WorldWideScience

Sample records for simulated patient methods

  1. Assessing Critical Thinking Outcomes of Dental Hygiene Students Utilizing Virtual Patient Simulation: A Mixed Methods Study.

    Science.gov (United States)

    Allaire, Joanna L

    2015-09-01

    Dental hygiene educators must determine which educational practices best promote critical thinking, a quality necessary to translate knowledge into sound clinical decision making. The aim of this small pilot study was to determine whether virtual patient simulation had an effect on the critical thinking of dental hygiene students. A pretest-posttest design using the Health Science Reasoning Test was used to evaluate the critical thinking skills of senior dental hygiene students at The University of Texas School of Dentistry at Houston Dental Hygiene Program before and after their experience with computer-based patient simulation cases. Additional survey questions sought to identify the students' perceptions of whether the experience had helped develop their critical thinking skills and improved their ability to provide competent patient care. A convenience sample of 31 senior dental hygiene students completed both the pretest and posttest (81.5% of total students in that class); 30 senior dental hygiene students completed the survey on perceptions of the simulation (78.9% response rate). Although the results did not show a significant increase in mean scores, the students reported feeling that the use of virtual patients was an effective teaching method to promote critical thinking, problem-solving, and confidence in the clinical realm. The results of this pilot study may have implications to support the use of virtual patient simulations in dental hygiene education. Future research could include a larger controlled study to validate findings from this study.

  2. The role of simulation in mixed-methods research: a framework & application to patient safety.

    Science.gov (United States)

    Guise, Jeanne-Marie; Hansen, Matthew; Lambert, William; O'Brien, Kerth

    2017-05-04

    Research in patient safety is an important area of health services research and is a national priority. It is challenging to investigate rare occurrences, explore potential causes, and account for the complex, dynamic context of healthcare - yet all are required in patient safety research. Simulation technologies have become widely accepted as education and clinical tools, but have yet to become a standard tool for research. We developed a framework for research that integrates accepted patient safety models with mixed-methods research approaches and describe the performance of the framework in a working example of a large National Institutes of Health (NIH)-funded R01 investigation. This worked example of a framework in action, identifies the strengths and limitations of qualitative and quantitative research approaches commonly used in health services research. Each approach builds essential layers of knowledge. We describe how the use of simulation ties these layers of knowledge together and adds new and unique dimensions of knowledge. A mixed-methods research approach that includes simulation provides a broad multi-dimensional approach to health services and patient safety research.

  3. Beyond finite elements: a comprehensive, patient-specific neurosurgical simulation utilizing a meshless method.

    Science.gov (United States)

    Miller, K; Horton, A; Joldes, G R; Wittek, A

    2012-10-11

    To be useful in clinical (surgical) simulations, a method must use fully nonlinear (both geometric and material) formulations to deal with large (finite) deformations of tissues. The method must produce meaningful results in a short time on consumer hardware and not require significant manual work while discretizing the problem domain. In this paper, we showcase the Meshless Total Lagrangian Explicit Dynamics Method (MTLED) which meets these requirements, and use it for computing brain deformations during surgery. The problem geometry is based on patient-specific MRI data and includes the parenchyma, tumor, ventricles and skull. Nodes are distributed automatically through the domain rendering the normally difficult problem of creating a patient-specific computational grid a trivial exercise. Integration is performed over a simple, regular background grid which does not need to conform to the geometry boundaries. Appropriate nonlinear material formulation is used. Loading is performed by displacing the parenchyma surface nodes near the craniotomy and a finite frictionless sliding contact is enforced between the skull (rigid) and parenchyma. The meshless simulation results are compared to both intraoperative MRIs and Finite Element Analysis results for multiple 2D sections. We also calculate Hausdorff distances between the computed deformed surfaces of the ventricles and those observed intraoperatively. The difference between previously validated Finite Element results and the meshless results presented here is less than 0.2mm. The results are within the limits of neurosurgical and imaging equipment accuracy (~1 mm) and demonstrate the method's ability to fulfill all of the important requirements for surgical simulation. Copyright © 2012 Elsevier Ltd. All rights reserved.

  4. Manufacture of patient-specific vascular replicas for endovascular simulation using fast, low-cost method

    Science.gov (United States)

    Kaneko, Naoki; Mashiko, Toshihiro; Ohnishi, Taihei; Ohta, Makoto; Namba, Katsunari; Watanabe, Eiju; Kawai, Kensuke

    2016-12-01

    Patient-specific vascular replicas are essential to the simulation of endovascular treatment or for vascular research. The inside of silicone replica is required to be smooth for manipulating interventional devices without resistance. In this report, we demonstrate the fabrication of patient-specific silicone vessels with a low-cost desktop 3D printer. We show that the surface of an acrylonitrile butadiene styrene (ABS) model printed by the 3D printer can be smoothed by a single dipping in ABS solvent in a time-dependent manner, where a short dip has less effect on the shape of the model. The vascular mold is coated with transparent silicone and then the ABS mold is dissolved after the silicone is cured. Interventional devices can pass through the inside of the smoothed silicone vessel with lower pushing force compared to the vessel without smoothing. The material cost and time required to fabricate the silicone vessel is about USD $2 and 24 h, which is much lower than the current fabrication methods. This fast and low-cost method offers the possibility of testing strategies before attempting particularly difficult cases, while improving the training of endovascular therapy, enabling the trialing of new devices, and broadening the scope of vascular research.

  5. Patient flow within UK emergency departments: a systematic review of the use of computer simulation modelling methods

    Science.gov (United States)

    Mohiuddin, Syed; Busby, John; Savović, Jelena; Richards, Alison; Northstone, Kate; Hollingworth, William; Donovan, Jenny L; Vasilakis, Christos

    2017-05-09

    Overcrowding in the emergency department (ED) is common in the UK as in other countries worldwide. Computer simulation is one approach used for understanding the causes of ED overcrowding and assessing the likely impact of changes to the delivery of emergency care. However, little is known about the usefulness of computer simulation for analysis of ED patient flow. We undertook a systematic review to investigate the different computer simulation methods and their contribution for analysis of patient flow within EDs in the UK. We searched eight bibliographic databases (MEDLINE, EMBASE, COCHRANE, WEB OF SCIENCE, CINAHL, INSPEC, MATHSCINET and ACM DIGITAL LIBRARY) from date of inception until 31 March 2016. Studies were included if they used a computer simulation method to capture patient progression within the ED of an established UK National Health Service hospital. Studies were summarised in terms of simulation method, key assumptions, input and output data, conclusions drawn and implementation of results. Twenty-one studies met the inclusion criteria. Of these, 19 used discrete event simulation and 2 used system dynamics models. The purpose of many of these studies (n=16; 76%) centred on service redesign. Seven studies (33%) provided no details about the ED being investigated. Most studies (n=18; 86%) used specific hospital models of ED patient flow. Overall, the reporting of underlying modelling assumptions was poor. Nineteen studies (90%) considered patient waiting or throughput times as the key outcome measure. Twelve studies (57%) reported some involvement of stakeholders in the simulation study. However, only three studies (14%) reported on the implementation of changes supported by the simulation. We found that computer simulation can provide a means to pretest changes to ED care delivery before implementation in a safe and efficient manner. However, the evidence base is small and poorly developed. There are some methodological, data, stakeholder

  6. USU Patient Simulation Center

    Data.gov (United States)

    Federal Laboratory Consortium — he National Capital Area (NCA) Medical Simulation Center is a state-of-the-art training facility located near the main USU campus. It uses simulated patients (i.e.,...

  7. Evaluating medical student engagement during virtual patient simulations: a sequential, mixed methods study.

    Science.gov (United States)

    McCoy, Lise; Pettit, Robin K; Lewis, Joy H; Allgood, J Aaron; Bay, Curt; Schwartz, Frederic N

    2016-01-16

    Student engagement is an important domain for medical education, however, it is difficult to quantify. The goal of this study was to investigate the utility of virtual patient simulations (VPS) for increasing medical student engagement. Our aims were specifically to investigate how and to what extent the VPS foster student engagement. This study took place at A.T. Still University School of Osteopathic Medicine in Arizona (ATSU-SOMA), in the USA. First year medical students (n = 108) worked in teams to complete a series of four in-class virtual patient case studies. Student engagement was measured, defined as flow, interest, and relevance. These dimensions were measured using four data collection instruments: researcher observations, classroom photographs, tutor feedback, and an electronic exit survey. Qualitative data were analyzed using a grounded theory approach. Triangulation of findings between the four data sources indicate that VPS foster engagement in three facets: 1) Flow. In general, students enjoyed the activities, and were absorbed in the task at hand. 2) Interest. Students demonstrated interest in the activities, as evidenced by enjoyment, active discussion, and humor. Students remarked upon elements that caused cognitive dissonance: excessive text and classroom noise generated by multi-media and peer conversations. 3) Relevance. VPS were relevant, in terms of situational clinical practice, exam preparation, and obtaining concrete feedback on clinical decisions. Researchers successfully introduced a new learning platform into the medical school curriculum. The data collected during this study were also used to improve new learning modules and techniques associated with implementing them in the classroom. Results of this study assert that virtual patient simulations foster engagement in terms of flow, relevance, and interest.

  8. Contribution of a reflective debriefing to nursing students' clinical judgment in patient deterioration simulations: A mixed-methods study.

    Science.gov (United States)

    Lavoie, Patrick; Pepin, Jacinthe; Cossette, Sylvie

    2017-03-01

    While reflection is a hallmark of debriefing, there is little understanding of how it contributes to nursing students' clinical judgment. The aim of this study was to describe how nursing students perceived that the Reflective dEbriefing after a PatieNt Deterioration simulation (REsPoND) fostered learning and how it contributed to their clinical judgment in patient deterioration simulations. A sequential explanatory mixed-methods study. Nineteen students who showed the greatest clinical judgment score variation in a randomized controlled trial of the effectiveness of REsPoND. Students participated in interviews on their learning experience in REsPoND. Data were subjected to thematic analysis and themes were contrasted according to students' score variations. Through guided exchanges with their peers, students configured a causes-observations-interventions framework that embodied their understanding of the patient's situation. They evaluated their own simulation performance based on that framework. The contribution of REsPoND to students' clinical judgment differed depending on (1) the value placed on the review of the simulation through a systematic assessment approach; (2) their focus on anticipating the situation or on performing in the simulation; and (3) their preference for who participated more in debriefing. Clinical judgment might be improved when a systematic assessment approach is used to structure debriefing. The relationship between reflection and self-assessment during debriefing remains to be disentangled. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Perfusion vector - a new method to quantify myocardial perfusion scintigraphy images: a simulation study with validation in patients

    DEFF Research Database (Denmark)

    Minarik, David; Senneby, Martin; Wollmer, Per

    2015-01-01

    Background The interpretation of myocardial perfusion scintigraphy (MPS) largely relies on visual assessment by the physician of the localization and extent of a perfusion defect. The aim of this study was to introduce the concept of the perfusion vector as a new objective quantitative method...... for further assisting the visual interpretation and to test the concept using simulated MPS images as well as patients. Methods The perfusion vector is based on calculating the difference between the anatomical centroid and the perfusion center of gravity of the left ventricle. Simulated MPS images were.......001) but not for patients with infarction. The correlation between the defect size and stress vector magnitude was also found to be significant (p assisting the visual interpretation in MPS studies. Further...

  10. Simulated settings; powerful arenas for learning patient safety practices and facilitating transference to clinical practice. A mixed method study.

    Science.gov (United States)

    Reime, Marit Hegg; Johnsgaard, Tone; Kvam, Fred Ivan; Aarflot, Morten; Breivik, Marit; Engeberg, Janecke Merethe; Brattebø, Guttorm

    2016-11-01

    Poor teamwork is an important factor in the occurrence of critical incidents because of a lack of non-technical skills. Team training can be a key to prevent these incidents. The purpose of this study was to explore the experience of nursing and medical students after a simulation-based interprofessional team training (SBITT) course and its impact on professional and patient safety practices, using a concurrent mixed-method design. The participants (n = 262) were organized into 44 interprofessional teams. The results showed that two training sequences the same day improved overall team performance. Making mistakes during SBITT appeared to improve the quality of patient care once the students returned to clinical practice as it made the students more vigilant. Furthermore, the video-assisted oral debriefing provided an opportunity to strengthen interprofessional teamwork and share situational awareness. SBITT gave the students an opportunity to practice clinical reasoning skills and to share professional knowledge. The students conveyed the importance of learning to speak up to ensure safe patient practices. Simulated settings seem to be powerful arenas for learning patient safety practices and facilitating transference of this awareness to clinical practice. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. The impact of web-based and face-to-face simulation on patient deterioration and patient safety: protocol for a multi-site multi-method design.

    Science.gov (United States)

    Cooper, Simon J; Kinsman, Leigh; Chung, Catherine; Cant, Robyn; Boyle, Jayne; Bull, Loretta; Cameron, Amanda; Connell, Cliff; Kim, Jeong-Ah; McInnes, Denise; McKay, Angela; Nankervis, Katrina; Penz, Erika; Rotter, Thomas

    2016-09-07

    There are international concerns in relation to the management of patient deterioration which has led to a body of evidence known as the 'failure to rescue' literature. Nursing staff are known to miss cues of deterioration and often fail to call for assistance. Medical Emergency Teams (Rapid Response Teams) do improve the management of acutely deteriorating patients, but first responders need the requisite skills to impact on patient safety. In this study we aim to address these issues in a mixed methods interventional trial with the objective of measuring and comparing the cost and clinical impact of face-to-face and web-based simulation programs on the management of patient deterioration and related patient outcomes. The education programs, known as 'FIRST(2)ACT', have been found to have an impact on education and will be tested in four hospitals in the State of Victoria, Australia. Nursing staff will be trained in primary (the first 8 min) responses to emergencies in two medical wards using a face-to-face approach and in two medical wards using a web-based version FIRST(2)ACTWeb. The impact of these interventions will be determined through quantitative and qualitative approaches, cost analyses and patient notes review (time series analyses) to measure quality of care and patient outcomes. In this 18 month study it is hypothesised that both simulation programs will improve the detection and management of deteriorating patients but that the web-based program will have lower total costs. The study will also add to our overall understanding of the utility of simulation approaches in the preparation of nurses working in hospital wards. (ACTRN12616000468426, retrospectively registered 8.4.2016).

  12. Comparison of standardized patients with high-fidelity simulators for managing stress and improving performance in clinical deterioration: A mixed methods study.

    Science.gov (United States)

    Ignacio, Jeanette; Dolmans, Diana; Scherpbier, Albert; Rethans, Jan-Joost; Chan, Sally; Liaw, Sok Ying

    2015-12-01

    The use of standardized patients in deteriorating patient simulations adds realism that can be valuable for preparing nurse trainees for stress and enhancing their performance during actual patient deterioration. Emotional engagement resulting from increased fidelity can provide additional stress for student nurses with limited exposure to real patients. To determine the presence of increased stress with the standardized patient modality, this study compared the use of standardized patients (SP) with the use of high-fidelity simulators (HFS) during deteriorating patient simulations. Performance in managing deteriorating patients was also compared. It also explored student nurses' insights on the use of standardized patients and patient simulators in deteriorating patient simulations as preparation for clinical placement. Fifty-seven student nurses participated in a randomized controlled design study with pre- and post-tests to evaluate stress and performance in deteriorating patient simulations. Performance was assessed using the Rescuing A Patient in Deteriorating Situations (RAPIDS) rating tool. Stress was measured using salivary alpha-amylase levels. Fourteen participants who joined the randomized controlled component then participated in focus group discussions that elicited their insights on SP use in patient deterioration simulations. Analysis of covariance (ANCOVA) results showed no significant difference (p=0.744) between the performance scores of the SP and HFS groups in managing deteriorating patients. Amylase levels were also not significantly different (p=0.317) between the two groups. Stress in simulation, awareness of patient interactions, and realism were the main themes that resulted from the thematic analysis. Performance and stress in deteriorating patient simulations with standardized patients did not vary from similar simulations using high-fidelity patient simulators. Data from focus group interviews, however, suggested that the use of

  13. Patient Simulators Train Emergency Caregivers

    Science.gov (United States)

    2014-01-01

    Johnson Space Center teamed up with Sarasota, Florida-based METI (now CAE Healthcare) through the STTR program to ruggedize the company’s patient simulators for training astronauts in microgravity environments. The design modifications were implemented in future patient simulators that are now used to train first responders in the US military as well as fire departments and other agencies that work in disaster zones.

  14. Improving patient safety through better teamwork: how effective are different methods of simulation debriefing? Protocol for a pragmatic, prospective and randomised study.

    Science.gov (United States)

    Freytag, Julia; Stroben, Fabian; Hautz, Wolf E; Eisenmann, Dorothea; Kämmer, Juliane E

    2017-06-30

    Medical errors have an incidence of 9% and may lead to worse patient outcome. Teamwork training has the capacity to significantly reduce medical errors and therefore improve patient outcome. One common framework for teamwork training is crisis resource management, adapted from aviation and usually trained in simulation settings. Debriefing after simulation is thought to be crucial to learning teamwork-related concepts and behaviours but it remains unclear how best to debrief these aspects. Furthermore, teamwork-training sessions and studies examining education effects on undergraduates are rare. The study aims to evaluate the effects of two teamwork-focused debriefings on team performance after an extensive medical student teamwork training. A prospective experimental study has been designed to compare a well-established three-phase debriefing method (gather-analyse-summarise; the GAS method ) to a newly developed and more structured debriefing approach that extends the GAS method with TeamTAG (teamwork techniques analysis grid). TeamTAG is a cognitive aid listing preselected teamwork principles and descriptions of behavioural anchors that serve as observable patterns of teamwork and is supposed to help structure teamwork-focused debriefing. Both debriefing methods will be tested during an emergency room teamwork-training simulation comprising six emergency medicine cases faced by 35 final-year medical students in teams of five. Teams will be randomised into the two debriefing conditions. Team performance during simulation and the number of principles discussed during debriefing will be evaluated. Learning opportunities, helpfulness and feasibility will be rated by participants and instructors. Analyses will include descriptive, inferential and explorative statistics. The study protocol was approved by the institutional office for data protection and the ethics committee of Charité Medical School Berlin and registered under EA2/172/16. All students will

  15. Advancing renal education: hybrid simulation, using simulated patients to enhance realism in haemodialysis education.

    Science.gov (United States)

    Dunbar-Reid, Kylie; Sinclair, Peter M; Hudson, Denis

    2015-06-01

    Simulation is a well-established and proven teaching method, yet its use in renal education is not widely reported. Criticisms of simulation-based teaching include limited realism and a lack of authentic patient interaction. This paper discusses the benefits and challenges of high-fidelity simulation and suggests hybrid simulation as a complementary model to existing simulation programmes. Through the use of a simulated patient, hybrid simulation can improve the authenticity of renal simulation-based education while simultaneously teaching and assessing technologically enframed caring. © 2015 European Dialysis and Transplant Nurses Association/European Renal Care Association.

  16. Validation of a new method for testing provider clinical quality in rural settings in low- and middle-income countries: the observed simulated patient.

    Directory of Open Access Journals (Sweden)

    Tin Aung

    Full Text Available BACKGROUND: Assessing the quality of care provided by individual health practitioners is critical to identifying possible risks to the health of the public. However, existing assessment methods can be inaccurate, expensive, or infeasible in many developing country settings, particularly in rural areas and especially for children. Following an assessment of the strengths and weaknesses of the existing methods for provider assessment, we developed a synthesis method combining components of direct observation, clinical vignettes, and medical mannequins which we have termed "Observed Simulated Patient" or OSP. An OSP assessment involves a trained actor playing the role of a 'mother', a life-size doll representing a 5-year old boy, and a trained observer. The provider being assessed was informed in advance of the role-playing, and told to conduct the diagnosis and treatment as he normally would while verbally describing the examinations. METHODOLOGY/PRINCIPAL FINDINGS: We tested the validity of OSP by conducting parallel scoring of medical providers in Myanmar, assessing the quality of their diagnosis and treatment of pediatric malaria, first by direct observation of true patients and second by OSP. Data were collected from 20 private independent medical practitioners in Mon and Kayin States, Myanmar between December 26, 2010 and January 12, 2011. All areas of assessment showed agreement between OSP and direct observation above 90% except for history taking related to past experience with malaria medicines. In this area, providers did not ask questions of the OSP to the same degree that they questioned real patients (agreement 82.8%. CONCLUSIONS/SIGNIFICANCE: The OSP methodology may provide a valuable option for quality assessment of providers in places, or for health conditions, where other assessment tools are unworkable.

  17. Validation of a new method for testing provider clinical quality in rural settings in low- and middle-income countries: the observed simulated patient.

    Science.gov (United States)

    Aung, Tin; Montagu, Dominic; Schlein, Karen; Khine, Thin Myat; McFarland, Willi

    2012-01-01

    Assessing the quality of care provided by individual health practitioners is critical to identifying possible risks to the health of the public. However, existing assessment methods can be inaccurate, expensive, or infeasible in many developing country settings, particularly in rural areas and especially for children. Following an assessment of the strengths and weaknesses of the existing methods for provider assessment, we developed a synthesis method combining components of direct observation, clinical vignettes, and medical mannequins which we have termed "Observed Simulated Patient" or OSP. An OSP assessment involves a trained actor playing the role of a 'mother', a life-size doll representing a 5-year old boy, and a trained observer. The provider being assessed was informed in advance of the role-playing, and told to conduct the diagnosis and treatment as he normally would while verbally describing the examinations. We tested the validity of OSP by conducting parallel scoring of medical providers in Myanmar, assessing the quality of their diagnosis and treatment of pediatric malaria, first by direct observation of true patients and second by OSP. Data were collected from 20 private independent medical practitioners in Mon and Kayin States, Myanmar between December 26, 2010 and January 12, 2011. All areas of assessment showed agreement between OSP and direct observation above 90% except for history taking related to past experience with malaria medicines. In this area, providers did not ask questions of the OSP to the same degree that they questioned real patients (agreement 82.8%). The OSP methodology may provide a valuable option for quality assessment of providers in places, or for health conditions, where other assessment tools are unworkable.

  18. Patients with Chronic Conditions: Simulate to Educate?

    Science.gov (United States)

    Lefèvre, Thomas; Gagnayre, Rémi; Gignon, Maxime

    2017-01-01

    Simulation in healthcare in an way to train professionals but it is not yet use commonly to train patient or their caregivers. Recently, it has been suggested to extend simulations to patients with chronic conditions. Simulations could help patients and caregivers to acquire psychosocial and self-management skills. This approach proved to be…

  19. Methods for Monte Carlo simulations of biomacromolecules.

    Science.gov (United States)

    Vitalis, Andreas; Pappu, Rohit V

    2009-01-01

    The state-of-the-art for Monte Carlo (MC) simulations of biomacromolecules is reviewed. Available methodologies for sampling conformational equilibria and associations of biomacromolecules in the canonical ensemble, given a continuum description of the solvent environment, are reviewed. Detailed sections are provided dealing with the choice of degrees of freedom, the efficiencies of MC algorithms and algorithmic peculiarities, as well as the optimization of simple movesets. The issue of introducing correlations into elementary MC moves, and the applicability of such methods to simulations of biomacromolecules is discussed. A brief discussion of multicanonical methods and an overview of recent simulation work highlighting the potential of MC methods are also provided. It is argued that MC simulations, while underutilized biomacromolecular simulation community, hold promise for simulations of complex systems and phenomena that span multiple length scales, especially when used in conjunction with implicit solvation models or other coarse graining strategies.

  20. Using a simulated patient to transfer patient-centred skills from simulated practice to real patients in practice

    Directory of Open Access Journals (Sweden)

    Yolinda Uys

    2014-02-01

    Full Text Available Background: Simulation in healthcare education is common practice. Although this teaching strategy increases patient safety, it is not proven to enhance patient-centred care in practice. Simulated patients are used to teach communication skills and to contribute to the authenticity of the simulation. Could this enhanced authenticity help bridge the gap from simulated practice to practice with live patients where patient-centredness is of crucial importance? Objective: This study’s objective was to determine whether students who acquired a skill in simulation using a simulated patient displayed more patient-centredness in practice than students who used a mannikin. Method: A pre-experimental, post-test-only design with a comparison group was used. The population sample comprised all second-year B.Cur. students (N = 36 at a tertiary institution,who were divided into two cohorts. Cohort 1 was trained to administer an intramuscular injection using a simulated patient with a strap-on injectable device, whilst cohort 2 used an injection model. All participants were assessed on their procedural skills as well as patient centred care whilst administering an injection to a patient in hospital. A comparison was made of mean scores for patient-centred care rendered by the two cohorts. Results: Fisher’s exact test revealed that the mean score for patient-centredness of cohort 1 (88% was significantly higher (p = < 0.001 than that of cohort 2 (74%. Conclusion: Using a simulated patient to teach administration of an intramuscular injection enhanced students’ patient-centredness when performing the procedure in practice. Recommendations include making use of a bigger sample and including a pre-test the next time research of this nature is carried out.

  1. Detector Simulation: Data Treatment and Analysis Methods

    CERN Document Server

    Apostolakis, J

    2011-01-01

    Detector Simulation in 'Data Treatment and Analysis Methods', part of 'Landolt-Börnstein - Group I Elementary Particles, Nuclei and Atoms: Numerical Data and Functional Relationships in Science and Technology, Volume 21B1: Detectors for Particles and Radiation. Part 1: Principles and Methods'. This document is part of Part 1 'Principles and Methods' of Subvolume B 'Detectors for Particles and Radiation' of Volume 21 'Elementary Particles' of Landolt-Börnstein - Group I 'Elementary Particles, Nuclei and Atoms'. It contains the Section '4.1 Detector Simulation' of Chapter '4 Data Treatment and Analysis Methods' with the content: 4.1 Detector Simulation 4.1.1 Overview of simulation 4.1.1.1 Uses of detector simulation 4.1.2 Stages and types of simulation 4.1.2.1 Tools for event generation and detector simulation 4.1.2.2 Level of simulation and computation time 4.1.2.3 Radiation effects and background studies 4.1.3 Components of detector simulation 4.1.3.1 Geometry modeling 4.1.3.2 External fields 4.1.3.3 Intro...

  2. Isogeometric methods for numerical simulation

    CERN Document Server

    Bordas, Stéphane

    2015-01-01

    The book presents the state of the art in isogeometric modeling and shows how the method has advantaged. First an introduction to geometric modeling with NURBS and T-splines is given followed by the implementation into computer software. The implementation in both the FEM and BEM is discussed.

  3. Large-Eddy Simulation and Multigrid Methods

    Energy Technology Data Exchange (ETDEWEB)

    Falgout,R D; Naegle,S; Wittum,G

    2001-06-18

    A method to simulate turbulent flows with Large-Eddy Simulation on unstructured grids is presented. Two kinds of dynamic models are used to model the unresolved scales of motion and are compared with each other on different grids. Thereby the behavior of the models is shown and additionally the feature of adaptive grid refinement is investigated. Furthermore the parallelization aspect is addressed.

  4. 2-d Simulations of Test Methods

    DEFF Research Database (Denmark)

    Thrane, Lars Nyholm

    2004-01-01

    using both a Newton and Bingham model for characterisation of the rheological properties of the concrete. From the results, it is expected that both the slump flow and L-box can be simulated quite accurately when the model is extended to 3-d and the concrete is characterised according to the Bingham......One of the main obstacles for the further development of self-compacting concrete is to relate the fresh concrete properties to the form filling ability. Therefore, simulation of the form filling ability will provide a powerful tool in obtaining this goal. In this paper, a continuum mechanical...... approach is presented by showing initial results from 2-d simulations of the empirical test methods slump flow and L-box. This method assumes a homogeneous material, which is expected to correspond to particle suspensions e.g. concrete, when it remains stable. The simulations have been carried out when...

  5. Rainfall Simulation: methods, research questions and challenges

    Science.gov (United States)

    Ries, J. B.; Iserloh, T.

    2012-04-01

    In erosion research, rainfall simulations are used for the improvement of process knowledge as well as in the field for the assessment of overland flow generation, infiltration, and erosion rates. In all these fields of research, rainfall experiments have become an indispensable part of the research methods. In this context, small portable rainfall simulators with small test-plot sizes of one square-meter or even less, and devices of low weight and water consumption are in demand. Accordingly, devices with manageable technical effort like nozzle-type simulators seem to prevail against larger simulators. The reasons are obvious: lower costs and less time consumption needed for mounting enable a higher repetition rate. Regarding the high number of research questions, of different fields of application, and not least also due to the great technical creativity of our research staff, a large number of different experimental setups is available. Each of the devices produces a different rainfall, leading to different kinetic energy amounts influencing the soil surface and accordingly, producing different erosion results. Hence, important questions contain the definition, the comparability, the measurement and the simulation of natural rainfall and the problem of comparability in general. Another important discussion topic will be the finding of an agreement on an appropriate calibration method for the simulated rainfalls, in order to enable a comparison of the results of different rainfall simulator set-ups. In most of the publications, only the following "nice" sentence can be read: "Our rainfall simulator generates a rainfall spectrum that is similar to natural rainfall!". The most substantial and critical properties of a simulated rainfall are the drop-size distribution, the fall velocities of the drops, and the spatial distribution of the rainfall on the plot-area. In a comparison of the most important methods, the Laser Distrometer turned out to be the most up

  6. Matrix method for acoustic levitation simulation.

    Science.gov (United States)

    Andrade, Marco A B; Perez, Nicolas; Buiochi, Flavio; Adamowski, Julio C

    2011-08-01

    A matrix method is presented for simulating acoustic levitators. A typical acoustic levitator consists of an ultrasonic transducer and a reflector. The matrix method is used to determine the potential for acoustic radiation force that acts on a small sphere in the standing wave field produced by the levitator. The method is based on the Rayleigh integral and it takes into account the multiple reflections that occur between the transducer and the reflector. The potential for acoustic radiation force obtained by the matrix method is validated by comparing the matrix method results with those obtained by the finite element method when using an axisymmetric model of a single-axis acoustic levitator. After validation, the method is applied in the simulation of a noncontact manipulation system consisting of two 37.9-kHz Langevin-type transducers and a plane reflector. The manipulation system allows control of the horizontal position of a small levitated sphere from -6 mm to 6 mm, which is done by changing the phase difference between the two transducers. The horizontal position of the sphere predicted by the matrix method agrees with the horizontal positions measured experimentally with a charge-coupled device camera. The main advantage of the matrix method is that it allows simulation of non-symmetric acoustic levitators without requiring much computational effort.

  7. A SIMULATION ON TEACHING VOLHARD METHOD

    Directory of Open Access Journals (Sweden)

    Celal BAYRAK

    2009-07-01

    Full Text Available Laboratories are important components of chemistry education. Virtual simulations allow students to repeat the experiments as many times as they want and give students the opportunity to learn in their own ways. In this study, a computer assisted teaching material has been developed for tertiary level. This material has been planned to use in Analytical Chemistry Course content in the subject of quantitative methods. This teaching material has been developed by using Flash program and consisted of animations and simulations related to the quantitative determination of chloride by Volhard Method. Even though the quantitative determination of chloride by Volhard Method could be conducted in the laboratory setting, this experiment has been prepared by using simulations to give students the opportunity to repeat the experiment steps when they want, to control the each step, observing the changes on the equivalence point better. Volhard method is one of the methods to be considered as important in chemistry courses and laboratories. It is an important practical experience for students in the laboratory. In this study, the presented simulation has been prepared by considering these harmful effects and insufficient laboratory conditions.

  8. Hybrid Method Simulation of Slender Marine Structures

    DEFF Research Database (Denmark)

    Christiansen, Niels Hørbye

    This present thesis consists of an extended summary and five appended papers concerning various aspects of the implementation of a hybrid method which combines classical simulation methods and artificial neural networks. The thesis covers three main topics. Common for all these topics...... is that they deal with time domain simulation of slender marine structures such as mooring lines and flexible risers used in deep sea offshore installations. The first part of the thesis describes how neural networks can be designed and trained to cover a large number of different sea states. Neural networks can...... to simulate dynamic response of specific critical hot spots on a flexible riser. In the design of mooring lines only top tension forces are considered. These forces can easily be determined by a single neural network. Riser design, depending on the applied configuration, requires detailed analysis of several...

  9. Simulation teaching method in Engineering Optics

    Science.gov (United States)

    Lu, Qieni; Wang, Yi; Li, Hongbin

    2017-08-01

    We here introduce a pedagogical method of theoretical simulation as one major means of the teaching process of "Engineering Optics" in course quality improvement action plan (Qc) in our school. Students, in groups of three to five, complete simulations of interference, diffraction, electromagnetism and polarization of light; each student is evaluated and scored in light of his performance in the interviews between the teacher and the student, and each student can opt to be interviewed many times until he is satisfied with his score and learning. After three years of Qc practice, the remarkable teaching and learning effect is obatined. Such theoretical simulation experiment is a very valuable teaching method worthwhile for physical optics which is highly theoretical and abstruse. This teaching methodology works well in training students as to how to ask questions and how to solve problems, which can also stimulate their interest in research learning and their initiative to develop their self-confidence and sense of innovation.

  10. Method for Constructing Standardized Simulated Root Canals.

    Science.gov (United States)

    Schulz-Bongert, Udo; Weine, Franklin S.

    1990-01-01

    The construction of visual and manipulative aids, clear resin blocks with root-canal-like spaces, for simulation of root canals is explained. Time, materials, and techniques are discussed. The method allows for comparison of canals, creation of any configuration of canals, and easy presentation during instruction. (MSE)

  11. Metropolis Methods for Quantum Monte Carlo Simulations

    OpenAIRE

    Ceperley, D.M.

    2003-01-01

    Since its first description fifty years ago, the Metropolis Monte Carlo method has been used in a variety of different ways for the simulation of continuum quantum many-body systems. This paper will consider some of the generalizations of the Metropolis algorithm employed in quantum Monte Carlo: Variational Monte Carlo, dynamical methods for projector monte carlo ({\\it i.e.} diffusion Monte Carlo with rejection), multilevel sampling in path integral Monte Carlo, the sampling of permutations, ...

  12. An Efficient Simulation Method for Rare Events

    KAUST Repository

    Rached, Nadhir B.

    2015-01-07

    Estimating the probability that a sum of random variables (RVs) exceeds a given threshold is a well-known challenging problem. Closed-form expressions for the sum distribution do not generally exist, which has led to an increasing interest in simulation approaches. A crude Monte Carlo (MC) simulation is the standard technique for the estimation of this type of probability. However, this approach is computationally expensive, especially when dealing with rare events. Variance reduction techniques are alternative approaches that can improve the computational efficiency of naive MC simulations. We propose an Importance Sampling (IS) simulation technique based on the well-known hazard rate twisting approach, that presents the advantage of being asymptotically optimal for any arbitrary RVs. The wide scope of applicability of the proposed method is mainly due to our particular way of selecting the twisting parameter. It is worth observing that this interesting feature is rarely satisfied by variance reduction algorithms whose performances were only proven under some restrictive assumptions. It comes along with a good efficiency, illustrated by some selected simulation results comparing the performance of our method with that of an algorithm based on a conditional MC technique.

  13. The impact of repeated simulation on health and healthcare perceptions of simulated patients.

    NARCIS (Netherlands)

    Boerjan, M.; Boone, F.; Anthierens, S.; Weel-Baumgarten, E.M. van; Deveugele, M.

    2008-01-01

    OBJECTIVE: To explore the effect of simulating medical conditions on simulated patients (SPs). Main points of interest are influence on: perception of personal health and perception of their relation with the health care provider (HCP), personal well being. METHODS: Semi-structured interviews were

  14. Haemodynamic imaging of thoracic stent-grafts by computational fluid dynamics (CFD): presentation of a patient-specific method combining magnetic resonance imaging and numerical simulations.

    Science.gov (United States)

    Midulla, Marco; Moreno, Ramiro; Baali, Adil; Chau, Ming; Negre-Salvayre, Anne; Nicoud, Franck; Pruvo, Jean-Pierre; Haulon, Stephan; Rousseau, Hervé

    2012-10-01

    In the last decade, there was been increasing interest in finding imaging techniques able to provide a functional vascular imaging of the thoracic aorta. The purpose of this paper is to present an imaging method combining magnetic resonance imaging (MRI) and computational fluid dynamics (CFD) to obtain a patient-specific haemodynamic analysis of patients treated by thoracic endovascular aortic repair (TEVAR). MRI was used to obtain boundary conditions. MR angiography (MRA) was followed by cardiac-gated cine sequences which covered the whole thoracic aorta. Phase contrast imaging provided the inlet and outlet profiles. A CFD mesh generator was used to model the arterial morphology, and wall movements were imposed according to the cine imaging. CFD runs were processed using the finite volume (FV) method assuming blood as a homogeneous Newtonian fluid. Twenty patients (14 men; mean age 62.2 years) with different aortic lesions were evaluated. Four-dimensional mapping of velocity and wall shear stress were obtained, depicting different patterns of flow (laminar, turbulent, stenosis-like) and local alterations of parietal stress in-stent and along the native aorta. A computational method using a combined approach with MRI appears feasible and seems promising to provide detailed functional analysis of thoracic aorta after stent-graft implantation. • Functional vascular imaging of the thoracic aorta offers new diagnostic opportunities • CFD can model vascular haemodynamics for clinical aortic problems • Combining CFD with MRI offers patient specific method of aortic analysis • Haemodynamic analysis of stent-grafts could improve clinical management and follow-up.

  15. Simulation and the Monte Carlo method

    CERN Document Server

    Rubinstein, Reuven Y

    2016-01-01

    Simulation and the Monte Carlo Method, Third Edition reflects the latest developments in the field and presents a fully updated and comprehensive account of the major topics that have emerged in Monte Carlo simulation since the publication of the classic First Edition over more than a quarter of a century ago. While maintaining its accessible and intuitive approach, this revised edition features a wealth of up-to-date information that facilitates a deeper understanding of problem solving across a wide array of subject areas, such as engineering, statistics, computer science, mathematics, and the physical and life sciences. The book begins with a modernized introduction that addresses the basic concepts of probability, Markov processes, and convex optimization. Subsequent chapters discuss the dramatic changes that have occurred in the field of the Monte Carlo method, with coverage of many modern topics including: Markov Chain Monte Carlo, variance reduction techniques such as the transform likelihood ratio...

  16. Twitter's tweet method modelling and simulation

    Science.gov (United States)

    Sarlis, Apostolos S.; Sakas, Damianos P.; Vlachos, D. S.

    2015-02-01

    This paper seeks to purpose the concept of Twitter marketing methods. The tools that Twitter provides are modelled and simulated using iThink in the context of a Twitter media-marketing agency. The paper has leveraged the system's dynamic paradigm to conduct Facebook marketing tools and methods modelling, using iThink™ system to implement them. It uses the design science research methodology for the proof of concept of the models and modelling processes. The following models have been developed for a twitter marketing agent/company and tested in real circumstances and with real numbers. These models were finalized through a number of revisions and iterators of the design, develop, simulate, test and evaluate. It also addresses these methods that suit most organized promotion through targeting, to the Twitter social media service. The validity and usefulness of these Twitter marketing methods models for the day-to-day decision making are authenticated by the management of the company organization. It implements system dynamics concepts of Twitter marketing methods modelling and produce models of various Twitter marketing situations. The Tweet method that Twitter provides can be adjusted, depending on the situation, in order to maximize the profit of the company/agent.

  17. Multigrid methods with applications to reservoir simulation

    Energy Technology Data Exchange (ETDEWEB)

    Xiao, Shengyou [Univ. of Texas, Austin, TX (United States)

    1994-05-01

    Multigrid methods are studied for solving elliptic partial differential equations. Focus is on parallel multigrid methods and their use for reservoir simulation. Multicolor Fourier analysis is used to analyze the behavior of standard multigrid methods for problems in one and two dimensions. Relation between multicolor and standard Fourier analysis is established. Multiple coarse grid methods for solving model problems in 1 and 2 dimensions are considered; at each coarse grid level we use more than one coarse grid to improve convergence. For a given Dirichlet problem, a related extended problem is first constructed; a purification procedure can be used to obtain Moore-Penrose solutions of the singular systems encountered. For solving anisotropic equations, semicoarsening and line smoothing techniques are used with multiple coarse grid methods to improve convergence. Two-level convergence factors are estimated using multicolor. In the case where each operator has the same stencil on each grid point on one level, exact multilevel convergence factors can be obtained. For solving partial differential equations with discontinuous coefficients, interpolation and restriction operators should include information about the equation coefficients. Matrix-dependent interpolation and restriction operators based on the Schur complement can be used in nonsymmetric cases. A semicoarsening multigrid solver with these operators is used in UTCOMP, a 3-D, multiphase, multicomponent, compositional reservoir simulator. The numerical experiments are carried out on different computing systems. Results indicate that the multigrid methods are promising.

  18. A SIMULATION ON TEACHING VOLHARD METHOD

    OpenAIRE

    BAYRAK, CELAL; Nilgün SECKEN; Funda OZCAN OZTURK; Evrim URAL ALSAN

    2009-01-01

    Laboratories are important components of chemistry education. Virtual simulations allow students to repeat the experiments as many times as they want and give students the opportunity to learn in their own ways. In this study, a computer assisted teaching material has been developed for tertiary level. This material has been planned to use in Analytical Chemistry Course content in the subject of quantitative methods. This teaching material has been developed by using Flash program and consist...

  19. Electromagnetic simulation using the FDTD method

    CERN Document Server

    Sullivan, Dennis M

    2013-01-01

    A straightforward, easy-to-read introduction to the finite-difference time-domain (FDTD) method Finite-difference time-domain (FDTD) is one of the primary computational electrodynamics modeling techniques available. Since it is a time-domain method, FDTD solutions can cover a wide frequency range with a single simulation run and treat nonlinear material properties in a natural way. Written in a tutorial fashion, starting with the simplest programs and guiding the reader up from one-dimensional to the more complex, three-dimensional programs, this book provides a simple, yet comp

  20. Spectral Methods in Numerical Plasma Simulation

    DEFF Research Database (Denmark)

    Coutsias, E.A.; Hansen, F.R.; Huld, T.

    1989-01-01

    An introduction is given to the use of spectral methods in numerical plasma simulation. As examples of the use of spectral methods, solutions to the two-dimensional Euler equations in both a simple, doubly periodic region, and on an annulus will be shown. In the first case, the solution is expanded...... in a two-dimensional Fourier series, while a Chebyshev-Fourier expansion is employed in the second case. A new, efficient algorithm for the solution of Poisson's equation on an annulus is introduced. Problems connected to aliasing and to short wavelength noise generated by gradient steepening are discussed....

  1. Simulating marine propellers with vortex particle method

    Science.gov (United States)

    Wang, Youjiang; Abdel-Maksoud, Moustafa; Song, Baowei

    2017-01-01

    The vortex particle method is applied to compute the open water characteristics of marine propellers. It is based on the large-eddy simulation technique, and the Smagorinsky-Lilly sub-grid scale model is implemented for the eddy viscosity. The vortex particle method is combined with the boundary element method, in the sense that the body is modelled with boundary elements and the slipstream is modelled with vortex particles. Rotational periodic boundaries are adopted, which leads to a cylindrical sector domain for the slipstream. The particle redistribution scheme and the fast multipole method are modified to consider the rotational periodic boundaries. Open water characteristics of three propellers with different skew angles are calculated with the proposed method. The results are compared with the ones obtained with boundary element method and experiments. It is found that the proposed method predicts the open water characteristics more accurately than the boundary element method, especially for high loading condition and high skew propeller. The influence of the Smagorinsky constant is also studied, which shows the results have a low sensitivity to it.

  2. Using "think aloud" to capture clinical reasoning during patient simulation.

    Science.gov (United States)

    Burbach, Beth; Barnason, Susan; Thompson, Sarah A

    2015-02-03

    Think Aloud (TA), a strategy in which subjects are instructed to verbalize thoughts as they occur while completing an assigned task, was integrated into a study of clinical reasoning during high fidelity patient simulation by baccalaureate nursing students. TA methods in nursing education research with patient simulation have not previously been reported. Concurrent TA (verbalization of thoughts in short-term memory) and retrospective TA (reflective thoughts verbalized during an immediate post-simulation interview) methods facilitated the collection of rich and meaningful data. Students demonstrated distinct patterns in verbalization during concurrent TA, including public and private thoughts, narration of care, and the use of the pause to facilitate clinical reasoning. Retrospective TA data provided rich descriptions of reflection-on-action. TA provides a rich source of data regarding clinical reasoning as experienced by the baccalaureate nursing student during high fidelity patient simulation.

  3. Scripting Scenarios for the Human Patient Simulator

    Science.gov (United States)

    Bacal, Kira; Miller, Robert; Doerr, Harold

    2004-01-01

    The Human Patient Simulator (HPS) is particularly useful in providing scenario-based learning which can be tailored to fit specific scenarios and which can be modified in realtime to enhance the teaching environment. Scripting these scenarios so as to maximize learning requires certain skills, in order to ensure that a change in student performance, understanding, critical thinking, and/or communication skills results. Methods: A "good" scenario can be defined in terms of applicability, learning opportunities, student interest, and clearly associated metrics. Obstacles to such a scenario include a lack of understanding of the applicable environment by the scenario author(s), a desire (common among novices) to cover too many topics, failure to define learning objectives, mutually exclusive or confusing learning objectives, unskilled instructors, poor preparation , disorganized approach, or an inappropriate teaching philosophy (such as "trial by fire" or education through humiliation). Results: Descriptions of several successful teaching programs, used in the military, civilian, and NASA medical environments , will be provided, along with sample scenarios. Discussion: Simulator-based lessons have proven to be a time- and cost-efficient manner by which to educate medical personnel. Particularly when training for medical care in austere environments (pre-hospital, aeromedical transport, International Space Station, military operations), the HPS can enhance the learning experience.

  4. Nursing Student Anxiety in Simulation Settings: A Mixed Methods Study

    Science.gov (United States)

    Cato, Mary Louise

    2013-01-01

    The use of simulation as a clinical learning activity is growing in nursing programs across the country. Using simulation, educators can provide students with a realistic patient situation using mannequins or actors as patients in a simulated environment. Students can practice multiple aspects of patient care without the risk of making mistakes…

  5. Combining building thermal simulation methods and LCA methods

    DEFF Research Database (Denmark)

    Pedersen, Frank; Hansen, Klaus; Wittchen, Kim Bjarne

    2008-01-01

    of buildings (as expressed in EU Directive 2002/91/EC), may in the future be supplemented by requirements to the environmental impact of buildings. This can be seen by the fact that EU recently has given EN mandate to prepare standards for environmental assessment of buildings (CEN/TC 350).......Thsi paper describes recent efforts made by the Danish Building Research Institute regarding the integration of a life cycle assessment (LCA) method into a whole building hygro-thermal simulation tool. The motivation for the work is that the increased requirements to the energy performance...

  6. Rare event simulation using Monte Carlo methods

    CERN Document Server

    Rubino, Gerardo

    2009-01-01

    In a probabilistic model, a rare event is an event with a very small probability of occurrence. The forecasting of rare events is a formidable task but is important in many areas. For instance a catastrophic failure in a transport system or in a nuclear power plant, the failure of an information processing system in a bank, or in the communication network of a group of banks, leading to financial losses. Being able to evaluate the probability of rare events is therefore a critical issue. Monte Carlo Methods, the simulation of corresponding models, are used to analyze rare events. This book sets out to present the mathematical tools available for the efficient simulation of rare events. Importance sampling and splitting are presented along with an exposition of how to apply these tools to a variety of fields ranging from performance and dependability evaluation of complex systems, typically in computer science or in telecommunications, to chemical reaction analysis in biology or particle transport in physics. ...

  7. Comparison Of Simulation Results When Using Two Different Methods For Mold Creation In Moldflow Simulation

    Directory of Open Access Journals (Sweden)

    Kaushikbhai C. Parmar

    2017-04-01

    Full Text Available Simulation gives different results when using different methods for the same simulation. Autodesk Moldflow Simulation software provide two different facilities for creating mold for the simulation of injection molding process. Mold can be created inside the Moldflow or it can be imported as CAD file. The aim of this paper is to study the difference in the simulation results like mold temperature part temperature deflection in different direction time for the simulation and coolant temperature for this two different methods.

  8. Management of Simulated Patients with Sexually Transmitted ...

    African Journals Online (AJOL)

    Management of Simulated Patients with Sexually Transmitted Infections by Staff of Retail Pharmacies in Kibera Slums Of Nairobi. ... to inappropriate or inadequate treatment. Recommendation: To improve management of these conditions, in-service training and enforcement of the relevant legislation and policy is needed.

  9. Simulated patient studies: an ethical analysis.

    Science.gov (United States)

    Rhodes, Karin V; Miller, Franklin G

    2012-12-01

    In connection with health care reform, the U.S. Department of Health and Human Services commissioned a "mystery shopper," or simulated patient study, to measure access to primary care. But the study was shelved because of public controversy over "government spying" on doctors. Opponents of the study also raised ethical concerns about the use of deception with human subjects without soliciting their informed consent. We undertook an ethical analysis of the use of simulated patient techniques in health services research, with a particular focus on research measuring access to care. Using a case study, we explored relevant methodological considerations and ethical principles relating to deceptive research without informed consent, as well as U.S. federal regulations permitting exceptions to consent. Several relevant considerations both favor and oppose soliciting consent for simulated patient studies. Making research participation conditional on informed consent protects the autonomy of research subjects and shields them from unreasonable exposure to research risks. However, scientific validity is also an important ethical principle of human subjects research, as the net risks to subjects must be justified by the value to society of the knowledge to be gained. The use of simulated patients to monitor access is a naturalistic and scientifically sound experimental design that can answer important policy-relevant questions, with minimal risks to human subjects. As interaction between researchers and subjects increases, however, so does the need for consent. As long as adequate protections of confidentiality of research data are in place, minimally intrusive simulated patient research that gathers policy-relevant data on the health system without the consent of individuals working in that system can be ethically justified when the risks and burdens to research subjects are minimal and the research has the potential to generate socially valuable knowledge. © 2012 Milbank

  10. Stochastic simulation and Monte-Carlo methods; Simulation stochastique et methodes de Monte-Carlo

    Energy Technology Data Exchange (ETDEWEB)

    Graham, C. [Centre National de la Recherche Scientifique (CNRS), 91 - Gif-sur-Yvette (France); Ecole Polytechnique, 91 - Palaiseau (France); Talay, D. [Institut National de Recherche en Informatique et en Automatique (INRIA), 78 - Le Chesnay (France); Ecole Polytechnique, 91 - Palaiseau (France)

    2011-07-01

    This book presents some numerical probabilistic methods of simulation with their convergence speed. It combines mathematical precision and numerical developments, each proposed method belonging to a precise theoretical context developed in a rigorous and self-sufficient manner. After some recalls about the big numbers law and the basics of probabilistic simulation, the authors introduce the martingales and their main properties. Then, they develop a chapter on non-asymptotic estimations of Monte-Carlo method errors. This chapter gives a recall of the central limit theorem and precises its convergence speed. It introduces the Log-Sobolev and concentration inequalities, about which the study has greatly developed during the last years. This chapter ends with some variance reduction techniques. In order to demonstrate in a rigorous way the simulation results of stochastic processes, the authors introduce the basic notions of probabilities and of stochastic calculus, in particular the essential basics of Ito calculus, adapted to each numerical method proposed. They successively study the construction and important properties of the Poisson process, of the jump and deterministic Markov processes (linked to transport equations), and of the solutions of stochastic differential equations. Numerical methods are then developed and the convergence speed results of algorithms are rigorously demonstrated. In passing, the authors describe the probabilistic interpretation basics of the parabolic partial derivative equations. Non-trivial applications to real applied problems are also developed. (J.S.)

  11. IMPROVING MANUFACTURING PROCESSES USING SIMULATION METHODS

    Directory of Open Access Journals (Sweden)

    Sławomir KŁOS

    2016-12-01

    Full Text Available The paper presents the results of simulation research on buffer space allocated in a flow line and operation times influence on the throughput of a manufacturing system. The production line in the study consists of four stages and is based on a real machining manufacturing system of a small production enterprise. Using Tecnomatix Plant Simulation software, a simulation model of the system was created and set of experiments was planned. Simulation experiments were prepared for different capacities of intermediate buffers located between manufacturing resources and operation times as input parameters, and the throughput per hour and average life span of products as the output.

  12. Methods and evaluations for simulation debriefing in nursing education.

    Science.gov (United States)

    Waznonis, Annette R

    2014-08-01

    Debriefing is the most important aspect of simulated learning, but actual debriefing practices are not evidence based or widely known. Expert opinions on effective simulation debriefing have been widely published and likely guide debriefing in nursing education. However, various terms are used to discuss simulation debriefing, making it difficult to distinguish debriefing methods. Also, the means for evaluating simulation debriefing are lacking. The purpose of this review is to identify and examine methods and evaluations for simulation debriefing in the educational setting. Twenty-two methods and seven evaluations for simulation debriefing were found. Four areas of differences among methods-suggested uses, design features, supplemental resources, and means for evaluation-were demonstrated. This review offers nurse educators and researchers a comprehensive, practical examination of the methods and evaluations for simulation debriefing in the educational setting, clarifies terminology, and describes how the debriefing methods, phases, approaches, elements, and evaluations are interrelated. Copyright 2014, SLACK Incorporated.

  13. Virtual Crowds Methods, Simulation, and Control

    CERN Document Server

    Pelechano, Nuria; Allbeck, Jan

    2008-01-01

    There are many applications of computer animation and simulation where it is necessary to model virtual crowds of autonomous agents. Some of these applications include site planning, education, entertainment, training, and human factors analysis for building evacuation. Other applications include simulations of scenarios where masses of people gather, flow, and disperse, such as transportation centers, sporting events, and concerts. Most crowd simulations include only basic locomotive behaviors possibly coupled with a few stochastic actions. Our goal in this survey is to establish a baseline o

  14. Numerical methods in simulation of resistance welding

    DEFF Research Database (Denmark)

    Nielsen, Chris Valentin; Martins, Paulo A.F.; Zhang, Wenqi

    2015-01-01

    Finite element simulation of resistance welding requires coupling betweenmechanical, thermal and electrical models. This paper presents the numerical models and theircouplings that are utilized in the computer program SORPAS. A mechanical model based onthe irreducible flow formulation is utilized...... a resistance welding point of view, the most essential coupling between the above mentioned models is the heat generation by electrical current due to Joule heating. The interaction between multiple objects is anothercritical feature of the numerical simulation of resistance welding because it influences...

  15. Simulation methods for bumper system development

    OpenAIRE

    Isaksson, Erik

    2006-01-01

    n development of bumper systems for the automotive industry, iterative Finite Element (FE) simulations are normally used to find a bumper design that meets the requirements of crash performance. The crash performance of a bumper system is normally verified by results from standardized low speed crash tests based on common crash situations. Consequently, these crash load cases are also used in the FE simulations during the development process. However, lack of data for the car under developmen...

  16. Bio-imaging and visualization for patient-customized simulations

    CERN Document Server

    Luo, Xiongbiao; Li, Shuo

    2014-01-01

    This book contains the full papers presented at the MICCAI 2013 workshop Bio-Imaging and Visualization for Patient-Customized Simulations (MWBIVPCS 2013). MWBIVPCS 2013 brought together researchers representing several fields, such as Biomechanics, Engineering, Medicine, Mathematics, Physics and Statistic. The contributions included in this book present and discuss new trends in those fields, using several methods and techniques, including the finite element method, similarity metrics, optimization processes, graphs, hidden Markov models, sensor calibration, fuzzy logic, data mining, cellular automation, active shape models, template matching and level sets. These serve as tools to address more efficiently different and timely applications involving signal and image acquisition, image processing and analysis, image segmentation, image registration and fusion, computer simulation, image based modelling, simulation and surgical planning, image guided robot assisted surgical and image based diagnosis.  This boo...

  17. Airway skills training using a human patient simulator | Moodley ...

    African Journals Online (AJOL)

    ... of airway management skills using the simulator. Participant satisfaction was much better in the simulator group. The importance of psychomotor reinforcement should be borne in mind when designing simulation courses. Keywords: human patient simulator, simulation, airway management, psychomotor skills ...

  18. A method for ensemble wildland fire simulation

    Science.gov (United States)

    Mark A. Finney; Isaac C. Grenfell; Charles W. McHugh; Robert C. Seli; Diane Trethewey; Richard D. Stratton; Stuart Brittain

    2011-01-01

    An ensemble simulation system that accounts for uncertainty in long-range weather conditions and two-dimensional wildland fire spread is described. Fuel moisture is expressed based on the energy release component, a US fire danger rating index, and its variation throughout the fire season is modeled using time series analysis of historical weather data. This analysis...

  19. High-order finite element methods for cardiac monodomain simulations

    Directory of Open Access Journals (Sweden)

    Kevin P Vincent

    2015-08-01

    Full Text Available Computational modeling of tissue-scale cardiac electrophysiology requires numerically converged solutions to avoid spurious artifacts. The steep gradients inherent to cardiac action potential propagation necessitate fine spatial scales and therefore a substantial computational burden. The use of high-order interpolation methods has previously been proposed for these simulations due to their theoretical convergence advantage. In this study, we compare the convergence behavior of linear Lagrange, cubic Hermite, and the newly proposed cubic Hermite-style serendipity interpolation methods for finite element simulations of the cardiac monodomain equation. The high-order methods reach converged solutions with fewer degrees of freedom and longer element edge lengths than traditional linear elements. Additionally, we propose a dimensionless number, the cell Thiele modulus, as a more useful metric for determining solution convergence than element size alone. Finally, we use the cell Thiele modulus to examine convergence criteria for obtaining clinically useful activation patterns for applications such as patient-specific modeling where the total activation time is known a priori.

  20. High-order finite element methods for cardiac monodomain simulations

    Science.gov (United States)

    Vincent, Kevin P.; Gonzales, Matthew J.; Gillette, Andrew K.; Villongco, Christopher T.; Pezzuto, Simone; Omens, Jeffrey H.; Holst, Michael J.; McCulloch, Andrew D.

    2015-01-01

    Computational modeling of tissue-scale cardiac electrophysiology requires numerically converged solutions to avoid spurious artifacts. The steep gradients inherent to cardiac action potential propagation necessitate fine spatial scales and therefore a substantial computational burden. The use of high-order interpolation methods has previously been proposed for these simulations due to their theoretical convergence advantage. In this study, we compare the convergence behavior of linear Lagrange, cubic Hermite, and the newly proposed cubic Hermite-style serendipity interpolation methods for finite element simulations of the cardiac monodomain equation. The high-order methods reach converged solutions with fewer degrees of freedom and longer element edge lengths than traditional linear elements. Additionally, we propose a dimensionless number, the cell Thiele modulus, as a more useful metric for determining solution convergence than element size alone. Finally, we use the cell Thiele modulus to examine convergence criteria for obtaining clinically useful activation patterns for applications such as patient-specific modeling where the total activation time is known a priori. PMID:26300783

  1. Interactive methods for exploring particle simulation data

    Energy Technology Data Exchange (ETDEWEB)

    Co, Christopher S.; Friedman, Alex; Grote, David P.; Vay, Jean-Luc; Bethel, E. Wes; Joy, Kenneth I.

    2004-05-01

    In this work, we visualize high-dimensional particle simulation data using a suite of scatter plot-based visualizations coupled with interactive selection tools. We use traditional 2D and 3D projection scatter plots as well as a novel oriented disk rendering style to convey various information about the data. Interactive selection tools allow physicists to manually classify ''interesting'' sets of particles that are highlighted across multiple, linked views of the data. The power of our application is the ability to correspond new visual representations of the simulation data with traditional, well understood visualizations. This approach supports the interactive exploration of the high-dimensional space while promoting discovery of new particle behavior.

  2. Hospital Registration Process Reengineering Using Simulation Method

    Directory of Open Access Journals (Sweden)

    Qiang Su

    2010-01-01

    Full Text Available With increasing competition, many healthcare organizations have undergone tremendous reform in the last decade aiming to increase efficiency, decrease waste, and reshape the way that care is delivered. This study focuses on the operational efficiency improvement of hospital’s registration process. The operational efficiency related factors including the service process, queue strategy, and queue parameters were explored systematically and illustrated with a case study. Guided by the principle of business process reengineering (BPR, a simulation approach was employed for process redesign and performance optimization. As a result, the queue strategy is changed from multiple queues and multiple servers to single queue and multiple servers with a prepare queue. Furthermore, through a series of simulation experiments, the length of the prepare queue and the corresponding registration process efficiency was quantitatively evaluated and optimized.

  3. TreePM Method for Two-Dimensional Cosmological Simulations

    Indian Academy of Sciences (India)

    TreePM Method for Two-Dimensional Cosmological Simulations. Suryadeep Ray ... Keywords. Gravitation; methods: numerical; cosmology: large scale structure of the universe. ... The 2d TreePM code is an accurate and efficient technique to carry out large two-dimensional N-body simulations in cosmology. This hybrid ...

  4. Simulation of tunneling construction methods of the Cisumdawu toll road

    Science.gov (United States)

    Abduh, Muhamad; Sukardi, Sapto Nugroho; Ola, Muhammad Rusdian La; Ariesty, Anita; Wirahadikusumah, Reini D.

    2017-11-01

    Simulation can be used as a tool for planning and analysis of a construction method. Using simulation technique, a contractor could design optimally resources associated with a construction method and compare to other methods based on several criteria, such as productivity, waste, and cost. This paper discusses the use of simulation using Norwegian Method of Tunneling (NMT) for a 472-meter tunneling work in the Cisumdawu Toll Road project. Primary and secondary data were collected to provide useful information for simulation as well as problems that may be faced by the contractor. The method was modelled using the CYCLONE and then simulated using the WebCYCLONE. The simulation could show the duration of the project from the duration model of each work tasks which based on literature review, machine productivity, and several assumptions. The results of simulation could also show the total cost of the project that was modeled based on journal construction & building unit cost and online websites of local and international suppliers. The analysis of the advantages and disadvantages of the method was conducted based on its, wastes, and cost. The simulation concluded the total cost of this operation is about Rp. 900,437,004,599 and the total duration of the tunneling operation is 653 days. The results of the simulation will be used for a recommendation to the contractor before the implementation of the already selected tunneling operation.

  5. Math-Based Simulation Tools and Methods

    National Research Council Canada - National Science Library

    Arepally, Sudhakar

    2007-01-01

    ...: HMMWV 30-mph Rollover Test, Soldier Gear Effects, Occupant Performance in Blast Effects, Anthropomorphic Test Device, Human Models, Rigid Body Modeling, Finite Element Methods, Injury Criteria...

  6. Comparing three methods for participatory simulation of hospital work systems

    DEFF Research Database (Denmark)

    Broberg, Ole; Andersen, Simone Nyholm

    Summative Statement: This study compared three participatory simulation methods using different simulation objects: Low resolution table-top setup using Lego figures, full scale mock-ups, and blueprints using Lego figures. It was concluded the three objects by differences in fidelity and affordance...... and why this influence took place. Research Objective / Question: How does the simulation object influence which elements of a work system are being evaluated in participatory simulation events? Methodology: Observation notes and video recordings of three types of simulation events using different objects...... simulation objects may to a certain degree influence what part of a work system is being addressed in participatory simulation events. For human factors practitioners in hospital design projects it is important to pay attention to this when planning and facilitating simulation events to evaluate different...

