WorldWideScience

Sample records for shortkeep feeder costs

  1. Optimal distribution feeder reconfiguration for increasing the penetration of plug-in electric vehicles and minimizing network costs

    International Nuclear Information System (INIS)

    Kavousi-Fard, Abdollah; Abbasi, Alireza; Rostami, Mohammad-Amin; Khosravi, Abbas

    2015-01-01

    Appearance of PEVs (Plug-in Electric Vehicles) in future transportation sector brings forward opportunities and challenges from grid perspective. Increased utilization of PEVs will result in problems such as greater total loss, unbalanced load factor, feeder congestion and voltage drop. PEVs are mobile energy storages dispersed all over the network with benefits to both owners and utilities in case of V2G (Vehicle-to-Grid) possibility. The intelligent bidirectional power flow between grid and large number of vehicles adds complexity to the system and requires operative tools to schedule V2G energy and subdue PEV impacts. In this paper, DFR (Distribution Feeder Reconfiguration) is utilized to optimally coordinate PEV operation in a stochastic framework. Uncertainty in PEVs characteristics can be due to several sources from location and time of grid connection to driving pattern and battery SoC (State-of-Charge). The proposed stochastic problem is solved with a self-adaptive evolutionary swarm algorithm based on SSO (Social Spider Optimization) algorithm. Numerical studies verify the efficacy of the proposed DFR to improve the system performance and optimal dispatch of V2G. - Highlights: • Consideration effect of PEVS on the distribution feeder reconfiguration. • Increasing the penetration of PEVS. • Introducing a new artificial optimization algorithm. • Modeling the uncertainty in network. • Investigating the degradation cost of batteries in V2G technology.

  2. The Cost of Distribution System Upgrades to Accommodate Increasing Penetrations of Distributed Photovoltaic Systems on Real Feeders in the United States

    Energy Technology Data Exchange (ETDEWEB)

    Horowitz, Kelsey A [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Ding, Fei [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Mather, Barry A [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Palmintier, Bryan S [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2018-04-05

    The increasing deployment of distributed photovoltaic systems (DPV) can impact operations at the distribution level and the transmission level of the electric grid. It is important to develop and implement forward-looking approaches for calculating distribution upgrade costs that can be used to inform system planning, market and tariff design, cost allocation, and other policymaking as penetration levels of DPV increase. Using a bottom-up approach that involves iterative hosting capacity analysis, this report calculates distribution upgrade costs as a function of DPV penetration on three real feeders - two in California and one in the Northeastern United States.

  3. CATTLE FEEDER BEHAVIOR AND FEEDER CATTLE PLACEMENTS

    OpenAIRE

    Kastens, Terry L.; Schroeder, Ted C.

    1994-01-01

    Cattle feeders appear irrational when they place cattle on feed when projected profit is negative. Long futures positions appear to offer superior returns to cattle feeding investment. Cattle feeder behavior suggests that they believe a downward bias in live cattle futures persists and that cattle feeders use different expectations than the live cattle futures market price when making placement decisions. This study examines feeder cattle placement determinants, comparing performance of expec...

  4. Design of apron feeders

    Energy Technology Data Exchange (ETDEWEB)

    Ramos, C.M.

    1987-12-01

    This paper discusses practical aspects of apron feeder design, and includes information on how to make the first selection. Various aspects of design such as feeder speed, material depth, chain-pitch, roller loading, wheels/sprockets and chain roller friction are elaborated in detail. 8 refs., 14 figs., 12 tabs.

  5. Impact of flow accelerated corrosion (FAC) on feeder refurbishment planning

    International Nuclear Information System (INIS)

    Jyrkama, M.; Pandey, M.

    2010-01-01

    Feeder wall thinning due to flow accelerated corrosion (FAC) may result in a large number of feeder replacements in the future. In this study, the process of FAC is modelled using a probabilistic approach and used to predict the expected number of degraded feeders and their replacements in the future. Because of the high cost associated with feeder replacements, it may be optimal to replace the entire feeder population during a single refurbishment outage when the unit cost of replacement is likely to be less. The results of this study demonstrate, however, that the unit cost of feeder replacement must be sufficiently lower than the standard replacement cost and the refurbishment performed at an optimal time to realize the economic benefits associated with the refurbishment. (author)

  6. Feederism in a woman.

    Science.gov (United States)

    Terry, Lesley L; Vasey, Paul L

    2011-06-01

    Feederism is a fat fetish subculture in which individuals eroticize weight gain and feeding. Feeders are individuals who claim to become sexually aroused by feeding their partners and encouraging them to gain weight. Conversely, Feedees are individuals who claim to become sexually aroused by eating, being fed, and the idea or act of gaining weight. Very little is known about this population. This report describes a woman who self-identified as a Feedee. It is unclear, at present, whether female Feederism represents a unique paraphilia or a thematic variation of morphophilia or sexual masochism.

  7. Comprehensive Cost Minimization in Distribution Networks Using Segmented-time Feeder Reconfiguration and Reactive Power Control of Distributed Generators

    DEFF Research Database (Denmark)

    Chen, Shuheng; Hu, Weihao; Chen, Zhe

    2016-01-01

    In this paper, an efficient methodology is proposed to deal with segmented-time reconfiguration problem of distribution networks coupled with segmented-time reactive power control of distributed generators. The target is to find the optimal dispatching schedule of all controllable switches...... and distributed generators’ reactive powers in order to minimize comprehensive cost. Corresponding constraints, including voltage profile, maximum allowable daily switching operation numbers (MADSON), reactive power limits, and so on, are considered. The strategy of grouping branches is used to simplify...... (FAHPSO) is implemented in VC++ 6.0 program language. A modified version of the typical 70-node distribution network and several real distribution networks are used to test the performance of the proposed method. Numerical results show that the proposed methodology is an efficient method for comprehensive...

  8. Economic feeder for recharging and ``topping off''

    Science.gov (United States)

    Fickett, Bryan; Mihalik, G.

    2000-04-01

    Increasing the size of the melt charge significantly increases yield and reduces costs. Siemens Solar Industries is optimizing a method to charge additional material after meltdown (top-off) using an external feeder system. A prototype feeder system was fabricated consisting of a hopper and feed delivery system. The low-cost feeder is designed for simple operation and maintenance. The system is capable of introducing up to 60 kg of granular silicon while under vacuum. An isolation valve permits refilling of the hopper while maintaining vacuum in the growth furnace. Using the feeder system in conjunction with Siemens Solar Industries' energy efficient hot zone dramatically reduces power and argon consumption. Throughput is also improved as faster pull speeds can be attained. The increased pull speeds have an even greater impact when the charge size is increased. Further cost reduction can be achieved by refilling the crucible after crystal growth and pulling a second ingot run. Siemens Solar Industries is presently testing the feeder in production.

  9. Dry piston coal feeder

    Science.gov (United States)

    Hathaway, Thomas J.; Bell, Jr., Harold S.

    1979-01-01

    This invention provides a solids feeder for feeding dry coal to a pressurized gasifier at elevated temperatures substantially without losing gas from the gasifier by providing a lock having a double-acting piston that feeds the coals into the gasifier, traps the gas from escaping, and expels the trapped gas back into the gasifier.

  10. Feeder replacement tooling and processes

    International Nuclear Information System (INIS)

    Mallozzi, R.; Goslin, R.; Pink, D.; Askari, A.

    2008-01-01

    Primary heat transport system feeder integrity has become a concern at some CANDU nuclear plants as a result of thinning caused by flow accelerated corrosion (FAC). Feeder inspections are indicating that life-limiting wall thinning can occur in the region between the Grayloc hub weld and second elbow of some outlet feeders. In some cases it has become necessary to replace thinned sections of affected feeders to restore feeder integrity to planned end of life. Atomic Energy of Canada Limited (AECL) and Babcock and Wilcox Canada Ltd. (B and W) have developed a new capability for replacement of single feeders at any location on the reactor face without impacting or interrupting operation of neighbouring feeders. This new capability consists of deploying trained crews with specialized tools and procedures for feeder replacements during planned outages. As may be expected, performing single feeder replacement in the congested working environment of an operational CANDU reactor face involves overcoming many challenges with respect to access to feeders, available clearances for tooling, and tooling operation and performance. This paper describes some of the challenges encountered during single feeder replacements and actions being taken by AECL and B and W to promote continuous improvement of feeder replacement tooling and processes and ensure well-executed outages. (author)

  11. Development of dry coal feeders

    Science.gov (United States)

    Bonin, J. H.; Cantey, D. E.; Daniel, A. D., Jr.; Meyer, J. W.

    1977-01-01

    Design and fabrication of equipment of feed coal into pressurized environments were investigated. Concepts were selected based on feeder system performance and economic projections. These systems include: two approaches using rotating components, a gas or steam driven ejector, and a modified standpipe feeder concept. Results of development testing of critical components, design procedures, and performance prediction techniques are reviewed.

  12. Round-bale feeder design affects hay waste and economics during horse feeding.

    Science.gov (United States)

    Martinson, K; Wilson, J; Cleary, K; Lazarus, W; Thomas, W; Hathaway, M

    2012-03-01

    Many horse owners find round bales convenient, less labor intensive, and more affordable than other hay types, but report an inability to control horse BW gain and excessive hay waste. The objectives were to compare hay waste, hay intake, and payback of 9 round-bale feeders and a no-feeder control when used during horse feeding. Nine round-bale feeders were tested: Cinch Net, Cone, Covered Cradle, Hayhut, Hay Sleigh, Ring, Tombstone, Tombstone Saver, and Waste Less. Each feeder design was placed on the ground in a dirt paddock. Five groups of 5 horses were fed in rotation for a 4-d period with each feeder. Every fourth day, groups were rotated among paddocks and a new round bale was placed in each feeder. In the 5 paddocks used, 5 feeders were installed for d 1 through 20, and the remaining 4 feeders and no-feeder control were installed for d 21 through 40. Groups of horses were sequentially assigned to feeders using two 5 × 5 Latin squares, the first for d 1 through 20, the second for d 21 through 40. Horse groups of similar age, BW, breed, and sex were formed from 25 Quarter Horse and Thoroughbred geldings and open mares (means: 11 yr; 541 kg of BW). Hay on the ground surrounding the feeder was collected daily, dried, and weighed. The total amount of hay removed around each feeder for a 4-d period was considered waste. Dry matter intake was estimated as the difference between hay disappearance and waste. Number of months for the reduction in waste to repay feeder cost (payback) were calculated using hay valued at $110/t, and improved feeder efficiency over the control. Feeder design did not affect hay intake (P > 0.05); all feeders resulted in an estimated hay intake of 2.0 to 2.4% BW; the no-feeder control resulted in a reduced intake of 1.3% BW (P = 0.001). Mean percentage of hay waste differed among feeders (P feeder control, 57%. Feeder design also affected payback (P feeder design affected hay waste and payback, but not estimated hay intake or BW change

  13. A HYBRID APPROACH FOR RURAL FEEDER DESIGN

    Directory of Open Access Journals (Sweden)

    DAMANJEET KAUR

    2012-08-01

    Full Text Available In this paper, a population based approach for conductor size selection in rural radial distribution system is presented. The proposed hybrid approach implies a particle swarm optimization (PSO approach in combination with mutant property of differential evolution (DE for conductor size selection in radial distribution system. The conductor size for each feeder segment is selected such that the total cost of capital investment and capitalized cost of energy losses is minimized while constraints of voltage at each node and current carrying capacity of conductor is within the limits. The applicability and effectiveness of the proposed method is demonstrated with the help of 32-node test system.

  14. An evaluation of the choice of feeder cell growth arrest for the production of cultured epidermis.

    Science.gov (United States)

    Chugh, Rishi Man; Chaturvedi, Madhusudan; Yerneni, Lakshmana Kumar

    2015-12-01

    Growth arrested 3T3 cells have been used as feeder cells in human epidermal keratinocyte cultures to produce cultured epidermal autografts for the treatment of burns. The feeder cells were ideally growth-arrested by gamma-irradiation. Alternatively, growth arrest by mitomycin C treatment is a cost effective option. We compared the functional efficacy of these two approaches in keratinocyte cultures by colony forming efficiency, the net growth area of colonies, BrdU labeling and histological features of cultured epidermal sheets. The growth area estimation involved a semi-automated digital technique using the Adobe Photoshop and comprised of isolation and enumeration of red pixels in Rhodamine B-stained keratinocyte colonies. A further refinement of the technique led to the identification of critical steps to increasing the degree of accuracy and enabling its application as an extension of colony formation assay. The results on feeder cell functionality revealed that the gamma irradiated feeders influenced significantly higher colony forming efficiency and larger growth area than the mitomycin C treated feeders. The BrdU labeling study indicated significant stimulation of the overall keratinocyte proliferation by the gamma irradiated feeders. The cultured epidermal sheets produced by gamma feeders were relatively thicker than those produced by mitomycin C feeders. We discussed the clinical utility of mitomycin C feeders from the viewpoint of cost-effective burn care in developing countries. Copyright © 2015 Elsevier Ltd and ISBI. All rights reserved.

  15. Evaluation of options for life cycle management of feeder cracking at the Point Lepreau Generating Station

    International Nuclear Information System (INIS)

    Gendron, T.S.; Slade, J.P.

    2003-01-01

    The CANDU industry has a predictive capability for most Heat Transport System (HTS) degradation issues that allows utilities to apply cost-effective maintenance programs. The standard approach for maintenance programs is focussed inspection and planned replacement. Some examples of degradation issues with deterministic failure rates are feeder thinning, and pressure tube elongation and deuterium ingress. However, the cracking observed in Point Lepreau Generating Station (PLGS) outlet feeder first bends is one notable exception to this behaviour. A predictive capability for feeder cracking does not currently exist for several reasons. First, the mechanism of feeder cracking, stress corrosion cracking (SCC), has to some degree a random nature. Second, although a probable environment causing cracking has been identified, the precise stress and environmental conditions for feeder crack initiation and propagation have not been defined. Finally, the very low incidence of feeder cracking observed to-date (four, all at PLGS) precludes a probabilistic or statistical prediction of failure rate. Generally, utilities select a Life Cycle Management Plan that ensures safe operation and has the lowest Net Present Value cost. In preparing a Feeder Life Cycle Management Plan, New Brunswick Power (NBP) has recognized that the Net Present Value cost is very sensitive to failure rate. Since the failure rate for feeder cracking is not well defined, the following three scenarios were considered to bound the probability of future failures at PLGS. (author)

  16. Leaky feeder: the communication backbone

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-01-01

    The need to communicate with all areas of the underground operation in monitoring the movement of men, materials and vehicles, as well as the optimum performance of conveyor systems, has been effectively met with the installation of a Flexcom leaky feeder cable network at a coliery in Mpumalanga. Installed by the South African subsidiary of Mine Radio Systems (MRS), based in Canada, Flexcom is an RF communications highway for underground mines. The system can provide up to 32 voice/data control channels and up to 16 video channels, all operating simultaneously. The system uses a series of bi-directional amplifiers (or signal boosters) spaced at 350 m intervals along the leaky feeder cable, with branching units and termination units added as required. Communication is possible within 50 m of the leaky feeder cable. MRS has 11 conveyors monitored via the SCADA program at the mine and the system produces reports as required which are accessible via cellphone from anywhere in the world. The wireless monitoring of miners and equipment contributes to mine safety. 3 figs.

  17. A Feeder-Bus Dispatch Planning Model for Emergency Evacuation in Urban Rail Transit Corridors

    Science.gov (United States)

    Wang, Yun; Yan, Xuedong; Zhou, Yu; Zhang, Wenyi

    2016-01-01

    The mobility of modern metropolises strongly relies on urban rail transit (URT) systems, and such a heavy dependence causes that even minor service interruptions would make the URT systems unsustainable. This study aims at optimally dispatching the ground feeder-bus to coordinate with the urban rails’ operation for eliminating the effect of unexpected service interruptions in URT corridors. A feeder-bus dispatch planning model was proposed for the collaborative optimization of URT and feeder-bus cooperation under emergency situations and minimizing the total evacuation cost of the feeder-buses. To solve the model, a concept of dummy feeder-bus system is proposed to transform the non-linear model into traditional linear programming (ILP) model, i.e., traditional transportation problem. The case study of Line #2 of Nanjing URT in China was adopted to illustrate the model application and sensitivity analyses of the key variables. The modeling results show that as the evacuation time window increases, the total evacuation cost as well as the number of dispatched feeder-buses decrease, and the dispatched feeder-buses need operate for more times along the feeder-bus line. The number of dispatched feeder-buses does not show an obvious change with the increase of parking spot capacity and time window, indicating that simply increasing the parking spot capacity would cause huge waste for the emergent bus utilization. When the unbalanced evacuation demand exists between stations, the more feeder-buses are needed. The method of this study will contribute to improving transportation emergency management and resource allocation for URT systems. PMID:27676179

  18. in meat production III. Feeder - breeder dimorphism

    African Journals Online (AJOL)

    Feeder- breeder dimorphism is advantageous when large offspring for slaughter is obtained from small breeding animals. The effect of feeder- breeder dimorphism on herd efficiency is evaluated for terminal crossbreeding and growth modification by biotechnological or dietary means. Selection criteria for breeds or lines in ...

  19. Demonstration of Market-Based Real-Time Electricity Pricing on a Congested Feeder

    DEFF Research Database (Denmark)

    Larsen, Emil Mahler; Pinson, Pierre; le Ray, Guillaume

    2015-01-01

    Congestion management can delay grid reinforcements needed due to the growth of distributed technologies like photovoltaics and electric vehicles. This paper presents a method of congestion management for low voltage feeders using indirect control from the smart grid demonstration EcoGrid EU, where...... prices to 1900 houses, with a virtual feeder of 28 houses receiving congestion pricing. Simulations are used to calculate the cost from using this congestion management method, while demonstration results indicate that congestion can be managed successfully....

  20. An RFID Based Smart Feeder for Hummingbirds.

    Science.gov (United States)

    Ibarra, Vicente; Araya-Salas, Marcelo; Tang, Yu-ping; Park, Charlie; Hyde, Anthony; Wright, Timothy F; Tang, Wei

    2015-12-16

    We present an interdisciplinary effort to record feeding behaviors and control the diet of a hummingbird species (Phaethornis longirostris, the long-billed hermit or LBH) by developing a Radio Frequency Identification (RFID) based smart feeder. The system contains an RFID reader, a microcontroller, and a servo-controlled hummingbird feeder opener; the system is presented as a tool for studying the cognitive ability of the LBH species. When equipped with glass capsule RFID tags (which are mounted on the hummingbird), the smart feeder can provide specific diets for predetermined sets of hummingbirds at the discretion of biologists. This is done by reading the unique RFID tag on the hummingbirds and comparing the ID number with the pre-programmed ID numbers stored in the smart feeder. The smart feeder records the time and ID of each hummingbird visit. The system data is stored in a readily available SD card and is powered by two 9 V batteries. The detection range of the system is approximately 9-11 cm. Using this system, biologists can assign the wild hummingbirds to different experimental groups and monitor their diets to determine if they develop a preference to any of the available nectars. During field testing, the smart feeder system has demonstrated consistent detection (when compared to detections observed by video-recordings) of RFID tags on hummingbirds and provides pre-designed nectars varying water and sugar concentrations to target individuals. The smart feeder can be applied to other biological and environmental studies in the future.

  1. A study of inter linkage effects on Candu feeder piping

    International Nuclear Information System (INIS)

    Li, M.; Aggarwal, M.L.; Meysner, A.

    2005-01-01

    A CANDU (Canadian Deuterium Uranium) reactor core consists of a large number of fuel channels where heat is generated. Two feeder pipes are connected to each fuel channel to transport D 2 O coolant into and out of the reactor core. The feeder piping is designed to the requirements of Class 1 piping of Section III NB of the ASME Boiler and Pressure Vessel and CSA Codes. Feeder piping stress analysis is being performed to demonstrate the code compliance check and the fitness for service of feeders. In the past, stress analyses were conducted for each individual feeder without including interaction effects among connected feeders. Interaction effects occur as a result of linkages that exist between feeders to prevent fretting and impacting damage during normal, abnormal and accident conditions. In this paper, a 'combined' approach is adopted to include all feeders connected by inter linkages into one feeder piping model. MSC/NASTRAN finite element software was used in the stress simulation, which contains up to 127 feeder pipes. The ASME Class 1 piping analysis was conducted to investigate the effects of the linkages between feeders. Both seismic time history and broadened response spectra methods were used in the seismic stress calculation. The results show that the effect of linkages is significant in dynamic stresses for all feeder configurations, as well as in static stresses for certain feeder configurations. The single feeder analysis could either underestimate or overestimate feeder stresses depending on the pipe geometry and bend wall thickness. (authors)

  2. An RFID Based Smart Feeder for Hummingbirds

    Directory of Open Access Journals (Sweden)

    Vicente Ibarra

    2015-12-01

    Full Text Available We present an interdisciplinary effort to record feeding behaviors and control the diet of a hummingbird species (Phaethornis longirostris, the long-billed hermit or LBH by developing a Radio Frequency Identification (RFID based smart feeder. The system contains an RFID reader, a microcontroller, and a servo-controlled hummingbird feeder opener; the system is presented as a tool for studying the cognitive ability of the LBH species. When equipped with glass capsule RFID tags (which are mounted on the hummingbird, the smart feeder can provide specific diets for predetermined sets of hummingbirds at the discretion of biologists. This is done by reading the unique RFID tag on the hummingbirds and comparing the ID number with the pre-programmed ID numbers stored in the smart feeder. The smart feeder records the time and ID of each hummingbird visit. The system data is stored in a readily available SD card and is powered by two 9 V batteries. The detection range of the system is approximately 9–11 cm. Using this system, biologists can assign the wild hummingbirds to different experimental groups and monitor their diets to determine if they develop a preference to any of the available nectars. During field testing, the smart feeder system has demonstrated consistent detection (when compared to detections observed by video-recordings of RFID tags on hummingbirds and provides pre-designed nectars varying water and sugar concentrations to target individuals. The smart feeder can be applied to other biological and environmental studies in the future.

  3. Advances in technologies for feeder pipe inspections

    Energy Technology Data Exchange (ETDEWEB)

    Ten Grotenhuis, R.; Verma, Y.; Hitchcox, T.; Sakuta, A. [Ontario Power Generation, Inspection and Maintenance Div., Toronto, Ontario (Canada)

    2014-07-15

    The successful development of the Matrix Inspection Technique (MIT) for feeder weld area applications has been followed up with a project to leverage the technology to address other aspects of feeder inspection. The goal of the project is to adapt the technology to provide full circumferential inspection of feeder pipes for FAC thinning and, potentially, for axial cracking. The project necessitated evolving a new generation of high speed, high element count data acquisition instruments. It also required the development of custom inspection arrays, innovative approaches to sealing the water column, use of inertial motion sensors to synthesize encoder inputs, real-time visual feedback for the operator, and enhanced automated analysis software capable of plotting the inspected configuration in 3D. The individual components of the system are currently being integrated into a whole. The results obtained to date demonstrate the approach to be fundamentally sound. (author)

  4. Vertical-Screw-Auger Conveyer Feeder

    Science.gov (United States)

    Walton, Otis (Inventor); Vollmer, Hubert J. (Inventor)

    2016-01-01

    A conical feeder is attached to a vertically conveying screw auger. The feeder is equipped with scoops and rotated from the surface to force-feed regolith the auger. Additional scoops are possible by adding a cylindrical section above the conical funnel section. Such then allows the unit to collect material from swaths larger in diameter than the enclosing casing pipe of the screw auger. A third element includes a flexible screw auger. All three can be used in combination in microgravity and zero atmosphere environments to drill and recover a wide area of subsurface regolith and entrained volatiles through a single access point on the surface.

  5. Optimal Design of the Feeder-Bus Network Based on the Transfer System

    Directory of Open Access Journals (Sweden)

    Lianbo Deng

    2013-01-01

    Full Text Available This paper studied the classic feeder-bus network design problem (FBNDP, which can be described as follows: for the passenger travel demand between rail stations and bus stops on a given urban transit network, it designs the optimal feeder bus routes and frequencies so as to minimize the passengers’ travel expense and the operator’s cost. We extended the demand pattern of M-to-1 in most existing researches to M-to-M. We comprehensively considered the passenger travel cost, which includes the waiting and riding cost on the bus, riding cost on rail, and transfer cost between these two transportation modes, and presented a new genetic algorithm that determines the optimal feeder-bus operating frequencies under strict constraint conditions. The numerical examples under different demand patterns have been experienced and analysed, which showed the robustness and efficiency of the presented algorithm. We also found that the distribution pattern of the travel demand has a significant influence on the feeder-bus network construction.

  6. Counseling in the Elementary Feeder Schools.

    Science.gov (United States)

    Dunham, Virginia

    This brief paper presents the concept of transition counseling between a junior high school and its feeder school(s), designed to make the change from elementary into junior high less traumatic. Aside from routine sixth grade counseling, the counselors expanded their base of counseling to include all types of problems as well as all grade levels.…

  7. The development and manufacture of size for size feeder pipe for feeder replacement

    International Nuclear Information System (INIS)

    Legate, G.; Schreiter, D.; Townley, N.

    2008-01-01

    The recently recognised problem of feeder pipe thinning created a unique sourcing problem. Operators require relatively small quantities of nuclear class 1 seamless feeder pipe for such replacement which prior to the introduction of this product in 2006 was not available. It was desired that the pipe be produced at the exact size of the pipe currently in use at the specific reactor site (feeder pipe size varies from site to site). Secondly the pipe had to be made in conformance to the original code year of issue and to conform to the intent of the original material specifications. Finally a supply strategy had to be implemented allowing for timely manufacture of replacement piping. This presentation will report upon how replacement size for size feeder tube was developed and is currently manufactured at Nu-Tech Precision Metals. The paper will also detail the current supply strategy to ensure timely manufacture of the product.

  8. Expectations of Cattle Feeding Investors in Feeder Cattle Placements

    OpenAIRE

    Kastens, Terry L.; Schroeder, Ted C.

    1993-01-01

    Cattle feeders appear irrational when they place cattle on feed when projected profits are negative. Long futures positions appear to offer superior returns to cattle feeding investment. Cattle feeder behavior suggests that they believe a downward bias in live cattle futures persists and that cattle feeders use different information than the live cattle futures market price when making placement decisions. This paper examines feeder cattle placement determinants and compares performance of ex...

  9. Computational fluid dynamics analysis for flow accelerated corrosion in CANDU6 feeder pipes

    International Nuclear Information System (INIS)

    Catana, A.; Pauna, E.; Ioan, M.

    2013-01-01

    CANDU6 plant management over a long time period includes various ageing and degradation mechanisms like FAC manifested mainly at first and second elbow of CANDU6 outlet feeders. FAC take place at all CANDU6 built before 2000 year with feeders made from SA106 grade B low alloy carbon-steel (with chromium at 0.02%). CFD method is used in this paper to investigate the feeder's wall thinning process taking place mainly due local flow conditions in complex 3D geometrical configurations. The 380 outlet feeders grouped in 2.5'' (320) and 2.0'' feeders (60). The objective of this paper is to help, as much as possible, to focus investigation on most probable maximum thinning rate locations through 3D distribution of some TH parameters. Application of CFD methods in CANDU6 nuclear reactors implies the knowledge of real plant operating data like: long term time averaged channel power and mass flow as well as temperature, pressure, pHa etc allowing the optimization and cost reduction of wall thinning monitoring process at CANDU6 nuclear power plants. (authors)

  10. A bend thickness sensitivity study of Candu feeder piping

    International Nuclear Information System (INIS)

    Li, M.; Aggarwal, M.L.; Meysner, A.; Micelotta, C.

    2005-01-01

    In CANDU reactors, feeder bends close to the connection at the fuel channel may be subjected to the highest Flow Accelerated Corrosion (FAC) and stresses. Feeder pipe stress analysis is crucial in the life extension of aging CANDU plants. Typical feeder pipes are interconnected by upper link plates and spacers. It is well known that the stresses at the bends are sensitive to the local bend thicknesses. It is also known from the authors' study (Li and et al, 2005) that feeder inter linkage effect is significant and cannot be ignored. The field measurement of feeder bend thickness is difficult and may be subjected to uncertainty in accuracy. Hence, it is desirable to know how the stress on a subject feeder could be affected by the bend thickness variation of the neighboring feeders. This effect cannot be evaluated by the traditional 'single' feeder model approach. In this paper, the 'row' and 'combined' models developed in the previous study (Li and et al, 2005), which include the feeder interactions, are used to investigate the sensitivity of bend thickness. A series of random thickness bounded by maximum and minimum measured values were applied to feeders in the model. The results show that an individual feeder is not sensitive to the bend thickness variation of the remaining feeders in the model, but depends primarily on its own bend thickness. The highest stress at a feeder always occurs when the feeder has the smallest possible bend thickness. A minimum acceptable bend thickness for individual feeders can be computed by an iterative computing process. The dependency of field thickness measurement and the amount of required analysis work can be greatly reduced. (authors)

  11. Pressurized feeder for biofuels; Paineistettu syoetin biopolttoaineille

    Energy Technology Data Exchange (ETDEWEB)

    Lundqvist, R; Makkonen, P [Foster Wheeler Energia Oy, Karhula (Finland). Karhula R and D Center

    1996-12-31

    A new type of pressurized piston feeder has been tested for further development of the IGCC concept. The project is funded by the Finnish Ministry of Trade and Industry. The objective has been to develop a substitute for lock-hopper systems, which are commercial, but far too expensive from an operational point of view, due to high inert gas consumption for pressurization. The new feeder system, which is of dual piston type, uses little inert gas, because the pressurization sequence is performed partially by the piston movement. The project comprised further development of the concept, mechanical testing under atmospheric and pressurized conditions and testing with wood chips, peat and coal at elevated pressures. The main concern has been the wear of seals and gaskets during long term operation and for this reason over 600 hours of testing has been carried out. The tests were carried out between May 1994 and January 1995 with wood chips, peat and coal mainly at 17 bar(a) pressure. During the operation, the system was fine-tuned, and generally, the testing was successful. At the early stage of the tests, the ring seal design was modified and several alternative seal constructions were tested. During the tests, the seal was developed further and improved. The present ring seal design has been proven reliable and it meets the commercial requirements. After the tests, the feeder system was inspected thoroughly and found to be in good condition. A commercially available concept of the feeder has been developed on the basis of the knowledge obtained during the test runs

  12. Pressurized feeder for biofuels; Paineistettu syoetin biopolttoaineille

    Energy Technology Data Exchange (ETDEWEB)

    Lundqvist, R.; Makkonen, P. [Foster Wheeler Energia Oy, Karhula (Finland). Karhula R and D Center

    1995-12-31

    A new type of pressurized piston feeder has been tested for further development of the IGCC concept. The project is funded by the Finnish Ministry of Trade and Industry. The objective has been to develop a substitute for lock-hopper systems, which are commercial, but far too expensive from an operational point of view, due to high inert gas consumption for pressurization. The new feeder system, which is of dual piston type, uses little inert gas, because the pressurization sequence is performed partially by the piston movement. The project comprised further development of the concept, mechanical testing under atmospheric and pressurized conditions and testing with wood chips, peat and coal at elevated pressures. The main concern has been the wear of seals and gaskets during long term operation and for this reason over 600 hours of testing has been carried out. The tests were carried out between May 1994 and January 1995 with wood chips, peat and coal mainly at 17 bar(a) pressure. During the operation, the system was fine-tuned, and generally, the testing was successful. At the early stage of the tests, the ring seal design was modified and several alternative seal constructions were tested. During the tests, the seal was developed further and improved. The present ring seal design has been proven reliable and it meets the commercial requirements. After the tests, the feeder system was inspected thoroughly and found to be in good condition. A commercially available concept of the feeder has been developed on the basis of the knowledge obtained during the test runs

  13. Improvement of automatic fish feeder machine design

    Science.gov (United States)

    Chui Wei, How; Salleh, S. M.; Ezree, Abdullah Mohd; Zaman, I.; Hatta, M. H.; Zain, B. A. Md; Mahzan, S.; Rahman, M. N. A.; Mahmud, W. A. W.

    2017-10-01

    Nation Plan of action for management of fishing is target to achieve an efficient, equitable and transparent management of fishing capacity in marine capture fisheries by 2018. However, several factors influence the fishery production and efficiency of marine system such as automatic fish feeder machine could be taken in consideration. Two latest fish feeder machines have been chosen as the reference for this study. Based on the observation, it has found that the both machine was made with heavy structure, low water and temperature resistance materials. This research’s objective is to develop the automatic feeder machine to increase the efficiency of fish feeding. The experiment has conducted to testing the new design of machine. The new machine with maximum storage of 5 kg and functioning with two DC motors. This machine able to distribute 500 grams of pellets within 90 seconds and longest distance of 4.7 meter. The higher speed could reduce time needed and increase the distance as well. The minimum speed range for both motor is 110 and 120 with same full speed range of 255.

  14. Feeder density enhances house finch disease transmission in experimental epidemics.

    Science.gov (United States)

    Moyers, Sahnzi C; Adelman, James S; Farine, Damien R; Thomason, Courtney A; Hawley, Dana M

    2018-05-05

    Anthropogenic food provisioning of wildlife can alter the frequency of contacts among hosts and between hosts and environmental sources of pathogens. Despite the popularity of garden bird feeding, few studies have addressed how feeders influence host contact rates and disease dynamics. We experimentally manipulated feeder density in replicate aviaries containing captive, pathogen-naive, groups of house finches ( Haemorhous mexicanus ) and continuously tracked behaviours at feeders using radio-frequency identification devices. We then inoculated one bird per group with Mycoplasma gallisepticum (Mg), a common bacterial pathogen for which feeders are fomites of transmission, and assessed effects of feeder density on house finch behaviour and pathogen transmission. We found that pathogen transmission was significantly higher in groups with the highest density of bird feeders, despite a significantly lower rate of intraspecific aggressive interactions relative to the low feeder density groups. Conversely, among naive group members that never showed signs of disease, we saw significantly higher concentrations of Mg-specific antibodies in low feeder density groups, suggesting that birds in low feeder density treatments had exposure to subclinical doses of Mg. We discuss ways in which the density of garden bird feeders could play an important role in mediating the intensity of Mg epidemics.This article is part of the theme issue 'Anthropogenic resource subsidies and host-parasite dynamics in wildlife'. © 2018 The Author(s).

  15. Risk-informed prediction of feeder end of life

    International Nuclear Information System (INIS)

    Jyrkama, M.; Pandey, M.

    2011-01-01

    The operating life of feeder piping is negatively impacted by flow accelerated corrosion (FAC). In this study, an assessment of a large set of inspection data reveals that FAC in feeders is a relatively stationary process, with variability only at the local scale. Given the added uncertainty from inspection coverage, a new method for estimating the thinning rate and feeder EOL is developed using a probabilistic approach. The results of the study illustrate the benefits of the methodology in supporting risk-informed decision making at the station by quantifying the present and incremental risk in the feeder system over time. (author)

  16. Determination of representative CANDU feeder dimensions for engineering simulator

    International Nuclear Information System (INIS)

    Cho, S.; Muzumdar, A.

    1996-01-01

    This paper describes a logic for selection of representative channel groups and a methodology for determination of representative CANDU feeder dimensions and the pressure drops between inlet/outlet header and fuel channel in the primary loop. A code, MEDOC, was developed based on this logic and methodology and helps perform a calculation of representative feeder dimensions for a selected channel group on the basis of feeder geometry data (fluid volume, mass flow rate, loss factor) and given property data (pressure, quality, density) at inlet/outlet header. The representative feeder dimensions calculated based on this methodology will be useful for the engineering simulator for the CANDU type reactor. (author)

  17. Risk-informed prediction of feeder end of life

    Energy Technology Data Exchange (ETDEWEB)

    Jyrkama, M.; Pandey, M. [Univ. of Waterloo, Ontario (Canada)

    2011-07-01

    The operating life of feeder piping is negatively impacted by flow accelerated corrosion (FAC). In this study, an assessment of a large set of inspection data reveals that FAC in feeders is a relatively stationary process, with variability only at the local scale. Given the added uncertainty from inspection coverage, a new method for estimating the thinning rate and feeder EOL is developed using a probabilistic approach. The results of the study illustrate the benefits of the methodology in supporting risk-informed decision making at the station by quantifying the present and incremental risk in the feeder system over time. (author)

  18. BC Hydro's integrated approach on replacing underground feeder cables

    Energy Technology Data Exchange (ETDEWEB)

    Tarampi, D. [BC Hydro, Burnaby, BC (Canada)

    2008-07-01

    BC Hydro's integrated approach on replacing underground feeder cables was discussed. The feeder cables were all in ducts encased in concrete and splices were identified in concrete manholes. The feeder cables averaged 35 to 40 failures per year, with a large majority of failures occurring in manholes or near terminations. The age of the cables was not known. A graphical representation of a condition assessment was presented with reference to an electrical test, metallurgical test, hardness test, and dye penetrating test. Prioritization steps were also listed, including a condition index and replacement threshold. Steps in prioritizing the condition index included determining the insulation index based on electrical test results; determining the manhole condition based on metallurgical test results; determining the customer importance factor and feeder load factor; and calculating the overall condition index based on the indices. A process flowchart was also illustrated. A replacement strategy was then discussed and a cost comparison of two options was described. Option 1 was to replace only the unjacketed cables while option two involved selective replacement. tabs., figs.

  19. 26 CFR 1.502-1 - Feeder organizations.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Feeder organizations. 1.502-1 Section 1.502-1...) INCOME TAXES (CONTINUED) Exempt Organizations § 1.502-1 Feeder organizations. (a) In the case of an organization operated for the primary purpose of carrying on a trade or business for profit, exemption is not...

  20. Colour preferences of UK garden birds at supplementary seed feeders.

    Directory of Open Access Journals (Sweden)

    Luke Rothery

    Full Text Available Supplementary feeding of garden birds generally has benefits for both bird populations and human wellbeing. Birds have excellent colour vision, and show preferences for food items of particular colours, but research into colour preferences associated with artificial feeders is limited to hummingbirds. Here, we investigated the colour preferences of common UK garden birds foraging at seed-dispensing artificial feeders containing identical food. We presented birds simultaneously with an array of eight differently coloured feeders, and recorded the number of visits made to each colour over 370 30-minute observation periods in the winter of 2014/15. In addition, we surveyed visitors to a garden centre and science festival to determine the colour preferences of likely purchasers of seed feeders. Our results suggest that silver and green feeders were visited by higher numbers of individuals of several common garden bird species, while red and yellow feeders received fewer visits. In contrast, people preferred red, yellow, blue and green feeders. We suggest that green feeders may be simultaneously marketable and attractive to foraging birds.

  1. Development of ceramic-free antenna feeder

    International Nuclear Information System (INIS)

    Moriyama, S.; Kimura, H.; Fujii, T.; Saigusa, M.; Arai, H.

    1994-01-01

    We have proposed a ceramics-free antenna feeder line employing a ridged waveguide as a local support for IC antenna of next-generation tokamaks. One fourth mock-up model of the all metal waveguide designed for the ITER ICRF system is fabricated and electrical characteristics of the model including the coaxial line - waveguide converter are measured. Power reflection coefficient of the model including the coax-waveguide converter to the input coaxial line is estimated to be less than 15% below the cut-off frequency of 107 MHz and less than 3% above the cut-off frequency. It is found that this ceramics-free antenna support employing a ridged waveguide is quite available for IC antenna of next-generation tokamaks. (author)

  2. Real-Time Distribution Feeder Performance Monitoring, Advisory Control, and Health Management System

    Energy Technology Data Exchange (ETDEWEB)

    Stoupis, James; Mousavi, Mirrasoul

    2014-09-30

    provides this time and helps accelerate service restoration ultimately. To demonstrate the effectiveness of this feature, a demo system using substation data alone was set up to compare the minutes saved over a period of 22 months for two feeders where the real-time notification system has been deployed. The metric used for performance assessment is the time difference between the actual outage time from the OMS versus the time the notification email was received on the operators desk. Over the period of 22 months, we have accumulated over 7600 minutes (32 hours) ahead of actual outage time compared to the OMS timestamps. The significance of this analysis is that it shows the potential to reduce the SAIDI minutes and directly impact utility performance in terms of outage duration. If deployed at scale, it would have a significant impact on system reliability. To put this number in perspective, it would be helpful to assign a dollar figure to the potential savings that could be realized. According to the host utility, the average cost for each customer-minute-out (CMO) is approximately $0.30 across the operating company. This includes both direct and indirect costs such as bad press. The outage data over the previous 4 years show that the average customer count on primary/tap level outages is about 56. Accordingly, the total minutes saved amounts to 425,600 CMOs on the average. This would in turn result in a potential cost savings figure of $127,680 for two feeders alone over the period of performance. This empirical evidence validates the strong value proposition of the project that was contemplated at the onset and its potential impact to reduce outage duration in support of DOE’s goal of 20%

  3. A Dynamic and Heuristic Phase Balancing Method for LV Feeders

    Directory of Open Access Journals (Sweden)

    Samad Taghipour Boroujeni

    2016-01-01

    Full Text Available Due to the single-phase loads and their stochastic behavior, the current in the distribution feeders is not balanced. In addition, the single-phase loads are located in different positions along the LV feeders. So the amount of the unbalanced load and its location affect the feeder losses. An unbalanced load causes the feeder losses and the voltage drop. Because of time-varying behavior of the single-phase loads, phase balancing is a dynamic and combinatorial problem. In this research, a heuristic and dynamic solution for the phase balancing of the LV feeders is proposed. In this method, it is supposed that the loads’ tie could be connected to all phases through a three-phase switch. The aim of the proposed method is to make the feeder conditions as balanced as possible. The amount and the location of single-phase loads are considered in the proposed phase balancing method. Since the proposed method needs no communication interface or no remote controller, it is inexpensive, simple, practical, and robust. Applying this method provides a distributed and dynamic phase balancing control. In addition, the feasibility of reducing the used switches is investigated. The ability of the proposed method in the phase balancing of the LV feeders is approved by carrying out some simulations.

  4. Human induced pluripotent stem cells on autologous feeders.

    Directory of Open Access Journals (Sweden)

    Kazutoshi Takahashi

    Full Text Available BACKGROUND: For therapeutic usage of induced Pluripotent Stem (iPS cells, to accomplish xeno-free culture is critical. Previous reports have shown that human embryonic stem (ES cells can be maintained in feeder-free condition. However, absence of feeder cells can be a hostile environment for pluripotent cells and often results in karyotype abnormalities. Instead of animal feeders, human fibroblasts can be used as feeder cells of human ES cells. However, one still has to be concerned about the existence of unidentified pathogens, such as viruses and prions in these non-autologous feeders. METHODOLOGY/PRINCIPAL FINDINGS: This report demonstrates that human induced Pluripotent Stem (iPS cells can be established and maintained on isogenic parental feeder cells. We tested four independent human skin fibroblasts for the potential to maintain self-renewal of iPS cells. All the fibroblasts tested, as well as their conditioned medium, were capable of maintaining the undifferentiated state and normal karyotypes of iPS cells. Furthermore, human iPS cells can be generated on isogenic parental fibroblasts as feeders. These iPS cells carried on proliferation over 19 passages with undifferentiated morphologies. They expressed undifferentiated pluripotent cell markers, and could differentiate into all three germ layers via embryoid body and teratoma formation. CONCLUSIONS/SIGNIFICANCE: These results suggest that autologous fibroblasts can be not only a source for iPS cells but also be feeder layers. Our results provide a possibility to solve the dilemma by using isogenic fibroblasts as feeder layers of iPS cells. This is an important step toward the establishment of clinical grade iPS cells.

  5. A Decentralized Storage Strategy for Residential Feeders with Photovoltaics

    DEFF Research Database (Denmark)

    Marra, Francesco; Yang, Guangya; Træholt, Chresten

    2014-01-01

    . The power sizing of the ESSs is performed with linear programming (LP) method, based on voltage sensitivity analysis. A Belgian residential LV feeder with private PV systems is used as a case study to demonstrate the effectiveness of the proposed strategy. Quantification of the required energy levels...... domestic energy storage systems (ESS). The traditional way of operating a domestic ESS to increase the local consumption rate does not take into account the need of voltage support in a feeder; the proposed storage concept improves the traditional one, by mitigating voltage rise due to PV in the feeder...

  6. Automation Selection and Sequencing of Traps for Vibratory Feeders

    DEFF Research Database (Denmark)

    Mathiesen, Simon; Ellekilde, Lars-Peter

    2017-01-01

    Vibratory parts feeders with mechanical orienting devices are used extensively in the assembly automation industry. Even so, the design process is based on trial-and-error approaches and is largely manual. In this paper, a methodology is presented for automatic design of this type of feeder....... The approach uses dynamic simulation for generating the necessary data for configuring a feeder with a sequence of mechanical orienting devices called traps, with the goal of reorienting all parts from a random to fixed orientation. Then, a fast algorithm for facilitating this configuration task automatically...

  7. Damping considerations in CANDU feeder pipe design and analysis

    International Nuclear Information System (INIS)

    Usmani, S.A.; Saleem, M.A.; So, G.

    1990-01-01

    Recent developments in pipe damping indicate a trend towards more realistic and less conservative values, which result in less rigid and safer pipe designs. The CANDU-PHW (Canada deuterium uranium, pressurized heavy water) reactor feeder pipe designs have applied similar approaches which permit seismic qualifications without overly restraining these compact arrays of pipes to cater for the large creep and thermal anchor movement. This paper reviews the feeder design aspects, especially pertaining to the design provisions, experimental verification and analytical modelling for seismic qualification in the light of recent pipe dynamic developments. Using illustrative examples, comparison of seismic analysis results is provided for the ASME Code Case N-411 dampings, and those traditionally used in the feeder seismic qualification. The results confirm acceptability of the traditional approach which permit simplified analysis to demonstrate seismic qualificationqualification of CANDU feeder pipes

  8. Faecal nitrogen of browser and mixed feeder game species during ...

    African Journals Online (AJOL)

    Faecal nitrogen of browser and mixed feeder game species during different seasons. ... A practical measure of assessing periods of potential nutritional stress of game species is needed in the management of ... AJOL African Journals Online.

  9. Structural integrity investigations of feeder pipe ice plugging procedures

    International Nuclear Information System (INIS)

    Flaman, M.T.; Shah, N.N.

    1985-03-01

    A procedure involving the use of a liquid nitrogen cooled heat exchanger to form internal ice plugs in feeder pipes is routinely used in nuclear generating stations. The use of this procedure has caused concerns with regard to the safety of station maintenance personnel, and in regard to the integrity of the feeder pipes. This report describes the results of laboratory stress and pressure measurements which were performed on a feeder pipe section during ice plugging operations to investigate these concerns. From the results of this study, and from the results of previous studies of material behaviour at low temperatures, it has been determined that the ice plugging procedure can be performed on feeder pipes in a safe and effective manner

  10. SAFIRE - a robotic inspection system for CANDU feeders

    International Nuclear Information System (INIS)

    Buckingham, R.

    2011-01-01

    The condition of primary circuit feeder pipes in CANDU reactors is relevant to the commercial viability and plant life. One known wear mechanism is external fretting between feeder pipes and adjacent services or support structures, particularly within the Upper Feeder Cabinet (UFC). Fretting leads to wall thinning which must not exceed certain agreed limits. Chafe shields have been added to protect the feeder pipes. Regular inspections are required of the chafe shields, feeder pipes and other structures that may cause feeder damage. Historically, the dose received by inspectors conducting this work has been significant. For this reason Ontario Power Generation has invested in a remotely operated robot system to conduct visual inspections within the UFC. This system, called SAFIRE for 'Snake-Arm Feeder Inspection Robot Equipment' has been deployed at Pickering during 2010 and 2011 and has been used to inspect areas that are extremely difficult to inspect with existing manual techniques. The 2011 scope of work included inspection of a total of 660 feeder pipes in three UFC quadrants, in two reactors. The full scope was completed over a one-month period in Autumn 2011 in which SAFIRE was used during 23, twelve hour shifts. This included two periods each of 72 hours of continuous operation using multiple teams of operators. SAFIRE is remote controlled delivery system for multiple cameras to record still images and video. The main system elements include a snake-arm robot mounted on a mobile vehicle. It can be controlled from up to 500m away using a fibre/copper connection. The snake-arm is 2.2m long, 25mm wide and has 18 degrees of freedom. It is designed to snake between the rows of feeder pipes to inspect feeder/hanger interfaces, both above and below the feeder cabinet catwalks. Future upgrades offer the potential to add additional tools to increase functionality. This paper describes the SAFIRE development process from inception to operational experience gained

  11. SAFIRE - a robotic inspection system for CANDU feeders

    Energy Technology Data Exchange (ETDEWEB)

    Buckingham, R. [OC Robotics, Bristol (United Kingdom)

    2011-07-01

    The condition of primary circuit feeder pipes in CANDU reactors is relevant to the commercial viability and plant life. One known wear mechanism is external fretting between feeder pipes and adjacent services or support structures, particularly within the Upper Feeder Cabinet (UFC). Fretting leads to wall thinning which must not exceed certain agreed limits. Chafe shields have been added to protect the feeder pipes. Regular inspections are required of the chafe shields, feeder pipes and other structures that may cause feeder damage. Historically, the dose received by inspectors conducting this work has been significant. For this reason Ontario Power Generation has invested in a remotely operated robot system to conduct visual inspections within the UFC. This system, called SAFIRE for 'Snake-Arm Feeder Inspection Robot Equipment' has been deployed at Pickering during 2010 and 2011 and has been used to inspect areas that are extremely difficult to inspect with existing manual techniques. The 2011 scope of work included inspection of a total of 660 feeder pipes in three UFC quadrants, in two reactors. The full scope was completed over a one-month period in Autumn 2011 in which SAFIRE was used during 23, twelve hour shifts. This included two periods each of 72 hours of continuous operation using multiple teams of operators. SAFIRE is remote controlled delivery system for multiple cameras to record still images and video. The main system elements include a snake-arm robot mounted on a mobile vehicle. It can be controlled from up to 500m away using a fibre/copper connection. The snake-arm is 2.2m long, 25mm wide and has 18 degrees of freedom. It is designed to snake between the rows of feeder pipes to inspect feeder/hanger interfaces, both above and below the feeder cabinet catwalks. Future upgrades offer the potential to add additional tools to increase functionality. This paper describes the SAFIRE development process from inception to operational experience

  12. Urban Bird Feeders Dominated by a Few Species and Individuals

    Directory of Open Access Journals (Sweden)

    Josie A. Galbraith

    2017-08-01

    Full Text Available The practice of garden bird feeding is a global phenomenon, involving millions of people and vast quantities of food annually. Many people engage in the practice of feeding assuming that birds gain some benefit from the food they provide, yet recent studies have revealed the potential for detrimental impacts as well. However, there is still a paucity of information on the impacts of feeding, including the ubiquity of these impacts among and within feeder-visiting species. Consistency in feeder use among birds is likely an important determinant of this. Individual birds and species that make frequent use of feeders are more likely to experience both the benefits and detrimental impacts of supplementary food. We investigated patterns of feeder use by garden birds visiting experimental feeding stations in Auckland, New Zealand, with the specific aim of determining whether use of supplementary food was consistent or variable among individuals and species. We used camera traps as well as Radio Frequency Identification (RFID technology to examine intra- and interspecific feeder visitation patterns and to discern species associations. Eleven bird species were detected using feeding stations, however, two introduced species (house sparrow Passer domesticus and spotted dove Streptopelia chinensis dominated visitation events. These species were present at feeders most frequently, with the largest conspecific group sizes. Significant associations were detected among a number of species, suggesting interspecific interactions are important in determining feeder use. We also found within-species differences in feeder use for all focal species, with individual variation greatest in house sparrows. Furthermore, season had an important influence on most visitation parameters. The observed individual and species-specific differences in supplementary food resource use imply that the impacts of garden bird feeding are not universal. Crucially, particularly given

  13. Neural stem cells achieve and maintain pluripotency without feeder cells.

    Directory of Open Access Journals (Sweden)

    Hyun Woo Choi

    Full Text Available BACKGROUND: Differentiated cells can be reprogrammed into pluripotency by transduction of four defined transcription factors. Induced pluripotent stem cells (iPS cells are expected to be useful for regenerative medicine as well as basic research. Recently, the report showed that mouse embryonic fibroblasts (MEF cells are not essential for reprogramming. However, in using fibroblasts as donor cells for reprogramming, individual fibroblasts that had failed to reprogram could function as feeder cells. METHODOLOGY/PRINCIPAL FINDING: Here, we show that adult mouse neural stem cells (NSCs, which are not functional feeder cells, can be reprogrammed into iPS cells using defined four factors (Oct4, Sox2, Klf4, and c-Myc under feeder-free conditions. The iPS cells, generated from NSCs expressing the Oct4-GFP reporter gene, could proliferate for more than two months (passage 20. Generated and maintained without feeder cells, these iPS cells expressed pluripotency markers (Oct4 and Nanog, the promoter regions of Oct4 and Nanog were hypomethylated, could differentiated into to all three germ layers in vitro, and formed a germline chimera. These data indicate that NSCs can achieve and maintain pluripotency under feeder-free conditions. CONCLUSION/SIGNIFICANCE: This study suggested that factors secreted by feeder cells are not essential in the initial/early stages of reprogramming and for pluripotency maintenance. This technology might be useful for a human system, as a feeder-free reprogramming system may help generate iPS cells of a clinical grade for tissue or organ regeneration.

  14. Assessment of CANDU feeders subject to flow accelerated corrosion

    Energy Technology Data Exchange (ETDEWEB)

    Iyer, S. [Atomic Energy of Canada Ltd., Mississauga, Ontario (Canada); Slade, J.P. [New Brunswick Power, Point Lepreau Generating Station, Lepreau, New Brunswick (Canada)

    2003-07-01

    'Full Text:' Inspections of CANDU feeders have indicated greater than expected wall thinning of outlet feeders. This wall thinning is attributed to Flow-Accelerated Corrosion (FAC). The rate of wall loss due to FAC is highest in the close radius bends near the end fitting. The minimum allowed thickness for a feeder pipes is based on design pressure during the design stage. Extended operation of the thinned feeders beyond their design basis, i.e., operation of feeders with thickness below design pressure based minimum thickness has economic benefits for the utilities. In such cases, it is important to establish the remaining life and evaluate the adequacy of the components for safe operation. ASME Code Case N-597 provides the guidelines for acceptance for continued service of Classes 2 and 3 piping components experiencing wall thinning during operation. However, for Class 1 systems, the Code Case recommends that the owner develop the methodology and criteria for the assessment of wall thinning. Therefore, under the CANDU Owner's Group's (COG) Feeder Integrity Joint Program (FIJP), the 'Fitness for Service Guidelines (FFSG) for Feeders Affected by Wall Thinning in Operating CANDU Reactors' was developed and subsequently conditionally approved by CNSC. This paper illustrates the underlying concepts in the FFSG methodology and its benefits to utilities. Specific examples of the application and benefits of the FFSG at Point Lepreau G.S. are described in this paper. The assessment of feeders is based on the requirements of the construction Code (Section III of the ASME Boiler and Pressure Vessel Code): The following points briefly describe the assessment methodology. Satisfying the requirements of NB-3650 for design and service loadings are sufficient for continued service and extended life if the predicted minimum wall thickness of the component is greater than or equal to 90% of the pressure based thickness calculated as per NB-3641. The B

  15. Object categorization by wild ranging birds-Winter feeder experiments.

    Science.gov (United States)

    Nováková, Nela; Veselý, Petr; Fuchs, Roman

    2017-10-01

    The object categorization is only scarcely studied using untrained wild ranging animals and relevant stimuli. We tested the importance of the spatial position of features salient for categorization of a predator using wild ranging birds (titmice) visiting a winter feeder. As a relevant stimulus we used a dummy of a raptor, the European sparrowhawk (Accipiter nisus), placed at the feeding location. This dummy was designed to be dismantled into three parts and rearranged with the head in the correct position, in the middle or at the bottom of the dummy. When the birds had the option of visiting an alternative feeder with a dummy pigeon, they preferred this option to visiting the feeder with the dummy sparrowhawk with the head in any of the three positions. When the birds had the option of visiting an alternative feeder with an un-rearranged dummy sparrowhawk, they visited both feeders equally often, and very scarcely. This suggests that the titmice considered all of the sparrowhawk modifications as being dangerous, and equally dangerous as the un-rearranged sparrowhawk. The position of the head was not the most important cue for categorization. The presence of the key features was probably sufficient for categorization, and their mutual spatial position was of lower importance. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Seismic analysis of ITER fourth PF (Poloidal Field Coil) feeder

    International Nuclear Information System (INIS)

    Liu, Sumei; Chen, Wei; Song, Yuntao; Ni, Xiaojun; Wang, Zhongwei; Chen, Yonghua; Gong, Chenyu

    2014-01-01

    The ITER feeder systems connect the ITER magnet systems located inside the main cryostat to the cryo-plant, power-supply and control system interfaces outside the cryostat. The main purpose of the feeders is to convey the cryogenic supply and electrical power to the coils as well as house the instrumentation wiring. The PF busbar which carries 52 kA current will suffer from high Lorentz force due to the background magnetic field inspired by the coils and the self-field between every pair of busbars. Except their mechanical strength and thermal insulation performance must be achieved, the dynamic mechanism on PF structure should be assessed. This paper presents the simulation and seismic analysis on ITER 4th PF feeder including the Coil Terminal Box and S-bend Box (CTB and SBB), the Cryostat Feed-through (CFT), the In-Cryostat-Feeder (ICF), especially for the ground supports and main outer-tube firstly. This analysis aims to study seismic resistance on system design under local seismograms with floor response spectrum, the structural response vibration mode and response duration results of displacement, membrane stress, and bending stress on structure under different directions actuating signals were obtained by using the single-seismic spectrum analysis and Dead Weight analysis respectively. Based on the simulative and analytical results, the system seismic resistance and the integrity of the support structure in the 4th PF feeder have been studied and the detail design confirmed

  17. A New Optimization Framework To Solve The Optimal Feeder Reconfiguration And Capacitor Placement Problems

    Directory of Open Access Journals (Sweden)

    Mohammad-Reza Askari

    2015-07-01

    Full Text Available Abstract This paper introduces a new stochastic optimization framework based bat algorithm BA to solve the optimal distribution feeder reconfiguration DFR as well as the shunt capacitor placement and sizing in the distribution systems. The objective functions to be investigated are minimization of the active power losses and minimization of the total network costs an. In order to consider the uncertainties of the active and reactive loads in the problem point estimate method PEM with 2m scheme is employed as the stochastic tool. The feasibility and good performance of the proposed method are examined on the IEEE 69-bus test system.

  18. A Markov chain model for CANDU feeder pipe degradation

    International Nuclear Information System (INIS)

    Datla, S.; Dinnie, K.; Usmani, A.; Yuan, X.-X.

    2008-01-01

    There is need for risk based approach to manage feeder pipe degradation to ensure safe operation by minimizing the nuclear safety risk. The current lack of understanding of some fundamental degradation mechanisms will result in uncertainty in predicting the rupture frequency. There are still concerns caused by uncertainties in the inspection techniques and engineering evaluations which should be addressed in the current procedures. A probabilistic approach is therefore useful in quantifying the risk and also it provides a tool for risk based decision making. This paper discusses the application of Markov chain model for feeder pipes in order to predict and manage the risks associated with the existing and future aging-related feeder degradation mechanisms. The major challenge in the approach is the lack of service data in characterizing the transition probabilities of the Markov model. The paper also discusses various approaches in estimating plant specific degradation rates. (author)

  19. Configuration System for Simulation Based Design of Vibratory Bowl Feeders

    DEFF Research Database (Denmark)

    Hansson, Michael Natapon; Mathiesen, Simon; Ellekilde, Lars-Peter

    2017-01-01

    Vibratory bowl feeders are still among the most commonly used production equipment for automated part feeding, where parts are correctly oriented for further manipulation by being conveyed through a set of orienting devices. Designing vibratory bowl feeders involves selecting and sequencing...... a number of these devices that either reorients or rejects the part until a desirable orientation is achieved. To aid the designer in this task, this work presents a configuration system where knowledge of the behaviour for each device is acquired through dynamic simulation, and used to solve...

  20. Microplastic in a macro filter feeder: humpback whale Megaptera novaeangliae

    NARCIS (Netherlands)

    Besseling, E.; Foekema, E.M.; Franeker, van J.A.; Leopold, M.F.; Bravo Rebolledo, E.; Kuehn, S.; Mielke, L.; Heberle-Bors, E.; Ijzer, J.; Kamminga, P.; Koelmans, A.A.

    2015-01-01

    Marine filter feeders are exposed to microplastic because of their selection of small particles as food source. Baleen whales feed by filtering small particles from large water volumes. Macroplastic was found in baleen whales before. This study is the first to show the presence of microplastic in

  1. Optimisation of Trap Design for Vibratory Bowl Feeders

    DEFF Research Database (Denmark)

    Mathiesen, Simon; Sørensen, Lars Carøe; Kraft, Dirk

    2018-01-01

    Vibratory bowl feeders (VBFs) are a widely used option for industrial part feeding, but their design is still largely manual. A subtask of VBF design is determining an optimal parameter set for the passive devices, called traps, which the VBF uses to ensure correct part orientation. This paper...

  2. Microplastic in a macro filter feeder: Humpback whale Megaptera novaeangliae.

    NARCIS (Netherlands)

    E., Besseling,; E.M., Foekema,; J.A. van, Franeker; Leopold, Mardik F; Kuhn, S.; Bravo Rebolledo, E.L.; Hese, E.; Mielke, L.; IJzer, J.|info:eu-repo/dai/nl/304839663; Kamminga, P.; Koelmans, A.A.

    2015-01-01

    Marine filter feeders are exposed to microplastic because of their selection of small particles as food source. Baleen whales feed by filtering small particles from large water volumes. Macroplastic was found in baleen whales before. This study is the first to show the presence of microplastic in

  3. A hybrid evolutionary algorithm for distribution feeder reconfiguration

    Indian Academy of Sciences (India)

    the reconfiguration of distribution networks has been proposed by .... An effective strategy to increase the loading margin of heavily loaded feeders is to ... social animals such as a flock of birds, a school of fish or a group of people that pursue.

  4. Novel Methods to Determine Feeder Locational PV Hosting Capacity and PV Impact Signatures

    Energy Technology Data Exchange (ETDEWEB)

    Reno, Matthew J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Coogan, Kyle [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Seuss, John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Broderick, Robert Joseph [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-05-01

    Often PV hosting capacity analysis is performed for a limited number of distribution feeders. For medium - voltage distribution feeders, previous results generally analyze less than 20 feeders, and then the results are extrapolated out to similar types of feeders. Previous hosting capacity research has often focused on determining a single value for the hosting capacity for the entire feeder, whereas this research expands previous hosting capacity work to investigate all the regions of the feeder that may allow many different hosting capacity values wit h an idea called locational hosting capacity (LHC)to determine the largest PV size that can be interconnected at different locations (buses) on the study feeders. This report discusses novel methods for analyzing PV interconnections with advanced simulati on methods. The focus is feeder and location - specific impacts of PV that determine the locational PV hosting capacity. Feeder PV impact signature are used to more precisely determine the local maximum hosting capacity of individual areas of the feeder. T he feeder signature provides improved interconnection screening with certain zones that show the risk of impact to the distribution feeder from PV interconnections.

  5. Power Hardware-in-the-Loop Evaluation of PV Inverter Grid Support on Hawaiian Electric Feeders: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, Austin; Prabakar, Kumaraguru; Nagarajan, Adarsh; Nepal, Shaili; Hoke, Anderson; Asano, Marc; Ueda, Reid; Ifuku, Earle

    2017-05-08

    As more grid-connected photovoltaic (PV) inverters become compliant with evolving interconnections requirements, there is increased interest from utilities in understanding how to best deploy advanced grid-support functions (GSF) in the field. One efficient and cost-effective method to examine such deployment options is to leverage power hardware-in-the-loop (PHIL) testing methods. Two Hawaiian Electric feeder models were converted to real-time models in the OPAL-RT real-time digital testing platform, and integrated with models of GSF capable PV inverters that were modeled from characterization test data. The integrated model was subsequently used in PHIL testing to evaluate the effects of different fixed power factor and volt-watt control settings on voltage regulation of the selected feeders. The results of this study were provided as inputs for field deployment and technical interconnection requirements for grid-connected PV inverters on the Hawaiian Islands.

