-10-01

    This book begins by providing basic information on single-molecule magnets (SMMs), covering the magnetism of lanthanide, the characterization and relaxation dynamics of SMMs and advanced means of studying lanthanide SMMs. It then systematically introduces lanthanide SMMs ranging from mononuclear and dinuclear to polynuclear complexes, classifying them and highlighting those SMMs with high barrier and blocking temperatures - an approach that provides some very valuable indicators for the structural features needed to optimize the contribution of an Ising type spin to a molecular magnet. The final chapter presents some of the newest developments in the lanthanide SMM field, such as the design of multifunctional and stimuli-responsive magnetic materials as well as the anchoring and organization of the SMMs on surfaces. In addition, the crystal structure and magnetic data are clearly presented with a wealth of illustrations in each chapter, helping newcomers and experts alike to better grasp ongoing trends and explore new directions.

  15. Investigation of Chirality Selection Mechanism of Single Walled Carbon Nanotube

    Science.gov (United States)

    2016-12-13

    AFRL-AFOSR-JP-TR-2017-0007 Investigation of Chirality Selection Mechanism of Single -Walled Carbon Nanotube Seun Min Kim KOREA INSTITUTE OF SCIENCE...Selection Mechanism of Single -Walled Carbon Nanotube 5a.  CONTRACT NUMBER 5b.  GRANT NUMBER FA2386-15-1-4099 5c.  PROGRAM ELEMENT NUMBER 61102F 6. AUTHOR...research involved investigation of two fundamental mechanisms of carbon nanotube (CNT) growth: chirality selection of single -walled CNT (SWCNT) and

  16. Single Atoms in Nearly Concentric Cavity

    Science.gov (United States)

    Utama, Adrian Nugraha; Nguyen, Chi Huan; Lewty, Nick; Kurtsiefer, Christian; Quantum Optics Group Team

    2017-04-01

    Strong interaction between photons and neutral single atoms are usually observed in cavity quantum electrodynamics (CQED) systems with high finesse mirrors and small physical volume. We demonstrate another approach that employs a near concentric cavity with relatively low finesse mirrors ( 100) and large physical separation between mirrors ( 10 mm). The transmission spectrum of our CQED system with trapped single atoms is observed to exhibit two resolved normal mode peaks, in which the single atom cooperativity is estimated to be around 0.4. The cooperativity of the system can be improved further by increasing the finesse of the mirrors or moving the cavity closer to the concentric point. The successful realization of concentric CQED systems will open opportunities for scaling up with applications in quantum computing. This work is supported by the National Research Foundation and Ministry of Education, Singapore.

  17. Research organizations

    DEFF Research Database (Denmark)

    Larsen, Bøje; Aagaard, Peter

    in Copenhagen - we argue that a post-rational form of research activity is emerging which revert these features. We term this new type of research "enchanted research", "sciencetainment" and "Mode2-b research". The factors that facilitate this development include the boring style of conventional research...

  18. Automated data collection in single particle electron microscopy

    Science.gov (United States)

    Tan, Yong Zi; Cheng, Anchi; Potter, Clinton S.; Carragher, Bridget

    2016-01-01

    Automated data collection is an integral part of modern workflows in single particle electron microscopy (EM) research. This review surveys the software packages available for automated single particle EM data collection. The degree of automation at each stage of data collection is evaluated, and the capabilities of the software packages are described. Finally, future trends in automation are discussed. PMID:26671944

  19. 29 CFR 1926.66 - Criteria for design and construction of spray booths.

    Science.gov (United States)

    2010-07-01

    ... between moving parts and the duct or fan housing. Fan blades shall be mounted on a shaft sufficiently heavy to maintain perfect alignment even when the blades of the fan are heavily loaded, the shaft...

  20. Improved 64-bit Radix-16 Booth Multiplier Based on Partial Product Array Height Reduction

    DEFF Research Database (Denmark)

    Antelo, Elisardo; Montuschi, Paolo; Nannarelli, Alberto

    2016-01-01

    , a reduction of one unit in the maximum height is achieved. This reduction may add flexibility during the design of the pipelined multiplier to meet the design goals, it may allow further optimizations of the partial product array reduction stage in terms of area/delay/power and/or may allow additional addends...

  1. Research vessels

    Digital Repository Service at National Institute of Oceanography (India)

    Rao, P.S.

    The role of the research vessels as a tool for marine research and exploration is very important. Technical requirements of a suitable vessel and the laboratories needed on board are discussed. The history and the research work carried out...

  2. SSD for R: A Comprehensive Statistical Package to Analyze Single-System Data

    Science.gov (United States)

    Auerbach, Charles; Schudrich, Wendy Zeitlin

    2013-01-01

    The need for statistical analysis in single-subject designs presents a challenge, as analytical methods that are applied to group comparison studies are often not appropriate in single-subject research. "SSD for R" is a robust set of statistical functions with wide applicability to single-subject research. It is a comprehensive package…

  3. Modeling and Development of Superconducting Nanowire Single Photon Detectors

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposal outlines a research project as the central component of a Ph.D. program focused on the device physics of superconducting nanowire single photon...

  4. Research reports (Annual reports)

    International Nuclear Information System (INIS)

    1975-05-01

    This compilation of research reports is the third one to be published once a year in the frame of a comprehensive reporting on current investigations with regard to reactor safety. There are three types of reports: RS Research Reports, LRA Research Reports, GFK Research Reports. The RS Research Reports and the LRA Research Reports give information on the investigations sponsored by the Bundesminister fuer Forschung und Technologie (BMFT) and partly by the Bundesminister des Innern (BMI [SR 100, At T 85 a]) as individual reactor safety research projects. The GFK Research Reports inform about theoretical and experimental investigations on reactor safety conducted by the Gesellschaft fuer Kernforschung mbH (GFK), Karlsruhe. The Laboratorium fuer Reaktorregelung und Anlagensicherung (LRA), Muenchen-Garching, executes nine individual research projects comprehended under number At T 85 a. The work carried out by the GFK is included in the main project 'Nuclear Safety' (PNS). The single reports are attached to the main parts and focal points of the Research Program Reactor Safety. Therefore, at the head of the reports, under 'Project Number', not only the RS-, LRA- or GFK-Number but also the number of the main part of the Research Program which the reported investigation contributes to is noted. (orig.) [de

  5. A single particle energies

    Energy Technology Data Exchange (ETDEWEB)

    Bodmer, A.R. [Illinois Univ., Chicago, IL (United States). Dept. of Physics]|[Argonne National Lab., IL (United States); Usmani, Q.N.; Sami, M. [Jamia Millia Islamia, New Delhi (India). Dept. of Physics

    1993-09-01

    We consider the binding energies of {Lambda} hypernuclei (HN), in particular the single-particle (s.p.) energy data, which have been obtained for a wide range of HN with mass numbers A {le} 89 and for orbital angular momenta {ell}{sub {Lambda}} {le} 4. We briefly review some of the relevant properties of A hypernuclei. These are nuclei {sub {Lambda}}{sup A}Z with baryon number A in which a single {Lambda} hyperon (baryon number = 1) is bound to an ordinary nucleus {sup A}Z consisting of A - 1 nucleons = Z protons + N neutrons. The {Lambda} hyperon is neutral, has spin 1/2, strangeness S = {minus}1, isospin I = O and a mass M{sub {Lambda}} = 1116 MeV/c{sup 2}. Although the {Lambda} interacts with a nucleon, its interaction is only about half as strong as that between two nucleons, and thus very roughly V{sub {Lambda}N} {approx} 0.5 V{sub NN}. As a result, the two-body {Lambda}N system is unbound, and the lightest bound HN is the three-body hypertriton {sub {Lambda}}{sup 3}H in which the {Lambda} is bound to a deuteron with the {Lambda}-d separation energy being only {approx} 0.1 MeV corresponding to an exponential tail of radius {approx} 15 fm! In strong interactions the strangeness S is of course conserved, and the {Lambda} is distinct from the nucleons. In a HN strangeness changes only in the weak decays of the {Lambda} which can decay either via ``free`` pionic decay {Lambda} {yields} N + {pi} or via induced decay {Lambda} + N {yields} N + N which is only possible in the presence of nucleons. Because of the small energy release the pionic decay is strongly suppressed in all but the lightest HN and the induced decay dominates. However, the weak decay lifetime {approx} 10{sup {minus}10}s is in fact close to the lifetime of a free {Lambda}. Since this is much longer than the strong interaction time {approx} 10{sup {minus}22}s we can ignore the weak interactions when considering the binding of HN, just as for ordinary nuclei.

  6. A single particle energies

    International Nuclear Information System (INIS)

    Bodmer, A.R.; Usmani, Q.N.; Sami, M.

    1993-01-01

    We consider the binding energies of Λ hypernuclei (HN), in particular the single-particle (s.p.) energy data, which have been obtained for a wide range of HN with mass numbers A ≤ 89 and for orbital angular momenta ell Λ ≤ 4. We briefly review some of the relevant properties of A hypernuclei. These are nuclei Λ A Z with baryon number A in which a single Λ hyperon (baryon number = 1) is bound to an ordinary nucleus A Z consisting of A - 1 nucleons = Z protons + N neutrons. The Λ hyperon is neutral, has spin 1/2, strangeness S = -1, isospin I = O and a mass M Λ = 1116 MeV/c 2 . Although the Λ interacts with a nucleon, its interaction is only about half as strong as that between two nucleons, and thus very roughly V ΛN ∼ 0.5 V NN . As a result, the two-body ΛN system is unbound, and the lightest bound HN is the three-body hypertriton Λ 3 H in which the Λ is bound to a deuteron with the Λ-d separation energy being only ∼ 0.1 MeV corresponding to an exponential tail of radius ∼ 15 fm exclamation point In strong interactions the strangeness S is of course conserved, and the Λ is distinct from the nucleons. In a HN strangeness changes only in the weak decays of the Λ which can decay either via ''free'' pionic decay Λ → N + π or via induced decay Λ + N → N + N which is only possible in the presence of nucleons. Because of the small energy release the pionic decay is strongly suppressed in all but the lightest HN and the induced decay dominates. However, the weak decay lifetime ∼ 10 -10 s is in fact close to the lifetime of a free Λ. Since this is much longer than the strong interaction time ∼ 10 -22 s we can ignore the weak interactions when considering the binding of HN, just as for ordinary nuclei

  7. Research organizations

    DEFF Research Database (Denmark)

    Larsen, Bøje; Aagaard, Peter

    in Copenhagen - we argue that a post-rational form of research activity is emerging which revert these features. We term this new type of research "enchanted research", "sciencetainment" and "Mode2-b research". The factors that facilitate this development include the boring style of conventional research......, growing competition for research funds, more project funding compared to institutional funding and a demand for accountability. Countervailing forces also exist, however....

  8. Single Molecule Spectroscopy of Electron Transfer

    International Nuclear Information System (INIS)

    Holman, Michael; Zang, Ling; Liu, Ruchuan; Adams, David M.

    2009-01-01

    The objectives of this research are threefold: (1) to develop methods for the study electron transfer processes at the single molecule level, (2) to develop a series of modifiable and structurally well defined molecular and nanoparticle systems suitable for detailed single molecule/particle and bulk spectroscopic investigation, (3) to relate experiment to theory in order to elucidate the dependence of electron transfer processes on molecular and electronic structure, coupling and reorganization energies. We have begun the systematic development of single molecule spectroscopy (SMS) of electron transfer and summaries of recent studies are shown. There is a tremendous need for experiments designed to probe the discrete electronic and molecular dynamic fluctuations of single molecules near electrodes and at nanoparticle surfaces. Single molecule spectroscopy (SMS) has emerged as a powerful method to measure properties of individual molecules which would normally be obscured in ensemble-averaged measurement. Fluctuations in the fluorescence time trajectories contain detailed molecular level statistical and dynamical information of the system. The full distribution of a molecular property is revealed in the stochastic fluctuations, giving information about the range of possible behaviors that lead to the ensemble average. In the case of electron transfer, this level of understanding is particularly important to the field of molecular and nanoscale electronics: from a device-design standpoint, understanding and controlling this picture of the overall range of possible behaviors will likely prove to be as important as designing ia the ideal behavior of any given molecule.

  9. Technologies for Single-Cell Isolation.

    Science.gov (United States)

    Gross, Andre; Schoendube, Jonas; Zimmermann, Stefan; Steeb, Maximilian; Zengerle, Roland; Koltay, Peter

    2015-07-24

    The handling of single cells is of great importance in applications such as cell line development or single-cell analysis, e.g., for cancer research or for emerging diagnostic methods. This review provides an overview of technologies that are currently used or in development to isolate single cells for subsequent single-cell analysis. Data from a dedicated online market survey conducted to identify the most relevant technologies, presented here for the first time, shows that FACS (fluorescence activated cell sorting) respectively Flow cytometry (33% usage), laser microdissection (17%), manual cell picking (17%), random seeding/dilution (15%), and microfluidics/lab-on-a-chip devices (12%) are currently the most frequently used technologies. These most prominent technologies are described in detail and key performance factors are discussed. The survey data indicates a further increasing interest in single-cell isolation tools for the coming years. Additionally, a worldwide patent search was performed to screen for emerging technologies that might become relevant in the future. In total 179 patents were found, out of which 25 were evaluated by screening the title and abstract to be relevant to the field.