  7. Using simulation methods for orthopaedic implant design.

    Science.gov (United States)

    Rickey, L

    2009-09-01

    New virtual test methods are being used to better understand the functional performance of implants within the musculoskeletal system. Developing validated virtual models and tests reduces prototyping costs and compresses product development cycles.

  8. Cartesian Grid Method for Compressible Flow Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Farooq, Muhammed Asif

    2012-07-01

    The Cartesian grid method is an alternative to the existing methods to solve a physical problem governed by partial differential equations (PDEs) computationally. Researchers are interested in this method due to its simplicity of grid generation, less computational effort and ease of implementation into a computer code. One of the other options to solve a physical PDE problem is by the body-fitted grid method. In the body-fitted grid method, the boundary points are grid points. This is not the case with the Cartesian grid method where the body wall is embedded as a boundary into a Cartesian grid resulting in irregular cells near the embedded boundary. These irregular cells near the embedded boundary are known as cut-cells. Instead of using special treatments of the cut-cells or enforcing the presence of the embedded boundary by adding source terms at the Cartesian grid points near the boundary, the kinematic and other boundary conditions can be introduced in the Cartesian grid method via ghost points. Those grid points which lie inside the embedded boundary and are also a part of computation are called ghost points. Inactive grid points inside the embedded boundary are referred to as solid points. In the present Cartesian grid method, based on a ghost point treatment, local symmetry conditions are imposed at the embedded wall boundary. The ghost point treatments available in the literature are difficult to implement due to complex procedures. We are introducing a new approach to approximate the kinematics of the embedded boundary by a very simple ghost point treatment called the simplified ghost point treatment. In this approach, we consider the grid lines in the x- and y- directions as approximations of the lines normal to the embedded boundary depending on whether the angle between the normal and the x- or y-directions is closer. For 1D hyperbolic nonlinear systems of conservation laws, we use the moving normal shock wave as a test case for the 1D compressible

  9. IDEF method-based simulation model design and development framework

    Directory of Open Access Journals (Sweden)

    Ki-Young Jeong

    2009-09-01

    Full Text Available The purpose of this study is to provide an IDEF method-based integrated framework for a business process simulation model to reduce the model development time by increasing the communication and knowledge reusability during a simulation project. In this framework, simulation requirements are collected by a function modeling method (IDEF0 and a process modeling method (IDEF3. Based on these requirements, a common data model is constructed using the IDEF1X method. From this reusable data model, multiple simulation models are automatically generated using a database-driven simulation model development approach. The framework is claimed to help both requirement collection and experimentation phases during a simulation project by improving system knowledge, model reusability, and maintainability through the systematic use of three descriptive IDEF methods and the features of the relational database technologies. A complex semiconductor fabrication case study was used as a testbed to evaluate and illustrate the concepts and the framework. Two different simulation software products were used to develop and control the semiconductor model from the same knowledge base. The case study empirically showed that this framework could help improve the simulation project processes by using IDEF-based descriptive models and the relational database technology. Authors also concluded that this framework could be easily applied to other analytical model generation by separating the logic from the data.

  10. Constraint methods that accelerate free-energy simulations of biomolecules.

    Science.gov (United States)

    Perez, Alberto; MacCallum, Justin L; Coutsias, Evangelos A; Dill, Ken A

    2015-12-28

    Atomistic molecular dynamics simulations of biomolecules are critical for generating narratives about biological mechanisms. The power of atomistic simulations is that these are physics-based methods that satisfy Boltzmann's law, so they can be used to compute populations, dynamics, and mechanisms. But physical simulations are computationally intensive and do not scale well to the sizes of many important biomolecules. One way to speed up physical simulations is by coarse-graining the potential function. Another way is to harness structural knowledge, often by imposing spring-like restraints. But harnessing external knowledge in physical simulations is problematic because knowledge, data, or hunches have errors, noise, and combinatoric uncertainties. Here, we review recent principled methods for imposing restraints to speed up physics-based molecular simulations that promise to scale to larger biomolecules and motions.

  11. Multi-pass Monte Carlo simulation method in nuclear transmutations.

    Science.gov (United States)

    Mateescu, Liviu; Kadambi, N Prasad; Ravindra, Nuggehalli M

    2016-12-01

    Monte Carlo methods, in their direct brute simulation incarnation, bring realistic results if the involved probabilities, be they geometrical or otherwise, remain constant for the duration of the simulation. However, there are physical setups where the evolution of the simulation represents a modification of the simulated system itself. Chief among such evolving simulated systems are the activation/transmutation setups. That is, the simulation starts with a given set of probabilities, which are determined by the geometry of the system, the components and by the microscopic interaction cross-sections. However, the relative weight of the components of the system changes along with the steps of the simulation. A natural measure would be adjusting probabilities after every step of the simulation. On the other hand, the physical system has typically a number of components of the order of Avogadro's number, usually 1025 or 1026 members. A simulation step changes the characteristics for just a few of these members; a probability will therefore shift by a quantity of 1/1025. Such a change cannot be accounted for within a simulation, because then the simulation should have then a number of at least 1028 steps in order to have some significance. This is not feasible, of course. For our computing devices, a simulation of one million steps is comfortable, but a further order of magnitude becomes too big a stretch for the computing resources. We propose here a method of dealing with the changing probabilities, leading to the increasing of the precision. This method is intended as a fast approximating approach, and also as a simple introduction (for the benefit of students) in the very branched subject of Monte Carlo simulations vis-à-vis nuclear reactors. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. New method of fast simulation for a hadron calorimeter response

    CERN Document Server

    Kulchitskii, Yu A; Tokar, S; Zenis, T

    2003-01-01

    In this work we present the new method of a fast Monte-Carlo simulation of a hadron calorimeter response. It is based on the three-dimensional parameterization of the hadronic shower obtained from the ATLAS TILECAL test beam data and GEANT simulations. A new approach of including the longitudinal fluctuations of hadronic shower is described. The obtained results of the fast simulation are in good agreement with the TILECAL experimental data. (15 refs).

  13. Advanced molecular dynamics simulation methods for kinase drug discovery.

    Science.gov (United States)

    Aci-Sèche, Samia; Ziada, Sonia; Braka, Abdennour; Arora, Rohit; Bonnet, Pascal

    2016-04-01

    Interest in the application of molecular dynamics (MD) simulations has increased in the field of protein kinase (PK) drug discovery. PKs belong to an important drug target class because they are directly involved in a number of diseases, including cancer. MD methods simulate dynamic biological and chemical events at an atomic level. This information can be combined with other in silico and experimental methods to efficiently target selected receptors. In this review, we present common and advanced methods of MD simulations and we focus on the recent applications of MD-based methodologies that provided significant insights into the elucidation of biological mechanisms involving PKs and into the discovery of novel kinase inhibitors.

  14. A Software-Defined Radio Simulation Method using Observer Patterns

    NARCIS (Netherlands)

    Moseley, N.A.; Slump, Cornelis H.

    2005-01-01

    A problem with object-oriented simulation models is that internal model states are hidden and cannot be monitored easily. Object-oriented models are essentially black-box models. This article describes a method to expose the internal states of an object-oriented simulation model. Exposure of the

  15. Human swallowing simulation based on videofluorography images using Hamiltonian MPS method

    Science.gov (United States)

    Kikuchi, Takahiro; Michiwaki, Yukihiro; Kamiya, Tetsu; Toyama, Yoshio; Tamai, Tasuku; Koshizuka, Seiichi

    2015-09-01

    In developed nations, swallowing disorders and aspiration pneumonia have become serious problems. We developed a method to simulate the behavior of the organs involved in swallowing to clarify the mechanisms of swallowing and aspiration. The shape model is based on anatomically realistic geometry, and the motion model utilizes forced displacements based on realistic dynamic images to reflect the mechanisms of human swallowing. The soft tissue organs are modeled as nonlinear elastic material using the Hamiltonian MPS method. This method allows for stable simulation of the complex swallowing movement. A penalty method using metaballs is employed to simulate contact between organ walls and smooth sliding along the walls. We performed four numerical simulations under different analysis conditions to represent four cases of swallowing, including a healthy volunteer and a patient with a swallowing disorder. The simulation results were compared to examine the epiglottic downfolding mechanism, which strongly influences the risk of aspiration.

  16. Improving Bariatric Patient Transport and Care with Simulation

    Directory of Open Access Journals (Sweden)

    Brad D. Gable

    2014-03-01

    Full Text Available Introduction: Obesity is prevalent in the United States. Obese patients have physiologic differences from non-obese individuals. Not only does transport and maintenance of these patients require use of specialized equipment, but it also requires a distinct skill set and knowledge base. To date, there is no literature investigating simulation as a model for educating pre-hospital providers in the care of bariatric patients. The purpose of this study was to determine if a 3-hour educational course with simulation could improve paramedics’ knowledge and confidence of bariatric procedures and transport. This study also examined if prior experience with bariatric transport affected training outcomes. Methods: Our study took place in August 2012 during paramedic training sessions. Paramedics completed a pre- and post-test that assessed confidence and knowledge and provided information on previous experience. They had a 30-minute didactic and participated in 2 20-minute hands-on skills portions that reviewed procedural issues in bariatric patients, including airway procedures, peripheral venous and intraosseous access, and cardiopulmonary resuscitation. Study participants took part in one of two simulated patient encounters. Paramedics were challenged with treating emergent traumatic and/or medical conditions, as well as extricating and transporting bariatric patients. Each group underwent a debriefing of the scenario immediately following their case. We measured confidence using a 5-point Likert-type response scale ranging from 1 (strongly disagree to 5 (strongly agree on a 7-item questionnaire. We assessed knowledge with 12 multiple choice questions. Paired-sample t-tests were used to compare pre- and post-simulation confidence and knowledge with a significance level of p≤0.05. We used analysis of covariance to examine the effect of previous experiences on pre-and post-educational activity confidence and knowledge with a significance level of p

  17. A particle-based method for granular flow simulation

    KAUST Repository

    Chang, Yuanzhang

    2012-03-16

    We present a new particle-based method for granular flow simulation. In the method, a new elastic stress term, which is derived from a modified form of the Hooke\\'s law, is included in the momentum governing equation to handle the friction of granular materials. Viscosity force is also added to simulate the dynamic friction for the purpose of smoothing the velocity field and further maintaining the simulation stability. Benefiting from the Lagrangian nature of the SPH method, large flow deformation can be well handled easily and naturally. In addition, a signed distance field is also employed to enforce the solid boundary condition. The experimental results show that the proposed method is effective and efficient for handling the flow of granular materials, and different kinds of granular behaviors can be well simulated by adjusting just one parameter. © 2012 Science China Press and Springer-Verlag Berlin Heidelberg.

  18. Forest canopy BRDF simulation using Monte Carlo method

    NARCIS (Netherlands)

    Huang, J.; Wu, B.; Zeng, Y.; Tian, Y.

    2006-01-01

    Monte Carlo method is a random statistic method, which has been widely used to simulate the Bidirectional Reflectance Distribution Function (BRDF) of vegetation canopy in the field of visible remote sensing. The random process between photons and forest canopy was designed using Monte Carlo method.

  19. Simulation Genres and Student Uptake: The Patient Health Record in Clinical Nursing Simulations

    Science.gov (United States)

    Campbell, Lilly

    2017-01-01

    Drawing on fieldwork, this article examines nursing students' design and use of a patient health record during clinical simulations, where small teams of students provide nursing care for a robotic patient. The student-designed patient health record provides a compelling example of how simulation genres can both authentically coordinate action…

  20. Two Dimensional Lattice Boltzmann Method for Cavity Flow Simulation

    OpenAIRE

    Panjit MUSIK; Krisanadej JAROENSUTASINEE

    2004-01-01

    This paper presents a simulation of incompressible viscous flow within a two-dimensional square cavity. The objective is to develop a method originated from Lattice Gas (cellular) Automata (LGA), which utilises discrete lattice as well as discrete time and can be parallelised easily. Lattice Boltzmann Method (LBM), known as discrete Lattice kinetics which provide an alternative for solving the Navier–Stokes equations and are generally used for fluid simulation, is chosen for the study. A spec...

  1. Motion simulation of hydraulic driven safety rod using FSI method

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Jaeho; Kim, Sanghaun; Yoo, Yeonsik; Cho, Yeonggarp; Kim, Jong In [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-05-15

    Hydraulic driven safety rod which is one of them is being developed by Division for Reactor Mechanical Engineering, KAERI. In this paper the motion of this rod is simulated by fluid structure interaction (FSI) method before manufacturing for design verification and pump sizing. A newly designed hydraulic driven safety rod which is one of reactivity control mechanism is simulated using FSI method for design verification and pump sizing. The simulation is done in CFD domain with UDF. The pressure drop is changed slightly by flow rates. It means that the pressure drop is mainly determined by weight of moving part. The simulated velocity of piston is linearly proportional to flow rates so the pump can be sized easily according to the rising and drop time requirement of the safety rod using the simulation results.

  2. An introduction to computer simulation methods applications to physical systems

    CERN Document Server

    Gould, Harvey; Christian, Wolfgang

    2007-01-01

    Now in its third edition, this book teaches physical concepts using computer simulations. The text incorporates object-oriented programming techniques and encourages readers to develop good programming habits in the context of doing physics. Designed for readers at all levels , An Introduction to Computer Simulation Methods uses Java, currently the most popular programming language. Introduction, Tools for Doing Simulations, Simulating Particle Motion, Oscillatory Systems, Few-Body Problems: The Motion of the Planets, The Chaotic Motion of Dynamical Systems, Random Processes, The Dynamics of Many Particle Systems, Normal Modes and Waves, Electrodynamics, Numerical and Monte Carlo Methods, Percolation, Fractals and Kinetic Growth Models, Complex Systems, Monte Carlo Simulations of Thermal Systems, Quantum Systems, Visualization and Rigid Body Dynamics, Seeing in Special and General Relativity, Epilogue: The Unity of Physics For all readers interested in developing programming habits in the context of doing phy...

  3. A simulation based engineering method to support HAZOP studies

    DEFF Research Database (Denmark)

    Enemark-Rasmussen, Rasmus; Cameron, David; Angelo, Per Bagge

    2012-01-01

    HAZOP is the most commonly used process hazard analysis tool in industry, a systematic yet tedious and time consuming method. The aim of this study is to explore the feasibility of process dynamic simulations to facilitate the HAZOP studies. We propose a simulation-based methodology to complement...... the conventional HAZOP procedure. The method systematically generates failure scenarios by considering process equipment deviations with pre-defined failure modes. The effect of failure scenarios is then evaluated using dynamic simulations -in this study the K-Spice® software used. The consequences of each failure...... model as case study....

  4. A tool for simulating parallel branch-and-bound methods

    Directory of Open Access Journals (Sweden)

    Golubeva Yana

    2016-01-01

    Full Text Available The Branch-and-Bound method is known as one of the most powerful but very resource consuming global optimization methods. Parallel and distributed computing can efficiently cope with this issue. The major difficulty in parallel B&B method is the need for dynamic load redistribution. Therefore design and study of load balancing algorithms is a separate and very important research topic. This paper presents a tool for simulating parallel Branchand-Bound method. The simulator allows one to run load balancing algorithms with various numbers of processors, sizes of the search tree, the characteristics of the supercomputer’s interconnect thereby fostering deep study of load distribution strategies. The process of resolution of the optimization problem by B&B method is replaced by a stochastic branching process. Data exchanges are modeled using the concept of logical time. The user friendly graphical interface to the simulator provides efficient visualization and convenient performance analysis.

  5. Comparing Intravenous Insertion Instructional Methods with Haptic Simulators

    Directory of Open Access Journals (Sweden)

    Lenora A. McWilliams

    2017-01-01

    Full Text Available Objective. The objective of this review was to compare traditional intravenous (IV insertion instructional methods with the use of haptic IV simulators. Design. An integrative research design was used to analyze the current literature. Data Sources. A search was conducted using key words intravenous (IV insertion or cannulation or venipuncture and simulation from 2000 to 2015 in the English language. The databases included Academic Search Complete, CINAHL Complete, Education Resource Information Center, and Medline. Review Methods. Whittemore and Knafl’s (2005 strategies were used to critique the articles for themes and similarities. Results. Comparisons of outcomes between traditional IV instructional methods and the use of haptic IV simulators continue to show various results. Positive results indicate that the use of the haptic IV simulator decreases both band constriction and total procedure time. While students are satisfied with practicing on the haptic simulators, they still desire faculty involvement. Conclusion. Combining the haptic IV simulator with practical experience on the IV arm may be the best practice for learning IV insertion. Research employing active learning strategies while using a haptic IV simulator during the learning process may reduce cost and faculty time.

  6. Comparison of EBSD patterns simulated by two multislice methods.

    Science.gov (United States)

    Liu, Q B; Cai, C Y; Zhou, G W; Wang, Y G

    2016-10-01

    The extraction of crystallography information from electron backscatter diffraction (EBSD) patterns can be facilitated by diffraction simulations based on the dynamical electron diffraction theory. In this work, the EBSD patterns are successfully simulated by two multislice methods, that is, the real space (RS) method and the revised real space (RRS) method. The calculation results by the two multislice methods are compared and analyzed in detail with respect to different accelerating voltages, Debye-Waller factors and aperture radii. It is found that the RRS method provides a larger view field of the EBSD patterns than that by the RS method under the same calculation conditions. Moreover, the Kikuchi bands of the EBSD patterns obtained by the RRS method have a better match with the experimental patterns than those by the RS method. Especially, the lattice parameters obtained by the RRS method are more accurate than those by the RS method. These results demonstrate that the RRS method is more accurate for simulating the EBSD patterns than the RS method within the accepted computation time. © 2016 The Authors Journal of Microscopy © 2016 Royal Microscopical Society.

  7. Multilevel panel method for wind turbine rotor flow simulations

    NARCIS (Netherlands)

    van Garrel, Arne

    2016-01-01

    Simulation methods of wind turbine aerodynamics currently in use mainly fall into two categories: the first is the group of traditional low-fidelity engineering models and the second is the group of computationally expensive CFD methods based on the Navier-Stokes equations. For an engineering

  8. The afforestation problem: a heuristic method based on simulated annealing

    DEFF Research Database (Denmark)

    Vidal, Rene Victor Valqui

    1992-01-01

    This paper presents the afforestation problem, that is the location and design of new forest compartments to be planted in a given area. This optimization problem is solved by a two-step heuristic method based on simulated annealing. Tests and experiences with this method are also presented....

  9. Nonequilibrium relaxation method – An alternative simulation strategy

    Indian Academy of Sciences (India)

    Abstract. One well-established simulation strategy to study the thermal phases and transitions of a given microscopic model system is the so-called equilibrium method, in which one first realizes the equilibrium ensemble of a finite system and then extrapolates the results to infinite system. This equilibrium method traces ...

  10. A simple method for potential flow simulation of cascades

    Indian Academy of Sciences (India)

    Department of Mechanical Engineering, Indian Institute of Science,. Bangalore 560 012 e-mail: raghu@mecheng.iisc.ernet.in. MS received 21 April 2009; revised 1 February 2010; accepted 23 August 2010. Abstract. A simple method using a combination of conformal mapping and vortex panel method to simulate potential ...

  11. Steel Fibre Reinforced Concrete Simulation with the SPH Method

    Science.gov (United States)

    Hušek, Martin; Kala, Jiří; Král, Petr; Hokeš, Filip

    2017-10-01

    Steel fibre reinforced concrete (SFRC) is very popular in many branches of civil engineering. Thanks to its increased ductility, it is able to resist various types of loading. When designing a structure, the mechanical behaviour of SFRC can be described by currently available material models (with equivalent material for example) and therefore no problems arise with numerical simulations. But in many scenarios, e.g. high speed loading, it would be a mistake to use such an equivalent material. Physical modelling of the steel fibres used in concrete is usually problematic, though. It is necessary to consider the fact that mesh-based methods are very unsuitable for high-speed simulations with regard to the issues that occur due to the effect of excessive mesh deformation. So-called meshfree methods are much more suitable for this purpose. The Smoothed Particle Hydrodynamics (SPH) method is currently the best choice, thanks to its advantages. However, a numerical defect known as tensile instability may appear when the SPH method is used. It causes the development of numerical (false) cracks, making simulations of ductile types of failure significantly more difficult to perform. The contribution therefore deals with the description of a procedure for avoiding this defect and successfully simulating the behaviour of SFRC with the SPH method. The essence of the problem lies in the choice of coordinates and the description of the integration domain derived from them – spatial (Eulerian kernel) or material coordinates (Lagrangian kernel). The contribution describes the behaviour of both formulations. Conclusions are drawn from the fundamental tasks, and the contribution additionally demonstrates the functionality of SFRC simulations. The random generation of steel fibres and their inclusion in simulations are also discussed. The functionality of the method is supported by the results of pressure test simulations which compare various levels of fibre reinforcement of SFRC

  12. A nondissipative simulation method for the drift kinetic equation

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, Tomo-Hiko; Sugama, Hideo; Sato, Tetsuya

    2001-07-01

    With the aim to study the ion temperature gradient (ITG) driven turbulence, a nondissipative kinetic simulation scheme is developed and comprehensively benchmarked. The new simulation method preserving the time-reversibility of basic kinetic equations can successfully reproduce the analytical solutions of asymmetric three-mode ITG equations which are extended to provide a more general reference for benchmarking than the previous work [T.-H. Watanabe, H. Sugama, and T. Sato: Phys. Plasmas 7 (2000) 984]. It is also applied to a dissipative three-mode system, and shows a good agreement with the analytical solution. The nondissipative simulation result of the ITG turbulence accurately satisfies the entropy balance equation. Usefulness of the nondissipative method for the drift kinetic simulations is confirmed in comparisons with other dissipative schemes. (author)

  13. Airway skills training using a human patient simulator

    African Journals Online (AJOL)

    Thesegan Moodley

    2016-04-11

    Apr 11, 2016 ... Patient simulators are widely employed in educational models ... Sarasota, USA) into our education model. ... Each teaching. Airway skills training using a human patient simulator. Thesegan Moodley* and Dean Gopalan. Discipline of Anaesthesiology and Critical Care, Nelson R Mandela School of ...

  14. Standardised patient-simulated practice learning: A rich ...

    African Journals Online (AJOL)

    Background. Nursing education needs to adapt to be relevant to student nurses' learning needs. This study investigates the use of standardised patients (SPs) in a simulated patient interview as a learning strategy to bridge the theory-practice gap. Simulation helps students to develop skills such as communication, higher ...

  15. Adaptive implicit method for thermal compositional reservoir simulation

    Energy Technology Data Exchange (ETDEWEB)

    Agarwal, A.; Tchelepi, H.A. [Society of Petroleum Engineers, Richardson, TX (United States)]|[Stanford Univ., Palo Alto (United States)

    2008-10-15

    As the global demand for oil increases, thermal enhanced oil recovery techniques are becoming increasingly important. Numerical reservoir simulation of thermal methods such as steam assisted gravity drainage (SAGD) is complex and requires a solution of nonlinear mass and energy conservation equations on a fine reservoir grid. The most currently used technique for solving these equations is the fully IMplicit (FIM) method which is unconditionally stable, allowing for large timesteps in simulation. However, it is computationally expensive. On the other hand, the method known as IMplicit pressure explicit saturations, temperature and compositions (IMPEST) is computationally inexpensive, but it is only conditionally stable and restricts the timestep size. To improve the balance between the timestep size and computational cost, the thermal adaptive IMplicit (TAIM) method uses stability criteria and a switching algorithm, where some simulation variables such as pressure, saturations, temperature, compositions are treated implicitly while others are treated with explicit schemes. This presentation described ongoing research on TAIM with particular reference to thermal displacement processes such as the stability criteria that dictate the maximum allowed timestep size for simulation based on the von Neumann linear stability analysis method; the switching algorithm that adapts labeling of reservoir variables as implicit or explicit as a function of space and time; and, complex physical behaviors such as heat and fluid convection, thermal conduction and compressibility. Key numerical results obtained by enhancing Stanford's General Purpose Research Simulator (GPRS) were also presented along with a list of research challenges. 14 refs., 2 tabs., 11 figs., 1 appendix.

  16. Comparing three patient-controlled analgesia methods.

    Science.gov (United States)

    Hoare, K; Sousa, K H; Person, L; De Ryke, P; Piper, J

    2000-02-01

    Among 301 patients randomly assigned to use one of three methods for patient-controlled analgesia (PCA), no statistically significant differences were found for self-reported pain or acceptability of PCA method. Methods yielded differences in on-demand bolus analgesia use and number of symptoms.

  17. Geostatistic in Reservoir Characterization: from estimation to simulation methods

    OpenAIRE

    Mata Lima, H.

    2005-01-01

    In this article objective have been made to reviews different geostatistical methods available to estimate and simulate petrophysical properties (porosity and permeability) of the reservoir. Different geostatistical techniques that allow the combination of hard and soft data are taken into account and one refers the main reason to use the geostatistical simulation rather than estimation. Uncertainty in reservoir characterization due to variogram assumption, which is a strict mathematical equa...

  18. Pharmacy students' preferences for various types of simulated patients.

    Science.gov (United States)

    Gallimore, Casey; George, Angela K; Brown, Michael C

    2008-02-15

    To evaluate pharmacy students' preferences for various types of simulated patients. Second-professional year (P2) pharmacy students participated in 7 learning activities that used simulated patients including community volunteers, College administrative staff, course instructors, and student peers. Students ranked each simulated patient type according to believability, skill development, and preference using a 5-point Likert scale. One-hundred seven of 155 students (69%) completed the survey instrument. Students preferred community volunteers as simulated patients (mean rank 1.39), followed by peers (2.22), instructors (2.63), and staff members (2.81) (p volunteers receiving the highest ratings (p volunteers over staff members and their peers. Future scholarship should explore the relationship among simulated patient types and student learning outcomes.

  19. A virtual source method for Monte Carlo simulation of Gamma Knife Model C

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Tae Hoon; Kim, Yong Kyun [Hanyang University, Seoul (Korea, Republic of); Chung, Hyun Tai [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    2016-05-15

    The Monte Carlo simulation method has been used for dosimetry of radiation treatment. Monte Carlo simulation is the method that determines paths and dosimetry of particles using random number. Recently, owing to the ability of fast processing of the computers, it is possible to treat a patient more precisely. However, it is necessary to increase the simulation time to improve the efficiency of accuracy uncertainty. When generating the particles from the cobalt source in a simulation, there are many particles cut off. So it takes time to simulate more accurately. For the efficiency, we generated the virtual source that has the phase space distribution which acquired a single gamma knife channel. We performed the simulation using the virtual sources on the 201 channel and compared the measurement with the simulation using virtual sources and real sources. A virtual source file was generated to reduce the simulation time of a Gamma Knife Model C. Simulations with a virtual source executed about 50 times faster than the original source code and there was no statistically significant difference in simulated results.

  20. Diagnostic method for induction motor using simplified motor simulator

    OpenAIRE

    Doumae, Yukihiro; Konishi, Masami; Imai, Jun; Asada, Hideki; Kitamura, Akira

    2001-01-01

    In this paper, an identification method of motor parameters for the diagnosis of rotor bar defects in the squirrel cage induction motor is proposed. It is difficult to distinguish the degree of deterioration by a conventional diagnostic method such as Fourier analysis. To overcome the difficulty, a motor simulator is used to identify the degree of deterioration of rotors in the squirrel cage induction motor. Using this method, the deterioration of rotor bars in the motor can be estimated quan...

  1. Validation of Solution Methods for Building Energy Simulation

    OpenAIRE

    Crowley, Michael

    2006-01-01

    The most commonly applied mathematical solution techniques for building energy simulation are response function methods and finite difference methods. The accepted validation methodology in this domain has as its main elements empirical validation, analytical verification and inter-model comparison. Of these, only analytical verification tests the solution method exclusively; but the test examples used are too confined to be representative of the building energy problem. A discriminating and ...

  2. Simulating Hair with the Loosely-Connected Particles Method

    OpenAIRE

    Soták, Šimon

    2010-01-01

    This thesis presents an implementation of the Loosely Connected Particles (LCP) method of hair animation proposed by Bando et al. We updated the method with several modern approaches. Firstly, we implemented two variations of parallel processing for the simulation which di er in work distribution among threads. The results indicate that work is distributed evenly, and thus dynamic distribution is not needed. Secondly, we applied the Deep Opacity Maps method of hair shadowing on the LCP and in...

  3. Innovative teaching methods in the professional training of nurses – simulation education

    Directory of Open Access Journals (Sweden)

    Michaela Miertová

    2013-12-01

    Full Text Available Introduction: The article is aimed to highlight usage of innovative teaching methods within simulation education in the professional training of nurses abroad and to present our experience based on passing intensive study programme at School of Nursing, Midwifery and Social Work, University of Salford (United Kingdom, UK within Intensive EU Lifelong Learning Programme (LPP Erasmus EU RADAR 2013. Methods: Implementation of simulation methods such as role-play, case studies, simulation scenarios, practical workshops and clinical skills workstation within structured ABCDE approach (AIM© Assessment and Management Tool was aimed to promote the development of theoretical knowledge and skills to recognize and manage acutely deteriorated patients. Structured SBAR approach (Acute SBAR Communication Tool was used for the training of communication and information sharing among the members of multidisciplinary health care team. OSCE approach (Objective Structured Clinical Examination was used for student’s individual formative assessment. Results: Simulation education is proved to have lots of benefits in the professional training of nurses. It is held in safe, controlled and realistic conditions (in simulation laboratories reflecting real hospital and community care environment with no risk of harming real patients accompanied by debriefing, discussion and analysis of all activities students have performed within simulated scenario. Such learning environment is supportive, challenging, constructive, motivated, engaging, skilled, flexible, inspiring and respectful. Thus the simulation education is effective, interactive, interesting, efficient and modern way of nursing education. Conclusion: Critical thinking and clinical competences of nurses are crucial for early recognition and appropriate response to acute deterioration of patient’s condition. These competences are important to ensure the provision of high quality nursing care. Methods of

  4. Simulation of dry granular flows using discrete element methods

    Science.gov (United States)

    Martin, Hugo; Lefebvre, Aline; Maday, Yvon; Mangeney, Anne; Maury, Bertrand; Sainte-Marie, Jacques

    2017-04-01

    Granular flows are composed of interacting particles (for instance sand grains). While natural flow simulations at the field scale are generally based on continuum models, discrete element methods are very useful to get insight into the detailed contact interactions between the particles involved. We shall consider here both well known molecular dynamics (MD) and contact dynamics (CD) methods to simulate granular particle interaction. The difference between these methods is the linearisation of contact forces in MD. We are interested to compare these methods, and especially the effects of the linearisation in simulations. In the present work, we introduce a new rigid bodies model at the scale of the particles and its resolution by contact dynamics. The interesting aspect of our CD method is to treat the contacts in all the material system in one step without any iterative process required when the contacts are dealt with one after the other. All contacts are calculated here at the same time in just one iteration and the normal and tangential constraints are treated simultaneously. The present model follows from a convex optimization problem presented in [1] by B. Maury in which we add a frictional behaviour to the contact law between the particles. To analyse the behaviour of this model, we compare our results to analytical solutions when we can compute them and otherwise to simulations with molecular dynamics method. [1] A time-stepping scheme for inelastic collisions. Numerical handling of the nonoverlapping constraint, B. Maury, Numerische Mathematik, 17 january 2006.

  5. A General Simulation Method for Multiple Bodies in Proximate Flight

    Science.gov (United States)

    Meakin, Robert L.

    2003-01-01

    Methods of unsteady aerodynamic simulation for an arbitrary number of independent bodies flying in close proximity are considered. A novel method to efficiently detect collision contact points is described. A method to compute body trajectories in response to aerodynamic loads, applied loads, and inter-body collisions is also given. The physical correctness of the methods are verified by comparison to a set of analytic solutions. The methods, combined with a Navier-Stokes solver, are used to demonstrate the possibility of predicting the unsteady aerodynamics and flight trajectories of moving bodies that involve rigid-body collisions.

  6. Using Simulation to Train Junior Psychiatry Residents to Work with Agitated Patients: A Pilot Study

    Science.gov (United States)

    Zigman, Daniel; Young, Meredith; Chalk, Colin

    2013-01-01

    Objective: This article examines the benefit and feasibility of introducing a new, simulation-based learning intervention for junior psychiatry residents. Method: Junior psychiatry residents were invited to participate in a new simulation-based learning intervention focusing on agitated patients. Questionnaires were used to explore the success of…

  7. MONTE CARLO METHOD AND APPLICATION IN @RISK SIMULATION SYSTEM

    Directory of Open Access Journals (Sweden)

    Gabriela Ižaríková

    2015-12-01

    Full Text Available The article is an example of using the software simulation @Risk designed for simulation in Microsoft Excel spread sheet, demonstrated the possibility of its usage in order to show a universal method of solving problems. The simulation is experimenting with computer models based on the real production process in order to optimize the production processes or the system. The simulation model allows performing a number of experiments, analysing them, evaluating, optimizing and afterwards applying the results to the real system. A simulation model in general is presenting modelling system by using mathematical formulations and logical relations. In the model is possible to distinguish controlled inputs (for instance investment costs and random outputs (for instance demand, which are by using a model transformed into outputs (for instance mean value of profit. In case of a simulation experiment at the beginning are chosen controlled inputs and random (stochastic outputs are generated randomly. Simulations belong into quantitative tools, which can be used as a support for a decision making.

  8. Computational methods for coupling microstructural and micromechanical materials response simulations

    Energy Technology Data Exchange (ETDEWEB)

    HOLM,ELIZABETH A.; BATTAILE,CORBETT C.; BUCHHEIT,THOMAS E.; FANG,HUEI ELIOT; RINTOUL,MARK DANIEL; VEDULA,VENKATA R.; GLASS,S. JILL; KNOROVSKY,GERALD A.; NEILSEN,MICHAEL K.; WELLMAN,GERALD W.; SULSKY,DEBORAH; SHEN,YU-LIN; SCHREYER,H. BUCK

    2000-04-01

    Computational materials simulations have traditionally focused on individual phenomena: grain growth, crack propagation, plastic flow, etc. However, real materials behavior results from a complex interplay between phenomena. In this project, the authors explored methods for coupling mesoscale simulations of microstructural evolution and micromechanical response. In one case, massively parallel (MP) simulations for grain evolution and microcracking in alumina stronglink materials were dynamically coupled. In the other, codes for domain coarsening and plastic deformation in CuSi braze alloys were iteratively linked. this program provided the first comparison of two promising ways to integrate mesoscale computer codes. Coupled microstructural/micromechanical codes were applied to experimentally observed microstructures for the first time. In addition to the coupled codes, this project developed a suite of new computational capabilities (PARGRAIN, GLAD, OOF, MPM, polycrystal plasticity, front tracking). The problem of plasticity length scale in continuum calculations was recognized and a solution strategy was developed. The simulations were experimentally validated on stockpile materials.

  9. Simulation methods with extended stability for stiff biochemical Kinetics

    Directory of Open Access Journals (Sweden)

    Rué Pau

    2010-08-01

    Full Text Available Abstract Background With increasing computer power, simulating the dynamics of complex systems in chemistry and biology is becoming increasingly routine. The modelling of individual reactions in (biochemical systems involves a large number of random events that can be simulated by the stochastic simulation algorithm (SSA. The key quantity is the step size, or waiting time, τ, whose value inversely depends on the size of the propensities of the different channel reactions and which needs to be re-evaluated after every firing event. Such a discrete event simulation may be extremely expensive, in particular for stiff systems where τ can be very short due to the fast kinetics of some of the channel reactions. Several alternative methods have been put forward to increase the integration step size. The so-called τ-leap approach takes a larger step size by allowing all the reactions to fire, from a Poisson or Binomial distribution, within that step. Although the expected value for the different species in the reactive system is maintained with respect to more precise methods, the variance at steady state can suffer from large errors as τ grows. Results In this paper we extend Poisson τ-leap methods to a general class of Runge-Kutta (RK τ-leap methods. We show that with the proper selection of the coefficients, the variance of the extended τ-leap can be well-behaved, leading to significantly larger step sizes. Conclusions The benefit of adapting the extended method to the use of RK frameworks is clear in terms of speed of calculation, as the number of evaluations of the Poisson distribution is still one set per time step, as in the original τ-leap method. The approach paves the way to explore new multiscale methods to simulate (biochemical systems.

  10. High viscosity fluid simulation using particle-based method

    KAUST Repository

    Chang, Yuanzhang

    2011-03-01

    We present a new particle-based method for high viscosity fluid simulation. In the method, a new elastic stress term, which is derived from a modified form of the Hooke\\'s law, is included in the traditional Navier-Stokes equation to simulate the movements of the high viscosity fluids. Benefiting from the Lagrangian nature of Smoothed Particle Hydrodynamics method, large flow deformation can be well handled easily and naturally. In addition, in order to eliminate the particle deficiency problem near the boundary, ghost particles are employed to enforce the solid boundary condition. Compared with Finite Element Methods with complicated and time-consuming remeshing operations, our method is much more straightforward to implement. Moreover, our method doesn\\'t need to store and compare to an initial rest state. The experimental results show that the proposed method is effective and efficient to handle the movements of highly viscous flows, and a large variety of different kinds of fluid behaviors can be well simulated by adjusting just one parameter. © 2011 IEEE.

  11. Event by event method for quantum interference simulation

    NARCIS (Netherlands)

    Mutia Delina, M

    2014-01-01

    Event by event method is a simulation approach which is not based on the knowledge of the Schrödinger equation. This approach uses the classical wave theory and particle concept: we use particles, not waves. The data is obtained by counting the events that were detected by the detector, just as in

  12. A multiscale quantum mechanics/electromagnetics method for device simulations.

    Science.gov (United States)

    Yam, ChiYung; Meng, Lingyi; Zhang, Yu; Chen, GuanHua

    2015-04-07

    Multiscale modeling has become a popular tool for research applying to different areas including materials science, microelectronics, biology, chemistry, etc. In this tutorial review, we describe a newly developed multiscale computational method, incorporating quantum mechanics into electronic device modeling with the electromagnetic environment included through classical electrodynamics. In the quantum mechanics/electromagnetics (QM/EM) method, the regions of the system where active electron scattering processes take place are treated quantum mechanically, while the surroundings are described by Maxwell's equations and a semiclassical drift-diffusion model. The QM model and the EM model are solved, respectively, in different regions of the system in a self-consistent manner. Potential distributions and current densities at the interface between QM and EM regions are employed as the boundary conditions for the quantum mechanical and electromagnetic simulations, respectively. The method is illustrated in the simulation of several realistic systems. In the case of junctionless field-effect transistors, transfer characteristics are obtained and a good agreement between experiments and simulations is achieved. Optical properties of a tandem photovoltaic cell are studied and the simulations demonstrate that multiple QM regions are coupled through the classical EM model. Finally, the study of a carbon nanotube-based molecular device shows the accuracy and efficiency of the QM/EM method.

  13. Development of new deactivation method for simulation of fluid ...

    Indian Academy of Sciences (India)

    Selection of a good catalyst is the easiest way to increase profitability of a fluid catalytic cracking (FCC) unit. During operation, these ... New rapid deactivation method has been developed to simulate plant equilibrium catalyst (E-Cat) by modifying metal impregnation, steaming and oxidation/reduction procedures. The E-Cat ...

  14. Space-time multiscale methods for Large Eddy Simulation

    NARCIS (Netherlands)

    Munts, E.A.

    2006-01-01

    The Variational Multiscale (VMS) method has appeared as a promising new approach to the Large Eddy Simulation (LES) of turbulent flows. The key advantage of the VMS approach is that it allows different subgrid-scale (SGS) modeling assumptions to be made at different ranges of the resolved scales.

  15. Practical considerations for incomplete factorization methods in reservoir simulation

    Energy Technology Data Exchange (ETDEWEB)

    Behie, A.; Forsyth, P.A.

    1983-11-01

    Various incomplete factorization (ILU) methods coupled with ORTHOMIN acceleration are discussed. These include natural, D2 and D4 orderings with several degrees of factorization, the modified factorization (MILU) and the COMBINATIVE method. These techniques can also be used with the bordered systems resulting from fully-coupled, fully-implicit multi-block wells. Test results are reported for fully implicit black oil and fully implicit thermal simulations. Some results are also reported for vector and scalar modes on the CRAY.

  16. A method of outdoor simulation of infrared radiance of targets

    Science.gov (United States)

    Song, Jiang-tao; Shen, Xiang-heng; Zhao, Ying-jie

    2009-07-01

    Current research on infrared simulation often focuses mainly on infrared imaging simulation by computer and pays little attention to outdoor simulation of infrared radiation characteristics of targets. In order to simulate infrared radiance of targets outdoors, in this paper we propose a new outdoor simulation method on the basis of heating the cloth by electricity. There are two major contributions in the paper. Firstly, uneven distributing of temperature field of the cloth surface is considered and the long-wave thermal imager is used as a link of the temperature control system. On the basis of many experiments, the expression is concluded about the relation of the temperature obtained by the lone-wave thermal imager and the temperature obtained by the temperature control system and the environmental temperature at the experimental scene. Secondly, the influence of the environment at the experimental scene on the infrared radiance of the cloth surface is thought over. Thanks to two measures above, simulation precision of infrared radiance is made much better. The results of many outdoor experiments demonstrate the performance of the proposed approach.

  17. Who's Driving? The role and training of the human patient simulation operator.

    Science.gov (United States)

    Gantt, Laura

    2012-11-01

    Within the airline industry, where much of simulation-based education originated, cockpit simulators are operated by current or former pilots whose expertise ensures the authenticity of the training experience. As yet, identifying the most appropriate person to run a patient simulator has not been translated into healthcare. Furthermore, few training resources exist for those who must learn the intricacies of the relationship between patient simulators, simulation scenarios, and educational objectives. This article reviews literature related to the role, educational preparation, and training of the patient simulator operator and explores solutions to the uncertainty about the difference between simulator operators and technicians. Because simulators are operationally intensive and because scarce faculty may be best used to facilitate student learning within the laboratory, the tendency has been to use a variety of personnel to manage patient simulators. Recommendations for standardizing the role of the operator that are consistent with the pedagogical purposes of simulation are offered. Potential questions are posed, and methods for future work are discussed.

  18. System and Method for Finite Element Simulation of Helicopter Turbulence

    Science.gov (United States)

    McFarland, R. E. (Inventor); Dulsenberg, Ken (Inventor)

    1999-01-01

    The present invention provides a turbulence model that has been developed for blade-element helicopter simulation. This model uses an innovative temporal and geometrical distribution algorithm that preserves the statistical characteristics of the turbulence spectra over the rotor disc, while providing velocity components in real time to each of five blade-element stations along each of four blades. for a total of twenty blade-element stations. The simulator system includes a software implementation of flight dynamics that adheres to the guidelines for turbulence set forth in military specifications. One of the features of the present simulator system is that it applies simulated turbulence to the rotor blades of the helicopter, rather than to its center of gravity. The simulator system accurately models the rotor penetration into a gust field. It includes time correlation between the front and rear of the main rotor, as well as between the side forces felt at the center of gravity and at the tail rotor. It also includes features for added realism, such as patchy turbulence and vertical gusts in to which the rotor disc penetrates. These features are realized by a unique real time implementation of the turbulence filters. The new simulator system uses two arrays one on either side of the main rotor to record the turbulence field and to produce time-correlation from the front to the rear of the rotor disc. The use of Gaussian Interpolation between the two arrays maintains the statistical properties of the turbulence across the rotor disc. The present simulator system and method may be used in future and existing real-time helicopter simulations with minimal increase in computational workload.

  19. Feasibility of patient specific aortic blood flow CFD simulation.

    Science.gov (United States)

    Svensson, Johan; Gårdhagen, Roland; Heiberg, Einar; Ebbers, Tino; Loyd, Dan; Länne, Toste; Karlsson, Matts

    2006-01-01

    Patient specific modelling of the blood flow through the human aorta is performed using computational fluid dynamics (CFD) and magnetic resonance imaging (MRI). Velocity patterns are compared between computer simulations and measurements. The workflow includes several steps: MRI measurement to obtain both geometry and velocity, an automatic levelset segmentation followed by meshing of the geometrical model and CFD setup to perform the simulations follwed by the actual simulations. The computational results agree well with the measured data.

  20. IC space radiation effects experimental simulation and estimation methods

    CERN Document Server

    Chumakov, A I; Telets, V A; Gerasimov, V F; Yanenko, A V; Sogoyan, A V

    1999-01-01

    Laboratory test simulation methods are developed for IC response prediction to space radiation. The minimum set of radiation simulators is proposed to investigate IC failures and upsets under space radiation. The accelerated test technique of MOS ICs degradation estimation are developed for low intensity irradiation taking into account temperature variations as well as latent degradation effects. Two-parameter cross section functions are adapted to describe the ion- and proton-induced single event upsets. Non-focused laser irradiation is found to be applicable for single event latchup threshold estimation.

  1. Meshfree simulation of avalanches with the Finite Pointset Method (FPM)

    Science.gov (United States)

    Michel, Isabel; Kuhnert, Jörg; Kolymbas, Dimitrios

    2017-04-01

    Meshfree methods are the numerical method of choice in case of applications which are characterized by strong deformations in conjunction with free surfaces or phase boundaries. In the past the meshfree Finite Pointset Method (FPM) developed by Fraunhofer ITWM (Kaiserslautern, Germany) has been successfully applied to problems in computational fluid dynamics such as water crossing of cars, water turbines, and hydraulic valves. Most recently the simulation of granular flows, e.g. soil interaction with cars (rollover), has also been tackled. This advancement is the basis for the simulation of avalanches. Due to the generalized finite difference formulation in FPM, the implementation of different material models is quite simple. We will demonstrate 3D simulations of avalanches based on the Drucker-Prager yield criterion as well as the nonlinear barodesy model. The barodesy model (Division of Geotechnical and Tunnel Engineering, University of Innsbruck, Austria) describes the mechanical behavior of soil by an evolution equation for the stress tensor. The key feature of successful and realistic simulations of avalanches - apart from the numerical approximation of the occurring differential operators - is the choice of the boundary conditions (slip, no-slip, friction) between the different phases of the flow as well as the geometry. We will discuss their influences for simplified one- and two-phase flow examples. This research is funded by the German Research Foundation (DFG) and the FWF Austrian Science Fund.

  2. Numerical Simulation of Solitary Waves Using Smoothed Particle Hydrodynamics Method

    Directory of Open Access Journals (Sweden)

    Swapnadip De Chowdhury

    2012-09-01

    Full Text Available Understanding shallow water wave propagation is of major concern in any coastal mitigation effort. Many times, a solitary wave replicates a shallow water wave in its extreme sense which includes a tsunami wave. It is mainly due to known physical characteristics of such waves. Therefore, the study of propagation of solitary waves in the near shore waters is of equal importance in the context of non linear water waves. Owing to the significant growth in computational technologies in the last few decades, a significant number of numerical methods have emerged and applied to simulate nonlinear solitary wave propagation. In this study, one such method, the Smoothed Particle Hydrodynamics (SPH method has been described to simulate the solitary waves. The split-up of a single solitary wave while it crosses a continental kind of shelf has been simulated by the present model. Then SPH model is coupled with the Boussinesq model to predict the time interval between two successive solitary waves on landfall. It has also been shown to be equally efficient in simulating the wave breaking while a solitary wave propagates over a mild slope.

  3. Reduction Method for Real-Time Simulations in Hybrid Testing

    DEFF Research Database (Denmark)

    Andersen, Sebastian; Poulsen, Peter Noe

    2014-01-01

    to reformulate kinematic nonlinear equations of motion into a sum of constant matrices each multiplied by a reduced coordinate decreasing the assembling time. Furthermore the method allows for cutting off some of the higher frequency content not representing real physics decreasing the stability requirement......Real-time hybrid testing combines testing of physical components with numerical simulations. The concept of the method requires that the numerical simulations should be executed in real time. However, for large numerical models including nonlinear behavior a combination of computationally costly...... of choosing a sufficient basis a composite beam and a cantilever beam including kinematic nonlinearities and exposed to harmonic loadings are analyzed. To reduce locking modes with higher order terms are included. From the analysis it is concluded that the method exhibits encouraging potential with respect...

  4. Using Simulated Patients to Teach Clinical Nutrition.

    Science.gov (United States)

    Carroll, J. Gregory; And Others

    1983-01-01

    "Clinical Nutrition in an Interdisciplinary Setting" is a course designed to introduce basic nutrition knowledge and concepts of nutritional assessment, counseling, and intervention in the clinical care of patients. Provides a brief course overview and descriptions of its development, use, and preliminary evaluation of the patient simulation…

  5. Flow-induced noise simulation using detached eddy simulation and the finite element acoustic analogy method

    Directory of Open Access Journals (Sweden)

    Kai Liu

    2016-06-01

    Full Text Available Signals in long-distance pipes are complex due to flow-induced noise generated in special structure, and the computation of these noise sources is difficult and time-consuming. To address this problem, a hybrid method based on computational fluid dynamics and Lighthill’s acoustic analogy theory is proposed to simulate flow-induced noise, with the results showing that the method is sufficient for noise predictions. The proposed method computes the turbulent flow field using detached eddy simulation and then calculates turbulence-generated sound using the finite element acoustic analogy method, which solves acoustic sources as volume sources. The velocity field obtained in the detached eddy simulation computation provides the sound source through interpolation between the computational fluid dynamics and acoustic meshes. The hybrid method is validated and assessed by comparing data from the cavity in pipe and large eddy simulation results. The peak value of flow-induced noise calculated at the monitor point is in good agreement with experimental data available in the literature.

  6. Clinical simulation as an evaluation method in health informatics

    DEFF Research Database (Denmark)

    Jensen, Sanne

    2016-01-01

    Safe work processes and information systems are vital in health care. Methods for design of health IT focusing on patient safety are one of many initiatives trying to prevent adverse events. Possible patient safety hazards need to be investigated before health IT is integrated with local clinical...

  7. [Pollen information of airborne Japanese cedar pollen using a simulation method].

    Science.gov (United States)

    Takahashi, Y; Kawashima, S; Aikawa, S

    1996-04-01

    We have developed a simulation method of airborne Cryptomeria japonica pollen distribution on a map displayed visually on a TV screen. Each patient can be available the information where the place he or she lives. The pollen season in 1995, we served the information about airborne pollen distribution on a map and C. japonica flowering areas on a map to a local resident through TV broadcasting. To verify the simulation method, comparison was made between the result from actual pollen counting and from simulation. It was clarified that both results were comparatively agreed on daily basis. Problem about compatibility among personal computers were solved to rewrite the program of displaying the image using Visual Basic for MS-Windows and create image files. The files can be read continuously by animation software. We think the information can be offered to local resident, local clinicians and patients waiting at the clinics by use of computer networks.

  8. Numerical simulation of explosive welding using Smoothed Particle Hydrodynamics method

    Directory of Open Access Journals (Sweden)

    J Feng

    2017-09-01

    Full Text Available In order to investigate the mechanism of explosive welding and the influences of explosive welding parameters on the welding quality, this paper presents numerical simulation of the explosive welding of Al-Mg plates using Smoothed Particle Hydrodynamics method. The multi-physical phenomena of explosive welding, including acceleration of the flyer plate driven by explosive detonation, oblique collision of the flyer and base plates, jetting phenomenon and the formation of wavy interface can be reproduced in the simulation. The characteristics of explosive welding are analyzed based on the simulation results. The mechanism of wavy interface formation is mainly due to oscillation of the collision point on the bonding surfaces. In addition, the impact velocity and collision angle increase with the increase of the welding parameters, such as explosive thickness and standoff distance, resulting in enlargement of the interfacial waves.

  9. Recent advancements in medical simulation: patient-specific virtual reality simulation.

    Science.gov (United States)

    Willaert, Willem I M; Aggarwal, Rajesh; Van Herzeele, Isabelle; Cheshire, Nicholas J; Vermassen, Frank E

    2012-07-01

    Patient-specific virtual reality simulation (PSVR) is a new technological advancement that allows practice of upcoming real operations and complements the established role of VR simulation as a generic training tool. This review describes current developments in PSVR and draws parallels with other high-stake industries, such as aviation, military, and sports. A review of the literature was performed using PubMed and Internet search engines to retrieve data relevant to PSVR in medicine. All reports pertaining to PSVR were included. Reports on simulators that did not incorporate a haptic interface device were excluded from the review. Fifteen reports described 12 simulators that enabled PSVR. Medical procedures in the field of laparoscopy, vascular surgery, orthopedics, neurosurgery, and plastic surgery were included. In all cases, source data was two-dimensional CT or MRI data. Face validity was most commonly reported. Only one (vascular) simulator had undergone face, content, and construct validity. Of the 12 simulators, 1 is commercialized and 11 are prototypes. Five simulators have been used in conjunction with real patient procedures. PSVR is a promising technological advance within medicine. The majority of simulators are still in the prototype phase. As further developments unfold, the validity of PSVR will have to be examined much like generic VR simulation for training purposes. Nonetheless, similar to the aviation, military, and sport industries, operative performance and patient safety may be enhanced by the application of this novel technology.

  10. Unstructured spectral element methods of simulation of turbulent flows

    Energy Technology Data Exchange (ETDEWEB)

    Henderson, R.D. [California Inst. of Technology, Pasadena, CA (United States); Karniadakis, G.E. [Brown Univ., Providence, RI (United States)

    1995-12-01

    In this paper we present a spectral element-Fourier algorithm for simulating incompressible turbulent flows in complex geometries using unstructured quadrilateral meshes. To this end, we compare two different interface formulations for extending the conforming spectral element method in order to allow for surgical mesh refinement and still retain spectral accuracy: the Zanolli iterative procedure and variational patching based on auxiliary {open_quotes}mortar{close_quotes} functions. We present an interpretation of the original mortar element method as a patching scheme and develop direct and iterative solution techniques that make the method efficient for simulations of turbulent flows. The properties of the new method are analyzed in detail by studying the eigenspectra of the advection and diffusion operators. We then present numerical results that illustrate the flexibility as well as the exponential convergence of the new algorithm for nonconforming discretizations. We conclude with simulation studies of the turbulent cylinder wake at Re = 1000 (external flow) and turbulent flow over riblets at Re = 3280 (internal flow). 36 refs., 29 figs., 7 tabs.

  11. Assessing numerical methods for molecular and particle simulation.

    Science.gov (United States)

    Shang, Xiaocheng; Kröger, Martin; Leimkuhler, Benedict

    2017-11-22

    We discuss the design of state-of-the-art numerical methods for molecular dynamics, focusing on the demands of soft matter simulation, where the purposes include sampling and dynamics calculations both in and out of equilibrium. We discuss the characteristics of different algorithms, including their essential conservation properties, the convergence of averages, and the accuracy of numerical discretizations. Formulations of the equations of motion which are suited to both equilibrium and nonequilibrium simulation include Langevin dynamics, dissipative particle dynamics (DPD), and the more recently proposed "pairwise adaptive Langevin" (PAdL) method, which, like DPD but unlike Langevin dynamics, conserves momentum and better matches the relaxation rate of orientational degrees of freedom. PAdL is easy to code and suitable for a variety of problems in nonequilibrium soft matter modeling; our simulations of polymer melts indicate that this method can also provide dramatic improvements in computational efficiency. Moreover we show that PAdL gives excellent control of the relaxation rate to equilibrium. In the nonequilibrium setting, we further demonstrate that while PAdL allows the recovery of accurate shear viscosities at higher shear rates than are possible using the DPD method at identical timestep, it also outperforms Langevin dynamics in terms of stability and accuracy at higher shear rates.

  12. Cultural Competence Clinic: An Online, Interactive, Simulation for Working Effectively with Arab American Muslim Patients

    Science.gov (United States)

    Smith, Brian Daniel; Silk, Kami

    2011-01-01

    Objective: This pilot study investigates the impact of an online, interactive simulation involving an Arab American Muslim patient on the knowledge, skills, and attitudes of 2nd-year medical students regarding culturally competent healthcare, both in general and specific to Arab American Muslim patients. Method: Participants (N = 199), were…

  13. Modified network simulation model with token method of bus access

    Directory of Open Access Journals (Sweden)

    L.V. Stribulevich

    2013-08-01

    Full Text Available Purpose. To study the characteristics of the local network with the marker method of access to the bus its modified simulation model was developed. Methodology. Defining characteristics of the network is carried out on the developed simulation model, which is based on the state diagram-layer network station with the mechanism of processing priorities, both in steady state and in the performance of control procedures: the initiation of a logical ring, the entrance and exit of the station network with a logical ring. Findings. A simulation model, on the basis of which can be obtained the dependencies of the application the maximum waiting time in the queue for different classes of access, and the reaction time usable bandwidth on the data rate, the number of network stations, the generation rate applications, the number of frames transmitted per token holding time, frame length was developed. Originality. The technique of network simulation reflecting its work in the steady condition and during the control procedures, the mechanism of priority ranking and handling was proposed. Practical value. Defining network characteristics in the real-time systems on railway transport based on the developed simulation model.

  14. SIMULATION OF PULSED BREAKDOWN IN HELIUM BY ADAPTIVE METHODS

    Directory of Open Access Journals (Sweden)

    S. I. Eliseev

    2014-09-01

    Full Text Available The paper deals with the processes occurring during electrical breakdown in gases as well as numerical simulation of these processes using adaptive mesh refinement methods. Discharge between needle electrodes in helium at atmospheric pressure is selected for the test simulation. Physical model of the accompanying breakdown processes is based on self- consistent system of continuity equations for streams of charged particles (electrons and positive ions and Poisson equation for electric potential. Sharp plasma heterogeneity in the area of streamers requires the usage of adaptive algorithms for constructing of computational grids for modeling. The method for grid adaptive construction together with justification of its effectiveness for significantly unsteady gas breakdown simulation at atmospheric pressure is described. Upgraded version of Gerris package is used for numerical simulation of electrical gas breakdown. Software package, originally focused on solution of nonlinear problems in fluid dynamics, appears to be suitable for processes modeling in non-stationary plasma described by continuity equations. The usage of adaptive grids makes it possible to get an adequate numerical model for the breakdown development in the system of needle electrodes. Breakdown dynamics is illustrated by contour plots of electron densities and electric field intensity obtained in the course of solving. Breakdown mechanism of positive and negative (orientated to anode streamers formation is demonstrated and analyzed. Correspondence between adaptive building of computational grid and generated plasma gradients is shown. Obtained results can be used as a basis for full-scale numerical experiments on electric breakdown in gases.

  15. Discrete Particle Method for Simulating Hypervelocity Impact Phenomena

    Directory of Open Access Journals (Sweden)

    Erkai Watson

    2017-04-01

    Full Text Available In this paper, we introduce a computational model for the simulation of hypervelocity impact (HVI phenomena which is based on the Discrete Element Method (DEM. Our paper constitutes the first application of DEM to the modeling and simulating of impact events for velocities beyond 5 kms-1. We present here the results of a systematic numerical study on HVI of solids. For modeling the solids, we use discrete spherical particles that interact with each other via potentials. In our numerical investigations we are particularly interested in the dynamics of material fragmentation upon impact. We model a typical HVI experiment configuration where a sphere strikes a thin plate and investigate the properties of the resulting debris cloud. We provide a quantitative computational analysis of the resulting debris cloud caused by impact and a comprehensive parameter study by varying key parameters of our model. We compare our findings from the simulations with recent HVI experiments performed at our institute. Our findings are that the DEM method leads to very stable, energy–conserving simulations of HVI scenarios that map the experimental setup where a sphere strikes a thin plate at hypervelocity speed. Our chosen interaction model works particularly well in the velocity range where the local stresses caused by impact shock waves markedly exceed the ultimate material strength.

  16. Discrete Particle Method for Simulating Hypervelocity Impact Phenomena.

    Science.gov (United States)

    Watson, Erkai; Steinhauser, Martin O

    2017-04-02

    In this paper, we introduce a computational model for the simulation of hypervelocity impact (HVI) phenomena which is based on the Discrete Element Method (DEM). Our paper constitutes the first application of DEM to the modeling and simulating of impact events for velocities beyond 5 kms-1. We present here the results of a systematic numerical study on HVI of solids. For modeling the solids, we use discrete spherical particles that interact with each other via potentials. In our numerical investigations we are particularly interested in the dynamics of material fragmentation upon impact. We model a typical HVI experiment configuration where a sphere strikes a thin plate and investigate the properties of the resulting debris cloud. We provide a quantitative computational analysis of the resulting debris cloud caused by impact and a comprehensive parameter study by varying key parameters of our model. We compare our findings from the simulations with recent HVI experiments performed at our institute. Our findings are that the DEM method leads to very stable, energy-conserving simulations of HVI scenarios that map the experimental setup where a sphere strikes a thin plate at hypervelocity speed. Our chosen interaction model works particularly well in the velocity range where the local stresses caused by impact shock waves markedly exceed the ultimate material strength.

  17. Electromagnetic metamaterial simulations using a GPU-accelerated FDTD method

    Science.gov (United States)

    Seok, Myung-Su; Lee, Min-Gon; Yoo, SeokJae; Park, Q.-Han

    2015-12-01

    Metamaterials composed of artificial subwavelength structures exhibit extraordinary properties that cannot be found in nature. Designing artificial structures having exceptional properties plays a pivotal role in current metamaterial research. We present a new numerical simulation scheme for metamaterial research. The scheme is based on a graphic processing unit (GPU)-accelerated finite-difference time-domain (FDTD) method. The FDTD computation can be significantly accelerated when GPUs are used instead of only central processing units (CPUs). We explain how the fast FDTD simulation of large-scale metamaterials can be achieved through communication optimization in a heterogeneous CPU/GPU-based computer cluster. Our method also includes various advanced FDTD techniques: the non-uniform grid technique, the total-field/scattered-field (TFSF) technique, the auxiliary field technique for dispersive materials, the running discrete Fourier transform, and the complex structure setting. We demonstrate the power of our new FDTD simulation scheme by simulating the negative refraction of light in a coaxial waveguide metamaterial.

  18. A New Parallel Method for Binary Black Hole Simulations

    Directory of Open Access Journals (Sweden)

    Quan Yang

    2016-01-01

    Full Text Available Simulating binary black hole (BBH systems are a computationally intensive problem and it can lead to great scientific discovery. How to explore more parallelism to take advantage of the large number of computing resources of modern supercomputers is the key to achieve high performance for BBH simulations. In this paper, we propose a scalable MPM (Mesh based Parallel Method which can explore both the inter- and intramesh level parallelism to improve the performance of BBH simulation. At the same time, we also leverage GPU to accelerate the performance. Different kinds of performance tests are conducted on Blue Waters. Compared with the existing method, our MPM can improve the performance from 5x speedup (compared with the normalized speed of 32 MPI processes to 8x speedup. For the GPU accelerated version, our MPM can improve the performance from 12x speedup to 28x speedup. Experimental results also show that when only enough CPU computing resource or limited GPU computing resource is available, our MPM can employ two special scheduling mechanisms to achieve better performance. Furthermore, our scalable GPU acceleration MPM can achieve almost ideal weak scaling up to 2048 GPU computing nodes which enables our software to handle even larger BBH simulations efficiently.