  6. Feeding Against Gravity with Spot Feeders in High Silicon Ductile Iron

    DEFF Research Database (Denmark)

    Vedel-Smith, Nikolaj Kjelgaard; Tiedje, Niels Skat

    2014-01-01

    and classified using X-ray imaging and ultrasound analysis. The effect of the different feeder configurations were classified in reference to defect location, sleeve material, and feeder type, modulus, and location. The analysis showed that exothermal feeder sleeves with the right configurations can feed up......-hill against gravity. This effect may contribute to the thermal expansion created by the exothermal reaction. It was also found that the optimum feeder size does not scale linearly with the casting modulus but that larger casting modulus requires relatively smaller modulus feeders. The thermal gradient created...

  7. Improvement of the auto wire feeder machine in a de-soldering process

    Directory of Open Access Journals (Sweden)

    Niramon Nonkhukhetkhong

    2016-10-01

    Full Text Available This paper presents the methodology of the de-soldering process for rework of disk drive Head Stack Assembly (HSA units. The auto wire feeder is a machine that generates Tin (Sn on the product. This machine was determined to be one of the major sources of excess Sn on the HSA. The defect rate due to excess Sn is more than 30%, which leads to increased processing time and cost to perform additional cleaning steps. From process analysis, the major causes of excess Sn are as follows: 1 The machine cannot cut the wire all the way into the flux core area; 2 The sizes and types of soldering irons are not appropriate for the unit parts; and, 3 There are variations introduced into the de-soldering process by the workforce. This paper proposes a methodology to address all three of these causes. First, the auto wire feeder machine in the de-solder process will be adjusted in order to cut wires into flux core. Second, the types of equipment and material used in de-soldering will be optimized. Finally, a new standard method for operators, which can be controlled more easily, will be developed in order to reduce defects due to workforce related variation. After these process controls and machine adjustments were implemented, the overall Sn related problems were significantly improved. Sn contamination was reduced by 41% and cycle time was reduced by an average of 15 seconds.

  8. Power Hardware-in-the-Loop Evaluation of PV Inverter Grid Support on Hawaiian Electric Feeders

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, Austin A [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Prabakar, Kumaraguru [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Nagarajan, Adarsh [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Nepal, Shaili [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Hoke, Anderson F [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Asano, Marc [Hawaiian Electric Company; Ueda, Reid [Hawaiian Electric Company; Ifuku, Earle [Hawaiian Electric Company

    2017-10-03

    As more grid-connected photovoltaic (PV) inverters become compliant with evolving interconnections requirements, there is increased interest from utilities in understanding how to best deploy advanced grid-support functions (GSF) in the field. One efficient and cost-effective method to examine such deployment options is to leverage power hardware-in-the-loop (PHIL) testing methods, which combine the fidelity of hardware tests with the flexibility of computer simulation. This paper summarizes a study wherein two Hawaiian Electric feeder models were converted to real-time models using an OPAL-RT real-time digital testing platform, and integrated with models of GSF capable PV inverters based on characterization test data. The integrated model was subsequently used in PHIL testing to evaluate the effects of different fixed power factor and volt-watt control settings on voltage regulation of the selected feeders using physical inverters. Selected results are presented in this paper, and complete results of this study were provided as inputs for field deployment and technical interconnection requirements for grid-connected PV inverters on the Hawaiian Islands.

  9. Feederism: an exaggeration of a normative mate selection preference?

    Science.gov (United States)

    Terry, Lesley L; Suschinsky, Kelly D; Lalumière, Martin L; Vasey, Paul L

    2012-02-01

    Quinsey and Lalumière (1995) suggested that some, if not most, paraphilias are exaggerated manifestations of more normative and functional mate selection preferences. The present study tested whether Feederism, a fat fetish focused on erotic eating, feeding, and gaining weight, is an exaggeration of a sexual arousal pattern commonly seen in the general population. Thirty participants (15 men and 15 women) recruited from the general population were assessed using penile plethysmography and vaginal photoplethysmography, respectively. None of the participants were self-identified Feeders or Feedees. Participants were shown sexual, neutral, and feeding still images while listening to audio recordings of sexual, neutral, and feeding stories. Participants did not genitally respond to feeding stimuli. However, both men and women subjectively rated feeding stimuli as more sexually arousing than neutral stimuli. We discuss the discordance between physiological and self-reported sexual arousal in the context of sex differences in sexual concordance and implications for future research.

  10. Digital optical feeder links system for broadband geostationary satellite

    Science.gov (United States)

    Poulenard, Sylvain; Mège, Alexandre; Fuchs, Christian; Perlot, Nicolas; Riedi, Jerome; Perdigues, Josep

    2017-02-01

    An optical link based on a multiplex of wavelengths at 1.55μm is foreseen to be a valuable solution for the feeder link of the next generation of high-throughput geostationary satellite. The main satellite operator specifications for such link are an availability of 99.9% over the year, a capacity around 500Gbit/s and to be bent-pipe. Optical ground station networks connected to Terabit/s terrestrial fibers are proposed. The availability of the optical feeder link is simulated over 5 years based on a state-of-the-art cloud mask data bank and an atmospheric turbulence strength model. Yearly and seasonal optical feeder link availabilities are derived and discussed. On-ground and on-board terminals are designed to be compliant with 10Gbit/s per optical channel data rate taking into account adaptive optic systems to mitigate the impact of atmospheric turbulences on single-mode optical fiber receivers. The forward and return transmission chains, concept and implementation, are described. These are based on a digital transparent on-off keying optical link with digitalization of the DVB-S2 and DVB-RCS signals prior to the transmission, and a forward error correcting code. In addition, the satellite architecture is described taking into account optical and radiofrequency payloads as well as their interfaces.

  11. A model for strategic selection of feeder management systems: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Hsing Hung [Faculty of Management and Administration, Macau University of Science and Technology, Avenue Wei Long, Taipa, Macau (China); Lee, Amy H.I. [Department of Industrial Management, Chung Hua University, No. 707, Sec. 2, Wu Fu Rd., Hsinchu 300 (China); Kang, He-Yau [Department of Industrial Engineering and Management, National Chin-Yi University of Technology, 35, Lane 215, Sec. 1, Chung San Rd., Taiping, Taichung 411 (China)

    2010-06-15

    The move to integrating distribution management system (DMS) and feeder management system (FMS) in China is becoming the main trend in recent years, in addition to upgrading and rebuilding existing energy management system (EMS) and DMS. However, with increasing complexity in the social environments along with rapidly changing technologies, how to select a suitable contractor and a FMS project is becoming an important issue for electric power companies. This paper first briefly introduces FMS and then lists its critical success criteria. A model that applies a multi-criteria decision-making (MCDM) method, an analytic network process (ANP) associated with benefits, opportunities, costs and risks (BOCR), is constructed to help power companies to select the most suitable FMS project. (author)

  12. Determinants of Cattle Feeding Profit and Cost of Gain Variability

    OpenAIRE

    Schroeder, Ted C.; Albright, Martin L.; Langemeier, Michael R.; Mintert, James R.

    1993-01-01

    Cattle feeders face risks from fluctuating fed cattle, feeder cattle, and feed prices and cattle performance. Closeout data on 7293 pens of steers are studied to determine the relative impacts of prices and animal performance on cattle feeding profits and cost of gain. Results indicate the importance of managing price risk.

  13. Some software issues in mapping of power distribution feeders

    International Nuclear Information System (INIS)

    Mufti, I.A.

    1994-01-01

    This paper is about the in-house developed software for distribution feeders mapping project. It first gives birds eye view of the project, highlight its technical complexity in management and logistics, introduced by sheer size of the project. It gives an overview of the software developed and the moves on to describe circuit tracing, circuit model, leaves isolation (for tree structured network) and backtracking in more detail among many different parts of software, description of all which is not possible because of space limitations. (author)

  14. Stress analysis of feeder bends using neutrons: new results and cumulative impacts

    Energy Technology Data Exchange (ETDEWEB)

    Banks, D.; Donaberger, R. [Canadian Neutron Beam Centre, Chalk River, ON (Canada); Leitch, B. [Atomic Energy of Canada Limited, Chalk River, ON (Canada); Rogge, R.B. [Canadian Neutron Beam Centre, Chalk River, ON (Canada)

    2014-07-01

    Neutron diffraction has played a vital role in stress analysis of bends in carbon steel pipes, known as feeder pipes, in CANDU reactors. Due to incidents of cracking of feeders, extensive R&D programs to manage feeder cracking have been implemented over about ten years. We review the cumulative impacts of this research from the view point of the stress analysis using neutrons, and present new results by examining a feeder bend with a partial crack both experimentally using neutron diffraction and theoretically using a finite element model. (author)

  15. limit loads for wall-thinning feeder pipes under combined bending and internal pressure

    International Nuclear Information System (INIS)

    Je, Jin Ho; Lee, Kuk Hee; Chung, Ha Joo; Kim, Ju Hee; Han, Jae Jun; Kim, Yun Jae

    2009-01-01

    Flow Accelerated Corrosion (FAC) during inservice conditions produces local wall-thinning in the feeder pipes of CANDU. The Wall-thinning in the feeder pipes is main degradation mechanisms affecting the integrity of piping systems. This paper discusses the integrity assessment of wall-thinned feeder pipes using limit load analysis. Based on finite element limit analyses, this paper compare limit loads for wall-thinning feeder pipes under combined bending and internal pressure with proposed limit loads. The limit loads are determined from limit analyses based on rectangular wall-thinning and elastic-perfectly-plastic materials using the large geometry change.

  16. S08: investigation and repair of a cracked feeder at Point Lepreau GS

    International Nuclear Information System (INIS)

    A Celovsky, A.; Wright, M.D.; Gendron, T.S.

    1997-01-01

    Early in 1997 investigation of a low level leak in the Point Lepreau GS (PLGS) PHTS revealed that an outlet feeder, S08, was leaking. Ultrasonic inspection, and subsequent failure analysis, revealed that the leak was a consequence of a crack. Given the unusual nature of this event, and current concerns over feeder thinning, a detailed and careful removal and examination procedure was developed. The S08 outlet feeder was removed and shipped to Chalk River Laboratories for examination. The examination confirmed that the failure was a through-wall crack, most likely the consequence of stress corrosion cracking. A critical point of the analysis was to determine how the crack initiated, and subsequently propagated. High residual stresses and possible abnormal loading in conjunction with chemistry environments resulted in the Stress Corrosion Cracking (SCC) of the S08 outlet feeder bend. It is recognized that some of the causative factors implicated in the S08 failure apply to other outlet feeders. In particular, residual stresses in the non-stress-relieved, short-radius cold bent pipes will remain relatively high over the future life of the feeders. However, the risk of CANDU feeder failure by SCC is judged to be extremely low based on the evidence of the inspections carried out to date and the good performance record of feeder pipe in the CANDU industry. The channel was restored to its locked configuration, and the failed section of feeder replaced. (author)

  17. Experience of superconducting current feeders system of SST-1

    International Nuclear Information System (INIS)

    Gupta, N.C.; Garg, A.; Sonara, D.

    2014-01-01

    The superconducting current feeder system for SST-1 which has been installed and commissioned recently along with SST-1, felicitates to energize the SST-1. The CFS consists of ten pairs of 10,000 Ampere (A) rating helium vapor cooled conventional current leads, interconnecting Cu-SC joints, three numbers of cryo-compatible SC feeders ducts, current leads assembly chamber, hydraulic network and three numbers of joint boxes operated at different current rating to charge Toroidal Field and Poloidal Field coils separately. During the last three campaigns, it was possible to achieve a controlled cool down up to 4 K and showed its rated operational performance. Actively cooled liquid nitrogen shield showed temperature profile in the temperature range of 80-85K and the whole system was evacuated up to 6x10 -6 mbar. The measured LHe consumption rates from TF VCCL were 0.3 g/s and 0.35 g/s at zero current and 1 kA respectively. (author)

  18. DYNAMICS OF VIBRATION FEEDERS WITH A NONLINEAR ELASTIC CHARACTERISTIC

    Directory of Open Access Journals (Sweden)

    V. I. Dyrda

    2017-04-01

    Full Text Available Purpose. Subject to the smooth and efficient operation of each production line, is the use of vehicles transporting high specification. It worked well in practice for transporting construction machines, which are used during the vibration. The use of vibration machines requires optimization of their operation modes. In the form of elastic link in them are increasingly using rubber-metallic elements, which are characterized by nonlinear damping properties. So it is necessary to search for new, more modern, methods of calculation of dynamic characteristics of the vibration machines on the properties of rubber as a cushioning material. Methodology. The dynamics of vibration machine that is as elastic rubber block units and buffer shock absorbers limiting the amplitude of the vibrations of the working body. The method of determining amplitude-frequency characteristics of the vibrating feeder is based on the principle of Voltaire, who in the calculations of the damping properties of the dampers will allow for elastic-hereditary properties of rubber. When adjusting the basic dynamic stiffness of the elastic ties and vibratory buffers, using the principle of heredity rubber properties, determine the dependence of the amplitude of the working body of the machine vibrations. This method is called integro-operator using the fractional-exponential kernels of relaxation. Findings. Using the derived formula for determining the amplitude of the resonance curve is constructed one-mass nonlinear system. It is established that the use of the proposed method of calculation will provide a sufficiently complete description of the damping parameters of rubber-metallic elements and at the same time be an effective means of calculating the amplitude-frequency characteristics of nonlinear vibration systems. Originality. The authors improved method of determining damping characteristics of rubber-metallic elements and the amplitude-frequency characteristics of nonlinear

  19. Response of deposit-feeders to exclusion of epibenthic predators in a Mediterranean intertidal flat

    NARCIS (Netherlands)

    Como, S.; Rossi, F.; Lardicci, C.

    2004-01-01

    Deposit-feeders are common components of macrofaunal assemblages in intertidal soft sediments. Predation has been considered to have a central role in affecting their distribution and population dynamics. This study investigates the effect of epibenthic predators on deposit-feeders, inhabiting the

  20. harmonic load modeling: a case study of 33 kv abuja steel mill feeder

    African Journals Online (AJOL)

    HOD

    techniques are adopted. This paper studied the harmonic orders of the 33 kV Abuja Steel Feeder modeled as a ... (ETAP) software package was deployed to perform Discrete Fast Transform (DFT) while the input ... and documented in research and development articles ... network with 33kV Abuja Steel feeder as case study.

  1. Final report on the evolution of supporting conditions for the feeders of 500 MWe PHWR

    International Nuclear Information System (INIS)

    Mishra, Rajesh; Soni, R.S.; Kushawaha, H.S.; Mahajan, S.C.; Kakodkar, A.; Hariprasad, K.

    1994-01-01

    This report deals with the evolution of generic supporting conditions for the feeders of 500 MWe PHWR based on the analysis and qualification of a few representative feeders. There are 196 different feeder pipe configurations for a total of 748 feeders. The present analysis was aimed at evolving a generalised supporting criteria based on the analysis of some representative feeders. The analysis was carried out for various loadings viz. pressure, temperature, dead weight, operating basis earthquake (OBE), safe shutdown earthquake (SSE) and creep loadings. The analysis for OBE and SSE loadings were carried out using response spectrum method. The effect of spacers between various feeders was modelled using higher damping values than those prescribed in ASME code. Based on the above analyses, generic supporting arrangements for the feeders of various groups have been finalized. This report gives details about the mathematical modelling, the analysis approach, the optimised supporting criteria, finalization of grouping and fixing of boundaries between various groups of feeders. (author). 34 refs., 51 figs., 69 tabs

  2. Development of I and C system for the coal feeder of coal firing plant

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Teak Soo; Park, Chan Ho [Korea Electric Power Corp. (KEPCO), Taejon (Korea, Republic of). Research Center

    1996-12-31

    KECC(Kepco Coal Feeder Control System) receives coal weight, conveyor speed and boiler demand signals. It controls coal flow by generating speed signal of feeder which conveys coal in hopper to pulverizer, displaying measured coal quantity and providing local auto and manual manipulator (author). 33 figs.

  3. Feeder cells support the culture of induced pluripotent stem cells even after chemical fixation.

    Directory of Open Access Journals (Sweden)

    Xiao-Shan Yue

    Full Text Available Chemically fixed mouse embryonic fibroblasts (MEFs, instead of live feeder cells, were applied to the maintenance of mouse induced pluripotent stem (miPS cells. Formaldehyde and glutaraldehyde were used for chemical fixation. The chemically fixed MEF feeders maintained the pluripotency of miPS cells, as well as their undifferentiated state. Furthermore, the chemically fixed MEF feeders were reused several times without affecting their functions. These results indicate that chemical fixation can be applied to modify biological feeders chemically, without losing their original functions. Chemically fixed MEF feeders will be applicable to other stem cell cultures as a reusable extracellular matrix candidate that can be preserved on a long-term basis.

  4. Preliminary analysis of accident in SST-1 current feeder system

    International Nuclear Information System (INIS)

    Roy, Swati; Kanabar, Deven; Garg, Atul; Singh, Amit; Tanna, Vipul; Prasad, Upendra; Srinivasan, R.

    2017-01-01

    Steady-state Tokamak-1 (SST-1) has 16 superconducting Toroidal field (TF) and 9 superconducting poloidal field (PF) coils rated for 10kA DC. All the TF are connected in series and are operated in DC condition whereas PF coils are individually operated in pulse mode during SST-1 campaigns. SST-1 current feeder system (CFS) houses 9 pairs of PF current leads and 1 pair of TF current leads. During past SST-1 campaign, there were arcing incidents within SST-1 CFS chamber which caused significant damage to PF superconducting current leads as well as its Helium cooling lines of the current leads. This paper brings out the preliminary analysis of the mentioned arcing incident, possible reasons and its investigation thereby laying out the sequence of events. From this analysis and observations, various measures to avoid such arcing incidents have also been proposed. (author)

  5. Microplastic in a macro filter feeder: Humpback whale Megaptera novaeangliae.

    Science.gov (United States)

    Besseling, E; Foekema, E M; Van Franeker, J A; Leopold, M F; Kühn, S; Bravo Rebolledo, E L; Heße, E; Mielke, L; IJzer, J; Kamminga, P; Koelmans, A A

    2015-06-15

    Marine filter feeders are exposed to microplastic because of their selection of small particles as food source. Baleen whales feed by filtering small particles from large water volumes. Macroplastic was found in baleen whales before. This study is the first to show the presence of microplastic in intestines of a baleen whale (Megaptera novaeangliae). Contents of its gastrointestinal tract were sieved, dissolved in 10% potassium hydroxide and washed. From the remaining dried material, potential synthetic polymer particles were selected based on density and appearance, and analysed by Fourier transform infrared (FTIR) spectroscopy. Several polymer types (polyethylene, polypropylene, polyvinylchloride, polyethylene terephthalate, nylon) were found, in varying particle shapes: sheets, fragments and threads with a size of 1mm to 17cm. This diversity in polymer types and particle shapes, can be interpreted as a representation of the varying characteristics of marine plastic and the unselective way of ingestion by M. novaeangliae. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Development of an extruder-feeder biomass direct liquefaction process

    Energy Technology Data Exchange (ETDEWEB)

    White, D.H.; Wolf, D. (Arizona Univ., Tucson, AZ (United States). Dept. of Chemical Engineering)

    1991-10-01

    As an abundant, renewable, domestic energy resource, biomass could help the United States reduce its dependence on imported oil. Biomass is the only renewable energy technology capable of addressing the national need for liquid transportation fuels. Thus, there is an incentive to develop economic conversion processes for converting biomass, including wood, into liquid fuels. Through research sponsored by the US DOE's Biomass Thermochemical Conversion Program, the University of Arizona has developed a unique biomass direct liquefaction system. The system features a modified single-screw extruder capable of pumping solid slurries containing as high as 60 wt% wood flour in wood oil derived vacuum bottoms at pressures up to 3000 psi. The extruder-feeder has been integrated with a unique reactor by the University to form a system which offers potential for improving high pressure biomass direct liquefaction technology. The extruder-feeder acts simultaneously as both a feed preheater and a pumping device for injecting wood slurries into a high pressure reactor in the biomass liquefaction process. An experimental facility was constructed and following shakedown operations, wood crude oil was produced by mid-1985. By July 1988, a total of 57 experimental continuous biomass liquefaction runs were made using White Birch wood feedstock. Good operability was achieved at slurry feed rates up to 30 lb/hr, reactor pressures from 800 to 3000 psi and temperatures from 350{degree}C to 430{degree}C under conditions covering a range of carbon monoxide feed rates and sodium carbonate catalyst addition. Crude wood oils containing as little as 6--10 wt% residual oxygen were produced. 38 refs., 82 figs., 26 tabs.

  7. Nitrogen fixed by cyanobacteria is utilized by deposit-feeders.

    Science.gov (United States)

    Karlson, Agnes M L; Gorokhova, Elena; Elmgren, Ragnar

    2014-01-01

    Benthic communities below the photic zone depend for food on allochthonous organic matter derived from seasonal phytoplankton blooms. In the Baltic Sea, the spring diatom bloom is considered the most important input of organic matter, whereas the contribution of the summer bloom dominated by diazotrophic cyanobacteria is less understood. The possible increase in cyanobacteria blooms as a consequence of eutrophication and climate change calls for evaluation of cyanobacteria effects on benthic community functioning and productivity. Here, we examine utilization of cyanobacterial nitrogen by deposit-feeding benthic macrofauna following a cyanobacteria bloom at three stations during two consecutive years and link these changes to isotopic niche and variations in body condition (assayed as C:N ratio) of the animals. Since nitrogen-fixing cyanobacteria have δ(15)N close to -2‰, we expected the δ(15)N in the deposit-feeders to decrease after the bloom if their assimilation of cyanobacteria-derived nitrogen was substantial. We also expected the settled cyanobacteria with their associated microheterotrophic community and relatively high nitrogen content to increase the isotopic niche area, trophic diversity and dietary divergence between individuals (estimated as the nearest neighbour distance) in the benthic fauna after the bloom. The three surface-feeding species (Monoporeia affinis, Macoma balthica and Marenzelleria arctia) showed significantly lower δ(15)N values after the bloom, while the sub-surface feeder Pontoporeia femorata did not. The effect of the bloom on isotopic niche varied greatly between stations; populations which increased niche area after the bloom had better body condition than populations with reduced niche, regardless of species. Thus, cyanobacterial nitrogen is efficiently integrated into the benthic food webs in the Baltic, with likely consequences for their functioning, secondary production, transfer efficiency, trophic interactions, and

  8. Nitrogen fixed by cyanobacteria is utilized by deposit-feeders.

    Directory of Open Access Journals (Sweden)

    Agnes M L Karlson

    Full Text Available Benthic communities below the photic zone depend for food on allochthonous organic matter derived from seasonal phytoplankton blooms. In the Baltic Sea, the spring diatom bloom is considered the most important input of organic matter, whereas the contribution of the summer bloom dominated by diazotrophic cyanobacteria is less understood. The possible increase in cyanobacteria blooms as a consequence of eutrophication and climate change calls for evaluation of cyanobacteria effects on benthic community functioning and productivity. Here, we examine utilization of cyanobacterial nitrogen by deposit-feeding benthic macrofauna following a cyanobacteria bloom at three stations during two consecutive years and link these changes to isotopic niche and variations in body condition (assayed as C:N ratio of the animals. Since nitrogen-fixing cyanobacteria have δ(15N close to -2‰, we expected the δ(15N in the deposit-feeders to decrease after the bloom if their assimilation of cyanobacteria-derived nitrogen was substantial. We also expected the settled cyanobacteria with their associated microheterotrophic community and relatively high nitrogen content to increase the isotopic niche area, trophic diversity and dietary divergence between individuals (estimated as the nearest neighbour distance in the benthic fauna after the bloom. The three surface-feeding species (Monoporeia affinis, Macoma balthica and Marenzelleria arctia showed significantly lower δ(15N values after the bloom, while the sub-surface feeder Pontoporeia femorata did not. The effect of the bloom on isotopic niche varied greatly between stations; populations which increased niche area after the bloom had better body condition than populations with reduced niche, regardless of species. Thus, cyanobacterial nitrogen is efficiently integrated into the benthic food webs in the Baltic, with likely consequences for their functioning, secondary production, transfer efficiency, trophic

  9. Impacting effects of seismic loading in feeder pipes of PHWR power plants

    International Nuclear Information System (INIS)

    Kumar, R.

    1996-01-01

    The core of a pressurized heavy water reactor (PHWR) consists of a large number of fuel channels. These fuel channels are connected to the feeder pipes through which the heavy water flows and transports heat from the reactor core to the steam generators. The feeder pipes are several hundreds in number. They run close to each other with small gaps and have several bends. Thus they represent a complex piping system. Under seismic loading, the adjacent feeder pipes may impact each other. In this paper a simplified procedure has been established to assess such impacting effects. The results of the proposed analysis include bending moment and impact force, which provide the stresses due to impacting effects. These results are plotted in nondimensional form so that they could be utilized for any set of feeder pipes. The procedure used for studying the impacting effects includes seismic analysis of individual feeder pipes without impacting effects, selection of pipes for impact analysis, and estimating their maximum impact velocity. Based on the static and dynamic characteristics of the selected feeder pipes, the maximum bending moment, impact force, and stresses are obtained. The results of this study are useful for quick evaluation of the impacting effects in feeder pipes

  10. Effects of Feeder Cells on Dopaminergic Differentiation of Human Embryonic Stem Cells

    Directory of Open Access Journals (Sweden)

    Zhenqiang Zhao

    2016-12-01

    Full Text Available Mouse embryonic fibroblasts (MEFs and human foreskin fibroblasts (HFFs are used for the culture of human embryonic stem cells (hESCs. MEFs and HFFs differed in their capacity to support the proliferation and pluripotency of hESCs and could affect cardiac differentiation potential of hESCs. The aim of this study was to evaluate the effect of MEFs and HFFs feeders on dopaminergic differentiation of hESCs lines. To minimize the impact of culture condition variation, two hESCs lines were cultured on mixed feeder cells (MFCs, MEFs: HFFs =1:1 and HFFs feeder respectively, and then were differentiated into DA neurons under the identical protocol. Dopaminergic differentiation was evaluated by immunocytochemistry, quantitative fluorescent real-time PCR (qRT-PCR, transmission and scanning electron microscopy, and patch clamp. Our results demonstrated that these hESCs-derived neurons were genuine and functional DA neurons. However, compared to hESCs line on MFCs feeder, hESCs line on HFFs feeder had a higher proportion of TH positive cells and expressed higher levels of FOXA2, PITX3, NURR1 and TH genes. In addition, the values of threshold intensity and threshold membrane potential of DA neurons from hESCs line on HFFs feeder were lower than those of DA neurons from hESCs line on the MFCs feeder. In conclusion, HFFs feeder not only facilitated the differentiation of hESCs cells into dopaminergic neurons, but also induced hESCs-derived DA neurons to express higher electrophysiological excitability. Therefore, feeder cells could affect not only dopaminergic differentiation potential of different hESCs lines, but also electrophysiological properties of hESCs-derived DA neurons.

  11. A novel method for decomposing electricity feeder load into elementary profiles from customer information

    International Nuclear Information System (INIS)

    Gerossier, Alexis; Barbier, Thibaut; Girard, Robin

    2017-01-01

    Highlights: •Use of aggregated electricity load profiles and customer description at feeder level. •Statistical recovery of elementary load profiles with customer categorization. •Generation of load demand profiles for unknown feeders and new local areas. •Relevancy of the different categorizations. -- Abstract: To plan a distribution grid involves making a long-term forecast of sub-hourly demand, which requires modeling the demand and its dynamics with aggregated measurement data. Distribution system operators (DSOs) have been recording electricity sub-hourly demand delivered by their medium-voltage feeders (around 1000—10,000 customers) for several years. Demand profiles differ widely among the various considered feeders. This is partly due to the varying mix of customer categories from one feeder to another. To overcome this issue, elementary demand profiles are often associated with customer categories and then combined according to a mix description. This paper presents a novel method to estimate elementary profiles that only requires several feeder demand curves and a description of customers. The method relies on a statistical blind source model and a new estimation procedure based on the augmented Lagrangian method. The use of feeders to estimate elementary profiles means that measurements are fully representative and continuously updated. We illustrate the proposed method through a case study comprising around 1000 feeder demand curves operated by the main French DSO Enedis. We propose an application o that uses the obtained profiles to evaluate the contribution of any set of new customers to a feeder peak load. We show that profiles enable a simulation of new unmeasured areas with errors of around 20%. We also show how our method can be used to evaluate the relevancy of different customer categorizations.

  12. Improvement of Local Voltage in Feeders with Photovoltaic using Electric Vehicles

    DEFF Research Database (Denmark)

    Marra, Francesco; Yang, Guangya; Fawzy, Y. T.

    2013-01-01

    In low-voltage (LV) feeders with high penetration of photovoltaic (PV), a major issue to be solved is voltage rise due to the active power injection. If no measures are taken, this may lead to generation’s interruptions and to the malfunctioning of domestic appliances due to non-standard voltage...... profiles. This paper proposes a storage strategy to alleviate voltage rise in feeders with PV, using coordinated electric vehicle (EV) load as the storage solution. The voltage support strategy is easy to implement practically and it is demonstrated on a test feeder emulating a household with roof...

  13. A Review of Power Distribution Test Feeders in the United States and the Need for Synthetic Representative Networks

    Directory of Open Access Journals (Sweden)

    Fernando E. Postigo Marcos

    2017-11-01

    Full Text Available Under the increasing penetration of distributed energy resources and new smart network technologies, distribution utilities face new challenges and opportunities to ensure reliable operations, manage service quality, and reduce operational and investment costs. Simultaneously, the research community is developing algorithms for advanced controls and distribution automation that can help to address some of these challenges. However, there is a shortage of realistic test systems that are publically available for development, testing, and evaluation of such new algorithms. Concerns around revealing critical infrastructure details and customer privacy have severely limited the number of actual networks published and that are available for testing. In recent decades, several distribution test feeders and US-featured representative networks have been published, but the scale, complexity, and control data vary widely. This paper presents a first-of-a-kind structured literature review of published distribution test networks with a special emphasis on classifying their main characteristics and identifying the types of studies for which they have been used. This both aids researchers in choosing suitable test networks for their needs and highlights the opportunities and directions for further test system development. In particular, we highlight the need for building large-scale synthetic networks to overcome the identified drawbacks of current distribution test feeders.

  14. Minimal incorporation of Deepwater Horizon oil by estuarine filter feeders

    International Nuclear Information System (INIS)

    Fry, Brian; Anderson, Laurie C.

    2014-01-01

    Highlights: • Oil from the Deepwater Horizon oil spill entered Louisiana bays in mid-2010. • Oil was used minimally (<1%) in diets of mussels and barnacles. • Also, oil did not enhance planktonic respiration rates. • Use of oil carbon was relatively small in these productive estuarine food webs. - Abstract: Natural abundance carbon isotope analyses are sensitive tracers for fates and use of oil in aquatic environments. Use of oil carbon in estuarine food webs should lead to isotope values approaching those of oil itself, −27‰ for stable carbon isotopes reflecting oil origins and −1000‰ for carbon-14 reflecting oil age. To test for transfer of oil from the 2010 Deepwater Horizon spill into estuarine food webs, filter-feeding barnacles (Balanus sp.) and marsh mussels (Geukensia demissa) were collected from Louisiana estuaries near the site of the oil spill. Carbon-14 analyses of these animals from open waters and oiled marshes showed that oil use was <1% and near detection limits estimated at 0.3% oil incorporation. Respiration studies showed no evidence for enhanced microbial activity in bay waters. Results are consistent with low dietary impacts of oil for filter feeders and little overall impact on respiration in the productive Louisiana estuarine systems

  15. Automatic feeder for small fish held in tanks

    Science.gov (United States)

    Joeris, Leonard S.

    1965-01-01

    The Northville (Michigan) Biological Station has been a center for study of the developmental morphology of coregonid fishes. This work requires the production of numerous individual series of lake herring, lake whitefish, and several species of chubs from parent fish of positively known identity. The offspring of individual pairs or groups of fish must be held in individual tanks from the time they hatch until they reach maturity. One of the important problems in this project has been the poor growth of most fish. Though some have grown well, their growth has been less than that of the same species in nature, and a few fish from each hatch have grown very slowly. Irregularity of feeding may contribute to the slow growth of laboratory fish. The hatchery caretaker feeds them several times during his 8-hour workday, but they must go without food during the remaining 16 hours. The high metabolic rate of small fish, however, appears to make them strongly inclined toward almost continual feeding. Belief that greater, more regular food consumption would result from a mechanical feeder providing a continuous supply of food over a longer period of the day led to development of the equipment described in this paper.

  16. Decision Support for Optimal Repositioning of Containers in a Feeder System

    Directory of Open Access Journals (Sweden)

    Danijela Tuljak-Suban

    2008-03-01

    Full Text Available The transport of empty containers represents a seriousproblem in the fast growing sphere of maritime container transport.The most widespread type of container transport organizationin maritime transport is the hub and spoke mode, whichenables the transport of a great number of containers via largevessels between hub ports, from where feeder ships transport tosmaller ports that thus gravitate to the central hub port. The articlecontains a detailed analysis of the northern Adriatic portsand the feeder connections with the hub ports of the Mediterranean.A two-level VRPPD (Vehicle Routing Problem withPickup and Delivery problem is modelled on a graph, wherethe transport of full containers is privileged over the transport ofempty containers. This enables the simulation of the feeder systemin the n01them Adriatic, meaning that it shows the ship'soperator the movement programme with minimal transportcosts for the superfluous empty containers in the complex of theregular transports of full containers in the feeder system.

  17. Manufacture and test of seismic bellows for ITER magnet feeder

    International Nuclear Information System (INIS)

    Liu, Chen; Lu, Kun; Sheng, Liang; Song, Yuntao; Su, Jinjin; Su, Man; Gung, Chenyu

    2016-01-01

    Highlights: • The design of the double bellows was iterated with the results of analysis based on the Expansion Joint Manufacturers Association (EJMA) standard. • The seismic bellows was tested with cyclic pressurization of the interlayer space to 2 bars absolute pressure for 5 cycles. • 200 cycles of tensile fatigue test with 90 mm of stretching from the nominal design length. • A full tensile test with 315 mm of stretching from its nominal length was conducted. • The prototype bellows was qualified for its leak tightness (less than 1 × 10 −9 Pam 3 /s of helium) at all time during the qualification test. - Abstract: This paper presents the key manufacturing and testing processes of the prototype ITER feeder seismic bellows. The design of the double bellows was iterated with the results of analysis based on the Expansion Joint Manufacturers Association (EJMA) standard. Each inner and outer bellows was supported in dedicated molds and formed by a hydraulic pressure machine rated at 800 tons. The double bellows were constructed by welding individual collars to the end flanges. The seismic bellows was tested with cyclic pressurization of the interlayer space to 2 bars absolute pressure for 5 cycles. This was followed by 200 cycles of tensile fatigue test with 90 mm of stretching from the nominal design length. After the mechanical fatigue test, a full tensile test with 315 mm of stretching from its nominal length was conducted. Helium leak tests, with the sensitivity of the helium leak detector set to 1 × 10 −9 Pa m 3 /s of helium, were performed at different stages of pressure and mechanical tests. The prototype bellows was qualified for its leak tightness at all time during the qualification test.

  18. Manufacture and test of seismic bellows for ITER magnet feeder

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Chen, E-mail: liuchen@ipp.ac.cn [Institute of Plasma Physics Chinese Academy of Sciences, ShuShanhu Road No. 350, Hefei (China); Lu, Kun [Institute of Plasma Physics Chinese Academy of Sciences, ShuShanhu Road No. 350, Hefei (China); Sheng, Liang [AEROSUN-TOLA Expansion Joint Co., Ltd., Jiangjun Road No. 199, Nanjing (China); Song, Yuntao; Su, Jinjin [Institute of Plasma Physics Chinese Academy of Sciences, ShuShanhu Road No. 350, Hefei (China); Su, Man; Gung, Chenyu [ITER Organization, Route de Vinon-sur-Verdon, CS 90 046, 13067 St. Paul-lez-Durance (France)

    2016-11-01

    Highlights: • The design of the double bellows was iterated with the results of analysis based on the Expansion Joint Manufacturers Association (EJMA) standard. • The seismic bellows was tested with cyclic pressurization of the interlayer space to 2 bars absolute pressure for 5 cycles. • 200 cycles of tensile fatigue test with 90 mm of stretching from the nominal design length. • A full tensile test with 315 mm of stretching from its nominal length was conducted. • The prototype bellows was qualified for its leak tightness (less than 1 × 10{sup −9} Pam{sup 3}/s of helium) at all time during the qualification test. - Abstract: This paper presents the key manufacturing and testing processes of the prototype ITER feeder seismic bellows. The design of the double bellows was iterated with the results of analysis based on the Expansion Joint Manufacturers Association (EJMA) standard. Each inner and outer bellows was supported in dedicated molds and formed by a hydraulic pressure machine rated at 800 tons. The double bellows were constructed by welding individual collars to the end flanges. The seismic bellows was tested with cyclic pressurization of the interlayer space to 2 bars absolute pressure for 5 cycles. This was followed by 200 cycles of tensile fatigue test with 90 mm of stretching from the nominal design length. After the mechanical fatigue test, a full tensile test with 315 mm of stretching from its nominal length was conducted. Helium leak tests, with the sensitivity of the helium leak detector set to 1 × 10{sup −9} Pa m{sup 3}/s of helium, were performed at different stages of pressure and mechanical tests. The prototype bellows was qualified for its leak tightness at all time during the qualification test.

  19. Changes in thunderstorm characteristics due to feeder cloud merging

    Science.gov (United States)

    Sinkevich, Andrei A.; Krauss, Terrence W.

    2014-06-01

    Cumulus cloud merging is a complex dynamical and microphysical process in which two convective cells merge into a single cell. Previous radar observations and numerical simulations have shown a substantial increase in the maximum area, maximum echo top and maximum reflectivity as a result of the merging process. Although the qualitative aspects of merging have been well documented, the quantitative effects on storm properties remain less defined. Therefore, a statistical assessment of changes in storm characteristics due to merging is of importance. Further investigation into the effects of cloud merging on precipitation flux (Pflux) in a statistical manner provided the motivation for this study in the Asir region of Saudi Arabia. It was confirmed that merging has a strong effect on storm development in this region. The data analysis shows that an increase in the median of the distribution of maximum reflectivity was observed just after merging and was equal to 3.9 dBZ. A detailed analysis of the individual merge cases compared the merged storm Pflux and mass to the sum of the individual Feeder and Storm portions just before merging for each case. The merged storm Pflux increased an average of 106% over the 20-min period after merging, and the mass increased on average 143%. The merged storm clearly became larger and more severe than the sum of the two parts prior to merging. One consequence of this study is that any attempts to evaluate the precipitation enhancement effects of cloud seeding must also include the issue of cloud mergers because merging can have a significant effect on the results.

  20. Cost Benefit and Alternatives Analysis of Distribution Systems with Energy Storage Systems: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Harris, Tom; Nagarajan, Adarsh; Baggu, Murali; Bialek, Tom

    2017-06-27

    This paper explores monetized and non-monetized benefits from storage interconnected to distribution system through use cases illustrating potential applications for energy storage in California's electric utility system. This work supports SDG&E in its efforts to quantify, summarize, and compare the cost and benefit streams related to implementation and operation of energy storage on its distribution feeders. This effort develops the cost benefit and alternatives analysis platform, integrated with QSTS feeder simulation capability, and analyzed use cases to explore the cost-benefit of implementation and operation of energy storage for feeder support and market participation.

  1. Development of a feeder device for logging residue for a drum chipper; Hakkurin syoetoen kehittaeminen energiapuulle

    Energy Technology Data Exchange (ETDEWEB)

    Leinonen, T.; Kemppainen, J P [Oulu Univ. (Finland). Dept. of Mechanical Engineering

    1997-12-01

    The aim of this project is to increase the productivity of a large drum chipper by developing a feeder device to be used especially when chipping logging residue. Logging residue from regeneration areas is the most important reserve of forest biomass for the production of renewable energy in Finland. It is possible ecologically and economically to use about 5 million m{sup 3} of logging residue yearly for energy purposes. Currently both large lorry based chippers and smaller forwarder based chippers are used for chipping logging residue. However even the latest versions of these chippers are not well equipped for chipping logging residue. The ball like shape of residue piles causes blockades, if too large amounts of residue are fed into the chipper. Keeping the material flow even is difficult. In this project a prototype of a feeder device will be designed and manufactured to exactly find out the problems, that occur when feeding logging residue to a chipper. The designed prototype is based on a tubular chassis, which supports a conveyor made of steel plates. Prototype also has a 2,5 m wide feeding table and a feeder roll, which is located above the conveyor just before the chipper opening. Both the conveyor and the feeder roll are powered by hydraulic motors. The maximum feeding force is 20 kN. For research purposes both hydraulic pressure and flow can be adjusted individually for both motors. During 1996 activities included designing and building the prototype feeder device. In 1997 the prototype will be tested to find out possible problems, which need to be cured. After problems are solved and other improvements are made, the feeder device will be installed to an existing chipper and then tested again to determine the productivity of the new feeder device compared to the old unit. (orig.)

  2. Expression and secretory profile of buffalo fetal fibroblasts and Wharton's jelly feeder layers.

    Science.gov (United States)

    Parmar, Mehtab S; Mishra, Smruti Ranjan; Somal, Anjali; Pandey, Sriti; Kumar, G Sai; Sarkar, Mihir; Chandra, Vikash; Sharma, G Taru

    2017-05-01

    The present study examined the comparative expression and secretory profile of vital signaling molecules in buffalo fetal fibroblasts (BFF) and Wharton's jelly (BWJ) feeder layers at different passages. Both feeder layers were expanded up to 8th passage. Signaling molecules viz. bone morphogenetic protein 4 (BMP4), fibroblast growth factor 2 (FGF2), leukemia inhibitory factor (LIF) and transforming growth factor beta 1 (TGFB1) and pluripotency-associated transcriptional factors (POU5F1, SOX2, NANOG, KLF4, MYC and FOXD3) were immunolocalized in the both feeder types. A clear variation in the expression pattern of key signaling molecules with passaging was registered in both feeders compared to primary culture (0 passage). The conditioned media (CM) was collected from different passages (2, 4, 6, 8) of both the feeder layers and was quantified using enzyme-linked immunosorbent assay (ELISA). Concomitant to expression profile, protein quantification also revealed differences in the concentration of signaling molecules at different time points. Conjointly, expression and secretory profile revealed that 2nd passage of BFF and 6th passage of BWJ exhibit optimal levels of key signaling molecules thus may be selected as best passages for embryonic stem cells (ESCs) propagation. Further, the effect of mitomycin-C (MMC) treatment on the expression profile of signaling molecules in the selected passages of BFF and BWJ revealed that MMC modulates the expression profile of these molecules. In conclusion, the results indicate that feeder layers vary in expression and secretory pattern of vital signaling molecules with passaging. Based on these findings, the appropriate feeder passages may be selected for the quality propagation of buffalo ESCs. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Network Reduction Algorithm for Developing Distribution Feeders for Real-Time Simulators: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Nagarajan, Adarsh; Nelson, Austin; Prabakar, Kumaraguru; Hoke, Andy; Asano, Marc; Ueda, Reid; Nepal, Shaili

    2017-06-15

    As advanced grid-support functions (AGF) become more widely used in grid-connected photovoltaic (PV) inverters, utilities are increasingly interested in their impacts when implemented in the field. These effects can be understood by modeling feeders in real-time systems and testing PV inverters using power hardware-in-the-loop (PHIL) techniques. This paper presents a novel feeder model reduction algorithm using a Monte Carlo method that enables large feeders to be solved and operated on real-time computing platforms. Two Hawaiian Electric feeder models in Synergi Electric's load flow software were converted to reduced order models in OpenDSS, and subsequently implemented in the OPAL-RT real-time digital testing platform. Smart PV inverters were added to the real-time model with AGF responses modeled after characterizing commercially available hardware inverters. Finally, hardware inverters were tested in conjunction with the real-time model using PHIL techniques so that the effects of AGFs on the choice feeders could be analyzed.

  4. Comparing the engineering program feeders from SiF and convention models

    Science.gov (United States)

    Roongruangsri, Warawaran; Moonpa, Niwat; Vuthijumnonk, Janyawat; Sangsuwan, Kampanart

    2018-01-01

    This research aims to compare the relationship between two types of engineering program feeder models within the technical education systems of Rajamangala University of Technology Lanna (RMUTL), Chiangmai, Thailand. To illustrate, the paper refers to two typologies of feeder models, which are the convention and the school in factory (SiF) models. The new SiF model is developed through a collaborative educational process between the sectors of industry, government and academia, using work-integrated learning. The research methodology were use to compared features of the the SiF model with conventional models in terms of learning outcome, funding budget for the study, the advantages and disadvantages from the point of view of students, professors, the university, government and industrial partners. The results of this research indicate that the developed SiF feeder model is the most pertinent ones as it meet the requirements of the university, the government and the industry. The SiF feeder model showed the ability to yield positive learning outcomes with low expenditures per student for both the family and the university. In parallel, the sharing of knowledge between university and industry became increasingly important in the process, which resulted in the improvement of industrial skills for professors and an increase in industrial based research for the university. The SiF feeder model meets its demand of public policy in supporting a skilled workforce for the industry, which could be an effective tool for the triple helix educational model of Thailand.

  5. EV Charging Facilities and Their Application in LV Feeders with Photovoltaics

    DEFF Research Database (Denmark)

    Marra, Francesco; Yang, Guangya; Træholt, Chresten

    2013-01-01

    Low-voltage (LV) grid feeders with high penetration of photovoltaics (PVs) are often affected by voltage magnitude problems. To solve such issues, previous research has shown that reactive power methods, active power curtailment and grid reinforcement can be used for voltage support, yet showing...... several limits. We introduce the use of electric vehicle (EV) public charging stations with energy storage system (ESS) as a solution for voltage regulation in LV feeders with PV. A novel method is proposed to determine the ESS charging load required for voltage regulation and compare the results...... for the different locations in the feeder. With time-series simulations, we quantify the energy size required for a station ESS. A Belgian LV residential grid, modeled using real PV generation and load profiles, is used as case study. The method and simulation results show the effectiveness of using public EV...

  6. Convex relaxation of Optimal Power Flow in Distribution Feeders with embedded solar power

    DEFF Research Database (Denmark)

    Hermann, Alexander Niels August; Wu, Qiuwei; Huang, Shaojun

    2016-01-01

    There is an increasing interest in using Distributed Energy Resources (DER) directly coupled to end user distribution feeders. This poses an array of challenges because most of today’s distribution feeders are designed for unidirectional power flow. Therefore when installing DERs such as solar...... panels with uncontrolled inverters, the upper limit of installable capacity is quickly reached in many of today’s distribution feeders. This problem can often be mitigated by optimally controlling the voltage angles of inverters. However, the optimal power flow problem in its standard form is a large...... scale non-convex optimization problem, and thus can’t be solved precisely and also is computationally heavy and intractable for large systems. This paper examines the use of a convex relaxation using Semi-definite programming to optimally control solar power inverters in a distribution grid in order...

  7. A probabilistic degradation model for the estimation of the remaining life distribution of feeders

    International Nuclear Information System (INIS)

    Yuan, X.-X.; Pandey, M.D.; Bickel, G.A.

    2006-01-01

    Wall thinning due to flow accelerated corrosion (FAC) is a pervasive form of degradation in the outlet feeder pipes of the primary heat transport system of CANDU reactors. The prediction of the end-of-life of a feeder from wall thickness measurement data is confounded by the sampling and temporal uncertainties associated with the FAC degradation phenomenon. Traditional regression-based statistical methods deal with only the sampling uncertainties, leaving the temporal uncertainties unresolved. This paper presents an advanced probabilistic model, which is able to integrate the temporal uncertainties into the prediction of lifetime. In particular, a random gamma process model is proposed to model the FAC process and it is calibrated with a set of wall thickness measurements using the method of maximum likelihood. This information can be used to establish an optimum strategy for inspection and replacement of feeders. (author)

  8. OPTIMIZATION OF LONG RURAL FEEDERS USING A GENETIC ALGORITHM

    International Nuclear Information System (INIS)

    Wishart, Michael; Ledwich, Gerard; Ghosh, Arindam; Ivanovich, Grujica

    2010-01-01

    This paper describes the optimization of conductor size and the voltage regulator location and magnitude of long rural distribution lines. The optimization minimizes the lifetime cost of the lines, including capital costs and losses while observing voltage drop and operational constraints using a Genetic Algorithm (GA). The GA optimization is applied to a real Single Wire Earth Return (SWER) network in regional Queensland and results are presented.

  9. Impact of Distribution Feeders that do not have Voltage Regulators on the number of Charged Electric Vehicles using IEEE 34 Bus Test Feeder

    Energy Technology Data Exchange (ETDEWEB)

    Allehyani, Ahmed [University of Southern California, Department of Electrical Engineering; Beshir, Mohammed [University of Southern California, Department of Electrical Engineering

    2015-02-01

    Voltage regulators help maintain an acceptable voltage profile for the system. This paper discusses the effect of installing voltage regulators to the system to fix the voltage drop resulting from the electrical vehicles loading increase when they are being charged. The effect will be studied in the afternoon, when the peak load occurs, using the IEEE 34 bus test feeder. First, only one spot node is used to charge the electric vehicles while a voltage regulator is present. Second, five spot nodes are loaded at the same time to charge the electric vehicles while voltage regulators are installed at each node. After that, the impact of electric vehicles on distribution feeders that do not have voltage regulators will appear.

  10. Effect of artificial feeders on pollen loads of the hummingbirds of Cerro de La Muerte, Costa Rica

    Directory of Open Access Journals (Sweden)

    Gerardo Avalos

    2012-03-01

    Full Text Available Although sugar-water feeders are commonly used by enthusiasts to attract hummingbirds, little is known about how they affect hummingbird behavior and flower use. We studied the highland hummingbird assemblage of Cerro de La Muerte, Costa Rica, both at a site with permanent feeders (La Georgina Restaurant and further from it. We examined how feeder use and monopolization affected seasonal changes in pollen loads during four sampling periods, including dry and wet seasons, from 2003-2005. We expected that species monopolizing the feeders would carry little or no pollen whatsoever, and would have pollen loads characterized by low floral diversity, in contrast with species less dependent on feeders. We obtained pollen samples from 183 individuals of four hummingbird species captured around the feeders using mist nets, which were compared with a pollen reference collection of plants with a pollination syndrome by hummingbirds. The same methods were implemented at a site 3km away from the feeders. Feeder usage was quantified by counting the number of times hummingbirds drank from the feeders in periods of 4min separated by 1min. The effects of hummingbird species and season on pollen load categories were assessed using a nominal logistic regression. The alpha species at the site, the Fiery-throated Hummingbird (Panterpe insignis, dominated the feeders during the dry season. Meanwhile, in the wet season, feeder usage was more evenly distributed across species, with the exception of the Volcano Hummingbird, Selasphorus flammula, which occupies the last place in the dominance hierarchy. Pollen loads of hummingbirds captured near feeders were low in abundance (more than 50% of captured individuals had zero or low pollen loads, and low in species richness (96% of the hummingbirds with pollen from only one plant genus, Centropogon. Overall pollen loads increased during the dry season coinciding with peaks in flower availability, although the majority of

  11. Effect of artificial feeders on pollen loads of the hummingbirds of Cerro de la Muerte, Costa Rica.

    Science.gov (United States)

    Avalos, Gerardo; Soto, Alejandra; Alfaro, Willy

    2012-03-01

    Although sugar-water feeders are commonly used by enthusiasts to attract hummingbirds, little is known about how they affect hummingbird behavior and flower use. We studied the highland hummingbird assemblage of Cerro de La Muerte, Costa Rica, both at a site with permanent feeders (La Georgina Restaurant) and further from it. We examined how feeder use and monopolization affected seasonal changes in pollen loads during four sampling periods, including dry and wet seasons, from 2003-2005. We expected that species monopolizing the feeders would carry little or no pollen whatsoever, and would have pollen loads characterized by low floral diversity, in contrast with species less dependent on feeders. We obtained pollen samples from 183 individuals of four hummingbird species captured around the feeders using mist nets, which were compared with a pollen reference collection of plants with a pollination syndrome by hummingbirds. The same methods were implemented at a site 3km away from the feeders. Feeder usage was quantified by counting the number of times hummingbirds drank from the feeders in periods of 4min separated by 1min. The effects of hummingbird species and season on pollen load categories were assessed using a nominal logistic regression. The alpha species at the site, the Fiery-throated Hummingbird (Panterpe insignis), dominated the feeders during the dry season. Meanwhile, in the wet season, feeder usage was more evenly distributed across species, with the exception of the Volcano Hummingbird, Selasphorus flammula, which occupies the last place in the dominance hierarchy. Pollen loads of hummingbirds captured near feeders were low in abundance (more than 50% of captured individuals had zero or low pollen loads), and low in species richness (96% of the hummingbirds with pollen from only one plant genus, Centropogon). Overall pollen loads increased during the dry season coinciding with peaks in flower availability, although the majority of captured

  12. A feeder protection method against the phase-phase fault using symmetrical components

    DEFF Research Database (Denmark)

    Ciontea, Catalin-Iosif; Bak, Claus Leth; Blaabjerg, Frede

    2017-01-01

    generation and relatively reduced short-circuit currents, thus resembling the electric network on a ship. The simulation results demonstrate that the proposed method of protection provides an improved performance compared to the conventional OverCurrent relays in a radial feeder with variable short......The method of symmetrical components simplifies analysis of an electric circuit during the fault and represents an important tool for the protection engineers. In this paper, the symmetrical components of the fault current are used in a new feeder protection method for the maritime applications...

  13. The impact of small benthic passive suspension feeders in shallow marine ecosystems: the hydroids as an example

    NARCIS (Netherlands)

    Gili, J.-M.; Alvà, V.; Coma, R.; Orejas, C.; Pagès, F.; Ribes, M.; Zabala, M.; Arntz, W.; Bouillon, J.; Boero, F.; Hughes, R.G.

    1998-01-01

    Benthic suspension feeders are abundant in littoral and shallow sub-littoral ecosystems, where they feed on the plankton and on organic matter suspended in the water column. Recent studies indicate that active suspension feeders with powerful water filtration mechanisms (e.g., bivalve molluscs) may

  14. Optimalisatie performance van vleeskuikens bij mobiel voer- en drinksysteem (scanFeeder) op praktijkbedrijf

    NARCIS (Netherlands)

    Harn, van J.; Veldkamp, T.

    2007-01-01

    Het gebruik van de Ridder ScanFeeder, een mobiel voer- en drinksysteem met strooiselbeluchting voor vleeskuikens, geeft een betere strooiselkwaliteit (ruller en droger strooisel) en minder voetzoolaandoeningen. De technische resultaten bij dit systeem blijven echter achter bij die van een

  15. Hybrid RSOA and fibre raman amplified long reach feeder link for WiMAX-on-fibre

    DEFF Research Database (Denmark)

    Amaya Fernández, Ferney Orlando; Martinez, Javier; Yu, Xianbin

    2009-01-01

    A distributed fibre Raman amplified long reach optical access feeder link using a reflective semiconductor optical amplifier in the remote base station is experimentally demonstrated for supporting WiMAXover- fibre transmission. The measured values for the error vector magnitude for quadrature...

  16. Tits recognize the potential dangers of predators and harmless birds in feeder experiments

    Czech Academy of Sciences Publication Activity Database

    Tvardíková, Kateřina; Fuchs, R.

    2012-01-01

    Roč. 30, č. 1 (2012), s. 157-165 ISSN 0289-0771 Grant - others:AV ČR(CZ) IAA601410803 Institutional research plan: CEZ:AV0Z50070508 Keywords : feeders * predator recognition * risk Subject RIV: EH - Ecology, Behaviour Impact factor: 1.000, year: 2012 http://www.springerlink.com/content/2338033t30261604/fulltext.pdf

  17. Evolution of generic supporting conditions for feeders of 500 M We PHWR

    International Nuclear Information System (INIS)

    Prasad, K.H.; Gupta, K.N.; Bapat, C.N.; Sharma, V.K.; Mishra, R.; Soni, R.S.; Kushwaha, H.S.; Mahajan, S.C.; Kakodkar, A.

    1995-01-01

    Feeder piping consists of 784 number of closely spaced, inter-connected flexible pipes catering for large thermal and creep movements besides seismic and other loadings. The analytical strategy for evolving generic supporting conditions is outlined in this paper. (author). 4 refs., 7 figs

  18. Effects of an increasing filter feeder stock on larval abundance in the Oosterschelde estuary (SW Netherlands)

    NARCIS (Netherlands)

    Troost, Karin; Gelderman, Edzard; Kamermans, Pauline; Smaal, Aad C.; Wolff, Wim J.

    Predation by adult bivalves oil bivalve larvae has been suggested to reduce larval abundance in areas with high bivalve filter-feeder biomass. Although the occurrence of larviphagy is well-studied in the laboratory, its effects in the field have scarcely been studied. We studied larviphagy at

  19. Effects of an increasing filter feeder stock on larval abundance in the Oosterschelde estuary (SW Netherlands)

    NARCIS (Netherlands)

    Troost, K.; Gelderman, E.A.C.; Kamermans, P.; Smaal, A.C.; Wolff, W.

    2009-01-01

    Predation by adult bivalves on bivalve larvae has been suggested to reduce larval abundance in areas with high bivalve filter-feeder biomass. Although the occurrence of larviphagy is well-studied in the laboratory, its effects in the field have scarcely been studied. We studied larviphagy at

  20. Interactions among contaminant exposure route, kinetics and toxicity in marine deposit-feeders

    DEFF Research Database (Denmark)

    Selck, Henriette

    Many of the chemicals having the greatest likelihood of causing damage in ecological systems, such as polycyclic aromatic hydrocarbons (PAHs) and metals are of persistent and/or hydrophobic character. Deposit-feeders may be important in facilitating the removal of organic contaminants from bulk...

  1. Feeder Cell Type Affects the Growth of In Vitro Cultured Bovine Trophoblast Cells

    Directory of Open Access Journals (Sweden)

    Islam M. Saadeldin

    2017-01-01

    Full Text Available Trophectoderm cells are the foremost embryonic cells to differentiate with prospective stem-cell properties. In the current study, we aimed at improving the current approach for trophoblast culture by using granulosa cells as feeders. Porcine granulosa cells (PGCs compared to the conventional mouse embryonic fibroblasts (MEFs were used to grow trophectoderm cells from hatched bovine blastocysts. Isolated trophectoderm cells were monitored and displayed characteristic epithelial/cuboidal morphology. The isolated trophectoderm cells expressed mRNA of homeobox protein (CDX2, cytokeratin-8 (KRT8, and interferon tau (IFNT. The expression level was higher on PGCs compared to MEFs throughout the study. In addition, primary trophectoderm cell colonies grew faster on PGCs, with a doubling time of approximately 48 hrs, compared to MEFs. PGCs feeders produced a fair amount of 17β-estradiol and progesterone. We speculated that the supplementation of sex steroids and still-unknown factors during the trophoblasts coculture on PGCs have helped to have better trophectoderm cell’s growth than on MEFs. This is the first time to use PGCs as feeders to culture trophectoderm cells and it proved superior to MEFs. We propose PGCs as alternative feeders for long-term culture of bovine trophectoderm cells. This model will potentially benefit studies on the early trophoblast and embryonic development in bovines.

  2. The effect of stocking density and bin feeder space on performance ...

    African Journals Online (AJOL)

    Unknown

    The effect of stocking density and bin feeder space on performance in pigs. G.A. Lavers# and N.S. Ferguson. School of Agricultural Sciences & Agribusiness, University of Natal, P Bag X01, Scottsville 3209. #Email: lavers@agric.unp.ac.za. Introduction. Pigs housed individually have been shown to have higher feed intakes ...

  3. The effect of stocking density and bin feeder space on performance ...

    African Journals Online (AJOL)

    The effect of stocking density and bin feeder space on performance in pigs. G.A. Lavers, N.S. Ferguson. Abstract. (South African J of Animal Science, 2000, 30, Supplement 1: 70-71). Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

  4. Tumor Volume Decrease via Feeder Occlusion for Treating a Large, Firm Trigone Meningioma.

    Science.gov (United States)

    Nakashima, Takuma; Hatano, Norikazu; Kanamori, Fumiaki; Muraoka, Shinsuke; Kawabata, Teppei; Takasu, Syuntaro; Watanabe, Tadashi; Kojima, Takao; Nagatani, Tetsuya; Seki, Yukio

    2018-01-01

    Trigone meningiomas are considered a surgical challenge, as they tend to be considerably large and hypervascularized at the time of presentation. We experienced a case of a large and very hard trigone meningioma that was effectively treated using initial microsurgical feeder occlusion followed by surgery in stages. A 19-year-old woman who presented with loss of consciousness was referred to our hospital for surgical treatment of a brain tumor. Radiological findings were compatible with a left ventricular trigone meningioma extending laterally in proximity to the Sylvian fissure. At initial surgery using the transsylvian approach, main feeders originating from the anterior and lateral posterior choroidal arteries were occluded at the inferior horn; however, only a small section of the tumor could initially be removed because of its firmness. Over time, feeder occlusion resulted in tumor necrosis and a 20% decrease in its diameter; the mass effect was alleviated within 1 year. The residual meningioma was then totally excised in staged surgical procedures after resection became more feasible owing to ischemia-induced partial softening of the tumor. When a trigone meningioma is large and very hard, initial microsurgical feeder occlusion in the inferior horn can be a safe and effective option, and can lead to necrosis, volume decrease, and partial softening of the residual tumor to allow for its staged surgical excision.

  5. Operation of a cell feeder for coal controlled by a frequency converter. [Czechoslovakia

    Energy Technology Data Exchange (ETDEWEB)

    Stonawski, J; Sikora, G

    1984-02-01

    Steam boiler of the Trinec coal-fired power plant with a capacity of 125 t/h, 545 C, 9.5 MPa was equipped with a screw coal feeder with the KT26A-6 Winter-Eichberg motor with a transformer. The screw fee

  6. Co-ordination of directional overcurrent protection with load current for parallel feeders

    Energy Technology Data Exchange (ETDEWEB)

    Wright, J.W.; Lloyd, G.; Hindle, P.J. [Alstom, Inc., Stafford (United Kingdom). T and D Protection and Control

    1999-11-01

    Directional phase overcurrent relays are commonly applied at the receiving ends of parallel feeders or transformer feeders. Their purpose is to ensure full discrimination of main or back-up power system overcurrent protection for a fault near the receiving end of one feeder. This paper reviews this type of relay application and highlights load current setting constraints for directional protection. Such constraints have not previously been publicized in well-known text books. A directional relay current setting constraint that is suggested in some text books is based purely on thermal rating considerations for older technology relays. This constraint may not exist with modern numerical relays. In the absence of any apparent constraint, there is a temptation to adopt lower current settings with modern directional relays in relation to reverse load current at the receiving ends of parallel feeders. This paper identifies the danger of adopting very low current settings without any special relay feature to ensure protection security with load current during power system faults. A system incident recorded by numerical relays is also offered to highlight this danger. In cases where there is a need to infringe the identified constraints an implemented and testing relaying technique is proposed.

  7. A Branch-and-Price Approach to the Feeder Network Design Problem

    DEFF Research Database (Denmark)

    Santini, Alberto; Plum, Christian Edinger Munk; Røpke, Stefan

    2017-01-01

    In this paper we consider the problem of designing a container liner shipping feeder network. The designer has to choose which port to serve during many rotations that start and end at a central hub. Many operational characteristics are considered, such as variable leg-by-leg speeds and cargo...