  10. Single-molecule manipulation and detection.

    Science.gov (United States)

    Zhao, Deyu; Liu, Siyun; Gao, Ying

    2018-01-25

    Compared to conventional ensemble methods, studying macromolecules at single-molecule level can reveal extraordinary clear and even surprising views for a biological reaction. In the past 20 years, single-molecule techniques have been undergoing a very rapid development, and these cutting edge technologies have revolutionized the biological research by facilitating single-molecule manipulation and detection. Here we give a brief review about these advanced techniques, including optical tweezers, magnetic tweezers, atomic force microscopy (AFM), hydrodynamic flow-stretching assay, and single-molecule fluorescence resonance energy transfer (smFRET). We are trying to describe their basic principles and provide a few examples of applications for each technique. This review aims to give a rather introductory survey of single-molecule techniques for audiences with biological or biophysical background. © The Author(s) 2018. Published by Oxford University Press on behalf of the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  11. The single entity option

    International Nuclear Information System (INIS)

    Friedlander, M.C.; Roberts, K.M.

    1997-01-01

    Traditionally, an owner hires an engineer to design a power facility or other project and then circulates the completed plans to several contractors for competitive bidding. Although there are many variations on this theme, there is an alternative method which is growing in popularity--the design-build concept. In this construction method, the same entity designs and constructs the facility. The design builder may be a single firm with both design and construction capacity in-house, or it may be a combination of two or more firms with complementary abilities. If there are multiple firms, they may be structured as a joint venture or with one of the firms prime and the others in a subcontracting role. The critical aspect is that the owner contracts with one entity which has the responsibility for both designing and constructing the facility. According to statistics compiled by the Design-Build Institute of America and F.W. Dodge DATALINE2, a national reporter of construction statistics and information, from April 1995 to April 1996 the number of design-build contracts increased 103 percent over the previous year. Of a total $212 billion construction market, about $37.2 billion--18 percent--was design build. The strongest growth was in the category of industrial--plants, refineries, factories and warehouses--in which the concept use was up more than 300 percent from the previous year

  12. Singled Out for Success: A Narrative Inquiry of Single Mothers in the Community College

    Science.gov (United States)

    Bober, Delia A.

    2017-01-01

    The purpose of this qualitative study was to explore and understand single-mother community college students' perceptions of their ability to succeed. The theoretical framework that guided this research was Bandura's (1977) social cognitive theory concept of self-efficacy, defined as a person's belief in his or her ability to succeed. Given…

  13. Single molecule SERS: Perspectives of analytical applications

    Czech Academy of Sciences Publication Activity Database

    Vlčková, B.; Pavel, I.; Sládková, M.; Šišková, K.; Šlouf, Miroslav

    834-836, - (2007), s. 42-47 ISSN 0022-2860. [European Congress on Molecular Spectroscopy /28./. Istanbul, 03.09.2006-08.09.2006] R&D Projects: GA ČR GA203/04/0688 Institutional research plan: CEZ:AV0Z40500505 Keywords : surface-enhanced Raman scattering (SERS) * surface-enhanced resonance Raman (SERRS) * single molecule SERS Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.486, year: 2007

  14. NASA's Student Airborne Research Program as a model for effective professional development experience in Oceanography

    Science.gov (United States)

    Palacios, S. L.; Kudela, R. M.; Clinton, N. E.; Atkins, N.; Austerberry, D.; Johnson, M.; McGonigle, J.; McIntosh, K.; O'Shea, J. J.; Shirshikova, Z.; Singer, N.; Snow, A.; Woods, R.; Schaller, E.; Shetter, R. E.

    2011-12-01

    With over half of the current earth and space science workforce expected to retire within the next 15 years, NASA has responded by cultivating young minds through programs such as the Student Airborne Research Program (SARP). SARP is a competitive internship that introduces upper-level undergraduates and early graduate students to Earth System Science research and NASA's Airborne Science Program. The program serves as a model for recruitment of very high caliber students into the scientific workforce. Its uniqueness derives from total vertical integration of hands-on experience at every stage of airborne science: aircraft instrumentation, flight planning, mission participation, field-work, analysis, and reporting of results in a competitive environment. At the conclusion of the program, students presented their work to NASA administrators, faculty, mentors, and the other participants with the incentive of being selected as best talk and earning a trip to the fall AGU meeting to present their work at the NASA booth. We hope lessons learned can inform the decisions of scientists at the highest levels seeking to broaden the appeal of research. In 2011, SARP was divided into three disciplinary themes: Oceanography, Land Use, and Atmospheric Chemistry. Each research group was mentored by an upper-level graduate student who was supervised by an expert faculty member. A coordinator managed the program and was supervised by a senior research scientist/administrator. The program is a model of knowledge transfer among the several levels of research: agency administration to the program coordinator, established scientific experts to the research mentors, and the research mentors to the pre-career student participants. The outcomes from this program include mission planning and institutional knowledge transfer from administrators and expert scientists to the coordinator and research mentors; personnel and project management from the coordinator and expert scientists to the

  15. Handbook of statistical methods single subject design

    CERN Document Server

    Satake, Eiki; Maxwell, David L

    2008-01-01

    This book is a practical guide of the most commonly used approaches in analyzing and interpreting single-subject data. It arranges the methodologies used in a logical sequence using an array of research studies from the existing published literature to illustrate specific applications. The book provides a brief discussion of each approach such as visual, inferential, and probabilistic model, the applications for which it is intended, and a step-by-step illustration of the test as used in an actual research study.

  16. Single-Word Recognition Need Not Depend on Single-Word Features: Narrative Coherence Counteracts Effects of Single-Word Features That Lexical Decision Emphasizes

    Science.gov (United States)

    Teng, Dan W.; Wallot, Sebastian; Kelty-Stephen, Damian G.

    2016-01-01

    Research on reading comprehension of connected text emphasizes reliance on single-word features that organize a stable, mental lexicon of words and that speed or slow the recognition of each new word. However, the time needed to recognize a word might not actually be as fixed as previous research indicates, and the stability of the mental lexicon…

  17. Connecting the Space between Design and Research: Explorations in Participatory Research Supervision

    Science.gov (United States)

    Caldwell, Glenda Amayo; Osborne, Lindy; Mewburn, Inger; Nottingham, Anitra

    2016-01-01

    In this article we offer a single case study using an action research method for gathering and analysing data offering insights valuable to both design and research supervision practice. We do not attempt to generalise from this single case, but offer it as an instance that can improve our understanding of research supervision practice. We…

  18. Light Emitting Transistors of Organic Single Crystals

    Science.gov (United States)

    Iwasa, Yoshihiro

    2009-03-01

    Organic light emitting transistors (OLETs) are attracting considerable interest as a novel function of organic field effect transistors (OFETs). Besides a smallest integration of light source and current switching devices, OLETs offer a new opportunity in the fundamental research on organic light emitting devices. The OLET device structure allows us to use organic single crystals, in contrast to the organic light emitting diodes (OLEDs), the research of which have been conducted predominantly on polycrystalline or amorphous thin films. In the case of OFETs, use of single crystals have produced a significant amount of benefits in the studies of pursuit for the highest performance limit of FETs, intrinsic transport mechanism in organic semiconductors, and application of the single crystal transistors. The study on OLETs have been made predominantly on polycrystalline films or multicomponent heterojunctions, and single crystal study is still limited to tetracene [1] and rubrene [2], which are materials with relatively high mobility, but with low photoluminescence efficiency. In this paper, we report fabrication of single crystal OLETs of several kinds of highly luminescent molecules, emitting colorful light, ranging from blue to red. Our strategy is single crystallization of monomeric or oligomeric molecules, which are known to have a very high photoluminescence efficiency. Here we report the result on single crystal LETs of rubrene (red), 4,4'-bis(diphenylvinylenyl)-anthracene (green), 1,4-bis(5-phenylthiophene-2-yl)benzene (AC5) (green), and 1,3,6,8-tetraphenylpyrene (TPPy) (blue), all of which displayed ambipolar transport as well as peculiar movement of voltage controlled movement of recombination zone, not only from the surface of the crystal but also from the edges of the crystals, indicting light confinement inside the crystal. Realization of ambipolar OLET with variety of single crystals indicates that the fabrication method is quite versatile to various light

  19. Single-dopant resonance in a single-electron transistor

    OpenAIRE

    Golovach, V. N.; Jehl, X.; Houzet, M.; Pierre, M.; Roche, B.; Sanquer, M.; Glazman, L. I.

    2011-01-01

    Single dopants in semiconductor nanostructures have been studied in great details recently as they are good candidates for quantum bits, provided they are coupled to a detector. Here we report coupling of a single As donor atom to a single-electron transistor (SET) in a silicon nanowire field-effect transistor. Both capacitive and tunnel coupling are achieved, the latter resulting in a dramatic increase of the conductance through the SET, by up to one order of magnitude. The experimental resu...

  20. Action Research and Interactive Research

    DEFF Research Database (Denmark)

    Svensson, lennart; Nielsen, Kurt Aagaard

    2006-01-01

    The authors present trends in Nordic action research. They ask critical questions in the development towards mode 2 and points out alternative roads for a scientific consolidation of action research and interactive research.......The authors present trends in Nordic action research. They ask critical questions in the development towards mode 2 and points out alternative roads for a scientific consolidation of action research and interactive research....

  1. Researcher Positioning

    DEFF Research Database (Denmark)

    Khawaja, Iram; Mørck, Line Lerche

    2009-01-01

    involvement by the researcher, which challenges traditional perspectives onresearch and researcher positioning. A key point in this regard is the importance ofconstant awareness of and reflection on the multiple ways in which one's positioningas a researcher influences the research process. Studying the other...

  2. Single-center trials in neonatology: Issues to consider.

    Science.gov (United States)

    Sinha, Ian P; Sinha, Sunil K

    2015-12-01

    Single-center randomized controlled trials confer certain advantages over multi-center trials, in that they are cheaper and easier to design and conduct. However, recent research suggests that single-center trials are likely to overestimate treatment effects. There are notable examples in neonatology where results from multi-center trials have contradicted results of single-center studies. In this paper we discuss issues around external generalizability of single-center studies, and methodological issues that may cause bias. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. International Journal of Health Research

    African Journals Online (AJOL)

    Erah

    2009-12-29

    Dec 29, 2009 ... The journal welcomes original research papers, reviews and case reports on current topics of special interest and relevance ... manuscripts should normally be 10,000 words (20 single-spaced typewritten pages) for review, 6,000 words for research .... animals were determined as per OECD guidelines 425.

  4. Advances in single chain technology.

    Science.gov (United States)

    Gonzalez-Burgos, Marina; Latorre-Sanchez, Alejandro; Pomposo, José A

    2015-10-07

    The recent ability to manipulate and visualize single atoms at atomic level has given rise to modern bottom-up nanotechnology. Similar exquisite degree of control at the individual polymeric chain level for producing functional soft nanoentities is expected to become a reality in the next few years through the full development of so-called "single chain technology". Ultra-small unimolecular soft nano-objects endowed with useful, autonomous and smart functions are the expected, long-term valuable output of single chain technology. This review covers the recent advances in single chain technology for the construction of soft nano-objects via chain compaction, with an emphasis in dynamic, letter-shaped and compositionally unsymmetrical single rings, complex multi-ring systems, single chain nanoparticles, tadpoles, dumbbells and hairpins, as well as the potential end-use applications of individual soft nano-objects endowed with useful functions in catalysis, sensing, drug delivery and other uses.

  5. Nanodiamond Emitters of Single Photons

    Directory of Open Access Journals (Sweden)

    Vlasov I.I.

    2015-01-01

    Full Text Available Luminescence properties of single color centers were studied in nanodiamonds of different origin. It was found that single photon emitters could be realized even in molecularsized diamond (less than 2 nm capable of housing stable luminescent center “silicon-vacancy.” First results on incorporation of single-photon emitters based on luminescent nanodiamonds in plasmonic nanoantennas to enhance the photon count rate and directionality, diminish the fluorescence decay time, and provide polarization selectivity are presented.

  6. Settling for less out of fear of being single.

    Science.gov (United States)

    Spielmann, Stephanie S; MacDonald, Geoff; Maxwell, Jessica A; Joel, Samantha; Peragine, Diana; Muise, Amy; Impett, Emily A

    2013-12-01

    The present research demonstrates that fear of being single predicts settling for less in romantic relationships, even accounting for constructs typically examined in relationship research such as anxious attachment. Study 1 explored the content of people's thoughts about being single. Studies 2A and 2B involved the development and validation of the Fear of Being Single Scale. Study 2C provided preliminary support for the hypothesis that fear of being single predicts settling for less in ongoing relationships, as evidenced by greater dependence in unsatisfying relationships. Study 3 replicated this effect in a longitudinal study demonstrating that fear of being single predicts lower likelihood of initiating the dissolution of a less satisfying relationship. Studies 4A and 4B explored the predictive ability of fear of being single for self-reported dating standards. Across both samples, fear of being single was unrelated to self-reported standards for a mate, with the exception of consistently higher standards for parenting. Studies 5 and 6 explored romantic interest in targets that were manipulated to vary in responsiveness and physical attractiveness. These studies found that fear of being single consistently predicted romantic interest in less responsive and less attractive dating targets. Study 7 explored fear of being single during a speed-dating event. We found that fear of being single predicted being less selective in expressing romantic interest but did not predict other daters' romantic interest. Taken together, the present research suggests that fear of being single is a meaningful predictor of settling for less in relationships. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  7. Single quantum dots fundamentals, applications, and new concepts

    CERN Document Server

    2003-01-01

    This book reviews recent advances in the exciting and rapid growing field of semiconductor quantum dots by contributions from some of the most prominent researchers in the field. Special focus is given to the optical and electronic properties of single quantum dots due to their potential applications in devices operating with single electrons and/or single photons. This includes quantum dots in electric and magnetic fields, cavity-quantum electrodynamics, nonclassical light generation, and coherent optical control of excitons. Single Quantum Dots also addresses various growth techniques as well as potential device applications such as quantum dot lasers, and new concepts like a single-photon source, and a single quantum dot laser.