  19. Assessing methods for dealing with treatment switching in randomised controlled trials: a simulation study

    Directory of Open Access Journals (Sweden)

    Latimer Nicholas

    2011-01-01

    Full Text Available Abstract Background We investigate methods used to analyse the results of clinical trials with survival outcomes in which some patients switch from their allocated treatment to another trial treatment. These included simple methods which are commonly used in medical literature and may be subject to selection bias if patients switching are not typical of the population as a whole. Methods which attempt to adjust the estimated treatment effect, either through adjustment to the hazard ratio or via accelerated failure time models, were also considered. A simulation study was conducted to assess the performance of each method in a number of different scenarios. Results 16 different scenarios were identified which differed by the proportion of patients switching, underlying prognosis of switchers and the size of true treatment effect. 1000 datasets were simulated for each of these and all methods applied. Selection bias was observed in simple methods when the difference in survival between switchers and non-switchers were large. A number of methods, particularly the AFT method of Branson and Whitehead were found to give less biased estimates of the true treatment effect in these situations. Conclusions Simple methods are often not appropriate to deal with treatment switching. Alternative approaches such as the Branson & Whitehead method to adjust for switching should be considered.

  20. Calibration of three rainfall simulators with automatic measurement methods

    Science.gov (United States)

    Roldan, Margarita

    2010-05-01

    CALIBRATION OF THREE RAINFALL SIMULATORS WITH AUTOMATIC MEASUREMENT METHODS M. Roldán (1), I. Martín (2), F. Martín (2), S. de Alba(3), M. Alcázar(3), F.I. Cermeño(3) 1 Grupo de Investigación Ecología y Gestión Forestal Sostenible. ECOGESFOR-Universidad Politécnica de Madrid. E.U.I.T. Forestal. Avda. Ramiro de Maeztu s/n. Ciudad Universitaria. 28040 Madrid. margarita.roldan@upm.es 2 E.U.I.T. Forestal. Avda. Ramiro de Maeztu s/n. Ciudad Universitaria. 28040 Madrid. 3 Facultad de Ciencias Geológicas. Universidad Complutense de Madrid. Ciudad Universitaria s/n. 28040 Madrid The rainfall erosivity is the potential ability of rain to cause erosion. It is function of the physical characteristics of rainfall (Hudson, 1971). Most expressions describing erosivity are related to kinetic energy or momentum and so with drop mass or size and fall velocity. Therefore, research on factors determining erosivity leds to the necessity to study the relation between fall height and fall velocity for different drop sizes, generated in a rainfall simulator (Epema G.F.and Riezebos H.Th, 1983) Rainfall simulators are one of the most used tools for erosion studies and are used to determine fall velocity and drop size. Rainfall simulators allow repeated and multiple measurements The main reason for use of rainfall simulation as a research tool is to reproduce in a controlled way the behaviour expected in the natural environment. But in many occasions when simulated rain is used in order to compare it with natural rain, there is a lack of correspondence between natural and simulated rain and this can introduce some doubt about validity of data because the characteristics of natural rain are not adequately represented in rainfall simulation research (Dunkerley D., 2008). Many times the rainfall simulations have high rain rates and they do not resemble natural rain events and these measures are not comparables. And besides the intensity is related to the kinetic energy which

  1. A simulation study of three methods for detecting disease clusters

    Directory of Open Access Journals (Sweden)

    Samuelsen Sven O

    2006-04-01

    Full Text Available Abstract Background Cluster detection is an important part of spatial epidemiology because it can help identifying environmental factors associated with disease and thus guide investigation of the aetiology of diseases. In this article we study three methods suitable for detecting local spatial clusters: (1 a spatial scan statistic (SaTScan, (2 generalized additive models (GAM and (3 Bayesian disease mapping (BYM. We conducted a simulation study to compare the methods. Seven geographic clusters with different shapes were initially chosen as high-risk areas. Different scenarios for the magnitude of the relative risk of these areas as compared to the normal risk areas were considered. For each scenario the performance of the methods were assessed in terms of the sensitivity, specificity, and percentage correctly classified for each cluster. Results The performance depends on the relative risk, but all methods are in general suitable for identifying clusters with a relative risk larger than 1.5. However, it is difficult to detect clusters with lower relative risks. The GAM approach had the highest sensitivity, but relatively low specificity leading to an overestimation of the cluster area. Both the BYM and the SaTScan methods work well. Clusters with irregular shapes are more difficult to detect than more circular clusters. Conclusion Based on our simulations we conclude that the methods differ in their ability to detect spatial clusters. Different aspects should be considered for appropriate choice of method such as size and shape of the assumed spatial clusters and the relative importance of sensitivity and specificity. In general, the BYM method seems preferable for local cluster detection with relatively high relative risks whereas the SaTScan method appears preferable for lower relative risks. The GAM method needs to be tuned (using cross-validation to get satisfactory results.

  2. Transformation-optics simulation method for stimulated Brillouin scattering

    Science.gov (United States)

    Zecca, Roberto; Bowen, Patrick T.; Smith, David R.; Larouche, Stéphane

    2016-12-01

    We develop an approach to enable the full-wave simulation of stimulated Brillouin scattering and related phenomena in a frequency-domain, finite-element environment. The method uses transformation-optics techniques to implement a time-harmonic coordinate transform that reconciles the different frames of reference used by electromagnetic and mechanical finite-element solvers. We show how this strategy can be successfully applied to bulk and guided systems, comparing the results with the predictions of established theory.

  3. Numerical Simulation Method for Combustion in a Oxyhydrogen Rocket Motor

    OpenAIRE

    Taki, Shiro; Fujiwara, Toshitaka; 滝, 史郎; 藤原, 俊隆

    1984-01-01

    Numerical simulations of unsteady phenomena in the combustion chamber of an oxyhydrogen rocket motor were made in an attempt to develop a computer code for use in investigating such phenomena as vibrating combustion. The combustion in this system is controlled by diffusion, the effect of which works much slower than sound or pressure waves, so that diffusions are usually solved using the implicit finite difference method for unlimited time step size caused by stability criterion. However, the...

  4. From fuel cells to batteries: Synergies, scales and simulation methods

    OpenAIRE

    Bessler, Wolfgang G.

    2011-01-01

    The recent years have shown a dynamic growth of battery research and development activities both in academia and industry, supported by large governmental funding initiatives throughout the world. A particular focus is being put on lithium-based battery technologies. This situation provides a stimulating environment for the fuel cell modeling community, as there are considerable synergies in the modeling and simulation methods for fuel cells and batteries. At the same time, batter...

  5. Parallel implementation of the particle simulation method with dynamic load balancing: Toward realistic geodynamical simulation

    Science.gov (United States)

    Furuichi, M.; Nishiura, D.

    2015-12-01

    Fully Lagrangian methods such as Smoothed Particle Hydrodynamics (SPH) and Discrete Element Method (DEM) have been widely used to solve the continuum and particles motions in the computational geodynamics field. These mesh-free methods are suitable for the problems with the complex geometry and boundary. In addition, their Lagrangian nature allows non-diffusive advection useful for tracking history dependent properties (e.g. rheology) of the material. These potential advantages over the mesh-based methods offer effective numerical applications to the geophysical flow and tectonic processes, which are for example, tsunami with free surface and floating body, magma intrusion with fracture of rock, and shear zone pattern generation of granular deformation. In order to investigate such geodynamical problems with the particle based methods, over millions to billion particles are required for the realistic simulation. Parallel computing is therefore important for handling such huge computational cost. An efficient parallel implementation of SPH and DEM methods is however known to be difficult especially for the distributed-memory architecture. Lagrangian methods inherently show workload imbalance problem for parallelization with the fixed domain in space, because particles move around and workloads change during the simulation. Therefore dynamic load balance is key technique to perform the large scale SPH and DEM simulation. In this work, we present the parallel implementation technique of SPH and DEM method utilizing dynamic load balancing algorithms toward the high resolution simulation over large domain using the massively parallel super computer system. Our method utilizes the imbalances of the executed time of each MPI process as the nonlinear term of parallel domain decomposition and minimizes them with the Newton like iteration method. In order to perform flexible domain decomposition in space, the slice-grid algorithm is used. Numerical tests show that our

  6. Mixture and method for simulating soiling and weathering of surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Sleiman, Mohamad; Kirchstetter, Thomas; Destaillats, Hugo; Levinson, Ronnen; Berdahl, Paul; Akbari, Hashem

    2018-01-02

    This disclosure provides systems, methods, and apparatus related to simulated soiling and weathering of materials. In one aspect, a soiling mixture may include an aqueous suspension of various amounts of salt, soot, dust, and humic acid. In another aspect, a method may include weathering a sample of material in a first exposure of the sample to ultraviolet light, water vapor, and elevated temperatures, depositing a soiling mixture on the sample, and weathering the sample in a second exposure of the sample to ultraviolet light, water vapor, and elevated temperatures.

  7. [Numerical flow simulation : A new method for assessing nasal breathing].

    Science.gov (United States)

    Hildebrandt, T; Osman, J; Goubergrits, L

    2016-08-01

    The current options for objective assessment of nasal breathing are limited. The maximum they can determine is the total nasal resistance. Possibilities to analyze the endonasal airstream are lacking. In contrast, numerical flow simulation is able to provide detailed information of the flow field within the nasal cavity. Thus, it has the potential to analyze the nasal airstream of an individual patient in a comprehensive manner and only a computed tomography (CT) scan of the paranasal sinuses is required. The clinical application is still limited due to the necessary technical and personnel resources. In particular, a statistically based referential characterization of normal nasal breathing does not yet exist in order to be able to compare and classify the simulation results.

  8. The Simulation-Tabulation Method for Classical Diffusion Monte Carlo

    Science.gov (United States)

    Hwang, Chi-Ok; Given, James A.; Mascagni, Michael

    2001-12-01

    Many important classes of problems in materials science and biotechnology require the solution of the Laplace or Poisson equation in disordered two-phase domains in which the phase interface is extensive and convoluted. Green's function first-passage (GFFP) methods solve such problems efficiently by generalizing the “walk on spheres” (WOS) method to allow first-passage (FP) domains to be not just spheres but a wide variety of geometrical shapes. (In particular, this solves the difficulty of slow convergence with WOS by allowing FP domains that contain patches of the phase interface.) Previous studies accomplished this by using geometries for which the Green's function was available in quasi-analytic form. Here, we extend these studies by using the simulation-tabulation (ST) method. We simulate and then tabulate surface Green's functions that cannot be obtained analytically. The ST method is applied to the Solc-Stockmayer model with zero potential, to the mean trapping rate of a diffusing particle in a domain of nonoverlapping spherical traps, and to the effective conductivity for perfectly insulating, nonoverlapping spherical inclusions in a matrix of finite conductivity. In all cases, this class of algorithms provides the most efficient methods known to solve these problems to high accuracy.

  9. Multigrid Methods for Fully Implicit Oil Reservoir Simulation

    Science.gov (United States)

    Molenaar, J.

    1996-01-01

    In this paper we consider the simultaneous flow of oil and water in reservoir rock. This displacement process is modeled by two basic equations: the material balance or continuity equations and the equation of motion (Darcy's law). For the numerical solution of this system of nonlinear partial differential equations there are two approaches: the fully implicit or simultaneous solution method and the sequential solution method. In the sequential solution method the system of partial differential equations is manipulated to give an elliptic pressure equation and a hyperbolic (or parabolic) saturation equation. In the IMPES approach the pressure equation is first solved, using values for the saturation from the previous time level. Next the saturations are updated by some explicit time stepping method; this implies that the method is only conditionally stable. For the numerical solution of the linear, elliptic pressure equation multigrid methods have become an accepted technique. On the other hand, the fully implicit method is unconditionally stable, but it has the disadvantage that in every time step a large system of nonlinear algebraic equations has to be solved. The most time-consuming part of any fully implicit reservoir simulator is the solution of this large system of equations. Usually this is done by Newton's method. The resulting systems of linear equations are then either solved by a direct method or by some conjugate gradient type method. In this paper we consider the possibility of applying multigrid methods for the iterative solution of the systems of nonlinear equations. There are two ways of using multigrid for this job: either we use a nonlinear multigrid method or we use a linear multigrid method to deal with the linear systems that arise in Newton's method. So far only a few authors have reported on the use of multigrid methods for fully implicit simulations. Two-level FAS algorithm is presented for the black-oil equations, and linear multigrid for

  10. The Riemann walk: A method for simulating complex actions

    Science.gov (United States)

    Gocksch, Andreas

    1988-05-01

    A new method to simulate systems with complex actions is discussed. It is based on the stochastic evaluation of a certain density of states which explicitly depends on the “imaginary energy” but also has an implicit dependence on the parameters of the real part of the action. Since expectation values are obtained by approximating an integral by a Riemann sum, the method can be considered to be a hybrid between Monte Carlo and Riemann integration. Indeed, for the simple case of a complex coupling the method reduces to what is known as “stratified sampling”. In this letter the method is applied to the SU(3) spin model at finite chemical potential.

  11. Learning style impact on knowledge gains in human patient simulation.

    Science.gov (United States)

    Shinnick, Mary Ann; Woo, Mary A

    2015-01-01

    Human patient simulation (HPS) is a widely used method of teaching in nursing education. While it is believed that a student's learning style impacts knowledge gains in HPS, there is little evidence to support this. This study sought to determine the impact of learning style on knowledge gains after a heart failure (HF) simulation experience in pre-licensure nursing students. A convenience sample of four cohorts of prelicensure nursing students (n=161) were recruited from three Baccalaureate Schools of Nursing at the same point in their curriculum (age 25.7±6.6 years; gender=85.5% female) and participated in HPS using a HF simulation on a high-fidelity manikin. Learning style was assessed by the Kolb Learning Style Inventory (LSI) and pre- and post-HPS knowledge measured by parallel, validated, knowledge tests. The LSI identifies 4 learning styles, (Assimilating Diverging, Accommodating, and Converging). In some cases, learners present a balanced learning profile-an emphasis of all four equally. Statistical analysis consisted of t-tests and ANOVA. HF knowledge scores post-HPS compared to pre-HPS scores revealed a mean improvement of 7 points (plearning. Within group score increases between the pre-test and post-test were seen for the Assimilating (66.68±20.87 to 83.35±12.59; p=0.07), Diverging (61.95±11.08 to 69.86±12.33; plearning styles. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Parallel discrete vortex methods for viscous flow simulation

    Science.gov (United States)

    Takeda, Kenji

    In this thesis a parallel discrete vortex method is developed in order to investigate the long-time behaviour of bluff body wakes. The method is based on inviscid theory, and its extension to include viscous effects is a far from trivial problem. In this work four grid-free viscous models are directly compared to assess their accuracy and efficiency. The random walk, diffusion velocity, corrected core-spreading and vorticity redistribution methods are compared for simulating unbounded fluid flows, and for flows past an impulsively started cylinder at Reynolds numbers between 550 and 9500. The code uses a common core, so that the only free parameters are those directly related to the viscous models. The vorticity redistribution method encompasses all of the advantages of a purely Lagrangian method and incorporates a dynamic regridding scheme to maintain accurate discretisation of the vorticity field. This is used to simulate long-time flow past an impulsively started cylinder for Reynolds numbers 100, 150 and 1000. The code is fully parallel and achieves good speedup on both commodity and proprietary supercomputer systems. At Reynolds numbers below 150 the breakdown of the primary vortex street has been simulated. Results reveal a merging process, causing relaxation to a parallel shear flow. This itself sheds vortices, creating a secondary wake of increased wavelength. At Reynolds number 1000 the cylinder wake becomes chaotic, forming distinct vortex couples. These couples self-convect and can travel upstream. This has a destabilising effect on the vortex street, inducing merging, formation of tripolar and quadrupolar structures and, ultimately, spontaneous ejection of vortex couples upstream of the initial disturbance.

  13. What can virtual patient simulation offer mental health nursing education?

    Science.gov (United States)

    Guise, V; Chambers, M; Välimäki, M

    2012-06-01

    This paper discusses the use of simulation in nursing education and training, including potential benefits and barriers associated with its use. In particular, it addresses the hitherto scant application of diverse simulation devices and dedicated simulation scenarios in psychiatric and mental health nursing. It goes on to describe a low-cost, narrative-based virtual patient simulation technique which has the potential for wide application within health and social care education. An example of the implementation of this technology in a web-based pilot course for acute mental health nurses is given. This particular virtual patient technique is a simulation type ideally suited to promoting essential mental health nursing skills such as critical thinking, communication and decision making. Furthermore, it is argued that it is particularly amenable to e-learning and blended learning environments, as well as being an apt tool where multilingual simulations are required. The continued development, implementation and evaluation of narrative virtual patient simulations across a variety of health and social care programmes would help ascertain their success as an educational tool. © 2011 Blackwell Publishing.

  14. Numerical method for IR background and clutter simulation

    Science.gov (United States)

    Quaranta, Carlo; Daniele, Gina; Balzarotti, Giorgio

    1997-06-01

    The paper describes a fast and accurate algorithm of IR background noise and clutter generation for application in scene simulations. The process is based on the hypothesis that background might be modeled as a statistical process where amplitude of signal obeys to the Gaussian distribution rule and zones of the same scene meet a correlation function with exponential form. The algorithm allows to provide an accurate mathematical approximation of the model and also an excellent fidelity with reality, that appears from a comparison with images from IR sensors. The proposed method shows advantages with respect to methods based on the filtering of white noise in time or frequency domain as it requires a limited number of computation and, furthermore, it is more accurate than the quasi random processes. The background generation starts from a reticule of few points and by means of growing rules the process is extended to the whole scene of required dimension and resolution. The statistical property of the model are properly maintained in the simulation process. The paper gives specific attention to the mathematical aspects of the algorithm and provides a number of simulations and comparisons with real scenes.

  15. A fast mollified impulse method for biomolecular atomistic simulations

    Energy Technology Data Exchange (ETDEWEB)

    Fath, L., E-mail: lukas.fath@kit.edu [Institute for App. and Num. Mathematics, Karlsruhe Institute of Technology (Germany); Hochbruck, M., E-mail: marlis.hochbruck@kit.edu [Institute for App. and Num. Mathematics, Karlsruhe Institute of Technology (Germany); Singh, C.V., E-mail: chandraveer.singh@utoronto.ca [Department of Materials Science & Engineering, University of Toronto (Canada)

    2017-03-15

    Classical integration methods for molecular dynamics are inherently limited due to resonance phenomena occurring at certain time-step sizes. The mollified impulse method can partially avoid this problem by using appropriate filters based on averaging or projection techniques. However, existing filters are computationally expensive and tedious in implementation since they require either analytical Hessians or they need to solve nonlinear systems from constraints. In this work we follow a different approach based on corotation for the construction of a new filter for (flexible) biomolecular simulations. The main advantages of the proposed filter are its excellent stability properties and ease of implementation in standard softwares without Hessians or solving constraint systems. By simulating multiple realistic examples such as peptide, protein, ice equilibrium and ice–ice friction, the new filter is shown to speed up the computations of long-range interactions by approximately 20%. The proposed filtered integrators allow step sizes as large as 10 fs while keeping the energy drift less than 1% on a 50 ps simulation.

  16. Simulation of aortopulmonary collateral flow in Fontan patients for use in prediction of interventional outcomes.

    Science.gov (United States)

    Frieberg, Petter; Sjöberg, Pia; Revstedt, Johan; Heiberg, Einar; Liuba, Petru; Carlsson, Marcus

    2017-08-07

    Patients with complex congenital heart disease may need to be converted to a Fontan circulation with systemic venous return surgically connected to the pulmonary circulation. These patients frequently form aortopulmonary collaterals (APC), that is arterial inflows to the pulmonary artery vascular tree. The aim of this study was to develop a method to calculate the effect of APC on the pulmonary flow distribution based on magnetic resonance imaging (MRI) measurements and computational fluid dynamics simulations in order to enable prediction of interventional outcomes in Fontan patients. Patient-specific models of 11 patients were constructed in a 3D-design software based on MRI segmentations. APC flow was quantified as the difference between pulmonary venous flow and pulmonary artery flow, measured by MRI. A method was developed to include the modulating effect of the APC flow by calculating the patient-specific relative pulmonary vascular resistance. Simulations, including interventions with a Y-graft replacement and a stent dilatation, were validated against MRI results. The bias between simulated and MRI-measured fraction of blood to the left lung was 2·9 ± 5·3%. Including the effects of the APC flow in the simulation (n = 6) reduced simulation error from 9·8 ± 7·0% to 5·2 ± 6·3%. Preliminary findings in two patients show that the effect of surgical and catheter interventions could be predicted using the demonstrated methods. The work demonstrates a novel method to include APC flow in predictive simulations of Fontan hemodynamics. APC flow was found to have a significant contribution to the pulmonary flow distribution in Fontan patients. © 2017 The Authors. Clinical Physiology and Functional Imaging published by John Wiley & Sons Ltd on behalf of Scandinavian Society of Clinical Physiology and Nuclear Medicine.

  17. Multinomial tau-leaping method for stochastic kinetic simulations

    Science.gov (United States)

    Pettigrew, Michel F.; Resat, Haluk

    2007-02-01

    We introduce the multinomial tau-leaping (MτL) method for general reaction networks with multichannel reactant dependencies. The MτL method is an extension of the binomial tau-leaping method where efficiency is improved in several ways. First, τ-leaping steps are determined simply and efficiently using a priori information and Poisson distribution-based estimates of expectation values for reaction numbers over a tentative τ-leaping step. Second, networks are partitioned into closed groups of reactions and corresponding reactants in which no group reactant set is found in any other group. Third, product formation is factored into upper-bound estimation of the number of times a particular reaction occurs. Together, these features allow larger time steps where the numbers of reactions occurring simultaneously in a multichannel manner are estimated accurately using a multinomial distribution. Furthermore, we develop a simple procedure that places a specific upper bound on the total reaction number to ensure non-negativity of species populations over a single multiple-reaction step. Using two disparate test case problems involving cellular processes—epidermal growth factor receptor signaling and a lactose operon model—we show that the τ-leaping based methods such as the MτL algorithm can significantly reduce the number of simulation steps thus increasing the numerical efficiency over the exact stochastic simulation algorithm by orders of magnitude.

  18. Approximate Bayesian computation methods for daily spatiotemporal precipitation occurrence simulation

    Science.gov (United States)

    Olson, Branden; Kleiber, William

    2017-04-01

    Stochastic precipitation generators (SPGs) produce synthetic precipitation data and are frequently used to generate inputs for physical models throughout many scientific disciplines. Especially for large data sets, statistical parameter estimation is difficult due to the high dimensionality of the likelihood function. We propose techniques to estimate SPG parameters for spatiotemporal precipitation occurrence based on an emerging set of methods called Approximate Bayesian computation (ABC), which bypass the evaluation of a likelihood function. Our statistical model employs a thresholded Gaussian process that reduces to a probit regression at single sites. We identify appropriate ABC penalization metrics for our model parameters to produce simulations whose statistical characteristics closely resemble those of the observations. Spell length metrics are appropriate for single sites, while a variogram-based metric is proposed for spatial simulations. We present numerical case studies at sites in Colorado and Iowa where the estimated statistical model adequately reproduces local and domain statistics.

  19. Hardware-in-the-loop grid simulator system and method

    Science.gov (United States)

    Fox, John Curtiss; Collins, Edward Randolph; Rigas, Nikolaos

    2017-05-16

    A hardware-in-the-loop (HIL) electrical grid simulation system and method that combines a reactive divider with a variable frequency converter to better mimic and control expected and unexpected parameters in an electrical grid. The invention provides grid simulation in a manner to allow improved testing of variable power generators, such as wind turbines, and their operation once interconnected with an electrical grid in multiple countries. The system further comprises an improved variable fault reactance (reactive divider) capable of providing a variable fault reactance power output to control a voltage profile, therein creating an arbitrary recovery voltage. The system further comprises an improved isolation transformer designed to isolate zero-sequence current from either a primary or secondary winding in a transformer or pass the zero-sequence current from a primary to a secondary winding.

  20. Simulating condensation on microstructured surfaces using Lattice Boltzmann Method

    Science.gov (United States)

    Alexeev, Alexander; Vasyliv, Yaroslav

    2017-11-01

    We simulate a single component fluid condensing on 2D structured surfaces with different wettability. To simulate the two phase fluid, we use the athermal Lattice Boltzmann Method (LBM) driven by a pseudopotential force. The pseudopotential force results in a non-ideal equation of state (EOS) which permits liquid-vapor phase change. To account for thermal effects, the athermal LBM is coupled to a finite volume discretization of the temperature evolution equation obtained using a thermal energy rate balance for the specific internal energy. We use the developed model to probe the effect of surface structure and surface wettability on the condensation rate in order to identify microstructure topographies promoting condensation. Financial support is acknowledged from Kimberly-Clark.

  1. Creation and Delphi-method refinement of pediatric disaster triage simulations.

    Science.gov (United States)

    Cicero, Mark X; Brown, Linda; Overly, Frank; Yarzebski, Jorge; Meckler, Garth; Fuchs, Susan; Tomassoni, Anthony; Aghababian, Richard; Chung, Sarita; Garrett, Andrew; Fagbuyi, Daniel; Adelgais, Kathleen; Goldman, Ran; Parker, James; Auerbach, Marc; Riera, Antonio; Cone, David; Baum, Carl R

    2014-01-01

    There is a need for rigorously designed pediatric disaster triage (PDT) training simulations for paramedics. First, we sought to design three multiple patient incidents for EMS provider training simulations. Our second objective was to determine the appropriate interventions and triage level for each victim in each of the simulations and develop evaluation instruments for each simulation. The final objective was to ensure that each simulation and evaluation tool was free of bias toward any specific PDT strategy. We created mixed-methods disaster simulation scenarios with pediatric victims: a school shooting, a school bus crash, and a multiple-victim house fire. Standardized patients, high-fidelity manikins, and low-fidelity manikins were used to portray the victims. Each simulation had similar acuity of injuries and 10 victims. Examples include children with special health-care needs, gunshot wounds, and smoke inhalation. Checklist-based evaluation tools and behaviorally anchored global assessments of function were created for each simulation. Eight physicians and paramedics from areas with differing PDT strategies were recruited as Subject Matter Experts (SMEs) for a modified Delphi iterative critique of the simulations and evaluation tools. The modified Delphi was managed with an online survey tool. The SMEs provided an expected triage category for each patient. The target for modified Delphi consensus was ≥85%. Using Likert scales and free text, the SMEs assessed the validity of the simulations, including instances of bias toward a specific PDT strategy, clarity of learning objectives, and the correlation of the evaluation tools to the learning objectives and scenarios. After two rounds of the modified Delphi, consensus for expected triage level was >85% for 28 of 30 victims, with the remaining two achieving >85% consensus after three Delphi iterations. To achieve consensus, we amended 11 instances of bias toward a specific PDT strategy and corrected 10

  2. Simulation of secondary fault shear displacements - method and application

    Science.gov (United States)

    Fälth, Billy; Hökmark, Harald; Lund, Björn; Mai, P. Martin; Munier, Raymond

    2014-05-01

    We present an earthquake simulation method to calculate dynamically and statically induced shear displacements on faults near a large earthquake. Our results are aimed at improved safety assessment of underground waste storage facilities, e.g. a nuclear waste repository. For our simulations, we use the distinct element code 3DEC. We benchmark 3DEC by running an earthquake simulation and then compare the displacement waveforms at a number of surface receivers with the corresponding results obtained from the COMPSYN code package. The benchmark test shows a good agreement in terms of both phase and amplitude. In our application to a potential earthquake near a storage facility, we use a model with a pre-defined earthquake fault plane (primary fault) surrounded by numerous smaller discontinuities (target fractures) representing faults in which shear movements may be induced by the earthquake. The primary fault and the target fractures are embedded in an elastic medium. Initial stresses are applied and the fault rupture mechanism is simulated through a programmed reduction of the primary fault shear strength, which is initiated at a pre-defined hypocenter. The rupture is propagated at a typical rupture propagation speed and arrested when it reaches the fault plane boundaries. The primary fault residual strength properties are uniform over the fault plane. The method allows for calculation of target fracture shear movements induced by static stress redistribution as well as by dynamic effects. We apply the earthquake simulation method in a model of the Forsmark nuclear waste repository site in Sweden with rock mass properties, in situ stresses and fault geometries according to the description of the site established by the Swedish Nuclear Fuel and Waste Management Co (SKB). The target fracture orientations are based on the Discrete Fracture Network model developed for the site. With parameter values set to provide reasonable upper bound estimates of target fracture

  3. Development of modelling method selection tool for health services management: from problem structuring methods to modelling and simulation methods.

    Science.gov (United States)

    Jun, Gyuchan T; Morris, Zoe; Eldabi, Tillal; Harper, Paul; Naseer, Aisha; Patel, Brijesh; Clarkson, John P

    2011-05-19

    There is an increasing recognition that modelling and simulation can assist in the process of designing health care policies, strategies and operations. However, the current use is limited and answers to questions such as what methods to use and when remain somewhat underdeveloped. The aim of this study is to provide a mechanism for decision makers in health services planning and management to compare a broad range of modelling and simulation methods so that they can better select and use them or better commission relevant modelling and simulation work. This paper proposes a modelling and simulation method comparison and selection tool developed from a comprehensive literature review, the research team's extensive expertise and inputs from potential users. Twenty-eight different methods were identified, characterised by their relevance to different application areas, project life cycle stages, types of output and levels of insight, and four input resources required (time, money, knowledge and data). The characterisation is presented in matrix forms to allow quick comparison and selection. This paper also highlights significant knowledge gaps in the existing literature when assessing the applicability of particular approaches to health services management, where modelling and simulation skills are scarce let alone money and time. A modelling and simulation method comparison and selection tool is developed to assist with the selection of methods appropriate to supporting specific decision making processes. In particular it addresses the issue of which method is most appropriate to which specific health services management problem, what the user might expect to be obtained from the method, and what is required to use the method. In summary, we believe the tool adds value to the scarce existing literature on methods comparison and selection.

  4. Conceptualising patient empowerment: a mixed methods study.

    Science.gov (United States)

    Bravo, Paulina; Edwards, Adrian; Barr, Paul James; Scholl, Isabelle; Elwyn, Glyn; McAllister, Marion

    2015-07-01

    In recent years, interventions and health policy programmes have been established to promote patient empowerment, with a particular focus on patients affected by long-term conditions. However, a clear definition of patient empowerment is lacking, making it difficult to assess effectiveness of interventions designed to promote it. The aim in this study was to develop a conceptual map of patient empowerment, including components of patient empowerment and relationships with other constructs such as health literacy, self-management and shared decision-making. A mixed methods study was conducted comprising (i) a scoping literature review to identify and map the components underpinning published definitions of patient empowerment (ii) qualitative interviews with key stakeholders (patients, patient representatives, health managers and health service researchers) to further develop the conceptual map. Data were analysed using qualitative methods. A combination of thematic and framework analysis was used to integrate and map themes underpinning published definitions of patient empowerment with the views of key UK stakeholders. The scoping literature review identified 67 articles that included a definition of patient empowerment. A range of diverse definitions of patient empowerment was extracted. Thematic analysis identified key underpinning themes, and these themes were used to develop an initial coding framework for analysis of interview data. 19 semi-structured interviews were conducted with key stakeholders. Transcripts were analysed using the initial coding framework, and findings were used to further develop the conceptual map. The resulting conceptual map describes that patient empowerment can be conceived as a state ranging across a spectrum from low to high levels of patient empowerment, with the level of patient empowerment potentially measurable using a set of indicators. Five key components of the conceptual map were identified: underpinning ethos, moderators

  5. Analysis of Simulation Methods for Far-end Crosstalk Cancellation

    Directory of Open Access Journals (Sweden)

    P. Lafata

    2011-04-01

    Full Text Available The information capacity of current digital subscriber lines is limited mainly by a crosstalk in metallic cables. The influence of near-end crosstalk (NEXT can be well cancelled by frequency duplex method, but the elimination of far-end crosstalk (FEXT is not so easy. Therefore FEXT is the dominant source of disturbance in current digital subscriber lines (xDSL. One of the most promising solutions for far-end crosstalk cancellation is Vectored Discrete Multi-tone modulation (VDMT. For the testing of VDMT modulation efficiency it will be necessary to implement advanced methods for modeling of far-end crosstalk to obtain required predictions of the crosstalk behavior in a cable. The actual simple FEXT model is not very accurate and does not provide realistic results. That is why the new method for modeling of far-end crosstalk was developed and is presented in this paper. This advanced model is based on the capacitive and inductive unbalances between pairs in a cable and it also respects the cable’s internal structure. The results of the model are subsequently used for the simulation of VDMT modulation and its impact on the FEXT cancellation. These simulations are based on the estimations of transmission speed of VDSL2 lines with VDMT modulation.

  6. The parallel subdomain-levelset deflation method in reservoir simulation

    Science.gov (United States)

    van der Linden, J. H.; Jönsthövel, T. B.; Lukyanov, A. A.; Vuik, C.

    2016-01-01

    Extreme and isolated eigenvalues are known to be harmful to the convergence of an iterative solver. These eigenvalues can be produced by strong heterogeneity in the underlying physics. We can improve the quality of the spectrum by 'deflating' the harmful eigenvalues. In this work, deflation is applied to linear systems in reservoir simulation. In particular, large, sudden differences in the permeability produce extreme eigenvalues. The number and magnitude of these eigenvalues is linked to the number and magnitude of the permeability jumps. Two deflation methods are discussed. Firstly, we state that harmonic Ritz eigenvector deflation, which computes the deflation vectors from the information produced by the linear solver, is unfeasible in modern reservoir simulation due to high costs and lack of parallelism. Secondly, we test a physics-based subdomain-levelset deflation algorithm that constructs the deflation vectors a priori. Numerical experiments show that both methods can improve the performance of the linear solver. We highlight the fact that subdomain-levelset deflation is particularly suitable for a parallel implementation. For cases with well-defined permeability jumps of a factor 104 or higher, parallel physics-based deflation has potential in commercial applications. In particular, the good scalability of parallel subdomain-levelset deflation combined with the robust parallel preconditioner for deflated system suggests the use of this method as an alternative for AMG.

  7. Application of the quadrupole method for simulation of passive thermography

    Science.gov (United States)

    Winfree, William P.; Zalameda, Joseph N.; Gregory, Elizabeth D.

    2017-05-01

    Passive thermography has been shown to be an effective method for in situ and real time nondestructive evaluation (NDE) to measure damage growth in a composite structure during cyclic loading. The heat generation by subsurface flaw results in a measurable thermal profile at the surface. This paper models the heat generation as a planar subsurface source and calculates the resultant temperature profile at the surface using a three dimensional quadrupole. The results of the model are compared to finite difference simulations of the same planar sources.

  8. Application of the Quadrupole Method for Simulation of Passive Thermography

    Science.gov (United States)

    Winfree, William P.; Zalameda, Joseph N.; Gregory, Elizabeth D.

    2017-01-01

    Passive thermography has been shown to be an effective method for in-situ and real time nondestructive evaluation (NDE) to measure damage growth in a composite structure during cyclic loading. The heat generation by subsurface flaw results in a measurable thermal profile at the surface. This paper models the heat generation as a planar subsurface source and calculates the resultant temperature profile at the surface using a three dimensional quadrupole. The results of the model are compared to finite element simulations of the same planar sources and experimental data acquired during cyclic loading of composite specimens.

  9. Discrete Event Simulation of Patient Admissions to a Neurovascular Unit

    Directory of Open Access Journals (Sweden)

    S. Hahn-Goldberg

    2014-01-01

    Full Text Available Evidence exists that clinical outcomes improve for stroke patients admitted to specialized Stroke Units. The Toronto Western Hospital created a Neurovascular Unit (NVU using beds from general internal medicine, Neurology and Neurosurgery to care for patients with stroke and acute neurovascular conditions. Using patient-level data for NVU-eligible patients, a discrete event simulation was created to study changes in patient flow and length of stay pre- and post-NVU implementation. Varying patient volumes and resources were tested to determine the ideal number of beds under various conditions. In the first year of operation, the NVU admitted 507 patients, over 66% of NVU-eligible patient volumes. With the introduction of the NVU, length of stay decreased by around 8%. Scenario testing showed that the current level of 20 beds is sufficient for accommodating the current demand and would continue to be sufficient with an increase in demand of up to 20%.

  10. The finite cell method for bone simulations: verification and validation.

    Science.gov (United States)

    Ruess, Martin; Tal, David; Trabelsi, Nir; Yosibash, Zohar; Rank, Ernst

    2012-03-01

    Standard methods for predicting bone's mechanical response from quantitative computer tomography (qCT) scans are mainly based on classical h-version finite element methods (FEMs). Due to the low-order polynomial approximation, the need for segmentation and the simplified approach to assign a constant material property to each element in h-FE models, these often compromise the accuracy and efficiency of h-FE solutions. Herein, a non-standard method, the finite cell method (FCM), is proposed for predicting the mechanical response of the human femur. The FCM is free of the above limitations associated with h-FEMs and is orders of magnitude more efficient, allowing its use in the setting of computational steering. This non-standard method applies a fictitious domain approach to simplify the modeling of a complex bone geometry obtained directly from a qCT scan and takes into consideration easily the heterogeneous material distribution of the various bone regions of the femur. The fundamental principles and properties of the FCM are briefly described in relation to bone analysis, providing a theoretical basis for the comparison with the p-FEM as a reference analysis and simulation method of high quality. Both p-FEM and FCM results are validated by comparison with an in vitro experiment on a fresh-frozen femur.

  11. Evaluating the Impact of Classroom Education on the Management of Septic Shock Using Human Patient Simulation.

    Science.gov (United States)

    Lighthall, Geoffrey K; Bahmani, Dona; Gaba, David

    2016-02-01

    Classroom lectures are the mainstay of imparting knowledge in a structured manner and have the additional goals of stimulating critical thinking, lifelong learning, and improvements in patient care. The impact of lectures on patient care is difficult to examine in critical care because of the heterogeneity in patient conditions and personnel as well as confounders such as time pressure, interruptions, fatigue, and nonstandardized observation methods. The critical care environment was recreated in a simulation laboratory using a high-fidelity mannequin simulator, where a mannequin simulator with a standardized script for septic shock was presented to trainees. The reproducibility of this patient and associated conditions allowed the evaluation of "clinical performance" in the management of septic shock. In a previous study, we developed and validated tools for the quantitative analysis of house staff managing septic shock simulations. In the present analysis, we examined whether measures of clinical performance were improved in those cases where a lecture on the management of shock preceded a simulated exercise on the management of septic shock. The administration of the septic shock simulations allowed for performance measurements to be calculated for both medical interns and for subsequent management by a larger resident-led team. The analysis revealed that receiving a lecture on shock before managing a simulated patient with septic shock did not produce scores higher than for those who did not receive the previous lecture. This result was similar for both interns managing the patient and for subsequent management by a resident-led team. We failed to find an immediate impact on clinical performance in simulations of septic shock after a lecture on the management of this syndrome. Lectures are likely not a reliable sole method for improving clinical performance in the management of complex disease processes.

  12. Mannequin or standardized patient: participants' assessment of two training modalities in trauma team simulation

    Directory of Open Access Journals (Sweden)

    Wisborg Torben

    2009-01-01

    Full Text Available Abstract Background Trauma team training using simulation has become an educational compensation for a low number of severe trauma patients in 49 of Norway's 50 trauma hospitals for the last 12 years. The hospitals' own simple mannequins have been employed, to enable training without being dependent on expensive and advanced simulators. We wanted to assess the participants' assessment of using a standardized patient instead of a mannequin. Methods Trauma teams in five hospitals were randomly exposed to a mannequin or a standardized patient in two consecutive simulations for each team. In each hospital two teams were trained, with opposite order of simulation modality. Anonymous, written questionnaires were answered by the participants immediately after each simulation. The teams were interviewed as a focus group after the last simulation, reflecting on the difference between the two simulation modalities. Outcome measures were the participants' assessment of their own perceived educational outcome and comparison of the models, in addition to analysis of the interviews. Results Participants' assessed their educational outcome to be high, and unrelated to the order of appearance of patient model. There were no differences in assessment of realism and feeling of embarrassment. Focus groups revealed that the participants felt that the choice between educational modalities should be determined by the simulated case, with high interaction between team and patient being enhanced by a standardized patient. Conclusion Participants' assessment of the outcome of team training seems independent of the simulation modality when the educational goal is training communication, co-operation and leadership within the team.

  13. Application to radiation damage simulation calculation of Monte Carlo method

    Energy Technology Data Exchange (ETDEWEB)

    Aruga, Takeo [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2001-01-01

    Recent progress in Monte Carlo calculation for radiation damage simulation of structural materials to be used in fast breeder reactors or thermonuclear fusion reactors under energetic neutron or charged particle bombardment is reviewed. Specifically usefulness of employing Monte Carlo methods in molecular dynamics calculations to understand mechanical properties change such as dimensional change, strength, creep, fatigue, corrosion, and crack growth of materials under irradiation on the basis of atomic collision processes is stressed. Structure and spatial distribution of point defects in iron, gold, or cooper as demonstrative examples at several hundreds of ps after the movement of primary knock-on atom (PKA) takes place are calculated as a function of PKA energy. The results are compared with those obtained by the method developed by Norgett, Robinson and Torrens and the usefulness is discussed. (S. Ohno)

  14. Simulation of FEL pulse length calculation with THz streaking method

    Energy Technology Data Exchange (ETDEWEB)

    Gorgisyan, I., E-mail: ishkhan.gorgisyan@psi.ch [Paul Scherrer Institut, 5232 Villigen PSI (Switzerland); École Polytechnique Fédérale de Lausanne, Route Cantonale, 1015 Lausanne (Switzerland); Ischebeck, R.; Prat, E.; Reiche, S. [Paul Scherrer Institut, 5232 Villigen PSI (Switzerland); Rivkin, L. [Paul Scherrer Institut, 5232 Villigen PSI (Switzerland); École Polytechnique Fédérale de Lausanne, Route Cantonale, 1015 Lausanne (Switzerland); Juranić, P., E-mail: ishkhan.gorgisyan@psi.ch [Paul Scherrer Institut, 5232 Villigen PSI (Switzerland)

    2016-04-02

    Simulation of THz streaking of photoelectrons created by X-ray pulses from a free-electron laser and reconstruction of the free-electron laser pulse lengths. Having accurate and comprehensive photon diagnostics for the X-ray pulses delivered by free-electron laser (FEL) facilities is of utmost importance. Along with various parameters of the photon beam (such as photon energy, beam intensity, etc.), the pulse length measurements are particularly useful both for the machine operators to measure the beam parameters and monitor the stability of the machine performance, and for the users carrying out pump–probe experiments at such facilities to better understand their measurement results. One of the most promising pulse length measurement techniques used for photon diagnostics is the THz streak camera which is capable of simultaneously measuring the lengths of the photon pulses and their arrival times with respect to the pump laser. This work presents simulations of a THz streak camera performance. The simulation procedure utilizes FEL pulses with two different photon energies in hard and soft X-ray regions, respectively. It recreates the energy spectra of the photoelectrons produced by the photon pulses and streaks them by a single-cycle THz pulse. Following the pulse-retrieval procedure of the THz streak camera, the lengths were calculated from the streaked spectra. To validate the pulse length calculation procedure, the precision and the accuracy of the method were estimated for streaking configuration corresponding to previously performed experiments. The obtained results show that for the discussed setup the method is capable of measuring FEL pulses with about a femtosecond accuracy and precision.

  15. Does training with human patient simulation translate to improved patient safety and outcome?

    Science.gov (United States)

    Shear, Torin D; Greenberg, Steven B; Tokarczyk, Arthur

    2013-04-01

    In this review, we evaluate several articles in an attempt to qualify the effect of human patient simulation in anaesthesia on patient outcome. The recognition of medical error as a significant cause of patient morbidity and mortality has sparked an increased focus on improving healthcare quality and patient safety. Simulation in anaesthesia is a potential tool to help achieve this goal by allowing anaesthesia providers to learn, practice and perfect their craft without a potential harm to patients. It has gained growing traction in the field and is recently a required element in the American Board of Anesthesiology's Maintenance of Certification in Anesthesia programme. Very few studies have evaluated the effect of simulation on patient outcome. To date, one study has demonstrated improved individual clinical performance in anaesthesia after simulation training. Research suggests that simulation-based team training can reduce patient mortality and improve the quality of care as measured by surgical quality improvement measures. Simulation may improve healthcare systems by serving as a tool to detect latent error and drive process improvement. Despite the adoption of simulation, further study is needed to better qualify its effect on patient safety and outcome.

  16. A new tree code method for simulation of planetesimal dynamics

    Science.gov (United States)

    Richardson, D. C.

    1993-03-01

    A new tree code method for simulation of planetesimal dynamics is presented. A self-similarity argument is used to restrict the problem to a small patch of a ring of planetesimals at 1 AU from the sun. The code incorporates a sliding box model with periodic boundary conditions and surrounding ghost particles. The tree is self-repairing and exploits the flattened nature of Keplerian disks to maximize efficiency. The code uses a fourth-order force polynomial integration algorithm with individual particle time-steps. Collisions and mergers, which play an important role in planetesimal evolution, are treated in a comprehensive manner. In typical runs with a few hundred central particles, the tree code is approximately 2-3 times faster than a recent direct summation method and requires about 1 CPU day on a Sparc IPX workstation to simulate 100 yr of evolution. The average relative force error incurred in such runs is less than 0.2 per cent in magnitude. In general, the CPU time as a function of particle number varies in a way consistent with an O(N log N) algorithm. In order to take advantage of facilities available, the code was written in C in a Unix workstation environment. The unique aspects of the code are discussed in detail and the results of a number of performance tests - including a comparison with previous work - are presented.

  17. Spectral element method implementation on GPU for Lamb wave simulation

    Science.gov (United States)

    Kudela, Pawel; Wandowski, Tomasz; Radzienski, Maciej; Ostachowicz, Wieslaw

    2017-04-01

    Parallel implementation of the time domain spectral element method on GPU (Graphics Processing Unit) is presented. The proposed spectral element method implementation is based on sparse matrix storage of local shape function derivatives calculated at Gauss-Lobatto-Legendre points. The algorithm utilizes two basic operations: multiplication of sparse matrix by vector and element-by-element vectors multiplication. Parallel processing is performed on the degree of freedom level. The assembly of resultant force is done by the aid of a mesh coloring algorithm. The implementation enables considerable computation speedup as well as a simulation of complex structural health monitoring systems based on anomalies of propagating Lamb waves. Hence, the complexity of various models can be tested and compared in order to be as close to reality as possible by using modern computers. A comparative example of a composite laminate modeling by using homogenization of material properties in one layer of 3D brick spectral elements with composite in which each ply is simulated by separate layer of 3D brick spectral elements is described. Consequences of application of each technique are explained. Further analysis is performed for composite laminate with delamination. In each case piezoelectric transducer as well as glue layer between actuator and host structure is modeled.

  18. Five Topics Health Care Simulation Can Address to Improve Patient Safety

    DEFF Research Database (Denmark)

    Sollid, Stephen J M; Dieckman, Peter; Aase, Karina

    2017-01-01

    OBJECTIVES: There is little knowledge about which elements of health care simulation are most effective in improving patient safety. When empirical evidence is lacking, a consensus statement can help define priorities in, for example, education and research. A consensus process was therefore...... initiated to define priorities in health care simulation that contribute the most to improve patient safety.  METHODS: An international group of experts took part in a 4-stage consensus process based on a modified nominal group technique. Stages 1 to 3 were based on electronic communication; stage 4 was a 2......-day consensus meeting at the Utstein Abbey in Norway. The goals of stage 4 were to agree on the top 5 topics in health care simulation that contribute the most to patient safety, identify the patient safety problems they relate to, and suggest solutions with implementation strategies...

  19. Fast integral methods for integrated optical systems simulations: a review

    Science.gov (United States)

    Kleemann, Bernd H.

    2015-09-01

    Boundary integral equation methods (BIM) or simply integral methods (IM) in the context of optical design and simulation are rigorous electromagnetic methods solving Helmholtz or Maxwell equations on the boundary (surface or interface of the structures between two materials) for scattering or/and diffraction purposes. This work is mainly restricted to integral methods for diffracting structures such as gratings, kinoforms, diffractive optical elements (DOEs), micro Fresnel lenses, computer generated holograms (CGHs), holographic or digital phase holograms, periodic lithographic structures, and the like. In most cases all of the mentioned structures have dimensions of thousands of wavelengths in diameter. Therefore, the basic methods necessary for the numerical treatment are locally applied electromagnetic grating diffraction algorithms. Interestingly, integral methods belong to the first electromagnetic methods investigated for grating diffraction. The development started in the mid 1960ies for gratings with infinite conductivity and it was mainly due to the good convergence of the integral methods especially for TM polarization. The first integral equation methods (IEM) for finite conductivity were the methods by D. Maystre at Fresnel Institute in Marseille: in 1972/74 for dielectric, and metallic gratings, and later for multiprofile, and other types of gratings and for photonic crystals. Other methods such as differential and modal methods suffered from unstable behaviour and slow convergence compared to BIMs for metallic gratings in TM polarization from the beginning to the mid 1990ies. The first BIM for gratings using a parametrization of the profile was developed at Karl-Weierstrass Institute in Berlin under a contract with Carl Zeiss Jena works in 1984-1986 by A. Pomp, J. Creutziger, and the author. Due to the parametrization, this method was able to deal with any kind of surface grating from the beginning: whether profiles with edges, overhanging non

  20. Bluff Body Flow Simulation Using a Vortex Element Method

    Energy Technology Data Exchange (ETDEWEB)

    Anthony Leonard; Phillippe Chatelain; Michael Rebel

    2004-09-30

    Heavy ground vehicles, especially those involved in long-haul freight transportation, consume a significant part of our nation's energy supply. it is therefore of utmost importance to improve their efficiency, both to reduce emissions and to decrease reliance on imported oil. At highway speeds, more than half of the power consumed by a typical semi truck goes into overcoming aerodynamic drag, a fraction which increases with speed and crosswind. Thanks to better tools and increased awareness, recent years have seen substantial aerodynamic improvements by the truck industry, such as tractor/trailer height matching, radiator area reduction, and swept fairings. However, there remains substantial room for improvement as understanding of turbulent fluid dynamics grows. The group's research effort focused on vortex particle methods, a novel approach for computational fluid dynamics (CFD). Where common CFD methods solve or model the Navier-Stokes equations on a grid which stretches from the truck surface outward, vortex particle methods solve the vorticity equation on a Lagrangian basis of smooth particles and do not require a grid. They worked to advance the state of the art in vortex particle methods, improving their ability to handle the complicated, high Reynolds number flow around heavy vehicles. Specific challenges that they have addressed include finding strategies to accurate capture vorticity generation and resultant forces at the truck wall, handling the aerodynamics of spinning bodies such as tires, application of the method to the GTS model, computation time reduction through improved integration methods, a closest point transform for particle method in complex geometrics, and work on large eddy simulation (LES) turbulence modeling.

  1. Virtual patient simulation at US and Canadian medical schools.

    Science.gov (United States)

    Huang, Grace; Reynolds, Robby; Candler, Chris

    2007-05-01

    "Virtual patients" are computer-based simulations designed to complement clinical training. These applications possess numerous educational benefits but are costly to develop. Few medical schools can afford to create them. The purpose of this inventory was to gather information regarding in-house virtual patient development at U.S. and Canadian medical schools to promote the sharing of existing cases and future collaboration. From February to September 2005, the authors contacted 142 U.S. and Canadian medical schools and requested that they report on virtual patient simulation activities at their respective institutions. The inventory elicited information regarding the pedagogic and technical characteristics of each virtual patient application. The schools were also asked to report on their willingness to share virtual patients. Twenty-six out of 108 responding schools reported that they were producing virtual patients. Twelve schools provided additional data on 103 cases and 111 virtual patients. The vast majority of virtual patients were media rich and were associated with significant production costs and time. The reported virtual patient cases tended to focus on primary care disciplines and did not as a whole exhibit racial or ethnic diversity. Funding sources, production costs, and production duration influenced the extent of schools' willingness to share. Broader access to and cooperative development of these resources would allow medical schools to enhance their clinical curricula. Virtual patient development should include basic science objectives for more integrative learning, simulate the consequences of clinical decision making, and include additional cases in cultural competency. Together, these efforts can enhance medical education despite external constraints on clinical training.

  2. Debriefing after Human Patient Simulation and Nursing Students' Learning

    Science.gov (United States)

    Benhuri, Gloria

    2014-01-01

    Human Patient Simulation (HPS) exercises with life-like computerized manikins provide clinical experiences for nursing students in a safe environment followed by debriefing that promotes learning. Quantitative research in techniques to support learning from debriefing is limited. The purpose of the quantitative quasi-experimental study using a…

  3. High accuracy mantle convection simulation through modern numerical methods

    KAUST Repository

    Kronbichler, Martin

    2012-08-21

    Numerical simulation of the processes in the Earth\\'s mantle is a key piece in understanding its dynamics, composition, history and interaction with the lithosphere and the Earth\\'s core. However, doing so presents many practical difficulties related to the numerical methods that can accurately represent these processes at relevant scales. This paper presents an overview of the state of the art in algorithms for high-Rayleigh number flows such as those in the Earth\\'s mantle, and discusses their implementation in the Open Source code Aspect (Advanced Solver for Problems in Earth\\'s ConvecTion). Specifically, we show how an interconnected set of methods for adaptive mesh refinement (AMR), higher order spatial and temporal discretizations, advection stabilization and efficient linear solvers can provide high accuracy at a numerical cost unachievable with traditional methods, and how these methods can be designed in a way so that they scale to large numbers of processors on compute clusters. Aspect relies on the numerical software packages deal.II and Trilinos, enabling us to focus on high level code and keeping our implementation compact. We present results from validation tests using widely used benchmarks for our code, as well as scaling results from parallel runs. © 2012 The Authors Geophysical Journal International © 2012 RAS.

  4. Hybrid-model for computed tomography simulations and post-patient collimator design

    Science.gov (United States)

    Xu, Horace; Tao, Kun; GK, Padmashree; Wu, Mingye; Cao, Ximiao; Long, Yong; Yan, Ming; Yao, Yangyang; De Man, Bruno

    2014-03-01

    Ray-tracing based simulation methods are widely used in modeling X-ray propagation, detection and imaging. While most of the existing simulation methods rely on analytical modeling, a novel hybrid approach comprising of statistical modeling and analytical approaches, is proposed here. Our hybrid simulator is a unique combination of analytical modeling for evoking the fundamentals of X-ray transport through ray-tracing, and a look-up-table (LUT) based approach for integrating it with the Monte Carlo simulations that model optical photon-transport within scintillator. The LUT approach for scintillation-based X-ray detection invokes depth-dependent gain factors to account for intra-pixel absorption and light-transport, together with incident-angle dependent effects for inter-pixel X-ray absorption (parallax effect). The model simulates the post-patient collimator for scatter-rejection, as an X-ray shadow on scintillator, while handling its position with respect to the pixel boundary, by a smart over-sampling strategy for high efficiency. We have validated this simulator for computed tomography system-simulations, by using real data from GE Brivo CT385. The level of accuracy of image noise and spatial resolution is better than 98%. We have used the simulator for designing the post-patient collimator, and measured modulation transfer function (MTF) for different widths of the collimator plate. Validation and simulation study clearly demonstrates that the hybrid simulator is an accurate, reliable, efficient tool for realistic system-level simulations. It could be deployed for research, design and development purposes to model any scintillator-based X-ray imaging-system (2-dimensional and 3-dimensional), while being equally applicable for medical and industrial imaging.

  5. A java based simulator with user interface to simulate ventilated patients

    Directory of Open Access Journals (Sweden)

    Stehle P.

    2015-09-01

    Full Text Available Mechanical ventilation is a life-saving intervention, which despite its use on a routine basis, poses the risk of inflicting further damage to the lung tissue if ventilator settings are chosen inappropriately. Medical decision support systems may help to prevent such injuries while providing the optimal settings to reach a defined clinical goal. In order to develop and verify decision support algorithms, a test bench simulating a patient’s behaviour is needed. We propose a Java based system that allows simulation of respiratory mechanics, gas exchange and cardiovascular dynamics of a mechanically ventilated patient. The implemented models are allowed to interact and are interchangeable enabling the simulation of various clinical scenarios. Model simulations are running in real-time and show physiologically plausible results.

  6. Evaluating the practice of Iranian community pharmacists regarding oral contraceptive pills using simulated patients.

    Directory of Open Access Journals (Sweden)

    Foroutan N

    2016-12-01

    Full Text Available Background: As oral contraceptive pills are available over the counter in pharmacies, pharmacists are professionally responsible for checking and informing patients about every aspect of taking these drugs. Simulated patient method is a new and robust way to evaluate professional performance of pharmacists. Objective: The aim of the present study was to evaluate the pharmacy practice of Iranian pharmacists regarding over-the-counter use of oral contraceptive pills using simulated patient method. Methods: Simulated patients visited pharmacy with a prescription containing ciprofloxacin and asked for oral contraceptive pills. The pharmacist was expected to ask important questions for using these drugs and to inform the patient about them properly. Moreover, the Pharmacists should advise patients in regard to the possible interaction. Results: Ninety four pharmacists participated in this study. In 24 (25.3% visits, the liable pharmacist was not present at the time of purchase. Furthermore, In 13 (18.57 % visits by the simulated patients, the liable pharmacists did not pay any attention to the simulated patients even when they asked for consultation. Twenty nine (41.43% pharmacists did not ask any question during dispensing. Nausea was the most frequent described side effect by pharmacists (27 (38.57%. Yet important adverse effects of oral contraceptive pills were not mentioned by the pharmacists except for few ones. Only twelve (17.14% pharmacists mentioned the possible interaction. There was a significant relation between the pharmacists’ gender and detection of possible interaction (p value= 0.048. Conclusion: The quality of the pharmacists’ consultations regarding the over the counter use of oral contraceptive pills was not satisfactory and required improvement.

  7. The effect of multiprofessional simulation-based obstetric team training on patient-reported quality of care : A pilot study

    NARCIS (Netherlands)

    Truijens, Sophie; Banga, F.R.; Fransen, A.F.; Pop, Victor; van Runnard Heimel, P.J.; Oei, S.G.

    2015-01-01

    Introduction: This study aimed to explore whether multiprofessional simulation-based obstetric team training improves patient-reported quality of care during pregnancy and childbirth. Methods: Multiprofessional teams from a large obstetric collaborative network in the Netherlands were trained in

  8. Recognizing, responding to and reporting patient deterioration: transferring simulation learning to patient care settings.

    Science.gov (United States)

    Liaw, Sok Ying; Chan, Sally Wai-chi; Scherpbier, Albert; Rethans, Jan-Joost; Pua, Gim Gim

    2012-03-01

    A simulation program was implemented in a pre-registration nursing curriculum for developing nursing students' performances in assessing, managing and reporting in relation to patients with physiological deterioration. To explore nursing students' experiences of how a simulation programme has prepared them to transfer their performance to clinical practice, in their encounters with deteriorating patients in ward. A qualitative study using a critical incident technique was conducted. After they had undertaken a simulation program, fifteen undergraduate nursing students, who had encountered deteriorating patients in their clinical practicum in wards were interviewed using semi-structured questionnaires. Content analysis was used to analyse the data. Four main themes emerged describing key factors influencing the transfer of simulation learning to clinical practice; memory, involving simulation learning enhanced storage and retrieval of knowledge; mnemonics as transfer tools for performing systematic physical assessment and reporting a patient's deterioration to a doctor; recognizing similar situations, where students used experiences from similar simulation situation to identify problems and initiate nursing interventions for their patients; and finally, emotional responses, that have both negative and positive impacts on transferring their simulation learning. Two other main themes emerged regarding strategies to facilitate transfer; self-directed learning for promoting the retention of simulation learning; and, realism, where simulated patients could be used to provide real-life clinical experiences. The findings provide an understanding of how a simulation program may impact on the nursing students' performances in clinical practice, which is useful information for future improvement of programmes to optimize learning and transfer effective care to patient care settings. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  9. Assessment of robotic patient simulators for training in manual physical therapy examination techniques.

    Science.gov (United States)

    Ishikawa, Shun; Okamoto, Shogo; Isogai, Kaoru; Akiyama, Yasuhiro; Yanagihara, Naomi; Yamada, Yoji

    2015-01-01

    Robots that simulate patients suffering from joint resistance caused by biomechanical and neural impairments are used to aid the training of physical therapists in manual examination techniques. However, there are few methods for assessing such robots. This article proposes two types of assessment measures based on typical judgments of clinicians. One of the measures involves the evaluation of how well the simulator presents different severities of a specified disease. Experienced clinicians were requested to rate the simulated symptoms in terms of severity, and the consistency of their ratings was used as a performance measure. The other measure involves the evaluation of how well the simulator presents different types of symptoms. In this case, the clinicians were requested to classify the simulated resistances in terms of symptom type, and the average ratios of their answers were used as performance measures. For both types of assessment measures, a higher index implied higher agreement among the experienced clinicians that subjectively assessed the symptoms based on typical symptom features. We applied these two assessment methods to a patient knee robot and achieved positive appraisals. The assessment measures have potential for use in comparing several patient simulators for training physical therapists, rather than as absolute indices for developing a standard.

  10. Simulating Space Capsule Water Landing with Explicit Finite Element Method

    Science.gov (United States)

    Wang, John T.; Lyle, Karen H.

    2007-01-01

    A study of using an explicit nonlinear dynamic finite element code for simulating the water landing of a space capsule was performed. The finite element model contains Lagrangian shell elements for the space capsule and Eulerian solid elements for the water and air. An Arbitrary Lagrangian Eulerian (ALE) solver and a penalty coupling method were used for predicting the fluid and structure interaction forces. The space capsule was first assumed to be rigid, so the numerical results could be correlated with closed form solutions. The water and air meshes were continuously refined until the solution was converged. The converged maximum deceleration predicted is bounded by the classical von Karman and Wagner solutions and is considered to be an adequate solution. The refined water and air meshes were then used in the models for simulating the water landing of a capsule model that has a flexible bottom. For small pitch angle cases, the maximum deceleration from the flexible capsule model was found to be significantly greater than the maximum deceleration obtained from the corresponding rigid model. For large pitch angle cases, the difference between the maximum deceleration of the flexible model and that of its corresponding rigid model is smaller. Test data of Apollo space capsules with a flexible heat shield qualitatively support the findings presented in this paper.

  11. Patient safety and quality of care: How may clinical simulation contribute?

    Directory of Open Access Journals (Sweden)

    Sanne Jensen

    2015-09-01

    Full Text Available The usability of health information technology (IT is increasingly recognized as critically important to the development of systems that ensure patient safety and quality of care. The substantial complexity of organizations, work practice and physical environments within the healthcare sector influences the development and application of health IT. When health IT is introduced in local clinical work practices, potential patient safety hazards and insufficient support of work practices need to be examined. Qualitative methods, such as clinical simulation, may be used to evaluate new technology in correlation with the clinical context and to study the interaction between users, technology and work practice. Compared with the “classic” methods, such as heuristic inspection and usability testing, clinical simulation takes the clinical context into account. Clinical simulation can be useful in many processes in the human-centred design cycle. In the requirement specification, clinical simulation can be useful to analyze user requirements and work practice as well to evaluate requirements. In the design of health IT, clinical simulation can be used to evaluate clinical information systems and serve as common ground to help to achieve a shared understanding between various communities of practice. In a public procurement process, a clinical simulation-based assessment can help give insight into different solutions and how they support work practice. Before organizational implementation, clinical simulation is a very suitable means, by which to assess an application in connection with work practice.