  8. harmonic load modeling: a case study of 33 kv abuja steel mill feeder

    African Journals Online (AJOL)

    HOD

    An in-depth study of the harmonic orders inherent in a power system network is required ... This paper studied the harmonic orders of the 33 kV Abuja Steel Feeder .... models for various industrial and household electrical ..... Malaysia, 2013.

  9. Effects of different feeder layers on culture of bovine embryonic stem cell-like cells in vitro.

    Science.gov (United States)

    Cong, Shan; Cao, Guifang; Liu, Dongjun

    2014-12-01

    To find a suitable feeder layer is important for successful culture conditions of bovine embryonic stem cell-like cells. In this study, expression of pluripotency-related genes OCT4, SOX2 and NANOG in bovine embryonic stem cell-like cells on mouse embryonic fibroblast feeder layers at 1-5 passages were monitored in order to identify the possible reason that bovine embryonic stem cell-like cells could not continue growth and passage. Here, we developed two novel feeder layers, mixed embryonic fibroblast feeder layers of mouse and bovine embryonic fibroblast at different ratios and sources including mouse fibroblast cell lines. The bovine embryonic stem cell-like cells generated in our study displayed typical stem cell morphology and expressed specific markers such as OCT4, stage-specific embryonic antigen 1 and 4, alkaline phosphatase, SOX2, and NANOG mRNA levels. When feeder layers and cell growth factors were removed, the bovine embryonic stem cell-like cells formed embryoid bodies in a suspension culture. Furthermore, we compared the expression of the pluripotent markers during bovine embryonic stem cell-like cell in culture on mixed embryonic fibroblast feeder layers, including mouse fibroblast cell lines feeder layers and mouse embryonic fibroblast feeder layers by real-time quantitative polymerase chain reaction. Results suggested that mixed embryonic fibroblast and sources including mouse fibroblast cell lines feeder layers were more suitable for long-term culture and growth of bovine embryonic stem cell-like cells than mouse embryonic fibroblast feeder layers. The findings may provide useful experimental data for the establishment of an appropriate culture system for bovine embryonic stem cell lines.

  10. Impact of feeder space on laying hen feeding behavior and production performance in enriched colony housing.

    Science.gov (United States)

    Oliveira, J L; Xin, H; Wu, H

    2018-05-30

    Current feeder space recommendations in laying hen welfare guidelines are inconsistent among and within countries. One determining criterion forming the recommendations (e.g. 12.0 cm/hen for the EU guideline) is that all birds can feed simultaneously. However, if there are other resources in the environment, as in enriched colony housing (ECH), it is unknown whether group-housed hens will choose to feed simultaneously. This study assesses the impact of feeder space on feeding behavior of 60 laying hens (W-36) in ECH using a ultra-high frequency radio-frequency identification-based tracking system. The feeder spaces investigated were 12.0, 9.5, 8.5 and 6.5 cm/hen, achieved by blocking portions of the overall feeder access to keep hens at the same stocking density. Each feeder space treatment, randomly assigned over the course of the experiment, lasted for 7 consecutive days. Feeding behaviors were characterized as daily time spent at the feeder (TS, min/hen-day), daily frequency of visits to the feeder (FV, #/hen-day), and maximum or average percentage of hens feeding simultaneously (MPB, APB, %). Group-average daily feed intake (FI, g/hen-day), water use (WU, g/hen-day), and hen-day egg production (HDEP, %) were also measured. The results revealed that at 12.0 cm/hen, where unoccupied feeder space was present, a maximum of 59.0±1.4% (average of 31.7±0.3%) hens fed simultaneously. No significant differences were detected among 12.0, 9.5 and 8.5 cm/hen in TS (293±10, 286±10 and 281±10 min/hen-day) and MPB (59.0±1.4, 57.3±1.4 and 53.3±1.4%) (P>0.05). The outcome of no significant differences also held true between 12.0 and 9.5 cm/hen in APB (31.7±0.3 v. 30.8±0.3%) and between 9.5 and 8.5 cm/hen in all response variables measured (P>0.05). However, there were significant differences in APB between 6.5 cm/hen and all other treatments; in TS and FV between 6.5 and 9.5 cm/hen; and in MPB between 6.5 and 12 cm/hen (P0.05). The results revealed that synchronous

  11. The Use of Filter-feeders to Manage Disease in a Changing World.

    Science.gov (United States)

    Burge, Colleen A; Closek, Collin J; Friedman, Carolyn S; Groner, Maya L; Jenkins, Cody M; Shore-Maggio, Amanda; Welsh, Jennifer E

    2016-10-01

    Rapid environmental change is linked to increases in aquatic disease heightening the need to develop strategies to manage disease. Filter-feeding species are effective biofilters and can naturally mitigate disease risk to humans and wildlife. We review the role of filter-feeders, with an emphasis on bivalves, in altering disease outcomes via augmentation and reduction. Filtration can reduce transmission by removing pathogens from the water column via degradation and release of pathogens in pseudofeces. In other cases, filtration can increase pathogen transmission and disease risk. The effect of filtration on pathogen transmission depends on the selectivity of the filter-feeder, the degree of infectivity by the pathogen, the mechanism(s) of pathogen transmission and the ability of the pathogen to resist degradation. For example, some bacteria and viruses can resist degradation and accumulate within a filter-feeder leading to disease transmission to humans and other wildlife upon ingestion. Since bivalves can concentrate microorganisms, they are also useful as sentinels for the presence of pathogenic microorganisms. While somewhat less studied, other invertebrates, including ascidians and sponges may also provide ecosystem services by altering pathogen transmission. In all scenarios, climate change may affect the potential for filter-feeders to mitigate disease risk. We conclude that an assessment including empirical data and modeling of system-wide impacts should be conducted before selection of filter-feeders to mitigate disease. Such studies should consider physiology of the host and microbe and risk factors for negative impacts including augmentation of other pathogens. © The Author 2016. Published by Oxford University Press on behalf of the Society for Integrative and Comparative Biology. All rights reserved. For permissions please email: journals.permissions@oup.com.

  12. A reliable and economical method for gaining mouse embryonic fibroblasts capable of preparing feeder layers.

    Science.gov (United States)

    Jiang, Guangming; Wan, Xiaoju; Wang, Ming; Zhou, Jianhua; Pan, Jian; Wang, Baolong

    2016-08-01

    Mouse embryonic fibroblasts (MEFs) are widely used to prepare feeder layers for culturing embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs) in vitro. Transportation lesions and exorbitant prices make the commercially obtained MEFs unsuitable for long term research. The aim of present study is to establish a method, which enables researchers to gain MEFs from mice and establish feeder layers by themselves in ordinary laboratories. MEFs were isolated from ICR mouse embryos at 12.5-17.5 day post-coitum (DPC) and cultured in vitro. At P2-P7, the cells were inactivated with mitomycin C or by X-ray irradiation. Then they were used to prepare feeder layers. The key factors of the whole protocol were analyzed to determine the optimal conditions for the method. The results revealed MEFs isolated at 12.5-13.5 DPC, and cultured to P3 were the best choice for feeder preparation, those P2 and P4-P5 MEFs were also suitable for the purpose. The P3-P5 MEFs treated with 10 μg/ml of mitomycin C for 3 h, or irradiated with X-ray at 1.5 Gy/min for 25 Gy were the most suitable feeder cells. Treating MEFs with 10 μg/ml of mitomycin C for 2.5 h, 15 μg/ml for 2.0 h, or irradiating the cells with 20 Gy of X-ray at 2.0 Gy/min could all serve as alternative methods for P3-P4 cells. Our study provides a reliable and economical way to obtain large amount of qualified MEFs for long term research of ESCs or iPSCs.

  13. Mass transfer effects in feeder flow-accelerated corrosion wall thinning

    International Nuclear Information System (INIS)

    Pietralik, J.

    2008-01-01

    Flow conditions play a dominant role in Flow-Accelerated Corrosion (FAC) under certain conditions, e.g., in CANDU feeders. While chemistry and materials set the overall potential for FAC, flow conditions determine the local distribution of wall thinning. Recent plant data of feeders and laboratory tests confirms that there is a close relationship between local flow conditions, expressed by mass transfer coefficient, and FAC rate in CANDU feeder bends. The knowledge of local effects can be useful for minimizing the number of inspected components, predicting the location of the highest FAC rate for a given piping component, and determining what components or feeders should be replaced. A similar evaluation applies also to FAC in heat transfer equipment such as heat exchangers and steam generators. The objective of this paper is to examine the relationship between FAC rate and local mass transfer parameters. For FAC where the flow is dominant, the FAC rate is proportional to mass flux of ferrous ions. The mass flux is the product of the mass transfer coefficient and the concentration difference, or degree of saturation. The mass transfer coefficient describes the intensity of the transport of corrosion products (ferrous ions) from the oxide-water interface into the bulk water. Therefore, this parameter can be used for predicting the local distribution of FAC rate in the mass-transfer controlled FAC. The degree of saturation reduces the mass flux, thus reducing the FAC rate. This effect can be significant in long piping, e.g., in outlet feeders. The paper presents plant and laboratory evidence for the relationship between local mass transfer conditions and the FAC rate. It shows correlations for mass transfer coefficient in components that are highly susceptible to FAC and most important flow parameters that affect mass transfer coefficient. The role of surface roughness, wall shear stress, and local turbulence is also discussed. (author)

  14. Effects of different feeder layers on culture of bovine embryonic stem cell-like cells in vitro

    OpenAIRE

    Cong, Shan; Cao, Guifang; Liu, Dongjun

    2014-01-01

    To find a suitable feeder layer is important for successful culture conditions of bovine embryonic stem cell-like cells. In this study, expression of pluripotency-related genes OCT4, SOX2 and NANOG in bovine embryonic stem cell-like cells on mouse embryonic fibroblast feeder layers at 1–5 passages were monitored in order to identify the possible reason that bovine embryonic stem cell-like cells could not continue growth and passage. Here, we developed two novel feeder layers, mixed embryonic ...

  15. High-speed optical feeder-link system using adaptive optics

    Science.gov (United States)

    Arimoto, Yoshinori; Hayano, Yutaka; Klaus, Werner

    1997-05-01

    We propose a satellite laser communication system between a ground station and a geostationary satellite, named high- speed optical feeder link system. It is based on the application of (a) high-speed optical devices, which have been developed for ground-based high-speed fiber-optic communications, and (b) the adaptive optics which compensates wavefront distortions due to atmospheric turbulences using a real time feedback control. A link budget study shows that a system with 10-Gbps bit-rate are available assuming the state-of-the-art device performance of the Er-doped fiber amplifier. We further discuss preliminary measurement results of the atmospheric turbulence at the telescope site in Tokyo, and present current study on the design of the key components for the feeder-link laser transceiver.

  16. The effects of automated scatter feeders on captive grizzly bear activity budgets.

    Science.gov (United States)

    Andrews, Nathan L P; Ha, James C

    2014-01-01

    Although captive bears are popular zoo attractions, they are known to exhibit high levels of repetitive behaviors (RBs). These behaviors have also made them particularly popular subjects for welfare research. To date, most research on ursid welfare has focused on various feeding methods that seek to increase time spent searching for, extracting, or consuming food. Prior research indicates an average of a 50% reduction in RBs when attempts are successful and, roughly, a 50% success rate across studies. This research focused on decreasing time spent in an RB while increasing the time spent active by increasing time spent searching for, extracting, and consuming food. The utility of timed, automated scatter feeders was examined for use with captive grizzly bears (Ursis arctos horribilis). Findings include a significant decrease in time spent in RB and a significant increase in time spent active while the feeders were in use. Further, the bears exhibited a wider range of behaviors and a greater use of their enclosure.

  17. Irradiated murine fibroblasts as feeder layer used in human cell culture

    International Nuclear Information System (INIS)

    Almeida, Tiago L.; Klingbeil, Fatima G.; Yoshito, Daniele; Caproni, Priscila; Mathor, Monica B.; Herson, Marisa R.

    2007-01-01

    In 1975, Rheinwald and Green published an in vitro model for keratinocyte cell cultures in which the use of murine fibroblasts, as a feeder layer was introduced. These cells are modified fibroblasts, which presence render keratinocyte cells to remain proliferative for longer periods of time. This optimization of culture outputs has allowed for several clinical applications of confluent keratinocyte cultures as skin substitutes or wound dressings in situations such as post burn extensive skin loss, loss of oral mucosa, and other skin disorders. Nevertheless, proliferation of fibroblast in co-culture with keratinocytes must be controlled by anti-proliferative measures such as irradiation; at the same time, keratinocytes require specific nutrients in the culture medium, which may interfere with the fibroblast feeder layer viability. Therefore, the thorough understanding of the impact of different issues such as culture media composition, irradiation dose and pre-plating storage conditions of irradiated fibroblast to be used as feeder layer in these co-culture systems is important. In this work, changes as far as viability and proliferative rates of irradiated fibroblasts in culture were evaluated in relation to the type of culture medium used, dose of gamma radiation exposure, storage and timing of cell plating post irradiation. Results indicate that the type of culture medium used and time-lag between irradiation, refrigeration and plating of irradiated cells do not have significant impact in culture outcomes. However, the dose of gamma radiation administered to the cells may influence the final quality of these cells if to be used as a feeder layer. (author)

  18. Feeder use predicts both acquisition and transmission of a contagious pathogen in a North American songbird.

    Science.gov (United States)

    Adelman, James S; Moyers, Sahnzi C; Farine, Damien R; Hawley, Dana M

    2015-09-22

    Individual heterogeneity can influence the dynamics of infectious diseases in wildlife and humans alike. Thus, recent work has sought to identify behavioural characteristics that contribute disproportionately to individual variation in pathogen acquisition (super-receiving) or transmission (super-spreading). However, it remains unknown whether the same behaviours enhance both acquisition and transmission, a scenario likely to result in explosive epidemics. Here, we examined this possibility in an ecologically relevant host-pathogen system: house finches and their bacterial pathogen, Mycoplasma gallisepticum, which causes severe conjunctivitis. We examined behaviours likely to influence disease acquisition (feeder use, aggression, social network affiliations) in an observational field study, finding that the time an individual spends on bird feeders best predicted the risk of conjunctivitis. To test whether this behaviour also influences the likelihood of transmitting M. gallisepticum, we experimentally inoculated individuals based on feeding behaviour and tracked epidemics within captive flocks. As predicted, transmission was fastest when birds that spent the most time on feeders initiated the epidemic. Our results suggest that the same behaviour underlies both pathogen acquisition and transmission in this system and potentially others. Identifying individuals that exhibit such behaviours is critical for disease management. © 2015 The Author(s).

  19. Urbanization affects neophilia and risk-taking at bird-feeders

    Science.gov (United States)

    Tryjanowski, Piotr; Møller, Anders Pape; Morelli, Federico; Biaduń, Waldemar; Brauze, Tomasz; Ciach, Michał; Czechowski, Paweł; Czyż, Stanisław; Dulisz, Beata; Goławski, Artur; Hetmański, Tomasz; Indykiewicz, Piotr; Mitrus, Cezary; Myczko, Łukasz; Nowakowski, Jacek J.; Polakowski, Michał; Takacs, Viktoria; Wysocki, Dariusz; Zduniak, Piotr

    2016-06-01

    Urban environments cover vast areas with a high density of humans and their dogs and cats causing problems for exploitation of new resources by wild animals. Such resources facilitate colonization by individuals with a high level of neophilia predicting that urban animals should show more neophilia than rural conspecifics. We provided bird-feeders across urban environments in 14 Polish cities and matched nearby rural habitats, testing whether the presence of a novel item (a brightly coloured green object made out of gum with a tuft of hair) differentially delayed arrival at feeders in rural compared to urban habitats. The presence of a novel object reduced the number of great tits Parus major, but also the total number of all species of birds although differentially so in urban compared to rural areas. That was the case independent of the potentially confounding effects of temperature, population density of birds, and the abundance of cats, dogs and pedestrians. The number of great tits and the total number of birds attending feeders increased in urban compared to rural areas independent of local population density of birds. This implies that urban birds have high levels of neophilia allowing them to readily exploit unpredictable resources in urban environments.

  20. Economic Contribution of Regional Feeder Ports to The Local Economy In Indonesia

    Directory of Open Access Journals (Sweden)

    Ibnu Syabri

    2017-07-01

    Full Text Available Indonesia regional feeder ports’ main function is to serve marine transport activities between regency/city in a province in limited quantities. The intention of the government to make marine transportation as the backbone of national logistic transportation system puts these ports to an important position, as suppliers for the main and/or collector ports and as goods distribution centers for the region from the bigger ports. Not only as a provider of accessibility between regions, regional feeder ports should be seen as an investation to boost regional economy. This study aims to explain the influences of regional feeder ports on regency/city economy, based on the port types: (1 cargo ports, and (2 cargo & passengers ports. Results showed that both types of ports have positive influences on the regency/city economy, although it is not related to region’s economic base sector. Cargo ports which are mainly located on west area of Indonesia, supports the region’s economy more than cargo & passenger ports which are mainly located on the east.

  1. Resolving the architecture of monogenetic feeder systems from exposures of extinct volcanic fields

    Science.gov (United States)

    Muirhead, J.; Van Eaton, A. R.; Re, G.; White, J. D. L.; Ort, M. H.

    2016-12-01

    Monogenetic volcanic fields pose hazards to a number of major cities worldwide. During an eruption, the evolution of the intrusive feeder network modulates eruption behavior and location, as well as the warning signs of impending activity. However, historical examples of monogenetic eruptions are rare, particularly those monitored with the modern tools required to constrain the geometry and interconnectivity of subsurface intrusive feeders (e.g., InSAR, GPS). Geologic exposures in extinct fields around the Colorado Plateau provide clues to the geometry of shallow intrusions (<1000 m depth) that feed monogenetic volcanoes. We present field- and satellite-based observations of exposed intrusions in the Hopi Buttes volcanic field (Arizona), which reveal that many eruptions were fed by interconnected dike-sill systems. Results from the Hopi Buttes show that volcanic cone alignment studies are biased to the identification of dike intrusions, and thereby neglect the important contributions of sills to shallow feeder systems. For example, estimates of intruded volumes in fields exhumed by uplift and erosion in Utah and Arizona show that sills make up 30 - 92% of the shallow intruded volume within 1000 m of the paleosurface. By transporting magma toward and away from eruptive conduits, these sills likely played a role in modulating eruption styles (e.g., explosive vs effusive) and controlling lateral vent migrations. Sill transitions at Hopi Buttes would have produced detectable surface uplifts, and illustrate the importance of geological studies for informing interpretations of geodetic and seismological data during volcanic crises.

  2. Manufacture and test of prototype water pipe chase barrier in ITER Magnet Feeder system

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Kun, E-mail: lukun@ipp.ac.cn [Institute of Plasma Physics, Shushan Hu Road 350, Hefei, Anhui (China); Wen, Xinjie; Liu, Chen; Song, Yuntao [Institute of Plasma Physics, Shushan Hu Road 350, Hefei, Anhui (China); Niu, Erwu [ITER China, 15B Fuxing Road, Beijing 100862 (China); Gung, Chenyu; Su, Man [ITER Organization, Route de Vinon-sur-Verdon – CS 90046, 13067 St Paul-lez-Durance Cedex (France)

    2016-11-01

    The Magnet Feeder system in the International Thermonuclear Experimental Reactor (ITER) deploys electrical currents and supercritical helium to the superconducting magnets and the magnet diagnostic signals to the operators. In the current design, the feeders located in the upper L3 level of the Tokamak gallery penetrate the Tokamak coolant water system vault, the biological shield and the cryostat. As a secondary confinement to contain the activated coolant water in the vault in the case of water pipe burst accident, a water barrier is welded between the penetration in the water pipe chase outer wall and the mid-plane of the vacuum jacket of the Feeder Coil Terminal Box (CTB). A thin-wall stainless steel diaphragm with an omega shape profile is welded around the CTB as the water barrier to endure 2 bar hydraulic pressure. In addition, the barrier is designed as a flexible compensator to withstand a maximum of 15 mm of axial displacement of the CTB in case of helium leak accident without failure. This paper presents the detail configuration, the manufacturing and assembly processes of the water barrier. Test results of the prototype water barrier under simulated accident conditions are also reported. Successful qualification of the design and manufacturing process of the water barrier lays a good foundation for the series production of this subsystem.

  3. Identification of molecules derived from human fibroblast feeder cells that support the proliferation of human embryonic stem cells

    DEFF Research Database (Denmark)

    Anisimov, Sergey V.; Christophersen, Nicolaj S.; Correia, Ana S.

    2011-01-01

    The majority of human embryonic stem cell lines depend on a feeder cell layer for continuous growth in vitro, so that they can remain in an undifferentiated state. Limited knowledge is available concerning the molecular mechanisms that underlie the capacity of feeder cells to support both...... the proliferation and pluripotency of these cells. Importantly, feeder cells generally lose their capacity to support human embryonic stem cell proliferation in vitro following long-term culture. In this study, we performed large-scale gene expression profiles of human foreskin fibroblasts during early...... foreskin fibroblasts to serve as feeder cells for human embryonic stem cell cultures. Among these, the C-KIT, leptin and pigment epithelium-derived factor (PEDF) genes were the most interesting candidates....

  4. BODY SIZE AND HAREM SIZE IN MALE RED-WINGED BLACKBIRDS: MANIPULATING SELECTION WITH SEX-SPECIFIC FEEDERS.

    Science.gov (United States)

    Rohwer, Sievert; Langston, Nancy; Gori, Dave

    1996-10-01

    We experimentally manipulated the strength of selection in the field on red-winged blackbirds (Agelaius phoeniceus) to test hypotheses about contrasting selective forces that favor either large or small males in sexually size dimorphic birds. Selander (1972) argued that sexual selection favors larger males, while survival selection eventually stabilizes male size because larger males do not survive as well as smaller males during harsh winters. Searcy (1979a) proposed instead that sexual selection may be self limiting: male size might be stabilized not by overwinter mortality, but by breeding-season sexual selection that favors smaller males. Under conditions of energetic stress, smaller males should be able to display more and thus achieve higher reproductive success. Using feeders that provisioned males or females but not both, we produced conditions that mimicked the extremes of natural conditions. We found experimental support for the hypothesis that when food is abundant, sexual selection favors larger males. But even under conditions of severe energetic stress, smaller males did not gain larger harems, as the self-limiting hypothesis predicted. Larger males were more energetically stressed than smaller males, but in ways that affected their future reproductive output rather than their current reproductive performance. Stressed males that returned had smaller wings and tails than those that did not return; among returning stressed males, relative harem sizes were inversely related to wing and tail length. Thus, male body size may be stabilized not by survival costs during the non-breeding season, nor by energetic costs during the breeding season, but by costs of future reproduction that larger males pay for their increased breeding-season effort. © 1996 The Society for the Study of Evolution.

  5. Replacement of murine fibroblasts by human fibroblasts irradiated in obtaining feeder layer for the culture of human keratinocytes

    International Nuclear Information System (INIS)

    Yoshito, Daniele; Sufi, Bianca S.; Santin, Stefany P.; Mathor, Monica B.; Altran, Silvana C.; Isaac, Cesar

    2011-01-01

    Human autologous epithelia cultivated in vitro, have been used successfully in treating damage to skin integrity. The methodology allowed the cultivation of these epithelia was described by Rheinwald and Green in 1975, this methodology consisted in seeding keratinocytes onto a feeder layer composed of lineage 3T3 murine fibroblasts, the proliferation rate is controlled through the action of ionizing radiation. However, currently there is a growing concern about the possibility of transmitting prions and murine viruses to transplanted patients. Taking into account this concern, in this present work, we replaced the feeder layer originally composed of murine fibroblasts by human fibroblasts. To obtain this new feeder layer was necessary to standardize the enough irradiation dose to inhibit the replication of human fibroblasts and the verification of effectiveness of the development of keratinocytes culture on a feeder layer thus obtained. According to the obtained results we can verify that the human fibroblasts irradiated at various tested doses (60, 70, 100, 200, 250 and 300 Gy) had their mitotic activity inactivated by irradiation, allowing the use of any of these doses to confection of the feeder layer, since these fibroblasts irradiated still showed viable until fourteen days of cultivation. In the test of colony formation efficiency was observed that keratinocytes seeded on irradiated human fibroblasts were able to develop satisfactorily, preserving their clonogenic potential. Therefore it was possible the replacement of murine fibroblasts by human fibroblasts in confection of the feeder layer, in order to eliminate this xenobiotic component of the keratinocytes culture. (author)

  6. Fabrication of corneal epithelial cell sheets maintaining colony-forming cells without feeder cells by oxygen-controlled method.

    Science.gov (United States)

    Nakajima, Ryota; Takeda, Shizu

    2014-01-01

    The use of murine 3T3 feeder cells needs to be avoided when fabricating corneal epithelial cell sheets for use in treating ocular surface diseases. However, the expression level of the epithelial stem/progenitor cell marker, p63, is down-regulated in feeder-free culture systems. In this study, in order to fabricate corneal epithelial cell sheets that maintain colony-forming cells without using any feeder cells, we investigated the use of an oxygen-controlled method that was developed previously to fabricate cell sheets efficiently. Rabbit limbal epithelial cells were cultured under hypoxia (1-10% O2) and under normoxia during stratification after reaching confluence. Multilayered corneal epithelial cell sheets were fabricated using an oxygen-controlled method, and immunofluorescence analysis showed that cytokeratin 3 and p63 was expressed in appropriate localization in the cell sheets. The colony-forming efficiency of the cell sheets fabricated by the oxygen-controlled method without feeder cells was significantly higher than that of cell sheets fabricated under 20% O2 without feeder cells. These results indicate that the oxygen-controlled method has the potential to achieve a feeder-free culture system for fabricating corneal epithelial cell sheets for corneal regeneration. Copyright © 2013 Elsevier Ltd. All rights reserved.

  7. Replacement of murine fibroblasts by human fibroblasts irradiated in obtaining feeder layer for the culture of human keratinocytes

    Energy Technology Data Exchange (ETDEWEB)

    Yoshito, Daniele; Sufi, Bianca S.; Santin, Stefany P.; Mathor, Monica B. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Altran, Silvana C.; Isaac, Cesar [Universidade Sao Paulo (USP), Sao Paulo, SP (Brazil). Fac. de Medicina. Lab. de Microcirurgia Plastica; Esteves-Pedro, Natalia M. [Universidade Sao Paulo (USP), Sao Paulo, SP (Brazil). Fac. de Ciencias Farmaceuticas. Lab. de Controle Biologico; Herson, Marisa R. [DonorTissue Bank of Victoria (Australia)

    2011-07-01

    Human autologous epithelia cultivated in vitro, have been used successfully in treating damage to skin integrity. The methodology allowed the cultivation of these epithelia was described by Rheinwald and Green in 1975, this methodology consisted in seeding keratinocytes onto a feeder layer composed of lineage 3T3 murine fibroblasts, the proliferation rate is controlled through the action of ionizing radiation. However, currently there is a growing concern about the possibility of transmitting prions and murine viruses to transplanted patients. Taking into account this concern, in this present work, we replaced the feeder layer originally composed of murine fibroblasts by human fibroblasts. To obtain this new feeder layer was necessary to standardize the enough irradiation dose to inhibit the replication of human fibroblasts and the verification of effectiveness of the development of keratinocytes culture on a feeder layer thus obtained. According to the obtained results we can verify that the human fibroblasts irradiated at various tested doses (60, 70, 100, 200, 250 and 300 Gy) had their mitotic activity inactivated by irradiation, allowing the use of any of these doses to confection of the feeder layer, since these fibroblasts irradiated still showed viable until fourteen days of cultivation. In the test of colony formation efficiency was observed that keratinocytes seeded on irradiated human fibroblasts were able to develop satisfactorily, preserving their clonogenic potential. Therefore it was possible the replacement of murine fibroblasts by human fibroblasts in confection of the feeder layer, in order to eliminate this xenobiotic component of the keratinocytes culture. (author)

  8. A feeder-free culture using autogeneic conditioned medium for undifferentiated growth of human embryonic stem cells: Comparative expression profiles of mRNAs, microRNAs and proteins among different feeders and conditioned media

    Directory of Open Access Journals (Sweden)

    Chou Chi-Hsien

    2010-10-01

    Full Text Available Abstract Background Human embryonic stem (hES cell lines were derived from the inner cell mass of human blastocysts, and were cultured on mouse embryonic fibroblast (MEF feeder to maintain undifferentiated growth, extensive renewal capacity, and pluripotency. The hES-T3 cell line with normal female karyotype was previously used to differentiate into autogeneic fibroblast-like cells (T3HDF as feeder to support the undifferentiated growth of hES-T3 cells (T3/HDF for 14 passages. Results A feeder-free culture on Matrigel in hES medium conditioned by the autogeneic feeder cells (T3HDF was established to maintain the undifferentiated growth of hES-T3 cells (T3/CMHDF for 8 passages in this investigation. The gene expression profiles of mRNAs, microRNAs and proteins between the undifferentiated T3/HDF and T3/CMHDF cells were shown to be very similar, and their expression profiles were also found to be similar to those of T3/MEF and T3/CMMEF cells grown on MEF feeder and feeder-free Matrigel in MEF-conditioned medium, respectively. The undifferentiated state of T3/HDF and T3/CMHDF as well as T3/MEF andT3/CMMEF cells was evidenced by the very high expression levels of "stemness" genes and low expression levels of differentiation markers of ectoderm, mesoderm and endoderm in addition to the strong staining of OCT4 and NANOG. Conclusion The T3HDF feeder and T3HDF-conditioned medium were able to support the undifferentiated growth of hES cells, and they would be useful for drug development and toxicity testing in addition to the reduced risks of xenogeneic pathogens when used for medical applications such as cell therapies.

  9. Meta-analysis on the effects of the physical environment, animal traits, feeder and feed characteristics on the feeding behaviour and performance of growing-finishing pigs.

    Science.gov (United States)

    Averós, X; Brossard, L; Dourmad, J Y; de Greef, K H; Edwards, S A; Meunier-Salaün, M C

    2012-08-01

    A meta-analysis, using information from 45 experiments on growing-finishing pigs published in 39 manuscripts, was carried out to determine the simultaneous effects of the physical environment (space allowance, group size, flooring conditions, temperature, presence of enrichment), pig traits (initial body weight (BW) for each studied time interval, sex, genetics), feeder characteristics (water provision within the feeder, feeder design (individual/collective), feeder places/pig, presence of feeder protection) and feed characteristics (feed allowance (ad libitum/restricted), net energy content, crude protein (CP) content), as well as their potential interactions, on the feeding behaviour and performance of growing-finishing pigs. The detrimental effect of low temperature on performance was particularly evident for restricted-fed pigs (P < 0.05). At reduced feeder space allowance, a reduction in the percentage of time spent eating was predicted when increasing initial BW, whereas the opposite was predicted for larger feeder space allowances (P < 0.001). The reduction in visit duration to the feeder in higher BW groups became gradually more important with increasing feeder space allowance (P < 0.01), whereas the increase in the ingestion rate and average daily feed intake (ADFI) with increasing initial BW became smaller with increasing feeder space (P < 0.05). The model predicted a reduction in feed conversion ratio (FCR) with increasing group size (P < 0.05) and floor space allowance (P < 0.01) and on solid floors with or without bedding (P < 0.05). In comparison with other feeders, wet/dry feeders were associated with more frequent but shorter feeder visits (P < 0.05), higher ingestion rates (P < 0.001) and higher ADFI (P < 0.10). The use of protection within individual feeders increased the time spent feeding (P < 0.001), reduced the number of visits per day (P < 0.01), the ingestion rate (P < 0.001) and FCR (P < 0.01) in comparison with other feeder types. Sex

  10. Tumorigenic risk of human induced pluripotent stem cell explants cultured on mouse SNL76/7 feeder cells

    Energy Technology Data Exchange (ETDEWEB)

    Kamada, Mizuna; Mitsui, Youji, E-mail: y-mitsui8310@hb.tp1.jp; Kumazaki, Tsutomu; Kawahara, Yuta; Matsuo, Taira; Takahashi, Tomoko, E-mail: t-takahashi@kph.bunri-u.ac.jp

    2014-10-24

    Highlights: • hiPS cell explants formed malignant tumors when SNL76/7 feeder cells were used. • Multi type tumors developed by interaction of SNL76/7 feeder cells with hiPS cells. • Tumorigenic risk occurs by co-culture of hiPS cells with SNL76/7 feeder cells. - Abstract: The potential for tumor formation from transplanted human induced pluripotent stem cell (hiPSC) derivatives represents a high risk in their application to regenerative medicine. We examined the genetic origin and characteristics of tumors, that were formed when 13 hiPSC lines, established by ourselves, and 201B7 hiPSC from Kyoto University were transplanted into severe combined immune-deficient (SCID) mice. Though teratomas formed in 58% of mice, five angiosarcomas, one malignant solitary fibrous tumor and one undifferentiated pleomorphic sarcoma formed in the remaining mice. Three malignant cell lines were established from the tumors, which were derived from mitomycin C (MMC)-treated SNL76/7 (MMC-SNL) feeder cells, as tumor development from fusion cells between MMC-SNL and hiPSCs was negative by genetic analysis. While parent SNL76/7 cells produced malignant tumors, neither MMC-SNL nor MMC-treated mouse embryo fibroblast (MEF) produced malignant tumors. When MMC-SNL feeder cells were co-cultured with hiPSCs, growing cell lines were generated, that expressed genes similar to the parent SNL76/7 cells. Thus, hiPSCs grown on MMC-SNL feeder cells have a high risk of generating feeder-derived malignant tumors. The possible mechanism(s) of growth restoration and the formation of multiple tumor types are discussed with respect of the interactions between MMC-SNL and hiPSC.

  11. Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells.

    Science.gov (United States)

    Yamashita, Tomoko; Miyamoto, Yuki; Bando, Yoshio; Ono, Takashi; Kobayashi, Sakurako; Doi, Ayano; Araki, Toshihiro; Kato, Yosuke; Shirakawa, Takayuki; Suzuki, Yutaka; Yamauchi, Junji; Yoshida, Shigetaka; Sato, Naoya

    2017-01-01

    Oligodendrocytes myelinate axons and form myelin sheaths in the central nervous system. The development of therapies for demyelinating diseases, including multiple sclerosis and leukodystrophies, is a challenge because the pathogenic mechanisms of disease remain poorly understood. Primate pluripotent stem cell-derived oligodendrocytes are expected to help elucidate the molecular pathogenesis of these diseases. Oligodendrocytes have been successfully differentiated from human pluripotent stem cells. However, it is challenging to prepare large amounts of oligodendrocytes over a short amount of time because of manipulation difficulties under conventional primate pluripotent stem cell culture methods. We developed a proprietary dissociated monolayer and feeder-free culture system to handle pluripotent stem cell cultures. Because the dissociated monolayer and feeder-free culture system improves the quality and growth of primate pluripotent stem cells, these cells could potentially be differentiated into any desired functional cells and consistently cultured in large-scale conditions. In the current study, oligodendrocyte progenitor cells and mature oligodendrocytes were generated within three months from monkey embryonic stem cells. The embryonic stem cell-derived oligodendrocytes exhibited in vitro myelinogenic potency with rat dorsal root ganglion neurons. Additionally, the transplanted oligodendrocyte progenitor cells differentiated into myelin basic protein-positive mature oligodendrocytes in the mouse corpus callosum. This preparative method was used for human induced pluripotent stem cells, which were also successfully differentiated into oligodendrocyte progenitor cells and mature oligodendrocytes that were capable of myelinating rat dorsal root ganglion neurons. Moreover, it was possible to freeze, thaw, and successfully re-culture the differentiating cells. These results showed that embryonic stem cells and human induced pluripotent stem cells maintained in a

  12. Handling system for nuclear fuel cans to a fuel pellet feeder

    International Nuclear Information System (INIS)

    Vere, B.; Mathevon, P.

    1985-01-01

    The handling system comprises a first array of conveyors which takes a batch of casings from a delivery rack, alters the spacing between the casings, and delivers them to a vibrating table feeder, a second array of conveyors which readjusts the spacing between casing to its initial value and transfers the casings to a removal rack, and automatic and synchronized control means for ensuring the displacements of casings always in the same direction. The increase of spacing between casings can be used, before feeding, to allow them to be weighed one after the other, and after feeding, for cleaning the end part of fuel cans [fr

  13. Evaluation of the cryogenic mechanical properties of the insulation material for ITER Feeder superconducting joint

    Science.gov (United States)

    Wu, Zhixiong; Huang, Rongjin; Huang, ChuanJun; Yang, Yanfang; Huang, Xiongyi; Li, Laifeng

    2017-12-01

    The Glass-fiber reinforced plastic (GFRP) fabricated by the vacuum bag process was selected as the high voltage electrical insulation and mechanical support for the superconducting joints and the current leads for the ITER Feeder system. To evaluate the cryogenic mechanical properties of the GFRP, the mechanical properties such as the short beam strength (SBS), the tensile strength and the fatigue fracture strength after 30,000 cycles, were measured at 77K in this study. The results demonstrated that the GFRP met the design requirements of ITER.

  14. Research on communication system of underground safety management based on leaky feeder cable

    Institute of Scientific and Technical Information of China (English)

    CHEN Jian-hong; ZHANG Tao; CHENG Yun-cai; ZHANG Han

    2007-01-01

    According to the current working status of underground safety management and production scheduling, the importance and existed problem of underground mine radio communication were summarized, and the basic principle and classification of leaky feeder cable were introduced and the characteristics of cable were analyzed specifically in depth, and the application model of radio communication system for underground mine safety management was put forward. Meanwhile, the research explanation of the system component, function and evaluation was provided. The discussion result indicates that communication system of underground mine safety management which is integrated two-way relay amplifier and other equipment has many communication functions, and underground mine mobile communication can be achieved well.

  15. The Linehaul-Feeder Vehicle Routing Problem with Virtual Depots and Time Windows

    Directory of Open Access Journals (Sweden)

    Huey-Kuo Chen

    2011-01-01

    Full Text Available This paper addresses the linehaul-feeder vehicle routing problem with virtual depots and time windows (LFVRPTW. Small and large vehicles deliver services to customers within time constraints; small vehicles en route may reload commodities from either the physical depot or from the larger vehicle at a virtual depot before continuing onward. A two-stage solution heuristic involving Tabu search is proposed to solve this problem. The test results show that the LFVRPTW performs better than the vehicle routing problem with time windows in terms of both objective value and the number of small vehicles dispatched.

  16. Modeling and Control of Low Voltage Flexible Units for Enhanced Operation of Distribution Feeders

    DEFF Research Database (Denmark)

    Raboni, Pietro; Hu, Weihao; Chaudhary, Sanjay

    2013-01-01

    In some networks Distributed Generators (DGs) are phasing out conventional power plants in terms of power production but still large efforts are required for providing ancillary services. In this paper the usage of fast response units like a Micro Turbines (MT) and a stationary Electric Vehicle...... Battery (EVB) is proposed for providing primary regulation in grid connected mode and for hierarchically manage an islanded LV distribution feeder. The unit models are described and a novel EVB model directly based on manufacturer’s data is proposed and evaluated comparing its performances with Sim...

  17. "The good into the pot, the bad into the crop!"--a new technology to free stem cells from feeder cells.

    Directory of Open Access Journals (Sweden)

    Annette Schneider

    Full Text Available A variety of embryonic and adult stem cell lines require an initial co-culturing with feeder cells for non-differentiated growth, self renewal and maintenance of pluripotency. However for many downstream ES cell applications the feeder cells have to be considered contaminations that might interfere not just with the analysis of experimental data but also with clinical application and tissue engineering approaches. Here we introduce a novel technique that allows for the selection of pure feeder-freed stem cells, following stem cell proliferation on feeder cell layers. Complete and reproducible separation of feeder and embryonic stem cells was accomplished by adaptation of an automated cell selection system that resulted in the aspiration of distinct cell colonies or fraction of colonies according to predefined physical parameters. Analyzing neuronal differentiation we demonstrated feeder-freed stem cells to exhibit differentiation potentials comparable to embryonic stem cells differentiated under standard conditions. However, embryoid body growth as well as differentiation of stem cells into cardiomyocytes was significantly enhanced in feeder-freed cells, indicating a feeder cell dependent modulation of lineage differentiation during early embryoid body development. These findings underline the necessity to separate stem and feeder cells before the initiation of in vitro differentiation. The complete separation of stem and feeder cells by this new technology results in pure stem cell populations for translational approaches. Furthermore, a more detailed analysis of the effect of feeder cells on stem cell differentiation is now possible, that might facilitate the identification and development of new optimized human or genetically modified feeder cell lines.

  18. Vertical linear feeder to elliptical igneous saucer-shaped sills: evidences from structural observations, geochemistry and experimental modeling

    Science.gov (United States)

    Galerne, C. Y.; Galland, O.; Neumann, E. R.; Planke, S.

    2009-12-01

    The structural relationships between sills and their feeders are poorly documented because they are rarely observed in the field and difficult to image on seismic data. For instance, it is unclear whether sills are fed by pipes, dikes or other sills. Nevertheless, the geometrical relationships between sills and their feeders provide first-order constraints on magma emplacement mechanisms. Here, we investigate the structural and geochemical relationships between sills and potential feeder dikes in a remarkably well-preserved and exposed sill complex, the Golden Valley Sill Complex (GVSC), Karoo Basin, South Africa. The GVSC consists of five major saucer-shaped sills and six dikes. The Golden Valley sill itself is an elliptical saucer, with a N-S trend. A one meter thick dike (D4) crops out underneath the southern tip of the Golden Valley sill. The strike of this dike is parallel to the long axis of the Golden Valley sill. Detailed sampling and geochemical analyses of the GVSC show that each sill and dike exhibits a specific geochemical signature. The Golden Valley sill and its underlying dike D4 have identical signatures. Although there is no clear structural evidence, the consistent geometrical and geochemical relationships between the Golden Valley sill and the D4 dike suggest that this vertical linear structure is the feeder of the overlying saucer-shaped sill. In order to investigate the relationships between sills and feeders, we resorted to scaled laboratory experiments. The experiments consisted of a low-viscosity vegetable oil representing magma and a cohesive fine-grained silica flour representing brittle rocks. We placed a horizontal weak layer into the silica flour, just above the top of the inlet, to simulate strata. Such a weak layer controlled the formation of horizontal sill that subsequently turned into a transgressive sheet leading to the formation of a saucer geometry. We ran experiments with varying inlet shapes: 1) a point inlet representing a

  19. Assessing the role of benthic filter feeders on phytoplankton production in a shellfish farming site: Mont Saint Michel Bay, France

    Science.gov (United States)

    Cugier, Philippe; Struski, Caroline; Blanchard, Michel; Mazurié, Joseph; Pouvreau, Stéphane; Olivier, Frédéric; Trigui, Jihane R.; Thiébaut, Eric

    2010-07-01

    The macrobenthic community of Mont Saint Michel Bay (English Channel, France) is mainly dominated by filter feeders, including cultivated species (oysters and mussels). An ecological model of the bay was developed, coupling a 2D hydro-sedimentary model and two biological models for primary production and filter-feeder filtration. The filter-feeder model includes three cultivated species ( Mytilus edulis, Crassostrea gigas and Ostrea edulis), one invasive species ( Crepidula fornicata) and eight wild native species ( Abra alba, Cerastoderma edule, Glycymeris glycymeris, Lanice conchilega, Macoma balthica, Paphia rhomboides, Sabellaria alveolata, andSpisula ovalis). For cultivated and invasive species, the production of biodeposits was computed to assess their role in restimulating primary production. Chlorophyll a concentrations appeared to be strongly controlled by the filter feeders. When the pressure of each benthic compartment on phytoplankton was estimated separately wild species and the invasive slipper limpet C.fornicata were shown to be key elements in the control of primary production. Conversely, the role of cultivated species, particularly oysters, was weaker. Feedback due to the mineralization of biodeposits also appears to be crucial to fully evaluate the role of filter feeders in primary production.

  20. Effect of portion size and milk flow on the use of a milk feeder and the development of cross-sucking in dairy calves

    DEFF Research Database (Denmark)

    Nielsen, Per Peetz; Jensen, Margit Bak; Halekoh, Ulrich

    2018-01-01

    milk feeder in each pen, and exposed to four milk-feeding treatments in a cross-over design with four periods of 1 week. All four treatments involved a daily allowance of 8. L of whole milk, with variation in the maximum portion size and the rate at which milk entered the teat of the milk feeder......This study aimed to investigate whether reducing the milk flow and increasing the milk portion size of a computer-controlled milk feeder would lead to less cross-sucking and fewer unrewarded feeder visits in dairy calves. Five groups, each with 9 or 10 calves (n = 48), were housed in pens with one...

  1. Manufacture and testing of the CTB&SBB thermal shield for the ITER magnet feeder system

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Kun; Liu, Chen; Song, Yuntao; Feng, Hansheng; Ding, Kaizhong, E-mail: kzding@ipp.ac.cn; Wang, Tanbin; Ji, Hui

    2015-10-15

    The system of International Thermonuclear Experimental Reactor (ITER) feeders is responsible for the power, helium cooling, and instrumentation of the magnets of the coil terminal box and S-bend box (CTB&SBB) thermal shield outside the cryostat. An 80-K rectangular Al thermal shield is hung inside the CTB&SBB to reduce the thermal radiation heat loads of 4.5-K helium. The American Society of Interventional Pain Physicians (ASIPP) will supply all the 31 sets of feeders for ITER. A manufactured prototype of CTB&SBB thermal shield is first quality-tested before the commencement of the series production. First, a detailed configuration of the rectangular Al thermal shield is presented in this article. The paper also presents more information on the manufacturing process of the thermal shield, especially the welding process, the procedure for ensuring good weld quality, and the use of a specially designed tool to ensure <5-mm deformation on such a 7.3-m-long thermal shield during welding. In addition, the cold test and results, including the cooling process with 13-bar and 17.5-g/s 80-K He gas, and the temperature distribution on different panels of the thermal shield are presented. The whole process of manufacture and testing lays a good foundation for the series production of the thermal shield.

  2. Photovoltaic Hosting Capacity of Feeders with Reactive Power Control and Tap Changers

    Energy Technology Data Exchange (ETDEWEB)

    Ceylan, Oğuzhan; Paudyal, Sumit; Bhattarai, Bishnu P.; Myers, Kurt S.

    2017-06-01

    This paper proposes an algorithm to determine photovoltaic (PV) hosting capacity of power distribution networks as a function of number of PV injection nodes, reactive power support from the PVs, and the sub-station load tap changers (LTCs). In the proposed method, several minute by minute simulations are run based on randomly chosen PV injection nodes, daily PV output profiles, and daily load profiles from a pool of high-resolution realistic data set. The simulation setup is built using OpenDSS and MATLAB. The performance of the proposed method is investigated in the IEEE 123-node distribution feeder for multiple scenarios. The case studies are performed particularly for one, two, five and ten PV injection nodes, and looking at the maximum voltage deviations. Case studies show that the PV hosting capacity of the 123-node feeder greatly differs with the number of PV injection nodes. We have also observed that the PV hosting capacity increases with reactive power support and higher tap position of sub-station LTC.

  3. Stability-index based method for optimal Var planning in distribution feeders

    International Nuclear Information System (INIS)

    Hamouda, Abdellatif; Zehar, Khaled

    2011-01-01

    Research highlights: → Optimal Var planning is modelled using heuristic methods. → Capacitor sizes and location are determined by a two stage method. → Capacitor locations are determined using nodes stability-indices. → Their sizes are calculated subject to a new constraint on the branches reactive currents. → The solution is fast and leads to better results without over compensation. -- Abstract: The problem of the reactive energy optimal planning can be solved in a fast and efficient way using heuristic techniques. The latter reduce the number of the control variables to be determined and lead to a near global optimal solution. The capacitor appropriate locations are firstly determined by decisive indices then, their optimal sizes are calculated. In this paper a stability-index based method is presented. The nodes stability-indices are calculated for identifying the most sensitive nodes to be candidate for receiving near optimal standard capacitors that, reduce the feeder power losses, improve the voltage profile and maximise the economic saving (objective function). In this multi-objective optimisation problem, the commonly used voltage constraint is substituted by a new constraint on the branch reactive currents. This new constraint, allows overcoming the over compensation phenomenon by setting positive branch reactive currents. The solution is further improved by regulating the source node voltage. The proposed approach has been tested on several feeder examples and its effectiveness has been demonstrated through comparative studies. The obtained results have shown that the proposed approach leads to a promising and feasible solution.

  4. Stability-index based method for optimal Var planning in distribution feeders

    Energy Technology Data Exchange (ETDEWEB)

    Hamouda, Abdellatif, E-mail: a_hamouda1@yahoo.f [QUERE Laboratory, Optics and Mechanics Institut, University Ferhat Abbas, Setif 19000 (Algeria); Zehar, Khaled [QUERE Laboratory, Department of Electrical and Electronics Engineering, University of Bahrain, Isa Town (Bahrain)

    2011-05-15

    Research highlights: {yields} Optimal Var planning is modelled using heuristic methods. {yields} Capacitor sizes and location are determined by a two stage method. {yields} Capacitor locations are determined using nodes stability-indices. {yields} Their sizes are calculated subject to a new constraint on the branches reactive currents. {yields} The solution is fast and leads to better results without over compensation. -- Abstract: The problem of the reactive energy optimal planning can be solved in a fast and efficient way using heuristic techniques. The latter reduce the number of the control variables to be determined and lead to a near global optimal solution. The capacitor appropriate locations are firstly determined by decisive indices then, their optimal sizes are calculated. In this paper a stability-index based method is presented. The nodes stability-indices are calculated for identifying the most sensitive nodes to be candidate for receiving near optimal standard capacitors that, reduce the feeder power losses, improve the voltage profile and maximise the economic saving (objective function). In this multi-objective optimisation problem, the commonly used voltage constraint is substituted by a new constraint on the branch reactive currents. This new constraint, allows overcoming the over compensation phenomenon by setting positive branch reactive currents. The solution is further improved by regulating the source node voltage. The proposed approach has been tested on several feeder examples and its effectiveness has been demonstrated through comparative studies. The obtained results have shown that the proposed approach leads to a promising and feasible solution.

  5. Effect of Antimicrobial Dosage Regimen on Salmonella and Escherichia coli Isolates from Feeder Swine▿

    Science.gov (United States)

    Wagner, Bruce A.; Straw, Barbara E.; Fedorka-Cray, Paula J.; Dargatz, David A.

    2008-01-01

    A body of evidence exists that suggests that antimicrobial use in food animals leads to resistance in both pathogenic and commensal bacteria. This study focused on the impact of three different antimicrobial regimes (low-level continuous, pulse, and no antimicrobial) for two antimicrobials (chlortetracycline and tylosin) on the presence of Salmonella spp. and on the prevalence of antimicrobial resistance of both Salmonella spp. and nonspecific Escherichia coli in fecal samples from feeder swine. The prevalence of fecal samples positive for Salmonella spp. significantly decreased between the samples taken at feeder placement compared to samples taken when the animals were close to market weight. Differences in resistance of Salmonella spp. did not appear to be influenced by dosing treatment including the control. Analysis of antimicrobial resistance examining both susceptibility and resistance, as well as MIC outcomes, demonstrated that only resistance to cephalothin increased in E. coli under the pulse chlortetracycline treatment. These results suggest that the dosing regimes examined in this study did not lead to an increase in either the prevalence of Salmonella spp. or the prevalence of antimicrobial resistance in isolates of Salmonella spp. or E. coli. PMID:18223115

  6. Surgical management of dural arteriovenous fistulas with transosseous arterial feeders involving the jugular bulb.

    Science.gov (United States)

    Tirakotai, W; Benes, L; Kappus, C; Sure, U; Farhoud, A; Bien, S; Bertalanffy, H

    2007-01-01

    Dural arteriovenous fistulas located in the vicinity of the jugular foramen are complex vascular malformations and belong to the most challenging skull base lesions to treat. The authors comprehensively analyze multiple features in a series of dural arteriovenous fistulas with transosseous arterial feeders involving the jugular bulb. Four patients who underwent surgery via the transcondylar approach to treat dural arteriovenous fistulas around the jugular foramen were retrospectively reviewed. Previously, endovascular treatment was attempted in all patients. The success of the surgical treatment was examined with postoperative angiography. Complete obliteration of the dural arteriovenous fistulas (DAVFs) was achieved in three patients, and significant flow reduction in one individual. All patients had a good postoperative outcome, and only one experienced mild hypoglossal nerve palsy. Despite extensive bone drilling, an occipitocervical fusion was necessary in only one patient with bilateral lesions. The use of an individually tailored transcondylar approach to treat dural arteriovenous fistulas at the region of the jugular foramen is most effective. This approach allows for complete obliteration of the connecting arterial feeders, and removal of bony structures containing pathological vessels.

  7. Supervisory control and data acquisition system development for superconducting current feeder system of SST-1

    International Nuclear Information System (INIS)

    Patel, R.; Mahesuria, G.; Gupta, N.C.; Sonara, D.; Panchal, R.; Panchal, P.; Tanna, V.L.; Pradhan, S.

    2014-01-01

    The Current Feeders System (CFS) is essentially an optimized bridge between the power supply at room temperature and Super Conducting Magnet System (SCMS) of the SST-1 machine at 4.5 K.CFS is a complex electrical and cryogenic network which consists of ten pairs of 10 KA rating helium Vapor cooled Conventional Current Leads (VCCLs), superconducting (SC) current feeder and associated components. For the safe and reliable operation of CFS, it is equipped with different physical process parameters measuring instruments like flow, pressure, temperature, level, vacuum, voltage taps and final control element like control valves, heaters, vacuum pumps etc. PLC program is developed in ladder language for acquiring and controlling the process parameters. Independent SCADA applications developed in WonderwareIntouch software for data communication from PLC, front-end Graphical User Interface (GUI), auto-manual interface, real time trends, history trends, events and alarm pages. Time synchronized communication established between CFS control system and Industrial SQL server (InSQL) Historian for centralized storage of CFS process parameters which intern provides the CFS process data to SST-1 central control room. SCADA based data acquisition and data retrieval system is found to be satisfactory during the recent SST-1 cool down experiment. This paper describes the SCADA and PLC application development and their communication to InSQL server. (author)

  8. Enhanced Particle Swarm Optimization-Based Feeder Reconfiguration Considering Uncertain Large Photovoltaic Powers and Demands

    Directory of Open Access Journals (Sweden)

    Ying-Yi Hong

    2014-01-01

    Full Text Available The Kyoto protocol recommended that industrialized countries limit their green gas emissions in 2012 to 5.2% below 1990 levels. Photovoltaic (PV arrays provide clear and sustainable renewable energy to electric power systems. Solar PV arrays can be installed in distribution systems of rural and urban areas, as opposed to wind-turbine generators, which cause noise in surrounding environments. However, a large PV array (several MW may incur several operation problems, for example, low power quality and reverse power. This work presents a novel method to reconfigure the distribution feeders in order to prevent the injection of reverse power into a substation connected to the transmission level. Moreover, a two-stage algorithm is developed, in which the uncertain bus loads and PV powers are clustered by fuzzy-c-means to gain representative scenarios; optimal reconfiguration is then achieved by a novel mean-variance-based particle swarm optimization. The system loss is minimized while the operational constraints, including reverse power and voltage variation, are satisfied due to the optimal feeder reconfiguration. Simulation results obtained from a 70-bus distribution system with 4 large PV arrays validate the proposed method.

  9. A single-cell and feeder-free culture system for monkey embryonic stem cells.

    Science.gov (United States)

    Ono, Takashi; Suzuki, Yutaka; Kato, Yosuke; Fujita, Risako; Araki, Toshihiro; Yamashita, Tomoko; Kato, Hidemasa; Torii, Ryuzo; Sato, Naoya

    2014-01-01

    Primate pluripotent stem cells (PSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), hold great potential for research and application in regenerative medicine and drug discovery. To maximize primate PSC potential, a practical system is required for generating desired functional cells and reproducible differentiation techniques. Much progress regarding their culture systems has been reported to date; however, better methods would still be required for their practical use, particularly in industrial and clinical fields. Here we report a new single-cell and feeder-free culture system for primate PSCs, the key feature of which is an originally formulated serum-free medium containing FGF and activin. In this culture system, cynomolgus monkey ESCs can be passaged many times by single-cell dissociation with traditional trypsin treatment and can be propagated with a high proliferation rate as a monolayer without any feeder cells; further, typical PSC properties and genomic stability can be retained. In addition, it has been demonstrated that monkey ESCs maintained in the culture system can be used for various experiments such as in vitro differentiation and gene manipulation. Thus, compared with the conventional culture system, monkey ESCs grown in the aforementioned culture system can serve as a cell source with the following practical advantages: simple, stable, and easy cell maintenance; gene manipulation; cryopreservation; and desired differentiation. We propose that this culture system can serve as a reliable platform to prepare primate PSCs useful for future research and application.

  10. Eddy current array probe for detection of surface breaking cracks in the extrados of feeder bends

    International Nuclear Information System (INIS)

    Obrutsky, L.S.; Cassidy, R.A.; Chaplin, K.; Martin, P.; Bureau, J.F.

    2006-01-01

    A new eddy current array probe has been implemented as a straightforward and promising technique for detection of outer diameter (OD) surface-breaking cracks on the extrados of feeder bends. The design is based on previous work performed at AECL, which had demonstrated that eddy current probes with laterally displaced transmit-receive coils can overcome some of the limitations of inspecting ferritic steel components for surface-breaking cracks. The Feeder Integrity Joint Program-CANDU Owners Group Inc. (FIJP-COG) Non-Destructive Evaluation (NDE) Team members commissioned AECL to work in collaboration with the probe manufacturer ZETEC, to develop a field usable eddy current array probe. The objective was to acquire a technique with the following capabilities: fast scanning non-contact inspection technique for surface breaking discontinuities; full inspection of the bend extrados OD surface in a single scan; ability to inspect first and second bends with similar settings and capabilities; permanent record for future reference; axial and circumferential crack detection in a single scan; capability to detect OD surface-breaking cracks, which can provide additional information to that provided by ultrasonic testing (UT) for flaw characterization, and detection threshold: Surface breaking cracks equivalent to a 0.5 mm deep, 10 mm long EDM notch located on the OD of the bend extrados. This paper discusses the basis for probe design, summarizes the experimental work to evaluate probe capabilities and analyzes the results from the field trial. (author)

  11. Eddy current array probe for detection of surface breaking cracks in the extrados of feeder bends

    Energy Technology Data Exchange (ETDEWEB)

    Obrutsky, L.S.; Cassidy, R.A.; Chaplin, K. [Atomic Energy of Canada Limited, Chalk River, Ontario (Canada)]. E-mail: obrutskyl@aecl.ca; Martin, P. [NB Power, Point Lepreau NGS, Point Lepreau, New Brunswick (Canada)]. E-mail: PMartin@nbpower.com; Bureau, J.F. [Zetec, Quebec, Quebec (Canada)]. E-mail: jean-francois.bureau@zetec.com

    2006-07-01

    A new eddy current array probe has been implemented as a straightforward and promising technique for detection of outer diameter (OD) surface-breaking cracks on the extrados of feeder bends. The design is based on previous work performed at AECL, which had demonstrated that eddy current probes with laterally displaced transmit-receive coils can overcome some of the limitations of inspecting ferritic steel components for surface-breaking cracks. The Feeder Integrity Joint Program-CANDU Owners Group Inc. (FIJP-COG) Non-Destructive Evaluation (NDE) Team members commissioned AECL to work in collaboration with the probe manufacturer ZETEC, to develop a field usable eddy current array probe. The objective was to acquire a technique with the following capabilities: fast scanning non-contact inspection technique for surface breaking discontinuities; full inspection of the bend extrados OD surface in a single scan; ability to inspect first and second bends with similar settings and capabilities; permanent record for future reference; axial and circumferential crack detection in a single scan; capability to detect OD surface-breaking cracks, which can provide additional information to that provided by ultrasonic testing (UT) for flaw characterization, and detection threshold: Surface breaking cracks equivalent to a 0.5 mm deep, 10 mm long EDM notch located on the OD of the bend extrados. This paper discusses the basis for probe design, summarizes the experimental work to evaluate probe capabilities and analyzes the results from the field trial. (author)

  12. Design of Two Feeder Three Phase Four Wire Distribution System Utilizing Multi Converter UPQC with Fuzzy Logic Controller

    Directory of Open Access Journals (Sweden)

    Chandra Babu Paduchuri

    2014-01-01

    Full Text Available This paper proposes the instantaneous p-q theory based fuzzy logic controller (FLC for multi converter unified power quality conditioner (MC-UPQC to mitigate power quality issues in two feeders three-phase four-wire distribution systems. The proposed system is extended system of the existing one feeder three-phase four-wire distribution system, which is operated with UPQC. This system is employed with three voltage source converters, which are connected commonly to two feeder distribution systems. The performance of this proposed system used to compensate voltage sag, neutral current mitigation and compensation of voltage and current harmonics under linear and nonlinear load conditions. The neutral current flowing in series transformers is zero in the implementation of the proposed system. The simulation performance analysis is carried out using MATLAB.

  13. Applicability of ANSYS ELBOW290 element for flexibility calculation of tight radius bends on feeder pipes in CANDU reactors

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, X., E-mail: Xuan.Zhang@candu.com [Candu Energy Inc, Mississauga, ON (Canada)

    2015-07-01

    A curved pipe element, ELBOW290, became available in ANSYS 12. This element was developed based on a simplified shell theory, and maintains the ability to capture cross-sectional deformations of elbows. Numerical testing on the applicability of this element for the flexibility calculation of the tight radius bends in CANDU reactors is carried out to determine the usability of this element in completing stress analyses for feeder pipes. Comparisons are made between the ELBOW290 and the shell element for various feeder bend types found in domestic and overseas CANDU reactors. The comparisons show that the ELBOW290 element is suitable for calculating the flexibility of the tight radius bends. (author)

  14. The use of multiple imputation for the accurate measurements of individual feed intake by electronic feeders.

    Science.gov (United States)

    Jiao, S; Tiezzi, F; Huang, Y; Gray, K A; Maltecca, C

    2016-02-01

    Obtaining accurate individual feed intake records is the key first step in achieving genetic progress toward more efficient nutrient utilization in pigs. Feed intake records collected by electronic feeding systems contain errors (erroneous and abnormal values exceeding certain cutoff criteria), which are due to feeder malfunction or animal-feeder interaction. In this study, we examined the use of a novel data-editing strategy involving multiple imputation to minimize the impact of errors and missing values on the quality of feed intake data collected by an electronic feeding system. Accuracy of feed intake data adjustment obtained from the conventional linear mixed model (LMM) approach was compared with 2 alternative implementations of multiple imputation by chained equation, denoted as MI (multiple imputation) and MICE (multiple imputation by chained equation). The 3 methods were compared under 3 scenarios, where 5, 10, and 20% feed intake error rates were simulated. Each of the scenarios was replicated 5 times. Accuracy of the alternative error adjustment was measured as the correlation between the true daily feed intake (DFI; daily feed intake in the testing period) or true ADFI (the mean DFI across testing period) and the adjusted DFI or adjusted ADFI. In the editing process, error cutoff criteria are used to define if a feed intake visit contains errors. To investigate the possibility that the error cutoff criteria may affect any of the 3 methods, the simulation was repeated with 2 alternative error cutoff values. Multiple imputation methods outperformed the LMM approach in all scenarios with mean accuracies of 96.7, 93.5, and 90.2% obtained with MI and 96.8, 94.4, and 90.1% obtained with MICE compared with 91.0, 82.6, and 68.7% using LMM for DFI. Similar results were obtained for ADFI. Furthermore, multiple imputation methods consistently performed better than LMM regardless of the cutoff criteria applied to define errors. In conclusion, multiple imputation

  15. Feeders of Free-Roaming Cats: Personal Characteristics, Feeding Practices, and Data on Cat Health and Welfare in an Urban Setting of Israel.