  8. Control of Single-Stage Single-Phase PV inverter

    DEFF Research Database (Denmark)

    Ciobotaru, Mihai; Teodorescu, Remus; Blaabjerg, Frede

    2005-01-01

    In this paper the issue of control strategies for single-stage photovoltaic (PV) inverter is addressed. Two different current controllers have been implemented and an experimental comparison between them has been made. A complete control structure for the single-phase PV system is also presented...

  9. A single sensor and single actuator approach to performance tailoring over a prescribed frequency band.

    Science.gov (United States)

    Wang, Jiqiang

    2016-03-01

    Restricted sensing and actuation control represents an important area of research that has been overlooked in most of the design methodologies. In many practical control engineering problems, it is necessitated to implement the design through a single sensor and single actuator for multivariate performance variables. In this paper, a novel approach is proposed for the solution to the single sensor and single actuator control problem where performance over any prescribed frequency band can also be tailored. The results are obtained for the broad band control design based on the formulation for discrete frequency control. It is shown that the single sensor and single actuator control problem over a frequency band can be cast into a Nevanlinna-Pick interpolation problem. An optimal controller can then be obtained via the convex optimization over LMIs. Even remarkable is that robustness issues can also be tackled in this framework. A numerical example is provided for the broad band attenuation of rotor blade vibration to illustrate the proposed design procedures. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

  10. Do single women value early retirement more than single men?

    DEFF Research Database (Denmark)

    Danø, Anne Møller; Ejrnæs, Mette; Husted, Leif

    2005-01-01

    The focus of this paper is to analyse why a large fraction of single elderly people choose to retire early. A structural model directly based on the individual decision of labour supply is estimated on a sample of singles, where singles are defined as those who are living alone. We find that inco...... are willing to reduce the income to 81%. Men's retirement decision is mainly influenced by income and health, whereas women's retirement decision is also affected by education and unemployment experience...... and health are important determinants of the retirement decision. Furthermore, we find substantial gender differences in the retirement pattern. Healthy single women value retirement more than healthy single men and are willing to reduce their disposable income to 74% of their previous income while men...

  11. Ranking Baltic States Researchers

    Directory of Open Access Journals (Sweden)

    Gyula Mester

    2017-10-01

    Full Text Available In this article, using the h-index and the total number of citations, the best 10 Lithuanian, Latvian and Estonian researchers from several disciplines are ranked. The list may be formed based on the h-index and the total number of citations, given in Web of Science, Scopus, Publish or Perish Program and Google Scholar database. Data for the first 10 researchers are presented. Google Scholar is the most complete. Therefore, to define a single indicator, h-index calculated by Google Scholar may be a good and simple one. The author chooses the Google Scholar database as it is the broadest one.

  12. Research Design

    DEFF Research Database (Denmark)

    2019-01-01

    Gunnar Scott Reinbacher (editor) Antology.  Research Design : Validation in Social Sciences. Gunnar Scott Reinbacher: Introduction. Research design and validity. 15p Ole Riis: Creative Research design. 16 p Lennart Nørreklit: Validity in Research Design. 24p Gitte Sommer Harrits: Praxeological...... Scott Reinbacher: Multidisciplinary Research Designs in Problem Based Research. The case of an european project on chronical diseases, the Tandem project (Training Alternmative Networking Skills in Diabetes Management). 15p Niels Nørgaard Kristensen: A qualitative bottom up approach to post modern...... knowledge: An integrated strategy for combining "explaining" and "understanding". 22p Heidi Houlberg Salomonsen & Viola Burau: Comparative research designs. 40p Rasmus Antoft & Heidi Houlberg Salomonsen: Studying organizations by a Pragmatic Research Design: the case of qualitative case study  designs. 31p...

  13. Research circles

    DEFF Research Database (Denmark)

    Nordentoft, Helle Merete; Thomsen, Rie; Möller, Jonas

    lifelong guidance policies. This paper presents `research circles´ as a way to develop guidance practices through long-term research relationships between practice and research. Research circles support a bottom up approach to policy development just like ELGPN considers to be necessary and required...... in career guidance development. In the paper we draw on the preliminary findings from an ongoing Nordic project: “The future of career guidance and educational counselling”. Specifically, we explore the career guidance practitioners´ response to research circles as means to professional development. We...... argue that this practicebased way of organizing research facilitates learning, and potentially, qualifies practice. The collaboration between researchers and practitioners in the research circle fosters a joint venture and an academic perspective on practice, which stimulates practitioners to step out...

  14. Research Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Martens, Frederick H. [Argonne National Laboratory; Jacobson, Norman H.

    1968-09-01

    This booklet discusses research reactors - reactors designed to provide a source of neutrons and/or gamma radiation for research, or to aid in the investigation of the effects of radiation on any type of material.

  15. Quantum optics with single quantum dot devices

    International Nuclear Information System (INIS)

    Zwiller, Valery; Aichele, Thomas; Benson, Oliver

    2004-01-01

    A single radiative transition in a single-quantum emitter results in the emission of a single photon. Single quantum dots are single-quantum emitters with all the requirements to generate single photons at visible and near-infrared wavelengths. It is also possible to generate more than single photons with single quantum dots. In this paper we show that single quantum dots can be used to generate non-classical states of light, from single photons to photon triplets. Advanced solid state structures can be fabricated with single quantum dots as their active region. We also show results obtained on devices based on single quantum dots

  16. [Genealogical Research.

    Science.gov (United States)

    McClure, Patricia Harlan

    Two Institute papers were concerned with genealogical research. "Manuscripts, Private Papers and Genealogical Research," deals with the handling and evaluation of unpublished and private papers in genealogical research. "The Genealogical Society of the Church of Jesus Christ of the Latter-Day Saints," discusses the Mormon…

  17. Single-cavity SLED device

    International Nuclear Information System (INIS)

    Lippmann, B.A.

    1984-09-01

    The conventional SLED device used at SLAC requires two cavities. However, the same effect can be obtained with a single cavity; the theory and operation of the device is the same, only the hardware is changed. The single-cavity device is described here

  18. Single top t-channel

    CERN Document Server

    Faltermann, Nils

    2017-01-01

    The production of single top quarks allows to study the interplay of top quark physics and the electroweak sector of the standard model. Deviations from predictions can be a hint for physics beyond the standard model. The t-channel is the dominant production mode for single top quarks at the LHC. This talk presents the latest measurements from the ATLAS and CMS collaborations.

  19. Quantum transport through single molecules

    NARCIS (Netherlands)

    Osorio Oliveros, E.A.

    2009-01-01

    This thesis describes three-terminal transport measurements through single molecules. The interest in this field stems from the dream that single molecules will form the building blocks for future nanoscale electronic devices. The advantages are their small size -nanometers-, and their synthetic

  20. Editorial -Research! Research! Research! What are Thou?

    Directory of Open Access Journals (Sweden)

    Ashok Shyam

    2013-04-01

    Full Text Available Being in field of Orthopaedic research since last 6 years, I have personally been witness to the rapid change in landscape of Othopaedic Research and also medical research in general. The sheer volumes of publications is overwhelming to the extent of being mostly ineffective in providing significant positive addition to the current literature. “There are too many variables” is one of my favorite phrase when I start to explain something to myself. Looking at as many variables as we can think of, makes us understand concepts within the limitations of given variables. Something similar to Ashby’s law that we spoke about in last Editorial [1]. However when we try to apply this to word ‘Research’ the amount of subjective stereotype that is associated with the word defeats all attempt to decipher and communicate clearly. Originally word Research derived from French ‘Researche’ simply means ‘Pursuit of Knowledge’. We as medical practitioners in search of better treatment for our patients are always in pursuit of knowledge. This knowledge is mostly build individually and is learned from individual experience and learning. This is a subjective body of knowledge and this is what makes one surgeon better than another. But is this ‘Research’? Yes it is Research and it serves the main purpose of medical research that is to improve the treatment given to patients. However this is a limited form of research, limited by individual’s ability and capacity. It also does not subject itself to rigorous ‘scientific methods’ and may not be acceptable to a community of ‘Modern Researchers’. Another form of Research of pursuit of knowledge is again from the clinics and from reading journals and books. A collaboration of clinical experience and written word adds a more thoughtful way of pursuing knowledge. This I think is the way majority of medical practitioners acquire knowledge. This keeps them updated and also helps them provide good

  1. Research misconduct

    International Nuclear Information System (INIS)

    Gilbert, F.J.; Denison, A.R.

    2003-01-01

    Good research practice is important to the scientific community. An awareness of what constitutes poor practice is important. Various types of research misconduct are defined in this article. The extent of research misconduct in the field of radiology has been assessed by contacting five English language radiology journals. Redundant or duplicate publication has been reported infrequently, Radiology (1), American Journal of Roentgenology (3), Clinical Radiology (3), British Journal of Radiology (2) and European Radiology (1). The issue of how the radiology community might tackle research misconduct is discussed with reference to guidance from the Medical Research Council, the Wellcome Trust and the Committee of Publication Ethics

  2. Descriptive Research

    DEFF Research Database (Denmark)

    Wigram, Anthony Lewis

    2003-01-01

    Descriptive research is described by Lathom-Radocy and Radocy (1995) to include Survey research, ex post facto research, case studies and developmental studies. Descriptive research also includes a review of the literature in order to provide both quantitative and qualitative evidence of the effect...... starts will allow effect size calculations to be made in order to evaluate effect over time. Given the difficulties in undertaking controlled experimental studies in the creative arts therapies, descriptive research methods offer a way of quantifying effect through descriptive statistical analysis...

  3. Research Article

    Indian Academy of Sciences (India)

    a

    Some studies have shown that 157 genes are associated with key pathways in the pituitary of developmental stages (Brinkmeier et al. 2009), and 222 microRNAs (miRNAs) have been identified from pituitary glands and may affect postnatal growth of pigs (Ye et al. 2015). MiRNAs are a class of single-stranded endogenous ...

  4. Research Article

    African Journals Online (AJOL)

    2017-09-01

    Sep 1, 2017 ... conservation agriculture because it helps preserve soil nutrients, water absorption enhancing and infiltration and .... SD treatment, soil structure is preserved following a single direct sowing pass. By cons, in .... Agricultural production is the interaction of various factors and soil is a natural resource.

  5. Single-dopant resonance in a single-electron transistor

    Science.gov (United States)

    Golovach, V. N.; Jehl, X.; Houzet, M.; Pierre, M.; Roche, B.; Sanquer, M.; Glazman, L. I.

    2011-02-01

    Single dopants in semiconductor nanostructures have been studied in great detail recently as they are good candidates for quantum bits, provided they are coupled to a detector. Here we report the coupling of a single As donor atom to a single-electron transistor (SET) in a silicon nanowire field-effect transistor. Both capacitive and tunnel coupling are achieved, the latter resulting in a dramatic increase of the conductance through the SET, by up to one order of magnitude. The experimental results are well explained by the rate-equation theory developed in parallel with the experiment.

  6. Research ethics for clinical researchers.

    Science.gov (United States)

    Harnett, John D; Neuman, Richard

    2015-01-01

    This chapter describes the history of the development of modern research ethics. The governance of research ethics is discussed and varies according to geographical location. However, the guidelines used for research ethics review are very similar across a wide variety of jurisdictions. The paramount importance of protecting the privacy and confidentiality of research participants is discussed at length. Particular emphasis is placed on the process of informed consent, and step-by-step practical guidelines are described. The issue of research in vulnerable populations is touched upon and guidelines are provided. Practical advice is provided for researchers to guide their interactions with research ethics boards. Issues related to scientific misconduct and research fraud are not dealt with in this paper.

  7. Research Review: Doing Artistic Research

    Science.gov (United States)

    Serig, Dan

    2012-01-01

    In this review, the author focuses on the pragmatic consideration: How do artists do artistic research? Artistic research in the context of this review is about the connections and relationships among three primary domains: (1) the arts; (2) higher education; and (3) arts education. Broadly stated, all artists do research when they do art--whether…

  8. Research Impact and Educational Research

    Science.gov (United States)

    Oancea, Alis

    2013-01-01

    Based on a 2010-11 study involving senior researchers from seven disciplines, this article explores critically some of the diverse interpretations of impact in different disciplines, sub-fields and modes of research, and researchers' views about how these interpretations articulate with top-down impact agendas and with university structures…

  9. Is operations research really research?

    African Journals Online (AJOL)

    Science [23], is concerned with man-made, artificial phenomena. 2.3 Types of research. If one reads almost any book ... may be considered basic research if the practical application is only potential. 3.2 Practice of operations research .... academics to supplement their salaries. For these academics it is of great advantage if.