  12. Smoothed particle hydrodynamics method from a large eddy simulation perspective

    Science.gov (United States)

    Di Mascio, A.; Antuono, M.; Colagrossi, A.; Marrone, S.

    2017-03-01

    The Smoothed Particle Hydrodynamics (SPH) method, often used for the modelling of the Navier-Stokes equations by a meshless Lagrangian approach, is revisited from the point of view of Large Eddy Simulation (LES). To this aim, the LES filtering procedure is recast in a Lagrangian framework by defining a filter that moves with the positions of the fluid particles at the filtered velocity. It is shown that the SPH smoothing procedure can be reinterpreted as a sort of LES Lagrangian filtering, and that, besides the terms coming from the LES convolution, additional contributions (never accounted for in the SPH literature) appear in the equations when formulated in a filtered fashion. Appropriate closure formulas are derived for the additional terms and a preliminary numerical test is provided to show the main features of the proposed LES-SPH model.

  13. An experiment teaching method based on the Optisystem simulation platform

    Science.gov (United States)

    Zhu, Jihua; Xiao, Xuanlu; Luo, Yuan

    2017-08-01

    The experiment teaching of optical communication system is difficult to achieve because of expensive equipment. The Optisystem is optical communication system design software, being able to provide such a simulation platform. According to the characteristic of the OptiSystem, an approach of experiment teaching is put forward in this paper. It includes three gradual levels, the basics, the deeper looks and the practices. Firstly, the basics introduce a brief overview of the technology, then the deeper looks include demoes and example analyses, lastly the practices are going on through the team seminars and comments. A variety of teaching forms are implemented in class. The fact proves that this method can not only make up the laboratory but also motivate the students' learning interest and improve their practical abilities, cooperation abilities and creative spirits. On the whole, it greatly raises the teaching effect.

  14. Discrete vortex method simulations of aerodynamic admittance in bridge aerodynamics

    DEFF Research Database (Denmark)

    Rasmussen, Johannes Tophøj; Hejlesen, Mads Mølholm; Larsen, Allan

    , and to determine aerodynamic forces and the corresponding flutter limit. A simulation of the three-dimensional bridge responseto turbulent wind is carried out by quasi steady theory by modelling the bridge girder as a line like structure [2], applying the aerodynamic load coefficients found from the current version...... of DVMFLOW in a strip wise fashion. Neglecting the aerodynamic admittance, i.e. the correlation of the instantaneous lift force to the turbulent fluctuations in the vertical velocities, leads to higher response to high frequency atmospheric turbulence than would be obtained from wind tunnel tests...... velocity spectra are found in good agreement with the target spectra. The aerodynamic admittance of the structure is measured by sampling vertical velocities immediately upstream of the structure and the lift forces on the structure. The method is validated against the analytic solution for the admittance...

  15. Applying Simulation Method in Formulation of Gluten-Free Cookies

    Directory of Open Access Journals (Sweden)

    Nikitina Marina

    2017-01-01

    Full Text Available At present time priority direction in the development of new food products its developing of technology products for special purposes. These types of products are gluten-free confectionery products, intended for people with celiac disease. Gluten-free products are in demand among consumers, it needs to expand assortment, and improvement of quality indicators. At this article results of studies on the development of pastry products based on amaranth flour does not contain gluten. Study based on method of simulation recipes gluten-free confectionery functional orientation to optimize their chemical composition. The resulting products will allow to diversify and supplement the necessary nutrients diet for people with gluten intolerance, as well as for those who follow a gluten-free diet.

  16. A fast Chebyshev method for simulating flexible-wing propulsion

    Science.gov (United States)

    Moore, M. Nicholas J.

    2017-09-01

    We develop a highly efficient numerical method to simulate small-amplitude flapping propulsion by a flexible wing in a nearly inviscid fluid. We allow the wing's elastic modulus and mass density to vary arbitrarily, with an eye towards optimizing these distributions for propulsive performance. The method to determine the wing kinematics is based on Chebyshev collocation of the 1D beam equation as coupled to the surrounding 2D fluid flow. Through small-amplitude analysis of the Euler equations (with trailing-edge vortex shedding), the complete hydrodynamics can be represented by a nonlocal operator that acts on the 1D wing kinematics. A class of semi-analytical solutions permits fast evaluation of this operator with O (Nlog ⁡ N) operations, where N is the number of collocation points on the wing. This is in contrast to the minimum O (N2) cost of a direct 2D fluid solver. The coupled wing-fluid problem is thus recast as a PDE with nonlocal operator, which we solve using a preconditioned iterative method. These techniques yield a solver of near-optimal complexity, O (Nlog ⁡ N) , allowing one to rapidly search the infinite-dimensional parameter space of all possible material distributions and even perform optimization over this space.

  17. Steam generator tube rupture simulation using extended finite element method

    Energy Technology Data Exchange (ETDEWEB)

    Mohanty, Subhasish, E-mail: smohanty@anl.gov; Majumdar, Saurin; Natesan, Ken

    2016-08-15

    Highlights: • Extended finite element method used for modeling the steam generator tube rupture. • Crack propagation is modeled in an arbitrary solution dependent path. • The FE model is used for estimating the rupture pressure of steam generator tubes. • Crack coalescence modeling is also demonstrated. • The method can be used for crack modeling of tubes under severe accident condition. - Abstract: A steam generator (SG) is an important component of any pressurized water reactor. Steam generator tubes represent a primary pressure boundary whose integrity is vital to the safe operation of the reactor. SG tubes may rupture due to propagation of a crack created by mechanisms such as stress corrosion cracking, fatigue, etc. It is thus important to estimate the rupture pressures of cracked tubes for structural integrity evaluation of SGs. The objective of the present paper is to demonstrate the use of extended finite element method capability of commercially available ABAQUS software, to model SG tubes with preexisting flaws and to estimate their rupture pressures. For the purpose, elastic–plastic finite element models were developed for different SG tubes made from Alloy 600 material. The simulation results were compared with experimental results available from the steam generator tube integrity program (SGTIP) sponsored by the United States Nuclear Regulatory Commission (NRC) and conducted at Argonne National Laboratory (ANL). A reasonable correlation was found between extended finite element model results and experimental results.

  18. Simulation in interprofessional education for patient-centred collaborative care.

    Science.gov (United States)

    Baker, Cynthia; Pulling, Cheryl; McGraw, Robert; Dagnone, Jeffrey Damon; Hopkins-Rosseel, Diana; Medves, Jennifer

    2008-11-01

    This paper is a report of preliminary evaluations of an interprofessional education through simulation project by focusing on learner and teacher reactions to the pilot modules. Approaches to interprofessional education vary widely. Studies indicate, however, that active, experiential learning facilitate it. Patient simulators require learners to incorporate knowing, being and doing in action. A theoretically based competency framework was developed to guide interprofessional education using simulation. The framework includes a typology of shared, complementary and profession-specific competencies. Each competency type is associated with an intraprofessional, multiprofessional, or interprofessional teaching modality and with the professional composition of learner groups. The project is guided by an action research approach in which ongoing evaluation generates knowledge to modify and further develop it. Preliminary evaluations of the first pilot module, cardiac resuscitation rounds, among 101 nursing students, 42 medical students and 70 junior medical residents were conducted in 2005-2007 using a questionnaire with rating scales and open-ended questions. Another 20 medical students, 7 junior residents and 45 nursing students completed a questionnaire based on the Interdisciplinary Education Perception scale. Simulation-based learning provided students with interprofessional activities they saw as relevant for their future as practitioners. They embraced both the interprofessional and simulation components enthusiastically. Attitudinal scores and responses were consistently positive among both medical and nursing students. Interprofessional education through simulation offers a promising approach to preparing future healthcare professionals for the collaborative models of healthcare delivery being developed internationally.

  19. Geostatistic in Reservoir Characterization: from estimation to simulation methods

    Directory of Open Access Journals (Sweden)

    Mata Lima, H.

    2005-12-01

    Full Text Available In this article objective have been made to reviews different geostatistical methods available to estimate and simulate petrophysical properties (porosity and permeability of the reservoir. Different geostatistical techniques that allow the combination of hard and soft data are taken into account and one refers the main reason to use the geostatistical simulation rather than estimation. Uncertainty in reservoir characterization due to variogram assumption, which is a strict mathematical equation and can leads to serious simplification on description of the natural processes or phenomena under consideration, is treated here. Mutiple-point geostatistics methods based on the concept of training images, suggested by Strebelle (2000 and Caers (2003 owing to variogram limitation to capture complex heterogeneity, is another subject presented. This article intends to provide a review of geostatistical methods to serve the interest of students and researchers.Este artículo presenta una revisión de diversos métodos geoestatísticos disponibles para estimar y para simular características petrofísicas (porosidad y permeabilidad de la formación geológica (roca depósito del petróleo. Se presentan diversas técnicas geostatísticas que permiten la combinación de datos hard y soft y se explica la razón principal para utilizar la simulación geoestatística en vez de estimación. También se explica la incertidumbre en la caracterización del depósito debido a la asunción del variogram. El hecho de que el variogram sea una simple ecuación matemática conduce a la simplificación seria en la descripción de los procesos o de los fenómenos naturales bajo consideración. Los «métodos geostatísticos del Multiplepoint » (Multiple-point geostatistics methods basados en el concepto de training images, sugerido por Strebelle (2000 y Caers (2003, debido a la limitación del variogram para capturar heterogeneidad compleja es otro tema presentado. Este

  20. Transfer of learning and patient outcome in simulated crisis resource management: a systematic review.

    Science.gov (United States)

    Boet, Sylvain; Bould, M Dylan; Fung, Lillia; Qosa, Haytham; Perrier, Laure; Tavares, Walter; Reeves, Scott; Tricco, Andrea C

    2014-06-01

    Simulation-based learning is increasingly used by healthcare professionals as a safe method to learn and practice non-technical skills, such as communication and leadership, required for effective crisis resource management (CRM). This systematic review was conducted to gain a better understanding of the impact of simulation-based CRM teaching on transfer of learning to the workplace and subsequent changes in patient outcomes. Studies on CRM, crisis management, crew resource management, teamwork, and simulation published up to September 2012 were searched in MEDLINE(®), EMBASE™, CINAHL, Cochrane Central Register of Controlled Trials, and ERIC. All studies that used simulation-based CRM teaching with outcomes measured at Kirkpatrick Level 3 (transfer of learning to the workplace) or 4 (patient outcome) were included. Studies measuring only learners' reactions or simple learning (Kirkpatrick Level 1 or 2, respectively) were excluded. Two authors independently reviewed all identified titles and abstracts for eligibility. Nine articles were identified as meeting the inclusion criteria. Four studies measured transfer of simulation-based CRM learning into the clinical setting (Kirkpatrick Level 3). In three of these studies, simulation-enhanced CRM training was found significantly more effective than no intervention or didactic teaching. Five studies measured patient outcomes (Kirkpatrick Level 4). Only one of these studies found that simulation-based CRM training made a clearly significant impact on patient mortality. Based on a small number of studies, this systematic review found that CRM skills learned at the simulation centre are transferred to clinical settings, and the acquired CRM skills may translate to improved patient outcomes, including a decrease in mortality.

  1. Evaluating the practice of Iranian community pharmacists regarding oral contraceptive pills using simulated patients.

    Science.gov (United States)

    Foroutan, Nazanin; Dabaghzadeh, Fatemeh

    2016-01-01

    As oral contraceptive pills are available over the counter in pharmacies, pharmacists are professionally responsible for checking and informing patients about every aspect of taking these drugs. Simulated patient method is a new and robust way to evaluate professional performance of pharmacists. The aim of the present study was to evaluate the pharmacy practice of Iranian pharmacists regarding over-the-counter use of oral contraceptive pills using simulated patient method. Simulated patients visited pharmacy with a prescription containing ciprofloxacin and asked for oral contraceptive pills. The pharmacist was expected to ask important questions for using these drugs and to inform the patient about them properly. Moreover, the Pharmacists should advise patients in regard to the possible interaction. Ninety four pharmacists participated in this study. In 24 (25.3%) visits, the liable pharmacist was not present at the time of purchase. Furthermore, In 13 (18.57 %) visits by the simulated patients, the liable pharmacists did not pay any attention to the simulated patients even when they asked for consultation. Twenty nine (41.43%) pharmacists did not ask any question during dispensing. Nausea was the most frequent described side effect by pharmacists (27 (38.57%)). Yet important adverse effects of oral contraceptive pills were not mentioned by the pharmacists except for few ones. Only twelve (17.14%) pharmacists mentioned the possible interaction. There was a significant relation between the pharmacists' gender and detection of possible interaction (p value= 0.048). The quality of the pharmacists' consultations regarding the over the counter use of oral contraceptive pills was not satisfactory and required improvement.

  2. Quantum Simulations of Solvated Biomolecules Using Hybrid Methods

    Science.gov (United States)

    Hodak, Miroslav

    2009-03-01

    One of the most important challenges in quantum simulations on biomolecules is efficient and accurate inclusion of the solvent, because the solvent atoms usually outnumber those in the biomolecule of interest. We have developed a hybrid method that allows for explicit quantum-mechanical treatment of the solvent at low computational cost. In this method, Kohn-Sham (KS) density functional theory (DFT) is combined with an orbital-free (OF) DFT. Kohn-Sham (KS) DFT is used to describe the biomolecule and its first solvation shells, while the orbital-free (OF) DFT is employed for the rest of the solvent. The OF part is fully O(N) and capable of handling 10^5 solvent molecules on current parallel supercomputers, while taking only ˜ 10 % of the total time. The compatibility between the KS and OF DFT methods enables seamless integration between the two. In particular, the flow of solvent molecules across the KS/OF interface is allowed and the total energy is conserved. As the first large-scale applications, the hybrid method has been used to investigate the binding of copper ions to proteins involved in prion (PrP) and Parkinson's diseases. Our results for the PrP, which causes mad cow disease when misfolded, resolve a contradiction found in experiments, in which a stronger binding mode is replaced by a weaker one when concentration of copper ions is increased, and show how it can act as a copper buffer. Furthermore, incorporation of copper stabilizes the structure of the full-length PrP, suggesting its protective role in prion diseases. For alpha-synuclein, a Parkinson's disease (PD) protein, we show that Cu binding modifies the protein structurally, making it more susceptible to misfolding -- an initial step in the onset of PD. In collaboration with W. Lu, F. Rose and J. Bernholc.

  3. Improvement of Waiting Time for Patients Referring to Emergency Room Using Discrete Event Simulation

    Directory of Open Access Journals (Sweden)

    Y Zare Mehrjardi

    2011-07-01

    Full Text Available Introduction: Many simulation studies have been conducted in the hospitals and first in the emergency departments to increase the productivity. The first issue in the field of service quality and hence the patient right is “waiting time”. The goal of this study was to reduce patients waiting times, emergency service timing, modeling and improving using discrete event simulation. Methods: This was a descriptive - analytical study by the cross-sectional method on 150 patients referred to the emergency department in a public hospital. All necessary data were collected using questionnaire and through observation. Simulation model was designed using Arena software. Results: Our computer simulation model indicates that the maximum waiting time is the time waited for the test request till the results are received by the MD and also the time is necessary for the consultation and examination purposes. Among the five different scenarios, alternative 5 is more interesting economically since it requires only three additional staffs to bring down waiting times. Conclusion: According to research results, to reduce patient waiting time, the Triage processing in the emergency departments and the employment of emergency medicine expert, and the ordering of the diagnostic processes in the early stages of treatment as such as laboratory ordering for emergency patients are of main necessity.

  4. Numerical simulation for cracks detection using the finite elements method

    Directory of Open Access Journals (Sweden)

    S Bennoud

    2016-09-01

    Full Text Available The means of detection must ensure controls either during initial construction, or at the time of exploitation of all parts. The Non destructive testing (NDT gathers the most widespread methods for detecting defects of a part or review the integrity of a structure. In the areas of advanced industry (aeronautics, aerospace, nuclear …, assessing the damage of materials is a key point to control durability and reliability of parts and materials in service. In this context, it is necessary to quantify the damage and identify the different mechanisms responsible for the progress of this damage. It is therefore essential to characterize materials and identify the most sensitive indicators attached to damage to prevent their destruction and use them optimally. In this work, simulation by finite elements method is realized with aim to calculate the electromagnetic energy of interaction: probe and piece (with/without defect. From calculated energy, we deduce the real and imaginary components of the impedance which enables to determine the characteristic parameters of a crack in various metallic parts.

  5. Simulating biofilm deformation and detachment with the immersed boundary method

    CERN Document Server

    Sudarsan, Rangarajan; Stockie, John M; Eberl, Hermann J

    2015-01-01

    We apply the immersed boundary (or IB) method to simulate deformation and detachment of a periodic array of wall-bounded biofilm colonies in response to a linear shear flow. The biofilm material is represented as a network of Hookean springs that are placed along the edges of a triangulation of the biofilm region. The interfacial shear stress, lift and drag forces acting on the biofilm colony are computed by using fluid stress jump method developed by Williams, Fauci and Gaver [Disc. Contin. Dyn. Sys. B 11(2):519-540, 2009], with a modified version of their exclusion filter. Our detachment criterion is based on the novel concept of an averaged equivalent continuum stress tensor defined at each IB point in the biofilm which is then used to determine a corresponding von Mises yield stress; wherever this yield stress exceeds a given critical threshold the connections to that node are severed, thereby signalling the onset of a detachment event. In order to capture the deformation and detachment behaviour of a bio...

  6. Tsunami Simulation using CIP Method with Characteristic Curve Equations and TVD-MacCormack Method

    Science.gov (United States)

    Fukazawa, Souki; Tosaka, Hiroyuki

    2015-04-01

    After entering 21st century, we already had two big tsunami disasters associated with Mw9 earthquakes in Sumatra and Japan. To mitigate the damages of tsunami, the numerical simulation technology combined with information technologies could provide reliable predictions in planning countermeasures to prevent the damage to the social system, making safety maps, and submitting early evacuation information to the residents. Shallow water equations are still solved not only for global scale simulation of the ocean tsunami propagation but also for local scale simulation of overland inundation in many tsunami simulators though three-dimensional model starts to be used due to improvement of CPU. One-dimensional shallow water equations are below: partial bm{Q}/partial t+partial bm{E}/partial x=bm{S} in which bm{Q}=( D M )), bm{E}=( M M^2/D+gD^2/2 )), bm{S}=( 0 -gDpartial z/partial x-gn2 M|M| /D7/3 )). where D[m] is total water depth; M[m^2/s] is water flux; z[m] is topography; g[m/s^2] is the gravitational acceleration; n[s/m1/3] is Manning's roughness coefficient. To solve these, the staggered leapfrog scheme is used in a lot of wide-scale tsunami simulator. But this scheme has a problem that lagging phase error occurs when courant number is small. In some practical simulation, a kind of diffusion term is added. In this study, we developed two wide-scale tsunami simulators with different schemes and compared usual scheme and other schemes in practicability and validity. One is a total variation diminishing modification of the MacCormack method (TVD-MacCormack method) which is famous for the simulation of compressible fluids. The other is the Cubic Interpolated Profile (CIP) method with characteristic curve equations transformed from shallow water equations. Characteristic curve equations derived from shallow water equations are below: partial R_x±/partial t+C_x±partial R_x±/partial x=∓ g/2partial z/partial x in which R_x±=√{gD}± u/2, C_x±=u± √{gD}. where u

  7. Combined Visibility and Surrounding Triangles Method for Simulation of Crack Discontinuities in Meshless Methods

    Directory of Open Access Journals (Sweden)

    H. Pirali

    2012-01-01

    Full Text Available In this paper a combined node searching algorithm for simulation of crack discontinuities in meshless methods called combined visibility and surrounding triangles (CVT is proposed. The element free Galerkin (EFG method is employed for stress analysis of cracked bodies. The proposed node searching algorithm is based on the combination of surrounding triangles and visibility methods; the surrounding triangles method is used for support domains of nodes and quadrature points generated at the vicinity of crack faces and the visibility method is used for points located on the crack faces. In comparison with the conventional methods, such as the visibility, the transparency, and the diffraction method, this method is simpler with reasonable efficiency. To show the performance of this method, linear elastic fracture mechanics analyses are performed on number of standard test specimens and stress intensity factors are calculated. It is shown that the results are in good agreement with the exact solution and with those generated by the finite element method (FEM.

  8. Identifying Facilitators and Barriers for Patient Safety in a Medicine Label Design System Using Patient Simulation and Interviews

    DEFF Research Database (Denmark)

    Dieckmann, Peter; Clemmensen, Marianne Hald; Sørensen, Trine Kart

    2016-01-01

    Objectives Medicine label design plays an important role in improving patient safety. This study aimed at identifying facilitators and barriers in a medicine label system to prevent medication errors in clinical use by health care professionals. Methods The study design is qualitative...... on patient safety, it is necessary to consider the context in which they are used....... and exploratory, with a convenience sample of 10 nurses and 10 physicians from different acute care specialties working in hospitals in the Capital Region of Denmark. In 2 patient simulation scenarios and a sorting task, the participants selected the medicines from a range of ampules, vials, and infusion bags...

  9. Gradient augmented level set method for phase change simulations

    Science.gov (United States)

    Anumolu, Lakshman; Trujillo, Mario F.

    2018-01-01

    A numerical method for the simulation of two-phase flow with phase change based on the Gradient-Augmented-Level-set (GALS) strategy is presented. Sharp capturing of the vaporization process is enabled by: i) identification of the vapor-liquid interface, Γ (t), at the subgrid level, ii) discontinuous treatment of thermal physical properties (except for μ), and iii) enforcement of mass, momentum, and energy jump conditions, where the gradients of the dependent variables are obtained at Γ (t) and are consistent with their analytical expression, i.e. no local averaging is applied. Treatment of the jump in velocity and pressure at Γ (t) is achieved using the Ghost Fluid Method. The solution of the energy equation employs the sub-grid knowledge of Γ (t) to discretize the temperature Laplacian using second-order one-sided differences, i.e. the numerical stencil completely resides within each respective phase. To carefully evaluate the benefits or disadvantages of the GALS approach, the standard level set method is implemented and compared against the GALS predictions. The results show the expected trend that interface identification and transport are predicted noticeably better with GALS over the standard level set. This benefit carries over to the prediction of the Laplacian and temperature gradients in the neighborhood of the interface, which are directly linked to the calculation of the vaporization rate. However, when combining the calculation of interface transport and reinitialization with two-phase momentum and energy, the benefits of GALS are to some extent neutralized, and the causes for this behavior are identified and analyzed. Overall the additional computational costs associated with GALS are almost the same as those using the standard level set technique.

  10. A survey of modelling methods for high-fidelity wind farm simulations using large eddy simulation.

    Science.gov (United States)

    Breton, S-P; Sumner, J; Sørensen, J N; Hansen, K S; Sarmast, S; Ivanell, S

    2017-04-13

    Large eddy simulations (LES) of wind farms have the capability to provide valuable and detailed information about the dynamics of wind turbine wakes. For this reason, their use within the wind energy research community is on the rise, spurring the development of new models and methods. This review surveys the most common schemes available to model the rotor, atmospheric conditions and terrain effects within current state-of-the-art LES codes, of which an overview is provided. A summary of the experimental research data available for validation of LES codes within the context of single and multiple wake situations is also supplied. Some typical results for wind turbine and wind farm flows are presented to illustrate best practices for carrying out high-fidelity LES of wind farms under various atmospheric and terrain conditions.This article is part of the themed issue 'Wind energy in complex terrains'. © 2017 The Author(s).

  11. A survey of modelling methods for high-fidelity wind farm simulations using large eddy simulation

    Science.gov (United States)

    Breton, S.-P.; Sumner, J.; Sørensen, J. N.; Hansen, K. S.; Sarmast, S.; Ivanell, S.

    2017-03-01

    Large eddy simulations (LES) of wind farms have the capability to provide valuable and detailed information about the dynamics of wind turbine wakes. For this reason, their use within the wind energy research community is on the rise, spurring the development of new models and methods. This review surveys the most common schemes available to model the rotor, atmospheric conditions and terrain effects within current state-of-the-art LES codes, of which an overview is provided. A summary of the experimental research data available for validation of LES codes within the context of single and multiple wake situations is also supplied. Some typical results for wind turbine and wind farm flows are presented to illustrate best practices for carrying out high-fidelity LES of wind farms under various atmospheric and terrain conditions. This article is part of the themed issue 'Wind energy in complex terrains'.

  12. Advancing Virtual Patient Simulations through Design Research and InterPLAY: Part I--Design and Development

    Science.gov (United States)

    Hirumi, Atsusi; Kleinsmith, Andrea; Johnsen, Kyle; Kubovec, Stacey; Eakins, Michael; Bogert, Kenneth; Rivera-Gutierrez, Diego J.; Reyes, Ramsamooj Javier; Lok, Benjamin; Cendan, Juan

    2016-01-01

    Systematic reviews and meta-analyses of randomized controlled studies conclude that virtual patient simulations are consistently associated with higher learning outcomes compared to other educational methods. However, we cannot assume that students will learn from simply exposing students to the simulations. The instructional features that are…

  13. Parametric model of human body shape and ligaments for patient-specific epidural simulation.

    Science.gov (United States)

    Vaughan, Neil; Dubey, Venketesh N; Wee, Michael Y K; Isaacs, Richard

    2014-10-01

    This work is to build upon the concept of matching a person's weight, height and age to their overall body shape to create an adjustable three-dimensional model. A versatile and accurate predictor of body size and shape and ligament thickness is required to improve simulation for medical procedures. A model which is adjustable for any size, shape, body mass, age or height would provide ability to simulate procedures on patients of various body compositions. Three methods are provided for estimating body circumferences and ligament thicknesses for each patient. The first method is using empirical relations from body shape and size. The second method is to load a dataset from a magnetic resonance imaging (MRI) scan or ultrasound scan containing accurate ligament measurements. The third method is a developed artificial neural network (ANN) which uses MRI dataset as a training set and improves accuracy using error back-propagation, which learns to increase accuracy as more patient data is added. The ANN is trained and tested with clinical data from 23,088 patients. The ANN can predict subscapular skinfold thickness within 3.54 mm, waist circumference 3.92 cm, thigh circumference 2.00 cm, arm circumference 1.21 cm, calf circumference 1.40 cm, triceps skinfold thickness 3.43 mm. Alternative regression analysis method gave overall slightly less accurate predictions for subscapular skinfold thickness within 3.75 mm, waist circumference 3.84 cm, thigh circumference 2.16 cm, arm circumference 1.34 cm, calf circumference 1.46 cm, triceps skinfold thickness 3.89 mm. These calculations are used to display a 3D graphics model of the patient's body shape using OpenGL and adjusted by 3D mesh deformations. A patient-specific epidural simulator is presented using the developed body shape model, able to simulate needle insertion procedures on a 3D model of any patient size and shape. The developed ANN gave the most accurate results for body shape, size and ligament thickness. The

  14. Earthquake Source Simulations: A Coupled Numerical Method and Large Scale Simulations

    Science.gov (United States)

    Ely, G. P.; Xin, Q.; Faerman, M.; Day, S.; Minster, B.; Kremenek, G.; Moore, R.

    2003-12-01

    We investigate a scheme for interfacing Finite-Difference (FD) and Finite-Element (FE) models in order to simulate dynamic earthquake rupture. The more powerful but slower FE method allows for (1) unusual geometries (e.g. dipping and curved faults), (2) nonlinear physics, and (3) finite displacements. These capabilities are computationally expensive and limit the useful size of the problem that can be solved. Large efficiencies are gained by employing FE only where necessary in the near source region and coupling this with an efficient FD solution for the surrounding medium. Coupling is achieved through setting up and an overlapping buffer zone between the domains modeled by the two methods. The buffer zone is handled numerically as a set of mutual offset boundary conditions. This scheme eliminates the effect of the artificial boundaries at the interface and allows energy to propagate in both directions across the boundary. In general it is necessary to interpolate variables between the meshes and time discretizations used for each model, and this can create artifacts that must be controlled. A modular approach has been used in which either of the two component codes can be substituted with another code. We have successfully demonstrated coupling for a simulation between a second-order FD rupture dynamics code and fourth-order staggered-grid FD code. To be useful earthquake source models must capture a large range of length and time scales, which is very computationally demanding. This requires that (for current computer technology) codes must utilize parallel processing. Additionally, if larges quantities of output data are to be saved, a high performance data management system is desirable. We show results from a large scale rupture dynamics simulation designed to test these capabilities. We use second-order FD with dimensions of 400 x 800 x 800 nodes, run for 3000 time steps. Data were saved for the entire volume for three components of velocity at every time

  15. Laser method for simulating the transient radiation effects of semiconductor

    Science.gov (United States)

    Li, Mo; Sun, Peng; Tang, Ge; Wang, Xiaofeng; Wang, Jianwei; Zhang, Jian

    2017-05-01

    In this paper, we demonstrate the laser simulation adequacy both by theoretical analysis and experiments. We first explain the basic theory and physical mechanisms of laser simulation of transient radiation effect of semiconductor. Based on a simplified semiconductor structure, we describe the reflection, optical absorption and transmission of laser beam. Considering two cases of single-photon absorption when laser intensity is relatively low and two-photon absorption with higher laser intensity, we derive the laser simulation equivalent dose rate model. Then with 2 types of BJT transistors, laser simulation experiments and gamma ray radiation experiments are conducted. We found good linear relationship between laser simulation and gammy ray which depict the reliability of laser simulation.

  16. Simulation and Verificaiton of Flow in Test Methods

    DEFF Research Database (Denmark)

    Thrane, Lars Nyholm; Szabo, Peter; Geiker, Mette Rica

    2005-01-01

    Simulations and experimental results of L-box and slump flow test of a self-compacting mortar and a self-compacting concrete are compared. The simulations are based on a single fluid approach and assume an ideal Bingham behavior. It is possible to simulate the experimental results of both tests...... for a given set of rheological parameters. However, it is important to include boundary conditions related to the lifting procedure in the two tests....

  17. Efficient extrapolation methods for electro- and magnetoquasistatic field simulations

    Directory of Open Access Journals (Sweden)

    M. Clemens

    2003-01-01

    Full Text Available In magneto- and electroquasi-static time domain simulations with implicit time stepping schemes the iterative solvers applied to the large sparse (non-linear systems of equations are observed to converge faster if more accurate start solutions are available. Different extrapolation techniques for such new time step solutions are compared in combination with the preconditioned conjugate gradient algorithm. Simple extrapolation schemes based on Taylor series expansion are used as well as schemes derived especially for multi-stage implicit Runge-Kutta time stepping methods. With several initial guesses available, a new subspace projection extrapolation technique is proven to produce an optimal initial value vector. Numerical tests show the resulting improvements in terms of computational efficiency for several test problems. In quasistatischen elektromagnetischen Zeitbereichsimulationen mit impliziten Zeitschrittverfahren zeigt sich, dass die iterativen Lösungsverfahren für die großen dünnbesetzten (nicht-linearen Gleichungssysteme schneller konvergieren, wenn genauere Startlösungen vorgegeben werden. Verschiedene Extrapolationstechniken werden für jeweils neue Zeitschrittlösungen in Verbindung mit dem präkonditionierten Konjugierte Gradientenverfahren vorgestellt. Einfache Extrapolationsverfahren basierend auf Taylorreihenentwicklungen werden ebenso benutzt wie speziell für mehrstufige implizite Runge-Kutta-Verfahren entwickelte Verfahren. Sind verschiedene Startlösungen verfügbar, so erlaubt ein neues Unterraum-Projektion- Extrapolationsverfahren die Konstruktion eines optimalen neuen Startvektors. Numerische Tests zeigen die aus diesen Verfahren resultierenden Verbesserungen der numerischen Effizienz.

  18. Bayesian statistic methods and theri application in probabilistic simulation models

    Directory of Open Access Journals (Sweden)

    Sergio Iannazzo

    2007-03-01

    Full Text Available Bayesian statistic methods are facing a rapidly growing level of interest and acceptance in the field of health economics. The reasons of this success are probably to be found on the theoretical fundaments of the discipline that make these techniques more appealing to decision analysis. To this point should be added the modern IT progress that has developed different flexible and powerful statistical software framework. Among them probably one of the most noticeably is the BUGS language project and its standalone application for MS Windows WinBUGS. Scope of this paper is to introduce the subject and to show some interesting applications of WinBUGS in developing complex economical models based on Markov chains. The advantages of this approach reside on the elegance of the code produced and in its capability to easily develop probabilistic simulations. Moreover an example of the integration of bayesian inference models in a Markov model is shown. This last feature let the analyst conduce statistical analyses on the available sources of evidence and exploit them directly as inputs in the economic model.

  19. Eye tracking as a debriefing mechanism in the simulated setting improves patient safety practices.

    Science.gov (United States)

    Henneman, Elizabeth A; Cunningham, Helene; Fisher, Donald L; Plotkin, Karen; Nathanson, Brian H; Roche, Joan P; Marquard, Jenna L; Reilly, Cheryl A; Henneman, Philip L

    2014-01-01

    Human patient simulation has been widely adopted in healthcare education despite little research supporting its efficacy. The debriefing process is central to simulation education, yet alternative evaluation methods to support providing optimal feedback to students have not been well explored. Eye tracking technology is an innovative method for providing objective evaluative feedback to students after a simulation experience. The purpose of this study was to compare 3 forms of simulation-based student feedback (verbal debrief only, eye tracking only, and combined verbal debrief and eye tracking) to determine the most effective method for improving student knowledge and performance. An experimental study using a pretest-posttest design was used to compare the effectiveness of 3 types of feedback. The subjects were senior baccalaureate nursing students in their final semester enrolled at a large university in the northeast United States. Students were randomly assigned to 1 of the 3 intervention groups. All groups performed better in the posttest evaluation than in the pretest. Certain safety practices improved significantly in the eye tracking-only group. These criteria were those that required an auditory and visual comparison of 2 artifacts such as "Compares patient stated name with name on ID band." Eye tracking offers a unique opportunity to provide students with objective data about their behaviors during simulation experiences, particularly related to safety practices that involve the comparison of patient stated data to an artifact such as an ID band. Despite the limitations of current eye tracking technology, there is significant potential for the use of this technology as a method for the study and evaluation of patient safety practices.

  20. Aeroelastic large eddy simulations using vortex methods: unfrozen turbulent and sheared inflow

    DEFF Research Database (Denmark)

    Branlard, Emmanuel Simon Pierre; Papadakis, G.; Gaunaa, Mac

    2015-01-01

    Vortex particles methods are applied to the aeroelastic simulation of a wind turbine in sheared and turbulent inflow. The possibility to perform large-eddy simulations of turbulence with the effect of the shear vorticity is demonstrated for the first time in vortex methods simulations. Most vorte...

  1. Overview of Computer Simulation Modeling Approaches and Methods

    Science.gov (United States)

    Robert E. Manning; Robert M. Itami; David N. Cole; Randy Gimblett

    2005-01-01

    The field of simulation modeling has grown greatly with recent advances in computer hardware and software. Much of this work has involved large scientific and industrial applications for which substantial financial resources are available. However, advances in object-oriented programming and simulation methodology, concurrent with dramatic increases in computer...

  2. A stochastic quasi Newton method for molecular simulations

    NARCIS (Netherlands)

    Chau, Chun Dong

    2010-01-01

    In this thesis the Langevin equation with a space-dependent alternative mobility matrix has been considered. Simulations of a complex molecular system with many different length and time scales based on the fundamental equations of motion take a very long simulation time before capturing the

  3. MDMS: Molecular dynamics meta-simulator for evaluating exchange type sampling methods

    Science.gov (United States)

    Smith, Daniel B.; Okur, Asim; Brooks, Bernard R.

    2012-08-01

    Replica exchange methods have become popular tools to explore conformational space for small proteins. For larger biological systems, even with enhanced sampling methods, exploring the free energy landscape remains computationally challenging. This problem has led to the development of many improved replica exchange methods. Unfortunately, testing these methods remains expensive. We propose a molecular dynamics meta-simulator (MDMS) based on transition state theory to simulate a replica exchange simulation, eliminating the need to run explicit dynamics between exchange attempts. MDMS simulations allow for rapid testing of new replica exchange based methods, greatly reducing the amount of time needed for new method development.

  4. Clinician and simulated patient scoring - the psychometrics of a national programme recruiting dentists to DF1 training posts.

    Science.gov (United States)

    Wiskin, C M; Elley, K; Jones, E; Duffy, J

    2013-08-01

    In 2012 a national, standardised approach was taken to UK Dental Foundation 1 recruitment. Prior to that recruitment method was at the discretion of individual Deaneries. The new national system is interactive, including simulated patients to see how applicants perform in a clinical communication context. A question was whether simulated patient scores could/should be awarded as well as clinicians' scores. This paper presents score data collected in the first round of national DF1 recruitment centres, with focus on how clinical examiners and trained simulated patients rated applicants. At the live recruitment events across four national centres score data were collected from observing clinical assessors and simulated patients on the communication station. On this occasion only the clinician awarded scores 'counted', but all simulated patients completed marking sheets to enable the process to be evaluated. Data were retrospectively analysed to test the hypotheses that there would be no significant scoring differences between centres and that inter-rater reliability, by applicant, between paired clinicians, and between clinicians and simulated patients would be strong. Results showed encouraging consistency between assessors, with some differences between centres. Clinicians were more likely to offer a borderline score. In communication analyses empathy had the weakest correlation with the overall score, while professional attitude had the strongest correlation. Data supported the hypothesis that trained simulated patients can be considered as assessors. Their future inclusion offers candidates a dual perspective (clinical and non-clinical) on performance, and saves clinical time.Discussion Simulated patients scored consistently and value can be added by including different perspectives in interactive assessment. Robust training is needed in all assessor training. Simulated patients can usefully contribute to scoring in national dental recruitment centres. Lessons

  5. Multiscale optical simulation settings: challenging applications handled with an iterative ray-tracing FDTD interface method.

    Science.gov (United States)

    Leiner, Claude; Nemitz, Wolfgang; Schweitzer, Susanne; Kuna, Ladislav; Wenzl, Franz P; Hartmann, Paul; Satzinger, Valentin; Sommer, Christian

    2016-03-20

    We show that with an appropriate combination of two optical simulation techniques-classical ray-tracing and the finite difference time domain method-an optical device containing multiple diffractive and refractive optical elements can be accurately simulated in an iterative simulation approach. We compare the simulation results with experimental measurements of the device to discuss the applicability and accuracy of our iterative simulation procedure.

  6. Evaluation of the airway of the SimMan full-scale patient simulator

    DEFF Research Database (Denmark)

    Hesselfeldt, R; Kristensen, M S; Rasmussen, L S

    2005-01-01

    SimMan is a full-scale patient simulator, capable of simulating normal and pathological airways. The performance of SimMan has never been critically evaluated.......SimMan is a full-scale patient simulator, capable of simulating normal and pathological airways. The performance of SimMan has never been critically evaluated....

  7. Simulation

    DEFF Research Database (Denmark)

    Gould, Derek A; Chalmers, Nicholas; Johnson, Sheena J

    2012-01-01

    Recognition of the many limitations of traditional apprenticeship training is driving new approaches to learning medical procedural skills. Among simulation technologies and methods available today, computer-based systems are topical and bring the benefits of automated, repeatable, and reliable...... performance assessments. Human factors research is central to simulator model development that is relevant to real-world imaging-guided interventional tasks and to the credentialing programs in which it would be used....

  8. Problem-based learning using patient-simulated videos showing daily life for a comprehensive clinical approach

    OpenAIRE

    Ikegami, Akiko; Ohira, Yoshiyuki; Uehara, Takanori; Noda, Kazutaka; Suzuki, Shingo; Shikino, Kiyoshi; Kajiwara, Hideki; Kondo, Takeshi; Hirota, Yusuke; Ikusaka, Masatomi

    2017-01-01

    Objectives We examined whether problem-based learning tutorials using patient-simulated videos showing daily life are more practical for clinical learning, compared with traditional paper-based problem-based learning, for the consideration rate of psychosocial issues and the recall rate for experienced learning. Methods Twenty-two groups with 120 fifth-year students were each assigned paper-based problem-based learning and video-based problem-based learning using patient-simulated videos. We ...

  9. Working as simulated patient has effects on real patient life – Preliminary insights from a qualitative study

    Directory of Open Access Journals (Sweden)

    Simmenroth-Nayda, Anne

    2016-05-01

    Full Text Available Background: Persons who simulate patients during medical education understand the routines and the underlying script of medical consultations better. We aimed to explore how simulated patients (SPs integrated this new understanding into their daily life, how this work affected their private life as patients, and what we can learn from these changes for concepts of empowerment.Design, setting, and participants: A qualitative interview study. All SPs of Göttingen medical school who had been working longer than three semesters (n=14 were invited and agreed to take part in an open interview about their daily experience with real doctors. Documentary method was used to identify the main issues. Several cases were chosen according to maximum contrast and analysed by in-depth analysis to provide vivid examples of how simulations may affect the real life of the SPs as patients.Results: Our analysis revealed three main changes in the behaviour of SPs as real patients. They were more attentive, had a better understanding of the circumstances under which doctors work, and acted more self-confidently. From the selected cases it became apparent that working as a SP may lead to a constant and significant decrease of fear of hospitals and medical procedures or, in other cases, may enable the SPs to develop new abilities for giving feedback, questioning procedures, and explanations for real doctors.Conclusion: working as a simulated patient seems to be well-suited to understand own progression of diseases, to increase self-responsibility and to a confident attitude as patient.

  10. A novel method for fast Change-Point detection on simulated time series and electrocardiogram data.

    Directory of Open Access Journals (Sweden)

    Jin-Peng Qi

    Full Text Available Although Kolmogorov-Smirnov (KS statistic is a widely used method, some weaknesses exist in investigating abrupt Change Point (CP problems, e.g. it is time-consuming and invalid sometimes. To detect abrupt change from time series fast, a novel method is proposed based on Haar Wavelet (HW and KS statistic (HWKS. First, the two Binary Search Trees (BSTs, termed TcA and TcD, are constructed by multi-level HW from a diagnosed time series; the framework of HWKS method is implemented by introducing a modified KS statistic and two search rules based on the two BSTs; and then fast CP detection is implemented by two HWKS-based algorithms. Second, the performance of HWKS is evaluated by simulated time series dataset. The simulations show that HWKS is faster, more sensitive and efficient than KS, HW, and T methods. Last, HWKS is applied to analyze the electrocardiogram (ECG time series, the experiment results show that the proposed method can find abrupt change from ECG segment with maximal data fluctuation more quickly and efficiently, and it is very helpful to inspect and diagnose the different state of health from a patient's ECG signal.

  11. Numerical simulations of multicomponent ecological models with adaptive methods.

    Science.gov (United States)

    Owolabi, Kolade M; Patidar, Kailash C

    2016-01-08

    The study of dynamic relationship between a multi-species models has gained a huge amount of scientific interest over the years and will continue to maintain its dominance in both ecology and mathematical ecology in the years to come due to its practical relevance and universal existence. Some of its emergence phenomena include spatiotemporal patterns, oscillating solutions, multiple steady states and spatial pattern formation. Many time-dependent partial differential equations are found combining low-order nonlinear with higher-order linear terms. In attempt to obtain a reliable results of such problems, it is desirable to use higher-order methods in both space and time. Most computations heretofore are restricted to second order in time due to some difficulties introduced by the combination of stiffness and nonlinearity. Hence, the dynamics of a reaction-diffusion models considered in this paper permit the use of two classic mathematical ideas. As a result, we introduce higher order finite difference approximation for the spatial discretization, and advance the resulting system of ODE with a family of exponential time differencing schemes. We present the stability properties of these methods along with the extensive numerical simulations for a number of multi-species models. When the diffusivity is small many of the models considered in this paper are found to exhibit a form of localized spatiotemporal patterns. Such patterns are correctly captured in the local analysis of the model equations. An extended 2D results that are in agreement with Turing typical patterns such as stripes and spots, as well as irregular snakelike structures are presented. We finally show that the designed schemes are dynamically consistent. The dynamic complexities of some ecological models are studied by considering their linear stability analysis. Based on the choices of parameters in transforming the system into a dimensionless form, we were able to obtain a well-balanced system that

  12. [Innovation in healthcare processes and patient safety using clinical simulation].

    Science.gov (United States)

    Rojo, E; Maestre, J M; Díaz-Mendi, A R; Ansorena, L; Del Moral, I

    2016-01-01

    Many excellent ideas are never implemented or generalised by healthcare organisations. There are two related paradigms: thinking that individuals primarily change through accumulating knowledge, and believing that the dissemination of that knowledge within the organisation is the key element to facilitate change. As an alternative, a description and evaluation of a simulation-based inter-professional team training program conducted in a Regional Health Service to promote and facilitate change is presented. The Department of Continuing Education completed the needs assessment using the proposals presented by clinical units and management. Skills and behaviors that could be learned using simulation were selected, and all personnel from the units participating were included. Experiential learning principles based on clinical simulation and debriefing, were used for the instructional design. The Kirkpatrick model was used to evaluate the program. Objectives included: a) decision-making and teamwork skills training in high prevalence diseases with a high rate of preventable complications; b) care processes reorganisation to improve efficiency, while maintaining patient safety; and, c) implementation of new complex techniques with a long learning curve, and high preventable complications rate. Thirty clinical units organised 39 training programs in the 3 public hospitals, and primary care of the Regional Health Service during 2013-2014. Over 1,559 healthcare professionals participated, including nursing assistants, nurses and physicians. Simulation in healthcare to train inter-professional teams can promote and facilitate change in patient care, and organisational re-engineering. Copyright © 2016 SECA. Publicado por Elsevier España, S.L.U. All rights reserved.

  13. Computational simulation in architectural and environmental acoustics methods and applications of wave-based computation

    CERN Document Server

    Sakamoto, Shinichi; Otsuru, Toru

    2014-01-01

    This book reviews a variety of methods for wave-based acoustic simulation and recent applications to architectural and environmental acoustic problems. Following an introduction providing an overview of computational simulation of sound environment, the book is in two parts: four chapters on methods and four chapters on applications. The first part explains the fundamentals and advanced techniques for three popular methods, namely, the finite-difference time-domain method, the finite element method, and the boundary element method, as well as alternative time-domain methods. The second part demonstrates various applications to room acoustics simulation, noise propagation simulation, acoustic property simulation for building components, and auralization. This book is a valuable reference that covers the state of the art in computational simulation for architectural and environmental acoustics.  

  14. From multidimensional replica-exchange method to multidimensional multicanonical algorithm and simulated tempering.

    Science.gov (United States)

    Mitsutake, Ayori; Okamoto, Yuko

    2009-04-01

    We discuss multidimensional generalizations of multicanonical algorithm, simulated tempering, and replica-exchange method. We generalize the original potential-energy function E0 by adding any physical quantity V of interest as a new energy term with a coupling constant lambda. We then perform a multidimensional multicanonical simulation where a random walk in E0 and V spaces is realized. We can alternately perform a multidimensional simulated-tempering simulation where a random walk in temperature T and parameter lambda is realized. The results of the multidimensional replica-exchange simulations can be used to determine the weight factors for these multidimensional multicanonical and simulated-tempering simulations.

  15. [Effects of Training Students through a Program Simulating Medication Administration and Patient Instructions in Pre-training for Practical Training].

    Science.gov (United States)

    Kikuchi, Chigusa; Matsunaga, Tamihide; Suzuki, Tadashi

    2015-01-01

    Pharmacy school students were trained in a program simulating medication administration and giving adherence instructions. Following the training, the educational effects were evaluated. Students were separated into two groups. One group of students played the role of pharmacists and instructed simulated patients on medication adherence. Another group of students played the role of patients receiving simulated drug therapy; they were instructed on medication adherence by the students playing the role of pharmacists. The educational effects were evaluated using a questionnaire. The scores for "recognition of factors that influence medication adherence" tended to increase after the simulation, and they increased significantly after practical training. The scores for "self-evaluation of technique for instructing patients on medication adherence" increased significantly after the simulation, and they increased even more after practical training. The students' understanding of the effects on patients who were being instructed also increased significantly after the simulation, and these changes were maintained after practical training. In particular, students became more aware of the influence of pharmacists' attitudes. In practical training, the simulation training was helpful for bedside practice at hospital pharmacies and over-the-counter service at community pharmacies. Thus, the use of role play and simulated patients was an effective method for training pharmacy students to instruct patients on medication adherence.

  16. Modelling of dusty plasma properties by computer simulation methods

    Energy Technology Data Exchange (ETDEWEB)

    Baimbetov, F B [IETP, Al Farabi Kazakh National University, 96a, Tole bi St, Almaty 050012 (Kazakhstan); Ramazanov, T S [IETP, Al Farabi Kazakh National University, 96a, Tole bi St, Almaty 050012 (Kazakhstan); Dzhumagulova, K N [IETP, Al Farabi Kazakh National University, 96a, Tole bi St, Almaty 050012 (Kazakhstan); Kadyrsizov, E R [Institute for High Energy Densities of RAS, Izhorskaya 13/19, Moscow 125412 (Russian Federation); Petrov, O F [IETP, Al Farabi Kazakh National University, 96a, Tole bi St, Almaty 050012 (Kazakhstan); Gavrikov, A V [IETP, Al Farabi Kazakh National University, 96a, Tole bi St, Almaty 050012 (Kazakhstan)

    2006-04-28

    Computer simulation of dusty plasma properties is performed. The radial distribution functions, the diffusion coefficient are calculated on the basis of the Langevin dynamics. A comparison with the experimental data is made.

  17. A novel multiblock immersed boundary method for large eddy simulation of complex arterial hemodynamics

    Science.gov (United States)

    Anupindi, Kameswararao; Delorme, Yann; Shetty, Dinesh A.; Frankel, Steven H.

    2013-12-01

    Computational fluid dynamics (CFD) simulations are becoming a reliable tool to understand hemodynamics, disease progression in pathological blood vessels and to predict medical device performance. Immersed boundary method (IBM) emerged as an attractive methodology because of its ability to efficiently handle complex moving and rotating geometries on structured grids. However, its application to study blood flow in complex, branching, patient-specific anatomies is scarce. This is because of the dominance of grid nodes in the exterior of the fluid domain over the useful grid nodes in the interior, rendering an inevitable memory and computational overhead. In order to alleviate this problem, we propose a novel multiblock based IBM that preserves the simplicity and effectiveness of the IBM on structured Cartesian meshes and enables handling of complex, anatomical geometries at a reduced memory overhead by minimizing the grid nodes in the exterior of the fluid domain. As pathological and medical device hemodynamics often involve complex, unsteady transitional or turbulent flow fields, a scale resolving turbulence model such as large eddy simulation (LES) is used in the present work. The proposed solver (here after referred as WenoHemo), is developed by enhancing an existing in-house high-order incompressible flow solver that was previously validated for its numerics and several LES models by Shetty et al. (2010) [33]. In the present work, WenoHemo is systematically validated for additional numerics introduced, such as IBM and the multiblock approach, by simulating laminar flow over a sphere and laminar flow over a backward facing step respectively. Then, we validate the entire solver methodology by simulating laminar and transitional flow in abdominal aortic aneurysm (AAA). Finally, we perform blood flow simulations in the challenging clinically relevant thoracic aortic aneurysm (TAA), to gain insights into the type of fluid flow patterns that exist in pathological

  18. Improving Power System Risk Evaluation Method Using Monte Carlo Simulation and Gaussian Mixture Method

    Directory of Open Access Journals (Sweden)

    GHAREHPETIAN, G. B.

    2009-06-01

    Full Text Available The analysis of the risk of partial and total blackouts has a crucial role to determine safe limits in power system design, operation and upgrade. Due to huge cost of blackouts, it is very important to improve risk assessment methods. In this paper, Monte Carlo simulation (MCS was used to analyze the risk and Gaussian Mixture Method (GMM has been used to estimate the probability density function (PDF of the load curtailment, in order to improve the power system risk assessment method. In this improved method, PDF and a suggested index have been used to analyze the risk of loss of load. The effect of considering the number of generation units of power plants in the risk analysis has been studied too. The improved risk assessment method has been applied to IEEE 118 bus and the network of Khorasan Regional Electric Company (KREC and the PDF of the load curtailment has been determined for both systems. The effect of various network loadings, transmission unavailability, transmission capacity and generation unavailability conditions on blackout risk has been investigated too.

  19. NUMERICAL METHODS FOR THE SIMULATION OF HIGH INTENSITY HADRON SYNCHROTRONS.

    Energy Technology Data Exchange (ETDEWEB)

    LUCCIO, A.; D' IMPERIO, N.; MALITSKY, N.

    2005-09-12

    Numerical algorithms for PIC simulation of beam dynamics in a high intensity synchrotron on a parallel computer are presented. We introduce numerical solvers of the Laplace-Poisson equation in the presence of walls, and algorithms to compute tunes and twiss functions in the presence of space charge forces. The working code for the simulation here presented is SIMBAD, that can be run as stand alone or as part of the UAL (Unified Accelerator Libraries) package.

  20. Development of a simulation method for the subsea production system

    Directory of Open Access Journals (Sweden)

    Jong Hun Woo

    2014-07-01

    Full Text Available The failure of a subsea production plant could induce fatal hazards and enormous loss to human lives, environments, and properties. Thus, for securing integrated design safety, core source technologies include subsea system integration that has high safety and reliability and a technique for the subsea flow assurance of subsea production plant and subsea pipeline network fluids. The evaluation of subsea flow assurance needs to be performed considering the performance of a subsea production plant, reservoir production characteristics, and the flow characteristics of multiphase fluids. A subsea production plant is installed in the deep sea, and thus is exposed to a high-pressure/low-temperature environment. Accordingly, hydrates could be formed inside a subsea production plant or within a subsea pipeline network. These hydrates could induce serious damages by blocking the flow of subsea fluids. In this study, a simulation technology, which can visualize the system configuration of subsea production processes and can simulate stable flow of fluids, was introduced. Most existing subsea simulations have performed the analysis of dynamic behaviors for the installation of subsea facilities or the flow analysis of multiphase flow within pipes. The above studies occupy extensive research areas of the subsea field. In this study, with the goal of simulating the configuration of an entire deep sea production system compared to existing studies, a DES-based simulation technology, which can logically simulate oil production processes in the deep sea, was analyzed, and an implementation example of a simplified case was introduced.

  1. A study on the usefulness of high fidelity patient simulation in undergraduate medical education

    Directory of Open Access Journals (Sweden)

    Bikramjit Pal

    2018-01-01

    Full Text Available Introduction: Simulation is the imitation of the operation of a real-world process or system over time. Innovative simulation training solutions are now being used to train medical professionals in an attempt to reduce the number of safety concerns that have adverse effects on the patients. Objectives: (a To determine its usefulness as a teaching or learning tool for management of surgical emergencies, both in the short term and medium term by students’ perception. (b To plan future teaching methodology regarding hi-fidelity simulation based on the study outcomes and re-assessment of the current training modules. Methods: Quasi-experimental time series design with pretest-posttest interventional study. Quantitative data was analysed in terms of Mean, Standard Deviation and standard error of Mean. Statistical tests of significance like Repeated Measure of Analysis of Variance (ANOVA were used for comparisons. P value < 0.001 was considered to be statistically significant. Results: The students opined that the simulated sessions on high fidelity simulators had encouraged their active participation which was appropriate to their current level of learning. It helped them to think fast and the training sessions resembled a real life situation. The study showed that learning had progressively improved with each session of simulation with corresponding decrease in stress. Conclusion: Implementation of high fidelity simulation based learning in our Institute had been perceived favourably by a large number of students in enhancing their knowledge over time in management of trauma and surgical emergencies.

  2. Enhancing Care Transitions for Older People through Interprofessional Simulation: A Mixed Method Evaluation

    Directory of Open Access Journals (Sweden)

    Susie Sykes

    2017-11-01

    Full Text Available Introduction: The educational needs of the health and social care workforce for delivering effective integrated care are important. This paper reports on the development, pilot and evaluation of an interprofessional simulation course, which aimed to support integrated care models for care transitions for older people from hospital to home. Theory and methods: The course development was informed by a literature review and a scoping exercise with the health and social care workforce. The course ran six times and was attended by health and social care professionals from hospital and community (n = 49. The evaluation aimed to elicit staff perceptions of their learning about care transfers of older people and to explore application of learning into practice and perceived outcomes. The study used a sequential mixed method design with questionnaires completed pre (n = 44 and post (n = 47 course and interviews (n = 9 2–5 months later. Results: Participants evaluated interprofessional simulation as a successful strategy. Post-course, participants identified learning points and at the interviews, similar themes with examples of application in practice were: Understanding individual needs and empathy; Communicating with patients and families; Interprofessional working; Working across settings to achieve effective care transitions. Conclusions and discussion: An interprofessional simulation course successfully brought together health and social care professionals across settings to develop integrated care skills and improve care transitions for older people with complex needs from hospital to home.

  3. Immersed boundary peridynamics (IB/PD) method to simulate aortic dissection

    Science.gov (United States)

    Bhalla, Amneet Pal Singh; Griffith, Boyce

    2016-11-01

    Aortic dissection occurs when an intimal tear in the aortic wall propagates into the media to form a false lumen within the vessel wall. Rupture of the false lumen and collapse of the true lumen both carry a high risk of morbidity and mortality. Surgical treatment consists of either replacement of a portion of the aorta, or stent implantation to cover the affected segment. Both approaches carry significant risks: open surgical intervention is highly invasive, whereas stents can be challenging to implant and offer unclear long-term patient outcomes. It is also difficult to time optimally the intervention to ensure that the benefits of treatment outweigh its risks. In this work we develop innovative fluid-structure interaction (FSI) model combining elements from immersed boundary (IB) and peridynamics (PD) methods to simulate tears in membranes. The new approach is termed as IB/PD method. We use non-ordinary state based PD to represent material hyperelasticity. Several test problems are taken to validate peridynamics approach to model structural dynamics, with and without accounting for failure in the structures. FSI simulations using IB/PD method are compared with immersed finite element method (IB/FE) to validate the new hybrid approach. NIH Award R01HL117163 NSF Award ACI 1450327.

  4. Selecting a dynamic simulation modeling method for health care delivery research-part 2: report of the ISPOR Dynamic Simulation Modeling Emerging Good Practices Task Force.

    Science.gov (United States)

    Marshall, Deborah A; Burgos-Liz, Lina; IJzerman, Maarten J; Crown, William; Padula, William V; Wong, Peter K; Pasupathy, Kalyan S; Higashi, Mitchell K; Osgood, Nathaniel D

    2015-03-01

    In a previous report, the ISPOR Task Force on Dynamic Simulation Modeling Applications in Health Care Delivery Research Emerging Good Practices introduced the fundamentals of dynamic simulation modeling and identified the types of health care delivery problems for which dynamic simulation modeling can be used more effectively than other modeling methods. The hierarchical relationship between the health care delivery system, providers, patients, and other stakeholders exhibits a level of complexity that ought to be captured using dynamic simulation modeling methods. As a tool to help researchers decide whether dynamic simulation modeling is an appropriate method for modeling the effects of an intervention on a health care system, we presented the System, Interactions, Multilevel, Understanding, Loops, Agents, Time, Emergence (SIMULATE) checklist consisting of eight elements. This report builds on the previous work, systematically comparing each of the three most commonly used dynamic simulation modeling methods-system dynamics, discrete-event simulation, and agent-based modeling. We review criteria for selecting the most suitable method depending on 1) the purpose-type of problem and research questions being investigated, 2) the object-scope of the model, and 3) the method to model the object to achieve the purpose. Finally, we provide guidance for emerging good practices for dynamic simulation modeling in the health sector, covering all aspects, from the engagement of decision makers in the model design through model maintenance and upkeep. We conclude by providing some recommendations about the application of these methods to add value to informed decision making, with an emphasis on stakeholder engagement, starting with the problem definition. Finally, we identify areas in which further methodological development will likely occur given the growing "volume, velocity and variety" and availability of "big data" to provide empirical evidence and techniques

  5. Simulated-tempering replica-exchange method for the multidimensional version.

    Science.gov (United States)

    Mitsutake, Ayori

    2009-09-07

    In this article, the general formulation of the multidimensional simulated-tempering replica-exchange method is described. In previous works, the one-dimensional replica-exchange simulated-tempering and simulated-tempering replica-exchange methods were developed. For the former method, the weight factor of the one-dimensional simulated tempering is determined by a short replica-exchange simulation and multiple-histogram reweighing techniques. For the latter method, the production run is a replica-exchange simulation with a few replicas not in the canonical ensembles but in the simulated-tempering ensembles which cover wide ranges of temperature. Recently, the general formulation of the multidimensional replica-exchange simulated tempering was presented. In this article, the extension of the simulated-tempering replica-exchange method for the multidimensional version is given. As an example of applications of the algorithm, a two-dimensional replica-exchange simulation and two simulated-tempering replica-exchange simulations have been performed. Here, an alpha-helical peptide system with a model solvent has been used for the applications.

  6. Discrete vortex method simulations of the aerodynamic admittance in bridge aerodynamics

    DEFF Research Database (Denmark)

    Rasmussen, Johannes Tophøj; Hejlesen, Mads Mølholm; Larsen, Allan

    2010-01-01

    We present a novel method for the simulation of the aerodynamic admittance in bluff body aerodynamics. The method introduces a model for describing oncoming turbulence in two-dimensional discrete vortex method simulations by seeding the upstream flow with vortex particles. The turbulence...

  7. The Simulation and Analysis of the Closed Die Hot Forging Process by A Computer Simulation Method

    Directory of Open Access Journals (Sweden)

    Dipakkumar Gohil

    2012-06-01

    Full Text Available The objective of this research work is to study the variation of various parameters such as stress, strain, temperature, force, etc. during the closed die hot forging process. A computer simulation modeling approach has been adopted to transform the theoretical aspects in to a computer algorithm which would be used to simulate and analyze the closed die hot forging process. For the purpose of process study, the entire deformation process has been divided in to finite number of steps appropriately and then the output values have been computed at each deformation step. The results of simulation have been graphically represented and suitable corrective measures are also recommended, if the simulation results do not agree with the theoretical values. This computer simulation approach would significantly improve the productivity and reduce the energy consumption of the overall process for the components which are manufactured by the closed die forging process and contribute towards the efforts in reducing the global warming.

  8. Simulating Social Networks of Online Communities: Simulation as a Method for Sociability Design

    Science.gov (United States)

    Ang, Chee Siang; Zaphiris, Panayiotis

    We propose the use of social simulations to study and support the design of online communities. In this paper, we developed an Agent-Based Model (ABM) to simulate and study the formation of social networks in a Massively Multiplayer Online Role Playing Game (MMORPG) guild community. We first analyzed the activities and the social network (who-interacts-with-whom) of an existing guild community to identify its interaction patterns and characteristics. Then, based on the empirical results, we derived and formalized the interaction rules, which were implemented in our simulation. Using the simulation, we reproduced the observed social network of the guild community as a means of validation. The simulation was then used to examine how various parameters of the community (e.g. the level of activity, the number of neighbors of each agent, etc) could potentially influence the characteristic of the social networks.