    Science.gov (United States)

    Gunther, Idit; Raz, Tal; Even Zor, Yehonatan; Bachowski, Yuval; Klement, Eyal

    2016-01-01

    Cat feeders serve as an important source of available food for free-roaming cats (FRCs) and can play a central role in providing data on FRC distribution, welfare, and health. Data on cat feeder personalities as well as a better understanding of their feeding practices offer relevance for decision making concerning FRC population control strategies. The current study surveyed 222 FRC feeders who responded to a municipal trap-neuter-return (TNR) campaign in an Israeli central urban setting. The aim of the study was to describe their personal characteristics, feeding practices, and the FRC populations they feed. Feeders were divided into four groups according to the number of cats they claimed to feed per day (group 1: fed up to 5 cats, group 2: fed 6-10 cats, group 3: fed 11-20 cats, and group 4: fed ≥21 cats). Most feeders were women (81%), with a median age of 58 years (range 18-81). The feeders reported an overall feeding of 3337 cats in 342 different feeding locations. Feeders of group 4 comprised 15.31% (n = 34) of all feeders but fed 56% (n = 1869) of the FRC in 37.42% (n = 128) of the feeding locations. "Heavy" feeders (groups 3 and 4) reported that they traveled significantly longer distances in order to feed the cats. Commercial dry food consisted of 90% of the food they provided, with 66% of them feeding once a day, with less food per cat per day than the other feeder groups. Interestingly, "heavy" feeders were usually singles, had on average fewer siblings, a clear preference for owning cats as pets, and lived in lower income neighborhoods. According to the feeders' reports on the FRC populations they fed, 69.7% (2325/3337) cats were neutered and 11.8% (395/3337) were kittens. In addition, they reported that 1.6% (54/3337) of the cats were limping, 2% (67/3337) suffered from a systemic disease, 4% (135/3337) had skin lesions, and 3.9% (130/3337) were suffering from a chronic disability. Abundance of kittens and morbidity rate were

  16. Effect of feeders in 3D modeling of low impedance multilayer CPW transmission line

    Science.gov (United States)

    Zaini, R. I.; Kyabaggu, P. B. K.; Sinulingga, E. P.

    2018-02-01

    Improved characteristics with low dissipation loss MMICs are highly desirable for wireless communications. However, the current industrial MMIC design is mainly based on microstrip concept which suffered from parasitic and unwanted phenomenon especially at higher frequency (>20 GHz). On the other hand, for future wireless technology, higher frequency operation is required and on-wafer microwave characterizations as well as precise modeling of 3D Multilayer CPW components are vital. This project concerns with understanding of the microwave characteristics behavior of Multilayer CPW components in MMIC applications. Feeder effect as unwanted parts in the characteristics has been investigated to determine its relation with the half wavelength resonance of the Multilayer CPW Low Impedance Transmission Line.

  17. A Survey of Pesticide Accumulation in a Specialist Feeder, the Koala (Phascolarctos cinereus).

    Science.gov (United States)

    Marschner, Caroline; Higgins, Damien P; Krockenberger, Mark B

    2017-09-01

    To maintain profitability in Australia's agricultural and urban landscapes pesticides are used throughout the range of koala habitats. The koala is a specialist feeder, reliant on metabolic enzyme capacities to utilise a toxic diet of eucalypt leaves and is potentially prone to adverse effects when xenobiotic interactions between dietary and anthropogenic xenobiotics occur. The aim of this study was to investigate accumulation of frequently used pesticides in wild koalas in 4 areas of New South Wales and Queensland. Liver samples of 57 deceased koalas were collected from care facilities and analysed using a modified QuEChERS extraction method followed by GCMSMS, HRLCMS and LCMSMS. No accumulation of any of the 166 investigated pesticides was found. Data indicate hepatic accumulation of pesticides in this species is uncommon even with close interactions with intensive land use. Despite the lack of hepatic bioaccumulation, this study cannot exclude a direct effect on hepatocellular metabolic pathways.

  18. Complete nutrient content of four species of commercially available feeder insects fed enhanced diets during growth.

    Science.gov (United States)

    Finke, Mark D

    2015-11-01

    Commercially raised feeder insects used to feed captive insectivores are a good source of many nutrients but are deficient in several key nutrients. Current methods used to supplement insects include dusting and gut-loading. Here, we report on the nutrient composition of four species of commercially raised feeder insects fed a special diet to enhance their nutrient content. Crickets, mealworms, superworms, and waxworms were analyzed for moisture, crude protein, fat, ash, acid detergent fiber, total dietary fiber, minerals, amino acids, fatty acids, vitamins, taurine, carotenoids, inositol, and cholesterol. All four species contained enhanced levels of vitamin E and omega 3 fatty acids when compared to previously published data for these species. Crickets, superworms, and mealworms contained β-carotene although using standard conversion factors only crickets and superworms would likely contain sufficient vitamin A activity for most species of insectivores. Waxworms did not contain any detectable β-carotene but did contain zeaxanthin which they likely converted from dietary β-carotene. All four species contained significant amounts of both inositol and cholesterol. Like previous reports all insects were a poor source of calcium and only superworms contained vitamin D above the limit of detection. When compared to the nutrient requirements as established by the NRC for growing rats or poultry, these species were good sources of most other nutrients although the high fat and low moisture content of both waxworms and superworms means when corrected for energy density these two species were deficient in more nutrients than crickets or mealworms. These data show the value of modifying the diet of commercially available insects as they are growing to enhance their nutrient content. They also suggest that for most insectivores properly supplemented lower fat insects such as crickets, or smaller mealworms should form the bulk of the diet. © 2015 The Authors. Zoo Biology

  19. The impact of deprivation on youth violence: a comparison of cities and their feeder towns.

    Science.gov (United States)

    Jones, S J; Sivarajasingam, V; Shepherd, J

    2011-06-01

    66,000 children and adolescents are treated at emergency departments (EDs) in England and Wales each year for assault injury. The aim of this study was to compare adolescent assault injury rates in cities and towns and determine how assault injury varies with deprivation and gender. The study was set in three cities in Wales, UK, and their surrounding towns. Subjects were 11-17 year olds treated for assault injury at one of seven EDs from 1 October 2005 to 30 September 2006. Area of residence (electoral divisions, EDivs) was identified from patient postcode. EDivs were aggregated into deprivation fifths for males and females and cities and towns. Assault injury rates, rate ratios and 95% CIs were calculated. 1472 children and adolescents of 11-17 years old were treated for assault injury. Male city assault injury rates were 14.2/1000 11-17 year olds; and 13.1 in towns. Female city assault injury rates were 6.0; and 5.6 in towns. In the most deprived city areas males had assault injury rates 2.6 times (95% CI 1.85 to 3.59) that of the most affluent, compared with 2.0 times in towns (95% CI 1.39 to 2.86). For females, the most deprived city areas had assault injury rates 5.3 times that of the most affluent (95% CI 2.93 to 9.41), compared with 2.8 times in towns (95% CI 1.47 to 5.28). Injury in youth violence increased with increasing deprivation in cities and their feeder towns. This was true for boys and girls, though rates for boys were consistently higher. This link between assault injury and deprivation was stronger for girls in cities than in feeder towns. Strategies to prevent youth violence need to include improved safeguarding arrangements for girls living in the most deprived city areas.

  20. USULAN PERBAIKAN OPERATION POINT SHEET PADA MESIN FEEDER AIDA 1100 PT. XXX DENGAN MENGGUNAKAN METODE SMED

    Directory of Open Access Journals (Sweden)

    Ary Arvianto

    2012-02-01

    Full Text Available Single Minute Exchange of Die (SMED merupakan salah satu alat lean yang penting untuk mengurangi waste dan meningkatkan fleksibilitas dalam proses manufaktur yang memungkinkan dalam pengurangan ukuran lot dan perbaikan aliran manufaktur. SMED mengurangi waktu non-produktif dengan mempersatukan dan standardisasi operasi dalam pergantian alat, dengan menggunakan teknik sederhana dan aplikasi yang mudah. Namun proses tersebut tidak dapat memberikan hasil yang  spesifik dalam pelaksanaannya, dimana masih dapat dilakukan suatu perbaikan. Untuk mengatasi hal ini, data statistik dan alat-alat teknik industri dapat diintegrasikan dalam pendekatan SMED untuk meningkatkan hasil penerapan SMED. Penerapan pendekatan SMED yang diusulkan diuji untuk mesin feeder didalam industri otomotif PT. XXX. Implementasi ini memungkinkan adanya pengurangan waktu setup, melalui reorganisasi sumber daya internal perusahaan tanpa membutuhkan investasi yang signifikan.   Kata kunci: Lean manufacturing systems, Single Minute Exchange of Die, Quick ChangeOver.     Single Minute Exchange of Die (SMED is one of the essential lean tools to reduce waste and increase flexibility in manufacturing processes that enable the reduction of lot size and improving manufacturing flow. SMED reduces non-productive time by streamlining and standardizing operations in the turn of the tool, using simple techniques and easy application. But the process can not provide a specific result in the implementation, which can still be an improvement. To overcome this, statistical data and tools can be integrated in industrial engineering approaches to improve outcomes SMED SMED implementation. The proposed application of SMED approach was tested for the automotive industry in the feeder machine PT. XXX. This implementation allows for the reduction of setup time, through the reorganization of the company's internal resources without requiring significant investment. Keywords: Lean manufacturing

  1. Urban and rural habitats differ in number and type of bird feeders and in bird species consuming supplementary food.

    Science.gov (United States)

    Tryjanowski, Piotr; Skórka, Piotr; Sparks, Tim H; Biaduń, Waldemar; Brauze, Tomasz; Hetmański, Tomasz; Martyka, Rafał; Indykiewicz, Piotr; Myczko, Łukasz; Kunysz, Przemysław; Kawa, Piotr; Czyż, Stanisław; Czechowski, Paweł; Polakowski, Michał; Zduniak, Piotr; Jerzak, Leszek; Janiszewski, Tomasz; Goławski, Artur; Duduś, Leszek; Nowakowski, Jacek J; Wuczyński, Andrzej; Wysocki, Dariusz

    2015-10-01

    Bird feeding is one of the most widespread direct interactions between man and nature, and this has important social and environmental consequences. However, this activity can differ between rural and urban habitats, due to inter alia habitat structure, human behaviour and the composition of wintering bird communities. We counted birds in 156 squares (0.25 km(2) each) in December 2012 and again in January 2013 in locations in and around 26 towns and cities across Poland (in each urban area, we surveyed 3 squares and also 3 squares in nearby rural areas). At each count, we noted the number of bird feeders, the number of bird feeders with food, the type of feeders, additional food supplies potentially available for birds (bread offered by people, bins) and finally the birds themselves. In winter, urban and rural areas differ in the availability of food offered intentionally and unintentionally to birds by humans. Both types of food availability are higher in urban areas. Our findings suggest that different types of bird feeder support only those species specialized for that particular food type and this relationship is similar in urban and rural areas.

  2. Establishment of feeder-free culture system for human induced pluripotent stem cell on DAS nanocrystalline graphene

    Science.gov (United States)

    Lee, Hyunah; Nam, Donggyu; Choi, Jae-Kyung; Araúzo-Bravo, Marcos J.; Kwon, Soon-Yong; Zaehres, Holm; Lee, Taehee; Park, Chan Young; Kang, Hyun-Wook; Schöler, Hans R.; Kim, Jeong Beom

    2016-02-01

    The maintenance of undifferentiated human pluripotent stem cells (hPSC) under xeno-free condition requires the use of human feeder cells or extracellular matrix (ECM) coating. However, human-derived sources may cause human pathogen contamination by viral or non-viral agents to the patients. Here we demonstrate feeder-free and xeno-free culture system for hPSC expansion using diffusion assisted synthesis-grown nanocrystalline graphene (DAS-NG), a synthetic non-biological nanomaterial which completely rule out the concern of human pathogen contamination. DAS-NG exhibited advanced biocompatibilities including surface nanoroughness, oxygen containing functional groups and hydrophilicity. hPSC cultured on DAS-NG could maintain pluripotency in vitro and in vivo, and especially cell adhesion-related gene expression profile was comparable to those of cultured on feeders, while hPSC cultured without DAS-NG differentiated spontaneously with high expression of somatic cell-enriched adhesion genes. This feeder-free and xeno-free culture method using DAS-NG will facilitate the generation of clinical-grade hPSC.

  3. Feeder-cell-independent culture of the pig-embryonic-stem-cell-derived exocrine pancreatic cell line, PICM-31

    Science.gov (United States)

    The adaptation to feeder-independent growth of a pig embryonic stem cell-derived pancreatic cell line is described. The parental PICM-31 cell line, previously characterized as an exocrine pancreas cell line, was colony-cloned two times in succession resulting in the subclonal cell line, PICM-31A1. P...

  4. 47 CFR 25.147 - Licensing provision for NGSO MSS feeder downlinks in the band 6700-6875 MHz.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Licensing provision for NGSO MSS feeder downlinks in the band 6700-6875 MHz. 25.147 Section 25.147 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES SATELLITE COMMUNICATIONS Applications and Licenses Space...

  5. Developmental Competence of Buffalo (Bubalus bubalis) Pluripotent Embryonic Stem Cells Over Different Homologous Feeder Layers and the Comparative Evaluation with Various Extracellular Matrices.

    Science.gov (United States)

    Sharma, Manjinder; Dubey, Pawan K; Kumar, Rajesh; Nath, Amar; Kumar, G Sai; Sharma, G Taru

    2013-05-01

    Use of somatic cells as a feeder layer to maintain the embryonic stem cells (ESCs) in undifferentiated state limits the stem cell research design, since experimental data may result from a combined ESCs and feeder cell response to various stimuli. Therefore, present study was designed to evaluate the developmental competence of the buffalo ESCs over different homogenous feeders and compare with various extracellular matrices using different concentrations of LIF. Inner cell masses (ICMs) of in vitro hatched blastocysts were cultured onto homologous feeders viz. fetal fibroblast, granulosa and oviductal cell feeder layers and synthetic matrices viz. fibronectin, collagen type I and matrigel in culture medium. Developmental efficiency was found higher for ESCs cultured on fetal fibroblast and granulosa layers (83.33%) followed by fibronectin (77.78%) at 30 ng LIF. Oviductal feeder was found to be the least efficient feeder showing only 11.11% undifferentiated primary ESC colonies at 30 ng LIF. However, neither feeder layer nor synthetic matrix could support the development of primary colonies at 10 ng LIF. Expression of SSEA- 4, TRA-1-60 and Oct-4 were found positive in ESC colonies from all the feeders and synthetic matrices with 20 ng and 30 ng LIF. Fetal fibroblast and granulosa cell while, amongst synthetic matrices, fibronectin were found to be equally efficient to support the growth and maintenance of ESCs pluripotency with 30 ng LIF. This well-defined culture conditions may provide an animal model for culturing human embryonic stem cells in the xeno-free or feeder-free conditions for future clinical applications.

  6. Cone-Beam Computed Tomography (CBCT) Hepatic Arteriography in Chemoembolization for Hepatocellular Carcinoma: Performance Depicting Tumors and Tumor Feeders

    Energy Technology Data Exchange (ETDEWEB)

    Lee, In Joon [National Cancer Center, Department of Radiology (Korea, Republic of); Chung, Jin Wook, E-mail: chungjw@snu.ac.kr; Yin, Yong Hu; Kim, Hyo-Cheol; Kim, Young Il; Jae, Hwan Jun; Park, Jae Hyung [Seoul National University College of Medicine, Seoul National University Hospital, Department of Radiology (Korea, Republic of)

    2015-10-15

    PurposeThis study was designed to analyze retrospectively the performance of cone-beam computed tomography (CBCT) hepatic arteriography in depicting tumors and their feeders and to investigate the related determining factors in chemoembolization for hepatocellular carcinoma (HCC).MethodsEighty-six patients with 142 tumors satisfying the imaging diagnosis criteria of HCC were included in this study. The performance of CBCT hepatic arteriography for chemoembolization per tumor and per patient was evaluated using maximum intensity projection images alone (MIP analysis) or MIP combined with multiplanar reformation images (MIP + MPR analysis) regarding the following three aspects: tumor depiction, confidence of tumor feeder detection, and trackability of tumor feeders. Tumor size, tumor enhancement, tumor location, number of feeders, diaphragmatic motion, portal vein enhancement, and hepatic artery to parenchyma enhancement ratio were regarded as potential determining factors.ResultsTumors were depicted in 125 (88.0 %) and 142 tumors (100 %) on MIP and MIP + MPR analysis, respectively. Imaging performances on MIP and MIP + MPR analysis were good enough to perform subsegmental chemoembolization without additional angiographic investigation in 88 (62.0 %) and 128 tumors (90.1 %) on per-tumor basis and in 43 (50 %) and 73 (84.9 %) on per-patient basis, respectively. Significant determining factors for performance in MIP + MPR analysis on per tumor basis were tumor size (p = 0.030), tumor enhancement (0.005), tumor location (p = 0.001), and diaphragmatic motion (p < 0.001).ConclusionsCBCT hepatic arteriography provided sufficient information for subsegmental chemoembolization by depicting tumors and their feeders in the vast majority of patients. Combined analysis of MIP and MPR images was essential to enhance the performance of CBCT hepatic arteriography.

  7. Flow visualization study of two-phase flow in a single bend outlet feeder pipe of a CANDU reactor

    International Nuclear Information System (INIS)

    Savalaxs, S.-A.; Lister, D.H.; Steward, F.R.

    2005-01-01

    In CANDU reactors, the feeder piping that is used to direct the high-temperature water coolant between the fuel channels and the steam generators is made of carbon steel. Since 1996, several CANDU stations have reported excessive corrosion of their outlet feeders. The first metre is particularity vulnerable because the piping there consists of single or double bends, which have relatively thin walls produced by the bending process. Early studies related the attack to the hydrodynamics of the coolant and verified that it was a type of flow-accelerated corrosion. In order to understand the hydrodynamics of the coolant in the outlet feeders by flow visualization, a full-scale transparent test section simulating the geometry and orientation of an outlet feeder bend with its upstream components was fabricated. The feeder consisted of a 54 mm diameter acrylic pipe with a 73 degree bend. This was connected to the upstream component with an acrylic simulation of a Grayloc flanged fitting. A test loop supplied room temperature water to the test section at flow rates up to 0.019 m3/s. Air could be injected into the water to give a mean volume fraction of up to 0.56. In this preliminary investigation, the size and velocity of air bubbles at different flow conditions and their distribution within the pipe bend were studied. Particular attention was paid to the flow pattern at the inside of the bend, where a CFD (computational fluid dynamics) code - Fluent 6.1-had failed to predict a liquid film in an earlier study. A high-speed digital video camera was used to determine the relation between bubble size and velocity. Such a relation should help to explain the discrepancy in the CFD modelling and provide the basis for accurate predictions of phase distribution in complex geometries at high flow rates. (authors)

  8. Effect of artificial feeders on pollen loads of the hummingbirds of Cerro de La Muerte, Costa Rica

    Directory of Open Access Journals (Sweden)

    Gerardo Avalos

    2012-03-01

    Full Text Available Although sugar-water feeders are commonly used by enthusiasts to attract hummingbirds, little is known about how they affect hummingbird behavior and flower use. We studied the highland hummingbird assemblage of Cerro de La Muerte, Costa Rica, both at a site with permanent feeders (La Georgina Restaurant and further from it. We examined how feeder use and monopolization affected seasonal changes in pollen loads during four sampling periods, including dry and wet seasons, from 2003-2005. We expected that species monopolizing the feeders would carry little or no pollen whatsoever, and would have pollen loads characterized by low floral diversity, in contrast with species less dependent on feeders. We obtained pollen samples from 183 individuals of four hummingbird species captured around the feeders using mist nets, which were compared with a pollen reference collection of plants with a pollination syndrome by hummingbirds. The same methods were implemented at a site 3km away from the feeders. Feeder usage was quantified by counting the number of times hummingbirds drank from the feeders in periods of 4min separated by 1min. The effects of hummingbird species and season on pollen load categories were assessed using a nominal logistic regression. The alpha species at the site, the Fiery-throated Hummingbird (Panterpe insignis, dominated the feeders during the dry season. Meanwhile, in the wet season, feeder usage was more evenly distributed across species, with the exception of the Volcano Hummingbird, Selasphorus flammula, which occupies the last place in the dominance hierarchy. Pollen loads of hummingbirds captured near feeders were low in abundance (more than 50% of captured individuals had zero or low pollen loads, and low in species richness (96% of the hummingbirds with pollen from only one plant genus, Centropogon. Overall pollen loads increased during the dry season coinciding with peaks in flower availability, although the majority of

  9. Field evaluation of cutter and feeder mechanism of chickpea harvester for lentil harvesting

    Directory of Open Access Journals (Sweden)

    S Kamgar

    2016-09-01

    Full Text Available Introduction The main producers of lentil are Canada, India, Nepal and China, respectively and Iran is the ninth producer in the world. The hand pulling is the usual method of lentil harvesting. Use of conventional combine because of short leg varieties, wide combine head in dry land and grain losses by cutter bar vibrations is impossible. So a mechanism should be designed to harvest the lentil plants with minimum damage. This mechanism should be evaluated under different tests of crop and machines such as forward speed (FS, grain moisture content (GMC, different varieties and other parameters. Some researchers studied the effects of GMC (Andrews and et al., 1993; Huitink, 2005; Adisa, 2009; Abdi and Jalali, 2013 and FS on grain losses (Geng et al., 1984; Swapan et al., 2001; Mostafavand and Kamgar, 2014; Hunt, 1995. Field tests were conducted at three levels of FS 1.5, 3 and 4.5 km.h-1; three levels of cutting height (CH 4, 8 and 13 cm and two levels of GMC, 8 and 14% on two varieties of lentils including Flip and Shiraz with three replications. Materials and Methods The feeder and cutter mechanism for chickpea harvesting that was the base design of device which is notched wheel and counter shear, was used. The other components of device were dividers, slat and chain feeders, belt and pulleys, chassis, elevator conveyor and storage. Two split plot design based on a randomized complete design was used to determine the effects of above treatments on lentil losses. Results and Discussion The ANOVA results indicated that the all studied factors; FS of feeder and cutter mechanism, CH and GMC had significant effect on losses of Shiraz variety (P0.05. The ranges of losses of Flip variety at 8% GMC were 8.6 to 10% for FS of 1.5 km.h-1, 9.1 to 10.4% for FS of 3 km.h-1and 10.4 to 11.4% for FS of 4.5 km h-1. These ranges at 14% GMC were 7.9 to 8.9% for FS of 1.5 km.h-1, 8.4 to 9.2% for FS of 3 km.h-1and 8.5 to 10% for FS of 4.5 km h-1. The ranges of

  10. [Effects of prefrontal ablations on the reaction of the active choice of feeder under different probability and value of the reinforcement on dog].

    Science.gov (United States)

    Preobrazhenskaia, L A; Ioffe, M E; Mats, V N

    2004-01-01

    The role of the prefrontal cortex was investigated on the reaction of the active choice of the two feeders under changes value and probability reinforcement. The experiments were performed on 2 dogs with prefrontal ablation (g. proreus). Before the lesions the dogs were taught to receive food in two different feeders to conditioned stimuli with equally probable alimentary reinforcement. After ablation in the inter-trial intervals the dogs were running from the one feeder to another. In the answer to conditioned stimuli for many times the dogs choose the same feeder. The disturbance of the behavior after some times completely restored. In the experiments with competition of probability events and values of reinforcement the dogs chose the feeder with low-probability but better quality of reinforcement. In the experiments with equal value but different probability the intact dogs chose the feeder with higher probability. In our experiments the dogs with prefrontal lesions chose the each feeder equiprobably. Thus in condition of free behavior one of different functions of the prefrontal cortex is the reactions choose with more probability of reinforcement.

  11. Utilization of human amniotic mesenchymal cells as feeder layers to sustain propagation of human embryonic stem cells in the undifferentiated state.

    Science.gov (United States)

    Zhang, Kehua; Cai, Zhe; Li, Yang; Shu, Jun; Pan, Lin; Wan, Fang; Li, Hong; Huang, Xiaojie; He, Chun; Liu, Yanqiu; Cui, Xiaohui; Xu, Yang; Gao, Yan; Wu, Liqun; Cao, Shanxia; Li, Lingsong

    2011-08-01

    Human embryonic stem (ES) cells are usually maintained in the undifferentiated state by culturing on feeder cells layers of mouse embryonic fibroblasts (MEFs). However, MEFs are not suitable to support human ES cells used for clinical purpose because of risk of zoonosis from animal cells. Therefore, human tissue-based feeder layers need to be developed for human ES cells for clinical purpose. Hereof we report that human amniotic mesenchymal cells (hAMCs) could act as feeder cells for human ES cells, because they are easily obtained and relatively exempt from ethical problem. Like MEFs, hAMCs could act as feeder cells for human ES cells to grow well on. The self-renewal rate of human ES cells cultured on hAMCs feeders was higher than that on MEFs and human amniotic epithelial cells determined by measurement of colonial diameters and growth curve as well as cell cycle analysis. Both immunofluorescence staining and immunoblotting showed that human ES cells cultured on hAMCs expressed stem cell markers such as Oct-3/4, Sox2, and NANOG. Verified by embryoid body formation in vitro and teratoma formation in vivo, we found out that after 20 passages of culture, human ES cells grown on hAMCs feeders could still retain the potency of differentiating into three germ layers. Taken together, our data suggested hAMCs may be safe feeder cells to sustain the propagation of human ES cells in undifferentiated state for future therapeutic use.

  12. Using automated feeders to wean calves fed large amounts of milk according to their ability to eat solid feed.

    Science.gov (United States)

    de Passillé, Anne Marie; Rushen, Jeffrey

    2016-05-01

    Dairy calves weaned off milk at an early age show signs of hunger and can lose weight. We examined whether using automated feeders to wean calves according to individual voluntary solid feed intake reduced the effects of weaning. Female Holstein calves were housed in groups of 5 to 9. All calves were fed 12 L/d milk and ad libitum grain starter and hay from automated feeders immediately after grouping, and were allocated to 3 weaning strategies: (1) early-weaned (EW; n=14): weaning began on d 40, and milk allowance gradually decreased until weaning was complete on d 48; (2) late-weaned (LW; n=14): weaning began on d 80 and was completed on d 89; (3) weaned by starter intake (WSI; n=28): weaning began when calves consumed 200g/d of starter and was completed when the calves consumed 1,400g/d. Each day, the automated feeders recorded quantities of milk, starter, and hay eaten by all calves, as well as the frequency of visits to the milk feeder; we used unrewarded visit frequency as a sign of hunger. Body weights (BW) were recorded weekly. We estimated daily digestible energy (DE) intake for each calf based on the milk, hay, and starter consumed. Average daily gains (ADG) were expressed as percent of BW. For calves in WSI, weaning began at 54.7±18.9 d (mean ± SD) of age, the duration of weaning was 21.1±10.6 d, and weaning ended at 75.8±10.7 d of age. Both LW and WSI calves had better ADG from wk 3 to 13 than EW calves. Calves in the WSI group drank less milk and ate more starter than LW calves but had similar ADG. During the period of weaning, EW calves made more unrewarded visits to the milk feeder than LW and WSI calves. Three EW calves lost weight during weaning, whereas all LW and WSI calves gained weight. Calves differ greatly in when they begin to eat solid feed and how quickly they increase the intake in response to a decrease in milk allowance. An advantage of automated feeders is that calves can be weaned at variable ages depending on their ability and

  13. Challenges associated with the current processes for ultrasonic inspection of CANDU reactor feeder piping

    Energy Technology Data Exchange (ETDEWEB)

    Machowski, C. [Babcock & Wilcox Canada Ltd., Cambridge, Ontario (Canada)

    2012-07-01

    CANDU® PHT Feeder Piping is generally constructed from SA106 Grade B carbon steel, which is known to be susceptible to flow accelerated corrosion when exposed to certain environmental conditions. The configuration of the CANDU reactor promotes thinning of the inside surface of the pipe walls, predominantly at the outlet feeders. Inspection of this piping is currently conducted using ultrasonic techniques and is governed by the requirements established by the CANDU Owners Group (COG). There are many challenges associated with these inspections as a result of the complexity of the reactor piping configuration. Geometrical anomalies on the surface of the pipe and non-circular geometries at the tight radius bends hinder the performance of conventional ultrasonic techniques. This can cause lost signals in areas of interest, which in turn often results in rework in order to satisfy the inspection requirements and justify fitness for service of these components. There are also many inspection sites which have limited access due to physical restrictions on the reactor face; therefore in order to maximize the performance of an inspection campaign, it is paramount that the inspection personnel and the inspection technology be well integrated through training simulations prior to execution. These inspection challenges increase the complexity of the analysis process as ultrasonic signals get distorted and lost as a result of non-circular pipe geometries. In order to ensure a high level of integrity in the analysis results, a conservative process is utilized in which two analysts independently examine the data, and a third analyst reviews their results and submits the final call. A Data Management Software application (DMS) is used to input and store the three analysis results. Another important function of the DMS is to provide a communication link between the different work-groups associated with the inspection activities. The focus of this presentation discusses:

  14. On the preparation of fire-wood splitting machines equipped with feeder devices

    International Nuclear Information System (INIS)

    Jaeaeskelaeinen, M.

    1995-01-01

    As part of the Bionergy research programme, the TTS Institute's Department of Forestry conducted a study on firewood splitting machines manufactured by Bilke Oy and Peurala Oy. The said machines are the first of their kind in Finland to be equipped with a feeder device. The Bilke unit is fed by a conveyor belt arrangement while the Peurala unit is equipped with a feeder roll. In addition, both machine types are equipped with a conveyor belt discharging device (e.g. for discharging split wood directly into a trailer). The Bilke unit can also be operated on extraction racks in the woods as the stems due to be split are fed into it from the side and the conveyor discharges the split wood rearwards into the trailer. The trailer can be hooked onto the splitting unit's draw-hook. At the landing, the Bilke unit was used to split a total of 14.2 m 3 and the Peurala unit 8.0 m 3 of approx. 3-metrelong stems averaging 9 cm in diameter. In addition to this, the Bilke unit was used to split ca. 17 m 3 of 3.5 metre-long stems with on average diameter of ca. 6 cm; the stems were in bunches alongside the extraction racks. The person operating the machines for the purposes of this study was a 27-year- old forest worker. The mean productivity achieved at the landing when using the Bilke unit was 7.7 m 3 while that of the Peurala unit was 5.8 m 3 per effective hour. When operated in the woods, the productivity achieved with the Bilke unit (excluding felling-cross cutting-delimbing-bunching and forest haulage work) was 2.8 m 3 /h. When applying a productivity of 1.7 m 3 for felling-cross cutting- delimbing-bunching work and 5.5. m 3 for forest haulage, the entire harvesting chain's productivity was 0.9 m 3 per effective hour

  15. The effect of space allowance and cage size on laying hens housed in furnished cages, Part II: Behavior at the feeder

    Science.gov (United States)

    Widowski, T. M; Caston, L. J; Casey-Trott, T. M; Hunniford, M. E

    2017-01-01

    Abstract Standards for feeder (a.k.a. feed trough) space allowance (SA) are based primarily on studies in conventional cages where laying hens tend to eat simultaneously, limiting feeder space. Large furnished cages (FC) offer more total space and opportunities to perform a greater variety of behaviors, which may affect feeding behavior and feeder space requirements. Our objective was to determine the effects of floor/feeder SA on behavior at the feeder. LSL-Lite hens were housed in FC equipped with a nest, perches, and a scratch mat. Hens with SA of either 520 cm2 (Low; 8.9 cm feeder space/hen) or 748 cm2 (High; 12.8 cm feeder space/hen) per bird resulted in groups of 40 vs. 28 birds in small FC (SFC) and 80 vs. 55 in large FC (LFC). Chain feeders ran at 0500, 0800, 1100, 1400, and 1700 with lights on at 0500 and off at 1900 hours. Digital recordings of FC were scanned at chain feeder onset and every 15 min for one h after (5 scans × 5 feeding times × 2 d) to count the number of birds with their head in the feeder. All occurrences of aggressive pecks and displacements during 2 continuous 30-minute observations at 0800 h and 1700 h also were counted. Mixed model repeated analyses tested the effects of SA, cage size, and time on the percent of hens feeding, and the frequency of aggressive pecks and displacements. Surprisingly, the percent of birds feeding simultaneously was similar regardless of cage size (LFC: 23.0 ± 0.9%; SFC: 24.0 ± 1.0%; P = 0.44) or SA (Low: 23.8 ± 0.9%; High: 23.3 ± 1.0%; P = 0.62). More birds were observed feeding at 1700 h (35.3 ± 0.1%) than any at other time (P < 0.001). Feeder use differed by cage area (nest, middle, or scratch) over the d (P < 0.001). The frequency of aggressive pecks was low overall and not affected by SA or cage size. Frequency of displacements was also low but greater at Low SA (P = 0.001). There was little evidence of feeder competition at the Low SA in this study. PMID:29050409

  16. Feeders of free-roaming cats: personal characteristics, feeding practices and data on cat health and welfare in an urban setting of Israel

    Directory of Open Access Journals (Sweden)

    Idit eGunther

    2016-03-01

    Full Text Available Cat feeders serve as an important source of available food for free-roaming cats (FRC and can play a central role in providing data on FRC distribution, welfare, and health. Data on cat feeder personalities as well as a better understanding of their feeding practices offer relevance for decision making concerning FRC population control strategies. The current study surveyed 222 FRC feeders who responded to a municipal trap-neuter-return (TNR campaign in an Israeli central urban setting. The aim of the study was to describe their personal characteristics, feeding practices and the FRC populations they feed. Feeders were divided into four groups according to the number of cats they claimed to feed per day (group 1: fed up to five cats; group 2: fed six to 10 cats; group 3: fed 11-20 cats; group 4: fed ≥21 cats. Most feeders were women (81%, with a median age of 58 years (range 18-81. The feeders reported an overall feeding of 3,337 cats in 342 different feeding locations. Feeders of group 4 comprised of 15.31% (n=34 of all feeders, but fed 56% (n=1869 of the FRC in 37.42% (n=128 of the feeding locations. 'Heavy' feeders (groups 3 and 4 reported that they traveled significantly longer distances in order to feed the cats. Commercial dry food consisted of 90% of the food they provided, with 66% of them feeding once a day, with less food per cat per day than the other feeder groups. Interestingly, 'heavy' feeders were usually singles, had on average fewer siblings, a clear preference for owning cats as pets and lived in lower income neighborhoods. According to the feeders' reports on the FRC populations they fed, 69.7% (2325/3337 cats were neutered and 11.8% (395/3337 were kittens. In addition, they reported that 1.6% (54/3337 of the cats were limping, 2% (67/3337 suffered from a systemic disease, 4% (135/3337 had skin lesions, and 3.9% (130/3337 were suffering from a chronic disability. Abundance of kittens and morbidity rate were significantly and

  17. The effect of space allowance and cage size on laying hens housed in furnished cages, Part II: Behavior at the feeder.

    Science.gov (United States)

    Widowski, T M; Caston, L J; Casey-Trott, T M; Hunniford, M E

    2017-09-01

    Standards for feeder (a.k.a. feed trough) space allowance (SA) are based primarily on studies in conventional cages where laying hens tend to eat simultaneously, limiting feeder space. Large furnished cages (FC) offer more total space and opportunities to perform a greater variety of behaviors, which may affect feeding behavior and feeder space requirements. Our objective was to determine the effects of floor/feeder SA on behavior at the feeder. LSL-Lite hens were housed in FC equipped with a nest, perches, and a scratch mat. Hens with SA of either 520 cm2 (Low; 8.9 cm feeder space/hen) or 748 cm2 (High; 12.8 cm feeder space/hen) per bird resulted in groups of 40 vs. 28 birds in small FC (SFC) and 80 vs. 55 in large FC (LFC). Chain feeders ran at 0500, 0800, 1100, 1400, and 1700 with lights on at 0500 and off at 1900 hours. Digital recordings of FC were scanned at chain feeder onset and every 15 min for one h after (5 scans × 5 feeding times × 2 d) to count the number of birds with their head in the feeder. All occurrences of aggressive pecks and displacements during 2 continuous 30-minute observations at 0800 h and 1700 h also were counted. Mixed model repeated analyses tested the effects of SA, cage size, and time on the percent of hens feeding, and the frequency of aggressive pecks and displacements. Surprisingly, the percent of birds feeding simultaneously was similar regardless of cage size (LFC: 23.0 ± 0.9%; SFC: 24.0 ± 1.0%; P = 0.44) or SA (Low: 23.8 ± 0.9%; High: 23.3 ± 1.0%; P = 0.62). More birds were observed feeding at 1700 h (35.3 ± 0.1%) than any at other time (P Feeder use differed by cage area (nest, middle, or scratch) over the d (P feeder competition at the Low SA in this study. © The Author 2017. Published by Oxford University Press on behalf of Poultry Science Association.

  18. Advanced feeder-free generation of induced pluripotent stem cells directly from blood cells.

    Science.gov (United States)

    Trokovic, Ras; Weltner, Jere; Nishimura, Ken; Ohtaka, Manami; Nakanishi, Mahito; Salomaa, Veikko; Jalanko, Anu; Otonkoski, Timo; Kyttälä, Aija

    2014-12-01

    Generation of validated human induced pluripotent stem cells (iPSCs) for biobanking is essential for exploring the full potential of iPSCs in disease modeling and drug discovery. Peripheral blood mononuclear cells (PBMCs) are attractive targets for reprogramming, because blood is collected by a routine clinical procedure and is a commonly stored material in biobanks. Generation of iPSCs from blood cells has previously been reported using integrative retroviruses, episomal Sendai viruses, and DNA plasmids. However, most of the published protocols require expansion and/or activation of a specific cell population from PBMCs. We have recently collected a PBMC cohort from the Finnish population containing more than 2,000 subjects. Here we report efficient generation of iPSCs directly from PBMCs in feeder-free conditions in approximately 2 weeks. The produced iPSC clones are pluripotent and transgene-free. Together, these properties make this novel method a powerful tool for large-scale reprogramming of PBMCs and for iPSC biobanking. ©AlphaMed Press.

  19. Comparisons of benthic filter feeder communities before and after a large-scale capital dredging program.

    Science.gov (United States)

    Abdul Wahab, Muhammad Azmi; Fromont, Jane; Gomez, Oliver; Fisher, Rebecca; Jones, Ross

    2017-09-15

    Changes in turbidity, sedimentation and light over a two year large scale capital dredging program at Onslow, northwestern Australia, were quantified to assess their effects on filter feeder communities, in particular sponges. Community functional morphological composition was quantified using towed video surveys, while dive surveys allowed for assessments of species composition and chlorophyll content. Onslow is relatively diverse recording 150 sponge species. The area was naturally turbid (1.1 mean P 80 NTU), with inshore sites recording 6.5× higher turbidity than offshore localities, likely influenced by the Ashburton River discharge. Turbidity and sedimentation increased by up to 146% and 240% through dredging respectively, with corresponding decreases in light levels. The effects of dredging was variable, and despite existing caveats (i.e. bleaching event and passing of a cyclone), the persistence of sponges and the absence of a pronounced response post-dredging suggest environmental filtering or passive adaptation acquired pre-dredging may have benefited these communities. Copyright © 2017. Published by Elsevier Ltd.

  20. Real-time modeling and simulation of distribution feeder and distributed resources

    Science.gov (United States)

    Singh, Pawan

    The analysis of the electrical system dates back to the days when analog network analyzers were used. With the advent of digital computers, many programs were written for power-flow and short circuit analysis for the improvement of the electrical system. Real-time computer simulations can answer many what-if scenarios in the existing or the proposed power system. In this thesis, the standard IEEE 13-Node distribution feeder is developed and validated on a real-time platform OPAL-RT. The concept and the challenges of the real-time simulation are studied and addressed. Distributed energy resources include some of the commonly used distributed generation and storage devices like diesel engine, solar photovoltaic array, and battery storage system are modeled and simulated on a real-time platform. A microgrid encompasses a portion of an electric power distribution which is located downstream of the distribution substation. Normally, the microgrid operates in paralleled mode with the grid; however, scheduled or forced isolation can take place. In such conditions, the microgrid must have the ability to operate stably and autonomously. The microgrid can operate in grid connected and islanded mode, both the operating modes are studied in the last chapter. Towards the end, a simple microgrid controller modeled and simulated on the real-time platform is developed for energy management and protection for the microgrid.

  1. Feasibility assessment of optical technologies for reliable high capacity feeder links

    Science.gov (United States)

    Witternigg, Norbert; Schönhuber, Michael; Leitgeb, Erich; Plank, Thomas

    2013-08-01

    Space telecom scenarios like data relay satellite and broadband/broadcast service providers require reliable feeder links with high bandwidth/data rate for the communication between ground station and satellite. Free space optical communication (FSOC) is an attractive alternative to microwave links, improving performance by offering abundant bandwidth at small apertures of the optical terminals. At the same time Near-Earth communication by FSOC avoids interference with other services and is free of regulatory issues. The drawback however is the impairment by the laser propagation through the atmosphere at optical wavelengths. Also to be considered are questions of eye safety for ground personnel and aviation. In this paper we assess the user requirements for typical space telecom scenarios and compare these requirements with solutions using optical data links through the atmosphere. We suggest a site diversity scheme with a number of ground stations and a switching scheme using two optical terminals on-board the satellite. Considering the technology trade-offs between four different optical wavelengths we recommend the future use of 1.5 μm laser technology and calculate a link budget for an atmospheric condition of light haze on the optical path. By comparing link budgets we show an outlook to the future potential use of 10 μm laser technology.

  2. Controlling Voltage Levels of Distribution Network-Radial Feeder after Connecting Wind Turbines to the Network

    Directory of Open Access Journals (Sweden)

    Muhammad Al Badri

    2017-11-01

    Full Text Available Several factors in power generation and supply need to be taken into account such as shortages of energy supply, system stability, and energy quality and system disruption due to network losses, industrial development and population expansion. The addition of wind turbines to the distribution network is of great benefit in providing additional power and solving these problems, but this addition is accompanied by the problem of low voltage network. This research found optimal solutions to the problem of low voltage distribution network after connecting wind turbines. The main idea of this paper is to optimize the low-voltage problem as a result of connecting the wind turbines to the "far end" of the radial feeder for a distribution network and to obtain a voltage level within an acceptable and stable range. The problem of low voltage solved by using the load-drop compensation, capacitor-bank and “doubly-fed” induction generators. The results of this study were based on the operation of the entire design of the simulation system which would be compatible with the reality of the energy flow of all network components by using the PSCAD program. The present analysis program revealed an optimum solution for the low voltage profile of the distribution network after connecting the wind turbine.

  3. Utilisation of symmetrical components in a communication-based protection for loop MV feeders with variable short-circuit power

    DEFF Research Database (Denmark)

    Ciontea, Catalin-Iosif; Bak, Claus Leth; Blaabjerg, Frede

    2018-01-01

    -circuit power is presented. It relies on utilisation of symmetrical components of the short-circuit currents and on communication between the protection relays. The proposed method addresses the Single Phase to Ground (SPG) faults occurring in directly grounded distribution networks, with focus on closed......Variability of the available short-circuit power also implies variation of the fault level, which can potentially cause several protection problems in the electric networks. In this paper, a novel protection method that is insensitive to the fault level changes caused by variable short......-loop Medium Voltage (MV) feeders. Case studies are presented, which demonstrate that the proposed protection scheme is capable of effectively detecting the SPG faults in closed-loop feeders with variable short-circuit power....

  4. A Double-Resistive Active Power Filter System to Attenuate Harmonic Voltages of a Radial Power Distribution Feeder

    DEFF Research Database (Denmark)

    Sun, Xiaofeng; Han, Ruijing; Shen, Hong

    2016-01-01

    voltages. This paper proposes a double-resistive active power filter (D-RAPF) system consisting of a terminal-RAPF and an attenuation-RAPF for each individual harmonic. The terminal-RAPF operating as the characteristic impedance of the feeder is installed at the end bus to suppress harmonic propagation......Harmonic propagation between power-factor correction capacitors and system inductors seriously deteriorates power quality in a radial power distribution feeder. Installation of a resistive active power filter (RAPF) at the end bus only suppresses harmonic propagation, not attenuates harmonic...... at all harmonic frequencies. The attenuation-RAPF, whose control gain can be set according to the requirements of the harmonic voltage distortion limit, is installed at a specific position for each individual harmonic to attenuate the corresponding harmonic voltages. The D-RAPF system not only suppresses...

  5. Derivation and characterization of the NIH registry human stem cell line NYSCF100 line under defined feeder-free conditions

    Directory of Open Access Journals (Sweden)

    Ana Sevilla

    2018-05-01

    Full Text Available The human embryonic stem cell line NYSCFe001-A was derived from a day 6 blastocyst in feeder-free and antibiotic free conditions. The blastocyst was voluntarily donated for research as surplus after in vitro fertilization treatment following informed consent. The NYSCFe001-A line, registered as NYSCF100 on the NIH registry, presents normal karyotype, is mycoplasma free, expresses all the pluripotency markers and has the potential to differentiate into all three germ layers in vitro.

  6. Effects of Home Energy Management Systems on Distribution Utilities and Feeders Under Various Market Structure; NREL (National Renewable Energy Laboratory)

    Energy Technology Data Exchange (ETDEWEB)

    Ruth, M.; Pratt, A.; Lunacek, M.; Mittal, S.; Wu, H.; Jones, W.

    2015-06-15

    The combination of distributed energy resources (DER) and retail tariff structures to provide benefits to both utility consumers and the utilities is not well understood. To improve understanding, an Integrated Energy System Model (IESM) is being developed to simulate the physical and economic aspects of DER technologies, the buildings where they reside, and feeders servicing them. The IESM was used to simulate 20 houses with home energy management systems on a single feeder under a time-of-use (TOU) tariff to estimate economic and physical impacts on both the households and the distribution utilities. Home energy management systems (HEMS) reduce consumers’ electric bills by precooling houses in the hours before peak electricity pricing. Utilization of HEMS reduce peak loads during high price hours but shifts it to hours with off-peak and shoulder prices, resulting in a higher peak load. used to simulate 20 houses with home energy management systems on a single feeder under a time-of-use (TOU) tariff to estimate economic and physical impacts on both the households and the distribution utilities. Home energy management systems (HEMS) reduce consumers’ electric bills by precooling houses in the hours before peak electricity pricing. Utilization of HEMS reduce peak loads during high price hours but shifts it to hours with off-peak and shoulder prices, resulting in a higher peak load.

  7. Differences in carotenoid accumulation among three feeder-cricket species: implications for carotenoid delivery to captive insectivores.

    Science.gov (United States)

    Ogilvy, Victoria; Fidgett, Andrea L; Preziosi, Richard F

    2012-01-01

    There are a limited number of feeder-invertebrates available to feed captive insectivores, and many are deficient in certain nutrients. Gut-loading is used to increase the diversity of nutrients present in the captive insectivore diet; however, little is known about delivery of carotenoids via gut-loading. Carotenoids may influence health and reproduction due to their roles in immune and antioxidant systems. We assessed interspecific variation in carotenoid accumulation and retention in three feeder-cricket species (Gryllus bimaculatus, Gryllodes sigillatus and Acheta domesticus) fed one of three diets (wheat-bran, fish-food based formulated diet, and fresh fruit and vegetables). Out of the three species of feeder-cricket in the fish-food-based dietary treatment group, G. bimaculatus had the greatest total carotenoid concentration. All cricket species fed the wheat-bran diet had very low carotenoid concentrations. Species on the fish-food-based diet had intermediate carotenoid concentrations, and those on the fruit and vegetable diet had the highest concentrations. Carotenoid retention was poor across all species. Overall, this study shows that, by providing captive insectivores with G. bimaculatus crickets recently fed a carotenoid-rich diet, the quantity of carotenoids in the diet can be increased. © 2011 Wiley Periodicals, Inc.

  8. Cool Down Experiences with the SST-1 Helium Cryogenics System before and after Current Feeders System Modification

    Science.gov (United States)

    Patel, R.; Panchal, P.; Panchal, R.; Tank, J.; Mahesuriya, G.; Sonara, D.; Srikanth, G. L. N.; Garg, A.; Bairagi, N.; Christian, D.; Patel, K.; Shah, P.; Nimavat, H.; Sharma, R.; Patel, J. C.; Gupta, N. C.; Prasad, U.; Sharma, A. N.; Tanna, V. L.; Pradhan, S.

    The SST-1 machine comprises a superconducting magnet system (SCMS), which includes TF and PF magnets. In order to charge the SCMS, we need superconducting current feeders consisting of SC feeders and vapor cooled current leads (VCCLs). We have installed all 10 (+/-) pairs of VCCLs for the TF and PF systems. While conducting initial engineering validation of the SST-1 machine, our prime objective was to produce circular plasma using only the TF system. During the SST-1 campaign I to VI, we have to stop the PF magnets cooling in order to get the cryo- stable conditions for current charging of the TF magnets system. In that case, the cooling of the PF current leads is not essential. It has been also observed that after aborting the PF system cooling, there was a limited experimental window of TF operation. Therefore, in the recent SST-1 campaign-VII, we removed the PF current leads (9 pairs) and kept only single (+/-) pair of the 10,000 A rated VCCLs to realize the charging of the TF system for the extended window of operation. We have observed a better cryogenic stability in the TF magnets after modifications in the CFS. In this paper, we report the comparison of the cool down performance for the SST-1 machine operation before and after modifications of the current feeders system.

  9. Busbar arcs at large fusion magnets: Conductor to feeder tube arcing model experiments with the LONGARC device

    Energy Technology Data Exchange (ETDEWEB)

    Klimenko, Dmitry, E-mail: dmitry.klimenko@kit.edu; Pasler, Volker

    2014-10-15

    Highlights: •The LONGARC device was successfully implemented for busbar to feeder tubes arcing model experiments. •Arcing at an ITER busbar inside its feeder tube was simulated in scaled model experiments. •The narrower half tubes imply a slight increase of the arc propagation speed in compare to full tube experiments. •All simulated half tubes experiments show severe damage indicating that the ITER inner feeder tube will not withstand a busbar arc. -- Abstract: Electric arcs moving along the power cables (the so-called busbars) of the toroidal field (TF) coils of ITER may reach and penetrate the cryostat wall. Model experiments with the new LONGARC device continue the VACARC (VACuum ARC) experiments that were initiated to investigate the propagation and destruction mechanisms of busbar arcs in small scale [1]. The experiments are intended to support the development and validation of a numerical model. LONGARC overcomes the space limitations inside VACARC and allows also for advanced 1:3 (vs. ITER full scale) model setups. The LONGARC device and first results are presented below.

  10. Water quality in Pearl Harbor and feeder streams during 1971 - 2001 collected primarily by oceanography students from Leeward Community College (NODC Accession 0000590)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Water quality data were collected in Pearl Harbor and surrounding feeder streams from 30 December 1971 to 24 August 2001. Data were collected by Leeward Community...

  11. Feeder Voltage Regulation with High-Penetration PV Using Advanced Inverters and a Distribution Management System: A Duke Energy Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Palmintier, Bryan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Giraldez, Julieta [National Renewable Energy Lab. (NREL), Golden, CO (United States); Gruchalla, Kenny [National Renewable Energy Lab. (NREL), Golden, CO (United States); Gotseff, Peter [National Renewable Energy Lab. (NREL), Golden, CO (United States); Nagarajan, Adarsh [National Renewable Energy Lab. (NREL), Golden, CO (United States); Harris, Tom [National Renewable Energy Lab. (NREL), Golden, CO (United States); Bugbee, Bruce [National Renewable Energy Lab. (NREL), Golden, CO (United States); Baggu, Murali [National Renewable Energy Lab. (NREL), Golden, CO (United States); Gantz, Jesse [GE Grid Solutions, Fairfield, CT (United States); Boardman, Ethan [GE Grid Solutions, Fairfield, CT (United States)

    2016-11-01

    Duke Energy, Alstom Grid, and the National Renewable Energy Laboratory teamed up to better understand the impacts of solar photovoltaics (PV) on distribution system operations. The core goal of the project is to compare the operational - specifically, voltage regulation - impacts of three classes of PV inverter operations: 1.) Active power only (Baseline); 2.) Local inverter control (e.g., PF...not equal...1, Q(V), etc.); and 3.) Integrated volt-VAR control (centralized through the distribution management system). These comparisons were made using multiple approaches, each of which represents an important research-and-development effort on its own: a) Quasi-steady-state time-series modeling for approximately 1 year of operations using the Alstom eTerra (DOTS) system as a simulation engine, augmented by Python scripting for scenario and time-series control and using external models for an advanced inverter; b) Power-hardware-in-the-loop (PHIL) testing of a 500-kVA-class advanced inverter and traditional voltage regulating equipment. This PHIL testing used cosimulation to link full-scale feeder simulation using DOTS in real time to hardware testing; c) Advanced visualization to provide improved insights into time-series results and other PV operational impacts; and d) Cost-benefit analysis to compare the financial and business-model impacts of each integration approach.

  12. Changes in food intake and abnormal behavior using a puzzle feeder in newly acquired sub-adult rhesus monkeys (Macaca mulatta): a short term study.

    Science.gov (United States)

    Lee, Jae-Il; Lee, Chi-Woo; Kwon, Hyouk-Sang; Kim, Young-Tae; Park, Chung-Gyu; Kim, Sang-Joon; Kang, Byeong-Cheol

    2008-10-01

    The majority of newly acquired nonhuman primates encounter serious problems adapting themselves to new environments or facilities. In particular, loss of appetite and abnormal behavior can occur in response to environmental stresses. These adaptation abnormalities can ultimately have an affect on the animal's growth and well-being. In this study, we evaluated the affects of a puzzle feeder on the food intake and abnormal behavior of newly acquired rhesus monkeys for a short period. The puzzle feeder was applied to 47- to 58-month-old animals that had never previously encountered one. We found that there was no difference in the change of food intake between the bucket condition and the puzzle feeder condition. In contrast, the time spent for consumption of food was three times longer in the puzzle feeder condition than in the bucket condition. Two monkeys initially exhibited stereotypic behavior. One showed a decreasing, and the other an increasing pattern of abnormal behavior after introduction of the puzzle feeder. In conclusion, this result suggests that over a short period, the puzzle feeder can only affect the time for food consumption since it failed to affect the food intake and did not consistently influence stereotypic behaviors in newly acquired rhesus monkeys.

  13. Adjusting the weaning age of calves fed by automated feeders according to individual intakes of solid feed.

    Science.gov (United States)

    de Passillé, A M; Rushen, J

    2012-09-01

    When weaned at the ages typical of commercial dairy production, dairy calves usually show reduced growth rates, lowered energy intake, and increased behavioral signs of hunger, reflecting their difficulty in switching from a milk diet to solid feed. However, large differences exist between calves in their ability to adapt to solid feed, and automated feeders allow the age of weaning to be adjusted to an individual calf's intake of solid feed. We examined the effects of weaning according to solid feed intake on age at weaning, feed intake, and behavioral signs of hunger. In a 2×2 factorial design, 60 female Holstein calves in groups of 8 and fed milk, grain starter, and hay from automated feeders began to be weaned when their voluntary intake of grain starter was either 400 g/d (high start) or 200 g/d (low start), with weaning completed when their voluntary intakes of starter were either 1,600 g/d (high end) or 800 g/d (low end). Digestible energy intakes were calculated from milk, starter and hay intakes, corrected for body weights, calves were weighed, and the frequency of visits to the milk feeders were measured each day. The main effects and interactions between treatments were tested with ANOVA. Large differences were observed between calves in the age at which weaning was complete, with weaning completed earlier for low-end calves compared with high-end calves. No treatment effects (either of start amount or end amount) on intakes of milk, starter, or hay or on weight gains occurred. However, the calves that began weaning earlier had longer durations of weaning, greater growth rates from d 20 to 87, and were heavier on d 87, and had lower milk intakes, higher starter intakes, higher hay intakes, and a greater digestible energy intake, but showed more unrewarded visits to the milk feeder. Adjusting the age at which individual calves are weaned off milk according to their ability to eat solid feed can reduce the age at which weaning occurs while reducing the

  14. Investigating DRG cost weights for hospitals in middle income countries.

    Science.gov (United States)

    Ghaffari, Shahram; Doran, Christopher; Wilson, Andrew; Aisbett, Chris; Jackson, Terri

    2009-01-01

    Identifying the cost of hospital outputs, particularly acute inpatients measured by Diagnosis Related Groups (DRGs), is an important component of casemix implementation. Measuring the relative costliness of specific DRGs is useful for a wide range of policy and planning applications. Estimating the relative use of resources per DRG can be done through different costing approaches depending on availability of information and time and budget. This study aims to guide costing efforts in Iran and other countries in the region that are pursuing casemix funding, through identifying the main issues facing cost finding approaches and introducing the costing models compatible with their hospitals accounting and management structures. The results show that inadequate financial and utilisation information at the patient's level, poorly computerized 'feeder systems'; and low quality data make it impossible to estimate reliable DRGs costs through clinical costing. A cost modelling approach estimates the average cost of 2.723 million Rials (Iranian Currency) per DRG. Using standard linear regression, a coefficient of 0.14 (CI = 0.12-0.16) suggests that the average cost weight increases by 14% for every one-day increase in average length of stay (LOS).We concluded that calculation of DRG cost weights (CWs) using Australian service weights provides a sensible starting place for DRG-based hospital management; but restructuring hospital accounting systems, designing computerized feeder systems, using appropriate software, and development of national service weights that reflect local practice patterns will enhance the accuracy of DRG CWs.

  15. The filter feeder Dreissena polymorpha affects nutrient, silicon, and metal(loid) mobilization from freshwater sediments.

    Science.gov (United States)

    Schaller, Jörg; Planer-Friedrich, Britta

    2017-05-01

    Organic sediments in aquatic ecosystems are well known sinks for nutrients, silicon, and metal(loid)s. Organic matter-consuming organisms like invertebrate shredders, grazers, and bioturbators significantly affect element fixation or remobilization by changing redox conditions or binding properties of organic sediments. Little is known about the effect of filter feeders, like the zebra mussel Dreissena polymorpha, an invasive organism in North American and European freshwater ecosystems. A laboratory batch experiment exposing D. polymorpha (∼1200 organisms per m 2 ) to organic sediment from a site contaminated with arsenic, copper, lead, and uranium revealed a significant uptake and accumulation of arsenic, copper, iron, and especially uranium both into the soft body tissues and the seashell. This is in line with previous observations of metal(loid) accumulation from biomonitoring studies. Regarding its environmental impact, D. polymorpha significantly contributed to mobilization of silicon, iron, phosphorus, arsenic, and copper and to immobilization of uranium (p < 0.001), probably driven by redox conditions, microbial activity within the gut system, or active control of element homeostasis. No net mobilization or immobilization was observed for zinc and lead, because of their low mobility at the prevailing pH of 7.5-8.5. The present results suggest that D. polymorpha can both ameliorate (nutrient mobilization, immobilization of toxicants mobile under oxic conditions) or aggravate negative effects (mobilization of toxicants mobile under reducing conditions) in ecosystems. Relating the results of the present study to observed population densities in natural freshwater ecosystems suggests a significant influence of D. polymorpha on element cycling and needs to be considered in future studies. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Uptake, accumulation, and biotransformation of metal oxide nanoparticles by a marine suspension-feeder

    International Nuclear Information System (INIS)

    Montes, Milka O.; Hanna, Shannon K.; Lenihan, Hunter S.; Keller, Arturo A.

    2012-01-01

    Highlights: ► Suspension-feeding by mussels can greatly alter mobility and fate of metal oxide nanoparticles. ► Bioprocessing of metal oxide nanoparticles by mussels removes large fraction from water column. ► Mussels repackage metal oxide nanoparticles in highly concentrated pseudofeces. ► Novel biological pathway between major compartments in marine systems. ► Very different outcome for ZnO and CeO 2 nanoparticles based on their solubility. - Abstract: A growing body of evidence indicates that some engineered nanoparticles (ENPs) are toxic to organisms that perform important ecosystem services in terrestrial and aquatic ecosystems. However, toxicity can be influenced by the biotransformation of contaminants, including ENPs, as it may alter the fate and transport of these substances. In turn, fate and transport can influence their bioavailability. To understand how biotransformation influences the fate and transport of ENPs in marine ecosystems, we exposed suspension-feeding mussels, Mytilus galloprovincialis, to two common nano-metal oxides, CeO 2 and ZnO, over a range of concentrations from 1 mg L −1 to 10 mg L −1 , in a laboratory experiment. Mussels exposed to 10 mg L −1 accumulated 62 μg g −1 of Ce and 880 μg g −1 of Zn on a dry tissue basis but rejected 21,000 μg g −1 for Ce and 63,000 μg g −1 for Zn in pseudofeces. Scanning electron microscope evidence indicates CeO 2 remained as ENPs but ZnO did not after being rejected by the mussels. Mussels filtered most of the CeO 2 from the aqueous media, while a significant fraction of Zn remained in solution. Differences in ENP solubility affect ENP uptake, excretion, and accumulation in mussels. Our study highlights the potential role of marine suspension feeders in biotransformation of ENPs.

  17. Does proximity to urban centres affect the dietary regime of marine benthic filter feeders?

    Science.gov (United States)

    Puccinelli, Eleonora; Noyon, Margaux; McQuaid, Christopher D.

    2016-02-01

    Threats to marine ecosystems include habitat destruction and degradation of water quality, resulting from land- and ocean-based human activities. Anthropogenic input causing modification of water quality, can affect primary productivity and thus food availability and quality for higher trophic levels. This is especially important for sedentary benthic intertidal communities, which rely on local food availability. We investigated the effect of urbanization on the dietary regime of four species of intertidal filter feeders (three barnacles and one mussel) at sites close to high-density cities and at sites far from heavily urbanized areas using fatty acid and stable isotope techniques. δ15N was significantly higher at urbanized sites compared to their corresponding control sites for all species with few exceptions, while no effect on δ13C was recorded. Barnacle fatty acid profiles were not affected by cities, while mussels from sites close to cities had fatty acid signatures with a higher proportion of polyunsaturated fatty acids (PUFA). We suggest that the enrichment in δ15N at urbanised sites reflects the influence of anthropogenically derived nitrogen directly linked to wastewater input from domestic and industrial sewage. Linked to this, the high proportion of PUFA in mussels at urbanized sites may reflect the influence of increased nitrogen concentrations on primary production and enhanced growth of large phytoplankton cells. The results indicate that anthropogenic effects can strongly influence the diets of benthic organisms, but these effects differ among taxa. Changes in the diet of such habitat forming species can affect their fitness and survival with potential effects on the populations associated with them.

  18. A new stalked filter-feeder from the middle Cambrian Burgess Shale, British Columbia, Canada.

    Directory of Open Access Journals (Sweden)

    Lorna J O'Brien

    Full Text Available Burgess Shale-type deposits provide invaluable insights into the early evolution of body plans and the ecological structure of Cambrian communities, but a number of species, continue to defy phylogenetic interpretations. Here we extend this list to include a new soft-bodied animal, Siphusauctum gregarium n. gen. and n. sp., from the Tulip Beds (Campsite Cliff Shale Member, Burgess Shale Formation of Mount Stephen (Yoho National Park, British Columbia. With 1,133 specimens collected, S. gregarium is clearly the most abundant animal from this locality.This stalked animal (reaching at least 20 cm in length, has a large ovoid calyx connected to a narrow bilayered stem and a small flattened or bulb-like holdfast. The calyx is enclosed by a flexible sheath with six small openings at the base, and a central terminal anus near the top encircled by indistinct openings. A prominent organ, represented by six radially symmetrical segments with comb-like elements, surrounds an internal body cavity with a large stomach, conical median gut and straight intestine. Siphusauctum gregarium was probably an active filter-feeder, with water passing through the calyx openings, capturing food particles with its comb-like elements. It often occurs in large assemblages on single bedding planes suggesting a gregarious lifestyle, with the animal living in high tier clusters. These were probably buried en masse more or less in-situ by rapid mud flow events.Siphusauctum gregarium resembles Dinomischus, another Cambrian enigmatic stalked animal. Principal points of comparison include a long stem with a calyx containing a visceral mass and bract-like elements, and a similar lifestyle albeit occupying different tiering levels. The presence in both animals of a digestive tract with a potential stomach and anus suggest a grade of organization within bilaterians, but relationships with extant phyla are not straightforward. Thus, the broader affinities of S. gregarium remain

  19. Effect of concentrate feeder design on performance, eating and animal behavior, welfare, ruminal health, and carcass quality in Holstein bulls fed high-concentrate diets.