  10. Research management and research output

    Directory of Open Access Journals (Sweden)

    Anita Bosch

    2011-12-01

    Full Text Available Purpose: A study was conducted at two merged South African higher education institutions to determine which management factors, as identified in a literature study as well as through a factor analysis of survey data, were predictive of the dependent variable 'research output'. Problem investigated: Research output contributes to creating sustainability of knowledge of management sciences and therefore the active management of research is in the interest of progressive universities. Research management related activities are usually associated with measurable targets, detailed plans, rigorous evaluation and decisive action - all of which are observable (perhaps programmable behaviour also referred to as tangible factors. Authors argue that the tangible factors of any successful institution can be copied, technology can be bought, and in theory you should have an instantly thriving research institution. It is, however, clear that although many institutions have exactly the same technology and structure as their successful competitors, they still fail to succeed in increasing research output. Design and Research methodology or approach: A survey was distributed to n=411 and yielded a 49.6% response rate. A confirmatory reliability analysis as well as a factor analysis was conducted. Findings/implications: The empirical model that was derived through a factor analysis strengthens the argument that both tangible and intangible factors exist in a research environment. Tangible and intangible factors play a different role in predicting research output. The tangible factors are predictors of research output for non-research-active academics. The theoretical research output prediction model highlights predictors such as 'professional activities' and 'individual skills and competence' for specific groupings. The theoretical model indicates that the factors that predict research output are largely intrinsic to a researcher but could also be supported by

  11. Single banking supervision and the single supervisory mechanism

    Directory of Open Access Journals (Sweden)

    Gheorghe, C. A.

    2013-06-01

    Full Text Available A resolution seems to have been found for the banking crisis. The first steps have been made towards the construction of the Economic and Monetary Union, steps involving the single supervision of banks, in order to avoid the discount of a new financial crisis on the expense of the EU state members. The Single Supervisory Mechanism – SSM is to become effective as of March 1, 2014, at the earliest.

  12. READING STATISTICS AND RESEARCH

    Directory of Open Access Journals (Sweden)

    Reviewed by Yavuz Akbulut

    2008-10-01

    Full Text Available The book demonstrates the best and most conservative ways to decipher and critique research reports particularly for social science researchers. In addition, new editions of the book are always better organized, effectively structured and meticulously updated in line with the developments in the field of research statistics. Even the most trivial issues are revisited and updated in new editions. For instance, purchaser of the previous editions might check the interpretation of skewness and kurtosis indices in the third edition (p. 34 and in the fifth edition (p.29 to see how the author revisits every single detail. Theory and practice always go hand in hand in all editions of the book. Re-reading previous editions (e.g. third edition before reading the fifth edition gives the impression that the author never stops ameliorating his instructional text writing methods. In brief, “Reading Statistics and Research” is among the best sources showing research consumers how to understand and critically assess the statistical information and research results contained in technical research reports. In this respect, the review written by Mirko Savić in Panoeconomicus (2008, 2, pp. 249-252 will help the readers to get a more detailed overview of each chapters. I cordially urge the beginning researchers to pick a highlighter to conduct a detailed reading with the book. A thorough reading of the source will make the researchers quite selective in appreciating the harmony between the data analysis, results and discussion sections of typical journal articles. If interested, beginning researchers might begin with this book to grasp the basics of research statistics, and prop up their critical research reading skills with some statistics package applications through the help of Dr. Andy Field’s book, Discovering Statistics using SPSS (second edition published by Sage in 2005.

  13. Operational Research

    CERN Document Server

    Almeida, João; Oliveira, José; Pinto, Alberto

    2018-01-01

    This proceedings book presents selected contributions from the XVIII Congress of APDIO (the Portuguese Association of Operational Research) held in Valença on June 28–30, 2017. Prepared by leading Portuguese and international researchers in the field of operations research, it covers a wide range of complex real-world applications of operations research methods using recent theoretical techniques, in order to narrow the gap between academic research and practical applications. Of particular interest are the applications of, nonlinear and mixed-integer programming, data envelopment analysis, clustering techniques, hybrid heuristics, supply chain management, and lot sizing and job scheduling problems. In most chapters, the problems, methods and methodologies described are complemented by supporting figures, tables and algorithms.   The XVIII Congress of APDIO marked the 18th installment of the regular biannual meetings of APDIO – the Portuguese Association of Operational Research. The meetings bring toget...

  14. Researcher positioning

    DEFF Research Database (Denmark)

    Mørck, Line Lerche; Khawaja, Iram

    2009-01-01

    abstract  This article focuses on the complex and multi-layered process of researcher positioning, specifically in relation to the politically sensitive study of marginalised and ‘othered' groups such as Muslims living in Denmark. We discuss the impact of different ethnic, religious and racial...... backgrounds, of membership in a minoritised[i] or majoritised group, and the influence of different theoretical and methodological outlooks on our common goal of trying to transcend existing othering and objectifying representations of Muslims in Western societies. This process sometimes entails a direct...... political and personal involvement by the researcher, which challenges traditional perspectives on research and researcher positioning. A key point in this regard is the importance of constant awareness of and reflection on the multiple ways in which one's positioning as a researcher influences the research...

  15. Immunome Research

    Science.gov (United States)

    Petrovsky, Nikolai

    2005-01-01

    Immunology research has been transformed in the post-genomics era, with high throughput molecular biology and information technologies taking an increasingly central role. This has led to the development of a new area of science termed "Immunomics", that encompasses genomic, high throughput and bioinformatic approaches to immunology. In recognition of the increasing importance of this field, Immunome Research is a new Open Access, online journal, that will publish cutting edge research across the field of Immunomics. Immunome Research will publish a wide range of article types including specialty immunology databases, immunology database tools, immunome epitope research, epitope analysis tools, high-throughput technologies (gene sequencing, microarrays, proteomics), white papers, mathematical and theoretical models, and prediction tools. Immunome Research is the official journal of the International Immunomics Society (IIMMS). PMID:16305754

  16. Centering research

    DEFF Research Database (Denmark)

    Katan, Lina Hauge; Baarts, Charlotte

    idea, insofar as the ways students read and write need altering to correspond to the practice of research and prepare students accordingly. In the paper, we discuss therefore the possible challenges of grounding research-based teaching in reading, thinking and writing, as indicated by our empirical......’ exercises tend to dominate the common understandings of research-based learning. Here we address a specific area of inquiry overlooked by previous studies: whether and how reading, thinking and writing indeed share the same learning potentials as the practical foundation for research-based teaching....... In the humanities and social sciences, integrated acts of reading, writing and thinking account for an obvious and substantial overlap in student and researcher practices, creating a clear opportunity for research-based teaching. Moreover, our empirical data point to reading, thinking and writing as quintessential...

  17. Research methodology

    DEFF Research Database (Denmark)

    Kuada, John

    This book deals with how students should use of research methods in their university projects. It aims at helping students in developing comprehensive research strategies for their projects. It also provides introduction to issues of philosophy of science as applied in the social sciences....... That is it provides them with a fair understanding of the root assumptions that guide researchers in their investigations and how these assumptions inform their theoretical thinking and choice of methods....

  18. Research Review

    OpenAIRE

    Anonymous

    1981-01-01

    Research Reviewed: "Global Modeling After Its First Decade"; "Monthly Food Price Forecasts"; "Costs of Marketing Slaughter Cattle: Computerized versus Conventional Auction Systems"; "Survival Strategies for Agricultural Cooperatives"

  19. Plant Research

    Science.gov (United States)

    1990-01-01

    The Land's agricultural research team is testing new ways to sustain life in space as a research participant with Kennedy Space Center's Controlled Ecological Life Support System (CELSS). The Land, sponsored by Kraft General Foods, is an entertainment, research, and education facility at EPCOT Center, part of Walt Disney World. The cooperative effort is simultaneously a research and development program, a technology demonstration that provides the public to see high technology at work and an area of potential spinoff: the CELSS work may generate Earth use technology beneficial to the hydroponic (soilless growing) vegetable production industries of the world.

  20. Animal research

    DEFF Research Database (Denmark)

    Olsson, I.A.S.; Sandøe, Peter

    2012-01-01

    in research is analyzed from the viewpoint of three distinct ethical approaches: contractarianism, utilitarianism, and animal rights view. On a contractarian view, research on animals is only an ethical issue to the extent that other humans as parties to the social contract care about how research animals...... are faring. From the utilitarian perspective, the use of sentient animals in research that may harm them is an ethical issue, but harm done to animals can be balanced by benefit generated for humans and other animals. The animal rights view, when thoroughgoing, is abolitionist as regards the use of animals...

  1. Clinical Research

    DEFF Research Database (Denmark)

    Christensen, Irene

    2016-01-01

    This paper is about the logic of problem solving and the production of scientific knowledge through the utilisation of clinical research perspective. Ramp-up effectiveness, productivity, efficiency and organizational excellence are topics that continue to engage research and will continue doing so...... for years to come. This paper seeks to provide insights into ramp-up management studies through providing an agenda for conducting collaborative clinical research and extend this area by proposing how clinical research could be designed and executed in the Ramp- up management setting....

  2. Letterform research

    DEFF Research Database (Denmark)

    Beier, Sofie

    2016-01-01

    This paper looks into the history of letterform research and discusses why the discipline has yet to make the big break within design research. By highlighting two of the most popular focus areas (letter distinctiveness and the role of serifs) and by discussing various forms of methodological...... shortcomings, the paper suggests that future research into letterforms should (1) draw on results from the field of reading research (2) be based on test material informed by design knowledge and (3) move away from the former tendency of looking for universal answers....

  3. Researching experiences

    DEFF Research Database (Denmark)

    Gjedde, Lisa; Ingemann, Bruno

    , dialogue, moods, values and narratives have been investigated qualitatively with more than sixty informants in a range of projects. The processual methodological insights are put into a theoretical perspective and also presented as pragmatic dilemmas. Researching Experiences is relevant not only...... for students and researchers in media and communication studies but also for practitioners within the fields of media, communication and experience design....... for researching experiences in a variety of settings ranging from the museum, to news photography, and interactive media. The research led to the development of a set of methodological tools and approaches we term the reflexivity lab. The interaction in the experimental situation between the media and body...

  4. Getting Value from Research

    Science.gov (United States)

    Duke, Charles

    2004-03-01

    During the past decade the environment for and execution of industrial research has changed profoundly, as recently documented in Robert Buderi, Engines of Tomorrow (Simon and Shuster, New York, 2000). The vertically integrated single-firm research-through-product value chains of the twentieth century are gone, replaced by value chains the various elements of which can come from different firms in different parts of the world as described, e.g., by Henry W. Cheesbrough, Open Innovation (Harvard Business School Press, Boston, 2003). The consequences of this change are profound for national R policy, the R strategies of specific firms, and individual researchers. (See e.g., C. B. Duke, How to get value from R, Physics World, 17 (August 1997), 17.) In this presentation I sketch the strategies that firms employ to generate value from their research. Then I discuss the ingredients that are required to implement these strategies by creating value chains to deliver the fruits of research to customers. I indicate how the role of physical sciences is changing as unique hardware, based on advanced research in the physical sciences, becomes an increasingly minor (and often outsourced) component of integrated systems offerings. I close by noting implications of these developments on the nature of the careers that physicists can expect in industry and on the skills and cultural attributes that are required to be successful in the new industrial research environment.

  5. PREFACE: 3rd International Conference of Mechanical Engineering Research (ICMER 2015)

    Science.gov (United States)

    Mamat, Riazalman; Rahman, Mustafizur; Mohd. Zuki Nik Mohamed, Nik; Che Ghani, Saiful Anwar; Harun, Wan Sharuzi Wan

    2015-12-01

    disseminate research in all fields of mechanical engineering. Topics cover synthesis, applications, and fundamental studies of the topics related to mechanical engineering. In addition, booths for industries to showcase their state-of-the-art products are also provided. The organizing committee of the conference thanks all the participants for their fruitful work and personal contribution to the development of these conference proceedings.

  6. Single-electron thermal noise.

    Science.gov (United States)

    Nishiguchi, Katsuhiko; Ono, Yukinori; Fujiwara, Akira

    2014-07-11

    We report the observation of thermal noise in the motion of single electrons in an ultimately small dynamic random access memory (DRAM). The nanometer-scale transistors that compose the DRAM resolve the thermal noise in single-electron motion. A complete set of fundamental tests conducted on this single-electron thermal noise shows that the noise perfectly follows all the aspects predicted by statistical mechanics, which include the occupation probability, the law of equipartition, a detailed balance, and the law of kT/C. In addition, the counting statistics on the directional motion (i.e., the current) of the single-electron thermal noise indicate that the individual electron motion follows the Poisson process, as it does in shot noise.

  7. Single-employer Pension Plans

    Data.gov (United States)

    Pension Benefit Guaranty Corporation — This spreadsheet lists the active single-employer pensions plans insured by PBGC. Plans are identified by name, employer identification number (EIN) and plan number...

  8. Single Sign On Internal (SSOi)

    Data.gov (United States)

    Department of Veterans Affairs — Provides single sign-on solution for internal facing VA applications. Allows internal users access to a variety of VA systems and applications using a reduced set of...

  9. Generalization from Single Cases and the Concept of Double Dialogicality

    DEFF Research Database (Denmark)

    Demuth, Carolin

    2017-01-01

    The present paper addresses how the concept of double-dialogicality may contribute to our understanding of how to generalize from single cases. Various attempts have been made within qualitative social research to define how generalization is possible from single cases. One problem with generaliz......The present paper addresses how the concept of double-dialogicality may contribute to our understanding of how to generalize from single cases. Various attempts have been made within qualitative social research to define how generalization is possible from single cases. One problem...... in this. In social interactions, persons draw on culturally available resources without which communicative meaning would be impossible. Double dialogicality as introduced by Per Linell helps to understand this relation and allows for identifying the general in the unique....