  9. Teaching clinical opioid pharmacology with the Human Patient Simulator.

    Science.gov (United States)

    Hassan, Zaki; DiLorenzo, Amy; Sloan, Paul

    2010-01-01

    Postoperative pain should be aggressively treated to decrease the development of chronic postsurgical pain. There has been an increase in the use of Human Patient Simulator (HPS) for teaching advanced courses in pharmacology to medical students, residents, and nurses. The aim of this educational investigation was to pilot the HPS for the training of medical students and surgical recovery room staff nurses in the pharmacology of opioids for the management of postoperative pain. The computerized HPS mannequin is fully monitored with appropriate displays and includes a voice speaker mounted in the head. Medical students and Postanesthesia care unit nurses, led by faculty in the Department of Anesthesiology in small groups of 4-6, participated in a 2- to 3-hour HPS course on the use of opioids for the management of acute postoperative pain. Trainees were asked to treat the acute and severe postoperative pain of a simulated patient. Opioid effects and side effects (such as respiratory depression) were presented on the mannequin in real time to the participants. Side effects of naloxone to reverse opioid depression were presented as a crisis in real time to the participants. Participants completed a 10-item course evaluation using a 5-point Likert scale (1 = strongly disagree; 5 = strongly agree). Twenty-two nurses and nine medical students completed the HPS opioid pharmacology scenario. Almost all participants rated the HPS course very highly and rated every item as either agree or strongly agree. Most participants agreed that the simulator session improved their understanding of opioid pharmacology including opioid side effects and management of opioid complications. Course participants felt most strongly (median, interquartile range) that the simulator session improved their understanding of naloxone pharmacology (5, 0), simulators serve as a useful teaching tool (5, 0), and that they would be pleased to participate in any additional HPS teaching sessions (5, 0). The

  10. Computational simulation of postoperative pulmonary flow distribution in Alagille patients with peripheral pulmonary artery stenosis.

    Science.gov (United States)

    Yang, Weiguang; Hanley, Frank L; Chan, Frandics P; Marsden, Alison L; Vignon-Clementel, Irene E; Feinstein, Jeffrey A

    2017-12-01

    Up to 90% of individuals with Alagille syndrome have congenital heart diseases. Peripheral pulmonary artery stenosis (PPS), resulting in right ventricular hypertension and pulmonary flow disparity, is one of the most common abnormalities, yet the hemodynamic effects are ill-defined, and optimal patient management and treatment strategies are not well established. The purpose of this pilot study is to use recently refined computational simulation in the setting of multiple surgical strategies, to examine the influence of pulmonary artery reconstruction on hemodynamics in this population. Based on computed tomography angiography and cardiac catheterization data, preoperative pulmonary artery models were constructed for 4 patients with Alagille syndrome with PPS (all male, age range: 0.6-2.9 years), and flow simulations with deformable walls were performed. Surgeon directed virtual surgery, mimicking the surgical procedure, was then performed to derive postoperative models. Postoperative simulation-derived hemodynamics and blood flow distribution were then compared with the clinical results. Simulations confirmed substantial resistance, resulting from preoperative severe ostial stenoses, and the use of newly developed adaptive outflow boundary conditions led to excellent agreement with in vivo measurements. Relief of PPS decreased pulmonary artery pressures and improved pulmonary flow distribution both in vivo and in silico with good correlation. Using adaptive outflow boundary conditions, computational simulations can estimate postoperative overall pulmonary flow distribution in patients with Alagille syndrome after pulmonary artery reconstruction. Obstruction relief along with pulmonary artery vasodilation determines postoperative pulmonary flow distribution and newer methods can incorporate these physiologic changes. Evolving blood flow simulations may be useful in surgical or transcatheter planning and in understanding the complex interplay among various

  11. A comprehensive validation of patient-specific CFD simulations of cerebral aneurysm flow with virtual angiography

    Science.gov (United States)

    Sun, Qi; Groth, Alexandra; Bertram, Matthias; Brina, Olivier; Pereira, Vitor Mendes; Aach, Til

    2011-03-01

    Recently, image-based computational fluid dynamic simulations (CFD) have been proposed to investigate the local hemodynamics inside human cerebral aneurysms. It is suggested that the knowledge of the computed three-dimensional flow fields can be used to assist clinical risk assessment and treatment decision making. However, the reliability of CFD for accurately representing the human cerebral blood flow is difficult to assess due to the impossibility of ground truth measurements. A recently proposed virtual angiography method has been used to indirectly validate CFD results by comparing virtually constructed and clinically acquired angiograms. However, the validations are not yet comprehensive as they lack either from patient-specific boundary conditions (BCs) required for CFD simulations or from quantitative comparison methods. In this work, a simulation pipeline is built up including image-based geometry reconstruction, CFD simulations solving the dynamics of blood flow and contrast agent (CA), and virtual angiogram generation. In contrast to previous studies, the patient-specific blood flow rates obtained by transcranial color coded Doppler (TCCD) ultrasound are used to impose CFD BCs. Quantitative measures are defined to thoroughly evaluate the correspondence between the clinically acquired and virtually constructed angiograms, and thus, the reliability of CFD simulations. Exemplarily, two patient cases are presented. Close similarities are found in terms of spatial and temporal variations of CA distribution between acquired and virtual angiograms. Besides, for both patient cases, discrepancies of less than 15% are found for the relative root mean square errors (rRMSE) in time intensity curve (TIC) comparisons from selected characteristic positions.

  12. Application of Model-Based Signal Processing Methods to Computational Electromagnetics Simulators

    National Research Council Canada - National Science Library

    Ling, Hao

    2000-01-01

    This report summarizes the scientific progress on the research grant "Application of Model-Based Signal Processing Methods to Computational Electromagnetics Simulators" during the period 1 December...

  13. Annual Report on Application of Model-Based Signal Processing Methods to Computational Electromagnetics Simulators

    National Research Council Canada - National Science Library

    Ling, Hao

    1998-01-01

    This report summarizes the scientific progress on the research grant "Application of Model-Based Signal Processing Methods to Computational Electromagnetics Simulators" during the period 1 December...

  14. Application of Model-Based Signal Processing Methods to Computational Electromagnetics Simulators

    National Research Council Canada - National Science Library

    Ling, Hao

    1999-01-01

    This report summarizes the scientific progress on the research grant "Application of Model-Based Signal Processing Methods to Computational Electromagnetics Simulators" during the period 1 December...

  15. Simulating images seen by patients with inhomogeneous sensitivity losses.

    Science.gov (United States)

    Capilla, Pascual; Luque, M José; de Fez, M Dolores; García-Domene, M Carmen; Díez-Ajenjo, M Amparo

    2012-10-01

    We aim to simulate how colored images are perceived by subjects with local achromatic and chromatic contrast sensitivity losses in the visual field (VF). The spatiochromatic corresponding pair algorithm, introduced in a previous article (J Opt Soc Am (A) 2004;21:176-186), has been implemented with a linear model of the visual system. Spatial information is processed separately by the chromatic and achromatic mechanisms by means of a multiscale model, with sensors selective to frequency, orientation, and spatial position, whose mechanism-dependent relative weights change with the spatial location of the image. These weights have been obtained from perimetric data from a patient with Leber's Hereditary Optic Neuropathy and an age-matched sample of normal subjects, using achromatic, red-green, and blue-yellow gratings of different spatial frequencies. Distortion contours for each mechanism have been derived from the images simulating the perception of these subjects at different locations in the VF. The images simulating the perception of normal subjects at different locations of the VF show a fast decrease in image quality with eccentricity. The same analysis carried out with the Leber's Hereditary Optic Neuropathy patient reveals worse overall image quality throughout the VF, plus a color vision defect resembling red-green dichromacy at fovea and trichromatic anomaly in the rest of the VF. In the present article, we show that implementing the algorithm with a spatial vision model that considers the changes in contrast sensitivity with spatial location of the stimulus may reveal the local effects that are suffered, in general, by pathological subjects, and that are ignored by simpler spatial vision models.

  16. Assessment and management of serotonin syndrome in a simulated patient study of Australian community pharmacies

    Directory of Open Access Journals (Sweden)

    MacFarlane B

    2016-06-01

    Full Text Available Background: The incidence of serotonin syndrome is increasing due to the widening use of serotonergic drugs. Identification of serotonin syndrome is challenging as the manifestations are diverse. Misdiagnosis can lead to delay in care and inappropriate treatment. Objectives: The objectives of this study were to determine if staff of community pharmacies in Australia could identify the symptoms of serotonin syndrome in simulated patients and recommend an appropriate course of action. Methods: Agents acting on behalf of a simulated patient were trained on a patient scenario that reflected possible serotonin syndrome due to an interaction between duloxetine and recently prescribed tramadol. They entered 148 community pharmacies in Australia to ask for advice about a 60 year old male simulated patient who was ‘not feeling well’. The interaction was audio recorded and analysed for degree of access to the pharmacist, information gathered by pharmacy staff, management advice given and pharmacotherapy recommended. Results: The simulated patient’s agent was consulted by a pharmacist in 94.0% (139/148 of cases. The potential for serotonin syndrome was identified by 35.1% (52/148 of pharmacies. Other suggested causes of the simulated patient’s symptoms were viral (16.9%; 25/148 and cardiac (15.5%; 23/148. A total of 33.8% (50/148 of pharmacies recommended that the simulated patient should cease taking tramadol. This advice always came from the pharmacist. Immediate cessation of tramadol was advised by 94.2% (49/52 of pharmacists correctly identifying serotonin syndrome. The simulated patient was advised to seek urgent medical care in 14.2% (21/148 of cases and follow up with a doctor when possible in 68.2% (101/148 of cases. The majority of pharmacies (87.8%; 130/148 did not recommend non-prescription medicines. Conclusion: While not identifying the cause of the simulated patient’s symptoms in the majority of cases, community pharmacies

  17. Simulation-based Advance Patient Scheduling of Operating Theatres

    DEFF Research Database (Denmark)

    Andersen, Anders Reenberg; Stidsen, Thomas Jacob Riis; Nielsen, Bo Friis

    2017-01-01

    is a Markov decision process, where patients are allocated to a date and room on a daily basis. By assuming that both state and action space is only partially observable, we apply our model in an on-line scheme known as rollout, where actions are constructed using a heuristic search method. Our objective...

  18. Population pharmacodynamic modeling and simulation of the respiratory effect of acetazolamide in decompensated COPD patients.

    Directory of Open Access Journals (Sweden)

    Nicholas Heming

    Full Text Available BACKGROUND: Chronic obstructive pulmonary disease (COPD patients may develop metabolic alkalosis during weaning from mechanical ventilation. Acetazolamide is one of the treatments used to reverse metabolic alkalosis. METHODS: 619 time-respiratory (minute ventilation, tidal volume and respiratory rate and 207 time-PaCO2 observations were obtained from 68 invasively ventilated COPD patients. We modeled respiratory responses to acetazolamide in mechanically ventilated COPD patients and then simulated the effect of increased amounts of the drug. RESULTS: The effect of acetazolamide on minute ventilation and PaCO2 levels was analyzed using a nonlinear mixed effect model. The effect of different ventilatory modes was assessed on the model. Only slightly increased minute ventilation without decreased PaCO2 levels were observed in response to 250 to 500 mg of acetazolamide administered twice daily. Simulations indicated that higher acetazolamide dosage (>1000 mg daily was required to significantly increase minute ventilation (P0.75 L min(-1 in 60% of the population. The model also predicts that 45% of patients would have a decrease of PaCO2>5 mmHg with doses of 1000 mg per day. CONCLUSIONS: Simulations suggest that COPD patients might benefit from the respiratory stimulant effect after the administration of higher doses of acetazolamide.

  19. A Ten-Step Design Method for Simulation Games in Logistics Management

    NARCIS (Netherlands)

    Fumarola, M.; Van Staalduinen, J.P.; Verbraeck, A.

    2011-01-01

    Simulation games have often been found useful as a method of inquiry to gain insight in complex system behavior and as aids for design, engineering simulation and visualization, and education. Designing simulation games are the result of creative thinking and planning, but often not the result of a

  20. Adaptive Multiscale Finite Element Method for Subsurface Flow Simulation

    NARCIS (Netherlands)

    Van Esch, J.M.

    2010-01-01

    Natural geological formations generally show multiscale structural and functional heterogeneity evolving over many orders of magnitude in space and time. In subsurface hydrological simulations the geological model focuses on the structural hierarchy of physical sub units and the flow model addresses

  1. USE OF ENERGY METHOD TO SIMULATE THE PERFORMANCE ...

    African Journals Online (AJOL)

    IMECEO4, ASME-conference Nov. 13-20, Anaheim California, USA. [10] Grossman, G.; Zaltash, A.; (2001). ABSIM - Modular simulation of advanced absorption system,. International J. of Refrigeration. (24), 531 – 543. [11] Keith, E. H; Radermacher R.; Klein. S.; (1996), Absorption Chillers and. Heat pumps, CRC Press, ...

  2. Crop canopy BRDF simulation and analysis using Monte Carlo method

    NARCIS (Netherlands)

    Huang, J.; Wu, B.; Tian, Y.; Zeng, Y.

    2006-01-01

    This author designs the random process between photons and crop canopy. A Monte Carlo model has been developed to simulate the Bi-directional Reflectance Distribution Function (BRDF) of crop canopy. Comparing Monte Carlo model to MCRM model, this paper analyzes the variations of different LAD and

  3. The Simulation of the Recharging Method Based on Solar Radiation for an Implantable Biosensor.

    Science.gov (United States)

    Li, Yun; Song, Yong; Kong, Xianyue; Li, Maoyuan; Zhao, Yufei; Hao, Qun; Gao, Tianxin

    2016-09-10

    A method of recharging implantable biosensors based on solar radiation is proposed. Firstly, the models of the proposed method are developed. Secondly, the recharging processes based on solar radiation are simulated using Monte Carlo (MC) method and the energy distributions of sunlight within the different layers of human skin have been achieved and discussed. Finally, the simulation results are verified experimentally, which indicates that the proposed method will contribute to achieve a low-cost, convenient and safe method for recharging implantable biosensors.

  4. Patient safety and quality of care: how may clinical simulation contribute?

    DEFF Research Database (Denmark)

    Jensen, Sanne

    2015-01-01

    The usability of health information technology (IT) is increasingly recognized as critically important to the development of systems that ensure patient safety and quality of care. The substantial complexity of organizations, work practice and physical environments within the healthcare sector...... influences the development and application of health IT. When health IT is introduced in local clinical work practices, potential patient safety hazards and insufficient support of work practices need to be examined. Qualitative methods, such as clinical simulation, may be used to evaluate new technology...

  5. Radiant Ceiling Panels Combined with Localized Methods for Improved Thermal Comfort of Both Patient and Medical Staff in Patient Room

    DEFF Research Database (Denmark)

    Mori, Sakura; Barova, Mariya; Bolashikov, Zhecho Dimitrov

    2012-01-01

    The objectives were to identify whether ceiling installed radiant heating panels can provide thermal comfort to the occupants in a patient room, and to determine a method for optimal thermal environment to both patient and medical staff simultaneously. The experiments were performed in a climate...... chamber resembling a single-bed patient room under convective air conditioning alone or combined with the ceiling installed radiant heating panels. Two thermal manikins simulated a patient lying in the bed and a doctor standing next to the patient. Conventional cotton blanket, electric blanket, electric...... mattress were used to provide local heating for the patient. The effects of the methods were identified by comparing the manikin based equivalent temperatures. The optimal thermal comfort level for both patient and medical staff would obtained when two conventional cotton blankets were used with extra...

  6. Conceptualising patient empowerment: a mixed methods study

    NARCIS (Netherlands)

    Bravo, P.; Edwards, A.; Barr, P.J.; Scholl, I.; Elwyn, G.; Mcallister, M.

    2015-01-01

    BACKGROUND: In recent years, interventions and health policy programmes have been established to promote patient empowerment, with a particular focus on patients affected by long-term conditions. However, a clear definition of patient empowerment is lacking, making it difficult to assess

  7. Numerical simulation of GEW equation using RBF collocation method

    Directory of Open Access Journals (Sweden)

    Hamid Panahipour

    2012-08-01

    Full Text Available The generalized equal width (GEW equation is solved numerically by a meshless method based on a global collocation with standard types of radial basis functions (RBFs. Test problems including propagation of single solitons, interaction of two and three solitons, development of the Maxwellian initial condition pulses, wave undulation and wave generation are used to indicate the efficiency and accuracy of the method. Comparisons are made between the results of the proposed method and some other published numerical methods.

  8. Accurate numerical methods for micromagnetics simulations with general geometries

    CERN Document Server

    García-Cervera, C J

    2003-01-01

    In current FFT-based algorithms for micromagnetics simulations, the boundary is typically replaced by a staircase approximation along the grid lines, either eliminating the incomplete cells or replacing them by complete cells. Sometimes the magnetizations at the boundary cells are weighted by the volume of the sample in the corresponding cell. We show that this leads to large errors in the computed exchange and stray fields. One consequence of this is that the predicted switching mechanism depends sensitively on the orientation of the numerical grid. We present a boundary-corrected algorithm to efficiently and accurately handle the incomplete cells at the boundary. We show that this boundary-corrected algorithm greatly improves the accuracy in micromagnetics simulations. We demonstrate by using A. Arrott's example of a hexagonal element that the switching mechanism is predicted independently of the grid orientation.

  9. Simulation methods for multiperiodic and aperiodic nanostructured dielectric waveguides

    DEFF Research Database (Denmark)

    Paulsen, Moritz; Neustock, Lars Thorben; Jahns, Sabrina

    2017-01-01

    on Rudin–Shapiro, Fibonacci, and Thue–Morse binary sequences. The near-field and far-field properties are computed employing the finite-element method (FEM), the finite-difference time-domain (FDTD) method as well as a rigorous coupled wave algorithm (RCWA). The results show that all three methods...

  10. Fast Multilevel Panel Method for Wind Turbine Rotor Flow Simulations

    NARCIS (Netherlands)

    van Garrel, Arne; Venner, Cornelis H.; Hoeijmakers, Hendrik Willem Marie

    2017-01-01

    A fast multilevel integral transform method has been developed that enables the rapid analysis of unsteady inviscid flows around wind turbines rotors. A low order panel method is used and the new multi-level multi-integration cluster (MLMIC) method reduces the computational complexity for

  11. A Framework for Simulation Validation & Verification Method Selection

    NARCIS (Netherlands)

    Roungas, V.; Meijer, S.A.; Verbraeck, A.; Ramezani, Arash; Williams, Edward; Bauer, Marek

    2017-01-01

    Thirty years of research on validation and verification (V\\&V) has returned a plethora of methods, statistical techniques, and reported case studies. It is that abundance of methods that poses a major challenge. Because of overlap between methods and time and budget constraints, it is impossible

  12. Changing the Paradigm: Simulation, a Method of First Resort

    Science.gov (United States)

    2011-09-01

    Analysis System COCOM Combatant Commander COSMOS C4ISR Space and Missile Operations Simulation CPU Central Processing Unit CSV Comma-Separated Values...the outputs of the model during the course of the model development without having to export the results and interpret the results using additional...of each scenario run as desired, with the output of all readily available to either view within Simio or be exported to a comma-separated values

  13. Geometry optimization of zirconium sulfophenylphosphonate layers by molecular simulation methods

    Czech Academy of Sciences Publication Activity Database

    Škoda, J.; Pospíšil, M.; Kovář, P.; Melánová, Klára; Svoboda, J.; Beneš, L.; Zima, Vítězslav

    2018-01-01

    Roč. 24, č. 1 (2018), s. 1-12, č. článku 10. ISSN 1610-2940 R&D Projects: GA ČR(CZ) GA14-13368S; GA ČR(CZ) GA17-10639S Institutional support: RVO:61389013 Keywords : zirconium sulfophenylphosphonate * intercalation * molecular simulation Subject RIV: CA - Inorganic Chemistry OBOR OECD: Inorganic and nuclear chemistry Impact factor: 1.425, year: 2016

  14. Simulation Method of Cumulative Flow without of Axial Stagnation Point

    Directory of Open Access Journals (Sweden)

    I. V. Minin

    2015-01-01

    Full Text Available The paper describes a developed analytical model of non-stationary formation of a cumulative jet without axial stagnation point. It shows that it is possible to control the weight, size, speed, and momentum of the jet with the parameters, which are not achievable in the classical mode of jet formation. Considered jet formation principle can be used to conduct laboratory simulation of astro-like plasma jets.

  15. A Simple Graphical Method for Quantification of Disaster Management Surge Capacity Using Computer Simulation and Process-control Tools.

    Science.gov (United States)

    Franc, Jeffrey Michael; Ingrassia, Pier Luigi; Verde, Manuela; Colombo, Davide; Della Corte, Francesco

    2015-02-01

    Surge capacity, or the ability to manage an extraordinary volume of patients, is fundamental for hospital management of mass-casualty incidents. However, quantification of surge capacity is difficult and no universal standard for its measurement has emerged, nor has a standardized statistical method been advocated. As mass-casualty incidents are rare, simulation may represent a viable alternative to measure surge capacity. Hypothesis/Problem The objective of the current study was to develop a statistical method for the quantification of surge capacity using a combination of computer simulation and simple process-control statistical tools. Length-of-stay (LOS) and patient volume (PV) were used as metrics. The use of this method was then demonstrated on a subsequent computer simulation of an emergency department (ED) response to a mass-casualty incident. In the derivation phase, 357 participants in five countries performed 62 computer simulations of an ED response to a mass-casualty incident. Benchmarks for ED response were derived from these simulations, including LOS and PV metrics for triage, bed assignment, physician assessment, and disposition. In the application phase, 13 students of the European Master in Disaster Medicine (EMDM) program completed the same simulation scenario, and the results were compared to the standards obtained in the derivation phase. Patient-volume metrics included number of patients to be triaged, assigned to rooms, assessed by a physician, and disposed. Length-of-stay metrics included median time to triage, room assignment, physician assessment, and disposition. Simple graphical methods were used to compare the application phase group to the derived benchmarks using process-control statistical tools. The group in the application phase failed to meet the indicated standard for LOS from admission to disposition decision. This study demonstrates how simulation software can be used to derive values for objective benchmarks of ED surge

  16. [Actor as a simulated patient in medical education at the University of Pécs].

    Science.gov (United States)

    Koppán, Ágnes; Eklicsné Lepenye, Katalin; Halász, Renáta; Sebők, Judit; Szemán, Eszter; Németh, Zsuzsanna; Rendeki, Szilárd

    2017-07-01

    Medical training in the 21st century faces simulation-based education as one of the challenges that efficiently contributes to clinical skills development while moderating the burden on the clinicians and patients alike. The University of Pécs, Medical School has launched a simulation program in the MediSkillsLab based on history taking with actors to improve patient interviewing communication skills. This new program was inspired by experiences gathered in previous medical language teaching and integrates the method of the "Standardized Patient Program". The method has been applied in America since the 1960s. This is the first time the program has been introduced in Hungary and implemented in an interdisciplinary design, where medical specialists, linguists, actor-patients and medical students collaborate to improve professional, language and communicative competence of the students. A course like this has its pivotal role in the medical training, and as a result more efficient and patient-oriented communication may take place at the clinical setting. Orv Hetil. 2017; 158(26): 1022-1027.

  17. Comparison of biochemical simulations using integrators derived from "Adomian" decomposition with traditional numerical methods.

    Science.gov (United States)

    Bulliman, B T; Kuchel, P W

    1990-01-01

    Comparisons are made between some traditional numerical integrators and integration using "Adomian" power series solutions to the ordinary differential equations. These are initial investigations to determine the viability of their application to the simulation of large complex metabolic pathways. A small set of test equations was employed to represent the types of problems encountered in biochemical applications. It was found that the "Adomian" method is as accurate as the numerical methods and, for 'nonstiff' equations or for small simulation times, the "Adomian" method is often more efficient. The results suggest that it may be worthwhile refining this method for biochemical simulations for situations where the traditional numerical methods fail.

  18. Development and Analysis of Train Brake Curve Calculation Methods with Complex Simulation

    Directory of Open Access Journals (Sweden)

    Geza Tarnai

    2006-01-01

    Full Text Available This paper describes an efficient method using simulation for developing and analyzing train brake curve calculation methods for the on-board computer of the ETCS system. An application example with actual measurements is also presented.

  19. Family Medicine Residents' Performance with Detected Versus Undetected Simulated Patients Posing as Problem Drinkers.

    Science.gov (United States)

    Kahan, Meldon; Liu, Eleanor; Borsoi, Diane; Wilson, Lynn; Brewster, Joan M; Sobell, Mark B; Sobell, Linda C

    2004-12-01

    Simulated patients are commonly used to evaluate medical trainees. Unannounced simulated patients provide an accurate measure of physician performance. To determine the effects of detection of SPs on physician performance, and identify factors leading to detection. Fixty-six family medicine residents were each visited by two unannounced simulated patients presenting with alcohol-induced hypertension or insomnia. Residents were then surveyed on their detection of SPs. SPs were detected on 45 out of 104 visits. Inner city clinics had higher detection rates than middle class clinics. Residents' checklist and global rating scores were substantially higher on detected than undetected visits, for both between-subject and within-subject comparisons. The most common reasons for detection concerned SP demographics and behaviour; the SP "did not act like a drinker" and was of a different social class than the typical clinic patient. Multi-clinic studies involving residents experienced with SPs should ensure that the SP role and behavior conform to physician expectations and the demographics of the clinic. SP station testing does not accurately reflect physicians' actual clinical behavior and should not be relied on as the primary method of evaluation. The study also suggests that physicians' poor performance in identifying and managing alcohol problems is not entirely due to lack of skill, as they demonstrated greater clinical skills when they became aware that they were being evaluated. Physicians' clinical priorities, sense of responsibility and other attitudinal determinants of their behavior should be addressed when training physicians on the management of alcohol problems.

  20. 2D Quantum Simulation of MOSFET Using the Non Equilibrium Green's Function Method

    Science.gov (United States)

    Svizhenko, Alexel; Anantram, M. P.; Govindan, T. R.; Yan, Jerry (Technical Monitor)

    2000-01-01

    The objectives this viewgraph presentation summarizes include: (1) the development of a quantum mechanical simulator for ultra short channel MOSFET simulation, including theory, physical approximations, and computer code; (2) explore physics that is not accessible by semiclassical methods; (3) benchmarking of semiclassical and classical methods; and (4) study other two-dimensional devices and molecular structure, from discretized Hamiltonian to tight-binding Hamiltonian.

  1. Digital system verification a combined formal methods and simulation framework

    CERN Document Server

    Li, Lun

    2010-01-01

    Integrated circuit capacity follows Moore's law, and chips are commonly produced at the time of this writing with over 70 million gates per device. Ensuring correct functional behavior of such large designs before fabrication poses an extremely challenging problem. Formal verification validates the correctness of the implementation of a design with respect to its specification through mathematical proof techniques. Formal techniques have been emerging as commercialized EDA tools in the past decade. Simulation remains a predominantly used tool to validate a design in industry. After more than 5

  2. Modelling and simulation of diffusive processes methods and applications

    CERN Document Server

    Basu, SK

    2014-01-01

    This book addresses the key issues in the modeling and simulation of diffusive processes from a wide spectrum of different applications across a broad range of disciplines. Features: discusses diffusion and molecular transport in living cells and suspended sediment in open channels; examines the modeling of peristaltic transport of nanofluids, and isotachophoretic separation of ionic samples in microfluidics; reviews thermal characterization of non-homogeneous media and scale-dependent porous dispersion resulting from velocity fluctuations; describes the modeling of nitrogen fate and transport

  3. Discrete vortex method simulations of aerodynamic admittance in bridge aerodynamics

    DEFF Research Database (Denmark)

    Rasmussen, Johannes Tophøj; Hejlesen, Mads Mølholm; Larsen, Allan

    , and to determine aerodynamic forces and the corresponding flutter limit. A simulation of the three-dimensional bridge responseto turbulent wind is carried out by quasi steady theory by modelling the bridge girder as a line like structure [2], applying the aerodynamic load coefficients found from the current version...... of DVMFLOW in a strip wise fashion. Neglecting the aerodynamic admittance, i.e. the correlation of the instantaneous lift force to the turbulent fluctuations in the vertical velocities, leads to higher response to high frequency atmospheric turbulence than would be obtained from wind tunnel tests....

  4. Simulation Methods in the Contact with Impact of Rigid Bodies

    Directory of Open Access Journals (Sweden)

    Cristina Basarabă-Opritescu

    2007-10-01

    Full Text Available The analysis of impacts of elastic bodies is topical and it has many applications, practical and theoretical, too. The elastic character of collision is put in evidence, especially by the velocities of some parts of a particular body, named “ring”. In the presented paper, the situation of elastic collisions is put in evidence by the simulation with the help of the program ANSYS and it refers to the particular case of the ring, with the mechanical characteristics, given in the paper

  5. Degrees of reality: airway anatomy of high-fidelity human patient simulators and airway trainers.

    Science.gov (United States)

    Schebesta, Karl; Hüpfl, Michael; Rössler, Bernhard; Ringl, Helmut; Müller, Michael P; Kimberger, Oliver

    2012-06-01

    Human patient simulators and airway training manikins are widely used to train airway management skills to medical professionals. Furthermore, these patient simulators are employed as standardized "patients" to evaluate airway devices. However, little is known about how realistic these patient simulators and airway-training manikins really are. This trial aimed to evaluate the upper airway anatomy of four high-fidelity patient simulators and two airway trainers in comparison with actual patients by means of radiographic measurements. The volume of the pharyngeal airspace was the primary outcome parameter. Computed tomography scans of 20 adult trauma patients without head or neck injuries were compared with computed tomography scans of four high-fidelity patient simulators and two airway trainers. By using 14 predefined distances, two cross-sectional areas and three volume parameters of the upper airway, the manikins' similarity to a human patient was assessed. The pharyngeal airspace of all manikins differed significantly from the patients' pharyngeal airspace. The HPS Human Patient Simulator (METI®, Sarasota, FL) was the most realistic high-fidelity patient simulator (6/19 [32%] of all parameters were within the 95% CI of human airway measurements). The airway anatomy of four high-fidelity patient simulators and two airway trainers does not reflect the upper airway anatomy of actual patients. This finding may impact airway training and confound comparative airway device studies.

  6. Multiscale closure in the coarse-grid method for the simulation of two-phase flows; Multiskalen-Schliessung in der Grobgitter-Methode zur Simulation zweiphasiger Stroemungen

    Energy Technology Data Exchange (ETDEWEB)

    Noack, Ruediger

    2016-07-01

    In this work a general method for reproduction of two-phase flow fields calculated by generic detailed CFD-simulations on a coarse grid is developed. Numerical models for only few sections of geometry and sets of flow parameters with respectively representative character allow a complete description of the large component considered. Thus a comprehensive three-dimensional CFD-simulation, meeting industrial needs for low computational costs, is generated.

  7. Strengthening student communication through pediatric simulated patient encounters

    Directory of Open Access Journals (Sweden)

    Ryan Whitt

    2014-08-01

    Full Text Available As medical students enter the role of physician, clinical outcomes not only rely on their mastery of clinical knowledge, but also on the effectiveness in which they can communicate with patients and family members. While students typically have numerous opportunities to practice clinical communication with adult patients, such practice in pediatric settings is limited. This study examines if simulated patient (SP encounters strengthen third-year medical students’ communication skills during the pediatrics clerkship. During 2011-2013, three SP encounters (comprising 3 pediatric scenarios were incorporated into a pediatrics clerkship at one United States medical school to give students a safe venue to practice advanced communication with observation and direct feedback. Third-year medical students engaged in the scenarios and received both written and oral feedback from an evaluator observing the encounter. With IRB approval, students’ self-perceived confidence and abilities at performing the advanced communication skills were measured using an eightitem, Likert scale questionnaire administered pre and post the SP encounter. Pre- and post-questionnaires (n = 215; response rate, 96% analyzed using a Wilcoxon-matched pairs signed-rank test demonstrated statistically significant increases in students’ perception of their confidence and abilities regarding their performance (P < 0.05; Bonferroni correction, P < 0.006. There was an increases in student confidence and self-perceived ability in: first, communicating with children and family members of young patients; second, managing confrontational situations involving parents; third, performing a thorough psychosocial history with an adolescent; and fourth, using Evidence Based Medicine to motivate parents.

  8. Simulation Methods for Multiperiodic and Aperiodic Nanostructured Dielectric Waveguides

    DEFF Research Database (Denmark)

    Paulsen, Moritz; Neustock, Lars Thorben; Jahns, Sabrina

    on Rudin-Shapiro, Fibonacci, and Thue-Morse binary sequences. The near-field and far-field properties are calculated employing the finite-element method (FEM), the finite- difference time-domain (FDTD) method as well as a rigorous coupled wave algorithm (RCWA). References [1] S. V. Boriskina, A. Gopinath...

  9. Toward a practical method for adaptive QM/MM simulations

    NARCIS (Netherlands)

    Bulo, R.E.; Ensing, B.; Sikkema, J.; Visscher, L.

    2009-01-01

    We present an accurate adaptive multiscale molecular dynamics method that will enable the detailed study of large molecular systems that mimic experiment. The method treats the reactive regions at the quantum mechanical level and the inactive environment regions at lower levels of accuracy, while at

  10. A non-discrete method for computation of residence time in fluid mechanics simulations.

    Science.gov (United States)

    Esmaily-Moghadam, Mahdi; Hsia, Tain-Yen; Marsden, Alison L

    2013-11-01

    Cardiovascular simulations provide a promising means to predict risk of thrombosis in grafts, devices, and surgical anatomies in adult and pediatric patients. Although the pathways for platelet activation and clot formation are not yet fully understood, recent findings suggest that thrombosis risk is increased in regions of flow recirculation and high residence time (RT). Current approaches for calculating RT are typically based on releasing a finite number of Lagrangian particles into the flow field and calculating RT by tracking their positions. However, special care must be taken to achieve temporal and spatial convergence, often requiring repeated simulations. In this work, we introduce a non-discrete method in which RT is calculated in an Eulerian framework using the advection-diffusion equation. We first present the formulation for calculating residence time in a given region of interest using two alternate definitions. The physical significance and sensitivity of the two measures of RT are discussed and their mathematical relation is established. An extension to a point-wise value is also presented. The methods presented here are then applied in a 2D cavity and two representative clinical scenarios, involving shunt placement for single ventricle heart defects and Kawasaki disease. In the second case study, we explored the relationship between RT and wall shear stress, a parameter of particular importance in cardiovascular disease.

  11. Coupling methods for parallel running RELAPSim codes in nuclear power plant simulation

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yankai; Lin, Meng, E-mail: linmeng@sjtu.edu.cn; Yang, Yanhua

    2016-02-15

    When the plant is modeled detailedly for high precision, it is hard to achieve real-time calculation for one single RELAP5 in a large-scale simulation. To improve the speed and ensure the precision of simulation at the same time, coupling methods for parallel running RELAPSim codes were proposed in this study. Explicit coupling method via coupling boundaries was realized based on a data-exchange and procedure-control environment. Compromise of synchronization frequency was well considered to improve the precision of simulation and guarantee the real-time simulation at the same time. The coupling methods were assessed using both single-phase flow models and two-phase flow models and good agreements were obtained between the splitting–coupling models and the integrated model. The mitigation of SGTR was performed as an integral application of the coupling models. A large-scope NPP simulator was developed adopting six splitting–coupling models of RELAPSim and other simulation codes. The coupling models could improve the speed of simulation significantly and make it possible for real-time calculation. In this paper, the coupling of the models in the engineering simulator is taken as an example to expound the coupling methods, i.e., coupling between parallel running RELAPSim codes, and coupling between RELAPSim code and other types of simulation codes. However, the coupling methods are also referable in other simulator, for example, a simulator employing ATHLETE instead of RELAP5, other logic code instead of SIMULINK. It is believed the coupling method is commonly used for NPP simulator regardless of the specific codes chosen in this paper.

  12. Stochastic linear multistep methods for the simulation of chemical kinetics.

    Science.gov (United States)

    Barrio, Manuel; Burrage, Kevin; Burrage, Pamela

    2015-02-14

    In this paper, we introduce the Stochastic Adams-Bashforth (SAB) and Stochastic Adams-Moulton (SAM) methods as an extension of the τ-leaping framework to past information. Using the Θ-trapezoidal τ-leap method of weak order two as a starting procedure, we show that the k-step SAB method with k ≥ 3 is order three in the mean and correlation, while a predictor-corrector implementation of the SAM method is weak order three in the mean but only order one in the correlation. These convergence results have been derived analytically for linear problems and successfully tested numerically for both linear and non-linear systems. A series of additional examples have been implemented in order to demonstrate the efficacy of this approach.

  13. Reduction Methods for Real-time Simulations in Hybrid Testing

    DEFF Research Database (Denmark)

    Andersen, Sebastian

    2016-01-01

    and complexity of kinematic nonlinear numerical substructures are presented, with special emphasis on the use of basis reduction methods. Three elements that can help to improve the accuracy are presented and illustrated. In kinematic nonlinear systems, various deformation modes are coupled through a nonlinear......Hybrid testing constitutes a cost-effective experimental full scale testing method. The method was introduced in the 1960's by Japanese researchers, as an alternative to conventional full scale testing and small scale material testing, such as shake table tests. The principle of the method...... is to divide a structure into a physical substructure and a numerical substructure, and couple these in a test. If the test is conducted in real-time it is referred to as real time hybrid testing. The hybrid testing concept has developed significantly since its introduction in the 1960', both with respect...

  14. ADAM, a hands-on patient simulator for teaching principles of drug disposition and compartmental pharmacokinetics.

    Science.gov (United States)

    Zuna, Ines; Holt, Andrew

    2017-11-01

    To design, construct and validate a pharmacokinetics simulator that offers students hands-on opportunities to participate in the design, administration and analysis of oral and intravenous dosing regimens. The Alberta Drug Administration Modeller (ADAM) is a mechanical patient in which peristaltic circulation of water through a network of silicone tubing and glass bottles creates a representation of the outcomes of drug absorption, distribution, metabolism and elimination. Changing peristaltic pump rates and volumes in bottles allows values for pharmacokinetic constants to be varied, thereby simulating differences in drug properties and in patient physiologies and pathologies. Following administration of methylene blue dye by oral or intravenous routes, plasma and/or urine samples are collected and drug concentrations are determined spectrophotometrically. The effectiveness of the simulator in enhancing student competence and confidence was assessed in two undergraduate laboratory classes. The simulator effectively models one- and two-compartment drug behaviour in a mathematically-robust and realistic manner. Data allow calculation of numerous pharmacokinetic constants, by traditional graphing methods or with curve-fitting software. Students' competence in solving pharmacokinetic problems involving calculations and graphing improved significantly, while an increase in confidence and understanding was reported. The ADAM is relatively inexpensive and straightforward to construct, and offers a realistic, hands-on pharmacokinetics learning opportunity for students that effectively complements didactic lectures. © 2017 The Authors. British Journal of Clinical Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society.

  15. Validation and Continued Development of Methods for Spheromak Simulation

    Science.gov (United States)

    Benedett, Thomas

    2017-10-01

    The HIT-SI experiment has demonstrated stable sustainment of spheromaks. Determining how the underlying physics extrapolate to larger, higher-temperature regimes is of prime importance in determining the viability of the inductively-driven spheromak. It is thus prudent to develop and validate a computational model that can be used to study current results and study the effect of possible design choices on plasma behavior. An extended MHD model has shown good agreement with experimental data at 14 kHz injector operation. Efforts to extend the existing validation to a range of higher frequencies (36, 53, 68 kHz) using the PSI-Tet 3D extended MHD code will be presented, along with simulations of potential combinations of flux conserver features and helicity injector configurations and their impact on current drive performance, density control, and temperature for future SIHI experiments. Work supported by USDoE.

  16. Phase portrait methods for verifying fluid dynamic simulations

    Energy Technology Data Exchange (ETDEWEB)

    Stewart, H.B.

    1989-01-01

    As computing resources become more powerful and accessible, engineers more frequently face the difficult and challenging engineering problem of accurately simulating nonlinear dynamic phenomena. Although mathematical models are usually available, in the form of initial value problems for differential equations, the behavior of the solutions of nonlinear models is often poorly understood. A notable example is fluid dynamics: while the Navier-Stokes equations are believed to correctly describe turbulent flow, no exact mathematical solution of these equations in the turbulent regime is known. Differential equations can of course be solved numerically, but how are we to assess numerical solutions of complex phenomena without some understanding of the mathematical problem and its solutions to guide us

  17. Method of Modeling and Simulation of Shaped External Occulters

    Science.gov (United States)

    Lyon, Richard G. (Inventor); Clampin, Mark (Inventor); Petrone, Peter, III (Inventor)

    2016-01-01

    The present invention relates to modeling an external occulter including: providing at least one processor executing program code to implement a simulation system, the program code including: providing an external occulter having a plurality of petals, the occulter being coupled to a telescope; and propagating light from the occulter to a telescope aperture of the telescope by scalar Fresnel propagation, by: obtaining an incident field strength at a predetermined wavelength at an occulter surface; obtaining a field propagation from the occulter to the telescope aperture using a Fresnel integral; modeling a celestial object at differing field angles by shifting a location of a shadow cast by the occulter on the telescope aperture; calculating an intensity of the occulter shadow on the telescope aperture; and applying a telescope aperture mask to a field of the occulter shadow, and propagating the light to a focal plane of the telescope via FFT techniques.

  18. Action potential simulation (APS) in patients with fibromyalgia syndrome (FMS): a controlled single subject experimental design.

    Science.gov (United States)

    Fengler, R K B; Jacobs, J W G; Bac, M; van Wijck, A J M; van Meeteren, N L U

    2007-03-01

    Action potential simulation (APS) is becoming a popular method of pain reduction. Nevertheless, little is known about the efficacy of this relatively new treatment. The aim of this study was to investigate whether APS helps to reduce pain, improves patients' perception of daily functioning and social participation in patients with fibromyalgia syndrome (FMS). Ten patients with FMS according to the American College of Rheumatology (ACR) criteria entered this double blind crossover single-case study. In a period of 20 weeks, the patients underwent two treatment periods of 4 weeks, one with verum and one with placebo, at random, in a double blind fashion. Outcome measures were evaluated on a weekly basis. Primary outcome measure was pain measured with the Fibromyalgia Impact Questionnaire (FIQ) questions 4 and 5, the number of tender points and the total tender point pain intensity score. Both visual inspection and statistical analysis were done to analyse the data from this single-subject design. Performing visual inspection and statistical analysis, no positive results of the APS treatment were found in this study. Remarkable is the fact that placebo APS had significantly better results than verum APS. In this single-case study with ten patients (all female), APS was not a helpful method to reduce pain, to improve patients' perception of daily functioning and social participation in patients with FMS.

  19. Simulation of 3D tumor cell growth using nonlinear finite element method.

    Science.gov (United States)

    Dong, Shoubing; Yan, Yannan; Tang, Liqun; Meng, Junping; Jiang, Yi

    2016-01-01

    We propose a novel parallel computing framework for a nonlinear finite element method (FEM)-based cell model and apply it to simulate avascular tumor growth. We derive computation formulas to simplify the simulation and design the basic algorithms. With the increment of the proliferation generations of tumor cells, the FEM elements may become larger and more distorted. Then, we describe a remesh and refinement processing of the distorted or over large finite elements and the parallel implementation based on Message Passing Interface to improve the accuracy and efficiency of the simulation. We demonstrate the feasibility and effectiveness of the FEM model and the parallelization methods in simulations of early tumor growth.

  20. Modeling and Simulation of DC Power Electronics Systems Using Harmonic State Space (HSS) Method

    DEFF Research Database (Denmark)

    Kwon, Jun Bum; Wang, Xiongfei; Bak, Claus Leth

    2015-01-01

    based on the state-space averaging and generalized averaging, these also have limitations to show the same results as with the non-linear time domain simulations. This paper presents a modeling and simulation method for a large dc power electronic system by using Harmonic State Space (HSS) modeling....... Through this method, the required computation time and CPU memory for large dc power electronics systems can be reduced. Besides, the achieved results show the same results as with the non-linear time domain simulation, but with the faster simulation time which is beneficial in a large network....

  1. Frequency Domain Modeling and Simulation of DC Power Electronic Systems Using Harmonic State Space Method

    DEFF Research Database (Denmark)

    Kwon, Jun Bum; Wang, Xiongfei; Blaabjerg, Frede

    2017-01-01

    . Through this method, the required computation time and CPU memory can be reduced, where this faster simulation can be an advantage of a large network simulation. Besides, the achieved results show the same results as the non-linear time-domain simulation. Furthermore, the HSS modeling can describe how...... with different switching frequency or harmonics from ac-dc converters makes that harmonics and frequency coupling are both problems of ac system and challenges of dc system. This paper presents a modeling and simulation method for a large dc power electronic system by using Harmonic State Space (HSS) modeling...

  2. Hybrid statistics-simulations based method for atom-counting from ADF STEM images

    Energy Technology Data Exchange (ETDEWEB)

    De wael, Annelies, E-mail: annelies.dewael@uantwerpen.be [Electron Microscopy for Materials Science (EMAT), University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp (Belgium); De Backer, Annick [Electron Microscopy for Materials Science (EMAT), University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp (Belgium); Jones, Lewys; Nellist, Peter D. [Department of Materials, University of Oxford, Parks Road, OX1 3PH Oxford (United Kingdom); Van Aert, Sandra, E-mail: sandra.vanaert@uantwerpen.be [Electron Microscopy for Materials Science (EMAT), University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp (Belgium)

    2017-06-15

    A hybrid statistics-simulations based method for atom-counting from annular dark field scanning transmission electron microscopy (ADF STEM) images of monotype crystalline nanostructures is presented. Different atom-counting methods already exist for model-like systems. However, the increasing relevance of radiation damage in the study of nanostructures demands a method that allows atom-counting from low dose images with a low signal-to-noise ratio. Therefore, the hybrid method directly includes prior knowledge from image simulations into the existing statistics-based method for atom-counting, and accounts in this manner for possible discrepancies between actual and simulated experimental conditions. It is shown by means of simulations and experiments that this hybrid method outperforms the statistics-based method, especially for low electron doses and small nanoparticles. The analysis of a simulated low dose image of a small nanoparticle suggests that this method allows for far more reliable quantitative analysis of beam-sensitive materials. - Highlights: • A hybrid method for atom-counting from ADF STEM images is introduced. • Image simulations are incorporated into a statistical framework in a reliable manner. • Limits of the existing methods for atom-counting are far exceeded. • Reliable counting results from an experimental low dose image are obtained. • Progress towards reliable quantitative analysis of beam-sensitive materials is made.

  3. Virtual patient simulation: Promotion of clinical reasoning abilities of medical students

    Directory of Open Access Journals (Sweden)

    Rokhsareh Aghili

    2012-12-01

    Full Text Available Objectives: Virtual patient simulation (VPS is used in the education of health care professionals. This method brings an opportunity for the learner to examine necessary diagnostic and therapeutic skills. The aim of this study was to assess the efficacy of VPS on clinical reasoning abilities of medical students and to evaluate their attitude towards VPS in clinical endocrinology course in a teacher centered educational environment.Methods: Fifty-one medical students in their 6th academic year were simply randomized in two groups, the simulation and the control. The students in the simulation group were provided by an application which presented them virtual case scenarios on diagnosis and management of thyroid nodules and osteomalacia. All the students sat for a diagnostic test at the beginning and at the end of the course. The test comprised a series of essay questions matched for their academic level and closely related to the case scenarios. They were also asked to complete a questionnaire to assess their attitude towards the application.Results: Participants in both groups did not have any statistical differences in scientific background in basic sciences (P=0.672 and prior clinical examinations (P=0.376. At completion of the course the mean score of the students in the simulation group improved significantly compared to the students in the control group by 3.5 vs. 1.0 points (P=0.001. The students found the application worthful and showed a positive attitude towards it.Conclusions: Virtual patient simulation improved clinical reasoning abilities of medical students in the context of a traditional teaching/learning environment.

  4. An efficient hybrid explicit/implicit solvent method for biomolecular simulations.

    Science.gov (United States)

    Lee, Michael S; Salsbury, Freddie R; Olson, Mark A

    2004-12-01

    We present a new hybrid explicit/implicit solvent method for dynamics simulations of macromolecular systems. The method models explicitly the hydration of the solute by either a layer or sphere of water molecules, and the generalized Born (GB) theory is used to treat the bulk continuum solvent outside the explicit simulation volume. To reduce the computational cost, we implemented a multigrid method for evaluating the pairwise electrostatic and GB terms. It is shown that for typical ion and protein simulations our method achieves similar equilibrium and dynamical observables as the conventional particle mesh Ewald (PME) method. Simulation timings are reported, which indicate that the hybrid method is much faster than PME, primarily due to a significant reduction in the number of explicit water molecules required to model hydration effects. (c) 2004 Wiley Periodicals, Inc.

  5. Applying dynamic simulation modeling methods in health care delivery research-the SIMULATE checklist: report of the ISPOR simulation modeling emerging good practices task force.

    Science.gov (United States)

    Marshall, Deborah A; Burgos-Liz, Lina; IJzerman, Maarten J; Osgood, Nathaniel D; Padula, William V; Higashi, Mitchell K; Wong, Peter K; Pasupathy, Kalyan S; Crown, William

    2015-01-01

    Health care delivery systems are inherently complex, consisting of multiple tiers of interdependent subsystems and processes that are adaptive to changes in the environment and behave in a nonlinear fashion. Traditional health technology assessment and modeling methods often neglect the wider health system impacts that can be critical for achieving desired health system goals and are often of limited usefulness when applied to complex health systems. Researchers and health care decision makers can either underestimate or fail to consider the interactions among the people, processes, technology, and facility designs. Health care delivery system interventions need to incorporate the dynamics and complexities of the health care system context in which the intervention is delivered. This report provides an overview of common dynamic simulation modeling methods and examples of health care system interventions in which such methods could be useful. Three dynamic simulation modeling methods are presented to evaluate system interventions for health care delivery: system dynamics, discrete event simulation, and agent-based modeling. In contrast to conventional evaluations, a dynamic systems approach incorporates the complexity of the system and anticipates the upstream and downstream consequences of changes in complex health care delivery systems. This report assists researchers and decision makers in deciding whether these simulation methods are appropriate to address specific health system problems through an eight-point checklist referred to as the SIMULATE (System, Interactions, Multilevel, Understanding, Loops, Agents, Time, Emergence) tool. It is a primer for researchers and decision makers working in health care delivery and implementation sciences who face complex challenges in delivering effective and efficient care that can be addressed with system interventions. On reviewing this report, the readers should be able to identify whether these simulation modeling

  6. Impact of Standardized Simulated Patients on First-Year Pharmacy Students' Knowledge Retention of Insulin Injection Technique and Counseling Skills.

    Science.gov (United States)

    Bowers, Riley; Tunney, Robert; Kelly, Kim; Mills, Beth; Trotta, Katie; Wheeless, C Neil; Drew, Richard

    2017-08-01

    Objective. To compare pre- and post-intervention test scores assessing insulin injection technique and counseling skills among P1 students with (intervention) or without (control) simulated patients, and to compare counseling checklist and knowledge retention test scores between groups. Methods. This study utilized cluster randomization. In addition to traditional instruction, the intervention group counseled a simulated patient on the use of insulin using the teach-back method. Test score changes from baseline were analyzed via two-sample t-test. Results. The intervention group exhibited a significantly greater increase in knowledge test scores from baseline compared to the control group. Similar changes were seen in post-instruction counseling checklist scores and knowledge retention test scores from baseline. Conclusion. Simulated patient interactions, when added to traditional coursework within a P1 skills lab, improve student counseling aptitude and knowledge retention scores.

  7. Impaired driving simulation in patients with Periodic Limb Movement Disorder and patients with Obstructive Sleep Apnea Syndrome

    NARCIS (Netherlands)

    Gieteling, Esther W.; Bakker, Marije S.; Hoekema, Aarnoud; Maurits, Natasha M.; Brouwer, Wiebo H.; van der Hoeven, Johannes H.

    Background: Excessive daytime sleepiness (EDS) is considered to be responsible for increased collision rate and impaired driving simulator performance in Obstructive Sleep Apnea Syndrome (OSAS) patients. Periodic Limb Movement Disorder (PLMD) patients also frequently report EDS and may also have

  8. Application of Conjugate Gradient methods to tidal simulation

    Science.gov (United States)

    Barragy, E.; Carey, G.F.; Walters, R.A.

    1993-01-01

    A harmonic decomposition technique is applied to the shallow water equations to yield a complex, nonsymmetric, nonlinear, Helmholtz type problem for the sea surface and an accompanying complex, nonlinear diagonal problem for the velocities. The equation for the sea surface is linearized using successive approximation and then discretized with linear, triangular finite elements. The study focuses on applying iterative methods to solve the resulting complex linear systems. The comparative evaluation includes both standard iterative methods for the real subsystems and complex versions of the well known Bi-Conjugate Gradient and Bi-Conjugate Gradient Squared methods. Several Incomplete LU type preconditioners are discussed, and the effects of node ordering, rejection strategy, domain geometry and Coriolis parameter (affecting asymmetry) are investigated. Implementation details for the complex case are discussed. Performance studies are presented and comparisons made with a frontal solver. ?? 1993.

  9. Patient-specific blood flow simulation to improve intracranial aneurysm diagnosis

    Science.gov (United States)

    Fenz, Wolfgang; Dirnberger, Johannes

    2011-03-01

    We present a novel simulation system of blood flow through intracranial aneurysms including the interaction between blood lumen and vessel tissue. It provides the means to estimate rupture risks by calculating the distribution of pressure and shear stresses in the aneurysm, in order to support the planning of clinical interventions. So far, this has only been possible with commercial simulation packages originally targeted at industrial applications, whereas our implementation focuses on the intuitive integration into clinical workflow. Due to the time-critical nature of the application, we exploit most efficient state-of-the-art numerical methods and technologies together with high performance computing infrastructures (Austrian Grid). Our system builds a three-dimensional virtual replica of the patient's cerebrovascular system from X-ray angiography, CT or MR images. The physician can then select a region of interest which is automatically transformed into a tetrahedral mesh. The differential equations for the blood flow and the wall elasticity are discretized via the finite element method (FEM), and the resulting linear equation systems are handled by an algebraic multigrid (AMG) solver. The wall displacement caused by the blood pressure is calculated using an iterative fluid-structure interaction (FSI) algorithm, and the fluid mesh is deformed accordingly. First simulation results on measured patient geometries show good medical relevance for diagnostic decision support.

  10. Simple method for any planar wiggler field simulation

    Directory of Open Access Journals (Sweden)

    M. N. Smolyakov

    2001-04-01

    Full Text Available This paper deals with a nonstandard method for calculating the magnetic field of planar wigglers and undulators consisting of pure permanent magnets. This method of calculation is based on certain properties of the Fourier transform. It allows the analytical expression of the Fourier transform for the planar magnetic fields through the wiggler's geometry and magnetization of its blocks. The upper theoretical limit for the amplitude of the magnetic field is derived and matched with the field amplitude of planar wigglers with standard designs. The property of universality for planar wigglers is also taken into consideration as it may greatly simplify the analysis of magnetic fields for wigglers with different designs.

  11. Simulation of Outer Rotor Permanent Magnet Brushless DC Motor Using Finite Element Method for Torque Improvement

    Directory of Open Access Journals (Sweden)

    Uma Devi Kumaravelu

    2012-01-01

    Full Text Available A method of simulation and modeling outer rotor permanent magnet brushless DC (ORPMBLDC motor under dynamic conditions using finite element method by FEMM 4.2 software package is presented. In the proposed simulation, the torque developed at various positions of the rotor, under a complete cycle of excitation of the stator, is analysed. A novel method of sinusoidal excitation is proposed to enhance the overall torque development of ORPMBLDC motor.

  12. A Fast Finite-Difference Time Domain Simulation Method for the Source-Stirring Reverberation Chamber

    OpenAIRE

    Wenxing Li; Chongyi Yue; Atef Elsherbeni

    2017-01-01

    Numerical analysis methods are often employed to improve the efficiency of the design and application of the source-stirring reverberation chamber. However, the state of equilibrium of the field inside the chamber is hard to reach. In this paper, we present a fast simulation method, which is able to significantly decrease the simulation time of the source-stirring reverberation chamber. The mathematical model of this method is given in detail and home-made FDTD code is employed to conduct the...

  13. Simulation of Outer Rotor Permanent Magnet Brushless DC Motor Using Finite Element Method for Torque Improvement

    OpenAIRE

    Uma Devi Kumaravelu; Sanavullah Mohamed Yakub

    2012-01-01

    A method of simulation and modeling outer rotor permanent magnet brushless DC (ORPMBLDC) motor under dynamic conditions using finite element method by FEMM 4.2 software package is presented. In the proposed simulation, the torque developed at various positions of the rotor, under a complete cycle of excitation of the stator, is analysed. A novel method of sinusoidal excitation is proposed to enhance the overall torque development of ORPMBLDC motor.

  14. Simulation of marine controlled source electromagnetic measurements using a parallel fourier hp-finite element method

    OpenAIRE

    Pardo D.; Nam M.J.; Torres-Verdín C.; Hoversten M.G.; Garay Iñ.

    2011-01-01

    We introduce a new numerical method to simulate geophysical marine controlled source electromagnetic (CSEM) measurements for the case of 2D structures and finite 3D sources of electromagnetic (EM) excitation. The method of solution is based on a spatial discretization that combines a 1D Fourier transform with a 2D self-adaptive, goal-oriented, hp-Finite element method. It enables fast and accurate simulations for a variety of important, challenging and practical cases of marine CSEM acquisiti...

  15. Inhalation of tobramycin using simulated cystic fibrosis patient profiles.

    Science.gov (United States)

    Haynes, Alfred; Geller, David; Weers, Jeffry; Ament, Brian; Pavkov, Richard; Malcolmson, Richard; Debonnett, Laurie; Mastoridis, Paul; Yadao, Anthony; Heuerding, Silvia

    2016-11-01

    TOBI(®) Podhaler™ is a capsule-based drug-device combination (tobramycin inhalation powder [TIP] 28 mg capsules via unit-dose dry powder T-326 Inhaler [Podhaler™]) developed for treatment of Pseudomonas aeruginosa infection in cystic fibrosis (CF). We explored how inspiratory flow profiles and mouth-throat geometries affect drug delivery with the T-326 Inhaler. Inspiratory flow profiles were recorded from 38 subjects aged 6-71 who had CF and varying degrees of lung function impairment. Ten of the inspiratory flow profiles were simulated in the laboratory using a custom breath simulator to determine delivered dose (DD) from the T-326 Inhaler. In vitro total lung dose (TLDin vitro ) was measured using four anatomical throat models, ranging from a child to a large adult. Aerosol performance was assessed across a range of inspiratory flow profiles. Mean DD ranged from 88.8% to 97.0% of declared capsule content. TLDin vitro ranged from 54.8% to 72.4% of capsule content between the flow profile/throat options tested, and the mean TLDin vitro across the range of flow profiles and anatomical throats tested was 63 ± 5%. Our findings indicate that the T-326 Inhaler provides reliable drug delivery at flow rates likely to be achieved by a broad spectrum of patients with CF. Importantly, forceful inhalation was not required to achieve a robust TLDin vitro . Pediatr Pulmonol. 2016;51:1159-1167. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  16. Simple Method to Estimate Mean Heart Dose From Hodgkin Lymphoma Radiation Therapy According to Simulation X-Rays

    Energy Technology Data Exchange (ETDEWEB)

    Nimwegen, Frederika A. van [Department of Psychosocial Research, Epidemiology, and Biostatistics, The Netherlands Cancer Institute, Amsterdam (Netherlands); Cutter, David J. [Clinical Trial Service Unit, University of Oxford, Oxford (United Kingdom); Oxford Cancer Centre, Oxford University Hospitals NHS Trust, Oxford (United Kingdom); Schaapveld, Michael [Department of Psychosocial Research, Epidemiology, and Biostatistics, The Netherlands Cancer Institute, Amsterdam (Netherlands); Rutten, Annemarieke [Department of Radiology, The Netherlands Cancer Institute, Amsterdam (Netherlands); Kooijman, Karen [Department of Psychosocial Research, Epidemiology, and Biostatistics, The Netherlands Cancer Institute, Amsterdam (Netherlands); Krol, Augustinus D.G. [Department of Radiation Oncology, Leiden University Medical Center, Leiden (Netherlands); Janus, Cécile P.M. [Department of Radiation Oncology, Erasmus MC Cancer Center, Rotterdam (Netherlands); Darby, Sarah C. [Clinical Trial Service Unit, University of Oxford, Oxford (United Kingdom); Leeuwen, Flora E. van [Department of Psychosocial Research, Epidemiology, and Biostatistics, The Netherlands Cancer Institute, Amsterdam (Netherlands); Aleman, Berthe M.P., E-mail: b.aleman@nki.nl [Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam (Netherlands)

    2015-05-01

    Purpose: To describe a new method to estimate the mean heart dose for Hodgkin lymphoma patients treated several decades ago, using delineation of the heart on radiation therapy simulation X-rays. Mean heart dose is an important predictor for late cardiovascular complications after Hodgkin lymphoma (HL) treatment. For patients treated before the era of computed tomography (CT)-based radiotherapy planning, retrospective estimation of radiation dose to the heart can be labor intensive. Methods and Materials: Patients for whom cardiac radiation doses had previously been estimated by reconstruction of individual treatments on representative CT data sets were selected at random from a case–control study of 5-year Hodgkin lymphoma survivors (n=289). For 42 patients, cardiac contours were outlined on each patient's simulation X-ray by 4 different raters, and the mean heart dose was estimated as the percentage of the cardiac contour within the radiation field multiplied by the prescribed mediastinal dose and divided by a correction factor obtained by comparison with individual CT-based dosimetry. Results: According to the simulation X-ray method, the medians of the mean heart doses obtained from the cardiac contours outlined by the 4 raters were 30 Gy, 30 Gy, 31 Gy, and 31 Gy, respectively, following prescribed mediastinal doses of 25-42 Gy. The absolute-agreement intraclass correlation coefficient was 0.93 (95% confidence interval 0.85-0.97), indicating excellent agreement. Mean heart dose was 30.4 Gy with the simulation X-ray method, versus 30.2 Gy with the representative CT-based dosimetry, and the between-method absolute-agreement intraclass correlation coefficient was 0.87 (95% confidence interval 0.80-0.95), indicating good agreement between the two methods. Conclusion: Estimating mean heart dose from radiation therapy simulation X-rays is reproducible and fast, takes individual anatomy into account, and yields results comparable to the labor

  17. Development of new deactivation method for simulation of fluid ...

    Indian Academy of Sciences (India)

    processing unit in the petroleum industry for converting gas oil streams into high octane gasoline, cycle oils, and .... 4.0. 292. 72. 24.66. - where Z/M= ratio of zeolite to matrix. MM= Mitchell method equilibrium catalyst. *Numbers in the bracket indicate percent E-Cat metals. TPR unit. In an experiment, 250 mg of the catalyst.