    Science.gov (United States)

    Verdú, M; Bach, A; Devant, M

    2015-06-01

    A total of 240 Holstein bulls (121 ± 2.0 kg initial BW; 99 ± 1.0 d of age), from 2 consecutive fattening cycles, were randomly allocated in 1 of 6 pens and assigned to 1 of the 3 treatments consisting of different concentrate feeder designs: a control feeder with 4 feeding spaces (CF), a feeder with less concentrate capacity (CFL), and a single-space feeder with lateral protections (SF). Each pen had a straw feeder and a drinker. All animals were fed a high-concentrate diet for ad libitum intake. Concentrate consumption was recorded daily using a computerized feeder, straw consumption was recorded weekly, and BW was recorded every 14 d. Animal behavior was registered on d 1, 3, 5, 8, and 14 and every 28 d by scan sampling. Eating behavior at concentrate feeders was filmed on d 12, 125, and 206. On d 7, 120, and 204, samples of rumen contents were collected for measurement of pH and VFA and blood samples were obtained to analyze NEFA, haptoglobin, glucose, and insulin. Animals were slaughtered after 223 d, and HCW and lesions of the rumen wall and liver were recorded. The accumulative concentrate consumption per animal tended (P = 0.09) to be greater with CF than with CFL and SF. Also, CV of concentrate consumption was greater (P carcass data. Also, no differences among treatments in rumen wall evaluation and liver abscesses were observed. At 7 and 204 d of study, SF bulls had greater (P animal welfare in Holstein bulls fed high-concentrate diets. However, at the beginning, there was evidence that animals fed using SF had problems with adaptation.

  20. Uptake, accumulation, and biotransformation of metal oxide nanoparticles by a marine suspension-feeder

    Energy Technology Data Exchange (ETDEWEB)

    Montes, Milka O. [University of California Center for Environmental Implications of Nanotechnology, Bren School of Environmental Science and Management, University of California, Santa Barbara, CA 93106 (United States); University of Texas of the Permian Basin, 4901 E. University, Odessa, TX 79762 (United States); Hanna, Shannon K.; Lenihan, Hunter S. [University of California Center for Environmental Implications of Nanotechnology, Bren School of Environmental Science and Management, University of California, Santa Barbara, CA 93106 (United States); Keller, Arturo A., E-mail: keller@bren.ucsb.edu [University of California Center for Environmental Implications of Nanotechnology, Bren School of Environmental Science and Management, University of California, Santa Barbara, CA 93106 (United States)

    2012-07-30

    Highlights: Black-Right-Pointing-Pointer Suspension-feeding by mussels can greatly alter mobility and fate of metal oxide nanoparticles. Black-Right-Pointing-Pointer Bioprocessing of metal oxide nanoparticles by mussels removes large fraction from water column. Black-Right-Pointing-Pointer Mussels repackage metal oxide nanoparticles in highly concentrated pseudofeces. Black-Right-Pointing-Pointer Novel biological pathway between major compartments in marine systems. Black-Right-Pointing-Pointer Very different outcome for ZnO and CeO{sub 2} nanoparticles based on their solubility. - Abstract: A growing body of evidence indicates that some engineered nanoparticles (ENPs) are toxic to organisms that perform important ecosystem services in terrestrial and aquatic ecosystems. However, toxicity can be influenced by the biotransformation of contaminants, including ENPs, as it may alter the fate and transport of these substances. In turn, fate and transport can influence their bioavailability. To understand how biotransformation influences the fate and transport of ENPs in marine ecosystems, we exposed suspension-feeding mussels, Mytilus galloprovincialis, to two common nano-metal oxides, CeO{sub 2} and ZnO, over a range of concentrations from 1 mg L{sup -1} to 10 mg L{sup -1}, in a laboratory experiment. Mussels exposed to 10 mg L{sup -1} accumulated 62 {mu}g g{sup -1} of Ce and 880 {mu}g g{sup -1} of Zn on a dry tissue basis but rejected 21,000 {mu}g g{sup -1} for Ce and 63,000 {mu}g g{sup -1} for Zn in pseudofeces. Scanning electron microscope evidence indicates CeO{sub 2} remained as ENPs but ZnO did not after being rejected by the mussels. Mussels filtered most of the CeO{sub 2} from the aqueous media, while a significant fraction of Zn remained in solution. Differences in ENP solubility affect ENP uptake, excretion, and accumulation in mussels. Our study highlights the potential role of marine suspension feeders in biotransformation of ENPs.

  1. Lake Bacterial Assemblage Composition Is Sensitive to Biological Disturbance Caused by an Invasive Filter Feeder.

    Science.gov (United States)

    Denef, Vincent J; Carrick, Hunter J; Cavaletto, Joann; Chiang, Edna; Johengen, Thomas H; Vanderploeg, Henry A

    2017-01-01

    One approach to improve forecasts of how global change will affect ecosystem processes is to better understand how anthropogenic disturbances alter bacterial assemblages that drive biogeochemical cycles. Species invasions are important contributors to global change, but their impacts on bacterial community ecology are rarely investigated. Here, we studied direct impacts of invasive dreissenid mussels (IDMs), one of many invasive filter feeders, on freshwater lake bacterioplankton. We demonstrated that direct effects of IDMs reduced bacterial abundance and altered assemblage composition by preferentially removing larger and particle-associated bacteria. While this increased the relative abundances of many free-living bacterial taxa, some were susceptible to filter feeding, in line with efficient removal of phytoplankton cells of <2 μm. This selective removal of particle-associated and larger bacteria by IDMs altered inferred bacterial functional group representation, defined by carbon and energy source utilization. Specifically, we inferred an increased relative abundance of chemoorganoheterotrophs predicted to be capable of rhodopsin-dependent energy generation. In contrast to the few previous studies that have focused on the longer-term combined direct and indirect effects of IDMs on bacterioplankton, our study showed that IDMs act directly as a biological disturbance to which freshwater bacterial assemblages are sensitive. The negative impacts on particle-associated bacteria, which have been shown to be more active than free-living bacteria, and the inferred shifts in functional group representation raise the possibility that IDMs may directly alter bacterially mediated ecosystem functions. IMPORTANCE Freshwater bacteria play fundamental roles in global elemental cycling and are an intrinsic part of local food webs. Human activities are altering freshwater environments, and much has been learned regarding the sensitivity of bacterial assemblages to a variety of

  2. A new hybrid evolutionary algorithm based on new fuzzy adaptive PSO and NM algorithms for Distribution Feeder Reconfiguration

    International Nuclear Information System (INIS)

    Niknam, Taher; Azadfarsani, Ehsan; Jabbari, Masoud

    2012-01-01

    Highlights: ► Network reconfiguration is a very important way to save the electrical energy. ► This paper proposes a new algorithm to solve the DFR. ► The algorithm combines NFAPSO with NM. ► The proposed algorithm is tested on two distribution test feeders. - Abstract: Network reconfiguration for loss reduction in distribution system is a very important way to save the electrical energy. This paper proposes a new hybrid evolutionary algorithm to solve the Distribution Feeder Reconfiguration problem (DFR). The algorithm is based on combination of a New Fuzzy Adaptive Particle Swarm Optimization (NFAPSO) and Nelder–Mead simplex search method (NM) called NFAPSO–NM. In the proposed algorithm, a new fuzzy adaptive particle swarm optimization includes two parts. The first part is Fuzzy Adaptive Binary Particle Swarm Optimization (FABPSO) that determines the status of tie switches (open or close) and second part is Fuzzy Adaptive Discrete Particle Swarm Optimization (FADPSO) that determines the sectionalizing switch number. In other side, due to the results of binary PSO(BPSO) and discrete PSO(DPSO) algorithms highly depends on the values of their parameters such as the inertia weight and learning factors, a fuzzy system is employed to adaptively adjust the parameters during the search process. Moreover, the Nelder–Mead simplex search method is combined with the NFAPSO algorithm to improve its performance. Finally, the proposed algorithm is tested on two distribution test feeders. The results of simulation show that the proposed method is very powerful and guarantees to obtain the global optimization.

  3. Index-Based Assessment of Voltage Rise and Reverse Power Flow Phenomena in a Distribution Feeder Under High PV Penetration

    DEFF Research Database (Denmark)

    Hasheminamin, Maryam; Agelidis, Vassilios G.; Salehi, Vahid

    2015-01-01

    -based methodology for assessing the impact of high solar PV generation, considering the reverse power flow and voltage rise phenomena. Indices are defined that link these two phenomena and their impact on the voltage profile across the feeder. This assessment relies on detailed modeling of the network and the solar......The proliferation of photovoltaic (PV) generation in low- and medium-voltage distribution networks is expected to continue. Qualified studies can quantify adverse impacts of high PV penetration on distribution networks and assist utilities in decision making. This paper proposes an index...

  4. Overview of improvements in work practices and instrumentation for CANDU primary heat transport feeders in-service inspections

    Energy Technology Data Exchange (ETDEWEB)

    Marcotte, O., E-mail: olivier@nucleom.ca [Nucleom Inc., Quebec, Quebec (Canada); Rousseau, G., E-mail: rousseau.gilles.a@hydro.qc.ca [Hydro Quebec, Becancour, Quebec (Canada); Rochefort, E., E-mail: erochfort@zetec.com [Zetec Canada, Quebec, Quebec (Canada)

    2013-01-15

    The Canadian nuclear industry has developed many advanced non-destructive inspection techniques to be applied safely in hazardous environments in recent years. Automated systems, manual tooling and specialized software modules have been designed since early 2000s to provide complete and very efficient fitness for service inspection of primary heat transport system carbon steel feeder pipes. These techniques deal with complex geometries, difficult access and, radioactive environment. Complementary NDE techniques, namely Ultrasounds, eddy current, phased-array UT and automated scanners are used. This presentation describes the improvements in inspection practices and the advanced data analysis features. (author)

  5. Immunoflourescence and mRNA analysis of human embryonic stem cells (hESCs) grown under feeder-free conditions

    DEFF Research Database (Denmark)

    Awan, Aashir; Oliveri, Roberto S; Jensen, Pernille L

    2010-01-01

    onto 16-well glass chambers, and continuing with the general IF and qPCR steps will be provided. The techniques will be illustrated with new results on cellular localization of transcriptional factors and components of the Hedgehog, Wnt, and PDGF signaling pathways to primary cilia in stem cell......This chapter describes the procedures in order to do immunofluorescence (IF) microscopy and quantitative PCR (qPCR) analysis of human embryonic stem cells (hESCs) grown specifically under feeder-free conditions. A detailed protocol outlining the steps from initially growing the cells, passaging...

  6. Implementation of the resonant vibratory feeders control algorithm on Simatic S7-1200 from MATLAB Simulink enviroment

    Directory of Open Access Journals (Sweden)

    Mitrović Radomir B.

    2016-01-01

    Full Text Available Simulink is an important tool for modeling and simulation of process and control algorithms. It's expansion, PLC Coder, enables direct conversion of model subsystem into SCL, structured text code, which is then used by PLC IDE to create function blocks. This shortens developing time of algorithms for PLC controller. Also, this reduces possibility for a coding error. This paper describes Simulink PLC Coder and workflow for developing PID control algorithm for Siemens Simatic S7-1200 PLC. Control object used here is resonant vibratory feeder having electromagnetic drive.

  7. Using Human Gestures and Generic Skills to Instruct a Mobile Robot Arm in a Feeder Filling Scenario

    DEFF Research Database (Denmark)

    Pedersen, Mikkel Rath; Høilund, Carsten; Krüger, Volker

    2012-01-01

    Mobile robots that have the ability to cooperate with humans are able to provide new possibilities to manufac- turing industries. In this paper, we discuss our mobile robot arm that a) can provide assistance at different locations in a factory and b) that can be programmed using complex human...... actions such as pointing in Take this object. In this paper, we discuss the use of the mobile robot for a feeding scenario where a human operator specifies the parts and the feeders through pointing gestures. The system is partially built using generic robotic skills. Through extensive experiments, we...

  8. Introducing tool-based feeders to zoo-housed chimpanzees as a cognitive challenge: spontaneous acquisition of new types of tool use and effects on behaviours and use of space.

    OpenAIRE

    Yamanashi, Yumi; Matsunaga, Masayuki; Shimada, Kanae; Kado, Ryuichiro; Tanaka, Masayuki

    2016-01-01

    Cognitively challenging environments are vital to the welfare of captive animals. However, practical enrichment devices that can facilitate animals’ natural behaviours and accommodate individual variation are still limited. We created two types of feeders to facilitate tool-using behaviour in captive chimpanzees: pounding and dipping feeders. The pounding feeder was inspired by pestle-pounding behaviour observed in wild chimpanzees, and we expected that chimpanzees would pound soft foods. The...

  9. Evaluation of the effect of radiation levels and dose rates in irradiation of murine fibroblasts used as a feeder layer in the culture of human keratinocytes

    International Nuclear Information System (INIS)

    Yoshito, Daniele; Almeida, Tiago L.; Santin, Stefany Plumeri; Somessari, Elizabeth S.R.; Silveira, Carlos G. da; Mathor, Monica B.; Altran, Silvana C.; Isaac, Cesar

    2009-01-01

    In 1975, Rheinwald and Green published an effective methodology for obtaining and cultivating human keratinocytes. This methodology consisted of seeding keratinocytes onto a feeder layer composed of lineage 3T3 murine fibroblasts, the proliferation rate of which is then controlled through the action of ionizing radiation. The presence of the feeder layer encourages the development of keratinocyte colonies and their propagation in similar cultures, becoming possible several clinical applications as skin substitutes or wound dressings in situations such as post burn extensive skin loss and other skin disorders. However, good development of these keratinocytes depends on a high quality feeder layer among other factors. In the present work, we evaluated the relationship between radiation levels and dose rates applied to fibroblasts used in construction of feeder layers and the radiation effect on keratinocytes colonies forming efficiency. Results indicate 3T3 lineage murine fibroblasts irradiated with doses varying between 60 and 100 Gy can be used as a feeder layer immediately after irradiation or storage of the irradiated cells in suspension at 4 g C for 24 hours with similar results. The exception is when the irradiation dose rate is 2.75 Gyh -1 ; in this case, results suggested that the fibroblasts should be used immediately after irradiation. (author)

  10. An efficient hybrid evolutionary algorithm based on PSO and HBMO algorithms for multi-objective Distribution Feeder Reconfiguration

    Energy Technology Data Exchange (ETDEWEB)

    Niknam, Taher [Electronic and Electrical Engineering Department, Shiraz University of Technology, Shiraz (Iran)

    2009-08-15

    This paper introduces a robust searching hybrid evolutionary algorithm to solve the multi-objective Distribution Feeder Reconfiguration (DFR). The main objective of the DFR is to minimize the real power loss, deviation of the nodes' voltage, the number of switching operations, and balance the loads on the feeders. Because of the fact that the objectives are different and no commensurable, it is difficult to solve the problem by conventional approaches that may optimize a single objective. This paper presents a new approach based on norm3 for the DFR problem. In the proposed method, the objective functions are considered as a vector and the aim is to maximize the distance (norm2) between the objective function vector and the worst objective function vector while the constraints are met. Since the proposed DFR is a multi objective and non-differentiable optimization problem, a new hybrid evolutionary algorithm (EA) based on the combination of the Honey Bee Mating Optimization (HBMO) and the Discrete Particle Swarm Optimization (DPSO), called DPSO-HBMO, is implied to solve it. The results of the proposed reconfiguration method are compared with the solutions obtained by other approaches, the original DPSO and HBMO over different distribution test systems. (author)

  11. A look at one of the world`s largest apron feeder drives - Alberta Oil Sands Project

    Energy Technology Data Exchange (ETDEWEB)

    Persson, O. [Hagglunds Drives Canada Inc., Vancouver, BC (Canada)

    1999-10-01

    Various types of equipment to transport tar sands to processing plants are discussed, with special attention to the advantages of hydraulic direct drives over conventional electro-mechanical drives. A hydraulic direct drive such as the Hagglund Drive has exceptional starting torque capacity due to the high torque capability of the hydraulic motor. As such, it can be particularly useful in applications where shock loads occur with some frequency, or where many starts and stops are needed. Application of the Hagglund drive to power one of the world`s largest apron feeders in the Alberta Oil Sands is described as an illustration of the exceptional reliability, productivity and performance of this equipment. It has about one five-hundredth of the inertia of an equivalent high speed drive with gear reducer, a feature which is particularly significant in the case of feeders which are known to suffer much downtime due to chain related problems. These types of drives have also been used to great advantage in the process industries like pulp and paper, chemical, rubber and plastics, recycling and steel. 1 tab., 1 fig.

  12. A look at one of the world's largest apron feeder drives - Alberta Oil Sands Project

    Energy Technology Data Exchange (ETDEWEB)

    Persson, O. (Hagglunds Drives Canada Inc., Vancouver, BC (Canada))

    1999-01-01

    Various types of equipment to transport tar sands to processing plants are discussed, with special attention to the advantages of hydraulic direct drives over conventional electro-mechanical drives. A hydraulic direct drive such as the Hagglund Drive has exceptional starting torque capacity due to the high torque capability of the hydraulic motor. As such, it can be particularly useful in applications where shock loads occur with some frequency, or where many starts and stops are needed. Application of the Hagglund drive to power one of the world's largest apron feeders in the Alberta Oil Sands is described as an illustration of the exceptional reliability, productivity and performance of this equipment. It has about one five-hundredth of the inertia of an equivalent high speed drive with gear reducer, a feature which is particularly significant in the case of feeders which are known to suffer much downtime due to chain related problems. These types of drives have also been used to great advantage in the process industries like pulp and paper, chemical, rubber and plastics, recycling and steel. 1 tab., 1 fig.

  13. A feeder-free, human plasma-derived hydrogel for maintenance of a human embryonic stem cell phenotype in vitro

    Directory of Open Access Journals (Sweden)

    Lewis Fiona C

    2012-08-01

    Full Text Available Abstract Background Human embryonic stem cells (hESCs represent a tremendous resource for cell therapies and the study of human development; however to maintain their undifferentiated state in vitro they routinely require the use of mouse embryonic fibroblast (MEF feeder-layers and exogenous protein media supplementation. Results These well established requirements can be overcome and in this study, it will be demonstrated that phenotypic stability of hESCs can be maintained using a novel, human plasma protein-based hydrogel as an extracellular culture matrix without the use of feeder cell co-culture. hESCs were resuspended in human platelet poor plasma (PPP, which was gelled by the addition of calcium containing DMEM-based hESC culture medium. Phenotypic and genomic expression of the pluripotency markers OCT4, NANOG and SOX2 were measured using immunohistochemistry and qRT-PCR respectively. Typical hESC morphology was demonstrated throughout in vitro culture and both viability and phenotypic stability were maintained throughout extended culture, up to 25 passages. Conclusions PPP-derived hydrogel has demonstrated to be an efficacious alternative to MEF co-culture with its hydrophilicity allowing for this substrate to be delivered via minimally invasive procedures in a liquid phase with polymerization ensuing in situ. Together this provides a novel technique for the study of this unique group of stem cells in either 2D or 3D both in vitro and in vivo.

  14. Establishment of rat embryonic stem-like cells from the morula using a combination of feeder layers.

    Science.gov (United States)

    Sano, Chiaki; Matsumoto, Asako; Sato, Eimei; Fukui, Emiko; Yoshizawa, Midori; Matsumoto, Hiromichi

    2009-08-01

    Embryonic stem (ES) cells are characterized by pluripotency, in particular the ability to form a germline on injection into blastocysts. Despite numerous attempts, ES cell lines derived from rat embryos have not yet been established. The reason for this is unclear, although certain intrinsic biological differences among species and/or strains have been reported. Herein, using Wistar-Imamichi rats, specific characteristics of preimplantation embryos are described. At the blastocyst stage, Oct4 (also called Pou5f1) was expressed in both the inner cell mass (ICM) and the trophectoderm (TE), whereas expression of Cdx2 was localized to the TE. In contrast, at an earlier stage, expression of Oct4 was detected in all the nuclei in the morula. These stages were examined using a combination of feeder layers (rat embryonic fibroblast [REF] for primary outgrowth and SIM mouse embryo-derived thioguanine- and ouabain-resistant [STO] cells for passaging) to establish rat ES-like cell lines. The rat ES-like cell lines obtained from the morula maintained expression of Oct4 over long-term culture, whereas cell lines derived from blastocysts lost pluripotency during early passage. The morula-derived ES-like cell lines showed Oct4 expression in a long-term culture, even after cryogenic preservation, thawing and EGFP transfection. These results indicate that rat ES-like cell lines with long-term Oct4 expression can be established from the morula of Wistar-Imamichi rats using a combination of feeder layers.

  15. Short communication: Milk meal pattern of dairy calves is affected by computer-controlled milk feeder set-up

    DEFF Research Database (Denmark)

    Jensen, Margit Bak

    2009-01-01

    for a minimum of 2 and 4 portions, respectively, whereas low-fed calves ingested their milk in 2.4 and 4.4 meals for a minimum of 2 and 4 portions, respectively. Calves on a high milk allowance had fewer milk meals over time, whereas calves on a low milk allowance had the same number of milk meals throughout...... milk portions, whereas the other half could ingest the milk in 4 or more daily portions. Data were collected during 3 successive 14-d periods, the first period starting the day after introduction to the feeder at minimum 12 d of age. High-fed calves ingested their milk in 4.0 and 4.9 meals....... Thus, the development from small and frequent milk meals to fewer and larger meals reported by studies of natural suckling was also found among high-fed calves on a computer-controlled milk feeder. Irrespectively of minimum number of milk portions, the low-fed calves had more unrewarded visits...

  16. Comparative abundance and distribution of major filter-feeders in the Antarctic pelagic zone

    Science.gov (United States)

    Voronina, N. M.

    1998-11-01

    published P/B coefficients. For the copepods its value was taken as 4.4 and for krill as 0.79. The total annual production of copepods was estimated as 2534 10 6 t and that of krill as 215 10 6 t (fresh mass). Salp production could not be evaluated, for lack of a sufficient database. In terms of fresh mass, the main share of filter-feeder biomass on the entire Antarctic scale belongs to salps, due to their local maxima; the second place belongs to copepods and krill comes in the third position. But after recalculation in terms of dry mass, copepods shift to the first place and salps to the last. The annual production of copepods significantly exceeds that of krill.

  17. Congestion Control Algorithm in Distribution Feeders: Integration in a Distribution Management System

    Directory of Open Access Journals (Sweden)

    Tine L. Vandoorn

    2015-06-01

    Full Text Available The increasing share of distributed energy resources poses a challenge to the distribution network operator (DNO to maintain the current availability of the system while limiting the investment costs. Related to this, there is a clear trend in DNOs trying to better monitor their grid by installing a distribution management system (DMS. This DMS enables the DNOs to remotely switch their network or better localize and solve faults. Moreover, the DMS can be used to centrally control the grid assets. Therefore, in this paper, a control strategy is discussed that can be implemented in the DMS for solving current congestion problems posed by the increasing share of renewables in the grid. This control strategy controls wind turbines in order to avoid congestion while mitigating the required investment costs in order to achieve a global cost-efficient solution. Next to the application and objective of the control, the parameter tuning of the control algorithm is discussed.

  18. Economic viability of distributed energy resources relative to substation and feeder facilities expansion

    DEFF Research Database (Denmark)

    Akorede, M. F.; Hizam, H.; Aris, I.

    2010-01-01

    Distributed energy resources have numerous benefits, of which is transmission network upgrade deferral. This application is particularly important where there are constraints in upgrading of the existing or construction of new generation units and transmission circuits. This paper presents a cost...

  19. Simulasi Dinamika untuk Menentukan Stabilitas Sistem Tenaga Listrik Menggunakan Thyristor Controlled Braking Resistor pada Sistem IEEE 34 Node Test Feeder

    Directory of Open Access Journals (Sweden)

    Andi Taufiq

    2012-09-01

    Full Text Available Terdapat berbagai macam metode untuk meningkatkan stabilitas sistem  tenaga listrik. Salah satunya adalah dengan menggunakan metode pengereman dinamis (dynamic braking. Generator sinkron sebagai distributed generator yang digerakkan oleh mesin diesel. Pada saat terjadi gangguan pada sistem, digunakan sebuah Thyristor Controlled Braking Resistor (TCBR untuk meredam osilasi yang terjadi. Sistem yang hendak dianalisis dinamika dan stabilitasnnya adalah IEEE 34 node test feeder. Dengan sistem ini diilustrasikan karakteristik dan keefektifan TCBR untuk meredam osilasi frekuensi rendah dan mencegah terjadinya ketidakstabilan transien sistem. Dari hasil analisis diperoleh bahwa dengan adanya penambahan TCBR (Thyristor Controlled Braking Resistor maka respon transien sistem akan menjadi lebih baik. Hal ini ditunjukkan dengan adanya penurunan overshoot dan settling timenya. Dengan demikian sistem akan menuju kondisi stabil dengan lebih cepat setelah terjadi gangguan.

  20. Growth factor expression pattern of homologous feeder layer for culturing buffalo embryonic stem cell-like cells.

    Science.gov (United States)

    Sharma, Ruchi; George, Aman; Kamble, Nitin M; Chauhan, Manmohan S; Singla, Suresh; Manik, Radhey S; Palta, Prabhat

    2012-01-01

    The present study examined the expression profile of buffalo fetal fibroblasts (BFF) used as a feeder layer for embryonic stem (ES) cell-like cells. The expression of important growth factors was detected in cells at different passages. Mitomycin-C inactivation increased relative expression levels of ACTIVIN-A, TGF-β1, BMP-4 and GREMLIN but not of fibroblast growth factor-2 (FGF-2). The expression level of ACTIVIN-A, transforming growth factor-β1 (TGF-β1), bone morphogenetic protein-4 (BMP-4) and FGF-2 was similar in buffalo fetal fibroblast (BFF) cultured in stem cell medium (SCM), SCM+1000IU mL(-1) leukemia inhibitory factor (LIF), SCM+5 ngmL(-1) FGF-2 or SCM+LIF+FGF-2 for 24 h whereas GREMLIN expression was higher in FGF-2-supplemented groups. In spent medium, the concentration of ACTIVIN-A was higher in FGF-2-supplemented groups whereas that of TGF-β1 was similar in SCM and LIF+FGF-2, which was higher than when either LIF or FGF-2 was used alone. Following culture of ES cell-like cells on a feeder layer for 24 h, the TGF-β1 concentration was higher with LIF+FGF-2 than with LIF or FGF-2 alone which, in turn, was higher than that in SCM. In the LIF+FGF-2 group, the concentration of TGF-β1 was lower and that of ACTIVIN-A was higher in spent medium at 24 h than at 48 h of culture. These results suggest that BFF produce signalling molecules that may help in self-renewal of buffalo ES cell-like cells.

  1. Development of an extruder-feeder biomass direct liquefaction process. Volume 2, Parts 4--8: Final report

    Energy Technology Data Exchange (ETDEWEB)

    White, D.H.; Wolf, D. [Arizona Univ., Tucson, AZ (United States). Dept. of Chemical Engineering

    1991-10-01

    As an abundant, renewable, domestic energy resource, biomass could help the United States reduce its dependence on imported oil. Biomass is the only renewable energy technology capable of addressing the national need for liquid transportation fuels. Thus, there is an incentive to develop economic conversion processes for converting biomass, including wood, into liquid fuels. Through research sponsored by the US DOE`s Biomass Thermochemical Conversion Program, the University of Arizona has developed a unique biomass direct liquefaction system. The system features a modified single-screw extruder capable of pumping solid slurries containing as high as 60 wt% wood flour in wood oil derived vacuum bottoms at pressures up to 3000 psi. The extruder-feeder has been integrated with a unique reactor by the University to form a system which offers potential for improving high pressure biomass direct liquefaction technology. The extruder-feeder acts simultaneously as both a feed preheater and a pumping device for injecting wood slurries into a high pressure reactor in the biomass liquefaction process. An experimental facility was constructed and following shakedown operations, wood crude oil was produced by mid-1985. By July 1988, a total of 57 experimental continuous biomass liquefaction runs were made using White Birch wood feedstock. Good operability was achieved at slurry feed rates up to 30 lb/hr, reactor pressures from 800 to 3000 psi and temperatures from 350{degree}C to 430{degree}C under conditions covering a range of carbon monoxide feed rates and sodium carbonate catalyst addition. Crude wood oils containing as little as 6--10 wt% residual oxygen were produced. 38 refs., 82 figs., 26 tabs.

  2. Keratinocytes propagated in serum-free, feeder-free culture conditions fail to form stratified epidermis in a reconstituted skin model.

    Directory of Open Access Journals (Sweden)

    Rebecca Lamb

    Full Text Available Primary human epidermal stem cells isolated from skin tissues and subsequently expanded in tissue culture are used for human therapeutic use to reconstitute skin on patients and to generate artificial skin in culture for academic and commercial research. Classically, epidermal cells, known as keratinocytes, required fibroblast feeder support and serum-containing media for serial propagation. In alignment with global efforts to remove potential animal contaminants, many serum-free, feeder-free culture methods have been developed that support derivation and growth of these cells in 2-dimensional culture. Here we show that keratinocytes grown continually in serum-free and feeder-free conditions were unable to form into a stratified, mature epidermis in a skin equivalent model. This is not due to loss of cell potential as keratinocytes propagated in serum-free, feeder-free conditions retain their ability to form stratified epidermis when re-introduced to classic serum-containing media. Extracellular calcium supplementation failed to improve epidermis development. In contrast, the addition of serum to commercial, growth media developed for serum-free expansion of keratinocytes facilitated 3-dimensional stratification in our skin equivalent model. Moreover, the addition of heat-inactivated serum improved the epidermis structure and thickness, suggesting that serum contains factors that both aid and inhibit stratification.

  3. Feeding current characteristics of three morphologically different bivalve suspension feeders, Crassostrea gigas, Mytilus edulis and Cerastoderma edule, in relation to food competition

    NARCIS (Netherlands)

    Troost, K.; Stamhuis, E.J.; van Duren, L.A; Wolff, W.J.

    Introduced Pacific oysters (Crassostrea gigas) have shown rapid expansion in the Oosterschelde estuary, while stocks of native bivalves declined slightly or remained stable. This indicates that they might have an advantage over native bivalve filter feeders. Hence, at the scale of individual

  4. 47 CFR 25.223 - Off-axis EIRP spectral density limits for feeder link earth stations in the 17/24 GHz BSS.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Off-axis EIRP spectral density limits for feeder link earth stations in the 17/24 GHz BSS. 25.223 Section 25.223 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES SATELLITE COMMUNICATIONS Technical Standards § 25...

  5. 47 CFR 25.258 - Sharing between NGSO MSS Feeder links Stations and GSO FSS services in the 29.25-29.5 GHz Bands.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Sharing between NGSO MSS Feeder links Stations and GSO FSS services in the 29.25-29.5 GHz Bands. 25.258 Section 25.258 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES SATELLITE COMMUNICATIONS Technical Standards § 25...

  6. Network integration modelling of feeder and BRT(bus rapid transit) to reduce the usage of private vehicles in Palembang’s suburban area

    Science.gov (United States)

    Nur'afalia, D.; Afifa, F.; Rubianto, L.; Handayeni, K. D. M. E.

    2018-01-01

    The aim of this research is to determine the optimal feeder network route that integrates with BRT (Bus Rapid Transit). Palembang, a high growing population city with unresolved transportation demand sector. BRT as main public transportation could not fulfill people’s demand in transportation, especially in Alang-Alang Lebar sub-district. As an impact, the usage of private vehicles increases along the movement toward the city center. The concept of Network Integration that integrates feeder network with BRT is expected to be a solution to suppress the rate of private vehicles’ usage and to improve public transportation service, so that the use of BRT will be increased in the suburban area of Palembang. The method used to identifying the optimal route using Route Analysis method is route analysis using Tranetsim 0.4. The best route is obtained based on 156 movement samples. The result is 58,7% from 199 mobility’s potency of private vehicle usage’s can be reduced if there is a feeder network’s route in Alang-Alang Lebar’s sub-district. From the result, the existance of integration between feeder network and BRT is potential enough to reduce the usage of private vehicles and supports the sustainability of transportation mobility in Palembang City.

  7. Cultivation and irradiation of human fibroblasts in a medium enriched with platelet lysate for obtaining feeder layer in epidermal cell culture

    International Nuclear Information System (INIS)

    Yoshito, Daniele

    2011-01-01

    For over 30 years, the use of culture medium, enriched with bovine serum, and murines fibroblasts, with the rate of proliferation controlled by irradiation or by share anticarcinogenic drugs, has been playing successfully its role in assisting in the development of keratinocytes in culture, for clinical purposes. However, currently there is a growing concern about the possibility of transmitting prions and animals viruses to transplanted patients. Taking into account this concern, the present work aims to cultivate human fibroblasts in a medium enriched with human platelets lysate and determine the irradiation dose of these cells, for obtaining feeder layer in epidermal cell culture. For carrying out the proposed objective, platelets lysis has standardized, this lysate was used for human fibroblasts cultivation and the irradiation dose enough to inhibit its duplication was evaluated. Human keratinocytes were cultivated in these feeder layers, in culture medium enriched with the lysate. With these results we conclude that the 10% platelets lysate promoted a better adhesion and proliferation of human fibroblasts and in all dose levels tested (60 to 300 Gy), these had their mitotic activity inactivated by ionizing irradiation, being that the feeder layers obtained with doses from 70 to 150 Gy were those that provided the best development of keratinocytes in medium containing 2.5% of human platelet lysate. Therefore, it was possible to standardize both the cultivation of human fibroblasts as its inactivation for use as feeder layer in culture of keratinocytes, so as to eliminate xenobiotics components. (author)

  8. Feeding current characteristics of three morphologically different bivalve suspension feeders, Crassostrea gigas Mytilus edulis and Cerastoderma edule , in relation to food competition

    NARCIS (Netherlands)

    Troost, K.; Stamhuis, E.J.; Duren, L.A.; Wolff, W.

    2009-01-01

    Introduced Pacific oysters (Crassostrea gigas) have shown rapid expansion in the Oosterschelde estuary, while stocks of native bivalves declined slightly or remained stable. This indicates that they might have an advantage over native bivalve filter feeders. Hence, at the scale of individual

  9. Effect of stall design on dairy calf transition to voluntary feeding on an automatic milk feeder after introduction to group housing.

    Science.gov (United States)

    Wilson, Tanya R; LeBlanc, Stephen J; DeVries, Trevor J; Haley, Derek B

    2018-06-01

    Automatic milk feeders (AMF) for young dairy calves are widely used in the dairy industry. These feeders are thought to have benefits for calf health and welfare and may reduce labor required for feeding; however, little is known about how calves adapt to feeding with AMF. The objective of this study was to observe the effects of feeding stall design on calves learning to use the AMF. The hypothesis was that solid side stalls, compared with steel bar stalls, would result in a longer latency to approach and feed from the AMF without assistance. A total of 147 Holstein calves (80 male and 67 female) were enrolled at 4 d of age, introduced to a group pen, and, at the same time, trained on an AMF. For training, calves were allowed to suck on the trainer's fingers and guided to the teat. Calves were allocated to 1 of 2 stall designs at the pen level, depending on which treatment cohort they were born into, either with steel bar stall walls (n = 46 male, 34 female calves) or with solid side stall walls (n = 34 male, 33 female calves). For 72 h after introductory training on the AMF, data from the feeders were collected and calf behavior was monitored by video. Outcomes measured included latency to first voluntary visit to the feeder and to first feeding, time spent in the feeder, amount of milk consumed over 72 h, number of retraining sessions required (retrained if linear regression models or a Poisson model for the outcome of retraining. For certain outcomes the effects of stall design interacted with difficulty of training (willingness to enter feeder and drink); for the 38% of calves that were scored as moderately difficult to train on a scale of easy, moderate, or difficult, treatment (stall design) differences were detected. These calves took 2× longer to lick or bite toward the nipple, 2× longer to first voluntarily feeding, and consumed less milk over 72 h following training when trained on the steel bar stall design. These results suggest simple features of a

  10. Measurements of local mass transfer coefficient of Flow Accelerated Corrosion at feeder outlet pipes in CANDU using Plaster of Paris method

    International Nuclear Information System (INIS)

    Hyuk Kwon; Dong Un Seo; Goon-Cherl Park

    2005-01-01

    Full text of publication follows: Flow Accelerated Corrosion (FAC) is a corrosion mechanism that results in wall thinning in piping systems and components. FAC on carbon steels in pure water has occurred in a number of industry and power plant. A pipe wall thinning due to the FAC at nuclear power plant is just reported in confined to carbon steel pipe on the secondary system which does not equip a radioactive component. Recently, at Canadian Deuterium Uranium type reactor, it is reported that the feeder lines suffer the wall thinning on the primary system to equip 380 feeder pipes. Differently from the fast FAC rate of the secondary system on PWR, FAC rate of feeder pipes on CANDU is not more than the 0.2 mm/year. Although the FAC rate of feeder pipe is relatively slow, the narrow thickness margin of 2.6089 mm is endangered sufficiently by only the slow FAC rate. The FAC is governed by the mass transfer coefficient which is determined by the flow field. To well predict the FAC rate, mass transfer coefficient should be well measured or calculated. New measurement method of mass transfer coefficient is developed to obtain the coefficient for the complex shape like feeder pipe. The method evaluated the naphthalene sublimation method to apply it under the water flow. The naphthalene sublimation method can be used to study mass and heat transfer with confidence for a variety of applications, but with certain restrictions. At present, Plaster of paris method can modified the sublimation method to overcome the restrictions. This method is particularly useful in complex flows on geometries and for flows with large gradients in wall transport rate. The test specimen can be easily prepared by several methods, including dipping, machining, spraying, and casting. The local transfer coefficients can be determined with high accuracy and in detail by automated measurement systems that eliminate most human errors during the measurement process. To evaluate the method, the

  11. Flow visualization study of two phase flow in a single bend outlet feeder pipe and horizontal annulus of outlet end-fitting of a CANDU reactor

    International Nuclear Information System (INIS)

    Supa-Amornkul, S.; Lister, D.H.; Steward, F.R.

    2005-01-01

    'Full text:' In CANDU-6 reactors, the pressurized high-temperature coolant flows through 380 fuel channels passing horizontally through the core. Each end of a fuel channel has a stainless steel annular end-fitting connected to a carbon steel feeder pipe. The outlet coolant, which is at 310 o C with up to 0.30 steam voidage, turns through 90 o as it passes from flow in the annular end-fitting to pipe flow in the feeder via a Grayloc connector. Since 1996, several CANDU stations have reported excessive corrosion of their outlet feeder pipes; especially between the first metre, which consisted of single or double bends. Early studies related the attack to the hydrodynamics of the coolant and verified that it was a type of flow accelerated corrosion. In order to understand the hydrodynamics of the coolant in the outlet feeders by flow-visualization, a full-scale transparent test section simulating the geometry and orientation of an outlet feeder bend with its upstream annular end-fitting were fabricated. The feeder consisted of a 54 mm inside diameter acrylic pipe with a 73 o bend, connecting to an acrylic simulation of a Grayloc flanged fitting and annular end-fitting. The annular end-fitting consisted of an inner pipe, 110 mm outer diameter, and an outer pipe, 150 mm inner diameter, both 190.7 cm long in length. The tests were performed with water and air at atmospheric pressure and room temperature. The maximum water volumetric flow rate was 19 L/s and the volume fraction of air varied from 0.05 to 0.56. The phase distributions within the feeder pipe and along the length of the annulus were investigated with a digital video recorder. Size, concentration and velocity of the air bubbles at particular locations were studied with a high-speed digital still camera and a high-speed digital video camera. Phase distributions and variations in bubble size with velocity were determined. Particular attention was paid to the flow pattern at the inside of the bend, where a CFD

  12. Flow visualization study of two phase flow in a single bend outlet feeder pipe and horizontal annulus of outlet end-fitting of a CANDU reactor

    Energy Technology Data Exchange (ETDEWEB)

    Supa-Amornkul, S.; Lister, D.H.; Steward, F.R. [Univ. of New Brunswick, Fredericton, New Brunswick (Canada)]. E-mail: h796e@unb.ca; dlister@unb.ca; fsteward@unb.ca

    2005-07-01

    'Full text:' In CANDU-6 reactors, the pressurized high-temperature coolant flows through 380 fuel channels passing horizontally through the core. Each end of a fuel channel has a stainless steel annular end-fitting connected to a carbon steel feeder pipe. The outlet coolant, which is at 310{sup o}C with up to 0.30 steam voidage, turns through 90{sup o} as it passes from flow in the annular end-fitting to pipe flow in the feeder via a Grayloc connector. Since 1996, several CANDU stations have reported excessive corrosion of their outlet feeder pipes; especially between the first metre, which consisted of single or double bends. Early studies related the attack to the hydrodynamics of the coolant and verified that it was a type of flow accelerated corrosion. In order to understand the hydrodynamics of the coolant in the outlet feeders by flow-visualization, a full-scale transparent test section simulating the geometry and orientation of an outlet feeder bend with its upstream annular end-fitting were fabricated. The feeder consisted of a 54 mm inside diameter acrylic pipe with a 73{sup o} bend, connecting to an acrylic simulation of a Grayloc flanged fitting and annular end-fitting. The annular end-fitting consisted of an inner pipe, 110 mm outer diameter, and an outer pipe, 150 mm inner diameter, both 190.7 cm long in length. The tests were performed with water and air at atmospheric pressure and room temperature. The maximum water volumetric flow rate was 19 L/s and the volume fraction of air varied from 0.05 to 0.56. The phase distributions within the feeder pipe and along the length of the annulus were investigated with a digital video recorder. Size, concentration and velocity of the air bubbles at particular locations were studied with a high-speed digital still camera and a high-speed digital video camera. Phase distributions and variations in bubble size with velocity were determined. Particular attention was paid to the flow pattern at the inside

  13. Effect of feeder space during the growing and laying periods and the rate of feed increase at the onset of lay on broiler breeder female reproductive function.

    Science.gov (United States)

    Leksrisompong, N; Romero-Sanchez, H; Oviedo-Rondón, E O; Brake, J

    2014-07-01

    A study was conducted to examine how 2 feeder space allocations during the rearing period followed by 2 feeder space allocations after photostimulation and 2 female feeding to peak programs (fast or slow) affected female broiler breeder reproductive performance and mortality. Sixteen pens of 76 breeder females each were equipped with either 4 tube feeders with a 132 cm circumference pan (7.0 cm/female) or 6 feeders (10.4 cm/female) to 21 wk of age. Thereafter, 64 females were moved to breeding pens, photostimulated, and fed sex-separate from either 3 (6.2 cm/female) or 5 (10.3 cm/female) feeders with either fast or slow feeding to peak feeding programs applied to complete a 2 × 2 × 2 factorial design. Seven males that were separately reared in a similar manner were added per pen. Individual female BW was determined at 6, 20, and 32 wk of age and BW uniformity assessed. Greater feeder space during rearing increased BW at 32 wk of age, whereas greater feeder space during lay or slow feeding to peak decreased BW at 32 wk. There were no differences in BW uniformity. Hens from the 10.4 to 10.3 cm/female combination produced a significantly greater number of eggs as compared with the 7.0 to 10.3 cm/female and 10.4 to 6.2 cm/female combinations with the 7.0 to 6.2 cm/female combination intermediate. Percentage hen-day egg production of the 10.4 to 10.3 cm/female combination hens was significantly greater than all other combinations. Livability was improved in the 10.4 to 10.3 cm/female combination relative to the 7.0 to 10.3 cm/female combination with the others intermediate. The fast feeding to peak program increased yolk weight as well as yolk:albumen ratio at 28 and 30 wk of age, but egg weight did not differ. These data indicated that increased or decreased feeder space between the growing and laying periods did not affect broiler breeder female BW, uniformity, egg weight, fertility, or hatchability. The 10.3 cm/female laying feeder space exhibited the best hen

  14. The effect of a hay grid feeder on feed consumption and measurement of the gastric pH using an intragastric electrode device in horses: a preliminary report.

    Science.gov (United States)

    Aristizabal, F; Nieto, J; Yamout, S; Snyder, J

    2014-07-01

    Obesity and gastric ulceration are highly prevalent in horses. Management modifications for preventing squamous gastric ulceration include frequent feeding and free access to pasture; however, these practices may predispose horses to obesity. To compare the percentage of hay consumed, intragastric pH and horse activity between feeding from the ground and a hay grid feeder. Crossover experimental study. A pH electrode was inserted into the stomach to record the intragastric pH for 48 h. Horses received 1% of their body weight in grass hay twice a day. Horses were assigned to be fed from the ground or a commercial hay grid feeder for 24 h and then switched to the opposite protocol for an additional 24 h. Horses were continuously video-recorded and the percentage of time spent eating or drinking, walking or standing, and lying down were calculated. Two point data were compared by paired t test and pH over time was compared by repeated measures ANOVA. Horses consumed significantly greater amounts of grass hay when fed on the ground compared with a hay grid feeder (n = 9; PpH values (n = 6; P = 0.97), mean intragastric pH over time (n = 6; P = 0.45) the length of time the pH was below 4.0 (n = 6; P = 0.54), and the percentage of time horses spent eating or drinking (n = 9; P = 0.52), walking or standing (n = 9; P = 0.3), or lying down (n = 9; P = 0.4). Within each group horses spent more time eating during the day compared with the night (n = 9; hay grid feeder P = 0.003; ground feeding P = 0.007). The hay grid feeder studied may be used to reduce the amount of hay ingested by horses without reducing the time horses spend eating. © 2013 EVJ Ltd.

  15. Assessment of Fuel Analysis Methodology and Fission Product Release for 37-Element Fuel by Using the Latest IST Codes during Stagnation Feeder Break in CANDU

    International Nuclear Information System (INIS)

    Park, Joo Hwan; Jung, Jong Yeob

    2009-09-01

    Feeder break accident is regarded as one of the design basis accident in CANDU reactor which results in a fuel failure. For a particular range of inlet feeder break sizes, the flow in the channel is reduced sufficiently that the fuel and fuel channel integrity can be significantly affected to have damage in the affected channel, while the remainder of the core remains adequately cooled. The flow in the downstream channel can be more or less stagnated due to a balance between pressure at the break on the upstream side and the reverse driving pressure between the break and the downstream end. In the extreme, this can lead to rapid fuel heatup and fuel damage and failure of the fuel channel similar to that associated with a severe channel flow blockage. Such an inlet feeder break scenario is called a stagnation break. In this report, the fuel analysis methodology and the assessment results of fission product inventory and release during the stagnation feeder break are described for conservatively assumed limiting channel. The accident was assumed to be occurred in the refurbished Wolsong unit 1 and the latest safety codes were used in the analysis. Fission product inventories during the steady state were calculated by using ELESTRES-IST 1.2 code. The whole analysis process was carried out by a script file which was programmed by Perl language. The perl script file was programmed to make all ELESTRES input files for each bundle and each ring based on the given power-burnup history and thermal-hydraulic conditions of the limiting channel and to perform the fuel analysis automatically. The fission product release during the transient period of stagnation feeder break was evaluated by applying Gehl model. The amounts of each isotope's release are conservatively evaluated for additional 2 seconds after channel failure. The calculated fission product releases are provided to the following dose assessment as a source term

  16. Cost/worth assessment of reliability improvement in distribution networks by means of artificial intelligence

    Energy Technology Data Exchange (ETDEWEB)

    Bouhouras, Aggelos S.; Labridis, Dimitris P.; Bakirtzis, Anastasios G. [Power Systems Laboratory, Aristotle University of Thessaloniki, Dept. of Electrical and Computer Engineering, 54124 Thessaloniki (Greece)

    2010-06-15

    A major challenge for the power utilities today is to ensure a high level of reliability of supply to customers. Two main factors determine the feasibility of a project that improves the reliability of supply: the project cost (investment and operational) and the benefits that result from the implementation of the project. This paper examines the implementation of an Artificial Intelligence System in an urban distribution network, capable to locate and isolate short circuit faults in the feeder, thus accomplishing immediate restoration of electric supply to the customers. The paper describes the benefits of the project, which are supply reliability improvement and distribution network loss reduction through network reconfigurations. By comparison of the project benefits and costs the economic feasibility of such a project for an underground distribution feeder in Greece is demonstrated. (author)

  17. Air Cargo Development in the Regional Airports of the Baltic Sea Region Through Road Feeder Services

    Directory of Open Access Journals (Sweden)

    Beifert Anatoli

    2015-06-01

    Full Text Available As issued in the Competition Policy Brief on the new state aid rules for a competitive aviation industry by the Competition Directorate-General of the European Commission in February 20141, it will be more difficult for unprofitable airports, to obtain financial public subsidies on EU, national or regional level. Although the positive impact of small airports on the regional development and general accessibility was mentioned, still the operating aid to the airports shall be cut out over a maximum of 10 years. It has been further stated that the vast majority of small and regional airports experience problems to cover their running operative costs, as a result from an intensive market competition and overlapping of airports’ catchment areas preventing even some promising airports from growth. Public subsidies are mostly used by the airport management for infrastructural investments, to cover operating losses or to attract price-sensitive airlines. Herewith, among other things, the EU Commission is pointing out at the lack of cooperation structures and network strategies among the regional airports and at rather isolated and individual approach during elaboration of the airport development scenarios. However, the Competition Policy Brief permits public aid to regional airports, among other things if there is sufficient transports need to establish transition periods for small airports; the need for more flexibility of the regional airports in the remote areas has been underlined. The EU Commission is expecting herewith not to close the regional airports, but to stimulate them to operate on cost efficient and profitable basis, and that only the most inefficient airports will be closed.

  18. Optimation of Operation System Integration between Main and Feeder Public Transport (Case Study: Trans Jakarta-Kopaja Bus Services)

    Science.gov (United States)

    Miharja, M.; Priadi, Y. N.

    2018-05-01

    Promoting a better public transport is a key strategy to cope with urban transport problems which are mostly caused by a huge private vehicle usage. A better public transport service quality not only focuses on one type of public transport mode, but also concerns on inter modes service integration. Fragmented inter mode public transport service leads to a longer trip chain as well as average travel time which would result in its failure to compete with a private vehicle. This paper examines the optimation process of operation system integration between Trans Jakarta Bus as the main public transport mode and Kopaja Bus as feeder public transport service in Jakarta. Using scoring-interview method combined with standard parameters in operation system integration, this paper identifies the key factors that determine the success of the two public transport operation system integrations. The study found that some key integration parameters, such as the cancellation of “system setoran”, passenger get in-get out at official stop points, and systematic payment, positively contribute to a better service integration. However, some parameters such as fine system, time and changing point reliability, and information system reliability are among those which need improvement. These findings are very useful for the authority to set the right strategy to improve operation system integration between Trans Jakarta and Kopaja Bus services.

  19. From steep feeders to tabular plutons - Emplacement controls of syntectonic granitoid plutons in the Damara Belt, Namibia

    Science.gov (United States)

    Hall, Duncan; Kisters, Alexander

    2016-01-01

    Granitoid plutons in the deeply eroded south Central Zone of the Damara Belt in Namibia commonly show tabular geometries and pronounced stratigraphic controls on their emplacement. Subhorizontal, sheet-like pluton geometries record emplacement during regional subhorizontal shortening, but the intrusion of spatially and temporally closely-related granitoid plutons at different structural levels and in distinct structural settings suggests independent controls on their levels of emplacement. We describe and evaluate the controls on the loci of the dyke-to-sill transition that initiated the emplacement of three syntectonic (560-530 Ma) plutons in the basement-cover stratigraphy of the Erongo region. Intrusive relationships highlight the significance of (1) rigidity anisotropies associated with competent sedimentary packages or pre-existing subhorizontal granite sheets and (2) rheological anisotropies associated with the presence of thick ductile marble horizons. These mechanical anisotropies may lead to the initial deflection of steep feeder conduits as well as subsequent pluton assembly by the repeated underaccretion of later magma batches. The upward displacement of regional isotherms due to the heat advection associated with granite emplacement is likely to have a profound effect on the mechanical stratification of the upper crust and, consequently, on the level at which granitoid pluton emplacement is initiated. In this way, pluton emplacement at progressively shallower crustal depths may have resulted in the unusually high apparent geothermal gradients recorded in the upper crustal levels of the Damara Belt during its later evolution.

  20. Bacterial Feeders, the Nematode Caenorhabditis elegans and the Flagellate Cercomonas longicauda, have different Effects on Outcome of Competition among the Pseudomonas Biocontrol Strains CHA0 and DSS73

    DEFF Research Database (Denmark)

    Pedersen, Annette; Nybroe, Ole; Winding, Anne

    2009-01-01

    How bacterial feeding fauna affects colonization and survival of bacteria in soil is not well understood, which constrains the applicability of bacterial inoculants in agriculture. This study aimed to unravel how food quality of bacteria and bacterial feeders with different feeding habits (the......50090 or one of two biocontrol strains P. fluorescens CHA0 or Pseudomonas sp. DSS73) or combinations of two bacterial strains. DSM50090 is a suitable food bacterium, DSS73 is of intermediate food quality, and CHA0 is inedible to the bacterial feeders. Bacterial and protozoan cell numbers were measured...... predation pressure. Hence, the results suggested that the outcome of competition among bacteria depended on their ability to cope with the prevailing bacterial predator....

  1. Artificial blood feeders for mosquito and ticks-Where from, where to?

    Science.gov (United States)

    Romano, Donato; Stefanini, Cesare; Canale, Angelo; Benelli, Giovanni

    2018-07-01

    Mosquito and tick feeding activity represent a key threat for humans, livestock, pets and wildlife worldwide. Rearing these vectors in laboratory conditions is extremely important to investigate basic facets of their biology, vector competence, new control strategies, as well as mechanisms of pesticide resistance. However, the use of animals or humans to provide blood for hematophagous arthropod feeding poses a strict limit to these researches, due to the accidental transmission of diseases, ethical problems concerning animal welfare, as well as expensive and time-consuming animal rearing procedures. The use of devices to artificially feed arthropod vectors can importantly leverage progresses in parasitology and entomology. The aim of this review is to summarize current knowledge about artificial feeding of mosquitoes and ticks, focusing on key concepts and case studies about the design and fabrication of blood feeding devices. From a technical standpoint, the literature analyzed here showed little standardization of materials used for fabricating membrane interfaces, as well as in the strategy used to heat the "biomimetic host". In addition, a lack of uniform methods to design an architecture merging complex and realistic cues with an easy-to-assemble approach have been found. Some commercial products are available, but they are quite expensive, thus hard to reach for many laboratories, especially in developing countries. An important challenge for future research is represented by the introduction of automation and bioinspired engineered solutions in these devices, improving the effectiveness of blood-feeding systems by increasing their host-mimicking features. Automation can reduce labor costs and provide interesting solutions - in line with the 3R principle "reduce, replace and refine" - aimed to minimize the employ of experimental animals in research. Copyright © 2018 Elsevier B.V. All rights reserved.

  2. THE METHOD OF SELECTION OF THE SETPOINT HIGH SPEED FEEDER SWITCH OF 3,3KV DC WITH MICROPROCESSOR-BASED PROTECTION SYSTEMS

    Directory of Open Access Journals (Sweden)

    P. Ye. Mykhalichenko

    2009-10-01

    Full Text Available In the article a new procedure of choice of minimum current jump for action of fast-acting switches of 3.3 kV DC traction substations intended for the use in the microprocessor protection system of feeders is described. This procedure is more perfect than existing one on the current increment and uses the results of mathematical simulation of the traction electric supply system.

  3. Differentiation of monkey embryonic stem cells to hepatocytes by feeder-free dispersion culture and expression analyses of cytochrome p450 enzymes responsible for drug metabolism.

    Science.gov (United States)

    Maruyama, Junya; Matsunaga, Tamihide; Yamaori, Satoshi; Sakamoto, Sakae; Kamada, Noboru; Nakamura, Katsunori; Kikuchi, Shinji; Ohmori, Shigeru

    2013-01-01

    We reported previously that monkey embryonic stem cells (ESCs) were differentiated into hepatocytes by formation of embryoid bodies (EBs). However, this EB formation method is not always efficient for assays using a large number of samples simultaneously. A dispersion culture system, one of the differentiation methods without EB formation, is able to more efficiently provide a large number of feeder-free undifferentiated cells. A previous study demonstrated the effectiveness of the Rho-associated kinase inhibitor Y-27632 for feeder-free dispersion culture and induction of differentiation of monkey ESCs into neural cells. In the present study, the induction of differentiation of cynomolgus monkey ESCs (cmESCs) into hepatocytes was performed by the dispersion culture method, and the expression and drug inducibility of cytochrome P450 (CYP) enzymes in these hepatocytes were examined. The cmESCs were successfully differentiated into hepatocytes under feeder-free dispersion culture conditions supplemented with Y-27632. The hepatocytes differentiated from cmESCs expressed the mRNAs for three hepatocyte marker genes (α-fetoprotein, albumin, CYP7A1) and several CYP enzymes, as measured by real-time polymerase chain reaction. In particular, the basal expression of cmCYP3A4 (3A8) in these hepatocytes was detected at mRNA and enzyme activity (testosterone 6β-hydroxylation) levels. Furthermore, the expression and activity of cmCYP3A4 (3A8) were significantly upregulated by rifampicin. These results indicated the effectiveness of Y-27632 supplementation for feeder-free dispersed culture and induction of differentiation into hepatocytes, and the expression of functional CYP enzyme(s) in cmESC-derived hepatic cells.

  4. A Frequency-Based Assignment Model under Day-to-Day Information Evolution of Oversaturated Conditions on a Feeder Bus Service

    Directory of Open Access Journals (Sweden)

    Silin Zhang

    2017-02-01

    Full Text Available Day-to-day information is increasingly being implemented in transit networks worldwide. Feeder bus service (FBS plays a vital role in a public transit network by providing feeder access to hubs and rails. As a feeder service, a space-time path for frequent passengers is decided by its dynamic strategy procedure, in which a day-to-day information self-learning mechanism is identified and analyzed from our survey data. We formulate a frequency-based assignment model considering day-to-day evolution under oversaturated conditions, which takes into account the residual capacity of bus and the comfort feelings of sitting or standing. The core of our proposed model is to allocate the passengers on each segment belonging to their own paths according to multi-utilities transformed from the time values and parametric demands, such as frequency, bus capacity, seat comfort, and stop layout. The assignment method, albeit general, allows us to formulate an equivalent optimization problem in terms of interaction between the FBS’ operation and frequent passengers’ rational behaviors. Finally, a real application case is generated to test the ability of the modeling framework capturing the theoretical consequents, serving the passengers’ dynamic externalities.

  5. Efficient Generation and Editing of Feeder-free IPSCs from Human Pancreatic Cells Using the CRISPR-Cas9 System.

    Science.gov (United States)

    Nandal, Anjali; Mallon, Barbara; Telugu, Bhanu P

    2017-11-08

    Embryonic and induced pluripotent stem cells can self-renew and differentiate into multiple cell types of the body. The pluripotent cells are thus coveted for research in regenerative medicine and are currently in clinical trials for eye diseases, diabetes, heart diseases, and other disorders. The potential to differentiate into specialized cell types coupled with the recent advances in genome editing technologies including the CRISPR/Cas system have provided additional opportunities for tailoring the genome of iPSC for varied applications including disease modeling, gene therapy, and biasing pathways of differentiation, to name a few. Among the available editing technologies, the CRISPR/Cas9 from Streptococcus pyogenes has emerged as a tool of choice for site-specific editing of the eukaryotic genome. The CRISPRs are easily accessible, inexpensive, and highly efficient in engineering targeted edits. The system requires a Cas9 nuclease and a guide sequence (20-mer) specific to the genomic target abutting a 3-nucleotide "NGG" protospacer-adjacent-motif (PAM) for targeting Cas9 to the desired genomic locus, alongside a universal Cas9 binding tracer RNA (together called single guide RNA or sgRNA). Here we present a step-by-step protocol for efficient generation of feeder-independent and footprint-free iPSC and describe methodologies for genome editing of iPSC using the Cas9 ribonucleoprotein (RNP) complexes. The genome editing protocol is effective and can be easily multiplexed by pre-complexing sgRNAs for more than one target with the Cas9 protein and simultaneously delivering into the cells. Finally, we describe a simplified approach for identification and characterization of iPSCs with desired edits. Taken together, the outlined strategies are expected to streamline generation and editing of iPSC for manifold applications.

  6. Mixed xylem and phloem sap ingestion in sheath-feeders as normal dietary behavior: Evidence from the leafhopper Scaphoideus titanus.

    Science.gov (United States)

    Chuche, Julien; Sauvion, Nicolas; Thiéry, Denis

    2017-10-01

    In phytophagous piercing-sucking insects, salivary sheath-feeding species are often described as xylem- or phloem-sap feeding specialists. Because these two food sources have very different characteristics, two feeding tactics are often associated with this supposed specialization. Studying the feeding behavior of insects provides substantial information on their biology, ecology, and evolution. Furthermore, study of feeding behavior is of primary importance to elucidate the transmission ability of insects that act as vectors of plant pathogens. In this study, we compared the durations of ingestion performed in xylem versus phloem by a leafhopper species, Scaphoideus titanus Ball, 1932. This was done by characterizing and statistically analyzing electrical signals recorded using the electropenetrography technique, derived from the feeding behaviors of males and females. We identified three groups of S. titanus based on their feeding behavior: 1) a group that reached the phloem quickly and probed for a longer time in phloem tissue than the other groups, 2) a group that reached the xylem quickly and probed for a longer time in xylem tissue than the other groups, and 3) a group where individuals did not ingest much sap. In addition, the numbers and durations of waveforms representing ingestion of xylem and phloem saps differed significantly depending on the sex of the leafhopper, indicating that the two sexes exhibit different feeding behaviors. Males had longer phloem ingestion events than did females, which indicates that males are greater phloem feeders than females. These differences are discussed, specifically in relation to hypotheses about evolution of sap feeding and phytoplasma transmission from plant to plant. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Application of a computer model to predict optimum slaughter end points for different biological types of feeder cattle.

    Science.gov (United States)

    Williams, C B; Bennett, G L

    1995-10-01

    A bioeconomic model was developed to predict slaughter end points of different genotypes of feeder cattle, where profit/rotation and profit/day were maximized. Growth, feed intake, and carcass weight and composition were simulated for 17 biological types of steers. Distribution of carcass weight and proportion in four USDA quality and five USDA yield grades were obtained from predicted carcass weights and composition. Average carcass value for each genotype was calculated from these distributions under four carcass pricing systems that varied from value determined on quality grade alone to value determined on yield grade alone. Under profitable market conditions, rotation length was shorter and carcass weights lighter when the producer's goal was maximum profit/day, compared with maximum profit/rotation. A carcass value system based on yield grade alone resulted in greater profit/rotation and in lighter and leaner carcasses than a system based on quality grade alone. High correlations ( > .97) were obtained between breed profits obtained with different sets of input/output prices and carcass price discount weight ranges. This suggests that breed rankings on the basis of breed profits may not be sensitive to changes in input/output market prices. Steers that were on a grower-stocker system had leaner carcasses, heavier optimum carcass weight, greater profits, and less variation in optimum carcass weights between genotypes than steers that were started on a high-energy finishing diet at weaning. Overall results suggest that breed choices may change with different carcass grading and value systems and postweaning production systems. This model has potential to provide decision support in marketing fed cattle.