  10. Systems interaction and single failure criterion

    International Nuclear Information System (INIS)

    1981-01-01

    This report documents the results of a six-month study to evaluate the ongoing research programs of the U.S. Nuclear Regulatory Commission (NRC) and U.S. commercial nuclear station owners which address the safety significance of systems interaction and the regulatory adequacy of the single failure criterion. The evaluation of system interactions provided is the initial phase of a more detailed study leading to the development and application of methodology for quantifying the relative safety of operating nuclear plants. (Auth.)

  11. Future in psychopathology research.

    Science.gov (United States)

    Heckers, Stephan

    2014-03-01

    Psychopathology research has focused either on the analysis of the mental state in the here and now or on the synthesis of mental status abnormalities with biological markers and outcome data. These two schools of psychopathology, the analytic and the synthetic, make contrasting assumptions, take different approaches, and pursue divergent goals. Analytic psychopathology favors the individual person and unique biography, whereas synthetic psychopathology abstracts from the single case and generalizes to the population level. The dimension of time, especially the prediction of future outcomes, is viewed differently by these two schools. Here I outline how Carpenter's proposal of strong inference and theory testing in psychopathology research can be used to test the value of analytic and synthetic psychopathology. The emerging field of personalized psychiatry can clarify the relevance of psychopathology for contemporary research in psychiatry.

  12. Research Ethics

    Science.gov (United States)

    Dooly, Melinda; Moore, Emilee; Vallejo, Claudia

    2017-01-01

    Qualitative research, especially studies in educational contexts, often brings up questions of ethics because the study design involves human subjects, some of whom are under age (e.g. data collected in primary education classrooms). It is not always easy for young researchers to anticipate where ethical issues might emerge while designing their…

  13. Research Review

    Science.gov (United States)

    Serig, Dan, Ed.

    2010-01-01

    This research review is dedicated to the memory of William Safire (1929-2009). A visionary leader, Safire brought other visionaries, researchers, educators, artists, and policymakers together to explore the confluence of arts education and neuroscience. He fostered the new field of neuroeducation in his work as chair of The Dana Foundation in…

  14. Research Review

    Science.gov (United States)

    Serig, Dan

    2011-01-01

    In this review, the author explores an often-used process in research--the mind map. He uses this method in his own research and artwork. He also uses this extensively with students, particularly master students when they are trying to surround issues in their thesis projects. Mind maps are closely associated with brainstorming, as brainstorming…

  15. Remote Research

    CERN Document Server

    Tulathimutte, Tony

    2011-01-01

    Remote studies allow you to recruit subjects quickly, cheaply, and immediately, and give you the opportunity to observe users as they behave naturally in their own environment. In Remote Research, Nate Bolt and Tony Tulathimutte teach you how to design and conduct remote research studies, top to bottom, with little more than a phone and a laptop.

  16. Research Article

    African Journals Online (AJOL)

    2016-06-18

    Jun 18, 2016 ... Published o. ABSTRACT. Recommender systems for research pape years more than 170 research papers,paten. Scientific papers recommender systemsare user which are consistent with the users' tastes and users behaviors.Since the volu recommender systemshave not the ability papers according to ...

  17. Allographic Agraphia for Single letters

    OpenAIRE

    Menichelli, Alina; Machetta, Francesca; Zadini, Antonella; Semenza, Carlo

    2012-01-01

    The case is reported of a patient (PS) who, following acute encephalitis with residual occipito-temporal damage, showed a selective deficit in writing cursive letters in isolation, but no difficulty to write cursive-case words and non-words. Notably, he was able to recognize the same allographs he could not write and to produce both single letters and words in print. In addition to this selective single letter writing difficulty, the patient demonstrated an inability to correctly perform a se...

  18. Single nanoparticle tracking spectroscopic microscope

    Science.gov (United States)

    Yang, Haw [Moraga, CA; Cang, Hu [Berkeley, CA; Xu, Cangshan [Berkeley, CA; Wong, Chung M [San Gabriel, CA

    2011-07-19

    A system that can maintain and track the position of a single nanoparticle in three dimensions for a prolonged period has been disclosed. The system allows for continuously imaging the particle to observe any interactions it may have. The system also enables the acquisition of real-time sequential spectroscopic information from the particle. The apparatus holds great promise in performing single molecule spectroscopy and imaging on a non-stationary target.

  19. Single--stranded DNA mycoplasmaviruses

    Energy Technology Data Exchange (ETDEWEB)

    Maniloff, J.; Das, J.; Nowak, J.A.

    1978-01-01

    Two general types of single--stranded DNA bacteriophases have been described, icosahedral virions (e.g., 0X174) and filamentous virions (e.g., M13). Mycoplasmavirus MVL51 appears to represent another type of single--stranded DNA phage, with a genome size close to that of 0X174 and a nonlytic mode of infection like that of filamentous phages. The bullet shaped MVL51 morphology is unlike that of other known phages.

  20. Analysis of single biological cells

    International Nuclear Information System (INIS)

    Watt, Frank

    2002-01-01

    The extraction of elemental information from single cultured cells using nuclear microscopy is an area of great potential because it can provide both quantitative information on the uptake of elements by the cell, and also its elemental response to a wide variety of external stimuli. A recent technique based on nuclear physics technology enables the analysis of single cells down to the parts per million level to be achieved

  1. Centering research

    DEFF Research Database (Denmark)

    Katan, Lina Hauge; Baarts, Charlotte

    ’ exercises tend to dominate the common understandings of research-based learning. Here we address a specific area of inquiry overlooked by previous studies: whether and how reading, thinking and writing indeed share the same learning potentials as the practical foundation for research-based teaching...... and collected 24 portfolios in which students reflect auto-ethnographically on their educational practices. Analyzing this qualitative material, we explore how researchers and students respectively read and write to develop and advance their thinking in those learning processes that the two groups fundamentally...... findings We then propose a set of experimentally designed curricular frameworks that have been shown to alter student engagement in reading and writing, encouraging their learning to become more research-like. Finally, we return to the literature on research-based teaching, asking how an emphasis...

  2. Design Research

    DEFF Research Database (Denmark)

    Design Research is a new interdisciplinary research area with a social science orientation at its heart, and this book explores how scientific knowledge can be put into practice in ways that are at once ethical, creative, helpful, and extraordinary in their results. In order to clarify the common...... aspects – in terms of features and approaches – that characterize all strands of research disciplines addressing design, Design Research undertakes an in depth exploration of the social processes involved in doing design, as well as analyses of the contexts for design use. The book further elicits...... ‘synergies from interdisciplinary perspectives’ by discussing and elaborating on differing academic perspectives, theoretical backgrounds, and design concept definitions, and evaluating their unique contribution to a general core of design research. This book is an exciting contribution to this little...

  3. Research report

    International Nuclear Information System (INIS)

    Whitley, J.E.

    1990-07-01

    The SURRC (Scottish Universities Research and Reactor Centre) is a multidisciplinary research centre shared by a consortium of Scottish Universities. Funding is jointly by the University Funding Committee and commercially from Research Councils, government departments and industry. The focus of research lies in earth, environmental and biomedical sciences. The research activities are discussed under the following headings: environmental radioactivity and nuclear geochemistry, neutron activation analysis, inductively coupled plasma-mass spectrometry, body composition studies, stable isotopes in biological sciences, nuclear physics, luminescence dating and dosimetry radiation effects in electrical insulation, gamma-ray irradiation processing, radiogenic isotopes in geology, stable isotope geology, laser microprobe mass spectrometry for geology and NERC Radiocarbon Laboratory work. There are also reports on the reactor itself; reactor operation, production of radioactive isotopes and application of radioactive tracers. The educational aspects of the Centre, safety aspects, staffing, funding and all publications are reported. (UK)

  4. Survey research.

    Science.gov (United States)

    Alderman, Amy K; Salem, Barbara

    2010-10-01

    Survey research is a unique methodology that can provide insight into individuals' perspectives and experiences and can be collected on a large population-based sample. Specifically, in plastic surgery, survey research can provide patients and providers with accurate and reproducible information to assist with medical decision-making. When using survey methods in research, researchers should develop a conceptual model that explains the relationships of the independent and dependent variables. The items of the survey are of primary importance. Collected data are only useful if they accurately measure the concepts of interest. In addition, administration of the survey must follow basic principles to ensure an adequate response rate and representation of the intended target sample. In this article, the authors review some general concepts important for successful survey research and discuss the many advantages this methodology has for obtaining limitless amounts of valuable information.

  5. Microfluidics-Enabled Enzyme Activity Measurement in Single Cells.

    Science.gov (United States)

    Tesauro, Cinzia; Frøhlich, Rikke; Stougaard, Magnus; Ho, Yi-Ping; Knudsen, Birgitta R

    2015-01-01

    Cellular heterogeneity has presented a significant challenge in the studies of biology. While most of our understanding is based on the analysis of ensemble average, individual cells may process information and respond to perturbations very differently. Presented here is a highly sensitive platform capable of measuring enzymatic activity at the single-cell level. The strategy innovatively combines a rolling circle-enhanced enzyme activity detection (REEAD) assay with droplet microfluidics. The single-molecule sensitivity of REEAD allows highly sensitive detection of enzymatic activities, i.e. at the single catalytic event level, whereas the microfluidics enables isolation of single cells. Further, confined reactions in picoliter-sized droplets significantly improve enzyme extraction from human cells or microorganisms and result in faster reaction kinetics. Taken together, the described protocol is expected to open up new possibilities in the single-cell research, particularly for the elucidation of heterogeneity in a population of cells.

  6. Research reactors

    International Nuclear Information System (INIS)

    Merchie, Francois

    2015-10-01

    This article proposes an overview of research reactors, i.e. nuclear reactors of less than 100 MW. Generally, these reactors are used as neutron generators for basic research in matter sciences and for technological research as a support to power reactors. The author proposes an overview of the general design of research reactors in terms of core size, of number of fissions, of neutron flow, of neutron space distribution. He outlines that this design is a compromise between a compact enough core, a sufficient experiment volume, and high enough power densities without affecting neutron performance or its experimental use. The author evokes the safety framework (same regulations as for power reactors, more constraining measures after Fukushima, international bodies). He presents the main characteristics and operation of the two families which represent almost all research reactors; firstly, heavy water reactors (photos, drawings and figures illustrate different examples); and secondly light water moderated and cooled reactors with a distinction between open core pool reactors like Melusine and Triton, pool reactors with containment, experimental fast breeder reactors (Rapsodie, the Russian BOR 60, the Chinese CEFR). The author describes the main uses of research reactors: basic research, applied and technological research, safety tests, production of radio-isotopes for medicine and industry, analysis of elements present under the form of traces at very low concentrations, non destructive testing, doping of silicon mono-crystalline ingots. The author then discusses the relationship between research reactors and non proliferation, and finally evokes perspectives (decrease of the number of research reactors in the world, the Jules Horowitz project)

  7. Learning From Others About Research Evidence (editorial

    Directory of Open Access Journals (Sweden)

    Alison Brettle

    2012-06-01

    .The unsuitability of the RCT has also been raised regarding generating evidence for EBLIP (e.g. Banks, 2008; however, “best evidence” doesn’t need to be an RCT. The definition of EBLIP provided by Booth (2006 mentions best quality evidence (generated from research, among other elements, but makes no mention of particular research designs. In addition, both Eldredge (2004 and Crumley and Koufogiannakis (2002 have argued for the consideration of a wide type of study designs as evidence within EBLIP, a viewpoint with which I have long agreed. After all, it is much more important to choose a design that is suitable to answer the question at hand and provide good quality evidence, rather than trying to use a "good quality" design at the expense of finding relevant evidence. Bearing that in mind, I'm racking my brains to think of how I can use webometrics and techniques from history to investigate my practice. At the same time, I urge you to think widely about research evidence and try exploring some different methodologies and see what evidence they can reveal.

  8. Czochralski method of growing single crystals. State-of-art

    International Nuclear Information System (INIS)

    Bukowski, A.; Zabierowski, P.

    1999-01-01

    Modern Czochralski method of single crystal growing has been described. The example of Czochralski process is given. The advantages that caused the rapid progress of the method have been presented. The method limitations that motivated the further research and new solutions are also presented. As the example two different ways of the technique development has been described: silicon single crystals growth in the magnetic field; continuous liquid feed of silicon crystals growth. (author)

  9. Single particle tomography in EMAN2.

    Science.gov (United States)

    Galaz-Montoya, Jesús G; Flanagan, John; Schmid, Michael F; Ludtke, Steven J

    2015-06-01

    Single particle tomography (SPT or subtomogram averaging) offers a powerful alternative to traditional 2-D single particle reconstruction for studying conformationally or compositionally heterogeneous macromolecules. It can also provide direct observation (without labeling or staining) of complexes inside cells at nanometer resolution. The development of computational methods and tools for SPT remains an area of active research. Here we present the EMAN2.1 SPT toolbox, which offers a full SPT processing pipeline, from particle picking to post-alignment analysis of subtomogram averages, automating most steps. Different algorithm combinations can be applied at each step, providing versatility and allowing for procedural cross-testing and specimen-specific strategies. Alignment methods include all-vs-all, binary tree, iterative single-model refinement, multiple-model refinement, and self-symmetry alignment. An efficient angular search, Graphic Processing Unit (GPU) acceleration and both threaded and distributed parallelism are provided to speed up processing. Finally, automated simulations, per particle reconstruction of subtiltseries, and per-particle Contrast Transfer Function (CTF) correction have been implemented. Processing examples using both real and simulated data are shown for several structures. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. Assessing Model Characterization of Single Source ...