  18. A Simulator to Enhance Teaching and Learning of Mining Methods ...

    African Journals Online (AJOL)

    Audio visual education that incorporates devices and materials which involve sight, sound, or both has become a sine qua non in recent times in the teaching and learning process. An automated physical model of mining methods aided with video instructions was designed and constructed by harnessing locally available ...

  19. Modified enthalpy method for the simulation of melting and ...

    Indian Academy of Sciences (India)

    face obtained is compared satisfactorily with the experimental results available in literature. Keywords. Melting; enthalpy method; wavy interface; mushy zone constant. 1. Introduction. The study of melting and solidification offers insights in the design of casting, welding, latent thermal energy storage systems, etc., and in the ...

  20. Partial Variance of Increments Method in Solar Wind Observations and Plasma Simulations

    Science.gov (United States)

    Greco, A.; Matthaeus, W. H.; Perri, S.; Osman, K. T.; Servidio, S.; Wan, M.; Dmitruk, P.

    2018-02-01

    The method called "PVI" (Partial Variance of Increments) has been increasingly used in analysis of spacecraft and numerical simulation data since its inception in 2008. The purpose of the method is to study the kinematics and formation of coherent structures in space plasmas, a topic that has gained considerable attention, leading the development of identification methods, observations, and associated theoretical research based on numerical simulations. This review paper will summarize key features of the method and provide a synopsis of the main results obtained by various groups using the method. This will enable new users or those considering methods of this type to find details and background collected in one place.

  1. Mathematical modeling and simulation methods in energy systems

    Energy Technology Data Exchange (ETDEWEB)

    Bahn, O. [Montreal Univ., PQ (Canada). Ecole des Hautes Etudes Commerciales; Haurie, A. [Montreal Univ., PQ (Canada). Groupe d' etudes et de recherche en analyse des decisions]|[Geneva Univ., (Switzerland); Zachary, D.S. [American Univ. of Sharjah (United Arab Emirates). Dept. of Physics

    2004-05-01

    This study reviewed a modeling approach that evaluates the interactions between the economy of a region, its energy production/consumption system and the environmental impacts of these activities. Various linear programming models have been used to examine how an economy can adapt to abrupt changes in crude oil supply as a primary energy source. Although the models capture the complex interactions between technologies, energy options, economic development and social acceptance of energy policies, they should be modified to clarify the fact that energy demand is a derived demand that is related to technology choices. The models should also clarify that energy is a fundamental resource for the economy. As such, energy demand is influenced by macro-economic adjustments occurring in other economic sectors. This paper presents a first account of the general structure and potential use of mathematical and simulation models of energy systems. A first taxonomy of energy-economy-environment (E3) models was provided along with their main modeling approach. An alternative classification was proposed and technology ranking was discussed along with some issues in energy modeling. 16 refs., 1 tab., 2 figs.

  2. Bayesian statistic methods and theri application in probabilistic simulation models

    Directory of Open Access Journals (Sweden)

    Orietta Zaniolo

    2006-03-01

    Full Text Available Significant advances in the management of hypercholesterolemia have been made possible by the development of statins, 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA reductase inhibitors. More recently, statins have demonstrated benefit in primary and secondary prevention of cardiovascular disease also in patients without hypercholesterolemia. Therefore statins help to reduce the impact of cardiovascular disease on morbility, mortality and social costs. Statins inhibit HMG-CoA reductase competitively, reduce LDL levels more than other cholesterol-lowering drugs, and lower triglyceride levels in hypertriglyceridemic patients. Prescribing statins as first line therapy in management of hypercholesterolemia as a part of a more comprehensive prevention program of cardiovascular disease is widely recommended by international guidelines (e.g. National Cholesterol Education Program - NCEP - Adult Treatment Panel - ATP- III reports. Currently in Italy there are five available statins: atorvastatin, fluvastatin, pravastatin, rosuvastatin and simvastatin; each of them presents some differences in physical and chemical characteristics (solubility, pharmacokinetics (absorption, proteic binding, metabolism and excretion and pharmacodinamics (pleiotropic effects. Compared to other statins, fluvastatin extended-release (RP 80 mg provides an equal efficacy in lowering total cholesterol and low-density lipoprotein cholesterol (LDL-C, with an important action on triglyceride (TG levels and superior increases in HDL-C levels, reducing the incidence of major adverse cardiac events (MACE. Aim of this study is to outline an updated therapeutic and pharmacoeconomic profile of fluvastatin, particularly regarding extended-release (RP 80 mg formulation.

  3. Simulation As a Method To Support Complex Organizational Transformations in Healthcare

    OpenAIRE

    Rothengatter, D.C.F.; Katsma, Christiaan; Van Hillegersberg, Jos

    2010-01-01

    In this paper we study the application of simulation as a method to support information system and process design in complex organizational transitions. We apply a combined use of a collaborative workshop approach with the use of a detailed and accurate graphical simulation model in a hospital that is in a major transition. The simulation represents the future situation of the hospital and enables the healthcare professionals to analyze and reflect on processes, planning, staffing and collabo...

  4. SPACE CHARGE SIMULATION METHODS INCORPORATED IN SOME MULTI - PARTICLE TRACKING CODES AND THEIR RESULTS COMPARISON.

    Energy Technology Data Exchange (ETDEWEB)

    BEEBE - WANG,J.; LUCCIO,A.U.; D IMPERIO,N.; MACHIDA,S.

    2002-06-03

    Space charge in high intensity beams is an important issue in accelerator physics. Due to the complicity of the problems, the most effective way of investigating its effect is by computer simulations. In the resent years, many space charge simulation methods have been developed and incorporated in various 2D or 3D multi-particle-tracking codes. It has becoming necessary to benchmark these methods against each other, and against experimental results. As a part of global effort, we present our initial comparison of the space charge methods incorporated in simulation codes ORBIT++, ORBIT and SIMPSONS. In this paper, the methods included in these codes are overviewed. The simulation results are presented and compared. Finally, from this study, the advantages and disadvantages of each method are discussed.

  5. [Application of power band graph method to the modeling and simulation of cardiovascular system].

    Science.gov (United States)

    Feng, Y; Feng, Y; Tian, S; Ling, H; Chen, S

    1999-09-01

    This paper presents a computer simulation model of the cardiovascular circulation system, which describes the blood flow dynamic law in the cardiovascular system by the state equation. The model can be used in physiological study and computer-aided medical education. In this paper, the Power Band Graph (PBG) modeling method is used to realize modeling of the human circulation system and conduct a simulation study on a simplified physiological system model. The results demonstrate that the PBG method, as an understandable and unity modeling method, is quite effective and practicable and can be used widely in the field of physiological system simulation.

  6. Methods and Simulations of Muon Tomography and Reconstruction

    Science.gov (United States)

    Schreiner, Henry Fredrick, III

    This dissertation investigates imaging with cosmic ray muons using scintillator-based portable particle detectors, and covers a variety of the elements required for the detectors to operate and take data, from the detector internal communications and software algorithms to a measurement to allow accurate predictions of the attenuation of physical targets. A discussion of the tracking process for the three layer helical design developed at UT Austin is presented, with details of the data acquisition system, and the highly efficient data format. Upgrades to this system provide a stable system for taking images in harsh or inaccessible environments, such as in a remote jungle in Belize. A Geant4 Monte Carlo simulation was used to develop our understanding of the efficiency of the system, as well as to make predictions for a variety of different targets. The projection process is discussed, with a high-speed algorithm for sweeping a plane through data in near real time, to be used in applications requiring a search through space for target discovery. Several other projections and a foundation of high fidelity 3D reconstructions are covered. A variable binning scheme for rapidly varying statistics over portions of an image plane is also presented and used. A discrepancy in our predictions and the observed attenuation through smaller targets is shown, and it is resolved with a new measurement of low energy spectrum, using a specially designed enclosure to make a series of measurements underwater. This provides a better basis for understanding the images of small amounts of materials, such as for thin cover materials.

  7. A Workflow for Patient-Individualized Virtual Angiogram Generation Based on CFD Simulation

    Directory of Open Access Journals (Sweden)

    Jürgen Endres

    2012-01-01

    Full Text Available Increasing interest is drawn on hemodynamic parameters for classifying the risk of rupture as well as treatment planning of cerebral aneurysms. A proposed method to obtain quantities such as wall shear stress, pressure, and blood flow velocity is to numerically simulate the blood flow using computational fluid dynamics (CFD methods. For the validation of those calculated quantities, virtually generated angiograms, based on the CFD results, are increasingly used for a subsequent comparison with real, acquired angiograms. For the generation of virtual angiograms, several patient-specific parameters have to be incorporated to obtain virtual angiograms which match the acquired angiograms as best as possible. For this purpose, a workflow is presented and demonstrated involving multiple phantom and patient cases.

  8. Simulation method for interference fringe patterns in measuring gear tooth flanks by laser interferometry.

    Science.gov (United States)

    Fang, Suping; Wang, Leijie; Komori, Masaharu; Kubo, Aizoh

    2010-11-20

    We present a ray-tracing-based method for simulation of interference fringe patterns (IFPs) for measuring gear tooth flanks with a two-path interferometer. This simulation method involves two steps. In the first step, the profile of an IFP is achieved by means of ray tracing within the object path of the interferometer. In the second step, the profile of an IFP is filled with interference fringes, according to a set of functions from an optical path length to a fringe gray level. To examine the correctness of this simulation method, simulations are performed for two spur involute gears, and the simulated IFPs are verified by experiments using the actual two-path interferometer built on an optical platform.

  9. The Monte Carlo Simulation Method for System Reliability and Risk Analysis

    CERN Document Server

    Zio, Enrico

    2013-01-01

    Monte Carlo simulation is one of the best tools for performing realistic analysis of complex systems as it allows most of the limiting assumptions on system behavior to be relaxed. The Monte Carlo Simulation Method for System Reliability and Risk Analysis comprehensively illustrates the Monte Carlo simulation method and its application to reliability and system engineering. Readers are given a sound understanding of the fundamentals of Monte Carlo sampling and simulation and its application for realistic system modeling.   Whilst many of the topics rely on a high-level understanding of calculus, probability and statistics, simple academic examples will be provided in support to the explanation of the theoretical foundations to facilitate comprehension of the subject matter. Case studies will be introduced to provide the practical value of the most advanced techniques.   This detailed approach makes The Monte Carlo Simulation Method for System Reliability and Risk Analysis a key reference for senior undergra...

  10. Orthotropic node-separation finite element method for composite laminate in hypervelocity impact simulation

    Science.gov (United States)

    Zhang, Xiaotian; Liu, Tao; Qiu, Xinming

    2017-11-01

    This paper reports a finite element modeling approach to simulate the hypervelocity impact (HVI) response of composite laminate. Node-separation finite element (NSFE) method based on scalar-element-fracture technique for isotropic material in HVI simulation has been presented in the previous study. To extend NSFE to composite materials, an orthotropic node-separation finite element (ONSFE) method is developed. This approach employs an orthotropic continuum material model and a corresponding orthotropic-element-fracture technique to represent the HVI behavior/damage of composite laminate. A series of HVI simulations are conducted and the developed ONSFE method is validated by comparing with the experimental data. The simulation results show that ONSFE can successfully capture the HVI phenomena of composite laminate, such as the orthotropic property, nonlinear shock response, perforation, fiber breakage and delamination. Finally, a HVI event of Whipple shield is simulated and the computational capability of ONSFE for predicting the damage state of the composite bumper is further evaluated.

  11. Family Medicine Residents' Performance with Detected Versus Undetected Simulated Patients Posing as Problem Drinkers

    Directory of Open Access Journals (Sweden)

    Mark B. Sobell, PhD

    2004-01-01

    Full Text Available Background: Simulated patients are commonly used to evaluate medical trainees. Unannounced simulated patients provide an accurate measure of physician performance. Purpose: To determine the effects of detection of SPs on physician performance, and identify factors leading to detection. Methods: Fixty-six family medicine residents were each visited by two unannounced simulated patients presenting with alcohol-induced hypertension or insomnia. Residents were then surveyed on their detection of SPs. Results: SPs were detected on 45 out of 104 visits. Inner city clinics had higher detection rates than middle class clinics. Residents’ checklist and global rating scores were substantially higher on detected than undetected visits, for both between-subject and within-subject comparisons. The most common reasons for detection concerned SP demographics and behaviour; the SP “did not act like a drinker” and was of a different social class than the typical clinic patient. Conclusions: Multi-clinic studies involving residents experienced with SPs should ensure that the SP role and behavior conform to physician expectations and the demographics of the clinic. SP station testing does not accurately reflect physicians’ actual clinical behavior and should not be relied on as the primary method of evaluation. The study also suggests that physicians’ poor performance in identifying and managing alcohol problems is not entirely due to lack of skill, as they demonstrated greater clinical skills when they became aware that they were being evaluated. Physicians’ clinical priorities, sense of responsibility and other attitudinal determinants of their behavior should be addressed when training physicians on the management of alcohol problems.

  12. Using the Simulated Patient Methodology to Assess Paracetamol-Related Counselling for Headache

    Science.gov (United States)

    Horvat, Nejc; Koder, Marko; Kos, Mitja

    2012-01-01

    Objectives Firstly, to assess paracetamol-related counselling. Secondly, to evaluate the patient’s approach as a determinant of counselling and to test the acceptability of the simulated patient method in Slovenian pharmacies. Methods The simulated patient methodology was used in 17 community pharmacies. Three scenarios related to self-medication for headaches were developed and used in all participating pharmacies. Two scenarios were direct product requests: scenario 1: a patient with an uncomplicated short-term headache; scenario 2: a patient with a severe, long-duration headache who takes paracetamol for too long and concurrently drinks alcohol. Scenario 3 was a symptom-based request: a patient asking for medicine for a headache. Pharmacy visits were audio recorded and scored according to predetermined criteria arranged in two categories: counselling content and manner of counselling. The acceptability of the methodology used was evaluated by surveying the participating pharmacists. Results The symptom-based request was scored significantly better (a mean 2.17 out of a possible 4 points) than the direct product requests (means of 1.64 and 0.67 out of a possible 4 points for scenario 1 and 2, respectively). The most common information provided was dosage and adverse effects. Only the symptom-based request stimulated spontaneous counselling. No statistically significant differences in the duration of the consultation between the scenarios were found. There were also no significant differences in the quality of counselling between the Masters of Pharmacy and Pharmacy Technicians. The acceptability of the SP method was not as high as in other countries. Conclusion The assessment of paracetamol-related counselling demonstrates room for practice improvement. PMID:23300691

  13. On the numerical simulation of the laser absorption by Eulerian methods; Sur la simulation numerique de l'absorption laser par des methodes Euleriennes

    Energy Technology Data Exchange (ETDEWEB)

    Sentis, R. [CEA Bruyeres-le-Chatel, Dept. de Conception et Simulation des Armes, 91 (France); Golse, F. [CEA Saclay, Dept. de Modelisation des Systemes et Structures, 91 - Gif-sur-Yvette (France); Lafitte, O. [Paris-7 Univ., 75 (France)]|[Ecole Normale Superieure, 75 - Paris (France)

    2001-07-01

    For the simulation of the laser absorption in a plasma hydrodynamic code, one uses generally a ray tracing method. We show here where are the main difficulties related to a numerical solution of the eikonal equation by an alternative method called Eulerian. We indicate also what way are considered to clear up these difficulties. One of the main assets of the Eulerian method is to give a more regular estimation of the energy absorbed in each elementary volume than the ray-tracing method.

  14. Spectral methods for the uncertainties propagation in numerical simulation; Methodes spectrales robustes pour la propagation d'incertitudes en simulation numerique

    Energy Technology Data Exchange (ETDEWEB)

    Crestaux, Th. [CEA Saclay, Dept. Modelisation de Systemes et Structures (DEN/DANS/DM2S/SFME), 91 - Gif sur Yvette (France)

    2008-07-01

    The context of this thesis is the development of the numerical simulation in industrial processes. It aims to study and develop methods allowing a decrease of the numerical cost of calculi of Chaos Polynomials development. The implementing concerns problems of high stochastic dimension and more particularly the transport model of radionuclides in radioactive wastes disposal. (A.L.B.)

  15. Efficient simulation of stochastic chemical kinetics with the Stochastic Bulirsch-Stoer extrapolation method.

    Science.gov (United States)

    Székely, Tamás; Burrage, Kevin; Zygalakis, Konstantinos C; Barrio, Manuel

    2014-06-18

    Biochemical systems with relatively low numbers of components must be simulated stochastically in order to capture their inherent noise. Although there has recently been considerable work on discrete stochastic solvers, there is still a need for numerical methods that are both fast and accurate. The Bulirsch-Stoer method is an established method for solving ordinary differential equations that possesses both of these qualities. In this paper, we present the Stochastic Bulirsch-Stoer method, a new numerical method for simulating discrete chemical reaction systems, inspired by its deterministic counterpart. It is able to achieve an excellent efficiency due to the fact that it is based on an approach with high deterministic order, allowing for larger stepsizes and leading to fast simulations. We compare it to the Euler τ-leap, as well as two more recent τ-leap methods, on a number of example problems, and find that as well as being very accurate, our method is the most robust, in terms of efficiency, of all the methods considered in this paper. The problems it is most suited for are those with increased populations that would be too slow to simulate using Gillespie's stochastic simulation algorithm. For such problems, it is likely to achieve higher weak order in the moments. The Stochastic Bulirsch-Stoer method is a novel stochastic solver that can be used for fast and accurate simulations. Crucially, compared to other similar methods, it better retains its high accuracy when the timesteps are increased. Thus the Stochastic Bulirsch-Stoer method is both computationally efficient and robust. These are key properties for any stochastic numerical method, as they must typically run many thousands of simulations.

  16. Simulation of XPS C1s Spectra of Organic Monolayers by Quantum Chemical Methods

    NARCIS (Netherlands)

    Giesbers, M.; Marcelis, A.T.M.; Zuilhof, H.

    2013-01-01

    Several simple methods are presented and evaluated to simulate the X-ray photoelectron spectra (XPS) of organic monolayers and polymeric layers by density functional theory (DFT) and second-order Møller–Plesset theory (MP2) in combination with a series of basis sets. The simulated carbon (C1s) XPS

  17. An analytical method to simulate the H I 21-cm visibility signal for intensity mapping experiments

    Science.gov (United States)

    Sarkar, Anjan Kumar; Bharadwaj, Somnath; Marthi, Visweshwar Ram

    2018-01-01

    Simulations play a vital role in testing and validating H I 21-cm power spectrum estimation techniques. Conventional methods use techniques like N-body simulations to simulate the sky signal which is then passed through a model of the instrument. This makes it necessary to simulate the H I distribution in a large cosmological volume, and incorporate both the light-cone effect and the telescope's chromatic response. The computational requirements may be particularly large if one wishes to simulate many realizations of the signal. In this paper, we present an analytical method to simulate the H I visibility signal. This is particularly efficient if one wishes to simulate a large number of realizations of the signal. Our method is based on theoretical predictions of the visibility correlation which incorporate both the light-cone effect and the telescope's chromatic response. We have demonstrated this method by applying it to simulate the H I visibility signal for the upcoming Ooty Wide Field Array Phase I.

  18. Low-dissipation methods and models for the simulation of turbulent subsonic flow : Theory and applications

    NARCIS (Netherlands)

    Rozema, Wybe

    2015-01-01

    More and more often computer simulations of airflow are used as a tool in aircraft design. In this research project, which is a collaboration of the University of Groningen and the National Aerospace Laboratory NLR, new computer methods and models for the accurate simulation of airflow around

  19. Corrected momentum exchange method for lattice Boltzmann simulations of suspension flow

    NARCIS (Netherlands)

    Lorenz, E.; Caiazzo, A.; Hoekstra, A.G.

    2009-01-01

    Standard methods for lattice Boltzmann simulations of suspended particles, based on the momentum exchange algorithm, might lack accuracy or violate Galilean invariance in some particular situations. Aiming at simulations of dense suspensions in high-shear flows, we motivate and investigate necessary

  20. Simulation As a Method To Support Complex Organizational Transformations in Healthcare

    NARCIS (Netherlands)

    Rothengatter, D.C.F.; Katsma, Christiaan; van Hillegersberg, Jos

    2010-01-01

    In this paper we study the application of simulation as a method to support information system and process design in complex organizational transitions. We apply a combined use of a collaborative workshop approach with the use of a detailed and accurate graphical simulation model in a hospital that

  1. Discrete event simulation of crop operations in sweet pepper in support of work method innovation

    NARCIS (Netherlands)

    Ooster, van 't Bert; Aantjes, Wiger; Melamed, Z.

    2017-01-01

    Greenhouse Work Simulation, GWorkS, is a model that simulates crop operations in greenhouses for the purpose of analysing work methods. GWorkS is a discrete event model that approaches reality as a discrete stochastic dynamic system. GWorkS was developed and validated using cut-rose as a case

  2. Multi-class continuum traffic flow models : Analysis and simulation methods

    NARCIS (Netherlands)

    Van Wageningen-Kessels, F.L.M.

    2013-01-01

    How to model and simulate traffic flow including different vehicles such as cars and trucks? This dissertation answers this question by analyzing existing models and simulation methods and by developing new ones. The new model (Fastlane) describes traffic as a continuum flow while accounting for

  3. Impaired driving simulation in patients with Periodic Limb Movement Disorder and patients with Obstructive Sleep Apnea Syndrome.

    Science.gov (United States)

    Gieteling, Esther W; Bakker, Marije S; Hoekema, Aarnoud; Maurits, Natasha M; Brouwer, Wiebo H; van der Hoeven, Johannes H

    2012-05-01

    Excessive daytime sleepiness (EDS) is considered to be responsible for increased collision rate and impaired driving simulator performance in Obstructive Sleep Apnea Syndrome (OSAS) patients. Periodic Limb Movement Disorder (PLMD) patients also frequently report EDS and may also have impaired driving capacities. PLMD patients (n=16), OSAS patients (n=18), and controls (n=16) performed a monotonous 25-min driving simulation task. Parameters for driving capacity were the slope of the standard deviation of the lane position, lapses of attention (LOA), and structural deviations. The severity of sleep disruption and the degree of subjective sleepiness were measured. Slope and LOA were significantly higher in patients than controls, pointing to a decreased driving performance. At start patients and controls had similar driving capacity. The PLMD and OSAS groups did not differ on any scale or simulation performance, although OSAS patients generally performed worse. Subjective sleepiness was higher in patients than controls, and correlated positively with driving simulator parameters. Severity of the disorder and performance were uncorrelated. PLMD and OSAS patients showed impaired performance in a simulated monotonous driving task. At start, patients and controls performed similarly, but patient performance decreased clearly with time, suggesting that decreased vigilance as a result of disturbed sleep is an important component of deteriorated simulated and, possibly, real driving performance. Copyright © 2012 Elsevier B.V. All rights reserved.

  4. Using a computer simulation for teaching communication skills: A blinded multisite mixed methods randomized controlled trial.

    Science.gov (United States)

    Kron, Frederick W; Fetters, Michael D; Scerbo, Mark W; White, Casey B; Lypson, Monica L; Padilla, Miguel A; Gliva-McConvey, Gayle A; Belfore, Lee A; West, Temple; Wallace, Amelia M; Guetterman, Timothy C; Schleicher, Lauren S; Kennedy, Rebecca A; Mangrulkar, Rajesh S; Cleary, James F; Marsella, Stacy C; Becker, Daniel M

    2017-04-01

    To assess advanced communication skills among second-year medical students exposed either to a computer simulation (MPathic-VR) featuring virtual humans, or to a multimedia computer-based learning module, and to understand each group's experiences and learning preferences. A single-blinded, mixed methods, randomized, multisite trial compared MPathic-VR (N=210) to computer-based learning (N=211). Primary outcomes: communication scores during repeat interactions with MPathic-VR's intercultural and interprofessional communication scenarios and scores on a subsequent advanced communication skills objective structured clinical examination (OSCE). Multivariate analysis of variance was used to compare outcomes. student attitude surveys and qualitative assessments of their experiences with MPathic-VR or computer-based learning. MPathic-VR-trained students improved their intercultural and interprofessional communication performance between their first and second interactions with each scenario. They also achieved significantly higher composite scores on the OSCE than computer-based learning-trained students. Attitudes and experiences were more positive among students trained with MPathic-VR, who valued its providing immediate feedback, teaching nonverbal communication skills, and preparing them for emotion-charged patient encounters. MPathic-VR was effective in training advanced communication skills and in enabling knowledge transfer into a more realistic clinical situation. MPathic-VR's virtual human simulation offers an effective and engaging means of advanced communication training. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  5. Explicit Singly Diagonally Implicit Runge-Kutta Methods and Adaptive Stepsize Control for Reservoir Simulation

    DEFF Research Database (Denmark)

    Völcker, Carsten; Jørgensen, John Bagterp; Thomsen, Per Grove

    2010-01-01

    The implicit Euler method, normally refered to as the fully implicit (FIM) method, and the implicit pressure explicit saturation (IMPES) method are the traditional choices for temporal discretization in reservoir simulation. The FIM method offers unconditionally stability in the sense of discrete....... Current reservoir simulators apply timestepping algorithms that are based on safeguarded heuristics, and can neither guarantee convergence in the underlying equation solver, nor provide estimates of the relations between convergence, integration error and stepsizes. We establish predictive stepsize...... control applied to high order methods for temporal discretization in reservoir simulation. The family of Runge-Kutta methods is presented and in particular the explicit singly diagonally implicit Runge-Kutta (ESDIRK) method with an embedded error estimate is described. A predictive stepsize adjustment...

  6. Implicit large-eddy simulation of compressible flows using the Interior Embedded Discontinuous Galerkin method

    CERN Document Server

    Fernandez, Pablo; Roca, Xevi; Peraire, Jaime

    2016-01-01

    We present a high-order implicit large-eddy simulation (ILES) approach for simulating transitional turbulent flows. The approach consists of an Interior Embedded Discontinuous Galerkin (IEDG) method for the discretization of the compressible Navier-Stokes equations and a parallel preconditioned Newton-GMRES solver for the resulting nonlinear system of equations. The IEDG method arises from the marriage of the Embedded Discontinuous Galerkin (EDG) method and the Hybridizable Discontinuous Galerkin (HDG) method. As such, the IEDG method inherits the advantages of both the EDG method and the HDG method to make itself well-suited for turbulence simulations. We propose a minimal residual Newton algorithm for solving the nonlinear system arising from the IEDG discretization of the Navier-Stokes equations. The preconditioned GMRES algorithm is based on a restricted additive Schwarz (RAS) preconditioner in conjunction with a block incomplete LU factorization at the subdomain level. The proposed approach is applied to...

  7. Monte Carlo probabilistic sensitivity analysis for patient level simulation models: efficient estimation of mean and variance using ANOVA.

    Science.gov (United States)

    O'Hagan, Anthony; Stevenson, Matt; Madan, Jason

    2007-10-01

    Probabilistic sensitivity analysis (PSA) is required to account for uncertainty in cost-effectiveness calculations arising from health economic models. The simplest way to perform PSA in practice is by Monte Carlo methods, which involves running the model many times using randomly sampled values of the model inputs. However, this can be impractical when the economic model takes appreciable amounts of time to run. This situation arises, in particular, for patient-level simulation models (also known as micro-simulation or individual-level simulation models), where a single run of the model simulates the health care of many thousands of individual patients. The large number of patients required in each run to achieve accurate estimation of cost-effectiveness means that only a relatively small number of runs is possible. For this reason, it is often said that PSA is not practical for patient-level models. We develop a way to reduce the computational burden of Monte Carlo PSA for patient-level models, based on the algebra of analysis of variance. Methods are presented to estimate the mean and variance of the model output, with formulae for determining optimal sample sizes. The methods are simple to apply and will typically reduce the computational demand very substantially. John Wiley & Sons, Ltd.

  8. A practical cone-beam CT scatter correction method with optimized Monte Carlo simulations for image-guided radiation therapy

    Science.gov (United States)

    Xu, Yuan; Bai, Ti; Yan, Hao; Ouyang, Luo; Pompos, Arnold; Wang, Jing; Zhou, Linghong; Jiang, Steve B.; Jia, Xun

    2015-05-01

    Cone-beam CT (CBCT) has become the standard image guidance tool for patient setup in image-guided radiation therapy. However, due to its large illumination field, scattered photons severely degrade its image quality. While kernel-based scatter correction methods have been used routinely in the clinic, it is still desirable to develop Monte Carlo (MC) simulation-based methods due to their accuracy. However, the high computational burden of the MC method has prevented routine clinical application. This paper reports our recent development of a practical method of MC-based scatter estimation and removal for CBCT. In contrast with conventional MC approaches that estimate scatter signals using a scatter-contaminated CBCT image, our method used a planning CT image for MC simulation, which has the advantages of accurate image intensity and absence of image truncation. In our method, the planning CT was first rigidly registered with the CBCT. Scatter signals were then estimated via MC simulation. After scatter signals were removed from the raw CBCT projections, a corrected CBCT image was reconstructed. The entire workflow was implemented on a GPU platform for high computational efficiency. Strategies such as projection denoising, CT image downsampling, and interpolation along the angular direction were employed to further enhance the calculation speed. We studied the impact of key parameters in the workflow on the resulting accuracy and efficiency, based on which the optimal parameter values were determined. Our method was evaluated in numerical simulation, phantom, and real patient cases. In the simulation cases, our method reduced mean HU errors from 44 to 3 HU and from 78 to 9 HU in the full-fan and the half-fan cases, respectively. In both the phantom and the patient cases, image artifacts caused by scatter, such as ring artifacts around the bowtie area, were reduced. With all the techniques employed, we achieved computation time of less than 30 s including the

  9. Simulated annealing method for electronic circuits design: adaptation and comparison with other optimization methods; La methode du recuit simule pour la conception des circuits electroniques: adaptation et comparaison avec d`autres methodes d`optimisation

    Energy Technology Data Exchange (ETDEWEB)

    Berthiau, G.

    1995-10-01

    The circuit design problem consists in determining acceptable parameter values (resistors, capacitors, transistors geometries ...) which allow the circuit to meet various user given operational criteria (DC consumption, AC bandwidth, transient times ...). This task is equivalent to a multidimensional and/or multi objective optimization problem: n-variables functions have to be minimized in an hyper-rectangular domain ; equality constraints can be eventually specified. A similar problem consists in fitting component models. In this way, the optimization variables are the model parameters and one aims at minimizing a cost function built on the error between the model response and the data measured on the component. The chosen optimization method for this kind of problem is the simulated annealing method. This method, provided by the combinatorial optimization domain, has been adapted and compared with other global optimization methods for the continuous variables problems. An efficient strategy of variables discretization and a set of complementary stopping criteria have been proposed. The different parameters of the method have been adjusted with analytical functions of which minima are known, classically used in the literature. Our simulated annealing algorithm has been coupled with an open electrical simulator SPICE-PAC of which the modular structure allows the chaining of simulations required by the circuit optimization process. We proposed, for high-dimensional problems, a partitioning technique which ensures proportionality between CPU-time and variables number. To compare our method with others, we have adapted three other methods coming from combinatorial optimization domain - the threshold method, a genetic algorithm and the Tabu search method - The tests have been performed on the same set of test functions and the results allow a first comparison between these methods applied to continuous optimization variables. (Abstract Truncated)

  10. An in vitro patient-tailored model of human cerebral artery for simulating endovascular intervention.

    Science.gov (United States)

    Ikeda, Seiichi; Arai, Fumihito; Fukuda, Toshio; Negoro, Makoto; Irie, Keiko; Takahashi, Ikuo

    2005-01-01

    An in vitro patient-tailored reproduction model of cerebral artery, a hardware platform for simulating endovascular intervention for making diagnoses and surgical trainings is presented. 3-D configuration of vessel lumen is reproduced as vessel model with 13 microm modeling resolution, using CT and MRI information. Physical characteristics of cerebral artery, such as elastic modulus and friction coefficient, are also reproduced. We also propose a novel method to visualize stress condition on vessel wall using photoelastic effect. Consequently, it should be helpful for clinical applications, academic researches and other various purposes.

  11. Impact of routine follow-up examinations on life expectancy in ovarian cancer patients: a simulation study.

    NARCIS (Netherlands)

    Geurts, S.M.E.; Vegt, F. de; Altena, A.M. van; Tjan-Heijnen, V.C.; Massuger, L.F.A.G.; Adang, E.M.M.; Dijck, J.A.A.M. van; Verbeek, A.L.M.

    2012-01-01

    OBJECTIVE: The clinical benefit of routine follow-up in patients treated for ovarian cancer is subject to debate. In this study, the magnitude of the potential survival benefit of routine examinations was evaluated by Markov modeling. METHODS: The clinical course of ovarian cancer was simulated

  12. The moral aesthetics of simulated suffering in standardized patient performances.

    Science.gov (United States)

    Taylor, Janelle S

    2011-06-01

    Standardized patient (SP) performances are staged clinical encounters between health-professional students and people who specialize in role-playing the part of patients. Such performances have in recent years become increasingly central to the teaching and assessment of clinical skills in U.S. medical schools. SP performances are valued for being both "real" (in that they involve interaction with a real person, unlike written examinations) and "not real" (in that the SP does not actually suffer from the condition portrayed, unlike an actual patient). This article considers how people involved in creating SP performances reconcile a moral commitment to avoid suffering (to keep it "not real"), with an aesthetic commitment to realistically portray it (to keep it "real"). The term "moral aesthetic" is proposed, to indicate a sensibility that combines ideas about what is morally right with ideas about what is aesthetically compelling. Drawing on ethnographic research among SPs and SP program staff and medical faculty who work closely with them, this article argues that their work of creating "realism" in simulated clinical encounters encompasses multiple different (and sometimes conflicting) understandings and practices of realism, informed by three different moral aesthetics: (1) a moral aesthetic of induction, in which an accurate portrayal with a well-documented provenance serves to introduce experientially distant forms of suffering; (2) a moral aesthetic of inoculation, in which the authenticity and emotional impact of a performance are meant to inoculate students against the impact of future encounters with suffering; (3) a moral aesthetic of presence, generating forms of voice and care that are born out of the embodied presence of suffering individuals in a clinical space. All are premised on the assumption that risk and suffering can be banished from SP performances. This article suggests, however, that SP performances necessarily raise the same difficult

  13. Non-analogue Monte Carlo method, application to neutron simulation; Methode de Monte Carlo non analogue, application a la simulation des neutrons

    Energy Technology Data Exchange (ETDEWEB)

    Morillon, B.

    1996-12-31

    With most of the traditional and contemporary techniques, it is still impossible to solve the transport equation if one takes into account a fully detailed geometry and if one studies precisely the interactions between particles and matters. Only the Monte Carlo method offers such a possibility. However with significant attenuation, the natural simulation remains inefficient: it becomes necessary to use biasing techniques where the solution of the adjoint transport equation is essential. The Monte Carlo code Tripoli has been using such techniques successfully for a long time with different approximate adjoint solutions: these methods require from the user to find out some parameters. If this parameters are not optimal or nearly optimal, the biases simulations may bring about small figures of merit. This paper presents a description of the most important biasing techniques of the Monte Carlo code Tripoli ; then we show how to calculate the importance function for general geometry with multigroup cases. We present a completely automatic biasing technique where the parameters of the biased simulation are deduced from the solution of the adjoint transport equation calculated by collision probabilities. In this study we shall estimate the importance function through collision probabilities method and we shall evaluate its possibilities thanks to a Monte Carlo calculation. We compare different biased simulations with the importance function calculated by collision probabilities for one-group and multigroup problems. We have run simulations with new biasing method for one-group transport problems with isotropic shocks and for multigroup problems with anisotropic shocks. The results show that for the one-group and homogeneous geometry transport problems the method is quite optimal without splitting and russian roulette technique but for the multigroup and heterogeneous X-Y geometry ones the figures of merit are higher if we add splitting and russian roulette technique.

  14. Assessing methods for dealing with treatment switching in clinical trials: A follow-up simulation study.

    Science.gov (United States)

    Latimer, Nicholas R; Abrams, Keith R; Lambert, Paul C; Morden, James P; Crowther, Michael J

    2018-03-01

    When patients randomised to the control group of a randomised controlled trial are allowed to switch onto the experimental treatment, intention-to-treat analyses of the treatment effect are confounded because the separation of randomised groups is lost. Previous research has investigated statistical methods that aim to estimate the treatment effect that would have been observed had this treatment switching not occurred and has demonstrated their performance in a limited set of scenarios. Here, we investigate these methods in a new range of realistic scenarios, allowing conclusions to be made based upon a broader evidence base. We simulated randomised controlled trials incorporating prognosis-related treatment switching and investigated the impact of sample size, reduced switching proportions, disease severity, and alternative data-generating models on the performance of adjustment methods, assessed through a comparison of bias, mean squared error, and coverage, related to the estimation of true restricted mean survival in the absence of switching in the control group. Rank preserving structural failure time models, inverse probability of censoring weights, and two-stage methods consistently produced less bias than the intention-to-treat analysis. The switching proportion was confirmed to be a key determinant of bias: sample size and censoring proportion were relatively less important. It is critical to determine the size of the treatment effect in terms of an acceleration factor (rather than a hazard ratio) to provide information on the likely bias associated with rank-preserving structural failure time model adjustments. In general, inverse probability of censoring weight methods are more volatile than other adjustment methods.

  15. A comparative study of divergence cleaning methods of magnetic field in the solar coronal numerical simulation

    Directory of Open Access Journals (Sweden)

    Xueshang eFeng

    2016-03-01

    Full Text Available This paper presents a comparative study of divergence cleaning methods of magnetic field in the solar coronal three-dimensional numerical simulation. For such purpose, the diffusive method, projection method, generalized Lagrange multiplier method and constrained-transport method are used. All these methods are combined with a finite-volume scheme based on a six-component grid system in spherical coordinates. In order to see the performance between the four divergence cleaning methods, solar coronal numerical simulation for Carrington rotation 2056 has been studied. Numerical results show that the average relative divergence error is around $10^{-4.5}$ for the constrained-transport method, while about $10^{-3.1}- 10^{-3.6}$ for the other three methods. Although there exist some differences in the average relative divergence errors for the four employed methods, our tests show they can all produce basic structured solar wind.

  16. Explicit Singly Diagonally Implicit Runge-Kutta Methods and Adaptive Stepsize Control for Reservoir Simulation

    DEFF Research Database (Denmark)

    Völcker, Carsten; Jørgensen, John Bagterp; Thomsen, Per Grove

    2010-01-01

    The implicit Euler method, normally refered to as the fully implicit (FIM) method, and the implicit pressure explicit saturation (IMPES) method are the traditional choices for temporal discretization in reservoir simulation. The FIM method offers unconditionally stability in the sense of discrete......-Kutta methods, ESDIRK, Newton-Raphson, convergence control, error control, stepsize selection.......The implicit Euler method, normally refered to as the fully implicit (FIM) method, and the implicit pressure explicit saturation (IMPES) method are the traditional choices for temporal discretization in reservoir simulation. The FIM method offers unconditionally stability in the sense of discrete...... approximations, while the IMPES scheme benefits from the explicit treatment of the saturation. However, in tems of controlling the integration error, the low order of the FIM method leads to small integration steps, while the explicit treatment of the saturation may restrict the stepsizes for the IMPES scheme...

  17. A Fast Finite-Difference Time Domain Simulation Method for the Source-Stirring Reverberation Chamber

    Directory of Open Access Journals (Sweden)

    Wenxing Li

    2017-01-01

    Full Text Available Numerical analysis methods are often employed to improve the efficiency of the design and application of the source-stirring reverberation chamber. However, the state of equilibrium of the field inside the chamber is hard to reach. In this paper, we present a fast simulation method, which is able to significantly decrease the simulation time of the source-stirring reverberation chamber. The mathematical model of this method is given in detail and home-made FDTD code is employed to conduct the simulations and optimizations as well. The results show that the implementation of the method can give us the accurate frequency response of the source-stirring chamber and make the simulation of source-stirring chamber more efficient.

  18. Reliability Assessment of Active Distribution System Using Monte Carlo Simulation Method

    Directory of Open Access Journals (Sweden)

    Shaoyun Ge

    2014-01-01

    Full Text Available In this paper we have treated the reliability assessment problem of low and high DG penetration level of active distribution system using the Monte Carlo simulation method. The problem is formulated as a two-case program, the program of low penetration simulation and the program of high penetration simulation. The load shedding strategy and the simulation process were introduced in detail during each FMEA process. Results indicate that the integration of DG can improve the reliability of the system if the system was operated actively.

  19. Simulation embedded artificial intelligence search method for supplier trading portfolio decision

    DEFF Research Database (Denmark)

    Feng, Donghan; Yan, Z.; Østergaard, Jacob

    2010-01-01

    . The simulation results also reveal the accumulation effect along trading period, which will improve the normality of the supplier trading portfolios. The authors believe the proposed method is a useful complement for the MV method and conditional value at risk (CVaR)-based methods in the supplier trading...

  20. Methods to Estimate the Variance of Some Indices of the Signal Detection Theory: A Simulation Study

    Science.gov (United States)

    Suero, Manuel; Privado, Jesús; Botella, Juan

    2017-01-01

    A simulation study is presented to evaluate and compare three methods to estimate the variance of the estimates of the parameters d and "C" of the signal detection theory (SDT). Several methods have been proposed to calculate the variance of their estimators, "d'" and "c." Those methods have been mostly assessed by…

  1. METHODS OF SIMULATION ON THE MAP OF ETHNOGEOGRAPHICAL KNOWLEDGE

    Directory of Open Access Journals (Sweden)

    A. M. Saraeva

    2017-01-01

    Full Text Available The article deals with the features of the spatial representation of the location of objects and phenomena on the Earth. One of the types of “cartographic representation” is modeling on the contour map. The advantages of the method are revealed. The application of modeling techniques that allows one to include ethnogeographic data in the content of the characteristics of the territory and reflect them on the contour map. The basis of ethnogeographic modeling is the identification and creation of elements of the material and spiritual culture of peoples by means of conventional signs. Comparison of these elements, their superimposition with respect to each other, as well as their comparison with geographic maps allow us to determine the interrelations and the dependence of the phenomenon. Modeling on contour maps is the basic method of learning in geography. On the one hand, it creates a cartographic image of the studied territory, and on the other hand it facilitates the creation of “visual supports” on the map.Modeling on contour maps, at the beginning students put the basic geographical names, which will serve as the basic knowledge. Then, by purposefully analyzing and comparing the thematic maps of the atlas or textbook, the students reflect specific ethno-geographical knowledge on contour maps. As a result, contour maps acquire “their own face”, and do not become a simple copy of maps of an atlas or textbook.Also, the features of the effect of this technique on the formation of spatial representations about the studied object have been analyzed. Thanks to the cartographic model, one can maintain a constant cognitive interest in the material studied. Modeling on the contour map will allow one to present the structure of the links between the elements of the ethnogeographical material. The basis of ethnogeographic modeling on the contour map is the identification and mapping of elements of the material and spiritual culture of

  2. A stable cutting method for finite elements based virtual surgery simulation.

    Science.gov (United States)

    Jerábková, Lenka; Jerábek, Jakub; Chudoba, Rostislav; Kuhlen, Torsten

    2007-01-01

    In this paper we present a novel approach for stable interactive cutting of deformable objects in virtual environments. Our method is based on the extended finite elements method, allowing for a modeling of discontinuities without remeshing. As no new elements are created, the impact on simulation performance is minimized. We also propose an appropriate mass lumping technique to guarantee for the stability of the simulation regardless of the position of the cut.

  3. A Study of Different Modeling Choices For Simulating Platelets Within the Immersed Boundary Method

    OpenAIRE

    Shankar, Varun; Wright, Grady B.; Fogelson, Aaron L.; Kirby, Robert M.

    2012-01-01

    The Immersed Boundary (IB) method is a widely-used numerical methodology for the simulation of fluid–structure interaction problems. The IB method utilizes an Eulerian discretization for the fluid equations of motion while maintaining a Lagrangian representation of structural objects. Operators are defined for transmitting information (forces and velocities) between these two representations. Most IB simulations represent their structures with piecewise linear approximations and utilize Hooke...

  4. Computer Simulation Methods for Crushing Process in an Jaw Crusher

    Science.gov (United States)

    Il'ich Beloglazov, Ilia; Andreevich Ikonnikov, Dmitrii

    2016-08-01

    One of the trends at modern mining enterprises is the application of combined systems for extraction and transportation of the rock mass. Given technology involves the use the conveyor lines as a continuous link of combined technology. The application of a conveyor transport provides significant reduction of costs for energy resources, increase in labor productivity and process automation. However, the use of a conveyor transport provides for certain requirements for the quality of transported material. The maximum size of the rock mass pieces is one of the basic parameters for it. The crushing plants applies as a coarse crushing followed by crushing the material to the maximum size of piece which possible to use for conveyor transport. It is often represented by jaw crushers. Modelling of crushing process in jaw crushers allows to maximally optimize workflow and increase efficiency of the equipment at the further transportation and processing of rocks. We studied the interaction between walls of the jaw crusher and bulk material by using discrete element method (DEM) in this paper. The article examines the process of modeling by stages. It includes design of the crusher construction in solid and surface modeling system. Modelling of the crushing process based on the experimental data received via the crushing unit BOYD. The process of destruction and particle size distribution in the study was done. Analysis of research results shows a comparability of actual experiment and modeling process.

  5. Weighted Least-Squares Finite Element Method for Cardiac Blood Flow Simulation with Echocardiographic Data

    Directory of Open Access Journals (Sweden)

    Fei Wei

    2012-01-01

    Full Text Available As both fluid flow measurement techniques and computer simulation methods continue to improve, there is a growing need for numerical simulation approaches that can assimilate experimental data into the simulation in a flexible and mathematically consistent manner. The problem of interest here is the simulation of blood flow in the left ventricle with the assimilation of experimental data provided by ultrasound imaging of microbubbles in the blood. The weighted least-squares finite element method is used because it allows data to be assimilated in a very flexible manner so that accurate measurements are more closely matched with the numerical solution than less accurate data. This approach is applied to two different test problems: a flexible flap that is displaced by a jet of fluid and blood flow in the porcine left ventricle. By adjusting how closely the simulation matches the experimental data, one can observe potential inaccuracies in the model because the simulation without experimental data differs significantly from the simulation with the data. Additionally, the assimilation of experimental data can help the simulation capture certain small effects that are present in the experiment, but not modeled directly in the simulation.

  6. Weighted least-squares finite element method for cardiac blood flow simulation with echocardiographic data.

    Science.gov (United States)

    Wei, Fei; Westerdale, John; McMahon, Eileen M; Belohlavek, Marek; Heys, Jeffrey J

    2012-01-01

    As both fluid flow measurement techniques and computer simulation methods continue to improve, there is a growing need for numerical simulation approaches that can assimilate experimental data into the simulation in a flexible and mathematically consistent manner. The problem of interest here is the simulation of blood flow in the left ventricle with the assimilation of experimental data provided by ultrasound imaging of microbubbles in the blood. The weighted least-squares finite element method is used because it allows data to be assimilated in a very flexible manner so that accurate measurements are more closely matched with the numerical solution than less accurate data. This approach is applied to two different test problems: a flexible flap that is displaced by a jet of fluid and blood flow in the porcine left ventricle. By adjusting how closely the simulation matches the experimental data, one can observe potential inaccuracies in the model because the simulation without experimental data differs significantly from the simulation with the data. Additionally, the assimilation of experimental data can help the simulation capture certain small effects that are present in the experiment, but not modeled directly in the simulation.

  7. Evaluation of a proposed optimization method for discrete-event simulation models

    Directory of Open Access Journals (Sweden)

    Alexandre Ferreira de Pinho

    2012-12-01

    Full Text Available Optimization methods combined with computer-based simulation have been utilized in a wide range of manufacturing applications. However, in terms of current technology, these methods exhibit low performance levels which are only able to manipulate a single decision variable at a time. Thus, the objective of this article is to evaluate a proposed optimization method for discrete-event simulation models based on genetic algorithms which exhibits more efficiency in relation to computational time when compared to software packages on the market. It should be emphasized that the variable's response quality will not be altered; that is, the proposed method will maintain the solutions' effectiveness. Thus, the study draws a comparison between the proposed method and that of a simulation instrument already available on the market and has been examined in academic literature. Conclusions are presented, confirming the proposed optimization method's efficiency.

  8. A Simulation Method for High-Cycle Fatigue-Driven Delamination using a Cohesive Zone Model

    DEFF Research Database (Denmark)

    Bak, Brian Lau Verndal; Turon, A.; Lindgaard, Esben

    2016-01-01

    A novel computational method for simulating fatigue-driven mixed-mode delamination cracks in laminated structures under cyclic loading is presented. The proposed fatigue method is based on linking a cohesive zone model for quasi-static crack growth and a Paris' law-like model described...... on parameter fitting of any kind. The method has been implemented as a zero-thickness eight-node interface element for Abaqus and as a spring element for a simple finite element model in MATLAB. The method has been validated in simulations of mode I, mode II, and mixed-mode crack loading for both self......-similar and non-self-similar crack propagation. The method produces highly accurate results compared with currently available methods and is capable of simulating general mixed-mode non-self-similar crack growth problems....

  9. Evaluation of a novel method of teaching endobronchial ultrasound: physician- versus respiratory therapist-proctored simulation training.

    Science.gov (United States)

    Stather, David Ryan; Chee, Alex; Maceachern, Paul; Dumoulin, Elaine; Hergott, Christopher A; Gelberg, Jacob; Scott, Sandra D; De Guzman, Sylvia; Tremblay, Alain

    2013-01-01

    Computer endobronchial ultrasound (EBUS) simulators have been demonstrated to improve trainee procedural skills before attempting to perform EBUS procedures on patients. To compare EBUS performance following training with computer simulation proctored by EBUS-trained respiratory therapists versus the same simulation training proctored by an interventional respirologist. The present analysis was a prospective study of respiratory medicine trainees learning EBUS. Two cohorts of trainees were evaluated using a previously validated method using simulated cases with performance metrics measured by the simulator. Group 1 underwent EBUS training by performing 15 procedures on an EBUS simulator (n=4) proctored by an interventional respirologist. Group 2 received identical training proctored by a respiratory therapist with special training in EBUS (n=10). No significant differences between group 1 and group 2 were apparent for the primary outcome measures of total procedure time (15.15±1.34 min versus 14.78±2.88 min; P=0.816), the percentage of lymph nodes successfully identified (88.8±5.4 versus 80.91±8.9; P=0.092) or the percentage of successful biopsies (100.0±0.0 versus 98.75±3.95; P=0.549). The learning curves were similar between groups, and did not show an obvious plateau after 19 simulated procedures in either group. Acquisition of basic EBUS technical skills can be achieved using computer EBUS simulation proctored by specially trained respiratory therapists or by an interventional respirologist. There appeared to be no significant advantage to having an interventional respirologist proctor the computer EBUS simulation.

  10. Simulation of thermal behavior of residential buildings using fuzzy active learning method

    Directory of Open Access Journals (Sweden)

    Masoud Taheri Shahraein

    2015-01-01

    Full Text Available In this paper, a fuzzy modeling technique called Modified Active Learning Method (MALM was introduced and utilized for fuzzy simulation of indoor and inner surface temperatures in residential buildings using meteorological data and its capability for fuzzy simulation was compared with other studies. The case studies for simulations were two residential apartments in the Fakouri and Rezashahr neighborhoods of Mashhad, Iran. The hourly inner surface and indoor temperature data were accumulated during measurements taken in 2010 and 2011 in different rooms of the apartments under heating and natural ventilation conditions. Hourly meteorological data (dry bulb temperature, wind speed and direction and solar radiation were measured by a meteorological station and utilized with zero to three hours lags as input variables for the simulation of inner surface and indoor temperatures. The results of simulations demonstrated the capability of MALM to be used for nonlinear fuzzy simulation of inner surface and indoor temperatures in residential apartments.

  11. INTEGRATING DATA ANALYTICS AND SIMULATION METHODS TO SUPPORT MANUFACTURING DECISION MAKING

    Science.gov (United States)

    Kibira, Deogratias; Hatim, Qais; Kumara, Soundar; Shao, Guodong

    2017-01-01

    Modern manufacturing systems are installed with smart devices such as sensors that monitor system performance and collect data to manage uncertainties in their operations. However, multiple parameters and variables affect system performance, making it impossible for a human to make informed decisions without systematic methodologies and tools. Further, the large volume and variety of streaming data collected is beyond simulation analysis alone. Simulation models are run with well-prepared data. Novel approaches, combining different methods, are needed to use this data for making guided decisions. This paper proposes a methodology whereby parameters that most affect system performance are extracted from the data using data analytics methods. These parameters are used to develop scenarios for simulation inputs; system optimizations are performed on simulation data outputs. A case study of a machine shop demonstrates the proposed methodology. This paper also reviews candidate standards for data collection, simulation, and systems interfaces. PMID:28690363

  12. Core Spreading Vortex Method for Simulating 3D Flows Around Bluff Bodies

    Directory of Open Access Journals (Sweden)

    Lavi R. Zuhal

    2014-12-01

    Full Text Available This paper presents the development of core spreading vortex element method, which is a mesh-free method, for simulating 3D viscous flow over bluff bodies. The developed method simulates external flow around complex geometry by tracking local velocities and vorticities of particles introduced within the fluid domain. The viscous effect is modeled using core spreading method coupled with the splitting spatial adaption scheme, and a smoothing interpolation scheme for overlapping issue and population control, respectively. The particle’s velocity is calculated using Biot-Savart formulation. To accelerate computation, Fast Multipole Method (FMM is employed. The solver is validated, for both unbounded and bounded flows at low Reynolds numbers, using a number of benchmark problems. For unbounded case, simulation of the collision of two vortex rings was performed. To test the performance of the method in simulating bounded flow problem, simulation of flow around a sphere was carried out. The results are found to be in good agreement with those reported in literatures and also simulations using other diffusion model.

  13. Simulation and characterization of stress in FinFETs using novel LKMC and nanobeam diffraction methods

    Science.gov (United States)

    Yiluan, Guo; Guilei, Wang; Chao, Zhao; Jun, Luo

    2015-08-01

    A new simulation method and test instrument has been adopted to verify the traditional stress simulation in FinFET. First, a new algorithm named lattice kinetic Monte Carlo (LKMC) is used to simulate the SiGe epitaxy in source/drain regions and the stress distribution is consequently extracted after the LKMC simulation. Systematic comparison between the traditional polyhedron method and the LKMC method is carried out. The results confirm that extracted stress from both methods is consistent, which verifies the validity of traditional polyhedron method for the purpose of simulating stress in FinFET. In the following experiment, p-type FinFETs with SiGe stressors in source/drain regions are fabricated. The nano beam diffraction (NBD) method is employed to characterize the strain in Si fin. The strain value from the NBD test agrees well with the value extracted from traditional polyhedron simulation. Project supported by the “National S&T Major Project 02”, the Opening Project of Microelectronics Devices & Bulk Si FinFET Integrated Technology, Institute of Microelectronics, Chinese Academy of Sciences (No. 2013ZX02303007-001).

  14. Simulations

    CERN Document Server

    Ngada, Narcisse

    2015-06-15

    The complexity and cost of building and running high-power electrical systems make the use of simulations unavoidable. The simulations available today provide great understanding about how systems really operate. This paper helps the reader to gain an insight into simulation in the field of power converters for particle accelerators. Starting with the definition and basic principles of simulation, two simulation types, as well as their leading tools, are presented: analog and numerical simulations. Some practical applications of each simulation type are also considered. The final conclusion then summarizes the main important items to keep in mind before opting for a simulation tool or before performing a simulation.

  15. Methods for Computationally Efficient Structured CFD Simulations of Complex Turbomachinery Flows

    Science.gov (United States)

    Herrick, Gregory P.; Chen, Jen-Ping

    2012-01-01

    This research presents more efficient computational methods by which to perform multi-block structured Computational Fluid Dynamics (CFD) simulations of turbomachinery, thus facilitating higher-fidelity solutions of complicated geometries and their associated flows. This computational framework offers flexibility in allocating resources to balance process count and wall-clock computation time, while facilitating research interests of simulating axial compressor stall inception with more complete gridding of the flow passages and rotor tip clearance regions than is typically practiced with structured codes. The paradigm presented herein facilitates CFD simulation of previously impractical geometries and flows. These methods are validated and demonstrate improved computational efficiency when applied to complicated geometries and flows.

  16. Geant4 based Monte Carlo simulation for verifying the modified sum-peak method.

    Science.gov (United States)

    Aso, Tsukasa; Ogata, Yoshimune; Makino, Ryuta

    2017-09-14

    The modified sum-peak method can practically estimate radioactivity by using solely the peak and the sum peak count rate. In order to efficiently verify the method in various experimental conditions, a Geant4 based Monte Carlo simulation for a high-purity germanium detector system was applied. The energy spectra in the detector were simulated for a 60Co point source in various source to detector distances. The calculated radioactivity shows good agreement with the number of decays in the simulation. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. A method for data handling numerical results in parallel OpenFOAM simulations

    Energy Technology Data Exchange (ETDEWEB)

    Anton, Alin [Faculty of Automatic Control and Computing, Politehnica University of Timişoara, 2" n" d Vasile Pârvan Ave., 300223, TM Timişoara, Romania, alin.anton@cs.upt.ro (Romania); Muntean, Sebastian [Center for Advanced Research in Engineering Science, Romanian Academy – Timişoara Branch, 24" t" h Mihai Viteazu Ave., 300221, TM Timişoara (Romania)

    2015-12-31

    Parallel computational fluid dynamics simulations produce vast amount of numerical result data. This paper introduces a method for reducing the size of the data by replaying the interprocessor traffic. The results are recovered only in certain regions of interest configured by the user. A known test case is used for several mesh partitioning scenarios using the OpenFOAM toolkit{sup ®}[1]. The space savings obtained with classic algorithms remain constant for more than 60 Gb of floating point data. Our method is most efficient on large simulation meshes and is much better suited for compressing large scale simulation results than the regular algorithms.

  18. Hybrid statistics-simulations based method for atom-counting from ADF STEM images.

    Science.gov (United States)

    De Wael, Annelies; De Backer, Annick; Jones, Lewys; Nellist, Peter D; Van Aert, Sandra

    2017-06-01

    A hybrid statistics-simulations based method for atom-counting from annular dark field scanning transmission electron microscopy (ADF STEM) images of monotype crystalline nanostructures is presented. Different atom-counting methods already exist for model-like systems. However, the increasing relevance of radiation damage in the study of nanostructures demands a method that allows atom-counting from low dose images with a low signal-to-noise ratio. Therefore, the hybrid method directly includes prior knowledge from image simulations into the existing statistics-based method for atom-counting, and accounts in this manner for possible discrepancies between actual and simulated experimental conditions. It is shown by means of simulations and experiments that this hybrid method outperforms the statistics-based method, especially for low electron doses and small nanoparticles. The analysis of a simulated low dose image of a small nanoparticle suggests that this method allows for far more reliable quantitative analysis of beam-sensitive materials. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Shock waves simulated using the dual domain material point method combined with molecular dynamics

    Science.gov (United States)

    Zhang, Duan Z.; Dhakal, Tilak R.

    2017-04-01

    In this work we combine the dual domain material point method with molecular dynamics in an attempt to create a multiscale numerical method to simulate materials undergoing large deformations with high strain rates. In these types of problems, the material is often in a thermodynamically nonequilibrium state, and conventional constitutive relations or equations of state are often not available. In this method, the closure quantities, such as stress, at each material point are calculated from a molecular dynamics simulation of a group of atoms surrounding the material point. Rather than restricting the multiscale simulation in a small spatial region, such as phase interfaces, or crack tips, this multiscale method can be used to consider nonequilibrium thermodynamic effects in a macroscopic domain. This method takes the advantage that the material points only communicate with mesh nodes, not among themselves; therefore molecular dynamics simulations for material points can be performed independently in parallel. The dual domain material point method is chosen for this multiscale method because it can be used in history dependent problems with large deformation without generating numerical noise as material points move across cells, and also because of its convergence and conservation properties. To demonstrate the feasibility and accuracy of this method, we compare the results of a shock wave propagation in a cerium crystal calculated using the direct molecular dynamics simulation with the results from this combined multiscale calculation.

  20. Understanding the impact of simulated patients on health care learners' communication skills: a systematic review.

    Science.gov (United States)

    Kaplonyi, Jessica; Bowles, Kelly-Ann; Nestel, Debra; Kiegaldie, Debra; Maloney, Stephen; Haines, Terry; Williams, Cylie

    2017-12-01

    Effective communication skills are at the core of good health care. Simulated patients (SPs) are increasingly engaged as an interactive means of teaching, applying and practising communication skills with immediate feedback. There is a large body of research into the use of manikin-based simulation but a gap exists in the body of research on the effectiveness of SP-based education to teach communication skills that impact patient outcomes. The aim of this systematic review was to critically analyse the existing research, investigating whether SP-based communication skills training improves learner-patient communication, how communication skill improvement is measured, and who measures these improvements. The databases Medline, ProQuest (Health & Medical Complete, Nursing and Allied Health Source) and CINAHL (EBSCOhost) Education Resources Information Centre (ERIC) were searched for articles that investigated the effects of SP-based education on the communication skills of medical, nursing and allied health learners. There were 60 studies included in the review. Only two studies reported direct patient outcomes, one reporting some negative impact, and no studies included an economic analysis. Many studies reported statistically significant third-party ratings of improved communication effectiveness following SP-based education; however, studies were unable to be pooled for meta-analysis because of the outcome collection methods. There were a small number of studies comparing SP with no training at all and there were no differences between communication skills, contradicting the results from studies reporting benefits. Of the 60 studies included for analysis, 54 (90%) met the minimum quality score of 7/11, with four articles (7%) scoring 11/11. SP-based education is widely accepted as a valuable and effective means of teaching communication skills but there is limited evidence of how this translates to patient outcomes and no indication of economic benefit for this

  1. [Simulation exercises, a problem oriented method of learning public health in medical education].

    Science.gov (United States)

    Yano, E; Tamiya, N; Hasegawa, T

    1998-03-01

    Using the case method of learning of American business schools, we introduced "Simulation Exercises (SE)," a problem oriented method of public health education for medical students. With SE, a group of students were given simulated cases of patients or situations (SC), and were asked to assume the role of physicians or other public health workers using their skills and knowledge of public health. Students learn on their own, with the aid of tutors, through discussion, role-play, investigation of literature, and a small field survey. There have been a whole variety of SC covering most of the current topics in public health ranging from mental health, dental health, industrial health, maternal & child health, elderly care, terminal care and international health. Each SC has 5 to 10 questions which stimulate and direct the students' group discussion. Some of the questions do not have a correct answer, but the criteria used to evaluate the students included clarity, consistency, and comprehensiveness of their ideas in addition to the positive commitment to the group discussion. At the end of the week-long group learning, each group demonstrated the results of their discussion. Role play was often used to demonstrate what they learned. As a result, students participated positively and concentrated and enjoyed the learning exercise very much. An anonymous survey shortly after SE showed that more than 80% of students felt a positive change in their rating of public health among the many subjects of study. Tutors also changed their rating of the students after observing their positive attitude and sometimes very creative ideas. In conclusion, we found SE to be useful for practical learning by medical students of public health.