  8. Wean-to-finish feeder space availability effects on nursery and finishing pig performance and total tract digestibility in a commercial setting when feeding dried distillers grains with solubles.

    Science.gov (United States)

    Weber, E K; Stalder, K J; Patience, J F

    2015-04-01

    The study objectives were to determine nursery phase feeder space allowance effects on pig performance when double stocked and, second, to determine feeder space allowance and dried distillers grains with solubles (DDGS) inclusion level effects on pig performance and nutrient digestibility during the growing-finishing phase. This study was performed on the same group of pigs within a commercial wean-finish system. For the nursery phase, a completely randomized design was used to compare 3 feeder space allowance treatments (2.1, 2.5, and 2.9 cm/pig). A total of 3,720 pigs were randomly allotted to same-sex pens (10 feeders/treatment) housing 62 pigs/pen. Thirty 7-hole, double-sided feeders were utilized in the study. Differing linear feeder space treatments were established by blocking off sections for the nursery and grow-finish portions of this experiment. All pigs were provided equal floor space (0.26 m2/pig). In the grow-finish phase, a total of 1,860 pigs (n = 60 pens) were utilized in a 2 × 3 factorial design with 3 feeder space allowances (4.1, 4.9, or 5.7 cm/pig) and 2 dietary DDGS treatments (30% [D30] or 60% [D60]). Fecal and diet samples were collected and analyzed to estimate apparent total tract digestibility percentage (ATTD %). In the nursery portion of the trial, there was no feeder space treatment effect on ADG, ADFI, or feed efficiency (P > 0.10) from weaning to d 56 postweaning or during any weigh period. In the grow-finish portion of the trial, feeder space allowance and DDGS inclusion level did not affect ADG, ADFI, or feed efficiency (P > 0.05) from d 57 postweaning to market. Pigs fed the D30 diet had greater HCW, percent yield, and loin depth than those on the D60 diet (P feeder space allowance did not impact pig performance during the nursery or grow-finish production phases. Inclusion of DDGS at higher levels will decrease ADFI but not ADG or efficiency when isocaloric diets are fed. The inclusion level of DDGS does impact HCW and percent

  9. Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium.

    Directory of Open Access Journals (Sweden)

    Marjorie Pick

    Full Text Available BACKGROUND: The production of human platelets from embryonic stem cells in a defined culture system is a prerequisite for the generation of platelets for therapeutic use. As an important step towards this goal, we report the differentiation of human embryonic stem cells (hESCs towards the megakaryocyte (Mk lineage using a 'spin embryoid body' method in serum-free differentiation medium. METHODOLOGY AND PRINCIPAL FINDINGS: Immunophenotypic analyses of differentiating hESC identified a subpopulation of cells expressing high levels of CD41a that expressed other markers associated with the Mk lineage, including CD110, CD42b and CD61. Differentiated cells were sorted on the basis of their expression of CD41a, CD34 and CD45 and assessed for Mk colony formation, expression of myeloid and Mk genes and ability to endoreplicate DNA. In a collagen-based colony assay, the CD41a⁺ cells sorted from these differentiation cultures produced 100-800 Mk progenitors at day 13 and 25-160 Mk progenitors at day 20 of differentiation per 100,000 cells assayed. Differentiated Mk cells produced platelet-like particles which expressed CD42b and were activated by ADP, similar to platelets generated from precursors in cord blood. These studies were complemented by real time PCR analyses showing that subsets of cells enriched for CD41a⁺ Mk precursors expressed high levels of Mk associated genes such as PF4 and MPL. Conversely, high levels of myeloid and erythroid related transcripts, such as GATA1, TAL1/SCL and PU.1, were detected in sorted fractions containing CD34⁺ and CD45⁺ cells. CONCLUSIONS: We describe a serum- and feeder-free culture system that enabled the generation of Mk progenitors from human embryonic stem cells. These cells formed colonies that included differentiated Mks that fragmented to form platelet-like particles. This protocol represents an important step towards the generation of human platelets for therapeutic use.

  10. A simple and efficient feeder-free culture system to up-scale iPSCs on polymeric material surface for use in 3D bioprinting.

    Science.gov (United States)

    Wong, Chui-Wei; Chen, You-Tzung; Chien, Chung-Liang; Yu, Tien-Yu; Rwei, Syang-Peng; Hsu, Shan-Hui

    2018-01-01

    The 3D bioprinting and cell/tissue printing techniques open new possibilities for future applications. To facilitate the 3D bioprinting process, a large amount of living cells are required. Induced pluripotent stem cells (iPSCs) represent a promising cell source for bioprinting. However, the maintenance and expansion of undifferentiated iPSCs are expensive and time consuming. Therefore, in this study a culture method to obtain a sufficient amount of healthy and undifferentiated iPSCs in a short-term period was established. The iPSCs could be passaged for twice on tissue culture polystyrene (TCPS) dish with the conditional medium and could adapt to the feeder-free environment. Feeder-free dishes were further prepared from chitosan, chitosan-hyaluronan, silk fibroin, and polyurethane (PU1 and PU2) two-dimensional substrates. The iPSCs cultured on the chitosan substrates showed a higher proliferation rate without losing the stemness feature. Among the different materials, PU2 could be prepared as a thermoresponsive hydrogel, which was a potential ink for 3D bioprinting. The iPSCs cultured on PU2 substrates well survived when further embedded in PU2 hydrogel. Moreover, PU2 hydrogel printed with iPSCs remained structural integrity. The use of PU2 hydrogel to embed iPSCs reduced the injury to iPSCs by shear stress. These results indicate that iPSCs could be expanded on chitosan or PU2 membranes without the feeder layer and then printed in PU2 hydrogel. The combination of these steps could offer a new possibility for future applications of iPSC-based 3D bioprinting in tissue engineering. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Trophodynamics of inorganic pollutants in a wide-range feeder: The relevance of dietary inputs and biomagnification in the Yellow-legged gull (Larus michahellis)

    International Nuclear Information System (INIS)

    Ramos, Raül; Ramírez, Francisco; Jover, Lluís

    2013-01-01

    The suitability of sentinel species to monitor environmental pollution is often hampered by an insufficient knowledge on pollutant trophodynamics. We simultaneously evaluated the influence of individuals' trophic position (as revealed by δ 15 N values) and dietary exploitation of particular systems (using δ 13 C and δ 34 S as proxies) on inorganic pollutant concentrations measured on fledglings' feathers of a wide-range feeder, the Yellow-legged Gull (Larus michahellis), sampled at four locations throughout the Western Mediterranean. Concentrations of total Hg and Se in fledgling feathers (2.43 ± 1.30 and 1.16 ± 0.43 μg/g, respectively) were under the threshold points for deleterious effects on seabirds. On the contrary, alarming Pb concentrations were found in one colony (mean: 1.57 ± 2.46 μg/g, range: 0.16–12.13). With the exception of Pb, pollutant concentrations were positively influenced by consumption of marine resources (as suggested by the positive relationship with δ 34 S values), whereas trophic position played a minor role in determining pollutant body burdens. - Graphical abstract: Individual feeding behaviours in wide-range feeders may represent unavoidable knowledge for an appropriate understanding of contaminant acquisition, adding complexity to the study of the dynamic of contaminants throughout food chains. In this case study, pollutant body burden of Yellow-legged gull (Larus michahellis) chicks was highly influenced by dietary exposure, whereas the influence of trophic position was relatively low. Display Omitted Highlights: ► Diet origin (δ 34 S) and trophic position (δ 15 N) were tested relative to Hg, Se, and Pb levels. ► Hg and Se concentrations in gull feathers were highly influenced by δ 34 S signatures. ► Exploited habitat influenced pollutant levels to a greater extent than trophic position. ► Biomagnification processes contribute less to contamination exposure in wide-range feeders. - Pollutant body burden of a wide

  12. Human amniotic epithelial cell feeder layers maintain human iPS cell pluripotency via inhibited endogenous microRNA-145 and increased Sox2 expression

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Te, E-mail: liute79@yahoo.com [School of Environmental Science and Engineering, Donghua University, Shanghai 201620 (China); Shanghai Geriatric Institute of Chinese Medicine, Shanghai 200031 (China); Cheng, Weiwei [International Peace Maternity and Child Health Hospital, Shanghai Jiaotong University, Shanghai 200030 (China); Huang, Yongyi [Laboratoire PROTEE, Batiment R, Universite du Sud Toulon-Var, 83957 LA GARDE Cedex (France); Huang, Qin; Jiang, Lizhen [Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031 (China); Guo, Lihe, E-mail: liute79@yahoo.com [Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031 (China)

    2012-02-15

    Currently, human induced pluripotent stem (iPS) cells were generated from patient or disease-specific sources and share the same key properties as embryonic stem cells. This makes them attractive for personalized medicine, drug screens or cellular therapy. Long-term cultivation and maintenance of normal iPS cells in an undifferentiated self-renewing state are a major challenge. Our previous studies have shown that human amniotic epithelial cells (HuAECs) could provide a good source of feeder cells for mouse and human embryonic stem cells, or spermatogonial stem cells, but the mechanism for this is unknown. Here, we examined the effect of endogenous microRNA-145 regulation on Sox2 expression in human iPS cells by HuAECs feeder cells regulation, and in turn on human iPS cells pluripotency. We found that human IPS cells transfected with a microRNA-145 mutant expressed Sox2 at high levels, allowing iPS to maintain a high level of AP activity in long-term culture and form teratomas in SCID mice. Expression of stem cell markers was increased in iPS transfected with the microRNA-145 mutant, compared with iPS was transfected with microRNA-145. Besides, the expression of Drosha proteins of the microRNA-processor complex, required for the generation of precursor pre-miRNA, was significantly increased in human iPS cells cultured on MEF but not on HuAECs. Taken together, these results suggest that endogenous Sox2 expression may be regulated by microRNA-145 in human iPS cells with HuAECs feeder cells, and Sox2 is a crucial component required for maintenance of them in an undifferentiated, proliferative state capable of self-renewal. Highlights: Black-Right-Pointing-Pointer microRNA-145 inhibits Sox2 expression in human iPS cells. Black-Right-Pointing-Pointer microRNA-145 suppresses the self-renewal and pluripotency of human iPS cells. Black-Right-Pointing-Pointer HuAECs regulate expression of microRNA-145 and Sox2 in human iPS cells. Black-Right-Pointing-Pointer HuAECs feeder

  13. Human amniotic epithelial cell feeder layers maintain human iPS cell pluripotency via inhibited endogenous microRNA-145 and increased Sox2 expression

    International Nuclear Information System (INIS)

    Liu, Te; Cheng, Weiwei; Huang, Yongyi; Huang, Qin; Jiang, Lizhen; Guo, Lihe

    2012-01-01

    Currently, human induced pluripotent stem (iPS) cells were generated from patient or disease-specific sources and share the same key properties as embryonic stem cells. This makes them attractive for personalized medicine, drug screens or cellular therapy. Long-term cultivation and maintenance of normal iPS cells in an undifferentiated self-renewing state are a major challenge. Our previous studies have shown that human amniotic epithelial cells (HuAECs) could provide a good source of feeder cells for mouse and human embryonic stem cells, or spermatogonial stem cells, but the mechanism for this is unknown. Here, we examined the effect of endogenous microRNA-145 regulation on Sox2 expression in human iPS cells by HuAECs feeder cells regulation, and in turn on human iPS cells pluripotency. We found that human IPS cells transfected with a microRNA-145 mutant expressed Sox2 at high levels, allowing iPS to maintain a high level of AP activity in long-term culture and form teratomas in SCID mice. Expression of stem cell markers was increased in iPS transfected with the microRNA-145 mutant, compared with iPS was transfected with microRNA-145. Besides, the expression of Drosha proteins of the microRNA-processor complex, required for the generation of precursor pre-miRNA, was significantly increased in human iPS cells cultured on MEF but not on HuAECs. Taken together, these results suggest that endogenous Sox2 expression may be regulated by microRNA-145 in human iPS cells with HuAECs feeder cells, and Sox2 is a crucial component required for maintenance of them in an undifferentiated, proliferative state capable of self-renewal. Highlights: ► microRNA-145 inhibits Sox2 expression in human iPS cells. ► microRNA-145 suppresses the self-renewal and pluripotency of human iPS cells. ► HuAECs regulate expression of microRNA-145 and Sox2 in human iPS cells. ► HuAECs feeder layers maintain human iPS cells pluripotency. ► HuAECs negatively regulates the synthesis of

  14. Belt deviation and its solution of belt weighing feeder machine%皮带称重绐料机皮带跑偏问题殁对策

    Institute of Scientific and Technical Information of China (English)

    张荣轩

    2012-01-01

    This article analyzes the reasons of common belt deviation problems during the using of belt weighing feeder machine, and combining practical work experience, proposed its solutions.%本文就皮带称重给料机在使用过程中常见的皮带跑偏问题进行了原因分析,并结合本人多年的工作实践经验,提出其相应的解决办法。

  15. Quantitative control of belt weighing feeder quick loading system%定量控制皮带称重式给料机快速装车系统

    Institute of Scientific and Technical Information of China (English)

    张荣轩

    2012-01-01

    This paper introduces a kind of belt weighing feeder quantitative control technology, which realizes the bulk material rapid loading design and widely used in coal metallurgy, chemical industry, building materials industry.%本文介绍了一种对皮带称重式给料机进行定量控制技术,实现散状物料快速装车的设计方案,广泛适用于煤炭、冶金、化工和建材等行业。

  16. Weaning age of calves fed a high milk allowance by automated feeders: effects on feed, water, and energy intake, behavioral signs of hunger, and weight gains.

    Science.gov (United States)

    de Passillé, A M; Borderas, T F; Rushen, J

    2011-03-01

    Dairy calves are increasingly fed large volumes of milk, which reduces feeding motivation and improves weight gain. However, calves often show signs of hunger and lose weight when weaned off milk due to low starter intake. We examined whether delaying the age at weaning would reduce responses to weaning. Calves were raised in groups of 9 and fed milk, starter, hay, and water with automated feeders. In each group, 3 calves were randomly assigned to 1 of 3 treatments: (1) low-milk, early-weaned: fed 6 L/d of milk and weaned at 47 d of age; (2) high-milk early-weaned: fed 12 L/d of milk and weaned at 47 d; (3) high-milk later-weaned: fed 12 L/d of milk and weaned at 89 d of age. Milk, starter, and hay intakes were recorded daily and digestible energy (DE) intake estimated. Feeder visits were recorded. Before weaning, the high-milk calves drank more milk, ate less starter and hay, but had higher DE intakes, gained more weight, and made fewer visits to the milk feeder than the low-milk, early-weaned calves. During and immediately after weaning, the high-fed, early-weaned calves ate less starter and hay, had lower DE intakes, and gained less weight than the low-milk, early-weaned calves and lost their body weight advantage 7 d after weaning. During and immediately after weaning, the high-milk, later-weaned calves ate more starter and hay and had higher DE intakes, higher weight gains, and made fewer visits to the milk feeder than the high-milk, early-weaned calves. They were still heavier than the low-milk, early-weaned calves 18 d after weaning. Delaying the age at which calves are weaned off milk reduces the drop in energy intake and behavioral signs of hunger that result from weaning. Copyright © 2011 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  17. Cost Behavior

    DEFF Research Database (Denmark)

    Hoffmann, Kira

    The objective of this dissertation is to investigate determinants and consequences of asymmetric cost behavior. Asymmetric cost behavior arises if the change in costs is different for increases in activity compared to equivalent decreases in activity. In this case, costs are termed “sticky......” if the change is less when activity falls than when activity rises, whereas costs are termed “anti-sticky” if the change is more when activity falls than when activity rises. Understanding such cost behavior is especially relevant for decision-makers and financial analysts that rely on accurate cost information...... to facilitate resource planning and earnings forecasting. As such, this dissertation relates to the topic of firm profitability and the interpretation of cost variability. The dissertation consists of three parts that are written in the form of separate academic papers. The following section briefly summarizes...

  18. Robust and highly-efficient differentiation of functional monocytic cells from human pluripotent stem cells under serum- and feeder cell-free conditions.

    Directory of Open Access Journals (Sweden)

    Masakatsu D Yanagimachi

    Full Text Available Monocytic lineage cells (monocytes, macrophages and dendritic cells play important roles in immune responses and are involved in various pathological conditions. The development of monocytic cells from human embryonic stem cells (ESCs and induced pluripotent stem cells (iPSCs is of particular interest because it provides an unlimited cell source for clinical application and basic research on disease pathology. Although the methods for monocytic cell differentiation from ESCs/iPSCs using embryonic body or feeder co-culture systems have already been established, these methods depend on the use of xenogeneic materials and, therefore, have a relatively poor-reproducibility. Here, we established a robust and highly-efficient method to differentiate functional monocytic cells from ESCs/iPSCs under serum- and feeder cell-free conditions. This method produced 1.3 × 10(6 ± 0.3 × 10(6 floating monocytes from approximately 30 clusters of ESCs/iPSCs 5-6 times per course of differentiation. Such monocytes could be differentiated into functional macrophages and dendritic cells. This method should be useful for regenerative medicine, disease-specific iPSC studies and drug discovery.

  19. Identification of pectenotoxins in plankton, filter feeders, and isolated cells of a Dinophysis acuminata with an atypical toxin profile, from Chile.

    Science.gov (United States)

    Blanco, Juan; Alvarez, Gonzalo; Uribe, Eduardo

    2007-04-01

    A bloom of Dinophysis acuminata produced, in autumn of 2005, a closure of the scallop harvesting in Bahía Inglesa, in the Chilean III region. Isolated cells of this Dinophysis species were shown to contain 180 pg cell(-1) of pectenotoxin 2 but neither okadaic acid nor any of its analogs or derivatives (at least at a detectable level). Examination of plankton and filter-feeder samples covering an area of ca. 350 km, from the location where the toxicity was recorded to Bahía Tongoy, showed that the unique toxin profile found in the first bloom was widespread over that part of Chile and persisted for months. The analysis were carried out by HPLC-ESI-MS using positive ionization mode, with a detection limit below 2 ng of OA mL(-1) of methanolic extract. This is the first report of the presence of pectenotoxins in the plankton of the Pacific coast of America and in the studied filter feeders. This is also the first report of a Dinophysis species containing pectenotoxins and not any toxin of the okadaic acid group.

  20. Human amniotic epithelial cell feeder layers maintain mouse embryonic stem cell pluripotency via epigenetic regulation of the c-Myc promoter.

    Science.gov (United States)

    Liu, Te; Cheng, Weiwei; Liu, Tianjin; Guo, Lihe; Huang, Qin; Jiang, Lizhen; Du, Xiling; Xu, Fuhui; Liu, Zhixue; Lai, Dongmei

    2010-02-01

    Mouse embryonic stem cells (ESCs) are typically cultured on a feeder layer of mouse embryonic fibroblasts (MEFs), with leukemia inhibitory factor (LIF) added to maintain them in an undifferentiated state. We have previously shown that human amniotic epithelial cells (hAECs) can be used as feeder cells to maintain mouse ESC pluripotency, but the mechanism for this is unknown. In the present study, we found that CpG islands 5' of the c-Myc gene remain hypomethylated in mouse ESCs cultured on hAECs. In addition, levels of acetylation of histone H3 and trimethylation of histone H3K4 in the c-Myc gene promoter were higher in ES cells cultured on hAECs than those in ES cells cultured on MEFs. These data suggested that hAECs can alter mouse ESC gene expression via epigenetic modification of c-Myc, providing a possible mechanism for the hAEC-induced maintenance of ESCs in an undifferentiated state.

  1. Research, Development and Demonstration of Peak Load Reduction on Distribution Feeders Using Distributed Energy Resources for the City of Fort Collins

    Energy Technology Data Exchange (ETDEWEB)

    Sumner, Dennis [City of Fort Collins Utilities, CO (United States); Vosburg, Tom [City of Fort Collins Utilities, CO (United States); Brunner, Steve [Brendle Group, Fort Collins, CO (United States); Gates, Judy [Woodward, Inc., Fort Collins, CO (United States); Howard, Nathan [Spirae, Inc., Fort Collins, CO (United States); Merton, Andrew [Spirae, Inc., Fort Collins, CO (United States); Wright, Don [Spirae, Inc., Fort Collins, CO (United States); Birlingmair, Doug [Spirae, Inc., Fort Collins, CO (United States)

    2015-10-01

    This project titled “Research, Development and Demonstration of Peak Load Reduction on Distribution Feeders Using Distributed Energy Resources for the City of Fort Collins” evolved in response to the Department of Energy’s (DOE) Funding Opportunity Announcement (FOA) Number DE-PS26-07NT43119. Also referred to as the Fort Collins Renewable and Distributed System Integration (RDSI) Project, the effort was undertaken by a diverse group of local government, higher education and business organizations; and was driven by three overarching goals: I. Fulfill the requirements of the DOE FOA’s Area of Interest 2: Renewable and Distributed System Integration; most notably, to demonstrate the ability to reduce electric system distribution feeder peak load by 15% or more through the coordinated use of Distributed Energy Resources (DER). II. Advance the expertise, technologies and infrastructure necessary to support the long term vision of the Fort Collins Zero Energy District (FortZED) and move towards creating a zero energy district in the Fort Collins “Old Town” area. III. Further the goals of the City of Fort Collins Energy Policy, including the development of a Smart Grid-enabled distribution system in Fort Collins, expanded use of renewable energy, increased energy conservation, and peak load reduction. Through the collaborative efforts of the partner organizations, the Fort Collins RDSI project was successful in achieving all three of these goals. This report is organized into two distinct sections corresponding to the two phases of the project: • Part 1: Feeder Peak Load Reduction and the FortZED Initiative. • Part 2: Forming and Operating Utility Microgrids and Managing Load and Production Variability The original project scope addressed the Part 1 feeder peak load reduction. That work took place from 2009 through 2011 and was largely complete when the project scope was amended to include a demonstration of microgrid operations. While leveraging the

  2. Teacher Costs

    OpenAIRE

    DINIS MOTA DA COSTA PATRICIA; DE SOUSA LOBO BORGES DE ARAUJO LUISA

    2015-01-01

    The purpose of this technical brief is to assess current methodologies for the collection and calculation of teacher costs in European Union (EU) Member States in view of improving data series and indicators related to teacher salaries and teacher costs. To this end, CRELL compares the Eurydice collection on teacher salaries with the similar Organisation for Economic Co-operation and Development (OECD) data collection and calculates teacher costs based on the methodology established by Statis...

  3. Rehabilitation costs

    Energy Technology Data Exchange (ETDEWEB)

    Kubo, Arthur S [BDM Corp., VA (United States); [Bikini Atoll Rehabilitation Committee, Berkeley, CA (United States)

    1986-07-01

    The costs of radioactivity contamination control and other matters relating to the resettlement of Bikin atoll were reviewed for Bikini Atoll Rehabilitation Committee by a panel of engineers which met in Berkeley, California on January 22-24, 1986. This Appendix presents the cost estimates.

  4. Rehabilitation costs

    International Nuclear Information System (INIS)

    Kubo, Arthur S.

    1986-01-01

    The costs of radioactivity contamination control and other matters relating to the resettlement of Bikin atoll were reviewed for Bikini Atoll Rehabilitation Committee by a panel of engineers which met in Berkeley, California on January 22-24, 1986. This Appendix presents the cost estimates

  5. Cost considerations

    NARCIS (Netherlands)

    Michiel Ras; Debbie Verbeek-Oudijk; Evelien Eggink

    2013-01-01

    Original title: Lasten onder de loep The Dutch government spends almost 7 billion euros  each year on care for people with intellectual disabilities, and these costs are rising steadily. This report analyses what underlies the increase in costs that occurred between 2007 and 2011. Was

  6. Troubleshooting Costs

    Science.gov (United States)

    Kornacki, Jeffrey L.

    Seventy-six million cases of foodborne disease occur each year in the United States alone. Medical and lost productivity costs of the most common pathogens are estimated to be 5.6-9.4 billion. Product recalls, whether from foodborne illness or spoilage, result in added costs to manufacturers in a variety of ways. These may include expenses associated with lawsuits from real or allegedly stricken individuals and lawsuits from shorted customers. Other costs include those associated with efforts involved in finding the source of the contamination and eliminating it and include time when lines are shut down and therefore non-productive, additional non-routine testing, consultant fees, time and personnel required to overhaul the entire food safety system, lost market share to competitors, and the cost associated with redesign of the factory and redesign or acquisition of more hygienic equipment. The cost associated with an effective quality assurance plan is well worth the effort to prevent the situations described.

  7. Cost comparisons

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    How much does the LHC cost? And how much does this represent in other currencies? Below we present a table showing some comparisons with the cost of other projects. Looking at the figures, you will see that the cost of the LHC can be likened to that of three skyscrapers, or two seasons of Formula 1 racing! One year's budget of a single large F1 team is comparable to the entire materials cost of the ATLAS or CMS experiments.   Please note that all the figures are rounded for ease of reading.    CHF € $   LHC 4.6 billions 3 billions  4 billions   Space Shuttle Endeavour (NASA) 1.9 billion 1.3 billion 1.7 billion   Hubble Space Telescope (cost at launch – NASA/...

  8. A feeder- and xeno-free human induced pluripotent stem cell line obtained from primary human dermal fibroblasts with epigenetic repression of reprogramming factors expression: GPCCi001-A

    Directory of Open Access Journals (Sweden)

    Michał Stefan Lach

    2017-04-01

    Full Text Available The primary human dermal fibroblasts (PHDFs from breast cancer patient were obtained to generate the human induced pluripotent stem cell line GPCCi001-A via lentiviral transfection. Thus, a modified EF1a-hSTEMCCA-loxP with tetO operator which regulates transgene expression was used. This method takes advantage of epigenetic regulation of transcription and allows for stable silencing of the reprogramming factors in obtained hiPS cells. To increase the potential utility of hiPSCs for clinical applications, they were adapted to feeder- and xeno-free conditions. The pluripotency of GPCCi001-A cell line and ability to differentiate into three germ layers was confirmed.

  9. A defined, feeder-free, serum-free system to generate in vitro hematopoietic progenitors and differentiated blood cells from hESCs and hiPSCs.

    Directory of Open Access Journals (Sweden)

    Giorgia Salvagiotto

    2011-03-01

    Full Text Available Human ESC and iPSC are an attractive source of cells of high quantity and purity to be used to elucidate early human development processes, for drug discovery, and in clinical cell therapy applications. To efficiently differentiate pluripotent cells into a pure population of hematopoietic progenitors we have developed a new 2-dimensional, defined and highly efficient protocol that avoids the use of feeder cells, serum or embryoid body formation. Here we showed that a single matrix protein in combination with growth factors and a hypoxic environment is sufficient to generate from pluripotent cells hematopoietic progenitors capable of differentiating further in mature cell types of different lineages of the blood system. We tested the differentiation method using hESCs and 9 iPSC lines generated from different tissues. These data indicate the robustness of the protocol providing a valuable tool for the generation of clinical-grade hematopoietic cells from pluripotent cells.

  10. Comparative bioaccumulation of trace metals using six filter feeder organisms in a coastal lagoon ecosystem (of the central-east Gulf of California).

    Science.gov (United States)

    Jara-Marini, M E; Tapia-Alcaraz, J N; Dumer-Gutiérrez, J A; García-Rico, L; García-Hernández, J; Páez-Osuna, F

    2013-02-01

    The Tobari Lagoon, located in the central-east coast of the Gulf of California, receives effluents from the Yaqui Valley, one of the most extensive agricultural areas of México. The Tobari Lagoon also receives effluents from nearby shrimp farms and untreated municipal sewage. Surface sediment samples and six different species of filter feeders (Crassostrea corteziensis, Crassostrea gigas, Chione gnidia, Anadara tuberculosa, Chione fluctifraga, and Fistulobalanus dentivarians) were collected during the dry and the rainy seasons and analyzed to determine concentrations of cadmium (Cd), copper (Cu), mercury (Hg), lead (Pb), and zinc (Zn). Seasonal variations in metal concentrations in sediment were evident, especially for Cd, Cu, Hg, and Zn. The total and bioavailable concentrations of the five metals are not elevated in comparison to other areas around the world. The percentages of bioavailable respect to total concentrations of the metals varied from 0.6 % in Hg to 50.2 % for Cu. In the organisms, Hg showed the lowest concentrations (ranged from 0.22 to 0.65 μg/g) while Zn showed the highest (ranged from 36.6 to 1,702 μg/g). Linear correlations between the levels of Cu, Pb, and Zn in the soft tissues of C. fluctifraga and C. gnidia, and A. tuberculosa and C. gnidia were found. Seasonal and interspecies variations in the metal levels in filter feeders were found; F. dentivarians, C. corteziensis, and C. gigas exhibited the highest levels, could be used as biomonitors of metals contamination in this area.

  11. Easy xeno-free and feeder-free method for isolating and growing limbal stromal and epithelial stem cells of the human cornea.

    Directory of Open Access Journals (Sweden)

    Djida Ghoubay-Benallaoua

    Full Text Available Epithelial and stromal stem cells are required to maintain corneal transparency. The aim of the study was to develop a new method to isolate and grow both corneal stromal (SSC and epithelial limbal (LSC stem cells from small human limbal biopsies under culture conditions in accordance with safety requirements mandatory for clinical use in humans. Superficial limbal explants were retrieved from human donor corneo-scleral rims. Human limbal cells were dissociated by digestion with collagenase A, either after epithelial scraping or with no scraping. Isolated cells were cultured with Essential 8 medium (E8, E8 supplemented with EGF (E8+ or Green's medium with 3T3 feeder-layers. Cells were characterized by immunostaining, RT-qPCR, colony forming efficiency, sphere formation, population doubling, second harmonic generation microscopy and differentiation potentials. LSC were obtained from unscraped explants in E8, E8+ and Green's media and were characterized by colony formation and expression of PAX6, ΔNP63α, Bmi1, ABCG2, SOX9, CK14, CK15 and vimentin, with a few cells positive for CK3. LSC underwent 28 population doublings still forming colonies. SSC were obtained from both scraped and unscraped explants in E8 and E8+ media and were characterized by sphere formation, expression of PAX6, SOX2, BMI1, NESTIN, ABCG2, KERATOCAN, VIMENTIN, SOX9, SOX10 and HNK1, production of collagen fibrils and differentiation into keratocytes, fibroblasts, myofibroblasts, neurons, adipocytes, chondrocytes and osteocytes. SSC underwent 48 population doublings still forming spheres, Thus, this new method allows both SSC and LSC to be isolated from small superficial limbal biopsies and to be primary cultured in feeder-free and xeno-free conditions, which will be useful for clinical purposes.

  12. Comparison of the Ex Vivo Expansion of UCB-Derived CD34+ in 3D DBM/MBA Scaffolds with USSC as a Feeder Layer.

    Science.gov (United States)

    Sadat Hashemi, Zahra; Forouzandeh Moghadam, Mahdi; Soleimani, Masoud

    2013-10-01

    Ex vivo expansion of hematopoitic stem cells is an alternative way to increase umbilical cord blood (UCB)-CD34+ cells for bone marrow transplantation. For this purpose demineralized bone matrix (DBM) and mineralized bone allograft (MBA) as two scaffolds based on bone matrix and stem cell niche, were simultaneously used to enhance the effect of human mesenchymal progenitor cells (MPCs) - unrestricted somatic stem cells (USSCs) - as a feeder layer. USSCs were isolated and characterized by morphological and immunological analysis then seeded on both scaffolds as a feeder layer. UCB-CD34(+) were isolated by MACS method and were co-culture expanded by USSC in 3D and 2D environments. After 3 weeks expansion, cells were counted and were assessed by karyotype, flow cytometry, clonogenic activity, and long-term culture-initiating cells (LTC-IC). Co-culture expansion in DBM and MBA was 29.22-fold and 27.77-fold, no significant differences in colony and LTC-IC were obtained. Maximum number of colonies belonged to the day 14 with the 73% CFU-GM (Colony Forming Unit- Granulocyte/Macrophage) in contrast to the day 0 which was BFU-E/CFU-E (Burst/Colony Forming Unit-Erythroid). Flow cytometry indicated that the percentage of CD34+ marker was decreased in USSC co-culture and the highest percentage was observed in simple 2D culture. Because of acid extraction in the DBM production process, mineral materials were removed and the protein background that was more flexible was presented. Therefore these results suggest that USSC-DBM can be a suitable ex vivo mimicry niche by intensifying of surface/volume ratio and supporting the stem cell differentiation and expansion.

  13. 47 CFR 25.250 - Sharing between NGSO MSS Feeder links Earth Stations in the 19.3-19.7 GHz and 29.1-29.5 GHz Bands.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Sharing between NGSO MSS Feeder links Earth Stations in the 19.3-19.7 GHz and 29.1-29.5 GHz Bands. 25.250 Section 25.250 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES SATELLITE COMMUNICATIONS Technical Standards § 25...

  14. Practice on Protection and Improvement of Withstand Voltage Weighing Belt Coal Feeder%耐压称重式皮带给煤机保护改进实践

    Institute of Scientific and Technical Information of China (English)

    王良

    2016-01-01

    This paper introduces the traits of withstand voltage weighing belt coal feeder. According to the modification and practice of parameters of the frequency converter, when there is a malfunction, the automatic recovery of the frequency converter of coal feeder can be achieved. The reliability of the coal feeder ’s operation will be improved, and the effects of the accident power supply perturbation on the coal feeder can be eliminated. Eventually, the safety and stability of the boilers can be guaranteed.%文章介绍了耐压称重式皮带给煤机的特性,通过对变频器参数修改实践,实现给煤机变频器故障保护自动恢复,提高给煤机运行的可靠性,消除电源意外扰动对给煤机的影响,保障锅炉安全持续稳定运行。

  15. Fitness cost

    DEFF Research Database (Denmark)

    Nielsen, Karen L.; Pedersen, Thomas M.; Udekwu, Klas I.

    2012-01-01

    phage types, predominantly only penicillin resistant. We investigated whether isolates of this epidemic were associated with a fitness cost, and we employed a mathematical model to ask whether these fitness costs could have led to the observed reduction in frequency. Bacteraemia isolates of S. aureus...... from Denmark have been stored since 1957. We chose 40 S. aureus isolates belonging to phage complex 83A, clonal complex 8 based on spa type, ranging in time of isolation from 1957 to 1980 and with varyous antibiograms, including both methicillin-resistant and -susceptible isolates. The relative fitness...... of each isolate was determined in a growth competition assay with a reference isolate. Significant fitness costs of 215 were determined for the MRSA isolates studied. There was a significant negative correlation between number of antibiotic resistances and relative fitness. Multiple regression analysis...

  16. (Super Variable Costing-Throughput Costing)

    OpenAIRE

    Çakıcı, Cemal

    2006-01-01

    (Super Variable Costing-Throughput Costing) The aim of this study is to explain the super-variable costing method which is a new subject in cost and management accounting and to show it’s working practicly.Shortly, super-variable costing can be defined as a costing method which is use only direct material costs in calculate of product costs and treats all costs except these (direct labor and overhead) as periad costs or operating costs.By using super-variable costing method, product costs ar...

  17. Multi-objective stochastic distribution feeder reconfiguration problem considering hydrogen and thermal energy production by fuel cell power plants

    International Nuclear Information System (INIS)

    Niknam, Taher; Kavousi Fard, Abdollah; Baziar, Aliasghar

    2012-01-01

    This paper assesses the operation and management of electrical energy, hydrogen production and thermal load supplement by the Fuel Cell Power Plants (FCPP) in the distribution systems with regard to the uncertainties which exist in the load demand as well as the price of buying natural gas for FCPPs, fuel cost for residential loads, tariff for purchasing electricity, tariff for selling electricity, hydrogen selling price, operation and maintenance cost and the price of purchasing power from the grid. Therefore, a new modified multi-objective optimization algorithm called Teacher-Learning Algorithm (TLA) is proposed to integrate the optimal operation management of Proton Exchange Membrane FCPPs (PEM-FCPPs) and the optimal configuration of the system through an economic model of the PEM-FCPP. In order to improve the total ability of TLA for global search and exploration, a new modification process is suggested such that the algorithm will search the total search space globally. Also, regarding the uncertainties of the new complicated power systems, in this paper for the first time, the DFR problem is investigated in a stochastic environment by the use of probabilistic load flow technique based on Point Estimate Method (PEM). In order to see the feasibility and the superiority of the proposed method, a standard test system is investigated as the case study. The simulation results are investigated in four different scenarios to show the effect of hydrogen production and thermal recovery more evidently. -- Highlights: ► Present an economical and thermal modeling of PEM-FCPPs. ► Present an approach for optimal operation of PEM-FCPPs in a stochastic environment. ► Consider benefits of thermal recovery and Hydrogen production for PEM-FCPPs. ► Present several scenarios for management of PEM-FCPPs.

  18. Critical evaluation of gamma-irradiated serum used as feeder in the culture and demonstration of putative nanobacteria and calcifying nanoparticles.

    Directory of Open Access Journals (Sweden)

    Jan Martel

    used as feeder. Thus, the NB/CNP described in the literature clearly bear hybrid protein compositions belonging to different species. We conclude that there is no basis to justify the use of gamma-FBS as a feeder for the growth and demonstration of NB/CNP or any NB-like particles in culture. Moreover, our results call into question the validity of the entire body of literature accumulated to date on NB and CNP.

  19. Effects of temperament and acclimation to handling on feedlot performance of Bos taurus feeder cattle originated from a rangeland-based cow-calf system.

    Science.gov (United States)

    Francisco, C L; Cooke, R F; Marques, R S; Mills, R R; Bohnert, D W

    2012-12-01

    Two experiments evaluated the effects of temperament and acclimation to handling on performance of Angus × Hereford feeder cattle reared in extensive rangeland systems until weaning. In Exp. 1, 200 calves (n = 97 for yr 1; n = 103 for yr 2) were evaluated for temperament at weaning (average age ± SE = 152 ± 1 d) by chute score and exit velocity. Chute score was assessed on a 5-point scale according to behavior during chute restraining. Exit score was calculated by dividing exit velocity into quintiles and assigning calves a score from 1 (slowest) to 5 (fastest). A temperament score was calculated for each calf by averaging chute and exit scores. Calf temperament was classified according to temperament score as adequate (≤3) or excitable (>3). After weaning, calves were assigned to a 40-d preconditioning followed by growing (139 d) and finishing (117 d) phases until slaughter. Weaning BW was decreased (P = 0.04) in excitable calves compared with adequate calves. No differences were detected (P ≥ 0.21) for ADG during preconditioning, growing, and finishing phases; hence, excitable calves tended (P = 0.09) to have decreased HCW compared with adequate calves. In Exp. 2, 60 steers (initial age ± SE = 198 ± 2 d) were weighed and evaluated for temperament score 35 d after weaning (d -29). On d -28, steers were ranked by these variables and assigned to receive an acclimation treatment or not (control). Acclimated steers were processed through a handling facility twice weekly for 4 wk (d -28 to -1) whereas control steers remained undisturbed on pasture. On d 0, all steers were transported for 24 h and returned to the research facility (d 1). On arrival, steers were ranked by BW within treatment and randomly assigned to 20 feedlot pens for a 28-d feedlot receiving period. Acclimated steers had decreased temperament score and plasma cortisol compared with controls on d 0 (P = 0.02). During feedlot receiving, acclimated steers had decreased ADG (P < 0.01) and G:F (P

  20. Cost restructuring

    International Nuclear Information System (INIS)

    Schmidt, J.A.

    1991-01-01

    This paper reports on the cost restructuring of the petroleum industry. This current decade is likely to be one of the most challenging for the petroleum industry. Though petroleum remains among the world's biggest businesses, news of consolidations, restructuring, and layoffs permeates the oil patch from the Gulf of Mexico to the Arctic Isles. The recessionary economy has accelerated these changes, particularly in the upstream sector. Today, even the best-managed companies are transforming their cost structures, and companies that fail to do likewise probably won't survive as independent companies. Indeed, significant consolidation took place during the 1980s. More consolidations can be expected in this decade for companies that do not adapt to the economic realities of the mature business

  1. Role of Air Cargo and Road Feeder Services for Regional Airports – Case Studies from the Baltic Sea Region

    Directory of Open Access Journals (Sweden)

    Beifert Anatoli

    2016-06-01

    Full Text Available Although airports play an important role the global and European economies, according to the new guidelines of the EU Commission on the new state aid rules for a competitive aviation industry (EC, 2014, it will be more difficult for unprofitable airports, to get financial public subsidies in the future. The Commission noted that the majority of regional airports experience severe problems to cover their operative costs, resulting from among other things from overlapping of airports’ catchment areas. The main objective of the above mentioned measures is not to close the regional airports, but to motivate them to operate on cost efficient, profitable and more flexible basis, stating however that and that the most inefficient airports will be still closed. In order face upcoming challenges, the regional airports shall reconsider their future development plans. Traditionally, the airports including small and regional airports focus on the passenger traffic and thus, the possible benefits and opportunities of the air cargo market are totally underestimated or even completely ignored. Most regional airports in the Baltic Sea region act totally isolated and do not have a clear picture of the current situation on the international air cargo market today, its future perspectives and sustainable development plans remain basically hidden. There are some examples when trying to meet the market demand, the regional airports have made huge, but unfortunately unjustified investments, e.g. improving airport infrastructure, runways, etc. However, the airports’ infrastructural investments alone cannot fulfil the expected “remedy” role for the airports’ sustainability. This paper aims at investigating the positioning and the role of the regional airports in the current hub-and-spoke network, focusing on the relevance and potential of the air cargo sector for the regional airports development. The optional freight value proposition for the development of

  2. Feeder and post Deccan Trap dyke activities in the northern slope of the Satpura Mountain: Evidence from new 40Ar-39Ar ages

    Directory of Open Access Journals (Sweden)

    J.P. Shrivastava

    2017-05-01

    Full Text Available We present new 40Ar-39Ar plagioclase crystallization ages from the dykes exposed at the northern slope of the Satpura Mountain range near Betul-Jabalpur-Pachmarhi area, ∼800 km NE of the Western Ghats escarpment. Among the two plateau ages, the first age of 66.56 ± 0.42 Ma from a dyke near Mohpani village represents its crystallization age which is either slightly older or contemporaneous with the nearby Mandla lava flows (63–65 Ma. We suggest that the Mohpani dyke might be one of the feeders for the surrounding lava flows as these lavas are significantly younger than the majority of the main Deccan lavas of the Western Ghats (66.38–65.54 Ma. The second age of 56.95 ± 1.08 Ma comes from a younger dyke near Olini village which cuts across the lava flows of the area. The age correlates well with the Mandla lavas which are chemically similar to the uppermost Poladpur, Ambenali and Mahabaleshwar Formation lavas of SW Deccan. Our study shows that the dyke activities occurred in two phases, with the second one representing the terminal stage.

  3. Stepwise Differentiation of Pluripotent Stem Cells into Osteoblasts Using Four Small Molecules under Serum-free and Feeder-free Conditions

    Directory of Open Access Journals (Sweden)

    Kosuke Kanke

    2014-06-01

    Full Text Available Pluripotent stem cells are a promising tool for mechanistic studies of tissue development, drug screening, and cell-based therapies. Here, we report an effective and mass-producing strategy for the stepwise differentiation of mouse embryonic stem cells (mESCs and mouse and human induced pluripotent stem cells (miPSCs and hiPSCs, respectively into osteoblasts using four small molecules (CHIR99021 [CHIR], cyclopamine [Cyc], smoothened agonist [SAG], and a helioxanthin-derivative 4-(4-methoxyphenylpyrido[4′,3′:4,5]thieno[2,3-b]pyridine-2-carboxamide [TH] under serum-free and feeder-free conditions. The strategy, which consists of mesoderm induction, osteoblast induction, and osteoblast maturation phases, significantly induced expressions of osteoblast-related genes and proteins in mESCs, miPSCs, and hiPSCs. In addition, when mESCs defective in runt-related transcription factor 2 (Runx2, a master regulator of osteogenesis, were cultured by the strategy, they molecularly recapitulated osteoblast phenotypes of Runx2 null mice. The present strategy will be a platform for biological and pathological studies of osteoblast development, screening of bone-augmentation drugs, and skeletal regeneration.

  4. Efficient generation of transgene- and feeder-free induced pluripotent stem cells from human dental mesenchymal stem cells and their chemically defined differentiation into cardiomyocytes.

    Science.gov (United States)

    Tan, Xiaobing; Dai, Qingli; Guo, Tao; Xu, Jingshu; Dai, Qingyuan

    2018-01-22

    Advance in stem cell research resulted in several processes to generate induced pluripotent stem cells (iPSCs) from adult somatic cells. In our previous study, the reprogramming of iPSCs from human dental mesenchymal stem cells (MSCs) including SCAP and DPSCs, has been reported. Herein, safe iPSCs were reprogrammed from SCAP and DPSCs using non-integrating RNA virus vector, which is an RNA virus carrying no risk of altering host genome. DPSCs- and SCAP-derived iPSCs exhibited the characteristics of the classical morphology with human embryonic stem cells (hESCs) without integration of foreign genes, indicating the potential of their clinical application. Moreover, induced PSCs showed the capacity of self-renewal and differentiation into cardiac myocytes. We have achieved the differentiation of hiPSCs to cardiomyocytes lineage under serum and feeder-free conditions, using a chemically defined medium CDM3. In CDM3, hiPSCs differentiation is highly generating cardiomyocytes. The results showed this protocol produced contractile sheets of up to 97.2% TNNT2 cardiomyocytes after purification. Furthermore, derived hiPSCs differentiated to mature cells of the three embryonic germ layers in vivo and in vitro of beating cardiomyocytes. The above whole protocol enables the generation of large scale of highly pure cardiomyocytes as needed for cellular therapy. Copyright © 2017. Published by Elsevier Inc.

  5. Induced pluripotent stem cells generated from human adipose-derived stem cells using a non-viral polycistronic plasmid in feeder-free conditions.

    Directory of Open Access Journals (Sweden)

    Xinjian Qu

    Full Text Available Induced pluripotent stem cells (iPSCs can be generated from somatic cells by ectopic expression of defined transcription factors (TFs. However, the optimal cell type and the easy reprogramming approaches that minimize genetic aberrations of parent cells must be considered before generating the iPSCs. This paper reports a method to generate iPSCs from adult human adipose-derived stem cells (hADSCs without the use of a feeder layer, by ectopic expression of the defined transcription factors OCT4, SOX2, KLF4 and C-MYC using a polycistronic plasmid. The results, based on the expression of pluripotent marker, demonstrated that the iPSCs have the characteristics similar to those of embryonic stem cells (ESCs. The iPSCs differentiated into three embryonic germ layers both in vitro by embryoid body generation and in vivo by teratoma formation after being injected into immunodeficient mice. More importantly, the plasmid DNA does not integrate into the genome of human iPSCs as revealed by Southern blotting experiments. Karyotypic analysis also demonstrated that the reprogramming of hADSCs by the defined factors did not induce chromosomal abnormalities. Therefore, this technology provides a platform for studying the biology of iPSCs without viral vectors, and can hopefully overcome immune rejection and ethical concerns, which are the two important barriers of ESC applications.

  6. Simulating Global AeroMACS Airport Ground Station Antenna Power Transmission Limits to Avoid Interference With Mobile Satellite Service Feeder Uplinks

    Science.gov (United States)

    Wilson, Jeffrey D.

    2013-01-01

    The Aeronautical Mobile Airport Communications System (AeroMACS), which is based upon the IEEE 802.16e mobile wireless standard, is expected to be implemented in the 5091 to 5150 MHz frequency band. As this band is also occupied by Mobile Satellite Service feeder uplinks, AeroMACS must be designed to avoid interference with this incumbent service. The aspects of AeroMACS operation that present potential interference are under analysis in order to enable the definition of standards that assure that such interference will be avoided. In this study, the cumulative interference power distribution at low Earth orbit from transmitters at global airports was simulated with the Visualyse Professional software. The dependence of the interference power on antenna distribution, gain patterns, duty cycle, and antenna tilt was simulated. As a function of these parameters, the simulation results are presented in terms of the limitations on transmitter power from global airports required to maintain the cumulative interference power under the established threshold.

  7. The influence of interleukin-2, feeder cells, and timing of irradiation on the radiosensitivity of human T lymphocytes assessed by the colony-forming assay

    International Nuclear Information System (INIS)

    Gerber, M.; Guichard, M.; Pioch, Y.; Dubois, J.B.

    1989-01-01

    The radiosensitivity of human lymphocytes was investigated by the method of colony formation in the absence of interleukin-2 (IL2) and feeder cells, both of which enhance growth of T-cell colonies. The shape of the survival curve and the radiosensitivity was shown to depend upon the ability of lymphocytes to produce IL2: the survival curve for lymphocytes that were the most competent producers of IL2 is the closest to linearity; the lymphocytes that were poor producers show biphasic survival curves. The radiosensitivity of the lymphocytes from the first group is less than that of the latter, when the comparison is based on the first part of the biphasic survival curve. This is more easily seen when cultures are irradiated 24 h after stimulation by phytohemagglutinin (the time of the peak IL2 production) than when cultures are irradiated 2 h before stimulation. This study demonstrates that growth conditions influence the response of lymphocytes to irradiation and that optimal growth conditions result in a linear survival curve

  8. Constant DC-Capacitor Voltage-Control-Based Harmonics Compensation Strategy of Smart Charger for Electric Vehicles in Single-Phase Three-Wire Distribution Feeders

    Directory of Open Access Journals (Sweden)

    Fuka Ikeda

    2017-06-01

    Full Text Available This paper discusses harmonic current compensation of the constant DC-capacitor voltage-control (CDCVC-based strategy of smart chargers for electric vehicles (EVs in single-phase three-wire distribution feeders (SPTWDFs under nonlinear load conditions. The basic principle of the CDCVC-based harmonics compensation strategy under nonlinear load conditions is discussed in detail. The instantaneous power flowing into the three-leg pulse-width modulated (PWM rectifier, which performs as a smart charger, shows that the CDCVC-based strategy achieves balanced and sinusoidal source currents with a unity power factor. The CDCVC-based harmonics compensation strategy does not require any calculation blocks of fundamental reactive, unbalanced active, and harmonic currents. Thus, the authors propose a simplified algorithm to compensate for reactive, unbalanced active, and harmonic currents. A digital computer simulation is implemented to confirm the validity and high practicability of the CDCVC-based harmonics compensation strategy using PSIM software. Simulation results demonstrate that balanced and sinusoidal source currents with a unity power factor in SPTWDFs are obtained on the secondary side of the pole-mounted distribution transformer (PMDT during both the battery-charging and discharging operations in EVs, compensating for the reactive, unbalanced active, and harmonic currents.

  9. Design to Cost and Life Cycle Cost.

    Science.gov (United States)

    1980-07-01

    MANAGEMENT TASK ORIENTATED COST STRUCTURE 5. COSTS OF CONSTRUCTION INIFRA 2. COSTS DURING DEVELOPMENT -6. COSTS OF TRAINING 3. COSTS DURING TESi ...de r~duction des coats, ii faut disponer de ?!vyenr. performants d’eetimation des coats en main-d’oeuvre et en applrvininrinesent. Cam moyenm doivent

  10. A Cost to Benefit Analysis of a Next Generation Electric Power Distribution System

    Science.gov (United States)

    Raman, Apurva

    This thesis provides a cost to benefit analysis of the proposed next generation of distribution systems- the Future Renewable Electric Energy Distribution Management (FREEDM) system. With the increasing penetration of renewable energy sources onto the grid, it becomes necessary to have an infrastructure that allows for easy integration of these resources coupled with features like enhanced reliability of the system and fast protection from faults. The Solid State Transformer (SST) and the Fault Isolation Device (FID) make for the core of the FREEDM system and have huge investment costs. Some key features of the FREEDM system include improved power flow control, compact design and unity power factor operation. Customers may observe a reduction in the electricity bill by a certain fraction for using renewable sources of generation. There is also a possibility of huge subsidies given to encourage use of renewable energy. This thesis is an attempt to quantify the benefits offered by the FREEDM system in monetary terms and to calculate the time in years required to gain a return on investments made. The elevated cost of FIDs needs to be justified by the advantages they offer. The result of different rates of interest and how they influence the payback period is also studied. The payback periods calculated are observed for viability. A comparison is made between the active power losses on a certain distribution feeder that makes use of distribution level magnetic transformers versus one that makes use of SSTs. The reduction in the annual active power losses in the case of the feeder using SSTs is translated onto annual savings in terms of cost when compared to the conventional case with magnetic transformers. Since the FREEDM system encourages operation at unity power factor, the need for installing capacitor banks for improving the power factor is eliminated and this reflects in savings in terms of cost. The FREEDM system offers enhanced reliability when compared to a

  11. Generation of functional cardiomyocytes from rat embryonic and induced pluripotent stem cells using feeder-free expansion and differentiation in suspension culture.

    Science.gov (United States)

    Dahlmann, Julia; Awad, George; Dolny, Carsten; Weinert, Sönke; Richter, Karin; Fischer, Klaus-Dieter; Munsch, Thomas; Leßmann, Volkmar; Volleth, Marianne; Zenker, Martin; Chen, Yaoyao; Merkl, Claudia; Schnieke, Angelika; Baraki, Hassina; Kutschka, Ingo; Kensah, George

    2018-01-01

    The possibility to generate cardiomyocytes from pluripotent stem cells in vitro has enormous significance for basic research, disease modeling, drug development and heart repair. The concept of heart muscle reconstruction has been studied and optimized in the rat model using rat primary cardiovascular cells or xenogeneic pluripotent stem cell derived-cardiomyocytes for years. However, the lack of rat pluripotent stem cells (rPSCs) and their cardiovascular derivatives prevented the establishment of an authentic clinically relevant syngeneic or allogeneic rat heart regeneration model. In this study, we comparatively explored the potential of recently available rat embryonic stem cells (rESCs) and induced pluripotent stem cells (riPSCs) as a source for cardiomyocytes (CMs). We developed feeder cell-free culture conditions facilitating the expansion of undifferentiated rPSCs and initiated cardiac differentiation by embryoid body (EB)-formation in agarose microwell arrays, which substituted the robust but labor-intensive hanging drop (HD) method. Ascorbic acid was identified as an efficient enhancer of cardiac differentiation in both rPSC types by significantly increasing the number of beating EBs (3.6 ± 1.6-fold for rESCs and 17.6 ± 3.2-fold for riPSCs). These optimizations resulted in a differentiation efficiency of up to 20% cTnTpos rPSC-derived CMs. CMs showed spontaneous contractions, expressed cardiac markers and had typical morphological features. Electrophysiology of riPSC-CMs revealed different cardiac subtypes and physiological responses to cardio-active drugs. In conclusion, we describe rPSCs as a robust source of CMs, which is a prerequisite for detailed preclinical studies of myocardial reconstruction in a physiologically and immunologically relevant small animal model.

  12. Spatio-Temporal Variation in Effects of Upwelling on the Fatty Acid Composition of Benthic Filter Feeders in the Southern Benguela Ecosystem: Not All Upwelling Is Equal.

    Directory of Open Access Journals (Sweden)

    Eleonora Puccinelli

    Full Text Available Variability in mesoscale nearshore oceanographic conditions plays an important role in the distribution of primary production and food availability for intertidal consumers. Advection of nutrient rich waters by upwelling usually allows the proliferation of diatoms, later replaced by dinoflagellates. We examined upwelling effects on the fatty acid (FA signature of a benthic intertidal filter feeder to identify its response to pulsed variability in food availability. The study took place in two contrasting seasons and at two upwelling and two non-upwelling sites interspersed within the southern Benguela upwelling system of South Africa. We investigated the FA composition of the adductor muscles and gonads of the mussel Mytilus galloprovincialis to assess how FA are apportioned to the different tissues and whether this changes between upwelling and non-upwelling conditions. In situ temperature loggers used to identify upwelling conditions at the four sites indicated that such events occurred only at the upwelling centres and only in summer. Tissues differed strongly, with gonads presenting a higher proportion of essential FAs. This could reflect the faster turnover rate of gonad tissue or preferential retention of specific FA for reproductive purposes. FA composition did not vary as a direct function of upwelling, but there were strong dissimilarities among sites. Upwelling influenced mussel diets at one upwelling site while at the other, the expected signature of upwelling was displaced downstream of the core of upwelling. Condition Index (CI and Gonad Index (GI differed among sites and were not influenced by upwelling, with GI being comparable among sites. In addition, FA proportions were consistent among sites, indicating similar food quality and quantity over time and under upwelling and non-upwelling conditions. This suggests that the influence of upwelling on the west coast of South Africa is pervasive and diffuse, rather than discrete; while

  13. Geometric design of part feeders

    NARCIS (Netherlands)

    Berretty, R.-P.M.

    2000-01-01

    This thesis presents solutions for problems derived from industrial assembly and robotic manipulation. The basic tasks in a factory are manufacturing the parts, and combining them into the desired product. In automating these tasks, we want to use robot manipulators that require little or no

  14. Road crash costs.

    NARCIS (Netherlands)

    2010-01-01

    Road crashes result in all kinds of social costs, such as medical costs, production loss, human losses, property damage, settlement costs and costs due to congestion. Studies into road crash costs and their trends are carried out quite regularly. In 2009, the costs amounted to € 12.5 billion, or

  15. Quasi-static time-series simulation using OpenDSS in IEEE distribution feeder model with high PV penetration and its impact on solar forecasting

    Science.gov (United States)

    Mohammed, Touseef Ahmed Faisal

    Distribution System Simulator developed by Electric Power Research Institute, to simulate grid voltage profile with a large scale PV system under quasi-static time series considering variations of PV output in seconds, minutes, and the average daily load variations. A 13 bus IEEE distribution feeder model is utilized with distributed residential and commercial scale PV at different buses for simulation studies. Time series simulations are discussed for various modes of operation considering dynamic PV penetration at different time periods in a day. In addition, this thesis demonstrates simulations taking into account the presence of moving cloud for solar forecasting studies.

  16. COST MEASUREMENT AND COST MANAGEMENT IN TARGET COSTING

    Directory of Open Access Journals (Sweden)

    Moisello Anna Maria

    2012-07-01

    Full Text Available Firms are coping with a competitive scenario characterized by quick changes produced by internationalization, concentration, restructuring, technological innovation processes and financial market crisis. On the one hand market enlargement have increased the number and the segmentation of customers and have raised the number of competitors, on the other hand technological innovation has reduced product life cycle. So firms have to adjust their management models to this scenario, pursuing customer satisfaction and respecting cost constraints. In a context where price is a variable fixed by the market, firms have to switch from the cost measurement logic to the cost management one, adopting target costing methodology. The target costing process is a price driven, customer oriented profit planning and cost management system. It works, in a cross functional way, from the design stage throughout all the product life cycle and it involves the entire value chain. The process implementation needs a costing methodology consistent with the cost management logic. The aim of the paper is to focus on Activity Based Costing (ABC application to target costing process. So: -it analyzes target costing logic and phases, basing on a literary review, in order to highlight the costing needs related to this process; -it shows, through a numerical example, how to structure a flexible ABC model – characterized by the separation between variable, fixed in the short and fixed costs - that effectively supports target costing process in the cost measurement phase (drifting cost determination and in the target cost alignment; -it points out the effectiveness of the Activity Based Costing as a model of cost measurement applicable to the supplier choice and as a support for supply cost management which have an important role in target costing process. The activity based information allows a firm to optimize the supplier choice by following the method of minimizing the

  17. How to insure measurement accuracy of belt feeder machine weighing installment%如何保证皮带绐料机称重装置的计量精度

    Institute of Scientific and Technical Information of China (English)

    李双; 吴江; 陈以振

    2012-01-01

    本文从皮带给料机这一称重产品的结构、校准原理、计量精度等几个主要方面,以图文结合的形式着重阐述了怎样保证皮带给料机称重装置的计量精度。%In the form of a graphic combination, according to structure, calibration principle, measurement accuracy and some other factors, this article elaborates how to insure measurement accuracy of belt feeder machine weighing installmenL

  18. COSTS CALCULATION OF TARGET COSTING METHOD

    Directory of Open Access Journals (Sweden)

    Sebastian UNGUREANU

    2014-06-01

    Full Text Available Cost information system plays an important role in every organization in the decision making process. An important task of management is ensuring control of the operations, processes, sectors, and not ultimately on costs. Although in achieving the objectives of an organization compete more control systems (production control, quality control, etc., the cost information system is important because monitors results of the other. Detailed analysis of costs, production cost calculation, quantification of losses, estimate the work efficiency provides a solid basis for financial control. Knowledge of the costs is a decisive factor in taking decisions and planning future activities. Managers are concerned about the costs that will appear in the future, their level underpinning the supply and production decisions as well as price policy. An important factor is the efficiency of cost information system in such a way that the information provided by it may be useful for decisions and planning of the work.

  19. Life cycle cost analysis rehabilitation costs.

    Science.gov (United States)

    2015-07-01

    This study evaluates data from CDOTs Cost Data books and Pavement Management Program. Cost : indices were used to normalize project data to year 2014. Data analyzed in the study was obtained from : the CDOTs Cost Data books and the Pavement Man...

  20. Process-based costing.

    Science.gov (United States)

    Lee, Robert H; Bott, Marjorie J; Forbes, Sarah; Redford, Linda; Swagerty, Daniel L; Taunton, Roma Lee

    2003-01-01

    Understanding how quality improvement affects costs is important. Unfortunately, low-cost, reliable ways of measuring direct costs are scarce. This article builds on the principles of process improvement to develop a costing strategy that meets both criteria. Process-based costing has 4 steps: developing a flowchart, estimating resource use, valuing resources, and calculating direct costs. To illustrate the technique, this article uses it to cost the care planning process in 3 long-term care facilities. We conclude that process-based costing is easy to implement; generates reliable, valid data; and allows nursing managers to assess the costs of new or modified processes.

  1. The SYOEKSY research project. Electrically-powered vehicles in ring rail line feeder traffic and short-distance travel; Saehkoeiset ajoneuvot kehaeradan syoettoe- ja asiointiliikenteessae. SYOEKSY-tutkimushankkeen loppuraportti 21.9.2011

    Energy Technology Data Exchange (ETDEWEB)

    2011-07-01

    The research report is divided into three sections: a general description of the project, separate reports on each of the themes investigated and a summary of the research results and recommendations. Section 2 deals with themes such as: Low-emissions-technology solutions for traffic and their technical prerequisites in an urban environment and the results obtained from pilot projects. New service models based on electrically-powered traffic technology with an assessment of their feasibility and their effect on urban infrastructure and levels of CO{sub 2} emissions. User needs in new feeder traffic, short-distance travel and other journeys on personal business together with proposals for planning measures which will promote sustainable mobility in new residential areas. The prerequisites for electrically-powered feeder traffic and short-distance travel are therefore handled in a wide-ranging manner. A condensed version of the project conclusions and recommendations is provided in Section 3. A list of the data sources and publications resulting from project work can be found at the end of the report

  2. Photovoltaic energy cost limit

    International Nuclear Information System (INIS)

    Coiante, D.