    Science.gov (United States)

    Aircraft measurements made downwind from specific coal fired power plants during the 2013 Southeast Nexus field campaign provide a unique opportunity to evaluate single source photochemical model predictions of both O3 and secondary PM2.5 species. The model did well at predicting downwind plume placement. The model shows similar patterns of an increasing fraction of PM2.5 sulfate ion to the sum of SO2 and PM2.5 sulfate ion by distance from the source compared with ambient based estimates. The model was less consistent in capturing downwind ambient based trends in conversion of NOX to NOY from these sources. Source sensitivity approaches capture near-source O3 titration by fresh NO emissions, in particular subgrid plume treatment. However, capturing this near-source chemical feature did not translate into better downwind peak estimates of single source O3 impacts. The model estimated O3 production from these sources but often was lower than ambient based source production. The downwind transect ambient measurements, in particular secondary PM2.5 and O3, have some level of contribution from other sources which makes direct comparison with model source contribution challenging. Model source attribution results suggest contribution to secondary pollutants from multiple sources even where primary pollutants indicate the presence of a single source. The National Exposure Research Laboratory (NERL) Computational Exposure Division (CED) develops and evaluates data, deci

  11. Research reactors

    International Nuclear Information System (INIS)

    Kowarski, L.

    1955-01-01

    It brings together the techniques data which are involved in the discussion about the utility for a research institute to acquire an atomic reactor for research purposes. This type of decision are often taken by non-specialist people who can need a brief presentation of a research reactor and its possibilities in term of research before asking advises to experts. In a first part, it draws up a list of the different research programs which can be studied by getting a research reactor. First of all is the reactor behaviour and kinetics studies (reproducibility factor, exploration of neutron density, effect of reactor structure, effect of material irradiation...). Physical studies includes study of the behaviour of the control system, studies of neutron resonance phenomena and study of the fission process for example. Chemical studies involves the study of manipulation and control of hot material, characterisation of nuclear species produced in the reactor and chemical effects of irradiation on chemical properties and reactions. Biology and medicine research involves studies of irradiation on man and animals, genetics research, food or medical tools sterilization and neutron beams effect on tumour for example. A large number of other subjects can be studied in a reactor research as reactor construction material research, fabrication of radioactive sources for radiographic techniques or applied research as in agriculture or electronic. The second part discussed the technological considerations when choosing the reactor type. The technological factors, which are considered for its choice, are the power of the reactor, the nature of the fuel which is used, the type of moderator (water, heavy water, graphite or BeO) and the reflector, the type of coolants, the protection shield and the control systems. In the third part, it described the characteristics (place of installation, type of combustible and comments) and performance (power, neutron flux ) of already existing

  12. Design and evaluation of a single-span bridge using ultra-high performance concrete.

    Science.gov (United States)

    2009-09-01

    "Research presented herein describes an application of a newly developed material called Ultra-High Performance Concrete (UHPC) to a : single-span bridge. The two primary objectives of this research were to develop a shear design procedure for possib...

  13. Researching Undergraduate Social Science Research

    Science.gov (United States)

    Rand, Jane

    2016-01-01

    The experience(s) of undergraduate research students in the social sciences is under-represented in the literature in comparison to the natural sciences or science, technology, engineering and maths (STEM). The strength of STEM undergraduate research learning environments is understood to be related to an apprenticeship-mode of learning supported…

  14. Action Research and Interactive Research

    DEFF Research Database (Denmark)

    First part of the book is written by senior researchers on specific issues like validity, gender, new forms of organisations, methodologies and methods, earlier and new trends. - The second part of the book is written by doctoral students reporting experiences doing action research in their PhD-projects....

  15. Single VDTA Based Dual Mode Single Input Multioutput Biquad Filter

    Directory of Open Access Journals (Sweden)

    Rajeshwari Pandey

    2016-01-01

    Full Text Available This paper presents a dual mode, single input multioutput (SIMO biquad filter configuration using single voltage differencing transconductance amplifier (VDTA, three capacitors, and a grounded resistor. The proposed topology can be used to synthesize low pass (LP, high pass (HP, and band pass (BP filter functions. It can be configured as voltage mode (VM or current mode (CM structure with appropriate input excitation choice. The angular frequency (ω0 of the proposed structure can be controlled independently of quality factor (Q0. Workability of the proposed biquad configuration is demonstrated through PSPICE simulations using 0.18 μm TSMC CMOS process parameters.

  16. Single particle tracking and single molecule energy transfer

    CERN Document Server

    Bräuchle, Christoph; Michaelis, Jens

    2009-01-01

    Closing a gap in the literature, this handbook gathers all the information on single particle tracking and single molecule energy transfer. It covers all aspects of this hot and modern topic, from detecting virus entry to membrane diffusion, and from protein folding using spFRET to coupled dye systems, as well recent achievements in the field. Throughout, the first-class editors and top international authors present content of the highest quality, making this a must-have for physical chemists, spectroscopists, molecular physicists and biochemists.

  17. Original Research

    African Journals Online (AJOL)

    home

    2014-06-02

    3372 (Online). Science, Technology and Arts Research Journal. Sci. ..... The reason behind these are geographical location, the nature of the forest. (whether it is moist or dry), altitudinal variation, age of the forest, degree of ...

  18. Aging research

    International Nuclear Information System (INIS)

    Ross, D.F. Jr.

    1988-01-01

    The USNRC Office of Nuclear Regulatory Research has developed a program for nuclear plant aging research (NPAR) to achieve an understanding of nuclear plant aging, its potential effects on safety, and methods for its detection and mitigation, sufficient for addressing safety and regulatory issues and supporting regulatory decisions on issues. Specifically, the NRC has aggressive research and regulatory programs associated with aging effects on piping, steam generators, containments, structures, and electrical and mechanical systems and components. In addition to safety assessment for the original license period for nuclear power plants, this aging information will be extremely useful in providing technical bases for efficient and effective regulation associated with possible license extension. This paper discusses the major activities of USNRC sponsored aging research program and recommends an approach to manage and handle aging at nuclear power plants

  19. Research Reports

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Centers for Medicare and Medicaid Services (CMS) research efforts span many topics, methods, and interests. Some projects address the Agencys immediate...

  20. Research Review

    OpenAIRE

    Anonymous

    1986-01-01

    Research Reviewed: "Crop Insurance for Agricultural Development: Issues and Experience"; "Linking Macroeconomic and Agricultural Policies for Adjustments with Growth: The Colombian Experience"; "Removal of Price Supports and Supply Controls for U.S. Tobacco: An Economic Analysis of the Impact"

  1. Research needs

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    Research needs were identified during working sessions for several potential separation options. These options include sequestering agents, solvent extraction, membranes, solid sorbents, novel approaches, organic separation and destruction methods, and radiation and chemical stability of separation materials

  2. Research Review

    OpenAIRE

    Anonymous

    1986-01-01

    Research Reviewed: "Sources of International Comparative Advantage: Theory and Evidence"; "Made in Washington: Food Policy and the Political Expedient"; "The Handbook of Econometrics"; "Farm Equipment Innovations in Eastern and Central Southern Africa"

  3. Research materials

    International Nuclear Information System (INIS)

    Anon.

    1977-01-01

    Development of techniques required for the preparation and characterization of ultrahigh-purity and controlled-impurity research specimens of interest to ORNL and other ERDA installations is described

  4. Disaster Research

    DEFF Research Database (Denmark)

    Given the tendency of books on disasters to predominantly focus on strong geophysical or descriptive perspectives and in-depth accounts of particular catastrophes, Disaster Research provides a much-needed multidisciplinary perspective of the area. This book is is structured thematically around key...... approaches to disaster research from a range of different, but often complementary academic disciplines. Each chapter presents distinct approaches to disaster research that is anchored in a particular discipline; ranging from the law of disasters and disaster historiography to disaster politics...... and anthropology of disaster. The methodological and theoretical contributions underlining a specific approach to disasters are discussed and illustrative empirical cases are examined that support and further inform the proposed approach to disaster research. The book thus provides unique insights into fourteen...

  5. Researching Experiences

    DEFF Research Database (Denmark)

    Gjedde, Lisa; Ingemann, Bruno

    , dialogue, moods, values and narratives have been investigated qualitatively with more than sixty informants in a range of projects. The processual methodological insights are put into a theoretical perspective and also presented as pragmatic dilemmas.      Researching Experiences is relevant not only...... for students and researchers in media and communication studies but also for practitioners within the fields of media, communication and experience design....... for researching experiences in a variety of settings ranging from the museum, to news photography, and interactive media. The research led to the development of a set of methodological tools and approaches we term the ReflexivityLab. The interaction in the experimental situation between the media and body...

  6. Air Research

    Science.gov (United States)

    EPA's air research provides the critical science to develop and implement outdoor air regulations under the Clean Air Act and puts new tools and information in the hands of air quality managers and regulators to protect the air we breathe.

  7. Executable research compendia in geoscience research infrastructures

    Science.gov (United States)

    Nüst, Daniel

    2017-04-01

    From generation through analysis and collaboration to communication, scientific research requires the right tools. Scientists create their own software using third party libraries and platforms. Cloud computing, Open Science, public data infrastructures, and Open Source enable scientists with unprecedented opportunites, nowadays often in a field "Computational X" (e.g. computational seismology) or X-informatics (e.g. geoinformatics) [0]. This increases complexity and generates more innovation, e.g. Environmental Research Infrastructures (environmental RIs [1]). Researchers in Computational X write their software relying on both source code (e.g. from https://github.com) and binary libraries (e.g. from package managers such as APT, https://wiki.debian.org/Apt, or CRAN, https://cran.r-project.org/). They download data from domain specific (cf. https://re3data.org) or generic (e.g. https://zenodo.org) data repositories, and deploy computations remotely (e.g. European Open Science Cloud). The results themselves are archived, given persistent identifiers, connected to other works (e.g. using https://orcid.org/), and listed in metadata catalogues. A single researcher, intentionally or not, interacts with all sub-systems of RIs: data acquisition, data access, data processing, data curation, and community support [3]. To preserve computational research [3] proposes the Executable Research Compendium (ERC), a container format closing the gap of dependency preservation by encapsulating the runtime environment. ERCs and RIs can be integrated for different uses: (i) Coherence: ERC services validate completeness, integrity and results (ii) Metadata: ERCs connect the different parts of a piece of research and faciliate discovery (iii) Exchange and Preservation: ERC as usable building blocks are the shared and archived entity (iv) Self-consistency: ERCs remove dependence on ephemeral sources (v) Execution: ERC services create and execute a packaged analysis but integrate with

  8. Latvian research

    International Nuclear Information System (INIS)

    1992-12-01

    The Latvian Council of Science asked the Danish Research Councils and the Danish Academy for Technical Sciences for help in evaluating Latvian scientific research. The background for this request was the Latvian desire to stimulate an approach towards full integration in the European society. Based on reports, site visits and interviews, 19 panels of experts covering all subject areas prepared evaluation reports. These detailed evaluations of actual research projects are included in the publication in addition to general recommendations. The panels recommend that Latvian authorities take into consideration when planning scientific research, especially with regard to those branches which contribute to the industrial development and social and economic sciences, that a balance should be made between long range basic, and short range applied, science activities. Despite the very serious economic conditions in Latvia, it was also advised that immediate measures should be taken to ensure a stable funding of the research system as the future development of Latvian society is dependent on the stability and high quality of its research activities. Other recommendations are given in detail. (AB)

  9. Coherent interaction of single molecules and plasmonic nanowires

    Science.gov (United States)

    Gerhardt, Ilja; Grotz, Bernhard; Siyushev, Petr; Wrachtrup, Jörg

    2017-09-01

    Quantum plasmonics opens the option to integrate complex quantum optical circuitry onto chip scale devices. In the past, often external light sources were used and nonclassical light was coupled in and out of plasmonic structures, such as hole arrays or waveguide structures. Another option to launch single plasmonic excitations is the coupling of single emitters in the direct proximity of, e.g., a silver or gold nanostructure. Here, we present our attempts to integrate the research of single emitters with wet-chemically grown silver nanowires. The emitters of choice are single organic dye molecules under cryogenic conditions, which are known to act as high-brightness and extremely narrow-band single photon sources. Another advantage is their high optical nonlinearity, such that they might mediate photon-photon interactions on the nanoscale. We report on the coupling of a single molecule fluorescence emission through the wire over the length of several wavelengths. The transmission of coherently emitted photons is proven by an extinction type experiment. As for influencing the spectral properties of a single emitter, we are able to show a remote change of the line-width of a single terrylene molecule, which is in close proximity to the nanowire.

  10. Czech Singles in the Market of Services

    Directory of Open Access Journals (Sweden)

    Martin Klepek

    2016-01-01

    Full Text Available The paper deals with specific characteristics of “Czech singles” with emphasis on services area. First, paper determinates the theoretical concept of services marketing in the first chapter. The major part of paper is devoted to primary marketing research. For purpose of collecting data, the method of questioning (combination of off‑line and on‑line approach was chosen. The questionnaire was given to 390 respondents living in the Czech Republic. The data were analysed by SPSS software. Results showed dissimilarities in leisure time activities based on different level of education and income as well as within the gender and age category and city, where particular single person live. Females spend more leisure time on cultural events, home activities as well as shopping and caring for appearance. They also engage with friends as a form of leisure time activity more than males. Educated singles travel more and attend more cultural events and at the same time, they educate themselves more often and do sports much regularly. We also found no relationship between income and shopping as a leisure time activity. This paper describes only a partial output of the primary marketing research with focus on the leisure time spending for the defined segment.