  2. Virtual Patient Simulations for Medical Education: Increasing Clinical Reasoning Skills through Deliberate Practice

    Science.gov (United States)

    McCoy, Lise

    2014-01-01

    Virtual Patient Simulations (VPS) are web-based exercises involving simulated patients in virtual environments. This study investigates the utility of VPS for increasing medical student clinical reasoning skills, collaboration, and engagement. Many studies indicate that VPS provide medical students with essential practice in clinical decision…

  3. Optimized Mooring Line Simulation Using a Hybrid Method Time Domain Scheme

    DEFF Research Database (Denmark)

    Christiansen, Niels Hørbye; Voie, Per Erlend Torbergsen; Høgsberg, Jan

    2014-01-01

    Dynamic analyses of slender marine structures are computationally expensive. Recently it has been shown how a hybrid method which combines FEM models and artificial neural networks (ANN) can be used to reduce the computation time spend on the time domain simulations associated with fatigue analysis...... of mooring lines by two orders of magnitude. The present study shows how an ANN trained to perform nonlinear dynamic response simulation can be optimized using a method known as optimal brain damage (OBD) and thereby be used to rank the importance of all analysis input. Both the training and the optimization...... of the ANN are based on one short time domain simulation sequence generated by a FEM model of the structure. This means that it is possible to evaluate the importance of input parameters based on this single simulation only. The method is tested on a numerical model of mooring lines on a floating offshore...

  4. Method for simulating predictive control of building systems operation in the early stages of building design

    DEFF Research Database (Denmark)

    Petersen, Steffen; Svendsen, Svend

    2011-01-01

    A method for simulating predictive control of building systems operation in the early stages of building design is presented. The method uses building simulation based on weather forecasts to predict whether there is a future heating or cooling requirement. This information enables the thermal...... control systems of the building to respond proactively to keep the operational temperature within the thermal comfort range with the minimum use of energy. The method is implemented in an existing building simulation tool designed to inform decisions in the early stages of building design through...... parametric analysis. This enables building designers to predict the performance of the method and include it as a part of the solution space. The method furthermore facilitates the task of configuring appropriate building systems control schemes in the tool, and it eliminates time consuming manual...

  5. Evaluation of the Use of a Virtual Patient on Student Competence and Confidence in Performing Simulated Clinic Visits.

    Science.gov (United States)

    Taglieri, Catherine A; Crosby, Steven J; Zimmerman, Kristin; Schneider, Tulip; Patel, Dhiren K

    2017-06-01

    Objective. To assess the effect of incorporating virtual patient activities in a pharmacy skills lab on student competence and confidence when conducting real-time comprehensive clinic visits with mock patients. Methods. Students were randomly assigned to a control or intervention group. The control group completed the clinic visit prior to completing virtual patient activities. The intervention group completed the virtual patient activities prior to the clinic visit. Student proficiency was evaluated in the mock lab. All students completed additional exercises with the virtual patient and were subsequently assessed. Student impressions were assessed via a pre- and post-experience survey. Results. Student performance conducting clinic visits was higher in the intervention group compared to the control group. Overall student performance continued to improve in the subsequent module. There was no change in student confidence from pre- to post-experience. Student rating of the ease of use and realistic simulation of the virtual patient increased; however, student rating of the helpfulness of the virtual patient decreased. Despite student rating of the helpfulness of the virtual patient program, student performance improved. Conclusion. Virtual patient activities enhanced student performance during mock clinic visits. Students felt the virtual patient realistically simulated a real patient. Virtual patients may provide additional learning opportunities for students.

  6. The distributed diagonal force decomposition method for parallelizing molecular dynamics simulations.

    Science.gov (United States)

    Borštnik, Urban; Miller, Benjamin T; Brooks, Bernard R; Janežič, Dušanka

    2011-11-15

    Parallelization is an effective way to reduce the computational time needed for molecular dynamics simulations. We describe a new parallelization method, the distributed-diagonal force decomposition method, with which we extend and improve the existing force decomposition methods. Our new method requires less data communication during molecular dynamics simulations than replicated data and current force decomposition methods, increasing the parallel efficiency. It also dynamically load-balances the processors' computational load throughout the simulation. The method is readily implemented in existing molecular dynamics codes and it has been incorporated into the CHARMM program, allowing its immediate use in conjunction with the many molecular dynamics simulation techniques that are already present in the program. We also present the design of the Force Decomposition Machine, a cluster of personal computers and networks that is tailored to running molecular dynamics simulations using the distributed diagonal force decomposition method. The design is expandable and provides various degrees of fault resilience. This approach is easily adaptable to computers with Graphics Processing Units because it is independent of the processor type being used. Copyright © 2011 Wiley Periodicals, Inc.

  7. Transient Response of a Projectile in Gun Launch Simulation Using Lagrangian and Ale Methods

    Directory of Open Access Journals (Sweden)

    A Tabiei

    2016-09-01

    Full Text Available This paper describes the usefulness of Lagrangian and arbitrary Lagrangian/Eulerian (ALE methods in simulating the gun launch dynamics of a generic artillery component subjected to launch simulation in an air gun test. Lagrangian and ALE methods are used to simulate the impact mitigation environment in which the kinetic energy of a projectile is absorbed by the crushing of aluminum honeycomb mitigator. In order to solve the problem due to high impact penetration, a new fluid structure coupling algorithm is developed and implemented in LS-DYNA, a three dimensional FEM code. The fluid structure coupling algorithm used in this paper combined with ALE formulation for the aluminum honeycomb mitigator allows to solve problems for which the contact algorithm in the Lagrangian calculation fails due to high mesh distortion. The numerical method used for the fluid and fluid structure coupling is discussed. A new coupling method is used in order to prevent mesh distortion. Issues related to the effectiveness of these methods in simulating a high degree of distortion of Aluminum honeycomb mitigator with the commonly used material models (metallic honeycomb and crushable foam are discussed. Both computational methods lead to the same prediction for the deceleration of the test projectile and are able to simulate the behavior of the projectile. Good agreement between the test results and the predicted projectile response is achieved via the presented models and the methods employed.

  8. Perspective: authentic patient perspectives in simulations for procedural and surgical skills.

    Science.gov (United States)

    Nestel, Debra; Kneebone, Roger

    2010-05-01

    In this article, the authors consider the role of the patient in simulation-based training and assessment of clinical procedural skills. In recent years, there has been a progressive shift of emphasis from teacher-centered to student-centered education, resulting in a redefinition of approaches to medical education. Traditional models of transmission of information from an expert to a novice have been supplanted by a more student-centered approach. However, medical education is not a matter for teacher and student alone. At the center is always the patient, around whom everything must ultimately rotate. A further shift is occurring. The patient is becoming the focal point of medical teaching and learning. It is argued that this shift is necessary and that simulation in its widest sense can be used to support this process. However, sensitivity to what we are simulating is essential, especially when simulations purport to address patient perspectives. The essay first reviews the history of medical education "centeredness," then outlines ways in which real and simulated patients are currently involved in medical education. Patient-focused simulation (PFS) is described as a means of offering patients' perspectives during the acquisition of clinical procedural and surgical skills. The authors draw on their experiences of developing PFS and preliminary work to "authenticate" simulations from patient perspectives. The essay concludes with speculation on the value of a "complementarity" model that acknowledges the authentic and equal perspectives of patients, students, clinicians, and teachers.

  9. Petascale molecular dynamics simulation using the fast multipole method on K computer

    KAUST Repository

    Ohno, Yousuke

    2014-10-01

    In this paper, we report all-atom simulations of molecular crowding - a result from the full node simulation on the "K computer", which is a 10-PFLOPS supercomputer in Japan. The capability of this machine enables us to perform simulation of crowded cellular environments, which are more realistic compared to conventional MD simulations where proteins are simulated in isolation. Living cells are "crowded" because macromolecules comprise ∼30% of their molecular weight. Recently, the effects of crowded cellular environments on protein stability have been revealed through in-cell NMR spectroscopy. To measure the performance of the "K computer", we performed all-atom classical molecular dynamics simulations of two systems: target proteins in a solvent, and target proteins in an environment of molecular crowders that mimic the conditions of a living cell. Using the full system, we achieved 4.4 PFLOPS during a 520 million-atom simulation with cutoff of 28 Å. Furthermore, we discuss the performance and scaling of fast multipole methods for molecular dynamics simulations on the "K computer", as well as comparisons with Ewald summation methods. © 2014 Elsevier B.V. All rights reserved.

  10. Effect of Advanced Trauma Life Support program on medical interns' performance in simulated trauma patient management

    Directory of Open Access Journals (Sweden)

    Ahmadi Koorosh

    2013-06-01

    Full Text Available 【Abstract】Objective: Since appropriate and time-table methods in trauma care have an important impact on patients’ outcome, we evaluated the effect of Advanced Trauma Life Support (ATLS program on medical interns' performance in simulated trauma patient management. Methods: A descriptive and analytical study before and after the training was conducted on 24 randomly se-lected undergraduate medical interns from Imam Reza Hos-pital in Mashhad, Iran. On the first day, we assessed in-terns' clinical knowledge and their practical skill performance in confronting simulated trauma patients. After 2 days of ATLS training, we performed the same study and evaluated their score again on the fourth day. The two findings, pre-and post- ATLS periods, were compared through SPSS ver-sion 15.0 software. P values less than 0.05 were considered statistically significant. Results: Our findings showed that interns’ ability in all the three tasks improved after the training course. On the fourth day after training, there was a statistically significant increase in interns' clinical knowledge of ATLS procedures, the sequence of procedures and skill performance in trauma situations (P<0.001, P=0.016 and P=0.01 respectively. Conclusion: ATLS course has an important role in increasing clinical knowledge and practical skill performance of trauma care in medical interns. Key words: Advanced Trauma Life Support Care; Knowledge; Inservice training; Wounds and injuries

  11. Comparison of ALE finite element method and adaptive smoothed finite element method for the numerical simulation of friction stir welding

    NARCIS (Netherlands)

    van der Stelt, A.A.; Bor, Teunis Cornelis; Geijselaers, Hubertus J.M.; Quak, W.; Akkerman, Remko; Huetink, Han; Menary, G

    2011-01-01

    In this paper, the material flow around the pin during friction stir welding (FSW) is simulated using a 2D plane strain model. A pin rotates without translation in a disc with elasto-viscoplastic material properties and the outer boundary of the disc is clamped. Two numerical methods are used to

  12. The use of simulated patients in medical education: AMEE Guide No 42.

    Science.gov (United States)

    Cleland, Jennifer A; Abe, Keiko; Rethans, Jan-Joost

    2009-06-01

    Medical training has traditionally depended on patient contact. However, changes in healthcare delivery coupled with concerns about lack of objectivity or standardization of clinical examinations lead to the introduction of the 'simulated patient' (SP). SPs are now used widely for teaching and assessment purposes. SPs are usually, but not necessarily, lay people who are trained to portray a patient with a specific condition in a realistic way, sometimes in a standardized way (where they give a consistent presentation which does not vary from student to student). SPs can be used for teaching and assessment of consultation and clinical/physical examination skills, in simulated teaching environments or in situ. All SPs play roles but SPs have also been used successfully to give feedback and evaluate student performance. Clearly, given this potential level of involvement in medical training, it is critical to recruit, train and use SPs appropriately. We have provided a detailed overview on how to do so, for both teaching and assessment purposes. The contents include: how to monitor and assess SP performance, both in terms of validity and reliability, and in terms of the impact on the SP; and an overview of the methods, staff costs and routine expenses required for recruiting, administrating and training an SP bank, and finally, we provide some intercultural comparisons, a 'snapshot' of the use of SPs in medical education across Europe and Asia, and briefly discuss some of the areas of SP use which require further research.

  13. Priming Patient Safety Through Nursing Handoff Communication: A Simulation Pilot Study.

    Science.gov (United States)

    Groves, Patricia S; Bunch, Jacinda L; Cram, Ellen; Farag, Amany; Manges, Kirstin; Perkhounkova, Yelena; Scott-Cawiezell, Jill

    2017-11-01

    Understanding how safety culture mechanisms affect nursing safety-oriented behavior and thus patient outcomes is critical to developing hospital safety programs. Safety priming refers to communicating safety values intended to activate patient safety goals. Safety priming through nursing handoff communication was tested as a means by which cultural safety values may affect nursing practice. The mixed-methods pilot study setting was an academic medical center's high-fidelity simulation lab. Twenty nurses were randomized into intervention and control groups. The intervention group received a safety priming intervention; all participants were observed for completing appropriate actions in response to patient safety risks embedded in a scenario. Stimulated recall interviews were conducted following simulation completion. Nurses receiving the safety priming intervention performed slightly but non-significantly more safety actions than nurses who did not (60.5% vs. 57.9% of 43 actions). Implications for both research and practice are discussed for interventions targeting routine versus safety goal-directed nursing actions.

  14. Discrete-event computer simulation methods in the optimisation of a physiotherapy clinic.

    Science.gov (United States)

    Villamizar, J R; Coelli, F C; Pereira, W C A; Almeida, R M V R

    2011-03-01

    To develop a computer model to analyse the performance of a standard physiotherapy clinic in the city of Rio de Janeiro, Brazil. The clinic receives an average of 80 patients/day and offers 10 treatment modalities. Details of patient procedures and treatment routines were obtained from direct interviews with clinic staff. Additional data (e.g. arrival time, treatment duration, length of stay) were obtained for 2000 patients from the clinic's computerised records from November 2005 to February 2006. A discrete-event model was used to simulate the clinic's operational routine. The initial model was built to reproduce the actual configuration of the clinic, and five simulation strategies were subsequently implemented, representing changes in the number of patients, human resources of the clinic and the scheduling of patient arrivals. Findings indicated that the actual clinic configuration could accept up to 89 patients/day, with an average length of stay of 119minutes and an average patient waiting time of 3minutes. When the scheduling of patient arrivals was increased to an interval of 6.5minutes, maximum attendance increased to 114 patients/day. For the actual clinic configuration, optimal staffing consisted of three physiotherapists and 12 students. According to the simulation, the same 89 patients could be attended when the infrastructure was decreased to five kinesiotherapy rooms, two cardiotherapy rooms and three global postural reeducation rooms. The model was able to evaluate the capacity of the actual clinic configuration, and additional simulation strategies indicated how the operation of the clinic depended on the main study variables. Copyright © 2010 Chartered Society of Physiotherapy. Published by Elsevier Ltd. All rights reserved.

  15. The effects of a human patient simulator vs. a CD-ROM on performance.

    Science.gov (United States)

    Johnson, Don; Corrigan, Theresa; Gulickson, Gary; Holshouser, Elizabeth; Johnson, Sabine

    2012-10-01

    Military health care personnel need to have skills relative to caring for patients on the battlefield. No studies have compared the two teaching strategies of using the human patient simulator (HPS) and a CD-ROM in caring for combat injuries. The objective of this study was to determine if there were statistically significant differences in HPS and CD-ROM educational strategies relative to caring for patients who have trauma. A pretest/post-test prospective experimental design was used. Anesthesia students were randomly assigned to one of three groups: HPS, CD-ROM, or a control group. A valid and reliable instrument, Combat Performance, was used to evaluate the participant's ability to give care to trauma patients. A repeated analysis of variance and a least significant difference post hoc test were used to analyze the data. The HPS group performed better than the CD-ROM and control groups relative to performance (p = 0.001). There was no difference between the CD-ROM and control group (p = 0.171). We speculate that the HPS group performed better than the CD-ROM group because of the realism. In this study, the HPS method of instruction was a more effective method of teaching than the CD-ROM approach.

  16. Simulation evaluation of statistical properties of methods for indirect and mixed treatment comparisons

    Directory of Open Access Journals (Sweden)

    Song Fujian

    2012-09-01

    Full Text Available Abstract Background Indirect treatment comparison (ITC and mixed treatment comparisons (MTC have been increasingly used in network meta-analyses. This simulation study comprehensively investigated statistical properties and performances of commonly used ITC and MTC methods, including simple ITC (the Bucher method, frequentist and Bayesian MTC methods. Methods A simple network of three sets of two-arm trials with a closed loop was simulated. Different simulation scenarios were based on different number of trials, assumed treatment effects, extent of heterogeneity, bias and inconsistency. The performance of the ITC and MTC methods was measured by the type I error, statistical power, observed bias and mean squared error (MSE. Results When there are no biases in primary studies, all ITC and MTC methods investigated are on average unbiased. Depending on the extent and direction of biases in different sets of studies, ITC and MTC methods may be more or less biased than direct treatment comparisons (DTC. Of the methods investigated, the simple ITC method has the largest mean squared error (MSE. The DTC is superior to the ITC in terms of statistical power and MSE. Under the simulated circumstances in which there are no systematic biases and inconsistencies, the performances of MTC methods are generally better than the performance of the corresponding DTC methods. For inconsistency detection in network meta-analysis, the methods evaluated are on average unbiased. The statistical power of commonly used methods for detecting inconsistency is very low. Conclusions The available methods for indirect and mixed treatment comparisons have different advantages and limitations, depending on whether data analysed satisfies underlying assumptions. To choose the most valid statistical methods for research synthesis, an appropriate assessment of primary studies included in evidence network is required.

  17. A Kernel-Free Particle-Finite Element Method for Hypervelocity Impact Simulation. Chapter 4

    Science.gov (United States)

    Park, Young-Keun; Fahrenthold, Eric P.

    2004-01-01

    An improved hybrid particle-finite element method has been developed for the simulation of hypervelocity impact problems. Unlike alternative methods, the revised formulation computes the density without reference to any kernel or interpolation functions, for either the density or the rate of dilatation. This simplifies the state space model and leads to a significant reduction in computational cost. The improved method introduces internal energy variables as generalized coordinates in a new formulation of the thermomechanical Lagrange equations. Example problems show good agreement with exact solutions in one dimension and good agreement with experimental data in a three dimensional simulation.

  18. Analysis on the influence of supply method on a workstation with the help of dynamic simulation

    Directory of Open Access Journals (Sweden)

    Gavriluță Alin

    2017-01-01

    Full Text Available Considering the need of flexibility in any manufacturing process, the choice of the supply method of an assembly workstation can be a decision with instead influence on its performances. Using dynamic simulation, this article wants to compare the effect on a workstation cycle time of three different supply methods: supply on stock, supply in “Strike Zone” and synchronous supply. This study is part of an extended work that has the aim of compering by 3D layout design and dynamic simulation, different supply methods on an assembly line performances.

  19. Simulating ligand-induced conformational changes in proteins using a mechanical disassembly method.

    Science.gov (United States)

    Cortés, Juan; Le, Duc Thanh; Iehl, Romain; Siméon, Thierry

    2010-08-01

    Simulating protein conformational changes induced or required by the internal diffusion of a ligand is important for the understanding of their interaction mechanisms. Such simulations are challenging for currently available computational methods. In this paper, the problem is formulated as a mechanical disassembly problem where the protein and the ligand are modeled like articulated mechanisms, and an efficient method for computing molecular disassembly paths is described. The method extends recent techniques developed in the framework of robot motion planning. Results illustrating the capacities of the approach are presented on two biologically interesting systems involving ligand-induced conformational changes: lactose permease (LacY), and the beta(2)-adrenergic receptor.

  20. The centricity of presence in scenario-based high fidelity human patient simulation: a model.

    Science.gov (United States)

    Dunnington, Renee M

    2015-01-01

    Enhancing immersive presence has been shown to have influence on learning outcomes in virtual types of simulation. Scenario-based human patient simulation, a mixed reality form, may pose unique challenges for inducing the centricity of presence among participants in simulation. A model for enhancing the centricity of presence in scenario-based human patient simulation is presented here. The model represents a theoretical linkage among the interaction of pedagogical, individual, and group factors that influence the centricity of presence among participants in simulation. Presence may have an important influence on the learning experiences and learning outcomes in scenario-based high fidelity human patient simulation. This report is a follow-up to an article published in 2014 by the author where connections were made to the theoretical basis of presence as articulated by nurse scholars. © The Author(s) 2014.

  1. Comparison of a Local Linearization Algorithm with Standard Numerical Integration Methods for Real-Time Simulation

    DEFF Research Database (Denmark)

    Cook, Gerald; Lin, Ching-Fang

    1980-01-01

    The local linearization algorithm is presented as a possible numerical integration scheme to be used in real-time simulation. A second-order nonlinear example problem is solved using different methods. The local linearization approach is shown to require less computing time and give significant...... improvement in accuracy over the classical second-order integration methods....

  2. Validation of the intrinsic spatial efficiency method for non cylindrical homogeneous sources using MC simulation

    Energy Technology Data Exchange (ETDEWEB)

    Ortiz-Ramírez, Pablo, E-mail: rapeitor@ug.uchile.cl; Ruiz, Andrés [Departamento de Física, Facultad de Ciencias, Universidad de Chile (Chile)

    2016-07-07

    The Monte Carlo simulation of the gamma spectroscopy systems is a common practice in these days. The most popular softwares to do this are MCNP and Geant4 codes. The intrinsic spatial efficiency method is a general and absolute method to determine the absolute efficiency of a spectroscopy system for any extended sources, but this was only demonstrated experimentally for cylindrical sources. Due to the difficulty that the preparation of sources with any shape represents, the simplest way to do this is by the simulation of the spectroscopy system and the source. In this work we present the validation of the intrinsic spatial efficiency method for sources with different geometries and for photons with an energy of 661.65 keV. In the simulation the matrix effects (the auto-attenuation effect) are not considered, therefore these results are only preliminaries. The MC simulation is carried out using the FLUKA code and the absolute efficiency of the detector is determined using two methods: the statistical count of Full Energy Peak (FEP) area (traditional method) and the intrinsic spatial efficiency method. The obtained results show total agreement between the absolute efficiencies determined by the traditional method and the intrinsic spatial efficiency method. The relative bias is lesser than 1% in all cases.

  3. Application of a perturbation method for realistic dynamic simulation of industrial robots

    NARCIS (Netherlands)

    Waiboer, R.R.; Aarts, Ronald G.K.M.; Jonker, Jan B.

    2005-01-01

    This paper presents the application of a perturbation method for the closed-loop dynamic simulation of a rigid-link manipulator with joint friction. In this method the perturbed motion of the manipulator is modelled as a first-order perturbation of the nominal manipulator motion. A non-linear finite

  4. Comparison of Two Methods for Speeding Up Flash Calculations in Compositional Simulations

    DEFF Research Database (Denmark)

    Belkadi, Abdelkrim; Yan, Wei; Michelsen, Michael Locht

    2011-01-01

    Flash calculation is the most time consuming part in compositional reservoir simulations and several approaches have been proposed to speed it up. Two recent approaches proposed in the literature are the shadow region method and the Compositional Space Adaptive Tabulation (CSAT) method. The shado...

  5. Comparison of Two Impact Simulation Methods Used for Nonlinear Vibroimpact Systems with Rigid and Soft Impacts

    Directory of Open Access Journals (Sweden)

    V. A. Bazhenov

    2013-01-01

    shown that both methods are applied and give the coinciding results for system with elastic rigid impact under periodic external loading. Loading curves built by parameter continuation method are confirming this result. Impact simulation by the second method is also fulfilled for vibroimpact system with rigid impact under random external loading. For vibroimpact system with soft impact, the simulation of impact by the second method gives a better result. The application of linear elastic force as contact one is possible too but the use of Hertz's contact force is more preferable. The authors consider that the impact simulation by Hertz contact interaction force gives good results for nonlinear vibroimpact systems with impacts of any kind if all limitations with Hertz's law used are observed.

  6. A New Method to Simulate Free Surface Flows for Viscoelastic Fluid

    Directory of Open Access Journals (Sweden)

    Yu Cao

    2015-01-01

    Full Text Available Free surface flows arise in a variety of engineering applications. To predict the dynamic characteristics of such problems, specific numerical methods are required to accurately capture the shape of free surface. This paper proposed a new method which combined the Arbitrary Lagrangian-Eulerian (ALE technique with the Finite Volume Method (FVM to simulate the time-dependent viscoelastic free surface flows. Based on an open source CFD toolbox called OpenFOAM, we designed an ALE-FVM free surface simulation platform. In the meantime, the die-swell flow had been investigated with our proposed platform to make a further analysis of free surface phenomenon. The results validated the correctness and effectiveness of the proposed method for free surface simulation in both Newtonian fluid and viscoelastic fluid.

  7. A Multi-Projector Calibration Method for Virtual Reality Simulators with Analytically Defined Screens

    Directory of Open Access Journals (Sweden)

    Cristina Portalés

    2017-06-01

    Full Text Available The geometric calibration of projectors is a demanding task, particularly for the industry of virtual reality simulators. Different methods have been developed during the last decades to retrieve the intrinsic and extrinsic parameters of projectors, most of them being based on planar homographies and some requiring an extended calibration process. The aim of our research work is to design a fast and user-friendly method to provide multi-projector calibration on analytically defined screens, where a sample is shown for a virtual reality Formula 1 simulator that has a cylindrical screen. The proposed method results from the combination of surveying, photogrammetry and image processing approaches, and has been designed by considering the spatial restrictions of virtual reality simulators. The method has been validated from a mathematical point of view, and the complete system—which is currently installed in a shopping mall in Spain—has been tested by different users.

  8. Accelerated molecular dynamics and equation-free methods for simulating diffusion in solids.

    Energy Technology Data Exchange (ETDEWEB)

    Deng, Jie; Zimmerman, Jonathan A.; Thompson, Aidan Patrick; Brown, William Michael (Oak Ridge National Laboratories, Oak Ridge, TN); Plimpton, Steven James; Zhou, Xiao Wang; Wagner, Gregory John; Erickson, Lindsay Crowl

    2011-09-01

    Many of the most important and hardest-to-solve problems related to the synthesis, performance, and aging of materials involve diffusion through the material or along surfaces and interfaces. These diffusion processes are driven by motions at the atomic scale, but traditional atomistic simulation methods such as molecular dynamics are limited to very short timescales on the order of the atomic vibration period (less than a picosecond), while macroscale diffusion takes place over timescales many orders of magnitude larger. We have completed an LDRD project with the goal of developing and implementing new simulation tools to overcome this timescale problem. In particular, we have focused on two main classes of methods: accelerated molecular dynamics methods that seek to extend the timescale attainable in atomistic simulations, and so-called 'equation-free' methods that combine a fine scale atomistic description of a system with a slower, coarse scale description in order to project the system forward over long times.

  9. Wargame Simulation Theory and Evaluation Method for Emergency Evacuation of Residents from Urban Waterlogging Disaster Area

    Directory of Open Access Journals (Sweden)

    Peng Chen

    2016-12-01

    Full Text Available Urban waterlogging seriously threatens the safety of urban residents and properties. Wargame simulation research on resident emergency evacuation from waterlogged areas can determine the effectiveness of emergency response plans for high risk events at low cost. Based on wargame theory and emergency evacuation plans, we used a wargame exercise method, incorporating qualitative and quantitative aspects, to build an urban waterlogging disaster emergency shelter using a wargame exercise and evaluation model. The simulation was empirically tested in Daoli District of Harbin. The results showed that the wargame simulation scored 96.40 points, evaluated as good. From the simulation results, wargame simulation of urban waterlogging emergency procedures for disaster response can improve the flexibility and capacity for command, management and decision-making in emergency management departments.

  10. Wargame Simulation Theory and Evaluation Method for Emergency Evacuation of Residents from Urban Waterlogging Disaster Area.

    Science.gov (United States)

    Chen, Peng; Zhang, Jiquan; Sun, Yingyue; Liu, Xiaojing

    2016-12-21

    Urban waterlogging seriously threatens the safety of urban residents and properties. Wargame simulation research on resident emergency evacuation from waterlogged areas can determine the effectiveness of emergency response plans for high risk events at low cost. Based on wargame theory and emergency evacuation plans, we used a wargame exercise method, incorporating qualitative and quantitative aspects, to build an urban waterlogging disaster emergency shelter using a wargame exercise and evaluation model. The simulation was empirically tested in Daoli District of Harbin. The results showed that the wargame simulation scored 96.40 points, evaluated as good. From the simulation results, wargame simulation of urban waterlogging emergency procedures for disaster response can improve the flexibility and capacity for command, management and decision-making in emergency management departments.

  11. analysis of large electromagnetic pulse simulators using the electric field integral equation method in time domain

    CERN Document Server

    Jamali, J; Moini, R; Sadeghi, H

    2002-01-01

    A time-domain approach is presented to calculate electromagnetic fields inside a large Electromagnetic Pulse (EMP) simulator. This type of EMP simulator is used for studying the effect of electromagnetic pulses on electrical apparatus in various structures such as vehicles, a reoplanes, etc. The simulator consists of three planar transmission lines. To solve the problem, we first model the metallic structure of the simulator as a grid of conducting wires. The numerical solution of the governing electric field integral equation is then obtained using the method of moments in time domain. To demonstrate the accuracy of the model, we consider a typical EMP simulator. The comparison of our results with those obtained experimentally in the literature validates the model introduced in this paper.

  12. Multiscale Lattice Boltzmann method for flow simulations in highly heterogenous porous media

    KAUST Repository

    Li, Jun

    2013-01-01

    A lattice Boltzmann method (LBM) for flow simulations in highly heterogeneous porous media at both pore and Darcy scales is proposed in the paper. In the pore scale simulations, flow of two phases (e.g., oil and gas) or two immiscible fluids (e.g., water and oil) are modeled using cohesive or repulsive forces, respectively. The relative permeability can be computed using pore-scale simulations and seamlessly applied for intermediate and Darcy-scale simulations. A multiscale LBM that can reduce the computational complexity of existing LBM and transfer the information between different scales is implemented. The results of coarse-grid, reduced-order, simulations agree very well with the averaged results obtained using fine grid.

  13. Wargame Simulation Theory and Evaluation Method for Emergency Evacuation of Residents from Urban Waterlogging Disaster Area

    Science.gov (United States)

    Chen, Peng; Zhang, Jiquan; Sun, Yingyue; Liu, Xiaojing

    2016-01-01

    Urban waterlogging seriously threatens the safety of urban residents and properties. Wargame simulation research on resident emergency evacuation from waterlogged areas can determine the effectiveness of emergency response plans for high risk events at low cost. Based on wargame theory and emergency evacuation plans, we used a wargame exercise method, incorporating qualitative and quantitative aspects, to build an urban waterlogging disaster emergency shelter using a wargame exercise and evaluation model. The simulation was empirically tested in Daoli District of Harbin. The results showed that the wargame simulation scored 96.40 points, evaluated as good. From the simulation results, wargame simulation of urban waterlogging emergency procedures for disaster response can improve the flexibility and capacity for command, management and decision-making in emergency management departments. PMID:28009805

  14. Apparatus and method for interaction phenomena with world modules in data-flow-based simulation

    Science.gov (United States)

    Xavier, Patrick G [Albuquerque, NM; Gottlieb, Eric J [Corrales, NM; McDonald, Michael J [Albuquerque, NM; Oppel, III, Fred J.

    2006-08-01

    A method and apparatus accommodate interaction phenomenon in a data-flow-based simulation of a system of elements, by establishing meta-modules to simulate system elements and by establishing world modules associated with interaction phenomena. World modules are associated with proxy modules from a group of meta-modules associated with one of the interaction phenomenon. The world modules include a communication world, a sensor world, a mobility world, and a contact world. World modules can be further associated with other world modules if necessary. Interaction phenomenon are simulated in corresponding world modules by accessing member functions in the associated group of proxy modules. Proxy modules can be dynamically allocated at a desired point in the simulation to accommodate the addition of elements in the system of elements such as a system of robots, a system of communication terminals, or a system of vehicles, being simulated.

  15. Simulation evaluation of statistical properties of methods for indirect and mixed treatment comparisons.

    Science.gov (United States)

    Song, Fujian; Clark, Allan; Bachmann, Max O; Maas, Jim

    2012-09-12

    Indirect treatment comparison (ITC) and mixed treatment comparisons (MTC) have been increasingly used in network meta-analyses. This simulation study comprehensively investigated statistical properties and performances of commonly used ITC and MTC methods, including simple ITC (the Bucher method), frequentist and Bayesian MTC methods. A simple network of three sets of two-arm trials with a closed loop was simulated. Different simulation scenarios were based on different number of trials, assumed treatment effects, extent of heterogeneity, bias and inconsistency. The performance of the ITC and MTC methods was measured by the type I error, statistical power, observed bias and mean squared error (MSE). When there are no biases in primary studies, all ITC and MTC methods investigated are on average unbiased. Depending on the extent and direction of biases in different sets of studies, ITC and MTC methods may be more or less biased than direct treatment comparisons (DTC). Of the methods investigated, the simple ITC method has the largest mean squared error (MSE). The DTC is superior to the ITC in terms of statistical power and MSE. Under the simulated circumstances in which there are no systematic biases and inconsistencies, the performances of MTC methods are generally better than the performance of the corresponding DTC methods. For inconsistency detection in network meta-analysis, the methods evaluated are on average unbiased. The statistical power of commonly used methods for detecting inconsistency is very low. The available methods for indirect and mixed treatment comparisons have different advantages and limitations, depending on whether data analysed satisfies underlying assumptions. To choose the most valid statistical methods for research synthesis, an appropriate assessment of primary studies included in evidence network is required.

  16. Pharmacists’ response to anaphylaxis in the community (PRAC): a randomised, simulated patient study of pharmacist practice

    OpenAIRE

    Salter, Sandra M; Delfante, Brock; de Klerk, Sarah; Sanfilippo, Frank M.; Clifford, Rhonda M.

    2014-01-01

    Objective To evaluate how community pharmacists manage patients with anaphylaxis. Design A randomised, cross-sectional, simulated patient study of community pharmacist practice. Setting 300 metropolitan pharmacies located in Perth Australia, randomised to three groups of 100 pharmacies. Each group corresponded to a different epinephrine autoinjector: original EpiPen, new-look EpiPen or Anapen. Participants 300 pharmacies were visited with 271 simulated patient visits included in the final ana...

  17. A novel computer simulation method for simulating the multiscale transduction dynamics of signal proteins

    Science.gov (United States)

    Peter, Emanuel; Dick, Bernhard; Baeurle, Stephan A.

    2012-03-01

    Signal proteins are able to adapt their response to a change in the environment, governing in this way a broad variety of important cellular processes in living systems. While conventional molecular-dynamics (MD) techniques can be used to explore the early signaling pathway of these protein systems at atomistic resolution, the high computational costs limit their usefulness for the elucidation of the multiscale transduction dynamics of most signaling processes, occurring on experimental timescales. To cope with the problem, we present in this paper a novel multiscale-modeling method, based on a combination of the kinetic Monte-Carlo- and MD-technique, and demonstrate its suitability for investigating the signaling behavior of the photoswitch light-oxygen-voltage-2-Jα domain from Avena Sativa (AsLOV2-Jα) and an AsLOV2-Jα-regulated photoactivable Rac1-GTPase (PA-Rac1), recently employed to control the motility of cancer cells through light stimulus. More specifically, we show that their signaling pathways begin with a residual re-arrangement and subsequent H-bond formation of amino acids near to the flavin-mononucleotide chromophore, causing a coupling between β-strands and subsequent detachment of a peripheral α-helix from the AsLOV2-domain. In the case of the PA-Rac1 system we find that this latter process induces the release of the AsLOV2-inhibitor from the switchII-activation site of the GTPase, enabling signal activation through effector-protein binding. These applications demonstrate that our approach reliably reproduces the signaling pathways of complex signal proteins, ranging from nanoseconds up to seconds at affordable computational costs.

  18. Intercomparison of 3D pore-scale flow and solute transport simulation methods

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Xiaofan; Mehmani, Yashar; Perkins, William A.; Pasquali, Andrea; Schönherr, Martin; Kim, Kyungjoo; Perego, Mauro; Parks, Michael L.; Trask, Nathaniel; Balhoff, Matthew T.; Richmond, Marshall C.; Geier, Martin; Krafczyk, Manfred; Luo, Li-Shi; Tartakovsky, Alexandre M.; Scheibe, Timothy D.

    2016-09-01

    Multiple numerical approaches have been developed to simulate porous media fluid flow and solute transport at the pore scale. These include 1) methods that explicitly model the three-dimensional geometry of pore spaces and 2) methods that conceptualize the pore space as a topologically consistent set of stylized pore bodies and pore throats. In previous work we validated a model of the first type, using computational fluid dynamics (CFD) codes employing a standard finite volume method (FVM), against magnetic resonance velocimetry (MRV) measurements of pore-scale velocities. Here we expand that validation to include additional models of the first type based on the lattice Boltzmann method (LBM) and smoothed particle hydrodynamics (SPH), as well as a model of the second type, a pore-network model (PNM). The PNM approach used in the current study was recently improved and demonstrated to accurately simulate solute transport in a two-dimensional experiment. While the PNM approach is computationally much less demanding than direct numerical simulation methods, the effect of conceptualizing complex three-dimensional pore geometries on solute transport in the manner of PNMs has not been fully determined. We apply all four approaches (FVM-based CFD, LBM, SPH and PNM) to simulate pore-scale velocity distributions and (for capable codes) nonreactive solute transport, and intercompare the model results. Comparisons are drawn both in terms of macroscopic variables (e.g., permeability, solute breakthrough curves) and microscopic variables (e.g., local velocities and concentrations). Generally good agreement was achieved among the various approaches, but some differences were observed depending on the model context. The intercomparison work was challenging because of variable capabilities of the codes, and inspired some code enhancements to allow consistent comparison of flow and transport simulations across the full suite of methods. This study provides support for confidence

  19. Methods for simulation-based analysis of fluid-structure interaction.

    Energy Technology Data Exchange (ETDEWEB)

    Barone, Matthew Franklin; Payne, Jeffrey L.

    2005-10-01

    Methods for analysis of fluid-structure interaction using high fidelity simulations are critically reviewed. First, a literature review of modern numerical techniques for simulation of aeroelastic phenomena is presented. The review focuses on methods contained within the arbitrary Lagrangian-Eulerian (ALE) framework for coupling computational fluid dynamics codes to computational structural mechanics codes. The review treats mesh movement algorithms, the role of the geometric conservation law, time advancement schemes, wetted surface interface strategies, and some representative applications. The complexity and computational expense of coupled Navier-Stokes/structural dynamics simulations points to the need for reduced order modeling to facilitate parametric analysis. The proper orthogonal decomposition (POD)/Galerkin projection approach for building a reduced order model (ROM) is presented, along with ideas for extension of the methodology to allow construction of ROMs based on data generated from ALE simulations.

  20. Lattice Boltzmann method used to simulate particle motion in a conduit

    Directory of Open Access Journals (Sweden)

    Dolanský Jindřich

    2017-06-01

    Full Text Available A three-dimensional numerical simulation of particle motion in a pipe with a rough bed is presented. The simulation based on the Lattice Boltzmann Method (LBM employs the hybrid diffuse bounce-back approach to model moving boundaries. The bed of the pipe is formed by stationary spherical particles of the same size as the moving particles. Particle movements are induced by gravitational and hydrodynamic forces. To evaluate the hydrodynamic forces, the Momentum Exchange Algorithm is used. The LBM unified computational frame makes it possible to simulate both the particle motion and the fluid flow and to study mutual interactions of the carrier liquid flow and particles and the particle–bed and particle–particle collisions. The trajectories of simulated and experimental particles are compared. The Particle Tracking method is used to track particle motion. The correctness of the applied approach is assessed.

  1. Multi-Scale Bridge Wash Out Simulation During Tsunami by Using a Particle Method

    Directory of Open Access Journals (Sweden)

    Miyagawa Yoshiya

    2016-01-01

    Full Text Available In 2011, the huge tsunami caused by the great east Japan earthquake devastated many infrastructures in pacific coast of north eastern Japan. Particularly, collapse of bridges caused a traffic disorder and these collapse behaviors led to delay of recovery after the disaster. In this study, the bridge wash away accident is selected as a target issue, and it is represented by a numerical simulation. For this purpose, Smoothed Particle Hydrodynamics (SPH Method, which is one of the pure mesh free methods, is utilized for the rigid body motion simulation. In this study, rigid body motion is introduced for the fluid-rigid interaction behavior during bridge wash away simulation. In the numerical analysis, the upper bridge structure is washed away by receiving an impact fluid force. The wash away simulation of two types of the bridge girder showed good agreement with the real accident on the great east Japan earthquake tsunami.

  2. Comparison of virtual patient simulation with mannequin-based simulation for improving clinical performances in assessing and managing clinical deterioration: randomized controlled trial.

    Science.gov (United States)

    Liaw, Sok Ying; Chan, Sally Wai-Chi; Chen, Fun-Gee; Hooi, Shing Chuan; Siau, Chiang

    2014-09-17

    Virtual patient simulation has grown substantially in health care education. A virtual patient simulation was developed as a refresher training course to reinforce nursing clinical performance in assessing and managing deteriorating patients. The objective of this study was to describe the development of the virtual patient simulation and evaluate its efficacy, by comparing with a conventional mannequin-based simulation, for improving the nursing students' performances in assessing and managing patients with clinical deterioration. A randomized controlled study was conducted with 57 third-year nursing students who were recruited through email. After a baseline evaluation of all participants' clinical performance in a simulated environment, the experimental group received a 2-hour fully automated virtual patient simulation while the control group received 2-hour facilitator-led mannequin-based simulation training. All participants were then re-tested one day (first posttest) and 2.5 months (second posttest) after the intervention. The participants from the experimental group completed a survey to evaluate their learning experiences with the newly developed virtual patient simulation. Compared to their baseline scores, both experimental and control groups demonstrated significant improvements (Pvirtual patient simulation was rated positively. A virtual patient simulation for a refreshing training course on assessing and managing clinical deterioration was developed. Although the randomized controlled study did not show that the virtual patient simulation was superior to mannequin-based simulation, both simulations have demonstrated to be effective refresher learning strategies for improving nursing students' clinical performance. Given the greater resource requirements of mannequin-based simulation, the virtual patient simulation provides a more promising alternative learning strategy to mitigate the decay of clinical performance over time.

  3. A modular method to handle multiple time-dependent quantities in Monte Carlo simulations

    Science.gov (United States)

    Shin, J.; Perl, J.; Schümann, J.; Paganetti, H.; Faddegon, B. A.

    2012-06-01

    A general method for handling time-dependent quantities in Monte Carlo simulations was developed to make such simulations more accessible to the medical community for a wide range of applications in radiotherapy, including fluence and dose calculation. To describe time-dependent changes in the most general way, we developed a grammar of functions that we call ‘Time Features’. When a simulation quantity, such as the position of a geometrical object, an angle, a magnetic field, a current, etc, takes its value from a Time Feature, that quantity varies over time. The operation of time-dependent simulation was separated into distinct parts: the Sequence samples time values either sequentially at equal increments or randomly from a uniform distribution (allowing quantities to vary continuously in time), and then each time-dependent quantity is calculated according to its Time Feature. Due to this modular structure, time-dependent simulations, even in the presence of multiple time-dependent quantities, can be efficiently performed in a single simulation with any given time resolution. This approach has been implemented in TOPAS (TOol for PArticle Simulation), designed to make Monte Carlo simulations with Geant4 more accessible to both clinical and research physicists. To demonstrate the method, three clinical situations were simulated: a variable water column used to verify constancy of the Bragg peak of the Crocker Lab eye treatment facility of the University of California, the double-scattering treatment mode of the passive beam scattering system at Massachusetts General Hospital (MGH), where a spinning range modulator wheel accompanied by beam current modulation produces a spread-out Bragg peak, and the scanning mode at MGH, where time-dependent pulse shape, energy distribution and magnetic fields control Bragg peak positions. Results confirm the clinical applicability of the method.

  4. Simulation of 3D parachute fluid–structure interaction based on nonlinear finite element method and preconditioning finite volume method

    Directory of Open Access Journals (Sweden)

    Fan Yuxin

    2014-12-01

    Full Text Available A fluid–structure interaction method combining a nonlinear finite element algorithm with a preconditioning finite volume method is proposed in this paper to simulate parachute transient dynamics. This method uses a three-dimensional membrane–cable fabric model to represent a parachute system at a highly folded configuration. The large shape change during parachute inflation is computed by the nonlinear Newton–Raphson iteration and the linear system equation is solved by the generalized minimal residual (GMRES method. A membrane wrinkling algorithm is also utilized to evaluate the special uniaxial tension state of membrane elements on the parachute canopy. In order to avoid large time expenses during structural nonlinear iteration, the implicit Hilber–Hughes–Taylor (HHT time integration method is employed. For the fluid dynamic simulations, the Roe and HLLC (Harten–Lax–van Leer contact scheme has been modified and extended to compute flow problems at all speeds. The lower–upper symmetric Gauss–Seidel (LU-SGS approximate factorization is applied to accelerate the numerical convergence speed. Finally, the test model of a highly folded C-9 parachute is simulated at a prescribed speed and the results show similar characteristics compared with experimental results and previous literature.

  5. Comparison of a Material Point Method and a Galerkin Meshfree Method for the Simulation of Cohesive-Frictional Materials

    Directory of Open Access Journals (Sweden)

    Ilaria Iaconeta

    2017-09-01

    Full Text Available The simulation of large deformation problems, involving complex history-dependent constitutive laws, is of paramount importance in several engineering fields. Particular attention has to be paid to the choice of a suitable numerical technique such that reliable results can be obtained. In this paper, a Material Point Method (MPM and a Galerkin Meshfree Method (GMM are presented and verified against classical benchmarks in solid mechanics. The aim is to demonstrate the good behavior of the methods in the simulation of cohesive-frictional materials, both in static and dynamic regimes and in problems dealing with large deformations. The vast majority of MPM techniques in the literatrue are based on some sort of explicit time integration. The techniques proposed in the current work, on the contrary, are based on implicit approaches, which can also be easily adapted to the simulation of static cases. The two methods are presented so as to highlight the similarities to rather than the differences from “standard” Updated Lagrangian (UL approaches commonly employed by the Finite Elements (FE community. Although both methods are able to give a good prediction, it is observed that, under very large deformation of the medium, GMM lacks robustness due to its meshfree natrue, which makes the definition of the meshless shape functions more difficult and expensive than in MPM. On the other hand, the mesh-based MPM is demonstrated to be more robust and reliable for extremely large deformation cases.

  6. Simulation modelling of a patient surge in an emergency department under disaster conditions

    Directory of Open Access Journals (Sweden)

    Muhammet Gul

    2015-10-01

    Full Text Available The efficiency of emergency departments (EDs in handling patient surges during disaster times using the available resources is very important. Many EDs require additional resources to overcome the bottlenecks in emergency systems. The assumption is that EDs consider the option of temporary staff dispatching, among other options, in order to respond to an increased demand or even the hiring temporarily non-hospital medical staff. Discrete event simulation (DES, a well-known simulation method and based on the idea of process modeling, is used for establishing ED operations and management related models. In this study, a DES model is developed to investigate and analyze an ED under normal conditions and an ED in a disaster scenario which takes into consideration an increased influx of disaster victims-patients. This will allow early preparedness of emergency departments in terms of physical and human resources. The studied ED is located in an earthquake zone in Istanbul. The report on Istanbul’s disaster preparedness presented by the Japan International Cooperation Agency (JICA and Istanbul Metropolitan Municipality (IMM, asserts that the district where the ED is located is estimated to have the highest injury rate. Based on real case study information, the study aims to suggest a model on pre-planning of ED resources for disasters. The results indicate that in times of a possible disaster, when the percentage of red patient arrivals exceeds 20% of total patient arrivals, the number of red area nurses and the available space for red area patients will be insufficient for the department to operate effectively. A methodological improvement presented a different distribution function that was tested for service time of the treatment areas. The conclusion is that the Weibull distribution function used in service process of injection room fits the model better than the Gamma distribution function.

  7. The effect of human patient simulation on critical thinking and its predictors in prelicensure nursing students.

    Science.gov (United States)

    Shinnick, Mary Ann; Woo, Mary A

    2013-09-01

    Human patient simulation (HPS) is becoming a popular teaching method in nursing education globally and is believed to enhance both knowledge and critical thinking. While there is evidence that HPS improves knowledge, there is no objective nursing data to support HPS impact on critical thinking. Therefore, we studied knowledge and critical thinking before and after HPS in prelicensure nursing students and attempted to identify the predictors of higher critical thinking scores. Using a one-group, quasi-experimental, pre-test post-test design, 154 prelicensure nursing students (age 25.7± 6.7; gender=87.7% female) from 3 schools were studied at the same point in their curriculum using a high-fidelity simulation. Pre- and post-HPS assessments of knowledge, critical thinking, and self-efficacy were done as well as assessments for demographics and learning style. There was a mean improvement in knowledge scores of 6.5 points (Pcritical thinking scores. A logistic regression with 10 covariates revealed three variables to be predictors of higher critical thinking scores: greater "age" (P=0.01), baseline "knowledge" (P=0.04) and a low self-efficacy score ("not at all confident") in "baseline self-efficacy in managing a patient's fluid levels" (P=.05). This study reveals that gains in knowledge with HPS do not equate to changes in critical thinking. It does expose the variables of older age, higher baseline knowledge and low self-efficacy in "managing a patient's fluid levels" as being predictive of higher critical thinking ability. Further study is warranted to determine the effect of repeated or sequential simulations (dosing) and timing after the HPS experience on critical thinking gains. Copyright © 2012 Elsevier Ltd. All rights reserved.

  8. Solar panel thermal cycling testing by solar simulation and infrared radiation methods

    Science.gov (United States)

    Nuss, H. E.

    1980-01-01

    For the solar panels of the European Space Agency (ESA) satellites OTS/MAROTS and ECS/MARECS the thermal cycling tests were performed by using solar simulation methods. The performance data of two different solar simulators used and the thermal test results are described. The solar simulation thermal cycling tests for the ECS/MARECS solar panels were carried out with the aid of a rotatable multipanel test rig by which simultaneous testing of three solar panels was possible. As an alternative thermal test method, the capability of an infrared radiation method was studied and infrared simulation tests for the ultralight panel and the INTELSAT 5 solar panels were performed. The setup and the characteristics of the infrared radiation unit using a quartz lamp array of approx. 15 sq and LN2-cooled shutter and the thermal test results are presented. The irradiation uniformity, the solar panel temperature distribution, temperature changing rates for both test methods are compared. Results indicate the infrared simulation is an effective solar panel thermal testing method.

  9. Two methods to simulate intrapulpal pressure: effects upon bonding performance of self-etch adhesives.

    Science.gov (United States)

    Feitosa, V P; Gotti, V B; Grohmann, C V; Abuná, G; Correr-Sobrinho, L; Sinhoreti, M A C; Correr, A B

    2014-09-01

    To evaluate the effects of two methods to simulate physiological pulpal pressure on the dentine bonding performance of two all-in-one adhesives and a two-step self-etch silorane-based adhesive by means of microtensile bond strength (μTBS) and nanoleakage surveys. The self-etch adhesives [G-Bond Plus (GB), Adper Easy Bond (EB) and silorane adhesive (SIL)] were applied to flat deep dentine surfaces from extracted human molars. The restorations were constructed using resin composites Filtek Silorane or Filtek Z350 (3M ESPE). After 24 h using the two methods of simulated pulpal pressure or no pulpal pressure (control groups), the bonded teeth were cut into specimens and submitted to μTBS and silver uptake examination. Results were analysed with two-way anova and Tukey's test (P adhesives. No difference between control and pulpal pressure groups was found for SIL and GB. EB led significant drop (P = 0.002) in bond strength under pulpal pressure. Silver impregnation was increased after both methods of simulated pulpal pressure for all adhesives, and it was similar between the simulated pulpal pressure methods. The innovative method to simulate pulpal pressure behaved similarly to the classic one and could be used as an alternative. The HEMA-free one-step and the two-step self-etch adhesives had acceptable resistance against pulpal pressure, unlike the HEMA-rich adhesive. © 2013 International Endodontic Journal. Published by John Wiley & Sons Ltd.

  10. Development of Human Posture Simulation Method for Assessing Posture Angles and Spinal Loads

    Science.gov (United States)

    Lu, Ming-Lun; Waters, Thomas; Werren, Dwight

    2015-01-01

    Video-based posture analysis employing a biomechanical model is gaining a growing popularity for ergonomic assessments. A human posture simulation method of estimating multiple body postural angles and spinal loads from a video record was developed to expedite ergonomic assessments. The method was evaluated by a repeated measures study design with three trunk flexion levels, two lift asymmetry levels, three viewing angles and three trial repetitions as experimental factors. The study comprised two phases evaluating the accuracy of simulating self and other people’s lifting posture via a proxy of a computer-generated humanoid. The mean values of the accuracy of simulating self and humanoid postures were 12° and 15°, respectively. The repeatability of the method for the same lifting condition was excellent (~2°). The least simulation error was associated with side viewing angle. The estimated back compressive force and moment, calculated by a three dimensional biomechanical model, exhibited a range of 5% underestimation. The posture simulation method enables researchers to simultaneously quantify body posture angles and spinal loading variables with accuracy and precision comparable to on-screen posture matching methods. PMID:26361435

  11. Coupling order release methods with autonomous control methods – an assessment of potentials by literature review and discrete event simulation

    Directory of Open Access Journals (Sweden)

    Sebastian Grundstein

    2015-01-01

    Full Text Available Production planning and control faces increasing uncertainty, dynamics and complexity. Autonomous control methods proved themselves as a promising approach for coping with these challenges. However, there is a lack of knowledge regarding the interaction between autonomous control and precedent functions of production planning and control. In particular, up to now previous research has paid no attention to the influence of order release methods on the efficiency of autonomous control methods. Thereby, many researchers over the last decades provided evidence that the order release function has great influence on the logistic objective achievement in conventional production systems. Therefore, this paper examines the influence of order release methods on the efficiency of autonomous control methods by both theoretic evaluation and discrete event simulation. The simulation results indicate an overall high influence. Moreover, the logistic performance differs considerably depending on the implemented order release methods and the combinations of order release methods with autonomous control methods. The findings highlight demand for further research in this field.

  12. Simulation of Powder Layer Deposition in Additive Manufacturing Processes Using the Discrete Element Method

    Energy Technology Data Exchange (ETDEWEB)

    Herbold, E. B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Walton, O. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Homel, M. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-10-26

    This document serves as a final report to a small effort where several improvements were added to a LLNL code GEODYN-­L to develop Discrete Element Method (DEM) algorithms coupled to Lagrangian Finite Element (FE) solvers to investigate powder-­bed formation problems for additive manufacturing. The results from these simulations will be assessed for inclusion as the initial conditions for Direct Metal Laser Sintering (DMLS) simulations performed with ALE3D. The algorithms were written and performed on parallel computing platforms at LLNL. The total funding level was 3-­4 weeks of an FTE split amongst two staff scientists and one post-­doc. The DEM simulations emulated, as much as was feasible, the physical process of depositing a new layer of powder over a bed of existing powder. The DEM simulations utilized truncated size distributions spanning realistic size ranges with a size distribution profile consistent with realistic sample set. A minimum simulation sample size on the order of 40-­particles square by 10-­particles deep was utilized in these scoping studies in order to evaluate the potential effects of size segregation variation with distance displaced in front of a screed blade. A reasonable method for evaluating the problem was developed and validated. Several simulations were performed to show the viability of the approach. Future investigations will focus on running various simulations investigating powder particle sizing and screen geometries.

  13. Multirate Simulations of String Vibrations Including Nonlinear Fret-String Interactions Using the Functional Transformation Method

    Directory of Open Access Journals (Sweden)

    R. Rabenstein

    2004-06-01

    Full Text Available The functional transformation method (FTM is a well-established mathematical method for accurate simulations of multidimensional physical systems from various fields of science, including optics, heat and mass transfer, electrical engineering, and acoustics. This paper applies the FTM to real-time simulations of transversal vibrating strings. First, a physical model of a transversal vibrating lossy and dispersive string is derived. Afterwards, this model is solved with the FTM for two cases: the ideally linearly vibrating string and the string interacting nonlinearly with the frets. It is shown that accurate and stable simulations can be achieved with the discretization of the continuous solution at audio rate. Both simulations can also be performed with a multirate approach with only minor degradations of the simulation accuracy but with preservation of stability. This saves almost 80% of the computational cost for the simulation of a six-string guitar and therefore it is in the range of the computational cost for digital waveguide simulations.

  14. More Than One Way to Debrief: A Critical Review of Healthcare Simulation Debriefing Methods.

    Science.gov (United States)

    Sawyer, Taylor; Eppich, Walter; Brett-Fleegler, Marisa; Grant, Vincent; Cheng, Adam

    2016-06-01

    Debriefing is a critical component in the process of learning through healthcare simulation. This critical review examines the timing, facilitation, conversational structures, and process elements used in healthcare simulation debriefing. Debriefing occurs either after (postevent) or during (within-event) the simulation. The debriefing conversation can be guided by either a facilitator (facilitator-guided) or the simulation participants themselves (self-guided). Postevent facilitator-guided debriefing may incorporate several conversational structures. These conversational structures break the debriefing discussion into a series of 3 or more phases to help organize the debriefing and ensure the conversation proceeds in an orderly manner. Debriefing process elements are an array of techniques to optimize reflective experience and maximize the impact of debriefing. These are divided here into the following 3 categories: essential elements, conversational techniques/educational strategies, and debriefing adjuncts. This review provides both novice and advanced simulation educators with an overview of various methods of conducting healthcare simulation debriefing. Future research will investigate which debriefing methods are best for which contexts and for whom, and also explore how lessons from simulation debriefing translate to debriefing in clinical practice.

  15. cophesim: a comprehensive phenotype simulator for testing novel association methods [version 1; referees: 2 approved

    OpenAIRE

    Ilya Y. Zhbannikov; Konstantin G. Arbeev; Anatoliy I. Yashin

    2017-01-01

    Simulation is important in evaluating novel methods when input data is not easily obtainable or specific assumptions are needed. We present cophesim, a software to add the phenotype to generated genotype data prepared with a genetic simulator. The output of cophesim can be used as a direct input for different genome wide association study tools. cophesim is available from https://bitbucket.org/izhbannikov/cophesim.

  16. cophesim: a comprehensive phenotype simulator for testing novel association methods [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Ilya Y. Zhbannikov

    2017-08-01

    Full Text Available Simulation is important in evaluating novel methods when input data is not easily obtainable or specific assumptions are needed. We present cophesim, a software to add the phenotype to generated genotype data prepared with a genetic simulator. The output of cophesim can be used as a direct input for different genome wide association study tools. cophesim is available from https://bitbucket.org/izhbannikov/cophesim.

  17. Evaluation of Constant Potential Method in Simulating Electric Double-Layer Capacitors

    OpenAIRE

    Wang, Zhenxing; Yang, Yang; Olmsted, David L.; Asta, Mark; Laird, Brian B.

    2014-01-01

    A major challenge in the molecular simulation of electric double layer capacitors (EDLCs) is the choice of an appropriate model for the electrode. Typically, in such simulations the electrode surface is modeled using a uniform fixed charge on each of the electrode atoms, which ignores the electrode response to local charge fluctuations induced by charge fluctuations in the electrolyte. In this work, we evaluate and compare this Fixed Charge Method (FCM) with the more realistic Constant Potent...

  18. Simulation of external flows using a hybrid particle mesh vortex method

    DEFF Research Database (Denmark)

    Spietz, Henrik; Hejlesen, Mads Mølholm; Walther, Jens Honore

    The long-term goal of this project is to develop and apply state-of-the-art simulation software to enable accurate prediction of fluid structure interaction, specifically vortex-induced-vibration and flutter of long-span suspension bridges to avoid error-prone structural designs. In the following...... a hybrid particle mesh vortex method is applied for the simulation of uniform flow past stationary solid obstacles of arbitrary shapes....

  19. Fast and accurate simulations of transmission-line metamaterials using transmission-matrix method

    OpenAIRE

    Ma, Hui Feng; Cui, Tie Jun; Chin, Jessie Yao; Cheng, Qiang

    2009-01-01

    Recently, two-dimensional (2D) periodically L and C loaded transmission-line (TL) networks have been applied to represent metamaterials. The commercial Agilent's Advanced Design System (ADS) is a commonly-used tool to simulate the TL metamaterials. However, it takes a lot of time to set up the TL network and perform numerical simulations using ADS, making the metamaterial analysis inefficient, especially for large-scale TL networks. In this paper, we propose transmission-matrix method (TMM) t...

  20. GPU implementation of the Rosenbluth generation method for static Monte Carlo simulations

    Science.gov (United States)

    Guo, Yachong; Baulin, Vladimir A.

    2017-07-01

    We present parallel version of Rosenbluth Self-Avoiding Walk generation method implemented on Graphics Processing Units (GPUs) using CUDA libraries. The method scales almost linearly with the number of CUDA cores and the method efficiency has only hardware limitations. The method is introduced in two realizations: on a cubic lattice and in real space. We find a good agreement between serial and parallel implementations and consistent results between lattice and real space realizations of the method for linear chain statistics. The developed GPU implementations of Rosenbluth algorithm can be used in Monte Carlo simulations and other computational methods that require large sampling of molecules conformations.

  1. Simulation of Foam Divot Weight on External Tank Utilizing Least Squares and Neural Network Methods

    Science.gov (United States)

    Chamis, Christos C.; Coroneos, Rula M.

    2007-01-01

    Simulation of divot weight in the insulating foam, associated with the external tank of the U.S. space shuttle, has been evaluated using least squares and neural network concepts. The simulation required models based on fundamental considerations that can be used to predict under what conditions voids form, the size of the voids, and subsequent divot ejection mechanisms. The quadratic neural networks were found to be satisfactory for the simulation of foam divot weight in various tests associated with the external tank. Both linear least squares method and the nonlinear neural network predicted identical results.

  2. A Cartesian cut cell method for rarefied flow simulations around moving obstacles

    Energy Technology Data Exchange (ETDEWEB)

    Dechristé, G., E-mail: Guillaume.Dechriste@math.u-bordeaux1.fr [Univ. Bordeaux, IMB, UMR 5251, F-33400 Talence (France); CNRS, IMB, UMR 5251, F-33400 Talence (France); Mieussens, L., E-mail: Luc.Mieussens@math.u-bordeaux1.fr [Univ. Bordeaux, IMB, UMR 5251, F-33400 Talence (France); CNRS, IMB, UMR 5251, F-33400 Talence (France); Bordeaux INP, IMB, UMR 5251, F-33400 Talence (France); INRIA, F-33400 Talence (France)

    2016-06-01

    For accurate simulations of rarefied gas flows around moving obstacles, we propose a cut cell method on Cartesian grids: it allows exact conservation and accurate treatment of boundary conditions. Our approach is designed to treat Cartesian cells and various kinds of cut cells by the same algorithm, with no need to identify the specific shape of each cut cell. This makes the implementation quite simple, and allows a direct extension to 3D problems. Such simulations are also made possible by using an adaptive mesh refinement technique and a hybrid parallel implementation. This is illustrated by several test cases, including a 3D unsteady simulation of the Crookes radiometer.