    1992-01-01

    Referring to a photovoltaic system for grid connected applications, a parametric expression of kWh cost is derived. The limit of kWh cost is carried out extrapolating the values of cost components to their lowest figure. The reliability of the forecast is checked by disaggregating kWh cost in direct and indirect costs and by discussing the possible cost reduction of each component

  3. Suction power output and the inertial cost of rotating the neurocranium to generate suction in fish.

    Science.gov (United States)

    Van Wassenbergh, Sam; Day, Steven W; Hernández, L Patricia; Higham, Timothy E; Skorczewski, Tyler

    2015-05-07

    To expand the buccal cavity, many suction-feeding fishes rely on a considerable contribution from dorsal rotation of the dorsal part of the head including the brains, eyes, and several bones forming the braincase and skull roof (jointly referred to as the neurocranium). As the neurocranium takes up a large part of the total mass of the head, this rotation may incur a considerable inertial cost. If so, this would suggest a significant selective pressure on the kinematics and mass distribution of the neurocranium of suction feeders. Here, an inverse dynamic model is formulated to calculate the instantaneous power required to rotate the neurocranium, approximated by a quarter ellipsoid volume of homogeneous density, as well as to calculate the instantaneous suction power based on intra-oral pressure and head volume quantifications. We applied this model to largemouth bass (Micropterus salmoides) and found that the power required to rotate the neurocranium accounts for only about 4% of the power required to suck water into the mouth. Furthermore, recovery of kinetic energy from the rotating neurocranium converted into suction work may be possible during the phase of neurocranial deceleration. Thus, we suggest that only a negligible proportion of the power output of the feeding muscles is lost as inertial costs in the largemouth bass. Consequently, the feeding performance of piscivorous suction feeders with generalised morphology, comparable to our model species, is not limited by neurocranial motion during head expansion. This suggests that it is thus not likely to be a factor of importance in the evolution of cranial shape and size. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Implementing Replacement Cost Accounting

    Science.gov (United States)

    1976-12-01

    cost accounting Clickener, John Ross Monterey, California. Naval Postgraduate School http://hdl.handle.net/10945/17810 Downloaded from NPS Archive...Calhoun IMPLEMENTING REPLACEMENT COST ACCOUNTING John Ross CHckener NAVAL POSTGRADUATE SCHOOL Monterey, California THESIS IMPLEMENTING REPLACEMENT COST ...Implementing Replacement Cost Accounting 7. AUTHORS John Ross Clickener READ INSTRUCTIONS BEFORE COMPLETING FORM 3. RECIPIENT’S CATALOG NUMBER 9. TYRE OF

  5. Características de las fallas en alimentadores de 13,8 kV del sistema soterrado de La Habana;Characteristic of 13,8 kV feeders faults of the Havana underground system

    Directory of Open Access Journals (Sweden)

    Boris Alba - Valle

    2011-06-01

    Full Text Available El sistema soterrado de La Habana enfrenta problemas de continuas fallas en sus alimentadores de 13,8 kV. En este trabajo se determinan las características de estas averías, en el período comprendido entre los años 2007 y 2009, y se proponen algunas medidas objetivas con el fin de contribuir a su disminución. La investigación se basó fundamentalmente en el estudio de la base de datos de los alimentadores de 13,8 kV proporcionada por el departamento técnico de la Unidad Empresarial Básica (UEB Soterrada y en el uso de herramientas estadísticas digitales. Como resultado se pudo constatar que las fallas son más frecuentes en los alimentadores de la subestación de Tallapiedra producto de la humedad en cables y empalmes con aislamiento de PILC (papel impregnado en aceite y con cubierta de plomo, dispuestos por tierra muerta. Finalmente, las medidas propuestas tuvieron un impacto positivo en la disminución de estas fallas, en un período inferior a un año.The Havana underground system has problems of continuous faults in their 13,8 kV feeders. In this article the characteristics of these mishaps in the period of 2007 to 2009 are determined and purpose some objective measurements with the end of contributing to their decrease. The investigation was fundamentally based on the study of the 13,8 kV feeders database proportioned by the technical department of the Underground Basic Managerial Unit (UEB and the use of digital statistical tools. As a result, it was verified that the faults occur with more frequency in the Tallapiedra substation feeders, due to the humidity in cables and connections with PILC isolation (impregnated in oil and lead covered paper, prepared for undergrounding directly in the earth. Finally, the proposed measures had a positive impact in the decrease of these faults, in a period less than to a year.

  6. Controlling Healthcare Costs: Just Cost Effectiveness or "Just" Cost Effectiveness?

    Science.gov (United States)

    Fleck, Leonard M

    2018-04-01

    Meeting healthcare needs is a matter of social justice. Healthcare needs are virtually limitless; however, resources, such as money, for meeting those needs, are limited. How then should we (just and caring citizens and policymakers in such a society) decide which needs must be met as a matter of justice with those limited resources? One reasonable response would be that we should use cost effectiveness as our primary criterion for making those choices. This article argues instead that cost-effectiveness considerations must be constrained by considerations of healthcare justice. The goal of this article will be to provide a preliminary account of how we might distinguish just from unjust or insufficiently just applications of cost-effectiveness analysis to some healthcare rationing problems; specifically, problems related to extraordinarily expensive targeted cancer therapies. Unconstrained compassionate appeals for resources for the medically least well-off cancer patients will be neither just nor cost effective.

  7. OOTW COST TOOLS

    Energy Technology Data Exchange (ETDEWEB)

    HARTLEY, D.S.III; PACKARD, S.L.

    1998-09-01

    This document reports the results of a study of cost tools to support the analysis of Operations Other Than War (OOTW). It recommends the continued development of the Department of Defense (DoD) Contingency Operational Support Tool (COST) as the basic cost analysis tool for 00TWS. It also recommends modifications to be included in future versions of COST and the development of an 00TW mission planning tool to supply valid input for costing.

  8. Nuclear fuel cycle cost and cost calculation

    International Nuclear Information System (INIS)

    Schmiedel, P.; Schricker, W.

    1975-01-01

    Four different methods of calculating the cost of the fuel cycle are explained, starting from the individual cost components with their specific input data. The results (for LWRs) are presented in tabular form and in the form of diagrams. (RB) [de

  9. Minimum cost connection networks

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Tvede, Mich

    2015-01-01

    In the present paper we consider the allocation of costs in connection networks. Agents have connection demands in form of pairs of locations they want to have connected. Connections between locations are costly to build. The problem is to allocate costs of networks satisfying all connection...... demands. We use a few axioms to characterize allocation rules that truthfully implement cost minimizing networks satisfying all connection demands in a game where: (1) a central planner announces an allocation rule and a cost estimation rule; (2) every agent reports her own connection demand as well...... as all connection costs; (3) the central planner selects a cost minimizing network satisfying reported connection demands based on the estimated costs; and, (4) the planner allocates the true costs of the selected network. It turns out that an allocation rule satisfies the axioms if and only if relative...

  10. Costing Practices in Healthcare

    DEFF Research Database (Denmark)

    Chapman, Christopher; Kern, Anja; Laguecir, Aziza

    2014-01-01

    .e., Diagnosis Related Group (DRG) systems, and costing practices. DRG-based payment systems strongly influence costing practices in multiple ways. In particular, setting DRG tariffs requires highly standardized costing practices linked with specific skill sets from management accountants and brings other...... jurisdictions (e.g., clinical coding) to bear on costing practice. These factors contribute to the fragmentation of the jurisdiction of management accounting.......The rising cost of healthcare is a globally pressing concern. This makes detailed attention to the way in which costing is carried out of central importance. This article offers a framework for considering the interdependencies between a dominant element of the contemporary healthcare context, i...

  11. Cultivation and irradiation of human fibroblasts in a medium enriched with platelet lysate for obtaining feeder layer in epidermal cell culture; Cultivo e irradiacao de fibroblastos humanos em meio enriquecido com lisado de plaquetas para obtencao de camada de sustentacao em culturas de celulas da epiderme

    Energy Technology Data Exchange (ETDEWEB)

    Yoshito, Daniele

    2011-07-01

    For over 30 years, the use of culture medium, enriched with bovine serum, and murines fibroblasts, with the rate of proliferation controlled by irradiation or by share anticarcinogenic drugs, has been playing successfully its role in assisting in the development of keratinocytes in culture, for clinical purposes. However, currently there is a growing concern about the possibility of transmitting prions and animals viruses to transplanted patients. Taking into account this concern, the present work aims to cultivate human fibroblasts in a medium enriched with human platelets lysate and determine the irradiation dose of these cells, for obtaining feeder layer in epidermal cell culture. For carrying out the proposed objective, platelets lysis has standardized, this lysate was used for human fibroblasts cultivation and the irradiation dose enough to inhibit its duplication was evaluated. Human keratinocytes were cultivated in these feeder layers, in culture medium enriched with the lysate. With these results we conclude that the 10% platelets lysate promoted a better adhesion and proliferation of human fibroblasts and in all dose levels tested (60 to 300 Gy), these had their mitotic activity inactivated by ionizing irradiation, being that the feeder layers obtained with doses from 70 to 150 Gy were those that provided the best development of keratinocytes in medium containing 2.5% of human platelet lysate. Therefore, it was possible to standardize both the cultivation of human fibroblasts as its inactivation for use as feeder layer in culture of keratinocytes, so as to eliminate xenobiotics components. (author)

  12. Cost benefit analysis cost effectiveness analysis

    International Nuclear Information System (INIS)

    Lombard, J.

    1986-09-01

    The comparison of various protection options in order to determine which is the best compromise between cost of protection and residual risk is the purpose of the ALARA procedure. The use of decision-aiding techniques is valuable as an aid to selection procedures. The purpose of this study is to introduce two rather simple and well known decision aiding techniques: the cost-effectiveness analysis and the cost-benefit analysis. These two techniques are relevant for the great part of ALARA decisions which need the use of a quantitative technique. The study is based on an hypothetical case of 10 protection options. Four methods are applied to the data

  13. Unit Cost Compendium Calculations

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Unit Cost Compendium (UCC) Calculations raw data set was designed to provide for greater accuracy and consistency in the use of unit costs across the USEPA...

  14. Realized Cost Savings 2016

    Data.gov (United States)

    Department of Veterans Affairs — This dataset is provided as a requirement of OMB’s Integrated Data Collection (IDC) and links to VA’s Realized Cost Savings and Avoidances data in JSON format. Cost...

  15. Cost accounting at GKSS

    International Nuclear Information System (INIS)

    Hinz, R.

    1979-01-01

    The GKSS has a cost accounting system comprising cost type, cost centre and cost unit accounting which permits of a comprehensive and detailed supervision of the accural of costs and use of funds, makes price setting for outside orders possible and provides the necessary data for decision-making and planning. It fulfills the requirement for an ordered accounting system; it is therefore guaranteed that there exists between financial accounts department and cost accounting a proper demarcation and transition, that costs are accounted fully only on the basis of vouchers and only once, evaluation and distribution are unified and the principle of causation is observed. Two employees are engaged in costs and services accounting. Although we strive to effect adaptations as swiftly as possible, and constantly to adapt refinements and supplementary processes for the improvement of the system, this can only occur within the scope of, and with the exactitude necessary for the required information. (author)

  16. INTOR cost approximation

    International Nuclear Information System (INIS)

    Knobloch, A.F.

    1980-01-01

    A simplified cost approximation for INTOR parameter sets in a narrow parameter range is shown. Plausible constraints permit the evaluation of the consequences of parameter variations on overall cost. (orig.) [de

  17. Medicare Cost Reports

    Data.gov (United States)

    U.S. Department of Health & Human Services — Medicare certified institutional providers are required to submit an annual cost report to a Medicare Administrative Contractor. The cost report contains provider...

  18. Cost accounting in ECN

    International Nuclear Information System (INIS)

    Wout, E.L.; Bever Donker, J.M. van.

    1979-01-01

    A five year planning is made in which the available money is distributed to the expected programmes. This five year plan is used as basis for working plan and budget for the next year. In the working plan all financial means are divided into kinds of costs, cost centres and cost units. Based on this working plan and the relevant budgets the tariffs are calculated per working centre (cost centre). The tariffs are fixed for a whole year. Up till now these tariffs are also basis for the cost unit accounting at the end of the year together with the results of the time registration. The estimated work shop services for the working centres are included in the tariffs. For the allocation of overhead costs ECN uses dynamic keys. Depreciation costs with respect to instruments, investments etc. are determined per working centre according to a computer programme. The cost unit related costs are charged directly to cost unit. This implies that project related in instruments are looked upon as running costs. In the future we will try to refine the present cost accounting system still further in this way that we will look upon a cost centre as a profit centre. Furthermore we will try to analyse the tariff and calculation deviations and under/over occupation deviations afterwards (post calculation). The information provided to the management knows a hierachic construction: project information to projectleader, programme (compound projects) information to programme coordinator, cost centre summary to department heads, attention area (compound programme) information to programme coordinator and managing director, ECN research (compound attention areas) information to general management, information re kind of costs to relevant persons, f.e. surveys of expenditure for part time personnel to personnel bureau. The information is provided by the department of Finance and Administrative Organisation. The entire scope of cost accounting is the responsibility of the head of the department

  19. Cost function estimation

    DEFF Research Database (Denmark)

    Andersen, C K; Andersen, K; Kragh-Sørensen, P

    2000-01-01

    on these criteria, a two-part model was chosen. In this model, the probability of incurring any costs was estimated using a logistic regression, while the level of the costs was estimated in the second part of the model. The choice of model had a substantial impact on the predicted health care costs, e...

  20. Costs of employee turnover

    Directory of Open Access Journals (Sweden)

    Jiří Duda

    2013-01-01

    Full Text Available The aim of this paper is to establish a general methodology for calculating the costs incurred by employee turnover. This paper deals with identification of costs incurred by the departure of an employee, and does not deal with the cost of recruitment of a new employee. Economic calculations are adjusted to the tax policy in the Czech Republic. The costs of employee turnover (according to Bliss, 2012 include the costs of substitution of the unoccupied position, costs of conducting the exit interview and termination of the contract. The cost of an executive’s time to understand the causes of leaving and costs of the leaving employee’s training were also determined. Important factors in the costs of employee turnover also include the loss of knowledge and possibly also a loss of customers. Costs of lost employee and department productiveness represent an important part of the costs of employee turnover, as well. For all of these costs there have been proposed general calculations formulas.

  1. Reactor cost driving items

    International Nuclear Information System (INIS)

    Spears, W.R.

    1987-01-01

    Assuming that the design solutions presently perceived for NET can be extrapolated for use in a power reactor, and using costing experience with present day fusion experiments and with fission power plants, the major components of the cost of a tokamak fusion power reactor are described. The analysis shows the emphasis worth placing on various areas of plant design to reduce costs

  2. Minimum cost connection networks

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Tvede, Mich

    In the present paper we consider the allocation of cost in connection networks. Agents have connection demands in form of pairs of locations they want to be connected. Connections between locations are costly to build. The problem is to allocate costs of networks satisfying all connection demands...

  3. Distribution costs -- the cost of local delivery

    International Nuclear Information System (INIS)

    Winger, N.; Zarnett, P.; Carr, J.

    2000-01-01

    Most of the power transmission system in the province of Ontario is owned and operated as a regulated monopoly by Ontario Hydro Services Company (OHSC). Local distribution systems deliver to end-users from bulk supply points within a service territory. OHSC distributes to approximately one million, mostly rural customers, while the approximately 250 municipal utilities together serve about two million, mostly urban customers. Under the Energy Competition Act of 1998 local distribution companies will face some new challenges, including unbundled billing systems, a broader range of distribution costs, increased costs, made up of corporate taxes or payments in lieu of taxes and added costs for regulatory affairs. The consultants provide a detailed discussion of the components of distribution costs, the three components of the typical budget process (capital expenditures, (CAPEX), operating and maintenance (O and M) and administration and corporate (GA and C), a summary of some typical distribution costs in Ontario, and the estimated impacts of the Energy Competition Act (ECA) compliance on charges and rates. Various mitigation strategies are also reviewed. Among these are joint ventures by local distribution companies to reduce ECA compliance costs, re-examination of controllable costs, temporary reduction of the allowable return on equity (ROE) by 50 per cent, and/or reducing the competitive transition charge (CTC). It is estimated that either one of these two reductions could eliminate the full amount of the five to seven per cent uplift in delivered energy service costs. The conclusion of the consultants is that local distribution delivery charges will make up a greater proportion of end-user cost in the future than it has in the past. An increase to customers of about five per cent is expected when the competitive electricity market opens and unbundled billing begins. The cost increase could be mitigated by a combination of actions that would be needed for about

  4. Cardiac rehabilitation costs.

    Science.gov (United States)

    Moghei, Mahshid; Turk-Adawi, Karam; Isaranuwatchai, Wanrudee; Sarrafzadegan, Nizal; Oh, Paul; Chessex, Caroline; Grace, Sherry L

    2017-10-01

    Despite the clinical benefits of cardiac rehabilitation (CR) and its cost-effectiveness, it is not widely received. Arguably, capacity could be greatly increased if lower-cost models were implemented. The aims of this review were to describe: the costs associated with CR delivery, approaches to reduce these costs, and associated implications. Upon finalizing the PICO statement, information scientists were enlisted to develop the search strategy of MEDLINE, Embase, CDSR, Google Scholar and Scopus. Citations identified were considered for inclusion by the first author. Extracted cost data were summarized in tabular format and qualitatively synthesized. There is wide variability in the cost of CR delivery around the world, and patients pay out-of-pocket for some or all of services in 55% of countries. Supervised CR costs in high-income countries ranged from PPP$294 (Purchasing Power Parity; 2016 United States Dollars) in the United Kingdom to PPP$12,409 in Italy, and in middle-income countries ranged from PPP$146 in Venezuela to PPP$1095 in Brazil. Costs relate to facilities, personnel, and session dose. Delivering CR using information and communication technology (mean cost PPP$753/patient/program), lowering the dose and using lower-cost personnel and equipment are important strategies to consider in containing costs, however few explicitly low-cost models are available in the literature. More research is needed regarding the costs to deliver CR in community settings, the cost-effectiveness of CR in most countries, and the economic impact of return-to-work with CR participation. A low-cost model of CR should be standardized and tested for efficacy across multiple healthcare systems. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Costs of traffic injuries

    DEFF Research Database (Denmark)

    Kruse, Marie

    2015-01-01

    assessed using Danish national healthcare registers. Productivity costs were computed using duration analysis (Cox regression models). In a subanalysis, cost per severe traffic injury was computed for the 12 995 individuals that experienced a severe injury. RESULTS: The socioeconomic cost of a traffic...... injury was €1406 (2009 price level) in the first year, and €8950 over a 10-year period. Per 100 000 population, the 10-year cost was €6 565 668. A severe traffic injury costs €4969 per person in the first year, and €4 006 685 per 100 000 population over a 10-year period. Victims of traffic injuries...

  6. Cost of stroke

    DEFF Research Database (Denmark)

    Jennum, Poul; Iversen, Helle K; Ibsen, Rikke

    2015-01-01

    . The attributable cost of direct net health care costs after the stroke (general practitioner services, hospital services, and medication) and indirect costs (loss of labor market income) were €10,720, €8,205 and €7,377 for patients, and €989, €1,544 and €1.645 for their partners, over and above that of controls......BACKGROUND: To estimate the direct and indirect costs of stroke in patients and their partners. DESCRIPTION: Direct and indirect costs were calculated using records from the Danish National Patient Registry from 93,047 ischemic, 26,012 hemorrhagic and 128,824 unspecified stroke patients...

  7. Cost incentives for doctors

    DEFF Research Database (Denmark)

    Schottmüller, Christoph

    2013-01-01

    If doctors take the costs of treatment into account when prescribing medication, their objectives differ from their patients' objectives because the patients are insured. This misalignment of interests hampers communication between patient and doctor. Giving cost incentives to doctors increases...... welfare if (i) the doctor's examination technology is sufficiently good or (ii) (marginal) costs of treatment are high enough. If the planner can costlessly choose the extent to which doctors take costs into account, he will opt for less than 100%. Optimal health care systems should implement different...... degrees of cost incentives depending on type of disease and/or doctor....

  8. The disarmament cost

    International Nuclear Information System (INIS)

    Cattaneo, M.

    1996-01-01

    War is costly. But peace cost is even higher. The destruction of weapons (mines, nuclear weapons, chemical weapons) is much more expensive than their manufacturing. The soldiers demobilization cost is enormous, for instance in Angola, Mozambique, Nicaragua, Zimbabwe the demobilization of 270000 soldiers cost 2.5 10 9 francs. The measures intended to reduce the war risk are also expensive. That is why the arsenal of ex USSR is still intact. Today no international agency is entirely dedicated to peace building. The question is how would cost such an agency? (O.L.). 5 refs., 2 figs

  9. Costs of groundwater contamination

    International Nuclear Information System (INIS)

    O'Neil, W.B.; Raucher, R.S.

    1990-01-01

    Two factors determine the cost of groundwater contamination: (1) the ways in which water was being used or was expected to be used in the future and (2) the physical characteristics of the setting that constrain the responses available to regain lost uses or to prevent related damages to human health and the environment. Most contamination incidents can be managed at a low enough cost that uses will not be foreclosed. It is important to take into account the following when considering costs: (1) natural cleansing through recharge and dilution can take many years; (2) it is difficult and costly to identify the exact area and expected path of a contamination plume; and (3) treatment or replacement of contaminated water often may represent the cost-effective strategy for managing the event. The costs of contamination include adverse health effects, containment and remediation, treatment and replacement costs. In comparing the costs and benefits of prevention programs with those of remediation, replacement or treatment, it is essential to adjust the cost/benefit numbers by the probability of their actual occurrence. Better forecasts of water demand are needed to predict more accurately the scarcity of new supply and the associated cost of replacement. This research should include estimates of the price elasticity of water demand and the possible effect on demand of more rational cost-based pricing structures. Research and development of techniques for in situ remediation should be encouraged

  10. Costs associated with wheeling

    International Nuclear Information System (INIS)

    Anon.

    1991-01-01

    Wheeling costs are incurred by all companies that experience a change in power flows over their transmission lines during a specific transaction, whether or not the lines of that company are part of the contract path. The costs of providing wheeling service differ from one system to another and from one kind of wheeling transaction to another. While most transactions may be completed using existing capacity, others may require an increase in line. Depending on the situation, some cost components may be high, low, negative, or not incurred at all. This article discusses two general categories of costs; transactional and capital. The former are all operation, maintenance and opportunity costs incurred in completing a specific transaction assuming the existence of adequate capacity. Capital costs are the costs of major new equipment purchases and lines necessary to provide any increased level of transmission services

  11. 77 FR 43542 - Cost Accounting Standards: Cost Accounting Standards 412 and 413-Cost Accounting Standards...

    Science.gov (United States)

    2012-07-25

    ... rule that revised Cost Accounting Standard (CAS) 412, ``Composition and Measurement of Pension Cost... Accounting Standards: Cost Accounting Standards 412 and 413--Cost Accounting Standards Pension Harmonization Rule AGENCY: Cost Accounting Standards Board, Office of Federal Procurement Policy, Office of...

  12. The cost of electrocoagulation

    Energy Technology Data Exchange (ETDEWEB)

    Donini, J.C.; Kan, J.; Szynkarczuk, J.; Hassan, T.A.; Kar, K.L.

    1993-01-01

    Electrocoagulation could be an attractive and suitable method for separating solids from waste water. The electrocoagulation of kaolinite and bentonite suspensions was studied in a pilot electrocoagulation unit to assess the cost and efficiency of the process. Factors affecting cost such as the formation of passivation layers on electrode plates and the recirculation and concentration of sodium chloride were examined. Colorimetry was used to analyze aluminum content in the suspension. The results were used to calculate the cost due to consumption of electrode material (aluminium) during the process. Total cost was assumed to comprise the energy cost and the cost of electrode material. Comparison was based on the settling properties of the treated product: turbidity, settling rate, and cake height. In most cases, aluminium efficiency averaged around 200% and material cost accounted for 80% of total cost. Although higher concentrations of sodium chloride could only slightly increase aluminium efficiency and electrode efficiency, the higher concentrations resulted in much greater total cost, due to the greater current generated by the increased suspension conductivity, which in turn dissolved a larger amount of aluminium. The recirculation loop increased the flow rate by 3-10 times, enhancing the mass transport between the electrodes and resulting in lower cost and better settling properties. Over the course of two months the electrodes coatings became thicker while efficiency decreased. The electrode efficiency was found to be as high as 94% for virgin electrodes and as low as 10% after two months. 8 refs., 25 figs., 9 tabs.

  13. Equipment cost optimization

    International Nuclear Information System (INIS)

    Ribeiro, E.M.; Farias, M.A.; Dreyer, S.R.B.

    1995-01-01

    Considering the importance of the cost of material and equipment in the overall cost profile of an oil company, which in the case of Petrobras, represents approximately 23% of the total operational cost or 10% of the sales, an organization for the optimization of such costs has been established within Petrobras. Programs are developed aiming at: optimization of life-cycle cost of material and equipment; optimization of industrial processes costs through material development. This paper describes the methodology used in the management of the development programs and presents some examples of concluded and ongoing programs, which are conducted in permanent cooperation with suppliers, technical laboratories and research institutions and have been showing relevant results

  14. Monthly Program Cost Report (MPCR)

    Data.gov (United States)

    Department of Veterans Affairs — The Monthly Program Cost Report (MPCR) replaces the Cost Distribution Report (CDR). The MPCR provides summary information about Veterans Affairs operational costs,...

  15. Cost analysis guidelines

    International Nuclear Information System (INIS)

    Strait, R.S.

    1996-01-01

    The first phase of the Depleted Uranium Hexafluoride Management Program (Program)--management strategy selection--consists of several program elements: Technology Assessment, Engineering Analysis, Cost Analysis, and preparation of an Environmental Impact Statement (EIS). Cost Analysis will estimate the life-cycle costs associated with each of the long-term management strategy alternatives for depleted uranium hexafluoride (UF6). The scope of Cost Analysis will include all major expenditures, from the planning and design stages through decontamination and decommissioning. The costs will be estimated at a scoping or preconceptual design level and are intended to assist decision makers in comparing alternatives for further consideration. They will not be absolute costs or bid-document costs. The purpose of the Cost Analysis Guidelines is to establish a consistent approach to analyzing of cost alternatives for managing Department of Energy's (DOE's) stocks of depleted uranium hexafluoride (DUF6). The component modules that make up the DUF6 management program differ substantially in operational maintenance, process-options, requirements for R and D, equipment, facilities, regulatory compliance, (O and M), and operations risk. To facilitate a consistent and equitable comparison of costs, the guidelines offer common definitions, assumptions or basis, and limitations integrated with a standard approach to the analysis. Further, the goal is to evaluate total net life-cycle costs and display them in a way that gives DOE the capability to evaluate a variety of overall DUF6 management strategies, including commercial potential. The cost estimates reflect the preconceptual level of the designs. They will be appropriate for distinguishing among management strategies

  16. Applied cost allocation

    DEFF Research Database (Denmark)

    Bogetoft, Peter; Hougaard, Jens Leth; Smilgins, Aleksandrs

    2016-01-01

    This paper deals with empirical computation of Aumann–Shapley cost shares for joint production. We show that if one uses a mathematical programing approach with its non-parametric estimation of the cost function there may be observations in the data set for which we have multiple Aumann–Shapley p...... of assumptions concerning firm behavior. These assumptions enable us to connect inefficient with efficient production and thereby provide consistent ways of allocating the costs arising from inefficiency....

  17. Uranium milling costs

    International Nuclear Information System (INIS)

    Coleman, R.B.

    1980-01-01

    Basic process flowsheets are reviewed for conventional milling of US ores. Capital costs are presented for various mill capacities for one of the basic processes. Operating costs are shown for various mill capacities for all of the basic process flowsheets. The number of mills using, or planning to use, a particular process is reviewed. A summary of the estimated average milling costs for all operating US mills is shown

  18. Replacement of radiography with ultrasonic phased array for feeder tubes in CANDU reactors using ASME code case N-659-2

    International Nuclear Information System (INIS)

    Simmons, R.; Bower, Q.; Arseneau, S.

    2013-01-01

    In this paper we will discuss phased array technology for the replacement of radiography on new construction projects in the nuclear industry. Specifically, through the implementation of A.S.M.E. code N-659-2 and MetaPhase phased array services. Phased Array is not considered a new technique on in service welds in the nuclear industry; however it was unprecedented on new construction welds and required significant investment in regulatory approval (C.N.S.C.), technology research and development, regulatory, client and technician training for successful service implementation. This paper will illustrate the abilities and limitations associated in replacing radiography with MetaPhase, as well as the substantial benefits relative to increased production, improved weld quality, enhanced safety and overall project cost savings. (author)

  19. Designer's unified cost model

    Science.gov (United States)

    Freeman, William T.; Ilcewicz, L. B.; Swanson, G. D.; Gutowski, T.

    1992-01-01

    A conceptual and preliminary designers' cost prediction model has been initiated. The model will provide a technically sound method for evaluating the relative cost of different composite structural designs, fabrication processes, and assembly methods that can be compared to equivalent metallic parts or assemblies. The feasibility of developing cost prediction software in a modular form for interfacing with state of the art preliminary design tools and computer aided design programs is being evaluated. The goal of this task is to establish theoretical cost functions that relate geometric design features to summed material cost and labor content in terms of process mechanics and physics. The output of the designers' present analytical tools will be input for the designers' cost prediction model to provide the designer with a data base and deterministic cost methodology that allows one to trade and synthesize designs with both cost and weight as objective functions for optimization. The approach, goals, plans, and progress is presented for development of COSTADE (Cost Optimization Software for Transport Aircraft Design Evaluation).

  20. Designers' unified cost model

    Science.gov (United States)

    Freeman, W.; Ilcewicz, L.; Swanson, G.; Gutowski, T.

    1992-01-01

    The Structures Technology Program Office (STPO) at NASA LaRC has initiated development of a conceptual and preliminary designers' cost prediction model. The model will provide a technically sound method for evaluating the relative cost of different composite structural designs, fabrication processes, and assembly methods that can be compared to equivalent metallic parts or assemblies. The feasibility of developing cost prediction software in a modular form for interfacing with state-of-the-art preliminary design tools and computer aided design programs is being evaluated. The goal of this task is to establish theoretical cost functions that relate geometric design features to summed material cost and labor content in terms of process mechanics and physics. The output of the designers' present analytical tools will be input for the designers' cost prediction model to provide the designer with a database and deterministic cost methodology that allows one to trade and synthesize designs with both cost and weight as objective functions for optimization. This paper presents the team members, approach, goals, plans, and progress to date for development of COSTADE (Cost Optimization Software for Transport Aircraft Design Evaluation).

  1. Avoidable waste management costs

    Energy Technology Data Exchange (ETDEWEB)

    Hsu, K.; Burns, M.; Priebe, S.; Robinson, P.

    1995-01-01

    This report describes the activity based costing method used to acquire variable (volume dependent or avoidable) waste management cost data for routine operations at Department of Energy (DOE) facilities. Waste volumes from environmental restoration, facility stabilization activities, and legacy waste were specifically excluded from this effort. A core team consisting of Idaho National Engineering Laboratory, Los Alamos National Laboratory, Rocky Flats Environmental Technology Site, and Oak Ridge Reservation developed and piloted the methodology, which can be used to determine avoidable waste management costs. The method developed to gather information was based on activity based costing, which is a common industrial engineering technique. Sites submitted separate flow diagrams that showed the progression of work from activity to activity for each waste type or treatability group. Each activity on a flow diagram was described in a narrative, which detailed the scope of the activity. Labor and material costs based on a unit quantity of waste being processed were then summed to generate a total cost for that flow diagram. Cross-complex values were calculated by determining a weighted average for each waste type or treatability group based on the volume generated. This study will provide DOE and contractors with a better understanding of waste management processes and their associated costs. Other potential benefits include providing cost data for sites to perform consistent cost/benefit analysis of waste minimization and pollution prevention (WMIN/PP) options identified during pollution prevention opportunity assessments and providing a means for prioritizing and allocating limited resources for WMIN/PP.

  2. Avoidable waste management costs

    International Nuclear Information System (INIS)

    Hsu, K.; Burns, M.; Priebe, S.; Robinson, P.

    1995-01-01

    This report describes the activity based costing method used to acquire variable (volume dependent or avoidable) waste management cost data for routine operations at Department of Energy (DOE) facilities. Waste volumes from environmental restoration, facility stabilization activities, and legacy waste were specifically excluded from this effort. A core team consisting of Idaho National Engineering Laboratory, Los Alamos National Laboratory, Rocky Flats Environmental Technology Site, and Oak Ridge Reservation developed and piloted the methodology, which can be used to determine avoidable waste management costs. The method developed to gather information was based on activity based costing, which is a common industrial engineering technique. Sites submitted separate flow diagrams that showed the progression of work from activity to activity for each waste type or treatability group. Each activity on a flow diagram was described in a narrative, which detailed the scope of the activity. Labor and material costs based on a unit quantity of waste being processed were then summed to generate a total cost for that flow diagram. Cross-complex values were calculated by determining a weighted average for each waste type or treatability group based on the volume generated. This study will provide DOE and contractors with a better understanding of waste management processes and their associated costs. Other potential benefits include providing cost data for sites to perform consistent cost/benefit analysis of waste minimization and pollution prevention (WMIN/PP) options identified during pollution prevention opportunity assessments and providing a means for prioritizing and allocating limited resources for WMIN/PP

  3. Rethinking sunk costs

    International Nuclear Information System (INIS)

    Capen, E.C.

    1991-01-01

    As typically practiced in the petroleum/ natural gas industry, most economic calculations leave out sunk costs. Integrated businesses can be hurt by the omission of sunk costs because profits and costs are not allocated properly among the various business segments. Not only can the traditional sunk-cost practice lead to predictably bad decisions, but a company that operates under such a policy will have no idea how to allocate resources among its operating components; almost none of its calculated returns will be correct. This paper reports that the solution is to include asset value as part of the investment in the calculation

  4. Management and cost accounting

    CERN Document Server

    Drury, Colin

    1992-01-01

    This third edition of a textbook on management and cost accounting features coverage of activity-based costing (ABC), advance manufacturing technologies (AMTs), JIT, MRP, target costing, life-cycle costing, strategic management accounting, total quality management and customer profitability analysis. Also included are revised and new end-of-chapter problems taken from past examination papers of CIMA, ACCA and ICAEW. There is increased reference to management accounting in practice, including many of the results of the author's CIMA sponsored survey, and greater emphasis on operational control and performance measurement.

  5. The COST model for calculation of forest operations costs

    NARCIS (Netherlands)

    Ackerman, P.; Belbo, H.; Eliasson, L.; Jong, de J.J.; Lazdins, A.; Lyons, J.

    2014-01-01

    Since the late nineteenth century when high-cost equipment was introduced into forestry there has been a need to calculate the cost of this equipment in more detail with respect to, for example, cost of ownership, cost per hour of production, and cost per production unit. Machine cost calculations

  6. Improving hospital cost accounting with activity-based costing.

    Science.gov (United States)

    Chan, Y C

    1993-01-01

    In this article, activity-based costing, an approach that has proved to be an improvement over the conventional costing system in product costing, is introduced. By combining activity-based costing with standard costing, health care administrators can better plan and control the costs of health services provided while ensuring that the organization's bottom line is healthy.

  7. External costs of electricity

    International Nuclear Information System (INIS)

    Rabl, A.; Spadaro, J.V.

    2005-01-01

    This article presents a synthesis of the ExternE project (External costs of Energy) of the European community about the external costs of power generation. Pollution impacts are calculated using an 'impact pathways' analysis, i.e. an analysis of the emission - dispersion - dose-response function - cost evaluation chain. Results are presented for different fuel cycles (with several technological variants) with their confidence intervals. The environmental impact costs are particularly high for coal: for instance, in France, for coal-fired power plants it is of the same order as the electricity retail price. For natural gas, this cost is about a third of the one for coal. On the contrary, the environmental impact costs for nuclear and renewable energies are low, typically of few per cent of the electricity price. The main part of these costs corresponds to the sanitary impacts, in particular the untimely mortality. In order to avoid any controversy about the cost evaluation of mortality, the reduction of the expectation of life due to the different fuel cycles is also indicated and the risks linked with nuclear energy are presented using several comparisons. (J.S.)

  8. Supply Chain Costing

    DEFF Research Database (Denmark)

    Asmussen, Jesper Normann; Kristensen, Jesper; Wæhrens, Brian Vejrum

    Based Costing (ABC) på et forsyningskædeniveau – heri benævnt Supply Chain Costing (SCC). Udoverdefordelederfindesved ABCtilføjerSCCogså et økonomisk grundlag til det strategiske rationale, der ofte ligger bag opbygningen af virksomhedens forsyningskæde, og kan dermed medvirke til konkret...

  9. Resources and transaction costs

    DEFF Research Database (Denmark)

    Foss, Kirsten; Foss, Nicolai Juul

    2005-01-01

    from resources depends on the property rights that he or she holds and on the transaction costs of exchanging, defining, and protecting them. While transaction costs are a major source of value dissipation, reducing such dissipation may create value. Implications for the RBV analysis of sustained...

  10. Resources and Transaction Costs

    DEFF Research Database (Denmark)

    Foss, Kirsten; Foss, Nicolai Juul

    2004-01-01

    resources depends on the propertyrights that she holds to those resources and on the transaction costs of exchanging,defining and protecting the relevant property rights. While transaction costs aremajor sources of value dissipation, value may be created by reducing suchdissipation. Implications for the RBV...

  11. Costs and Tariff

    Indian Academy of Sciences (India)

    ... of magnitude as construction costs. Proposed Civil Nuclear Liability Bill 2008: Reactor operators liable for accidents; must take insurance for Rs. 100-300 crores. Tariff: Despite all this, NPCIL claims it will not cost customers more than Rs. 4 per unit incl. waste disposal and decommish. It wont be easy. We wish them luck !

  12. Information at a cost

    NARCIS (Netherlands)

    Robalo, P.; Sayag, R.

    2012-01-01

    The supposed irrelevance of historical costs for rational decision making has been the subject of much interest in the economic literature. In this paper we explore whether individual decision making under risk is affected by the cost of the supplied information. Outside of the lab, it is difficult

  13. Controlling Health Care Costs

    Science.gov (United States)

    Dessoff, Alan

    2009-01-01

    This article examines issues on health care costs and describes measures taken by public districts to reduce spending. As in most companies in America, health plan designs in public districts are being changed to reflect higher out-of-pocket costs, such as higher deductibles on visits to providers, hospital stays, and prescription drugs. District…

  14. Applied cost allocation

    DEFF Research Database (Denmark)

    Bogetoft, Peter; Hougaard, Jens Leth; Smilgins, Aleksandrs

    2016-01-01

    This paper deals with empirical computation of Aumann–Shapley cost shares for joint production. We show that if one uses a mathematical programing approach with its non-parametric estimation of the cost function there may be observations in the data set for which we have multiple Aumann–Shapley p...

  15. Managing Ongoing EVSE Costs

    Energy Technology Data Exchange (ETDEWEB)

    Hodge, Cabell [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-09-05

    The costs associated with EVSE begin with picking the best location and unit for the job, but they continue with electricity and network charges through the life of your vehicle. This presentation tells how to balance electricity demand charges and network management costs through smart planning at your program's inception.

  16. Factors affecting mining costs

    International Nuclear Information System (INIS)

    Lowell, A.F.

    1977-01-01

    The subject is discussed under the following headings: investment decision-making, unit cost factors (declining ore grade, low-price contracts, ore grade/output relationship, above average cost increases). Economic, environmental, sociological and political aspects are considered. (U.K.)

  17. Networks and Transaction Costs

    DEFF Research Database (Denmark)

    Henning, Christian; Henningsen, Geraldine; Henningsen, Arne

    2011-01-01

    Based on the well-known fact that social networks can provide effective mechanisms that help to increase the trust level between two trade partners, we apply a simple game-theoretical framework to derive transaction costs as a high risk of opportunistic behavior in a repeated trade relation...... determined by the density and size of trading networks. In the empirical part of the paper we apply a two stage procedure to estimate the impact of social network structures on farm’s transaction costs observed for different input and output markets. At a first stage we estimate a multiple input...... transaction cost functions for all traded farm inputs and outputs. Estimation results based on a sample of 315 Polish farms imply a significant influence of social network structures on farm’s transaction costs. Moreover, estimated transaction costs correspond to a reasonable amount of farm specific shadow...

  18. Networks and Transaction Costs

    DEFF Research Database (Denmark)

    Henning, Christian; Henningsen, Geraldine; Henningsen, Arne

    2011-01-01

    determined by the density and size of trading networks. In the empirical part of the paper we apply a two stage procedure to estimate the impact of social network structures on farm’s transaction costs observed for different input and output markets. At a first stage we estimate a multiple input......Based on the well-known fact that social networks can provide effective mechanisms that help to increase the trust level between two trade partners, we apply a simple game-theoretical framework to derive transaction costs as a high risk of opportunistic behavior in a repeated trade relation...... transaction cost functions for all traded farm inputs and outputs. Estimation results based on a sample of 315 Polish farms imply a significant influence of social network structures on farm’s transaction costs. Moreover, estimated transaction costs correspond to a reasonable amount of farm specific shadow...

  19. COST QUALITY MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Vitanova Gordana

    2009-05-01

    Full Text Available Within the contemporary economic conditions, enterprises might achieve a competitive advantage if only they sell goods and services with high quality and lower prices. Customers, usually, prefer quality goods with acceptable prices, while such goods create reputation with the particular brand. The perfect control system is necessary to achieve a high quality product, which the cost quality management is considered to be an indispensable part in. The cost quality is nevertheless created to ensure that customers’ requirements are being appropriately attained. The most important objective of quality costs controlling is to assist the management in enhancing the product’s value permanently. The superior cost quality control system helps the management to achieve other strategic objectives, such as: producing goods with acceptable costs and deliver the products to their customers in time.

  20. Reference costs of electricity

    International Nuclear Information System (INIS)

    Terraz, N.

    1997-01-01

    The calculation of electric power production reference costs is used in France, even in the present case of over-capacity, for comparing the relative interest of the various means of power generation (nuclear plants, coal plants, hydroelectricity, gas combined cycles, etc.) and as an aid for future investment decisions. Reference costs show a sharp decrease between 1993 and 1997 due to advancements in nuclear plant operating ability and fossil fuel price decrease. Actuarial rates, plant service life, fuel costs and exchange rates are important parameters. The various costs from the research stage to the waste processing stages are discussed and the reference costs of the various power generation systems are presented and compared together with their competitiveness; the future of wind energy and cogeneration and the prospective of the renewal of nuclear plants at the 2010 horizon are also addressed

  1. Costs of Archival Storage

    DEFF Research Database (Denmark)

    Nielsen, Anders Bo; Thirifays, Alex; Kejser, Ulla Bøgvad

    2012-01-01

    to determine the costs of establishing and maintaining a preservation solution destined for long-term preservation of digital materials and to develop a tool capable of doing this operation. In order to fulfill the purposes, the project employed a combination of own and external experience as well as the OAIS......This paper presents an analysis of the cost of archival storage. The study is part of a project conducted by The Danish National Archives, The Royal Library, and The State and University Library to develop a generic cost model for digital preservation (CMDP). The purposes of the study were...... Reference Model as a framework to fully understand and identify the cost critical activities of bit-preservation as described in Archival Storage. We found that the costs of Archival Storage are obviously closely linked to the data volume, but also to the required preservation quality, especially...

  2. Transmission line capital costs

    International Nuclear Information System (INIS)

    Hughes, K.R.; Brown, D.R.

    1995-05-01

    The displacement or deferral of conventional AC transmission line installation is a key benefit associated with several technologies being developed with the support of the U.S. Department of Energy's Office of Energy Management (OEM). Previous benefits assessments conducted within OEM have been based on significantly different assumptions for the average cost per mile of AC transmission line. In response to this uncertainty, an investigation of transmission line capital cost data was initiated. The objective of this study was to develop a database for preparing preliminary estimates of transmission line costs. An extensive search of potential data sources identified databases maintained by the Bonneville Power Administration (BPA) and the Western Area Power Administration (WAPA) as superior sources of transmission line cost data. The BPA and WAPA data were adjusted to a common basis and combined together. The composite database covers voltage levels from 13.8 to 765 W, with cost estimates for a given voltage level varying depending on conductor size, tower material type, tower frame type, and number of circuits. Reported transmission line costs vary significantly, even for a given voltage level. This can usually be explained by variation in the design factors noted above and variation in environmental and land (right-of-way) costs, which are extremely site-specific. Cost estimates prepared from the composite database were compared to cost data collected by the Federal Energy Regulatory Commission (FERC) for investor-owned utilities from across the United States. The comparison was hampered because the only design specifications included with the FERC data were voltage level and line length. Working within this limitation, the FERC data were not found to differ significantly from the composite database. Therefore, the composite database was judged to be a reasonable proxy for estimating national average costs

  3. Decommissioning Unit Cost Data

    International Nuclear Information System (INIS)

    Sanford, P. C.; Stevens, J. L.; Brandt, R.

    2002-01-01

    The Rocky Flats Closure Site (Site) is in the process of stabilizing residual nuclear materials, decommissioning nuclear facilities, and remediating environmental media. A number of contaminated facilities have been decommissioned, including one building, Building 779, that contained gloveboxes used for plutonium process development but did little actual plutonium processing. The actual costs incurred to decommission this facility formed much of the basis or standards used to estimate the decommissioning of the remaining plutonium-processing buildings. Recent decommissioning activities in the first actual production facility, Building 771, implemented a number of process and procedural improvements. These include methods for handling plutonium contaminated equipment, including size reduction, decontamination, and waste packaging, as well as management improvements to streamline planning and work control. These improvements resulted in a safer working environment and reduced project cost, as demonstrated in the overall project efficiency. The topic of this paper is the analysis of how this improved efficiency is reflected in recent unit costs for activities specific to the decommissioning of plutonium facilities. This analysis will allow the Site to quantify the impacts on future Rocky Flats decommissioning activities, and to develop data for planning and cost estimating the decommissioning of future facilities. The paper discusses the methods used to collect and arrange the project data from the individual work areas within Building 771. Regression and data correlation techniques were used to quantify values for different types of decommissioning activities. The discussion includes the approach to identify and allocate overall project support, waste management, and Site support costs based on the overall Site and project costs to provide a ''burdened'' unit cost. The paper ultimately provides a unit cost basis that can be used to support cost estimates for

  4. 皮带定量给料机在配料系统中的设计实例%The design examples of belt constant tonnage feeder in ingredients system

    Institute of Scientific and Technical Information of China (English)

    严荣涛

    2011-01-01

    This paper introduces the design examples of belt constant tonnage feeder in cement production process of ingredients system, which can be used in chemical industry or other ingredients system. According to the different needs of users, experienced designers can scheme out much better design scheme optimally, and improve the design quality constantly, promote the progress of technology of ingredients.%本文介绍了皮带定量给料机在水泥生产过程的配料系统设计的一个实例,这种实用设计模式也可用于化工行业或其他配料系统。作为设计中经验丰富的设计人员会根据用户的不同需求,优化设计出更多更好的设计方案,不断提高设计质量,推动配料技术的进步。

  5. Distribución de potencia en los alimentadores de baja tensión con varios conductores por fase; Power Distribution in Low Tension Feeders with Several Phase Conductors

    Directory of Open Access Journals (Sweden)

    Héctor S Llamo Laborí

    2011-02-01

    Full Text Available En las redes de distribución a 120/208 V, las corrientes debidas a las cargas son muy altas y ello obliga ainstalar varios conductores en paralelo por fase. La mayor o menor asimetría de las corrientes que circulan porcada uno de los conductores que forman cada fase no son función del balanceo que se haga de la carga ni delmayor o menor desbalance de las tensiones sino de la disposición de las fases. En este trabajo se presentanlas características y los resultados de un algoritmo para determinar cuál es la disposición de las fases quepermiten obtener el mejor aprovechamiento de la capacidad instalada en los conductores del alimentador. In the 120/208 distribution grids, the loads currents are very high. In this case it is necessary to install severalconductors in parallel. The more o less asymmetry of currents in the different conductors that form everyphase is function of the phase disposition and not of the more or less unbalance of the tension or the loadscurrents. In this work are presented the characteristics and the results of algorithms that permit to determinewhich the phase disposition is that bring the better use of the installed capacity of the feeder.

  6. Nuclear power costs

    International Nuclear Information System (INIS)

    1963-01-01

    A report prepared by the IAEA Secretariat and presented to the seventh session of the Agency's General Conference says that information on nuclear power costs is now rapidly moving from the domain of uncertain estimates to that of tested factual data. As more and more nuclear power stations are being built and put into operation, more information on the actual costs incurred is becoming available. This is the fourth report on nuclear power costs to be submitted to the IAEA General Conference. The report last year gave cost information on 38 nuclear power projects, 17 of which have already gone into operation. Certain significant changes in the data given last year are included-in the present report; besides, information is given on seven new plants. The report is divided into two parts, the first on recent developments and current trends in nuclear power costs and the second on the use of the cost data for economic comparisons. Both stress the fact that the margin of uncertainty in the basic data has lately been drastically reduced. At the same time, it is pointed out, some degree of uncertainty is inherent in the assumptions made in arriving at over-all generating cost figures, especially when - as is usually the case - a nuclear plant is part of an integrated power system

  7. Drilling cost analysis

    International Nuclear Information System (INIS)

    Anand, A.B.

    1992-01-01

    Drilling assumes greater importance in present day uranium exploration which emphasizes to explore more areas on the basis of conceptual model than merely on surface anomalies. But drilling is as costly as it is important and consumes a major share (50% to 60%) of the exploration budget. As such the cost of drilling has great bearing on the exploration strategy as well as on the overall cost of the project. Therefore, understanding the cost analysis is very much important when planning or intensifying an exploration programme. This not only helps in controlling the current operations but also in planning the budgetary provisions for future operations. Also, if the work is entrusted to a private party, knowledge of in-house cost analysis helps in fixing the rates of drilling in different formations and areas to be drilled. Under this topic, various factors that contribute to the cost of drilling per meter as well as ways to minimize the drilling cost for better economic evaluation of mineral deposits are discussed. (author)

  8. The Cost of Astronomy

    DEFF Research Database (Denmark)

    Dorch, Bertil F.

    Using Scopus and national sources, I have investigated the evolution of the cost of publishing in Danish astronomy on a fine scale over a number of years. I find that the number of publications per year from Danish astronomers increased by a factor of four during 15 years: naturally, the correspo......Using Scopus and national sources, I have investigated the evolution of the cost of publishing in Danish astronomy on a fine scale over a number of years. I find that the number of publications per year from Danish astronomers increased by a factor of four during 15 years: naturally......, the corresponding potential cost of publishing must have increased similarly. The actual realized cost of publishing in core journals are investigated for a high profile Danish astronomy research institutions. I argue that the situation is highly unstable if the current cost scenario continues, and I speculate...... that Danish astronomy is risking a scholarly communication collapse due to the combination of increasing subscription cost, increased research output, and increased direct publishing costs related to Open access and other page charges....

  9. Nuclear power generating costs

    International Nuclear Information System (INIS)

    Srinivasan, M.R.; Kati, S.L.; Raman, R.; Nanjundeswaran, K.; Nadkarny, G.V.; Verma, R.S.; Mahadeva Rao, K.V.

    1983-01-01

    Indian experience pertaining to investment and generation costs of nuclear power stations is reviewed. The causes of investment cost increases are analysed and the increases are apportioned to escalation, design improvements and safety related adders. The paper brings out the fact that PHWR investment costs in India compare favourably with those experienced in developed countries in spite of the fact that the programme and the unit size are relatively much smaller in India. It brings out that in India at current prices a nuclear power station located over 800 km from coal reserves and operating at 75% capacity factor is competitive with thermal power at 60% capacity factor. (author)

  10. The cost of children

    DEFF Research Database (Denmark)

    Nordström, Leif Jonas

    , the opportunity cost of two children is estimated to 28-29 per cent of full income, which in monetary units is close to estimated income difference between women employed in the public and private sector. The opportunity cost of fatherhood is generally positive, but only significantly positive for men born......In this paper we estimate the opportunity cost of children. The underlying theoretical model is represented by a household production model. In the empirical analysis, we consider three different cohorts for men and women born between 1955 and 1970. For the women in the two oldest cohorts...

  11. Platform decommissioning costs

    International Nuclear Information System (INIS)

    Rodger, David

    1998-01-01

    There are over 6500 platforms worldwide contributing to the offshore oil and gas production industry. In the North Sea there are around 500 platforms in place. There are many factors to be considered in planning for platform decommissioning and the evaluation of options for removal and disposal. The environmental impact, technical feasibility, safety and cost factors all have to be considered. This presentation considers what information is available about the overall decommissioning costs for the North Sea and the costs of different removal and disposal options for individual platforms. 2 figs., 1 tab

  12. Ventilation cost and air cleaning

    Science.gov (United States)

    Goodfellow, H. D.

    The components associated with the costs of the purchase of pollution control equipment are discussed. These include the capital cost to purchase the equipment and installation, and the costs incurred to operate the control device on an annual basis. Although the capital costs can represent a significant outlay of money, typically these costs are spread out over the life of the equipment. In general, this amortized cost is combined with the operating cost and is referred to as an 'annualized cost'. The annualized cost is a commonly used indicator to demonstrate the actual year to year cost that the equipment and operation will represent. Values and methods used to estimate costs, typical cost indicators, and sources of computerized costing models are presented. A comparison of the capital cost expenditure required for a model case (a cement kiln operation), using three control device alternatives is made.

  13. Invisible costs, visible savings.

    Science.gov (United States)

    Lefever, G

    1999-08-01

    By identifying hidden inventory costs, nurse managers can save money for the organization. Some measures include tracking and standardizing supplies, accurately evaluating patients' needs, and making informed purchasing decisions.

  14. The geothermal KWh cost

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    Numerous factors can influence the cost of geothermal electricity production: the size and power of production units, the conversion technology used (Rankine cycle or water steam), the resource quality (dry vapor or water-vapor mixing), the resource depth, the drilling activity in the country and the work people costs. In the United States of America the geothermal kWh cost ranges from 2.5 to 8.5 US cents, while in Italy and Nicaragua it ranges from 3 and 10 cents and from 5.7 to 6 cents, respectively. Results of a comparative study of the kWh production cost from different energy sources is also summarized. (J.S.). 1 tab

  15. Systems/cost summary

    International Nuclear Information System (INIS)

    Grand, P.; Danby, G.; Keane, J.; Spiro, J.; Sutter, D.; Cole, F.; Hoyer, E.; Freytag, K.; Burke, R.

    1977-01-01

    The purpose of the meeting was to discuss and develop cost-estimating methods for heavy-ion fusion accelerator systems. The group did not consider that its purpose was to make technical judgements on proposed systems, but to develop methods for making reasonable cost estimates of these systems. Such estimates will, it is hoped, provide material for systems studies, will help in guiding research and development efforts by identifying ''high-leverage'' subsystems (areas that account for a significant part of total system cost and that might be reduced in cost by further technical development) and to begin to provide data to aid in an eventual decision on the optimum type of accelerator for heavy-ion fusion

  16. Systems/cost: summary

    International Nuclear Information System (INIS)

    Grand, P.; Danby, G.; Keane, J.; Spiro, J.; Sutter, D.; Cole, F.; Hoyer, E.; Freytag, K.; Burke, R.

    1978-01-01

    The purpose of the meeting was to discuss and develop cost-estimating methods for heavy-ion fusion accelerator systems. The group did not consider that its purpose was to make technical judgments on proposed systems, but to develop methods for making reasonable cost estimates of these systems. Such estimates will, it is hoped, provide material for systems studies, will help in guiding research and development efforts by identifying high-leverage subsystems (areas that account for a significant part of total system cost and that might be reduced in cost by further technical development) and to begin to provide data to aid in an eventual decision on the optimum type of accelerator for heavy-ion fusion. The systems considered as examples are: (1) injection system; (2) Wideroe linac; (3) Alvarez linac; (4) induction linac; (5) superconducting accumulator ring; (6) synchrotron; (7) final rf bunching; and (8) final beam transport to target

  17. Value and Transaction Costs

    DEFF Research Database (Denmark)

    Foss, Kirsten; Foss, Nicolai Juul

    2003-01-01

    caused by transaction costs), andnew types of resources (i.e., capture and protection capabilities), clarifies the roleof contracting in the exercise of market power, and suggests that `strategizing'and `economizing' perspectives are related to a larger extent than is normallyrecognized. Refutable......AbstractWe forge linkages between the economics of property rights (Coase, Demsetz,Cheung, Barzel) and strategic management. Property rights to resources consistof the rights to consume, obtain income from, and alienate these resources.Transaction costs are the costs of exchanging, protecting...... and capturing propertyrights. We clarify the key role of transaction costs with respect to understandingvalue creation and the limitations and opportunities of strategizing relative tocompetitive forces. The economics of property rights identifies new sources ofvalue creation (i.e., reducing the dissipation...

  18. Health Clinic Cost Reports

    Data.gov (United States)

    U.S. Department of Health & Human Services — Healthcare Cost Report Information System (HCRIS) Dataset - Independent Rural Health Clinic and Freestanding Federally Qualified Health Center (HCLINIC).This data...

  19. COST 516 Tribology Symposium

    Energy Technology Data Exchange (ETDEWEB)

    Ronkainen, H.; Holmberg, K. [eds.

    1998-11-01

    Cost 516 Tribology action is the first joint European research action focusing on tribology, which originates in the approval of its Memorandum of understanding in February 1994. The COST 516 Tribology Symposium took place in Espoo, Finland from 14th to 15th May 1998. This was the first Symposium of the COST 516 Tribology action. The large number of research contributions at the Symposium, altogether almost SO, and their scientific and technical level, is an indication of the importance and significance of tribology research. The symposium proceedings contain papers in a wide variety of subjects, covering the three categories of the COST 516 Tribology action, namely Grease lubrication (GRIT), Tribology of renewable environmentally adapted lubricants (REAL) and Coatings and surface treatments (CAST). (orig.)

  20. Costly cables; Lange Leitung

    Energy Technology Data Exchange (ETDEWEB)

    Hautmann, Daniel

    2012-08-15

    Connection of offshore wind turbines to the onshore power supply grid requires costly cables for HV DC power transmission. The technology is mature enough to enable low-loss power transmission, but construction times may last several years.

  1. Low Cost Benefit Suggestions.

    Science.gov (United States)

    Doyel, Hoyt W.; McMillan, John D.

    1980-01-01

    Outlines eight low-cost employee benefits and summarizes their relative advantages. The eight include a stock ownership program, a sick leave pool, flexible working hours, production incentives, and group purchase plans. (IRT)

  2. Costs of hospital malnutrition.

    Science.gov (United States)

    Curtis, Lori Jane; Bernier, Paule; Jeejeebhoy, Khursheed; Allard, Johane; Duerksen, Donald; Gramlich, Leah; Laporte, Manon; Keller, Heather H

    2017-10-01

    Hospital malnutrition has been established as a critical, prevalent, and costly problem in many countries. Many cost studies are limited due to study population or cost data used. The aims of this study were to determine: the relationship between malnutrition and hospital costs; the influence of confounders on, and the drivers (medical or surgical patients or degree of malnutrition) of the relationship; and whether hospital reported cost data provide similar information to administrative data. To our knowledge, the last two goals have not been studied elsewhere. Univariate and multivariate analyses were performed on data from the Canadian Malnutrition Task Force prospective cohort study combined with administrative data from the Canadian Institute for Health Information. Subjective Global Assessment was used to assess the relationship between nutritional status and length of stay and hospital costs, controlling for health and demographic characteristics, for 956 patients admitted to medical and surgical wards in 18 hospitals across Canada. After controlling for patient and hospital characteristics, moderately malnourished patients' (34% of surveyed patients) hospital stays were 18% (p = 0.014) longer on average than well-nourished patients. Medical stays increased by 23% (p = 0.014), and surgical stays by 32% (p = 0.015). Costs were, on average, between 31% and 34% (p-values < 0.05) higher than for well-nourished patients with similar characteristics. Severely malnourished patients (11% of surveyed patients) stayed 34% (p = 0.000) longer and had 38% (p = 0.003) higher total costs than well-nourished patients. They stayed 53% (p = 0.001) longer in medical beds and had 55% (p = 0.003) higher medical costs, on average. Trends were similar no matter the type of costing data used. Over 40% of patients were found to be malnourished (1/3 moderately and 1/10 severely). Malnourished patients had longer hospital stays and as a result cost more than well

  3. Cost accounting for the radiologist.

    Science.gov (United States)

    Gentili, Amilcare

    2014-05-01

    Cost accounting is the branch of managerial accounting that deals with the analysis of the costs of a product or service. This article reviews methods of classifying and allocating costs and relationships among costs, volume, and revenues. Radiology practices need to know the cost of a procedure or service to determine the selling price of a product, bid on contracts, analyze profitability, and facilitate cost control and cost reduction.

  4. The cost of electrocoagulation

    Energy Technology Data Exchange (ETDEWEB)

    Donini, J.C.; Kan, J.; Szynkarczuk, J.; Hassan, T.A.; Kar, K.L.

    1993-01-01

    Recent research has shown that electrocoagulation is suitable for separating solids from waste water. The purpose of this study is to determine whether the method is feasible economically. The cost incurred, namely energy costs and aluminum electrode consumed, during electrocoagulation experiments with kaolinite and bentonite are examined. Emphasis is placed on sodium chloride concentration, flow rate with and without recirculation, formation of passivation layers, how sodium chloride affects aluminum efficiency, and electrode efficiency. Further study is required. 8 refs., 25 figs., 9 tabs.

  5. Cost Improvement Analysis

    Science.gov (United States)

    1986-06-01

    Cc) Ul y Cli U;ra ISO or.) . ............ t cc fl .9 it it ý I oli CC) I it cli L3 I HIM .......... 114 t4l t.r IM...Burroughz Cost AFIT/LSQ AV785-6280 Curve Programs Prof. Jeff Daneman Z-100 Cost Curve ASD/ACCR AV785- 8583 Programs Capt Arthur Mills * *- PROGRAMS CONCEPT

  6. COST BM0607

    International Nuclear Information System (INIS)

    Jong, M. de

    2009-01-01

    COST is an intergovernmental framework for European Cooperation in Science and Technology, allowing the coordination of nationally-funded research on a European level. COST contributes to reducing the fragmentation in European research investments and opening the European Research Area to cooperation worldwide. COST is specifically designed to network researchers mainly within the European Union that work on a specific topic. This COST BM0607 Action on cancer therapy using innovative targeting nanomedicines is highly multidisciplinary: nuclear medicine physicians, clinical oncologists, surgeons, physicists, radiobiologists, (in)organic chemists, radiochemists, radiopharmacists, pathologists and scientists from biomics participate in it. They define innovative new targets for cancer therapy, develop lead compounds and new radiolabelled ligands as vectors, perform molecular imaging and biologic testing, develop improved software and protocols for dosimetric calculations and select new vectors for early human use. Within the COST BM0607 more than 100 scientists from 21 countries are participating to work within 5 different working groups. Working group 1 works on the establishment of Database on Molecular Targets for Targeted Radionuclide Therapy, working group 2 deals with the development and improvement of chemistry related to new molecules for targeted radionuclide therapy. Working group 3 is dedicated to dosimetry aspects, whereas working group 4 tries to optimize the use of new radionuclides for therapy from cyclotron, reactor and generator production. Finally, working group 5 has the aim to bring together research related to pharmacology and small animal imaging with new tracers for targeted radionuclide therapy. COST thereby organizes annual meetings of the whole group and in between dedicated meetings of the working groups. Besides organizing meetings one aim of COST is additionally to promote young researchers where short term scientific missions (STSM) are

  7. Cost and Price Collaboration

    Science.gov (United States)

    2016-04-30

    described below which relies on questionnaires administered to subject matter experts in both cost analysis and price analysis to determine the value of...additional reports or data that the price analyst used in determining their final negotiated position. The cost analyst section of the questionnaire...an analysis at the individual element level rather than at a total price level to determine the major changes from the awarded contract to the new

  8. Real energy cost

    International Nuclear Information System (INIS)

    Vinogradova, I.

    1992-01-01

    Different methods of calculating the real power cost in the USA taking account of damage brought to the environment, public health expenses etc., are considered. Application of complex methods allowing one to directly determine the costs linked with ecology has shown that the most expensive power is generated at the new NPPs and thermal plants using coal. Activities on power saving and increasing the capacity of the existing hydroelectrotechnical equipment are considered to be the most effective from the viewpoint of expenses

  9. Tracking environmental costs

    International Nuclear Information System (INIS)

    Blahutova, Z.