  11. Objectivist case study research

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Fachner, Jörg

    2016-01-01

    be achieved through the use of objectivist case study research. The strength of the case study design is that it allows for uncovering or suggesting causal relationships in real-life settings through an intensive and rich collection of data. According to Hilliard (1993), the opposite applies for extensive...... designs, in which a small amount of data is gathered on a large number of subjects. With the richness of data, the intensive design is ―the primary pragmatic reason for engaging in single-case or small N research‖ (p. 374) and for working from an idiographic rather than a nomothetic perspective....

  12. Understanding Traditional Research Impact Metrics.

    Science.gov (United States)

    Butler, Joseph S; Sebastian, Arjun S; Kaye, I David; Wagner, Scott C; Morrissey, Patrick B; Schroeder, Gregory D; Kepler, Christopher K; Vaccaro, Alexander R

    2017-05-01

    Traditionally, the success of a researcher has been judged by the number of publications he or she has published in peer-review, indexed, high impact journals. However, to quantify the impact of research in the wider scientific community, a number of traditional metrics have been used, including Impact Factor, SCImago Journal Rank, Eigenfactor Score, and Article Influence Score. This article attempts to provide a broad overview of the main traditional impact metrics that have been used to assess scholarly output and research impact. We determine that there is no perfect all-encompassing metric to measure research impact, and, in the modern era, no single traditional metric is capable of accommodating all facets of research impact. Academics and researchers should be aware of the advantages and limitations of traditional metrics and should be judicious when selecting any metrics for an objective assessment of scholarly output and research impact.

  13. Allographic agraphia for single letters.

    Science.gov (United States)

    Menichelli, Alina; Machetta, Francesca; Zadini, Antonella; Semenza, Carlo

    2012-01-01

    The case is reported of a patient (PS) who, following acute encephalitis with residual occipito-temporal damage, showed a selective deficit in writing cursive letters in isolation, but no difficulty to write cursive-case words and non-words. Notably, he was able to recognize the same allographs he could not write and to produce both single letters and words in print. In addition to this selective single letter writing difficulty, the patient demonstrated an inability to correctly perform a series of imagery tasks for cursive letters. PS's performance may indicate that single letter production requires explicit imagery. Explicit imagery may not be required, instead, when letters have to be produced in the context of a word: letter production in this case may rely on implicit retrieval of well learned scripts in a procedural way.

  14. From joint to single audits

    DEFF Research Database (Denmark)

    Holm, Claus; Thinggaard, Frank

    2018-01-01

    This study analyses audit quality differences between audits by a single big audit firm and joint audits with either one or two big audit firms. We exploit the unique situation in Denmark beginning on 1 January 2005, at which time a long-standing mandatory joint audit system for listed companies...... was replaced by a voluntary joint audit system. First, we report the results of a survey of Danish CFOs’ views on and their experiences with the choice of single or joint audits and their perceptions of audit quality. Second, based on data from the mandatory joint audit abolition year and the following two...... years, we test the audit quality differences using abnormal accruals. Most CFOs perceive that audit quality by a single big four audit firm is the same as it is in joint audits with either one or two big four audit firms. The results of our empirical analysis are in line with the perceptions. We find...

  15. Health Insurance without Single Crossing

    DEFF Research Database (Denmark)

    Boone, Jan; Schottmüller, Christoph

    2017-01-01

    Standard insurance models predict that people with high risks have high insurance coverage. It is empirically documented that people with high income have lower health risks and are better insured. We show that income differences between risk types lead to a violation of single crossing...... in an insurance model where people choose treatment intensity. We analyse different market structures and show the following: If insurers have market power, the violation of single crossing caused by income differences and endogenous treatment choice can explain the empirically observed outcome. Our results do...

  16. Single transverse mode protein laser

    Science.gov (United States)

    Dogru, Itir Bakis; Min, Kyungtaek; Umar, Muhammad; Bahmani Jalali, Houman; Begar, Efe; Conkar, Deniz; Firat Karalar, Elif Nur; Kim, Sunghwan; Nizamoglu, Sedat

    2017-12-01

    Here, we report a single transverse mode distributed feedback (DFB) protein laser. The gain medium that is composed of enhanced green fluorescent protein in a silk fibroin matrix yields a waveguiding gain layer on a DFB resonator. The thin TiO2 layer on the quartz grating improves optical feedback due to the increased effective refractive index. The protein laser shows a single transverse mode lasing at the wavelength of 520 nm with the threshold level of 92.1 μJ/ mm2.

  17. Single liner shipping service design

    DEFF Research Database (Denmark)

    Plum, Christian Edinger Munk; Pisinger, David; Salazar-González, Juan-José

    2014-01-01

    The design of container shipping networks is an important logistics problem, involving assets and operational costs measured in billions of dollars. To guide the optimal deployment of the ships, a single vessel round trip is considered by minimizing operational costs and flowing the best paying...... demand under commercially driven constraints. This paper introduces the Single Liner Shipping Service Design Problem. Arc-flow and path-flow models are presented using state-of-the-art elements from the wide literature on pickup and delivery problems. A Branch-and-Cut-and-Price algorithm is proposed...

  18. Genomic Sequencing of Single Microbial Cells from Environmental Samples

    Energy Technology Data Exchange (ETDEWEB)

    Ishoey, Thomas; Woyke, Tanja; Stepanauskas, Ramunas; Novotny, Mark; Lasken, Roger S.

    2008-02-01

    Recently developed techniques allow genomic DNA sequencing from single microbial cells [Lasken RS: Single-cell genomic sequencing using multiple displacement amplification, Curr Opin Microbiol 2007, 10:510-516]. Here, we focus on research strategies for putting these methods into practice in the laboratory setting. An immediate consequence of single-cell sequencing is that it provides an alternative to culturing organisms as a prerequisite for genomic sequencing. The microgram amounts of DNA required as template are amplified from a single bacterium by a method called multiple displacement amplification (MDA) avoiding the need to grow cells. The ability to sequence DNA from individual cells will likely have an immense impact on microbiology considering the vast numbers of novel organisms, which have been inaccessible unless culture-independent methods could be used. However, special approaches have been necessary to work with amplified DNA. MDA may not recover the entire genome from the single copy present in most bacteria. Also, some sequence rearrangements can occur during the DNA amplification reaction. Over the past two years many research groups have begun to use MDA, and some practical approaches to single-cell sequencing have been developed. We review the consensus that is emerging on optimum methods, reliability of amplified template, and the proper interpretation of 'composite' genomes which result from the necessity of combining data from several single-cell MDA reactions in order to complete the assembly. Preferred laboratory methods are considered on the basis of experience at several large sequencing centers where >70% of genomes are now often recovered from single cells. Methods are reviewed for preparation of bacterial fractions from environmental samples, single-cell isolation, DNA amplification by MDA, and DNA sequencing.

  19. Recent Trends on Micro/Nanofluidic Single Cell Electroporation

    Directory of Open Access Journals (Sweden)

    Tuhin Subhra Santra

    2013-09-01

    Full Text Available The behaviors of cell to cell or cell to environment with their organelles and their intracellular physical or biochemical effects are still not fully understood. Analyzing millions of cells together cannot provide detailed information, such as cell proliferation, differentiation or different responses to external stimuli and intracellular reaction. Thus, single cell level research is becoming a pioneering research area that unveils the interaction details in high temporal and spatial resolution among cells. To analyze the cellular function, single cell electroporation can be conducted by employing a miniaturized device, whose dimension should be similar to that of a single cell. Micro/nanofluidic devices can fulfill this requirement for single cell electroporation. This device is not only useful for cell lysis, cell to cell fusion or separation, insertion of drug, DNA and antibodies inside single cell, but also it can control biochemical, electrical and mechanical parameters using electroporation technique. This device provides better performance such as high transfection efficiency, high cell viability, lower Joule heating effect, less sample contamination, lower toxicity during electroporation experiment when compared to bulk electroporation process. In addition, single organelles within a cell can be analyzed selectively by reducing the electrode size and gap at nanoscale level. This advanced technique can deliver (in/out biomolecules precisely through a small membrane area (micro to nanoscale area of the single cell, known as localized single cell membrane electroporation (LSCMEP. These articles emphasize the recent progress in micro/nanofluidic single cell electroporation, which is potentially beneficial for high-efficient therapeutic and delivery applications or understanding cell to cell interaction.

  20. International Journal of Health Research

    African Journals Online (AJOL)

    Erah

    2008-06-12

    Jun 12, 2008 ... manuscripts should normally be 10,000 words (20 single-spaced typewritten pages) for review, 6,000 words for research articles, 3,000 for technical ... All manuscripts must be in MS Word and in English and should be submitted online at .... inoculation of 106 cells/per mouse. Animals. Male adult Swiss ...

  1. Operational Research: A multidisciplinary discipline

    DEFF Research Database (Denmark)

    Vidal, Rene Victor Valqui

    2005-01-01

    This paper is focusing on the following question: What is Operational Research (OR)? We will show that there is not a single and simple answer. Epistemological assumptions and practical traditions define different types of OR. We have identified three: The technical or hard OR, the practical or s...

  2. Researching experiences

    DEFF Research Database (Denmark)

    Gjedde, Lisa; Ingemann, Bruno

    In the beginning was - not the word - but the experience. This phenomenological approach provides the basis for this book, which focuses on how a person-in-situation experiences and constructs meaning from a variety of cultural visual events. This book presents video-based processual methods...... for researching experiences in a variety of settings ranging from the museum, to news photography, and interactive media. The research led to the development of a set of methodological tools and approaches we term the reflexivity lab. The interaction in the experimental situation between the media and body......, dialogue, moods, values and narratives have been investigated qualitatively with more than sixty informants in a range of projects. The processual methodological insights are put into a theoretical perspective and also presented as pragmatic dilemmas. Researching Experiences is relevant not only...

  3. Quantitative research.

    Science.gov (United States)

    Watson, Roger

    2015-04-01

    This article describes the basic tenets of quantitative research. The concepts of dependent and independent variables are addressed and the concept of measurement and its associated issues, such as error, reliability and validity, are explored. Experiments and surveys – the principal research designs in quantitative research – are described and key features explained. The importance of the double-blind randomised controlled trial is emphasised, alongside the importance of longitudinal surveys, as opposed to cross-sectional surveys. Essential features of data storage are covered, with an emphasis on safe, anonymous storage. Finally, the article explores the analysis of quantitative data, considering what may be analysed and the main uses of statistics in analysis.

  4. Catalogue of research projects

    International Nuclear Information System (INIS)

    Skarp, K.

    1993-01-01

    The Centre for Materials Science serves as an umbrella for organizations involved in materials research at the two Universities and at certain branch institutes in the Gothenburg region. The general goal of the Centre is to promote materials research among the member organizations and to provide a link to industry and to the society at large. Members of the Centre work on most aspects of modern materials research, ranging from single-atom manipulation and theoretical simulations to biomaterials and production engineering. In order to give a presentation of the members and their research, the Centre produces an inventory of materials research projects approximately every four years. The 1993 issue is somewhat more extensive than previous editions, detailing e.g. also scientific equipment and listing work published during the past four years. The register covers the following main headings: General materials and surface science; Materials chemistry; Polymers and fibres; Biomaterials; Clusters and fine particles; Electronic and opto-electronic materials; Superconductors and nanometer structures; Ceramics; Metals; Building materials; Production and materials processing

  5. Management research

    International Nuclear Information System (INIS)

    Berry, M.

    1988-01-01

    The 1988 progress report of the Management Research center (Polytechnic School, France), is presented. The Center research programs include the management of different organizations, such as industry, administrative systems, hospitals and cultural systems. The investigations performed concern the improvement and better knowledge of the new methods of analysis: the role of the speech, the logic conflicts; the crisis development, symptoms and effects; the relationship between the management practices and the prevailing ideas or theories. The approach adopted by the scientists involves the accurate analysis of the essential management activities. The investigations carried out in 1988 are summarized. The published papers, the congress communications and the thesis are listed [fr

  6. Research Results

    Science.gov (United States)

    2011-12-01

    Research on Global Carbon Emission and Sequestration NSFC Funded Project Made Significant Progress in Quantum Dynamics Functional Human Blood Protein Obtained from Rice How Giant Pandas Thrive on a Bamboo Diet New Evidence of Interpersonal Violence from 129,000 Years Ago Found in China Aptamer-Mediated Efficient Capture and Release of T Lymphocytes on Nanostructured Surfaces BGI Study Results on Resequencing 50 Accessions of Rice Cast New Light on Molecular Breeding BGI Reports Study Results on Frequent Mutation of Genes Encoding UMPP Components in Kidney Cancer Research on Habitat Shift Promoting Species Diversification

  7. Prospects of Single Tax Payers

    Directory of Open Access Journals (Sweden)

    Tofan Ivan M.

    2014-03-01

    Full Text Available The article speaks about problem aspects of taxation, which were set by the state for the single tax administering due to permanent and system changes in the tax legislation. It shows the necessity of search for alternative methods of administering in the process of taxation of single tax payers by fiscal services. The goal of the article is the study of prospects of further taxation of entrepreneurs – single tax payers on the basis of analysis of conditions and principles created by the state for the business. The article used methods of system analysis, comparison, forecasting and modelling. It analyses the process of evolution of the simplified taxation system, accounting and reporting from the moment of its adoption until today. The article presents the structure of the quantitative composition of single tax payers depending on the selected groups. It marks out and characterises administrative and fiscal factors that do not facilitate further development of entrepreneurship in Ukraine. In the result of the conducted studies the article outlines problem aspects of organisation of taxation of the small business and offers specific and real ways of their overcoming or partial solution.