  3. Comparison of multiple-criteria decision-making methods - results of simulation study

    Directory of Open Access Journals (Sweden)

    Michał Adamczak

    2016-12-01

    Full Text Available Background: Today, both researchers and practitioners have many methods for supporting the decision-making process. Due to the conditions in which supply chains function, the most interesting are multi-criteria methods. The use of sophisticated methods for supporting decisions requires the parameterization and execution of calculations that are often complex. So is it efficient to use sophisticated methods? Methods: The authors of the publication compared two popular multi-criteria decision-making methods: the  Weighted Sum Model (WSM and the Analytic Hierarchy Process (AHP. A simulation study reflects these two decision-making methods. Input data for this study was a set of criteria weights and the value of each in terms of each criterion. Results: The iGrafx Process for Six Sigma simulation software recreated how both multiple-criteria decision-making methods (WSM and AHP function. The result of the simulation was a numerical value defining the preference of each of the alternatives according to the WSM and AHP methods. The alternative producing a result of higher numerical value  was considered preferred, according to the selected method. In the analysis of the results, the relationship between the values of the parameters and the difference in the results presented by both methods was investigated. Statistical methods, including hypothesis testing, were used for this purpose. Conclusions: The simulation study findings prove that the results obtained with the use of two multiple-criteria decision-making methods are very similar. Differences occurred more frequently in lower-value parameters from the "value of each alternative" group and higher-value parameters from the "weight of criteria" group.

  4. Innovative Calibration Method for System Level Simulation Models of Internal Combustion Engines

    Directory of Open Access Journals (Sweden)

    Ivo Prah

    2016-09-01

    Full Text Available The paper outlines a procedure for the computer-controlled calibration of the combined zero-dimensional (0D and one-dimensional (1D thermodynamic simulation model of a turbocharged internal combustion engine (ICE. The main purpose of the calibration is to determine input parameters of the simulation model in such a way as to achieve the smallest difference between the results of the measurements and the results of the numerical simulations with minimum consumption of the computing time. An innovative calibration methodology is based on a novel interaction between optimization methods and physically based methods of the selected ICE sub-systems. Therein physically based methods were used for steering the division of the integral ICE to several sub-models and for determining parameters of selected components considering their governing equations. Innovative multistage interaction between optimization methods and physically based methods allows, unlike the use of well-established methods that rely only on the optimization techniques, for successful calibration of a large number of input parameters with low time consumption. Therefore, the proposed method is suitable for efficient calibration of simulation models of advanced ICEs.

  5. Minimizing the Discrepancy between Simulated and Historical Failures in Turbine Engines: A Simulation-Based Optimization Method

    Directory of Open Access Journals (Sweden)

    Ahmed Kibria

    2015-01-01

    Full Text Available The reliability modeling of a module in a turbine engine requires knowledge of its failure rate, which can be estimated by identifying statistical distributions describing the percentage of failure per component within the turbine module. The correct definition of the failure statistical behavior per component is highly dependent on the engineer skills and may present significant discrepancies with respect to the historical data. There is no formal methodology to approach this problem and a large number of labor hours are spent trying to reduce the discrepancy by manually adjusting the distribution’s parameters. This paper addresses this problem and provides a simulation-based optimization method for the minimization of the discrepancy between the simulated and the historical percentage of failures for turbine engine components. The proposed methodology optimizes the parameter values of the component’s failure statistical distributions within the component’s likelihood confidence bounds. A complete testing of the proposed method is performed on a turbine engine case study. The method can be considered as a decision-making tool for maintenance, repair, and overhaul companies and will potentially reduce the cost of labor associated to finding the appropriate value of the distribution parameters for each component/failure mode in the model and increase the accuracy in the prediction of the mean time to failures (MTTF.

  6. Simulation-based patient flow analysis in an endoscopy unit

    DEFF Research Database (Denmark)

    Koo, Pyung-Hoi; Nielsen, Karl Brian; Jang, Jaejin

    2010-01-01

    , low quality of care and high healthcare cost. This article addresses patient flow problems at a Gastrointestinal endoscopy unit. We attempt to analyze the main factors that contribute to the inefficient patient flow and process bottlenecks and to propose efficient patient scheduling and staff...

  7. A Multilevel Adaptive Reaction-splitting Simulation Method for Stochastic Reaction Networks

    KAUST Repository

    Moraes, Alvaro

    2016-07-07

    In this work, we present a novel multilevel Monte Carlo method for kinetic simulation of stochastic reaction networks characterized by having simultaneously fast and slow reaction channels. To produce efficient simulations, our method adaptively classifies the reactions channels into fast and slow channels. To this end, we first introduce a state-dependent quantity named level of activity of a reaction channel. Then, we propose a low-cost heuristic that allows us to adaptively split the set of reaction channels into two subsets characterized by either a high or a low level of activity. Based on a time-splitting technique, the increments associated with high-activity channels are simulated using the tau-leap method, while those associated with low-activity channels are simulated using an exact method. This path simulation technique is amenable for coupled path generation and a corresponding multilevel Monte Carlo algorithm. To estimate expected values of observables of the system at a prescribed final time, our method bounds the global computational error to be below a prescribed tolerance, TOL, within a given confidence level. This goal is achieved with a computational complexity of order O(TOL-2), the same as with a pathwise-exact method, but with a smaller constant. We also present a novel low-cost control variate technique based on the stochastic time change representation by Kurtz, showing its performance on a numerical example. We present two numerical examples extracted from the literature that show how the reaction-splitting method obtains substantial gains with respect to the standard stochastic simulation algorithm and the multilevel Monte Carlo approach by Anderson and Higham. © 2016 Society for Industrial and Applied Mathematics.

  8. Method for simulating dose reduction in digital mammography using the Anscombe transformation.

    Science.gov (United States)

    Borges, Lucas R; Oliveira, Helder C R de; Nunes, Polyana F; Bakic, Predrag R; Maidment, Andrew D A; Vieira, Marcelo A C

    2016-06-01

    This work proposes an accurate method for simulating dose reduction in digital mammography starting from a clinical image acquired with a standard dose. The method developed in this work consists of scaling a mammogram acquired at the standard radiation dose and adding signal-dependent noise. The algorithm accounts for specific issues relevant in digital mammography images, such as anisotropic noise, spatial variations in pixel gain, and the effect of dose reduction on the detective quantum efficiency. The scaling process takes into account the linearity of the system and the offset of the detector elements. The inserted noise is obtained by acquiring images of a flat-field phantom at the standard radiation dose and at the simulated dose. Using the Anscombe transformation, a relationship is created between the calculated noise mask and the scaled image, resulting in a clinical mammogram with the same noise and gray level characteristics as an image acquired at the lower-radiation dose. The performance of the proposed algorithm was validated using real images acquired with an anthropomorphic breast phantom at four different doses, with five exposures for each dose and 256 nonoverlapping ROIs extracted from each image and with uniform images. The authors simulated lower-dose images and compared these with the real images. The authors evaluated the similarity between the normalized noise power spectrum (NNPS) and power spectrum (PS) of simulated images and real images acquired with the same dose. The maximum relative error was less than 2.5% for every ROI. The added noise was also evaluated by measuring the local variance in the real and simulated images. The relative average error for the local variance was smaller than 1%. A new method is proposed for simulating dose reduction in clinical mammograms. In this method, the dependency between image noise and image signal is addressed using a novel application of the Anscombe transformation. NNPS, PS, and local noise

  9. A Machine Learning Method for the Prediction of Receptor Activation in the Simulation of Synapses

    Science.gov (United States)

    Montes, Jesus; Gomez, Elena; Merchán-Pérez, Angel; DeFelipe, Javier; Peña, Jose-Maria

    2013-01-01

    Chemical synaptic transmission involves the release of a neurotransmitter that diffuses in the extracellular space and interacts with specific receptors located on the postsynaptic membrane. Computer simulation approaches provide fundamental tools for exploring various aspects of the synaptic transmission under different conditions. In particular, Monte Carlo methods can track the stochastic movements of neurotransmitter molecules and their interactions with other discrete molecules, the receptors. However, these methods are computationally expensive, even when used with simplified models, preventing their use in large-scale and multi-scale simulations of complex neuronal systems that may involve large numbers of synaptic connections. We have developed a machine-learning based method that can accurately predict relevant aspects of the behavior of synapses, such as the percentage of open synaptic receptors as a function of time since the release of the neurotransmitter, with considerably lower computational cost compared with the conventional Monte Carlo alternative. The method is designed to learn patterns and general principles from a corpus of previously generated Monte Carlo simulations of synapses covering a wide range of structural and functional characteristics. These patterns are later used as a predictive model of the behavior of synapses under different conditions without the need for additional computationally expensive Monte Carlo simulations. This is performed in five stages: data sampling, fold creation, machine learning, validation and curve fitting. The resulting procedure is accurate, automatic, and it is general enough to predict synapse behavior under experimental conditions that are different to the ones it has been trained on. Since our method efficiently reproduces the results that can be obtained with Monte Carlo simulations at a considerably lower computational cost, it is suitable for the simulation of high numbers of synapses and it is

  10. Benchmark Study of 3D Pore-scale Flow and Solute Transport Simulation Methods

    Science.gov (United States)

    Scheibe, T. D.; Yang, X.; Mehmani, Y.; Perkins, W. A.; Pasquali, A.; Schoenherr, M.; Kim, K.; Perego, M.; Parks, M. L.; Trask, N.; Balhoff, M.; Richmond, M. C.; Geier, M.; Krafczyk, M.; Luo, L. S.; Tartakovsky, A. M.

    2015-12-01

    Multiple numerical approaches have been developed to simulate porous media fluid flow and solute transport at the pore scale. These include 1) methods that explicitly model the three-dimensional geometry of pore spaces and 2) methods that conceptualize the pore space as a topologically consistent set of stylized pore bodies and pore throats. In previous work we validated a model of the first type, using computational fluid dynamics (CFD) codes employing standard finite volume method (FVM), against magnetic resonance velocimetry (MRV) measurements of pore-scale velocities. Here we expand that benchmark study to include additional models of the first type based on the immersed-boundary method (IMB), lattice Boltzmann method (LBM), and smoothed particle hydrodynamics (SPH), as well as a model of the second type, a pore-network model (PNM). While the PNM approach is computationally much less demanding than direct numerical simulation methods, the effect of conceptualizing complex three-dimensional pore geometries in the manner of PNMs has not been fully determined. We apply all five approaches (FVM-based CFD, IMB, LBM, SPH and PNM) to simulate pore-scale velocity distributions and nonreactive solute transport, and intercompare the model results. Comparisons are drawn both in terms of macroscopic variables (e.g., permeability, solute breakthrough curves) and microscopic variables (e.g., local velocities and concentrations). Generally good agreement was achieved among the various approaches, but some differences were observed depending on the model context. The benchmark study was challenging because of variable capabilities of the codes, and inspired some code enhancements to allow consistent comparison of flow and transport simulations across the full suite of methods. This study provides support for confidence in a variety of pore-scale modeling methods, and motivates further development and application of pore-scale simulation methods.

  11. [New methods in training of paediatric emergencies: medical simulation applied to paediatrics].

    Science.gov (United States)

    González Gómez, J M; Chaves Vinagre, J; Ocete Hita, E; Calvo Macías, C

    2008-06-01

    Patient safety constitutes one of the main objectives in health care. Among other recommendations, such as the creation of training centres and the development of patient safety programmes, of great importance is the creation of training programmes for work teams using medical simulation. Medical simulation is defined as "a situation or environment created to allow persons to experience a representation of a real event for the purpose of practice, learning, evaluation or to understand systems or human actions". In this way, abilities can be acquired in serious and uncommon situations with no risk of harm to the patient. This study revises the origins of medical simulation and the different types of simulation are classified. The main simulators currently used in Pediatrics are presented, and the design of a simulation course applied to the training of pediatric emergencies is described, detailing all its different phases. In the first non face-to-face stage, a new concept in medical training known as e-learning is applied. In the second phase, clinical cases are carried out using robotic simulation; this is followed by a debriefing session, which is a key element for acquiring abilities and skills. Lastly, the follow-up phase allows the student to connect with the teachers to consolidate the concepts acquired during the in-person phase. In this model, the aim is to improve scientific-technical abilities in addition to a series of related abilities such as controlling crisis situations, correct leadership of work teams, distribution of tasks, communication among the team members, etc., all of these within the present concept of excellence in care and medical professionalism.

  12. Comparison of two nutritional assessment methods in gastroenterology patients

    OpenAIRE

    Filipović, Branka F; Gajić, Milan; Milinić, Nikola; Milovanović, Branislav; Filipović, Branislav R; Cvetković, Mirjana; Šibalić, Nela

    2010-01-01

    AIM: To investigate and compare efficacy and differences in the nutritional status evaluation of gastroenterology patients by application of two methods: subjective global assessment (SGA) and nutritional risk index (NRI).

  13. Pharmacists’ response to anaphylaxis in the community (PRAC): a randomised, simulated patient study of pharmacist practice

    Science.gov (United States)

    Salter, Sandra M; Delfante, Brock; de Klerk, Sarah; Sanfilippo, Frank M; Clifford, Rhonda M

    2014-01-01

    Objective To evaluate how community pharmacists manage patients with anaphylaxis. Design A randomised, cross-sectional, simulated patient study of community pharmacist practice. Setting 300 metropolitan pharmacies located in Perth Australia, randomised to three groups of 100 pharmacies. Each group corresponded to a different epinephrine autoinjector: original EpiPen, new-look EpiPen or Anapen. Participants 300 pharmacies were visited with 271 simulated patient visits included in the final analysis (88=original EpiPen, 92=new-look EpiPen, 91=Anapen). Outcome measures Primary anaphylaxis preparedness (readiness to treat acute anaphylaxis). Secondary anaphylaxis engagement (willingness to engage the patient in a discussion about their anaphylaxis). Methods Simulated patients approached pharmacists, using a standardised scenario, for assistance with epinephrine autoinjector use and advice about the use of antihistamines in anaphylaxis. Scores for each outcome were obtained based on the number of predefined statements addressed by the pharmacist during the consultation (maximum score=5 for preparedness and 8 for engagement). Results The mean anaphylaxis preparedness score was 2.39 points (SD 1.17). Scores for new-look EpiPen were significantly higher than for original EpiPen and Anapen (2.75 vs 2.38 points, p=0.027; 2.75 vs 2.03 points, pEpiPen were similar to original EpiPen and Anapen (3.11 vs 3.32 points; 3.11 vs 2.90 points, both p=0.42). Engagement was associated with preparedness. For each additional engagement point, preparedness increased by 7% (0.357 points; 95% CI 0.291 to 0.424; p<0.001). Conclusions Pharmacists demonstrated reasonable knowledge of anaphylaxis symptoms and emergency care, but had poor epinephrine autoinjector technique and rarely discussed anaphylaxis action plans. Pharmacists who had a more comprehensive discussion about anaphylaxis with patients, were more prepared for anaphylaxis emergencies. Future research should evaluate the nature and

  14. Use of simulated data sets to evaluate the fidelity of Metagenomicprocessing methods

    Energy Technology Data Exchange (ETDEWEB)

    Mavromatis, Konstantinos; Ivanova, Natalia; Barry, Kerri; Shapiro, Harris; Goltsman, Eugene; McHardy, Alice C.; Rigoutsos, Isidore; Salamov, Asaf; Korzeniewski, Frank; Land, Miriam; Lapidus, Alla; Grigoriev, Igor; Richardson, Paul; Hugenholtz, Philip; Kyrpides, Nikos C.

    2006-12-01

    Metagenomics is a rapidly emerging field of research for studying microbial communities. To evaluate methods presently used to process metagenomic sequences, we constructed three simulated data sets of varying complexity by combining sequencing reads randomly selected from 113 isolate genomes. These data sets were designed to model real metagenomes in terms of complexity and phylogenetic composition. We assembled sampled reads using three commonly used genome assemblers (Phrap, Arachne and JAZZ), and predicted genes using two popular gene finding pipelines (fgenesb and CRITICA/GLIMMER). The phylogenetic origins of the assembled contigs were predicted using one sequence similarity--based (blast hit distribution) and two sequence composition--based (PhyloPythia, oligonucleotide frequencies) binning methods. We explored the effects of the simulated community structure and method combinations on the fidelity of each processing step by comparison to the corresponding isolate genomes. The simulated data sets are available online to facilitate standardized benchmarking of tools for metagenomic analysis.

  15. Analysis of Magnetic Field Intensity and Induced Current under Live Working Based on Charge Simulation Method

    Directory of Open Access Journals (Sweden)

    Luo Yuanxiang

    2015-01-01

    Full Text Available To the problem that safety distance is insufficient for 500 kV substation live working, a magnetic field analysis method for overhead line bus is given based on the charge simulation method. In the method, charge is calculated firstly, and the space field intensity distribution calculation is completed by overlying charge. The space field intensity distribution rule is carried out based on the appropriate analysis, and space field intensity distribution rule of substation is obtained. Then according to the calculation formula of inducing current, the human body induction current under a substation busbar is simulated based on MATLAB. The simulation results have a certain guidance function for actual live working.

  16. Computer Simulation of Nonuniform MTLs via Implicit Wendroff and State-Variable Methods

    Directory of Open Access Journals (Sweden)

    L. Brancik

    2011-04-01

    Full Text Available The paper deals with techniques for a computer simulation of nonuniform multiconductor transmission lines (MTLs based on the implicit Wendroff and the statevariable methods. The techniques fall into a class of finitedifference time-domain (FDTD methods useful to solve various electromagnetic systems. Their basic variants are extended and modified to enable solving both voltage and current distributions along nonuniform MTL’s wires and their sensitivities with respect to lumped and distributed parameters. An experimental error analysis is performed based on the Thomson cable whose analytical solutions are known, and some examples of simulation of both uniform and nonuniform MTLs are presented. Based on the Matlab language programme, CPU times are analyzed to compare efficiency of the methods. Some results for nonlinear MTLs simulation are presented as well.

  17. Finite element method for one-dimensional rill erosion simulation on a curved slope

    Directory of Open Access Journals (Sweden)

    Lijuan Yan

    2015-03-01

    Full Text Available Rill erosion models are important to hillslope soil erosion prediction and to land use planning. The development of rill erosion models and their use has become increasingly of great concern. The purpose of this research was to develop mathematic models with computer simulation procedures to simulate and predict rill erosion. The finite element method is known as an efficient tool in many other applications than in rill soil erosion. In this study, the hydrodynamic and sediment continuity model equations for a rill erosion system were solved by the Galerkin finite element method and Visual C++ procedures. The simulated results are compared with the data for spatially and temporally measured processes for rill erosion under different conditions. The results indicate that the one-dimensional linear finite element method produced excellent predictions of rill erosion processes. Therefore, this study supplies a tool for further development of a dynamic soil erosion prediction model.

  18. Simulation of cryolipolysis as a novel method for noninvasive fat layer reduction.

    Science.gov (United States)

    Majdabadi, Abbas; Abazari, Mohammad

    2016-12-20

    Regarding previous problems in conventional liposuction methods, the need for development of new fat removal operations was appreciated. In this study we are going to simulate one of the novel methods, cryolipolysis, aimed to tackle those drawbacks. We think that simulation of clinical procedures contributes considerably in efficacious performance of the operations. To do this we have attempted to simulate temperature distribution in a sample fat of the human body. Using Abaqus software we have presented the graphical display of temperature-time variations within the medium. Findings of our simulation indicate that tissue temperature decreases after cold exposure of about 30 min. It can be seen that the minimum temperature of tissue occurs in shallow layers of the sample and the temperature in deeper layers of the sample remains nearly unchanged. It is clear that cold exposure time of more than the specific time (t > 30 min) does not result in considerable changes. Numerous clinical studies have proved the efficacy of cryolipolysis. This noninvasive technique has eliminated some of drawbacks of conventional methods. Findings of our simulation clearly prove the efficiency of this method, especially for superficial fat layers.

  19. Patient-specific 3D simulation of cyclic CSF flow at the craniocervical region.

    Science.gov (United States)

    Rutkowska, G; Haughton, V; Linge, S; Mardal, K-A

    2012-10-01

    Flow simulations in patient-specific models of the subarachnoid space characterize CSF flow in more detail than MR flow imaging. We extended previous simulation studies by including cyclic CSF flow and patient-specific models in multiple patients with Chiari I. We compared simulation results with MR flow measurements. Volumetric high resolution image sets acquired in 7 patients with Chiari I, 3 patients who had previous craniovertebral decompression, and 3 controls were segmented and converted to mathematical models of the subarachnoid space. CSF flow velocities and pressures were calculated with high spatial and temporal resolution during simulated oscillatory flow in each model with the Navier-Stokes equations. Pressures, velocities, and bidirectional flow were compared in the groups (with Student t test). Peak velocities in the simulations were compared with peak velocities measured in vivo with PCMR. Flow visualization for patients and volunteers demonstrated nonuniform reversing patterns resembling those observed with PCMR. Velocities in the 13 subjects were greater between C2 and C5 than in the foramen magnum. Chiari patients had significantly greater peak systolic and diastolic velocities, synchronous bidirectional flow, and pressure gradients than controls. Peak velocities measured in PCMR correlated significantly (P = .003; regression analysis) despite differences between them. In simulations of CSF, patients with Chiari I had significantly greater peak systolic and diastolic velocities, synchronous bidirectional flow, and pressure gradients than controls.

  20. [Background : the literature suggests that simulation is an effective strategy to meet the learning needs of nursing students. Traditionally, simulation learning for nursing students takes place at nursing schools ; at a distance from the clinical setting, patients, and the interprofessional team.Aim : the objective of this pilot project is to explore the experiences of Francophone nursing students following their participation in an interprofessional simulation in a hospital setting during their third year clinical placements.Method : a case study using Yin's (2003) approach was used to explore this phenomenon through focus groups and individual interviews.Results : thirteen people participated in three simulation sessions that each included two scenarios. Content analysis of the focus groups revealed four themes : 1) the need for a realistic, but safe environment ; 2) simulation helps to build self-confidence ; 3) simulation improves knowledge of the role of the nurse ; and 4) simulation improves knowledge of teamwork. Two themes emerged from individual interviews : 1) the knowledge and skills acquired during the simulation were retained over time ; and 2) perceptions of the effects on the quality and safety of patient care.Conclusion].

    Science.gov (United States)

    Lalonde, Michelle; Malouin-Benoit, Marie-Christine; Gagnon, Elizabeth; Michon, Alain; Maisonneuve, Monique; Desroches, Janie

    2018-02-02

    the literature suggests that simulation is an effective strategy to meet the learning needs of nursing students. Traditionally, simulation learning for nursing students takes place at nursing schools ; at a distance from the clinical setting, patients, and the interprofessional team. the objective of this pilot project is to explore the experiences of Francophone nursing students following their participation in an interprofessional simulation in a hospital setting during their third year clinical placements. a case study using Yin's (2003) approach was used to explore this phenomenon through focus groups and individual interviews. thirteen people participated in three simulation sessions that each included two scenarios. Content analysis of the focus groups revealed four themes : 1) the need for a realistic, but safe environment ; 2) simulation helps to build self-confidence ; 3) simulation improves knowledge of the role of the nurse ; and 4) simulation improves knowledge of teamwork. Two themes emerged from individual interviews : 1) the knowledge and skills acquired during the simulation were retained over time ; and 2) perceptions of the effects on the quality and safety of patient care. the use of simulation could be effective for the development of knowledge of nursing role, teamwork, and self-confidence.

  1. Nonlinear simulation of arch dam cracking with mixed finite element method

    Directory of Open Access Journals (Sweden)

    Ren Hao

    2008-06-01

    Full Text Available This paper proposes a new, simple and efficient method for nonlinear simulation of arch dam cracking from the construction period to the operation period, which takes into account the arch dam construction process and temperature loads. In the calculation mesh, the contact surface of pair nodes is located at places on the arch dam where cracking is possible. A new effective iterative method, the mixed finite element method for friction-contact problems, is improved and used for nonlinear simulation of the cracking process. The forces acting on the structure are divided into two parts: external forces and contact forces. The displacement of the structure is chosen as the basic variable and the nodal contact force in the possible contact region of the local coordinate system is chosen as the iterative variable, so that the nonlinear iterative process is only limited within the possible contact surface and is much more economical. This method was used to simulate the cracking process of the Shuanghe Arch Dam in Southwest China. In order to prove the validity and accuracy of this method and to study the effect of thermal stress on arch dam cracking, three schemes were designed for calculation. Numerical results agree with actual measured data, proving that it is feasible to use this method to simulate the entire process of nonlinear arch dam cracking.

  2. Shielding analyses of an AB-BNCT facility using Monte Carlo simulations and simplified methods

    Directory of Open Access Journals (Sweden)

    Lai Bo-Lun

    2017-01-01

    Full Text Available Accurate Monte Carlo simulations and simplified methods were used to investigate the shielding requirements of a hypothetical accelerator-based boron neutron capture therapy (AB-BNCT facility that included an accelerator room and a patient treatment room. The epithermal neutron beam for BNCT purpose was generated by coupling a neutron production target with a specially designed beam shaping assembly (BSA, which was embedded in the partition wall between the two rooms. Neutrons were produced from a beryllium target bombarded by 1-mA 30-MeV protons. The MCNP6-generated surface sources around all the exterior surfaces of the BSA were established to facilitate repeated Monte Carlo shielding calculations. In addition, three simplified models based on a point-source line-of-sight approximation were developed and their predictions were compared with the reference Monte Carlo results. The comparison determined which model resulted in better dose estimation, forming the basis of future design activities for the first ABBNCT facility in Taiwan.

  3. Shielding analyses of an AB-BNCT facility using Monte Carlo simulations and simplified methods

    Science.gov (United States)

    Lai, Bo-Lun; Sheu, Rong-Jiun

    2017-09-01

    Accurate Monte Carlo simulations and simplified methods were used to investigate the shielding requirements of a hypothetical accelerator-based boron neutron capture therapy (AB-BNCT) facility that included an accelerator room and a patient treatment room. The epithermal neutron beam for BNCT purpose was generated by coupling a neutron production target with a specially designed beam shaping assembly (BSA), which was embedded in the partition wall between the two rooms. Neutrons were produced from a beryllium target bombarded by 1-mA 30-MeV protons. The MCNP6-generated surface sources around all the exterior surfaces of the BSA were established to facilitate repeated Monte Carlo shielding calculations. In addition, three simplified models based on a point-source line-of-sight approximation were developed and their predictions were compared with the reference Monte Carlo results. The comparison determined which model resulted in better dose estimation, forming the basis of future design activities for the first ABBNCT facility in Taiwan.

  4. Development and Validation of Simulated Virtual Patients to Impart Early Clinical Exposure in Endocrine Physiology

    Science.gov (United States)

    Gupta, Akriti; Singh, Satendra; Khaliq, Farah; Dhaliwal, Upreet; Madhu, S. V.

    2018-01-01

    In the country presently, preclinical medical students are not routinely exposed to real patients. Thus, when they start clinical postings, they are found to have poor clinical reasoning skills. Simulated virtual patients (SVPs) can improve clinical skills without endangering real patients. This pilot study describes the development of two SVPs in…

  5. Simulation of anisotropic diffusion by means of a diffusion velocity method

    CERN Document Server

    Beaudoin, A; Rivoalen, E

    2003-01-01

    An alternative method to the Particle Strength Exchange method for solving the advection-diffusion equation in the general case of a non-isotropic and non-uniform diffusion is proposed. This method is an extension of the diffusion velocity method. It is shown that this extension is quite straightforward due to the explicit use of the diffusion flux in the expression of the diffusion velocity. This approach is used to simulate pollutant transport in groundwater and the results are compared to those of the PSE method presented in an earlier study by Zimmermann et al.

  6. Experimental results and Monte Carlo simulations of a landmine localization device using the neutron backscattering method

    CERN Document Server

    Datema, C P; Eijk, C W E

    2002-01-01

    Experiments were carried out to investigate the possible use of neutron backscattering for the detection of landmines buried in the soil. Several landmines, buried in a sand-pit, were positively identified. A series of Monte Carlo simulations were performed to study the complexity of the neutron backscattering process and to optimize the geometry of a future prototype. The results of these simulations indicate that this method shows great potential for the detection of non-metallic landmines (with a plastic casing), for which so far no reliable method has been found.

  7. Parameter Studies, time-dependent simulations and design with automated Cartesian methods

    Science.gov (United States)

    Aftosmis, Michael

    2005-01-01

    Over the past decade, NASA has made a substantial investment in developing adaptive Cartesian grid methods for aerodynamic simulation. Cartesian-based methods played a key role in both the Space Shuttle Accident Investigation and in NASA's return to flight activities. The talk will provide an overview of recent technological developments focusing on the generation of large-scale aerodynamic databases, automated CAD-based design, and time-dependent simulations with of bodies in relative motion. Automation, scalability and robustness underly all of these applications and research in each of these topics will be presented.

  8. An innovative exercise method to simulate orbital EVA work - Applications to PLSS automatic controls

    Science.gov (United States)

    Lantz, Renee; Vykukal, H.; Webbon, Bruce

    1987-01-01

    An exercise method has been proposed which may satisfy the current need for a laboratory simulation representative of muscular, cardiovascular, respiratory, and thermoregulatory responses to work during orbital extravehicular activity (EVA). The simulation incorporates arm crank ergometry with a unique body support mechanism that allows all body position stabilization forces to be reacted at the feet. By instituting this exercise method in laboratory experimentation, an advanced portable life support system (PLSS) thermoregulatory control system can be designed to more accurately reflect the specific work requirements of orbital EVA.

  9. A Lagrangian finite element method for the simulation of flow of non-newtonian liquids

    DEFF Research Database (Denmark)

    Hassager, Ole; Bisgaard, C

    1983-01-01

    A Lagrangian method for the simulation of flow of non-Newtonian liquids is implemented. The fluid mechanical equations are formulated in the form of a variational principle, and a discretization is performed by finite elements. The method is applied to the slow of a contravariant convected Maxwell...... liquid around a sphere moving axially in a cylinder. The simulations show that the friction factor for a sphere in a narrow cylinder is a rapidly decreasing function of the Deborah number, while the friction factor for a sphere in a very wide cylinder is not significantly affected by fluid elasticity...

  10. Use of simulated patients to develop communication skills in nursing education: An integrative review.

    Science.gov (United States)

    MacLean, Sharon; Kelly, Michelle; Geddes, Fiona; Della, Phillip

    2017-01-01

    Registered nurses are expected to communicate effectively with patients. To improve on this skill education programmes in both hospital and tertiary settings are increasingly turning to simulation modalities when training undergraduate and registered nurses. The roles simulated patients (SPs) assume can vary according to training purposes and approach. The first aim is to analyse how SPs are used in nursing education to develop communication skills. The second aim is to evaluate the evidence that is available to support the efficacy of using SPs for training nurses in communication skills and finally to review the SP recruitment and training procedure. An Integrative review. A search was conducted on CINAHL, Psych-info, PubMed, Google Scholar, Scopus, Ovid, Medline, and ProQuest databases. Keywords and inclusion/exclusion criteria were determined and applied to the search strategy. The integrative review included Nineteen studies from 2006-2016. Critical Appraisal Skills Program (CASP) method of evaluation was utilised. Emergent themes were extracted with similar and divergent perspectives. Analysis identified seven clinical contexts for communication skills training (CST) and two SP roles from the eighteen studies. SPs were either directly involved in the teaching of communication (active role) or used in the evaluation of the effectiveness of a communication skills program (passive role). A majority of studies utilised faculty-designed measurement instruments. The evidence presented in the 19 articles indicates that the use of SPs to teach nurse-patient communication skills targets more challenging clinical interactions. Engaging SPs in both CST program facilitation and course evaluation provides nurse educators with a strong foundation to develop further pedagogical and research capacity. Expanding the utilisation of SPs to augment nurses' communication skills and ability to engage with patients in a broader range of clinical contexts with increased

  11. A method to simulate grictional heating at defects in ultrasonic infrared thermography

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Won Jar; Choi, Man Yong; Park, Jeong Hak [Center for Safety Measurement, KRISS, Daejeon(Korea, Republic of)

    2015-12-15

    Ultrasonic infrared thermography is an active thermography methods. In this method, mechanical energy is introduced to a structure, it is converted into heat energy at the defects, and an infrared camera detects the heat for inspection. The heat generation mechanisms are dependent on many factors such as structure characteristics, defect type, excitation method and contact condition, which make it difficult to predict heat distribution in ultrasonic infrared thermography. In this paper, a method to simulate frictional heating, known to be one of the main heat generation mechanisms at the closed defects in metal structures, is proposed for ultrasonic infrared thermography. This method uses linear vibration analysis results without considering the contact boundary condition at the defect so that it is intuitive and simple to implement. Its advantages and disadvantages are also discussed. The simulation results show good agreement with the modal analysis and experiment result.

  12. Hydrodynamic Force Evaluation by Momentum Exchange Method in Lattice Boltzmann Simulations

    Directory of Open Access Journals (Sweden)

    Binghai Wen

    2015-12-01

    Full Text Available As a native scheme to evaluate hydrodynamic force in the lattice Boltzmann method, the momentum exchange method has some excellent features, such as simplicity, accuracy, high efficiency and easy parallelization. Especially, it is independent of boundary geometry, preventing from solving the Navier–Stokes equations on complex boundary geometries in the boundary-integral methods. We review the origination and main developments of the momentum exchange method in lattice Boltzmann simulations. Then several practical techniques to fill newborn fluid nodes are discussed for the simulations of fluid-structure interactions. Finally, some representative applications show the wide applicability of the momentum exchange method, such as movements of rigid particles, interactions of deformation particles, particle suspensions in turbulent flow and multiphase flow, etc.

  13. A novel energy conversion based method for velocity correction in molecular dynamics simulations

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Hanhui [School of Aeronautics and Astronautics, Zhejiang University, Hangzhou 310027 (China); Collaborative Innovation Center of Advanced Aero-Engine, Hangzhou 310027 (China); Liu, Ningning [School of Aeronautics and Astronautics, Zhejiang University, Hangzhou 310027 (China); Ku, Xiaoke, E-mail: xiaokeku@zju.edu.cn [School of Aeronautics and Astronautics, Zhejiang University, Hangzhou 310027 (China); Fan, Jianren [State Key Laboratory of Clean Energy Utilization, Zhejiang University, Hangzhou 310027 (China)

    2017-05-01

    Molecular dynamics (MD) simulation has become an important tool for studying micro- or nano-scale dynamics and the statistical properties of fluids and solids. In MD simulations, there are mainly two approaches: equilibrium and non-equilibrium molecular dynamics (EMD and NEMD). In this paper, a new energy conversion based correction (ECBC) method for MD is developed. Unlike the traditional systematic correction based on macroscopic parameters, the ECBC method is developed strictly based on the physical interaction processes between the pair of molecules or atoms. The developed ECBC method can apply to EMD and NEMD directly. While using MD with this method, the difference between the EMD and NEMD is eliminated, and no macroscopic parameters such as external imposed potentials or coefficients are needed. With this method, many limits of using MD are lifted. The application scope of MD is greatly extended.

  14. Simulation on the Self-Compacting Concrete by an Enhanced Lagrangian Particle Method

    Directory of Open Access Journals (Sweden)

    Jun Wu

    2016-01-01

    Full Text Available The industry has embraced self-compacting concrete (SCC to overcome deficiencies related to consolidation, improve productivity, and enhance safety and quality. Due to the large deformation at the flowing process of SCC, an enhanced Lagrangian particle-based method, Smoothed Particles Hydrodynamics (SPH method, though first developed to study astrophysics problems, with its exceptional advantages in solving problems involving fragmentation, coalescence, and violent free surface deformation, is developed in this study to simulate the flow of SCC as a non-Newtonian fluid to achieve stable results with satisfactory convergence properties. Navier-Stokes equations and incompressible mass conservation equations are solved as basics. Cross rheological model is used to simulate the shear stress and strain relationship of SCC. Mirror particle method is used for wall boundaries. The improved SPH method is tested by a typical 2D slump flow problem and also applied to L-box test. The capability and results obtained from this method are discussed.

  15. Numerical study of MPS method with large eddy simulation for fluid solid coupling problem

    Science.gov (United States)

    YANG, Chao; ZHANG, Huaixin; YAO, Huilan

    2017-02-01

    The Moving-Particle Semi-implicit method (MPS) is a kind of meshless Lagrangian calculation method. This method uses particles instead of mesh. In the pretreatment it works simply and conveniently and has high computational efficiency. In practical engineering, many of fluid problems are turbulent flows. Large eddy simulation is a major means of studying turbulence. Fluid-structure coupling is an independent branch of mechanics combined with fluid dynamics and solid mechanics, which is the hot and difficult area of research in many fields at present. In this paper, for the numerical simulation of turbulent flow with interaction of fluid-structure, the modified MPS-LES method is applied in two dimensional dam-break problem. It proves that MPS-LES method can be extended on solving the fluid-solid coupled problem.

  16. A fast exact simulation method for a class of Markov jump processes.

    Science.gov (United States)

    Li, Yao; Hu, Lili

    2015-11-14

    A new method of the stochastic simulation algorithm (SSA), named the Hashing-Leaping method (HLM), for exact simulations of a class of Markov jump processes, is presented in this paper. The HLM has a conditional constant computational cost per event, which is independent of the number of exponential clocks in the Markov process. The main idea of the HLM is to repeatedly implement a hash-table-like bucket sort algorithm for all times of occurrence covered by a time step with length τ. This paper serves as an introduction to this new SSA method. We introduce the method, demonstrate its implementation, analyze its properties, and compare its performance with three other commonly used SSA methods in four examples. Our performance tests and CPU operation statistics show certain advantages of the HLM for large scale problems.

  17. A fast exact simulation method for a class of Markov jump processes

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yao, E-mail: yaoli@math.umass.edu [Department of Mathematics and Statistics, University of Massachusetts Amherst, Amherst, Massachusetts 10003 (United States); Hu, Lili, E-mail: lilyhu86@gmail.com [School of Mathematics, Georgia Institute of Technology, Atlanta, Georgia 30332 (United States)

    2015-11-14

    A new method of the stochastic simulation algorithm (SSA), named the Hashing-Leaping method (HLM), for exact simulations of a class of Markov jump processes, is presented in this paper. The HLM has a conditional constant computational cost per event, which is independent of the number of exponential clocks in the Markov process. The main idea of the HLM is to repeatedly implement a hash-table-like bucket sort algorithm for all times of occurrence covered by a time step with length τ. This paper serves as an introduction to this new SSA method. We introduce the method, demonstrate its implementation, analyze its properties, and compare its performance with three other commonly used SSA methods in four examples. Our performance tests and CPU operation statistics show certain advantages of the HLM for large scale problems.

  18. Study of Monte Carlo Simulation Method for Methane Phase Diagram Prediction using Two Different Potential Models

    KAUST Repository

    Kadoura, Ahmad

    2011-06-06

    Lennard‐Jones (L‐J) and Buckingham exponential‐6 (exp‐6) potential models were used to produce isotherms for methane at temperatures below and above critical one. Molecular simulation approach, particularly Monte Carlo simulations, were employed to create these isotherms working with both canonical and Gibbs ensembles. Experiments in canonical ensemble with each model were conducted to estimate pressures at a range of temperatures above methane critical temperature. Results were collected and compared to experimental data existing in literature; both models showed an elegant agreement with the experimental data. In parallel, experiments below critical temperature were run in Gibbs ensemble using L‐J model only. Upon comparing results with experimental ones, a good fit was obtained with small deviations. The work was further developed by adding some statistical studies in order to achieve better understanding and interpretation to the estimated quantities by the simulation. Methane phase diagrams were successfully reproduced by an efficient molecular simulation technique with different potential models. This relatively simple demonstration shows how powerful molecular simulation methods could be, hence further applications on more complicated systems are considered. Prediction of phase behavior of elemental sulfur in sour natural gases has been an interesting and challenging field in oil and gas industry. Determination of elemental sulfur solubility conditions helps avoiding all kinds of problems caused by its dissolution in gas production and transportation processes. For this purpose, further enhancement to the methods used is to be considered in order to successfully simulate elemental sulfur phase behavior in sour natural gases mixtures.

  19. Simulation of the Ill-Posed Problem of Reinforced Concrete Corrosion Detection Using Boundary Element Method

    Directory of Open Access Journals (Sweden)

    Syarizal Fonna

    2016-01-01

    Full Text Available Many studies have suggested that the corrosion detection of reinforced concrete (RC based on electrical potential on concrete surface was an ill-posed problem, and thus it may present an inaccurate interpretation of corrosion. However, it is difficult to prove the ill-posed problem of the RC corrosion detection by experiment. One promising technique is using a numerical method. The objective of this study is to simulate the ill-posed problem of RC corrosion detection based on electrical potential on a concrete surface using the Boundary Element Method (BEM. BEM simulates electrical potential within a concrete domain. In order to simulate the electrical potential, the domain is assumed to be governed by Laplace’s equation. The boundary conditions for the corrosion area and the noncorrosion area of rebar were selected from its polarization curve. A rectangular reinforced concrete model with a single rebar was chosen to be simulated using BEM. The numerical simulation results using BEM showed that the same electrical potential distribution on the concrete surface could be generated from different combinations of parameters. Corresponding to such a phenomenon, this problem can be categorized as an ill-posed problem since it has many solutions. Therefore, BEM successfully simulates the ill-posed problem of reinforced concrete corrosion detection.

  20. Time-domain hybrid method for simulating large amplitude motions of ships advancing in waves

    Directory of Open Access Journals (Sweden)

    Shukui Liu

    2011-03-01

    Full Text Available Typical results obtained by a newly developed, nonlinear time domain hybrid method for simulating large amplitude motions of ships advancing with constant forward speed in waves are presented. The method is hybrid in the way of combining a time-domain transient Green function method and a Rankine source method. The present approach employs a simple double integration algorithm with respect to time to simulate the free-surface boundary condition. During the simulation, the diffraction and radiation forces are computed by pressure integration over the mean wetted surface, whereas the incident wave and hydrostatic restoring forces/moments are calculated on the instantaneously wetted surface of the hull. Typical numerical results of application of the method to the seakeeping performance of a standard containership, namely the ITTC S175, are herein presented. Comparisons have been made between the results from the present method, the frequency domain 3D panel method (NEWDRIFT of NTUA-SDL and available experimental data and good agreement has been observed for all studied cases between the results of the present method and comparable other data.

  1. Predicting fluid responsiveness in whom? A simulated example of patient spectrum influencing the receiver operating characteristics curve.

    Science.gov (United States)

    Høiseth, Lars Øivind; Hagemo, Jostein S

    2017-04-21

    The influence of patient spectrum on the sensitivities and specificities of diagnostic methods has been termed spectrum bias or spectrum effect. Receiver operating characteristics curves are often used to assess the ability of diagnostic methods to predict fluid responsiveness. As a receiver operating characteristics curve is a presentation of sensitivity and specificity, the purpose of the present manuscript was to explore if patient spectrum could affect areas under receiver operating characteristics curves and their gray zones. Relationships between stroke volume variation and change in stroke volume in two different patient populations using simulated data. Simulated patient populations with stroke volume variation values between 5 and 15 or 3 and 25% had median (2.5th-97.5th percentiles) areas under receiver operating characteristics curves of 0.79 (0.65-0.90) and 0.93 (0.85-0.99), respectively. The gray zones indicating range of diagnostic uncertainty were also affected. The patient spectrum can affect common statistics from receiver operating characteristics curves, indicating the need for considering patient spectrum when evaluating the abilities of different methods to predict fluid responsiveness.

  2. Simulation of granular and gas-solid flows using discrete element method

    Science.gov (United States)

    Boyalakuntla, Dhanunjay S.

    2003-10-01

    In recent years there has been increased research activity in the experimental and numerical study of gas-solid flows. Flows of this type have numerous applications in the energy, pharmaceuticals, and chemicals process industries. Typical applications include pulverized coal combustion, flow and heat transfer in bubbling and circulating fluidized beds, hopper and chute flows, pneumatic transport of pharmaceutical powders and pellets, and many more. The present work addresses the study of gas-solid flows using computational fluid dynamics (CFD) techniques and discrete element simulation methods (DES) combined. Many previous studies of coupled gas-solid flows have been performed assuming the solid phase as a continuum with averaged properties and treating the gas-solid flow as constituting of interpenetrating continua. Instead, in the present work, the gas phase flow is simulated using continuum theory and the solid phase flow is simulated using DES. DES treats each solid particle individually, thus accounting for its dynamics due to particle-particle interactions, particle-wall interactions as well as fluid drag and buoyancy. The present work involves developing efficient DES methods for dense granular flow and coupling this simulation to continuum simulations of the gas phase flow. Simulations have been performed to observe pure granular behavior in vibrating beds. Benchmark cases have been simulated and the results obtained match the published literature. The dimensionless acceleration amplitude and the bed height are the parameters governing bed behavior. Various interesting behaviors such as heaping, round and cusp surface standing waves, as well as kinks, have been observed for different values of the acceleration amplitude for a given bed height. Furthermore, binary granular mixtures (granular mixtures with two particle sizes) in a vibrated bed have also been studied. Gas-solid flow simulations have been performed to study fluidized beds. Benchmark 2D

  3. An iterative method for hydrodynamic interactions in Brownian dynamics simulations of polymer dynamics

    Science.gov (United States)

    Miao, Linling; Young, Charles D.; Sing, Charles E.

    2017-07-01

    Brownian Dynamics (BD) simulations are a standard tool for understanding the dynamics of polymers in and out of equilibrium. Quantitative comparison can be made to rheological measurements of dilute polymer solutions, as well as direct visual observations of fluorescently labeled DNA. The primary computational challenge with BD is the expensive calculation of hydrodynamic interactions (HI), which are necessary to capture physically realistic dynamics. The full HI calculation, performed via a Cholesky decomposition every time step, scales with the length of the polymer as O(N3). This limits the calculation to a few hundred simulated particles. A number of approximations in the literature can lower this scaling to O(N2 - N2.25), and explicit solvent methods scale as O(N); however both incur a significant constant per-time step computational cost. Despite this progress, there remains a need for new or alternative methods of calculating hydrodynamic interactions; large polymer chains or semidilute polymer solutions remain computationally expensive. In this paper, we introduce an alternative method for calculating approximate hydrodynamic interactions. Our method relies on an iterative scheme to establish self-consistency between a hydrodynamic matrix that is averaged over simulation and the hydrodynamic matrix used to run the simulation. Comparison to standard BD simulation and polymer theory results demonstrates that this method quantitatively captures both equilibrium and steady-state dynamics after only a few iterations. The use of an averaged hydrodynamic matrix allows the computationally expensive Brownian noise calculation to be performed infrequently, so that it is no longer the bottleneck of the simulation calculations. We also investigate limitations of this conformational averaging approach in ring polymers.

  4. Simulation methods to estimate design power: an overview for applied research

    Science.gov (United States)

    2011-01-01

    Background Estimating the required sample size and statistical power for a study is an integral part of study design. For standard designs, power equations provide an efficient solution to the problem, but they are unavailable for many complex study designs that arise in practice. For such complex study designs, computer simulation is a useful alternative for estimating study power. Although this approach is well known among statisticians, in our experience many epidemiologists and social scientists are unfamiliar with the technique. This article aims to address this knowledge gap. Methods We review an approach to estimate study power for individual- or cluster-randomized designs using computer simulation. This flexible approach arises naturally from the model used to derive conventional power equations, but extends those methods to accommodate arbitrarily complex designs. The method is universally applicable to a broad range of designs and outcomes, and we present the material in a way that is approachable for quantitative, applied researchers. We illustrate the method using two examples (one simple, one complex) based on sanitation and nutritional interventions to improve child growth. Results We first show how simulation reproduces conventional power estimates for simple randomized designs over a broad range of sample scenarios to familiarize the reader with the approach. We then demonstrate how to extend the simulation approach to more complex designs. Finally, we discuss extensions to the examples in the article, and provide computer code to efficiently run the example simulations in both R and Stata. Conclusions Simulation methods offer a flexible option to estimate statistical power for standard and non-traditional study designs and parameters of interest. The approach we have described is universally applicable for evaluating study designs used in epidemiologic and social science research. PMID:21689447

  5. Direct simulation Monte Carlo method for gas cluster ion beam technology

    CERN Document Server

    Insepov, Z

    2003-01-01

    A direct simulation Monte Carlo method has been developed and applied for the simulation of a supersonic Ar gas expansion through a converging-diverging nozzle, with the stagnation pressures of P sub 0 =0.1-10 atm, at various temperatures. A body-fitted coordinate system has been developed that allows modeling nozzles of arbitrary shape. A wide selection of nozzle sizes, apex angles, with diffuse and specular atomic reflection laws from the nozzle walls, has been studied. The results of nozzle simulation were used to obtain a scaling law P sub 0 T sub 0 sup 1 sup 9 sup / sup 8 d supalpha L sub n supbeta=const. for the constant mean cluster sizes that are formed in conical nozzles. The Hagena's formula, valid for the conical nozzles with a constant length, has further been extended to the conical nozzles with variable lengths, based on our simulation results.

  6. A numerical simulation method and analysis of a complete thermoacoustic-Stirling engine.

    Science.gov (United States)

    Ling, Hong; Luo, Ercang; Dai, Wei

    2006-12-22

    Thermoacoustic prime movers can generate pressure oscillation without any moving parts on self-excited thermoacoustic effect. The details of the numerical simulation methodology for thermoacoustic engines are presented in the paper. First, a four-port network method is used to build the transcendental equation of complex frequency as a criterion to judge if temperature distribution of the whole thermoacoustic system is correct for the case with given heating power. Then, the numerical simulation of a thermoacoustic-Stirling heat engine is carried out. It is proved that the numerical simulation code can run robustly and output what one is interested in. Finally, the calculated results are compared with the experiments of the thermoacoustic-Stirling heat engine (TASHE). It shows that the numerical simulation can agrees with the experimental results with acceptable accuracy.

  7. Review of Methods Related to Assessing Human Performance in Nuclear Power Plant Control Room Simulations

    Energy Technology Data Exchange (ETDEWEB)

    Katya L Le Blanc; Ronald L Boring; David I Gertman

    2001-11-01

    With the increased use of digital systems in Nuclear Power Plant (NPP) control rooms comes a need to thoroughly understand the human performance issues associated with digital systems. A common way to evaluate human performance is to test operators and crews in NPP control room simulators. However, it is often challenging to characterize human performance in meaningful ways when measuring performance in NPP control room simulations. A review of the literature in NPP simulator studies reveals a variety of ways to measure human performance in NPP control room simulations including direct observation, automated computer logging, recordings from physiological equipment, self-report techniques, protocol analysis and structured debriefs, and application of model-based evaluation. These methods and the particular measures used are summarized and evaluated.

  8. Three-dimensional implementation of the Low Diffusion method for continuum flow simulations

    Science.gov (United States)

    Mirza, A.; Nizenkov, P.; Pfeiffer, M.; Fasoulas, S.

    2017-11-01

    Concepts of a particle-based continuum method have existed for many years. The ultimate goal is to couple such a method with the Direct Simulation Monte Carlo (DSMC) in order to bridge the gap of numerical tools in the treatment of the transitional flow regime between near-equilibrium and rarefied gas flows. For this purpose, the Low Diffusion (LD) method, introduced first by Burt and Boyd, offers a promising solution. In this paper, the LD method is revisited and the implementation in a modern particle solver named PICLas is given. The modifications of the LD routines enable three-dimensional continuum flow simulations. The implementation is successfully verified through a series of test cases: simple stationary shock, oblique shock simulation and thermal Couette flow. Additionally, the capability of this method is demonstrated by the simulation of a hypersonic nitrogen flow around a 70°-blunted cone. Overall results are in very good agreement with experimental data. Finally, the scalability of PICLas using LD on a high performance cluster is presented.

  9. Automated local line rolling forming and simplified deformation simulation method for complex curvature plate of ships

    Directory of Open Access Journals (Sweden)

    Y. Zhao

    2017-06-01

    Full Text Available Local line rolling forming is a common forming approach for the complex curvature plate of ships. However, the processing mode based on artificial experience is still applied at present, because it is difficult to integrally determine relational data for the forming shape, processing path, and process parameters used to drive automation equipment. Numerical simulation is currently the major approach for generating such complex relational data. Therefore, a highly precise and effective numerical computation method becomes crucial in the development of the automated local line rolling forming system for producing complex curvature plates used in ships. In this study, a three-dimensional elastoplastic finite element method was first employed to perform numerical computations for local line rolling forming, and the corresponding deformation and strain distribution features were acquired. In addition, according to the characteristics of strain distributions, a simplified deformation simulation method, based on the deformation obtained by applying strain was presented. Compared to the results of the three-dimensional elastoplastic finite element method, this simplified deformation simulation method was verified to provide high computational accuracy, and this could result in a substantial reduction in calculation time. Thus, the application of the simplified deformation simulation method was further explored in the case of multiple rolling loading paths. Moreover, it was also utilized to calculate the local line rolling forming for the typical complex curvature plate of ships. Research findings indicated that the simplified deformation simulation method was an effective tool for rapidly obtaining relationships between the forming shape, processing path, and process parameters.

  10. Patient Specific Simulation for Planning of Cochlear Implantation Surgery

    DEFF Research Database (Denmark)

    Vera, Sergio; Perez, Frederic; Balust, Clara

    2014-01-01

    Cochlear implantation is a surgical procedure that can restore the hearing capabilities to patients with severe or complete functional loss. However, the level of restoration varies highly between subjects and depends on patient-specific factors. This paper presents a software application for pla...

  11. Efficient method for time-domain simulation of the linear feedback systems containing fractional order controllers.

    Science.gov (United States)

    Merrikh-Bayat, Farshad

    2011-04-01

    One main approach for time-domain simulation of the linear output-feedback systems containing fractional-order controllers is to approximate the transfer function of the controller with an integer-order transfer function and then perform the simulation. In general, this approach suffers from two main disadvantages: first, the internal stability of the resulting feedback system is not guaranteed, and second, the amount of error caused by this approximation is not exactly known. The aim of this paper is to propose an efficient method for time-domain simulation of such systems without facing the above mentioned drawbacks. For this purpose, the fractional-order controller is approximated with an integer-order transfer function (possibly in combination with the delay term) such that the internal stability of the closed-loop system is guaranteed, and then the simulation is performed. It is also shown that the resulting approximate controller can effectively be realized by using the proposed method. Some formulas for estimating and correcting the simulation error, when the feedback system under consideration is subjected to the unit step command or the unit step disturbance, are also presented. Finally, three numerical examples are studied and the results are compared with the Oustaloup continuous approximation method. Copyright © 2011 ISA. Published by Elsevier Ltd. All rights reserved.

  12. Application of CLEAR-VOF method to wave and flow simulations

    Directory of Open Access Journals (Sweden)

    Ying-wei SUN

    2012-03-01

    Full Text Available A two-dimensional numerical model based on the Navier-Stokes equations and computational Lagrangian-Eulerian advection remap-volume of fluid (CLEAR-VOF method was developed to simulate wave and flow problems. The Navier-Stokes equations were discretized with a three-step finite element method that has a third-order accuracy. In the CLEAR-VOF method, the VOF function F was calculated in the Lagrangian manner and allowed the complicated free surface to be accurately captured. The propagation of regular waves and solitary waves over a flat bottom, and shoaling and breaking of solitary waves on two different slopes were simulated with this model, and the numerical results agreed with experimental data and theoretical solutions. A benchmark test of dam-collapse flow was also simulated with an unstructured mesh, and the capability of the present model for wave and flow simulations with unstructured meshes, was verified. The results show that the model is effective for numerical simulation of wave and flow problems with both structured and unstructured meshes.

  13. A general method for closed-loop inverse simulation of helicopter maneuver flight

    Directory of Open Access Journals (Sweden)

    Wei WU

    2017-12-01

    Full Text Available Maneuverability is a key factor to determine whether a helicopter could finish certain flight missions successfully or not. Inverse simulation is commonly used to calculate the pilot controls of a helicopter to complete a certain kind of maneuver flight and to assess its maneuverability. A general method for inverse simulation of maneuver flight for helicopters with the flight control system online is developed in this paper. A general mathematical describing function is established to provide mathematical descriptions of different kinds of maneuvers. A comprehensive control solver based on the optimal linear quadratic regulator theory is developed to calculate the pilot controls of different maneuvers. The coupling problem between pilot controls and flight control system outputs is well solved by taking the flight control system model into the control solver. Inverse simulation of three different kinds of maneuvers with different agility requirements defined in the ADS-33E-PRF is implemented based on the developed method for a UH-60 helicopter. The results show that the method developed in this paper can solve the closed-loop inverse simulation problem of helicopter maneuver flight with high reliability as well as efficiency. Keywords: Closed-loop, Flying quality, Helicopters, Inverse simulation, Maneuver flight

  14. Methods to improve patient recruitment and retention in stroke trials

    DEFF Research Database (Denmark)

    Berge, Eivind; Stapf, Christian; Al-Shahi Salman, Rustam

    2016-01-01

    Background: The success of randomized-controlled stroke trials is dependent on the recruitment and retention of a sufficient number of patients, but fewer than half of all trials meet their target number of patients. Methods: We performed a search and review of the literature, and conducted...... a survey and workshop among 56 European stroke trialists, to identify barriers, suggest methods to improve recruitment and retention, and make a priority list of interventions that merit further evaluation. Results: The survey and workshop identified a number of barriers to patient recruitment...... and retention, from patients’ incapacity to consent, to handicaps that prevent patients from participation in trial-specific follow-up. Methods to improve recruitment and retention may include simple interventions with individual participants, funding of research networks, and reimbursement of new treatments...

  15. REHABILITATION OF PATIENTS WITH APHASIA USING MODIFIED RESTORATION METHODS

    Directory of Open Access Journals (Sweden)

    M. M. Shcherbakova

    2014-01-01

    Full Text Available Backgroud: There is a high prevalence of vascular diseases of the brain in adult population. One of the most severe complications of the cerebral vascular diseases is an aphasia leading to patient’s disability. An extremely severe and unreversible condition for further rehabilitation is noted in a group of patients which develops an impressive speech impairment as a dominant disturbance associated with aphasia. Aim: To identify the most effective rehabilitation method for patients with complications of cerebral circulation disturbances manifesting as speech impairment in a form of aphasia. Materials and methods: Theoretical aspect of rehabilitation in post-stroke aphasia patients with a dominant impressive speech impairment was studied. All patients underwent neurologic examination, dynamic logopedic observation, and magnetic resonance imaging. The patients of the chosen group underwent rehabilitation with a modified modality of speech restoration. Results: Introduction of the modified rehabilitation methods into the logopedics practice proved their high efficiency. Significant improvement was seen in 64% of patients with acoustic-amnestic aphasia, in 57% of patients with acoustic-gnostic aphasia, and in 60% of those with semantic aphasia. Conclusion: A key moment for achievement of the high rehabilitation outcome is a complex approach needed for rehabilitation of patients with the consequences of the acute impairments of cerebral circulation.

  16. Use of clinical simulations for patient education: targeting an untapped audience.

    Science.gov (United States)

    Siwe, Karin; Berterö, Carina; Pugh, Carla; Wijma, Barbro

    2009-01-01

    In most cases, the health professional has been the target for simulation based learning curricula. We have developed a simulation based curriculum for patient education. In our curriculum lay-women learn how to perform the clinical female pelvic examination using a manikin-based trainer. Learner assessments show that prior negative expectations turned into positive expectations regarding future pelvic examinations.

  17. Test of a Cardiology Patient Simulator with Students in Fourth-Year Electives.

    Science.gov (United States)

    Ewy, Gordon A.; And Others

    1987-01-01

    Students at five medical schools participated in an evaluation of a cardiology patient simulator (CPS), a life-size mannequin capable of simulating a wide variety of cardiovascular conditions. The CPS enhances learning both the knowledge and the skills necessary to perform a bedside cardiovascular evaluation. (Author/MLW)

  18. Using Patient-Simulators to Teach Telephone Communication Skills to Health Professionals.

    Science.gov (United States)

    Evens, Susan; Curtis, Peter

    1983-01-01

    A cost-effective audiotaped patient-simulation program to teach residents at a university family practice center is described. Similar programs have been implemented in other areas such as pediatrics, psychiatry, nursing, and a family medicine clerkship. (MSE)

  19. Medical students' medication communication skills regarding drug prescription-a qualitative analysis of simulated physician-patient consultations.

    Science.gov (United States)

    Hauser, Katarina; Matthes, Jan

    2017-04-01

    Poor medication communication of physicians to patients is detrimental, e.g. for medication adherence. Reasons for physicians' deficits in medication communication may be unfavourable conditions in daily practice or already insufficient training during their (undergraduate) medical studies. We explored medical students' communication on new medications in simulated physician-patient conversations to identify actual deficits indicating apparent educational needs. Fifth year medical students attending a mandatory course at the University of Cologne had simulated physician-patient consultations aiming at drug prescription. In 2015, 21 consultations were recorded, transcribed and subjected to qualitative content analysis based on the method of inductive coding. Even essential information on drug therapy was often lacking (e.g. adverse effects, drug administration). Some aspects were addressed more frequently than others. This seemed to differ depending on the diagnosis underlying the particular treatment (acute event vs. chronic disease). The extent of information on drug treatments given in simulated physician-patient consultations varied significantly between students. Fifth year medical students showed appreciable deficits in communicating drug prescriptions to patients though there were remarkable inter-individual differences. Our findings suggest that communication on drug therapy to patients is no self-evolving skill. Thus, there is obviously a need for emphasizing medication communication in the training of medical students. Communication aids specifically aiming at medication communication might facilitate learning of adequate medication communication skills.

  20. A Multi-Stage Method for Connecting Participatory Sensing and Noise Simulations

    Directory of Open Access Journals (Sweden)

    Mingyuan Hu

    2015-01-01

    Full Text Available Most simulation-based noise maps are important for official noise assessment but lack local noise characteristics. The main reasons for this lack of information are that official noise simulations only provide information about expected noise levels, which is limited by the use of large-scale monitoring of noise sources, and are updated infrequently. With the emergence of smart cities and ubiquitous sensing, the possible improvements enabled by sensing technologies provide the possibility to resolve this problem. This study proposed an integrated methodology to propel participatory sensing from its current random and distributed sampling origins to professional noise simulation. The aims of this study were to effectively organize the participatory noise data, to dynamically refine the granularity of the noise features on road segments (e.g., different portions of a road segment, and then to provide a reasonable spatio-temporal data foundation to support noise simulations, which can be of help to researchers in understanding how participatory sensing can play a role in smart cities. This study first discusses the potential limitations of the current participatory sensing and simulation-based official noise maps. Next, we explain how participatory noise data can contribute to a simulation-based noise map by providing (1 spatial matching of the participatory noise data to the virtual partitions at a more microscopic level of road networks; (2 multi-temporal scale noise estimations at the spatial level of virtual partitions; and (3 dynamic aggregation of virtual partitions by comparing the noise values at the relevant temporal scale to form a dynamic segmentation of each road segment to support multiple spatio-temporal noise simulations. In this case study, we demonstrate how this method could play a significant role in a simulation-based noise map. Together, these results demonstrate the potential benefits of participatory noise data as dynamic