    2011-01-01

    Tracking Environmental Costs and Investments in SAP will provide us with a managerial tool that will help us understand better the magnitude of the financial resources we are dedicating to environmental protection activities and investments. Environmental Cost Accounting is a new project in Slovenske Elektrarne that will be particularly valuable for the Company's environmental management initiatives, such as waste monitoring, cleaner production, eco-design and environmental management systems; its launch is expected in September. (author)

  10. The cost of reliability

    International Nuclear Information System (INIS)

    Ilic, M.

    1998-01-01

    In this article the restructuring process under way in the US power industry is being revisited from the point of view of transmission system provision and reliability was rolled into the average cost of electricity to all, it is not so obvious how is this cost managed in the new industry. A new MIT approach to transmission pricing is here suggested as a possible solution [it

  11. Costing and competition.

    Science.gov (United States)

    Bates, K; Brignall, S

    1994-01-01

    Working for patients established a new system of contracts between providers and purchasers of healthcare, with prices based on full costs, avoiding cross-subsidization. The new regime necessitates greatly improved costing systems, to improve the efficiency of service provision by creating price competition between providers. Ken Bates and Stan Brignall argue that non-price competition also occurs, with providers 'differentiating' on quality of service/product, flexibility or innovation.

  12. Hardwood sawmill downtime costs

    Science.gov (United States)

    Jan Wiedenbeck; Kyle Blackwell

    2003-01-01

    How time flies when you don't pay attention to it. With hardwood sawmill operating costs ranging from $4 to $25 per operating minute ($95/MBF to $335/MBF) and gross profit margins ranging from $0.10/BF to $0.35/BF, five extra minutes of downtime per day will cost a sawmill that produces an average of 20,000 BF per day (5 MMBF annually) between $21 and $73 per day...

  13. National Variation in Urethroplasty Cost and Predictors of Extreme Cost: A Cost Analysis with Policy Implications

    OpenAIRE

    Harris, Catherine R.; Osterberg, E. Charles; Sanford, Thomas; Alwaal, Amjad; Gaither, Thomas W.; McAninch, Jack W.; McCulloch, Charles E.; Breyer, Benjamin N.

    2016-01-01

    To determine which factors are associated with higher costs of urethroplasty procedure and whether these factors have been increasing over time. Identification of determinants of extreme costs may help reduce cost while maintaining quality.We conducted a retrospective analysis using the 2001-2010 Healthcare Cost and Utilization Project-Nationwide Inpatient Sample (HCUP-NIS). The HCUP-NIS captures hospital charges which we converted to cost using the HCUP cost-to-charge ratio. Log cost linear ...

  14. Japanese Cost Accounting Systems - analysis of the cost accounting systems of the Japanese cost accounting standard

    OpenAIRE

    Peter, Winter

    2005-01-01

    This paper aims at providing an insight into Japanese cost accounting. Firstly, the development of cost accounting in Japan is delineated. Subsequently, the cost accounting systems codified in the Japanese cost accounting standard are analysed based on the classification according to Hoitsch/Schmitz. Lastly, a critical appraisal of the cost accounting systems of the Japanese cost accounting standard as well as a comparison to German and American cost accounting systems are conducted.

  15. New Federal Cost Accounting Regulations

    Science.gov (United States)

    Wolff, George J.; Handzo, Joseph J.

    1973-01-01

    Discusses a new set of indirect cost accounting procedures which must be followed by school districts wishing to recover any indirect costs of administering federal grants and contracts. Also discusses the amount of indirect costs that may be recovered, computing indirect costs, classifying project costs, and restricted grants. (Author/DN)

  16. Social costs of energy

    International Nuclear Information System (INIS)

    Jones, P.M.S.

    1990-01-01

    There have been many studies over the past 20 years which have looked at the environmental and other impacts of energy production, conversion and use. A number of these have attempted to put a monetary value to the external costs which are not reflected in the prices charged for energy. The topic has received increased attention recently as a direct result of the recognition of the potentially large social costs that might arise from the depletion of the ozone layer, the consequences of global warming and the continued releases of acid gases from fossil fuel combustion. The determination of external costs was attempted in the report for the European Economic Community, EUR11519, ''Social Costs of Energy Consumption'', by O Hohmeyer. Due to its official sponsorship, this report has been afforded greater respect than it deserves and is being used in some quarters to claim that the external costs of nuclear power are high relative to those of fossil fuels. The remainder of this note looks at some of the serious deficiencies of the document and why its conclusions offer no meaningful guidance to policy makers. So far as the present author is aware no serious criticism of the Hohmeyer study has previously appeared. (author)

  17. Logistics costs of the enterprise

    Directory of Open Access Journals (Sweden)

    Andrea Rosová

    2007-06-01

    Full Text Available The article describe a problem of specification and systematization of enterprise’s logistics costs. With in a growing division of labour, also logistics costs increase their part in enterprises total costs.Almost all decisions about products and production in general, influence logistics processes even logistics costs and performances.In present is not clear enough, which of the cost-particles are relevant fot logistics costs, because some of logistics cost-particles accounts within overhead are charged together with costs of other sorts.Substantive step in the process of the monitoring and evidence of logistics costs is definition of this, that costs of enterprise´s processes will be inclusive in logistics costs and determining points of contact with the others departments (acquisition, production, sale etc.. After the specification of meditation processes, there is a need to choose applicable parameters for the expression of logistics performances. Besides logistics costs is needed to know logistics performances equivalent herewith at a cost of, therefore from the control side have for enterprise bigger value indices expressive correlation costs and performances(e.g. share of logistics unit costs performance.At the proposal and evidence of logistics costs and performances is needed consistently entertain an individual conditions of enterprise. Because the area of processes included strongly affects the size of account logistics costs and its share part in total costs of enterprise. Logistics costs are flow line between economy and logistics of the enterprise.

  18. Understanding your health care costs

    Science.gov (United States)

    ... ency/patientinstructions/000878.htm Understanding your health care costs To use the sharing features on this page, ... on out-of-pocket costs. Out-of-Pocket Costs The good news is there is a limit ...

  19. Costs of electricity deregulation

    International Nuclear Information System (INIS)

    Woo, C.K.; King, M.

    2006-01-01

    The last decade has witnessed efforts throughout the world to deregulate the electricity industry, with varied results. While there have been a few qualified success stories, many challenges of deregulation have come to light. These challenges can lead to negative, even disastrous, outcomes. Based on a comprehensive literature review, this paper catalogues problems experienced in various deregulation efforts, and considers the application of the lessons learned from this history to Israel, which is considering deregulation. Failings of deregulation are found to center around the following problems: high set-up cost; complicated market design; inevitable spot price volatility; market power abuse; inefficient investment; difficulty in reducing generation cost; dysfunctional input markets; stranded cost; unequal distribution of benefits. We find that many of these problems are exacerbated by the particular circumstances faced by Israel, and advise any country or region considering deregulation to carefully consider these obstacles to success. (author)

  20. Decommissioning Cost Assessment

    International Nuclear Information System (INIS)

    Labor, Bea

    2012-03-01

    The future costs for dismantling, decommissioning and handling of associated radioactive waste of nuclear installations represents substantial liabilities. It is the generations that benefits from the use of nuclear installations that shall carry the financial burden. Nuclear waste programmes have occasionally encountered set-backs related to the trust from society. This has resulted in delayed, redirected or halted activities, which has the common denominator of costs increases. In modern democratic countries, information sharing, knowledge transfer and open communication about costs for the management of radioactive waste are prerequisites for the task to develop modern methods for public participation and thus to develop well-founded and justified confidence for further development of nuclear energy. Nuclear and radiation safety Authorities have a clear role to provide unbiased information on any health, safety, financial and environmental related issues. This task requires a good understanding of the values and opinion of the public, and especially those of the younger generation

  1. Underestimation of Project Costs

    Science.gov (United States)

    Jones, Harry W.

    2015-01-01

    Large projects almost always exceed their budgets. Estimating cost is difficult and estimated costs are usually too low. Three different reasons are suggested: bad luck, overoptimism, and deliberate underestimation. Project management can usually point to project difficulty and complexity, technical uncertainty, stakeholder conflicts, scope changes, unforeseen events, and other not really unpredictable bad luck. Project planning is usually over-optimistic, so the likelihood and impact of bad luck is systematically underestimated. Project plans reflect optimism and hope for success in a supposedly unique new effort rather than rational expectations based on historical data. Past project problems are claimed to be irrelevant because "This time it's different." Some bad luck is inevitable and reasonable optimism is understandable, but deliberate deception must be condemned. In a competitive environment, project planners and advocates often deliberately underestimate costs to help gain project approval and funding. Project benefits, cost savings, and probability of success are exaggerated and key risks ignored. Project advocates have incentives to distort information and conceal difficulties from project approvers. One naively suggested cure is more openness, honesty, and group adherence to shared overall goals. A more realistic alternative is threatening overrun projects with cancellation. Neither approach seems to solve the problem. A better method to avoid the delusions of over-optimism and the deceptions of biased advocacy is to base the project cost estimate on the actual costs of a large group of similar projects. Over optimism and deception can continue beyond the planning phase and into project execution. Hard milestones based on verified tests and demonstrations can provide a reality check.

  2. Cost Warrior Moneyball

    Science.gov (United States)

    2012-10-01

    program the money? That’s Army staff business in the franchise head shed, right? The truth is that we need to know its cost, afford- ability, and...address to an Armor War - fighting Conference, Gen. Peter Chiarelli said, “If you look at any one of these systems as an individual system, you can...tainment costs. The future ain’t what it used to be. Third, change takes time and patience. Over the past 10 years, big money has been flowing. It

  3. Reduced cost of ownership

    International Nuclear Information System (INIS)

    Wyse, W.H.; Newton, J.C.

    1995-01-01

    There is common drive throughout industry towards reduced costs of ownership of plant and equipment. Rolls-Royce and Associates Ltd. has developed the systems and expertise necessary to achieve these objectives. This Paper outlines the methods being used on existing facilities, and describes a new all embracing process called Planned Lifetime Management. This process, based on the military standard Integrated Logistic Support, ensures that all aspects of support are clearly identified at the design stage and that support is monitored to allow through-life support costs to be optimized. (author)

  4. Cost-benefit

    International Nuclear Information System (INIS)

    1975-01-01

    A critical review of the cost benefit analysis is given for the LMFBR-type reactor development program given in an environmental impact statement of AEC. Several methodological shortcomings are signalled. As compared with a HTGR-type/LWR-type mix of reactors the LMFBR-type reactor will not be competitive until the U 3 O 8 prices reach a level of $ 50/lb which is not likely to happen before the year 2020. It is recommended to review the draft of the ZEC document and include timing as one of the issues. Deferal of the LMFBR-type reactor development program if necessary will not be intolerably costly

  5. Nelson-Farrar cost indexes

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This paper discusses the Nelson-Farrar Cost Indexs. Topics covered include: economic analysis, petroleum refineries, petroleum industry, pumps, compressors, beat exchangers, cost estimation, productivity and wages

  6. NPP construction cost in Canada

    International Nuclear Information System (INIS)

    Gorshkov, A.L.

    1988-01-01

    The structure of capital costs during NPP construction in Canada is considered. Capital costs comprise direct costs (cost of the ground and ground rights, infrastructure, reactor equipment, turbogenerators, electrotechnical equipment, auxiliary equipment), indirect costs (construction equipment and services, engineering works and management services, insurance payments, freight, training, operating expenditures), capital per cents for the period of construction and cost of heavy water storages. It proceeds from the analysis of the construction cost structure for a NPP with the CANDU reactor of unit power of 515, 740 and 880 MW, that direct costs make up on the average 62%

  7. 76 FR 53378 - Cost Accounting Standards: Accounting for Insurance Costs

    Science.gov (United States)

    2011-08-26

    ... Accounting Standards: Accounting for Insurance Costs AGENCY: Cost Accounting Standards Board (Board), Office... Discontinuation of Rulemaking. SUMMARY: The Office of Federal Procurement Policy (OFPP), Cost Accounting Standards... development of an amendment to Cost Accounting Standard (CAS) 416 regarding the use of the term ``catastrophic...

  8. PV O&M Cost Model and Cost Reduction

    Energy Technology Data Exchange (ETDEWEB)

    Walker, Andy

    2017-03-15

    This is a presentation on PV O&M cost model and cost reduction for the annual Photovoltaic Reliability Workshop (2017), covering estimating PV O&M costs, polynomial expansion, and implementation of Net Present Value (NPV) and reserve account in cost models.

  9. Costs and cost-effectiveness of periviable care.

    Science.gov (United States)

    Caughey, Aaron B; Burchfield, David J

    2014-02-01

    With increasing concerns regarding rapidly expanding healthcare costs, cost-effectiveness analysis allows assessment of whether marginal gains from new technology are worth the increased costs. Particular methodologic issues related to cost and cost-effectiveness analysis in the area of neonatal and periviable care include how costs are estimated, such as the use of charges and whether long-term costs are included; the challenges of measuring utilities; and whether to use a maternal, neonatal, or dual perspective in such analyses. A number of studies over the past three decades have examined the costs and the cost-effectiveness of neonatal and periviable care. Broadly, while neonatal care is costly, it is also cost effective as it produces both life-years and quality-adjusted life-years (QALYs). However, as the gestational age of the neonate decreases, the costs increase and the cost-effectiveness threshold is harder to achieve. In the periviable range of gestational age (22-24 weeks of gestation), whether the care is cost effective is questionable and is dependent on the perspective. Understanding the methodology and salient issues of cost-effectiveness analysis is critical for researchers, editors, and clinicians to accurately interpret results of the growing body of cost-effectiveness studies related to the care of periviable pregnancies and neonates. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. Software cost estimation

    NARCIS (Netherlands)

    Heemstra, F.J.

    1992-01-01

    The paper gives an overview of the state of the art of software cost estimation (SCE). The main questions to be answered in the paper are: (1) What are the reasons for overruns of budgets and planned durations? (2) What are the prerequisites for estimating? (3) How can software development effort be

  11. Software cost estimation

    NARCIS (Netherlands)

    Heemstra, F.J.; Heemstra, F.J.

    1993-01-01

    The paper gives an overview of the state of the art of software cost estimation (SCE). The main questions to be answered in the paper are: (1) What are the reasons for overruns of budgets and planned durations? (2) What are the prerequisites for estimating? (3) How can software development effort be

  12. Containing contraceptive costs

    African Journals Online (AJOL)

    April 2015, Vol. 105, No. 4. Containing contraceptive costs. There are about 7 billion people living on our planet. In many countries resources are strained and we seek to slow down the rate of population growth. There are obviously many factors that lead to rapid population growth. Contraceptive methods are an important.

  13. Cost Is Not Everything.

    Science.gov (United States)

    Clement, Russell T.

    1985-01-01

    Reports results of survey of 21 smaller to medium-sized (50,000-200,000 volumes) libraries which was conducted to determine factors used to make selection decisions in purchase of automated turnkey systems from established vendors. Factors examined include costs, software, hardware, and vendors for parts A (actual experience) and B (hypothetical…

  14. Controlling HR Costs.

    Science.gov (United States)

    Ellig, Bruce R.

    1990-01-01

    Controlling human resources costs is critical for a competitive advantage. More money will have to be invested in education and training because of an inadequate, ill-prepared group of entry-level workers. Commitment to employees will have to be considered in relation to the increased investment in them. (JOW)

  15. The Cost of Astronomy

    DEFF Research Database (Denmark)

    Dorch, Bertil F.

    Using Scopus and national sources, I have investigated the evolution of the cost of publishing in Danish astronomy on a fine scale over a number of years. I find that the number of publications per year from Danish astronomers increased by a factor of four during 15 years: naturally, the correspo...

  16. At What Cost?

    International Development Research Centre (IDRC) Digital Library (Canada)

    1996-03-01

    Mar 1, 1996 ... The production of this monograph would not have been possible without the ... RITC also conveys its thanks to the staff of Creatrix Design Group for their ...... land area devoted to tobacco farming, employment in tobacco manufacturing, ...... cost to manufacture cigarettes, demographics (i.e., age, sex, race), ...

  17. Cost Recovery Through Depreciation.

    Science.gov (United States)

    Forrester, Robert T.; Wesolowski, Leonard V.

    1983-01-01

    The approach of adopting depreciation rather than use allowance in order to recover more accurately the cost of college buildings and equipment used on federal projects is considered. It is suggested that depreciation will offer most colleges and universities a higher annual recovery rate, and an opportunity for better facilities planning. For…

  18. Heliostat cost reduction study.

    Energy Technology Data Exchange (ETDEWEB)

    Jones, Scott A.; Lumia, Ronald. (University of New Mexico, Albuquerque, NM); Davenport, Roger (Science Applications International Corporation, San Diego, CA); Thomas, Robert C. (Advanced Thermal Systems, Centennial, CO); Gorman, David (Advanced Thermal Systems, Larkspur, CO); Kolb, Gregory J.; Donnelly, Matthew W.

    2007-06-01

    Power towers are capable of producing solar-generated electricity and hydrogen on a large scale. Heliostats are the most important cost element of a solar power tower plant. Since they constitute {approx} 50% of the capital cost of the plant it is important to reduce heliostat cost as much as possible to improve the economic performance of power towers. In this study we evaluate current heliostat technology and estimate a price of $126/m{sup 2} given year-2006 materials and labor costs for a deployment of {approx}600 MW of power towers per year. This 2006 price yields electricity at $0.067/kWh and hydrogen at $3.20/kg. We propose research and development that should ultimately lead to a price as low as $90/m{sup 2}, which equates to $0.056/kWh and $2.75/kg H{sup 2}. Approximately 30 heliostat and manufacturing experts from the United States, Europe, and Australia contributed to the content of this report during two separate workshops conducted at the National Solar Thermal Test Facility.

  19. Sustainability at no Cost

    DEFF Research Database (Denmark)

    Nørgaard, Jørgen

    The presentation is dealing with some basic concept around the whole economy, and what are really the costs and the benefits. A distinction is made between professional economy, driven by money (GDP), and the amateur economy, driven by love, affection, etc. within the families, among friends, in ...

  20. [Costing nuclear medicine diagnostic procedures].

    Science.gov (United States)

    Markou, Pavlos

    2005-01-01

    To the Editor: Referring to a recent special report about the cost analysis of twenty-nine nuclear medicine procedures, I would like to clarify some basic aspects for determining costs of nuclear medicine procedure with various costing methodologies. Activity Based Costing (ABC) method, is a new approach in imaging services costing that can provide the most accurate cost data, but is difficult to perform in nuclear medicine diagnostic procedures. That is because ABC requires determining and analyzing all direct and indirect costs of each procedure, according all its activities. Traditional costing methods, like those for estimating incomes and expenses per procedure or fixed and variable costs per procedure, which are widely used in break-even point analysis and the method of ratio-of-costs-to-charges per procedure may be easily performed in nuclear medicine departments, to evaluate the variability and differences between costs and reimbursement - charges.

  1. Cost management of golf courses

    OpenAIRE

    Černický, Marek

    2010-01-01

    The thesis focuses on costs incurred during the golf course construction and also on operating costs. Types of these costs and options of cost cutting are described. The final part of the thesis analyzes and models usage yield and capacity of golf courses.

  2. Costly location in Hotelling duopoly

    NARCIS (Netherlands)

    Hinloopen, J.; Martin, S.

    2013-01-01

    We introduce a cost of location into Hotelling’s (1929) spatial duopoly. We derive the general conditions on the cost-of-location function under which a pure strategy price-location Nash equilibrium exists. With linear transportation cost and a suitably specified cost of location that rises toward

  3. Lifetime costs of cerebral palsy

    DEFF Research Database (Denmark)

    Kruse, Marie; Michelsen, Susan Ishøy; Flachs, Esben Meulengracht

    2009-01-01

    This study quantified the lifetime costs of cerebral palsy (CP) in a register-based setting. It was the first study outside the US to assess the lifetime costs of CP. The lifetime costs attributable to CP were divided into three categories: health care costs, productivity costs, and social costs....... social care costs and productivity costs associated with CP point to a potential gain from labour market interventions that benefit individuals with CP.......This study quantified the lifetime costs of cerebral palsy (CP) in a register-based setting. It was the first study outside the US to assess the lifetime costs of CP. The lifetime costs attributable to CP were divided into three categories: health care costs, productivity costs, and social costs...... in 2000. The prevalence of CP in eastern Denmark was approximately 1.7 per 1000. Information on productivity and the use of health care was retrieved from registers. The lifetime cost of CP was about euro860 000 for men and about euro800 000 for women. The largest component was social care costs...

  4. Costly location in Hotelling duopoly

    NARCIS (Netherlands)

    Hinloopen, J.; Martin, S.

    We introduce a cost of location into Hotelling's (1929) spatial duopoly model. We derive the general conditions on the cost-of-location function under which a pure strategy price-location Nash equilibrium exists. With linear transportation cost and a suitably specified cost of location that rises

  5. Production cost methods and data

    Science.gov (United States)

    Jeffe, R. E.; Fujita, T.

    1975-01-01

    The general gas cost equation for utility financing is presented. Modifications and assumptions made in order to apply the cost equation to hydrogen production are described. Cost data are given for various methods of hydrogen production. The cost matrix procedure is briefly discussed.

  6. Cost Accounting for Decision Makers.

    Science.gov (United States)

    Kaneklides, Ann L.

    1985-01-01

    Underscores the importance of informed decision making through accurate anticipation of cost incurrence in light of changing economic and environmental conditions. Explains the concepts of cost accounting, full allocation of costs, the selection of an allocation base, the allocation of indirect costs, depreciation, and implications for community…

  7. The Ethos of Cost Management

    Directory of Open Access Journals (Sweden)

    Sorinel Capusneanu

    2008-05-01

    Full Text Available This article describes the ethos of cost management, distinguishing the definition, functions and principles governing cost management. I have emphasized the efforts made by the specialists in the field towards finding a much more complete definition of cost management. The description of cost management principles reveals the current interest of the specialists in this extremely important domain of company management.

  8. MCU-Based Solar Powered Chicken Feeder

    Directory of Open Access Journals (Sweden)

    Elenor M. Reyes

    2015-12-01

    Full Text Available Poultry is a great potential industry particularly in Batangas Province. The method of feeding chicken needs to be considered as chicken must be fed regularly to be more productive. The conventional method of feeding chicken is the need to continuously provide the food, be alert and conscious on the food remaining in cages and to feed the chickens in a correct period of time to avoid the decline of the production. Growers also find it difficult to manage their businesses effectively because they need to be around the cages every now and then to monitor the poultry. Timing and exactness are the key to provide a uniform time in feeding the chickens. This will benefit the owner of the business in terms of time and effort. Another advantage of this project is in terms of savings to the owner of the poultry business. This technology was designed to automatically feed chickens at a given period of time and to give alarm when the feeds are running out of supply. The power to be supplied to this prototype will be drawn from the sun by means of solar panels and will be stored in typical car battery. The feeds will be stored in a container and evenly distributed by using a conveyor to the feeding basin of the poultry. It will be more efficient than manual conventional way of feeding because less effort will be needed in feeding the chickens and less feeds will be wasted. In addition to that, the stored power can also be used for lighting purposes for the growers to save energy and energy bills.

  9. Bats, Blood-Feeders and Biodiversity

    DEFF Research Database (Denmark)

    Bohmann, Kristine

    DNA metabarcoding of environmental samples has rapidly become a valuable tool for ecological studies such as biodiversity and diet studies. To reveal the diversity in environmental samples such as soil, water, and faeces, this approach principally employs PCR amplification of environmental DNA...... minimising the occurrence of errors. Centered around metabarcoding dietary studies of bat droppings and leech gut contents, this continuous exploration and refinement is reflected in both the work and structure of this thesis. After a thesis introduction and two chapters on environmental DNA and biodiversity...

  10. Advanced feeder control using fast simulation models

    NARCIS (Netherlands)

    Verheijen, O.S.; Op den Camp, O.M.G.C.; Beerkens, R.G.C.; Backx, A.C.P.M.; Huisman, L.; Drummond, C.H.

    2005-01-01

    For the automatic control of glass quality in glass production, the relation between process variable and product or glass quality and process conditions/process input parameters must be known in detail. So far, detailed 3-D glass melting simulation models were used to predict the effect of process

  11. Coherence-Multiplexed Optical RF Feeder Networks

    NARCIS (Netherlands)

    Meijerink, Arjan; Taniman, R.O.; van Etten, Wim

    2007-01-01

    An optical RF feeding system for wireless access is proposed, in which the radio access points are distinguished by means of coherence multiplexing (CM). CM is a rather unknown and potentially inexpensive optical code division multiple access technique, which is particularly suitable for relatively

  12. Training gilts to use a feeder station

    NARCIS (Netherlands)

    Vermeer, H.M.; Kiezebrink, M.C.; Werf, van der J.T.N.; Spoolder, H.A.M.

    2009-01-01

    Group housing of dry sows is compulsory in Europe from 2013 onwards. Many pig farmers who still have to convert to group housing fear the resulting demand on their ability to interact with individual animals. An example of such interaction is the training of gilts to use economically attractive but

  13. Nuclear power production costs

    International Nuclear Information System (INIS)

    Erramuspe, H.J.

    1988-01-01

    The economic competitiveness of nuclear power in different highly developed countries is shown, by reviewing various international studies made on the subject. Generation costs (historical values) of Atucha I and Embalse Nuclear Power Plants, which are of the type used in those countries, are also included. The results of an international study on the economic aspects of the back end of the nuclear fuel cycle are also reviewed. This study shows its relatively low incidence in the generation costs. The conclusion is that if in Argentina the same principles of economic racionality were followed, nuclear energy would be economically competitive in the future, as it is today. This is of great importance in view of its almost unavoidable character of alternative source of energy, and specially since we have to expect an important growth in the consumption of electricity, due to its low share in the total consumption of energy, and the low energy consumption per capita in Argentina. (Author) [es

  14. Costs of climate impacts

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, W O

    1980-03-01

    The surest prospect for future world climate patterns is that they will differ from present ones. What is uncertain is how much, and exactly in what way in different geographical regions. The anthropogenic CO/sub 2/ increase will probably exceed the unknown forcing functions of natural climate change within 30 to 60 years. It is not unlikely that by AD 2040 the world's climate, driven by the CO/sub 2/ increase, will enter a domain warmer than any within the past few million years. The costs of averting this climate change or of absorbing its impact are likely to be huge, even though today imponderable. Not least among these are intangible and unquantifiable costs associated with changes in human values and the quality of everyday life for future generations.

  15. Information security cost management

    CERN Document Server

    Bazavan, Ioana V

    2006-01-01

    While information security is an ever-present challenge for all types of organizations today, most focus on providing security without addressing the necessities of staff, time, or budget in a practical manner.Information Security Cost Management offers a pragmatic approach to implementing information security, taking budgetary and real-world constraints into consideration. By providing frameworks, step-by-step processes, and project management breakdowns, this book demonstrates how to design the best security strategy with the resources you have available. Organized into five sections, the book-Focuses on setting the right road map so that you can be most effective in your information security implementationsDiscusses cost-effective staffing, the single biggest expense to the security organizationPresents practical ways to build and manage the documentation that details strategy, provides resources for operating annual audits, and illustrates how to advertise accomplishments to senior management effectivelyI...

  16. Cost-of-illness studies.

    Science.gov (United States)

    Oderda, Gary M

    2003-01-01

    Cost-of-illness studies measure the overall economic impact of a disease on society. Such studies are important in setting public health priorities and for economic evaluation of new treatments. These studies should take the societal perspective and include both direct and indirect costs. Often indirect costs exceed direct costs. Comparison of cost-of-illness studies from different countries is difficult because of differences in population, currency, the way health care is provided, and other social and political factors.

  17. Phenotypic plasticity, costs of phenotypes, and costs of plasticity

    DEFF Research Database (Denmark)

    Callahan, Hilary S; Maughan, Heather; Steiner, Uli

    2008-01-01

    Why are some traits constitutive and others inducible? The term costs often appears in work addressing this issue but may be ambiguously defined. This review distinguishes two conceptually distinct types of costs: phenotypic costs and plasticity costs. Phenotypic costs are assessed from patterns...... of covariation, typically between a focal trait and a separate trait relevant to fitness. Plasticity costs, separable from phenotypic costs, are gauged by comparing the fitness of genotypes with equivalent phenotypes within two environments but differing in plasticity and fitness. Subtleties associated with both...... types of costs are illustrated by a body of work addressing predator-induced plasticity. Such subtleties, and potential interplay between the two types of costs, have also been addressed, often in studies involving genetic model organisms. In some instances, investigators have pinpointed the mechanistic...

  18. The Costs of Depression

    OpenAIRE

    Kessler, Ronald C.

    2011-01-01

    Data are reviewed on the societal costs of major depressive disorder (MDD). Early-onset MDD is found to predict difficulties in subsequent role transitions, including low educational attainment, high risk of teen child-bearing, marital disruption, and unstable employment. Among people with specific social and productive roles, MDD is found to predict significant decrements in role functioning (e.g., low marital quality, low work performance, low earnings). MDD is also associated with elevated...

  19. Geothermal probabilistic cost study

    Energy Technology Data Exchange (ETDEWEB)

    Orren, L.H.; Ziman, G.M.; Jones, S.C.; Lee, T.K.; Noll, R.; Wilde, L.; Sadanand, V.

    1981-08-01

    A tool is presented to quantify the risks of geothermal projects, the Geothermal Probabilistic Cost Model (GPCM). The GPCM model is used to evaluate a geothermal reservoir for a binary-cycle electric plant at Heber, California. Three institutional aspects of the geothermal risk which can shift the risk among different agents are analyzed. The leasing of geothermal land, contracting between the producer and the user of the geothermal heat, and insurance against faulty performance are examined. (MHR)

  20. Decreasing Serial Cost Sharing

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Østerdal, Lars Peter

    The increasing serial cost sharing rule of Moulin and Shenker [Econometrica 60 (1992) 1009] and the decreasing serial rule of de Frutos [Journal of Economic Theory 79 (1998) 245] have attracted attention due to their intuitive appeal and striking incentive properties. An axiomatic characterization...... of the increasing serial rule was provided by Moulin and Shenker [Journal of Economic Theory 64 (1994) 178]. This paper gives an axiomatic characterization of the decreasing serial rule...

  1. Decreasing serial cost sharing

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Østerdal, Lars Peter Raahave

    2009-01-01

    The increasing serial cost sharing rule of Moulin and Shenker (Econometrica 60:1009-1037, 1992) and the decreasing serial rule of de Frutos (J Econ Theory 79:245-275, 1998) are known by their intuitive appeal and striking incentive properties. An axiomatic characterization of the increasing serial...... rule was provided by Moulin and Shenker (J Econ Theory 64:178-201, 1994). This paper gives an axiomatic characterization of the decreasing serial rule....

  2. Radiation: cost or benefit?

    International Nuclear Information System (INIS)

    Crouch, D.

    1988-01-01

    In a previous issue of SCRAM it was argued that the apparent increased incidence of child leukaemia around nuclear power stations could have been caused by radioactive discharges into the environment. The National Radiological Protection Board (NRPB) claim that the known levels of contamination could not be responsible for the observed cancer rates. NRPB estimates of radiation risk are, however, considered to be underestimates. The NRPB is criticised for its study of the Sellafield workforce which excluded ex-employees and which revealed, when a statistical mistake was put right, a significant excess of myeloma amongst the Windscale workforce. The radiation protection philosophy of the NRPB is based on a cost benefit analysis which balances the cost of protection against the benefits of power generation. Criticism is made of NRPB, not only for ignoring long-term risks and costs but also for suggesting that some levels of radiation exposure are acceptable. The Board is also accused of not being independent of the nuclear industry. (UK)

  3. Power plant removal costs

    International Nuclear Information System (INIS)

    Ferguson, J.S.

    1998-01-01

    The financial, regulatory and political significance of the estimated high removal costs of nuclear power plants has generated considerable interest in recent years, and the political significance has resulted in the Nuclear Regulatory Commission (NRC) eliminating the use of conventional depreciation accounting for the decontamination portion of the removal (decommissioning). While nuclear plant licensees are not precluded from utilizing conventional depreciation accounting for the demolition of non-radioactive structures and site restoration, state and federal utility regulators have not been favorably inclined to requests for this distinction. The realization that steam-generating units will be more expensive to remove, relative to their original cost, predates the realization that nuclear units will be expensive. However, the nuclear issues have overshadowed this realization, but are unlikely to continue to do so. Numerous utilities have prepared cost estimates for steam generating units, and this presentation discusses the implications of a number of such estimates that are a matter of public record. The estimates cover nearly 400 gas, oil, coal and lignite generating units. The earliest estimate was made in 1978, and for analysis purposes the author has segregated them between gas and oil units, and coal and lignite units

  4. Proposed reliability cost model

    Science.gov (United States)

    Delionback, L. M.

    1973-01-01

    The research investigations which were involved in the study include: cost analysis/allocation, reliability and product assurance, forecasting methodology, systems analysis, and model-building. This is a classic example of an interdisciplinary problem, since the model-building requirements include the need for understanding and communication between technical disciplines on one hand, and the financial/accounting skill categories on the other. The systems approach is utilized within this context to establish a clearer and more objective relationship between reliability assurance and the subcategories (or subelements) that provide, or reenforce, the reliability assurance for a system. Subcategories are further subdivided as illustrated by a tree diagram. The reliability assurance elements can be seen to be potential alternative strategies, or approaches, depending on the specific goals/objectives of the trade studies. The scope was limited to the establishment of a proposed reliability cost-model format. The model format/approach is dependent upon the use of a series of subsystem-oriented CER's and sometimes possible CTR's, in devising a suitable cost-effective policy.

  5. Systematization of Cost Factors for Cost Management at Industrial Enterprises

    Directory of Open Access Journals (Sweden)

    N. Y.

    2017-12-01

    Full Text Available Identification and structuring of factors determining the cost level has significant importance in cost analysis and control. Cost factors need to be systematized for more effective cost management. The objective of the study is to identify and structure the factors with impact on the enterprise costs. The external and internal factors with impact on the enterprise costs in industry are highlighted. For cost management purposes, it is proposed to group the cost factors into the two categories: structural and functional. The essence of structural and functional factors is shown; a classification of functional factors is given. The effect of a structural factor such as products range (complexity is illustrated. As the factor of complexity, combined with cost analysis systems and innovative tools of analysis (ABC and XYZ methods, has been increasingly in focus of analysts, three problems are described which, once dealt with, will enable ABC method to fit into the cost management system. The importance of another structural factor of costs, technology selection, in cost management is shown. The analysis allows for the following conclusions: for purposes of current cost management, including one based on operational analysis, the output needs to be addressed as the central factor determining the cost level; in the strategic perspective, an enterprise needs to concentrate on calculating the costs for the structural alternatives that are supposed to determine its competitive position; for cost management purposes, the cost factors should be broken into two categories, structural and functional; a specific management system exists for each cost factor, which is greatly important for the positioning of an enterprise.

  6. [Operating cost analysis of anaesthesia: activity based costing (ABC analysis)].

    Science.gov (United States)

    Majstorović, Branislava M; Kastratović, Dragana A; Vučović, Dragan S; Milaković, Branko D; Miličić, Biljana R

    2011-01-01

    Cost of anaesthesiology represent defined measures to determine a precise profile of expenditure estimation of surgical treatment, which is important regarding planning of healthcare activities, prices and budget. In order to determine the actual value of anaestesiological services, we started with the analysis of activity based costing (ABC) analysis. Retrospectively, in 2005 and 2006, we estimated the direct costs of anestesiological services (salaries, drugs, supplying materials and other: analyses and equipment.) of the Institute of Anaesthesia and Resuscitation of the Clinical Centre of Serbia. The group included all anesthetized patients of both sexes and all ages. We compared direct costs with direct expenditure, "each cost object (service or unit)" of the Republican Healthcare Insurance. The Summary data of the Departments of Anaesthesia documented in the database of the Clinical Centre of Serbia. Numerical data were utilized and the numerical data were estimated and analyzed by computer programs Microsoft Office Excel 2003 and SPSS for Windows. We compared using the linear model of direct costs and unit costs of anaesthesiological services from the Costs List of the Republican Healthcare Insurance. Direct costs showed 40% of costs were spent on salaries, (32% on drugs and supplies, and 28% on other costs, such as analyses and equipment. The correlation of the direct costs of anaestesiological services showed a linear correlation with the unit costs of the Republican Healthcare Insurance. During surgery, costs of anaesthesia would increase by 10% the surgical treatment cost of patients. Regarding the actual costs of drugs and supplies, we do not see any possibility of costs reduction. Fixed elements of direct costs provide the possibility of rationalization of resources in anaesthesia.

  7. THE COST OF PRODUCTION UNDER DIRECT COSTING AND ABSORPTION COSTING – A COMPARATIVE APPROACH

    Directory of Open Access Journals (Sweden)

    Bunea-Bontaş Cristina Aurora

    2013-04-01

    Full Text Available Managerial accounting has an important role in strategic management of a company, being designed especially for managers, in order to optimise their decision regarding operating activities. One of the objectives of managerial accounting is the cost calculation, for measuring inventory costs, and the costs and profitability of products and services. Cost calculation systems can vary in terms of which costs are assigned to cost objects, two significant calculation systems being adopted by the costing theory: full cost accounting, which includes all costs of production as product costs, and partial cost accounting, which includes only those costs that vary with output. This article provides a comparative approach regarding the differences between the calculation of the cost of production under direct costing and absorption costing. It also examines the implication of using each of these calculation systems on the financial position and financial performance of the companies reported on the statement of financial position and the income statement. Finally, the advantages of using direct costing for internal reporting are discussed, considering that this method is not acceptable for external reporting to stockholders and other external users.

  8. Hidden costs of low-cost screening mammography

    International Nuclear Information System (INIS)

    Cyrlak, D.

    1987-01-01

    Twenty-two hundred women in Orange County, California, took part in a low-cost mammography screening project sponsored by the American Cancer Society and the KCBS-TV. Patients were followed up by telephone and questioned about actual costs incurred as a result of screening mammography, including costs of repeated and follow-up mammograms, US examinations and surgical consultations. The total number of biopsies, cancers found, and the costs involved were investigated. The authors' results suggest that particularly in centers with a high positive call rate, the cost of screening mammograms accounts for only a small proportion of the medical costs

  9. Propuesta del programaS-GeMS para el análisis estadístico espacial de fallas en alimentadores soterrados de 13,8 kV; PropodedS-GEMS program for statistical analysis of failure space of 13.8 kV underground feeders

    Directory of Open Access Journals (Sweden)

    Boris Alba Valle

    2011-06-01

    Full Text Available Actualmente, el sistema soterrado de Ciudad de La Habana, carece de herramientas gráficas de trabajo con lascuales poder visualizar zonas con alta incidencia de fallas en alimentadores de 13,8 kV y que permitan tomardecisiones certeras en cuanto a los tramos de alimentadores a reparar o sustituir por su deterioro. En este trabajo sepropone el uso de los programas S-GeMS (Stanford Geostatistical Modeling Software y Autocad comoherramientas para el análisis estadístico espacial de la cantidad de fallas. Se realiza, en lo fundamental, el estudiode toda la documentación referente a las aplicaciones del programa S-GeMS y la Base de Datos de la cantidad defallas del 2007 al 2009, de los alimentadores de 13,8 kV perteneciente a la Unidad Empresarial Básica (UEBSoterrada. Finalmente se muestran, a modo de ejemplo, los resultados obtenidos con su aplicación al determinarsela dirección preferencial de distribución de la cantidad de fallas.   Nowadays, the Havana City underground system, lacks of graphical working tools which not only allow to visualizehigh faults incidence areas in 13,8 kV feeders but also make good decisions in reference to the feeder sections to berepaired or substituted due to their impairment. The use of S-GeMS (Stanford Geostatistical Modeling Software andAutocad programs as tools for the spatial statistic analysis of faults quantity is proposed in this article. The study ofthe whole documentation related to the S-GeMS program applications is carried out as well as the UndergroundManagement Basic Unit (UEB 13,8 kV feeders faults quantity database from 2007 to 2009. Finally, the results afterdetermining the faults quantity distribution preferential address with the program application are shown, as anexample.

  10. Propuesta del programa S-GeMS para el análisis estadístico espacial de fallas en alimentadores soterrados de 13,8 kV;PropodedS-GEMS program for statistical analysis of failure space of 13.8 kV underground feeders

    Directory of Open Access Journals (Sweden)

    Boris Alba - Valle

    2011-06-01

    Full Text Available Actualmente, el sistema soterrado de Ciudad de La Habana, carece de herramientas gráficas de trabajo con lascuales poder visualizar zonas con alta incidencia de fallas en alimentadores de 13,8 kV y que permitan tomardecisiones certeras en cuanto a los tramos de alimentadores a reparar o sustituir por su deterioro. En este trabajo sepropone el uso de los programas S-GeMS (Stanford Geostatistical Modeling Software y Autocad comoherramientas para el análisis estadístico espacial de la cantidad de fallas. Se realiza, en lo fundamental, el estudiode toda la documentación referente a las aplicaciones del programa S-GeMS y la Base de Datos de la cantidad defallas del 2007 al 2009, de los alimentadores de 13,8 kV perteneciente a la Unidad Empresarial Básica (UEBSoterrada. Finalmente se muestran, a modo de ejemplo, los resultados obtenidos con su aplicación al determinarsela dirección preferencial de distribución de la cantidad de fallas.Nowadays, the Havana City underground system, lacks of graphical working tools which not only allow to visualizehigh faults incidence areas in 13,8 kV feeders but also make good decisions in reference to the feeder sections to berepaired or substituted due to their impairment. The use of S-GeMS (Stanford Geostatistical Modeling Software andAutocad programs as tools for the spatial statistic analysis of faults quantity is proposed in this article. The study ofthe whole documentation related to the S-GeMS program applications is carried out as well as the UndergroundManagement Basic Unit (UEB 13,8 kV feeders faults quantity database from 2007 to 2009. Finally, the results afterdetermining the faults quantity distribution preferential address with the program application are shown, as anexample.

  11. An Insight Into the Two Costing Technique: Absorption Costing and Marginal Costing

    OpenAIRE

    Mariam Nawaz

    2013-01-01

    This paper will investigate the controversy that is innate between the two costing techniques; Absorption Costing and Marginal Costing and would throw light on which costing technique better serves its purpose in helping management for decision making process and if Marginal Costing technique is concluded as better technique then why it should not be used for external reporting purpose. This paper will only crystallize and highlight the issues descriptively and will not resolve the issues tha...

  12. Tax compliance costs: A review of cost burdens and cost structures

    OpenAIRE

    Eichfelder, Sebastian; Vaillancourt, François

    2014-01-01

    Our paper provides a comprehensive report of empirical research on tax compliance costs. Compared to previous reviews, our focus is on average costs for sub-groups (individual taxpayers, small business-es, large businesses) and the composition of the cost burden with regards to different cost components(in-house time effort, external adviser costs, other monetary expenses), different taxes (e.g. income tax, value added tax) and different activities like tax accounting and tax planning. In add...

  13. Costing bias in economic evaluations.

    Science.gov (United States)

    Frappier, Julie; Tremblay, Gabriel; Charny, Mark; Cloutier, L Martin

    2015-01-01

    Determining the cost-effectiveness of healthcare interventions is key to the decision-making process in healthcare. Cost comparisons are used to demonstrate the economic value of treatment options, to evaluate the impact on the insurer budget, and are often used as a key criterion in treatment comparison and comparative effectiveness; however, little guidance is available to researchers for establishing the costing of clinical events and resource utilization. Different costing methods exist, and the choice of underlying assumptions appears to have a significant impact on the results of the costing analysis. This editorial describes the importance of the choice of the costing technique and it's potential impact on the relative cost of treatment options. This editorial also calls for a more efficient approach to healthcare intervention costing in order to ensure the use of consistent costing in the decision-making process.

  14. The costs of nuclear power

    International Nuclear Information System (INIS)

    Vestenhaug, O.; Sauar, T.O.; Nielsen, P.O.

    1979-01-01

    A study has been made by Scandpower A/S of the costs of nuclear power in Sweden. It is based on the known costs of existing Swedish nuclear power plants and forecasts of the expected costs of the Swedish nuclear power programme. special emphasis has been put on the fuel cycle costs and future costs of spent fuel processing, waste disposal and decommissioning. Costs are calculated in 1978 Swedish crowns, using the retail price index. An actual interest rate of 4% is used, with depreciation period of 25 years and a plant lifetime of 30 years. Power production costs are estimated to be about 7.7 oere/kWh in 1978, rising to 10.5 oere/kWh in 2000. The cost is distributed with one third each to capital costs, operating costs and fuel costs, the last rising to 40% of the total at the end of the century. The main single factor in future costs is the price of uranium. If desired, Sweden can probably be self-sufficient in uranium in 2000 at a lower cost than assumed here. National research costs which, in Scandpower's opinion, can be debited to the commercial nuclear power programme are about 0.3 oere/kWh. (JIW)

  15. Cost Model for Digital Preservation: Cost of Digital Migration

    DEFF Research Database (Denmark)

    Kejser, Ulla Bøgvad; Nielsen, Anders Bo; Thirifays, Alex

    2011-01-01

    The Danish Ministry of Culture has funded a project to set up a model for costing preservation of digital materials held by national cultural heritage institutions. The overall objective of the project was to increase cost effectiveness of digital preservation activities and to provide a basis...... for comparing and estimating future cost requirements for digital preservation. In this study we describe an activity-based costing methodology for digital preservation based on the Open Archice Information System (OAIS) Reference Model. Within this framework, which we denote the Cost Model for Digital...... Preservation (CMDP), the focus is on costing the functional entity Preservation Planning from the OAIS and digital migration activities. In order to estimate these costs we have identified cost-critical activities by analysing the functions in the OAIS model and the flows between them. The analysis has been...

  16. Designing Cost-Competitive Technology Products through Cost Management

    NARCIS (Netherlands)

    Davila, T.; Wouters, Marc

    2004-01-01

    SYNOPSIS: As manufacturing innovations spread throughout leading organizations, product development becomes a more important source of competitive advantage. Within product development, cost management receives increasing attention. To date, cost management in new product development focuses

  17. LIFE Cost of Electricity, Capital and Operating Costs

    International Nuclear Information System (INIS)

    Anklam, T.

    2011-01-01

    Successful commercialization of fusion energy requires economic viability as well as technical and scientific feasibility. To assess economic viability, we have conducted a pre-conceptual level evaluation of LIFE economics. Unit costs are estimated from a combination of bottom-up costs estimates, working with representative vendors, and scaled results from previous studies of fission and fusion plants. An integrated process model of a LIFE power plant was developed to integrate and optimize unit costs and calculate top level metrics such as cost of electricity and power plant capital cost. The scope of this activity was the entire power plant site. Separately, a development program to deliver the required specialized equipment has been assembled. Results show that LIFE power plant cost of electricity and plant capital cost compare favorably to estimates for new-build LWR's, coal and gas - particularly if indicative costs of carbon capture and sequestration are accounted for.

  18. Cost of mining Eastern coal

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    This paper, Chapter 7.2.3 of the 'surface mining' reference book, gives an example of how the cost of mining a ton of coal is calculated. Conditions set down are for a coal tract of 50.6 ha in West Virginia, USA to be mined by the contour surface method, the seam being 101.6cm thick. Elements of the costing are: permitting and bonding costs, engineering and construction costs, equipment and other operating expenses (such as hauling and wheeling), royalties, direct taxes and fees, costs of revegetation, and employment costs (payroll and medical expenses). 5 tabs

  19. Optimization of Human NK Cell Manufacturing: Fully Automated Separation, Improved Ex Vivo Expansion Using IL-21 with Autologous Feeder Cells, and Generation of Anti-CD123-CAR-Expressing Effector Cells.

    Science.gov (United States)

    Klöß, Stephan; Oberschmidt, Olaf; Morgan, Michael; Dahlke, Julia; Arseniev, Lubomir; Huppert, Volker; Granzin, Markus; Gardlowski, Tanja; Matthies, Nadine; Soltenborn, Stephanie; Schambach, Axel; Koehl, Ulrike

    2017-10-01

    The administration of ex vivo expanded natural killer (NK) cells as potential antitumor effector cells appears to be suitable for effector cell-based immunotherapies in high-risk cancer patients. However, good manufacturing practice (GMP)-compliant manufacturing of clinical-grade NK cells at sufficiently high numbers represents a great challenge. Therefore, previous expansion protocols for those effector cells were improved and optimized by using newly developed culture medium, interleukin (IL)-21, and autologous feeder cells (FCs). Separation of primary human NK cells (CD56 + CD3 - ) was carried out with the CliniMACS Prodigy ® in a single process, starting with approximately 1.2 × 10 9 leukocytes collected by small-scale lymphapheresis or from buffy coats. Enriched NK cells were adjusted to starting cell concentrations within approximately 1 × 10 6 effector cells/mL and cultured in comparative expansion experiments for 14 days with IL-2 (1,000 IU/mL) in different GMP-compliant media (X-VIVO ™ 10, CellGro ® , TexMACS ™ , and NK MACS ® ). After medium optimization, beneficial effects for functionality and phenotype were investigated at the beginning of cell expansion with irradiated (25 Gy) autologous FCs at a ratio of 20:1 (feeder: NK) in the presence or absence of IL-21 (100 ng/mL). Additionally, expanded NK cells were gene modified to express chimeric antigen receptors (CARs) against CD123, a common marker for acute myeloid leukemia (AML). Cytotoxicity, degranulation, and cytokine release of transduced NK cells were determined against KG1a cells in flow cytometric analysis and fluorescent imaging. The Prodigy manufacturing process revealed high target cell viabilities (median 95.4%), adequate NK cell recovery (median 60.4%), and purity of 95.4% in regard to CD56 + CD3 - target cells. The process in its early phase of development led to a median T-cell depletion of log 3.5 after CD3 depletion and log 3.6 after the whole process, including CD3

  20. (Value Stream Costing As A New Costing System)

    OpenAIRE

    Karcıoğlu, Reşar; Nuray, Meral

    2010-01-01

    In recent years, the number of lean company which use lean manufacturing system is rising. This companies use the standard costing while appropriate for traditional bathch manufacturing. But standard costing system fails to support the goals of lean manufacturing system. A different method of costing based upon the characteristics of the value stream is needed to fulfill the needs of the lean company. This systemis Value Stream Costing. When a lean company moves to value stream management, th...

  1. Controlling nuclear retrofit costs

    International Nuclear Information System (INIS)

    Gruber, C.O.

    1985-01-01

    Increased safety regulations that required modifications to nuclear power plants have had an impact on the capital and expense budgets of utilities. The author addresses the budgeting and control of project-related expenditures, and notes the importance of total cost management throughout the project's life cycle. That total includes the systems, procedures, personnel, expertise, and organization involved in the process. A rational and structured evaluation process at the beginning, realistic targets, and an organizational framework are key components. 2 references, 3 figures, 1 table

  2. Public power costs less

    International Nuclear Information System (INIS)

    Moody, D.

    1993-01-01

    The reasons why residential customers of public power utilities paid less for power than private sector customers is discussed. Residential customers of investor-owned utilities (IOU's) paid average rates that were 28% above those paid by customers by possibly owned systems during 1990. The reasons for this disparity are that management costs faced by public power systems are below those of private power companies, indicating a greater efficiency of management among public power systems, and customer accounts expenses averaged $33.00 per customer for publicly owned electric utilities compared to $39.00 per customer for private utilities

  3. Low cost submarine robot

    Directory of Open Access Journals (Sweden)

    Ponlachart Chotikarn

    2010-10-01

    Full Text Available A submarine robot is a semi-autonomous submarine robot used mainly for marine environmental research. We aim todevelop a low cost, semi-autonomous submarine robot which is able to travel underwater. The robot’s structure was designedand patented using a novel idea of the diving system employing a volume adjustment mechanism to vary the robot’s density.A light weight, flexibility and small structure provided by PVC can be used to construct the torpedo-liked shape robot.Hydraulic seal and O-ring rubbers are used to prevent water leaking. This robot is controlled by a wired communicationsystem.

  4. Activity-Based Costing: A Cost Management Tool.

    Science.gov (United States)

    Turk, Frederick J.

    1993-01-01

    In college and university administration, overhead costs are often charged to programs indiscriminately, whereas the support activities that underlie those costs remain unanalyzed. It is time for institutions to decrease ineffective use of resources. Activity-based management attributes costs more accurately and can improve efficiency. (MSE)

  5. The Distributed Wind Cost Taxonomy

    Energy Technology Data Exchange (ETDEWEB)

    Forsyth, Trudy; Jimenez, Tony; Preus, Robert; Tegen, Suzanne; Baring-Gould, Ian

    2017-03-28

    To date, there has been no standard method or tool to analyze the installed and operational costs for distributed wind turbine systems. This report describes the development of a classification system, or taxonomy, for distributed wind turbine project costs. The taxonomy establishes a framework to help collect, sort, and compare distributed wind cost data that mirrors how the industry categorizes information. The taxonomy organizes costs so they can be aggregated from installers, developers, vendors, and other sources without losing cost details. Developing a peer-reviewed taxonomy is valuable to industry stakeholders because a common understanding the details of distributed wind turbine costs and balance of station costs is a first step to identifying potential high-value cost reduction opportunities. Addressing cost reduction potential can help increase distributed wind's competitiveness and propel the U.S. distributed wind industry forward. The taxonomy can also be used to perform cost comparisons between technologies and track trends for distributed wind industry costs in the future. As an initial application and piloting of the taxonomy, preliminary cost data were collected for projects of different sizes and from different regions across the contiguous United States. Following the methods described in this report, these data are placed into the established cost categories.

  6. Reducing maintenance costs

    International Nuclear Information System (INIS)

    Zaiss, W.; Reuschle, K.; Baier, B.

    2002-01-01

    The increasingly more expensive maintenance measures, cuts in the cost budget, and the loss of know-how on the part of vendors all require a change of policy with respect to maintenance concepts of the part of operators. This also applies to the existing valve concepts, the drives included. Under these aspects, the current drive, which is self-actuated and actuated by outside media, for a parallel-plate valve of a nomial width of 700 was reconsidered. The effort served to reduce maintenance costs and, at the same time, simplify the drive concept as well as cut back on the number of in-service inspections. Moreover, the number of active components were to be minimized and installation conditions in the plant were to be improved. When the boundary conditions to be observed with respect to process technology had been laid down, the competent technical department developed a concept of modification of the drive. A major constituent part was the demonstration of the functioning capability of the new drive under accident conditions. It was achieved mainly by an analytical approach. In the resultant drive concept, the same control valves are employed to actuate a driving cylinder by means of self-actuation or by an outside medium as a function of pressure. (orig.) [de

  7. National Variation in Urethroplasty Cost and Predictors of Extreme Cost: A Cost Analysis With Policy Implications.

    Science.gov (United States)

    Harris, Catherine R; Osterberg, E Charles; Sanford, Thomas; Alwaal, Amjad; Gaither, Thomas W; McAninch, Jack W; McCulloch, Charles E; Breyer, Benjamin N

    2016-08-01

    To determine which factors are associated with higher costs of urethroplasty procedure and whether these factors have been increasing over time. Identification of determinants of extreme costs may help reduce cost while maintaining quality. We conducted a retrospective analysis using the 2001-2010 Healthcare Cost and Utilization Project-Nationwide Inpatient Sample (HCUP-NIS). The HCUP-NIS captures hospital charges which we converted to cost using the HCUP cost-to-charge ratio. Log cost linear regression with sensitivity analysis was used to determine variables associated with increased costs. Extreme cost was defined as the top 20th percentile of expenditure, analyzed with logistic regression, and expressed as odds ratios (OR). A total of 2298 urethroplasties were recorded in NIS over the study period. The median (interquartile range) calculated cost was $7321 ($5677-$10,000). Patients with multiple comorbid conditions were associated with extreme costs [OR 1.56, 95% confidence interval (CI) 1.19-2.04, P = .02] compared with patients with no comorbid disease. Inpatient complications raised the odds of extreme costs (OR 3.2, CI 2.14-4.75, P costs (OR 1.78, 95% CI 1.2-2.64, P = .005). Variations in patient age, race, hospital region, bed size, teaching status, payor type, and volume of urethroplasty cases were not associated with extremes of cost. Cost variation for perioperative inpatient urethroplasty procedures is dependent on preoperative patient comorbidities, postoperative complications, and surgical complexity related to graft usage. Procedural cost and cost variation are critical for understanding which aspects of care have the greatest impact on cost. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. The many costs of sex.

    Science.gov (United States)

    Lehtonen, Jussi; Jennions, Michael D; Kokko, Hanna

    2012-03-01

    Explaining the evolution of sex is challenging for biologists. A 'twofold cost' compared with asexual reproduction is often quoted. If a cost of this magnitude exists, the benefits of sex must be large for it to have evolved and be maintained. Focusing on benefits can be misleading, as this sidelines important questions about the cost of sex: what is the source of the twofold cost: males, genome dilution or both? Does the cost deviate from twofold? What other factors make sex costly? How should the costs of sex be empirically measured? The total cost of sex and how it varies in different contexts must be known to determine the benefits needed to account for the origin and maintenance of sex. Copyright © 2011 Elsevier Ltd. All rights reserved.

  9. An Analytical Cost Estimation Procedure

    National Research Council Canada - National Science Library

    Jayachandran, Toke

    1999-01-01

    Analytical procedures that can be used to do a sensitivity analysis of a cost estimate, and to perform tradeoffs to identify input values that can reduce the total cost of a project, are described in the report...

  10. Cost effectiveness analysis in radiopharmacy

    International Nuclear Information System (INIS)

    Carpentier, N.; Verbeke, S.; Ducloux, T.

    1999-01-01

    Objective: to evaluate the cost effectiveness of radiopharmaceuticals and their quality control. Materials and methods: this retrospective study was made in the Nuclear Medicine Department of the University Hospital of Limoges. Radiopharmaceutical costs were obtained with adding the price of the radiotracer, the materials, the equipments, the labour, the running expenses and the radioisotope. The costs of quality control were obtained with adding the price of labour, materials, equipments, running expenses and the cost of the quality control of 99m Tc eluate. Results: during 1998, 2106 radiopharmaceuticals were prepared in the Nuclear Medicine Department. The mean cost effectiveness of radiopharmaceutical was 1430 francs (846 to 4260). The mean cost effectiveness of quality control was 163 francs (84 to 343). The rise of the radiopharmaceutical cost induced by quality control was 11%. Conclusion: the technical methodology of quality control must be mastered to optimize the cost of this operation. (author)

  11. Modeling of GE Appliances: Cost Benefit Study of Smart Appliances in Wholesale Energy, Frequency Regulation, and Spinning Reserve Markets

    Energy Technology Data Exchange (ETDEWEB)

    Fuller, Jason C.; Parker, Graham B.

    2012-12-31

    This report is the second in a series of three reports describing the potential of GE’s DR-enabled appliances to provide benefits to the utility grid. The first report described the modeling methodology used to represent the GE appliances in the GridLAB-D simulation environment and the estimated potential for peak demand reduction at various deployment levels. The third report will explore the technical capability of aggregated group actions to positively impact grid stability, including frequency and voltage regulation and spinning reserves, and the impacts on distribution feeder voltage regulation, including mitigation of fluctuations caused by high penetration of photovoltaic distributed generation. In this report, a series of analytical methods were presented to estimate the potential cost benefit of smart appliances while utilizing demand response. Previous work estimated the potential technical benefit (i.e., peak reduction) of smart appliances, while this report focuses on the monetary value of that participation. The effects on wholesale energy cost and possible additional revenue available by participating in frequency regulation and spinning reserve markets were explored.

  12. Cost Model for Digital Curation: Cost of Digital Migration

    DEFF Research Database (Denmark)

    Kejser, Ulla Bøgvad; Nielsen, Anders Bo; Thirifays, Alex

    2009-01-01

    The Danish Ministry of Culture is currently funding a project to set up a model for costing preservation of digital materials held by national cultural heritage institutions. The overall objective of the project is to provide a basis for comparing and estimating future financial requirements...... for digital preservation and to increase cost effectiveness of digital preservation activities. In this study we describe an activity based costing methodology for digital preservation based on the OAIS Reference Model. In order to estimate the cost of digital migrations we have identified cost critical...

  13. Wind Integration Cost and Cost-Causation: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Milligan, M.; Kirby, B.; Holttinen, H.; Kiviluoma, J.; Estanqueiro, A.; Martin-Martinez, S.; Gomez-Lazaro, E.; Peneda, I.; Smith, C.

    2013-10-01

    The question of wind integration cost has received much attention in the past several years. The methodological challenges to calculating integration costs are discussed in this paper. There are other sources of integration cost unrelated to wind energy. A performance-based approach would be technology neutral, and would provide price signals for all technology types. However, it is difficult to correctly formulate such an approach. Determining what is and is not an integration cost is challenging. Another problem is the allocation of system costs to one source. Because of significant nonlinearities, this can prove to be impossible to determine in an accurate and objective way.

  14. Cost analysis of reliability investigations

    International Nuclear Information System (INIS)

    Schmidt, F.

    1981-01-01

    Taking Epsteins testing theory as a basis, premisses are formulated for the selection of cost-optimized reliability inspection plans. Using an example, the expected testing costs and inspection time periods of various inspection plan types, standardized on the basis of the exponential distribution, are compared. It can be shown that sequential reliability tests usually involve lower costs than failure or time-fixed tests. The most 'costly' test is to be expected with the inspection plan type NOt. (orig.) [de

  15. Nuclear power generation cost methodology

    International Nuclear Information System (INIS)

    Delene, J.G.; Bowers, H.I.

    1980-08-01

    A simplified calculational procedure for the estimation of nuclear power generation cost is outlined. The report contains a discussion of the various components of power generation cost and basic equations for calculating that cost. An example calculation is given. The basis of the fixed-charge rate, the derivation of the levelized fuel cycle cost equation, and the heavy water charge rate are included as appendixes

  16. Batteries: Lower cost than gasoline?

    International Nuclear Information System (INIS)

    Werber, Mathew; Fischer, Michael; Schwartz, Peter V.

    2009-01-01

    We compare the lifecycle costs of an electric car to a similar gasoline-powered vehicle under different scenarios of required driving range and cost of gasoline. An electric car is cost competitive for a significant portion of the scenarios: for cars of lower range and for higher gasoline prices. Electric cars with ∼150 km range are a technologically viable, cost competitive, high performance, high efficiency alternative that can presently suit the vast majority of consumers' needs.

  17. Quality cost system in electronics

    International Nuclear Information System (INIS)

    Denzer, H.O.

    1978-01-01

    A description is presented of a formal cost of quality system used in an electronic manufacturing facility. The system elements and reports are illustrated. Examples of the use of a quality cost system to measure quality performance and to improve product quality are included. A comparison to industry averages for quality costs is made. The paper attempts to show that the collection and use of quality costs are an aid to management and can be accompanied by improved product quality

  18. Space Station Freedom operations costs

    Science.gov (United States)

    Accola, Anne L.; Williams, Gregory J.

    1988-01-01

    Measures to reduce the operation costs of the Space Station which can be implemented in the design and development stages are discussed. Operational functions are described in the context of an overall operations concept. The provisions for operations cost responsibilities among the partners in the Space Station program are presented. Cost estimating methodologies and the way in which operations costs affect the design and development process are examined.

  19. Collider Scaling and Cost Estimation

    International Nuclear Information System (INIS)

    Palmer, R.B.

    1986-01-01

    This paper deals with collider cost and scaling. The main points of the discussion are the following ones: 1) scaling laws and cost estimation: accelerating gradient requirements, total stored RF energy considerations, peak power consideration, average power consumption; 2) cost optimization; 3) Bremsstrahlung considerations; 4) Focusing optics: conventional, laser focusing or super disruption. 13 refs

  20. Server farms with setup costs

    NARCIS (Netherlands)

    Gandhi, A.; Harchol-Balter, M.; Adan, I.J.B.F.

    2010-01-01

    In this paper we consider server farms with a setup cost. This model is common in manufacturing systems and data centers, where there is a cost to turn servers on. Setup costs always take the form of a time delay, and sometimes there is additionally a power penalty, as in the case of data centers.