  8. Single port Billroth I gastrectomy

    Directory of Open Access Journals (Sweden)

    Jeremy R Huddy

    2013-01-01

    Full Text Available Introduction: Experience has allowed increasingly complex procedures to be undertaken by single port surgery. We describe a technique for single port Billroth I gastrectomy with a hand-sewn intracorporeal anastomosis in the resection of a benign tumour diagnosed incidentally on a background of cholelithiasis. Materials and Methods: Single port Billroth I gastrectomy and cholecystectomy was performed using a transumbilical quadport. Flexible tipped camera and straight conventional instruments were used throughout the procedure. The stomach was mobilised including a limited lymph node dissection and resection margins in the proximal antrum and duodenum were divided with a flexible tipped laparoscopic stapler. The lesser curve was reconstructed and an intracorporal hand sewn two layer end-to-end anastomosis was performed using unidirectional barbed sutures. Intraoperative endoscopy confirmed the anastomosis to be patent without leak. Results: Enteral feed was started on the day of surgery, increasing to a full diet by day 6. Analgesic requirements were a patient-controlled analgesia morphine pump for 4 postoperative days and paracetamol for 6 days. There were no postoperative complications and the patient was discharged on the eighth day. Histology confirmed gastric submucosal lipoma. Discussion: As technology improves more complex procedures are possible by single port laparoscopic surgery. In this case, flexible tipped cameras and unidirectional barbed sutures have facilitated an intracorporal hand-sewn two layer end-to-end anastomosis. Experience will allow such techniques to become mainstream.

  9. Single chirality through crystal grinding

    NARCIS (Netherlands)

    Noorduin, W.L.

    2010-01-01

    The properties of chiral molecules in living organisms can be different for left- and right-handed molecules. Therefore, ways to produce molecules of single handedness are of paramount importance, especially for economical, high yielding processes to synthesize pharmaceutical compounds that must be

  10. Single-mode optical fibres

    CERN Document Server

    Cancellieri, G

    1991-01-01

    This book describes signal propagation in single-mode optical fibres for telecommunication applications. Such description is based on the analysis of field propagation, considering waveguide properties and also some of the particular characteristics of the material fibre. The book covers such recent advances as, coherent transmissions; optical amplification; MIR fibres; polarization maintaining; polarization diversity and photon counting.

  11. Single cell electroporation on chip

    NARCIS (Netherlands)

    Valero, Ana

    2006-01-01

    In this thesis the results of the development of microfluidic cell trap devices for single cell electroporation are described, which are to be used for gene transfection. The performance of two types of Lab-on-a-Chip trapping devices was tested using beads and cells, whereas the functionality for

  12. CERN single sign on solution

    International Nuclear Information System (INIS)

    Ormancey, E

    2008-01-01

    The need for Single Sign On has always been restricted by the absence of cross platform solutions: a single sign on working only on one platform or technology is nearly useless. The recent improvements in Web Services Federation (WS-Federation) standard enabling federation of identity, attribute, authentication and authorization information can now provide real extended Single Sign On solutions. Various solutions have been investigated at CERN and now, a Web SSO solution using some parts of WS-Federation technology is available. Using the Shibboleth Service Provider module for Apache hosted web sites and Microsoft ADFS as the identity provider linked to Active Directory user, users can now authenticate on any web application using a single authentication platform, providing identity, user information (building, phone...) as well as group membership enabling authorization possibilities. A typical scenario: a CERN user can now authenticate on a Linux/Apache website using Windows Integrated credentials, and his Active Directory group membership can be checked before allowing access to a specific web page

  13. Single photon searches at PEP

    Energy Technology Data Exchange (ETDEWEB)

    Hollebeek, R.

    1985-12-01

    The MAC and ASP searches for events with a single photon and no other observed particles are reviewed. New results on the number of neutrino generations and limits on selection, photino, squark and gluino masses from the ASP experiment are presented.

  14. Single photon searches at PEP

    International Nuclear Information System (INIS)

    Hollebeek, R.

    1985-12-01

    The MAC and ASP searches for events with a single photon and no other observed particles are reviewed. New results on the number of neutrino generations and limits on selection, photino, squark and gluino masses from the ASP experiment are presented

  15. A Single-Pulse Integrator

    DEFF Research Database (Denmark)

    Miller, Arne

    1974-01-01

    A single-pulse integrator is described. It gives a relative measure of the integral of the output signal from a coil monitor on the Risø 10 MeV linear accelerator, and displays the value on a digital voltmeter. The reproduccibility is found to be better than ±1% for an accelerated pulse charge...

  16. Acceleration of single pixel imaging

    Science.gov (United States)

    Nitta, K.

    2018-01-01

    A method for single pixel imaging (SPI) is introduced. The method is proposed to accelerate optical measurement. The method is also useful for high-definition imaging. The processing procedure of the method is described and some features of the based on the proposed method is described.

  17. A new research trend in social neuroscience

    DEFF Research Database (Denmark)

    Liu, Tao; Pelowski, Matthew John

    2014-01-01

    The ability to flexibly modulate our behaviors in social contexts and to successfully interact with other persons is a fundamental, but pivotal, requirement for human survival. Although previous social neuroscience research with single individuals has contributed greatly to our understanding...

  18. Original Research

    African Journals Online (AJOL)

    home

    2014-12-23

    3372 (Online). Science, Technology and Arts Research Journal. Sci. Technol. Arts Res. J., Oct-Dec 2014, 3(4): 71-78 ..... However, the reason behind the taste chemistry for the pork in the present study was not clear except.

  19. Original Research

    African Journals Online (AJOL)

    home

    2014-12-22

    3372 (Online). Science, Technology and Arts Research Journal. Sci. Technol. Arts Res. J., Oct-Dec 2014, 3(4): 122-134 ...... species of these two families. The reason behind the fact that samma (Urtica simensis) was cited by most.

  20. Original Research

    African Journals Online (AJOL)

    2013-12-17

    .starjournal.org ... Soil pH can vary from 7 to 8.3 when only. Original Research. DOI: http://dx.doi.org/10.4314/star.v2i4.9 ...... to solve fertility management related problems in the area. Thus identification of the reasons behind.

  1. Research Article

    African Journals Online (AJOL)

    2016-06-05

    Jun 5, 2016 ... Palladium (Pd) accumulates in many organs and renders many deleterious effects. Although the Pd toxicity has been documented, the precise mechanism of Pd toxicity still needs to be elucidated. In the current research, a hepatotoxicity mechanism of Pd has been investigated. Our findings clearly indicate ...

  2. Research Paper:

    African Journals Online (AJOL)

    Shanu

    2014-01-08

    Jan 8, 2014 ... Forty years in capsaicin research for sensory pharmacology and physiology. Neuropeptides 38:377-384. Thomas E (2002). Tissue culture studies in Arachis hypogea L. and. Vignaunguiculata (L.) Walp. for micropropagation and cell line selection for amino acid overproduction, Ph.D. Thesis, University of.

  3. Research Article

    African Journals Online (AJOL)

    2018-01-01

    Jan 1, 2018 ... ferrocene derivatives and potentially all analogous organometallic compounds. The results confirm the utility of use of square wave voltammetry techniques for measuring octanol-water partition coefficients of ferrocene derivatives. 5. ACKNOWLEDGEMENT. This research was financed by the laboratory of ...

  4. Research Blog

    NARCIS (Netherlands)

    Jautze, K.J.

    2014-01-01

    Welcome to my personal research blog. I'm a PhD candidate from the Netherlands who has an interest in language and literature. In the project The Riddle of Literary Quality my colleagues and I explore the assumption that formal characteristics play a role in the aesthetic appreciation of novels. In

  5. Research Article

    African Journals Online (AJOL)

    2016-06-11

    Jun 11, 2016 ... This research aimed to study the effects of window position on natural cross ventilation in Vernacular architecture of .... sustainable development and keep construction in accordance with the principles of climate. 2 Qanbari and. Sharif. Qajeh. Pasha, 2013. The use of vernacular architecture in the design of.

  6. Research Article

    African Journals Online (AJOL)

    2016-06-25

    Jun 25, 2016 ... This article aims at evaluating the fun oftware which are employed for approximate solution in optimization been produced least squares by usual methods for linear and non enetic algorithm in this research. t Squares, Genetic Algorithm, Linear Model, Nonlinear Model, S dence, e-mail: c.author@mail.com.

  7. original research

    African Journals Online (AJOL)

    jenny

    Original Research: Computer-based learning for the enhancement of breastfeeding training. 2009;22(3) ... Conclusion: It is recommended that validated computer-based breastfeeding training modules be integrated as part of multi-media methods .... training and consultations at community and individual level. 3. 0.

  8. Research Article

    African Journals Online (AJOL)

    2016-01-01

    Jan 1, 2016 ... ABSTRACT. One of the hottest issues in the recent environmental research worldwide has become the harmful effects of climate change on the ecosystems and environment due to global warming. Bangladesh is one of the most vulnerable countries not only in the South East Asia but also in the world.

  9. Research Article

    African Journals Online (AJOL)

    1 janv. 2017 ... Agronomy Departement, Fac. Lif. 2. Ecology and Biology Department, Fac. 3. National Center for Seed and Plants Contr. Received: 05 September 2016 / Accepted: 1. ABSTRACT. This research was conducted to screen populations of bread wheat (Triticum aesti. The results indicated the presence of suffic.

  10. Research Summaries

    Science.gov (United States)

    Brock, Stephen E., Ed.

    2010-01-01

    This column features summaries of research articles from 3 recent crisis management publications. The first, "School Shootings and Counselor Leadership: Four Lessons from the Field" summarized by Kristi Fenning, was conducted as the result of the increased demand for trained crisis personnel on school campuses. Survey participants were…

  11. Research Article

    African Journals Online (AJOL)

    2016-06-18

    Jun 18, 2016 ... different modes of equations is used in a number of semi-empirical equations. Due to the high pressure, semi-empirical equations can not predict the solubility of solids as well. The cubic equations of state have been used by many researchers because of their simplicity, but these equations face problems ...

  12. Population Research.

    Science.gov (United States)

    National Inst. of Child Health and Human Development (NIH), Bethesda, MD.

    The scope of population research as carried on by the National Institute of Child Health and Human Development (NICHD) is set forth in this booklet. Population problems of the world, United States, and the individual are considered along with international population policies based on voluntary family planning programs. NICHD goals for biological…

  13. Energy research

    International Nuclear Information System (INIS)

    1979-03-01

    Status reports are given for the Danish Trade Ministry's energy research projects on uranium prospecting and extraction, oil and gas recovery, underground storage of district heating, electrochemical energy storage systems, wind mills, coal deposits, coal cambustion, energy consumption in buildings, solar heat, biogas, compost heat. (B.P.)

  14. RESEARCH ARTICLE

    Indian Academy of Sciences (India)

    Navya

    2012; Thomas et al. 2016). As IGF1 plays crucial role in almost all body functions, including, growth, reproduction and metabolism, the current research was designed to investigate the nucleotide sequences ..... Rep. 39, 9801–9807. Koohmaraie M., Shackelford S. D., Wheeler T. L., Lonergan S. M. and Doumit M. E. 1995 A.

  15. Research Article

    African Journals Online (AJOL)

    2016-06-18

    Jun 18, 2016 ... ABSTRACT. Users encounter a huge volume of papers i. IEEE Explore, ACM Digital library, Goo make some difficulties for researcher. Recommender systems contain successful their priorities. These systems present a p special kind of relevant data or thei. Recommendersystem based on personaliza.

  16. Research medicine

    International Nuclear Information System (INIS)

    Anon.

    1979-01-01

    Highlights of the research effort during 1978 and 1979 include the development and use of a 280-crystal position tomograph; use of 11 C-labeled methionine in studies of heart metabolism and brain metabolism in humans; and studies of the megakaryocytic cell system

  17. Research Article

    African Journals Online (AJOL)

    2016-06-18

    Jun 18, 2016 ... Research Article. Journal of Fundamental and Applied Sciences is licensed under a Creative Commons Attribution-NonCommercial 4.0. International ... and breakthrough for human not only in some location and for some year rather for the ... they are used for the new source for building a new structure.

  18. Original Research

    African Journals Online (AJOL)

    home

    2014-12-21

    Dec 21, 2014 ... ISSN: 2226-7522(Print) and 2305-3372 (Online). Science, Technology and Arts Research Journal. Sci. Technol. Arts Res. J., Oct-Dec 2014, 3(4): 01-09. Journal Homepage: http://www.starjournal.org/. Correlation and Divergence Analysis for Phenotypic Traits in Sesame. (Sesamum indicum L.) Genotypes.

  19. Rainfall Research.

    Science.gov (United States)

    Melber, Leah M.

    2003-01-01

    Presents procedures for weather studies as exciting and relatively simple research projects for students to perform. Expects that students gain an accurate view of the scientific process in addition to real-world experience as they face challenging setbacks and make unexpected discoveries along the way. Includes cross-curricular applications.…

  20. Quantitative research

    DEFF Research Database (Denmark)

    Wigram, Anthony Lewis

    2003-01-01

    possible and desirable. It is not just a type of research done in a laboratory, or by PhD students. Some for of reliable measurement can be applied to many clinical situationsto evaluate the effects of therapy over time, or the difference between clients who receive therapy and those who don't. Evaluating...